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Sample records for intestinal masiva proceso

  1. MODIFICACIÓN AL PROCESO DE PRODUCCIÓN MASIVA DE LOS PARASITOIDES Catolaccus grandis Y Catolaccus hunteri

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    Marco Antonio Reyes-Rosas

    2010-01-01

    Full Text Available El presente estudio se realizó con el objetivo de modificar la tecnología de producción masiva de Catolaccus grandis y Catolaccus hunteri, himenópteros parasitoides de Anthonomus grandis el picudo del algodonero en Tamaulipas, México en el 2002. Se determinó la eficiencia del papel toalla para el secado de manos, en el sellamiento de cápsulas moldeadas en cera de hidrocarburos y poliolefina (LCHP, donde se confina al huésped, y evaluar la efectividad del gorgojo del garbanzo Callosobruchus maculatus como hospedante facticio para la cría de ambos parasitoides. Hubo producción masiva de C. grandis y C. hunteri utilizando C. maculatus como huésped y el papel toalla fue efectivo para sellar los orificios de las cápsulas moldeadas en LCHP. La producción masiva de C. grandis y C. hunteri mediante C. maculatus, contribuyó a incrementar la seguridad y facilidad del proceso, además de una significativa reducción de costos. El papel toalla en el sellado de los orificios de las cápsulas moldeadas en LCHP, redujo en un 50% por m2 los costos del proceso, sin afectar la eficiencia del parasitismo y emergencia de C. grandis.

  2. Las negociaciones en el proceso penal: del procedimiento inquisitivo a la prisionización masiva

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    Julio César Montañez Ruiz

    2013-12-01

    Full Text Available La presente investigación plantea la problemática de la prisionización masiva que generan las negociaciones en el sistema procesal penal de tendencia acusatoria, con marcada influencia norteamericana; aquí se sostiene que ese mecanismo, mediante el cual la Fiscalía busca la declaratoria masiva de culpabilidad de los imputados en plan de descongestionar el sistema represivo penal, tiene las caraterísticas más inquisitivas de un sistema de enjuiciamiento penal.

  3. Condiciones físicas y químicas del gas alrededor de estrellas jóvenes masivas

    OpenAIRE

    Tercero Rodríguez, Belén

    2012-01-01

    Las estrellas masivas nacen en los núcleos de las nubes moleculares y alcanzan la edad adulta embebidas en estas regiones. Este hecho supone un problema para la observación directa de la formación de estos objetos ya que densas regiones de gas y polvo los oscurecen. Por otro lado, los violentos fenómenos asociados a este proceso (vientos, flujos bipolares, discos de acreción y radiación estelar) transforman las propiedades físicas y químicas del gas que rodea a las estrellas masivas recién na...

  4. SISTEMA PARA LA ADMINISTRACIÓN DE MATERIALES EN PROYECTOS DE CONSTRUCCIÓN MASIVA DE VIVIENDA

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    José Antonio González Fajardo

    2002-07-01

    Full Text Available Se propone un sistema para administrar los recursos materiales que intervienen en la construcción masiva de unidades habitacionales o vivienda unifamiliar. Esta propuesta es en sí, un planteamiento global de todas las etapas, fases y procesos administrativos que se consideran importantes integrar para llevar a cabo con éxito la función referida; se considera la administración de los materiales
    desde el desarrollo del diseño del proyecto hasta su utilización dentro de los procesos constructivos, pasando a través de las etapas de planeación, programación y control de los mismos.Se estima haber alcanzado un alto nivel de detalle en cada una de las etapas que se definieron. Se aprovechan las características particulares de administración que se presentan en los proyectos de construcción masiva de vivienda, debido al carácter repetitivo de las unidades habitacionales.Para el desarrollo del sistema se tomaron en cuenta aspectos tales como la administración efectiva de proyectos y su impacto en la productividad de las empresas constructoras de este ramo, así como la situación actual, necesidades y opiniones de los ejecutivos de estas empresas.

  5. Ascitis fetal masiva idiopática aislada

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    Yolimar Navarro Briceño

    2016-08-01

    Full Text Available La ascitis fetal esta comúnmente asociada a malformaciones gastrointestinales y urinarias, anemia, infección y anomalías cromosómicas. La ascitis fetal masiva idiopática es rara. Se reporta un caso de una embarazada de 33 años referida a las 17 semanas después que se detectó ascitis en ausencia de anomalías estructurales. La evaluación cardiaca y las pruebas diagnósticas de infecciones virales fueron negativas. A las 28 semanas se detectó ascitis masiva sin otros signos de hidrops fetal. La velocidad sistólica pico de la arteria cerebral media fetal estaba elevada. El Doppler de la arteria umbilical, crecimiento fetal y volumen de líquido amniótico estaban normales. El ecocardiograma fetal estaba normal. Se realizó la amniocentesis con resultados normales del cariotipo. A pesar de la persistencia de la ascitis masiva durante el seguimiento, el crecimiento fetal y el volumen de líquido amniótico eran normales con valores elevados de la velocidad sistólica pico de la arteria cerebral media fetal. A las 33 semanas la paciente se realizó cesárea de emergencia por sufrimiento fetal agudo. Se obtuvo un recién nacido vivo femenino normal con valores normales de hemoglobina al nacer. El flujo vascular hepático, vesical y hepato-portal fueron normales. La ascitis se resolvió completamente al octavo día después del nacimiento y el recién nacido fue dado de alta a los 15 días.

  6. LA COMUNICACIÓN MASIVA Y EL COMPORTAMIENTO DEL CONSUMIDOR

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    Natalia Golovina

    2014-07-01

    Full Text Available En el presente escrito utilizando las técnicas de investigación documental se hace un análisis de la comunicación masiva en dos direcciones: como herramienta de poder de las empresas sobre los consumidores, causando los efectos cognitivos, afectivos y actitudinales, moldeando los motivos de compra y como el medio de ejercicio de poder de los consumidores sobre las empresas, obligándolas actuar con mayor ética y transparencia, a través de la posibilidad de hacer públicas sus opiniones y valoraciones tanto positivas como negativas sobre un determinado producto, imagen corporativa, posicionamiento de la marca, calidad de los mensajes publicitarios.

  7. Embolectomía en una embolia pulmonar aguda masiva

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    Manuel Carnero Alcázar

    2007-07-01

    Full Text Available Presentamos el caso de un varón de 57 años que, en el seno de un meningioma microcítico, padece una tromboembolia pulmonar masiva aguda con inestabilidad hemodinámica. Dado el riesgo de hemorragia por el tumor craneal, se contraindica la terapia fibrinolítica y se procede a practicar embolectomía pulmonar. Ésta se realiza bajo anestesia general, con canulación convencional y bajo hipotermia moderada. Se extrae émbolo en el tronco de la arteria pulmonar y con catéter de Fogarty se extraen émbolos en ramas lobares y segmentarias. Discutimos la asociación de enfermedad tromboembólica con determinadas neoplasias y el tratamiento de la tromboembolia pulmonar

  8. SECCIÓN TEMÁTICA - 5. LA EVACUACIÓN MASIVA // MASS EVACUATION

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    Alexis Lorenzo Ruiz

    2012-06-01

    Full Text Available Ante la inminente amenaza de un huracán, volcán, incendio o incluso ante un riesgo nuclear, el factor que más vidas salva es la evacuación oportuna. Esta medida no solo depende de la capacidad organizativa en el momento de la catástrofe, sino también de una adecuada reacción social. La respuesta social a una evacuación masiva está determinada principalmente por el nivel de confianza entre autoridades y sociedad civil. Alcanzar dichos niveles requiere de un ejercicio de gobierno que invierta tanto en factores tangibles (tales como políticas públicas, sistemas de aviso temprano y otros recursos, como en atributos intangibles (v.g., formación de Capital Social y capacitación ciudadana.Bajo esta premisa, la seguridad y rapidez con que se desarrollan las evacuaciones por la proximidad de un huracán en un país con escasos recursos económicos como Cuba, merece de un estudio que indague en los factores no tangibles que coadyuvan al éxito de este proceso. A partir de un extenso trabajo documental y mediante la aplicación de entrevistas individuales y grupales, este texto examina las movilizaciones ciudadanas cubanas producidas por el posible impacto de un evento hidrometeorológico extremo y el valor de la inversión en capital social y cognitivo en la construcción de relaciones de confianza en situaciones de riesgo.

  9. Impacto de los medios de comunicación masiva en una campaña antitabaco

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    Sansores Raúl H

    2002-01-01

    Full Text Available Objetivo. Determinar en México el impacto de los medios de comunicación masiva (MCM en el proceso de dejar de fumar. Material y métodos. Evaluamos, entre junio de 1998 y mayo de 1999, el efecto de una campaña en los MCM de México, así como el de estrategias alternas, comparando el promedio mensual de ventas de todos los productos auxiliares para dejar de fumar antes y después del lanzamiento de un Parche Nuevo de nicotina. Se usó t pareada o de Student para comparar las ventas. Resultados. Las ventas totales aumentaron de 24 206±4 558 a 55 604±8 993 (p<0.0001. Estimamos que 1 853 fumadores intentaron dejar de fumar y 96 lo consiguieron diariamente con un solo producto después de la promoción. Estrategias alternas para conseguir resultados similares indican que programas de una institución del sector público podrían conseguir que seis personas dejaran de fumar y 501 lo intentaran diariamente. Conclusiones. Los MCM tienen un efecto poderoso en el proceso para dejar de fumar y la inclusión de más instituciones del sector público podría igualar lo obtenido por el sector privado.

  10. Reprogramación celular de embriones de Anthurium andraeanum por fitohormonas para micropropagación masiva

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    Julieta Mireles-Ordaz

    2015-01-01

    Full Text Available El género Anthurium incluye alrededor de 800 especies, las cuales son originarias de diversos países tropicales y subtropicales de América. Numerosos cultivos de estas especies de Anthurium son crecidos y comercializados debido a su gran popularidad como plantas ornamentales alrededor de todo el mundo, de las cuales la más popular es Anthurium andreanum. La reproducción sexual de estas plantas en invernaderos es difícil y toma mucho tiempo, lo cual representa una desventaja para su producción masiva y comercialización. La micropropagación in vitro ha emergido como una opción para sobrellevar dicha desventaja, hasta la fecha se han logrado avances parcialmente exitosos en la micropropagación en especies de Anthurium usando varios tejidos como explantes iniciales, incluyendo hojas, pecíolo, espádice, espata, brote lateral, meristemo apical y embriones somáticos, estos últimos previamente inducidos a partir de tejido diferenciado. Sin embargo, hasta ahora no hay reportes del uso de embriones cigóticos como tejido madre para la propagación masiva de estas plantas. En el presente estudio reportamos la formación de callos organogénicos a partir de embriones cigóticos inmaduros crecidos en medio MS suplementado con la combinación de 2 mg/l de ácido 2,4-diclorofenoxiacético (2,4-D y 0.5 mg/l de 6-benzilamino-purina (BAP. Los resultados obtenidos demuestran que los embriones en proceso de desarrollo son altamente eficientes como explantes de origen para inducir la formación de tejido calloso de una manera rápida y fácil, dando en promedio 9 brotes por callo y logrando una taza de sobrevivencia de las plantas del 90% en la fase de aclimatación.

  11. Culturas fan y cultura masiva: prácticas e identidades juveniles de otakus y gamers

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    Federico Álvarez Gandolfi

    2015-01-01

    Full Text Available [es] El objetivo de este trabajo es dar cuenta de cómo, en torno de productos mediáticos y prácticas socioculturales comunes, los fans del anime o series animadas japonesas –autodenominados otakus– y los fans de los videojuegos japoneses –autodenominados gamers– elaboran un universo simbólico propio y compartido sobre el cual pueden construir identidades juveniles que son diferentes entre sí. El interés por las significaciones que producen estos fans surge del auge de la cultura masiva japonesa en la Argentina, evidenciado, por ejemplo, en la transmisión de distintos animes por las emisoras nacionales de televisión por aire Telefe y Canal 9, en ciclos organizados por la Facultad de Ciencias Sociales de la Universidad de Buenos Aires y en documentales del Canal Encuentro –gestionado por el Ministerio de Educación de la Nación Argentina–, así como en la promoción institucional de dichas series animadas y de los videojuegos en Tecnópolis –muestra nacional de arte, ciencia y tecnología–, la Feria Internacional del Libro de Buenos Aires y la Agenda Cultural del Gobierno de la Ciudad de Buenos Aires. Es así como, desde una perspectiva socioantropológica y comunicacional, cabe reflexionar sobre los usos y reapropiaciones que hacen los jóvenes fans de los objetos de la cultura de masas japonesa que viven en la Ciudad de Buenos Aires. Asimismo, hay que tener en cuenta que las distintas prácticas desarrolladas en torno del consumo de estos productos están encuadradas dentro de flujos globales que generan procesos interculturales de construcción de identidades, inscriptos a la vez en relaciones de poder intraculturales y procesos alternativos de producción cultural. [en] This work aims to give an account of how fans of anime or Japanese animated series –self-described otakus– and fans of Japanese video games –self-described gamers– create their own and shared symbolic universe around common media products and

  12. Impacto de los medios de comunicación masiva en una campaña antitabaco

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    Raúl H Sansores

    2002-01-01

    Full Text Available Objetivo. Determinar en México el impacto de los medios de comunicación masiva (MCM en el proceso de dejar de fumar. Material y métodos. Evaluamos, entre junio de 1998 y mayo de 1999, el efecto de una campaña en los MCM de México, así como el de estrategias alternas, comparando el promedio mensual de ventas de todos los productos auxiliares para dejar de fumar antes y después del lanzamiento de un Parche Nuevo de nicotina. Se usó t pareada o de Student para comparar las ventas. Resultados. Las ventas totales aumentaron de 24 206±4 558 a 55 604±8 993 (pAbstract Objective To assess the impact of the mass media (MM on smoking cessation process in Mexico. Material and Methods. Between June 1998 and May 1999, the effects of an anti-smoking mass media campaign and alternative strategies were evaluated, by comparing the monthly sales average of all smoking-cessation aid products before and after marketing a new nicotine patch. Student's t paired and unpaired t tests were used to compare sales. Results. Total sales increased from 24 206±4 558 to 55 604±8 993 (p<0.0001. It was estimated that 1 853 smokers tried to quit and 96 per day succeeded with a single product after the campaign. Alternative strategies to get similar results indicate that the programs of a single public sector institution could help 501 persons attempt quitting smoking and six to accomplish it per day. Conclusions. The mass media have a powerful effect on smoking cessation practices; the involvement of more public institutions may accomplish similar results as the private sector.

  13. El legado del Movimiento Moderno. Conjuntos de vivienda masiva en ciudades europeas del Oeste y del Este. No tan diferentes…

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    Javier Monclús

    2015-05-01

    Full Text Available El objetivo de este artículo es comparar y contrastar algunos conjuntos de vivienda modernos en ciudades europeas del Oeste (“capitalistas” y del Este (“socialistas”. Nuestro trabajo se centra en conjuntos de vivienda masiva construidos en el periodo de crecimiento urbano acelerado que tuvo lugar en Europa principalmente en las décadas de los años 60 y 70 del pasado siglo. El punto de partida más obvio es que las ciudades socialistas son diferentes de las europeas occidentales por la distinta naturaleza de sus políticas urbanas, el sistema de planificación económica socialista centralizada, la ausencia de un mercado del suelo libre, el impacto de la industrial­ización en el sector de la construcción, etc. Sin embargo, hay muchos conceptos en urbanismo, así como en los procesos urbanos, que fueron compartidos en ambos sistemas políticos e ideológicos. El artículo ofrece una perspectiva comparada de la naturaleza de esos conjuntos residenciales modernos construidos a ambos lados del Telón de Acero –Housing Es­tates en UK, Grands Ensembles en Francia, Großsiedlungen en Alemania, Polígonos en España o los grandes conjuntos residenciales socialistas en los países del Bloque del Este– con el fin de entender mejor si –y hasta qué punto– las formas urbanas de dichos conjuntos son el resultado de la cultura internacional del urbanismo moderno.

  14. Guía clínica para el manejo interdisciplinario del paciente con secuelas de pérdida masiva de peso durante la cirugía plástica reconstructiva

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    Alejandro Portes-Castro

    2016-03-01

    Full Text Available Antecedentes y Objetivos. La obesidad está considerada como una pandemia y México ocupa uno de los primeros lugares mundiales en número de casos en población adulta y el primero en el grupo infantil. Desde 2008 se pusieron en marcha Unidades de Cirugía Bariátrica para el manejo del paciente obeso, con lo cual se inició también la Reconstrucción postpérdida masiva de peso por los Servicios de Cirugía Plástica. Sin embargo, no existen protocolos descritos de manejo perioperatorio de este tipo de pacientes en nuestro país. El objetivo del presente trabajo es crear una guía clínica para el manejo interdisciplinario del paciente con secuelas de pérdida masiva de peso basada en los resultados obtenidos en un centro de reconstrucción postbariátrica. Material y Método. Creamos para ello un equipo de expertos de cada área involucrada y se estandarizó el manejo pre, trans y postoperatorio de todos los pacientes con secuelas de pérdida masiva de peso a fin de evaluar los resultados obtenidos. Resultados. Se realizaron 314 procedimientos reconstructivos en 144 pacientes postbariátricos. El 93% fueron de sexo femenino. La edad promedio fue de 37.2 años. Los procedimientos realizados fueron: abdominoplastia en un 39.17%; mastopexia en un 10.5%; torsoplastia en un 7.69%; braquioplastia en un 7.01%; cruroplastia en un 5.09%; y ritidoplastia en un 2.54%. El tiempo quirúrgico promedio fue de 221.2 minutos, con un sangrado transoperatorio medio de 275 ml. Las complicaciones presentadas alcanzaron el 4.77% y la mortalidad fue de 0%. Las recomendaciones emitidas por cada experto involucrado en el proceso de reconstrucción permitieron obtener resultados favorables en relación a la morbi-mortalidad, que fue equiparable e incluso inferior a la reportada en otras series. Conclusiones. Creemos que el seguimiento de una guía clínica basada en la estandarización del manejo de 314 procedimientos en una población con características similares

  15. Estrellas masivas

    OpenAIRE

    Najarro, Francisco

    2007-01-01

    Presentado en el IV Curso de Iniciación a la Investigación en Estructura de la Materia: Desde las partículas subatómicas hasta los compuestos moleculares (Instituto de Estructura de la Materia, CSIC, 28-30 de Marzo de 2007).

  16. Producción masiva de Romanomermis iyengari (Nematoda: Mermithidae y su aplicación en criaderos de anofelinos en Boa Vista (Roraima, Brasil

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    Alberto Santamarina Mijares

    2000-03-01

    Full Text Available Para desarrollar la producción masiva del nemátodo Romanomermis iyengari Welch, se llevó a cabo el diseño y montaje de una bioplanta en las instalaciones de la Universidad Federal del Estado de Roraima, Brasil, tras un convenio con la Secretaría de Salud del mencionado estado. El objetivo de este trabajo fue establecer el proceso básico de cría masiva del parásito para su posterior aplicación en criaderos de anofelinos. Se obtuvieron 68 cultivos por cada ciclo de siete días, con un total de 272 cultivos por mes. Antes de los tratamientos de campo se realizaron pruebas de laboratorio en las que se comprobó la gran susceptibilidad de las larvas de anofelinos a la infestación por R. iyengari, con tasas de parasitismo de 71 a 98%. Para evaluar la capacidad parasitaria de R. iyengari en condiciones de campo, se seleccionaron 12 criaderos naturales de anofelinos, con áreas que oscilaron entre 50 y 450 m², en los que se observó la presencia de larvas de mosquitos de las especies Anopheles albitarsis Lynch-Arribálzaga y Anopheles rondoni Neiva-Pinto, con densidades de 34 a 66 larvas/m². Para la dispersión del biolarvicida en los 12 criaderos se utilizó una bomba costal manual de fabricación nacional a una presión de dos atmósferas y se aplicó una dosis de 2 000 preparásitos/m². Siete días después de los tratamientos se observó una marcada reducción (85 a 97% de las poblaciones de anofelinos. Los resultados obtenidos demostraron la posibilidad de utilizar R. iyengari para controlar las poblaciones larvarias de ambas especies de anofelinos.

  17. Producción masiva de Romanomermis iyengari (Nematoda: Mermithidae y su aplicación en criaderos de anofelinos en Boa Vista (Roraima, Brasil

    Directory of Open Access Journals (Sweden)

    Santamarina Mijares Alberto

    2000-01-01

    Full Text Available Para desarrollar la producción masiva del nemátodo Romanomermis iyengari Welch, se llevó a cabo el diseño y montaje de una bioplanta en las instalaciones de la Universidad Federal del Estado de Roraima, Brasil, tras un convenio con la Secretaría de Salud del mencionado estado. El objetivo de este trabajo fue establecer el proceso básico de cría masiva del parásito para su posterior aplicación en criaderos de anofelinos. Se obtuvieron 68 cultivos por cada ciclo de siete días, con un total de 272 cultivos por mes. Antes de los tratamientos de campo se realizaron pruebas de laboratorio en las que se comprobó la gran susceptibilidad de las larvas de anofelinos a la infestación por R. iyengari, con tasas de parasitismo de 71 a 98%. Para evaluar la capacidad parasitaria de R. iyengari en condiciones de campo, se seleccionaron 12 criaderos naturales de anofelinos, con áreas que oscilaron entre 50 y 450 m², en los que se observó la presencia de larvas de mosquitos de las especies Anopheles albitarsis Lynch-Arribálzaga y Anopheles rondoni Neiva-Pinto, con densidades de 34 a 66 larvas/m². Para la dispersión del biolarvicida en los 12 criaderos se utilizó una bomba costal manual de fabricación nacional a una presión de dos atmósferas y se aplicó una dosis de 2 000 preparásitos/m². Siete días después de los tratamientos se observó una marcada reducción (85 a 97% de las poblaciones de anofelinos. Los resultados obtenidos demostraron la posibilidad de utilizar R. iyengari para controlar las poblaciones larvarias de ambas especies de anofelinos.

  18. MORTALIDAD DE TRANSFUSIÓN MASIVA TEMPRANA EN PACIENTES CON TRAUMA PENETRANTE EN EL HOSPITAL UNIVERSITARIO SAN JORGE DE PEREIRA

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    Juan Pablo Arismendy-Muñoz

    2011-01-01

    Full Text Available La violencia y la accidentalidad son causas frecuentes de trauma en Colombia. Diferentes alternativas sobre el correcto manejo del paciente traumatizado han sido elaboradas debido a la necesidad de mejorar los protocolos para modificar de manera favorable el pronóstico de los pacientes; uno de estos ha sido la implementación de hemotransfusión masiva temprana. Se realizó un estudio con el objetivo de Identificar el número de pacientes ingresados al Hospital Universitario San Jorge de Pereira con trauma penetrante a cuello, tórax, abdomen y extremidades que cumplieron criterios para hemotransfusión masiva temprana y determinar el porcentaje de los que fueron transfundidos durante los meses de Febrero y Marzo de 2010. A partir de esto se llevó a cabo un estudio descriptivo que incluyó 64 historias clínicas de pacientes con diagnostico de trauma penetrante en las zonas anatómicas ya descritas, ingresados al Hospital universitario San Jorge de Pereira empleando un instrumento que incluía los criterios para hemotransfusión temprana y algunas variables epidemiológicas. Los resultados reflejan que el 3% de los pacientes incluidos, tenían criterios para trasfusión masiva temprana, esta no fue empleada en su protocolo de reanimación y el 97% de los pacientes estudiados no cumplía criterios de transfusión. Para determinar la utilidad de la trasfusión masiva temprana en el Hospital Universitario San Jorge, se requiere la implementación de protocolos de reanimación en los cuales se incluya los criterios de trasfusión temprana, con la finalidad de poder evaluar sobrevida en investigaciones ulteriores.

  19. Readquisición de la tolerancia asociativa al etanol: el efecto de la extinción masiva

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    Consuelo San Martín

    2018-05-01

    Full Text Available El consumo repetido de ciertas drogas produce tolerancia, es decir, la disminución de sus efectos y la necesidad de obtener, por lo tanto, mayores dosis. Desde el paradigma del condicionamiento pavloviano, en la presente investigación dos experimentos examinaron el impacto del uso de cantidad masiva de ensayos de extinción en la readquisición de la tolerancia al etanol. En el experimento 1 se evaluó la adquisición, extinción y readquisición de la tolerancia al etanol en ratas tras 9 ensayos de extinción. En el experimento 2 se evaluó el efecto de 84 ensayos de extinción en la readquisición de la tolerancia. En ambos experimentos se midió la tolerancia al etanol mediante la respuesta atáxica de los sujetos en un plano inclinado. Los resultados del experimento 1 mostraron adquisición, extinción y readquisición de la tolerancia al etanol. Los resultados del experimento 2 mostraron que la extinción masiva logró atenuar la readquisición. En conjunto, los resultados de este estudio sugieren que la exposición masiva a estímulos asociados con el consumo de etanol pueden ser efectivos para reducir la tolerancia y la recaída.

  20. Regiones de formación de estrellas masivas en las Nubes de Magallanes

    Science.gov (United States)

    Barbá, R.; Maíz Apellániz, J.; Rubio, M.; Walborn, N.

    Las Nubes de Magallanes son un laboratorio formidable para el estudio de regiones de formación estelar. A diferencia de lo que sucede en el plano galáctico, ambas galaxias contienen poco polvo que nos afecte la visión directa de dichas regiones. Por otra parte, la menor metalicidad de las Nubes, nos permiten hacer un estudio comparativo de la formación estelar en ambientes de baja metalicidad. El presente trabajo da una revisión de los progresos notables que hemos alcanzado en el conocimiento del contenido estelar de algunas regiones de formación de estrellas masivas en ambas Nubes, en base a la utilización de imágenes del Telescopio Espacial Hubble, Gemini Sur, y Very Large Telescope, entre otros. En especial, nos concentramos en 30 Doradus y N11 en la Nube Mayor, y en NGC 346 en la Nube Menor. Nuevas imágenes de N11 obtenidas en los últimos meses con la Advanced Camera for Surveys del Hubble (óptico), y con Flamingos en Gemini Sur (infrarrojo), nos han permitido descubrir un nuevo `jet' con origen en una fuente infrarroja sumergida en un pilar polvoriento similar al objeto Herbig-Haro de M20 en nuestra galaxia. Este `jet' (junto a otros tres que hemos descubierto en 30 Doradus), es el cuarto ejemplo confirmado de `jet' asociado a una protoestrella fuera de nuestra galaxia. Además, presentamos el descubrimiento del primer objeto estelar joven masivo de la Nube Menor confirmado espectroscópicamente.

  1. Intestinal Cancer

    Science.gov (United States)

    ... connects your stomach to your large intestine. Intestinal cancer is rare, but eating a high-fat diet ... increase your risk. Possible signs of small intestine cancer include Abdominal pain Weight loss for no reason ...

  2. Micropropagación masiva de Stevia rebaudiana Bertoni en sistemas de inmersión temporal

    OpenAIRE

    Alvarenga Venutolo, Silvana

    2015-01-01

    Stevia rebaudiana Bertoni, familia Asteraceae, es conocida como “yerba dulce” por poseer un edulcorante natural. Sus propiedades provienen de la presencia de glicósidos diterpenos denominados esteviósidos y rebaudiósidos en las hojas. El porcentaje de germinación de las semillas de S. rebaudiana es muy bajo y las plantas producidas son heterogéneas, por lo que no es conveniente para la propagación masiva en campo. El cultivo en sistemas de inmersión temporal, es una herramienta eficaz para la...

  3. La Aproximación de las Estrategias de la UE y EEUU en la Lucha contra la Proliferación de Armas de Destrucción Masiva

    Directory of Open Access Journals (Sweden)

    Milagros Álvarez

    2012-10-01

    Full Text Available El cambio en el seno de la Administración estadounidense tras las elecciones de 2008 y la consiguiente adopción de nuevos documentos estratégicos en la lucha contra la proliferación de armas de destrucción masiva suscitan nuevamente el interés de su comparación con los planteamientos defendidos por la UE, al objeto de identificar la posible emergencia de nuevos márgenes de coincidencia entre ambos actores internacionales y, con ello, el impulso a nuevos compromisos en el régimen de no proliferación. La comparación revela tres tendencias fundamentales: estancamiento en el proceso de mejora y perfeccionamiento de la regulación prevista para las armas químicas y biológicas, desarrollo selectivo del régimen de no proliferación nuclear, y consolidación de la cooperación informal y ad hoc como instrumento contra la proliferación de ADM.

  4. ABSENTISMO Y ROTACIÓN EN LA CONSTRUCCIÓN MASIVA DE VIVIENDA. EFECTO EN LA PRODUCTIVIDAD

    Directory of Open Access Journals (Sweden)

    Carlos Enrique Arcudia Abad

    2003-09-01

    Full Text Available

    El trabajo está enfocado a dos aspectos importantes y poco estudiados, y que predominan en la mano de obra de albañilería en la construcción masiva de vivienda: el absentismo y la rotación. En esta investigación se tuvo como objetivo: desarrollar una metodología para medir dichos fenómenos, realizar esta y, posteriormente, efectuar un análisis de correlación entre estos y la productividad con el fin de determinar una posible relación. El estudio se encaminó a dos niveles de organización de la mano de obra de albañilería: en la brigada y en la cuadrilla, según se tratase de todo el grupo que labora en una o más unidades de vivienda o del que desarrolla una actividad de construcción específica en las mismas. La investigación abarca dos proyectos de construcción masiva de vivienda. Los resultados obtenidos fueron cotejados con los reportes de estudios realizados en otros contextos, los cuales se basaban en índices de absentismo de la brigada en grandes proyectos de construcción.

  5. La Psicología Social Comunitaria en procesos de reubicación masiva: una experiencia de la Gran Misión Vivienda Venezuela

    Directory of Open Access Journals (Sweden)

    Luis Fernando Giuliani

    2017-11-01

    Full Text Available La Psicología Social Comunitaria cuenta con un sostenido desarrollo  teórico y metodológico que representa un gran potencial de aplicabilidad en la solución de diversos problemas sociales y en el desarrollo de las comunidades.  Por su parte, el contexto venezolano actual, donde casi todas las políticas públicas implican un alto nivel de protagonismo de la organización y la participación comunitaria, es sumamente propicio para que las ciencias sociales en general y, la Psicología Social Comunitaria en particular, integren sus aportes. En función de estos planteamientos, en el presente trabajo presentamos una experiencia realizada en el marco de la Gran Misión Vivienda Venezuela, política pública impulsada por el estado venezolano que asume una perspectiva comunitaria y participativa. La experiencia en cuestión se desarrolló entre diciembre del 2013 y diciembre del 2014 y estuvo adscripta al Gobierno del Distrito Capital, en Caracas, Venezuela. Tuvo como eje central el desarrollo e implementación de un Enfoque Comunitario Integral destinado a servir de orientación al trabajo que realizaron los equipos con las poblaciones ubicadas en los nuevos urbanismos construidos por el estado. El diseño e implementación del Enfoque, integró buena parte de las propuestas teórico -  conceptuales de la Psicología Comunitaria.   Palabras clave: vivienda, comunidad, organización, participación, políticas públicas.

  6. Amebiasis intestinal Intestinal amebiasis

    Directory of Open Access Journals (Sweden)

    JULIO CÉSAR GÓMEZ

    2007-03-01

    Full Text Available Entamoeba histolytica es el patógeno intestinal más frecuente en nuestro medio -después de Giardia lamblia-, una de las principales causas de diarrea en menores de cinco años y la cuarta causa de muerte en el mundo debida a infección por protozoarios. Posee mecanismos patogénicos complejos que le permiten invadir la mucosa intestinal y causar colitis amebiana. El examen microscópico es el método más usado para su identificación pero la existencia de dos especies morfológicamente iguales, una patógena ( E. histolytica y una no patógena ( Entamoeba dispar, ha llevado al desarrollo de otros métodos de diagnóstico. El acceso al agua potable y los servicios sanitarios adecuados, un tratamiento médico oportuno y el desarrollo de una vacuna, son los ejes para disminuir la incidencia y mortalidad de esta entidad.Entamoeba histolytica is the most frequent intestinal pathogen seen in our country, after Giardia lamblia, being one of the main causes of diarrhea in children younger than five years of age, and the fourth leading cause of death due to infection for protozoa in the world. It possesses complex pathogenic mechanisms that allow it to invade the intestinal mucosa, causing amoebic colitis. Microscopy is the most used method for its identification, but the existence of two species morphologically identical, the pathogen one ( E. histolytica, and the non pathogen one ( E. dispar, have taken to the development of other methods of diagnosis. The access to drinkable water and appropriate sanitary services, an opportune medical treatment, and the development of a vaccine are the axes to diminish the incidence and mortality of this entity.

  7. Intestinal Lymphangiectasia

    Science.gov (United States)

    ... Overview of Crohn Disease Additional Content Medical News Intestinal Lymphangiectasia (Idiopathic Hypoproteinemia) By Atenodoro R. Ruiz, Jr., MD, ... Overview of Malabsorption Bacterial Overgrowth Syndrome Celiac Disease Intestinal ... Intolerance Short Bowel Syndrome Tropical Sprue Whipple ...

  8. Intestinal Obstruction

    Science.gov (United States)

    ... Colostomy ) is required to relieve an obstruction. Understanding Colostomy In a colostomy, the large intestine (colon) is cut. The part ... 1 What Causes Intestinal Strangulation? Figure 2 Understanding Colostomy Gastrointestinal Emergencies Overview of Gastrointestinal Emergencies Abdominal Abscesses ...

  9. Mortandad masiva de mesodesma mactroides (bivalvia: mactracea) en el partido de la Costa, Buenos Aires, Argentina, en septiembre 2004

    OpenAIRE

    Thompson, Gustavo; Bock, Mariana Federica Sánchez de

    2007-01-01

    La almeja amarilla Mesodesma mactroides ha sido diezmada por vários eventos de mortandad masiva a lo largo de su distribución en Brasil, Uruguay y Argentina. Este estudio evalúa y compara la concentración de As, Cd, Cr, Cu, Ni, Pb y Zn, em los tejidos de las almejas colectadas durante un evento de mortandad en Septiembre 2004 y un año después. La cuantificación de los metales se realizó por digestión ácida y posterior determinación por espectrometría. Los valores de Cd, Cu y Pb (11 ± 2, 42 ± ...

  10. Intestinal Surgery.

    Science.gov (United States)

    Desrochers, André; Anderson, David E

    2016-11-01

    A wide variety of disorders affecting the intestinal tract in cattle may require surgery. Among those disorders the more common are: intestinal volvulus, jejunal hemorrhage syndrome and more recently the duodenal sigmoid flexure volvulus. Although general principles of intestinal surgery can be applied, cattle has anatomical and behavior particularities that must be known before invading the abdomen. This article focuses on surgical techniques used to optimize outcomes and discusses specific disorders of small intestine. Diagnoses and surgical techniques presented can be applied in field conditions. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. Mortalidad de transfusión masiva temprana en pacientes con trauma penetrante en el hospital universitario San Jorge de Pereira

    Directory of Open Access Journals (Sweden)

    Juan Pablo Arismendy-Muñoz

    2012-09-01

    Full Text Available La violencia y la accidentalidad son causas frecuentes de trauma en Colombia. Diferentes alternativas sobre el correcto manejo del paciente traumatizado han sido elaboradas debido a la necesidad de mejorar los protocolos para modificar de manera favorable el pronóstico de los pacientes; uno de estos ha sido la implementación de hemotransfusión masiva temprana. Se realizó un estudio con el objetivo de Identificar el número de pacientes ingresados al Hospital Universitario San Jorge de Pereira con trauma penetrante a cuello, tórax, abdomen y extremidades que cumplieron criterios para  hemotransfusión masiva temprana y  determinar el porcentaje de los que fueron transfundidos durante los meses de Febrero y Marzo de 2010. A partir de esto se llevó a cabo un estudio descriptivo que incluyó 64 historias clínicas de pacientes con diagnostico de trauma penetrante en las zonas anatómicas ya descritas, ingresados al Hospital universitario San Jorge de Pereira empleando un instrumento que incluía los criterios para hemotransfusión temprana y algunas variables epidemiológicas. Los resultados reflejan que el 3% de los pacientes incluidos, tenían criterios para trasfusión masiva temprana, esta no fue empleada en su protocolo de reanimación y el 97% de los pacientes estudiados no cumplía criterios de transfusión. Para determinar la utilidad de la trasfusión masiva temprana en el Hospital Universitario San Jorge, se requiere la implementación de protocolos de reanimación en los cuales se incluya los criterios de trasfusión temprana,  con la finalidad de poder evaluar sobrevida en investigaciones  ulteriores

  12. Intestine transplantation

    Directory of Open Access Journals (Sweden)

    Tadeja Pintar

    2011-02-01

    Conclusion: Intestine transplantation is reserved for patients with irreversible intestinal failure due to short gut syndrome requiring total paranteral nutrition with no possibility of discontinuation and loss of venous access for patient maintenance. In these patients complications of underlying disease and long-term total parenteral nutrition are present.

  13. La finalidad del proceso

    Directory of Open Access Journals (Sweden)

    Iván Alfonso Cordero Gutiérrez

    2011-07-01

    Full Text Available Resumen:El tipo de Estado que Colombia asumió desde 1991 (Estado Social de Derecho, implica que el cumplimiento de los fines estatales se comparten con la población, generando de esta forma grados de responsabilidad respecto a las cargas asumidas por ellos y el Estado para la materialización de los objetivos planteados. La satisfacción de las necesidades básicas de la población como unode los fines esenciales del Estado Social de Derecho, no escapa a este esquema, lo que determina la colaboración armónica no sólo entre las entidades y organismos del Estado sino de este, complementado con la población. Una de las necesidades básicas de la población, se refiere a la posibilidad de resolver sus conflictos haciendo uso de los mecanismos que para tal efecto tiene a su disposición, utilizando las formas de Auto tutela, Autocomposición, híbridas y de Heterocomposiciòn, que el Estado autoriza,de acuerdo a los lineamientos propios de cada mecanismo, respecto a las materias que componen los derechos sustanciales que se debaten en la relación conflictiva. Dentro de estos mecanismos de solución de conflictos, la heterocomposiciòn presenta uno llamado el proceso jurisdiccional, en donde un tercero investido de poderes específicos ejerce la jurisdicción y toma la decisión respecto al conflicto, después del agotamiento de etapas sucesivas y preclusivas que garantizan la efectiva participación, ejercicio y defensa de los derechos fundamentales y sustanciales de las partes, generando una mayor garantía de legalidad respecto a la decisión generada por ese tercero investido de plena Jurisdicción (el Juez. Por ser el proceso jurisdiccional el mecanismo más idóneo por su garantismo reglado y tecnificado, debe ser protegido, fortalecido y preferente respecto a los denominados equivalentesjurisdiccionales pues con estos el Estado pretende desplazar la competencia al momento de la resolución de los conflictos, generando un

  14. Intestinal leiomyoma

    Science.gov (United States)

    ... most often found when a person has an upper gastrointestinal (GI) endoscopy or colonoscopy for another reason. Rarely, these tumors can cause bleeding, blockage or rupture of the intestines If this ...

  15. Small Intestine Disorders

    Science.gov (United States)

    ... disease Crohn's disease Infections Intestinal cancer Intestinal obstruction Irritable bowel syndrome Ulcers, such as peptic ulcer Treatment of disorders of the small intestine depends on the cause.

  16. El proceso constituyente venezolano

    Directory of Open Access Journals (Sweden)

    Ricardo COMBELLAS

    2009-11-01

    Full Text Available RESUMEN: La Asamblea Nacional Constituyente permitirá redefinir el marco institucional de la república venezolana. Este proceso constituyente iniciado en 1989 aborda una etapa definitiva debido al apoyo mayoritario de los venezolanos y a que ha sido asumido como bandera por el hoy presidente Hugo Chávez.El paradigma constitucional ha tenido tropiezos originados por el populismo, el clientelismo, la corrupción, la falta de un trabajo legislativo oportuno, la falta de garantías a los derechos fundamentales, el deterioro del poder judicial y la falta de una participación política abierta.Para llevar a cabo una asamblea nacional constituyente es fundamental la participación amplia que lleve a un consenso constructivo. Es decir, se tratará de iniciar el 25 de abril una constituyente originaria que implica que su capacidad decisoria no esté sujeta a ningún poder establecido, ya que su origen es la expresión política de la soberanía popular que va a modificar el ordenamiento jurídico existente.ABSTRACT: The National Assembly Constituency will permit the redefinition of the institutional framework of the Venezuelan Republic. This fundamental process started in 1989 outlines a definitive stage due to the major support of the Venezuela people, and has been assumed as the platform of present president Hugo Chávez.The constitutional paradigm has flaws that originate from the following: populism, clientelism, corruption, the lack of timely legislative work, the lack of guarantees to basic rights, the deterioration of judicial power, and the lack of open political participation.For the National Assembly Constituency to work, extensive participation is fundamental to bring forth constructive consensus. As its origins now is the political expression of popular sovereignty that modifies the existing judicial order, it wil try to iniciate on the 25th of April a new constituency that implies that its capacity for decision making is not subject to

  17. Las técnicas de secuenciación masiva en el estudio de la diversidad biológica.

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    Unai López de Heredia

    2016-01-01

    Full Text Available Las técnicas de análisis genómico que se basan en la secuenciación masiva han supuesto una revolución en la última década no sólo en biomedicina o agronomía, sino también en el estudio de la diversidad biológica. Las plataformas de secuenciación de segunda y tercera generación que vienen a complementar a la tradicional secuenciación por el método Sanger, permiten analizar un gran número de individuos obteniendo una profundidad de secuenciación significativa de sus genomas o transcriptomas. Así, aunque todavía de manera incipiente, se vienen realizando estudios sobre la flora y fauna silvestre a escala poblacional, con especial énfasis en la determinación de patrones adaptativos frente a los cambios ambientales. En la presente revisión se describe la situación actual de las plataformas de secuenciación masiva, señalando sus ventajas y limitaciones para el análisis en organismos no modelo, para a continuación detallar las bases de dos de las técnicas más populares que se benefician de la secuenciación masiva (RAD-seq y RNA-seq y señalar algunos ejemplos de su uso para el estudio de la diversidad biológica.

  18. Un Protocolo Conversacional de una Entrevista de Corte Policiaco a un Detenido, Difundida en los Medios de Comunicación Masiva

    OpenAIRE

    Vázquez Laslop María Eugenia

    2017-01-01

    El 30 de agosto de 2010 la Policía Federal mexicana detuvo a uno de los capos del narcotráfico más buscados del momento, Édgar Valdez Villarreal, “La Barbie”. Durante los primeros días de septiembre la Secretaría de Seguridad Pública difundió en los medios de comunicación masiva fragmentos de una entrevista al detenido realizada el 31 de agosto, que seguía un formato en apariencia oficial e institucional. El objetivo de este artículo es describir la entrevista a modo de protocolo en términos ...

  19. Privacidad en internet: los derechos fundamentales de privacidad e intimidad en internet y su regulación jurídica. La vigilancia masiva

    OpenAIRE

    González Porras, Andrés José

    2016-01-01

    La investigación que se presenta, trata de un estudio jurídico de la vigilancia masiva y la afectación de los derechos de intimidad, secreto a las comunicaciones y la protección de las personas frente al tratamiento de sus datos personales. Ciertamente, los avances de las tecnologías, en los últimos años, han transformado a los seres humanos en muchos sentidos y han permitido un progreso sin precedentes. La sociedad contemporánea depende en muchos aspectos de las facilidades ofrecidas por...

  20. Nuevo enfoque para el estudio de la productividad en la construcción masiva de vivienda

    Directory of Open Access Journals (Sweden)

    Carlos Enrique Arcudia Abad

    2002-01-01

    Full Text Available La investigación de la productividad de la mano de obra puede ser un medio que coadyuve al incremento del nivel de vida y de las condiciones de trabajo de los obreros. En este trabajo se aplica el Modelo de los factores para el estudio de la productividad del trabajo en la industria de la construcción, en cuatro proyectos de vivienda masiva del tipo de interés social. Se realizaron mediciones de los trabajos efectuados en cuatro proyectos por sendas cuadrilla en el concepto muro a base de bloques de concreto. Los datos obtenidos se analizaron con apoyo en la teoría para la evaluación de la productividad de la mano de obra, que se fundamenta en el concepto de la línea base de cada proyecto, la cual está relacionada básicamente con la complejidad del diseño. Esta relación se establece por medio de un modelo de regresión. Se definen dos índices con el objeto de medir la calidad en la ejecución de los trabajos: el índice de días de bajo ritmo (ISR y el índice de administración de proyecto (IAP. El primero mide el porcentaje de días de trabajo anormal o de baja productividad, y el segundo remueve la influencia del diseño en la medida de la productividad para mostrar el efecto de la organización y administración de la obra. Se desarrolla una metodología para la comparación de los cuatro proyectos, usando las curvas de probabilidad acumulada de IBR e lAR encontrándose que un proyecto dado puede presentar mejor desempeño en su ejecución, a pesar de tener cuantitativamente menor productividad, considerando la complejidad del trabajo por ejecutar.

  1. Proyecto de reforma del Proceso Penal

    Directory of Open Access Journals (Sweden)

    Beatriz Scapusio

    2014-04-01

    Full Text Available El Anteproyecto de Código de Proceso PenalExpositora: Beatriz ScapusioLa Imputabilidad Aportes dogmáticos para un tema clave de la responsablidad penalExpositor: Dardo Preza RestucciaEstructuras procesales en el proceso de conocimiento y en el proceso de ejecuciónExpositora: Raquel Landeira

  2. INTESTINAL OBSTRUCTION

    Science.gov (United States)

    Whipple, G. H.; Stone, H. B.; Bernheim, B. M.

    1913-01-01

    Closed duodenal loops may be made in dogs by ligatures placed just below the pancreatic duct and just beyond the duodenojejunal junction, together with a posterior gastro-enterostomy. These closed duodenal loop dogs die with symptoms like those of patients suffering from volvulus or high intestinal obstruction. This duodenal loop may simulate closely a volvulus in which there has been no vascular disturbance. Dogs with closed duodenal loops which have been washed out carefully survive a little longer on the average than animals with unwashed loops. The duration of life in the first instance is one to three days, with an average of about forty-eight hours. The dogs usually lose considerable fluid by vomiting and diarrhea. A weak pulse, low blood pressure and temperature are usually conspicuous in the last stages. Autopsy shows more or less splanchnic congestion which may be most marked in the mucosa of the upper small intestine. The peritoneum is usually clear and the closed loop may be distended with thin fluid, or collapsed, and contain only a small amount of pasty brown material. The mucosa of the loop may show ulceration and even perforation, but in the majority of cases it is intact and exhibits only a moderate congestion. Simple intestinal obstruction added to a closed duodenal loop does not modify the result in any manner, but it may hasten the fatal outcome. The liver plays no essential role as a protective agent against this poison, for a dog with an Eck fistula may live three days with a closed loop. A normal dog reacts to intraportal injection and to intravenous injection of the toxic substance in an identical manner. Drainage of this loop under certain conditions may not interfere with the general health over a period of weeks or months. Excision of the part of the duodenum included in this loop causes no disturbance. The material from the closed duodenal loops contains no bile, pancreatic juice, gastric juice, or split products from the food. It can be

  3. El proceso emprendedor en Chile

    OpenAIRE

    José Miguel Benavente

    2004-01-01

    Este estudio analiza los factores que afectan en forma positiva y negativa el proceso de creación de emprendimientos dinámicos en Chile. Se basa en una encuesta a 200 empresas jóvenes, la cual es parte de una muestra de casi 2000 empresas de América Latina. El presente estudio se enfoca básicamente en el segmento de nuevos emprendimientos existentes en Chile.

  4. Efecto de la suplementación con una dosis masiva de vitamina A en niños de 6 a 36 meses de edad

    Directory of Open Access Journals (Sweden)

    Robles-Sardin Alma E.

    1998-01-01

    Full Text Available Objetivo. Evaluar el impacto de la suplementación con una dosis masiva de vitamina A en el estado nutricio de dicha vitamina y del hierro, en niños de zonas urbanas marginadas de Hermosillo, Sonora, México. Material y métodos. Se seleccionaron 60 niños (6-36 meses, a los que se les administró una dosis de 100 000 UI (6-12 meses y 200 000 UI (12-36 meses de vitamina A en el Día Nacional de Salud de la Secretaría de Salud (junio de 1994. Se midieron niveles séricos de retinol, carotenoides, hierro, transferrina y ferritina, en tres fases: basal, a las dos semanas y después de tres meses. Resultados. En la primera fase, la mediana de retinol fue 0.7µmol/l; en la segunda aumentó a 0.97µmol/l (p 0.05. Un 6.3% de los niños presentó deficiencia severa de vitamina A al inicio, y no se encontró ningún caso en las fases posteriores a la suplementación. En la fase basal, 42% de los casos presentaron deficiencia moderada y la mayoría fue normal en las siguientes fases. No hubo diferencias en los niveles de hierro y transferrina (p > 0.05, pero sí en ferritina (p < 0.001, lo que indica un mejoramiento en las reservas de hierro a los tres meses. Conclusiones. Las campañas de distribución de dosis masivas pueden tener un impacto importante en el estado nutricio de vitamina A y hierro.

  5. Optimizaión de un protocolo para el cultivo in vitro y la micropropagación masiva del llantén (Plantago major

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    Giovanni Garro M.

    2009-01-01

    Full Text Available Llantén (P. major posee propiedades medicinales antiinflamatorias y cicatrizantes que han sido aprovechadas en muchas latitudes desde épocas remotas. Los estudios del cultivo in vitro de esta especie son escasos, a pesar de las ventajas que este tipo de técnicas presenta en especies de uso medicinal. En este trabajo se logró desarrollar un protocolo para el establecimiento y la reproducción masiva in vitro del llantén. Se estableció un protocolo de desinfección de semillas y se obtuvo plántulas germinadas in vitro que se utilizaron como fuente de explantes para la fase de micropropagación masiva. Se evaluó el cultivo de ápices en medios de cultivo con sales y vitaminas de M & S (1962 al 100% y al 50%, suplementados con los siguientes reguladores de crecimiento: 1,2mg/l de ANA (Ácido naftalenacético, 0,6 mg/l y 0,4 mg/l de BAP (Bencil amino purina y 1mg/l de TDZ (Tidiazurón en diferentes combinaciones. Los mejores resultados en la inducción de brotes fueron obtenidos en 14,9 brotes promedio por explante en el medio con las sales y vitaminas M & S (1962 reducidas al 50% de su concentración y sin reguladores de crecimiento. Con este tratamiento, un total de 150 vitroplantas provenientes de distintos tratamientos han sido llevadas a condiciones de invernadero con un 100% de sobrevivencia.

  6. Intestinal myiasis

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    U S Udgaonkar

    2012-01-01

    Full Text Available Purpose: Intestinal myiasis is a condition when the fly larvae inhabit the gastrointestinal tract and are passed out in faeces. This type of infestation results when eggs or larvae of the fly, deposited on food are inadvertently taken by man. They survive the unfavourable conditions within the gastrointestinal tract and produce disturbances, which may vary from mild to severe. The condition is not uncommon and is often misdiagnosed as pinworm infestation. Correct diagnosis by the clinical microbiologist is important to avoid unnecessary treatment. Materials and Methods: We had 7 cases of intestinal myiasis. In 2 cases the larvae were reared to adult fly in modified meat and sand medium (developed by Udgaonkar. This medium is simple and can be easily prepared in the laboratory. Results: Of the 7 larvae, 5 were Sarcophaga haemorrhoidalis, 1 Megaselia species and 1 was identified as Muscina stabulans. Conclusions: S. haemorrhoidalis was the commonest maggot involved. A high index of suspicion is required for clinical diagnosis when the patient complains of passing wriggling worms in faeces for a long period without any response to antihelminthics. The reason for long duration of illness and recurrence of infestation is baffling. The nearest to cure was colonic wash. We feel prevention is of utmost importance, which is to avoid eating food articles with easy access to flies.

  7. Intestinal myiasis.

    Science.gov (United States)

    Udgaonkar, U S; Dharamsi, R; Kulkarni, S A; Shah, S R; Patil, S S; Bhosale, A L; Gadgil, S A; Mohite, R S

    2012-01-01

    Intestinal myiasis is a condition when the fly larvae inhabit the gastrointestinal tract and are passed out in faeces. This type of infestation results when eggs or larvae of the fly, deposited on food are inadvertently taken by man. They survive the unfavourable conditions within the gastrointestinal tract and produce disturbances, which may vary from mild to severe. The condition is not uncommon and is often misdiagnosed as pinworm infestation. Correct diagnosis by the clinical microbiologist is important to avoid unnecessary treatment. We had 7 cases of intestinal myiasis. In 2 cases the larvae were reared to adult fly in modified meat and sand medium (developed by Udgaonkar). This medium is simple and can be easily prepared in the laboratory. Of the 7 larvae, 5 were Sarcophaga haemorrhoidalis, 1 Megaselia species and 1 was identified as Muscina stabulans. S. haemorrhoidalis was the commonest maggot involved. A high index of suspicion is required for clinical diagnosis when the patient complains of passing wriggling worms in faeces for a long period without any response to antihelminthics. The reason for long duration of illness and recurrence of infestation is baffling. The nearest to cure was colonic wash. We feel prevention is of utmost importance, which is to avoid eating food articles with easy access to flies.

  8. Debido proceso, sistemas y reforma del proceso penal

    Directory of Open Access Journals (Sweden)

    Teresa Armenta Deu

    2015-03-01

    Full Text Available Este artículo se propone examinar los modelos de procesos penales de los movimientos de reforma que se establecieron en las últimas décadas del siglo XX, en los países iberoamericanos. Para ello, primero se enfatiza las características históricas de cada sistema, poniendo de relieve la importancia de no confundir el acusatorio con el adversarial, rechazando la coincidencia entre los sistemas actuales y mixto inquisitivo histórico. Apoya la importancia de la igualdad de armas y e del contradictoria en la búsqueda de un equilibrio entre los modelos de procedimiento.

  9. La perestroika, un proceso direccional

    Directory of Open Access Journals (Sweden)

    Edgardo Erazo Obando

    1990-04-01

    Full Text Available El artículo presenta una visión diferente de las implicaciones, efectos y resultados  de un proceso histórico como lo es la Perestroika. Este término acuñado como propio en nuestra cultura occidental, ha representado para la Unión  Soviética y sus “países asociados” la transformación de los principios filosóficos, económicos, políticos y organizacionales. Es importante reconocer que el “cambio” cuando se realiza  en forma amplia produce en cualquier institución u organización el “fenómeno de resistencia”, para la Perestroika, este hecho  no ha sido extraño y, se ha constituido en uno de los grandes problemas a vencer, toda vez, que de él depende el éxito o fracaso del proceso de reestructuración. De todas formas, la mayor incidencia la recibirá el sector empresarial, que deberá transformarse a pasos de gigante para lograr niveles de eficiencia y productividad que garanticen el desarrollo de la política socio – económica del nuevo plan.  Ojalá esta transformación implique para la administración de una nueva teoría direccional

  10. [Adult intestinal malrotation associated with intestinal volvulus].

    Science.gov (United States)

    Hernando-Almudí, Ernesto; Cerdán-Pascual, Rafael; Vallejo-Bernad, Cristina; Martín-Cuartero, Joaquín; Sánchez-Rubio, María; Casamayor-Franco, Carmen

    Intestinal malrotation is a congenital anomaly of the intestinal rotation and fixation, and usually occurs in the neonatal age. Description of a clinical case associated with acute occlusive symptoms. A case of intestinal malrotation is presented in a previously asymptomatic woman of 46 years old with an intestinal obstruction, with radiology and surgical findings showing an absence of intestinal rotation. Intestinal malrotation in adults is often asymptomatic, and is diagnosed as a casual finding during a radiological examination performed for other reasons. Infrequently, it can be diagnosed in adults, associated with an acute abdomen. Copyright © 2016 Academia Mexicana de Cirugía A.C. Publicado por Masson Doyma México S.A. All rights reserved.

  11. Intestinal Ostomy.

    Science.gov (United States)

    Ambe, Peter C; Kurz, Nadja Rebecca; Nitschke, Claudia; Odeh, Siad F; Möslein, Gabriela; Zirngibl, Hubert

    2018-03-16

    About 100 000 ostomy carriers are estimated to live in Germany today. The creation of an ostomy represents a major life event that can be associated with impaired quality of life. Optimal ostomy creation and proper ostomy care are crucially important determinants of the success of treatment and of the patients' quality of life. This article is based on pertinent publications retrieved by a selective search in PubMed, GoogleScholar, and Scopus, and on the authors' experience. Intestinal stomata can be created using either the small or the large bowel. More than 75% of all stomata are placed as part of the treatment of colorectal cancer. The incidence of stoma-related complications is reported to be 10-70%. Skin irritation, erosion, and ulceration are the most common early complications, with a combined incidence of 25-34%, while stoma prolapse is the most common late complication, with an incidence of 8-75%. Most early complications can be managed conservatively, while most late complications require surgical revision. In 19% of cases, an ostomy that was initially planned to be temporary becomes permanent. Inappropriate stoma location and inadequate ostomy care are the most common causes of early complications. Both surgical and patient-related factors influence late complications. Every step from the planning of a stoma to its postoperative care should be discussed with the patient in detail. Preoperative marking is essential for an optimal stoma site. Optimal patient management with the involvement of an ostomy nurse increases ostomy acceptance, reduces ostomy-related complications, and improves the quality of life of ostomy carriers.

  12. Intestinal tract diseases

    International Nuclear Information System (INIS)

    Rozenshtraukh, L.S.

    1985-01-01

    Roentgenoanatomy and physiology of the small intestine are described. Indications for radiological examinations and their possibilities in the diagnosis of the small intestine diseases are considered.Congenital anomalies and failures in the small intestine development, clinical indications and diagnosis methods for the detection of different aetiology enteritis are described. Characteristics of primary malabsorption due to congenital or acquired inferiority of the small intestine, is provided. Radiological picture of intestinal allergies is described. Clinical, morphological, radiological pictures of Crohn's disease are considered in detail. Special attention is paid to the frequency of primary and secondary tuberculosis of intestinal tract. The description of clinical indications and frequency of benign and malignant tumours of the small intestine, methods for their diagnosis are given. Radiological pictures of parasitogenic and rare diseases of the small intestine are presented. Changes in the small intestine as a result of its reaction to pathological processes, developing in other organs and systems of the organism, are described

  13. Optimización y automatización del proceso de compra para tiendas de consumo masivo a través de tecnología móvil y jee

    OpenAIRE

    Iñiguez Jarrín, Carlos Efraín

    2013-01-01

    Es un sistema de análisis de adquisición de bienes o servicios, a través de la web, calidad, precio, lugar, promociones y más en cualquier parte del mundo. El proyecto de Gestión de Compras Masivas se compone de dos aplicaciones; una para ser instalada y ejecutada en teléfonos móviles con plataforma Android y otra basada en web, desarrollada en plataforma JEE que es en sí la administración de la solución completa. La solución está diseñada para optimizar y automatizar el proceso de comp...

  14. LOS NIVELES DE MICROCONTAMINANTES ORGÁNICOS EXPLICAN UNA MUERTE MASIVA DE PECES EN EL RÍO ATOYAC, PUEBLA, MÉXICO

    Directory of Open Access Journals (Sweden)

    Amado E. Navarro

    2017-01-01

    Full Text Available Se reportó una muerte masiva de peces en el río Atoyac, presumiendo como causa el vertido de algún contaminante químico muy tóxico. El análisis de muestras de agua, sedimentos y tejidos, mostró una baja concentración de oxígeno disuelto y elevadas de amonio y de nitritos en el río el día del incidente, probables causas directas de la muerte de los peces. Por cromatografía de gases/espectrometría de masas, no se detectaron contaminantes persistentes pero sí, concentraciones elevadas de microcontaminantes orgánicos antrópicos, lo cual indica un vertido de residuos municipales al cauce de la corriente, causa indirecta de la muerte de los peces. Las concentraciones de coprostanol y epicoprostanol indican la presencia de heces de mamíferos, incluidas las de rumiantes, en el vertido. Los resultados obtenidos muestran la utilidad de determinar las concentraciones de los microcontaminantes orgánicos para esclarecer las causas de estos incidentes.

  15. ENFERMEDAD PSICOGÉNICA MASIVA DESPUÉS DE UNA CAMPAÑA DE VACUNACIÓN EPISODIOS ANTERIORES Y APROXIMACIÓN AL CASO COLOMBIANO

    Directory of Open Access Journals (Sweden)

    Alfredo Jácome Roca

    2014-10-01

    Full Text Available Al revisar en la base de datos PubMed los términos “enfermedad psicogénica masiva” y “vacunación”, solo aparecen ocho referencias. Curiosamente todos esos casos asociados con vacunación masiva –con excepción de un brote acaecido en España con hepatitis B - se presentaron en países orientales como China y Taiwan y el virus de influenza AH1N1, Irán después de toxoide tetánico, Vietnam con vacuna oral de cólera y Jordania con un toxoide diftérico-tetánico. No se refiere la literatura a casos asociados a vacunación contra el VPH. Si se solo se investiga el término “enfermedad psicogénica masiva”, las referencias ascienden a 78, ya que estos fenómenos han venido siendo informados desde 1374, refiriéndose a bailes compulsivamente contagiosos o a risa contagiosa, y se asocian con situaciones reales o hasta cierto punto imaginarias que pueden crear pánico en una comunidad.

  16. Ángeles Sin Fronteras , A.C. y el proceso de deportación a Mexicali, Baja California

    Directory of Open Access Journals (Sweden)

    Tatiana E. Lara San Luis

    2014-01-01

    Full Text Available Las políticas migratorias estadounidenses que buscan a toda costa repatriar mexicanos desde los Estados Unidos no son nuevas. Contrario a lo que se pueda pensar, la deportación y repatriación hacia la frontera norte de México forman parte de un largo proceso histórico. En el caso de la frontera noroeste del país, la necesidad de dar solución a las deportaciones masivas, iniciadas luego de la década de 1990, o más bien, mejorar las condiciones en que se realizan, ha impulsado la formación de asociaciones —civiles o religiosas— destinadas a proporcionar apoyo a los connacionales recién llegados. Un ejemplo claro de ellas es la conformada por migrantes deportados y ciudadanos de la ciudad de Mexicali, Ángeles Sin Fronteras, quienes a partir de la puesta en marcha del Hotel del Migrante, proporcionan alojamiento y comida de manera gratuita a varones deportados a dicha población. Asimismo, permiten la participación activa de la comu � nidad a partir de donaciones y la interacción de los migrantes en la que se vuelve su nueva ciudad, generando mecanismos de sobrevivencia para quienes han quedado a la intemperie.

  17. Intestinal pseudo-obstruction

    Science.gov (United States)

    ... Staying in bed for long periods of time (bedridden). Taking drugs that slow intestinal movements. These include ... be tried: Colonoscopy may be used to remove air from the large intestine. Fluids can be given ...

  18. Procesos de cambio en organizaciones productivas

    OpenAIRE

    Laverde Carmona, Myriam Patricia

    2008-01-01

    El presente estudio de carácter exploratorio, basado en procesos de cambios en organizaciones productivas, involucra cuatro organizaciones altamente significativas de diferentes sectores de Medellín -- Estas Organizaciones han incursionado en procesos de cambio, donde los trabajadores jugaron un papel importante como partícipes del proceso y de las prácticas realizadas, destacando la participación e integración de los diferentes niveles jerárquicos de la organización en la planeación de activ...

  19. Periodo reproductivo y talla de madurez masiva del camarón de roca Sicyonia penicillata (Decapoda: Sicyoniidae en Bahía Kino, Sonora, México

    Directory of Open Access Journals (Sweden)

    J. López-Martínez

    1999-06-01

    Full Text Available Se estudia el periodo reproductivo del camarón de roca Sicyonia penicillata en el área de Bahía Kino, Sonora, de enero a diciembre de 1996 mediante muestreos quincenales efectuados a bordo de embarcaciones de la flota camaronera comercial y un crucero de investigación durante julio. La actividad reproductiva de la especie inicia a partir de los 25 mm de longitud abdominal, pero la talla de madurez sexual masiva de la especie se ubicó en 55 mm de longitud abdominal. Se encontraron organismos maduros todo el año, pero el patrón de reclutamiento indica que existe un periodo reproductivo masivo de agosto a enero; un segundo periodo, menos intenso ocurre en marzo y abril. Estos resultados son coincidentes para los meses en los que se cuenta con datos de madurez gonádica. Se postula la idea de un posible patrón de migración de juveniles hacia áreas someras de Bahía Kino.The reproductive pattern of the rock shrimp (Sicyonia penicillata was studied from January through December (1996 by sampling from boats twice a month (commercial shrimp fleet and one research cruise. Reproductive activity begins at 25 mm of tail length, but massive maturity or critical size is 55 mm of tail length. Mature organisms were found year round, but recruitment pattern analysis indicates that massive reproduction is from August through January; a second, less intense reproductive peak, occurs in March-April. Results are coincident with the gonadical maturity analysis. A migration pattern of juveniles towards shallow areas of Bahía Kino is suggested.

  20. Difusión masiva de información en los modelos de gestión de redes: aplicación a los servicios de alta disponibilidad sobre Internet

    OpenAIRE

    Marcos Jorquera, Diego

    2010-01-01

    En la presente tesis se propone un modelo de gestión de redes que incorpora en su definición la gestión y difusión masiva de la información sobre redes no propietarias como Internet. Este modelo viene a solucionar uno de los problemas más comunes para cualquier aplicación, tanto de gestión como de usuario, proporcionando un mecanismo sencillo, intuitivo y normalizado para transferir grandes volúmenes de información, con independencia de su localización o los protocolos de acceso. Algunas de l...

  1. Gastric and intestinal surgery.

    Science.gov (United States)

    Fossum, Theresa W; Hedlund, Cheryl S

    2003-09-01

    Gastric surgery is commonly performed to remove foreign bodies and correct gastric dilatation-volvulus and is less commonly performed to treat gastric ulceration or erosion, neoplasia, and benign gastric outflow obstruction. Intestinal surgery, although commonly performed by veterinarians, should never be considered routine. The most common procedures of the small intestinal tract performed in dogs and cats include enterotomy and resection/anastomosis. Surgery of the large intestine is indicated for lesions causing obstruction, perforations, colonic inertia, or chronic inflammation.

  2. Intestinal lymphangiectasia in children

    Science.gov (United States)

    Isa, Hasan M.; Al-Arayedh, Ghadeer G.; Mohamed, Afaf M.

    2016-01-01

    Intestinal lymphangiectasia (IL) is a rare disease characterized by dilatation of intestinal lymphatics. It can be classified as primary or secondary according to the underlying etiology. The clinical presentations of IL are pitting edema, chylous ascites, pleural effusion, acute appendicitis, diarrhea, lymphocytopenia, malabsorption, and intestinal obstruction. The diagnosis is made by intestinal endoscopy and biopsies. Dietary modification is the mainstay in the management of IL with a variable response. Here we report 2 patients with IL in Bahrain who showed positive response to dietary modification. PMID:26837404

  3. Intestinal parasites and tuberculosis

    Directory of Open Access Journals (Sweden)

    Anuar Alonso Cedeño-Burbano

    2017-10-01

    Conclusions: The available evidence was insufficient to affirm that intestinal parasites predispose to developing tuberculous. The studies carried out so far have found statistically insignificant results.

  4. Primary intestinal lymphangiectasia.

    Science.gov (United States)

    Suresh, N; Ganesh, R; Sankar, Janani; Sathiyasekaran, Malathi

    2009-10-01

    Primary intestinal lymphangiectasia (PIL) is a rare disease of intestinal lymphatics presenting with hypoproteinemia, bilateral lower limb edema, ascites, and protein losing enteropathy. We report a series of 4 children from Chennai, India presenting with anasarca, recurrent diarrhea, hypoproteinemia and confirmatory features of PIL on endoscopy and histopathology.

  5. Congenital intestinal lymphangiectasia

    Directory of Open Access Journals (Sweden)

    Popović Dušan Đ.

    2011-01-01

    Full Text Available Background. Congenital intestinal lymphangiectasia is a disease which leads to protein losing enteropathy. Tortous, dilated lymphatic vessels in the intestinal wall and mesenterium are typical features of the disease. Clinical manifestations include malabsorption, diarrhea, steatorrhea, edema and effusions. Specific diet and medication are required for disease control. Case report. A 19-year old male patient was hospitalized due to diarrhea, abdominal swelling, weariness and fatigue. Physical examination revealed growth impairment, ascites, and lymphedema of the right hand and forearm. Laboratory assessment indicated iron deficiency anaemia, lymphopenia, malabsorption, inflammatory syndrome, and urinary infection. Enteroscopy and video capsule endoscopy demonstrated dilated lymphatic vessels in the small intestine. The diagnosis was confirmed by intestinal biopsy. The patient was put on high-protein diet containing medium-chain fatty acids, somatotropin and suportive therapy. Conclusion. Congenital intestinal lymphangiectasia is a rare disease, usually diagnosed in childhood. Early recognition of the disease and adequate treatment can prevent development of various complications.

  6. [Congenital intestinal lymphangiectasia].

    Science.gov (United States)

    Popović, Dugan D j; Spuran, Milan; Alempijević, Tamara; Krstić, Miodrag; Djuranović, Srdjan; Kovacević, Nada; Damnjanović, Svetozar; Micev, Marjan

    2011-03-01

    Congenital intestinal lymphangiectasia is a disease which leads to protein losing enteropathy. Tortuous, dilated lymphatic vessels in the intestinal wall and mesenterium are typical features of the disease. Clinical manifestations include malabsorption, diarrhea, steatorrhea, edema and effusions. Specific diet and medication are required for disease control. A 19-year old male patient was hospitalized due to diarrhea, abdominal swelling, weariness and fatigue. Physical examination revealed growth impairment, ascites, and lymphedema of the right hand and forearm. Laboratory assessment indicated iron deficiency anaemia, lymphopenia, malabsorption, inflammatory syndrome, and urinary infection. Enteroscopy and video capsule endoscopy demonstrated dilated lymphatic vessels in the small intestine. The diagnosis was confirmed by intestinal biopsy. The patient was put on high-protein diet containing medium-chain fatty acids, somatotropin and supportive therapy. Congenital intestinal lymphangiectasia is a rare disease, usually diagnosed in childhood. Early recognition of the disease and adequate treatment can prevent development of various complications.

  7. Intestinal failure in childhood

    African Journals Online (AJOL)

    Insulin influences intestinal structure and absorptive function.36 The favourable effect of .... lipid emulsions, micronutrients provison and cyclic infusion.3 The guidelines on PN .... Classification, epidemiology and aetiology. Best Pract Res Clin ...

  8. Intestinal Permeability: The Basics

    Directory of Open Access Journals (Sweden)

    Ingvar Bjarnason

    1995-01-01

    Full Text Available The authors review some of the more fundamental principles underlying the noninvasive assessment of intestinal permeability in humans, the choice of test markers and their analyses, and the practical aspects of test dose composition and how these can be changed to allow the specific assessment of regional permeability changes and other intestinal functions. The implications of increased intestinal permeability in the pathogenesis of human disease is discussed in relation to findings in patients with Crohn’s disease. A common feature of increased intestinal permeability is the development of a low grade enteropathy, and while quantitatively similar changes may be found in Crohn’s disease these seem to predict relapse of disease. Moreover, factors associated with relapse of Crohn’s disease have in common an action to increase intestinal permeability. While increased intestinal permeability does not seem to be important in the etiology of Crohn’s disease it may be a central mechanism in the clinical relapse of disease.

  9. IDENTIFICACIÓN DE PROCESOS DE NEGOCIO

    Directory of Open Access Journals (Sweden)

    Anaisa Hernández González

    2005-06-01

    Full Text Available

    Para poder identificar correctamente cuáles son los requerimientos de un proyecto, es necesario conocer las características del negocio en el que se inserta. En el proceso de desarrollo del software la modelación del negocio adquiere mayor importancia por el impacto que tiene la utilización de las nuevas tecnologías. Este trabajo describe algunas reglas que ayudan a identificar procesos de negocio. El punto de partida es la propuesta de RUP y se incluyen recomendaciones y ejemplos derivados de su aplicación en diferentes entornos.

  10. Modernización del proceso administrativo

    Directory of Open Access Journals (Sweden)

    Carlos Martínez Fajardo

    1993-01-01

    Full Text Available En el presente artículo se pretende cuestionar la idea de que la Teoría Administrativa contempla un proceso administrativo rígido y obsoleto, imposible de aplicar en la práctica de la gerencia. Por el contrario, se sostiene y se demuestra que la teoría ha continuado estudiando y desarrollando el problema de las funciones de la gerencia moderna del año 2000.

  11. Intestinal lymphangiectasia in adults.

    Science.gov (United States)

    Freeman, Hugh James; Nimmo, Michael

    2011-02-15

    Intestinal lymphangiectasia in the adult may be characterized as a disorder with dilated intestinal lacteals causing loss of lymph into the lumen of the small intestine and resultant hypoproteinemia, hypogammaglobulinemia, hypoalbuminemia and reduced number of circulating lymphocytes or lymphopenia. Most often, intestinal lymphangiectasia has been recorded in children, often in neonates, usually with other congenital abnormalities but initial definition in adults including the elderly has become increasingly more common. Shared clinical features with the pediatric population such as bilateral lower limb edema, sometimes with lymphedema, pleural effusion and chylous ascites may occur but these reflect the severe end of the clinical spectrum. In some, diarrhea occurs with steatorrhea along with increased fecal loss of protein, reflected in increased fecal alpha-1-antitrypsin levels, while others may present with iron deficiency anemia, sometimes associated with occult small intestinal bleeding. Most lymphangiectasia in adults detected in recent years, however, appears to have few or no clinical features of malabsorption. Diagnosis remains dependent on endoscopic changes confirmed by small bowel biopsy showing histological evidence of intestinal lymphangiectasia. In some, video capsule endoscopy and enteroscopy have revealed more extensive changes along the length of the small intestine. A critical diagnostic element in adults with lymphangiectasia is the exclusion of entities (e.g. malignancies including lymphoma) that might lead to obstruction of the lymphatic system and "secondary" changes in the small bowel biopsy. In addition, occult infectious (e.g. Whipple's disease from Tropheryma whipplei) or inflammatory disorders (e.g. Crohn's disease) may also present with profound changes in intestinal permeability and protein-losing enteropathy that also require exclusion. Conversely, rare B-cell type lymphomas have also been described even decades following initial

  12. LOS PROCESOS DE ÚNICA INSTANCIA EN EL CÓDIGO GENERAL DEL PROCESO: LA GARANTÍA CONSTITUCIONAL DEL DEBIDO PROCESO Y LA DOBLE INSTANCIA

    OpenAIRE

    Jiménez Ramírez, Milton César; Yáñez Meza, Diego Armando

    2017-01-01

    En el presente artículo se evalúa la figura de la única instancia en la ley 1564/2012 o Código General del Proceso, con la finalidad de determinar si estos procesos son una infracción a la garantía constitucional del debido proceso y la doble instancia. Esta ley en sus artículos 17, 19 y 21, estableció la competencia de los jueces civiles municipales, civiles de circuito y de familia en procesos de única instancia, disposiciones que pueden constituirse como una infracción a la garantía proces...

  13. El papel de la densidad y la proporción sexual de adultos en la fecundidad de Diatraea saccharalis (Lepidoptera: Crambidae en jaulas de cría masiva

    Directory of Open Access Journals (Sweden)

    Pilar MEDINA PEREYRA

    2016-01-01

    Full Text Available La cría de insectos para control biológico aumentativo requiere conocer los factores que afectan la fecundidad para optimizar la producción masiva. En ge - neral, las prácticas empleadas se basan en los resultados de experiencias exitosas. Sin embargo, en muchos casos la verificación de esas prácticas en condiciones dis - tintas a las de su origen carece de soporte cuantitativo publicado y suele pasar por alto la variación derivada del manejo de los operarios (condición estándar. El ob - jetivo de este trabajo es evaluar la fecundidad del barrenador de la caña de azúcar Diatraea saccharalis Fabricius, en función del número de adultos y de la proporción sexual (número de hembras / número de adultos en jaulas de cría, en condiciones de producción estándar. En 25 jaulas se registraron número y sexo de las mariposas y número de huevos obtenido. Los resultados mostraron que la fecundidad óptima se obtiene con valores intermedios de densidad y con proporción sexual sesgada a machos. Se sugiere que el control conjunto de densidad y proporción sexual incre - menta la eficiencia en las posturas de huevos. El presente trabajo es el primero en cuantificar ambos factores en condiciones de cría masiva y revela que las prácticas comúnmente extendidas necesitan de estudios de mayor profundidad.

  14. Diagnosis of intestinal and extra intestinal amoebiasis

    International Nuclear Information System (INIS)

    Lopez, Myriam Consuelo; Quiroz, Damian Arnoldo; Pinilla, Analida Elizabeth

    2007-01-01

    The objective is to carry out a review of the national and international literature as of the XXth century in order to update the advances for the diagnosis of complex odd Entamoeba histolytic / Entamoeba dispar and that of intestinal and extra intestinal amoebiasis that may be of use to the scientific community. As well as to unify the diagnostic criteria of this parasitosis known as a public health problem, and as a consequence of that, optimize the quality of population care. Data source: there was a systematic search for the scientific literature Publisher in Spanish and English since 1960 until today, this selection started on the first semester of 2006 until 2007, in the development of the line on intestinal and extra-intestinal amoebiasis of the Medical School of the National University of Colombia. A retrospective search process was carried out, systematically reviewing the most relevant articles as well as the products of this research line. In deciding how to make this article, there was a continuous search in different data bases such as Medline, SciELO and other bases in the library of the National University of Colombia, as well as other classical books related to the subject. For that purpose the terms amoebiasis, odd Entamoeba histolytic, Entamoeba, diagnosis, epidemiology, dysentery, amoebic liver abscess, were used. Studies selection: titles and abstracts were reviewed to select the original publications and the most representative ones related to this article's subject. Data extraction: the articles were classified according to the subject, the chronology and the authors according to the scientific contribution to solve the problem. Synthesis of the data: in the fi rst instance, a chronological critical analysis was carried out to order and synthesize the progress made in the diagnosis until confirmation of the experts' agreements in the field of amoebiasis was obtained throughout the world. Conclusion: this article summarizes what has taken place

  15. Small intestine diverticuli

    International Nuclear Information System (INIS)

    Pomakov, P.; Risov, A.

    1991-01-01

    The routine method of contrast matter passage applied to 850 patients with different gastrointestinal diseases proved inefficient to detect any small-intestinal diverticuli. The following modiffications of the method have been tested in order to improve the diagnostic possibilities of the X-ray: study at short intervals, assisted passage, enteroclysm, pharmacodynamic impact, retrograde filling of the ileum by irrigoscopy. Twelve diverticuli of the small-intestinal loops were identified: 5 Meckel's diverticuli, 2 solitary of which one of the therminal ileum, 2 double diverticuli and 1 multiple diverticulosis of the jejunum. The results show that the short interval X-ray examination of the small intestines is the method of choice for identifying local changes in them. The solitary diverticuli are not casuistic scarcity, its occurrence is about 0.5% at purposeful X-ray investigation. The assisted passage method is proposed as a method of choice for detection of the Meckel's diverticulum. 5 figs., 3 tabs. 18 refs

  16. Chronic intestinal pseudoobstruction syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Yeon, Kyung Mo; Seo, Jeong Kee; Lee, Yong Seok [Seoul National University Children' s Hospital, Seoul (Korea, Republic of)

    1992-03-15

    Chronic intestinal pseudoobstruction syndrome is a rare clinical condition in which impaired intestinal peristalsis causes recurrent symptoms of bowel obstruction in the absence of a mechanical occlusion. This syndrome may involve variable segments of small or large bowel, and may be associated with urinary bladder retention. This study included 6 children(3 boys and 3 girls) of chronic intestinal obstruction. Four were symptomatic at birth and two were of the ages of one month and one year. All had abdominal distension and deflection difficulty. Five had urinary bladder distension. Despite parenteral nutrition and surgical intervention(ileostomy or colostomy), bowel obstruction persisted and four patients expired from sepses within one year. All had gaseous distension of small and large bowel on abdominal films. In small bowel series, consistent findings were variable degree of dilatation, decreased peristalsis(prolonged transit time) and microcolon or microrectum. This disease entity must be differentiated from congenital megacolon, ileal atresia and megacystis syndrome.

  17. Small Intestinal Infections.

    Science.gov (United States)

    Munot, Khushboo; Kotler, Donald P

    2016-06-01

    Small intestinal infections are extremely common worldwide. They may be bacterial, viral, or parasitic in etiology. Most are foodborne or waterborne, with specific etiologies differing by region and with diverse pathophysiologies. Very young, very old, and immune-deficient individuals are the most vulnerable to morbidity or mortality from small intestinal infections. There have been significant advances in diagnostic sophistication with the development and early application of molecular diagnostic assays, though these tests have not become mainstream. The lack of rapid diagnoses combined with the self-limited nature of small intestinal infections has hampered the development of specific and effective treatments other than oral rehydration. Antibiotics are not indicated in the absence of an etiologic diagnosis, and not at all in the case of some infections.

  18. Small intestine aspirate and culture

    Science.gov (United States)

    ... ency/article/003731.htm Small intestine aspirate and culture To use the sharing features on this page, please enable JavaScript. Small intestine aspirate and culture is a lab test to check for infection ...

  19. Reflexiones sobre el proceso salud-enfermedad

    OpenAIRE

    Velosa A., Lyla Piedad

    2010-01-01

    Desde que el individuo, las familias, las comunidades comenzaron a distinguir entre lo sano y lo enfermo, se inició un proceso de búsqueda de explicación, si se quiere de definición de los dos fenómenos. Desde entonces el hombre ha hecho enormes aportes en el plano del conocimiento de la naturaleza, de la sociedad y del pensamiento; descubriendo leyes, haciendo generalizaciones, que han revolucionado el desarrollo de sus costumbres y visión del mundo.

  20. Debido proceso o la novela del deterioro

    OpenAIRE

    Torres Gutiérrez, Carlos Luis

    2014-01-01

    La última obra de Jaime Alejandro Rodríguez 1, titulada Debido proceso, es definitivamente una novela urbana. Al terminar su lectura nos damos cuenota de que, al igual que la ciudad, el libro constituye un cruce de discursos, demiradas y de imágenes. Leerlo es enfrentarse a una ciudad translúcida donde se cruzanlo público y lo privado, lo real y lo imaginario, la pintura y la escritura, lo simpley lo profundo, la conciencia y la emotividad, el amor y la cursilería, la fatalidad y ladecisión, ...

  1. Intestinal inflammatory myofibroblastic tumour

    African Journals Online (AJOL)

    abdominal X-ray of patients 1, 3 and 4 demonstrated dilated small bowel loops with fluid levels in keeping with intestinal ... myxoid/vascular pattern characterised by a variable admixture of capillary-calibre blood vessels, .... in the present study had a past history of abdominal trauma or surgery. Ancillary histopathological ...

  2. Human Intestinal Spirochaetosis

    NARCIS (Netherlands)

    Westerman, L.J.

    2013-01-01

    Human intestinal spirochaetosis is a condition of the colon that is characterized by the presence of spirochaetes attached to the mucosal cells of the colon. These spirochaetes belong to the family Brachyspiraceae and two species are known to occur in humans: Brachyspira aalborgi and Brachyspira

  3. Intestinal health in carnivores

    NARCIS (Netherlands)

    Hagen-Plantinga, Esther A.; Hendriks, W.H.

    2015-01-01

    The knowledge on the influence of gastro-intestinal (GI) microbiota on the health status of humans and animals is rapidly expanding. A balanced microbiome may provide multiple benefits to the host, like triggering and stimulation of the immune system, acting as a barrier against possible pathogenic

  4. Intestinal Complications of IBD

    Science.gov (United States)

    ... localized pocket of pus caused by infection from bacteria. More common in Crohn’s than in colitis, an abscess may form in the intestinal wall—sometimes causing it to bulge out. Visible abscesses, such as those around the anus, look like boils and treatment often involves lancing. Symptoms of ...

  5. Intestinal volvulus in cetaceans.

    Science.gov (United States)

    Begeman, L; St Leger, J A; Blyde, D J; Jauniaux, T P; Lair, S; Lovewell, G; Raverty, S; Seibel, H; Siebert, U; Staggs, S L; Martelli, P; Keesler, R I

    2013-07-01

    Intestinal volvulus was recognized as the cause of death in 18 cetaceans, including 8 species of toothed whales (suborder Odontoceti). Cases originated from 11 institutions from around the world and included both captive (n = 9) and free-ranging (n = 9) animals. When the clinical history was available (n = 9), animals consistently demonstrated acute dullness 1 to 5 days prior to death. In 3 of these animals (33%), there was a history of chronic gastrointestinal illness. The pathological findings were similar to those described in other animal species and humans, and consisted of intestinal volvulus and a well-demarcated segment of distended, congested, and edematous intestine with gas and bloody fluid contents. Associated lesions included congested and edematous mesentery and mesenteric lymph nodes, and often serofibrinous or hemorrhagic abdominal effusion. The volvulus involved the cranial part of the intestines in 85% (11 of 13). Potential predisposing causes were recognized in most cases (13 of 18, 72%) but were variable. Further studies investigating predisposing factors are necessary to help prevent occurrence and enhance early clinical diagnosis and management of the condition.

  6. Small intestinal motility

    NARCIS (Netherlands)

    Smout, André J. P. M.

    2004-01-01

    PURPOSE OF REVIEW: In the past year, many studies were published in which new and relevant information on small intestinal motility in humans and laboratory animals was obtained. RECENT FINDINGS: Although the reported findings are heterogeneous, some themes appear to be particularly interesting and

  7. [Intrauterine intestinal volvulus].

    Science.gov (United States)

    Gawrych, Elzbieta; Chojnacka, Hanna; Wegrzynowski, Jerzy; Rajewska, Justyna

    2009-07-01

    Intrauterine intestinal volvulus is an extremely rare case of acute congenital intestinal obstruction. The diagnosis is usually possible in the third trimester of a pregnancy. Fetal midgut volvulus is most likely to be recognized by observing a typical clockwise whirlpool sign during color Doppler investigation. Multiple dilated intestinal loops with fluid levels are usually visible during the antenatal ultrasound as well. Physical and radiographic findings in the newborn indicate intestinal obstruction and an emergency surgery is required. The authors describe intrauterine volvulus in 3 female newborns in which surgical treatment was individualized. The decision about primary or delayed anastomosis after resection of the gangrenous part of the small bowel was made at the time of the surgery and depended on the general condition of the newborn, as well as presence or absence of meconium peritonitis. Double loop jejunostomy was performed in case of two newborns, followed by a delayed end-to-end anastomosis. In case of the third newborn, good blood supply of the small intestine after untwisting and 0.25% lignocaine injections into mesentery led to the assumption that the torsion was not complete and ischemia was reversible. In the two cases of incomplete rotation the cecum was sutured to the left abdominal wall to prevent further twisting. The postoperative course was uneventful and oral alimentation caused no problems. Physical development of all these children has been normal (current age: 1-2 years) and the parents have not observed any disorders or problems regarding passage of food through the alimentary canal. Prompt antenatal diagnosis of this surgical emergency and adequate choice of intervention may greatly reduce mortality due to intrauterine volvulus.

  8. La transferencia en el proceso educativo

    Directory of Open Access Journals (Sweden)

    Libia Elena Ramírez Robledo

    2011-01-01

    Full Text Available Este artículo pretende realizar una reflexión en torno a la transferencia como concepto nodal para pensar el proceso educativo. La autora utiliza como método el rastreo documental para conceptualizar la transferencia y hacer un análisis del rol docente desde las particularidades de dicho concepto y la teoría que lo soporta: la transferencia imaginaria y la simbólica, su relación con  los ideales y con labor pedagógica. La autora concluye que la labor docente debe hacerse desde la transferencia simbólica y que el docente debe estar muy atento a las inmersiones de su propia historia subjetiva en la relación con el estudiante. © Revista Colombiana de Ciencias Sociales.

  9. MEMORIA VISUAL COMO PARTE DEL PROCESO LECTOR

    OpenAIRE

    Gamero-Muñiz, Antonia

    2013-01-01

    Este trabajo tiene como objetivo indagar la relación entre los movimientos sacádicos, velocidad y comprensión lectora y la memoria visual en alumnos de 2ºESO, con el propósito de contribuir a la labor docente en los apoyos del aprendizaje de una correcta lectura y tomando como fundamentación teórica la importancia de la memoria visual en el proceso lector. Se ha seleccionado una muestra de 24 niños y 21 niñas con edades comprendidas entre 13 y 15 años. Se evaluaron los movimientos sacádico...

  10. fluidizado por proceso autotérmico

    Directory of Open Access Journals (Sweden)

    ZULAMITA ZAPATA BENABITHE

    2005-01-01

    Full Text Available El presente trabajo se basa en el estudio de la producción de carbón activado a partir de carbón mineral subbituminoso en un reactor de lecho fluidizado por proceso autotérmico. El carbón utilizado provino de la región de Amagá (Antioquia - Colombia y fue activado en dos reactores de lecho fluidizado de diferente diámetro interno, 10 cm y 22 cm. Los valores del área superficial específica y el volumen de poro de las muestras activadas fueron determinados a partir de las isotermas de N2 y CO2. Los resultados experimentales mostraron que los valores de áreas superficiales BET y DR y del Índice de Yodo se encontraron alrededor de 460 m2/g (SBET, 490 m2/g (SDR y 460 mg I2/g carbón.

  11. Small intestinal transplantation.

    LENUS (Irish Health Repository)

    Quigley, E M

    2012-02-03

    The past few years have witnessed a considerable shift in the clinical status of intestinal transplantation. A great deal of experience has been gained at the most active centers, and results comparable with those reported at a similar stage in the development of other solid-organ graft programs are now being achieved by these highly proficient transplant teams. Rejection and its inevitable associate, sepsis, remain ubiquitous, and new immunosuppressant regimes are urgently needed; some may already be on the near horizon. The recent success of isolated intestinal grafts, together with the mortality and morbidity attendant upon the development of advanced liver disease related to total parenteral nutrition, has prompted the bold proposal that patients at risk for this complication should be identified and should receive isolated small bowel grafts before the onset of end-stage hepatic failure. The very fact that such a suggestion has begun to emerge reflects real progress in this challenging field.

  12. Efecto de la aplicación de la vacuna antirrábica en canes vacunados durante la campaña de vacunación antirrábica masiva en Lima, Perú en 1993

    Directory of Open Access Journals (Sweden)

    Augusto Rodríguez

    2011-01-01

    Full Text Available En el presente trabajo se determinó la respuesta inmune posterior a las campañas de vacunación antirrábica masiva realizadas en 19 distritos de la ciudad de Lima. El método utilizado fue la titulación de anticuerpos antirrábicos mediante la prueba de seroneutralización en ratón, técnica que fue aplicado a un muestreo significativo de sueros sanguíneos de la población de canes vacunados. Se tomaron al azar 54 muestras de canes mordedores que ingresaron al Centro Antirrábico de Lima para ser observados clínicamente por un periodo de 10 días. De las 54 muestras de suero que se sometieron a la prueba, 28 (52% fueron positivos (títulos de 0,5-8,39 UI/ml, mientras que las 26 (48% muestras restantes dieron títulos inferiores a 0,5 UI/ml y otros fueron negativos a la prueba. El grupo etáreo de mayor muestreo correspondió a la población de canes de más riesgo (1-3 años de edad. En este grupo etáreo, 14 canes (26% presentaron sueros con títulos de protección, mientras que en 18 canes (33% la prueba fue negativa. En lo referente al sexo, el grupo de canes machos (considerados de mayor riesgo presentaron mayor número de individuos (44 canes respecto al grupo de hembras (10 canes y solo en 24 canes machos (45% dieron títulos de protección antirrábica. En conclusión, podemos decir que el 52% de canes vacunados durante las anteriores campañas de vacunación antirrábica masiva en la ciudad de Lima, en 1993, tuvieron títulos de anticuerpos protectores contra el virus de la rabia.

  13. Colgajo libre osteoseptocutáneo de peroné en la reconstrucción primaria de la radionecrosis masiva mandibular Fibular osteoseptocutaneous free flap in the primary reconstruction after massive radionecrosis of the mandible

    Directory of Open Access Journals (Sweden)

    P. Infante Cossío

    2004-06-01

    Full Text Available Resumen: Una de las complicaciones más serias del uso de la radioterapia en el tratamiento del carcinoma epidermoide de la cavidad oral, es la osteorradionecrosis. En este trabajo, presentamos cuatro pacientes afectos de osteorradionecrosis masiva de la mandíbula que habían fracasado inicialmente con medidas conservadoras y que fueron tratados con resección radical y reconstrucción primaria con un colgajo libre osteoseptocutáneo de peroné. El defecto mandibular tras la resección ósea midió una media de 10 cm e incluyó mucosa intraoral, piel o ambos. En dos casos de reconstrucción, se empleó el colgajo libre de peroné con doble paleta para reconstruir defectos extensos intra y extraorales. Se realizaron osteotomías en el peroné vascularizado en todos los casos para recrear el contorno mandibular. Todos los colgajos sobrevivieron completamente. Tres pacientes curaron primariamente con buenos resultados estéticos y funcionales. Una paciente falleció en el primer mes tras la operación por una pancreatitis aguda y fallo renal. En un paciente se han insertado implantes osteointegrados. En nuestra experiencia, el colgajo libre osteoseptocutáneo de peroné puede ser una opción ideal para la reconstrucción en un solo tiempo de defectos complejos mandibulares compuestos en pacientes afectos de osteorradionecrosis masiva.Abstract: Osteoradionecrosis is one of the most serious complications after radiation therapy of squamous carcinoma of the oral cavity. In this article, we report four cases of massive osteoradionecrosis of the mandible, all of whom had failed initial conservative management and treated with radical resection and primary reconstructed with fibular osteoseptocutaneous free flap. Mandible defects after radical resection were around 10 cm long and included intraoral mucosa, skin or both. A doubled-paddle peroneal tissue transfer was used in two cases for reconstruction of an extensive extra- or intraoral defects. The

  14. Mejora de los procesos cognitivos y discapacidad intelectual

    OpenAIRE

    Grau Rubio, Claudia

    2006-01-01

    Se describen las principales dificultades en los procesos cognitivos básicos (percepción, atención, memoria, procesos ejecutivos) y las actividades y programas para mejorarlos. Asimismo, se describen las dificultades de algunos síndromes que cursan discapacidad intelectual.

  15. Procesos matrimoniales y mediación familiar

    OpenAIRE

    Fernández López, Mercedes

    2012-01-01

    Presentación de la regulación de los procesos matrimoniales y de las posibilidades de acudir a la mediación familiar como medio para alcanzar acuerdos que eviten el proceso contradictorio. Momentos procesales en los que procede acudir a la mediación familiar.

  16. Lipo sarcoma in small intestine

    International Nuclear Information System (INIS)

    Rodriguez Iglesias, J.; Pineyro Gutierrez, A.; Taroco Medeiros, L.; Fein Kolodny, C.; Navarrete Pedocchi, H.

    1987-01-01

    A case is presented by primitive liposarcoma in small intestine , an extensive bibliographical review foreigner and national in this case. It detach the exceptional of the intestinal topography of the liposarcomas; and making stress in the relative value of the computerized tomography and ultrasonography in the diagnose of the small intestine tumors . As well as in the sarcomas of another topography, chemo and radiotherapy associated to the exeresis surgery, it can be of benefit [es

  17. Intestinal parasites : associations with intestinal and systemic inflammation

    NARCIS (Netherlands)

    Zavala, Gerardo A; García, Olga P; Camacho, Mariela; Ronquillo, Dolores; Campos-Ponce, Maiza; Doak, Colleen; Polman, Katja; Rosado, Jorge L

    2018-01-01

    AIMS: Evaluate associations between intestinal parasitic infection with intestinal and systemic inflammatory markers in school-aged children with high rates of obesity. METHODS AND RESULTS: Plasma concentrations of CRP, leptin, TNF-α, IL-6 and IL-10 were measured as systemic inflammation markers and

  18. Trayectorias industriales metropolitanas: nuevos procesos, nuevos contrastes

    Directory of Open Access Journals (Sweden)

    Inmaculada Caravaca

    2003-08-01

    Full Text Available La realidad industrial y urbana ha estado sometida a un fuerte proceso de reestructuración durante las últimas décadas. En la primera mitad de la década de los ‘80, conceptos como los de desindustrialización, o postindustrialización fueron asociados a los de desurbanización o contraurbanización. Sólo unos años más tarde el discurso empezó a ser radicalmente distinto al confirmarse la permanencia de fuertes externalidades positivas urbano-metropolitanas, y volvieron a considerarse tales ámbitos como ganadores. Las páginas que siguen intentarán sintetizar algunas de esas transformaciones que conocen las empresas y los espacios industriales metropolitanos en los últimos añosUrban and industrial reality has undergone a strong process of restructuring during the last decades. In the first half of the 80’s, concepts like de-industrialization or post-industrialization were associated with those of de-urbanization or counter-urbanization. Only a few years later the argument became to be radically different after the confirmation of strong positive urban-metropolitan externalities, and urban areas turned back to be considered as winning spaces. The following pages will try to summarize some of these transformations, which metropolitan firms and industrial areas have experimented in the last years

  19. El arbitraje en los procesos concursales

    Directory of Open Access Journals (Sweden)

    Carlos Molina-Sandoval

    2010-03-01

    Full Text Available El arbitraje ha asumido una gran importancia práctica en los últimos tiempos. Su utilización, como cualquier otro proceso o negocio jurídico, no es ajena a la situación de insolvencia de las partes, aun cuando este mismo estado impregna todo el haz de relaciones patrimoniales. Pese a ello, en la mayoría de las legislaciones comparadas las leyes concursales no han tenido  una  adecuada  evolución  normativa  que sea receptiva a las directrices  fundantes del esquema arbitral, y  se han mantenido bajo el velo de  concepciones  decimonónicas  que hoy  no  están  vigentes. Paralelamente, y dado que los principios que generalmente gobiernan el ordenamiento concursal están muy enraizados con la idea de orden público o interés general, la libertad de diagramación de los métodos de composición de controversias se encuentra limita­ da, por cuanto el fallido ha quedado desapoderado y, generalmente, pierde su legitimación procesal.

  20. Small Intestine Cancer—Health Professional Version

    Science.gov (United States)

    Adenocarcinoma is the most common type of small intestine cancer. Other types of small intestine cancer are sarcomas, carcinoid tumors, gastrointestinal stromal tumors, and lymphomas. Find evidence-based information on small intestine cancer treatment, research, and statistics.

  1. Hippo signalling directs intestinal fate

    DEFF Research Database (Denmark)

    le Bouteiller, Marie Catherine M; Jensen, Kim Bak

    2015-01-01

    Hippo signalling has been associated with many important tissue functions including the regulation of organ size. In the intestinal epithelium differing functions have been proposed for the effectors of Hippo signalling, YAP and TAZ1. These are now shown to have a dual role in the intestinal...

  2. Modelo de Proceso de Conceptualización de Requisitos

    Directory of Open Access Journals (Sweden)

    Alejandro Hossian

    2013-06-01

    Full Text Available El proceso de captura de requisitos constituye un proceso con connotaciones sociales relacionadas con diferentes personas (stakeholders, una circunstancia que hace que se presenten ciertos problemas cuando se lleva adelante la conceptualización de requisitos. En este trabajo se propone un Proceso de Conceptualización de Requisitos que se estructura en dos fases: (a Análisis Orientado a al Problema: cuyo objetivo es comprender el problema dado por el usuario en el dominio en el que este se lleva a cabo, y (b Análisis de Orientado al Producto: cuyo objetivo es obtener las funcionalidades que el usuario espera del producto de software a desarrollar, teniendo en cuenta la relación de estas con la realidad expresada por el usuario en su discurso. Se proponen seis técnicas que articulan cada una de las tareas que componen las fases de proceso propuesto.

  3. Bolivia: Del “proceso de cambio” a los cambios en el proceso

    Directory of Open Access Journals (Sweden)

    Jenny Ybarnegaray Ortiz

    2011-11-01

    Full Text Available Este artículo ofrece un análisis detallado del conflicto en torno al TIPNIS desde la perspectiva de una consultora independiente y activista cultural radicada en Bolivia. En su desarrollo, el artículo contextualiza históricamente el conflicto del TIPNIS y lo sitúa dentro del proceso social y político que hoy vive Bolivia. La autora se detiene en el análisis de “lo que revela el conflicto” y en los desafíos políticos que le plantea al gobierno del MAS, problematizando sustancialmente el  “proceso de cambio” anunciado el año 2005, durante la campaña electoral que condujo a Evo Morales a la Presidencia de Bolivia.        This article offers a detailed analysis of the conflict around the TIPNIS from the point of view of an independent consultant and cultural activist based in Bolivia. In its development, the article historically contextualizes the conflict of the TIPNIS locating it within the social and political process that today lives Bolivia. The author pauses in the analysis of “which substantially reveals the conflict” and in the political challenges that it poses to the government of the MAS, problematizing the “process of change” announced in 2005, during the electoral campaign that lead to Evo Morales to the Presidency of Bolivia. 

  4. [Treatment of children with intestinal failure: intestinal rehabilitation, home parenteral nutrition or small intestine transplantation?

    NARCIS (Netherlands)

    Neelis, E.G.; Oers, H.A. van; Escher, J.C.; Damen, G.M.; Rings, E.H.; Tabbers, M.M.

    2014-01-01

    Intestinal failure is characterised by inadequate absorption of food or fluids, which is caused by insufficient bowel surface area or functioning. Children with chronic intestinal failure are dependent on parenteral nutrition (PN), which can be provided at home (HPN). In the Netherlands, HPN for

  5. Viabilidad de huevos y modelo de jaula para la cría artificial masiva de Anastrepha fraterculus (Diptera: Tephritidae Viability of eggs and screen cage model for mass artificial rearing of Anastrepha fraterculus (Diptera: Tephritidae

    Directory of Open Access Journals (Sweden)

    Juliana García

    2011-12-01

    Full Text Available El objetivo del presente trabajo fue determinar la viabilidad de huevos y el modelo de jaula apropiada para la cría artificial masiva de Anastrepha fraterculus (Wiedemann. Los resultados muestran que el periodo de máxima oviposición ocurre durante los primeros 10 días en jaulas modelo Mediana, lo cual permite obtener el volumen de huevos necesario para alimentar el pie de cría de A. fraterculus en una cría masiva. Considerando que se encontró relación positiva entre el volumen de huevos ovipositados y el porcentaje de eclosión de huevos, en un periodo de 21 días de colecta, este periodo coincide además con los valores de eclosión más altos. Entre los modelos de jaulas evaluadas: Mediana, Grande y Mission; el modelo Mediana mostró los mejores resultados al evaluar el número de ía con un valor promedio de 11,4. La jaula que mostró menores resultados fue el modelo Mission, con un valor promedio de 4,6 huevos/hembra/día. Las jaulas grandes mostraron valores menores a las jaulas Medianas, pero las diferencias fueron no significativas. Los buenos valores registrados en las jaulas Medianas posiblemente se deban a la estructura de la jaula, que presentó la cara interna dividida en muchos compartimientos, lo cual mejora la distribución de las moscas adultas y previene la mortalidad temprana por hacinamiento en la base o en el techo de la jaula.The aim of this study was to determine the viability of eggs and cage model suitable for artificial mass rearing of Anastrepha fraterculus (Wiedemann. The results show that the period of maximum oviposition occurs during the first 10 days in Medium cages which allows to obtain the necessary volume of eggs to feed the foot of rearing of A. fraterculus in a mass rearing. Considering that a positive relationship was found between the volume of eggs oviposited and the hatchability percentage in a period of 21 days of collection, this period coincides with the highest values of hatching. Among the

  6. Análisis de la seguridad integral en los procesos electorales: Caso proceso electoral 2017 de Ecuador

    Directory of Open Access Journals (Sweden)

    Jeffry Badí Quinteros Basantes

    2018-01-01

    Full Text Available En este documento se muestra un análisis de la seguridad integral del proceso electoral 2017 realizado en la República del Ecuador. Este estudio incluye los enfoques de seguridad que se llevaron a cabo en este proceso: seguridad de la información, seguridad física segmentada en seguridad a procesos electorales y seguridad de la ciudadanía. Se mostrarán los elementos en cada uno de estos ámbitos, su ejecución, los elementos principales y las instituciones de apoyo que colaboraron en la seguridad para poder mantener la paz e institucionalidad del país en el proceso electoral 2017, con el fin de que el Consejo Nacional Electoral pudiera cumplir con el mandato constitucional y respetar la voluntad de los ciudadanos

  7. La sentencia Schrems del Tribunal de Justicia de la Unión Europea: un paso firme en la defensa del derecho a la privacidad en el contexto de la vigilancia masiva transnacional

    Directory of Open Access Journals (Sweden)

    María Isabel Puerto

    2017-12-01

    Full Text Available Las filtraciones de Edward Snowden demostraron al mundo la existencia de programas de vigilancia masiva implementados por Estados Unidos y otros aliados. Tales programas, supuestamente, estaban dirigidos a la recopilación de información para la prevención y represión del terrorismo, pero en la práctica implicaron violaciones inaceptables al derecho fundamental a la privacidad no solo de ciudadanos estadounidenses, sino de otras nacionalidades. Diversos actores de las Naciones Unidas y otras organizaciones internacionales han reaccionado mediante la elaboración de informes que manifiestan una elevada preocupación por el fenómeno de la vigilancia transnacional de masas y que pretenden ensalzar el discurso de los derechos humanos como límite contra las injerencias en la privacidad. En este contexto, el Tribunal de Justicia de la Unión Europea pronunció en el año 2015 la sentencia Schrems que invalidó una decisión de la Comisión Europea sobre el Acuerdo de Puerto Seguro que regulaba la transferencia de datos personales desde la Unión Europea a Estados Unidos. Este trabajo analiza críticamente dicha sentencia, porque ofrece interesantes aportaciones para la protección de los derechos a la privacidad y la protección de los datos personales, habiéndose convertido en un leading case de referencia obligada para la resolución de casos similares.

  8. Algoritmo inteligente para evaluar el impacto de la introducción masiva de cocinas de inducción; Intelligent algorithm for evaluating the impact of the introduction of mass induction

    Directory of Open Access Journals (Sweden)

    Jorge Enrique Carrión González

    2015-09-01

    Full Text Available El Ministerio de Electricidad y Energía Renovable de Ecuador (MEER está implementando el plan nacional de coccióneficiente, en el país y en la región Sur. El plan se basa en reemplazar las cocinas que usan gas licuado de petróleo (GLPpor cocinas eléctricas de inducción, estos cambios representan un aumento considerable en la demanda eléctrica delsector residencial. Los estudios de los sistemas eléctricos de distribución realizados permiten evaluar el comportamientoactual de las redes eléctricas y analizar futuros escenarios para poder determinar las mejoras de carácter técnico yorganizativo que deben introducirse. Seelaboró un algoritmo genético especializado para evaluar el efecto querepresenta en los transformadores de distribución la introducción masiva de las cocinas de inducción, con vistas aresolver el problema de un crecimiento brusco de la demanda de energía, minimizando los costos de inversión en nuevosequipos de transformación.The Ministry of Electricity and Renewable Energy of Ecuador (MEER is implement in the national plan for efficient cooking in thesouthern region and the country. The planes based on replacing kitchens using liquefied petroleum gas (LPG for induction cookers,representing an increase in electricity demanding the residential sector. Studies of electrical distribution systems made it possible toassess the current behavior of electrical networks and analyze future scenarios to determinism provident in technical and organizationalmeasures to be introduced. A genetic algorithm to evaluate the effect on distribution transformer soft he massive introduction ofinduction cookers, with view to resolving the problem of sharp growthin demand for energy while minimizing the costs of investment innew equipment was developed.

  9. Intestinal transplantation: The anesthesia perspective.

    Science.gov (United States)

    Dalal, Aparna

    2016-04-01

    Intestinal transplantation is a complex and challenging surgery. It is very effective for treating intestinal failure, especially for those patients who cannot tolerate parenteral nutrition nor have extensive abdominal disease. Chronic parental nutrition can induce intestinal failure associated liver disease (IFALD). According to United Network for Organ Sharing (UNOS) data, children with intestinal failure affected by liver disease secondary to parenteral nutrition have the highest mortality on a waiting list when compared with all candidates for solid organ transplantation. Intestinal transplant grafts can be isolated or combined with the liver/duodenum/pancreas. Organ Procurement and Transplantation Network (OPTN) has defined intestinal donor criteria. Living donor intestinal transplant (LDIT) has the advantages of optimal timing, short ischemia time and good human leukocyte antigen matching contributing to lower postoperative complications in the recipient. Thoracic epidurals provide excellent analgesia for the donors, as well as recipients. Recipient management can be challenging. Thrombosis and obstruction of venous access maybe common due to prolonged parenteral nutrition and/or hypercoaguability. Thromboelastography (TEG) is helpful for managing intraoperative product therapy or thrombosis. Large fluid shifts and electrolyte disturbances may occur due to massive blood loss, dehydration, third spacing etc. Intestinal grafts are susceptible to warm and cold ischemia and ischemia-reperfusion injury (IRI). Post-reperfusion syndrome is common. Cardiac or pulmonary clots can be monitored with transesophageal echocardiography (TEE) and treated with recombinant tissue plasminogen activator. Vasopressors maybe used to ensure stable hemodynamics. Post-intestinal transplant patients may need anesthesia for procedures such as biopsies for surveillance of rejection, bronchoscopy, endoscopy, postoperative hemorrhage, anastomotic leaks, thrombosis of grafts etc. Asepsis

  10. Impact of Intestinal Microbiota on Intestinal Luminal Metabolome

    Science.gov (United States)

    Matsumoto, Mitsuharu; Kibe, Ryoko; Ooga, Takushi; Aiba, Yuji; Kurihara, Shin; Sawaki, Emiko; Koga, Yasuhiro; Benno, Yoshimi

    2012-01-01

    Low–molecular-weight metabolites produced by intestinal microbiota play a direct role in health and disease. In this study, we analyzed the colonic luminal metabolome using capillary electrophoresis mass spectrometry with time-of-flight (CE-TOFMS) —a novel technique for analyzing and differentially displaying metabolic profiles— in order to clarify the metabolite profiles in the intestinal lumen. CE-TOFMS identified 179 metabolites from the colonic luminal metabolome and 48 metabolites were present in significantly higher concentrations and/or incidence in the germ-free (GF) mice than in the Ex-GF mice (p metabolome and a comprehensive understanding of intestinal luminal metabolome is critical for clarifying host-intestinal bacterial interactions. PMID:22724057

  11. Megacystis microcolon intestinal hypoperistalsis syndrome

    Science.gov (United States)

    Hiradfar, Mehran; Shojaeian, Reza; Dehghanian, Paria; Hajian, Sara

    2013-01-01

    Megacystis microcolon intestinal hypoperistalsis syndrome (MMIHS) is a multisystemic disorder in which impaired intestinal motor activity causes recurrent symptoms of intestinal obstruction in the absence of mechanical occlusion, associated with bladder distention without distal obstruction of the urinary tract. MMIHS and prune belly syndrome may overlap in most of the clinical features and discrimination of these two entities is important because the prognosis, management and consulting with parents are completely different. MMIHS outcome is very poor and in this article we present two neonates with MMIHS that both died in a few days. PMID:23729700

  12. Antibiotic concentrations in intestinal mucosa.

    Science.gov (United States)

    Malmborg, A S

    1985-01-01

    The concentrations in the intestinal mucosa after the initial dose of cefoxitin, piperacillin and clindamycin have been studied. The antibiotics were given at the induction of anesthesia as prophylaxis to patients undergoing elective colorectal surgery. The concentrations of the antibiotics in serum and intestinal mucosa taken during the operation were determined by the microbiological agar diffusion method. Therapeutic concentrations in intestinal mucosa were maintained during the major part of the operation period. The mean mucosa/serum concentration ratios were for cefoxitin 0.4, for piperacillin 0.5 and for clindamycin 1.2.

  13. INFANTS’ INTESTINAL COLICS. MODERN DATA

    Directory of Open Access Journals (Sweden)

    N.I. Ursova

    2011-01-01

    Full Text Available The article analyzes modern data on infants’ intestinal colics. Peculiarities of nutrition, intestinal microbiocenose in healthy infants, methods of colcs’ correction are discussed. Author describes the principles of probiotics choice based on their clinical effectiveness in infants. Milk formula «Nan Comfort» can be useful in prophylaxis and treatment of functional disorders of gastrointestinal tract in children.Key words: infants, gastrointestinal tract, anatomy, physiology, intestinal colics, nutrition, probiotics.(Voprosy sovremennoi pediatrii — Current Pediatrics. 2011; 10 (2: 125–131

  14. Intestinal Failure (Short Bowel Syndrome)

    Science.gov (United States)

    ... at the beginning to maintain nutrition and good hydration although it is hoped that the small intestine ... life. For more information or to locate a pediatric gastroenterologist in your area please visit our website ...

  15. INTESTINAL INTUSSUSCEPTION DUE TO CONCURRENT ...

    African Journals Online (AJOL)

    Administrator

    Hymenolepis nana and Dentostomella ... worms (H. nana and D. translucida) were observed in the lumen of the intestine with severe cellular infiltration .... helminthosis and Balantidosis in Red monkey (Erythrocebus patas) in Ibadan Nigeria Nigerian ...

  16. Telescoping Intestine in an Adult

    Directory of Open Access Journals (Sweden)

    Khaldoon Shaheen

    2013-01-01

    Full Text Available Protrusion of a bowel segment into another (intussusception produces severe abdominal pain and culminates in intestinal obstruction. In adults, intestinal obstruction due to intussusception is relatively rare phenomenon, as it accounts for minority of intestinal obstructions in this population demographic. Organic lesion is usually identifiable as the cause of adult intussusceptions, neoplasms account for the majority. Therefore, surgical resection without reduction is almost always necessary and is advocated as the best treatment of adult intussusception. Here, we describe a rare case of a 44-year-old male with a diffuse large B-cell lymphoma involving the terminal ileum, which had caused ileocolic intussusception and subsequently developed intestinal obstruction requiring surgical intervention. This case emphasizes the importance of recognizing intussusception as the initial presentation for bowel malignancy.

  17. Intestinal actinomycosis: a case report

    International Nuclear Information System (INIS)

    Loureiro, C.M.; Labrunie, E.; Pannaim, V.L.N.; Santos, A.A.S. dos; Pereira, A.A.

    1989-01-01

    Intestinal actinomycosis: a case report. The authors describe a case of intestinal actinomycosis, which was manisfestated by abdominal mass and suggested, clinical and radiologically, a bowel carcinoma. They discuss the pathogenesis, and the clinical and radiological manisfestations of this disease, and its differential diagnosis. This is an infrequent disease which must be considered whenever suggestive clinical aspects are associated with a radiological ''malignant pattern'' of a bowel lesion. (author) [pt

  18. Parenteral Nutrition and Intestinal Failure.

    Science.gov (United States)

    Bielawska, Barbara; Allard, Johane P

    2017-05-06

    Severe short bowel syndrome (SBS) is a major cause of chronic (Type 3) intestinal failure (IF) where structural and functional changes contribute to malabsorption and risk of micronutrient deficiencies. Chronic IF may be reversible, depending on anatomy and intestinal adaptation, but most patients require long-term nutritional support, generally in the form of parenteral nutrition (PN). SBS management begins with dietary changes and pharmacologic therapies taking into account individual anatomy and physiology, but these are rarely sufficient to avoid PN. New hormonal therapies targeting intestinal adaptation hold promise. Surgical options for SBS including intestinal transplant are available, but have significant limitations. Home PN (HPN) is therefore the mainstay of treatment for severe SBS. HPN involves chronic administration of macronutrients, micronutrients, fluid, and electrolytes via central venous access in the patient's home. HPN requires careful clinical and biochemical monitoring. Main complications of HPN are related to venous access (infection, thrombosis) and metabolic complications including intestinal failure associated liver disease (IFALD). Although HPN significantly impacts quality of life, outcomes are generally good and survival is mostly determined by the underlying disease. As chronic intestinal failure is a rare disease, registries are a promising strategy for studying HPN patients to improve outcomes.

  19. Primary intestinal lymphangiectasia: Minireview

    Science.gov (United States)

    Ingle, Sachin B; Hinge (Ingle), Chitra R

    2014-01-01

    Primary idiopathic intestinal lymphangiectasia is an unusual disease featured by the presence of dilated lymphatic channels which are located in the mucosa, submucosa or subserosa leading to protein loosing enteropathy.Most often affected were children and generally diagnosed before third year of life but may be rarely seen in adults too. Bilateral pitting oedema of lower limb is the main clinical manifestation mimicking the systemic disease and posing a real diagnostic dilemma to the clinicians to differentiate it from other common systemic diseases like Congestive cardiac failure, Nephrotic Syndrome, Protein Energy Malnutrition, etc. Diagnosis can be made on capsule endoscopy which can localise the lesion but unable to take biopsy samples. Thus, recently double-balloon enteroscopy and biopsy in combination can be used as an effective diagnostic tool to hit the correct diagnosis. Patients respond dramatically to diet constituting low long chain triglycerides and high protein content with supplements of medium chain triglyceride. So early diagnosis is important to prevent untoward complications related to disease or treatment for the sake of accurate pathological diagnosis. PMID:25325063

  20. [Malaria and intestinal protozoa].

    Science.gov (United States)

    Rojo-Marcos, Gerardo; Cuadros-González, Juan

    2016-03-01

    Malaria is life threatening and requires urgent diagnosis and treatment. Incidence and mortality are being reduced in endemic areas. Clinical features are unspecific so in imported cases it is vital the history of staying in a malarious area. The first line treatments for Plasmodium falciparum are artemisinin combination therapies, chloroquine in most non-falciparum and intravenous artesunate if any severity criteria. Human infections with intestinal protozoa are distributed worldwide with a high global morbid-mortality. They cause diarrhea and sometimes invasive disease, although most are asymptomatic. In our environment populations at higher risk are children, including adopted abroad, immune-suppressed, travelers, immigrants, people in contact with animals or who engage in oral-anal sex. Diagnostic microscopic examination has low sensitivity improving with antigen detection or molecular methods. Antiparasitic resistances are emerging lately. Copyright © 2016 Elsevier España, S.L.U. y Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.

  1. Haemorrhage and intestinal lymphoma

    Directory of Open Access Journals (Sweden)

    Attilia M. Pizzini

    2013-04-01

    Full Text Available Background: The prevalence of coeliac disease is around 1% in general population but this is often unrecognised. The classical presentation of adult coeliac disease is characterized by diarrhoea and malabsorption syndrome, but atypical presentations are probably more common and are characterized by iron deficiency anaemia, weight loss, fatigue, infertility, arthralgia, peripheral neuropathy and osteoporosis. Unusual are the coagulation disorders (prevalence 20% and these are due to vitamin K malabsorption (prolonged prothrombin time. Clinical case: A 64-year-old man was admitted to our Department for an extensive spontaneous haematoma of the right leg. He had a history of a small bowel resection for T-cell lymphoma, with a negative follow-up and he didn’t report any personal or familiar history of bleeding. Laboratory tests showed markedly prolonged prothrombin (PT and partial-thromboplastin time (PTT, corrected by mixing studies, and whereas platelet count and liver tests was normal. A single dose (10 mg of intravenous vitamin K normalized the PT. Several days before the patient had been exposed to a superwarfarin pesticide, but diagnostic tests for brodifacoum, bromadiolone or difenacoum were negative. Diagnosis of multiple vitamin K-dependent coagulationfactor deficiencies (II, VII, IX, X due to intestinal malabsorption was made and coeliac disease was detected. Therefore the previous lymphoma diagnosis might be closely related to coeliac disease. Conclusions: A gluten free diet improves quality of life and restores normal nutritional and biochemical status and protects against these complications.

  2. Adult intestinal failure

    Energy Technology Data Exchange (ETDEWEB)

    Davidson, J., E-mail: Jdavidson@doctors.org.u [Salford Royal Hospital, Salford (United Kingdom); Plumb, A.; Burnett, H. [Salford Royal Hospital, Salford (United Kingdom)

    2010-05-15

    Intestinal failure (IF) is the inability of the alimentary tract to digest and absorb sufficient nutrition to maintain normal fluid balance, growth, and health. It commonly arises from disease affecting the mesenteric root. Although severe IF is usually managed in specialized units, it lies at the end of a spectrum with degrees of nutritional compromise being widely encountered, but commonly under-recognized. Furthermore, in the majority of cases, the initial enteric insult occurs in non-specialist IF centres. The aim of this article is to review the common causes of IF, general principles of its management, some commoner complications, and the role of radiology in the approach to a patient with severe IF. The radiologist has a crucial role in helping provide access for feeding solutions (both enteral and parenteral) and controlling sepsis (via drainage of collections) in an initial restorative phase of treatment, whilst simultaneously mapping bowel anatomy and quality, and searching for disease complications to assist the clinicians in planning a later, restorative phase of therapy.

  3. El proceso reproductivo: Algunas consideraciones sobre el maternaje

    Directory of Open Access Journals (Sweden)

    Ignacio González Labrador

    2001-10-01

    Full Text Available Se realizaron una serie de consideraciones generales sobre el proceso reproductivo, y como una consecuencia de él se consolida un proceso llamado maternaje, conceptualizándose según criterio del autor, cómo puede influir en la vida sexual de la mujer. Se conceptualiza según las letras que componen la palabra que denomina dicho procesoA series of general considerations on the reproductive process as a result of which the so-called motherhood process is strengthened were presented in this paper. The author conceptualizes the influence of this process on the woman’s sexual life. The conceptualization is based on the letters of the word defining such a process

  4. «Proceso de la literatura» peruana

    OpenAIRE

    Rovira Soler, José Carlos

    2009-01-01

    José Carlos Mariátegui revisa y actualiza en 1928 la mirada sobre la literatura peruana en un texto, «Proceso de la literatura», el último de los 7 ensayos de interpretación de la realidad peruana, a través del cual se conforma una nueva visión del complejo proceso de formación de la literatura nacional. La reflexión de Mariátegui resulta un hito imprescindible en el debate cultural de principios de siglo XX sobre la identidad peruana y una respuesta fundamental a las controversias suscitadas...

  5. en los procesos de investigación

    Directory of Open Access Journals (Sweden)

    José Arias Ordóñez

    2007-01-01

    Full Text Available El artículo presenta, inicialmente, dos enfoques de la gestión del conocimiento; posteriormente, muestra el desarrollo y la transformación de los procesos de creación de conocimiento y cómo con la apropiación y aplicación de teorías de gestión administrativa, la gestión del conocimiento se convierte en un intangible clave para las organizaciones; finalmente, se discuten algunos aspectos de la aplicación de un modelo de gestión del conocimiento en procesos de investigación.

  6. Los usos del testimonio en los estudios de la memoria. El caso de las violaciones masivas a los derechos humanos en la Argentina (Testimony uses in memory studies. The case of gross violations to human rights in Argentina

    Directory of Open Access Journals (Sweden)

    Julieta Mira

    2017-12-01

    Full Text Available The memory study as an interdisciplinary field in Latin-America has been constructing and consolidating from the nineties of the 20th Century; which gained a driving force from the need to approach the topics regarding the political violence and the massive human rights violations perpetrated by the last military dictatorships. The testimony emerges as a favoured source from which reconstruct the memory of diverse historical-political events, as those linked with gross human rights violations. Taking in advance this challenging opportunity, the research work with testimony requires the comprehension of the sense and the uses, the scope and the limitations of the actors´ (survivors speech as witnesses of violence. This article proposes itself a complex and critical approach to the testimony from a methodological perspective, focused in the case of the last Argentine dictatorship (1976-1983.El campo interdisciplinario de estudio sobre la memoria en Latinoamérica se fue conformando y consolidando desde los años noventa del siglo XX; el cual fue impulsado desde la necesidad de abordar las temáticas relativas a la violencia política y a las violaciones masivas a los derechos humanos en las últimas dictaduras militares. El testimonio emerge como una fuente privilegiada a partir de la cual reconstruir la memoria de diversos sucesos histórico-políticos, como aquellos vinculados a graves violaciones a los derechos humanos. Ante esta desafiante oportunidad, el trabajo de investigación con el testimonio precisa la comprensión del sentido y de los usos, del alcance y de las limitaciones de la palabra de los actores que fueron testigos (supervivientes de violencia. Este artículo se propone desde una mirada metodológica un acercamiento complejo y crítico al testimonio haciendo foco en el caso de la última dictadura militar en la Argentina (1976-1983. DOWNLOAD THIS PAPER FROM SSRN: http://ssrn.com/abstract=3055033

  7. Primary intestinal lymphangiectasia (Waldmann's disease).

    Science.gov (United States)

    Vignes, Stéphane; Bellanger, Jérôme

    2008-02-22

    Primary intestinal lymphangiectasia (PIL) is a rare disorder characterized by dilated intestinal lacteals resulting in lymph leakage into the small bowel lumen and responsible for protein-losing enteropathy leading to lymphopenia, hypoalbuminemia and hypogammaglobulinemia. PIL is generally diagnosed before 3 years of age but may be diagnosed in older patients. Prevalence is unknown. The main symptom is predominantly bilateral lower limb edema. Edema may be moderate to severe with anasarca and includes pleural effusion, pericarditis or chylous ascites. Fatigue, abdominal pain, weight loss, inability to gain weight, moderate diarrhea or fat-soluble vitamin deficiencies due to malabsorption may also be present. In some patients, limb lymphedema is associated with PIL and is difficult to distinguish lymphedema from edema. Exsudative enteropathy is confirmed by the elevated 24-h stool alpha1-antitrypsin clearance. Etiology remains unknown. Very rare familial cases of PIL have been reported. Diagnosis is confirmed by endoscopic observation of intestinal lymphangiectasia with the corresponding histology of intestinal biopsy specimens. Videocapsule endoscopy may be useful when endoscopic findings are not contributive. Differential diagnosis includes constrictive pericarditis, intestinal lymphoma, Whipple's disease, Crohn's disease, intestinal tuberculosis, sarcoidosis or systemic sclerosis. Several B-cell lymphomas confined to the gastrointestinal tract (stomach, jejunum, midgut, ileum) or with extra-intestinal localizations were reported in PIL patients. A low-fat diet associated with medium-chain triglyceride supplementation is the cornerstone of PIL medical management. The absence of fat in the diet prevents chyle engorgement of the intestinal lymphatic vessels thereby preventing their rupture with its ensuing lymph loss. Medium-chain triglycerides are absorbed directly into the portal venous circulation and avoid lacteal overloading. Other inconsistently effective

  8. Primary intestinal lymphangiectasia (Waldmann's disease

    Directory of Open Access Journals (Sweden)

    Bellanger Jérôme

    2008-02-01

    Full Text Available Abstract Primary intestinal lymphangiectasia (PIL is a rare disorder characterized by dilated intestinal lacteals resulting in lymph leakage into the small bowel lumen and responsible for protein-losing enteropathy leading to lymphopenia, hypoalbuminemia and hypogammaglobulinemia. PIL is generally diagnosed before 3 years of age but may be diagnosed in older patients. Prevalence is unknown. The main symptom is predominantly bilateral lower limb edema. Edema may be moderate to severe with anasarca and includes pleural effusion, pericarditis or chylous ascites. Fatigue, abdominal pain, weight loss, inability to gain weight, moderate diarrhea or fat-soluble vitamin deficiencies due to malabsorption may also be present. In some patients, limb lymphedema is associated with PIL and is difficult to distinguish lymphedema from edema. Exsudative enteropathy is confirmed by the elevated 24-h stool α1-antitrypsin clearance. Etiology remains unknown. Very rare familial cases of PIL have been reported. Diagnosis is confirmed by endoscopic observation of intestinal lymphangiectasia with the corresponding histology of intestinal biopsy specimens. Videocapsule endoscopy may be useful when endoscopic findings are not contributive. Differential diagnosis includes constrictive pericarditis, intestinal lymphoma, Whipple's disease, Crohn's disease, intestinal tuberculosis, sarcoidosis or systemic sclerosis. Several B-cell lymphomas confined to the gastrointestinal tract (stomach, jejunum, midgut, ileum or with extra-intestinal localizations were reported in PIL patients. A low-fat diet associated with medium-chain triglyceride supplementation is the cornerstone of PIL medical management. The absence of fat in the diet prevents chyle engorgement of the intestinal lymphatic vessels thereby preventing their rupture with its ensuing lymph loss. Medium-chain triglycerides are absorbed directly into the portal venous circulation and avoid lacteal overloading. Other

  9. COMUNICACIÓN EN PROCESOS DE TRABAJO

    Directory of Open Access Journals (Sweden)

    María Dolores Gil Montelongo

    2009-09-01

    Hidden="false" UnhideWhenUsed="false" QFormat="true" Name="Subtle Emphasis" />

    Se propone un modelo de comunicación que desarrolla un procedimiento, el cual,  apoyándose en los mapas de proceso y los diagramas de flujo informativo, permite establecer las matrices de comunicación para desarrollar las interacciones entre actividades y procesos, y mejorar los resultados.  Lograr este propósito puede conformar el inicio de la construcción de un modelo de comunicación organizacional

  10. Isotopic identification of intestinal strangulation

    International Nuclear Information System (INIS)

    Anderson, M.C.; Selby, J.B.

    1982-01-01

    A small series of eleven dogs prepared with a strangulating segment of jejunum demonstrated that a radionuclide, 99 mTc-labelled albumin, concentrates in the lumen and bowel wall of the affected intestinal segment. Modern scanning equipment accurately localized the strangulating loop. This technique has the potential of identifying patients with intestinal obstruction, in whom strangulation is a factor, prior to the development of impaired arterial inflow and frank gangrene. These findings confirmed earlier obstructions that were reported when nuclear scanning instrumentation was less sophisticated. Identification of patients at risk for intestinal strangulation requires a high index of suspicion. Excruciating cramping abdominal pain out of proportion to physical findings, roentgenogram evidence, and laboratory studies should alert the physician to the possibility of intestinal ischemia and closed loop obstruction. Radionuclide scanning in such cases may be of assistance in defining or excluding the diagnosis of a strangulating mechanism. The test is simple, relatively economical, and represents a low risk procedure to patients. It would have no place when the classic physical and laboratory findings of intestinal infarction are present

  11. Intestinal circulation during inhalation anesthesia

    International Nuclear Information System (INIS)

    Tverskoy, M.; Gelman, S.; Fowler, K.C.; Bradley, E.L.

    1985-01-01

    This study was designed to evaluate the influence of inhalational agents on the intestinal circulation in an isolated loop preparation. Sixty dogs were studied, using three intestinal segments from each dog. Selected intestinal segments were pumped with aortic blood at a constant pressure of 100 mmHg. A mixture of 86 Rb and 9-microns spheres labeled with 141 Ce was injected into the arterial cannula supplying the intestinal loop, while mesenteric venous blood was collected for activity counting. A very strong and significant correlation was found between rubidium clearance and microsphere entrapment (r = 0.97, P less than 0.0001). Nitrous oxide anesthesia was accompanied by a higher vascular resistance (VR), lower flow (F), rubidium clearance (Cl-Rb), and microspheres entrapment (Cl-Sph) than pentobarbital anesthesia, indicating that the vascular bed in the intestinal segment was constricted and flow (total and nutritive) decreased. Halothane, enflurane, and isoflurane anesthesia were accompanied by a much lower arteriovenous oxygen content difference (AVDO 2 ) and oxygen uptake than pentobarbital or nitrous oxide. Compared with pentobarbital, enflurane anesthesia was not accompanied by marked differences in VR, F, Cl-Rb, and Cl-Sph; halothane at 2 MAC decreased VR and increased F and Cl-Rb while isoflurane increased VR and decreased F. alpha-Adrenoceptor blockade with phentolamine (1 mg . kg-1) abolished isoflurane-induced vasoconstriction, suggesting that the increase in VR was mediated via circulating catecholamines

  12. [Primary intestinal lymphangiectasia (Waldmann's disease)].

    Science.gov (United States)

    Vignes, S; Bellanger, J

    2017-08-31

    Primary intestinal lymphangiectasia (PIL), Waldmann's disease, is a rare disorder of unknown etiology characterized by dilated intestinal lacteals leading to lymph leakage into the small-bowel lumen and responsible for protein-losing enteropathy leading to lymphopenia, hypoalbuminemia and hypogammaglobulinemia. PIL is generally diagnosed before 3 years of age but may be diagnosed in older patients. The main symptom is bilateral lower limb edema. Edema may be moderate to severe including pleural effusion, pericarditis or ascites. Protein-losing enteropathy is confirmed by the elevated 24-h stool α1-antitrypsin clearance and diagnosis by endoscopic observation of intestinal lymphangiectasia with the corresponding histology of biopsies. Videocapsule endoscopy may be useful when endoscopic findings are not contributive. Several B-cell lymphomas of the gastrointestinal tract or with extra-intestinal localizations were reported in PIL patients. A long-term strictly low-fat diet associated with medium-chain triglyceride and liposoluble vitamin supplementation is the cornerstone of PIL medical management. Octreotide, a somatostatin analog, have been proposed with an inconsistent efficacy in association with diet. Surgical small-bowel resection is useful in the rare cases with segmental and localized intestinal lymphangiectasia. A prolonged clinical and biological follow-up is recommended. Copyright © 2017 Société Nationale Française de Médecine Interne (SNFMI). Published by Elsevier SAS. All rights reserved.

  13. Parenteral nutrition in intestinal failure

    Directory of Open Access Journals (Sweden)

    Kurkchubasche AG

    2015-01-01

    Full Text Available Arlet G Kurkchubasche,1 Thomas J Herron,2 Marion F Winkler31Department of Surgery and Pediatrics, 2Department of Surgery, Alpert Medical School of Brown University, 3Department of Surgery/Nutritional Support Service, Rhode Island Hospital, Providence, RI, USAAbstract: Intestinal failure is a consequence of extensive surgical resection resulting in anatomic loss and/or functional impairment in motility or absorptive capacity. The condition is clinically characterized by the inability to maintain fluid, energy, protein, electrolyte, or micronutrient balance when on a conventionally accepted, normal diet. Parenteral nutrition (PN is the cornerstone of management until intestinal adaptation returns the patient to a PN-independent state. Intestinal length, residual anatomic segments and motility determine the need for and duration of parenteral support. The goals of therapy are to provide sufficient nutrients to enable normal growth and development in children, and support a healthy functional status in adults. This review addresses indications for PN, the formulation of the PN solution, patient monitoring, and considerations for prevention of PN-associated complications. With the ultimate goal of achieving enteral autonomy, the important role of diet, pharmacologic interventions, and surgery is discussed.Keywords: intestinal failure, short-bowel syndrome, parenteral nutrition, home nutrition support, intestinal rehabilitation

  14. Small intestinal sulphoxidation of albendazole.

    Science.gov (United States)

    Villaverde, C; Alvarez, A I; Redondo, P; Voces, J; Del Estal, J L; Prieto, J G

    1995-05-01

    1. The in vitro sulphoxidation of Albendazole (ABZ) by rat intestinal microsomes has been examined. The results revealed intestinal sulphoxidation of ABZ by intestinal microsomes in a NADPH-dependent enzymatic system. The kinetic constants for sulphoxidase activity were Vmax = 46 pmol/min/mg protein and Michaelis constant Km = 6.8 microM. 2. The possible effect of inducers (Arochlor 1254 and ABZ pretreatment) and inhibitors (erythromycin, methimazole, carbon monoxide and fenbendazole), was also studied. In rat pretreated with Arochlor 1254, Vmax was 52 pmol/min/mg protein, whereas oral administration of ABZ increased the intestinal sulphoxidation of the drug, Vmax being 103 pmol/min/mg protein. 3. Erythromycin did not change the enzymatic bioconversion of ABZ, but methimazole and carbon monoxide inhibited the enzyme activity by approximately 60 and 30% respectively. Fenbendazole (a structural analogue of ABZ) was a competitive inhibitor of the sulphoxidation process, characterized by a Ki or 69 microM. 4. These data demonstrate that the intestinal enzymes contributing to the initial sulphoxidation of ABZ may be similar to the hepatic enzymes involved in the biotransformation process by the P450 and FMO systems, a conclusion that needs to be further established.

  15. Isotopic identification of intestinal strangulation

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, M.C.; Selby, J.B.

    1982-12-01

    A small series of eleven dogs prepared with a strangulating segment of jejunum demonstrated that a radionuclide, /sup 99/mTc-labelled albumin, concentrates in the lumen and bowel wall of the affected intestinal segment. Modern scanning equipment accurately localized the strangulating loop. This technique has the potential of identifying patients with intestinal obstruction, in whom strangulation is a factor, prior to the development of impaired arterial inflow and frank gangrene. These findings confirmed earlier obstructions that were reported when nuclear scanning instrumentation was less sophisticated. Identification of patients at risk for intestinal strangulation requires a high index of suspicion. Excruciating cramping abdominal pain out of proportion to physical findings, roentgenogram evidence, and laboratory studies should alert the physician to the possibility of intestinal ischemia and closed loop obstruction. Radionuclide scanning in such cases may be of assistance in defining or excluding the diagnosis of a strangulating mechanism. The test is simple, relatively economical, and represents a low risk procedure to patients. It would have no place when the classic physical and laboratory findings of intestinal infarction are present.

  16. Proceso contencioso-administrativo: emplazamiento personal de los codemandados

    OpenAIRE

    Gascón Inchausti, Fernando

    1998-01-01

    Comentario a la Sentencia del Tribunal Constitucional 192/1997, de 11 de noviembre de 1997, acerca de la necesidad de que todos los sujetos que reciben la consideración legal de codemandados en un proceso contencioso-administrativo sean emplazados personalmente.

  17. Desarrollo de simuladores para procesos industriales. Parte I. (Colada continua

    Directory of Open Access Journals (Sweden)

    Ramírez, A.

    2006-06-01

    Full Text Available This work was written for illustrating the development of computer simulators for production process. As an example a simulator for continuous casting process was made, this is the most popular method to produce some steel products like billets and slabs. The simulator (SSCC was programmed by the present authors in C++; but mathematical procedures, algorithms and flow charts shown here can be used as a base in any other programming language. This is the first part of the work; it is focused to the development of some computational tools to describe the real continuous casting process

    Este trabajo se realiza con el objeto de ilustrar el desarrollo de simuladores para procesos industriales; como ejemplo se realizó un sistema de simulación para representar el proceso de colada continua que es el proceso más común para la producción de perfiles de acero. El sistema de simulación para colada continua (SSCC fue programado por los presentes autores en lenguaje C++; sin embargo, los procedimientos matemáticos, algoritmos y diagramas de flujo ilustrados en este trabajo pueden ser programados en cualquier lenguaje de programación. Esta primera parte del trabajo se enfoca a desarrollar herramientas de cálculo para representar lo que sucede físicamente durante el proceso de colada continua.

  18. Procesos de soldadura aplicados en la construccion naval.

    OpenAIRE

    Pacheco Guillen, Victor

    2015-01-01

    El presente trabajo, tiene como propósito mostrar los distintos métodos que existen para realizar trabajos de corte y soldadura submarina. Para ello, se explican los procesos de funcionamiento, así como las herramientas que se utilizan, las técnicas de uso, precauciones y aplicaciones.

  19. Intestinal Microbiota Influences Non-intestinal Related Autoimmune Diseases

    Science.gov (United States)

    Opazo, Maria C.; Ortega-Rocha, Elizabeth M.; Coronado-Arrázola, Irenice; Bonifaz, Laura C.; Boudin, Helene; Neunlist, Michel; Bueno, Susan M.; Kalergis, Alexis M.; Riedel, Claudia A.

    2018-01-01

    The human body is colonized by millions of microorganisms named microbiota that interact with our tissues in a cooperative and non-pathogenic manner. These microorganisms are present in the skin, gut, nasal, oral cavities, and genital tract. In fact, it has been described that the microbiota contributes to balancing the immune system to maintain host homeostasis. The gut is a vital organ where microbiota can influence and determine the function of cells of the immune system and contributes to preserve the wellbeing of the individual. Several articles have emphasized the connection between intestinal autoimmune diseases, such as Crohn's disease with dysbiosis or an imbalance in the microbiota composition in the gut. However, little is known about the role of the microbiota in autoimmune pathologies affecting other tissues than the intestine. This article focuses on what is known about the role that gut microbiota can play in the pathogenesis of non-intestinal autoimmune diseases, such as Grave's diseases, multiple sclerosis, type-1 diabetes, systemic lupus erythematosus, psoriasis, schizophrenia, and autism spectrum disorders. Furthermore, we discuss as to how metabolites derived from bacteria could be used as potential therapies for non-intestinal autoimmune diseases. PMID:29593681

  20. Intestinal Microbiota Influences Non-intestinal Related Autoimmune Diseases

    Directory of Open Access Journals (Sweden)

    Maria C. Opazo

    2018-03-01

    Full Text Available The human body is colonized by millions of microorganisms named microbiota that interact with our tissues in a cooperative and non-pathogenic manner. These microorganisms are present in the skin, gut, nasal, oral cavities, and genital tract. In fact, it has been described that the microbiota contributes to balancing the immune system to maintain host homeostasis. The gut is a vital organ where microbiota can influence and determine the function of cells of the immune system and contributes to preserve the wellbeing of the individual. Several articles have emphasized the connection between intestinal autoimmune diseases, such as Crohn's disease with dysbiosis or an imbalance in the microbiota composition in the gut. However, little is known about the role of the microbiota in autoimmune pathologies affecting other tissues than the intestine. This article focuses on what is known about the role that gut microbiota can play in the pathogenesis of non-intestinal autoimmune diseases, such as Grave's diseases, multiple sclerosis, type-1 diabetes, systemic lupus erythematosus, psoriasis, schizophrenia, and autism spectrum disorders. Furthermore, we discuss as to how metabolites derived from bacteria could be used as potential therapies for non-intestinal autoimmune diseases.

  1. Gintonin absorption in intestinal model systems

    Directory of Open Access Journals (Sweden)

    Byung-Hwan Lee

    2018-01-01

    Conclusion: The present study shows that gintonin could be absorbed in the intestine through transcellular and paracellular diffusion, and active transport. In addition, the lipid component of gintonin might play a key role in its intestinal absorption.

  2. Therapeutic hypothermia reduces intestinal ischemia/reperfusion ...

    African Journals Online (AJOL)

    The detached intestinal epithelial cells in hypothermia group showed ... of apoptosis than those in normothermia group at 4 h (17.30 ± 2.56 vs. ... intestinal ischemia/reperfusion (IR) injury, which could be attenuated by therapeutic hypothermia.

  3. Update on small intestinal stem cells

    OpenAIRE

    Tesori, Valentina; Puglisi, Maria Ausiliatrice; Lattanzi, Wanda; Gasbarrini, Giovanni Battista; Gasbarrini, Antonio

    2013-01-01

    Among somatic stem cells, those residing in the intestine represent a fascinating and poorly explored research field. Particularly, somatic stem cells reside in the small intestine at the level of the crypt base, in a constant balance between self-renewal and differentiation. Aim of the present review is to delve into the mechanisms that regulate the delicate equilibrium through which intestinal stem cells orchestrate intestinal architecture. To this aim, special focus will be addressed to id...

  4. Intestinal epithelium in inflammatory bowel disease

    DEFF Research Database (Denmark)

    Coskun, Mehmet

    2014-01-01

    The intestinal epithelium has a strategic position as a protective physical barrier to luminal microbiota and actively contributes to the mucosal immune system. This barrier is mainly formed by a monolayer of specialized intestinal epithelial cells (IECs) that are crucial in maintaining intestinal...... of inflammatory bowel disease (IBD). Understanding the role of the intestinal epithelium in IBD pathogenesis might contribute to an improved knowledge of the inflammatory processes and the identification of potential therapeutic targets....

  5. Exercise and the gastro-intestinal tract

    African Journals Online (AJOL)

    on perfonnance and me value of cardiovascular training in improving performance in aerobic sports is well recognised. The role of me gastro-intestinal tracr, bom as a limiting and sustaining facror in aerobic exercises, is less well appreciared. Gastro-intestinal symptoms. The spectrum of gastro-intestinal effecrs of exercise ...

  6. The mucosal firewalls against commensal intestinal microbes.

    Science.gov (United States)

    Macpherson, Andrew J; Slack, Emma; Geuking, Markus B; McCoy, Kathy D

    2009-07-01

    Mammals coexist with an extremely dense microbiota in the lower intestine. Despite the constant challenge of small numbers of microbes penetrating the intestinal surface epithelium, it is very unusual for these organisms to cause disease. In this review article, we present the different mucosal firewalls that contain and allow mutualism with the intestinal microbiota.

  7. INTESTINAL PERMEABILITY IN PEDIATRIC GASTROENTEROLOGY

    NARCIS (Netherlands)

    VANELBURG, RM; UIL, JJ; DEMONCHY, JGR; HEYMANS, HSA

    1992-01-01

    The role of the physiologic barrier function of the small bowel and its possible role in health and disease has attracted much attention over the past decade. The intestinal mucosal barrier for luminal macromolecules and microorganism is the result of non-immunologic and immunologic defense

  8. Drug Transporters in the Intestine

    DEFF Research Database (Denmark)

    Steffansen, Bente

    2016-01-01

    to the intestinal exsorptive DTs. An example is the API sulfasalazine, which is a substrate for breast cancer resistance protein (BCRP)/ABCG2. Sulfasalazine absorption is found to increase when human volunteers are administered high concentrations together with the inhibitor and spice curcumin. In conclusion...

  9. Radiology of the small intestine

    International Nuclear Information System (INIS)

    Trueber, E.; Engelbrecht, V.

    1998-01-01

    The book presents the state of the art in radiology of the small intestine, discussing diagnostic fundamentals in the general, introductory chapter and continuing with the specific modalities available and applicable for diagnostic evaluation of the various symptoms and lesions. (orig./CB) [de

  10. Circadian disorganization alters intestinal microbiota.

    Directory of Open Access Journals (Sweden)

    Robin M Voigt

    Full Text Available Intestinal dysbiosis and circadian rhythm disruption are associated with similar diseases including obesity, metabolic syndrome, and inflammatory bowel disease. Despite the overlap, the potential relationship between circadian disorganization and dysbiosis is unknown; thus, in the present study, a model of chronic circadian disruption was used to determine the impact on the intestinal microbiome. Male C57BL/6J mice underwent once weekly phase reversals of the light:dark cycle (i.e., circadian rhythm disrupted mice to determine the impact of circadian rhythm disruption on the intestinal microbiome and were fed either standard chow or a high-fat, high-sugar diet to determine how diet influences circadian disruption-induced effects on the microbiome. Weekly phase reversals of the light:dark (LD cycle did not alter the microbiome in mice fed standard chow; however, mice fed a high-fat, high-sugar diet in conjunction with phase shifts in the light:dark cycle had significantly altered microbiota. While it is yet to be established if some of the adverse effects associated with circadian disorganization in humans (e.g., shift workers, travelers moving across time zones, and in individuals with social jet lag are mediated by dysbiosis, the current study demonstrates that circadian disorganization can impact the intestinal microbiota which may have implications for inflammatory diseases.

  11. Milk products and intestinal health

    NARCIS (Netherlands)

    Van der Meer, R; Bovee-Oudenhoven, IMJ; Sesink, ALA; Kleibeuker, JH

    Milk products may improve intestinal health by means of the cytoprotective effects of their high calcium phosphate (CaPi) content. We hypothesized that this cytoprotection may increase host defenses against bacterial infections as well as decrease colon cancer risk. This paper summarizes our studies

  12. Hirschsprung's disease - Postsurgical intestinal dysmotility

    OpenAIRE

    Romaneli, Mariana Tresoldi das Neves; Ribeiro, Antonio Fernando; Bustorff-Silva, Joaquim Murray; de Carvalho, Rita Barbosa; Lomazi, Elizete Aparecida

    2016-01-01

    Abstract Objective: To describe the case of an infant with Hirschsprung's disease presenting as total colonic aganglionosis, which, after surgical resection of the aganglionic segment persisted with irreversible functional intestinal obstruction; discuss the difficulties in managing this form of congenital aganglionosis and discuss a plausible pathogenetic mechanism for this case. Case description: The diagnosis of Hirschsprung's disease presenting as total colonic aganglionosis was establi...

  13. Intestinal Volvulus in Idiopathic Steatorrhea

    Science.gov (United States)

    Warner, H. A.; Kinnear, D. G.; Cameron, D. G.

    1963-01-01

    Volvulus of the intestine has recently been observed in three patients with idiopathic steatorrhea in relapse. Two patients gave a history of intermittent abdominal pain, distension and obstipation. Radiographic studies during these attacks revealed obstruction at the level of the sigmoid colon. Reduction under proctoscopic control was achieved in one instance, spontaneous resolution occurring in the other. The third patient presented as a surgical emergency and underwent operative reduction of a small intestinal volvulus. Persistence of diarrhea and weight loss postoperatively led to further investigation and a diagnosis of idiopathic steatorrhea. In all cases, treatment resulted in clinical remission with a coincident disappearance of obstructive intestinal symptoms. The pathogenesis of volvulus in sprue is poorly understood. Atonicity and dilatation of the bowel and stretching of the mesentery likely represent important factors. The symptoms of recurrent abdominal pain and distension in idiopathic steatorrhea necessitate an increased awareness of intestinal volvulus as a complication of this disease. ImagesFig. 1Fig. 2Fig. 3Figs. 4 and 5Fig. 6 PMID:13998948

  14. Diversity of insect intestinal microflora

    Czech Academy of Sciences Publication Activity Database

    Mrázek, Jakub; Štrosová, Lenka; Fliegerová, Kateřina; Kott, T.; Kopečný, Jan

    2008-01-01

    Roč. 53, č. 3 (2008), s. 229-233 ISSN 0015-5632 R&D Projects: GA ČR GA303/06/0974 Institutional research plan: CEZ:AV0Z50450515 Keywords : insect intestinal microflora Subject RIV: EE - Microbiology, Virology Impact factor: 1.172, year: 2008

  15. Microcontainers for Intestinal Drug Delivery

    DEFF Research Database (Denmark)

    Tentor, Fabio; Mazzoni, Chiara; Keller, Stephan Sylvest

    Among all the drug administration routes, the oral one is the most preferred by the patients being less invasive, faster and easier. Oral drug delivery systems designed to target the intestine are produced by powder technology and capsule formulations. Those systems including micro- and nano...

  16. Producción masiva y simultánea de machos de Ceratitis capitata (Diptera: Tephritidae y parasitoides Dichasmimorpha longicaudata (Hymenoptera: Braconidae Massive and simultaneous production of Ceratitis capitata (Diptera: Tephritidae males and Diachasmimorpha longicaudata (Hymenoptera: Braconidae parasitoids

    Directory of Open Access Journals (Sweden)

    Silvia N. López

    2006-12-01

    Full Text Available En la línea de sexado genético «Cast191» las hembras de Ceratitis capitata son homocigotas para el gen slow , lo que reduce su velocidad de desarrollo; los machos son heterocigotas y muestran una velocidad de desarrollo normal. Esta característica permitió producir, con Cast191, machos estériles por un lado, y parasitoides criados sobre las larvas remanentes por el otro. Nuestro objetivo con este trabajo fue producir ambos insumos simultáneamente y a una escala mayor que hasta ahora. Además, bajo estas condiciones, y en un intento por aumentar la separación entre sexos, se aplicó a las larvas del primer estadío un pulso de 15º C, durante 1 ó 2 días, luego del cual se las mantuvo a 20º C ó 25º C, hasta que entraron al estado de pupa, luego se mantuvo todo el material a 25º C. La mejor separación de sexos, lograda con el tratamiento a 20º C sin pulso de frío, se usó para comparar la calidad del parasitoide Diachasmimorpha longicaudata, criado sobre las larvas obtenidas tras la separación de los machos, con aquellos criados sobre la línea salvaje. Para ello, este tratamiento de separación fue aplicado en la cría de la mosca, y el material remanente de dieta con larvas fue expuesto al parasitoide. La tasa de parasitismo obtenida fue semejante a la hallada sobre la línea salvaje, y la tasa sexual de la F 1 del parasitoide presentó un sesgo hacia las hembras aún mayor. Se discute la factibilidad de utilizar la línea Cast191 de C. Capitata, para la producción a mayor escala de machos de mosca y para la cría masiva del parasitoide D. longicaudata.In the genetic sexing strain «Cast191», the females of Ceratitis capitata are homozygous for the mutation slow , slowing down their rate of development, and the males are heterozygous, having a normal rate of development. This feature made Cast191 capable of producing sterile males, on one hand, and parasitoids that are reared on the remaining larvae, on the other. The

  17. Prenatal intestinal volvulus: look for cystic fibrosis.

    Science.gov (United States)

    Chouikh, Taieb; Mottet, Nicolas; Cabrol, Christelle; Chaussy, Yann

    2016-12-21

    Intestinal volvulus is a life-threatening emergency requiring prompt surgical management. Prenatal intestinal volvulus is rare, and most are secondary to intestinal atresia, mesenteric defect or without any underlying cause. Cystic fibrosis (CF) is known to cause digestive tract disorders. After birth, 10-15% of newborns with CF may develop intestinal obstruction within a few days of birth because of meconial ileus. 1 This obstruction is a result of dehydrated thickened meconium obstructing the intestinal lumen. We report two cases of fetuses with prenatal diagnosis of segmental volvulus in whom CF was diagnosed. 2016 BMJ Publishing Group Ltd.

  18. Microbiota intestinal, probióticos y prebióticos

    Directory of Open Access Journals (Sweden)

    Carlos David Castañeda Guillot

    2017-12-01

    Full Text Available La microbiota intestinal es el elemento fundamental del “Ecosistema Intestinal”, cuyas acciones tienen un efecto beneficioso para la salud, al participar de forma activa en los procesos de digestión de nutrientes asociado a sus mecanismos sobre la homeostasis y la inmunidad del intestino. Los probióticos y prebióticos juegan un rol decisivo en la modulación de la microbiota intestinal y han demostrado sus beneficios para el tratamiento de distintas enfermedades intestinales y extra-intestinales. Se realizó una búsqueda en bases documentales de PubMed, SciELO y Latindex de publicaciones relacionadas con la microbiota intestinal, probióticos y prebióticos hasta el 30 junio 2017. Son actualizados los criterios relacionados con las funciones de la microbiota intestinal, el proceso de implantación a partir del nacimiento, el desarrollo acelerado en su composición, los distintos factores que influencian en su diversidad y estabilidad para mantener un estado de eubiosis en el curso de la vida. El desequlibrio de la misma (disbiosis es un elemento de importancia en la producción de afecciones intestinales y extra-intestinales agudas y crónicas. Se revisaron los probióticos y prebióticos, sus ventajas, tipos, indicaciones y las formas de obtención de los prebióticos. El papel de la microbiota intestinal como órgano metabólico por sus múltiples funciones, en especial la homeostasis e inmunidad intestinal y sus beneficios para la salud son revisados. La participación de los probióticos y prebióticos como terapéutica y sus efectos en enfermedades intestinales y extra-intestinales relacionadas con la microbiota y su modulación son examinados por su importancia en la práctica médica.

  19. A etiological factors in mechanical intestinal obstruction

    International Nuclear Information System (INIS)

    Asad, S.; Khan, H.; Khan, I.A.; Ghaffar, S.; Rehman, Z.U.

    2012-01-01

    Background: Intestinal obstruction occurs when the normal flow of intestinal contents is interrupted. The most frequent causes of intestinal obstruction are postoperative adhesions and hernias, which cause extrinsic compression of the intestine. Less frequently, tumours or strictures of the bowel can cause intrinsic blockage. Objective of the study was to find out the various a etiological factors of mechanical intestinal obstruction and to evaluate the morbidity and mortality in adult patients presenting to Surgical 'A' unit of Ayub teaching hospital with mechanical intestinal obstruction. Methods: This cross-sectional study was conducted from March 2009 to September, 2009. All patients presenting with intestinal obstruction and were above the age of 12 years were included in the study. Patients with non-mechanical obstruction were excluded from the study and those who responded to conservative measures were also excluded. Results: A total of 36 patients with age ranging from 12 to 80 years (Mean age 37.72+-19.74 years) and male to female ratio of 1.77:1, were treated for mechanical intestinal obstruction. The most common cause for mechanical intestinal obstruction was adhesions (36.1%). Intestinal tuberculosis was the second most common cause (19.4%), while hernias and sigmoid volvulus affected 13.9% patients each. Malignancies were found in 5.6% cases. Conclusion: Adhesions and Tuberculosis are the leading causes of mechanical intestinal obstruction in Pakistan. Although some patients can be treated conservatively, a substantial portion requires immediate surgical intervention. (author)

  20. Intestinal perfusion in the study of intestinal absorption

    International Nuclear Information System (INIS)

    Baker, S.J.

    1976-01-01

    Several techniques for studying absorption by means of intestinal perfusion have been developed. While the principle is simple, the practice is complicated by absorption of the solvent and by excretion of fluid into the lumen. To improve reliability a ''marker'' is incorporated into the system; it should behave as nearly as possible like the nutrient of interest, except that it should be unabsorbable. A great many markers, including several labelled with radionuclides, have been developed for use with numerous nutrients, and perfusion methods using double or triple tubes or occlusive balloons have been tested. The perfusion technique is too complicated for routine diagnostic use, but it offers at present the only possibility of studying the function of defined sections of the small intestine in the intact human. (author)

  1. The CT signs of intestinal volvulus

    International Nuclear Information System (INIS)

    Ji Jiansong; Wang Zufei; Xu Zhaolong; Lv Guijian; Xu Min; Zhao Zhongwei; Su Jinliang; Zhou Limin

    2005-01-01

    Objective: To improve the accuracy rate of spiral CT diagnosing intestinal volvulus. Methods: To analysis the CT findings of 9 cases of intestinal volvulus proved by operation, the main reconstruction techniques were multiplanar reformation (MPR) and sliding thin-slab maximum intensity projection (STS-MIP). Results: All the 9 cases were diagnosed accurately, the main signs were 'whirlpool' of intestine (6 cases) and vessels (9 cases),'target loop' (2 cases),'beak'(6 cases). Conclusion: 'Whirlpool' of vessels is a specific sign to diagnose intestinal volvulus, 'target loop', reduced enhancement of intestinal wall and ascites are the reliable signs to strangulated intestinal obstruction. Spiral CT and reconstructions have important value to diagnose the intestinal volvulus. (authors)

  2. La Universidad del Zulia frente al proceso de transformación organizacional. Perspectiva de algunos actores del proceso

    Directory of Open Access Journals (Sweden)

    Juliana Ferrer

    2002-01-01

    Full Text Available La gerencia universitaria de hoy, requiere asumir un proceso de transformación organizacional, que le permita describir un equilibrio entre su identidad institucional y los cambios sustanciales exigidos desde todos sus ámbitos, a fin de mejorar los procesos académicos, cohesionar con éxito las funciones básicas y por ende lograr la calidad académica deseada. Surge como inquietud el presente artículo el cual pretende indagar sobre algunos esfuerzos que la Universidad del Zulia ha adelantado en este sentido, pero sobre todo hacer énfasis en la perspectiva de algunos actores del proceso, representados por el personal docente y de investigación, que para el período 2000-2001 se desempeño como personal directivo Para la recolección de los datos se asumió en primer término la técnica cualitativa del grupo focal, permitiendo así lograr suficiente información para aplicar luego, una muestra probabilística que arrojó un tamaño de 39 unidades con un nivel de confianza del 95%. Se concluye que los gerentes universitarios están conscientes de los problemas de carácter operativo que obstaculizan el proceso de cohesión exitosa de las funciones básicas. Sin embargo, no evidencian conocimiento exhaustivo sobre el desarrollo de procesos gerenciales, para el logro de los cursos de acción enunciados por esos mismos actores. Se recomienda sobre la necesidad de formar una gerencia universitaria sólida, en el compromiso de la labor constante en materia de información y conocimiento, de tal forma que los cambios implantados sean percibidos de manera objetiva, internalizados y compartidos por la comunidad universitaria, en la búsqueda de que ellos se conviertan en piezas del proceso de cambio institucional.

  3. Escalonando la agroecologia : Procesos y aprendizajes de cuatro ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    1 janv. 2007 ... Escalonando la agroecologia : Procesos y aprendizajes de cuatro experiencias en Chile, Cuba, Honduras y Perú ... Carlos Venegas est directeur régional pour le Centro de Educación y Tecnología (CET) et coordonne le programme d'études de premier cycle sur l'agronomie et le développement rural ...

  4. Modelización global del proceso de colada continua

    Directory of Open Access Journals (Sweden)

    Barco, J.

    2005-12-01

    Full Text Available In the continuous casting process the contribution of complicated physical phenomena has an important effect in the final quality of the product and productivity of the process. Moreover, the different physical phenomena do not act in isolation, they interact in a coupled way affecting the quality of the semiproduct. Therefore, a correct design and setting is a work that requires a good knowledge of the different phenomena that are present and their interactions. In this work, a simulation methodology that solves all the process as a whole is presented, where the variables of the process are the only boundary conditions. The interactions between the different phenomena are solved with the use of commercial applications (FLUENT and ABAQUS and home developed models.

    En el proceso de colada continua contribuyen complicados fenómenos físicos con un marcado efecto en la calidad final del producto y en la productividad del proceso. Además, los distintos fenómenos físicos no aparecen de forma aislada, sino que interactúan unos con otros de manera acoplada, afectando a la calidad del semiproducto. El correcto diseño y ajuste es, por lo tanto, una tarea que requiere un gran conocimiento tanto de los distintos fenómenos que intervienen como de sus interacciones. En este trabajo se presenta un novedoso método de simulación que resuelve el proceso en su conjunto, siendo las variables del proceso las únicas condiciones de contorno. Mediante la utilización conjunta de herramientas comerciales (FLUENT y ABAQUS y una serie de modelos de desarrollo propio se resuelven las interacciones entre los distintos fenómenos.

  5. Procesos agroecológicos, en Ventaquemada Boyacá

    Directory of Open Access Journals (Sweden)

    Francisco Gracía

    2011-10-01

    Full Text Available La agroecología se debe entender como la interacción de factorespolíticos, sociales, culturales, económicos, medio ambientales, educativos y tecnológicos, así como de los procesos productivos que trazan el derrotero en el desarrollo de los pueblos. Mientras que la agricultura convencional estableció parámetros diferentesde producción, que alejaron la actividad agropecuaria del concepto de agroecología y la convirtieron en un negocio donde el deterioro de los recursos naturales es consecuencia del proceso productivo. De esta manera el presente trabajo busca identificar y analizar los contextos agroecológicos sucedidos en la vereda Supatá en Ventaquemada – Boyacá, que han influido en las familias. Para esto se establecieron como técnicas y herramientas la consulta dedocumentos estadísticos, talleres participativos, matriz (Dofa, mapeo, mapa de redes, matriz de plan acción, entrevistas semiestructuradas, observación no participante y diarios de campo. Así, se pudo establecer que las actividades agrícolas marcan el comportamiento de las personas, dejando notar que la agricultura de revolución verde, propuesta como proceso agroindustrial, promueve el individualismo a partir del monocultivo.

  6. The Contributions of Human Mini-Intestines to the Study of Intestinal Physiology and Pathophysiology.

    Science.gov (United States)

    Yu, Huimin; Hasan, Nesrin M; In, Julie G; Estes, Mary K; Kovbasnjuk, Olga; Zachos, Nicholas C; Donowitz, Mark

    2017-02-10

    The lack of accessibility to normal and diseased human intestine and the inability to separate the different functional compartments of the intestine even when tissue could be obtained have held back the understanding of human intestinal physiology. Clevers and his associates identified intestinal stem cells and established conditions to grow "mini-intestines" ex vivo in differentiated and undifferentiated conditions. This pioneering work has made a new model of the human intestine available and has begun making contributions to the understanding of human intestinal transport in normal physiologic conditions and the pathophysiology of intestinal diseases. However, this model is reductionist and lacks many of the complexities of normal intestine. Consequently, it is not yet possible to predict how great the advances using this model will be for understanding human physiology and pathophysiology, nor how the model will be modified to include multiple other intestinal cell types and physical forces necessary to more closely approximate normal intestine. This review describes recent studies using mini-intestines, which have readdressed previously established models of normal intestinal transport physiology and newly examined intestinal pathophysiology. The emphasis is on studies with human enteroids grown either as three-dimensional spheroids or two-dimensional monolayers. In addition, comments are provided on mouse studies in cases when human studies have not yet been described.

  7. Ultrasonographic Demonstration of Intestinal Obstruction

    International Nuclear Information System (INIS)

    Lee, Dong Hoo; Choi, Hyae Seoun; Kim, S. K.; Han, S.U.; Park, K. S.; Park, H. N.

    1982-01-01

    The cardinal feature of intestinal obstruction is the intraluminal fluid accumulation within the bowel segments. The presence of air simply makes it easier to find dilated fluid-filled bowel loop on plain radiographic films. Distended fluid-filed loop, however, may be obscure on X-ray film when gas is absent, secondary to vomiting, or to cessation of air swallowing. furthermore, in closed loop obstruction, air cannot enter the involved bowel, and thereby in this situation gray scale ultrasonography may be a useful device in making a rapid diagnosis. By sonographic confirmations of intestinal obstruction, a tonic, fluid-filled bowel loops usually were revealed as multiple, circular or cylindrical cystic structures with a finely irregular wall. Valvulae connivente sexhibit a characteristic key-board appearance when they project into the fluid-filled lumen

  8. The intestinal microenvironment in sepsis.

    Science.gov (United States)

    Fay, Katherine T; Ford, Mandy L; Coopersmith, Craig M

    2017-10-01

    The gastrointestinal tract has long been hypothesized to function as "the motor" of multiple organ dysfunction syndrome. The gastrointestinal microenvironment is comprised of a single cell layer epithelia, a local immune system, and the microbiome. These three components of the intestine together play a crucial role in maintaining homeostasis during times of health. However, the gastrointestinal microenvironment is perturbed during sepsis, resulting in pathologic changes that drive both local and distant injury. In this review, we seek to characterize the relationship between the epithelium, gastrointestinal lymphocytes, and commensal bacteria during basal and pathologic conditions and how the intestinal microenvironment may be targeted for therapeutic gain in septic patients. Published by Elsevier B.V.

  9. Teoría de restricciones para procesos de manufactura

    Directory of Open Access Journals (Sweden)

    Gabriela Villagómez

    2012-06-01

    Full Text Available La empresa “Productos Alexander” fabricante de snacks de la ciudad de Quito, tiene un sistema de producción que no permite el abastecimiento de los pedidos de sus clientes reflejando un índice de servicio al cliente de 89,58% ya que sus procesos están trabajando con capacidades que no se encuentran correctamente programadas, en vista de tal razón el objetivo de esta investigación es proponer un sistema de mejora continua con el fin de aumentar y efectivizar específicamente la producción de snacks de papas fritas utilizando la Teoría de Restricciones (TOC como metodología científica. Se realizó la medición de capacidad de cada una de las operaciones que componen el proceso de elaboración de snacks y se identificó la restricción en el proceso de fritura, que no estaba trabajando el 100% del tiempo en la jornada diaria limitando así la capacidad de la fábrica, por lo que se optó por explotar la restricción para eliminarla. La propuesta planteada para explotar la restricción consiste en una mejor programación de la producción, reducción de lote de transferencia de proceso a proceso, programación de la cantidad de trabajo para cada uno de los operarios en la jornada, la preparación del proceso y la fijación de turnos en la hora de almuerzo de los operarios lo que contribuye a agilizar el proceso de fritura y permitir que trabaje a su máxima capacidad el 100% del tiempo.Dicha propuesta se puede considerar como una solución al problema y así mejorar los niveles de producción de la empresa, tomando en cuenta que en base a los indicadores de TOC el Beneficio Neto de la empresa aumentaría de $15 333.09 a $ 17 392.14 al cumplir en cantidad y a tiempo todos los pedidos de los clientes.Abstract:The company "Products Alexander" snack manufacturer in the city of Quito, has a production system that cannot supply customer orders, with a customer service index of 89,58%, also their processes are working with capabilities that

  10. Colon in acute intestinal infection.

    Science.gov (United States)

    Guarino, Alfredo; Buccigrossi, Vittoria; Armellino, Carla

    2009-04-01

    The colon is actively implicated in intestinal infections not only as a target of enteric pathogens and their products but also as a target organ for treatment. In the presence of diarrhea, both of osmotic and secretory nature, the colon reacts with homeostatic mechanisms to increase ion absorption. These mechanisms can be effectively exploited to decrease fluid discharge. A model of intestinal infections using rotavirus (RV) in colonic cells was set up and used to define a dual model of secretory and osmotic diarrhea in sequence. Using this model, antidiarrheal drugs were tested, namely zinc and the enkephalinase inhibitor racecadotril. Zinc was able to decrease the enterotoxic activity responsible for secretory diarrhea. It also inhibited the cytotoxic effect of RV. The mechanism of zinc was related at least in part to the activation of MAPK activity, but also a direct antiviral effect was observed. Racecadotril showed a potent and selective inhibition of active secretion, being particularly effective in the first phase of RV diarrhea. The use of drugs active at the colonic level, therefore, offers effective options to treat intestinal infections in childhood. In addition, the colon is the natural site of colonic microflora, a target of probiotic therapy, which is the first line of approach recommended by the European Society for Paediatric Gastroenterology, Hepatology and Nutrition to treat infectious diarrhea.

  11. Radiological manifestations of intestinal tuberculosis

    International Nuclear Information System (INIS)

    Im, Jae Hoon

    1974-01-01

    Radiological findings of 87 cases of intestinal tuberculosis are analyzed and presented. The diagnosis was based on histopathology in 29 cases, and on clinical ground and radiological findings in 58 cases. The radio of male and female patients was 4:6, and peak incidence is between 10 and 30. Abdominal pain, diarrhea, weight loss, fever and general weakness are frequent symptoms, and tenderness of abdomen, ascites with abdominal distension, malnutrition and emaciation are frequent signs of the patients. Laboratory investigation reveal anemia, raised ESR, hypoalbuminaemia and positive occult blood reaction in the stool in most of the patients. Chest film show activity pulmonary tuberculosis in only 1/3 patients. There is no pathognomonic radiological findings in intestinal tuberculosis and their manifestations are protean, and differentiation from other inflammatory diseases and malignant tumors in gastrointestinal tract is very difficult on radiological ground alone. However, in patients with complaining vague abdominal symptoms and signs, the radiological diagnosis is most certain means in the decision of existence of organic lesion and suggestion of tuberculosis in the gastrointestinal tract and its extent as yet. Multiplicity of the lesion, involvement of adjacent organ such as peritoneum or mesenteric lymph nodes, typical nodularity or irregularity of mesenteric border and existence of active pulmonary tuberculosis are the suggestive findings of intestinal tuberculosis. In the diagnosis of inflammatory disease or malignant tumor of gastrointestinal tract, the possibility of tuberculosis should be borne in mind, and vice versa

  12. INTESTINAL MICROBIOTA IN DIGESTIVE DISEASES

    Directory of Open Access Journals (Sweden)

    Maria do Carmo Friche PASSOS

    2017-07-01

    Full Text Available ABSTRACT BACKGROUND In recent years, especially after the development of sophisticated metagenomic studies, research on the intestinal microbiota has increased, radically transforming our knowledge about the microbiome and its association with health maintenance and disease development in humans. Increasing evidence has shown that a permanent alteration in microbiota composition or function (dysbiosis can alter immune responses, metabolism, intestinal permeability, and digestive motility, thereby promoting a proinflammatory state. Such alterations can mainly impair the host’s immune and metabolic functions, thus favoring the onset of diseases such as diabetes, obesity, digestive, neurological, autoimmune, and neoplastic diseases. This comprehensive review is a compilation of the available literature on the formation of the complex intestinal ecosystem and its impact on the incidence of diseases such as obesity, non-alcoholic steatohepatitis, irritable bowel syndrome, inflammatory bowel disease, celiac disease, and digestive neoplasms. CONCLUSION: Alterations in the composition and function of the gastrointestinal microbiota (dysbiosis have a direct impact on human health and seem to have an important role in the pathogenesis of several gastrointestinal diseases, whether inflammatory, metabolic, or neoplastic ones.

  13. Radiological manifestations of intestinal tuberculosis

    Energy Technology Data Exchange (ETDEWEB)

    Im, Jae Hoon [Seoul National University College of Medicine, Seoul (Korea, Republic of)

    1974-10-15

    Radiological findings of 87 cases of intestinal tuberculosis are analyzed and presented. The diagnosis was based on histopathology in 29 cases, and on clinical ground and radiological findings in 58 cases. The radio of male and female patients was 4:6, and peak incidence is between 10 and 30. Abdominal pain, diarrhea, weight loss, fever and general weakness are frequent symptoms, and tenderness of abdomen, ascites with abdominal distension, malnutrition and emaciation are frequent signs of the patients. Laboratory investigation reveal anemia, raised ESR, hypoalbuminaemia and positive occult blood reaction in the stool in most of the patients. Chest film show activity pulmonary tuberculosis in only 1/3 patients. There is no pathognomonic radiological findings in intestinal tuberculosis and their manifestations are protean, and differentiation from other inflammatory diseases and malignant tumors in gastrointestinal tract is very difficult on radiological ground alone. However, in patients with complaining vague abdominal symptoms and signs, the radiological diagnosis is most certain means in the decision of existence of organic lesion and suggestion of tuberculosis in the gastrointestinal tract and its extent as yet. Multiplicity of the lesion, involvement of adjacent organ such as peritoneum or mesenteric lymph nodes, typical nodularity or irregularity of mesenteric border and existence of active pulmonary tuberculosis are the suggestive findings of intestinal tuberculosis. In the diagnosis of inflammatory disease or malignant tumor of gastrointestinal tract, the possibility of tuberculosis should be borne in mind, and vice versa.

  14. [Intestinal parasitic diseases in children].

    Science.gov (United States)

    Mare, Anca; Man, A; Toma, Felicia; Székely, Edit; Lôrinczi, Lilla; Sipoş, Anca

    2007-01-01

    To compare the incidence of intestinal parasitosis between children with residence in urban and rural areas: to compare the efficacy of parasitologic diagnostic methods. In our study we included two lots of children. The first lot consisted in 74 children from rural areas from which we collected 44 samples of feces and 55 samples for the "Scotch tape" test. The second lot consisted in 214 children from urban areas from which we collected 44 samples of feces. We examined each sample of feces by three different methods. The study was performed between April to June 2006. The incidence of intestinal parasitosis increases in children from urban areas towards rural areas, and in children between 5 and 10 years. Ascariasis is the most frequent disease in both urban and rural areas. By examination of each fecal sample by three different methods, the number of positive cases increased. The residence in rural areas and age between 5 to 10 years are risk factors for intestinal parasitosis. The "Scotch tape" test was more efficient in Enterobius vermicularis infection than the methods performed from feces. We recommend using at the same time three diagnostic methods for feces examination to improve the diagnostic sensibility.

  15. An intestinal Trojan horse for gene delivery.

    Science.gov (United States)

    Peng, Haisheng; Wang, Chao; Xu, Xiaoyang; Yu, Chenxu; Wang, Qun

    2015-03-14

    The intestinal epithelium forms an essential element of the mucosal barrier and plays a critical role in the pathophysiological response to different enteric disorders and diseases. As a major enteric dysfunction of the intestinal tract, inflammatory bowel disease is a genetic disease which results from the inappropriate and exaggerated mucosal immune response to the normal constituents in the mucosal microbiota environment. An intestine targeted drug delivery system has unique advantages in the treatment of inflammatory bowel disease. As a new concept in drug delivery, the Trojan horse system with the synergy of nanotechnology and host cells can achieve better therapeutic efficacy in specific diseases. Here, we demonstrated the feasibility of encapsulating DNA-functionalized gold nanoparticles into primary isolated intestinal stem cells to form an intestinal Trojan horse for gene regulation therapy of inflammatory bowel disease. This proof-of-concept intestinal Trojan horse will have a wide variety of applications in the diagnosis and therapy of enteric disorders and diseases.

  16. Epidermal Growth Factor and Intestinal Barrier Function

    Directory of Open Access Journals (Sweden)

    Xiaopeng Tang

    2016-01-01

    Full Text Available Epidermal growth factor (EGF is a 53-amino acid peptide that plays an important role in regulating cell growth, survival, migration, apoptosis, proliferation, and differentiation. In addition, EGF has been established to be an effective intestinal regulator helping to protect intestinal barrier integrity, which was essential for the absorption of nutrients and health in humans and animals. Several researches have demonstrated that EGF via binding to the EGF receptor and subsequent activation of Ras/MAPK, PI3K/AKT, PLC-γ/PKC, and STATS signal pathways regulates intestinal barrier function. In this review, the relationship between epidermal growth factor and intestinal development and intestinal barrier is described, to provide a better understanding of the effects of EGF on intestine development and health.

  17. Intestinal epithelium in inflammatory bowel disease

    Directory of Open Access Journals (Sweden)

    Mehmet eCoskun

    2014-08-01

    Full Text Available The intestinal epithelium has a strategic position as a protective physical barrier to luminal microbiota and actively contributes to the mucosal immune system. This barrier is mainly formed by a monolayer of specialized intestinal epithelial cells (IECs that are crucial in maintaining intestinal homeostasis. Therefore, dysregulation within the epithelial layer can increase intestinal permeability, lead to abnormalities in interactions between IECs and immune cells in underlying lamina propria, and disturb the intestinal immune homeostasis, all of which are linked to the clinical disease course of inflammatory bowel disease (IBD. Understanding the role of the intestinal epithelium in IBD pathogenesis might contribute to an improved knowledge of the inflammatory processes and the identification of potential therapeutic targets.

  18. PROCESOS DE EROSIÓN EN LOS BADLANDS ALICANTINOS

    Directory of Open Access Journals (Sweden)

    A. Cerdà i Bolinches

    1997-01-01

    Full Text Available Los procesos de erosión son muy activos en la provincia de Alicante debido a las reducidas e irregulares precipitaciones, al substrato altamente erosionable y al milenario uso antrópico. Estas condiciones dan lugar a la formación de zonas acarcavadas o badlands, los cuales contribuyen con elevados volúmenes de agua y sedimentos a los cauces. A partir de experimentos con lluvia simulada se estudian los procesos de erosión y se cuantifican sus tasas a escala de entre-regueros (< 1 m 2 en dos zonas de badlands típicos del territorio alicantino: Monnegre y Petrer. En general, las tasas de erosión y escorrentía son muy elevadas, lo que se debe al rápido encharcamiento y la inmediata formación de la escorrentía superficial con la lluvia. La zona de Monnegre presenta menores pérdidas de agua, suelo y solutos que la de Petrer, aunque las diferencias dentro de cada zona son mayores que entre ellas. La inexistencia de cubierta vegetal y fragmen- tos de roca da lugar a altas tasas de escorrentía (54% y concentración de sedimentos que oscilan entre 20 y 82 g l -1 , por lo que las tasas de erosión son muy altas (1,5 Kg m 2 h -1 . La pendiente es el factor más importante de las tasas de erosión en los badlands, a lo que hay que sumar el control químico de los procesos de erosión.

  19. PROCEDIMIENTO PARA LA MEJORA DE LOS PROCESOS OPERATIVOS. ETECSA

    Directory of Open Access Journals (Sweden)

    Ileana G. Pérez Vergara

    2009-02-01

    Full Text Available

    El trabajo presenta el diseño de un procedimiento para la mejora de los procesos operativos y su implementación en la Unidad de Negocios Red de la Empresa de Telecomunicaciones de Cuba S.A (UNR. 

    En el mismo se realiza una caracterización de la UNR, se identifica como responsable al proceso “Servicio de Reparación de Tecnologías”, se realiza una evaluación de la calidad al proceso, teniendo en cuenta los requisitos de la Norma ISO 9001/2000, y se muestran los resultados cualitativos y cuantitativos.

    El procedimiento constituye una referencia para la toma de acciones de mejoras que contribuyan a fortalecer el Sistema de Gestión de la Calidad de la UNR.

  20. The effect of gastric inhibitory polypeptide on intestinal glucose absorption and intestinal motility in mice

    Energy Technology Data Exchange (ETDEWEB)

    Ogawa, Eiichi [Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University (Japan); Hosokawa, Masaya [Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University (Japan); Faculty of Human Sciences, Tezukayama Gakuin University, Osaka (Japan); Harada, Norio; Yamane, Shunsuke; Hamasaki, Akihiro; Toyoda, Kentaro; Fujimoto, Shimpei; Fujita, Yoshihito; Fukuda, Kazuhito [Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University (Japan); Tsukiyama, Katsushi; Yamada, Yuichiro [Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University (Japan); Department of Internal Medicine, Division of Endocrinology, Diabetes and Geriatric Medicine, Akita University School of Medicine, Akita (Japan); Seino, Yutaka [Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University (Japan); Kansai Electric Power Hospital, Osaka (Japan); Inagaki, Nobuya, E-mail: inagaki@metab.kuhp.kyoto-u.ac.jp [Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University (Japan); CREST of Japan Science and Technology Cooperation (JST), Kyoto (Japan)

    2011-01-07

    Research highlights: {yields} Exogenous GIP inhibits intestinal motility through a somatostatin-mediated pathway. {yields} Exogenous GIP inhibits intestinal glucose absorption by reducing intestinal motility. {yields} The GIP-receptor-mediated action in intestine does not involve in GLP-1-mediated pathway. -- Abstract: Gastric inhibitory polypeptide (GIP) is released from the small intestine upon meal ingestion and increases insulin secretion from pancreatic {beta} cells. Although the GIP receptor is known to be expressed in small intestine, the effects of GIP in small intestine are not fully understood. This study was designed to clarify the effect of GIP on intestinal glucose absorption and intestinal motility. Intestinal glucose absorption in vivo was measured by single-pass perfusion method. Incorporation of [{sup 14}C]-glucose into everted jejunal rings in vitro was used to evaluate the effect of GIP on sodium-glucose co-transporter (SGLT). Motility of small intestine was measured by intestinal transit after oral administration of a non-absorbed marker. Intraperitoneal administration of GIP inhibited glucose absorption in wild-type mice in a concentration-dependent manner, showing maximum decrease at the dosage of 50 nmol/kg body weight. In glucagon-like-peptide-1 (GLP-1) receptor-deficient mice, GIP inhibited glucose absorption as in wild-type mice. In vitro examination of [{sup 14}C]-glucose uptake revealed that 100 nM GIP did not change SGLT-dependent glucose uptake in wild-type mice. After intraperitoneal administration of GIP (50 nmol/kg body weight), small intestinal transit was inhibited to 40% in both wild-type and GLP-1 receptor-deficient mice. Furthermore, a somatostatin receptor antagonist, cyclosomatostatin, reduced the inhibitory effect of GIP on both intestinal transit and glucose absorption in wild-type mice. These results demonstrate that exogenous GIP inhibits intestinal glucose absorption by reducing intestinal motility through a somatostatin

  1. The effect of gastric inhibitory polypeptide on intestinal glucose absorption and intestinal motility in mice

    International Nuclear Information System (INIS)

    Ogawa, Eiichi; Hosokawa, Masaya; Harada, Norio; Yamane, Shunsuke; Hamasaki, Akihiro; Toyoda, Kentaro; Fujimoto, Shimpei; Fujita, Yoshihito; Fukuda, Kazuhito; Tsukiyama, Katsushi; Yamada, Yuichiro; Seino, Yutaka; Inagaki, Nobuya

    2011-01-01

    Research highlights: → Exogenous GIP inhibits intestinal motility through a somatostatin-mediated pathway. → Exogenous GIP inhibits intestinal glucose absorption by reducing intestinal motility. → The GIP-receptor-mediated action in intestine does not involve in GLP-1-mediated pathway. -- Abstract: Gastric inhibitory polypeptide (GIP) is released from the small intestine upon meal ingestion and increases insulin secretion from pancreatic β cells. Although the GIP receptor is known to be expressed in small intestine, the effects of GIP in small intestine are not fully understood. This study was designed to clarify the effect of GIP on intestinal glucose absorption and intestinal motility. Intestinal glucose absorption in vivo was measured by single-pass perfusion method. Incorporation of [ 14 C]-glucose into everted jejunal rings in vitro was used to evaluate the effect of GIP on sodium-glucose co-transporter (SGLT). Motility of small intestine was measured by intestinal transit after oral administration of a non-absorbed marker. Intraperitoneal administration of GIP inhibited glucose absorption in wild-type mice in a concentration-dependent manner, showing maximum decrease at the dosage of 50 nmol/kg body weight. In glucagon-like-peptide-1 (GLP-1) receptor-deficient mice, GIP inhibited glucose absorption as in wild-type mice. In vitro examination of [ 14 C]-glucose uptake revealed that 100 nM GIP did not change SGLT-dependent glucose uptake in wild-type mice. After intraperitoneal administration of GIP (50 nmol/kg body weight), small intestinal transit was inhibited to 40% in both wild-type and GLP-1 receptor-deficient mice. Furthermore, a somatostatin receptor antagonist, cyclosomatostatin, reduced the inhibitory effect of GIP on both intestinal transit and glucose absorption in wild-type mice. These results demonstrate that exogenous GIP inhibits intestinal glucose absorption by reducing intestinal motility through a somatostatin-mediated pathway rather

  2. Update on small intestinal stem cells.

    Science.gov (United States)

    Tesori, Valentina; Puglisi, Maria Ausiliatrice; Lattanzi, Wanda; Gasbarrini, Giovanni Battista; Gasbarrini, Antonio

    2013-08-07

    Among somatic stem cells, those residing in the intestine represent a fascinating and poorly explored research field. Particularly, somatic stem cells reside in the small intestine at the level of the crypt base, in a constant balance between self-renewal and differentiation. Aim of the present review is to delve into the mechanisms that regulate the delicate equilibrium through which intestinal stem cells orchestrate intestinal architecture. To this aim, special focus will be addressed to identify the integrating signals from the surrounding niche, supporting a model whereby distinct cell populations facilitate homeostatic vs injury-induced regeneration.

  3. Impaired neutrophil function in intestinal lymphangiectasia.

    OpenAIRE

    Bolton, R P; Cotter, K L; Losowsky, M S

    1986-01-01

    Impaired neutrophil chemotaxis and phagocytosis were shown in three patients with intestinal lymphangiectasia. Abnormalities in cell associated and serum derived activity occurred, and possible mechanisms are suggested.

  4. Lymphangiectasia of small intestine presenting as intussusception

    Directory of Open Access Journals (Sweden)

    Katoch Pervez

    2008-07-01

    Full Text Available Intussusception is defined as telescoping of a segment of gastrointestinal tract into an adjacent one. In small children, it is the commonest cause of intestinal obstruction. More than 90% of childhood intussusceptions are idiopathic. We report a rare case of localized small intestinal lymphangiectasia, presenting as intussusception in a 6-month-old male child. The child presented with features of acute intestinal obstruction for which he was later operated. The gross examination of excised ileocecal mass revealed intussusception. Histopathologic examination revealed lymphangiectasia of small intestine, which acted as a lead point for ileocecal intussusception. Postoperative period was uneventful.

  5. Lymphangiectasia of small intestine presenting as intussusception.

    Science.gov (United States)

    Katoch, Pervez; Bhardwaj, Subhash

    2008-01-01

    Intussusception is defined as telescoping of a segment of gastrointestinal tract into an adjacent one. In small children, it is the commonest cause of intestinal obstruction. More than 90% of childhood intussusceptions are idiopathic. We report a rare case of localized small intestinal lymphangiectasia, presenting as intussusception in a 6-month-old male child. The child presented with features of acute intestinal obstruction for which he was later operated. The gross examination of excised ileocecal mass revealed intussusception. Histopathologic examination revealed lymphangiectasia of small intestine, which acted as a lead point for ileocecal intussusception. Postoperative period was uneventful.

  6. Bile acids in regulation of intestinal physiology.

    LENUS (Irish Health Repository)

    Keating, Niamh

    2009-10-01

    In addition to their roles in facilitating lipid digestion and absorption, bile acids are recognized as important regulators of intestinal function. Exposure to bile acids can dramatically influence intestinal transport and barrier properties; in recent years, they have also become appreciated as important factors in regulating cell growth and survival. Indeed, few cells reside within the intestinal mucosa that are not altered to some degree by exposure to bile acids. The past decade saw great advances in the knowledge of how bile acids exert their actions at the cellular and molecular levels. In this review, we summarize the current understanding of the role of bile acids in regulation of intestinal physiology.

  7. SISTEMA SCADA PARA EL PROCESO DE PASTEURIZACION DE JUGOS

    Directory of Open Access Journals (Sweden)

    Juan de Dios Contreras Cáceres

    2014-06-01

    Full Text Available La finalidad de este artículo es dar a conocer el proyecto desarrollado para diseñar e implementar un sistema SCADA (Supervisory Control And Data Adquisition aplicado al proceso de pasteurización de jugos. Se siguieron las etapas de diseño, partiendo de la elaboración del esquemático Layout, la programación del PLC, los drivers de comunicación y el diseño del software SCADA para una planta de jugos.

  8. La proyección como proceso y como mecanismo

    OpenAIRE

    Brusset, Bernard

    2001-01-01

    La proyección es a la vez un mecanismo elemental testimonio de la fragilidad de la organización defensiva y un proceso cuyo rol es fundamental en el funcionamiento psíquico. En este doble aspecto, la proyección guarda especificidades diferentes en la neurosis y en la psicosis al punto que se las deba considerar como fundamentalmente diferentes? O bien las diferencias de contexto, del nivel del funcionamiento psíquico, de lugar, de función pueden explicar las diferencias clínicas justificando ...

  9. Afrontar el proceso de duelo To deal with grief

    OpenAIRE

    Mª Trinidad Pérez Vallejo

    2008-01-01

    Ana, con su testimonio y con su vida nos enseña como afrontar los procesos de duelo. La muerte de su esposo se produce en febrero de 2005, este suceso fue probablemente la experiencia más difícil e importante que ha pasado durante sus 74 años de vida. Ana cuidó a su esposo durante la enfermedad con celo, dedicación y sobre todo con mucho amor. Ahora nos cuenta su experiencia para que pueda servir a aliviar a todas aquellas personas que se hallan en una situación semejante, a la vez, que rinde...

  10. El proceso electoral de 2006 y las reformas electorales necesarias

    OpenAIRE

    Cárdenas, Jaime

    2007-01-01

    En este artículo se abordan los principales acontecimientos del proceso electoral de 2006 y algunos previos como la integración del actual Consejo General del Instituto Federal Electoral. El autor considera que la elección del 2 de julio de 2006 debió anularse por que no cumplió con los principios constitucionales de libertad y autenticidad. También señala que las autoridades electorales de México, incluyendo al Tribunal Electoral del Poder Judicial de la Federación, no estuvieron a la altura...

  11. LA SALUD EN EL PROCESO DE DESCENTRALIZACION TERRITORIAL EN VENEZUELA

    Directory of Open Access Journals (Sweden)

    Maritza Avila Urdaneta

    2001-07-01

    Full Text Available La estrategia de la descentralización del Estado se inicia con la aprobación de la Ley de Descentralización, Delimitación y Transferencia de Competencias del Poder Público (LOD en diciembre de 1989. El propósito de la descentralización es aumentar la capacidad de respuesta eficiente del sistema de servicios a los problemas de salud a la población entre los diferentes niveles de poder central, estadal y municipal, así como brindarle una mayor participación a las comunidades en su solución. En Venezuela las instituciones que prestan servicios de salud son numerosas, en su mayoría independientes y ausentes de una coordinación efectiva por parte del Ministerio de Sanidad y Asistencia Social (MSAS, ente creado en 1936 con mayor injerencia en los asuntos relativos a la salud. El MSAS se orienta hacia una política de centralización normativa – procedimental y desconcentración programática que consiste en la transferencia de las funciones administrativas, requeridas para el desarrollo de los programas, a los órganos regionales del Sistema Nacional de Salud. Destaca que el MSAS delimitará a las comunidades territorial, demográfica y técnicamente, en función del establecimiento de atención integral a la salud que le preste sus servicios. Este trabajo tiene como objetivo evaluar el proceso de descentralización de la salud, tomando en cuenta la actual coyuntura sociopolítica y económica en el marco de la nueva Constitución Bolivariana (1999. La muestra está constituida por los Estados Monagas, Carabobo, Aragua, Falcón y Zulia. Los resultados se concretan en el aumento de la productividad y calidad de los servicios de atención médica; simplificación de los procesos administrativos y el fortalecimiento de la democracia, al contar con una comunidad involucrada y satisfecha con el servicio de salud. Se concluye que el proceso de descentralización municipal ha sido frenado por el Gobierno central en los Estados Monagas y

  12. Las modificaciones estructurales como parte del proceso concursal

    OpenAIRE

    Giron Beckles, Jessica

    2013-01-01

    La investigación propuesta se centra en el estudio de las modificaciones estructurales de sociedades, reguladas por la Ley 3/2009 de 3 de abril, dentro del proceso concursal y tiene como propósito el realizar una labor de hermenéutica jurídica con el fin de sentar las bases para la armonización del Derecho de Sociedades y el Derecho concursal en torno al problema planteado. Busca sistematizar y dar solución a las preguntas que surgen cuando confluyen estas dos regulaciones, mediante el anális...

  13. Escenificar la presencia: O. Welles y F. Kafka, El Proceso

    Directory of Open Access Journals (Sweden)

    González de Ávila, Manuel

    2011-04-01

    Full Text Available Semiotics of presence has changed the ways semiotics considers art works and culture documents. This paper explores its possibilities and limits through an analysis of the O. Welles’ film The Trial, based on the novel by F. Kafka.La semiótica de la presencia ha cambiado el modo en el que la teoría del sentido considera las obras de arte y los documentos de cultura. Este artículo explora sus posibilidades y límites a partir del análisis del filme de O. Welles El proceso, adaptado de la novela homónima de F. Kafka.

  14. Escenificar la presencia: O. Welles y F. Kafka, El Proceso

    OpenAIRE

    González de Ávila, Manuel

    2011-01-01

    Semiotics of presence has changed the ways semiotics considers art works and culture documents. This paper explores its possibilities and limits through an analysis of the O. Welles’ film The Trial, based on the novel by F. Kafka.La semiótica de la presencia ha cambiado el modo en el que la teoría del sentido considera las obras de arte y los documentos de cultura. Este artículo explora sus posibilidades y límites a partir del análisis del filme de O. Welles El proceso, adaptado de la novela ...

  15. Gramsci y el proceso hegemónico educativo

    Directory of Open Access Journals (Sweden)

    Guillermo Miranda-Camacho

    2006-06-01

    Full Text Available El presente ensayo es una aproximación hermenéutica a uno de los núcleos centrales del pensamiento de Antonio Gramsci: la construcción del proceso hegemónico educativo y se destacan la actualidad y vigencia de su pensamiento. Para realizar esta tarea de analizar sus aportaciones, en un primer momento se hace una exploración de la interrelación del concepto de sociedad civil y su interacción dialéctica con el Estado (sociedad política. En un segundo momento se exploran las complejas, poderosas y sutiles formas que asume la hegemonía política y cultural promovida por la clase dirigente, desde el Estado, para consolidar un consenso ideológico en torno a su proyecto hegemónico. En un tercer momento, se exploran algunas dimensiones relativas a la participación directa del Estado en la educación, desde la perspectiva de los procesos que explican la vinculación histórica de lo político y lo educativo. Para comprender este proceso, se retoma el planteamiento gramsciano relativo a la hegemonía que se instaura en la sociedad civil en el marco de la construcción de una unidad social-cultural, analizando el concepto de intelectual orgánico y su papel en la configuración de la hegemonía social. La cuarta parte comprende un análisis de la vinculación histórica Estado-educación, desde la óptica de la articulación orgánica entre la base estructural y la superestructura ideológica, y, por ende, de la construcción de un sistema ideológico. Finalmente, se realiza una aproximación a la visión gramsciana de la vinculación educación-hegemonía, se destaca su significación y su vigencia para el análisis del papel de la política educativa como proceso hegemónico en la sociedad civil.

  16. Las TIC, el proceso del conocimiento y las competencias docentes

    Directory of Open Access Journals (Sweden)

    Augusto Perez Lindo

    2014-11-01

    Full Text Available En el marco del Seminario Internacional "Formación y conocimiento" organizado por la Universidad de Sorocaba presentamos un análisis de los efectos de las TICs en los procesos del conocimiento. Tratamos de demostrar que esos efectos se producen en varias direcciones: cambios en la visión de la realidad, de la subjetividad, del lenguaje, de los paradigmas, de las relaciones sociales. Propone fortalecer competencias adecuadas al cambio de paradigma, como la capacidad para seleccionar e interpretar informaciones, la capacidad para pensar científicamente, la capacidad para comunicar, la capacidad para convivir, la capacidad para dominar varios lenguajes.

  17. Procesos inflamatorios y tratamiento nutricional específico

    OpenAIRE

    López Parra, Andrea

    2014-01-01

    RESUMEN: INTRODUCCIÓN: La inflamación es una respuesta normal del organismo ante ciertos estímulos. Sin embargo, si esta es excesiva o inadecuada, puede dar lugar a distintas patologías. Para el tratamiento y prevención de estas, tanto desde el punto de vista médico como fisioterapéutico, es importante tener una visión holística del problema. En este punto el soporte nutricional es de gran importancia OBJETIVOS: Relacionar la nutrición con los procesos inflamatorios que se llevan a cabo en...

  18. Intestinal Microbiota Signatures Associated With Histological Liver Steatosis in Pediatric-Onset Intestinal Failure

    NARCIS (Netherlands)

    Korpela, K.; Mutanen, A.; Salonen, A.; Savilahti, E.; Vos, de W.M.; Pakarinen, M.P.

    2017-01-01

    BACKGROUND: Intestinal failure (IF)-associated liver disease (IFALD) is the major cause of mortality in IF. The link between intestinal microbiota and IFALD is unclear. METHODS: We compared intestinal microbiota of patients with IF (n = 23) with healthy controls (n = 58) using culture-independent

  19. Intestinal Lymphangiectasia Secondary to Neuroblastoma

    Directory of Open Access Journals (Sweden)

    RM Reifen

    1994-01-01

    Full Text Available An eight month-old infant presented with a 10-day history of vomiting and diarrhea, and a one-week history of swelling of the lower extremities. Laboratory evaluations revealed hypoproteinemia and lymphocytopenia due to protein-losing enteropathy. Peroral small bowel biopsy showed intestinal lymphangiectasia. Subsequent onset of unexplained ecchymosis and obstructive jaundice resulted in additional studies which revealed an omental neuroblastoma as the underlying etiology of the infant’s symptoms. This report emphasizes the importance of considering secondary, obstructive causes for lymphangiectasia and protein-losing enteropathy.

  20. Intestinal subepithelial myofibroblasts support in vitro and in vivo growth of human small intestinal epithelium.

    Directory of Open Access Journals (Sweden)

    Nicholas Lahar

    Full Text Available The intestinal crypt-niche interaction is thought to be essential to the function, maintenance, and proliferation of progenitor stem cells found at the bases of intestinal crypts. These stem cells are constantly renewing the intestinal epithelium by sending differentiated cells from the base of the crypts of Lieberkühn to the villus tips where they slough off into the intestinal lumen. The intestinal niche consists of various cell types, extracellular matrix, and growth factors and surrounds the intestinal progenitor cells. There have recently been advances in the understanding of the interactions that regulate the behavior of the intestinal epithelium and there is great interest in methods for isolating and expanding viable intestinal epithelium. However, there is no method to maintain primary human small intestinal epithelium in culture over a prolonged period of time. Similarly no method has been published that describes isolation and support of human intestinal epithelium in an in vivo model. We describe a technique to isolate and maintain human small intestinal epithelium in vitro from surgical specimens. We also describe a novel method to maintain human intestinal epithelium subcutaneously in a mouse model for a prolonged period of time. Our methods require various growth factors and the intimate interaction between intestinal sub-epithelial myofibroblasts (ISEMFs and the intestinal epithelial cells to support the epithelial in vitro and in vivo growth. Absence of these myofibroblasts precluded successful maintenance of epithelial cell formation and proliferation beyond just a few days, even in the presence of supportive growth factors. We believe that the methods described here can be used to explore the molecular basis of human intestinal stem cell support, maintenance, and growth.

  1. La acreditacion como proceso dinamizador hacia la calidad

    Directory of Open Access Journals (Sweden)

    Belén Boville Luca de Tena

    2006-01-01

    Full Text Available Con metodología de estudio de caso se aborda la acreditación de un centro de Educación Superior mexicano, la Unidad Académica Multidisciplinaria de Comercio y Administración Victoria de la Universidad Autónoma de Tamaulipas. Mediante el estudio del proceso de evaluación se trata de descubrir cómo ha generado el dinamismo que permite una mejora sustancial de la calidad. Los hallazgos ponen de manifiesto un modelo de gestión que privilegia liderazgo compartido, planeación estratégica, autoevaluación y trabajo en equipo en torno a una visión común. Se identifica una planta docente profesionalizada y programas de estudio con enfoque integral, complementado con actividades de investigación, cultura y deporte. Comprometidos con un proceso de mejora contínua, la consolidación de metas a corto y largo plazo está íntimamente relacionada con el sentido de pertenencia de sus miembros a esa organización. La corresponsabilidad ante el éxito o el fracaso es una característica clave en el éxito de esta comunidad educativa.

  2. La muerte como proceso: una perspectiva antropológica

    Directory of Open Access Journals (Sweden)

    Bárbara Martínez

    2013-09-01

    Full Text Available Este artículo, desde una perspectiva antropológica, combina recientes aproximaciones que cuestionan la homología entre muerte y deceso biológico, con la tradición de estudios que revisan los rituales de muerte en el área geográfica andina. En particular, examina cómo se produce en El Cajón, Catamarca, noroeste argentino, la incorporación de un fallecido al esquema cosmológico, y cómo la muerte, que es un puntapié inicial para ello ocurra, no es meramente un evento biológico sino también un proceso social de gran dinamismo. A partir del trabajo de campo etnográfico, y tomando como herramientas metodológicas entrevistas abiertas de sesiones múltiples y observación participante, presenta una propuesta analítica que procura superar la homología entre muerte y deceso biológico, sugiriendo una noción que incluye la dimensión orgánica, pero también la social: el proceso de la muerte.

  3. El desarrollo de la marcha infantil como proceso de aprendizaje

    Directory of Open Access Journals (Sweden)

    Patricia Martín Casas

    2014-06-01

    Full Text Available El desarrollo de la marcha infantil es un proceso especialmente complejo en que el intervienen factores motores, perceptivos y cognitivos. Desde el nacimiento, el niño integra la información recibida y realiza un progresivo control cortical sobre los patrones neuromotores innatos para desarrollar diferentes formas de locomoción hasta la marcha independiente. Estas ideas no son novedosas pero se están revisando en la actualidad y han motivado numerosos cambios en el estudio del desarrollo infantil. La consideración de la adquisición de la marcha como un aprendizaje en situaciones de constante cambio permite comprender la marcha como acción, cuya realización implica la adquisición de nuevas capacidades de interacción y conocimientos. En este trabajo se exponen los principales conocimientos acerca de este proceso de aprendizaje y se propone destacar las alteraciones de la marcha como indicadores de dificultades en el desarrollo, que requieren una valoración y un abordaje terapéutico interdisciplinares.

  4. Neuropsicología del proceso creativo. Un enfoque educativo

    Directory of Open Access Journals (Sweden)

    Verónica López-Fernández

    2018-01-01

    Full Text Available Vivimos en un contexto y en una sociedad en constante cambio, que requiere que las personas se adapten a las nuevas circunstancias en las que nos hallamos. La creatividad es uno de los elementos más importantes a tener en cuenta como facilitador de la adaptación. Por todo ello, es de especial relevancia su estudio desde todas las perspectivas científicas. Por este motivo, el objetivo del presente estudio es aportar un mejor entendimiento de la creatividad desde un enfoque neuropsicológico, dado el carácter multidimensional del constructo. Se ha llevado a cabo una revisión de algunas investigaciones que estudian la creatividad desde la neurociencia y se propone una visión de las funciones neuropsicológicas implicadas en dicho proceso, en función de la fase en la que nos encontramos ante actividades creativas y que fueron establecidas por Wallas (1926: preparación, incubación, iluminación y verificación. Los resultados muestran que hay funciones cognitivas de especial relevancia en cada una de las fases y estructuras cerebrales con gran activación en las distintas etapas del proceso creativo. Por último, se propone con esta nueva perspectiva del estudio de la creatividad, un punto de partida para realizar otras investigaciones.

  5. Proceso experiencial: comprendiendo al ser humano en primera persona

    Directory of Open Access Journals (Sweden)

    Alberto De Castro

    2012-01-01

    Full Text Available Este es un artículo de revisión y reflexión teórica acerca de los fundamentos psicológicos del proceso experiencial de los seres humanos. Este artículo nació de la necesidad de situar en primera persona la participación y postura psicológica que los seres humanos asumen en la vida cotidiana a partir de los significados, valores e intenciones que tratan de afirmar ante las distintas experiencias, situaciones y determinismos que enfrentan. A partir de la revisión de distintos autores contemporáneos, de conclusiones basadas en experiencia clínica y de los resultados de distintas investigaciones fenomenológicas hermenéuticas, se concluye que el proceso experiencial implica y está caracterizado por la interrelación entre los conceptos de deseo, voluntad, sentido, valoración, consciencia e intencionalidad.

  6. Las superestructuras textuales en los procesos pedagógicos

    Directory of Open Access Journals (Sweden)

    Pardo Abril Neyla Graciela

    1992-06-01

    Full Text Available

    El propósito de este documento es presentar e ilustrar algunas consideraciones tendientes a posibilitar una metodología que se acerque de manera más funcional al desarrollo integral de las habilidades comunicativas, a partir de un marco teórico que aproxime a la descripción, explicación y predicción de los procesos de la producción y comprensión discursiva, teniendo en cuenta las más importantes contribuciones que en este sentido han elaborado la lingüística de texto, la sicología cognoscitiva y la cibernética, en particular, las digresiones en torno a la inteligencia artificial, desde donde se señala la importancia que tienen los procesos y categorías cognoscitivas en la comprensión y producción de discursos.

  7. Prematurity reduces functional adaptation to intestinal resection in piglets

    DEFF Research Database (Denmark)

    Aunsholt, Lise; Thymann, Thomas; Qvist, Niels

    2015-01-01

    Background: Necrotizing enterocolitis and congenital gastrointestinal malformations in infants often require intestinal resection, with a subsequent risk of short bowel syndrome (SBS). We hypothesized that immediate intestinal adaptation following resection of the distal intestine with placement ...

  8. Bioactive Milk for Intestinal Maturation in Preterm Neonates

    DEFF Research Database (Denmark)

    Li, Yanqi

    The fetal small intestine grows dramatically fast during the second and third trimester of human pregnancy. Many intestinal functions are therefore affected by preterm birth, including gastrointestinal motility, digestive and absorptive function, mucosal barrier function, and the intestinal...

  9. Redistribution of intestinal microcirculatory oxygenation during acute hemodilution in pigs

    NARCIS (Netherlands)

    Schwarte, Lothar A.; Fournell, Artur; van Bommel, Jasper; Ince, Can

    2005-01-01

    Acute normovolemic hemodilution (ANH) compromizes intestinal microcirculatory oxygenation; however, the underlying mechanisms are incompletely understood. We hypothesized that contributors herein include redistribution of oxygen away from the intestines and shunting of oxygen within the intestines.

  10. Intestinal

    International Nuclear Information System (INIS)

    Cardenas, Rene; Haro, Elfa

    2002-01-01

    The paper present the diagnosic sensitivit of gastro esophagic scintigraphy (GCE) in children with suspiction of gastro esophagic reflux (RGE), as well as to evidence bronchial aspiratin in cases with suspected RGE. There was studied two groups of children: group A: Include 73 childs with documented diagnosis of RGE, by meas of cine esophagography. Group B: Include 22 children with symptoms of suspiction of. (The author)

  11. Propuesta para evaluar la capacidad de procesos de manufactura multivariados

    Directory of Open Access Journals (Sweden)

    Manuel Alberto Rodriguez Medina

    2014-08-01

    Full Text Available Los productos manufacturados hoy en día poseen varias características de calidad que son importantes para el cliente y cuando no están correlacionadas, se usan varios índices de capacidad, tales como el Cp, Cpk y Cpm para evaluar la habilidad que tiene el proceso de producir productos de calidad. Para el caso contrario, se encontró en la revisión de literatura, índices de capacidad propuestos para medir la capacidad de un proceso cuando las características de calidad están correlacionadas. La mayoría de las propuestas coinciden en que debe definirse una región de especificación que represente lo que el cliente desea y otra región de variación del proceso que muestre el desempeño que tiene el proceso. Adicionalmente, como resultados de la revisión anterior, se observa que los autores difieren en la forma de definir ambas regiones, oportunidad que se aprovecha para presentar una nueva propuesta, mediante la cual se definen de una manera confiable ambas regiones y que al compararlas se obtienen un par de índices de capacidad multivariados CpM y CpkM, que son extensiones de los índices univariados Cp y Cpk. Por último, se utilizan los datos de un proceso, los cuales se pueden modelar por medio de una distribución normal bivariada para calcular los índices de capacidad propuestos en este trabajo, posteriormente se comparan con el valor de otros índices de capacidad similares, propuestos por otros autores, obteniéndose un desempeño por sobre otros índices de la literatura consultada. The manufactured products have several quality characteristics that are important for the customer. When the quality characteristics are not correlated, using several indices, such as Cp, Cpk and Cpm to assess the ability of the process to produce quality products. For the opposite case was found in the literature review, proposed capability indices to measure the ability of a process when the quality characteristics are correlated. Most proposals

  12. Arquitectura constitucional y procesos de integración en el caso portugués

    OpenAIRE

    Noronha Rodrigues, José

    2008-01-01

    Con medio siglo de la existencia, el proceso europeo de integración/Unión Europea se encuentra, actualmente, en una encrucijada nueva. Sin embargo, hoy nos parece incuestionable que la integración europea es un proceso irreversible. Portugal, por la vía de las revisiones constitucionales sucesivas, ha conseguido acompasar y adaptar su arquitectura constitucional al proceso europeo de la integración.

  13. Lymphoma Caused by Intestinal Microbiota

    Directory of Open Access Journals (Sweden)

    Mitsuko L. Yamamoto

    2014-09-01

    Full Text Available The intestinal microbiota and gut immune system must constantly communicate to maintain a balance between tolerance and activation: on the one hand, our immune system should protect us from pathogenic microbes and on the other hand, most of the millions of microbes in and on our body are innocuous symbionts and some can even be beneficial. Since there is such a close interaction between the immune system and the intestinal microbiota, it is not surprising that some lymphomas such as mucosal-associated lymphoid tissue (MALT lymphoma have been shown to be caused by the presence of certain bacteria. Animal models played an important role in establishing causation and mechanism of bacteria-induced MALT lymphoma. In this review we discuss different ways that animal models have been applied to establish a link between the gut microbiota and lymphoma and how animal models have helped to elucidate mechanisms of microbiota-induced lymphoma. While there are not a plethora of studies demonstrating a connection between microbiota and lymphoma development, we believe that animal models are a system which can be exploited in the future to enhance our understanding of causation and improve prognosis and treatment of lymphoma.

  14. Chronic intestinal pseudo-obstruction.

    Science.gov (United States)

    Gabbard, Scott L; Lacy, Brian E

    2013-06-01

    Chronic intestinal pseudo-obstruction (CIP) is a rare and serious disorder of the gastrointestinal (GI) tract characterized as a motility disorder with the primary defect of impaired peristalsis; symptoms are consistent with a bowel obstruction, although mechanical obstruction cannot be identified. CIP is classified as a neuropathy, myopathy, or mesenchymopathy; it is a neuropathic process in the majority of patients. The natural history of CIP is generally that of a progressive disorder, although occasional patients with secondary CIP note significant symptomatic improvement when the underlying disorder is identified and treated. Symptoms vary from patient to patient depending on the location of the luminal GI tract involved and the degree of involvement; however, the small intestine is nearly always involved. Common symptoms include dysphagia, gastroesophageal reflux, abdominal pain, nausea, vomiting, bloating, abdominal distension, constipation or diarrhea, and involuntary weight loss. Unfortunately, these symptoms are nonspecific, which can contribute to misdiagnosis or a delay in diagnosis and treatment. Since many of the symptoms and signs suggest a mechanical bowel obstruction, diagnostic tests typically focus on uncovering a mechanical obstruction, although routine tests do not identify an obstructive process. Nutrition supplementation is required for many patients with CIP due to symptoms of dysphagia, nausea, vomiting, and weight loss. This review discusses the epidemiology, etiology, pathogenesis, diagnosis, and treatment of patients with CIP, with an emphasis on nutrition assessment and treatment options for patients with nutrition compromise.

  15. Is nonoperative management of adhesive intestinal obstruction ...

    African Journals Online (AJOL)

    Background: Nonoperative management of adhesive intestinal obstruction gives good results in adults but there are scant studies on its outcome in children. This study reports outcomes and experiences with nonoperative and operative management of adhesive intestinal obstruction in children in a resource-poor country.

  16. A CLINICAL STUDY OF ADHESIVE INTESTINAL OBSTRUCTION

    OpenAIRE

    Haricharan; Murali Krishna; Koti Reddy; Nara Hari

    2015-01-01

    INTRODUCTION: Adhesive intestinal obstruction is an inevitable complication of abdominal surgeries. It has high morbidity with associated poor quality of life and predisposition to repeated hospitalization. Commonest cause of bowel obstruction in developed countries is postoperative adhesions with extrinsic compression of the intestine. Most of them can be managed conservatively. METHODS: A retrospective study of 30 patients admit...

  17. Intestinal lymphangiectasia mimicking primary peritoneal carcinoma.

    Science.gov (United States)

    Steines, Jennifer C; Larson, Joshua H; Wilkinson, Neal; Kirby, Patricia; Goodheart, Michael J

    2010-10-01

    Intestinal lymphangiectasia is an obstruction of the lymphatic system. We report on a patient with mesenteric adenopathy and an elevated CA125 level, which were suspicious for peritoneal carcinoma. Further evaluation and bowel resection identified intestinal lymphangiectasia. This disease should be considered in patients with mesenteric adenopathy and a small bowel mass. Copyright © 2010 Mosby, Inc. All rights reserved.

  18. Intestinal cholesterol secretion: future clinical implications

    NARCIS (Netherlands)

    Jakulj, L.; Besseling, J.; Stroes, E. S. G.; Groen, A. K.

    2013-01-01

    Together with the liver, the intestine serves as a homeostatic organ in cholesterol metabolism. Recent evidence has substantiated the pivotal role of the intestine in reverse cholesterol transport (RCT). RCT is a fundamental antiatherogenic pathway, mediating the removal of cholesterol from tissues

  19. Intestinal cholesterol secretion : future clinical implications

    NARCIS (Netherlands)

    Jakulj, L.; Besseling, J.; Stroes, E. S. G.; Groen, A. K.

    2013-01-01

    Together with the liver, the intestine serves as a homeostatic organ in cholesterol metabolism. Recent evidence has substantiated the pivotal role of the intestine in reverse cholesterol transport (RCT). RCT is a fundamental antiatherogenic pathway, mediating the removal of cholesterol from tissues

  20. Radiodiagnosis of diseases of the small intestine

    International Nuclear Information System (INIS)

    Anon.

    1987-01-01

    Roentgenological image of diseases, development anomalies, various diseases of the small intestine is presented. Roentgenological semiotics of chronic enterocolotis, absorption failure syndrome, Crohn's disease, tuberculosis, abdominal actinomycosis, carcenoid, benign tumors, small intestine cancer, is given. To state final correct diagnosis a complex investigation, comprising angiography, computer tomography and ultrasound diagnosis, is necessary

  1. Ruminal and Intestinal Digestibility of Leucaena Foliage

    African Journals Online (AJOL)

    pramote

    2013-12-30

    Dec 30, 2013 ... Keywords: Intestinal digestibility, protein fodder, mobile nylon bag, a three-step technique ... A potential strategy for increasing the quality and availability of feed for small ruminants in the dry ... to measure intestinal disappearance of DM and CP using the mobile bag method described by De Boer et al.

  2. Ectoparasites and intestinal helminths of speckled pigeon ...

    African Journals Online (AJOL)

    Ectoparasites and intestinal helminths of speckled pigeon ( Columba guinea Hartlaub and Finsch 1870) in Zaria, Nigeria. ... Science World Journal ... A total of 30 (20 males and 10 females) Speckled Pigeons trapped from the wild in Zaria and its environs, Nigeria, were examined for ectoparasites and intestinal helminths, ...

  3. Laparoscopic Treatment of Intestinal Malrotation in Children

    NARCIS (Netherlands)

    Ooms, N.; Matthyssens, L.E.; Draaisma, J.M.T.; Blaauw, I. de; Wijnen, M.H.

    2016-01-01

    Purpose Intestinal malrotation is a congenital intestinal rotation anomaly, which can be treated by either laparotomy or laparoscopy. Our hypothesis is that laparoscopic treatment leads to less small bowel obstruction because of the fewer adhesions in comparison to laparotomy, without increasing the

  4. Monozygotic twins with discordant intestinal rotation

    International Nuclear Information System (INIS)

    Smith, Vance L.; Nwomeh, Benedict C.; Long, Frederick

    2006-01-01

    Previous case reports have suggested a strong concordance of intestinal malrotation among identical twins. This has led to the recommendation that the asymptomatic twin undergo screening when malrotation is discovered in the identical sibling. We present a case of monozygotic twins in which one twin presented with intestinal malrotation with midgut volvulus while the other twin was found to have normal gastrointestinal anatomy. (orig.)

  5. Monozygotic twins with discordant intestinal rotation

    Energy Technology Data Exchange (ETDEWEB)

    Smith, Vance L.; Nwomeh, Benedict C. [Ohio State University College of Medicine and Public Health, Department of Pediatric Surgery, Columbus Children' s Hospital, Columbus, OH (United States); Long, Frederick [Ohio State University College of Medicine and Public Health, Department of Radiology, Columbus Children' s Hospital, Columbus, OH (United States)

    2006-04-15

    Previous case reports have suggested a strong concordance of intestinal malrotation among identical twins. This has led to the recommendation that the asymptomatic twin undergo screening when malrotation is discovered in the identical sibling. We present a case of monozygotic twins in which one twin presented with intestinal malrotation with midgut volvulus while the other twin was found to have normal gastrointestinal anatomy. (orig.)

  6. Intestinal malrotation and volvulus in adult life

    NARCIS (Netherlands)

    Haak, Bastiaan W.; Bodewitz, Sander T.; Kuijper, Caroline F.; de Widt-Levert, Louise M.

    2014-01-01

    Midgut volvulus due to intestinal malrotation is a rare cause of intestinal obstruction when occurring in adult life. This paper documents the difficulties in reaching an early diagnosis. We describe the case of an 85-year-old man with non-specific abdominal complaints for 20 years, who presented

  7. Un framework para el despliegue y evaluación de procesos software

    OpenAIRE

    Ruiz-Rube, Iván

    2014-01-01

    La Ingeniería de Procesos Software promueve la producción sistemática de software mediante el seguimiento de una serie de procesos bien definidos. Una gestión integral de dichos procesos implica el desarrollo de una serie de actividades como son el diseño de los modelos de procesos, la verificación, la validación, el despliegue y la posterior evaluación. El consorcio OMG publicó el estándar Software Process Engineering Metamodel (SPEM), un lenguaje destinado a facilitar y potenciar el entendi...

  8. Regional specialization within the intestinal immune system

    DEFF Research Database (Denmark)

    Mowat, Allan M.; Agace, William Winston

    2014-01-01

    The intestine represents the largest compartment of the immune system. It is continually exposed to antigens and immunomodulatory agents from the diet and the commensal microbiota, and it is the port of entry for many clinically important pathogens. Intestinal immune processes are also increasingly...... implicated in controlling disease development elsewhere in the body. In this Review, we detail the anatomical and physiological distinctions that are observed in the small and large intestines, and we suggest how these may account for the diversity in the immune apparatus that is seen throughout...... the intestine. We describe how the distribution of innate, adaptive and innate-like immune cells varies in different segments of the intestine and discuss the environmental factors that may influence this. Finally, we consider the implications of regional immune specialization for inflammatory disease...

  9. Multispectral tissue characterization for intestinal anastomosis optimization

    Science.gov (United States)

    Cha, Jaepyeong; Shademan, Azad; Le, Hanh N. D.; Decker, Ryan; Kim, Peter C. W.; Kang, Jin U.; Krieger, Axel

    2015-10-01

    Intestinal anastomosis is a surgical procedure that restores bowel continuity after surgical resection to treat intestinal malignancy, inflammation, or obstruction. Despite the routine nature of intestinal anastomosis procedures, the rate of complications is high. Standard visual inspection cannot distinguish the tissue subsurface and small changes in spectral characteristics of the tissue, so existing tissue anastomosis techniques that rely on human vision to guide suturing could lead to problems such as bleeding and leakage from suturing sites. We present a proof-of-concept study using a portable multispectral imaging (MSI) platform for tissue characterization and preoperative surgical planning in intestinal anastomosis. The platform is composed of a fiber ring light-guided MSI system coupled with polarizers and image analysis software. The system is tested on ex vivo porcine intestine tissue, and we demonstrate the feasibility of identifying optimal regions for suture placement.

  10. ACUTE INTESTINAL INFECTIONS: THERAPEUTICAL TACTICS IN CHILDREN

    Directory of Open Access Journals (Sweden)

    A.N. Surkov

    2011-01-01

    Full Text Available Acute intestinal infections are quite common among children. Their clinical presentations include intoxication syndrome (drowsiness, low appetite, fever etc, infectious toxic syndrome (toxicosis with exicosis, neurotoxicosi, hypovolemic or infectious-toxic shockand diarrhea syndrome. Sometimes intestinal infections can be quite severe and even lethal. However disease duration and outcome depend on timelines and adequacy of prescribed treatment. Main guidelines of intestinal infections treatment include probiotics. That is why the right choice of probiotics is important for a pediatrician. The article contains basic information upon etiopathogenesis, classification, diagnostic criteria and acute pediatric intestinal infections treatment guidelines.Key words: acute intestinal infections, etiopathogenesis, diagnostic criteria, treatment, probiotics, children. (Voprosy sovremennoi pediatrii — Current Pediatrics. — 2011; 10 (6: 141–147

  11. EL PROFESOR COMO GESTOR DEL PROCESO ACADÉMICO

    Directory of Open Access Journals (Sweden)

    María Morella Colls Carrillo

    2013-03-01

    Full Text Available El presente estudio tiene como objetivo abordar los procesos de cambio que están ocurriendo en la educación superior, y el papel del profesor universitario como gestor del conocimiento en entorno del aprendizaje. En tal sentido, se analizan y discuten las percepciones de un grupo de profesores de la Universidad Nacional Experimental Simón Rodríguez en torno de las tecnologías de la información y de la comunicación (TICs y los cambios que genera su implementación en los procesos de enseñanza y del aprendizaje. El escenario es los cambios que se generan con la implementación de las tecnologías de la información y de la comunicación en los procesos de enseñanza aprendizaje. El resultado de esta investigación se traducirá en las interpretaciones conceptuales y teóricas que darán soporte a la conceptualización conforme a la nueva visión expresada en el marco legal que la fundamenta y en su pertinencia social. Como aporte se espera generar constructos teóricos sobre la actuación del profesor como gestor universitario.PALABRAS CLAVE: conocimiento; educación; comunicación; TICsTHE TEACHER AS AGENT OF THE ACADEMIC PROCESS  ABSTRACTThe present study has as objective to approach the processes of change that are happening in the superior education, and the university professor's paper as agent of the knowledge in environment of the learning. In such a sense, they are analyzed and the perceptions of a group of professors of the National Experimental University name after Simón Rodríguez in lathe of the information and of the communication technologies (ICT and the changes that generates their implementation in the teaching and learning processes. The scenario is the changes that are generated with the implementation of the technologies of the information and of the communication in the processes of teaching learning. The result of this investigation will be translated in the conceptual and theoretical interpretations that will give

  12. Aspectos institucionales del proceso latinoamericano de integración

    Directory of Open Access Journals (Sweden)

    Felipe Herrera

    2014-09-01

    Full Text Available La formación de un espacio económico que abarque los territorios de varios Estados requiere de dos elementos esenciales: la voluntad política de los países de participar en un proceso de integración de sus economías y la existencia de instrumentos jurídicos e institucionales adecuados para traducir las decisiones políticas en programas concretos de acción oportuna y coordinadamente ejecutados. El estudio de los aspectos institucionales de la integración latinoamericana ha adquirido especial importancia a partir de las decisiones adoptadas en abril de 1967 en Punta del Este por los presidentes latinoamericanos, en el sentido de crear un mercado común regional a partir de 1970. La necesidad de contar con instrumentos institucionales adecuados para llevar a la práctica las decisiones presidenciales confronta a los países con la necesidad de analizar profundamente los instrumentos que ahora existen a fin de perfeccionarlos y adaptarlos a las tareas propias de una comunidad económica. Este análisis debe basarse en un planteamiento muy claro de tipo institucional que -aprovechando la experiencia acumulada a través de la integración económica europea y prestando la debida consideración a las características que reviste este proceso en el caso de América Latina- contemple y defina el rol que están llamados a desempeñar en la promoción de este proceso los gobiernos y las administraciones de los países participantes, las instituciones creadas especialmente por los instrumentos jurídicos de la integración y los organismos internacionales especializados que colaboran en el desarrollo de la región. Este texto apareció por primera vez en Osvaldo Sunkel (Comp. Integración Política y Económica (pp. 311-344, Santiago de Chile, Editorial Universitaria, 1970.

  13. LA MERCADOTECNIA MUSICAL EN EL PROCESO DE APRENDIZAJE DE UNIVERSITARIOS

    Directory of Open Access Journals (Sweden)

    Eduardo Muñoz Bautista

    2017-10-01

    Full Text Available Una de las instituciones educativas nivel superior más representativas de este estado es la (UAEH la misma que sostiene ser la institución de enseñanza más antigua de esta entidad federativa. El plantel nació con el estado; en sus distintas etapas de desarrollo se reflejan las correspondientes épocas de la historia hidalguense. Así mismo establece que durante 48 años de vida institucional, la Universidad ha vivido múltiples e importantes cambios caracterizados por un rápido crecimiento y expansión de cada una de sus funciones sustantivas. El presente artículo presenta los resultados de la investigación Perspectiva de aceptación del Marketing musical en una Universidad El Caso: Universidad Autónoma del Estado de Hidalgo (UAEH Instituto de Ciencias Económico Administrativas (ICEA, encontrándose como antecedentes que las instituciones de educación superior tienen como objetivo formar competencias en los individuos de acuerdo a su área del conocimiento, de tal forma que desarrolle armónicamente las facultades cognitivas, afectivas y psicomotoras, a fin de propiciar continuamente su mejoramiento intelectual, físico, social, moral y cultural. El diseño de la investigación fue de corte cuantitativo, transversal, descriptivo y Correlacional, teniendo como Hipótesis: H1: Los alumnos tienen una Actitud positiva hacia la conducta al emplear marketing musical dentro del proceso enseñanza-aprendizaje. H2: Los alumnos tienen creencias subjetivas de manera positiva aplicables al marketing musical dentro del proceso enseñanza-aprendizaje. De acuerdo a los resultados obtenidos el notable la aceptación de reproducción de música por parte del estudiante dentro su formación académica sin embargo, la mayoría señala que no se les ha dado la oportunidad de incorporar la música dentro de sus actividades académicas así como en su proceso de aprendizaje dentro de su escuela, por tanto se propone a los directivos de la instituci

  14. [Neovagina with intestine: 13 cases].

    Science.gov (United States)

    Parente, A; Molina, E; Cerdá, J; Cañizo, A; Rodriguez, A; Laín, A; Fanjul, M; Vázquez, J

    2008-01-01

    The absence or hipoplasia vaginal can turn out to be isolated, associated with ambiguous genitalia, or as anatomical variant in a syndrome of sewer. The fundamental aim in the creation of a new vagina is: to obtain a good aesthetic result, to fulfil functional criteria (elasticity, sensibility, physiological inclination) and to improve the quality of life of the patients avoiding the use of molds and minimizing the morbidity of the zones donors. In this work let's sense beforehand our experience in the accomplishment of neovaginas with intestine. We analyze the clinical record of 13 patients treated surgically in the last ten years. We differentiate two groups according to the age, the diagnosis and the type of surgery: a) the first group of 8 patients present syndrome of insensibility to the androgens (4), syndrome of Rokitansky (2), extrofia of sewer (1) and mixed gonadal disgenesia (1). This group of patients were controlled in the adolescence by an average of age of 19 years (11-35 years), they fulfilling a neovagina with sigma; b) the second group of 5 patients with sewer (3), extrofia of sewer (1) and congenital suprarrenal hiperplasia (1). This group was controlled prematurely by a middle ages of one year (4 months-3 years). The intestinal segment used as neovagina was sigma (2), ileon (2) and rectum (1), and was performed during the surgical correction of her congenital malformation. Two patients have presented intestinal obstruction in the postoperatory immediate one. Four patients have needed removal of a small vaginal prolapse, and three have needed vaginal transitory expansions for introit stenosis. The long-term evolution has been favorable with an excellent aesthetic aspect. Four patients recount sexual fully satisfactory relations. We believe that the neovagina with sigma is at present the best option in patients with absence or hipoplasia vaginal. The advantages are the possibility of precocious and one time correction, a neovagina of dimensions and

  15. El proceso turístico : sujetos, agentes y efectos

    Directory of Open Access Journals (Sweden)

    Eva Martín Roda

    2001-06-01

    Full Text Available Desde el marco teórico, el artículo analiza las motivaciones que inducen al hombre a efectuar un viaje. El tipo de agentes, tanto públicos como privados, que influyen en el proceso turístico como sus motivaciones y los efectos que el turismo tiene sobre ámbitos sociales y económicos.Starting from a theoretical approach, this anide analyses what are the drivers that decide people to take a trip, either business or holidays trips. Going further to identify what are the public or prívate agents that influence the tourism process and the broad impact that the tourism has on social and economic framework.

  16. Conceptualización del proceso de envejecimiento

    Directory of Open Access Journals (Sweden)

    María Guadalupe Zetina Lozano

    1999-01-01

    Full Text Available El estudio de las personas mayores requiere de la conceptualización a la que se han referido diversas disciplinas, independientemente de los diversos enfoques teóricos que cada una sostiene. Se realiza en este trabajo una revisión de las principales tesis utilizadas por las disciplinas demográfica, biológica, socioeconómica, sociocultural y psicológica, principalmente enfocada al desarrollo humano. De estos planteamientos teóricos surgen supuestos hipotéticos: las personas de la tercera edad deben ubicarse dentro de un proceso dinámico, por lo que se propone estudiarlas en sus diferentes edades. Los resultados también dependen directamente de la forma en que se haya vivido esas etapas. Para ser analizado integralmente este fenómeno, será observado a través de dimensiones interdisciplinarias y del entorno familiar.

  17. Proceso creativo y ready-made en la publicidad

    Directory of Open Access Journals (Sweden)

    João Anzanello Carrascoza

    2012-04-01

    Full Text Available La creación publicitaria es el resultado de una práctica de bricolaje llevada a cabo por un redactor y un director de arte – profesionales que actúan a dúo en las agencias de publicidad y que son los responsables de la elaboración de los mensajes publicitarios. En este proceso, estos profesionales echan mano de todo tipo de materiales culturales para crear las piezas que les son solicitadas. Ambos se valen sistemáticamente, como materia prima, de citaciones de imágenes y enunciados fundadores, interfiriendo en su significado, hecho que hace pensar en los ready-mades de Duchamp. Este artículo aporta una reflexión sobre el ready-made como método de creación en la publicidad y sus implicaciones en el mundo de los signos.

  18. El rendimiento diferido del proceso didáctico

    Directory of Open Access Journals (Sweden)

    Juan Bautista CODINA BAS

    2009-11-01

    Full Text Available El análisis input-output es un modelo de investigación utilizado en las ciencias económicas y que se viene aplicando en el campo didáctico con diversos objetivos; bien de carácter político-administrativo para ayudar a tomar decisiones adecuadas, bien con el deseo de optimizar el proceso didáctico, buscando la calidad y eficacia en la educación. En todos los estudios se trata de identificar cuáles son los pesos de los factores que influyen en el rendimiento de los estudiantes, o dicho de otra forma: ¿hasta qué punto las variaciones en los rendimientos son explicados por la variación en los recursos utilizados? En resumen, se trata de conocer si el resultado obtenido está en consonancia con los medios adoptados.

  19. PROCESO DE FORMACIÓN URBANA DE ORIHUELA (ALICANTE

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    Gregorio Canales Martínez

    1992-01-01

    Full Text Available La evolución urbana de Orihuela ha venido marcada por un progresivo desplaza- miento desde su primitiva ubicación de carácter defensivo en el Monte San Miguel hasta ir ocupando las tierras ribereñas del río Segura, cuyo cauce ha definido hasta fechas muy cercanas su desarrollo urbano. El estudio determina los elementos y circunstancias que han condicionado el proceso de formación urbana desde el siglo XIV hasta nuestros días y sus tendencias expansivas, a través del análisis de la documentación histórica disponi- ble, tanto gráfica como bibliográfica, ofreciendo así una síntesis de la evolución histórica de la ciudad.

  20. Desarrollo de Simuladores para Procesos Industriales. Parte III (Colada continua

    Directory of Open Access Journals (Sweden)

    Ramírez, A.

    2006-06-01

    Full Text Available This work was written for illustrating the use of Monte Carlo methods and generating of random number in combination with the information of the simulation system for thermal behavior described previously in order to reproduce in a computer the solidification process of the steel and simulate the formation of structures of casting step by step.

    Este trabajo muestra el empleo de técnicas de métodos de Monte Carlo y generación de números aleatorios en combinación con datos obtenidos del sistema de simulación (SSCC para comportamiento térmico previamente descrito para la reproducción computacional del proceso de solidificación del acero y simular la formación de estructuras de colada paso a paso.

  1. Laparoscopic intestinal derotation: original technique.

    Science.gov (United States)

    Valle, Mario; Federici, Orietta; Tarantino, Enrico; Corona, Francesco; Garofalo, Alfredo

    2009-06-01

    The intestinal derotation technique, introduced by Cattel and Valdoni 40 years ago, is carried out using a laparoscopic procedure, which is described here for the first time. The method is effective in the treatment of malign lesions of the III and IV duodenum and during laparoscopic subtotal colectomy with anastomosis between the ascending colon and the rectum. Ultimately, the procedure allows for the verticalization of the duodenal C and the anterior positioning of the mesenteric vessels, facilitating biopsy and resection of the III and IV duodenal portions and allowing anastomosis of the ascending rectum, avoiding both subtotal colectomy and the risk of torsion of the right colic loop. Although the procedure calls for extensive experience with advanced video-laparoscopic surgery, it is both feasible and repeatable. In our experience we have observed no mortality or morbidity.

  2. Tres experimentos Modernos. El proceso de proyecto del edificio Positano

    Directory of Open Access Journals (Sweden)

    Juan Pablo Tuja

    2017-04-01

    Full Text Available El edificio Positano, proyectado durante la década de 1950 por el arquitecto Luis García Pardo, marca un hito en la arquitectura de la vivienda colectiva moderna en el Uruguay. Para concretar este edificio, el arquitecto -y promotor inmobiliario a la vez- desarrolló una serie de proyectos, identificándose tres proyectos completamente documentados. Esta serie posee un fuerte carácter moderno y experimental, el cual se expresa en la volumetría general, la implantación, en el desarrollo tipológico, el diseño estructural y el diseño de los cerramiento exteriores. El último proyecto, realizado en asociación con el joven arquitecto Adolfo Sommer Smith, comienza a construirse en 1959. La serie de proyectos, evidencia un creciente proceso de “abstracción”, tanto formal como conceptual. Lo cual conducirá por un lado a simplificar formas y reducir elementos, y por otro a diseñar dispositivos de mayor complejidad, capaces de resolver funciones diversas al mismo tiempo. A partir de la búsqueda y clasificación de documentación de época –planos, fotografías, artículos, entre otros–, el presente trabajo intentó ensayar una interpretación proyectual, exponiendo las principales preocupaciones y estrategias de los arquitectos. El ensayo buscó reconocer repeticiones, iteraciones, dudas y certezas de un proceso proyectual intenso, que transitó los bordes de la disciplina.

  3. Alteraciones psicosociales en el proceso docente-educativo

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    Patricia María Herrera Santí

    2001-08-01

    Full Text Available Resumen Nuestra investigación estudió algunos de los factores psicosociales por los que está influido el proceso docente-educativo y las alteraciones de aprendizaje y conducta en educandos de enseñanza primaria. Conocimos sexo y edades más frecuentes en las que se afecta el proceso docente-educativo, establecimos relación entre el estilo de participación del niño y las alteraciones docentes, constatamos la influencia de crisis familiares no transitorias y el funcionamiento familiar, evaluamos igualmente el funcionamiento intelectual y las principales áreas de conflicto. Se encontró un predominio de los trastornos de conducta sobre los trastornos del aprendizaje, un funcionamiento intelectual dentro de límites normales, así como también una adecuada maduración neuromotriz; una alta incidencia de crisis familiares no transitorias, alteraciones en el clima familiar y un mal funcionamiento familiar.Summary We studied some of the psychosocial factors influencing on the teaching-educative process and the learning and behavioral alterations in primary school students. We knew the most frequent age and sex in which the teaching-educative process is affected, we established a relationship between the style of participation of the child and the teaching alterations, and evaluated the intellectual functioning and the main conflict areas. It was observed a predominance of the behavorial disorders over the learning disorders, an intellectual functioning within the normal limits, as well as an adequate neuromotor maturation, a high incidence of non-transitory family crises, alteration in the family atmosphere and a poor family functioning.

  4. ACCESIBILIDAD AL PROCESO EDUCATIVO EN EL ENTORNO UNIVERSITARIO

    Directory of Open Access Journals (Sweden)

    Martha Gross Martínez

    2016-01-01

    Full Text Available Resumen: Este artículo presenta los hallazgos de la investigación Accesibilidad en la permanencia de estudiantes con necesidades educativas asociadas o no a discapacidad, en una universidad pública de Costa Rica (2012-2014. El objetivo de dicho estudio consistió en analizar la accesibilidad desde la percepción estudiantil sobre las acciones, apoyos y servicios dentro de la vida universitaria, a partir de las diferentes dimensiones de la accesibilidad (espacio físico, información y proceso educativo y con ello aportar propuestas que permitan y dinamicen la inclusión en este nivel educativo. Este estudio se adscribe a la investigación cualitativa. La población participante se seleccionó considerando las necesidades de accesibilidad en el entorno universitario. Se expone de manera particular el análisis de los resultados sobre accesibilidad al proceso educativo en este contexto. Se realizó una revisión bibliográfica que permitiera la reflexión sobre el objeto de estudio, además, se llevó a cabo una encuesta en línea al estudiantado y la realización de grupos focales para la recolección de datos. Finalmente, se pone de manifiesto los logros y carencias que existen en materia de accesibilidad en el ámbito educativo, puntualizando aspectos vinculantes con el derecho a la educación y el compromiso institucional, ante los desafíos que esta población enfrenta en el quehacer de la vida estudiantil.

  5. El Proceso de Internacionalización de Empresas

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    Arnoldo Araya Leandro

    2013-01-01

    Full Text Available El fenómeno de la globalización insta a las empresas adesarrollar estrategias con el propósito de internacionalizarse,no obstante es una tarea compleja. En algunos casos, loque busca la internacionalización es la apertura de nuevosmercados, en otros es que los costos de producción sean másbajos y que haya una estructura eficiente de producción ydistribución. Dado lo anterior, el proceso de internacionalizaciónempresarial debe responder las siguientes preguntas:¿por qué se internacionaliza la empresa?, ¿cuál es el procesopara llevarlo a cabo?, ¿cómo se internacionaliza? y ¿dóndepuede localizar sus actividades en el exterior? (Galán, Galende,González, 2000. A partir de estos cuestionamientosla presente investigación bibliográfica tiene como objetivoprincipal mostrar el proceso que deben seguir las empresascon el fin de internacionalizarse.   ABSTRACT The globalization phenomenon pressures companies intothe complex undertaking of the development of strategies fortheir internationalization. Sometimes internationalizationseeks opening new markets, in other cases its goals are loweringproduction and distribution costs. As a result, any companyseeking to participate in an internationalization process mustanswer the following questions: Why do we want to go global?What’s the process that must be followed?How do you do it? Where are we going to operate? (Galan,Galende, Gonzalez, 2000. From these questions the currentliterature research shows the procedure to be followed bycompanies wishing to operate worldwide.

  6. Empoderamiento: Proceso, Nivel y Contexto Empowerment: Process, Level, and Context

    Directory of Open Access Journals (Sweden)

    Carmen Silva

    2004-11-01

    Full Text Available En este artículo se discute el fenómeno del empoderamiento y se analiza la distinción teórica entre proceso y resultado de empoderamiento (Zimmerman, 2000. A partir de las formulaciones de este autor y el aporte de una perspectiva interaccional (Bronfenbrenner, 1987, se sostiene que aquella diferenciación es poco viable en términos objetivos y absolutos o de esencia, pero sí útil, en términos analíticos, desde la percepción de la propia comunidad involucrada, que debe ser comprendida por el colaborador externo. También se propone establecer una diferencia entre contexto y nivel de empoderamiento, y analizar el contexto del fenómeno en los niveles individual, organizacional y comunitario del agregado social, lo que aporta claridad a su definición. De esta manera adquiere centralidad la concepción del empoderamiento como proceso en sucesivos contextos que benefician no sólo a los individuos sino que a los colectivos socialesA critical analysis of the concept of empowerment and the theoretical distinction between empowerment process and outcome (Zimmerman, 2000 are presented. Based on Zimmerman's conceptualisation, and the interaccional perspective (Bronfenbrenner, 1987, we argue that the distinction between empowerment process and outcome, though analytically useful (if based on the perception of the community itself from their own experience, which must be understood by professional agent is not always viable in absolute or objective terms. In addition, we suggest to distinguish between context and level of analyses in empowerment theory, and to analyze the context of the empowerment phenomenon at the individual, organizational and community level, which clarifies the definition of each of them. In sum, empowerment is conceived as a process within successive contexts that benefits not only individuals, but also different social aggregate kinds of groups

  7. Diffused and sustained inhibitory effects of intestinal electrical stimulation on intestinal motility mediated via sympathetic pathway.

    Science.gov (United States)

    Zhao, Xiaotuan; Yin, Jieyun; Wang, Lijie; Chen, Jiande D Z

    2014-06-01

    The aims were to investigate the energy-dose response effect of intestinal electrical stimulation (IES) on small bowel motility, to compare the effect of forward and backward IES, and to explore the possibility of using intermittent IES and mechanism of IES on intestinal motility. Five dogs implanted with a duodenal cannula and one pair of intestinal serosal electrodes were studied in five sessions: 1) energy-dose response study; 2) forward IES; 3) backward IES; 4) intermittent IES vs. continuous IES; 5) administration of guanethidine. The contractile activity and tonic pressure of the small intestine were recorded. The duration of sustained effect after turning off IES was manually calculated. 1) IES with long pulse energy dose dependently inhibited contractile activity and tonic pressure of the small intestine (p intestine depended on the energy of IES delivered (p intestine. 5) Guanethidine blocked the inhibitory effect of IES on intestinal motility. IES with long pulses inhibits small intestinal motility; the effect is energy-dose dependent, diffused, and sustained. Intermittent IES has the same efficacy as the continuous IES in inhibiting small intestinal motility. Forward and backward IES have similar inhibitory effects on small bowel motility. This IES-induced inhibitory effect is mediated via the sympathetic pathway. © 2013 International Neuromodulation Society.

  8. La disputa por la homologación de los procesos electorales en Chiapas

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    Álvaro F. López Lara

    2008-06-01

    Full Text Available En este trabajo se analizan las decisiones y estrategias de los actores políticos en torno al proceso de reforma para homologar el calendario electoral en Chiapas. Este caso muestra que aunque las reformas para homologar los procesos son deseables, su realización moviliza ambiciones de los poderes locales e incrementan las tensiones institucionales.

  9. El proceso de incapacitación en los casos de enfermedad mental

    OpenAIRE

    Gómez López, Samanta

    2012-01-01

    El proceso de incapacitación es un proceso legal con una fuerte base psicológica y es un concepto que se puede abordar desde las dos perspectivas. Este trabajo expone el estudio de los diferentes trastornos psicológicos que pueden influir para incapacitar a un sujeto.

  10. Congenital intestinal lymphangiectasia. A case report

    Directory of Open Access Journals (Sweden)

    Georgios Mitsiakos

    2017-12-01

    Full Text Available Congenital intestinal lymphangiectasia, first described by Waldmann et al. in 1961, is a rare congenital malformation of the lymphatics, presented with generalized edema, hypoproteinemia and lymphopenia. Diagnosis is based on endoscopy findings and pathology.We present here a case of a male neonate, second child of an indigenous woman, delivered by caesarean section. Prenatally, multiple cystic abdominal masses were identified by ultrasound. The patient was treated successfully with enterectomy and anastomosis. Histopathology revealed primary intestinal lymphangiectasia with no features of malignancy.Intestinal lymphangiectasia is a rare pathology, which should be differentiated while exploring abdominal masses, hypoproteinemia and edema especially in neonates.

  11. Intestinal Leiomyositis: A Cause of Chronic Intestinal Pseudo?Obstruction in 6 Dogs

    OpenAIRE

    Zacuto, A.C.; Pesavento, P.A.; Hill, S.; McAlister, A.; Rosenthal, K.; Cherbinsky, O.; Marks, S.L.

    2015-01-01

    Background Intestinal leiomyositis is a suspected autoimmune disorder affecting the muscularis propria layer of the gastrointestinal tract and is a cause of chronic intestinal pseudo?obstruction in humans and animals. Objective To characterize the clinical presentation, histopathologic features, and outcome of dogs with intestinal leiomyositis in an effort to optimize treatment and prognosis. Animals Six client?owned dogs. Methods Retrospective case series. Medical records were reviewed to de...

  12. Interactions between the intestinal microbiota and innate lymphoid cells

    Science.gov (United States)

    Chen, Vincent L; Kasper, Dennis L

    2014-01-01

    The mammalian intestine must manage to contain 100 trillion intestinal bacteria without inducing inappropriate immune responses to these microorganisms. The effects of the immune system on intestinal microorganisms are numerous and well-characterized, and recent research has determined that the microbiota influences the intestinal immune system as well. In this review, we first discuss the intestinal immune system and its role in containing and maintaining tolerance to commensal organisms. We next introduce a category of immune cells, the innate lymphoid cells, and describe their classification and function in intestinal immunology. Finally, we discuss the effects of the intestinal microbiota on innate lymphoid cells. PMID:24418741

  13. Experiencing sexuality after intestinal stoma

    Directory of Open Access Journals (Sweden)

    Maria Angela Boccara de Paula

    2012-06-01

    Full Text Available OBJECTIVE: Identify the Social Representations (SR of ostomized people in terms of sexuality after the stoma. METHODS: An exploratory, descriptive, qualitative study using the Social Representation Theory with 15 ostomized people (8 females, mean age of 57.9 years, between August and September 2005. Data obtained from transcribed interviews were submitted to content analysis, resulting in the thematic unit "Giving new meaning to sexuality" and subthemes. RESULTS: The study demonstrated that the intestinal stoma interferes in the sexuality experience, showing that the meanings attributed to this experience are based on individual life stories, quality of personal relationships established in practice and perception of sexuality, despite the stoma. CONCLUSIONS: The Social Representations, in terms of experiencing sexuality after the stoma, are based on meanings attributed to the body, associated with daily life and present in the social imaginary. It is influenced by other factors, such as physiological changes resulting from the surgery and the fact of having or not a partner. Care taken during sexual practices provide greater security and comfort in moments of intimacy, resembling the closest to what ostomized people experienced before the stoma. The self-irrigation technique associated or not with the use of artificial occluder, has been attested by its users as a positive element that makes a difference in sexual practice after the stoma. The support to ostomized people should be comprehensive, not limited to technical care and disease, which are important, but not sufficient. The interdisciplinary health team should consider all aspects of the person, seeking a real meeting between subjects.OBJETIVO: Identificar as Representações Sociais (RS da pessoa estomizada intestinal sobre vivência da sexualidade após confecção do estoma. MÉTODOS: Estudo exploratório, descritivo, qualitativo do ponto de vista do referencial da Representa

  14. Modelo de aseguramiento de la calidad en el proceso de desarrollo de software basado en los modelos de madurez de capacidades (CMMi), proceso de software para equipos (TSP) y personas (PSP)

    OpenAIRE

    Espejo Chavarría, Alex José

    2016-01-01

    Genera e implementa un modelo de aseguramiento de la calidad en el proceso de desarrollo de software con un enfoque orientado al factor humano; factor que es responsable de introducir y gestionar la calidad en el proceso de desarrollo de software. El modelo propuesto se basa en tres modelos “Modelos de Madurez de Capacidades Integrado, Proceso de Software para Equipos y Proceso de Software para Personas. Tesis

  15. Intestinal Iron Homeostasis and Colon Tumorigenesis

    Directory of Open Access Journals (Sweden)

    Yatrik M. Shah

    2013-06-01

    Full Text Available Colorectal cancer (CRC is the third most common cause of cancer-related deaths in industrialized countries. Understanding the mechanisms of growth and progression of CRC is essential to improve treatment. Iron is an essential nutrient for cell growth. Iron overload caused by hereditary mutations or excess dietary iron uptake has been identified as a risk factor for CRC. Intestinal iron is tightly controlled by iron transporters that are responsible for iron uptake, distribution, and export. Dysregulation of intestinal iron transporters are observed in CRC and lead to iron accumulation in tumors. Intratumoral iron results in oxidative stress, lipid peroxidation, protein modification and DNA damage with consequent promotion of oncogene activation. In addition, excess iron in intestinal tumors may lead to increase in tumor-elicited inflammation and tumor growth. Limiting intratumoral iron through specifically chelating excess intestinal iron or modulating activities of iron transporter may be an attractive therapeutic target for CRC.

  16. Diversity and functions of intestinal mononuclear phagocytes

    DEFF Research Database (Denmark)

    Joeris, Thorsten; Müller-Luda, K; Agace, William Winston

    2017-01-01

    The intestinal lamina propria (LP) contains a diverse array of mononuclear phagocyte (MNP) subsets, including conventional dendritic cells (cDC), monocytes and tissue-resident macrophages (mφ) that collectively play an essential role in mucosal homeostasis, infection and inflammation. In the curr......The intestinal lamina propria (LP) contains a diverse array of mononuclear phagocyte (MNP) subsets, including conventional dendritic cells (cDC), monocytes and tissue-resident macrophages (mφ) that collectively play an essential role in mucosal homeostasis, infection and inflammation....... In the current review we discuss the function of intestinal cDC and monocyte-derived MNP, highlighting how these subsets play several non-redundant roles in the regulation of intestinal immune responses. While much remains to be learnt, recent findings also underline how the various populations of MNP adapt...

  17. Pterostilbene Prevents Intestinal Ischemia Reperfusion Injury in ...

    African Journals Online (AJOL)

    Methods: Male Wistar rats were divided into 4 groups as follows: Control group; intestinal .... excitation wavelength (485 nm) and emission wavelength (528 nm). The results ... Ethanolic phase of the tissue homogenate was extracted using ...

  18. Gastro-intestinal phytobezoars in Zimbabwean Africans.

    Science.gov (United States)

    Stein, C M; Gelfand, M

    1985-01-01

    The clinical features of 10 African patients with gastro-intestinal phytobezoars are described. These were similar to those described with persimmon bezoars and we postulate that the fruit of locally found trees, also of the genus Diospyros, are responsible.

  19. Intestinal Colonization Dynamics of Vibrio cholerae.

    Directory of Open Access Journals (Sweden)

    Salvador Almagro-Moreno

    2015-05-01

    Full Text Available To cause the diarrheal disease cholera, Vibrio cholerae must effectively colonize the small intestine. In order to do so, the bacterium needs to successfully travel through the stomach and withstand the presence of agents such as bile and antimicrobial peptides in the intestinal lumen and mucus. The bacterial cells penetrate the viscous mucus layer covering the epithelium and attach and proliferate on its surface. In this review, we discuss recent developments and known aspects of the early stages of V. cholerae intestinal colonization and highlight areas that remain to be fully understood. We propose mechanisms and postulate a model that covers some of the steps that are required in order for the bacterium to efficiently colonize the human host. A deeper understanding of the colonization dynamics of V. cholerae and other intestinal pathogens will provide us with a variety of novel targets and strategies to avoid the diseases caused by these organisms.

  20. Epidemiology of small intestinal atresia in Europe

    DEFF Research Database (Denmark)

    Best, Kate E; Tennant, Peter W G; Addor, Marie-Claude

    2012-01-01

    The epidemiology of congenital small intestinal atresia (SIA) has not been well studied. This study describes the presence of additional anomalies, pregnancy outcomes, total prevalence and association with maternal age in SIA cases in Europe....

  1. Congenital central hypoventilation syndrome and intestinal ...

    African Journals Online (AJOL)

    ... hypoventilation syndrome (CCHS), also called 'Ondine's curse', is characterised by an abnormal ventilatory response to progressive hypercapnia and sustained hypoxaemia. Neonates with this condition experience hypoventilation or apnoea while asleep. Patients may also have congenital intestinal aganglionosis (CIA), ...

  2. Mesenteric lipoma causing recurrent intestinal obstruction

    African Journals Online (AJOL)

    2013-01-12

    Jan 12, 2013 ... vomiting, constipation, and central abdominal mass. ... Mesenteric lipoma may cause abdominal pain by complete intestinal .... Kaniklides C, Frykberg T, Lundkvist K. Pediatric mesenteric lipoma: An unusual cause of repeated ...

  3. Inflammasome in Intestinal Inflammation and Cancer

    Directory of Open Access Journals (Sweden)

    Tiago Nunes

    2013-01-01

    Full Text Available The activation of specific cytosolic pathogen recognition receptors, the nucleotide-binding-oligomerization-domain- (NOD- like receptors (NLRs, leads to the assembly of the inflammasome, a multimeric complex platform that activates caspase-1. The caspase-1 pathway leads to the upregulation of important cytokines from the interleukin (IL-1 family, IL-1β, and IL-18, with subsequent activation of the innate immune response. In this review, we discuss the molecular structure, the mechanisms behind the inflammasome activation, and its possible role in the pathogenesis of inflammatory bowel diseases and intestinal cancer. Here, we show that the available data points towards the importance of the inflammasome in the innate intestinal immune response, being the complex involved in the maintenance of intestinal homeostasis, correct intestinal barrier function and efficient elimination of invading pathogens.

  4. Estudio comparativo de la productividad y calidad obtenidas en la soldadura de tubos de calidad T9 empleados en el sector petroquímico, mediante los procesos TIG, HW-TIG y PAW Comparative study of productivity and quality obtained in tube welding quality T9 employees in the petrochemical industry, through TIG, HW-TIG and PAW processes

    Directory of Open Access Journals (Sweden)

    César García González

    2012-09-01

    Full Text Available Tradicionalmente, la fabricación soldada de tuberías de acero Cr-Mo empleadas en serpentines de hornos para la industria petroquímica se ha venido realizando de forma masiva mediante procesos de baja productividad, principalmente TIG para la pasada de raíz y SMAW para las pasadas de relleno, ambos manuales. En este estudio se muestran los resultados de la investigación realizada por el Centro Tecnológico AIMEN, en relación al empleo de tecnologías de alto rendimiento, concretamente TIG, HW-TIG y PAW robotizadas, aplicadas a los mismos materiales y productos. De este modo se calculan y comparan cuatro índices de productividad: Tiempo de Soldadura, Tasa de Deposición, Material Depositado y Volumen de Gas Consumido. El objetivo del estudio es contribuir a la reducción de los tiempos de producción, de los costes de fabricación, y a la mejora de la calidad del producto.Traditionally, the manufacture of welded Cr-Mo steel pipes used in furnace coils for petrochemical industry has been carried out on a massive scale by low productivity processes, mainly TIG for root pass and SMAW for layers of filling run, both of them manuals. This study presents the results of a research, conducted by AIMEN Technology Centre, related to the use of high performance technologies, specifically robotic processes such as TIG, TIG-HW and PAW, applied to the same materials and products. Thus, four productivity ratios have been calculated and compared: welding time, deposition rate, deposited material and volume of consumed gas. The aim of the study is to contribute to the reduction of the production time, manufacturing costs and to the improvement of the product quality.

  5. Neuroimmune regulation during intestinal development and homeostasis.

    Science.gov (United States)

    Veiga-Fernandes, Henrique; Pachnis, Vassilis

    2017-02-01

    Interactions between the nervous system and immune system are required for organ function and homeostasis. Evidence suggests that enteric neurons and intestinal immune cells share common regulatory mechanisms and can coordinate their responses to developmental challenges and environmental aggressions. These discoveries shed light on the physiology of system interactions and open novel perspectives for therapy designs that target underappreciated neurological-immunological commonalities. Here we highlight findings that address the importance of neuroimmune cell units (NICUs) in intestinal development, homeostasis and disease.

  6. Non-Meckel Small Intestine Diverticulitis

    Directory of Open Access Journals (Sweden)

    Shamim Ejaz

    2017-08-01

    Full Text Available Non-Meckel small intestine diverticulitis can have many manifestations and its management is not well-defined. We report 4 unselect cases of small intestine diverticulitis; all patients were seen by the same physician at the Emergency Center at The University of Texas MD Anderson Cancer Center between 1999 and 2014. The median age at diagnosis of these patients was 82 years (range, 76–87 years. All 4 patients presented with acute onset of abdominal pain, and computed tomography scans showed characteristics of small intestine diverticulitis unrelated to cancer. Most of the diverticula were found in the region of the duodenum and jejuno-ileal segments of the small intestine. The patients, even those with peripancreatic inflammation and localized perforation, were treated conservatively. Non-Meckel diverticulitis can be overlooked in the initial diagnosis because of the location of the diverticulosis, the age of the patient, and the rarity of the disease. Because patients with non-Meckel small intestine diverticulitis can present with acute abdominal pain, non-Meckel small intestine diverticulitis should be considered in the differential diagnosis of patients with acute abdominal pain, and computed tomography scans can help identify the condition. Because of the rarity of non-Meckel small intestine diverticulitis, few studies have been published, and the data are inconclusive about how best to approach these patients. Our experience with these 4 elderly patients indicates that non-Meckel small intestine diverticulitis can be treated conservatively, which avoids the potential morbidity and mortality of a surgical approach.

  7. Spectrum of diseases in acute intestinal obstruction

    International Nuclear Information System (INIS)

    Masud, M.; Khan, A.; Gondal, Z.I.; Adil, M.

    2015-01-01

    To determine the etiological spectrum of acute intestinal obstruction in our clinical setup Military Hospital Rawalpindi. Study Design: Descriptive study. Place and Duration of Study: Surgical department of Military Hospital, Rawalpindi from Jul 2012 to Jul 2013, over a period of about 1 year. Material and Methods: A total of 120 patients with acute mechanical intestinal obstruction who underwent laparotomy were included in our study while those with non-mechanical intestinal obstruction like history of trauma and paralytic ileus were excluded from the study. All the patients were selected by non-probability purposive sampling technique. Emergency laparotomy was done and operative findings were recorded. Results: A total of 120 patients with mechanical intestinal obstruction were included in this study out of which 93 (69.17%) were female and remaining 27 (30.83%) were males. Male to female ratio was 1:2.24. Age range of patients was 22-85 years. Out of 120 patients operated for acute intestinal obstruction post-op adhesions were found in 37 (30.83%) patients followed by intestinal tuberculosis in 23 (19.17%) patients, obstructed inguinal hernias in 13 (10.83%), gut malignancies in 15 (12.5%) , Meckel's diverticulum with bands in 7 (5.83%), volvulus in 7 (5.83%), perforated appendix in 6 (5%), intussusception in 2 (1.7%), inflammatory bands in 5 (4.17%), trichobezoar and faecal impaction in 2 (1.7%) while in 3 (2.5%) patients no definite cause was found. Conclusion: Post-op adhesions are the commonest cause of mechanical intestinal obstruction in our setup followed by intestinal tuberculosis as second most common clinical pattern of presentation. (author)

  8. Intestinal perforation by an ingested foreign body*

    Science.gov (United States)

    Nicolodi, Gabriel Cleve; Trippia, Cesar Rodrigo; Caboclo, Maria Fernanda F. S.; de Castro, Francisco Gomes; Miller, Wagner Peitl; de Lima, Raphael Rodrigues; Tazima, Leandro; Geraldo, Jamylle

    2016-01-01

    Objective To identify the computed tomography findings suggestive of intestinal perforation by an ingested foreign body. Materials and Methods This was a retrospective study of four cases of surgically proven intestinal perforation by a foreign body, comparing the computed tomography findings with those described in the literature. Results None of the patients reported having ingested a foreign body, all were over 60 years of age, three of the four patients used a dental prosthesis, and all of the foreign bodies were elongated and sharp. In all four patients, there were findings indicative of acute abdomen. None of the foreign bodies were identified on conventional X-rays. The computed tomography findings suggestive of perforation were thickening of the intestinal walls (in all four cases), increased density of mesenteric fat (in all four cases), identification of the foreign body passing through the intestinal wall (in three cases), and gas in the peritoneal cavity (in one case). Conclusion In cases of foreign body ingestion, intestinal perforation is more common when the foreign body is elongated and sharp. Although patients typically do not report having ingested such foreign bodies, the scenario should be suspected in elderly individuals who use dental prostheses. A computed tomography scan can detect foreign bodies, locate perforations, and guide treatment. The findings that suggest perforation are thickening of the intestinal walls, increased mesenteric fat density, and, less frequently, gas in the peritoneal cavity, often restricted to the point of perforation. PMID:27818542

  9. Intestinal perforation by an ingested foreign body

    International Nuclear Information System (INIS)

    Nicolodi, Gabriel Cleve; Trippia, Cesar Rodrigo; Caboclo, Maria Fernanda F.S.; Castro, Francisco Gomes de; Miller, Wagner Peitl; Lima, Raphael Rodrigues de; Tazima, Leandro; Geraldo, Jamylle

    2016-01-01

    Objective: To identify the computed tomography findings suggestive of intestinal perforation by an ingested foreign body. Materials and Methods: This was a retrospective study of four cases of surgically proven intestinal perforation by a foreign body, comparing the computed tomography findings with those described in the literature. Results: None of the patients reported having ingested a foreign body, all were over 60 years of age, three of the four patients used a dental prosthesis, and all of the foreign bodies were elongated and sharp. In all four patients, there were findings indicative of acute abdomen. None of the foreign bodies were identified on conventional X-rays. The computed tomography findings suggestive of perforation were thickening of the intestinal walls (in all four cases), increased density of mesenteric fat (in all four cases), identification of the foreign body passing through the intestinal wall (in three cases), and gas in the peritoneal cavity (in one case). Conclusion: In cases of foreign body ingestion, intestinal perforation is more common when the foreign body is elongated and sharp. Although patients typically do not report having ingested such foreign bodies, the scenario should be suspected in elderly individuals who use dental prostheses. A computed tomography scan can detect foreign bodies, locate perforations, and guide treatment. The findings that suggest perforation are thickening of the intestinal walls, increased mesenteric fat density, and, less frequently, gas in the peritoneal cavity, often restricted to the point of perforation. (author)

  10. Intestinal perforation by an ingested foreign body.

    Science.gov (United States)

    Nicolodi, Gabriel Cleve; Trippia, Cesar Rodrigo; Caboclo, Maria Fernanda F S; de Castro, Francisco Gomes; Miller, Wagner Peitl; de Lima, Raphael Rodrigues; Tazima, Leandro; Geraldo, Jamylle

    2016-01-01

    To identify the computed tomography findings suggestive of intestinal perforation by an ingested foreign body. This was a retrospective study of four cases of surgically proven intestinal perforation by a foreign body, comparing the computed tomography findings with those described in the literature. None of the patients reported having ingested a foreign body, all were over 60 years of age, three of the four patients used a dental prosthesis, and all of the foreign bodies were elongated and sharp. In all four patients, there were findings indicative of acute abdomen. None of the foreign bodies were identified on conventional X-rays. The computed tomography findings suggestive of perforation were thickening of the intestinal walls (in all four cases), increased density of mesenteric fat (in all four cases), identification of the foreign body passing through the intestinal wall (in three cases), and gas in the peritoneal cavity (in one case). In cases of foreign body ingestion, intestinal perforation is more common when the foreign body is elongated and sharp. Although patients typically do not report having ingested such foreign bodies, the scenario should be suspected in elderly individuals who use dental prostheses. A computed tomography scan can detect foreign bodies, locate perforations, and guide treatment. The findings that suggest perforation are thickening of the intestinal walls, increased mesenteric fat density, and, less frequently, gas in the peritoneal cavity, often restricted to the point of perforation.

  11. Intestinal perforation by an ingested foreign body

    Energy Technology Data Exchange (ETDEWEB)

    Nicolodi, Gabriel Cleve; Trippia, Cesar Rodrigo; Caboclo, Maria Fernanda F.S.; Castro, Francisco Gomes de; Miller, Wagner Peitl; Lima, Raphael Rodrigues de; Tazima, Leandro; Geraldo, Jamylle, E-mail: gabrielnicolodi@gmail.com [Hospital Sao Vicente - Funef, Curitiba, PR (Brazil)

    2016-09-15

    Objective: To identify the computed tomography findings suggestive of intestinal perforation by an ingested foreign body. Materials and Methods: This was a retrospective study of four cases of surgically proven intestinal perforation by a foreign body, comparing the computed tomography findings with those described in the literature. Results: None of the patients reported having ingested a foreign body, all were over 60 years of age, three of the four patients used a dental prosthesis, and all of the foreign bodies were elongated and sharp. In all four patients, there were findings indicative of acute abdomen. None of the foreign bodies were identified on conventional X-rays. The computed tomography findings suggestive of perforation were thickening of the intestinal walls (in all four cases), increased density of mesenteric fat (in all four cases), identification of the foreign body passing through the intestinal wall (in three cases), and gas in the peritoneal cavity (in one case). Conclusion: In cases of foreign body ingestion, intestinal perforation is more common when the foreign body is elongated and sharp. Although patients typically do not report having ingested such foreign bodies, the scenario should be suspected in elderly individuals who use dental prostheses. A computed tomography scan can detect foreign bodies, locate perforations, and guide treatment. The findings that suggest perforation are thickening of the intestinal walls, increased mesenteric fat density, and, less frequently, gas in the peritoneal cavity, often restricted to the point of perforation. (author)

  12. Cytokine Tuning of Intestinal Epithelial Function

    Directory of Open Access Journals (Sweden)

    Caroline Andrews

    2018-06-01

    Full Text Available The intestine serves as both our largest single barrier to the external environment and the host of more immune cells than any other location in our bodies. Separating these potential combatants is a single layer of dynamic epithelium composed of heterogeneous epithelial subtypes, each uniquely adapted to carry out a subset of the intestine’s diverse functions. In addition to its obvious role in digestion, the intestinal epithelium is responsible for a wide array of critical tasks, including maintaining barrier integrity, preventing invasion by microbial commensals and pathogens, and modulating the intestinal immune system. Communication between these epithelial cells and resident immune cells is crucial for maintaining homeostasis and coordinating appropriate responses to disease and can occur through cell-to-cell contact or by the release or recognition of soluble mediators. The objective of this review is to highlight recent literature illuminating how cytokines and chemokines, both those made by and acting on the intestinal epithelium, orchestrate many of the diverse functions of the intestinal epithelium and its interactions with immune cells in health and disease. Areas of focus include cytokine control of intestinal epithelial proliferation, cell death, and barrier permeability. In addition, the modulation of epithelial-derived cytokines and chemokines by factors such as interactions with stromal and immune cells, pathogen and commensal exposure, and diet will be discussed.

  13. Intestinal perforation by an ingested foreign body

    Directory of Open Access Journals (Sweden)

    Gabriel Cleve Nicolodi

    Full Text Available Abstract Objective: To identify the computed tomography findings suggestive of intestinal perforation by an ingested foreign body. Materials and Methods: This was a retrospective study of four cases of surgically proven intestinal perforation by a foreign body, comparing the computed tomography findings with those described in the literature. Results: None of the patients reported having ingested a foreign body, all were over 60 years of age, three of the four patients used a dental prosthesis, and all of the foreign bodies were elongated and sharp. In all four patients, there were findings indicative of acute abdomen. None of the foreign bodies were identified on conventional X-rays. The computed tomography findings suggestive of perforation were thickening of the intestinal walls (in all four cases, increased density of mesenteric fat (in all four cases, identification of the foreign body passing through the intestinal wall (in three cases, and gas in the peritoneal cavity (in one case. Conclusion: In cases of foreign body ingestion, intestinal perforation is more common when the foreign body is elongated and sharp. Although patients typically do not report having ingested such foreign bodies, the scenario should be suspected in elderly individuals who use dental prostheses. A computed tomography scan can detect foreign bodies, locate perforations, and guide treatment. The findings that suggest perforation are thickening of the intestinal walls, increased mesenteric fat density, and, less frequently, gas in the peritoneal cavity, often restricted to the point of perforation.

  14. Lynch syndrome-related small intestinal adenocarcinomas.

    Science.gov (United States)

    Jun, Sun-Young; Lee, Eui-Jin; Kim, Mi-Ju; Chun, Sung Min; Bae, Young Kyung; Hong, Soon Uk; Choi, Jene; Kim, Joon Mee; Jang, Kee-Taek; Kim, Jung Yeon; Kim, Gwang Il; Jung, Soo Jin; Yoon, Ghilsuk; Hong, Seung-Mo

    2017-03-28

    Lynch syndrome is an autosomal-dominant disorder caused by defective DNA mismatch repair (MMR) genes and is associated with increased risk of malignancies in multiple organs. Small-intestinal adenocarcinomas are common initial manifestations of Lynch syndrome. To define the incidence and characteristics of Lynch syndrome-related small-intestinal adenocarcinomas, meticulous familial and clinical histories were obtained from 195 patients with small-intestinal adenocarcinoma, and MMR protein immunohistochemistry, microsatellite instability, MLH1 methylation, and germline mutational analyses were performed. Lynch syndrome was confirmed in eight patients (4%), all of whom had synchronous/metachronous malignancies without noticeable familial histories. Small-intestinal adenocarcinomas were the first clinical manifestation in 37% (3/8) of Lynch syndrome patients, and second malignancies developed within 5 years in 63% (5/8). The patients with accompanying Lynch syndrome were younger (≤50 years; P=0.04) and more likely to have mucinous adenocarcinomas (P=0.003), and tended to survive longer (P=0.11) than those with sporadic cases. A meticulous patient history taking, MMR protein immunolabeling, and germline MMR gene mutational analysis are important for the diagnosis of Lynch syndrome-related small-intestinal adenocarcinomas. Identifying Lynch syndrome in patients with small-intestinal adenocarcinoma can be beneficial for the early detection and treatment of additional Lynch syndrome-related cancers, especially in patients who are young or have mucinous adenocarcinomas.

  15. Fecal markers of intestinal inflammation and intestinal permeability are elevated in Parkinson's disease.

    Science.gov (United States)

    Schwiertz, Andreas; Spiegel, Jörg; Dillmann, Ulrich; Grundmann, David; Bürmann, Jan; Faßbender, Klaus; Schäfer, Karl-Herbert; Unger, Marcus M

    2018-02-12

    Intestinal inflammation and increased intestinal permeability (both possibly fueled by dysbiosis) have been suggested to be implicated in the multifactorial pathogenesis of Parkinson's disease (PD). The objective of the current study was to investigate whether fecal markers of inflammation and impaired intestinal barrier function corroborate this pathogenic aspect of PD. In a case-control study, we quantitatively analyzed established fecal markers of intestinal inflammation (calprotectin and lactoferrin) and fecal markers of intestinal permeability (alpha-1-antitrypsin and zonulin) in PD patients (n = 34) and controls (n = 28, group-matched for age) by enzyme-linked immunosorbent assay. The study design controlled for potential confounding factors. Calprotectin, a fecal marker of intestinal inflammation, and two fecal markers of increased intestinal permeability (alpha-1-antitrypsin and zonulin) were significantly elevated in PD patients compared to age-matched controls. Lactoferrin, as a second fecal marker of intestinal inflammation, showed a non-significant trend towards elevated concentrations in PD patients. None of the four fecal markers correlated with disease severity, PD subtype, dopaminergic therapy, or presence of constipation. Fecal markers reflecting intestinal inflammation and increased intestinal permeability have been primarily investigated in inflammatory bowel disease so far. Our data indicate that calprotectin, alpha-1-antitrypsin and zonulin could be useful non-invasive markers in PD as well. Even though these markers are not disease-specific, they corroborate the hypothesis of an intestinal inflammation as contributing factor in the pathogenesis of PD. Further investigations are needed to determine whether calprotectin, alpha-1-antitrypsin and zonulin can be used to define PD subgroups and to monitor the effect of interventions in PD. Copyright © 2018 Elsevier Ltd. All rights reserved.

  16. Proceso de pruebas para pequeñas organizaciones desarrolladoras de software

    Directory of Open Access Journals (Sweden)

    Martha Lucía Rojas-Montes

    2015-05-01

    Full Text Available Definir un proceso de pruebas dentro de una organización puede ser valioso en la medida en que permita: (i incrementar la calidad del producto, (ii facilitar la comunicación y la comprensión entre los miembros del equipo, (iii apoyar la mejora continua del proceso, y (iv soportar la ejecución automática de ciertas tareas. En este sentido, este artículo propone un proceso liviano definido para guiar y apoyar la realización de las pruebas en pequeñas organizaciones desarrolladoras de software. El proceso propuesto incorpora técnicas de pruebas funcionales con el objetivo de concretar las actividades requeridas para evaluar la funcionalidad de un producto software de manera organizada y sistemática, especialmente aquellas que tienen que ver con el diseño y ejecución de las pruebas. Este proceso ha sido definido a partir del análisis de los procesos de pruebas existentes en algunos modelos de referencia y en diferentes estudios revisados de la literatura. Tras su ejecución exitosa en una pequeña empresa de desarrollo software, se ha observado que este proceso puede ser útil y práctico para llevar a cabo las pruebas de un producto software por organizaciones de este tipo.

  17. Expectativas, logros y frustraciones de un proceso de paz

    Directory of Open Access Journals (Sweden)

    Javier Giraldo Moreno

    2017-11-01

    Full Text Available Los diálogos de Paz entre el Gobierno de Colombia y la insurgencia de las FARC, iniciados formalmente en agosto de 2012, luego de un período previo de exploración, y concluidos formalmente en noviembre de 2016 con la firma de un extenso Acuerdo que ha sufrido múltiples enmiendas y que no acaba de consolidarse frente a perspectivas constantes de nuevas enmiendas y amenazas persistentes de desconocimiento e incumplimiento, han centrado el debate político interno y externo. A nivel interno la polarización se agudiza progresivamente; a nivel externo produce curiosidades y expectativas por lo novedoso de algunas de sus soluciones. En los últimos 34 años Colombia había vivido 5 prolongados procesos de paz, todos fracasados, si se entiende la paz como algo de interés nacional. Sólo entre los gobiernos de Barco y Gaviria (1986-94 hubo desmovilizaciones de varias estructuras armadas pequeñas o diezmadas que no se proyectaron en ninguna reforma social sino en prebendas puntuales para cada desmovilizado. Ello ha incidido en una cierta banalización de la paz, no pocas veces utilizada como incentivo de politiquerías electorales.

  18. El trabajo en equipo en el Proceso Administrativo y de Compras en OPL Carga de Bucaramanga

    OpenAIRE

    Silva Remolina, Maria Andrea

    2014-01-01

    El proceso administrativo y de compras de OPL Carga tiene algunas falencias entre ellas: fallas en la Comunicación entre el personal operativo, no se realizan llamadas internas usando con frecuencia el email, produciendo la saturación de solicitudes las cuales terminan sin ser resueltas en cuanto a roles se refiere, no hay enfoque de procesos en vista que no se tiene claras las tareas de cada cargo, adicionalmente no hay claridad en los subprocesos, perjudicando el proceso con el a...

  19. El proceso de requisitos en el desarrollo de open source software

    OpenAIRE

    Muruzábal Ishigetani, Olympia

    2014-01-01

    El propósito de este trabajo es determinar si las actividades que se llevan a cabo en el proceso de requisitos en comunidades OSS, a diferencia del proceso de requisitos de la Ingeniería del Software tradicional, es una de las claves del éxito del software de código abierto. El proceso de requisitos forma parte de la etapa inicial de un proyecto y es imprescindible puesto que define las funcionalidades del software a desarrollar y da soporte a la adaptación y evolución del proy...

  20. Proceso de pruebas para pequeñas organizaciones desarrolladoras de software

    OpenAIRE

    Martha Lucía Rojas-Montes; Francisco José Pino-Correa; James Mauricio Martínez

    2015-01-01

    Definir un proceso de pruebas dentro de una organización puede ser valioso en la medida en que permita: (i) incrementar la calidad del producto, (ii) facilitar la comunicación y la comprensión entre los miembros del equipo, (iii) apoyar la mejora continua del proceso, y (iv) soportar la ejecución automática de ciertas tareas. En este sentido, este artículo propone un proceso liviano definido para guiar y apoyar la realización de las pruebas en pequeñas organizaciones desarrolladoras de softwa...

  1. Modelo Gestión Documental para optimizar procesos en la ESPOCH

    OpenAIRE

    Reina Haro, Diego Marcelo

    2012-01-01

    Se presenta la propuesta de “Modelo de Gestión Documental para optimizar procesos en la ESPOCH”, con la visión de optimizar recursos en el proceso de remuneraciones de la institución. Los empleados, trabajadores, beneficiarios y encargados de producir, manipular y consultar este tipo de documentación obtendrán los conocimientos necesarios en cuanto a gestión documental y los procesos archivísticos para determinar el contenido de documentos, oficios, roles , etc. y mantenerlos organizados. Se ...

  2. El discurso sobre el actual proceso de paz en la revista Semana (2012-2014)

    OpenAIRE

    Rincón Henao, Diana Marcela

    2016-01-01

    Este artículo presenta un análisis sobre el discurso del actual proceso de paz en la revista Semana entre los años 2012 a 2014, dada la relevancia de la participación de los medios de comunicación en un proceso trascendental para el futuro del país y la reconciliación de la sociedad. El objetivo es describir qué estrategias argumentativas usa la revista a partir de las noticias sobre el proceso de paz durante este periodo. La metodología utilizada se basó en los esquemas argumentativos (top...

  3. LA CLAVE DEL ÉXITO DE UN PROCESO DE AUTOEVALUACIÓN: SU EQUIPO

    OpenAIRE

    Gutiérrez Huby, Ana María

    2014-01-01

    La experiencia obtenida en la conducción del proceso de autoevaluación de la Facultad de Ciencias Contables de esta universidad, el cual se encuentra en su fase final, nos da la certeza de expresar con mayor seguridad la importancia plena del rol que desempeñan los equipos de autoevaluación, ya que como ejecutores del proceso, tienen la responsabilidad de llevar a cabo de manera permanente y comprometida todas las acciones que involucra el proceso en todas las etapas del mismo. Por ello ...

  4. Propuesta metodológica: proceso de selección de directores para colegios municipales

    Directory of Open Access Journals (Sweden)

    Oscar Rojas Carrasco

    2015-04-01

    Full Text Available Esta publicación se centra en el proceso de selección de Directores de Colegio. El origen del problema de investigación radica en la necesidad de optimizar un proceso de selección para docentes directivos con la finalidad que pueda ser utilizado por cualquier Sostenedor Municipal. La propuesta incorpora un proceso de selección en tres etapas, manteniendo aquellos elementos de la selección tradicional que son relevantes e incorpora elementos nuevos que marcan el énfasis en las competencias del candidato.

  5. El carácter privado del proceso de inaplicabilidad por inconstitucionalidad

    OpenAIRE

    Bronfman, Alan

    2011-01-01

    El proceso de inaplicabilidad debe su estructura al modelo tradicional de litigación privada. En su seno acoge el trámite de un recurso que también nace de un litigio construido siguiendo el modelo de proceso privado. En este artículo se examinan algunas de las dificultades que surgen del uso de este modelo en un proceso de control concreto de constitucionalidad que contienes intereses y objetivos que se distancian de la litigación privada. The structure of the non-applicability process is...

  6. A new approach to predict human intestinal absorption using porcine intestinal tissue and biorelevant matrices

    NARCIS (Netherlands)

    Westerhout, J.; Steeg, E. van de; Grossouw, D.; Zeijdner, E.E.; Krul, C.A.M.; Verwei, M.; Wortelboer, H.M.

    2014-01-01

    A reliable prediction of the oral bioavailability in humans is crucial and of high interest for pharmaceutical and food industry. The predictive value of currently used in silico methods, in vitro cell lines, ex vivo intestinal tissue and/or in vivo animal studies for human intestinal absorption,

  7. The intestinal complement system in inflammatory bowel disease: Shaping intestinal barrier function.

    Science.gov (United States)

    Sina, Christian; Kemper, Claudia; Derer, Stefanie

    2018-06-01

    The complement system is part of innate sensor and effector systems such as the Toll-like receptors (TLRs). It recognizes and quickly systemically and/or locally respond to microbial-associated molecular patterns (MAMPs) with a tailored defense reaction. MAMP recognition by intestinal epithelial cells (IECs) and appropriate immune responses are of major importance for the maintenance of intestinal barrier function. Enterocytes highly express various complement components that are suggested to be pivotal for proper IEC function. Appropriate activation of the intestinal complement system seems to play an important role in the resolution of chronic intestinal inflammation, while over-activation and/or dysregulation may worsen intestinal inflammation. Mice deficient for single complement components suffer from enhanced intestinal inflammation mimicking the phenotype of patients with chronic inflammatory bowel disease (IBD) such as Crohn's disease (CD) or ulcerative colitis (UC). However, the mechanisms leading to complement expression in IECs seem to differ markedly between UC and CD patients. Hence, how IECs, intestinal bacteria and epithelial cell expressed complement components interact in the course of IBD still remains to be mostly elucidated to define potential unique patterns contributing to the distinct subtypes of intestinal inflammation observed in CD and UC. Copyright © 2018 Elsevier Ltd. All rights reserved.

  8. Intestinal ischemia-reperfusion injury augments intestinal mucosal injury and bacterial translocation in jaundiced rats.

    Science.gov (United States)

    Yüksek, Yunus Nadi; Kologlu, Murat; Daglar, Gül; Doganay, Mutlu; Dolapci, Istar; Bilgihan, Ayse; Dolapçi, Mete; Kama, Nuri Aydin

    2004-01-01

    The aim of this study was to evaluate local effects and degree of bacterial translocation related with intestinal ischemia-reperfusion injury in a rat obstructive jaundice model. Thirty adult Sprague-Dawley rats (200-250 g) were divided into three groups; including Group 1 (jaundice group), Group 2 (jaundice-ischemia group) and Group 3 (ischemia group). All rats had 2 laparotomies. After experimental interventions, tissue samples for translocation; liver and ileum samples for histopathological examination, 25 cm of small intestine for mucosal myeloperoxidase and malondialdehyde levels and blood samples for biochemical analysis were obtained. Jaundiced rats had increased liver enzyme levels and total and direct bilirubin levels (p<0.05). Intestinal mucosal myeloperoxidase and malondialdehyde levels were found to be high in intestinal ischemia-reperfusion groups (p<0.05). Intestinal mucosal damage was more severe in rats with intestinal ischemia-reperfusion after bile duct ligation (p<0.05). Degree of bacterial translocation was also found to be significantly high in these rats (p<0.05). Intestinal mucosa is disturbed more severely in obstructive jaundice with the development of ischemia and reperfusion. Development of intestinal ischemia-reperfusion in obstructive jaundice increases bacterial translocation.

  9. Plasma intestinal fatty acid binding protein (I-FABP) concentrations increase following intestinal ischemia in pigs

    NARCIS (Netherlands)

    Niewold, T.A.; Meinen, M.; Meulen, van der J.

    2004-01-01

    Intestinal fatty acid binding protein (I-FABP) is an intracellular epithelial protein in the intestinal mucosa of many animals. IFABP appears in the circulation following epithelial damage, and in humans, is proven to be a parameter for damage to the mucosa. In this paper, an ELISA test designed for

  10. Presentation of a nationwide multicenter registry of intestinal failure and intestinal transplantation

    NARCIS (Netherlands)

    Neelis, E. G.; Roskott, A. M.; Dijkstra, G.; Wanten, G. J.; Serlie, M. J.; Tabbers, M. M.; Damen, G.; Olthof, E. D.; Jonkers, C. F.; Kloeze, J. H.; Ploeg, R. J.; Imhann, F.; Nieuwenhuijs, V. B.; Rings, E. H. H. M.

    2016-01-01

    Exact data on Dutch patients with chronic intestinal failure (CIF) and after intestinal transplantation (ITx) have been lacking. To improve standard care of these patients, a nationwide collaboration has been established. Objectives of this study were obtaining an up-to-date prevalence of CIF and

  11. Presentation of a nationwide multicenter registry of intestinal failure and intestinal transplantation

    NARCIS (Netherlands)

    Neelis, E. G.; Roskott, A. M.; Dijkstra, G.; Wanten, G. J.; Serlie, M. J.; Tabbers, M. M.; Damen, G.; Olthof, E. D.; Jonkers, C. F.; Kloeze, J. H.; Ploeg, R. J.; Imhann, F.; Nieuwenhuijs, V. B.; Rings, E. H. H. M.

    Background & aims: Exact data on Dutch patients with chronic intestinal failure (CIF) and after intestinal transplantation (ITx) have been lacking. To improve standard care of these patients, a nationwide collaboration has been established. Objectives of this study were obtaining an up-to-date

  12. Presentation of a nationwide multicenter registry of intestinal failure and intestinal transplantation

    NARCIS (Netherlands)

    Neelis, E.G.; Roskott, A.M.; Dijkstra, G.; Wanten, G.J.A.; Serlie, M.J.; Tabbers, M.M.; Damen, G.M.; Olthof, E.D.; Jonkers, C.F.; Kloeze, J.H.; Ploeg, R.J.; Imhann, F.; Nieuwenhuijs, V.B.; Rings, E.H.

    2016-01-01

    BACKGROUND & AIMS: Exact data on Dutch patients with chronic intestinal failure (CIF) and after intestinal transplantation (ITx) have been lacking. To improve standard care of these patients, a nationwide collaboration has been established. Objectives of this study were obtaining an up-to-date

  13. [Myosin B ATPase activity of the intestinal smooth muscle in intestinal obstruction].

    Science.gov (United States)

    Takamatsu, H

    1983-06-01

    Intestinal smooth myosin B was prepared from muscle layers around the lesion in dogs with experimental colonic stenosis and in patients with congenital intestinal obstruction. Mg2+-ATPase activity of the myosin B was compared between the proximal dilated segment and distal segment to obstruction. Experimental colonic stenosis: In early period after surgery, proximal colons showed higher activity of myosin B ATPase than distal colons, decreasing to less than distal colon as time passed. Congenital intestinal obstruction: In three cases, whose atresia might have occurred at earlier period of gestation, proximal bowels showed less activity of myosin B ATPase than distal bowels. However, in two cases, whose atresia might have occurred at later period of gestation, and two cases with intestinal stenosis, proximal bowels indicated higher activity of myosin B ATPase than distal bowels. These data suggested that the contractibility of the proximal intestine was depending on the duration of obstruction, and it was depressed in the former patients and was accelerated in the latter patients. These results suggested that the extensive resection of dilated proximal bowel in the congenital atresia is not always necessary to obtain good postoperative intestinal dynamics at the operation of the atresial lesions which may be induced at later period of gestation. They also suggested that surgery for intestinal obstruction should be performed before the depression of intestinal contractibility to get good bowel function.

  14. Coagulation of sheep intestinal and prefemoral lymph.

    Science.gov (United States)

    Hanley, C A; Johnston, M G; Nelson, W

    1988-06-01

    We have determined the most suitable method for the automated analysis of the clotting parameters in sheep intestinal and prefemoral lymph as defined by the Activated Partial Thromboplastin Times (APTT; measure of intrinsic coagulation pathway) and the Prothrombin Times (PT; measure of extrinsic coagulation pathway). As opposed to optical density systems, the use of a Fibro-System Fibrometer was found to provide the most consistent assessment of coagulation with the endpoint being the time to fibrin strand formation. We measured APTT in sheep intestinal and prefemoral lymph of 59.78 +/- 7.69 seconds and 51.03 +/- 10.49 seconds respectively. These values were more prolonged than those obtained from sheep blood plasma but only in the case of intestinal lymph were the differences significant (p less than 0.025). Human blood APTT values were significantly less than both sheep blood (p less than 0.05) and sheep intestinal (p less than 0.001) and prefemoral lymph (p less than 0.01). PT values were found to be 21.56 +/- 1.14 seconds in intestinal and 22.00 +/- 1.88 seconds in prefemoral lymph. These values were also significantly greater than those obtained from sheep blood (both p less than 0.001). Human blood PTs were significantly less than both sheep blood (p less than 0.001) and intestinal and prefemoral lymph (both p less than 0.001). Measurement of APTT and PT values in intestinal lymph and PT determinations in prefemoral lymph were not affected by storage in the refrigerator or freezer. There was some indication that APTT values in prefemoral samples were susceptible to storage artifacts; however, the differences in coagulation times were not significant.

  15. Neonatal intestinal obstruction in Benin, Nigeria

    Directory of Open Access Journals (Sweden)

    Osifo Osarumwense

    2009-01-01

    Full Text Available Background: Intestinal obstruction is a life threatening condition in the newborn, with attendant high mortality rate especially in underserved subregion. This study reports the aetiology, presentation, and outcome of intestinal obstruction management in neonates. Materials and Methods: A prospective study of neonatal intestinal obstruction at the University of Benin Teaching Hospital, Benin, Nigeria, between January 2006-June 2008. Data were collated on a structured proforma and analysed for age, sex, weight, presentation, type/date of gestation/delivery, aetiology, clinical presentation, associated anomaly, treatment, and outcome. Results: There were 71 neonates, 52 were males and 19 were females (2.7:1. Their age range was between 12 hours and 28 days (mean, 7.9 ± 2.7 days and they weighed between 1.8 and 5.2 kg (average, 3.2 kg. The causes of intestinal obstruction were: Anorectal anomaly, 28 (39.4%; Hirschsprung′s disease, 8 (11.3%′ prematurity, 3 (4.2%; meconeum plug, 2 (2.8%; malrotation, 6 (8.5%; intestinal atresia, 8 (11.3%; necrotising enterocolitis (NEC, 4 (5.6%; obstructed hernia, 4 (5.6%; and spontaneous gut perforation, 3 (4.2%. Also, 27 (38% children had colostomy, 24 (33.8% had laparotomy, 9 (12.8% had anoplasty, while 11 (15.4% were managed nonoperatively. A total of 41 (57.7% neonates required incubator, 26 (36.6% needed total parenteral nutrition, while 15 (21.1% require d paediatric ventilator. Financial constraint, late presentation, presence of multiple anomalies, aspiration, sepsis, gut perforation, and bowel gangrene were the main contributors to death. Neonates with lower obstructions had a better outcome compared to those having upper intestinal obstruction ( P < 0.0001. Conclusion: Outcomes of intestinal obstruction are still poor in our setting; late presentation, financial constraints, poor parental motivation and lack of basic facilities were the major determinants of mortality.

  16. Desafíos educativos en tiempos de auto-comunicación masiva: la interlocución de las audiencias Educational Challenges in Times of Mass Self-communication: A Dialogue among Audience

    Directory of Open Access Journals (Sweden)

    Agustín García Matilla

    2012-03-01

    Full Text Available En este texto se abordan esencialmente dos temas. En primer lugar, los cambios emergentes en el estar como audiencias frente a nuevos y viejos medios y, en segundo lugar, los procesos múltiples de recepción e interlocución que hoy experimentan. Se argumenta que las audiencias sin perder siempre ese rol, están también asumiendo otros más activos e interactuando cada vez más como noveles productores y emisores de contenidos mediáticos, similares a los que intercambian a través de diversos lenguajes, formatos y dispositivos tecnológicos. Se destaca la necesidad de diferenciar el consumo amplificado y la gran conectividad existente, de una auténtica interlocución horizontal, creativa y propositiva de los interlocutores. Por otra parte, se presenta una propuesta educomunicativa acorde con esta realidad polimorfa y cambiante de las audiencias, que rescata la tradición pedagógico-crítica iberoamericana y que se desarrolla en la Universidad de Valladolid, Campus de Segovia. La asignatura «Comunicación, educación y sociedad en el contexto digital» se programa en los estudios de Comunicación de esta Universidad con el objetivo de desarrollar y fortalecer aquellas capacidades, destrezas y reflexiones apropiadas para una interlocución más integral en el mundo de la educomunicación. El principal objetivo de la educación en competencia comunicativa, educación en medios y alfabetización digital es educar en las técnicas y estrategias para el análisis y producción de contenidos en medios. En este artículo se subraya la gran complejidad comunicativa y cultural que conllevan los esfuerzos educativos en esta dirección.This text is an approach on two leading topics: the changes emerging in the way audiences deal with new and old media, and, the multiple processes of reception and interaction occurring as a result of the information and communication systems. Audiences are seemingly devising new roles as creators and emitters of media

  17. Intestinal Leiomyositis: A Cause of Chronic Intestinal Pseudo-Obstruction in 6 Dogs.

    Science.gov (United States)

    Zacuto, A C; Pesavento, P A; Hill, S; McAlister, A; Rosenthal, K; Cherbinsky, O; Marks, S L

    2016-01-01

    Intestinal leiomyositis is a suspected autoimmune disorder affecting the muscularis propria layer of the gastrointestinal tract and is a cause of chronic intestinal pseudo-obstruction in humans and animals. To characterize the clinical presentation, histopathologic features, and outcome of dogs with intestinal leiomyositis in an effort to optimize treatment and prognosis. Six client-owned dogs. Retrospective case series. Medical records were reviewed to describe signalment, clinicopathologic and imaging findings, histopathologic diagnoses, treatment, and outcome. All biopsy specimens were reviewed by a board-certified pathologist. Median age of dogs was 5.4 years (range, 15 months-9 years). Consistent clinical signs included vomiting (6/6), regurgitation (2/6), and small bowel diarrhea (3/6). Median duration of clinical signs before presentation was 13 days (range, 5-150 days). Diagnostic imaging showed marked gastric distension with dilated small intestines in 4/6 dogs. Full-thickness intestinal biopsies were obtained in all dogs by laparotomy. Histopathology of the stomach and intestines disclosed mononuclear inflammation, myofiber degeneration and necrosis, and fibrosis centered within the region of myofiber loss in the intestinal muscularis propria. All dogs received various combinations of immunomodulatory and prokinetic treatment, antimicrobial agents, antiemetics, and IV fluids, but none of the dogs showed a clinically relevant improvement with treatment. Median survival was 19 days after diagnosis (range, 3-270 days). Intestinal leiomyositis is a cause of intestinal pseudo-obstruction and must be diagnosed by full-thickness intestinal biopsy. This disease should be considered in dogs with acute and chronic vomiting, regurgitation, and small bowel diarrhea. Copyright © 2015 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine.

  18. Intestinal cytochromes P450 regulating the intestinal microbiota and its probiotic profile

    Directory of Open Access Journals (Sweden)

    Eugenia Elefterios Venizelos Bezirtzoglou

    2012-09-01

    Full Text Available Cytochromes P450 (CYPs enzymes metabolize a large variety of xenobiotic substances. In this vein, a plethora of studies were conducted to investigate their role, as cytochromes are located in both liver and intestinal tissues. The P450 profile of the human intestine has not been fully characterized. Human intestine serves primarily as an absorptive organ for nutrients, although it has also the ability to metabolize drugs. CYPs are responsible for the majority of phase I drug metabolism reactions. CYP3A represents the major intestinal CYP (80% followed by CYP2C9. CYP1A is expressed at high level in the duodenum, together with less abundant levels of CYP2C8-10 and CYP2D6. Cytochromes present a genetic polymorphism intra- or interindividual and intra- or interethnic. Changes in the pharmacokinetic profile of the drug are associated with increased toxicity due to reduced metabolism, altered efficacy of the drug, increased production of toxic metabolites, and adverse drug interaction. The high metabolic capacity of the intestinal flora is due to its enormous pool of enzymes, which catalyzes reactions in phase I and phase II drug metabolism. Compromised intestinal barrier conditions, when rupture of the intestinal integrity occurs, could increase passive paracellular absorption. It is clear that high microbial intestinal charge following intestinal disturbances, ageing, environment, or food-associated ailments leads to the microbial metabolism of a drug before absorption. The effect of certain bacteria having a benefic action on the intestinal ecosystem has been largely discussed during the past few years by many authors. The aim of the probiotic approach is to repair the deficiencies in the gut flora and establish a protective effect. There is a tentative multifactorial association of the CYP (P450 cytochrome role in the different diseases states, environmental toxic effects or chemical exposures and nutritional status.

  19. Transformación de procesos de desarrollo de software tipo SPEM a procesos workflow : Una propuesta de caso de estudio: SmallRUP

    OpenAIRE

    Zorzán, Fabio Andrés; Riesco, Daniel Eduardo; Szasz, Nora

    2009-01-01

    Esta línea de investigación pretende aportar a la mejora de los procesos de desarrollo de software, en particular los especificados con el Software Process Engineering Metamodel versión 2 (SPEM). El caso de estudio propuesto consiste en transformar la especificación en SPEM de la metodología de desarrollo SmallRUP a una especificación de procesos que pueda ser utilizada como entrada de un motor workflow estándar. Para realizar esta transformación, se utilizará una transformación definida en e...

  20. Combinación de procesos de oxidación avanzada y procesos anaerobios para tratamiento de aguas residuales hospitalarias

    OpenAIRE

    , Carlos; Chaparro, Tatiana

    2014-01-01

    Las aguas residuales hospitalarias son una de las principalesfuentes de contaminantes emergentes (e.g. antibióticos,antiepilépticos, hormonas). Debido a la baja eficiencia de los procesos convencionales usados en las plantas de tratamiento de aguas residuales municipales, para eliminar la materia orgánica de este origen, combinar procesos de oxidación avanzada con tratamientos biológicos, surge como una alternativa para reducir el impacto en en el ambiente de estas aguas residuales. Con base ...

  1. Panel. Uso de los medios masivos en los procesos educativos

    Directory of Open Access Journals (Sweden)

    José Rivero

    2015-01-01

    Full Text Available A juicio de José Rivero (OREALC/ UNESCO, moderador del panel que transcribimos, la vinculación Educación Comunicación a lo largo del Seminario fue un éxito. "Hubo un gran esfuerzo por definir la comunicación y las diferentes formas y modos de entenderla con fines educativos", dijo Rivero. Sin embargo, consideró que en relación a la denominada educación no formal faltó énfasis en cuanto a precisar las diferentes pedagogías que han surgido en Amé­rica Latina al momento de asociar el uso de los medios masivos con los procesos educativos. Al seminario asistieron un selecto grupo de participantes, con la finalidad de completar la visión general de las ponencias, debates y comentarios presentados en el encuentro. En el mismo participaron: Remando Martínez (Centro de Investigación y Educación Popular-CINEP, Colombia; Fernando García (Instituto Central de Ciencias Pedagógicas del Ministerio de Educación, Cuba; Carlos Núñez (Instituto Mexicano para el Desarrollo Comunitario -IMDEC A.C., México; Mario Kaplún, (Centro al Servicio de la Acción Popular -CESAP, Venezuela; Francisco Gutiérrez (Instituto Latinoamericano de Pedagogía de la Comunicación -IMPEC, Costa Rica; y Arturo Matute (OREALC/UNESCO, Chile.

  2. Afrontar el proceso de duelo To deal with grief

    Directory of Open Access Journals (Sweden)

    Mª Trinidad Pérez Vallejo

    2008-06-01

    Full Text Available Ana, con su testimonio y con su vida nos enseña como afrontar los procesos de duelo. La muerte de su esposo se produce en febrero de 2005, este suceso fue probablemente la experiencia más difícil e importante que ha pasado durante sus 74 años de vida. Ana cuidó a su esposo durante la enfermedad con celo, dedicación y sobre todo con mucho amor. Ahora nos cuenta su experiencia para que pueda servir a aliviar a todas aquellas personas que se hallan en una situación semejante, a la vez, que rinde homenaje a su esposo que con su vida llena de salud y vitalidad le enseñó a morir. Ana tiene una vida plena dedicada a ayudar a los más necesitados, y canaliza esa ayuda con la gente de su barrio visitando a los enfermos, a los que se encuentran solos y los que tienen condiciones económicas más adversas.Anne, in her testimony and life, teaches us how to deal with grief. The death of her husband, on February, 2005, was probably the most difficult and important occurance in the 74 years of her life. Anne had cared for her husband with zeal, dedication and most importantly, love. Anne shares her experience with us so that it may help to alleviate those of us who find ourselves in a similar situation, and at the same time, pays homage to her husband who, when he was filled whit health and vitality, taught to die. Now Anne has a full life dedicated to helping the most needy as she channels this help through the people of her neighbourhood, visiting the ill, the lonely and those in the most adverse economic circumstances.

  3. SISTEMAS TUTORES INTELIGENTES COMO APOYO EN EL PROCESO DE APRENDIZAJE

    Directory of Open Access Journals (Sweden)

    Edwin Eduardo Millan Rojas

    2015-09-01

    Full Text Available El objetivo principal de este artículo es la identificación de las principales características de los tutores inteligentes, su origen y evolución los cuales pueden ofrecer elementos para la formulación de nuevos proyectos de investigación relacionados con la educación y el uso de los tutores. El método utilizado es el descriptivo y sistémico, los cuales permiten recopilar los datos necesarios, la información presentada ha sido adquirida de bases de datos especializadas como IEEE, Redalyc, ACM y Science Direct, además de artículos de revistas de universidades internacionales y de proyectos de investigación descargados de Google Académico. Los Sistemas Tutores Inteligentes surgieron al combinar técnicas de inteligencia artificial (IA con los métodos clásicos de enseñanza. Estos son sistemas de software que generan un ambiente idóneo para la interacción y satisfacción de las necesidades del estudiante, adaptable a los conocimientos previos y a la capacidad de evolución de cada alumno respecto a un área del conocimiento. El funcionamiento de los STI se basa en la relación entre tres principales módulos (tutor, estudiante y dominio, para presentar al usuario la información de manera estructurada. La investigación llevada a cabo permitió reunir los aspectos más relevantes de los Sistemas Tutores Inteligentes (STI y presentarlos como una herramienta óptima para llevar a cabo un proceso de aprendizaje.

  4. Proceso de reconstitución familiar: etapas y tareas

    Directory of Open Access Journals (Sweden)

    Ilein Morales Ramos

    2014-04-01

    Full Text Available Introducción: la formación de nuevas familias con antecedentes de frustración de proyectos de vida familiar es una tendencia en Pinar del Río, que coexiste con la inexistencia de pautas de organización para el logro del proyecto actual. Objetivo: caracterizar el proceso de reconstitución familiar en familias de la ciudad de Pinar del Río que transitan el mismo entre los dos a cinco años de su constitución. Material y métodos: investigación descriptiva de estudio de casos múltiples que respondió a la metodología cualitativa. Se estudiaron trece familias pertenecientes al Policlínico Universitario "Luis Augusto Turcios Lima" en el año 2012. Las técnicas aplicadas fueron: entrevistas individual y familiar, curva familiar, mapa familiar, escudo familiar, curva de la vida familiar, dibujo de la familia y escala valorativa. Resultados: predominaron sentimientos de fracaso que influyeron en las expectativas de las personas para conceptualizar la nueva familia y la diferenciación entre la familia tradicional y la nueva familia, en la primera etapa. La segunda etapa se caracterizó por la distribución de tareas familiares por el subsistema parental dirigidas a la reestructuración de roles en detrimento de la resolución de conflictos emocionales. Conclusiones: fueron identificadas dos etapas delimitadas por el tránsito a la convivencia. No se reconoció la necesidad de proyectar acciones en función de los cambios en la familia, por lo que las tareas cumplidas tuvieron un carácter predominantemente espontáneo. Las familias le otorgaron una doble valencia a la reconstitución familiar.

  5. El corazón endocrino y el proceso inflamatorio

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    Tsuneo Ogawa

    2013-12-01

    Full Text Available El corazón endocrino, a través de sus hormonas polipéptidas atrial natriuretic factor (ANF o ANP y brain natriuretic peptide (BNP, contribuye a regular la precarga y la poscarga cardiacas. Otras importantes funciones se han descubierto recientemente incluyendo interacciones con el sistema inmunológico. Los niveles plasmáticos de BNP, no así los de ANF, aumentan durante un episodio de rechazo agudo del corazón alotransplantado pero retornan a niveles anteriores al episodio de rechazo después de un tratamiento exitoso del tal rechazo. Este fue el primer indicio que involucró el BNP y el sistema inmunológico. Otras patologías que tienen componentes inflamatorios también se ven acompañadas con cambios en la producción del BNP. El aumento del BNP tiene como base el aumento de la actividad transcripcional del gen inducida por citoquinas y substancias relacionadas. In vitro se puede demostrar que este aumento tiende a modular la actividad inmunológica. Inflamación y cambios hemodinámicos co-existen en la mayoría de las enfermedades cardiovasculares y por ende, es posible que sea beneficioso medir las dos hormonas como biomarcadores de cambios de volumen intravascular (ANF y de estos cambios más inflamación (BNP. Cambios en plasma de ANF relativamente más grandes que aquellos de BNP podrían indicar un deterioro hemodinámico, mientras que cambios importantes en BNP podrían ser indicativos de recrudecimiento del proceso inflamatorio.

  6. Intestinal endocrine cells in radiation enteritis

    International Nuclear Information System (INIS)

    Pietroletti, R.; Blaauwgeers, J.L.; Taat, C.W.; Simi, M.; Brummelkamp, W.H.; Becker, A.E.

    1989-01-01

    In this study, the intestinal endocrine cells were investigated in 13 surgical specimens affected by radiation enteritis. Endocrine cells were studied by means of Grimelius' silver staining and immunostaining for chromogranin, a general marker of endocrine cells. Positively stained cells were quantified by counting their number per unit length of muscularis mucosa. Results in radiation enteritis were compared with matched control specimens by using Student's t test. Chromogranin immunostaining showed a statistically significant increase of endocrine cells in radiation enteritis specimens compared with controls both in small and large intestine (ileum, 67.5 +/- 23.5 cells per unit length of muscularis mucosa in radiation enteritis versus 17.0 +/- 6.1 in controls; colon, 40.9 +/- 13.7 cells per unit length of muscularis mucosa in radiation enteritis versus 9.5 +/- 4.1 in controls--p less than 0.005 in both instances). Increase of endocrine cells was demonstrated also by Grimelius' staining; however, without reaching statistical significance. It is not clear whether or not the increase of endocrine cells in radiation enteritis reported in this study is caused by a hyperplastic response or by a sparing phenomenon. We should consider that increased endocrine cells, when abnormally secreting their products, may be involved in some of the clinical features of radiation enteropathy. In addition, as intestinal endocrine cells produce trophic substances to the intestine, their increase could be responsible for the raised risk of developing carcinoma of the intestine in long standing radiation enteritis

  7. Macrophages in intestinal homeostasis and inflammation

    Science.gov (United States)

    Bain, Calum C; Mowat, Allan McI

    2014-01-01

    The intestine contains the largest pool of macrophages in the body which are essential for maintaining mucosal homeostasis in the face of the microbiota and the constant need for epithelial renewal but are also important components of protective immunity and are involved in the pathology of inflammatory bowel disease (IBD). However, defining the biological roles of intestinal macrophages has been impeded by problems in defining the phenotype and origins of different populations of myeloid cells in the mucosa. Here, we discuss how multiple parameters can be used in combination to discriminate between functionally distinct myeloid cells and discuss the roles of macrophages during homeostasis and how these may change when inflammation ensues. We also discuss the evidence that intestinal macrophages do not fit the current paradigm that tissue-resident macrophages are derived from embryonic precursors that self-renew in situ, but require constant replenishment by blood monocytes. We describe our recent work demonstrating that classical monocytes constantly enter the intestinal mucosa and how the environment dictates their subsequent fate. We believe that understanding the factors that drive intestinal macrophage development in the steady state and how these may change in response to pathogens or inflammation could provide important insights into the treatment of IBD. PMID:24942685

  8. Tissue response after radiation exposure. Intestine

    International Nuclear Information System (INIS)

    Otsuka, Kensuke; Tomita, Masanori; Yamauchi, Motohiro; Iwasaki, Toshiyasu

    2014-01-01

    Gastrointestinal syndrome followed by 'gut death' is due to intestinal disorders. This syndrome is induced by high-dose (>10 Gy) of ionizing radiation. Recovery from the gastrointestinal syndrome would depend on the number of survived clonogens and regeneration capability of crypts. These tissue alterations can be observed by high-dose radiation, however, cellular dynamics in crypts can be affected by low-dose radiation. For example, Potten et al. found that low-dose radiation induce apoptosis of intestinal stem cells, which produce all differentiated function cells. Recently, intestinal stem cells are characterized by molecular markers such as Lgr5. Since intestinal adenomas can be induced by deletion of Apc gene in Lgr5 + stem cells, it is widely recognized that Lgr5 + stem cells are the cell-of-origin of cancer. Duodenal Lgr5 + stem cells are known as radioresistant cells, however, we found that ionizing radiation significantly induces the turnover of colonic Lgr5 + stem cells. Combined with the knowledge of other radioresistant markers, stem-cell dynamics in tissue after irradiation are becoming clear. The present review introduces the history of gastrointestinal syndrome and intestinal stem cells, and discusses those future perspectives. (author)

  9. Small Intestinal Obstruction Caused by Anisakiasis

    Directory of Open Access Journals (Sweden)

    Yuichi Takano

    2013-01-01

    Full Text Available Small intestinal anisakiasis is a rare disease that is very difficult to diagnose, and its initial diagnosis is often surgical. However, it is typically a benign disease that resolves with conservative treatment, and unnecessary surgery can be avoided if it is appropriately diagnosed. This case report is an example of small intestinal obstruction caused by anisakiasis that resolved with conservative treatment. A 63-year-old man admitted to our department with acute abdominal pain. A history of raw fish (sushi ingestion was recorded. Abdominal CT demonstrated small intestinal dilatation with wall thickening and contrast enhancement. Ascitic fluid was found on the liver surface and in the Douglas pouch. His IgE (RIST was elevated, and he tested positive for the anti-Anisakis antibodies IgG and IgA. Small intestinal obstruction by anisakiasis was highly suspected and conservative treatment was performed, ileus tube, fasting, and fluid replacement. Symptoms quickly resolved, and he was discharged on the seventh day of admission. Small intestinal anisakiasis is a relatively uncommon disease, the diagnosis of which may be difficult. Because it is a self-limiting disease that usually resolves in 1-2 weeks, a conservative approach is advisable to avoid unnecessary surgery.

  10. Oído y vencido. El debido proceso en la cultura y la jurisprudencia

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    José Ramón Narváez

    2014-06-01

    Full Text Available El debido proceso es una institución técnica del Derecho que también está presente en la cultura popular. En este sentido, el presente trabajo identifica ciertos momentos emblemáticos en los que la cultura popular habla del aprecio social por la institución del debido proceso, en especial en dos figuras literarias clásicas: Robin Hood y El proceso de Franz Kafka. Finalmente, se muestra cómo la jurisprudencia actual tiene también sus referencias de prioridad respecto de esta institución. La idea es acercar al lector, a través del Debido proceso, a la lectura de la historia, la literatura y de la cultura popular universal donde subyace una idea muy acabada del derecho.

  11. La frontera México-Estados Unidos: dinámicas transfronterizas y procesos de gobernanza

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    María del Rosio Barajas Escamilla

    2016-01-01

    Full Text Available Bajo el proceso de la globalización y los procesos de integración regional, los espacios de frontera experimentan importantes cambios en sus funciones y en su escala de influencia. Así lo muestra la reconfiguración de los espacios fronterizos dentro de la Unión Europea, del Mercosur y en cierta medida en el marco del TLCAN. El objetivo particular del estudio es analizar las características que asume la reconfiguración del territorio de frontera entre México con Estados Unidos y sus nuevos procesos de gobernanza, donde los gobiernos multinivel (nivel trilateral, bilateral, federal, estatal, local y transfronterizo y los organismos privados y de la sociedad civil están llamados a jugar un nuevo papel en el proceso de construcción de una región transfronteriza.

  12. Formación Continuada: El proceso cognitivo y el aprendizaje profesional

    Directory of Open Access Journals (Sweden)

    María Nolla Domenjó

    Full Text Available La investigación en educación médica realizada durante las últimas décadas ha contribuido a poder comprender mejor el proceso de aprendizaje.Los docentes deberían conocer los resultados de estos estudios para poder adecuar los programas de formación a la evidencia disponible.En este artículo se pretende hacer un repaso del estado de la cuestión referente al desarrollo profesional de los médicos. Se considera que el proceso de aprendizaje es un proceso constructivista, autodirigido, colaborativo y contextual. Además de los principios del aprendizaje, se trata el proceso de razonamiento clínico y la importancia de la práctica reflexiva durante toda la vida profesional.

  13. Organización de la seguridad en el proceso constructivo

    Directory of Open Access Journals (Sweden)

    Mínguez Fernández, César

    1993-02-01

    Full Text Available Thorough and complex study on the implementation of prevention processes and labour safety in the production process in Industrial Construction Companies.

    Profundo y complejo estudio sobre la implantación de los procesos de prevención y salud laboral, en el proceso de producción, en la Empresa Industrial de Construcción.

  14. Software para el proceso de selección de personal

    OpenAIRE

    Almagro Rojas, Gustavo

    2010-01-01

    El proyecto nace de la necesidad del departamento de recursos humanos de Aventia s.l. de organizar la información referente a los procesos de selección de personal. Más en concreto resulta muy importante formalizar el proceso de generación de solicitudes y agilizar la gestión de la información referente a los candidatos.

  15. Proceso de virtualización de un centro de procesamiento de datos (CPD)

    OpenAIRE

    Castro Santero, Juan

    2016-01-01

    Este trabajo trata del proceso de virtualización de un centro de procesamiento de datos (CPD), por el que se explica paso a paso este proceso. Aquest treball tracta del procés de virtualització d'un centre de processament de dades (CPD), pel que s'explica pas a pas aquest procés. Bachelor thesis for the Computer Science program.

  16. Relevancia e Inferencia: Procesos cognitivos propios de la comunicación humana

    Directory of Open Access Journals (Sweden)

    Moya Pardo Constanza

    2006-06-01

    Full Text Available Este artículo pretende mostrar los planteamientos cognitivos más representativos de la Teoría de la Relevancia propuesta por Spelber & Wilson con respecto al modelo ostensivoinferencial. Este modelo plantea un mecanismo deductivo explícito que da cuenta de los procesos y estrategias que permiten el paso del significado literal a la interpretación pragmática de los mensajes en el proceso de comunicación humana.

  17. Measures to minimize small intestine injury in the irradiated pelvis

    International Nuclear Information System (INIS)

    Green, N.; Iba, G.; Smith, W.R.

    1975-01-01

    Small intestine injury causes long-term suffering and high mortality. Five of 187 of our patients had developed serious small intestine injury. Four patients had corrective surgery. Three patients died. All were women. Subsequently, all patients who received definitive pelvic irradiation had small intestine roentgenograms to determine its location and mobility. Female patients, thin patients, and elderly patients had larger amounts of small intestine in the whole pelvis, a deeper cul de sac, and a greater incidence of relatively immobile small intestine. Patients with relatively immobile small intestine in the treatment field may be predisposed to injury. There was no relationship of the incidence of relatively immobile small intestine to prior pelvic surgery. We used the findings from the small intestine roentgenograms to modify individually the radiotherapy regimen so as to minimize the risk for small intestine injury. Patients were placed in the prone position to displace the small intestine out of the treatment fields used for booster dose irradiation. The treatment field was modified to exclude the small intestine. The total tumor dose delivered was determined by expectations for cure vs complications. To date, none of the patients in this study group has developed small intestine injury. Cadaver studies showed the feasibility of elective shortening of the pelvic cul de sac. The small intestine can be displaced away from the bladder, prostate, or cervix. (U.S.)

  18. Transcriptome changes during intestinal cell differentiation

    DEFF Research Database (Denmark)

    Tadjali, Mehrdad; Seidelin, Jakob B; Olsen, Jørgen

    2002-01-01

    The expression of 18149 genes have been analysed during the differentiation of the human intestinal cell line Caco-2. cDNA probes from undifferentiated and differentiated Caco-2 cells were separately hybridised to EST DNAs spotted in an array on a nylon membrane. A remarkable change in the transc......The expression of 18149 genes have been analysed during the differentiation of the human intestinal cell line Caco-2. cDNA probes from undifferentiated and differentiated Caco-2 cells were separately hybridised to EST DNAs spotted in an array on a nylon membrane. A remarkable change...... cells by performing reverse transcriptase-polymerase chain reaction on RNA extracted from laser dissected intestinal crypt and villi. In a screen of eight transcripts one - SART3 - was identified as a marker for human colonic crypts....

  19. Mucosal immunity to pathogenic intestinal bacteria.

    Science.gov (United States)

    Perez-Lopez, Araceli; Behnsen, Judith; Nuccio, Sean-Paul; Raffatellu, Manuela

    2016-03-01

    The intestinal mucosa is a particularly dynamic environment in which the host constantly interacts with trillions of commensal microorganisms, known as the microbiota, and periodically interacts with pathogens of diverse nature. In this Review, we discuss how mucosal immunity is controlled in response to enteric bacterial pathogens, with a focus on the species that cause morbidity and mortality in humans. We explain how the microbiota can shape the immune response to pathogenic bacteria, and we detail innate and adaptive immune mechanisms that drive protective immunity against these pathogens. The vast diversity of the microbiota, pathogens and immune responses encountered in the intestines precludes discussion of all of the relevant players in this Review. Instead, we aim to provide a representative overview of how the intestinal immune system responds to pathogenic bacteria.

  20. Primary intestinal lymphangiectasia with generalized warts.

    Science.gov (United States)

    Lee, Soon Jae; Song, Hyun Joo; Boo, Sun-Jin; Na, Soo-Young; Kim, Heung Up; Hyun, Chang Lim

    2015-07-21

    Primary intestinal lymphangiectasia (PIL) is a rare protein-losing enteropathy with lymphatic leakage into the small intestine. Dilated lymphatics in the small intestinal wall and mesentery are observed in this disease. Laboratory tests of PIL patients revealed hypoalbuminemia, lymphocytopenia, hypogammaglobulinemia and increased stool α-1 antitrypsin clearance. Cell-mediated immunodeficiency is also present in PIL patients because of loss of lymphocytes. As a result, the patients are vulnerable to chronic viral infection and lymphoma. However, cases of PIL with chronic viral infection, such as human papilloma virus-induced warts, are rarely reported. We report a rare case of PIL with generalized warts in a 36-year-old male patient. PIL was diagnosed by capsule endoscopy and colonoscopic biopsy with histological tissue confirmation. Generalized warts were observed on the head, chest, abdomen, back, anus, and upper and lower extremities, including the hands and feet of the patient.

  1. Intestinal Failure: New Definition and Clinical Implications.

    Science.gov (United States)

    Kappus, Matthew; Diamond, Sarah; Hurt, Ryan T; Martindale, Robert

    2016-09-01

    Intestinal failure (IF) is a state in which the nutritional demands of the body are not met by the gastrointestinal absorptive surface. It is a long-recognized complication associated with short bowel syndrome, which results in malabsorption after significant resection of the intestine for many reasons or functional dysmotility. Etiologies have included Crohn's disease, vascular complications, and the effects of radiation enteritis, as well as the effects of intestinal obstruction, dysmotility, or congenital defects. While IF has been long-recognized, it has historically not been uniformly defined, which has made both recognition and management challenging. This review examines the previous definitions of IF as well as the newer definition and classification of IF and how it is essential to IF clinical guidelines.

  2. Seronegative Intestinal Villous Atrophy: A Diagnostic Challenge

    Directory of Open Access Journals (Sweden)

    Cláudio Martins

    2016-01-01

    Full Text Available Celiac disease is the most important cause of intestinal villous atrophy. Seronegative intestinal villous atrophy, including those that are nonresponsive to a gluten-free diet, is a diagnostic challenge. In these cases, before establishing the diagnosis of seronegative celiac disease, alternative etiologies of atrophic enteropathy should be considered. Recently, a new clinical entity responsible for seronegative villous atrophy was described—olmesartan-induced sprue-like enteropathy. Herein, we report two uncommon cases of atrophic enteropathy in patients with arterial hypertension under olmesartan, who presented with severe chronic diarrhea and significant involuntary weight loss. Further investigation revealed intestinal villous atrophy and intraepithelial lymphocytosis. Celiac disease and other causes of villous atrophy were ruled out. Drug-induced enteropathy was suspected and clinical improvement and histologic recovery were verified after olmesartan withdrawal. These cases highlight the importance for clinicians to maintain a high index of suspicion for olmesartan as a precipitant of sprue-like enteropathy.

  3. Intestinal infarction: A complication of endovascular therapy

    International Nuclear Information System (INIS)

    England, Andrew; Butterfield, John S.; Sukumar, Sathi; Thompson, David; Roulson, Jo-An; Pritchard, Susan; Ashleigh, Raymond J.

    2007-01-01

    This report presents a rare case of intestinal infarction following endovascular therapy. A female patient who had undergone an internal carotid artery stenting procedure presented suddenly with abdominal pain. Radiological and clinical examinations at the time suggested a picture of intestinal ischaemia, in view of the patient's general conditions and co-existing morbidities surgical intervention was not considered to be an option. The patient died 4 days after the carotid stenting procedure, post-mortem examination revealed infarction of the ileum and caecum. The learning outcomes are if performing endovascular therapy in a patient with diffuse atherosclerotic disease early consideration of intestinal ischaemia should be given to any patient who presents with acute post-procedural abdominal pain

  4. [Pneumatosis cystoides intestinalis complicated with intestinal volvulus].

    Science.gov (United States)

    Fuenmayor, Carmen Elena; Gainza, Carlos; García, Maryori; Zambrano, Richard; Torres, Gledys; Hernández, Yohanys; García, Anna

    2017-01-01

    Pneumatosis cystoides intestinalis is a rare condition in which multiple gas-filled cysts are found within the wall of the gastrointestinal tract either in the subserosa or submucosa. Its pathogenesis is uncertain and several pathogenic mechanisms have been proposed to explain its origin. The case of a male patient of 46 years with previous diagnosis of pneumatosis cystic intestinalis, who consulted for abdominal pain, vomiting and fever (39 °C) is presented. By the time of admission ther were signs of peritoneal irritation. The X-ray abdominal reported distension and intestinal hydro-air levels. Exploratory laparotomy was performed and revealed small bowel volvulus with strangulation of some intestinal segment. Histological diagnosis was pneumatosis cystic intestinalis complicated with Infarction trans-mural by intestinal volvulus. The patient evolved satisfactorily.

  5. Intestinal malrotation and catastrophic volvulus in infancy.

    Science.gov (United States)

    Lee, Henry Chong; Pickard, Sarah S; Sridhar, Sunita; Dutta, Sanjeev

    2012-07-01

    Intestinal malrotation in the newborn is usually diagnosed after signs of intestinal obstruction, such as bilious emesis, and corrected with the Ladd procedure. The objective of this report is to describe the presentation of severe cases of midgut volvulus presenting in infancy, and to discuss the characteristics of these cases. We performed a 7-year review at our institution and present two cases of catastrophic midgut volvulus presenting in the post-neonatal period, ending in death soon after the onset of symptoms. These two patients also had significant laboratory abnormalities compared to patients with more typical presentations resulting in favorable outcomes. Although most cases of intestinal malrotation in infancy can be treated successfully, in some circumstances, patients' symptoms may not be detected early enough for effective treatment, and therefore may result in catastrophic midgut volvulus and death. Copyright © 2012 Elsevier Inc. All rights reserved.

  6. Radiodiagnosis of early radiation intestinal changes

    International Nuclear Information System (INIS)

    Volodina, G.I.; Abdulkhakova, D.A.

    1987-01-01

    X-ray examination of the colon in 102 patients and of the small intestine in 62 was performed during combined radiation therapy of cervical cancer and at different time after its discontinuation. Early radiation functional and morphological changes in the ileum and colon were detected. Radiation changes in the ileac mucosa were noted in 52% of the patients, changes of various degree in the rectal, sigmoid and cecal mucosa were noted in 41.2%. Moderate radiation changes in the ascending, descending and horizontal parts of the colon were noted in 10.7%. Early radiation intestinal injuries in the form of erosions and ulcers were revealed in 5.8% of the patients. In most of the patients radiation intestinal changes were without noticeable clinical manifestations. All these patients could be defined as a group at risk of developing late radiation changes

  7. Small Bowel Obstruction due to Intestinal Xanthomatosis

    Directory of Open Access Journals (Sweden)

    L. E. Barrera-Herrera

    2015-01-01

    Full Text Available Vast majority of bowel obstruction is due to postoperative adhesions, malignancy, intestinal inflammatory disease, and hernias; however, knowledge of other uncommon causes is critical to establish a prompt treatment and decrease mortality. Xanthomatosis is produced by accumulation of cholesterol-rich foamy macrophages. Intestinal xanthomatosis is an uncommon nonneoplastic lesion that may cause small bowel obstruction and several cases have been reported in the English literature as obstruction in the jejunum. We report a case of small intestinal xanthomatosis occurring in a 51-year-old female who presented with one day of copious vomiting and intermittent abdominal pain. Radiologic images revealed jejunal loop thickening and inflammatory changes suggestive of foreign body obstruction, diagnostic laparoscopy found two strictures at the jejunum, and a pathologic examination confirmed a segmental small bowel xanthomatosis. This case illustrates that obstruction even without predisposing factors such as hyperlipidemia or lymphoproliferative disorders.

  8. Recent Advances in Intestinal Stem Cells.

    Science.gov (United States)

    McCabe, Laura R; Parameswaran, Narayanan

    2017-09-01

    The intestine is a dynamic organ with rapid stem cell division generating epithelial cells that mature and apoptose in 3-5 days. Rapid turnover maintains the epithelial barrier and homeostasis. Current insights on intestinal stem cells (ISCs) and their regulation are discussed here. The Lgr5+ ISCs maintain intestinal homeostasis by dividing asymmetrically, but also divide symmetrically to extinguish or replace ISCs. Following radiation or mucosal injury, reserve BMI1+ ISCs as well as other crypt cells can de-differentiate into Lgr5+ ISCs. ISC niche cells, including Paneth, immune and myofibroblast cells secrete factors that regulate ISC proliferation. Finally, several studies indicate that the microbiome metabolites regulate ISC growth. ISC cells can be plastic and integrate a complexity of environmental/niche cues to trigger or suppress proliferation as needed.

  9. Intestinal infarction: A complication of endovascular therapy

    Energy Technology Data Exchange (ETDEWEB)

    England, Andrew [Department of Radiology, South Manchester University Hospitals NHS Trust, Southmoor Road, Wythenshawe, Manchester M23 9LT (United Kingdom)]. E-mail: andrew.england@smtr.nhs.uk; Butterfield, John S. [Department of Radiology, South Manchester University Hospitals NHS Trust, Southmoor Road, Wythenshawe, Manchester M23 9LT (United Kingdom); Sukumar, Sathi [Department of Radiology, South Manchester University Hospitals NHS Trust, Southmoor Road, Wythenshawe, Manchester M23 9LT (United Kingdom); Thompson, David [Department of Radiology, South Manchester University Hospitals NHS Trust, Southmoor Road, Wythenshawe, Manchester M23 9LT (United Kingdom); Roulson, Jo-An [Department of Histopathology, South Manchester University Hospitals NHS Trust, Southmoor Road, Wythenshawe, Manchester M23 9LT (United Kingdom); Pritchard, Susan [Department of Histopathology, South Manchester University Hospitals NHS Trust, Southmoor Road, Wythenshawe, Manchester M23 9LT (United Kingdom); Ashleigh, Raymond J. [Department of Radiology, South Manchester University Hospitals NHS Trust, Southmoor Road, Wythenshawe, Manchester M23 9LT (United Kingdom)

    2007-08-15

    This report presents a rare case of intestinal infarction following endovascular therapy. A female patient who had undergone an internal carotid artery stenting procedure presented suddenly with abdominal pain. Radiological and clinical examinations at the time suggested a picture of intestinal ischaemia, in view of the patient's general conditions and co-existing morbidities surgical intervention was not considered to be an option. The patient died 4 days after the carotid stenting procedure, post-mortem examination revealed infarction of the ileum and caecum. The learning outcomes are if performing endovascular therapy in a patient with diffuse atherosclerotic disease early consideration of intestinal ischaemia should be given to any patient who presents with acute post-procedural abdominal pain.

  10. Intestinal Microbiota Signatures Associated With Histological Liver Steatosis in Pediatric-Onset Intestinal Failure.

    Science.gov (United States)

    Korpela, Katri; Mutanen, Annika; Salonen, Anne; Savilahti, Erkki; de Vos, Willem M; Pakarinen, Mikko P

    2017-02-01

    Intestinal failure (IF)-associated liver disease (IFALD) is the major cause of mortality in IF. The link between intestinal microbiota and IFALD is unclear. We compared intestinal microbiota of patients with IF (n = 23) with healthy controls (n = 58) using culture-independent phylogenetic microarray analysis. The microbiota was related to histological liver injury, fecal markers of intestinal inflammation, matrix metalloproteinase 9 and calprotectin, and disease characteristics. Overabundance of Lactobacilli, Proteobacteria, and Actinobacteria was observed in IF, whereas bacteria related to Clostridium clusters III, IV, and XIVa along with overall diversity and richness were reduced. Patients were segregated into 3 subgroups based on dominating bacteria: Clostridium cluster XIVa, Proteobacteria, and bacteria related to Lactobacillus plantarum. In addition to liver steatosis and fibrosis, Proteobacteria were associated with prolonged current parenteral nutrition (PN) as well as liver and intestinal inflammation. Lactobacilli were related to advanced steatosis and fibrosis mostly after weaning off PN without associated inflammation. In multivariate permutational analysis of variance, liver steatosis, bowel length, PN calories, and antibiotic treatment best explained the microbiota variation among patients with IF. Intestinal microbiota composition was associated with liver steatosis in IF and better predicted steatosis than duration of PN or length of the remaining intestine. Our results may be explained by a model in which steatosis is initiated during PN in response to proinflammatory lipopolysaccharides produced by Proteobacteria and progresses after weaning off PN, as the L plantarum group Lactobacilli becomes dominant and affects lipid metabolism by altering bile acid signaling.

  11. The effect of fucoidan on intestinal flora and intestinal barrier function in rats with breast cancer.

    Science.gov (United States)

    Xue, Meilan; Ji, Xinqiang; Liang, Hui; Liu, Ying; Wang, Bing; Sun, Lingling; Li, Weiwei

    2018-02-21

    Recent research studies have shown that the intestinal flora are related to the occurrence and progress of breast cancer. This study investigates the effect of fucoidan on intestinal flora and intestinal barrier function in rats with 7,12-dimethylbenz[a]anthracene (DMBA)-induced breast cancers. Sixty female Sprague-Dawley rats were randomly assigned to the control group, the model group, and the F1 and F2 groups, which were fed fucoidan at concentrations of 200 and 400 mg per kg bw (body weight), respectively. Intestinal histopathological analysis was performed and 16S rDNA high-throughput sequencing was used to provide an overview of the intestinal flora composition. The contents of d-lactic acid (d-LA), diamine oxidase (DAO) and endotoxin in plasma were detected by ELISA. Expression levels of the tight junction (TJ) proteins, phosphorylated p38 MAPK and ERK1/2 were measured using western blotting. Our results suggested that the intestinal wall of the model group was damaged. However, after fucoidan intervention, the villi were gradually restored. ELISA showed that the levels of plasma endotoxin, d-LA and DAO decreased in the F1 and F2 groups compared to those in the model group. Fucoidan treatment also increased the expressions of ZO-1, occludin, claudin-1 and claudin-8. Furthermore, the expression levels of phosphorylated p38 MAPK and ERK1/2 were upregulated in fucoidan treatment groups. The results of 16S rDNA high-throughput sequencing indicated that fucoidan increased the diversity of the intestinal microbiota and induced changes in microbial composition, with the increased Bacteroidetes/Firmicutes phylum ratio. In conclusion, the supplement of fucoidan could improve the fecal microbiota composition and repair the intestinal barrier function. The study suggested the use of fucoidan as an intestinal flora modulator for potential prevention of breast cancer.

  12. Surface staining of small intestinal biopsies

    DEFF Research Database (Denmark)

    Poulsen, Steen Seier

    1977-01-01

    Small intestinal biopsies are most often by routine examined under a stereo-microscope, prior to embedding for histological examination. This is done in order to get a view of the appearance of the mucosal pattern, especially villus configuration. The distinctness of the surface pattern however......, is improved considerably if the biopsies are stained with Alcian Green and/or PAS before they are examined. In the present paper a detailed description is given of staining of small intestinal biopsies as whole mounts. The difference between the unstained and the stained biopsies is illustrated by a few...

  13. Translational control of an intestinal microvillar enzyme

    DEFF Research Database (Denmark)

    Danielsen, E M; Cowell, G M; Sjöström, H

    1986-01-01

    The rates of biosynthesis of adult and foetal pig small-intestinal aminopeptidase N (EC 3.4.11.2) were compared to determine at which level the expression of the microvillar enzyme is developmentally controlled. In organ-cultured explants, the rate of biosynthesis of foetal aminopeptidase N is only...... about 3% of the adult rate. The small amount synthesized occurs in a high-mannose-glycosylated, membrane-bound, form that is processed to the mature, complex-glycosylated, form at a markedly slower rate than that of the adult enzyme. Extracts of total RNA from adult and foetal intestine contained...

  14. Persistently increased intestinal fraction of alkaline phosphatase

    DEFF Research Database (Denmark)

    Nathan, E; Baatrup, G; Berg, H

    1984-01-01

    Persistent elevation of the intestinal fraction of the alkaline phosphatase (API) as an isolated finding has to our knowledge not been reported previously. It was found in a boy followed during a period of 5.5 years. The only symptom was transient periodic fatigue observed at home, but not apparent...... during hospitalization. His blood type was O, RH+, Le (a-, b+) and he was a secretor of H-substance, which may be associated with rising API activity after fat-loading. In this case API was unchanged after fat-loading. Neither intestinal nor liver diseases were found, and no other cause for the elevated...

  15. Intestinal lymphangiectasia secondary to radiotherapy and chemotherapy

    International Nuclear Information System (INIS)

    Rao, S.S.; Dundas, S.; Holdsworth, C.D.

    1987-01-01

    We report a case of intestinal lymphangiectasia secondary to radiotherapy and chemotherapy. The patient also had small bowel bacterial overgrowth and pancreatic insufficiency. Lymphatic ectasia as a histological feature has been described previously in association with postradiotherapy malabsorption, but radiation-induced lymphangiectasia producing clinical manifestations has hitherto not been reported. Replacement of dietary long-chain fats with medium-chain triglycerides, pancreatic enzyme supplements, and a short course of oxytetracycline, resulted in dramatic clinical improvement. The possibility of intestinal lymphangiectasia should be borne in mind in patients with postradiotherapy malabsorption. A low serum albumin and lymphocyte count should draw attention to this possibility

  16. Intestinal Rotation Abnormalities and Midgut Volvulus.

    Science.gov (United States)

    Langer, Jacob C

    2017-02-01

    Rotation abnormalities may be asymptomatic or may be associated with obstruction caused by bands, midgut volvulus, or associated atresia or web. The most important goal of clinicians is to determine whether the patient has midgut volvulus with intestinal ischemia, in which case an emergency laparotomy should be done. If the patient is not acutely ill, the next goal is to determine whether the patient has a narrow-based small bowel mesentery. In general, the outcomes for children with a rotation abnormality are excellent, unless there has been midgut volvulus with significant intestinal ischemia. Copyright © 2016 Elsevier Inc. All rights reserved.

  17. Relationships between intestinal parasitosis and handedness.

    Science.gov (United States)

    Uslu, Hakan; Dane, Senol; Uyanik, M Hamidullah; Ayyildiz, Ahmet

    2010-07-01

    The aim of the study was to investigate if there is a possible relation between intestinal parasitosis and handedness in patients with suspected intestinal parasitosis. Hand preference was assessed on the Edinburgh Handedness Inventory. Stool samples were examined microscopically for the presence of parasite. In the present study right-handers had many more helminth infections and left-handers had many more protozoon infections. Lower rate of helminth infections in the present study, and higher asthma incidences in the left-handed population in literature, may be associated with different immune machinery in left-handed people than in right-handed ones.

  18. Modelación matemática del proceso de lixiviación ácida de las colas del proceso Caron

    Directory of Open Access Journals (Sweden)

    Lianis de los Ángeles Columbié-Lamorú

    2013-12-01

    Full Text Available Se modeló matemáticamente la extracción de cobalto a escala de laboratorio mediante lixiviación ácida de colas negras del proceso Caron. La modelación partió de las ecuaciones del balance de materia y energía ajustadas al proceso ensayado, con el fin de tomar decisiones respecto a los parámetros usados para la lixiviación (temperatura, concentración inicial de ácido sulfúrico y concentración del agente reductor, sulfato de hierro II. Como resultado se obtuvo un modelo, formado por ocho ecuaciones, que describe el comportamiento dinámico del proceso de extracción de cobalto, por vía ácida, de colas negras amoniacales; el modelo permite calcular apropiadamente los parámetros de la lixiviación y monitorear la influencia de estos en la extracción de cobalto como indicador de marcha del proceso

  19. Aplasia cutis congenita, skull defect, brain heterotopia, and intestinal lymphangiectasia

    NARCIS (Netherlands)

    Bonioli, Eugenio; Hennekam, Raoul C.; Spena, Gianantonio; Morcaldi, Guido; Di Stefano, Antonio; Serra, Giovanni; Bellini, Carlo

    2005-01-01

    We describe a female infant with a previously unreported combination of manifestations characterized by aplasia cutis, skull defect, brain heterotopia, mild congenital lymphedema, and intestinal lymphangiectasia. The association of intestinal lymphangiectasia and aplasia cutis, and the association

  20. Morphological development of the small intestine in White Roman ...

    African Journals Online (AJOL)

    Customer

    2013-02-06

    Feb 6, 2013 ... intestine using the light microscope and scanning electron microscope in order to ... in morphology and structure of small intestinal segments in geese from ... in the multi-regression model (Steel and Torrie, 1960). RESULTS.

  1. Starved Guts: Morphologic and Functional Intestinal Changes in Malnutrition.

    Science.gov (United States)

    Attia, Suzanna; Feenstra, Marjon; Swain, Nathan; Cuesta, Melina; Bandsma, Robert H J

    2017-11-01

    Malnutrition contributes significantly to death and illness worldwide and especially to the deaths of children younger than 5 years. The relation between intestinal changes in malnutrition and morbidity and mortality has not been well characterized; however, recent research indicates that the functional and morphologic changes of the intestine secondary to malnutrition itself contribute significantly to these negative clinical outcomes and may be potent targets of intervention. The aim of this review was to summarize current knowledge of experimental and clinically observed changes in the intestine from malnutrition preclinical models and human studies. Limited clinical studies have shown villous blunting, intestinal inflammation, and changes in the intestinal microbiome of malnourished children. In addition to these findings, experimental data using various animal models of malnutrition have found evidence of increased intestinal permeability, upregulated intestinal inflammation, and loss of goblet cells. More mechanistic studies are urgently needed to improve our understanding of malnutrition-related intestinal dysfunction and to identify potential novel targets for intervention.

  2. Typhoid Intestinal Perforation: 24 Perforations in One Patient

    African Journals Online (AJOL)

    Intestinal perforation is a common cause of peritonitis necessitating emergency surgical intervention. Perforation ... Mortality rates of typhoid intestinal perforation (TIP) cases are ... may be obscured clinical features with resultant delays in.

  3. Case series of unusual causes intestinal obstruction in infants and ...

    African Journals Online (AJOL)

    Introduction Many of the causes of intestinal obstruction arise from ... In this work, we report eight unusual cases of intestinal ..... lymph is considered to be the result of an imbalance ... During fetal life, midgut communicates with the yolk sac.

  4. Diversity of human small intestinal Streptococcus and Veillonella populations

    NARCIS (Netherlands)

    van den Bogert, Bartholomeus; Erkus, Oylum; Boekhorst, Jos; de Goffau, Marcus; Smid, Eddy J.; Zoetendal, Erwin G.; Kleerebezem, Michiel

    Molecular and cultivation approaches were employed to study the phylogenetic richness and temporal dynamics of Streptococcus and Veillonella populations in the small intestine. Microbial profiling of human small intestinal samples collected from four ileostomy subjects at four time points displayed

  5. Intestinal sclerosis with pseudo-obstruction in three dogs.

    Science.gov (United States)

    Moore, R; Carpenter, J

    1984-04-01

    Intestinal sclerosis causing chronic intestinal pseudo-obstruction was diagnosed in 3 dogs. The pseudo-obstruction was characterized by vomiting and weight loss of 2 weeks' to 3 months' duration. A patent intestinal lumen was determined by contrast radiography and verified at surgery. Intestinal biopsy revealed diffuse atrophy, fibrosis, and mononuclear cell infiltration of the tunica muscularis. Each dog was euthanatized because of a progressive, deteriorating clinical course.

  6. DE LA FORMACIÓN DE GRUPOS A EQUIPOS DE TRABAJO DOCENTE MEDIANTE PROCESOS DE COMUNICACIÓN PERSONAL. APUNTES SOBRE LA CONCEPCION METODOLOGICA DEL PROCESO.

    Directory of Open Access Journals (Sweden)

    María de los Angeles Linares Borrell

    2008-06-01

    Full Text Available La formación de equipos de trabajo es un imperativo del mundo actual, ya se trate de la actividad empresarial, o de la administración pública. La Educación Superior que cada vez mas trasciende su funcionamiento interno y los procesos de enseñanza aprendizaje, a la actividad extramuros tiene que lograr estas nuevas formas de trabajo en cada acción académica que realice. Para lograr la formación de profesionales comprometidos con la sociedad se requiere la participación y la interacción de todos y esto sólo puede lograrse generando el cambio de los grupos formales a equipos de trabajo, lo que es válido para cualquier sector de la sociedad y tiene en la comunicación un eje transversal imprescindible. El fundamento teórico del proceso lo constituyen la ingeniería de formación en dirección y el método de interacción a través de las técnicas de discusión por desarrollo, como enfoque básico de comunicación. Una experiencia de diez días de intensa actividad interactiva, creando espacios de comunicación formal e informal en un proceso docente demostró que entre todos puede lograrse el enfoque educativo mediante la comunicación, que contiene: la educación como proceso de diálogo y transformación, basada en el privilegio de lo colectivo, la creatividad, la interacción e interdependencia, la contextualización, la interdisciplinariedad, generando salidas de proceso con elevada calidad y acorde a las necesidades de cada sociedad específica.

  7. Intestinal candidiasis and antibiotic usage in children: case study of ...

    African Journals Online (AJOL)

    Conclusion: The results of this study showed a high prevalence of intestinal candidiasis among children in Nsukka. Strong associations were observed between the presence of intestinal candidiasis and diarrhoea, age and use of antibiotics (p<0.001). Keywords: Intestinal candidiasis, children, antibiotic use, diarrhea ...

  8. Community and genomic analysis of the human small intestine microbiota

    NARCIS (Netherlands)

    Bogert, van den B.

    2013-01-01

    Our intestinal tract is densely populated by different microbes, collectively called microbiota, of which the majority are bacteria. Research focusing on the intestinal microbiota often use fecal samples as a representative of the bacteria that inhabit the end of the large intestine.

  9. Risks of intestinal helminthiasis in children living in orphanages in ...

    African Journals Online (AJOL)

    Risks of intestinal helminthiasis in children living in orphanages in Benin city, Nigeria. ... of intestinal helminthiasis (p = 0.016). Conclusion: Behavioural modification, good personal hygiene and provision of towels for each child living in the orphanage should be integral part of intestinal helminths control in orphanages.

  10. The small intestine microbiota, nutritional modulation and relevance for health

    NARCIS (Netherlands)

    El Aidy, Sahar; van den Bogert, Bartholomeus; Kleerebezem, Michiel

    The intestinal microbiota plays a profound role in human health and extensive research has been dedicated to identify microbiota aberrations that are associated with disease. Most of this work has been targeting the large intestine and fecal microbiota, while the small intestine microbiota may also

  11. Protective effect of salvianolic acid B against intestinal ischemia ...

    African Journals Online (AJOL)

    Conclusion: The results of this study demonstrate that SAB may protect the intestine by attenuating oxidative stress and inflammatory response and hence, may be potentially for treating IIRI. Keywords: Salvianolic acid B, Intestinal Ischemia-reperfusion, Antioxidants, Inflammation, Intestinal permeability ...

  12. burden of intestinal parasites amongst hiv/aids patients attending

    African Journals Online (AJOL)

    boaz

    ABSTRACT. Background: Intestinal parasitic infections cause severe diarrhea especially in debilitated subjects with clinical ... Regional Hospital, Entamoeba histolytica and other intestinal parasites represented a common burden. .... Attempt was made to go through all the fields of ..... Control of Intestinal parasite Infections.

  13. Thyroid hormone regulation of adult intestinal stem cells: Implications on intestinal development and homeostasis.

    Science.gov (United States)

    Sun, Guihong; Roediger, Julia; Shi, Yun-Bo

    2016-12-01

    Organ-specific adult stem cells are essential for organ homeostasis, tissue repair and regeneration. The formation of such stem cells often takes place during postembryonic development, a period around birth in mammals when plasma thyroid hormone concentration is high. The life-long self-renewal of the intestinal epithelium has made mammalian intestine a valuable model to study the function and regulation and adult stem cells. On the other hand, much less is known about how the adult intestinal stem cells are formed during vertebrate development. Here, we will review some recent progresses on this subject, focusing mainly on the formation of the adult intestine during Xenopus metamorphosis. We will discuss the role of thyroid hormone signaling pathway in the process and potential molecular conservations between amphibians and mammals as well as the implications in organ homeostasis and human diseases.

  14. Intestinal obstruction secondary to infantile polyarteritis nodosa ...

    African Journals Online (AJOL)

    Polyarteritis Nodosa (PAN) is a rare systemic necrotising vasculitis of medium and small-sized arteries. Patients typically present with systemic symptoms. Obstructive intestinal symptoms are described but usually resolve with treatment of the underlying vascular disease. We report a case of a one year old boy with multiple ...

  15. Peritoneal drainage for newborn intestinal perforation: primary ...

    African Journals Online (AJOL)

    Keywords: intestinal perforation in newborn, necrotizing enterocolitis, primary peritoneal drainage. Department of Surgery, Paul L. Foster School of Medicine, Texas Tech University. HSC, El Paso, Texas, USA. Correspondence to Donald E. Meier, MD, Department of Surgery, Paul L. Foster. School of Medicine, Texas Tech ...

  16. Performance, Nutrient Utilization and Intestinal Environment of ...

    African Journals Online (AJOL)

    The performance, nutrient utilization and intestinal environment of weaned rabbits fed diets supplemented with organic acids (acetic acid, citric acid and formic acid) were investigated with 24 (6-week old) rabbits in a completely randomized design. The control diet was not supplemented while others were supplemented ...

  17. Intestinal tuberculosis presenting as acute abdomen

    International Nuclear Information System (INIS)

    Khan, M.A.; Majeed, F.A.; Ahmed, M.; Khan, M.N.

    2012-01-01

    Objectives: To study the outcome of intestinal tuberculosis presenting as acute abdomen. Study design: Descriptive Study. Place and Duration: Bolan Medical Complex Hospital (BMC) Quetta and Combined Military Hospital (CMH) Quetta from Nov 2003 to Nov 2005 from Bolan Medical Complex and from Nov 2005 to Nov 2006 in CMH Quetta. Material and Method: Thirty seven patients of acute abdomen presenting with intestinal obstruction were admitted; 28 from emergency department and 9 from out patient department. Twenty seven patients were from BMC and 10 from CMH Quetta. Patients were diagnosed as having abdominal tuberculosis on the basis of operative findings and histopathological reports. Results: Out of 37 patients presenting with acute abdomen due to intestinal obstruction, 54% were male and 46% were female with M: F ratio of 1: 1.2. Age of the patient ranged from 20 to 50 years, with maximum frequency between 30 to 40 years. Abdominal pain was the commonest presenting feature in all patients followed by constipation in 81.1% patients. Peritonism was seen in 27% patients. Different operative procedures performed were adhesionolysis 65.8%, segmental resection 7.9%, right hemicolectomy 10.5%, stricturoplasty 7.9% and ileostomy 1.3%. Mesenteric lymph node biopsy 40.8%. Conclusion: Intestinal tuberculosis is still a very important surgical problem in our country presenting as acute abdomen. A suspicion must always be kept during laparotomy and adequate tissue histopathology should supplement the diagnosis. (author)

  18. Knowledge based assessment of intestinal parasitic Infections ...

    African Journals Online (AJOL)

    There is an apparent lack of information on the risk and clinical symptoms of Intestinal Parasitic Infections (IPIs) among students attending boarding secondary schools in Ebonyi State, Nigeria. This questionnaire-based survey attempts to assess some behavioural habits, possible risk factor(s) as well as clinical symptoms ...

  19. characterization of intestinal microbiota in celiac children

    African Journals Online (AJOL)

    F. Lahcene1*, A. Tir Touil Meddah1, K. Bouziane-Nedjadi2, B. Meddah1, A. Leke3

    2016-09-01

    Sep 1, 2016 ... In this study, 13 Samples of intestinal biopsy, ... Research Article. Journal of Fundamental and Applied Sciences is licensed under a Creative Commons Attribution-NonCommercial 4.0. International License. ... disease are caused by several factors among, the ingestion of gluten, and it has been suggested.

  20. Postoperative Adhesive Intestinal Obstruction from Gossypiboma ...

    African Journals Online (AJOL)

    We report a case of 41.year.old female admitted with features of intestinal obstruction and had a previous history of hysterectomy performed 2 months back at another hospital. Pathologists must be aware of this entity and its proper reporting as the cases are liable to go to court. Surgeons must recognize the risk factors that ...

  1. Temporary intestinal ischemia for radiation protection

    International Nuclear Information System (INIS)

    Lote, K.

    1983-01-01

    The most important determinant of cellular radiosensivity is the tissue oxygen content at the time of irradiation. The purpose of the present experimental work was to assess a new iscemia-inducing method in order to reduce normal tissue radiation damage during radiotherapy. Temporary ischemia was induced in a cat small intestine by degraded starch microspheres. Regional arterial and tissue blod flow immediately fell by 85% with subsequent normalization within 26 minutes after microsphere injection. No tendency of small vessel thrombosis caused by starch sphere embolization in combination with previous or current intestinal irradiation was detected. Starch sphere remenants were rapidly engulfed by, and persisted within tissue macrophages for 14 days without causing intestinal inflammatory reactions. In vitro studies showed that human platelets neither adhered to nor were aggregated by starch microspheres. The new method, wich occlude arteriolar vessels distal to the mesentric arterial arcades and thus largely excludes collateral blood flow, seems suited to provide effictive and selective feline small intestinal hypoxic radiation protection. This conclusion may also be valid in man

  2. Metabolic complications in the small intestine syndrome

    International Nuclear Information System (INIS)

    Mora, Rafael; Orozco, Reynaldo

    2000-01-01

    Metabolic complications in the syndrome of small intestine is presented in a patient of masculine sex, 27 years old, who consulted for a square of inflammation gingival, migraine, fever, anorexia and adinamia for three days, followed by maculopapular-eritematose eruption for 8 days, coincident with the ampicillin ingestion, and later on severe abdominal pain and diarrhea

  3. Lymphoid cells in chicken intestinal epithelium

    DEFF Research Database (Denmark)

    Bjerregaard, P

    1975-01-01

    The intraepithelial lymphoid cells of chicken small intestine were studied by light microscopy using 1 mu Epon sections, and by electron microscopy. Three cell types were found: small lymphocytes, large lymphoid cells, and granular cells. These cells correspond to the theliolymphocytes and globule...

  4. Intestinal inflammatory myofibroblastic tumour | Ntloko | South ...

    African Journals Online (AJOL)

    Conclusions. Surgery with tumour-free resection margins is the gold standard of care of adult and paediatric I-IMFTs. Heightened recognition of I-IMFT, albeit rare, as a cause of intestinal obstruction, including intussusception, is necessary for preoperative suspicion of I-IMFT. SAJS, VOL 49, NO. 4, NOVEMBER 2011 ...

  5. Childhood malnutrition and the intestinal microbiome.

    Science.gov (United States)

    Kane, Anne V; Dinh, Duy M; Ward, Honorine D

    2015-01-01

    Malnutrition contributes to almost half of all deaths in children under the age of 5 y, particularly those who live in resource-constrained areas. Those who survive frequently suffer from long-term sequelae including growth failure and neurodevelopmental impairment. Malnutrition is part of a vicious cycle of impaired immunity, recurrent infections, and worsening malnutrition. Recently, alterations in the gut microbiome have also been strongly implicated in childhood malnutrition. It has been suggested that malnutrition may delay the normal development of the gut microbiota in early childhood or force it toward an altered composition that lacks the required functions for healthy growth and/or increases the risk for intestinal inflammation. This review addresses our current understanding of the beneficial contributions of gut microbiota to human nutrition (and conversely the potential role of changes in that community to malnutrition), the process of acquiring an intestinal microbiome, potential influences of malnutrition on the developing microbiota, and the evidence directly linking alterations in the intestinal microbiome to childhood malnutrition. We review recent studies on the association between alterations in the intestinal microbiome and early childhood malnutrition and discuss them in the context of implications for intervention or prevention of the devastation caused by malnutrition.

  6. Genetics Home Reference: intestinal pseudo-obstruction

    Science.gov (United States)

    ... A characteristic of X-linked inheritance is that fathers cannot pass X-linked traits to their sons. Intestinal pseudo-obstruction caused by ACTG2 gene mutations is inherited in an autosomal dominant pattern , which means one copy of the altered ...

  7. Pig models on intestinal development and therapeutics.

    Science.gov (United States)

    Yin, Lanmei; Yang, Huansheng; Li, Jianzhong; Li, Yali; Ding, Xueqing; Wu, Guoyao; Yin, Yulong

    2017-12-01

    The gastrointestinal tract plays a vital role in nutrient supply, digestion, and absorption, and has a crucial impact on the entire organism. Much attention is being paid to utilize animal models to study the pathogenesis of gastrointestinal diseases in response to intestinal development and health. The piglet has a body size similar to that of the human and is an omnivorous animal with comparable anatomy, nutritional requirements, and digestive and associated inflammatory processes, and displays similarities to the human intestinal microbial ecosystem, which make piglets more appropriate as an animal model for human than other non-primate animals. Therefore, the objective of this review is to summarize key attributes of the piglet model with which to study human intestinal development and intestinal health through probing into the etiology of several gastrointestinal diseases, thus providing a theoretical and hopefully practical, basis for further studies on mammalian nutrition, health, and disease, and therapeutics. Given the comparable nutritional requirements and strikingly similar brain developmental patterns between young piglets and humans, the piglet has been used as an important translational model for studying neurodevelopmental outcomes influenced by pediatric nutrition. Because of similarities in anatomy and physiology between pigs and mankind, more emphasises are put on how to use the piglet model for human organ transplantation research.

  8. Behavioural actions of vasoactive intestinal peptide (VIP)

    NARCIS (Netherlands)

    Kloet, E.R.; Cottrell, G.A.; Veldhuis, H.D.; Rostene, W.H.

    1984-01-01

    The effect of vasoactive intestinal peptide (VIP) was studied on fear-motivated behaviours, exploration of a novel environment and on novelty and ACTH-induced grooming. VIP was administered via a plastic cannula into the lateral ventricle. Retention of a step-through passive avoidance task was

  9. Intestinal perforation caused by multiple magnet ingestion

    Directory of Open Access Journals (Sweden)

    Nergul Corduk

    2014-01-01

    Full Text Available Multiple magnet ingestion is rare, but can cause serious gastrointestinal complications. We report a case of 7-year-old girl with multiple intestinal perforations caused by multiple magnet ingestion. The aim of this report is to draw attention to magnetic toys, results of magnet ingestion and the importance of timing of operation.

  10. Compartmentalization of Aquaporins in the Human Intestine

    Directory of Open Access Journals (Sweden)

    Rajendram V. Rajnarayanan

    2008-06-01

    Full Text Available Improper localization of water channel proteins called aquaporins (AQP induce mucosal injury which is implicated in Crohn’s disease and ulcerative colitis. The amino acid sequences of AQP3 and AQP10 are 79% similar and belong to the mammalian aquaglyceroporin subfamily. AQP10 is localized on the apical compartment of the intestinal epithelium called the glycocalyx while AQP3 is selectively targeted to the basolateral membrane. Despite the high sequence similarity and evolutionary relatedness, the molecular mechanism involved in the polarity, selective targeting and function of AQP3 and AQP10 in the intestine is largely unknown. Our hypothesis is that the differential polarity and selective targeting of AQP3 and AQP10 in the intestinal epithelial cells is influenced by amino acid signal motifs. We performed sequence and structural alignments to determine differences in signals for localization and posttranslational glycosylation. The basolateral sorting motif “YRLL” is present in AQP3 but absent in AQP10; while Nglycosylation signals are present in AQP10 but absent in AQP3. Furthermore, the C-terminal region of AQP3 is longer compared to AQP10. The sequence and structural differences between AQP3 and AQP10 provide insights into the differential compartmentalization and function of these two aquaporins commonly expressed in human intestines.

  11. Unusual cause of neonatal intestinal obstruction | Zikavska ...

    African Journals Online (AJOL)

    There are many causes of intestinal obstruction in the neonatal age. The most common types are mechanical and result from congenital malformations of the gastrointestinal tract. However, functional disorders also occur. In some cases, diagnosis can be made prenatally but in others manifestation occurs after birth. The aim ...

  12. Intestinal helminth infections among pregnant Cameroonian women ...

    African Journals Online (AJOL)

    Objectives: To investigate the prevalence and intensity of intestinal helminth infections in pregnant Cameroonian women and assess their anaemic status. Design: Longitudinal study. Setting: Buea Integrated Health Centre, Muea Health Centre, Mutengene Integrated Health Centre and the University of Buea Life Sciences ...

  13. Transcriptome changes during intestinal cell differentiation

    DEFF Research Database (Denmark)

    Tadjali, Mehrdad; Seidelin, Jakob B; Olsen, Jørgen Lillelund

    2002-01-01

    The expression of 18149 genes have been analysed during the differentiation of the human intestinal cell line Caco-2. cDNA probes from undifferentiated and differentiated Caco-2 cells were separately hybridised to EST DNAs spotted in an array on a nylon membrane. A remarkable change in the transc...

  14. Mucin dynamics in intestinal bacterial infection.

    Directory of Open Access Journals (Sweden)

    Sara K Lindén

    Full Text Available Bacterial gastroenteritis causes morbidity and mortality in humans worldwide. Murine Citrobacter rodentium infection is a model for gastroenteritis caused by the human pathogens enteropathogenic Escherichia coli and enterohaemorrhagic E. coli. Mucin glycoproteins are the main component of the first barrier that bacteria encounter in the intestinal tract.Using Immunohistochemistry, we investigated intestinal expression of mucins (Alcian blue/PAS, Muc1, Muc2, Muc4, Muc5AC, Muc13 and Muc3/17 in healthy and C. rodentium infected mice. The majority of the C. rodentium infected mice developed systemic infection and colitis in the mid and distal colon by day 12. C. rodentium bound to the major secreted mucin, Muc2, in vitro, and high numbers of bacteria were found in secreted MUC2 in infected animals in vivo, indicating that mucins may limit bacterial access to the epithelial surface. In the small intestine, caecum and proximal colon, the mucin expression was similar in infected and non-infected animals. In the distal colonic epithelium, all secreted and cell surface mucins decreased with the exception of the Muc1 cell surface mucin which increased after infection (p<0.05. Similarly, during human infection Salmonella St Paul, Campylobacter jejuni and Clostridium difficile induced MUC1 in the colon.Major changes in both the cell-surface and secreted mucins occur in response to intestinal infection.

  15. Intestinal obstruction in germ-free dogs.

    Science.gov (United States)

    Heneghan, J B; Robinson, J W; Menge, H; Winistörfer, B

    1981-08-01

    Mechanical occlusions were created in the intestines of four germ-free dogs. At the time of the operation, a control loop of mid-intestine was perfused in vivo and then excised for examinations in vitro, which included the determination of the equilibrium uptake of phenylalanine and of beta-methyl-glucoside, the influx kinetics of phenylalanine and morphometric analysis of the mucosa by microdissection and stereological techniques. Seven days after establishment of the occlusion the abdomen was reopened, and loops above and below the occlusion were perfused, and then excised for the same tests in vitro. Unlike occluded loops of conventional dogs, the intestine of the germ-free animal above the occlusion does not secrete water and electrolytes into the lumen. Its transport properties in vitro do not differ from those of the control loop, and the morphometric analyses reveal only slight changes in villus structure. The loop below the obstruction undergoes marked atrophy, as has been observed in conventional dogs. The results suggest that the copious secretion that occurs above an intestinal obstruction in normal animals is due to the presence of an abundant bacterial population in the obstruction fluid.

  16. Intestinal endocrine cells in radiation enteritis

    NARCIS (Netherlands)

    Pietroletti, R.; Blaauwgeers, J. L.; Taat, C. W.; Simi, M.; Brummelkamp, W. H.; Becker, A. E.

    1989-01-01

    In this study, the intestinal endocrine cells were investigated in 13 surgical specimens affected by radiation enteritis. Endocrine cells were studied by means of Grimelius' silver staining and immunostaining for chromogranin, a general marker of endocrine cells. Positively stained cells were

  17. Faecalibacterium prausnitzii and human intestinal health

    NARCIS (Netherlands)

    Miquel, S.; Martin, R.; Rossi, O.; Bermudez-Humaran, L.G.; Chatel, J.M.; Sokol, H.; Thomas, M.; Wells, J.M.; Langella, P.

    2013-01-01

    Faecalibacterium prausnitzii is the most abundant bacterium in the human intestinal microbiota of healthy adults, representing more than 5% of the total bacterial population. Over the past five years, an increasing number of studies have clearly described the importance of this highly metabolically

  18. Intestinal colonisation, microbiota and future probiotics

    NARCIS (Netherlands)

    Salminen, S.; Benno, Y.; Vos, de W.M.

    2006-01-01

    The human intestine is colonized by a large number of microorganisms, collectively termed microbiota, which support a variety of physiological functions. As the major part of the microbiota has not yet been cultured, molecular methods are required to determine microbial composition and the impact of

  19. Repairing organs : lessons from intestine and liver

    NARCIS (Netherlands)

    Gehart, Helmuth; Clevers, Hans

    2015-01-01

    The concept of organ regeneration has fascinated humanity from ancient mythology to modern science fiction. Recent advances offer the potential to soon bring such technology within the grasp of clinical medicine. Rapidly expanding insights into the intrinsic repair processes of the intestine and

  20. Intestinal Giardiasis Disguised as Ulcerative Colitis

    Directory of Open Access Journals (Sweden)

    Yu Zhen

    2018-01-01

    Full Text Available Parasite-associated colitis is quite rare in clinical practice of Ulcerative Colitis (UC. Here we reported an intestinal giardiasis case that has been diagnosed with UC. Further examination of stool revealed cysts of Giardia. This case completely responded to Albendazole. Giardiasis should be included for the differential diagnosis of UC.

  1. Repairing organs : lessons from intestine and liver

    NARCIS (Netherlands)

    Gehart, Helmuth; Clevers, Hans

    The concept of organ regeneration has fascinated humanity from ancient mythology to modern science fiction. Recent advances offer the potential to soon bring such technology within the grasp of clinical medicine. Rapidly expanding insights into the intrinsic repair processes of the intestine and

  2. Very late onset small intestinal B cell lymphoma associated with primary intestinal lymphangiectasia and diffuse cutaneous warts

    OpenAIRE

    Bouhnik, Y; Etienney, I; Nemeth, J; Thevenot, T; Lavergne-Slove, A; Matuchansky, C

    2000-01-01

    As only a handful of lymphoma cases have been reported in conjunction with primary intestinal lymphangiectasia, it is not yet clear if this association is merely fortuitous or related to primary intestinal lymphangiectasia induced immune deficiency. We report on two female patients, 50 and 58 years old, who developed small intestinal high grade B cell lymphoma a long time (45 and 40 years, respectively) after the initial clinical manifestations of primary intestinal lymphangiectasia. They pre...

  3. Fish oil enhances recovery of intestinal microbiota and epithelial integrity in chronic rejection of intestinal transplant.

    Directory of Open Access Journals (Sweden)

    Qiurong Li

    Full Text Available BACKGROUND: The intestinal chronic rejection (CR is the major limitation to long-term survival of transplanted organs. This study aimed to investigate the interaction between intestinal microbiota and epithelial integrity in chronic rejection of intestinal transplantation, and to find out whether fish oil enhances recovery of intestinal microbiota and epithelial integrity. METHODS/PRINCIPAL FINDINGS: The luminal and mucosal microbiota composition of CR rats were characterized by DGGE analysis at 190 days after intestinal transplant. The specific bacterial species were determined by sequence analysis. Furthermore, changes in the localization of intestinal TJ proteins were examined by immunofluorescent staining. PCR-DGGE analysis revealed that gut microbiota in CR rats had a shift towards Escherichia coli, Bacteroides spp and Clostridium spp and a decrease in the abundance of Lactobacillales bacteria in the intestines. Fish oil supplementation could enhance the recovery of gut microbiota, showing a significant decrease of gut bacterial proportions of E. coli and Bacteroides spp and an increase of Lactobacillales spp. In addition, CR rats showed pronounced alteration of tight junction, depicted by marked changes in epithelial cell ultrastructure and redistribution of occuldin and claudins as well as disruption in TJ barrier function. Fish oil administration ameliorated disruption of epithelial integrity in CR, which was associated with an improvement of the mucosal structure leading to improved tight junctions. CONCLUSIONS/SIGNIFICANCE: Our study have presented novel evidence that fish oil is involved in the maintenance of epithelial TJ integrity and recovery of gut microbiota, which may have therapeutic potential against CR in intestinal transplantation.

  4. Effects of Digested Onion Extracts on Intestinal Gene Expression: An Interspecies Comparison Using Different Intestine Models.

    Directory of Open Access Journals (Sweden)

    Nicole J W de Wit

    Full Text Available Human intestinal tissue samples are barely accessible to study potential health benefits of nutritional compounds. Numbers of animals used in animal trials, however, need to be minimalized. Therefore, we explored the applicability of in vitro (human Caco-2 cells and ex vivo intestine models (rat precision cut intestine slices and the pig in-situ small intestinal segment perfusion (SISP technique to study the effect of food compounds. In vitro digested yellow (YOd and white onion extracts (WOd were used as model food compounds and transcriptomics was applied to obtain more insight into which extent mode of actions depend on the model. The three intestine models shared 9,140 genes which were used to compare the responses to digested onions between the models. Unsupervised clustering analysis showed that genes up- or down-regulated by WOd in human Caco-2 cells and rat intestine slices were similarly regulated by YOd, indicating comparable modes of action for the two onion species. Highly variable responses to onion were found in the pig SISP model. By focussing only on genes with significant differential expression, in combination with a fold change > 1.5, 15 genes showed similar onion-induced expression in human Caco-2 cells and rat intestine slices and 2 overlapping genes were found between the human Caco-2 and pig SISP model. Pathway analyses revealed that mainly processes related to oxidative stress, and especially the Keap1-Nrf2 pathway, were affected by onions in all three models. Our data fit with previous in vivo studies showing that the beneficial effects of onions are mostly linked to their antioxidant properties. Taken together, our data indicate that each of the in vitro and ex vivo intestine models used in this study, taking into account their limitations, can be used to determine modes of action of nutritional compounds and can thereby reduce the number of animals used in conventional nutritional intervention studies.

  5. Natural compound methyl protodioscin protects against intestinal inflammation through modulation of intestinal immune responses

    OpenAIRE

    Zhang, Rongli; Gilbert, Shila; Yao, Xinsheng; Vallance, Jefferson; Steinbrecher, Kris; Moriggl, Richard; Zhang, Dongsheng; Eluri, Madhu; Chen, Haifeng; Cao, Huiqing; Shroyer, Noah; Denson, Lee; Han, Xiaonan

    2015-01-01

    Dioscoreaceae, a kind of yam plant, has been recommended for treatment of chronic inflammatory conditions. However, the mechanisms are poorly defined. Methyl protodioscin (MPD) is one of the main bioactive components in Dioscoreaceae. Here, we aim to determine the mechanisms by which MPD ameliorates intestinal inflammation. Surgical intestinal specimens were collected from inflammatory bowel diseases (IBD) patients to perform organ culture. Experimental colitis was induced in mice by dextran ...

  6. Transplante de intestino delgado Small intestine transplantation

    Directory of Open Access Journals (Sweden)

    Flávio Henrique Ferreira Galvão

    2003-06-01

    Full Text Available RACIONAL: Avanços da biotecnologia e o desenvolvimento de novas drogas imunossupressoras melhoraram os resultados do transplante de intestino delgado. Esse transplante é atualmente indicado para casos especiais da falência intestinal. OBJETIVO: A presente revisão realça os recentes desenvolvimentos na área do transplante de intestino delgado. MATERIAL E MÉTODO: Mais de 600 publicações de transplante de intestino delgado foram revisadas. O desenvolvimento da pesquisa, novas estratégias de imunossupressão, monitorização do enxerto e do receptor, e avanços na técnica cirúrgica são discutidos. RESULTADOS: Realizaram-se cerca de 700 transplante de intestino delgado em 55 centros: 44% intestino-fígado, 41% enxerto intestinal isolado e 15% transplante multivisceral. Rejeição e infecção são as principais limitações desse transplante. Sobrevida de 5 anos na experiência internacional é de 46% para o transplante de intestino isolado, 43% para o intestino-fígado e de cerca de 30% para o transplante multivisceral. Sobrevidas prolongadas são mais freqüentes nos centros com maior experiência. Em série de 165 transplantes intestinais na Universidade de Pittsburgh, PA, EUA, foi relatada sobrevida do paciente maior do que 75% no primeiro ano, 54% em 5 anos e 42% em 10 anos. Mais de 90% desses pacientes assumem dieta oral irrestrita. CONCLUSÃO: O transplante de intestino delgado evoluiu de estratégia experimental para uma alternativa viável no tratamento da falência intestinal permanente. Promover o refinamento da terapia imunossupressora, do manejo e prevenção de infecções, da técnica cirúrgica e da indicação e seleção adequada dos pacientes é crucial para melhorar a sobrevida desse transplante.BACKGROUND: Significant progress has been made in clinical small bowel transplantation over the last decade mainly due advances in biotechnology and new immunosuppressive regiments. This transplantation has now been indicated

  7. [The complications of intestinal stoma in children].

    Science.gov (United States)

    Minaev, S V; Bykov, N I; Isaeva, A V; Kachanov, A V; Tovkan, E A; Filip'yeva, N V; Gerasimenko, I N

    To investigate the complications of intestinal stoma in children and to develop measures for decrease of their incidence. The study included 152 children with congenital and acquired gastrointestinal pathology requiring surgical treatment with the imposition of intestinal stoma. Atresia of intestinal tube was observed in 28 (18.4%) children, meconium ileus - in 10 (6.6%) cases, Hirschsprung's disease - in 11 (7.2%)cases, anorectal malformations - in 39 (25.7%) cases, multiple malformations - in 11 (7.2%) patients, necrotic enterocolitis - in 56 (36.8%) patients, other reasons - in 7 (4.6%) cases. The average age of patients was 12,3±7,2 days. There were 93 (61.2%) boys and 59 (38.8%) girls. Ileostomy, ileocolostomy and colostomy were made in 37 (24.3%), 46 (30.3%) and 69 (45.4%) cases respectively. Time of intestinal stoma function was 18-217 days. Early complications were dehiscence in the area of stoma in 4 (2.6%) children, evagination in 7 (4.6%) patients, marginal necrosis of stoma in 2 (1.3%) cases, retraction of stomy into abdominal cavity in 1 (0.6%) child and abdominal skin maceration in 8 (5.2%) patients. Remote complications included dermatitis around stomy in 35 (23.1%) children, stenosis of stoma in 9 (5.9%) cases, evagination of stoma in 12 (7.9%) patients. Also, 5 patients were unable to use the colostomy bag due to vicious overlaying of intestinal stoma. Using the colostomy bags «Coloplast» and skin care products around the stoma significantly reduced (pstoma depends on not only technical aspects but also obligatory care performance with timely correction of complications.

  8. Role of Smooth Muscle in Intestinal Inflammation

    Directory of Open Access Journals (Sweden)

    Stephen M Collins

    1996-01-01

    Full Text Available The notion that smooth muscle function is altered in inflammation is prompted by clinical observations of altered motility in patients with inflammatory bowel disease (IBD. While altered motility may reflect inflammation-induced changes in intrinsic or extrinsic nerves to the gut, changes in gut hormone release and changes in muscle function, recent studies have provided in vitro evidence of altered muscle contractility in muscle resected from patients with ulcerative colitis or Crohn’s disease. In addition, the observation that smooth muscle cells are more numerous and prominent in the strictured bowel of IBD patients compared with controls suggests that inflammation may alter the growth of intestinal smooth muscle. Thus, inflammation is associated with changes in smooth muscle growth and contractility that, in turn, contribute to important symptoms of IBD including diarrhea (from altered motility and pain (via either altered motility or stricture formation. The involvement of smooth muscle in this context may be as an innocent bystander, where cells and products of the inflammatory process induce alterations in muscle contractility and growth. However, it is likely that intestinal muscle cells play a more active role in the inflammatory process via the elaboration of mediators and trophic factors, including cytokines, and via the production of collagen. The concept of muscle cells as active participants in the intestinal inflammatory process is a new concept that is under intense study. This report summarizes current knowledge as it relates to these two aspects of altered muscle function (growth and contractility in the inflamed intestine, and will focus on mechanisms underlying these changes, based on data obtained from animal models of intestinal inflammation.

  9. Determination of Intestine Inflammation Markers in Diagnostic Search in Children with Intestinal Diseases

    Directory of Open Access Journals (Sweden)

    N.V. Pavlenko

    2016-08-01

    Full Text Available Introduction. Prevalence of bowel diseases in children is the second, trailing only the diseases of gastroduodenal zone and growing in recent years. Actual one is the problem of differential diagnosis of functional and inflammatory intestinal diseases using non-invasive methods on the prehospital stage and as a screening. Objective. Comparative analysis of fecal markers of the bowel inflammation (lactoferrine and calprotectine with endoscopy and morphology of intestinal mucosa in children. Matherials and methods. 49 children aged 6–18 years were examined. All patients underwent endoscopic and morphological study of the intestine, coprotest, determination of fecal markers of bowel inflammation (lactoferrin and calprotectine. Results. It is shown that in young children, the intestinal mucosa mainly hadn’t endoscopic changes, coprotest and morphological examination didn’t reveal the signs of inflammation, fecal intestinal inflammation markers were negative (p < 0.05. In the group of older children, moderate or marked catarrhal changes were found endoscopically, coprotest results were typical of inflammation in the intestines, it was morphologically proved the presence of chronic inflammation of the mucous membrane of the colon with signs of atrophy, the results of lactoferrin and calprotectine determination were positive (p < 0.05. Conclusion. The findings suggest that the evaluation of calprotectine and lactoferrin can be used in pediatric patients because of its non-invasiveness as diagnostic screening for the selection of patients for the further endoscopic examination and diagnostic search.

  10. Activated STAT5 Confers Resistance to Intestinal Injury by Increasing Intestinal Stem Cell Proliferation and Regeneration

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    Shila Gilbert

    2015-02-01

    Full Text Available Intestinal epithelial stem cells (IESCs control the intestinal homeostatic response to inflammation and regeneration. The underlying mechanisms are unclear. Cytokine-STAT5 signaling regulates intestinal epithelial homeostasis and responses to injury. We link STAT5 signaling to IESC replenishment upon injury by depletion or activation of Stat5 transcription factor. We found that depletion of Stat5 led to deregulation of IESC marker expression and decreased LGR5+ IESC proliferation. STAT5-deficient mice exhibited worse intestinal histology and impaired crypt regeneration after γ-irradiation. We generated a transgenic mouse model with inducible expression of constitutively active Stat5. In contrast to Stat5 depletion, activation of STAT5 increased IESC proliferation, accelerated crypt regeneration, and conferred resistance to intestinal injury. Furthermore, ectopic activation of STAT5 in mouse or human stem cells promoted LGR5+ IESC self-renewal. Accordingly, STAT5 promotes IESC proliferation and regeneration to mitigate intestinal inflammation. STAT5 is a functional therapeutic target to improve the IESC regenerative response to gut injury.

  11. [Morphological changes of the intestine in experimental acute intestinal infection in the treatment of colloidal silver].

    Science.gov (United States)

    Polov'ian, E S; Chemich, N D; Moskalenko, R A; Romaniuk, A N

    2012-06-01

    At the present stage of infectionist practice in the treatment of acute intestinal infections caused by opportunistic microorganisms, colloidal silver is used with a particle size of 25 nm as an alternative to conventional causal therapy. In 32 rats, distributed in 4 groups of 8 animals each (intact; healthy, got colloidal silver; with a modeled acute intestinal infection in the basic treatment and with the addition of colloidal silver), histological examination was performed of small and large intestine of rats. Oral administration of colloidal silver at a dose of 0.02 mg/day to intact rats did not lead to changes in morphometric parameters compared to the norm, and during early convalescence in rats with acute intestinal infections were observed destructive and compensatory changes in the intestine, which depended on the treatment regimen. With the introduction of colloidal silver decreased activity of the inflammatory process and the severity of morphological changes in tissues of small and large intestine, indicating that the positive effect of study drug compared with baseline therapy.

  12. Precision cut intestinal slices are an appropriate ex vivo model to study NSAID-induced intestinal toxicity in rats

    NARCIS (Netherlands)

    Niu, Xiaoyu; de Graaf, Inge A. M.; van der Bij, Hendrik A.; Groothuis, Geny M. M.

    2014-01-01

    Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used therapeutic agents, however, they are associated with a high prevalence of intestinal side effects. In this investigation, rat precision cut intestinal slices (PCIS) were evaluated as an ex vivo model to study NSAID-induced intestinal

  13. Algunas mutaciones del derecho originario en el proceso de integración europea = Some mutations in the primary law during the european integration process

    OpenAIRE

    Allué Buiza, Alfredo

    2012-01-01

    La Integración Europea es de carácter jurídico internacional y también constitucional. Existen procesos de reforma intergubernamental, procesos cuasiconstituyentes, y procesos de mutación constitucional. Estos últimos procesos han existido a lo largo de todo el proceso de integración. Las mutaciones han inspirado posteriormente los cambios en el derecho originario.European integration has a legal character, international but also constitutional. There are intergovernmental refo...

  14. Alternative Functional In Vitro Models of Human Intestinal Epithelia

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    Amanda L Kauffman

    2013-07-01

    Full Text Available Physiologically relevant sources of absorptive intestinal epithelial cells are crucial for human drug transport studies. Human adenocarcinoma-derived intestinal cell lines, such as Caco-2, offer conveniences of easy culture maintenance and scalability, but do not fully recapitulate in vivo intestinal phenotypes. Additional sources of renewable physiologically relevant human intestinal cells would provide a much needed tool for drug discovery and intestinal physiology. We sought to evaluate and compare two alternative sources of human intestinal cells, commercially available primary human intestinal epithelial cells (hInEpCs and induced pluripotent stem cell (iPSC-derived intestinal cells to Caco-2, for use in in vitro transwell monolayer intestinal transport assays. To achieve this for iPSC-derived cells, our previously described 3-dimensional intestinal organogenesis method was adapted to transwell differentiation. Intestinal cells were assessed by marker expression through immunocytochemical and mRNA expression analyses, monolayer integrity through Transepithelial Electrical Resistance (TEER measurements and molecule permeability, and functionality by taking advantage the well-characterized intestinal transport mechanisms. In most cases, marker expression for primary hInEpCs and iPSC-derived cells appeared to be as good as or better than Caco-2. Furthermore, transwell monolayers exhibited high TEER with low permeability. Primary hInEpCs showed molecule efflux indicative of P-glycoprotein transport. Primary hInEpCs and iPSC-derived cells also showed neonatal Fc receptor-dependent binding of immunoglobulin G variants. Primary hInEpCs and iPSC-derived intestinal cells exhibit expected marker expression and demonstrate basic functional monolayer formation, similar to or better than Caco-2. These cells could offer an alternative source of human intestinal cells for understanding normal intestinal epithelial physiology and drug transport.

  15. El debido proceso como derecho fundamental de los estudiantes universitarios en los procesos sancionatorios adelantados por las universidades: un análisis a partir de la jurisprudencia de la corte constitucional colombiana

    OpenAIRE

    Ana Patricia Pabón Mantilla; Silvia Juliana Pradilla Rivera; Cesar Javier Valencia Caballero

    2008-01-01

    Se presenta un análisis realizado con base en los pronunciamientos emanados de la Corte Constitucional en lo que se refiere a los procesos disciplinarios adelantados por las universidades a estudiantes. Se contemplan aspectos como la autonomía universitaria, el debido proceso, el derecho a la educación. Se busca identificar los elementos mínimos que deben contener los procesos disciplinarios para que se ajusten al respeto del derecho al debido proceso y al derecho a...

  16. El debido proceso como derecho fundamental de los estudiantes universitarios en los procesos sancionatorios adelantados por las universidades: un análisis a partir de la jurisprudencia de la corte constitucional colombiana

    Directory of Open Access Journals (Sweden)

    Ana Patricia Pabón Mantilla

    2008-01-01

    Full Text Available Se presenta un análisis realizado con base en los pronunciamientos emanados de la Corte Constitucional en lo que se refiere a los procesos disciplinarios adelantados por las universidades a estudiantes. Se contemplan aspectos como la autonomía universitaria, el debido proceso, el derecho a la educación. Se busca identificar los elementos mínimos que deben contener los procesos disciplinarios para que se ajusten al respeto del derecho al debido proceso y al derecho a la igualdad.

  17. LA GESTIÓN POR PROCESOS: UN ENFOQUE DE GESTIÓN EFICIENTE

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    Miguel Ángel Mallar

    2010-01-01

    Full Text Available Cada vez más se observan los esfuerzos orientados a adecuar las organizaciones al complejo escenario en que se mueven. Cambios de reglas de juego, incremento de la competencia, apertura al mundo a través de la tecnología, hacen al cliente mucho más exigente, modificando sus demandas y necesidades.La Gestión basada en los Procesos, surge como un enfoque que centra la atención sobre las actividades de la organización, para optimizarlas.En este trabajo se considerará a la organización como una red de procesos interrelacionados o interconectados, donde la estructura organizativa vertical clásica, eficiente a nivel de funciones, se orienta hacia una concepción horizontal, desplazándose el centro de interés desde las estructuras hacia los procesos, como metodología para mejorar el rendimiento, concentrándose en el diseño disciplinado y cuidadosa ejecución de todos los procesos de una organización.Concluyendo, la metodología de aplicación de la Gestión basada en Procesos se trata de una herramienta de gestión adecuada para el momento actual, constituyéndose con fuerza como una alternativa exitosa para la obtención de resultados cada vez mejores.

  18. Beneficios de la aplicación de normas internacionales ISO en procesos electorales

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    Jeffrey Badí Quinteros Basantes

    2017-01-01

    Full Text Available En este artículo se presentarán los beneficios de la aplicabilidad de las normas internacionales ISO en los procesos electorales, con el fin de poder elevar los niveles de percepción positiva de los ciudadanos. Se verificará la aplicación de normas ISO/TS 17582:2014, Sistemas de Gestión de la Calidad y la norma ISO/IEC 27001:2013, para todas las fases de un proceso electoral. Se expondrán los dominios que forman parte de la norma ISO/TS 17582:2014 , los cuales permiten un proceso de mejoramiento continuo a fin de garantizar la calidad de las metodologías que soportan la organización, administración, gestión, seguimiento y auditorías de un proceso electoral. La norma ISO/IEC 27001:2013 se alinea con la norma ISO9001:2008 para la gestión de seguridad de la información. La aplicación de esta normativa permitirá asegurar la integridad, confidencialidad y disponibilidad de la información durante los procesos electorales.

  19. Importancia de las diferencias entre actividad-procedimiento-proceso para la autoevaluación institucional universitaria

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    Hernando A. Romero

    2002-01-01

    Full Text Available Se refiere en una amplia reflexión, a que tener clara la diferencia de significados entre actividad, procedimiento-proceso, actividad social, proceso social y personal es muy importante en el campo de la autoevaluación institucional porque si no se reconocen sus diferencias, no se puede aludir correctamente lo que se entiende por actividad académica y las diferencias en el proceso pedagógico

  20. Autophagy and tight junction proteins in the intestine and intestinal diseases

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    Chien-An A. Hu

    2015-09-01

    Full Text Available The intestinal epithelium (IE forms an indispensible barrier and interface between the intestinal interstitium and the luminal environment. The IE regulates water, ion and nutrient transport while providing a barrier against toxins, pathogens (bacteria, fungi and virus and antigens. The apical intercellular tight junctions (TJ are responsible for the paracellular barrier function and regulate trans-epithelial flux of ions and solutes between adjacent cells. Increased intestinal permeability caused by defects in the IE TJ barrier is considered an important pathogenic factor for the development of intestinal inflammation, diarrhea and malnutrition in humans and animals. In fact, defects in the IE TJ barrier allow increased antigenic penetration, resulting in an amplified inflammatory response in inflammatory bowel disease (IBD, necrotizing enterocolitis and ischemia-reperfusion injury. Conversely, the beneficial enhancement of the intestinal TJ barrier has been shown to resolve intestinal inflammation and apoptosis in both animal models of IBD and human IBD. Autophagy (self-eating mechanism is an intracellular lysosome-dependent degradation and recycling pathway essential for cell survival and homeostasis. Dysregulated autophagy has been shown to be directly associated with many pathological processes, including IBD. Importantly, the crosstalk between IE TJ and autophagy has been revealed recently. We showed that autophagy enhanced IE TJ barrier function by increasing transepithelial resistance and reducing the paracellular permeability of small solutes and ions, which is, in part, by targeting claudin-2, a cation-selective, pore-forming, transmembrane TJ protein, for lysosome (autophagy-mediated degradation. Interestingly, previous studies have shown that the inflamed intestinal mucosa in patients with active IBD has increased claudin-2 expression. In addition, inflammatory cytokines (for example, tumor necrosis factor-α, interleukin-6

  1. Regulation of intestinal homeostasis by innate immune cells.

    Science.gov (United States)

    Kayama, Hisako; Nishimura, Junichi; Takeda, Kiyoshi

    2013-12-01

    The intestinal immune system has an ability to distinguish between the microbiota and pathogenic bacteria, and then activate pro-inflammatory pathways against pathogens for host defense while remaining unresponsive to the microbiota and dietary antigens. In the intestine, abnormal activation of innate immunity causes development of several inflammatory disorders such as inflammatory bowel diseases (IBD). Thus, activity of innate immunity is finely regulated in the intestine. To date, multiple innate immune cells have been shown to maintain gut homeostasis by preventing inadequate adaptive immune responses in the murine intestine. Additionally, several innate immune subsets, which promote Th1 and Th17 responses and are implicated in the pathogenesis of IBD, have recently been identified in the human intestinal mucosa. The demonstration of both murine and human intestinal innate immune subsets contributing to regulation of adaptive immunity emphasizes the conserved innate immune functions across species and might promote development of the intestinal innate immunity-based clinical therapy.

  2. Surgical management of radiation injury to the small intestine

    Energy Technology Data Exchange (ETDEWEB)

    Swan, R.W.; Fowler, W.C. Jr., Boronow, R.C.

    1976-01-01

    Severe injury of the small intestine represents one of the most tragic complications of radiation of the pelvis and abdomen. Not uncommonly, patients die from the radiation or the treatment of its intestinal complications. More commonly, patients become intestinal cripples, secondary to chronic partial obstruction of the small intestine and malnutrition associated with the stagnant loop syndrome, as previously reported by one of us. Management results have been discouraging, usually because of a general lack of clinical recognition and understanding of radiation injury to the intestine. Medical management has not been satisfactory. It may provide temporary relief from symptoms, but not long-lasting. Surgical management, although frequently curative, has been associated with high death and morbidity rates. Many surgical procedures have been used in treating radiation injury to the small intestine. Generally, these fall into two categories: first, intestinal resection with primary anastomosis; and second, enteroenteric or enterocolic bypass. In the literature are reflected advocates for each method of surgical management.

  3. Intestinal mucus accumulation in a child with acutemyeloblastic leukemia

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    Namık Özbek

    2009-12-01

    Full Text Available Intestinal mucus accumulation is a very rare situation observed in some solid tumors, intestinal inflammation, mucosal hyperplasia, elevated intestinal pressure, and various other diseases. However, it has never been described in acute myeloblastic leukemia. The pathogenesis of intestinal mucus accumulation is still not clear. Here, we report a 14-year-old girl with acute myeloblastic leukemia and febrile neutropenia in addition to typhlitis. She was also immobilized due to joint contractures of the lower extremities and had intestinal mucus accumulation, which was, at first, misdiagnosed as intestinal parasitosis. We speculate that typhlitis, immobilization and decreased intestinal motility due to usage of antiemetic drugs might have been the potential etiologic factors in this case. However, its impact on prognosis of the primary disease is unknown.

  4. Seguimiento de un proceso de fermentación en una bodega del Penedés

    OpenAIRE

    Carrillo Pujante, Míriam

    2007-01-01

    El proyecto trata del proceso de elaboración del vino, concretamente del proceso de fermentación alcohólica. Dicho proceso tiene una gran importancia ya que durante éste es cuando se produce la transformación del azúcar en alcohol mediante levaduras. Durante la fermentación alcohólica hay que realizar una serie de controles, análisis, para ver si dicho proceso sigue en marcha o se ha parado. Y además, los análisis son para comprobar que los parámetros como la acidez, ...

  5. [Intestinal transplant: in what phase are we?].

    Science.gov (United States)

    Andrés Moreno, A M; Ramos, E; Hernández, F; Encinas, J L; Leal, N; Gámez, M L; Martínez, L; Sarriá, J; Molina, M; Martínez-Ojinaga, E; Murcia, J; Frauca, E; Delgado, M; Prieto, G; López Santamaría, M; Tovar, J A

    2010-07-01

    To analyze the evolution of Small Bowel Transplantation program since the beginning of the program. [corrected] All children who underwent intestinal transplantation between 1997 and 2009 were retrospectively reviewed: epidemiological data, status before transplant, surgical technique, immunosupression, results, survival and long.term quality of life were analysed. Fifty-two intestinal transplants were performed in 46 children (20 isolated bowel, 20 combined liver and intestine, and 12 multivisceral); median age was 32m (range 7m-19a); weight 12,3 kg (range 3,9-60); 31 had short gut syndrome, 8 dismotility, 5 intractable diarrhea, and two were miscellaneous. Intestinal adaptation was initially attempted in 26 patients, without success, 20 were directly listed for transplant. The modality of transplant was modified in 17 while listed. Baseline immunosupression consisted of tacrolimus and steroids, although 5 required conversion to Sirolimus later. Six died during the first month, due to sepsis/multiorganic failure (poor status at transplant); 13 died during the long-term follow-up. Acute rejection was seen in 20, chronic rejection in 3, PTLD in 8 (6 died) and GVHD in 5 patients (3 died). Overall survival after 5 years of follow-up is 65,2 % (51,7% for the graft). From 2006 to 2008, overall patient/graft survival at 6 m, 1 and 3 years after transplant is 88,7/84,1, 81,2/81,2 and 81,2/71,1%, respectively. After a median follw-up of 39 +/- 29 months, 27 patients are alive (59%), off TPN, (70% had their ostomy taken down), go to school, are scarcely hospitalized and enjoy a good quality of life. Intestinal transplantation has consolided itself as a good choice for irreversible intestinal failure, being feasible to achieve a normal life. Although overall survival diminishes over time, the center experience has improved the results. These patients need a very close follow-up, once transplant is over, in order to get an early diagnose of immunological complications.

  6. Mechanisms of Intestinal Barrier Dysfunction in Sepsis.

    Science.gov (United States)

    Yoseph, Benyam P; Klingensmith, Nathan J; Liang, Zhe; Breed, Elise R; Burd, Eileen M; Mittal, Rohit; Dominguez, Jessica A; Petrie, Benjamin; Ford, Mandy L; Coopersmith, Craig M

    2016-07-01

    Intestinal barrier dysfunction is thought to contribute to the development of multiple organ dysfunction syndrome in sepsis. Although there are similarities in clinical course following sepsis, there are significant differences in the host response depending on the initiating organism and time course of the disease, and pathways of gut injury vary widely in different preclinical models of sepsis. The purpose of this study was to determine whether the timecourse and mechanisms of intestinal barrier dysfunction are similar in disparate mouse models of sepsis with similar mortalities. FVB/N mice were randomized to receive cecal ligation and puncture (CLP) or sham laparotomy, and permeability was measured to fluoresceinisothiocyanate conjugated-dextran (FD-4) six to 48 h later. Intestinal permeability was elevated following CLP at all timepoints measured, peaking at 6 to 12 h. Tight junction proteins claudin 1, 2, 3, 4, 5, 7, 8, 13, and 15, Junctional Adhesion Molecule-A (JAM-A), occludin, and ZO-1 were than assayed by Western blot, real-time polymerase chain reaction, and immunohistochemistry 12 h after CLP to determine potential mechanisms underlying increases in intestinal permeability. Claudin 2 and JAM-A were increased by sepsis, whereas claudin-5 and occludin were decreased by sepsis. All other tight junction proteins were unchanged. A further timecourse experiment demonstrated that alterations in claudin-2 and occludin were detectable as early as 1 h after the onset of sepsis. Similar experiments were then performed in a different group of mice subjected to Pseudomonas aeruginosa pneumonia. Mice with pneumonia had an increase in intestinal permeability similar in timecourse and magnitude to that seen in CLP. Similar changes in tight junction proteins were seen in both models of sepsis although mice subjected to pneumonia also had a marked decrease in ZO-1 not seen in CLP. These results indicate that two disparate, clinically relevant models of sepsis

  7. La protección del menor en el proceso judicial de prodigalidad. La protección del menor en el proceso judicial de prodigalidad *.

    Directory of Open Access Journals (Sweden)

    Sonia Calaza López

    2011-09-01

    Full Text Available En este ensayo se analiza la posible reinvención del proceso de prodigalidad desde la perspectiva de la protección de los menores. En este sentido, proponemos la regulación de un proceso de prodigalidad ágil, dinámico, eficaz, sencillo y económico, que, sin merma de garantías procesales, otorgue, en breve espacio de tiempo, adecuada satisfacción a las necesidades de los alimentistas frente a sus alimentantes.In this test there is analyzed the possible reinvention of the process of prodigality from the perspective of the protection of the minors. In this respect, we propose the regulation of a process, dynamic, effective, simple and economic of agile prodigality, that, without wastage of procedural guarantees, it grants, shortly lapse of time, suitable satisfaction to the needs of the alimentistas opposite to his alimentantes.

  8. La educación emocional, su importancia en el proceso de aprendizaje

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    José Ángel García Retana

    2012-01-01

    Full Text Available Dentro del proceso educativo, se ha tendido a privilegiar los aspectos cognitivos por encima de los emocionales. Incluso para muchos estos dos aspectos deben ser considerados por separado; sin embargo esto no es conveniente si se pretende lograr el desarrollo integral del educando. Para poder incorporar los aspectos emocionales en el proceso educativo se debe caracterizar en qué consisten las emociones, cómo a partir de estas surge la educación emocional y qué papel juega esta dentro de dicho proceso. A su vez, se debe considerar el papel del maestro y cómo las emociones -tanto propias como de los estudiantes-, deben ser tomadas en cuenta en su acto pedagógico; por último se considerará la relación entre emociones y estilos de aprendizaje.

  9. Calidad superficial en el prototipado rápido, proceso fdm

    OpenAIRE

    Vargas Henríquez, Lisandro; Córdoba Nieto, Ernesto

    2010-01-01

    Este artículo es una síntesis de la tesis de maestría en el Posgrado de Materiales y Procesos de Manufactura, del Departamento de Ingeniería Mecánica y Mecatrónica. El paper muestra la interacción de los parámetros del proceso, distancia de la deposición (Gap) y la velocidad del cabezal de extrusión, para la máquina Titán SH-1 de prototipado rápido, proceso de modelado por deposición fundida de material (FDM), del CEIF (Centro de tensión de los prototipos y la caracterización del material. El...

  10. LAS COMPETENCIAS INVESTIGATIVAS DEL ESTUDIANTE EN EL PROCESO DE ENSEÑANZA APRENDIZAJE

    OpenAIRE

    Pablo Enrique Barreiro Macías

    2015-01-01

    El presente estudio ofrece una concepción teórica referente a la formación de las competencias investigativas del estudiante de laboratorio clínico. Como metodología general, se realizó un análisis crítico y argumentado en el contexto de la profesión, referente a la importancia de la investigación científica, en el proceso de enseñanza y aprendizaje, conceptualizada ésta, como el “proceso esencial” para la formación de las competencias investigativas. Se propone que el proceso de enseñanza y ...

  11. Los procesos iniciales de lecto-escritura en el nivel de educación inicia

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    Ana Lupita Chaves Salas

    2002-01-01

    Full Text Available El análisis de los procesos iniciales de lecto-escritura, propósito de este artículo, parte de una descripción de la función de la educación inicial y de cómo en este nivel se han incentivado dichos procesos. Posteriormente, se estudia la apropiación de la lengua escrita por parte de la niña y el niño, concebida como un proceso constructivo, interactivo y de producción cultural. Finalmente, se hacen algunas reflexiones con el fin de provocar la discusión en torno a este tema entre las personas interesadas, y así, contribuir a la transformación del nivel inicial del sistema educativo costarricense.

  12. MEMORIAS DEL TRABAJO ANTE LOS PROCESOS DE PRIVATIZACIÓN EN ARGENTINA

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    Hernán Palermo

    2011-01-01

    Full Text Available El objetivo del artículo es analizar de qué modo los procesos de privatización en Argentina implicaron la desestructuración de un orden sociolaboral y simbólico, que organizaba la vida de dos colectivos de trabajadores vinculados con la extracción de petróleo y la producción de acero. Realiza una reflexión sobre los sentidos y valores que se diputan en los procesos de construcción de la memoria, rastreando continuidades y rupturas. Como común denominador encuentra que el proceso privatizador, así como la conversión de los trabajadores en emprendedores, representa un punto de ruptura que dificulta y complejiza la transmisión de la experiencia.

  13. Memorias del trabajo ante los procesos de privatización en argentina

    Directory of Open Access Journals (Sweden)

    Hernán Palermo

    2011-04-01

    Full Text Available El objetivo del artículo es analizar de qué modo los procesos de privatización en Argentina implicaron la desestructuración de un orden sociolaboral y simbólico, que organizaba la vida de dos colectivos de trabajadores vinculados con la extracción de petróleo y la producción de acero. Realiza una reflexión sobre los sentidos y valores que se diputan en los procesos de construcción de la memoria, rastreando continuidades y rupturas. Como común denominador encuentra que el proceso privatizador, así como la conversión de los trabajadores en emprendedores, representa un punto de ruptura que dificulta y complejiza la transmisión de la experiencia.

  14. Procesos iniciales de lecto-escritura en el nivel de educación inicial

    Directory of Open Access Journals (Sweden)

    Chaves Salas, Ana Lupita

    2002-06-01

    Full Text Available El análisis de los procesos iniciales de lecto-escritura, propósito de este artículo, parte de una descripción de la función de la educación inicial y de cómo en este nivel se han incentivado dichos procesos. Posteriormente, se estudia la apropiación de la lengua escrita por parte de la niña y el niño, concebida como un proceso constructivo, interactivo y de producción cultural. Finalmente, se hacen algunas reflexiones con el fin de provocar la discusión en torno a este tema entre las personas interesadas, y así, contribuir a la transformación del nivel inicial del sistema educativo costarricense.

  15. Estudio de ventajas energéticas en un proceso de destilación

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    Carlos Ariel Cardona Alzate

    2013-04-01

    Full Text Available Este trabajo desarrolla un método para comparar los gastos energéticos entre las configuraciones secuencial (reacción-separación y simultánea (destilación reactiva, analizando los flujos internos y externos de un proceso. Como ejemplo se utilizó una reacción tipo: A + B D C + D; con temperaturas de saturación: TCσprocesos convencionales para este tipo de procesos.

  16. Intestinal Stem Cell Markers in the Intestinal Metaplasia of Stomach and Barrett's Esophagus.

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    Bo Gun Jang

    Full Text Available Gastric intestinal metaplasia (IM is a highly prevalent preneoplastic lesion; however, the molecular mechanisms regulating its development remain unclear. We have previously shown that a population of cells expressing the intestinal stem cell (ISC marker LGR5 increases remarkably in IM. In this study, we further investigated the molecular characteristics of these LGR5+ cells in IM by examining the expression profile of several ISC markers. Notably, we found that ISC markers-including OLFM4 and EPHB2-are positively associated with the CDX2 expression in non-tumorous gastric tissues. This finding was confirmed in stomach lesions with or without metaplasia, which demonstrated that OLFM4 and EPHB2 expression gradually increased with metaplastic progression. Moreover, RNA in situ hybridization revealed that LGR5+ cells coexpress several ISC markers and remained confined to the base of metaplastic glands, reminiscent to that of normal intestinal crypts, whereas those in normal antral glands expressed none of these markers. Furthermore, a large number of ISC marker-expressing cells were diffusely distributed in gastric adenomas, suggesting that these markers may facilitate gastric tumorigenesis. In addition, Barrett's esophagus (BE-which is histologically similar to intestinal metaplasia-exhibited a similar distribution of ISC markers, indicating the presence of a stem cell population with intestinal differentiation potential. In conclusion, we identified that LGR5+ cells in gastric IM and BE coexpress ISC markers, and exhibit the same expression profile as those found in normal intestinal crypts. Taken together, these results implicate an intestinal-like stem cell population in the pathogenesis of IM, and provide an important basis for understanding the development and maintenance of this disease.

  17. Propuesta de un proceso de enseñanza-aprendizaje para la asignatura Diseño de Software como proceso de software

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    Lund, María Inés

    2014-04-01

    Full Text Available La cátedra Diseño de Software se dicta actualmente en 4º año de las carreras del Departamento de Informática de la Facultad de Ciencias Exactas, Físicas y Naturales (FCEFN de la Universidad Nacional de San Juan (UNSJ. Esta materia se enfoca principalmente al Diseño Orientado a Objetos (DOO, brindando conceptos y conocimientos desarrollados en forma teórica y con un fuerte componente práctico, de todos los diagramas de modelado de software que provee el Lenguaje de Modelado Unificado (UML, con el fin de comprender acabadamente el objetivo que se persigue con cada uno de ellos y en qué casos es conveniente o útil aplicarlos. El presente trabajo se sustenta de la experiencia adquirida en la práctica aplicada para la enseñanza de DOO, utilizando UML para el modelado, donde las actividades prácticas abarcan desde el análisis hasta llegar a una propuesta de diseño de implementación. Se presenta un modelo de proceso de enseñanza aprendizaje, como proceso de software, y los artefactos utilizados para guiar al alumno en la resolución de un problema de desarrollo de software específico, utilizando para su especificación el lenguaje de metamodelado de procesos SPEM 2.0 y para generar el modelado del proceso de software la herramienta Eclipse Process Framework Composer (EPFC.

  18. Herramienta para establecer y controlar Iniciativas de Mejora de Procesos con MoProSoft

    Directory of Open Access Journals (Sweden)

    Dagoberto Cruz Sandoval

    2015-02-01

    Full Text Available La mejora de procesos software es una disciplina cuya premisa es que un proceso de calidad tiene como consecuencia lógica un producto software de calidad. En México, una industria software emergente y compuesta en su mayoría por micro y pequeñas empresas, ha empezado a incursionar en este tipo de disciplina utilizando el modelo mexicano de mejora de procesos conocido como MoProSoft, sin embargo la carencia de conocimiento y experiencia, hace de este tipo de proyectos algo complicado y desgastante. En el presente trabajo se presenta el desarrollo de un marco de trabajo para las micro y pequeñas empresas desarrolladoras de software en México, el cual es apoyado por una herramienta llamada Kaizen que automatiza las fases básicas de una mejora de procesos: compromiso, evaluación, planeación e implementación basadas en los procesos, actividades, prácticas y roles definidos en MoProSoft. La herramienta tiene como objetivo principal proporcionar apoyo a las micro empresas en las iniciativas de mejora por medio de un marco de actividades automatizadas que guían sus pasos durante la ejecución del programa de mejora. Además, se presenta un caso de estudio y resultados cuantitativos de que con el uso de Kaizen cuatro micro empresas mexicanas vieron mejorados sus procesos de desarrollo de software instaurando las prácticas efectivas definidas por MoProSoft.

  19. UN MÉTODO PARA LA TRAZABILIDAD DE REQUISITOS EN EL PROCESO UNIFICADO DE DESARROLLO

    Directory of Open Access Journals (Sweden)

    Marta Silvia Tabares

    2007-12-01

    Full Text Available El Proceso Unificado es un proceso de desarrollo adoptado por gran parte de las empresas desarrolladoras de software. Esto lleva a que atributos de calidad como la trazabilidad de requisitos deban estandarizarse para este proceso, con el fin de lograr los niveles de calidad exigidos por los clientes. Por lo general, los modelos de trazabilidad se proponen independientemente del proceso o métodos de desarrollo, y su definición y mantenimiento dependen de los criterios de calidad usados por los desarrolladores. En este artículo se presenta un método para la práctica de la trazabilidad en el Proceso Unificado de Desarrollo. El enfoque propone un flujo de trabajo para el control y soporte a la trazabilidad en las iteraciones del proceso. Dicho flujo establece un conjunto de acciones para generar modelos de trazabilidad que faciliten negociaciones oportunas con los participantes del proyecto.Unified Process is the development process adopted by many software development companies. Quality attributes, such as requirement traceability, must be standardized for this process, so that the system can achieve the quality demanded by customers. Commonly, traceability models are proposed independently of either the development process or the methodology that are followed, and its definition and maintenance depends on the quality criteria used by the developers. A traceability method for the Unified Development Process is presented in this paper. This approach proposes a workflow to control and support traceability throughout the iterations of the process. This workflow establishes a set of actions capable of generating traceability models that facilitate opportune agreement with the customers.

  20. El proceso creativo en el diseño arquitectónico

    OpenAIRE

    González Cubillán, Lesbia

    2008-01-01

    Este artículo recoge información sobre el proceso creativo seguido por estudiantes de la carrera de Arquitectura y arquitectos en ejercicio, con la finalidad de establecer las posibles diferencias entre ambos grupos. A través de un cuestionario basado en el pensamiento de Csikszentmihalyi se recogieron datos que, después de analizarlos a la luz de la complejidad humana y la energía existencial, permitió la elaboración de un conjunto de características que definen este proceso tanto e...

  1. Diseño de los procesos para industrializar la soya

    OpenAIRE

    Barrigas Romero, Cesar Orlando; Miranda, Luis

    2009-01-01

    El objetivo general es el diseño de los procesos y de las líneas de producción a escala semi industrial para la obtención de productos alimenticios a base de soya. Para ello, en la primera parte se describe a la soya como materia prima, en la fase experimental establecimos parámetros de proceso para estandarizar resultados con 1 kilo de soya como base a fin de obtener leche, queso y yogurt de soya con la parte líquida; y con la parte sólida un producto tipo granola y tortitas a base de la mez...

  2. Análisis del personal sanitario adecuado para realizar el proceso de triaje hospitalario

    OpenAIRE

    Ozámiz Monasterio, Nerea

    2014-01-01

    El proceso de triaje se puede definir como un proceso de valoración clínica preliminar, mediante el cual se ordenan a los pacientes antes de su correspondiente valoración diagnóstica y terapéutica. Existen diversos métodos de triaje en función del personal sanitario que lo realiza, pudiendo ser realizado por el personal de enfermería, por facultativos, por la combinación de ambos e incluso por cualquier persona del ámbito sanitario con una formación específica adecuada. El objetivo de...

  3. SIMULACION COMPUTACIONAL DE PROCESOS DE CONGELACION Y DESHIDRATACION PARA ALIMENTOS SOLIDOS POROSOS Y LIQUIDOS NO NEWTONIANOS

    OpenAIRE

    LEMUS MONDACA, ROBERTO ALEJANDRO

    2012-01-01

    Esta Tesis Doctoral corresponde a parte de las actividades de los Proyectos FONDECYT 1070186 y 1111067, donde se utiliza la modelación matemática y la simulación computacional para describir los fenómenos de transporte de fluidos, calor y masa que ocurren en los procesos de congelación y deshidratación de alimentos sólidos porosos y líquidos no Newtonianos. En paralelo se estudian diferentes características de gran complejidad para cada proceso térmico, como son: uso de modelos conjugados ...

  4. EL PROCEDIMIENTO MONITORIO EN EL NUEVO CODIGO ORGANICO GENERAL DE PROCESO

    OpenAIRE

    Parra Solórzano, Tania de Lourdes

    2016-01-01

    Un avance en el Código Orgánico General de Procesos, es el procedimiento monitorio, este tipo de procesos, permitirá que ciertas causas se tramiten de manera ágil; y, que aquellas deudas de hasta cincuenta salarios básicos unificados que no consten en un título ejecutivo tengan su propia vía procesal. Así cualquier documento que aparezca firmado por un deudor, desde un comprobante de entrega, una cuota de condominio, un canon de arrendamiento, o hasta una remuneración laboral n...

  5. La eficacia de la Prueba Indiciaria en el Proceso Penal Ecuatoriano

    OpenAIRE

    Pérez Medina, Lenin

    2007-01-01

    La eficacia de la prueba Indiciaria en el Proceso Penal Ecuatoriano, a tomado una nueva dimensión en nuestro sistema procesal, ya que a partir de la vigencia del nuevo Código de Procedimiento Penal, se ha orientado a garantizar la aplicación del debido proceso, en todos los parámetros que la constitución establece, en el presente trabajo estudiamos diferentes tópicos como presunción , sospecha , conjetura, vestigio, huella y rastro donde podría aparecer la prueba indiciaria, si...

  6. EL ENFOQUE DE SISTEMAS Y DE CONTINGENCIAS APLICADO AL PROCESO ADMINISTRATIVO

    OpenAIRE

    VELÁSQUEZ, FRANCISCO

    2000-01-01

    El presente artículo corresponde a una reflexión sobre el proceso administrativo de las organizaciones (las funciones de planeación, organización, dirección o influencia y control) desde la perspectiva del enfoque de sistemas y de contingencias. Para ello se abordan los planteamientos más representativos de los distintos enfoques, desde el enfoque clásico, hasta los aportes más contemporáneos. El artículo finaliza con una descripción del proceso administrat...

  7. Levantamiento de Procesos del Hospital León Becerra de Guayaquil

    OpenAIRE

    Maya Valdano, Leonardo Antonio; Medina Chávez, Marianela Sofía; Tigreros Arreaga, Dayse Mariana; Dávila Pérez, Johanna Alejandra

    2012-01-01

    En la presente investigación se desarrolló un modelo de gestión basado en procesos que le permite al Hospital León Becerra aumentar la competitividad e incrementar la calidad de los servicios de salud puesto que el entorno nacional del sector de la salud demanda cambios en la gestión de las entidades hospitalarias, de tal manera que sus estructuras, procesos y procedimientos se acoplen a las exigencias de entidades de control a nivel nacional por el Ministerio de Salud Pública e internacional...

  8. Aportes para una vida saludable. Proceso socioeducativo con estudiantes de primer ingreso, Universidad Nacional

    OpenAIRE

    Gonzalez-Soto, L.; Orozco-Morales, A.R.

    2017-01-01

    Propósito: Exponer la experiencia de medir en algún grado el impacto social de un proceso socioeducativo anual, desarrollado con 800 estudiantes de primer ingreso provenientes de diversos lugares del país, con limitadas condiciones socioeconómica y quienes son beneficiarios de beca para sus estudios. El proceso consistió en establecer 4 o 5 eventos anuales y trabajar con metodologías lúdicas temas alusivos a estilos de vida saludables. Material y método: Se aplicó la técnica de grupo focal al...

  9. Los Sistemas Gestores de Flujos de Trabajo en la Gestión de Procesos Software

    OpenAIRE

    Víctor Hugo Menéndez Domínguez; María Enriqueta Castellanos Bolaños

    2016-01-01

    Hoy en día, las empresas de software se ven obligadas a mejorar su rendimiento para poder sobrevivir en un entorno altamente competitivo: los clientes demandan una mayor calidad, menor plazo de entrega, mejor servicio, atención personalizada, etc. En este trabajo se describen a los procesos software así como los flujos de trabajo. Su combinación y automatización mejora el flujo de información asociado a las actividades de dichos procesos, lo que facilita el control y permite mejorar el rendim...

  10. Los Sistemas Gestores de Flujos de Trabajo en la Gestión de Procesos Software

    Directory of Open Access Journals (Sweden)

    Víctor Hugo Menéndez Domínguez

    2016-11-01

    Full Text Available Hoy en día, las empresas de software se ven obligadas a mejorar su rendimiento para poder sobrevivir en un entorno altamente competitivo: los clientes demandan una mayor calidad, menor plazo de entrega, mejor servicio, atención personalizada, etc. En este trabajo se describen a los procesos software así como los flujos de trabajo. Su combinación y automatización mejora el flujo de información asociado a las actividades de dichos procesos, lo que facilita el control y permite mejorar el rendimiento, reducir costos y plazos, minimizar errores y garantiza una mayor calidad, entre otras ventajas.

  11. Procesos atencionales implicados en el Trastorno por Déficit Atencional con Hiperactividad (TDAH)

    OpenAIRE

    Belmar Mellado, Marta; Navas Martínez, Leandro; Holgado Tello, Francisco Pablo

    2013-01-01

    Enfrentar las actividades de la vida diaria implica activar procesos atencionales que nos permitan estar más receptivos a los sucesos del ambiente y desempeñarnos en determinadas tareas independientemente del tipo de esfuerzo que ellas supongan. En este contexto, el trabajo tiene como propósito analizar los procesos de atención presentes en el déficit atencional. Los mecanismos implicados pueden ser del tipo selectivo, de distribución y de mantenimiento o sostenimiento. En los alumnos con TDA...

  12. Proceso Editorial de la Revista Científica Ciencia Médica

    OpenAIRE

    Zenia Claros Coca

    2013-01-01

    El proceso editorial es una etapa crucial que tiene como objetivo garantizar la calidad y originalidad científica de los trabajos publicados. La Revista Científica Ciencia Médica logra todo este proceso gracias a un trabajo conjunto del comité editorial y al peer – review realizado por revisores expertos en el tema, los cuales llevan a cabo una revisión crítica y valoran el interés de los trabajos remitidos.

  13. Modelo de proceso de ingeniería de requisitos de software distribuida

    OpenAIRE

    Sevilla, Gustavo; Zapata, Sergio; Torres, Estela; Collazos, César; Giraldo, Fáber

    2016-01-01

    [9 p.] il. Los escenarios de Desarrollo Global de Software, donde los distintos interesados están dispersos geográficamente, crecen a diario en muchas partes del mundo, incluso en Latinoamérica. Este nuevo entorno impacta sobre el desempeño de los métodos y herramientas usadas en procesos de software tradicionales. Debido al alto flujo de comunicación que requiere entre los actores de estos procesos, la fase de ingeniería de requisitos es tal vez la más afectada por las características ...

  14. Análisis estratégico del proceso productivo en el sector industrial

    OpenAIRE

    Guillermo Rodríguez Medina; Solange Balestrini Atencio; Sara Balestrini Atencio; Rosana Meleán Romero; Belkis Rodríguez Castro

    2002-01-01

    Este artículo contiene una reflexión sobre los factores claves de éxito para el análisis estratégico del proceso productivo del sector industrial, cuyo objetivo es tratar aspectos fundamentales para las estrategias de modernización como el diseño de los productos, la selección del sistema productivo y de la tecnología, la planificación de la capacidad, la ubicación y distribución de las instalaciones, el diseño de los procesos, la cadena de valor, el aseguramiento de la calidad, e...

  15. Estudio del proceso constructivo de cimentaciones de gravedad para eólica offshore

    OpenAIRE

    Solana Santillana, Borja

    2015-01-01

    RESUMEN: El objetivo de este proyecto es desarrollar el proceso constructivo de una cimentación de gravedad para eólica offshore. Al igual que en el otro proyecto, “Diseño de Cimentaciones en Gravedad para Eólica Offshore”, tras una revisión del estado del arte, y de los antecedentes existentes, se procede al estudio de los requerimientos de diseño, que pueden condicionar el proceso constructivo. Una vez conocidos los condicionantes y las características geométricas de la cimentación se...

  16. A paz en Colombia: O proceso de paz do goberno de Santos coas FARC-EP

    OpenAIRE

    Cotofre Grela, David

    2017-01-01

    Traballo Fin de Grao en Ciencia Política e da Administración. Curso 2016-2017 Analizase o proceso de paz que se produciu en Colombia nos derradeiros anos (2012 – 2016) e que remataron por desembocar na paz logo de máis de 50 anos de conflito interno. Entenderemos proceso de paz coma un esforzo para lograr un acordo que poña fin á violencia mediante negociacións que poden precisar a mediación de terceiros. Dentro do análise teremos unha especial atención como actor a sociedade civil, ...

  17. Desarrollo de sistemas de apoyo para la toma de decisiones en procesos industriales

    OpenAIRE

    Tarifa, Enrique E.; Martínez, Sergio; Domínguez, Samuel Franco; Núñez, Álvaro; Sánchez Rivero, David

    2011-01-01

    El presente proyecto tiene por objetivo general desarrollar sistemas de apoyo para la toma de decisiones en procesos industriales. Estos sistemas son cada vez más necesarios debido a la complejidad creciente de los escenarios planteados por la globalización, la competencia, los avances tecnológicos, los problemas ambientales y sociales, entre otros. La secuencia de procesos requeridos para tomar decisiones es independiente del área particular de aplicación. Esta secuencia es: 1) Identifica...

  18. Aplicaciones informáticas para soporte de los procesos electorales

    OpenAIRE

    Brossard Castillo, Jaime Alejandro; Brossard Castillo, Jaime Alejandro

    2008-01-01

    Los Procesos Electorales se realizan periódicamente y tienen como finalidad elegir las autoridades que gobernarán los destinos del país a nivel nacional, regional y local. Desde una perspectiva individual, cada elector participa y espera que su voto sea considerado adecuadamente, debiendo depositar su confianza en las Instituciones que administran los procesos que se ejecutan en el Sistema Electoral, siendo el factor tiempo de respuesta de la emisión de los resultados de vital importancia par...

  19. Relevancia e Inferencia: Procesos cognitivos propios de la comunicación humana

    Directory of Open Access Journals (Sweden)

    Constanza Moya Pardo

    2006-06-01

    Full Text Available Este artículo pretende mostrar los planteamientos cognitivos más representativos de la Teoría de la Relevancia propuesta por Spelber & Wilson con respecto al modelo ostensivo-inferencial. Este modelo plantea un mecanismo deductivo explícito que da cuenta de los procesos y estrategias que permiten el paso del significado literal a la interpretación pragmática de los mensajes en el proceso de comunicación humana.

  20. Mejora de proceso de inventario general en una empresa distribuidora de útiles escolares.

    OpenAIRE

    Jáuregui Carruitero, Christian Elti; Jáuregui Carruitero, Christian Elti; Jáuregui Carruitero, Christian Elti

    2012-01-01

    El desarrollo del presente trabajo se enfoca en mejorar el proceso de toma de inventario general en una empresa comercializadora de útiles escolares. Esta mejora influye directamente en el índice de exactitud de inventarios, indicador de gran importancia para diversas áreas de la empresa tales como: Ventas, Contabilidad, Finanzas, Abastecimiento, Distribución, entre otras. En el caso del Área de Contabilidad y Finanzas la información resultante de un proceso de toma de inventarios se utili...

  1. Resultado del proceso educativo: el papel de los estilos de aprendizaje y la personalidad

    OpenAIRE

    Santos Álvarez, María del Valle; Garrido Samaniego, María José

    2015-01-01

    En esta investigación se plantea el análisis del estilo de aprendizaje y la personalidad eficaz en una muestra de estudiantes universitarios y se analiza su posible asociación con las dimensiones de resultado del proceso educativo: rendimiento académico y satisfacción. Los resultados sugieren que el estilo predominante en los participantes es el reflexivo y que existen relaciones entre los distintos estilos. Se constata también que las dos dimensiones del resultado del proceso educativo (rend...

  2. Calidad total en un modelo integrado de proceso software y ciclo de vida

    OpenAIRE

    Mon, Alicia; Garzás, Javier

    2009-01-01

    La modelización del Proceso Software constituye un marco de referencia para la organización de las actividades que involucran todas las etapas del desarrollo. La representación del ciclo de vida define los estados por los que pasa un producto software y la representación del proceso software define el conjunto de actividades esenciales no ordenadas en el tiempo que requiere el desarrollo de software. En el presente artículo se exponen los avances de una investigación que propone una modeli...

  3. Modelos del proceso de educción de requisitos: Un mapeo sistemático

    OpenAIRE

    Dante Carrizo; Cristian Ortiz

    2016-01-01

    La educción es una actividad dentro del proceso de la Ingeniería de Requisitos que recupera información relevante acerca del dominio del problema y de las necesidades de los stakeholders para la conformación de los requisitos del producto software. Para evaluar la efectividad de la educción, es necesario conocer y modelar la influencia del contexto en el cual se desarrolla este proceso. Este artículo presenta el estado del arte sobre la actividad de educción de requisitos, principalmente sobr...

  4. La carga física de los trabajadores: estrategia administrativa en la mejora de procesos

    OpenAIRE

    Real Pérez, Grether Lucía; Hidalgo Ávila, Argelio Antonio; Ramos Alfonso, Yanelis

    2015-01-01

    La administración surge cuando existe la necesidad de manejar recursos. Los administradores deben planificar, organizar, dirigir y controlar todos los elementos de los procesos, considerando los medios de trabajo, los objetos de trabajo y las personas. Este último es el eslabón fundamental del proceso productivo o de servicio. Se debe considerar además el entorno y su relación con el medio ambiente, permitiendo ser a las empresas responsables con los tres pilares fundamentales: la sociedad, e...

  5. Estrategia para el aprendizaje de competencias profesionales en el proceso docente educativo en Ciencias Sociales

    OpenAIRE

    Verónica Guamán Gómez; Enrique Espinoza Freire; Francisco Sánchez Flores

    2017-01-01

    Este trabajo analiza la participación de los individuos en los procesos sociales y su empoderamiento, lo cual constituye tema del debate actual en los ámbitos académico, social, político y cultural; destacándose por todos la necesidad de un individuo emprendedor, capaz de aprovechar las oportunidades y saber hacer cuando el momento así lo requiera. El proceso docente educativo ha de propiciar la adquisición y desarrollo de competencias profesionales para el desempeño en ese entorno social cam...

  6. El Grafeno. Parte II: procesos y viabilidad de su producción

    OpenAIRE

    Mayora Curzio, Carlos A.; Cremades Oliver, Lázaro Vicente; Cusidó Fàbregas, Joan Antoni

    2015-01-01

    Ante el descubrimiento del grafeno, un material con propiedades de gran interés tecnológico, la industria busca optimizar sus mecanismos de producción con el objetivo de abordar un mercado para el cual se prevé un gran crecimiento. La síntesis de grafeno puede llevarse a cabo mediante diversos procesos, si bien para cada uno de ellos se pueden advertir diferencias respecto la calidad del producto final. Entre tales procesos, se distinguen dos grupos: aquellos que parten de átomos de carbono p...

  7. El trabajo independiente en el proceso de enseñanza-aprendizaje

    OpenAIRE

    Soca Guevara, Edelmira Belkis

    2015-01-01

    El trabajo independiente forma parte del proceso de enseñanza aprendizaje y ejerce una importante influencia en la formación del estudiante en cualquier nivel de enseñanza. Una buena planificación del trabajo independiente por parte del profesor contribuye a elevar la calidad del proceso docente. En este trabajo se discute el beneficio de la utilización del formato web como soporte para la propuesta de cursos interactivos y dinámicos confeccionados por los profesores, como apoyo al trabajo in...

  8. Intestinal transport and metabolism of bile acids

    Science.gov (United States)

    Dawson, Paul A.; Karpen, Saul J.

    2015-01-01

    In addition to their classical roles as detergents to aid in the process of digestion, bile acids have been identified as important signaling molecules that function through various nuclear and G protein-coupled receptors to regulate a myriad of cellular and molecular functions across both metabolic and nonmetabolic pathways. Signaling via these pathways will vary depending on the tissue and the concentration and chemical structure of the bile acid species. Important determinants of the size and composition of the bile acid pool are their efficient enterohepatic recirculation, their host and microbial metabolism, and the homeostatic feedback mechanisms connecting hepatocytes, enterocytes, and the luminal microbiota. This review focuses on the mammalian intestine, discussing the physiology of bile acid transport, the metabolism of bile acids in the gut, and new developments in our understanding of how intestinal metabolism, particularly by the gut microbiota, affects bile acid signaling. PMID:25210150

  9. Sexuality of people with intestinal ostomy

    Directory of Open Access Journals (Sweden)

    Danyelle Braga Rodrigues Cardoso

    2015-09-01

    Full Text Available Objective: to describe the experience of sexuality and other everyday life aspects for people with intestinal ostomy. Methods: qualitative, descriptive study with ten participants of the Specialized Reference Unit who gave interviews with inductive content analysis. Results: the established themes were Physical, emotional and socio-cultural changes, Changes in the exercise of sexuality of people with intestinal ostomy and Importance of the interdisciplinary support of the new sexuality. These changes are linked to body image, the self-esteem and interpersonal relationships with the partner, family and friends, going beyond the visible with the emergence of fear, rejection, difficulty with new relationships, body shame, embarrassment by the collector equipment, fear of the sexual act causes damage to the stoma and difficult to talk about the condition. Conclusion: the ostomy condition requires adaptation process, requiring trained interdisciplinary team in physiological and psychosocial problems resulting from surgical and therapeutic adjuvant treatment, which hinder the sexuality of these individuals.

  10. [Intestinal volvulus due to yeyunal duplication].

    Science.gov (United States)

    Rodríguez Iglesias, P; Carazo Palacios, M E; Lluna González, J; Ibáñez Pradas, V; Rodríguez Caraballo, L

    2014-10-01

    Duplications of the alimentary tract are congenital malformations. The ileum is the most commonly affected organ. A lot of duplications are incidentally diagnosed but most of patients present a combination of pain or complications such as obstructive symptoms, intestinal intussusception, perforation or volvulus. We report the case of a 6-years-old girl, with intermittent abdominal pain and vomits for two months long. Laboratory work was completely normal and in the radiology analysis (abdominal sonography and magnetic resonance) a cystic image with intestinal volvulus was observed. The patient underwent laparotomy, Ladd's procedure was done and the cyst was resected. In conclusion, if a patient is admitted with abdominal pain and obstructive symptoms, it is important to consider duplication of the alimentary tract as a possible diagnosis.

  11. Model prodrugs for the intestinal oligopeptide transporter

    DEFF Research Database (Denmark)

    Nielsen, C U; Andersen, R; Brodin, Birger

    2001-01-01

    The human intestinal di/tri-peptide carrier, hPepT1, has been suggested as a target for increasing intestinal transport of low permeability compounds by creating prodrugs designed for the transporter. Model ester prodrugs using the stabilized dipeptides D-Glu-Ala and D-Asp-Ala as pro...... with a pH of approximately 6.0, but still release the model drug at the intercellular and blood pH of approximately 7.4. Even though benzyl alcohol is not a low molecular weight drug molecule, these results indicate that the dipeptide prodrug principle is a promising drug delivery concept. However......, the physico-chemical properties such as electronegativity, solubility, and log P of the drug molecule may also have an influence on the potential of these kinds of prodrugs. The purpose of the present study is to investigate whether the model drug electronegativity, estimated as Taft substitution parameter...

  12. Prophylactic Ozone Administration Reduces Intestinal Mucosa Injury Induced by Intestinal Ischemia-Reperfusion in the Rat

    Directory of Open Access Journals (Sweden)

    Ozkan Onal

    2015-01-01

    Full Text Available Objectives. Intestinal ischemia-reperfusion injury is associated with mucosal damage and has a high rate of mortality. Various beneficial effects of ozone have been shown. The aim of the present study was to show the effects of ozone in ischemia reperfusion model in intestine. Material and Method. Twenty eight Wistar rats were randomized into four groups with seven rats in each group. Control group was administered serum physiologic (SF intraperitoneally (ip for five days. Ozone group was administered 1 mg/kg ozone ip for five days. Ischemia Reperfusion (IR group underwent superior mesenteric artery occlusion for one hour and then reperfusion for two hours. Ozone + IR group was administered 1 mg/kg ozone ip for five days and at sixth day IR model was applied. Rats were anesthetized with ketamine∖xyzlazine and their intracardiac blood was drawn completely and they were sacrificed. Intestinal tissue samples were examined under light microscope. Levels of superoxide dismutase (SOD, catalase (CAT, glutathioneperoxidase (GSH-Px, malondyaldehide (MDA, and protein carbonyl (PCO were analyzed in tissue samples. Total oxidant status (TOS, and total antioxidant capacity (TAC were analyzed in blood samples. Data were evaluated statistically by Kruskal Wallis test. Results. In the ozone administered group, degree of intestinal injury was not different from the control group. IR caused an increase in intestinal injury score. The intestinal epithelium maintained its integrity and decrease in intestinal injury score was detected in Ozone + IR group. SOD, GSH-Px, and CAT values were high in ozone group and low in IR. TOS parameter was highest in the IR group and the TAC parameter was highest in the ozone group and lowest in the IR group. Conclusion. In the present study, IR model caused an increase in intestinal injury.In the present study, ozone administration had an effect improving IR associated tissue injury. In the present study, ozone therapy

  13. Repairing organs: lessons from intestine and liver

    OpenAIRE

    Gehart Helmuth; Clevers Hans

    2015-01-01

    The concept of organ regeneration has fascinated humanity from ancient mythology to modern science fiction. Recent advances offer the potential to soon bring such technology within the grasp of clinical medicine. Rapidly expanding insights into the intrinsic repair processes of the intestine and liver have uncovered significant plasticity in epithelial tissues. Harnessing this knowledge researchers have recently created culture systems that enable the expansion of stem cells into transplantab...

  14. Salmonella Typhimurium infection in the porcine intestine

    DEFF Research Database (Denmark)

    Schauser, Kirsten; Olsen, John Elmerdahl; Larsson, Lars-Inge

    2005-01-01

    The normal intestinal epithelium is renewed with a turnover rate of 3-5 days. During Salmonella infection increased cell loss is observed, possibly as a result of programmed cell death (PCD). We have, therefore, studied the effects of Salmonella Typhimurium infection on three elements involved...... in scattered epithelial cells and the number of positive cells increased with increasing times of exposure to Salmonella (P

  15. The intestinal microbiome of fish under starvation

    OpenAIRE

    Xia, Jun Hong; Lin, Grace; Fu, Gui Hong; Wan, Zi Yi; Lee, May; Wang, Le; Liu, Xiao Jun; Yue, Gen Hua

    2014-01-01

    Background Starvation not only affects the nutritional and health status of the animals, but also the microbial composition in the host’s intestine. Next-generation sequencing provides a unique opportunity to explore gut microbial communities and their interactions with hosts. However, studies on gut microbiomes have been conducted predominantly in humans and land animals. Not much is known on gut microbiomes of aquatic animals and their changes under changing environmental conditions. To add...

  16. Liver Disease Secondary to Intestinal Failure

    Directory of Open Access Journals (Sweden)

    Bassam Abu-Wasel

    2014-01-01

    Full Text Available IFALD is a common and potentially life-threatening condition for patients with SBS requiring long-term PN. There exists the potential for decreasing its incidence by optimizing the composition and the rate of infusion of parenteral solutions, by advocating a multidisciplinary approach, and by early referral for intestinal-liver transplantation to ensure long-term survival of patients with SBS.

  17. Radiobiology of intestinal epithelium stem cells

    International Nuclear Information System (INIS)

    Konoplyannikova, O.A.

    1988-01-01

    After a single or three-fold whole body irradiation of mice with a dose of 4 Gy and the time interval for the proliferation to be restored (5 days or 3 weeks) the survival curve for stem cells of small intestine epithelium with regard to radiation dose was the same as that for non-preirradiated mice. This indicated that the proliferative potential of stem cells in these experimental conditions was not reduced

  18. Behaviour of intestinal lactase after irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Becciolini, A; Cariaggi, P; Gori, A [Florence Univ. (Italy). Istituto di Radiologia

    1975-08-01

    The behavior of intestinal lactase has been studied in rats after irradiation. The significant increase of activity is not immediate, but slowly and progressively starting from 4 hrs after irradiation. The modifications of the activity are slow and gradual also during the reduction phase. This disaccharase does not show a return to normal values even after three weeks. We suggest the hypothesis that the increase could be due to a modification of the normal synthesis of enzymes caused by irradiation.

  19. Protective effects of ischemic postconditioning on intestinal

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    DING Jun-tao

    2011-04-01

    Full Text Available 【Abstract】Objective: To explore the protective effects of two types of ischemic postconditioning (IP on intestinal mucosa barrier in rabbits with crush injury of the hind limb. Methods: This study was conducted between August and December 2008 in the Department of Trauma Surgery, Daping Hospital, Third Military Medical University, Chongqing, China. The model of crush injury to the hind limb of rabbits was firstly developed by a 25 kg object with the right hind limbs fixed by wooden splints, and then two types of IP were established, including occluding/opening the common iliac artery and vein alternatively (traditional IP, IP A and binding/loosening the proximum of the injured hind limb alternatively (modified IP, IP B. Thirty-six male New Zealand white rabbits were randomly divided into three groups: IP A group, IP B group and control group, with 12 rabbits in each group. The serum levels of diamine oxidase (DAO and intestinal fatty acid-binding protein (I-FABP were detected at 2, 6, 12 and 24 hours after injury. Pathological changes of ileum were examined at 24 hours after injury. Results: The serum levels of I-FABP at 2, 6, 12 and 24 hours after injury in both IP A and IP B groups had a significant decrease, compared with control group. DAO levels also showed the same change trend at 2 and 6 hours after injury, but showed no significant difference between two IP groups. No difference in pathological changes of ileum was found among the three groups. Conclusions: IP can protect intestinal mucosa barrier function on the model of hind limb crush injury in rabbits. Meanwhile the modified IP B shows the same protection as the traditional IP A, and is worth applying in clinic. Key words: Ischemic postconditioning; Crush syndrome; Intestinal mucosa

  20. Wine consumption and intestinal redox homeostasis

    Directory of Open Access Journals (Sweden)

    Fiorella Biasi

    2014-01-01

    Wine components have been proposed as an alternative natural approach to prevent or treat inflammatory bowel diseases. The difficulty remains to distinguish whether these positive properties are due only to polyphenols in wine or also to the alcohol intake, since many studies have reported ethanol to possess various beneficial effects. Our knowledge of the use of wine components in managing human intestinal inflammatory diseases is still quite limited, and further clinical studies may afford more solid evidence of their beneficial effects.

  1. Intestinal spirochetosis and colon diverticulosis Espiroquetose intestinal e diverticulose do cólon

    Directory of Open Access Journals (Sweden)

    Marcus Aurelho de Lima

    2005-02-01

    Full Text Available A case of intestinal spirochetosis in a 62-year-old white male is reported. The condition was characterized by chronic flatulence and episodes of intestinal hemorrhage, in addition to the evidence of hypotonic diverticular disease, with a large number of slender organisms in the colon epithelium and cryptae. Spirochetes were demonstrated by Whartin-Starry stain. The serologic tests for syphilis and HIV were positive. Spirochetosis was treated with penicillin G, and the patient remains free of intestinal complaints 20 months later.Um caso de espiroquetose intestinal é relatado em um homem branco de 62 anos. A condição foi caracterizada por flatulência crônica e episódios de hemorragia intestinal, além da evidência de doença diverticular hipotônica dos cólons, com numerosos organismos filamentosos no epitélio e nas criptas do cólon. Os espiroquetas foram demonstrados pela coloração de Whartin-Starry. Os testes sorológicos para sífilis e HIV foram positivos. A espiroquetose foi tratada com penicilina G e o paciente permanece sem queixas intestinais após 20 meses.

  2. [An experimental assessment of methods for applying intestinal sutures in intestinal obstruction].

    Science.gov (United States)

    Akhmadudinov, M G

    1992-04-01

    The results of various methods used in applying intestinal sutures in obturation were studied. Three series of experiments were conducted on 30 dogs--resection of the intestine after obstruction with the formation of anastomoses by means of double-row suture (Albert--Shmiden--Lambert) in the first series (10 dogs), by a single-row suture after V. M. Mateshchuk [correction of Mateshuku] in the second series, and bu a single-row stretching suture suggested by the author in the third series. The postoperative complications and the parameters of physical airtightness of the intestinal anastomosis were studied in dynamics in the experimental animals. The results of the study: incompetence of the anastomosis sutures in the first series 6, in the second 4, and in the third series one. Adhesions occurred in all animals of the first and second series and in 2 of the third series. Six dogs of the first series died, 4 of the second, and one of the third. Study of the dynamics of the results showed a direct connection of the complications with the parameters of the physical airtightness of the anastomosis, and the last-named with the method of the intestinal suture. Relatively better results were noted in formation of the anastomosis by means of our suggested stretshing continuous suture passed through the serous, muscular, and submucous coats of the intestine.

  3. Foreign body-associated intestinal pyogranuloma resulting in intestinal obstruction in four dogs.

    Science.gov (United States)

    Papazoglou, L G; Tontis, D; Loukopoulos, P; Patsikas, M N; Hermanns, W; Kouti, V; Timotheou, T; Liapis, I; Tziris, N; Rallis, T S

    2010-04-17

    Intestinal obstruction resulting from an intramural foreign body-associated pyogranuloma was diagnosed in four dogs. Vomiting and weight loss were the main clinical signs. On physical examination, a mass in the abdomen was detected in three dogs. Abdominal radiography demonstrated the presence of soft tissue opacity in three of the dogs and gas-filled dilated intestinal loops in all four dogs. Abdominal ultrasonography showed hyperkinetic fluid-filled dilated intestinal loops and a hypoechoic small intestinal mass in all the dogs. Exploratory coeliotomy confirmed the presence of a jejunal mass, which was removed by resection and anastomosis in all the dogs. In one of the dogs a linear foreign body was also found cranial to the mass and was removed through a separate enterotomy incision. The lesions were diagnosed as foreign body-associated intestinal pyogranulomas on histological examination. Three dogs recovered without complications, but the fourth showed signs of septic peritonitis four days after surgery and was euthanased at the owner's request. The other three dogs remained disease-free 12 to 42 months after surgery.

  4. Protein synthesis and intestinal flora in piglets

    International Nuclear Information System (INIS)

    Namioka, Shigeo

    1980-01-01

    Utilization of non-protein nitrogen (NPN) by the flora in piglet colon was studied by administration of 15 N-urea and 15 N-ammonium salt to aseptic piglets and to SPF piglets which had been acclimatized to a clean environment after settling of intestinal flora. Administration of 15 N-urea did not result in 15 N uptake by any tissue-constituting protein at any site of the aseptic piglets, almost all 15 N being excreted into the urine. In contrast, the tissue and skeletal muscle of the SPF piglets showed incorporated 15 N from urea. Urea was converted, by urease of the intestinal flora, into NH 3 , which was absorbed from the mucosa of the intestinal tract to reach the liver where it was synthesized into glutamic acid, followed by conversion into various amino acids. 15 N-ammonium administration produced a significant amount of 15 N even in the tissue protein of the aseptic piglets. After NPN administration, the liver protein-constituting amino acid fraction showed 15 N-labeling of almost all essential, as well as non-essential amino acids. Culture of colonic flora with 15 N-urea revealed 15 N-labeling of all amino acids that constituted bacterial cells, indicating the presence of urea recycling mediated by bacterial urease in single rumen animals.(Chiba, N.)

  5. Kiwifruit (Actinidia deliciosa changes intestinal microbial profile

    Directory of Open Access Journals (Sweden)

    Yuan Kun Lee

    2012-06-01

    Full Text Available Background: Kiwifruit is high in pectic polysaccharides and dietary fiber. This study aimed to find out how the ingestion of kiwifruit will affect intestinal microbiota populations, namely Lactobacillus, Bacteroides, Clostridium, Bifidobacterium, and Enterococcus. Methods: Freeze dried kiwifruit (equivalent of two fresh kiwifruits was given to each of the six subjects daily for four days. Faecal samples were collected before, during and after kiwifruit consumption. The faecal bacteria were enumerated by qPCR and RT qPCR methods. Results: The effect of the kiwifruit on intestinal microbiota profile varied between individuals; in general, the kiwifruit demonstrated a prebiotic effect of promoting the content of faecal lactobacilli and bifidobacteria (as compared to the baselines of the same individual before consumption for as long as the fruit was consumed. The effect was however transient, the levels of the two bacteria returned near to that of the baselines upon cessation of consumption. Conclusion: Kiwifruit is a prebiotic in selectively enhancing the growth of intestinal lactic acid bacteria.

  6. Toxic amebic colitis coexisting with intestinal tuberculosis.

    Science.gov (United States)

    Park, S. C.; Jeon, H. M.; Kim, J. S.; Kim, W. W.; Kim, K. W.; Oh, S. T.; Kim, E. K.; Chang, S. K.; Lee, E. J.

    2000-01-01

    A patient with a fulminant amebic colitis coexisting with intestinal tuberculosis had a sudden onset of crampy abdominal pain, mucoid diarrhea, anorexia, fever and vomiting with signs of positive peritoneal irritation. Fulminant amebic colitis occurring together with intestinal tuberculosis is an uncommon event and may present an interesting patho-etiological relationship. The diagnosis was proven by histopathologic examination of resected specimen. Subtotal colectomy including segmental resection of ileum, about 80 cm in length, followed by exteriorization of both ends, was performed in an emergency basis. Despite all measures, the patient died on the sixth postoperative day. The exact relationship of fulminant amebic colitis and intestinal tuberculosis is speculative but the possibility of a cause and effect relationship exists. Fulminant amebic colitis may readily be confused with other types of inflammatory bowel disease, such as idiopathic ulcerative colitis, Crohn's disease, perforated diverticulitis and appendicitis with perforation. This report draws attention to the resurgence of tuberculosis and amebiasis in Korea, and the need for the high degree of caution required to detect it. PMID:11194200

  7. Cholesterol esterase activity of human intestinal mucosa

    International Nuclear Information System (INIS)

    Ponz de Leon, M.; Carubbi, F.; Di Donato, P.; Carulli, N.

    1985-01-01

    It has been suggested that cholesterol absorption in humans is dependent on bile acid pool composition and that expansion of the cholic acid pool size is followed by an increase of the absorption values. Similar observations were reported in rats. In the present study, therefore, the authors investigated some general properties of human intestinal cholesterol esterase, with particular emphasis on the effect of bile acids on this enzymatic activity. Twenty-nine segments of small intestine were taken during operations; the enzymatic activity was studied by using mucosal homogenate as a source of enzyme and oleic acid, cholesterol, and 14 C-labeled cholesterol as substrates. The time-activity relationship was linear within the first two hours; optimal pH for esterification ranged between 5 and 6.2. There was little difference between the esterifying activity of the jejunal and ileal mucosa. Esterification of cholesterol was observed with all the investigated fatty acids but was maximal with oleic acid. Bile acids did not affect cholesterol esterase activity when present in the incubation mixture at 0.1 and 1.0 mM; the enzymatic activity, however, was significantly inhibited when bile acids were added at 20 mM. In conclusion, this study has shown that the human intestinal mucosa possesses a cholesterol esterase activity; at variance with the rat, however, the human enzyme does not seem to be stimulated by trihydroxy bile acids

  8. Bioactivation of Phytoestrogens: Intestinal Bacteria and Health.

    Science.gov (United States)

    Landete, J M; Arqués, J; Medina, M; Gaya, P; de Las Rivas, B; Muñoz, R

    2016-08-17

    Phytoestrogens are polyphenols similar to human estrogens found in plants or derived from plant precursors. Phytoestrogens are found in high concentration in soya, flaxseed and other seeds, fruits, vegetables, cereals, tea, chocolate, etc. They comprise several classes of chemical compounds (stilbenes, coumestans, isoflavones, ellagitannins, and lignans) which are structurally similar to endogenous estrogens but which can have both estrogenic and antiestrogenic effects. Although epidemiological and experimental evidence indicates that intake of phytoestrogens in foods may be protective against certain chronic diseases, discrepancies have been observed between in vivo and in vitro experiments. The microbial transformations have not been reported so far in stilbenes and coumestans. However, isoflavones, ellagitanins, and lignans are metabolized by intestinal bacteria to produce equol, urolithins, and enterolignans, respectively. Equol, urolithin, and enterolignans are more bioavailable, and have more estrogenic/antiestrogenic and antioxidant activity than their precursors. Moreover, equol, urolithins and enterolignans have anti-inflammatory effects and induce antiproliferative and apoptosis-inducing activities. The transformation of isoflavones, ellagitanins, and lignans by intestinal microbiota is essential to be protective against certain chronic diseases, as cancer, cardiovascular disease, osteoporosis, and menopausal symptoms. Bioavailability, bioactivity, and health effects of dietary phytoestrogens are strongly determined by the intestinal bacteria of each individual.

  9. Biotin absorption by distal rat intestine

    International Nuclear Information System (INIS)

    Bowman, B.B.; Rosenberg, I.H.

    1987-01-01

    We used the in vivo intestinal loop approach, with short (10-min) and long (3-h) incubations, to examine biotin absorption in proximal jejunum, distal ileum, cecum and proximal colon. In short-term studies, luminal biotin disappearance from rat ileum was about half that observed in the jejunum, whereas absorption by proximal colon was about 12% of that in the jejunum. In 3-h closed-loop studies, the absorption of 1.0 microM biotin varied regionally. Biotin absorption was nearly complete in the small intestine after 3 h; however, only about 15% of the dose had been absorbed in the cecum and 27% in the proximal colon after 3 h. Independent of site of administration, the major fraction of absorbed biotin was recovered in the liver; measurable amounts of radioactive biotin were also present in kidney and plasma. The results support the potential nutritional significance for the rat of biotin synthesized by bacteria in the distal intestine, by demonstrating directly an absorptive capability of mammalian large bowel for this vitamin

  10. Aryl hydrocarbon receptor and intestinal immunity.

    Science.gov (United States)

    Lamas, Bruno; Natividad, Jane M; Sokol, Harry

    2018-04-07

    Aryl hydrocarbon receptor (AhR) is a member of the basic helix-loop-helix-(bHLH) superfamily of transcription factors, which are associated with cellular responses to environmental stimuli, such as xenobiotics and oxygen levels. Unlike other members of bHLH, AhR is the only bHLH transcription factor that is known to be ligand activated. Early AhR studies focused on understanding the role of AhR in mediating the toxicity and carcinogenesis properties of the prototypic ligand 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). In recent years, however, it has become apparent that, in addition to its toxicological involvement, AhR is highly receptive to a wide array of endogenous and exogenous ligands, and that its activation leads to a myriad of key host physiological functions. In this study, we review the current understanding of the functions of AhR in the mucosal immune system with a focus on its role in intestinal barrier function and intestinal immune cells, as well as in intestinal homeostasis.

  11. Evolutionary insights into postembryonic development of adult intestinal stem cells

    Directory of Open Access Journals (Sweden)

    Ishizuya-Oka Atsuko

    2011-11-01

    Full Text Available Abstract In the adult vertebrate intestine, multi-potent stem cells continuously generate all of the epithelial cells throughout the adulthood. While it has long been known that the frog intestine is formed via the development of adult intestinal stem cells during thyroid hormone (TH-dependent metamorphosis, the basic structure of the adult intestine is formed by birth in mammals and it is unclear if the subsequent maturation of the intestine involves any changes in the intestinal stem cells. Two recent papers showing that B lymphocyte-induced maturation protein 1 (Blimp1 regulates postnatal epithelial stem cell reprogramming during mouse intestinal maturation support the model that adult intestinal stem cells are developed during postembryonic development in mammals, in a TH-dependent process similar to intestinal remodeling during amphibian metamorphosis. Since the formation of the adult intestine in both mammals and amphibians is closely associated with the adaptation from aquatic to terrestrial life during the peak of endogenous TH levels, the molecular mechanisms by which the adult stem cells are developed are likely evolutionally conserved.

  12. Los procesos metacognitivos: La metacomprensión y la actividad de la lectura

    Directory of Open Access Journals (Sweden)

    Alvarado Calderón, Kathia

    2003-12-01

    Full Text Available Este estudio tiene como objetivo describir la relación entre los aspectos comprendidos bajo el nombre de procesos metacognitivos, la metacomprensión y la realización exitosa de la actividad de la lectura. Es ya reconocido que el término ‘metacognición’ designa los trabajos en el dominio de la psicología cognitiva resultado de las investigaciones de J. Flavell, H. Wellman y A. Brown. En las definiciones sobre ‘metacognición’ encontramos una especie de consenso que integra dos vertientes principales. La primera centrada en los conocimientos del sujeto sobre sus procesos cognitivos, la segunda vertiente, la que concierne a la regulación de los procesos cognitivos a través de las estrategias de control de los progresos en un aprendizaje cualquiera. Esta orientación, sin duda, abre posibilidades para el sujeto en términos de aprendizaje de contenidos escolares, pero también y principalmente en relación con su participación como sujeto comprometido activamente con su propio proceso de aprendizaje. Los procesos metacognitivos juegan un papel fundamental en la comprensión del texto y en el recuerdo de eso que ha sido leído. Estos procesos facilitan la comprensión y permiten al lector ajustarse al texto y al contexto. En el proceso de lectura el primer componente de la metacognición comprende los conocimientos que el sujeto lector posee sobre sus procesos cognitivos asociados con la lectura, cuando el sujeto opera desde este conocimiento demuestra que está comprometido en un proceso de investigación, de comprensión y de autoevaluación. El segundo componente es el de la regulación o del control cognitivo en la actividad de la lectura. Los autores reconocen este tipo de conocimiento bajo el nombre de metacomprensión, con dos componentes , el conocimiento de los procesos en tres vías: el lector, la tarea y las estrategias; y la gestión de los procesos cognitivos o comportamientos eficaces para desarrollar sus estrategias de

  13. Los procesos metacognitivos: La metacomprensión y la actividad de la lectura

    Directory of Open Access Journals (Sweden)

    Kathia Alvarado Calderón

    2003-01-01

    Full Text Available Este estudio tiene como objetivo describir teóricamente la relación entre los aspectos comprendidos bajo el nombre de procesos metacognitivos, la metacomprensión y la realización exitosa de la actividad de la lectura en todo sujeto lector. Es ya reconocido que el término ‘metacognición’ designa los trabajos en el dominio de la psicología cognitiva resultado de las investigaciones de J. Flavell, H. Wellman y A. Brown. En las definiciones sobre ‘metacognición’ encontramos una especie de consenso que integra dos vertientes principales. La primera centrada en los conocimientos del sujeto sobre sus procesos cognitivos, la segunda vertiente, la que concierne a la regulación de los procesos cognitivos a través de las estrategias de control de los progresos en un aprendizaje cualquiera. Esta orientación, sin duda, abre posibilidades para el sujeto en términos de aprendizaje de contenidos escolares, pero también y principalmente en relación con su participación como sujeto comprometido activamente con su propio proceso de aprendizaje. Los procesos metacognitivos juegan un papel fundamental en la comprensión del texto y en el recuerdo de eso que ha sido leído. Estos procesos facilitan la comprensión y permiten al lector ajustarse al texto y al contexto. En el proceso de lectura el primer componente de la metacognición comprende los conocimientos que el sujeto lector posee sobre sus procesos cognitivos asociados con la lectura, cuando el sujeto opera desde este conocimiento demuestra que está comprometido en un proceso de investigación, de comprensión y de autoevaluación. El segundo componente es el de la regulación o del control cognitivo en la actividad de la lectura. Los autores reconocen este tipo de conocimiento bajo el nombre de metacomprensión, con dos componentes , el conocimiento de los procesos en tres vías: el lector, la tarea y las estrategias; y la gestión de los procesos cognitivos o comportamientos eficaces

  14. On the occurrence of Obelia medusa blooms and empirical evidence of unusual massive accumulations of Obelia and Amphisbetia hydroids on the Argentina shoreline Bloom de la medusa Obelia y evidencia empírica de una inusual acumulación masiva de hidroides de Obelia y Amphisbetia en la línea de costa en Argentina

    Directory of Open Access Journals (Sweden)

    Gabriel Genzano

    2008-01-01

    Full Text Available Medusa blooms are a scarcely known phenomenon. For temperate, southwestern Atlantic waters, reports of such events are almost nonexistent. This research reports the analysis of a total of 1043 plankton samples taken from 1993 to 2006 and benthic samples collected by seasonal SCUBA diving since 1997 along the Buenos Aires coast. The medusa Obelia longissima was observed in very low densities and frequen-cies, except in October 2003, when a bloom of this species was detected. Soon afterward, two consecutive massive accumulations of O. longissima and Amphisbetia operculata colonies were detected on the coast by the mhabitants of Mar del Plata (38°00'S-57°32'W and the coastal Mar Chiquita Lagoon (37°32'S-57°19'W between March and April 2004. The colonies of both species were collected from the shoreline at low tide at both sites. The environmental factors of that period seemed to be particularly appropriate for promoting optimum growth conditions for these hydroid species. This paper reports and describes the mentioned abnormal phe-nomena, providing baseline information on these little-understood events.Los blooms de medusas son un fenómeno escasamente conocido. En las aguas templadas del Atlántico sudoccidental, esta clase de eventos son casi inexistentes. Un total de 1.043 muestras de plancton de 1993 a 2006 fueron analizadas como también aquellas de bentos colectadas por SCUBA estacionalmente desde 1997 en la costa de Buenos Aires. Para la medusa Obelia longissima fueron observadas muy bajas densidades y frecuencias, con excepción de octubre de 2003 cuando un bloom de esta medusa fue detectado. Seguidamente, dos acumulaciones masivas consecutivas de colonias de O. longissima y de Amphisbetia operculata fueron detectadas sobre la línea de costa por habitantes de Mar del Plata (38°00'S-57°32'W y de la laguna costera Mar Chiquita (37°32'S-57°19'W entre marzo y abril del 2004. Las colonias de ambas especies fueron colectadas desde la l

  15. Innate Lymphoid Cells in Intestinal Inflammation

    Science.gov (United States)

    Geremia, Alessandra; Arancibia-Cárcamo, Carolina V.

    2017-01-01

    Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine that encompasses Crohn’s disease (CD) and ulcerative colitis. The cause of IBD is unknown, but the evidence suggests that an aberrant immune response toward the commensal bacterial flora is responsible for disease in genetically susceptible individuals. Results from animal models of colitis and human studies indicate a role for innate lymphoid cells (ILC) in the pathogenesis of chronic intestinal inflammation in IBD. ILC are a population of lymphocytes that are enriched at mucosal sites, where they play a protective role against pathogens including extracellular bacteria, helminthes, and viruses. ILC lack an antigen-specific receptor, but can respond to environmental stress signals contributing to the rapid orchestration of an early immune response. Several subsets of ILC reflecting functional characteristics of T helper subsets have been described. ILC1 express the transcription factor T-bet and are characterized by secretion of IFNγ, ILC2 are GATA3+ and secrete IL5 and IL13 and ILC3 depend on expression of RORγt and secrete IL17 and IL22. However, ILC retain a degree of plasticity depending on exposure to cytokines and environmental factors. IL23 responsive ILC have been implicated in the pathogenesis of colitis in several innate murine models through the production of IL17, IFNγ, and GM-CSF. We have previously identified IL23 responsive ILC in the human intestine and found that they accumulate in the inflamed colon and small bowel of patients with CD. Other studies have confirmed accumulation of ILC in CD with increased frequencies of IFNγ-secreting ILC1 in both the intestinal lamina propria and the epithelium. Moreover, IL23 driven IL22 producing ILC have been shown to drive bacteria-induced colitis-associated cancer in mice. Interestingly, our data show increased ILC accumulation in patients with IBD and primary sclerosing cholangitis, who carry an increased risk of

  16. Innate Lymphoid Cells in Intestinal Inflammation

    Directory of Open Access Journals (Sweden)

    Alessandra Geremia

    2017-10-01

    Full Text Available Inflammatory bowel disease (IBD is a chronic inflammatory disorder of the intestine that encompasses Crohn’s disease (CD and ulcerative colitis. The cause of IBD is unknown, but the evidence suggests that an aberrant immune response toward the commensal bacterial flora is responsible for disease in genetically susceptible individuals. Results from animal models of colitis and human studies indicate a role for innate lymphoid cells (ILC in the pathogenesis of chronic intestinal inflammation in IBD. ILC are a population of lymphocytes that are enriched at mucosal sites, where they play a protective role against pathogens including extracellular bacteria, helminthes, and viruses. ILC lack an antigen-specific receptor, but can respond to environmental stress signals contributing to the rapid orchestration of an early immune response. Several subsets of ILC reflecting functional characteristics of T helper subsets have been described. ILC1 express the transcription factor T-bet and are characterized by secretion of IFNγ, ILC2 are GATA3+ and secrete IL5 and IL13 and ILC3 depend on expression of RORγt and secrete IL17 and IL22. However, ILC retain a degree of plasticity depending on exposure to cytokines and environmental factors. IL23 responsive ILC have been implicated in the pathogenesis of colitis in several innate murine models through the production of IL17, IFNγ, and GM-CSF. We have previously identified IL23 responsive ILC in the human intestine and found that they accumulate in the inflamed colon and small bowel of patients with CD. Other studies have confirmed accumulation of ILC in CD with increased frequencies of IFNγ-secreting ILC1 in both the intestinal lamina propria and the epithelium. Moreover, IL23 driven IL22 producing ILC have been shown to drive bacteria-induced colitis-associated cancer in mice. Interestingly, our data show increased ILC accumulation in patients with IBD and primary sclerosing cholangitis, who carry an

  17. Neonatal Intestinal Obstruction-Four Year Experience

    Directory of Open Access Journals (Sweden)

    D. Rathore

    2015-06-01

    Full Text Available Aim of study: To study the aetiology and frequency, sex incidence, age of presentation, management and outcome of neonatal intestinal obstruction. Material and Methods: This prospective study of 316 neonates with intestinal obstruction was conducted over a period of 4 years from November 2009 to October 2013 at single institute. These cases were managed by various surgical procedures. Their epidemiology, day of presentation, associated anomalies and outcomes were studied. Results: A total of 316 neonates (277 males and 39 females were operated for intestinal obstruction. 268(84.81% neonates presented in the 1st week of life. Imperforate anus occurred in 206 (65.19%.Small bowel atresia accounted for23 (7.27% cases while duodenal atresia was seen in19 (6.01% patients. Infantile hypertrophic pyloric stenosis and Malrotation each occurred in 14 (4.43% patients; Hirschsprung’s disease in 18(5.69%, Necrotising Enterocolitis in 12(3.79%, Meconium disease of newborn in 9(2.85% while colonic atresia was seen in one (0.3% patient. Colostomy was performed in 145(45.88%, Pouchostomy in 15(4.74% and Cutback anoplasty in 56(17.72% patients. Ramsted’s Pyloromyotomy in 13(4.11%% neonates, Laparoscopic Pyloromyotomy in 1(0.3%,Kimura’s Duodenoduodenostomy in 19(6.01% ,End to Back anastomosis in 24(7.59% , End to End anastomosis in 7(2.21% , Multiple anastomosis in 2(0.6% , Enterotomy with irrigation in 7(2.21% , Ladd’s procedure in 14(4.43% , ,Single stage transanal pull through in 8(2.53% , Ileostomy in 2(0.6% , Single stage Abdominoperineal pull through in 2(0.6%, Levelling colostomy in 6(1.89% ,Peritoneal drain insertion under Local anaesthesia in 5(1.58% . Overall mortality was 13.60%. Conclusion: Intestinal Obstruction is the most common surgical emergency in neonatal period. Early and accurate diagnosis is paramount for proper patient management. The etiology, mode of presentation, morbidity and outcome of surgery of intestinal obstruction in

  18. The Effect of DA-6034 on Intestinal Permeability in an Indomethacin-Induced Small Intestinal Injury Model.

    Science.gov (United States)

    Kwak, Dong Shin; Lee, Oh Young; Lee, Kang Nyeong; Jun, Dae Won; Lee, Hang Lak; Yoon, Byung Chul; Choi, Ho Soon

    2016-05-23

    DA-6034 has anti-inflammatory activities and exhibits cytoprotective effects in acute gastric injury models. However, explanations for the protective effects of DA-6034 on intestinal permeability are limited. This study sought to investigate the effect of DA-6034 on intestinal permeability in an indomethacin-induced small intestinal injury model and its protective effect against small intestinal injury. Rats in the treatment group received DA-6034 from days 0 to 2 and indomethacin from days 1 to 2. Rats in the control group received indomethacin from days 1 to 2. On the fourth day, the small intestines were examined to compare the severity of inflammation. Intestinal permeability was evaluated by using fluorescein isothiocyanate-labeled dextran. Western blotting was performed to confirm the association between DA-6034 and the extracellular signal-regulated kinase (ERK) pathway. The inflammation scores in the treatment group were lower than those in the control group, but the difference was statistically insignificant. Hemorrhagic lesions in the treatment group were broader than those in the control group, but the difference was statistically insignificant. Intestinal permeability was lower in the treatment group than in the control group. DA-6034 enhanced extracellular signal-regulated kinase expression, and intestinal permeability was negatively correlated with ERK expression. DA-6034 may decrease intestinal permeability in an indomethacin-induced intestinal injury model via the ERK pathway.

  19. Kaiso overexpression promotes intestinal inflammation and potentiates intestinal tumorigenesis in Apc(Min/+) mice.

    Science.gov (United States)

    Pierre, Christina C; Longo, Joseph; Mavor, Meaghan; Milosavljevic, Snezana B; Chaudhary, Roopali; Gilbreath, Ebony; Yates, Clayton; Daniel, Juliet M

    2015-09-01

    Constitutive Wnt/β-catenin signaling is a key contributor to colorectal cancer (CRC). Although inactivation of the tumor suppressor adenomatous polyposis coli (APC) is recognized as an early event in CRC development, it is the accumulation of multiple subsequent oncogenic insults facilitates malignant transformation. One potential contributor to colorectal carcinogenesis is the POZ-ZF transcription factor Kaiso, whose depletion extends lifespan and delays polyp onset in the widely used Apc(Min/+) mouse model of intestinal cancer. These findings suggested that Kaiso potentiates intestinal tumorigenesis, but this was paradoxical as Kaiso was previously implicated as a negative regulator of Wnt/β-catenin signaling. To resolve Kaiso's role in intestinal tumorigenesis and canonical Wnt signaling, we generated a transgenic mouse model (Kaiso(Tg/+)) expressing an intestinal-specific myc-tagged Kaiso transgene. We then mated Kaiso(Tg/+) and Apc(Min/+) mice to generate Kaiso(Tg/+):Apc(Min/+) mice for further characterization. Kaiso(Tg/+):Apc(Min/+) mice exhibited reduced lifespan and increased polyp multiplicity compared to Apc(Min/+) mice. Consistent with this murine phenotype, we found increased Kaiso expression in human CRC tissue, supporting a role for Kaiso in human CRC. Interestingly, Wnt target gene expression was increased in Kaiso(Tg/+):Apc(Min/+) mice, suggesting that Kaiso's function as a negative regulator of canonical Wnt signaling, as seen in Xenopus, is not maintained in this context. Notably, Kaiso(Tg/+):Apc(Min/+) mice exhibited increased inflammation and activation of NFκB signaling compared to their Apc(Min/+) counterparts. This phenotype was consistent with our previous report that Kaiso(Tg/+) mice exhibit chronic intestinal inflammation. Together our findings highlight a role for Kaiso in promoting Wnt signaling, inflammation and tumorigenesis in the mammalian intestine. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. Implementación del proceso de canal verde en la aduana marítima de Guayaquil

    OpenAIRE

    Celi Chamba, Johanna Paola

    2008-01-01

    propone un nuevo proceso para facilitar el comercio exterior y de manera en especial las actividades de importación; este proceso denominado Canal Verde o Aforo Automático está siendo aplicando en la mayoría de las aduanas del mundo logrando crear aduanas eficientes

  1. Los Procesos Electorales Centroamericanos en la Década de los 80

    Directory of Open Access Journals (Sweden)

    Fernando HARTO DE VERA

    2009-11-01

    Full Text Available RESUMEN: En este artículo se traza cuales han sido los resultados de los distintos procesos electorales que han tenido lugar durante la década de los ochenta en Centroamérica.ABSTRACT: In this article, the author describes the electoral results of the elections in Central America in the eighties.

  2. Evaluación del Proceso Consultivo Ciudadano en Villa el Salvador, Lima, Peru

    NARCIS (Netherlands)

    J. Calderon (Julio); L. Marulanda (Liliana)

    2001-01-01

    textabstractEl presente informe contiene un estudio de caso sobre “Evaluación del Proceso Consultivo Ciudadano en Villa el Salvador, Lima, Perú” realizado para el Instituto de Estudios de Vivienda y Desarrollo Urbano - IHS (Institute for Housing and Urban Development Studies) y el Programa SINPA

  3. A Failed Utopia in Marcela Del Río's "Proceso a Faubritten"

    Science.gov (United States)

    Manickam, Samuel

    2014-01-01

    In Marcela del Río's science fiction novel "Proceso a Faubritten," utopia comes in the form of eternal life for all of humanity, thanks to Dr. Alexander Faubritten's "Bomba L." This polyphonic work includes diaries by Faubritten and his Mexican lover, María Corona. In my analysis of these two diaries, I will show how…

  4. Análisis estratégico del proceso productivo en el sector industrial

    Directory of Open Access Journals (Sweden)

    Guillermo Rodríguez Medina

    2002-01-01

    Full Text Available Este artículo contiene una reflexión sobre los factores claves de éxito para el análisis estratégico del proceso productivo del sector industrial, cuyo objetivo es tratar aspectos fundamentales para las estrategias de modernización como el diseño de los productos, la selección del sistema productivo y de la tecnología, la planificación de la capacidad, la ubicación y distribución de las instalaciones, el diseño de los procesos, la cadena de valor, el aseguramiento de la calidad, el sistema de producción justo a tiempo, la gestión de inventarios, de los recursos humanos y de los sistemas de información. Estos factores fueron examinados a través de una revisión bibliográfica, cuyo resultado permitió contrastar diferentes autores, analizar y sistematizar los procesos conceptuales relevantes para garantizar el éxito potencial sostenido del proceso productivo en las dimensiones del tiempo de las diversas organizaciones, en la búsqueda de maximizar la eficiencia y el aumento de la productividad.

  5. Retos de la ingeniería industrial en el desarrollo de procesos

    Directory of Open Access Journals (Sweden)

    Oscar Fernando Castellanos

    2002-05-01

    Full Text Available En las diferentes especialidades de la ingeniería, tales como: ambiental, química, sanitaria, mecánica, de alimentos, etc., ha estado presente el diseño de procesos. En la actualidad, la ingeniería de procesos ha tenido que complementarse con conceptos aparentemente ajenos a su visión tradicional. donde se consideraba principalmente la productividad, el rendimiento y la rentabilidad, entre otros; es decir, eran muy importantes los objetivos de la empresa. Sin embargo, con el surgimiento de nuevas tecnologías, como las telecomunicaciones, la ingeniería de nuevos materiales, la biotecnología, entre otras, se hace indispensable considerar enfoques novedosos en el diseño de procesos, tales como reingeniería, ingeniería inversa e ingeniería concurrente, los cuales están llamados a complementar el enfoque tradicional. Adicionalmente, las exigencias de un mercado fuertemente cambiante por las megatendencias de la globalización, la alta competitividad y la normatividad en cuanto al impacto social y ambiental principalmente (ejemplo: BPM - Buenas Prácticas de Manufactura, Normas ISO. plantean nuevos retos en el diseño de los procesos.

  6. Narrativas de la corporeidad en ciclistas colombianos durante su proceso formativo

    Directory of Open Access Journals (Sweden)

    Javier Anzola-Moreno

    2016-09-01

    Full Text Available Introducción. El cambio de paradigmas del cuerpo en el deporte, del cuerpo máquina al embodiment del deportista, requiere comprender el cuerpo vivido, la experiencia encarnada del ciclista, durante su proceso formativo. Objetivo. Comprender el sentido y significado de la corporeidad de ciclistas profesionales colombianos durante su proceso formativo. Materiales y métodos. El estudio fue cualitativo de tipo histórico-hermenéutico, por medio de biografía con entrevista abierta a cuatro ciclistas profesionales colombianos, tres hombres y una mujer nacidos entre 1987 y 1990. Se utilizó el software Atlas Ti 7.0. La categoría principal de análisis fue el embodiment desde las potencialidades y los desgastes. Resultados. Se identificaron potencialidades y desgastes en la corporeidad de los ciclistas durante el proceso formativo. Las categorías relacionadas con la corporeidad de los ciclistas fueron: historicidad del proceso formativo, soporte, orientación, entorno, causas y efectos. El sistema categorial permitió identificar las tendencias, relacionar las categorías e interpretar la corporeidad como expresión del cuerpo vivido. Conclusión. La corporeidad narrada significa la vida de los ciclistas y da sentido a sus vivencias en la identidad del cuerpo ciclista. Se debe reconocer el cuerpo vivido como expresión única de lo humano en movimiento y su abordaje desde la determinación social.

  7. Museo de los desplazados. Archivo de procesos de gentrificación

    Directory of Open Access Journals (Sweden)

    Colectivo Left Hand Rotation

    2016-01-01

    Full Text Available El Museo de los Desplazados es una plataforma de colaboración creada por el Colectivo Left Hand Rotation que surge como conclusión del proyecto - taller “Gentrificación No es un Nombre de Señora” en el que se analiza el papel de la cultura en los procesos de gentrificación. El Museo de los Desplazados es un archivo de material de registro de todo aquello que se pierde en los procesos de gentrificación (vídeo, foto, sonido, esquemas de información y de acciones que impliquen documentación de los procesos de gentrificación y/o acercamiento de la información e interrelación con los perfiles potencialmente en peligro de ser desplazados por procesos de gentrificación. Museo de los Desplazados is a platform created by the Collective Left Hand Rotation arising as completion of the project - workshop “Gentrificación No es un Nombre de Señora” which discusses the role of culture in the processes of gentrification. Museo de los Desplazados is an attempt to record all that is lost to gentrification (video, picture, sound, layout information and actions that involve documentation of gentrification and interaction with profiles potentially in danger of being displaced by gentrification.

  8. Reflexiones comparativas sobre el proceso de modernización en España

    OpenAIRE

    López-Casero, Francisco; Waldmann, Peter

    1994-01-01

    Reflexiones comparativas sobre el proceso de modernización en España / Francisco López-Casero ; Peter Waldmann. - In: El precio de la modernización / Francisco López-Casero ... (comp.). - Frankfurt am Main : Vervuert, 1994. - S. 13-40

  9. El proceso constitucional boliviano: dos visiones de país

    Directory of Open Access Journals (Sweden)

    Miguel A. Buitrago

    2014-06-01

    Full Text Available Reflexión a  propósito del proceso constitucional iniciado por el presidente de Bolivia, Evo Morales, con un discurso el 22 de enero de 2006, en el cual se pretendía incluir a todos los grupos sociales y étnicos que habitaran el país para refundar la identidad boliviana.

  10. ¿El proceso de enfermería hace parte de la calidad del cuidado?

    Directory of Open Access Journals (Sweden)

    MYRIAM ABAUNZA DE GONZÁLEZ

    2007-12-01

    Full Text Available El principal propósito de este artículo es dar respuesta al siguiente interrogante: ¿El proceso de enfermería hace parte de la calidad del cuidado? Para sustentar la respuesta a la pregunta, se parte de referenciar varios autores que han hecho estudios sobre la utilización del método científico, del método de solución de problemas y del proceso de atención de enfermería y su relación con la calidad del servicio y del cuidado de enfermería, al mismo tiempo que se introducen experiencias relacionadas con proyectos de investigación tipo NIPE y Grupos relacionados con el Dx, y experiencias de evaluación de servicios de enfermería en algunos hogares y hospitales en Colombia, México, Cuba y Chile, en donde se aprecia que el proceso de enfermería es el que define el concepto enfermero aplicado. Se concluye que el proceso de enfermería como parte fundamental del cuidado de enfermería, al acortar estancias, disminuir el número de complicaciones y evitar los reingresos, contribuye a mejorar la calidad de su servicio y la calidad de vida de los pacientes/usuarios.

  11. El lenguaje no verbal: un proceso cognitivo superior indispensable para el ser humano

    OpenAIRE

    Corrales Navarro, Elizabeth

    2013-01-01

    El lenguaje no verbal ha sido vital para la conservación y evolución de nuestra especie. El presente artículo recopila datos sobre la importancia evolutiva del lenguaje no verbal para el homo sapiens sapiens, y explica que sin este importante proceso cognitivo, no hubiera sido posible el paso hacia el lenguaje verbal.

  12. El arte en un acto sensible: El niño en procesos creativos

    Directory of Open Access Journals (Sweden)

    Sandra Yaneth Chaparro Cardozo

    2018-01-01

    Full Text Available El presente artículo indaga entorno a los procesos artísticos y su incidencia en la formación de la creatividad, y surge como parte del proyecto Escuela y Creatividad: Estrategias y Fomento de la Facultad de Ciencias de la Educación y Humanidades de la Fundación Universitaria Juan de Castellanos de Tunja, Boyacá. En este estudio se revisaron algunas relaciones entre el arte y la creatividad, partiendo de la observación e interpretación de las intervenciones pictóricas de los niños. Lo que conllevó al siguiente interrogante: ¿Qué tipo de procesos artísticos se desarrollan en la infancia y cómo se articulan con los procesos creativos? Esta investigación se orientó a partir del estudio de casos y tiene por objetivo determinar prácticas artísticas que se desarrollan en la infancia y su articulación en el desarrollo de procesos creativos en niños y niñas. De igual forma se realizó un reconocimiento inicial de la concepción de las artes y la plástica frente a la creatividad, y de la capacidad creadora y artística en la infancia.

  13. Automatización de procesos de control de calidad en sofware industrial

    OpenAIRE

    Carmona Sanz, Artur

    2017-01-01

    Elaborate a procedure for quality assurance processes automation in industrial software Elaboración de un procedimiento para la automatización de procesos de control de calidad en software industrial Elaboració d'un procedimient per l'automatizació de processos de control de qualitat en software industrial

  14. Impacto del proceso de liofilización en la calidad de las fresas

    Directory of Open Access Journals (Sweden)

    Mahacine Amrani

    2007-05-01

    Full Text Available Este trabajo expone el análisis y la modelación cinética de la deshidratación de las fresas enteras y por sec-ciones, durante el proceso de la liofilización. Fue utilizado un liofilizador Virtis 35L Gardiner. La liofilización se realizó a varias temperaturas de la plancha y para varios gruesos de producto, observándose que el aumento en la temperatura del plato de 30 a 70°C en el curso de la liofilización reduce la duración de este proceso en el caso de las fresas enteras de 48h a 36h y de 12h a 8h en el caso de las secciones, para obtener productos secos estables. El estudio del impacto de diferentes parámetros de la liofilización de las fresas demuestra que la temperatura tiene una incidencia importante en la reducción de la duración del proceso. Esto hace bajar los costos del proceso mientras se preserva la calidad de la fruta seca, abriendo así con el uso de esta tecnología el campo en el tratamiento de los productos alimenticios nuevos.

  15. Linfangiectasia intestinal e linfangite lipogranulomatosa em dois caninos Intestinal lymphangiectasia with lipogranulomatous lymphangitis in two dogs

    Directory of Open Access Journals (Sweden)

    Marcia Regina da Silva Ilha

    2004-08-01

    Full Text Available Relatam-se dois casos adicionais de linfangiectasia intestinal e linfangite lipogranulomatosa (LI/LL em caninos. Sinais clínicos manifestados pelos animais afetados incluíam diarréia crônica, perda de peso, dificuldade respiratória e anorexia. À necropsia, a mucosa do intestino delgado apresentava-se pálida, macia e com aspecto aveludado mais evidente conferido por vilosidades esbranquiçadas, alongadas, mais visíveis e densamente aglomeradas formando tufos. Na borda mesentérica da serosa intestinal, havia lesões arredondadas, lisas, elevadas, firmes, brancacentas, de 1-3mm de diâmetro, que também acompanhavam os vasos linfáticos mesentéricos que estavam salientes e distendidos por material espesso e esbranquiçado. Carcaças em mau estado corporal, edema subcutâneo e efusões cavitárias também foram observados. Microscopicamente, havia acentuada ectasia dos vasos quilíferos das vilosidades intestinais associada à presença de lipogranulomas intramurais ou mesentéricos. No presente estudo, o diagnóstico definitivo de LI/LL foi realizado através do exame histológico do intestino delgado e mesentério associado. Desconhece-se a prevalência dessa enfermidade em caninos no Brasil.Two additional cases of intestinal lymphangiectasia with lipogranulomatous lymphangitis (IL/LL in dogs are described. Clinical signs in the affected animals included chronic diarrhea, weight loss, labored breathing and anorexia. At necropsy, the mucosa of the small intestine was pale, soft and had numerous white, elongated villi clumped together in tufts giving the surface of the intestinal mucosa a pronounced velvety pattern. White, round, smooth, raised, firm, pinpoint lesions, varying from 1-3mm of diameter, were observed on the serosal surface of the small intestine on its mesenteric border and along prominent mesenteric lymphatic vessels distended with thick, chalky white paste. Thin carcasses. subcutaneous edema and cavitary effusions were also

  16. Intestinal Stem Cell Niche: The Extracellular Matrix and Cellular Components

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    Laween Meran

    2017-01-01

    Full Text Available The intestinal epithelium comprises a monolayer of polarised columnar cells organised along the crypt-villus axis. Intestinal stem cells reside at the base of crypts and are constantly nourished by their surrounding niche for maintenance, self-renewal, and differentiation. The cellular microenvironment including the adjacent Paneth cells, stromal cells, smooth muscle cells, and neural cells as well as the extracellular matrix together constitute the intestinal stem cell niche. A dynamic regulatory network exists among the epithelium, stromal cells, and the matrix via complex signal transduction to maintain tissue homeostasis. Dysregulation of these biological or mechanical signals could potentially lead to intestinal injury and disease. In this review, we discuss the role of different intestinal stem cell niche components and dissect the interaction between dynamic matrix factors and regulatory signalling during intestinal stem cell homeostasis.

  17. Factors influencing physiological FDG uptake in the intestine

    International Nuclear Information System (INIS)

    Yasuda, Seiei; Takahashi, Wakoh; Takagi, Shigeharu; Fujii, Hirofumi; Ide, Michiru; Shohtsu, Akira

    1998-01-01

    The intestine is a well-known site of physiological 18 F-fluorodeoxyglucose (FDG) accumulation in positron emission tomography (PET). To identify factors influencing physiological FDG uptake in the intestine, the intensity of FDG uptake was evaluated in a total of 1,068 healthy adults. Non-attenuation-corrected whole-body PET images were obtained for all subjects and visually evaluated. Subjects were then classified into two groups according to the intensity of intestinal FDG uptake. Sex, age, presence or absence of constipation, and serum glucose, hemoglobin A 1 c, and free fatty acid levels were compared between the two groups. High intestinal FDG uptake was observed at an overall rate of 11.0%. Sex (female), age, and bowel condition (constipation) were found to affect intestinal FDG uptake. The factors we identified lead to further questions the relationship between intestinal motility and glucose uptake that warrant further study. (author)

  18. Ultrasonography of small intestinal obstructions: a contemporary approach.

    Science.gov (United States)

    Garcia, D A A; Froes, T R; Vilani, R G D O C; Guérios, S D; Obladen, A

    2011-09-01

    To assess the accuracy of intestinal ultrasound for diagnosis of intestinal obstruction in dogs and cats. A prospective clinical study was performed. Inclusion criteria were dogs and cats with clinical signs suggestive of gastrointestinal obstruction. Animals with no obstruction detected on ultrasound were excluded if they could not be monitored for 48 hours to confirm absence of obstruction. Sonographic diagnosis of small intestinal obstruction was based on identification of at least two findings suggestive of intestinal obstruction. Ninety-two patients suspected of having intestinal obstruction were included. Correct diagnosis of intestinal obstruction was made in 21 cases (23%), and in 68 (74%) this diagnosis was excluded. Interpretation of the images on prospective analysis had sensitivity, positive predictive, specificity and negative predictive values of 100%, 87.5%, 95.8% and 100%, respectively. Ultrasonography is an excellent method for investigation of animals with gastrointestinal disorders, and is particularly useful for excluding obstructive processes. © 2011 British Small Animal Veterinary Association.

  19. CT diagnosis of concealed rupture of intestine following abdominal trauma

    International Nuclear Information System (INIS)

    Ji Jiansong; Wei Tiemin; Wang Zufei; Zhao Zhongwei; Tu Jianfei; Fan Xiaoxi; Xu Min

    2009-01-01

    Objective: To investigate CT findings of concealed rupture of intestine following abdominal trauma. Methods: CT findings of 11 cases with concealed rupture of intestine following abdominal trauma proved by surgery were identified retrospectively. Results: The main special signs included: (1) Free air in 4 cases, mainly around injured small bowel or under the diaphragm, or in the retroperitoneal space or and in the lump. (2) High density hematoma between the intestines or in the bowel wall (4 cases). (3) Bowel wall injury sign, demonstrated as low density of the injured intestinal wall, attenuated locally but relatively enhanced in neighbor wall on enhanced CT. (4) Lump around the injured bowel wall with obvious ring-shaped enhancement (4 cases). Other signs included: (1) Free fluid in the abdominal cavity or between the intestines with blurred borders. (2) Bowel obstruction. Conclusion: CT is valuable in diagnosing concealed rupture of intestine following abdominal trauma. (authors)

  20. PROCESOS Y PROCEDIMIENTOS DE ORIENTACIÓN VOCACIONAL / PROFESIONAL / LABORAL DESDE UNA PERSPECTIVA SISTÉMICA

    Directory of Open Access Journals (Sweden)

    Ana Elvira Castañeda Cantillo

    2005-01-01

    Full Text Available Esta investigación buscó hacer una descripción de las comprensiones, estrategias y prácticas que identifican el proceso de orientación vocacional / profesional / laboral en la familia y la escuela. Para ello se identificaron los niveles de participación de cada uno de los actores de la organización escolar: estudiantes, docentes, orientadores y padres de familia, se evaluó el impacto de los procesos de orientación profesional, especificando las acciones que se realizan para ello y el papel de los profesionales que lideran el proceso de orientación vocacional / profesional / laboral en las organizaciones escolares. Mediante un estudio de tipo descriptivo, se aplicó como instrumento una encuesta a orientadores, estudiantes, docentes y padres de familia; las categorías a evaluar fueron: prácticas y nivel de participación en el proceso de orientación, comprensiones y puntuaciones sobre la orientación vocacional / profesional / laboral, efectos e impactos de la orientación, valoración del proceso de orientación, fuentes de influencia en el joven, valoración y recomendaciones de actividades de orientación. Con una muestra de 70 docentes, 35 orientadores, 130 padres de familia y 150 estudiantes de 35 colegios de Bogotá. Se encontró que los procesos y procedimientos realizados en la orientación vocacional / profesional / laboral están relacionados con presupuestos y acciones fundamentalmente dirigidas a la toma de decisión del estudiante sobre la elección de una carrera universitaria, desde sus intereses individuales, factores económicos e información sobre la oferta; no se observa que haya un acompañamiento para la movilización de los sistemas y contextos familiares, escolares y amplios que involucren procesos pedagógicos, psicológicos, sociales y culturales de los jóvenes con la escuela, la familia y el desarrollo del país.