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Sample records for international diabetes federation

  1. INTERNATIONAL DIABETES FEDERATION CONSENSUS ON DEFINITION OF THE METABOLIC SYNDROME: FACTS AND COMMENTS

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    M. N. Mamedov

    2009-01-01

    Full Text Available International Diabetes Federation consensus, devoted to definition of the metabolic syndrome was published in 2006. The main statements of this document are presented and commented.

  2. Prevalence of metabolic syndrome at age 16 using the International Diabetes Federation paediatric definition.

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    Pirkola, J; Tammelin, T; Bloigu, A; Pouta, A; Laitinen, J; Ruokonen, A; Tapanainen, P; Järvelin, M-R; Vääräsmäki, M

    2008-11-01

    We estimated the prevalence of metabolic syndrome (MS) in adolescents, using the new International Diabetes Federation (IDF) paediatric definition and compared this with prevalence estimated using the IDF adult definition and five other previously published definitions. Cross-sectional survey in the prospective general population-based Northern Finland Birth Cohort 1986 (NFBC 1986) at age 16 years. Birth cohort in Finland. 5665 adolescents (2862 males and 2803 females) clinically examined in 2001-2002. The prevalence of MS using different definitions. The overall prevalence of MS using the IDF paediatric definition was 2.4% (95% CI 2.0 to 2.8%) at the age of 16 years. Using the IDF adult definition the overall prevalence was lower, 1.7% (CI 1.3 to 2.0%, European cut-offs for waist circumference) and 1.0% (CI 0.7 to 1.3%, North American cut-offs). In 16-year-old adolescents, the paediatric IDF definition rendered a higher prevalence estimate than the adult definition.

  3. Probable blind spot in the International Diabetes Federation definition of metabolic syndrome.

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    Chen, Hsin-Jen; Pan, Wen-Harn

    2007-05-01

    The International Diabetes Federation (IDF) proposed a novel definition of the metabolic syndrome (MS) in 2005, which designated central obesity as mandatory. The new National Cholesterol Education Program (NCEP) version, announced by the American Heart Association and National Heart Lung and Blood Institute in October 2005, did not favor any of the five components. We set out to compare the cardiovascular profiles of patients cross-defined by these two definitions to shed light on the differential meanings of the two. We analyzed data from 2608 non-institutionalized adults (> or =19 years old) in the National Nutrition and Health Survey in Taiwan, who had complete data for the five MS defining components. Both definitions adopted lower cut-points for fasting glucose and race-specific cut-points for waist circumference. Under the IDF's and new NCEP's definitions, the MS prevalence was 6.2% and 11.6% in men and 12.6% and 16.5% in women, respectively. Although the two definitions had high agreement, IDF failed to pick up approximately 4% to 5% of people with more than three MS component disorders but a waist circumference less than the cut-point. Subjects whose physical conditions only satisfied NCEP's definition had similar or worse metabolic profiles than those whose conditions satisfied both IDF's definition and the new NCEP's definition. The IDF definition would fail to identify a portion of people who have more than three MS component disorders but a small waistline. Further research and discussion are needed on whether and how to implement the IDF's definition.

  4. Prevalence of metabolic syndrome in urban and suburban Rivers State, Nigeria: International Diabetes Federation and Adult Treatment Panel III definitions.

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    Siminialayi, I M; Emem-Chioma, P C; Odia, O J

    2010-06-01

    It was not clear for a while, which of the definitions of metabolic syndrome best predicted those at risk of cardiovascular disease and diabetes but recent studies have confirmed the predictive ability of various definitions of metabolic syndrome and have reported that the International Diabetes Federation definition, although more sensitive is associated with a higher false positive predictive rate. To determine the prevalence of metabolic syndrome, using the International Diabetes Federation and Adult Treatment Panel III definitions among adult Nigerians attending Family Medicine Clinics at two hospitals in Rivers State Nigeria. Adult subjects attending family medicine clinics at an urban and a sub-urban hospital in Rivers State, Nigeria were bled after an overnight fast, and venous blood obtained for lipid studies and fasting plasma glucose estimations. Measurements were made to determine height, weight, waist circumference and blood pressure. The data obtained was analysed using SPSS for Windows software version 12 and Epi info version 6.04D RESULTS: The prevalence of metabolic syndrome was 19.81% (ATP III) and 23.19% (IDF) at one centre and 34.17% (ATP III) and 35.42% (IDF) at the other centre. The prevalence of metabolic syndrome by the two definitions was significantly higher at the second centre. The difference in the prevalence rates by the two definitions was also much smaller in the second centre perhaps because the second centre had more women and the mean age of the subjects was significantly higher.

  5. National Cholesterol Education Program and International Diabetes Federation definitions of metabolic syndrome in the prediction of diabetes. Results from the FIrenze-Bagno A Ripoli study.

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    Mannucci, E; Monami, M; Cresci, B; Pala, L; Bardini, G; Petracca, M G; Dicembrini, I; Pasqua, A; Buiatti, E; Rotella, C M

    2008-05-01

    The International Diabetes Federation (IDF) proposed to modify the diagnostic criteria for metabolic syndrome (MS) previously issued by the National Cholesterol Education Program (NCEP). Aim of the present investigation is to compare the predictive value for diabetes of NCEP and IDF definitions of MS in a large sample of predominantly Caucasian subjects. A prospective observational study was performed on a cohort study (n = 3096) enrolled in a diabetes-screening programme, the FIrenze-Bagno A Ripoli study. All subjects with fasting glucose >126 mg/dl and/or post-load glucose > or =200 mg/dl (5.7%) were excluded from the present analysis. Follow-up of each subject was continued until diagnosis of diabetes, death or until 31 December 2005. Mean follow-up was 27.7 +/- 11.3 months. Among subjects enrolled, 13.7 and 25.2% were affected by MS using NCEP and IDF criteria respectively. During follow-up, 38 new cases of diabetes were diagnosed, with a yearly incidence rate of 0.5%. The relative risk for diabetes in subjects with MS was 10.10 [5.13; 20.00] and 7.87 [3.70; 16.7] using NCEP and IDF definitions respectively. After adjustment for age, sex, fasting glucose and waist circumference, NCEP-defined MS, but not IDF-, was significantly associated with incident diabetes (hazard ratio, 95% CI: 2.41 [1.01; 5.95] and 2.05 [0.80; 5.29] respectively). Although the reasons for the proposed changes in diagnostic criteria for MS are easily understandable, the newer IDF definition, while increasing estimates of prevalence of the syndrome, reduces the effectiveness of MS in identifying subjects at risk for diabetes. Further research is needed before the previous NCEP criteria are abandoned.

  6. Comparison of type 2 diabetes prevalence estimates in Saudi Arabia from a validated Markov model against the International Diabetes Federation and other modelling studies

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    Al-Quwaidhi, Abdulkareem J.; Pearce, Mark S.; Sobngwi, Eugene; Critchley, Julia A.; O’Flaherty, Martin

    2014-01-01

    Aims To compare the estimates and projections of type 2 diabetes mellitus (T2DM) prevalence in Saudi Arabia from a validated Markov model against other modelling estimates, such as those produced by the International Diabetes Federation (IDF) Diabetes Atlas and the Global Burden of Disease (GBD) project. Methods A discrete-state Markov model was developed and validated that integrates data on population, obesity and smoking prevalence trends in adult Saudis aged ≥25 years to estimate the trends in T2DM prevalence (annually from 1992 to 2022). The model was validated by comparing the age- and sex-specific prevalence estimates against a national survey conducted in 2005. Results Prevalence estimates from this new Markov model were consistent with the 2005 national survey and very similar to the GBD study estimates. Prevalence in men and women in 2000 was estimated by the GBD model respectively at 17.5% and 17.7%, compared to 17.7% and 16.4% in this study. The IDF estimates of the total diabetes prevalence were considerably lower at 16.7% in 2011 and 20.8% in 2030, compared with 29.2% in 2011 and 44.1% in 2022 in this study. Conclusion In contrast to other modelling studies, both the Saudi IMPACT Diabetes Forecast Model and the GBD model directly incorporated the trends in obesity prevalence and/or body mass index (BMI) to inform T2DM prevalence estimates. It appears that such a direct incorporation of obesity trends in modelling studies results in higher estimates of the future prevalence of T2DM, at least in countries where obesity has been rapidly increasing. PMID:24447810

  7. High prevalence of abdominal obesity increases the risk of the metabolic syndrome in Nigerian type 2 diabetes patients: using the International Diabetes Federation worldwide definition.

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    Ezenwaka, Chidum E; Okoye, Osita; Esonwune, Chibuike; Onuoha, Philip; Dioka, Chudi; Osuji, Charles; Oguejiofor, Celestine; Meludu, Samuel

    2014-06-01

    Some Nigerian studies have reported cases of the metabolic syndrome in the population. This study aims to assess the prevalence of the components of the metabolic syndrome in type 2 diabetes mellitus (T2DM) patients using the International Diabetes Federation (IDF) worldwide definition. Eighty-nine T2DM patients were studied after an overnight fast. The patients' blood pressure, anthropometric indices, and biochemical parameters were measured. The components of the metabolic syndrome-raised blood pressure, waist circumference, triglycerides (TGs), and reduced high-density lipoprotein cholesterol (HDL-C)-were calculated using the IDF definition for the European ethnic group. About 25% of the patients had raised blood pressure (>130/85 mmHg), with the male patients having higher prevalence of raised systolic blood pressure (SBP>130 mmHg) than the female patients (73.3 vs. 52.3%, P0.05), abdominal obesity predominates significantly in female patients (97.7 vs. 68.9%, Prisk of cardiovascular disease (CVD). We recommend that diabetes education emphasizing the risk of CVD in patients with increased abdominal fat should be intensified in the developing countries.

  8. Prevalence of the metabolic syndrome among North Indian adolescents using Adult Treatment Panel III and pediatric International Diabetic Federation definitions

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    Riyaz Ahmad Bhat

    2015-01-01

    Full Text Available Background and Objective: Childhood obesity is an important risk factor for the development of metabolic syndrome (MS in children and adolescent. Because of high prevalence of insulin resistance and MS in Indian adult population, studies are needed to identify the prevalence of these metabolic abnormalities in the adolescent population. The objective of this study was to estimate the prevalence of MS using pediatric International Diabetic Federation (IDF definition and compare it with estimates of Adult Treatment Panel III (ATP III definition among adolescents in Northern India. Materials and Methods: At a total of 899 adolescents attending school (aged 10-18 years participated in this population-based prospective study. All the clinical and biochemical assessment were done after proper consent. The MS was determined by the National Cholesterol Education Program ATP III definition modified for age and pediatric IDF definition. Results: The prevalence of MS was 3.5% according to ATP III criteria and 1.5% based on IDF criteria. No significant gender difference was observed in the distribution of MS. Hypertriglyceridemia was the most common and abdominal obesity the least common constituent of MS. Conclusion: This study provides the first estimates of MS using pediatric IDF definition in the adolescent population from Northern India.

  9. Prevalence of metabolic syndrome defined by the International Diabetes Federation and National Cholesterol Education Program criteria among Thai adults.

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    Aekplakorn, Wichai; Chongsuvivatwong, Virasakdi; Tatsanavivat, Pyatat; Suriyawongpaisal, Paibul

    2011-09-01

    This study determines the prevalence of metabolic syndrome (MetS) according to the International Diabetes Federation (IDF) and National Cholesterol Education Program III (NCEP) criteria in Thai adults. Data from a national representative sample, InterASIA study, including a total of 5305 Thai adults 35 years and older were analyzed. Overall, the age-standardized prevalence of MetS by IDF and NCEP criteria were 24.0% (men 16.4%, women 31.6%) and 32.6% (men 28.7%, women 36.4%), respectively. The difference in prevalence of MetS between genders was much greater for the IDF compared with the NCEP definition. The age-standardized prevalence rates distributed by geographic region were relatively uniform with a lowest prevalence in the northeast. Among all possible sets of components for MetS, the most common combinations were a set of low high-density lipoprotein cholesterol, high triglyceride, and hyperglycemia in men (3.9%) and a set of abdominal obesity, low high-density lipoprotein cholesterol, and high triglycerides in women (6.7%). MetS is common in Thai adults and NCEP definition captures more cases of MetS compared with the IDF definition. Implementation of programs to prevent obesity and metabolic factors along with future periodic survey to monitor the problem is crucial.

  10. Prevalence of metabolic syndrome according to Adult Treatment Panel III and International Diabetes Federation criteria: a population-based study.

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    Bener, Abdulbari; Zirie, Mahmoud; Musallam, Manal; Khader, Yousef S; Al-Hamaq, Abdulla O A A

    2009-06-01

    The objective of the study was to examine the prevalence of metabolic syndrome among adult Qatari population according to the revised criteria of the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) and the International Diabetes Federation (IDF), assess which component contributed to the increased risk of the metabolic syndrome, and identify the characteristics of the subjects with metabolic syndrome. This was a cross-sectional study. The survey was carried out in urban and semiurban primary health-care centers. The survey was conducted from January, 2007, to July, 2008, among Qatari nationals above 20 years of age. Of the 1496 subjects who were approached to participate in the study, 1204 (80.5%) gave their consent. Face-to-face interviews were conducted using a structured questionnaire followed by laboratory tests. Metabolic syndrome was defined using the NCEP ATP III as well as IDF criteria. The overall prevalence of metabolic syndrome in studied subjects was 26.5% and 33.7% according to ATP III and IDF criteria (P education and physical activity. Also, the prevalence of metabolic syndrome was more common in women. Among the components of metabolic syndrome, central obesity was significantly higher in the studied subjects. The IDF definition of metabolic syndrome gave a higher prevalence in all age groups. The overall prevalence of metabolic syndrome and its components according to IDF criteria was higher in the studied subjects than the estimates given by the ATP III. Multivariate logistics regression analysis (ATP III and IDF) showed that age and BMI were significant contributors for metabolic syndrome. Both definitions strongly supported age and obesity as associated factors for metabolic syndrome. The current study found a high prevalence of metabolic syndrome among Qataris. There was a steady increase in the prevalence of metabolic syndrome through the decades, independent of the definition. Age and BMI were important

  11. Risk factors associated with metabolic syndrome in type 2 diabetes mellitus patients according to World Health Organization, Third Report National Cholesterol Education Program, and International Diabetes Federation definitions.

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    Rodríguez, Angel; Delgado-Cohen, Helena; Reviriego, Jesús; Serrano-Ríos, Manuel

    2010-12-16

    The availability of several definitions of the metabolic syndrome has created potential confusion concerning its prognostic utility. At present, little data exist about the risk factors associated with metabolic syndrome in diabetic patients. To identify risk factors associated with metabolic syndrome in patients with type 2 diabetes mellitus according to three diagnostic criteria: World Health Organization (WHO), Third Report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults - Adult Treatment Panel III (NCEP-ATP III), and International Diabetes Federation (IDF). A logistic regression model was used to identify demographic, clinical, and lifestyle variables related with metabolic syndrome (N = 1259). Hypertension, dyslipidemia, and glycosylated hemoglobin (HbA(1c)) ≥7% were associated with increased risk of WHO-defined metabolic syndrome (odds ratio [OR], 2.33; 95% confidence interval [CI]: 1.60-3.40; OR, 1.79 95% CI: 1.25-2.55; and OR, 1.58; 95% CI: 1.12-2.22, respectively). The risk of presenting metabolic syndrome according to NCEP-ATP III criteria was increased in female patients (OR, 2.02; 95% CI: 1.37-2.97), elevated fasting glucose levels (OR, 5.99; 95% CI: 3.56-10.07), dyslipidemia (OR, 2.28; 95% CI: 1.57-3.32), hypertension (OR, 2.36; 95% CI: 1.59-3.53), and endocrine disorders (OR, 1.64; 95% CI: 1.06-2.57). For the IDF criteria, female patients and patients with left ventricular hypertrophy or insulin treatment were at higher risk of metabolic syndrome (OR, 4.00; 95% CI: 2.35-6.80; OR, 2.72 95% CI: 1.22-6.04; and OR, 1.96 95% CI: 1.24-3.11, respectively). The risk factors for metabolic syndrome in type 2 diabetes mellitus patients are highly dependent on the criteria used to define the syndrome, supporting the need for a single clinically useful and epidemiologically useful definition.

  12. An evaluation of the International Diabetes Federation definition of metabolic syndrome in Chinese patients older than 30 years and diagnosed with type 2 diabetes mellitus.

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    Lu, Bin; Yang, Yehong; Song, Xiaoyan; Dong, Xuehong; Zhang, Zhaoyun; Zhou, Linuo; Li, Yiming; Zhao, Naiqing; Zhu, XiXing; Hu, Renming

    2006-08-01

    The objective of the study was to determine the most accurate metabolic syndrome (MS) definition among the definitions proposed by the International Diabetes Federation (IDF), the Third Report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III [ATPIII]), and the World Health Organization (WHO) and to evaluate the cutoff point of waist circumference using the IDF definition for optimally defining MS in the Chinese population. One thousand thirty-nine Chinese patients older than 30 years and diagnosed with type 2 diabetes mellitus were investigated by randomized cluster sampling in the Shanghai downtown, and 1008 patients were analyzed in this study. Body mass measurements, resting blood pressure, fasting blood measures, and carotid atherosclerotic measurements including common carotid artery intima-media thickness (IMT) and carotid plaque were investigated. The IDF definition was compared with the other 2 definitions, and the carotid atherosclerosis was evaluated among the patients according to these definitions. (1) The MS prevalence was 50.0%, 55.7%, and 70.0% under the IDF, ATPIII, and WHO definitions, respectively. (2) The percentage of all the participants categorized as either having or not having the MS was 69.9% (under the IDF and ATPIII definitions) and 70.2% (under the IDF and WHO definitions). (3) Common carotid artery IMT of patients with MS determined by the IDF definition was thicker than those determined by the WHO and ATPIII definitions, and the percentage of carotid plaque of patients with MS determined by the IDF definition was greater than those determined by the WHO and ATPIII definitions. (4) When the cutoff point of waist circumference in men determined by the IDF definition was modified from 90 to 85 cm, common carotid artery IMT of the emerging male patients with MS was thicker than that of the male patients with MS determined by the

  13. Prevalence of the metabolic syndrome among Korean adults using the new International Diabetes Federation definition and the new abdominal obesity criteria for the Korean people.

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    Kim, Hee Man; Kim, Dae Jung; Jung, In Hyun; Park, Chanwang; Park, Jong

    2007-07-01

    This study was performed to compare the prevalence of the metabolic syndrome according to the International Diabetes Federation (IDF) and National Cholesterol Education Program (NCEP) definitions, and abdominal obesity criteria of WHO and the Korean Society for the Study of Obesity (KSSO) in Korean adults. A total of 4452 adults aged > or =20 years from the Korean National Health and Nutrition Examination Survey 2001 were analyzed. The prevalence of the metabolic syndrome estimated by NCEP definition with WHO criteria, NCEP with KSSO, IDF with WHO, and IDF with KSSO were 26.7%, 23.7%, 23.8% and 17.5%, respectively. The agreement percent among the four definitions ranged from 88.7% to 100% in men, and from 85.6% to 94.9% in women. The NCEP-defined metabolic syndrome was more strongly associated with hypertension and diabetes than the IDF-defined metabolic syndrome (age-adjusted odds ratio: 5.1 versus 3.6 for hypertension and 6.4 versus 3.2 for diabetes in men, respectively; 5.4 versus 3.4-4.3 for hypertension and 11.1 versus 3.8-4.2 for diabetes in women, respectively). Both definitions of the metabolic syndrome were associated with coronary heart disease or stroke only in women. Prospective studies are warranted to evaluate the predictive ability of the new definition of the metabolic syndrome and the new criteria of abdominal obesity for cardiovascular morbidity and mortality in Korean adults.

  14. Metabolic syndrome in children: comparison of the International Diabetes Federation 2007 consensus with an adapted National Cholesterol Education Program definition in 300 overweight and obese French children.

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    Druet, Céline; Ong, Ken; Levy Marchal, Claire

    2010-01-01

    Former definitions of metabolic syndrome (MS) in children have been adapted from adult MS definitions using age-related thresholds for each biochemical component, whereas the International Diabetes Federation (IDF) definition is based on absolute values. We compared the IDF childhood MS definition (IDF-MS) to the adapted National Cholesterol Education Program (adapted-NCEP) definition in overweight children. 300 overweight and obese children were included with a median age of 11 years and BMI SDS of +4.7. Below 10 years of age, the frequency of MS according to the adapted-NCEP-MS definition was 18.6%, and 86.1% had abdominal obesity. In children aged 10 to definition and appears to identify a group of children with higher fasting insulin than the adapted-MS definition which uses age-related thresholds (90th percentile). Copyright 2010 S. Karger AG, Basel.

  15. Prevalence of metabolic syndrome in urban Pakistan (Karachi): comparison of newly proposed International Diabetes Federation and modified Adult Treatment Panel III criteria.

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    Hydrie, M Zafar Iqbal; Shera, A Samad; Fawwad, Asher; Basit, Abdul; Hussain, Akhtar

    2009-04-01

    The clustering of central obesity, dyslipidemia, hypertension, and hyperglycemia known as metabolic syndrome has been associated with a two- to three-fold increase in type 2 diabetes (T2DM) and cardiovascular disease (CVD). It is recognized that the features of the metabolic syndrome can be present 10 years preceding T2DM and CVD. The objective of our study was to determine the prevalence of metabolic syndrome in adults aged 25 years and older from an urban population of Karachi, Pakistan, according to the International Diabetes Federation (IDF) definition and modified Adult Treatment Panel III (ATP III) criteria. This study involved a survey conducted from July, 2004, to December, 2004, by generating a computerized random sample of households in Lyari Town using a geographical imaging system (GIS). Out of the 85,520 households, 532 households were randomly selected and 867 adults > or =25 years old consented to take part in the survey; 363 of these subjects gave blood samples. The prevalence of diabetes was 9.4%, whereas 5.6% had impaired fasting glucose (abnormal glucose tolerance 15%). The prevalence of metabolic syndrome according to the IDF definition and modified ATP III criteria was 34.8% and 49%, respectively. Inclusion of modified waist circumference and specific body mass index (BMI) cut offs for Asians may help predict metabolic syndrome at an early stage. High prevalence of metabolic syndrome was identified irrespective of the definition applied in this population. This may call for immediate action to halt the accelerating risk of diabetes and CVD that would lead to a possible unparalleled rise in the cost of health care and human suffering.

  16. Do albuminuria and hs-CRP add to the International Diabetes Federation definition of the metabolic syndrome in predicting outcome?

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    van der Velde, Marije; Bello, Aminu K.; Brantsma, Auke H.; El Nahas, Meguid; Bakker, Stephan J. L.; de Jong, Paul E.; Gansevoort, Ronald T.

    Background. To investigate the added value of elevated urinary albumin excretion (UAE) and high high-sensitive C-reactive protein (hs-CRP) in predicting new-onset type 2 diabetes mellitus (T2DM), cardiovascular disease (CVD) and chronic kidney disease (CKD) in addition to the present metabolic

  17. Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity.

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    Alberti, K G M M; Eckel, Robert H; Grundy, Scott M; Zimmet, Paul Z; Cleeman, James I; Donato, Karen A; Fruchart, Jean-Charles; James, W Philip T; Loria, Catherine M; Smith, Sidney C

    2009-10-20

    A cluster of risk factors for cardiovascular disease and type 2 diabetes mellitus, which occur together more often than by chance alone, have become known as the metabolic syndrome. The risk factors include raised blood pressure, dyslipidemia (raised triglycerides and lowered high-density lipoprotein cholesterol), raised fasting glucose, and central obesity. Various diagnostic criteria have been proposed by different organizations over the past decade. Most recently, these have come from the International Diabetes Federation and the American Heart Association/National Heart, Lung, and Blood Institute. The main difference concerns the measure for central obesity, with this being an obligatory component in the International Diabetes Federation definition, lower than in the American Heart Association/National Heart, Lung, and Blood Institute criteria, and ethnic specific. The present article represents the outcome of a meeting between several major organizations in an attempt to unify criteria. It was agreed that there should not be an obligatory component, but that waist measurement would continue to be a useful preliminary screening tool. Three abnormal findings out of 5 would qualify a person for the metabolic syndrome. A single set of cut points would be used for all components except waist circumference, for which further work is required. In the interim, national or regional cut points for waist circumference can be used.

  18. Differences in traditional and emerging cardiovascular risk factors of subjects discordantly classified by metabolic syndrome definitions of the International Diabetes Federation and the National Cholesterol Education Program.

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    Boronat, M; Saavedra, P; Varillas, V F; Wagner, A M; López-Plasencia, Y; Alberiche, M P; Nóvoa, F J

    2009-07-01

    Several working definitions of metabolic syndrome have been proposed for clinical use. However, individuals can be discordantly classified as having or not having metabolic syndrome depending on the choice of one or another definition. This study compared the cardiovascular risk profile of subjects concordantly and discordantly diagnosed by the criteria of the National Cholesterol Education Program (NCEP) and the criteria of the International Diabetes Federation (IDF). Nine hundred and twenty-nine non-diabetic adult subjects belonging to a cross-sectional population-based study in Gran Canaria island (Spain) were assessed. Participants completed a questionnaire and underwent physical examination, fasting blood analyses, and a standardized oral glucose tolerance test. Two hundred and four subjects (22%) had metabolic syndrome according to both definitions, 31 (3.3%) only by the IDF criteria, and 5 (0.5%) only by the NCEP criteria. Participants fulfilling both proposals showed more adverse age and sex-adjusted measures of BMI, waist, HDL cholesterol, triglycerides, post-load glucose, HOMA-IR and plasminogen inhibitor activator-1 (PAI-1) than individuals exclusively satisfying the IDF criteria. Moreover, in contrast to subjects meeting both criteria, those that fulfilled only the IDF criteria had levels of BMI, waist, total and HDL cholesterol, post-load glucose, glycated HbA1c, C-reactive protein, PAI-1 and fibrinogen not significantly different from those observed in subjects without metabolic syndrome. The IDF definition identifies a surplus of individuals whose cardiovascular risk profile, particularly regarding to some non-traditional cardiovascular risk factors, is less adverse than that observed in subjects also diagnosed by the NCEP definition.

  19. [Concordance between three definitions for metabolic syndrome (Hypertriglyceridemic waist, National Cholesterol Education Program, International Diabetes Federation), and prevalence of the syndrome in a French population].

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    Nawabzad, Raphaël; Champin, Bernard

    2010-12-20

    The metabolic syndrome is associated with an increased risk of diabetes and cardiovascular disease. However, only the Hypertriglyceridemic waist (HTGW) criterions have been chosen for their ability to identify a group of patients with a higher cardiovascular risk independently of the traditional risk factors. The aim of this study was to examinate the real concordance of the metabolic syndrome according to the HTGW definition, National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) definition and the International Diabetes Federation (IDF) definition. We also evaluated the prevalence of the metabolic syndrome in a French population. The study was conducted on a sample of 232 patients, of both sexes, aged from 30 to 65 years old, recruited in general practice. Patients had a medical examination, and biological analyses were performed to assess their metabolic status. Kappa concordance coefficient was 0.46 between HTGW and NCEP ATP III; it was 0.43 between HTGW and IDF, and 0.59 between NCEP ATP III and IDF. The prevalence of the metabolic syndrome according to the HTGW in the sample was 16.8%, 18.3% in men and 15.4% in women. According to NCEP ATP IlI prevalence were respectively 20.3%, 20.9%, and 19.7%. According to IDF they were respectively 28.4%, 33%, and 23.9%. We recommend paying the same attention to the metabolic syndrome than to the traditional cardiovascular risk factors, and we recommend the use of the HTGW definition as diagnostic tool.

  20. Comparison of the prevalence of metabolic syndrome and its association with diabetes and cardiovascular disease in the rural population of Bangladesh using the modified National Cholesterol Education Program Expert Panel Adult Treatment Panel III and International Diabetes Federation definitions

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    Bhowmik, Bishwajit; Afsana, Faria; Siddiquee, Tasnima; Munir, Sanjida B; Sheikh, Fareeha; Wright, Erica; Bhuiyan, Farjana R; Ashrafuzzaman, Sheikh Mohammad; Mahtab, Hajera; Azad Khan, Abul Kalam; Hussain, Akhtar

    2015-01-01

    Aims/Introduction To compare the prevalence of metabolic syndrome (MS) using the modified National Cholesterol Education Program Adult Treatment Plan III (NCEP) and the International Diabetes Federation (IDF) definitions and, using both definitions, determine and compare the association of MS, prediabetes, type 2 diabetes, hypertension (HTN) and cardiovascular disease risk (CVD). Materials and Methods A total of 2,293 randomly selected participants (aged ≥20 years) in a rural community in Bangladesh were investigated in a population-based cross-sectional study. Sociodemographic and anthropometric characteristics, blood pressure, blood glucose, and lipid profiles were studied. Age-adjusted data for MS and cardiometabolic risk factors were assessed, and their relationships were examined. Results The age-adjusted prevalence of MS was 30.7% (males 30.5%; females 30.5%) using the NCEP definition, and 24.5% (males 19.2%, females 27.5%) using the IDF definition. The prevalence of MS using the NCEP definition was also higher in study participants with prediabetes, type 2 diabetes, HTN and CVD risk. The agreement rate between both definitions was 92% (k = 0.80). The NCEP definition had a stronger association with type 2 diabetes and HTN (odds ratio 12.4 vs 5.2; odds ratio 7.0 vs 4.7, respectively) than the IDF definition. However, the odds ratios for prediabetes and CVD risk were not significantly different. Conclusions The prevalence of MS was higher using the NCEP definition, and was more strongly associated with prediabetes, type 2 diabetes, HTN and CVD in this Bangladeshi population. PMID:25969712

  1. Comparison of the prevalence of metabolic syndrome and its association with diabetes and cardiovascular disease in the rural population of Bangladesh using the modified National Cholesterol Education Program Expert Panel Adult Treatment Panel III and International Diabetes Federation definitions.

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    Bhowmik, Bishwajit; Afsana, Faria; Siddiquee, Tasnima; Munir, Sanjida B; Sheikh, Fareeha; Wright, Erica; Bhuiyan, Farjana R; Ashrafuzzaman, Sheikh Mohammad; Mahtab, Hajera; Azad Khan, Abul Kalam; Hussain, Akhtar

    2015-05-01

    To compare the prevalence of metabolic syndrome (MS) using the modified National Cholesterol Education Program Adult Treatment Plan III (NCEP) and the International Diabetes Federation (IDF) definitions and, using both definitions, determine and compare the association of MS, prediabetes, type 2 diabetes, hypertension (HTN) and cardiovascular disease risk (CVD). A total of 2,293 randomly selected participants (aged ≥20 years) in a rural community in Bangladesh were investigated in a population-based cross-sectional study. Sociodemographic and anthropometric characteristics, blood pressure, blood glucose, and lipid profiles were studied. Age-adjusted data for MS and cardiometabolic risk factors were assessed, and their relationships were examined. The age-adjusted prevalence of MS was 30.7% (males 30.5%; females 30.5%) using the NCEP definition, and 24.5% (males 19.2%, females 27.5%) using the IDF definition. The prevalence of MS using the NCEP definition was also higher in study participants with prediabetes, type 2 diabetes, HTN and CVD risk. The agreement rate between both definitions was 92% (k = 0.80). The NCEP definition had a stronger association with type 2 diabetes and HTN (odds ratio 12.4 vs 5.2; odds ratio 7.0 vs 4.7, respectively) than the IDF definition. However, the odds ratios for prediabetes and CVD risk were not significantly different. The prevalence of MS was higher using the NCEP definition, and was more strongly associated with prediabetes, type 2 diabetes, HTN and CVD in this Bangladeshi population.

  2. Geographic variations of the International Diabetes Federation and the National Cholesterol Education Program-Adult Treatment Panel III definitions of the metabolic syndrome in nondiabetic subjects.

    Science.gov (United States)

    Lorenzo, Carlos; Serrano-Ríos, Manuel; Martínez-Larrad, María T; González-Sánchez, José L; Seclén, Segundo; Villena, Arturo; Gonzalez-Villalpando, Clicerio; Williams, Ken; Haffner, Steven M

    2006-03-01

    We have carried out international comparisons of the metabolic syndrome using the International Diabetes Federation (IDF) and National Cholesterol Education Program-Adult Treatment Panel III (ATP III) definitions. This analysis could help to discern the applicability of these definitions across populations. Nondiabetic subjects aged 35-64 years were eligible for analysis in population-based studies from San Antonio (Mexican Americans and non-Hispanic whites, n = 2,473), Mexico City (n = 1,990), Spain (n = 2,540), and Peru (n = 346). Kappa statistics examined the agreement between metabolic syndrome definitions. Because of the lower cutoff points for elevated waist circumference, the IDF definition of the metabolic syndrome generated greater prevalence estimates than the ATP III definition. Prevalence difference between definitions was more significant in Mexican-origin and Peruvian men than in Europid men from San Antonio and Spain because the IDF definition required ethnic group-specific cutoff points for elevated waist circumference. ATP III and IDF definitions disagreed in the classification of 13-29% of men and 3-7% of women. In men, agreement between these definitions was 0.54 in Peru, 0.43 in Mexico City, 0.62 in San Antonio Mexican Americans, 0.69 in San Antonio non-Hispanic whites, and 0.64 in Spain. In women, agreement between definitions was 0.87, 0.89, 0.86, 0.87, and 0.93, respectively. The IDF definition of the metabolic syndrome generates greater prevalence estimates than the ATP III definition. Agreement between ATP III and IDF definitions was lower for men than for women in all populations and was relatively poor in men from Mexico City.

  3. National Cholesterol Education Program Adult Treatment Panel III Versus International Diabetic Federation Definition of Metabolic Syndrome, Which One is Associated with Diabetes Mellitus and Coronary Artery Disease?

    Science.gov (United States)

    Rezaianzadeh, Abbas; Namayandeh, Seyedeh-Mahdieh; Sadr, Seyed-Mahmood

    2012-08-01

    A cluster of risk factors for cardiovascular diseases and type 2 diabetes mellitus, which occur together more often than by chance alone, have been known as the metabolic syndrome. Various definitions have been proposed by different organizations over the past decade. This study was designed to evaluate a new definition of the metabolic syndrome for the prediction of diabetes mellitus among the Iranian population. This study was carried out in an urban population, aged 20 to 74 years, from Yazd, a city in the center of Iran. The study is a part of the phase I of Yazd Healthy Heart Program, that is, a community-based intervention study for the prevention of cardiovascular disease. The significance level has been defined as Pdefinitions of NCEP and IDF criteria, and also, the most important relevant factors of stable angina were: Increased age, male sex, and metabolic syndrome by only IDF definitions, but the NCEP definition of the metabolic syndrome cannot predict diabetes mellitus independent of age and sex. This study showed that increased age and metabolic syndrome are the most important relevant factors for diabetes mellitus, especially by using the IDF criteria for definition of the metabolic syndrome.

  4. Does the new International Diabetes Federation definition of metabolic syndrome improve prediction of coronary artery disease and carotid intima-media thickening?

    Science.gov (United States)

    Timóteo, Ana; Santos, Rui; Lima, Sandra; Mamede, Andreia; Fernandes, Rita; Ferreira, Rui

    2009-02-01

    Metabolic syndrome (MS) is associated with increased incidence of diabetes and atherosclerotic complications. The new definition of the International Diabetes Federation (IDF) increases the population with this entity, compared to the NCEP ATP III definition. To study the prevalence of coronary artery disease (CAD) and carotid intima-media thickness (IMT) in patients with and without MS, according to the NCEP ATP III and IDF definitions, and the predictive ability of carotid IMT for CAD. We studied 270 consecutive patients admitted for elective coronary angiography due to suspicion of CAD. All patients underwent ultrasound study of the carotid arteries to measure IMT (the highest value between the right and left common carotid arteries was used in the analysis). Coronary stenosis of > or =70% (or 50% for the left main coronary artery) was considered significant. By the ATP III definition, 14% of the patients had MS, and these patients had a higher prevalence of CAD (87% vs. 63%, p = 0.004), but no significant difference was found for carotid IMT (1.03 +/- 0.36 mm vs. 0.95 +/- 0.35 mm, p=NS). With the IDF definition, 61% of the patients had MS; this group was slightly older and included more women. There were no differences in terms of CAD (68% vs. 63%) or carotid IMT (0.97 +/- 0.34 vs. 0.96 +/- 0.39 mm). On multivariate analysis, the ATP III definition of MS predicts CAD (OR 4.76, 95% CI 1.71-13.25, p = 0.003), but the IDF definition does not (OR 1.29, 95% CI 0.74-2.27, p = 0.37). On ROC curve analysis, an IMT of > or = 0.95 mm predicts CAD (AUC 0.66, p definition increases the population with MS, decreasing the capacity to predict the presence of CAD. In our population, neither the ATP III nor the IDF definition showed differences in terms of carotid IMT. Carotid IMT can predict CAD, but with only modest sensitivity.

  5. Prevalence of Metabolic Syndrome among Malaysians using the International Diabetes Federation, National Cholesterol Education Program and Modified World Health Organization Definitions.

    Science.gov (United States)

    Bee, Ying Tan; Haresh, Kumar Kantilal; Rajibans, Singh

    2008-03-01

    The World Health Organization (WHO), National Cholesterol Education Program Adults Treatment Panel III (NCEP ATP III) and International Diabetes Federation (IDF) have proposed different criteria to diagnose metabolic syndrome (MetS). However, there is no single definition to accurately diagnose MetS. The objective of this study is to estimate the prevalence of MetS using WHO, NCEP ATP III and IDF in the Malaysian community, and to determine the concordance between these definitions for MetS. 109 men and women aged > 30 years participated in the study, and the prevalence of MetS was determined according to the three definitions. Weight, height, body mass index (BMI), waist-hip circumference, blood pressure, blood lipid profile and plasma fasting glucose were measured. In order to determine the concordance between IDF and the other two definitions, the kappa index (κ-test) was used. The prevalence of MetS (95% confidence interval) was 22.9% (22.8-23.1) by IDF definition, 16.5% (16.3-16.9) by NCEP ATP III definition and 6.4% (6.2-6.6) by modified WHO definition. The sensitivity and specificity of IDF against NCEP ATP III were 88.9% and 90.1% respectively, IDF against WHO definition were 85.7% and 81.4%. The κ statistics for the agreement of the IDF definition was 68.3 ± 0.1 with the NCEP ATP III, and 30.5 ± 0.1 with the modified WHO definition. The prevalence of the MetS among respondents using the IDF definition was highest, followed by NCEP ATP III, and finally modified WHO definition. There was a good concordance between the IDF and NCEP ATP III definitions, and a low concordance between IDF and modified WHO definitions.

  6. Prevalence of metabolic syndrome among staff in a Malaysian public university based on Harmonised, International Diabetes Federation and National Cholesterol Education Program Definitions.

    Science.gov (United States)

    Heng, K S; Hejar, A R; Rushdan, A Z; Loh, S P

    2013-04-01

    Metabolic syndrome (MetSyn) as defined by the latest Harmonised definition and the agreement between the Harmonised definition and other definitions is poorly studied among Malaysians. This study was conducted to determine and compare the prevalence of MetSyn according to the Harmonised, International Diabetes Federation (IDF) and National Cholesterol Education Program (NCEP ATPIII) definitions among Malay staff of Universiti Putra Malaysia (UPM). Subjects aged between 20 to 65 years were recruited by convenient sampling. Waist circumference, blood pressure, lipid profiles and fasting plasma glucose levels were assessed. The agreement between the Harmonised and other definitions was determined by Kappa statistics. A total of 227 subjects with a mean +/- SD age of 37.9 +/- 9.6 years participated in the study. The overall prevalence of MetSyn was 38.3%, 38.8% and 33.5% according to Harmonised, IDF and NCEP ATP III definitions, respectively. Generally, men had higher prevalence of MetSyn than women. The prevalence increased with age in both genders with a more progressive trend in women. Men in the age group of 20-39 years had a high prevalence of metabolic syndrome. A strong agreement was found between the Harmonised and the IDF definitions (Kappa index = 0.991), and between the Harmonised and the NCEP ATP III definitions (Kappa index = 0.857). Regardless of definitions used, the prevalence of metabolic syndrome in the study, especially in young men, was high and warrants further investigation. The Harmonised definition is suitable for diagnosing metabolic syndrome in any population with similar sociodemographic characteristics.

  7. The New Unified International Diabetes Federation/American Heart Association/National Heart, Lung, and Blood Institute Metabolic Syndrome definition: does it correlate better with C-reactive protein in Chinese patients diagnosed with type 2 diabetes?

    Science.gov (United States)

    Lu, B; Zhang, S; Wen, J; Yang, Y; Yang, Z; Zhang, Z; Wang, X; Hu, R

    2010-01-01

    This study evaluated the association between high-sensitivity C-reactive protein (hsCRP) and metabolic syndrome, defined by the definition proposed by the International Diabetes Federation (IDF), American Heart Association (AHA) and National Heart, Lung, and Blood Institute (NHLBI) versus the older IDF definition, in 506 Chinese patients with type 2 diabetes. Anthropometric and biochemical parameters were compared and analysed using multivariate linear regression models. Serum hsCRP was higher in patients with metabolic syndrome compared with those without metabolic syndrome for both definitions and increased as the number of components of metabolic syndrome increased (after adjusting for age, gender and smoking). Patients with metabolic syndrome according to the IDF/AHA/NHLBI but not the IDF definition had significantly higher hsCRP levels than those not meeting either definition and similar hsCRP levels to those meeting both definitions. Serum hsCRP levels were significantly associated with metabolic syndrome according to the IDF definition after adjusting for age, gender and smoking. Adding metabolic syndrome status according to the IDF/AHA/NHLBI definition significantly increased the fit of the multivariate linear regression model. The new IDF/AHA/NHLBI definition of metabolic syndrome may have a stronger relationship with serum hsCRP than the IDF definition.

  8. The usefulness of the International Diabetes Federation and the National Cholesterol Education Program's Adult Treatment Panel III definitions of the metabolic syndrome in predicting coronary heart disease in subjects with type 2 diabetes.

    Science.gov (United States)

    Tong, Peter C; Kong, Alice P; So, Wing-Yee; Yang, Xilin; Ho, Chung-Shun; Ma, Ronald C; Ozaki, Risa; Chow, Chun-Chung; Lam, Christopher W; Chan, Juliana C N; Cockram, Clive S

    2007-05-01

    The purpose of this study was to compare the predictive value for coronary heart disease (CHD) of the International Diabetes Federation (IDF) definition (with Asian criteria for central obesity) of the metabolic syndrome with existing criteria of the National Cholesterol Education Program (NCEP) Adult Treatment Panel III (ATP III) in Chinese subjects with type 2 diabetes. Subjects with type 2 diabetes and without macrovascular diseases or end-stage renal disease were categorized by the criteria of the IDF and the NCEP ATP III. CHD was defined as myocardial infarction, ischemic heart disease, coronary revascularization, heart failure, and death related to CHD. Of 4,350 patients (aged 54.4 +/- 13.4 years; median follow-up period 7.1 [interquartile range 5.2-8.5] years), 65.9% had metabolic syndrome according to either IDF or NCEP ATP III criteria. The NCEP ATP III definition identified metabolic syndrome in 786 subjects (18.1%) who did not fulfill the criteria of the IDF. HDL cholesterol and systolic blood pressure were predictors of CHD after adjustment for other confounding factors. Compared with subjects without metabolic syndrome, the IDF criteria failed to predict CHD (hazard ratio 1.13 [95% CI 0.86-1.48], P = 0.374). In contrast, the NCEP ATP III definition (2.51 [1.80-3.50], P definition of the metabolic syndrome failed to identify a subgroup of patients who had the highest risk for CHD. Practitioners must recognize the appropriate setting for its application.

  9. Prevalence and cardiovascular disease risk of the metabolic syndrome using National Cholesterol Education Program and International Diabetes Federation definitions in the Korean population.

    Science.gov (United States)

    Choi, Kyung Mook; Kim, Seon Mee; Kim, Yeong-Eun; Choi, Dong Seop; Baik, Sei Hyun; Lee, Juneyoung

    2007-04-01

    To compare the prevalence of the metabolic syndrome using the National Cholesterol Education Program (NCEP) and the International Diabetes Federation (IDF) definitions and to contrast the association between the prevalence of cardiovascular disease and the metabolic syndrome using both definitions in the Korean population, we used data from the 2001 Korean Nation Health and Nutrition Survey, which is a nationally representative survey of the noninstitutionalized civilian population. The age-adjusted prevalence of the metabolic syndrome was 18.8%+/-0.5% (men, 17.8%+/-0.8%; women, 20.5%+/-0.7%) using the NCEP definition and 19.5%+/-0.5% (men 15.0%+/-0.8%, women 23.9%+/-0.7%) using the IDF definition among participants 20 years or older. The agreement rate, which is the percentage of participants who were classified as either having or not having the metabolic syndrome by both definitions of the metabolic syndrome, was 84.6%+/-0.5% (kappa=0.54). The prevalence of the metabolic syndrome using the NCEP definition was higher in participants with lower body mass index, whereas the prevalence using the IDF definition was higher in subjects with higher body mass index. The odds ratio (OR) for coronary artery disease was 3.5 (95% confidence interval [CI], 2.0-6.1) for participants with the metabolic syndrome defined by the NCEP definition, whereas it was 2.8 (95% CI, 1.6-5.0) for those with the metabolic syndrome defined by the IDF definition. Similarly, the OR for stroke was higher using the NCEP definition (OR, 3.0; 95% CI, 1.7-5.2) compared with that of the IDF definition (OR, 2.3; 95% CI, 1.3-4.0). However, the CIs by both definitions overlapped considerably. In conclusion, the prevalence of the metabolic syndrome using the IDF definition was higher than that using the NCEP definition, whereas the NCEP definition was more closely associated with cardiovascular disease in the Korean population.

  10. NASA and the Federal Management Intern Program.

    Science.gov (United States)

    Pound, Jack K.; Slack, Vivian M.

    A review of NASA Federal Management Intern (MI) programs indicates potential for identification, attraction, and early development of successful administrative management employees, but suggests that successful development of managers is a function of the long-term care with which an agency pursues MI programs. A recent study of separations in…

  11. The reliability of the National Cholesterol Education Program's Adult Treatment Panel III (NCEP/ATP III) and the International Diabetes Federation (IDF) definitions in diagnosing metabolic syndrome (MetS) among Gaza Strip Palestinians.

    Science.gov (United States)

    Sirdah, Mahmoud M; Abu Ghali, Asmaa S; Al Laham, Nahed A

    2012-01-01

    Metabolic syndrome (MetS) which is a multifaceted syndrome, has been demonstrated as a common precursor for developing cardiovascular diseases and/or type 2 diabetes mellitus. Different diagnostic definitions for MetS have been proposed and recommended. We set up to evaluate the reliabilities of the National Cholesterol Education Program's Adult Treatment Panel III (NCEP/ATP III) and the International Diabetes Federation (IDF) definitions in diagnosing MetS among Gaza Strip Palestinians. This cross sectional study involved a randomly selected two hundred and thirty apparently healthy adults from the Gaza Strip. Anthropometric measurements, blood pressure, fasting plasma glucose, lipid profile, and questionnaire interviews were performed. The overall prevalence of MetS in our Gaza Strip cohort was 23.0% and 39.5% according to NCEP/ATP III and IDF definitions respectively (pdefinition (mean 3.42 ± 0.63 vs 3.52 ± 0.69 respectively, p=0.865). Both IDF and NCEP/ATP III showed an increased prevalence of MetS with age, and body mass index (BMI), however they revealed different prevalence trends with sex. Except for BMI, there were no significant differences in the general and metabolic related characteristics between subjects with MetS of IDF and NCEP/ATP III definitions. Independently of the definition used, MetS is highly prevalent in Gaza Strip population, with a steady increase in MetS prevalence through age and BMI. The IDF definition tends to give higher values for MetS prevalence, and therefore could be more appropriate for diagnosing MetS in Gaza Strip cohort. Copyright © 2012 Diabetes India. Published by Elsevier Ltd. All rights reserved.

  12. Frecuencia y caracterización del síndrome metabólico según criterios de la Federación Internacional de Diabetes en familiares de primer grado de personas con diabetes tipo 1 Frequency and characterization of metabolic syndrome according to the criteria of the International Federation of Diabetes in first degree relatives of persons with type 1 diabetes

    Directory of Open Access Journals (Sweden)

    Judith Parlá Sardiñas

    2011-12-01

    Full Text Available Introducción: el síndrome metabólico se ha definido como la asociación de varios factores precursores de enfermedad cardiovascular y de diabetes mellitus tipo 2. Objetivo: determinar la frecuencia de síndrome metabólico, según los criterios de la Federación Internacional de Diabetes en familiares de primer grado de diabéticos tipo 1. Métodos: se seleccionaron 96 adultos y 97 adolescentes, se les aplicó un cuestionario, y se les realizó un examen físico general. Además, se les realizaron determinaciones en ayunas de glucosa, insulina, colesterol, triglicéridos y HDL colesterol, y se calculó el índice de resistencia a la insulina. Resultados: la frecuencia del síndrome metabólico fue mayor en los adultos 17,7 % (17/96 que en los adolescentes 3,09 % (3/97, y la resistencia a la insulina en los adultos fue similar en los sujetos con y sin síndrome metabólico. La historia familiar de enfermedad cardiovascular, diabetes mellitus tipo 2, obesidad, dislipidemia e hipertensión arterial no está asociada con la presencia del síndrome metabólico en los familiares de primer grado de diabéticos tipo 1. Conclusiones: el síndrome metabólico, según los criterios de la Federación Internacional de Diabetes, es más frecuente en los adultos que en los adolescentes familiares de primer grado de diabéticos tipo 1, y la resistencia a la insulina en estos sujetos no está exclusivamente asociada al síndrome metabólico.Introduction: the metabolic syndrome is defined as the association of some factors causing cardiovascular disease and of type 2 diabetes mellitus. Objective: to determine the frequency of the metabolic syndrome according to the criteria of the International Federation of Diabetes in first degree relatives of persons with type 1diabetes. Methods: ninety six adults and 97 adolescents were selected to apply a questionnaire and a general physical examination. Also, assessment of fast glucose, insulin, cholesterol

  13. Harmonizing the definition of the metabolic syndrome: comparison of the criteria of the Adult Treatment Panel III and the International Diabetes Federation in United States American and European populations.

    Science.gov (United States)

    Assmann, Gerd; Guerra, Rudy; Fox, Garrett; Cullen, Paul; Schulte, Helmut; Willett, DuWayne; Grundy, Scott M

    2007-02-15

    The 2 most widely used criteria to diagnose the metabolic syndrome (MS) are those developed by the United States Adult Treatment Panel III of the National Cholesterol Education Program (ATP III) and by the International Diabetes Federation (IDF). A major difference between these 2 sets of criteria is that the IDF places more emphasis on waist circumference. We compared the prevalence of MS using the ATP III and the IDF guidelines in 2 American (the Dallas Health Study and National Health and Nutrition Examination Survey) and 1 German (Prospective Cardiovascular Munster study) population samples. When the ATP III criteria were used, the prevalence of MS was higher in the United States than the German samples in both women (37% vs. 18%) and men (30% vs 25%), whereas when the IDF criteria were used, the prevalence of MS was 25% higher in the German than the American sample. Although in the United States both sets of criteria identified mostly the same people (concordance of about 90%), this was less true in Germany (concordance about 80%). To determine which criteria better predicted adverse cardiovascular outcomes, the incidence of coronary events associated with MS, as defined using the ATP III or the IDF criteria, were compared over a 10-year period among the middle-aged men in the German sample (n = 7,152). A total of 3.4% of men without MS developed an event. A much higher percentage of the men with MS defined by the ATP III criteria (10.7%) than the IDF criteria (5.5%) had a cardiovascular event. In conclusion, although the prevalence of MS was higher when the IDF criteria were used in the German sample, the IDF criteria have lower predictive power for coronary events.

  14. The Russian Federation and the International Climate Change Regime

    OpenAIRE

    GORDEEVA, Yelena

    2014-01-01

    Although the Russian Federation (RF) is one of the key players in the global climate change politics, the country is rather discreet in binding itself with new international climate obligations. Often the country is criticized for its weak national climate change law and policy. To provide current context as regards the status of Russian climate change mitigation efforts, this article analyzes the RF's climate law and policy at the domestic and international levels. It does so by first invest...

  15. Women and Diabetes

    Medline Plus

    Full Text Available ... from Other Government Agencies and Offices National Diabetes Education Program Diabetes Information on MedlinePlus Diabetes and Depression ... Emergency Preparedness International Programs News & Events Training & Continuing ... & Compliance Federal, State & Local Officials Consumers Health ...

  16. Women and Diabetes

    Medline Plus

    Full Text Available ... from Other Government Agencies and Offices National Diabetes Education Program Diabetes Information on MedlinePlus Diabetes and Depression ... Information Safety Emergency Preparedness International Programs News & Events Training & Continuing Education Inspections & Compliance Federal, State & Local Officials ...

  17. Women and Diabetes

    Medline Plus

    Full Text Available ... from Other Government Agencies and Offices National Diabetes Education Program Diabetes Information on MedlinePlus Diabetes and Depression ... Emergency Preparedness International Programs News & Events Training & Continuing Education Inspections & Compliance Federal, State & Local Officials Consumers Health ...

  18. International Geoscience Workforce Trends: More Challenges for Federal Agencies

    Science.gov (United States)

    Groat, C. G.

    2005-12-01

    Concern about the decreasing number of students entering undergraduate geoscience programs has been chronic and, at times, acute over the past three decades. Despite dwindling populations of undergraduate majors, graduate programs have remained relatively robust, bolstered by international students. With Increasing competition for graduate students by universities in Europe, Japan, Australia, and some developing countries, and with procedural challenges faced by international students seeking entry into the United States and its universities, this supply source is threatened. For corporations operating on a global scale, the opportunity to employ students from and trained in the regions in which they operate is generally a plus. For U.S. universities that have traditionally supplied this workforce, the changing situation poses challenges, but also opportunities for creative international partnerships. Federal government science agencies face more challenges than opportunities in meeting workforce needs under both present and changing education conditions. Restrictions on hiring non-U.S. citizens into the permanent workforce have been a long-standing issue for federal agencies. Exceptions are granted only where they can document the absence of eligible U.S.-citizen candidates. The U.S. Geological Survey has been successful in doing this in its Mendenhall Postdoctoral Research Fellowship Program, but there has been no solution to the broader limitation. Under current and forecast workforce recruitment conditions, creativity, such as that evidenced by the Mendenhall program,will be necessary if federal agencies are to draw from the increasingly international geoscience talent pool. With fewer U.S. citizens in U.S. geoscience graduate programs and a growing number of advanced-degreed scientists coming from universities outside the U.S., the need for changes in federal hiring policies is heightened. The near-term liklihood of this is low and combined with the decline in

  19. Federalism and decentralization: impact on international and Brazilian health policies.

    Science.gov (United States)

    Leite, Valéria Rodrigues; de Vasconcelos, Cipriano Maia; Lima, Kenio Costa

    2011-01-01

    This article discusses the implications of decentralization in the light of international and Brazilian federalism, and its effects on public health policy. In a comparative analysis among countries, the authors find there is no single model; rather, each country has a unique structure of institutions and norms that have important implications for the operation of its health system. Brazil shares some similarities with other countries that have adopted a decentralized system and is assuming features ever closer to U.S. federalism, with a complex web of relationships. The degree of inequality among Brazilian municipalities and states, along with the budgetary imbalances caused by the minimal levels of resource utilization, undermines Brazil's constitutional principles and, consequently, its federalism. To ensure the constitutional mandate in Brazil, it is essential, as in other countries, to create a stable source of funds and increase the volume and efficiency of spending. Also important are investing in the training of managers, improving information systems, strengthening the principles of autonomy and interdependence, and defining patterns of cooperation within the federation.

  20. 15th Conference of the International Federation of Classification Societies

    CERN Document Server

    Montanari, Angela; Vichi, Maurizio

    2017-01-01

    This edited volume on the latest advances in data science covers a wide range of topics in the context of data analysis and classification. In particular, it includes contributions on classification methods for high-dimensional data, clustering methods, multivariate statistical methods, and various applications. The book gathers a selection of peer-reviewed contributions presented at the Fifteenth Conference of the International Federation of Classification Societies (IFCS2015), which was hosted by the Alma Mater Studiorum, University of Bologna, from July 5 to 8, 2015.

  1. The Thalassemia International Federation: a global public health paradigm

    Directory of Open Access Journals (Sweden)

    Elpidoforos S. Soteriades

    2014-09-01

    Full Text Available Many international organizations are struggling today to coordinate limited economic and human resources in support of governments’ efforts to advance public health around the world. The United Nations and the World Health Organization, along with others play a pivotal role in this global effort. Furthermore, during the past few decades an increasingly higher percentage of global efforts on public health are carried out by specific health initiatives, international projects and non-governmental patient-oriented organizations. The Thalassemia International Federation (TIF is one such organization focusing on the control of thalassemia around the world. The current paper aims at presenting a comprehensive overview of the mission, goals, objectives and activities of this organization. Our ultimate goal is to highlight TIF’s public health paradigm and diffuse its success at an international levels for others to follow. TIF is devoted to disseminating information, knowledge, experience and best practices around the world to empower patients with thalassemia and their relatives, support health professionals providing care to such patients and promote national and international policies, which secure equal access to quality care for all patients with thalassemia.

  2. 78 FR 52532 - Exposure Draft-Standards for Internal Control in the Federal Government

    Science.gov (United States)

    2013-08-23

    ... GOVERNMENT ACCOUNTABILITY OFFICE Exposure Draft--Standards for Internal Control in the Federal... to the Standards for Internal Control in the Federal Government, known as the ``Green Book,'' under... Exposure Draft update to the Standards for Internal Control in the Federal Government reflect major...

  3. The new definition of metabolic syndrome by the international diabetes federation is less likely to identify metabolically abnormal but non-obese individuals than the definition by the revised national cholesterol education program: the Korea NHANES study.

    Science.gov (United States)

    Yoon, Y S; Lee, E S; Park, C; Lee, S; Oh, S W

    2007-03-01

    The new definitions for metabolic syndrome (MS) proposed by the IDF and revised NCEP have caused some confusion because patients have emerged that have satisfied the revised NCEP but not the IDF criteria. We performed this study to compare the prevalence of these criteria and to investigate the characteristics of discrepant cases. A total of 7962 individuals aged >or= 20 years (3597 men; 4365 women) who participated in the 1998 Korean NHANES were included. We assessed the agreement between the revised NCEP and IDF criteria and investigated the characteristics of cases satisfying the revised NCEP criteria but not the IDF criteria. The prevalence of MS by the revised NCEP (25.7% of men and 31.9% of women) was higher than that according to the IDF (14.2% of men and 26.6% of women). The IDF criteria failed to identify 44.9% of men and 16.6% of women identified as having MS according to the revised NCEP criteria. The discrepant group showed more adverse metabolic profiles and unfavorable lifestyles despite lower waist circumference as compared with those having MS by both the IDF and revised NCEP criteria. The prevalence of discrepant cases was higher among the elderly. The IDF criteria were inferior to the revised NCEP criteria in identifying the metabolically abnormal but nonobese groups known to be predisposed to type 2 diabetes and cardiovascular disease. Further research regarding the appropriateness of central obesity as an obligatory criterion proposed by the IDF seems to be warranted.

  4. 5 CFR 315.712 - Conversion based on service as a Federal Career Intern.

    Science.gov (United States)

    2010-01-01

    ... Career Intern. 315.712 Section 315.712 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL... Employment From Other Types of Employment § 315.712 Conversion based on service as a Federal Career Intern... employment, a career intern who: (1) Has successfully completed a Federal Career Intern Program, under § 213...

  5. 5th Conference of the International Federation of Classification Societies

    CERN Document Server

    Yajima, Keiji; Bock, Hans-Hermann; Ohsumi, Noboru; Tanaka, Yutaka; Baba, Yasumasa

    1998-01-01

    This volume, Data Science, Classification, and Related Methods, contains a selection of papers presented at the Fifth Conference of the International Federation of Oassification Societies (IFCS-96), which was held in Kobe, Japan, from March 27 to 30,1996. The volume covers a wide range of topics and perspectives in the growing field of data science, including theoretical and methodological advances in domains relating to data gathering, classification and clustering, exploratory and multivariate data analysis, and knowledge discovery and seeking. It gives a broad view of the state of the art and is intended for those in the scientific community who either develop new data analysis methods or gather data and use search tools for analyzing and interpreting large and complex data sets. Presenting a wide field of applications, this book is of interest not only to data analysts, mathematicians, and statisticians but also to scientists from many areas and disciplines concerned with complex data: medicine, biology, ...

  6. Incidence of Diabetes mellitus at the Federal Medical Centre Katsina ...

    African Journals Online (AJOL)

    A six-year (2002 – 2007) retrospective study of hospital records (in-patients) was carried out to investigate the incidence of Diabetes Mellitus in Katsina. The records showed that a total of 754 cases were attended within the study period. The study showed yearly increase in the incidence of the disease with the highest ...

  7. Pattern and outcome of diabetic admissions at a federal medical ...

    African Journals Online (AJOL)

    Background: Prevalence of diabetes mellitus (DM) is increasing worldwide, with the major increases expected to occur in developing countries. It has been observed that the pattern of hospital admissions can be used to determine the effectiveness of outpatient care of DM. Objective:This study was aimed to examine ...

  8. Mobile application to induce lifestyle modifications in type 2 diabetic patients: prototype based on international guidelines

    Science.gov (United States)

    García-Jaramillo, M.; Delgado, J. S.; León-Vargas, F.

    2015-12-01

    This paper describes a prototype app to induce lifestyle modifications in newly diagnosed type 2 diabetic patients. The app design is based on International Diabetes Federation guidelines and recommendations from clinical studies related to diabetes health-care. Two main approaches, lifestyle modification and self-management education are used owing to significant benefits reported. The method used is based on setting goals under medical support related to physical activity, nutritional habits and weight loss, in addition to educational messages. This is specially implemented to address the main challenges that have limited the success of similar mobile applications already validated on diabetic patients. A traffic light is used to show the overall state of the goals compliance. This state could be understood as excellent (green), there are aspects to improve (yellow), or some individual goals are not carrying out (red). An example of how works this method is presented in results. Furthermore, the app provides recommendations to the user in case the overall state was in yellow or red. The recommendations pretend to induce the user to make changes in their eating habits and physical activity. According to international guidelines and clinical studies, a prototype of mobile application to induce a lifestyle modification in order to prevent adverse risk factors related to diabetes was presented. The resulting application is apparently consistent with clinical judgments, but a formal clinical validation is required. The effectiveness of this app is currently under consideration for the Colombian population with type 2 diabetes.

  9. 78 FR 22263 - Advisory Council on the Standards for Internal Control in the Federal Government; Meeting

    Science.gov (United States)

    2013-04-15

    ... GOVERNMENT ACCOUNTABILITY OFFICE Advisory Council on the Standards for Internal Control in the... Standards for Internal Control in the Federal Government; Notice of Meeting. SUMMARY: The US Government Accountability Office (GAO) is initiating efforts to revise the Standards for Internal Control in the Federal...

  10. 78 FR 68447 - Exposure Draft-Standards for Internal Control in the Federal Government

    Science.gov (United States)

    2013-11-14

    ... GOVERNMENT ACCOUNTABILITY OFFICE Exposure Draft--Standards for Internal Control in the Federal... revisions to the Standards for Internal Control in the Federal Government, known as the ``Green Book,'' to... proposed changes contained in the 2013 Exposure Draft update to the Standards for Internal Control in the...

  11. International Field School on Permafrost: Yenisei, Russian Federation - 2013

    Science.gov (United States)

    Nyland, K. E.; Streletskiy, D. A.; Grebenets, V. I.

    2013-12-01

    The International Field School on Permafrost was established in Russia as part of International Polar Year activities. The first course was offered in 2007 in Northwestern Siberia and attracted students from Russia, Germany, and the United States. Over the past seven years undergraduate and graduate students representing eight different countries in North America, Europe, and Asia have participated in the field school. This annual summer field course visits different regions of the Russian Arctic each year, but the three course foci remain consistent, which are to make in depth examinations of, 1) natural permafrost characteristics and conditions, 2) field techniques and applications, and 3) engineering practices and construction on permafrost. During these field courses students participate in excursions to local museums and exhibitions, meet with representatives from local administrations, mining and construction industries, and learn field techniques for complex permafrost investigations, including landscape and soil descriptions, temperature monitoring, active-layer measurements, cryostratigraphy, and more. During these courses students attend an evening lecture series by their professors and also give presentations on various regionally oriented topics of interest, such as the local geology, climate, or historical development of the region. This presentation will relate this summer's (July 2013) field course which took place in the Yenisei River region of central Siberia. The course took place along a bioclimatic transect from south to north along the Yenisei River and featured extended stays in the cities of Igarka and Noril'sk. This year's students (undergraduate, masters, and one PhD student) represented universities in the United States, Canada, and the Russian Federation. The organization of this course was accomplished through the cooperation of The George Washington University's Department of Geography and the Lomonosov Moscow State University

  12. Russian Federal Nuclear Center VNIIEF - possibilities of international cooperation

    International Nuclear Information System (INIS)

    Shaburov, V.M.; Mozharov, R.V.

    2000-01-01

    The Russian Federation Nuclear Center - the All-Russian Experimental Physics Research Institute (RFNC-AREPRI; VNIIEF) is a major scientific-technical center of Russia capable of solving the most difficult problems in the interests of defense, science and the national economy. There was a time when the RFNC-AREPRI played a decisive role in liquidating the U.S. monopoly on nuclear weapons and ensuring half a century of world civilization without global political and military conflicts. Today, RFNC-AREPRI specialists are entrusted with the mission of maintaining and perfecting Russia's nuclear shield that ensures its security and independence. As well as defense-oriented projects, the Institute is busy developing and implementing a number of projects in the most diverse fields of science and technology. At present, the Institute possesses an experimental and testing base that includes: a gas dynamic complex for testing manufactured products and explosives, irradiation facilities, nuclear reactors, laser systems, complexes for mechanical, temperature and climatic testing of specific manufactured products and instruments, and an aero-ballistic testing complex. The Institute's material base, with its mathematical support, is one of the most powerful in Russia. The RFNC-AREPRI employs about 20,000 workers, including 9,500 scientists and engineers. Today, the RFNC-AREPRI is engaged in activities in the following principal directions: - properties of material under extreme pressure and temperature; - gas dynamics; - nuclear physics; - radiation physics; - laser physics and equipment; - super-powerful magnetic fields; - high-temperature plasma physics; - development of physical models of complex physical processes and the creation of mathematical methodologies and software based on these models; - energy; - medicine; - ecology; - progressive technologies for various sectors of the economy. International cooperation of the RFNC-AREPRI is reviewed. (authors)

  13. "KiDS and Diabetes in Schools" project: Experience with an international educational intervention among parents and school professionals.

    Science.gov (United States)

    Bechara, Glaucia Margonari; Castelo Branco, Fernanda; Rodrigues, Avelino Luiz; Chinnici, Daniela; Chaney, David; Calliari, Luis Eduardo P; Franco, Denise Reis

    2018-03-04

    Although it is known that school care is a major challenge in diabetes treatment, there is still no published international initiative. The aims of this study were to introduce an international educational intervention tool, the International Diabetes Federation (IDF) KiDS and Diabetes in Schools project (KiDS project), and to describe its impact on diabetes knowledge and behavior of caregivers and school professionals. The KiDS project was developed with the support of IDF and the International Society for Pediatric and Adolescent Diabetes and provides online free material in 10 languages, directed to caregivers and school personnel. A pilot evaluation of the KiDS intervention was performed in Brazil. An educational intervention was conducted in 5 primary schools, with 42 parents and school staff, followed by 2 individual interviews after 1 and 3 months. The results were evaluated in a qualitative study with a descriptive design based on content analysis. School staff acquired new knowledge on diabetes and its treatment. They felt more confident when helping students with diabetes and said the educational intervention promoted a positive impact on the teacher-student relationship, on the caring for health, and on school infrastructure. Family members of children with diabetes stated that the educational intervention gave them an opportunity to strengthen and update information on treatment and improve their knowledge. The KiDS project is the first international tool directed to foster a safe and supportive environment and a better understanding of diabetes in schools. In this pilot evaluation, it achieved the goal of informing and changing the behavior of parents and school staff, thus improving the care provided to children with diabetes in schools. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  14. Van jaarcontrole naar jaargesprek : Zorg op maat voor mensen met diabetes

    NARCIS (Netherlands)

    Rutten, Guy E H M; Van Vugt, Heidi A.; De Weerdt, Inge; Lamberts, Steven W J; De Koning, Eelco J P

    2016-01-01

    Diabetes care is shifting from disease management to personalised care. Internationally, diabetes care providers are advised to integrate the patient's preferences, wishes and possibilities into diabetes care in order to improve its efficiency. The Dutch Diabetes Federation has developed a

  15. Frecuencia y caracterización del síndrome metabólico según criterios de la Federación Internacional de Diabetes en familiares de primer grado de personas con diabetes tipo 1 Frequency and characterization of metabolic syndrome according to the criteria of the International Federation of Diabetes in first degree relatives of persons with type 1 diabetes

    OpenAIRE

    Judith Parlá Sardiñas; Eduardo Cabrera Rode; Sigrid Marichal Madrazo; Celeste Arranz Calzado; Emma Domínguez Alonso; Pedro González Fernández; Manuel Vera González

    2011-01-01

    Introducción: el síndrome metabólico se ha definido como la asociación de varios factores precursores de enfermedad cardiovascular y de diabetes mellitus tipo 2. Objetivo: determinar la frecuencia de síndrome metabólico, según los criterios de la Federación Internacional de Diabetes en familiares de primer grado de diabéticos tipo 1. Métodos: se seleccionaron 96 adultos y 97 adolescentes, se les aplicó un cuestionario, y se les realizó un examen físico general. Además, se les realizaron deter...

  16. Matching diagnosis and management of diabetes in pregnancy to local priorities and resources: an international approach.

    Science.gov (United States)

    McIntyre, H David; Oats, Jeremy J N; Zeck, Willibald; Seshiah, V; Hod, Moshe

    2011-11-01

    The International Association of the Diabetes and Pregnancy Study Groups' (IADPSG) criteria for the diagnosis and classification of hyperglycemia in pregnancy are described and application of these in differing healthcare contexts on a worldwide basis is reported. Existing local protocols and known epidemiologic and clinical data regarding the detection and management of overt diabetes and gestational diabetes in the context of human pregnancy are considered. Although the IADPSG criteria are uniform, their introduction poses a variety of practical and technical challenges in differing healthcare contexts, both between and within countries. Knowledge of local factors will be vital in the implementation of the new guidelines and will require extensive liaison with local clinical and health policy groups. Resource availability will be critical in determining the type of treatment available in this context. The IADPSG criteria offer an important opportunity for a uniform approach to diabetes in pregnancy. Scaled implementation of these criteria adapted to a variety of local healthcare contexts should improve both research endeavors and patient care. Copyright © 2011 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd.. All rights reserved.

  17. Internal Auditing in Federal, State, and Local Governments (Part II).

    Science.gov (United States)

    Knight, Susan; Wilson, Guy

    1981-01-01

    This second part of an annotated bibliography of reports, books, and journal articles concerned with internal auditing in government contexts reviews the available literature for an understanding of the types of internal audit, methods and practices, and other facets. (FM)

  18. Govt. Pubs.: Internal Auditing in Federal, State, and Local Governments.

    Science.gov (United States)

    Knight, Susan; Wilson, Guy

    1980-01-01

    Lists reports, monographs, and journal articles of the last five years that deal with internal auditing at various governmental levels, including the growth of the internal audit, the development of guidelines, current practices, types of audit, and current issues. (FM)

  19. The Russian Federation legislation. The new laws. Prospects for international cooperation

    International Nuclear Information System (INIS)

    Lebedev, A. YE.

    2002-01-01

    Survey of the regulatory basis for the international cooperation of the Russian Federation in the area of foreign commercial and research spent fuel management. Analysis of the latest legislative amendments. Complex approach and environmental priorities of the new legislative initiatives (three Federal laws): Amendments to Articles 1, 47 and 64 of the Federal Law on U tilization of atomic energy ; Amendments to Articles 50 of the Federal Law on E nvironmental protection ; The new Federal Law O n Special ecological programs for the clean- up of areas, contaminated by radiation . (author)

  20. PANCREATIC DIABETES TYPE 2 IN CHILDREN AND ADOLESCENTS: INTERNATIONAL RECOMMENDATIONS

    Directory of Open Access Journals (Sweden)

    O.V. Vasyukova

    2009-01-01

    Full Text Available Violent growth of type 2 diabetes mellitus (DM morbidity in children and adolescents is spread all around the world. Peculiarities of DM type 2 in this age group are: absence of determined diagnostic criteria, difficulty of differential diagnosis with DM type 1, early development of complications. International Society of Pediatric and Adolescent Diabetes propose Guideline of DM type 2 management, which consider main questions of diagnostics, treatment and prophylaxis of this disease. The agent of choice for treatment of DM type 2 in children upwards 10 years is metformin.Key words: children, diabetes mellitus type 2, diagnostics, treatment.(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(2:49-53

  1. 78 FR 40740 - Advisory Council on the Standards for Internal Control in the Federal Government

    Science.gov (United States)

    2013-07-08

    ... GOVERNMENT ACCOUNTABILITY OFFICE Advisory Council on the Standards for Internal Control in the... on the Green Book Advisory Council and the Standards for Internal Control in the Federal Government.... SUMMARY: The US Government Accountability Office (GAO) is preparing to revise the Standards for Internal...

  2. The international economic position of the Federal Republic of Germany

    International Nuclear Information System (INIS)

    Strube, J.

    1993-01-01

    In spite of a clear increase in the domestic demands the German industry has been investing about 175 billion marks abroad during the past decade. These investments abroad have not necessarily been undermining the economic status of the Federal Republic of Germany but can rather be explained by the importance of the market proximity to foreign locations. In the first place, the German industry's foreign investments reveal the efficiency and competiveness of the companies which have been succeeding in establishing themselves on the markets in Europe and outside of Europe and in qualifying the domestic industry for the world market. (orig.) [de

  3. From Individuals to International Policy: Achievements and Ongoing Needs in Diabetes Advocacy.

    Science.gov (United States)

    Hilliard, Marisa E; Oser, Sean M; Close, Kelly L; Liu, Nancy F; Hood, Korey K; Anderson, Barbara J

    2015-09-01

    Diabetes impacts tens of millions of people in the United States of America and 9 % of the worldwide population. Given the public health implications and economic burden of diabetes, the needs of people with diabetes must be addressed through strategic and effective advocacy efforts. Diabetes advocacy aims to increase public awareness about diabetes, raise funds for research and care, influence policy impacting people with diabetes, and promote optimal individual outcomes. We present a framework for diabetes advocacy activities by individuals and at the community, national, and international levels and identify challenges and gaps in current diabetes advocacy. Various groups have organized successful diabetes advocacy campaigns toward these goals, and lessons for further advancing diabetes advocacy can be learned from other health-related populations. Finally, we discuss the role of healthcare providers and mental/behavioral health professionals in advocacy efforts that can benefit their patients and the broader population of people with diabetes.

  4. Communication of 24 April 2000 received from the Permanent Mission of the Russian Federation to the International Atomic Energy Agency

    International Nuclear Information System (INIS)

    2000-01-01

    The document reproduces the text of the Communication of 24 April 2000 received from the Permanent Mission of the Russian Federation to the International Atomic Energy Agency, including a statement by the Ministry of Foreign Affairs of the Russian Federation in connection with the ratification by the State Duma of the Federal Assembly of the Russian Federation of the Comprehensive Nuclear Test Ban Treaty

  5. [Interpretation of the International Joint Statement on Metabolic Surgery in the Treatment Algorithm for Type 2 Diabetes].

    Science.gov (United States)

    Zhang, Peng; Zheng, Chengzhu

    2017-04-25

    Along with the soaring prevalence of obesity and type 2 diabetes mellitus (T2DM) globally, metabolic and bariatric surgery (MBS) has been rapidly developing into a major surgical subspecialty. However, the indications, benefits and potential risks of MBS are still controversial so far. In September 2015, the 2nd Diabetes Surgery Summit (DSS-II() was successfully convened, and later on an international joint statement on metabolic surgery in the treatment algorithm for T2DM was released based upon the consensus reached in DSS-II(, aiming to serve as a new global clinical guideline. The DSS-II( joint statement was initiated and endorsed by 5 leading international diabetes organizations, including American Diabetes Association (ADA), International Diabetes Federation (IDF), Chinese Diabetes Society (CDS), Diabetes India, as well as Diabetes UK, and was developed by an expert committee comprised of 48 international authorities as voting delegates. Up to the date of publication, the DSS-II( statement has been officially endorsed by 45 international professional associations/societies, including 30 non-surgical and 15 surgical organizations. In this statement, the following six aspects were recommended to differentiate MBS from traditional bariatric surgery: 1)The primary goal of MBS is to treat T2DM and to reduce the risk of T2DM complications; 2) In addition to a 50% or more of excess weight loss and normalization of glycemia, outcomes of diabetes complications should also be considered as clinical endpoints of MBS; 3) For patient selection, body mass index (BMI), T2DM treatment, as well as long-term risks versus benefits, including its effects on cardiovascular events (CVD), should all be considered; 4) T2DM and its complications, as well as pancreatic function reserve should be assessed pre-operatively; 5) Major surgical options include laparoscopic Roux-en-Y gastric bypass (LRYGB), laparoscopic sleeve gastrectomy (LSG), laparoscopic adjustable gastric banding (LAGB

  6. Building on the International Polar Year: Discovering Interdisciplinary Data Through Federated Search

    Directory of Open Access Journals (Sweden)

    L Yarmey

    2014-10-01

    Full Text Available The legacy of the International Polar Year 2007–2008 (IPY includes advances in open data and meaningful progress towards interoperability of data, systems, and standards. Enabled by metadata brokering technologies and by the growing adoption of international metadata standards, federated data search welcomes diversity in Arctic data and recognizes the value of expertise in community data repositories. Federated search enables specialized data holdings to be discovered by broader audiences and complements the role of metadata registries such as the Global Change Master Directory, providing interoperability across the Arctic web-of-repositories.

  7. PREVALENCE OF DIABETIC RETINOPATHY IN PATIENT TYPE 2 DIABETES MELLITUS AT INTERNAL MEDICINE POLICLINIC SANGLAH HOSPITAL

    Directory of Open Access Journals (Sweden)

    Ni Made Sintia Anggia Sari

    2013-05-01

    Full Text Available Normal 0 false false false EN-US X-NONE X-NONE One of the complications that can occur in microvaskular diabetes mellitus is diabetic retinopathy. This research was carried out to know the prevalence of diabetic retinopathy in patients type 2 diabetes mellitus at internal divison of Sanglah Hospital. The method used is cross sectional by collecting data from the questionnaire and secondary data of medical record patient's type 2 DM. On this research acquired 111 patients (35.1% with diabetic retinopathy and (64,9% nonretinopathy. In the group with good level of HbA1c (<6.5% the prevalence of diabetic retinopathy obtained 53.2%, in the group of patients with moderate level of HbA1c (6.5-8% as much as 22.5%, and in the group of patients with HbA1c bad level (>8% as much as 24.3%. The prevalence of the occurrence of DM complications in the diabetic retinopathy is still high, and a good level of HbA1c does not guarantee a person can’t have complication because the complication can also happens are affected by hypertension, dyslipidemia, age, and duration of DM. /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin-top:0in; mso-para-margin-right:0in; mso-para-margin-bottom:10.0pt; mso-para-margin-left:0in; line-height:115%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;}

  8. Civil Legislation and International Treaties: The Interaction within the Legal System of the Russian Federation

    OpenAIRE

    Eremenko, Alexander

    2010-01-01

    The article deals with analysis of theoretical aspects of the category of “international treaties” from the point of view of their place in the hierarchical structure of the legal system of the Russian Federation and their correlation to the civil legislation. The author describes the synthetic models of correlation of international treaties and national legislation and formulates these models as concepts of “super-nationalism”, “sub-constitutionalism”, “super-legalism” and “inter-legalism”....

  9. DEVELOPMENT STRATEGY OF INTERNATIONAL HUBS BASED ON REGIONAL AIRPORTS IN RUSSIAN FEDERATION

    Directory of Open Access Journals (Sweden)

    I. A. Belavintsev

    2014-01-01

    Full Text Available The article deals with an important area of development of the civil aviation airports network and air transport route networks in the Russian Federation and is based on priority development of the largest airport hubs considering the specific characteristics of the current status and further development of internal air transport market and subsidy programs of the Russian regional aircraft.

  10. Service Quality and Satisfaction Perspectives at the 2011 International Amateur Athletic Federation (IAAF) World Championships

    Science.gov (United States)

    Kim, Min Kil; Kim, Suk-Kyu; Lee, Donghun; Judge, Lawrence W.; Huang, Haiyan

    2013-01-01

    The purpose of this exploratory study was to identify and analyze the factors that contribute to perceived service quality, user satisfaction, and behavioral intention in covering megasporting events at the Main Media Center for the International Amateur Athletic Federation (IAAF) Track and Field World Championships. The data were collected…

  11. The Rise of International Relations Programs in the Brazilian Federal Universities: Curriculum Specificities and Current Challenges

    Science.gov (United States)

    Ferreira, Marcos Alan S. V.

    2016-01-01

    The aim of this reflection is to study the new international relations (IR) programs introduced by Brazilian federal universities, looking comparatively at their curriculum specificities and current challenges. In recent years, Brazil has seen an increase of IR programs launched in several regions. Since 2003, the Ministry of Education is in the…

  12. Women and Diabetes

    Medline Plus

    Full Text Available ... sugar. Follow Us on Twitter There is good news. Diabetes can be controlled by maintaining a healthy ... Committees Regulatory Information Safety Emergency Preparedness International Programs News & Events Training & Continuing Education Inspections & Compliance Federal, State & ...

  13. Routine monitoring of diabetes mellitus in adults at primary health ...

    African Journals Online (AJOL)

    Most of the recommendations included here are based on the Society for Endocrinology,. Metabolism and Diabetes of South Africa. (SEMDSA) guidelines for type 2 diabetes, and on those of the International Diabetes. Federation (IDF) and the American Diabetes. Association (ADA).1-3 Guidelines for diabetes management ...

  14. Communication of 17 April 2000 received from the Permanent Mission of the Russian Federation to the International Atomic Energy Agency

    International Nuclear Information System (INIS)

    2000-01-01

    The document reproduces the text of the Communication of 17 April 2000 received from the Permanent Mission of the Russian Federation to the International Atomic Energy Agency, including a statement by the Acting President of the Russian Federation in connection with the ratification by the State Duma of the Federal Assembly of the Russian Federation of START-II Treaty and the package agreements on antimissile defence of 1997

  15. Achieving International Society for Pediatric and Adolescent Diabetes and American Diabetes Association clinical guidelines offers cardiorenal protection for youth with type 1 diabetes.

    Science.gov (United States)

    Bjornstad, Petter; Pyle, Laura; Nguyen, Nhung; Snell-Bergeon, Janet K; Bishop, Franziska K; Wadwa, R Paul; Maahs, David M

    2015-02-01

    Most youth with type 1 diabetes do not meet the American Diabetes Association (ADA) and International Society for Pediatric and Adolescent Diabetes (ISPAD) targets for hemoglobin A1c (HbA1c), blood pressure (BP), lipids, and body mass index (BMI). We hypothesized that ISPAD/ADA goal achievement at baseline would be associated with cardiorenal risk factors at baseline and 2 yr follow-up in adolescents with type 1 diabetes. We assessed the cross-sectional and longitudinal relationships between ISPAD/ADA goal achievement at baseline and cardiorenal health at baseline and 2-yr follow-up (n = 297; 15.4 ± 2.1 yr at baseline) in adolescents with type 1 diabetes. Goal achievement was defined as HbA1c 35 mg/dL, triglycerides (TG) Adolescents with type 1 diabetes who met 1-3 goals, had significantly greater (P goals after adjusting for Tanner stage, sex, age, and diabetes duration. No statistically significant differences in the cardiorenal outcomes were observed between adolescents with type 1 diabetes who met 4-6 goals and non-diabetic controls (n = 96). In adolescents with type 1 diabetes, baseline ADA/ISPAD goal achievement was associated with cardiorenal protection at baseline and 2-yr follow-up. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  16. 5th European Conference of the International Federation for Medical and Biological Engineering

    CERN Document Server

    European IFMBE MBEC : Cooperation for Effective Healthcare

    2012-01-01

    This volume presents the 5th European Conference of the International Federation for Medical and Biological Engineering (EMBEC),  held in Budapest, 14-18 September, 2011. The scientific discussion on the conference and in this conference proceedings include the following issues: - Signal & Image Processing - ICT - Clinical Engineering and Applications - Biomechanics and Fluid Biomechanics - Biomaterials and Tissue Repair - Innovations and Nanotechnology - Modeling and Simulation - Education and Professional

  17. International Federation for Emergency Medicine model curriculum for medical student education in emergency medicine.

    Science.gov (United States)

    Hobgood, Cherri; Anantharaman, Venkataraman; Bandiera, Glen; Cameron, Peter; Halpern, Pinchas; Holliman, James; Jouriles, Nicholas; Kilroy, Darren; Mulligan, Terrence; Singer, Andrew

    2010-10-01

    Currently, there is no internationally recognised, standard curriculum that defines the basic minimum standards for emergency medicine education. To address this, the International Federation for Emergency Medicine convened a committee of international experts in emergency medicine and international emergency medicine development to outline a global curriculum for medical students in emergency medicine. This curriculum document represents the consensus of recommendations by this committee. The curriculum is designed with a focus on the basic minimum emergency medicine educational content that any medical school should be delivering to its students during their undergraduate years of training. The content is relevant not just for communities with mature emergency medicine systems, but also for developing nations or for nations seeking to expand emergency medicine within current educational structures. It is anticipated that there will be wide variability in how this curriculum is implemented and taught, reflecting the existing educational milieu, the resources available and the goals of the institutions' educational leadership.

  18. The diabetes healthy outcomes program: results of free health care for uninsured at a federally qualified community health center.

    Science.gov (United States)

    Belue, Rhonda; Figaro, M Kathleen; Peterson, Jeannine; Wilds, Christina; William, Parnitha

    2014-01-01

    Uninsured patients with diabetes are at increased risk for poor outcomes and often have limited access to health and prescription services necessary to manage diabetes. Hamilton Health Center, a federally qualified community health center, with support from the Highmark Foundation, implemented a Diabetes Healthy Outcomes Program (DHOP) for uninsured patients. To evaluate the effectiveness of DHOP that is designed to provide health care and supportive services for uninsured diabetic patients at a federally qualified community health center. Mixed quantitative and qualitative analyses of participant outcomes and satisfaction were used to assess program effectiveness. A total of 189 participants enrolled in DHOP over 2 years. Thirty-four (18%) participants had adequate glycemic control with hemoglobin A1c (HbA1c) ≤ 7%. Overall, 105 participants received prescription drugs, 101 participants received eye care services, 23 participants received dental services, 45 received podiatry services, 37 received nutrition services, and 28 patients engaged in an exercise program. More participants (38%, 34) had controlled diabetes mellitus at study start than at the end (28%, 25). However, 30% versus 17% of participants with 2 HbA1c measurements achieved or maintained HbA1c ≤ 7% by the end of the program compared with the start. Participants who accessed more services were more likely to achieve glycemic control as measured by HbA1c (P > .01). Although 30% of participants improved or maintained glycemic control over 2 years, more were uncontrolled at the end than at study start. Participants who accessed more primary and specialty care services were more likely to achieve glycemic control. Multidisciplinary care may improve diabetes control in low-income patients.

  19. PingFederate

    Data.gov (United States)

    US Agency for International Development — PingFederate Server provides Identity Federation and Single Sign On Capabilities. Federated identity management (or identity federation) enables enterprises to...

  20. The Russian Federation and the International Space Station: Leveraging Russian Space Strengths to Control its Missile Technology Proliferation

    National Research Council Canada - National Science Library

    Gloss, Lawrence

    1998-01-01

    .... This thesis discusses how a partnership with the Russian Federation and Russian Space Agency within the International Space Station can both act as an incentive for the Russians to prevent illicit...

  1. Internal Communication in the Public Management: The Case of a Brazilian Federal Public Authority

    Directory of Open Access Journals (Sweden)

    Priscila Reinaldo Marson

    2013-03-01

    Full Text Available The intention of this article is to present a case study on the adoption and use of new channels of internal communication in a federal public autarchy. The study was conducted at the National Institute of Social Security, in São Paulo, between July 2008 and July 2009, and aimed to monitor the period in which a new internal communication plan was developed and implemented in its initial phase. The research methodology used was the case study, consisting of documentary analysis, field research and in-depth interviews conducted with the institution’s public employees. As a result, it was possible to observe the internal resistance and the difficulties encountered in the management of the new plan. Among its conclusions, the study highlights the need for a previous study on the conditions of relationships and practices developed in a public service unit at the adoption of new communication tools. It also highlights the importance of planning and management actions in the implementation of the intended communication actions, including internal marketing efforts to sensitize users about the meaning and importance of internal communication in promoting greater agility and efficiency in the workplace, in order to offer best public services to users.

  2. Diabetes - resources

    Science.gov (United States)

    Resources - diabetes ... The following sites provide further information on diabetes: American Diabetes Association -- www.diabetes.org Juvenile Diabetes Research Foundation International -- www.jdrf.org National Center for Chronic Disease Prevention and Health Promotion -- ...

  3. From France to the World: The International Federation of Organic Agriculture Movements (IFOAM

    Directory of Open Access Journals (Sweden)

    John Paull

    2010-12-01

    Full Text Available The formation of the International Federation of Organic Agriculture Movements (IFOAM at Versailles, France, in 1972 set organic food and farming on a strong future trajectory. It was an initiative of France’s Nature et Progrès, and driven by its then President, Roland Chevriot. IFOAM was founded with the support of a small cluster of kindred organisations: Rodale Press of the USA; the Soil Association of the UK; the Soil Association of South Africa; and the Swedish Biodynamic Association. None of these five organisations bore the term ‘organic’ in their title, nevertheless, the choice of name acknowledged ‘organic’ as the term to signify their common cause. It secured ‘organic’ as the core narrative element and as the international descriptor of what is now a clearly identifiable and differentiated segment of the global food and farming sector. From the outset ‘biodynamic’ was accepted as a special case of ‘organic’. The formation of IFOAM created an entity which united the aspirations, the philosophies and the hopes of disparate groups each with roles primarily restricted to national advocacy. IFOAM has grown to a federation of 804 organisations from 111 counties. Organic production statistics are now reported by IFOAM from 154 countries and organic sector retail sales are reported to be US$51b annually. IFOAM is based in Bonn, Germany, and as the global umbrella advocacy group for the organic sector it is without peer.

  4. International Federation for Emergency Medicine model curriculum for emergency medicine specialists

    Directory of Open Access Journals (Sweden)

    Cherri Hobgood

    2011-06-01

    Full Text Available To meet a critical and growing need for emergency physicians and emergency medicine resources worldwide, physicians must be trained to deliver time-sensitive interventions and lifesaving emergency care. Currently, there is no globally recognized, standard curriculum that defines the basic minimum standards for specialist trainees in emergency medicine. To address this deficit, the International Federation for Emergency Medicine (IFEM convened a committee of international physicians, health professionals, and other experts in emergency medicine and international emergency medicine development to outline a curriculum for training of specialists in emergency medicine. This curriculum document represents the consensus of recommendations by this committee. The curriculum is designed to provide a framework for educational programs in emergency medicine. The focus is on the basic minimum emergency medicine educational content that any emergency medicine physician specialist should be prepared to deliver on completion of a training program. It is designed not to be prescriptive but to assist educators and emergency medicine leadership to advance physician education in basic emergency medicine no matter the training venue. The content of this curriculum is relevant not just for communities with mature emergency medicine systems but in particular for developing nations or for nations seeking to expand emergency medicine within the current educational structure. We anticipate that there will be wide variability in how this curriculum is implemented and taught. This variability will reflect the existing educational milieu, the resources available, and the goals of the institutions’ educational leadership with regard to the training of emergency medicine specialists.

  5. Brave and angry--the creation and development of the International Planned Parenthood Federation (IPPF).

    Science.gov (United States)

    Claeys, Vicky

    2010-12-01

    This paper looks back on the developments in thinking from birth control, through voluntary family planning, to a comprehensive approach to sexual and reproductive health and rights (SRHR), and celebrates some of the key players in this evolution. It tells the story of the creation of the International Planned Parenthood Federation (IPPF) in 1952, and scrutinises how important this organisation was then and is now. It gives an idea of the efforts it took to reassemble initiatives around the world into one body, strong enough to foster the cause to the benefit of all. While IPPF was and still is a unique association, it has increased its partnerships and works together with a multitude of organisations active in the field of SRHR. In the current political context joint efforts are still needed to protect the universally recognised human right of people to decide freely and responsibly on the number and spacing of their children, and their access to adequate education and information.

  6. 6th European Conference of the International Federation for Medical and Biological Engineering

    CERN Document Server

    Vasic, Darko

    2015-01-01

    This volume presents the Proceedings of the 6th European Conference of the International Federation for Medical and Biological Engineering (MBEC2014), held in Dubrovnik September 7 – 11, 2014. The general theme of MBEC 2014 is "Towards new horizons in biomedical engineering" The scientific discussions in these conference proceedings include the following themes: - Biomedical Signal Processing - Biomedical Imaging and Image Processing - Biosensors and Bioinstrumentation - Bio-Micro/Nano Technologies - Biomaterials - Biomechanics, Robotics and Minimally Invasive Surgery - Cardiovascular, Respiratory and Endocrine Systems Engineering - Neural and Rehabilitation Engineering - Molecular, Cellular and Tissue Engineering - Bioinformatics and Computational Biology - Clinical Engineering and Health Technology Assessment - Health Informatics, E-Health and Telemedicine - Biomedical Engineering Education

  7. IPPF Charter on Sexual and Reproductive Rights. International Planned Parenthood Federation.

    Science.gov (United States)

    Newman, K; Helzner, J F

    1999-05-01

    For most of human existence and in most societies, women have been considered to be property and subject to men. Throughout history, with such notable exceptions as Queen Boadicea, Eleanor of Aquitaine, Elizabeth I of England, and Catherine the Great of Russia, women had little or no power until early in the 20th century when the women's suffrage movement was successful in the United States and in some European countries. As women have gained political rights, groups of women have sought sexual and reproductive rights, as exemplified by the feminist movement of the past few decades in the United States. Although marked strides toward achievement of reproductive choice have been taken in high-income countries, there remain major strictures to reproductive freedom for women in low-income countries. This area, which is replete with ethical and moral issues, has been addressed by the International Planned Parenthood Foundation (IPPF), which has worked to improve the sexual and reproductive health of women throughout the world. The IPPF Charter on Sexual and Reproductive Rights is a paradigm for both women's rights and human rights. Karen Newman is policy adviser with the IPPF and has codrafted the IPPF Charter on Sexual and Reproductive Rights together with two lawyers. She has held several positions within the IPPF, including medical researcher, press officer, and programme adviser in Europe, where she had responsibility for working with new family planning associations (FPAs) in the Czech Republic and Slovakia. At present, she is working to increase the capacity of IPPF member FPAs to undertake human rights-based advocacy for sexual and reproductive health and rights. Judith F. Helzner is director of Sexual and Reproductive Health at International Planned Parenthood Federation/Western Hemisphere Region, Inc., where she has worked since 1987. She holds M.A. degrees from the University of Pennsylvania in International Relations and Demography. Her previous employment

  8. 76 FR 54287 - Notice of Intent To Release Federally-Obligated Airport Properties, Tampa International Airport...

    Science.gov (United States)

    2011-08-31

    ...-aeronautical use. The property will be released of its federal obligations for fair market value. The fair... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Notice of Intent To Release Federally-Obligated Airport Properties, Tampa...

  9. Diabetes education program for people with type 2 diabetes: An international perspective.

    Science.gov (United States)

    Rashed, Osama A; Sabbah, Haleama Al; Younis, Mustafa Z; Kisa, Adnan; Parkash, Jai

    2016-06-01

    In the Palestinian community, lifestyle changes, rapid urbanization and socioeconomic development, stress, smoking, and changes in food habits has increased the risk of non-communicable diseases especially diabetes mellitus. Diabetes complications can be prevented if the glycemic status of patients with diabetes is maintained within a nearly normal range. Therefore, patient education is critical in controlling blood glucose levels within the normal range. This study aimed at measuring the effect of diabetes educational intervention program for patients suffering from type 2 diabetes attending the Diabetes Clinic in Tulkarim Directorate of Health. A short duration observational study involving pre- and post-test educational intervention program was carried out on a relatively small number of type 2 diabetes patients at the Diabetes Clinic in Tulkarim Directorate of Health. In total, 215 patients attended a group-based 4h educational intervention session about diabetes. The program included explaining diabetes mellitus-symptoms, risk factors, types, treatment and complications and main aspects of self-care of the disease (foot care, eye care, and blood glucose monitoring), main aspects of dietary management, weight reduction, blood pressure, smoking cessation, periodic investigations, home monitoring and importance of physical activity. Knowledge evaluation questionnaire were evaluated pre- and post-study. Anthropometric measurements such as body weight (WT), body mass index (BMI) and laboratory tests such as fasting blood glucose (FBG), hemoglobin A1C (HbA1c), cholesterol (Chol), and triglycerides (TG) were measured both at the beginning and at the end of the study. Significance of the results was assessed by paired t-test at 95% confidence interval. The participant's mean age was 51.07 that ranged between 31 and 70 years. For a total of 215 participants, 41.4% were males and 58.6% were females. The mean weight before educational intervention was 80.81±14.95kg (82

  10. Condições periodontais em portadores de diabetes mellitus tipo 2 atendidos na Universidade Federal da Paraíba = Periodontal conditions in carriers of diabetes mellitus type 2 assisted in the Federal University of Paraíba

    Directory of Open Access Journals (Sweden)

    Guimarães, Karis Barbosa

    2007-01-01

    Full Text Available Este estudo propôs avaliar as condições periodontais e sua relação com o diabetes mellitus, através da análise clínica do grau de comprometimento dos tecidos de proteção e sustentação dentários. Foram examinados 71 pacientes, de ambos os gêneros e na faixa etária de 31 a 90 anos, portadores de Diabetes Mellitus Tipo 2 atendidos na Clínica de Estomatologia e Hospital Universitário da Universidade Federal da Paraíba, João Pessoa/PB. O critério de exclusão da amostra foi definido pelo edentulismo total. O índice periodontal comunitário modificado (com análise total dos elementos dentais presentes na cavidade oral e o índice de perda de inserção periodontal determinaram as condições periodontais. O diagnóstico de diabetes mellitus foi estabelecido através da glicemia de jejum e de duas horas após sobrecarga com 75 g de glicose. Para análise estatística descritiva utilizou-se o programa SPSS v. 11. 5. Quanto às condições periodontais, observou-se que 57,8% dos indivíduos apresentaram sangramento à sondagem, 71,8% presença de cálculo, 3,63% bolsas superficiais e 0,28% bolsas profundas. Perdas de inserção periodontal maiores que 6 mm foram observadas em 3,0% dos indivíduos. Não foi observada associação estatisticamente significante entre diabetes e condições periodontais, embora indivíduos com diabetes tenham maior susceptibilidade a desenvolverem bolsas profundas. Conclui-se que a abordagem epidemiológica da condição periodontal e sua associação com doenças sistêmicas, como o diabetes mellitus, pode oferecer importante contribuição para prevenir suas complicações

  11. Disparities in psychosocial cancer care: a report from the International Federation of Psycho-oncology Societies.

    Science.gov (United States)

    Grassi, Luigi; Fujisawa, Daisuke; Odyio, Philip; Asuzu, Chioma; Ashley, Laura; Bultz, Barry; Travado, Luzia; Fielding, Richard

    2016-10-01

    The aim of the study was to understand the characteristics of the International Federation of Psycho-oncology Societies (FPOS) and possible disparities in providing psychosocial care in countries where psycho-oncology societies exist. A survey was conducted among 29 leaders of 28 countries represented within the FPOS by using a questionnaire covering (i) characteristics of the society; (ii) characteristics of the national health care system; (iii) level of implementation of psycho-oncology; and (iv) main problems of psycho-oncology in the country. Twenty-six (90%) FPOS returned the questionnaires. One-third reported to have links with and support from their government, while almost all had links with other scientific societies. The FPOS varied in their composition of members' professions. Psychosocial care provision was covered by state-funded health services in a minority of countries. Disparities between countries arose from different causes and were problematic in some parts of the world (eg, Africa and SE Asia). Elsewhere (eg, Southern Europe and Eastern Europe), austerity policies were reportedly responsible for resource shortages with negative consequences on psychosocial cancer care. Half of FPOS rated themselves to be integrated into mainstream provision of care, although lack of funding was the most common complain. The development and implementation of psycho-oncology is fragmented and undeveloped, particularly in some parts of the world. More effort is needed at national level by strong coalitions with oncology societies, better national research initiatives, cancer plans, and patient advocacy, as well as by stronger partnership with international organizations (eg, World Health Organization and Union for International Cancer Control). Copyright © 2016 John Wiley & Sons, Ltd.

  12. International Federation for Emergency Medicine Model Curriculum for Emergency Medicine Specialists.

    Science.gov (United States)

    Hobgood, Cherri; Anantharaman, Venkataraman; Bandiera, Glen; Cameron, Peter; Halpern, Pinchas; Holliman, C James; Jouriles, Nicholas; Kilroy, Darren; Mulligan, Terrence; Singer, Andrew

    2011-10-01

    To meet a critical and growing need for emergency physicians and emergency medicine resources worldwide, physicians must be trained to deliver time-sensitive interventions and lifesaving emergency care. Currently, there is no globally recognized, standard curriculum that defines the basic minimum standards for specialist trainees in emergency medicine. To address this deficit, the International Federation for Emergency Medicine convened a committee of international physicians, health professionals and other experts in emergency medicine and international emergency medicine development to outline a curriculum for training of specialists in emergency medicine. This curriculum document represents the consensus of recommendations by this committee. The curriculum is designed to provide a framework for educational programmes in emergency medicine. The focus is on the basic minimum emergency medicine educational content that any emergency medicine physician specialist should be prepared to deliver on completion of a training programme. It is designed not to be prescriptive but to assist educators and emergency medicine leadership to advance physician education in basic emergency medicine no matter the training venue. The content of this curriculum is relevant not just for communities with mature emergency medicine systems, but in particular for developing nations or for nations seeking to expand emergency medicine within the current educational structure. We anticipate that there will be wide variability in how this curriculum is implemented and taught. This variability will reflect the existing educational milieu, the resources available, and the goals of the institutions' educational leadership with regard to the training of emergency medicine specialists. © 2011 The Authors. EMA © 2011 Australasian College for Emergency Medicine and Australasian Society for Emergency Medicine.

  13. Diabetes mellitus in older people: position statement on behalf of the International Association of Gerontology and Geriatrics (IAGG), the European Diabetes Working Party for Older People (EDWPOP), and the International Task Force of Experts in Diabetes.

    Science.gov (United States)

    Sinclair, Alan; Morley, John E; Rodriguez-Mañas, Leo; Paolisso, Giuseppe; Bayer, Tony; Zeyfang, Andrej; Bourdel-Marchasson, Isabelle; Vischer, Ulrich; Woo, Jean; Chapman, Ian; Dunning, Trisha; Meneilly, Graydon; Rodriguez-Saldana, Joel; Gutierrez Robledo, Luis Miguel; Cukierman-Yaffe, Tali; Gadsby, Roger; Schernthaner, Guntram; Lorig, Kate

    2012-07-01

    Diabetes mellitus is a highly prevalent metabolic condition in ageing societies associated with high levels of morbidity, multiple therapies, and functional deterioration that challenges even the best of health care systems to deliver high-quality, individualized care. Most international clinical guidelines have ignored the often-unique issues of frailty, functional limitation, changes in mental health, and increasing dependency that characterize many aged patients with diabetes. A collaborative Expert Group of the IAGG and EDWPOP and an International Task Force have explored the key issues that affect diabetes in older people using a robust method comprising a Delphi process and an evidence-based review of the literature. Eight domains of interest were initially agreed and discussed: hypoglycemia, therapy, care home diabetes, influence of comorbidities, glucose targets, family/carer perspectives, diabetes education, and patient safety. A set of "consensus" statements was produced in each domain of interest. These form a foundation for future policy development in this area and should influence the clinical behavior and approach of all health professionals engaged in delivering diabetes care to older people. Copyright © 2012 American Medical Directors Association. Published by Elsevier Inc. All rights reserved.

  14. Diagnosis and treatment of peripheral arterial disease in diabetic patients with a foot ulcer. A progress report of the International Working Group on the Diabetic Foot

    NARCIS (Netherlands)

    Schaper, N. C.; Andros, G.; Apelqvist, J.; Bakker, K.; Lammer, J.; Lepantalo, M.; Mills, J. L.; Reekers, J.; Shearman, C. P.; Zierler, R. E.; Hinchliffe, R. J.

    2012-01-01

    The International Working Group on the Diabetic Foot (IWDGF) has produced in 2011 a guideline on the diagnosis and treatment of peripheral arterial disease in patients with diabetes and a foot ulcer. This document, together with a systematic review that provided the background information on

  15. An Internal Audit of Diabetes Care for Type 2 Diabetic Patients in a Public Hospital Diabetes Clinic in Malaysia.

    Science.gov (United States)

    Hieng, Yung Chun

    2017-03-01

    Earlier studies have identified a gap between guidelines and actual clinical diabetes care in Malaysia. We audited the quality of care for patients with type 2 diabetes mellitus (T2DM) attending our diabetes clinic at a public hospital. A structured review of the outpatient clinic cards, prescriptions and laboratory results was conducted for patients attending the diabetes clinic at Sibu Hospital in October and November 2014. For the total of 233 patients who were audited, the levels of fasting blood sugar, blood pressure, body mass index and fasting lipid profile were satisfactory at 99.1%, 99.6%, 92.6% and 99.6% respectively. 79.7% of the subjects had had HbA1c performed at least once over the previous six months. Only 25.8% had annual foot screening, while the eye screening rate was 71.2% and the albuminuria screening rate was 93.6%. For outcome measures, the mean (SD) HbA1c level was 9.2% (1.91%), with 13 patients (6.7%) having HbA1c less than 6.5%; 36.4% of participants achieved BP < 130/80 mmHg; and 69.4% had LDL < 2.6 mmol/L. The majority of the patients were overweight or obese (91.4%). Overall, the performance of diabetic care processes at our hospital was satisfactory, except for foot examination. The glycaemic and weight control among the subjects were suboptimal and warrant an optimised and comprehensive approach on the part of the management.

  16. World Federation for Medical Education Policy on international recognition of medical schools' programme.

    Science.gov (United States)

    Karle, Hans

    2008-12-01

    The increasing globalisation of medicine, as manifested in the migration rate of medical doctors and in the growth of cross-border education providers, has inflicted a wave of quality assurance efforts in medical education, and underlined the need for definition of standards and for introduction of effective and transparent accreditation systems. In 2004, reflecting the importance of the interface between medical education and the healthcare delivery sector, a World Health Organization (WHO)/World Federation for Medical Education (WFME) Strategic Partnership to improve medical education was formed. In 2005, the partnership published Guidelines for Accreditation of Basic Medical Education. The WHO/WFME Guidelines recommend the establishment of proper accreditation systems that are effective, independent, transparent and based on medical education-specific criteria. An important prerequisite for this development was the WFME Global Standards programme, initiated in 1997 and widely endorsed. The standards are now being used in all 6 WHO/WFME regions as a basis for quality improvement of medical education throughout its continuum and as a template for national and regional accreditation standards. Promotion of national accreditation systems will have a pivotal influence on future international appraisal of medical education. Information about accreditation status - the agencies involved and the criteria and procedure used - will be an essential component of new Global Directories of Health Professions Educational Institutions. According to an agreement between the WHO and the University of Copenhagen (UC), these Directories (the Avicenna Directories) will be developed and published by the UC with the assistance of the WFME, starting with renewal of the WHO World Directory of Medical Schools, and sequentially expanding to cover educational institutions for other health professions. The Directories will be a foundation for international meta-recognition ("accrediting the

  17. 11th International Federation of Automatic Control (IFAC) Workshop on Time-Delay Systems

    CERN Document Server

    Fridman, Emilia; Sename, Olivier; Dugard, Luc

    2016-01-01

    This book mostly results from a selection of papers presented during the 11th IFAC (International Federation of Automatic Control) Workshop on Time-Delay Systems, which took place in Grenoble, France, February 4 - 6, 2013.  During this event, 37 papers were presented. Taking into account the reviewers' evaluation and the papers' presentation the best papers have been selected and collected into the present volume. The authors of 13 selected papers were invited to participate to this book and provided a more detailed and improved version of the conference paper. To enrich the book, three more chapters have been included from specialists on time-delay systems who presented their work during the 52nd IEEE Conference on Decision and Control, which held in December 10 - 13, 2013, at Florence, Italy. The content of the book is divided into four main parts as follows: Modeling, Stability analysis, Stabilization and control, and Input-delay systems. Focusing on various topics of time-delay systems, this book will be...

  18. Internal social responsibility: the perception of the public servants from a federal institution

    International Nuclear Information System (INIS)

    Laranja, Leticia Cruz

    2017-01-01

    The paper aims to analyze the perception of public servants from a federal autarchy regarding its practices, actions and Corporate Social Responsibility programs towards its servants, as well as proposing improvements. Thus, a revision of the existing literature on the evolution of Corporate Social Responsibility was carried out, as well as its applications on the public sector and inside its organizations. The quantitative-descriptive research was performed from a survey using a closed questionnaire developed from the Ethos Indicators focused on workforce. The research results indicated the dominance of a negative perception by the servants regarding Internal Social Responsibility practices in the autarchy, as well as the dominant negative perception from servants without leadership positions and with shorter length of service against the point of view of servants that occupy leadership positions and with longer length of service. The research allowed the identification of practices related to Working Conditions, Working Day and Life Quality as being more relevant, and practices regarding Unions Relations as being the least relevant for servants. In order to improve the perception of the servants on the issues evaluated negatively it is recommended to developed actions and programs related to professional development, employability and retirement, health and safety, working conditions and life quality, and to developed actions aimed at employees without leadership positions and with shorter length of service, whose perceptions were more negative. (author)

  19. Communication received on 10 May 1999 from the Permanent Mission of the Russian Federation to the International Atomic Energy Agency

    International Nuclear Information System (INIS)

    1999-01-01

    The document reproduces the text of a communication received on 10 May 1999 from the Permanent Mission of the Russian Federation to the International Atomic Energy Agency, with regard to the resolution adopted by the 42nd Agency General Conference, entitled 'The safety of radiation sources and the security of radioactive materials' (GC(42)/RES/12), in connection with the war in Yugoslavia

  20. International Federation of Library Associations General Conference, Montreal 1982. Official Opening Statements and Speeches. Plenary Session I and II. Papers.

    Science.gov (United States)

    International Federation of Library Associations, The Hague (Netherlands).

    Official opening statements and papers on networking and the development of information technology which were presented at the 1982 International Federation of Library Associations (IFLA) conference include: (1) opening speeches by Else Granheim (IFLA president) and Kenneth H. Rogers (UNESCO Representative); (2) "The Importance of Networks…

  1. Prevalence and factors associated with diabetes mellitus and impaired fasting glucose level among members of federal police commission residing in Addis Ababa, Ethiopia.

    Science.gov (United States)

    Tesfaye, Tariku; Shikur, Bilal; Shimels, Tariku; Firdu, Naod

    2016-11-28

    The prevalence of diabetes mellitus and factors associated with it, nowadays, are increasing in alarming rates among different occupational groups. Of these occupational groups are Police officers that, often, are exposed to unique life styles and stressful situations which may lead to diabetes mellitus and other cardiovascular diseases. Due to this reason, the present study was conducted to assess the prevalence and factors associated with diabetes mellitus and impaired fasting glucose level among members of federal police commission residing in Addis Ababa, Ethiopia. A cross-sectional study design was conducted from April to May 2015. Multistage and systematic random sampling techniques were employed to select the study participants. The study population was federal police commission members living in Addis Ababa and served for at least a year. The data were collected using structured questionnaire, physical examinations and blood samples, based on the WHO stepwise approach. Data were entered in to SPSS version 20.0 and descriptive statistics and logistics regression were used for analysis. Out of the 1003 eligible subjects, 936 (93.3%) police officers have participated in this study. The prevalence of overall impaired glucose homeostasis (IGH) was 120 (13%) of which 47 (5%) were diabetes and 73 (8%) were impaired fasting glucose. Whereas police rank, history of first degree relative who suffered from diabetes, hypertension and waist hip ratio showed a statistical significance with prevalence of diabetes mellitus, age, family history, hypertension, BMI and waist hip ratio were found to be associated with impaired fasting glucose. The study identified a high prevalence of IGH among the police officers. A priority should be given on preventive strategies of diabetes mellitus, as that of communicable diseases, by Federal Police Commission Health Service Directorate, Federal Ministry of Health and other concerned partners.

  2. A history of diabetes insipidus: paving the road to internal water balance.

    Science.gov (United States)

    Eknoyan, Garabed

    2010-12-01

    Diabetes insipidus is an ancient disease considered under the rubric of diabetes, the Greek descriptive term for polyuria, which was unrecognized even after the sweetness of urine was reported as a characteristic of diabetes mellitus in the 17th century. It would be another century before diabetes insipidus was identified from the insipid rather than saccharine taste of urine in cases of polyuria. After its increased recognition, pathologic observations and experimental studies connected diabetes insipidus to the pituitary gland in the opening decades of the 20th century. Simultaneously, posterior pituitary lobe extracts were shown to be vasoconstrictive (vasopressin) and antidiuretic (antidiuretic hormone). As vasopressin was purified and synthesized and its assay became available, it was shown to be released in response to both osmotic and volume stimuli that are integrated in the hypothalamus, and vasopressin thereby was essential to maintaining internal water balance. The antidiuretic properties of vasopressin to treat the rare cases of diabetes insipidus were of limited clinical utility until its vasoconstrictive effects were resuscitated in the 1970s, with the consequent increasing wider use of vasopressin for the treatment of compromised hemodynamic states. In addition, the discovery of antidiuretic hormone receptor blockers has led to their increasing use in managing hypo-osmolar states. Copyright © 2010 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.

  3. Effectiveness of outreach to patients with diabetes who have fallen out of regular care at a federally qualified health center.

    Science.gov (United States)

    Ramirez-Zohfeld, Vanessa; Jean-Jacques, Muriel; Sanserino, Kate; Buchanan, David; Baker, David W

    2012-08-01

    Re-engaging patients who have fallen out of regular care is a challenge for all primary care practices, but especially for federally qualified health centers (FQHCs). We implemented and evaluated a system of proactive telephone and mail outreach within an FQHC serving a predominantly Latino and Spanish-speaking population for patients with diabetes who had not had a visit to the health center for at least six months. The primary study outcome was the proportion of patients who completed a follow-up visit within three months of the outreach. We also examined patient characteristics associated with completing a follow-up visit. Of 208 patients eligible for outreach, 24% (n = 49) completed a follow-up visit. Thirty-six percent (n = 74) had a disconnected or incorrect phone number, 16% (n = 34) were not reached within three phone call attempts, and 20% (n = 22) of letters mailed were returned to sender. Future efforts to re-engage patients in diabetes care should examine shorter intervals before outreach and other outreach strategies.

  4. Recruitment and retention of participants for an international type 1 diabetes prevention trial

    DEFF Research Database (Denmark)

    Franciscus, Margaret; Nucci, Anita; Bradley, Brenda

    2014-01-01

    BACKGROUND: The Trial to Reduce Insulin Dependent Diabetes Mellitus in the Genetically at Risk (TRIGR) is the first multicenter international type 1 diabetes (T1D) prevention trial to be undertaken. A unique feature of TRIGR has been recruitment of eligible pregnant women and enrollment of newborns...... privacy regulations mid-trial. The majority of participants were recruited from primary care antenatal clinics located near the study centers and from a general hospital or pediatric center that was affiliated with a TRIGR Study center. Internet and magazine advertisements were found to be useful...

  5. Internal pudendal artery from type 2 diabetic female rats demonstrate elevated endothelin-1-mediated constriction.

    Science.gov (United States)

    Allahdadi, Kyan J; Hannan, Johanna L; Ergul, Adviye; Tostes, Rita C; Webb, R Clinton

    2011-09-01

    Diabetes is a risk factor for female sexual dysfunction (FSD). FSD has several etiologies, including a vasculogenic component that could be exacerbated in diabetes. The internal pudendal artery supplies blood to the vagina and clitoris and diabetes-associated functional abnormalities in this vascular bed may contribute to FSD. The Goto-Kakizaki (GK) rat is a non-obese model of type 2 diabetes with elevated endothelin-1 (ET-1) activity. We hypothesize that female GK rats have diminished sexual responses and that the internal pudendal arteries demonstrate increased ET-1 constrictor sensitivity. Female Wistar and GK rats were used. Apomorphine (APO)-mediated genital vasocongestive arousal (GVA) was measured. Functional contraction (ET-1 and phenylephrine) and relaxation (acetylcholine, ACh) in the presence or absence of the ETA receptor antagonist (ETA R; atrasentan) or Rho-kinase inhibitor (Y-27632) were assessed in the internal pudendal and mesenteric arteries. Protein expression of ET-1 and RhoA/Rho-kinase signaling pathway was determined in the internal pudendal and mesenteric arteries. APO-mediated GVAs; contraction and relaxation of internal pudendal and mesenteric arteries; ET-1/RhoA/Rho-kinase protein expression. GK rats demonstrated no APO-induced GVAs. Internal pudendal arteries, but not mesenteric arteries, from GK rats exhibited greater contractile sensitivity to ET-1 compared with Wistar arteries. ETA R blockade reduced ET-1-mediated constriction in GK internal pudendal and mesenteric arteries. Rho-kinase inhibition reduced ET-1-mediated constriction of GK internal pudendal but not mesenteric arteries; however, it had no effect on arteries from Wistar rats. RhoA protein expression was elevated in GK internal pudendal arteries. At the highest concentrations, ACh-mediated relaxation was greater in the GK internal pudendal artery; however, no difference was observed in the mesenteric artery. Female GK rats demonstrate decreased sexual responses that may be

  6. Consideraciones sobre el programa de detección de diabetes mellitus en población mexicana: el caso del Distrito Federal Analysis of the diabetes mellitus screening program in the Federal District, Mexico

    Directory of Open Access Journals (Sweden)

    Maria Guadalupe Alvear-Galindo

    2010-02-01

    Full Text Available Desde la salud pública, los programas de detección para diabetes mellitus tipo 2 son un recurso para su vigilancia. La Secretaría de Salud Nacional implementó como estrategia de tamizaje el Programa de Acción Diabetes Mellitus (PADM-2, el cual se basa en dos pruebas secuenciales: Cuestionario de Factores de Riesgo y medición de glucemia capilar. En este trabajo, se exploró la capacidad del PADM-2 como estrategia de tamizaje. El estudio se efectuó en el año 2005, participaron 1.562 individuos que asistieron a seis unidades del primer nivel de atención de la Secretaría de Salud del Gobierno del Distrito. Se consideró como el estándar de oro a la glucosa sérica en ayuno. Al valorar las dos pruebas en serie, la sensibilidad fue de 98%, la especificidad de 58,7%, y el valor predictivo positivo de 16,6%. El valor predictivo positivo apunta a que una alta proporción del gasto se destina a detectar falsos positivos, lo cual hace necesario replantearse los criterios utilizados en el PADM-2, de tal manera que se obtenga un mayor beneficio económico y social.From the public health perspective, programs to detect type 2 diabetes mellitus are a prime resource for surveillance of the disease. As a screening strategy, the Mexican Ministry of Health implemented the Diabetes Mellitus Action Program (PADM-2, based on two sequential tests: the Risk Factor Questionnaire and capillary blood glucose test. This study explored the Program's capacity as a screening strategy. The study was carried out in the year 2005, with a sample of 1,562 that attended six primary care units under the Health Secretariat of the Federal District. Fasting serum glucose was defined as the gold standard. When assessing the two tests sequentially, sensitivity was 98%, specificity 58.7%, and positive predictive value 16.6%. The positive predictive values indicates that a high proportion of the expenditure still goes to detecting false-positives, thus requiring reconsideration

  7. Source index A: Federal law, without agreements under international law. As of December 31, 1994

    International Nuclear Information System (INIS)

    1995-01-01

    The Federal Law Catalogue and relevant sources - BGBl. III - is the basis of the source index A, which from 1st January 1966 onwards publishes the sources of laws and statutes announced in the Federal Law Gazette, part I and part II, as well as in the Federal Gazette. The source index A covers the sources of all statutes and amendments since 1st January 1964. Official directives, however, are not always announced in the Federal Law Gazette, or in the promulgation section of the Federal Gazette, but rather in the official journals of the Federal Ministries, and in the announcement section of the Federal Gazette. This also applies to amendments or cancellations of directives first published in the Federal Law Gazette or in the promulgation section of the Federal Gazette. As the latter and the official journals on the ministries are not scanned for the source index A, there is no guarantee as to complete coverage of directives. Subject scope 75 covers acts and directives relating to mining, nuclear energy, electricity, gas and power supply. (orig.) [de

  8. Brief screening tool for disordered eating in diabetes: internal consistency and external validity in a contemporary sample of pediatric patients with type 1 diabetes.

    Science.gov (United States)

    Markowitz, Jessica T; Butler, Deborah A; Volkening, Lisa K; Antisdel, Jeanne E; Anderson, Barbara J; Laffel, Lori M B

    2010-03-01

    OBJECTIVE To update and validate a diabetes-specific screening tool for disordered eating (the Diabetes Eating Problem Survey [DEPS]) in contemporary youth with type 1 diabetes. RESEARCH DESIGN AND METHODS A total of 112 youth with type 1 diabetes, ages 13-19 years, completed the DEPS. Higher scores on the DEPS indicate more disordered eating behaviors. Youth and their parents also completed additional surveys to examine diabetes-specific family conflict, negative affect related to blood glucose monitoring, youth quality of life, and diabetes burden. Clinicians provided data on height, weight, A1C, and insulin dosing. The DEPS was revised into a shorter, updated measure and validated. RESULTS The revised 16-item DEPS (DEPS-R) displayed excellent internal consistency (Cronbach's alpha = 0.86). Construct validity was demonstrated by positive correlations with zBMI (P = 0.01), A1C (P = 0.001), diabetes-specific family conflict (P diabetes-specific burden (P = 0.0005), and negative correlations with frequency of blood glucose monitoring (P = 0.03) and quality of life (P diabetes-specific self-report measure of disordered eating that can be completed in diabetes. Future studies should focus on using the DEPS-R to identify high-risk populations for prevention of and early intervention for disordered eating behaviors.

  9. Should haemoglobin A be used for the diagnosis of diabetes ...

    African Journals Online (AJOL)

    2011-04-05

    Apr 5, 2011 ... Over the past two decades, type 2 diabetes has emerged as an important medical problem in sub-Saharan Africa. Estimates by the International Diabetes Federation suggest that the largest increase in the prevalence of diabetes is expected to occur in the developing world, including Africa. However, there ...

  10. Relationships of nuclear, architectural and International Federation of Gynecology and Obstetrics grading systems in endometrial cancer.

    Science.gov (United States)

    Toptaş, Tayfun; Peştereli, Elif; Bozkurt, Selen; Erdoğan, Gülgün; Şimşek, Tayup

    2018-03-01

    To examine correlations among nuclear, architectural, and International Federation of Gynecology and Obstetrics (FIGO) grading systems, and their relationships with lymph node (LN) involvement in endometrioid endometrial cancer. Histopathology slides of 135 consecutive patients were reviewed with respect to tumor grade and LN metastasis. Notable nuclear atypia was defined as grade 3 nuclei. FIGO grade was established by raising the architectural grade (AG) by one grade when the tumor was composed of cells with nuclear grade (NG) 3. Correlations between the grading systems were analyzed using Spearman's rank correlation coefficients, and relationships of grading systems with LN involvement were assessed using logistic regression analysis. Correlation analysis revealed a significant and strongly positive relationship between FIGO and architectural grading systems (r=0.885, p=0.001); however, correlations of nuclear grading with the architectural (r=0.535, p=0.165) and FIGO grading systems (r=0.589, p=0.082) were moderate and statistically non-significant. Twenty-five (18.5%) patients had LN metastasis. LN involvement rates differed significantly between tumors with AG 1 and those with AG 2, and tumors with FIGO grade 1 and those with FIGO grade 2. In contrast, although the difference in LN involvement rates failed to reach statistical significance between tumors with NG 1 and those with NG 2, it was significant between NG 2 and NG 3 (p=0.042). Although all three grading systems were associated with LN involvement in univariate analyses, an independent relationship could not be established after adjustment for other confounders in multivariate analysis. Nuclear grading is significantly correlated with neither architectural nor FIGO grading systems. The differences in LN involvement rates in the nuclear grading system reach significance only in the setting of tumor cells with NG 3; however, none of the grading systems was an independent predictor of LN involvement.

  11. COMPARATIVE ANALYSIS OF AVAILABILITY OF THE MEDICINES FOR PRIVILEGED CATEGORIES OF CITIZENS SUFFERING FROM DIABETES MELLITUS IN THE RUSSIAN FEDERATION AND UKRAINE BASED ON THE PHARMACEUTICAL LAW

    Directory of Open Access Journals (Sweden)

    Shapovalov VV (Jr

    2015-04-01

    Full Text Available World Health Organization paid close attention to the timely detection and treatment of diabetes mellitus, since there are more than 382 million people suffering from this disease in the world. Life expectancy of patients with diabetes mellitus is twice as less when compared to their peers who do not suffer health problems and leading a healthy way of life. Based on the statistical data shows that 80% of patients on diabetes live in countries with a low standard of living. The dynamics of diabetes considered not only as a serious disease, but also as an important medical and pharmaceutical, social, economic and criminal legal problem, which is now very important for the Russian Federation, Ukraine and other countries of the world. This is because there is a constant increase in the number of patients suffering from diabetes on, with chronic diseases, the development of micro- and macrovascular complications, which lead to a reduction in life expectancy due to deterioration of its quality. At the same time the availability of the medicines for privileged categories of citizens, who suffer from diabetes mellitus in the Russian Federation and Ukraine depends on many factors. Some of these factors are improving of the management measures and control over the circulation of medicines (drugs; prevention and disease prevention; the use of personalized pharmacotherapy; ensuring the availability of essential medicines for privileged categories of citizens.Therefore, the aim of the work was to study the particularities of legal documents in Ukraine and Russia, aimed at organizing the rules regulating the circulation of the medicines used for diabetes mellitus pharmacotherapy by generalizing forensic and pharmaceutical practices related to the violation of the rights of patients with diabetes. To improve the system of measures of state control over the increasing availability of medicines for citizens of privileged contingent based on the norms of

  12. HIV/AIDS, health and wellbeing study among International Transport Workers' Federation (ITF) seafarer affiliates.

    Science.gov (United States)

    Altaf Chowdhury, Syed Asif; Smith, Jacqueline; Trowsdale, Steve; Leather, Susan

    2016-01-01

    Transport workers generally face a higher-than-average risk of HIV as well as other health challenges. In order to improve understanding of health issues in the maritime sector, including but not limited to HIV/AIDS, and to prepare appropriate responses the International Transport Workers' Federation (ITF) conducted a study of the views and needs of those affiliates. The ITF carried out two surveys. The first consisted of a questionnaire sent to all ITF seafarer affiliates to establish their concerns about health issues, including the impact of HIV/AIDS, and to assess the extent and nature of existing trade union programmes. The second consisted of a knowledge, attitude and behaviour survey on health, wellbeing and AIDS among a cross-section of individual members administered through anonymous and confidential questionnaires by maritime affiliates in four countries in different regions and an identical online questionnaire through Survey Monkey. For the first survey, replies were received from 35 unions in 30 countries, including major seafarer supplying countries - India, Indonesia, Myanmar, Philippines, Turkey, Ukraine - and major beneficial ownership countries such as Germany, Italy, Norway, and South Korea. Health issues of concern included HIV and other sexually transmitted infections for over three-quarters of them, and then alcohol use, weight control, and mental health. All said they would welcome ITF support in starting or strengthening a programme on general health and/or HIV. Replies were received to the second survey from 615 individual seafarers. Half to three-quarters said they worried about their weight, lack of exercise and drinking; over half felt depressed sometimes or often. There were serious knowledge gaps in a number of areas, especially HIV transmission and prevention, as well as high levels of stigma towards workmates with HIV. A number of health issues and information gaps remain unaddressed on board and pre-departure. Mental health is

  13. The Effect of Job Characteristic, Welfare and Work Environment to Employee Performance at PT. Federal International Finance Manado

    OpenAIRE

    Walangitan, Mac Donald; Mandey, S. L.; Tulandi, Christy

    2015-01-01

    Job characteristic is the determinant of the fit between person with a particular line of work that explored. Welfare is the remuneration provided by the company based on the company rules. Work environment is physical and non-physical workplaces that have direct effect on employee. The purpose of this study is to determine the influence of job characteristic, welfare and work environment on employee performance at PT. Federal International Finance Manado. The population in the study is 65 e...

  14. Pengaruh Motivasi dan Disiplin Kerja Terhadap Kinerja Karyawan Pada PT Repex Perdana International (License of Federal Express) Medan

    OpenAIRE

    Rusandi, Adiguna Dwi

    2015-01-01

    The purpose of this research is to know and analyze the influence of motivation and work dicipline variables to employees performance of PT Repex Perdana International (License of Federal Express) Medan. This research is quantitative research using the survey method of Causal Associative which looks for the relation between one variable with another variable The population in this research were all courier as many 31 people. The sampling method using a sample that is saturated sampling techni...

  15. Evaluation of the International Association of the Diabetes In Pregnancy Study Group new criteria: gestational diabetes project.

    Science.gov (United States)

    Kong, Jason M; Lim, Ken; Thompson, David M

    2015-04-01

    To examine the diagnostic rates of gestational diabetes (GDM) and maternal/fetal outcomes before and after replacement of the Carpenter and Coustan (C&C) criteria with the International Association Diabetes Pregnancy Study Group (IADPSG) criteria. A retrospective analysis of all pregnancies in 2 separate 6-month cohorts in the province of British Columbia. The first C&C cohort was defined as a 6-month period prior to the introduction of the IADPSG 75 g glucose tolerance test on October 1, 2010. The IADPSG cohort was studied during a 6-month period after the change. There was a significant increase in rates of GDM when using the IADPSG 75 g criteria, from 7.9% (1838 of 23 211) to 9.4% (2104 of 22 397). There were no significant changes in maternal outcomes when using the IADPSG criteria (caesarean section, induction of labour, perineal laceration, pregnancy-induced hypertension, antepartum hemorrhage >20 weeks or postpartum hospital length of stay). The caesarean section rate was not increased according to multivariate analysis (30.9% vs. 29.7%; p=0.073). There were no significant changes in most fetal outcomes when using the IADPSG criteria (mean gestational age at birth, premature birth, meconium, birth trauma, mean birth weight, large for gestational age, small for gestational age, intrauterine growth restriction), but neonatal hypoglycemia was significantly higher (1.6 % vs. 1.3 %; p=0.007). The rates of GDM were higher when using the new IADPSG criteria. Overall, all of the maternal and most of the fetal outcomes were similar. Copyright © 2015 Canadian Diabetes Association. Published by Elsevier Inc. All rights reserved.

  16. RENOPROTECTION IN DIABETES MELLITUS

    African Journals Online (AJOL)

    of Nephrology and the International Diabetes Federation) have put in place programmes that emphasise the importance of early detection of DN. This article focuses on key mechanisms in the pathogenesis of. DN and concentrate on the traditional and novel therapies that prevent overt renal disease in DM. Pathophysiology ...

  17. Internal Variations in Health-care Federalism in Canada and the United States

    Directory of Open Access Journals (Sweden)

    Vandna Bhatia

    2014-12-01

    Full Text Available Federal systems are prone to dividing health benefits inconsistently across subnational jurisdictions. In this article, we examine how federalism intersects with economic and social factors, particularly gender and immigration status, to create structural barriers to accessing and receiving necessary healthcare. Drawing on insights from the historical institutionalist literature and the experiences of immigrant women in the Canadian and American health systems, we find significant subnational variations in access to health services and insurance coverage. Gaps in service – which are filled (if at all by costly, inaccessible private provision – are the product of piecemeal policymaking, as new programs and services are layered onto existing systems which are themselves outdated and anachronistic. Our analysis demonstrates the need to move beyond analyses of federal state architectures to an intersectional approach to better understand the differential negative impact of subnational variations on equity between social groups and their ability to access to basic health services.

  18. Federal Administrative Court, judgement of December 17, 1986 (nuclear power station at international border)

    International Nuclear Information System (INIS)

    Anon.

    1987-01-01

    In its decision of December 17, 1986, the Federal Administrative Court accepted the right of action of Dutch borderers against an atomic licence for a German nuclear power plant. The necessary involvement according to sec. 42 Paragraph 2 of the Administrative Court Procedure Act results from the violation of the third party protection provision in sec. 7 Atomic Energy Act. (WG) [de

  19. Drenagem interna como fator de diferenciação de Latossolos do Distrito Federal The internal drainage as a differentiation factor in Oxisols of Distrito Federal, Brazil

    Directory of Open Access Journals (Sweden)

    Patrícia Maurício Campos

    2010-03-01

    , the water-table oscillation was monitored using 2.5-m depth observation wells, during one year. The studied Oxisols were considered chemically and physically similar. However, they differed as to morphological and mineralogical characterization, with the presence of concretionary horizons and goethite in the LVA. Goethite stability in this soils was influenced by the water-table oscillation. The presence of concretionry horizons in LVA caused an internal drainage deficiency, which resulted in lower saturated hydraulic conductivity and lower variation of the water-table levels. Therefore, LVA soils show lower agricultural potential than LV ones, in Distrito Federal. Oxisols physicohydric characteristics have little influence on soil diagnostic attributes, except for iron oxides mineralogy, which show increased contents of goethite in low internal drainage conditions.

  20. Experience of Internal and External Education Quality Rate: Esg and the Legislation of the Russian Federation

    Directory of Open Access Journals (Sweden)

    Nikanorov Ivan N.

    2017-01-01

    Full Text Available Overview of regulation of internal and external education quality rate has been presented. The development of regulation an independent assessment of higher education in Russia in the context of ESG has been considered. Authors noticed, that instruments of internal and external quality rate interact in Russian legislation insufficiently.

  1. Voluntary league of peoples vs. coercive world federative state (Völkerstaat/Staatenverein of peoples as states: Kant's and Rawls' considerations concerning international relations: Similarities and

    Directory of Open Access Journals (Sweden)

    Stupar Milorad J.

    2004-01-01

    Full Text Available Although similar in some respects, Rawls' and Kant' visions of world order fall apart on the question of sovereignty. Rawls never advocates of an international single state with international authority. Kant, on the other hand, inspired by the project of Enlightenment, as a final form of international sovereignty sees federative state of states as a provider for eternal peace among peoples.

  2. PENERAPAN ALGORITMA BAYESIAN REGULARIZATION BACKPROPAGATION UNTUK MEMPREDIKSI PENYAKIT DIABETES

    OpenAIRE

    S Suwarno; A A Abdillah

    2017-01-01

    Pada tahun 2015, penderita diabetes di Indonesia sebanyak 10 juta jiwa. Banyaknya penderita diabetes ini semakin bertambah dari tahun ke tahun. Berdasarkan data International Diabetes Federation, diperkirakan pada tahun 2040 banyaknya penduduk Indonesia yang terkena penyakit diabates akan meningkat menjadi 16.2 juta jiwa penduduk. Upaya pendeteksian sejak dini penyakit diabetes perlu dilakukan. Hal ini untuk mengurangi komplikasi penyakit pada penderita pada masa yang akan datang. Neural netw...

  3. Penerapan Algoritma Bayesian Regularization Backpropagation Untuk Memprediksi Penyakit Diabetes

    OpenAIRE

    Suwarno, S; Abdillah, A A

    2016-01-01

    Pada tahun 2015, penderita diabetes di Indonesia sebanyak 10 juta jiwa. Banyaknya penderita diabetes ini semakin bertambah dari tahun ke tahun. Berdasarkan data International Diabetes Federation, diperkirakan pada tahun 2040 banyaknya penduduk Indonesia yang terkena penyakit diabates akan meningkat menjadi 16.2 juta jiwa penduduk. Upaya pendeteksian sejak dini penyakit diabetes perlu dilakukan. Hal ini untuk mengurangi komplikasi penyakit pada penderita pada masa yang akan datang. Neural netw...

  4. Analysis of Russian Federation Foreign Policy in the Field of International Information Security

    Directory of Open Access Journals (Sweden)

    Elena S. Zinovieva

    2014-01-01

    Full Text Available Information and communication technologies (ICT play an essential role in the improvement of the quality of life, economic and socio-political of individual countries and humanity in general. However, ICT development is fraught with new challenges and threats to international and national security. Interstate rivalry in the information sphere generates conflicts, an extreme form of which is an information war. Since 1998, the Russian initiative supports the international cooperation on information security at the global and regional level as well as within the framework of the bilateral relations. The article analyzes the characteristics of the global information society, which has a decisive influence on the international security in the information age, as well as international cooperation in this field. The analysis of Russian foreign policy initiatives in the field of international information security is also presented. Today more than 130 countries develop cyber capabilities, both defensive and offensive, that pose serious threats to the international stability. It's difficult to trace the source of information attacks and its consequences can be devastating and cause retaliation, including the use of conventional weapons. In this situation Russian approach, advocating for the development of the rules of conduct of States and demilitarization of information space in order to ensure its safety, seems urgent and relevant with the international situation.

  5. Text of communication of 14 November 2000 received from the Permanent Mission of the Russian Federation to the International Atomic Energy Agency concerning nuclear disarmament

    International Nuclear Information System (INIS)

    2000-01-01

    The Director General has received a communication dated 14 November 2000 from the Permanent Mission of the Russian Federation to the International Atomic Energy Agency concerning nuclear disarmament, attaching a statement by the President of the Russian Federation. The text of the communication and, as requested therein, the text of the President of the Russian Federation, are attached hereto for the information of Member States

  6. Note to the Secretariat from the Permanent Mission of the Czech and Slovak Federal Republic to the International Organizations in Vienna

    International Nuclear Information System (INIS)

    1993-01-01

    The document reproduces the Note received by the Director General from the Permanent Mission of the Czech and Slovak Federal Republic to the International Organizations in Vienna in connection with the dissolution of the CSFR on 31 December 1992

  7. Resource use associated with type 2 diabetes in Asia, Latin America, the Middle East and Africa: results from the International Diabetes Management Practices Study (IDMPS).

    Science.gov (United States)

    Ringborg, A; Cropet, C; Jönsson, B; Gagliardino, J J; Ramachandran, A; Lindgren, P

    2009-07-01

    To estimate diabetes-related resource use and investigate its predictors among individuals with type 2 diabetes in 24 countries in Asia, Latin America, the Middle East and Africa. Cross-sectional observational data on diabetes-related resource use were collected from 15,016 individuals with type 2 diabetes within the second wave of International Diabetes Management Practices Study. Mean (SD) annual quantities were determined and predictors of diabetes-related hospitalisations, inpatient days, emergency room visits and absenteeism were investigated using negative binomial regression. Patients in Asia (n = 4678), Latin America (n = 6090) and the Middle East and Africa (n = 4248) made a mean (SD) of 3.4 (6.9), 5.4 (6.7) and 2.5 (4.4) General Practitioner visits per year. The mean (SD) number of inpatient days amounted to 3.8 (18.1), 2.2 (13.9) and 2.6 (13.5) per year. Results of the regression analysis showed the major influence of diabetes-related complications and inadequate glycaemic control on resource use. The expected annual rate of hospitalisation of patients with macrovascular complications compared with those without was 4.7 times greater in Asia [incidence rate ratio (IRR) = 4.7, 95% CI: 2.8-7.8, n = 2551], 5.4 times greater in Latin America (IRR = 5.4, 95% CI: 3.0-9.8, n = 3228) and 4.4 times greater in the Middle East and Africa (IRR = 4.4, 95% CI: 2.8-6.9, n = 2630). Micro- and macrovascular complications and inadequate glycaemic control are significant predictors of resource use in people with type 2 diabetes of developing countries. This knowledge confirms the health economic importance of early diagnosis of diabetes, education of patients and glycaemic control.

  8. Sharing data for public health research by members of an international online diabetes social network.

    Science.gov (United States)

    Weitzman, Elissa R; Adida, Ben; Kelemen, Skyler; Mandl, Kenneth D

    2011-04-27

    Surveillance and response to diabetes may be accelerated through engaging online diabetes social networks (SNs) in consented research. We tested the willingness of an online diabetes community to share data for public health research by providing members with a privacy-preserving social networking software application for rapid temporal-geographic surveillance of glycemic control. SN-mediated collection of cross-sectional, member-reported data from an international online diabetes SN entered into a software application we made available in a "Facebook-like" environment to enable reporting, charting and optional sharing of recent hemoglobin A1c values through a geographic display. Self-enrollment by 17% (n = 1,136) of n = 6,500 active members representing 32 countries and 50 US states. Data were current with 83.1% of most recent A1c values reported obtained within the past 90 days. Sharing was high with 81.4% of users permitting data donation to the community display. 34.1% of users also displayed their A1cs on their SN profile page. Users selecting the most permissive sharing options had a lower average A1c (6.8%) than users not sharing with the community (7.1%, p = .038). 95% of users permitted re-contact. Unadjusted aggregate A1c reported by US users closely resembled aggregate 2007-2008 NHANES estimates (respectively, 6.9% and 6.9%, p = 0.85). Success within an early adopter community demonstrates that online SNs may comprise efficient platforms for bidirectional communication with and data acquisition from disease populations. Advancing this model for cohort and translational science and for use as a complementary surveillance approach will require understanding of inherent selection and publication (sharing) biases in the data and a technology model that supports autonomy, anonymity and privacy.

  9. Sharing data for public health research by members of an international online diabetes social network.

    Directory of Open Access Journals (Sweden)

    Elissa R Weitzman

    2011-04-01

    Full Text Available Surveillance and response to diabetes may be accelerated through engaging online diabetes social networks (SNs in consented research. We tested the willingness of an online diabetes community to share data for public health research by providing members with a privacy-preserving social networking software application for rapid temporal-geographic surveillance of glycemic control.SN-mediated collection of cross-sectional, member-reported data from an international online diabetes SN entered into a software application we made available in a "Facebook-like" environment to enable reporting, charting and optional sharing of recent hemoglobin A1c values through a geographic display. Self-enrollment by 17% (n = 1,136 of n = 6,500 active members representing 32 countries and 50 US states. Data were current with 83.1% of most recent A1c values reported obtained within the past 90 days. Sharing was high with 81.4% of users permitting data donation to the community display. 34.1% of users also displayed their A1cs on their SN profile page. Users selecting the most permissive sharing options had a lower average A1c (6.8% than users not sharing with the community (7.1%, p = .038. 95% of users permitted re-contact. Unadjusted aggregate A1c reported by US users closely resembled aggregate 2007-2008 NHANES estimates (respectively, 6.9% and 6.9%, p = 0.85.Success within an early adopter community demonstrates that online SNs may comprise efficient platforms for bidirectional communication with and data acquisition from disease populations. Advancing this model for cohort and translational science and for use as a complementary surveillance approach will require understanding of inherent selection and publication (sharing biases in the data and a technology model that supports autonomy, anonymity and privacy.

  10. Reliability of AOFAS diabetic foot questionnaire in Charcot arthropathy: stability, internal consistency, and measurable difference.

    Science.gov (United States)

    Dhawan, Vibhu; Spratt, Kevin F; Pinzur, Michael S; Baumhauer, Judith; Rudicel, Sally; Saltzman, Charles L

    2005-09-01

    The development of Charcot changes is known to be associated with a high rate of recurrent ulceration and amputation. Unfortunately, the effect of Charcot arthropathy on quality of life in diabetic patients has not been systematically studied because of a lack of a disease-specific instrument. The purpose of this study was to develop and test an instrument to evaluate the health-related quality of life of diabetic foot disease. Subjects diagnosed with Charcot arthropathy completed a patient self-administered questionnaire, and clinicians completed an accompanying observational survey. The patient self-administered questionnaire was organized into five general sections: demographics, general health, diabetes-related symptoms, comorbidities, and satisfaction. The scales measured the effect in six health domains: 1) general health, 2) care, 3) worry, 4) sleep, 5) emotion, and 6) physicality. The psychometric properties of the scales were evaluated and the summary scores for the Short-Form Health Survey (SF-36) were compared to published norms for other major medical illnesses. Of the 89 enrolled patients, 57 who completed the questionnaire on enrollment returned a second completed form at 3-month followup. Over the 3-month followup period most of the patients showed an improvement in the Eichenholtz staging. The internal consistency of most was moderate to high and, in general, the scale scores were stable over 3 months. However, several of the scales suffered from low-ceiling or high-floor effects. Patients with Charcot arthropathy had a much lower physical component score on enrollment than the reported norms for other disease conditions, including diabetes. Quality of life represents an important set of outcomes when evaluating the effectiveness of treatment for patients with Charcot arthropathy. This study represents an initial attempt to develop a standardized survey for use with this patient population. Further studies need to be done with larger groups of

  11. The problems of international transport corridors development on the territory of the Russian Federation

    Directory of Open Access Journals (Sweden)

    Rustamzade M.N.

    2017-03-01

    Full Text Available in the transition of the leading countries of the world on an innovative way of development, transport is considered as one of the most important factors of socio-economic growth in Russia. Transport contributes to strengthening the unity of the economic area of the country, improves the interregional and international transport and economic relations, increases the efficient using of natural resources, develops entrepreneurship and international cooperation. However, there is a number of obstacles before implementation of transport and transit potential of Russia. The paper deals with features of international and national transport corridors on the territory of Russia and the key problems of their functioning and possible ways to overcome them.

  12. On International Cooperation and the Fluminense Federal Institute of Education, Science and Technology

    Directory of Open Access Journals (Sweden)

    Maria Inês Albernaz Kury

    2012-10-01

    Full Text Available This article aims to make a reflection about the need for internationalization of our institution and our own as well as an approach to the theme of International Cooperation and its meaning in the current scenario. This is a compilation of some documents and readings related to the themes in question.

  13. Exploring democracy in the Russian Federation: political regime, public opinion and international assistance

    NARCIS (Netherlands)

    Gerrits, A.W.M.

    2010-01-01

    This article discusses three questions: what is the purpose of ‘democratic’ institutions and practices in Russia's authoritarian political system; how do these institutions and practices resonate with Russian public opinion; and how do they relate to the international democracy-promotion effort in

  14. EDGE study in Russian Federation: efficacy and safety of vildagliptine in comparison with other oral antidiabetic agents in patients with type 2 diabetes mellitus

    Directory of Open Access Journals (Sweden)

    G R Galstyan

    2013-06-01

    Full Text Available According to international consensus, metformin is acknowledged as a first-line therapeutic agent for type 2 diabetes mellitus (T2DM. However, in most cases this treatment eventually requires intensification by supplementation with other hypoglycemic medications. The aim of the EDGE study (Effective Diabetes control with vildaGliptin and vildagliptin/mEtformin was to assess the efficacy and safety of vildagliptin in comparison with other oral agents in routine management of patients with T2DM that has been poorly controlled by metformin monotherapy.

  15. Pulmonary tuberculosis among diabetic patients in internal medicine at point g hospital, bamako - mali.

    Science.gov (United States)

    Sidibé, At; Dembélé, M; Diarra, As; Cissé, I; Bocoum, A; Traoré, Ak; Traoré, Ha

    2005-01-01

    Summary The depression of cellular immunity among diabetic patients exposes them to tuberculosis considered as one of the major diseases of immune-depressive people. The purpose of our study was to evaluate the frequency, gravity, treatment and evolution of pulmonary tuberculosis among our patients affected with diabetes. For that purpose, two descriptive retrospective and prospective studies were undertaken from January 1982 to December 1992 in the Internal Medicine (Internal medicine) department of Hospital of Point G, the national hospital. Thus, 54 diabetics patients hospitalised out of 1 365 had tuberculosis at a frequency rate of 3,95%. The average age of our patients was 49 years +/- 12 and the sex ratio was 2,18 in favour of men. The infection was also more frequent in diabetes type 1 (51,9%) then in type 2 (48,1%), and concerned mainly men (68.51%) who were more than 37 years old (57.41%). Clinically, the common signs to both affections were prevalent namely asthenia: 85,2%, anorexia: 53,7%, weight loss: 66,7%, associated to cough: 81,5% and to dyspnea: 29,6%. However, for a third of the patients (22,2%), tuberculosis was discovered during a systematic check up. All the patients had a glycemia higher than 8mmol/l, with extremes up to 8mmol/l and 32mmol/l, 63% of patient had a febricula. The intradermo cutaneous reaction to tuberculosis (IDR) was negative in 44,4%. The bacilloscopy during direct testing or through the liquid obtained by casing was positive in 64,82%. Tubercular lesions were localised at the top: 91,8%, with an equal attack of the two lungs. During the treatment six products were mainly used comprising Rifampicine (R) isoniazid (INH or H), Streptomycine (S), Ethambutol (E), Thiacetazone (T), and Pyrazinamide (Z). Insulin treatment was done on all patients until tuberculosis was cured. The evolution was favourable after 2 to 3 months of treatment for 48 patients (88,88%) among whom 4: (8,33%) fell sick again. Six patients out of 54 died, i

  16. Health promotion through sport: international sport federations' priorities, actions and opportunities.

    Science.gov (United States)

    Mountjoy, Margo; Costa, A; Budgett, R; Dvorak, J; Engebretsen, L; Miller, S; Moran, J; Foster, J; Carr, J

    2018-01-01

    To identify areas of priority and activity for international sportsfederations (IFs) with respect to athlete health and safety, and global health. Results serve to direct the work of the Association of Summer Olympic IF Medical and Scientific Consultative Group, the International Olympic Committee and to influence IFs' planning and priorities. The 28 IFs participating in the Summer Olympic Games (2016) were asked to rank the relative importance of 11 health-related topics and to report their activities or research initiatives on 27 identified topics using an electronic survey. A comparison with a similar survey (2012) was made. The response rate was 100%. In general, the ' fight against doping ' had the highest priority followed by 'image as a safe sport '. The topics with the lowest importance ratings were ' increasing the number of elite athletes ', and ' health of the general population '. Despite ranking ' health of your athletes ,' as a top priority, IFs are not addressing all aspects of athlete health. In comparison with 2012, there was a significant decrease in priority for IFs is ' health of the general population '. Despite the widespread knowledge of the importance of the promotion of physical activity (sport) on global health, the decreasing priority and programming of the IFs on physical activity promotion is concerning. Although IFs have prioritised the protection of the health of elite athletes, there are gaps in programming demonstrating that IFs are missing important areas of athlete health. Improving recreational athlete health programming could also benefit population health as well as improve IF fan base and sport participation. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  17. Double vs single internal thoracic artery harvesting in diabetic patients: role in perioperative infection rate

    Directory of Open Access Journals (Sweden)

    Parolari Alessandro

    2008-06-01

    Full Text Available Abstract Background The aim of this prospective study is to evaluate the role in the onset of surgical site infections of bilateral internal thoracic arteries harvesting in patients with decompensated preoperative glycemia. Methods 81 consecutive patients with uncontrolled diabetes mellitus underwent elective CABG harvesting single or double internal thoracic arteries. Single left ITA was harvested in 41 patients (Group 1, 50.6%, BITAs were harvested in 40 (Group 2, 49.4%. The major clinical end points analyzed in this study were infection rate, type of infection, duration of infection, infection relapse rate and total hospital length of stay. Results Five patients developed sternal SSI in the perioperative period, 2 in group 1 and 3 in group 2 without significant difference. All sternal SSIs were superficial with no sternal dehiscence. The development of infection from the time of surgery took 18.5 ± 2.1 and 7.3 ± 3.0 days for Groups 1 and 2 respectively. The infections were treated with wound irrigation and debridement, and with VAC therapy as well as with antibiotics. The VAC system was removed after a mean of 12.8 ± 5.1 days, when sterilization was achieved. The overall survival estimate at 1 year was 98.7%. Only BMI was a significant predictor of SSI using multivariate stepwise logistic regression analysis (Odds Ratio: 1.34; 95%Conficdence Interval: 1.02–1.83; p value: 0.04. In the model, the use of BITA was not an independent predictor of SSI. Conclusion CABG with bilateral pedicled ITAs grafting could be performed safely even in diabetics with poor preoperative glycaemic control.

  18. Injuries in men's international ice hockey: a 7-year study of the International Ice Hockey Federation Adult World Championship Tournaments and Olympic Winter Games.

    Science.gov (United States)

    Tuominen, Markku; Stuart, Michael J; Aubry, Mark; Kannus, Pekka; Parkkari, Jari

    2015-01-01

    Information on ice hockey injuries at the international level is very limited. The aim of the study was to analyse the incidence, type, mechanism and severity of ice hockey injuries in men's international ice hockey tournaments. All the injuries in men's International Ice Hockey Federation World Championship tournaments over a 7-year period were analysed using a strict definition of injury, standardised reporting strategies and an injury diagnosis made by a team physician. 528 injuries were recorded in games resulting in an injury rate of 14.2 per 1000 player-games (52.1/1000 player-game hours). Additionally, 27 injuries occurred during practice. For WC A-pool Tournaments and Olympic Winter Games (OWG) the injury rate was 16.3/1000 player-games (59.6/1000 player-game hours). Body checking, and stick and puck contact caused 60.7% of the injuries. The most common types of injuries were lacerations, sprains, contusions and fractures. A laceration was the most common facial injury and was typically caused by a stick. The knee was the most frequently injured part of the lower body and the shoulder was the most common site of an upper body injury. Arenas with flexible boards and glass reduced the risk of injury by 29% (IRR 0.71, (95% CI 0.56 to 0.91)). The incidence of injury during international ice hockey competition is relatively high. Arena characteristics, such as flexible boards and glass, appeared to reduce the risk of injury. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  19. Diabetes

    DEFF Research Database (Denmark)

    Damm, Peter; Mathiesen, Elisabeth R

    2015-01-01

    For >30 years, insulin has been the drug of choice for the medical treatment of gestational diabetes mellitus. However, the use of oral hypoglycaemic agents has increased during the past 1–2 decades, so a recent comparison of treatment with glibenclamide, metformin or insulin in women with gestat......For >30 years, insulin has been the drug of choice for the medical treatment of gestational diabetes mellitus. However, the use of oral hypoglycaemic agents has increased during the past 1–2 decades, so a recent comparison of treatment with glibenclamide, metformin or insulin in women...... with gestational diabetes mellitus is highly relevant....

  20. Women and Diabetes

    Medline Plus

    Full Text Available ... Other Government Agencies and Offices National Diabetes Education Program Diabetes Information on MedlinePlus Diabetes and Depression in ... Advisory Committees Regulatory Information Safety Emergency ... News & Events Training & Continuing Education Inspections & Compliance Federal, ...

  1. Women and Diabetes

    Medline Plus

    Full Text Available ... Other Government Agencies and Offices National Diabetes Education Program Diabetes Information on MedlinePlus Diabetes and Depression in ... Advisory Committees Regulatory Information Safety Emergency Preparedness ... & Events Training & Continuing Education Inspections & Compliance Federal, ...

  2. Diabetes

    Science.gov (United States)

    ... including: Blurry vision Excess thirst Fatigue Frequent urination Hunger Weight loss Because type 2 diabetes develops slowly, ... must be authorized in writing by ADAM Health Solutions. About MedlinePlus Site Map FAQs Customer Support Get ...

  3. Diabetes

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — These datasets provide de-identified insurance data for diabetes. The data is provided by three managed care organizations in Allegheny County (Gateway Health Plan,...

  4. Revision of the International Pharmaceutical Federation's Basel Statements on the future of hospital pharmacy: From Basel to Bangkok.

    Science.gov (United States)

    Vermeulen, Lee C; Moles, Rebekah J; Collins, Jack C; Gray, Andy; Sheikh, Abdul Latif; Surugue, Jacqueline; Moss, Robert J; Ivey, Marianne F; Stevenson, James G; Takeda, Yasuo; Ranjit, Eurek; Chaar, Betty; Penm, Jonathan

    2016-07-15

    The processes used to revise the 2008 Basel Statements on the future of hospital pharmacy are summarized, and the revised statements are presented. The process for revising the Basel Statements followed an approach similar to that used during their initial development. The Hospital Pharmacy Section (HPS) of the International Pharmaceutical Federation (FIP) revised the 2008 FIP Basel Statements in four phases, including a survey of hospital pharmacists worldwide, an internal review, online forums, and a face-to-face "World Café" workshop in Bangkok, Thailand. The global survey on the initial Basel Statements included input from 334 respondents from 62 countries. The majority of respondents agreed that most of the initial Basel Statements were acceptable as written and did not require revision. In total, 11 statements were judged by more than 10% of respondents as needing revision or deletion. The FIP HPS executive committee used the survey results to develop 69 initial revised draft statements. After an online discussion with the international hospital pharmacy community, including individuals from 28 countries representing all six World Health Organization regions, a final set of draft statements was prepared for the live discussion involving participants from 20 countries. The final 65 revised Basel Statements were voted on and accepted. Systematic revision of the FIP Basel Statements resulted in an updated reflection of aspirational goals for the future of hospital pharmacy practice. While this revision reflects the development of new goals for hospital pharmacy practice, the core principles of the Basel Statements remain an essential foundation for the discipline. Copyright © 2016 by the American Society of Health-System Pharmacists, Inc. All rights reserved.

  5. Diabetes Mellitus in Peru.

    Science.gov (United States)

    Villena, Jaime E

    2015-01-01

    Peru is an upper medium-income developing country with an increasing prevalence of chronic diseases, including diabetes. To review and describe the epidemiology, drivers, and diabetes care plan in Peru. The medical literature was reviewed based on systematic searching of PubMed, Scielo, and various gray literature from the International Diabetes Federation, World Health Organization, and local Peruvian agencies. In Peru, diabetes affects 7% of the population. Type 2 diabetes accounts for 96.8% of outpatients visits with this condition. Type 1 diabetes has an incidence of 0.4/100,000 per year, and gestational diabetes affects 16% of pregnancies. The prevalence of glucose intolerance is 8.11% and that of impaired fasting glucose 22.4%. The prevalence of overweight, obesity, and metabolic syndrome in adults is 34.7%, 17.5%, and 25%, respectively. Metabolic syndrome prevalence is greater in women and the elderly and at urban and low-altitude locations. Diabetes is the eighth cause of death, the sixth cause of blindness, and the leading cause of end-stage kidney disease and nontraumatic lower limb amputation. In Peru, diabetes accounts for 31.5% of acute myocardial infarctions and 25% of strokes. Infections, diabetic emergencies, and cardiovascular disorders are the main causes for admissions, with a mortality rate Peru that exposes difficult challenges and shortcomings. The national strategy for tackling diabetes includes promotion of healthy lifestyles; training primary care physicians and providing them with evidence-based clinical practice guidelines, safe and effective medications, and tools for monitoring treatment; and, finally, construction of a comprehensive health care network for early referral in order to prevent, detect, and treat diabetic complications. Copyright © 2015 The Author. Published by Elsevier Inc. All rights reserved.

  6. Integrating systematic screening for gender-based violence into sexual and reproductive health services: results of a baseline study by the International Planned Parenthood Federation, Western Hemisphere Region.

    Science.gov (United States)

    Guedes, A; Bott, S; Cuca, Y

    2002-09-01

    Three Latin American affiliates of the International Planned Parenthood Federation, Western Hemisphere Region, Inc. (IPPF/WHR) have begun to integrate gender-based violence screening and services into sexual and reproductive health programs. This paper presents results of a baseline study conducted in the affiliates. Although most staff support integration and many had already begun to address violence in their work, additional sensitization and training, as well as institution-wide changes are needed to provide services effectively and to address needs of women experiencing violence. Copyright 2002 International Federation of Gynecology and Obstetrics

  7. Achievement of metabolic control goals set by the American Diabetes Association and the International Society for Pediatric and Adolescent Diabetes in pediatric patients with type 1 diabetes from Spain.

    Science.gov (United States)

    Enes, Patricia; Martín-Frías, María; Álvarez, Ma Ángeles; Yelmo, Rosa; Alonso, Milagros; Barrio, Raquel

    2015-02-01

    The "T1D Exchange Clinic Registry" of 13.316 pediatric patients with type 1 diabetes (T1D) in U.S. recently revealed that most children have HbA1c values above target levels established by the American Diabetes Association (ADA) and the International Society for Pediatric and Adolescent Diabetes (ISPAD). The aim of this study is to assess the proportion of youngsters with T1D who meet the internationally accepted targets for good metabolic control of diabetes at a single, referral Pediatric Diabetes Center in Spain. Cross-sectional study of 236 children and adolescents with T1D controlled at our Pediatric Diabetes Unit. We analyzed the compliance to metabolic goals set by ADA and ISPAD and the differences between patients treated with continuous subcutaneous insulin infusion and multiple daily injections. SPSS™ version 21.0. Mean age: 12.6 ± 4.6 years old, mean age at diagnosis: 6.1 ± 4.3 years old and mean diabetes duration: 6.4 ± 4.3 years; 47% female. HbA1c average: 6.7 ± 0.7% (49.7 ± 7.6 mmol/mol). The age-specific ADA and ISPAD HbA1c targets were achieved by 93% and 91% of patients, respectively. Among pump users, 97%/97% met ADA/ISPAD HbA1c targets compared to 87%/88% of MDI users (p = 0.04/p = 0.03), without significant differences in the analysis by groups of age. Among participants, 95%, 62%, 95%, 98% and 89% met HDLc, LDLc, triglycerides, BP and BMI targets. Most patients in our children and adolescent cohort of T1D patients correctly achieve metabolic goals established by ADA and ISPAD with low incidence of hypoglycemia. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  8. Impacts of Initial Transformation to a Patient-Centered Medical Home on Diabetes Outcomes in Federally Qualified Health Centers in Florida.

    Science.gov (United States)

    Kinsell, Heidi S; Hall, Allyson G; Harman, Jeffrey S; Tewary, Sweta; Brickman, Andrew

    2017-10-01

    Federally qualified health centers (FQHCs) in Florida see large numbers of vulnerable patients with diabetes. Patient-centered medical home (PCMH) models can lead to improvements in health for patients with chronic conditions and cost savings for providers. Therefore, FQHCs are increasingly moving to PCMH models of care. The study objective was to examine the effects of initial transformation to a level 3 National Committee for Quality Assurance (NCQA) certified PCMH in 2011, on clinical diabetes outcomes among 27 clinic sites from a network of FQHCs in Florida. We used de-identified, longitudinal electronic health record (EHR) data from 2010-2012 and multivariate logistic regression to analyze the effects of initial transformation on the odds of having well-controlled HbA1c, body mass index (BMI), and blood pressure (BP) among vulnerable patients with diabetes. Models controlled for clustering by year, patient, and organizational characteristics. Overall, transformation to a PCMH was associated with 19% greater odds of having well-controlled HbA1c values with no statistically significant impact on BMI or BP. Subanalyses showed transformation had less of an effect on BP for African American patients and HbA1c control for Medicare enrollees but a greater effect on weight control for patients older than 35 years. Transformation to a PCMH in FQHCs appears to improve the health of vulnerable patients with diabetes, with less improvement for subsets of patients. Future research should seek to understand the heterogeneous effects of patient-centered transformation on various subgroups.

  9. Use of the International Pharmaceutical Federation's Basel Statements to Assess and Advance Hospital Pharmacy Practice: A Scoping Review.

    Science.gov (United States)

    Penm, Jonathan; Chaar, Betty; Moles, Rebekah J

    2016-01-01

    The Basel statements of the International Pharmaceutical Federation, which provide the first global, unified vision for the hospital pharmacy profession, have recently been revised. Originally released in 2008, the Basel statements have since been made available in 21 languages, and thus have the potential for great impact around the world. To conduct a scoping review to examine the extent and nature of research activity related to the Basel statements. Google Scholar, PubMed, and International Pharmaceutical Abstracts were searched using the key term "Basel statements" for relevant research articles. From each included study, data were extracted on geographic location, study design, study outcomes, and use of the Basel statements. The search strategy generated 113 results. Further refinement resulted in 14 English-language articles that met the inclusion criteria. Four of these articles focused on adapting the Basel statements to European practice, an initiative of the European Association of Hospital Pharmacists that led to development of the European statements of Hospital Pharmacy. Six studies focused on monitoring hospital pharmacy practice in Uganda, the Pacific island countries, and the Western Pacific Region. These studies provide valuable baseline data to measure and track the development of hospital pharmacy practices in their respective countries and regions. The remaining 4 studies used qualitative methods to explore the barriers to and facilitators of implementation of the Basel statements in South Africa, China, and Australia. The Basel statements have led to multiple initiatives around the world, involving more than 70 countries. The European and Western Pacific regions have been the most active. Current initiatives should be continued to ensure identification and resolution of issues related to sustaining their use over time.

  10. Federal Administrative Court denies the International Union for the Protection of Life the right to file suit

    International Nuclear Information System (INIS)

    Anon.

    1980-01-01

    In its decision of July 16, 1980, the Federal Administrative Court dismissed the appeal lodged by the International Union for the Protection of Life against the dismissal by the Supreme Administrative Court concerning the action to set aside the preliminary decision on the Kruemmel reactor. The Court denied its right to file suit. The amount in ligitation was fixed at 20000 DM. The appelant cannot assert that his rights are being violated. The appelent's commitment to protect life is not hindered in an administrative way by the preliminary decision. Only members of the association could put forward that the basic rights of the individual protected in Art. 2, Sect. 2 of the Basic Law are being endangered. Section 7 (2) of the Atomic Energy Law does not serve to protect the freedom of association, it gives third party protection for associations only in case of property damage. Neither can the right to file suit be derived for the addressee of a decision from Section 4 (2) of the Ordinance concerning the procedure for licensing nuclear installations. (HSCH) [de

  11. Discriminating Between Legitimate and Predatory Open Access Journals: Report from the International Federation for Emergency Medicine Research Committee

    Directory of Open Access Journals (Sweden)

    Bhakti Hansoti

    2016-09-01

    Full Text Available Introduction: Open access (OA medical publishing is growing rapidly. While subscription-based publishing does not charge the author, OA does. This opens the door for “predatory” publishers who take authors’ money but provide no substantial peer review or indexing to truly disseminate research findings. Discriminating between predatory and legitimate OA publishers is difficult. Methods: We searched a number of library indexing databases that were available to us through the University of California, Irvine Libraries for journals in the field of emergency medicine (EM. Using criteria from Jeffrey Beall, University of Colorado librarian and an expert on predatory publishing, and the Research Committee of the International Federation for EM, we categorized EM journals as legitimate or likely predatory. Results: We identified 150 journal titles related to EM from all sources, 55 of which met our criteria for OA (37%, the rest subscription based. Of these 55, 25 (45% were likely to be predatory. We present lists of clearly legitimate OA journals, and, conversely, likely predatory ones. We present criteria a researcher can use to discriminate between the two. We present the indexing profiles of legitimate EM OA journals, to inform the researcher about degree of dissemination of research findings by journal. Conclusion: OA journals are proliferating rapidly. About half in EM are legitimate. The rest take substantial money from unsuspecting, usually junior, researchers and provide no value for true dissemination of findings. Researchers should be educated and aware of scam journals.

  12. Communication received from the Federal Minister for European and International Affairs of Austria with regard to the Austrian proposal on the multilateralization of the nuclear fuel cycle

    International Nuclear Information System (INIS)

    2007-01-01

    The Agency has received a communication dated 10 May 2007 from the Federal Minister for European and International Affairs of the Republic of Austria, attaching a paper on the Multilateralization of the Nuclear Fuel Cycle. As requested in that communication, the paper is herewith circulated for the information of Member States

  13. Communication received from the Resident Representative of the Russian Federation to the IAEA on the establishment, structure and operation of the International Uranium Enrichment Centre

    International Nuclear Information System (INIS)

    2007-01-01

    The Director General has received a communication dated 7 June 2007 from the Resident Representative of the Russian Federation, with an attachment entitled 'Establishment, Structure and Operation of the International Uranium Enrichment Centre'. As requested in that communication, the letter and its attachment are circulated for the information of Member States

  14. [Type 2 diabetes mellitus and obesity: should we treat the obesity or the diabetes?].

    Science.gov (United States)

    García, Santiago Durán; Sanz, Santiago Durán; Sanz, Alejandro Durán

    2013-09-01

    In this article, we review the results that can be expected after significant weight loss in patients with type 2 diabetes mellitus. We provide consensus-based documentation supported by the American Diabetes Association, the European Association for the Study of Diabetes, and the International Diabetes Federation on the importance of physical exercise, metabolic-bariatric surgery, and drug therapy. Lastly, we report the results of studies published in the last few years on glucagon-like peptide-1 analogs and the new family of oral drugs known as gliflozins, specifically studies published on dapagliflozin. Copyright © 2013 Elsevier España, S.L. All rights reserved.

  15. Preparticipation predictors for championship injury and illness: cohort study at the Beijing 2015 International Association of Athletics Federations World Championships.

    Science.gov (United States)

    Timpka, Toomas; Jacobsson, Jenny; Bargoria, Victor; Périard, Julien D; Racinais, Sébastien; Ronsen, Ola; Halje, Karin; Andersson, Christer; Dahlström, Örjan; Spreco, Armin; Edouard, Pascal; Alonso, Juan-Manuel

    2017-02-01

    To determine preparticipation predictors of injury and illness at a major Athletics championship. A cohort study design was used. Before the 2015 International Association of Athletics Federations World Championships in Athletics, all 207 registered national teams were approached about partaking in a study of preparticipation health; 50 teams accepted. The athletes (n=957) in the participating teams were invited to complete a preparticipation health questionnaire (PHQ). New injuries and illnesses that occurred at the championships were prospectively recorded. Logistic regression analyses were performed with simple and multiple models using any in-championship injury and in-championship illness as outcomes. The PHQ was completed by 307 (32.1%) of the invited athletes; 116 athletes (38.3%) reported an injury symptom during the month before the championships, while 40 athletes (13%) reported an illness symptom. 20 (6.5%) of the participating athletes sustained a health problem during the championships. Endurance athletes were almost 10-fold more likely to sustain an in-championship illness than speed/power athletes (OR, 9.88; 95% CI 1.20 to 81.31; p=0.033). Participants reporting a preparticipation gradual-onset injury symptom were three times more likely (OR, 3.09; 95% CI 1.08 to 8.79; p=0.035) and those reporting an illness symptom causing anxiety were fivefold more likely (OR, 5.56; 95% CI 1.34 to 23.15; p=0.018) to sustain an in-championship injury. Analyses of preparticipation predictors of injury and illness at a major Athletics championship suggest that endurance athletes require particular clinical attention. Preparticipation symptoms causing anxiety are interesting predictors for in-championship health problems. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  16. Proceedings from an international consensus meeting on posttransplantation diabetes mellitus: recommendations and future directions

    DEFF Research Database (Denmark)

    Sharif, A.; Hecking, M.; de Vries, A.P.

    2014-01-01

    to other solid organ transplant recipients. Our recommendations include: terminology revision from new-onset diabetes after transplantation to posttransplantation diabetes mellitus (PTDM), exclusion of transient posttransplant hyperglycemia from PTDM diagnosis, expansion of screening strategies......-based and intended to serve as a template for planned guidelines update, based on systematic and graded literature review, on the diagnosis and management of PTDM...

  17. Diabetes Research in Iran: a Scientometric Analysis of Publications Output.

    Science.gov (United States)

    Rasolabadi, Masoud; Khaledi, Shahnaz; Ardalan, Marlin; Kalhor, Marya Maryam; Penjvini, Susan; Gharib, Alireza

    2015-06-01

    In the developing countries, diabetes mellitus as a chronic diseases, have replaced infectious diseases as the main causes of morbidity and mortality. International Diabetes Federation (IDF) recently estimates 382 million people have diabetes globally and more than 34.6 million people in the Middle East Region and this number will increase to 67.9 million by 2035. The aim of this study was to analyze Iran's research performance on diabetes in national and international context. This Scientometric analysis is based on the Iranian publication data in diabetes research retrieved from the Scopus citation database till the end of 2014. The string used to retrieve the data was developed using "diabetes" keyword in title, abstract and keywords, and finally Iran in the affiliation field was our main string. Iran's cumulative publication output in diabetes research consisted of 4425 papers from 1968 to 2014, with an average number of 96.2 papers per year and an annual average growth rate of 25.5%. Iran ranked 25th place with 4425 papers among top 25 countries with a global share of 0.72 %. Average of Iran's publication output was 6.19 citations per paper. The average citation per paper for Iranian publications in diabetes research increased from 1.63 during 1968-1999 to 10.42 for 2014. Although diabetic population of Iran is increasing, number of diabetes research is not remarkable. International Diabetes Federation suggested increased funding for research in diabetes in Iran for cost-effective diabetes prevention and treatment. In addition to universal and comprehensive services for diabetes care and treatment provided by Iranian health care system, Iranian policy makers should invest more on diabetes research.

  18. Protocol between the Russian Federation and the International Atomic Energy Agency Additional to the Agreement between the Union of Soviet Socialist Republics and the International Atomic Energy Agency for the Application of Safeguards in the Union of Soviet Socialist Republics

    International Nuclear Information System (INIS)

    2008-01-01

    The text of the Protocol between the Russian Federation and the International Atomic Energy Agency Additional to the Agreement between the Union of Soviet Socialist Republics and the International Atomic Energy Agency for the Application of Safeguards in the Union of Soviet Socialist Republics is reproduced in this document for the information of all Members. The Board of Governors approved the Protocol on 21 March 2000. It was signed on 22 March 2000 in Vienna. Pursuant to Article 11 of the Additional Protocol, the Protocol entered into force on 16 October 2007, the date on which the Agency received from the Russian Federation written notification that the procedures of the Russian Federation required for entry into force had been met

  19. Protocol between the Russian Federation and the International Atomic Energy Agency Additional to the Agreement between the Union of Soviet Socialist Republics and the International Atomic Energy Agency for the Application of Safeguards in the Union of Soviet Socialist Republics

    International Nuclear Information System (INIS)

    2008-01-01

    The text of the Protocol between the Russian Federation and the International Atomic Energy Agency Additional to the Agreement between the Union of Soviet Socialist Republics and the International Atomic Energy Agency for the Application of Safeguards in the Union of Soviet Socialist Republics is reproduced in this document for the information of all Members. The Board of Governors approved the Protocol on 21 March 2000. It was signed on 22 March 2000 in Vienna. Pursuant to Article 11 of the Additional Protocol, the Protocol entered into force on 16 October 2007, the date on which the Agency received from the Russian Federation written notification that the procedures of the Russian Federation required for entry into force had been met [fr

  20. Protocol between the Russian Federation and the International Atomic Energy Agency Additional to the Agreement between the Union of Soviet Socialist Republics and the International Atomic Energy Agency for the Application of Safeguards in the Union of Soviet Socialist Republics

    International Nuclear Information System (INIS)

    2008-01-01

    The text of the Protocol between the Russian Federation and the International Atomic Energy Agency Additional to the Agreement between the Union of Soviet Socialist Republics and the International Atomic Energy Agency for the Application of Safeguards in the Union of Soviet Socialist Republics is reproduced in this document for the information of all Members. The Board of Governors approved the Protocol on 21 March 2000. It was signed on 22 March 2000 in Vienna. Pursuant to Article 11 of the Additional Protocol, the Protocol entered into force on 16 October 2007, the date on which the Agency received from the Russian Federation written notification that the procedures of the Russian Federation required for entry into force had been met [es

  1. International challenges without borders: a descriptive study of family physicians' educational needs in the field of diabetes.

    Science.gov (United States)

    Murray, Suzanne; Lazure, Patrice; Schroter, Sara; Leuschner, Philipp J; Posel, Peter; Kellner, Thomas; Jenkins, Richard D

    2011-05-11

    The optimal care of persons with diabetes by general practitioners and family physicians (GP/FP) is complex and requires multiple competencies. This is a fairly unrecognized key challenge in the healthcare systems. In some cases, local and national Continuous Professional Development (CPD) initiatives target these challenges; however there have been few international initiatives, possibly because challenges emerging from different studies have not been linked across national boundaries. In this context, the authors have compiled data about gaps and/or barriers inherent to GP/FP care of persons with type 2 diabetes from Austria, Canada, Germany and the United Kingdom. Secondary analyzes of pre-existing studies were conducted to identify challenges in the care of patients with type 2 diabetes as faced by GPs/FPs. Two sources of data were reviewed: unpublished research data from collaborating organizations and articles from a literature search (in English and German). Articles retrieved were scanned by the research team for relevance to the study objectives and to extract existing gaps and barriers. The identified challenges were then categorized along three major axes: (1) phase of the continuum of care {from screening to management}; (2) learning domain {knowledge, skills, attitudes, behavior, context}; and (3) by country/region. Compilation and categorization were performed by qualitative researchers and discrepancies were resolved through discussion until concordance was achieved. Thirteen challenges faced by GPs/FPs in the care for patients with type 2 diabetes were common in at least 3 of the 4 targeted countries/regions. These issues were found across the entire continuum of care and included: pathophysiology of diabetes, diagnostic criteria, treatment targets assessment, drugs' modes of action, decision-making in therapies, treatment guidelines, insulin therapy, adherence, management of complications, lifestyle changes, team integration, bureaucracy and third

  2. International challenges without borders: a descriptive study of family physicians' educational needs in the field of diabetes

    Directory of Open Access Journals (Sweden)

    Posel Peter

    2011-05-01

    Full Text Available Abstract Background The optimal care of persons with diabetes by general practitioners and family physicians (GP/FP is complex and requires multiple competencies. This is a fairly unrecognized key challenge in the healthcare systems. In some cases, local and national Continuous Professional Development (CPD initiatives target these challenges; however there have been few international initiatives, possibly because challenges emerging from different studies have not been linked across national boundaries. In this context, the authors have compiled data about gaps and/or barriers inherent to GP/FP care of persons with type 2 diabetes from Austria, Canada, Germany and the United Kingdom. Methods Secondary analyzes of pre-existing studies were conducted to identify challenges in the care of patients with type 2 diabetes as faced by GPs/FPs. Two sources of data were reviewed: unpublished research data from collaborating organizations and articles from a literature search (in English and German. Articles retrieved were scanned by the research team for relevance to the study objectives and to extract existing gaps and barriers. The identified challenges were then categorized along three major axes: (1 phase of the continuum of care {from screening to management}; (2 learning domain {knowledge, skills, attitudes, behavior, context}; and (3 by country/region. Compilation and categorization were performed by qualitative researchers and discrepancies were resolved through discussion until concordance was achieved. Results and discussion Thirteen challenges faced by GPs/FPs in the care for patients with type 2 diabetes were common in at least 3 of the 4 targeted countries/regions. These issues were found across the entire continuum of care and included: pathophysiology of diabetes, diagnostic criteria, treatment targets assessment, drugs' modes of action, decision-making in therapies, treatment guidelines, insulin therapy, adherence, management of

  3. Diabetes mellitus and associated diseases from Ethiopian ...

    African Journals Online (AJOL)

    Methods: The researcher has carried out a systematic review of research papers published from 1970 to 2013 on DM and associated diseases in Ethiopia. Results and discussion: According to International Diabetes Federation, IDF 2012 report, the prevalence of DM in Ethiopia stands at 3.32 %. However, DM prevalence of ...

  4. Some Relations of Type 2 Diabetes and Metabolic Syndrome to Colorectal Cancer

    Czech Academy of Sciences Publication Activity Database

    Svačina, Š.; Matoulek, M.; Svobodová, S.; Visokai, V.; Lipská, L.; Plavcová, Marie; Zvárová, Jana

    2003-01-01

    Roč. 29, 4 suppl. (2003), s. 359 ISSN 0338-1684. [International Diabetes Federation Congress /18./. 24.08.2003-29.08.2003, Paris] R&D Projects: GA MZd NB6635; GA MŠk LN00B107 Keywords : diabetes type 2 * metabolic syndrome * colorectal cancer Subject RIV: BB - Applied Statistics, Operational Research

  5. Cyclooxygenase 1 (COX1) expression in Type 2 diabetes mellitus: A ...

    African Journals Online (AJOL)

    Sushma Verma

    2015-08-10

    Aug 10, 2015 ... Abstract Background and purpose: The 6th edition of International Diabetes Federation, 2014 shows an estimate of 387 million people with Type 2 diabetes mellitus (T2DM) worldwide, expected to rise to 592 million by 2035. T2DM is a metabolic disorder, one of the reasons being oxidative stress due to ...

  6. Public Participation and the Rights of the Child: Reflection on International Law Standards in the Legal System of the Russian Federation

    Directory of Open Access Journals (Sweden)

    Mariya Riekkinen

    2016-01-01

    Full Text Available This article deals with the much debated issue of children’s public participation from the perspective of legal practices in the Russian Federation. Having emerged at the level of national jurisdictions, the practice of engaging minors in decision-making processes on issues of public significance – or the practice of public participation of children – is stipulated by the UN Committee on the Rights of the Child, based on Article 12 of the UN Convention on the Rights of the Child. Public participation of minors implies that children have clearly defined opportunities to take part in decision-making processes concerning those political and public matters affecting their interests.Albeit limited by the clause “regarding the issues concerning them,” the claims for such participation are dictated by emerging standards of international law. The author has examined the process of devising these standards in Russian public law. Moreover, an analysis of the evolution of academic views on public participation of children in Russian legal scholarship is also included in this article.Relying extensively on the method of legal analysis and the comparative analysis of the conformity of national public law standards with respect to international law, the author proposes several legal amendments to the Federal law “On the Basic Guarantees of the Rights of the Child in the Russian Federation,” which would lead to anchoring more solidly the participatory right of minors in the legal system of the Russian Federation.

  7. Clinical decisions in patients with diabetes and other cardiovascular risk factors. A statement of the Spanish Society of Internal Medicine.

    Science.gov (United States)

    Gómez-Huelgas, R; Pérez-Jiménez, F; Serrano-Ríos, M; González-Santos, P; Román, P; Camafort, M; Conthe, P; García-Alegría, J; Guijarro, R; López-Miranda, J; Tirado-Miranda, R; Valdivielso, P

    2014-05-01

    Although the mortality associated to cardiovascular diseases (CVD) has been reduced in the last decades, CVD remains the main cause of mortality in Spain and they are associated with an important morbidity and a huge economic burden. The increasing prevalence of obesity and diabetes could be slowing down the mortality reduction in Spain. Clinicians have often difficulty making clinical decisions due to the multiple clinical guidelines available. Moreover, in the current context of economic crisis it is critical to promote an efficient use of diagnostic and therapeutic proceedings to ensure the viability of public health care systems. The Spanish Society of Internal Medicine (SEMI) has coordinated a consensus document to answer questions of daily practice with the aim of facilitating physicians' decision-making in the management of diabetes and cardiovascular risk factors from a cost-efficiency point of view. Copyright © 2013 Elsevier España, S.L. All rights reserved.

  8. External and internal accidents in PWR power plants. Comparison of current regulations in Belgium, United States, France, Federal Republic of Germany and United Kingdom

    International Nuclear Information System (INIS)

    Maere, G. de; Roch, M.; Cavaco, A.; Preat, M.

    1986-01-01

    In this report a comparison is made of the rules and practices applied in various countries (Belgium, France, Federal Republic of Germany, United Kingdom and United States of America) in designing PWR plants to resist natural hazards (first part of the report) and hazards associated with human activities (second part). The third part of the report deals with the practices in different countries concerning the protection against accidents of internal origin [fr

  9. Agreements concluded by the Federal Republic of Germany under international law in the field of environmental protection. Source index in the Federal Law Gazette, part II. As of June 1, 1992

    International Nuclear Information System (INIS)

    Lohse, S.

    1992-01-01

    This compilation contains all agreements under international law in the field of environmental protection, the FRG has joined and that have been published and/or announced in the Federal Law Gazette, part II. The summary is of September 15, 1987. The classification is made according to the subjects: waste management law, pollution is made according to the date of treaty/agreement. For easier access, there are a chronological index, an index of the contracting states and an index of the places of contract. In the annex the relevant treaties with the German Democratic Republic are indicated. (orig.) [de

  10. Agreements concluded by the Federal Republic of Germany under international law in the field of environmental protection. Annex: Treaties with the GDR. (Source index in the Federal Law Gazette, part II). (As of September 15, 1987)

    International Nuclear Information System (INIS)

    Lohse, S.

    1987-01-01

    This compilation contains all agreements under international law in the field of environmental protection, the FRG has joined and that have been published and/or announced in the Federal Law Gazette, part II. The summary is of September 15, 1987. The classification is made according to the subjects: waste management law, pollution abatement law, nuclear law and energy and mining law and within these according to the date of treaty/agreement. For easier access, there are a chronological index, an index of the contracting states and an index of the places of contract. In the annex the relevant treaties with the German Democratic Republic are indicated. (orig./HP) [de

  11. Fourfold increase in prevalence of gestational diabetes mellitus after adoption of the new International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria.

    Science.gov (United States)

    Huhn, Evelyn A; Massaro, Nadine; Streckeisen, Simone; Manegold-Brauer, Gwendolin; Schoetzau, Andreas; Schulzke, Sven M; Winzeler, Bettina; Hoesli, Irene; Lapaire, Olav

    2017-04-01

    The aim was to evaluate the influence of the new International Association of Diabetes and Pregnancy Study Groups (IADPSG) guidelines for screening of gestational diabetes mellitus (GDM) on GDM prevalence in a cohort from a Swiss tertiary hospital. This was a retrospective cohort study involving all pregnant women who were screened for GDM between 24 and 28 weeks of gestation. From 2008 until 2010 (period 1), a two-step approach with 1-h 50 g glucose challenge test (GCT) was used, followed by fasting, 1- and 2-h glucose measurements after a 75 g oral glucose tolerance test (OGTT) in case of a positive GCT. From 2010 until 2013 (period 2), all pregnant women were tested with a one-step 75 g OGTT according to new IADPSG guidelines. In both periods, women with risk factors could be screened directly with a 75 g OGTT in early pregnancy. Overall, 647 women were eligible for the study in period 1 and 720 in period 2. The introduction of the IADPSG criteria resulted in an absolute increase of GDM prevalence of 8.5% (3.3% in period 1 to 11.8% in period 2). The adoption of the IADPSG criteria resulted in a considerable increase in GDM diagnosis in our Swiss cohort. Further studies are needed to investigate if the screening is cost effective and if treatment of our additionally diagnosed GDM mothers might improve short-term as well as long-term outcome.

  12. Pathophysiological characteristics and effects of obesity in women with early and late manifestation of gestational diabetes diagnosed by the International Association of Diabetes and Pregnancy Study Groups criteria.

    Science.gov (United States)

    Bozkurt, Latife; Göbl, Christian S; Pfligl, Lisa; Leitner, Karoline; Bancher-Todesca, Dagmar; Luger, Anton; Baumgartner-Parzer, Sabina; Pacini, Giovanni; Kautzky-Willer, Alexandra

    2015-03-01

    Appropriate risk stratification is essential in gestational diabetes (GDM) diagnosis to optimize therapeutic strategies during pregnancy. However, there are sparse data related to the newly recommended International Association of Diabetes and Pregnancy Study Groups criteria and their use in early pregnancy. This study sought to evaluate clinical and pathophysiological characteristics less up to gestational week (GW) 21 in women with early and late GDM onset. This was a prospective study conducted at the Medical University of Vienna. Pregnant women (n = 211) underwent an oral glucose tolerance test at 16 GW (interquartile range, 14-18 wk) with multiple measurements of glucose, insulin, and C-peptide for evaluation of insulin sensitivity and ß-cell function in addition to detailed obstetrical risk assessment. Clinical followups were performed until end of pregnancy. We performed a metabolic characterization of early-onset GDM. Of 81 women, 49 (23%) showed early (GDMEarly ≤ 21 GW) and 32 (15%) later manifestation (GDMLate ≥ 24 GW) whereas 130 (62%) remained normal-glucose-tolerant (NGT). In contrast with GDMLate, GDMEarly were affected by decreased insulin sensitivity (GDMEarly vs NGT, P obesity. However, ß-cell dysfunction was also detectable in GDMLate, indicating defective compensatory mechanisms emerging already in early pregnancy.

  13. Self-Reported Physical Activity Using the International Physical Activity Questionnaire (IPAQ) in Australian Adults with Type 2 Diabetes, with and Without Peripheral Neuropathy.

    Science.gov (United States)

    Nolan, Rebecca C; Raynor, Annette J; Berry, Narelle M; May, Esther J

    2016-12-01

    The aim of this study was to survey the level of self-reported physical activity in people with type 2 diabetes, with and without peripheral neuropathy. A sample of South Australian adults (n=481) 33 to 88 years of age who had type 2 diabetes, including 55 people with peripheral neuropathy, completed the International Physical Activity Questionnaire (IPAQ). Levels of self-reported physical activity were compared between those with and without peripheral neuropathy. People with type 2 diabetes and peripheral neuropathy (median [Mdn]=1433; interquartile range [IQR]=495 to 3390 metabolic equivalent minutes per week [MET-min/wk]) were less physically active than those without peripheral neuropathy (Mdn=2106; IQR=876 to 4380 MET-min/wk) (p=0.04). A total of 49% of people with type 2 diabetes and peripheral neuropathy met physical activity recommendations of 150 minutes of at least moderate activity per week, compared to 57% of people with type 2 diabetes alone. These findings demonstrate that people with type 2 diabetes and peripheral neuropathy reported being significantly less active than people with type 2 diabetes alone. People with type 2 diabetes and peripheral neuropathy need to be encouraged to perform higher levels of physical activity for biologic, physical and psychological benefits. Further studies using objective measures of physical activity are required to support these results. Copyright © 2016 Canadian Diabetes Association. Published by Elsevier Inc. All rights reserved.

  14. Skeletonized left internal thoracic artery is associated with lower rates of mediastinitis in diabetic patients.

    Science.gov (United States)

    Sá, Michel Pompeu Barros de Oliveira; Soares, Evelyn Figueira; Santos, Cecília Andrade; Figueiredo, Omar Jacobina; Lima, Renato Oliveira Albuquerque; Escobar, Rodrigo Renda; Rueda, Fábio Gonçalves de; Ferraz, Paulo Ernando; Lima, Ricardo Carvalho

    2011-01-01

    Mediastinitis is a serious complication of median sternotomy and is associated to significant morbidity and mortality. Diabetes is a feared risk factor for mediastinitis and viewed with caution by cardiovascular surgeons. To identify risk factors for mediastinitis in diabetics undergoing CABG surgery with use of unilateral ITA in the Division of Cardiovascular Surgery of Pronto Socorro Cardiológico de Pernambuco - PROCAPE. Retrospective study of 157 diabetics operated between May 2007 and April 2010. Nine preoperative variables, five intraoperative variables and seven postoperative variables possibly involved in the development of postoperative mediastinitis were evaluated. Univariate and multivariate logistic regression analyses were applied. The incidence of mediastinitis was 7% (n=11), with a lethality rate of 36.1% (n=4). Variables associated with increased risk of mediastinitis were: use of pedicled ITA (OR 8.25, 95% CI 2.03 to 66.10, P=0.016), postoperative renal complications (OR 5.10, 95% CI 1.03 to 25.62, P=0.049) and re-operation (OR 7.45, 95% CI 1.24 to 42.17, P=0.023). In multivariate analysis using backward logistic regression, only one variable remained as independent risk factor: use of pedicled ITA (OR 7.64, 95% CI 1.95 to 61.6, P=0.048), in comparison to skeletonized ITA. We suggest that diabetics should be considered for strategies to minimize risk of infection. In diabetics that undergo unilateral ITA, the problem seems to be related to how ITA is harvested. Diabetics should always be considered for use of skeletonized ITA.

  15. Communication of 22 May 1998 received from the Permanent Mission of the Russian Federation to the International Atomic Energy Agency

    International Nuclear Information System (INIS)

    1998-01-01

    The document reproduces the text of a communication dated 22 May 1998 received at the IAEA from the Permanent Mission of the Russian Federation to the IAEA, including a statement from the Ministry of Foreign Affairs of Russia and a communication for publication, regarding the tests of nuclear weapons conducted by India on 11 May 1998

  16. Communication of 29 May 1998 received from the Permanent Mission of the Russian Federation to the International Atomic Energy Agency

    International Nuclear Information System (INIS)

    1998-01-01

    The document reproduces the text of a communication dated 29 May 1998 received at the IAEA from the Permanent Mission of the Russian Federation to the IAEA, including a statement from the Ministry of Foreign Affairs of Russia regarding the tests of nuclear devices conducted by Pakistan on 28 May 1998

  17. Social support and self-management capabilities in diabetes patients: An international observational study

    NARCIS (Netherlands)

    Koetsenruijter, J.; Eikelenboom, N.; Lieshout, J. van; Vassilev, I.; Lionis, C.; Todorova, E.; Portillo, M.C.; Foss, C.; Gil, M.; Roukova, P.; Angelaki, A.; Mujika, A.; Knutsen, I.R.; Rogers, A.; Wensing, M.

    2016-01-01

    OBJECTIVE: The objective of this study was to explore which aspects of social networks are related to self-management capabilities and if these networks have the potential to reduce the adverse health effects of deprivation. METHODS: In a cross-sectional study we recruited type 2 diabetes patients

  18. Self-Reported Physical Activity Using the International Physical Activity Questionnaire (IPAQ) in Australian Adults with Type 2 Diabetes, with and Without Peripheral Neuropathy

    OpenAIRE

    Nolan, Rebecca C.; Raynor, Annette J.; Berry, Narelle M.; May, Esther J.

    2016-01-01

    Objective: The aim of this study was to survey the level of self-reported physical activity in people with type 2 diabetes, with and without peripheral neuropathy. Methods: A sample of South Australian adults (n=481) aged 33-88 years with type 2 diabetes, including 55 people with peripheral neuropathy, completed the International Physical Activity Questionnaire (IPAQ). Levels of self-reported physical activity were compared between those with and without peripheral neuropathy. Results: People...

  19. International Student Access to U.S. Higher Education since World War II: How NAFSA (Association of International Educators) Has Influenced Federal Policy

    Science.gov (United States)

    Miyokawa, Norifumi

    2009-01-01

    This dissertation is a study of the policy process behind the legislation and regulation governing international student access to U.S. higher education since the immediate aftermath of World War II. The particular research focus of this dissertation is on NAFSA: Association of International Educators (originally established as the National…

  20. PENERAPAN ALGORITMA BAYESIAN REGULARIZATION BACKPROPAGATION UNTUK MEMPREDIKSI PENYAKIT DIABETES

    Directory of Open Access Journals (Sweden)

    S Suwarno

    2017-03-01

    Full Text Available Pada tahun 2015, penderita diabetes di Indonesia sebanyak 10 juta jiwa. Banyaknya penderita diabetes ini semakin bertambah dari tahun ke tahun. Berdasarkan data International Diabetes Federation, diperkirakan pada tahun 2040 banyaknya penduduk Indonesia yang terkena penyakit diabates akan meningkat menjadi 16.2 juta jiwa penduduk. Upaya pendeteksian sejak dini penyakit diabetes perlu dilakukan. Hal ini untuk mengurangi komplikasi penyakit pada penderita pada masa yang akan datang. Neural network merupakan salah satu metode klasifikasi yang dapat digunakan untuk memprediksi penyakit diabetes. Penelitian ini bertujuan membuat sistem prediksi penyakit diabetes. Kinerja diagnostik sistem Jaringan syaraf tiruan dievaluasi menggunakan analisis Receiver Operating Characteristic (ROC untuk mengetahui tingkat accuracy, sensitivity, dan specificity. Hasil evaluasi menunjukkan klasifikasi menggunakan sistem jaringan syaraf tiruan backpropagation masuk ke dalam kriteria good classification. Artinya, hasil klasifikasi ini dapat digunakan untuk membuat sistem prediksi penyakit diabates.As 2015, an estimated 10 million people had diabetes in Indonesia. Trends suggested the rate would continue to rise year by year. According to the latest International Diabetes Federation, people living with diabetes is expected to rise to 16.2 million by 2040.  Early detection of diabetes is needed to reduce number of people living with diabetes. Neural network classification is one method that can be used to predict diabetes. This research aims to make diabetes disease prediction systems. Artificial neural network diagnostic system performance was evaluated using analysis of Receiver Operating Characteristic (ROC to determine the level of accuracy, sensitivity, and specificity. The results of the evaluation showed that the classification system using backpropagation neural network is good. The results of the classification is used to make diabetes disease prediction

  1. Risk factors of diabetes in North Indians with metabolic syndrome.

    Science.gov (United States)

    Pratyush, Daliparthy D; Tiwari, Shalbha; Singh, Saurabh; Singh, Surya K

    2016-01-01

    Metabolic syndrome progresses to diabetes and determinants of this progression like hyperinsulinemia, hypertriglyceridemia and genetic factors have been speculative. The present study was aimed at quantifying the insulin resistance and influence of family history of diabetes in subjects with metabolic syndrome developing prediabetes and diabetes. Consecutive subjects attending the endocrine clinic were evaluated for metabolic syndrome as per definition of International Diabetes Federation, 2005. The family history of diabetes in their first degree relatives was ascertained and Homeostasis model assessment of Insulin resistance (HOMA-IR), Homeostasis model assessment for beta cell function (HOMA-B) and Quantitative insulin sensitivity check index (QUICKI) were calculated in 163 subjects enrolled. HOMA-IR was higher (pmetabolic syndrome+prediabetes or diabetes compared to metabolic syndrome with normal glucose tolerance. HOMA-B was lower and prevalence of prediabetes and diabetes was higher in metabolic syndrome subjects with family history of diabetes than in those without such family history (pmetabolic syndrome having prediabetes and diabetes had more severe insulin resistance than those with metabolic syndrome only. Beta cell dysfunction was remarkable and prevalence of prediabetes was high in metabolic syndrome subjects with family history of diabetes. Both the severity of the insulin resistance and family history of diabetes are therefore proposed to be determinants of diminished Beta cell function leading to diabetes in metabolic syndrome. Copyright © 2016 Diabetes India. Published by Elsevier Ltd. All rights reserved.

  2. Organizational administrative assurance of the movement of staff within the internal affairs bodies of the Russian Federation

    Directory of Open Access Journals (Sweden)

    Galina JURAVLIOVA

    2017-06-01

    Full Text Available The insufficiency of the scientific development of the organization and legal support of the staff rotation process within Internal Affairs bodies has determined the choice of the article topic.

  3. Impact of ethnicity on gestational diabetes identified with the WHO and the modified International Association of Diabetes and Pregnancy Study Groups criteria: a population-based cohort study.

    Science.gov (United States)

    Jenum, Anne K; Mørkrid, Kjersti; Sletner, Line; Vangen, Siri; Vange, Siri; Torper, Johan L; Nakstad, Britt; Voldner, Nanna; Rognerud-Jensen, Odd H; Berntsen, Sveinung; Mosdøl, Annhild; Skrivarhaug, Torild; Vårdal, Mari H; Holme, Ingar; Yajnik, Chittaranjan S; Birkeland, Kåre I

    2012-02-01

    The International Association of Diabetes and Pregnancy Study Groups (IADPSG) recently proposed new criteria for diagnosing gestational diabetes mellitus (GDM). We compared prevalence rates, risk factors, and the effect of ethnicity using the World Health Organization (WHO) and modified IADPSG criteria. This was a population-based cohort study of 823 (74% of eligible) healthy pregnant women, of whom 59% were from ethnic minorities. Universal screening was performed at 28±2 weeks of gestation with the 75 g oral glucose tolerance test (OGTT). Venous plasma glucose (PG) was measured on site. GDM was diagnosed as per the definition of WHO criteria as fasting PG (FPG) ≥7.0 or 2-h PG ≥7.8 mmol/l; and as per the modified IADPSG criteria as FPG ≥5.1 or 2-h PG ≥8.5 mmol/l. OGTT was performed in 759 women. Crude GDM prevalence was 13.0% with WHO (Western Europeans 11%, ethnic minorities 15%, P=0.14) and 31.5% with modified IADPSG criteria (Western Europeans 24%, ethnic minorities 37%, P< 0.001). Using the WHO criteria, ethnic minority origin was an independent predictor (South Asians, odds ratio (OR) 2.24 (95% confidence interval (CI) 1.26-3.97); Middle Easterners, OR 2.13 (1.12-4.08)) after adjustments for age, parity, and prepregnant body mass index (BMI). This increased OR was unapparent after further adjustments for body height (proxy for early life socioeconomic status), education and family history of diabetes. Using the modified IADPSG criteria, prepregnant BMI (1.09 (1.05-1.13)) and ethnic minority origin (South Asians, 2.54 (1.56-4.13)) were independent predictors, while education, body height and family history had little impact. GDM prevalence was overall 2.4-times higher with the modified IADPSG criteria compared with the WHO criteria. The new criteria identified many subjects with a relatively mild increase in FPG, strongly associated with South Asian origin and prepregnant overweight.

  4. Communication from the Permanent Mission of the Russian Federation to the International Atomic Energy Agency regarding guidelines for transfers of nuclear-related dual-use equipment, materials, software and related technology

    International Nuclear Information System (INIS)

    2000-01-01

    The document reproduces the text of the Note Verbale received by the Director General of the IAEA from the Permanent Mission of the Russian Federation to the International Atomic Energy Agency providing information on the export policies and practices of the Government of the Russian Federation with respect to the export of nuclear-related dual-use equipment, materials, software and related technology

  5. Emotional support for diabetes management: an international cross-cultural study.

    Science.gov (United States)

    Kowitt, Sarah D; Urlaub, Diana; Guzman-Corrales, Laura; Mayer, Melissa; Ballesteros, Juana; Graffy, Jonathan; Simmons, David; Cummings, Doyle M; Fisher, Edwin B

    2015-06-01

    The purpose of this study was to explore how emotional support emerged in interactions between peer supporters (PSs) and adults living with type 2 diabetes. Qualitative data were analyzed from 22 semistructured interviews with PSs in 3 settings: low-income Latinos in Chicago, middle-class Caucasians in the United Kingdom, and low-income African American women in North Carolina. Emotional support was defined as expressions of empathy, trust, and caring. Across all sites, emotional support gradually emerged over time, was often combined with informational support, and was conveyed both implicitly (through nonverbal actions connoting emotional acceptance; eg, a walk together without discussion of problems) and explicitly (eg, by reassurance or discussion of stressors). Cross-site differences did appear regarding the strategies to address barriers to diabetes management (eg, PSs in North Carolina and Chicago reported providing support for social stressors) and the role of PSs (eg, PSs in Chicago reported providing directive support). Across different settings and populations, emotional support for diabetes management evolved over time, was often integrated with informational support, and emerged through both implicit and explicit strategies that addressed varied context-specific stressors. © 2015 The Author(s).

  6. 11 June 2012 - Austrian Federal Minister of Labour, Social Affairs and Consumer Protection R. Hundstorfer signing the guest book with Head of International Relations F. Pauss and Ambassador to the UN C. Strohal (CERN-HI-120611334)

    CERN Multimedia

    2012-01-01

    11 June 2012 - Austrian Federal Minister of Labour, Social Affairs and Consumer Protection R. Hundstorfer signing the guest book with Head of International Relations F. Pauss and Ambassador to the UN C. Strohal (CERN-HI-120611334)

  7. His Excellency Mr Deepak Dhital Ambassador Extraordinary and Plenipotentiary Permanent Representative of the Federal Democratic Republic of Nepal to the United Nations Office and other international organisations in Geneva

    CERN Multimedia

    Bennett, Sophia Elizabeth

    2017-01-01

    His Excellency Mr Deepak Dhital Ambassador Extraordinary and Plenipotentiary Permanent Representative of the Federal Democratic Republic of Nepal to the United Nations Office and other international organisations in Geneva

  8. Aerial Photography and Imagery, Oblique, This data set was acquired through a federal grant with Pictometry International. The imagery is either 4" or 9" resolution., Published in 2011, Not Applicable scale, Chippewa County Government.

    Data.gov (United States)

    NSGIC Local Govt | GIS Inventory — Aerial Photography and Imagery, Oblique dataset current as of 2011. This data set was acquired through a federal grant with Pictometry International. The imagery is...

  9. Gas reactor international cooperative program interim report: United States/Federal Republic of Germany nuclear licensing comparison

    Energy Technology Data Exchange (ETDEWEB)

    1978-09-01

    In order to compare US and FRG Nuclear Licensing, a summary description of United States Nuclear Licensing is provided as a basis. This is followed by detailed information on the participants in the Nuclear Licensing process in the Federal Republic of Germany (FRG). FRG licensing procedures are described and the rules and regulations imposed are summarized. The status of gas reactor licensing in both the U.S. and the FRG is outlined and overall conclusions are drawn as to the major licensing differences. An appendix describes the most important technical differences between US and FRG criteria.

  10. Adherence to International Follow-Up Guidelines in Type 2 Diabetes: A Longitudinal Cohort Study in Luxembourg

    Science.gov (United States)

    Renard, Laurence M.; Bocquet, Valery; Vidal-Trecan, Gwenaelle; Lair, Marie-Lise; Blum-Boisgard, Claudine

    2013-01-01

    Introduction Type 2 diabetes is associated with severe micro- and macro-vascular complications. Physicians’ and patients’ adherence to follow-up guidelines permits postponing or reducing these complications. The objectives were to assess the level of adherence to fundamental follow-up guidelines and determine patients’ characteristics associated with this level of adherence in the context of Luxembourg, where no guidelines were implemented. Study population The exhaustive residing population treated for type 2 diabetes in Luxembourg during the 2000-2006 period (N = 21,068). Methods Seven fundamental criteria were extracted from international guidelines (consultation with the treating physician, HbA1c tests, electrocardiogram, retinal, dental, lipid and renal check-ups). The factors associated with the level of adherence to those criteria were identified using a partial proportional odds model. Results In 2006, despite 90% of the patients consulted at least 4 times their treating physician, only 0.6% completed all criteria; 55.0% had no HbA1c test (−8.6 points since 2000) and 31.1% had a renal check-up (+21.6 points). The sex (ORmale: 0.87 [95%CI, 0.83−0.92]), the nationality (ORNonEU: 0.64 [0.52−0.78]), the type of antidiabetic treatment (ORoral: 1.48 [1.35−1.63], ORmixed: 1.35 [1.20−1.52]) and the type of treating physician (ORG-ID: 0.47 [0.42−0.53]) were the main factors associated with the level of adherence in 2006 (3 or more criteria). Conclusion A large percentage of patients were not provided with a systematic annual follow-up between 2000 and 2006. This study highlighted the necessity to promote guidelines in Luxembourg, education for physicians and to launch a national discussion on a disease management program for diabetic patients. PMID:24244637

  11. Patient level cost of diabetes self-management education programmes: an international evaluation.

    Science.gov (United States)

    Doyle, Gerardine; O'Donnell, Shane; Quigley, Etáin; Cullen, Kate; Gibney, Sarah; Levin-Zamir, Diane; Ganahl, Kristin; Müller, Gabriele; Muller, Ingrid; Maindal, Helle Terkildsen; Chang, Wushou Peter; Van Den Broucke, Stephan

    2017-06-04

    The objective of this study was to examine the value of time-driven activity-based costing (TDABC) in understanding the process and costs of delivering diabetes self-management education (DSME) programmes in a multicountry comparative study. Outpatient settings in five European countries (Austria, Denmark, Germany, Ireland, UK) and two countries outside Europe, Taiwan and Israel. Providers of DSME programmes across participating countries (N=16) including healthcare professionals, administrators and patients taking part in DSME programmes. Primary measure: time spent by providers in the delivery of DSME and resources consumed in order to compute programme costs. Secondary measures: self-report measures of behavioural self-management and diabetes disease/health-related outcomes. We found significant variation in costs and the processes of how DSME programmes are provided across and within countries. Variations in costs were driven by a combination of price variances, mix of personnel skill and efficiency variances. Higher cost programmes were not found to have achieved better relative outcomes. The findings highlight the value of TDABC in calculating a patient level cost and potential of the methodology to identify process improvements in guiding the optimal allocation of scarce resources in diabetes care, in particular for DSME that is often underfunded. This study is the first to measure programme costs using estimates of the actual resources used to educate patients about managing their medical condition and is the first study to map such costs to self-reported behavioural and disease outcomes. The results of this study will inform clinicians, managers and policy makers seeking to enhance the delivery of DSME programmes. The findings highlight the benefits of adopting a TDABC approach to understanding the drivers of the cost of DSME programmes in a multicountry study to reveal opportunities to bend the cost curve for DSME. © Article author(s) (or their employer

  12. New £30M funding for british part of international computer grid Powerful international federation of computers moves into the next phase.

    CERN Multimedia

    Reeves, Danielle

    2007-01-01

    "The British arm of an international effort to build a computing Grid powerful enough to analyse data from the Large Hadron Collider (LHC) particle accelerator at CERN has been awarded GBP 30 million new funding, it was announced last week." (1 page)

  13. People’s Republic of China and Federal Republic of Germany in current international relations in Central Asia

    Directory of Open Access Journals (Sweden)

    A V Tsvyk

    2014-12-01

    Full Text Available This article is devoted to the analysis of the current Sino-German relations in the context of world politics and dynamics of international relations as exemplified by the Central Asia region. Basic problems and prospects for cooperation between China and Germany in this region, as well as possible ways of cooperation of the SCO and the EU are under consideration.

  14. [Diabetic foot care. importance of education].

    Science.gov (United States)

    Torreguitart, Maite Valverde

    2011-05-01

    Diabetes is the most prevalent chronic disease at present. It is estimated that approximately 250 million people worldwide have diabetes, representing 5.9% of the adult population. According to a study published recently in Spain, the prevalence of type 2 diabetes varies between 10 and 15%. Cardiovascular complications associated with the disease produce a high social and health costs significantly reducing the quality of life of patients and their families and are the leading cause of death in developed countries. Complications of diabetes with higher economic costs are the "diabetic foot", which consume about 20% of resources devoted to the care of these patients. Each year more than 1 million people worldwide suffer from a leg amputation due to this condition. Between 50% and 70% of non-traumatic amputations occur in patients with diabetes. Most of these amputations are preceded by a foot ulcer The most important factors related to the development of these ulcers are loss of sensation due to neuropathy minor trauma, foot deformity and peripheral vascular disease. According to the International Diabetes Federation, 15% of people with diabetes will develop foot ulcers during their lifetime. Interventions aimed at preventing foot ulcers in patients such as the comprehensive control, education of people with diabetes and their families as well as health professionals, have been shown to reduce lower extremity amputations by 50% and 85%.

  15. A core outcomes set for clinical trials of interventions for young adults with type 1 diabetes: an international, multi-perspective Delphi consensus study.

    Science.gov (United States)

    Byrne, Molly; O'Connell, Anthony; Egan, Aoife M; Dinneen, Sean F; Hynes, Lisa; O'Hara, Mary Clare; Holt, Richard I G; Willaing, Ingrid; Vallis, Michael; Hendrieckx, Christel; Coyne, Imelda

    2017-12-19

    Achieving consensus from a range of relevant stakeholders about an agreed set of core outcomes to be measured and reported as a minimum in clinical trials has the potential to enhance evidence synthesis and make findings more relevant and applicable. Intervention research to improve outcomes for young adults with type 1 diabetes (T1DM) is hampered by inconsistent use of outcome measures. This population frequently struggles to manage their condition and reports suboptimal clinical outcomes. Our aim was to conduct an international, e-Delphi consensus study to identify a core outcome set (COS) that key stakeholders (young adults with T1DM, diabetes health professionals, diabetes researchers and diabetes policy makers) consider as essential outcomes for future intervention research. Using a list of 87 outcomes generated from a published systematic review, we administered two online surveys to a sample of international key stakeholders. Participants in the first survey (survey 1; n = 132) and the second survey (survey 2; n = 81) rated the importance of the outcomes. Survey 2 participants received information on total mean rating for each outcome and a reminder of their personal outcome ratings from Survey 1. Survey 2 results were discussed at a consensus meeting and participants (n = 12: three young adults with T1DM, four diabetes health professionals, four diabetes researchers and one diabetes policy maker) voted on outcomes. Final core outcomes were included provided that 70% of consensus group participants voted for their inclusion. Eight core outcomes were agreed for inclusion in the final COS: measures of diabetes-related stress; diabetes-related quality of life; number of severe hypoglycaemic events; self-management behaviour; number of instances of diabetic ketoacidosis (DKA); objectively measured glycated haemoglobin (HbA 1C ); level of clinic engagement; and perceived level of control over diabetes. This study is the first to identify a COS for

  16. From Soft Power to Economic Diplomacy? A Comparison of the Changing Rationales and Roles of the U. S. and Canadian Federal Governments in International Education. Research & Occasional Paper Series: CSHE.2.15

    Science.gov (United States)

    Trilokekar, Roopa Desai

    2015-01-01

    Through a historical and comparative analysis of international education policy development in Canada and the U.S., this paper will map the similarities and differences in the two countries. It will highlight the contributions and challenges of the government's involvement in international education (IE) in the two federal states and in…

  17. An international, multicenter, observational survey to evaluate diabetes control in subjects using insulin for the treatment of type 1 and type 2 diabetes mellitus in the Czech Republic and Slovak Republic: study protocol for a cross-sectional survey

    Directory of Open Access Journals (Sweden)

    Brož J

    2016-06-01

    Full Text Available Jan Brož,1 Denisa Janickova Zdarska,1 Jana Urbanova,2 Marek Brabec,3 Bohumila Krivska,4 Viera Donicova,5 Radka Stepanova,6 Emil Martinka,7 Milan Kvapil1 1Department of Internal Medicine, Second Faculty of Medicine, 2Center for Research on Diabetes, Metabolism and Nutrition, Second Department of Internal Medicine, Third Faculty of Medicine, Charles University, 3Institute of Computer Science of the ASCR, vvi, 4Sanofi, Prague, Czech Republic; 5Private Department of Diabetology, Internal Medicine and Metabolism, Kosice, Slovak Republic; 6ADDS sro, Brno, Czech Republic; 7National Institute of Endocrinology and Diabetology, Lubochna, Slovak Republic Background: Despite the improvements in insulin therapy, a large number of patients fail to achieve their target glycated hemoglobin (HbA1c levels. Control of diabetes is often unsatisfactory because the patient does not know about the principles of successful insulin therapy (ie, blood glucose self-monitoring, the principles of insulin administration, titration, current dose adjustments, dietary recommendations, and physical activity preventive measures or because these principles are applied incorrectly or insufficiently. Furthermore, the fear of hypoglycemia may lead to maintaining higher than recommended blood glucose levels. Methods/design: This is a noninterventional, international study focusing on a questionnaire survey of diabetes patients (patient-reported outcome treated with insulin for at least 1 year. It is designed so that the data obtained reflect real access of patients to insulin treatment. The primary objective is to show the results of glycemic control of diabetes (HbA1c achieved in diabetes patients treated with at least one dose of insulin. The secondary objective is to monitor the factors potentially affecting these results, which include the frequency and other characteristics of hypoglycemia, the frequency of blood glucose self-monitoring, and the effects produced when the results

  18. Federal Holidays

    Data.gov (United States)

    Office of Personnel Management — Federal law (5 U.S.C. 6103) establishes the following public holidays for Federal employees. Please note that most Federal employees work on a Monday through Friday...

  19. Patients' education, and its impact on care outcomes, resource consumption and working conditions: data from the International Diabetes Management Practices Study (IDMPS).

    Science.gov (United States)

    Gagliardino, J J; Aschner, P; Baik, S H; Chan, J; Chantelot, J M; Ilkova, H; Ramachandran, A

    2012-04-01

    To evaluate the impact of diabetes education provided to patients with type 2 diabetes mellitus (T2DM) in non-controlled studies ("real-world conditions") on quality of care, resource consumption and conditions of employment. This cross-sectional study and longitudinal follow-up describe the data (demographic and socioeconomic profiles, clinical characteristics, treatment of hyperglycaemia and associated cardiovascular risk factors, resource consumption) collected during the second phase (2006) of the International Diabetes Management Practices Study (IDMPS). Patients received diabetes education directly from the practice nurse, dietitian or educator, or were referred to ad hoc group-education programmes; all programmes emphasized healthy lifestyle changes, self-care and active participation in disease control and treatment. Educated vs non-educated T2DM patients (n=5692 in each group), paired by age, gender and diabetes duration, were randomly recruited for the IDMPS by participating primary-care physicians from 27 countries in Eastern Europe, Asia, Latin America and Africa. Outcome measures included clinical (body weight, height, waist circumference, blood pressure, foot evaluation), metabolic (HbA(1c) levels, blood lipid profile) and biochemical control measures. Treatment goals were defined according to American Diabetes Association guidelines. T2DM patients' education significantly improved the percentage of patients achieving target values set by international guidelines. Educated patients increased their insulin use and self-care performance, had a lower rate of chronic complications and a modest increase in cost of care, and probably higher salaries and slightly better productivity. Diabetes education is an efficient tool for improving care outcomes without having a major impact on healthcare costs. Copyright © 2011 Elsevier Masson SAS. All rights reserved.

  20. Criteria for intraventricular conduction disturbances and pre-excitation. World Health Organizational/International Society and Federation for Cardiology Task Force Ad Hoc.

    Science.gov (United States)

    Willems, J L; Robles de Medina, E O; Bernard, R; Coumel, P; Fisch, C; Krikler, D; Mazur, N A; Meijler, F L; Mogensen, L; Moret, P

    1985-06-01

    In an effort to standardize terminology and criteria for clinical electrocardiography, and as a follow-up of its work on definitions of terms related to cardiac rhythm, an Ad Hoc Working Group established by the World Health Organization and the International Society and Federation of Cardiology reviewed criteria for the diagnosis of conduction disturbances and pre-excitation. Recommendations resulting from these discussions are summarized for the diagnosis of complete and incomplete right and left bundle branch block, left anterior and left posterior fascicular block, nonspecific intraventricular block, Wolff-Parkinson-White syndrome and related pre-excitation patterns. Criteria for intraatrial conduction disturbances are also briefly reviewed. The criteria are described in clinical terms. A concise description of the criteria using formal Boolean logic is given in the Appendix. For the incorporation into computer electrocardiographic analysis programs, the limits of some interval measurements may need to be adjusted.

  1. Social support and self-management capabilities in diabetes patients: An international observational study.

    Science.gov (United States)

    Koetsenruijter, Jan; van Eikelenboom, Nathalie; van Lieshout, Jan; Vassilev, Ivo; Lionis, Christos; Todorova, Elka; Portillo, Mari Carmen; Foss, Christina; Serrano Gil, Manuel; Roukova, Poli; Angelaki, Agapi; Mujika, Agurtzane; Knutsen, Ingrid Ruud; Rogers, Anne; Wensing, Michel

    2016-04-01

    The objective of this study was to explore which aspects of social networks are related to self-management capabilities and if these networks have the potential to reduce the adverse health effects of deprivation. In a cross-sectional study we recruited type 2 diabetes patients in six European countries. Data on self-management capabilities was gathered through written questionnaires and data on social networks characteristics and social support through subsequent personal/telephone interviews. We used regression modelling to assess the effect of social support and education on self-management capabilities. In total 1692 respondents completed the questionnaire and the interview. Extensive informational networks, emotional networks, and attendance of community organisations were linked to better self-management capabilities. The association of self-management capabilities with informational support was especially strong in the low education group, whereas the association with emotional support was stronger in the high education group. Some of the social network characteristics showed a positive relation to self-management capabilities. The effect of informational support was strongest in low education populations and may therefore provide a possibility to reduce the adverse impact of low education on self-management capabilities. Self-management support interventions that take informational support in patients' networks into account may be most effective, especially in deprived populations. Copyright © 2015 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.

  2. Features of the Pathogenetic Mechanisms of Regional Blood Flow Disturbances in Diabetic Foot Syndrome (Lliterature Review

    Directory of Open Access Journals (Sweden)

    О.B. Rusak

    2015-09-01

    Full Text Available Diabetes mellitus (DM is recognized as one of the most important noninfectious disease in the world, the prevalence of which became pandemic. In the list of late complications of DM, diabetic foot syndrome is a leader, causing early disability and high mortality. According to the International Diabetes Federation, from 25 to 47 % of hospital admissions of patients with DM is associated with purulent-destructive lesions of the foot as a result of chronic tissue ischemia. This review highlights the main pathophysiological mechanisms of microcirculatory disorders in diabetic foot syndrome, which lead to critical lower limb ischemia.

  3. Incidence and prevalence of diabetes in children aged Fiji, 2001-2012.

    Science.gov (United States)

    Ogle, Graham D; Morrison, Melinda K; Silink, Martin; Taito, Rigamoto S

    2016-05-01

    Determine the incidence and prevalence of diabetes in children Fiji. Data on all new cases from 2001 to 2012 was collected from the three paediatric diabetes services through the International Diabetes Federation Life for a Child Program. There was no formal secondary ascertainment source, however the medical community is small and all known cases are believed to be included. Forty-two children aged Fiji is very low. Furthermore, its occurrence is markedly more frequent in Indo-Fijians than in native Fijians. Type 2 and neonatal diabetes also occur. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  4. Participation in a farmers' market fruit and vegetable prescription program at a federally qualified health center improves hemoglobin A1C in low income uncontrolled diabetics

    Directory of Open Access Journals (Sweden)

    Richard Bryce

    2017-09-01

    Access to a fruit and vegetable prescription program over a 13-week period led to decreased HbA1C concentrations in uncontrolled type 2 diabetic patients living in an urban area of predominately-lower socioeconomic status.

  5. Communication of 29 April 1996 received from the permanent mission of the Russian Federation to the International Atomic Energy Agency regarding guidelines for the export of nuclear material, equipment and technology

    International Nuclear Information System (INIS)

    1996-01-01

    The Director General of the International Atomic Energy Agency has received a note verbale of 29 April 1996 from the Permanent Mission of the Russian Federation providing information on the export policies and practices of the Government of the Russian Federation with respect to nuclear transfers. In light of the request expressed in the note verbale, the text of the note verbale and its attachment is being circulated

  6. 76 FR 78966 - Federal Aviation Administration

    Science.gov (United States)

    2011-12-20

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Approval of Noise Compatibility Program for Kona International Airport at Keahole, Keahole, North Kona, HI AGENCY: Federal Aviation Administration, DOT. ACTION: Notice. SUMMARY: The Federal Aviation Administration (FAA) announces its findings on...

  7. Association of SNP rs9939609 in FTO gene with metabolic syndrome in type 2 diabetic subjects, rectruited from a tertiary care unit of Karachi, Pakistan

    OpenAIRE

    Fawwad, Asher; Siddiqui, Iftikhar Ahmed; Zeeshan, Nimra Fatima; Shahid, Syed Muhammad; Basit, Abdul

    2015-01-01

    Objective: To determine the association of SNP in FTO gene, rs9939609, with Metabolic Syndrome (MS) in type 2 diabetic subjects at a tertiary care unit of Karachi, Pakistan. Methods: We genotyped FTO rs9939609 SNP in 296 patients with type 2 diabetes from the Out Patient Department (OPD) of Baqai Institute of Diabetology and Endocrinology (BIDE). MS was defined on the basis of International Diabetes Federation (IDF) and National Cholesterol Education program (NCEP) criterion. Association betw...

  8. Fiscal Federalism

    Directory of Open Access Journals (Sweden)

    Tatiana Mosteanu

    2007-06-01

    Full Text Available The central budget of a country collects only a fraction of the total fiscal revenues and executes only o fraction of the national public expenditures, the rest of the revenues and expenditures becoming the responsability of subnational governments. The economist Charles Tiebout developed a theoretical model which although makes an imperfect description of the reality, shows that people’s mobility is being influenced by tax rates and the amount of state/local expenditures. Thus, he suggests that the degree of responsibility that can be appointed to the local budgets should subscribe to the tax – benefits ratio, the extend of the positive externalities and the scale economies of public goods. Also, the issue of revenues distribution among communities is being raised, being identified three kinds of grants used by the public authorities: matching grants, block grants and conditional block grants. In the concept of fiscal federalism there can be found a limited analogy between national public finance theory and international public finance theory, with the international taxation as the pivotal element.

  9. Protocol for a randomised blocked design study using telephone and text-messaging to support cardiac patients with diabetes: a cross cultural international collaborative project.

    Science.gov (United States)

    Wu, Chiung-Jung Jo; Sung, Huei-Chuan; Chang, Anne M; Atherton, John; Kostner, Karam; Courtney, Mary; McPhail, Steven M

    2013-10-09

    The prevalence of type 2 diabetes is rising internationally. Patients with diabetes have a higher risk of cardiovascular events accounting for substantial premature morbidity and mortality, and health care expenditure. Given healthcare workforce limitations, there is a need to improve interventions that promote positive self-management behaviours that enable patients to manage their chronic conditions effectively, across different cultural contexts. Previous studies have evaluated the feasibility of including telephone and Short Message Service (SMS) follow up in chronic disease self-management programs, but only for single diseases or in one specific population. Therefore, the aim of this study is to evaluate the feasibility and short-term efficacy of incorporating telephone and text messaging to support the care of patients with diabetes and cardiac disease, in Australia and in Taiwan. A randomised controlled trial design will be used to evaluate a self-management program for people with diabetes and cardiac disease that incorporates the use of simple remote-access communication technologies. A sample size of 180 participants from Australia and Taiwan will be recruited and randomised in a one-to-one ratio to receive either the intervention in addition to usual care (intervention) or usual care alone (control). The intervention will consist of in-hospital education as well as follow up utilising personal telephone calls and SMS reminders. Primary short term outcomes of interest include self-care behaviours and self-efficacy assessed at baseline and four weeks. If the results of this investigation substantiate the feasibility and efficacy of the telephone and SMS intervention for promoting self management among patients with diabetes and cardiac disease in Australia and Taiwan, it will support the external validity of the intervention. It is anticipated that empirical data from this investigation will provide valuable information to inform future international

  10. Do We Need Updated Guidelines on the Use of Insulin Pump Therapy in Type 2 Diabetes? A Review of National and International Practice Guidelines

    Science.gov (United States)

    Cohen, Ohad; Valentine, William

    2016-01-01

    Background: Continuous subcutaneous insulin infusion (CSII) is used less for type 2 than for type 1 diabetes because of inconsistencies in evidence of effectiveness. We reviewed published guidelines on intensive insulin therapy in type 2 diabetes to assess whether updating of guidance is needed with respect to evidence used and recommendations for CSII in diabetes management. Methods: A literature review was performed to identify published national and international guidelines on type 2 diabetes management. Searches were performed using PubMed, Cochrane Library, and Embase databases, and websites of national health care agencies, reimbursement agencies, and professional associations. Searches were limited to articles published in English between 2004 and 2014 and 1666 unique hits were identified, of which 22 were reviewed following screening. Results: Only 6 of the 22 guidelines identified from North and South America, Western Europe, Greece, and Israel provided specific recommendations on intensive insulin therapy and the role of CSII, and only 1 provided information on the grade of evidence supporting recommendations. Quality appraisal based on the AGREE II tool suggested that published guidelines may have limitations in terms of search methodology and evidence grading, and findings were of mixed rigor and clarity. Only 3 guidelines described the population for whom CSII may be appropriate. Conclusions: Guidelines need to improve the evidence base, rigor, clarity, and grading of evidence associated with recommendations on intensive insulin therapy in type 2 diabetes. Future updates may benefit from considering recent evidence on the efficacy of CSII in poorly controlled patients on MDI. PMID:27621141

  11. A case of central diabetes insipidus after ketamine infusion during an external to internal carotid artery bypass.

    Science.gov (United States)

    Gaffar, Sharib; Eskander, Jonathan P; Beakley, Burton D; McClure, Brian P; Amenta, Peter; Pierre, Nakeisha

    2017-02-01

    We report the first teenage case of ketamine-induced transient central diabetes insipidus. The patient was an 18-year-old woman with moyamoya disease undergoing an external carotid to internal carotid bypass and given a low-dose ketamine infusion. After approximately 2 hours in the supine position, with 0.5 Minimum Alveolar Concentration (MAC) of sevoflurane, a propofol infusion at 50 μg/kg/min, a remifentanil infusion at 0.5 μg/kg/min, and a ketamine infusion at a dose of 10 μg/kg/min, this patient had an excessive urine output. Initially, the Foley catheter contained 50 mL of urine. She was given 1500 mL of crystalloid during the case but produced 2700 mL of urine output. Increasing urine output was noted 1 hour into the procedure around the time that the patient experienced a 2-minute Cushing-like response characterized by bradycardia and hypertension. Several I-Stat samples revealed a worsening hypernatremia. The decision was made to check the urine osmolality and treat the patient with 4 μg of desmopressin (DDAVP). Urine output began to slow down to a normal rate of 2 mg/kg/h, as the patient was transferred from the operating room to the computed tomographic (CT) scanning room for a CT and CT angiogram; both were unremarkable. The neurosurgery team waited until the next day to complete the procedure. The procedure was completed successfully and uneventfully the next day without a ketamine infusion as part of the general anesthetic plan. The Naranjo Adverse Drug Reaction score of 4 suggested a possible relationship between the patient's ketamine infusion and subsequent central diabetes insipidus. The 2 previous cases on this topic have suggested that ketamine, as an N-methyl-d-aspartate receptor antagonist, inhibits vasopressin release in the neurohypophysis. Urine output, urine osmolarity, and serum osmolarity should be monitored in patients given ketamine anesthetic; desmopressin should be present to prevent dangerous long-term sequela. Copyright © 2016

  12. 77 FR 10607 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-02-22

    ...-2011-0367] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The...). [[Page 10608

  13. Utilization of International Association of Diabetes and Pregnancy Study Groups criteria vs. a two-step approach to screening for gestational diabetes mellitus in Chinese women with twin pregnancies.

    Science.gov (United States)

    Liu, X; Chen, Y; Zhou, Q; Shi, H; Cheng, W W

    2015-03-01

    To evaluate prevalence and pregnancy outcomes using the International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria and screening protocol vs. a standard two-step screening approach for gestational diabetes mellitus in Chinese twin pregnancies. A retrospective cohort study for pregnancies during 2007-2013 was performed in a tertiary hospital in Shanghai, China. Data were abstracted from the medical records of twin pregnancies delivered at the hospital. During the period 2007-2011, this hospital used a two-step approach with a 50 g screening with a cut-off value of ≥ 7.8 mmol/l followed by a 100 g diagnostic oral glucose tolerance test (OGTT) utilizing Carpenter-Coustan criteria. In 2012-2013, the hospital switched to the IADPSG protocol of universal 75 g OGTT. Among 1461 twin pregnancies, 643 were screened utilizing IADPSG criteria and 818 using the two-step protocol. Gestational diabetes mellitus was diagnosed more frequently in the IADPSG group than in the two-step group [20.4% and 7.0%, respectively; adjusted odds ratio (aOR) = 3.22; 95% confidence interval (CI) = 2.30-4.52]. During the IADPSG period, the incidence of pre-eclampsia was 38% lower in non-gestational diabetes mellitus affected pregnancies compared with the two-step period (aOR = 0.62; 95% CI = 0.44-0.87). We observed no significant differences in most perinatal outcomes between the two groups. Compared with a standard two-step approach to screening and diagnosis, the IADPSG screening method resulted in a three-fold increase in the incidence of gestational diabetes mellitus in twin pregnancies, with a 38% lower risk of pre-eclampsia but no significant difference in most perinatal outcomes in non-gestational diabetes mellitus affected pregnancies. © 2014 The Authors. Diabetic Medicine © 2014 Diabetes UK.

  14. An Epidemiologic Analysis of Diabetes in Colombia.

    Science.gov (United States)

    Vargas-Uricoechea, Hernando; Casas-Figueroa, Luz Ángela

    2015-01-01

    The burden of diabetes is a global problem, wherein the significant growth of diabetes in Colombia reflects a complex pathophysiology and epidemiology found in many other South American nations. The aim of this study was to analyze epidemiologic data from Colombia and the South American region in general to identify certain disease drivers and target them for intervention to curb the increasing prevalence of diabetes. A detailed search was conducted using MEDLINE, SciELO, HINARI, LILACS, IMBIOMED, and Latindex databases, in addition to clinical practice guidelines, books, manuals, and other files containing relevant and verified information on diabetes in Colombia. According to the International Diabetes Federation and the World Health Organization, the prevalence of diabetes in Colombia is 7.1% and 8.5%, respectively. In contrast, a national survey in Colombia shows a prevalence ranging from 1.84% to 11.2%, depending on how the diagnosis is made, the criteria used, and the age range studied. The prevalence exclusively in rural areas ranges from 1.4% to 7.9% and in urban areas from 1% to 46%. The estimated mean overall (direct and indirect) cost attributed to type 2 diabetes is 5.7 billion Colombian pesos (US $2.7 million). Diabetes is the fifth leading cause of death in Colombia with a rate of 15 deaths per 100,000 individuals. Based on a clustering of factors, 4 relevant disease drivers emerge that may account for the epidemiology of diabetes in Colombia: demographic transition, nutritional transition, forced displacement/internal migration and urban development, and promotion of physical activity. Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.

  15. Communication from the Permanent Mission of the Russian Federation to the International Atomic Energy Agency regarding the export of nuclear material and of certain categories of equipment and other material

    International Nuclear Information System (INIS)

    2000-01-01

    The document reproduces the text of a letter received by the Director general of the IAEA from Permanent Mission of the Russian Federation to the International Atomic Energy Agency concerning the export of nuclear material and of certain categories of equipment and other material

  16. 11 July 2012 - Extraordinary and Plenipotentiary Ambassador M. Alemu Getahun, Permanent Representative of the Federal Democratic Republic of Ethiopia to the United Nations Office and other international organisations in Geneva signing the guest book with Head of International relations F. Pauss.

    CERN Multimedia

    Maximilien Brice

    2012-01-01

    11 July 2012 - Extraordinary and Plenipotentiary Ambassador M. Alemu Getahun, Permanent Representative of the Federal Democratic Republic of Ethiopia to the United Nations Office and other international organisations in Geneva signing the guest book with Head of International relations F. Pauss.

  17. [Effect of physical activity strength on the diabetes mellitus prevalence in the elderly under the influence of International Physical Activity Questionnaire].

    Science.gov (United States)

    Jiang, Chao-qiang; Xu, Lin; Lam, Tai-hing; Zhang, Wei-sen; Liu, Bin; Lin, Jie-ming; Yue, Xiao-jun; Jin, Ya-li; Thomas, G Neil

    2009-05-01

    To examine the impact of International Physical Activity Questionnaire (IPAQ) physical activity intensity on to the prevalence of diabetes mellitus among Chinese elderly. A total number of 1996 residents aged 50 or above living in Guangzhou city were recruited from the phase 3 of the Guangzhou Biobank Cohort Study. Information on physical activity and fasting plasma glucose status was derived from standardized interviews and laboratory assays. Among the participants who were classified as physically active (60.0%), moderate active (29.8%) and inactive (10.2%), the prevalence rates of type 2 diabetes mellitus were 9.1%, 12.0% and 14.2%, respectively. After adjustment on age, sex, obesity and other potential confounding factors, data from logistic regression model showed that the odds ratios (95% confidence interval) for diabetes on subjects in physically moderate active and active group were 0.75(0.46-1.26)and 0.60(0.38-0.97) respectively with P for trend as 0.03, when comparing to those physically inactive ones. Promotion of physical activity might have had some effects in reducing the risk of diabetes mellitus among the older adults.

  18. Planejamento das atividades de auditoria interna nas universidades federais brasileiras: apresentação do embasamento normativo = Planning of the internal audit activities in Brazilian federal universities: presentation of the normative bases

    Directory of Open Access Journals (Sweden)

    Orion Augusto Platt Neto

    2008-07-01

    Full Text Available Este artigo apresenta um enfoque normativo sobre o planejamento anual que deve serrealizado nas unidades de auditoria interna, componentes da estrutura administrativadas universidades federais brasileiras. Deste modo, o objetivo do artigo é apresentar asnormas relativas à elaboração e ao acompanhamento da execução do plano anual deatividades de auditoria interna, que devem ser seguidas pelas universidades federais.Trata-se de umapesquisa aplicada, de natureza qualitativa e de caráter exploratório. O âmbito da pesquisaé restrito às instituições dedicadas ao ensino superior, componentes da administraçãoindireta na esfera federal brasileira. Foi utilizada a análise documental da legislação brasileira sobre controle e auditoria interna na administração pública. A pesquisa queembasou o artigo justifica-se, entre outros motivos, como contribuição à literatura daárea, que sofre escassez quanto às referências direcionadas para a auditoria interna nasuniversidades. Como resultados, foram apresentadas as bases normativas mais recentesque regulam as o planejamento das atividades de auditoria interna nas universidadesfederais, bem como a elaboração do Plano Anual de Atividades da Auditoria Interna (PAINT.As ações de auditoria interna nas universidades federais têm sua base normativa derivadada Constituição Federal de 1988, que, nos artigos 70 e 74, trata do sistema de controleinterno do Poder Executivo Federal. A partir disso, o Decreto Presidencial nº 3.591/00definiu atribuições à Controladoria-Geral da União (CGU e à Secretaria Federal de Controle Interno (SFC para a edição de instruções normativas sobre controle e auditoria interna.This paper presents a normative approach about the annual planning that must becarried through by internal audit units that compose the administrative structure of theBrazilian federal universities. This way, the objective of the paper is to present thespecific rules related to the

  19. Evaluation of "care of the foot" as a risk factor for diabetic foot ulceration: the role of internal physicians.

    Science.gov (United States)

    Oguejiofor, O C; Oli, J M; Odenigbo, C U

    2009-03-01

    Several risk factors predispose the diabetic patient to foot ulceration, including "inadequate care of the foot". This risk factor for foot ulceration has not been previously evaluated among Nigeria diabetic patients and is the objective of this study. One hundred and twenty (120) diabetic patients with and without symptoms of peripheral neuropathy receiving care at the medical outpatient department (MOPD) and the diabetic clinic of the Nnamdi Azikiwe University Teaching Hospital Nnewi were recruited consecutively as they presented. They were administered structured questionnaires to assess some variables concerning care of their feet as provided to them by their physicians. Among the 120 diabetic participants, 83 (69.2%) had neuropathic symptoms (the symptomatic participants) while 37 (30.8%) were asymptomatic (the asymptomatic participants). Eighty (80; 96.4%) of the symptomatic vs 36 (97.3%) of the asymptomatic participants had never had their feet examined by their physician. Also, 26 (31.3%) of the symptomatic vs 12 (32.4%) of the asymptomatic participants had never received any form of advice on how to take special care of their feet by their physician, and 26 (31.3%) of the symptomatic vs 6 (16.2%) of the asymptomatic participants walked unshod most times in their immediate surroundings. Physicians do not provide adequate care to the feet of their diabetic patients irrespective of the presence or absence of neuropathic symptoms, making this variable a critical risk factor for diabetic foot ulceration and amputation. Continuing medical education to health care providers emphasizing adequate "care of the foot" of the diabetic patient, will reduce avoidable loss of limbs to diabetes.

  20. Diabetes in North America and the Caribbean: an update.

    Science.gov (United States)

    Yisahak, Samrawit F; Beagley, Jessica; Hambleton, Ian R; Narayan, K M Venkat

    2014-02-01

    The North America and Caribbean (NAC) Region faces a high burden of diabetes. In 2013, the number of children (aged 0-14 years) with type 1 diabetes was 108,600, with 16.7 new cases diagnosed per 100,000 children. Furthermore, there were 36,755,500 individuals with diabetes (mostly type 2 diabetes) in adults (20-79 years), and an additional 44,277,700 individuals had impaired glucose tolerance. The age-adjusted prevalence of diabetes in adults was 9.6%; the second highest among the seven Regions of the International Diabetes Federation. This estimate is expected to grow to 9.9% by 2035. There was some heterogeneity in the estimates within the Region with the age-adjusted prevalence for the USA estimated at 9.2%, 7.9% for Canada, 12.6% for Mexico, and 9.6% for the Caribbean islands. Mortality due to diabetes in the NAC Region is not limited to older age groups, with 37.6% of deaths occurring in people under the age of 60. The economic impact was also enormous, with healthcare expenditure due to diabetes estimated at 263.2 billion USD for 2013 - the highest of all IDF Regions. Diabetes threatens the public health and economies of countries in the NAC Region, and efforts in prevention and management must be intensified in order to surmount this growing problem. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  1. Communication from the Permanent Mission of the Russian Federation to the International Atomic Energy Agency regarding guidelines for transfers of nuclear-related dual-use equipment, materials, software and related technology

    International Nuclear Information System (INIS)

    2001-01-01

    The Director General of the International Atomic Energy Agency has received a Note Verbale from the Permanent Mission of the Russian Federation providing information on the export policies and practices of the Government of the Russian Federation with respect to the export of nuclear-related dual-use equipment, materials, software and related technology. In the light of the wish expressed at the end of the Note Verbale, the text of the Note Verbale is attached. The attachment to the Note Verbale was issued previously as INFCIRC/2541Rev. 4/Part 2

  2. Secondary Prevention of Cardiovascular Disease in Patients With Type 2 Diabetes Mellitus: International Insights From the TECOS Trial (Trial Evaluating Cardiovascular Outcomes With Sitagliptin).

    Science.gov (United States)

    Pagidipati, Neha J; Navar, Ann Marie; Pieper, Karen S; Green, Jennifer B; Bethel, M Angelyn; Armstrong, Paul W; Josse, Robert G; McGuire, Darren K; Lokhnygina, Yuliya; Cornel, Jan H; Halvorsen, Sigrun; Strandberg, Timo E; Delibasi, Tuncay; Holman, Rury R; Peterson, Eric D

    2017-09-26

    Intensive risk factor modification significantly improves outcomes for patients with diabetes mellitus and cardiovascular disease. However, the degree to which secondary prevention treatment goals are achieved in international clinical practice is unknown. Attainment of 5 secondary prevention parameters-aspirin use, lipid control (low-density lipoprotein cholesterol diabetes mellitus and known cardiovascular disease at entry into TECOS (Trial Evaluating Cardiovascular Outcomes With Sitagliptin). Logistic regression was used to evaluate the association between individual and regional factors and secondary prevention achievement at baseline. Cox proportional hazards regression analysis was used to determine the association between baseline secondary prevention achievement and cardiovascular death, myocardial infarction, or stroke. Overall, 29.9% of patients with diabetes mellitus and cardiovascular disease achieved all 5 secondary prevention parameters at baseline, although 71.8% achieved at least 4 parameters. North America had the highest proportion (41.2%), whereas Western Europe, Eastern Europe, and Latin America had proportions of ≈25%. Individually, blood pressure control (57.9%) had the lowest overall attainment, whereas nonsmoking status had the highest (89%). Over a median 3.0 years of follow-up, a higher baseline secondary prevention score was associated with improved outcomes in a step-wise graded relationship (adjusted hazard ratio, 0.60; 95% confidence interval, 0.47-0.77 for those patients achieving all 5 measures versus those achieving ≤2). In an international trial population, significant opportunities exist to improve the quality of cardiovascular secondary prevention care among patients with diabetes mellitus and cardiovascular disease, which in turn could lead to reduced risk of downstream cardiovascular events. URL: http://www.clinicaltrials.gov. Unique identifier: NCT00790205. © 2017 American Heart Association, Inc.

  3. Type 1 diabetes care updates: Tanzania

    Directory of Open Access Journals (Sweden)

    Kandi Catherine Muze

    2015-01-01

    Full Text Available Tanzania is located in east Africa with a population of 45 million. The country′s population is growing at 2.5% annually. The International Diabetes Federation Child Sponsorship Program was launched in Tanzania in 2005. The number of type 1 diabetes mellitus children enrolled in the changing diabetes in children program in Tanzania has augmented from almost below 50 in 2005 to over 1200 in 2014. The country had an overall trend of HbA1c value of 14% in 2005 while the same has reduced over the years to 10% in 2012-13. The program has been able to reduce the proportion of patients with HbA1c values of 11-14%; from 71.9% in 2008 to 49.8% in 2012-13. The challenges, which CDiC faces are misdiagnosis, low public awareness, and stigma especially in the reproductive age/adolescent groups.

  4. Federal Investment

    Science.gov (United States)

    Campbell, Sheila; Tawil, Natalie

    2013-01-01

    The federal government pays for a wide range of goods and services that are expected to be useful some years in the future. Those purchases, called investment, fall into three categories: physical capital, research and development (R&D), and education and training. There are several economic rationales for federal investment. It can provide…

  5. 76 FR 34130 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-06-10

    ...-0144] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  6. 77 FR 74271 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-12-13

    ...-0349] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  7. 76 FR 25769 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-05-05

    ...-0103] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  8. 76 FR 71112 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-11-16

    ...-0300] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  9. 76 FR 9862 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-02-22

    ...-0025] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  10. 78 FR 79062 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-12-27

    ...-0193] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  11. 78 FR 22599 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-04-16

    ...-0016] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  12. 78 FR 16032 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-03-13

    ...-0014] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  13. 78 FR 78479 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-12-26

    ...-0192] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... insulin- treated diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate... individual assessment of drivers with diabetes mellitus, and be consistent with the criteria described in...

  14. 77 FR 5870 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-02-06

    ...-0381] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM...

  15. 77 FR 46149 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-08-02

    ...-0164] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  16. 78 FR 38439 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-06-26

    ...-0020] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  17. 77 FR 64181 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-10-18

    ...-0283] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  18. 76 FR 66120 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-10-25

    ...-0278] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  19. 77 FR 70530 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-11-26

    ...-0348] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice of applications for exemption from the diabetes... revision must provide for individual assessment of drivers with diabetes mellitus, and be consistent with...

  20. 78 FR 38435 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-06-26

    ...-0181] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  1. 77 FR 36333 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-06-18

    ...-0162] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  2. 78 FR 20381 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-04-04

    ...-0015] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  3. 77 FR 533 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-01-05

    ...-0367] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM...

  4. 78 FR 26419 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-05-06

    ...-0018] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  5. 76 FR 64165 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-10-17

    ...-0277] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM...

  6. 77 FR 65931 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-10-31

    ...-0347] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... diabetes mellitus requirement; request for comments. SUMMARY: FMCSA announces receipt of applications from 12 individuals for exemption from the prohibition against persons with insulin-treated diabetes...

  7. 78 FR 7852 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-02-04

    ...-0011] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  8. 76 FR 9854 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-02-22

    ...-0011] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  9. 78 FR 1923 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-01-09

    ...-0350] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  10. 78 FR 14406 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-03-05

    ...-0013] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice of applications for exemption from the diabetes... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM...

  11. 77 FR 56258 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-09-12

    ...-0219] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  12. 77 FR 40941 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-07-11

    ...-0163] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  13. 76 FR 61140 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-10-03

    ...-0194] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice of applications for exemption from the diabetes... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM...

  14. 77 FR 52384 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-08-29

    ...-0218] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... from the diabetes mellitus requirement; request for comments. SUMMARY: FMCSA announces receipt of... diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce. If granted, the...

  15. 78 FR 1927 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-01-09

    ...-0351] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  16. 77 FR 10612 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-02-22

    ...-0382] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  17. Disturbances of energy metabolism in the internal organs in traumatic cranial injury on the background of diabetes

    Directory of Open Access Journals (Sweden)

    V. M. Meretskyі

    2013-10-01

    Full Text Available Traumatic cranial injury is one of the leading reasons in the statistics of mortality. Modern ideas about the pathogenesis of traumatic brain injury based on the allocation of primary and secondary factors of brain damage. One of the main causes of secondary brain injury is hypoxia – insufficient provision with oxygen. Changes in oxygen balance lead to activation of oxidative stress, disturbances of mitochondria membranes and their death, and progression of energy metabolism imbalance caused by trauma. Millions of people worldwide suffer from diabetes mellitus. One of the factors that influences the development of complications of diabetes, is an accumulation of highly toxic peroxide compounds that intensify the processes of destabilization of cell membranes. Further research of peculiarities of oxidative stress and energy metabolism imbalance in diabetes associated with trauma will provide the basis for therapeutic directions to increase treatment options and improve patient health and well-being. Therefore, the purpose of this work is to study the effect of traumatic cranial injury on the energy supplying processes in the liver and kidneys of rats with streptozotocin diabetes, as well as establishing a link between impaired mitochondrial oxidation and the intensity of oxidative stress. Hundred adult male Wistar rats, weighing 180-220 g, were used in this study. Rats were assigned to one of four groups: (1 control animals (n=10; (2 rats with diabetes (n=10; (3 rats with closed cranial trauma (n=40; (4 animals with cranial trauma on the diabetes background (n=40. To induce diabetes, streptozotocin (“Sigma-Aldrich”,USA was dissolved in citrate buffer (pH 4.5 and a single intra-peritoneal injection (60 mg/kg was given to each animal. The application of the cranial injury was done according to the method developed in our laboratory. The rats were sacrificed under thiopental sodium anesthesia by total bloodletting from the heart. The rats of

  18. Safe and pragmatic use of sodium–glucose co-transporter 2 inhibitors in type 2 diabetes mellitus: South Asian Federation of Endocrine Societies consensus statement

    Directory of Open Access Journals (Sweden)

    Sanjay Kalra

    2017-01-01

    Full Text Available Diabetes prevalence shows a continuous increasing trend in South Asia. Although well-established treatment modalities exist for type 2 diabetes mellitus (T2DM management, they are limited by their side effect profile. Sodium–glucose co-transporter 2 inhibitors (SGLT2i with their novel insulin-independent renal action provide improved glycemic control, supplemented by reduction in weight and blood pressure, and cardiovascular safety. Based on the clinical outcomes with SGLT2i in patients with T2DM, treatment strategies that make a “good clinical sense” are desirable. Considering the peculiar lifestyle, body types, dietary patterns (long duration religious fasts, and the hot climate of the South Asian population, a unanimous decision was taken to design specific, customized guidelines for T2DM treatment strategies in these regions. The panel met for a discussion three times so as to get a consensus for the guidelines, and only unanimous consensus was included. After careful consideration of the quality and strength of the available evidence, the executive summary of this consensus statement was developed based on the American Association of Clinical Endocrinologists/American College of Endocrinology protocol.

  19. Combined circular external fixation and open reduction internal fixation with pro-syndesmotic screws for repair of a diabetic ankle fracture

    Directory of Open Access Journals (Sweden)

    Zacharia Facaros

    2010-10-01

    Full Text Available The surgical management of ankle fractures among the diabetic population is associated with higher complication rates compared to the general population. Efforts toward development of better methods in prevention and treatment are continuously evolving for these injuries. The presence of peripheral neuropathy and the possible development of Charcot neuroarthropathy in this high risk patient population have stimulated much surgical interest to create more stable osseous constructs when open reduction of an ankle fracture/dislocation is required. The utilization of multiple syndesmotic screws (pro-syndesmotic screws to further stabilize the ankle mortise has been reported by many foot and ankle surgeons. In addition, transarticular Steinmann pins have been described as an adjunct to traditional open reduction with internal fixation (ORIF of the ankle to better stabilize the talus, thus minimizing risk of further displacement, malunion, and Charcot neuroarthropathy. The authors present a unique technique of ORIF with pro-syndesmotic screws and the application of a multi-plane circular external fixator for management of a neglected diabetic ankle fracture that prevented further deformity while allowing a weight-bearing status. This technique may be utilized for the management of complex diabetic ankle fractures that are prone to future complications and possible limb loss.

  20. Energy policy and federalism

    Energy Technology Data Exchange (ETDEWEB)

    Thur, L.M. (ed.)

    1981-04-01

    Separate abstracts are prepared for six papers presented as the product of an international seminar on Energy Policy and Federalism in North America. Specially commissioned papers for the seminar are presented along with a summary of the discussions. The summary appears in English, French, and Spanish; the other papers are in English. (MCW)

  1. Agreement of 13 December 1991 between the Republic of Argentina, the Federative Republic of Brazil, the Brazilian-Argentine Agency for Accounting and Control of Nuclear Materials and the International Atomic Energy Agency for the Application of Safeguards

    International Nuclear Information System (INIS)

    1994-03-01

    The text of the Agreement (and the Protocol thereto) between the Republic of Argentina, the Federative Republic of Brazil, the Brazilian-Argentine Agency for Accounting and Control of Nuclear Materials and the International Atomic Energy Agency for the Application of Safeguards is reproduced in this document for the information of all Members. The Agreement was approved by the Agency's Board of Governors on 7 December 1991 and signed in Vienna on 13 December 1991

  2. Bone and Joint Problems Associated with Diabetes

    Science.gov (United States)

    ... bone metabolism (diabetic osteodystrophy): Time for recognition. Osteoporosis International. 2016;27:1931. Hull B, et al. Diabetes and bone. The American Journal of the Medical Sciences. 2016;351:356. What people with diabetes need ...

  3. Endotoxemia is associated with an increased risk of incident diabetes.

    Science.gov (United States)

    Pussinen, Pirkko J; Havulinna, Aki S; Lehto, Markku; Sundvall, Jouko; Salomaa, Veikko

    2011-02-01

    Diabetes is accompanied with a chronic low-grade inflammation, which may in part be mediated by endotoxins derived from Gram-negative bacteria. We investigated in a population-based cohort whether endotoxemia is associated with clinically incident diabetes. The serum endotoxin activity was measured by limulus assay from the FINRISK97 cohort comprising 7,169 subjects aged 25-74 years and followed up for 10 years. Both the subjects with prevalent diabetes (n = 537) and those with incident diabetes (n = 462) had higher endotoxin activity than the nondiabetic individuals (P endotoxemia with an increased risk of incident diabetes was independent of the metabolic syndrome as defined either by the National Cholesterol Educational Program-Adult Treatment Panel III or the International Diabetes Federation. Endotoxin activity was linearly related (P metabolic syndrome. Both prevalent and incident diabetes were associated with endotoxemia, which may link metabolic disorders to inflammation. The results suggest that microbes play a role in the pathogenesis of diabetes.

  4. Neonatal delivery weight and risk of future maternal diabetes.

    Science.gov (United States)

    Stuart, Andrea E; Amer-Wåhlin, Isis; Källen, Karin B M

    2018-01-01

    To investigate associations between neonatal delivery weight and future risk of maternal type 1 or type 2 diabetes. Data included in the Swedish Medical Birth Registry and Swedish National Diabetes Registry were merged to include all women born during 1930-1989; patients with pre-existing diabetes or gestational diabetes were excluded. Cox regression analyses were performed to identify associations between the neonatal delivery weight from the most recent pregnancy and later occurrence of diabetes. There were 1 873 440 patients included in the analyses. An increased risk of type 1 (hazard ratio 3.60, 95% confidence interval [CI] 3.23-4.01) or type 2 diabetes (hazard ratio 2.77, 95% CI 2.68-2.87) was observed among patients who had a large for gestational age neonate compared with patients who had neonates within one standard definition of the mean weight for gestational age; the odds of developing type 1 (odds ratio 10.27, 95% CI 7.37-14.31) or type 2 diabetes (odds ratio 8.50, 95% CI 6.01-12.02) within 1 year of delivery was also increased compared with patients who had a neonate within one standard deviation of the mean weight for gestational age. Delivering a large for gestational age neonate was a potent risk factor for the later development of maternal type 1 or type 2 diabetes. © 2017 International Federation of Gynecology and Obstetrics.

  5. An international survey on hypoglycemia among insulin-treated type I and type II diabetes patients: Turkey cohort of the non-interventional IO HAT study.

    Science.gov (United States)

    Emral, Rıfat; Tetiker, Tamer; Sahin, Ibrahim; Sari, Ramazan; Kaya, Ahmet; Yetkin, İlhan; Cil, Sefika Uslu; Tütüncü, Neslihan Başcıl

    2018-02-13

    Limited real-world data are currently available on hypoglycemia in diabetes patients. The International Operations Hypoglycemia Assessment Tool (IO HAT) study was designed to estimate hypoglycemia in insulin-treated type I (T1DM) and type II (T2DM) diabetes mellitus patients from 9 countries. The data from Turkey cohort are presented here. A non-interventional study to determine the hypoglycemia incidence, retrospectively and prospectively, in Turkish T1DM and T2DM patients using a 2-part self-assessment questionnaire. Overall, 2348 patients were enrolled in the Turkey cohort (T1DM = 306 patients, T2DM = 2042 patients). In T1DM patients, 96.8% patients reported hypoglycemic events (Incidence rate [IR]: 68.6 events per patient-year [ppy]), prospectively, while 74.0% patients reported hypoglycemic events (IR: 51.7 events ppy), retrospectively. In T2DM patients, 95.9% patients (IR: 28.3 events ppy) reported hypoglycemic events, prospectively, while 53.6% patients (IR: 23.0 events ppy) reported hypoglycemic events, retrospectively. Nearly all patients reported hypoglycemia during the prospective period. This is a first patient-reported dataset on hypoglycemia in Turkish, insulin-treated diabetes patients. A high incidence of patient-reported hypoglycemia confirms that hypoglycemia remains under-estimated. Hypoglycemia increased healthcare utilization impacting patients' quality of life. Hypoglycemia remains a common side effect with insulin-treatment and strategies to optimize therapy and reduce hypoglycemia occurrence in diabetes patients are required. Clinicaltrials.gov, NCT02306681 (Date of registration: 12 Nov 2014; retrospectively registered).

  6. Frequency of the metabolic syndrome in type 2 diabetic subjects attending the diabetes clinic of a tertiary care hospital.

    Science.gov (United States)

    Imam, Syed Khalid; Shahid, Syed Khurram; Hassan, Asim; Alvi, Zakir

    2007-05-01

    To determine the frequency of the metabolic syndrome in patients with type 2 diabetes mellitus wiho attended the diabetes clinic of Liaquat National Hospital, Karachi. A descriptive study was conducted at the diabetes clinic of Liaquat National Hospital from June 2004 to December 2004. We enrolled 233 subjects with type 2 diabetes mellitus. Frequency of metabolic syndrome was estimated according to the criteria proposed by National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATP III), with adoption of the Asian criteria for abdominal obesity and recently proposed International Diabetes Federation (IDF) diagnostic criteria for metabolic syndrome. There were 233 patients with type 2 diabetes mellitus in whom 49.8% were men and 50.2% were women. Mean age was 49.9 years. By applying NCEP-ATP III criteria, metabolic syndrome was found in 79.7% type 2 diabetics, (45.5% women and 34.3% men), by applying IDF criteria, metabolic syndrome was identified in 68.1% of type 2 diabetics (43.7% women and 24.4% men). In our study the frequency of the metabolic syndrome was found significantly high, especially in women and at a relatively young age of 49.9 years.

  7. The present state of the diabetic clinic in the first department of internal medicine of Niigata University Hospital

    Energy Technology Data Exchange (ETDEWEB)

    Nakagawa, Osamu; Oyama, Yasuro; Suzuki, Katsunori [Niigata Univ. (Japan). School of Medicine] [and others

    1998-10-01

    The treatment of diabetic complications in Niigata University were reported. Of all patients, 23.6% were treated by diabetic therapy alone, 37.8% were administered with SU drug and, in addition, about 50% were treated by a glucosidase inhibitor ({alpha}GI) or troglitazone. Insulin was used in 26.2% of the patients. Patients with NIDDM in whom the onset of simple retinopathy could be specified, were divided into 2 groups; Group S, with simple retinopathy without progression and Group P, with progression to preproliferative or proliferative retinopathy. Between the 2 groups, there were significant differences in the period of suffering from simple retinopathy, HbA1c and TC b. The association of the retinopathy with the short period would mean that HbA1c and TC were poorly controlled in these patients. In attention to silent myocardial ischemia and significance of cerebral blood flow scintigraphy, there was no significant difference regarding the presence or absence of angina pain or incidence of abnormal findings of scintigraphy or coronary angiography. It was difficult to predict the presence of silent myocardial ischemia from the presence or absence of diabetic neuropathy. Cerebral blood flow scintigraphy was performed in 37 diabetic patients, 25 patients were allocated to a group having uneven distribution of RI which never detected normally and an ununiform drop of peripheral blood flow (Micro group) and 12 cases without these findings to another group (Non-micro group). In the Micro group, HbA1c was significantly higher and the incidence of diabetic nephropathy was also higher. {alpha}GI was used to improve postprandial hyperglycemia in patients with NIDDM. It was more effective when being used concomitantly with a SU agent although the effect tended to decrease relatively in the cases of long term use. Improvement was observed in 90% of the patients which showed BMI of 24.2 or above. (K.H.)

  8. International

    International Nuclear Information System (INIS)

    Anon.

    1997-01-01

    This rubric reports on 10 short notes about international economical facts about nuclear power: Electricite de France (EdF) and its assistance and management contracts with Eastern Europe countries (Poland, Hungary, Bulgaria); Transnuclear Inc. company (a 100% Cogema daughter company) acquired the US Vectra Technologies company; the construction of the Khumo nuclear power plant in Northern Korea plays in favour of the reconciliation between Northern and Southern Korea; the delivery of two VVER 1000 Russian reactors to China; the enforcement of the cooperation agreement between Euratom and Argentina; Japan requested for the financing of a Russian fast breeder reactor; Russia has planned to sell a floating barge-type nuclear power plant to Indonesia; the control of the Swedish reactor vessels of Sydkraft AB company committed to Tractebel (Belgium); the renewal of the nuclear cooperation agreement between Swiss and USA; the call for bids from the Turkish TEAS electric power company for the building of the Akkuyu nuclear power plant answered by three candidates: Atomic Energy of Canada Limited (AECL), Westinghouse (US) and the French-German NPI company. (J.S.)

  9. CHART OF ACCOUNTS OF THE RUSSIAN FEDERATION SHOULD BE DETAILED WITH REFORMING OF AN ACCOUNTING REPORTING ON THE BASIS OF THE INTERNATIONAL FINANCIAL REPORTING STANDARDS (IFRS

    Directory of Open Access Journals (Sweden)

    Gegetsik A. Tovmasyan

    2013-01-01

    Full Text Available The article deals with the problem related to information base of accounting (financial reporting, which depends on conducting accounting and creation of detailed classification of chart of accounts of the Russian Federation. It is offered to change the structure of the balance sheet and the report on changes of the capital in the Russian Federation with introduction of “paid-in capital” indicator which not only unifies the reporting according to IFRS, but also will allow objectively estimating and predicting results and risks of both business activity and investment activity.

  10. Declared and real physical activity in patients with type 2 diabetes mellitus as assessed by the International Physical Activity Questionnaire and Caltrac accelerometer monitor: a potential tool for physical activity assessment in patients with type 2 diabetes mellitus.

    Science.gov (United States)

    Mynarski, W; Psurek, A; Borek, Z; Rozpara, M; Grabara, M; Strojek, K

    2012-10-01

    The aims of this study were to assess and compare declared and real volume of physical activity (PA), and to evaluate correlations of these measurements with glycemic control (HbA1c) and body mass index (BMI), in patients with type 2 diabetes mellitus (T2DM). A group of 31 (16 women and 15 men) type 2 diabetic patients treated with insulin monotherapy, from (mean age=54 ± 3.6 years, BMI=29.7 ± 4.8 kg/m(2), T2DM treatment=9 ± 8 years, HbA1c 7 ± 1%) and not professionally active (unemployed or retired) was recruited. An assessment of energy cost (EC) of their weekly PA using International Physical Activity Questionnaire (IPAQ), and an accelerometer assessment was performed. Total energy expenditure of the declared weekly PA, calculated from the IPAQ (DPA) was 2513 ± 1349 METmin/week, and 2428 ± 1348, for male and female participants, respectively (p > 0.05). EC of the real PA (RPA), registered with the accelerometer was 4552 ± 2028 kcal/week, and 4032 ± 2288 kcal/week, for males, and females, respectively. Patients who demonstrated a high DPA, based on their IPAQ score, showed a significantly higher RPA, as registered by the accelerometer (p < 0.05). HbA1c and BMI did not correlate with their PA measurements. Our findings indicate that the IPAQ may serve as a potential tool for physical activity assessment with no further requirement for more sophisticated methods. Our results suggest that habitual physical activity has no impact on glycemic control and BMI in type 2 diabetic patients. However, further studies on a larger population are needed to explore these issues. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  11. The Concordance and Heritability of Type 2 Diabetes in 34,166 Twin Pairs From International Twin Registers

    DEFF Research Database (Denmark)

    Willemsen, G.; Ward, K. J.; Bell, C. G.

    2015-01-01

    Twin pairs discordant for disease may help elucidate the epigenetic mechanisms and causal environmental factors in disease development and progression. To obtain the numbers of pairs, especially monozygotic (MZ) twin pairs, necessary for in-depth studies while also allowing for replication, twin...... studies worldwide need to pool their resources. The Discordant Twin (DISCOTWIN) consortium was established for this goal. Here, we describe the DISCOTWIN Consortium and present an analysis of type 2 diabetes (T2D) data in nearly 35,000 twin pairs. Seven twin cohorts from Europe (Denmark, Finland, Norway...... and medication use, fasting glucose and insulin measures, or medical records. The prevalence of T2D ranged from 2.6% to 12.3% across the cohorts depending on age, body mass index (BMI), and national diabetes prevalence. T2D discordance rate was lower for MZ (5.1%, range 2.9-11.2%) than for same-sex dizygotic (DZ...

  12. Insulin Initiation in Type 2 Diabetes – Why, When and How?

    Directory of Open Access Journals (Sweden)

    Popa Simona Georgiana

    2016-03-01

    Full Text Available Type 2 diabetes is a progressive disease and, despite recent progress in the treatment of diabetes, the glycemic control usually deteriorates gradually and insulin therapy is needed. When insulin therapy should be started and which are the appropriate insulin therapy strategies, still represent subjects of debates. Insulin represents a therapeutic option in type 2 diabetes due to the existence of early β-cell dysfunction and significant reduction of β-cell mass in natural history of type 2 diabetes. The current guidelines recommend insulin in double therapy in association with metformin or in combination with metformin and other noninsulin agent. Initiation of insulin therapy is recommended in patients with newly diagnosed type 2 diabetes and symptomatic and/or presenting important hyperglycemia or elevated HbA1c. Initiation of insulin therapy in type 2 diabetes should take into consideration the pathophysiology of type 2 diabetes, the effects and the potential risks of insulin therapy, the guidelines recommendations and the barriers to insulin use. Literatures of only English language were analyzed from NCBI database. Guidelines were accessed electronically from organisations, i.e. American Diabetes Associations, American Association of Clinical Endocrinologists and American College of Endocrinology, European Association for the Study of Diabetes, International Diabetes Federation.

  13. Women and Diabetes

    Medline Plus

    Full Text Available ... Safety Emergency Preparedness International Programs News & Events Training & Continuing Education Inspections & Compliance Federal, State & Local Officials Consumers Health ...

  14. Women and Diabetes

    Medline Plus

    Full Text Available ... Products Advisory Committees Regulatory Information Safety Emergency Preparedness International Programs News & Events Training & Continuing Education Inspections & Compliance Federal, State & Local Officials Consumers Health ...

  15. Energetic Materials - Technology, Manufacturing and Processing, 27th International Annual Conference of ICT June 25 - June 28, 1996 Karisruhe, Federal Republic of Germany

    National Research Council Canada - National Science Library

    1997-01-01

    .... The 27th International ICT Annual Conference centers at the discussion of the art in research and development of modern rocket propellants, explosives, gun propellants and pyrotechnics emphasizing...

  16. Creeping Federalization

    DEFF Research Database (Denmark)

    Sweeney, Richard J.

    2003-01-01

    that make taxharmonization difficult to impose. Other types of harmonization have a less clear-cut costbenefitanalysis. A federal commercial code that is uniform across member states reducestransaction and information costs, compared to leaving important code issues to memberstates; further, many states may...

  17. Preventing diabetic nephropathy

    DEFF Research Database (Denmark)

    Hansen, H P; Lund, S S; Rossing, P

    2001-01-01

    was to audit the effect of angiotensin converting enzyme (ACE) inhibition on the progression of microalbuminuria and development of diabetic nephropathy. We consecutively identified 227 type 1 diabetic patients with persistent microalbuminuria (urinary AER between 30 and 300mg/24h, ELISA). According...... to the level (> or = 100 or 6% or international guidelines, all patients at high-risk were....... Glycaemic control and blood pressure remained unchanged during the study. The implementation of modified international guidelines regarding the use of ACE inhibition in the treatment of microalbuminuric type 1 diabetic patients reduced progression to diabetic nephropathy comparable to what has previously...

  18. A new tool, a better tool? Prevalence and performance of the International Diabetes Federation and the National Cholesterol Education Program criteria for metabolic syndrome in different ethnic groups

    NARCIS (Netherlands)

    Bindraban, N. R.; van Valkengoed, I. G. M.; Mairuhu, G.; Koster, R. W.; Holleman, F.; Hoekstra, J. B. L.; Koopmans, R. P.; Stronks, K.

    2008-01-01

    We used a population based study in the Netherlands of 330 Hindustani Surinamese, 586 African Surinamese, and 486 ethnic Dutch (Dutch) to describe the prevalence of the metabolic syndrome (MS) and the association with differences in cardiovascular disease in and between ethnic groups. Fasting blood

  19. Bariatric surgery: an IDF statement for obese Type 2 diabetes

    Science.gov (United States)

    Dixon, J B; Zimmet, P; Alberti, K G; Rubino, F

    2011-01-01

    The International Diabetes Federation Taskforce on Epidemiology and Prevention of Diabetes convened a consensus working group of diabetologists, endocrinologists, surgeons and public health experts to review the appropriate role of surgery and other gastrointestinal interventions in the treatment and prevention of Type 2 diabetes. The specific goals were: to develop practical recommendations for clinicians on patient selection; to identify barriers to surgical access and suggest interventions for health policy changes that ensure equitable access to surgery when indicated; and to identify priorities for research. Bariatric surgery can significantly improve glycaemic control in severely obese patients with Type 2 diabetes. It is an effective, safe and cost-effective therapy for obese Type 2 diabetes. Surgery can be considered an appropriate treatment for people with Type 2 diabetes and obesity not achieving recommended treatment targets with medical therapies, especially in the presence of other major co-morbidities. The procedures must be performed within accepted guidelines and require appropriate multidisciplinary assessment for the procedure, comprehensive patient education and ongoing care, as well as safe and standardized surgical procedures. National guidelines for bariatric surgery need to be developed for people with Type 2 diabetes and a BMI of 35 kg/m2 or more. PMID:21480973

  20. Provisional Measures in the Case Concerning Application of the International Convention on the Elimination of All Forms of Racial Discrimination (Georgia v. Russian Federation

    Directory of Open Access Journals (Sweden)

    Tobias Thienel

    2009-02-01

    , to facilitate humanitarian assistance, and to generally refrain from any action which might prejudice the rights under adjudication in the case. The Order of the Court was made by a vote of eight to seven, and gave rise to a Joint Dissenting Opinion by seven judges. Those judges expressed not only their dissent from the making of the Order, but also their disagreement with the majority’s finding of even prima facie jurisdiction.[3]

    The case has already raised a few interesting issues relating to the Court’s jurisdiction to indicate provisional measures, and to the interpretation of CERD. These issues were all hotly contested not only between the parties, but also between the judges of the ICJ. This note will give a brief overview of the decision of the Court, and will comment on some outstanding features of the different opinions expressed.


    [1]        Application of the International Convention on the Elimination of All Forms of Racial Discrimination (Georgia v. Russian Federation, Order of 15 October 2008 (Georgia v. Russia, available at http://www.icj-cij.org/docket/files/140/14801.pdf (last visited 10

  1. Diabetes in the young - a global view and worldwide estimates of numbers of children with type 1 diabetes.

    Science.gov (United States)

    Patterson, Chris; Guariguata, Leonor; Dahlquist, Gisela; Soltész, Gyula; Ogle, Graham; Silink, Martin

    2014-02-01

    This paper describes the methodology, results and limitations of the 2013 International Diabetes Federation (IDF) Atlas (6th edition) estimates of the worldwide numbers of prevalent cases of type 1 diabetes in children (United Nations 2012 Revision population estimates for 2013 for each country to obtain estimates of the number of prevalent cases. Data availability was highest for the countries in Europe (76%) and lowest for the countries in sub-Saharan Africa (8%). The prevalence estimates indicate that there are almost 500,000 children aged under 15 years with type 1 diabetes worldwide, the largest numbers being in Europe (129,000) and North America (108,700). Countries with the highest estimated numbers of new cases annually were the United States (13,000), India (10,900) and Brazil (5000). Compared with the prevalence estimates made in previous editions of the IDF Diabetes Atlas, the numbers have increased in most of the IDF Regions, often reflecting the incidence rate increases that have been well-documented in many countries. Monogenic diabetes is increasingly being recognised among those with clinical features of type 1 or type 2 diabetes as genetic studies become available, but population-based data on incidence and prevalence show wide variation due to lack of standardisation in the studies. Similarly, studies on type 2 diabetes in childhood suggest increased incidence and prevalence in many countries, especially in Indigenous peoples and ethnic minorities, but detailed population-based studies remain limited. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  2. Fiscal Federalism

    DEFF Research Database (Denmark)

    Feng, Xingyuan; Ljungwall, Christer; Guo, Sujian

    2013-01-01

    China's central–local relations have been marked by perpetual changes amidst economic restructuring. Fiscal decentralization on the expenditure side has been paralleled by centralization on the revenue side, accompanied by political centralization. Hence, our understanding of China's fiscal...... relations is not without controversy. This paper aims to make a theoretical contribution to the ongoing debate on ‘fiscal federalism’ by addressing crucial questions regarding China's central–local fiscal relations: first, to what extent do Chinese central–local fiscal relations conform to fiscal federalism...... in the Western literature? Second, are there any problems with existing principles of fiscal federalism and, if so, how to refine them? Third, how are refined principles relevant to the Chinese case and what policies should the Chinese government pursue in the future? Based on an in-depth and critical review...

  3. Federal databases

    International Nuclear Information System (INIS)

    Welch, M.J.; Welles, B.W.

    1988-01-01

    Accident statistics on all modes of transportation are available as risk assessment analytical tools through several federal agencies. This paper reports on the examination of the accident databases by personal contact with the federal staff responsible for administration of the database programs. This activity, sponsored by the Department of Energy through Sandia National Laboratories, is an overview of the national accident data on highway, rail, air, and marine shipping. For each mode, the definition or reporting requirements of an accident are determined and the method of entering the accident data into the database is established. Availability of the database to others, ease of access, costs, and who to contact were prime questions to each of the database program managers. Additionally, how the agency uses the accident data was of major interest

  4. The International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes--chapter 1: Key ethical requirements and progress toward the definition of an international regulatory framework.

    Science.gov (United States)

    Cozzi, Emanuele; Tallacchini, Mariachiara; Flanagan, Enda B; Pierson, Richard N; Sykes, Megan; Vanderpool, Harold Y

    2009-01-01

    The outstanding results recently obtained in islet xenotransplantation suggest that porcine islet clinical trials may soon be scientifically appropriate. Before the initiation of such clinical studies, however, it is essential that a series of key ethical and regulatory conditions are satisfied. As far as ethics is concerned, the fundamental requirements have been previously reported in a position paper of the Ethics Committee of the International Xenotransplantation Association. These include aspects related to the selection of adequately informed, appropriate recipients; animal breeding and welfare; safety issues and the need for a favorable risk/benefit assessment based on strong efficacy data in relevant xenotransplantation studies in the primate. As most diabetic patients are not at risk of short-term mortality without islet transplantation, only a small subset of patients could currently be considered for any type of islet transplant. However, there are potential advantages to xenotransplantation that could result in a favorable benefit-over-harm determination for islet xenotransplantation in this subpopulation and ultimately in a broader population of diabetic patients. With regard to regulatory aspects, the key concepts underlying the development of the regulatory models in existence in the United States, Europe and New Zealand are discussed. Each of these models provides an example of a well-defined regulatory approach to ensure the initiation of well-regulated and ethically acceptable clinical islet xenotransplantation trials. At this stage, it becomes apparent that only a well-coordinated international effort such as that initiated by the World Health Organization, aimed at harmonizing xenotransplantation procedures according to the highest ethical and regulatory standards on a global scale, will enable the initiation of clinical xenotransplantation trials under the best auspices for its success and minimize any risk of failure.

  5. Aerial Photography and Imagery, Ortho-Corrected, This imagery was acquired through a Federal Grant with Pictometry International. The resolution is 6" in more densly populated areas and 1' in the other areas., Published in 2011, Not Applicable scale, Chippewa County Government.

    Data.gov (United States)

    NSGIC Local Govt | GIS Inventory — Aerial Photography and Imagery, Ortho-Corrected dataset current as of 2011. This imagery was acquired through a Federal Grant with Pictometry International. The...

  6. Effects on Engagement and Health Literacy Outcomes of Web-Based Materials Promoting Physical Activity in People With Diabetes: An International Randomized Trial.

    Science.gov (United States)

    Muller, Ingrid; Rowsell, Alison; Stuart, Beth; Hayter, Victoria; Little, Paul; Ganahl, Kristin; Müller, Gabriele; Doyle, Gerardine; Chang, Peter; Lyles, Courtney R; Nutbeam, Don; Yardley, Lucy

    2017-01-23

    Developing accessible Web-based materials to support diabetes self-management in people with lower levels of health literacy is a continuing challenge. The objective of this international study was to develop a Web-based intervention promoting physical activity among people with type 2 diabetes to determine whether audiovisual presentation and interactivity (quizzes, planners, tailoring) could help to overcome the digital divide by making digital interventions accessible and effective for people with all levels of health literacy. This study also aimed to determine whether these materials can improve health literacy outcomes for people with lower levels of health literacy and also be effective for people with higher levels of health literacy. To assess the impact of interactivity and audiovisual features on usage, engagement, and health literacy outcomes, we designed two versions of a Web-based intervention (one interactive and one plain-text version of the same content) to promote physical activity in people with type 2 diabetes. We randomly assigned participants from the United Kingdom, Austria, Germany, Ireland, and Taiwan to either an interactive or plain-text version of the intervention in English, German, or Mandarin. Intervention usage was objectively recorded by the intervention software. Self-report measures were taken at baseline and follow-up (immediately after participants viewed the intervention) and included measures of health literacy, engagement (website satisfaction and willingness to recommend the intervention to others), and health literacy outcomes (diabetes knowledge, enablement, attitude, perceived behavioral control, and intention to undertake physical activity). In total, 1041 people took part in this study. Of the 1005 who completed health literacy information, 268 (26.67%) had intermediate or low levels of health literacy. The interactive intervention overall did not produce better outcomes than did the plain-text version. Participants in

  7. Standards of specialized diabetes care. Edited by Dedov I.I., Shestakova M.V. (7th edition

    Directory of Open Access Journals (Sweden)

    Ivan Ivanovich Dedov

    2015-03-01

    Full Text Available We are glad to present the 7th Edition of Standards of Diabetes Care. These evidence-based guidelines were designed to standardize and facilitate diabetes care in all regions of the Russian Federation. The Standards are updated on the regular basis to incorporate new data and relevant recommendations from national and international clinical societies, including World Health Organization Guidelines (WHO, 2011, 2013, International Diabetes Federation (IDF, 2011, 2012, 2013, American Diabetes Association (ADA, 2012, 2015, American Association of Clinical Endocrinologists (AACE, 2013, International Society for Pediatric and Adolescent Diabetes (ISPAD, 2014 and Russian Association of Endocrinologists (RAE, 2011, 2012. Current edition of the “Standards” also integrates results of completed randomized clinical trials (ADVANCE, ACCORD, VADT, UKPDS, etc., as well as findings from the national studies of diabetes mellitus (DM, conducted in close partnership with a number of Russian hospitals.Latest data indicates that prevalence of DM increased during the last decade more than two-fold, reaching some 387 million patients by the end of 2014. According to the current estimation by the International Diabetes Federation, 592 million patients will be suffering from DM by 2035. These observations resulted in the UN Resolution 61/225 passed on 20.12.2006 that encouraged all Member States “to develop national policies for the prevention, treatment and care of diabetes”.Like many other countries, Russian Federation experiences a sharp rise in the prevalence of DM. According to Russian State Diabetes Register, there are at least 4.1 million patients with DM in this country. However, the epidemiological survey conducted by the Federal Endocrinology Research Centre during 2002-2010 suggests that actual prevalence is 3 to 4 times greater than the officially recognized and, by this estimate, amounts to 9-10 million persons, comprising 7% of the national

  8. Mortality trends from diabetes mellitus in the seven socioeconomic regions of Mexico, 2000-2007.

    Science.gov (United States)

    Sánchez-Barriga, Juan Jesús

    2010-11-01

    To determine trends in mortality from diabetes mellitus nationwide according to federative entity, socioeconomic region, and sex and to establish the association between education level, federation entity of residence, and socioeconomic region and mortality from diabetes in Mexico during the years 2000-2007. Records of mortality associated with diabetes for 2000-2007 were obtained from the National Information System of the Secretariat of Health. This information is generated by the National Institute of Statistics, Geography and Informatics through death certificates. Codes of International Classification of Diseases, 10th Revision, that correspond to the basic cause of death from diabetes mellitus were identified. Rates of mortality by federative entity and socioeconomic region were calculated, along with the strength of association (obtained by Poisson regression) between federative entity of residence, socioeconomic region, and education level and mortality from diabetes. The seven socioeconomic regions elaborated by the National Institute of Statistics, Geography and Informatics include the 32 federative entities according to indicators related to well-being such as education, occupation, health, housing, and employment. Individuals who did not complete elementary school had a higher risk of dying from diabetes (relative risk [RR] 2.104, 95% confidence interval [CI] 2.089-2.119). The federative entity and socioeconomic region with the strongest association with mortality from diabetes were Mexico City (RR 2.5, CI 2.33-2.68 for 2000; RR 2.06, CI 1.95-2.18 for 2007) and region 7 (RR 2.47, CI 2.36-2.57 for 2000; RR 2.05, CI 1.98-2.13 for 2007). Mortality rates increased from 77.9 to 89.2 per 100,000 inhabitants in the period 2000-2007. Women had higher mortality than men. Individuals who did not complete elementary school had a higher risk of dying from diabetes (RR 2.104, CI 2.089-2.119). Mexico City as federative entity and socioeconomic region 7 presented the

  9. 75 FR 44794 - Rendezvous International v.

    Science.gov (United States)

    2010-07-29

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Rendezvous International v. Chief Cargo Services, Inc., Kaiser Apparel, Inc., Edco Logistics, Inc., Oriental... complaint has been filed with the Federal Maritime Commission (``Commission'') by Rendezvous International...

  10. Seventh meeting of the International Working Group on Gas-Cooled Reactors, Beckum, Federal Republic of Germany, 29-30 October 1987

    International Nuclear Information System (INIS)

    1988-06-01

    The document contains a summary report on the seventh meeting of the International Working Group on Gas-Cooled Reactors and 8 reports describing the national GCR programmes of Austria, China, France, Japan, Switzerland, USSR, UK and Commission of European Communities. A separate abstract was prepared for each of these reports. Refs and tabs

  11. The parliamentary political agenda: a tool for policy analysis of diabetes priorities in Spain.

    Science.gov (United States)

    Agudelo-Suárez, Andrés A; Ruiz-Cantero, María Teresa; González-Zapata, Laura I; Restrepo-Medrano, Juan Carlos; Ortiz-Barreda, Gaby M

    2012-01-01

    To analyze the political agenda on diabetes in Spain under democracy by considering the frequency and content of initiatives in the Spanish parliament. A systematic search of parliamentary interventions (1979-2010) reported on the Spanish Congress of Deputies' web page was carried out using the key word "diabetes". A descriptive study of the frequency of interventions was performed, followed by a content analysis, according to the priorities of the World Health Organization (WHO), the International Diabetes Federation and the Spanish Diabetes Federation. Other study variables were the year of presentation, legislature, type of initiative and whether a political decision was taken (yes/no). There were 59 interventions: 22% were related to the first international initiatives and 44.1% took place in the last two legislatures in response to the WHO's program Diabetes Action Now. A total of 32.2% of the initiatives addressed educational and social programs, while 23.7% addressed access to resources and health services. Most initiatives (74.6%) consisted of parliamentary questions to the government, which only required a response. Of the 15 initiatives requiring a decision to be taken, only eight were approved. Spanish legislators aim to comply with international standards. Nevertheless, political decision-making has sometimes been slow. Importantly, most of the political responsibilities related to health have been transferred to the autonomous regions. The updated National Diabetes Strategy in Spain will need to strengthen public health policies according to established international priorities. Monitoring parliamentary interventions has proven to be a valid tool for evaluating patterns of political debate and decisions on diabetes. Copyright © 2011 SESPAS. Published by Elsevier Espana. All rights reserved.

  12. Women and Diabetes

    Medline Plus

    Full Text Available ... Women For Women Homepage FDA Diabetes Information for Patients Page Last Updated: 02/16/2018 Note: If ... FDA Archive Combination Products Advisory Committees Regulatory Information Safety Emergency Preparedness International Programs News & Events Training & Continuing ...

  13. Studies of international organizations in the Russian Federation. Interview with Doctor of political sciences, Professor, Director of the Center for International Institutions Research (CIIR of RANEPA M.V. Larionova

    Directory of Open Access Journals (Sweden)

    S A Bokeriya

    2017-12-01

    Full Text Available Marina V. Larionova is a leading Russian expert in studying international institutions. In 2007 she defended her doctoral thesis on the theme: “Creating a common educational space in conditions of the development of integration processes in the European Union” at the Peoples’ Friendship University of Russia. In the period from 2002 to 2009 Marina Vladimirovna held the position of Vice-Rector of the National Research University “Higher School of Economics”, and now she is currently a professor at the Department of World Economy of the Faculty of World Economy and World Politics at HSE. Also in 2005-2016 she headed the Institute of International Organizations and International Cooperation of this University. Since 2014 Marina Vladimirovna is the Managing Director and Vice President for International Cooperation of the Russian Union of Industrialists and Entrepreneurs. Since 2015 she also heads the Center for International Institutions Research (CIIR in RANEPA. M.V. Larionova has more than 70 scientific publications, is member of the Political Science Academy, University Association for Contemporary European Studies (UACES and the president of the Association of Experts in the field of international development assistance. Marina Vladimirovna is also the chief editor of the scientific journal the International Organisations Research Journal (IORJ, a member of the editorial board of the Vestnik RUDN. International relations and a member of the editorial board of Global Summitry Journal - GSJ. In the interview, M.V. Larionova speaks about studies of international institutions (organizations both in Russia and in the world, describes main schools and research methodology.

  14. Evaluation of the reliability and validity of the Medical Outcomes Study sleep scale in patients with painful diabetic peripheral neuropathy during an international clinical trial

    Directory of Open Access Journals (Sweden)

    Hays Ron D

    2008-12-01

    Full Text Available Abstract Background Sleep is an important element of functioning and well-being. The Medical Outcomes Study Sleep Scale (MOS-Sleep includes 12 items assessing sleep disturbance, sleep adequacy, somnolence, quantity of sleep, snoring, and awakening short of breath or with a headache. A sleep problems index, grouping items from each of the former domains, is also available. This study evaluates the psychometric properties of MOS-Sleep Scale in a painful diabetic peripheral neuropathic population based on a clinical trial conducted in six countries. Methods Clinical data and health-related quality of life data were collected at baseline and after 12 weeks of follow-up. Overall, 396 patients were included in the analysis. Psychometric properties of the MOS-Sleep were assessed in the overall population and per country when the sample size was sufficient. Internal consistency reliability was assessed by Cronbach's alpha; the structure of the instrument was assessed by verifying item convergent and discriminant criteria; construct validity was evaluated by examining the relationships between MOS-Sleep scores and sleep interference and pain scores, and SF-36 scores; effect-sizes were used to assess the MOS-Sleep responsiveness. The study was conducted in compliance with United States Food and Drug Administration regulations for informed consent and protection of patient rights. Results Cronbach's alpha ranged from 0.71 to 0.81 for the multi-item dimensions and the sleep problems index. Item convergent and discriminant criteria were satisfied with item-scale correlations for hypothesized dimensions higher than 0.40 and tending to exceed the correlations of items with other dimensions, respectively. Taken individually, German, Polish and English language versions had good internal consistency reliability and dimension structure. Construct validity was supported with lower sleep adequacy score and greater sleep problems index scores associated with

  15. Multimodal optical measurement for study of lower limb tissue viability in patients with diabetes mellitus

    Science.gov (United States)

    Dremin, Viktor V.; Zherebtsov, Evgeny A.; Sidorov, Victor V.; Krupatkin, Alexander I.; Makovik, Irina N.; Zherebtsova, Angelina I.; Zharkikh, Elena V.; Potapova, Elena V.; Dunaev, Andrey V.; Doronin, Alexander A.; Bykov, Alexander V.; Rafailov, Ilya E.; Litvinova, Karina S.; Sokolovski, Sergei G.; Rafailov, Edik U.

    2017-08-01

    According to the International Diabetes Federation, the challenge of early stage diagnosis and treatment effectiveness monitoring in diabetes is currently one of the highest priorities in modern healthcare. The potential of combined measurements of skin fluorescence and blood perfusion by the laser Doppler flowmetry method in diagnostics of low limb diabetes complications was evaluated. Using Monte Carlo probabilistic modeling, the diagnostic volume and depth of the diagnosis were evaluated. The experimental study involved 76 patients with type 2 diabetes mellitus. These patients were divided into two groups depending on the degree of complications. The control group consisted of 48 healthy volunteers. The local thermal stimulation was selected as a stimulus on the blood microcirculation system. The experimental studies have shown that diabetic patients have elevated values of normalized fluorescence amplitudes, as well as a lower perfusion response to local heating. In the group of people with diabetes with trophic ulcers, these parameters also significantly differ from the control and diabetes only groups. Thus, the intensity of skin fluorescence and level of tissue blood perfusion can act as markers for various degrees of complications from the beginning of diabetes to the formation of trophic ulcers.

  16. Is Type 1 Diabetes Mellitus More Prevalent Than Expected in Transgender Persons? A Local Observation.

    Science.gov (United States)

    Defreyne, Justine; De Bacquer, Dirk; Shadid, Samyah; Lapauw, Bruno; T'Sjoen, Guy

    2017-09-01

    The International Diabetes Federation estimates that approximately 0.4% of the Belgian population is diagnosed with type 1 diabetes mellitus, which is similar to other industrialized countries. The prevalence of transgenderism is estimated at 0.6% to 0.7% of all adults in Western populations. In this study, we evaluated whether there was an increased prevalence of type 1 diabetes mellitus in transgender people in the local cohort. Medical records of transgender patients were analyzed retrospectively. From January 1, 2007 until October 10, 2016, 1,081 transgender patients presented at a tertiary reference center to start hormonal treatment. Nine of these 1,081 patients were previously diagnosed with type 1 diabetes mellitus and 1 was diagnosed with latent autoimmune diabetes in adults. A 2.3-fold higher prevalence of type 1 diabetes mellitus was observed in transgender patients. We concluded that type 1 diabetes mellitus was more prevalent in transgender patients than one would expect from population prevalences. This could be a spurious result in a local cohort, because a causal relation seems unlikely, but our finding might encourage other centers to investigate this putative association. Defreyne J, De Bacquer D, Shadid S, et al. Is Type 1 Diabetes Mellitus More Prevalent Than Expected in Transgender Persons? A Local Observation. Sex Med 2017;5:e215-e218. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  17. The active role of leguminous plant components in type 2 diabetes.

    Science.gov (United States)

    Gętek, Monika; Czech, Natalia; Muc-Wierzgoń, Małgorzata; Grochowska-Niedworok, Elżbieta; Kokot, Teresa; Nowakowska-Zajdel, Ewa

    2014-01-01

    Diabetes appears to be one of the most frequent noncommunicable diseases in the world. A permanent growth in the incidence of diabetes can be observed and according to the International Diabetes Federation (IDF) the year 2030 will mark the increase in the number of diabetics to 439 mln worldwide. Type 2 diabetes accounts for about 90% of all diabetes incidence. Nutrition model modification not only features the basic element in type 2 diabetes treatment but also constitutes the fundamental factor influencing a morbidity rate decrease. Leguminous plants are a key factor in the diabetic diet; plants such as pulses or soybeans are nutritious products valued highly in nutrition. These legumes are high in the content of wholesome protein and contain large amounts of soluble alimentary fiber fractions, polyunsaturated fatty acids, vitamins and minerals, and bioactive substances with antioxidant, anti-inflammatory, and anticancer activity. They are distinguished by the high amount of bioactive compounds that may interfere with the metabolism of glucose. The most significant bioactive compounds displaying antidiabetic activity in leguminous plants are as follows: genistein and daidzein, alpha-amylase inhibitors, and alpha-glucosidase inhibitors. In vitro research using leguminous plant extracts has confirmed their antidiabetic properties. Leguminous plants should be employed in the promotion of healthy lifestyles in terms of functional food.

  18. The Active Role of Leguminous Plant Components in Type 2 Diabetes

    Directory of Open Access Journals (Sweden)

    Monika Gętek

    2014-01-01

    Full Text Available Diabetes appears to be one of the most frequent noncommunicable diseases in the world. A permanent growth in the incidence of diabetes can be observed and according to the International Diabetes Federation (IDF the year 2030 will mark the increase in the number of diabetics to 439 mln worldwide. Type 2 diabetes accounts for about 90% of all diabetes incidence. Nutrition model modification not only features the basic element in type 2 diabetes treatment but also constitutes the fundamental factor influencing a morbidity rate decrease. Leguminous plants are a key factor in the diabetic diet; plants such as pulses or soybeans are nutritious products valued highly in nutrition. These legumes are high in the content of wholesome protein and contain large amounts of soluble alimentary fiber fractions, polyunsaturated fatty acids, vitamins and minerals, and bioactive substances with antioxidant, anti-inflammatory, and anticancer activity. They are distinguished by the high amount of bioactive compounds that may interfere with the metabolism of glucose. The most significant bioactive compounds displaying antidiabetic activity in leguminous plants are as follows: genistein and daidzein, alpha-amylase inhibitors, and alpha-glucosidase inhibitors. In vitro research using leguminous plant extracts has confirmed their antidiabetic properties. Leguminous plants should be employed in the promotion of healthy lifestyles in terms of functional food.

  19. Controle Interno e as Fundações de apoio à pesquisa universitária: uma análise do funcionamento do Controle Interno nas Fundações da Universidade Federal de Santa Catarina no ano de 2010 = Internal Control and foundations to support university research: a review of the functioning of internal control in the foundations of the Federal University of Santa Catarina in 2010

    Directory of Open Access Journals (Sweden)

    Natalia Kirchner Azevedo

    2010-09-01

    Full Text Available O Controle Interno tem por finalidade planejar, organizar e supervisionar informações por meio de medidas que buscam proteger o patrimônio, incrementar a eficiência operacional e promover obediência às diretrizes administrativas. Por gerenciar recursos públicos, o Controle Interno torna-se um importante órgão que atua como supervisor dos procedimentos internos. Diante disso, este artigo tem como objetivo verificar a existência e a atuação do Controle Interno nas cinco Fundações de Amparo à Pesquisa da Universidade Federal de Santa Catarina. Trata-se de um estudo descritivo, com abordagem qualitativa dos dados e fontes de coleta dos dados primária. Conclui-se que, apesar da importância do Controle Interno, apenas três Fundações apresentam um órgão de controle; constatou-se também que alguns dos procedimentos que auxiliam o desenvolvimento harmônico e possibilitam maior eficiência nas operações não são praticados em várias das Fundações analisadas, procedimentos como: plano de carreira, relatórios de desempenho, manuais internos, rotação de funcionários e segregação de funções. Os Controles Internos analisados demonstram integralizar informações entre os setores contábil, administrativo, financeiro, de pessoal e a unidade de gerenciamento de projetos. Os gestores reconhecem a importância do Controle Interno para a Fundação e são unanimes em afirmar o interesse nisso para a promoção da eficiência operacional.Internal control is designed to plan, organize and supervise information through measures that seek to protect assets, increase operational efficiency and promote adherence to administrative policies. Manage public resources for internal control becomes an important organ of internal control that acts as a supervisor of internal procedures. Thus, this study aims to verify the existence and operation of internal control in five Foundations of the Federal University of Santa Catarina. This is a

  20. Secondary hyperparathyroidism prevalence and profile, between diabetic and non-diabetic patients with stage 3 to 4 chronic kidney disease attended in internal medicine wards. MiPTH study.

    Science.gov (United States)

    Arévalo-Lorido, José Carlos; Carretero-Gómez, Juana; García-Sánchez, Francisco; Maciá-Botejara, Enrique; Ramiro-Lozano, José Manuel; Masero-Carretero, Antonio; Robles, Nicolás Roberto; Bureo-Dacal, Juan Carlos

    2016-01-01

    Secondary hyperparathyroidism (SHPTH) is a leading cause of renal osteodystrophy, and an independent risk factor for all-cause and cardiovascular mortality. Our aim is to establish differences in prevalence and profile of SHPTH, regarding diabetics or non-diabetics with chronic kidney disease (CKD). Cross-sectional multicenter study which included patients with stages 3 to 4 CKD. SHPTH was considered when the intact PTH levels (iPTH) were equal or higher than 70pg/ml. We divided the sample into two groups (diabetics and non-diabetics). We used robust statistical methods. 409 patients (214 diabetics) were studied. HPTH was found in 60.4% of diabetics vs 65% of non-diabetics (P=0.42). Diabetics with HPTH were younger (79.5 vs 82.3 years-old, P=0.005), and had more hypertension (P=0.0014), dyslipidemia (P=0.0001) and comorbidities. In multivariate analysis, we found a significant relationship in case of diabetics, with age (OR: 1.04, 95%CI 1.005-1.09 P=0.02 ), and with statins treatment (OR 2.3, 95%CI 1.17-4.54, P=0.01). The prevalence of SHPTH between the groups was similar, however, diabetics had more presence of hypertension and dyslipidemia, and SHPTH in this case was also related with moderate microalbuminuria and lower levels of vitamin D. An association with statins was also found in this group. Copyright © 2016 Diabetes India. Published by Elsevier Ltd. All rights reserved.

  1. 76 FR 1495 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-01-10

    ...-2010-0355] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The... complying with the current regulation 49 CFR 391.41(b)(3). [[Page 1496

  2. Women and Diabetes -- Diabetes Medicines

    Science.gov (United States)

    ... Audience For Women Women's Health Topics Women and Diabetes - Diabetes Medicines Share Tweet Linkedin Pin it More sharing ... 1-800-332-1088 to request a form. Diabetes Medicines The different kinds of diabetes medicines are ...

  3. Fundamentals of quality assessment of molecular amplification methods in clinical diagnostics. International Federation of Clinical Chemistry Scientific Division Committee on Molecular Biology Techniques.

    Science.gov (United States)

    Neumaier, M; Braun, A; Wagener, C

    1998-01-01

    The increasing interest in molecular biology diagnostics is a result of the tremendous gain of scientific knowledge in genetics, made possible especially since the introduction of amplification techniques. High expectations have been placed on genetic testing, and the number of laboratories now using the relevant technology is rapidly increasing--resulting in an obvious need for standardization and definition of laboratory organization. This communication is an effort towards that end. We address aspects that should be considered when structuring a new molecular diagnostic laboratory, and we discuss individual preanalytical and analytical procedures, from sampling to evaluation of assay results. In addition, different means of controlling contamination are discussed. Because the methodology is in constant change, no general standards can be defined. Accordingly, this publication is intended to serve as a recommendation for good laboratory practice and internal quality control and as a guide to troubleshooting, primarily in amplification techniques.

  4. Dietary Patterns and Their Associations with the Diet Quality Index-International (DQI-I) in Korean Women with Gestational Diabetes Mellitus.

    Science.gov (United States)

    Shin, Moon-Kyung; Kim, Yoo-Sun; Kim, Jung-Hyun; Kim, Sung-Hoon; Kim, Yuri

    2015-10-01

    The aim of this study was to examine dietary pattern, nutritional intake, and diet quality of Korean pregnant women with gestational diabetes mellitus (GDM). Between October 2008 and May 2012, 166 pregnant women diagnosed with GDM completed a questionnaire and dietary intake was assessed using a 3-day food record. Blood pressure, fasting plasma glucose, and glycated hemoglobin (HbA1c) concentrations were measured and oral glucose tolerance test (OGTT) was performed. Two major dietary patterns ("carbohydrate and vegetable" and "western" patterns) were identified through factor analysis. Dietary pattern scores for each dietary pattern were categorized into tertiles. The dietary quality index-international (DQI-I) was used to measure overall diet quality. Subjects with higher carbohydrate and vegetable pattern scores reported less physical activity (p pattern scores were associated with higher sodium intakes (p = 0.02), but lower intakes of fat (p = 0.002) and other micronutrients. On the other hand, higher western pattern scores were associated with higher fat intake (p = 0.0001), but lower intakes of sodium (p = 0.01) and other micronutrients. Higher scores for both dietary patterns were associated with lower scores in the moderation category of the DQI-I (p dietary pattern.

  5. Lack of Adoption of a Mobile App to Support Patient Self-Management of Diabetes and Hypertension in a Federally Qualified Health Center: Interview Analysis of Staff and Patients in a Failed Randomized Trial.

    Science.gov (United States)

    Thies, Kathleen; Anderson, Daren; Cramer, Benjamin

    2017-10-03

    Thousands of mobile health (mHealth) apps have been developed to support patients' management of their health, but the effectiveness of many of the apps remains unclear. While mHealth apps appear to hold promise for improving the self-management of chronic conditions across populations, failure to balance the system demands of the app with the needs, interests, or resources of the end users can undermine consumers' adoption of these technologies. The original aim of this study was to evaluate the effectiveness of a commercial mHealth app in improving clinical outcomes for adult patients in a Federally Qualified Health Center (FQHC) with uncontrolled diabetes and/or hypertension. Patients entered clinical data into the app, which also supported messaging between patients and providers. After a 4-month period of vigorous recruitment, the trial was suspended due to low enrollment and inconsistent use of the app by enrolled patients. The project aim was changed to understanding why the trial was unsuccessful. We used the user-task-context (eUTC) usability framework to develop a set of interview questions for patients and staff who were involved in the trial. All interviews were done by phone and lasted 20 to 30 minutes. Interviews were not recorded. There was a poor fit between the app, end users, and recruitment and treatment approaches in our setting. Usability testing might have revealed this prior to launch but was not an option. There was not sufficient time during routine care for clinical staff to familiarize patients with the app or to check clinical data and messages, which are unreimbursed activities. Some patients did not use the app appropriately. The lack of integration with the electronic health record (EHR) was cited as a problem for both patients and staff who also said the app was just one more thing to attend to. This brief trial underscores the pitfalls in the utilization of mHealth apps. Effective use of mHealth tools requires a good fit between the

  6. More Accurate Definition of Clinical Target Volume Based on the Measurement of Microscopic Extensions of the Primary Tumor Toward the Uterus Body in International Federation of Gynecology and Obstetrics Ib-IIa Squamous Cell Carcinoma of the Cervix

    International Nuclear Information System (INIS)

    Xie, Wen-Jia; Wu, Xiao; Xue, Ren-Liang; Lin, Xiang-Ying; Kidd, Elizabeth A.; Yan, Shu-Mei; Zhang, Yao-Hong; Zhai, Tian-Tian; Lu, Jia-Yang; Wu, Li-Li; Zhang, Hao; Huang, Hai-Hua; Chen, Zhi-Jian; Li, De-Rui; Xie, Liang-Xi

    2015-01-01

    Purpose: To more accurately define clinical target volume for cervical cancer radiation treatment planning by evaluating tumor microscopic extension toward the uterus body (METU) in International Federation of Gynecology and Obstetrics stage Ib-IIa squamous cell carcinoma of the cervix (SCCC). Patients and Methods: In this multicenter study, surgical resection specimens from 318 cases of stage Ib-IIa SCCC that underwent radical hysterectomy were included. Patients who had undergone preoperative chemotherapy, radiation, or both were excluded from this study. Microscopic extension of primary tumor toward the uterus body was measured. The association between other pathologic factors and METU was analyzed. Results: Microscopic extension toward the uterus body was not common, with only 12.3% of patients (39 of 318) demonstrating METU. The mean (±SD) distance of METU was 0.32 ± 1.079 mm (range, 0-10 mm). Lymphovascular space invasion was associated with METU distance and occurrence rate. A margin of 5 mm added to gross tumor would adequately cover 99.4% and 99% of the METU in the whole group and in patients with lymphovascular space invasion, respectively. Conclusion: According to our analysis of 318 SCCC specimens for METU, using a 5-mm gross tumor volume to clinical target volume margin in the direction of the uterus should be adequate for International Federation of Gynecology and Obstetrics stage Ib-IIa SCCC. Considering the discrepancy between imaging and pathologic methods in determining gross tumor volume extent, we recommend a safer 10-mm margin in the uterine direction as the standard for clinical practice when using MRI for contouring tumor volume

  7. More accurate definition of clinical target volume based on the measurement of microscopic extensions of the primary tumor toward the uterus body in international federation of gynecology and obstetrics Ib-IIa squamous cell carcinoma of the cervix.

    Science.gov (United States)

    Xie, Wen-Jia; Wu, Xiao; Xue, Ren-Liang; Lin, Xiang-Ying; Kidd, Elizabeth A; Yan, Shu-Mei; Zhang, Yao-Hong; Zhai, Tian-Tian; Lu, Jia-Yang; Wu, Li-Li; Zhang, Hao; Huang, Hai-Hua; Chen, Zhi-Jian; Li, De-Rui; Xie, Liang-Xi

    2015-01-01

    To more accurately define clinical target volume for cervical cancer radiation treatment planning by evaluating tumor microscopic extension toward the uterus body (METU) in International Federation of Gynecology and Obstetrics stage Ib-IIa squamous cell carcinoma of the cervix (SCCC). In this multicenter study, surgical resection specimens from 318 cases of stage Ib-IIa SCCC that underwent radical hysterectomy were included. Patients who had undergone preoperative chemotherapy, radiation, or both were excluded from this study. Microscopic extension of primary tumor toward the uterus body was measured. The association between other pathologic factors and METU was analyzed. Microscopic extension toward the uterus body was not common, with only 12.3% of patients (39 of 318) demonstrating METU. The mean (±SD) distance of METU was 0.32 ± 1.079 mm (range, 0-10 mm). Lymphovascular space invasion was associated with METU distance and occurrence rate. A margin of 5 mm added to gross tumor would adequately cover 99.4% and 99% of the METU in the whole group and in patients with lymphovascular space invasion, respectively. According to our analysis of 318 SCCC specimens for METU, using a 5-mm gross tumor volume to clinical target volume margin in the direction of the uterus should be adequate for International Federation of Gynecology and Obstetrics stage Ib-IIa SCCC. Considering the discrepancy between imaging and pathologic methods in determining gross tumor volume extent, we recommend a safer 10-mm margin in the uterine direction as the standard for clinical practice when using MRI for contouring tumor volume. Copyright © 2015 Elsevier Inc. All rights reserved.

  8. More Accurate Definition of Clinical Target Volume Based on the Measurement of Microscopic Extensions of the Primary Tumor Toward the Uterus Body in International Federation of Gynecology and Obstetrics Ib-IIa Squamous Cell Carcinoma of the Cervix

    Energy Technology Data Exchange (ETDEWEB)

    Xie, Wen-Jia [Department of Radiation Oncology, Cancer Hospital of Shantou University Medical College, Shantou, Guangdong Province (China); Wu, Xiao [Department of Pathology, Cancer Hospital of Shantou University Medical College, Shantou, Guangdong Province (China); Xue, Ren-Liang; Lin, Xiang-Ying [Department of Radiation Oncology, Cancer Hospital of Shantou University Medical College, Shantou, Guangdong Province (China); Kidd, Elizabeth A. [Department of Radiation Oncology, Stanford University, Stanford, California (United States); Yan, Shu-Mei [Department of Pathology, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong Province (China); Zhang, Yao-Hong [Department of Radiation Oncology, Chaozhou Hospital of Chaozhou City, Guangdong Province (China); Zhai, Tian-Tian; Lu, Jia-Yang; Wu, Li-Li; Zhang, Hao [Department of Radiation Oncology, Cancer Hospital of Shantou University Medical College, Shantou, Guangdong Province (China); Huang, Hai-Hua [Department of Pathology, The Second Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong Province (China); Chen, Zhi-Jian; Li, De-Rui [Department of Radiation Oncology, Cancer Hospital of Shantou University Medical College, Shantou, Guangdong Province (China); Xie, Liang-Xi, E-mail: xieliangxi1@qq.com [Department of Radiation Oncology, Cancer Hospital of Shantou University Medical College, Shantou, Guangdong Province (China)

    2015-01-01

    Purpose: To more accurately define clinical target volume for cervical cancer radiation treatment planning by evaluating tumor microscopic extension toward the uterus body (METU) in International Federation of Gynecology and Obstetrics stage Ib-IIa squamous cell carcinoma of the cervix (SCCC). Patients and Methods: In this multicenter study, surgical resection specimens from 318 cases of stage Ib-IIa SCCC that underwent radical hysterectomy were included. Patients who had undergone preoperative chemotherapy, radiation, or both were excluded from this study. Microscopic extension of primary tumor toward the uterus body was measured. The association between other pathologic factors and METU was analyzed. Results: Microscopic extension toward the uterus body was not common, with only 12.3% of patients (39 of 318) demonstrating METU. The mean (±SD) distance of METU was 0.32 ± 1.079 mm (range, 0-10 mm). Lymphovascular space invasion was associated with METU distance and occurrence rate. A margin of 5 mm added to gross tumor would adequately cover 99.4% and 99% of the METU in the whole group and in patients with lymphovascular space invasion, respectively. Conclusion: According to our analysis of 318 SCCC specimens for METU, using a 5-mm gross tumor volume to clinical target volume margin in the direction of the uterus should be adequate for International Federation of Gynecology and Obstetrics stage Ib-IIa SCCC. Considering the discrepancy between imaging and pathologic methods in determining gross tumor volume extent, we recommend a safer 10-mm margin in the uterine direction as the standard for clinical practice when using MRI for contouring tumor volume.

  9. Depression, anxiety and self-care behaviours of young adults with Type 2 diabetes : Results from the International Diabetes Management and Impact for Long-term Empowerment and Success (MILES) Study

    NARCIS (Netherlands)

    Browne, J. L.; Nefs, G.; Pouwer, F.; Speight, J.

    2015-01-01

    Aim Young adults with Type 2 diabetes have higher physical morbidity and mortality than other diabetes sub-groups, but differences in psychosocial outcomes have not yet been investigated. We sought to compare depression and anxiety symptoms and self-care behaviours of young adults with Type 2

  10. Prevalence of Metabolic Syndrome and its influence on microvascular complications in the Indian population with Type 2 Diabetes Mellitus. Sankara Nethralaya Diabetic Retinopathy Epidemiology And Molecular Genetic Study (SN-DREAMS, report 14

    Directory of Open Access Journals (Sweden)

    Raman Rajiv

    2010-11-01

    Full Text Available Abstract Background The Metabolic syndrome (MS consists of central obesity, glucose intolerance, hyperinsulinemia, low high density lipoproteins, high triglycerides and hypertension. Different studies have observed that MS causes microvascular complications in patients with type 2 diabetes. The aim of the study was to find out the prevalence of MS in the Indian population with type 2 diabetes mellitus in relation to gender, duration of diabetes, and to evaluate the influence of MS and its individual components on microvascular complications such as diabetic retinopathy, diabetic nephropathy and diabetic neuropathy. Methods A population-based cross sectional survey was conducted with 1414 patients having type 2 diabetes mellitus. The International Diabetes Federation (IDF criteria were used to identify the metabolic syndrome. Diabetic retinopathy was graded using the stereoscopic digital fundus photography. Neuropathy was assessed by measuring the vibration perception threshold through a sensitometer. Nephropathy was diagnosed by the presence of microalbuminuria in the first morning urine sample. Results The age and gender adjusted prevalence of MS, using the IDF criteria, in the South Indian population was 73.3%. The prevalence was higher in women (83.3%, compared to men (65.3%. In subjects with diabetes mellitus, without and with MS, the prevalence of retinopathy was 21.3% and 16.9% (p = 0.057; prevalence of nephropathy was 20.5% and 18.0% (p = 0.296, and prevalence of neuropathy was17.2% and 19.4% (p = 0.353 respectively. Overall and in women, the clustering of MS components led to an increase in the prevalence of diabetic nephropathy. The prevalence of retinopathy and neuropathy in MS subjects, who had diabetes for Conclusions The association of MS with microangiopathies decreased with an increase in the duration of diabetes. MS behaved differently in men and women. It may need to be managed differently in the two groups.

  11. [Report of the World Federation of Neurosurgical Societies (WFNS) international course and Cameroon Neurosurgery Society Congress (CNS) Yaoundé (Cameroon), 1st--4th October 2007].

    Science.gov (United States)

    Eyenga, V C; Ndoumbe, A; Eloundou, N J

    2008-04-01

    Neurosurgery remains a very marginal activity in sub-Saharan Africa. In this part of the world which counts nearly 40 countries, some do not have a single neurosurgeon, some have one to five, the number of ten neurosurgeons per country remaining an exception! In its concern of popularizing and of developing neurosurgery worldwide, the WFNS organized an international course in Africa, October 2007 2nd-3rd in Yaoundé (Cameroon). The Cameroon Neurosurgery Society (CNS) took this opportunity to organize its very first congress in the presence of the WFNS delegation from October 1st to 4th, 2007. The joint meeting with the WFNS was baptized the "African Week of Neurosurgery". This special event was a first in sub-Saharan Africa. The delegation of the WFNS, led by Professor J. Brotchi (Belgium) President of the WFNS, was made up of Professors A. Sousa (Brazil), Mr. Choux (France), N. Tribolet (Swiss), M. Arraez (Spain), A. Bricolo (Italy), A. Kamlichi (Morocco), G. Dechambenoit (France), K. Kalangu (Zimbabwe). Twenty three neurosurgeons coming from nine African countries (Cameroon, Nigeria, Gabon, Congo, Niger, Burkina Faso, Ivory Coast, Senegal, and Guinea) took an active part in work. The scientific success of this event led to the creation of the "Association of Neurological Surgeons of Africa (ANSA)" which will be the WFNS-Africa interface in order to insure the development of neurosurgery in Africa.

  12. Diabetes mellitus: Exploring the challenges in the drug development process.

    Science.gov (United States)

    Vaz, Julius A; Patnaik, Ashis

    2012-07-01

    Diabetes mellitus has reached epidemic proportions and continues to be a major burden on society globally. The International Diabetes Federation (IDF) estimated the global burden of diabetes to be 366 million in 2011 and predicted that by 2030 this will have risen to 552 million. In spite of newer and effective treatment options, newer delivery and diagnostic devices, stricter glycaemic targets, better treatment guidelines and increased awareness of the disease, baseline glycosylated hemoglobin remains relatively high in subjects diagnosed and treated with type 2 diabetes. The search continues for an ideal anti diabetic drug that will not only normalize blood glucose but also provide beta cell rest and possibly restoration of beta cell function. The development of anti diabetic drugs is riddled with fundamental challenges. The concept of beta cell rest and restoration is yet to be completely understood and proven on a long term. The ideal therapeutic approach to treating type 2 diabetes is not yet determined. Our understanding of drug safety in early clinical development is primarily limited to "Type A" reactions. Until marketing authorization most drugs are approved based on the principle of confirming non-inferiority with an existing gold standard or determining superiority to a placebo. The need to obtain robust pharmaco-economic data prior to marketing authorization in order to determine appropriate pricing of a new drug remains a major challenge. The present review outlines some of the challenges in drug development of anti-diabetic drugs citing examples of pulmonary insulin, insulin analogues, thiazolidinediones and the GLP1 analogues.

  13. Diabetes mellitus: Exploring the challenges in the drug development process

    Directory of Open Access Journals (Sweden)

    Julius A Vaz

    2012-01-01

    Full Text Available Diabetes mellitus has reached epidemic proportions and continues to be a major burden on society globally. The International Diabetes Federation (IDF estimated the global burden of diabetes to be 366 million in 2011 and predicted that by 2030 this will have risen to 552 million. In spite of newer and effective treatment options, newer delivery and diagnostic devices, stricter glycaemic targets, better treatment guidelines and increased awareness of the disease, baseline glycosylated hemoglobin remains relatively high in subjects diagnosed and treated with type 2 diabetes. The search continues for an ideal anti diabetic drug that will not only normalize blood glucose but also provide beta cell rest and possibly restoration of beta cell function. The development of anti diabetic drugs is riddled with fundamental challenges. The concept of beta cell rest and restoration is yet to be completely understood and proven on a long term. The ideal therapeutic approach to treating type 2 diabetes is not yet determined. Our understanding of drug safety in early clinical development is primarily limited to "Type A" reactions. Until marketing authorization most drugs are approved based on the principle of confirming non-inferiority with an existing gold standard or determining superiority to a placebo. The need to obtain robust pharmaco-economic data prior to marketing authorization in order to determine appropriate pricing of a new drug remains a major challenge. The present review outlines some of the challenges in drug development of anti-diabetic drugs citing examples of pulmonary insulin, insulin analogues, thiazolidinediones and the GLP1 analogues.

  14. Is diabetes mellitus a heart disease equivalent in women? Results from an international study of postmenopausal women in the Raloxifene Use for the Heart (RUTH) Trial

    NARCIS (Netherlands)

    Daniels, L.B.; Grady, D.; Mosca, L.; Collins, P.; Mitlak, B.H.; Amewou-Atisso, M.G.; Wenger, N.K.; Barrett-Connor, E.; Suryapranata, H.; et al.,

    2013-01-01

    BACKGROUND: Several studies have concluded that diabetes mellitus and heart disease carry similar risk for future cardiovascular disease (CVD). Most of these studies were too small to quantify independent risks specific to women. The purpose of this study was to determine whether diabetes mellitus

  15. Sensory Neurons Derived from Diabetic Rats Have Diminished Internal Ca2+ Stores Linked to Impaired Re-uptake by the Endoplasmic Reticulum

    Directory of Open Access Journals (Sweden)

    Elena Zherebitskaya

    2011-12-01

    Full Text Available Distal symmetrical sensory neuropathy in diabetes involves the dying back of axons, and the pathology equates with axonal dystrophy generated under conditions of aberrant Ca2+ signalling. Previous work has described abnormalities in Ca2+ homoeostasis in sensory and dorsal horn neurons acutely isolated from diabetic rodents. We extended this work by testing the hypothesis that sensory neurons exposed to long-term Type 1 diabetes in vivo would exhibit abnormal axonal Ca2+ homoeostasis and focused on the role of SERCA (sarcoplasmic/endoplasmic reticulum Ca2+-ATPase. DRG (dorsal root ganglia sensory neurons from age-matched normal and 3–5-month-old STZ (streptozotocin-diabetic rats (an experimental model of Type 1 diabetes were cultured. At 1–2 days in vitro an array of parameters were measured to investigate Ca2+ homoeostasis including (i axonal levels of intracellular Ca2+, (ii Ca2+ uptake by the ER (endoplasmic reticulum, (iii assessment of Ca2+ signalling following a long-term thapsigargin-induced blockade of SERCA and (iv determination of expression of ER mass and stress markers using immunocytochemistry and Western blotting. KCl- and caffeine-induced Ca2+ transients in axons were 2-fold lower in cultures of diabetic neurons compared with normal neurons indicative of reduced ER calcium loading. The rate of uptake of Ca2+ into the ER was reduced by 2-fold (P<0.05 in diabetic neurons, while markers for ER mass and ER stress were unchanged. Abnormalities in Ca2+ homoeostasis in diabetic neurons could be mimicked via long-term inhibition of SERCA in normal neurons. In summary, axons of neurons from diabetic rats exhibited aberrant Ca2+ homoeostasis possibly triggered by suboptimal SERCA activity that could contribute to the distal axonopathy observed in diabetes.

  16. Diabetes mellitus

    OpenAIRE

    Nessim Dayan, Edgard; Fundación Valle de Lili

    1996-01-01

    ¿Qué es la diabetes?/¿Cuantos tipos o formas de diabetes existen?/¿Cuáles son los síntomas de la diabetes?/¿cuál es la causa de la diabetes?/¿Quién tiene mayor riesgo de desarrollar diabetes?/¿Cómo se diagnostica la diabetes?/¿Cuál es el tratamiento de la diabetes?/¿Cuándo y cómo se controlan los niveles de glicemia?/¿Cuáles son las complicaciones de la diabetes?/Recomendaciones actuales y futuro de la diabetes.

  17. Renal Biopsy in Type 2 Diabetic Patients.

    Science.gov (United States)

    Espinel, Eugenia; Agraz, Irene; Ibernon, Meritxell; Ramos, Natalia; Fort, Joan; Serón, Daniel

    2015-05-18

    The majority of diabetic patients with renal involvement are not biopsied. Studies evaluating histological findings in renal biopsies performed in diabetic patients have shown that approximately one third of the cases will show pure diabetic nephropathy, one third a non-diabetic condition and another third will show diabetic nephropathy with a superimposed disease. Early diagnosis of treatable non-diabetic diseases in diabetic patients is important to ameliorate renal prognosis. The publication of the International Consensus Document for the classification of type 1 and type 2 diabetes has provided common criteria for the classification of diabetic nephropathy and its utility to stratify risk for renal failure has already been demonstrated in different retrospective studies. The availability of new drugs with the potential to modify the natural history of diabetic nephropathy has raised the question whether renal biopsies may allow a better design of clinical trials aimed to delay the progression of chronic kidney disease in diabetic patients.

  18. Women and Diabetes

    Medline Plus

    Full Text Available ... Regulatory Information Safety Emergency Preparedness International Programs News & Events Training & Continuing Education Inspections & Compliance Federal, State & Local Officials Consumers Health Professionals Science & Research Industry Scroll back to top Popular Content Home Latest ...

  19. Women and Diabetes

    Medline Plus

    Full Text Available ... Emergency Preparedness International Programs News & Events Training & Continuing Education Inspections & Compliance Federal, State & Local Officials Consumers Health Professionals Science & Research Industry Scroll back to top Popular Content ...

  20. Women and Diabetes

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    Full Text Available ... Emergency Preparedness International Programs News & Events Training & Continuing Education Inspections & Compliance Federal, State & Local Officials Consumers Health Professionals Science & Research Industry Scroll back to top Popular ...

  1. Diabetes Care in India.

    Science.gov (United States)

    Joshi, Shashank R

    2015-01-01

    Diabetes has become a major health care problem in India with an estimated 66.8 million people suffering from the condition, representing the largest number of any country in the world. The rising burden of diabetes has greatly affected the health care sector and economy in India. The goal of health care experts in India is to transform India into a diabetes care capital in the world. An expert detailed review of the medical literature with an Asian Indian context was performed. Recent epidemiologic studies from India point to a great burden from diabetes. Diabetes control in India is far from ideal with a mean hemoglobin A1c of 9.0%-at least 2.0% higher than suggested by international bodies. Nearly half of people with diabetes remain undetected, accounting for complications at the time of diagnosis. Screening can differentiate an asymptomatic individual at high risk from one at low risk for diabetes. Despite the large number of people with diabetes in India, awareness is low and needs to be addressed. Other challenges include balancing the need for glycemic control with risk reduction due to overly tight control, especially in high-risk groups and taking into account health care professional expertise, attitudes, and perceptions. Pharmacologic care should be individualized with early consideration of combination therapy. Regular exercise, yoga, mindful eating, and stress management form a cornerstone in the management of diabetes. Considering the high cost incurred at various steps of screening, diagnosis, monitoring, and management, it is important to realize the cost-effective measures of diabetes care that are necessary to implement. Result-oriented organized programs involving patient education, as well as updating the medical fraternity on various developments in the management of diabetes, are required to combat the current diabetes epidemic in India. Copyright © 2015. Published by Elsevier Inc.

  2. Control to goal of cardiometabolic risk factors among Nigerians living with type 2 diabetes mellitus.

    Science.gov (United States)

    Okafor, C I; Ofoegbu, E N

    2012-01-01

    Cardiovascular risk factors contribute to morbidity and mortality among diabetic patients. National and international guidelines on management of diabetes therefore emphasize control to goals of blood glucose, blood pressure, dyslipidemia, and obesity so as to minimize the development of complications and enhance the patients' quality of life. To evaluate the status of control to goals of cardiometabolic risk factors among the diabetic patients attending the Diabetes clinic of University of Nigeria Teaching Hospital, Enugu. A survey of 233 type 2 diabetic patients recruited from the Diabetes clinic of our hospital was carried out. Standard procedures as described in the WHO STEP instrument were used to determine the waist circumference, weight, height, and systolic and diastolic blood pressure. Fasting blood glucose and lipid profiles were also assessed. Therapeutic goals used to define risk or poor control were values adopted by expert groups such as American diabetes association (ADA), National cholesterol education program (NCEP), American association of clinical endocrinologist (AACE) and International diabetes federation (IDF). There were 98 males and 135 females with mean (SD) duration of diabetes mellitus (DM) of 6.7 (6.3) years. Suboptimal glycemic, blood pressure control and dyslipidemia were observed in 65.7%, 51.9%, 97.1% of the subjects respectively while 60.1% of the subjects were found to be overweight/obese. Comparing the mean indices of risk factors with the recommended therapeutic goals, status of control was optimal for HDL-cholesterol, waist circumference and triglycerides. All the other risk factors were suboptimal. Control to goals of cardiovascular risk factors is poor among the patients. There is the need to identify and tackle the possible contributing factors so as to reduce the morbidity and mortality in these patients.

  3. ROLE OF YOGA ON CARDIC AUTONOMIC FUNCTION TESTS AND COGNITION IN TYPE 2 DIABETES.

    Science.gov (United States)

    Rajani, Santhakumari Nagothu; Indla, Yogananda Reddy; Archana, R; Rajesh, P

    2015-01-01

    According to International Diabetic Federation, type 2 diabetic population is on the rise globally and cognitive decline is one of the complications seen in type 2 diabetes. The present study is aimed at exploring the role of regular practice of yoga on cognition in type 2 diabetes and also to study the relation between the cognition and functional status of autonomic nervous system by considering the Cardiac Autonomic (CAN) function tests. Ten type 2 diabetic subjects of both the sex, aged between 35-55 years, who practiced yoga for a period of six months at Yogi Vemana Yoga Research Institute were recruited as test group. Age and sex matched ten type 2 diabetic subjects were recruited as control group; both the group subjects are on oral hypoglycemic agents. Glycosylated hemoglobin concentration was estimated with Bio-Rad instrument, cognition was assessed with Addenbrooke's Cognitive Examination Revised battery and Cardiac autonomic function tests were also conducted. Unpaired student t test was performed and pyoga in combination with oral hypoglycemic agents has a positive effect on cognition in type 2 diabetes.

  4. 77 FR 76414 - William D. Ford Federal Direct Loan Program

    Science.gov (United States)

    2012-12-28

    ... Federal Regulations is available via the Federal Digital System at: www.gpo.gov/fdsys . At this site you... exempt from taxation under section 501(a) of the Internal Revenue Code; and [[Page 76415

  5. Economic and social impact of diabetes mellitus in a low-income country: A case-control study in Sudan.

    Science.gov (United States)

    Elrayah-Eliadarous, Hind A; Östenson, Claes-Göran; Eltom, Mohamed; Johansson, Pia; Sparring, Vibeke; Wahlström, Rolf

    2017-12-01

    Diabetes mellitus accounts for 11% of total health expenditure worldwide, and most people with diabetes live in low- and middle-income countries. The present study examined the economic and social effects attributed to diabetes in Sudan by calculating out-of-pocket medical expenses and the health and social effects of the disease for people with diabetes (n = 375) and their families compared with a non-diabetic control group (n = 375), matched for age, sex, and residence area. Data were obtained in 2013 in four states within the Sudan, via structured interviews, using instruments from the International Diabetes Federation. Descriptive statistics were used to analyze differences between case and control participants. The median total annual medical expenditure was fourfold higher for people with than without diabetes (US$579 vs US$148, respectively). Annual mean expenditure was 85% higher for those with diabetes (US$1004 vs US$544). People with diabetes were also significantly more likely to suffer from serious comorbidities, such as cardiovascular disorders and foot ulcers, compared with control participants. Moreover, those with diabetes reported a higher proportion of personal adverse social effects, such as being prevented from doing paid work or participating in education, both for themselves and their families. The high economic burden and adverse social effects on people with diabetes and their families in Sudan call for the development of evidence-based policy and program strategies for the prevention and management of diabetes, with an emphasis on low-resource communities. © 2017 Ruijin Hospital, Shanghai Jiaotong University School of Medicine and John Wiley & Sons Australia, Ltd.

  6. Quality of life, anxiety and depression symptoms in early and late pregnancy in women with pregestational diabetes.

    Science.gov (United States)

    Do, Nicoline C; Secher, Anna L; Cramon, Per; Ringholm, Lene; Watt, Torquil; Damm, Peter; Mathiesen, Elisabeth R

    2017-02-01

    The aim of this study was to explore changes in health-related quality of life, anxiety and depression symptoms during pregnancy in women with pregestational diabetes. An observational cohort study including 137 pregnant women with pregestational diabetes (110 with type 1 and 27 with type 2). To evaluate changes from early to late pregnancy, the internationally validated questionnaires 36-Item Short-Form Health Survey (SF-36) and Hospital Anxiety and Depression Scale (HADS) were completed at 8 and 33 gestational weeks. From early to late pregnancy, the SF-36 scales Physical Function, Role Physical, Bodily Pain and Physical Component Summary worsened (p quality of life deteriorated whereas mental quality of life improved slightly during pregnancy in women with pregestational diabetes. A minor reduction in anxiety and stable depression symptoms was observed. The results on mental health are reassuring, considering the great demands that pregnancy places on women with pregestational diabetes. © 2016 Nordic Federation of Societies of Obstetrics and Gynecology.

  7. Effect of Blood Glucose Fluctuation on Some Trace Elements and Aldosterone Hormone among Type II Diabetic Patients with Metabolic Syndrome

    International Nuclear Information System (INIS)

    Ezz El-Arab, A.; El Fouly, A.H.; Mahmoud, H.H.

    2014-01-01

    There is accumulating evidence determine that the metabolism of some trace elements is altered in diabetes mellitus (DM) type II. The current study aimed to evaluate the effect of serum blood glucose fluctuation during (Random, Fasting and Postprandial 2 hours state) on some trace elements such as Cadmium (Cd), Chromium (Cr), Manganese (Mn), Magnesium (Mg), Zinc (Zn), Copper (Cu), Sodium (Na), Potassium (K), and Aldosterone hormone in type II Diabetic patients associated with metabolic syndrome in comparison with healthy volunteers. The International Diabetes Federation (IFD) consensus the diagnosis of metabolic syndrome according to central obesity, lipid profile, blood glucose level and blood pressure. A significant change was observed in trace elements level (Cd, Cr, Mg, Mn, Zn, Cu, Na, and K) and Aldosterone hormone as a result of glucose fluctuation among type II diabetic patients.

  8. Diabetes Medicines

    Science.gov (United States)

    Diabetes means your blood glucose, or blood sugar, levels are too high. If you can't control your diabetes with wise food choices and physical activity, you may need diabetes medicines. The kind of medicine you take depends ...

  9. Diabetic ketoacidosis

    Science.gov (United States)

    Diabetic ketoacidosis (DKA) is a life-threatening problem that affects people with diabetes . It occurs when the body ... pubmed/29222370 . Pasquel FJ, Umpierrez GE. Hyperglycemic crises: diabetic ketoacidosis and hyperglycemic hyperosmolar state. In: Jameson JL, De ...

  10. 78 FR 54680 - NASA Federal Advisory Committees

    Science.gov (United States)

    2013-09-05

    ... Committee Management Division, Office of International and Interagency Relations, NASA Headquarters... AGENCY: National Aeronautics and Space Administration. ACTION: Annual Invitation for Public Nominations... invitation for public nominations for service on NASA Federal advisory committees. U.S. citizens may nominate...

  11. Parallel Federal/State Antitrust Investigations

    OpenAIRE

    Stephen Houck

    2012-01-01

    Those matters in which both federal and state antitrust authorities do take an interest usually have significant impacts across state lines and even international borders. Stephen D. Houck (Menaker & Herrmann LLP)

  12. The Federal Forecasters Conference--1999. Papers and Proceedings (10th, Washington, DC, June 24, 1999) and Selected Papers from the International Symposium on Forecasting (19th, Washington, DC, June 27-30, 1999).

    Science.gov (United States)

    Gerald, Debra E., Ed.

    The 10th Federal Forecasters Conference provided a forum where 127 forecasters from different federal agencies and other organizations met to discuss various aspects of the conference's theme, "Forecasting in the New Millennium," that could be applied in the United States. A keynote address, "Procedures for Auditing Federal Forecasts" by J. Scott…

  13. Childhood obesity affects adult metabolic syndrome and diabetes.

    Science.gov (United States)

    Liang, Yajun; Hou, Dongqing; Zhao, Xiaoyuan; Wang, Liang; Hu, Yuehua; Liu, Junting; Cheng, Hong; Yang, Ping; Shan, Xinying; Yan, Yinkun; Cruickshank, J Kennedy; Mi, Jie

    2015-09-01

    We seek to observe the association between childhood obesity by different measures and adult obesity, metabolic syndrome (MetS), and diabetes. Thousand two hundred and nine subjects from "Beijing Blood Pressure Cohort Study" were followed 22.9 ± 0.5 years in average from childhood to adulthood. We defined childhood obesity using body mass index (BMI) or left subscapular skinfold (LSSF), and adult obesity as BMI ≥ 28 kg/m(2). MetS was defined according to the joint statement of International Diabetes Federation and American Heart Association with modified waist circumference (≥ 90/85 cm for men/women). Diabetes was defined as fasting plasma glucose ≥ 7.0 mmol/L or blood glucose 2 h after oral glucose tolerance test ≥ 11.1 mmol/L or currently using blood glucose-lowering agents. Multiple linear and logistic regression models were used to assess the association. The incidence of adult obesity was 13.4, 60.0, 48.3, and 65.1 % for children without obesity, having obesity by BMI only, by LSSF only, and by both, respectively. Compared to children without obesity, children obese by LSSF only or by both had higher risk of diabetes. After controlling for adult obesity, childhood obesity predicted independently long-term risks of diabetes (odds ratio 2.8, 95 % confidence interval 1.2-6.3) or abdominal obesity (2.7, 1.6-4.7) other than MetS as a whole (1.2, 0.6-2.4). Childhood obesity predicts long-term risk of adult diabetes, and the effect is independent of adult obesity. LSSF is better than BMI in predicting adult diabetes.

  14. Russian Federation Rising Power: Strengths and Weaknesses

    OpenAIRE

    KEITAN, Ahmed Yousif

    2017-01-01

    The ongoing developments in the Russian Federation since the beginning of the twenty-first century have been a dramatic turning point in its role at regional and international levels. A series of attempt to redraw the balances and become an international force that ultimately leads to its main goal of changing the balance of power in the system and building a new international order. The Russian diplomatic activity has evolved from competition, conflict, and cooperation with other internation...

  15. Diabetes MILES--The Netherlands

    DEFF Research Database (Denmark)

    Nefs, Giesje; Bot, Mariska; Browne, Jessica L

    2012-01-01

    BACKGROUND: As the number of people with diabetes is increasing rapidly worldwide, a more thorough understanding of the psychosocial aspects of living with this condition has become an important health care priority. While our knowledge has grown substantially over the past two decades with respect...... to the physical, emotional and social difficulties that people with diabetes may encounter, many important issues remain to be elucidated. Under the umbrella of the Diabetes MILES (Management and Impact for Long-term Empowerment and Success) Study International Collaborative, Diabetes MILES--The Netherlands aims...... to examine how Dutch adults with diabetes manage their condition and how it affects their lives. Topics of special interest in Diabetes MILES--The Netherlands include subtypes of depression, Type D personality, mindfulness, sleep and sexual functioning. METHODS/DESIGN: Diabetes MILES--The Netherlands...

  16. Standards of specialized diabetes care. Edited by Dedov II, Shestakova MV (6th edition

    Directory of Open Access Journals (Sweden)

    Ivan Ivanovich Dedov

    2013-06-01

    Full Text Available Dear Colleagues!We are glad to present the 6th Edition of Standards of Diabetes Care. These evidence-based guidelines were designed to standardize and facilitate diabetes care in all regions of the Russian Federation. The Standards are updated on the regular basis to incorporate new data and relevant recommendations from national and international clinical societies, including World Health Organization Guidelines (WHO, 2011, International Diabetes Federation (IDF, 2011, American Diabetes Association (ADA, 2013, American Association of Clinical Endocrinologists (AACE, 2009, International Society for Pediatric and Adolescent Diabetes (ISPAD, 2009 and Russian Association of Endocrinologists (RAE, 2011, 2012. Current edition of the “Standards” also integrates results of completed randomized clinical trials (ADVANCE, ACCORD, VADT, UKPDS, etc., as well as findings from the national studies of diabetes mellitus (DM, conducted in close partnership with a number of Russian hospitals.Latest data indicates that prevalence of DM increased during the last decade more than two-fold, reaching some 371 million patients by 2013. According to the current estimation by the International Diabetes Federation, every tenth inhabitant of the planet will be suffering from DM by 2030. These observations resulted in the UN Resolution 61/225 passed on 20.12.2006 that encouraged all Member States “to develop national policies for the prevention, treatment and care of diabetes”.Like many other countries, Russian Federation experiences a sharp rise in the prevalence of DM. According to Russian State Diabetes Register, there are at least 3.799 million patients with DM in this country. However, the epidemiological survey conducted by the Federal Endocrinology Research Centre during 2002-2010 suggests that actual prevalence is 3 to 4 times greater than the officially recognized and, by this estimate, amounts to 9-10 million persons, comprising 7% of the

  17. Design and Usability Evaluation of Social Mobile Diabetes Management System in the Gulf Region.

    Science.gov (United States)

    Alanzi, Turki; Istepanian, Robert; Philip, Nada

    2016-09-26

    The prevalence of diabetes in the Gulf States is one of the highest globally. It is estimated that 20% of the population in the region has been diagnosed with diabetes and according to the International Diabetes Federation (IDF), five of the IDF's "top 10" countries for diabetes prevalence in 2011 and projected for 2030 are in this region. In recent years, there have been an increasing number of clinical studies advocating the use of mobile phone technology for diabetes self-management with improved clinical outcomes. However, there are few studies to date addressing the application of mobile diabetes management in the Gulf region, particularly in the Kingdom of Saudi Arabia (KSA), where there is exponential increase in mobile phone usage and access to social networking. The objective of this paper is to present the design and development of a new mobile health system for social behavioral change and management tailored for Saudi patients with diabetes called Saudi Arabia Networking for Aiding Diabetes (SANAD). A usability study for the SANAD system is presented to validate the acceptability of using mobile technologies among patients with diabetes in the KSA and the Gulf region. The SANAD system was developed using mobile phone technology with diabetes management and social networking modules. For the usability study the Questionnaire for User Interaction Satisfaction was used to evaluate the usability aspect of the SANAD system. A total of 33 users with type 2 diabetes participated in the study. The key modules of the SANAD system consist of (1) a mobile diabetes management module; (2) a social networking module; and (3) a cognitive behavioral therapy module for behavioral change issues. The preliminary results of the usability study indicated general acceptance of the patients in using the system with higher usability rating in patients with type 2 diabetes. We found that the acceptability of the system was high among Saudi patients with diabetes, and ongoing

  18. 18 June 2012 - DST Global Founder Y. Milner signing the guest book with Head of International Relations F. Pauss; visiting the AD facility in building 193 with AEGIS Collaboration Spokesperson M. Doser and Adviser for the Russian Federation T. Kurtyka. Managing Director I. Osborne also present with Mrs J. Milner and DST Global A. Lebedkina.

    CERN Multimedia

    Maximilien Brice

    2012-01-01

    18 June 2012 - DST Global Founder Y. Milner signing the guest book with Head of International Relations F. Pauss; visiting the AD facility in building 193 with AEGIS Collaboration Spokesperson M. Doser and Adviser for the Russian Federation T. Kurtyka. Managing Director I. Osborne also present with Mrs J. Milner and DST Global A. Lebedkina.

  19. Tuesday 28 January 2014 - K. E. Huthmacher Ministerialdirektor Provision for the Future - Basic and Sustainability Research Federal Ministry of Education and Research (BMBF) visiting the stands with R. Heuer CERN Director-General on the occasion of the Inauguration of the Industrial Exhibition Germany@CERN and visiting the ATLAS Cavern with D. Charlton ATLAS Collaboration Spokesperson and R. Voss Head of International Relations.

    CERN Multimedia

    Pantelia, Anna

    2014-01-01

    Tuesday 28 January - K. E. Huthmacher Ministerialdirektor Provision for the Future - Basic and Sustainability Research Federal Ministry of Education and Research (BMBF) visiting the stands with R. Heuer CERN Director-General on the occasion of the Inauguration of the Industrial Exhibition Germany@CERN and visiting the ATLAS Cavern with D. Charlton ATLAS Collaboration Spokesperson and R. Voss Head of International Relations.

  20. 16 February 2012 - Permanent Representative of the Russian Federation to the United Nations Office and other international organisations at Geneva Ambassador A.Borodavkin signing the the guest book with CERN Director-General R. Heuer; visiting ATLAS underground experimental area with Collaboration Members O. Fedin, S. Malyukov and A. Romaniouk; throughout accompanied by Adviser T. Kurtyka.

    CERN Multimedia

    Maximilien Brice

    2012-01-01

    16 February 2012 - Permanent Representative of the Russian Federation to the United Nations Office and other international organisations at Geneva Ambassador A.Borodavkin signing the the guest book with CERN Director-General R. Heuer; visiting ATLAS underground experimental area with Collaboration Members O. Fedin, S. Malyukov and A. Romaniouk; throughout accompanied by Adviser T. Kurtyka.

  1. 75 FR 29744 - Federal Pell Grant, Federal Perkins Loan, Federal Work-Study, Federal Supplemental Educational...

    Science.gov (United States)

    2010-05-27

    ..., section 601 of the College Cost Reduction and Access Act of 2007 (CCRAA, Pub. L. 110-84) amended sections.... Education Savings and Asset Protection Allowance. This allowance protects a portion of net worth (assets... DEPARTMENT OF EDUCATION Federal Pell Grant, Federal Perkins Loan, Federal Work-Study, Federal...

  2. Federal Student Loan Programs

    Science.gov (United States)

    Federal Student Aid, US Department of Education, 2014

    2014-01-01

    For those needing a loan to attend college, think federal aid first. Federal student loans usually offer borrowers lower interest rates and have more flexible repayment terms and options than private student loans. This brief report answers the following questions about federal aid: (1) What is a federal student loan?; (2) What is a private…

  3. Diabetes - eye care

    Science.gov (United States)

    ... 26696680 . Read More Diabetes and eye disease High blood pressure Type 1 diabetes Type 2 diabetes Patient Instructions Diabetes and exercise Diabetes - keeping active Diabetes - low blood sugar - self-care Diabetes - preventing heart attack and ...

  4. diabetic patients

    Directory of Open Access Journals (Sweden)

    Mehraban Falahati

    2016-09-01

    candiduria and female gender, high FBS and urine glucose, uncontrolled diabetes (HbA1c ≥8, and acidic urine pH (P<0.05. Conclusion: Considering the high incidence rate of candiduria in diabetic patients, control of diabetes, predisposing factors, and causal relationships between diabetes and candiduria should be highlighted.

  5. An International, Multicenter, Observational Survey to Evaluate Diabetes Control in Subjects using Insulin for the Treatment of Type 1 and Type 2 Diabetes Mellitus in the Czech Republic and Slovak Republic: Study Protocol for a Cross-Sectional Survey

    Czech Academy of Sciences Publication Activity Database

    Brož, J.; Janíčková Žďárská, D.; Urbanová, J.; Brabec, Marek; Křivská, B.; Doničová, V.; Štěpánová, R.; Martinka, M.; Kvapil, M.

    2016-01-01

    Roč. 8, 9 June (2016), s. 13-20 ISSN 1179-1519 Institutional support: RVO:67985807 Keywords : insulin therapy * glycemic control * HbA1c * hypoglycemia * education * diabetes regimen adherence Subject RIV: FB - Endocrinology, Diabetology, Metabolism, Nutrition

  6. 78 FR 12821 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-02-25

    ...-2012-0350] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the... person has no established medical history or clinical diagnosis of diabetes mellitus currently requiring...

  7. 78 FR 12819 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-02-25

    ...-2012-0351] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... achieved by complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving... mellitus currently requiring insulin for control'' (49 CFR 391.41(b)(3)). FMCSA established its diabetes...

  8. 78 FR 65754 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-11-01

    ...-2013-0183] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor...-treated diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce...). Diabetes Mellitus and Driving Experience of the Applicants The Agency established the current requirement...

  9. 76 FR 71111 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-11-16

    ...-2011-0194] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The... be achieved by complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and...

  10. 77 FR 43417 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-07-24

    ...-2012-0109] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the Applicants The... person has no established medical history or clinical diagnosis of diabetes mellitus currently requiring...

  11. 76 FR 32015 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-06-02

    ...-2011-0080] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The... with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the...

  12. 77 FR 43901 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-07-26

    ...-2012-0108] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the Applicants The... person has no established medical history or clinical diagnosis of diabetes mellitus currently requiring...

  13. 77 FR 7232 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-02-10

    ...-2011-0327] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The... complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the...

  14. 76 FR 69795 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-11-09

    ...-2011-0193] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The... complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the...

  15. 76 FR 47288 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-08-04

    ...-2011-0125] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. [[Page... by complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving...

  16. 76 FR 47290 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-08-04

    ...-2011-0144] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The... the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the Applicants...

  17. 76 FR 26792 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-05-09

    ...-2011-0058] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The... current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the Applicants The...

  18. 76 FR 17475 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-03-29

    ...-0058] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM... must provide for individual assessment of drivers with diabetes mellitus, and be consistent with the...

  19. 76 FR 22940 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-04-25

    ...-2011-0025] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The... complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the...

  20. 76 FR 27376 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-05-11

    ...-2011-0040] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The... with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the...

  1. 77 FR 536 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-01-05

    ...-2011-0301] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The... complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the...

  2. 76 FR 22941 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-04-25

    ...-2011-0011] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The... be achieved by complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and...

  3. 78 FR 35088 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-06-11

    ...-2013-0015] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... would be achieved by complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and... of diabetes mellitus currently requiring insulin for control'' (49 CFR 391.41(b)(3)). FMCSA...

  4. 77 FR 65929 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-10-31

    ...-2012-0219] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the... person has no established medical history or clinical diagnosis of diabetes mellitus currently requiring...

  5. 78 FR 64267 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-10-28

    ...-0184] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... against persons with insulin- treated diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs... drivers with diabetes mellitus, and be consistent with the criteria described in section 4018 of the...

  6. 77 FR 17116 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-03-23

    ...-2011-0381] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The... the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the Applicants...

  7. 78 FR 76397 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-12-17

    ...-2013-0187] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... would be achieved by complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and... of diabetes mellitus currently requiring insulin for control'' (49 CFR 391.41(b)(3)). FMCSA...

  8. 77 FR 532 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-01-05

    ...-2011-0300] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The... included in this notice. Diabetes Mellitus and Driving Experience of the Applicants The Agency established...

  9. 78 FR 1926 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-01-09

    ...-2012-0347] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the Applicants... person has no established medical history or clinical diagnosis of diabetes mellitus currently requiring...

  10. 76 FR 61139 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-10-03

    ...-2011-0192] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The... complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the...

  11. 76 FR 79759 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-12-22

    ...-2011-0278] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The... complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the...

  12. 78 FR 5559 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-01-25

    ...-2012-0348] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the... person has no established medical history or clinical diagnosis of diabetes mellitus currently requiring...

  13. 78 FR 50482 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-08-19

    ...-0183] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM... revision must provide for individual assessment of drivers with diabetes mellitus, and be consistent with...

  14. 77 FR 33264 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-06-05

    ...-2012-0044] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the... person has no established medical history or clinical diagnosis of diabetes mellitus currently requiring...

  15. 76 FR 44650 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-07-26

    ...-2011-0143] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The... complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the...

  16. 78 FR 37272 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-06-20

    ...-2013-0017] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... achieved by complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving... mellitus currently requiring insulin for control'' (49 CFR 391.41(b)(3)). FMCSA established its diabetes...

  17. 77 FR 25227 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-04-27

    ...-2011-0383] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The... the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the Applicants...

  18. 76 FR 72031 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-11-21

    ...-0301] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM...).\\1\\ The revision must provide for individual assessment of drivers with diabetes mellitus, and be...

  19. 78 FR 37273 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-06-20

    ...-2013-0016] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... achieved by complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving... mellitus currently requiring insulin for control'' (49 CFR 391.41(b)(3)). FMCSA established its diabetes...

  20. 77 FR 75493 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-12-20

    ...-2012-0282] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the... person has no established medical history or clinical diagnosis of diabetes mellitus currently requiring...

  1. 77 FR 59447 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-09-27

    ...-0281] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM... drivers with diabetes mellitus, and be consistent with the criteria described in section 4018 of the...

  2. 77 FR 38383 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-06-27

    ...-2012-0107] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the Applicants The... person has no established medical history or clinical diagnosis of diabetes mellitus currently requiring...

  3. 78 FR 7855 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-02-04

    ...-2012-0349] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... achieved by complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving... mellitus currently requiring insulin for control'' (49 CFR 391.41(b)(3)). FMCSA established its diabetes...

  4. 77 FR 3549 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-01-24

    ...-0368] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM...\\ The revision must provide for individual assessment of drivers with diabetes mellitus, and be...

  5. 78 FR 60014 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-09-30

    ...-2013-0020] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... achieved by complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving... of diabetes mellitus currently requiring insulin for control'' (49 CFR 391.41(b)(3)). FMCSA...

  6. 78 FR 56988 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-09-16

    ...-0186] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... against persons with insulin-treated diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs... individuals listed in this notice have recently requested such an exemption from the diabetes prohibition in...

  7. 78 FR 26422 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-05-06

    ...-2013-0012] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... achieved by complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving... mellitus currently requiring insulin for control'' (49 CFR 391.41(b)(3)). FMCSA established its diabetes...

  8. 78 FR 65034 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-10-30

    ...-0190] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... against persons with insulin- treated diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs... drivers with diabetes mellitus, and be consistent with the criteria described in section 4018 of the...

  9. 77 FR 51845 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-08-27

    ...-2012-0163] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the Applicants The... person has no established medical history or clinical diagnosis of diabetes mellitus currently requiring...

  10. 77 FR 5873 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-02-06

    ...-2011-0326] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The... complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the...

  11. 76 FR 9867 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-02-22

    ...-2010-0427] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The... with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the...

  12. 77 FR 70529 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-11-26

    ...-2012-0281] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the... person has no established medical history or clinical diagnosis of diabetes mellitus currently requiring...

  13. 76 FR 79756 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-12-22

    ...-0326] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM...).\\1\\ The revision must provide for individual assessment of drivers with diabetes mellitus, and be...

  14. 77 FR 17111 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-03-23

    ...-0042] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM... revision must provide for individual assessment of drivers with diabetes mellitus, and be consistent with...

  15. 77 FR 75492 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-12-20

    ...-2012-0283] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the Applicants... person has no established medical history or clinical diagnosis of diabetes mellitus currently requiring...

  16. 77 FR 18302 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-03-27

    ...-0043] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM... for individual assessment of drivers with diabetes mellitus, and be consistent with the criteria...

  17. 76 FR 53707 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-08-29

    ...-2011-0145] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The... complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the...

  18. 77 FR 64585 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-10-22

    ...-2012-0218] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the Applicants The... person has no established medical history or clinical diagnosis of diabetes mellitus currently requiring...

  19. 78 FR 50486 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-08-19

    ...-0182] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM... revision must provide for individual assessment of drivers with diabetes mellitus, and be consistent with...

  20. 78 FR 16758 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-03-18

    ...-0012] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM... individual assessment of drivers with diabetes mellitus, and be consistent with the criteria described in...

  1. 77 FR 29446 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-05-17

    ...-2012-0043] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the Applicants The... vehicle if that person has no established medical history or clinical diagnosis of diabetes mellitus...

  2. 78 FR 39825 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-07-02

    ...-2013-0018] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diagnosis of diabetes mellitus currently requiring insulin for control'' [49 CFR 391.41(b)(3)]. FMCSA... Congress on the Feasibility of a Program to Qualify Individuals with Insulin-Treated Diabetes Mellitus to...

  3. 77 FR 48587 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-08-14

    ...-0217] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM... drivers with diabetes mellitus, and be consistent with the criteria described in section 4018 of the...

  4. 77 FR 59450 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-09-27

    ...-2012-0164] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the Applicants The... person has no established medical history or clinical diagnosis of diabetes mellitus currently requiring...

  5. 78 FR 50140 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-08-16

    ...-2013-0019] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... achieved by complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving... mellitus currently requiring insulin for control'' (49 CFR 391.41(b)(3)). FMCSA established its diabetes...

  6. 78 FR 76400 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-12-17

    ...-2013-0189] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor...-treated diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce...). Diabetes Mellitus and Driving Experience of the Applicants The Agency established the current requirement...

  7. 78 FR 76398 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-12-17

    ...-2013-0188] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... would be achieved by complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and... of diabetes mellitus currently requiring insulin for control'' (49 CFR 391.41(b)(3)). FMCSA...

  8. 78 FR 65031 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-10-30

    ...-2013-0182] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... would be achieved by complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and... of diabetes mellitus currently requiring insulin for control'' (49 CFR 391.41(b)(3)). FMCSA...

  9. 77 FR 46791 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-08-06

    ...-2012-0162] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the... person has no established medical history or clinical diagnosis of diabetes mellitus currently requiring...

  10. Cardiovascular diseases and diabetes as economic and developmental challenges in Africa.

    Science.gov (United States)

    Kengne, Andre Pascal; June-Rose McHiza, Zandile; Amoah, Albert George Baidoe; Mbanya, Jean-Claude

    2013-01-01

    Current estimates and projections suggest that the burden of cardiovascular diseases (CVDs), diabetes and related risk factors in African countries is important, somewhat unique and rapidly growing. Various segments of the population are affected; however, the group mostly affected is young adults residing in urban areas, and increasingly those in the low socioeconomic strata. The African milieu/environment is compounded by weak health systems, which are unable to cope with the looming double burden of communicable and chronic non-communicable diseases. This review discusses the economic and developmental challenges posed by CVDs and diabetes in countries in Africa. Using several lines of evidence, we demonstrate that the cost of care for major CVDs and diabetes is beyond the coping capacities of individuals, households, families and governments in most African countries. We have reviewed modeling studies by the International Diabetes Federation (IDF) and other major international agencies on the current and projected impact that CVDs and diabetes have on the economy and development of countries in the region. Locally, appropriate strategies to limit the impact of the conditions on the economies and development of countries in Africa are suggested and discussed. These include monitoring diseases and risk factors, and primordial, primary and secondary preventions implemented following a life-course perspective. Structural, logistic, human capacity and organizational challenges to be surmounted during the implementations of these strategies will be reviewed. © 2013.

  11. Stromal cells from the adipose tissue-derived stromal vascular fraction and culture expanded adipose tissue-derived stromal/stem cells: a joint statement of the International Federation for Adipose Therapeutics and Science (IFATS) and the International Society for Cellular Therapy (ISCT).

    Science.gov (United States)

    Bourin, Philippe; Bunnell, Bruce A; Casteilla, Louis; Dominici, Massimo; Katz, Adam J; March, Keith L; Redl, Heinz; Rubin, J Peter; Yoshimura, Kotaro; Gimble, Jeffrey M

    2013-06-01

    Adipose tissue is a rich and very convenient source of cells for regenerative medicine therapeutic approaches. However, a characterization of the population of adipose-derived stromal and stem cells (ASCs) with the greatest therapeutic potential remains unclear. Under the authority of International Federation of Adipose Therapeutics and International Society for Cellular Therapy, this paper sets out to establish minimal definitions of stromal cells both as uncultured stromal vascular fraction (SVF) and as an adherent stromal/stem cells population. Phenotypic and functional criteria for the identification of adipose-derived cells were drawn from the literature. In the SVF, cells are identified phenotypically by the following markers: CD45-CD235a-CD31-CD34+. Added value may be provided by both a viability marker and the following surface antigens: CD13, CD73, CD90 and CD105. The fibroblastoid colony-forming unit assay permits the evaluation of progenitor frequency in the SVF population. In culture, ASCs retain markers in common with other mesenchymal stromal/stem cells (MSCs), including CD90, CD73, CD105, and CD44 and remain negative for CD45 and CD31. They can be distinguished from bone-marrow-derived MSCs by their positivity for CD36 and negativity for CD106. The CFU-F assay is recommended to calculate population doublings capacity of ASCs. The adipocytic, chondroblastic and osteoblastic differentiation assays serve to complete the cell identification and potency assessment in conjunction with a quantitative evaluation of the differentiation either biochemically or by reverse transcription polymerase chain reaction. The goal of this paper is to provide initial guidance for the scientific community working with adipose-derived cells and to facilitate development of international standards based on reproducible parameters. Copyright © 2013 International Society for Cellular Therapy. All rights reserved.

  12. New Therapeutic Approaches to Prevent or Delay Beta-Cell Failure in Diabetes

    Directory of Open Access Journals (Sweden)

    Ionica Floriana Elvira

    2015-09-01

    Full Text Available Background and aims: The most recent estimates of International Diabetes Federation indicate that 382 million people have diabetes, and the incidence of this disease is increasing. While in type 1 diabetes mellitus (T1DM beta-cell death is autoimmunemediated, type 2 diabetes mellitus (T2DM results from an interaction between genetic and environmental factors that impair beta-cell function and insulin action. Many people with T2DM remain unaware of their illness for a long time because symptoms may take years to appear or be recognized, while the body is affected by excess blood glucose. These patients are often diagnosed only when diabetes complications have already developed. The aim of this article was to perform a review based on literature data on therapeutic modalities to prevent/delay beta cell function decline. Material and Methods: We searched MEDLINE from 2000 to the present to identify the therapeutic approaches to prevent or delay beta-cell failure in patients with T2DM. Results and conclusions: Several common polymorphisms in genes linked to monogenic forms of diabetes appear to influence the response to T2DM pharmacotherapy. Recent studies report the role of the G protein coupled receptor 40 (GPR40, also known as Free Fatty Acids Receptor 1 (FFAR1 in the regulation of beta-cell function- CNX-011-67 (a GPR40 agonist has the potential to provide good and durable glycemic control in T2DM patients.

  13. An Early Detection Method of Type-2 Diabetes Mellitus in Public Hospital

    Directory of Open Access Journals (Sweden)

    Hermansyah Hermansyah

    2011-08-01

    Full Text Available Diabetes is a chronic disease and major problem of morbidity and mortality in developing countries. The International Diabetes Federation estimates that 285 million people around the world have diabetes. This total is expected to rise to 438 million within 20 years. Type-2 diabetes mellitus (T2DM is the most common type of diabetes and accounts for 90-95% of all diabetes. Detection of T2DM from various factors or symptoms became an issue which was not free from false presumptions accompanied by unpredictable effects. According to this context, data mining and machine learning could be used as an alternative way help us in knowledge discovery from data. We applied several learning methods, such as instance based learners, naive bayes, decision tree, support vector machines, and boosted algorithm acquire information from historical data of patients medical records of Mohammad Hoesin public hospital in Southern Sumatera. Rules are extracted from Decision tree to offer decision-making support through early detection of T2DM for clinicians.

  14. The inverse relation of CA-125 to diabetes, metabolic syndrome, and associated clinical variables.

    Science.gov (United States)

    Esteghamati, Alireza; Seyedahmadinejad, Seyedomid; Zandieh, Ali; Esteghamati, Abdoulreza; Gharedaghi, Mohammad Hadi; Sadaghiani, Mohammad Salehi; Saadipoor, Afshin; Nakhjavani, Manouchehr

    2013-08-01

    We aimed to evaluate the association of carbohydrate antigen 125 (CA-125; also known as cancer antigen 125) with various anthropometric and metabolic measures and also with diabetes and metabolic syndrome. A total of 357 diabetic and nondiabetic subjects were enrolled. CA-125, anthropometric parameters, lipids, blood pressure, as well as glycemic and insulin resistance measures were assessed. Metabolic syndrome was defined according to the International Diabetes Federation (IDF) criteria. CA-125 was lower in subjects with diabetes and/or metabolic syndrome [median (interquartile range) of 8.20 (5.70-11.57) and 9.55 (6.50-16.25) U/mL for diabetic and nondiabetic subjects, respectively, PCA-125 (PCA-125 (PCA-125. However, none of insulin resistance measures remained in the model after adjusting for other clinical variables. CA-125 is inversely correlated with diabetes status, metabolic syndrome, and their associated anthropometric and metabolic measures. Furthermore, CA-125 is independently associated with waist circumference, apolipoprotein B, and systolic blood pressure, but not with any insulin resistance measures.

  15. Diabetes and Wound Angiogenesis

    Science.gov (United States)

    Okonkwo, Uzoagu A.; DiPietro, Luisa A.

    2017-01-01

    Diabetes Mellitus Type II (DM2) is a growing international health concern with no end in sight. Complications of DM2 involve a myriad of comorbidities including the serious complications of poor wound healing, chronic ulceration, and resultant limb amputation. In skin wound healing, which has definite, orderly phases, diabetes leads to improper function at all stages. While the etiology of chronic, non-healing diabetic wounds is multi-faceted, the progression to a non-healing phenotype is closely linked to poor vascular networks. This review focuses on diabetic wound healing, paying special attention to the aberrations that have been described in the proliferative, remodeling, and maturation phases of wound angiogenesis. Additionally, this review considers therapeutics that may offer promise to better wound healing outcomes. PMID:28671607

  16. The Charcot Foot in Diabetes

    Science.gov (United States)

    Frykberg, Robert G.; Armstrong, David G.; Boulton, Andrew J.M.; Edmonds, Michael; Van, Georges Ha; Hartemann, Agnes; Game, Frances; Jeffcoate, William; Jirkovska, Alexandra; Jude, Edward; Morbach, Stephan; Morrison, William B.; Pinzur, Michael; Pitocco, Dario; Sanders, Lee; Wukich, Dane K.; Uccioli, Luigi

    2011-01-01

    The diabetic Charcot foot syndrome is a serious and potentially limb-threatening lower-extremity complication of diabetes. First described in 1883, this enigmatic condition continues to challenge even the most experienced practitioners. Now considered an inflammatory syndrome, the diabetic Charcot foot is characterized by varying degrees of bone and joint disorganization secondary to underlying neuropathy, trauma, and perturbations of bone metabolism. An international task force of experts was convened by the American Diabetes Association and the American Podiatric Medical Association in January 2011 to summarize available evidence on the pathophysiology, natural history, presentations, and treatment recommendations for this entity. PMID:21868781

  17. A cross-sectional international survey of continuous subcutaneous insulin infusion in 377 children and adolescents with type 1 diabetes mellitus from 10 countries

    NARCIS (Netherlands)

    Danne, T; Battelino, T; Kordonouri, O; Hanas, R; Klinkert, C; Ludvigsson, J; Barrio, R; Aebi, C; Gschwend, S; Mullis, PE; Schumacher, U; Zumsteg, U; Morandi, A; Rabbone, [No Value; Cherubini, [No Value; Toni, S; de Beaufort, C; Hindmarsh, P; Sumner, A; van Waarde, WM; van den Berg, N; Phillip, M

    2005-01-01

    Objective: To document current practices using continuous subcutaneous insulin infusion (CSII) by downloading electronically the 90-d pump data held within the pump memory and relating that to clinical data from children and adolescents in different pediatric diabetes centers from Europe and Israel.

  18. Persistent lipid abnormalities in statin-treated patients with diabetes mellitus in Europe and Canada: results of the Dyslipidaemia International Study

    NARCIS (Netherlands)

    Leiter, L. A.; Lundman, P.; da Silva, P. M.; Drexel, H.; Jünger, C.; Gitt, A. K.; Absenger, Guun; Albrich, Ernst; Allinger, Berndt; Allinger, Stephan; Anacher, Gerald; Angermayr, Gertraud; Angermeier, Hermann; Anzengruber, Aneas; Archimanitis, Gabriele; Arnsteiner, Patricia; Auberger, Wolfgang; Azhary, Mawaheb; Barfuss, Michael; Bauer, Christian; Bauer, Birgit Elisabeth; Beclin, Thomas; Binder, Thomas; Binder, Gabriele; Böhler, Dietmar; Brändle, Johann; Breslmair, Jörg; Brettlecker, Marlis; Bürger, Michael; Calvi, Inge; Dorfinger, Werner; Doringer-Schnepf, Elisabeth; Eer, Anton; Eckmayr, Christine; Eder, Franz; Egermann, Margit; Erath, Michael; Etzinger, Michael; Etzinger, Claudia; Fiedler, Lothar; Filip, Wolfgang; Filip, Michaela; Föchterle, Johann; Fodor, Anita; Frieden, Thomas; Gareiss, Mertens; Gföllner, Peter; Ghamarian, Thomas; Goritschan, Michael; Haar, Klaus; Habeler, Gerhard; Hadjiivanov, Valery; Haiböck, Christian; Hammer, Regina; Hartmann, Siegfried; Haschkovitz, Herbert; Hauer, Walter; Hauer, Josef; Haunschmidt, Christian; Heimayr, Christine; Hengl, Wolfgang; Hengl, Gunter; Hermann, Rudolf; Herrmann, Rainer; Hillebrand, Roswitha; Hintersteininger, Otto; Hirsch, Michael; Hitzinger, Martin; Hochegger, Tanja; Hockl, Wolfgang; Hoi, Michael; Hörmann, Jan; Hudler, Brigitte; Imb, Gerhard; Joichl, Anea; Jungbauer, Karl; Kapl, Gerlinde; Kerschbaum, Margit; Kienesberger, Franz; Killinger, Gerhard; Kitzler, Gerhard; Klein, Franz; Kleinbichler, Dietmar; Kohr, Anton; Kopetzky, Michael; Korthals, Christian; Kortschak, Werner; Koschutnik, Martin; Kraus, Werner A.; Kurzemann, Susanne; Lavicka, Claus; Lehner, Guido; Lenz, Jürgen; Lepuschütz, Sabine; Lichtenwallner, Michael; Lober, Reinhard; Loidl, Christine; Lopatka, Eduard; Ludwig, Rudolf; Maca, Thomas; Mair, Anneliese; Mandak, Michael; Margreiter, Maria; Margreiter, Anea; Markovics, Michael; Matejicek, Frieich; Mohilla, Maximillian; Moll, Christian; Mörz, Beate; Mörz, Reinhard; Nagl, Heinz; Neumayr, Günther; Oberroitmair, Helmut; Oberzinner, Michael; Pallamar, Walter; Pangratz, Sibylle; Parandian, Laurenz; Paulus, Alexana; Pfaffenwimmer, Christoph; Plaichinger, Peter; Pokorn, Thomas; Polanec, Helmuth; Pöll-Weiss, Barbara; Pralea, Doralina; Puttinger, Johann; Quinton, Thomas; Ranegger, Matthias; Rass, Sepp; Rauch, Heribert; Riehs, Manfred; Robetin, Erich; Rohringer, Jörg; Rupprechter, Josef; Sadjed, Eduard; Schimbach, Johann Alois; Schmid, Jutta; Schneiderbauer, Rotraud; Schopper, Wolfgang; Schulze-Bauer, Alfred; Schuster, Gottfried; Schwarz, Johann; Schwarz, Maria; Schweighofer, Christoph; Schwelle, Franz; Simma, Hanspeter; Sock, Renate; Sock, Reinhard; Sprenger, Fritz; Stiglmayr, Thomas; Stocker, Ilse; Stütz, Pia; Tama, Mustafa; Teleky, Ursula; Tschauko, Werner; Veits, Martin; Vikydal, Gerhard; Vlaschitz, Karl; Wais, Elisabeth; Wais, Adam; Wegmann, Robert; Wehle, Franz; Weindl, Manfred; Weinhandl, Manuela; Wendt, Ursula; Wendt, Klaus; Werner-Tutschku, Volker; Werner-Tutschku, Christine; Wilscher, Josef; Wind, Norbert; Winter, Aneas; Wolfschütz, Gerald; Wolfsgruber, Markus; Wolfsgruber, Brigitte; Wurm, Renate; Ziebart-Schroth, Arno; Zimmermann, Maximillian; Zinnagl, Aneas; Zirm, Anea; Zirm Canada, Bernhard; Bokenfohr, Grace Mary; Liu, Edmond K. H.; Melling, Gordon W.; Papp, Edward William; Sachdeva, Ashok K.; Snyman, Ernst Retief; Varma, Sonya; Ward, Richard A.; Tiong Wong, Anew Pak; Basson, Paul J.; Brodie, Brian D.; Chahal, Sukhjiwan Jeevyn; Chan, William Y.; Chow, John C.; Cormack, Maura; Eddy, Donald H. J.; Ezekiel, Daniel; Farquhar, Anew; Gu, Shian; Hii, Ting H.; Ho-Asjoe, Marianne P. K.; Hosie, Anew; Jaffer, Shahin; Jakubowski, Anew T.; Karim, Mandy; Kiai, Cristina; Kooy, Jacobus; Lytle, Craig R.; Mcleod, Kevin Lain; Morgan, David C.; Myckatyn, Michael M.; Ng, John P. Y.; Schriemer, Ronnald; Schumacher, Gerhard; Grey Stopforth, James; Hoo Tsui, Winston Wai; Wilson, Robin T.; Wong, Danny; Wong, Wilfred T.; Yeung, Margaret M. W.; Cram, David Harvey; Kumari Dissanayake, Dilani Tamara; Gerber, Johan Daniel W.; Haligowski, David; Hrabarchuk, Blair; Kroczak, Tadeusz J.; Lipson, Alan H.; Mahay, Raj K.; Wessels Mare, Abraham Carel; Mohamdee, Feisal John; Olynyk, Frederick Theodore; Pieterse, Wickus; Ramgoolam, Rajenanath; Rothova, Anna; Saunders, Kevin Kenneth; Szajkowski, Stanley; van Gend, Richard F.; van Rensburg, Nicolaas Marthinus Jansen; Anand, Sanjiv; Baer, Carolyn E. H.; Basque, Eric J. Y.; Benaya, Sebastian; Bessoudo, Ricardo; Bhalla, Jaswinder; Chettiar, Nataraj V.; Craig, Brian N.; Desrosiers, France; Ranjani Imbulgoda, Manel; Morgan, Gareth M.; Nowak, Zbigniew J.; Scott, Daniel G.; Searles, Gregory R.; Slorach, J. Ninian; Stevenson, Robert N.; Browne, Noel John; Bruff, Karl Joseph; Collingwood, John Maurice; Collins, Wayne; Over, Aidan; Gabriel, Anthony M.; Govender, Moonsamy; Hart, David G.; Hatcher, Lydia B.; Janes, John; Kielty, John F.; Krisdaphongs, Michoke; Lush, Richard Boyd; Moulton, William Bertram; Riche, Cyril R.; Rideout, Gary M.; Roberts, Bernard C.; Walsh, Paul E.; Wight, Harold G.; Woodland, K. Heather; Woodland, Robert C.; Atkinson, Bradley Charles; Chow, Carlyle S. H. A.; Collins, James A.; Graham, Robert D.; Hosein, Jalal; Machel, Teresa M.; Mahaney, Gordon Ralston; Mclean, James Robert Bruce; Murray, Michael R.; Myatt, Gregory Alexander; Ozere, Christopher P.; Saha, Amal Krishna; Sanders, David Herbert; Seaman, Donald Maxwell; Seaman, James Gordon; Swinamer, Deanna; Voon Yee, Kenny Yew; Ali, Mohamed Mustapha; Bankay, Clarence D. C.; Beduhn, Eitel Erich Reinhold; Callaghan, Denis J.; Chan, Yun Kai; Chaudhri, Arif R.; Chen, Richard Y. Y.; Conway, James Robin; Cunningham, William L.; Cusimano, Steven Lawrence; Souza, Eleanor De; de Souza, Selwyn X.; Deyoung, John Paul; Epstein, Ralph; Faiers, Alan Arthur; Figurado, Victor John; Forbes, F. Basil Trayer; Gabor, Zsuzsanna; Gallardo, Rodolfo Canonizado; Gaur, Shiva K.; George, Elizabeth; Hartford, Brian J.; Shiu-Chung Ho, Michael; Ho, Chung; Ismail, Shiraz H.; Bhushan Kalra, Bharat; Koprowicz, Kinga; Kumar, Naresh; Lam, Clement; Lau, Ming-Jarm; Law, Hugo Kwok Cheung; Fung, Max Leung Sui; Liutkus, Joanne Frances; Lotfallah, Talaat K.; Luton, Robert G.; Meneses, Gloria S.; Miller, Mark Lee; Nagji, Noorbegum; Ng, Ken H. M.; Ng Thow Hing, Roland E.; Pandey, Amritanshu Shekhar; Petrov, Ivan; Rosenthall, Wendy; Rudner, Howard; Russell, Alan Douglas; Sanchez, Zenia A.; Shaban, Joseph A.; Shariff, Shiraz B. K.; Shih, Chung Ming; Sinclair, Duncan W.; Spink, Donald Richard; Tung, Tommy Hak Tsun; Vizel, Saul; Yanover, David Frederick; Zavodni, Louis S.; Cusack, Paul; Dewar, Charles M.; Hooley, Peter; Kassner, Rachel Anne; Mackinnon, Randy James; Molyneaux, Harold W.; Shetty, Karunakara Naduhithlu; Barrière, Ginette; Berjat, Maria B.; Bernucci, Bruno; Bérubé, Claude; Boueau, Ghyslain; Chehayeb, Raja; Ciricillo, Domenico; Constance, Christian M.; Côté, Gilles; Desroches, Jacques; Gagnon, Robert; Gaueau, Gilles; Godbout, Jean Louis; Harvey, Pierre; Hassan, Youssef; Hoang, Ngoc Vinh; Houde, Danielle; Lalonde, Alain-Paul; Lavoie, Régis; Leclair, Normand; Meagher, Luc; Ouimet, Alain; Plourde, Simon; Rioux, Denis W.; Roberge, Claude; Roy, Bruno; Sasseville, Richard; Serfaty, Samuel; Theriault, Lyne; Timothée, Jean R.; Tjia, Sabine; Tremblay, Bruno; Turcotte, Jean; Bose, Sabyasachi; Aletta Bouwer, Hester; Chernesky, Patricia A.; Johnson, Mervin Louis; Kemp, David R.; Lai, Raymond Pong-Che; Lee, Frank R.; Lipsett, William G. C.; Lombard, Schalk J.; Majid, Falah S.; Malan, Johannes J.; Maree, Narinda; Nayar, Arun; Nel, Mandi; Oduntan, Oluwole O.; Rajakumar, Alphonsus R. J.; Baraka Ramadan, Fauzi; Shamsuzzaman, Mohammed; Vermeulen, Abraham P. M.; Fred, C.; Anthonsen, Birgitte; Ardest, Steen Pennerup; Arnold-Larsen, Susanne Kajsa; Axelsen, Allan; Barfoed, Klaus; Birkler, Niels Erik; Blokkebak, Jens; Boserup, Jørgen; Kettrup Brassøe, Jens Ole; Chovanec, Martin; Lykke Christensen, Bendt; Christensen, Micael; Skjøth Christensen, Randi; Eidner, Per Olav; Eisbo, Jørn; Elsvor, Jan; Engmann, Ida Veng-Christensen; Eriksen, Rene Milling; Frederiksen, Thorkil; Frølund, Hanne Charlotte; Garne, Susanne; Giørtz, Agnete; Gregersen, Bettina; Halkier, Merete Lundbye; Hansen, Jens Georg; Harder, Jan; Jørgen, Hans; Henriksen, O.; Kirkeby Hoffmann, Michael; Holk, Erik; Hollensen, Jan; Jacobsen, Rune; Jakobsen, Lotte; Jensen, Christian; Jensen, Morten; Jensen, Vibeke; Jepsen, Peter; Johannsen, Jens Arne; Verner Johansen, Lars; Johansen, Ole Steen; Juul, Kristian; Jørgensen, Arvid Frank; Jørgensen, Peter; Jørgensen, Ulrik Miilmann; Kensmark, Lars; Kjellerup, Carsten; Kjaer, Ejner; Kjaersgaard, Morten; Klubien, Peter; Kolby, Peter; Korsgaard Thomsen, Kristian; Krebs, Peter; Kristiansen, Tom; Lyng, Flemming; Madsen, Natalia V.; Meyer-Christensen, Jesper; Mogensen, Ole; Mortensen, Finn; Nielsen, Lotta Marie; Nielsen, Per Schiwe; Nielsen, Søren Kjærem; Ommen, Henrik; Juhl Otte, Jens; Østergaard Paridon, Volle; Parm, Michael; Peampour, Kian; Petersen, Kirsten; Pilgaard, Peder Jensen; Poulsen, Svend Erik; Preisler, Thomas; Hast Prins, Søren Ulrik; Randløv, Annette; Rasmussen, Birgit Reindahl; Elmegaard Rasmussen, Peter; Rasmussen, Regnar; Roed, Søren Flemming; Sander, Kirsten Foltmar; Schmidt, Ejnar Ørum; Jørgen Schultz, Paul; Smidemann, Margit; Solgaard, Jørgen; Stripp, Tommy; Søderlund, Michael Rene M.; Søgaard, Henning; Søndergaard, Dorte E.; Sørensen, Birgitte H.; Sørensen, Gerhard Seth; Thøgersen, Niels; Toftdahl, Hans; Uggerhøj, Hanne; Uhrenholt, Bjarne; Veronika Ullisch, Eva; Valentiner-Branth, Christian; Vinberg, Jørgen; Vinter, Svend Aage; Vittrup, Preben; Winther-Pedersen, Niels; Wøldike, Anne Grete; Zederkof, Jørgen M.; Thue Østergaard, Merete; Abiven, Patrick; Abraham, Dominique; de Beaumais, Philippe Adam; Ado, Jean Pierre; Affres, Helene; Agache, Regis; Airault Leman, Anne Marie; Moussarih, Abdallah Al; Albaric, Christian; Allaouchiche, Thierry; Allignol, Christian; Ammor, Mohammed; Ammoun Bourdelas, Corinne; Amsallem, Luc; Anquez, Denis; Antonini, Jean Michel; Assuied, Virginia; Attia, Gerard; Audebert, Olivier; Audibert, Henri; Ayach, Claude; Bagdadlian, Serge; Bagni, Marina; Baillet, Jean; Ballivian Cardozo, Fernando; Baranes, Robert; Barbier, Patricia; Barousse, Francoise; Bas, Sylvie; Battaglia, Jean Marc; Baudonnat, Bruno; Bauple, Jean Louis; Domengetroy, Frederic Baylac; Beard, Thierry; Beaumier, Eric; Beaumont, Jean Francois; Baylac Domengetroy, Frederic; Beck, Christian; Behar, Michel; Behr, Bernard; Benady, Richard; Benghanem, Mohamed Mounir; Benichou, Herve; Bensoussan, Jean Marc; Bensussan, Pierre; Bercegeay, Pascal; Berneau, Jean Baptiste; Bertolotti, Alexane; Bertrand, Sylviane; Besson, Alain; Bezanson, Christophe; Bezier, Christophe; Bezzina, Remy; Bichon, Herve; Bickar, Pierre; Billot, Pierre; Billot Belmere, Marie Claude; Bisson, Francois; Blanc, Dominique; Bloch, Jean Luc; Bloch, Bernard; Blondin, Hyacinthe; Blot, Jacques; Bloud, Raymond; Blouin, Pascal; Boesch, Christophe; Boiteux, Jean Luc; Bonnafous, Pierre; Bonneau, Yanick; Bonnefoy, Laurent; Borg, Bernard; Borys, Jean Michel; Brunehaut Petaut, Myriam; Boschmans, Sabine; Said, Rami Bou; Bouallouche, Abderrahmane; Bouchet, Jacques; Bouchlaghem, Khaled; Boulen, Yvon; Bouline, Benoit; Bounekhla, Mohamed Salah; Bouquin, Vincent; Bourgeois, Marie Brigitte; Bourgois, Didier; Brandily, Christian; Brandt, Pierre; Branquart, Frederic; Breilh, Patrick; Brilleman, Fabrice; Brisson, Thierry; Brocard, Francis; Bruel, Pierre; Brun, Jean Pierre; Buisson, Jean Gabriel; Buisson Virmoux, Isabelle; Bur, Christian; Cabal Malville, Elodie; Cabantous, Serge; Cabrol, Pierre; Cagnoli Gromovoi, Sylviane; Caillaux, Bruno Xavier; Caillot, Didier; Canchon Ottaviani, Isabelle; Canu, Philippe; Caramella, Alexana; Caramella, Alexane; Cardaillac, Christian; Carrivale, Alain; Cartal, Jean Pierre; Cassany, Bernard; Cauon, Bernard; Causeret, Jean Marie; Caye, Philippe; Cayet, Jean Paul; Cazor, Gilles; Cesarini, Joel; Chakra, Georges; Chambeau, Bernadette; Chambon, Valerie; Chanas, Jack; Chapuzot, Patrick; Charon, Ane; Charpin, Eric; Charton, Frederic; Cheikel, Jean; Chemin, Philippe; Chennouf, Kamel; Chequel, Henri; Chevrier, Denis; Ciroux, Patrick; Cissou, Yves; Claeys, Jean Luc; Clariond, Yves; Classen, Olivier; Cloerec, Ane; Clouet, Sophie; Cloup Lefeuvre, Anne Marie; Cochet, Chantal; Cocuau, Didier; Cohen, Henri; Cohen Presberg, Pascale Cohen; Colin, Stephane; Colin, Remy; Colucci, Robert; Come, Philippe; Condouret, Pierre; Conturie, Agnes; Corbin, Ane; Corticelli, Paola; Coste, Daniel; Cotrel, Olivier; Coueau, Sylvie; Coulon, Paul; Courdy, Christian; Courtin, Marc; Courtot, Pierre; Coutrey, Laurent; Couval, Rene; Cravello, Patrick; Cressey, Olivier; Cuisinier, Yves; Cunin, Bernard; Cunnington, Bernard; Cusseau, Herve; Cuvelier, Christian; Arailh, Bruno D.; Dabboura, Adib; Dages, Laurence; Dahmani, Noureddine; Dandignac, Jean Christophe; Daney, Dominique; Dannel, Bernard; Darbois, Dominique; Dareths, Philippe; Daubin, Daniel; David, Jean Claude; de Foiard, Patrick; de Mallmann Guyot, Veronique De; de Wit, Marie Astrid; Debast, Francoise; Deboute, Eric; Debuc, Jean Pierre; Dechoux, Edouard; Decloux, Olivier; Decruyenaere, Yannick; Dejans, Jacques Maurice; Delarue, Michel; Delattre, Xavier; Delmaire, Patrick; Denis, Lucien; Deschamps Ben Ayed, Myriam; Devins, Pascal; Dezou, Sylvie; Dieuzaide, Pierre; Dirheimer, Bertrand; Dominguez, Paul; Donadille, Florence; Dondain, Benoit; Doridan, Pierre; Ouhet, Pascal; Dubois, Arnaud; Dubois, Ane; Ducharme, Pascal; Duchez, Paul; Dulard, Catherine; Dumoulin, Marc; Duprey, Georges; Durand, Jacques; Mohamed, Ibrahim; Chehab, El; Emery, Bernard; Emmanuel, Georges; Ashari, Ghazaleh Esna; Evrard, Eric; Fargeot Lamy, Aleth; Farges, Jean Louis; Faucher, Patrick; Faucie, Alain; Faure, Yves; Favre, Jean Jacques; Felipe, Jean Louis; Feret, Daniel; Ferragu, Alain; Ferrandin, Gerard; Ferriot, Francois; Finelle, Laurent; Flond, Jacques; Foieri, Jean; Fol, Stephane; Fontaine, Brigitte; Forichon, Dominique; Foucry, Michel; Fournier, Jean Francois; Fregeac, Bernard; Fuchs, Martin; Gabriel, Franck; Gaimard, Didier; Gallois, Stephane; Garapon, Georges; Garas, Mamdouh; Garcia, Pierre; Garcia, Jean Michel; Garcia, Marie Pierre; Garman, Waddah; Garzuel, Dominique; Gaspard, Jean Marc; Gauci, Laurent; Gautheron, Patrick; Gauthier, Jacques; Gauthier Lafaye, Pierre Yves; Gay, Michel Charles; Gay Duc, Bernadette; Gayout, Olivier; Gegu, Yann; Gentile, Francois; Germain, Emmanuel; Gharbi, Gerard; Gigandet Tamarelle, Catherine; Gilardie, Alain; Gilles Verliat, Martine; Gillet, Thierry; Gnana, Philippe; Goguey, Alain; Gombert, Alain; Gonin, Bernard; Gonzales, Philippe; Goulesque, Xavier; Graba, Jean Marc; Granier, Alain; Greiner, Olivier; Groboz, Martial; Gromoff, Serge; Grossemy, Xavier; Grossi, Christian; Guenin, Frederic; Gueranger, Pierre; Guerin, Patrick; Guerineau, Jean Pierre; Guessous Zghal, Fathia; Guicheux, Dominique; Guillere, Jacqueline; Guyonnet, Gilles; Haddad, Samir; Hadj, Nordine; Hamani, Djamel; Hamm, Jacky; Hammoudi, Djamal; Harle, Xavier; Harnie Coussau, Pierre; Hazen, Richard; Hembert, Francois; Hemon, Pierre; Hergue, Michel; Hestin, Christian; Heyraud, Luc; Hindennach, Dieter; Hirot, Etienne; Ho Wang Yin, Chan Shing; Hocquelet Denis, Catherine; Hoppe, Patrice; Horovitz, Daniel; Hours, Jean Michel; Houta, Benjamin; Hua, Gerard; Hui Bon Hoa, Nicole; Humez, Philippe; Hurier, Michel; Husson, Gerald; Hyvernat, Guy; Ichard, Jean Francois; Impens, Claude; Iovescu, Decebal; Jacob, Philippe; Jacob, Gildas; Jacquemart, Jean Pierre; Jacquier, Philippe; Jahanshahi Honorat, Shideh; Jalladeau, Jean Francois; Jan, Luc; Jannel, Yves; Jarrige, Vincent; Jeremiasz, Richard; Annick Jestin Depond, Marie; Joseph, Michel; Joseph Henri Fargue, Helene; Joubrel, Alain; Jouet, Alain; Julien, Bruno; Jullien, Francois; Jullien, Jean Louis; Kadoche, David; Kahl, Etienne; Kanawati, Aiman; Khalife, Sami; Khettou, Christophe; Kiers, Jean Paul; Kissel, Christian; Klein, Jean Claude; Klopfenstein, Samuel; Koch, Alexis; Koenig, Georges; Kohler, Philippe; Koriche, Abdelmalek; Labernardiere, Nicole; Labet, Philippe; Lablanche, Fabien; Laborde Laulhe, Vincent; Lagorce, Xavier; Laine, Eric; Lalague, Pascal; Laleu, Jean Noel; Lambert, Michel; Lambert Ledain, Mireille Lambert; Lambertyn, Xavier; Lame, Jean Francois; Langlois, Frederic; Lanoix, Eric; Laprade, Michel; Lasseri, Charaf; Laterrade, Bernard; Laurent, Jean Claude; Laurier, Bernard; Laval, Laurent; Le Borgne, Patrick; Le Franc, Pierre; Le Henaff, Patrick; Le Noir de Carlan, Herve; Le Roy, Jean Pierre; Le Roy Hennion, Florence; Lebon, Louis; Lecler, Olivier; Leclerc, Philippe; Ledieu, Christian; Lefebvre, Bernard; Lefevre, Philippe; Lehujeur, Catherine; Leiber, Christian; Leick, Gerard; Lemberthe, Thierry; Lenevez, Norbert; Lenoble, Patrick; Leriche, Philippe; Leroux, Eric; Leroy, Jean Michel; Leroy, Christian; Lescaillez, Dominique; Leurele, Christian; Lhermann, Sophie; Libermann, Pierre; Licari, Gilbert; Lo Re, Antoine; Long, Philippe; Long, Jean Louis; Lormeau, Boris; Louchart, Jean Christophe; Lucas, Jean Pierre; Luquet, Thierry; Lussato, Philippe; Maarouf, Moustapha; Mabilais, Francois; Magnier Sinclair, Christine; Mahot Moreau, Pascale; Malafosse, Denis; Mandirac, Jean Paul; Manolis, Jerome; Mante, Jean Pierre; Maquaire, Claude; Marchal, Thierry; Marchand, Guillaume; Marillesse, Olivier; Marmier, Gabriel; Herve Maron, Yves; Marrachelli, Nadine; Marsaux, Michel; Martin, Bruno; Martin, Michel; Deiss, Pascale Martin; Masson, Arnaud; Mativa, Bruno; Matton, Jean Francois; Mauffrey, Jean; Mauriere, Serge; Maurois, Georges; Maury, Joceline; Mayer, Frederic; Menu, Pierre; Mercier, Bernard; Messmer, Daniel; Mestiri, Sami; Meyer, Gilles; Michaelides, Michael; Michaud, Gilles; Michenaud, Bernard; Mielot, Stephane; Millory Marco, Jerry Anne; Mingam, Stephane; Mira, Reginald; Mius, Stephane; Monnier Meteau, Marie Paule; Mora, Francis; Morbois Trabut, Louise; Morosi, Laurent; Mougeolle, Jean Luc; Mouget, Jean Louis; Mouroux, Daniel; Mouthon, Jean Marie; Muller, Jacques; Nakache, Ane; Narbonne, Herve; Navarranne Roumec, Anne; Navarro, Pierre; Neubrand, Jean Yves; Nguyen, Quang Thieu; Nguyen Quang, Guy; Nguyen Xuan, Thong; Niot, Patrice; Oudart, Jean Maurice; Outteryck, Alain; Pages, Jean Marie; Paillet, Charles; Pain, Jean Marie; Pangaud de Gouville, Patricia; Paquin, Olivier; Parent, Vincent; Parer Richard, Claire; Parrot, Francine; Parthenay, Pascal; Pascariello, Jean Claude; Passebon, Jean Claude; Pere, Alain; Perelstein, Laurent; Perot, Michel; Petit, Richard; Petit, Philippe; Petit, Francois; Petruzzi, Philippe; Phelipeau, Denis; Philippon, Jean Claude; Philippon, Gilles; Picard, Bruno; Picard, Jean Claude; Picot, Bernard; Piera, Jean Francois; Pieri, Alain; Piffoux, Eric; Pilard, Patrick; Pillet, Alain; Pinot, Philippe; Pinzani, Alain; Pleskof, Alain; Plessier, Jean Claude; Plisson, Alain; Pochon, Claude; Poggi, Valerie; Poirat, Alain; Poiree, Maurice; Polleux, Janick; Noel Pontecaille, Jean; Posocco, Regis; Pospiech, Jean Claude; Pradies, Felix; Prevot, Remi; Pueyo, Jean Bernard; Quaelli, Jacques; Rabbia, Michel; Rabemananjara, Aimery; Rami, Saad; Rapin, Jean Jacques; Rasquin, Corinne; Ratinaud, Didier; Reboud, Bruno; Reboul, Philippe; Reichman, Jean Jacques; Reinhardt, Patrick; Renard Houta, Catherine Renard; Reverdy, Olivier; Revol, Michel; Rey, Pierre Alain; Richardeau, Yves; Rives, Bernard; Robida, Christine; Rochez Fraiberg, Muriel; Rodet, Jean Pierre; Rolland, Jean Francois; Romand, Bruno; Romano, Jean Paul; Rosati Gretere, Chantal; Rosey, Alain; Rosset, Martial; Rossi, Jean Pierre; Rouquette, Georges; Rousseau, Michel; Rousselon, Xavier; Roy, Christophe; Royer, Denis; Ruetsch, Marcel; Saade, Maurice; Saby Kuchler, Nicolas; Samar, Guy; Sanchez, Pierre Yves; Sane, Alain; Sanz, Jean Paul; Sardon, Michel; Sarrazin, Marc Eric; Sasportes, Gilbert; Saudou, Francis; Sauze, Elisabeth; Savary, Pascal; Schenowitz, Alain; Schmartz, Pierre; Schoepfer, Marc Olivier; Seewagen, Jacques; Serramoune, Denis; Serre, Christian; Sicard Guroo, Helene; Sichãc, Jean Philippe; Sifaoui, Sylvain; Simoncello, Marc; Simonin, Marie Jeanne; Simonnet, Jean Francois; Spindler, Didier; Steier, Alain; Sultan, Charles Raphael; Taghipour, Kouroch; Talayrach, Bruno; Talbot, Francois; Talhouarn, Vanessa; Tallec, Yves; Tarasco Schenrey, Elisabeth; Tarrene, Michel; Tater, Dominique; Tessier, Bernard; Teste, Marie; Thierry, Dominique; Thiollier, Patrice; Thoreau, Frederic; Thual, Jean; Traen, Vincent; Trigano, Jacques Alexane; Troussier, Jean Bernard; Truong Ky Minh, Bernard; van Melckebeke, Gerard; Vaque, Philippe; Vaucelle, Celine; Vedel, Eric; Venu, Didier; Verdavoine, Patrick; Vergeron, Jean; Viallon, Philippe; Viault, Dominique; Vieules, Jean Max; Vigier, Jean Paul; Vilain, Jean Marie; Villard, Bruno; Vitoux, Jean Francois; Viviand, Paul; Vivien, Olivier; Walter, Patrice; Waquier, Patrick; Waszkiewicz, Jean Marc; Weidich, Stephane; Westerfeld, Raymond; Weynachter, Gerald; Wilhelm, Pierre; Wolff, Claude; Wursthorn, Marc; Zammattio, Didier; Zylinski, Bernard; Lauer, Peter; Kühn, Uwe; Weltzel, Wolfgang; Mohr, Hella; Weyland, Klaus; Spittel, Bärbel; Böhm, Günter; Ferdowsy, Said; Hanusch, Peter; Spiekermann, Josef; Albert, Edwin; Stuff, Karl; Jungmair, Wolfgang; Koller, Sabine; Schubert, Wilhelm; Schlehahn, Fred; Bormann, Gundula; Graf, Kristof; Stiehler, Gisela; Bock, Manfred; Müller, Angelika; Haufe, Michael; Nielsen, Lorenz; Raum, Doris; Rogler, Karin; Bürstner, Joachim; Völk, Hans-Jörg; Sachse, Michael; Escher, Torsten; Doumit, Adel; O'dey, Hildegard; Holzmann, Ulrike; Sauer, Hermann; Schellenberg, Gottfried; Carius, Jürgen; Dänschel, Wilfried; Kopf, Aneas; Zerr, Elena; Tatalovic, Ratko; Rupp, Heiun; Anders, Elfriede; Mende, Marion; Volk, Ulrich; Hagenow, Aneas; Lang, Thomas; Schmitz, Karl-Heinz; Gössling, Jan-Henik; Mutsch, Günther; Steidel, Joachim; Osten, Klaus; Giokoglu, Kiriakos; Bellisch, Sabine; Füll, Katja; Walther, Wolfgang; Flick, Sabine; Dünnebier, Rosemarie; Dharmawan, Ichsan; Schönmehl, Wolfgang; Hoss, Valentin; Kipping, Stephan; Wolf, Hans-Joachim; Wolf, Hans-Frieich; Willmann, Volker; Bugarski, Bruno; Hoffschröer, Josef; Von Wallfeld, Siegrun; Ruhland, Guun; Bulling, Daniel; Häusler, Maren; Haustein, Gabriele; Kallenbach, Cornelia; Schwemmler, Claudia; Frank, Antje; Lodder-Bender, Ulrike; Rawe, Klaus; Reinert, Hans-Ferdinand; Schönhof, Petra; Fahrenschon, Klaus; Schorcht, Elisabeth; Etzold, Erika; Brehm, Michael; Paust, Wolf-Dieter; Schulte-Kemna, Achim; Pötter, Klaus-Werner; Ott-Voigtländer, Ulrike; Schwenke, Reto; Thinesse-Mallwitz, Manuela; Siml, Steffi; Stern, Hirene; Roelen, Harald; Scherhag, Klaus-Peter; Matulla, Petra; Herrmann, Hans Joachim; Neumann, Gerhard; Barbuia, Marius; Vormann, Reinhold; Hitzler, Karl; Linum, Aneas; Hanke, Klaus; Hohberg, Hans-Joachim; Klingel, Roger; Hohnstädter, Rainer; Klasen, Hartmut; Aschermann, Peter; Grau, Wilfried; Killinger, Paul; Gross, Kathrin; Naus, Rainer; Todoroff, Karin; Zühlke, Wolfgang; Kellner, Hanns-Ulrich; Hager, Eva; Thieme, Jochen; Kornitzky, Michael; Rösch, Volker; Heinze, Elke; Hiederer, Wolfgang; Konz, Karl-Heinz; Köhler, Michael; Diekmann, Martin; Junghans, Edith; Dietermann, Friedgard; Kerp, Ekkehard; Schäfer-Lehnhausen, Silvia; Kruck, Irmtraut; Ettelt, Rolf; Hölscher, Aneas; Kittler, Sybil; Jung, Heiun; Mailänder, Albert; Nowara, Peter; Ritschl, Harald; Mödl, Bernhard; Gallwitz, Torsten; Meyer, Stephan; Peter, Anton; Peters, Otto; Pflaum, Petra; Fröhlich, Karl-Heinz; Mertens, Hans-Jürgen; Merlin-Sprünken, Verena; Erpenbach, Klaus; Fervers, Frank; Kuhl, Ulrike; Halsig, Friedemann; Rein, Wilfried; Hauser, Ernst-Richard; Laubenthal, Florin; Richard, Frank; Langer, Claus; Lange, Rainer; Eska, Jan; Mohanty, George; Lange, Isengard; Eltges, Nicole; Kuntz, Christoph; Mechery, Thomas; Vöckl, Josef; Viergutz, Christoph; Stähle-Klose, Claudia; Sohr, Katja; Böhler, Steffen; Brecke, Georg; Burls, Malcolm; Werner, Karl-Michael; Vorpahl, Ralf; Stahl-Weigert, Beate; Bunge, Gerd; Thomsen, Jutta; Blessing, Erwin; Bengel, Bengel; Buhlmann, Ulla; Tröger, Tröger; Sippel, Sippel; Vossschulte, Vossschulte; Wilms, Wilms; Appelt, Appelt; Dauterstedt, Dauterstedt; Witte, Witte; Böttger, Uta; Wyborski, Waltraud; Strache, Sabine; Böttger, Werner; Zeiner, Luise; Wuttke, Wanda; Stoidner- Amann, Annette; Stoermer, Brigitte; Bock, Stephan; Groos-März, Cornelia; Thamm, Maria-Elisabeth; Meier, Josef; Schneider, Martin; Niessen, Ulrich; Storm, Gernot-Rainer; Streitbürger, Elmar; Münkel, Thomas; Palfi, Mihai; Naumann, Ulrich; Tannhof, Gabriele; Streibhardt, Frank; Gebhardt, Wolfgang; Nieswandt, Gerhard; Gerke, Ulrich; Nöhring, Axel; Bott, Jochen; Goertz, Jutta; Winkler, Dietmar; Lotter, Edith; Kraaz, Katja; Bärwinkel, Petra; Hildebrandt, Diana; Weyers, Georg; Kubin-Siring, Birgit; Baier, Eduard; Weber, Thomas; Holz, Dirk-Egbert; Wolfers, Johannes; Kihm, Wolfgang; Kamali-Ernst, Schirin; Amann, Wolfgang; Kaase, Hans-Jürgen; Banning, Ottmar; Voigt, Thomas; Grünert, Frank; Gürtler, Michael; Pferdmenges, Karin; van Treek, Heiko; Möller, Bernd; Weigel, Sybille; Jun Hassler, Normann; Mauer, Helmuth; Beckers, Erwin; Weber, Clemens-August; Hawash, Hana; Ladke, Dietrich; Labitzky, Gerlinde; Kunkel, Petra; Hartung, Wolfgang; Pomykaj, Thomas; Prokop, Heiun; Schleif, Thomas; Cascino, Luisa; Exner, Petra; Daelman, Eric; Dietrich, Aneas; Prasse, Thomas; Brundisch, Stefanie; Schipper, Ralf; Duderstaedt, Bernd; de Haan, Fokko; Schmidt-Reinwald, Astrid; Seidel, Peter; Schmitz, Joachim; Bülent, Ergec; Ja Pique, Pyoong; Ding, Roland; Eggeling, Thomas; Duderstaedt, Elvira; Ferchland, Hans-Peter; Kruth, Renate; Gralla, Dieter; Köhler, Angelika; Laborge, Joachim Rene; Hammer, Harald; Richter, Ilona; Sauldie, Happy; Valk-Denkema, Inge Van Der; van der Valk, Leo; Feely, John; Dunne, Liam; Cox, John; Doyle, Michael; O'Gorman, Mary; Kennedy, John; Maher, Brian; Forde, Derek; Harrington, Peter; Cronin, Brian; Coady, Anew; Craig, John; O'Dowd, Caroline; O'Doherty, Brian; O'Connor, Patrick; Ling, Roland; Perry, Majella; Crowley, James; Keaveney, Lynda; Townley, Eadaoin; O'Shea, Eamonn; Regan, Michael; Cunningham, Seamus; Bluett, Desmond; Whyte, Oliver; Casey, Michael; Ruane, Fergal; Fitzgerald, Eleanor; O'Beirn, Eugene; Faller, Eamonn; Moffatt, Sean; Coleman, Michael; Day, Brendan; Mcadam, Brendan; O'Neill, Daragh; Mac Mahon, Conor; Wheeler, Mark; Byrne, Sheila; Fulcher, Kieran; CAREY, Owen; O'Connell, Kieran; Keane, Jack; Almarsomi, Laith; Vaughan, Carl; O'Callaghan, Tom; Grufferty, Tadgh; Shanahan, Eamon; Crowley, Brendan; Moran, Joe; Cotter, Jeremy; Healy, Colin; Curtin, Tom; Dillon, Joe; Dennehy, Thomas; Murphy, Elaine; Kennedy, Michael; Coffey, Donal; Carroll, Paul O.; Oliver, Barry; Mccarthy, Shane; Joyce, Peter; O'Shea, Gerard; Apperloo, A. J.; Basart, D. C. G.; Bax, M.; Beysens, P. A. J.; Breed, J. G. S.; Derks, A.; Eijgenraam, J. W.; Hermann, J. P. R.; Janus, C. L.; Kaasjager, H. A. H.; Klomps, H. C.; Koole, M. A. C.; Koster, T.; Kroon, C.; Lieverse, A. G.; Massaar-Hagen, B. E. M.; Moghaddam, F.; Oldenburg-Ligtenberg, P. C.; Potter van Loon, B. J.; Stroes, E. S. G.; Twickler, Th B.; van Asperdt, F. G. M. H.; van Asseldonk, J. P. M.; van der Loos, T. L. J. M.; van der Velde, R. Y.; van der Vring, J. A. F.; van Dorp, W. T.; van Essen, G. G.; van Kalmthout, P. M.; van Liebergen, R. A. M.; van Wissem, S.; Waanders, H.; Withagen, A. J. A. M.; Andersen, Per Vidar Klemet; Andersen, Randi F.; Andersson, Egil; Arnstad, Asle; Belguendouz, Larbi; Birkeland, Inge Arve; Bjørkum, Kari; Bredvold, Thor; Brevig, Leif Harald; Buchman, Erik; Burkeland-Matre, Rune; Burski, Krzysztoft; Byre, Roald; Bø, Per Erik; Dahl, Erik; Duch, Anna; Duong, Khoa; Dvergsdal, Peter; Edvardsen, Magne; Ernø, Asbjørn; Fredwall, Svein Otto; Glasø, Morten; Glasø, Jan; Grini, Asbjørn; Hallaråker, Arne; Normann Hansen, Age Normann; Haugland, Helge Haugland; Henrichsen, Svein Høegh; Hestnes, Atle; Idehen, Norman I. E.; Jacobsen, Kristin Løland; Johansen, Ture; Johnsen, Roald; Jonasmo, Kåre; Kirknes, Svetalana; Kjetså, Arild; Kjaer, Peter; Knoph, Erik; Knutssøn, Carl; Koss, Arne; Kravtchenko, Oleg; Krogsæter, Dagfinn; Langaker, Kåre; Lind, Knut W.; Lund, Kjell Rømyhr; Madsbu, Sverre; Mehlum, Yvonne E. Mazurek; Moon, Philipp; Movafagh, Aram; Myhrer, Kurt; Nørager, Dan Michael; Ore, Stephan; Rafat, Hooshang B.; Rød, Reinert; Schmidt-Melbye, Torgeir; Singh, Navneet; Singsås, Tore; Skjelvan, Gunnar; Smet, Arthur; Staalesen, Staale; Storeheier, Espen; Storhaug, Sidsel; Storm-Larsen, Ane; Sundby, Jon Eivind; Syverstad, Dag Eivind; Sørensen, Anne Sissel; Torjusen, Trygve B.; Torkelsen, Arne; Tunby, Jan Reidar; Vanberg, Pål Johan; Vevatne, Audun; Vikse, Arild; Wahlstrøm, Viktor; Walaas, Kirsten; Walløe, Arne Eyolf; Wear-Hansen, Hans-Gunnar; Ole Ystgaard, Ole Aneas; Zimmermann, Birgit; Øvsthus, Knut; Aião, Julio; Albuquerque, Mario; Alves, Fernando; Esteves, Antonio; Amaral, Maria Fatima; Amaral, Fátima; Amorim, Helena; Anade, Benilde; Anade, Maria Benilde; Antonio, Godinho; Araujo, Francisco; Arriaga, Antonio; Baeta, Sonia; Afonso, Francisca Banha; Beato, Vitor; Beirão, Paula; Martins, Ausenda Belo; Bernardes, Jose; Botas, Luis; Baeta, Antonio; Ramos, Manuel Braga; Brandão, Peo; Brandão, Antonio G.; Brandão, Antonio; Raposo, Antonio Caetano; Carrilho, Francisco; Carvalho, Isabel; Carvalho, Patricia; Castel-Branco, Ana; Castellano, Maria Desamparados; Corredoura, Ana; Corredoura, Ana Sofia; Costa, Vitor; Coutinho, João; Crujo, Francisco; Cunha, Damião; Dias, Manuela; Fernandes, Maria Emilia; Ferreira, Gustavo; Ferreira, Dirce; Ferreira, Jorge; Ferreira, Antonio M.; Fonseca, Antonio; Freitas, Paula; Gago, Amandio; Galego, Rosa; Garrett, Antonio Viriato; Gavina, Cristina; Simões, José Geraldes; Gomes, Maria Fatima; Gomes, Norberto; Gomez, Brigitte; Graça, Peo; Gravato, Antonio; Guedes, Nuno Filipe; Guerra, Fernanda; Issa, Custódio; João, Isabel Fernandes; João, Isabel; Jorge, Vasco; Leite, Maria Salome; Lousada, Nuno; Macedo, Filipe M.; Madeira Lopes, João; Magalhães, Jorge; Marinho, Jose Carlos; Marques, Carlos; Marques, Jose Augusto; Marques Ferreira, Antonio; Martins, Jose Carlos; Martins, J. Belo; Matos, Alice; Melo, Miguel; Miguel, Antonia; Monteiro, Filomena; Monteiro, Francisco; Monteiro, Filomena B.; Sarmento, João Morais; Morato Sá, Maria José; Mota, Joana; Moura, Luis; Moura, Brenda; Neves, Lena; Neves, Celestino; Oliveira, Maria; Oliveira Ramos, Manuel; Osorio, Ramos; Pacheco, Joao; Palma, Isabel; Peixoto, Maria Cristina; Pereira, Helder; Pestana, João; Pignatelli, Duarte; Pinho, Hernani; Puig, Jorge; Raindo, Maria; Ramos, Helena; Rebelo, Marta; Roigues, Antonio; Roigues, Alvaro; Roigues, Elisabete; Rola, José; Rovytchcva, Milena; Sa, João; Santos, Fernando; Santos, João Cesar; Sequeira Duarte, Joao; Serra E Silva, Polybio; Silva, Bernardino; Silva, Paula; Silva, Maria; Silva, Francisco; Silva, Dora; Silva, José; Silvestre, Isabel; Simões, Heleno; Soares, Manuela; Sousa, Nelson; Sousa, Antonio; Souto, Delfina; Teixeira, Esmeralda; Torres, Isabel; Valle, Tahydi; Ventura, Carlos; Vicente, Ana; Vieira, Muriel; Alfaro, Rafael; Alonso, Roigo; Alvarez, Juan Carlos; Allut, Germán; Amado, Jose A.; Ampuero, Javier; Angel, Luis Fernando; Antolín, Eduardo; Anton, Javier; Aranda, Jose Luis; Argimon, Jordi; Arques, Francesc; Arribas, Jose Peo; Arroya, Concepción; Arroyo, Jose Antonio; Auladell, Maria Antonia; Bajo, Julian; BALVIN, Alberto; Ballester, Jose Vicente; Barreda Glez, Maria Jesus; Becerra, Antonio; Bermejo, Juan Carlos; Bernacer, Luis; Besada, Ricardo; Blasco, Jesús; Bravo, Manuel; Bueno, Francisco Manuel; Campo, Ignacio; Carrasco, Jose Luis; Catalán, José Ignacio; Cobo, Jose; Coello, Ignacio; Combarro, Jesús; Contreras, Juan A.; Correa, Julian; Cortilla, Alberto; Cuatrecasas, Guillem; Chicharro, Sana; de Dios, Juan; de Los Arcos, Enrique; de Portugal, Jose; del Cañizo, Francisco; del Molino, Fatima; Díaz, Jose Luis; Domingo, Javier; Escobar, Carlos; Escoda, Jaume; Espinosa, Eugenio; Ester, Francisco; Fernandez, Antonio; Ferreiro, Manuel; Fondas, Jose Maria; Fraile, Angel Luis; Franco, Miguel; Fuentes, Francisco; Garcia, Jose Antonio; Garcia, Domingo; Garcia, Manuel Enrique; García, Luis; Garcia, Jesus; Gilabert, Rosa; Goiria, Begoña; Gomez, Purificación; Gomez-Calcerrada, David; Gonzalez, Manuel; Gonzalez, Jose Manuel; Guijarro, Carlos; Guirao Gujarro, Victor; Herrera, Carlos; Herrera, Maria Carmen; Herrero, Miguel; Ibarguren, Amaya; Irigoyen, Luis; Jimenez, Blas; Lamelas, Jose Antonio; Laplaza, Ismael; Laporta, Felix; Lazo, Victor; Leal, Mariano; Ledesma, Vicente; Lopez, Peo; Lopez, Pablo; Lopez, Alberto; López, Maria Jose; Lopez-Cepero, Eduardo; Lorenzo, Francisco; Lucena, Javier; Luquín, Rafael; Lloveras, Ariadna; Maceda, Teresa; Macia, Ramon; Marti, Cristina; Martin, Jose Maria; Martin, Isodoro; Martín Lesende, Iñaki; Martinez, Mercedes; Martinez, Juan Alberto; Martinez, Peo; Martinez, Angel; Mato, Fernando; Medel, Federico; Mederos, Ana Maria; Mediavilla, Javier; Mediavilla, Gregorio; Mestron, Antonio; Michans, Antonio; Millán, Jesús; Molina, Carlos; Monroy, Carmelo; Monte, Inés; Montes, Jose Maria; Morales, Clotilde; Morales, Francisco J.; Morata, Carmen; Mori, Carlos; Muñoz, Jaime; Muñoz, Maria Jose; Núnez, Julio; Nuñez, Alfonso; Ocaña, Fermin; Olaz, Fernando; Ollero Artigas, Anes; Ortega, Juan; Oteo, Olga; Pascual, Jose Maria; Paya, Jose Antonio; Pechuan, Joaquín; Penedo Suarez, Ramón; Perez, Eugenia; Pesquera, Carlos; Pia, Gonzalo; Piea, Maria; Pinilla, Martin; Pita, Alejano; Pose, Antonio; Prieto Díaz, Miguel Angel; Quesada, Carmen; Ramirez, Francisco; Ramirez, Carmen; Ramirez, Luisa; Reinares, Leonardo; Rey, Salvador; Ribas, Montse; Ridaura, Amparo; Ridocci, Francisco; Rigueiro, Peo; Rivera, Salomón; Robles, Antonio; Rodero, Estrella; Roiguez, Jose Angel; Romero, Fernando; Romero Hernandez, Franklin; Romeu, Regina; Rubio Buisán, Lorenzo; Salas, Fernando; Sánchez, Carlos; Sánchez, Jesus; Saponi, Jose Maria; Serres, Miguel; Suarez, Saturnino; Suarez, Carmen; Tato, Maria; Tebar, Francisco Javier; Toda, Maria Roca; Tofe, Santiago; Urdiain, Raquel; Vaamonde, Leopoldo; Valderrama, Javier; Vazquez, Jose Antonio; Velazquez, Osvaldo; Venell, Federico; Vilariño, Ruben; Villa, Maria Jesus; Villar, Maria Dolores; Zarauza, Jesus; Zuñiga, Manuel; Abab, Jose Luis; Abad, Eduardo; Abad, Rafael; Afonso, Carmen; Aguilar, Gerardo; Alberiche, Maria Del Pino; Alcolea, Rosa; Alegria, Eduardo; Almagro, Fátima; Almenara, Africa; Almenos, Maria Cruz; Alonso, Javier; Alvarez, Manuel; Ampudia, Javier; Andia, Victor Manuel; Anglada, Jordi; Aranda, Miguel Ángel; Arbelo, Lorenzo; Armengol, Francesc; Arnau, Asunción; Arrarte, Vicente; Arribas, Bienvenido; Artiñano, Yolanda; Avilés, Benjamín; Ayensa, Javier; Ballestar, Enric; Ballester, Javier; Barcelo, Bartolome; Barcena, Felix; Barranco, Mercedes; Barrena, Isabel; Barriales, Vicente; Barrot, Joan; Bartolome, Jose A.; Belmonte, Joan; Bellés, Amadeo; Benito, Josefina; Bernad, Antonio; Biendicho, Armando; Blanco, Rubén; Boix, Evangelina; Bonora, Carlos; Boxó, Jose Ramon; Brea, Angel; Caballero, Peo; Cabrera, Peo; Cabrero, Juan Jose; Calduch, Lourdes; Calero, Francisco; Calvo Garcia, Jose Javier; Camacho, Jose; Canales, Juan Jose; Caparros, Jorge; Carbonell, Francisco; Caro, Manuel; Castilla, Miguel Angel; Castillo, Luis; Cepero, Daniel; Cerdan, Miguel; Cimbora, Antonio; Civera, Miguel; Colchero, Justo; Comas Fuentes, Angel; Corpas, Clara; Corrales, Juan Antonio; Cotobal, Eusebio; Cruz, Carmen; Cruz, Inmaculada; de La Flor, Manuel D.; de Luis, Alberto; del Alamo, Alberto; del Rosario, Victor; Diego, Carlos; D'Lacoste, Marta; Doganis Peppas, Constantino; Dominguez, Jose Ramon; Durá, Francisco Javier; Durand, Jose L.; Ena, Javier; Encinas, Ana Rosa; Erdozain, Juan Peo; Escribano, Jose; Escriva, Blanca; Esteve, Eduardo; Facila, Lorenzo; Fenoll, Federico; Fernandez, Eugenio; Fernandez, Celia; Fernandez, Maria Jesus; Fernandez, Antonia; Fernandez, Jacinto; Fernandez, Severo; Fernandez, Jose Manuel; Fernandez, Jose Manuel Fernandez; Ferrer, Juan Carlos; Ferrer, Peo; Ferrer Bascuñana, Peo; Fierro, Maria Jose; Flores, Julio; Fuentes, Fernando; Fuertes, Jorge; Galgo, Alberto; Galvez, Angel; Gallego, Anea; Garcia, Maria Angeles; Garcia, Jose; Garcia, Maria Luisa; Garcia, Peo; Garcia, Javier; García, Francisco; Garrido, Nícolas Garrido; Gil, Manuel Gil; Ginés Gascón, Ramón; Godoy, Diego; Gomez, Carlos Manuel; Gonzalez, Miguel; Gonzalez, Rosa; Gonzalez, Rocío; Gonzalez, Enrique; Gonzalez, Juan Jose; Gonzalez, Joaquin; Gonzalez Huambos, Adan; Guerrero, Jordi; Guillen, Rosario; Guirao, Lorenzo; Gutierrez, Fernando; Gutierrez, Diego; Hernandez, Alberto; Hernandez, Antonio; Hernandis, Vicenta; Herrero, Jose Vicente; Herreros, Benjamin; Hevia Roiguez, Eduardo; Horgue, Antonio; Illan, Fatima; Inigo, Pilar; Ibrahim Jaber, Ali; Jimenez, Manuel; Jornet, Agusti; Juanola, Ester; Laguna, Alfonso; Latorre, Juan; Lebron, Jose Antonio; Lecube, Albert; Ledesma, Claudio; Ligorria, Cristina; Lima, Joan; López, Jose Enrique; Lopez, Manuel; López, José Antonio; López, Jaime; López, Isio; Lozano, Jose Vicente; Mangas, Miguel Angel; Mangas, Alipio; Manzano, Antonio; Maraver, Juan; Marco, Maria Dolores; Marchán, Enrique; Marchante, Francisco; Marin, Fernando; Marreo, Josefa Esther; Martin, Manuel; Martin, Alberto; Martin, Francisco Javier; Martinez, Antonio; Martinez, Guillermo; Martínez, Luis; Martinez Barselo, Antonio Pablo; Mas, Emili; Mascareño, Isabel; Mascarós, Enrique; Massa, Rita; Mazón, Pilar; Mediavilla, Juan Diego; Mena, Candido; Mendez, Jose; Mendez, Jose Maria; Mezquita Raya, Peo; Millan, Jose Maria; Millaruelo, Jose; Minguela, Ester; Miret, Pere; Molina, Mariano; Molina, Carmen; Montagud, Blanca; Montalban, Coral; Montiel, Angel; Montoro, Javier; Monze, Bernardo; Moreno, Francisco Luis; Morillas, Antonio; Moro, Jose Antonio; Moya, Ana; Muñiz, Ovidio; Muñoz, Manuel; Navarro, Vicente Luis; Nerin, Jesus; Nicolas, Ricardo; Nogueiras, Concepción; Ojeda, Benito; Olmerilla, Javier; Oller, Guillermo; Ortega, Antonio; Ortega, Manuel; Ortega, Miguel; Ortiz, Maria Jose; Otegui Alarduya, Luis; Palet, Jordi; Palomo, Jesus; Paytubí, Carlos; Peiro, Rafael; Pelaez, Carmen; Peña, Peo; Peñafiel, Javier; Perez, Antonia; Perez, Elvira; Perez, Tomas; Peso, Miguel; Pilar, Juan Manuel; Piñeiro, Carlos; Plaza, Jose Antonio; Polo, Noelia; Portal, Maria; Prieto, Jesus; Prieto, Luis; Prieto Novo, Manuel; Puñal, Peo; Quesada, Miguel; Quindimil, Jose Antonio; Rabade, Jose Manuel; Ramila Beraza, Luis Antonio; Ramirez, José Manuel; Ramos, Jose Antonio; Ramos, Francisco; Rayo, Manuel; Reixa Vizoso, Sol; Reyes, Antonio; Rico, Miguel Angel; Ripoll, Tomas; Rivera, Antonio; Robres, Mariano; Rodilla, Enrique; Roiguez, Miguel Angel; Roiguez, Zoilo Jesus; Roiguez, Carlos; Roiguez, Pilar; Roiguez, Melchor; Roiguez, Alfonso; Rojas, Domingo; Rosell, Luis; Rossignoli, Carlos; Rueda, Antonio; Rueda, Eloy; Ruix, Anes; Ruiz, Jose Antonio; Ruiz, Luis; Saban, Jose; Saez, Francisco Jose; Salleras, Narcis; Sánchez, Gerardo; Sanchez, Gloria; Sanchez, Angel; Sanfeliu, Josep Maria; Sangros Gonzalez, Javier; Santos, Francisco; Santus, Eufrosina; Sebastian, Alfredo; Seguro, Maria Eugenia; Selles, David; Serrano, Daniel; Serrano, Soledad; Serrano, Adalberto; Sestorain, Francisco; Solbes, Ruben; Soriano, Cristina; Suárez, Héctor; Surroca, Maria Luisa; Tarabini, Ada; Tarraga, Peo; Teixido, Eulalia; Terron, Raquel; Torres, Antonio; Tortosa, Jose Maria; Tortosa, Frederic; Valdés, Carmen; Valdés, Peo; Valiente, Jose Ignacio; Varo, Antonio; Vazquez, Enrique; Vázquez, Luis; Vela Ruiz de Morales, Jose Manuel; Vericat, Antonio; Vicioso, Peo; Vilaplana, Carlos; Villazón, Francisco; Lidia Viñas, Lidia Viñas; Zuagoitia, Jose Felix; Nörgaard, Faris; Dziamski, Ryszard; Haglund, Lars; Holm, Daniela; Sars, Mikael; Jagunic, Ivica; Östgård, Per; Kumlin, Lars; Jacobsson, Michael; Hamad, Yousef; Jäger, Wanje; Särhammar, Lars; Olsson, Anders; Boldt-Christmas, Antonina; Nyborg, Karin; Kjellström, Thomas; Ghazal, Faris; Wikström, Lene; Holby, Torulf; Bhiladvala, Pallonji; Kynde, Sara Maria; Eizyk, Enrique Julio; Tengblad, Anders; Christoffersson, Ole; Sjöström, Astrid; Kynde, Christian; Katzman, Per; Tenhunen, Anita; Lennermo, Klas; Lindholm, Carl-Johan; Löndahl, Magnus; Elfstrand, Aino; Grönlund-Brown, Inger; Ziedén, Bo; Minnhagen, Karin; Lindvall, Peter; Fant, Kristina; Kaczynski, Jacek; Wallmark, Anders; Wallén, Carl-Erik; Wallberg, Håkan; Grönquist, Lennart; Hansen, John Albert; Björkander, Inge; Timberg, Ingar; Rosenqvist, Ulf; Fries, Robert; Carlsson, Jan-Erik; Rautio, Aslak Tauno; Sjöberg, Lennart; Wirdby, Alexander; Höök, Peter; Larsson, Åsa; Bergström, Catharina Lysell; Jwayed, Addnan; Smolowicz, Adam; Lindman, Anne-Christine; Nilsson, Per; Tarrach, Gerrit; Carlsson, Ingolf; Wieloch, Mattias; Rindevall, Peter; Strömblad, Gunnar; Holmberg, Göran; Shahnazarian, Henrik; Melchior, Jan; Younan, Kamal; Hansson, Anders; Bjurklint, Dag; Borgencrantz, Bertil; Sjöström, Malin; Mullaart, Mikael; Munoz, Marjatta; Jakkola, Vallentina; Romot, Jaan; Dash, Rabinarayan; Magnusson, Jan-Olof; Ahmed, Saman; Jonsson, Christina; Pipkorn, Owe; Bray, Edward; Wolff, Aneas; Black, Iain; Head, Christopher; Allan, Anthony

    2011-01-01

    To assess the prevalence of persistent lipid abnormalities in statin-treated patients with diabetes with and without the metabolic syndrome. This was a cross-sectional study of 22,063 statin-treated outpatients consecutively recruited by clinicians in Canada and 11 European countries. Patient

  19. Communication of 29 April 1996 received from the Permanent Mission of the Russian Federation to the International Atomic Energy Agency regarding guidelines for the export of nuclear material, equipment and technology

    International Nuclear Information System (INIS)

    1996-01-01

    The document contains the text of a note verbale dated 29 April 1996 received by the Director General of IAEA from the Permanent Mission of the Russian Federation which provides information on the export policies and practices of the Government of the Russian Federation with respect to transfer of nuclear-related dual-use equipment, material and related technology

  20. Letter to the Editor: The Surge of Type 2 Diabetes Mellitus in China - an International Alert: Physical Exercise and Low-Caloric Diet May Reduce the Risks of Type 2 Diabetes Mellitus and Dementia.

    Science.gov (United States)

    Kao, Pai C; Han, Qiao Jun; Liu, Shuyi; Li, Xiu Jun; Inman, Kristin S; Chia, Nicholas

    2016-01-01

    The prevalence of diabetes in China has surged from 0.67% before 1980 to 11.6% currently. It is even higher than the prevalence in the United States. Certainly, China's economic open-ups, improving living standard, and modernization have propagated the surge. From a traditional public-health point of view, increased food intake and decreased exercise were the main contributors. A new knowledge of colon microbiota could be applied to provide a second harvest of food energy; for example, large molecules of carbohydrates, which are undigested by the stomach and small intestine, produce by-products that the body can absorb in the colon. Colon microbiota can ferment these carbohydrates to the short-chain fatty acid butyrate. This is an energy source that may even cause nonalcoholic fatty liver. How these colon microbiota contribute to the surge of diabetes and whether this new knowledge can be used to control diabetes and metabolic syndrome are questions for future scientific studies. Clinically, however, colon microbiota have had immediate applications; fecal microbiota have been transplanted from healthy persons to treat recurrent Clostridium difficile infection at Mayo Clinic. In addition, a stool biobank of healthy persons was established at Mayo Clinic for future clinical applications. © 2016 by the Association of Clinical Scientists, Inc.

  1. Federal Fleet Report

    Data.gov (United States)

    General Services Administration — Annual report of Federal agencies' motor vehicle fleet data collected in the Federal Automotive Statistical Tool (FAST), a web-based reporting tool cosponsored by...

  2. Framing Canadian federalism

    National Research Council Canada - National Science Library

    Saywell, John; Anastakis, Dimitry; Bryden, Penny E

    2009-01-01

    ... the pervasive effects that federalism has on Canadian politics, economics, culture, and history, and provide a detailed framework in which to understand contemporary federalism. Written in honour of John T. Saywell's half-century of accomplished and influential scholarly work and teaching, Framing Canadian Federalism is a timely and fitting t...

  3. Islet cell research brings hope for a diabetes cure: meeting report from the 6(th) annual islet society meeting in Stellenbosch, South Africa.

    Science.gov (United States)

    Tchokonte-Nana, V; Cockburn, I L; Manda, J K; Kotze, P C; Johnson, J D

    2014-01-01

    The International Diabetes Federation predicts that, over the next twenty years, the largest increase in the prevalence of diabetes will be in the Africa region. Recognizing an unmet need for more focus on Africa and engagement with African scholars, the Islet Society held its 6th annual meeting July 20-21, 2014 in Stellenbosch, South Africa. Here, we present a report that covers the presentations and discussion points from that meeting. Work was presented on a variety of topics and included presentations by a significant proportion of Africa diabetes researchers. Overall, it was an excellent conference, with many new international collaborations initiated. We hope that other groups will also respond to the need for more conferences in Africa and focused on Africa.

  4. Diabetes Insipidus

    Science.gov (United States)

    Diabetes insipidus (DI) causes frequent urination. You become extremely thirsty, so you drink. Then you urinate. This ... is almost all water. DI is different from diabetes mellitus (DM), which involves insulin problems and high ...

  5. Diabetes Complications

    Science.gov (United States)

    If you have diabetes, your blood glucose, or blood sugar, levels are too high. Over time, this can cause problems with other body ... as your kidneys, nerves, feet, and eyes. Having diabetes can also put you at a higher risk ...

  6. Diabetes Myths

    Science.gov (United States)

    ... Text Size: A A A Listen En Español Diabetes Myths On behalf of the millions of Americans ... or obese, you will eventually develop type 2 diabetes. Fact: Being overweight is a risk factor for ...

  7. Diabetic Neuropathy

    Science.gov (United States)

    ... of diabetic neuropathy may become severe enough to cause depression in some patients. x Prognosis The prognosis for ... of diabetic neuropathy may become severe enough to cause depression in some patients. View Full Prognosis Clinical Trials ...

  8. Diabetic Retinopathy

    Science.gov (United States)

    ... Prevalence Rates for Diabetic Retinopathy by Age, and Race/Ethnicity Hispanic Americans age 50 and older are ... Ethnicity 2010 Prevalence Rates of Diabetic Retinopathy by Race In 2010, Hispanic Americans age 50 and older ...

  9. Women and Diabetes

    Medline Plus

    Full Text Available ... Diabetes How to Report Problems with Glucose Meters Diabetes Treatments Some people with diabetes need to take diabetes ... talk with your health care provider about your diabetes treatment. Diabetes Medicines - easy-to-read booklet for women ...

  10. Sucrose octasulfate dressing versus control dressing in patients with neuroischaemic diabetic foot ulcers (Explorer): an international, multicentre, double-blind, randomised, controlled trial.

    Science.gov (United States)

    Edmonds, Michael; Lázaro-Martínez, José Luis; Alfayate-García, Jesus Manuel; Martini, Jacques; Petit, Jean-Michel; Rayman, Gerry; Lobmann, Ralf; Uccioli, Luigi; Sauvadet, Anne; Bohbot, Serge; Kerihuel, Jean-Charles; Piaggesi, Alberto

    2018-03-01

    Diabetic foot ulcers are serious and challenging wounds associated with high risk of infection and lower-limb amputation. Ulcers are deemed neuroischaemic if peripheral neuropathy and peripheral artery disease are both present. No satisfactory treatment for neuroischaemic ulcers currently exists, and no evidence supports one particular dressing. We aimed to assess the effect of a sucrose octasulfate dressing versus a control dressing on wound closure in patients with neuroischaemic diabetic foot ulcers. We did a randomised, double-blind clinical trial (Explorer) in 43 hospitals with specialised diabetic foot clinics in France, Spain, Italy, Germany, and the UK. Eligible participants were inpatients or outpatients aged 18 years or older with diabetes and a non-infected neuroischaemic diabetic foot ulcer greater than 1 cm 2 and of grade IC or IIC (as defined by the University of Texas Diabetic Wound Classification system). We excluded patients with a severe illness that might lead to them discontinuing the trial and those who had surgical revascularisation in the month before study entry. We randomly assigned participants (1:1) via a computer-generated randomisation procedure (concealed block size two); stratified by study centre and wound area (1-5 cm 2 and 5-30 cm 2 ), to treatment with either a sucrose octasulfate wound dressing or a control dressing (the same dressing without sucrose octasulfate) for 20 weeks. Both groups otherwise received the same standard of care for a 2-week screening period before randomisation and throughout the 20-week trial. Dressings were applied by nursing staff (or by instructed relatives for some outpatients). Frequencies of dressing changes were decided by the investigator on the basis of the clinical condition of the wound. Patients were assessed 2 weeks after randomisation, then monthly until week 20 or occurrence of wound closure. The primary outcome, assessed by intention-to-treat, was proportion of patients with wound closure at

  11. Roux-en-Y Gastric Bypass versus Intensive Medical Management for the Control of Type 2 Diabetes, Hypertension and Hyperlipidemia: An International, Multicenter, Randomized Trial

    Science.gov (United States)

    Ikramuddin, Sayeed; Korner, Judith; Lee, Wei-Jei; Connett, John E.; Inabnet, William B.; Billington, Charles B.; Thomas, Avis J.; Leslie, Daniel B.; Chong, Keong; Jeffery, Robert W.; Ahmed, Leaque; Vella, Adrian; Chuang, Lee-Ming; Bessler, Marc; Sarr, Michael G.; Swain, James M.; Laqua, Patricia; Jensen, Michael D.; Bantle, John P.

    2014-01-01

    Context Guideline directed care for diabetes calls for control of glycemia, blood pressure and cholesterol (composite goal). Most patients treated medically do not reach this goal. Objective Determine the efficacy and safety of Roux-en-Y gastric bypass (RYGB) added to lifestyle modification and intensive medical management (LS/IMM) to achieve control of all 3 endpoints. Design Two-arm unblinded randomized clinical trial with 120 participants. The primary endpoint of the composite outcome was assessed at 12 months. The study began in April 2008 and completed one year follow-up in all participants in December 2012. Setting Four academic teaching hospitals in the U.S. and Taiwan, involving five operating surgeons. Participants Inclusion criteria for the Diabetes Surgery Study (DSS) included HbA1c ≥ 8.0%, BMI 30.0-39.9 kg/m2, diagnosis and treatment of type 2 diabetes for at least six months, and stimulated C peptide > 1.0 ng/ml. Interventions All patients received lifestyle intervention modeled after the Look AHEAD study. Medications for hyperglycemia, hypertension, and dyslipidemia were prescribed according to protocol. RYGB techniques were standardized. Main Outcome Measure Attainment of a composite goal: HbA1c Nutritional deficiency of iron, vitamin B12 and albumin were observed more frequently with RYGB. Conclusions In mild to moderately obese patients with type 2 diabetes addition of RYGB to LS/IMM resulted in greater likelihood of achieving the composite treatment goal. RYGB participants required fewer medications but had more complications. PMID:23736733

  12. Self-monitoring of blood glucose (SMBG) and glycaemic control in Cameroon: Results of the International Diabetes Management Practices Study (IDMPS).

    Science.gov (United States)

    Claude Mbanya, Jean; Aschner, Pablo; Chan, Juliana C N; Jose Gagliardino, Juan; Saji, Jude

    2017-04-01

    This study examined the relationship between self-monitoring of blood glucose (SMBG) and glycaemic control among patients from Cameroon. A minority of patients with diabetes owned a blood glucose meter; of these patients, most performed SMBG inconsistently. The lack of SMBG may be a contributing factor to the poor glycaemic control in the country. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. Monogenic Diabetes

    Science.gov (United States)

    ... form of monogenic diabetes? • What type of monogenic diabetes does my child (or do I) have? • What are the treatment options? • What are the advantages and disadvantages of each treatment option? • Should I see a diabetes educator? • Should I see an endocrinologist? Resources • Find- ...

  14. Diagnosis of Diabetes and Prediabetes

    Science.gov (United States)

    ... Diabetes Medicines Pancreatic Islet Transplantation Diabetes Diet, Eating, & Physical Activity Carbohydrate Counting & Diabetes Preventing Diabetes Problems Diabetic Neuropathy Diabetes, Heart Disease, ...

  15. Assessment of Parametrial Response by Growth Pattern in Patients With International Federation of Gynecology and Obstetrics Stage IIB and IIIB Cervical Cancer: Analysis of Patients From a Prospective, Multicenter Trial (EMBRACE)

    Energy Technology Data Exchange (ETDEWEB)

    Yoshida, Kenji [Medical University of Vienna, Comprehensive Cancer Center, Vienna (Austria); Kobe University Graduate School of Medicine, Kobe (Japan); Jastaniyah, Noha [Medical University of Vienna, Comprehensive Cancer Center, Vienna (Austria); King Faisal Specialist Hospital and Research Center, Riyadh (Saudi Arabia); Sturdza, Alina, E-mail: alina.sturdza@akhwien.at [Medical University of Vienna, Comprehensive Cancer Center, Vienna (Austria); Lindegaard, Jacob [Aarhus University Hospital, Aarhus (Denmark); Segedin, Barbara [Institute of Oncology Ljubljana, Ljubljana (Slovenia); Mahantshetty, Umesh [Tata Memorial Hospital, Mumbai (India); Rai, Bhavana [Post Graduate Institute of Medical Education and Research, Chandigarh (India); Jürgenliemk-Schulz, Ina [University Medical Center, Utrecht (Netherlands); Haie-Meder, Christine [Institut Gustave Roussy, Paris (France); Sasaki, Ryohei [Kobe University Graduate School of Medicine, Kobe (Japan); Pötter, Richard [Medical University of Vienna, Comprehensive Cancer Center, Vienna (Austria)

    2015-11-15

    Purpose: To assess disease response along the parametrial space according to tumor morphology in patients with International Federation of Gynecology and Obstetrics (FIGO) stage IIB and IIIB cervical cancer at the time of image-guided adaptive brachytherapy. Methods and Materials: Patients with FIGO stage IIB and IIIB cervical cancer registered as of November 2013 in the EMBRACE study were evaluated. Tumors were stratified according to morphologic subtype on magnetic resonance imaging (expansive and infiltrative), and the characteristics of those subtypes were analyzed. Parametrial involvement at diagnosis and at brachytherapy was evaluated, and the response to chemo-radiotherapy was classified as good, moderate, or poor. The response grade was compared between the 2 groups and analyzed with regard to tumor volumes, and dosimetric parameters. Results: A total of 452 patients were evaluated, of whom 186 had expansive growth type and 266 had infiltrative morphology. Patients with infiltrative tumors had more extensive disease, as indicated by a higher rate of FIGO stage IIIB disease, as well as radiologic evidence of extension into the distal parametrial space and to the pelvic side wall on magnetic resonance imaging. Cervical necrosis was more common in the infiltrative group. Good response was more common in the expansive group (34% vs 24%; P=.02), and poor response was more common in the infiltrative group (11% and 19%; P=.02). Mean gross tumor volume at diagnosis was equal in both groups (51.7 cm{sup 3}). The high-risk clinical target volume was larger in infiltrative tumors (37.9 cm{sup 3} vs 33.3 cm{sup 3}, P=.005). The mean high-risk clinical target volume D{sub 90} was slightly higher in expansive tumors (92.7 Gy and 89.4 Gy, P<.001). Conclusion: Infiltrative tumors are more advanced at presentation and respond less favorably to chemo-radiotherapy when compared with expansive tumors that are more or less equivalent in size. The use of image

  16. Diabetes insipidus - nephrogenic

    Science.gov (United States)

    Nephrogenic diabetes insipidus; Acquired nephrogenic diabetes insipidus; Congenital diabetes insipidus; NDI ... of very dilute urine. NDI is rare. Congenital diabetes insipidus is present at birth. It is a ...

  17. European Nicotinamide Diabetes Intervention Trial (ENDIT)

    DEFF Research Database (Denmark)

    Gale, E A M; Bingley, P J; Emmett, C L

    2004-01-01

    to assess whether high dose nicotinamide prevents or delays clinical onset of diabetes in people with a first-degree family history of type 1 diabetes. METHOD: We did a randomised double-blind placebo-controlled trial of nicotinamide in 552 relatives with confirmed islet cell antibody (ICA) levels of 20...... Juvenile Diabetes Federation (JDF) units or more, and a non-diabetic oral glucose tolerance test. Participants were recruited from 18 European countries, Canada, and the USA, and were randomly allocated oral modified release nicotinamide (1.2 g/m2) or placebo for 5 years. Random allocation was done...

  18. Serum chromium concentrations in type 2 diabetic patients attending ...

    African Journals Online (AJOL)

    FPG). Lower serum chromium concentrations and poor chromium status are common in type 2 diabetics in Osogbo, Nigeria. Keywords: Diabetes, serum chromium, glucose tolerance, insulin. International Journal of Natural and Applied Sciences ...

  19. Gestational diabetes

    OpenAIRE

    Dragoš, Andreja

    2014-01-01

    Gestational diabetes is diabetes that occurs for the first time during pregnancy. In Slovenia, between 2.8 and 4.5 percent of pregnant women are affected by this disease. The number of women with gestational diabetes is increasing due to unhealthy lifestyle and most of all due to increasing occurrence of obesity. Gestational diabetes is a growing problem in Slovenia, as well as in the world. The purpose of the thesis is to establish the main risk factors for gestational diabetes and determ...

  20. The microcirculation in diabetes.

    Science.gov (United States)

    McMillan, D E

    1984-02-01

    Diabetes affects the microcirculation, the large arteries and occasionally the large and small veins, by inducing vessel wall sclerosis. The degree of stiffening produced is linked to its duration. The ability of the diabetic's circulation to distribute blood is affected, especially during increased blood flow. In most tissues this causes no serious burden, but three tissues are unusually susceptible to disturbance--the retina, renal cortex, and peripheral nerve. They develop serious problems in many longstanding diabetics. Damage to the kidney appears to be linked to its unique combination of high blood flow rate and precise control of intraglomerular filtration pressure. As renal arteriolar intima hyalinizes, the glomerular mesangium increases in volume. Diabetic renal changes appear to become irreversible when a critical stage, manifested be albuminuria and hypertension, is reached. The resulting renal failure is associated with clumpy deposits of type IV collagen in the cortex, suggesting that local microvascular autoregulation has been lost. The retinal circulation forms late in fetal life in a process in which local oxygen tension controls new vessel formation. In adult diabetics, local retinal oxygenation is disrupted by a condition called capillary closure, and intraretinal microaneurysms form. In advanced retinopathy, new microvessel systems grow into the vitreous through defects in the internal limiting membrane, producing hemorrhage and vitreous opacification. Macular degeneration is also seen in older diabetics, suggesting that the choroidal circulation may also be compromised. Evidence for a microcirculatory role in diabetic peripheral nerve damage is not as conclusive as for the kidney and retina. The longest peripheral nerves are typically the most affected. Recent studies suggest that nerve damage can be produced by a disturbance in local pressure-flow relationships combined with epineurial mechanical constraint. Hypotheses about the pathogenesis of

  1. Diabetic retinopathy

    DEFF Research Database (Denmark)

    Wong, Tien Y; Cheung, Chui Ming Gemmy; Larsen, Michael

    2016-01-01

    Diabetic retinopathy (DR) is a common complication of diabetes mellitus and is a major cause of vision loss in middle-aged and elderly people. One-third of people with diabetes have DR. Severe stages of DR include proliferative DR, caused by the abnormal growth of new retinal blood vessels......, and diabetic macular oedema, in which there is exudation and oedema in the central part of the retina. DR is strongly associated with a prolonged duration of diabetes, hyperglycaemia and hypertension. It is traditionally regarded as a microvascular disease, but retinal neurodegeneration is also involved...... (VEGF). Optimal control of blood glucose and blood pressure in individuals with diabetes remains the cornerstone for preventing the development and arresting the progression of DR. Anti-VEGF therapy is currently indicated for diabetic macular oedema associated with vision loss, whereas laser...

  2. Federal environmental inspections handbook

    International Nuclear Information System (INIS)

    1991-10-01

    This Federal Environmental Inspection Handbook has been prepared by the Department of Energy (DOE), Office of Environmental Guidance, RCRA/CERCLA Division (EH-231). It is designed to provide DOE personnel with an easily accessible compilation of the environmental inspection requirements under Federal environmental statutes which may impact DOE operations and activities. DOE personnel are reminded that this Handbook is intended to be used in concert with, and not as a substitute for, the Code of Federal Regulations (CFR). Federal Register (FR), and other applicable regulatory documents

  3. Changes in the Prevalence of Diabetes Mellitus in Bulgaria (2006–2012

    Directory of Open Access Journals (Sweden)

    Anna-Maria Borissova

    2015-01-01

    Full Text Available Aim The aim of this study was to compare two nationwide cross-sectional studies of diabetes prevalence in Bulgaria (2006 and 2012 and to assess its dynamics. Material and Methods The two studies included 2396 and 2033 subjects, respectively. The International Diabetes Federation (IDF diagnostic criteria were applied, and the data were weighed for type of settlement and age. Results Diabetes prevalence was found to be 7.9% in 2006 and 9.55% in 2012, P = 0.06, showing an increase of 20.9%. The absolute increase was 0.9% in the females and 2.3% in the males ( P < 0.09. The increase was the largest in those aged 50–59: [9.4%, 2006 vs. 15.7%, 2012, P < 0.01]. Diabetes prevalence increased in the 20–60-year olds by 6.8% and decreased in the elderly by 6.1%. Obesity increased from 26.7 to 32.7%, P < 0.02. Conclusions A significant increase in diabetes prevalence was found that necessitates healthcare measures and resources for community-based awareness and prevention programs.

  4. Metabolic syndrome and risk of incident diabetes: findings from the European Prospective Investigation into Cancer and Nutrition-Potsdam Study

    Directory of Open Access Journals (Sweden)

    Joost Hans-Georg

    2008-12-01

    Full Text Available Abstract Background Several aspects concerning the relationship between the metabolic syndrome and incident diabetes are incompletely understood including the magnitude of the risk estimate, potential gender differences in the associations between the metabolic syndrome and incident diabetes, the associations between the components of the metabolic syndrome and incident diabetes, and whether the metabolic syndrome provides additional prediction beyond its components. To shed light on these issues, we examined the prospective association between the metabolic syndrome defined by the National Cholesterol Education Program (NCEP and International Diabetes Federation (IDF and diabetes. Methods We used data for 2796 men and women aged 35–65 years from the European Prospective Investigation into Cancer and Nutrition-Potsdam Study followed for an average of 6.9 years. This analysis employed a case-cohort design that included 697 participants who developed diabetes and 2099 participants who did not. Incident diabetes was identified on the basis of self-reports and verified by contacting the patient's attending physician. Results The adjusted hazard ratio for the NCEP definition was 4.62 (95% confidence interval [CI]: 3.90–5.48 and that for the IDF definition was 4.59 (95% CI: 3.84–5.50. The adjusted hazard ratios for the NCEP but not IDF definition were higher for women than men. When participants who had no cardiometabolic abnormalities were used as the reference group for the NCEP definition, the adjusted hazard ratio for having 3 or more abnormalities increased to 22.50 (95% CI: 11.21–45.19. Of the five components, abdominal obesity and hyperglycemia were most strongly associated with incident diabetes. Conclusion In this study population, both definitions of the metabolic syndrome provided similar estimates of relative risk for incident diabetes. The increase in risk for participants with the metabolic syndrome according to the NCEP

  5. ETHNICITY AND TYPE 2 DIABETES IN ASIAN INDIAN MIGRANTS IN AUCKLAND, NEW ZEALAND

    Directory of Open Access Journals (Sweden)

    Jowitt Ljiljana

    2014-12-01

    Full Text Available The aim of this review was to present ethnic differences in body size and body composition in Asian Indian migrants in New Zealand, associated with metabolic syndrome and type 2 diabetes, through the comparison with other ethnic groups in New Zealand. International databases including PubMed and Google scholar were consulted, as well as the websites of the World Health Organization and International Diabetes Federation. About 74 studies out of 128 publications were selected to ensure relevance to the topic of the review. Seven research projects were presented for the body size and body composition of Asian Indian migrants in New Zealand. The prevalence of type 2 diabetes of 8.6% in Asian Indians in New Zealand is still higher than in their homeland, owing to their ethnicity, genetic predisposition, sedentary lifestyle and altered nutrition, and other psychosocial factors related to migration and living conditions like stress at work and depression. For the same body mass index, in comparison with people of other ethnic groups in New Zealand Asian Indians had more total body fat, higher percent body fat, more central fat, less lean mass and appendicular skeletal muscle mass. Central obesity was associated with insulin resistance and low grade systemic inflammation. Considering the evidence that type 2 diabetes develops ten years earlier in Asian Indians than in other populations, further studies are warranted to shed some light on the still incompletely understood metabolic syndrome and “thin-fat” Indian phenotype.

  6. Energy transition in federalism

    International Nuclear Information System (INIS)

    Mueller, Thorsten; Kahl, Hartmut

    2015-01-01

    The conference transcript assemble the presentations of the 10th Wuerzburg discussions for environmental energy law. The contributions discuss the political development objectives of the Federal Government and Federal States as well as the coordination tasks between the different political levels, inter alia, of constitutional and European law perspective. [de

  7. [Diabetic neuropathy].

    Science.gov (United States)

    Chudzik, Wiesław; Kaczorowska, Beata; Przybyła, Monika; Chudzik, Bartosz; Gałka, Małgorzata

    2007-01-01

    Diabetic neuropathy is most common chronic complication of diabetes mellitus. It is responsible for substantial morbidity, increased mortality and impaired quality of life. Patogenesis of diabetic neuropathy is complex. Chronic hyperglycemia is a major factor induces nerve fibers injury. High level of glucose stimulate the polyol pathway causing osmotic stress and enhance reactive oxygen species generation, as well as it play an important role in diabetic angiopathy development. Distal symmetric polineuropathy is most common type of diabetic neuropathy. Many patient may develop combinations of neuropathies concerning somatic and autonomic system. Early diagnosis and administered suitable treatment are necessary to reduce severe complication of diabetic neuropathy as well as strict glycemic control and risk factor increased.

  8. Women and Diabetes

    Medline Plus

    Full Text Available ... Emergency Preparedness International Programs News & Events Training & Continuing Education Inspections & Compliance Federal, State & Local Officials Consumers Health Professionals Science & Research Industry Scroll back to top Popular Content Home Latest Recalls Report an Adverse Event MedWatch Safety ...

  9. Increasing incidence of diabetes after gestational diabetes

    DEFF Research Database (Denmark)

    Lauenborg, Jeannet; Hansen, Torben; Jensen, Dorte Møller

    2004-01-01

    To study the incidence of diabetes among women with previous diet-treated gestational diabetes mellitus (GDM) in the light of the general increasing incidence of overweight and diabetes and to identify risk factors for the development of diabetes....

  10. Diabetic Foot

    OpenAIRE

    Halil Akbulut; Umit Aydogan; Y. Cetin Doganer

    2010-01-01

    Diabetes Mellitus is a multisystemic disease progressively seen more frequently in the general population. Diabetes foot, seen in patients suffering from diabetes mellitus, is a frequent result of improper foot care and requires long and serious treatment. The disease plays an important role in terms of public health and can be a cause for high morbidity and mortality rates. [TAF Prev Med Bull 2010; 9(4.000): 375-382

  11. Agreement of 13 December 1991 between the Republic of Argentina, the Federative Republic of Brazil, the Brazilian-Argentine Agency for Accounting and Control of Nuclear Materials and the International Atomic Energy Agency for the applications of safeguards

    International Nuclear Information System (INIS)

    1998-01-01

    The document reproduces the text of an Agreement by exchange of letters with the Federative Republic of Brazil in connection with the Treaty for the Prohibition of Nuclear Weapons in Latin America and the Caribbean. The agreement reflected in the Exchange of Letters was approved by the Board of Governors on 10 June 1997 and entered into force on that date

  12. District of Columbia Public Education: Agencies Have Enhanced Internal Controls over Federal Payments for School Improvement, but More Consistent Monitoring Needed. Report to Congressional Requesters. GAO-11-16

    Science.gov (United States)

    Ashby, Cornelia M.

    2010-01-01

    Between fiscal years 2004 and 2009, Congress appropriated nearly $190 million in federal payments for school improvement to the District of Columbia (D.C.). This includes $85 million to the state education office--currently the Office of the State Superintendent of Education (OSSE)--to expand public charter schools and $105 million to D.C. Public…

  13. Women and Diabetes

    Medline Plus

    Full Text Available ... How to Report Problems with Glucose Meters Diabetes Treatments Some people with diabetes need to take diabetes ... with your health care provider about your diabetes treatment. Diabetes Medicines - easy-to-read booklet for women ...

  14. Diabetes Movie (For Parents)

    Medline Plus

    Full Text Available ... Your Child About the News Brain and Nervous System Cancers When Your Child Needs a Kidney Transplant ... Diabetes: Lindsey's Story (Video) Diabetes Center Movie: Endocrine System Diabetes Center Diabetes: DJ's Story (Video) Diabetes: Marco's ...

  15. Living With Diabetes

    Science.gov (United States)

    ... Problems Diabetes & Sexual & Urologic Problems Clinical Trials Managing Diabetes You can manage your diabetes and live a ... you have diabetes. How can I manage my diabetes? With the help of your health care team, ...

  16. Diabetes Fact Sheet

    Science.gov (United States)

    ... this section Home A-Z Health Topics Diabetes Diabetes > A-Z Health Topics Diabetes (PDF, 438 KB) ... To receive Publications email updates Enter email Submit Diabetes Diabetes is a disease in which blood sugar ( ...

  17. Genetics of Diabetes

    Science.gov (United States)

    ... A A A Listen En Español Genetics of Diabetes You've probably wondered how you developed diabetes. ... to develop diabetes than others. What Leads to Diabetes? Type 1 and type 2 diabetes have different ...

  18. Diabetes eye exams

    Science.gov (United States)

    Diabetic retinopathy - eye exams; Diabetes - eye exams; Glaucoma - diabetic eye exam; Macular edema - diabetic eye exam ... if the doctor who takes care of your diabetes checks your eyes, you need an eye exam ...

  19. Types of Diabetes

    Science.gov (United States)

    ... Diabetes & Sexual & Urologic Problems Clinical Trials What is Diabetes? Diabetes is a disease that occurs when your ... is serious. What are the different types of diabetes? The most common types of diabetes are type ...

  20. Type 1 diabetes

    Science.gov (United States)

    Insulin-dependent diabetes; Juvenile onset diabetes; Diabetes - type 1; High blood sugar - type 1 diabetes ... Type 1 diabetes can occur at any age. It is most often diagnosed in children, adolescents, or young adults. Insulin is ...

  1. Women and Diabetes

    Medline Plus

    Full Text Available ... diabetes. Food Safety for People with Diabetes Your Glucose Meter - easy-to-read booklet for women Other ... Information on Diabetes How to Report Problems with Glucose Meters Diabetes Treatments Some people with diabetes need ...

  2. Diabetes and exercise

    Science.gov (United States)

    Exercise - diabetes; Exercise - type 1 diabetes; Exercise - type 2 diabetes ... a bracelet or necklace that says you have diabetes. Tell coaches and exercise partners that you have diabetes. Always have fast- ...

  3. Increasing incidence of diabetes after gestational diabetes

    DEFF Research Database (Denmark)

    Lauenborg, Jeannet; Hansen, Torben; Jensen, Dorte Møller

    2004-01-01

    To study the incidence of diabetes among women with previous diet-treated gestational diabetes mellitus (GDM) in the light of the general increasing incidence of overweight and diabetes and to identify risk factors for the development of diabetes.......To study the incidence of diabetes among women with previous diet-treated gestational diabetes mellitus (GDM) in the light of the general increasing incidence of overweight and diabetes and to identify risk factors for the development of diabetes....

  4. Prevalence of Hypertension, Obesity, Diabetes, and Metabolic Syndrome in Nepal

    Directory of Open Access Journals (Sweden)

    Sanjib Kumar Sharma

    2011-01-01

    Full Text Available Background. This study was carried out to establish the prevalence of cardiovascular risks such as hypertension, obesity, and diabetes in Eastern Nepal. This study also establishes the prevalence of metabolic syndrome (MS and its relationships to these cardiovascular risk factors and lifestyle. Methods. 14,425 subjects aged 20–100 (mean 41.4 ± 15.1 were screened with a physical examination and blood tests. Both the International Diabetic Federation (IDF and National Cholesterol Education Programme’s (NCEP definitions for MS were used and compared. Results. 34% of the participants had hypertension, and 6.3% were diabetic. 28% were overweight, and 32% were obese. 22.5% of the participants had metabolic syndrome based on IDF criteria and 20.7% according to the NCEP definition. Prevalence was higher in the less educated, people working at home, and females. There was no significant correlation between the participants’ lifestyle factors and the prevalence of MS. Conclusion. The high incidence of dyslipidemia and abdominal obesity could be the major contributors to MS in Nepal. Education also appears to be related to the prevalence of MS. This study confirms the need to initiate appropriate treatment options for a condition which is highly prevalent in Eastern Nepal.

  5. Proceedings of the National Institute of Diabetes and Digestive and Kidney Diseases International Symposium on Epidemiologic Issues in Urinary Incontinence in Women

    DEFF Research Database (Denmark)

    Brown, Jeanette S.; Nyberg, Leroy M.; Kusek, John W.

    2003-01-01

    The Epidemiologic Issues in Urinary Incontinence: Current Databases and Future Collaborations Symposium included an international group of 29 investigators from 10 countries. The purpose of the symposium was to discuss the current understanding and knowledge gaps of prevalence, incidence, associa......The Epidemiologic Issues in Urinary Incontinence: Current Databases and Future Collaborations Symposium included an international group of 29 investigators from 10 countries. The purpose of the symposium was to discuss the current understanding and knowledge gaps of prevalence, incidence......, associated risk factors, and treatment outcomes for incontinence in women. During the symposium, investigators identified existing large databases and ongoing studies that provide substantive information on specific incontinence research questions. The investigators were able to form an international...

  6. 26 CFR 31.6011(a)-3 - Returns under Federal Unemployment Tax Act.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 15 2010-04-01 2010-04-01 false Returns under Federal Unemployment Tax Act. 31... Provisions of Subtitle F, Internal Revenue Code of 1954) § 31.6011(a)-3 Returns under Federal Unemployment Tax Act. (a) Requirement. Every person shall make a return of tax under the Federal Unemployment Tax...

  7. Diabetes and Pregnancy: Gestational Diabetes

    Centers for Disease Control (CDC) Podcasts

    2007-11-14

    Gestational diabetes happens in a woman who develops diabetes during pregnancy. This podcast discusses its potential effects and action steps to avoid complications.  Created: 11/14/2007 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP), Division of Diabetes Translation (DDT) and National Center on Birth Defects and Developmental Disabilities (NCBDDD), Prevention Research Branch.   Date Released: 11/27/2007.

  8. FEDERAL BALANCING IN NIGERIA: A PARADIGM FOR ...

    African Journals Online (AJOL)

    user

    In Nigeria presently, the crisis of federalism has gone beyond the case of bickering among ethnic groups .... Internal affairs, Finance and Health are considered very important. So these juicy portfolios need to be fairly ..... President Shehu Shagari in 1980 but it submitted its report in 1981. It was headed by Dr. Pius Okigbo, ...

  9. Diabetic Coma

    Science.gov (United States)

    ... can lead to: Permanent brain damage Death Prevention Good day-to-day control of your diabetes can help you prevent a diabetic coma. Keep these tips in mind: Follow your meal plan. Consistent snacks and meals can help you control your blood ...

  10. Diabetes mellitus

    NARCIS (Netherlands)

    Ahdi, M.; Gerdes, V. E.; Hoekstra, J. B.; Meesters, E. W.

    2012-01-01

    Currently there are over 740,000 patients with diabetes mellitus in the Netherlands, and this number will increase further in the coming years. Approximately 90% of patients has type 2 diabetes, a metabolic disorder that is often associated with obesity, hypertension and increased cholesterol

  11. Agreement of 13 December 1991 between the Republic of Argentina, the Federative Republic of Brazil, the Brazilian-Argentine Agency for Accounting and Control of Nuclear Materials and the International Atomic Energy Agency for the application of safeguards

    International Nuclear Information System (INIS)

    2000-01-01

    The document reproduces the text of the Exchange of Letters concerning an agreement with the Federative Republic of Brazil in connection with the Treaty on the Non-Proliferation of Nuclear Weapons and the Treaty for the Prohibition of Nuclear Weapons in Latin America and the Caribbean. The agreement reflected in the Exchange of Letters was approved by the Board of Governors on 20 September 1999, and entered into force on that date

  12. Risk of Metabolic Syndrome and Diabetes Mellitus Among Young Twins and Singletons in Guinea-Bissau

    DEFF Research Database (Denmark)

    Bjerregaard-Andersen, Morten; Hansen, Lone; da Silva, Leontina I

    2013-01-01

    OBJECTIVETwins in Africa may be at increased risk of metabolic disorders due to strained conditions in utero, including high exposure to infections. We studied metabolic syndrome (MS) and diabetes mellitus (DM) among young twins and singletons in Guinea-Bissau.RESEARCH DESIGN AND METHODSThe study...... was cross-sectional and occurred from October 2009 until August 2011 at the Bandim Health Project, a demographic surveillance site in the capital Bissau. Twins and singleton controls between 5 and 32 years were visited at home. Fasting blood samples for metabolic measurements were collected. Zygosity...... was established genetically for a subset. DM was defined as HbA1c ≥6.5% (48 mmol/mol) and MS by the International Diabetes Federation criteria.RESULTSHbA1c was available for 574 twins and 463 singletons. Mean age was 15.3 years versus 15.8 years, respectively. Eighteen percent of twins were monozygotic...

  13. ACA Federal Upper Limits

    Data.gov (United States)

    U.S. Department of Health & Human Services — Affordable Care Act Federal Upper Limits (FUL) based on the weighted average of the most recently reported monthly average manufacturer price (AMP) for...

  14. New Mexico Federal Lands

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This map layer consists of federally owned or administered lands of the United States, Puerto Rico, and the U.S. Virgin Islands. Only areas of 640 acres or more are...

  15. Federal Ballpark Estimator

    Data.gov (United States)

    Office of Personnel Management — The Federal Ballpark E$timate(R) was developed by the Employee Benefit Research Institute(R) and its American Savings Education Council(R) (ASEC(R)) program. It is...

  16. Federal Medication Terminologies

    Science.gov (United States)

    Federal Medication (FedMed) collaboration of 8 partner agencies agreed on a set of standard, comprehensive, freely and easily accessible FMT terminologies to improve the exchange and public availability of medication information.

  17. Federal Assembly, Prague

    Czech Academy of Sciences Publication Activity Database

    Hnídková, Vendula

    -, č. 37 (2011), s. 70 ISSN 1573-3815 Institutional research plan: CEZ:AV0Z80330511 Keywords : Czech architecture of the 20th century * Karel Prager * federal assembly Subject RIV: AL - Art, Architecture , Cultural Heritage

  18. Integrated vs. Federated Search

    DEFF Research Database (Denmark)

    Løvschall, Kasper

    2009-01-01

    Oplæg om forskelle og ligheder mellem integrated og federated search i bibliotekskontekst. Holdt ved temadag om "Integrated Search - samsøgning i alle kilder" på Danmarks Biblioteksskole den 22. januar 2009.......Oplæg om forskelle og ligheder mellem integrated og federated search i bibliotekskontekst. Holdt ved temadag om "Integrated Search - samsøgning i alle kilder" på Danmarks Biblioteksskole den 22. januar 2009....

  19. From design to implementation - The Joint Asia Diabetes Evaluation (JADE program: A descriptive report of an electronic web-based diabetes management program

    Directory of Open Access Journals (Sweden)

    Lyubomirsky Greg

    2010-05-01

    Full Text Available Abstract Background The Joint Asia Diabetes Evaluation (JADE Program is a web-based program incorporating a comprehensive risk engine, care protocols, and clinical decision support to improve ambulatory diabetes care. Methods The JADE Program uses information technology to facilitate healthcare professionals to create a diabetes registry and to deliver an evidence-based care and education protocol tailored to patients' risk profiles. With written informed consent from participating patients and care providers, all data are anonymized and stored in a databank to establish an Asian Diabetes Database for research and publication purpose. Results The JADE electronic portal (e-portal: http://www.jade-adf.org is implemented as a Java application using the Apache web server, the mySQL database and the Cocoon framework. The JADE e-portal comprises a risk engine which predicts 5-year probability of major clinical events based on parameters collected during an annual comprehensive assessment. Based on this risk stratification, the JADE e-portal recommends a care protocol tailored to these risk levels with decision support triggered by various risk factors. Apart from establishing a registry for quality assurance and data tracking, the JADE e-portal also displays trends of risk factor control at each visit to promote doctor-patient dialogues and to empower both parties to make informed decisions. Conclusions The JADE Program is a prototype using information technology to facilitate implementation of a comprehensive care model, as recommended by the International Diabetes Federation. It also enables health care teams to record, manage, track and analyze the clinical course and outcomes of people with diabetes.

  20. Diabetic embryopathy.

    Science.gov (United States)

    Eriksson, Ulf J; Wentzel, Parri

    2012-01-01

    Diabetic embryopathy reflects a scientific enigma--how does a seemingly rich intrauterine environment manage to disturb the development of the embryo? Which compounds in that environment may be teratogenic--and how shall we find them? How can we investigate a putative dose-response nature of the teratogen, i.e., how can we monitor the effects of varied severity of the diabetic state (which can be varied in a number of metabolic ways) on the embryonic development? Here, the whole embryo culture (WEC) technique provides an excellent tool for such studies. WEC is thus currently used to investigate the effect of graded levels of diabetes (e.g., hyperglycemia, hyperketonemia, increased branched chain amino acid (BCAA) levels), and putative antiteratogenic agents (antioxidants, folic acid, arachidonic acid, inositol), as well as the effect of different embryonic genotypes on diabetes-induced (mal)development. WEC is the only method, which is able to couple specific embryonic maldevelopment to precise changes in substrate levels or the (epi)genotype of the embryo. Using this method, we have been able to demonstrate that a diabetic environment--culture of embryos in serum from diabetic animals or in serum with increased levels of glucose, β-hydroxybutyrate or α-ketoisocaproic acid (KIC)--causes increased embryonic maldevelopment, and that this dysmorphogenesis is blocked by the addition of ROS scavenging agents to the culture medium. Genetically, others and we have demonstrated that Pax-3 downregulation predisposes for diabetes-induced dysmorphogenesis.

  1. Diabetic nephropathy

    Directory of Open Access Journals (Sweden)

    Zelmanovitz Themis

    2009-09-01

    Full Text Available Abstract Diabetic nephropathy is the leading cause of chronic renal disease and a major cause of cardiovascular mortality. Diabetic nephropathy has been categorized into stages: microalbuminuria and macroalbuminuria. The cut-off values of micro- and macroalbuminuria are arbitrary and their values have been questioned. Subjects in the upper-normal range of albuminuria seem to be at high risk of progression to micro- or macroalbuminuria and they also had a higher blood pressure than normoalbuminuric subjects in the lower normoalbuminuria range. Diabetic nephropathy screening is made by measuring albumin in spot urine. If abnormal, it should be confirmed in two out three samples collected in a three to six-months interval. Additionally, it is recommended that glomerular filtration rate be routinely estimated for appropriate screening of nephropathy, because some patients present a decreased glomerular filtration rate when urine albumin values are in the normal range. The two main risk factors for diabetic nephropathy are hyperglycemia and arterial hypertension, but the genetic susceptibility in both type 1 and type 2 diabetes is of great importance. Other risk factors are smoking, dyslipidemia, proteinuria, glomerular hyperfiltration and dietary factors. Nephropathy is pathologically characterized in individuals with type 1 diabetes by thickening of glomerular and tubular basal membranes, with progressive mesangial expansion (diffuse or nodular leading to progressive reduction of glomerular filtration surface. Concurrent interstitial morphological alterations and hyalinization of afferent and efferent glomerular arterioles also occur. Podocytes abnormalities also appear to be involved in the glomerulosclerosis process. In patients with type 2 diabetes, renal lesions are heterogeneous and more complex than in individuals with type 1 diabetes. Treatment of diabetic nephropathy is based on a multiple risk factor approach, and the goal is retarding the

  2. Federal Measures Against the Abuse of Wild Animals

    Science.gov (United States)

    Reed, Nathaniel P.

    1974-01-01

    Describes the appalling conditions associated with many zoos and with the trafficking of exotic pets, and discusses recent federal and international measures designed to reduce the abuse of wild animals. (JR)

  3. Indications and outcome of admission of diabetic patients into the ...

    African Journals Online (AJOL)

    2012-01-01

    Patient/materials and methods: A retrospective description of both types 1 and 2 diabetics at the medical wards of Federal Medical Centre, Makurdi from January 1, 2012 to December 31, 2013. Age, gender, diagnosis and outcome were extracted fromadmissions/discharge logs. Diagnosis of diabetes was based on fasting ...

  4. Diabetes mellitus

    OpenAIRE

    Skiadopoulos, Dionysios

    2013-01-01

    This theses on Diabetes Mellitus aims at giving an insight at various aspects of this chronic disease and the risk factors that lead to it; the varius ways it develops in the human body; the old and new approaches to treatment, both from a pharmacological and a non- pharmacologiacal point of view; ways to prevent and to manage the diabetes complications; how to improve the live of the diabetic patients who are faced with not only physical but also psychological problems; statistical data from...

  5. Federal Offshore Statistics, 1993. Leasing, exploration, production, and revenue as of December 31, 1993

    Energy Technology Data Exchange (ETDEWEB)

    Francois, D.K.

    1994-12-31

    This document contains statistical data on the following: federal offshore lands; offshore leasing activity and status; offshore development activity; offshore production of crude oil and natural gas; federal offshore oil and natural gas sales volume and royalties; revenue from federal offshore leases; disbursement of federal offshore revenue; reserves and resource estimates of offshore oil and natural gas; oil pollution in US and international waters; and international activities and marine minerals. A glossary is included.

  6. Use of the smartphone application "Pregnant with Diabetes"

    DEFF Research Database (Denmark)

    Nørgaard, Sidse Kjærhus; Nichum, Vibeke Ladefoged; Barfred, Charlotte

    2017-01-01

    INTRODUCTION: The aim of this article was to evaluate the awareness and use of the smartphone application (app) "Pregnant with Diabetes" locally, nationally and internationally. METHODS: In 2013, a patient initiated collaboration with the staff at Centre for Pregnant Women with Diabetes, Rigs...... antenatal visit in early pregnancy at our centre. National and international data on numbers of downloads were obtained from Google Play, from the App Store and from Google Analytics. RESULTS: Among 139 pregnant women with diabetes (96 with Type 1 diabetes and 43 with Type 2 diabetes), 99% had a smartphone...

  7. 76 FR 20359 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings

    Science.gov (United States)

    2011-04-12

    ... Diabetes and Digestive and Kidney Diseases Special Emphasis Panel; PA10-067: Stem Cells and Diabetic Skin... Major Ongoing Clinical Research Studies in CKD (R01). Date: May 17, 2011. Time: 2 p.m. to 3:30 p.m... . (Catalogue of Federal Domestic Assistance Program Nos. 93.847, Diabetes, Endocrinology and Metabolic Research...

  8. 78 FR 3903 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Meetings

    Science.gov (United States)

    2013-01-17

    ... Diseases Advisory Council, Diabetes, Endocrine and Metabolic Diseases Subcommittee. Date: February 13, 2013... Diabetes and Digestive and Kidney Diseases; Notice of Meetings Pursuant to section 10(d) of the Federal... Diabetes and Digestive and Kidney Diseases Advisory Council. The meetings will be open to the public as...

  9. Patients' Evaluation of the Quality of Diabetes Care (PEQD)

    DEFF Research Database (Denmark)

    Pouwer, F; Snoek, Frank J

    2002-01-01

    variables, HbA1c, number of diabetes complications, satisfaction with diabetes care, diabetes related distress, and fear of hypoglycaemia were assessed by self-report. In addition, satisfaction with diabetes care and evaluations about quality of the care were measured at 16 month follow up. Statistical...... analysis comprised principal component analyses, Cronbach's alpha, t tests, Pearson's correlation, and linear regression analyses. RESULTS: Results in the literature were used to develop the 14 items of the Patients' Evaluation of the Quality of Diabetes Care (PEQD) scale, assessing the most important...... aspects of the quality of diabetes care as delivered by the specialist in internal medicine (internist) and the diabetes nurse specialist (DNS). Two principal components analyses (internist/DNS) both yielded one 14 item factor with a high internal consistency. Satisfaction with diabetes care, fewer...

  10. Relationship of soft drink consumption to global overweight, obesity, and diabetes: a cross-national analysis of 75 countries.

    Science.gov (United States)

    Basu, Sanjay; McKee, Martin; Galea, Gauden; Stuckler, David

    2013-11-01

    We estimated the relationship between soft drink consumption and obesity and diabetes worldwide. We used multivariate linear regression to estimate the association between soft drink consumption and overweight, obesity, and diabetes prevalence in 75 countries, controlling for other foods (cereals, meats, fruits and vegetables, oils, and total calories), income, urbanization, and aging. Data were obtained from the Euromonitor Global Market Information Database, the World Health Organization, and the International Diabetes Federation. Bottled water consumption, which increased with per-capita income in parallel to soft drink consumption, served as a natural control group. Soft drink consumption increased globally from 9.5 gallons per person per year in 1997 to 11.4 gallons in 2010. A 1% rise in soft drink consumption was associated with an additional 4.8 overweight adults per 100 (adjusted B; 95% confidence interval [CI] = 3.1, 6.5), 2.3 obese adults per 100 (95% CI = 1.1, 3.5), and 0.3 adults with diabetes per 100 (95% CI = 0.1, 0.8). These findings remained robust in low- and middle-income countries. Soft drink consumption is significantly linked to overweight, obesity, and diabetes worldwide, including in low- and middle-income countries.

  11. Optimal cutoff points for the detection of undiagnosed type 2 diabetes, hypertension and metabolic syndrome in Mexican adults.

    Science.gov (United States)

    Rojas-Martínez, Rosalba; Aguilar-Salinas, Carlos A; Jiménez-Corona, Aída

    2012-01-01

    To compare the waist circumference cutoff points established by the American Heart Association and the National Heart, Lung and Blood Institute (AHA/NHLBI) with those of the International Diabetes Federation (IDF) for the screening of diabetes, hypertension, and metabolic syndrome in Mexican adults. This study comprised a subsample of the ENSANUT 2006. Subjects without diabetes and hypertension and non-pregnant women were included. Sensitivity, specificity, and predictive values were compared using AUC and the positive likelihood ratio test [LR(+)]. In subjects aged ≥40 years, sensitivity for detection of diabetes and hypertension was higher for the IDF thresholds (85.34 and 86.87%, respectively) compared with those of the AHA/NHLBI (59.49 and 52.41%, respectively). LR(+) were higher for IDF thresholds compared with AHA/NHLBI. Similar results in subjects aged ≥65 years were observed. The measurement of abdominal obesity defined by the IDF was a better screening tool for diabetes and hypertension, considering that initially a high sensitivity and low cost tool at population level is required.

  12. Metabolic syndrome in type 2 diabetes: comparative prevalence according to two sets of diagnostic criteria in sub-Saharan Africans

    Directory of Open Access Journals (Sweden)

    Kengne Andre P

    2012-05-01

    Full Text Available Abstract Background Available definition criteria for metabolic syndrome (MS have similarities and inconsistencies. The aim of this study was to determine the prevalence of MS in a group of Cameroonians with type 2 diabetes, according to the International Diabetes Federation (IDF and the National Cholesterol Education Programme Adult Treatment Panel III (NCEP-ATP III criteria, and to assess the concordance between both criteria, and the implications of combining them. Methods We collected clinical and biochemical data for 308 patients with type 2 diabetes (men 157 at the National Obesity Center of the Yaounde Central Hospital, Cameroon. Concordance was assessed with the use of the Kappa statistic. Results Mean age (standard deviation was 55.8 (10.5 years and the median duration of diagnosed diabetes (25th–75th percentiles was 3 years (0.5–5.0, similarly among men and women. The prevalence of MS was 71.7% according to the IDF criteria and 60.4% according to NCEP-ATP III criteria. The prevalence was significantly higher in women than in men independently of the criteria used (both p  Conclusions The IDF and NCEP-ATP III criteria do not always diagnose the same group of diabetic individuals with MS and combining them merely increases the yield beyond that provided by the IDF definition alone. This study highlights the importance of having a single unifying definition for MS in our setting.

  13. Federalism and Health Care

    Directory of Open Access Journals (Sweden)

    G. Alan Tarr

    2011-10-01

    Full Text Available President Barack Obama proposed a major overhaul of the American healthsystem, and in 2010 the U.S. Congress enacted his proposal, the PatientProtection and Affordable Care Act. Opponents of the Act challenged itsconstitutionality in federal court, claiming that it exceeds the powers grantedto the federal government under the Commerce Clause and the NecessaryProper Clause of the federal Constitution. Some courts have upheldthe law, but others have agreed with the critics, in particular ruling thatthe provision requiring citizens to buy health insurance is unconstitutional.Eventually the U.S. Supreme Court will rule on the issue. This article tracesthe controversy, surveys the interpretation of pertinent constitutional provisionsin past cases, analyzes the constitutional arguments presented byproponents and opponents of the Act, and concludes that the Act is constitutional.

  14. [Diabetes insipidus].

    Science.gov (United States)

    Krysiak, Robert; Handzlik-Orlik, Gabriela; Okopień, Bogusław

    2014-01-01

    Diabetes insipidus is an uncommon disorder of water-electrolyte balance characterized by the excretion of abnormally large volumes of diluted urine (polyuria) and increased fluid intake (polydipsia). The disease may result from the insufficient production of vasopressin, its increased degradation, an impaired response of kidneys to vasopressin, or may be secondary to excessive water intake. Patients with severe and uncompensated symptoms may develop marked dehydration, neurologic symptoms and encephalopathy, and therefore diabetes insipidus can be a life-threatening condition if not properly diagnosed and managed. Patients with diabetes insipidus require treatment with desmopressin or drugs increasing sensitivity of the distal nephron to vasopressin, but this treatment may be confusing because of the disorder's variable pathophysiology and side-effects of pharmacotherapy. This review summarizes the current knowledge on different aspects of the pathophysiology, classification, clinical presentation, diagnosis, and management of diabetes insipidus. The reader is also provided with some practical recommendations on dealing with patients suffering from this disease.

  15. Diabetic Retinopathy.

    African Journals Online (AJOL)

    AmL

    Haddad et al(13) had defined many associated factors with DR, mainly age of patients, duration of diabetes, presence of heart disease, hypertension, high blood glucose level and dyslipidemia. However, after adjustment for covariates, duration.

  16. Diabetes Superfoods

    Science.gov (United States)

    ... key healthy fats along with helping to manage hunger. In addition, they offer magnesium and fiber. Some ... Offices Volunteer Opportunities Signature Events Camps Diabetes EXPOs Awareness Programs Wellness Lives Here Become a Member American ...

  17. Immunizations - diabetes

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/patientinstructions/000331.htm Immunizations - diabetes To use the sharing features on this page, please enable JavaScript. Immunizations (vaccines or vaccinations) help protect you from some ...

  18. Gestational diabetes

    Science.gov (United States)

    ... right for you. Low-impact exercises, such as swimming, brisk walking, or using an elliptical machine are ... chap 45. Moyer VA; US Preventive Services Task Force. Screening for gestational diabetes mellitus: US Preventive Services ...

  19. Diabetic Ketoacidosis

    Science.gov (United States)

    ... ketones build up in the blood and eventually "spill over" into the urine. Diabetic ketoacidosis is usually ... your heart, muscles and nerves. Swelling in the brain (cerebral edema). Adjusting your blood sugar level too ...

  20. Diabetes Insipidus

    Science.gov (United States)

    ... Diabetes Inspidus Related Topics Section Navigation Kidney Disease Acquired Cystic Kidney Disease Amyloidosis & Kidney Disease Chronic Kidney ... nausea Severe dehydration can lead to seizures, permanent brain damage, and even death. Seek Immediate Care Usually, people ...