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Sample records for intestinal masiva proceso

  1. Resección intestinal masiva: Proceso de adaptación nutricional Massive intestinal resection: Nutritional adaptation process

    OpenAIRE

    S. Leyva-Martínez; S. Fernández-Lloret; J. L. Martín-Ruiz

    2007-01-01

    Introducción: La resección masiva de intestino delgado (RMID) con remanente inferior a los 60 cm de yeyuno ocasiona una grave depleción hidroelectrolítico-vitamínica y calórico-proteica. En espera de trasplante intestinal viable la mayoría de RMID dependen de la Nutrición Parenteral (NPT). Caso clínico: Varón de 32 años. RMID por traumatismo seccionante de la raíz de la arteria mesentérica superior. En primera intervención de urgencia : yeyunostomía con resección de I. Delgado, colon derecho ...

  2. MODIFICACIÓN AL PROCESO DE PRODUCCIÓN MASIVA DE LOS PARASITOIDES Catolaccus grandis Y Catolaccus hunteri

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    Marco Antonio Reyes-Rosas

    2010-01-01

    Full Text Available El presente estudio se realizó con el objetivo de modificar la tecnología de producción masiva de Catolaccus grandis y Catolaccus hunteri, himenópteros parasitoides de Anthonomus grandis el picudo del algodonero en Tamaulipas, México en el 2002. Se determinó la eficiencia del papel toalla para el secado de manos, en el sellamiento de cápsulas moldeadas en cera de hidrocarburos y poliolefina (LCHP, donde se confina al huésped, y evaluar la efectividad del gorgojo del garbanzo Callosobruchus maculatus como hospedante facticio para la cría de ambos parasitoides. Hubo producción masiva de C. grandis y C. hunteri utilizando C. maculatus como huésped y el papel toalla fue efectivo para sellar los orificios de las cápsulas moldeadas en LCHP. La producción masiva de C. grandis y C. hunteri mediante C. maculatus, contribuyó a incrementar la seguridad y facilidad del proceso, además de una significativa reducción de costos. El papel toalla en el sellado de los orificios de las cápsulas moldeadas en LCHP, redujo en un 50% por m2 los costos del proceso, sin afectar la eficiencia del parasitismo y emergencia de C. grandis.

  3. Las negociaciones en el proceso penal: del procedimiento inquisitivo a la prisionización masiva

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    Julio César Montañez Ruiz

    2013-12-01

    Full Text Available La presente investigación plantea la problemática de la prisionización masiva que generan las negociaciones en el sistema procesal penal de tendencia acusatoria, con marcada influencia norteamericana; aquí se sostiene que ese mecanismo, mediante el cual la Fiscalía busca la declaratoria masiva de culpabilidad de los imputados en plan de descongestionar el sistema represivo penal, tiene las caraterísticas más inquisitivas de un sistema de enjuiciamiento penal.

  4. Arsenoterapia masiva

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    Efraím Cabrera

    1940-02-01

    Full Text Available En abril de 1939, el doctor Bernardo de Castro me entregaba un número de "The American Journal of the Medical Science", en donde el maestro americano Harold Thomas Hyman del Hospital Monte Sinaí de Nueva York, publicaba un estudio de 25 casos de Sifilis reciente, tratados por medio de la arsenoterapia masiva. Busca el insigne investigador americano el ideal terapéutico del sabio Erlich: La Sterilisatio Magna: Saturar al paciente de la droga terapéutica antiluética (en este caso el arsénico, y mantener la curva de saturación mas o menos constante durante un cierto tiempo, consiguiendo, de esta suerte la muerte de todos los espiroquetos que alberga el organismo del paciente, por lo tanto su esterilización, frente a la Sífilis.

  5. SISTEMA PARA LA ADMINISTRACIÓN DE MATERIALES EN PROYECTOS DE CONSTRUCCIÓN MASIVA DE VIVIENDA

    OpenAIRE

    José Antonio González Fajardo; Carlos Enrique Arcudia Abad; Sergio Omar Álvarez Romero

    2002-01-01

    Se propone un sistema para administrar los recursos materiales que intervienen en la construcción masiva de unidades habitacionales o vivienda unifamiliar. Esta propuesta es en sí, un planteamiento global de todas las etapas, fases y procesos administrativos que se consideran importantes integrar para llevar a cabo con éxito la función referida; se considera la administración de los materiales
    desde el desarrollo del diseño del proyecto hasta su utilización dentro de los procesos c...

  6. Hemorragia digestiva baja masiva en pacientes con enfermedad de Crohn

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    M. Barreiro de Acosta

    Full Text Available Objetivo: analizar la frecuencia de las hemorragias masivas en la EC e intentar determinar sus potenciales factores de riesgo (ambientales, propios de la enfermedad y genéticos. Material y métodos: se estudió de manera retrospectiva una cohorte de 174 pacientes -103 mujeres (59% y 71 hombres (41%, edad media de 37 años- con EC, analizándose las hemorragias digestivas masivas que se habían producido en relación con su enfermedad. Se revisaron asimismo potenciales factores de riesgo como hábito tabáquico, localización de la enfermedad y presencia de mutaciones genéticas en CARD15, RTL-4 y CD14, entre otros. Resultados: tres pacientes (1,7% presentaron una hemorragia digestiva masiva que precisó intervención quirúrgica para su resolución. Esta indicación de cirugía supone el 3,4% de las cirugías en relación con la EC. Todos los pacientes eran jóvenes y su enfermedad seguía un patrón inflamatorio y estaba localizada en el íleon. No se ha evidenciado asociación estadísticamente significativa entre las hemorragias digestivas masivas y los potenciales factores de riesgo analizados. Conclusiones: la hemorragia digestiva baja masiva es una complicación poco común, aunque grave de la EC. Se trata habitualmente de pacientes con patrón inflamatorio de la enfermedad y afectación ileal. Para su diagnóstico resulta clave la asociación de endoscopia y arteriografía, y su resolución suele ser quirúrgica.

  7. SISTEMA PARA LA ADMINISTRACIÓN DE MATERIALES EN PROYECTOS DE CONSTRUCCIÓN MASIVA DE VIVIENDA

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    José Antonio González Fajardo

    2002-07-01

    Full Text Available Se propone un sistema para administrar los recursos materiales que intervienen en la construcción masiva de unidades habitacionales o vivienda unifamiliar. Esta propuesta es en sí, un planteamiento global de todas las etapas, fases y procesos administrativos que se consideran importantes integrar para llevar a cabo con éxito la función referida; se considera la administración de los materiales
    desde el desarrollo del diseño del proyecto hasta su utilización dentro de los procesos constructivos, pasando a través de las etapas de planeación, programación y control de los mismos.Se estima haber alcanzado un alto nivel de detalle en cada una de las etapas que se definieron. Se aprovechan las características particulares de administración que se presentan en los proyectos de construcción masiva de vivienda, debido al carácter repetitivo de las unidades habitacionales.Para el desarrollo del sistema se tomaron en cuenta aspectos tales como la administración efectiva de proyectos y su impacto en la productividad de las empresas constructoras de este ramo, así como la situación actual, necesidades y opiniones de los ejecutivos de estas empresas.

  8. Ascitis fetal masiva idiopática aislada

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    Yolimar Navarro Briceño

    2016-08-01

    Full Text Available La ascitis fetal esta comúnmente asociada a malformaciones gastrointestinales y urinarias, anemia, infección y anomalías cromosómicas. La ascitis fetal masiva idiopática es rara. Se reporta un caso de una embarazada de 33 años referida a las 17 semanas después que se detectó ascitis en ausencia de anomalías estructurales. La evaluación cardiaca y las pruebas diagnósticas de infecciones virales fueron negativas. A las 28 semanas se detectó ascitis masiva sin otros signos de hidrops fetal. La velocidad sistólica pico de la arteria cerebral media fetal estaba elevada. El Doppler de la arteria umbilical, crecimiento fetal y volumen de líquido amniótico estaban normales. El ecocardiograma fetal estaba normal. Se realizó la amniocentesis con resultados normales del cariotipo. A pesar de la persistencia de la ascitis masiva durante el seguimiento, el crecimiento fetal y el volumen de líquido amniótico eran normales con valores elevados de la velocidad sistólica pico de la arteria cerebral media fetal. A las 33 semanas la paciente se realizó cesárea de emergencia por sufrimiento fetal agudo. Se obtuvo un recién nacido vivo femenino normal con valores normales de hemoglobina al nacer. El flujo vascular hepático, vesical y hepato-portal fueron normales. La ascitis se resolvió completamente al octavo día después del nacimiento y el recién nacido fue dado de alta a los 15 días.

  9. LA COMUNICACIÓN MASIVA Y EL COMPORTAMIENTO DEL CONSUMIDOR

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    Natalia Golovina

    2014-07-01

    Full Text Available En el presente escrito utilizando las técnicas de investigación documental se hace un análisis de la comunicación masiva en dos direcciones: como herramienta de poder de las empresas sobre los consumidores, causando los efectos cognitivos, afectivos y actitudinales, moldeando los motivos de compra y como el medio de ejercicio de poder de los consumidores sobre las empresas, obligándolas actuar con mayor ética y transparencia, a través de la posibilidad de hacer públicas sus opiniones y valoraciones tanto positivas como negativas sobre un determinado producto, imagen corporativa, posicionamiento de la marca, calidad de los mensajes publicitarios.

  10. Embolectomía en una embolia pulmonar aguda masiva

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    Manuel Carnero Alcázar

    2007-07-01

    Full Text Available Presentamos el caso de un varón de 57 años que, en el seno de un meningioma microcítico, padece una tromboembolia pulmonar masiva aguda con inestabilidad hemodinámica. Dado el riesgo de hemorragia por el tumor craneal, se contraindica la terapia fibrinolítica y se procede a practicar embolectomía pulmonar. Ésta se realiza bajo anestesia general, con canulación convencional y bajo hipotermia moderada. Se extrae émbolo en el tronco de la arteria pulmonar y con catéter de Fogarty se extraen émbolos en ramas lobares y segmentarias. Discutimos la asociación de enfermedad tromboembólica con determinadas neoplasias y el tratamiento de la tromboembolia pulmonar

  11. Impacto de los medios de comunicación masiva en una campaña antitabaco

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    Sansores Raúl H

    2002-01-01

    Full Text Available Objetivo. Determinar en México el impacto de los medios de comunicación masiva (MCM en el proceso de dejar de fumar. Material y métodos. Evaluamos, entre junio de 1998 y mayo de 1999, el efecto de una campaña en los MCM de México, así como el de estrategias alternas, comparando el promedio mensual de ventas de todos los productos auxiliares para dejar de fumar antes y después del lanzamiento de un Parche Nuevo de nicotina. Se usó t pareada o de Student para comparar las ventas. Resultados. Las ventas totales aumentaron de 24 206±4 558 a 55 604±8 993 (p<0.0001. Estimamos que 1 853 fumadores intentaron dejar de fumar y 96 lo consiguieron diariamente con un solo producto después de la promoción. Estrategias alternas para conseguir resultados similares indican que programas de una institución del sector público podrían conseguir que seis personas dejaran de fumar y 501 lo intentaran diariamente. Conclusiones. Los MCM tienen un efecto poderoso en el proceso para dejar de fumar y la inclusión de más instituciones del sector público podría igualar lo obtenido por el sector privado.

  12. SECCIÓN TEMÁTICA - 5. LA EVACUACIÓN MASIVA // MASS EVACUATION

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    Alexis Lorenzo Ruiz

    2012-06-01

    Full Text Available Ante la inminente amenaza de un huracán, volcán, incendio o incluso ante un riesgo nuclear, el factor que más vidas salva es la evacuación oportuna. Esta medida no solo depende de la capacidad organizativa en el momento de la catástrofe, sino también de una adecuada reacción social. La respuesta social a una evacuación masiva está determinada principalmente por el nivel de confianza entre autoridades y sociedad civil. Alcanzar dichos niveles requiere de un ejercicio de gobierno que invierta tanto en factores tangibles (tales como políticas públicas, sistemas de aviso temprano y otros recursos, como en atributos intangibles (v.g., formación de Capital Social y capacitación ciudadana.Bajo esta premisa, la seguridad y rapidez con que se desarrollan las evacuaciones por la proximidad de un huracán en un país con escasos recursos económicos como Cuba, merece de un estudio que indague en los factores no tangibles que coadyuvan al éxito de este proceso. A partir de un extenso trabajo documental y mediante la aplicación de entrevistas individuales y grupales, este texto examina las movilizaciones ciudadanas cubanas producidas por el posible impacto de un evento hidrometeorológico extremo y el valor de la inversión en capital social y cognitivo en la construcción de relaciones de confianza en situaciones de riesgo.

  13. Manual práctico de reproducción masiva de Amblyseius californicus, usado en el control biológico de Tetranychus urticae

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    Colcha Rovalino, Segundo Efraín

    2013-01-01

    El Manual práctico de reproducción masiva de (Amblyseius californicus), usado en el control biológico de (Tetranychus urticae), brindará una alternativa válida y efectiva para el control del ácaros plaga, explicando paso a paso todos los procesos que conllevan a obtener la reproducción del ácaro benéfico hasta su liberación y control en el campo, y así garantizar el éxito, sin pérdidas de cosecha por la implementación de este método biológico, reemplazando al método químico que a la ves caus...

  14. El proceso

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    Vargas-Pons, Carlos

    2000-01-01

    Texto del artista plástico Carlos Vargas Pons sobre su propio proceso creativo. Se incluyen reproducciones a color de las siguientes obras: "La siesta", "Zacarías sobre la mesa de una mujer sin amor (según Buñuel)", "Posterior al baño (según Ingres)" y "Orador (según Jean de Cambrai)".

  15. Reprogramación celular de embriones de Anthurium andraeanum por fitohormonas para micropropagación masiva

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    Julieta Mireles-Ordaz

    2015-01-01

    Full Text Available El género Anthurium incluye alrededor de 800 especies, las cuales son originarias de diversos países tropicales y subtropicales de América. Numerosos cultivos de estas especies de Anthurium son crecidos y comercializados debido a su gran popularidad como plantas ornamentales alrededor de todo el mundo, de las cuales la más popular es Anthurium andreanum. La reproducción sexual de estas plantas en invernaderos es difícil y toma mucho tiempo, lo cual representa una desventaja para su producción masiva y comercialización. La micropropagación in vitro ha emergido como una opción para sobrellevar dicha desventaja, hasta la fecha se han logrado avances parcialmente exitosos en la micropropagación en especies de Anthurium usando varios tejidos como explantes iniciales, incluyendo hojas, pecíolo, espádice, espata, brote lateral, meristemo apical y embriones somáticos, estos últimos previamente inducidos a partir de tejido diferenciado. Sin embargo, hasta ahora no hay reportes del uso de embriones cigóticos como tejido madre para la propagación masiva de estas plantas. En el presente estudio reportamos la formación de callos organogénicos a partir de embriones cigóticos inmaduros crecidos en medio MS suplementado con la combinación de 2 mg/l de ácido 2,4-diclorofenoxiacético (2,4-D y 0.5 mg/l de 6-benzilamino-purina (BAP. Los resultados obtenidos demuestran que los embriones en proceso de desarrollo son altamente eficientes como explantes de origen para inducir la formación de tejido calloso de una manera rápida y fácil, dando en promedio 9 brotes por callo y logrando una taza de sobrevivencia de las plantas del 90% en la fase de aclimatación.

  16. Complicaciones asociadas a la transfusión de hemocomponentes en hemorragias masivas.

    OpenAIRE

    Polo Morís, Bibiana

    2016-01-01

    Evaluar si las complicaciones postransfusionales en las hemorragias masivas son mayores en pacientes a los que no se le han realizado pruebas cruzadas pretransfusionales en comparación con pacientes a los que sí se le han realizado.Analizar que complicaciones postransfusionales se dan con mayor frecuencia.

  17. Culturas fan y cultura masiva: prácticas e identidades juveniles de otakus y gamers

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    Federico Álvarez Gandolfi

    2015-01-01

    Full Text Available [es] El objetivo de este trabajo es dar cuenta de cómo, en torno de productos mediáticos y prácticas socioculturales comunes, los fans del anime o series animadas japonesas –autodenominados otakus– y los fans de los videojuegos japoneses –autodenominados gamers– elaboran un universo simbólico propio y compartido sobre el cual pueden construir identidades juveniles que son diferentes entre sí. El interés por las significaciones que producen estos fans surge del auge de la cultura masiva japonesa en la Argentina, evidenciado, por ejemplo, en la transmisión de distintos animes por las emisoras nacionales de televisión por aire Telefe y Canal 9, en ciclos organizados por la Facultad de Ciencias Sociales de la Universidad de Buenos Aires y en documentales del Canal Encuentro –gestionado por el Ministerio de Educación de la Nación Argentina–, así como en la promoción institucional de dichas series animadas y de los videojuegos en Tecnópolis –muestra nacional de arte, ciencia y tecnología–, la Feria Internacional del Libro de Buenos Aires y la Agenda Cultural del Gobierno de la Ciudad de Buenos Aires. Es así como, desde una perspectiva socioantropológica y comunicacional, cabe reflexionar sobre los usos y reapropiaciones que hacen los jóvenes fans de los objetos de la cultura de masas japonesa que viven en la Ciudad de Buenos Aires. Asimismo, hay que tener en cuenta que las distintas prácticas desarrolladas en torno del consumo de estos productos están encuadradas dentro de flujos globales que generan procesos interculturales de construcción de identidades, inscriptos a la vez en relaciones de poder intraculturales y procesos alternativos de producción cultural. [en] This work aims to give an account of how fans of anime or Japanese animated series –self-described otakus– and fans of Japanese video games –self-described gamers– create their own and shared symbolic universe around common media products and

  18. Las mediciones masivas: una producción política de sentidos y significados sobre los sistemas educativos

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    Carmenza Sánchez Rodríguez

    2017-03-01

    Full Text Available El artículo recoge reflexiones producto de revisiones documentales y discusiones con docentes y expertos en evaluación educativa. Lo cual ha permito trascender la comprensión de la evaluación desde una práctica técnica a una práctica política producida desde una visión de mundo que legitima e instala ciertos sentidos y significados sobre los sistemas educativos y sus actores, generando unas formas específicas de relación y organización que producen exclusión. En esta perspectiva se analizan algunos de los sentidos y significados producidos por las prácticas de medición masivas que, presentadas como una práctica técnica, obvian la discusión de las visiones de mundo, concepciones y valoraciones desde las cuales son producidas. Se abordan las concepciones sobre la evaluación, el conocimiento evaluado, las culturas reconocidas y los procesos de exclusión que se generan a partir de estas prácticas, así como sus efectos para las instituciones y los sujetos, concluyendo que las pruebas son invenciones del siglo XX, y los problemas pedagógicos y técnicos que ocultan no han sido discutidos, pero especialmente se han ignorado sus implicaciones en términos de calidad y equidad y su papel político en la reproducción y legitimación de las diferencias.

  19. Impacto de los medios de comunicación masiva en una campaña antitabaco

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    Raúl H Sansores

    2002-01-01

    Full Text Available Objetivo. Determinar en México el impacto de los medios de comunicación masiva (MCM en el proceso de dejar de fumar. Material y métodos. Evaluamos, entre junio de 1998 y mayo de 1999, el efecto de una campaña en los MCM de México, así como el de estrategias alternas, comparando el promedio mensual de ventas de todos los productos auxiliares para dejar de fumar antes y después del lanzamiento de un Parche Nuevo de nicotina. Se usó t pareada o de Student para comparar las ventas. Resultados. Las ventas totales aumentaron de 24 206±4 558 a 55 604±8 993 (pAbstract Objective To assess the impact of the mass media (MM on smoking cessation process in Mexico. Material and Methods. Between June 1998 and May 1999, the effects of an anti-smoking mass media campaign and alternative strategies were evaluated, by comparing the monthly sales average of all smoking-cessation aid products before and after marketing a new nicotine patch. Student's t paired and unpaired t tests were used to compare sales. Results. Total sales increased from 24 206±4 558 to 55 604±8 993 (p<0.0001. It was estimated that 1 853 smokers tried to quit and 96 per day succeeded with a single product after the campaign. Alternative strategies to get similar results indicate that the programs of a single public sector institution could help 501 persons attempt quitting smoking and six to accomplish it per day. Conclusions. The mass media have a powerful effect on smoking cessation practices; the involvement of more public institutions may accomplish similar results as the private sector.

  20. El legado del Movimiento Moderno. Conjuntos de vivienda masiva en ciudades europeas del Oeste y del Este. No tan diferentes…

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    Javier Monclús

    2015-05-01

    Full Text Available El objetivo de este artículo es comparar y contrastar algunos conjuntos de vivienda modernos en ciudades europeas del Oeste (“capitalistas” y del Este (“socialistas”. Nuestro trabajo se centra en conjuntos de vivienda masiva construidos en el periodo de crecimiento urbano acelerado que tuvo lugar en Europa principalmente en las décadas de los años 60 y 70 del pasado siglo. El punto de partida más obvio es que las ciudades socialistas son diferentes de las europeas occidentales por la distinta naturaleza de sus políticas urbanas, el sistema de planificación económica socialista centralizada, la ausencia de un mercado del suelo libre, el impacto de la industrial­ización en el sector de la construcción, etc. Sin embargo, hay muchos conceptos en urbanismo, así como en los procesos urbanos, que fueron compartidos en ambos sistemas políticos e ideológicos. El artículo ofrece una perspectiva comparada de la naturaleza de esos conjuntos residenciales modernos construidos a ambos lados del Telón de Acero –Housing Es­tates en UK, Grands Ensembles en Francia, Großsiedlungen en Alemania, Polígonos en España o los grandes conjuntos residenciales socialistas en los países del Bloque del Este– con el fin de entender mejor si –y hasta qué punto– las formas urbanas de dichos conjuntos son el resultado de la cultura internacional del urbanismo moderno.

  1. Cultura migratoria y comunicación masiva e interpersonal en los imaginarios juveniles

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    Martín Echeverría Victoria

    2013-01-01

    A partir de una propuesta acerca de la participación central de la comunicación interpersonal y masiva en la cultura de la migración, mediante los imaginarios que aquella produce, presentamos datos empíricos de jóvenes migrantes potenciales de una comunidad de Yucatán que demuestran que las noticias y las narrativas socializadas y apropiadas colectivamente, en efecto contribuyen a persuadir o disuadir a los sujetos a emigrar.

  2. Guía clínica para el manejo interdisciplinario del paciente con secuelas de pérdida masiva de peso durante la cirugía plástica reconstructiva

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    Alejandro Portes-Castro

    2016-03-01

    Full Text Available Antecedentes y Objetivos. La obesidad está considerada como una pandemia y México ocupa uno de los primeros lugares mundiales en número de casos en población adulta y el primero en el grupo infantil. Desde 2008 se pusieron en marcha Unidades de Cirugía Bariátrica para el manejo del paciente obeso, con lo cual se inició también la Reconstrucción postpérdida masiva de peso por los Servicios de Cirugía Plástica. Sin embargo, no existen protocolos descritos de manejo perioperatorio de este tipo de pacientes en nuestro país. El objetivo del presente trabajo es crear una guía clínica para el manejo interdisciplinario del paciente con secuelas de pérdida masiva de peso basada en los resultados obtenidos en un centro de reconstrucción postbariátrica. Material y Método. Creamos para ello un equipo de expertos de cada área involucrada y se estandarizó el manejo pre, trans y postoperatorio de todos los pacientes con secuelas de pérdida masiva de peso a fin de evaluar los resultados obtenidos. Resultados. Se realizaron 314 procedimientos reconstructivos en 144 pacientes postbariátricos. El 93% fueron de sexo femenino. La edad promedio fue de 37.2 años. Los procedimientos realizados fueron: abdominoplastia en un 39.17%; mastopexia en un 10.5%; torsoplastia en un 7.69%; braquioplastia en un 7.01%; cruroplastia en un 5.09%; y ritidoplastia en un 2.54%. El tiempo quirúrgico promedio fue de 221.2 minutos, con un sangrado transoperatorio medio de 275 ml. Las complicaciones presentadas alcanzaron el 4.77% y la mortalidad fue de 0%. Las recomendaciones emitidas por cada experto involucrado en el proceso de reconstrucción permitieron obtener resultados favorables en relación a la morbi-mortalidad, que fue equiparable e incluso inferior a la reportada en otras series. Conclusiones. Creemos que el seguimiento de una guía clínica basada en la estandarización del manejo de 314 procedimientos en una población con características similares

  3. VASO FERMENTADOR DE BAJO COSTO PARA LA MICROPROPAGACIÓN MASIVA DE JENGIBRE

    OpenAIRE

    Alejandro Hern\\u00E1ndez-Soto; Andr\\u00E9s Gatica-Arias; Silvana Alvarenga-Venutolo

    2008-01-01

    La presente investigación se realizó en el Centro de Investigación en Biotecnología del Instituto Tecnológico de Costa Rica, durante el primer semestre del 2003 y tuvo como objetivo desarrollar un vaso fermentador de bajo costo para la micropropagación masiva de jengibre. El vaso fermentador propuesto en este trabajo tuvo un costo aproximado de $4 USD, con capacidad de utilizar de 50 a 75 brotes como material de partida en 350 ml de medio de cultivo líquido. Cada brote inicial generó alrededo...

  4. Armas pequeñas y ligeras: verdaderas piezas de destrucción masiva

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    Universidad del Rosario

    2013-01-01

    La tenencia, el porte y uso de las armas pequeñas y ligeras (APAL) afecta el desarrollo, la seguridad y la salud en Colombia y en el mundo. Alrededor del planeta hay 875 millones de APAL que causan un muerto cada minuto. Convirtiéndolas en las verdaderas piezas de destrucción masiva elevando día a día los índices de violencia. Un problema que debe entrar en observación por parte de los diferentes gobiernos y el consenso internacional impulsando el desarme como política mundial contra las arma...

  5. VASO FERMENTADOR DE BAJO COSTO PARA LA MICROPROPAGACIÓN MASIVA DE JENGIBRE

    Directory of Open Access Journals (Sweden)

    Alejandro Hern\\u00E1ndez-Soto

    2008-01-01

    Full Text Available La presente investigación se realizó en el Centro de Investigación en Biotecnología del Instituto Tecnológico de Costa Rica, durante el primer semestre del 2003 y tuvo como objetivo desarrollar un vaso fermentador de bajo costo para la micropropagación masiva de jengibre. El vaso fermentador propuesto en este trabajo tuvo un costo aproximado de $4 USD, con capacidad de utilizar de 50 a 75 brotes como material de partida en 350 ml de medio de cultivo líquido. Cada brote inicial generó alrededor de 2,9±1,4 brotes, con una altura de 3,1±0,1cm, un peso fresco de 1,2±0,5 g y un peso seco de 0,24±0,27 por brote.

  6. LAS FAMILIAS MEXICANAS CON ESTATUS INMIGRATORIO MIXTO Y LA DEPORTACIÓN MASIVA DE ESTADOS UNIDOS

    Directory of Open Access Journals (Sweden)

    Guillermo Yrizar Barbosa

    Full Text Available Resumen Ante la creciente criminalización de la inmigración en Estados Unidos, millones de personas que forman parte de familias inmigrantes mexicanas enfrentan miedo, angustia y precariedad social. En este artículo se analiza el impacto que ha tenido la deportación masiva de mexicanos en familias con estatus inmigratorio mixto. En primer lugar, se describe la evolución de la legislación estadounidense que ha facilitado la deportación formal de extranjeros no naturalizados. Posteriormente se examinan algunas de las características sociodemográficas del flujo de personas repatriadas a México. Finalmente se presentan tres casos de padres deportados que pertenecen a familias mexicanas con estatus migratorio mixto que difícilmente pueden ser considerados como criminales.

  7. Regiones de formación de estrellas masivas en las Nubes de Magallanes

    Science.gov (United States)

    Barbá, R.; Maíz Apellániz, J.; Rubio, M.; Walborn, N.

    Las Nubes de Magallanes son un laboratorio formidable para el estudio de regiones de formación estelar. A diferencia de lo que sucede en el plano galáctico, ambas galaxias contienen poco polvo que nos afecte la visión directa de dichas regiones. Por otra parte, la menor metalicidad de las Nubes, nos permiten hacer un estudio comparativo de la formación estelar en ambientes de baja metalicidad. El presente trabajo da una revisión de los progresos notables que hemos alcanzado en el conocimiento del contenido estelar de algunas regiones de formación de estrellas masivas en ambas Nubes, en base a la utilización de imágenes del Telescopio Espacial Hubble, Gemini Sur, y Very Large Telescope, entre otros. En especial, nos concentramos en 30 Doradus y N11 en la Nube Mayor, y en NGC 346 en la Nube Menor. Nuevas imágenes de N11 obtenidas en los últimos meses con la Advanced Camera for Surveys del Hubble (óptico), y con Flamingos en Gemini Sur (infrarrojo), nos han permitido descubrir un nuevo `jet' con origen en una fuente infrarroja sumergida en un pilar polvoriento similar al objeto Herbig-Haro de M20 en nuestra galaxia. Este `jet' (junto a otros tres que hemos descubierto en 30 Doradus), es el cuarto ejemplo confirmado de `jet' asociado a una protoestrella fuera de nuestra galaxia. Además, presentamos el descubrimiento del primer objeto estelar joven masivo de la Nube Menor confirmado espectroscópicamente.

  8. Intestinal Cancer

    Science.gov (United States)

    ... connects your stomach to your large intestine. Intestinal cancer is rare, but eating a high-fat diet ... increase your risk. Possible signs of small intestine cancer include Abdominal pain Weight loss for no reason ...

  9. Nuevo enfoque para el estudio de la productividad en la construcción masiva de vivienda

    OpenAIRE

    Arcudia Abad, Carlos Enrique; Solís Carcaño, Rómel Gilberto; González Fajardo, José Antonio

    2011-01-01

    La investigación de la productividad de la mano de obra puede ser un medio que coadyuve al incremento del nivel de vida y de las condiciones de trabajo de los obreros. En este trabajo se aplica el Modelo de los factores para el estudio de la productividad del trabajo en la industria de la construcción, en cuatro proyectos de vivienda masiva del tipo de interés social. Se realizaron mediciones de los trabajos efectuados en cuatro proyectos por sendas cuadrilla en el concepto muro a base de blo...

  10. “IMPACTO DE LA PUBLICIDAD MASIVA: SAGA FALABELLA Y LA DISCRIMINACIÓN COMO IMAGINARIO SOCIAL”

    OpenAIRE

    Chugo Yrigoyen, Renato Manuel

    2016-01-01

    En la publicidad peruana es muy notorio que existe un imaginario social que resalta con cierta fuerza, este es la discriminación racial en las campañas publicitarias masivas, el concepto de belleza está regido a rasgos físicos muy lejanos a los de un peruano promedio. Esto tomó más fuerza cuando la empresa Saga Falabella llevó al público una publicidad que indignó a más de uno, esto nos lleva a la preguntarnos ¿La publicidad peruana lleva a este imaginario social como parte de ella? Es import...

  11. La Aproximación de las Estrategias de la UE y EEUU en la Lucha contra la Proliferación de Armas de Destrucción Masiva

    Directory of Open Access Journals (Sweden)

    Milagros Álvarez

    2012-10-01

    Full Text Available El cambio en el seno de la Administración estadounidense tras las elecciones de 2008 y la consiguiente adopción de nuevos documentos estratégicos en la lucha contra la proliferación de armas de destrucción masiva suscitan nuevamente el interés de su comparación con los planteamientos defendidos por la UE, al objeto de identificar la posible emergencia de nuevos márgenes de coincidencia entre ambos actores internacionales y, con ello, el impulso a nuevos compromisos en el régimen de no proliferación. La comparación revela tres tendencias fundamentales: estancamiento en el proceso de mejora y perfeccionamiento de la regulación prevista para las armas químicas y biológicas, desarrollo selectivo del régimen de no proliferación nuclear, y consolidación de la cooperación informal y ad hoc como instrumento contra la proliferación de ADM.

  12. ABSENTISMO Y ROTACIÓN EN LA CONSTRUCCIÓN MASIVA DE VIVIENDA. EFECTO EN LA PRODUCTIVIDAD

    Directory of Open Access Journals (Sweden)

    Carlos Enrique Arcudia Abad

    2003-09-01

    Full Text Available

    El trabajo está enfocado a dos aspectos importantes y poco estudiados, y que predominan en la mano de obra de albañilería en la construcción masiva de vivienda: el absentismo y la rotación. En esta investigación se tuvo como objetivo: desarrollar una metodología para medir dichos fenómenos, realizar esta y, posteriormente, efectuar un análisis de correlación entre estos y la productividad con el fin de determinar una posible relación. El estudio se encaminó a dos niveles de organización de la mano de obra de albañilería: en la brigada y en la cuadrilla, según se tratase de todo el grupo que labora en una o más unidades de vivienda o del que desarrolla una actividad de construcción específica en las mismas. La investigación abarca dos proyectos de construcción masiva de vivienda. Los resultados obtenidos fueron cotejados con los reportes de estudios realizados en otros contextos, los cuales se basaban en índices de absentismo de la brigada en grandes proyectos de construcción.

  13. Hemorragia digestiva baja masiva en pacientes con enfermedad de Crohn Major acute bleeding in patients with Crohn's disease

    Directory of Open Access Journals (Sweden)

    M. Barreiro de Acosta

    2007-07-01

    Full Text Available Objetivo: analizar la frecuencia de las hemorragias masivas en la EC e intentar determinar sus potenciales factores de riesgo (ambientales, propios de la enfermedad y genéticos. Material y métodos: se estudió de manera retrospectiva una cohorte de 174 pacientes -103 mujeres (59% y 71 hombres (41%, edad media de 37 años- con EC, analizándose las hemorragias digestivas masivas que se habían producido en relación con su enfermedad. Se revisaron asimismo potenciales factores de riesgo como hábito tabáquico, localización de la enfermedad y presencia de mutaciones genéticas en CARD15, RTL-4 y CD14, entre otros. Resultados: tres pacientes (1,7% presentaron una hemorragia digestiva masiva que precisó intervención quirúrgica para su resolución. Esta indicación de cirugía supone el 3,4% de las cirugías en relación con la EC. Todos los pacientes eran jóvenes y su enfermedad seguía un patrón inflamatorio y estaba localizada en el íleon. No se ha evidenciado asociación estadísticamente significativa entre las hemorragias digestivas masivas y los potenciales factores de riesgo analizados. Conclusiones: la hemorragia digestiva baja masiva es una complicación poco común, aunque grave de la EC. Se trata habitualmente de pacientes con patrón inflamatorio de la enfermedad y afectación ileal. Para su diagnóstico resulta clave la asociación de endoscopia y arteriografía, y su resolución suele ser quirúrgica.Objective: we aimed at evaluating the frequency of acute severe bleeding in CD and its potential association to some risk factors, including clinical features of CD, environmental factors, and genetic alterations. Material and methods: 174 consecutive patients with CD (103 female (59% and 71 men (41%, with a mean age of 37 years were included. We analyzed all major acute lower gastrointestinal (GI hemorrhage related to CD. Potential risk factors like smoking, site of disease, and presence of gene mutations in CARD15, TLR-4, and

  14. Mortandad masiva de mesodesma mactroides (bivalvia: mactracea) en el partido de la Costa, Buenos Aires, Argentina, en septiembre 2004

    OpenAIRE

    Thompson, Gustavo; Bock, Mariana Federica Sánchez de

    2007-01-01

    La almeja amarilla Mesodesma mactroides ha sido diezmada por vários eventos de mortandad masiva a lo largo de su distribución en Brasil, Uruguay y Argentina. Este estudio evalúa y compara la concentración de As, Cd, Cr, Cu, Ni, Pb y Zn, em los tejidos de las almejas colectadas durante un evento de mortandad en Septiembre 2004 y un año después. La cuantificación de los metales se realizó por digestión ácida y posterior determinación por espectrometría. Los valores de Cd, Cu y Pb (11 ± 2, 42 ± ...

  15. Intestinal Obstruction

    Science.gov (United States)

    ... the obstruction along the intestines. Treatment Suction via nasogastric tube Fluids given by vein Surgery for strangulation Sometimes ... nose and placed in the stomach (called a nasogastric tube) or into the intestine. Suction is applied to ...

  16. Viabilidad de huevos y modelo de jaula para la cría artificial masiva de Anastrepha fraterculus (Diptera: Tephritidae

    Directory of Open Access Journals (Sweden)

    JULIANA GARCÍA

    2011-01-01

    Full Text Available El objetivo del presente trabajo fue determinar la viabilidad de huevos y el modelo de jaula apropiada para la cría artificial masiva de Anastrepha fraterculus (Wiedemann. Los resultados muestran que el periodo de máxima oviposición ocurre durante los primeros 10 días en jaulas modelo Mediana, lo cual permite obtener el volumen de huevos necesario para alimentar el pie de cría de A. fraterculus en una cría masiva. Considerando que se encontró relación positiva entre el volumen de huevos ovipositados y el porcentaje de eclosión de huevos, en un periodo de 21 días de colecta, este periodo coincide además con los valores de eclosión más altos. Entre los modelos de jaulas evaluadas: Mediana, Grande y Mission; el modelo Mediana mostró los mejores resultados al evaluar el número de huevos/hembra/día con un valor promedio de 11,4. La jaula que mostró menores resultados fue el modelo Mission, con un valor promedio de 4,6 huevos/hembra/día. Las jaulas grandes mostraron valores menores a las jaulas Medianas, pero las diferencias fueron no significativas. Los buenos valores registrados en las jaulas Medianas posiblemente se deban a la estructura de la jaula, que presentó la cara interna dividida en muchos compartimientos, lo cual mejora la distribución de las moscas adultas y previene la mortalidad temprana por hacinamiento en la base o en el techo de la jaula.

  17. Proceso asistencial de enfermeria

    OpenAIRE

    Orrega Sierra, Silvia

    1988-01-01

    El presente atículo hace resumen de los postulados teóricos de Nancy Roper, los cuales acoge como marco teórico; además se incluye en concordancia con dicho marco conceptual, la definición de diferentes actividades que comprenden los apectos biopsicosociales del ser humano. A continuación describe lo que debe comprender el proceso de atención de Enfermería según la clasificación de Yura y Walsh, plantea una serie de criterios para valorar la dependencia-independencia del individio o grupo...

  18. Procesos creativos: problemas y arte

    OpenAIRE

    Sanz Lobo, Estefania

    2003-01-01

    "CuaIes son los procesos creativos de los artistas? "Son los mismos procesos que los que se utilizan para pensar creativamente en cualquier otra area? "Pueden estimularse y mejorarse estos procesos? "Como? Estas son algunas de las preguntas que me hice en torno a la creatividad y al arte; han guiado mi inquietud investigadora en el campo de la Educacion Artfstica durante los ultimos cuatro años. Hoy puedo comenzar a proponer algunas respuestas (digo proponer porque, en este ambito ...

  19. La finalidad del proceso

    Directory of Open Access Journals (Sweden)

    Iván Alfonso Cordero Gutiérrez

    2011-07-01

    Full Text Available Resumen:El tipo de Estado que Colombia asumió desde 1991 (Estado Social de Derecho, implica que el cumplimiento de los fines estatales se comparten con la población, generando de esta forma grados de responsabilidad respecto a las cargas asumidas por ellos y el Estado para la materialización de los objetivos planteados. La satisfacción de las necesidades básicas de la población como unode los fines esenciales del Estado Social de Derecho, no escapa a este esquema, lo que determina la colaboración armónica no sólo entre las entidades y organismos del Estado sino de este, complementado con la población. Una de las necesidades básicas de la población, se refiere a la posibilidad de resolver sus conflictos haciendo uso de los mecanismos que para tal efecto tiene a su disposición, utilizando las formas de Auto tutela, Autocomposición, híbridas y de Heterocomposiciòn, que el Estado autoriza,de acuerdo a los lineamientos propios de cada mecanismo, respecto a las materias que componen los derechos sustanciales que se debaten en la relación conflictiva. Dentro de estos mecanismos de solución de conflictos, la heterocomposiciòn presenta uno llamado el proceso jurisdiccional, en donde un tercero investido de poderes específicos ejerce la jurisdicción y toma la decisión respecto al conflicto, después del agotamiento de etapas sucesivas y preclusivas que garantizan la efectiva participación, ejercicio y defensa de los derechos fundamentales y sustanciales de las partes, generando una mayor garantía de legalidad respecto a la decisión generada por ese tercero investido de plena Jurisdicción (el Juez. Por ser el proceso jurisdiccional el mecanismo más idóneo por su garantismo reglado y tecnificado, debe ser protegido, fortalecido y preferente respecto a los denominados equivalentesjurisdiccionales pues con estos el Estado pretende desplazar la competencia al momento de la resolución de los conflictos, generando un

  20. Intestine transplantation

    Directory of Open Access Journals (Sweden)

    Tadeja Pintar

    2011-02-01

    Conclusion: Intestine transplantation is reserved for patients with irreversible intestinal failure due to short gut syndrome requiring total paranteral nutrition with no possibility of discontinuation and loss of venous access for patient maintenance. In these patients complications of underlying disease and long-term total parenteral nutrition are present.

  1. Pseudo-obstrucción intestinal crónica Chronic intestinal pseudo-obstruction

    OpenAIRE

    M. T. Muñoz; J. A. Solís Herruzo

    2007-01-01

    El síndrome de pseudo-obstrucción intestinal crónica se caracteriza por la presencia de cuadros clínicos recidivantes que simulan una obstrucción intestinal pero en ausencia de proceso obstructivo anatómico. Es poco frecuente pero determina una alta morbilidad. Se origina como consecuencia de una alteración de la motilidad intestinal que no puede hacer progresar su contenido debido a la afectación de su componente muscular, neurológico o de ambos. Son más frecuentes los casos secundarios a un...

  2. Intestinal Ischemia

    Science.gov (United States)

    ... weight loss Intestinal ischemia Symptoms & causes Diagnosis & treatment Advertisement Mayo Clinic does not endorse companies or products. ... a Job Site Map About This Site Twitter Facebook Google YouTube Pinterest Mayo Clinic is a not- ...

  3. El proceso constituyente venezolano

    Directory of Open Access Journals (Sweden)

    Ricardo COMBELLAS

    2009-11-01

    Full Text Available RESUMEN: La Asamblea Nacional Constituyente permitirá redefinir el marco institucional de la república venezolana. Este proceso constituyente iniciado en 1989 aborda una etapa definitiva debido al apoyo mayoritario de los venezolanos y a que ha sido asumido como bandera por el hoy presidente Hugo Chávez.El paradigma constitucional ha tenido tropiezos originados por el populismo, el clientelismo, la corrupción, la falta de un trabajo legislativo oportuno, la falta de garantías a los derechos fundamentales, el deterioro del poder judicial y la falta de una participación política abierta.Para llevar a cabo una asamblea nacional constituyente es fundamental la participación amplia que lleve a un consenso constructivo. Es decir, se tratará de iniciar el 25 de abril una constituyente originaria que implica que su capacidad decisoria no esté sujeta a ningún poder establecido, ya que su origen es la expresión política de la soberanía popular que va a modificar el ordenamiento jurídico existente.ABSTRACT: The National Assembly Constituency will permit the redefinition of the institutional framework of the Venezuelan Republic. This fundamental process started in 1989 outlines a definitive stage due to the major support of the Venezuela people, and has been assumed as the platform of present president Hugo Chávez.The constitutional paradigm has flaws that originate from the following: populism, clientelism, corruption, the lack of timely legislative work, the lack of guarantees to basic rights, the deterioration of judicial power, and the lack of open political participation.For the National Assembly Constituency to work, extensive participation is fundamental to bring forth constructive consensus. As its origins now is the political expression of popular sovereignty that modifies the existing judicial order, it wil try to iniciate on the 25th of April a new constituency that implies that its capacity for decision making is not subject to

  4. Intestinal Coccidia

    OpenAIRE

    MJ Ggaravi

    2007-01-01

    Intestinal Coccidia are a subclass of Apicomplexa phylum. Eucoccidida are facultative heteroxenous, but some of them are monoxenous. They have sexual and asexual life cycle. Some coccidia are human pathogens, for example: Cryptosporidium: Cryptosporidiums has many species that are mammalian intestinal parasites.C. Parvum specie is a human pathogenic protozoa. Cryptosporidum has circle or ellipse shapes and nearly 4-6 mm. It is transmitted in warm seasons. Oocyst is obtained insexual life cycl...

  5. Small Intestine Disorders

    Science.gov (United States)

    ... disease Crohn's disease Infections Intestinal cancer Intestinal obstruction Irritable bowel syndrome Ulcers, such as peptic ulcer Treatment of disorders of the small intestine depends on the cause.

  6. Las técnicas de secuenciación masiva en el estudio de la diversidad biológica.

    Directory of Open Access Journals (Sweden)

    Unai López de Heredia

    2016-01-01

    Full Text Available Las técnicas de análisis genómico que se basan en la secuenciación masiva han supuesto una revolución en la última década no sólo en biomedicina o agronomía, sino también en el estudio de la diversidad biológica. Las plataformas de secuenciación de segunda y tercera generación que vienen a complementar a la tradicional secuenciación por el método Sanger, permiten analizar un gran número de individuos obteniendo una profundidad de secuenciación significativa de sus genomas o transcriptomas. Así, aunque todavía de manera incipiente, se vienen realizando estudios sobre la flora y fauna silvestre a escala poblacional, con especial énfasis en la determinación de patrones adaptativos frente a los cambios ambientales. En la presente revisión se describe la situación actual de las plataformas de secuenciación masiva, señalando sus ventajas y limitaciones para el análisis en organismos no modelo, para a continuación detallar las bases de dos de las técnicas más populares que se benefician de la secuenciación masiva (RAD-seq y RNA-seq y señalar algunos ejemplos de su uso para el estudio de la diversidad biológica.

  7. Un Protocolo Conversacional de una Entrevista de Corte Policiaco a un Detenido, Difundida en los Medios de Comunicación Masiva

    OpenAIRE

    Vázquez Laslop María Eugenia

    2017-01-01

    El 30 de agosto de 2010 la Policía Federal mexicana detuvo a uno de los capos del narcotráfico más buscados del momento, Édgar Valdez Villarreal, “La Barbie”. Durante los primeros días de septiembre la Secretaría de Seguridad Pública difundió en los medios de comunicación masiva fragmentos de una entrevista al detenido realizada el 31 de agosto, que seguía un formato en apariencia oficial e institucional. El objetivo de este artículo es describir la entrevista a modo de protocolo en términos ...

  8. Las Armas de Destrucción Masiva y la Estrategia Global de Seguridad de la Unión Europea

    OpenAIRE

    Monica Miranzo

    2016-01-01

    La proliferación de Armas de Destrucción Masiva (ADM), Nucleares, Biológicas y Químicas (NBQ) es una de las principales amenazas a la seguridad que enfrenta la comunidad internacional en la actualidad Sin embardo la nueva Estrategia Global de Seguridad de 2016 plantea la cuestión de la no proliferación de ADM sólo de forma tangencial, sin abordar la amenaza directamente, un problema fundamental en la seguridad. Esto supone un claro paso atrás para la seguridad común europea, que ha optado por...

  9. Florecimiento de microalgas relacionado con mortandad masiva de peces en el complejo lagunar Ciénaga Grande de Santa Marta, Caribe colombiano

    OpenAIRE

    Mancera-P., José E.; Vidal-V., Luis A.

    1994-01-01

    Entre los meses de julio y agosto de 1994 un fenómeno discontinuo de muerte masiva de peces se registró en aguas del complejo lagunar de la Ciénaga Grande de Santa Marta, Colombia. El primer evento se presentó del 15 al 19 de julio, el segundo alrededor del día 20 de agosto y el tercero entre el 26 y 31 del mismo mes. La presencia en altas concentraciones de la cianofita filamentosa Cf. Anabaenopsis sp., registrada en la literatura como altamente tóxica, podría estar relacionada con las causa...

  10. Nuevo enfoque para el estudio de la productividad en la construcción masiva de vivienda

    Directory of Open Access Journals (Sweden)

    Carlos Enrique Arcudia Abad

    2002-01-01

    Full Text Available La investigación de la productividad de la mano de obra puede ser un medio que coadyuve al incremento del nivel de vida y de las condiciones de trabajo de los obreros. En este trabajo se aplica el Modelo de los factores para el estudio de la productividad del trabajo en la industria de la construcción, en cuatro proyectos de vivienda masiva del tipo de interés social. Se realizaron mediciones de los trabajos efectuados en cuatro proyectos por sendas cuadrilla en el concepto muro a base de bloques de concreto. Los datos obtenidos se analizaron con apoyo en la teoría para la evaluación de la productividad de la mano de obra, que se fundamenta en el concepto de la línea base de cada proyecto, la cual está relacionada básicamente con la complejidad del diseño. Esta relación se establece por medio de un modelo de regresión. Se definen dos índices con el objeto de medir la calidad en la ejecución de los trabajos: el índice de días de bajo ritmo (ISR y el índice de administración de proyecto (IAP. El primero mide el porcentaje de días de trabajo anormal o de baja productividad, y el segundo remueve la influencia del diseño en la medida de la productividad para mostrar el efecto de la organización y administración de la obra. Se desarrolla una metodología para la comparación de los cuatro proyectos, usando las curvas de probabilidad acumulada de IBR e lAR encontrándose que un proyecto dado puede presentar mejor desempeño en su ejecución, a pesar de tener cuantitativamente menor productividad, considerando la complejidad del trabajo por ejecutar.

  11. DIAGNÓSTICO MOLECULAR DE ENFERMEDADES GENÉTICAS: DEL DIAGNÓSTICO GENÉTICO AL DIAGNÓSTICO GENÓMICO CON LA SECUENCIACIÓN MASIVA

    Directory of Open Access Journals (Sweden)

    Sonia Santillán-Garzón Md., PhD

    2015-07-01

    La secuenciación masiva está cambiando el modelo de diagnóstico molecular de los afectos, sin embargo, los médicos y profesionales de la salud se enfrentan al dilema de la selección del método más eficiente, con el menor coste sanitario y con la mayor precisión de sus resultados. El objetivo de este trabajo es revisar la tecnología de secuenciación masiva y definir las ventajas y los problemas en su utilización.

  12. Proyecto de reforma del Proceso Penal

    Directory of Open Access Journals (Sweden)

    Beatriz Scapusio

    2014-04-01

    Full Text Available El Anteproyecto de Código de Proceso PenalExpositora: Beatriz ScapusioLa Imputabilidad Aportes dogmáticos para un tema clave de la responsablidad penalExpositor: Dardo Preza RestucciaEstructuras procesales en el proceso de conocimiento y en el proceso de ejecuciónExpositora: Raquel Landeira

  13. El proceso emprendedor en Chile

    OpenAIRE

    José Miguel Benavente

    2004-01-01

    Este estudio analiza los factores que afectan en forma positiva y negativa el proceso de creación de emprendimientos dinámicos en Chile. Se basa en una encuesta a 200 empresas jóvenes, la cual es parte de una muestra de casi 2000 empresas de América Latina. El presente estudio se enfoca básicamente en el segmento de nuevos emprendimientos existentes en Chile.

  14. Debido proceso, sistemas y reforma del proceso penal

    Directory of Open Access Journals (Sweden)

    Teresa Armenta Deu

    2015-03-01

    Full Text Available Este artículo se propone examinar los modelos de procesos penales de los movimientos de reforma que se establecieron en las últimas décadas del siglo XX, en los países iberoamericanos. Para ello, primero se enfatiza las características históricas de cada sistema, poniendo de relieve la importancia de no confundir el acusatorio con el adversarial, rechazando la coincidencia entre los sistemas actuales y mixto inquisitivo histórico. Apoya la importancia de la igualdad de armas y e del contradictoria en la búsqueda de un equilibrio entre los modelos de procedimiento.

  15. Debido proceso, sistemas y reforma del proceso penal

    OpenAIRE

    Teresa Armenta Deu

    2015-01-01

    Este artículo se propone examinar los modelos de procesos penales de los movimientos de reforma que se establecieron en las últimas décadas del siglo XX, en los países iberoamericanos. Para ello, primero se enfatiza las características históricas de cada sistema, poniendo de relieve la importancia de no confundir el acusatorio con el adversarial, rechazando la coincidencia entre los sistemas actuales y mixto inquisitivo histórico. Apoya la importancia de la igualdad de armas y e del contradic...

  16. Optimizaión de un protocolo para el cultivo in vitro y la micropropagación masiva del llantén (Plantago major

    Directory of Open Access Journals (Sweden)

    Giovanni Garro M.

    2009-01-01

    Full Text Available Llantén (P. major posee propiedades medicinales antiinflamatorias y cicatrizantes que han sido aprovechadas en muchas latitudes desde épocas remotas. Los estudios del cultivo in vitro de esta especie son escasos, a pesar de las ventajas que este tipo de técnicas presenta en especies de uso medicinal. En este trabajo se logró desarrollar un protocolo para el establecimiento y la reproducción masiva in vitro del llantén. Se estableció un protocolo de desinfección de semillas y se obtuvo plántulas germinadas in vitro que se utilizaron como fuente de explantes para la fase de micropropagación masiva. Se evaluó el cultivo de ápices en medios de cultivo con sales y vitaminas de M & S (1962 al 100% y al 50%, suplementados con los siguientes reguladores de crecimiento: 1,2mg/l de ANA (Ácido naftalenacético, 0,6 mg/l y 0,4 mg/l de BAP (Bencil amino purina y 1mg/l de TDZ (Tidiazurón en diferentes combinaciones. Los mejores resultados en la inducción de brotes fueron obtenidos en 14,9 brotes promedio por explante en el medio con las sales y vitaminas M & S (1962 reducidas al 50% de su concentración y sin reguladores de crecimiento. Con este tratamiento, un total de 150 vitroplantas provenientes de distintos tratamientos han sido llevadas a condiciones de invernadero con un 100% de sobrevivencia.

  17. Intestinal pseudo-obstruction

    Science.gov (United States)

    Primary intestinal pseudo-obstruction; Acute colonic ileus; Colonic pseudo-obstruction; Idiopathic intestinal pseudo-obstruction; Ogilvie syndrome; Chronic intestinal pseudo-obstruction; Paralytic ileus - pseudo-obstruction

  18. Intestinal myiasis

    Directory of Open Access Journals (Sweden)

    U S Udgaonkar

    2012-01-01

    Full Text Available Purpose: Intestinal myiasis is a condition when the fly larvae inhabit the gastrointestinal tract and are passed out in faeces. This type of infestation results when eggs or larvae of the fly, deposited on food are inadvertently taken by man. They survive the unfavourable conditions within the gastrointestinal tract and produce disturbances, which may vary from mild to severe. The condition is not uncommon and is often misdiagnosed as pinworm infestation. Correct diagnosis by the clinical microbiologist is important to avoid unnecessary treatment. Materials and Methods: We had 7 cases of intestinal myiasis. In 2 cases the larvae were reared to adult fly in modified meat and sand medium (developed by Udgaonkar. This medium is simple and can be easily prepared in the laboratory. Results: Of the 7 larvae, 5 were Sarcophaga haemorrhoidalis, 1 Megaselia species and 1 was identified as Muscina stabulans. Conclusions: S. haemorrhoidalis was the commonest maggot involved. A high index of suspicion is required for clinical diagnosis when the patient complains of passing wriggling worms in faeces for a long period without any response to antihelminthics. The reason for long duration of illness and recurrence of infestation is baffling. The nearest to cure was colonic wash. We feel prevention is of utmost importance, which is to avoid eating food articles with easy access to flies.

  19. La perestroika, un proceso direccional

    Directory of Open Access Journals (Sweden)

    Edgardo Erazo Obando

    1990-04-01

    Full Text Available El artículo presenta una visión diferente de las implicaciones, efectos y resultados  de un proceso histórico como lo es la Perestroika. Este término acuñado como propio en nuestra cultura occidental, ha representado para la Unión  Soviética y sus “países asociados” la transformación de los principios filosóficos, económicos, políticos y organizacionales. Es importante reconocer que el “cambio” cuando se realiza  en forma amplia produce en cualquier institución u organización el “fenómeno de resistencia”, para la Perestroika, este hecho  no ha sido extraño y, se ha constituido en uno de los grandes problemas a vencer, toda vez, que de él depende el éxito o fracaso del proceso de reestructuración. De todas formas, la mayor incidencia la recibirá el sector empresarial, que deberá transformarse a pasos de gigante para lograr niveles de eficiencia y productividad que garanticen el desarrollo de la política socio – económica del nuevo plan.  Ojalá esta transformación implique para la administración de una nueva teoría direccional

  20. Intestinal Failure (Short Bowel Syndrome)

    Science.gov (United States)

    Intestinal Failure (Short Bowel Syndrome) What is intestinal failure? Intestinal failure occurs when a significant portion of the small ... intestine does. Who is at risk for intestinal failure? N Babies (usually premature) who have had surgery ...

  1. Optimización y automatización del proceso de compra para tiendas de consumo masivo a través de tecnología móvil y jee

    OpenAIRE

    Iñiguez Jarrín, Carlos Efraín

    2013-01-01

    Es un sistema de análisis de adquisición de bienes o servicios, a través de la web, calidad, precio, lugar, promociones y más en cualquier parte del mundo. El proyecto de Gestión de Compras Masivas se compone de dos aplicaciones; una para ser instalada y ejecutada en teléfonos móviles con plataforma Android y otra basada en web, desarrollada en plataforma JEE que es en sí la administración de la solución completa. La solución está diseñada para optimizar y automatizar el proceso de comp...

  2. Temperature and massive fish deaths in southern South America Temperatura y mortandades masivas de peces en el sur de Sudamérica

    Directory of Open Access Journals (Sweden)

    M. Jimena González Naya

    2011-12-01

    Full Text Available Based on a compilation of data on massive fish deaths occurred in southern South America during the Twentieth Century, we assessed the importance of climatic variables on these phenomena. We found a strong relationship (R² =0.68 between these massive fish deaths and the mean monthly air temperature. Along the annual temperature range there is a central range (14.6° C to 20.0° C, where the probabilities that a fish community suffers massive deaths is very low. Its central point (17.3° C is very close to the mean annual value (17.2° C of air temperature variation. We considered this agreement as corroboration at community level of Pianka’s theory on physiological optima. This relationship allows to monitoring the influence of climate changes, because the environmental variation and the zones of mortality and no mortality will change with predicted changes of the mean monthly values of air temperature.Basado en la recopilación de datos de mortandades masivas de peces ocurridas en el sur de Sud América durante el Siglo XX, se evaluó la importancia de las variables climáticas en estos fenómenos. Se encontró una fuerte relación (R² =0,68 con la temperatura media mensual del aire. A lo largo del rango de temperaturas anuales hay un rango central (14,6° C a 20,0° C donde las probabilidades que una comunidad de peces sufra mortandades masivas son muy bajas. Su punto central (17,3° C es muy cercano al valor medio anual (17,2° C de la variación de temperatura del aire. Se considera esto como una corroboración a nivel de comunidad de la teoría del óptimo fisiológico de Pianka. Esta relación permite monitorear la influencia de los cambios climáticos, dado que la variación ambiental y las zonas de mortalidad y no mortalidad cambiarán con las variaciones predichas de los valores medios mensuales de la temperatura del aire.

  3. ENFERMEDAD PSICOGÉNICA MASIVA DESPUÉS DE UNA CAMPAÑA DE VACUNACIÓN EPISODIOS ANTERIORES Y APROXIMACIÓN AL CASO COLOMBIANO

    Directory of Open Access Journals (Sweden)

    Alfredo Jácome Roca

    2014-10-01

    Full Text Available Al revisar en la base de datos PubMed los términos “enfermedad psicogénica masiva” y “vacunación”, solo aparecen ocho referencias. Curiosamente todos esos casos asociados con vacunación masiva –con excepción de un brote acaecido en España con hepatitis B - se presentaron en países orientales como China y Taiwan y el virus de influenza AH1N1, Irán después de toxoide tetánico, Vietnam con vacuna oral de cólera y Jordania con un toxoide diftérico-tetánico. No se refiere la literatura a casos asociados a vacunación contra el VPH. Si se solo se investiga el término “enfermedad psicogénica masiva”, las referencias ascienden a 78, ya que estos fenómenos han venido siendo informados desde 1374, refiriéndose a bailes compulsivamente contagiosos o a risa contagiosa, y se asocian con situaciones reales o hasta cierto punto imaginarias que pueden crear pánico en una comunidad.

  4. LOS NIVELES DE MICROCONTAMINANTES ORGÁNICOS EXPLICAN UNA MUERTE MASIVA DE PECES EN EL RÍO ATOYAC, PUEBLA, MÉXICO

    Directory of Open Access Journals (Sweden)

    Amado E. Navarro

    2017-01-01

    Full Text Available Se reportó una muerte masiva de peces en el río Atoyac, presumiendo como causa el vertido de algún contaminante químico muy tóxico. El análisis de muestras de agua, sedimentos y tejidos, mostró una baja concentración de oxígeno disuelto y elevadas de amonio y de nitritos en el río el día del incidente, probables causas directas de la muerte de los peces. Por cromatografía de gases/espectrometría de masas, no se detectaron contaminantes persistentes pero sí, concentraciones elevadas de microcontaminantes orgánicos antrópicos, lo cual indica un vertido de residuos municipales al cauce de la corriente, causa indirecta de la muerte de los peces. Las concentraciones de coprostanol y epicoprostanol indican la presencia de heces de mamíferos, incluidas las de rumiantes, en el vertido. Los resultados obtenidos muestran la utilidad de determinar las concentraciones de los microcontaminantes orgánicos para esclarecer las causas de estos incidentes.

  5. Procesos de cambio en organizaciones productivas

    OpenAIRE

    Laverde Carmona, Myriam Patricia

    2008-01-01

    El presente estudio de carácter exploratorio, basado en procesos de cambios en organizaciones productivas, involucra cuatro organizaciones altamente significativas de diferentes sectores de Medellín -- Estas Organizaciones han incursionado en procesos de cambio, donde los trabajadores jugaron un papel importante como partícipes del proceso y de las prácticas realizadas, destacando la participación e integración de los diferentes niveles jerárquicos de la organización en la planeación de activ...

  6. Procesos infinitos inherentes a la integral definida

    OpenAIRE

    Cuida Gómez, María Astrid

    2016-01-01

    Esta investigación está centrada en la comprensión de procesos infinitos asociados a la integral definida y el objetivo principal es detectar y caracterizar la comprensión de procesos infinitos que subyacen a este concepto. De este objetivo se derivan otros más específicos que han guiado la búsqueda de elementos de comprensión relacionados con los procesos infinitos vinculados a la integral definida que inciden en su comprensión. Los análisis implicativo y de similaridad han permitido identi...

  7. Intestinal microbiome landscaping

    NARCIS (Netherlands)

    Shetty, Sudarshan A.; Hugenholtz, Floor; Lahti, Leo; Smidt, Hauke; Vos, de Willem M.

    2017-01-01

    High individuality, large complexity and limited understanding of the mechanisms underlying human intestinal microbiome function remain the major challenges for designing beneficial modulation strategies. Exemplified by the analysis of intestinal bacteria in a thousand Western adults, we discuss

  8. Small Intestine Cancer Treatment

    Science.gov (United States)

    ... all of an organ that contains cancer. The resection may include the small intestine and nearby organs (if the cancer has spread). The doctor may remove the section of the small intestine that contains cancer and perform an anastomosis (joining the cut ends of the intestine together). ...

  9. Un Protocolo Conversacional de una Entrevista de Corte Policiaco a un Detenido, Difundida en los Medios de Comunicación Masiva

    Directory of Open Access Journals (Sweden)

    Vázquez Laslop María Eugenia

    2017-11-01

    Full Text Available El 30 de agosto de 2010 la Policía Federal mexicana detuvo a uno de los capos del narcotráfico más buscados del momento, Édgar Valdez Villarreal, “La Barbie”. Durante los primeros días de septiembre la Secretaría de Seguridad Pública difundió en los medios de comunicación masiva fragmentos de una entrevista al detenido realizada el 31 de agosto, que seguía un formato en apariencia oficial e institucional. El objetivo de este artículo es describir la entrevista a modo de protocolo en términos del mecanismo de la interacción verbal entre el entrevistador y el entrevistado y reflexionar acerca de dicho formato según el modelo jurídico de la entrevista policiaca, así como de la configuración de la identidad del entrevistado por parte de la Secretaría de Seguridad Pública. Se caracteriza esta entrevista policiaca desde tres perspectivas: una jurídica, en materia penal, una pragmática, de acuerdo con los parámetros conversacionales propios de cualquier interacción verbal y de los conceptos de fachada, identidad y estigma en la presentación de la persona, y una gramatical, respecto de las formas de las preguntas en las entrevistas semi-estructuradas. Se reflexiona acerca de la difusión de este material en los medios de comunicación como estrategia de propaganda política.

  10. Cría masiva y uso de ninfas de Rhodnius pallescens, Barber, 1932 (Hemiptera, Reduviidae, Triatominae para ensayos biológicoso

    Directory of Open Access Journals (Sweden)

    Mónica Flórez M

    2015-04-01

    Full Text Available Introducción: Rhodnius pallescens es una especie silvestre que hace intrusión a las viviendas en zonas en las cuales se han presentado brotes de Chagas agudo en Colombia; y para el estudio de sus características biológicas y el monitoreo de la susceptibilidad o resistencia de poblaciones de campo a insecticidas, se requiere del uso de una gran cantidad de insectos mantenidos en el laboratorio. Objetivo: Establecer condiciones de cría de ninfas de R. pallescens que permitan su mejor aprovechamiento en ensayos biológicos. Metodología: Se utilizó una cepa de laboratorio de R. pallescens proveniente de San Martin (Cesar, Colombia y se realizaron bioensayos para: estimar el tiempo de alimentación, establecer condiciones de cría, estimar tiempos de desarrollo ninfal y comparar la fecundidad usando dos fuentes de alimentación y varios tipos de soporte. Resultados: 60 minutos de ofrecimiento de alimento permite la alimentación de 95% de las ninfas. El promedio de oviposición diario/hembra fue de 2,7 huevos y no varío significativamente con el consumo de sangre de gallina o ratón. La duración promedio del ciclo de vida desde huevo hasta el estadio ninfa-V fue de 128,6 días. El uso de cartulina negra y plumas dentro de los frascos de cría mejora la oviposición. Ninfas-V alimentadas desde ninfa-I y pesadas a los 5 o 6 días permite un aprovechamiento del 89% de las ninfas. Conclusiones: Los resultados de este trabajo brindan conocimiento para la cría masiva y el uso de ninfas de Rhodnius pallescens en ensayos biológicos.

  11. Microbiota intestinal, probióticos y prebióticos

    OpenAIRE

    Carlos David Castañeda Guillot

    2017-01-01

    La microbiota intestinal es el elemento fundamental del “Ecosistema Intestinal”, cuyas acciones tienen un efecto beneficioso para la salud, al participar de forma activa en los procesos de digestión de nutrientes asociado a sus mecanismos sobre la homeostasis y la inmunidad del intestino. Los probióticos y prebióticos juegan un rol decisivo en la modulación de la microbiota intestinal y han demostrado sus beneficios para el tratamiento de distintas enfermedades intestinales y extra-intestinal...

  12. Gastric and intestinal surgery.

    Science.gov (United States)

    Fossum, Theresa W; Hedlund, Cheryl S

    2003-09-01

    Gastric surgery is commonly performed to remove foreign bodies and correct gastric dilatation-volvulus and is less commonly performed to treat gastric ulceration or erosion, neoplasia, and benign gastric outflow obstruction. Intestinal surgery, although commonly performed by veterinarians, should never be considered routine. The most common procedures of the small intestinal tract performed in dogs and cats include enterotomy and resection/anastomosis. Surgery of the large intestine is indicated for lesions causing obstruction, perforations, colonic inertia, or chronic inflammation.

  13. El proceso de henificación

    OpenAIRE

    Callejo Ramos, Antonio; Diaz Barcos, Virginia

    2004-01-01

    En este capítulo se describe el proceso de henificación y, por tanto, todos los pasos que llevan a que el forraje segado pierda la cantidad de agua suficiente para poder ser conservado con las menores pérdidas nutritivas posibles. Asimismo, se analizan las causas de las pérdidas de valor alimenticio que el forraje experimenta desde el estado verde original. Durante el proceso que conduce a la formación del heno se experimentan una serie de modificaciones en la composición quími...

  14. Intestinal parasites and tuberculosis

    Directory of Open Access Journals (Sweden)

    Anuar Alonso Cedeño-Burbano

    2017-10-01

    Conclusions: The available evidence was insufficient to affirm that intestinal parasites predispose to developing tuberculous. The studies carried out so far have found statistically insignificant results.

  15. adhesive intestinal obstruction

    African Journals Online (AJOL)

    2006-06-01

    Jun 1, 2006 ... ABSTRACT. Background: Adhesions after abdominal and pelvic surgery are a major cause of intestinal obstruction in the western world and the pathology is steadily gaining prominence in our practice. Objective: To determine the magnitude of adhesive intestinal obstruction; to determine the types.

  16. Intestinal Barrier and Behavior.

    Science.gov (United States)

    Julio-Pieper, M; Bravo, J A

    2016-01-01

    The intestinal barrier function contributes to gut homeostasis by modulating absorption of water, electrolytes, and nutrients from the lumen into the circulation while restricting the passage of noxious luminal substances and microorganisms. Chronic conditions such as rheumatoid arthritis, inflammatory bowel disease, and celiac disease are associated to intestinal barrier dysfunction. Here, the hypothesis is that a leaky intestinal wall allowing for indiscriminate passage of intraluminal compounds to the vascular compartment could in turn lead to systemic inflammation. An increasing number of studies are now investigating the association between gut permeability and CNS disorders, under the premise that translocation of intestinal luminal contents could affect CNS function, either directly or indirectly. Still, it is unknown whether disruption of intestinal barrier is a causative agent or a consequence in these situations. Here, we discuss the latest evidence pointing to an association between increased gut permeability and disrupted behavioral responses. © 2016 Elsevier Inc. All rights reserved.

  17. Mycotoxins and the intestine

    Directory of Open Access Journals (Sweden)

    Leon Broom

    2015-12-01

    Full Text Available Fungal biochemical pathways can yield various compounds that are not considered to be necessary for their growth and are thus referred to as secondary metabolites. These compounds have been found to have wide ranging biological effects and include potent poisons (mycotoxins. Mycotoxins invariably contaminate crops and (thus animal feeds. The intestine is the key link between ingested mycotoxins and their detrimental effects on the animal. Effects on the intestine, or intestinal environment, and immune system have been reported with various mycotoxins. These effects are almost certainly occurring across species. Most, if not all, of the reported effects of mycotoxins are negative in terms of intestinal health, for example, decreased intestinal cell viability, reductions in short chain fatty acid (SCFA concentrations and elimination of beneficial bacteria, increased expression of genes involved in promoting inflammation and counteracting oxidative stress. This challenge to intestinal health will predispose the animal to intestinal (and systemic infections and impair efficient digestion and absorption of nutrients, with the associated effect on animal productivity.

  18. Intestinal solute carriers

    DEFF Research Database (Denmark)

    Steffansen, Bente; Nielsen, Carsten Uhd; Brodin, Birger

    2004-01-01

    A large amount of absorptive intestinal membrane transporters play an important part in absorption and distribution of several nutrients, drugs and prodrugs. The present paper gives a general overview on intestinal solute carriers as well as on trends and strategies for targeting drugs and...... membrane transporters in the small intestine in order to increase oral bioavailabilities of drug or prodrug, the major influence on in vivo pharmacokinetics is suggested to be dose-dependent increase in bioavailability as well as prolonged blood circulation due to large capacity facilitated absorption...

  19. Intestinal solute carriers

    DEFF Research Database (Denmark)

    Steffansen, Bente; Nielsen, Carsten Uhd; Brodin, Birger

    2004-01-01

    membrane transporters in the small intestine in order to increase oral bioavailabilities of drug or prodrug, the major influence on in vivo pharmacokinetics is suggested to be dose-dependent increase in bioavailability as well as prolonged blood circulation due to large capacity facilitated absorption......A large amount of absorptive intestinal membrane transporters play an important part in absorption and distribution of several nutrients, drugs and prodrugs. The present paper gives a general overview on intestinal solute carriers as well as on trends and strategies for targeting drugs and...

  20. Modernización del proceso administrativo

    Directory of Open Access Journals (Sweden)

    Carlos Martínez Fajardo

    1993-01-01

    Full Text Available En el presente artículo se pretende cuestionar la idea de que la Teoría Administrativa contempla un proceso administrativo rígido y obsoleto, imposible de aplicar en la práctica de la gerencia. Por el contrario, se sostiene y se demuestra que la teoría ha continuado estudiando y desarrollando el problema de las funciones de la gerencia moderna del año 2000.

  1. procesos de alta temperatura en pymes

    Directory of Open Access Journals (Sweden)

    ANDRÉS AMELL

    2007-01-01

    Full Text Available La búsqueda de tecnologías de calentamiento que reduzcan el consumo de combustible, disminuyan las emisiones contaminantes y mejoren la productividad de los procesos y calidad de los productos en procesos de alta temperatura, ha motivado la investigación y desarrollo tecnológico de sistemas térmicos. En este contexto el artículo presenta los resultados del proyecto “Desarrollo y Evaluación de un Sistema de Combustión Autoregenerativo y Radiante para Procesos de Alta Temperatura en Pequeñas y Medianas Empresas PyMES”, presentando la configuración, funcionamiento, caracterización, parámetros de operación y comportamiento de un prototipo desarrollado que opera con 28 kW de potencia térmica con base al poder calorífico inferior, factores de aireación de 1.05 y 1.20 y temperaturas de precalentamiento de aire hasta de 700ºC.

  2. Perfeccionamiento del proceso de servicio posventa

    Directory of Open Access Journals (Sweden)

    Nivian Montes de Oca Martínez

    Full Text Available Introducción : la producción de medicamentos requiere de una exigente política de calidad que tenga la finalidad de salvaguardar los intereses del paciente, la sociedad y el Estado. Uno de los procesos más variable dentro del ciclo de vida de un producto y con requisitos muy específicos para el caso de los medicamentos es el servicio posventa. Objetivo: perfeccionar el proceso de servicio posventa de los productos para uso humano que comercializa el Centro Nacional de Sanidad Agropecuaria. Métodos: el estudio se sustenta en la aplicación de herramientas de calidad, como son: diagrama causa-efecto, tormenta de ideas, lista de chequeo, representación de los problemas detectados y aplicación de la metodología planificar-hacer-verificar-actuar. Resultados : se logró identificar a los subprocesos de atención al cliente, competencia, distribución, garantía, adiestramiento para el uso, quejas y reclamaciones, retiro de productos y farmacovigilancia como los factores principales que caracterizan al proceso. Se definieron y evaluaron los requisitos de cada uno de ellos; se obtuvo solo el 54,5 % de su cumplimiento. El diseño e implementación de un plan de mejora, permitió el perfeccionamiento del proceso, con un cumplimiento del 100 % de los requisitos diseñados. Destacan el rediseño de las funciones, responsabilidades, interrelaciones, entradas, salidas, recursos, sistema de procedimientos y registros, con énfasis en subprocesos tan específicos y complejos como la distribución, retiro de productos y la farmacovigilancia. Conclusiones: se aportan indicadores para evaluar el desempeño y facilitar la toma de decisiones y administración más eficiente del proceso, que elevan el nivel de satisfacción de los clientes. Estos resultados contribuyen a mejorar el servicio posventa de los productos con interés comercial y al cumplimiento de los requisitos de las buenas prácticas de fabricación de medicamentos.

  3. El papel de la densidad y la proporción sexual de adultos en la fecundidad de Diatraea saccharalis (Lepidoptera: Crambidae en jaulas de cría masiva

    Directory of Open Access Journals (Sweden)

    Pilar MEDINA PEREYRA

    2016-01-01

    Full Text Available La cría de insectos para control biológico aumentativo requiere conocer los factores que afectan la fecundidad para optimizar la producción masiva. En ge - neral, las prácticas empleadas se basan en los resultados de experiencias exitosas. Sin embargo, en muchos casos la verificación de esas prácticas en condiciones dis - tintas a las de su origen carece de soporte cuantitativo publicado y suele pasar por alto la variación derivada del manejo de los operarios (condición estándar. El ob - jetivo de este trabajo es evaluar la fecundidad del barrenador de la caña de azúcar Diatraea saccharalis Fabricius, en función del número de adultos y de la proporción sexual (número de hembras / número de adultos en jaulas de cría, en condiciones de producción estándar. En 25 jaulas se registraron número y sexo de las mariposas y número de huevos obtenido. Los resultados mostraron que la fecundidad óptima se obtiene con valores intermedios de densidad y con proporción sexual sesgada a machos. Se sugiere que el control conjunto de densidad y proporción sexual incre - menta la eficiencia en las posturas de huevos. El presente trabajo es el primero en cuantificar ambos factores en condiciones de cría masiva y revela que las prácticas comúnmente extendidas necesitan de estudios de mayor profundidad.

  4. Pseudo-obstrucción intestinal crónica Chronic intestinal pseudo-obstruction

    Directory of Open Access Journals (Sweden)

    M. T. Muñoz

    2007-02-01

    Full Text Available El síndrome de pseudo-obstrucción intestinal crónica se caracteriza por la presencia de cuadros clínicos recidivantes que simulan una obstrucción intestinal pero en ausencia de proceso obstructivo anatómico. Es poco frecuente pero determina una alta morbilidad. Se origina como consecuencia de una alteración de la motilidad intestinal que no puede hacer progresar su contenido debido a la afectación de su componente muscular, neurológico o de ambos. Son más frecuentes los casos secundarios a un proceso sistémico pero cada vez se describen más cuadros debidos a la afectación primaria de dichos componentes. El desarrollo de técnicas manométricas e histológicas más específicas ha permitido aclarar la patogenia de algunos de estos síndromes, entre los que se incluyen las manifestaciones paraneoplásicas y las enfermedades mitocondriales. La expresión clínica es variable y depende de la causa y de la localización y extensión de la afectación. El diagnóstico de esta entidad es habitualmente difícil lo que origina que a estos pacientes se les practiquen cirugías innecesarias, se les etiquete como enfermos psiquiátricos y el diagnóstico se realice varios años después del inicio de los síntomas. El tratamiento se dirige a mejorar los síntomas y a mantener su estado nutricional mediante medidas dietético-nutricionales, fármacos y actitudes endoscópico-quirúrgicas. La complejidad de estos enfermos aconseja su seguimiento multidisciplinar.Chronic intestinal pseudo-obstruction (CIPO is a syndrome characterized by the presence of recurrent episodes of clinical intestinal obstruction in the absence of obstructive lesions. Although this syndrome is rare, it causes a high morbidity. It is caused by a disturbance of the intestinal motility, that results in a failure of the progression of the intestinal content. Basically, the failure of the intestinal motility is a consequence of muscular disorder, neurological disorder or both

  5. La eficiencia procesal y el debido proceso

    Directory of Open Access Journals (Sweden)

    Nicolás Ignacio Ariel Carrasco Delgado

    2017-07-01

    Full Text Available El presente artículo se enmarca en la tradición del Análisis Económico del Derecho Procesal. Al respecto, se critica el tratamiento de minimización de los costos procesales relevantes que ha motivado a los autores del Law and Economics. A partir de dicha crítica se formula un tratamiento de óptimo de costos procesales para el legislador, resguardando en todo caso las exigencias del debido proceso, que opera con poder de veto respecto de aquellos óptimos que pudieran vulnerar tales exigencias.

  6. Proceso de Trabajo y Sindicalismo Universitario

    Directory of Open Access Journals (Sweden)

    Jaime Puyana Ferreira

    2000-01-01

    Full Text Available El presente texto versa sobre el carácter específico del proceso de trabajo en las instituciones universitarias. A la luz de la diferenciación entre trabajo productivo e improductivo elaborada por Marx, se sostiene que la labor de las universidades públicas es de tipo improductivo, en el sentido de que, al menos en el corto plazo, no contribuye a la obtención de ganancias. Esto hace que los sindicatos en dichas instituciones carezcan de poder para lograr incrementos en los salarios, que se aparten de las políticas establecidas por el gobierno.

  7. Errancias: la perspectiva de los procesos subjetivos

    Directory of Open Access Journals (Sweden)

    David Maldavsky

    1999-04-01

    Full Text Available Desde la perspectiva de los procesos subjetivos, el nomadismo (con o sin metas conduce a prestar atención al nexo con lo diverso, a la apropiación identificatoria o el repudio de los orígenes somáticos, las cuestiones ligadas con el multilingüismo, con la transmisión intergeneracional de los traumas y de las migraciones simbólicas de elementos correspondientes a lenguajes del erotismo que arraigan en los receptores al evocar relaciones de similitud o de complementariedad.

  8. ERRANCIAS: LA PERSPECTIVA DE LOS PROCESOS SUBJETIVOS

    OpenAIRE

    David Maldavsky

    1999-01-01

    Desde la perspectiva de los procesos subjetivos, el nomadismo (con o sin metas) conduce a prestar atención al nexo con lo diverso, a la apropiación identificatoria o el repudio de los orígenes somáticos, las cuestiones ligadas con el multilingüismo, con la transmisión intergeneracional de los traumas y de las migraciones simbólicas de elementos correspondientes a lenguajes del erotismo que arraigan en los receptores al evocar relaciones de similitud o de complementariedad.

  9. ERRANCIAS: LA PERSPECTIVA DE LOS PROCESOS SUBJETIVOS

    Directory of Open Access Journals (Sweden)

    David Maldavsky

    1999-01-01

    Full Text Available Desde la perspectiva de los procesos subjetivos, el nomadismo (con o sin metas conduce a prestar atención al nexo con lo diverso, a la apropiación identificatoria o el repudio de los orígenes somáticos, las cuestiones ligadas con el multilingüismo, con la transmisión intergeneracional de los traumas y de las migraciones simbólicas de elementos correspondientes a lenguajes del erotismo que arraigan en los receptores al evocar relaciones de similitud o de complementariedad.

  10. Reflexiones sobre el proceso salud-enfermedad

    OpenAIRE

    Velosa A., Lyla Piedad

    2010-01-01

    Desde que el individuo, las familias, las comunidades comenzaron a distinguir entre lo sano y lo enfermo, se inició un proceso de búsqueda de explicación, si se quiere de definición de los dos fenómenos. Desde entonces el hombre ha hecho enormes aportes en el plano del conocimiento de la naturaleza, de la sociedad y del pensamiento; descubriendo leyes, haciendo generalizaciones, que han revolucionado el desarrollo de sus costumbres y visión del mundo.

  11. Reflexiones sobre el proceso salud-enfermedad

    Directory of Open Access Journals (Sweden)

    Velosa A. Lyla Piedad

    1991-12-01

    Full Text Available

    Desde que el individuo, las familias, las comunidades comenzaron a distinguir entre lo sano y lo enfermo, se inició un proceso de búsqueda de explicación, si se quiere de definición de los dos fenómenos. Desde entonces el hombre ha hecho enormes aportes en el plano del conocimiento de la naturaleza, de la sociedad y del pensamiento; descubriendo leyes, haciendo generalizaciones, que han revolucionado el desarrollo de sus costumbres y visión del mundo.

  12. Diagnosis of intestinal and extra intestinal amoebiasis

    International Nuclear Information System (INIS)

    Lopez, Myriam Consuelo; Quiroz, Damian Arnoldo; Pinilla, Analida Elizabeth

    2007-01-01

    The objective is to carry out a review of the national and international literature as of the XXth century in order to update the advances for the diagnosis of complex odd Entamoeba histolytic / Entamoeba dispar and that of intestinal and extra intestinal amoebiasis that may be of use to the scientific community. As well as to unify the diagnostic criteria of this parasitosis known as a public health problem, and as a consequence of that, optimize the quality of population care. Data source: there was a systematic search for the scientific literature Publisher in Spanish and English since 1960 until today, this selection started on the first semester of 2006 until 2007, in the development of the line on intestinal and extra-intestinal amoebiasis of the Medical School of the National University of Colombia. A retrospective search process was carried out, systematically reviewing the most relevant articles as well as the products of this research line. In deciding how to make this article, there was a continuous search in different data bases such as Medline, SciELO and other bases in the library of the National University of Colombia, as well as other classical books related to the subject. For that purpose the terms amoebiasis, odd Entamoeba histolytic, Entamoeba, diagnosis, epidemiology, dysentery, amoebic liver abscess, were used. Studies selection: titles and abstracts were reviewed to select the original publications and the most representative ones related to this article's subject. Data extraction: the articles were classified according to the subject, the chronology and the authors according to the scientific contribution to solve the problem. Synthesis of the data: in the fi rst instance, a chronological critical analysis was carried out to order and synthesize the progress made in the diagnosis until confirmation of the experts' agreements in the field of amoebiasis was obtained throughout the world. Conclusion: this article summarizes what has taken place

  13. LOS INDICIOS CONDUCTUALES EN EL PROCESO CIVIL

    Directory of Open Access Journals (Sweden)

    Mabel Londoño Jaramillo

    2006-12-01

    Full Text Available Las conductas procesales de las partes pueden estar dirigidas a la vulneración de normas de contenido ético o moral establecidas por el legislador; pero igualmente pueden traer como consecuencia la falta de colaboración en el proceso y, con ello, afectar la obtención de unos elementos probatorios necesarios para finalmente alcanzar la justa solución de la litis. En este sentido, el legislador colombiano ha diferenciado en los códigos procesales, conductas tendientes a contrarrestar el fraude procesal en desarrollo legal del principio de moralidad, que pueden ser objeto de un proceso disciplinario que se despache en la misma causa, y aquellas conductas, igualmente procesales, que deben valorarse en la sentencia por suministrar argumentos de prueba a través de la construcción de los respectivos indicios conductuales omisivos, oclusivos y mendaces. Es así como de una conducta procesal realizada por las partes, pueden obtenerse inferencias probatorias prescindiendo de toda clase de consideraciones éticas, y ello tipifica una conducta procesal desde el punto de vista probatorio.

  14. Intestinal anisakidosis (anisakiosis).

    Science.gov (United States)

    Takei, Hidehiro; Powell, Suzanne Z

    2007-10-01

    A case of intestinal anisakidosis in a 42-year-old man in Japan is presented. His chief complaint was an acute onset of severe abdominal pain. Approximately 12 hours before the onset of this symptom, he had eaten sliced raw mackerel ("sashimi"). Upper endoscopy was unremarkable. At exploratory laparotomy, an edematous, diffusely thickened segment of jejunum was observed, which was resected. The postoperative course was uneventful. The segment of small intestine showed a granular indurated area on the mucosal surface, and microscopically, a helminthic larva penetrating the intestinal wall, which was surrounded by a cuff of numerous neutrophils and eosinophils, as well as diffuse acute serositis. A cross section of the larva revealed the internal structures, pathognomonic of Anisakis simplex. Although anisakidosis is rare in the United States, with the increasing popularity of Japanese cuisine, the incidence is expected to increase, and pathologists should be familiar with this disease.

  15. Intestinal failure: a review

    Science.gov (United States)

    Allan, Philip; Lal, Simon

    2018-01-01

    Intestinal failure (IF) is the inability of the gut to absorb necessary water, macronutrients (carbohydrate, protein, and fat), micronutrients, and electrolytes sufficient to sustain life and requiring intravenous supplementation or replacement. Acute IF (types 1 and 2) is the initial phase of the illness and may last for weeks to a few months, and chronic IF (type 3) from months to years. The challenge of caring for patients with IF is not merely the management of the underlying condition leading to IF or the correct provision of appropriate nutrition or both but also the prevention of complications, whether thromboembolic phenomenon (for example, venous occlusion), central venous catheter-related bloodstream infection, IF-associated liver disease, or metabolic bone disease. This review looks at recent questions regarding chronic IF (type 3), its diagnosis and management, the role of the multidisciplinary team, and novel therapies, including hormonal treatment for short bowel syndrome but also surgical options for intestinal lengthening and intestinal transplant. PMID:29399329

  16. Small intestine diverticuli

    International Nuclear Information System (INIS)

    Pomakov, P.; Risov, A.

    1991-01-01

    The routine method of contrast matter passage applied to 850 patients with different gastrointestinal diseases proved inefficient to detect any small-intestinal diverticuli. The following modiffications of the method have been tested in order to improve the diagnostic possibilities of the X-ray: study at short intervals, assisted passage, enteroclysm, pharmacodynamic impact, retrograde filling of the ileum by irrigoscopy. Twelve diverticuli of the small-intestinal loops were identified: 5 Meckel's diverticuli, 2 solitary of which one of the therminal ileum, 2 double diverticuli and 1 multiple diverticulosis of the jejunum. The results show that the short interval X-ray examination of the small intestines is the method of choice for identifying local changes in them. The solitary diverticuli are not casuistic scarcity, its occurrence is about 0.5% at purposeful X-ray investigation. The assisted passage method is proposed as a method of choice for detection of the Meckel's diverticulum. 5 figs., 3 tabs. 18 refs

  17. Chronic intestinal pseudoobstruction syndrome

    International Nuclear Information System (INIS)

    Yeon, Kyung Mo; Seo, Jeong Kee; Lee, Yong Seok

    1992-01-01

    Chronic intestinal pseudoobstruction syndrome is a rare clinical condition in which impaired intestinal peristalsis causes recurrent symptoms of bowel obstruction in the absence of a mechanical occlusion. This syndrome may involve variable segments of small or large bowel, and may be associated with urinary bladder retention. This study included 6 children(3 boys and 3 girls) of chronic intestinal obstruction. Four were symptomatic at birth and two were of the ages of one month and one year. All had abdominal distension and deflection difficulty. Five had urinary bladder distension. Despite parenteral nutrition and surgical intervention(ileostomy or colostomy), bowel obstruction persisted and four patients expired from sepses within one year. All had gaseous distension of small and large bowel on abdominal films. In small bowel series, consistent findings were variable degree of dilatation, decreased peristalsis(prolonged transit time) and microcolon or microrectum. This disease entity must be differentiated from congenital megacolon, ileal atresia and megacystis syndrome

  18. Small Intestinal Infections.

    Science.gov (United States)

    Munot, Khushboo; Kotler, Donald P

    2016-06-01

    Small intestinal infections are extremely common worldwide. They may be bacterial, viral, or parasitic in etiology. Most are foodborne or waterborne, with specific etiologies differing by region and with diverse pathophysiologies. Very young, very old, and immune-deficient individuals are the most vulnerable to morbidity or mortality from small intestinal infections. There have been significant advances in diagnostic sophistication with the development and early application of molecular diagnostic assays, though these tests have not become mainstream. The lack of rapid diagnoses combined with the self-limited nature of small intestinal infections has hampered the development of specific and effective treatments other than oral rehydration. Antibiotics are not indicated in the absence of an etiologic diagnosis, and not at all in the case of some infections.

  19. The intestinal calcistat

    Directory of Open Access Journals (Sweden)

    M K Garg

    2013-01-01

    Full Text Available The main physiological function of vitamin D is maintenance of calcium homeostasis by its effect on calcium absorption, and bone health in association with parathyroid gland. Vitamin D deficiency (VDD is defined as serum 25-hydroxy vitamin D (25OHD levels <20 ng/ml. Do all subjects with VDD have clinical disease according to this definition? We hypothesize that there exist an intestinal calcistat, which controls the calcium absorption independent of PTH levels. It consists of calcium sensing receptor (CaSR on intestinal brush border, which senses calcium in intestinal cells and vitamin D system in intestinal cells. CaSR dampens the generation of active vitamin D metabolite in intestinal cells and decrease active transcellular calcium transport. It also facilitates passive paracellular diffusion of calcium in intestine. This local adaptation adjusts the fractional calcium absorption according the body requirement. Failure of local adaptation due to decreased calcium intake, decreased supply of 25OHD, mutation in CaSR or vitamin D system decreases systemic calcium levels and systemic adaptations comes into the play. Systemic adaptations consist of rise in PTH and increase in active vitamin D metabolites. These adaptations lead to bone resorption and maintenance of calcium homeostasis. Not all subjects with varying levels of VDD manifest with secondary hyperparathyroidism and decreased in bone mineral density. We suggest that rise in PTH is first indicator of VDD along with decrease in BMD depending on duration of VDD. Hence, subjects with any degree of VDD with normal PTH and BMD should not be labeled as vitamin D deficient. These subjects can be called subclinical VDD, and further studies are required to assess beneficial effect of vitamin D supplementation in this subset of population.

  20. Intestinal microbiota and ulcerative colitis.

    Science.gov (United States)

    Ohkusa, Toshifumi; Koido, Shigeo

    2015-11-01

    There is a close relationship between the human host and the intestinal microbiota, which is an assortment of microorganisms, protecting the intestine against colonization by exogenous pathogens. Moreover, the intestinal microbiota play a critical role in providing nutrition and the modulation of host immune homeostasis. Recent reports indicate that some strains of intestinal bacteria are responsible for intestinal ulceration and chronic inflammation in inflammatory bowel diseases (IBD) such as ulcerative colitis (UC) and Crohn's disease (CD). Understanding the interaction of the intestinal microbiota with pathogens and the human host might provide new strategies treating patients with IBD. This review focuses on the important role that the intestinal microbiota plays in maintaining innate immunity in the pathogenesis and etiology of UC and discusses new antibiotic therapies targeting the intestinal microbiota. Copyright © 2015 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

  1. Small intestine aspirate and culture

    Science.gov (United States)

    ... ency/article/003731.htm Small intestine aspirate and culture To use the sharing features on this page, please enable JavaScript. Small intestine aspirate and culture is a lab test to check for infection ...

  2. La subjetividad narrativa posmodema: procesos determinantes

    Directory of Open Access Journals (Sweden)

    Roca Sierra, Marcos

    2005-12-01

    Full Text Available Among the most relevant processes in the occurrence appearance of post modem subjectivity, there are five, in the judgement of the author, which determine the construction of the subject as a conscious act of narrative fictionalization, the latter being understood as a discoursed and reflexive practice. The processes are the following: The «schizophrenic» experience of reality as a result of the absence of meaning within the space-time parameters; the growing determination of the experience which causes what we could denominate as a tropological structure of reality; the crisis of the «metaphysics of presence» and its substitution for a necessary dialogical arrangement disposition in the construction of subjects; the progressive devaluation of symbolic categories in the construction of identity and the appearance of internally referential systems; and, finally, the centring and introspection of the subject in the interpretation of reality.Entre los procesos más relevantes en la aparición de la subjetividad posmoderna, cinco son, a juicio del autor, los que determinan la construcción del sujeto como un acto consciente de ficcionalización narrativa, entendida ésta como un proceso discursivo y reflejo. Los procesos son los siguientes: la vivencia «esquizofrénica» de la realidad como resultado de un vaciamiento del significado de los parámetros espacio-temporales; la creciente mediatización de la experiencia que origina lo que podríamos denominar una estructura tropológica de lo real; la crisis de la «metafísica de la presencia» y su sustitución por una necesaria disposición dialógica en la construcción de los sujetos; la devaluación progresiva de las categorías simbólicas en la construcción de la identidad y el surgimiento de sistemas internamente referenciales; y, por último, la centralidad e introspección del sujeto en la interpretación de la realidad.

  3. Stages of Small Intestine Cancer

    Science.gov (United States)

    ... all of an organ that contains cancer. The resection may include the small intestine and nearby organs (if the cancer has spread). The doctor may remove the section of the small intestine that contains cancer and perform an anastomosis (joining the cut ends of the intestine together). ...

  4. Intestinal inflammatory myofibroblastic tumour

    African Journals Online (AJOL)

    abdominal X-ray of patients 1, 3 and 4 demonstrated dilated small bowel loops with fluid levels in keeping with intestinal ... myxoid/vascular pattern characterised by a variable admixture of capillary-calibre blood vessels, .... in the present study had a past history of abdominal trauma or surgery. Ancillary histopathological ...

  5. Small intestine and microbiota.

    Science.gov (United States)

    Cotter, Paul D

    2011-03-01

    To highlight the recent studies which have enhanced our appreciation of the composition of the microbiota in the human small intestine and its relevance to the health of the host. In the past number of years, the composition of the microorganisms present in our small intestines has been the subject of greater scrutiny than ever before. These investigations have been possible as a consequence of the development and utilization of new molecular tools which have revolutionized the field of microbial ecology and have focused predominantly on the small intestinal microbiota associated with pediatric celiac disease, inflammatory bowel disease, irritable bowel syndrome and pouchitis. The impact of invasive procedures, such as small bowel transplant, ileostomy and ileal pouch anal anastomosis, on the ileal microbiota has also been investigated. The ever greater appreciation of the link between the small intestinal microbiota and the health status of the host has the potential to lead to the development of new strategies to alter this microbiota in a targeted way to prevent or treat specific disorders.

  6. Intestinal obstruction repair

    Science.gov (United States)

    ... Ileostomy and your diet Ileostomy - caring for your stoma Ileostomy - changing your pouch Ileostomy - discharge Ileostomy - what to ask your doctor Intestinal or bowel obstruction - discharge Low-fiber diet Surgical wound care - open Types of ileostomy When you have nausea ...

  7. adhesive intestinal obstruction

    African Journals Online (AJOL)

    2006-06-01

    Jun 1, 2006 ... obstruction. Brit. I. Surg. 1998; 85: 1071-1074. The acute abdomen: Intestinal obstruction. In: Primary surgery, Vol. 1. Edited by Maurice King et al. Oxford. Med. PubL, Oxford. 1990; 142-169. Fluids and electrolyte management. In: Essentials of pediatric surgery. Edited by Marc Rowe et al. Mosby,. St. Louis ...

  8. Intestinal Complications of IBD

    Science.gov (United States)

    ... localized pocket of pus caused by infection from bacteria. More common in Crohn’s than in colitis, an abscess may form in the intestinal wall—sometimes causing it to bulge out. Visible abscesses, such as those around the anus, look like boils and treatment often involves lancing. Symptoms of ...

  9. Intestinal failure in childhood

    African Journals Online (AJOL)

    Short bowel syndrome (SBS) was one of the first recognised conditions of protracted IF. With the increasing and successful use of long-term PN during the last three decades, several other causes of IF have emerged. Long-term PN and home-PN are the mainstay of therapy, independent of the nature of “Intestinal failure” ...

  10. La transferencia en el proceso educativo

    Directory of Open Access Journals (Sweden)

    Libia Elena Ramírez

    2011-01-01

    Full Text Available Este artículo pretende realizar una reflexión en torno a la transferencia como concepto nodal para pensar el proceso educativo. La autora utiliza como método el rastreo documental para conceptualizar la transferencia y hacer un análisis del rol docente desde las particularidades de dicho concepto y la teoría que lo soporta: la transferencia imaginaria y la simbólica, su relación con los ideales y con la labor pedagógica. La autora concluye que la labor docente debe hacerse desde la transferencia simbólica y que el docente debe estar muy atento a las inmersiones de su propia historia subjetiva en la relación con el estudiante.

  11. La transferencia en el proceso educativo

    Directory of Open Access Journals (Sweden)

    Libia Elena Ramírez Robledo

    2011-01-01

    Full Text Available Este artículo pretende realizar una reflexión en torno a la transferencia como concepto nodal para pensar el proceso educativo. La autora utiliza como método el rastreo documental para conceptualizar la transferencia y hacer un análisis del rol docente desde las particularidades de dicho concepto y la teoría que lo soporta: la transferencia imaginaria y la simbólica, su relación con  los ideales y con labor pedagógica. La autora concluye que la labor docente debe hacerse desde la transferencia simbólica y que el docente debe estar muy atento a las inmersiones de su propia historia subjetiva en la relación con el estudiante. © Revista Colombiana de Ciencias Sociales.

  12. fluidizado por proceso autotérmico

    Directory of Open Access Journals (Sweden)

    ZULAMITA ZAPATA BENABITHE

    2005-01-01

    Full Text Available El presente trabajo se basa en el estudio de la producción de carbón activado a partir de carbón mineral subbituminoso en un reactor de lecho fluidizado por proceso autotérmico. El carbón utilizado provino de la región de Amagá (Antioquia - Colombia y fue activado en dos reactores de lecho fluidizado de diferente diámetro interno, 10 cm y 22 cm. Los valores del área superficial específica y el volumen de poro de las muestras activadas fueron determinados a partir de las isotermas de N2 y CO2. Los resultados experimentales mostraron que los valores de áreas superficiales BET y DR y del Índice de Yodo se encontraron alrededor de 460 m2/g (SBET, 490 m2/g (SDR y 460 mg I2/g carbón.

  13. Mejora de los procesos cognitivos y discapacidad intelectual

    OpenAIRE

    Grau Rubio, Claudia

    2006-01-01

    Se describen las principales dificultades en los procesos cognitivos básicos (percepción, atención, memoria, procesos ejecutivos) y las actividades y programas para mejorarlos. Asimismo, se describen las dificultades de algunos síndromes que cursan discapacidad intelectual.

  14. Efecto de la aplicación de la vacuna antirrábica en canes vacunados durante la campaña de vacunación antirrábica masiva en Lima, Perú en 1993

    Directory of Open Access Journals (Sweden)

    Augusto Rodríguez

    2011-01-01

    Full Text Available En el presente trabajo se determinó la respuesta inmune posterior a las campañas de vacunación antirrábica masiva realizadas en 19 distritos de la ciudad de Lima. El método utilizado fue la titulación de anticuerpos antirrábicos mediante la prueba de seroneutralización en ratón, técnica que fue aplicado a un muestreo significativo de sueros sanguíneos de la población de canes vacunados. Se tomaron al azar 54 muestras de canes mordedores que ingresaron al Centro Antirrábico de Lima para ser observados clínicamente por un periodo de 10 días. De las 54 muestras de suero que se sometieron a la prueba, 28 (52% fueron positivos (títulos de 0,5-8,39 UI/ml, mientras que las 26 (48% muestras restantes dieron títulos inferiores a 0,5 UI/ml y otros fueron negativos a la prueba. El grupo etáreo de mayor muestreo correspondió a la población de canes de más riesgo (1-3 años de edad. En este grupo etáreo, 14 canes (26% presentaron sueros con títulos de protección, mientras que en 18 canes (33% la prueba fue negativa. En lo referente al sexo, el grupo de canes machos (considerados de mayor riesgo presentaron mayor número de individuos (44 canes respecto al grupo de hembras (10 canes y solo en 24 canes machos (45% dieron títulos de protección antirrábica. En conclusión, podemos decir que el 52% de canes vacunados durante las anteriores campañas de vacunación antirrábica masiva en la ciudad de Lima, en 1993, tuvieron títulos de anticuerpos protectores contra el virus de la rabia.

  15. Colgajo libre osteoseptocutáneo de peroné en la reconstrucción primaria de la radionecrosis masiva mandibular Fibular osteoseptocutaneous free flap in the primary reconstruction after massive radionecrosis of the mandible

    Directory of Open Access Journals (Sweden)

    P. Infante Cossío

    2004-06-01

    Full Text Available Resumen: Una de las complicaciones más serias del uso de la radioterapia en el tratamiento del carcinoma epidermoide de la cavidad oral, es la osteorradionecrosis. En este trabajo, presentamos cuatro pacientes afectos de osteorradionecrosis masiva de la mandíbula que habían fracasado inicialmente con medidas conservadoras y que fueron tratados con resección radical y reconstrucción primaria con un colgajo libre osteoseptocutáneo de peroné. El defecto mandibular tras la resección ósea midió una media de 10 cm e incluyó mucosa intraoral, piel o ambos. En dos casos de reconstrucción, se empleó el colgajo libre de peroné con doble paleta para reconstruir defectos extensos intra y extraorales. Se realizaron osteotomías en el peroné vascularizado en todos los casos para recrear el contorno mandibular. Todos los colgajos sobrevivieron completamente. Tres pacientes curaron primariamente con buenos resultados estéticos y funcionales. Una paciente falleció en el primer mes tras la operación por una pancreatitis aguda y fallo renal. En un paciente se han insertado implantes osteointegrados. En nuestra experiencia, el colgajo libre osteoseptocutáneo de peroné puede ser una opción ideal para la reconstrucción en un solo tiempo de defectos complejos mandibulares compuestos en pacientes afectos de osteorradionecrosis masiva.Abstract: Osteoradionecrosis is one of the most serious complications after radiation therapy of squamous carcinoma of the oral cavity. In this article, we report four cases of massive osteoradionecrosis of the mandible, all of whom had failed initial conservative management and treated with radical resection and primary reconstructed with fibular osteoseptocutaneous free flap. Mandible defects after radical resection were around 10 cm long and included intraoral mucosa, skin or both. A doubled-paddle peroneal tissue transfer was used in two cases for reconstruction of an extensive extra- or intraoral defects. The

  16. Implementación y evaluación de una estrategia combinada de educación en salud y quimioterapia masiva para el control de las geohelmintiasis, en una zona rural de Colombia

    Directory of Open Access Journals (Sweden)

    Julián A. Fernández-Niño

    2015-08-01

    Full Text Available Introducción: Las geohelmintiasis son infecciones prevalentes en los países en vía de desarrollo, que afectan principalmente a la población escolar. Las estrategias de control que combinan quimioterapia masiva con educación en salud, pueden producir reducciones significativas de estas infecciones, sostenibles en el tiempo. En este estudio se implementó y evaluó, una intervención integral basada en una estrategia lúdica de educación en salud, más quimioterapia masiva en una zona rural de Colombia. Metodología: Diseño cuasi-experimental, realizado en La Virgen, Cundinamarca (Colombia. Toda la población escolar fue sometida a la estrategia educativa en salud, acompañada de tratamiento semestral con albendazol, entre finales del 2010 y mediados del 2013. La muestra analítica fue constituida por 119 niños (mediana= 11; Rango Intercuartílico = 8-13 años. Se evaluaron los cambios anuales en la presencia de geohelmintos usando pruebas no paramétricas para muestras relacionadas y modelos de regresión logística de efectos fijos. Resultados: En la medición basal, las prevalencias de los geohelmintos fueron: 22,28% (IC 95% 16,36%-28,20% para Ascaris lumbricoides; 37,31% (IC 95% 30,42%-44,19% para Trichuris trichiura y 13,47% (IC 95% 8,61%-18,33% para Uncinaria sp. Para la medición final, estas prevalencias cayeron significativamente a 5,30% (IC 95% 1,68%-8,91% para A. lumbricoides; 16,55% (IC 95% 10,56%-22,55% para T. trichiura y 4,64% (IC95% 1,42%-8,03% para Uncinaria sp. Conclusión: El presente estudio, pese a que no constituye una evaluación real de impacto, provee una experiencia aparentemente exitosa de implementación de una estrategia integral para el control de las geohelmintiasis, que podría servir como modelo para otras intervenciones en áreas rurales del país.

  17. Small intestinal transplantation.

    LENUS (Irish Health Repository)

    Quigley, E M

    2012-02-03

    The past few years have witnessed a considerable shift in the clinical status of intestinal transplantation. A great deal of experience has been gained at the most active centers, and results comparable with those reported at a similar stage in the development of other solid-organ graft programs are now being achieved by these highly proficient transplant teams. Rejection and its inevitable associate, sepsis, remain ubiquitous, and new immunosuppressant regimes are urgently needed; some may already be on the near horizon. The recent success of isolated intestinal grafts, together with the mortality and morbidity attendant upon the development of advanced liver disease related to total parenteral nutrition, has prompted the bold proposal that patients at risk for this complication should be identified and should receive isolated small bowel grafts before the onset of end-stage hepatic failure. The very fact that such a suggestion has begun to emerge reflects real progress in this challenging field.

  18. EL PROCESO DE ORDENAMIENTO AMBIENTAL EN CUBA

    Directory of Open Access Journals (Sweden)

    Obllurys Cárdenas López

    2014-01-01

    Full Text Available La necesaria interacción entre el ordenamiento territorial y ordenamiento ambiental fue promulgada en la Ley 81 y en las Estrategias Ambientales Nacionales (EAN desde 1997, en Cuba. Varias situaciones frenaron su cumplimentación, la falta de procedimientos metodológicos que guiaran el proceso, fue una de ellas por lo que la EAN de 2011-2015 y los Lineamientos del PCC lo ratifican como objetivo. En el abordaje de este problema y en la inclusión de los resultados de los estudios de peligro, vulnerabilidad y riesgo y de los escenarios de cambio climático radica la actualidad de la presente investigación. Teniendo como hipótesis que: el empleo de procedimientos metodológicos integradores y participativos facilitará la elaboración de modelos de ordenamiento ambiental (MOA que aporten regulaciones, lineamientos y normas ambientales al proceso de ordenamiento territorial; se persigue como objetivo principal: proponer los procedimientos metodológicos para la elaboración de los MOA y realizar su validación a nivel nacional y municipal. Son empleados métodos teóricos y empíricos combinados en la elaboración de los procedimientos y en su validación a diferentes escalas. Se obtienen como resultado los procedimientos metodológicos, con cinco fases de trabajo y su validación con la elaboración del MOA para el territorio emergido de Cuba, para los sectores agrícola y pecuario y del MOA para el municipio de Yagüajay, para los sectores agrícola, pecuario, forestal, hídrico, turismo y conservación. Se concluyó en la pertinencia de utilizar los procedimientos propuestos para la elaboración de los MOA, teniendo como base el enfoque participativo y a las unidades de paisaje, como unidad de análisis.

  19. Trayectorias industriales metropolitanas: nuevos procesos, nuevos contrastes

    Directory of Open Access Journals (Sweden)

    Inmaculada Caravaca

    2003-08-01

    Full Text Available La realidad industrial y urbana ha estado sometida a un fuerte proceso de reestructuración durante las últimas décadas. En la primera mitad de la década de los ‘80, conceptos como los de desindustrialización, o postindustrialización fueron asociados a los de desurbanización o contraurbanización. Sólo unos años más tarde el discurso empezó a ser radicalmente distinto al confirmarse la permanencia de fuertes externalidades positivas urbano-metropolitanas, y volvieron a considerarse tales ámbitos como ganadores. Las páginas que siguen intentarán sintetizar algunas de esas transformaciones que conocen las empresas y los espacios industriales metropolitanos en los últimos añosUrban and industrial reality has undergone a strong process of restructuring during the last decades. In the first half of the 80’s, concepts like de-industrialization or post-industrialization were associated with those of de-urbanization or counter-urbanization. Only a few years later the argument became to be radically different after the confirmation of strong positive urban-metropolitan externalities, and urban areas turned back to be considered as winning spaces. The following pages will try to summarize some of these transformations, which metropolitan firms and industrial areas have experimented in the last years

  20. Small intestinal cytochromes P450.

    Science.gov (United States)

    Kaminsky, L S; Fasco, M J

    1991-01-01

    Small intestinal cytochromes P450 (P450) provide the principal, initial source of biotransformation of ingested xenobiotics. The consequences of such biotransformation are detoxification by facilitating excretion, or toxification by bioactivation. P450s occur at highest concentrations in the duodenum, near the pylorus, and at decreasing concentrations distally--being lowest in the ileum. Highest concentrations occur from midvillus to villous tip, with little or none occurring in the crypts of Lieberkuehn. Microsomal P4503A, 2C8-10, and 2D6 forms have been identified in human small intestine, and P450s 2B1, possibly 2B2, 2A1, and 3A1/2 were located in endoplasmic reticulum of rodent small intestine, while P4502B4 has been purified to electrophoretic homogeneity from rabbit intestine. Some evidence indicates a differential distribution of P450 forms along the length of the small intestine and even along the villus. Rat intestinal P450s are inducible by xenobiotics--with phenobarbital (PB) inducing P4502B1, 3-methylcholanthrene (3-MC) inducing P4501A1, and dexamethasone inducing two forms of P4503A. Induction is most effectively achieved by oral administration of the agents, and is rapid--aryl hydrocarbon hydroxylase (AHH) was increased within 1 h of administration of, for example, 3-MC. AHH, 7-ethoxycoumarin O-deethylase (ECOD), and 7-ethoxyresorufin O-deethylase (EROD) have been used most frequently as substrates to characterize intestinal P450s. Dietary factors affect intestinal P450s markedly--iron restriction rapidly decreased intestinal P450 to beneath detectable values; selenium deficiency acted similarly but was less effective; Brussels sprouts increased intestinal AHH activity 9.8-fold, ECOD activity 3.2-fold, and P450 1.9-fold; fried meat and dietary fat significantly increased intestinal EROD activity; a vitamin A-deficient diet increased, and a vitamin A-rich diet decreased intestinal P450 activities; and excess cholesterol in the diet increased intestinal

  1. Lipo sarcoma in small intestine

    International Nuclear Information System (INIS)

    Rodriguez Iglesias, J.; Pineyro Gutierrez, A.; Taroco Medeiros, L.; Fein Kolodny, C.; Navarrete Pedocchi, H.

    1987-01-01

    A case is presented by primitive liposarcoma in small intestine , an extensive bibliographical review foreigner and national in this case. It detach the exceptional of the intestinal topography of the liposarcomas; and making stress in the relative value of the computerized tomography and ultrasonography in the diagnose of the small intestine tumors . As well as in the sarcomas of another topography, chemo and radiotherapy associated to the exeresis surgery, it can be of benefit [es

  2. Procesos compartidos: Los constructores de eventos

    Directory of Open Access Journals (Sweden)

    María Auxiliadora Gálvez Pérez

    2015-05-01

    Full Text Available ResumenLos procesos creativos comparados en danza y arquitectura constituyen un panorama capaz de alumbrar una realidad con connotaciones perceptivas distintas. Se trata de una realidad donde lo relevante es la inmersión en los fenómenos espacio temporales, la experiencia del contacto del espacio de nuestro cuerpo con la esencia espacial que está fuera del límite de nuestra piel. Desde el punto de vista arquitectónico la danza aparecería como una disciplina clave, como un laboratorio donde indagar con total libertad en los conceptos relativos al sistema cuerpo y espacio y por consiguiente en las herramientas necesarias para trabajar con ellos. Uno de los ejemplos más signifi cativos de este laboratorio que se consolida en la intersección de los procesos coreográficos y arquitectónicos será la colaboración entre Lawrence Halprin, arquitecto paisajista, y Anna Halprin,coreógrafa. A través de la experiencia directa del cuerpo en el espacio desarrollarán notaciones y ciclos creativos capaces de trabajar con el material que nos proporciona esta percepción expandida. La revisión de estos ciclos creativos desarrollados principalmente en los años sesenta esespecialmente pertinente en este momento cuando desde la fi losofía, diversas ramas- cuyas raíces son relativas a la fenomenología- se interesan precisamente por la danza y la arquitectura como territorios clave. Parece el momento oportuno para expandir las herramientas arquitectónicas que hasta al momento se han puesto en marcha de forma general desde los intereses fenomenológicos. AbstractThe comparison between the creative processes in dance and architecture constitute a panorama, which is able to fi gure out reality with different and intense perceptive connotations. It is about a reality where the important thing is the immersion into the spatial-temporal phenomena, the contact of the space of our body and the spatial essence that is outside our skin limits. Under an

  3. Hereditary intestinal polyposis syndromes.

    Science.gov (United States)

    Dean, P A

    1996-01-01

    Colorectal cancer is one of the most common cancers in the world, with overall mortality exceeding 40% even with treatment. Effective efforts for screening and prevention are most likely to succeed in patient groups identified as high risk for colorectal cancer, most notably the hereditary intestinal polyposis syndromes. In these syndromes, benign polyps develop throughout the intestinal tract prior to the development of colorectal cancer, marking the patient and associated family for precancer diagnosis followed by either close surveillance or preventive treatment. This review article was undertaken to discuss the most recent developments in the knowledge of hereditary intestinal polyposis syndromes, emphasizing the clinical approach to diagnosis and treatment relative to preventing the development of cancer. The most common of the hereditary polyposis syndromes is familial adenomatous polyposis (FAP), which is characterized by the development of hundreds to thousands of adenomatous polyps in the colon followed at an early age by colorectal cancer. Colorectal cancer can be prevented in this autosomal dominant condition by prophylactic colectomy, though a risk for other tumors, including periampullary cancers, remains throughout life. Variant of FAP associated with fewer and smaller polyps (hereditary flat adenoma syndrome), or even CNS tumors (Turcot's syndrome) also carry this high risk of colorectal cancer. Hereditary hamartomatous polyposis syndromes such as juvenile polyposis and Peutz-Jeghers syndrome (also autosomal dominant) are characterized by less frequent polyps. Though these are generally benign polyps, they are also associated with a significant risk of colorectal and other cancers. Other polyposis syndromes, including neurofibromatosis and Cowden's disease, do not carry this increased risk of colorectal cancer, and therefore affect different treatment strategies. Analysis of genetic factors responsible for these and other hereditary syndromes with

  4. Intestinal parasites : associations with intestinal and systemic inflammation

    NARCIS (Netherlands)

    Zavala, Gerardo A; García, Olga P; Camacho, Mariela; Ronquillo, Dolores; Campos-Ponce, Maiza; Doak, Colleen; Polman, Katja; Rosado, Jorge L

    2018-01-01

    AIMS: Evaluate associations between intestinal parasitic infection with intestinal and systemic inflammatory markers in school-aged children with high rates of obesity. METHODS AND RESULTS: Plasma concentrations of CRP, leptin, TNF-α, IL-6 and IL-10 were measured as systemic inflammation markers and

  5. PROCESO DE FABRICACIÓN DE LAS LLANTAS DE CAUCHO

    OpenAIRE

    Carrión Nin, José Luis; Universidad Nacional Mayor de San Marcos

    2014-01-01

    En esta síntesis, desarrollo una breve explicación acerca de la preparación, construcción y los métodos de manufactura del proceso de fabricación de las llantas de caucho. Si bien es breve, esta información brindará una idea global y simple del proceso de fabricación que de por si es interesante. Los rasgos del proceso se muestran en un diagrama. La fase inicial del proceso es la preparación del caucho, este se inicia con la mezcla de los componentes en conformidad con una fórmula científic...

  6. Modelo de Proceso de Conceptualización de Requisitos

    Directory of Open Access Journals (Sweden)

    Alejandro Hossian

    2013-06-01

    Full Text Available El proceso de captura de requisitos constituye un proceso con connotaciones sociales relacionadas con diferentes personas (stakeholders, una circunstancia que hace que se presenten ciertos problemas cuando se lleva adelante la conceptualización de requisitos. En este trabajo se propone un Proceso de Conceptualización de Requisitos que se estructura en dos fases: (a Análisis Orientado a al Problema: cuyo objetivo es comprender el problema dado por el usuario en el dominio en el que este se lleva a cabo, y (b Análisis de Orientado al Producto: cuyo objetivo es obtener las funcionalidades que el usuario espera del producto de software a desarrollar, teniendo en cuenta la relación de estas con la realidad expresada por el usuario en su discurso. Se proponen seis técnicas que articulan cada una de las tareas que componen las fases de proceso propuesto.

  7. Adaptación positiva en el proceso de envejecimiento

    OpenAIRE

    Miguel Negredo, Adelia de

    2001-01-01

    La autora plantea que la última etapa del ciclo vital de los seres humanos no debe interpretarse como involutiva. Posteriormente expone una serie de mitos y modelos que explican el proceso de envejecimiento. Finalmente se planteo el concepto de envejecimiento satisfactorio y concluye con algunas propuestas de actuación personal, social y profesional que faciliten el proceso de adaptación al envejecimiento.

  8. Cytokines and intestinal inflammation.

    Science.gov (United States)

    Bamias, Giorgos; Cominelli, Fabio

    2016-11-01

    Cytokines of the intestinal microenvironment largely dictate immunological responses after mucosal insults and the dominance of homeostatic or proinflammatory pathways. This review presents important recent studies on the role of specific cytokines in the pathogenesis of intestinal inflammation. The particular mucosal effects of cytokines depend on their inherent properties but also the cellular origin, type of stimulatory antigens, intermolecular interactions, and the particular immunological milieu. Novel cytokines of the interleukin-1 (IL-1) family, including IL-33 and IL-36, have dominant roles in mucosal immunity, whereas more established ones such as IL-18 are constantly enriched with unique properties. Th17 cells are important mucosal constituents, although their profound plasticity, makes the specific set of cytokines they secrete more important than their mere numbers. Finally, various cytokines, such as tumor necrosis factor-α, IL-6, tumor necrosis factor-like cytokine 1A, and death receptor, 3 demonstrate dichotomous roles with mucosa-protective function in acute injury but proinflammatory effects during chronic inflammation. The role of cytokines in mucosal health and disease is increasingly revealed. Such information not only will advance our understanding of the pathogenesis of gut inflammation, but also set the background for development of reliable diagnostic and prognostic biomarkers and cytokine-specific therapies.

  9. Hippo signalling directs intestinal fate

    DEFF Research Database (Denmark)

    le Bouteiller, Marie Catherine M; Jensen, Kim Bak

    2015-01-01

    Hippo signalling has been associated with many important tissue functions including the regulation of organ size. In the intestinal epithelium differing functions have been proposed for the effectors of Hippo signalling, YAP and TAZ1. These are now shown to have a dual role in the intestinal epit...

  10. MDCT in blunt intestinal trauma

    Energy Technology Data Exchange (ETDEWEB)

    Romano, Stefania [Department of Diagnostic Imaging, ' A.Cardarelli' Hospital, 80131 Naples (Italy)]. E-mail: stefromano@libero.it; Scaglione, Mariano [Department of Diagnostic Imaging, ' A.Cardarelli' Hospital, 80131 Naples (Italy); Tortora, Giovanni [Department of Diagnostic Imaging, ' A.Cardarelli' Hospital, 80131 Naples (Italy); Martino, Antonio [Trauma Center, ' A.Cardarelli' Hospital, 80131 Naples (Italy); Di Pietto, Francesco [Department of Diagnostic Imaging, ' A.Cardarelli' Hospital, 80131 Naples (Italy); Romano, Luigia [Department of Diagnostic Imaging, ' A.Cardarelli' Hospital, 80131 Naples (Italy); Grassi, Roberto [Department ' Magrassi-Lanzara' , Section of Radiology, Second University of Naples, 80138 Naples (Italy)

    2006-09-15

    Injuries to the small and large intestine from blunt trauma represent a defined clinical entity, often not easy to correctly diagnose in emergency but extremely important for the therapeutic assessment of patients. This article summarizes the MDCT spectrum of findings in intestinal blunt lesions, from functional disorders to hemorrhage and perforation.

  11. MDCT in blunt intestinal trauma

    International Nuclear Information System (INIS)

    Romano, Stefania; Scaglione, Mariano; Tortora, Giovanni; Martino, Antonio; Di Pietto, Francesco; Romano, Luigia; Grassi, Roberto

    2006-01-01

    Injuries to the small and large intestine from blunt trauma represent a defined clinical entity, often not easy to correctly diagnose in emergency but extremely important for the therapeutic assessment of patients. This article summarizes the MDCT spectrum of findings in intestinal blunt lesions, from functional disorders to hemorrhage and perforation

  12. Análisis de la seguridad integral en los procesos electorales: Caso proceso electoral 2017 de Ecuador

    Directory of Open Access Journals (Sweden)

    Jeffry Badí Quinteros Basantes

    2018-01-01

    Full Text Available En este documento se muestra un análisis de la seguridad integral del proceso electoral 2017 realizado en la República del Ecuador. Este estudio incluye los enfoques de seguridad que se llevaron a cabo en este proceso: seguridad de la información, seguridad física segmentada en seguridad a procesos electorales y seguridad de la ciudadanía. Se mostrarán los elementos en cada uno de estos ámbitos, su ejecución, los elementos principales y las instituciones de apoyo que colaboraron en la seguridad para poder mantener la paz e institucionalidad del país en el proceso electoral 2017, con el fin de que el Consejo Nacional Electoral pudiera cumplir con el mandato constitucional y respetar la voluntad de los ciudadanos

  13. Modulation of Intestinal Microbiome Prevents Intestinal Ischemic Injury

    Directory of Open Access Journals (Sweden)

    Alessandra Bertacco

    2017-12-01

    Full Text Available Background: Butyrate protects against ischemic injury to the small intestine by reducing inflammation and maintaining the structure of the intestinal barrier, but is expensive, short-lived, and cannot be administered easily due to its odor. Lactate, both economical and more palatable, can be converted into butyrate by the intestinal microbiome. This study aimed to assess in a rat model whether lactate perfusion can also protect against intestinal ischemia.Materials and Methods: Rat intestinal segments were loaded in an in vitro bowel perfusion device, and water absorption or secretion was assessed based on fluorescence of FITC-inulin, a fluorescent marker bound to a biologically inert sugar. Change in FITC concentration was used as a measure of ischemic injury, given the tendency of ischemic cells to retain water. Hematoxylin and eosin-stained sections at light level microscopy were examined to evaluate intestinal epithelium morphology. Comparisons between the data sets were paired Student t-tests or ANOVA with p < 0.05 performed on GraphPad.Results: Lactate administration resulted in a protective effect against intestinal ischemia of similar magnitude to that observed with butyrate. Both exhibited approximately 1.5 times the secretion exhibited by control sections (p = 0.03. Perfusion with lactate and methoxyacetate, a specific inhibitor of lactate-butyrate conversion, abolished this effect (p = 0.09. Antibiotic treatment also eliminated this effect, rendering lactate-perfused sections similar to control sections (p = 0.72. Perfusion with butyrate and methoxyacetate did not eliminate the observed increased secretion, which indicates that ischemic protection was mediated by microbial conversion of lactate to butyrate (p = 0.71.Conclusions: Lactate's protective effect against intestinal ischemia due to microbial conversion to butyrate suggests possible applications in the transplant setting for reducing ischemic injury and ameliorating intestinal

  14. Viabilidad de huevos y modelo de jaula para la cría artificial masiva de Anastrepha fraterculus (Diptera: Tephritidae Viability of eggs and screen cage model for mass artificial rearing of Anastrepha fraterculus (Diptera: Tephritidae

    Directory of Open Access Journals (Sweden)

    Juliana García

    2011-12-01

    Full Text Available El objetivo del presente trabajo fue determinar la viabilidad de huevos y el modelo de jaula apropiada para la cría artificial masiva de Anastrepha fraterculus (Wiedemann. Los resultados muestran que el periodo de máxima oviposición ocurre durante los primeros 10 días en jaulas modelo Mediana, lo cual permite obtener el volumen de huevos necesario para alimentar el pie de cría de A. fraterculus en una cría masiva. Considerando que se encontró relación positiva entre el volumen de huevos ovipositados y el porcentaje de eclosión de huevos, en un periodo de 21 días de colecta, este periodo coincide además con los valores de eclosión más altos. Entre los modelos de jaulas evaluadas: Mediana, Grande y Mission; el modelo Mediana mostró los mejores resultados al evaluar el número de ía con un valor promedio de 11,4. La jaula que mostró menores resultados fue el modelo Mission, con un valor promedio de 4,6 huevos/hembra/día. Las jaulas grandes mostraron valores menores a las jaulas Medianas, pero las diferencias fueron no significativas. Los buenos valores registrados en las jaulas Medianas posiblemente se deban a la estructura de la jaula, que presentó la cara interna dividida en muchos compartimientos, lo cual mejora la distribución de las moscas adultas y previene la mortalidad temprana por hacinamiento en la base o en el techo de la jaula.The aim of this study was to determine the viability of eggs and cage model suitable for artificial mass rearing of Anastrepha fraterculus (Wiedemann. The results show that the period of maximum oviposition occurs during the first 10 days in Medium cages which allows to obtain the necessary volume of eggs to feed the foot of rearing of A. fraterculus in a mass rearing. Considering that a positive relationship was found between the volume of eggs oviposited and the hatchability percentage in a period of 21 days of collection, this period coincides with the highest values of hatching. Among the

  15. La sentencia Schrems del Tribunal de Justicia de la Unión Europea: un paso firme en la defensa del derecho a la privacidad en el contexto de la vigilancia masiva transnacional

    Directory of Open Access Journals (Sweden)

    María Isabel Puerto

    2017-12-01

    Full Text Available Las filtraciones de Edward Snowden demostraron al mundo la existencia de programas de vigilancia masiva implementados por Estados Unidos y otros aliados. Tales programas, supuestamente, estaban dirigidos a la recopilación de información para la prevención y represión del terrorismo, pero en la práctica implicaron violaciones inaceptables al derecho fundamental a la privacidad no solo de ciudadanos estadounidenses, sino de otras nacionalidades. Diversos actores de las Naciones Unidas y otras organizaciones internacionales han reaccionado mediante la elaboración de informes que manifiestan una elevada preocupación por el fenómeno de la vigilancia transnacional de masas y que pretenden ensalzar el discurso de los derechos humanos como límite contra las injerencias en la privacidad. En este contexto, el Tribunal de Justicia de la Unión Europea pronunció en el año 2015 la sentencia Schrems que invalidó una decisión de la Comisión Europea sobre el Acuerdo de Puerto Seguro que regulaba la transferencia de datos personales desde la Unión Europea a Estados Unidos. Este trabajo analiza críticamente dicha sentencia, porque ofrece interesantes aportaciones para la protección de los derechos a la privacidad y la protección de los datos personales, habiéndose convertido en un leading case de referencia obligada para la resolución de casos similares.

  16. Algoritmo inteligente para evaluar el impacto de la introducción masiva de cocinas de inducción; Intelligent algorithm for evaluating the impact of the introduction of mass induction

    Directory of Open Access Journals (Sweden)

    Jorge Enrique Carrión González

    2015-09-01

    Full Text Available El Ministerio de Electricidad y Energía Renovable de Ecuador (MEER está implementando el plan nacional de coccióneficiente, en el país y en la región Sur. El plan se basa en reemplazar las cocinas que usan gas licuado de petróleo (GLPpor cocinas eléctricas de inducción, estos cambios representan un aumento considerable en la demanda eléctrica delsector residencial. Los estudios de los sistemas eléctricos de distribución realizados permiten evaluar el comportamientoactual de las redes eléctricas y analizar futuros escenarios para poder determinar las mejoras de carácter técnico yorganizativo que deben introducirse. Seelaboró un algoritmo genético especializado para evaluar el efecto querepresenta en los transformadores de distribución la introducción masiva de las cocinas de inducción, con vistas aresolver el problema de un crecimiento brusco de la demanda de energía, minimizando los costos de inversión en nuevosequipos de transformación.The Ministry of Electricity and Renewable Energy of Ecuador (MEER is implement in the national plan for efficient cooking in thesouthern region and the country. The planes based on replacing kitchens using liquefied petroleum gas (LPG for induction cookers,representing an increase in electricity demanding the residential sector. Studies of electrical distribution systems made it possible toassess the current behavior of electrical networks and analyze future scenarios to determinism provident in technical and organizationalmeasures to be introduced. A genetic algorithm to evaluate the effect on distribution transformer soft he massive introduction ofinduction cookers, with view to resolving the problem of sharp growthin demand for energy while minimizing the costs of investment innew equipment was developed.

  17. Megacystis microcolon intestinal hypoperistalsis syndrome

    Science.gov (United States)

    Hiradfar, Mehran; Shojaeian, Reza; Dehghanian, Paria; Hajian, Sara

    2013-01-01

    Megacystis microcolon intestinal hypoperistalsis syndrome (MMIHS) is a multisystemic disorder in which impaired intestinal motor activity causes recurrent symptoms of intestinal obstruction in the absence of mechanical occlusion, associated with bladder distention without distal obstruction of the urinary tract. MMIHS and prune belly syndrome may overlap in most of the clinical features and discrimination of these two entities is important because the prognosis, management and consulting with parents are completely different. MMIHS outcome is very poor and in this article we present two neonates with MMIHS that both died in a few days. PMID:23729700

  18. INFANTS’ INTESTINAL COLICS. MODERN DATA

    Directory of Open Access Journals (Sweden)

    N.I. Ursova

    2011-01-01

    Full Text Available The article analyzes modern data on infants’ intestinal colics. Peculiarities of nutrition, intestinal microbiocenose in healthy infants, methods of colcs’ correction are discussed. Author describes the principles of probiotics choice based on their clinical effectiveness in infants. Milk formula «Nan Comfort» can be useful in prophylaxis and treatment of functional disorders of gastrointestinal tract in children.Key words: infants, gastrointestinal tract, anatomy, physiology, intestinal colics, nutrition, probiotics.(Voprosy sovremennoi pediatrii — Current Pediatrics. 2011; 10 (2: 125–131

  19. El proceso reproductivo: Algunas consideraciones sobre el maternaje

    Directory of Open Access Journals (Sweden)

    Ignacio González Labrador

    2001-10-01

    Full Text Available Se realizaron una serie de consideraciones generales sobre el proceso reproductivo, y como una consecuencia de él se consolida un proceso llamado maternaje, conceptualizándose según criterio del autor, cómo puede influir en la vida sexual de la mujer. Se conceptualiza según las letras que componen la palabra que denomina dicho procesoA series of general considerations on the reproductive process as a result of which the so-called motherhood process is strengthened were presented in this paper. The author conceptualizes the influence of this process on the woman’s sexual life. The conceptualization is based on the letters of the word defining such a process

  20. Disorders of the Small Intestine

    Science.gov (United States)

    ... that move down the intestine in a peristaltic fashion (Phase III). Phase III represents a continuation of ... Activities, Legislative & Regulatory Research Leadership Contact us News Industry Treatment News Medical News Legislative & Regulatory News Press ...

  1. Defence Mechanisms during Intestinal Infection

    Directory of Open Access Journals (Sweden)

    André Buret

    1991-01-01

    Full Text Available This review examines and compares host defence mechanisms during intestinal infection with three types of organisms: a virus, a bacterium and a nematode parasite (ie, transmissible gastroenteritis virus [TGEV], Helicobacter jejuni and Trichinella spiralis. Diarrhea is commonly associated with all of these infections. It appears that T spiralis initiates the most elaborate defence system of the three organisms, involving full range humoral and cellular immunity, as well as mucus hypersecretion, epithelial alterations, altered gut motility and parasite impairment (morphological and physiological. In contrast, intestinal defence against H jejuni and TGEV involves fewer components. The latter seems to initiate the most rudimentary host response. Despite such differences, these mechanisms exhibit many similarities, thus further illustrating the relatively limited repertoire of defence systems that the intestine can mount. The mediators translating the insult of any intestinal pathogen into a common response deserve further investigation.

  2. INTESTINAL INTUSSUSCEPTION DUE TO CONCURRENT ...

    African Journals Online (AJOL)

    Administrator

    Hymenolepis nana and Dentostomella ... worms (H. nana and D. translucida) were observed in the lumen of the intestine with severe cellular infiltration .... helminthosis and Balantidosis in Red monkey (Erythrocebus patas) in Ibadan Nigeria Nigerian ...

  3. Incidencias del proceso histórico en el proceso educativo argentino

    Directory of Open Access Journals (Sweden)

    William Roberto Daros

    2014-01-01

    Full Text Available El artículo aporta una relación panorámica y conceptual sobre la educación argentina. En él se presentan los inicios de las propuestas educativas, la presencia de la visión positivista, la legislación sobre la educación en el siglo XIX, la presencia estudiantil universitaria, la incidencia de la dictadura militar, un proyecto posterior de país que tendía al desarrollo industrial y la correspondiente legislación federal de educación. La metodología empleada en este artículo consiste en recurrir a datos históricos –sin hacer una historia de la educación– del proceso educativo formal en Argentina, a fin de sostener la hipótesis de que este se ha constituido sobre una doble vertiente cuya sombra se extiende hasta el presente. Para lograr este objetivo y corroborar esta hipótesis se ponen de manifiesto: a cómo las situaciones históricas, por medio de sus pensadores y políticos y de su legislación más representativa, b inciden en el presente del proceso educativo argentino, referido especialmente al nivel primario y secundario, c al generar una forma de ser sociocultural peculiar. No se pretende, pues, hallar una novedad histórica sino una forma de lectura diferente, para lograr tener conciencia acerca de cómo: a las decisiones políticas y culturales, b tomadas en el pasado c no han sido inofensivas, d lo que es una lección para el presente. Estas referencias históricas hacen visibles las pugnas que, dentro de la misma sociedad argentina, los bandos protagonistas iban generando. Estos fueron primeramente pro religiosos o pro laicos; y luego estos bandos se convirtieron en el federal y el unitario, no exento de corrupción, que perduran hasta el presente, en una no siempre fácil convivencia nacional.

  4. Procesos y procedimientos de una empresa constructora: caso Construecuador

    OpenAIRE

    Nicolalde Navarrete, José Diógenes Efrén

    2010-01-01

    El propósito de preparar esta tesis es proporcionar a las empresas constructoras en este caso CONSTRUECUADOR S. A., un documento que sirva de consulta y ayuda para la elaboración de los procesos y seguimiento del cumplimiento de los mismos. Este documento contiene: Un enfoque de la fundamentación teórica sobre la cual realizaremos nuestra investigación, analizaremos las técnicas de modelamiento de procesos, mencionaremos las principales organizaciones que regulan, modelan o sugieren ...

  5. El proceso de un cortometraje de animación

    OpenAIRE

    Romeu Marchán, Aida

    2016-01-01

    En este proyecto se recoge el estudio y la aplicación del proceso que debe seguirse en un cortometraje de animación 3D. El objetivo es conseguir un producto audiovisual que sirva como curva de autoaprendizaje para poder desarrollar un proyecto de animación desde la idea hasta la postproducción. A través de un cortometraje original llamado The Reaper’s Assistant se quiere completar y entender el proceso de guión, storyboard, animática, modelaje, diseño… de los personajes hasta s...

  6. en los procesos de investigación

    Directory of Open Access Journals (Sweden)

    José Arias Ordóñez

    2007-01-01

    Full Text Available El artículo presenta, inicialmente, dos enfoques de la gestión del conocimiento; posteriormente, muestra el desarrollo y la transformación de los procesos de creación de conocimiento y cómo con la apropiación y aplicación de teorías de gestión administrativa, la gestión del conocimiento se convierte en un intangible clave para las organizaciones; finalmente, se discuten algunos aspectos de la aplicación de un modelo de gestión del conocimiento en procesos de investigación.

  7. Seguridad pública, proceso penal acusatorio y juicio oral

    OpenAIRE

    Hesbert Benavente Chorres

    2011-01-01

    El artículo 20 de la Constitución Política de los Estados Unidos Mexicanos, reformado el 18 de junio de 2008, establece que el proceso penal será acusatorio y oral; debiéndose, en un plazo no mayor de ocho años contados a partir de la fecha antes mencionada, adoptar el citado proceso penal tanto a nivel federal como en cada una de las entidades federativas. Frente a ello, es objetivo del presente estudio establecer la relación entre este modelo de justicia penal con el tema de la seguridad pú...

  8. «Proceso de la literatura» peruana

    OpenAIRE

    Rovira Soler, José Carlos

    2009-01-01

    José Carlos Mariátegui revisa y actualiza en 1928 la mirada sobre la literatura peruana en un texto, «Proceso de la literatura», el último de los 7 ensayos de interpretación de la realidad peruana, a través del cual se conforma una nueva visión del complejo proceso de formación de la literatura nacional. La reflexión de Mariátegui resulta un hito imprescindible en el debate cultural de principios de siglo XX sobre la identidad peruana y una respuesta fundamental a las controversias suscitadas...

  9. Estudio del proceso de fundición del cobre

    OpenAIRE

    Toro Aguilar, Carlos N.; Wiesner I, Ignacio

    2009-01-01

    El presente trabajo enfoca el estudio sobre la disolución de gases y grado de oxidación en cobre líquido y para la condición de alcado; evaluando el proceso en cada caso mediante ensayos de planta, control químico y pruebas metalográficas. Una vez establecidos los parámetros adecuados del proceso, se procede a elaborar dos tipos de aleaciones con propiedades específicas, tales como Cobre – Cromo Norma UNS C81500 y Bronce al Estaño Norma C90500, haciendo variar en esta última el porcentaje...

  10. Parenteral Nutrition and Intestinal Failure.

    Science.gov (United States)

    Bielawska, Barbara; Allard, Johane P

    2017-05-06

    Severe short bowel syndrome (SBS) is a major cause of chronic (Type 3) intestinal failure (IF) where structural and functional changes contribute to malabsorption and risk of micronutrient deficiencies. Chronic IF may be reversible, depending on anatomy and intestinal adaptation, but most patients require long-term nutritional support, generally in the form of parenteral nutrition (PN). SBS management begins with dietary changes and pharmacologic therapies taking into account individual anatomy and physiology, but these are rarely sufficient to avoid PN. New hormonal therapies targeting intestinal adaptation hold promise. Surgical options for SBS including intestinal transplant are available, but have significant limitations. Home PN (HPN) is therefore the mainstay of treatment for severe SBS. HPN involves chronic administration of macronutrients, micronutrients, fluid, and electrolytes via central venous access in the patient's home. HPN requires careful clinical and biochemical monitoring. Main complications of HPN are related to venous access (infection, thrombosis) and metabolic complications including intestinal failure associated liver disease (IFALD). Although HPN significantly impacts quality of life, outcomes are generally good and survival is mostly determined by the underlying disease. As chronic intestinal failure is a rare disease, registries are a promising strategy for studying HPN patients to improve outcomes.

  11. Haemorrhage and intestinal lymphoma

    Directory of Open Access Journals (Sweden)

    Attilia M. Pizzini

    2013-04-01

    Full Text Available Background: The prevalence of coeliac disease is around 1% in general population but this is often unrecognised. The classical presentation of adult coeliac disease is characterized by diarrhoea and malabsorption syndrome, but atypical presentations are probably more common and are characterized by iron deficiency anaemia, weight loss, fatigue, infertility, arthralgia, peripheral neuropathy and osteoporosis. Unusual are the coagulation disorders (prevalence 20% and these are due to vitamin K malabsorption (prolonged prothrombin time. Clinical case: A 64-year-old man was admitted to our Department for an extensive spontaneous haematoma of the right leg. He had a history of a small bowel resection for T-cell lymphoma, with a negative follow-up and he didn’t report any personal or familiar history of bleeding. Laboratory tests showed markedly prolonged prothrombin (PT and partial-thromboplastin time (PTT, corrected by mixing studies, and whereas platelet count and liver tests was normal. A single dose (10 mg of intravenous vitamin K normalized the PT. Several days before the patient had been exposed to a superwarfarin pesticide, but diagnostic tests for brodifacoum, bromadiolone or difenacoum were negative. Diagnosis of multiple vitamin K-dependent coagulationfactor deficiencies (II, VII, IX, X due to intestinal malabsorption was made and coeliac disease was detected. Therefore the previous lymphoma diagnosis might be closely related to coeliac disease. Conclusions: A gluten free diet improves quality of life and restores normal nutritional and biochemical status and protects against these complications.

  12. [Malaria and intestinal protozoa].

    Science.gov (United States)

    Rojo-Marcos, Gerardo; Cuadros-González, Juan

    2016-03-01

    Malaria is life threatening and requires urgent diagnosis and treatment. Incidence and mortality are being reduced in endemic areas. Clinical features are unspecific so in imported cases it is vital the history of staying in a malarious area. The first line treatments for Plasmodium falciparum are artemisinin combination therapies, chloroquine in most non-falciparum and intravenous artesunate if any severity criteria. Human infections with intestinal protozoa are distributed worldwide with a high global morbid-mortality. They cause diarrhea and sometimes invasive disease, although most are asymptomatic. In our environment populations at higher risk are children, including adopted abroad, immune-suppressed, travelers, immigrants, people in contact with animals or who engage in oral-anal sex. Diagnostic microscopic examination has low sensitivity improving with antigen detection or molecular methods. Antiparasitic resistances are emerging lately. Copyright © 2016 Elsevier España, S.L.U. y Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.

  13. Adult intestinal failure

    Energy Technology Data Exchange (ETDEWEB)

    Davidson, J., E-mail: Jdavidson@doctors.org.u [Salford Royal Hospital, Salford (United Kingdom); Plumb, A.; Burnett, H. [Salford Royal Hospital, Salford (United Kingdom)

    2010-05-15

    Intestinal failure (IF) is the inability of the alimentary tract to digest and absorb sufficient nutrition to maintain normal fluid balance, growth, and health. It commonly arises from disease affecting the mesenteric root. Although severe IF is usually managed in specialized units, it lies at the end of a spectrum with degrees of nutritional compromise being widely encountered, but commonly under-recognized. Furthermore, in the majority of cases, the initial enteric insult occurs in non-specialist IF centres. The aim of this article is to review the common causes of IF, general principles of its management, some commoner complications, and the role of radiology in the approach to a patient with severe IF. The radiologist has a crucial role in helping provide access for feeding solutions (both enteral and parenteral) and controlling sepsis (via drainage of collections) in an initial restorative phase of treatment, whilst simultaneously mapping bowel anatomy and quality, and searching for disease complications to assist the clinicians in planning a later, restorative phase of therapy.

  14. [Intestinal failure: from adaptation to transplantation].

    Science.gov (United States)

    Messing, B; Corcos, O; Amiot, A; Joly, F

    2009-01-01

    Optimised Home Parenteral Nutrition is still, after 35 years of progress, the of benign but chronic Intestinal Failure. A better recognition of chronic Intestinal Failure, in its multiple facets, is warranted for a better approach of associated treatment to Home Parenteral Nutrition, i.e., intestinal trophic factors (growth hormone, Glucagon Like Peptide-2), rehabilitative surgery (reestablishment of colonic continuity, reverse jejunal segment in severe short gut type II) and/or reconstructive surgery (intestinal transplantation for end stage intestinal failure patients). Boundaries of permanent, judged irreversible, intestinal failure will be certainly modified in the following years by combining the various and effective therapies which optimise management by ameliorating absorption of the remnant short gut. The work done on short bowel syndrome in the past 20 years should be done in the next years for chronic-intestinal - pseudo-obstruction patients presenting with intestinal failure on a large European scale because chronic-intestinal - pseudo-obstruction is a group of heterogeneous but rare intestinal diseases. Intestinal transplantation is now a mature therapy with formal indication especially in case of Home Parenteral Nutrition failure (mainly Home Parenteral Nutrition-associated severe liver disease) where combined Liver-intestine transplantation is indicated before end-stage liver failure occurs. For high-risk patients, "preemptive" indication for intestinal transplantation alone will be discussed before home parenteral nutrition complications occur. No doubt that, for improving overall outcome in intestinal failure patients, reference centres should have in expert hands the whole spectrum of medicosurgical therapies for intestinal failure.

  15. COMUNICACIÓN EN PROCESOS DE TRABAJO

    Directory of Open Access Journals (Sweden)

    María Dolores Gil Montelongo

    2009-09-01

    Hidden="false" UnhideWhenUsed="false" QFormat="true" Name="Subtle Emphasis" />

    Se propone un modelo de comunicación que desarrolla un procedimiento, el cual,  apoyándose en los mapas de proceso y los diagramas de flujo informativo, permite establecer las matrices de comunicación para desarrollar las interacciones entre actividades y procesos, y mejorar los resultados.  Lograr este propósito puede conformar el inicio de la construcción de un modelo de comunicación organizacional

  16. [Interaction between humans and intestinal bacteria as a determinant for intestinal health : intestinal microbiome and inflammatory bowel diseases].

    Science.gov (United States)

    Haller, Dirk; Hörmannsperger, G

    2015-02-01

    Recent scientific results underline the importance of the intestinal microbiome, the totality of all intestinal microbes and their genes, for the health of the host organism. The intestinal microbiome can therefore be considered as a kind of "external organ". It has been shown that the intestinal microbiota is a complex and dynamic ecosystem that influences host immunity and metabolism beyond the intestine. The composition and functionality of the intestinal microbiota is of major importance for the development and maintenance of intestinal functions. Inflammatory bowel diseases (IBD) are characterized by dysregulated interactions between the host and its microbiota.The present contribution summarizes current knowledge of the composition and development of the intestinal microbiome and gives an overview of the bidirectional interaction between host and microbiota. The contribution informs about insights regarding the role of the intestinal microbiota in IBD and finally discusses the protective potential of microbial therapies in the context of IBD.

  17. Proceso contencioso-administrativo: emplazamiento personal de los codemandados

    OpenAIRE

    Gascón Inchausti, Fernando

    1998-01-01

    Comentario a la Sentencia del Tribunal Constitucional 192/1997, de 11 de noviembre de 1997, acerca de la necesidad de que todos los sujetos que reciben la consideración legal de codemandados en un proceso contencioso-administrativo sean emplazados personalmente.

  18. Intestinal circulation during inhalation anesthesia

    International Nuclear Information System (INIS)

    Tverskoy, M.; Gelman, S.; Fowler, K.C.; Bradley, E.L.

    1985-01-01

    This study was designed to evaluate the influence of inhalational agents on the intestinal circulation in an isolated loop preparation. Sixty dogs were studied, using three intestinal segments from each dog. Selected intestinal segments were pumped with aortic blood at a constant pressure of 100 mmHg. A mixture of 86 Rb and 9-microns spheres labeled with 141 Ce was injected into the arterial cannula supplying the intestinal loop, while mesenteric venous blood was collected for activity counting. A very strong and significant correlation was found between rubidium clearance and microsphere entrapment (r = 0.97, P less than 0.0001). Nitrous oxide anesthesia was accompanied by a higher vascular resistance (VR), lower flow (F), rubidium clearance (Cl-Rb), and microspheres entrapment (Cl-Sph) than pentobarbital anesthesia, indicating that the vascular bed in the intestinal segment was constricted and flow (total and nutritive) decreased. Halothane, enflurane, and isoflurane anesthesia were accompanied by a much lower arteriovenous oxygen content difference (AVDO 2 ) and oxygen uptake than pentobarbital or nitrous oxide. Compared with pentobarbital, enflurane anesthesia was not accompanied by marked differences in VR, F, Cl-Rb, and Cl-Sph; halothane at 2 MAC decreased VR and increased F and Cl-Rb while isoflurane increased VR and decreased F. alpha-Adrenoceptor blockade with phentolamine (1 mg . kg-1) abolished isoflurane-induced vasoconstriction, suggesting that the increase in VR was mediated via circulating catecholamines

  19. Modeling intestinal disorders using zebrafish.

    Science.gov (United States)

    Zhao, X; Pack, M

    2017-01-01

    Although the zebrafish was initially developed as a model system to study embryonic development, it has gained increasing attention as an advantageous system to investigate human diseases, including intestinal disorders. Zebrafish embryos develop rapidly, and their digestive system is fully functional and visible by 5days post fertilization. There is a large degree of homology between the intestine of zebrafish and higher vertebrate organisms in terms of its cellular composition and function as both a digestive and immune organ. Furthermore, molecular pathways regulating injury and immune responses are highly conserved. In this chapter, we provide an overview of studies addressing developmental and physiological processes relevant to human intestinal disease. These studies include those related to congenital disorders, host-microbiota interactions, inflammatory diseases, motility disorders, and intestinal cancer. We also highlight the utility of zebrafish to functionally validate candidate genes identified through mutational analyses and genome-wide association studies, and discuss methodologies to investigate the intestinal biology that are unique to zebrafish. Copyright © 2017 Elsevier Inc. All rights reserved.

  20. Isotopic identification of intestinal strangulation

    International Nuclear Information System (INIS)

    Anderson, M.C.; Selby, J.B.

    1982-01-01

    A small series of eleven dogs prepared with a strangulating segment of jejunum demonstrated that a radionuclide, 99 mTc-labelled albumin, concentrates in the lumen and bowel wall of the affected intestinal segment. Modern scanning equipment accurately localized the strangulating loop. This technique has the potential of identifying patients with intestinal obstruction, in whom strangulation is a factor, prior to the development of impaired arterial inflow and frank gangrene. These findings confirmed earlier obstructions that were reported when nuclear scanning instrumentation was less sophisticated. Identification of patients at risk for intestinal strangulation requires a high index of suspicion. Excruciating cramping abdominal pain out of proportion to physical findings, roentgenogram evidence, and laboratory studies should alert the physician to the possibility of intestinal ischemia and closed loop obstruction. Radionuclide scanning in such cases may be of assistance in defining or excluding the diagnosis of a strangulating mechanism. The test is simple, relatively economical, and represents a low risk procedure to patients. It would have no place when the classic physical and laboratory findings of intestinal infarction are present

  1. Isotopic identification of intestinal strangulation

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, M.C.; Selby, J.B.

    1982-12-01

    A small series of eleven dogs prepared with a strangulating segment of jejunum demonstrated that a radionuclide, /sup 99/mTc-labelled albumin, concentrates in the lumen and bowel wall of the affected intestinal segment. Modern scanning equipment accurately localized the strangulating loop. This technique has the potential of identifying patients with intestinal obstruction, in whom strangulation is a factor, prior to the development of impaired arterial inflow and frank gangrene. These findings confirmed earlier obstructions that were reported when nuclear scanning instrumentation was less sophisticated. Identification of patients at risk for intestinal strangulation requires a high index of suspicion. Excruciating cramping abdominal pain out of proportion to physical findings, roentgenogram evidence, and laboratory studies should alert the physician to the possibility of intestinal ischemia and closed loop obstruction. Radionuclide scanning in such cases may be of assistance in defining or excluding the diagnosis of a strangulating mechanism. The test is simple, relatively economical, and represents a low risk procedure to patients. It would have no place when the classic physical and laboratory findings of intestinal infarction are present.

  2. Galanin and vasoactive intestinal polypeptide

    DEFF Research Database (Denmark)

    Harling, H; Messell, T; Poulsen, Steen Seier

    1991-01-01

    By immunohistochemistry and double staining technique, almost complete coexistence of galanin-like immunoreactivity (GAL-LI) and vasoactive intestinal polypeptide-like immunoreactivity (VIP-LI) was demonstrated in submucosal ganglionic cells and mucosal nerve fibers of the porcine ileum. The rele......By immunohistochemistry and double staining technique, almost complete coexistence of galanin-like immunoreactivity (GAL-LI) and vasoactive intestinal polypeptide-like immunoreactivity (VIP-LI) was demonstrated in submucosal ganglionic cells and mucosal nerve fibers of the porcine ileum...

  3. Intestinal Microbiota Influences Non-intestinal Related Autoimmune Diseases

    Directory of Open Access Journals (Sweden)

    Maria C. Opazo

    2018-03-01

    Full Text Available The human body is colonized by millions of microorganisms named microbiota that interact with our tissues in a cooperative and non-pathogenic manner. These microorganisms are present in the skin, gut, nasal, oral cavities, and genital tract. In fact, it has been described that the microbiota contributes to balancing the immune system to maintain host homeostasis. The gut is a vital organ where microbiota can influence and determine the function of cells of the immune system and contributes to preserve the wellbeing of the individual. Several articles have emphasized the connection between intestinal autoimmune diseases, such as Crohn's disease with dysbiosis or an imbalance in the microbiota composition in the gut. However, little is known about the role of the microbiota in autoimmune pathologies affecting other tissues than the intestine. This article focuses on what is known about the role that gut microbiota can play in the pathogenesis of non-intestinal autoimmune diseases, such as Grave's diseases, multiple sclerosis, type-1 diabetes, systemic lupus erythematosus, psoriasis, schizophrenia, and autism spectrum disorders. Furthermore, we discuss as to how metabolites derived from bacteria could be used as potential therapies for non-intestinal autoimmune diseases.

  4. Gintonin absorption in intestinal model systems

    Directory of Open Access Journals (Sweden)

    Byung-Hwan Lee

    2018-01-01

    Conclusion: The present study shows that gintonin could be absorbed in the intestine through transcellular and paracellular diffusion, and active transport. In addition, the lipid component of gintonin might play a key role in its intestinal absorption.

  5. Microbiota, intestinal immunity, and mouse bustle

    OpenAIRE

    Kruglov, A.; Nedospasov, S.

    2014-01-01

    The composition of the intestinal microbiota is regulated by the immune system. This paper discusses the role of cytokines and innate immunity lymphoid cells in the intestinal immune regulation by means of IgA.

  6. Influencia del crowdsourcing en los procesos de las organizaciones

    OpenAIRE

    Planuch Prats, Carles; Salvador Vallès, Ramon

    2012-01-01

    En los últimos años diferentes áreas de investigación orientadas a la administración de empresa han vuelto su mirada hacía el fenómeno “Web 2.0” y “Web 3.0”. En el 2006 McAfee ya introdujo el término Empresa 2.0 para definir las tecnologías 2.0 aplicadas a procesos de negocio. Este artículo analiza la incidencia que sobre la innovación en las organizaciones tienen factores como la inteligencia colectiva, crowdsourcing (Howe 2006) y las herramientas Web 2.0 en sus procesos....

  7. CUERPOS DE MUJERES: PROCESOS DE DESVICTIMIZACIÓN

    Directory of Open Access Journals (Sweden)

    Mayra Solanye Galindo Huertas

    2017-01-01

    Full Text Available A través de la revisión, relectura y análisis de las investigaciones con grupos de mujeres de Tunja Boyacá Colombia, durante el periodo 2004- 2011, realizadas por el Grupo de Investigación Exclusiones y Resistencias en el Cuidado de la Salud-GERCUS y el Instituto Latinoamericano de Investigaci ón en el Cuidado de la Salud-ILICS, se exploran dos aspectos. El primero relacionado con el reconocimiento social y autoreconocimiento de las mujeres como víctimas y el segundo, concerniente a los procesos de superación de la condición de víctima. Ambos son sistematizados y discutidos a la luz de lo que hemos comprendido como procesos de desvictimización de las mujeres que han pasado por distintas situaciones de violencia.

  8. Treatment Option Overview (Small Intestine Cancer)

    Science.gov (United States)

    ... all of an organ that contains cancer. The resection may include the small intestine and nearby organs (if the cancer has spread). The doctor may remove the section of the small intestine that contains cancer and perform an anastomosis (joining the cut ends of the intestine together). ...

  9. General Information about Small Intestine Cancer

    Science.gov (United States)

    ... all of an organ that contains cancer. The resection may include the small intestine and nearby organs (if the cancer has spread). The doctor may remove the section of the small intestine that contains cancer and perform an anastomosis (joining the cut ends of the intestine together). ...

  10. Abdominal tuberculosis presenting as intestinal obstruction- Case ...

    African Journals Online (AJOL)

    One of the complications of abdominal tuberculosis is intestinal obstruction, which can be acute, chronic or acute on chronic. Other complications include intestinal haemorrhage, perforation of the intestine (rare), faecal fistula, cold abscess formation, mal-absorption syndrome and dissemination of the tuberculosis to other ...

  11. Exercise and the gastro-intestinal tract

    African Journals Online (AJOL)

    on perfonnance and me value of cardiovascular training in improving performance in aerobic sports is well recognised. The role of me gastro-intestinal tracr, bom as a limiting and sustaining facror in aerobic exercises, is less well appreciared. Gastro-intestinal symptoms. The spectrum of gastro-intestinal effecrs of exercise ...

  12. Childhood intestinal obstruction in Northwestern Nigeria

    African Journals Online (AJOL)

    of childhood intestinal obstruction in this study agrees with those reportedis'gi m3 from other parts of the coun- try. Mortality from childhood intestinal obstruction is still high in our environment. References. 1. Otu AA. Tropical surgical abdominal emergencies: acute intestinal obstruction. Postgrad. Doctor (Afr) 1992; 14: 51. 2.

  13. Protein malnutrition and metronidazole induced intestinal bacterial ...

    African Journals Online (AJOL)

    STORAGESEVER

    2008-09-17

    Sep 17, 2008 ... The gastrointestinal tract serves as a potent barrier that prevents luminal bacteria from entering the host. This barrier function is maintained by a well-balanced intestinal flora, an unaltered perme- ability of the intestinal mucosa, and a normal functioning immune system. Furthermore, the intestinal mucosa, in.

  14. Childhood intestinal obstruction in Northwestern Nigeria | Uba ...

    African Journals Online (AJOL)

    Background: Intestinal obstruction is a common cause of childhood surgical emergency in the tropics. The aim of this paper was to assess the pattern and the outcome of mangement of intestinal obstruction in Nigerian children. Study design: The clinical reccords of all the cases of childhood intestinal obstructions managed ...

  15. The TNO gastro-intestinal model (TIM)

    NARCIS (Netherlands)

    Minekus, M.

    2015-01-01

    The TNO Gastro–Intestinal Model (TIM) is a multi–compartmental model, designed to realistically simulate conditions in the lumen of the gastro–intestinal tract. TIM is successfully used to study the gastro–intestinal behavior of a wide variety of feed, food and pharmaceutical products. Experiments

  16. La Universidad del Zulia frente al proceso de transformación organizacional. Perspectiva de algunos actores del proceso

    Directory of Open Access Journals (Sweden)

    Juliana Ferrer

    2002-01-01

    Full Text Available La gerencia universitaria de hoy, requiere asumir un proceso de transformación organizacional, que le permita describir un equilibrio entre su identidad institucional y los cambios sustanciales exigidos desde todos sus ámbitos, a fin de mejorar los procesos académicos, cohesionar con éxito las funciones básicas y por ende lograr la calidad académica deseada. Surge como inquietud el presente artículo el cual pretende indagar sobre algunos esfuerzos que la Universidad del Zulia ha adelantado en este sentido, pero sobre todo hacer énfasis en la perspectiva de algunos actores del proceso, representados por el personal docente y de investigación, que para el período 2000-2001 se desempeño como personal directivo Para la recolección de los datos se asumió en primer término la técnica cualitativa del grupo focal, permitiendo así lograr suficiente información para aplicar luego, una muestra probabilística que arrojó un tamaño de 39 unidades con un nivel de confianza del 95%. Se concluye que los gerentes universitarios están conscientes de los problemas de carácter operativo que obstaculizan el proceso de cohesión exitosa de las funciones básicas. Sin embargo, no evidencian conocimiento exhaustivo sobre el desarrollo de procesos gerenciales, para el logro de los cursos de acción enunciados por esos mismos actores. Se recomienda sobre la necesidad de formar una gerencia universitaria sólida, en el compromiso de la labor constante en materia de información y conocimiento, de tal forma que los cambios implantados sean percibidos de manera objetiva, internalizados y compartidos por la comunidad universitaria, en la búsqueda de que ellos se conviertan en piezas del proceso de cambio institucional.

  17. El procedimiento sumario administrativo a la luz del debido proceso

    OpenAIRE

    Hernández Velásquez, Boris Isaac

    2014-01-01

    El presente es un estudio del procedimiento sumario administrativo previsto en la normativa ecuatoriana a efecto de determinar si se ajusta a los principios del debido proceso procesal. Para tal efecto, primeramente ha sido necesario indagar en la naturaleza jurídica del sumario administrativo, para lo cual se ha partido del estudio del procedimiento administrativo, su definición y particularidades, así como los principios que lo rigen dentro del ámbito administrativo. Posteriormente se ha re...

  18. Los procesos curriculares de postgrado: una necesidad del tercer milenio

    Directory of Open Access Journals (Sweden)

    Homero Fuentes González

    1997-10-01

    Full Text Available Ante el problema que presentan las instituciones educacionales universitarias en el desarrollo de la formación postgradual de sus egresados en el presente artículo se da un enfoque sistémico del postgrado y se caracterizan sus diferentes figuras, su concepción y organización en una contextualización de los procesos universitarios.

  19. Suma o resta del proceso de investigación científica estudiantil al proceso sustantivo de investigación científica

    OpenAIRE

    Mariluz Llanes-Font; Mayra Moreno-Pino; Ernesto Lorenzo-Llanes

    2011-01-01

    Se analiza que el proceso de investigación constituye uno de los procesos sustantivos en las universidades, al igual que el de formación y extensión. En el artículo se argumenta la necesidad de revisar y perfeccionar el proceso de investigación científica estudiantil desde lo curricular y extracurricular. Se señala la relevancia de desplegarse con enfoque a proceso, particularizando en las transformaciones internas del mismo y en su interrelación con el entorno. Enfatiza en que es esencial qu...

  20. Las Olas del Renovación del Processo, Neoconstitucionalismo y el Proceso Democrático en el Nuevo Código de Proceso Civil

    OpenAIRE

    Bianchini, Marcos Paulo Andrade; Borba, Alderico Kleber De

    2016-01-01

    Este trabajo pretende revisar olas del renovación del proceso, neoconstitucionalismo y el proceso democrático en el nuevo código de procedimiento civil. En este trabajo se utilizaron los métodos deductivos y dogmáticos y bibliográficos. Gracias-si proceso metodológico histórico y comparativo. La investigación se divide en tres partes: olas de renovación proceso, contradictorio tridimensional y democrática en nuevo código de Procedimiento Civil-NCPC. Actualmente la tercera ola renovatória el p...

  1. Entomoftoromicose intestinal: relato de caso

    Directory of Open Access Journals (Sweden)

    Fábia Aparecida Carvalho

    1997-02-01

    Full Text Available Os autores relatam um caso de entomoftoromicose intestinal causada por Entomophthorales, em indivíduo de 19 anos, agricultor e sem doença associada. O paciente foi submetido a ressecção intestinal e o diagnóstico foi feito após análise da peça cirúrgica. Após revisão da literatura, são discutidos a evolução clínica, as características clinicopatológicas, as dificuldades no diagnóstico e o tratamento dessa entidade rara.A case of intestinal entomophthoramycosis caused by Entomophthorales in a man with 19 years-old, farmer and without associated disease. The patient was submitted to a intestinal ressection and diagnosis was carried through after analisys of the surgical specimen. After a review of the literature, the clinical evolution, clinico-pathologic features, difficulties in diagnosis and treatment are discussed.

  2. Diversity of insect intestinal microflora

    Czech Academy of Sciences Publication Activity Database

    Mrázek, Jakub; Štrosová, Lenka; Fliegerová, Kateřina; Kott, T.; Kopečný, Jan

    2008-01-01

    Roč. 53, č. 3 (2008), s. 229-233 ISSN 0015-5632 R&D Projects: GA ČR GA303/06/0974 Institutional research plan: CEZ:AV0Z50450515 Keywords : insect intestinal microflora Subject RIV: EE - Microbiology, Virology Impact factor: 1.172, year: 2008

  3. Circadian disorganization alters intestinal microbiota.

    Science.gov (United States)

    Voigt, Robin M; Forsyth, Christopher B; Green, Stefan J; Mutlu, Ece; Engen, Phillip; Vitaterna, Martha H; Turek, Fred W; Keshavarzian, Ali

    2014-01-01

    Intestinal dysbiosis and circadian rhythm disruption are associated with similar diseases including obesity, metabolic syndrome, and inflammatory bowel disease. Despite the overlap, the potential relationship between circadian disorganization and dysbiosis is unknown; thus, in the present study, a model of chronic circadian disruption was used to determine the impact on the intestinal microbiome. Male C57BL/6J mice underwent once weekly phase reversals of the light:dark cycle (i.e., circadian rhythm disrupted mice) to determine the impact of circadian rhythm disruption on the intestinal microbiome and were fed either standard chow or a high-fat, high-sugar diet to determine how diet influences circadian disruption-induced effects on the microbiome. Weekly phase reversals of the light:dark (LD) cycle did not alter the microbiome in mice fed standard chow; however, mice fed a high-fat, high-sugar diet in conjunction with phase shifts in the light:dark cycle had significantly altered microbiota. While it is yet to be established if some of the adverse effects associated with circadian disorganization in humans (e.g., shift workers, travelers moving across time zones, and in individuals with social jet lag) are mediated by dysbiosis, the current study demonstrates that circadian disorganization can impact the intestinal microbiota which may have implications for inflammatory diseases.

  4. Milk products and intestinal health

    NARCIS (Netherlands)

    Van der Meer, R; Bovee-Oudenhoven, IMJ; Sesink, ALA; Kleibeuker, JH

    Milk products may improve intestinal health by means of the cytoprotective effects of their high calcium phosphate (CaPi) content. We hypothesized that this cytoprotection may increase host defenses against bacterial infections as well as decrease colon cancer risk. This paper summarizes our studies

  5. [Chronic intestinal pseudo-obstruction].

    Science.gov (United States)

    Joly, Francisca; Amiot, Aurélien; Coffin, Benoît; Lavergne-Slove, Anne; Messing, Bernard; Bouhnik, Yoram

    2006-01-01

    Chronic intestinal pseudo-obstruction (CIPO) is a disease characterized by episodes resembling mechanical obstruction in the absence of organic, systemic, or metabolic disorders. Pseudo-obstruction is an uncommon condition and can result from primary (40%) or secondary (60%) causes. The most common symptoms are nausea, vomiting, abdominal distension, abdominal pain and constipation or diarrhea. These symptoms are usually present many years before CIPO diagnosis. They can lead to severe electrolyte disorders and malnutrition. Principles for management of patients with CIPO are: to establish a correct clinical diagnosis in excluding mechanical obstruction; to perform a symptomatic and physiologic assessment of the gastrointestinal tract involved; to look for extra-intestinal manifestations, especially for myopathy and neuropathy; to discuss in some cases a surgery for full-thickness intestinal biopsies, and/or a neuromuscular biopsy in case of mitochondrial cytopathy suspicion. The management is primarily focused on symptom control and nutritional support to prevent weight loss and malnutrition. Treatment of CIPO includes prokinetic agents which may help to reduce gastrointestinal symptoms Courses of antibiotics may be needed in patients with symptoms suggestive of bacterial overgrowth. When necessary, enteral nutrition is preferred. In carefully selected patients, feeding jejunostomy with or without decompression gastrostomy may be tried. Long term parenteral nutrition should be reserved for patients who can not tolerate enteral nutrition. Intestinal transplantation can be discussed in selected patients.

  6. INTESTINAL PERMEABILITY IN PEDIATRIC GASTROENTEROLOGY

    NARCIS (Netherlands)

    VANELBURG, RM; UIL, JJ; DEMONCHY, JGR; HEYMANS, HSA

    1992-01-01

    The role of the physiologic barrier function of the small bowel and its possible role in health and disease has attracted much attention over the past decade. The intestinal mucosal barrier for luminal macromolecules and microorganism is the result of non-immunologic and immunologic defense

  7. Microcontainers for Intestinal Drug Delivery

    DEFF Research Database (Denmark)

    Tentor, Fabio; Mazzoni, Chiara; Keller, Stephan Sylvest

    Among all the drug administration routes, the oral one is the most preferred by the patients being less invasive, faster and easier. Oral drug delivery systems designed to target the intestine are produced by powder technology and capsule formulations. Those systems including micro- and nano...

  8. Procesos agroecológicos, en Ventaquemada Boyacá

    Directory of Open Access Journals (Sweden)

    Francisco Gracía

    2011-10-01

    Full Text Available La agroecología se debe entender como la interacción de factorespolíticos, sociales, culturales, económicos, medio ambientales, educativos y tecnológicos, así como de los procesos productivos que trazan el derrotero en el desarrollo de los pueblos. Mientras que la agricultura convencional estableció parámetros diferentesde producción, que alejaron la actividad agropecuaria del concepto de agroecología y la convirtieron en un negocio donde el deterioro de los recursos naturales es consecuencia del proceso productivo. De esta manera el presente trabajo busca identificar y analizar los contextos agroecológicos sucedidos en la vereda Supatá en Ventaquemada – Boyacá, que han influido en las familias. Para esto se establecieron como técnicas y herramientas la consulta dedocumentos estadísticos, talleres participativos, matriz (Dofa, mapeo, mapa de redes, matriz de plan acción, entrevistas semiestructuradas, observación no participante y diarios de campo. Así, se pudo establecer que las actividades agrícolas marcan el comportamiento de las personas, dejando notar que la agricultura de revolución verde, propuesta como proceso agroindustrial, promueve el individualismo a partir del monocultivo.

  9. Intestinal epithelium in inflammatory bowel disease

    DEFF Research Database (Denmark)

    Coskun, Mehmet

    2014-01-01

    homeostasis. Therefore, dysregulation within the epithelial layer can increase intestinal permeability, lead to abnormalities in interactions between IECs and immune cells in underlying lamina propria, and disturb the intestinal immune homeostasis, all of which are linked to the clinical disease course......The intestinal epithelium has a strategic position as a protective physical barrier to luminal microbiota and actively contributes to the mucosal immune system. This barrier is mainly formed by a monolayer of specialized intestinal epithelial cells (IECs) that are crucial in maintaining intestinal...

  10. Microbiota intestinal, probióticos y prebióticos

    Directory of Open Access Journals (Sweden)

    Carlos David Castañeda Guillot

    2017-12-01

    Full Text Available La microbiota intestinal es el elemento fundamental del “Ecosistema Intestinal”, cuyas acciones tienen un efecto beneficioso para la salud, al participar de forma activa en los procesos de digestión de nutrientes asociado a sus mecanismos sobre la homeostasis y la inmunidad del intestino. Los probióticos y prebióticos juegan un rol decisivo en la modulación de la microbiota intestinal y han demostrado sus beneficios para el tratamiento de distintas enfermedades intestinales y extra-intestinales. Se realizó una búsqueda en bases documentales de PubMed, SciELO y Latindex de publicaciones relacionadas con la microbiota intestinal, probióticos y prebióticos hasta el 30 junio 2017. Son actualizados los criterios relacionados con las funciones de la microbiota intestinal, el proceso de implantación a partir del nacimiento, el desarrollo acelerado en su composición, los distintos factores que influencian en su diversidad y estabilidad para mantener un estado de eubiosis en el curso de la vida. El desequlibrio de la misma (disbiosis es un elemento de importancia en la producción de afecciones intestinales y extra-intestinales agudas y crónicas. Se revisaron los probióticos y prebióticos, sus ventajas, tipos, indicaciones y las formas de obtención de los prebióticos. El papel de la microbiota intestinal como órgano metabólico por sus múltiples funciones, en especial la homeostasis e inmunidad intestinal y sus beneficios para la salud son revisados. La participación de los probióticos y prebióticos como terapéutica y sus efectos en enfermedades intestinales y extra-intestinales relacionadas con la microbiota y su modulación son examinados por su importancia en la práctica médica.

  11. Teoría de restricciones para procesos de manufactura

    Directory of Open Access Journals (Sweden)

    Gabriela Villagómez

    2012-06-01

    Full Text Available La empresa “Productos Alexander” fabricante de snacks de la ciudad de Quito, tiene un sistema de producción que no permite el abastecimiento de los pedidos de sus clientes reflejando un índice de servicio al cliente de 89,58% ya que sus procesos están trabajando con capacidades que no se encuentran correctamente programadas, en vista de tal razón el objetivo de esta investigación es proponer un sistema de mejora continua con el fin de aumentar y efectivizar específicamente la producción de snacks de papas fritas utilizando la Teoría de Restricciones (TOC como metodología científica. Se realizó la medición de capacidad de cada una de las operaciones que componen el proceso de elaboración de snacks y se identificó la restricción en el proceso de fritura, que no estaba trabajando el 100% del tiempo en la jornada diaria limitando así la capacidad de la fábrica, por lo que se optó por explotar la restricción para eliminarla. La propuesta planteada para explotar la restricción consiste en una mejor programación de la producción, reducción de lote de transferencia de proceso a proceso, programación de la cantidad de trabajo para cada uno de los operarios en la jornada, la preparación del proceso y la fijación de turnos en la hora de almuerzo de los operarios lo que contribuye a agilizar el proceso de fritura y permitir que trabaje a su máxima capacidad el 100% del tiempo.Dicha propuesta se puede considerar como una solución al problema y así mejorar los niveles de producción de la empresa, tomando en cuenta que en base a los indicadores de TOC el Beneficio Neto de la empresa aumentaría de $15 333.09 a $ 17 392.14 al cumplir en cantidad y a tiempo todos los pedidos de los clientes.Abstract:The company "Products Alexander" snack manufacturer in the city of Quito, has a production system that cannot supply customer orders, with a customer service index of 89,58%, also their processes are working with capabilities that

  12. A etiological factors in mechanical intestinal obstruction

    International Nuclear Information System (INIS)

    Asad, S.; Khan, H.; Khan, I.A.; Ghaffar, S.; Rehman, Z.U.

    2012-01-01

    Background: Intestinal obstruction occurs when the normal flow of intestinal contents is interrupted. The most frequent causes of intestinal obstruction are postoperative adhesions and hernias, which cause extrinsic compression of the intestine. Less frequently, tumours or strictures of the bowel can cause intrinsic blockage. Objective of the study was to find out the various a etiological factors of mechanical intestinal obstruction and to evaluate the morbidity and mortality in adult patients presenting to Surgical 'A' unit of Ayub teaching hospital with mechanical intestinal obstruction. Methods: This cross-sectional study was conducted from March 2009 to September, 2009. All patients presenting with intestinal obstruction and were above the age of 12 years were included in the study. Patients with non-mechanical obstruction were excluded from the study and those who responded to conservative measures were also excluded. Results: A total of 36 patients with age ranging from 12 to 80 years (Mean age 37.72+-19.74 years) and male to female ratio of 1.77:1, were treated for mechanical intestinal obstruction. The most common cause for mechanical intestinal obstruction was adhesions (36.1%). Intestinal tuberculosis was the second most common cause (19.4%), while hernias and sigmoid volvulus affected 13.9% patients each. Malignancies were found in 5.6% cases. Conclusion: Adhesions and Tuberculosis are the leading causes of mechanical intestinal obstruction in Pakistan. Although some patients can be treated conservatively, a substantial portion requires immediate surgical intervention. (author)

  13. Intestinal Epithelial Sirtuin 1 Regulates Intestinal Inflammation During Aging in Mice by Altering the Intestinal Microbiota.

    Science.gov (United States)

    Wellman, Alicia S; Metukuri, Mallikarjuna R; Kazgan, Nevzat; Xu, Xiaojiang; Xu, Qing; Ren, Natalie S X; Czopik, Agnieszka; Shanahan, Michael T; Kang, Ashley; Chen, Willa; Azcarate-Peril, M Andrea; Gulati, Ajay S; Fargo, David C; Guarente, Leonard; Li, Xiaoling

    2017-09-01

    Intestinal epithelial homeostasis is maintained by complex interactions among epithelial cells, commensal gut microorganisms, and immune cells. Disruption of this homeostasis is associated with disorders such as inflammatory bowel disease (IBD), but the mechanisms of this process are not clear. We investigated how Sirtuin 1 (SIRT1), a conserved mammalian NAD + -dependent protein deacetylase, senses environmental stress to alter intestinal integrity. We performed studies of mice with disruption of Sirt1 specifically in the intestinal epithelium (SIRT1 iKO, villin-Cre+, Sirt1 flox/flox mice) and control mice (villin-Cre-, Sirt1 flox/flox ) on a C57BL/6 background. Acute colitis was induced in some mice by addition of 2.5% dextran sodium sulfate to drinking water for 5-9 consecutive days. Some mice were given antibiotics via their drinking water for 4 weeks to deplete their microbiota. Some mice were fed with a cholestyramine-containing diet for 7 days to sequester their bile acids. Feces were collected and proportions of microbiota were analyzed by 16S rRNA amplicon sequencing and quantitative PCR. Intestines were collected from mice and gene expression profiles were compared by microarray and quantitative PCR analyses. We compared levels of specific mRNAs between colon tissues from age-matched patients with ulcerative colitis (n=10) vs without IBD (n=8, controls). Mice with intestinal deletion of SIRT1 (SIRT1 iKO) had abnormal activation of Paneth cells starting at the age of 5-8 months, with increased activation of NF-κB, stress pathways, and spontaneous inflammation at 22-24 months of age, compared with control mice. SIRT1 iKO mice also had altered fecal microbiota starting at 4-6 months of age compared with control mice, in part because of altered bile acid metabolism. Moreover, SIRT1 iKO mice with defective gut microbiota developed more severe colitis than control mice. Intestinal tissues from patients with ulcerative colitis expressed significantly lower

  14. Intestinal perfusion in the study of intestinal absorption

    International Nuclear Information System (INIS)

    Baker, S.J.

    1976-01-01

    Several techniques for studying absorption by means of intestinal perfusion have been developed. While the principle is simple, the practice is complicated by absorption of the solvent and by excretion of fluid into the lumen. To improve reliability a ''marker'' is incorporated into the system; it should behave as nearly as possible like the nutrient of interest, except that it should be unabsorbable. A great many markers, including several labelled with radionuclides, have been developed for use with numerous nutrients, and perfusion methods using double or triple tubes or occlusive balloons have been tested. The perfusion technique is too complicated for routine diagnostic use, but it offers at present the only possibility of studying the function of defined sections of the small intestine in the intact human. (author)

  15. The Contributions of Human Mini-Intestines to the Study of Intestinal Physiology and Pathophysiology.

    Science.gov (United States)

    Yu, Huimin; Hasan, Nesrin M; In, Julie G; Estes, Mary K; Kovbasnjuk, Olga; Zachos, Nicholas C; Donowitz, Mark

    2017-02-10

    The lack of accessibility to normal and diseased human intestine and the inability to separate the different functional compartments of the intestine even when tissue could be obtained have held back the understanding of human intestinal physiology. Clevers and his associates identified intestinal stem cells and established conditions to grow "mini-intestines" ex vivo in differentiated and undifferentiated conditions. This pioneering work has made a new model of the human intestine available and has begun making contributions to the understanding of human intestinal transport in normal physiologic conditions and the pathophysiology of intestinal diseases. However, this model is reductionist and lacks many of the complexities of normal intestine. Consequently, it is not yet possible to predict how great the advances using this model will be for understanding human physiology and pathophysiology, nor how the model will be modified to include multiple other intestinal cell types and physical forces necessary to more closely approximate normal intestine. This review describes recent studies using mini-intestines, which have readdressed previously established models of normal intestinal transport physiology and newly examined intestinal pathophysiology. The emphasis is on studies with human enteroids grown either as three-dimensional spheroids or two-dimensional monolayers. In addition, comments are provided on mouse studies in cases when human studies have not yet been described.

  16. The intestinal microenvironment in sepsis.

    Science.gov (United States)

    Fay, Katherine T; Ford, Mandy L; Coopersmith, Craig M

    2017-10-01

    The gastrointestinal tract has long been hypothesized to function as "the motor" of multiple organ dysfunction syndrome. The gastrointestinal microenvironment is comprised of a single cell layer epithelia, a local immune system, and the microbiome. These three components of the intestine together play a crucial role in maintaining homeostasis during times of health. However, the gastrointestinal microenvironment is perturbed during sepsis, resulting in pathologic changes that drive both local and distant injury. In this review, we seek to characterize the relationship between the epithelium, gastrointestinal lymphocytes, and commensal bacteria during basal and pathologic conditions and how the intestinal microenvironment may be targeted for therapeutic gain in septic patients. Published by Elsevier B.V.

  17. Drug Transporters in the Intestine

    DEFF Research Database (Denmark)

    Steffansen, Bente

    2016-01-01

    that may impact drug absorption. Thus absorptive transporters may facilitate BA of APIs that are substrates/victims for the transporters and have permeability-limited absorption, i.e. those that are classified in the biopharmaceutics classification system (BCS) Class 3 and 4. On the other hand, exsorptive...... transporters may restrict BA of APIs that are victims for these efflux transporters, especially those APIs classified to have solubility-limited absorption, i.e. compounds in BCS Class 2 and 4. The aim of the present Chapter is to review drug transporters (DTs) present within the intestine and to discuss...... and exemplify their roles in drug absorption/exsorption and in drug-drug interactions (DDIs). Although focus in the present Chapter is on DTs that are mentioned in American and European regulatory guidances, the intestinal transporters for nutrients and endogens (endogenous compounds) are also briefly...

  18. [Chronic gastritis and intestinal metaplasia].

    Science.gov (United States)

    Castillo, T; Navarrete, J; Celestina, A

    1989-01-01

    Much has been written about gastric mucosae behavior and the occurrence of intestinal metaplasia. The aim of this paper is to learn something more about these matters in peruvian population. We selected 100 patients with endoscopically no localized lesions between 30 to 70 years of age. We took 8 samples of gastric mucosae in each patient which were carefully examined for the presence of inflammatory changes, settle the line type between antral and fundic mucosae and the frequency of intestinal metaplasia finding. The results showed disagreement between endoscopic and histological findings, so we conclude it is better to diagnose chronic gastritis on the basis of histological parameters. The line between antral and fundic mucosae was of the close type one found in 87% of all cases and it advanced proximally with increasing age. Intestinal metaplasia was present in 46% of the whole number of patients and the rate of occurrence increased in 50% over 50 years age. These findings will let us compare future investigations of gastric mucosae behavior with localized benign or malign lesions.

  19. Radiological manifestations of intestinal tuberculosis

    International Nuclear Information System (INIS)

    Im, Jae Hoon

    1974-01-01

    Radiological findings of 87 cases of intestinal tuberculosis are analyzed and presented. The diagnosis was based on histopathology in 29 cases, and on clinical ground and radiological findings in 58 cases. The radio of male and female patients was 4:6, and peak incidence is between 10 and 30. Abdominal pain, diarrhea, weight loss, fever and general weakness are frequent symptoms, and tenderness of abdomen, ascites with abdominal distension, malnutrition and emaciation are frequent signs of the patients. Laboratory investigation reveal anemia, raised ESR, hypoalbuminaemia and positive occult blood reaction in the stool in most of the patients. Chest film show activity pulmonary tuberculosis in only 1/3 patients. There is no pathognomonic radiological findings in intestinal tuberculosis and their manifestations are protean, and differentiation from other inflammatory diseases and malignant tumors in gastrointestinal tract is very difficult on radiological ground alone. However, in patients with complaining vague abdominal symptoms and signs, the radiological diagnosis is most certain means in the decision of existence of organic lesion and suggestion of tuberculosis in the gastrointestinal tract and its extent as yet. Multiplicity of the lesion, involvement of adjacent organ such as peritoneum or mesenteric lymph nodes, typical nodularity or irregularity of mesenteric border and existence of active pulmonary tuberculosis are the suggestive findings of intestinal tuberculosis. In the diagnosis of inflammatory disease or malignant tumor of gastrointestinal tract, the possibility of tuberculosis should be borne in mind, and vice versa

  20. [Intestinal parasitic diseases in children].

    Science.gov (United States)

    Mare, Anca; Man, A; Toma, Felicia; Székely, Edit; Lôrinczi, Lilla; Sipoş, Anca

    2007-01-01

    To compare the incidence of intestinal parasitosis between children with residence in urban and rural areas: to compare the efficacy of parasitologic diagnostic methods. In our study we included two lots of children. The first lot consisted in 74 children from rural areas from which we collected 44 samples of feces and 55 samples for the "Scotch tape" test. The second lot consisted in 214 children from urban areas from which we collected 44 samples of feces. We examined each sample of feces by three different methods. The study was performed between April to June 2006. The incidence of intestinal parasitosis increases in children from urban areas towards rural areas, and in children between 5 and 10 years. Ascariasis is the most frequent disease in both urban and rural areas. By examination of each fecal sample by three different methods, the number of positive cases increased. The residence in rural areas and age between 5 to 10 years are risk factors for intestinal parasitosis. The "Scotch tape" test was more efficient in Enterobius vermicularis infection than the methods performed from feces. We recommend using at the same time three diagnostic methods for feces examination to improve the diagnostic sensibility.

  1. Colon in acute intestinal infection.

    Science.gov (United States)

    Guarino, Alfredo; Buccigrossi, Vittoria; Armellino, Carla

    2009-04-01

    The colon is actively implicated in intestinal infections not only as a target of enteric pathogens and their products but also as a target organ for treatment. In the presence of diarrhea, both of osmotic and secretory nature, the colon reacts with homeostatic mechanisms to increase ion absorption. These mechanisms can be effectively exploited to decrease fluid discharge. A model of intestinal infections using rotavirus (RV) in colonic cells was set up and used to define a dual model of secretory and osmotic diarrhea in sequence. Using this model, antidiarrheal drugs were tested, namely zinc and the enkephalinase inhibitor racecadotril. Zinc was able to decrease the enterotoxic activity responsible for secretory diarrhea. It also inhibited the cytotoxic effect of RV. The mechanism of zinc was related at least in part to the activation of MAPK activity, but also a direct antiviral effect was observed. Racecadotril showed a potent and selective inhibition of active secretion, being particularly effective in the first phase of RV diarrhea. The use of drugs active at the colonic level, therefore, offers effective options to treat intestinal infections in childhood. In addition, the colon is the natural site of colonic microflora, a target of probiotic therapy, which is the first line of approach recommended by the European Society for Paediatric Gastroenterology, Hepatology and Nutrition to treat infectious diarrhea.

  2. PROCESOS DE EROSIÓN EN LOS BADLANDS ALICANTINOS

    Directory of Open Access Journals (Sweden)

    A. Cerdà i Bolinches

    1997-01-01

    Full Text Available Los procesos de erosión son muy activos en la provincia de Alicante debido a las reducidas e irregulares precipitaciones, al substrato altamente erosionable y al milenario uso antrópico. Estas condiciones dan lugar a la formación de zonas acarcavadas o badlands, los cuales contribuyen con elevados volúmenes de agua y sedimentos a los cauces. A partir de experimentos con lluvia simulada se estudian los procesos de erosión y se cuantifican sus tasas a escala de entre-regueros (< 1 m 2 en dos zonas de badlands típicos del territorio alicantino: Monnegre y Petrer. En general, las tasas de erosión y escorrentía son muy elevadas, lo que se debe al rápido encharcamiento y la inmediata formación de la escorrentía superficial con la lluvia. La zona de Monnegre presenta menores pérdidas de agua, suelo y solutos que la de Petrer, aunque las diferencias dentro de cada zona son mayores que entre ellas. La inexistencia de cubierta vegetal y fragmen- tos de roca da lugar a altas tasas de escorrentía (54% y concentración de sedimentos que oscilan entre 20 y 82 g l -1 , por lo que las tasas de erosión son muy altas (1,5 Kg m 2 h -1 . La pendiente es el factor más importante de las tasas de erosión en los badlands, a lo que hay que sumar el control químico de los procesos de erosión.

  3. Immunogenetic control of the intestinal microbiota.

    Science.gov (United States)

    Marietta, Eric; Rishi, Abdul; Taneja, Veena

    2015-07-01

    All vertebrates contain a diverse collection of commensal, symbiotic and pathogenic microorganisms, such as bacteria, viruses and fungi, on their various body surfaces, and the ecological community of these microorganisms is referred to as the microbiota. Mucosal sites, such as the intestine, harbour the majority of microorganisms, and the human intestine contains the largest community of commensal and symbiotic bacteria. This intestinal community of bacteria is diverse, and there is a significant variability among individuals with respect to the composition of the intestinal microbiome. Both genetic and environmental factors can influence the diversity and composition of the intestinal bacteria with the predominant environmental factor being diet. So far, studies have shown that diet-dependent differences in the composition of intestinal bacteria can be classified into three groups, called enterotypes. Other environmental factors that can influence the composition include antibiotics, probiotics, smoking and drugs. Studies of monozygotic and dizygotic twins have proven that genetics plays a role. Recently, MHC II genes have been associated with specific microbial compositions in human infants and transgenic mice that express different HLA alleles. There is a growing list of genes/molecules that are involved with the sensing and monitoring of the intestinal lumen by the intestinal immune system that, when genetically altered, will significantly alter the composition of the intestinal microflora. The focus of this review will be on the genetic factors that influence the composition of the intestinal microflora. © 2015 John Wiley & Sons Ltd.

  4. Immediate postconditioning during reperfusion attenuates intestinal injury.

    Science.gov (United States)

    Liu, Ke-Xuan; Li, Yun-Sheng; Huang, Wen-Qi; Chen, Shu-Qing; Wang, Zhong-Xin; Liu, Jia-Xin; Xia, Zhengyuan

    2009-05-01

    To test the hypothesis that immediate but not delayed ischemic postconditioning (IPo) during reperfusion attenuates intestinal injury, and that ischemic preconditioning (IPC) and IPo may confer synergy in intestinal protection. Prospective laboratory animal study with concurrent control. Adult Sprague-Dawley rats. Intestinal ischemia/reperfusion (II/R) injury in rats was produced by clamping superior mesenteric artery for 60 min followed by 60 min reperfusion; IPC was elicited by 10 min ischemia and 10 min reperfusion before index ischemia; IPo was performed by three cycles of 30 s reperfusion and 30 s ischemia initiated either immediately at the onset of reperfusion (IPo) or after reperfusion for 3 min (delayed-IPo). Combination of IPC and IPo was performed by combining both protocols. Intestinal ischemia/reperfusion resulted in significant intestinal injury evidenced as significant increase in Chiu's scores and wet-to-dry intestine weight ratio accompanied with increases in plasma levels of tumor necrosis factor-alpha and interleukin-6, as well as increases in the intestinal tissue lipid peroxidation product malonediadehyde and myeloperoxidase activity as compared to control animals (all P IPo or their combination (P IPo (P > 0.05). IPC and IPo showed synergistic protection compared with either protocol alone. Ischemic postconditioning reduces intestinal injury, in part, by inhibiting oxidative injury, neutrophils filtration and proinflammatory response. The early period of reperfusion is critical to intestinal protection by IPo, and intestinal protection with IPo can be enhanced by IPC.

  5. Intestinal microcirculatory dysfunction and neonatal necrotizing enterocolitis.

    Science.gov (United States)

    Zhang, Hong-yi; Wang, Fang; Feng, Jie-xiong

    2013-01-01

    Based on the observation that coagulation necrosis occurs in the majority of neonatal necrotizing enterocolitis (NEC) patients, it is clear that intestinal ischemia is a contributing factor to the pathogenesis of NEC. However, the published studies regarding the role of intestinal ischemia in NEC are controversial. The aim of this paper is to review the current studies regarding intestinal microcirculatory dysfunction and NEC, and try to elucidate the exact role of intestinal microcirculatory dysfunction in NEC. The studies cited in this review were mainly obtained from articles listed in Medline and PubMed. The search terms used were "intestinal microcirculatory dysfunction" and "neonatal necrotizing enterocolitis". Mainly original milestone articles and critical reviews written by major pioneer investigators in the field were selected. Immature regulatory control of mesentery circulation makes the neonatal intestinal microvasculature vulnerable. When neonates are subjected to stress, endothelial cell dysfunction occurs and results in vasoconstriction of arterioles, inflammatory cell infiltration and activation in venules, and endothelial barrier disruption in capillaries. The compromised vasculature increases circulation resistance and therefore decreases intestinal perfusion, and may eventually progress to intestinal necrosis. Intestinal ischemia plays an important role through the whole course of NEC. New therapeutic agents targeting intestinal ischemia, like HB-EGF, are promising therapeutic agents for the treatment of NEC.

  6. Ketogenesis contributes to intestinal cell differentiation.

    Science.gov (United States)

    Wang, Qingding; Zhou, Yuning; Rychahou, Piotr; Fan, Teresa W-M; Lane, Andrew N; Weiss, Heidi L; Evers, B Mark

    2017-03-01

    The intestinal epithelium undergoes a continual process of proliferation, differentiation and apoptosis. Previously, we have shown that the PI3K/Akt/mTOR pathway has a critical role in intestinal homeostasis. However, the downstream targets mediating the effects of mTOR in intestinal cells are not known. Here, we show that the ketone body β-hydroxybutyrate (βHB), an endogenous inhibitor of histone deacetylases (HDACs) induces intestinal cell differentiation as noted by the increased expression of differentiation markers (Mucin2 (MUC2), lysozyme, IAP, sucrase-isomaltase, KRT20, villin, Caudal-related homeobox transcription factor 2 (CDX2) and p21 Waf1 ). Conversely, knockdown of the ketogenic mitochondrial enzyme hydroxymethylglutaryl CoA synthase 2 (HMGCS2) attenuated spontaneous differentiation in the human colon cancer cell line Caco-2. Overexpression of HMGCS2, which we found is localized specifically in the more differentiated portions of the intestinal mucosa, increased the expression of CDX2, thus further suggesting the contributory role of HMGCS2 in intestinal differentiation. In addition, mice fed a ketogenic diet demonstrated increased differentiation of intestinal cells as noted by an increase in the enterocyte, goblet and Paneth cell lineages. Moreover, we showed that either knockdown of mTOR or inhibition of mTORC1 with rapamycin increases the expression of HMGCS2 in intestinal cells in vitro and in vivo, suggesting a possible cross-talk between mTOR and HMGCS2/βHB signaling in intestinal cells. In contrast, treatment of intestinal cells with βHB or feeding mice with a ketogenic diet inhibits mTOR signaling in intestinal cells. Together, we provide evidence showing that HMGCS2/βHB contributes to intestinal cell differentiation. Our results suggest that mTOR acts cooperatively with HMGCS2/βHB to maintain intestinal homeostasis.

  7. Gramsci y el proceso hegemónico educativo

    Directory of Open Access Journals (Sweden)

    Guillermo Miranda-Camacho

    2006-06-01

    Full Text Available El presente ensayo es una aproximación hermenéutica a uno de los núcleos centrales del pensamiento de Antonio Gramsci: la construcción del proceso hegemónico educativo y se destacan la actualidad y vigencia de su pensamiento. Para realizar esta tarea de analizar sus aportaciones, en un primer momento se hace una exploración de la interrelación del concepto de sociedad civil y su interacción dialéctica con el Estado (sociedad política. En un segundo momento se exploran las complejas, poderosas y sutiles formas que asume la hegemonía política y cultural promovida por la clase dirigente, desde el Estado, para consolidar un consenso ideológico en torno a su proyecto hegemónico. En un tercer momento, se exploran algunas dimensiones relativas a la participación directa del Estado en la educación, desde la perspectiva de los procesos que explican la vinculación histórica de lo político y lo educativo. Para comprender este proceso, se retoma el planteamiento gramsciano relativo a la hegemonía que se instaura en la sociedad civil en el marco de la construcción de una unidad social-cultural, analizando el concepto de intelectual orgánico y su papel en la configuración de la hegemonía social. La cuarta parte comprende un análisis de la vinculación histórica Estado-educación, desde la óptica de la articulación orgánica entre la base estructural y la superestructura ideológica, y, por ende, de la construcción de un sistema ideológico. Finalmente, se realiza una aproximación a la visión gramsciana de la vinculación educación-hegemonía, se destaca su significación y su vigencia para el análisis del papel de la política educativa como proceso hegemónico en la sociedad civil.

  8. VENEZUELA EN EL PROCESO DE INCORPORACIÓN AL MERCOSUR

    OpenAIRE

    Dani José Villalobos Soto; Enio Enrique Ortiz Valenzuela

    2012-01-01

    Diversos han sido los esquemas de integración que han experimentado en sus prácticas los países de Latinoamérica, en su lucha por lograr una concentración de esfuerzos frentes a las vicisitudes en aras de alcanzar intereses comunes para la región. Esta investigación enfoca al MERCOSUR como un proceso de integración que busca la conformación de un mercado común por medio de la eliminación de barreras arancelarias y para arancelarias. En ese sentido el presente estudio considera la participació...

  9. SISTEMA SCADA PARA EL PROCESO DE PASTEURIZACION DE JUGOS

    Directory of Open Access Journals (Sweden)

    Juan de Dios Contreras Cáceres

    2014-06-01

    Full Text Available La finalidad de este artículo es dar a conocer el proyecto desarrollado para diseñar e implementar un sistema SCADA (Supervisory Control And Data Adquisition aplicado al proceso de pasteurización de jugos. Se siguieron las etapas de diseño, partiendo de la elaboración del esquemático Layout, la programación del PLC, los drivers de comunicación y el diseño del software SCADA para una planta de jugos.

  10. La informalidad en los procesos identitarios de migrantes andinos

    OpenAIRE

    Macchiavello Lizárraga, Manuel Moisés

    2012-01-01

    La situación de migración abarca muchas variantes en el accionar cotidiano que el extranjero debe apropiar para desenvolverse en la sociedad mayor. Este proceso lleva consigo una negociación cultural que implica, por lo menos, ceder determinados parámetros habituales y ganar otros. El resultado: una sociedad que propone determinados aspectos pero que, además, acepta algunos otros que le eran anteriormente ajenos. Ante esta situación, el cúmulo migrante busca también elaborar espacio...

  11. LA SALUD EN EL PROCESO DE DESCENTRALIZACION TERRITORIAL EN VENEZUELA

    Directory of Open Access Journals (Sweden)

    Maritza Avila Urdaneta

    2001-07-01

    Full Text Available La estrategia de la descentralización del Estado se inicia con la aprobación de la Ley de Descentralización, Delimitación y Transferencia de Competencias del Poder Público (LOD en diciembre de 1989. El propósito de la descentralización es aumentar la capacidad de respuesta eficiente del sistema de servicios a los problemas de salud a la población entre los diferentes niveles de poder central, estadal y municipal, así como brindarle una mayor participación a las comunidades en su solución. En Venezuela las instituciones que prestan servicios de salud son numerosas, en su mayoría independientes y ausentes de una coordinación efectiva por parte del Ministerio de Sanidad y Asistencia Social (MSAS, ente creado en 1936 con mayor injerencia en los asuntos relativos a la salud. El MSAS se orienta hacia una política de centralización normativa – procedimental y desconcentración programática que consiste en la transferencia de las funciones administrativas, requeridas para el desarrollo de los programas, a los órganos regionales del Sistema Nacional de Salud. Destaca que el MSAS delimitará a las comunidades territorial, demográfica y técnicamente, en función del establecimiento de atención integral a la salud que le preste sus servicios. Este trabajo tiene como objetivo evaluar el proceso de descentralización de la salud, tomando en cuenta la actual coyuntura sociopolítica y económica en el marco de la nueva Constitución Bolivariana (1999. La muestra está constituida por los Estados Monagas, Carabobo, Aragua, Falcón y Zulia. Los resultados se concretan en el aumento de la productividad y calidad de los servicios de atención médica; simplificación de los procesos administrativos y el fortalecimiento de la democracia, al contar con una comunidad involucrada y satisfecha con el servicio de salud. Se concluye que el proceso de descentralización municipal ha sido frenado por el Gobierno central en los Estados Monagas y

  12. Afrontar el proceso de duelo To deal with grief

    OpenAIRE

    Mª Trinidad Pérez Vallejo

    2008-01-01

    Ana, con su testimonio y con su vida nos enseña como afrontar los procesos de duelo. La muerte de su esposo se produce en febrero de 2005, este suceso fue probablemente la experiencia más difícil e importante que ha pasado durante sus 74 años de vida. Ana cuidó a su esposo durante la enfermedad con celo, dedicación y sobre todo con mucho amor. Ahora nos cuenta su experiencia para que pueda servir a aliviar a todas aquellas personas que se hallan en una situación semejante, a la vez, que rinde...

  13. Procesos inflamatorios y tratamiento nutricional específico

    OpenAIRE

    López Parra, Andrea

    2014-01-01

    RESUMEN: INTRODUCCIÓN: La inflamación es una respuesta normal del organismo ante ciertos estímulos. Sin embargo, si esta es excesiva o inadecuada, puede dar lugar a distintas patologías. Para el tratamiento y prevención de estas, tanto desde el punto de vista médico como fisioterapéutico, es importante tener una visión holística del problema. En este punto el soporte nutricional es de gran importancia OBJETIVOS: Relacionar la nutrición con los procesos inflamatorios que se llevan a cabo en...

  14. Modelo de aplicaciones con procesos concurrentes y distribuidos

    OpenAIRE

    Giulianelli, Daniel Alberto; Rodríguez, Rocío Andrea; Vera, Pablo Martín

    2006-01-01

    En este paper se presenta un nuevo diagrama al cual hemos denominado DEA "Diagrama de Estados Activo". El mismo permite modelar todos los aspectos de las aplicaciones con procesos concurrentes y distribuidos. Como punto de partida se evaluaron los distintos modelos de UML 2.0 y viendo que ninguno de ellos se adaptaba por completo a las necesidades presentadas, se elabora éste modelo que toma las características de algunos diagramas de UML y agrega elementos necesarios para este tipo de aplica...

  15. Modelos de aplicaciones con procesos concurrentes y distribuidos

    OpenAIRE

    Giulianelli, Daniel Alberto; Rodríguez, Rocío Andrea; Vera, Pablo Martín

    2007-01-01

    En este paper se presenta u nuevo diagrama al cual hemos denominado DEA “Diagrama de Estados Activos”. El mismo permite modelar todos los aspectos de las aplicaciones con procesos concurrentes y distribuidos. Como punto de partida se evaluaron los distintos modelos de UML 2.0 y viendo que ninguno de ellos se adaptaba por completo a las necesidades presentadas, se elabora éste modelo que toma las características de algunos diagramas de UML y agrega elementos necesarios para este tipo de aplica...

  16. Epidermal Growth Factor and Intestinal Barrier Function

    Directory of Open Access Journals (Sweden)

    Xiaopeng Tang

    2016-01-01

    Full Text Available Epidermal growth factor (EGF is a 53-amino acid peptide that plays an important role in regulating cell growth, survival, migration, apoptosis, proliferation, and differentiation. In addition, EGF has been established to be an effective intestinal regulator helping to protect intestinal barrier integrity, which was essential for the absorption of nutrients and health in humans and animals. Several researches have demonstrated that EGF via binding to the EGF receptor and subsequent activation of Ras/MAPK, PI3K/AKT, PLC-γ/PKC, and STATS signal pathways regulates intestinal barrier function. In this review, the relationship between epidermal growth factor and intestinal development and intestinal barrier is described, to provide a better understanding of the effects of EGF on intestine development and health.

  17. Intestinal epithelium in inflammatory bowel disease

    Directory of Open Access Journals (Sweden)

    Mehmet eCoskun

    2014-08-01

    Full Text Available The intestinal epithelium has a strategic position as a protective physical barrier to luminal microbiota and actively contributes to the mucosal immune system. This barrier is mainly formed by a monolayer of specialized intestinal epithelial cells (IECs that are crucial in maintaining intestinal homeostasis. Therefore, dysregulation within the epithelial layer can increase intestinal permeability, lead to abnormalities in interactions between IECs and immune cells in underlying lamina propria, and disturb the intestinal immune homeostasis, all of which are linked to the clinical disease course of inflammatory bowel disease (IBD. Understanding the role of the intestinal epithelium in IBD pathogenesis might contribute to an improved knowledge of the inflammatory processes and the identification of potential therapeutic targets.

  18. Conceptualización de un Nodo Virtual de Procesos

    Directory of Open Access Journals (Sweden)

    Yoan Martínez Márquez

    2010-07-01

    Full Text Available Tradicionalmente en la carrera de ingeniería Automática, los contenidos teóricos de las diferentes asignaturas son impartidos por los docentes en clase pero esto no garantiza que los estudiantes adquieran las habilidades para hacer frente a los problemas reales. En la industria constituye una limitante el hecho de que cuando se desean realizar cambios en la estrategia de control, con vistas a entregar más y mejores productos, rápido y con un coste menor que sus competidores, no es posible probarlos en línea por las graves consecuencias que podría acarrear cualquier error en el diseño o implementación. Este proyecto se basa en la realización de un Nodo Virtual en el cual se implementan los modelos de distintos procesos, agrupados por tipos que dan la posibilidad de realizar simulaciones con los mismos o probar aplicaciones en tiempo real. Palabras claves: Control Automático, Nodos Virtuales, Procesos Industriales, Simulación.

  19. La muerte como proceso: una perspectiva antropológica

    Directory of Open Access Journals (Sweden)

    Bárbara Martínez

    2013-09-01

    Full Text Available Este artículo, desde una perspectiva antropológica, combina recientes aproximaciones que cuestionan la homología entre muerte y deceso biológico, con la tradición de estudios que revisan los rituales de muerte en el área geográfica andina. En particular, examina cómo se produce en El Cajón, Catamarca, noroeste argentino, la incorporación de un fallecido al esquema cosmológico, y cómo la muerte, que es un puntapié inicial para ello ocurra, no es meramente un evento biológico sino también un proceso social de gran dinamismo. A partir del trabajo de campo etnográfico, y tomando como herramientas metodológicas entrevistas abiertas de sesiones múltiples y observación participante, presenta una propuesta analítica que procura superar la homología entre muerte y deceso biológico, sugiriendo una noción que incluye la dimensión orgánica, pero también la social: el proceso de la muerte.

  20. Las superestructuras textuales en los procesos pedagógicos

    Directory of Open Access Journals (Sweden)

    Pardo Abril Neyla Graciela

    1992-06-01

    Full Text Available

    El propósito de este documento es presentar e ilustrar algunas consideraciones tendientes a posibilitar una metodología que se acerque de manera más funcional al desarrollo integral de las habilidades comunicativas, a partir de un marco teórico que aproxime a la descripción, explicación y predicción de los procesos de la producción y comprensión discursiva, teniendo en cuenta las más importantes contribuciones que en este sentido han elaborado la lingüística de texto, la sicología cognoscitiva y la cibernética, en particular, las digresiones en torno a la inteligencia artificial, desde donde se señala la importancia que tienen los procesos y categorías cognoscitivas en la comprensión y producción de discursos.

  1. La acreditacion como proceso dinamizador hacia la calidad

    Directory of Open Access Journals (Sweden)

    Belén Boville Luca de Tena

    2006-01-01

    Full Text Available Con metodología de estudio de caso se aborda la acreditación de un centro de Educación Superior mexicano, la Unidad Académica Multidisciplinaria de Comercio y Administración Victoria de la Universidad Autónoma de Tamaulipas. Mediante el estudio del proceso de evaluación se trata de descubrir cómo ha generado el dinamismo que permite una mejora sustancial de la calidad. Los hallazgos ponen de manifiesto un modelo de gestión que privilegia liderazgo compartido, planeación estratégica, autoevaluación y trabajo en equipo en torno a una visión común. Se identifica una planta docente profesionalizada y programas de estudio con enfoque integral, complementado con actividades de investigación, cultura y deporte. Comprometidos con un proceso de mejora contínua, la consolidación de metas a corto y largo plazo está íntimamente relacionada con el sentido de pertenencia de sus miembros a esa organización. La corresponsabilidad ante el éxito o el fracaso es una característica clave en el éxito de esta comunidad educativa.

  2. El desarrollo de la marcha infantil como proceso de aprendizaje

    Directory of Open Access Journals (Sweden)

    Patricia Martín Casas

    2014-06-01

    Full Text Available El desarrollo de la marcha infantil es un proceso especialmente complejo en que el intervienen factores motores, perceptivos y cognitivos. Desde el nacimiento, el niño integra la información recibida y realiza un progresivo control cortical sobre los patrones neuromotores innatos para desarrollar diferentes formas de locomoción hasta la marcha independiente. Estas ideas no son novedosas pero se están revisando en la actualidad y han motivado numerosos cambios en el estudio del desarrollo infantil. La consideración de la adquisición de la marcha como un aprendizaje en situaciones de constante cambio permite comprender la marcha como acción, cuya realización implica la adquisición de nuevas capacidades de interacción y conocimientos. En este trabajo se exponen los principales conocimientos acerca de este proceso de aprendizaje y se propone destacar las alteraciones de la marcha como indicadores de dificultades en el desarrollo, que requieren una valoración y un abordaje terapéutico interdisciplinares.

  3. Cinnamon polyphenols regulate multiple metabolic pathways involved in intestinal lipid metabolism of primary small intestinal enterocytes

    Science.gov (United States)

    Increasing evidence suggests that dietary factors may affect the expression of multiple genes and signaling pathways including those that regulate intestinal lipoprotein metabolism. The small intestine is actively involved in the regulation of dietary lipid absorption, intracellular transport and me...

  4. Propuesta para evaluar la capacidad de procesos de manufactura multivariados

    Directory of Open Access Journals (Sweden)

    Manuel Alberto Rodriguez Medina

    2014-08-01

    Full Text Available Los productos manufacturados hoy en día poseen varias características de calidad que son importantes para el cliente y cuando no están correlacionadas, se usan varios índices de capacidad, tales como el Cp, Cpk y Cpm para evaluar la habilidad que tiene el proceso de producir productos de calidad. Para el caso contrario, se encontró en la revisión de literatura, índices de capacidad propuestos para medir la capacidad de un proceso cuando las características de calidad están correlacionadas. La mayoría de las propuestas coinciden en que debe definirse una región de especificación que represente lo que el cliente desea y otra región de variación del proceso que muestre el desempeño que tiene el proceso. Adicionalmente, como resultados de la revisión anterior, se observa que los autores difieren en la forma de definir ambas regiones, oportunidad que se aprovecha para presentar una nueva propuesta, mediante la cual se definen de una manera confiable ambas regiones y que al compararlas se obtienen un par de índices de capacidad multivariados CpM y CpkM, que son extensiones de los índices univariados Cp y Cpk. Por último, se utilizan los datos de un proceso, los cuales se pueden modelar por medio de una distribución normal bivariada para calcular los índices de capacidad propuestos en este trabajo, posteriormente se comparan con el valor de otros índices de capacidad similares, propuestos por otros autores, obteniéndose un desempeño por sobre otros índices de la literatura consultada. The manufactured products have several quality characteristics that are important for the customer. When the quality characteristics are not correlated, using several indices, such as Cp, Cpk and Cpm to assess the ability of the process to produce quality products. For the opposite case was found in the literature review, proposed capability indices to measure the ability of a process when the quality characteristics are correlated. Most proposals

  5. The effect of gastric inhibitory polypeptide on intestinal glucose absorption and intestinal motility in mice

    Energy Technology Data Exchange (ETDEWEB)

    Ogawa, Eiichi [Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University (Japan); Hosokawa, Masaya [Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University (Japan); Faculty of Human Sciences, Tezukayama Gakuin University, Osaka (Japan); Harada, Norio; Yamane, Shunsuke; Hamasaki, Akihiro; Toyoda, Kentaro; Fujimoto, Shimpei; Fujita, Yoshihito; Fukuda, Kazuhito [Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University (Japan); Tsukiyama, Katsushi; Yamada, Yuichiro [Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University (Japan); Department of Internal Medicine, Division of Endocrinology, Diabetes and Geriatric Medicine, Akita University School of Medicine, Akita (Japan); Seino, Yutaka [Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University (Japan); Kansai Electric Power Hospital, Osaka (Japan); Inagaki, Nobuya, E-mail: inagaki@metab.kuhp.kyoto-u.ac.jp [Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University (Japan); CREST of Japan Science and Technology Cooperation (JST), Kyoto (Japan)

    2011-01-07

    Research highlights: {yields} Exogenous GIP inhibits intestinal motility through a somatostatin-mediated pathway. {yields} Exogenous GIP inhibits intestinal glucose absorption by reducing intestinal motility. {yields} The GIP-receptor-mediated action in intestine does not involve in GLP-1-mediated pathway. -- Abstract: Gastric inhibitory polypeptide (GIP) is released from the small intestine upon meal ingestion and increases insulin secretion from pancreatic {beta} cells. Although the GIP receptor is known to be expressed in small intestine, the effects of GIP in small intestine are not fully understood. This study was designed to clarify the effect of GIP on intestinal glucose absorption and intestinal motility. Intestinal glucose absorption in vivo was measured by single-pass perfusion method. Incorporation of [{sup 14}C]-glucose into everted jejunal rings in vitro was used to evaluate the effect of GIP on sodium-glucose co-transporter (SGLT). Motility of small intestine was measured by intestinal transit after oral administration of a non-absorbed marker. Intraperitoneal administration of GIP inhibited glucose absorption in wild-type mice in a concentration-dependent manner, showing maximum decrease at the dosage of 50 nmol/kg body weight. In glucagon-like-peptide-1 (GLP-1) receptor-deficient mice, GIP inhibited glucose absorption as in wild-type mice. In vitro examination of [{sup 14}C]-glucose uptake revealed that 100 nM GIP did not change SGLT-dependent glucose uptake in wild-type mice. After intraperitoneal administration of GIP (50 nmol/kg body weight), small intestinal transit was inhibited to 40% in both wild-type and GLP-1 receptor-deficient mice. Furthermore, a somatostatin receptor antagonist, cyclosomatostatin, reduced the inhibitory effect of GIP on both intestinal transit and glucose absorption in wild-type mice. These results demonstrate that exogenous GIP inhibits intestinal glucose absorption by reducing intestinal motility through a somatostatin

  6. The effect of gastric inhibitory polypeptide on intestinal glucose absorption and intestinal motility in mice

    International Nuclear Information System (INIS)

    Ogawa, Eiichi; Hosokawa, Masaya; Harada, Norio; Yamane, Shunsuke; Hamasaki, Akihiro; Toyoda, Kentaro; Fujimoto, Shimpei; Fujita, Yoshihito; Fukuda, Kazuhito; Tsukiyama, Katsushi; Yamada, Yuichiro; Seino, Yutaka; Inagaki, Nobuya

    2011-01-01

    Research highlights: → Exogenous GIP inhibits intestinal motility through a somatostatin-mediated pathway. → Exogenous GIP inhibits intestinal glucose absorption by reducing intestinal motility. → The GIP-receptor-mediated action in intestine does not involve in GLP-1-mediated pathway. -- Abstract: Gastric inhibitory polypeptide (GIP) is released from the small intestine upon meal ingestion and increases insulin secretion from pancreatic β cells. Although the GIP receptor is known to be expressed in small intestine, the effects of GIP in small intestine are not fully understood. This study was designed to clarify the effect of GIP on intestinal glucose absorption and intestinal motility. Intestinal glucose absorption in vivo was measured by single-pass perfusion method. Incorporation of [ 14 C]-glucose into everted jejunal rings in vitro was used to evaluate the effect of GIP on sodium-glucose co-transporter (SGLT). Motility of small intestine was measured by intestinal transit after oral administration of a non-absorbed marker. Intraperitoneal administration of GIP inhibited glucose absorption in wild-type mice in a concentration-dependent manner, showing maximum decrease at the dosage of 50 nmol/kg body weight. In glucagon-like-peptide-1 (GLP-1) receptor-deficient mice, GIP inhibited glucose absorption as in wild-type mice. In vitro examination of [ 14 C]-glucose uptake revealed that 100 nM GIP did not change SGLT-dependent glucose uptake in wild-type mice. After intraperitoneal administration of GIP (50 nmol/kg body weight), small intestinal transit was inhibited to 40% in both wild-type and GLP-1 receptor-deficient mice. Furthermore, a somatostatin receptor antagonist, cyclosomatostatin, reduced the inhibitory effect of GIP on both intestinal transit and glucose absorption in wild-type mice. These results demonstrate that exogenous GIP inhibits intestinal glucose absorption by reducing intestinal motility through a somatostatin-mediated pathway rather

  7. Differentiated thyroid carcinoma and intestinal polyposis syndromes.

    Science.gov (United States)

    Triggiani, Vincenzo; Angelo Giagulli, Vito; Tafaro, Angela; Resta, Francesco; Sabba, Carlo; Licchelli, Brunella; Guastamacchia, Edoardo

    2012-12-01

    Familial Adenomatous Polyposis, Cowden's Syndrome, and Peutz-Jeghers Syndrome are well known as Intestinal Polyposis Syndromes, inherited conditions characterized by the development of polyps of the gastro-intestinal tract in association with extra-intestinal manifestations, in particular malignant tumors at different sites. Thyroid carcinoma is sometimes a part of the clinical picture of these syndromes. The aim of this paper is to review the literature dealing with the association between differentiated thyroid carcinomas and Intestinal Polyposis Syndromes in order to point out peculiar aspects, providing suggestions for the screening and the management of thyroid tumors in these patients.

  8. Sonographic diagnosis of intestinal polyps in children.

    Science.gov (United States)

    Parra, Dimitri A; Navarro, Oscar M

    2008-06-01

    Although colonoscopy is the modality of choice for the diagnosis of intestinal polyps, sonography may be the first diagnostic modality in the evaluation of children with this pathology. Graded compression sonography of the small and large bowel may be useful in diagnosing intestinal polyps. A specific diagnosis is possible in many cases as most polyps have a characteristic appearance. Although sonography is not intended to replace endoscopy in the diagnostic work-up of intestinal polyps, it is important for radiologists to be aware of this appearance as they can be the first in making the diagnosis of intestinal polyps using sonography.

  9. Intestinal absorption of fluorescently labeled nanoparticles.

    Science.gov (United States)

    Simovic, Spomenka; Song, Yunmei; Nann, Thomas; Desai, Tejal A

    2015-07-01

    Characterization of intestinal absorption of nanoparticles is critical in the design of noninvasive anticancer, protein-based, and gene nanoparticle-based therapeutics. Here we demonstrate a general approach for the characterization of the intestinal absorption of nanoparticles and for understanding the mechanisms active in their processing within healthy intestinal cells. It is generally accepted that the cellular processing represents a major drawback of current nanoparticle-based therapeutic systems. In particular, endolysosomal trafficking causes degradation of therapeutic molecules such as proteins, lipids, acid-sensitive anticancer drugs, and genes. To date, investigations into nanoparticle processing within intestinal cells have studied mass transport through Caco-2 cells or everted rat intestinal sac models. We developed an approach to visualize directly the mechanisms of nanoparticle processing within intestinal tissue. These results clearly identify a mechanism by which healthy intestinal cells process nanoparticles and point to the possible use of this approach in the design of noninvasive nanoparticle-based therapies. Advances in nanomedicine have resulted in the development of new therapies for various diseases. Intestinal route of administration remains the easiest and most natural. The authors here designed experiments to explore and characterize the process of nanoparticle transport across the intestinal tissue. In so doing, further insights were gained for future drug design. Copyright © 2015 Elsevier Inc. All rights reserved.

  10. Bile acids in regulation of intestinal physiology.

    LENUS (Irish Health Repository)

    Keating, Niamh

    2009-10-01

    In addition to their roles in facilitating lipid digestion and absorption, bile acids are recognized as important regulators of intestinal function. Exposure to bile acids can dramatically influence intestinal transport and barrier properties; in recent years, they have also become appreciated as important factors in regulating cell growth and survival. Indeed, few cells reside within the intestinal mucosa that are not altered to some degree by exposure to bile acids. The past decade saw great advances in the knowledge of how bile acids exert their actions at the cellular and molecular levels. In this review, we summarize the current understanding of the role of bile acids in regulation of intestinal physiology.

  11. Intestinal myiasis caused by Muscina stabulans

    Directory of Open Access Journals (Sweden)

    Shivekar S

    2008-01-01

    Full Text Available Intestinal maggots were isolated from a patient, who had reported to the Department of General Medicine of Sri Manakula Vinayagar Medical College, Puducherry, in southern India with complaints of abdominal distress, bloating of abdomen and intestinal hurry following a meal. He was diagnosed as a case of intestinal myiasis. Maggots obtained from his stool were identified to be Muscina stabulans based on characteristic patterns of posterior spiracles. He was treated with purgatives and albendazole. This intestinal myiasis case caused by M. stabulans is reported here because of its rare occurrence and the need to establish a correct diagnosis.

  12. Ischemia-reperfusion and neonatal intestinal injury.

    Science.gov (United States)

    Young, Christopher M; Kingma, Sandra D K; Neu, Josef

    2011-02-01

    We review research relating ischemia/reperfusion to injury in the neonatal intestine. Epidemiologic evidence suggests that the most common form of necrotizing enterocolitis is not triggered by a primary hypoxic-ischemic event. Its late occurrence, lack of preceding ischemic events, and evidence for microbial and inflammatory processes preclude a major role for primary hypoxic ischemia as the sentinel pathogenic event. However, term infants, especially those with congenital heart disease who have development of intestinal necrosis, and those preterm infants with spontaneous intestinal perforations, are more likely to have intestinal ischemia as a primary component of their disease pathogenesis. Copyright © 2011 Mosby, Inc. All rights reserved.

  13. Effects of digested onion extracts on intestinal gene expression: an interspecies comparison using different intestine models

    NARCIS (Netherlands)

    Hulst, M.M.; Meulen, van der J.; Hoekman, A.J.W.; Smits, M.A.

    2016-01-01

    Applicability of in vitro (human Caco-2 cells) and ex vivo intestine models (rat precision cut intestine slices and the pig in-situ small intestinal segment perfusion (SISP) technique) to study the effect of food compounds. In vitro digested yellow (YOd) and white onion extracts (WOd) were used as

  14. Intestinal Microbiota Signatures Associated With Histological Liver Steatosis in Pediatric-Onset Intestinal Failure

    NARCIS (Netherlands)

    Korpela, K.; Mutanen, A.; Salonen, A.; Savilahti, E.; Vos, de W.M.; Pakarinen, M.P.

    2017-01-01

    BACKGROUND: Intestinal failure (IF)-associated liver disease (IFALD) is the major cause of mortality in IF. The link between intestinal microbiota and IFALD is unclear. METHODS: We compared intestinal microbiota of patients with IF (n = 23) with healthy controls (n = 58) using culture-independent

  15. Fortalecimiento de la calidad en procesos de software y procesos de gestión para la mejora de las sociedades del conocimiento

    OpenAIRE

    Esponda, Silvia; Pasini, Ariel C.; Boracchia, Marcos; Calabrese, Julieta; Muñoz, Rocio; Preisegger, Santiago; Estévez, Elsa Clara; Fillottrani, Pablo Rubén; Pesado, Patricia Mabel

    2017-01-01

    El III-LIDI (Instituto de Investigación en Informática LIDI), en el marco de diferentes proyectos acreditados, posee un grupo dedicado a la investigación y desarrollo relacionado con la mejora de los procesos de gestión y el aseguramiento de la calidad en procesos de gestión y productos de software. Los proyectos abarcan: - Mejora de los servicios de gobierno digital: en unidades académicas de nivel universitario y en organismos públicos de gobierno - Mejora de procesos: en el ámbito un...

  16. Inflammatory mediators and intestinal injury.

    Science.gov (United States)

    Caplan, M S; MacKendrick, W

    1994-06-01

    Although the causes of necrotizing enterocolitis (NEC) are not well understood, there is compelling evidence to suggest that the inflammatory mediators play an important role in the pathophysiology of the disease. This article examines the role of platelet-activating factor (PAF) and other mediators on the development of NEC, and attempts to explain the association of the putative NEC risk factors with altered mediator production and subsequent intestinal injury. The authors hypothesize that PAF is a key mediator in the final common pathway leading to NEC.

  17. Intestinal Lymphangiectasia Secondary to Neuroblastoma

    Directory of Open Access Journals (Sweden)

    RM Reifen

    1994-01-01

    Full Text Available An eight month-old infant presented with a 10-day history of vomiting and diarrhea, and a one-week history of swelling of the lower extremities. Laboratory evaluations revealed hypoproteinemia and lymphocytopenia due to protein-losing enteropathy. Peroral small bowel biopsy showed intestinal lymphangiectasia. Subsequent onset of unexplained ecchymosis and obstructive jaundice resulted in additional studies which revealed an omental neuroblastoma as the underlying etiology of the infant’s symptoms. This report emphasizes the importance of considering secondary, obstructive causes for lymphangiectasia and protein-losing enteropathy.

  18. LA MERCADOTECNIA MUSICAL EN EL PROCESO DE APRENDIZAJE DE UNIVERSITARIOS

    Directory of Open Access Journals (Sweden)

    Eduardo Muñoz Bautista

    2017-10-01

    Full Text Available Una de las instituciones educativas nivel superior más representativas de este estado es la (UAEH la misma que sostiene ser la institución de enseñanza más antigua de esta entidad federativa. El plantel nació con el estado; en sus distintas etapas de desarrollo se reflejan las correspondientes épocas de la historia hidalguense. Así mismo establece que durante 48 años de vida institucional, la Universidad ha vivido múltiples e importantes cambios caracterizados por un rápido crecimiento y expansión de cada una de sus funciones sustantivas. El presente artículo presenta los resultados de la investigación Perspectiva de aceptación del Marketing musical en una Universidad El Caso: Universidad Autónoma del Estado de Hidalgo (UAEH Instituto de Ciencias Económico Administrativas (ICEA, encontrándose como antecedentes que las instituciones de educación superior tienen como objetivo formar competencias en los individuos de acuerdo a su área del conocimiento, de tal forma que desarrolle armónicamente las facultades cognitivas, afectivas y psicomotoras, a fin de propiciar continuamente su mejoramiento intelectual, físico, social, moral y cultural. El diseño de la investigación fue de corte cuantitativo, transversal, descriptivo y Correlacional, teniendo como Hipótesis: H1: Los alumnos tienen una Actitud positiva hacia la conducta al emplear marketing musical dentro del proceso enseñanza-aprendizaje. H2: Los alumnos tienen creencias subjetivas de manera positiva aplicables al marketing musical dentro del proceso enseñanza-aprendizaje. De acuerdo a los resultados obtenidos el notable la aceptación de reproducción de música por parte del estudiante dentro su formación académica sin embargo, la mayoría señala que no se les ha dado la oportunidad de incorporar la música dentro de sus actividades académicas así como en su proceso de aprendizaje dentro de su escuela, por tanto se propone a los directivos de la instituci

  19. EL PROFESOR COMO GESTOR DEL PROCESO ACADÉMICO

    Directory of Open Access Journals (Sweden)

    María Morella Colls Carrillo

    2013-03-01

    Full Text Available El presente estudio tiene como objetivo abordar los procesos de cambio que están ocurriendo en la educación superior, y el papel del profesor universitario como gestor del conocimiento en entorno del aprendizaje. En tal sentido, se analizan y discuten las percepciones de un grupo de profesores de la Universidad Nacional Experimental Simón Rodríguez en torno de las tecnologías de la información y de la comunicación (TICs y los cambios que genera su implementación en los procesos de enseñanza y del aprendizaje. El escenario es los cambios que se generan con la implementación de las tecnologías de la información y de la comunicación en los procesos de enseñanza aprendizaje. El resultado de esta investigación se traducirá en las interpretaciones conceptuales y teóricas que darán soporte a la conceptualización conforme a la nueva visión expresada en el marco legal que la fundamenta y en su pertinencia social. Como aporte se espera generar constructos teóricos sobre la actuación del profesor como gestor universitario.PALABRAS CLAVE: conocimiento; educación; comunicación; TICsTHE TEACHER AS AGENT OF THE ACADEMIC PROCESS  ABSTRACTThe present study has as objective to approach the processes of change that are happening in the superior education, and the university professor's paper as agent of the knowledge in environment of the learning. In such a sense, they are analyzed and the perceptions of a group of professors of the National Experimental University name after Simón Rodríguez in lathe of the information and of the communication technologies (ICT and the changes that generates their implementation in the teaching and learning processes. The scenario is the changes that are generated with the implementation of the technologies of the information and of the communication in the processes of teaching learning. The result of this investigation will be translated in the conceptual and theoretical interpretations that will give

  20. Prematurity reduces functional adaptation to intestinal resection in piglets

    DEFF Research Database (Denmark)

    Aunsholt, Lise; Thymann, Thomas; Qvist, Niels

    2015-01-01

    Background: Necrotizing enterocolitis and congenital gastrointestinal malformations in infants often require intestinal resection, with a subsequent risk of short bowel syndrome (SBS). We hypothesized that immediate intestinal adaptation following resection of the distal intestine with placement ...

  1. The Adaptive Response to Intestinal Oxidative Stress in Mammalian Hibernation

    National Research Council Canada - National Science Library

    Carey, Hannah V

    2006-01-01

    .... Specific Aim 2 examines consequences of intestinal oxidative stress during hibernation including seasonal changes in NF-kB activation in intestine, seasonal changes in the intestinal mucosal immune...

  2. Lymphoma Caused by Intestinal Microbiota

    Directory of Open Access Journals (Sweden)

    Mitsuko L. Yamamoto

    2014-09-01

    Full Text Available The intestinal microbiota and gut immune system must constantly communicate to maintain a balance between tolerance and activation: on the one hand, our immune system should protect us from pathogenic microbes and on the other hand, most of the millions of microbes in and on our body are innocuous symbionts and some can even be beneficial. Since there is such a close interaction between the immune system and the intestinal microbiota, it is not surprising that some lymphomas such as mucosal-associated lymphoid tissue (MALT lymphoma have been shown to be caused by the presence of certain bacteria. Animal models played an important role in establishing causation and mechanism of bacteria-induced MALT lymphoma. In this review we discuss different ways that animal models have been applied to establish a link between the gut microbiota and lymphoma and how animal models have helped to elucidate mechanisms of microbiota-induced lymphoma. While there are not a plethora of studies demonstrating a connection between microbiota and lymphoma development, we believe that animal models are a system which can be exploited in the future to enhance our understanding of causation and improve prognosis and treatment of lymphoma.

  3. Intestinal histoplasmosis in immunocompetent adults.

    Science.gov (United States)

    Zhu, Lin-Lin; Wang, Jin; Wang, Zi-Jing; Wang, Yi-Ping; Yang, Jin-Lin

    2016-04-21

    To present a retrospective analysis of clinical and endoscopic features of 4 cases of immunocompetent hosts with intestinal histoplasmosis (IH). Four immunocompetent adults were diagnosed with IH between October 2005 and March 2015 at West China Hospital of Sichuan University. Clinical and endoscopic characteristics were summarized and analyzed retrospectively. GMS (Gomori methenamine silver), PAS (periodic acid-Schiff) and Giemsa staining technique were used to confirm Histoplasma capsulatum(H. capsulatum). The symptoms, signs, endoscopic presentations, radiographic imaging, pathological stain results and follow-up are presented as tables and illustrations. The cases were male patients, ranging from 33 to 61 years old, and primarily presented with non-specific symptoms such as irregular fever, weight loss, abdominal pain and distention. Hepatosplenomegaly and lymphadenopathy were the most common signs. Endoscopic manifestations were localized or diffuse congestion, edema, ulcers, and polypoid nodules with central erosion involving the terminal ileum, ascending colon, transverse colon, descending colon, sigmoid colon and rectum, similar to intestinal tuberculosis, tumor, and inflammatory bowel disease. Numerous yeast-like pathogens testing positive for PAS and GMS stains but negative for Giemsa were detected in the cytoplasm of the histiocytes, which were highly suggestive of H. capsulatum. Immunocompetent individuals suffering from histoplasmosis are rarely reported. It is necessary that gastroenterologists and endoscopists consider histoplasmosis as a differential diagnosis, even in immunocompetent patients.

  4. Desarrollo de Simuladores para Procesos Industriales. Parte III (Colada continua

    Directory of Open Access Journals (Sweden)

    Ramírez, A.

    2006-06-01

    Full Text Available This work was written for illustrating the use of Monte Carlo methods and generating of random number in combination with the information of the simulation system for thermal behavior described previously in order to reproduce in a computer the solidification process of the steel and simulate the formation of structures of casting step by step.

    Este trabajo muestra el empleo de técnicas de métodos de Monte Carlo y generación de números aleatorios en combinación con datos obtenidos del sistema de simulación (SSCC para comportamiento térmico previamente descrito para la reproducción computacional del proceso de solidificación del acero y simular la formación de estructuras de colada paso a paso.

  5. El rendimiento diferido del proceso didáctico

    Directory of Open Access Journals (Sweden)

    Juan Bautista CODINA BAS

    2009-11-01

    Full Text Available El análisis input-output es un modelo de investigación utilizado en las ciencias económicas y que se viene aplicando en el campo didáctico con diversos objetivos; bien de carácter político-administrativo para ayudar a tomar decisiones adecuadas, bien con el deseo de optimizar el proceso didáctico, buscando la calidad y eficacia en la educación. En todos los estudios se trata de identificar cuáles son los pesos de los factores que influyen en el rendimiento de los estudiantes, o dicho de otra forma: ¿hasta qué punto las variaciones en los rendimientos son explicados por la variación en los recursos utilizados? En resumen, se trata de conocer si el resultado obtenido está en consonancia con los medios adoptados.

  6. EL PENSAMIENTO ESTRATÉGICO COMO UN PROCESO DE APRENDIZAJE

    Directory of Open Access Journals (Sweden)

    Alberto, Levy

    2012-06-01

    Full Text Available Partiendo de la noción central de que toda estrategia es siempre una teoría, necesariamente, toda estrategia está basada en conjeturas (especulaciones con respecto al desempeño esperado de un sistema en su entorno y, como tales, esas conjeturas deben ser expuestas a la posibilidad de ser refutadas con el propósito de elevar su efectividad y su eficiencia en lograr los objetivos que procura. Esta sucesión de conjeturas y refutaciones es el centro de la metodología de pensamiento estratégico como proceso de aprendizaje y, por lo tanto,como el impulso del Desarrollo Competitivo.

  7. Conceptualización del proceso de envejecimiento

    Directory of Open Access Journals (Sweden)

    María Guadalupe Zetina Lozano

    1999-01-01

    Full Text Available El estudio de las personas mayores requiere de la conceptualización a la que se han referido diversas disciplinas, independientemente de los diversos enfoques teóricos que cada una sostiene. Se realiza en este trabajo una revisión de las principales tesis utilizadas por las disciplinas demográfica, biológica, socioeconómica, sociocultural y psicológica, principalmente enfocada al desarrollo humano. De estos planteamientos teóricos surgen supuestos hipotéticos: las personas de la tercera edad deben ubicarse dentro de un proceso dinámico, por lo que se propone estudiarlas en sus diferentes edades. Los resultados también dependen directamente de la forma en que se haya vivido esas etapas. Para ser analizado integralmente este fenómeno, será observado a través de dimensiones interdisciplinarias y del entorno familiar.

  8. Proceso creativo y ready-made en la publicidad

    Directory of Open Access Journals (Sweden)

    João Anzanello Carrascoza

    2012-04-01

    Full Text Available La creación publicitaria es el resultado de una práctica de bricolaje llevada a cabo por un redactor y un director de arte – profesionales que actúan a dúo en las agencias de publicidad y que son los responsables de la elaboración de los mensajes publicitarios. En este proceso, estos profesionales echan mano de todo tipo de materiales culturales para crear las piezas que les son solicitadas. Ambos se valen sistemáticamente, como materia prima, de citaciones de imágenes y enunciados fundadores, interfiriendo en su significado, hecho que hace pensar en los ready-mades de Duchamp. Este artículo aporta una reflexión sobre el ready-made como método de creación en la publicidad y sus implicaciones en el mundo de los signos.

  9. PROCESO DE FORMACIÓN URBANA DE ORIHUELA (ALICANTE

    Directory of Open Access Journals (Sweden)

    Gregorio Canales Martínez

    1992-01-01

    Full Text Available La evolución urbana de Orihuela ha venido marcada por un progresivo desplaza- miento desde su primitiva ubicación de carácter defensivo en el Monte San Miguel hasta ir ocupando las tierras ribereñas del río Segura, cuyo cauce ha definido hasta fechas muy cercanas su desarrollo urbano. El estudio determina los elementos y circunstancias que han condicionado el proceso de formación urbana desde el siglo XIV hasta nuestros días y sus tendencias expansivas, a través del análisis de la documentación histórica disponi- ble, tanto gráfica como bibliográfica, ofreciendo así una síntesis de la evolución histórica de la ciudad.

  10. Alteraciones psicosociales en el proceso docente-educativo

    Directory of Open Access Journals (Sweden)

    Patricia María Herrera Santí

    2001-08-01

    Full Text Available Resumen Nuestra investigación estudió algunos de los factores psicosociales por los que está influido el proceso docente-educativo y las alteraciones de aprendizaje y conducta en educandos de enseñanza primaria. Conocimos sexo y edades más frecuentes en las que se afecta el proceso docente-educativo, establecimos relación entre el estilo de participación del niño y las alteraciones docentes, constatamos la influencia de crisis familiares no transitorias y el funcionamiento familiar, evaluamos igualmente el funcionamiento intelectual y las principales áreas de conflicto. Se encontró un predominio de los trastornos de conducta sobre los trastornos del aprendizaje, un funcionamiento intelectual dentro de límites normales, así como también una adecuada maduración neuromotriz; una alta incidencia de crisis familiares no transitorias, alteraciones en el clima familiar y un mal funcionamiento familiar.Summary We studied some of the psychosocial factors influencing on the teaching-educative process and the learning and behavioral alterations in primary school students. We knew the most frequent age and sex in which the teaching-educative process is affected, we established a relationship between the style of participation of the child and the teaching alterations, and evaluated the intellectual functioning and the main conflict areas. It was observed a predominance of the behavorial disorders over the learning disorders, an intellectual functioning within the normal limits, as well as an adequate neuromotor maturation, a high incidence of non-transitory family crises, alteration in the family atmosphere and a poor family functioning.

  11. El Proceso de Internacionalización de Empresas

    Directory of Open Access Journals (Sweden)

    Arnoldo Araya Leandro

    2013-01-01

    Full Text Available El fenómeno de la globalización insta a las empresas adesarrollar estrategias con el propósito de internacionalizarse,no obstante es una tarea compleja. En algunos casos, loque busca la internacionalización es la apertura de nuevosmercados, en otros es que los costos de producción sean másbajos y que haya una estructura eficiente de producción ydistribución. Dado lo anterior, el proceso de internacionalizaciónempresarial debe responder las siguientes preguntas:¿por qué se internacionaliza la empresa?, ¿cuál es el procesopara llevarlo a cabo?, ¿cómo se internacionaliza? y ¿dóndepuede localizar sus actividades en el exterior? (Galán, Galende,González, 2000. A partir de estos cuestionamientosla presente investigación bibliográfica tiene como objetivoprincipal mostrar el proceso que deben seguir las empresascon el fin de internacionalizarse.   ABSTRACT The globalization phenomenon pressures companies intothe complex undertaking of the development of strategies fortheir internationalization. Sometimes internationalizationseeks opening new markets, in other cases its goals are loweringproduction and distribution costs. As a result, any companyseeking to participate in an internationalization process mustanswer the following questions: Why do we want to go global?What’s the process that must be followed?How do you do it? Where are we going to operate? (Galan,Galende, Gonzalez, 2000. From these questions the currentliterature research shows the procedure to be followed bycompanies wishing to operate worldwide.

  12. ACCESIBILIDAD AL PROCESO EDUCATIVO EN EL ENTORNO UNIVERSITARIO

    Directory of Open Access Journals (Sweden)

    Martha Gross Martínez

    2016-01-01

    Full Text Available Resumen: Este artículo presenta los hallazgos de la investigación Accesibilidad en la permanencia de estudiantes con necesidades educativas asociadas o no a discapacidad, en una universidad pública de Costa Rica (2012-2014. El objetivo de dicho estudio consistió en analizar la accesibilidad desde la percepción estudiantil sobre las acciones, apoyos y servicios dentro de la vida universitaria, a partir de las diferentes dimensiones de la accesibilidad (espacio físico, información y proceso educativo y con ello aportar propuestas que permitan y dinamicen la inclusión en este nivel educativo. Este estudio se adscribe a la investigación cualitativa. La población participante se seleccionó considerando las necesidades de accesibilidad en el entorno universitario. Se expone de manera particular el análisis de los resultados sobre accesibilidad al proceso educativo en este contexto. Se realizó una revisión bibliográfica que permitiera la reflexión sobre el objeto de estudio, además, se llevó a cabo una encuesta en línea al estudiantado y la realización de grupos focales para la recolección de datos. Finalmente, se pone de manifiesto los logros y carencias que existen en materia de accesibilidad en el ámbito educativo, puntualizando aspectos vinculantes con el derecho a la educación y el compromiso institucional, ante los desafíos que esta población enfrenta en el quehacer de la vida estudiantil.

  13. Accesibilidad al proceso educativo en el entorno universitario

    Directory of Open Access Journals (Sweden)

    Gross Martínez, Martha

    2016-02-01

    Full Text Available Este artículo presenta los hallazgos de la investigación Accesibilidad en la permanencia de estudiantes con necesidades educativas asociadas o no a discapacidad, en una universidad pública de Costa Rica (2012-2014. El objetivo de dicho estudio consistió en analizar la accesibilidad desde la percepción estudiantil sobre las acciones, apoyos y servicios dentro de la vida universitaria, a partir de las diferentes dimensiones de la accesibilidad (espacio físico, información y proceso educativo y con ello aportar propuestas que permitan y dinamicen la inclusión en este nivel educativo. Este estudio se adscribe a la investigación cualitativa. La población participante se seleccionó considerando las necesidades de accesibilidad en el entorno universitario. Se expone de manera particular el análisis de los resultados sobre accesibilidad al proceso educativo en este contexto. Se realizó una revisión bibliográfica que permitiera la reflexión sobre el objeto de estudio, además, se llevó a cabo una encuesta en línea al estudiantado y la realización de grupos focales para la recolección de datos. Finalmente, se pone de manifiesto los logros y carencias que existen en materia de accesibilidad en el ámbito educativo, puntualizando aspectos vinculantes con el derecho a la educación y el compromiso institucional, ante los desafíos que esta población enfrenta en el quehacer de la vida estudiantil.

  14. Tres experimentos Modernos. El proceso de proyecto del edificio Positano

    Directory of Open Access Journals (Sweden)

    Juan Pablo Tuja

    2017-04-01

    Full Text Available El edificio Positano, proyectado durante la década de 1950 por el arquitecto Luis García Pardo, marca un hito en la arquitectura de la vivienda colectiva moderna en el Uruguay. Para concretar este edificio, el arquitecto -y promotor inmobiliario a la vez- desarrolló una serie de proyectos, identificándose tres proyectos completamente documentados. Esta serie posee un fuerte carácter moderno y experimental, el cual se expresa en la volumetría general, la implantación, en el desarrollo tipológico, el diseño estructural y el diseño de los cerramiento exteriores. El último proyecto, realizado en asociación con el joven arquitecto Adolfo Sommer Smith, comienza a construirse en 1959. La serie de proyectos, evidencia un creciente proceso de “abstracción”, tanto formal como conceptual. Lo cual conducirá por un lado a simplificar formas y reducir elementos, y por otro a diseñar dispositivos de mayor complejidad, capaces de resolver funciones diversas al mismo tiempo. A partir de la búsqueda y clasificación de documentación de época –planos, fotografías, artículos, entre otros–, el presente trabajo intentó ensayar una interpretación proyectual, exponiendo las principales preocupaciones y estrategias de los arquitectos. El ensayo buscó reconocer repeticiones, iteraciones, dudas y certezas de un proceso proyectual intenso, que transitó los bordes de la disciplina.

  15. Empoderamiento: Proceso, Nivel y Contexto Empowerment: Process, Level, and Context

    Directory of Open Access Journals (Sweden)

    Carmen Silva

    2004-11-01

    Full Text Available En este artículo se discute el fenómeno del empoderamiento y se analiza la distinción teórica entre proceso y resultado de empoderamiento (Zimmerman, 2000. A partir de las formulaciones de este autor y el aporte de una perspectiva interaccional (Bronfenbrenner, 1987, se sostiene que aquella diferenciación es poco viable en términos objetivos y absolutos o de esencia, pero sí útil, en términos analíticos, desde la percepción de la propia comunidad involucrada, que debe ser comprendida por el colaborador externo. También se propone establecer una diferencia entre contexto y nivel de empoderamiento, y analizar el contexto del fenómeno en los niveles individual, organizacional y comunitario del agregado social, lo que aporta claridad a su definición. De esta manera adquiere centralidad la concepción del empoderamiento como proceso en sucesivos contextos que benefician no sólo a los individuos sino que a los colectivos socialesA critical analysis of the concept of empowerment and the theoretical distinction between empowerment process and outcome (Zimmerman, 2000 are presented. Based on Zimmerman's conceptualisation, and the interaccional perspective (Bronfenbrenner, 1987, we argue that the distinction between empowerment process and outcome, though analytically useful (if based on the perception of the community itself from their own experience, which must be understood by professional agent is not always viable in absolute or objective terms. In addition, we suggest to distinguish between context and level of analyses in empowerment theory, and to analyze the context of the empowerment phenomenon at the individual, organizational and community level, which clarifies the definition of each of them. In sum, empowerment is conceived as a process within successive contexts that benefits not only individuals, but also different social aggregate kinds of groups

  16. Megacystis microcolon intestinal hypoperistalsis syndrome: a report ...

    African Journals Online (AJOL)

    The prognosis is poor and most patients die early because of sepsis or total parental nutrition-related complications. This report describes a new case of megacystis microcolon intestinal hypoperistalsis syndrome associated with meconium ileus, dilated stomach, and megaesophagus. Keywords: intestinal hypoperistalsis ...

  17. Intestinal cholesterol secretion: future clinical implications

    NARCIS (Netherlands)

    Jakulj, L.; Besseling, J.; Stroes, E. S. G.; Groen, A. K.

    2013-01-01

    Together with the liver, the intestine serves as a homeostatic organ in cholesterol metabolism. Recent evidence has substantiated the pivotal role of the intestine in reverse cholesterol transport (RCT). RCT is a fundamental antiatherogenic pathway, mediating the removal of cholesterol from tissues

  18. Intestinal cholesterol secretion : future clinical implications

    NARCIS (Netherlands)

    Jakulj, L.; Besseling, J.; Stroes, E. S. G.; Groen, A. K.

    2013-01-01

    Together with the liver, the intestine serves as a homeostatic organ in cholesterol metabolism. Recent evidence has substantiated the pivotal role of the intestine in reverse cholesterol transport (RCT). RCT is a fundamental antiatherogenic pathway, mediating the removal of cholesterol from tissues

  19. Alkaline Phosphatases From Camel Small Intestine | Fahmy ...

    African Journals Online (AJOL)

    Camel intestinal alkaline phosphatase have been purified and characterized. The purification was carried out by chromatography on DEAE-cellulose. Five intestinal alkaline phosphatase isoenzymes (IAP1 to IAP5) were obtained. IAP2 and IAP5 with the highest activity levels were purified to homogeneity by Sephacryl ...

  20. Megacystis microcolon intestinal hypoperistalsis syndrome: a report ...

    African Journals Online (AJOL)

    intestinal peristalsis. The prognosis is poor and most patients die early because of sepsis or total parental nutrition-related complications. This report describes a new case of megacystis microcolon intestinal hypoperistalsis syndrome associated with meconium ileus, dilated stomach, and megaesophagus. Ann Pediatr Surg.

  1. Is nonoperative management of adhesive intestinal obstruction ...

    African Journals Online (AJOL)

    Background: Nonoperative management of adhesive intestinal obstruction gives good results in adults but there are scant studies on its outcome in children. This study reports outcomes and experiences with nonoperative and operative management of adhesive intestinal obstruction in children in a resource-poor country.

  2. Laparoscopic Treatment of Intestinal Malrotation in Children

    NARCIS (Netherlands)

    Ooms, N.; Matthyssens, L.E.; Draaisma, J.M.T.; Blaauw, I. de; Wijnen, M.H.

    2016-01-01

    Purpose Intestinal malrotation is a congenital intestinal rotation anomaly, which can be treated by either laparotomy or laparoscopy. Our hypothesis is that laparoscopic treatment leads to less small bowel obstruction because of the fewer adhesions in comparison to laparotomy, without increasing the

  3. Species and prevalence determination of Human Intestinal ...

    African Journals Online (AJOL)

    Intestinal parasitic infections constitute a global health burden causing clinical morbidity. Parasitic protozoa and helminthes are responsible for some of the most devastating and prevalent diseases of human. The study was conducted to determine the prevalence of intestinal parasites among patients attending Federal ...

  4. Ectoparasites and intestinal helminths of speckled pigeon ...

    African Journals Online (AJOL)

    Ectoparasites and intestinal helminths of speckled pigeon ( Columba guinea Hartlaub and Finsch 1870) in Zaria, Nigeria. ... Science World Journal ... A total of 30 (20 males and 10 females) Speckled Pigeons trapped from the wild in Zaria and its environs, Nigeria, were examined for ectoparasites and intestinal helminths, ...

  5. Species and prevalence determination of Human Intestinal ...

    African Journals Online (AJOL)

    ADOWIE PERE

    ABSTRACT: Intestinal parasitic infections constitute a global health burden causing clinical morbidity. Parasitic protozoa and helminthes are responsible for some of the most devastating and prevalent diseases of human. The study was conducted to determine the prevalence of intestinal parasites among patients attending ...

  6. Intestinal radiation syndrome: sepsis and endotoxin

    International Nuclear Information System (INIS)

    Geraci, J.P.; Jackson, K.L.; Mariano, M.S.

    1985-01-01

    Rats were whole-body irradiated with 8-MeV cyclotron-produced neutrons and 137 Cs γ rays to study the role of enteric bacteria and endotoxin in the intestinal radiation syndrome. Decrease in intestinal weight was used as an index of radiation-induced breakdown of the mucosa. Neutron and γ-ray doses that were sublethal for intestinal death resulted in a dose-dependent decrease in intestinal weight, reaching minimal values 2 to 3 days after exposure, followed by recovery within 5 days after irradiation. Neutron and photon doses that caused intestinal death resulted in greater mucosal breakdown with little or no evidence of mucosal recovery. The presence of fluid in the intestine and diarrhea, but not bacteremia or endotoxemia, were related to mucosal breakdown and recovery. Neither sepsis nor endotoxin could be detected in liver samples taken at autopsy from animals which died a short time earlier from intestinal injury. These results suggest that overt sepsis and endotoxemia do not play a significant role in the intestinal radiation syndrome

  7. Regulation of intestinal calcium absorption by luminal calcium content: role of intestinal alkaline phosphatase.

    Science.gov (United States)

    Brun, Lucas R; Brance, María L; Lombarte, Mercedes; Lupo, Maela; Di Loreto, Verónica E; Rigalli, Alfredo

    2014-07-01

    Intestinal alkaline phosphatase is a brush border enzyme that is stimulated by calcium. Inhibition of intestinal alkaline phosphatase increases intestinal calcium absorption. We hypothesized that intestinal alkaline phosphatase acts as a minute-to-minute regulatory mechanism of calcium entry. The aim of this study was to evaluate the mechanism by which intestinal luminal calcium controls intestinal calcium absorption. We performed kinetic studies with purified intestinal alkaline phosphatase and everted duodenal sacs and showed that intestinal alkaline phosphatase modifies the luminal pH as a function of enzyme concentration and calcium luminal content. A decrease in pH occurred simultaneously with a decrease in calcium absorption. The inhibition of intestinal alkaline phosphatase by l-phenylalanine caused an increase in calcium absorption. This effect was also confirmed in calcium uptake experiments with isolated duodenal cells. Changes in luminal pH arising from intestinal alkaline phosphatase activity induced by luminal calcium concentration modulate intestinal calcium absorption. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. Relationship between intestinal microflora imbalance and nonalcoholic fatty liver disease

    Directory of Open Access Journals (Sweden)

    MA Ruijuan

    2015-01-01

    Full Text Available The intestinal microecosystem is composed of natural microflora, intestinal epithelial cells, and intestinal mucosal immune system. Nonalcoholic fatty liver disease (NAFLD is a metabolic stress-induced liver injury associated with insulin resistance and genetic susceptibility. In recent years, there has been increasing evidence showing the involvement of imbalanced intestinal microflora in the pathogenesis of NAFLD. Overgrowth of intestinal microflora, increased permeability of intestinal mucosa, intestinal endotoxemia, and production of inflammatory cytokines play important roles in the development of NAFLD. Further studies on the relationship between intestinal microflora imbalance and the pathogenesis of NAFLD may shed light on the treatment and prevention of NAFLD.

  9. Gallstone ileus resulting in strong intestinal obstruction

    Directory of Open Access Journals (Sweden)

    Israel Szajnbok

    Full Text Available Mechanic intestinal obstruction, caused by the passage of biliary calculus from vesicle to intestine, through fistulization, although not frequent, deserve study due to the morbi-mortality rates. Incidence in elder people explains the association with chronic degenerative diseases, increasing complexity in terms of therapy decision. Literature discusses the need and opportunity for the one or two-phase surgical attack of the cholecystenteric fistule, in front of the resolution on the obstructive urgency and makes reference to Gallstone Ileus as an exception for strong intestinal obstruction. The more frequent intestinal obstruction observed is when it occurs a Gallstone Ileus impacting in terms of ileocecal valve. The authors submit a Gallstone Ileus manifestation as causing strong intestinal obstruction, discussing aspects regarding diagnostic and treatment.

  10. Multispectral tissue characterization for intestinal anastomosis optimization

    Science.gov (United States)

    Cha, Jaepyeong; Shademan, Azad; Le, Hanh N. D.; Decker, Ryan; Kim, Peter C. W.; Kang, Jin U.; Krieger, Axel

    2015-10-01

    Intestinal anastomosis is a surgical procedure that restores bowel continuity after surgical resection to treat intestinal malignancy, inflammation, or obstruction. Despite the routine nature of intestinal anastomosis procedures, the rate of complications is high. Standard visual inspection cannot distinguish the tissue subsurface and small changes in spectral characteristics of the tissue, so existing tissue anastomosis techniques that rely on human vision to guide suturing could lead to problems such as bleeding and leakage from suturing sites. We present a proof-of-concept study using a portable multispectral imaging (MSI) platform for tissue characterization and preoperative surgical planning in intestinal anastomosis. The platform is composed of a fiber ring light-guided MSI system coupled with polarizers and image analysis software. The system is tested on ex vivo porcine intestine tissue, and we demonstrate the feasibility of identifying optimal regions for suture placement.

  11. ACUTE INTESTINAL INFECTIONS: THERAPEUTICAL TACTICS IN CHILDREN

    Directory of Open Access Journals (Sweden)

    A.N. Surkov

    2011-01-01

    Full Text Available Acute intestinal infections are quite common among children. Their clinical presentations include intoxication syndrome (drowsiness, low appetite, fever etc, infectious toxic syndrome (toxicosis with exicosis, neurotoxicosi, hypovolemic or infectious-toxic shockand diarrhea syndrome. Sometimes intestinal infections can be quite severe and even lethal. However disease duration and outcome depend on timelines and adequacy of prescribed treatment. Main guidelines of intestinal infections treatment include probiotics. That is why the right choice of probiotics is important for a pediatrician. The article contains basic information upon etiopathogenesis, classification, diagnostic criteria and acute pediatric intestinal infections treatment guidelines.Key words: acute intestinal infections, etiopathogenesis, diagnostic criteria, treatment, probiotics, children. (Voprosy sovremennoi pediatrii — Current Pediatrics. — 2011; 10 (6: 141–147

  12. Regional specialization within the intestinal immune system

    DEFF Research Database (Denmark)

    Mowat, Allan M.; Agace, William Winston

    2014-01-01

    The intestine represents the largest compartment of the immune system. It is continually exposed to antigens and immunomodulatory agents from the diet and the commensal microbiota, and it is the port of entry for many clinically important pathogens. Intestinal immune processes are also increasingly...... implicated in controlling disease development elsewhere in the body. In this Review, we detail the anatomical and physiological distinctions that are observed in the small and large intestines, and we suggest how these may account for the diversity in the immune apparatus that is seen throughout...... the intestine. We describe how the distribution of innate, adaptive and innate-like immune cells varies in different segments of the intestine and discuss the environmental factors that may influence this. Finally, we consider the implications of regional immune specialization for inflammatory disease...

  13. Diseño y proceso productivo de una caja isoterma

    OpenAIRE

    SORIANO BUENACHE, MARCOS

    2017-01-01

    [EN] The work verses on the design and production process of an isothermal bodyworks [ES] El trabajo versa sobre el diseño y el proceso productivo de una caja isoterma. Soriano Buenache, M. (2017). Diseño y proceso productivo de una caja isoterma. http://hdl.handle.net/10251/88081. TFGM

  14. Descripción de los sistemas de control digital de procesos

    Directory of Open Access Journals (Sweden)

    Adolfo Mora Villate

    1986-01-01

    Full Text Available Este articulo se ocupa de exponer a grandes rasgos las funciones que cumplen los computadores aplicados al control de procesos Industriales, así como de presentar las principales configuraciones de los sistemas de control digital de procesos.

  15. [Neovagina with intestine: 13 cases].

    Science.gov (United States)

    Parente, A; Molina, E; Cerdá, J; Cañizo, A; Rodriguez, A; Laín, A; Fanjul, M; Vázquez, J

    2008-01-01

    The absence or hipoplasia vaginal can turn out to be isolated, associated with ambiguous genitalia, or as anatomical variant in a syndrome of sewer. The fundamental aim in the creation of a new vagina is: to obtain a good aesthetic result, to fulfil functional criteria (elasticity, sensibility, physiological inclination) and to improve the quality of life of the patients avoiding the use of molds and minimizing the morbidity of the zones donors. In this work let's sense beforehand our experience in the accomplishment of neovaginas with intestine. We analyze the clinical record of 13 patients treated surgically in the last ten years. We differentiate two groups according to the age, the diagnosis and the type of surgery: a) the first group of 8 patients present syndrome of insensibility to the androgens (4), syndrome of Rokitansky (2), extrofia of sewer (1) and mixed gonadal disgenesia (1). This group of patients were controlled in the adolescence by an average of age of 19 years (11-35 years), they fulfilling a neovagina with sigma; b) the second group of 5 patients with sewer (3), extrofia of sewer (1) and congenital suprarrenal hiperplasia (1). This group was controlled prematurely by a middle ages of one year (4 months-3 years). The intestinal segment used as neovagina was sigma (2), ileon (2) and rectum (1), and was performed during the surgical correction of her congenital malformation. Two patients have presented intestinal obstruction in the postoperatory immediate one. Four patients have needed removal of a small vaginal prolapse, and three have needed vaginal transitory expansions for introit stenosis. The long-term evolution has been favorable with an excellent aesthetic aspect. Four patients recount sexual fully satisfactory relations. We believe that the neovagina with sigma is at present the best option in patients with absence or hipoplasia vaginal. The advantages are the possibility of precocious and one time correction, a neovagina of dimensions and

  16. Procesos de Lévy: propiedades e integración estocástica

    OpenAIRE

    Chávez Bedoya Mercado, Luis Carlos

    2006-01-01

    Los procesos de Lévy son procesos estocásticos que poseen incrementos estacionarios e independientes, y además son continuos en probabilidad. Muchas de las investigaciones teóricas y aplicaciones actuales de los procesos estocásticos en ingeniería, economía y finanzas están basadas en procesos de Lévy; tomamos esto como motivación para profundizar en el estudio de dichos procesos así como para difundir sus aspectos teóricos y prácticos. Asimismo, el cálculo estocástico es una de las principal...

  17. [Intestinal endometriosis - a case report].

    Science.gov (United States)

    Krzemiński, Sławomir

    2017-03-21

    Endometriosis intestines due to its non-specific symptoms can pose diagnostic problems, a lack of or incorrect treatment worsens the quality of life, sometimes leading to serious complications. The differential diagnosis of abdominal pain, especially in patients of reproductive age should be taken disease into account. Often abdominal pain in young women are classified as a functional gastrointestinal disorder, and only carefully collected intelligence allows you to focus on the diagnosis of endometriosis, especially if the symptoms significantly impair quality of life. A woman 32 year old who was admitted to the department of gastroenterology because of increasing pain in the abdomen. Due to the deteriorating condition of the patient, the characteristics of mechanical obstruction on imaging studies was transferred to the surgical ward with suspected Crohn's disease. She was treated surgically. Histopathological examination found endometriosis. Endometriosis outside the sex system can lead to serious complications.

  18. Kaposiform hemangioendothelioma causing intestinal obstruction

    Directory of Open Access Journals (Sweden)

    Bassel Salman

    2018-01-01

    Full Text Available A previously healthy toddler with bilious vomiting and erythematous gluteal rash over 2 weeks had intermittent pain, constipation and decreased appetite. All labs were negative with the exception of fecal occult blood. Abdominal x-ray and ultrasound revealed dilated air-filled loops of bowel and partial small bowel obstruction. After persistent worsening abdominal pain and vomiting a CT scan with IV contrast (Fig. 1 suggested small bowel obstruction. Emergent surgery was performed and diagnostic laparoscopy revealed about 61 cm of necrotic bowel causing stricture formation and mesenteric shortening in the distal small bowel. 56 cm of inflamed bowel was resected with end-to-end anastomosis. Final pathology report indicated diffuse intestinal angiomatosis with transmural involvement and focal erosion consistent with KHE (Fig. 2. Presentation is varied, consists of cutaneous lesion, retroperitoneal mass, intestinal obstruction, jaundice, intussusception, or multifocal neoplasms. Complete surgical resection with wide margins is the best therapeutic option and has achieved the best outcomes. If not treated in sufficient time, KHE has a relatively high mortality rate of 30%, with most deaths occurring due to its locally invasive effects [5]. There are limited reports of identifying features of KHE on imaging. Of 165 cases of KHE none were presented in the small bowel [5]. We report the unique case of KHE presenting as a hypervascular mass causing obstruction in the distal small bowel. Although extremely rare, KHE should be considered as a reason for severe GI stricture or obstruction in infants and children in obscure cases and included in the differential.

  19. The significance of intestinal apoptosis

    International Nuclear Information System (INIS)

    Potten, C.S.

    1997-01-01

    Apoptosis occurs at a low level spontaneously in the small intestine (SI). The levels can be raised by a variety of cytotoxic agents including radiation. The apoptosis induced by radiation, and some drugs and the spontaneous apoptosis, show some specificity for the stem cells in the small intestinal crypt. In the colon, these agents target transit cells in the mid crypt. p53 expression is elevated at the same time as apoptosis in the SI but not in the cells undergoing apoptosis. The expression of bcl-2, a survival gene, is largely absent in the SI, but is expressed, albeit weakly, in the stem cells in the colon. Spontaneous apoptosis is observed in p53 null mice which also develop normally suggesting that spontaneous and developmental apoptosis are p53 independent and that spontaneous apoptosis is part of the homeostatic mechanisms maintaining stem cell numbers. Radiation induced apoptosis is completely absent at these early times post-irradiation in p53 nulls. In bel-2 null mice, the levels of spontaneous and radiation induced apoptosis are elevated in the colon. Bax, a death gene, is expressed on the villus and inter-crypt table in the colon suggesting that cells at the end of their lifespan initiate apoptosis. It has been suggested that apoptosis in the SI is a protective mechanism against carcinogenesis in the stem cells of the SI which rarely develops cancer. Cells that possess genetic damage detected. In the large bowel, this mechanism is not effective due to the action of bcl-2. Thus stem cells may persist in this tissue with genetic damage resulting in a higher cancer risk. Furthermore, the lack of spontaneous apoptosis in the colon may result in a gradual increase of the stem cells with time resulting in more ells at risk. (author)

  20. Alpha-ketoglutarate (AKG) lowers body weight and affects intestinal innate immunity through influencing intestinal microbiota.

    Science.gov (United States)

    Chen, Shuai; Bin, Peng; Ren, Wenkai; Gao, Wei; Liu, Gang; Yin, Jie; Duan, Jielin; Li, Yinghui; Yao, Kang; Huang, Ruilin; Tan, Bie; Yin, Yulong

    2017-06-13

    Alpha-ketoglutarate (AKG), a precursor of glutamate and a critical intermediate in the tricarboxylic acid cycle, shows beneficial effects on intestinal function. However, the influence of AKG on the intestinal innate immune system and intestinal microbiota is unknown. This study explores the effect of oral AKG administration in drinking water (10 g/L) on intestinal innate immunity and intestinal microbiota in a mouse model. Mouse water intake, feed intake and body weight were recorded throughout the entire experiment. The ileum was collected for detecting the expression of intestinal proinflammatory cytokines and innate immune factors by Real-time Polymerase Chain Reaction. Additionally, the ileal luminal contents and feces were collected for 16S rDNA sequencing to analyze the microbial composition. The intestinal microbiota in mice was disrupted with an antibiotic cocktail. The results revealed that AKG supplementation lowered body weight, promoted ileal expression of mammalian defensins of the alpha subfamily (such as cryptdins-1, cryptdins-4, and cryptdins-5) while influencing the intestinal microbial composition (i.e., lowering the Firmicutes to Bacteroidetes ratio). In the antibiotic-treated mouse model, AKG supplementation failed to affect mouse body weight and inhibited the expression of cryptdins-1 and cryptdins-5 in the ileum. We concluded that AKG might affect body weight and intestinal innate immunity through influencing intestinal microbiota.

  1. [Effect of perioperative intestinal probiotics on intestinal flora and immune function in patients with colorectal cancer].

    Science.gov (United States)

    Zhu, Dajian; Chen, Xiaowu; Wu, Jinhao; Ju, Yongle; Feng, Jing; Lu, Guangsheng; Ouyang, Manzhao; Ren, Baojun; Li, Yong

    2012-08-01

    To investigate the effect of perioperative application of intestinal probiotics to substitute oral intestinal antimicrobial agents on intestinal flora and immune function in surgical patients with colorectal cancer. Sixty patients with colorectal cancer undergoing elective laparoscopic radical surgery were randomized to receive preoperative bowel preparation using oral intestinal antimicrobial agents (n=20) or using oral intestinal probiotics (Jinshuangqi Tablets, 2.0 g, 3 times daily) since the fifth day before the operation and at 24 h after the operation for 7 consecutive days. Upon admission and 7 days after the operation, fecal samples and fasting peripheral venous blood were collected from the patients to examine the intestinal flora and serum levels of interleukin-2 (IL-2), IgA, IgG, and IgM, NK cell activity, T lymphocytes subsets CD3(+), CD4(+), CD8(+) and CD4(+)/CD8(+) ratio. At 7 days after the operation, the patients receiving probiotics showed significantly increased counts of intestinal Bifidobacterium, Lactobacillus, and Enterococcus (Pprobiotics group compared with those in patients with conventional intestinal preparation (Pprobiotics to replace preoperative oral intestinal antimicrobial agents can effectively correct intestinal flora imbalance and improve the immune function of surgical patients with colorectal cancer.

  2. Diffused and sustained inhibitory effects of intestinal electrical stimulation on intestinal motility mediated via sympathetic pathway.

    Science.gov (United States)

    Zhao, Xiaotuan; Yin, Jieyun; Wang, Lijie; Chen, Jiande D Z

    2014-06-01

    The aims were to investigate the energy-dose response effect of intestinal electrical stimulation (IES) on small bowel motility, to compare the effect of forward and backward IES, and to explore the possibility of using intermittent IES and mechanism of IES on intestinal motility. Five dogs implanted with a duodenal cannula and one pair of intestinal serosal electrodes were studied in five sessions: 1) energy-dose response study; 2) forward IES; 3) backward IES; 4) intermittent IES vs. continuous IES; 5) administration of guanethidine. The contractile activity and tonic pressure of the small intestine were recorded. The duration of sustained effect after turning off IES was manually calculated. 1) IES with long pulse energy dose dependently inhibited contractile activity and tonic pressure of the small intestine (p intestine depended on the energy of IES delivered (p intestine. 5) Guanethidine blocked the inhibitory effect of IES on intestinal motility. IES with long pulses inhibits small intestinal motility; the effect is energy-dose dependent, diffused, and sustained. Intermittent IES has the same efficacy as the continuous IES in inhibiting small intestinal motility. Forward and backward IES have similar inhibitory effects on small bowel motility. This IES-induced inhibitory effect is mediated via the sympathetic pathway. © 2013 International Neuromodulation Society.

  3. Vitamin D and intestinal calcium absorption.

    Science.gov (United States)

    Christakos, Sylvia; Dhawan, Puneet; Porta, Angela; Mady, Leila J; Seth, Tanya

    2011-12-05

    The principal function of vitamin D in calcium homeostasis is to increase calcium absorption from the intestine. Calcium is absorbed by both an active transcellular pathway, which is energy dependent, and by a passive paracellular pathway through tight junctions. 1,25Dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) the hormonally active form of vitamin D, through its genomic actions, is the major stimulator of active intestinal calcium absorption which involves calcium influx, translocation of calcium through the interior of the enterocyte and basolateral extrusion of calcium by the intestinal plasma membrane pump. This article reviews recent studies that have challenged the traditional model of vitamin D mediated transcellular calcium absorption and the crucial role of specific calcium transport proteins in intestinal calcium absorption. There is also increasing evidence that 1,25(OH)(2)D(3) can enhance paracellular calcium diffusion. The influence of estrogen, prolactin, glucocorticoids and aging on intestinal calcium absorption and the role of the distal intestine in vitamin D mediated intestinal calcium absorption are also discussed. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  4. Estudio comparativo de la productividad y calidad obtenidas en la soldadura de tubos de calidad T9 empleados en el sector petroquímico, mediante los procesos TIG, HW-TIG y PAW Comparative study of productivity and quality obtained in tube welding quality T9 employees in the petrochemical industry, through TIG, HW-TIG and PAW processes

    Directory of Open Access Journals (Sweden)

    César García González

    2012-09-01

    Full Text Available Tradicionalmente, la fabricación soldada de tuberías de acero Cr-Mo empleadas en serpentines de hornos para la industria petroquímica se ha venido realizando de forma masiva mediante procesos de baja productividad, principalmente TIG para la pasada de raíz y SMAW para las pasadas de relleno, ambos manuales. En este estudio se muestran los resultados de la investigación realizada por el Centro Tecnológico AIMEN, en relación al empleo de tecnologías de alto rendimiento, concretamente TIG, HW-TIG y PAW robotizadas, aplicadas a los mismos materiales y productos. De este modo se calculan y comparan cuatro índices de productividad: Tiempo de Soldadura, Tasa de Deposición, Material Depositado y Volumen de Gas Consumido. El objetivo del estudio es contribuir a la reducción de los tiempos de producción, de los costes de fabricación, y a la mejora de la calidad del producto.Traditionally, the manufacture of welded Cr-Mo steel pipes used in furnace coils for petrochemical industry has been carried out on a massive scale by low productivity processes, mainly TIG for root pass and SMAW for layers of filling run, both of them manuals. This study presents the results of a research, conducted by AIMEN Technology Centre, related to the use of high performance technologies, specifically robotic processes such as TIG, TIG-HW and PAW, applied to the same materials and products. Thus, four productivity ratios have been calculated and compared: welding time, deposition rate, deposited material and volume of consumed gas. The aim of the study is to contribute to the reduction of the production time, manufacturing costs and to the improvement of the product quality.

  5. Intestinal lineage commitment of embryonic stem cells.

    Science.gov (United States)

    Cao, Li; Gibson, Jason D; Miyamoto, Shingo; Sail, Vibhavari; Verma, Rajeev; Rosenberg, Daniel W; Nelson, Craig E; Giardina, Charles

    2011-01-01

    Generating lineage-committed intestinal stem cells from embryonic stem cells (ESCs) could provide a tractable experimental system for understanding intestinal differentiation pathways and may ultimately provide cells for regenerating damaged intestinal tissue. We tested a two-step differentiation procedure in which ESCs were first cultured with activin A to favor formation of definitive endoderm, and then treated with fibroblast-conditioned medium with or without Wnt3A. The definitive endoderm expressed a number of genes associated with gut-tube development through mouse embryonic day 8.5 (Sox17, Foxa2, and Gata4 expressed and Id2 silent). The intestinal stem cell marker Lgr5 gene was also activated in the endodermal cells, whereas the Msi1, Ephb2, and Dcamkl1 intestinal stem cell markers were not. Exposure of the endoderm to fibroblast-conditioned medium with Wnt3A resulted in the activation of Id2, the remaining intestinal stem cell markers and the later gut markers Cdx2, Fabp2, and Muc2. Interestingly, genes associated with distal gut-associated mesoderm (Foxf2, Hlx, and Hoxd8) were also simulated by Wnt3A. The two-step differentiation protocol generated gut bodies with crypt-like structures that included regions of Lgr5-expressing proliferating cells and regions of cell differentiation. These gut bodies also had a smooth muscle component and some underwent peristaltic movement. The ability of the definitive endoderm to differentiate into intestinal epithelium was supported by the vivo engraftment of these cells into mouse colonic mucosa. These findings demonstrate that definitive endoderm derived from ESCs can carry out intestinal cell differentiation pathways and may provide cells to restore damaged intestinal tissue. Copyright © 2010 International Society of Differentiation. Published by Elsevier B.V. All rights reserved.

  6. El proceso evaluativo en programas con modalidad innovadora

    Directory of Open Access Journals (Sweden)

    Martínez de Acosta Carmen H.

    1999-12-01

    Full Text Available

    This study has an exploratory, descriptive, categoric design by which a content analysis was done in order to identified and categorizes different quantitative and qualitative indicators for the evaluation of Master' s Program in an innovative modality. The following categories where proposed: organizational, curricular, and professional profile. The study was, done with an integrate framework in which it is an expectation that the evaluation helps in the decision making process. The sample selection was done by convenience and it included 10 national and 5 international academic programs at Specialization and Magister level, all of them in innovative modalities. The results reflected 5 categories and 34 indicators for the evaluation of the organizational component; 13 categories and 57 indicators for the evaluation of the curricular component; and 5 categories and 26 indicators for the evaluation of the occupational component. As a final result, all of the indicators where Iinked together in an integrated evaluation proposal in which the categories and indicators are shown as well as the need of implementation by theconstruction of an evaluation process with a critical, participate and plural approach.

    El estudio corresponde a un diseño de tipo exploratorio, descriptivo, categórico. Mediante el análisis de contenido se identificaron y categorizaron diferentes indicadores cuantitativos y cualitativos para la evaluación de los componentes organizacional, curricular y de desempeño del programa de maestría, en modalidad innovadora dentro del marco de una conceptualización integral en la cual se espera que el proceso evaluativo apoye la toma de decisiones. De manera intencional, la muestra seleccionó diez programas académicos nacionales y cinco internacionales que ofertan programas a nivel de especialización y maestría en modalidades innovadoras. Los resultados arrojaron cinco categorías y treinta y cuatro indicadores para el

  7. Transcriptome changes during intestinal cell differentiation

    DEFF Research Database (Denmark)

    Tadjali, Mehrdad; Seidelin, Jakob B; Olsen, Jørgen Lillelund

    2002-01-01

    by a general down-regulation of genes in the low abundance class. Similar results were found using mouse small intestinal crypt and villus cells, suggesting that the phenomenon also occurs in the intestine in vivo. The expression data were subsequently used in a search for markers for subsets of epithelial...... cells by performing reverse transcriptase-polymerase chain reaction on RNA extracted from laser dissected intestinal crypt and villi. In a screen of eight transcripts one - SART3 - was identified as a marker for human colonic crypts....

  8. Recreating Intestinal Peristalsis in the Petri Dish.

    Science.gov (United States)

    Espinosa-Luna, Rosa; Barajas-Espinosa, Alma R; Ochoa-Cortez, Fernando; Barajas-López, Carlos

    2018-01-01

    Here we describe a culture technique of cells dissociated from the external muscularis of the guinea pig small intestine, which allows us to maintain all the elements involved in the intestinal peristaltic reflex. After a few days in culture, these cells reorganize to form a small group of cells that permit the generation of pacemaker activity, spontaneous contractions, and the development of inhibitory and excitatory junction potentials in the petri dish, all elements involved in the peristaltic reflex. Therefore, these co-cultures are suitable to study the cellular and molecular aspects related to the development, maintenance, and modulation of motor intestinal functions.

  9. Intestinal lengthening: an experimental and clinical review.

    Science.gov (United States)

    Bianchi, A

    1984-01-01

    Small intestinal lengthening by the Bianchi procedure has now had successful clinical application in children and neonates with the short-bowel syndrome. This paper reviews the background experimental work and clinical cases so far treated. A personal case of intestinal lengthening in a 7-week-old baby with 35 cm jejunum is described in detail. Intestinal lengthening appears to reduce dependence on parenteral nutrition, thus allowing earlier establishment of total enteral alimentation. The procedure may therefore have a useful place in the overall management of the short-bowel syndrome. Images Figure 3. A Figure 3. B Figure 3. C Figure 3. D PMID:6471060

  10. Procesos constituyentes y cortes constitucionales: una perspectiva comparada

    Directory of Open Access Journals (Sweden)

    RODRIGO GONZÁLEZ-QUINTERO

    2009-01-01

    Full Text Available Durante el último tercio del siglo XX, dentro de un marco que se podría calificar como de una explosión del constitucionalismo, nuevas constituciones fueron adoptadas en España, Corea del Sur y Colombia. Cabe destacar que estos nuevos textos fundamentales establecieron cortes constitucionales. El análisis comparado de los procesos constituyentes acaecidos en los tres países, que este artículo ofrece, ilustra ciertas diferencias y similitudes entre los mismos. No obstante, por encima de éstas y aquéllas, el argumento es que en diferentes partes del globo, muy distantes en lugar y algo en tiempo, y bajo circunstancias específicas de crisis institucional, tres sociedades políticas y sus respectivos líderes acometieron la tarea de superar dicha crisis a través de la adopción de un nuevo texto constitucional o la modificación del ya existente. De forma más particular, el artículo busca demostrar que el establecimiento de cortes constitucionales implicaba, en esos tres países, la vigencia a futuro del consenso constitucional como superación de la crisis pasada.

  11. PROCESOS DE CANONIZACIÓN DE LA LITERATURA CHILENA

    Directory of Open Access Journals (Sweden)

    Iván Carrasco M

    2008-11-01

    Full Text Available Este trabajo estudia los procesos de canonización en la literatura chilena y sus relaciones con las identidades socioculturales, desde la generación romántica de 1852 (ó 1842 hasta la última década del siglo XX, delimitando sus autores, textos y metatextos canónicos. La hipótesis que organiza el trabajo es que la literatura chilena se inició en torno a un canon único, que ha sido reemplazado a través del tiempo por cánones plurales, paralelos y contrapuestos.This paper studies the literary canonization processes in Chilean literature andtheir relations with social and cultural identities. Its purpose is to establish the boundaries of the texts and metatexts written by Chilean canonical authors, starting with the romantic generation of 1852 (or 1842 and ending up with the works published in the last decade of 'the XX century. The hypothesis of this essay is that Chilean literature can be said to have its origins focused on a single canon, which is later replaced by a series of plural, parallel and even opposite canons.

  12. Expectativas, logros y frustraciones de un proceso de paz

    Directory of Open Access Journals (Sweden)

    Javier Giraldo Moreno

    2017-11-01

    Full Text Available Los diálogos de Paz entre el Gobierno de Colombia y la insurgencia de las FARC, iniciados formalmente en agosto de 2012, luego de un período previo de exploración, y concluidos formalmente en noviembre de 2016 con la firma de un extenso Acuerdo que ha sufrido múltiples enmiendas y que no acaba de consolidarse frente a perspectivas constantes de nuevas enmiendas y amenazas persistentes de desconocimiento e incumplimiento, han centrado el debate político interno y externo. A nivel interno la polarización se agudiza progresivamente; a nivel externo produce curiosidades y expectativas por lo novedoso de algunas de sus soluciones. En los últimos 34 años Colombia había vivido 5 prolongados procesos de paz, todos fracasados, si se entiende la paz como algo de interés nacional. Sólo entre los gobiernos de Barco y Gaviria (1986-94 hubo desmovilizaciones de varias estructuras armadas pequeñas o diezmadas que no se proyectaron en ninguna reforma social sino en prebendas puntuales para cada desmovilizado. Ello ha incidido en una cierta banalización de la paz, no pocas veces utilizada como incentivo de politiquerías electorales.

  13. Las Olas del Renovación del Processo, Neoconstitucionalismo y el Proceso Democrático en el Nuevo Código de Proceso Civil

    Directory of Open Access Journals (Sweden)

    Marcos Paulo Andrade Bianchini

    2016-10-01

    Full Text Available Este trabajo pretende revisar olas del renovación del proceso, neoconstitucionalismo y el proceso democrático en el nuevo código de procedimiento civil. En este trabajo se utilizaron los métodos deductivos y dogmáticos y bibliográficos. Gracias-si proceso metodológico histórico y comparativo. La investigación se divide en tres partes: olas de renovación proceso, contradictorio tridimensional y democrática en nuevo código de Procedimiento Civil-NCPC. Actualmente la tercera ola renovatória el proceso trae nuevos temas que merecen consideración, entre ellos la NCPC, que consagra la aplicación de contradictorio en su visión tridimensional conocimiento-reacción-influencia. El derecho a un proceso de confrontación es el fundamento de las decisiones democráticas. La NCPC ha establecido parámetros para orientar la actividad judicial, establecer un núcleo mínimo contenido cuando la entrega de los juicios, positivando el razonamiento analítico, indispensable para el estado democrático de derecho y debido proceso, puesto que alcanzar uno de los ámbitos de las partes contradictorias, el derecho tridimensionales de influir en la decisión. Referido para razones del estado, así como para evitar la voluntad, en consonancia con el principio de eficiencia, mejorando y mejorando el derecho básico de la motivación judicial actúa, como el artículo 93, IX de la Constitución Federal. Todos estos desarrollos contribuyan en gran medida el proceso de democratización. Las ideologías del proceso democrático en la NCPC, añadido al principio de contradicción en su visión tridimensional, así como las razones legítimas y decisiones calificadas, representan un avance significativo hacia la eficiencia.

  14. Peptidases Compartmentalized to the Ascaris suum Intestinal Lumen and Apical Intestinal Membrane

    Science.gov (United States)

    Rosa, Bruce A.

    2015-01-01

    The nematode intestine is a tissue of interest for developing new methods of therapy and control of parasitic nematodes. However, biological details of intestinal cell functions remain obscure, as do the proteins and molecular functions located on the apical intestinal membrane (AIM), and within the intestinal lumen (IL) of nematodes. Accordingly, methods were developed to gain a comprehensive identification of peptidases that function in the intestinal tract of adult female Ascaris suum. Peptidase activity was detected in multiple fractions of the A. suum intestine under pH conditions ranging from 5.0 to 8.0. Peptidase class inhibitors were used to characterize these activities. The fractions included whole lysates, membrane enriched fractions, and physiological- and 4 molar urea-perfusates of the intestinal lumen. Concanavalin A (ConA) was confirmed to bind to the AIM, and intestinal proteins affinity isolated on ConA-beads were compared to proteins from membrane and perfusate fractions by mass spectrometry. Twenty-nine predicted peptidases were identified including aspartic, cysteine, and serine peptidases, and an unexpectedly high number (16) of metallopeptidases. Many of these proteins co-localized to multiple fractions, providing independent support for localization to specific intestinal compartments, including the IL and AIM. This unique perfusion model produced the most comprehensive view of likely digestive peptidases that function in these intestinal compartments of A. suum, or any nematode. This model offers a means to directly determine functions of these proteins in the A. suum intestine and, more generally, deduce the wide array functions that exist in these cellular compartments of the nematode intestine. PMID:25569475

  15. Pathogen invasion changes the intestinal microbiota composition and induces innate immune responses in the zebrafish intestine.

    Science.gov (United States)

    Yang, Hui-Ting; Zou, Song-Song; Zhai, Li-Juan; Wang, Yao; Zhang, Fu-Miao; An, Li-Guo; Yang, Gui-Wen

    2017-12-01

    Numerous bacteria are harbored in the animal digestive tract and are impacted by several factors. Intestinal microbiota homeostasis is critical for maintaining the health of an organism. However, how pathogen invasion affects the microbiota composition has not been fully clarified. The mechanisms for preventing invasion by pathogenic microorganisms are yet to be elucidated. Zebrafish is a useful model for developmental biology, and studies in this organism have gradually become focused on intestinal immunity. In this study, we analyzed the microbiota of normal cultivated and infected zebrafish intestines, the aquarium water and feed samples. We found that the predominant bacteria in the zebrafish intestine belonged to Gammaproteobacteria (67%) and that feed and environment merely influenced intestinal microbiota composition only partially. Intestinal microbiota changed after a pathogenic bacterial challenge. At the genus level, the abundance of some pathogenic intestinal bacteria increased, and these genera included Halomonas (50%), Pelagibacterium (3.6%), Aeromonas (2.6%), Nesterenkonia (1%), Chryseobacterium (3.4‰), Mesorhizobium (1.4‰), Vibrio (1‰), Mycoplasma (0.7‰) and Methylobacterium (0.6‰) in IAh group. However, the abundance of some beneficial intestinal bacteria decreased, and these genera included Nitratireductor (0.8‰), Enterococcus (0.8‰), Brevundimonas (0.7‰), Lactococcus (0.7‰) and Lactobacillus (0.4‰). Additionally, we investigated the innate immune responses after infection. ROS levels in intestine increased in the early stages after a challenge and recovered subsequently. The mRNA levels of antimicrobial peptide genes lectin, hepcidin and defensin1, were upregulated in the intestine after pathogen infection. These results suggested that the invasion of pathogen could change the intestinal microbiota composition and induce intestinal innate immune responses in zebrafish. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. Apple-peel intestinal atresia: enteroplasty for intestinal lengthening and primary anastomosis.

    Science.gov (United States)

    Onofre, Luciano Silveira; Maranhão, Renato Frota de Albuquerque; Martins, Elaine Cristina Soares; Fachin, Camila Girardi; Martins, Jose Luiz

    2013-06-01

    Apple-peel atresia (or Type-IIIb intestinal atresia) is an unusual type of jejunoileal atresia. They present with jejunal atresia near the ligament of Treitz and a foreshortened small bowel. Many surgical options have been used, but the optimal method of repair remains unclear. We present a case of a newborn with apple-peel intestinal atresia managed by enteroplasty for intestinal lengthening and primary anastomosis. Copyright © 2013 Elsevier Inc. All rights reserved.

  17. Intestinal Leiomyositis: A Cause of Chronic Intestinal Pseudo?Obstruction in 6 Dogs

    OpenAIRE

    Zacuto, A.C.; Pesavento, P.A.; Hill, S.; McAlister, A.; Rosenthal, K.; Cherbinsky, O.; Marks, S.L.

    2015-01-01

    Background Intestinal leiomyositis is a suspected autoimmune disorder affecting the muscularis propria layer of the gastrointestinal tract and is a cause of chronic intestinal pseudo?obstruction in humans and animals. Objective To characterize the clinical presentation, histopathologic features, and outcome of dogs with intestinal leiomyositis in an effort to optimize treatment and prognosis. Animals Six client?owned dogs. Methods Retrospective case series. Medical records were reviewed to de...

  18. Proceso de pruebas para pequeñas organizaciones desarrolladoras de software

    Directory of Open Access Journals (Sweden)

    Martha Lucía Rojas-Montes

    2015-05-01

    Full Text Available Definir un proceso de pruebas dentro de una organización puede ser valioso en la medida en que permita: (i incrementar la calidad del producto, (ii facilitar la comunicación y la comprensión entre los miembros del equipo, (iii apoyar la mejora continua del proceso, y (iv soportar la ejecución automática de ciertas tareas. En este sentido, este artículo propone un proceso liviano definido para guiar y apoyar la realización de las pruebas en pequeñas organizaciones desarrolladoras de software. El proceso propuesto incorpora técnicas de pruebas funcionales con el objetivo de concretar las actividades requeridas para evaluar la funcionalidad de un producto software de manera organizada y sistemática, especialmente aquellas que tienen que ver con el diseño y ejecución de las pruebas. Este proceso ha sido definido a partir del análisis de los procesos de pruebas existentes en algunos modelos de referencia y en diferentes estudios revisados de la literatura. Tras su ejecución exitosa en una pequeña empresa de desarrollo software, se ha observado que este proceso puede ser útil y práctico para llevar a cabo las pruebas de un producto software por organizaciones de este tipo.

  19. Interactions between the intestinal microbiota and innate lymphoid cells.

    Science.gov (United States)

    Chen, Vincent L; Kasper, Dennis L

    2014-01-01

    The mammalian intestine must manage to contain 100 trillion intestinal bacteria without inducing inappropriate immune responses to these microorganisms. The effects of the immune system on intestinal microorganisms are numerous and well-characterized, and recent research has determined that the microbiota influences the intestinal immune system as well. In this review, we first discuss the intestinal immune system and its role in containing and maintaining tolerance to commensal organisms. We next introduce a category of immune cells, the innate lymphoid cells, and describe their classification and function in intestinal immunology. Finally, we discuss the effects of the intestinal microbiota on innate lymphoid cells.

  20. Experiencing sexuality after intestinal stoma

    Directory of Open Access Journals (Sweden)

    Maria Angela Boccara de Paula

    2012-06-01

    Full Text Available OBJECTIVE: Identify the Social Representations (SR of ostomized people in terms of sexuality after the stoma. METHODS: An exploratory, descriptive, qualitative study using the Social Representation Theory with 15 ostomized people (8 females, mean age of 57.9 years, between August and September 2005. Data obtained from transcribed interviews were submitted to content analysis, resulting in the thematic unit "Giving new meaning to sexuality" and subthemes. RESULTS: The study demonstrated that the intestinal stoma interferes in the sexuality experience, showing that the meanings attributed to this experience are based on individual life stories, quality of personal relationships established in practice and perception of sexuality, despite the stoma. CONCLUSIONS: The Social Representations, in terms of experiencing sexuality after the stoma, are based on meanings attributed to the body, associated with daily life and present in the social imaginary. It is influenced by other factors, such as physiological changes resulting from the surgery and the fact of having or not a partner. Care taken during sexual practices provide greater security and comfort in moments of intimacy, resembling the closest to what ostomized people experienced before the stoma. The self-irrigation technique associated or not with the use of artificial occluder, has been attested by its users as a positive element that makes a difference in sexual practice after the stoma. The support to ostomized people should be comprehensive, not limited to technical care and disease, which are important, but not sufficient. The interdisciplinary health team should consider all aspects of the person, seeking a real meeting between subjects.OBJETIVO: Identificar as Representações Sociais (RS da pessoa estomizada intestinal sobre vivência da sexualidade após confecção do estoma. MÉTODOS: Estudo exploratório, descritivo, qualitativo do ponto de vista do referencial da Representa

  1. Congenital central hypoventilation syndrome and intestinal ...

    African Journals Online (AJOL)

    ... hypoventilation syndrome (CCHS), also called 'Ondine's curse', is characterised by an abnormal ventilatory response to progressive hypercapnia and sustained hypoxaemia. Neonates with this condition experience hypoventilation or apnoea while asleep. Patients may also have congenital intestinal aganglionosis (CIA), ...

  2. Intestinal perforation secondary to metastasic lung carcinoma

    Directory of Open Access Journals (Sweden)

    M. C. Álvarez Sánchez

    2014-11-01

    Full Text Available Secondary symptomatic gastrointestinal metastases from lung primary tumor are rare. They can cause a variety of clinical conditions such as perforation, obstruction and bleeding. Intestinal perforations of intestinal metastases have a very poor prognosis. We present a case of a patient with metastatic lung cancer who presents with intestinal perforation and pneumoperitoneum. A 67 year old male, immunosuppressed and smoker is diagnosed with acute abdomen secondary to perforation of a tumor of the terminal ileum, as well as three other similar injuries. Resection and anastomosis. The patient died two months after surgery. The final pathological diagnosis supports epidermoidide poorly differentiated lung carcinoma. It was concluded that given an intestinal perforation in a patient diagnosed with lung carcinoma, it shouldn´t be excluded the metastases origen . Surgery is a purely palliative procedure.

  3. Intestinal Colonization Dynamics of Vibrio cholerae

    Science.gov (United States)

    Almagro-Moreno, Salvador; Pruss, Kali; Taylor, Ronald K.

    2015-01-01

    To cause the diarrheal disease cholera, Vibrio cholerae must effectively colonize the small intestine. In order to do so, the bacterium needs to successfully travel through the stomach and withstand the presence of agents such as bile and antimicrobial peptides in the intestinal lumen and mucus. The bacterial cells penetrate the viscous mucus layer covering the epithelium and attach and proliferate on its surface. In this review, we discuss recent developments and known aspects of the early stages of V. cholerae intestinal colonization and highlight areas that remain to be fully understood. We propose mechanisms and postulate a model that covers some of the steps that are required in order for the bacterium to efficiently colonize the human host. A deeper understanding of the colonization dynamics of V. cholerae and other intestinal pathogens will provide us with a variety of novel targets and strategies to avoid the diseases caused by these organisms. PMID:25996593

  4. [Acute intestinal infections: current and upcoming vaccines].

    Science.gov (United States)

    Erlich, Paul; Sansonetti, Philippe J

    2013-01-01

    Currently, only a few licensed vaccines against intestinal infections are available. Existing vaccines have shown good efficacy when used by travelers in industrialized countries. However, these vaccines have lower efficacy in endemic areas with high prevalence of enteric pathogens. Current vaccines are too expensive to be efficiently distributed in endemic countries. Immune correlates of protection are not well defined for current licensed vaccines. A better understanding of protection mechanisms at the intestinal mucosal surfaces should allow the development of more efficient vaccines. Gut physiology and microbial composition play an important role in both physical integrity and immunological status of the gastro-intestinal tract. These parameters can partially explain the disparities observed in current vaccines efficiency. Several next-generation vaccines combined or not with adjuvant able to promote a strong mucosal response in the intestine, are under preclinical and clinical investigations. Copyright © 2012 Elsevier Masson SAS. All rights reserved.

  5. [THE INTESTINAL BARRIER, THE MICROBIOTA, MICROBIOME].

    Science.gov (United States)

    Mar'yanovich, A T

    2016-01-01

    The review examined modern condition of development directions physiology of digestion, like structure and function of the intestinal barrier, the microbiota of the digestive tract in its relations with the microorganism.

  6. Diversity and functions of intestinal mononuclear phagocytes

    DEFF Research Database (Denmark)

    Joeris, Thorsten; Müller-Luda, K; Agace, William Winston

    2017-01-01

    The intestinal lamina propria (LP) contains a diverse array of mononuclear phagocyte (MNP) subsets, including conventional dendritic cells (cDC), monocytes and tissue-resident macrophages (mφ) that collectively play an essential role in mucosal homeostasis, infection and inflammation. In the curr......The intestinal lamina propria (LP) contains a diverse array of mononuclear phagocyte (MNP) subsets, including conventional dendritic cells (cDC), monocytes and tissue-resident macrophages (mφ) that collectively play an essential role in mucosal homeostasis, infection and inflammation....... In the current review we discuss the function of intestinal cDC and monocyte-derived MNP, highlighting how these subsets play several non-redundant roles in the regulation of intestinal immune responses. While much remains to be learnt, recent findings also underline how the various populations of MNP adapt...

  7. Inflammasome in Intestinal Inflammation and Cancer

    Directory of Open Access Journals (Sweden)

    Tiago Nunes

    2013-01-01

    Full Text Available The activation of specific cytosolic pathogen recognition receptors, the nucleotide-binding-oligomerization-domain- (NOD- like receptors (NLRs, leads to the assembly of the inflammasome, a multimeric complex platform that activates caspase-1. The caspase-1 pathway leads to the upregulation of important cytokines from the interleukin (IL-1 family, IL-1β, and IL-18, with subsequent activation of the innate immune response. In this review, we discuss the molecular structure, the mechanisms behind the inflammasome activation, and its possible role in the pathogenesis of inflammatory bowel diseases and intestinal cancer. Here, we show that the available data points towards the importance of the inflammasome in the innate intestinal immune response, being the complex involved in the maintenance of intestinal homeostasis, correct intestinal barrier function and efficient elimination of invading pathogens.

  8. Upper intestinal and biliary tract endoprosthesis

    NARCIS (Netherlands)

    Tytgat, G. N.; Bartelsman, J. F.; den Hartog Jager, F. C.; Huibregtse, K.; Mathus-Vliegen, E. M.

    1986-01-01

    The endoscopic insertion of an endoprosthesis is now a standard procedure in the ultimate palliation of malignant obstructing upper gastrointestinal and biliary malignancy. The commercially available prostheses and introducing devices are adequate for the majority of upper intestinal cancers. For

  9. Epidemiology of small intestinal atresia in Europe

    DEFF Research Database (Denmark)

    Best, Kate E; Tennant, Peter W G; Addor, Marie-Claude

    2012-01-01

    The epidemiology of congenital small intestinal atresia (SIA) has not been well studied. This study describes the presence of additional anomalies, pregnancy outcomes, total prevalence and association with maternal age in SIA cases in Europe....

  10. Intestinal microbiota and HIV-1 infection

    Directory of Open Access Journals (Sweden)

    E. B. S. M. Trindade

    2007-01-01

    Full Text Available The intestinal microbiota consists of a qualitatively and quantitatively diverse range of microorganisms dynamically interacting with the host. It is remarkably stable with regard to the presence of microorganisms and their roles which, however, can be altered due to pathological conditions, diet composition, gastrointestinal disturbances and/or drug ingestion. The present review aimed at contributing to the discussion about changes in the intestinal microbiota due to HIV-1 infection, focusing on the triad infection-microbiota-nutrition as factors that promote intestinal bacterial imbalance. Intestinal microbiota alterations can be due to the HIV-1 infection as a primary factor or the pharmacotherapy employed, or they can be one of the consequences of the disease.

  11. Molecular characterization of intestinal protozoan parasites from ...

    African Journals Online (AJOL)

    Koffi Mathurin

    2014-02-17

    AJEST. African Journal of Environmental Science and. Technology. Full Length Research Paper. Molecular characterization of intestinal protozoan parasites from children facing diarrheal disease and associated risk factors in ...

  12. El trabajo en equipo en el Proceso Administrativo y de Compras en OPL Carga de Bucaramanga

    OpenAIRE

    Silva Remolina, Maria Andrea

    2014-01-01

    El proceso administrativo y de compras de OPL Carga tiene algunas falencias entre ellas: fallas en la Comunicación entre el personal operativo, no se realizan llamadas internas usando con frecuencia el email, produciendo la saturación de solicitudes las cuales terminan sin ser resueltas en cuanto a roles se refiere, no hay enfoque de procesos en vista que no se tiene claras las tareas de cada cargo, adicionalmente no hay claridad en los subprocesos, perjudicando el proceso con el a...

  13. Proceso de pruebas para pequeñas organizaciones desarrolladoras de software

    OpenAIRE

    Martha Lucía Rojas-Montes; Francisco José Pino-Correa; James Mauricio Martínez

    2015-01-01

    Definir un proceso de pruebas dentro de una organización puede ser valioso en la medida en que permita: (i) incrementar la calidad del producto, (ii) facilitar la comunicación y la comprensión entre los miembros del equipo, (iii) apoyar la mejora continua del proceso, y (iv) soportar la ejecución automática de ciertas tareas. En este sentido, este artículo propone un proceso liviano definido para guiar y apoyar la realización de las pruebas en pequeñas organizaciones desarrolladoras de softwa...

  14. El proceso de resiliencia en el desarrollo de la identidad lesbiana, gay y bisexual

    OpenAIRE

    Gil Hernández, Gloria Elena

    2007-01-01

    [ES] El proceso que lleva a la superación de adversidades consiguiendo con ello ganancias personales o grupales se denomina resiliencia. Este innovador marco de las ciencias sociales se presenta como idóneo para su aplicación al proceso de desarrollo positivo de la identidad lesbiana, gay y bisexual; siendo la homofobia social y la propia homofobia interiorizada la adversidad a superar. Con el objetivo de localizar y confirmar factores promotores del proceso, llevamos a cabo esta investigació...

  15. Proceso metodológico para seleccionar el problema de investigación

    OpenAIRE

    Torres Bardales, Coloníbol

    2014-01-01

    En la teoría de la investigación, no existe un proceso metodológico para seleccionar el problema de investigación, vacío que hemos cubierto con el trabajo, denominado: "PROCESO METODOLÓGICO PARA SELECCIONAR EL PROBLEMA DE INVESTIGACIÓN", cuyo principal objetivo es diseñar un proceso metodológico para seleccionar el problema de investigación, el que fue logrado aplicando los métodos: exegético, comparativo, histórico, inductivo y deductivo. Asimismo, la metodología aplicada permitió generar te...

  16. El discurso sobre el actual proceso de paz en la revista Semana (2012-2014)

    OpenAIRE

    Rincón Henao, Diana Marcela

    2016-01-01

    Este artículo presenta un análisis sobre el discurso del actual proceso de paz en la revista Semana entre los años 2012 a 2014, dada la relevancia de la participación de los medios de comunicación en un proceso trascendental para el futuro del país y la reconciliación de la sociedad. El objetivo es describir qué estrategias argumentativas usa la revista a partir de las noticias sobre el proceso de paz durante este periodo. La metodología utilizada se basó en los esquemas argumentativos (top...

  17. Modelo Gestión Documental para optimizar procesos en la ESPOCH

    OpenAIRE

    Reina Haro, Diego Marcelo

    2012-01-01

    Se presenta la propuesta de “Modelo de Gestión Documental para optimizar procesos en la ESPOCH”, con la visión de optimizar recursos en el proceso de remuneraciones de la institución. Los empleados, trabajadores, beneficiarios y encargados de producir, manipular y consultar este tipo de documentación obtendrán los conocimientos necesarios en cuanto a gestión documental y los procesos archivísticos para determinar el contenido de documentos, oficios, roles , etc. y mantenerlos organizados. Se ...

  18. LA CLAVE DEL ÉXITO DE UN PROCESO DE AUTOEVALUACIÓN: SU EQUIPO

    OpenAIRE

    Gutiérrez Huby, Ana María

    2014-01-01

    La experiencia obtenida en la conducción del proceso de autoevaluación de la Facultad de Ciencias Contables de esta universidad, el cual se encuentra en su fase final, nos da la certeza de expresar con mayor seguridad la importancia plena del rol que desempeñan los equipos de autoevaluación, ya que como ejecutores del proceso, tienen la responsabilidad de llevar a cabo de manera permanente y comprometida todas las acciones que involucra el proceso en todas las etapas del mismo. Por ello ...

  19. Evaluación de las capacidades humanas en el proceso de desarrollo de software

    OpenAIRE

    Acuña, Silvia T.; Sosa, Mabel; Figueroa, Saritha G.; Menini, María de los Ángeles

    2005-01-01

    En los modelos de proceso software actuales las personas son el factor menos formalizado, sin embargo, éstas presentan un comportamiento no determinístico y subjetivo que influye decisivamente en los resultados de la producción de software. Se ha desarrollado un Modelo del Proceso Software Orientado a las Capacidades que define los elementos del proceso software: actividades, productos, técnicas y personas; más los originales de esta investigación: estructuración del trabajo, roles y capac...

  20. Historia natural del proceso diagnóstico del cáncer de mama

    OpenAIRE

    Enrique Villarreal-Ríos; Verónica Escorcia-Reyes; Lidia Martínez-González; Emma Rosa Vargas-Daza; Liliana Galicia-Rodríguez; Roxana Cervantes-Becerra; José Martín López-Ramos

    2014-01-01

    OBJETIVO: Construir un modelo que explique la historia natural de proceso diagnóstico del cáncer de mama. MÉTODOS: Estudio transversal descriptivo con 245 de mujeres de 40 a 69 años, seleccionadas mediante muestreo aleatorio simple a quienes se realizó una mastografía y cumplieron con los principios del proceso diagnóstico de cáncer de mama. El diagnóstico se realizó por biopsia. Para el proceso diagnóstico se estimaron el porcentaje de pacientes atendidas en cada servicio, el total de pacien...

  1. Non-Meckel Small Intestine Diverticulitis

    Directory of Open Access Journals (Sweden)

    Shamim Ejaz

    2017-08-01

    Full Text Available Non-Meckel small intestine diverticulitis can have many manifestations and its management is not well-defined. We report 4 unselect cases of small intestine diverticulitis; all patients were seen by the same physician at the Emergency Center at The University of Texas MD Anderson Cancer Center between 1999 and 2014. The median age at diagnosis of these patients was 82 years (range, 76–87 years. All 4 patients presented with acute onset of abdominal pain, and computed tomography scans showed characteristics of small intestine diverticulitis unrelated to cancer. Most of the diverticula were found in the region of the duodenum and jejuno-ileal segments of the small intestine. The patients, even those with peripancreatic inflammation and localized perforation, were treated conservatively. Non-Meckel diverticulitis can be overlooked in the initial diagnosis because of the location of the diverticulosis, the age of the patient, and the rarity of the disease. Because patients with non-Meckel small intestine diverticulitis can present with acute abdominal pain, non-Meckel small intestine diverticulitis should be considered in the differential diagnosis of patients with acute abdominal pain, and computed tomography scans can help identify the condition. Because of the rarity of non-Meckel small intestine diverticulitis, few studies have been published, and the data are inconclusive about how best to approach these patients. Our experience with these 4 elderly patients indicates that non-Meckel small intestine diverticulitis can be treated conservatively, which avoids the potential morbidity and mortality of a surgical approach.

  2. Neuroimmune regulation during intestinal development and homeostasis.

    Science.gov (United States)

    Veiga-Fernandes, Henrique; Pachnis, Vassilis

    2017-02-01

    Interactions between the nervous system and immune system are required for organ function and homeostasis. Evidence suggests that enteric neurons and intestinal immune cells share common regulatory mechanisms and can coordinate their responses to developmental challenges and environmental aggressions. These discoveries shed light on the physiology of system interactions and open novel perspectives for therapy designs that target underappreciated neurological-immunological commonalities. Here we highlight findings that address the importance of neuroimmune cell units (NICUs) in intestinal development, homeostasis and disease.

  3. Intestinal angina. Report on two operated cases.

    Science.gov (United States)

    Solheim, K; Rosseland, A; Lund, B L

    1977-01-01

    In spite of the fact that the concept of intestinal angina is more than 70 years old, it is not generally accepted and only 400 cases of elective revascularization of the celiac/mesenteric arteries are reported in the literature. Two typical cases of intestinal angina treated with elective revascularization are presented and the pertinent literature is reviewed. An aggresive approach to the problem, followed by adequate reconstruction, is recommended.

  4. DIAGNOSIS AND MANAGEMENT OF SUBACUTE INTESTINAL OBSTRUCTION: A PROSPECTIVE STUDY

    OpenAIRE

    Amit; Anjani; Shaleen; Vikram; Prasheel

    2014-01-01

    Intestinal obstruction can be defined as impairment to the abnormal passage of intestinal contents that may be due to either mechanical obstruction or failure of normal intestinal motility in the absence of an obstructing lesion. Intestinal obstruction is the most common surgical disorder of the small intestine. SAIO implies incomplete obstruction. It has been defined in a number of ways and there are many gray zones in the treatment protocols. It is characterized by conti...

  5. Interactions between the intestinal microbiota and innate lymphoid cells

    OpenAIRE

    Chen, Vincent L; Kasper, Dennis L

    2013-01-01

    The mammalian intestine must manage to contain 100 trillion intestinal bacteria without inducing inappropriate immune responses to these microorganisms. The effects of the immune system on intestinal microorganisms are numerous and well-characterized, and recent research has determined that the microbiota influences the intestinal immune system as well. In this review, we first discuss the intestinal immune system and its role in containing and maintaining tolerance to commensal organisms. We...

  6. Functions and Signaling Pathways of Amino Acids in Intestinal Inflammation

    OpenAIRE

    Fang He; Chenlu Wu; Pan Li; Nengzhang Li; Dong Zhang; Quoqiang Zhu; Wenkai Ren; Yuanyi Peng

    2018-01-01

    Intestine is always exposed to external environment and intestinal microorganism; thus it is more sensitive to dysfunction and dysbiosis, leading to intestinal inflammation, such as inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), and diarrhea. An increasing number of studies indicate that dietary amino acids play significant roles in preventing and treating intestinal inflammation. The review aims to summarize the functions and signaling mechanisms of amino acids in intestin...

  7. Demographic analysis of mass-reared Anastrepha fraterculus (Diptera: Tephritidae in Tucumán, Argentina Análisis demográfico de la cría masiva de Anastrepha fraterculus (Diptera: Tephritidae en Tucumán, Argentina

    Directory of Open Access Journals (Sweden)

    Héctor E. Jaldo

    2007-06-01

    Full Text Available The life cycle of a lab-adapted mass reared strain of Anastrepha fraterculus at 24°C constant temperature was 41 days, including the preoviposition period. Mortality rates of 8%, 22%, 22%, 5%, and 43% were recorded for eggs, larvae, pupae, adults (preoviposition stage and adults (reproductive stage, respectively. The intrinsic rate of increase was 0.065, the net fecundity rate was 120.4, and the gross fecundity rate was 328.4. In a stable population, 22% would be eggs, 53% larvae, 18% pupae, 4% preoviposition adults, and 3% reproductive adults.El ciclo de vida de Anastrepha fraterculus en cría masiva a temperatura constante de 24°C fue de 41 días, incluyendo el período de preoviposición. Las mortalidades para huevo, larva, pupa, adultos en preoviposición y adultos reproductivos fueron de 8%, 22%, 22%, 5% y 43%, respectivamente. La tasa intrínseca de incremento natural fue de 0,065, la tasa de fertilidad neta fue de 120,4, y la tasa de fertilidad bruta fue de 328,4. En una población estable 22% debería ser huevos, 53% larvas, 18% pupas, 4% adultos en preoviposición y 3% adultos en etapa reproductiva.

  8. Intestinal perforation by an ingested foreign body

    Directory of Open Access Journals (Sweden)

    Gabriel Cleve Nicolodi

    Full Text Available Abstract Objective: To identify the computed tomography findings suggestive of intestinal perforation by an ingested foreign body. Materials and Methods: This was a retrospective study of four cases of surgically proven intestinal perforation by a foreign body, comparing the computed tomography findings with those described in the literature. Results: None of the patients reported having ingested a foreign body, all were over 60 years of age, three of the four patients used a dental prosthesis, and all of the foreign bodies were elongated and sharp. In all four patients, there were findings indicative of acute abdomen. None of the foreign bodies were identified on conventional X-rays. The computed tomography findings suggestive of perforation were thickening of the intestinal walls (in all four cases, increased density of mesenteric fat (in all four cases, identification of the foreign body passing through the intestinal wall (in three cases, and gas in the peritoneal cavity (in one case. Conclusion: In cases of foreign body ingestion, intestinal perforation is more common when the foreign body is elongated and sharp. Although patients typically do not report having ingested such foreign bodies, the scenario should be suspected in elderly individuals who use dental prostheses. A computed tomography scan can detect foreign bodies, locate perforations, and guide treatment. The findings that suggest perforation are thickening of the intestinal walls, increased mesenteric fat density, and, less frequently, gas in the peritoneal cavity, often restricted to the point of perforation.

  9. Intestinal perforation by an ingested foreign body*

    Science.gov (United States)

    Nicolodi, Gabriel Cleve; Trippia, Cesar Rodrigo; Caboclo, Maria Fernanda F. S.; de Castro, Francisco Gomes; Miller, Wagner Peitl; de Lima, Raphael Rodrigues; Tazima, Leandro; Geraldo, Jamylle

    2016-01-01

    Objective To identify the computed tomography findings suggestive of intestinal perforation by an ingested foreign body. Materials and Methods This was a retrospective study of four cases of surgically proven intestinal perforation by a foreign body, comparing the computed tomography findings with those described in the literature. Results None of the patients reported having ingested a foreign body, all were over 60 years of age, three of the four patients used a dental prosthesis, and all of the foreign bodies were elongated and sharp. In all four patients, there were findings indicative of acute abdomen. None of the foreign bodies were identified on conventional X-rays. The computed tomography findings suggestive of perforation were thickening of the intestinal walls (in all four cases), increased density of mesenteric fat (in all four cases), identification of the foreign body passing through the intestinal wall (in three cases), and gas in the peritoneal cavity (in one case). Conclusion In cases of foreign body ingestion, intestinal perforation is more common when the foreign body is elongated and sharp. Although patients typically do not report having ingested such foreign bodies, the scenario should be suspected in elderly individuals who use dental prostheses. A computed tomography scan can detect foreign bodies, locate perforations, and guide treatment. The findings that suggest perforation are thickening of the intestinal walls, increased mesenteric fat density, and, less frequently, gas in the peritoneal cavity, often restricted to the point of perforation. PMID:27818542

  10. Intestinal perforation by an ingested foreign body

    International Nuclear Information System (INIS)

    Nicolodi, Gabriel Cleve; Trippia, Cesar Rodrigo; Caboclo, Maria Fernanda F.S.; Castro, Francisco Gomes de; Miller, Wagner Peitl; Lima, Raphael Rodrigues de; Tazima, Leandro; Geraldo, Jamylle

    2016-01-01

    Objective: To identify the computed tomography findings suggestive of intestinal perforation by an ingested foreign body. Materials and Methods: This was a retrospective study of four cases of surgically proven intestinal perforation by a foreign body, comparing the computed tomography findings with those described in the literature. Results: None of the patients reported having ingested a foreign body, all were over 60 years of age, three of the four patients used a dental prosthesis, and all of the foreign bodies were elongated and sharp. In all four patients, there were findings indicative of acute abdomen. None of the foreign bodies were identified on conventional X-rays. The computed tomography findings suggestive of perforation were thickening of the intestinal walls (in all four cases), increased density of mesenteric fat (in all four cases), identification of the foreign body passing through the intestinal wall (in three cases), and gas in the peritoneal cavity (in one case). Conclusion: In cases of foreign body ingestion, intestinal perforation is more common when the foreign body is elongated and sharp. Although patients typically do not report having ingested such foreign bodies, the scenario should be suspected in elderly individuals who use dental prostheses. A computed tomography scan can detect foreign bodies, locate perforations, and guide treatment. The findings that suggest perforation are thickening of the intestinal walls, increased mesenteric fat density, and, less frequently, gas in the peritoneal cavity, often restricted to the point of perforation. (author)

  11. Intestinal perforation by an ingested foreign body.

    Science.gov (United States)

    Nicolodi, Gabriel Cleve; Trippia, Cesar Rodrigo; Caboclo, Maria Fernanda F S; de Castro, Francisco Gomes; Miller, Wagner Peitl; de Lima, Raphael Rodrigues; Tazima, Leandro; Geraldo, Jamylle

    2016-01-01

    To identify the computed tomography findings suggestive of intestinal perforation by an ingested foreign body. This was a retrospective study of four cases of surgically proven intestinal perforation by a foreign body, comparing the computed tomography findings with those described in the literature. None of the patients reported having ingested a foreign body, all were over 60 years of age, three of the four patients used a dental prosthesis, and all of the foreign bodies were elongated and sharp. In all four patients, there were findings indicative of acute abdomen. None of the foreign bodies were identified on conventional X-rays. The computed tomography findings suggestive of perforation were thickening of the intestinal walls (in all four cases), increased density of mesenteric fat (in all four cases), identification of the foreign body passing through the intestinal wall (in three cases), and gas in the peritoneal cavity (in one case). In cases of foreign body ingestion, intestinal perforation is more common when the foreign body is elongated and sharp. Although patients typically do not report having ingested such foreign bodies, the scenario should be suspected in elderly individuals who use dental prostheses. A computed tomography scan can detect foreign bodies, locate perforations, and guide treatment. The findings that suggest perforation are thickening of the intestinal walls, increased mesenteric fat density, and, less frequently, gas in the peritoneal cavity, often restricted to the point of perforation.

  12. Loss of HLTF function promotes intestinal carcinogenesis

    Directory of Open Access Journals (Sweden)

    Sandhu Sumit

    2012-03-01

    Full Text Available Abstract Background HLTF (Helicase-like Transcription Factor is a DNA helicase protein homologous to the SWI/SNF family involved in the maintenance of genomic stability and the regulation of gene expression. HLTF has also been found to be frequently inactivated by promoter hypermethylation in human colon cancers. Whether this epigenetic event is required for intestinal carcinogenesis is unknown. Results To address the role of loss of HLTF function in the development of intestinal cancer, we generated Hltf deficient mice. These mutant mice showed normal development, and did not develop intestinal tumors, indicating that loss of Hltf function by itself is insufficient to induce the formation of intestinal cancer. On the Apcmin/+ mutant background, Hltf- deficiency was found to significantly increase the formation of intestinal adenocarcinoma and colon cancers. Cytogenetic analysis of colon tumor cells from Hltf -/-/Apcmin/+ mice revealed a high incidence of gross chromosomal instabilities, including Robertsonian fusions, chromosomal fragments and aneuploidy. None of these genetic alterations were observed in the colon tumor cells derived from Apcmin/+ mice. Increased tumor growth and genomic instability was also demonstrated in HCT116 human colon cancer cells in which HLTF expression was significantly decreased. Conclusion Taken together, our results demonstrate that loss of HLTF function promotes the malignant transformation of intestinal or colonic adenomas to carcinomas by inducing genomic instability. Our findings highly suggest that epigenetic inactivation of HLTF, as found in most human colon cancers, could play an important role in the progression of colon tumors to malignant cancer.

  13. Intestinal perforation by an ingested foreign body

    Energy Technology Data Exchange (ETDEWEB)

    Nicolodi, Gabriel Cleve; Trippia, Cesar Rodrigo; Caboclo, Maria Fernanda F.S.; Castro, Francisco Gomes de; Miller, Wagner Peitl; Lima, Raphael Rodrigues de; Tazima, Leandro; Geraldo, Jamylle, E-mail: gabrielnicolodi@gmail.com [Hospital Sao Vicente - Funef, Curitiba, PR (Brazil)

    2016-09-15

    Objective: To identify the computed tomography findings suggestive of intestinal perforation by an ingested foreign body. Materials and Methods: This was a retrospective study of four cases of surgically proven intestinal perforation by a foreign body, comparing the computed tomography findings with those described in the literature. Results: None of the patients reported having ingested a foreign body, all were over 60 years of age, three of the four patients used a dental prosthesis, and all of the foreign bodies were elongated and sharp. In all four patients, there were findings indicative of acute abdomen. None of the foreign bodies were identified on conventional X-rays. The computed tomography findings suggestive of perforation were thickening of the intestinal walls (in all four cases), increased density of mesenteric fat (in all four cases), identification of the foreign body passing through the intestinal wall (in three cases), and gas in the peritoneal cavity (in one case). Conclusion: In cases of foreign body ingestion, intestinal perforation is more common when the foreign body is elongated and sharp. Although patients typically do not report having ingested such foreign bodies, the scenario should be suspected in elderly individuals who use dental prostheses. A computed tomography scan can detect foreign bodies, locate perforations, and guide treatment. The findings that suggest perforation are thickening of the intestinal walls, increased mesenteric fat density, and, less frequently, gas in the peritoneal cavity, often restricted to the point of perforation. (author)

  14. The intestinal microbiome of fish under starvation.

    Science.gov (United States)

    Xia, Jun Hong; Lin, Grace; Fu, Gui Hong; Wan, Zi Yi; Lee, May; Wang, Le; Liu, Xiao Jun; Yue, Gen Hua

    2014-04-05

    Starvation not only affects the nutritional and health status of the animals, but also the microbial composition in the host's intestine. Next-generation sequencing provides a unique opportunity to explore gut microbial communities and their interactions with hosts. However, studies on gut microbiomes have been conducted predominantly in humans and land animals. Not much is known on gut microbiomes of aquatic animals and their changes under changing environmental conditions. To address this shortcoming, we determined the microbial gene catalogue, and investigated changes in the microbial composition and host-microbe interactions in the intestine of Asian seabass in response to starvation. We found 33 phyla, 66 classes, 130 orders and 278 families in the intestinal microbiome. Proteobacteria (48.8%), Firmicutes (15.3%) and Bacteroidetes (8.2%) were the three most abundant bacteria taxa. Comparative analyses of the microbiome revealed shifts in bacteria communities, with dramatic enrichment of Bacteroidetes, but significant depletion of Betaproteobacteria in starved intestines. In addition, significant differences in clusters of orthologous groups (COG) functional categories and orthologous groups were observed. Genes related to antibiotic activity in the microbiome were significantly enriched in response to starvation, and host genes related to the immune response were generally up-regulated. This study provides the first insights into the fish intestinal microbiome and its changes under starvation. Further detailed study on interactions between intestinal microbiomes and hosts under dynamic conditions will shed new light on how the hosts and microbes respond to the changing environment.

  15. Fecal markers of intestinal inflammation and intestinal permeability are elevated in Parkinson's disease.

    Science.gov (United States)

    Schwiertz, Andreas; Spiegel, Jörg; Dillmann, Ulrich; Grundmann, David; Bürmann, Jan; Faßbender, Klaus; Schäfer, Karl-Herbert; Unger, Marcus M

    2018-02-12

    Intestinal inflammation and increased intestinal permeability (both possibly fueled by dysbiosis) have been suggested to be implicated in the multifactorial pathogenesis of Parkinson's disease (PD). The objective of the current study was to investigate whether fecal markers of inflammation and impaired intestinal barrier function corroborate this pathogenic aspect of PD. In a case-control study, we quantitatively analyzed established fecal markers of intestinal inflammation (calprotectin and lactoferrin) and fecal markers of intestinal permeability (alpha-1-antitrypsin and zonulin) in PD patients (n = 34) and controls (n = 28, group-matched for age) by enzyme-linked immunosorbent assay. The study design controlled for potential confounding factors. Calprotectin, a fecal marker of intestinal inflammation, and two fecal markers of increased intestinal permeability (alpha-1-antitrypsin and zonulin) were significantly elevated in PD patients compared to age-matched controls. Lactoferrin, as a second fecal marker of intestinal inflammation, showed a non-significant trend towards elevated concentrations in PD patients. None of the four fecal markers correlated with disease severity, PD subtype, dopaminergic therapy, or presence of constipation. Fecal markers reflecting intestinal inflammation and increased intestinal permeability have been primarily investigated in inflammatory bowel disease so far. Our data indicate that calprotectin, alpha-1-antitrypsin and zonulin could be useful non-invasive markers in PD as well. Even though these markers are not disease-specific, they corroborate the hypothesis of an intestinal inflammation as contributing factor in the pathogenesis of PD. Further investigations are needed to determine whether calprotectin, alpha-1-antitrypsin and zonulin can be used to define PD subgroups and to monitor the effect of interventions in PD. Copyright © 2018 Elsevier Ltd. All rights reserved.

  16. VENEZUELA EN EL PROCESO DE INCORPORACIÓN AL MERCOSUR

    Directory of Open Access Journals (Sweden)

    Dani José Villalobos Soto

    2012-10-01

    Full Text Available Diversos han sido los esquemas de integración que han experimentado en sus prácticas los países de Latinoamérica, en su lucha por lograr una concentración de esfuerzos frentes a las vicisitudes en aras de alcanzar intereses comunes para la región. Esta investigación enfoca al MERCOSUR como un proceso de integración que busca la conformación de un mercado común por medio de la eliminación de barreras arancelarias y para arancelarias. En ese sentido el presente estudio considera la participación de la República Bolivariana de Venezuela como posible miembro pleno del bloque, también se analiza el escenario asimétrico que caracteriza a Venezuela para su ingreso al MERCOSUR, donde se destacan las asimetrías de Venezuela para con los países miembros del bloque sureño, considerando de esta forma los potenciales beneficios y costos que tendrá para Venezuela la inclusión real al conglomerado de países que integran el MERCOSUR. Se ha basado en un trabajo de tipo documental, donde se realiza un análisis sobre la inclusión de Venezuela al esquema integracionista. Como conclusión es importante destacar que el objetivo de MERCOSUR  se basa en crear una zona de libre comercio para beneficio de los países que integran América del Sur.

  17. Afrontar el proceso de duelo To deal with grief

    Directory of Open Access Journals (Sweden)

    Mª Trinidad Pérez Vallejo

    2008-06-01

    Full Text Available Ana, con su testimonio y con su vida nos enseña como afrontar los procesos de duelo. La muerte de su esposo se produce en febrero de 2005, este suceso fue probablemente la experiencia más difícil e importante que ha pasado durante sus 74 años de vida. Ana cuidó a su esposo durante la enfermedad con celo, dedicación y sobre todo con mucho amor. Ahora nos cuenta su experiencia para que pueda servir a aliviar a todas aquellas personas que se hallan en una situación semejante, a la vez, que rinde homenaje a su esposo que con su vida llena de salud y vitalidad le enseñó a morir. Ana tiene una vida plena dedicada a ayudar a los más necesitados, y canaliza esa ayuda con la gente de su barrio visitando a los enfermos, a los que se encuentran solos y los que tienen condiciones económicas más adversas.Anne, in her testimony and life, teaches us how to deal with grief. The death of her husband, on February, 2005, was probably the most difficult and important occurance in the 74 years of her life. Anne had cared for her husband with zeal, dedication and most importantly, love. Anne shares her experience with us so that it may help to alleviate those of us who find ourselves in a similar situation, and at the same time, pays homage to her husband who, when he was filled whit health and vitality, taught to die. Now Anne has a full life dedicated to helping the most needy as she channels this help through the people of her neighbourhood, visiting the ill, the lonely and those in the most adverse economic circumstances.

  18. El corazón endocrino y el proceso inflamatorio

    Directory of Open Access Journals (Sweden)

    Tsuneo Ogawa

    2013-12-01

    Full Text Available El corazón endocrino, a través de sus hormonas polipéptidas atrial natriuretic factor (ANF o ANP y brain natriuretic peptide (BNP, contribuye a regular la precarga y la poscarga cardiacas. Otras importantes funciones se han descubierto recientemente incluyendo interacciones con el sistema inmunológico. Los niveles plasmáticos de BNP, no así los de ANF, aumentan durante un episodio de rechazo agudo del corazón alotransplantado pero retornan a niveles anteriores al episodio de rechazo después de un tratamiento exitoso del tal rechazo. Este fue el primer indicio que involucró el BNP y el sistema inmunológico. Otras patologías que tienen componentes inflamatorios también se ven acompañadas con cambios en la producción del BNP. El aumento del BNP tiene como base el aumento de la actividad transcripcional del gen inducida por citoquinas y substancias relacionadas. In vitro se puede demostrar que este aumento tiende a modular la actividad inmunológica. Inflamación y cambios hemodinámicos co-existen en la mayoría de las enfermedades cardiovasculares y por ende, es posible que sea beneficioso medir las dos hormonas como biomarcadores de cambios de volumen intravascular (ANF y de estos cambios más inflamación (BNP. Cambios en plasma de ANF relativamente más grandes que aquellos de BNP podrían indicar un deterioro hemodinámico, mientras que cambios importantes en BNP podrían ser indicativos de recrudecimiento del proceso inflamatorio.

  19. SISTEMAS TUTORES INTELIGENTES COMO APOYO EN EL PROCESO DE APRENDIZAJE

    Directory of Open Access Journals (Sweden)

    Edwin Eduardo Millan Rojas

    2015-09-01

    Full Text Available El objetivo principal de este artículo es la identificación de las principales características de los tutores inteligentes, su origen y evolución los cuales pueden ofrecer elementos para la formulación de nuevos proyectos de investigación relacionados con la educación y el uso de los tutores. El método utilizado es el descriptivo y sistémico, los cuales permiten recopilar los datos necesarios, la información presentada ha sido adquirida de bases de datos especializadas como IEEE, Redalyc, ACM y Science Direct, además de artículos de revistas de universidades internacionales y de proyectos de investigación descargados de Google Académico. Los Sistemas Tutores Inteligentes surgieron al combinar técnicas de inteligencia artificial (IA con los métodos clásicos de enseñanza. Estos son sistemas de software que generan un ambiente idóneo para la interacción y satisfacción de las necesidades del estudiante, adaptable a los conocimientos previos y a la capacidad de evolución de cada alumno respecto a un área del conocimiento. El funcionamiento de los STI se basa en la relación entre tres principales módulos (tutor, estudiante y dominio, para presentar al usuario la información de manera estructurada. La investigación llevada a cabo permitió reunir los aspectos más relevantes de los Sistemas Tutores Inteligentes (STI y presentarlos como una herramienta óptima para llevar a cabo un proceso de aprendizaje.

  20. La reforma del proceso penal en España

    Directory of Open Access Journals (Sweden)

    Isabel Hernández Gómez

    2005-01-01

    Full Text Available El presente artículo trata de la reforma de la justicia penal española, comenzada hace casi 20 años, a partir de la llegada de la democracia y de la vigencia del Texto Constitucional de 1978, y que ha sido una reivindicación mayoritaria de la doctrina especializada y de la propia sociedad. Nadie que se aproxime con un mínimo de objetividad a la situación de nuestra justicia criminal puede discrepar de la necesidad de la reforma del sistema que, de manera parcial, se ha llevado a cabo en las últimas iniciativas legislativas modificadoras de la Ley de Enjuiciamiento Criminal, con soluciones técnicas que casi resultan evidentes por sí mismas. Quizá mejor que ninguna otra iniciativa legislativa de cuantas han surgido del Pacto de Estado para la Reforma de la Justicia, la denominada Ley de Juicios Rápidos (Ley 38/2002 de 24 de octubre de Reforma de la Ley de Enjuiciamiento Criminal, y su complementaria la L. O. 8/2002, resume los dos grandes objetivos trazados por el Ministerio de Justicia: Por una parte, modernizar la administración de justicia española, haci éndola más ágil, eficiente, transparente y cercana a los ciudadanos, y por otra, fortalecer el sistema judicial en su conjunto como instrumento básico de la lucha contra la criminalidad. Desde algunos sectores se ha pretendido transmitir a la comunidad jurí- dica que la lentitud en la instrucción penal aporta garantías para el imputado. Sin embargo, entendemos que la tardanza de varias semanas o meses en realizar la instrucción, nada tiene que ver con las garantías procesales inherentes al due process of law, cuyo íntimo valor constitucional (el llamado principio de procedimiento, que construye laboriosamente la doctrina del Tribunal Supremo estadounidense a partir de la XVI Enmienda no debemos pervertir. Tampoco creemos que aporte ninguna ventaja al imputado ni a las víctimas ni a los terceros que hayan de participar en el proceso penal, la prolongación indefinida de

  1. Combinación de procesos de oxidación avanzada y procesos anaerobios para tratamiento de aguas residuales hospitalarias

    OpenAIRE

    , Carlos; Chaparro, Tatiana

    2014-01-01

    Las aguas residuales hospitalarias son una de las principalesfuentes de contaminantes emergentes (e.g. antibióticos,antiepilépticos, hormonas). Debido a la baja eficiencia de los procesos convencionales usados en las plantas de tratamiento de aguas residuales municipales, para eliminar la materia orgánica de este origen, combinar procesos de oxidación avanzada con tratamientos biológicos, surge como una alternativa para reducir el impacto en en el ambiente de estas aguas residuales. Con base ...

  2. Molecular aspects of intestinal calcium absorption.

    Science.gov (United States)

    Diaz de Barboza, Gabriela; Guizzardi, Solange; Tolosa de Talamoni, Nori

    2015-06-21

    Intestinal Ca(2+) absorption is a crucial physiological process for maintaining bone mineralization and Ca(2+) homeostasis. It occurs through the transcellular and paracellular pathways. The first route comprises 3 steps: the entrance of Ca(2+) across the brush border membranes (BBM) of enterocytes through epithelial Ca(2+) channels TRPV6, TRPV5, and Cav1.3; Ca(2+) movement from the BBM to the basolateral membranes by binding proteins with high Ca(2+) affinity (such as CB9k); and Ca(2+) extrusion into the blood. Plasma membrane Ca(2+) ATPase (PMCA1b) and sodium calcium exchanger (NCX1) are mainly involved in the exit of Ca(2+) from enterocytes. A novel molecule, the 4.1R protein, seems to be a partner of PMCA1b, since both molecules co-localize and interact. The paracellular pathway consists of Ca(2+) transport through transmembrane proteins of tight junction structures, such as claudins 2, 12, and 15. There is evidence of crosstalk between the transcellular and paracellular pathways in intestinal Ca(2+) transport. When intestinal oxidative stress is triggered, there is a decrease in the expression of several molecules of both pathways that inhibit intestinal Ca(2+) absorption. Normalization of redox status in the intestine with drugs such as quercetin, ursodeoxycholic acid, or melatonin return intestinal Ca(2+) transport to control values. Calcitriol [1,25(OH)₂D₃] is the major controlling hormone of intestinal Ca(2+) transport. It increases the gene and protein expression of most of the molecules involved in both pathways. PTH, thyroid hormones, estrogens, prolactin, growth hormone, and glucocorticoids apparently also regulate Ca(2+) transport by direct action, indirect mechanism mediated by the increase of renal 1,25(OH)₂D₃ production, or both. Different physiological conditions, such as growth, pregnancy, lactation, and aging, adjust intestinal Ca(2+) absorption according to Ca(2+) demands. Better knowledge of the molecular details of intestinal Ca(2

  3. REQUERIMIENTOS DE ENERGÍA EN LOS PROCESOS DE FABRICACIÓN A NANOESCALA

    Directory of Open Access Journals (Sweden)

    PLACIDO T FERREIRA

    2010-07-01

    Full Text Available En este artículo se describen las principales tecnologías de fabricación a nanoescala, y se examinan cualitativamente los requerimientos, que tienen con respecto a la demanda de energía, sus procesos fundamentales. Estos requerimientos se relacionan con los procesos aplicados en la fabricación de semiconductores; también se describen las falencias en la comprensión de estos procesos para la producción a nanoescala, cuya comunidad investigadora los identifica como objetivos a corto plazo. Por último, se propone un marco para el análisis sistemático del uso de energía en los procesos de fabricación a nanoescala.

  4. La asimilación de conceptos:un modelo basado en procesos cognitivos

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    Pedro Nel Zapata Castañeda

    2012-04-01

    Full Text Available A continuación se presentan los resultados de una investigación realizada sobre los procesos cognitivos implicados en la asimilación, la inclusión y la elaboración de relaciones entre conceptos en el contexto de enseñanza y aprendizaje de la ciencia química. Los resultados muestran una mayor dificultad en el dominio de los procesos cognitivos relacionados con la elaboración de relaciones conceptuales de segundo orden, y señalan la dependencia de dichos procesos respecto a los contenidos a los que se aplica y su independencia respecto a otros procesos cognitivos, que confirman tesis como las de Allport (1980 sobre la especificidad neuronal a patrones específicos de información y el procesamiento de información en paralelo.

  5. Formación Continuada: El proceso cognitivo y el aprendizaje profesional

    Directory of Open Access Journals (Sweden)

    María Nolla Domenjó

    Full Text Available La investigación en educación médica realizada durante las últimas décadas ha contribuido a poder comprender mejor el proceso de aprendizaje.Los docentes deberían conocer los resultados de estos estudios para poder adecuar los programas de formación a la evidencia disponible.En este artículo se pretende hacer un repaso del estado de la cuestión referente al desarrollo profesional de los médicos. Se considera que el proceso de aprendizaje es un proceso constructivista, autodirigido, colaborativo y contextual. Además de los principios del aprendizaje, se trata el proceso de razonamiento clínico y la importancia de la práctica reflexiva durante toda la vida profesional.

  6. La frontera México-Estados Unidos: dinámicas transfronterizas y procesos de gobernanza

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    María del Rosio Barajas Escamilla

    2016-01-01

    Full Text Available Bajo el proceso de la globalización y los procesos de integración regional, los espacios de frontera experimentan importantes cambios en sus funciones y en su escala de influencia. Así lo muestra la reconfiguración de los espacios fronterizos dentro de la Unión Europea, del Mercosur y en cierta medida en el marco del TLCAN. El objetivo particular del estudio es analizar las características que asume la reconfiguración del territorio de frontera entre México con Estados Unidos y sus nuevos procesos de gobernanza, donde los gobiernos multinivel (nivel trilateral, bilateral, federal, estatal, local y transfronterizo y los organismos privados y de la sociedad civil están llamados a jugar un nuevo papel en el proceso de construcción de una región transfronteriza.

  7. Quiste del mesenterio intestinal en la edad pediátrica

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    Ada Arleny Pérez Mayo

    2014-08-01

    Full Text Available Se presenta el caso de una paciente de 9 años de edad, ingresada por molestia abdominal en el Hospital Nacional de San Pedro Necta del Departamento de Huehuetenango, en Guatemala. Constituyó una rara lesión intra-abdominal, que pudo provocar abdomen agudo. Fue interpretado inicialmente como quiste de ovario gigante. La ausencia de ecografía abdominal y la presencia de distensión y masa palpable asintomática decidieron la intervención quirúrgica. Se realizó una cuidadosa preparación preoperatoria, que incluyó la antisepsia local de la piel y la administración de ceftriaxona, como antibiótico profiláctico. Durante la laparotomía exploradora se constató un quiste gigante del mesenterio del intestino delgado, de 17 cm de longitud, localizado a nivel del íleon terminal y sujeto por un pedículo ampliamente vascularizado. La técnica quirúrgica consistió en la exéresis total de la lesión y no se requirió de resección intestinal ante la ausencia de oclusión intestinal. Los hallazgos anatomo-patológicos informaron proceso benigno. No se reportaron complicaciones y la paciente evolucionó satisfactoriamente, reportándose una estadía hospitalaria de cinco días

  8. Intestinal ischemia-reperfusion injury augments intestinal mucosal injury and bacterial translocation in jaundiced rats.

    Science.gov (United States)

    Yüksek, Yunus Nadi; Kologlu, Murat; Daglar, Gül; Doganay, Mutlu; Dolapci, Istar; Bilgihan, Ayse; Dolapçi, Mete; Kama, Nuri Aydin

    2004-01-01

    The aim of this study was to evaluate local effects and degree of bacterial translocation related with intestinal ischemia-reperfusion injury in a rat obstructive jaundice model. Thirty adult Sprague-Dawley rats (200-250 g) were divided into three groups; including Group 1 (jaundice group), Group 2 (jaundice-ischemia group) and Group 3 (ischemia group). All rats had 2 laparotomies. After experimental interventions, tissue samples for translocation; liver and ileum samples for histopathological examination, 25 cm of small intestine for mucosal myeloperoxidase and malondialdehyde levels and blood samples for biochemical analysis were obtained. Jaundiced rats had increased liver enzyme levels and total and direct bilirubin levels (p<0.05). Intestinal mucosal myeloperoxidase and malondialdehyde levels were found to be high in intestinal ischemia-reperfusion groups (p<0.05). Intestinal mucosal damage was more severe in rats with intestinal ischemia-reperfusion after bile duct ligation (p<0.05). Degree of bacterial translocation was also found to be significantly high in these rats (p<0.05). Intestinal mucosa is disturbed more severely in obstructive jaundice with the development of ischemia and reperfusion. Development of intestinal ischemia-reperfusion in obstructive jaundice increases bacterial translocation.

  9. Plasma intestinal fatty acid binding protein (I-FABP) concentrations increase following intestinal ischemia in pigs

    NARCIS (Netherlands)

    Niewold, T.A.; Meinen, M.; Meulen, van der J.

    2004-01-01

    Intestinal fatty acid binding protein (I-FABP) is an intracellular epithelial protein in the intestinal mucosa of many animals. IFABP appears in the circulation following epithelial damage, and in humans, is proven to be a parameter for damage to the mucosa. In this paper, an ELISA test designed for

  10. Intestinal rehabilitation for children with intestinal failure is cost-effective : a simulation study

    NARCIS (Netherlands)

    Groen, Henk; Neelis, Esther G; Poley, Marten J; Olieman, Joanne F; Scheenstra, René; Krabbe, Paul Fm; Dijkstra, Gerard; Rings, Edmond Hhm

    2017-01-01

    BACKGROUND: Children with intestinal failure (IF) depend on parenteral nutrition (PN). The goal in the treatment of IF is to wean children off PN through intestinal rehabilitation (IR). Although the healthcare burden of IF is enormous, to our knowledge there has been no previous cost-effectiveness

  11. Intestinal rehabilitation for children with intestinal failure is cost-effective : a simulation study

    NARCIS (Netherlands)

    Groen, Henk; Neelis, Esther G.; Poley, Marten J.; Olieman, Joanne F.; Scheenstra, Rene; Krabbe, Paul F. M.; Dijkstra, Gerard; Rings, Edmond H. H. M.

    Background: Children with intestinal failure (IF) depend on parenteral nutrition (PN). The goal in the treatment of IF is to wean children off PN through intestinal rehabilitation (IR). Although the healthcare burden of IF is enormous, to our knowledge there has been no previous cost-effectiveness

  12. [Myosin B ATPase activity of the intestinal smooth muscle in intestinal obstruction].

    Science.gov (United States)

    Takamatsu, H

    1983-06-01

    Intestinal smooth myosin B was prepared from muscle layers around the lesion in dogs with experimental colonic stenosis and in patients with congenital intestinal obstruction. Mg2+-ATPase activity of the myosin B was compared between the proximal dilated segment and distal segment to obstruction. Experimental colonic stenosis: In early period after surgery, proximal colons showed higher activity of myosin B ATPase than distal colons, decreasing to less than distal colon as time passed. Congenital intestinal obstruction: In three cases, whose atresia might have occurred at earlier period of gestation, proximal bowels showed less activity of myosin B ATPase than distal bowels. However, in two cases, whose atresia might have occurred at later period of gestation, and two cases with intestinal stenosis, proximal bowels indicated higher activity of myosin B ATPase than distal bowels. These data suggested that the contractibility of the proximal intestine was depending on the duration of obstruction, and it was depressed in the former patients and was accelerated in the latter patients. These results suggested that the extensive resection of dilated proximal bowel in the congenital atresia is not always necessary to obtain good postoperative intestinal dynamics at the operation of the atresial lesions which may be induced at later period of gestation. They also suggested that surgery for intestinal obstruction should be performed before the depression of intestinal contractibility to get good bowel function.

  13. Habilidades sociales relacionadas con el proceso de comunicación en una muestra de adolescentes

    OpenAIRE

    Betancourth, Sonia; Zambrano, Christian; Ceballos, Ana Karen; Benavides, Vanessa; Villota, Nixon

    2017-01-01

    ResumenLas habilidades sociales son repertorios de comportamientos que los seres humanos utilizan para enfrentar diferentes situaciones de su vida, así como para establecer relaciones interpersonales de calidad. El objetivo del presente estudio es describir las habilidades sociales relacionadas con el proceso de comunicación en estudiantes de grado décimo, de un colegio ubicado en el sur occidente Colombiano, a través de la Escala Habilidades Sociales Relacionadas con el proceso de comunicaci...

  14. Relevancia e Inferencia: Procesos cognitivos propios de la comunicación humana

    Directory of Open Access Journals (Sweden)

    Moya Pardo Constanza

    2006-06-01

    Full Text Available Este artículo pretende mostrar los planteamientos cognitivos más representativos de la Teoría de la Relevancia propuesta por Spelber & Wilson con respecto al modelo ostensivoinferencial. Este modelo plantea un mecanismo deductivo explícito que da cuenta de los procesos y estrategias que permiten el paso del significado literal a la interpretación pragmática de los mensajes en el proceso de comunicación humana.

  15. Organización de la seguridad en el proceso constructivo

    Directory of Open Access Journals (Sweden)

    Mínguez Fernández, César

    1993-02-01

    Full Text Available Thorough and complex study on the implementation of prevention processes and labour safety in the production process in Industrial Construction Companies.

    Profundo y complejo estudio sobre la implantación de los procesos de prevención y salud laboral, en el proceso de producción, en la Empresa Industrial de Construcción.

  16. Importancia de la actividad y la comunicación en el proceso docente - educativo

    OpenAIRE

    Mestre Gómez, Ulises

    2005-01-01

    Un aspecto que contribuye al logro de los objetivos de cualquier proceso educativo es el establecimiento de un clima afectivo entre docente y discente. La creación de tal ambiente de depende, en gran medida, del nivel de comunicación que se consiga imprimir a las relaciones profesor – alumno. En el trabajo se analiza el proceso docente – educativo a la luz de las Teorías de la Actividad y la Comunicación

  17. Hacerse cantaor: un proceso de socialización al mundo del flamenco.

    Directory of Open Access Journals (Sweden)

    Eve Brenel

    2006-01-01

    Full Text Available Este artículo analiza el proceso de aprendizaje y de profesionalización de los cantaores profesionales, cuyas principales vías (complementarias son: el estudio de discos, los contextos privados y el escenario. Lejos del tópico según el cual el cante no se aprende, Eve Brenel demuestra como hacerse cantaor profesional requiere un proceso de socialización al mundo flamenco y a su cultura.

  18. Estudio Fotográfico de Procesos de Corrosión

    OpenAIRE

    Poce Fatou, Juan Antonio

    2012-01-01

    El documento incluye 8 ejercicios de utilidad en el estudio de procesos de corrosión de hierro bajo distintas condiciones. La experiencia básica consiste en un clavo de hierro inmerso en una matriz de agar que contiene ferricianuro potásico y fenolftaleína para identificar las regiones anódicas y catódicas del proceso.

  19. Coagulation of sheep intestinal and prefemoral lymph.

    Science.gov (United States)

    Hanley, C A; Johnston, M G; Nelson, W

    1988-06-01

    We have determined the most suitable method for the automated analysis of the clotting parameters in sheep intestinal and prefemoral lymph as defined by the Activated Partial Thromboplastin Times (APTT; measure of intrinsic coagulation pathway) and the Prothrombin Times (PT; measure of extrinsic coagulation pathway). As opposed to optical density systems, the use of a Fibro-System Fibrometer was found to provide the most consistent assessment of coagulation with the endpoint being the time to fibrin strand formation. We measured APTT in sheep intestinal and prefemoral lymph of 59.78 +/- 7.69 seconds and 51.03 +/- 10.49 seconds respectively. These values were more prolonged than those obtained from sheep blood plasma but only in the case of intestinal lymph were the differences significant (p less than 0.025). Human blood APTT values were significantly less than both sheep blood (p less than 0.05) and sheep intestinal (p less than 0.001) and prefemoral lymph (p less than 0.01). PT values were found to be 21.56 +/- 1.14 seconds in intestinal and 22.00 +/- 1.88 seconds in prefemoral lymph. These values were also significantly greater than those obtained from sheep blood (both p less than 0.001). Human blood PTs were significantly less than both sheep blood (p less than 0.001) and intestinal and prefemoral lymph (both p less than 0.001). Measurement of APTT and PT values in intestinal lymph and PT determinations in prefemoral lymph were not affected by storage in the refrigerator or freezer. There was some indication that APTT values in prefemoral samples were susceptible to storage artifacts; however, the differences in coagulation times were not significant.

  20. Neonatal intestinal obstruction in Benin, Nigeria

    Directory of Open Access Journals (Sweden)

    Osifo Osarumwense

    2009-01-01

    Full Text Available Background: Intestinal obstruction is a life threatening condition in the newborn, with attendant high mortality rate especially in underserved subregion. This study reports the aetiology, presentation, and outcome of intestinal obstruction management in neonates. Materials and Methods: A prospective study of neonatal intestinal obstruction at the University of Benin Teaching Hospital, Benin, Nigeria, between January 2006-June 2008. Data were collated on a structured proforma and analysed for age, sex, weight, presentation, type/date of gestation/delivery, aetiology, clinical presentation, associated anomaly, treatment, and outcome. Results: There were 71 neonates, 52 were males and 19 were females (2.7:1. Their age range was between 12 hours and 28 days (mean, 7.9 ± 2.7 days and they weighed between 1.8 and 5.2 kg (average, 3.2 kg. The causes of intestinal obstruction were: Anorectal anomaly, 28 (39.4%; Hirschsprung′s disease, 8 (11.3%′ prematurity, 3 (4.2%; meconeum plug, 2 (2.8%; malrotation, 6 (8.5%; intestinal atresia, 8 (11.3%; necrotising enterocolitis (NEC, 4 (5.6%; obstructed hernia, 4 (5.6%; and spontaneous gut perforation, 3 (4.2%. Also, 27 (38% children had colostomy, 24 (33.8% had laparotomy, 9 (12.8% had anoplasty, while 11 (15.4% were managed nonoperatively. A total of 41 (57.7% neonates required incubator, 26 (36.6% needed total parenteral nutrition, while 15 (21.1% require d paediatric ventilator. Financial constraint, late presentation, presence of multiple anomalies, aspiration, sepsis, gut perforation, and bowel gangrene were the main contributors to death. Neonates with lower obstructions had a better outcome compared to those having upper intestinal obstruction ( P < 0.0001. Conclusion: Outcomes of intestinal obstruction are still poor in our setting; late presentation, financial constraints, poor parental motivation and lack of basic facilities were the major determinants of mortality.

  1. CT evaluation of mechanical intestinal obstruction

    Energy Technology Data Exchange (ETDEWEB)

    Han, Sung Tag; Kim, Ho Kyun; Jeon, Jeong Dong; Kim, Young Tong [Gollege of Medicine, Inje University, Seoul (Korea, Republic of)

    1994-11-15

    To evaluate the usefulness of CT for the diagnosis and treatment planning of mechanical intestinal obstruction. We retrospectively reviewed 38 patients who were clinically suspected of mechanical intestinal obstruction and had undergone abdominal CT. The CT scans were evaluated for the absence or presence, severity, cause and site of intestinal obstruction. CT findings were compared with the results of laparotomy, barium study and clinical course. The absence or presence and severity of intestinal obstruction were classified into no obstruction, partial obstruction, complete obstruction. Diagnosis was established by means of laparotomy in 20 cases, barium study in 9 cases and clinical course in 9 cases. Of 38 cases, 7(18.4%) showed no obstruction, 22(57.9%) showed partial obstruction, and 9(23.7%) showed complete obstruction. The presence or absence and severity on CT scans were correctly predicted in 36 of 38 cases (sensitivity 95 %, specificity 97 %, accuracy 96 %) (in case of no obstruction: sensitivity 100 %, specificity 94%, accuracy 95%; in case of partial obstruction : sensitivity 91%, specificity 100%, accuracy 95%; in case of complete obstruction : sensitivity 100%, specificity 100%, accuracy 100%). All 9 cases with complete obstruction underwent prompt and immediate laparotomy. 13 cases, excluding those with mass around the site of transition and adhesion with strangulation, with partial obstruction improved with conservative treatment without laparotomy. The causes of obstruction were adhesion in 13, hernia in 6, primary cancer in 5, metastatic cancer in 3, abscess in 2, intestinal tbc in 1, and Crohn's disease in 1. The cause of obstruction on CT scans were correctly predicted in 27 of 31 cases (87.1 %). The sites of obstruction on CT scans were correctly predicted in 22 of 26 cases (84.6%). CT is valuable in the evaluation of absence or presence, severity, cause and site of intestinal obstruction, and is considered to be helpful in treatment

  2. El proceso de transformación de Real Madrid en marca corporativa

    Directory of Open Access Journals (Sweden)

    Luis MAÑAS-VINIEGRA

    2018-01-01

    Full Text Available Esta investigación tiene como objetivo analizar la marca Real Madrid como marca reputada, su globalización y valor añadido emocional, contemplando todas las variables que intervienen en su proceso evolutivo desde una estrategia de marca producto hacia otra de marca corporativa. El estudio de caso y las entrevistas semiestructuradas a expertos permiten explicar cómo el proceso de globalización llevado a cabo por Real Madrid con anterioridad a otros clubes de fútbol ha sido determinante para refrendar el éxito de su producto (victorias deportivas, sus valores corporativos, la gestión de la organización y sus públicos. De este modo, se ha favorecido un proceso de transformación hacia la marca corporativa y las variables que integran su valor de marca se han nutrido de todo este proceso. El proceso de transformación de Real Madrid en marca corporativa se estructura y jerarquiza en un mapa estratégico que permitirá afrontar la gestión de la marca en el siglo XXI y consolida su posición de lovemark viable con una sólida reputación presente en todo el proceso, que comienza con el desarrollo de un patrimonio simbólico y emocional generado a partir de mediados del siglo XX.

  3. Desafíos educativos en tiempos de auto-comunicación masiva: la interlocución de las audiencias Educational Challenges in Times of Mass Self-communication: A Dialogue among Audience

    Directory of Open Access Journals (Sweden)

    Agustín García Matilla

    2012-03-01

    Full Text Available En este texto se abordan esencialmente dos temas. En primer lugar, los cambios emergentes en el estar como audiencias frente a nuevos y viejos medios y, en segundo lugar, los procesos múltiples de recepción e interlocución que hoy experimentan. Se argumenta que las audiencias sin perder siempre ese rol, están también asumiendo otros más activos e interactuando cada vez más como noveles productores y emisores de contenidos mediáticos, similares a los que intercambian a través de diversos lenguajes, formatos y dispositivos tecnológicos. Se destaca la necesidad de diferenciar el consumo amplificado y la gran conectividad existente, de una auténtica interlocución horizontal, creativa y propositiva de los interlocutores. Por otra parte, se presenta una propuesta educomunicativa acorde con esta realidad polimorfa y cambiante de las audiencias, que rescata la tradición pedagógico-crítica iberoamericana y que se desarrolla en la Universidad de Valladolid, Campus de Segovia. La asignatura «Comunicación, educación y sociedad en el contexto digital» se programa en los estudios de Comunicación de esta Universidad con el objetivo de desarrollar y fortalecer aquellas capacidades, destrezas y reflexiones apropiadas para una interlocución más integral en el mundo de la educomunicación. El principal objetivo de la educación en competencia comunicativa, educación en medios y alfabetización digital es educar en las técnicas y estrategias para el análisis y producción de contenidos en medios. En este artículo se subraya la gran complejidad comunicativa y cultural que conllevan los esfuerzos educativos en esta dirección.This text is an approach on two leading topics: the changes emerging in the way audiences deal with new and old media, and, the multiple processes of reception and interaction occurring as a result of the information and communication systems. Audiences are seemingly devising new roles as creators and emitters of media

  4. Intestinal cytochromes P450 regulating the intestinal microbiota and its probiotic profile

    Directory of Open Access Journals (Sweden)

    Eugenia Elefterios Venizelos Bezirtzoglou

    2012-09-01

    Full Text Available Cytochromes P450 (CYPs enzymes metabolize a large variety of xenobiotic substances. In this vein, a plethora of studies were conducted to investigate their role, as cytochromes are located in both liver and intestinal tissues. The P450 profile of the human intestine has not been fully characterized. Human intestine serves primarily as an absorptive organ for nutrients, although it has also the ability to metabolize drugs. CYPs are responsible for the majority of phase I drug metabolism reactions. CYP3A represents the major intestinal CYP (80% followed by CYP2C9. CYP1A is expressed at high level in the duodenum, together with less abundant levels of CYP2C8-10 and CYP2D6. Cytochromes present a genetic polymorphism intra- or interindividual and intra- or interethnic. Changes in the pharmacokinetic profile of the drug are associated with increased toxicity due to reduced metabolism, altered efficacy of the drug, increased production of toxic metabolites, and adverse drug interaction. The high metabolic capacity of the intestinal flora is due to its enormous pool of enzymes, which catalyzes reactions in phase I and phase II drug metabolism. Compromised intestinal barrier conditions, when rupture of the intestinal integrity occurs, could increase passive paracellular absorption. It is clear that high microbial intestinal charge following intestinal disturbances, ageing, environment, or food-associated ailments leads to the microbial metabolism of a drug before absorption. The effect of certain bacteria having a benefic action on the intestinal ecosystem has been largely discussed during the past few years by many authors. The aim of the probiotic approach is to repair the deficiencies in the gut flora and establish a protective effect. There is a tentative multifactorial association of the CYP (P450 cytochrome role in the different diseases states, environmental toxic effects or chemical exposures and nutritional status.

  5. Generation of tissue-engineered small intestine using embryonic stem cell-derived human intestinal organoids.

    Science.gov (United States)

    Finkbeiner, Stacy R; Freeman, Jennifer J; Wieck, Minna M; El-Nachef, Wael; Altheim, Christopher H; Tsai, Yu-Hwai; Huang, Sha; Dyal, Rachel; White, Eric S; Grikscheit, Tracy C; Teitelbaum, Daniel H; Spence, Jason R

    2015-10-12

    Short bowel syndrome (SBS) is characterized by poor nutrient absorption due to a deficit of healthy intestine. Current treatment practices rely on providing supportive medical therapy with parenteral nutrition; while life saving, such interventions are not curative and are still associated with significant co-morbidities. As approaches to lengthen remaining intestinal tissue have been met with only limited success and intestinal transplants have poor survival outcomes, new approaches to treating SBS are necessary. Human intestine derived from embryonic stem cells (hESCs) or induced pluripotent stem cells (iPSCs), called human intestinal organoids (HIOs), have the potential to offer a personalized and scalable source of intestine for regenerative therapies. However, given that HIOs are small three-dimensional structures grown in vitro, methods to generate usable HIO-derived constructs are needed. We investigated the ability of hESCs or HIOs to populate acellular porcine intestinal matrices and artificial polyglycolic/poly L lactic acid (PGA/PLLA) scaffolds, and examined the ability of matrix/scaffolds to thrive when transplanted in vivo. Our results demonstrate that the acellular matrix alone is not sufficient to instruct hESC differentiation towards an endodermal or intestinal fate. We observed that while HIOs reseed acellular porcine matrices in vitro, the HIO-reseeded matrices do not thrive when transplanted in vivo. In contrast, HIO-seeded PGA/PLLA scaffolds thrive in vivo and develop into tissue that looks nearly identical to adult human intestinal tissue. Our results suggest that HIO-seeded PGA/PLLA scaffolds are a promising avenue for developing the mucosal component of tissue engineered human small intestine, which need to be explored further to develop them into fully functional tissue. © 2015. Published by The Company of Biologists Ltd.

  6. Generation of tissue-engineered small intestine using embryonic stem cell-derived human intestinal organoids

    Directory of Open Access Journals (Sweden)

    Stacy R. Finkbeiner

    2015-11-01

    Full Text Available Short bowel syndrome (SBS is characterized by poor nutrient absorption due to a deficit of healthy intestine. Current treatment practices rely on providing supportive medical therapy with parenteral nutrition; while life saving, such interventions are not curative and are still associated with significant co-morbidities. As approaches to lengthen remaining intestinal tissue have been met with only limited success and intestinal transplants have poor survival outcomes, new approaches to treating SBS are necessary. Human intestine derived from embryonic stem cells (hESCs or induced pluripotent stem cells (iPSCs, called human intestinal organoids (HIOs, have the potential to offer a personalized and scalable source of intestine for regenerative therapies. However, given that HIOs are small three-dimensional structures grown in vitro, methods to generate usable HIO-derived constructs are needed. We investigated the ability of hESCs or HIOs to populate acellular porcine intestinal matrices and artificial polyglycolic/poly L lactic acid (PGA/PLLA scaffolds, and examined the ability of matrix/scaffolds to thrive when transplanted in vivo. Our results demonstrate that the acellular matrix alone is not sufficient to instruct hESC differentiation towards an endodermal or intestinal fate. We observed that while HIOs reseed acellular porcine matrices in vitro, the HIO-reseeded matrices do not thrive when transplanted in vivo. In contrast, HIO-seeded PGA/PLLA scaffolds thrive in vivo and develop into tissue that looks nearly identical to adult human intestinal tissue. Our results suggest that HIO-seeded PGA/PLLA scaffolds are a promising avenue for developing the mucosal component of tissue engineered human small intestine, which need to be explored further to develop them into fully functional tissue.

  7. Intestinal Leiomyositis: A Cause of Chronic Intestinal Pseudo-Obstruction in 6 Dogs.

    Science.gov (United States)

    Zacuto, A C; Pesavento, P A; Hill, S; McAlister, A; Rosenthal, K; Cherbinsky, O; Marks, S L

    2016-01-01

    Intestinal leiomyositis is a suspected autoimmune disorder affecting the muscularis propria layer of the gastrointestinal tract and is a cause of chronic intestinal pseudo-obstruction in humans and animals. To characterize the clinical presentation, histopathologic features, and outcome of dogs with intestinal leiomyositis in an effort to optimize treatment and prognosis. Six client-owned dogs. Retrospective case series. Medical records were reviewed to describe signalment, clinicopathologic and imaging findings, histopathologic diagnoses, treatment, and outcome. All biopsy specimens were reviewed by a board-certified pathologist. Median age of dogs was 5.4 years (range, 15 months-9 years). Consistent clinical signs included vomiting (6/6), regurgitation (2/6), and small bowel diarrhea (3/6). Median duration of clinical signs before presentation was 13 days (range, 5-150 days). Diagnostic imaging showed marked gastric distension with dilated small intestines in 4/6 dogs. Full-thickness intestinal biopsies were obtained in all dogs by laparotomy. Histopathology of the stomach and intestines disclosed mononuclear inflammation, myofiber degeneration and necrosis, and fibrosis centered within the region of myofiber loss in the intestinal muscularis propria. All dogs received various combinations of immunomodulatory and prokinetic treatment, antimicrobial agents, antiemetics, and IV fluids, but none of the dogs showed a clinically relevant improvement with treatment. Median survival was 19 days after diagnosis (range, 3-270 days). Intestinal leiomyositis is a cause of intestinal pseudo-obstruction and must be diagnosed by full-thickness intestinal biopsy. This disease should be considered in dogs with acute and chronic vomiting, regurgitation, and small bowel diarrhea. Copyright © 2015 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine.

  8. Intestinal parasitic infections in renal transplant recipients.

    Science.gov (United States)

    Azami, Mehdi; Sharifi, Mehran; Hejazi, Sayed Hossein; Tazhibi, Mehdi

    2010-01-01

    The impact of intestinal parasitic infection in renal transplant recipients requires careful consideration in the developing world. However, there have been very few studies addressing this issue in Iran. This study was conducted to determine the prevalence of intestinal parasitic infections in renal transplant recipients in Iran. Stool specimens from renal transplant recipients and control groups were obtained between June 2006 and January 2007. The samples screened for intestinal parasitic infections using direct smear, formalin-ether sedimentation, Sheather's flotation and modified Ziehl-Neelsen staining methods. Out of 150 renal transplant recipients, 33.3% (50), and out of 225 control group, 20% (45) were infected with one or more type of intestinal parasites. The parasites detected among patients included Entamoeba coli (10.6%), Endolimax nana (8.7%), Giardia lamblia (7.4%), Blastocystis spp. (4.7%), Iodamoeba butschlii (0.7%), Chilomastix mesnili (0.7%) and Ascaris lumbricoides (0.7%). Multiple infections were more common among renal transplant recipients group (p < 0.05). This study highlights the importance of testing for intestinal parasites among Iranian renal transplant recipients. Routine examinations of stool samples for parasites would significantly benefit the renal transplant recipients by contributing to reduce severe infections.

  9. Macrophages in intestinal homeostasis and inflammation

    Science.gov (United States)

    Bain, Calum C; Mowat, Allan McI

    2014-01-01

    The intestine contains the largest pool of macrophages in the body which are essential for maintaining mucosal homeostasis in the face of the microbiota and the constant need for epithelial renewal but are also important components of protective immunity and are involved in the pathology of inflammatory bowel disease (IBD). However, defining the biological roles of intestinal macrophages has been impeded by problems in defining the phenotype and origins of different populations of myeloid cells in the mucosa. Here, we discuss how multiple parameters can be used in combination to discriminate between functionally distinct myeloid cells and discuss the roles of macrophages during homeostasis and how these may change when inflammation ensues. We also discuss the evidence that intestinal macrophages do not fit the current paradigm that tissue-resident macrophages are derived from embryonic precursors that self-renew in situ, but require constant replenishment by blood monocytes. We describe our recent work demonstrating that classical monocytes constantly enter the intestinal mucosa and how the environment dictates their subsequent fate. We believe that understanding the factors that drive intestinal macrophage development in the steady state and how these may change in response to pathogens or inflammation could provide important insights into the treatment of IBD. PMID:24942685

  10. Glutamine and Its Effects on the Intestine

    Directory of Open Access Journals (Sweden)

    Paul E Hardy

    1991-01-01

    Full Text Available Glutamine, an amino acid, is the principal energy substrate for small intestinal cells. It also acts as a nitrogen carrier through its amide nitrogen. Arterial glutamine is supported by net synthesis in skeletal muscle. Glutamine is rapidly metabolized by the intestine, whether supplied from the lumen or from the arterial circulation. Intestinal uptake of glutamine increases after trauma and operative stress. The consumption of glutamine by the gut may in large part be dependent on mucosal glutaminase activity and on enterocyte glutamine transport. Glutaminc has been shown to improve gut morphology and outcome in animal models of encerocolitis. It may play a similar role in aiding repair of human intestinal injury in persons with sufficient glutamine in their diet compared to those who arc glutamine deficient. Glutamine may have a positive effect on the immune function of the intestinal mucosal-associated lymphoid tissue. Glutamine is not currently available in nutritional preparations for routine clinical use, yet it has recently been shown to benefit maintenance of nitrogen balance in humans. Due to the instability and low solubility of glutamine, dipeptides have been studied. L-alanyl-L-glutamine seems to be the most promising glutamine precursor for parenteral use in humans, as it is safe and rapidly hydrolyzed in vivo to release free glutamine. The exact role of glutamine as a therapeutic agent to promote intetitinal well-being has yet to be determined. However, preliminary evidence suggests that glutaminc will be helpful in a variety of clinical scenarios.

  11. Intestinal parasitic infections in renal transplant recipients

    Directory of Open Access Journals (Sweden)

    Mehdi Azami

    Full Text Available The impact of intestinal parasitic infection in renal transplant recipients requires careful consideration in the developing world. However, there have been very few studies addressing this issue in Iran. This study was conducted to determine the prevalence of intestinal parasitic infections in renal transplant recipients in Iran. Stool specimens from renal transplant recipients and control groups were obtained between June 2006 and January 2007. The samples screened for intestinal parasitic infections using direct smear, formalin-ether sedimentation, Sheather's flotation and modified Ziehl-Neelsen staining methods. Out of 150 renal transplant recipients, 33.3% (50, and out of 225 control group, 20% (45 were infected with one or more type of intestinal parasites. The parasites detected among patients included Entamoeba coli (10.6%, Endolimax nana (8.7%, Giardia lamblia (7.4%, Blastocystis spp. (4.7%, Iodamoeba butschlii (0.7%, Chilomastix mesnili (0.7% and Ascaris lumbricoides (0.7%. Multiple infections were more common among renal transplant recipients group (p < 0.05. This study highlights the importance of testing for intestinal parasites among Iranian renal transplant recipients. Routine examinations of stool samples for parasites would significantly benefit the renal transplant recipients by contributing to reduce severe infections.

  12. Small Intestinal Obstruction Caused by Anisakiasis

    Directory of Open Access Journals (Sweden)

    Yuichi Takano

    2013-01-01

    Full Text Available Small intestinal anisakiasis is a rare disease that is very difficult to diagnose, and its initial diagnosis is often surgical. However, it is typically a benign disease that resolves with conservative treatment, and unnecessary surgery can be avoided if it is appropriately diagnosed. This case report is an example of small intestinal obstruction caused by anisakiasis that resolved with conservative treatment. A 63-year-old man admitted to our department with acute abdominal pain. A history of raw fish (sushi ingestion was recorded. Abdominal CT demonstrated small intestinal dilatation with wall thickening and contrast enhancement. Ascitic fluid was found on the liver surface and in the Douglas pouch. His IgE (RIST was elevated, and he tested positive for the anti-Anisakis antibodies IgG and IgA. Small intestinal obstruction by anisakiasis was highly suspected and conservative treatment was performed, ileus tube, fasting, and fluid replacement. Symptoms quickly resolved, and he was discharged on the seventh day of admission. Small intestinal anisakiasis is a relatively uncommon disease, the diagnosis of which may be difficult. Because it is a self-limiting disease that usually resolves in 1-2 weeks, a conservative approach is advisable to avoid unnecessary surgery.

  13. Tissue response after radiation exposure. Intestine

    International Nuclear Information System (INIS)

    Otsuka, Kensuke; Tomita, Masanori; Yamauchi, Motohiro; Iwasaki, Toshiyasu

    2014-01-01

    Gastrointestinal syndrome followed by 'gut death' is due to intestinal disorders. This syndrome is induced by high-dose (>10 Gy) of ionizing radiation. Recovery from the gastrointestinal syndrome would depend on the number of survived clonogens and regeneration capability of crypts. These tissue alterations can be observed by high-dose radiation, however, cellular dynamics in crypts can be affected by low-dose radiation. For example, Potten et al. found that low-dose radiation induce apoptosis of intestinal stem cells, which produce all differentiated function cells. Recently, intestinal stem cells are characterized by molecular markers such as Lgr5. Since intestinal adenomas can be induced by deletion of Apc gene in Lgr5 + stem cells, it is widely recognized that Lgr5 + stem cells are the cell-of-origin of cancer. Duodenal Lgr5 + stem cells are known as radioresistant cells, however, we found that ionizing radiation significantly induces the turnover of colonic Lgr5 + stem cells. Combined with the knowledge of other radioresistant markers, stem-cell dynamics in tissue after irradiation are becoming clear. The present review introduces the history of gastrointestinal syndrome and intestinal stem cells, and discusses those future perspectives. (author)

  14. Intestinal endocrine cells in radiation enteritis

    International Nuclear Information System (INIS)

    Pietroletti, R.; Blaauwgeers, J.L.; Taat, C.W.; Simi, M.; Brummelkamp, W.H.; Becker, A.E.

    1989-01-01

    In this study, the intestinal endocrine cells were investigated in 13 surgical specimens affected by radiation enteritis. Endocrine cells were studied by means of Grimelius' silver staining and immunostaining for chromogranin, a general marker of endocrine cells. Positively stained cells were quantified by counting their number per unit length of muscularis mucosa. Results in radiation enteritis were compared with matched control specimens by using Student's t test. Chromogranin immunostaining showed a statistically significant increase of endocrine cells in radiation enteritis specimens compared with controls both in small and large intestine (ileum, 67.5 +/- 23.5 cells per unit length of muscularis mucosa in radiation enteritis versus 17.0 +/- 6.1 in controls; colon, 40.9 +/- 13.7 cells per unit length of muscularis mucosa in radiation enteritis versus 9.5 +/- 4.1 in controls--p less than 0.005 in both instances). Increase of endocrine cells was demonstrated also by Grimelius' staining; however, without reaching statistical significance. It is not clear whether or not the increase of endocrine cells in radiation enteritis reported in this study is caused by a hyperplastic response or by a sparing phenomenon. We should consider that increased endocrine cells, when abnormally secreting their products, may be involved in some of the clinical features of radiation enteropathy. In addition, as intestinal endocrine cells produce trophic substances to the intestine, their increase could be responsible for the raised risk of developing carcinoma of the intestine in long standing radiation enteritis

  15. Política 2.0. La comunicación política mediada por Twitter: ¿alternativa o complemento de los medios de comunicación masiva tradicionales? : Estudio de la comunicación política y de sus repercusiones mediáticas centrado en la figura de la Presidenta Cristina Fernández de Kirchner, en el período agosto-octubre de 2011

    OpenAIRE

    Domínguez, Natalia

    2015-01-01

    La presente investigación analizará el uso político de la comunicación 2.0, específicamente de la red de microblogging Twitter. El actor político elegido es la Presidenta de la Nación, Cristina Fernández de Kirchner durante el período agosto de 2011 y octubre de 2011 . Se realizará un análisis sobreconstrucción de la subjetividad política en las redes sociales, las concepciones sobre: la comunicación masiva, el uso de las redes sociales, los debates políticos y la interacción con los usuari...

  16. Measures to minimize small intestine injury in the irradiated pelvis

    International Nuclear Information System (INIS)

    Green, N.; Iba, G.; Smith, W.R.

    1975-01-01

    Small intestine injury causes long-term suffering and high mortality. Five of 187 of our patients had developed serious small intestine injury. Four patients had corrective surgery. Three patients died. All were women. Subsequently, all patients who received definitive pelvic irradiation had small intestine roentgenograms to determine its location and mobility. Female patients, thin patients, and elderly patients had larger amounts of small intestine in the whole pelvis, a deeper cul de sac, and a greater incidence of relatively immobile small intestine. Patients with relatively immobile small intestine in the treatment field may be predisposed to injury. There was no relationship of the incidence of relatively immobile small intestine to prior pelvic surgery. We used the findings from the small intestine roentgenograms to modify individually the radiotherapy regimen so as to minimize the risk for small intestine injury. Patients were placed in the prone position to displace the small intestine out of the treatment fields used for booster dose irradiation. The treatment field was modified to exclude the small intestine. The total tumor dose delivered was determined by expectations for cure vs complications. To date, none of the patients in this study group has developed small intestine injury. Cadaver studies showed the feasibility of elective shortening of the pelvic cul de sac. The small intestine can be displaced away from the bladder, prostate, or cervix. (U.S.)

  17. Small Bowel Obstruction due to Intestinal Xanthomatosis

    Directory of Open Access Journals (Sweden)

    L. E. Barrera-Herrera

    2015-01-01

    Full Text Available Vast majority of bowel obstruction is due to postoperative adhesions, malignancy, intestinal inflammatory disease, and hernias; however, knowledge of other uncommon causes is critical to establish a prompt treatment and decrease mortality. Xanthomatosis is produced by accumulation of cholesterol-rich foamy macrophages. Intestinal xanthomatosis is an uncommon nonneoplastic lesion that may cause small bowel obstruction and several cases have been reported in the English literature as obstruction in the jejunum. We report a case of small intestinal xanthomatosis occurring in a 51-year-old female who presented with one day of copious vomiting and intermittent abdominal pain. Radiologic images revealed jejunal loop thickening and inflammatory changes suggestive of foreign body obstruction, diagnostic laparoscopy found two strictures at the jejunum, and a pathologic examination confirmed a segmental small bowel xanthomatosis. This case illustrates that obstruction even without predisposing factors such as hyperlipidemia or lymphoproliferative disorders.

  18. Radiodiagnosis of early radiation intestinal changes

    International Nuclear Information System (INIS)

    Volodina, G.I.; Abdulkhakova, D.A.

    1987-01-01

    X-ray examination of the colon in 102 patients and of the small intestine in 62 was performed during combined radiation therapy of cervical cancer and at different time after its discontinuation. Early radiation functional and morphological changes in the ileum and colon were detected. Radiation changes in the ileac mucosa were noted in 52% of the patients, changes of various degree in the rectal, sigmoid and cecal mucosa were noted in 41.2%. Moderate radiation changes in the ascending, descending and horizontal parts of the colon were noted in 10.7%. Early radiation intestinal injuries in the form of erosions and ulcers were revealed in 5.8% of the patients. In most of the patients radiation intestinal changes were without noticeable clinical manifestations. All these patients could be defined as a group at risk of developing late radiation changes

  19. Recent Advances in Intestinal Stem Cells.

    Science.gov (United States)

    McCabe, Laura R; Parameswaran, Narayanan

    2017-09-01

    The intestine is a dynamic organ with rapid stem cell division generating epithelial cells that mature and apoptose in 3-5 days. Rapid turnover maintains the epithelial barrier and homeostasis. Current insights on intestinal stem cells (ISCs) and their regulation are discussed here. The Lgr5+ ISCs maintain intestinal homeostasis by dividing asymmetrically, but also divide symmetrically to extinguish or replace ISCs. Following radiation or mucosal injury, reserve BMI1+ ISCs as well as other crypt cells can de-differentiate into Lgr5+ ISCs. ISC niche cells, including Paneth, immune and myofibroblast cells secrete factors that regulate ISC proliferation. Finally, several studies indicate that the microbiome metabolites regulate ISC growth. ISC cells can be plastic and integrate a complexity of environmental/niche cues to trigger or suppress proliferation as needed.

  20. Intestinal infarction: A complication of endovascular therapy

    Energy Technology Data Exchange (ETDEWEB)

    England, Andrew [Department of Radiology, South Manchester University Hospitals NHS Trust, Southmoor Road, Wythenshawe, Manchester M23 9LT (United Kingdom)]. E-mail: andrew.england@smtr.nhs.uk; Butterfield, John S. [Department of Radiology, South Manchester University Hospitals NHS Trust, Southmoor Road, Wythenshawe, Manchester M23 9LT (United Kingdom); Sukumar, Sathi [Department of Radiology, South Manchester University Hospitals NHS Trust, Southmoor Road, Wythenshawe, Manchester M23 9LT (United Kingdom); Thompson, David [Department of Radiology, South Manchester University Hospitals NHS Trust, Southmoor Road, Wythenshawe, Manchester M23 9LT (United Kingdom); Roulson, Jo-An [Department of Histopathology, South Manchester University Hospitals NHS Trust, Southmoor Road, Wythenshawe, Manchester M23 9LT (United Kingdom); Pritchard, Susan [Department of Histopathology, South Manchester University Hospitals NHS Trust, Southmoor Road, Wythenshawe, Manchester M23 9LT (United Kingdom); Ashleigh, Raymond J. [Department of Radiology, South Manchester University Hospitals NHS Trust, Southmoor Road, Wythenshawe, Manchester M23 9LT (United Kingdom)

    2007-08-15

    This report presents a rare case of intestinal infarction following endovascular therapy. A female patient who had undergone an internal carotid artery stenting procedure presented suddenly with abdominal pain. Radiological and clinical examinations at the time suggested a picture of intestinal ischaemia, in view of the patient's general conditions and co-existing morbidities surgical intervention was not considered to be an option. The patient died 4 days after the carotid stenting procedure, post-mortem examination revealed infarction of the ileum and caecum. The learning outcomes are if performing endovascular therapy in a patient with diffuse atherosclerotic disease early consideration of intestinal ischaemia should be given to any patient who presents with acute post-procedural abdominal pain.

  1. Intestinal infarction: A complication of endovascular therapy

    International Nuclear Information System (INIS)

    England, Andrew; Butterfield, John S.; Sukumar, Sathi; Thompson, David; Roulson, Jo-An; Pritchard, Susan; Ashleigh, Raymond J.

    2007-01-01

    This report presents a rare case of intestinal infarction following endovascular therapy. A female patient who had undergone an internal carotid artery stenting procedure presented suddenly with abdominal pain. Radiological and clinical examinations at the time suggested a picture of intestinal ischaemia, in view of the patient's general conditions and co-existing morbidities surgical intervention was not considered to be an option. The patient died 4 days after the carotid stenting procedure, post-mortem examination revealed infarction of the ileum and caecum. The learning outcomes are if performing endovascular therapy in a patient with diffuse atherosclerotic disease early consideration of intestinal ischaemia should be given to any patient who presents with acute post-procedural abdominal pain

  2. Seronegative Intestinal Villous Atrophy: A Diagnostic Challenge

    Directory of Open Access Journals (Sweden)

    Cláudio Martins

    2016-01-01

    Full Text Available Celiac disease is the most important cause of intestinal villous atrophy. Seronegative intestinal villous atrophy, including those that are nonresponsive to a gluten-free diet, is a diagnostic challenge. In these cases, before establishing the diagnosis of seronegative celiac disease, alternative etiologies of atrophic enteropathy should be considered. Recently, a new clinical entity responsible for seronegative villous atrophy was described—olmesartan-induced sprue-like enteropathy. Herein, we report two uncommon cases of atrophic enteropathy in patients with arterial hypertension under olmesartan, who presented with severe chronic diarrhea and significant involuntary weight loss. Further investigation revealed intestinal villous atrophy and intraepithelial lymphocytosis. Celiac disease and other causes of villous atrophy were ruled out. Drug-induced enteropathy was suspected and clinical improvement and histologic recovery were verified after olmesartan withdrawal. These cases highlight the importance for clinicians to maintain a high index of suspicion for olmesartan as a precipitant of sprue-like enteropathy.

  3. Viability of the vascularly perfused, recirculating rat intestine and intestine-liver preparations

    Energy Technology Data Exchange (ETDEWEB)

    Hirayama, H.; Xu, X.; Pang, K.S. (Univ. of Toronto, Ontario (Canada))

    1989-08-01

    Function and stability of vascularly perfused, recirculating in situ rat intestine (I) and intestine-liver (IL) preparations were evaluated in fasted and nonfasted rats because these techniques may be readily applied in drug metabolism studies. The rat intestine was perfused with blood medium (7.5 ml/min) via the superior mesenteric artery, with the venous outflow draining into the portal vein, which, together with hepatic arterial flow (2.5 ml/min), constituted the total blood flow (10 ml/min) to the liver. Maintenance of intestinal membrane integrity was observed. Rapid ({sup 14}C)glucose absorption against a concentration gradient and a lack of ({sup 3}H)-polyethylene glycol 4000 (PEG 4000, less than 4%) and Evans blue absorption by the recirculating I and IL preparations resulted after bolus injections of these markers into the pyloric end of the duodenum. Other indexes that revealed stable intestinal and liver functions were the following: preservation of reservoir perfusate volume, constancy in perfusion pressure, bile flow, and hemoglobin concentrations, evidence of intestinal glucose utilization and liver glucose production, and a lack of significant leakage of serum glutamic oxalic transaminase. The intestine and liver consumed oxygen at relatively constant rates, but the consumption rates for the fasted tissues (I or L) were significantly higher than those for nonfasted tissues. These results indicate that the vascularly perfused I and IL preparations were maintained in a viable and stable state for a 2-h perfusion period.

  4. Radiologic study on differential diagnosis of intestinal tuberculosis and intestinal Behcet's disease

    International Nuclear Information System (INIS)

    Kim, Jong Chul; Kim, Young Goo; Kim, Sang Joon; Choi, Byung Ihn; Park, Jae Hyung

    1986-01-01

    Radiologic findings in 30 patients with intestinal tuberculosis and 10 patients with intestinal Behcet's disease, who had been diagnosed at Seoul National University Hospital during the recent 5 years, were analysed retrospectively to evaluate the radiologic differential diagnosis of the two diseases. Intestinal tuberculosis severely involved the cecum, the ileocecal valve, the distal ileum and colons, but Behcet's disease mainly involved the distal ileum and infrequently the ileocecal valve and the cecum. The ulcers in tuberculosis were usually multiple small barium collected areas among pseudopolyps, on the contrary, those in Behcet's disease were multiple, discrete, well marinated, geographic, ring-like deep penetrating or collar-button shaped. Intestinal tuberculosis tended to involved long segments of intestines, with severer mucosal irregularity and deformity of the ileocecal valve and the ascending colon in comparison with Behcet's disease. Mesenteric and/or peritoneal involvement were accompanied in 1/3 cases of intestinal tuberculosis, and active pulmonary tuberculosis or pleural effusion also in 1/3 cases of intestinal tuberculosis.

  5. Intestinal Microbiota Signatures Associated With Histological Liver Steatosis in Pediatric-Onset Intestinal Failure.

    Science.gov (United States)

    Korpela, Katri; Mutanen, Annika; Salonen, Anne; Savilahti, Erkki; de Vos, Willem M; Pakarinen, Mikko P

    2017-02-01

    Intestinal failure (IF)-associated liver disease (IFALD) is the major cause of mortality in IF. The link between intestinal microbiota and IFALD is unclear. We compared intestinal microbiota of patients with IF (n = 23) with healthy controls (n = 58) using culture-independent phylogenetic microarray analysis. The microbiota was related to histological liver injury, fecal markers of intestinal inflammation, matrix metalloproteinase 9 and calprotectin, and disease characteristics. Overabundance of Lactobacilli, Proteobacteria, and Actinobacteria was observed in IF, whereas bacteria related to Clostridium clusters III, IV, and XIVa along with overall diversity and richness were reduced. Patients were segregated into 3 subgroups based on dominating bacteria: Clostridium cluster XIVa, Proteobacteria, and bacteria related to Lactobacillus plantarum. In addition to liver steatosis and fibrosis, Proteobacteria were associated with prolonged current parenteral nutrition (PN) as well as liver and intestinal inflammation. Lactobacilli were related to advanced steatosis and fibrosis mostly after weaning off PN without associated inflammation. In multivariate permutational analysis of variance, liver steatosis, bowel length, PN calories, and antibiotic treatment best explained the microbiota variation among patients with IF. Intestinal microbiota composition was associated with liver steatosis in IF and better predicted steatosis than duration of PN or length of the remaining intestine. Our results may be explained by a model in which steatosis is initiated during PN in response to proinflammatory lipopolysaccharides produced by Proteobacteria and progresses after weaning off PN, as the L plantarum group Lactobacilli becomes dominant and affects lipid metabolism by altering bile acid signaling.

  6. Neural regulation of intestinal nutrient absorption.

    Science.gov (United States)

    Mourad, Fadi H; Saadé, Nayef E

    2011-10-01

    The nervous system and the gastrointestinal (GI) tract share several common features including reciprocal interconnections and several neurotransmitters and peptides known as gut peptides, neuropeptides or hormones. The processes of digestion, secretion of digestive enzymes and then absorption are regulated by the neuro-endocrine system. Luminal glucose enhances its own absorption through a neuronal reflex that involves capsaicin sensitive primary afferent (CSPA) fibres. Absorbed glucose stimulates insulin release that activates hepatoenteric neural pathways leading to an increase in the expression of glucose transporters. Adrenergic innervation increases glucose absorption through α1 and β receptors and decreases absorption through activation of α2 receptors. The vagus nerve plays an important role in the regulation of diurnal variation in transporter expression and in anticipation to food intake. Vagal CSPAs exert tonic inhibitory effects on amino acid absorption. It also plays an important role in the mediation of the inhibitory effect of intestinal amino acids on their own absorption at the level of proximal or distal segment. However, chronic extrinsic denervation leads to a decrease in intestinal amino acid absorption. Conversely, adrenergic agonists as well as activation of CSPA fibres enhance peptides uptake through the peptide transporter PEPT1. Finally, intestinal innervation plays a minimal role in the absorption of fat digestion products. Intestinal absorption of nutrients is a basic vital mechanism that depends essentially on the function of intestinal mucosa. However, intrinsic and extrinsic neural mechanisms that rely on several redundant loops are involved in immediate and long-term control of the outcome of intestinal function. Copyright © 2011 Elsevier Ltd. All rights reserved.

  7. Bacteria, bile salts, and intestinal monosaccharide malabsorption

    Science.gov (United States)

    Gracey, Michael; Burke, Valerie; Oshin, Ademola; Barker, Judith; Glasgow, Eric F.

    1971-01-01

    Intestinal monosaccharide transport was studied in a series of rats with a self-filling jejunal blind loop using 3mM arbutin (p-hydroxyphenyl-B-glucoside) or 1mM D-fructose as substrate in vitro and 10 mM arbutin or 5mM D-fructose in vivo. These results were compared with changes in the bacterial flora and state of conjugation of intraluminal bile salts in those animals. Observations were also made of the microscopic and ultrastructural appearances of the small-intestinal epithelium. In the small intestine of blind-loop rats intestinal monosaccharide transport is impaired, and in vitro is most marked in the blind loop, less so in the efferent jejunum, and not significantly altered in the afferent jejunum. A similar pattern of disturbed monosaccharide absorption was demonstrated by perfusions in vivo. The degree of the transport defect correlates closely with the luxuriance of the anaerobic flora, which averaged 108 per millilitre in the blind loop, 107 in the efferent jejunum, and 106 in the afferent jejunum. A similar pattern of abnormality of bile salt conjugation occurred. In the blind loop the ratio of free to conjugated bile salts was grossly abnormal; this disturbance was somewhat less marked in the efferent jejunum and considerably less in the intraluminal contents of the afferent jejunum. An irregularly distributed lesion, consisting of swelling and vacuolation of microvilli and intracellular organelles, was demonstrated in the small-intestinal epithelium of blind-loop animals. Impaired absorption of monosaccharides is a further consequence of bacterial contamination of the upper gut. It is suggested that this defect is caused by the presence of high levels of deconjugated bile salts produced by an abnormal anaerobic bacterial flora in the small intestine. ImagesFig. 3Fig. 4 PMID:4329096

  8. CRITERIOS PARA LA ELABORACIÓN DE MAPAS DE PROCESOS. PARTICULARIDADES PARA LOS SERVICIOS HOSPITALARIOS

    Directory of Open Access Journals (Sweden)

    Dianelys Nogueira Rivera

    2009-05-01

    Full Text Available

    Para responder a las necesidades de un entorno cambiante, se hace necesario  modificar el funcionamiento de las organizaciones, o sea, sus procesos. Ya no se piensa en diseños con una estructura inmutable con el paso de los años, sino permanentemente sometidos a revisiones, en virtud de que cada proceso de por sí es mejorable. Actualmente, las instituciones de salud luchan por incorporar herramientas y modelos de gestión como: Benchmarking, Gestión por Procesos o Reingeniería e intentan generalizar la revisión de los procesos como una práctica sistemática, que a la vez forme parte de la cultura médica. Como base para la mejora, es extendido el uso de los mapas de procesos que, a partir de varios enfoques, permiten la visualización y apreciación de las interrelaciones entre los procesos, y actividades para perfeccionar los resultados que los clientes desean. Este trabajo propone un procedimiento para la elaboración de mapas de procesos de servicios hospitalarios, a partir del análisis bibliográfico y la evaluación en la práctica social.

  9. The effect of fucoidan on intestinal flora and intestinal barrier function in rats with breast cancer.

    Science.gov (United States)

    Xue, Meilan; Ji, Xinqiang; Liang, Hui; Liu, Ying; Wang, Bing; Sun, Lingling; Li, Weiwei

    2018-02-21

    Recent research studies have shown that the intestinal flora are related to the occurrence and progress of breast cancer. This study investigates the effect of fucoidan on intestinal flora and intestinal barrier function in rats with 7,12-dimethylbenz[a]anthracene (DMBA)-induced breast cancers. Sixty female Sprague-Dawley rats were randomly assigned to the control group, the model group, and the F1 and F2 groups, which were fed fucoidan at concentrations of 200 and 400 mg per kg bw (body weight), respectively. Intestinal histopathological analysis was performed and 16S rDNA high-throughput sequencing was used to provide an overview of the intestinal flora composition. The contents of d-lactic acid (d-LA), diamine oxidase (DAO) and endotoxin in plasma were detected by ELISA. Expression levels of the tight junction (TJ) proteins, phosphorylated p38 MAPK and ERK1/2 were measured using western blotting. Our results suggested that the intestinal wall of the model group was damaged. However, after fucoidan intervention, the villi were gradually restored. ELISA showed that the levels of plasma endotoxin, d-LA and DAO decreased in the F1 and F2 groups compared to those in the model group. Fucoidan treatment also increased the expressions of ZO-1, occludin, claudin-1 and claudin-8. Furthermore, the expression levels of phosphorylated p38 MAPK and ERK1/2 were upregulated in fucoidan treatment groups. The results of 16S rDNA high-throughput sequencing indicated that fucoidan increased the diversity of the intestinal microbiota and induced changes in microbial composition, with the increased Bacteroidetes/Firmicutes phylum ratio. In conclusion, the supplement of fucoidan could improve the fecal microbiota composition and repair the intestinal barrier function. The study suggested the use of fucoidan as an intestinal flora modulator for potential prevention of breast cancer.

  10. Persistently increased intestinal fraction of alkaline phosphatase

    DEFF Research Database (Denmark)

    Nathan, E; Baatrup, G; Berg, H

    1984-01-01

    Persistent elevation of the intestinal fraction of the alkaline phosphatase (API) as an isolated finding has to our knowledge not been reported previously. It was found in a boy followed during a period of 5.5 years. The only symptom was transient periodic fatigue observed at home, but not apparent...... during hospitalization. His blood type was O, RH+, Le (a-, b+) and he was a secretor of H-substance, which may be associated with rising API activity after fat-loading. In this case API was unchanged after fat-loading. Neither intestinal nor liver diseases were found, and no other cause for the elevated...

  11. Relationships between intestinal parasitosis and handedness.

    Science.gov (United States)

    Uslu, Hakan; Dane, Senol; Uyanik, M Hamidullah; Ayyildiz, Ahmet

    2010-07-01

    The aim of the study was to investigate if there is a possible relation between intestinal parasitosis and handedness in patients with suspected intestinal parasitosis. Hand preference was assessed on the Edinburgh Handedness Inventory. Stool samples were examined microscopically for the presence of parasite. In the present study right-handers had many more helminth infections and left-handers had many more protozoon infections. Lower rate of helminth infections in the present study, and higher asthma incidences in the left-handed population in literature, may be associated with different immune machinery in left-handed people than in right-handed ones.

  12. Translational control of an intestinal microvillar enzyme

    DEFF Research Database (Denmark)

    Danielsen, E M; Cowell, G M; Sjöström, H

    1986-01-01

    The rates of biosynthesis of adult and foetal pig small-intestinal aminopeptidase N (EC 3.4.11.2) were compared to determine at which level the expression of the microvillar enzyme is developmentally controlled. In organ-cultured explants, the rate of biosynthesis of foetal aminopeptidase N is only...... about 3% of the adult rate. The small amount synthesized occurs in a high-mannose-glycosylated, membrane-bound, form that is processed to the mature, complex-glycosylated, form at a markedly slower rate than that of the adult enzyme. Extracts of total RNA from adult and foetal intestine contained...

  13. Verification of chronic intestinal ischemia by angiography

    Energy Technology Data Exchange (ETDEWEB)

    Stolze, T.; Sandmann, W.

    1982-06-25

    With chronical occlusion of an intestianal artery (coeliac artery, superior and inferior mesenteric artery) functionally acting and organ-supplying collateral circulations may develop. When this collateral circulation provides a sufficient blood supply, uncharacteristic (10) and absent or minor clinical symptomatology (21) result and therefore in many cases such vascular occlusions are not detected in older people. Consequently, the possible existence of an intestinal ischaemia should be taken into consideration when indefinite complaints occur in older patients, particularly in those cases, where arterial occlusions exist in the lower extremities. With chronical intestinal (arteriosclerotic) ischaemia an acute thrombo-embolism has always to be regarded as a possible complication.

  14. Transcriptome changes during intestinal cell differentiation

    DEFF Research Database (Denmark)

    Tadjali, Mehrdad; Seidelin, Jakob B; Olsen, Jørgen

    2002-01-01

    The expression of 18149 genes have been analysed during the differentiation of the human intestinal cell line Caco-2. cDNA probes from undifferentiated and differentiated Caco-2 cells were separately hybridised to EST DNAs spotted in an array on a nylon membrane. A remarkable change in the transc......The expression of 18149 genes have been analysed during the differentiation of the human intestinal cell line Caco-2. cDNA probes from undifferentiated and differentiated Caco-2 cells were separately hybridised to EST DNAs spotted in an array on a nylon membrane. A remarkable change...

  15. Intestinal tuberculosis sometimes mimics Crohn's disease.

    Directory of Open Access Journals (Sweden)

    Esfandiar Shojaei

    2013-11-01

    Full Text Available Intestinal tuberculosis is an uncommon presentation of tuberculosis (TB and has clinicopathological similarities with Crohn's disease. In regions where TB is endemic clinicians must aware of this condition and fully evaluate their patients when Crohn's disease is diagnosed. We recommend all pathologic specimens be evaluate effectively for TB.Smear,culture and PCR for Mycobacterium.tuberculosis from samples aside the pathological reviews help for better diagnosis. Here we present a case of intestinal tuberculosis which initially diagnosed as Crohn's disease but after starting immunosuppressive agents he presented with disseminated tuberculosis.

  16. A new approach to predict human intestinal absorption using porcine intestinal tissue and biorelevant matrices.

    Science.gov (United States)

    Westerhout, Joost; van de Steeg, Evita; Grossouw, Dimitri; Zeijdner, Evelijn E; Krul, Cyrille A M; Verwei, Miriam; Wortelboer, Heleen M

    2014-10-15

    A reliable prediction of the oral bioavailability in humans is crucial and of high interest for pharmaceutical and food industry. The predictive value of currently used in silico methods, in vitro cell lines, ex vivo intestinal tissue and/or in vivo animal studies for human intestinal absorption, however, is often insufficient, especially when food-drug interactions are evaluated. Ideally, for this purpose healthy human intestinal tissue is used, but due to its limited availability there is a need for alternatives. The aim of this study was to evaluate the applicability of healthy porcine intestinal tissue mounted in a newly developed InTESTine™ system to predict human intestinal absorption of compounds with different chemical characteristics, and within biorelevant matrices. To that end, first, a representative set of compounds was chosen of which the apparent permeability (Papp) data in both Caco-2 cells and human intestinal tissue mounted in the Ussing chamber system, and absolute human oral bioavailability were reported. Thereafter, Papp values of the subset were determined in both porcine jejunal tissue and our own Caco-2 cells. In addition, the feasibility of this new approach to study regional differences (duodenum, jejunum, and ileum) in permeability of compounds and to study the effects of luminal factors on permeability was also investigated. For the latter, a comparison was made between the compatibility of porcine intestinal tissue, Caco-2 cells, and Caco-2 cells co-cultured with the mucin producing HT29-MTX cells with biorelevant samples as collected from an in vitro dynamic gastrointestinal model (TIM). The results demonstrated that for the paracellularly transported compounds atenolol, cimetidine, mannitol and ranitidine porcine Papp values are within 3-fold difference of human Papp values, whereas the Caco-2 Papp values are beyond 3-fold difference. Overall, the porcine intestinal tissue Papp values are more comparable to human Papp values (9 out

  17. Sodium recirculation and isotonic transport in toad small intestine

    DEFF Research Database (Denmark)

    Nedergaard, Signe Nielsen; Larsen, Erik Hviid; Ussing, Hans H.

    1999-01-01

    Small intestine; leaky epithelia; solute-coupled water transport; Na*O+ recirculation; lateral intercellular space; flux ratio analysi......Small intestine; leaky epithelia; solute-coupled water transport; Na*O+ recirculation; lateral intercellular space; flux ratio analysi...

  18. Diversity of human small intestinal Streptococcus and Veillonella populations

    NARCIS (Netherlands)

    Bogert, B. van den; Erkus, O.; Boekhorst, J.; Goffau, M. de; Smid, E.J.; Zoetendal, E.G.; Kleerebezem, M

    2013-01-01

    Molecular and cultivation approaches were employed to study the phylogenetic richness and temporal dynamics of Streptococcus and Veillonella populations in the small intestine. Microbial profiling of human small intestinal samples collected from four ileostomy subjects at four time points displayed

  19. Surgical management and autologous intestinal reconstruction in short bowel syndrome

    NARCIS (Netherlands)

    Hommel, Matthijs J.; van Baren, Robertine; Haveman, Jan Willem

    Short bowel syndrome (SBS) is a serious condition with considerable morbidity and mortality. When treatment with parenteral nutrition fails and life-threatening complications occur, autologous intestinal reconstruction (AIR) should be considered before intestinal transplantation (ITx). Single or

  20. Plasmodium berghei ANKA causes intestinal malaria associated with dysbiosis.

    Science.gov (United States)

    Taniguchi, Tomoyo; Miyauchi, Eiji; Nakamura, Shota; Hirai, Makoto; Suzue, Kazutomo; Imai, Takashi; Nomura, Takahiro; Handa, Tadashi; Okada, Hiroko; Shimokawa, Chikako; Onishi, Risa; Olia, Alex; Hirata, Jun; Tomita, Haruyoshi; Ohno, Hiroshi; Horii, Toshihiro; Hisaeda, Hajime

    2015-10-27

    Gastrointestinal symptoms, such as abdominal pain and diarrhea, are frequently observed in patients with Plasmodium falciparum malaria. However, the correlation between malaria intestinal pathology and intestinal microbiota has not been investigated. In the present study, infection of C57BL/6 mice with P. berghei ANKA (PbA) caused intestinal pathological changes, such as detachment of epithelia in the small intestines and increased intestinal permeability, which correlated with development with experimental cerebral malaria (ECM). Notably, an apparent dysbiosis occurred, characterized by a reduction of Firmicutes and an increase in Proteobacteria. Furthermore, some genera of microbiota correlated with parasite growth and/or ECM development. By contrast, BALB/c mice are resistant to ECM and exhibit milder intestinal pathology and dysbiosis. These results indicate that the severity of cerebral and intestinal pathology coincides with the degree of alteration in microbiota. This is the first report demonstrating that malaria affects intestinal microbiota and causes dysbiosis.

  1. Surgical aspects of intestinal tuberculosis in children: Our experience

    African Journals Online (AJOL)

    constrained countries. Intestinal TB is especially notorious as a number of cases have to be dealt surgically, which too have morbidity and mortality. This study was conducted to identify various presentations of intestinal TB necessitating surgical ...

  2. Diversity of human small intestinal Streptococcus and Veillonella populations

    NARCIS (Netherlands)

    van den Bogert, Bartholomeus; Erkus, Oylum; Boekhorst, Jos; de Goffau, Marcus; Smid, Eddy J.; Zoetendal, Erwin G.; Kleerebezem, Michiel

    Molecular and cultivation approaches were employed to study the phylogenetic richness and temporal dynamics of Streptococcus and Veillonella populations in the small intestine. Microbial profiling of human small intestinal samples collected from four ileostomy subjects at four time points displayed

  3. Dimethyloxalylglycine preserves the intestinal microvasculature and protects against intestinal injury in a neonatal mouse NEC model: role of VEGF signaling.

    Science.gov (United States)

    Bowker, Rakhee M; Yan, Xiaocai; Managlia, Elizabeth; Liu, Shirley X L; Marek, Catherine; Tan, Xiao-Di; De Plaen, Isabelle G

    2018-02-01

    BackgroundNecrotizing enterocolitis (NEC) is a devastating neonatal disease characterized by intestinal necrosis. Hypoxia-inducible factor-1α (HIF-1α) has a critical role in cellular oxygen homeostasis. Here, we hypothesized that prolyl hydroxylase (PHD) inhibition, which stabilizes HIF-1α, protects against NEC by promoting intestinal endothelial cell proliferation and improving intestinal microvascular integrity via vascular endothelial growth factor (VEGF) signaling.MethodsTo assess the role of PHD inhibition in a neonatal mouse NEC model, we administered dimethyloxalylglycine (DMOG) or vehicle to pups before or during the NEC protocol, and determined mortality and incidence of severe intestinal injury. We assessed intestinal VEGF by western blot analysis and quantified endothelial cell and epithelial cell proliferation following immunofluorescence.ResultsDMOG decreased mortality and incidence of severe NEC, increased intestinal VEGF expression, and increased intestinal villus endothelial and epithelial cell proliferation in experimental NEC. Inhibiting VEGFR2 signaling eliminated DMOG's protective effect on intestinal injury severity, survival, and endothelial cell proliferation while sparing DMOG's protective effect on intestinal epithelial cell proliferation.ConclusionDMOG upregulates intestinal VEGF, promotes endothelial cell proliferation, and protects against intestinal injury and mortality in experimental NEC in a VEGFR2 dependent manner. DMOG's protective effect on the neonatal intestinal mucosa may be mediated via VEGFR2 dependent improvement of the intestinal microvasculature.

  4. Commensal Bacteria and Epithelial Cross Talk in the Developing Intestine

    OpenAIRE

    Rautava, Samuli; Walker, W. Allan

    2007-01-01

    Indigenous intestinal microbes have co-evolved with the intestinal immune system to form a symbiotic ecosystem. In the postnatal period, intestinal microbes provide the developing gut with stimuli that are necessary for healthy maturation of the intestinal immune system. Cross talk between the host and commensal microbes is an essential component of gut homeostasis mechanisms also in later life. During recent years, innovative research has shed light on the molecular mechanisms of these inter...

  5. Intestinal sclerosis with pseudo-obstruction in three dogs.

    Science.gov (United States)

    Moore, R; Carpenter, J

    1984-04-01

    Intestinal sclerosis causing chronic intestinal pseudo-obstruction was diagnosed in 3 dogs. The pseudo-obstruction was characterized by vomiting and weight loss of 2 weeks' to 3 months' duration. A patent intestinal lumen was determined by contrast radiography and verified at surgery. Intestinal biopsy revealed diffuse atrophy, fibrosis, and mononuclear cell infiltration of the tunica muscularis. Each dog was euthanatized because of a progressive, deteriorating clinical course.

  6. LA GESTIÓN POR PROCESOS: UN ENFOQUE DE GESTIÓN EFICIENTE

    Directory of Open Access Journals (Sweden)

    Miguel Ángel Mallar

    2010-01-01

    Full Text Available Cada vez más se observan los esfuerzos orientados a adecuar las organizaciones al complejo escenario en que se mueven. Cambios de reglas de juego, incremento de la competencia, apertura al mundo a través de la tecnología, hacen al cliente mucho más exigente, modificando sus demandas y necesidades.La Gestión basada en los Procesos, surge como un enfoque que centra la atención sobre las actividades de la organización, para optimizarlas.En este trabajo se considerará a la organización como una red de procesos interrelacionados o interconectados, donde la estructura organizativa vertical clásica, eficiente a nivel de funciones, se orienta hacia una concepción horizontal, desplazándose el centro de interés desde las estructuras hacia los procesos, como metodología para mejorar el rendimiento, concentrándose en el diseño disciplinado y cuidadosa ejecución de todos los procesos de una organización.Concluyendo, la metodología de aplicación de la Gestión basada en Procesos se trata de una herramienta de gestión adecuada para el momento actual, constituyéndose con fuerza como una alternativa exitosa para la obtención de resultados cada vez mejores.

  7. Beneficios de la aplicación de normas internacionales ISO en procesos electorales

    Directory of Open Access Journals (Sweden)

    Jeffrey Badí Quinteros Basantes

    2017-01-01

    Full Text Available En este artículo se presentarán los beneficios de la aplicabilidad de las normas internacionales ISO en los procesos electorales, con el fin de poder elevar los niveles de percepción positiva de los ciudadanos. Se verificará la aplicación de normas ISO/TS 17582:2014, Sistemas de Gestión de la Calidad y la norma ISO/IEC 27001:2013, para todas las fases de un proceso electoral. Se expondrán los dominios que forman parte de la norma ISO/TS 17582:2014 , los cuales permiten un proceso de mejoramiento continuo a fin de garantizar la calidad de las metodologías que soportan la organización, administración, gestión, seguimiento y auditorías de un proceso electoral. La norma ISO/IEC 27001:2013 se alinea con la norma ISO9001:2008 para la gestión de seguridad de la información. La aplicación de esta normativa permitirá asegurar la integridad, confidencialidad y disponibilidad de la información durante los procesos electorales.

  8. Desarrollo de un marco de trabajo para facilitar el análisis para la mejora y optimización de procesos de negocio soportado por técnicas y herramientas de Minería de Procesos

    OpenAIRE

    Diosa Giraldo, Jonathan Alexander

    2014-01-01

    Para realizar la entrega de un producto o servicio las organizaciones llevan a cabo procesos de negocio operacionales donde se realizan interacciones entre diferentes personas, recursos y sistemas de información -- La minería de procesos hace un aprovechamiento de los logs o traza que dejan los sistemas de información que soportan dichos procesos operacionales y al aplicar diferentes algoritmos de minería permiten hacer un descubrimiento automático del modelo de proceso en ejecución -- Sin em...

  9. El debido proceso como derecho fundamental de los estudiantes universitarios en los procesos sancionatorios adelantados por las universidades: un análisis a partir de la jurisprudencia de la corte constitucional colombiana

    OpenAIRE

    Ana Patricia Pabón Mantilla; Silvia Juliana Pradilla Rivera; Cesar Javier Valencia Caballero

    2008-01-01

    Se presenta un análisis realizado con base en los pronunciamientos emanados de la Corte Constitucional en lo que se refiere a los procesos disciplinarios adelantados por las universidades a estudiantes. Se contemplan aspectos como la autonomía universitaria, el debido proceso, el derecho a la educación. Se busca identificar los elementos mínimos que deben contener los procesos disciplinarios para que se ajusten al respeto del derecho al debido proceso y al derecho a...

  10. El debido proceso como derecho fundamental de los estudiantes universitarios en los procesos sancionatorios adelantados por las universidades: un análisis a partir de la jurisprudencia de la corte constitucional colombiana

    Directory of Open Access Journals (Sweden)

    Ana Patricia Pabón Mantilla

    2008-01-01

    Full Text Available Se presenta un análisis realizado con base en los pronunciamientos emanados de la Corte Constitucional en lo que se refiere a los procesos disciplinarios adelantados por las universidades a estudiantes. Se contemplan aspectos como la autonomía universitaria, el debido proceso, el derecho a la educación. Se busca identificar los elementos mínimos que deben contener los procesos disciplinarios para que se ajusten al respeto del derecho al debido proceso y al derecho a la igualdad.

  11. Microdialysis in the assessment of regional intestinal ischemia

    DEFF Research Database (Denmark)

    Sommer, Thorbjørn

     The Ph.D.thesis “Microdialysis in the assessment of regional intestinal ischemia” is based on three scientific papers. The diagnosis of intestinal ischemia remains a diagnostic challenge, since no technique has been able to monitor the intestinal perfusion continuously with a high sensitivity an...

  12. Intestinal failure in childhood | Goulet | South African Journal of ...

    African Journals Online (AJOL)

    Intestinal failure (IF) requires the use of parenteral nutrition (PN) for as long as it persists and in case of irreversible IF may be an indication for intestinal transplantation (ITx). Biological evaluation of IF is becoming possible with the use of plasma citrulline as a marker of intestinal mass. Short bowel syndrome (SBS) is the ...

  13. Effects of Radiation on the Microbiota and Intestinal Inflammatory Disease

    Science.gov (United States)

    2016-09-01

    evaluating the effects of these changes on intestinal susceptibility to inflammatory disease. 15. SUBJECT TERMS Radiation, microbiome , mycobiome...immune cells associated with the intestine and their interactions with the normal microbial contents of the gut. 2. KEYWORDS Radiation, microbiome ... microbiome following TBI. At the end of the experiment, we also harvested the intestines and mesenteric lymph nodes for multiparametric flow cytometry and

  14. Community and genomic analysis of the human small intestine microbiota

    NARCIS (Netherlands)

    Bogert, van den B.

    2013-01-01

    Our intestinal tract is densely populated by different microbes, collectively called microbiota, of which the majority are bacteria. Research focusing on the intestinal microbiota often use fecal samples as a representative of the bacteria that inhabit the end of the large intestine.

  15. The small intestine microbiota, nutritional modulation and relevance for health

    NARCIS (Netherlands)

    El Aidy, Sahar; van den Bogert, Bartholomeus; Kleerebezem, Michiel

    The intestinal microbiota plays a profound role in human health and extensive research has been dedicated to identify microbiota aberrations that are associated with disease. Most of this work has been targeting the large intestine and fecal microbiota, while the small intestine microbiota may also

  16. Asymptomatic Intestinal Parasites in School Children at Ota, Ogun ...

    African Journals Online (AJOL)

    Asymptomatic Intestinal Parasites in School Children at Ota, Ogun State. ... This study thus advocates routine periodic screening even of the healthy pupils for intestinal parasitosis to minimize morbidity and mortality and improve ... Key Words: intestinal parasites, Giardia lamblia, Entamoeba histolytica, School, Nigeria ...

  17. Prevalence of intestinal parasites and bacteria among food handlers ...

    African Journals Online (AJOL)

    No intestinal parasites were detected from fingernail contents. Forty six (23%) stool specimens were positive for intestinal para¬sites. Giardia lamblia 18 (9%) was most frequent among the 10 different types of detected intestinal parasites followed by Entamoeba histolytica 9 (4.5%). No pathogenic bacteria were detected in ...

  18. Observations on the origin of congenital intestinal atresia

    African Journals Online (AJOL)

    The article by Louw and Barnard entitled 'Congenital intestinal atresia – observations on its origin' published in The Lancet in. 19951 was a landmark paper that elucidated the pathogenesis of intestinal atresia and radically altered the surgical treatment of the condition. As a result of a review of cases of intestinal atresia at.

  19. Pattern Of Intestinal Obstruction In A Semiurban Nigerian Hospital ...

    African Journals Online (AJOL)

    Adhesive intestinal obstruction is the commonest cause in this semi-urban population which was studied. Obstructed hernia is becoming increasingly less common as a cause of intestinal obstruction. Keywords: Pattern, Intestinal Obstruction, Semiurban Hospital. Nigerian Journal of Clinical Practice Vol. 11 (4) 2008: pp.

  20. Intestinal schistosomiasis associated with intussusception: a case ...

    African Journals Online (AJOL)

    Abstract: We report a case of intestinal schistosomiasis associated with iliocaecal intussusception resulting from obstructions of the terminal part of the ileum by schistosome egg-induced fibrosis. A 7- year-old boy presented with the history of abdominal pain and difficulties in passing stool for two months. Ultrasound ...

  1. Intestinal perforation caused by multiple magnet ingestion

    Directory of Open Access Journals (Sweden)

    Nergul Corduk

    2014-01-01

    Full Text Available Multiple magnet ingestion is rare, but can cause serious gastrointestinal complications. We report a case of 7-year-old girl with multiple intestinal perforations caused by multiple magnet ingestion. The aim of this report is to draw attention to magnetic toys, results of magnet ingestion and the importance of timing of operation.

  2. Performance, Nutrient Utilization and Intestinal Environment of ...

    African Journals Online (AJOL)

    The performance, nutrient utilization and intestinal environment of weaned rabbits fed diets supplemented with organic acids (acetic acid, citric acid and formic acid) were investigated with 24 (6-week old) rabbits in a completely randomized design. The control diet was not supplemented while others were supplemented ...

  3. Colonoscopic features of early intestinal tuberculosis

    African Journals Online (AJOL)

    1991-03-02

    Mar 2, 1991 ... resembled sessile polyps. They occurred ... the colonoscopic diagnosis of intestinal tuberculosis has, until recently ... Transverse colon. Ascending colon. Rectum. Caecum. Transverse colon. Caecum and ascending colon. Caecum and transverse colon*. Caecum, ascending and transverse colon*. Caecum ...

  4. Repairing organs : lessons from intestine and liver

    NARCIS (Netherlands)

    Gehart, Helmuth; Clevers, Hans

    The concept of organ regeneration has fascinated humanity from ancient mythology to modern science fiction. Recent advances offer the potential to soon bring such technology within the grasp of clinical medicine. Rapidly expanding insights into the intrinsic repair processes of the intestine and

  5. Repairing organs : lessons from intestine and liver

    NARCIS (Netherlands)

    Gehart, Helmuth; Clevers, Hans

    2015-01-01

    The concept of organ regeneration has fascinated humanity from ancient mythology to modern science fiction. Recent advances offer the potential to soon bring such technology within the grasp of clinical medicine. Rapidly expanding insights into the intrinsic repair processes of the intestine and

  6. Rage mediated DAMP signaling in intestinal tumorigenesis

    NARCIS (Netherlands)

    Heijmans, Jarom; Büller, Nikè V. J. A.; Muncan, Vanesa; van den Brink, Gijs R.

    2012-01-01

    In the intestine, a large variety of pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) can instigate innate immune responses, which have been shown to promote colorectal carcinogenesis. We have recently demonstrated an important role for the receptor for

  7. Congenital Central Hypoventilation Syndrome And Intestinal

    African Journals Online (AJOL)

    to progressive hypercapnia and sustained hypoxaemia. Neonates with this condition experience hypoventilation or apnoea while asleep. Patients may also have congenital intestinal aganglionosis (CIA), aganglionic megacolon or Hirschsprung's disease, suggesting an aberrant phenotype arising from a defect of migration ...

  8. characterization of intestinal microbiota in celiac children

    African Journals Online (AJOL)

    F. Lahcene1*, A. Tir Touil Meddah1, K. Bouziane-Nedjadi2, B. Meddah1, A. Leke3

    2016-09-01

    Sep 1, 2016 ... In this study, 13 Samples of intestinal biopsy, ... Research Article. Journal of Fundamental and Applied Sciences is licensed under a Creative Commons Attribution-NonCommercial 4.0. International License. ... disease are caused by several factors among, the ingestion of gluten, and it has been suggested.

  9. Postoperative Adhesive Intestinal Obstruction from Gossypiboma ...

    African Journals Online (AJOL)

    We report a case of 41.year.old female admitted with features of intestinal obstruction and had a previous history of hysterectomy performed 2 months back at another hospital. Pathologists must be aware of this entity and its proper reporting as the cases are liable to go to court. Surgeons must recognize the risk factors that ...

  10. Intestinal amino acid metabolism in neonates

    NARCIS (Netherlands)

    van Goudoever, Johannes B.; van der Schoor, Sophie R. D.; Stoll, Barbara; Burrin, Douglas G.; Wattimena, Darcos; Schierbeek, Henk; Schaart, Maaike W.; Riedijk, Maaike A.; van der Lugt, Jasper

    2006-01-01

    The portal-drained viscera (stomach, intestine, pancreas and spleen) have a much higher rate of both energy expenditure and protein synthesis than can be estimated on the basis of their weight. A high utilization rate of dietary nutrients by the portal-drained viscera might result in a low systemic

  11. Unusual cause of neonatal intestinal obstruction | Zikavska ...

    African Journals Online (AJOL)

    There are many causes of intestinal obstruction in the neonatal age. The most common types are mechanical and result from congenital malformations of the gastrointestinal tract. However, functional disorders also occur. In some cases, diagnosis can be made prenatally but in others manifestation occurs after birth. The aim ...

  12. Pig models on intestinal development and therapeutics.

    Science.gov (United States)

    Yin, Lanmei; Yang, Huansheng; Li, Jianzhong; Li, Yali; Ding, Xueqing; Wu, Guoyao; Yin, Yulong

    2017-12-01

    The gastrointestinal tract plays a vital role in nutrient supply, digestion, and absorption, and has a crucial impact on the entire organism. Much attention is being paid to utilize animal models to study the pathogenesis of gastrointestinal diseases in response to intestinal development and health. The piglet has a body size similar to that of the human and is an omnivorous animal with comparable anatomy, nutritional requirements, and digestive and associated inflammatory processes, and displays similarities to the human intestinal microbial ecosystem, which make piglets more appropriate as an animal model for human than other non-primate animals. Therefore, the objective of this review is to summarize key attributes of the piglet model with which to study human intestinal development and intestinal health through probing into the etiology of several gastrointestinal diseases, thus providing a theoretical and hopefully practical, basis for further studies on mammalian nutrition, health, and disease, and therapeutics. Given the comparable nutritional requirements and strikingly similar brain developmental patterns between young piglets and humans, the piglet has been used as an important translational model for studying neurodevelopmental outcomes influenced by pediatric nutrition. Because of similarities in anatomy and physiology between pigs and mankind, more emphasises are put on how to use the piglet model for human organ transplantation research.

  13. Peritoneal drainage for newborn intestinal perforation: primary ...

    African Journals Online (AJOL)

    Keywords: intestinal perforation in newborn, necrotizing enterocolitis, primary peritoneal drainage. Department of Surgery, Paul L. Foster School of Medicine, Texas Tech University. HSC, El Paso, Texas, USA. Correspondence to Donald E. Meier, MD, Department of Surgery, Paul L. Foster. School of Medicine, Texas Tech ...

  14. Genetics Home Reference: intestinal pseudo-obstruction

    Science.gov (United States)

    ... branching network of filaments that make up the cytoskeleton , which gives structure to cells and allows them to change shape and move. ... 2 actin protein is found in smooth muscle cells of the intestinal and urinary ... filaments in the cytoskeleton and reduce the ability of smooth muscles in ...

  15. Intestinal Parasites of the Grasscutter (Thryonomys swinderianus ...

    African Journals Online (AJOL)

    The intestinal content of the animals were examined with the aid of a hand lens, a microscope and direct smear method. The parasites identified include helminthes such as Ancylostoma sp., Trichuris sp., Ascaris sp., Hymenolepis sp. and Schistosoma haematobium, and protozoans such as Giardia sp. and Entamoeba sp.

  16. What's new in Osmosin and intestinal perforation?

    Science.gov (United States)

    Laidler, P; Maslin, S C; Gilhome, R W

    1985-07-01

    New formulations of drugs may have unexpected side effects. Osmosin is a new osmotic-pump controlled-release formulation of Indomethacin, designed to prevent gastrointestinal irritation. However, in a small number of cases the use of Osmosin has coincided with perforation of the small and large intestine, probably because passage of the tablet through the gastrointestinal tract was impeded.

  17. Prevalence of opportunistic intestinal parasites and associated ...

    African Journals Online (AJOL)

    Therefore, frequent assessment of the magnitude and associated factors for intestinal parasitosis is essential for the management of HIV/AIDS patients. Methods: A hospital based cross-sectional study was conducted among patients attending Arba Minch Hospital Antiretroviral Therapy (ART) Clinic from March to June 2016.

  18. Intestinal obstruction secondary to infantile polyarteritis nodosa ...

    African Journals Online (AJOL)

    Polyarteritis Nodosa (PAN) is a rare systemic necrotising vasculitis of medium and small-sized arteries. Patients typically present with systemic symptoms. Obstructive intestinal symptoms are described but usually resolve with treatment of the underlying vascular disease. We report a case of a one year old boy with multiple ...

  19. Assessment of intestinal peristalsis in vitro.

    Science.gov (United States)

    Pozzoli, Cristina; Poli, Enzo

    2012-11-01

    The protocol detailed in this unit is designed to assess intestinal peristaltic motility in the isolated small intestine in vitro and to measure the effects of drugs able to interfere with gut propulsive activity. The procedure is based on Trendelenburg's classic technique, described at the beginning of the 20th century in the isolated guinea pig ileum and, later on, extended to other intestinal preparations from the same animal and other animal species. This unit illustrates the basic procedures for setting up the intestinal preparation, recording peristalsis under near-physiologic conditions, and testing the pharmaco-toxicological effects of drugs and pollutants on the contractile behavior of the gut wall. The protocol allows evaluating the action of drugs affecting sensory and/or motor neurons of the enteric nervous system and how these neurons control the development of the motor program of the gut wall. This model can be exploited to investigate novel compounds undergoing preclinical development and both inhibitors and stimulants of gastrointestinal peristaltic activity, as well as environmental or alimentary pollutants, like xenobiotics and naturally-occurring toxins, endowed with noxious activity with regard to digestive functions.

  20. Schistosomiasis and intestinal helminth infections in Sengerema

    African Journals Online (AJOL)

    Abstract: Schistosomiasis and intestinal helminth infections are common health problems among the people of Lake. Victoria basin particularly in Mwanza ... these infections is largely lacking and that biomedical studies give only a partial ... sampling procedure was such that in each sub-village. ' Correspondence: Joseph R.

  1. Periarrest intestinal bacterial translocation and resuscitation outcome.

    Science.gov (United States)

    Chalkias, Athanasios; Scheetz, Marc H; Gulati, Anil; Xanthos, Theodoros

    2016-02-01

    During the periarrest period, intestinal ischemia may result in barrier dysfunction and bacterial translocation, which has clear mechanistic links to inflammation and cascade stimulation, especially in patients who are treated with therapeutic hypothermia. Despite optimal management, periarrest bacterial translocation may worsen the outcome of cardiac arrest victims. Copyright © 2015 Elsevier Inc. All rights reserved.

  2. Intestinal helminth infections among pregnant Cameroonian women ...

    African Journals Online (AJOL)

    Objectives: To investigate the prevalence and intensity of intestinal helminth infections in pregnant Cameroonian women and assess their anaemic status. Design: Longitudinal study. Setting: Buea Integrated Health Centre, Muea Health Centre, Mutengene Integrated Health Centre and the University of Buea Life Sciences ...

  3. Intestinal intussusception due to concurrent infections with ...

    African Journals Online (AJOL)

    The rat was anorexic and depressed with rough hair coat, and died before the commencement of the experiment. Grossly, the intussusception was 7 cm in length and 27 cm caudal to the stomach and 81cm to the ileo-caecal junction. The affected part of the small intestine was moderately distended with worms and the ...

  4. Knowledge based assessment of intestinal parasitic Infections ...

    African Journals Online (AJOL)

    There is an apparent lack of information on the risk and clinical symptoms of Intestinal Parasitic Infections (IPIs) among students attending boarding secondary schools in Ebonyi State, Nigeria. This questionnaire-based survey attempts to assess some behavioural habits, possible risk factor(s) as well as clinical symptoms ...

  5. intestinal helminthiasis among malnourished school age children

    African Journals Online (AJOL)

    Government Area to determine the prevalence rate of intestinal hjelminth infection among malnourished school children. Stool samples and finger prick blood .... in both male and female school children compared with a marked depreciation clue to the .... -rnalnutrition among India children. He submitted that control of such ...

  6. Intestinal Infarctus following Dilatation and Uterine Curettage

    Directory of Open Access Journals (Sweden)

    N.M. Ngowe

    2007-03-01

    Full Text Available We present a case of intestinal infarctus through the vagina. This was a consequence of induced abortion done clandestinely. The main objective was to point out the surgical complications of uterine dilatation and curettage by means of this rare case.

  7. Therapeutic hypothermia reduces intestinal ischemia/reperfusion ...

    African Journals Online (AJOL)

    To investigate the effects of therapeutic hypothermia (TH) on the morphology and function of intestine after cardiac arrest and resuscitation, 45 male rats were randomly assigned into three groups: (1) normothermia group, animals underwent ventricular fibrillation (VF) and cardiopulmonary resuscitation (CPR) with the rectal ...

  8. Mucin dynamics in intestinal bacterial infection.

    Directory of Open Access Journals (Sweden)

    Sara K Lindén

    Full Text Available Bacterial gastroenteritis causes morbidity and mortality in humans worldwide. Murine Citrobacter rodentium infection is a model for gastroenteritis caused by the human pathogens enteropathogenic Escherichia coli and enterohaemorrhagic E. coli. Mucin glycoproteins are the main component of the first barrier that bacteria encounter in the intestinal tract.Using Immunohistochemistry, we investigated intestinal expression of mucins (Alcian blue/PAS, Muc1, Muc2, Muc4, Muc5AC, Muc13 and Muc3/17 in healthy and C. rodentium infected mice. The majority of the C. rodentium infected mice developed systemic infection and colitis in the mid and distal colon by day 12. C. rodentium bound to the major secreted mucin, Muc2, in vitro, and high numbers of bacteria were found in secreted MUC2 in infected animals in vivo, indicating that mucins may limit bacterial access to the epithelial surface. In the small intestine, caecum and proximal colon, the mucin expression was similar in infected and non-infected animals. In the distal colonic epithelium, all secreted and cell surface mucins decreased with the exception of the Muc1 cell surface mucin which increased after infection (p<0.05. Similarly, during human infection Salmonella St Paul, Campylobacter jejuni and Clostridium difficile induced MUC1 in the colon.Major changes in both the cell-surface and secreted mucins occur in response to intestinal infection.

  9. intestinal helminth infections among pregnant cameroonian women

    African Journals Online (AJOL)

    East African Medical Journal Vol. 88 No. 11 November 2011. INTESTINAL HELMINTH ... The pregnant women received mebendazole and iron tablets on the day of enrollment at the antenatal clinic to control helminth ... malnutrition, vitamin A deficiency, diarrhoea and iron-deficiency anaemia (3,1). Pregnant women and.

  10. Metabolic complications in the small intestine syndrome

    International Nuclear Information System (INIS)

    Mora, Rafael; Orozco, Reynaldo

    2000-01-01

    Metabolic complications in the syndrome of small intestine is presented in a patient of masculine sex, 27 years old, who consulted for a square of inflammation gingival, migraine, fever, anorexia and adinamia for three days, followed by maculopapular-eritematose eruption for 8 days, coincident with the ampicillin ingestion, and later on severe abdominal pain and diarrhea

  11. Therapeutic hypothermia reduces intestinal ischemia/reperfusion ...

    African Journals Online (AJOL)

    Jane

    2011-07-25

    Jul 25, 2011 ... diamine oxidase (DAO) and apoptosis rate of intestinal epithelial cells were tested by ELISA and flow cytometry, respectively. ... The interruption and restoration of blood flow, induced by. *Corresponding author. ... intubated with a 14-gauge cannula (Abbocath-T, Abbott Hospital. Products Division; North ...

  12. Temporary intestinal ischemia for radiation protection

    International Nuclear Information System (INIS)

    Lote, K.

    1983-01-01

    The most important determinant of cellular radiosensivity is the tissue oxygen content at the time of irradiation. The purpose of the present experimental work was to assess a new iscemia-inducing method in order to reduce normal tissue radiation damage during radiotherapy. Temporary ischemia was induced in a cat small intestine by degraded starch microspheres. Regional arterial and tissue blod flow immediately fell by 85% with subsequent normalization within 26 minutes after microsphere injection. No tendency of small vessel thrombosis caused by starch sphere embolization in combination with previous or current intestinal irradiation was detected. Starch sphere remenants were rapidly engulfed by, and persisted within tissue macrophages for 14 days without causing intestinal inflammatory reactions. In vitro studies showed that human platelets neither adhered to nor were aggregated by starch microspheres. The new method, wich occlude arteriolar vessels distal to the mesentric arterial arcades and thus largely excludes collateral blood flow, seems suited to provide effictive and selective feline small intestinal hypoxic radiation protection. This conclusion may also be valid in man

  13. Faecalibacterium prausnitzii and human intestinal health

    NARCIS (Netherlands)

    Miquel, S.; Martin, R.; Rossi, O.; Bermudez-Humaran, L.G.; Chatel, J.M.; Sokol, H.; Thomas, M.; Wells, J.M.; Langella, P.

    2013-01-01

    Faecalibacterium prausnitzii is the most abundant bacterium in the human intestinal microbiota of healthy adults, representing more than 5% of the total bacterial population. Over the past five years, an increasing number of studies have clearly described the importance of this highly metabolically

  14. Intestinal colonisation, microbiota and future probiotics

    NARCIS (Netherlands)

    Salminen, S.; Benno, Y.; Vos, de W.M.

    2006-01-01

    The human intestine is colonized by a large number of microorganisms, collectively termed microbiota, which support a variety of physiological functions. As the major part of the microbiota has not yet been cultured, molecular methods are required to determine microbial composition and the impact of

  15. Intestinal obstruction in germ-free dogs.

    Science.gov (United States)

    Heneghan, J B; Robinson, J W; Menge, H; Winistörfer, B

    1981-08-01

    Mechanical occlusions were created in the intestines of four germ-free dogs. At the time of the operation, a control loop of mid-intestine was perfused in vivo and then excised for examinations in vitro, which included the determination of the equilibrium uptake of phenylalanine and of beta-methyl-glucoside, the influx kinetics of phenylalanine and morphometric analysis of the mucosa by microdissection and stereological techniques. Seven days after establishment of the occlusion the abdomen was reopened, and loops above and below the occlusion were perfused, and then excised for the same tests in vitro. Unlike occluded loops of conventional dogs, the intestine of the germ-free animal above the occlusion does not secrete water and electrolytes into the lumen. Its transport properties in vitro do not differ from those of the control loop, and the morphometric analyses reveal only slight changes in villus structure. The loop below the obstruction undergoes marked atrophy, as has been observed in conventional dogs. The results suggest that the copious secretion that occurs above an intestinal obstruction in normal animals is due to the presence of an abundant bacterial population in the obstruction fluid.

  16. Temporal changes in the intestinal growth promoting effects of glucagon-like peptide 2 following intestinal resection

    DEFF Research Database (Denmark)

    Kaji, Tatsuru; Tanaka, Hiroaki; Redstone, Heather

    2008-01-01

    BACKGROUND: We investigated the effects of variations in the postresection timing of glucagon-like peptide-2 (GLP-2) administration on intestinal morphology and activity. METHODS: A rat model of 90% intestinal resection (SBR) with exclusively parenteral nutritional (TPN) was used. Early versus late...... that the intestinal adaptive and growth promoting actions of GLP-2 may be mediated by non-neuronal effector pathways. Although further studies are required, early treatment with GLP-2 following resection may maximize intestinal growth....

  17. Effects of Digested Onion Extracts on Intestinal Gene Expression: An Interspecies Comparison Using Different Intestine Models.

    Directory of Open Access Journals (Sweden)

    Nicole J W de Wit

    Full Text Available Human intestinal tissue samples are barely accessible to study potential health benefits of nutritional compounds. Numbers of animals used in animal trials, however, need to be minimalized. Therefore, we explored the applicability of in vitro (human Caco-2 cells and ex vivo intestine models (rat precision cut intestine slices and the pig in-situ small intestinal segment perfusion (SISP technique to study the effect of food compounds. In vitro digested yellow (YOd and white onion extracts (WOd were used as model food compounds and transcriptomics was applied to obtain more insight into which extent mode of actions depend on the model. The three intestine models shared 9,140 genes which were used to compare the responses to digested onions between the models. Unsupervised clustering analysis showed that genes up- or down-regulated by WOd in human Caco-2 cells and rat intestine slices were similarly regulated by YOd, indicating comparable modes of action for the two onion species. Highly variable responses to onion were found in the pig SISP model. By focussing only on genes with significant differential expression, in combination with a fold change > 1.5, 15 genes showed similar onion-induced expression in human Caco-2 cells and rat intestine slices and 2 overlapping genes were found between the human Caco-2 and pig SISP model. Pathway analyses revealed that mainly processes related to oxidative stress, and especially the Keap1-Nrf2 pathway, were affected by onions in all three models. Our data fit with previous in vivo studies showing that the beneficial effects of onions are mostly linked to their antioxidant properties. Taken together, our data indicate that each of the in vitro and ex vivo intestine models used in this study, taking into account their limitations, can be used to determine modes of action of nutritional compounds and can thereby reduce the number of animals used in conventional nutritional intervention studies.

  18. Exploring food effects on indinavir absorption with human intestinal fluids in the mouse intestine.

    Science.gov (United States)

    Holmstock, Nico; De Bruyn, Tom; Bevernage, Jan; Annaert, Pieter; Mols, Raf; Tack, Jan; Augustijns, Patrick

    2013-04-11

    Food can have a significant impact on the pharmacokinetics of orally administered drugs, as it may affect drug solubility as well as permeability. Since fed state conditions cannot easily be implemented in the presently available permeability tools, including the frequently used Caco-2 system, exploring food effects during drug development can be quite challenging. In this study, we investigated the effect of fasted and fed state conditions on the intestinal absorption of the HIV protease inhibitor indinavir using simulated and human intestinal fluids in the in situ intestinal perfusion technique in mice. Although the solubility of indinavir was 6-fold higher in fed state human intestinal fluids (FeHIF) as compared to fasted state HIF (FaHIF), the intestinal permeation of indinavir was 22-fold lower in FeHIF as compared to FaHIF. Dialysis experiments showed that only a small fraction of indinavir is accessible for absorption in FeHIF due to micellar entrapment, possibly explaining its low intestinal permeation. The presence of ritonavir, a known P-gp inhibitor, increased the intestinal permeation of indinavir by 2-fold in FaHIF, while there was no increase when using FeHIF. These data confirm that drug-food interactions form a complex interplay between solubility and permeability effects. The use of HIF in in situ intestinal perfusions holds great promise for biorelevant absorption evaluation as it allows to directly explore this complex solubility/permeability interplay on drug absorption. Copyright © 2013 Elsevier B.V. All rights reserved.

  19. Fish oil enhances recovery of intestinal microbiota and epithelial integrity in chronic rejection of intestinal transplant.

    Directory of Open Access Journals (Sweden)

    Qiurong Li

    Full Text Available BACKGROUND: The intestinal chronic rejection (CR is the major limitation to long-term survival of transplanted organs. This study aimed to investigate the interaction between intestinal microbiota and epithelial integrity in chronic rejection of intestinal transplantation, and to find out whether fish oil enhances recovery of intestinal microbiota and epithelial integrity. METHODS/PRINCIPAL FINDINGS: The luminal and mucosal microbiota composition of CR rats were characterized by DGGE analysis at 190 days after intestinal transplant. The specific bacterial species were determined by sequence analysis. Furthermore, changes in the localization of intestinal TJ proteins were examined by immunofluorescent staining. PCR-DGGE analysis revealed that gut microbiota in CR rats had a shift towards Escherichia coli, Bacteroides spp and Clostridium spp and a decrease in the abundance of Lactobacillales bacteria in the intestines. Fish oil supplementation could enhance the recovery of gut microbiota, showing a significant decrease of gut bacterial proportions of E. coli and Bacteroides spp and an increase of Lactobacillales spp. In addition, CR rats showed pronounced alteration of tight junction, depicted by marked changes in epithelial cell ultrastructure and redistribution of occuldin and claudins as well as disruption in TJ barrier function. Fish oil administration ameliorated disruption of epithelial integrity in CR, which was associated with an improvement of the mucosal structure leading to improved tight junctions. CONCLUSIONS/SIGNIFICANCE: Our study have presented novel evidence that fish oil is involved in the maintenance of epithelial TJ integrity and recovery of gut microbiota, which may have therapeutic potential against CR in intestinal transplantation.

  20. Effects of Digested Onion Extracts on Intestinal Gene Expression: An Interspecies Comparison Using Different Intestine Models.

    Science.gov (United States)

    de Wit, Nicole J W; Hulst, Marcel; Govers, Coen; van der Meulen, Jan; van Hoef, Angeline; Stoopen, Geert; Hamers, Astrid; Hoekman, Arjan; de Vos, Ric; Bovee, Toine F H; Smits, Mari; Mes, Jurriaan J; Hendriksen, Peter J M

    2016-01-01

    Human intestinal tissue samples are barely accessible to study potential health benefits of nutritional compounds. Numbers of animals used in animal trials, however, need to be minimalized. Therefore, we explored the applicability of in vitro (human Caco-2 cells) and ex vivo intestine models (rat precision cut intestine slices and the pig in-situ small intestinal segment perfusion (SISP) technique) to study the effect of food compounds. In vitro digested yellow (YOd) and white onion extracts (WOd) were used as model food compounds and transcriptomics was applied to obtain more insight into which extent mode of actions depend on the model. The three intestine models shared 9,140 genes which were used to compare the responses to digested onions between the models. Unsupervised clustering analysis showed that genes up- or down-regulated by WOd in human Caco-2 cells and rat intestine slices were similarly regulated by YOd, indicating comparable modes of action for the two onion species. Highly variable responses to onion were found in the pig SISP model. By focussing only on genes with significant differential expression, in combination with a fold change > 1.5, 15 genes showed similar onion-induced expression in human Caco-2 cells and rat intestine slices and 2 overlapping genes were found between the human Caco-2 and pig SISP model. Pathway analyses revealed that mainly processes related to oxidative stress, and especially the Keap1-Nrf2 pathway, were affected by onions in all three models. Our data fit with previous in vivo studies showing that the beneficial effects of onions are mostly linked to their antioxidant properties. Taken together, our data indicate that each of the in vitro and ex vivo intestine models used in this study, taking into account their limitations, can be used to determine modes of action of nutritional compounds and can thereby reduce the number of animals used in conventional nutritional intervention studies.

  1. Transplante de intestino delgado Small intestine transplantation

    Directory of Open Access Journals (Sweden)

    Flávio Henrique Ferreira Galvão

    2003-06-01

    Full Text Available RACIONAL: Avanços da biotecnologia e o desenvolvimento de novas drogas imunossupressoras melhoraram os resultados do transplante de intestino delgado. Esse transplante é atualmente indicado para casos especiais da falência intestinal. OBJETIVO: A presente revisão realça os recentes desenvolvimentos na área do transplante de intestino delgado. MATERIAL E MÉTODO: Mais de 600 publicações de transplante de intestino delgado foram revisadas. O desenvolvimento da pesquisa, novas estratégias de imunossupressão, monitorização do enxerto e do receptor, e avanços na técnica cirúrgica são discutidos. RESULTADOS: Realizaram-se cerca de 700 transplante de intestino delgado em 55 centros: 44% intestino-fígado, 41% enxerto intestinal isolado e 15% transplante multivisceral. Rejeição e infecção são as principais limitações desse transplante. Sobrevida de 5 anos na experiência internacional é de 46% para o transplante de intestino isolado, 43% para o intestino-fígado e de cerca de 30% para o transplante multivisceral. Sobrevidas prolongadas são mais freqüentes nos centros com maior experiência. Em série de 165 transplantes intestinais na Universidade de Pittsburgh, PA, EUA, foi relatada sobrevida do paciente maior do que 75% no primeiro ano, 54% em 5 anos e 42% em 10 anos. Mais de 90% desses pacientes assumem dieta oral irrestrita. CONCLUSÃO: O transplante de intestino delgado evoluiu de estratégia experimental para uma alternativa viável no tratamento da falência intestinal permanente. Promover o refinamento da terapia imunossupressora, do manejo e prevenção de infecções, da técnica cirúrgica e da indicação e seleção adequada dos pacientes é crucial para melhorar a sobrevida desse transplante.BACKGROUND: Significant progress has been made in clinical small bowel transplantation over the last decade mainly due advances in biotechnology and new immunosuppressive regiments. This transplantation has now been indicated

  2. Seguimiento de un proceso de fermentación en una bodega del Penedés

    OpenAIRE

    Carrillo Pujante, Míriam

    2007-01-01

    El proyecto trata del proceso de elaboración del vino, concretamente del proceso de fermentación alcohólica. Dicho proceso tiene una gran importancia ya que durante éste es cuando se produce la transformación del azúcar en alcohol mediante levaduras. Durante la fermentación alcohólica hay que realizar una serie de controles, análisis, para ver si dicho proceso sigue en marcha o se ha parado. Y además, los análisis son para comprobar que los parámetros como la acidez, ...

  3. Ejecución y monitoreo de procesos de negocios distribuidos entre diferentes motores de Bonita OS

    OpenAIRE

    Karabogosian, Leonardo Damián; Bazán, Patricia; Martínez Garro, José Nicolás

    2014-01-01

    La combinación de las tecnologías asociadas a Cloud Computing y BPM (Business Process Management) modifica aspectos tanto de diseño como de ejecución de los procesos de negocios. Los ambientes distribuidos en el contexto de los procesos favorecen el rendimiento y proponen incorporar el concepto de descomposición de procesos, permitiendo que los mismos se ejecuten tanto en un entorno cloud o embebido. Si bien la descomposición de procesos es un tema abordado en los últimos años, el monit...

  4. La protección del menor en el proceso judicial de prodigalidad. La protección del menor en el proceso judicial de prodigalidad *.

    Directory of Open Access Journals (Sweden)

    Sonia Calaza López

    2011-09-01

    Full Text Available En este ensayo se analiza la posible reinvención del proceso de prodigalidad desde la perspectiva de la protección de los menores. En este sentido, proponemos la regulación de un proceso de prodigalidad ágil, dinámico, eficaz, sencillo y económico, que, sin merma de garantías procesales, otorgue, en breve espacio de tiempo, adecuada satisfacción a las necesidades de los alimentistas frente a sus alimentantes.In this test there is analyzed the possible reinvention of the process of prodigality from the perspective of the protection of the minors. In this respect, we propose the regulation of a process, dynamic, effective, simple and economic of agile prodigality, that, without wastage of procedural guarantees, it grants, shortly lapse of time, suitable satisfaction to the needs of the alimentistas opposite to his alimentantes.

  5. [The complications of intestinal stoma in children].

    Science.gov (United States)

    Minaev, S V; Bykov, N I; Isaeva, A V; Kachanov, A V; Tovkan, E A; Filip'yeva, N V; Gerasimenko, I N

    To investigate the complications of intestinal stoma in children and to develop measures for decrease of their incidence. The study included 152 children with congenital and acquired gastrointestinal pathology requiring surgical treatment with the imposition of intestinal stoma. Atresia of intestinal tube was observed in 28 (18.4%) children, meconium ileus - in 10 (6.6%) cases, Hirschsprung's disease - in 11 (7.2%)cases, anorectal malformations - in 39 (25.7%) cases, multiple malformations - in 11 (7.2%) patients, necrotic enterocolitis - in 56 (36.8%) patients, other reasons - in 7 (4.6%) cases. The average age of patients was 12,3±7,2 days. There were 93 (61.2%) boys and 59 (38.8%) girls. Ileostomy, ileocolostomy and colostomy were made in 37 (24.3%), 46 (30.3%) and 69 (45.4%) cases respectively. Time of intestinal stoma function was 18-217 days. Early complications were dehiscence in the area of stoma in 4 (2.6%) children, evagination in 7 (4.6%) patients, marginal necrosis of stoma in 2 (1.3%) cases, retraction of stomy into abdominal cavity in 1 (0.6%) child and abdominal skin maceration in 8 (5.2%) patients. Remote complications included dermatitis around stomy in 35 (23.1%) children, stenosis of stoma in 9 (5.9%) cases, evagination of stoma in 12 (7.9%) patients. Also, 5 patients were unable to use the colostomy bag due to vicious overlaying of intestinal stoma. Using the colostomy bags «Coloplast» and skin care products around the stoma significantly reduced (pstoma depends on not only technical aspects but also obligatory care performance with timely correction of complications.

  6. Role of Smooth Muscle in Intestinal Inflammation

    Directory of Open Access Journals (Sweden)

    Stephen M Collins

    1996-01-01

    Full Text Available The notion that smooth muscle function is altered in inflammation is prompted by clinical observations of altered motility in patients with inflammatory bowel disease (IBD. While altered motility may reflect inflammation-induced changes in intrinsic or extrinsic nerves to the gut, changes in gut hormone release and changes in muscle function, recent studies have provided in vitro evidence of altered muscle contractility in muscle resected from patients with ulcerative colitis or Crohn’s disease. In addition, the observation that smooth muscle cells are more numerous and prominent in the strictured bowel of IBD patients compared with controls suggests that inflammation may alter the growth of intestinal smooth muscle. Thus, inflammation is associated with changes in smooth muscle growth and contractility that, in turn, contribute to important symptoms of IBD including diarrhea (from altered motility and pain (via either altered motility or stricture formation. The involvement of smooth muscle in this context may be as an innocent bystander, where cells and products of the inflammatory process induce alterations in muscle contractility and growth. However, it is likely that intestinal muscle cells play a more active role in the inflammatory process via the elaboration of mediators and trophic factors, including cytokines, and via the production of collagen. The concept of muscle cells as active participants in the intestinal inflammatory process is a new concept that is under intense study. This report summarizes current knowledge as it relates to these two aspects of altered muscle function (growth and contractility in the inflamed intestine, and will focus on mechanisms underlying these changes, based on data obtained from animal models of intestinal inflammation.

  7. Determination of Intestine Inflammation Markers in Diagnostic Search in Children with Intestinal Diseases

    Directory of Open Access Journals (Sweden)

    N.V. Pavlenko

    2016-08-01

    Full Text Available Introduction. Prevalence of bowel diseases in children is the second, trailing only the diseases of gastroduodenal zone and growing in recent years. Actual one is the problem of differential diagnosis of functional and inflammatory intestinal diseases using non-invasive methods on the prehospital stage and as a screening. Objective. Comparative analysis of fecal markers of the bowel inflammation (lactoferrine and calprotectine with endoscopy and morphology of intestinal mucosa in children. Matherials and methods. 49 children aged 6–18 years were examined. All patients underwent endoscopic and morphological study of the intestine, coprotest, determination of fecal markers of bowel inflammation (lactoferrin and calprotectine. Results. It is shown that in young children, the intestinal mucosa mainly hadn’t endoscopic changes, coprotest and morphological examination didn’t reveal the signs of inflammation, fecal intestinal inflammation markers were negative (p < 0.05. In the group of older children, moderate or marked catarrhal changes were found endoscopically, coprotest results were typical of inflammation in the intestines, it was morphologically proved the presence of chronic inflammation of the mucous membrane of the colon with signs of atrophy, the results of lactoferrin and calprotectine determination were positive (p < 0.05. Conclusion. The findings suggest that the evaluation of calprotectine and lactoferrin can be used in pediatric patients because of its non-invasiveness as diagnostic screening for the selection of patients for the further endoscopic examination and diagnostic search.

  8. MEMORIAS DEL TRABAJO ANTE LOS PROCESOS DE PRIVATIZACIÓN EN ARGENTINA

    Directory of Open Access Journals (Sweden)

    Hernán Palermo

    2011-01-01

    Full Text Available El objetivo del artículo es analizar de qué modo los procesos de privatización en Argentina implicaron la desestructuración de un orden sociolaboral y simbólico, que organizaba la vida de dos colectivos de trabajadores vinculados con la extracción de petróleo y la producción de acero. Realiza una reflexión sobre los sentidos y valores que se diputan en los procesos de construcción de la memoria, rastreando continuidades y rupturas. Como común denominador encuentra que el proceso privatizador, así como la conversión de los trabajadores en emprendedores, representa un punto de ruptura que dificulta y complejiza la transmisión de la experiencia.

  9. Procesos iniciales de lecto-escritura en el nivel de educación inicial

    Directory of Open Access Journals (Sweden)

    Chaves Salas, Ana Lupita

    2002-06-01

    Full Text Available El análisis de los procesos iniciales de lecto-escritura, propósito de este artículo, parte de una descripción de la función de la educación inicial y de cómo en este nivel se han incentivado dichos procesos. Posteriormente, se estudia la apropiación de la lengua escrita por parte de la niña y el niño, concebida como un proceso constructivo, interactivo y de producción cultural. Finalmente, se hacen algunas reflexiones con el fin de provocar la discusión en torno a este tema entre las personas interesadas, y así, contribuir a la transformación del nivel inicial del sistema educativo costarricense.

  10. Los procesos iniciales de lecto-escritura en el nivel de educación inicia

    Directory of Open Access Journals (Sweden)

    Ana Lupita Chaves Salas

    2002-01-01

    Full Text Available El análisis de los procesos iniciales de lecto-escritura, propósito de este artículo, parte de una descripción de la función de la educación inicial y de cómo en este nivel se han incentivado dichos procesos. Posteriormente, se estudia la apropiación de la lengua escrita por parte de la niña y el niño, concebida como un proceso constructivo, interactivo y de producción cultural. Finalmente, se hacen algunas reflexiones con el fin de provocar la discusión en torno a este tema entre las personas interesadas, y así, contribuir a la transformación del nivel inicial del sistema educativo costarricense.

  11. Estudio de ventajas energéticas en un proceso de destilación

    Directory of Open Access Journals (Sweden)

    Carlos Ariel Cardona Alzate

    2013-04-01

    Full Text Available Este trabajo desarrolla un método para comparar los gastos energéticos entre las configuraciones secuencial (reacción-separación y simultánea (destilación reactiva, analizando los flujos internos y externos de un proceso. Como ejemplo se utilizó una reacción tipo: A + B D C + D; con temperaturas de saturación: TCσprocesos convencionales para este tipo de procesos.

  12. Precision cut intestinal slices are an appropriate ex vivo model to study NSAID-induced intestinal toxicity in rats

    NARCIS (Netherlands)

    Niu, Xiaoyu; de Graaf, Inge A. M.; van der Bij, Hendrik A.; Groothuis, Geny M. M.

    2014-01-01

    Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used therapeutic agents, however, they are associated with a high prevalence of intestinal side effects. In this investigation, rat precision cut intestinal slices (PCIS) were evaluated as an ex vivo model to study NSAID-induced intestinal

  13. Alternative Functional In Vitro Models of Human Intestinal Epithelia

    Directory of Open Access Journals (Sweden)

    Amanda L Kauffman

    2013-07-01

    Full Text Available Physiologically relevant sources of absorptive intestinal epithelial cells are crucial for human drug transport studies. Human adenocarcinoma-derived intestinal cell lines, such as Caco-2, offer conveniences of easy culture maintenance and scalability, but do not fully recapitulate in vivo intestinal phenotypes. Additional sources of renewable physiologically relevant human intestinal cells would provide a much needed tool for drug discovery and intestinal physiology. We sought to evaluate and compare two alternative sources of human intestinal cells, commercially available primary human intestinal epithelial cells (hInEpCs and induced pluripotent stem cell (iPSC-derived intestinal cells to Caco-2, for use in in vitro transwell monolayer intestinal transport assays. To achieve this for iPSC-derived cells, our previously described 3-dimensional intestinal organogenesis method was adapted to transwell differentiation. Intestinal cells were assessed by marker expression through immunocytochemical and mRNA expression analyses, monolayer integrity through Transepithelial Electrical Resistance (TEER measurements and molecule permeability, and functionality by taking advantage the well-characterized intestinal transport mechanisms. In most cases, marker expression for primary hInEpCs and iPSC-derived cells appeared to be as good as or better than Caco-2. Furthermore, transwell monolayers exhibited high TEER with low permeability. Primary hInEpCs showed molecule efflux indicative of P-glycoprotein transport. Primary hInEpCs and iPSC-derived cells also showed neonatal Fc receptor-dependent binding of immunoglobulin G variants. Primary hInEpCs and iPSC-derived intestinal cells exhibit expected marker expression and demonstrate basic functional monolayer formation, similar to or better than Caco-2. These cells could offer an alternative source of human intestinal cells for understanding normal intestinal epithelial physiology and drug transport.

  14. Propuesta de un proceso de enseñanza-aprendizaje para la asignatura Diseño de Software como proceso de software

    Directory of Open Access Journals (Sweden)

    Lund, María Inés

    2014-04-01

    Full Text Available La cátedra Diseño de Software se dicta actualmente en 4º año de las carreras del Departamento de Informática de la Facultad de Ciencias Exactas, Físicas y Naturales (FCEFN de la Universidad Nacional de San Juan (UNSJ. Esta materia se enfoca principalmente al Diseño Orientado a Objetos (DOO, brindando conceptos y conocimientos desarrollados en forma teórica y con un fuerte componente práctico, de todos los diagramas de modelado de software que provee el Lenguaje de Modelado Unificado (UML, con el fin de comprender acabadamente el objetivo que se persigue con cada uno de ellos y en qué casos es conveniente o útil aplicarlos. El presente trabajo se sustenta de la experiencia adquirida en la práctica aplicada para la enseñanza de DOO, utilizando UML para el modelado, donde las actividades prácticas abarcan desde el análisis hasta llegar a una propuesta de diseño de implementación. Se presenta un modelo de proceso de enseñanza aprendizaje, como proceso de software, y los artefactos utilizados para guiar al alumno en la resolución de un problema de desarrollo de software específico, utilizando para su especificación el lenguaje de metamodelado de procesos SPEM 2.0 y para generar el modelado del proceso de software la herramienta Eclipse Process Framework Composer (EPFC.

  15. UN MÉTODO PARA LA TRAZABILIDAD DE REQUISITOS EN EL PROCESO UNIFICADO DE DESARROLLO

    Directory of Open Access Journals (Sweden)

    Marta Silvia Tabares

    2007-12-01

    Full Text Available El Proceso Unificado es un proceso de desarrollo adoptado por gran parte de las empresas desarrolladoras de software. Esto lleva a que atributos de calidad como la trazabilidad de requisitos deban estandarizarse para este proceso, con el fin de lograr los niveles de calidad exigidos por los clientes. Por lo general, los modelos de trazabilidad se proponen independientemente del proceso o métodos de desarrollo, y su definición y mantenimiento dependen de los criterios de calidad usados por los desarrolladores. En este artículo se presenta un método para la práctica de la trazabilidad en el Proceso Unificado de Desarrollo. El enfoque propone un flujo de trabajo para el control y soporte a la trazabilidad en las iteraciones del proceso. Dicho flujo establece un conjunto de acciones para generar modelos de trazabilidad que faciliten negociaciones oportunas con los participantes del proyecto.Unified Process is the development process adopted by many software development companies. Quality attributes, such as requirement traceability, must be standardized for this process, so that the system can achieve the quality demanded by customers. Commonly, traceability models are proposed independently of either the development process or the methodology that are followed, and its definition and maintenance depends on the quality criteria used by the developers. A traceability method for the Unified Development Process is presented in this paper. This approach proposes a workflow to control and support traceability throughout the iterations of the process. This workflow establishes a set of actions capable of generating traceability models that facilitate opportune agreement with the customers.

  16. Herramienta para establecer y controlar Iniciativas de Mejora de Procesos con MoProSoft

    Directory of Open Access Journals (Sweden)

    Dagoberto Cruz Sandoval

    2015-02-01

    Full Text Available La mejora de procesos software es una disciplina cuya premisa es que un proceso de calidad tiene como consecuencia lógica un producto software de calidad. En México, una industria software emergente y compuesta en su mayoría por micro y pequeñas empresas, ha empezado a incursionar en este tipo de disciplina utilizando el modelo mexicano de mejora de procesos conocido como MoProSoft, sin embargo la carencia de conocimiento y experiencia, hace de este tipo de proyectos algo complicado y desgastante. En el presente trabajo se presenta el desarrollo de un marco de trabajo para las micro y pequeñas empresas desarrolladoras de software en México, el cual es apoyado por una herramienta llamada Kaizen que automatiza las fases básicas de una mejora de procesos: compromiso, evaluación, planeación e implementación basadas en los procesos, actividades, prácticas y roles definidos en MoProSoft. La herramienta tiene como objetivo principal proporcionar apoyo a las micro empresas en las iniciativas de mejora por medio de un marco de actividades automatizadas que guían sus pasos durante la ejecución del programa de mejora. Además, se presenta un caso de estudio y resultados cuantitativos de que con el uso de Kaizen cuatro micro empresas mexicanas vieron mejorados sus procesos de desarrollo de software instaurando las prácticas efectivas definidas por MoProSoft.

  17. ESTUDIO COMPARATIVO DE MODELOS DE GESTIÓN DEL PROCESO DE DESARROLLO DE PRODUCTOS ALIMENTICIOS

    OpenAIRE

    G. Rossetti; L. Arcusin; F. Giraudo; P. Murer

    2014-01-01

    Debido al aumento de los productos ofrecidos en el mercado y a la reducción del tiempo de vida de los mismos, el Proceso de Desarrollo de Productos (PDP) es considerado un proceso de negocio cada vez más importante para la competitividad de las empresas. Los productos deben gestionarse de modo que se introduzcan rápidamente en el mercado, satisfagan mejor las necesidades de los clientes, sean más fáciles de fabricar, resulten atractivos en el mercado y aseguren beneficios para las empresas. D...

  18. DIMENSIONES TEÓRICAS DE LOS PROCESOS DE INNOVACIÓN CURRICULAR

    OpenAIRE

    Nápoli, Fernando Pablo; Tilli, Patricia; Gómez, Teresa; Peralta, Azucena; Acosta, Viviana

    2013-01-01

    El presente trabajo tiene como objetivo abordar desde una perspectiva crítica y analítico-descriptiva, cuestiones vinculadas al planeamiento de la educación superior en general y a los procesos de innovación curricular en particular. Partimos desde marcos teóricos específicos de dichos procesos, articulando sobre estas teorías, las experiencias desde una mirada macro y desde la gestión académica. En primera instancia se analiza la posible aparición de tensiones entre las sig...

  19. Neurobiología de la memoria y procesos neuroquímicos implicados

    OpenAIRE

    Marilia Baquerizo Sedano; Jhonatan Astucuri Hidalgo

    2012-01-01

    Desde el paradigma de la evolución, el aprendizaje y la memoria actúan como medio principal de adaptación de los seres vivos a las modificaciones inciertas del medio ambiente (1), he ahí su importancia. Ambos procesos tienen una relación íntima y a decir verdad, no es posible distinguirlos dentro del circuito neuronal (2). Se asume, sin embargo, con fines académicos, que el aprendizaje es el proceso de adquisición de información y la memoria se refiere a la codificación, almacenamiento y recu...

  20. Determinantes de la innovación en productos o procesos: el caso colombiano

    OpenAIRE

    Germán Daniel Lambardi; Jhon James Mora

    2014-01-01

    Este artículo analiza empíricamente los determinantes de las decisiones sobre innovación de las firmas manufactureras colombianas. En particular, estudia la posibilidad de que exista algún grado de dependencia entre la innovación en productos y en procesos. Estima un modelo probit bivariado utilizando datos de la segunda Encuesta de Desarrollo e Innovación Tecnológica. Los resultados indican que existe una fuerte complementariedad entre la innovación en productos y procesos.

  1. Los Sistemas Gestores de Flujos de Trabajo en la Gestión de Procesos Software

    Directory of Open Access Journals (Sweden)

    Víctor Hugo Menéndez Domínguez

    2016-11-01

    Full Text Available Hoy en día, las empresas de software se ven obligadas a mejorar su rendimiento para poder sobrevivir en un entorno altamente competitivo: los clientes demandan una mayor calidad, menor plazo de entrega, mejor servicio, atención personalizada, etc. En este trabajo se describen a los procesos software así como los flujos de trabajo. Su combinación y automatización mejora el flujo de información asociado a las actividades de dichos procesos, lo que facilita el control y permite mejorar el rendimiento, reducir costos y plazos, minimizar errores y garantiza una mayor calidad, entre otras ventajas.

  2. Simulación de procesos de producción robotizados mediante el programa Robotstudio

    OpenAIRE

    Martínez León, Víctor

    2008-01-01

    El proyecto fin de carrera está encuadrado dentro del proyecto colaborativo de investigación europeo ManuBuild, adscrito al Sexto Programa Marco de la Comisión Europea, que tiene una duración de 4 años (2005-2009). El proyecto aborda el posible cambio en la filosofía de la construcción del enfoque actual a un proceso más integrado, abierto, eficiente y seguro teniendo como línea básica el paso a la industrialización de todo el proceso. Este documento se divide principalmente en tres bloques: ...

  3. El proceso de selección de talento humano bajo el enfoque de competencias

    OpenAIRE

    Moreira de Vélez, Janeth; Loor Zambrano, Halder; Velásquez Velásquez, María

    2013-01-01

    El proceso de selección de talento humano por competencias no es sólo una de las fases del modelo de gestión por competencias, si no la más importante de las etapas, justamente porque de éste proceso depende la efectividad del cumplimiento de los resultados en las distintas áreas de la organización, a saber, finanzas, talento humano, producción y operaciones, marketing, administración y hasta la propia área de talento humano. En el transcurso de esta investigación, se emplean técnicas como la...

  4. Relevancia e Inferencia: Procesos cognitivos propios de la comunicación humana

    Directory of Open Access Journals (Sweden)

    Constanza Moya Pardo

    2006-06-01

    Full Text Available Este artículo pretende mostrar los planteamientos cognitivos más representativos de la Teoría de la Relevancia propuesta por Spelber & Wilson con respecto al modelo ostensivo-inferencial. Este modelo plantea un mecanismo deductivo explícito que da cuenta de los procesos y estrategias que permiten el paso del significado literal a la interpretación pragmática de los mensajes en el proceso de comunicación humana.

  5. PROCESOS Y PROCEDIMIENTOS DE ORIENTACIÓN VOCACIONAL / PROFESIONAL / LABORAL DESDE UNA PERSPECTIVA SISTÉMICA

    OpenAIRE

    Ana Elvira Castañeda Cantillo; Julio Abel Niño Rojas

    2005-01-01

    Esta investigación buscó hacer una descripción de las comprensiones, estrategias y prácticas que identifican el proceso de orientación vocacional / profesional / laboral en la familia y la escuela. Para ello se identificaron los niveles de participación de cada uno de los actores de la organización escolar: estudiantes, docentes, orientadores y padres de familia, se evaluó el impacto de los procesos de orientación profesional, especificando las acciones que se realizan para ello y el papel de...

  6. Análisis del personal sanitario adecuado para realizar el proceso de triaje hospitalario

    OpenAIRE

    Ozámiz Monasterio, Nerea

    2014-01-01

    El proceso de triaje se puede definir como un proceso de valoración clínica preliminar, mediante el cual se ordenan a los pacientes antes de su correspondiente valoración diagnóstica y terapéutica. Existen diversos métodos de triaje en función del personal sanitario que lo realiza, pudiendo ser realizado por el personal de enfermería, por facultativos, por la combinación de ambos e incluso por cualquier persona del ámbito sanitario con una formación específica adecuada. El objetivo de...

  7. Estimación y control de procesos biotecnológicos multivariables

    OpenAIRE

    Nuñez, Sebastián

    2014-01-01

    La presente tesis doctoral aborda problemas de estimación y control de variables en procesos biotecnológicos. Se aportan soluciones novedosas a dos cuestiones relevantes para el control de estos procesos: i) el diseño de observadores (sensores virtuales) de variables no medibles a partir de las mediciones disponibles, y ii) el diseño de lazos de regulación del crecimiento en cultivos de microorganismos que utilizan múltiples sustratos. Con el objetivo de disponer de estimaciones de ...

  8. Evolución del proceso de titulación en España

    OpenAIRE

    Susana Blanco García; Pedro Carvajal Molina

    2001-01-01

    El proceso de titulización de activos es entendido como la transformación de derechos de crédito presentes y futuros en valores de renta fija negociables, dando de baja en el balance de las entidades cedentes los activos vendidos. Todo proceso de titulización conlleva la transformación de un conjunto de activos heterogéneos en cuanto a sus características financieras (valor nominal, intereses, índice de referencia, vencimiento, sistema de amortización, riesgo, etc.) en otro paquete de activos...

  9. Macro y micro-nutrientes que intervienen en el proceso de cicatrización

    OpenAIRE

    Pelayo Vergara, María

    2014-01-01

    La historia de las heridas y su curación es tan antigua como la historia de la humanidad. Ya en 1859 Florence Nightingale hacía referencia a la importancia de la dieta en la curación de las heridas. El objetivo de esta revisión bibliográfica sobre los macro y micronutrientes que intervienen en el proceso de cicatrización es identificar el conocimiento actual sobre el tema, analizando la influencia de los diversos nutrientes en el proceso de cicatrización de las heridas para ...

  10. Aportes para una vida saludable. Proceso socioeducativo con estudiantes de primer ingreso, Universidad Nacional

    OpenAIRE

    Gonzalez-Soto, L.; Orozco-Morales, A.R.

    2017-01-01

    Propósito: Exponer la experiencia de medir en algún grado el impacto social de un proceso socioeducativo anual, desarrollado con 800 estudiantes de primer ingreso provenientes de diversos lugares del país, con limitadas condiciones socioeconómica y quienes son beneficiarios de beca para sus estudios. El proceso consistió en establecer 4 o 5 eventos anuales y trabajar con metodologías lúdicas temas alusivos a estilos de vida saludables. Material y método: Se aplicó la técnica de grupo focal al...

  11. Procesos de Patrimonialización en el Arte Contemporáneo.

    OpenAIRE

    Gómez Redondo, Carmen

    2011-01-01

    Con este artículo se pretende iniciar un análisis sobre algunos conceptos relevantes dentro del ámbito de la educación patrimonial: identidad, patrimonio y arte contemporáneo, así como sobre las relaciones procesuales que los vinculan. Este trabajo forma parte del proceso de investigación de tesis: “Procesos de Patrimonialización en el Arte Contemporáneo”. Palabras clave: arte contemporáneo, cultura contemporánea, educación patrimonial, identidad cultural, categorías artísticas....

  12. Paraciclismo: estudio sobre los procesos de integración a nivel internacional

    OpenAIRE

    Pérez-Tejero, Javier; Blasco-Yago, María; González-Lázaro, Javier; García-Hernández, Juan; Soto-Rey, Javier; Coterón, Javier

    2013-01-01

    El Paraciclismo (o ciclismo adaptado) es una de las primeras modalidades deportivas adaptadas integradas en la federación internacional de su deporte correspondiente. Este deporte es un buen ejemplo a la hora de estudiar los procesos de integración en las federaciones unideportivas. El objetivo del estudio es analizar el grado de implantación de estos procesos en el ciclismo a nivel internacional y conocer los indicadores concretos que lo caracterizan. El estudio se llevó a cabo en el Campeon...

  13. La eficacia de la Prueba Indiciaria en el Proceso Penal Ecuatoriano

    OpenAIRE

    Pérez Medina, Lenin

    2007-01-01

    La eficacia de la prueba Indiciaria en el Proceso Penal Ecuatoriano, a tomado una nueva dimensión en nuestro sistema procesal, ya que a partir de la vigencia del nuevo Código de Procedimiento Penal, se ha orientado a garantizar la aplicación del debido proceso, en todos los parámetros que la constitución establece, en el presente trabajo estudiamos diferentes tópicos como presunción , sospecha , conjetura, vestigio, huella y rastro donde podría aparecer la prueba indiciaria, si...

  14. DESCRIPCIÓN MATEMÁTICA Y ANÁLISIS DE ESTABILIDAD DE PROCESOS FERMENTATIVOS

    Directory of Open Access Journals (Sweden)

    VÍCTOR MANUEL TREJOS

    2009-01-01

    Full Text Available El auge de los procesos fermentativos como fuente de etanol carburante conduce a plantear estudios teóricos para el entendimiento detallado del proceso. En el presente trabajo se evalúa la producción de etanol en un sistema continuo con células de levadura. Los modelos de crecimiento microbiano Monod y Haldane son analizados en un CSTR reactor (Continuous Stirred Tank Reactor. Se analiza la estabilidad del sistema, el comportamiento dinámico, la caracterización de puntos de equilibrio, planos de fase y puntos de bifurcación para cada uno de los dos modelos de crecimiento.

  15. Diseño de los procesos para industrializar la soya

    OpenAIRE

    Barrigas Romero, Cesar Orlando; Miranda, Luis

    2009-01-01

    El objetivo general es el diseño de los procesos y de las líneas de producción a escala semi industrial para la obtención de productos alimenticios a base de soya. Para ello, en la primera parte se describe a la soya como materia prima, en la fase experimental establecimos parámetros de proceso para estandarizar resultados con 1 kilo de soya como base a fin de obtener leche, queso y yogurt de soya con la parte líquida; y con la parte sólida un producto tipo granola y tortitas a base de la mez...

  16. Intestinal Cgi-58 deficiency reduces postprandial lipid absorption.

    Science.gov (United States)

    Xie, Ping; Guo, Feng; Ma, Yinyan; Zhu, Hongling; Wang, Freddy; Xue, Bingzhong; Shi, Hang; Yang, Jian; Yu, Liqing

    2014-01-01

    Comparative Gene Identification-58 (CGI-58), a lipid droplet (LD)-associated protein, promotes intracellular triglyceride (TG) hydrolysis in vitro. Mutations in human CGI-58 cause TG accumulation in numerous tissues including intestine. Enterocytes are thought not to store TG-rich LDs, but a fatty meal does induce temporary cytosolic accumulation of LDs. Accumulated LDs are eventually cleared out, implying existence of TG hydrolytic machinery in enterocytes. However, identities of proteins responsible for LD-TG hydrolysis remain unknown. Here we report that intestine-specific inactivation of CGI-58 in mice significantly reduces postprandial plasma TG concentrations and intestinal TG hydrolase activity, which is associated with a 4-fold increase in intestinal TG content and large cytosolic LD accumulation in absorptive enterocytes during the fasting state. Intestine-specific CGI-58 knockout mice also display mild yet significant decreases in intestinal fatty acid absorption and oxidation. Surprisingly, inactivation of CGI-58 in intestine significantly raises plasma and intestinal cholesterol, and reduces hepatic cholesterol, without altering intestinal cholesterol absorption and fecal neutral sterol excretion. In conclusion, intestinal CGI-58 is required for efficient postprandial lipoprotein-TG secretion and for maintaining hepatic and plasma lipid homeostasis. Our animal model will serve as a valuable tool to further define how intestinal fat metabolism influences the pathogenesis of metabolic disorders, such as obesity and type 2 diabetes.

  17. Farewell to Animal Testing: Innovations on Human Intestinal Microphysiological Systems

    Directory of Open Access Journals (Sweden)

    Tae Hyun Kang

    2016-06-01

    Full Text Available The human intestine is a dynamic organ where the complex host-microbe interactions that orchestrate intestinal homeostasis occur. Major contributing factors associated with intestinal health and diseases include metabolically-active gut microbiota, intestinal epithelium, immune components, and rhythmical bowel movement known as peristalsis. Human intestinal disease models have been developed; however, a considerable number of existing models often fail to reproducibly predict human intestinal pathophysiology in response to biological and chemical perturbations or clinical interventions. Intestinal organoid models have provided promising cytodifferentiation and regeneration, but the lack of luminal flow and physical bowel movements seriously hamper mimicking complex host-microbe crosstalk. Here, we discuss recent advances of human intestinal microphysiological systems, such as the biomimetic human “Gut-on-a-Chip” that can employ key intestinal components, such as villus epithelium, gut microbiota, and immune components under peristalsis-like motions and flow, to reconstitute the transmural 3D lumen-capillary tissue interface. By encompassing cutting-edge tools in microfluidics, tissue engineering, and clinical microbiology, gut-on-a-chip has been leveraged not only to recapitulate organ-level intestinal functions, but also emulate the pathophysiology of intestinal disorders, such as chronic inflammation. Finally, we provide potential perspectives of the next generation microphysiological systems as a personalized platform to validate the efficacy, safety, metabolism, and therapeutic responses of new drug compounds in the preclinical stage.

  18. Intestinal Cgi-58 deficiency reduces postprandial lipid absorption.

    Directory of Open Access Journals (Sweden)

    Ping Xie

    Full Text Available Comparative Gene Identification-58 (CGI-58, a lipid droplet (LD-associated protein, promotes intracellular triglyceride (TG hydrolysis in vitro. Mutations in human CGI-58 cause TG accumulation in numerous tissues including intestine. Enterocytes are thought not to store TG-rich LDs, but a fatty meal does induce temporary cytosolic accumulation of LDs. Accumulated LDs are eventually cleared out, implying existence of TG hydrolytic machinery in enterocytes. However, identities of proteins responsible for LD-TG hydrolysis remain unknown. Here we report that intestine-specific inactivation of CGI-58 in mice significantly reduces postprandial plasma TG concentrations and intestinal TG hydrolase activity, which is associated with a 4-fold increase in intestinal TG content and large cytosolic LD accumulation in absorptive enterocytes during the fasting state. Intestine-specific CGI-58 knockout mice also display mild yet significant decreases in intestinal fatty acid absorption and oxidation. Surprisingly, inactivation of CGI-58 in intestine significantly raises plasma and intestinal cholesterol, and reduces hepatic cholesterol, without altering intestinal cholesterol absorption and fecal neutral sterol excretion. In conclusion, intestinal CGI-58 is required for efficient postprandial lipoprotein-TG secretion and for maintaining hepatic and plasma lipid homeostasis. Our animal model will serve as a valuable tool to further define how intestinal fat metabolism influences the pathogenesis of metabolic disorders, such as obesity and type 2 diabetes.

  19. Surgical management of radiation injury to the small intestine

    Energy Technology Data Exchange (ETDEWEB)

    Swan, R.W.; Fowler, W.C. Jr., Boronow, R.C.

    1976-01-01

    Severe injury of the small intestine represents one of the most tragic complications of radiation of the pelvis and abdomen. Not uncommonly, patients die from the radiation or the treatment of its intestinal complications. More commonly, patients become intestinal cripples, secondary to chronic partial obstruction of the small intestine and malnutrition associated with the stagnant loop syndrome, as previously reported by one of us. Management results have been discouraging, usually because of a general lack of clinical recognition and understanding of radiation injury to the intestine. Medical management has not been satisfactory. It may provide temporary relief from symptoms, but not long-lasting. Surgical management, although frequently curative, has been associated with high death and morbidity rates. Many surgical procedures have been used in treating radiation injury to the small intestine. Generally, these fall into two categories: first, intestinal resection with primary anastomosis; and second, enteroenteric or enterocolic bypass. In the literature are reflected advocates for each method of surgical management.

  20. Intestinal mucus accumulation in a child with acutemyeloblastic leukemia

    Directory of Open Access Journals (Sweden)

    Namık Özbek

    2009-12-01

    Full Text Available Intestinal mucus accumulation is a very rare situation observed in some solid tumors, intestinal inflammation, mucosal hyperplasia, elevated intestinal pressure, and various other diseases. However, it has never been described in acute myeloblastic leukemia. The pathogenesis of intestinal mucus accumulation is still not clear. Here, we report a 14-year-old girl with acute myeloblastic leukemia and febrile neutropenia in addition to typhlitis. She was also immobilized due to joint contractures of the lower extremities and had intestinal mucus accumulation, which was, at first, misdiagnosed as intestinal parasitosis. We speculate that typhlitis, immobilization and decreased intestinal motility due to usage of antiemetic drugs might have been the potential etiologic factors in this case. However, its impact on prognosis of the primary disease is unknown.