WorldWideScience

Sample records for international activities includes

  1. Managing nuclear knowledge: IAEA activities and international coordination. Including resource material full text CD-ROM

    International Nuclear Information System (INIS)

    2005-06-01

    The present CD-ROM summarizes some activities carried out by the Departments of Nuclear Energy and Nuclear Safety and Security in the area of nuclear knowledge management in the period 2003-2005. It comprises, as open resource, most of the relevant documents in full text, including policy level documents, reports, presentation material by Member States and meeting summaries. The collection starts with a reprint of the report to the IAEA General Conference 2004 on Nuclear Knowledge [GOV/2004/56-GC(48)/12] summarizing the developments in nuclear knowledge management since the 47th session of the General Conference in 2003 and covers Managing Nuclear Knowledge including safety issues and Information and Strengthening Education and Training for Capacity Building. It contains an excerpt on Nuclear Knowledge from the General Conference Resolution [GC(48)/RES/13] on Strengthening the Agency's Activities Related to Nuclear Science, Technology and Applications. On the CD-ROM itself, all documents can easily be accessed by clicking on their titles on the subject pages (also printed at the end of this Working Material). Part 1 of the CD-ROM covers the activities in the period 2003-2005 and part 2 presents a resource material full text CD-ROM on Managing Nuclear Knowledge issued in October 2003

  2. PREFACE: 9th International Fröhlich's Symposium: Electrodynamic Activity of Living Cells (Including Microtubule Coherent Modes and Cancer Cell Physics)

    Science.gov (United States)

    Cifra, Michal; Pokorný, Jirí; Kucera, Ondrej

    2011-12-01

    This volume contains papers presented at the International Fröhlich's Symposium entitled 'Electrodynamic Activity of Living Cells' (1-3 July 2011, Prague, Czech Republic). The Symposium was the 9th meeting devoted to physical processes in living matter organized in Prague since 1987. The hypothesis of oscillation systems in living cells featured by non-linear interaction between elastic and electrical polarization fields, non-linear interactions between the system and the heat bath leading to energy downconversion along the frequency scale, energy condensation in the lowest frequency mode and creation of a coherent state was formulated by H Fröhlich, founder of the theory of dielectric materials. He assumed that biological activity is based not only on biochemical but also on biophysical mechanisms and that their disturbances form basic links along the cancer transformation pathway. Fröhlich outlined general ideas of non-linear physical processes in biological systems. The downconversion and the elastic-polarization interactions should be connected in a unified theory and the solution based on comprehensive non-linear characteristics. Biochemical and genetic research of biological systems are highly developed and have disclosed a variety of cellular and subcellular structures, chemical reactions, molecular information transfer, and genetic code sequences - including their pathological development. Nevertheless, the cancer problem is still a big challenge. Warburg's discovery of suppressed oxidative metabolism in mitochondria in cancer cells suggested the essential role of physical mechanisms (but his discovery has remained without impact on cancer research and on the study of physical properties of biological systems for a long time). Mitochondria, the power plants of the cell, have several areas of activity-oxidative energy production is connected with the formation of a strong static electric field around them, water ordering, and liberation of non

  3. International regulatory activities

    International Nuclear Information System (INIS)

    Anon.

    2009-01-01

    In this last part is reviewed international regulatory activities and bilateral agreements including two parts: concerning European atomic energy community with European commission proposal for a council directive setting up a community framework for nuclear safety, update of the nuclear illustrative programme in the context of the second strategic energy review, european commission recommendation on criteria for the export of radioactive waste and spent fuel to third countries and a communication on nuclear non-proliferation and the second part in relation with international atomic energy agency with a joint convention on the safety of spent fuel management and on safety of radioactive waste management (third review meeting). (N.C.)

  4. Including all voices in international data-sharing governance.

    Science.gov (United States)

    Kaye, Jane; Terry, Sharon F; Juengst, Eric; Coy, Sarah; Harris, Jennifer R; Chalmers, Don; Dove, Edward S; Budin-Ljøsne, Isabelle; Adebamowo, Clement; Ogbe, Emilomo; Bezuidenhout, Louise; Morrison, Michael; Minion, Joel T; Murtagh, Madeleine J; Minari, Jusaku; Teare, Harriet; Isasi, Rosario; Kato, Kazuto; Rial-Sebbag, Emmanuelle; Marshall, Patricia; Koenig, Barbara; Cambon-Thomsen, Anne

    2018-03-07

    Governments, funding bodies, institutions, and publishers have developed a number of strategies to encourage researchers to facilitate access to datasets. The rationale behind this approach is that this will bring a number of benefits and enable advances in healthcare and medicine by allowing the maximum returns from the investment in research, as well as reducing waste and promoting transparency. As this approach gains momentum, these data-sharing practices have implications for many kinds of research as they become standard practice across the world. The governance frameworks that have been developed to support biomedical research are not well equipped to deal with the complexities of international data sharing. This system is nationally based and is dependent upon expert committees for oversight and compliance, which has often led to piece-meal decision-making. This system tends to perpetuate inequalities by obscuring the contributions and the important role of different data providers along the data stream, whether they be low- or middle-income country researchers, patients, research participants, groups, or communities. As research and data-sharing activities are largely publicly funded, there is a strong moral argument for including the people who provide the data in decision-making and to develop governance systems for their continued participation. We recommend that governance of science becomes more transparent, representative, and responsive to the voices of many constituencies by conducting public consultations about data-sharing addressing issues of access and use; including all data providers in decision-making about the use and sharing of data along the whole of the data stream; and using digital technologies to encourage accessibility, transparency, and accountability. We anticipate that this approach could enhance the legitimacy of the research process, generate insights that may otherwise be overlooked or ignored, and help to bring valuable

  5. Mathematics of flexible risers including pressure and internal flow affects

    Energy Technology Data Exchange (ETDEWEB)

    Seyed, F.B. (John Brown Engineers and Constructors Ltd., London (GB)); Patel, M.H. (University Coll., London (GB). Dept. of Mechanical Engineering)

    1992-01-01

    Derivations are presented for calculation of pressure and internal flow induced forces on flexible risers and other curved pipes using a mathematically rigorous approach. Approximate and exact methods are presented for calculation of pressure forces on straight and curved pipes in two dimensions. The mathematical identity of these equations with those for effective tension is illustrated. The force arising from the flow of an internal fluid of constant density is then calculated and combined with those for pressure forces in derivation of the catenary equations including pressure and internal flow terms. It is shown that internal flow contributes a new term to the expression for effective tension. These governing equations are then reduced for the specific cases of simple catenary, steep-S, lazy-S, steep-wave and lazy-wave risers. In each case, the solution method has been presented and the governing equilibrium and geometric compatability conditions cited. (author).

  6. International regulatory activities

    International Nuclear Information System (INIS)

    Anon.

    2002-01-01

    Different international regulatory activities are presented: recommendation on the protection of the public against exposure to radon in drinking water supplies, amendment to the legislation implementing the regulation on imports of agricultural products originating in third countries following the Chernobyl accident, resolution on the commission green paper towards a European strategy for the security of energy supply, declaration of mandatory nature of the international code for the safe carriage of packaged irradiated nuclear fuel, plutonium and high level radioactive wastes on board ships, adoption of action plan against nuclear terrorism. (N.C.)

  7. International regulatory activities

    International Nuclear Information System (INIS)

    Anon.

    2010-01-01

    Concerning International regulatory activities, we find for the european atomic energy community an entry into force of the lisbon treaty (2009), it amends the treaty on European union and replaces the treaty establishing the European Community by the new treaty on the functioning of the European Union; more, an amendment to council regulation on the conditions governing imports of agricultural products originating in third countries following the accident at the Chernobyl nuclear power station (2009). About International atomic energy agency is reported an open-ended meeting of technical and legal experts for sharing of information on states implementation of the code of conduct on the safety and security of radioactive sources and its supplementary guidance on the import and export of radioactive sources (2010). (N.C.)

  8. International regulatory activities

    International Nuclear Information System (INIS)

    Anon.

    2003-01-01

    Among international regulatory activities we find resolutions adopted by the IAEA general conference (2003), through European Union we find proposals for directives on nuclear safety and radioactive waste management, new regulation on the application of EURATOM safeguards, control of high activity sealed radioactive sources, recommendation on the protection and information of the public with regard to the continued contamination of certain wild food products following the Chernobyl accident, proposals for decisions authorizing the Member states to sign and ratify the Protocol to amend the Paris convention, p)proposals for a directive on environment liability with regard to the prevention and remedying of environmental damage, proposal of a regulation on the law applicable to non-contractual obligation. (N.C.)

  9. A qualitative description of falls in a neuro-rehabilitation unit: the use of a standardised fall report including the International Classification of Functioning (ICF) to describe activities and environmental factors.

    Science.gov (United States)

    Saverino, Alessia; Moriarty, Amy; Rantell, Khadija; Waller, Denise; Ayres, Rachael; Playford, Diane

    2015-01-01

    Falls are a recognised problem for people with long-term neurological conditions but less is known about fall risk in young adults. This study describes fallers' and falls' characteristics in adults less than 60 years old, in a neuro-rehabilitation unit. This single-centre, longitudinal, observational study included 114 consecutive admissions to a UK neuro-rehabilitation unit over 20 months. The demographic and clinical characteristics of eligible patients included age, sex, diagnosis, hospital length of stay and the Functional Independence Measure (FIM). Falls were recorded prospectively in a fall report, using the activities and environmental domains of the International Classification of Functioning (ICF). A total of 34 (30%) patients reported a fall, with 50% experiencing more than one fall. The majority of falls (60%) occurred during the first 2 weeks, during day-time (90%) and during mobile activities (70%). Overall, falls rate (95% confidence interval) was 1.33 (1.04 to 1.67) per 100 d of patient hospital stay. Factors associated with increased falls included becoming a walker during admission or being cognitively impaired. There were no serious fall-related injuries. The first 2 weeks of admission is a high risk time for fallers, in particular those who become walkers or are cognitively impaired. Prevention policies should be put in place based on fall characteristics. Implications for Rehabilitation The ICF is a valuable instrument for describing subject and environmental factors during a fall-event. Falls are frequent events but do not usually cause serious injuries during inpatient rehabilitation. There is an increased fall risk for subjects with cognitive impairments or those relearning how to walk.

  10. NEW TRENDS IN INTERNATIONAL ENTREPRENEURSHIP: INSIGHTS FROM CONTEMPORARY TURKISH FIRMS INCLUDING BORN GLOBALS

    Directory of Open Access Journals (Sweden)

    Sinan NARDALI

    2015-07-01

    Full Text Available Academic literature has examined phenomenon of entrepreneurship more thantwo decades and thisphenomenon associated with entrepreneurial activity. OECDdefines the entrepreneurial activity as the enterprising human action in pursuit ofthe generation of value, through the creation or expansion of economic activity,by identifying and exploiting new products, process or markets. Present studyanalyses international entrepreneurship in the lights of contemporary Turkishfirms including born globals.We used case studies and literature review to betterunderstand the early internalization phenomenon and provide useful informationabout international success of Turkish firms. Six of the considered firms are webbased technology companies and most of them have born global firms’ features.The findings indicatedthatmajority of thefirms are technology companies andtheyhad a strong international outlook and international entrepreneurialorientation and they possess a strong entrepreneurial mindset.

  11. Review of Hanford international activities

    International Nuclear Information System (INIS)

    Panther, D.G.

    1993-01-01

    Hanford initiated a review of international activities to collect, review, and summarize information on international environmental restoration and waste management initiatives considered for use at Hanford. This effort focused on Hanford activities and accomplishments, especially international technical exchanges and/or the implementation of foreign-developed technologies

  12. International guidance activities

    International Nuclear Information System (INIS)

    Richardson, Allan C.B.

    1989-01-01

    International principles for setting Protective Action Guides (PAGs) are contained in two key documents that contain identical statements. One is Publication Number 40 of the ICRP, which was issued in 1985. The title is 'Protection of the Public in the Event of Major Radiation Accidents, Principles for Planning'. The other is the IAEA's Safety Series Publication Number 72, also issued in 1985, written by many of the same authors and titled, 'Principles for Establishing Intervention Levels'. The principles that were set forth in these documents were identical, were incomplete, and they are, unfortunately, the only principles that are now in effect, while proposed revisions go through one draft after another. There are several such draft revisions that are of significance. The most important is that of the ICRP. The basic guidance that applies to most planned exposure to radiation is ICRP Publication 26. That document has been under revision by the Commission for a number of years, and the new version will, for the first time, include recommendations for emergency response. They are now getting close to closure, and I think it should be a very much improved and useful document. But it isn't finished yet. Such guidance doesn't get developed in a vacuum, and there have been a couple of parallel efforts which have provided significant input to the ICRP, which is essentially a behind-closed-doors effort. These other efforts are more open. One of these is being carried out within the IAEA, which has convened annual meetings of national experts for a number of years in Vienna, to generate a replacement for Safety Series No. 72, mentioned earlier. There is a meeting scheduled this December to complete this effort; and, hopefully, we will reach closure at that meeting on at least the basic principles. The Nuclear Energy Agency (NEA) has also been at work. It has convened a group of experts from member nations that have been developing recommendations. There is an overlap

  13. Learning Activities for International Business.

    Science.gov (United States)

    Haynes, Thomas

    1998-01-01

    The National Standards for Business Education include nine areas relating to international business: awareness, communication, environmental factors, ethics, finance, management, marketing, import/export, and organizational structure of international business. (SK)

  14. International Union of Radioecologists' activities

    International Nuclear Information System (INIS)

    Auerbach, S.I.

    1983-01-01

    The International Union of Radioecologists (I.U.R.) has maintained a vigorous program of activities in accordance with the goals of its charter. To meet these goals, the I.U.R. has sponsored a number of workshops, meetings, and other related activities aimed at improving our ability to understand and predict the consequences of release of radionuclides to the environment. These include: intercomparison and harmonization of methodologies and a continuous feedback between scientists engaged in mathematical modeling and those carrying out field studies. Specialized workshops dealing with problems in understanding transfer coefficients in the terrestrial environment are being held. In the marine environment, long-distance transport in sediments plays an important role for the spread of radioisotopes released from reprocessing plants (e.g., in the Eastern Atlantic, the Northland Baltic Sea). Representatives of the countries concerned (including from Northern Countries) will define conditions of information exchange, sampling (time, character of sediments), and modelisation

  15. Active internal corrector coils

    International Nuclear Information System (INIS)

    Thompson, P.A.; Cottingham, J.; Dahl, P.

    1986-01-01

    Trim or corrector coils to correct main magnet field errors and provide higher multipole fields for beam optics purposes are a standard feature of superconducting magnet accelerator systems. This paper describes some of the design and construction features of powered internal trim coils and a sampling of the test results obtained

  16. International activities of the GRS

    International Nuclear Information System (INIS)

    Antoni, R.; Hachenberg, G.; Schally, P.

    1990-01-01

    The individual activities fall into three main subject areas, each with differing objectives and functions: Cooperation in multilateral and bilateral bodies and organizations, cooperation in international research projects, performance of safety analyses. In addition to describing the international activities of GRS, the paper also shows how complexly interwoven the safety of nuclear facilities is at the international level, and how varied initiatives are required in order to ensure effective cooperation in the various fields. (orig.) [de

  17. The International Active Learning Space

    DEFF Research Database (Denmark)

    Manners, Ian James

    2015-01-01

    -Danish students receive the basic international and intercultural skills and knowledge they need in current society. The English-language masters’ seminars I teach at the Department of Political Science are international in terms of students and teacher, but they are also Active Learning seminars......-Danish students (and sometimes teachers) rarely speak to each other or learn each other’s names. In the international AL spaces I create, students must work together on joint tasks which require interaction to address tasks and integration in order to benefit from the multinational activity groups. Planning AL...... that complete the seminar soon become vocal advocates of international AL. Ultimately, enriching student learning through immersing Danish and international students in an international AL space is, for me, the best way of ensuring an internationalised learning outcome, rather than just international mobility....

  18. International regulatory activities

    International Nuclear Information System (INIS)

    Anon.

    2004-01-01

    The 48. session of the IAEA general conference was held in Vienna from 20 to 24 september 2004 with the participation of delegates from 125 members states and representatives of various international organisations. A number of resolutions were adopted by the conference in the following fields: nuclear safety, radiation, transport and waste safety. The general conference also adopted a resolution on measures to protect against nuclear terrorism. The Director General decided in 2003 to appoint a group of experts to explore and advise on issues related to nuclear liability. This group called the International Expert Group on Nuclear Liability (I.N.L.E.X.) consists of 20 experts members from nuclear power and non nuclear power countries and from shipping and non shipping states. It serves three major functions: to create a forum of expertise to explore and advise on issues related to nuclear liability; to enhance global adherence by nuclear and non nuclear states to an effective nuclear liability regime, inter alia, on the basis of the convention on supplementary compensation for nuclear damage and the annex thereto, the Vienna convention on civil liability for nuclear damage, the Paris convention on third party liability in the field of nuclear energy, the joint protocol relating to the application of the vienna convention and the paris convention and the amendments thereto; and to assist in the development and strengthening of the national nuclear liability legal frameworks in IAEA members states to protect the public and the environment and to enhance nuclear safety. The second part of international regulatory concerns a directive on public access to environmental information made by the European Parliament. (N.C.)

  19. International regulatory activities

    International Nuclear Information System (INIS)

    Anon.

    1999-01-01

    The 43 rd Session of the IAEA General Conference was held in Vienna from 27 September to 1 October 1999 with delegations from 11 member states and representatives of various international organisations in attendance. Resolutions were adopted inter alia in the following areas: nuclear radiation and waste safety; strengthening IAEA technical co-operation; strengthening the IAEA's safeguards system; safeguards in the democratic people's republic of Korea; non proliferation safeguards in the middle east; illicit trafficking in nuclear materials and nuclear inspections in Iraq. The second part deals with the regulation laying down detailed rules for the application of the 1990 regulation on imports of agricultural products originating in third countries following the Chernobyl accident and recommendation on a classification system for solid radioactive waste. (A.L.B.)

  20. Rosatom international activities in 2011

    International Nuclear Information System (INIS)

    Lysenko, M.N.

    2011-01-01

    The Rosatom Corporation made some major strides in reinforcing the global nuclear safety arrangements, expanding its interactions with the IAEA and other notable international organizations. The article presents the momentous events in international activities of the Russian nuclear corporation, describes interaction with strategic partners and cooperation with IAEA, EURASEC and CIS-countries [ru

  1. In Vitro Activity of the New Fluoroketolide Solithromycin (CEM-101) against a Large Collection of Clinical Neisseria gonorrhoeae Isolates and International Reference Strains, Including Those with High-Level Antimicrobial Resistance: Potential Treatment Option for Gonorrhea?

    Science.gov (United States)

    Golparian, Daniel; Fernandes, Prabhavathi; Ohnishi, Makoto; Jensen, Jörgen S.

    2012-01-01

    Gonorrhea may become untreatable, and new treatment options are essential. We investigated the in vitro activity of the first fluoroketolide, solithromycin. Clinical Neisseria gonorrhoeae isolates and reference strains (n = 246), including the two extensively drug-resistant strains H041 and F89 and additional isolates with clinical cephalosporin resistance and multidrug resistance, were examined. The activity of solithromycin was mainly superior to that of other antimicrobials (n = 10) currently or previously recommended for gonorrhea treatment. Solithromycin might be an effective treatment option for gonorrhea. PMID:22354296

  2. 76 FR 45878 - Alticor, Inc., Including Access Business Group International LLC and Amway Corporation, Buena...

    Science.gov (United States)

    2011-08-01

    ...,420B] Alticor, Inc., Including Access Business Group International LLC and Amway Corporation, Buena Park, CA; Alticor, Inc., Including Access Business Group International LLC and Amway Corporation...., Including Access Business Group International LLC and Amway Corporation, Including On-Site Leased Workers...

  3. 75 FR 26794 - Alticor, Inc., Including Access Business Group International LLC and Amway Corporation, Buena...

    Science.gov (United States)

    2010-05-12

    ..., Inc., Including Access Business Group International LLC and Amway Corporation, Buena Park, CA; Alticor, Inc., Including Access Business Group International LLC, and Amway Corporation, Ada, MI; Amended... of Alticor, Inc., including Access Business Group International LLC and Amway Corporation, Buena Park...

  4. Developing Internal Controls through Activities

    Science.gov (United States)

    Barnes, F. Herbert

    2009-01-01

    Life events can include the Tuesday afternoon cooking class with the group worker or the Saturday afternoon football game, but in the sense that Fritz Redl thought of them, these activities are only threads in a fabric of living that includes all the elements of daily life: playing, working, school-based learning, learning through activities,…

  5. 75 FR 32221 - Alticor, Inc., Including Access Business Group International, LLC, and Amway Corporation...

    Science.gov (United States)

    2010-06-07

    ... Access Business Group International, LLC, and Amway Corporation, Including On-Site Leased Workers from... Business Group International, LLC and Amway Corporation. The notice was published in the Federal Register... issued as follows: All workers of Alticor, Inc., including Access Business Group International, LLC and...

  6. IPSN international activities in 1999

    International Nuclear Information System (INIS)

    Anon.

    2000-01-01

    This article is a reprint of a chapter taken from the 1999 activity report of the French Institute of Nuclear Protection and Safety (IPSN) and devoted to the international activities of the IPSN, in particular the cooperation of IPSN with its German homologue GRS (Gesellschaft fuer Anlagen und Reaktorsicherheit): assistance to Eastern Europe countries (development of regulation and constitution of safety files in Ukraine, transfer of computer codes and training, safety evaluation of the Mochvce nuclear power plant in Slovakia, reduction of the risks generated by the Tchernobyl shelter, assistance for the decommissioning of the Tchernobyl power plant, analysis of improvements proposed for the Medzamor unit 2 of Armenia, evaluation of fire hazard risks, assistance to Lithuania for the licensing of the Ignalina 1 unit); cooperation with China; international cooperation about the methods and tools for crisis management; international collaboration about IPSN's serious accident codes; extension of cooperation with Japan in radiation protection and radio-ecology; nuclear safety exercises in Russia and Armenia; development of Russia's national control of nuclear materials; collaboration with the medical radiological research center of Obninsk (Russia); radiation protection assistance in Turkey after a source accident; neutron measurements at the Vandellos 2 power plant (Spain); European intercomparison of neutron dosimetry; international intercomparison of uranium dosimetry in urines; participation to European research programs; construction of a database about the Tchernobyl accident consequences; organization of the Eurosafe European forum on the safety of nuclear facilities; development and validation of the Astec computer code for the simulation of nuclear accidents; evaluation report concerning the French-German EPR reactor project. (J.S.)

  7. International energy-promotion-activities

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-01

    Comprehensive promotion of energy and environmental measures are demanded in order to realize improvement in energy demand/supply structures in developing countries where increase in energy demand is anticipated. To achieve this goal, technical transfer related to energy saving technologies and clean coal as well as international energy promotion activities are implemented in China and Indonesia since fiscal 1993. In the field of energy saving, model operations are performed to improve efficiency in such energy consuming fields as steel making, power generation, and oil refining, in addition to cooperation in structuring databases and establishing master plans. In the clean coal field, model operations are conducted to reduce environmental load in coal utilizing areas, in addition to cooperation in establishing master plans for coal utilization. This paper describes feasibility studies on environmentally harmonious coal utilization systems in developing countries, assistance to introduction thereof, and joint verification operations. To rationalize international energy usage, basic surveys on energy utilization efficiency improvement and model operations are carried out mainly in the Asia-Pacific countries.

  8. Analysis of DOE international environmental management activities

    Energy Technology Data Exchange (ETDEWEB)

    Ragaini, R.C.

    1995-09-01

    The Department of Energy`s (DOE) Strategic Plan (April 1994) states that DOE`s long-term vision includes world leadership in environmental restoration and waste management activities. The activities of the DOE Office of Environmental Management (EM) can play a key role in DOE`s goals of maintaining U.S. global competitiveness and ensuring the continuation of a world class science and technology community. DOE`s interest in attaining these goals stems partly from its participation in organizations like the Trade Policy Coordinating Committee (TPCC), with its National Environmental Export Promotion Strategy, which seeks to strengthen U.S. competitiveness and the building of public-private partnerships as part of U.S. industrial policy. The International Interactions Field Office task will build a communication network which will facilitate the efficient and effective communication between DOE Headquarters, Field Offices, and contractors. Under this network, Headquarters will provide the Field Offices with information on the Administration`s policies and activities (such as the DOE Strategic Plan), interagency activities, as well as relevant information from other field offices. Lawrence Livermore National Laboratory (LLNL) will, in turn, provide Headquarters with information on various international activities which, when appropriate, will be included in reports to groups like the TPCC and the EM Focus Areas. This task provides for the collection, review, and analysis of information on the more significant international environmental restoration and waste management initiatives and activities which have been used or are being considered at LLNL. Information gathering will focus on efforts and accomplishments in meeting the challenges of providing timely and cost effective cleanup of its environmentally damaged sites and facilities, especially through international technical exchanges and/or the implementation of foreign-development technologies.

  9. [Effectiveness of mental health training including active listening for managers].

    Science.gov (United States)

    Ikegami, Kazunori; Tagawa, Yoshimasa; Mafune, Kosuke; Hiro, Hisanori; Nagata, Shoji

    2008-07-01

    significant increases post-training in "Job demands", "Worksite support by supervisor" and "Worksite support by co-worker", subscales of the BJSQ 12 items version. Particularly, the "Worksite support by supervisor" subscale increased significantly in 8 of the 47 sections in a comparison among sections. In this present study, we investigated the effectiveness of mental health training including Active Listening for managers, and suggest that to train Active Listening and use it at the worksite possibly strengthens "Worksite support by supervisor".

  10. Children and adolescents' internal models of food-sharing behavior include complex evaluations of contextual factors.

    Science.gov (United States)

    Markovits, Henry; Benenson, Joyce F; Kramer, Donald L

    2003-01-01

    This study examined internal representations of food sharing in 589 children and adolescents (8-19 years of age). Questionnaires, depicting a variety of contexts in which one person was asked to share a resource with another, were used to examine participants' expectations of food-sharing behavior. Factors that were varied included the value of the resource, the relation between the two depicted actors, the quality of this relation, and gender. Results indicate that internal models of food-sharing behavior showed systematic patterns of variation, demonstrating that individuals have complex contextually based internal models at all ages, including the youngest. Examination of developmental changes in use of individual patterns is consistent with the idea that internal models reflect age-specific patterns of interactions while undergoing a process of progressive consolidation.

  11. Report made on behalf of the commission of foreign affairs about the project of law, adopted by the senate, authorizing the approval of the agreement between the French government and the preliminary commission of the organization of the nuclear test ban treaty, about the conduct of the activities relative to the international control facilities, including the post-certification activities

    International Nuclear Information System (INIS)

    Cazenave, R.

    2003-12-01

    France and the preliminary commission of the comprehensive nuclear test ban treaty organization (CTBTO) concluded on July 13, 2001, an agreement about the conduct of the activities relative to the international surveillance facilities. This agreement aims at organizing the modalities of implementation of the surveillance activities carried out by the technical secretariat of the preliminary committee of CTBTO in the French territory. This document is the report of the French national assembly about the project of law for the approval of this agreement. It presents the difficult implementation of an international test ban system, the French commitment in the comprehensive nuclear test ban treaty (CTBT), and the main dispositions of the agreement of July 13, 2001. (J.S.)

  12. International Spinal Cord Injury Core Data Set (version 2.0)-including standardization of reporting

    NARCIS (Netherlands)

    Biering-Sorensen, F.; DeVivo, M. J.; Charlifue, S.; Chen, Y.; New, P. W.; Noonan, V.; Post, M. W. M.; Vogel, L.

    Study design: The study design includes expert opinion, feedback, revisions and final consensus. Objectives: The objective of the study was to present the new knowledge obtained since the International Spinal Cord Injury (SCI) Core Data Set (Version 1.0) published in 2006, and describe the

  13. 75 FR 77664 - Honeywell International, Inc., Automation and Control Solutions Division, Including On-Site...

    Science.gov (United States)

    2010-12-13

    ..., Inc., Automation and Control Solutions Division, Including On-Site Leased Workers From Manpower... Solutions Division. The Department has determined that these workers were sufficiently under the control of Honeywell International, Inc., Automation and Control Solutions Division to be considered leased workers...

  14. International Spinal Cord Injury Core Data Set (version 2.0)-including standardization of reporting

    NARCIS (Netherlands)

    Biering-Sørensen, F; DeVivo, M J; Charlifue, Susan; Chen, Y; New, P.W.; Noonan, V.; Post, M W M; Vogel, L.

    STUDY DESIGN: The study design includes expert opinion, feedback, revisions and final consensus. OBJECTIVES: The objective of the study was to present the new knowledge obtained since the International Spinal Cord Injury (SCI) Core Data Set (Version 1.0) published in 2006, and describe the

  15. Wideband CMOS low noise amplifier including an active balun

    NARCIS (Netherlands)

    Blaakmeer, S.C.; Klumperink, Eric A.M.; Leenaerts, D.M.W.; Nauta, Bram

    2007-01-01

    An inductorless LNA with active balun is proposed for multi-standard radio applications between 100MHz and 6GHz [1]. It exploits a combination of a common-gate (CG) stage and an common-source (CS) stage with replica biasing to maximize balanced operation, while simultaneously canceling the noise and

  16. EM international activities: May 1998 highlights

    International Nuclear Information System (INIS)

    1998-05-01

    This publication is produced twice a year by the International Technology Systems Application staff. This issue is divided into the following sections: (1) Global Issues Facing Environmental Management; (2) Activities in Western Europe; (3) Activities in Central and Eastern Europe; (4) Activities in Russia; (5) Activities in Asia and the Pacific Rim; (6) Activities in South America; (7) Activities in North America; (8) Country studies; and (9) International Organizations. Some topics discussed are nuclear materials management, radioactive waste and hazardous waste management, and remedial action programs

  17. NREL: International Activities - Country Programs

    Science.gov (United States)

    regional programs of the Africa Low Emissions Development Strategies (LEDS) Partnership, including information relevant to renewable energy development, such as transportation networks, transmission corridors China. India NREL teams with partners in India on renewable energy grid integration studies and regional

  18. China and IEC international standardization activities

    Institute of Scientific and Technical Information of China (English)

    Su Zhongmin; Guo Chenguang

    2006-01-01

    @@ International Electrotechnical Commission (IEC), one of the currently worlswide largest and most authoritative international standardization organizations,is specialized in developing and promulgating international standards for the electric and electronic fields, which are widespread adopted through out the world and play an important role in the international trade of electric and electronic products. Moreover, according to the 2005 statistics by the World Bank, the population of countries participating in the IEC activities accounts for 92% of the world total and their trade volume accounts for 95% of the global total.

  19. International collaboration including patients is essential to develop new therapies for patients with myositis.

    Science.gov (United States)

    Lundberg, Ingrid E; Vencovsky, Jiri

    2017-05-01

    To discuss the needs for international collaborations between investigators in different disciplines working with myositis and with patients with myositis. Recent advances in detection of several myositis-specific autoantibodies that are associated with distinct clinical phenotypes, will enable studies in new well defined clinically homogenous subgroups of myositis This is likely to lead to development of new information on molecular pathogenesis that might be different in different myositis subgroups. Subgrouping patients according to autoantibody profile may also be important to assess outcome, to identify prognostic biomarkers and in clinical trials. As these are rare disorders international collaboration is essential to enrol large enough cohorts of the subgroups. To facilitate such collaboration we have developed a web-based international myositis register, www.euromyositis.eu, which includes validated outcome measures and patient reported outcome measures. This register is to support research but also to support decision-making in the clinic. We welcome investigators to join the Euromyositis register. Myositis is a heterogeneous disorder with varying treatment response and outcome. There is a high unmet need for new therapies which can only be achieved by increased knowledge on molecular disease mechanisms. Subgrouping patients according to autoantibody profile may be a new way forward to get a better understanding on disease mechanisms and to develop novel therapies.

  20. Ademe - international activities report 2007

    International Nuclear Information System (INIS)

    2007-01-01

    The French Environment and Energy Management Agency (ADEME) is a public agency under the joint supervision of the French Ministries for Ecology, Energy, Sustainable Development and Spatial Planning, and for Higher Education and Research. It participates in the implementation of public policies in the fields of the environment, energy and sustainable development. The agency makes its expertise and consultancy skills available to business, local communities, public authorities and the general public and helps them to finance projects in five areas (waste management, soil preservation, energy efficiency and renewable energies, air quality and noise abatement) and to make progress with their sustainable development procedures. 2007 was an exceptional year for ADEME. The 'Grenelle de l'Environnement' was the Agency's opportunity to apply its expertise and promote its proposals. The fight to stop climate change is now one of society's top priorities. The Agency played an unprecedented role in advising the Government and Grenelle stakeholders on energy efficiency, energy management and renewable energy as well as air quality and efforts to stem noise pollution. ADEME's expertise gave renewed momentum to discussions on the topic of waste. ADEME also took an active role in discussions on sustainable production and consumption. The societal changes deemed necessary by participants in the 'Grenelle de l'Environnement' had been foreseen by ADEME. 2007 was also the first year of implementation for the new Charter agreement on objectives with the state. Priority was given to efforts to increase expertise, develop cross-functional approaches and demonstrate the effectiveness of the ADEME model, which permanently links research, field action, observation and evaluation. In 2008, ADEME will take on two challenges: translate the commitments of the 'Grenelle de l'Environnement' into concrete results and contribute to the French presidency of the European Union. Beyond its support for

  1. 78 FR 12357 - Brockway Mould, Inc., a Division of Ross International Ltd. Including Robert Lerch From BJR...

    Science.gov (United States)

    2013-02-22

    ... Division of Ross International Ltd. Including Robert Lerch From BJR Trucking, Brockport, PA; Amended..., applicable to workers and former workers of Brockway Mould, Inc., a division of Ross International Ltd... Brockway Mould, Inc., a division of Ross International Ltd., including Robert Lerch from BJR Trucking...

  2. Defining Adapted Physical Activity: International Perspectives

    Science.gov (United States)

    Hutzler, Yeshayahu; Sherrill, Claudine

    2007-01-01

    The purpose of this study was to describe international perspectives concerning terms, definitions, and meanings of adapted physical activity (APA) as (a) activities or service delivery, (b) a profession, and (c) an academic field of study. Gergen's social constructionism, our theory, guided analysis of multiple sources of data via qualitative…

  3. International program activities in magnetic fusion energy

    International Nuclear Information System (INIS)

    1986-03-01

    The following areas of our international activities in magnetic fusion are briefly described: (1) policy; (2) background; (3) strategy; (4) strategic considerations and concerns; (5) domestic program inplications, and (6) implementation. The current US activities are reviewed. Some of our present program needs are outlined

  4. International Charter "Space and Major Disasters": Typical Examples of Disaster Management Including Asian Tsunami

    Science.gov (United States)

    Cubero-Castan, Eliane; Bequignon, Jerome; Mahmood, Ahmed; Lauritson, Levin; Soma, P.; Platzeck, Gabriel; Chu, Ishida

    2005-03-01

    The International Charter 'Space and Major Disaster', now entering its 5th year of operation, has been activated nearly 80 times to provide space-based data and information in response to natural disasters. The disasters ranged from volcanic eruption in Columbia, floods in Europe, Argentina, Sudan to earthquakes in Iran, from landslides in Philippines to the tragic tsunami in Asia, all resulting in major loss of life and property. The Charter provided imagery and the related information were found to be useful in disaster relief and assessment. Since July 1st 2003, a framework cooperation agreement has been allowing United Nations organizations involved in disaster response to request activation of the Charter.The purpose of the Charter is to provide assistance in situations of emergencies caused by natural and technological disasters by pooling together the space and associated ground resources of the Charter participants, which are currently the European (ESA), French (CNES), Canadian (CSA), Indian (ISRO), American (NOAA), Argentinean (CONAE) and Japanese (JAXA) space organizations.This paper will point out some of the best cases of Charter activation for different disasters leading to change detection imagery and damage assessment products which could be used for disaster reduction in close co-ordination with the end users after the crisis period.

  5. ADEME - International activities report 2006

    International Nuclear Information System (INIS)

    2006-01-01

    policies and thanks to a very wide spectrum of actions it has been able to contribute to all of the previously mentioned developments: prolongation of national awareness campaigns, assistance in helping structure waste collection processes, notably WEEE (Waste Electric and Electronic Equipment), expert assistance for establishing energy saving certificates, initiatives in the banking sector to develop new instruments stimulating improved energy control... 2006 was also a year for ADEME to develop a new Charter Agreement on Objectives (COB) based on frequent and fruitful exchanges with its governing bodies. This contract which was signed on 21 December 2006 underlines the Agency's capacity to adapt as well as the evolution of its functions and will enable it, within a fast changing context, to better approach the deployment of its initiatives for the 2007-2010 period. The generalisation of public policies for environmental protection and energy management add support to the role of ADEME while in parallel requiring it to adapt its operational procedures by means of strengthening its capacities of providing expertise. This contract enables better organisation of the Agency's actions in its fields of action (waste and soils, air, noise, energy saving and renewable energies) through these being organised into 4 types of activities: - Developing knowledge through research and observation; - Heightening public awareness, convincing and mobilizing by means of communication and training; - Advising, directly or via relays, by developing adapted methods and tools; - Support to achieve projects by means of direct expert input or investment aid or by initiating new financing tools. In the coming years, ADEME will continue its evolution to adapt to society's requirements and will intensify its initiatives notably regarding to: - Stimulating research and innovation through 10 headline research programmes, from fundamental research to industrial development; - Observation of flows and

  6. The need to include Health Impact Assessment at the International Monetary Fund.

    Science.gov (United States)

    Cave, Ben; Birley, Martin

    2010-01-01

    The lending and technical support provided by the International Monetary Fund affect the determinants of health and healthy equity. Most health determinants lie outside the control of the health sector, and thus non-health-sector policies have profound positive and negative effects on population health. Health Impact Assessment (HIA) is an instrument for identifying the effect of policies, plans, programs, and projects on population health and health equity. It is a feasible, cost-effective, and transparent process that has been adopted by several financial institutions, including members of the World Bank Group. Adopting HIA would assist the IMF in ensuring that the potential health consequences of its policies are identified and addressed.

  7. Go local: morality and international activism

    Directory of Open Access Journals (Sweden)

    Aleksandar Jokic

    2013-03-01

    Full Text Available A step towards constructing an ethics of international activism is proposed by formulating a series of constraints on what would constitute morally permissible agency in the context that involves delivering services abroad, directly or indirectly. Perhaps surprisingly, in this effort the author makes use of the concept of ‘force multiplier’. This idea and its official applications have explanatory importance in considering the correlation between the post-Cold War phenomenal growth in the number of international non-governmental organizations and the emergence of the US as the sole, unchallenged superpower. Four moral constraints useful for morally assessing international activism are formulated and defended. The final outcome is an argument in favor of an overarching duty for any activist-minded Westerner to go local, while developing nations are urged to closely regulate, even criminalize, activities by international activists and ‘human rights organizations’ on their territory when not in solidarity or in support of local movements. The position defended, urging the normative primacy of local over international activism, also finds support in Immanuel Kant's Third Definitive Article for A Perpetual Peace.

  8. 75 FR 60141 - International Business Machines (IBM), Global Technology Services Delivery Division, Including On...

    Science.gov (United States)

    2010-09-29

    ... 25, 2010, applicable to workers of International Business Machines (IBM), Global Technology Services... hereby issued as follows: All workers of International Business Machines (IBM), Global Technology... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-74,164] International Business...

  9. 77 FR 17525 - Cinram Distribution, LLC, a Subsidiary of Cinram International Income Fund, Including On-Site...

    Science.gov (United States)

    2012-03-26

    ... International Income Fund had their wages reported through a separate unemployment insurance (UI) tax account..., a Subsidiary of Cinram International Income Fund, Including On-Site Leased Workers From Good People..., 2012, applicable to workers of Cinram Distribution, LLC, a subsidiary of Cinram International Income...

  10. Start of the international tokamak physics activity

    International Nuclear Information System (INIS)

    Campbell, D.

    2001-01-01

    This newsletter comprises a summary on the start of the International Tokamak Physics activity (ITPA) by Dr. D. Campbell, Chair of the ITPA Co-ordinating Committee. As the ITER EDA drew to a close, it became clear that it was desirable to establish a new mechanism in order to promote the continued development of the physics basis for burning plasma experiments and to preserve the invaluable collaborations between the major international fusion communities which had been established through the ITER physics expert groups. As a result of the discussions of the representatives of the European Union, Japan, the Russian Federation and the United States the agreed principles for conducting the International Tokamak Physics Activity (ITPA) were elaborated and ITPA topical physics groups were organized

  11. Alumni Activities : International Alumni Network for TUAS

    OpenAIRE

    Saarinen, Riikka-Maria

    2013-01-01

    Turku University of Applied Sciences is currently planning on creating an International Alumni Network for the former exchange students who had their exchange period at TUAS. In this thesis, alumni functions are divided into three sections, i.e. the purpose of the alumni, the activities of the alumni and the management of the communication of the alumni. The research of the alumni functions was conducted by introduction of alumni activities in general and introducing three examples of Amer...

  12. International Atomic Energy Agency. Highlights of activities

    International Nuclear Information System (INIS)

    Gillen, V.A.

    1991-09-01

    This document provides a brief, well-illustrated summary of the activities of the International Atomic Energy Agency in the months up to September 1991. Especially mentioned are the programmes to enhance the safety of nuclear power, from the study of nuclear reactors to assessing the radiological consequences of reactor accidents, and the areas of non-proliferation and safeguards

  13. International Atomic Energy Agency: Highlights of activities

    International Nuclear Information System (INIS)

    Gillen, A.

    1992-09-01

    This document provides a brief, well-illustrated summary of the activities of the International Atomic Energy Agency in the months up to September 1992. Especially mentioned are the programmes to enhance the safety of nuclear power, from the study of nuclear reactors to assessing the radiological consequences of reactor accidents, and the areas of non-proliferation and safeguards

  14. Health Promotion Behavior of Chinese International Students in Korea Including Acculturation Factors: A Structural Equation Model.

    Science.gov (United States)

    Kim, Sun Jung; Yoo, Il Young

    2016-03-01

    The purpose of this study was to explain the health promotion behavior of Chinese international students in Korea using a structural equation model including acculturation factors. A survey using self-administered questionnaires was employed. Data were collected from 272 Chinese students who have resided in Korea for longer than 6 months. The data were analyzed using structural equation modeling. The p value of final model is .31. The fitness parameters of the final model such as goodness of fit index, adjusted goodness of fit index, normed fit index, non-normed fit index, and comparative fit index were more than .95. Root mean square of residual and root mean square error of approximation also met the criteria. Self-esteem, perceived health status, acculturative stress and acculturation level had direct effects on health promotion behavior of the participants and the model explained 30.0% of variance. The Chinese students in Korea with higher self-esteem, perceived health status, acculturation level, and lower acculturative stress reported higher health promotion behavior. The findings can be applied to develop health promotion strategies for this population. Copyright © 2016. Published by Elsevier B.V.

  15. International Centre for Theoretical Physics: scientific activities in 1984

    International Nuclear Information System (INIS)

    1985-09-01

    A review of the scientific activities of the Centre, including workshops, research, and training-for-research is presented. The scientific program consists of seven main fields, Physics and Energy, Fundamental Physics, Physics and Technology, Physics of the Living State, Physics of the Environment, Physics and Development, and Mathematics. In addition to a brief description of each workshop, symposium, college, and meeting, tables summarizing the participation at ICTP activities are given. A list of preprints and internal reports issued in 1984 is included

  16. Do International Students Appreciate Active Learning in Lectures?

    Directory of Open Access Journals (Sweden)

    Mauricio Marrone

    2018-03-01

    Full Text Available Active learning has been linked with increased student motivation, engagement and understanding of course material. It promotes deep learning, helping to develop critical thinking and writing skills in students. Less well understood, however, are the responses of international students to active learning. Using social constructivist theory, the purpose of this study is to examine domestic and international student perceptions of active learning introduced into large undergraduate Accounting Information Systems lectures. Several active learning strategies were implemented over one semester and examined through the use of semi-structured interviews as well as pre- and post- implementation surveys. Our results suggest broad improvements for international students in student engagement and understanding of unit material when implementing active learning strategies. Other key implications include international student preference for active learning compared with passive learning styles, and that international students may receive greater benefits from active learning strategies than domestic students due to social factors. Based on these findings this paper proposes that educators should seek to implement active learning to better assist and integrate students of diverse backgrounds.

  17. 76 FR 2145 - International Paper Company, Franklin Pulp & Paper Mill, Including On-Site Leased Workers From...

    Science.gov (United States)

    2011-01-12

    ... Company, Franklin Pulp & Paper Mill, Including On-Site Leased Workers From Railserve, Franklin, VA..., applicable to workers and former workers of International Paper Company, Franklin Pulp & Paper Mill, Franklin... follows: All workers International Paper Company, Franklin Pulp & Paper Mill, including on-site leased...

  18. Ganymede's internal structure including thermodynamics of magnesium sulfate oceans in contact with ice

    Science.gov (United States)

    Vance, Steve; Bouffard, Mathieu; Choukroun, Mathieu; Sotin, Christophe

    2014-06-01

    The large icy moons of Jupiter contain vast quantities of liquid water, a key ingredient for life. Ganymede and Callisto are weaker candidates for habitability than Europa, in part because of the model-based assumption that high-pressure ice layers cover their seafloors and prevent significant water-rock interaction. Water-rock interactions may occur, however, if heating at the rock-ice interface melts the high pressure ice. Highly saline fluids would be gravitationally stable, and might accumulate under the ice due to upward migration, refreezing, and fractionation of salt from less concentrated liquids. To assess the influence of salinity on Ganymede's internal structure, we use available phase-equilibrium data to calculate activity coefficients and predict the freezing of water ice in the presence of aqueous magnesium sulfate. We couple this new equation of state with thermal profiles in Ganymede's interior-employing recently published thermodynamic data for the aqueous phase-to estimate the thicknesses of layers of ice I, III, V, and VI. We compute core and silicate mantle radii consistent with available constraints on Ganymede's mass and gravitational moment of inertia. Mantle radii range from 800 to 900 km for the values of salt and heat flux considered here (4-44 mW m-2 and 0 to 10 wt% MgSO4). Ocean concentrations with salinity higher than 10 wt% have little high pressure ice. Even in a Ganymede ocean that is mostly liquid, achieving such high ocean salinity is permissible for the range of likely S/Si ratios. However, elevated salinity requires a smaller silicate mantle radius to satisfy mass and moment-of-inertia constraints, so ice VI is always present in Ganymede's ocean. For lower values of heat flux, oceans with salinity as low as 3 wt% can co-exist with ice III. Available experimental data indicate that ice phases III and VI become buoyant for salinity higher than 5 wt% and 10 wt%, respectively. Similar behavior probably occurs for ice V at salinities

  19. Does Europe Include Japan? European Normativity in Japanese Attitudes towards International Law, 1854–1945

    Directory of Open Access Journals (Sweden)

    Urs Matthias Zachmann

    2014-01-01

    Full Text Available European normativity has been an epistemological problem for Japan throughout modernity (1868–1945. This essay discusses this problem in the case of international law by tracing its reception and application from the beginning, the opening- up of Japan in 1854, until the final demise of its imperialist project in 1945. During this period, Japan was the only non-Western great power in the hitherto all-European concert of powers. International law and the critique of European normativity played a central role in Japan’s ascent to power and confrontation with the West. In the first phase of reception between 1954 and 1905, Japanese attitudes towards international law were marked by an exceptional commitment to and acquiescence with the European standard, in line with Japan’s ambition to »leave Asia«. However, due to its strategic purposes, European normativity was more a means of political expediency than a matter of intrinsic conviction. Moreover, after the initial phase of receiving and practicing the principles of international law with considerable success, many Japanese began to feel a certain estrangement and inner reservation to European standards. Not until 1905, was Japan in a position to gradually challenge Europe. Thus, Japan’s interwar period (1905–1931 was an uneasy combination of outward compliance and inner reservation, a tension that Japan eventually resolved by withdrawing from Europe and trying to build its own autonomous sphere in East Asia after 1931. However, the example of Japanese international lawyers shows that in order to save international law from its ultranationalist critics and enemies, European normativity still remained the central cultural reference, albeit now in its revisionist variant (especially Soviet and Nazi German political thought and subject to a strategic re-interpretation. Thus, from the perspective of Japanese international lawyers, despite the Pan-Asianist pretenses of Japan’s official

  20. Should cryptocurrencies be included in the portfolio of international reserves held by central banks?

    Directory of Open Access Journals (Sweden)

    Winston Moore

    2016-12-01

    Full Text Available In most countries, the central bank is required to hold reserve assets as a means of providing credibility for the value of the fiat currency. These assets can be in the form of gold, foreign exchange or some other internationally recognised reserve asset and are held to permit the country to engage in international transactions. Within recent years, cryptocurrencies have been increasingly utilised for international transactions, and it is possible that the use of these cryptocurrencies might expand in the future. This paper therefore examines the potential role of digital currency balances as part of the portfolio of external assets held by a central bank. Using the case of Barbados, the paper also provides a simulation of the effect holding some proportion of their asset-base would have had on the stability of the foreign reserves as well as the return on the portfolio of assets.

  1. The Social Studies Should Include More Discussion of International Human Rights.

    Science.gov (United States)

    Torney, Judith V.

    1980-01-01

    Students need more exposure to the concept of human rights. They need to know The Universal Declaration of Human Rights and the subsequent covenants. Also, they need to know that substantial agreement exists in the international community about what constitutes human rights. (Author/KC)

  2. Current radiation protection activities of the International Atomic Energy Agency

    International Nuclear Information System (INIS)

    Webb, G.A.M.

    1996-01-01

    The International Atomic Energy Agency (IAEA) program of the Radiation Safety Section is described in this paper. The Section has two main components: (1) the development of consensus safety documentation and (2) the use of that documentation as the basis for assisting countries to deal safely with their applications of radiation and radioactivity. Main activities of the section are listed for each of these components. Activities include documentation, coordinated research programs, and assistance to developing countries. 14 tabs

  3. Burnout and Physical Activity in Minnesota Internal Medicine Resident Physicians

    Science.gov (United States)

    Olson, Shawn M.; Odo, Nnaemeka U.; Duran, Alisa M.; Pereira, Anne G.; Mandel, Jeffrey H.

    2014-01-01

    Background Regular physical activity plays an important role in the amelioration of several mental health disorders; however, its relationship with burnout has not yet been clarified. Objective To determine the association between achievement of national physical activity guidelines and burnout in internal medicine resident physicians. Methods A Web-based survey of internal medicine resident physicians at the University of Minnesota and Hennepin County Medical Center was conducted from September to October 2012. Survey measures included the Maslach Burnout Inventory-Human Services Survey and the International Physical Activity Questionnaire. Results Of 149 eligible residents, 76 (51.0%) completed surveys, which were used in the analysis. Burnout prevalence, determined by the Maslach Burnout Inventory, was 53.9% (41 of 76). Prevalence of failure to achieve US Department of Health and Human Services physical activity guidelines was 40.8% (31 of 76), and 78.9% (60 of 76) of residents reported that their level of physical activity has decreased since they began medical training. Residents who were able to meet physical activity guidelines were less likely to be burned out than their fellow residents (OR, 0.38, 95% CI 0.147–0.99). Conclusions Among internal medicine resident physicians, achievement of national physical activity guidelines appears to be inversely associated with burnout. Given the high national prevalence of burnout and inactivity, additional investigation of this relationship appears warranted. PMID:26140116

  4. International Year of Planet Earth - Activities and Plans in Mexico

    Science.gov (United States)

    Alaniz-Alvarez, S.; Urrutia-Fucugauchi, J.

    2007-12-01

    IYPE started as a joint initiative by UNESCO and IUGS with participation of several geosciences organizations, and has developed into a major program in geosciences with inclusion of national committees. In this presentation we focus on current activities and plans in our country, and in the international activities. IYPE activities have concentrated in publications and organization of conferences and meetings. A book series on Earth Science Experiments for Children has been defined, with the first books published on "Atmospheric Pressure and Free Fall of Objects" and "Light and Colors". Following books are on "Standing on Archimedes" and "Foucault and the Climate". Books are distributed free to school children, with more than 10,000 copies given of first volume. Other publications include the special issues of El Faro science magazine edited by the National University, with last issue published and distributed electronically and in hard copies this August. Special events include Conference of IYPE Executive Director presented during the International Day of Science Museums in late May in Science Museum Universum. This was followed by a Planet Earth Week in the University. Current plans include an electronic open-access publication, additional publications of the Planet Earth series, articles and special issues in journals and magazines, and events on selected themes from the IYPE science program, particularly on Megacities, Hazards, Resources and Life. The metropolitan area of Mexico City, with around 20 million inhabitants presents special challenges, being at high altitude within an active tectonic and volcanic area requiring major efforts in water supply, water control, rains and waste disposal and management. Involvement in international activities includes translation into Spanish of IYPE publications and the participation in programs and activities. In addition to activities in the different countries, we consider that IYPE should result in initiatives for

  5. Internal control activities in small Turkish companies

    Directory of Open Access Journals (Sweden)

    Ismail Bilgi

    2017-01-01

    Full Text Available The purpose of this paper is to present major outcomes from an empirical study concerning internal control activities in small Turkish companies, as to propose the improvement guidelines. Methods of analysis and synthesis, descriptive statistics, and statistical comparison were used. The collected data was processed with the help of the SPSS software. Тhe study is limited to organizations based in the European part of Turkey. Most of them operate in areas around large cities, such as Istanbul, Edirne, Kırklareli, and Tekirdağ. They employ on average 19-20 people and have a turnover of about TRY 3 million (≈€715,000, https://sdw.ecb.europa.eu on average. The survey concentrates mainly on small family businesses, which have been present on the market for more than ten years, with managers of good education and other characteristics that presuppose availability of internal control systems. The research results were used to compile main points of a SWOT analysis, as a part of the broader effort to help modernizing the internal control system in Turkish small businesses.

  6. 76 FR 81986 - Honeywell International, Inc., Automation and Control Solutions Division, Including On-Site...

    Science.gov (United States)

    2011-12-29

    ..., Inc., Automation and Control Solutions Division, Including On-Site Leased Workers From Manpower...., Automation and Control Solutions Division. The Department has determined that these workers were sufficiently...., Automation and Control Solutions Division, including on-site leased workers from Manpower, Spherion...

  7. Internal friction and ultrasonic attenuation in solids, including high Tc superconductors

    International Nuclear Information System (INIS)

    Magalas, L.B.; Gorczyca, S.

    1993-01-01

    This volume contains seven invited papers and about eighty refereed contributions from the main sessions of the Sixth European Conference on Internal Friction and Ultrasonic Attenuation in Solids (ECIFUAS-6) held at the Academy of Mining and Metallurgy (Akademia Gorniczo-Hutnicza, AGH) in Krakow, Poland, 5-7 September, 1991. In addition, this volume contains six invited lectures and eight contributed papers presented at the Workshop on High Tc Superconductors on 5 September, 1991. Together these documents constitute the Proceedings of the ECIFUAS-6 Conference. A total of 140 scientists from 20 countries participated in the Conference. The programme of the Conference and the Workshop consisted of 16 invidet papers and 119 contributed papers. 107 papers were presented during 8 poster sessions. (orig.)

  8. International Centre for Theoretical Physics: Scientific activities in 1986

    International Nuclear Information System (INIS)

    1987-10-01

    A review of the scientific activities of the Centre in 1986, including workshops, research and training-for-research is presented. The scientific program consists of eight main fields: Physics and Energy, Fundamental Physics, Physics of Condensed Matter, Applied Physics, Mathematics, Physics of the Environment and of National Resources, Physics of the Living State, Physics and Development. In addition to a brief description of each workshop, symposium, college and meeting, tables summarizing the participation of ICTP activities are given. A list of preprints and internal reports issued in 1986 is included

  9. International Centre for Theoretical Physics. Scientific activities in 1987

    International Nuclear Information System (INIS)

    1988-12-01

    A review of the scientific activities of the ICTP Trieste in 1987, including workshops, research and training for research is presented. The scientific program consists of eight main fields: fundamental physics, condensed matter, atomic and molecular physics, mathematics, physics and energy, physics and environment, applied physics and high technology, physics and development. In addition to a brief description of each workshop, symposium, college, meeting and activity or project sponsored by ICTP, a list of preprints and internal reports issued in 1987 is included. Tabs

  10. International Centre for Theoretical Physics. Scientific activities in 1985

    International Nuclear Information System (INIS)

    1986-08-01

    A review of the scientific activities of the Centre, including workshops, research, and training-for-research is presented. The scientific program consists of ten main fields, Physics and Energy, Fundamental Physics, Physics of Condensed Matter, Applied Physics, Physics of the Living State, Physics of the Environment, Mathematics, Physics Teaching, Experimental Physics Training, and Physics and Development. In addition to a brief description of each workshop, symposium, college, and meeting, tables summarizing the participation at ICTP activities are given. A list of preprints and internal reports issued in 1985 is included

  11. Should we include avoidance of deforestation in the international response to climate change?

    Energy Technology Data Exchange (ETDEWEB)

    Schlamadinger, B. [Joanneum Research, Graz (Austria); Ciccarese, L. [Italian Agency for Environmental Protection and Technical Services, Rome (Italy); Dutschke, M. [Hamburg Institute of International Economics, Hamburg (Germany); Fearnside, P.M. [Department of Ecology, National Institute for Amazonian Research INPA, Belem, Para (Brazil); Brown, S. [Winrock International, Little Rock, Arkansas (United States); Murdiyarso, D. [Center for International Forestry Research, Jakarta (Indonesia)

    2005-07-01

    Global deforestation and forest degradation rates have a significant impact on the accumulation of greenhouse gases (GHGs) in the atmosphere. The Food and Agriculture Organization (FAO) estimated that during the 1990's 16.1 million hectares per year were affected by deforestation, most of them in the tropics. The Intergovernmental Panel on Climate Change (IPCC) calculated that, for the same period, the contribution of land-use changes to GHG accumulation into the atmosphere was 1.6{+-}0.8 Giga (1G=109) tonnes of carbon per year, a quantity that corresponds to 25% of the total annual global emissions of GHGs. The United Nations Framework Convention on Climate Change (UNFCCC), in recognising climate change as a serious threat, urged counties to take up measures to enhance and conserve ecosystems such as forests that act as reservoirs and sinks of GHGs. The Kyoto Protocol (KP), adopted in 1997, complements the UNFCCC by providing an enforceable agreement with quantitative targets for reducing GHG emissions. For fulfilling their emission-limitation commitments under the KP, industrialized countries (listed in the KP's Annex I) can use land-based activities, such as reducing deforestation, establishing new forests (afforestation and reforestation) and other vegetation types, managing agricultural and forestlands in a way that the 'carbon sink' is maximized. Annex I countries may also claim credit for carbon sequestration in developing countries by afforestation and reforestation (AR) through the Clean Development Mechanism (CDM), one of the 'Kyoto Mechanisms' that allow countries to achieve reductions where it is economically efficient to do so. For the period 2008-2012, forestry activities under the CDM have been restricted to afforestation and reforestation on areas that were not forested in 1990. In addition, CDM projects must lead to emission reductions or net carbon uptake additional to what would have occurred without the CDM funding

  12. Crystalline and Crystalline International Disposal Activities

    Energy Technology Data Exchange (ETDEWEB)

    Viswanathan, Hari S. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Chu, Shaoping [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Dittrich, Timothy M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Hyman, Jeffrey De' Haven [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Karra, Satish [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Makedonska, Nataliia [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Reimus, Paul William [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-03-06

    This report presents the results of work conducted between September 2015 and July 2016 at Los Alamos National Laboratory in the crystalline disposal and crystalline international disposal work packages of the Used Fuel Disposition Campaign (UFDC) for DOE-NE’s Fuel Cycle Research and Development program. Los Alamos focused on two main activities during this period: Discrete fracture network (DFN) modeling to describe flow and radionuclide transport in complex fracture networks that are typical of crystalline rock environments, and a comprehensive interpretation of three different colloid-facilitated radionuclide transport experiments conducted in a fractured granodiorite at the Grimsel Test Site in Switzerland between 2002 and 2013. Chapter 1 presents the results of the DFN work and is divided into three main sections: (1) we show results of our recent study on the correlation between fracture size and fracture transmissivity (2) we present an analysis and visualization prototype using the concept of a flow topology graph for characterization of discrete fracture networks, and (3) we describe the Crystalline International work in support of the Swedish Task Force. Chapter 2 presents interpretation of the colloidfacilitated radionuclide transport experiments in the crystalline rock at the Grimsel Test Site.

  13. International Atomic Energy Agency activities in decommissioning

    International Nuclear Information System (INIS)

    Reisenweaver, D W.; )

    2005-01-01

    Full text: The International Atomic Energy Agency (IAEA) has been addressing the safety and technical issues of decommissioning for over 20 years, but their focus has been primarily on planning. Up to know, the activities have been on an ad hoc basis and sometimes, important issues have been missed. A new Action Plan on the Decommissioning of Nuclear Facilities has recently been approved by the Agency's board of Governors which will focus the Agency's efforts and ensure that our Member States' concerns are addressed. The new initiatives associated with this Action Plan will help ensure that decommissioning activities in the future are performed in a safe and coherent manner. The International Atomic Energy Agency (IAEA) has been preparing safety and technical documents concerning decommissioning since the mid-1980's. There have been over 30 documents prepared that provide safety requirements, guidance and supporting technical information. Many of these documents are over 10 years old and need updating. The main focus in the past has been on planning for decommissioning. During the past five years, a set of Safety Standards have been prepared and issued to provide safety requirements and guidance to Member States. However, decommissioning was never a real priority with the Agency, but was something that had to be addressed. To illustrate this point, the first requirements documents on decommissioning were issued as part of a Safety Requirements [1] on pre-disposal management of radioactive waste. It was felt that decommissioning did not deserve its own document because it was just part of the normal waste management process. The focus was mostly on waste management. The Agency has assisted Member States with the planning process for decommissioning. Most of these activities have been focused on nuclear power plants and research reactors. Now, support for the decommissioning of other types of facilities is being requested. The Agency is currently providing technical

  14. 75 FR 26794 - International Paper Company Franklin Pulp & Paper Mill Including On-Site Leased Workers From...

    Science.gov (United States)

    2010-05-12

    ... Company Franklin Pulp & Paper Mill Including On-Site Leased Workers From Railserve, Franklin, VA; Amended... workers of International Paper Company, Franklin Pulp & Paper Mill, Franklin, Virginia. The notice was... Pulp & Paper Mill. The Department has determined that these workers were sufficiently under the control...

  15. 7 CFR 981.441 - Credit for market promotion activities, including paid advertising.

    Science.gov (United States)

    2010-01-01

    ... promotion activities, including paid advertising. (a) In order for a handler to receive credit for his/her... 7 Agriculture 8 2010-01-01 2010-01-01 false Credit for market promotion activities, including paid advertising. 981.441 Section 981.441 Agriculture Regulations of the Department of Agriculture (Continued...

  16. INTERNATIONAL MARKETING ACTIVITIES OF MULTINATIONAL COMPANIES IN CONDITIONS OF INSTABILITY

    OpenAIRE

    N. V. Lyasnikov; Yu. V. Lyasnikova

    2016-01-01

    This article describes the conceptual basis for the formation of international marketing, the characteristic of the main exit strategies on the world market, revealed features of international marketing that national companies are obliged to take into account the examples of international marketing strategies of international companies such as Apple, Google, Nike, the Russian company Natura Siberica.The purpose of this paper is to analyze the international marketing activities of multinationa...

  17. Macroenvironmental factors including GDP per capita and physical activity in Europe.

    Science.gov (United States)

    Cameron, Adrian J; Van Stralen, Maartje M; Kunst, Anton E; Te Velde, Saskia J; Van Lenthe, Frank J; Salmon, Jo; Brug, Johannes

    2013-02-01

    Socioeconomic inequalities in physical activity at the individual level are well reported. Whether inequalities in economic development and other macroenvironmental variables between countries are also related to physical activity at the country level is comparatively unstudied. We examined the relationship between country-level data on macroenvironmental factors (gross domestic product (GDP) per capita, public sector expenditure on health, percentage living in urban areas, and cars per 1000 population) with country-level physical activity prevalence obtained from previous pan-European studies. Studies that assessed leisuretime physical activity (n = 3 studies including 27 countries in adults, n = 2 studies including 28 countries in children) and total physical activity (n = 3 studies in adults including 16 countries) were analyzed separately as were studies among adults and children. Strong and consistent positive correlations were observed between country prevalence of leisure-time physical activity and country GDP per capita in adults (average r = 0.70; all studies, P G 0.05). In multivariate analysis, country prevalence of leisure-time physical activity among adults remained associated with country GDP per capita (two of three studies) but not urbanization or educational attainment. Among school-age populations, no association was found between country GDP per capita and country prevalence of leisure-time physical activity. In those studies that assessed total physical activity (which also includes occupational and transport physical activity), no association with country GDP per capita was observed. Clear differences in national leisure-time physical activity levels throughout Europe may be a consequence of economic development. Lack of economic development of some countries in Europe may make increasing leisure-time physical activity more difficult. Further examination of the link between country GDP per capita and national physical activity levels (across

  18. Optimal Design and Real Time Implementation of Autonomous Microgrid Including Active Load

    OpenAIRE

    Mohamed A. Hassan; Muhammed Y. Worku; Mohamed A. Abido

    2018-01-01

    Controller gains and power-sharing parameters are the main parameters affect the dynamic performance of the microgrid. Considering an active load to the autonomous microgrid, the stability problem will be more involved. In this paper, the active load effect on microgrid dynamic stability is explored. An autonomous microgrid including three inverter-based distributed generations (DGs) with an active load is modeled and the associated controllers are designed. Controller gains of the inverters ...

  19. International Atomic Energy Agency. Highlights of activities. September 1993

    International Nuclear Information System (INIS)

    Gillen, V.A.

    1993-09-01

    This document describes the most important activities of the International Atomic Energy Agency during the period September 1992 - September 1993, in particular in the following areas: (i) nuclear power; (ii) nuclear fuel cycle; (iii) radioactive waste management; (iv) comparative assessment of energy sources; (v) IAEA laboratory activities; (vi) nuclear applications in the food industry and in agriculture; (vii) human health applications of nuclear techniques, especially in the treatment and prevention of diseases and in the analysis of health problems related to the environment; (viii) industry and earth sciences; (ix) physical and chemical sciences; (x) radiation protection; (xi) safety of nuclear installations; (xii) safeguards and non-proliferation activities; (xiii) activities in the area of public and technical information such as the International Nuclear Information System (INIS) and other IAEA computerized databases and reference systems, the publication Nuclear Fusion, a monthly scientific journal of articles on thermonuclear fusion research and development, and the organization of meetings on atomic energy; and (xiv) a description of the Agency's technical assistance activities, including financial data

  20. International Centre for Theoretical Physics, Trieste. Scientific activities in 1995

    International Nuclear Information System (INIS)

    1996-10-01

    The annual report of the International Centre for Theoretical Physics from Trieste for 1995 contains three parts. Part 1 includes statistical data on the main activities of the Centre. Part 2 presents the scientific programme in various fields (Physics of Condensed Matter, Physics of High and Intermediate Energies, Mathematics, Physics and Energy, Physics of the Environment, Physics of Living State, Applied Physics and Miscellaneous) as well as other activities such as diploma course, long-term scientific visitors, associate members and federation arrangements, training and research at Italian laboratories, external activities, books and equipment donation programme, awards, and meetings hosted. Part 3 lists the publications issued in 1995 and gives information about the library of the Centre. 6 tabs

  1. International Centre for Theoretical Physics, Trieste. Scientific activities in 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-10-01

    The annual report of the International Centre for Theoretical Physics from Trieste for 1995 contains three parts. Part 1 includes statistical data on the main activities of the Centre. Part 2 presents the scientific programme in various fields (Physics of Condensed Matter, Physics of High and Intermediate Energies, Mathematics, Physics and Energy, Physics of the Environment, Physics of Living State, Applied Physics and Miscellaneous) as well as other activities such as diploma course, long-term scientific visitors, associate members and federation arrangements, training and research at Italian laboratories, external activities, books and equipment donation programme, awards, and meetings hosted. Part 3 lists the publications issued in 1995 and gives information about the library of the Centre. 6 tabs.

  2. International Centre for Theoretical Physics: scientific activities in 1982

    International Nuclear Information System (INIS)

    1983-08-01

    Research and training-for-research were carried out in the following areas: physics and energy (nuclear physics, solar energy), physics and frontiers of knowledge (elementary particles and fundamental theory), physics of the living state, physics and technology (condensed matter physics), applicable mathematics and planning models (applicable mathematics, mathematical ecology), physics of the environment and of natural resources (geomagnetism, ionospheric and magnetospheric physics, atmospheric physics), and physics and development. Activities included both research at the Centre and a number of workshops and symposia. The subjects treated are briefly summarized, and references to preprints and internal reports are given

  3. Adaptation of the international physical activity questionnarie for the elderly

    Directory of Open Access Journals (Sweden)

    Tânia R. Bertoldo Benedetti

    2010-09-01

    Full Text Available The International Physical Activity Questionnaire (IPAQ estimates the weekly energy expenditure for physical activities (PA. This instrument was validated for use with Brazilian older adults. The need to adapt the structure and application of the IPAQ arose from the difficulties of older adults to correctly measure the number of days, time and intensity of PA (domains during a normal week and the difficulties encountered by the interviewers in field research. The adapted IPAQ consists of five domains and 15 questions and is applied by interview because of the low educational level of Brazilian older adults. The instrument is applied in its long form to permit better discrimination of PA in each domain and refers to a normal week to help recall morning, afternoon and evening activities. In addition, it includes details about mild, moderate and vigorous intensity. The training of the interviewers is fundamental. The report of the IPAQ adapted for older adults should be delivered in minutes per week and should use the classification active (≤ 150 min/week. The IPAQ adapted for older adults is an international instrument that is valid for the Brazilian elderly population. The instrument is a noninvasive easily applied method of low cost that reaches large population groups, among other advantages.

  4. Crystalline and Crystalline International Disposal Activities

    Energy Technology Data Exchange (ETDEWEB)

    Viswanathan, Hari S. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Chu, Shaoping [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Reimus, Paul William [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Makedonska, Nataliia [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Hyman, Jeffrey De' Haven [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Karra, Satish [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Dittrich, Timothy M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-12-21

    This report presents the results of work conducted between September 2014 and July 2015 at Los Alamos National Laboratory in the crystalline disposal and crystalline international disposal work packages of the Used Fuel Disposition Campaign (UFDC) for DOE-NE’s Fuel Cycle Research and Development program.

  5. Unified theory of dislocation motion including thermal activation and inertial effects

    International Nuclear Information System (INIS)

    Isaac, R.D.; Granato, A.V.

    1979-01-01

    Transition-state rate theory has generally been used to explain the temperature dependence of the flow stress of a crystal. However, the existence of a change in the flow stress during the superconducting transition indicates the presence of inertial effects in which dislocations overcome obstacles mechanically rather than thermally. It is shown here that the thermally activated and the inertial overcoming of obstacles are not unrelated but can both be derived from principles of stochastic motion. This leads to a theory of dislocation motion that includes both thermal activation and inertial effects. It is also shown that a distribution of activation energies must be considered to account for the experimental data

  6. Motivating the Study of International Trade: A Classroom Activity

    Science.gov (United States)

    Jensen, Sherry

    2016-01-01

    In this article, the author describes a classroom activity for use in introductory economics courses to motivate the study of international trade. The learning activity highlights the importance of international trade in students' everyday lives by having students inventory their on-hand belongings and identify where the items were manufactured.…

  7. International Association for Promoting Geoethics (IAPG): an update on activities

    Science.gov (United States)

    Di Capua, Giuseppe; Bobrowsky, Peter; Kieffer, Susan; Peppoloni, Silvia; Tinti, Stefano

    2016-04-01

    The International Association for Promoting Geoethics (IAPG: http://www.geoethics.org) was founded on August 2012 to unite global geoscientists to raise the awareness of the scientific community regarding the importance of the ethical, social and cultural implications of geoscience research, education, and practice. IAPG is an international, multidisciplinary and scientific platform for discussion on ethical problems and dilemmas in Earth Sciences, promoting geoethical themes through scientific publications and conferences, strengthening the research base on geoethics, and focusing on case-studies as models for the development of effective and operative strategies. IAPG is legally recognized as a not-for-profit organization. It is a non-governmental, non-political, non-party institution, at all times free from racial, gender, religious or national prejudices. Its network continues to grow with more than 900 members in 103 countries, including 20 national sections. IAPG operates exclusively through donations and personal funds of its members. The results achieved since inception have been recognized by numerous international organizations. In particular, IAPG has obtained the status of affiliated organization by the International Union of Geological Sciences (IUGS), American Geosciences Institute (AGI), Geological Society of America (GSA), and the Geological Society of London (GSL). IAPG has enlarged its official relationships also through agreements on collaboration with other organizations, such as the American Geophysical Union (AGU), EuroGeoSurveys (EGS), European Federation of Geologists (EFG), Association of Environmental & Engineering Geologists (AEG), International Geoscience Education Organisation (IGEO), African Association of Women in Geosciences (AAWG), and others. IAPG considers publications as an indispensable activity to strengthen geoethics from a scientific point of view, so members are active in the publication of articles and editing of books on

  8. The relationship between the TMJ internal derangement state including rotational displacement and perforation and the clinical characteristics

    International Nuclear Information System (INIS)

    Jeong, Hwan Seok; You Dong Soo

    1998-01-01

    This study was designed to reveal the correlationship between the internal derangement state of TMJ and clinical characteristics including pain and mandibular dysfuntion. One hundred and twenty five subjects with TMJ signs and symptoms were chosen for two years. The level of pain and mandibular dysfuntion were evaluated by Visual Analog Scale (VAS) and Craniomandibular Index (CMI). The diagnostic categories of TMJ internal derangement were determined by arthrography and they included normal disc position, anterior disc displacement with reduction (ADDR), rotational disc displacement with reduction (RDDR), andterior disc displacement without reduction (ADDNR), and rotational disc displacement without reduction (RDDNR). Also disc perforation was used as a criteria to divide the diagnostic subgroups. The obtained results were as follows ; 1. The patient distribution of each group was 5 in normal disc position (4%), 40 in ADDR (32%), 30 in RDDR (24%), 34 in ADDNR (27%), and 16 in RDDNR (13%). 2. Perforation was observed in 8% of ADDR, 10% of RDDR, 32% of ADDNR, and 19% of RDDNR. 3. CMI of perforation group was higher than that of reduction or normal group(p 0.05).

  9. Triple Active Antiretroviral Regimen Including Enfuvirtide Via the Biojector is Effective and Safe

    Directory of Open Access Journals (Sweden)

    Mona Loutfy

    2007-01-01

    Full Text Available For full HIV virological suppression, three fully active antiretroviral agents are required. New drug classes should be included to ensure that agents are fully active. The addition of enfuvirtide and efavirenz to the present patient’s new antiretroviral regimen ensured that two fully active agents were in use in the setting of a moderate degree of nucleoside resistance and a high level of protease resistance, and where non-nucleoside reverse transcriptase inhibitors were still fully active. Both viral load and CD4 count responded favourably to this regimen. The patient received support from physicians and clinic staff in the introduction and use of enfuvirtide. To reduce injection site reactions, a needle-free injection system (Biojector proved effective.

  10. International Atomic Energy Agency: activities in Malaysia

    Energy Technology Data Exchange (ETDEWEB)

    Hayati, Ainul [Nuclear Energy Unit, Bangi, Selangor (Malaysia)

    1994-12-31

    The two main IAEA activities participated by Malaysia - technical cooperation programme (TC) and regional cooperative agreement programme (RCA/IAEA AND IAEA/RCA/UNDP). This article highlighted some of the IAEA technical cooperation activities in Malaysia (i.e. Medicine, Agriculture, Industry, Strategic, Social Science), assistance, funding and contribution made by Malaysia to the IAEA since 1989.

  11. International Atomic Energy Agency: activities in Malaysia

    International Nuclear Information System (INIS)

    Ainul Hayati

    1994-01-01

    The two main IAEA activities participated by Malaysia - technical cooperation programme (TC) and regional cooperative agreement programme (RCA/IAEA AND IAEA/RCA/UNDP). This article highlighted some of the IAEA technical cooperation activities in Malaysia (i.e. Medicine, Agriculture, Industry, Strategic, Social Science), assistance, funding and contribution made by Malaysia to the IAEA since 1989

  12. Peptidase inhibitors reduce opiate narcotic withdrawal signs, including seizure activity, in the rat.

    Science.gov (United States)

    Pinsky, C; Dua, A K; LaBella, F S

    1982-07-15

    Narcotic withdrawal was precipitated by administration of naloxone in a low dose at 2 h after the final dose of morphine in a 9-day dependency-inducing schedule. Withdrawal was characterized by leaps, increased nocifensor activity and by cerebral cortical epileptiform activity, the latter not generally reported to be prominent in narcotic withdrawal. Single large doses of morphine did not provoke epileptiform activity at 2 h postinjection but did induce an acute opioid dependency wherein a moderately high dose of naloxone, ineffective in non-dependent rats, provoked upward leaping and electrocortical epileptiform activity. Pretreatment of the 9-day dependent rats with peptidase inhibitors, administered intracerebroventricularly, significantly reduced withdrawal severity including the epileptiform activity. We propose that peptidase inhibitors protect certain species of endogenous opioids and/or other neuropeptides that tend to suppress expression of the narcotic withdrawal syndrome. Furthermore, our findings suggest that epileptiform activity is a nascent form of cerebral activity hitherto largely unnoticed in narcotic withdrawal and that neuropeptides may be involved in certain epileptic states.

  13. Design of a high-lift experiment in water including active flow control

    International Nuclear Information System (INIS)

    Beutel, T; Schwerter, M; Büttgenbach, S; Leester-Schädel, M; Sattler, S; El Sayed, Y; Radespiel, R; Zander, M; Sinapius, M; Wierach, P

    2014-01-01

    This paper describes the structural design of an active flow-control experiment. The aim of the experiment is to investigate the increase in efficiency of an internally blown Coanda flap using unsteady blowing. The system uses tailor-made microelectromechanical (MEMS) pressure sensors to determine the state of the oncoming flow and an actuated lip to regulate the mass flow and velocity of a stream near a wall over the internally blown flap. Sensors and actuators are integrated into a highly loaded system that is extremely compact. The sensors are connected to a bus system that feeds the data into a real-time control system. The piezoelectric actuators using the d 33 effect at a comparable low voltage of 120 V are integrated into a lip that controls the blowout slot height. The system is designed for closed-loop control that efficiently avoids flow separation on the Coanda flap. The setup is designed for water-tunnel experiments in order to reduce the free-stream velocity and the system’s control frequency by a factor of 10 compared with that in air. This paper outlines the function and verification of the system’s main components and their development. (technical note)

  14. International Project Management Committee: Overview and Activities

    Science.gov (United States)

    Hoffman, Edward

    2010-01-01

    This slide presentation discusses the purpose and composition of the International Project Management Committee (IMPC). The IMPC was established by members of 15 space agencies, companies and professional organizations. The goal of the committee is to establish a means to share experiences and best practices with space project/program management practitioners at the global level. The space agencies that are involved are: AEB, DLR, ESA, ISRO, JAXA, KARI, and NASA. The industrial and professional organizational members are Comau, COSPAR, PMI, and Thales Alenia Space.

  15. The International Atomic Energy Agency: activities and relationship with Mexico

    International Nuclear Information System (INIS)

    Abud Osuna, Javier.

    1987-01-01

    Legal and political studies on the activities of the IAEA infer that the pacific uses of nuclear energy become more significant every day in the ambit of international relationships. The studies analyze as a whole relationships among member states. The first part is divided into four chapters, starting with the background and creation of the agency, its structure, statutes, amendments and the performance of its main organisms. It continues to describe mechanisms and programmes carried out, including cooperation agreements between the IAEA and other specialized organizations in the United Nations. It ends up with the IAEA performance resulting from different treaties. The second part examines Mexican norms on nuclear matter as well as relationships between Mexico and the IAEA. It demonstrates that achievements in the Agency have been possible because of the establishment of an international cooperation basis, which avoids duplicity of actions. The conclusions recommend joint efforts from both the developed and the developing countries in the following: a) to imbue public opinion with the goodness of nuclear energy; b) to discourage the construction and operation of nuclear installations; c) to unify national standards on nuclear safety and control; d) to decrease export restrictions, based on safeguards; e) to promote internal nuclear research in Mexico or throught regional integration agreements, with technical assistance and support from the IAEA. (author)

  16. En bloc resection of skull base tumor including internal carotid artery. Preoperative evaluation of cerebral blood flow

    International Nuclear Information System (INIS)

    Okamoto, Yoshitaka; Matsuzaki, Zensei; Kamijo, Atsushi; Ogino, Jun; Nagaseki, Yoshishige; Nukui, Hideaki; Yokomizo, Michinori; Togawa, Kiyoshi

    1998-01-01

    Carotid artery resection yields a possibility of cure in patients with advanced head and neck carcinoma involving the carotid artery. However, the criteria for the identification of those who are vulnerable to neurologic injury after resection have not been established. Interposition graft covered with a well-vascularized flap could minimize the rate of perioperative morbidity. Particularly, when an extensive resection of the skull base including carotid artery and sigmoid vein, is planned, extracranial-intracranial bypass should be considered to minimize the risks of neurologic morbidity, even if preresection positron emission tomography during balloon test occlusion of internal carotid artery suggested the adequacy of hemispheric collateral blood flow. In these cases, the temporary occlusion of the carotid artery is not an accurate prediction of the morbidity after permanent occlusion. (author)

  17. International Collaboration Activities on Engineered Barrier Systems

    Energy Technology Data Exchange (ETDEWEB)

    Jove-Colon, Carlos F. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2016-08-31

    The Used Fuel Disposition Campaign (UFDC) within the DOE Fuel Cycle Technologies (FCT) program has been engaging in international collaborations between repository R&D programs for high-level waste (HLW) disposal to leverage on gathered knowledge and laboratory/field data of near- and far-field processes from experiments at underground research laboratories (URL). Heater test experiments at URLs provide a unique opportunity to mimetically study the thermal effects of heat-generating nuclear waste in subsurface repository environments. Various configurations of these experiments have been carried out at various URLs according to the disposal design concepts of the hosting country repository program. The FEBEX (Full-scale Engineered Barrier Experiment in Crystalline Host Rock) project is a large-scale heater test experiment originated by the Spanish radioactive waste management agency (Empresa Nacional de Residuos Radiactivos S.A. – ENRESA) at the Grimsel Test Site (GTS) URL in Switzerland. The project was subsequently managed by CIEMAT. FEBEX-DP is a concerted effort of various international partners working on the evaluation of sensor data and characterization of samples obtained during the course of this field test and subsequent dismantling. The main purpose of these field-scale experiments is to evaluate feasibility for creation of an engineered barrier system (EBS) with a horizontal configuration according to the Spanish concept of deep geological disposal of high-level radioactive waste in crystalline rock. Another key aspect of this project is to improve the knowledge of coupled processes such as thermal-hydro-mechanical (THM) and thermal-hydro-chemical (THC) operating in the near-field environment. The focus of these is on model development and validation of predictions through model implementation in computational tools to simulate coupled THM and THC processes.

  18. International Collaboration Activities in Different Geologic Disposal Environments

    International Nuclear Information System (INIS)

    Birkholzer, Jens

    2015-01-01

    This report describes the current status of international collaboration regarding geologic disposal research in the Used Fuel Disposition (UFD) Campaign. Since 2012, in an effort coordinated by Lawrence Berkeley National Laboratory, UFD has advanced active collaboration with several international geologic disposal programs in Europe and Asia. Such collaboration allows the UFD Campaign to benefit from a deep knowledge base with regards to alternative repository environments developed over decades, and to utilize international investments in research facilities (such as underground research laboratories), saving millions of R&D dollars that have been and are being provided by other countries. To date, UFD's International Disposal R&D Program has established formal collaboration agreements with five international initiatives and several international partners, and national lab scientists associated with UFD have conducted specific collaborative R&D activities that align well with its R&D priorities.

  19. International Collaboration Activities in Different Geologic Disposal Environments

    Energy Technology Data Exchange (ETDEWEB)

    Birkholzer, Jens [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2015-09-01

    This report describes the current status of international collaboration regarding geologic disposal research in the Used Fuel Disposition (UFD) Campaign. Since 2012, in an effort coordinated by Lawrence Berkeley National Laboratory, UFD has advanced active collaboration with several international geologic disposal programs in Europe and Asia. Such collaboration allows the UFD Campaign to benefit from a deep knowledge base with regards to alternative repository environments developed over decades, and to utilize international investments in research facilities (such as underground research laboratories), saving millions of R&D dollars that have been and are being provided by other countries. To date, UFD’s International Disposal R&D Program has established formal collaboration agreements with five international initiatives and several international partners, and national lab scientists associated with UFD have conducted specific collaborative R&D activities that align well with its R&D priorities.

  20. Survey indicated that core outcome set development is increasingly including patients, being conducted internationally and using Delphi surveys.

    Science.gov (United States)

    Biggane, Alice M; Brading, Lucy; Ravaud, Philippe; Young, Bridget; Williamson, Paula R

    2018-02-17

    There are numerous challenges in including patients in a core outcome set (COS) study, these can vary depending on the patient group. This study describes current efforts to include patients in the development of COS, with the aim of identifying areas for further improvement and study. Using the COMET database, corresponding authors of COS projects registered or published from 1 January 2013 to 2 February 2017 were invited via a personalised email to participate in a short online survey. The survey and emails were constructed to maximise the response rate by following the academic literature on enhancing survey responses. Personalised reminder emails were sent to non-responders. This survey explored the frequency of patient input in COS studies, who was involved, what methods were used and whether or not the COS development was international. One hundred and ninety-two COS developers were sent the survey. Responses were collected from 21 February 2017 until 7 May 2017. One hundred and forty-six unique developers responded, yielding a 76% response rate and data in relation to 195 unique COSs (as some developers had worked on multiple COSs). Of focus here are their responses regarding 162 COSs at the published, completed or ongoing stages of development. Inclusion of patient participants was indicated in 87% (141/162) of COSs in the published completed or ongoing stages and over 94% (65/69) of ongoing COS projects. Nearly half (65/135) of COSs included patient participants from two or more countries and 22% (30/135) included patient participants from five or more countries. The Delphi survey was reported as being used singularly or in combination with other methods in 85% (119/140) of projects. Almost a quarter (16/65) of ongoing studies reported using a combination of qualitative interviews, Delphi survey and consensus meeting. These findings indicated that the Delphi survey is the most popular method of facilitating patient participation, while the combination of

  1. Optimal Design and Real Time Implementation of Autonomous Microgrid Including Active Load

    Directory of Open Access Journals (Sweden)

    Mohamed A. Hassan

    2018-05-01

    Full Text Available Controller gains and power-sharing parameters are the main parameters affect the dynamic performance of the microgrid. Considering an active load to the autonomous microgrid, the stability problem will be more involved. In this paper, the active load effect on microgrid dynamic stability is explored. An autonomous microgrid including three inverter-based distributed generations (DGs with an active load is modeled and the associated controllers are designed. Controller gains of the inverters and active load as well as Phase Locked Loop (PLL parameters are optimally tuned to guarantee overall system stability. A weighted objective function is proposed to minimize the error in both measured active power and DC voltage based on time-domain simulations. Different AC and DC disturbances are applied to verify and assess the effectiveness of the proposed control strategy. The results demonstrate the potential of the proposed controller to enhance the microgrid stability and to provide efficient damping characteristics. Additionally, the proposed controller is compared with the literature to demonstrate its superiority. Finally, the microgrid considered has been established and implemented on real time digital simulator (RTDS. The experimental results validate the simulation results and approve the effectiveness of the proposed controllers to enrich the stability of the considered microgrid.

  2. Transforming Internal Activities of Business Process Models to Services Compositions

    NARCIS (Netherlands)

    Dirgahayu, Teduh; Quartel, Dick; van Sinderen, Marten J.; Mostefaoui, S.K.; Maamar, Z.; Ferreira Pires, L.; Hammoudi, S.; Rinderle-Ma, S.; Sadiq, S.; Schulz, K.

    As a service composition language, BPEL imposes as constraint that a business process model should consist only of activities for interacting with other business processes. BPEL provides limited support for implementing internal activities, i.e. activities that are performed by a single business

  3. Reliability and validity of international physical activity questionnaire ...

    African Journals Online (AJOL)

    The International Physical Activity Questionnaire (IPAQ), a standardised method for assessing physical activity, has been tested at 14 centres in 12 countries on adults aged 18 to 65 years. However, there is no standardised instrument to determine levels of physical activity amongst Malay-speaking adults in Malaysia.

  4. Presentation of the decay data group activities at LPRI. (Links with international evaluation works)

    International Nuclear Information System (INIS)

    Be, M.M.

    1999-01-01

    The activities of the Primary Ionizing Radiation Laboratory (LPRI) which is affiliated with the French National Bureau of Metrology (BNM), include evaluation of decay data, absolute activity measurements, X- and gamma-ray spectrometry, development of new measuring techniques, etc. The following three activities in the field of decay data evaluation are briefly presented: NUCLEIDE software, internal conversion coefficients, and nuclide evaluations

  5. Educational Activity: A Preliminary Review and Some International Experiences

    Directory of Open Access Journals (Sweden)

    Salem Ali Al Qahtani

    2017-11-01

    Full Text Available This paper reviews the history of the educational activity which was entered through John Dewey’s Experimental School, founded in 1896, the first school to use the activity curriculum. It sheds the light on the stages that activity has gone through till today. The Islamic view and a number of quotes from a number of Islamic thinkers and educators also were reviewed. The importance of the activity, its basics, functions, types and classifications were also discussed. The research concluded with a number of international experiences which gave great importance to the activity in their curricula and educational plans. The most important recommendations are: 1 Offering advanced training programs for teachers on educational activity; 2 Adding educational activity as an independent material in educational colleges; 3 Expanding the scope of study for international experiences in educational activity; and 4 Making use of technology and employing it in the educational activity.

  6. Enzymatically active 2',5'-oligoadenylate synthetases are widely distributed among Metazoa, including protostome lineage.

    Science.gov (United States)

    Päri, Mailis; Kuusksalu, Anne; Lopp, Annika; Kjaer, Karina Hansen; Justesen, Just; Kelve, Merike

    2014-02-01

    2',5'-Oligoadenylate synthetases (OASs) belong to the nucleotidyl transferase family together with poly(A) polymerases, CCA-adding enzymes and the recently discovered cyclic-GMP-AMP synthase (cGAS). Mammalian OASs have been thoroughly characterized as components of the interferon-induced antiviral system. The OAS activity and the respective genes were also discovered in marine sponges where the interferon system is absent. In this study the recombinant OASs from several multicellular animals and their closest unicellular relative, a choanoflagellate, were expressed in a bacterial expression system and their enzymatic activities were examined. We demonstrated 2-5A synthesizing activities of OASs from the marine sponge Tedania ignis, a representative of the phylogenetically oldest metazoan phylum (Porifera), from an invertebrate of the protostome lineage, the mollusk Mytilus californianus (Mollusca), and from a vertebrate species, a cartilaginous fish Leucoraja erinacea (Chordata). However, the expressed proteins from an amphibian, the salamander Ambystoma mexicanum (Chordata), and from a protozoan, the marine choanoflagellate Monosiga brevicollis (Choanozoa), did not show 2-5A synthesizing activity. Differently from other studied OASs, OAS from the marine sponge T. ignis was able to catalyze the formation of oligomers having both 2',5'- and 3',5'-phosphodiester linkages. Our data suggest that OASs from sponges and evolutionarily higher animals have similar activation mechanisms which still include different affinities and possibly different structural requirements for the activating RNAs. Considering their 2'- and 3'-specificities, sponge OASs could represent a link between evolutionarily earlier nucleotidyl transferases and 2'-specific OASs from higher animals. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

  7. Participation in Armed Forces, National, and International Sports Activities

    Science.gov (United States)

    1987-03-09

    American Games , Olympic Games , and other authorized national and international sports competitions (to include qualifying and preparatory events) as long...concerning the participation of Armed Forces personnel in Armed Forces, national, and international sports competitions ; establishes a Senior Military Sports ...program is to ensure that the U.S. Armed Forces are appropriately represented in national and international sports competitions . 3. The purpose of this

  8. Acute cardiotoxicity with concurrent trastuzumab and radiotherapy including internal mammary chain nodes: A retrospective single-institution study

    International Nuclear Information System (INIS)

    Shaffer, Richard; Tyldesley, Scott; Rolles, Martin; Chia, Stephen; Mohamed, Islam

    2009-01-01

    Purpose: To examine the acute cardiotoxicity of internal mammary chain (IMC) irradiation with concurrent trastuzumab. Materials and Methods: Clinical and cardiac function data were collected on 59 patients with early breast cancer who were treated with adjuvant trastuzumab and chemotherapy with or without radiotherapy (often including IMC) at BC Cancer Agency in 2005. Results: Forty-four of fifty-nine patients received adjuvant radiotherapy (RT). Thirteen had left-sided IMC RT. For left-sided RT, IMC inclusion increased the mean percentage dose to 5% of the heart, but the mean doses to 50% and 90% of the heart were similar. Median baseline left ventricular ejection fraction (LVEF) was 62% and similar in all groups. Median absolute decrease in LVEF after RT was 4%, which was not significantly different according to side or inclusion of IMCs. Trastuzumab was stopped in 11 of 59 patients (18.6%) due to decrease in LVEF. After median follow up of 15 months, three patients developed clinical congestive heart failure, none of whom received left-sided IMC RT. Conclusions: There was no excess acute cardiotoxicity observed with the combination of left-sided IMC irradiation and concurrent trastuzumab

  9. Review of the IAEA nuclear fuel cycle and material section activities connected with nuclear fuel including WWER fuel

    International Nuclear Information System (INIS)

    Sokolov, F.

    2001-01-01

    Program activities on Nuclear Fuel Cycle and Materials cover the areas of: 1) raw materials (B.1.01); 2) fuel performance and technology (B.1.02); 3) pent fuel (B.1.03); 4) fuel cycle issues and information system (B.1.04); 5) support to technical cooperation activities (B.1.05). The IAEA activities in fuel performance and technology in 2001 include organization of the fuel experts meetings and completion of the Co-ordinate Research Projects (CRP). The special attention is given to the advanced post-irradiation examination techniques for water reactor fuel and fuel behavior under transients and LOCA conditions. An international research program on modeling of activity transfer in primary circuit of NPP is finalized in 2001. A new CRP on fuel modeling at extended burnup (FUMEX II) has planed to be carried out during the period 2002-2006. In the area of spent fuel management the implementation of burnup credit (BUC) in spent fuel management systems has motivated to be used in criticality safety applications, based on economic consideration. An overview of spent fuel storage policy accounting new fuel features as higher enrichment and final burnup, usage of MOX fuel and prolongation of the term of spent fuel storage is also given

  10. Should Cost-Effectiveness Analysis Include the Cost of Consumption Activities? AN Empirical Investigation.

    Science.gov (United States)

    Adarkwah, Charles Christian; Sadoghi, Amirhossein; Gandjour, Afschin

    2016-02-01

    There has been a debate on whether cost-effectiveness analysis should consider the cost of consumption and leisure time activities when using the quality-adjusted life year as a measure of health outcome under a societal perspective. The purpose of this study was to investigate whether the effects of ill health on consumptive activities are spontaneously considered in a health state valuation exercise and how much this matters. The survey enrolled patients with inflammatory bowel disease in Germany (n = 104). Patients were randomized to explicit and no explicit instruction for the consideration of consumption and leisure effects in a time trade-off (TTO) exercise. Explicit instruction to consider non-health-related utility in TTO exercises did not influence TTO scores. However, spontaneous consideration of non-health-related utility in patients without explicit instruction (60% of respondents) led to significantly lower TTO scores. Results suggest an inclusion of consumption costs in the numerator of the cost-effectiveness ratio, at least for those respondents who spontaneously consider non-health-related utility from treatment. Results also suggest that exercises eliciting health valuations from the general public may include a description of the impact of disease on consumptive activities. Copyright © 2015 John Wiley & Sons, Ltd.

  11. Applications of neutron activation analysis in determination of natural and man-made radionuclides, including PA-231

    Science.gov (United States)

    Byrne, A. R.; Benedik, L.

    1999-01-01

    Neutron activation analysis (NAA), being essentially an isotopic and not an elemental method of analysis, is capable of determining a number of important radionuclides of radioecological interest by transformation into another, more easily quantifiable radionuclide. The nuclear characteristics which favour this technique may be summarized in an advantage factor relative to radiometric analysis of the original radioanalyte. Well known or hardly known examples include235U,238U,232Th,230Th,129I,99Tc,237Np and231Pa; a number of these are discussed and illustrated in analysis of real samples of environmental and biological origin. In particular, determination of231Pa by RNAA was performed using both postirradiation and preseparation methods. Application of INAA to enable the use of238U and232Th as endogenous (internal) radiotracers in alpha spectrometric analyses of uranium and thorium radioisotopes in radioecological studies is described, also allowing independent data sets to be obtained for quality control.

  12. International conference activation analysis and its applications (ICAAA): abstracts

    International Nuclear Information System (INIS)

    1990-01-01

    International conference on the Activation Analysis and its Applications was hold in Beijing of China on October 15-19, 1990. It was organized and co-sponsored by Division of Activation Analysis and Radioanalysis, National Natural Science Foundation of China and China Nuclear Society, etc.. 159 pieces of Articles in the field were received in the conference, from many countries

  13. Gulf of Mexico rig activity up, international lags

    International Nuclear Information System (INIS)

    Rappold, K.

    1994-01-01

    Demand for jack up and semisubmersible rigs has improved in the Gulf of Mexico following a decline in activity earlier this year. International drilling activity, however, has shown slight declines in several regions. Relatively firm natural gas prices have helped buoy rig activity in North America. Rig day rates have not followed suit, mainly because of the influx of rigs from weaker international markets. Day rates in the US may not increase until international activity picks up and the world-wide drilling market tightens. Oil prices have hit almost $20/bbl, mainly because of the recent oil worker' strike in Nigeria and good demand. Natural gas prices in the US have hovered around $2.00/MMBTU, and many industry analysts expect gas prices to remain strong over the next few years. This paper gives data on drilling rig counts and crude oil and gas prices in the Gulf of Mexico and onshore

  14. International inspection activity impacts upon DOE safeguards requirements

    International Nuclear Information System (INIS)

    Zack, N.R.

    1995-01-01

    The US has placed certain special nuclear materials declared excess to their strategic needs under international safeguards through the International Atomic Energy Agency (IAEA). This Presidential initiative has obligated materials at several Department of Energy (DOE) facilities for these safeguards activities to demonstrate the willingness of the US to ban production or use of nuclear materials outside of international safeguards. However, IAEA inspection activities generally tend to be intrusive in nature and are not consistent with several domestic safeguards procedures implemented to reduce worker radiation exposures and increase the cost-effectiveness and efficiency of accounting for and storing of special nuclear materials. To help identify and provide workable solutions to these concerns, the Office of Safeguards and Security has conducted a program to determine possible changes to the DOE safeguards and security requirements designed to help facilities under international safeguards inspections more easily comply with domestic safeguards goals during international inspection activities. This paper will discuss the impact of international inspection activities on facility safeguards operations and departmental safeguards procedures and policies

  15. Characteristics of an β-N-Acetylhexosaminidase from Bacillus sp. CH11, Including its Transglycosylation Activity.

    Science.gov (United States)

    Kurakake, Masahiro; Amai, Yukari; Konishi, Mizuki; Ikehira, Kaho

    2018-04-06

    β-N-Acetylhexosaminidase was identified from Bacillus sp. CH11 and found to have relatively high transferring activity. In this study, its enzymatic properties and transglycosylation activity including its acceptor specificity were investigated. Its molecular weight was estimated to be 90 kDa by SDS-PAGE and its optimal pH was approximately 7 with good stability from pH 6 to 8. Its optimal temperature was 40 °C, and its activity was stable at temperatures of up to 40 °C. To analyze its acceptor specificity for transglycosylation, N, N'-diacetylchitobiose was used as a donor substrate and alcohols, sugar alcohols, sugars and polyphenols were used as acceptors. Dialcohols, which have 2 hydroxyl groups on the outside of the carbon chains, were good acceptors. The molecular size of the acceptor did not influence the transglycosylation up to at least 1,5-pentanediol (carbon number: C5). Glycerin (C3), erythritol (C4), and xylitol (C5), all small molecular weight sugar alcohols, had high acceptor specificity. Transglycosylation to mono- and disaccharides and polyphenols was not observed except for L-fucose. For the β-N-acetylhexosaminidase-catalyzed transglycosylation of chitin oligosaccharides and xylitol, the transfer product was identified as 1-O-β-D-N-acetylglucosaminyl xylitol. The optimal ratio of xylitol was 24% to 2% N, N'-diacetylchitobiose and 226 mg per 1 g N, N'-diacetylchitobiose was produced. CH11 β-N-acetylhexosaminidase efficiently produced 1-O-β-D-N-acetylglucosaminyl xylitol via transglycosylation. The new transfer products including 1-O-β-D-N-acetylglucosaminyl xylitol are attractive compounds for their potential physiological functions. 1-O-β-D-N-Acetylglucosaminyl xylitol was produced effectively from chitin-oligosaccharides and xylitol by β-N-acetylhexosaminidase from Bacillus sp. CH11. This enzyme may be useful for the development of food materials for health-related applications such as oligosaccharides with intestinal functions and

  16. Plasma Hazards and Acceptance for International Space Station Extravehicular Activities

    Science.gov (United States)

    Patton, Thomas

    2010-09-01

    Extravehicular activity(EVA) is accepted by NASA and other space faring agencies as a necessary risk in order to build and maintain a safe and efficient laboratory in space. EVAs are used for standard construction and as contingency operations to repair critical equipment for vehicle sustainability and safety of the entire crew in the habitable volume. There are many hazards that are assessed for even the most mundane EVA for astronauts, and the vast majority of these are adequately controlled per the rules of the International Space Station Program. The need for EVA repair and construction has driven acceptance of a possible catastrophic hazard to the EVA crewmember which cannot currently be controlled adequately. That hazard is electrical shock from the very environment in which they work. This paper describes the environment, causes and contributors to the shock of EVA crewmembers attributed to the ionospheric plasma environment in low Earth orbit. It will detail the hazard history, and acceptance process for the risk associated with these hazards that give assurance to a safe EVA. In addition to the hazard acceptance process this paper will explore other factors that go into the decision to accept a risk including criticality of task, hardware design and capability, and the probability of hazard occurrence. Also included will be the required interaction between organizations at NASA(EVA Office, Environments, Engineering, Mission Operations, Safety) in order to build and eventually gain adequate acceptance rationale for a hazard of this kind. During the course of the discussion, all current methods of mitigating the hazard will be identified. This paper will capture the history of the plasma hazard analysis and processes used by the International Space Station Program to formally assess and qualify the risk. The paper will discuss steps that have been taken to identify and perform required analysis of the floating potential shock hazard from the ISS environment

  17. GENERAL ASPECTS REGARDING THE MANAGEMENT ACTIVITY IN INTERNATIONAL BUSINESS

    Directory of Open Access Journals (Sweden)

    Mihaela Loredana LĂPĂDUŞI

    2010-09-01

    Full Text Available The strategy of penetrating and developing the external markets is an important objective of the international enterprises management. This involves a specific analysis of the business environment for illustrating the opportunities of business and risks and the business potential of a particular enterprise in order to establish the internalisation objectives and types. The international management is individualised by the environment where the enterprises develop their economical activity, supposing that the world market of international business involves the access to new markets and the enterprises must adapt to the specific needs and opportunities.

  18. Fluorogenic MMP activity assay for plasma including MMPs complexed to α2-macroglobulin

    NARCIS (Netherlands)

    Beekman, B.; Drijfhout, J.W.; Ronday, H.K.; TeKoppele, J.M.

    1999-01-01

    Elevated MMP activities are implicated in tissue degradation in, e.g., arthritis and cancer. The present study was designed to measure MMP enzyme activity in plasma. Free active MMP is unlikely to be present in plasma: upon entering the circulation, active MMP is expected to be captured by the

  19. A Dosimetric Comparison of Breast Radiotherapy Techniques to Treat Locoregional Lymph Nodes Including the Internal Mammary Chain.

    Science.gov (United States)

    Ranger, A; Dunlop, A; Hutchinson, K; Convery, H; Maclennan, M K; Chantler, H; Twyman, N; Rose, C; McQuaid, D; Amos, R A; Griffin, C; deSouza, N M; Donovan, E; Harris, E; Coles, C E; Kirby, A

    2018-06-01

    Radiotherapy target volumes in early breast cancer treatment increasingly include the internal mammary chain (IMC). In order to maximise survival benefits of IMC radiotherapy, doses to the heart and lung should be minimised. This dosimetry study compared the ability of three-dimensional conformal radiotherapy, arc therapy and proton beam therapy (PBT) techniques with and without breath-hold to achieve target volume constraints while minimising dose to organs at risk (OARs). In 14 patients' datasets, seven IMC radiotherapy techniques were compared: wide tangent (WT) three-dimensional conformal radiotherapy, volumetric-modulated arc therapy (VMAT) and PBT, each in voluntary deep inspiratory breath-hold (vDIBH) and free breathing (FB), and tomotherapy in FB only. Target volume coverage and OAR doses were measured for each technique. These were compared using a one-way ANOVA with all pairwise comparisons tested using Bonferroni's multiple comparisons test, with adjusted P-values ≤ 0.05 indicating statistical significance. One hundred per cent of WT(vDIBH), 43% of WT(FB), 100% of VMAT(vDIBH), 86% of VMAT(FB), 100% of tomotherapy FB and 100% of PBT plans in vDIBH and FB passed all mandatory constraints. However, coverage of the IMC with 90% of the prescribed dose was significantly better than all other techniques using VMAT(vDIBH), PBT(vDIBH) and PBT(FB) (mean IMC coverage ± 1 standard deviation = 96.0% ± 4.3, 99.8% ± 0.3 and 99.0% ± 0.2, respectively). The mean heart dose was significantly reduced in vDIBH compared with FB for both the WT (P FB). Simple WT radiotherapy delivered in vDIBH achieves satisfactory coverage of the IMC while meeting heart and lung dose constraints. However, where higher isodose coverage is required, VMAT(vDIBH) is the optimal photon technique. The lowest OAR doses are achieved by PBT, in which the use of vDIBH does not improve dose statistics. Crown Copyright © 2018. Published by Elsevier Ltd. All rights reserved.

  20. Results submitted to Bureau International des Poids et Mesures (BIPM) for international comparison on 134Cs activity

    International Nuclear Information System (INIS)

    Gibson, F.H.; Smith, L.V.; Rutledge, A.R.; Merritt, J.S.

    1979-02-01

    This report describes the equipment used and the results obtained by the Radioisotope Standardization Group in its participation in the international comparison of activity measurements of a 134 Cs solution that was sponsored by Bureau International des Poids et Mesures (BIPM). The 4π(PC)-γ coincidence method was used with the γ-channel gate set narrowly around photopeaks of approximately 800 keV. The results are compared with those from three other γ-channel gates. An assessment of known and suspected sources of uncertainty is included. (author)

  1. The International Association for Promoting Geoethics: Mission, Organization, and Activities

    Science.gov (United States)

    Kieffer, S. W.; Peppoloni, S.; Di Capua, G.

    2017-12-01

    The International Association for Promoting Geoethics (IAPG) was founded in 2012, during the 34th IGC in Brisbane (Australia), to provide a multidisciplinary platform for widening the discussion and creating awareness about principles and problems of ethics as applied to the geosciences. It is a scientific, non-governmental, non-political, non-profit, non-party institution, headquartered at the Italian Institute of Geophysics and Volcanology in Rome, Italy. IAPG focuses on behaviors and practices where human activities interact with the Earth system, and deals with the ethical, social and cultural implications of geoscience knowledge, education, research, practice and communication. Its goal is to enhance awareness of the social role and responsibility of geoscientists in conducting their activities such as geoeducation, sustainability, and risk prevention. IAPG is a legally recognized non-profit association with members in 115 countries on 5 continents, and currently has 26 national sections. As of the date of this abstract, IAPG has been involved with approximately 70 international meetings (scientific conferences, symposia, seminars, workshops, expositions, etc.). Other activities range from exchanging information with newsletters, blogs, social networks and publications; promoting the creation of working groups and encouraging the participation of geoscientists within universities and professional associations for the development of geoethics themes; and cooperating with national and international organizations whose aims are complementary, e.g., International Union of Geological Sciences (IUGS), American Geosciences Institute (AGI), Geological Society of America (GSA), Geological Society of London (GSL), Geoscience Information in Africa - Network (GIRAF), American Geophysical Union (AGU), International Association for Engineering Geology and the Environment (IAEG), International Association of Hydrogeologists (IAH), Association of Environmental & Engineering

  2. Measuring Outcomes in Adult Weight Loss Studies That Include Diet and Physical Activity: A Systematic Review

    Directory of Open Access Journals (Sweden)

    Rachel A. Millstein

    2014-01-01

    Full Text Available Background. Measuring success of obesity interventions is critical. Several methods measure weight loss outcomes but there is no consensus on best practices. This systematic review evaluates relevant outcomes (weight loss, BMI, % body fat, and fat mass to determine which might be the best indicator(s of success. Methods. Eligible articles described adult weight loss interventions that included diet and physical activity and a measure of weight or BMI change and body composition change. Results. 28 full-text articles met inclusion criteria. Subjects, settings, intervention lengths, and intensities varied. All studies measured body weight (−2.9 to −17.3 kg, 9 studies measured BMI (−1.1 to −5.1 kg/m2, 20 studies measured % body fat (−0.7 to −10.2%, and 22 studies measured fat mass (−0.9 to −14.9 kg. All studies found agreement between weight or BMI and body fat mass or body fat % decreases, though there were discrepancies in degree of significance between measures. Conclusions. Nearly all weight or BMI and body composition measures agreed. Since body fat is the most metabolically harmful tissue type, it may be a more meaningful measure of health change. Future studies should consider primarily measuring % body fat, rather than or in addition to weight or BMI.

  3. Performance of cement solidification with barium for high activity liquid waste including sulphate

    International Nuclear Information System (INIS)

    Waki, Toshikazu; Yamada, Motoyuki; Horikawa, Yoshihiko; Kaneko, Masaaki; Saso, Michitaka; Haruguchi, Yoshiko; Yamashita, Yu; Sakai, Hitoshi

    2009-01-01

    The target liquid waste to be solidified is generated from PWR primary loop spent resin treatment with sulphate acid, so, its main constituent is sodium sulphate and the activity of this liquid is relatively high. Waste form of this liquid waste is considered to be a candidate for the subsurface disposal. The disposed waste including sulphate is anticipated to rise a concentration of sulphate ion in the ground water around the disposal facility and it may cause degradation of materials such as cement and bentonite layer and comprise the disposal facility. There could be two approaches to avoid this problem, the strong design of the disposal facility and the minimization of sulphaste ion migration from the solidified waste. In this study, the latter approach was examined. In order to keep the low concentration of sulphate ion in the ground water, it is effective to make barium sulphate by adding barium compound into the liquid waste in solidification. However, adding equivalent amount of barium compound with sulphate ion causes difficulty of mixing, because production of barium sulphate causes high viscosity. In this study, mixing condition after and before adding cement into the liquid waste was estimated. The mixing condition was set with consideration to keep anion concentration low in the ground water and of mixing easily enough in practical operation. Long term leaching behavior of the simulated solidified waste was also analyzed by PHREEQC. And the concentration of the constitution affected to the disposal facility was estimated be low enough in the ground water. (author)

  4. Evaluation of the Supraglottic and Subglottic Activities Including Acoustic Assessment of the Opera-Chant Singers.

    Science.gov (United States)

    Petekkaya, Emine; Yücel, Ahmet Hilmi; Sürmelioğlu, Özgür

    2017-12-28

    Opera and chant singers learn to effectively use aerodynamic components by breathing exercises during their education. Aerodynamic components, including subglottic air pressure and airflow, deteriorate in voice disorders. This study aimed to evaluate the changes in aerodynamic parameters and supraglottic structures of men and women with different vocal registers who are in an opera and chant education program. Vocal acoustic characteristics, aerodynamic components, and supraglottic structures were evaluated in 40 opera and chant art branch students. The majority of female students were sopranos, and the male students were baritone or tenor vocalists. The acoustic analyses revealed that the mean fundamental frequency was 152.33 Hz in the males and 218.77 Hz in the females. The estimated mean subglottal pressures were similar in females (14.99 cmH 2 O) and in males (14.48 cmH 2 O). Estimated mean airflow rates were also similar in both groups. The supraglottic structure compression analyses revealed partial anterior-posterior compressions in 2 tenors and 2 sopranos, and false vocal fold compression in 2 sopranos. Opera music is sung in high-pitched sounds. Attempts to sing high-pitched notes and frequently using register transitions overstrain the vocal structures. This intense muscular effort eventually traumatizes the vocal structures and causes supraglottic activity. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  5. Comparison of normal tissue dose with three-dimensional conformal techniques for breast cancer irradiation including the internal mammary nodes

    NARCIS (Netherlands)

    van der Laan, Hans Paul; Dolsma, Willemtje; van t Veld, Aart; Bijl, HP; Langendijk, JA

    2005-01-01

    PURPOSE: To compare the Para Mixed technique for irradiation of the internal mammary nodes (IMN) with three commonly used strategies, by analyzing the dose to the heart and other organs at risk. METHODS AND MATERIALS: Four different three-dimensional conformal dose plans were created for 30 breast

  6. Macroenvironmental factors including GDP per capita and physical activity in Europe

    NARCIS (Netherlands)

    Cameron, Adrian J.; van Stralen, Maartje M.; Kunst, Anton E.; te Velde, Saskia J.; van Lenthe, Frank J.; Salmon, Jo; Brug, Johannes

    2013-01-01

    Socioeconomic inequalities in physical activity at the individual level are well reported. Whether inequalities in economic development and other macroenvironmental variables between countries are also related to physical activity at the country level is comparatively unstudied. We examined the

  7. Macroenvironmental Factors Including GDP per Capita and Physical Activity in Europe

    NARCIS (Netherlands)

    Cameron, A.J.; van Stralen, M.M.; Kunst, A.E.; te Velde, S.J.; Lenthe, F.J.; Salmon, J.; Brug, J.

    2013-01-01

    Purpose: Socioeconomic inequalities in physical activity at the individual level are well reported. Whether inequalities in economic development and other macroenvironmental variables between countries are also related to physical activity at the country level is comparatively unstudied. Methods: We

  8. A project in support of international nuclear cooperation activities

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jeongkong; Kim, Myungro; Choi, Pyunghoon; Kim, Kyungpyo; Jung, Sunghyon; Park, Jiyeon; Eom, Jaesik; Kim, Wangkeun; Chung, Byungsun

    2011-12-15

    This study contains the work undertaken to promote multilateral cooperation within the framework of international nuclear related organizations and regional cooperative agreements and the relevant forums, to enhance bilateral cooperation with foreign nuclear related research institutes as well as to promote cooperation through the exchange of foreign scientists. As for multilateral cooperation, activities for promoting cooperation within the IAEA and regional cooperative frameworks are introduced. Regarding bilateral cooperation, activities for concluding arrangements and MOUs with foreign research institutes and for participation in joint nuclear coordinating committee meetings between Korea and other countries are presented. For promoting personnel exchanges, activities for inviting and utilizing foreign scientists and mutual discussions with foreign experts, who have visited KAERI, are also described. Continuous efforts to contributing towards the international community through utilizing Korea's experience gained in the process of technical self-reliance and development of human resources are needed. Also efforts to establish the foundation of international cooperation and to make inroad into overseas nuclear markets for export of our nuclear technologies should be made. Meanwhile in the bilateral cooperation, we need to beef up cooperation with U. S. A. and Canada through the joint committee for the joint export to third countries. It is expected that this study would be utilized as a basic material for the international cooperation of nuclear energy, especially for the KAERI's international cooperation in an effective way.

  9. Overview of International Thermonuclear Experimental Reactor (ITER) engineering design activities*

    Science.gov (United States)

    Shimomura, Y.

    1994-05-01

    The International Thermonuclear Experimental Reactor (ITER) [International Thermonuclear Experimental Reactor (ITER) (International Atomic Energy Agency, Vienna, 1988), ITER Documentation Series, No. 1] project is a multiphased project, presently proceeding under the auspices of the International Atomic Energy Agency according to the terms of a four-party agreement among the European Atomic Energy Community (EC), the Government of Japan (JA), the Government of the Russian Federation (RF), and the Government of the United States (US), ``the Parties.'' The ITER project is based on the tokamak, a Russian invention, and has since been brought to a high level of development in all major fusion programs in the world. The objective of ITER is to demonstrate the scientific and technological feasibility of fusion energy for peaceful purposes. The ITER design is being developed, with support from the Parties' four Home Teams and is in progress by the Joint Central Team. An overview of ITER Design activities is presented.

  10. Some activities at CEA related to behaviour of core internals

    International Nuclear Information System (INIS)

    Petrequin, P.

    1998-01-01

    Eighteen transparencies where presented, elaborating some activities at CEA related to behaviour of core internals. After some introduction, ten of the transparencies are essentially a copy of the table of contents of the AMES report no. 11 (report no: EUR 17694 EN). The remaining 6 foils concerned themselves with irradiation experiments in test reactors, namely the IDAHO, CASIMIR and ALEXANDRA experiments

  11. Does limited virucidal activity of biocides include duck hepatitis B virucidal action?

    Directory of Open Access Journals (Sweden)

    Sauerbrei Andreas

    2012-10-01

    Full Text Available Abstract Background There is agreement that the infectivity assay with the duck hepatitis B virus (DHBV is a suitable surrogate test to validate disinfectants for hepatitis B virucidal activity. However, since this test is not widely used, information is necessary whether disinfectants with limited virucidal activity also inactivate DHBV. In general, disinfectants with limited virucidal activity are used for skin and sensitive surfaces while agents with full activity are more aggressive. The present study compares the activity of five different biocides against DHBV and the classical test virus for limited virucidal activity, the vaccinia virus strain Lister Elstree (VACV or the modified vaccinia Ankara strain (MVA. Methods Virucidal assay was performed as suspension test according to the German DVV/RKI guideline. Duck hepatitis B virus obtained from congenitally infected Peking ducks was propagated in primary duck embryonic hepatocytes and was detected by indirect immunofluorescent antigen staining. Results The DHBV was inactivated by the use of 40% ethanol within 1-min and 30% isopropanol within 2-min exposure. In comparison, 40% ethanol within 2-min and 40% isopropanol within 1-min exposure were effective against VACV/MVA. These alcohols only have limited virucidal activity, while the following agents have full activity. 0.01% peracetic acid inactivated DHBV within 2 min and a concentration of 0.005% had virucidal efficacy against VACV/MVA within 1 min. After 2-min exposure, 0.05% glutardialdehyde showed a comparable activity against DHBV and VACV/MVA. This is also the case for 0.7% formaldehyde after a contact time of 30 min. Conclusions Duck hepatitis B virus is at least as sensitive to limited virucidal activity as VACV/MVA. Peracetic acid is less effective against DHBV, while the alcohols are less effective against VACV/MVA. It can be expected that in absence of more direct tests the results may be extrapolated to HBV.

  12. Organization of the ITER Co-ordinated Technical Activities International Team

    International Nuclear Information System (INIS)

    2001-01-01

    At its meeting in Toronto on 7 November 2001, the ITER Co-ordinated Technical Activities (CTA) project board took note of the organizational arrangements for the CTA International Team at the Garching and Naka joint work sites. The organization chart of the team remains almost unchanged from that of the ITER Engineering Design Activities (EDA). However, there is no special division responsible for plasma and field control. Activities in plasma control will be taken over by the Physics Unit. This newsletter also includes the ITER CTA International Team structure

  13. Status of UFD Campaign International Activities in Disposal Research

    Energy Technology Data Exchange (ETDEWEB)

    Birkholzer, Jens [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2012-09-01

    While the United States research program for geologic disposal of high-level radioactive waste over the past decades focused solely on an open tunnel emplacement in unsaturated densely fractured tuff, several international organizations have made significant progress in the characterization and performance evaluation of other disposal design options and host rock characteristics, most of which were very different from those studied in the U.S. As a result, areas of direct collaboration between the U.S. Department of Energy’s (DOE) and international geologic disposal programs were quite limited during that time. Recently, the decision by DOE to no longer pursue the geologic disposal of high-level radioactive waste and spent fuel at the Yucca Mountain site has shifted the nation’s focus to disposal design options and geologic environments similar to those being investigated by other nations. DOE started to recognize that close international collaboration is a beneficial and costeffective strategy for advancing disposal science and, in FY12, embarked on a comprehensive effort to identify international collaboration opportunities, to interact with international organizations and advance promising collaborations, and to plan/develop specific R&D activities in cooperation with international partners. This report describes the active collaboration opportunities available to U.S. researchers as a result of this effort, and presents specific cooperative research activities that have been recently initiated within DOE’s disposal research program. The focus in this report is on those opportunities that provide access to field data (and respective interpretation/modeling), and/or may allow participation in ongoing and planned field experiments.

  14. Managing nuclear knowledge: IAEA activities and international coordination. Asian Network for Education in Nuclear Technology (ANENT)

    International Nuclear Information System (INIS)

    2007-07-01

    This CD-ROM is attached to the booklet 'Managing nuclear knowledge: IAEA activities and international coordination. Asian Network for Education in Nuclear Technology (ANENT)'. It contains the background material with regard to ANENT in full text, including policy level papers, reports, presentation material made by Member States, and meeting summaries during the period 2002-2005. Further information on the current ANENT activities and related IAEA activities is available at 'http://anent-iaea.org' and 'http://iaea.org/inisnkm'

  15. Estimations of internal dosimetry: practical calculations of incorporated activity

    International Nuclear Information System (INIS)

    Cortes C, A.

    2003-01-01

    The National Commission of Nuclear Security and Safeguards (CNSNS) carries out periodically measurements of corporal activity to Occupationally Exposed Personnel (POE) to determine that the received doses are in according to that settled down in the General Regulation of Radiological Security. In this work the results of the incorporated activity estimates starting from the results of the measurements that were carried out in the one CNSNS laboratory are presented, with which it should be determine lastly the internal dose. Its were used different methodologies to estimate the incorporated activity: estimate with isolated data, estimate with global data and method of the best estimate, demonstrating this last to be the more appropriate to determine the internal dose. (Author)

  16. International Centre for Theoretical Physics, Trieste. Scientific activities in 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-10-01

    This publication gives a comprehensive overview of the scientific activities during 1994 of the International Centre for Theoretical Physics, Trieste. In particular, it gives (i) a summary of these activities accompanied by statistical data (comparison with 1993, participation by geographical area, breakdown by field of activity, activities held at and outside the ICTP, and participation by activity); (ii) an overview of the scientific programme (fundamental physics, condensed matter physics, mathematics, physics and energy, physics and the environment, physics of the living state, applied physics, diploma courses, and other research) while listing long-term visitors, networks of associate members and federal institutes, training and research at Italian laboratories, external activities, science, the high technology and development programme, the books and equipment programme, award; (iii) a list of publications, and (iv) a list of scientific support services.

  17. International Centre for Theoretical Physics, Trieste. Scientific activities in 1994

    International Nuclear Information System (INIS)

    1995-10-01

    This publication gives a comprehensive overview of the scientific activities during 1994 of the International Centre for Theoretical Physics, Trieste. In particular, it gives (i) a summary of these activities accompanied by statistical data (comparison with 1993, participation by geographical area, breakdown by field of activity, activities held at and outside the ICTP, and participation by activity); (ii) an overview of the scientific programme (fundamental physics, condensed matter physics, mathematics, physics and energy, physics and the environment, physics of the living state, applied physics, diploma courses, and other research) while listing long-term visitors, networks of associate members and federal institutes, training and research at Italian laboratories, external activities, science, the high technology and development programme, the books and equipment programme, award; (iii) a list of publications, and (iv) a list of scientific support services

  18. Generalized internal model robust control for active front steering intervention

    Science.gov (United States)

    Wu, Jian; Zhao, Youqun; Ji, Xuewu; Liu, Yahui; Zhang, Lipeng

    2015-03-01

    Because of the tire nonlinearity and vehicle's parameters' uncertainties, robust control methods based on the worst cases, such as H ∞, µ synthesis, have been widely used in active front steering control, however, in order to guarantee the stability of active front steering system (AFS) controller, the robust control is at the cost of performance so that the robust controller is a little conservative and has low performance for AFS control. In this paper, a generalized internal model robust control (GIMC) that can overcome the contradiction between performance and stability is used in the AFS control. In GIMC, the Youla parameterization is used in an improved way. And GIMC controller includes two sections: a high performance controller designed for the nominal vehicle model and a robust controller compensating the vehicle parameters' uncertainties and some external disturbances. Simulations of double lane change (DLC) maneuver and that of braking on split- µ road are conducted to compare the performance and stability of the GIMC control, the nominal performance PID controller and the H ∞ controller. Simulation results show that the high nominal performance PID controller will be unstable under some extreme situations because of large vehicle's parameters variations, H ∞ controller is conservative so that the performance is a little low, and only the GIMC controller overcomes the contradiction between performance and robustness, which can both ensure the stability of the AFS controller and guarantee the high performance of the AFS controller. Therefore, the GIMC method proposed for AFS can overcome some disadvantages of control methods used by current AFS system, that is, can solve the instability of PID or LQP control methods and the low performance of the standard H ∞ controller.

  19. The environment protection at the 21. century: radiological protection of the biosphere including man. Declaration of International union of radioecology

    International Nuclear Information System (INIS)

    Brechignac, F.; Polikarpov, G.; Oughton, D.H.; Hunter, G.; Alexakhin, R.; Zhu, Y.G.; Hilton, J.; Strand, P.

    2003-01-01

    The International union of radioecology has been created in 1970 as an international scientific organisation to develop, inform and advise on every aspect in relation with radioactivity in environment. It advises to fill the gaps of knowledge in order to develop strong scientific bases on which found the environmental protection. Seven points of knowledge are to improve: the understanding of transfer, bio accumulating and metabolism of radionuclides in ecosystems (specially the non human food chains), understanding of low dose radiation effects on fauna, flora in chronic exposure on several generations, identification of criteria and targets of effects to allow comparisons in term of impact, effects coming from several pollutions, radioactive or non radioactive ones, extrapolation between the biological organisation levels, analysis of simultaneous effects for man and other living organisms, harmonization of a radiation protection system and a protection system against chemical toxicity, development of quantities and units allowing to qualify the noxious effects of radiations and chemical pollutants on living beings. (N.C.)

  20. Validity of the International Physical Activity Questionnaire in the Arctic

    DEFF Research Database (Denmark)

    Dahl-Petersen, Inger Katrine; Hansen, Andreas Wolf; Bjerregaard, Peter

    2013-01-01

    PURPOSE: Information about physical activity (PA) in Greenland is limited, partly due to a lack of validated instruments in countries with non-western living conditions. We modified the long form of the International Physical Activity Questionnaire (IPAQ-L) to arctic living conditions. The aim......=1508). Physical activity energy expenditure (PAEE) and time spent sedentary and on PA at moderate and vigorous intensity were derived from IPAQ-L and ACC+HR. Estimates were compared using Bland-Altman agreement analysis and Spearman correlations stratified by sex, place of residence (capital, towns...

  1. Etude Climat no. 34 'Including international aviation in the EU ETS: a first step towards a global scheme'

    International Nuclear Information System (INIS)

    Alberola, Emilie; Solier, Boris

    2012-01-01

    Among the publications of CDC Climat Research, 'Climate Reports' offer in-depth analyses on a given subject. This issue addresses the following points: CO 2 emissions from international aviation, which accounted for 2% of global emissions in 2009, are not currently capped by any international agreement. The inclusion of the aviation sector in the European Union Emissions Trading Scheme (EU ETS) from January 1 2012 onwards represents a first step towards the implementation of emission reduction regulations based on an emissions trading scheme After the gradual extension of the scope of the EU ETS to new countries since 2005, the European Commission is now assimilating around 5,400 airlines that operate in Europe, two-thirds of which are non-European, into the EU ETS to join the energy generation and manufacturing industries. This European Union's decision assigns quantified CO 2 emission reduction targets to airlines: a 3% reduction in 2012 compared with average CO 2 emissions for the sector between 2004 and 2006, then a 5% reduction between 2013 and 2020. In the short term, the inclusion of the aviation sector in the EU ETS should have an impact on the scheme. Indeed, the aviation sector is expected to represent a new source of demand for allowances. Based on the assumption of an average 2.5% increase in annual emissions between 2012 and 2014, and then of an increase of 2% over the period between 2015 and 2020, airlines would create a shortfall of 382 MtCO 2 between 2012 and 2020. The limited use of Kyoto credits to help them comply offers a maximum import potential of almost 65 MtCO 2 between 2012 and 2020. This inclusion is a test of the EU's proactive policy, which involves encouraging other countries to define their own climate policy, without breaching international law,. The potential exemption of airline operators from emitter countries that introduce equivalent regulations would be a success for the European policy. For the time being, the reaction of some

  2. Intracellular activity of clinical concentrations of phenothiazines including thioridiazine against phagocytosed Staphylococcus aureus.

    Science.gov (United States)

    Ordway, Diane; Viveiros, Miguel; Leandro, Clara; Arroz, Maria Jorge; Amaral, Leonard

    2002-07-01

    The effect of thioridazine (TZ) was studied on the killing activity of human peripheral blood monocyte derived macrophages (HPBMDM) and of human macrophage cell line THP-1 at extracellular concentrations below those achievable clinically. These macrophages have nominal killing activity against bacteria and therefore, would not influence any activity that the compounds may have against intracellular localised Staphylococcus aureus. The results indicated that whereas TZ has an in vitro minimum inhibitory concentration (MIC) against the strains of S. aureus of 18, 0.1 mg/l of TZ in the medium completely inhibits the growth of S. aureus that has been phagocytosed by macrophages. The latter concentration was non-toxic to macrophages, did not cause cellular expression of activation marker CD69 nor induction of CD3+ T cell production of IFN-gamma, but blocked cellular proliferation and down-regulated the production of T cell-derived cytokines (IFN-gamma, IL-5). These results suggest that TZ induces intracellular bactericidal activities independent of the capacity to generate Type 1 responses against S. aureus.

  3. Parameterization of cloud droplet formation for global and regional models: including adsorption activation from insoluble CCN

    Directory of Open Access Journals (Sweden)

    P. Kumar

    2009-04-01

    Full Text Available Dust and black carbon aerosol have long been known to exert potentially important and diverse impacts on cloud droplet formation. Most studies to date focus on the soluble fraction of these particles, and overlook interactions of the insoluble fraction with water vapor (even if known to be hydrophilic. To address this gap, we developed a new parameterization that considers cloud droplet formation within an ascending air parcel containing insoluble (but wettable particles externally mixed with aerosol containing an appreciable soluble fraction. Activation of particles with a soluble fraction is described through well-established Köhler theory, while the activation of hydrophilic insoluble particles is treated by "adsorption-activation" theory. In the latter, water vapor is adsorbed onto insoluble particles, the activity of which is described by a multilayer Frenkel-Halsey-Hill (FHH adsorption isotherm modified to account for particle curvature. We further develop FHH activation theory to i find combinations of the adsorption parameters AFHH, BFHH which yield atmospherically-relevant behavior, and, ii express activation properties (critical supersaturation that follow a simple power law with respect to dry particle diameter.

    The new parameterization is tested by comparing the parameterized cloud droplet number concentration against predictions with a detailed numerical cloud model, considering a wide range of particle populations, cloud updraft conditions, water vapor condensation coefficient and FHH adsorption isotherm characteristics. The agreement between parameterization and parcel model is excellent, with an average error of 10% and R2~0.98. A preliminary sensitivity study suggests that the sublinear response of droplet number to Köhler particle concentration is not as strong for FHH particles.

  4. Measures for the capitalization of internal control activity performed on the entity's financial and accounting activities

    OpenAIRE

    Doina Maria Tilea; Dragos Zaharia

    2013-01-01

    In the organization of internal control flexibility is required because if a rule is too rigid or no longer current it can leads to inefficiency. Current organizational complexity involving the private sector to organize a system of internal control to fold on this, which can cover a territory so expanded and a wide variety of activities. Thus, the Company's internal controls is exercised at the level of each structure and because of the importance and implications of the financial ones are h...

  5. Using assistive technology adaptations to include students with learning disabilities in cooperative learning activities.

    Science.gov (United States)

    Bryant, D P; Bryant, B R

    1998-01-01

    Cooperative learning (CL) is a common instructional arrangement that is used by classroom teachers to foster academic achievement and social acceptance of students with and without learning disabilities. Cooperative learning is appealing to classroom teachers because it can provide an opportunity for more instruction and feedback by peers than can be provided by teachers to individual students who require extra assistance. Recent studies suggest that students with LD may need adaptations during cooperative learning activities. The use of assistive technology adaptations may be necessary to help some students with LD compensate for their specific learning difficulties so that they can engage more readily in cooperative learning activities. A process for integrating technology adaptations into cooperative learning activities is discussed in terms of three components: selecting adaptations, monitoring the use of the adaptations during cooperative learning activities, and evaluating the adaptations' effectiveness. The article concludes with comments regarding barriers to and support systems for technology integration, technology and effective instructional practices, and the need to consider technology adaptations for students who have learning disabilities.

  6. Observing a fictitious stressful event: haematological changes, including circulating leukocyte activation.

    Science.gov (United States)

    Mian, Rubina; Shelton-Rayner, Graham; Harkin, Brendan; Williams, Paul

    2003-03-01

    The aim of this study was to assess the effect of watching a psychological stressful event on the activation of leukocytes in healthy human volunteers. Blood samples were obtained from 32 healthy male and female subjects aged between 20 and 26 years before, during and after either watching an 83-minute horror film that none of the subjects had previously seen (The Texas Chainsaw Massacre, 1974) or by sitting quietly in a room (control group). Total differential cell counts, leukocyte activation as measured by the nitroblue tetrazolium (NBT) test, heart rate and blood pressure (BP) measurements were taken at defined time points. There were significant increases in peripheral circulating leukocytes, the number of activated circulating leukocytes, haemoglobin (Hb) concentration and haematocrit (Hct) in response to the stressor. These were accompanied by significant increases in heart rate, systolic and diastolic BP (P<0.05 from baseline). This is the first reported study on the effects of observing a psychologically stressful, albeit fictitious event on circulating leukocyte numbers and the state of leukocyte activation as determined by the nitrotetrazolium test.

  7. INTERNATIONAL MARKETING ACTIVITIES OF MULTINATIONAL COMPANIES IN CONDITIONS OF INSTABILITY

    Directory of Open Access Journals (Sweden)

    N. V. Lyasnikov

    2016-01-01

    Full Text Available This article describes the conceptual basis for the formation of international marketing, the characteristic of the main exit strategies on the world market, revealed features of international marketing that national companies are obliged to take into account the examples of international marketing strategies of international companies such as Apple, Google, Nike, the Russian company Natura Siberica.The purpose of this paper is to analyze the international marketing activities of multinational companies and the development of proposals for improving this process.Methodology. To complete this article, no such analysis methods were used as comparative and Economics and Statistics.Conclusions / relevance. The results are of practical value, they can be used in a lecture course teachers of educational institutions in the preparation of managers, as well as direct marketing specialists. In the study, the author was able to draw a number of conclusions that facilitate the development of the set of eff ective combinations, each of which represents a unique scenario of territorial expansion. Promising further expansion of the practice of implementation of marketing approaches in the organization of the entities of multinational companies, in Vol. H. The use of new technologies.

  8. One hundred prime references on hydrogeochemical and stream sediment surveying for uranium as internationally practiced, including 60 annotated references

    International Nuclear Information System (INIS)

    Sharp, R.R. Jr.; Bolivar, S.L.

    1981-04-01

    The United States Department of Energy (DOE), formerly the US ERDA, has initiated a nationwide Hydrogeochemical and Stream Sediment Reconnaissance (HSSR). This program is part of the US National Uranium Resource Evaluation, designed to provide an improved estimate for the availability and economics of nuclear fuel resources and make available to industry information for use in exploration and development of uranium resources. The Los Alamos National Laboratory is responsible for completing the HSSR in Rocky Mountain states of New Mexico, Colorado, Wyoming, and Montana and in the state of Alaska. This report contains a compilation of 100 prime references on uranium hydrogeochemical and stream sediment reconnaissance as internationally practiced prior to 1977. The major emphasis in selection of these references was directed toward constructing a HSSR program with the purpose of identifying uranium in the Los Alamos National Laboratory area of responsibility. The context of the annotated abstracts are the authors' concept of what the respective article contains relative to uranium geochemistry and hydrogeochemical and stream sediment surveying. Consequently, in many cases, significant portions of the original articles are not discussed. The text consists of two parts. Part I contains 100 prime references, alphabetically arranged. Part II contains 60 select annotated abstracts, listed in chronological order

  9. A comparison of important international and national standards for limiting exposure to EMF including the scientific rationale.

    Science.gov (United States)

    Roy, Colin R; Martin, Lindsay J

    2007-06-01

    A comparison of Eastern (from Russia, Hungary, Bulgaria, Poland, and the Czech Republic) and Western (represented by the International Commission on Non-Ionizing Radiation Protection guidelines and the Institute of Electrical and Electronic Engineers standards) radiofrequency standards reveals key differences. The Eastern approach is to protect against non-thermal effects caused by chronic exposure to low level exposure, and the occupational basic restriction is power load (the product of intensity and exposure duration). In contrast, the Western approach is to protect against established acute biological effects that could signal an adverse health effect, and the principal basic restriction is the specific absorption rate to protect against thermal effects. All of the standards are science-based, but a fundamental difference arises from a lack of agreement on the composition of the reference scientific database and of which adverse effect needs to be protected against. However, differences also exist between the ICNIRP and IEEE standards. An additional complication arises when standards are derived or modified using a precautionary approach. For ELF the differences between ICNIRP and IEEE are more fundamental; namely, differences in the basic restriction used (induced current; in-situ electric field) and the location of breakpoints in the strength-frequency curves result in large differences. In 2006, ICNIRP will initiate the review of their ELF and radiofrequency guidelines, and this will provide an opportunity to address differences in standards and the move towards harmonization of EMF standards and guidelines.

  10. 25 CFR 170.623 - How are IRR Program projects and activities included in a self-governance agreement?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false How are IRR Program projects and activities included in a self-governance agreement? 170.623 Section 170.623 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE... self-governance agreement? To include an IRR Program project or activity in a self-governance agreement...

  11. Present and future activities of the IAEA on internal dosimetry: Lessons learned from international intercomparisons

    International Nuclear Information System (INIS)

    Cruz Suarez, R.; Gustafsson, M.; Mrabit, K.

    2003-01-01

    The International Atomic Energy Agency (IAEA) conducts safety activities to support the assessment of occupational exposure due to intakes of radionuclides; a comprehensive set of safety documents will soon be completed. In recent years, extensive improvements in measurement techniques, phantoms and computational tools have been made. Thus, it is important for laboratories involved in internal dosimetry to undergo performance testing procedures to demonstrate the correctness of the methods applied and also to determine the consistency of their results with those obtained by other laboratories. Several intercomparisons were organised, and they revealed significant differences among laboratories in their approaches, methods and assumptions, and consequently in their results. This paper presents the current and future IAEA activities in support of assessment of occupational exposure due to intakes of radionuclides in the IAEA Member States, as well as the lessons learned from several intercomparison exercises in the last 5 years. (author)

  12. Activity behavior of a HPLC column including α-chymotrypsin immobilized monosized-porous particles

    International Nuclear Information System (INIS)

    Bilici, Z.; Camli, S.T.; Unsal, E.; Tuncel, A.

    2004-01-01

    In this study, a polymer-based, α-chymotrypsin (CT) immobilized HPLC column was prepared as a potential material for affinity-HPLC and chiral separation applications. Monosized-macroporous particles were synthesized as the support material by a relatively new polymerization protocol, the so-called, 'modified seeded polymerization'. The particles were obtained in the form of styrene-glycidyl methacrylate- divinylbenzene terpolymer approximately 11 μm in size. The particles were treated with aqueous ammonia to have primary amine groups on the porous surface. The amine functionalized particles were reacted by glutaraldehyde and the enzyme, CT, was covalently attached. CT carrying monosized-porous particles were slurry packed into the HPLC column 50 mmx4.6 mm in size. Since the activity behavior of immobilized CT played an important role in the enantiomeric separations performed by similar columns, the enzymatic activity behavior of the column produced by our protocol was determined. For this purpose, HPLC column was used as a packed bed reactor and the enzymatic reaction was continuously followed by measuring the absorbance of the output flow by the UV-detector of HPLC. S-shaped absorbance-time curves were obtained by monitoring the reactor output both in dynamic and steady-state periods. The columns with relatively lower immobilized enzyme content were more sensitive to the changes in the operating conditions and responded with more appreciable substrate conversion changes. The maximum reaction rate of the immobilized enzyme was estimated as approximately 25% of the free one by the mathematical model describing the activity behavior of the column. No significant loss was observed in the activity of the immobilized enzyme during the course of the experiments

  13. 50 CFR 23.15 - How may I travel internationally with my personal or household effects, including tourist souvenirs?

    Science.gov (United States)

    2010-10-01

    ... species is included, except for certain worked African elephant ivory as provided in paragraph (f) of this... within 1 year of changing your residence from one country to another. (4) The shipment, or shipments if..., inherited, or otherwise acquired before you changed your residence. (f) African elephant worked ivory. You...

  14. EERE-Supported International Activities in Latin America (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2010-05-01

    The Office of Energy Efficiency and Renewable Energy (EERE) is involved in a variety of international initiatives, partnerships, and events that promote greater understanding and use of renewable energy (RE) and energy efficiency (EE) worldwide. In support of the Energy and Climate Partnership of the Americas (ECPA), EERE is working with several Latin American countries to advance EE and RE deployment for economic growth, energy security, poverty relief, and disaster recovery goals. This fact sheet highlights those activities.

  15. Ex Vivo Activity of Endoperoxide Antimalarials, Including Artemisone and Arterolane, against Multidrug-Resistant Plasmodium falciparum Isolates from Cambodia

    Science.gov (United States)

    2014-10-01

    OCT 2014 2. REPORT TYPE N/A 3. DATES COVERED - 4. TITLE AND SUBTITLE Ex Vivo Activity of Endoperoxide Antimalarials , Including Artemisone...Prescribed by ANSI Std Z39-18 Ex Vivo Activity of Endoperoxide Antimalarials , Including Artemisone and Arterolane, against Multidrug-Resistant...potent antimalarial activity (2, 3). Despite having a rapid mecha- nism of action, artemisinin resistance eventually emerged and was first detected

  16. Gamma dose from activation of internal shields in IRIS reactor.

    Science.gov (United States)

    Agosteo, Stefano; Cammi, Antonio; Garlati, Luisella; Lombardi, Carlo; Padovani, Enrico

    2005-01-01

    The International Reactor Innovative and Secure is a modular pressurised water reactor with an integral design. This means that all the primary system components, such as the steam generators, pumps, pressuriser and control rod drive mechanisms, are located inside the reactor vessel, which requires a large diameter. For the sake of better reliability and safety, it is desirable to achieve the reduction of vessel embrittlement as well as the lowering of the dose beyond the vessel. The former can be easily accomplished by the presence of a wide downcomer, filled with water, which surrounds the core region, while the latter needs the presence of additional internal shields. An optimal shielding configuration is under investigation, for reducing the ex-vessel dose due to activated internals and for limiting the amount of the biological shielding. MCNP 4C calculations were performed to evaluate the neutron and the gamma dose during operation and the 60Co activation of various shields configurations. The gamma dose beyond the vessel from activation of its structural components was estimated in a shutdown condition, with the Monte Carlo code FLUKA 2002 and the MicroShield software. The results of the two codes are in agreement and show that the dose is sufficiently low, even without an additional shield.

  17. Gamma dose from activation of internal shields in IRIS reactor

    International Nuclear Information System (INIS)

    Agosteo, S.; Cammi, A.; Garlati, L.; Lombardi, C.; Padovani, E.

    2005-01-01

    The International Reactor Innovative and Secure is a modular pressurised water reactor with an integral design. This means that all the primary system components, such as the steam generators, pumps, pressurizer and control rod drive mechanisms, are located inside the reactor vessel, which requires a large diameter. For the sake of better reliability and safety, it is desirable to achieve the reduction of vessel embrittlement as well as the lowering of the dose beyond the vessel. The former can be easily accomplished by the presence of a wide downcomer, filled with water, which surrounds the core region, while the latter needs the presence of additional internal shields. An optimal shielding configuration is under investigation, for reducing the ex-vessel dose due to activated internals and for limiting the amount of the biological shielding. MCNP 4C calculations were performed to evaluate the neutron and the gamma dose during operation and the 60 Co activation of various shields configurations. The gamma dose beyond the vessel from activation of its structural components was estimated in a shutdown condition, with the Monte Carlo code FLUKA 2002 and the MicroShield software. The results of the two codes are in agreement and show that the dose is sufficiently low, even without an additional shield. (authors)

  18. International Centre for Theoretical Physics. Scientific activities in 1980

    International Nuclear Information System (INIS)

    1981-09-01

    The Centre's scientific programme for 1980 falling under five main fields, i.e. Physics and Energy, Physics and Technology, Physics and Frontiers of Knowledge, Applicable Mathematics and Planning Models, and Physics of the Environment and of Natural Resources, is briefly discussed. Participation in the research and training-for-research activities of the ICTP during 1980 and the stable resources for the period 1970 to 1981 are shown in tables. A detailed ''post-spectus'' of the seminars, meetings, and courses which the centre organized in 1980 is given. A list of titles of the preprints and internal reports produced during the year is also given for each area of activity

  19. International Centre for Theoretical Physics, Trieste. Scientific activities in 1993

    International Nuclear Information System (INIS)

    1994-10-01

    The annual report of the International Centre for Theoretical Physics from Trieste for 1993 contains four parts. Part I gives statistical data on the main activities of the Centre. Part II presents the scientific programme structured as follows: Fundamental physics, Condensed matter physics, Mathematics, Physics and energy, Physics and environment, Physics of the living state, Applied physics, Adriatico Research Conferences, Diploma Course, Laboratories, Long-term visitors, Network of Associate Members and Federal Institutes, Training and research at italian laboratories, External Activities, Science, High Technology and Development Programme, Meeting hosted, Awards. Part III lists the publications issued in 1993. Part IV presents the scientific support services. Tabs

  20. Active immunisation of horses against tetanus including the booster dose and its application.

    Science.gov (United States)

    Liefman, C E

    1981-02-01

    Successful active immunisation of horses against tetanus is dependent on a number of factors of which the toxoid preparation used, its method of application and the ability of the individual horse to respond are fundamental. Two immunisation schedules using an aluminium-based toxoid preparation were examined and the protection determined by monitoring the level of antitoxin afforded by each schedule. The results obtained demonstrated that 2 doses of this toxoid are necessary to ensure 12 months protection in all horses. These results are discussed in relation to the factors involved in active immunisation against tetanus. Reference is also made to the occurrence of a transient phase of reduced levels of antitoxin following booster doses of toxoid in immunised horses during which it is considered these horses could become more susceptible to tetanus. The effect of a booster dose on immunised horses was examined and while there can be a reduction in the level of antitoxin in some immunised horses following this dose its effect is minimal, short-lived and for all practical purposes can be disregarded. The application of the booster dose in practice is also discussed.

  1. In vitro activity of Inula helenium against clinical Staphylococcus aureus strains including MRSA.

    LENUS (Irish Health Repository)

    O'Shea, S

    2009-01-01

    The present study aims to investigate the bactericidal activity (specifically antistaphylococcal) of Inula helenium. The antimicrobial activity of the extract is tested against 200 clinically significant Irish Staphylococcus aureus isolates consisting of methicillin-resistant (MRSA) and -sensitive (MSSA) S. aureus using a drop test method and a microbroth dilution method. The antibacterial effect is evaluated by measuring the area of the inhibition zone against the isolates. Results proved I. helenium to be 100% effective against the 200 staphylococci tested, with 93% of isolates falling within the ++ and +++ groups. The minimum bactericidal concentration of I. helenium was examined on a subset of isolates and values ranged from 0.9 mg\\/mL to 9.0 mg\\/mL. The extract was equally effective against antibiotic-resistant and -sensitive strains. This plant therefore possesses compounds with potent antistaphylococcal properties, which in the future could be used to complement infection control policies and prevent staphylococcal infection and carriage. This research supports other studies wherein herbal plants exhibiting medicinal properties are being examined to overcome the problems of antibiotic resistance and to offer alternatives in the treatment and control of infectious diseases.

  2. International guidelines for fire protection at nuclear installations including nuclear fuel plants, nuclear fuel stores, teaching reactors, research establishments

    International Nuclear Information System (INIS)

    The guidelines are recommended to designers, constructors, operators and insurers of nuclear fuel plants and other facilities using significant quantities of radioactive materials including research and teaching reactor installations where the reactors generally operate at less than approximately 10 MW(th). Recommendations for elementary precautions against fire risk at nuclear installations are followed by appendices on more specific topics. These cover: fire protection management and organization; precautions against loss during construction alterations and maintenance; basic fire protection for nuclear fuel plants; storage and nuclear fuel; and basic fire protection for research and training establishments. There are numerous illustrations of facilities referred to in the text. (U.K.)

  3. Nuclear Rocket Test Facility Decommissioning Including Controlled Explosive Demolition of a Neutron-Activated Shield Wall

    International Nuclear Information System (INIS)

    Michael Kruzic

    2007-01-01

    Located in Area 25 of the Nevada Test Site, the Test Cell A Facility was used in the 1960s for the testing of nuclear rocket engines, as part of the Nuclear Rocket Development Program. The facility was decontaminated and decommissioned (D and D) in 2005 using the Streamlined Approach For Environmental Restoration (SAFER) process, under the Federal Facilities Agreement and Consent Order (FFACO). Utilities and process piping were verified void of contents, hazardous materials were removed, concrete with removable contamination decontaminated, large sections mechanically demolished, and the remaining five-foot, five-inch thick radiologically-activated reinforced concrete shield wall demolished using open-air controlled explosive demolition (CED). CED of the shield wall was closely monitored and resulted in no radiological exposure or atmospheric release

  4. Sixty Minutes of Physical Activity per Day Included Within Preschool Academic Lessons Improves Early Literacy.

    Science.gov (United States)

    Kirk, Stacie M; Kirk, Erik P

    2016-03-01

    The effects of increases in physical activity (PA) on early literacy skills in preschool children are not known. Fifty-four African-American preschool children from a low socioeconomic urban Head Start participated over 8 months. A 2-group, quasi-experimental design was used with one preschool site participating in the PA intervention and a second site participating as the control site. The PA program was designed to promote 300 minutes/week of moderate to vigorous PA academic lessons. Academic achievement related to early literacy and phonological awareness in the areas of rhyming and alliteration were assessed at baseline, 4 and 8 months. Over 8 months, rhyming significantly (p literacy. © 2016, American School Health Association.

  5. KINAC/INSA International Training Activities and Lessons Learned

    International Nuclear Information System (INIS)

    Kim, Hyun Chul

    2016-01-01

    In an effort to strengthen the coordination of the nuclear security training and support centers, the International Atomic Energy Agency (IAEA) established the International Network for Nuclear Security Training and Support Centres (NSSC Network) in February 2012. In February 2013, NSSC Network members from China, Japan and the Republic of Korea (ROK) established the 'Asia Regional Network' under the auspices of the NSSC Network to enhance regional collaboration to harmonize activities of the regional CoEs to provide effective support on nuclear security. Japan opened its CoE, Integrated Support Center for Nuclear Nonproliferation and Nuclear Security (ISCN) in February 2011. The Chinese CoE, so called State Nuclear Security Technology Center (SNSTC), is expected to open in March 2016. As one of ROK's national commitments at the 2010 NSS, the KINAC/INSA was established in 2014 in order to share ROK's expertise and support the Summit's mission. International training activities of the KINAC/INSA for two years have been introduced and the lessons learned from those activities have been identified. While the KINAC/INSA as the ROK's CoE has begun on the right foot, it still remains challenging to achieve real excellence in training. Such international training efforts of the KINAC/INSA will eventually contribute to the ROK acknowledged as a global leader in the area of nuclear nonproliferation and security and a nuclear supplier fulfilling responsibility on global nuclear nonproliferation and security regime

  6. KINAC/INSA International Training Activities and Lessons Learned

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyun Chul [Korea Institute of Nuclear Nonproliferation and Control, Daejeon (Korea, Republic of)

    2016-05-15

    In an effort to strengthen the coordination of the nuclear security training and support centers, the International Atomic Energy Agency (IAEA) established the International Network for Nuclear Security Training and Support Centres (NSSC Network) in February 2012. In February 2013, NSSC Network members from China, Japan and the Republic of Korea (ROK) established the 'Asia Regional Network' under the auspices of the NSSC Network to enhance regional collaboration to harmonize activities of the regional CoEs to provide effective support on nuclear security. Japan opened its CoE, Integrated Support Center for Nuclear Nonproliferation and Nuclear Security (ISCN) in February 2011. The Chinese CoE, so called State Nuclear Security Technology Center (SNSTC), is expected to open in March 2016. As one of ROK's national commitments at the 2010 NSS, the KINAC/INSA was established in 2014 in order to share ROK's expertise and support the Summit's mission. International training activities of the KINAC/INSA for two years have been introduced and the lessons learned from those activities have been identified. While the KINAC/INSA as the ROK's CoE has begun on the right foot, it still remains challenging to achieve real excellence in training. Such international training efforts of the KINAC/INSA will eventually contribute to the ROK acknowledged as a global leader in the area of nuclear nonproliferation and security and a nuclear supplier fulfilling responsibility on global nuclear nonproliferation and security regime.

  7. International nuclear data measurement activities. Newsletter No.3

    International Nuclear Information System (INIS)

    1998-12-01

    A survey is presented for various laboratories where nuclear data measurement facilities are applied to measure specific data. The laboratories are located in France (2 laboratories), in Germany (4 laboratories), in Japan (10 laboratories), in Russia (Institute of Physics and Power Engineering), in Sweden (Department of Neutron Research, Uppsala University), and in the USA (5 laboratories). Two international organizations are also included: Frank Laboratory of Neutron Physics, and Institute for Reference Materials and Measurements. (R.P.)

  8. Physical Activity of Croatian Population: Cross-sectional Study Using International Physical Activity Questionnaire

    OpenAIRE

    Jurakić, Danijel; Pedišić, Željko; Andrijašević, Mirna

    2009-01-01

    Aim To determine the physical activity level of the Croatian population in different domains of everyday life. Methods A random stratified sample of 1032 Croatians aged 15 years and older was interviewed using the official Croatian long version of the International Physical Activity Questionnaire (IPAQ). Total physical activity and physical activity in each of the 4 life domains – work, transport, domestic and garden, and leisure-time – were estimated. Physical activit...

  9. Stakeholder involvement in international conventions governing civil nuclear activities

    International Nuclear Information System (INIS)

    Emmerechts, Sam

    2017-01-01

    Mr Emmerechts explained that international conventions have varying positions on stakeholders and their involvement depending upon the intent of the legislator and the field they cover, ranging from a narrow to a broad interpretation. He addressed stakeholder involvement in two other international conventions governing civil nuclear activities, namely the Convention on Nuclear Safety, and the Joint Convention on the Safety of Spent Fuel Management and on the Safety of Radioactive Waste Management (the Joint Convention), both concluded under the auspices of the International Atomic Energy Agency (IAEA). He noted that the Convention on Nuclear Safety remains a 'traditional' international legal instrument, focusing on governments and governmental bodies as the main stakeholders and limiting obligations regarding the involvement of the public and intergovernmental organisations to their receiving information and observing. Likewise, the Joint Convention limits obligations regarding public involvement to access to information, notably as to the siting of proposed facilities. However, he noted that in the European Union, the Directive on Nuclear Safety (2014/87/Euratom) and the Directive for the Safe Management of Spent Fuel and Radioactive Waste (2011/70/Euratom) have more advanced public participation requirements in nuclear decision making. Mr Emmerechts explained that the substantial differences between nuclear legislation and the Aarhus and Espoo Conventions with regards to public involvement requirements could partly be explained by the technicality of nuclear information and by issues related to nuclear security

  10. porewater chemistry experiment at Mont Terri rock laboratory. Reactive transport modelling including bacterial activity

    International Nuclear Information System (INIS)

    Tournassat, Christophe; Gaucher, Eric C.; Leupin, Olivier X.; Wersin, Paul

    2010-01-01

    Document available in extended abstract form only. An in-situ test in the Opalinus Clay formation, termed pore water Chemistry (PC) experiment, was run for a period of five years. It was based on the concept of diffusive equilibration whereby traced water with a composition close to that expected in the formation was continuously circulated and monitored in a packed off borehole. The main original focus was to obtain reliable data on the pH/pCO 2 of the pore water, but because of unexpected microbially- induced redox reactions, the objective was then changed to elucidate the biogeochemical processes happening in the borehole and to understand their impact on pH/pCO 2 and pH in the low permeability clay formation. The biologically perturbed chemical evolution of the PC experiment was simulated with reactive transport models. The aim of this modelling exercise was to develop a 'minimal-' model able to reproduce the chemical evolution of the PC experiment, i.e. the chemical evolution of solute inorganic and organic compounds (organic carbon, dissolved inorganic carbon etc...) that are coupled with each other through the simultaneous occurrence of biological transformation of solute or solid compounds, in-diffusion and out-diffusion of solute species and precipitation/dissolution of minerals (in the borehole and in the formation). An accurate description of the initial chemical conditions in the surrounding formation together with simplified kinetics rule mimicking the different phases of bacterial activities allowed reproducing the evolution of all main measured parameters (e.g. pH, TOC). Analyses from the overcoring and these simulations evidence the high buffer capacity of Opalinus clay regarding chemical perturbations due to bacterial activity. This pH buffering capacity is mainly attributed to the carbonate system as well as to the clay surfaces reactivity. Glycerol leaching from the pH-electrode might be the primary organic source responsible for

  11. Asymmetric impacts of international energy shocks on macroeconomic activities

    International Nuclear Information System (INIS)

    Yeh, Fang-Yu; Hu, Jin-Li; Lin, Cheng-Hsun

    2012-01-01

    While limited by its scarcity of natural resources, the impacts of energy price changes on Taiwan's economic activities have been an important issue for social public and government authorities. This study applies the multivariate threshold model to investigate the effects of various international energy price shocks on Taiwan's macroeconomic activity. By separating energy price changes into the so-called decrease and increase regimes, we can realize different impacts of energy price changes and their shocks on economic output. The results confirm that there is an asymmetric threshold effect for the energy-output nexus. The optimal threshold levels are exactly where the oil price change is at 2.48%, the natural gas price change is at 0.66%, and the coal price change is at 0.25%. The impulse response analysis suggests that oil price and natural gas shocks have a delayed negative impact on macroeconomic activities. - Highlights: ► This study applies multivariate threshold model to investigate the effects of various international energy price shocks on Taiwan's macroeconomic activity. ► The results confirm that there is an asymmetric threshold effect for energy-output nexus. ► The optimal threshold levels are exactly found where oil price change is at 2.48%, natural gas price change is at 0.66%, and coal price change is at 0.25%.

  12. Ozone control of biological activity during Earth's history, including the KT catastrophe

    Science.gov (United States)

    Sheldon, W. R.

    1994-01-01

    There have been brief periods since the beginning of the Cambrian some 600 m.y. ago when mass extinctions destroyed a significant fraction of living species. The most widely studied of these events is the catastrophe at the KT boundary that ended the long dominance of the dinosaurs. In addition to mass extinctions, there is another profound discontinuity in the history of Earth's biota, the explosion of life at the end of the Precambrian era which is an episode that is not explained well at all. For some 3 b.y. before the Cambrian, life had been present on Earth, but maintained a low level of activity which is an aspect of the biota that is puzzling, especially during the last two-thirds of that period. During the last 2 b.y. before the Cambrian, conditions at the Earth's surface were suitable for a burgeoning of the biota, according to most criteria: the oceans neither boiled nor were fozen solid during this time, and the atmosphere contained sufficient O for the development of animals. The purpose of this paper is to suggest that mass extinctions and the lackluster behavior of the Precambrian biota share a common cause: an inadequate amount of ozone in the atmosphere.

  13. NanoSPD activity in Ufa and International Cooperation

    International Nuclear Information System (INIS)

    Reshetnikova, N; Salakhova, M

    2014-01-01

    This report presents main achievements of R and D activities of the Institute of Physics of Advanced Materials of Ufa State Aviation Technical University (IPAM USATU, Ufa, Russia) with a special attention to innovative potential of nanostructured metals and alloys produced by the severe plastic deformation (SPD) techniques. Several examples of the first promising applications of bulk nanostructured materials (BNM) as well as potential competing technologies are considered and discussed. The authors would like to focus special emphasis on international cooperation in view of numerous emerging projects as well as different conferences and seminars that pave the way to close and fruitful cooperation, working visits and exchange of young scientists. The possibilities of international cooperation through various foundations and programs are considered

  14. International Year of Planet Earth - Accomplishments, Activities, Challenges and Plans in Mexico

    Science.gov (United States)

    Fucugauchi, J. U.; Perez-Cruz, L. L.; Alaniz-Alvarez, S.

    2009-12-01

    The International Year of Planet Earth started as a joint initiative by UNESCO and IUGS with the participation of several geosciences organizations, and developed into a major international geosciences program for the triennium 2007-2009, with the inclusion and participation of national and regional committees. In this presentation we focus on current activities and plans in our country and the participation in international activities. Mexican community has been part of international programs since the International Geophysical Year, continuing through its participation in other programs, e.g., Upper Mantle, Geodynamics, Lithosphere, IHY, IPY and eGY. IYPE activities have concentrated in publications, OneGeology, radio/TV programs, organization of conferences, meetings and outreach events. A book series on Earth Science Experiments for Children has been edited, with first books published on “Atmospheric Pressure and Free Fall of Objects”, “Light and Colors”, “Standing on Archimedes”, “Foucault and Climate” and “Earth and its Waves “. Books are distributed to schools, with tens of thousand copies distributed nationwide and new editions underway. Other publications include leaflets, books and special El Faro issues (edited by the National University) and articles in other journals. In 2007 the AGU Joint Assembly with international participation from US, Canada, Europe and Latin America was held in Acapulco. Current plans include an electronic open-access journal, additional publications of the Planet Earth series, articles and special issues in journals and magazines, plus events on selected themes from the IYPE science program, particularly on Megacities, Hazards, Resources and Biodiversity. Mexico City metropolitan area, with > 22 million inhabitants presents special challenges, being at high altitude within an active tectonic and volcanic area requiring major efforts in water supply, water control, rains and waste disposal and management

  15. COSPAR/PRBEM international working group activities report

    Science.gov (United States)

    Bourdarie, S.; Blake, B.; Cao, J. B.; Friedel, R.; Miyoshi, Y.; Panasyuk, M.; Underwood, C.

    It is now clear to everybody that the current standard AE8 AP8 model for ionising particle specification in the radiation belts must be updated But such an objective is quite difficult to reach just as a reminder to develop AE8 AP8 model in the seventies was 10 persons full time for ten years It is clear that world-wide efforts must be combined because not any individual group has the human resource to perform these new models by themselves Under COSPAR umbrella an international group of expert well distributed around the world has been created to set up a common framework for everybody involved in this field Planned activities of the international group of experts are to - Define users needs - Provide guidelines for standard file format for ionising measurements - Set up guidelines to process in-situ data on a common basis - Decide in which form the new models will have to be - Centralise all progress done world-wide to advise the community - Try to organise world-wide activities as a project to ensure complementarities and more efficiencies between all efforts done Activities of this working group since its creation will be reported as well as future plans

  16. 45 CFR 287.130 - Can NEW Program activities include job market assessments, job creation and economic development...

    Science.gov (United States)

    2010-10-01

    ... assessments, job creation and economic development activities? 287.130 Section 287.130 Public Welfare... creation and economic development activities? (a) A Tribe may conduct job market assessments within its NEW Program. These might include the following: (1) Consultation with the Tribe's economic development staff...

  17. International oil and gas exploration and development activities

    Energy Technology Data Exchange (ETDEWEB)

    1990-10-29

    This report is part of an ongoing series of quarterly publications that monitors discoveries of oil and natural gas in foreign countries and provides an analysis of the reserve additions that result. The report is prepared by the Energy Information Administration (EIA) of the US Department of Energy (DOE) under the Foreign Energy Supply Assessment Program (FESAP). It presents a summary of discoveries and reserve additions that result from recent international exploration and development activities. It is intended for use by petroleum industry analysts, various government agencies, and political leaders in the development, implementation, and evaluation of energy plans, policy, and legislation. 25 refs., 8 figs., 4 tabs.

  18. Analysis of graphic representations of activity theory in international journals

    Directory of Open Access Journals (Sweden)

    Marco André Mazzarotto

    2016-05-01

    Full Text Available Activity theory is a relevant framework for the Design field, and their graphic representations are cognitive artifacts that aid the understanding, use and communication of this theory. However, there is a lack of consistency around the graphics and labels used in these representations. Based on this, the aim of this study was to identify, analyze and evaluate these differences and propose a representation that aims to be more suitable for the theory. For this, uses as method a literature review based on Engeström (2001 and its three generations of visual models, combined with graphical analysis of representations collected in a hundred papers from international journals.

  19. International intercomparison of neutron spectra evaluating methods using activation detectors

    International Nuclear Information System (INIS)

    Fischer, A.

    1975-06-01

    The international intercomparison of neutron spectrum evaluation methods using activation detectors was organized by the IAEA in 1971 - 1972. All of the contributions and the results of a critical evaluation are presented here. The spectra of different contributors are compared to a reference spectrum by means of different integrals and weighting functions. Different cross section sets, foil numbers, energy point systems, guess spectra used by the contributors cause differences in the resulting spectra. The possible ways of separating these effects are also investigated. Suggestions are made for the organization of a new intercomparison on the basis of more uniform input data. (orig.) [de

  20. Mission and activities of the International Commission on Radiological Protection

    International Nuclear Information System (INIS)

    Clements, C.H.

    2018-01-01

    The International Commission on Radiological Protection (ICRP), formed in 1928, develops the System of Radiological Protection for the public benefit. The objective of the recommendations is to contribute to an appropriate level of protection for people and the environment against the harmful effects of radiation exposure without unduly limiting the individual or societal benefits of activities involving radiation. In developing its recommendations, ICRP considers advances in scientific knowledge, evolving social values, and practical experience. These recommendations are the basis of radiological protection standards and practice worldwide

  1. International Centre for Theoretical Physics, Trieste Scientific activities in 1991

    International Nuclear Information System (INIS)

    1992-11-01

    The document contains three parts. Part 1 is a general review of the scientific activities of the Centre in 1991, including a statistical digest. Part II presents the scientific programme of the Centre in the following fields: Fundamental Physics, Condensed Matter Physics, Mathematics, Physics and Energy, Physics and Environment, Applied Physics, Adriatico Research Conferences, as well as other aspects of the Centre activities in 1991. Part III lists the publications issued in 1991. Tabs

  2. International Centre for Theoretical Physics, Trieste: Scientific activities in 1989

    International Nuclear Information System (INIS)

    1990-09-01

    The document contains three parts. Part I is a general review of the scientific activities in 1989 including a statistical digest. Part II describes the scientific programme in Fundamental Physics, Condensed Matter Physics, Mathematics, Physics and Energy, Physics and Environment, Applied Physics, Physics of the Space, Adriatico Research Conferences and other aspects of the Centre activities. Part III lists the publications issued in 1989. Tabs

  3. International Centre for Theoretical Physics, Trieste. Scientific activities in 1990

    International Nuclear Information System (INIS)

    1991-09-01

    The document contains three parts: Part I is a general review of the scientific activities of the Centre in 1990, including a statistical digest. Part II describes the scientific programme of the Centre in the following fields: Fundamental physics, condensed nuclear physics, mathematics, physics and energy, physics and environment, physics of the living state, applied physics Adriatico research conferences and other aspects of the Centre activities. Part III lists the publications issued in 1990

  4. Development of the International Spinal Cord Injury Activities and Participation Basic Data Set

    DEFF Research Database (Denmark)

    Post, M W; Charlifue, S; Biering-Sørensen, F

    2016-01-01

    on a three-point scale for each item completes the total of 24 A&P variables. CONCLUSION: Collection of the International SCI A&P Basic Data Set variables in all future research on SCI outcomes is advised to facilitate comparison of results across published studies from around the world. Additional......STUDY DESIGN: Consensus decision-making process. OBJECTIVES: The objective of this study was to develop an International Spinal Cord Injury (SCI) Activities and Participation (A&P) Basic Data Set. SETTING: International working group. METHODS: A committee of experts was established to select...... and define A&P data elements to be included in this data set. A draft data set was developed and posted on the International Spinal Cord Society (ISCoS) and American Spinal Injury Association websites and was also disseminated among appropriate organizations for review. Suggested revisions were considered...

  5. International Centre for Theoretical Physics, Trieste, scientific activities in 1992

    International Nuclear Information System (INIS)

    1993-08-01

    The document contains three parts. Part I is a programme overview of 1992 including a description of scientific activities and statistics about participation by geographic areas and by activities. Part II presents the scientific programme in the following fields: fundamental physics, condensed matter physics, mathematics, physics related to the energy problems, physics and the environment, physics of the living state (of matter), and applied physics. Conferences and other activities by the centre are also listed. Part III lists the publications issued in 1992. 5 tabs

  6. A novel synthetic quantification standard including virus and internal report targets: application for the detection and quantification of emerging begomoviruses on tomato

    OpenAIRE

    Péréfarres, Frédéric; Hoareau, Murielle; Chiroleu, Frédéric; Reynaud, Bernard; Dintinger, Jacques; Lett, Jean-Michel

    2011-01-01

    Abstract Background Begomovirus is a genus of phytopathogenic single-stranded DNA viruses, transmitted by the whitefly Bemisia tabaci. This genus includes emerging and economically significant viruses such as those associated with Tomato Yellow Leaf Curl Disease, for which diagnostic tools are needed to prevent dispersion and new introductions. Five real-time PCRs with an internal tomato reporter gene were developed for accurate detection and quantification of monopartite begomoviruses, inclu...

  7. Multi trace element analysis of dry biological materials by neutron activation analysis including a chemical group separation

    International Nuclear Information System (INIS)

    Weers, C.A.

    1980-07-01

    Multi-element analysis of dry biological material by neutron activation analysis has to include radiochemical separation. The evaporation process is described in terms of the half-volume. The pretreatment of the samples and the development of the destruction-evaporation apparatus are described. The successive adsorption steps with active charcoal, Al 2 O 3 and coprecipitation with Fe(OH) 3 are described. Results obtained for standard reference materials are summarized. (G.T.H.)

  8. Inventory of U.S.-led International Activities on Building Energy Efficiency Initial Findings

    Energy Technology Data Exchange (ETDEWEB)

    Delgado, Alison; Evans, Meredydd

    2010-04-01

    Several U.S. Government agencies promote energy efficiency in buildings internationally. The types and scope of activities vary by agency. Those with the largest role include the U.S. Agency for International Development (USAID), the U.S. Department of State and the Environmental Protection Agency (EPA). Both USAID and the Department of State have a substantial presence overseas, which may present some complementarities with the Department of Energy’s efforts to reach out to other countries. Generally speaking, USAID focuses on capacity building and policy issues; the Department of State focuses on broad diplomatic efforts and some targeted grants in support of these efforts, and EPA has more targeted roles linked to ENERGY STAR appliances and a few other activities. Several additional agencies are also involved in trade-related efforts to promote energy efficiency in buildings. These include the Department of Commerce, the Export-Import Bank, the Overseas Private Investment Corporation and the Trade and Development Agency (TDA). This initial synthesis report is designed to summarize broad trends and activities relating to international cooperation on energy efficiency in buildings, which can help the U.S. Department of Energy (DOE) in developing its own strategy in this area. The Pacific Northwest National Laboratory will develop a more complete synthesis report later in 2010 as it populates a database on international projects on building energy efficiency.

  9. Quality assurance activities and proposals at the international level

    International Nuclear Information System (INIS)

    Davison, M.

    1985-01-01

    A number of international bodies have attempted to stimulate wider interest in Quality Assurance in X-ray departments. A major initiative has been taken by WHO with the publication of its recommendations in 1982 under the title Quality Assurance in Diagnostic Radiology, in which they indicated the action that should be taken at various national, professional and local levels. The recommendations of ICRP in Publication 26 point to the need for quality assurance programmes that will obtain optimum diagnostic information at minimum cost and minimum patient dose. ICRU have been considering the need for cost-effective quality assurance programmes and the specification of standards for image quality. The IEC and various manufacturers' organisations have begun to consider the part they can play in setting up quality control procedures. The most active group has been the ISRRT, which has arranged a series of seminars and workshops for radiographers in various parts of the world. Future needs for international support lie in the provision of training programmes, the publication of comparative statistical data and the development of image quality standards. (author)

  10. International Activities in Radiation-Induced Carcinogenesis. Survey Paper

    Energy Technology Data Exchange (ETDEWEB)

    Komarov, E. [World Health Organization, Geneva (Switzerland)

    1969-11-15

    During the past 10 years special attention has been paid to the problem of late effects of radiation and in particular to radiation-induced carcinogenesis and leukaemogenesis. In the UNSCEAR report of 1958-1962 this.problem was mentioned as being of considerable importance from the point of view of estimation of risk to the population from environmental radiation. In 1964 a special report was prepared by UNSCEAR on radiation- induced carcinogenesis. In the ICRP publication No. 8, a chapter dealing with assessment of somatic risks discussed the problem of leukaemia and other neoplasms and particularly stressed the problem of thyroid carcinoma-and bone sarcoma. WHO panels of experts discussed the problem in 1960-1966 and made some recommendations for international activity in this field. In spite of the amount of scientific attention that has been given in recent years to experimental radiobiology in animals and lower forms, it has become abundantly clear that information directly applicable to humans is woefully inadequate and that there is a desperate need for carefully collected data from man on which to base public health planning and day to day work in radiation protection. This has long been recognized in the technical program of WHO in the emphasis given to the practical importance of epidemiology in human radiobiology and the degree to which it depends upon international collaboration.

  11. Market risk stress testing for internationally active financial institutions

    Directory of Open Access Journals (Sweden)

    Marković Petar

    2011-01-01

    Full Text Available The paper develops a comprehensive framework for market risk stress testing in internationally active financial institutions. We begin by defining the scope and type of the stress test and explaining how to select risk factors and the stress time horizon. We then address challenges related to data gathering, followed by in-depth discussion of techniques for developing realistic shock scenarios. Next the process of shock application to a particular portfolio is described, followed by determination of portfolio profit and loss. We conclude by briefly discussing the issue of assigning probability to stress scenarios. We illustrate the framework by considering the development of a ‘worst case’ scenario using global financial market data from Thomson Reuters Datastream.

  12. International petroleum licensing, exploration activity and fiscal terms

    International Nuclear Information System (INIS)

    Hodgshon, S.

    1994-01-01

    Although there is no decline in current international petroleum licensing activity, attention is drawn to the fact that it is concentrated in certain countries, many of them amongst the less geologically prospective. Among the factors other then geological prospectivity which promote a successful licensing and exploration environment, the most important is the fiscal terms offered. While countries which are highly prospective geologically may stiffen terms and still attract exploration companies because they feel they can make major discoveries, any decline in prospectivity needs to be accompanied by a matching change in fiscal terms to maintain interest. Less prospective countries which, hitherto, have created favourable investment conditions may however find that further declines cannot be reversed by attractive fiscal terms. (7 figures, 3 tables). (UK)

  13. The international ISOE programme. ISOE IAEA technical centre activities

    International Nuclear Information System (INIS)

    Gustafsson, M.

    1996-01-01

    The objective of the sub-programme on Occupational Radiation Protection in the International Atomic Energy Agency, IAEA, is to promote a harmonized approach to optimizing occupational radiation protection by developing guidelines for controlling radiation doses in the workplace and on current occupational radiation protection techniques. A significant part of this programme is the provision of assistance to developing member states to bring their radiation safety infrastructure to an appropriate level for the usage of radiation in the state. In consistence with these objectives the IAEA has been involved with the ISOE programme from its inception and has contributed actively to its growth. In 1993 an arrangement was agreed between the IAEA and the Nuclear Energy Agency, NEA, by which the IAEA co-sponsors ISOE inviting those IAEA member states which are not members of the NEA to participate cost-free in the programme. (author)

  14. Influence Factors of Sexual Activity for Internal Migrants in China

    Directory of Open Access Journals (Sweden)

    Junguo Zhang, PhD candidate

    2018-06-01

    Full Text Available Background: Sexual frequency is associated with the quality of life. China’s internal migrants that are sexually active are more likely to participate in sexual behavior. However, less work has been undertaken to assess the sexual frequency and its predictors in migrants. Aim: This study seeks to explore which factors were related to sexual frequency in migrants and how the association varies with different levels of sexual frequency. Methods: A total of 10,834 men and 4,928 women aged 20–49 years from 5 cities in China were enrolled by multi-stage sampling during August 2013–August 2015. Outcomes: Sexual frequency among migrants was determined by asking: How many times have you had sexual intercourse with a man/woman in the past 30 days? Results: In this study, sexual frequency with an average age of 38.28 years was 5.06 (95% CI 5.01–5.11 time per month. Negative binomial showed that male gender, younger age, earlier age of sexual debut, masturbation, more knowledge of sexual and reproductive health, longer time together with a spouse, and higher school education and incomes were predictors of increased sexual frequency in migrants. Communicating with sexual partners frequently had the largest effect on sexual frequency compared with occasional communicating (β = 0.2419, incidence rate ratio = 1.27, 95% CI 1.23–1.31. In the quantile regression, months of cohabitation (β = 0.0999, 95% CI 0.08–0.12, frequent sexual communication (β = 0.4534, 95% CI 0.39–0.52, and masturbation (β = 0.2168, 95% CI 0.14–0.30 were positively related to lower levels of sexual frequency. Interestingly, migrants who had low and high sexual frequency would be affected in opposite directions by the knowledge of sexual and reproductive health. Clinical Translation: Clinicians can more understand the relationship between sexual frequency and its factors that can as the symptom basis of sexually-related diseases. Conclusions: The present findings

  15. Effects of Leisure Education Programme Including Sportive Activities on Perceived Freedom in Leisure of Adolescents with Intellectual Disabilities

    Science.gov (United States)

    Ertuzun, Ezgi

    2015-01-01

    The objective of this experimental study is to determine the effect of leisure education programme including sportive activities on the perceived freedom in leisure of adolescents with mild intellectual disabilities. The research was designed with an experimental group (n = 37) and a control group (n = 34), and was conducted among a total of 71…

  16. The FARE: A new way to express FAlls Risk among older persons including physical activity as a measure of Exposure

    NARCIS (Netherlands)

    Wijlhuizen, G.J.; Chorus, A.M.J.; Hopman-Rock, M.

    2010-01-01

    Background: Common expressions of falls risk do not include exposure to hazards. We compared two expressions: the commonly used population incidence (fallers per 1000 person-years) and the FARE (FAlls Risk by Exposure): the number of fallers per 1000 physically active person-days. Methods:

  17. The FARE: a new way to express FAlls Risk among older persons including physical activity as a measure of exposure

    NARCIS (Netherlands)

    Wijlhuizen, G.J.; Chorus, A.M.J.; Hopman-Rock, M.

    2010-01-01

    Background: Common expressions of falls risk do not include exposure to hazards. We compared two expressions: the commonly used population incidence (fallers per 1000 person-years) and the FARE (FAlls Risk by Exposure): the number of fallers per 1000 physically active person-days. Methods:

  18. The association between school-based physical activity, including physical education, and academic performance: a systematic review of the literature.

    Science.gov (United States)

    Rasberry, Catherine N; Lee, Sarah M; Robin, Leah; Laris, B A; Russell, Lisa A; Coyle, Karin K; Nihiser, Allison J

    2011-06-01

    The purpose of this review is to synthesize the scientific literature that has examined the association between school-based physical activity (including physical education) and academic performance (including indicators of cognitive skills and attitudes, academic behaviors, and academic achievement). Relevant research was identified through a search of nine electronic databases using both physical activity and academic-related search terms. Forty-three articles (reporting a total of 50 unique studies) met the inclusion criteria and were read, abstracted, and coded for this synthesis. Findings of the 50 studies were then summarized. Across all the studies, there were a total of 251 associations between physical activity and academic performance, representing measures of academic achievement, academic behavior, and cognitive skills and attitudes. Slightly more than half (50.5%) of all associations examined were positive, 48% were not significant, and 1.5% were negative. Examination of the findings by each physical activity context provides insights regarding specific relationships. Results suggest physical activity is either positively related to academic performance or that there is not a demonstrated relationship between physical activity and academic performance. Results have important implications for both policy and schools. Copyright © 2010 Elsevier Inc. All rights reserved.

  19. Case law. Administrative decisions. National legislative and regulatory activities. International regulatory activities

    International Nuclear Information System (INIS)

    Anon.

    2007-01-01

    The different subjects are as follow: judgment on Konrad repository project (Germany), Measures for the dismantling of Barsebaeck (Sweden), amendment to the criminal code (Argentina), Australian nuclear science and technology organisation amendment act, commonwealth radioactive waste management legislation amendment (Australia), amendments to the radiation act and radiation decree (Finland), decree on securing financing for nuclear charges, decree licensing the construction of the basic nuclear installation Flamanville 3 comprising an EPR reactor (France), amendment to the act on preventive radiation protection, administrative provisions on the supervision of environmental radioactivity, ordinance on radioactive drugs, amendment to the ordinance on the treatment of foodstuffs with radiation, European agreement relating to the international transportation of dangerous goods by road, ordinance on the transportation of dangerous goods by road and rail, ordinance to amend the R.I.D. regulations, ordinance on the transportation of dangerous goods on the Rhine and Mosel rivers, amendments to the 1961 foreign trade act and to the 1993 foreign trade ordinance (Germany), regulations in the field of radiation protection (Iceland), decree on nuclear reactor licensing (Indonesia), carriage of dangerous goods by road act (Ireland), decree on emergency planning with regard to the transport of radioactive and fissile materials (Italy), covenant between the government and the Borssele operator concerning the life extension (Netherlands), consolidated edition of the 1965 radiation protection act (New Zealand), regulation on ionizing radiation sources (Poland), decision approving the structure and organisation of the romanian nuclear agency, amendment of the 2003 decision approving the internal rules of the national commission for the control of nuclear activities, amendment of the 2003 ordinance on the management of spent nuclear fuel and radioactive waste including final disposal

  20. Mouse preimplantation embryo responses to culture medium osmolarity include increased expression of CCM2 and p38 MAPK activation

    Directory of Open Access Journals (Sweden)

    Watson Andrew J

    2007-01-01

    Full Text Available Abstract Background Mechanisms that confer an ability to respond positively to environmental osmolarity are fundamental to ensuring embryo survival during the preimplantation period. Activation of p38 mitogen-activated protein kinase (MAPK occurs following exposure to hyperosmotic treatment. Recently, a novel scaffolding protein called Osmosensing Scaffold for MEKK3 (OSM was linked to p38 MAPK activation in response to sorbitol-induced hypertonicity. The human ortholog of OSM is cerebral cavernous malformation 2 (CCM2. The present study was conducted to investigate whether CCM2 is expressed during mouse preimplantation development and to determine whether this scaffolding protein is associated with p38 MAPK activation following exposure of preimplantation embryos to hyperosmotic environments. Results Our results indicate that Ccm2 along with upstream p38 MAPK pathway constituents (Map3k3, Map2k3, Map2k6, and Map2k4 are expressed throughout mouse preimplantation development. CCM2, MAP3K3 and the phosphorylated forms of MAP2K3/MAP2K6 and MAP2K4 were also detected throughout preimplantation development. Embryo culture in hyperosmotic media increased p38 MAPK activity in conjunction with elevated CCM2 levels. Conclusion These results define the expression of upstream activators of p38 MAPK during preimplantation development and indicate that embryo responses to hyperosmotic environments include elevation of CCM2 and activation of p38 MAPK.

  1. International Space Station (ISS) Internal Active Thermal Control System (IATCS) New Biocide Selection, Qualification and Implementation

    Science.gov (United States)

    Wilson, Mark E.; Cole, Harold E.; Rector, Tony; Steele, John; Varsik, Jerry

    2011-01-01

    The Internal Active Thermal Control System (IATCS) aboard the International Space Station (ISS) is primarily responsible for the removal of heat loads from payload and system racks. The IATCS is a water based system which works in conjunction with the EATCS (External ATCS), an ammonia based system, which are interfaced through a heat exchanger to facilitate heat transfer. On-orbit issues associated with the aqueous coolant chemistry began to occur with unexpected increases in CO2 levels in the cabin. This caused an increase in total inorganic carbon (TIC), a reduction in coolant pH, increased corrosion, and precipitation of nickel phosphate. These chemical changes were also accompanied by the growth of heterotrophic bacteria that increased risk to the system and could potentially impact crew health and safety. Studies were conducted to select a biocide to control microbial growth in the system based on requirements for disinfection at low chemical concentration (effectiveness), solubility and stability, material compatibility, low toxicity to humans, compatibility with vehicle environmental control and life support systems (ECLSS), ease of application, rapid on-orbit measurement, and removal capability. Based on these requirements, ortho-phthalaldehyde (OPA), an aromatic dialdehyde compound, was selected for qualification testing. This paper presents the OPA qualification test results, development of hardware and methodology to safely apply OPA to the system, development of a means to remove OPA, development of a rapid colorimetric test for measurement of OPA, and the OPA on-orbit performance for controlling the growth of microorganisms in the ISS IATCS since November 3, 2007.

  2. International study of objectively measured physical activity and sedentary time with body mass index and obesity

    DEFF Research Database (Denmark)

    Dyck, D Van; Cerin, E; De Bourdeaudhuij, I

    2015-01-01

    Background:Physical activity (PA) has been consistently implicated in the etiology of obesity, whereas recent evidence on the importance of sedentary time remains inconsistent. Understanding of dose-response associations of PA and sedentary time with overweight and obesity in adults can be improved...... effects of study site and gender.Methods:Data from the International Physical activity and the Environment Network (IPEN) Adult study were used. IPEN Adult is an observational multi-country cross-sectional study, and 12 sites in 10 countries are included. Participants wore an accelerometer for seven...

  3. Overview of the PPPL International Experimental Stellarator Collaboration Activity

    Energy Technology Data Exchange (ETDEWEB)

    Gates, David [Princeton University

    2012-03-28

    PPPL has initiated and strengthened collaborative experimental programs aimed at developing the required toolsets and scientific knowledge for advancing stellarators as a viable fusion energy source. In particular, activities at LHD and W7-X, the two large superconducting helical confinement systems in the world, have been expanded. The focus at LHD has been on diagnostic development and data analysis, since the device is a mature research facility with more than 20MW of heating power available. High beta stability experiments, ion and electron temperature measurements using a recently installed imaging x-ray crystal spectrometer, and 3D equilibrium reconstructions will be described. The focus on W7-X has been to develop hardware capabilities for divertor heat flux control, including plasma-facing components, error field correction coils, and power supplies. Progress on these and other activities will be presented.

  4. IAEA laboratory activities. The IAEA laboratories at Vienna and Seibersdorf, the International Laboratory of Marine Radioactivity at Monaco, the International Centre for Theoretical Physics at Trieste, the Middle Eastern Regional Radioisotope Centre for the Arab Countries, Cairo. 3rd report

    International Nuclear Information System (INIS)

    1966-01-01

    This third 'IAEA Laboratory Activities' report describes development and work during the year 1965. It includes activities of the IAEA Laboratories at Vienna and Seibersdorf, the International Laboratory of Marine Radioactivity at Monaco, the International Centre for Theoretical Physics at Trieste, and the Middle Eastern Regional Radioisotope Centre for the Arab Countries at Cairo

  5. IAEA Laboratory activities. The IAEA Laboratories at Vienna and Seibersdorf, the International Laboratory of Marine Radioactivity at Monaco, the International Centre for Theoretical Physics at Trieste, the Middle Eastern Regional Radioisotope Centre for the Arab Countries, Cairo. Sixth report

    International Nuclear Information System (INIS)

    1969-01-01

    This sixth 'IAEA Laboratory Activities' report describes development and work during the year 1968. It includes activities of the IAEA Laboratories at Vienna and Seibersdorf, the International Laboratory of Marine Radioactivity at Monaco, the International Centre for Theoretical Physics at Trieste, and the Middle Eastern Regional Radioisotope Centre for the Arab Countries at Cairo. (author)

  6. IAEA Laboratory activities. The IAEA Laboratories at Vienna and Seibersdorf, the International Laboratory of Marine Radioactivity at Monaco, the International Centre for Theoretical Physics at Trieste, the Middle Eastern Regional Radioisotope Centre for the Arab Countries, Cairo. Fourth report

    International Nuclear Information System (INIS)

    1967-01-01

    This fourth 'IAEA Laboratory Activities' report describes development and work during the year 1966. It includes activities of the IAEA Laboratories at Vienna and Seibersdorf, the International Laboratory of Marine Radioactivity at Monaco, the International Centre for Theoretical Physics at Trieste, and the Middle Eastern Regional Radioisotope Centre for the Arab Countries at Cairo. (author)

  7. Long-Term International Space Station (ISS) Risk Reduction Activities

    Science.gov (United States)

    Fodroci, M. P.; Gafka, G. K.; Lutomski, M. G.; Maher, J. S.

    2012-01-01

    As the assembly of the ISS nears completion, it is worthwhile to step back and review some of the actions pursued by the Program in recent years to reduce risk and enhance the safety and health of ISS crewmembers, visitors, and space flight participants. While the initial ISS requirements and design were intended to provide the best practicable levels of safety, it is always possible to further reduce risk - given the determination, commitment, and resources to do so. The following is a summary of some of the steps taken by the ISS Program Manager, by our International Partners, by hardware and software designers, by operational specialists, and by safety personnel to continuously enhance the safety of the ISS, and to reduce risk to all crewmembers. While years of work went into the development of ISS requirements, there are many things associated with risk reduction in a Program like the ISS that can only be learned through actual operational experience. These risk reduction activities can be divided into roughly three categories: Areas that were initially noncompliant which have subsequently been brought into compliance or near compliance (i.e., Micrometeoroid and Orbital Debris [MMOD] protection, acoustics) Areas where initial design requirements were eventually considered inadequate and were subsequently augmented (i.e., Toxicity Hazard Level- 4 [THL] materials, emergency procedures, emergency equipment, control of drag-throughs) Areas where risks were initially underestimated, and have subsequently been addressed through additional mitigation (i.e., Extravehicular Activity [EVA] sharp edges, plasma shock hazards) Due to the hard work and cooperation of many parties working together across the span of more than a decade, the ISS is now a safer and healthier environment for our crew, in many cases exceeding the risk reduction targets inherent in the intent of the original design. It will provide a safe and stable platform for utilization and discovery for years

  8. Neutron activation analysis method - international ring test for proficiency assessment

    International Nuclear Information System (INIS)

    Barbos, D.; Bucsa, A. F.

    2016-01-01

    The main objective of this test is to assess the quality control of analytical procedures for soils and plants which is of utmost importance to produce reliable and reproducible analytical data. For this purpose first, second, and third line quality control measures are taken in analytical laboratories. For first line control certified reference materials (CRM's) are preferred. However, the number and matrix variation in CRM's for environmental analytical research is still very limited. For second line control internal reference samples are often used, but again here the values for many element and parameter concentrations are questionable since almost no check versus CRM's is possible. For third line control participation in laboratory-evaluating exchange programs is recommended. This article contains the results achieved by our neutron activation analysis laboratory after irradiation experiment of soil and vegetation samples in TRIGA Reactor. All the samples were irradiated in the same location of the reactor in roughly similar conditions. (authors)

  9. Major features of immunesenescence, including reduced thymic output, are ameliorated by high levels of physical activity in adulthood.

    Science.gov (United States)

    Duggal, Niharika Arora; Pollock, Ross D; Lazarus, Norman R; Harridge, Stephen; Lord, Janet M

    2018-04-01

    It is widely accepted that aging is accompanied by remodelling of the immune system including thymic atrophy and increased frequency of senescent T cells, leading to immune compromise. However, physical activity, which influences immunity but declines dramatically with age, is not considered in this literature. We assessed immune profiles in 125 adults (55-79 years) who had maintained a high level of physical activity (cycling) for much of their adult lives, 75 age-matched older adults and 55 young adults not involved in regular exercise. The frequency of naïve T cells and recent thymic emigrants (RTE) were both higher in cyclists compared with inactive elders, and RTE frequency in cyclists was no different to young adults. Compared with their less active counterparts, the cyclists had significantly higher serum levels of the thymoprotective cytokine IL-7 and lower IL-6, which promotes thymic atrophy. Cyclists also showed additional evidence of reduced immunesenescence, namely lower Th17 polarization and higher B regulatory cell frequency than inactive elders. Physical activity did not protect against all aspects of immunesenescence: CD28 -ve CD57 +ve senescent CD8 T-cell frequency did not differ between cyclists and inactive elders. We conclude that many features of immunesenescence may be driven by reduced physical activity with age. © 2018 The Authors. Aging Cell published by the Anatomical Society and John Wiley & Sons Ltd.

  10. Chromospheric activity of periodic variable stars (including eclipsing binaries) observed in DR2 LAMOST stellar spectral survey

    Science.gov (United States)

    Zhang, Liyun; Lu, Hongpeng; Han, Xianming L.; Jiang, Linyan; Li, Zhongmu; Zhang, Yong; Hou, Yonghui; Wang, Yuefei; Cao, Zihuang

    2018-05-01

    The LAMOST spectral survey provides a rich databases for studying stellar spectroscopic properties and chromospheric activity. We cross-matched a total of 105,287 periodic variable stars from several photometric surveys and databases (CSS, LINEAR, Kepler, a recently updated eclipsing star catalogue, ASAS, NSVS, some part of SuperWASP survey, variable stars from the Tsinghua University-NAOC Transient Survey, and other objects from some new references) with four million stellar spectra published in the LAMOST data release 2 (DR2). We found 15,955 spectra for 11,469 stars (including 5398 eclipsing binaries). We calculated their equivalent widths (EWs) of their Hα, Hβ, Hγ, Hδ and Caii H lines. Using the Hα line EW, we found 447 spectra with emission above continuum for a total of 316 stars (178 eclipsing binaries). We identified 86 active stars (including 44 eclipsing binaries) with repeated LAMOST spectra. A total of 68 stars (including 34 eclipsing binaries) show chromospheric activity variability. We also found LAMOST spectra of 12 cataclysmic variables, five of which show chromospheric activity variability. We also made photometric follow-up studies of three short period targets (DY CVn, HAT-192-0001481, and LAMOST J164933.24+141255.0) using the Xinglong 60-cm telescope and the SARA 90-cm and 1-m telescopes, and obtained new BVRI CCD light curves. We analyzed these light curves and obtained orbital and starspot parameters. We detected the first flare event with a huge brightness increase of more than about 1.5 magnitudes in R filter in LAMOST J164933.24+141255.0.

  11. Abstracts of the Canadian Society for Civil Engineering annual conference including the general conference, the 1. international structural specialty conference, the 1. international construction specialty conference, and the 1. specialty conference on disaster mitigation : towards a sustainable future

    International Nuclear Information System (INIS)

    El-Badry, M.; Loov, R.E.; Ruwanpura, J.; El-Hacha, R.; Kroman, J.; Rankin, J.

    2006-01-01

    This conference provided a forum for national and international practicing engineers, researchers and technical experts to discuss sustainable solutions to infrastructure development. Discussions focused on recent developments in new technologies for building more economic and sustainable infrastructure, while improving the safety of buildings, bridges, roads, water supply and sewage treatment systems. The conference was held in conjunction with associated specialty conferences, including a first international structures specialty conference, a first international construction specialty conference, and a first specialty conference on disaster mitigation. This book of abstracts highlights all the specialty conferences and accompanies a CD-ROM that has the full text of all the papers. Manuscripts of the full papers submitted to the specialty conferences were peer-reviewed by international scientific committees. The general conference provided a forum to learn about new technologies and future directions in various areas of civil engineering. It included a special theme session on sustainable development and a special session on innovation and information technology. Other technical sessions focused on topics such as civil engineering history and education; infrastructure management and renewal; asset management; risk assessment and management; engineering materials and mechanics; environmental engineering and science; hydrotechnical engineering; cold region engineering; and, transportation engineering. The general conference featured 88 presentations, of which 15 have been catalogued separately for inclusion in this database

  12. Review of neutron activation analysis in the standardization and study of reference materials, including its application to radionuclide reference materials

    International Nuclear Information System (INIS)

    Byrne, A.R.

    1993-01-01

    Neutron activation analysis (NAA) plays a very important role in the certification of reference materials (RMs) and their characterization, including homogeneity testing. The features of the method are briefly reviewed, particularly aspects relating to its completely independent nuclear basis, its virtual freedom from blank problems, and its capacity for self-verification. This last aspect, arising from the essentially isotopic character of NAA, can be exploited by using different nuclear reactions and induced nuclides, and the possibility of employing two modes, one instrumental (nondestructive), the other radiochemical (destructive). This enables the derivation of essentially independent analytical information and the unique capacity of NAA for selfvalidation. The application of NAA to quantify natural or man-made radionuclides such as uranium, thorium, 237 Np, 129 I and 230 Th is discussed, including its advantages over conventional radiometric methods and its usefulness in providing independent data for nuclides where other confirmatory analyses are impossible, or are only recently becoming available through newer 'atom counting' techniques. Certain additional, prospective uses of NAA in the study of RMs and potential RMs are mentioned, including transmutation reactions, creation of endogenously radiolabelled matrices for production and study of RMs (such as dissolution and leaching tests, use as incorporated radiotracers for chemical recovery correction), and the possibility of molecular activation analysis for specification. (orig.)

  13. A market based active/reactive dispatch including transformer taps and reactor and capacitor banks using Simulated Annealing

    International Nuclear Information System (INIS)

    Gomes, Mario Helder; Saraiva, Joao Tome

    2009-01-01

    This paper describes an optimization model to be used by System Operators in order to validate the economic schedules obtained by Market Operators together with the injections from Bilateral Contracts. These studies will be performed off-line in the day before operation and the developed model is based on adjustment bids submitted by generators and loads and it is used by System Operators if that is necessary to enforce technical or security constraints. This model corresponds to an enhancement of an approach described in a previous paper and it now includes discrete components as transformer taps and reactor and capacitor banks. The resulting mixed integer formulation is solved using Simulated Annealing, a well known metaheuristic specially suited for combinatorial problems. Once the Simulated Annealing converges and the values of the discrete variables are fixed, the resulting non-linear continuous problem is solved using Sequential Linear Programming to get the final solution. The developed model corresponds to an AC version, it includes constraints related with the capability diagram of synchronous generators and variables allowing the computation of the active power required to balance active losses. Finally, the paper includes a Case Study based on the IEEE 118 bus system to illustrate the results that it is possible to obtain and their interest. (author)

  14. Gross Domestic Pizza. Active Learning Lessons. Economics International.

    Science.gov (United States)

    Zaleskiene, Irena; Venger, Anatoly; MacDonald, Rich; Davis, Debbie

    This lesson plan was developed through "Economics International," an international program to help build economic education infrastructures in the emerging market economies. It provides a lesson description; appropriate age level; economic concepts; content standards and benchmarks; related subject areas; instructional objectives; time…

  15. Evolution of activities in international biological standardization since the early days of the Health Organisation of the League of Nations.

    Science.gov (United States)

    Sizaret, P

    1988-01-01

    The main activities in international biological standardization during the 18 years that followed the first international biological standardization meeting in London in 1921 were concerned with expressing the potencies of test preparations in comparison with reference materials. After the Second World War, however, it became clear that the testing of biological substances against international reference materials was only one among several measures for obtaining safe and potent products. The activities in international biological standardization were therefore widened so that, by the strict observance of specific manufacturing and control requirements, it was possible to gain further in safety and efficacy. At the end of 1987, 42 international requirements for biological substances were available and were being used as national requirements, sometimes after minor modification, by the majority of WHO's Member States. This is of utmost importance for the worldwide use of safe and potent biological products, including vaccines.

  16. Orientation of sustainable management of chemical company with international activity

    Directory of Open Access Journals (Sweden)

    Valéria da Veiga Dias

    2013-04-01

    Full Text Available The search for new business possibilities, either through international activities and capture niche markets appear as a distinct trend among organizations that target growth. For this growing number of organizations intent on investing in new issues related to values such as citizenship, ethics and environmental concerns. There is the adoption of a more responsive to the community or even the acceptance of responsibility for the impacts of their production processes, inserting themselves in what was initially called the Social Responsibility within the business context and developed the concept of Elkington (1998 generated a discussion about a new movement that was called a sustainable paradigm. It was observed generally that sustainable management is still very close to supporting tools and not as part of the construction of corporate strategy although it is possible to realize that they seek a greater involvement in this direction when they start to review their strategies. This question can be perceived at different levels between the companies, but which shows the issue is the lack of direct indicators for investment and sustainable return. Sustainable management proved to be a source of opportunity for overseas business for the companies studied, as preparation for work with environmental legislation, global requirements, raw materials and environmentally friendly processes organizations prepared to market in the global sphere, and Brazil note that the innovative products for their production process and / or alternative raw material still do not get the spotlight. Acting in a sustainable manner enables the development of strategies agreed with conscious posture and changes in cultural terms in general, which can create new opportunities for those who can keep up with the global business scenario.

  17. [Geographical differences in clinical characteristics and management of stable outpatients with coronary artery disease: comparison between the Italian and international population included in the Worldwide CLARIFY registry].

    Science.gov (United States)

    Pozzoli, Massimo; Tavazzi, Luigi

    2014-04-01

    Limited data are available regarding specific differences among countries in demographic and clinical characteristics and treatment of patients with stable coronary artery disease. CLARIFY is an international, prospective and longitudinal registry including more than 33 000 patients with stable coronary artery disease enrolled in 45 countries worldwide. Data were used to compare the characteristics of patients enrolled in Italy with those enrolled in Europe and in the rest of the world. Baseline data were available for 33 283 patients, 2112 of whom from Italy and 12 614 from the remaining western European countries. Italian patients were found to be older, more frequently smoker, hypertensive and with sedentary habits. In addition, they presented more frequently a history of myocardial infarction, carotid arterial disease and chronic obstructive pulmonary disease. In addition, when compared with patients of both European and international cohorts, more Italian patients had undergone coronary angiography and angioplasty. As far as treatment was concerned, a greater number of Italian patients were taking ivabradine, angiotensin-converting enzyme inhibitors and/or angiotensin receptor blockers, nitrates, thienopyridines, while those taking beta-blockers, calcium antagonists and other antianginal medications were fewer. Among ambulatory patients with stable coronary artery disease, there are important geographic differences in terms of risk factors, clinical characteristics, surgical and pharmacological treatment.

  18. Physical activity interventions in Latin America: what value might be added by including conference abstracts in a literature review?

    Science.gov (United States)

    Hoehner, Christine; Soares, Jesus; Parra, Diana C; Ribeiro, Isabela C; Pratt, Michael; Bracco, Mario; Hallal, Pedro C; Brownson, Ross C

    2010-07-01

    This review assessed whether conference abstracts yield useful information on the types and effectiveness of community-based physical activity (PA) interventions in Latin America, beyond that from interventions included in a recent systematic review of peer-reviewed literature. Abstracts from 9 conferences were searched for community-based interventions to promote PA in Latin America and summarized. Three reviewers classified and screened abstracts. Evaluated interventions that were not included in the previous review were assessed. Search of abstracts from 31 proceedings of 9 conferences identified 87 abstracts of studies on community-based interventions focused on increasing PA. Only 31 abstracts reported on studies with a control group and an outcome related to PA. Ten of these abstracts represented interventions that had not been included in the previous review of peer-reviewed literature, but the abstracts were insufficient in number or detail to make a practice recommendation for any single intervention. This review highlighted the challenges and low added value of including conference abstracts in a systematic review of community PA interventions in Latin America. Stronger evaluation design and execution and more published reports of evaluated interventions are needed to build an evidence base supporting interventions to increase PA in Latin America.

  19. Evaluation on ultrasonic examination methods applied to Ni-base alloy weld including cracks due to stress corrosion cracking found in BWR reactor internal

    International Nuclear Information System (INIS)

    Aoki, Takayuki; Kobayashi, Hiroyuki; Higuchi, Shinichi; Shimizu, Sadato

    2005-01-01

    A Ni-base alloy weld, including cracks due to stress corrosion cracking found in the reactor internal of the oldest BWR in Japan, Tsuruga unit 1, in 1999, was examined by three (3) types of UT method. After this examination, a depth of each crack was confirmed by carrying out a little excavation with a grinder and PT examination by turns until each crack disappeared. Then, the depth measured by the former method was compared with the one measured by the latter method. In this fashion, performances of the UT methods were verified. As a result, a combination of the three types of UT method was found to meet the acceptance criteria given by ASME Sec.XI Appendix VIII, Performance Demonstration for Ultrasonic Examination Systems-Supplement 6. In this paper, the results of the UT examination described above and their evaluation are discussed. (author)

  20. Developing international alumni activities in Mikkeli University of Applied Sciences : Case Business Management degree programme

    OpenAIRE

    Honkaniemi, Meri

    2014-01-01

    My thesis focuses on international alumni activities in Mikkeli University of Applied Sciences. My aim was to find development ideas and recommendations for the international side of the alumni activities. I intended to offer realistic suggestions enough in order to make them work in practice too. I put also my effort on finding recommendations for Business Management programme, because I wanted to make sure that international alumni activities get attention in degree programme level too. ...

  1. Synergies and tensions between and within domestic and international market activities of firms

    OpenAIRE

    Karafyllia, Maria; Zucchella, Antonella

    2017-01-01

    The distinction between domestic and international market activities has an idiosyncratic meaning for international business research. This study examines the significant yet unclear role of domestic market activities for the internationalizing firm through the theoretical lens of exploitation and exploration. By means of five qualitative case studies, we show that both the dynamics between domestic-international market activities and the interplay between exploitation-exploration are intrins...

  2. Amphetamine activates Rho GTPase signaling to mediate dopamine transporter internalization and acute behavioral effects of amphetamine

    Science.gov (United States)

    Wheeler, David S.; Underhill, Suzanne M.; Stolz, Donna B.; Murdoch, Geoffrey H.; Thiels, Edda; Romero, Guillermo; Amara, Susan G.

    2015-01-01

    Acute amphetamine (AMPH) exposure elevates extracellular dopamine through a variety of mechanisms that include inhibition of dopamine reuptake, depletion of vesicular stores, and facilitation of dopamine efflux across the plasma membrane. Recent work has shown that the DAT substrate AMPH, unlike cocaine and other nontransported blockers, can also stimulate endocytosis of the plasma membrane dopamine transporter (DAT). Here, we show that when AMPH enters the cytoplasm it rapidly stimulates DAT internalization through a dynamin-dependent, clathrin-independent process. This effect, which can be observed in transfected cells, cultured dopamine neurons, and midbrain slices, is mediated by activation of the small GTPase RhoA. Inhibition of RhoA activity with C3 exotoxin or a dominant-negative RhoA blocks AMPH-induced DAT internalization. These actions depend on AMPH entry into the cell and are blocked by the DAT inhibitor cocaine. AMPH also stimulates cAMP accumulation and PKA-dependent inactivation of RhoA, thus providing a mechanism whereby PKA- and RhoA-dependent signaling pathways can interact to regulate the timing and robustness of AMPH’s effects on DAT internalization. Consistent with this model, the activation of D1/D5 receptors that couple to PKA in dopamine neurons antagonizes RhoA activation, DAT internalization, and hyperlocomotion observed in mice after AMPH treatment. These observations support the existence of an unanticipated intracellular target that mediates the effects of AMPH on RhoA and cAMP signaling and suggest new pathways to target to disrupt AMPH action. PMID:26553986

  3. VObs.it, the Italian contribution to the international Virtual Observatory-History, activities, strategy

    Science.gov (United States)

    Pasian, F.

    2015-06-01

    The origins of the Italian contribution to the international Virtual Observatory (VO) were mainly tied to the definition and implementation of a Data Grid using Grid standards. From there on, by means of a step-wise evolution, activities started including the implementation of VO-aware tools and facilities, or the production of services accessing data archives in ways compliant to the international VO standards. An important activity the Italian VO community has carried out is the dissemination of the VO capabilities to professionals, students and amateurs: in particular, an important and maybe unique success has been bringing to the classrooms the VO, and using it as a powerful tool to teach astronomy at all levels, from junior high school to undergraduate courses. Lately, there has been also direct involvement of the Italian community in the definition of standards and services within the framework of the International Virtual Observatory Alliance (IVOA), and participation and leadership in the IVOA Working Groups. Along this path, the national funding for these activities has been rather low, although essential to carry the activities on. There were no bursts of funding to allow a quick rise in activities leading to the fast realisation of tools and systems. Rather, the manpower involved in VObs.it has been always fairly low but steady. In the view of managing a national VO initiative with a low budget, strategic choices were made to exploit the available resources and to guarantee a constant background activity, mainly geared at providing services to the community, development in lower-priority VO areas, dissemination and support.

  4. The International Science and Technology Center: Scope of activities and scientific projects in the field of nuclear data

    International Nuclear Information System (INIS)

    Klepatsky, Alexander B.

    2002-01-01

    The review of the ISTC (The International Science and Technology Center) Programs and activities including Science Project Program, Partner Program, Seminar Program and others is presented. Project funding by technology area, by funding Parties, by CIS (Commonwealth of Independent States) States etc. is demonstrated with emphasis on projects in the field of nuclear data. The ISTC opportunities for international cooperation in the fields of nuclear data measurements, calculation, evaluation and dissemination are discussed. (author)

  5. Researchers active in two recent international tribology conferences

    OpenAIRE

    Nystrom, Lynn A.

    2005-01-01

    Virginia Tech faculty and former graduate students, in collaboration with researchers in Poland and Sweden, co-authored five papers presented at the international World Tribology Congress III held in Washington, D.C.

  6. ISS Internal Active Thermal Control System (IATCS) Coolant Remediation Project

    Science.gov (United States)

    Morrison, Russell H.; Holt, Mike

    2005-01-01

    The IATCS coolant has experienced a number of anomalies in the time since the US Lab was first activated on Flight 5A in February 2001. These have included: 1) a decrease in coolant pH, 2) increases in inorganic carbon, 3) a reduction in phosphate buffer concentration, 4) an increase in dissolved nickel and precipitation of nickel salts, and 5) increases in microbial concentration. These anomalies represent some risk to the system, have been implicated in some hardware failures and are suspect in others. The ISS program has conducted extensive investigations of the causes and effects of these anomalies and has developed a comprehensive program to remediate the coolant chemistry of the on-orbit system as well as provide a robust and compatible coolant solution for the hardware yet to be delivered. The remediation steps include changes in the coolant chemistry specification, development of a suite of new antimicrobial additives, and development of devices for the removal of nickel and phosphate ions from the coolant. This paper presents an overview of the anomalies, their known and suspected system effects, their causes, and the actions being taken to remediate the coolant.

  7. Internationalization as Mergers and Acquisitions: Senior International Officers' Entrepreneurial Strategies and Activities in Public Universities

    Science.gov (United States)

    Deschamps, Eric; Lee, Jenny J.

    2015-01-01

    This study investigated the various emerging forms of internationalization and how senior international affairs officers describe their motivations and rationales for implementing these activities. Based on interviews with senior international officers at 30 international offices in U.S. public universities, this study identified and classified…

  8. A Case Study of International Students' Social Adjustment, Friendship Development, and Physical Activity

    Science.gov (United States)

    Li, Shuang; Zizzi, Sam

    2018-01-01

    Previous literature has focused on international student's social transition and monocultural and bicultural ties. Little research has explored international students' multicultural friendship development and the role that physical activity plays in their social interaction. The current case study explored a group of international students'…

  9. Study protocol: Rehabilitation including Social and Physical activity and Education in Children and Teenagers with Cancer (RESPECT).

    Science.gov (United States)

    Thorsteinsson, Troels; Helms, Anne Sofie; Adamsen, Lis; Andersen, Lars Bo; Andersen, Karen Vitting; Christensen, Karl Bang; Hasle, Henrik; Heilmann, Carsten; Hejgaard, Nete; Johansen, Christoffer; Madsen, Marianne; Madsen, Svend Aage; Simovska, Venka; Strange, Birgit; Thing, Lone Friis; Wehner, Peder Skov; Schmiegelow, Kjeld; Larsen, Hanne Baekgaard

    2013-11-14

    During cancer treatment children have reduced contact with their social network of friends, and have limited participation in education, sports, and leisure activities. During and following cancer treatment, children describe school related problems, reduced physical fitness, and problems related to interaction with peers. The RESPECT study is a nationwide population-based prospective, controlled, mixed-methods intervention study looking at children aged 6-18 years newly diagnosed with cancer in eastern Denmark (n=120) and a matched control group in western Denmark (n=120). RESPECT includes Danish-speaking children diagnosed with cancer and treated at pediatric oncology units in Denmark. Primary endpoints are the level of educational achievement one year after the cessation of first-line cancer therapy, and the value of VO2max one year after the cessation of first-line cancer therapy. Secondary endpoints are quality of life measured by validated questionnaires and interviews, and physical performance. RESPECT includes a multimodal intervention program, including ambassador-facilitated educational, physical, and social interventions. The educational intervention includes an educational program aimed at the child with cancer, the child's schoolteachers and classmates, and the child's parents. Children with cancer will each have two ambassadors assigned from their class. The ambassadors visit the child with cancer at the hospital at alternating 2-week intervals and participate in the intervention program. The physical and social intervention examines the effect of early, structured, individualized, and continuous physical activity from diagnosis throughout the treatment period. The patients are tested at diagnosis, at 3 and 6 months after diagnosis, and one year after the cessation of treatment. The study is powered to quantify the impact of the combined educational, physical, and social intervention programs. RESPECT is the first population-based study to examine the

  10. DETRIMENTAL EFFECTS OF ACTIVE INTERNAL LIMITING MEMBRANE PEELING DURING EPIRETINAL MEMBRANE SURGERY: Microperimetric Analysis.

    Science.gov (United States)

    Deltour, Jean-Baptiste; Grimbert, Pierre; Masse, Helene; Lebreton, Olivier; Weber, Michel

    2017-03-01

    The aim of the study was to assess the microperimetric consequences of active internal limiting membrane (ILM) peeling during idiopathic epimacular membrane (IEMM) surgery. This retrospective monocentric study included 32 eyes of 31 consecutive patients who underwent IEMM surgery. Internal limiting membrane integrity was assessed by ILM Blue staining after IEMM removal: peeling was spontaneous (Group S) or active (Group A). Preprocedure and postprocedure (1 and 6 months) examinations were performed using visual acuity determination, spectral domain optical coherence tomography and microperimetry. Twenty-two eyes had an "active ILM peeling" and 10 a "spontaneous ILM peeling." Both groups had comparable and significant improvements in visual acuity 6 months after surgery (+1.82 lines [+9 letters] [Group A] and +1.51 lines [+8 letters] [Group S], P peeling has progressively become generalized in IEMM surgery to reduce recurrences. This additional procedure does not change the postoperative visual acuity but increases the development of deeper microscotomas. The real impact on the quality of vision remains unclear. Active ILM peeling in IEMM surgery may be responsible for visual impairment related to its microtraumatic effects.

  11. Factors Affecting the Internal Audit Effectiveness

    OpenAIRE

    Mustika, Adhista Cahya

    2015-01-01

    This study tests the factors that influence the internal audit effectiveness, including internal auditor competencies, internal auditor independence, auditee support to internal audit activity, and the internal and external auditor relationship. Using the internal auditor inspectorate in Java Province, Indonesia, we found that the internal audit effectiveness can be attained through increase internal audit competence, independence and strong relationship between internal and external auditor....

  12. The descriptive epidemiology of sitting. A 20-country comparison using the International Physical Activity Questionnaire (IPAQ).

    Science.gov (United States)

    Bauman, Adrian; Ainsworth, Barbara E; Sallis, James F; Hagströmer, Maria; Craig, Cora L; Bull, Fiona C; Pratt, Michael; Venugopal, Kamalesh; Chau, Josephine; Sjöström, Michael

    2011-08-01

    Recent epidemiologic evidence points to the health risks of prolonged sitting, that are independent of physical activity, but few papers have reported the descriptive epidemiology of sitting in population studies with adults. This paper reports the prevalence of "high sitting time" and its correlates in an international study in 20 countries. Representative population samples from 20 countries were collected 2002-2004, and a question was asked on usual weekday hours spent sitting. This question was part of the International Prevalence Study, using the International Physical Activity Questionnaire (IPAQ). The sitting measure has acceptable reliability and validity. Daily sitting time was compared among countries, and by age group, gender, educational attainment, and physical activity. Data were available for 49,493 adults aged 18-65 years from 20 countries. The median reported sitting time was 300 minutes/day, with an interquartile range of 180-480 minutes. Countries reporting the lowest amount of sitting included Portugal, Brazil, and Colombia (medians ≤180 min/day), whereas adults in Taiwan, Norway, Hong Kong, Saudi Arabia, and Japan reported the highest sitting times (medians ≥360 min/day). In adjusted analyses, adults aged 40-65 years were significantly less likely to be in the highest quintile for sitting than adults aged 18-39 years (AOR=0.796), and those with postschool education had higher sitting times compared with those with high school or less education (OR=1.349). Physical activity showed an inverse relationship, with those reporting low activity on the IPAQ three times more likely to be in the highest-sitting quintile compared to those reporting high physical activity. Median sitting time varied widely across countries. Assessing sitting time is an important new area for preventive medicine, in addition to assessing physical activity and sedentary behaviors. Population surveys that monitor lifestyle behaviors should add measures of sitting time to

  13. A novel synthetic quantification standard including virus and internal report targets: application for the detection and quantification of emerging begomoviruses on tomato.

    Science.gov (United States)

    Péréfarres, Frédéric; Hoareau, Murielle; Chiroleu, Frédéric; Reynaud, Bernard; Dintinger, Jacques; Lett, Jean-Michel

    2011-08-05

    Begomovirus is a genus of phytopathogenic single-stranded DNA viruses, transmitted by the whitefly Bemisia tabaci. This genus includes emerging and economically significant viruses such as those associated with Tomato Yellow Leaf Curl Disease, for which diagnostic tools are needed to prevent dispersion and new introductions. Five real-time PCRs with an internal tomato reporter gene were developed for accurate detection and quantification of monopartite begomoviruses, including two strains of the Tomato yellow leaf curl virus (TYLCV; Mld and IL strains), the Tomato leaf curl Comoros virus-like viruses (ToLCKMV-like viruses) and the two molecules of the bipartite Potato yellow mosaic virus. These diagnostic tools have a unique standard quantification, comprising the targeted viral and internal report amplicons. These duplex real-time PCRs were applied to artificially inoculated plants to monitor and compare their viral development. Real-time PCRs were optimized for accurate detection and quantification over a range of 2 × 10(9) to 2 × 10(3) copies of genomic viral DNA/μL for TYLCV-Mld, TYLCV-IL and PYMV-B and 2 × 10(8) to 2 × 10(3) copies of genomic viral DNA/μL for PYMV-A and ToLCKMV-like viruses. These real-time PCRs were applied to artificially inoculated plants and viral loads were compared at 10, 20 and 30 days post-inoculation. Different patterns of viral accumulation were observed between the bipartite and the monopartite begomoviruses. Interestingly, PYMV accumulated more viral DNA at each date for both genomic components compared to all the monopartite viruses. Also, PYMV reached its highest viral load at 10 dpi contrary to the other viruses (20 dpi). The accumulation kinetics of the two strains of emergent TYLCV differed from the ToLCKMV-like viruses in the higher quantities of viral DNA produced in the early phase of the infection and in the shorter time to reach this peak viral load. To detect and quantify a wide range of begomoviruses, five duplex

  14. A novel synthetic quantification standard including virus and internal report targets: application for the detection and quantification of emerging begomoviruses on tomato

    Directory of Open Access Journals (Sweden)

    Lett Jean-Michel

    2011-08-01

    Full Text Available Abstract Background Begomovirus is a genus of phytopathogenic single-stranded DNA viruses, transmitted by the whitefly Bemisia tabaci. This genus includes emerging and economically significant viruses such as those associated with Tomato Yellow Leaf Curl Disease, for which diagnostic tools are needed to prevent dispersion and new introductions. Five real-time PCRs with an internal tomato reporter gene were developed for accurate detection and quantification of monopartite begomoviruses, including two strains of the Tomato yellow leaf curl virus (TYLCV; Mld and IL strains, the Tomato leaf curl Comoros virus-like viruses (ToLCKMV-like viruses and the two molecules of the bipartite Potato yellow mosaic virus. These diagnostic tools have a unique standard quantification, comprising the targeted viral and internal report amplicons. These duplex real-time PCRs were applied to artificially inoculated plants to monitor and compare their viral development. Results Real-time PCRs were optimized for accurate detection and quantification over a range of 2 × 109 to 2 × 103 copies of genomic viral DNA/μL for TYLCV-Mld, TYLCV-IL and PYMV-B and 2 × 108 to 2 × 103 copies of genomic viral DNA/μL for PYMV-A and ToLCKMV-like viruses. These real-time PCRs were applied to artificially inoculated plants and viral loads were compared at 10, 20 and 30 days post-inoculation. Different patterns of viral accumulation were observed between the bipartite and the monopartite begomoviruses. Interestingly, PYMV accumulated more viral DNA at each date for both genomic components compared to all the monopartite viruses. Also, PYMV reached its highest viral load at 10 dpi contrary to the other viruses (20 dpi. The accumulation kinetics of the two strains of emergent TYLCV differed from the ToLCKMV-like viruses in the higher quantities of viral DNA produced in the early phase of the infection and in the shorter time to reach this peak viral load. Conclusions To detect and

  15. 14 CFR 1213.109 - News releases concerning international activities.

    Science.gov (United States)

    2010-01-01

    ... Headquarters offices of External Relations and Public Affairs. (b) NASA Centers and Headquarters offices will report all visits proposed by representatives of foreign news media to the Public Affairs Officer of the... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false News releases concerning international...

  16. Evolution of deceased organ donation activity vs. efficiency over a 15 year period: an international comparison.

    Science.gov (United States)

    Weiss, Julius; Elmer, Andreas; Mahíllo, Beatriz; Domínguez-Gil, Beatriz; Avsec, Danica; Costa, Alessandro Nanni; Haase-Kromwijk, Bernadette J J M; Laouabdia, Karim; Immer, Franz F

    2018-04-19

    The donation rate (DR) per million population is not ideal for an efficiency comparison of national deceased organ donation programs. The DR does not account for variabilities in the potential for deceased donation which mainly depends on fatalities from causes leading to brain death. In this study, the donation activity was put into relation to the mortality from selected causes. Based on that metric, this study assesses the efficiency of different donation programs. This is a retrospective analysis of 2001-2015 deceased organ donation and mortality registry data. Included are 27 Council of Europe countries, as well as the USA. A donor conversion index (DCI) was calculated for assessing donation program efficiency over time and in international comparisons. According to the DCI and of the countries included in the study, Spain, France, and the USA had the most efficient donation programs in 2015. Even though mortality from the selected causes decreased in most countries during the study period, differences in international comparisons persist. This indicates that the potential for deceased organ donation and its conversion into actual donation is far from being similar internationally. Compared with the DR, the DCI takes into account the potential for deceased organ donation, and therefore is a more accurate metric of performance. National donation programs could optimize performance by identifying the areas where most potential is lost, and by implementing measures to tackle these issues.

  17. Institutional factor in international economic activity of region and its socio-economic development

    Directory of Open Access Journals (Sweden)

    Elena Leonidovna Andreeva

    2016-12-01

    Full Text Available The article substantiates the impact of the institutional factor on the development of regional international economic relations. The scope of the study is regional international economic activity (IEA, the subject-matter is the role of the institutional factor in its development. The study purpose is to develop a scientific approach for the assessment of the institutional factor impact on the development of region’s international economic relations. The hypothesis is that the targeted efforts of all participants of IEA of the region (business, authorities, local community to strengthen of theese components of the institutional factor, which have a strong influence on the regional socio-economic development. A methodological approach for the assessment of this influenceis developed. It includes determining three elements of IEA institutionalization—agreements, organizations, events. A three-dimensional model is proposed for the coordination of these elements with 3 groups of countries—developed, developing and CIS, including the Eurasian Economic Union, and also with basic indexes characterizing the qualitative and quantitative contribution of region’s IEA into its socio-economic development. This model is tested on the example of the Sverdlovsk region of Russia for 2003–2015. That has allowed to define various kinds of the effects from strenthening the IEA institutional component, which are expressed in the increase of the export of the region, improvement of its investment attractiveness, the diversification of regional economy as well as the the generation of additional jobs and tax flows increase.

  18. 42 CFR 460.136 - Internal quality assessment and performance improvement activities.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Internal quality assessment and performance improvement activities. 460.136 Section 460.136 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES....136 Internal quality assessment and performance improvement activities. (a) Quality assessment and...

  19. International Thermonuclear Experimental Reactor (ITER). Engineering Design Activities (EDA). Agreement and protocol 1

    International Nuclear Information System (INIS)

    1992-01-01

    This document contains protocol 1 to the agreement among the European Atomic Energy Community, the government of Japan, the Government of the Russian Federation, and the Government of the United States of America on cooperation in the engineering design activities for the International Thermonuclear Experimental Reactor, which activities shall be conducted under the auspices of the International Atomic Energy Agency

  20. Intercultural Competence in the Context of Youth Non-Governmental Organisations’ International Activities

    OpenAIRE

    Alvydė Palaimaitė; Asta Radzevičienė

    2011-01-01

    Increasingly growing necessity for international cooperation of Lithuanian youth non-governmental organization is analyzed in the article. The appropriateness of intercultural competence development for enhancing international activities of Youth non-governmental organization is examined. The results of empirical survey, which confirm the hypothesis that the lack of intercultural competence is the main barrier for international cooperation activities of youth non-governmental organizations, a...

  1. Water quality - Determination of tritium activity concentration - Liquid scintillation counting method (International Standard Publication ISO 9698:1989)

    International Nuclear Information System (INIS)

    Stefanik, J.

    1999-01-01

    This International Standard specifies a method for the determination of tritiated water ([ 3 H]H 2 O) activity concentration in water by liquid scintillation counting. The method is applicable to all types of water including seawater with tritium activity concentrations of up to 10 6 Bq/m 3 when using 20 ml counting vials. Below tritium activity concentrations of about 5 x 10 4 Bq/m 3[ 8], a prior enrichment step and/or the measurement of larger sample volumes can significantly improve the accuracy of the determination and lower the limit of detection. Tritium activity concentrations higher than 10 6 Bq/m 3 may be determined after appropriate dilution with distilled water of proven low tritium content. An alternative method for the determination of these higher activities involves increasing the tritium activity concentrations of the internal standard solution. The method is not applicable to the analysis of organically bound tritium; its determination requires an oxidative digestion

  2. Enhancing International Research and Development-Project Activity on University Campuses: Insights from U.S. Senior International Officers

    Science.gov (United States)

    Koehn, Peter H.; Deardorff, Darla K.; Bolognese, Kerry D.

    2011-01-01

    In the interconnected world of the UN Decade of Education for Sustainable Development, the ability of higher-education institutions to contribute to and benefit from international research undertakings, sustainable-development-project activity, and capacity-building endeavors requires transnational involvement. While the potential benefits are…

  3. 7th international conference ''Modern trends in activation analysis''

    International Nuclear Information System (INIS)

    Obrusnik, I.

    1987-01-01

    The conference was held on 23-27 June, 1986 in Copenhagen (DK) with the participation of specialists from 42 countries. 175 papers were submitted covering the wide field of applications of neutron activation analysis, from novel techniques to sample preparation, information processes and control, activation techniques, light element and rare earth element determination, ultratracer analysis, quality assurance, comparator methods, and reference materials. The poster session was mainly oriented to industrial applications of activation analysis, biological applications, in vivo use of neutron activation analysis, the applications of neutron activation analysis in environmental control, criminology, etc. (E.S.)

  4. Development of a comprehensive survey of sexuality issues including a self-report version of the International Spinal Cord Injury sexual function basic data sets.

    Science.gov (United States)

    New, P W; Currie, K E

    2016-08-01

    Questionnaire development, validation and completion. Develop comprehensive survey of sexuality issues including validated self-report versions of the International Spinal Cord Injury male sexual function and female sexual and reproductive function basic data sets (SR-iSCI-sexual function). People with spinal cord damage (SCD) living in the community, Australia from August 2013 to June 2014. An iterative process involving rehabilitation medicine clinicians, a nurse specialising in sexuality issues in SCD and people with SCD who developed a comprehensive survey that included the SR-iSCI-sexual function. Participants recruitment through spinal rehabilitation review clinic and community organisations that support people with SCD. Surveys completed by 154 people. Most were male (n=101, 65.6%). Respondents' median age was 50 years (interquartile range (IQR) 38-58), and they were a median of 10 years (IQR 4-20) after the onset of SCD. Sexual problems unrelated to SCD were reported by 12 (8%) respondents, and 114 (n=75.5%) reported sexual problems because of SCD. Orgasms were much less likely (χ(2)=13.1, P=0.006) to be normal in males (n=5, 5%) compared with females (n=11, 22%). Males had significantly worse (χ(2)=26.0, P=0.001) psychogenic genital functioning (normal n=9, 9%) than females (normal n=13, 26%) and worse (χ(2)=10.8, P=0.013) reflex genital functioning. Normal ejaculation was reported in only three (3%) men. Most (n=26, 52%) women reported reduced or absent menstruation pattern since SCD. The SR-iSCI-sexual function provides a useful tool for researchers and clinicians to collect information regarding patient-reported sexual functioning after SCD and to facilitate comparative studies.

  5. The international ISOE programme. ISOE European technical centre activities

    International Nuclear Information System (INIS)

    Ascenzo, L. d'; Crouail, P.; Levy, F.; Livolsi, P.; Schieber, C.; Lefaure, C.

    1996-01-01

    The CEPN has been involved from the beginning in the NEA Information System on Occupational Exposure (ISOE). As ISOE European Technical Centre, the CEPN is responsible for the collection and distribution of European data to the various ISOE partners, the collection of data from the other regional technical centres, and the custodianship of the full ISOE data base. This full data base is updated annually and distributed to all the European participating utilities and to other Regional Technical Centres. The European data are also sent to the European Commission (EC) as a contribution to their own occupational exposure data base. In addition to these activities, the CEPN has developed two computer programmes under Windows to facilitate the management of ISOE data bases. The first software, called ASPIC, allows participating utilities to electronically complete NEA1 and NEA3 questionnaires, as well as to consult the NEA3 data base using key words search routine. This software is available in six different languages. The second programme is a relational data base for the performance of statistical analyses using data from NEA1. The CEPN also contributes significantly to the efficient flow of information through the ISOE Network. This includes participation in the preparation and distribution of the ISOE Annual Report (which presents and analyses NEAI data), ISOE Information Sheets (providing short synthesis using NEA1 and NEA3 data), and Technical Reports. Participating Authorities and Utilities have each made information requests to the CEPN concerning dosimetric data, radiation protection experiences, policies and practices. Some examples of these requests, and of the types of data provided, will be presented. (author)

  6. The activity of the international cooperation of BIOMOVS I

    International Nuclear Information System (INIS)

    Kanyar, B.

    1993-01-01

    The Biospheric Model Validation Study (BIOMOVS) is an international cooperation study on testing of models to predict the distribution and accumulation of radioactive and other toxic substances in the biosphere. The main objectives of the study are to compare and test the predictions, recommend priorities for future development concerning the improvement of the models. The international cooperation initiated in 1985 by the Swedish National Institute of Radiation Protection (NIRP), Stockholm is involved in two kinds of approaches. Approach A means to test model predictions against independent sets of real data. Approach B, on the other hand, aims to compare model predictions obtained from the different models for specific test scenarios. The first phase of the BIOMOVS lasted until 1990, the BIOMOVS II should begin in 1991

  7. China’s International Behavior. Activism, Opportunism, and Diversification

    Science.gov (United States)

    2009-01-01

    assessments of their national goals, see Yan Xuetong, Guoji Zhengzhi yu Zhong - guo [International Politics and China], Beijing , China: Beijing Daxue ...Decisions: Important State Strategies After 1989], Beijing , China: Zhong - yang Dangli Chubanshe, 2004, pp. 783–806. 11 Swaine and Tellis, 2000, pp. 1–20...at the Conference on East Asian Security, Beijing , China, December 15, 2003; and Wang Yi, “Quanqiuhua Jincheng Zhong de Yazhou Quyu Hezuo” [Asian

  8. Antimicrobial Active Packaging including Chitosan Films with Thymus vulgaris L. Essential Oil for Ready-to-Eat Meat

    Directory of Open Access Journals (Sweden)

    Jesús Quesada

    2016-08-01

    Full Text Available An active packaging system has been designed for the shelf life extension of ready to eat meat products. The package included an inner surface coated with a chitosan film with thyme essential oil (0%, 0.5%, 1%, and 2% not in direct contact with the meat. Our aim was to reduce the impact of thyme essential oil (EO on meat sensory properties by using a chemotype with low odor intensity. The pH, color parameters, microbial populations, and sensory properties were assessed during 4 weeks of refrigerated storage. The presence of EO films reduced yeast populations, whereas aerobic mesophilic bacteria, lactic acid bacteria, and enterobacteria were not affected by the presence of the EO in the films. Meat color preservation (a * was enhanced in the presence of EO, giving a better appearance to the packaged meat. The presence of the chitosan-EO layer reduced water condensation inside the package, whereas packages containing only chitosan had evident water droplets. Thyme odor was perceived as desirable in cooked meat, and the typical product odor intensity decreased by increasing the EO concentration. Further studies should point towards developing oil blends or combinations with natural antimicrobial agents to be incorporated into the film to improve its antimicrobial properties.

  9. A single parameter representation of hygroscopic growth and cloud condensation nucleus activity – Part 2: Including solubility

    Directory of Open Access Journals (Sweden)

    M. D. Petters

    2008-10-01

    Full Text Available The ability of a particle to serve as a cloud condensation nucleus in the atmosphere is determined by its size, hygroscopicity and its solubility in water. Usually size and hygroscopicity alone are sufficient to predict CCN activity. Single parameter representations for hygroscopicity have been shown to successfully model complex, multicomponent particles types. Under the assumption of either complete solubility, or complete insolubility of a component, it is not necessary to explicitly include that component's solubility into the single parameter framework. This is not the case if sparingly soluble materials are present. In this work we explicitly account for solubility by modifying the single parameter equations. We demonstrate that sensitivity to the actual value of solubility emerges only in the regime of 2×10−1–5×10−4, where the solubility values are expressed as volume of solute per unit volume of water present in a saturated solution. Compounds that do not fall inside this sparingly soluble envelope can be adequately modeled assuming they are either infinitely soluble in water or completely insoluble.

  10. International Atomic Energy Agency highlights of activities. 1995

    International Nuclear Information System (INIS)

    1995-09-01

    The IAEA activities are outlined in the following areas: nuclear power, nuclear fuel cycle, radioactive waste management, comparative assessment of energy sources, IAEA laboratories, research and technical cooperation, food and agriculture, human health, industry and earth sciences, physical and chemical sciences, safety of nuclear installations, radiation protection, safeguards and non-proliferation activities, public and technical information

  11. Annual report 34-37 on the activities of the Institute for International Law of the University of Goettingen

    International Nuclear Information System (INIS)

    1986-01-01

    The report reviews the scientific activities of the institute from 1982 to 1985. The Department for Atomic Energy Law continued with research and documentation dealing with all legal questions concerning the peaceful use of nuclear energy and the protection against ionising radiation, including international law agreements and the safeguards system. The subjects of all seminars held are listed, the theses and other publications, and also other scientific activities outside the institute. (HSCH) [de

  12. Managing Nuclear Knowledge: IAEA Activities and International Coordination. Asian Network for Education in Nuclear Technology (ANENT)

    International Nuclear Information System (INIS)

    2007-07-01

    The important role which the International Atomic Energy Agency (IAEA) plays in assisting Member States in the preservation and enhancement of nuclear knowledge and in facilitating international collaboration in this area has been recognized by the General Conference of the International Atomic Energy Agency in resolutions GC(46)/RES/11B, GC(47)/RES/10B, GC(48)/RES/13 and GC(50)/RES/13. The IAEA continues to support the enhancement and stabilization of nuclear education and training with the objective of securing the availability of qualified human resources for the nuclear sector. Its most important approaches are networking regional educational institutions and fostering cooperation to develop harmonized curricula, prepare and disseminate teaching materials. The Asian Network for Education in Nuclear Technology (ANENT), established by the IAEA in 2004, became operational in 2005. An ANENT website has been set up and is being expanded, such as developing a long-distance learning platform. Also, a reference curriculum for nuclear engineering is being developed with the cooperation of external partners.This booklet summarizes the main activities being carried out by the IAEA with regard to the Asian Network for Education in Nuclear Technology (ANENT) and other related activities including those completed during the period 2002–2005. It briefly describes the background information on the events leading to the formation of the ANENT; the terms of reference formulated at the second Coordination Committee meeting held in Vietnam, October 2005; and objectives, strategy and other institutional and managerial policies reaffirmed by the members. CD-ROM attached to the printed booklet containing nearly all of the background material in full text, including policy level papers, reports, presentations made by Member States, and meeting summaries

  13. Internal quality control of neutron activation analysis laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Kim, S. H.; Mun, J. H.; BaeK, S. Y.; Jung, Y. S.; Kim, Y. J. [KAERI, Taejon (Korea, Republic of)

    2004-07-01

    The importance for quality assurance and control in analytical laboratories has been emphasized, day by day. Internal quality control using certified reference materials(CRMs) can be one of effective methods for this purpose. In this study, 10 kinds of CRMs consisting of soil, sediment and biological matrix were analyzed. To evaluate the confidence of analytical results and the validation of testing method and procedure, the accuracy and the precision of the measured elements were treated statistically and the reproducibility was compared with those values produced before 2003.

  14. True dose from incorporated activities. Models for internal dosimetry

    International Nuclear Information System (INIS)

    Breustedt, B.; Eschner, W.; Nosske, D.

    2012-01-01

    The assessment of doses after incorporation of radionuclides cannot use direct measurements of the doses, as for example dosimetry in external radiation fields. The only observables are activities in the body or in excretions. Models are used to calculate the doses based on the measured activities. The incorporated activities and the resulting doses can vary by more than seven orders of magnitude between occupational and medical exposures. Nevertheless the models and calculations applied in both cases are similar. Since the models for the different applications have been developed independently by ICRP and MIRD different terminologies have been used. A unified terminology is being developed. (orig.)

  15. International Comparability of 131I, 201TI and 99mTc Activity Measurements performed in Cuban Nuclear Medicine

    International Nuclear Information System (INIS)

    Oropesa, P; Serra, R; Hernandez, A.T.; Varela, C

    2006-01-01

    This paper refers about the International Comparability of 131 I, 201 TI and 99m Tc Activity Measurements performed in Cuban Nuclear Medicine. Traceability of activity measurements in nuclear medicine based in two aspects: Comparability of clinic results and the safe and effective use of drugs. A bilateral international comparison for activity measurements CIEMAT CENTIS DMR was done. 2000-2004 National Program for 99m Tc 201 TI, 131 I vial and syringe measurements in radionuclide calibrators including a simulated test for activity administration. It is employed the Cause Effect Diagram for the activity measurement result of a source in the calibrator and the statistical methods for comparing several characteristics of the obtained data. The result of the comparisons demonstrates that the measurement quality has increased from one year to another

  16. International cooperation in the safety and environmental assessment for the ITER engineering design activities

    International Nuclear Information System (INIS)

    Gordon, C.; Baker, D.J.; Bartels, H-W.

    1998-01-01

    The ITER Project includes design and assessment activities to ensure the safety and environmental attractiveness of ITER and demonstrate that it can be sited in any of the sponsoring Parties with a minimum of site-specific redesign. This paper highlights some of the efforts to develop an international consensus approach for ITER safety design and assessment, including: development of general safety and environmental design criteria; development of quantitative dose-release assessment criteria; development of a radiation protection program; waste characterization; and development of safety analysis guidelines. The high level of interaction, cooperation and collaboration between the Joint Central Team and the Home Teams, and between the safety team and designers, and the spirit of consensus that has guided them have resulted in a safe design for ITER and a safety design and assessment that can meet the needs of the potential host countries. (author)

  17. Use of the international systemic scleroderma activity index

    Directory of Open Access Journals (Sweden)

    Maya Nikolayevna Starovoitova

    2013-01-01

    Full Text Available Up to now, it is difficult to determine systemic scleroderma (SSD activity because of the lack of validated tools to estimate changes in the pathological process. Attempts have been made to develop unified activity assessing methods for many years. The indices proposed by the European SSD Group are most popular today. This paper gives the results of using this index in a cohort of Russian patients.

  18. The aims and activities of the International Network of Nuclear Structure and Decay Data Evaluators

    International Nuclear Information System (INIS)

    Nichols, A.L.; Tuli, J.K.

    2008-01-01

    The International Network of Nuclear Structure and Decay Data (NSDD) experts consists of a number of evaluation groups and data service centres in several countries that appreciate the merits of working together to maintain and ensure the quality and comprehensive content of the ENSDF database (Evaluated Nuclear Structure Data File). Biennial meetings of the network are held under the auspices of the International Atomic Energy Agency (IAEA) to assign evaluation responsibilities, monitor progress, discuss improvements and emerging difficulties, and agree on actions to be undertaken by individual members. The evaluated data and bibliographic details are made available to users via various media, such as the journals Nuclear Physics A and Nuclear Data Sheets, the World Wide Web, on CD-Rom, wall charts of the nuclides and Nuclear Wallet Cards. While the ENSDF master database is maintained by the US National Nuclear Data Center at the Brookhaven National Laboratory, these data are also available from other nuclear data centres including the IAEA Nuclear Data Section. The Abdus Salam International Centre for Theoretical Physics (ICTP), Trieste, Italy, in cooperation with the IAEA, organizes workshops on NSDD at regular intervals. The primary aims of these particular workshops are to provide hands-on training in the data evaluation processes, and to encourage new experts to participate in NSDD activities. The technical contents of these NSDD workshops are described, along with the rationale for the inclusion of various topics. (authors)

  19. International medallists' and non-medallists' developmental sport activities - a matched-pairs analysis.

    Science.gov (United States)

    Güllich, Arne

    2017-12-01

    The study examined developmental participation patterns of international top athletes. Pairs of 83 international medallists (including 38 Olympic/World Champions) and 83 non-medallists were matched by sport, age and gender. A questionnaire recorded their volume of organised (coach-led) practice/training in their respective main sport and in other sports through childhood, adolescence and adulthood, and also involvement in non-organised (peer-led) sport activity. Analyses revealed that the medallists started practice/training in their main sport at an older age than non-medallists and accumulated slightly, but significantly less main-sport practice/training through childhood/adolescence. But they participated in more practice/training in other sports, particularly before entering their main sport. The medallists also maintained engagement in other sports over more years and specialised later than the non-medallists. Other sports engaged in were mostly unrelated to an athlete's main sport. The results were robust across different types of sports. The observations are reflected against tenets of the "deliberate practice" and "Developmental Model of Sport Participation" frameworks. Early diversified practice and learning experiences are discussed relative to the expansion of youngsters' potential for future long-term learning. In elite athletes, interaction of sport-specific practice/training with early other-sports participation mostly facilitates long-term attainment of international senior medals.

  20. The Black Sea one decade after the Bucharest Convention an overview of the international activities in the Black Sea region

    International Nuclear Information System (INIS)

    Goektepe, G.

    2002-01-01

    The catastrophic degradation of the Black Sea in a period of four decade has been the major concern of the Black Sea countries and international communities since Bucharest Convention signed in 1992. The Black Sea Region has became a challenging international arena for political scientific and socio-economic activities. Intensive international programmes and establishment of governmental and Non Governmental Organizational structures of the 1990s including Black Sea Economic Cooperation (BSEC), Black Sea Environmental Programme(BSEP), Environmental Programme for the Danube River Basin, Marine Environmental Assessment of the Black Sea Region Technical Cooperation Programme by the IAEA and establishment of the Black Sea Commission Permanent Secretariat are some of the major international efforts of the past decade that emphasizes the multi-nationality and large dimension of the Black Sea environmental management issues. The environmental degradation of the Black Sea is briefly reviewed based on the BSEP reports and data available for land based pollution sources. The environmental risk of marine vessel accidents are indicated and environmental safety concern is emphasized under the current conditions of intense energy transportation projects in the Black Sea and Caspian regions. The international policy actions, co-operation issues and scientific programmes of the past decade are overviewed with emphasis on the international achievements. Concluding remarks include the vital importance of continuation of the international commitments and sharing the political, scientific and socio-economic responsibility on the transboundary environmental pollution, rehabilitation and the safety issues of the Black Sea

  1. 25 CFR 170.137 - What types of activities can a recreation, tourism, and trails program include?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What types of activities can a recreation, tourism, and... Eligibility Recreation, Tourism and Trails § 170.137 What types of activities can a recreation, tourism, and... may perform under a recreation, tourism, and trails program: (1) Transportation planning for tourism...

  2. A particular articulation of judicial activism of the CJEU in its approach towards international law

    DEFF Research Database (Denmark)

    Cebulak, Pola

    2012-01-01

    This paper seeks to provide a theoretical and methodological framework that can be used in assessing the judicial activism of the Court of Justice of the European Union (CJEU) in its jurisprudence dealing with public international law. The underlying questions are: What underpins the judicial...... activism of the EU judge in the jurisprudence concerning the relationship between European and public international law? How does the EU judge’s approach to international law shape the relationship between the two legal orders? The chapter proposes the hypothesis that judicial activism and a pluralistic...

  3. International Atomic Energy Agency. Highlights of activities. September 1994

    International Nuclear Information System (INIS)

    Gillen, V.A.

    1994-09-01

    The document presents the main activities of the IAEA between September 1993-September 1994 in the following fields: Nuclear power, Nuclear fuel cycle, Radioactive waste management, Comparative assessment of energy sources, IAEA laboratories, Food and agriculture, Human health, Industry and earth sciences, Radiation protection, Safety of nuclear installations, Safeguards and non-proliferation activities, Public and technical information, Research and technical co-operation. There are also given information about IAEA secretariat, organization and administration, the 1993 IAEA General Conference, IAEA Member States and IAEA Network

  4. Anthelminthic activity of Asta Churna | Devi | International Journal of ...

    African Journals Online (AJOL)

    Purpose: To determine the effect of Asta churna (an ayurvedic preparation of Impcops) on Indian earthworms. Methods: Asta churna (2.5 mg/mL and 5 mg/mL) were investigated for activity in Indian earthworms (Pheretima postuma) against piperazine citrate (15 mg/mL) and albendazole (20 mg/mL) as standard references ...

  5. International Centre for Theoretical Physics, Trieste: Scientific activities in 1988

    International Nuclear Information System (INIS)

    1989-10-01

    The document contains three parts. Part I is a review of the Scientific activities in 1988 with a statistical digest. Part II describes the scientific programme in Fundamental physics, Condensed matter, Atomic and molecular physics, Mathematics, Physics and energy, Physics and environment, Physics of the living state, Applied physics, Adriatico research conferences. Part III lists the publications issued in 1988. Tabs

  6. In vitro activity of the siderophore monosulfactam BAL30072 against contemporary Gram-negative pathogens from New York City, including multidrug-resistant isolates.

    Science.gov (United States)

    Landman, David; Singh, Manisha; El-Imad, Badiaa; Miller, Ezra; Win, Thida; Quale, John

    2014-06-01

    The in vitro activity of BAL30072 was assessed against clinical isolates from NYC hospitals, including isolates from a citywide surveillance study and a collection of isolates with well-characterised resistance mechanisms. BAL30072 was the most active β-lactam against Pseudomonas aeruginosa (MIC50/90, 0.25/1 μg/mL), Acinetobacter baumannii (MIC50/90, 4/>64 μg/mL) and KPC-possessing Klebsiella pneumoniae (MIC50/90, 4/>64 μg/mL). Combining BAL30072 with meropenem resulted in a ≥ 4-fold decrease in the BAL30072 MIC90 both for A. baumannii and K. pneumoniae. For isolates with a BAL30072 MIC>4 μg/mL, addition of a sub-MIC concentration of colistin resulted in a four-fold decrease in the BAL30072 MIC in 44% of P. aeruginosa, 82% of A. baumannii and 23% of K. pneumoniae. Using sub-MIC concentrations, BAL30072 plus colistin was bactericidal against 4 of 11 isolates in time-kill studies. BAL30072 MICs were frequently lower for P. aeruginosa and K. pneumoniae when tested using Mueller-Hinton agar versus Iso-Sensitest agar or Mueller-Hinton broth. Against the well-characterised isolates, reduced susceptibility to BAL30072 correlated with mexA and mexX expression (P. aeruginosa), adeB expression (A. baumannii) and presence of SHV-type ESBLs (A. baumannii and K. pneumoniae). BAL30072 shows promising activity against contemporary Gram-negatives, including MDR P. aeruginosa, A. baumannii and K. pneumoniae. Enhanced activity was often present when BAL30072 was combined with meropenem or colistin. BAL30072 MICs were influenced by the testing method, particularly for P. aeruginosa and K. pneumoniae. Further in vivo studies are warranted to determine the potential clinical utility of BAL30072 alone and combined with other agents. Copyright © 2014 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.

  7. Organizational structure and basic functions of international convention «SportAссord» activity

    Directory of Open Access Journals (Sweden)

    Nina Dolbysheva

    2015-06-01

    Full Text Available Purpose: to define and determine the basic functions of International convention “SportAссord” activity within the framework of international sport movement. Materials and Methods: 21 literary sources have been analyzed. Results: International convention “SportAссord” is a nongovernmental sport organization, which unites, supports, coordinates and protects international sport federations and organizations in the international sport movement. “SportAссord” does its activities in accordance with United Nations General Assembly Resolution 1296 (XLIV, provisions of the International Olympic Charter and Code of Ethics, grounding on World Anti-Doping Code. The president is the head of administrative office, with the departments and board of executive body under control. General Assembly is the supreme authority, which carries out the range of basic tasks and grants authority to the management of “SportAccord” and its members for them to fulfill general and special functions. Conclusions: the International convention “SportAccord” activity is aimed at carrying out tasks by fulfilling general and special functions on the basis of international and internal legal documents.

  8. Non-Exercise Estimation of VO[subscript 2]max Using the International Physical Activity Questionnaire

    Science.gov (United States)

    Schembre, Susan M.; Riebe, Deborah A.

    2011-01-01

    Non-exercise equations developed from self-reported physical activity can estimate maximal oxygen uptake (VO[subscript 2]max) as well as sub-maximal exercise testing. The International Physical Activity Questionnaire is the most widely used and validated self-report measure of physical activity. This study aimed to develop and test a VO[subscript…

  9. Absolute determination of 75Se for international comparison of activity measurements

    International Nuclear Information System (INIS)

    Iglicki, F.A.; Arenillas, P.A.; Furnari, J.C.

    1993-01-01

    An international intercomparison of absolute activity measurements of a solution of Se-75, organized by the Bureau International des Poids et Mesures, France, in 1992, has been carried out. The methodology and results are presented. Source preparation, experimental techniques and measurement system are described. (author). 2 refs

  10. 45 CFR 2516.820 - What types of internal evaluation activities are required of programs?

    Science.gov (United States)

    2010-10-01

    ... required to: (a) Continuously assess management effectiveness, the quality of services provided, and the satisfaction of both participants and service recipients. Internal evaluations should seek frequent feedback... 45 Public Welfare 4 2010-10-01 2010-10-01 false What types of internal evaluation activities are...

  11. International Centre for Theoretical Physics. Scientific Activities in 1983

    International Nuclear Information System (INIS)

    1984-08-01

    The main activities and results of the ICTP during 1983 are reported, according to the following programme components: Physics and energy (Plasma physics; Non-conventional energy; Nuclear physics); Fundamental physics (Elementary particles and fundamental theory); Physics of the living state (Medical physics; Applications of physics to medicine and biology); Physics and technology (Condensed matter physics and related; Atomic, molecular and laser physics; Physics of communications); Mathematics (Applicable mathematics); Physics of the environment and of natural resources (Soil physics; Geophysics); other fields

  12. Recent activity of international comparison for nanoparticle size measurement

    Science.gov (United States)

    Takahashi, Kayori; Takahata, Keiji; Misumi, Ichiko; Sugawara, Kentaro; Gonda, Satoshi; Ehara, Kensei

    2014-08-01

    Nanoparticle sizing is the most fundamental measurement for producing nanomaterials, evaluation of nanostructure, and the risk assessment of nanomaterials for human health. Dynamic light scattering (DLS) is widely used as a useful and convenient technique for determining nanoparticle size in liquid; however, the precision of this technique has been unclear. Some international comparisons are now in progress to verify the measurement accuracy of nanoparticle sizing, as a typical example of Asia Pacific Metrology Programme Supplementary Comparison. In this study, we evaluated the precision of DLS technique for nanoparticle sizing and estimated the uncertainty of the DLS data for polystyrene latex suspensions. The extrapolations of apparent diffusion coefficients to infinite dilution and to lower angles yielded more precise values than those obtained at one angle and one concentration. The extrapolated particle size measured by DLS was compared to the size determined by differential mobility analyzer (DMA), atomic force microscopy (AFM), and scanning electron microscopy (SEM). Before the comparison, the intensity-averaged size measured by DLS was recalculated to the number-averaged size, and the thickness of water layer attaching on the surface of particles were added into uncertainty of particle sizing by DLS. After the recalculation, the consistent values of mean particle diameter were obtained between those by DLS and by DMA, AFM, and SEM within the estimated uncertainties.

  13. 78 FR 37505 - International Standard-Setting Activities

    Science.gov (United States)

    2013-06-21

    ... category: Cereals, Pulses and Legumes Responsible Agency: HHS/FDA. U.S. Participation: Yes. Cocoa Products... the animal product, and include residues of associated impurities of the veterinary drug concerned. An... technical requirements for registration of veterinary medicinal products Draft MRLs for Veterinary Drugs (at...

  14. Literature review on recent international activity in cooperative vehicle-highway automation systems.

    Science.gov (United States)

    2012-12-01

    This literature review supports the report, Recent International Activity in Cooperative VehicleHighway Automation Systems. It : reviews the published literature in English dating from 2007 or later about non-U.S.-based work on cooperative vehicle...

  15. The Interplay of Networking Activities and Internal Knowledge Actions for Subsidiary Influence within MNCs

    DEFF Research Database (Denmark)

    Tavani, Zhaleh Najafi; Giroud, Axèle; Andersson, Ulf

    2012-01-01

    Building on resource dependency theory; this research investigates the joint impacts of subsidiary knowledge based actions (Reverse Knowledge Transfer (RKT) and knowledge development) and networking activities (internal and external embeddedness) on its strategic influence in the multinational co...

  16. International activities concerning seismic effects on underground structures

    International Nuclear Information System (INIS)

    Hakala, W.W.

    1982-01-01

    At the 5th Annual Meeting of the ITA in Atlanta, Georgia, on June 15-17, 1979, the General Assembly approved the formation of the Working Group Seismic Effects on Underground Structures. The objectives of this Working Group are to: (1) collect data on earthquake damage to underground facilities throughout the world; (2) collect information on aseismic design procedures used within the various countries; and (3) synthesize the information and disseminate the results to the member nations of ITA. William W. Hakala of the US was designated the Animateur of the Working Group. The Working Group decided on the following sequential course of action to achieve the stated objectives: (1) continue to develop a bibliograhy on damages to underground structures by dynamic forces. This will be an ongoing activity of the Working Group; (2) each country is to develop a summary of case histories of earthquake damage to underground structures. These case histories will be discussed at the next meeting of the Working Group in order to identify those parameters that permit or prevent such damage; (3) the state-of-the-art paper on earthquake damage to underground opening being prepared in the US (John A. Blume and Associates, Engineers) is presently being printed and will then be distributed to the membership for comment. This report will form the basis for the activities described below; (4) the above activities should lead to a textbook - like document that provides a design philosophy for underground structures subjected to seismic forces; (5) the work tasks will suggest needed research to solve the identified problems. At each Working Group meeting the member nation delegates will provide a summary of research progress in their countries. These research needs will be documented, reviewed, revised, and disseminated on an annual basis

  17. Multi trace element analysis of dry biological materials by neutron activation analysis including a chemical group separation

    International Nuclear Information System (INIS)

    Weers, C.A.

    1980-01-01

    The principles of activation analysis and the practical aspects of neutron activation analysis are outlined. The limits which are set to accuracy and precision are defined. The description of the evaporation process is summarised in terms of the half-volume. This quantity is then used to define the resolving power. The formulation is checked by radiotracer experiments. Dried animal blood is used as the testing material. The pretreatment of the samples and (the development of) the destruction-evaporation apparatus is described. Four successive devices were built and tested. The development of the successive adsorption steps with active charcoal, Al 2 O 3 and coprecipitation with Fe(OH) 3 is presented. Seven groups of about 25 elements in total can be determined this way. The results obtained for standard reference materials are summarized and compared with literature data. (Auth.)

  18. Politics and economics to shape international oil and gas activity

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    This paper reports that political and economic events play unusually strong roles in shaping worldwide oil and gas activity levels this year. Developments in the former U.S.S.R. will be critical. As the now-independent republics adopt new economic systems, production and demand patterns will change, as will exports from what has been the world's leading oil producer. Changing conditions in the Middle East among members of the Organization of Petroleum Exporting countries also will affect the industry in the year following the brief Persian Gulf war. Unless worldwide demand surges unexpectedly, these substantial additions to supply will tend to weaken oil prices in 1992

  19. Future of international cooperative activity for graduate school education in nuclear field

    International Nuclear Information System (INIS)

    Obara, Toru

    2008-01-01

    Further improvement of graduate school education in nuclear field is one of the important issues in universities in nuclear field. The COE-INES program has performed international cooperative activities for graduate school education with foreign universities in nuclear field. There are a lot of possibilities in international cooperation with foreign universities for graduate school education. The use of Internet can be a strong tool for the activities. (author)

  20. Halden Reactor Project activities, achievements and international collaboration

    International Nuclear Information System (INIS)

    Wiesenack, W.

    2003-01-01

    This paper concentrates on the Halden Project research programme related to fuel testing. An overview of ongoing tests on WWER fuel performance is also included. The ongoing and planned experiments containing WWER-related fuels and materials - Irradiation of Standard and Modified WWER Fuel (IFA-503) and Corrosion Testing of Different Cladding Alloys (IFA-638) - are presented. The future experiments involving WWER fuel and cladding types foreseen in of the Halden Reactor Project programme are given

  1. International codes and model intercomparison for intermediate energy activation yields

    International Nuclear Information System (INIS)

    Rolf, M.; Nagel, P.

    1997-01-01

    The motivation for this intercomparison came from data needs of accelerator-based waste transmutation, energy amplification and medical therapy. The aim of this exercise is to determine the degree of reliability of current nuclear reaction models and codes when calculating activation yields in the intermediate energy range up to 5000 MeV. Emphasis has been placed for a wide range of target elements ( O, Al, Fe, Co, Zr and Au). This work is mainly based on calculation of (P,xPyN) integral cross section for incident proton. A qualitative description of some of the nuclear models and code options employed is made. The systematics of graphical presentation of the results allows a quick quantitative measure of agreement or deviation. This code intercomparison highlights the fact that modeling calculations of energy activation yields may at best have uncertainties of a factor of two. The causes of such discrepancies are multi-factorial. Problems are encountered which are connected with the calculation of nuclear masses, binding energies, Q-values, shell effects, medium energy fission and Fermi break-up. (A.C.)

  2. Intergovernmental organisation activities: European Atomic Energy Community, International Atomic Energy Agency, OECD Nuclear Energy Agency

    International Nuclear Information System (INIS)

    Anon.

    2012-01-01

    European Atomic Energy Community: Proposed legislative instruments, Adopted legislative instruments, Non-legislative instruments, Other activities (meetings). International Atomic Energy Agency: IAEA Action Plan on Nuclear Safety. OECD Nuclear Energy Agency: The Russian Federation to join the OECD Nuclear Energy Agency; Participation by the regulatory authorities of India and the United Arab Emirates in the Multinational Design Evaluation Programme (MDEP); NEA International Workshop on Crisis Communication, 9-10 May 2012; International School of Nuclear Law: 2013; Next NEA International Nuclear Law Essentials Course

  3. Assessing Challenges and Opportunities for Education and Communication Activities for International Polar Year 2007-2008

    Science.gov (United States)

    McCaffrey, M. S.

    2005-05-01

    Considerable planning has gone into identifying ways to maximize International Polar Year 2007-2008 (IPY) as a global event that will facilitate the integration of research and education inherent in IPY, and draw the interest and involvement of people around the world. Documents developed through the IPY planning process, including NRC Reports (2004), and drafts reports on education and outreach from the ICSU IPY Planning Group in the Fall of 2004, and the Bridging the Poles workshop of June, 2004, articulate the tremendous potential for IPY beyond the formal research agenda and goals. With less that two years before the start of IPY and fewer than fours years before the activities are completed, these and emerging opportunities face a number of challenges. In addition to the limited time frame remaining to prepare for these activities, participants involved with IPY education and outreach will also need to consider factors such as: uncertain funding for such activities; the lack of established international networks for geoscience education; the need for high level coordination of IPY education and communication; and the creative and intellectual challenge of making the polar regions relevant to people around the world. The planning process has identified six constituencies as key audiences of IPY communication efforts: i) the scientific/research community, ii) young and potentially new polar researchers, iii) the pre-university education community, iv) arctic communities, iv) the general public, and v) decision-makers. Understanding and meeting these audiences' expectations through on-going evaluation and engagement will be key to successful IPY education and outreach efforts. A number of distinct education and outreach projects have been proposed to the ICSU-WMO IPY planning process, such as courses and workshops on specific aspects of IPY, including efforts to address the social and cultural dimension of Arctic peoples. To help meet the challenges, achieve the

  4. Physical activity and performance at school A systematic review of the literature including a methodological quality assessment

    NARCIS (Netherlands)

    Singh, A.S.; Uijtdewilligen, L.; Twisk, J.W.; van Mechelen, W.; Chin A Paw, M.J.M.

    2012-01-01

    Objective: To describe the prospective relationship between physical activity and academic performance. Data Sources: Prospective studies were identified from searches in PubMed, PsycINFO, Cochrane Central, and Sportdiscus from 1990 through 2010. Study Selection: We screened the titles and abstracts

  5. THE MODEL OF FORMATION A PORTFOLIO OF THE INTERNATIONAL ACTIVITIES PROJECTS OF HEI

    Directory of Open Access Journals (Sweden)

    Сергей Васильевич РУДЕНКО

    2016-02-01

    Full Text Available The paper discusses an approach to assessing the project's value of the university international activities, based on the method of expert assessments and fuzzy-multiple method. Evaluating the effectiveness of the university-based project approach is a key factor in its competitiveness. The necessity substantiated of projects valuation of the university international activities. The concept is based on the matrices evaluation value product, process, international activities and development. For integral evaluation value of the university international activities project, we propose viewed from the standpoint of efficiency of all its results. These results can be roughly characterized by the following benchmarks: educational, scientific, technical, political, economic and social. In turn, key benchmarks characterized by its parameters, which estimate conducted by experts. Rating value of the university international activities project is to define the integral indicator of the value of the project. The proposed approach to determining the value of the international activities university projects, based on expert assessments and methods of fuzzy set theory will evaluate the effectiveness of these projects and implement the optimal choice.

  6. Research on Chemical Composition and Biological Properties Including Antiquorum Sensing Activity of Angelica pancicii Vandas Aerial Parts and Roots.

    Science.gov (United States)

    Mileski, Ksenija S; Trifunović, Snežana S; Ćirić, Ana D; Šakić, Željana M; Ristić, Mihailo S; Todorović, Nina M; Matevski, Vlado S; Marin, Petar D; Tešević, Vele V; Džamić, Ana M

    2017-12-20

    The essential oil, different extracts, and isolated compounds of Angelica pancicii Vandas (Apiaceae) were investigated for the first time. The GC-FID and GC-MS analyses revealed sesquiterpenoids as the main constituents of A. pancicii essential oil of aerial parts with bornyl acetate (8.08%), n-octanol (5.82%), kessane (4.26%), and β-selinene (4.26%) as the main constituents. Analysis of methanol extracts, using an HPLC-DAD/ESI-ToF-MS system, showed a total of 52 compounds in the aerial parts and 53 in the roots, indicating coumarins as the main constituents. In addition, new chromone (1) and six known furanocoumarins (2-7) were isolated from the roots and structurally elucidated by combined spectroscopic methods. The aerial part extracts exhibited higher polyphenolic contents and antioxidant activity evaluated by three radical scavenging assays. Using a microwell dilution method, the strongest antibacterial activity profiles were determined for ethanol and methanol root extracts (minimum bactericidal concentrations (MBCs) = 0.25-3.00 mg/mL), which were comparable to the activity of streptomycin (MBCs = 0.34-1.24 mg/mL), while the strongest antibacterial compound of A. pancicii was oxypeucedanin hydrate (MBCs = 0.50-8.00 mg/mL). Antifungal potential was in moderate extent, and the highest activity was obtained for root methanol extract (minimum fungicidal concentrations (MFCs) = 4.00-14.00 mg/mL). Tested sub-minimum inhibitory concentrations (subMICs) of the extracts and isolated compounds inhibited selected Pseudomonas aeruginosa PAO1 virulence determinants. The most reduced growth of P. aeruginosa colony was in the presence of isolated oxypeucedanin. Ethanol (17.36-46.98%) and methanol (34.54-52.43%) root extracts showed higher anti-biofilm activity compared to streptomycin (49.40-88.36%) and ampicillin (56.46-92.16%).

  7. Activities of nuclear training centre in Ljubljana for nuclear community in Slovenia and internationally

    International Nuclear Information System (INIS)

    Stritar, Andrej

    1998-01-01

    It is the vision of the Nuclear Training Centre to be a respected source of knowledge about nuclear technologies in the country and internationally. Our main mission is training of NPP Krsko personnel. For that purpose the training centre was established ten years ago. In addition we are spreading our activities also to other users. We are organizing international training courses, mainly under the sponsorship of the International Atomic Energy Agency. We are also authorized to train professionals, dealing with ionizing radiation in medicine, industry and science. Growing importance is given to our public information activity in our information centre. (author)

  8. ARC (NSC 188491 has identical activity to Sangivamycin (NSC 65346 including inhibition of both P-TEFb and PKC

    Directory of Open Access Journals (Sweden)

    Hollingshead Melinda G

    2009-02-01

    Full Text Available Abstract Background The nucleoside analog, ARC (NSC 188491 is a recently characterized transcriptional inhibitor that selectively kills cancer cells and has the ability to perturb angiogenesis in vitro. In this study, the mechanism of action of ARC was further investigated by comparing in vitro and in vivo activity with other anti-neoplastic purines. Methods Structure-based homology searches were used to identify those compounds with similarity to ARC. Comparator compounds were then evaluated alongside ARC in the context of viability, cell cycle and apoptosis assays to establish any similarities. Following this, biological overlap was explored in detail using gene-expression analysis and kinase inhibition assays. Results Results demonstrated that sangivamycin, an extensively characterized pro-apoptotic nucleoside isolated from Streptomyces, had identical activity to ARC in terms of 1 cytotoxicity assays, 2 ability to induce a G2/M block, 3 inhibitory effects on RNA/DNA/protein synthesis, 4 transcriptomic response to treatment, 5 inhibition of protein kinase C, 6 inhibition of positive transcription elongation factor b (P-TEFb, 7 inhibition of VEGF secretion, and 8 activity within hollow fiber assays. Extending ARC activity to PKC inhibition provides a molecular basis for ARC cancer selectivity and anti-angiogenic effects. Furthermore, functional overlap between ARC and sangivamycin suggests that development of ARC may benefit from a retrospective of previous sangivamycin clinical trials. However, ARC was found to be inactive in several xenograft models, likely a consequence of rapid serum clearance. Conclusion Overall, these data expand on the biological properties of ARC but suggest additional studies are required before it can be considered a clinical trials candidate.

  9. Combatting operational pollution from offshore petroleum activities: international legal regime

    International Nuclear Information System (INIS)

    Vinogradov, S.V.; Wagner, J.P.

    1997-01-01

    Existing global and regional rules and regulations, and regulatory trends, aimed at curbing pollution associated with the normal operation of offshore oil and gas installations are assessed. The designation 'operational pollution' is used to cover a variety of discharges including: oil produced in water; contaminated drill cuttings and muds; sewage; garbage; deck drainage; naturally occurring materials such as radionuclides, heavy metals and aromatics; atmospheric emissions, principally CO 2 , SO x , NO x , CH 4 and volatile organic compounds. The main focus of regulatory attention at present is platform drainage, offshore processing drainage, production water discharge, and displacement discharge. The legal framework considered extends to the appropriate global and regional treaties, ''soft law'' instruments and recommendations. (UK)

  10. Spontaneous cortical activity reveals hallmarks of an optimal internal model of the environment.

    Science.gov (United States)

    Berkes, Pietro; Orbán, Gergo; Lengyel, Máté; Fiser, József

    2011-01-07

    The brain maintains internal models of its environment to interpret sensory inputs and to prepare actions. Although behavioral studies have demonstrated that these internal models are optimally adapted to the statistics of the environment, the neural underpinning of this adaptation is unknown. Using a Bayesian model of sensory cortical processing, we related stimulus-evoked and spontaneous neural activities to inferences and prior expectations in an internal model and predicted that they should match if the model is statistically optimal. To test this prediction, we analyzed visual cortical activity of awake ferrets during development. Similarity between spontaneous and evoked activities increased with age and was specific to responses evoked by natural scenes. This demonstrates the progressive adaptation of internal models to the statistics of natural stimuli at the neural level.

  11. Verification in the international treaty and expected its activities for FMCT

    International Nuclear Information System (INIS)

    Kikuchi, Masahiro

    1997-01-01

    Cold war had been finished and the international society was going to move detente. The mass destruction weapons decrease its object and they are going to be reduced or reversed. By change of the international conditions in the field of non-proliferation, it is necessary to the activities for decreasing atomic weapons and a countermeasure of diffusion of nuclear materials produced by waste and dissection of excess atomic weapon to other countries and stranger. We understand that non-proliferation means a countermeasure of decreasing nuclear weapon. So that the non-proliferation system should be regulated systematically in order to foresee the international tendency in the future and the verification activities to attain reliability assurance of international treaty for disarmament and non-proliferation. NPT reconsider congress decided to begin early negotiation of Fissile Material Cut-off Treaty (FMCT) in 1995. The functions, verification and expected activities of FMCT are discussed. (S.Y.)

  12. Extended automated separation techniques in destructive neutron activation analysis; application to various biological materials, including human tissues and blood

    International Nuclear Information System (INIS)

    Tjioe, P.S.; Goeij, J.J.M. de; Houtman, J.P.W.

    1976-09-01

    Neutron activation analysis may be performed as a multi-element and low-level technique for many important trace elements in biological materials, provided that post-irradiation chemical separations are applied. This paper describes a chemical separation consisting of automated procedures for destruction, distillation, and anion-chromatography. The system developed enables the determination of 14 trace elements in biological materials, viz. antimony, arsenic, bromine, cadmium, chromium, cobalt, copper, gold, iron, mercury, molybdenum, nickel, selenium, and zinc. The aspects of sample preparation, neutron irradiation, gamma-spectrum evaluation, and blank-value contribution are also discussed

  13. African American Youths with Internalizing Difficulties: Relation to Social Support and Activity Involvement

    Science.gov (United States)

    Margolin, Sylvia

    2006-01-01

    Social support and positive activity involvement are considered protective factors that can help offset the risks for youths living in impoverished areas. This study investigated whether insufficient social support and activity involvement are related to internalizing difficulties, such as depression, anxiety, loneliness, and low self-esteem.…

  14. A Decade of International Activities by U.S. Nurse Faculty: A Descriptive Analysis.

    Science.gov (United States)

    Lusk, Brigid; Lash, Ayhan Aytekin

    2002-01-01

    A study to assess scholarly activities of U.S. nursing faculty abroad from 1985-1995 resulted in descriptions of 805 visits to 109 countries by 247 scholars. Results showed that U.S. nurse faculty were involved in diverse and widespread international nursing activities. (Contains 25 references.) (JOW)

  15. Marital Conflict and Growth in Children's Internalizing Symptoms: The Role of Autonomic Nervous System Activity

    Science.gov (United States)

    El-Sheikh, Mona; Keiley, Margaret; Erath, Stephen; Dyer, W. Justin

    2013-01-01

    We assessed trajectories of children's internalizing symptoms, indexed through anxiety and depression, with a focus on the role of interactions between interparental marital conflict, children's sympathetic nervous system activity indexed by skin conductance level (SCL), and parasympathetic nervous system activity indexed by respiratory sinus…

  16. Physical Activity and Psychological Benefits. International Society of Sport Psychology Position Statement.

    Science.gov (United States)

    Physician and Sportsmedicine, 1992

    1992-01-01

    International Society of Sport Psychology clarifies the psychological benefits of physical activity, noting the positive relationship between physical activity level and mental health. Exercise can reduce anxiety, decrease depression levels, reduce neuroticism and anxiety, reduce stress, and have beneficial emotional effects for both sexes across…

  17. The role of internal coupling activities in explaining the effectiveness of open innovation

    DEFF Research Database (Denmark)

    Burcharth, Ana Luiza de Araújo; Knudsen, Mette Præst; Søndergaard, Helle Alsted

    2013-01-01

    This paper investigates the role of internal contingencies in explaining performance implications of open innovation by addressing the questions: does openness drive innovation performance? And if so, what organizational activities impact the effectiveness of both the inbound and the outbound...... finds that the effect of openness is mediated by the use of internal coupling activities that give employees latitude, information and skills to work autonomously. A key result is that the benefits of open innovation are fully captured only when firms adopt a number of activities that provide employees...... with autonomy and empowerment to conduct their work. The paper concludes with implications to theory and practice....

  18. Short-Range Temporal Interactions in Sleep; Hippocampal Spike Avalanches Support a Large Milieu of Sequential Activity Including Replay.

    Directory of Open Access Journals (Sweden)

    J Matthew Mahoney

    Full Text Available Hippocampal neural systems consolidate multiple complex behaviors into memory. However, the temporal structure of neural firing supporting complex memory consolidation is unknown. Replay of hippocampal place cells during sleep supports the view that a simple repetitive behavior modifies sleep firing dynamics, but does not explain how multiple episodes could be integrated into associative networks for recollection during future cognition. Here we decode sequential firing structure within spike avalanches of all pyramidal cells recorded in sleeping rats after running in a circular track. We find that short sequences that combine into multiple long sequences capture the majority of the sequential structure during sleep, including replay of hippocampal place cells. The ensemble, however, is not optimized for maximally producing the behavior-enriched episode. Thus behavioral programming of sequential correlations occurs at the level of short-range interactions, not whole behavioral sequences and these short sequences are assembled into a large and complex milieu that could support complex memory consolidation.

  19. Internal state variable plasticity-damage modeling of AISI 4140 steel including microstructure-property relations: temperature and strain rate effects

    Science.gov (United States)

    Nacif el Alaoui, Reda

    Mechanical structure-property relations have been quantified for AISI 4140 steel. under different strain rates and temperatures. The structure-property relations were used. to calibrate a microstructure-based internal state variable plasticity-damage model for. monotonic tension, compression and torsion plasticity, as well as damage evolution. Strong stress state and temperature dependences were observed for the AISI 4140 steel. Tension tests on three different notched Bridgman specimens were undertaken to study. the damage-triaxiality dependence for model validation purposes. Fracture surface. analysis was performed using Scanning Electron Microscopy (SEM) to quantify the void. nucleation and void sizes in the different specimens. The stress-strain behavior exhibited. a fairly large applied stress state (tension, compression dependence, and torsion), a. moderate temperature dependence, and a relatively small strain rate dependence.

  20. Horizon Expansion of Thermal-Hydraulic Activities into HTGR Safety Analysis Including Gas-Turbine Cycle and Hydrogen Plant

    International Nuclear Information System (INIS)

    No, Hee Cheon; Yoon, Ho Joon; Kim, Seung Jun; Lee, Byeng Jin; Kim, Ji Hwan; Kim, Hyeun Min; Lim, Hong Sik

    2009-01-01

    We present three nuclear/hydrogen-related R and D activities being performed at KAIST: air-ingressed LOCA analysis code development, gas turbine analysis tool development, and hydrogen-production system analysis model development. The ICE numerical technique widely used for the safety analysis of water-reactors is successfully implemented into GAMMA, with which we solve the basic equations for continuity, momentum conservation, energy conservation of the gas mixture, and mass conservation of 6 species (He, N2, O2, CO, CO2, and H2O). GAMMA has been extensively validated using data from 14 test facilities. We developed a tool to predict the characteristics of HTGR helium turbines based on the through flow calculation with a Newton- Raphson method that overcomes the weakness of the conventional method based on the successive iteration scheme. It is found that the current method reaches stable and quick convergence even under the off-normal condition with the same degree of accuracy. The dynamic equations for the distillation column of HI process are described with 4 material components involved in the HI process: H2O, HI, I2, H2. For the HI process we improved the Neumann model based on the NRTL (Non-Random Two-Liquid) model. The improved Neumann model predicted a total pressure with 8.6% maximum relative deviation from the data and 2.5% mean relative deviation, and liquid-liquid-separation with 9.52% maximum relative deviation from the data

  1. Update of the BIPM.RI(II)-K1.Rn-222 comparison of activity measurements for the radionuclide {sup 222}Rn to include the LNE-LNHB, France

    Energy Technology Data Exchange (ETDEWEB)

    Michotte, C.; Ratel, G. [Bureau International de Poids et Mesures, Pavillon de Breteuil, F-92312 Sevres cedex (France); Cassette, P. [Bureau International de Poids et Mesures, Pavillon de Breteuil, F-92312 Sevres cedex (France); Laboratoire national de metrologie et d' essais -Laboratoire national Henri Becquerel, 91191 Gif-sur-Yvette cedex (France)

    2012-02-15

    In 2007, the Laboratoire national de metrologie et d'essais - Laboratoire national Henri Becquerel (LNE-LNHB), France submitted a sample of known activity of {sup 222}Rn to the International Reference System (SIR) for comparison. The value of the activity submitted was about 90 kBq. This key comparison result joins that of Switzerland and Germany in the key comparison database that now contains three results, identifier BIPM.RI(II)-K1.Rn-222. Consequently, the KCRV has been updated and the degrees of equivalence with the KCRV have been evaluated. (authors)

  2. Sociodemographic Moderators of Environment-Physical Activity Associations: Results From the International Prevalence Study.

    Science.gov (United States)

    Perez, Lilian G; Conway, Terry L; Bauman, Adrian; Kerr, Jacqueline; Elder, John P; Arredondo, Elva M; Sallis, James F

    2018-01-01

    Associations between the built environment and physical activity (PA) may vary by sociodemographic factors. However, such evidence from international studies is limited. This study tested the moderating effects of sociodemographic factors on associations between perceived environment and self-reported total PA among adults from the International Prevalence Study. Between 2002 and 2003, adults from 9 countries (N = 10,258) completed surveys assessing total PA (International Physical Activity Questionnaire-short), perceived environment, and sociodemographics (age, gender, and education). Total PA was dichotomized as meeting/not meeting (a) high PA levels and (b) minimum PA guidelines. Logistic models tested environment by sociodemographic interactions (24 total). Education and gender moderated the association between safety from crime and meeting high PA levels (interaction P environment-PA associations. International efforts to improve built environments are needed to promote health-enhancing PA and maintain environmental sustainability.

  3. Internalization mechanisms of the epidermal growth factor receptor after activation with different ligands

    DEFF Research Database (Denmark)

    Henriksen, Lasse; Grandal, Michael Vibo; Knudsen, Stine Louise Jeppe

    2013-01-01

    after ligand activation focuses on the effect of epidermal growth factor (EGF) and transforming growth factor-α (TGF-α). For a long time it was believed that clathrin-mediated endocytosis was the major pathway for internalization of the receptor, but recent work suggests that different pathways exist....... Here we show that clathrin ablation completely inhibits internalization of EGF- and TGF-α-stimulated receptor, however the inhibition of receptor internalization in cells treated with heparin-binding EGF-like growth factor (HB-EGF) or betacellulin (BTC) was only partial. In contrast, clathrin knockdown...... fully inhibits EGFR degradation after all ligands tested. Furthermore, inhibition of dynamin function blocked EGFR internalization after stimulation with all ligands. Knocking out a number of clathrin-independent dynamin-dependent pathways of internalization had no effect on the ligand...

  4. A luciferase-based assay for rapid assessment of drug activity against Mycobacterium tuberculosis including monitoring of macrophage viability.

    Science.gov (United States)

    Larsson, Marie C; Lerm, Maria; Ängeby, Kristian; Nordvall, Michaela; Juréen, Pontus; Schön, Thomas

    2014-11-01

    The intracellular (IC) effect of drugs against Mycobacterium tuberculosis (Mtb) is not well established but increasingly important to consider when combining current and future multidrug regimens into the best possible treatment strategies. For this purpose, we developed an IC model based on a genetically modified Mtb H37Rv strain, expressing the Vibrio harvei luciferase (H37Rv-lux) infecting the human macrophage like cell line THP-1. Cells were infected at a low multiplicity of infection (1:1) and subsequently exposed to isoniazid (INH), ethambutol (EMB), amikacin (AMI) or levofloxacin (LEV) for 5days in a 96-well format. Cell viability was evaluated by Calcein AM and was maintained throughout the experiment. The number of viable H37Rv-lux was determined by luminescence and verified by a colony forming unit analysis. The results were compared to the effects of the same drugs in broth cultures. AMI, EMB and LEV were significantly less effective intracellularly (MIC90: >4mg/L, 8mg/L and 2mg/L, respectively) compared to extracellularly (MIC90: 0.5mg/L for AMI and EMB; 0.25mg/L for LEV). The reverse was the case for INH (IC: 0.064mg/L vs EC: 0.25mg/L). In conclusion, this luciferase based method, in which monitoring of cell viability is included, has the potential to become a useful tool while evaluating the intracellular effects of anti-mycobacterial drugs. Copyright © 2014 Elsevier B.V. All rights reserved.

  5. Developing the Next Generation of International Safeguards and Nonproliferation Experts: Highlights of Select Activities at the National Laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Reed, J; Mathews, C; Kirk, B; Lynch, P; Doyle, J; Meek, E; Pepper, S; Metcalf, R

    2010-03-31

    With many safeguards experts in the United States at or near retirement age, and with the growing and evolving mission of international safeguards, attracting and educating a new generation of safeguards experts is an important element of maintaining a credible and capable international safeguards system. The United States National Laboratories, with their rich experience in addressing the technical and policy challenges of international safeguards, are an important resource for attracting, educating, and training future safeguards experts. This presentation highlights some of the safeguards education and professional development activities underway at the National Laboratories. These include university outreach, summer courses, internships, mid-career transition, knowledge retention, and other projects. The presentation concludes with thoughts on the challenge of interdisciplinary education and the recruitment of individuals with the right balance of skills and backgrounds are recruited to meet tomorrow's needs.

  6. Research and development strategy and maintenance engineering to strengthen the basis of ageing management. International activities

    International Nuclear Information System (INIS)

    Sekimura, Naoto

    2009-01-01

    Systematic development of information basis for database and knowledge-base has been performed in addition to the development of codes and standards by academic societies, regulatory bodies and industries through the intensive domestic safety research collaborations and international collaboration, through the continuous revision of Strategy Maps for Ageing Management and Safe Long Term Operation. Important international activities in IAEA and OECD/NEA especially for knowledge-base and extraction of commendable practices in ageing management are discussed. (author)

  7. Earth observation space programmes, SAFISY activities, strategies of international organisations, legal aspects. Volume 3

    International Nuclear Information System (INIS)

    1992-01-01

    This volume is separated in four sessions. First part is on earth observation space programmes (international earth observation projects and international collaboration, the ERS-1, SPOT and PRIRODA programmes, the first ESA earth observation polar platform and its payload, the future earth observation remote sensing techniques and concepts). The second part is on SAFISY activities (ISY programmes, education and applications, demonstrations and outreach projects). The third part is on programme and strategies of international organisations with respect to earth observation from space. The fourth part is on legal aspects of the use of satellite remote sensing data in Europe. (A.B.). refs., figs., tabs

  8. International coordination of activities for establishing protective measures for the case of accidental release of radioactivity

    Energy Technology Data Exchange (ETDEWEB)

    1986-01-01

    The document discussed here has been submitted to the WHO Regional Committee as a basis for discussion on the international coordination of protective measures in case of large-area radioactive contamination. The document presents the following: a summary of actions taken by the regional office in response to the Chernobyl reactor accident, and of the national and international measures for public health protection after the accident; brief review of actions taken by other international organisations, and the activities proposed by the WHO on a European and on a global level. (orig./HSCH).

  9. Activities of JAEA in the International Science and Technology Center (ISTC)

    International Nuclear Information System (INIS)

    Hamada, Shozo

    2013-05-01

    Since the Headquarter of the International Science and Technology Center (ISTC) was established in Moscow, Russian Federation in 1994, Japan Atomic Energy Agency (JAEA), which includes both Japan Atomic Energy Research Institute and Japan has been made various, considerable contributions as well as participation in partner projects in ISTC activities. By the way, the Russian Federation Party, which is a Government Board Member of ISTC, made the statement that the Russian Federation would withdraw from ISTC until the end of 2015 in the 52th Government Board in held Moscow, 9 December 2010. This is based on the possible consequences of the Executive Order of the President of the Russian Federation dated 11 August 2010 with respect to the withdraw of the Russian Federation from ISTC. So that the Government Board has been discussing about the continuation and/or the establishment of a new organization for ISTC. In any case, the Headquarter of ISTC could stay at Moscow until the end of 2015 at latest. This time is considered as a transition period of ISTC and it is summarized that the collaborations, contributions of JAEA and outcomes from them for ISTC activities in this report. (author)

  10. Comparison between the International Physical Activity Questionnaire and the American College of Sports Medicine/American Heart Association criteria to classify the physical activity profile in adults.

    Science.gov (United States)

    de Moraes, Suzana Alves; Suzuki, Cláudio Shigueki; de Freitas, Isabel Cristina Martins

    2013-01-01

    the study aims to evaluate the reproducibility between the International Physical Activity Questionnaire and the American College of Sports Medicine/American Heart Association criteria to classify the physical activity profile in an adult population living in Ribeirão Preto, SP, Brazil. population-based cross-sectional study, including 930 adults of both genders. The reliability was evaluated by Kappa statistics, estimated according to socio-demographic strata. the kappa estimates showed good agreement between the two criteria in all strata. However, higher prevalence of "actives" was found by using the American College of Sports Medicine/American Heart Association. although the estimates have indicated good agreement, the findings suggest caution in choosing the criteria to classify physical activity profile mainly when "walking" is the main modality of physical activity.

  11. High water-stressed population estimated by world water resources assessment including human activities under SRES scenarios

    Science.gov (United States)

    Kiguchi, M.; Shen, Y.; Kanae, S.; Oki, T.

    2009-04-01

    In an argument of the reduction and the adaptation for the climate change, the evaluation of the influence by the climate change is important. When we argue in adaptation plan from a damage scale and balance with the cost, it is particularly important. Parry et al (2001) evaluated the risks in shortage of water, malaria, food, the risk of the coast flood by temperature function and clarified the level of critical climate change. According to their evaluation, the population to be affected by the shortage of water suddenly increases in the range where temperature increases from 1.5 to 2.0 degree in 2080s. They showed how much we need to reduce emissions in order to draw-down significantly the number at risk. This evaluation of critical climate change threats and targets of water shortage did not include the water withdrawal divided by water availability. Shen et al (2008a) estimated the water withdrawal of projection of future world water resources according to socio-economic driving factors predicted for scenarios A1b, A2, B1, and B2 of the Special Report on Emission Scenarios (SRES). However, these results were in function of not temperature but time. The assessment of the highly water-stressed population considered the socioeconomic development is necessary for a function of the temperature. Because of it is easy to understand to need to reduce emission. We present a multi-GCM analysis of the global and regional populations lived in highly water-stressed basin for a function of the temperature using the socioeconomic data and the outputs of GCMs. In scenario A2, the population increases gradually with warming. On the other hand, the future projection population in scenario A1b and B1 increase gradually until the temperature anomaly exceeds around from +1 to +1.5 degree. After that the population is almost constant. From Shen et al (2008b), we evaluated the HWSP and its ratio in the world with temperature function for scenarios A1B, A2, and B1 by the index of W

  12. The International Prevalence Study on Physical Activity: results from 20 countries

    Directory of Open Access Journals (Sweden)

    Bowles Heather R

    2009-03-01

    Full Text Available Abstract Background Physical activity (PA is one of the most important factors for improving population health, but no standardised systems exist for international surveillance. The International Physical Activity Questionnaire (IPAQ was developed for international surveillance. The purpose of this study was a comparative international study of population physical activity prevalence across 20 countries. Methods Between 2002–2004, a standardised protocol using IPAQ was used to assess PA participation in 20 countries [total N = 52,746, aged 18–65 years]. The median survey response rate was 61%. Physical activity levels were categorised as "low", "moderate" and "high". Age-adjusted prevalence estimates are presented by sex. Results The prevalence of "high PA" varied from 21–63%; in eight countries high PA was reported for over half of the adult population. The prevalence of "low PA" varied from 9% to 43%. Males more frequently reported high PA than females in 17 of 20 countries. The prevalence of low PA ranged from 7–41% among males, and 6–49% among females. Gender differences were noted, especially for younger adults, with males more active than females in most countries. Markedly lower physical activity prevalence (10% difference with increasing age was noted in 11 of 19 countries for males, but only in three countries for women. The ways populations accumulated PA differed, with some reporting mostly vigorous intensity activities and others mostly walking. Conclusion This study demonstrated the feasibility of international PA surveillance, and showed that IPAQ is an acceptable surveillance instrument, at least within countries. If assessment methods are used consistently over time, trend data will inform countries about the success of their efforts to promote physical activity.

  13. International Heart Valve Bank Survey: A Review of Processing Practices and Activity Outcomes

    Science.gov (United States)

    Albrecht, Helmi; Lim, Yeong Phang; Manning, Linda

    2013-01-01

    A survey of 24 international heart valve banks was conducted to acquire information on heart valve processing techniques used and outcomes achieved. The objective was to provide an overview of heart valve banking activities for tissue bankers, tissue banking associations, and regulatory bodies worldwide. Despite similarities found for basic manufacturing processes, distinct differences in procedural details were also identified. The similarities included (1) use of sterile culture media for procedures, (2) antibiotic decontamination, (3) use of dimethyl sulfoxide (DMSO) as a cryoprotectant, (4) controlled rate freezing for cryopreservation, and (5) storage at ultralow temperatures of below −135°C. Differences in procedures included (1) type of sterile media used, (2) antibiotics combination, (3) temperature and duration used for bioburden reduction, (4) concentration of DMSO used for cryopreservation, and (5) storage duration for released allografts. For most banks, the primary reasons why allografts failed to meet release criteria were positive microbiological culture and abnormal morphology. On average, 85% of allografts meeting release criteria were implanted, with valve size and type being the main reasons why released allografts were not used clinically. The wide variation in percentage of allografts meeting release requirements, despite undergoing validated manufacturing procedures, justifies the need for regular review of important outcomes as cited in this paper, in order to encourage comparison and improvements in the HVBs' processes. PMID:24163756

  14. Research in Biological and Medical Sciences, Including Biochemistry, Communicable Disease and Immunology, Internal Medicine, Nuclear Medicine, Physiology, Psychiatry, Surgery and Veterinary Medicine. Volume 2

    Science.gov (United States)

    1975-07-01

    during the past fiscal year include 45 ovario- hysterectomles, one caesarean section, one fracture repair, one patent ductus arteriosus repair, one...Following closure of the thoracotomy, SOD was down by 60% and VQJ was> 80% of control levels. SOD and VQO did not relate to each other in a parallel...tions. Two patents were applied for, one for the Electronic Debubbler Circuit and one for the Improved Flow Cell. A paper on this latest

  15. IFMIF : International Fusion Materials Irradiation Facility Conceptual Design Activity: Executive summary

    International Nuclear Information System (INIS)

    1997-01-01

    This report is a summary of the results of the Conceptual Design Activity (CDA) on the International Fusion Materials Irradiation Facility (IFMIF), conducted during 1995 and 1996. The activity is under the auspices of the International Energy Agency (IEA) Implementing Agreement for a Programme of Research and Development on Fusion Materials. An IEA Fusion Materials Executive Subcommittee was charged with overseeing the IFMIF-CDA work. Participants in the CDA are the European Union, Japan, and the United States, with the Russian Federation as an associate member

  16. IFMIF : International Fusion Materials Irradiation Facility Conceptual Design Activity: Executive summary

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-01-01

    This report is a summary of the results of the Conceptual Design Activity (CDA) on the International Fusion Materials Irradiation Facility (IFMIF), conducted during 1995 and 1996. The activity is under the auspices of the International Energy Agency (IEA) Implementing Agreement for a Programme of Research and Development on Fusion Materials. An IEA Fusion Materials Executive Subcommittee was charged with overseeing the IFMIF-CDA work. Participants in the CDA are the European Union, Japan, and the United States, with the Russian Federation as an associate member.

  17. IFMIF : International Fusion Materials Irradiation Facility Conceptual Design Activity: Final report

    International Nuclear Information System (INIS)

    Martone, M.

    1997-01-01

    This report documents the results of the Conceptual Design Activity (CDA) on the International Fusion Materials Irradiation Facility (IFMIF), conducted during 1995 and 1996. The activity is under the auspices of the International Energy Agency (IEA) Implementing Agreement for a Programme of Research and Development on Fusion Materials. An IEA Fusion Materials Executive Subcommittee was charged with overseeing the IFMIF-CDA work. Participants in the CDA are the European Union, Japan, and the United States, with the Russian Federation as an associate member

  18. IFMIF : International Fusion Materials Irradiation Facility Conceptual Design Activity: Final report

    Energy Technology Data Exchange (ETDEWEB)

    Martone, M [ENEA, Centro Ricerche Frascati, Rome (Italy)

    1997-01-01

    This report documents the results of the Conceptual Design Activity (CDA) on the International Fusion Materials Irradiation Facility (IFMIF), conducted during 1995 and 1996. The activity is under the auspices of the International Energy Agency (IEA) Implementing Agreement for a Programme of Research and Development on Fusion Materials. An IEA Fusion Materials Executive Subcommittee was charged with overseeing the IFMIF-CDA work. Participants in the CDA are the European Union, Japan, and the United States, with the Russian Federation as an associate member.

  19. International

    International Nuclear Information System (INIS)

    Anon.

    1997-01-01

    This rubric reports on 10 short notes about international economical facts about nuclear power: Electricite de France (EdF) and its assistance and management contracts with Eastern Europe countries (Poland, Hungary, Bulgaria); Transnuclear Inc. company (a 100% Cogema daughter company) acquired the US Vectra Technologies company; the construction of the Khumo nuclear power plant in Northern Korea plays in favour of the reconciliation between Northern and Southern Korea; the delivery of two VVER 1000 Russian reactors to China; the enforcement of the cooperation agreement between Euratom and Argentina; Japan requested for the financing of a Russian fast breeder reactor; Russia has planned to sell a floating barge-type nuclear power plant to Indonesia; the control of the Swedish reactor vessels of Sydkraft AB company committed to Tractebel (Belgium); the renewal of the nuclear cooperation agreement between Swiss and USA; the call for bids from the Turkish TEAS electric power company for the building of the Akkuyu nuclear power plant answered by three candidates: Atomic Energy of Canada Limited (AECL), Westinghouse (US) and the French-German NPI company. (J.S.)

  20. A thermal extrapolation method for the effective temperatures and internal energies of activated ions

    Science.gov (United States)

    Meot-Ner (Mautner), Michael; Somogyi, Árpád

    2007-11-01

    The internal energies of dissociating ions, activated chemically or collisionally, can be estimated using the kinetics of thermal dissociation. The thermal Arrhenius parameters can be combined with the observed dissociation rate of the activated ions using kdiss = Athermalexp(-Ea,thermal/RTeff). This Arrhenius-type relation yields the effective temperature, Teff, at which the ions would dissociate thermally at the same rate, or yield the same product distributions, as the activated ions. In turn, Teff is used to calculate the internal energy of the ions and the energy deposited by the activation process. The method yields an energy deposition efficiency of 10% for a chemical ionization proton transfer reaction and 8-26% for the surface collisions of various peptide ions. Internal energies of ions activated by chemical ionization or by gas phase collisions, and of ions produced by desorption methods such as fast atom bombardment, can be also evaluated. Thermal extrapolation is especially useful for ion-molecule reaction products and for biological ions, where other methods to evaluate internal energies are laborious or unavailable.

  1. Documentation of the status of international geothermal power plants and a list by country of selected geothermally active governmental and private sector entities

    Energy Technology Data Exchange (ETDEWEB)

    1992-10-01

    This report includes the printouts from the International Geothermal Power Plant Data Base and the Geothermally Active Entity Data Base. Also included are the explanation of the abbreviations used in the power plant data base, maps of geothermal installations by country, and data base questionnaires and mailing lists.

  2. Documentation of the status of international geothermal power plants and a list by country of selected geothermally active governmental and private sector entities

    International Nuclear Information System (INIS)

    1992-10-01

    This report includes the printouts from the International Geothermal Power Plant Data Base and the Geothermally Active Entity Data Base. Also included are the explanation of the abbreviations used in the power plant data base, maps of geothermal installations by country, and data base questionnaires and mailing lists

  3. Evolution of the international workshops on quantitative structure-activity relationships (QSARs) in environmental toxicology.

    Science.gov (United States)

    Kaiser, K L E

    2007-01-01

    This presentation will review the evolution of the workshops from a scientific and personal perspective. From their modest beginning in 1983, the workshops have developed into larger international meetings, regularly held every two years. Their initial focus on the aquatic sphere soon expanded to include properties and effects on atmospheric and terrestrial species, including man. Concurrent with this broadening of their scientific scope, the workshops have become an important forum for the early dissemination of all aspects of qualitative and quantitative structure-activity research in ecotoxicology and human health effects. Over the last few decades, the field of quantitative structure/activity relationships (QSARs) has quickly emerged as a major scientific method in understanding the properties and effects of chemicals on the environment and human health. From substances that only affect cell membranes to those that bind strongly to a specific enzyme, QSARs provides insight into the biological effects and chemical and physical properties of substances. QSARs are useful for delineating the quantitative changes in biological effects resulting from minor but systematic variations of the structure of a compound with a specific mode of action. In addition, more holistic approaches are being devised that result in our ability to predict the effects of structurally unrelated compounds with (potentially) different modes of action. Research in QSAR environmental toxicology has led to many improvements in the manufacturing, use, and disposal of chemicals. Furthermore, it has led to national policies and international agreements, from use restrictions or outright bans of compounds, such as polychlorinated biphenyls (PCBs), mirex, and highly chlorinated pesticides (e.g. DDT, dieldrin) for the protection of avian predators, to alternatives for ozone-depleting compounds, to better waste treatment systems, to more powerful and specific acting drugs. Most of the recent advances

  4. Creating Entrustable Professional Activities to Assess Internal Medicine Residents in Training: A Mixed-Methods Approach.

    Science.gov (United States)

    Taylor, David R; Park, Yoon Soo; Smith, Christopher A; Karpinski, Jolanta; Coke, William; Tekian, Ara

    2018-05-15

    Competency-based medical education has not advanced residency training as much as many observers expected. Some medical educators now advocate reorienting competency-based approaches to focus on a resident's ability to do authentic clinical work. To develop descriptions of clinical work for which internal medicine residents must gain proficiency to deliver meaningful patient care (for example, "Admit and manage a medical inpatient with a new acute problem"). A modified Delphi process involving clinical experts followed by a conference of educational experts. The Royal College of Physicians and Surgeons of Canada. In phase 1 of the project, members of the Specialty Committee for Internal Medicine participated in a modified Delphi process to identify activities in internal medicine that represent the scope of the specialty. In phase 2 of the project, 5 experts who were scholars and leaders in competency-based medical education reviewed the results. Phase 1 identified important activities, revised descriptions to improve accuracy and avoid overlap, and assigned activities to stages of training. Phase 2 compared proposed activity descriptions with published guidelines for their development and application in medical education. The project identified 29 activities that qualify as entrustable professional activities. The project also produced a detailed description of each activity and guidelines for using them to assess residents. These activities reflect the practice patterns of the developers and may not fully represent internal medicine practice in Canada. Identification of these activities is expected to facilitate modification of training and assessment programs for medical residents so that programs focus less on isolated skills and more on integrated tasks. Southeastern Ontario Academic Medical Organization Endowed Scholarship and Education Fund and Queen's University Department of Medicine Innovation Fund.

  5. Types of internal facilitation activities in hospitals implementing evidence-based interventions.

    Science.gov (United States)

    Baloh, Jure; Zhu, Xi; Ward, Marcia M

    2017-01-25

    Implementation models, frameworks, and theories recognize the importance of activities that facilitate implementation success. However, little is known about internal facilitation activities that hospital personnel engage in during implementation efforts. The aim of the study was to examine internal facilitation activities at 10 critical access hospitals in rural Iowa during their implementation of TeamSTEPPS, a patient safety intervention, and to identify characteristics that distinguish different types of facilitation activities. We followed 10 critical access hospitals for 2 years after the onset of implementation, conducting quarterly interviews with key informants. On the basis of the transcripts from the first two quarters, a coding template was developed using inductive analyses. The template was then applied deductively to code all interview transcripts. Using comparative analysis, we examined the characteristics that distinguish between the facilitation types. We identified four types of facilitation activities-Leadership, Buy-in, Customization, and Accountability. Individuals and teams engaged in different types of facilitation activities, both in a planned and an ad hoc manner. These activities targeted at both people and practices and exhibited varying temporal patterns (start and peak time). There are four types of facilitation activities that hospitals engage in while implementing evidence-based practices, offering a parsimonious way to characterize facilitation activities. New theoretical and empirical research opportunities are discussed. Understanding the types of facilitation activities and their distinguishing characteristics can assist managers in planning and executing implementations of evidence-based interventions.

  6. The increasing globalization of health librarianship: a brief survey of international trends and activities.

    Science.gov (United States)

    Madge, Bruce; Plutchak, T Scott

    2005-09-01

    Throughout his career, Leslie Morton was interested in international developments in health librarianship. In memory of the work he did in this field, the authors examine current developments in international health librarianship and describe some current themes. The authors draw from their combined experience in international activities and the published information available from selected library associations and related organizations. Although many of the major health library associations around the world are tackling agendas specific to their own country, issues of international concern are emerging in common. These are grouped around globalization, partnerships and co-operation, electronic access, especially open access, and working with the developing world in a number of different ways. Of course, the basis of all of these initiatives is to improve the health of the population by providing the best possible access to materials. Professional associations can provide a useful institutional infrastructure for addressing issues of international interest. Librarians should encourage their associations to develop these international initiatives and to seek out new and innovative ways to work together across international boundaries.

  7. Internal exposure to neutron-activated {sup 56}Mn dioxide powder in Wistar rats. Pt. 1. Dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    Stepanenko, Valeriy; Kaprin, Andrey; Galkin, Vsevolod; Ivanov, Sergey; Kolyzhenkov, Timofey; Petukhov, Aleksey; Yaskova, Elena; Belukha, Irina; Khailov, Artem; Skvortsov, Valeriy; Ivannikov, Alexander; Akhmedova, Umukusum; Bogacheva, Viktoria [Medical Radiological Research Center (MRRC) named after A.F. Tsyb - National Medical Research Radiological Center of the Health Ministry of the Russian Federation, Obninsk, Kaluga Region (Russian Federation); Rakhypbekov, Tolebay; Dyussupov, Altay; Chaizhunusova, Nailya; Sayakenov, Nurlan; Uzbekov, Darkhan; Saimova, Aisulu; Shabdarbaeva, Dariya; Kairkhanova, Yankar [Semey State Medical University, Semey (Kazakhstan); Otani, Keiko; Endo, Satoru; Satoh, Kenichi; Kawano, Noriyuki; Fujimoto, Nariaki; Hoshi, Masaharu [Hiroshima University, Hiroshima (Japan); Shichijo, Kazuko; Nakashima, Masahiro; Takatsuji, Toshihiro [Nagasaki University, Nagasaki (Japan); Sakaguchi, Aya; Kato, Hiroaki; Onda, Yuichi [University of Tsukuba, Ibaraki (Japan); Toyoda, Shin [Okayama University of Science, Okayama (Japan); Sato, Hitoshi [Ibaraki Prefectural University of Health Science, Ibaraki (Japan); Skakov, Mazhin; Vurim, Alexandr; Gnyrya, Vyacheslav; Azimkhanov, Almas; Kolbayenkov, Alexander [National Nuclear Center of the Republic of Kazakhstan, Kurchatov (Kazakhstan); Zhumadilov, Kasym [Eurasian National University named after L.N. Gumilyov, Astana (Kazakhstan)

    2017-03-15

    There were two sources of ionizing irradiation after the atomic bombings of Hiroshima and Nagasaki: (1) initial gamma-neutron irradiation at the moment of detonation and (2) residual radioactivity. Residual radioactivity consisted of two components: radioactive fallout containing fission products, including radioactive fissile materials from nuclear device, and neutron-activated radioisotopes from materials on the ground. The dosimetry systems DS86 and DS02 were mainly devoted to the assessment of initial radiation exposure to neutrons and gamma rays, while only brief considerations were given for the estimation of doses caused by residual radiation exposure. Currently, estimation of internal exposure of atomic bomb survivors due to dispersed radioactivity and neutron-activated radioisotopes from materials on the ground is a matter of some interest, in Japan. The main neutron-activated radionuclides in soil dust were {sup 24}Na, {sup 28}Al, {sup 31}Si, {sup 32}P, {sup 38}Cl, {sup 42}K, {sup 45}Ca, {sup 46}Sc, {sup 56}Mn, {sup 59}Fe, {sup 60}Co, and {sup 134}Cs. The radionuclide {sup 56}Mn (T{sub 1/2} = 2.58 h) is known as one of the dominant beta- and gamma emitters during the first few hours after neutron irradiation of soil and other materials on ground, dispersed in the form of dust after a nuclear explosion in the atmosphere. To investigate the peculiarities of biological effects of internal exposure to {sup 56}Mn in comparison with external gamma irradiation, a dedicated experiment with Wistar rats exposed to neutron-activated {sup 56}Mn dioxide powder was performed recently by Shichijo and coworkers. The dosimetry required for this experiment is described here. Assessment of internal radiation doses was performed on the basis of measured {sup 56}Mn activity in the organs and tissues of the rats and of absorbed fractions of internal exposure to photons and electrons calculated with the MCNP-4C Monte Carlo using a mathematical rat phantom. The first results of

  8. Proposal to consistently apply the International Code of Nomenclature of Prokaryotes (ICNP) to names of the oxygenic photosynthetic bacteria (cyanobacteria), including those validly published under the International Code of Botanical Nomenclature (ICBN)/International Code of Nomenclature for algae, fungi and plants (ICN), and proposal to change Principle 2 of the ICNP.

    Science.gov (United States)

    Pinevich, Alexander V

    2015-03-01

    This taxonomic note was motivated by the recent proposal [Oren & Garrity (2014) Int J Syst Evol Microbiol 64, 309-310] to exclude the oxygenic photosynthetic bacteria (cyanobacteria) from the wording of General Consideration 5 of the International Code of Nomenclature of Prokaryotes (ICNP), which entails unilateral coverage of these prokaryotes by the International Code of Nomenclature for algae, fungi, and plants (ICN; formerly the International Code of Botanical Nomenclature, ICBN). On the basis of key viewpoints, approaches and rules in the systematics, taxonomy and nomenclature of prokaryotes it is reciprocally proposed to apply the ICNP to names of cyanobacteria including those validly published under the ICBN/ICN. For this purpose, a change to Principle 2 of the ICNP is proposed to enable validation of cyanobacterial names published under the ICBN/ICN rules. © 2015 IUMS.

  9. 78 FR 36523 - Foreign-Trade Zone 84-Houston, Texas; Authorization of Production Activity; Toshiba International...

    Science.gov (United States)

    2013-06-18

    ... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [B-17-2013] Foreign-Trade Zone 84--Houston, Texas; Authorization of Production Activity; Toshiba International Corporation; (Hybrid Electric Vehicle Motors and Generators Production); Houston, Texas On February 11, 2013, the Port of Houston Authority, grantee of FTZ 84...

  10. Advancing science and policy through a coordinated international study of physical activity and built environments

    DEFF Research Database (Denmark)

    Kerr, Jacqueline; Sallis, James F; Owen, Neville

    2013-01-01

    National and international strategies to increase physical activity emphasize environmental and policy changes that can have widespread and long-lasting impact. Evidence from multiple countries using comparable methods is required to strengthen the evidence base for such initiatives. Because some...

  11. International business activities of German producers of petroleum and natural gas; Auslandsaktivitaeten deutscher Erdoel-/Erdgasproduzenten

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    2008-04-15

    The contribution reports on international business activities of the following German companies: RWE Dea; Petro-Canada; E.ON Ruhrgas; EWE; Bayerngas. [German] Es wird ueber die Auslandsaktivitaeten folgender deutscher Firmen berichtet: Wintershall; RWE Dea; Petro-Canada; E.ON Ruhrgas; EWE; Bayerngas.

  12. Cesic: optomechanical technology last development results and new HBCesic highly light weighted space mirror development including corrective function 7th international conference on space optics, october 2008

    Science.gov (United States)

    Devilliers, Christophe; Kroedel, Mathias

    2017-11-01

    18 Kg/m2 has been designed, sized and manufactured and is currently under polishing at SESO. The polishing to a micro-roughness of far less than 20 nm RMS without expensive overcoatings has been already validated on mirrors up to 800 mm. This 600 mm mirror will be polished to a WFE of less than 20 nm, and afterwards the mirror will be tested under cryogenic environment to measure the WFE evolution between ambient and cryo. The mirror is equipped with a system for focus and astigmatism modification. During the cryo test this system will be activated at cryo temperature to also demonstrate the function of this system. This correction system is developed for future large mirrors for interferometric nulling or aperture synthesis missions like the Darwin mission . For such missions very large and very lightweight mirrors up to 3,5 m diameter with an areal density of less than 25 Kg/m2 are required and thank to the HBCesictechnology such performance is now feasible.

  13. Contribution of NADPH Oxidase to Membrane CD38 Internalization and Activation in Coronary Arterial Myocytes

    Science.gov (United States)

    Xu, Ming; Li, Xiao-Xue; Ritter, Joseph K.; Abais, Justine M.; Zhang, Yang; Li, Pin-Lan

    2013-01-01

    The CD38-ADP-ribosylcyclase-mediated Ca2+ signaling pathway importantly contributes to the vasomotor response in different arteries. Although there is evidence indicating that the activation of CD38-ADP-ribosylcyclase is associated with CD38 internalization, the molecular mechanism mediating CD38 internalization and consequent activation in response to a variety of physiological and pathological stimuli remains poorly understood. Recent studies have shown that CD38 may sense redox signals and is thereby activated to produce cellular response and that the NADPH oxidase isoform, NOX1, is a major resource to produce superoxide (O2 ·−) in coronary arterial myocytes (CAMs) in response to muscarinic receptor agonist, which uses CD38-ADP-ribosylcyclase signaling pathway to exert its action in these CAMs. These findings led us hypothesize that NOX1-derived O2 ·− serves in an autocrine fashion to enhance CD38 internalization, leading to redox activation of CD38-ADP-ribosylcyclase activity in mouse CAMs. To test this hypothesis, confocal microscopy, flow cytometry and a membrane protein biotinylation assay were used in the present study. We first demonstrated that CD38 internalization induced by endothelin-1 (ET-1) was inhibited by silencing of NOX1 gene, but not NOX4 gene. Correspondingly, NOX1 gene silencing abolished ET-1-induced O2 ·− production and increased CD38-ADP-ribosylcyclase activity in CAMs, while activation of NOX1 by overexpression of Rac1 or Vav2 or administration of exogenous O2 ·− significantly increased CD38 internalization in CAMs. Lastly, ET-1 was found to markedly increase membrane raft clustering as shown by increased colocalization of cholera toxin-B with CD38 and NOX1. Taken together, these results provide direct evidence that Rac1-NOX1-dependent O2 ·− production mediates CD38 internalization in CAMs, which may represent an important mechanism linking receptor activation with CD38 activity in these cells. PMID:23940720

  14. Activation of AMP-activated protein kinase rapidly suppresses multiple pro-inflammatory pathways in adipocytes including IL-1 receptor-associated kinase-4 phosphorylation

    DEFF Research Database (Denmark)

    Mancini, Sarah J; White, Anna D; Bijland, Silvia

    2017-01-01

    Inflammation of adipose tissue in obesity is associated with increased IL-1β, IL-6 and TNF-α secretion and proposed to contribute to insulin resistance. AMP-activated protein kinase (AMPK) regulates nutrient metabolism and is reported to have anti-inflammatory actions in adipose tissue, yet the m...

  15. The International Atomic Energy Agency's activities in radiation medicine and cancer: promoting global health through diplomacy.

    Science.gov (United States)

    Deatsch-Kratochvil, Amanda N; Pascual, Thomas Neil; Kesner, Adam; Rosenblatt, Eduardo; Chhem, Rethy K

    2013-02-01

    Global health has been an issue of seemingly low political importance in comparison with issues that have direct bearing on countries' national security. Recently, health has experienced a "political revolution" or a rise in political importance. Today, we face substantial global health challenges, from the spread of infectious disease, gaps in basic maternal and child health care, to the globalization of cancer. A recent estimate states that the "overall lifetime risk of developing cancer (both sexes) is expected to rise from more than one in three to one in two by 2015." These issues pose significant threats to international health security. To successfully combat these grave challenges, the international community must embrace and engage in global health diplomacy, defined by scholars Thomas Novotny and Vicanne Adams as a political activity aimed at improving global health, while at the same time maintaining and strengthening international relations. The IAEA (International Atomic Energy Agency) is an international organization with a unique mandate to "accelerate and enlarge the contribution of atomic energy to peace, health, and prosperity throughout the world." This article discusses global health diplomacy, reviews the IAEA's program activities in human health by focusing on radiation medicine and cancer, and the peaceful applications of atomic energy within the context of global health diplomacy. Copyright © 2013 Canadian Association of Radiologists. Published by Elsevier Inc. All rights reserved.

  16. NASA Activity Update for the 2013 Unmanned Vehicle Systems International (UVSI) Yearbook

    Science.gov (United States)

    Bauer, Jeffrey E.

    2013-01-01

    This year s report offers a high level perspective on some of the UAS related activities in which NASA is involved, both internal and external to the agency. Internally, NASA issued UAS operational policy on certification of NASA UAS and aircrew. A team of NASA UAS experts and operators analyzed all current procedures and best practices to design the policy. An update to the agencies Aircraft Operations Management Manual incorporated a new chapter to address UAS planning, preflight operations, flight operations, flight crew requirements, airworthiness and flight safety reviews. NASA UAS are classified into three categories based on weight and airspeed. Aircrews, including observers, are classified by how they interface with the UAS, and the policy defines qualifications, training, and currency. The NASA flight readiness approval process identifies risks and mitigations in order to reduce the likelihood and/or consequence of the risk to an acceptable level. The UAS operations process incorporates all aspects of airworthiness, flight standards and range safety exactly the same processes used for NASA manned aircraft operations. NASA has two internal organizations that routinely operate UAS. The Science Mission Directorate utilizes UAS as part of its Airborne Science Program and is the most frequent operator of NASA UAS in both national and international airspace. The Aeronautics Research Mission Directorate conducts UAS flight operations in addition to conducting research important to the UAS community. This past year the Science Mission Directorate supported the Hurricane and Severe Storm Sentimental (HS3) Mission with two NASA Global Hawk platforms. HS3 is a five-year mission specifically targeted to investigate the processes that underlie hurricane formation. During the 2012 portion of this mission the Global Hawk overflew hurricanes Leslie and Nadine in the Atlantic Ocean completing 6 flights and accumulating more than 148 flight hours. Another multi-year mission

  17. Internal Audit and Internal Control Institutions as Legal Prevention Means of Vialations in the Sphere of Economic Financial Activities

    Directory of Open Access Journals (Sweden)

    Lvova I. G.

    2012-05-01

    Full Text Available The article deals with the issues of similarities and differences between the concepts of “internal control” and “internal audit”. The author analyzes the existing approaches in current legislation and current scientific literature, the approaches to the concepts of “internal control” and “internal audit” in respect to their goals, objectives and legal regulation at this stage

  18. Internalization mechanisms of the epidermal growth factor receptor after activation with different ligands.

    Directory of Open Access Journals (Sweden)

    Lasse Henriksen

    Full Text Available The epidermal growth factor receptor (EGFR regulates normal growth and differentiation, but dysregulation of the receptor or one of the EGFR ligands is involved in the pathogenesis of many cancers. There are eight ligands for EGFR, however most of the research into trafficking of the receptor after ligand activation focuses on the effect of epidermal growth factor (EGF and transforming growth factor-α (TGF-α. For a long time it was believed that clathrin-mediated endocytosis was the major pathway for internalization of the receptor, but recent work suggests that different pathways exist. Here we show that clathrin ablation completely inhibits internalization of EGF- and TGF-α-stimulated receptor, however the inhibition of receptor internalization in cells treated with heparin-binding EGF-like growth factor (HB-EGF or betacellulin (BTC was only partial. In contrast, clathrin knockdown fully inhibits EGFR degradation after all ligands tested. Furthermore, inhibition of dynamin function blocked EGFR internalization after stimulation with all ligands. Knocking out a number of clathrin-independent dynamin-dependent pathways of internalization had no effect on the ligand-induced endocytosis of the EGFR. We suggest that EGF and TGF-α lead to EGFR endocytosis mainly via the clathrin-mediated pathway. Furthermore, we suggest that HB-EGF and BTC also lead to EGFR endocytosis via a clathrin-mediated pathway, but can additionally use an unidentified internalization pathway or better recruit the small amount of clathrin remaining after clathrin knockdown.

  19. Internalization Mechanisms of the Epidermal Growth Factor Receptor after Activation with Different Ligands

    Science.gov (United States)

    Henriksen, Lasse; Grandal, Michael Vibo; Knudsen, Stine Louise Jeppe; van Deurs, Bo; Grøvdal, Lene Melsæther

    2013-01-01

    The epidermal growth factor receptor (EGFR) regulates normal growth and differentiation, but dysregulation of the receptor or one of the EGFR ligands is involved in the pathogenesis of many cancers. There are eight ligands for EGFR, however most of the research into trafficking of the receptor after ligand activation focuses on the effect of epidermal growth factor (EGF) and transforming growth factor-α (TGF-α). For a long time it was believed that clathrin-mediated endocytosis was the major pathway for internalization of the receptor, but recent work suggests that different pathways exist. Here we show that clathrin ablation completely inhibits internalization of EGF- and TGF-α-stimulated receptor, however the inhibition of receptor internalization in cells treated with heparin-binding EGF-like growth factor (HB-EGF) or betacellulin (BTC) was only partial. In contrast, clathrin knockdown fully inhibits EGFR degradation after all ligands tested. Furthermore, inhibition of dynamin function blocked EGFR internalization after stimulation with all ligands. Knocking out a number of clathrin-independent dynamin-dependent pathways of internalization had no effect on the ligand-induced endocytosis of the EGFR. We suggest that EGF and TGF-α lead to EGFR endocytosis mainly via the clathrin-mediated pathway. Furthermore, we suggest that HB-EGF and BTC also lead to EGFR endocytosis via a clathrin-mediated pathway, but can additionally use an unidentified internalization pathway or better recruit the small amount of clathrin remaining after clathrin knockdown. PMID:23472148

  20. Breastfeeding and Active Bonding Protects against Children’s Internalizing Behavior Problems

    Directory of Open Access Journals (Sweden)

    Jianghong Liu

    2013-12-01

    Full Text Available Breastfeeding is associated with numerous health benefits to offspring and mothers and may improve maternal-infant bonding. Ample evidence suggests breastfeeding can improve child neurodevelopment, but more research is needed to establish whether breastfeeding is linked to the development of child psychopathology. This paper aims to explore the effects of both breastfeeding and mother-child interactions on child behavioral outcomes at a later age. Children from the China Jintan Child Cohort Study (N = 1267, at age six years old were assessed, along with their parents. Children who were breastfed exclusively for a period of time in the presence of active bonding were compared to those who were breastfed in the absence of active bonding as well as to children who were not exclusively breastfed, with or without active bonding. Results from ANOVA and GLM, using SPSS20, indicate that children who were breastfed and whose mothers actively engaged with them displayed the lowest risk of internalizing problems (mean = 10.01, SD = 7.21, while those who were neither exclusively breastfed nor exposed to active bonding had the least protection against later internalizing problems (mean = 12.79, SD = 8.14. The effect of breastfeeding on internalizing pathology likely represents a biosocial and holistic effect of physiological, and nutritive, and maternal-infant bonding benefits.

  1. International comparison of activity measurements of a solution of 75Se

    Science.gov (United States)

    Ratel, Guy

    2002-04-01

    Activity measurements of a solution of 75Se, supplied by the BIPM, have been carried out by 21 laboratories within the framework of an international comparison. Seven different methods were used. Details on source preparation, experimental facilities and counting data are reported. The measured activity-concentration values show a total spread of 6.62% before correction and 6.02% after correction for delayed events, with standard deviations of the unweighted means of 0.45% and 0.36%, respectively. The correction for delayed events was measured directly by four laboratories. Unfortunately no consensus on the activity value could be deduced from their results. The results of the comparison have been entered in the tables of the International Reference System (SIR) for γ-ray emitting radionuclides. The half-life of the metastable state was also determined by two laboratories and found to be in good agreement with the values found in the literature.

  2. Different amounts of ejaculatory activity, a natural rewarding behavior, induce differential mu and delta opioid receptor internalization in the rat's ventral tegmental area.

    Science.gov (United States)

    Garduño-Gutiérrez, René; León-Olea, Martha; Rodríguez-Manzo, Gabriela

    2013-12-06

    Opioid receptors internalize upon specific agonist stimulation. The in vivo significance of receptor internalization is not well established, partly due to the limited in vivo models used to study this phenomenon. Ejaculation promotes endogenous opioid release which activates opioid receptors at the brain, including the mesolimbic system and medial preoptic area. The objective of the present work was to analyze if there was a correlation between the degree of in vivo mu (MOR) and delta opioid receptor (DOR) internalization in the ventral tegmental area and the execution of different amounts of ejaculatory behavior of male rats. To this aim, we analyzed the brains of rats that ejaculated once or six successive times and of sexually exhausted rats with an established sexual inhibition, using immunofluorescence and confocal microscopy. Results showed that MOR and DOR internalization increased as a consequence of ejaculation. There was a relationship between the amount of sexual activity executed and the degree of internalization for MOR, but not for DOR. MOR internalization was larger in rats that ejaculated repeatedly than in animals ejaculating only once. Significant DOR internalization was found only in animals ejaculating once. Changes in MOR, DOR and beta arrestin2 detection, associated to sexual activity, were also found. It is suggested that copulation to satiety might be useful as a model system to study the biological significance of receptor internalization. © 2013 Published by Elsevier B.V.

  3. Including women in work | IDRC - International Development ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2017-06-13

    Jun 13, 2017 ... ... near the production site to limit their travel to and from work, and she designed a ... Counting Women's Work found that the time women and girls spend ... the creation of jobs based on the real needs of women and families.

  4. Validity of the international physical activity questionnaire and the Singapore prospective study program physical activity questionnaire in a multiethnic urban Asian population

    Directory of Open Access Journals (Sweden)

    Tai E Shyong

    2011-10-01

    Full Text Available Abstract Background Physical activity patterns of a population remain mostly assessed by the questionnaires. However, few physical activity questionnaires have been validated in Asian populations. We previously utilized a combination of different questionnaires to assess leisure time, transportation, occupational and household physical activity in the Singapore Prospective Study Program (SP2. The International Physical Activity Questionnaire (IPAQ has been developed for a similar purpose. In this study, we compared estimates from these two questionnaires with an objective measure of physical activity in a multi-ethnic Asian population. Methods Physical activity was measured in 152 Chinese, Malay and Asian Indian adults using an accelerometer over five consecutive days, including a weekend. Participants completed both the physical activity questionnaire in SP2 (SP2PAQ and IPAQ long form. 43subjects underwent a second set of measurements on average 6 months later to assess reproducibility of the questionnaires and the accelerometer measurements. Spearman correlations were used to evaluate validity and reproducibility and correlations for validity were corrected for within-person variation of accelerometer measurements. Agreement between the questionnaires and the accelerometer measurements was also evaluated using Bland Altman plots. Results The corrected correlation with accelerometer estimates of energy expenditure from physical activity was better for the SP2PAQ (vigorous activity: r = 0.73; moderate activity: r = 0.27 than for the IPAQ (vigorous activity: r = 0.31; moderate activity: r = 0.15. For moderate activity, the corrected correlation between SP2PAQ and the accelerometer was higher for Chinese (r = 0.38 and Malays (r = 0.57 than for Indians (r = -0.09. Both questionnaires overestimated energy expenditure from physical activity to a greater extent at higher levels of physical activity than at lower levels of physical activity. The

  5. Including Youth with Intellectual Disabilities in Health Promotion Research: Development and Reliability of a Structured Interview to Assess the Correlates of Physical Activity among Youth

    Science.gov (United States)

    Curtin, Carol; Bandini, Linda G.; Must, Aviva; Phillips, Sarah; Maslin, Melissa C. T.; Lo, Charmaine; Gleason, James M.; Fleming, Richard K.; Stanish, Heidi I.

    2016-01-01

    Background: The input of youth with intellectual disabilities in health promotion and health disparities research is essential for understanding their needs and preferences. Regular physical activity (PA) is vital for health and well-being, but levels are low in youth generally, including those with intellectual disabilities. Understanding the…

  6. Aspects of UN Activities on the International Protection of Women's Rights

    Directory of Open Access Journals (Sweden)

    Jana Maftei

    2015-05-01

    Full Text Available Human rights and their protection represent the regulation object of a major part of all the legal rules encompassing the international public law. The Members’ efforts to protect women's rights and to promote gender equality have resulted in the adoption of important documents, fundamental to all mankind. In the light of these international regulations, States have assumed obligations and they have created mechanisms to achieve them. Through the analytical approach we have highlighted the activities of the United Nations and international bodies for protecting women's rights and gender equality in all sectors of public and private life. In preparing this article we used as research methods the analysis of problems generated by the subject in question with reference to the doctrinal views expressed in the Treaties and specialized articles, documentary research, interpretation of legal norms in the field.

  7. Drilling in troubled waters. For an international regulation on offshore gas and oil activities

    International Nuclear Information System (INIS)

    Rochette, Julien

    2014-01-01

    Due to an increased energy demand, offshore activities are being extended to deep and ultra-deep waters: nearly one third of consumed oil and one quarter of consumed gas come from offshore drilling. This development threatens the environment and natural resources, and may have an impact on human activities which depend on the concerned ecosystems. As some accident had cross-border consequences, the relevance of the international regulatory framework is put into question again. This article first outlines the incomplete character of the legal framework for the safety of offshore activities: uncoordinated national systems, lack of an international convention, fragmented regional initiatives (some agreements exist for some specific regions: Arctic Sea, Baltic Sea, Mediterranean Sea, North-Eastern Atlantic, Persic Gulf and Oman Sea, Africa, western Indian Ocean). The author outlines that there is no international rules regarding responsibility and compensations. While highlighting the risks of a status-quo on these different issues, the author proposes and discusses a set of recommendations aimed at strengthening the regulation of offshore drilling activities

  8. The State Supervision (Control in the Sphere of Economic Activity: International Experience Relevant for Ukraine

    Directory of Open Access Journals (Sweden)

    Vdovychenko Larysa Yu.

    2018-01-01

    Full Text Available The attempts in the process of decentralization in Ukraine to implement the best international practices of the State supervision (control in the sphere of economic activity, in the process which depends on the status of deregulation and development of entrepreneurship, have caused the topicality of the problem set. The article is aimed at analyzing the international experience of application of the State supervision (control instruments in the sphere of economic activity and determination of the directions of their use in Ukraine. The stages of reforms of the control and supervision activity both in foreign countries and in Ukraine were considered. The directions and measures on creation of effective system of the State supervision (control in the sphere of economic activity, applied in the world countries, were systematized. Both the positive and the negative aspects of use of foreign instruments of the State supervision (control in the sphere of economic activity in Ukraine have been defined. Recommendations on formation of the national complex system of functioning of control-supervision activity have been given.

  9. Incorporating International Business Topics into Every Class.

    Science.gov (United States)

    Perreault, Heidi; Burchfield, Kathy

    2001-01-01

    Presents activities and resources for addressing international business in the curriculum, including e-mail partnerships, international document specifications, currency comparisons, marketing to other cultures, scavenger hunt, business lunch, and international telephone and travel etiquette. (SK)

  10. International Physical Activity Questionnaire (IPAQ and New Zealand Physical Activity Questionnaire (NZPAQ: A doubly labelled water validation

    Directory of Open Access Journals (Sweden)

    Rodgers Anthony

    2007-12-01

    Full Text Available Abstract Background Accurate measurement of physical activity is a pre-requisite for monitoring population health and for evaluating effective interventions. The International Physical Activity Questionnaire (IPAQ is used as a comparable and standardised self-report measure of habitual physical activity of populations from different countries and socio-cultural contexts. The IPAQ has been modified to produce a New Zealand physical activity questionnaire (NZPAQ. The aim of this study was to validate the IPAQ and NZPAQ against doubly labelled water (DLW. Method: Total energy expenditure (TEE was measured over a 15-day period using DLW. Activity-related energy expenditure (AEE was estimated by subtracting the energy expenditure from resting metabolic rate and thermic effect of feeding from TEE. The IPAQ (long form and NZPAQ (short form were completed at the end of each 7-day period. Activity-related energy expenditure (IPAQAEE and NZPAQAEE was calculated from each questionnaire and compared to DLWAEE. Results Thirty six adults aged 18 to 56 years (56% female completed all measurements. Compared to DLWAEE, IPAQAEE and NZPAQAEE on average underestimated energy expenditure by 27% and 59%, respectively. There was good agreement between DLWAEE and both IPAQAEE and NZPAQAEE at lower levels of physical activity. However there was marked underestimation of questionnaire-derived energy expenditure at higher levels of activity. Conclusion Both the IPAQ and NZPAQ instruments have a demonstrated systematic bias toward underestimation of physical activity-related energy expenditure at higher levels of physical activity compared to DLW. Appropriate calibration factors could be used to correct for measurement error in physical activity questionnaires and hence improve estimation of AEE.

  11. Activities of the IAEA International Working Group on Life Management of Nuclear Power Plants (IWG-LMNPP)

    International Nuclear Information System (INIS)

    Ianko, L.

    1994-01-01

    Activities of the IAEA international working group on life management of nuclear power plants are outlined with emphasis on objectives, scope of activities, methods of work, organizational matters, financing

  12. Precise shape reconstruction by active pattern in total-internal-reflection-based tactile sensor.

    Science.gov (United States)

    Saga, Satoshi; Taira, Ryosuke; Deguchi, Koichiro

    2014-03-01

    We are developing a total-internal-reflection-based tactile sensor in which the shape is reconstructed using an optical reflection. This sensor consists of silicone rubber, an image pattern, and a camera. It reconstructs the shape of the sensor surface from an image of a pattern reflected at the inner sensor surface by total internal reflection. In this study, we propose precise real-time reconstruction by employing an optimization method. Furthermore, we propose to use active patterns. Deformation of the reflection image causes reconstruction errors. By controlling the image pattern, the sensor reconstructs the surface deformation more precisely. We implement the proposed optimization and active-pattern-based reconstruction methods in a reflection-based tactile sensor, and perform reconstruction experiments using the system. A precise deformation experiment confirms the linearity and precision of the reconstruction.

  13. Report on the Status of the SFWST Campaign International Activities in Disposal Research at SNL

    Energy Technology Data Exchange (ETDEWEB)

    McMahon, Kevin A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Nuclear Waste Disposal Research and Analysis. New Mexico Energy and Geoscience Center

    2017-08-22

    The following summaries are provided as fulfillment of milestone M4SF-17SN080305022 and represent international coordination activities in disposal research funded by the US DOE Spent Fuel and Waste Storage and Technologies (SFWST) Campaign during Fiscal Year 2017: SFWST funded bi-lateral interactions with Taiwan, OECD-NEA Repository Metadata (RepMet) project, SFWST funded bi-lateral interactions with the Republic of Korea.

  14. Validity and Reliability of International Physical Activity Questionnaire-Short Form in Chinese Youth

    Science.gov (United States)

    Wang, Chao; Chen, Peijie; Zhuang, Jie

    2013-01-01

    Purpose: The psychometric profiles of the widely used International Physical Activity Questionnaire-Short Form (IPAQ-SF) in Chinese youth have not been reported. The purpose of this study was to examine the validity and reliability of the IPAQ-SF using a sample of Chinese youth. Method: One thousand and twenty-one youth (M[subscript age] = 14.26 ±…

  15. International Active Surveillance Study of Women Taking Oral Contraceptives (INAS-OC Study)

    OpenAIRE

    Dinger, Juergen C; Bardenheuer, Kristina; Assmann, Anita

    2009-01-01

    Abstract Background A 24-day regimen of contraceptive doses of drospirenone and ethinylestradiol (DRSP/EE 24d) was recently launched. This regimen has properties which may be beneficial for certain user populations (e.g., women suffering from premenstrual dysphoric disorder or acne). However, it is unknown whether this extended regimen has an impact on the cardiovascular risk associated with the use of oral contraceptives (OCs). The INternational Active Surveillance study of women taking Oral...

  16. Activating institutional innovations for hunger and poverty reduction : potential of applied international agricultural research

    OpenAIRE

    Kamanda, Josey

    2015-01-01

    The CGIAR system has made several attempts to improve its organizational structure, the latest being a reform process initiated in 2009. A key issue that has been debated over the years is how the CGIAR centres are best placed within the range of institutions involved in agricultural research and development. The CGIAR still faces the unresolved dilemma between a focus on upstream research that produces international public goods versus downstream activities that ensure impact. Therefore, the...

  17. Radon variations in active volcanoes and in regions with high seismicity: internal and external factors

    International Nuclear Information System (INIS)

    Segovia, N.; Cruz-Reyna, S. De la; Mena, M.

    1986-01-01

    The results of 4 years of observations of radon concentrations in soils of active volcanoes of Costa Rica and a highly seismic region in Mexico are discussed. A distinction is made between the influences of external (mostly meteorological) and internal (magmatic or tectonic) factors on the variation in radon levels. The geological meaning of the radon data can be thus enhanced if the external factors are excluded. (author)

  18. Towards better description of solar activity variation in the International Reference Ionosphere topside ion composition model

    Czech Academy of Sciences Publication Activity Database

    Truhlík, Vladimír; Bilitza, D.; Třísková, Ludmila

    2015-01-01

    Roč. 55, č. 8 (2015), s. 2099-2105 ISSN 0273-1177 R&D Projects: GA MŠk(CZ) LH11123 Institutional support: RVO:68378289 Keywords : ion composition * topside ionosphere * solar activity * empirical model * International Reference Ionosphere Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 1.409, year: 2015 http://www.sciencedirect.com/science/article/pii/S027311771400489X

  19. Internal consistency of the CHAMPS physical activity questionnaire for Spanish speaking older adults.

    Science.gov (United States)

    Rosario, Martín G; Vázquez, Jenniffer M; Cruz, Wanda I; Ortiz, Alexis

    2008-09-01

    The Community Healthy Activities Model Program for Seniors (CHAMPS) is a physical activity monitoring questionnaire for people between 65 to 90 years old. This questionnaire has been previously translated to Spanish to be used in the Latin American population. To adapt the Spanish version of the CHAMPS questionnaire to Puerto Rico and assess its internal consistency. An external review committee adapted the existent Spanish version of the CHAMPS to be used in the Puerto Rican population. Three older adults participated in a second phase with the purpose of training the research team. After the second phase, 35 older adults participated in a third content adaptation phase. During the third phase, the preliminary Spanish version for Puerto Rico of the CHAMPS was given to the 35 participants to assess for clarity, vocabulary and understandability. Interviews to each participant in the third phase were carried out to obtain feedback and create a final Spanish version of the CHAMPS for Puerto Rico. After analyses of this phase, the external review committee prepared a final Spanish version of the CHAMPS for Puerto Rico. The final version was administered to 15 older adults (76 +/- 6.5 years) to assess the internal consistency by using Cronbach's Alpha analysis. The questionnaire showed a strong internal consistency of 0.76. The total time to answer the questionnaire was 17.4 minutes. The Spanish version of the CHAMPS questionnaire for Puerto Rico suggested being an easy to administer and consistent measurement tool to assess physical activity in older adults.

  20. Three typical examples of activation of the international charter space and major disasters

    Science.gov (United States)

    Bessis, J.; Bequignon, J.; Mahmood, A.

    The purpose of the International Charter is to provide a unified system of space data acquisition and delivery for users affected by disasters, to promote co - operation between space agencies and space system operators and to allow participation in the organisation of emergency assistance or subsequent operations. The Charter which is officially in operation since November 1, 2000 was signed on June 20, 2000 by CNES (1) and ESA (2) and enlarged later on with the membership of the CSA (3) in October 2000 and of the NOAA (4) and the ISRO (5), both in September 2001. All Partner agencies undertake to co-operate on a voluntary basis with no exchange of funds between them in the event of a major natural or man-induced disaster. This paper, after a brief description of the Charter organisation and of its implementation procedures, addresses three typical cases of Charter activation and the lessons learned to date. The first example will deal with the major earthquakes in January and February 2001 in El Salvador for the benefit of the Salvadorian National Register Centre, the second concerning flooding in the North East of France early 2002 with quick delivery of flood maps to the French Civil Protection Authority and the last one will focus on the Nyiragongo volcanic eruption near the town of Goma in the Democratic Republic of Congo. It will include feedback from the Authorised Users concerning the usefulness of the Charter and the suggested improvements in terms of response time, sensors capability and resolution, delivered products (scale and ease of operational utilisation) and adapted scenarios.(1) Centre National d'Etudes Spatiales, (2) European Space Agency, (3) Canadian Space Agency, (4) National Oceanic and Atmospheric Administration , (5) Indian Space Research Organisation

  1. CSNI activities in knowledge management and knowledge transfer - An international dimension

    International Nuclear Information System (INIS)

    Reig, J.; Hrehor, M.

    2004-01-01

    The Committee on the Safety of Nuclear Installations (CSNI) of the OECD Nuclear Energy Agency (NEA) was set up in 1973 to develop and to co-ordinate the activities of the NEA concerning the technical aspects of the design, construction and operation of nuclear installations insofar as they affect the safety of such installations. Although there is currently no formal 'CSNI knowledge management strategy', i.e. defined CSNI approach and the appropriate resources for activities related to knowledge management as such, the CSNI has been actively involved during its 30 years of existence in a number of areas closely linked with knowledge management. The paper gives a number of specific examples of various CSNI activities which, all together, represent from an international perspective a significant contribution to knowledge management efforts at the national level of the OECD/NEA member countries. (author)

  2. International conference on lessons learned from the decommissioning of nuclear facilities and the safe termination of nuclear activities. Contributed papers

    International Nuclear Information System (INIS)

    2006-12-01

    The International Atomic Energy Agency (IAEA), in cooperation with the European Commission (EC), Nuclear Energy Agency to the Organisation for Economic Co-operation and Development (OECD/NEA), and the World Nuclear Association (WNA), organized an International Conference on Lessons Learned from the Decommissioning of Nuclear Facilities and the Safe Termination of Nuclear Activities from 11 to 15 December 2006 in Athens, Greece. This Book of Contributed Papers contains technical papers and posters contributed by experts from operating organisations, regulatory bodies, technical support organisations, and other institutions on issues falling within the scope of the Conference. The following main topics were covered: Evolution of national and international policies and criteria for the safe and efficient decommissioning of nuclear facilities and safe termination of nuclear activities; Review of lessons learned from ongoing or completed activities associated with decommissioning; Improvement of safety and efficiency through the use of new and innovative technologies; Practical aspects in the management of material, waste and sites resulting from decommissioning, including the management of waste in the absence of repositories and waste acceptance requirements; Procedures for demonstrating compliance with clearance criteria; Experience from radiological assessments associated with decommissioning; Involvement of the local communities and the impact that decommissioning activities has on them. The presented papers and posters were reviewed and accepted following the guidelines established by the Conference Programme Committee for consideration at the Conference. The material compiled in this Book of Contributed Papers has not undergone rigorous editing by the editorial staff of the IAEA. However, certain modifications were made: a unified format was adopted for all papers; and minor corrections were made in the text where required. Each paper and poster has been indexed

  3. International conference on lessons learned from the decommissioning of nuclear facilities and the safe termination of nuclear activities. Contributed papers

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-12-15

    The International Atomic Energy Agency (IAEA), in cooperation with the European Commission (EC), Nuclear Energy Agency to the Organisation for Economic Co-operation and Development (OECD/NEA), and the World Nuclear Association (WNA), organized an International Conference on Lessons Learned from the Decommissioning of Nuclear Facilities and the Safe Termination of Nuclear Activities from 11 to 15 December 2006 in Athens, Greece. This Book of Contributed Papers contains technical papers and posters contributed by experts from operating organisations, regulatory bodies, technical support organisations, and other institutions on issues falling within the scope of the Conference. The following main topics were covered: Evolution of national and international policies and criteria for the safe and efficient decommissioning of nuclear facilities and safe termination of nuclear activities; Review of lessons learned from ongoing or completed activities associated with decommissioning; Improvement of safety and efficiency through the use of new and innovative technologies; Practical aspects in the management of material, waste and sites resulting from decommissioning, including the management of waste in the absence of repositories and waste acceptance requirements; Procedures for demonstrating compliance with clearance criteria; Experience from radiological assessments associated with decommissioning; Involvement of the local communities and the impact that decommissioning activities has on them. The presented papers and posters were reviewed and accepted following the guidelines established by the Conference Programme Committee for consideration at the Conference. The material compiled in this Book of Contributed Papers has not undergone rigorous editing by the editorial staff of the IAEA. However, certain modifications were made: a unified format was adopted for all papers; and minor corrections were made in the text where required. Each paper and poster has been indexed

  4. Update of the BIPM.RI(II)-K1.Tc-99m comparison of activity measurements for the radionuclide {sup 99m}Tc to include new results for the LNE-LNHB and the NPL

    Energy Technology Data Exchange (ETDEWEB)

    Michotte, C.; Courte, S.; Ratel, G. [Bureau International des Poids et Mesures (BIPM), 92 - Sevres (France); Moune, M. [LNE-LNHB, Laboratoire national de metrologie et d' essais-Laboratoire National Henri Becquerel, Gif sur Yvette (France); Johansson, L.; Keightley, J. [National Physical Laboratory (NPL), Middlesex (United Kingdom)

    2010-12-15

    In 2007 and 2008 respectively, the Laboratoire national de metrologie et d'essais -Laboratoire national Henri Becquerel (LNE-LNHB), France and the National Physical Laboratory (NPL), UK, submitted ampoules with between 10 MBq and 130 MBq activity of {sup 99m}Tc to the International Reference System (SIR), to update their results in the BIPM.RI(II)-K1.Tc-99m comparison. Together with the four other national metrology institutes (NMI) that are participants, thirteen samples have been submitted since 1983. The key comparison reference value (KCRV) has been recalculated to include the latest primary results of the PTB and the LNE-LNB as this makes the evaluation more robust. The degrees of equivalence between each equivalent activity measured in the SIR are given in the form of a matrix for all six NMIs. A graphical presentation is also given. (authors)

  5. People who perceive themselves as active cannot identify the intensity recommended by the international physical activity guidelines

    Directory of Open Access Journals (Sweden)

    Prokop NW

    2014-10-01

    Full Text Available Neal W Prokop,1 Travis JR Hrubeniuk,1 Martin Sénéchal,2,3 Danielle R Bouchard1,4 1Faculty of Kinesiology and Recreation Management, University of Manitoba, Winnipeg, Manitoba, Canada; 2Manitoba Institute of Child Health, Winnipeg, Manitoba, Canada; 3Department of Pediatrics and Child Health, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada; 4Health, Leisure, and Human Performance Research Institute, Winnipeg, Manitoba, Canada Background: Many national and international organizations recommend that adults achieve at least 150 minutes of aerobic physical activity (PA weekly, at a minimum moderate intensity to optimize health benefits. It is unknown if people who consider themselves as active have the ability to identify what is considered moderate intensity. Methods: Fifty-one participants who reported achieving a minimum 150 minutes per week at a minimum of moderate intensity PA were recruited through a local fitness facility. All participants underwent a single assessment involving questionnaires, clinical measures, and a treadmill test to measure the ability to perceive moderate intensity. Following the visit, participants' PA level was evaluated by heart rate monitor, while exercising, for 7 consecutive days. Results: Eighty percent of participants overestimated moderate intensity on the treadmill test; they were at vigorous intensity compared to what is considered moderate. Only 11.8% of participants accurately identified moderate intensity; all of them were women (P=0.03, had a high level of education (P=0.04, and knew that moderate intensity was the minimum intensity recommended by health organizations (P<0.01. Only 69.2% of participants reached the aerobic component of the International Physical Activity Guidelines with no significant advantage for those correctly identifying moderate intensity. Conclusion: Most people who perceive themselves as active are exercising at vigorous intensity while believing they are

  6. THE EFFECT OF BUSINESS FIRMS’ INTERNATIONAL ACTIVITIES ON THE FIRM PERFORMANCE: A CENTRAL BLACK SEA REGION CASE

    Directory of Open Access Journals (Sweden)

    Erkut ALTINDAG

    2014-04-01

    Full Text Available In this study, the effect of business firms carrying on business in Central Black Sea Region of Turkey on the performance of these firms. Especially how it affected SMEs (Small and Medium Sized Enterprises was analyzed. When particularly considering the effects of business that have SME quality on economy of Turkey, such kind of researches are noticed to have a basis in recent years. The research depended upon the data obtained from enterprises through original qualified questionnaire. The questionnaire question forms were scaled benefiting from the studies in the literature based upon international activities and business performance measurement. For all variables, the scales in the literature were taken and included into research questionnaire. The questionnaires were performed to SMEs and large-scale enterprises. In the research factor analysis, correlation and regression analysis were included as analysis methods. According to the obtained results, it was determined that international activities had a positive effect on the performance of enterprises. The results were interpreted, and various suggestions were offered to academicians, and administrators.

  7. Photon activation analysis using internal standards: some studies of the analysis of environmental materials

    Energy Technology Data Exchange (ETDEWEB)

    Masumoto, K; Yagi, M

    1986-01-01

    The authors report the application of the internal standard method to the simultaneous determination of trace elements in environmental reference materials. The standard soil material used was IAEA CRM Soil-5. The power plant fly ash reference used was NBS SRM-1633a. Fifteen target elements, including As, Ba and Ce, were determined. Internal standards were supplied by six elements, including Na and Mg. Although there were several interfering elements, their effect could be eliminated by utilizing more than one gamma-ray peak and carrying out appropriate corrections. The values determined for most of the target elements were well within the certified range. Measured concentrations were of the orders of 10 to 1000 ..mu..g/g. 6 references, 2 figures, 5 tables.

  8. Activities and future plans of the international commission on non-ionizing radiation protection (ICNIRP)

    International Nuclear Information System (INIS)

    Bernhardt, J.H.

    2000-01-01

    , on Risk perception and communication and on EMF impact on the Environment have been jointly organised. In collaboration with the European Commission an expert group elaborated a proposal for research on possible health effects of RF fields, emitted by mobile telephones, which is now included in the Framework V-Programme. European ICNIRP members have given advice to the DG V concerning the public exposure to EMF. The result was a Council Recommendation on limiting exposure of the general public to electromagnetic fields, based on ICNIRP's EMF guidelines, which was approved last summer. One of the most important issues will be the work on reviews of the biological and health effects of static and ELF-Fields (this work started in 1998), on radiofrequency fields and on optical radiation. The reviews will contain a detailed health risk assessment and can be used from WHO and IARC for the revision of WHO's Health Criteria documents. Other issues will be the revision of the guidelines on UV-radiation, on Airbome Ultrasound and on EMF. The statements on UV-sunbeds and on the Use of Magnetic Resonance methods will be revised. One important issue is - in collaboration with WHO - the process of an International Harmonisation of EMF standards. One problem of the Commission are financial subsidies. ICNIRP owes great gratitude to the German Ministry of Environment for providing resources to maintain the ICNIRP secretariat and to IRPA and WHO for grants that allow ICNIRP to continue its independent activities. Unfortunately, the EU stopped its funding in 1998, so that ICNIRP has to look for other sources of funding. (author)

  9. Loss of Proliferation and Antigen Presentation Activity following Internalization of Polydispersed Carbon Nanotubes by Primary Lung Epithelial Cells

    Science.gov (United States)

    Kumari, Mandavi; Sachar, Sumedha; Saxena, Rajiv K.

    2012-01-01

    Interactions between poly-dispersed acid functionalized single walled carbon nanotubes (AF-SWCNTs) and primary lung epithelial (PLE) cells were studied. Peritoneal macrophages (PMs, known phagocytic cells) were used as positive controls in this study. Recovery of live cells from cultures of PLE cells and PMs was significantly reduced in the presence of AF-SWCNTs, in a time and dose dependent manner. Both PLE cells as well as PMs could take up fluorescence tagged AF-SWCNTs in a time dependent manner and this uptake was significantly blocked by cytochalasin D, an agent that blocks the activity of acto-myosin fibers and therefore the phagocytic activity of cells. Confocal microscopic studies confirmed that AF-SWCNTs were internalized by both PLE cells and PMs. Intra-trachially instilled AF-SWCNTs could also be taken up by lung epithelial cells as well as alveolar macrophages. Freshly isolated PLE cells had significant cell division activity and cell cycling studies indicated that treatment with AF-SWCNTs resulted in a marked reduction in S-phase of the cell cycle. In a previously standardized system to study BCG antigen presentation by PLE cells and PMs to sensitized T helper cells, AF-SWCNTs could significantly lower the antigen presentation ability of both cell types. These results show that mouse primary lung epithelial cells can efficiently internalize AF-SWCNTs and the uptake of nanotubes interfered with biological functions of PLE cells including their ability to present BCG antigens to sensitized T helper cells. PMID:22384094

  10. The International Gravity Field Service (IGFS): Present Day Activities And Future Plans

    Science.gov (United States)

    Barzaghi, R.; Vergos, G. S.

    2016-12-01

    IGFS is a unified "umbrella" IAG service that coordinates the servicing of the geodetic and geophysical community with gravity field related data, software and information. The combined data of the IGFS entities will include global geopotential models, terrestrial, airborne, satellite and marine gravity observations, Earth tide data, GPS/levelling data, digital models of terrain and bathymetry, as well as ocean gravity field and geoid from satellite altimetry. The IGFS structure is based on the Gravity Services, the "operating arms" of IGFS. These Services related to IGFS are: BGI (Bureau Gravimetrique International), Toulouse, France ISG (International Service for the Geoid), Politecnico di Milano, Milano, Italy IGETS (International Geodynamics and Earth Tides Service), EOST, Strasbourg, France ICGEM (International Center for Global Earth Models), GFZ, Potsdam, Germany IDEMS (International Digital Elevation Model Service), ESRI, Redlands, CA, USA The Central Bureau, hosted at the Aristotle Thessaloniki University, is in charge for all the interactions among the services and the other IAG bodies, particularly GGOS. In this respect, connections with the GGOS Bureaus of Products and Standards and of Networks and Observations have been recently strengthened in order to align the Gravity services to the GGOS standards. IGFS is also strongly involved in the most relevant projects related to the gravity field such as the establishment of the new Global Absolute Gravity Reference System and of the International Height Reference System. These projects, along with the organization of Geoid Schools devoted to methods for gravity and geoid estimate, will play a central role in the IGFS future actions in the framework of GGOS.

  11. Non-linear Relationship between BOLD Activation and Amplitude of Beta Oscillations in the Supplementary Motor Area during Rhythmic Finger Tapping and Internal Timing

    Science.gov (United States)

    Gompf, Florian; Pflug, Anja; Laufs, Helmut; Kell, Christian A.

    2017-01-01

    Functional imaging studies using BOLD contrasts have consistently reported activation of the supplementary motor area (SMA) both during motor and internal timing tasks. Opposing findings, however, have been shown for the modulation of beta oscillations in the SMA. While movement suppresses beta oscillations in the SMA, motor and non-motor tasks that rely on internal timing increase the amplitude of beta oscillations in the SMA. These independent observations suggest that the relationship between beta oscillations and BOLD activation is more complex than previously thought. Here we set out to investigate this rapport by examining beta oscillations in the SMA during movement with varying degrees of internal timing demands. In a simultaneous EEG-fMRI experiment, 20 healthy right-handed subjects performed an auditory-paced finger-tapping task. Internal timing was operationalized by including conditions with taps on every fourth auditory beat, which necessitates generation of a slow internal rhythm, while tapping to every auditory beat reflected simple auditory-motor synchronization. In the SMA, BOLD activity increased and power in both the low and the high beta band decreased expectedly during each condition compared to baseline. Internal timing was associated with a reduced desynchronization of low beta oscillations compared to conditions without internal timing demands. In parallel with this relative beta power increase, internal timing activated the SMA more strongly in terms of BOLD. This documents a task-dependent non-linear relationship between BOLD and beta-oscillations in the SMA. We discuss different roles of beta synchronization and desynchronization in active processing within the same cortical region. PMID:29249950

  12. Non-linear Relationship between BOLD Activation and Amplitude of Beta Oscillations in the Supplementary Motor Area during Rhythmic Finger Tapping and Internal Timing.

    Science.gov (United States)

    Gompf, Florian; Pflug, Anja; Laufs, Helmut; Kell, Christian A

    2017-01-01

    Functional imaging studies using BOLD contrasts have consistently reported activation of the supplementary motor area (SMA) both during motor and internal timing tasks. Opposing findings, however, have been shown for the modulation of beta oscillations in the SMA. While movement suppresses beta oscillations in the SMA, motor and non-motor tasks that rely on internal timing increase the amplitude of beta oscillations in the SMA. These independent observations suggest that the relationship between beta oscillations and BOLD activation is more complex than previously thought. Here we set out to investigate this rapport by examining beta oscillations in the SMA during movement with varying degrees of internal timing demands. In a simultaneous EEG-fMRI experiment, 20 healthy right-handed subjects performed an auditory-paced finger-tapping task. Internal timing was operationalized by including conditions with taps on every fourth auditory beat, which necessitates generation of a slow internal rhythm, while tapping to every auditory beat reflected simple auditory-motor synchronization. In the SMA, BOLD activity increased and power in both the low and the high beta band decreased expectedly during each condition compared to baseline. Internal timing was associated with a reduced desynchronization of low beta oscillations compared to conditions without internal timing demands. In parallel with this relative beta power increase, internal timing activated the SMA more strongly in terms of BOLD. This documents a task-dependent non-linear relationship between BOLD and beta-oscillations in the SMA. We discuss different roles of beta synchronization and desynchronization in active processing within the same cortical region.

  13. Water permeation through the internal water pathway in activated GPCR rhodopsin.

    Directory of Open Access Journals (Sweden)

    Katsufumi Tomobe

    Full Text Available Rhodopsin is a light-driven G-protein-coupled receptor that mediates signal transduction in eyes. Internal water molecules mediate activation of the receptor in a rhodopsin cascade reaction and contribute to conformational stability of the receptor. However, it remains unclear how internal water molecules exchange between the bulk and protein inside, in particular through a putative solvent pore on the cytoplasmic. Using all-atom molecular dynamics simulations, we identified the solvent pore on cytoplasmic side in both the Meta II state and the Opsin. On the other hand, the solvent pore does not exist in the dark-adapted rhodopsin. We revealed two characteristic narrow regions located within the solvent pore in the Meta II state. The narrow regions distinguish bulk and the internal hydration sites, one of which is adjacent to the conserved structural motif "NPxxY". Water molecules in the solvent pore diffuse by pushing or sometimes jumping a preceding water molecule due to the geometry of the solvent pore. These findings revealed a total water flux between the bulk and the protein inside in the Meta II state, and suggested that these pathways provide water molecules to the crucial sites of the activated rhodopsin.

  14. Objectively measured physical activity and sedentary time in youth: the International children's accelerometry database (ICAD).

    Science.gov (United States)

    Cooper, Ashley R; Goodman, Anna; Page, Angie S; Sherar, Lauren B; Esliger, Dale W; van Sluijs, Esther M F; Andersen, Lars Bo; Anderssen, Sigmund; Cardon, Greet; Davey, Rachel; Froberg, Karsten; Hallal, Pedro; Janz, Kathleen F; Kordas, Katarzyna; Kreimler, Susi; Pate, Russ R; Puder, Jardena J; Reilly, John J; Salmon, Jo; Sardinha, Luis B; Timperio, Anna; Ekelund, Ulf

    2015-09-17

    Physical activity and sedentary behaviour in youth have been reported to vary by sex, age, weight status and country. However, supporting data are often self-reported and/or do not encompass a wide range of ages or geographical locations. This study aimed to describe objectively-measured physical activity and sedentary time patterns in youth. The International Children's Accelerometry Database (ICAD) consists of ActiGraph accelerometer data from 20 studies in ten countries, processed using common data reduction procedures. Analyses were conducted on 27,637 participants (2.8-18.4 years) who provided at least three days of valid accelerometer data. Linear regression was used to examine associations between age, sex, weight status, country and physical activity outcomes. Boys were less sedentary and more active than girls at all ages. After 5 years of age there was an average cross-sectional decrease of 4.2% in total physical activity with each additional year of age, due mainly to lower levels of light-intensity physical activity and greater time spent sedentary. Physical activity did not differ by weight status in the youngest children, but from age seven onwards, overweight/obese participants were less active than their normal weight counterparts. Physical activity varied between samples from different countries, with a 15-20% difference between the highest and lowest countries at age 9-10 and a 26-28% difference at age 12-13. Physical activity differed between samples from different countries, but the associations between demographic characteristics and physical activity were consistently observed. Further research is needed to explore environmental and sociocultural explanations for these differences.

  15. Climate modulates internal wave activity in the Northern South China Sea

    Science.gov (United States)

    DeCarlo, Thomas M.; Karnauskas, Kristopher B.; Davis, Kristen A.; Wong, George T. F.

    2015-02-01

    Internal waves (IWs) generated in the Luzon Strait propagate into the Northern South China Sea (NSCS), enhancing biological productivity and affecting coral reefs by modulating nutrient concentrations and temperature. Here we use a state-of-the-art ocean data assimilation system to reconstruct water column stratification in the Luzon Strait as a proxy for IW activity in the NSCS and diagnose mechanisms for its variability. Interannual variability of stratification is driven by intrusions of the Kuroshio Current into the Luzon Strait and freshwater fluxes associated with the El Niño-Southern Oscillation. Warming in the upper 100 m of the ocean caused a trend of increasing IW activity since 1900, consistent with global climate model experiments that show stratification in the Luzon Strait increases in response to radiative forcing. IW activity is expected to increase in the NSCS through the 21st century, with implications for mitigating climate change impacts on coastal ecosystems.

  16. Joint study on activation of international nuclear information use through implementation INIS DB server with IAEA

    International Nuclear Information System (INIS)

    Lee, H. C.; Yi, J. H.; Kim, T. W.; Chun, Y. C.; Yoo, A. N.

    2003-03-01

    In order to install the INIS DB host site in Korea, the Korea INIS national center has cooperated with KAERI and organizations concerned, contacted the INIS secretariat participated in the consultative meeting of INIS liaison officers, and strengthened the relationship with Asian and Oceanian countries. And KAERI staff and a maintenance engineer participated training seminar on INIS DB installation and maintenance. The Korea national center obtained the INIS DB server code and data by international cooperation activity. Based these code and data, hardware and software for INIS DB server are purchased. INIS DB server system was installed the software and INIS database(2,347,302) was constructed. In 2003 INIS host DB site started to provide web service in Korea. Also It enables the users in the member countries in Asia as well as domestic users to get quick information. It will also bring the active use of the domestic INIS DB and the increase of the productivity of domestic research activities

  17. Using internal coupling activities to enhance the effectiveness of open innovation

    DEFF Research Database (Denmark)

    Burcharth, Ana Luiza de Araújo; Knudsen, Mette Præst; Søndergaard, Helle Alsted

    This paper investigates the role of specific intra-organizational mechanisms in analyzing performance implications of openness by addressing two questions: does openness to innovation influence innovation performance? And if so, what organizational activities facilitate increased effectiveness...... of both inbound and outbound open innovation practices? The paper identifies a set of internal management mechanisms that allows the firm to couple the outside-in and inside-out knowledge flows in support of integrating external knowledge and internal competencies. The empirical basis of the study...... is a survey carried out in 321 Danish SMEs in manufacturing industries. The paper cannot substantiate the thus far, seemingly positive evidence of openness on innovation performance. Rather, the paper finds that inbound open innovation is related to the introduction of new products, whereas the adoption...

  18. An overview of the International Electrotechnical Commission's activities on quality assurance in diagnostic radiology

    International Nuclear Information System (INIS)

    Julius, H.W.; Ammers, H. van; Henshaw, E.T.

    1989-01-01

    In 1981, the International Electrotechnical Commission Sub-committee 62B set up a Working Group to deal with quality assurance in diagnostic X-ray departments and, more specifically, to develop international standards describing procedures to test the constancy of parameters of diagnostic X-ray Departments, four draft standards on specific topics, seven more documents are in advanced stage, and several others under consideration. According to the approach adopted by the Working Group, these documents are meant to assist in establishing quality assurance programmes in hospitals and provide guidance on how to perform tests and interpret results. This paper reveals the general philosophy behind the activities of the Working Group as well as some details of the standards produced so far, with emphasis on physical parameters of diagnostic X-ray installations and proposed criteria for satisfactory performance. (author)

  19. [Antibacterial actin of vinegar against food-borne pathogenic bacteria including Escherichia coli O157:H7 (Part 2). Effect of sodium chloride and temperature on bactericidal activity].

    Science.gov (United States)

    Entani, E; Asai, M; Tsujihata, S; Tsukamoto, Y; Ohta, M

    1997-05-01

    Bactericidal effects of various kinds of AWASEZU (processed vinegar, 2.5% acidity) on food-borne pathogenic bacteria including Escherichia coli O157:H7 and other bacteria were examined. the order of bactericidal activities was NIHAIZU (3.5% NaCl was added) > SANBA-IZU (3.5% NaCl and 10% sucrose were added) > plain vinegar (spirit vinegar) > AMAZU (10% sucrose was added). This indicates that their activities were enhanced by the addition of sodium chloride and suppressed by the addition of sugar. On the other hand, when soy sauce was used instead of sodium chloride, the order of bactericidal activities was plain vinegar > AMAZU > NIHAIZU > SANBAIZU. This is mainly because their activities were suppressed by the increase in the pH value. The effect of sodium chloride (0.01-15%) and temperature (10-50 degrees C) on bactericidal activities against E. coli O157:H7 in spirit vinegar (0.5-2.5% acidity) was further examined. When vinegar was used in combination with sodium chloride, predominant synergism on the bactericidal activity was observed. Their activities were markedly enhanced by the addition of sodium chloride in proportion to the concentration. In addition to this, at higher temperatures spirit vinegar killed bacteria much more rapidly. It should be noted that the bactericidal activity of spirit vinegar was extremely enhanced by the combined use of the addition of sodium chloride and the rise of temperature. For example, in 2.5% acidity vinegar, the time required for 3 log decrease in viable cell numbers at 20 degrees C was shortened to 1/140-fold by the addition of 5% sodium chloride, shortened to 1/51-fold by the rise of the reaction temperature at 40 degrees C, and shortened to 1/830-fold; 0.89 minutes by both the addition of 5% sodium chloride and the rise of temperature at 40 degrees C. In order to propose the methods to prevent food poisoning by bacterial infection, bactericidal activities of vinegar solution containing sodium chloride on cooking tools and

  20. Oak Ridge National Laboratory Office of International Nuclear Safeguards: Human Capital Development Activity in FY16

    International Nuclear Information System (INIS)

    Gilligan, Kimberly V.; Gaudet, Rachel N.

    2016-01-01

    In 2007, the U.S. Department of Energy National Nuclear Security Administration (DOE NNSA) Office of Nonproliferation and Arms Control (NPAC) completed a comprehensive review of the current and potential future challenges facing the international safeguards system. One of the report's key recommendations was for DOE NNSA to launch a major new program to revitalize the international safeguards technology and human resource base. In 2007, at the International Atomic Energy Agency (IAEA) General Conference, then Secretary of Energy Samuel W. Bodman announced the newly created Next Generation Safeguards Initiative (NGSI). NGSI consists of five program elements: policy development and outreach, concepts and approaches, technology and analytical methodologies, human capital development (HCD), and infrastructure development. This report addresses the HCD component of NGSI. The goal of the HCD component as defined in the NNSA Program Plan is ''to revitalize and expand the international safeguards human capital base by attracting and training a new generation of talent.'' The major objectives listed in the HCD goal include education and training, outreach to universities and professional societies, postdoctoral appointments, and summer internships at national laboratories.

  1. Oak Ridge National Laboratory Office of International Nuclear Safeguards: Human Capital Development Activity in FY16

    Energy Technology Data Exchange (ETDEWEB)

    Gilligan, Kimberly V. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Nuclear Security and Isotope Technology Division; Gaudet, Rachel N. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Nuclear Security and Isotope Technology Division

    2016-09-30

    In 2007, the U.S. Department of Energy National Nuclear Security Administration (DOE NNSA) Office of Nonproliferation and Arms Control (NPAC) completed a comprehensive review of the current and potential future challenges facing the international safeguards system. One of the report’s key recommendations was for DOE NNSA to launch a major new program to revitalize the international safeguards technology and human resource base. In 2007, at the International Atomic Energy Agency (IAEA) General Conference, then Secretary of Energy Samuel W. Bodman announced the newly created Next Generation Safeguards Initiative (NGSI). NGSI consists of five program elements: policy development and outreach, concepts and approaches, technology and analytical methodologies, human capital development (HCD), and infrastructure development. This report addresses the HCD component of NGSI. The goal of the HCD component as defined in the NNSA Program Plan is “to revitalize and expand the international safeguards human capital base by attracting and training a new generation of talent.” The major objectives listed in the HCD goal include education and training, outreach to universities and professional societies, postdoctoral appointments, and summer internships at national laboratories.

  2. Stages of change for physical activity and dietary habits in persons with type 2 diabetes included in a mobile health intervention: the Norwegian study in RENEWING HEALTH.

    Science.gov (United States)

    Holmen, Heidi; Wahl, Astrid; Torbjørnsen, Astrid; Jenum, Anne Karen; Småstuen, Milada Cvancarova; Ribu, Lis

    2016-01-01

    The aim of this study was to investigate stages of change for physical activity and dietary habits using baseline data from persons with type 2 diabetes included in a mobile health intervention. We examined the associations between stages of change for physical activity change and dietary change, and between stages of change for each behavior and individual characteristics, health-related quality of life, self-management, depressive symptoms, and lifestyle. We examined 151 persons with type 2 diabetes with an glycated hemoglobin (HbA1c) level ≥7.1%, aged ≥18 years at baseline of a randomized controlled trial, before testing a mobile app with or without health counseling. Stages of change were dichotomized into 'pre-action' and 'action'. Self-management was measured using the Health Education Impact Questionnaire (heiQ) where a higher score reflects increased self-management, and health-related quality of life was measured with the Short-Form-36 (SF-36). Logistic regression modeling was performed. The median HbA1c level was 7.9% (7.1-12.4), 90% were overweight or obese, and 20% had ≥3 comorbidities. 58% were in the preaction stage for physical activity change and 79% in the preaction stage for dietary change. Higher scores of self-management were associated with an increased chance of being in the action stage for both dietary change and physical activity change. Higher body mass index was associated with an 8% reduced chance of being in the action stage for physical activity change (OR 0.92, 95% CI 0.86 to 0.99). Being in the action stage was associated with higher scores of self-management, crucial for type 2 diabetes. Over half of the participants were in the preaction stage for physical activity and dietary change, and many had a high disease burden with comorbidities and overweight. NCT01315756.

  3. Validity and reliability of an adapted arabic version of the long international physical activity questionnaire.

    Science.gov (United States)

    Helou, Khalil; El Helou, Nour; Mahfouz, Maya; Mahfouz, Yara; Salameh, Pascale; Harmouche-Karaki, Mireille

    2017-07-24

    The International Physical Actvity Questionnaire (IPAQ) is a validated tool for physical activity assessment used in many countries however no Arabic version of the long-form of this questionnaire exists to this date. Hence, the aim of this study was to cross-culturally adapt and validate an Arabic version of the long International Physical Activity Questionnaire (AIPAQ) equivalent to the French version (F-IPAQ) in a Lebanese population. The guidelines for cross-cultural adaptation provided by the World Health Organization and the International Physical Activity Questionnaire committee were followed. One hundred fifty-nine students and staff members from Saint Joseph University of Beirut were randomly recruited to participate in the study. Items of the A-IPAQ were compared to those from the F-IPAQ for concurrent validity using Spearman's correlation coefficient. Content validity of the questionnaire was assessed using factor analysis for the A-IPAQ's items. The physical activity indicators derived from the A-IPAQ were compared with the body mass index (BMI) of the participants for construct validity. The instrument was also evaluated for internal consistency reliability using Cronbach's alpha and Intraclass Correlation Coefficient (ICC). Finally, thirty-one participants were asked to complete the A-IPAQ on two occasions three weeks apart to examine its test-retest reliability. Bland-Altman analyses were performed to evaluate the extent of agreement between the two versions of the questionnaire and its repeated administrations. A high correlation was observed between answers of the F-IPAQ and those of the A-IPAQ, with Spearman's correlation coefficients ranging from 0.91 to 1.00 (p reliability with Cronbach's alpha ranging from 0.769-1.00 (p reliability for most of its items (ICC ranging from 0.66-0.96; p validity and reliability for the assessment of physical activity among Lebanese adults. More studies are necessary in the future to assess its validity compared

  4. IPSN international activities in 1999; Les activites internationales de l'IPSN en 1999

    Energy Technology Data Exchange (ETDEWEB)

    Anon

    2000-09-01

    This article is a reprint of a chapter taken from the 1999 activity report of the French Institute of Nuclear Protection and Safety (IPSN) and devoted to the international activities of the IPSN, in particular the cooperation of IPSN with its German homologue GRS (Gesellschaft fuer Anlagen und Reaktorsicherheit): assistance to Eastern Europe countries (development of regulation and constitution of safety files in Ukraine, transfer of computer codes and training, safety evaluation of the Mochvce nuclear power plant in Slovakia, reduction of the risks generated by the Tchernobyl shelter, assistance for the decommissioning of the Tchernobyl power plant, analysis of improvements proposed for the Medzamor unit 2 of Armenia, evaluation of fire hazard risks, assistance to Lithuania for the licensing of the Ignalina 1 unit); cooperation with China; international cooperation about the methods and tools for crisis management; international collaboration about IPSN's serious accident codes; extension of cooperation with Japan in radiation protection and radio-ecology; nuclear safety exercises in Russia and Armenia; development of Russia's national control of nuclear materials; collaboration with the medical radiological research center of Obninsk (Russia); radiation protection assistance in Turkey after a source accident; neutron measurements at the Vandellos 2 power plant (Spain); European intercomparison of neutron dosimetry; international intercomparison of uranium dosimetry in urines; participation to European research programs; construction of a database about the Tchernobyl accident consequences; organization of the Eurosafe European forum on the safety of nuclear facilities; development and validation of the Astec computer code for the simulation of nuclear accidents; evaluation report concerning the French-German EPR reactor project. (J.S.)

  5. What does an intern doctor actually do? A quantification of time on work activities

    Directory of Open Access Journals (Sweden)

    James Jia Jun Chen

    2017-12-01

    Full Text Available Background Interns, or first year junior doctors, have traditionally been used as an adaptable frontline solution to many of the changes in healthcare, utilising their broad skill sets for both direct patient care and administrative burdens. While there are studies that focus on the total hours junior doctors work, there are few that analyse the specific tasks they do and how they dedicate their work time. Aims We aim to quantify the amount of time intern doctors spent on specific tasks during a shift. Methods This is a multi-centred, retrospective, self-reported study that was carried out in a public tertiary hospital network in Western Australia, comprising one tertiary, two metropolitan, and three regional hospitals. 68 individual shifts were reported, accounting for 605.72 hours. Participants reported time spent, in fifteen minute segments, on categories grossly defined as clerical tasks, clinical tasks, teaching, and personal time. Participants were also asked about their satisfaction with the amount of clinical exposure during the reported shift. Results Direct patient care accounted for 22 per cent of total shift time, indirect care 74 per cent, and personal time 4 per cent. Discharge summaries accounted for the most time-per-shift at 26 per cent, followed by medical note documentation at 14 per cent, with the least being teaching at 2 per cent. Direct patient contact by interns during a shift was on average 12 per cent (SD 14 per cent. 12 interns or 18 per cent of all responses reported no direct patient contact (0 per cent during a shift. Interns working in emergency medicine spent 44 per cent of their shift on direct patient contact, significantly more compared to their medicine and surgical colleagues. Conclusion Indirect care activities consume almost three times as much time as direct care activities. Interns are mostly unsatisfied with their amount of clinical exposure per shift. The results concur with the current literature of

  6. Use of an activated beta-catenin to identify Wnt pathway target genes in caenorhabditis elegans, including a subset of collagen genes expressed in late larval development.

    Science.gov (United States)

    Jackson, Belinda M; Abete-Luzi, Patricia; Krause, Michael W; Eisenmann, David M

    2014-04-16

    The Wnt signaling pathway plays a fundamental role during metazoan development, where it regulates diverse processes, including cell fate specification, cell migration, and stem cell renewal. Activation of the beta-catenin-dependent/canonical Wnt pathway up-regulates expression of Wnt target genes to mediate a cellular response. In the nematode Caenorhabditis elegans, a canonical Wnt signaling pathway regulates several processes during larval development; however, few target genes of this pathway have been identified. To address this deficit, we used a novel approach of conditionally activated Wnt signaling during a defined stage of larval life by overexpressing an activated beta-catenin protein, then used microarray analysis to identify genes showing altered expression compared with control animals. We identified 166 differentially expressed genes, of which 104 were up-regulated. A subset of the up-regulated genes was shown to have altered expression in mutants with decreased or increased Wnt signaling; we consider these genes to be bona fide C. elegans Wnt pathway targets. Among these was a group of six genes, including the cuticular collagen genes, bli-1 col-38, col-49, and col-71. These genes show a peak of expression in the mid L4 stage during normal development, suggesting a role in adult cuticle formation. Consistent with this finding, reduction of function for several of the genes causes phenotypes suggestive of defects in cuticle function or integrity. Therefore, this work has identified a large number of putative Wnt pathway target genes during larval life, including a small subset of Wnt-regulated collagen genes that may function in synthesis of the adult cuticle.

  7. International Project on Innovative Nuclear Reactors and Fuel Cycles: Introduction and Education and Training Activity

    International Nuclear Information System (INIS)

    Fesenko, G.; Kuznetsov, V.; Phillips, J.R.; Rho, K.; Grigoriev, A.; Korinny, A.; Ponomarev, A.

    2015-01-01

    The IAEA’s International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO) was established in 2000 through IAEA General Conference resolution with aim to ensure that sustainable nuclear energy is available to help meet the energy needs of the 21st century. INPRO seeks to bring together technology holders, users and newcomers to consider jointly the international and national actions required for achieving desired innovations in nuclear reactors and fuel cycles, with a particular focus on sustainability and needs of developing countries. It is a mechanism for INPRO Members to collaborate on topics of joint interest. INPRO activities are undertaken in close cooperation with Member States in the following main areas: Global Scenarios, Innovations, Sustainability Assessment and Strategies, Policy and Dialogue. The paper presents short introduction in INPRO and specifically the distant Education and Training INPRO activity on important topics of nuclear energy sustainability to audiences in different Member States. These activities can support capacity building and national human resource development in the nuclear energy sector. The main benefit of such training courses and workshops is that it is not only targeted to students, but also to lecturers of technical and nuclear universities. Moreover, young professionals working at nuclear energy departments, electric utilities, energy ministries and R&D institutions can participate in such training and benefit from it. (authors)

  8. Trends in CO2 Emissions from China-Oriented International Marine Transportation Activities and Policy Implications

    Directory of Open Access Journals (Sweden)

    Hualong Yang

    2017-07-01

    Full Text Available The demand for marine transportation and its associated CO2 emissions are growing rapidly as a result of increasing international trade and economic growth. An activity-based approach is developed for forecasting CO2 emissions from the China-oriented international seaborne trade sector. To accurately estimate the aggregated emissions, CO2 emissions are calculated individually for five categories of vessels: crude oil tanker, product tanker, chemical tanker, bulk carrier, and container. A business-as-usual (BAU scenario was developed to describe the current situation without additional mitigation policies, whilst three alternative scenarios were developed to describe scenarios with various accelerated improvements of the key factors. The aggregated CO2 emissions are predicted to reach 419.97 Mt under the BAU scenario, and 258.47 Mt under the optimal case, AD3. These predictions are 4.5 times and 2.8 times that of the aggregated emissions in 2007. Our analysis suggests that regulations for monitoring, reporting, and verifying the activities of vessels should be proposed, in order to quantify the CO2 emissions of marine transportation activities in Chinese territorial waters. In the long-term future, mitigation policies should be employed to reduce CO2 emissions from the marine trade sector and to address the climatic impact of shipping.

  9. Relationship between smartphone addiction and physical activity in Chinese international students in Korea.

    Science.gov (United States)

    Kim, Sung-Eun; Kim, Jin-Woo; Jee, Yong-Seok

    2015-09-01

    Excessive usage of smartphones may induce social problems, such as depression and impairment of social and emotional functioning. Moreover, its usage can impede physical activity, but the relationship between smartphone addiction and physical activity is obscure. Therefore, we examined the relationship and the impact of excessive smartphone use on physical activity. This study collected data through the structured questionnaire consisting of general characteristics, the number and hours of smartphone usage, and the Smartphone Addiction Proneness Scale (SAPS) from 110 Chinese international students in Korea. The body composition and physical activity, such as the total daily number of steps and consumed calories, were measured. In this study, high-risk smartphone users showed less physical activity, such as the total number of steps taken and the average consumed calories per day. Moreover, their body composition, such as muscle mass and fat mass, was significantly different. Among these factors, the hours of smartphone use revealed the proportional relationship with smartphone addiction (β = 0.209, p = 0.026), while the average number of walking steps per day showed a significant reverse proportional tendency in participants with smartphone addiction (β = -0.883, p smartphone addiction were less likely to walk for each day. Namely, smartphone addiction may negatively influence physical health by reducing the amount of physical activity, such as walking, resulting in an increase of fat mass and a decrease of muscle mass associated with adverse health consequences.

  10. Integrating science and education during an international, multi-parametric investigation of volcanic activity at Santiaguito volcano, Guatemala

    Science.gov (United States)

    Lavallée, Yan; Johnson, Jeffrey; Andrews, Benjamin; Wolf, Rudiger; Rose, William; Chigna, Gustavo; Pineda, Armand

    2016-04-01

    In January 2016, we held the first scientific/educational Workshops on Volcanoes (WoV). The workshop took place at Santiaguito volcano - the most active volcano in Guatemala. 69 international scientists of all ages participated in this intensive, multi-parametric investigation of the volcanic activity, which included the deployment of seismometers, tiltmeters, infrasound microphones and mini-DOAS as well as optical, thermographic, UV and FTIR cameras around the active vent. These instruments recorded volcanic activity in concert over a period of 3 to 9 days. Here we review the research activities and present some of the spectacular observations made through this interdisciplinary efforts. Observations range from high-resolution drone and IR footage of explosions, monitoring of rock falls and quantification of the erupted mass of different gases and ash, as well as morphological changes in the dome caused by recurring explosions (amongst many other volcanic processes). We will discuss the success of such integrative ventures in furthering science frontiers and developing the next generation of geoscientists.

  11. US enrichment safeguards program development activities with potential International Atomic Energy Agency safeguards applications. Part 1. Executive summaries

    International Nuclear Information System (INIS)

    Swindle, D.W. Jr.

    1984-07-01

    The most recent progress, results, and plans for future work on the US Enrichment Safeguards Program's principal development activities are summarized. Nineteen development activities are reported that have potential International Atomic Energy Agency (IAEA) safeguards applications. Part 1 presents Executive Summaries for these, each of which includes information on (1) the purpose and scope of the development activity; (2) the potential IAEA safeguards application and/or use if adopted; (3) significant development work, results, and/or conclusions to date; and where appropriate (4) future activities and plans for continued work. Development activities cover: measurement technology for limited-frequency-unannounced-access stategy inspections; integrated data acquisition system; enrichment-monitoring system; load-cell-based weighing system for UF 6 cylinder mass verifications; vapor phase versus liquid phase sampling of UF 6 cylinders; tamper-safing hardware and systems; an alternative approach to IAEA nuclear material balance verifications resulting from intermittent inspections; UF 6 sample bottle enrichment analyzer; crated waste assay monitor; and compact 252 Cf shuffler for UF 6 measurements

  12. Wakame and Nori in restructured meats included in cholesterol-enriched diets affect the antioxidant enzyme gene expressions and activities in Wistar rats.

    Science.gov (United States)

    Moreira, Adriana Schultz; González-Torres, Laura; Olivero-David, Raul; Bastida, Sara; Benedi, Juana; Sánchez-Muniz, Francisco J

    2010-09-01

    The effects of diets including restructured meats (RM) containing Wakame or Nori on total liver glutathione status, and several antioxidant enzyme gene expressions and activities were tested. Six groups of ten male growing Wistar rats each were fed a mix of 85% AIN-93 M diet and 15% freeze-dried RM for 35 days. The control group (C) consumed control RM, the Wakame (W) and the Nori (N) groups, RM with 5% Wakame and 5% Nori, respectively. Animals on added cholesterol diets (CC, CW, and CN) consumed their corresponding basal diets added with cholesterol (2%) and cholic acid (0.4%). Alga and dietary cholesterol significantly interact (P Nori-RM is a hypocholesterolemic food while Wakame-RM is an antioxidant food. This should be taken into account when including this kind of RM as potential functional foods in human.

  13. Review of international geothermal activities and assessment of US industry opportunities: Summary report

    Energy Technology Data Exchange (ETDEWEB)

    1987-08-01

    This report summarizes a study initiated to review and assess international developments in the geothermal energy field and to define business opportunities for the US geothermal industry. The report establishes data bases on the status of worldwide geothermal development and the competitiveness of US industry. Other factors identified include existing legislation, tax incentives, and government institutions or agencies and private sector organizations that promote geothermal exports. Based on the initial search of 177 countries and geographic entities, 71 countries and areas were selected as the most likely targets for the expansion of the geothermal industry internationally. The study then determined to what extent their geothermal resource had been developed, what countries had aided or participated in this development, and what plans existed for future development. Data on the energy, economic, and financial situations were gathered.

  14. Review of international geothermal activities and assessment of US industry opportunities: Final report

    Energy Technology Data Exchange (ETDEWEB)

    1987-08-01

    This study was initiated to review and assess international developments in the geothermal energy field and to define business opportunities for the US geothermal industry. The report establishes data bases on the status of worldwide geothermal development and the competitiveness of US industry. Other factors identified include existing legislation, tax incentives, and government institutions or agencies and private sector organizations that promote geothermal exports. Based on the initial search of 177 countries and geographic entities, 71 countries and areas were selected as the most likely targets for the expansion of the geothermal industry internationally. The study then determined to what extent their geothermal resource had been developed, what countries had aided or participated in this development, and what plans existed for future development. Data on the energy, economic, and financial situations were gathered.

  15. [Relating costs to activities in hospitals. Use of internal cost accounting].

    Science.gov (United States)

    Stavem, K

    1995-01-10

    During the last few years hospital cost accounting has become widespread in many countries, in parallel with increasing cost pressure, greater competition and new financing schemes. Cost accounting has been used in the manufacturing industry for many years. Costs can be related to activities and production, e.g. by the costing of procedures, episodes of care and other internally defined cost objectives. Norwegian hospitals have lagged behind in the adoption of cost accounting. They ought to act quickly if they want to be prepared for possible changes in health care financing. The benefits can be considerable to a hospital operating in a rapidly changing health care environment.

  16. Rare earths analysis of rock samples by instrumental neutron activation analysis, internal standard method

    International Nuclear Information System (INIS)

    Silachyov, I.

    2016-01-01

    The application of instrumental neutron activation analysis for the determination of long-lived rare earth elements (REE) in rock samples is considered in this work. Two different methods are statistically compared: the well established external standard method carried out using standard reference materials, and the internal standard method (ISM), using Fe, determined through X-ray fluorescence analysis, as an element-comparator. The ISM proved to be the more precise method for a wide range of REE contents and can be recommended for routine practice. (author)

  17. Active control of internal transport barrier and confinement database in JT-60U reversed shear plasma

    Energy Technology Data Exchange (ETDEWEB)

    Sakamoto, Yoshiteru; Takizuka, Tomonori; Shirai, Hiroshi; Fujita, Takaaki; Kamada, Yutaka; Ide, Shunsuke; Fukuda, Takeshi; Koide, Yoshihiko [Japan Atomic Energy Research Inst., Naka, Ibaraki (Japan). Naka Fusion Research Establishment

    2001-07-01

    Active control of internal transport barrier (ITB) and confinement properties of plasma with ITB have been studied in reversed shear plasmas. Modifications of the radial electric field (E{sub r}) profile by changing the combination of tangential neutral beams can control the ITB strength, where the contribution to E{sub r} from the toroidal rotation plays an important role. The ITB confinement database of reversed shear plasmas has been constructed. Stored energy is strongly correlated with poloidal magnetic field at the ITB foot. (author)

  18. How the national prices impact the international activity? The case of oilive oil market in Spain

    OpenAIRE

    Aubert, Magali; Demaria, Federica; Gutiérrez-Salcedo, Maria

    2014-01-01

    Olive oil plays an important role in the European Union countries where Spain, Italy and Greece are the main actors. Spain industry knew a flourished period by confirming its own leadership in this sector. Spain is the main olive oil producer and exporter in the world. Starting from this evidence, the main objective of this work is that of analysing the price transmission at the national level to understand in which way this activity has some impact on the international ones. At first we look...

  19. Reliability of the Serbian version of the International Physical Activity Questionnaire for older adults

    Directory of Open Access Journals (Sweden)

    Milanović Z

    2014-04-01

    Full Text Available Zoran Milanović,1 Saša Pantelić,1 Nebojša Trajković,1 Bojan Jorgić,1 Goran Sporiš,2 Milovan Bratić1 1Faculty of Sport and Physical Education, University of Niš, Niš, Serbia; 2Faculty of Kinesiology, University of Zagreb, Zagreb, Croatia Abstract: The purpose of this study was to determine the test–retest reliability of the International Physical Activity Questionnaire (IPAQ for older adults in Serbia. Six hundred and sixty older adults (352 men, 53%; 308 women, 47%; mean age 67.65±5.76 years participated in the study. To examine test–retest reliability, the participants were asked to complete the IPAQ on two occasions 2 weeks apart. Moderate reliability was observed between the repeated IPAQ, with intraclass correlation coefficients ranging from 0.53 to 0.91. The least reliability was established in leisure time activity (0.53 and the most reliability in the transport domain (0.91. Men and women had similar intraclass correlation coefficients for total physical activity (0.71 versus 0.74, respectively, while the biggest difference was obtained for housework in men (0.68 and in women (0.90. Our study shows that the long version of the IPAQ is a reliable instrument for assessing physical activity levels in older adults and that it may be useful for generating internationally comparable data. Keywords: questionnaire, elderly, IPAQ, physical activity

  20. Post-Polio Health International including International Ventilator Users Network

    Science.gov (United States)

    ... PHI Annual Reports Contact Us Copyright EDUCATION Post-Polio Health newsletter Health Care Considerations Handbook on the Late Effects ... Late Effects of Polio Post-Polio Syndrome (PPS) About Acute Polio Major ...

  1. Motivations for adolescent participation in leisure-time physical activity: international differences.

    Science.gov (United States)

    Iannotti, Ronald J; Chen, Rusan; Kololo, Hania; Petronyte, Gintare; Haug, Ellen; Roberts, Chris

    2013-01-01

    Although there are substantial international differences in adolescent physical activity (PA), cross-country motivational differences have received limited attention, perhaps due to the lack of measures applicable internationally. Identical self-report measures assessing PA and motivations for PA were used to survey students ages 11, 13, and 15 from 7 countries participating in the 2005-2006 Health Behavior in School-Aged Children (HBSC) study representing 3 regions: Eastern Europe, Western Europe and North America. Multigroup comparisons with Confirmatory Factor Analysis and Structural Equation Modeling examined the stability of factors across regions and regional differences in relations between PA and motives for PA. Three PA motivation factors were identified as suitable for assessing international populations. There were significant regional, gender, and age differences in relations between PA and each of the 3 PA motives. Social and achievement motives were positively related to PA. However, the association of PA with health motivations varied significantly by region and gender. The patterns suggest the importance of social motives for PA and the possibility that health may not be a reliable motivator for adolescent PA. Programs to increase PA in adolescence need to determine which motives are effective for the particular population being targeted.

  2. Lightning Imaging Sensor (LIS) on the International Space Station (ISS): Launch, Installation, Activation, and First Results

    Science.gov (United States)

    Blakeslee, R. J.; Christian, H. J., Jr.; Mach, D. M.; Buechler, D. E.; Koshak, W. J.; Walker, T. D.; Bateman, M. G.; Stewart, M. F.; O'Brien, S.; Wilson, T. O.; Pavelitz, S. D.; Coker, C.

    2016-12-01

    Over the past 20 years, the NASA Marshall Space Flight Center, the University of Alabama in Huntsville, and their partners developed and demonstrated the effectiveness and value of space-based lightning observations as a remote sensing tool for Earth science research and applications, and, in the process, established a robust global lightning climatology. The observations included measurements from the Lightning Imaging Sensor (LIS) on the Tropical Rainfall Measuring Mission (TRMM) and its Optical Transient Detector (OTD) predecessor that acquired global observations of total lightning (i.e., intracloud and cloud-to-ground discharges) spanning a period from May 1995 through April 2015. As an exciting follow-on to these prior missions, a space-qualified LIS built as a flight-spare for TRMM will be delivered to the International Space Station (ISS) for a 2 year or longer mission, flown as a hosted payload on the Department of Defense (DoD) Space Test Program-Houston 5 (STP-H5) mission. The STP-H5 payload containing LIS is scheduled launch from NASA's Kennedy Space Center to the ISS in November 2016, aboard the SpaceX Cargo Resupply Services-10 (SpaceX-10) mission, installed in the unpressurized "trunk" of the Dragon spacecraft. After the Dragon is berth to ISS Node 2, the payload will be removed from the trunk and robotically installed in a nadir-viewing location on the external truss of the ISS. Following installation on the ISS, the LIS Operations Team will work with the STP-H5 and ISS Operations Teams to power-on LIS and begin instrument checkout and commissioning. Following successful activation, LIS orbital operations will commence, managed from the newly established LIS Payload Operations Control Center (POCC) located at the National Space Science Technology Center (NSSTC) in Huntsville, AL. The well-established and robust processing, archival, and distribution infrastructure used for TRMM was easily adapted to the ISS mission, assuring that lightning

  3. Waste management assessment and technical review programme. WATRP. An international peer review service for radioactive waste management activities

    International Nuclear Information System (INIS)

    1994-09-01

    International Atomic Energy Agency provides international peer review services in radioactive waste management to those Member States that have established radioactive waste management programmes. Such services are provided within Waste Management Assessment and Technical Review Programme (WATRP). The main objective of WATRP is to provide international expertise and information on a requested subject in the field of radioactive waste management and to validate that programmes and activities are sound and performing well. Refs, figs and tabs

  4. Activator Gcn4 employs multiple segments of Med15/Gal11, including the KIX domain, to recruit mediator to target genes in vivo.

    Science.gov (United States)

    Jedidi, Iness; Zhang, Fan; Qiu, Hongfang; Stahl, Stephen J; Palmer, Ira; Kaufman, Joshua D; Nadaud, Philippe S; Mukherjee, Sujoy; Wingfield, Paul T; Jaroniec, Christopher P; Hinnebusch, Alan G

    2010-01-22

    Mediator is a multisubunit coactivator required for initiation by RNA polymerase II. The Mediator tail subdomain, containing Med15/Gal11, is a target of the activator Gcn4 in vivo, critical for recruitment of native Mediator or the Mediator tail subdomain present in sin4Delta cells. Although several Gal11 segments were previously shown to bind Gcn4 in vitro, the importance of these interactions for recruitment of Mediator and transcriptional activation by Gcn4 in cells was unknown. We show that interaction of Gcn4 with the Mediator tail in vitro and recruitment of this subcomplex and intact Mediator to the ARG1 promoter in vivo involve additive contributions from three different segments in the N terminus of Gal11. These include the KIX domain, which is a critical target of other activators, and a region that shares a conserved motif (B-box) with mammalian coactivator SRC-1, and we establish that B-box is a critical determinant of Mediator recruitment by Gcn4. We further demonstrate that Gcn4 binds to the Gal11 KIX domain directly and, by NMR chemical shift analysis combined with mutational studies, we identify the likely binding site for Gcn4 on the KIX surface. Gcn4 is distinctive in relying on comparable contributions from multiple segments of Gal11 for efficient recruitment of Mediator in vivo.

  5. Kinetic and Mechanistic Study of the pH-Dependent Activation (Epoxidation) of Prodrug Treosulfan Including the Reaction Inhibition in a Borate Buffer.

    Science.gov (United States)

    Romański, Michał; Ratajczak, Whitney; Główka, Franciszek

    2017-07-01

    A prodrug treosulfan (T) undergoes a pH-dependent activation to epoxide derivatives. The process seems to involve an intramolecular Williamson reaction (IWR) but clear kinetic evidence is lacking. Moreover, a cis-diol system present in the T structure is expected to promote complexation with boric acid. As a result, the prodrug epoxidation would be inhibited; however, this phenomenon has not been investigated. In this article, the effect of pH on the kinetics of T conversion to its monoepoxide was studied from a mechanistic point of view. Also, the influence of boric acid on the reaction kinetics was examined. The rate constants observed for the activation of T (k obs ) in acetate, phosphate, and carbonate buffers satisfied the equation logk obs  = -7.48 + 0.96 pH. The reaction was inhibited in the excess of boric acid over T, and the k obs decreased with increasing borate buffer concentration. The experimental results were consistent with the inhibition model that included the formation of a tetrahedral, anionic T-boric acid monoester. To conclude, in nonborate buffers, the T activation to (2S,3S)-1,2-epoxybutane-3,4-diol 4-methanesulfonate follows IWR mechanism. A borate buffer changes the reaction kinetics and complicates kinetic analysis. Copyright © 2017 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.

  6. Life stories of people with rheumatoid arthritis who retired early: how gender and other contextual factors shaped their everyday activities, including paid work.

    Science.gov (United States)

    Stamm, T A; Machold, K P; Smolen, J; Prodinger, B

    2010-06-01

    The aim of the present study was to explore how contextual factors affect the everyday activities of women and men with rheumatoid arthritis (RA), as evident in their life stories. Fifteen people with RA, who had retired early due to the disease, were interviewed up to three times, according to a narrative biographic interview style. The life stories of the participants, which were reconstructed from the biographical data and from the transcribed 'told story' were analysed from the perspective of contextual factors, including personal and environmental factors. The rigour and accuracy of the analysis were enhanced by reflexivity and peer-review of the results. The life stories of the participants in this study reflected how contextual factors (such as gender, the healthcare system, the support of families and social and cultural values) shaped their everyday activities. In a society such as in Austria, which is based on traditional patriarchal values, men were presented with difficulties in developing a non-paid-work-related role. For women, if paid work had to be given up, they were more likely to engage in alternative challenging activities which enabled them to develop reflective skills, which in turn contributed to a positive and enriching perspective on their life stories. Health professionals may thus use some of the women's strategies to help men. Interventions by health professionals in people with RA may benefit from an approach sensitive to personal and environmental factors.

  7. Why combine diet and physical activity in the same international research society?

    Directory of Open Access Journals (Sweden)

    Baranowski Tom

    2004-02-01

    Full Text Available Abstract Research in diet and physical activity in the U.S. started in very different traditions, with behavioral science input being uneven in their development. Investigators and policy makers in Europe have recognized the complementarity of diet and physical activity and incorporated them both under the label Public Health Nutrition. Joining these disciplines internationally offers the opportunity to benefit all, since the problems addressed are human, not specific to any one country. In regard to why combine diet and physical activity, at the biological level, there is reason to believe that diet and physical activity working in concert can remodel physiological structures and processes toward healthful ends. The diet and physical activity behaviors themselves vary in characteristics and are similar in others. The behavioral science components of these two disciplines face similar problems, and can learn from the advances made by the other, in the areas of measurement, correlates and intervention. By working together, knowledge will be enhanced from uncovering complementary and interactive relationships between diet and physical activity, and in relation to disease risks, that may result in designing more effective and efficient interventions and policies. Since the behavioral sciences are at a disadvantage in comparison to the biological sciences in terms of scientific advances and thereby capturing the popular imagination for solutions to health problems, we must redouble our efforts to enhance funding for behavioral research in regard to diet and physical activity and to make the research advances necessary to prevent the medicalizing of essentially social and behavioral problems. Nutrition and physical activity should most effectively do this together.

  8. Regulated internalization of NMDA receptors drives PKD1-mediated suppression of the activity of residual cell-surface NMDA receptors.

    Science.gov (United States)

    Fang, Xiao-Qian; Qiao, Haifa; Groveman, Bradley R; Feng, Shuang; Pflueger, Melissa; Xin, Wen-Kuan; Ali, Mohammad K; Lin, Shuang-Xiu; Xu, Jindong; Duclot, Florian; Kabbaj, Mohamed; Wang, Wei; Ding, Xin-Sheng; Santiago-Sim, Teresa; Jiang, Xing-Hong; Salter, Michael W; Yu, Xian-Min

    2015-11-19

    Constitutive and regulated internalization of cell surface proteins has been extensively investigated. The regulated internalization has been characterized as a principal mechanism for removing cell-surface receptors from the plasma membrane, and signaling to downstream targets of receptors. However, so far it is still not known whether the functional properties of remaining (non-internalized) receptor/channels may be regulated by internalization of the same class of receptor/channels. The N-methyl-D-aspartate receptor (NMDAR) is a principal subtype of glutamate-gated ion channel and plays key roles in neuronal plasticity and memory functions. NMDARs are well-known to undergo two types of regulated internalization - homologous and heterologous, which can be induced by high NMDA/glycine and DHPG, respectively. In the present work, we investigated effects of regulated NMDAR internalization on the activity of residual cell-surface NMDARs and neuronal functions. In electrophysiological experiments we discovered that the regulated internalization of NMDARs not only reduced the number of cell surface NMDARs but also caused an inhibition of the activity of remaining (non-internalized) surface NMDARs. In biochemical experiments we identified that this functional inhibition of remaining surface NMDARs was mediated by increased serine phosphorylation of surface NMDARs, resulting from the activation of protein kinase D1 (PKD1). Knockdown of PKD1 did not affect NMDAR internalization but prevented the phosphorylation and inhibition of remaining surface NMDARs and NMDAR-mediated synaptic functions. These data demonstrate a novel concept that regulated internalization of cell surface NMDARs not only reduces the number of NMDARs on the cell surface but also causes an inhibition of the activity of remaining surface NMDARs through intracellular signaling pathway(s). Furthermore, modulating the activity of remaining surface receptors may be an effective approach for treating receptor

  9. Antibacterial and antibiotic resistance modifying activity of the extracts from Allanblackia gabonensis, Combretum molle and Gladiolus quartinianus against Gram-negative bacteria including multi-drug resistant phenotypes.

    Science.gov (United States)

    Fankam, Aimé G; Kuiate, Jules R; Kuete, Victor

    2015-06-30

    Bacterial resistance to antibiotics is becoming a serious problem worldwide. The discovery of new and effective antimicrobials and/or resistance modulators is necessary to tackle the spread of resistance or to reverse the multi-drug resistance. We investigated the antibacterial and antibiotic-resistance modifying activities of the methanol extracts from Allanblackia gabonensis, Gladiolus quartinianus and Combretum molle against 29 Gram-negative bacteria including multi-drug resistant (MDR) phenotypes. The broth microdilution method was used to determine the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations (MBC) of the samples meanwhile the standard phytochemical methods were used for the preliminary phytochemical screening of the plant extracts. Phytochemical analysis showed the presence of alkaloids, flavonoids, phenols and tannins in all studied extracts. Other chemical classes of secondary metabolites were selectively presents. Extracts from A. gabonensis and C. molle displayed a broad spectrum of activity with MICs varying from 16 to 1024 μg/mL against about 72.41% of the tested bacteria. The extract from the fruits of A. gabonensis had the best activity, with MIC values below 100 μg/mL on 37.9% of tested bacteria. Percentages of antibiotic-modulating effects ranging from 67 to 100% were observed against tested MDR bacteria when combining the leaves extract from C. molle (at MIC/2 and MIC/4) with chloramphenicol, kanamycin, streptomycin and tetracycline. The overall results of the present study provide information for the possible use of the studied plant, especially Allanblackia gabonensis and Combretum molle in the control of Gram-negative bacterial infections including MDR species as antibacterials as well as resistance modulators.

  10. Disposal R&D in the Used Fuel Disposition Campaign: A Discussion of Opportunities for Active International Collaboration

    Energy Technology Data Exchange (ETDEWEB)

    Birkholzer, J.T.

    2011-06-01

    For DOE's Used Fuel Disposition Campaign (UFDC), international collaboration is a beneficial and cost-effective strategy for advancing disposal science with regards to multiple disposal options and different geologic environments. While the United States disposal program focused solely on Yucca Mountain tuff as host rock over the past decades, several international programs have made significant progress in the characterization and performance evaluation of other geologic repository options, most of which are very different from the Yucca Mountain site in design and host rock characteristics. Because Yucca Mountain was so unique (e.g., no backfill, unsaturated densely fractured tuff), areas of direct collaboration with international disposal programs were quite limited during that time. The decision by the U.S. Department of Energy to no longer pursue the disposal of high-level radioactive waste and spent fuel at Yucca Mountain has shifted UFDC's interest to disposal options and geologic environments similar to those being investigated by disposal programs in other nations. Much can be gained by close collaboration with these programs, including access to valuable experience and data collected over recent decades. Such collaboration can help to efficiently achieve UFDC's long-term goals of conducting 'experiments to fill data needs and confirm advanced modeling approaches' (by 2015) and of having a 'robust modeling and experimental basis for evaluation of multiple disposal system options' (by 2020). This report discusses selected opportunities of active international collaboration, with focus on both Natural Barrier System (NBS) and Engineered Barrier System (EBS) aspects and those opportunities that provide access to field data (and respective interpretation/modeling) or allow participation in ongoing field experiments. This discussion serves as a basis for the DOE/NE-53 and UFDC planning process for FY12 and beyond.

  11. Disposal R and D in the Used Fuel Disposition Campaign: A Discussion of Opportunities for Active International Collaboration

    International Nuclear Information System (INIS)

    Birkholzer, J.T.

    2011-01-01

    For DOE's Used Fuel Disposition Campaign (UFDC), international collaboration is a beneficial and cost-effective strategy for advancing disposal science with regards to multiple disposal options and different geologic environments. While the United States disposal program focused solely on Yucca Mountain tuff as host rock over the past decades, several international programs have made significant progress in the characterization and performance evaluation of other geologic repository options, most of which are very different from the Yucca Mountain site in design and host rock characteristics. Because Yucca Mountain was so unique (e.g., no backfill, unsaturated densely fractured tuff), areas of direct collaboration with international disposal programs were quite limited during that time. The decision by the U.S. Department of Energy to no longer pursue the disposal of high-level radioactive waste and spent fuel at Yucca Mountain has shifted UFDC's interest to disposal options and geologic environments similar to those being investigated by disposal programs in other nations. Much can be gained by close collaboration with these programs, including access to valuable experience and data collected over recent decades. Such collaboration can help to efficiently achieve UFDC's long-term goals of conducting 'experiments to fill data needs and confirm advanced modeling approaches' (by 2015) and of having a 'robust modeling and experimental basis for evaluation of multiple disposal system options' (by 2020). This report discusses selected opportunities of active international collaboration, with focus on both Natural Barrier System (NBS) and Engineered Barrier System (EBS) aspects and those opportunities that provide access to field data (and respective interpretation/modeling) or allow participation in ongoing field experiments. This discussion serves as a basis for the DOE/NE-53 and UFDC planning process for FY12 and beyond.

  12. Legitimating New Forms of Organizing and New International Activities in the Eyes of Multiple Stakeholders

    DEFF Research Database (Denmark)

    Turcan, Romeo V.

    The research on new venture legitimation strategies is emerging; although, it is yet to form a central line of enquiry in entrepreneurship research. To contribute to this development, this paper explores the process of legitimation in a non-for-profit venture (hereafter as NGO, non-governmental...... organization). The paper explores (1) how this NGO acquired cognitive legitimacy, defined as knowledge about the new form of organizing and new activity and what is needed to succeed in respective sector, and socio-political legitimacy, defined as the value placed on the new form of organizing and new activity...... by its multiple stakeholders; and (2) what legitimation strategies it developed and adopted to legitimate itself in the eyes of its multiple stakeholders. Theoretically, the paper is grounded within legitimation theory. The empirical context is defined by a new, international NGO entering an established...

  13. Proceedings of the second international conference on environmental impact assessment of all economical activities. Vol. 2

    International Nuclear Information System (INIS)

    1993-01-01

    Proceedings of the conference consist of 3 volumes: Vol. 1 - 'Environmental Impact Assessment of all Economical Activities including Industry'; Vol. 2 - 'Air Pollution Control and Prevention'; Vol. 3 - Waste Management and Environmental Problems in Construction Industry'. Out of 32 papers contained in Vol. 2, 4 were inputted to INIS. They deal with nuclear fusion as a potential energy source, with environmental aspects of disposal of ashes from power plants in the Czech Republic, and with land reclamation after mining activities. (Z.S.)

  14. PXR (NR1I2): splice variants in human tissues, including brain, and identification of neurosteroids and nicotine as PXR activators

    International Nuclear Information System (INIS)

    Lamba, Vishal; Yasuda, Kazuto; Lamba, Jatinder K.; Assem, Mahfoud; Davila, Julio; Strom, Stephen; Schuetz, Erin G.

    2004-01-01

    To gain insight on the expression of pregnane X receptor (PXR), we analyzed PXR.1 and PXR alternatively spliced transcripts in a panel of 36 human tissues. PXR.1 was expressed in many more tissues than previously determined, including human bone marrow and select regions of the human brain. In each of these tissues, we observed alternative splicing of various exons of PXR that generated multiple distinct PXR isoforms. The most abundant PXR alternative mRNA transcripts lacked 111 nucleotides, deleting 37 amino acids from the PXR LBD (PXR.2), or lacked 123 nt, deleting 41 amino acids from the PXR LBD (PXR.3). CYP3A4, a gene transcriptionally regulated by PXR, showed incomplete overlap with PXR in its tissue distribution. Quantitation of PXR mRNAs in human liver demonstrated that PXR.2 and PXR.3 represented 6.7% and 0.32% of total PXR mRNA transcripts. Brain expression of PXR prompted analysis of whether some brain acting chemicals were PXR ligands. The neurosteroids allopregnanolone and pregnanolone activated PXR and induced transcription of a CYP3A4-luciferase reporter. Nicotine, the psychoactive and addictive chemical in cigarettes, and a known inducer of brain CYP2B6, was an efficacious activator of PXR and inducer of CYP3A4 transcription. Because nicotine activation of PXR will enhance metabolism of nicotine to the non-psychoactive cotinine, these results provide one molecular mechanism for the development of tolerance to nicotine. Moreover, the identification of PXR in many human tissues, such as brain, and activation by tissue specific ligands (such as neurosteroids) suggests additional biological roles for this receptor in these tissues

  15. PXR (NR1I2): splice variants in human tissues, including brain, and identification of neurosteroids and nicotine as PXR activators.

    Science.gov (United States)

    Lamba, Vishal; Yasuda, Kazuto; Lamba, Jatinder K; Assem, Mahfoud; Davila, Julio; Strom, Stephen; Schuetz, Erin G

    2004-09-15

    To gain insight on the expression of pregnane X receptor (PXR), we analyzed PXR.1 and PXR alternatively spliced transcripts in a panel of 36 human tissues. PXR.1 was expressed in many more tissues than previously determined, including human bone marrow and select regions of the human brain. In each of these tissues, we observed alternative splicing of various exons of PXR that generated multiple distinct PXR isoforms. The most abundant PXR alternative mRNA transcripts lacked 111 nucleotides, deleting 37 amino acids from the PXR LBD (PXR.2), or lacked 123 nt, deleting 41 amino acids from the PXR LBD (PXR.3). CYP3A4, a gene transcriptionally regulated by PXR, showed incomplete overlap with PXR in its tissue distribution. Quantitation of PXR mRNAs in human liver demonstrated that PXR.2 and PXR.3 represented 6.7% and 0.32% of total PXR mRNA transcripts. Brain expression of PXR prompted analysis of whether some brain acting chemicals were PXR ligands. The neurosteroids allopregnanolone and pregnanolone activated PXR and induced transcription of a CYP3A4-luciferase reporter. Nicotine, the psychoactive and addictive chemical in cigarettes, and a known inducer of brain CYP2B6, was an efficacious activator of PXR and inducer of CYP3A4 transcription. Because nicotine activation of PXR will enhance metabolism of nicotine to the non-psychoactive cotinine, these results provide one molecular mechanism for the development of tolerance to nicotine. Moreover, the identification of PXR in many human tissues, such as brain, and activation by tissue specific ligands (such as neurosteroids) suggests additional biological roles for this receptor in these tissues.

  16. IAEA Laboratory Activities. The IAEA Laboratories at Vienna and Seibersdorf, the International Laboratory of Marine Radioactivity at Monaco, the International Centre for Theoretical Physics, Trieste, the Middle Eastern Regional Radioisotope Centre for the Arab Countries, Cairo. Fifth Report

    International Nuclear Information System (INIS)

    1968-01-01

    This fifth report describes development and work during the year 1967. It includes activities of the IAEA Laboratories at Vienna and Seibersdorf, the International Laboratory of Marine Radioactivity at Monaco, the International Centre for Theoretical Physics at Trieste, and the Middle Eastern Regional Radioisotope Centre for the Arab Countries at Cairo. Contents: The IAEA Laboratories at Vienna and Seibersdorf: Introduction; Standardization of measurement and of analytical methods related to peaceful applications of nuclear energy; Services to Member States and International Organizations; Chemical and physico-chemical investigations relevant to the Agency's programme; Nuclear techniques in hydrology; Nuclear techniques in medicine; Nuclear techniques in agriculture; Nuclear electronics service and development; Administrative matters. — The International Laboratory of Marine Radioactivity at Monaco: Introduction; Research; Administrative matters. — The International Centre for Theoretical Physics, Trieste: Assistance to developing countries; Research activities; Administrative matters; Annexes. — The Middle Eastern Regional Radioisotope Centre for the Arab Countries, Cairo: Introduction; The scientific programme of the Centre; Publications on work done at the Centre; Finance; Annex. Entirely in English. (author)

  17. IFMIF - International Fusion Materials Irradiation Facility Conceptual Design Activity/Interim Report

    International Nuclear Information System (INIS)

    Rennich, M.J.

    1995-12-01

    Environmental acceptability, safety, and economic viability win ultimately be the keys to the widespread introduction of fusion power. This will entail the development of radiation- resistant and low- activation materials. These low-activation materials must also survive exposure to damage from neutrons having an energy spectrum peaked near 14 MeV with annual radiation doses in the range of 20 displacements per atom (dpa). Testing of candidate materials, therefore, requires a high-flux source of high energy neutrons. The problem is that there is currently no high-flux source of neutrons in the energy range above a few MeV. The goal, is therefore, to provide an irradiation facility for use by fusion material scientists in the search for low-activation and damage-resistant materials. An accellerator-based neutron source has been established through a number of international studies and workshops' as an essential step for materials development and testing. The mission of the International Fusion Materials Irradiation Facility (IFMIF) is to provide an accelerator-based, deuterium-lithium (D-Li) neutron source to produce high energy neutrons at sufficient intensity and irradiation volume to test samples of candidate materials up to about a full lifetime of anticipated use in fusion energy reactors. would also provide calibration and validation of data from fission reactor and other accelerator-based irradiation tests. It would generate material- specific activation and radiological properties data, and support the analysis of materials for use in safety, maintenance, recycling, decommissioning, and waste disposal systems

  18. Is There a Relationship between the Usage of Active and Collaborative Learning Techniques and International Students' Study Anxiety?

    Science.gov (United States)

    Khoshlessan, Rezvan

    2013-01-01

    This study was designed to explore the relationships between the international students' perception of professors' instructional practices (the usage of active and collaborative learning techniques in class) and the international students' study anxiety. The dominant goal of this research was to investigate whether the professors' usage of active…

  19. Pharmaceutical wastewater treatment by internal micro-electrolysis--coagulation, biological treatment and activated carbon adsorption.

    Science.gov (United States)

    Wang, Kangle; Liu, Suiqing; Zhang, Qiang; He, Yiliang

    2009-12-01

    Treatment of pharmaceutical wastewater by the combined process of internal micro-electrolysis and coagulation, biological treatment and activated carbon adsorption was studied. Internal micro-electrolysis and coagulation served as the pretreatment for the wastewater before biological treatment to reduce the contaminants' toxicity to microbes and improve the biodegradability of wastewater to guarantee the smooth operation of the biological process. Biological treatment was the main body of the whole process which took an unparalleled role in removing COD (chemical oxygen demand). Activated carbon adsorption was adopted as the post-treatment process to further remove the remaining non-biodegradable particles. Results showed that the removal rates of COD and S2- (sulphide ion) by pretreatment were 66.9% and 98.9%, respectively, and the biodegradability, as measured by the ratio of biodegradable COD to initial COD, of the wastewater was greatly improved from 0.16 +/- 0.02 to 0.41 +/- 0.02. The overall removal rate of COD in the wastewater achieved by this combined treatment process was up to 96%, and the effluent COD met the Chinese tertiary discharge standard (GB 8978-1996).

  20. Pancreatic acini possess endothelin receptors whose internalization is regulated by PLC-activating agents.

    Science.gov (United States)

    Hildebrand, P; Mrozinski, J E; Mantey, S A; Patto, R J; Jensen, R T

    1993-05-01

    Endothelin-1 (ET-1) and ET-3 mRNA have been found in the pancreas. We investigated the ability of ET-1, ET-2, and ET-3 to interact with and alter dispersed rat pancreatic acinar cell function. Radiolabeled ETs bound in a time- and temperature-dependent fashion, which was specific and saturable. Analysis demonstrated two classes of receptors, one class (ETA receptor) had a high affinity for ET-1 but a low affinity for ET-3, and the other class (ETB receptor) had equally high affinities for ET-1 and ET-3. No specific receptor for ET-2 was identified. Pancreatic secretagogues that activate phospholipase C (PLC) inhibited binding of 125I-labeled ET-1 (125I-ET-1) or 125I-ET-3, whereas agents that act through adenosine 3',5'-cyclic monophosphate (cAMP) did not. A23187 had no effect on 125I-ET-1 or 125I-ET-3 binding, whereas the phorbol ester 12-O-tetradecanoylphorbol 13-acetate reduced binding. The effect of cholecystokinin octapeptide (CCK-8) was mediated through its own receptor. Stripping of surface bound ligand studies demonstrated that both 125I-labeled ET-1 and 125I-labeled ET-3 were rapidly internalized. CCK-8 decreased the internalization but did not change the amount of surface bound ligand. Endothelins neither stimulate nor alter changes in enzyme secretion, intracellular calcium, cAMP, or [3H]inositol trisphosphate (IP3). This study demonstrates the presence of ETA and ETB receptors on rat pancreatic acini; occupation of both receptors resulted in rapid internalization, which is regulated by PLC-activating secretagogues. Occupation of either ET receptor did not alter intracellular calcium, cAMP, IP3, or stimulate amylase release.

  1. Managing nuclear knowledge: IAEA activities and international coordination. Asian Network for Education in Nuclear Technology (ANENT)

    International Nuclear Information System (INIS)

    2007-07-01

    This booklet summarizes the main activities being carried out by the IAEA with regard to the Asian Network for Education in Nuclear Technology (ANENT) and other related activities including those completed during the period 2002-2005. It briefly describes the background information on the events leading to the formation of the ANENT; the terms of reference formulated at the second Coordination Committee meeting held in Vietnam, October 2005; and objectives, strategy and other institutional and managerial policies reaffirmed by the members. The attached CD-ROM contains nearly all of the background material in full text, including policy level papers, reports, presentations made by Member States, and meeting summaries

  2. Activities of RILEM Technical Committee: Internal Curing of Concrete and Anticipated Research

    DEFF Research Database (Denmark)

    Kovler, Konstantin; Jensen, Ole Mejlhede

    in the domain. To account for the different practices and different standards around the world, the TC included representatives from three different world regions: Europe, North America and Asia. Totally more than 30 members from 17 countries contributed in the committee work. Some of them serve in parallel...... of Concrete” of the International Union of Laboratories and Experts in Construction Materials, Systems and Structures (RILEM). The authors of this short communication served as a chair (K. Kovler) and secretary (O.M. Jensen) of the TC. The regular and corresponding members were acknowledged RILEM experts...

  3. The Third International Genomic Medicine Conference (3rd IGMC, 2015: overall activities and outcome highlights

    Directory of Open Access Journals (Sweden)

    Muhammad Abu-Elmagd

    2016-10-01

    Full Text Available Abstract The Third International Genomic Medicine Conference (3rd IGMC was organised by the Centre of Excellence in Genomic Medicine Research (CEGMR at the King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia (KSA. This conference is a continuation of a series of meetings, which began with the first International Genomic Medicine Conference (1st IGMC, 2011 followed by the second International Genomic Medicine Conference (2nd IGMC, 2013. The 3rd IGMC meeting presented as a timely opportunity to bring scientists from across the world to gather, discuss, and exchange recent advances in the field of genomics and genetics in general as well as practical information on using these new technologies in different basic and clinical applications. The meeting undoubtedly inspired young male and female Saudi researchers, who attended the conference in large numbers, as evidenced by the oversubscribed oral and poster presentations. The conference also witnessed the launch of the first content for npj Genomic Medicine, a high quality new journal was established in partnership by CEGMR with Springer Nature and published as part of the Nature Partner Journal series. Here, we present a brief summary report of the 2-day meeting including highlights from the oral presentations, poster presentations, workshops, poster prize-winners and comments from the distinguished scientists.

  4. A unified internal model theory to resolve the paradox of active versus passive self-motion sensation.

    Science.gov (United States)

    Laurens, Jean; Angelaki, Dora E

    2017-10-18

    Brainstem and cerebellar neurons implement an internal model to accurately estimate self-motion during externally generated ('passive') movements. However, these neurons show reduced responses during self-generated ('active') movements, indicating that predicted sensory consequences of motor commands cancel sensory signals. Remarkably, the computational processes underlying sensory prediction during active motion and their relationship to internal model computations during passive movements remain unknown. We construct a Kalman filter that incorporates motor commands into a previously established model of optimal passive self-motion estimation. The simulated sensory error and feedback signals match experimentally measured neuronal responses during active and passive head and trunk rotations and translations. We conclude that a single sensory internal model can combine motor commands with vestibular and proprioceptive signals optimally. Thus, although neurons carrying sensory prediction error or feedback signals show attenuated modulation, the sensory cues and internal model are both engaged and critically important for accurate self-motion estimation during active head movements.

  5. IAEA activities in support of the international programmes to return fresh and spent research reactor nuclear fuel to the conuntry of origin

    International Nuclear Information System (INIS)

    Adelgang, P.; Tozser, S.; Marshall, F.; Borio di Tigliole, A.

    2017-01-01

    The IAEA has been involved for more than thirty years in supporting international nuclear non-proliferation efforts associated with reducing the amount of Highly Enriched Uranium (HEU), whose enrichment is ≥ 20% in 235U, in international commerce. In particular, IAEA projects and activities have directly supported the two main international efforts to return fresh and spent HEU research reactor fuel to the country where it was originally enriched: the United States Foreign Research Reactor Spent Nuclear Fuel (FRRSNF) Acceptance Programme and the United States-IAEA-Russian Federation tripartite initiative known as the Russian Research Reactor Fuel Return (RRRFR) Programme. This report gives an account of IAEA efforts in support of both programmes including a historical overview of fuel return shipments and a brief description of associated cooperation activities carried out by the IAEA. [es

  6. Highly active antiretroviral therapy including protease inhibitors does not confer a unique CD4 cell benefit. The AVANTI and INCAS Study Groups.

    Science.gov (United States)

    2000-07-07

    To determine if triple combination therapy, particularly including HIV protease inhibitors (PI), confers an unique immunological benefit that is independent of reductions of plasma viral load (pVL). The correlation between changes from baseline in CD4 cell count and pVL was examined at all time points up to 52 weeks in three randomized clinical trials (AVANTI-2, AVANTI-3 and INCAS) that compared dual nucleoside therapy with triple combination therapy. Individual pVL and CD4 cell counts changes from baseline were entered into multivariate linear regression models for patients receiving double therapy and for those receiving triple therapy including a PI and/or a non-nucleoside reverse transcriptase inhibitor (NNRTI), and the null hypothesis was tested. After 52 weeks of therapy, the relationship between changes from baseline CD4 cell count and pVL was independent of whether patients were assigned double or triple therapy (P = 0.23 and 0.69 for intercept and slope, respectively), or whether patients were assigned triple therapy including a PI or triple therapy including an NNRTI (P = 0.92 and 0.95, respectively). Less than 5% of patients ever had 'discordant' increases in both CD4 cell count and pVL compared with baseline, and this proportion was unrelated to the class of therapy used. 'Discordant' decreases from baseline in both parameters were observed in up to 35% of individuals. The correlation between pVL and CD4 cell count changes from baseline improved over time on therapy, regardless of the therapeutic regimen involved. The data provide no evidence for a CD4 cell count benefit of highly active antiretroviral therapy (HAART) unique to triple therapy or PI-containing regimens.

  7. Comparison of the Physical Activity and Sedentary Behaviour Assessment Questionnaire and the Short-Form International Physical Activity Questionnaire: An Analysis of Health Survey for England Data.

    Directory of Open Access Journals (Sweden)

    Shaun Scholes

    Full Text Available The Physical Activity and Sedentary Behaviour Assessment Questionnaire (PASBAQ, used within the Health Survey for England (HSE at 5-yearly intervals, is not included annually due to funding and interview-length constraints. Policy-makers and data-users are keen to consider shorter instruments such as the Short-form International Physical Activity Questionnaire (IPAQ for the annual survey. Both questionnaires were administered in HSE 2012, enabling comparative assessment in a random sample of 1252 adults.Relative agreement using prevalence-adjusted bias-adjusted Kappa (PABAK statistics was estimated for: sufficient aerobic activity (moderate-to-vigorous physical activity [MVPA] ≥150 minutes/week; inactivity (MVPA<30 minutes/week; and excessive sitting (≥540 minutes/weekday. Cross-sectional associations with health outcomes were compared across tertiles of MVPA and tertiles of sitting time using logistic regression with tests for linear trend.Compared with PASBAQ data, IPAQ-assessed estimates of sufficient aerobic activity and inactivity were higher and lower, respectively; estimates of excessive sitting were higher. Demographic patterns in prevalence were similar. Agreement using PABAK statistics was fair-to-moderate for sufficient aerobic activity (0.32-0.49, moderate-to-substantial for inactivity (0.42-0.74, and moderate-to-substantial for excessive sitting (0.49-0.75. As with the PASBAQ, IPAQ-assessed MVPA and sitting each showed graded associations with mental well-being (women: P for trend = 0.003 and 0.004, respectively and obesity (women: P for trend = 0.007 and 0.014, respectively.Capturing habitual physical activity and sedentary behaviour through brief questionnaires is complex. Differences in prevalence estimates can reflect differences in questionnaire structure and content rather than differences in reported behaviour. Treating all IPAQ-assessed walking as moderate-intensity contributed to the differences in prevalence estimates

  8. Fluconazole-Pyridoxine Bis-Triazolium Compounds with Potent Activity against Pathogenic Bacteria and Fungi Including Their Biofilm-Embedded Forms

    Directory of Open Access Journals (Sweden)

    Marsel R. Garipov

    2017-01-01

    Full Text Available Two novel quaternary ammonium salts, bis-triazolium derivatives of fluconazole and pyridoxine, were synthesized by reaction of fluconazole with pyridoxine-based synthetic intermediates. The leading compound demonstrated pronounced antimycotic and antibacterial in vitro activity, comparable to or exceeding that of the reference antifungal (fluconazole, terbinafine and antibacterial/antiseptic (miramistin, benzalkonium chloride agents. In contrast to many antimicrobials, the leading compound was also active against biofilm-embedded staphylococci and Escherichia coli. While no biofilm structure destruction occurred, all compounds were able to diffuse into the matrix and reduce the number of colony-forming units by three orders of magnitude at 16 × MBC. The leading compound was significantly less toxic than miramistin and benzalkonium chloride and more toxic than the reference antifungal drugs. The obtained results make the described chemotype a promising starting point for the development of new broad-spectrum antimicrobial therapies with powerful effect on fungal and bacterial pathogens including their biofilm-embedded forms.

  9. Summary of international energy research and development activities, 1974--1976

    International Nuclear Information System (INIS)

    1977-11-01

    This directory includes information covering 3017 ongoing and recently completed energy research projects conducted in Canada, Italy, the Federal Republic of Germany, France, The Netherlands, the United Kingdom, Denmark, Sweden, Israel, and 18 other countries. This information was registered with the Smithsonian Science Information Exchange (SSIE) by supporting organizations in the nine countries listed and by international organizations such as the International Atomic Energy Agency. All narrative information presented in the directory and, in some cases, organization names were translated into English. In addition to the title and text of project summaries, the directory contains the following indexes: Subject Index, Investigator Index, Performing Organization Index, and Supporting Organization Index. To reflect particular facets of energy research, the Subject Index is cross-referenced. The Subject Index is based upon the SSIE classification system, which organizes index terms in hierarchies to relate groups of narrow subject areas within broad areas. The following types of energy information are included: organic sources of energy (gas and oil; coal; peat, hydrocarbons, and nonfossil organic sources); thermonuclear energy and plasma physics; fission sources and energy production (reactor fuels assemblies and fuel management; reactor materials; reactor components; reactor thermodynamics, thermohydraulics, and mechanics; reactor safety and control; reactor testing, operations, and analysis; reactor and nuclear physics; uranium exploration and mining; reactors--general); geophysical energy sources (geothermal, hydro, solar, wave, and wind); conversion technology; environmental aspects of energy conversion and use; transport and transmission of energy; energy utilization and conservation; and energy systems and other energy research

  10. Activity of Posaconazole and Other Antifungal Agents against Mucorales Strains Identified by Sequencing of Internal Transcribed Spacers▿

    Science.gov (United States)

    Alastruey-Izquierdo, Ana; Castelli, Maria Victoria; Cuesta, Isabel; Monzon, Araceli; Cuenca-Estrella, Manuel; Rodriguez-Tudela, Juan Luis

    2009-01-01

    The antifungal susceptibility profiles of 77 clinical strains of Mucorales species, identified by internal transcribed spacer sequencing, were analyzed. MICs obtained at 24 and 48 h were compared. Amphotericin B was the most active agent against all isolates, except for Cunninghamella and Apophysomyces isolates. Posaconazole also showed good activity for all species but Cunninghamella bertholletiae. Voriconazole had no activity against any of the fungi tested. Terbinafine showed good activity, except for Rhizopus oryzae, Mucor circinelloides, and Rhizomucor variabilis isolates. PMID:19171801

  11. Activity of posaconazole and other antifungal agents against Mucorales strains identified by sequencing of internal transcribed spacers.

    Science.gov (United States)

    Alastruey-Izquierdo, Ana; Castelli, Maria Victoria; Cuesta, Isabel; Monzon, Araceli; Cuenca-Estrella, Manuel; Rodriguez-Tudela, Juan Luis

    2009-04-01

    The antifungal susceptibility profiles of 77 clinical strains of Mucorales species, identified by internal transcribed spacer sequencing, were analyzed. MICs obtained at 24 and 48 h were compared. Amphotericin B was the most active agent against all isolates, except for Cunninghamella and Apophysomyces isolates. Posaconazole also showed good activity for all species but Cunninghamella bertholletiae. Voriconazole had no activity against any of the fungi tested. Terbinafine showed good activity, except for Rhizopus oryzae, Mucor circinelloides, and Rhizomucor variabilis isolates.

  12. Comparison of the Physical Activity and Sedentary Behaviour Assessment Questionnaire and the Short-Form International Physical Activity Questionnaire: An Analysis of Health Survey for England Data

    Science.gov (United States)

    Scholes, Shaun; Bridges, Sally; Ng Fat, Linda; Mindell, Jennifer S.

    2016-01-01

    Background The Physical Activity and Sedentary Behaviour Assessment Questionnaire (PASBAQ), used within the Health Survey for England (HSE) at 5-yearly intervals, is not included annually due to funding and interview-length constraints. Policy-makers and data-users are keen to consider shorter instruments such as the Short-form International Physical Activity Questionnaire (IPAQ) for the annual survey. Both questionnaires were administered in HSE 2012, enabling comparative assessment in a random sample of 1252 adults. Methods Relative agreement using prevalence-adjusted bias-adjusted Kappa (PABAK) statistics was estimated for: sufficient aerobic activity (moderate-to-vigorous physical activity [MVPA] ≥150minutes/week); inactivity (MVPAactivity and inactivity were higher and lower, respectively; estimates of excessive sitting were higher. Demographic patterns in prevalence were similar. Agreement using PABAK statistics was fair-to-moderate for sufficient aerobic activity (0.32–0.49), moderate-to-substantial for inactivity (0.42–0.74), and moderate-to-substantial for excessive sitting (0.49–0.75). As with the PASBAQ, IPAQ-assessed MVPA and sitting each showed graded associations with mental well-being (women: P for trend = 0.003 and 0.004, respectively) and obesity (women: P for trend = 0.007 and 0.014, respectively). Conclusions Capturing habitual physical activity and sedentary behaviour through brief questionnaires is complex. Differences in prevalence estimates can reflect differences in questionnaire structure and content rather than differences in reported behaviour. Treating all IPAQ-assessed walking as moderate-intensity contributed to the differences in prevalence estimates. PASBAQ data will be used for population surveillance every 4 to 5 years. The current version of the Short-form IPAQ was included in HSE 2013–14 to enable more frequent assessment of physical activity and sedentary behaviour; a modified version with different item-ordering and

  13. Recent International R&D Activities in the Extraction of Uranium from Seawater

    Energy Technology Data Exchange (ETDEWEB)

    Rao, Linfeng

    2010-03-15

    A literature survey has been conducted to collect information on the International R&D activities in the extraction of uranium from seawater for the period from the 1960s till the year of 2010. The reported activities, on both the laboratory scale bench experiments and the large scale marine experiments, were summarized by country/region in this report. Among all countries where such activities have been reported, Japan has carried out the most advanced large scale marine experiments with the amidoxime-based system, and achieved the collection efficiency (1.5 g-U/kg-adsorbent for 30 days soaking in the ocean) that could justify the development of industrial scale marine systems to produce uranium from seawater at the price competitive with those from conventional uranium resources. R&D opportunities are discussed for improving the system performance (selectivity for uranium, loading capacity, chemical stability and mechanical durability in the sorption-elution cycle, and sorption kinetics) and making the collection of uranium from seawater more economically competitive.

  14. Recent International R and D Activities in the Extraction of Uranium from Seawater

    International Nuclear Information System (INIS)

    Rao, Linfeng

    2010-01-01

    A literature survey has been conducted to collect information on the International R and D activities in the extraction of uranium from seawater for the period from the 1960s till the year of 2010. The reported activities, on both the laboratory scale bench experiments and the large scale marine experiments, were summarized by country/region in this report. Among all countries where such activities have been reported, Japan has carried out the most advanced large scale marine experiments with the amidoxime-based system, and achieved the collection efficiency (1.5 g-U/kg-adsorbent for 30 days soaking in the ocean) that could justify the development of industrial scale marine systems to produce uranium from seawater at the price competitive with those from conventional uranium resources. R and D opportunities are discussed for improving the system performance (selectivity for uranium, loading capacity, chemical stability and mechanical durability in the sorption-elution cycle, and sorption kinetics) and making the collection of uranium from seawater more economically competitive.

  15. Marine energy consumption, national economic activity, and greenhouse gas emissions from international shipping

    International Nuclear Information System (INIS)

    Chang, Ching-Chih

    2012-01-01

    The causal relationships among marine energy consumption, greenhouse gas emissions from international shipping, and economic growth for Kyoto Protocol Annex I countries for the period of 1990 to 2006 are discussed. The real gross domestic product is used as a proxy for economic activity. The United States is also discussed because it was the main global polluter before 2006. The co-integration methodology and an error-correction model are used to examine the causal relationships. The empirical results show that marine energy consumption and GDP are the main factors of increased GHG emissions in the short-run, and that economic activity significantly increased emissions in the long-run. Emissions from shipping are more closely related to marine energy consumption than to economic activity. Hence, policies for mitigating greenhouse gas emissions from marine shipping need to focus on greater energy efficiency in the design of ship engines and hulls. - Highlights: ► Energy consumption and GDP are the main causes to increased GHG emissions in the shipping industry. ► Emissions from shipping are more closely related to energy consumption than to GDP. ► Policies to mitigate GHG emissions from shipping industry should focus on the engine and hull design.

  16. St Petersburg Business Information Centres and Their Role in Increasing the Efficiency of International Business Activities

    Directory of Open Access Journals (Sweden)

    Bazhenov Yu.

    2014-08-01

    Full Text Available The Ministry of Foreign Affairs of the Russian Federation acknowledges the significant contribution of regions to the development of the state’s foreign policy. An increase in innovative production, a commitment to achieve complete import substitution, and the development of measures to promote non-raw material export are the principal objectives established by the state for its regions. The current trends in world economy and the geopolitical situation formulate new goals and objectives for regions and suggest the creation of innovative and universal mechanisms to increase the efficiency of international economic activities, promotion of a positive image of Saint Petersburg and other regions of the Russian Northwest. The article analyses the activities of Saint Petersburg business information centres abroad, similar experience of other Russian regions, and prerequisites for reforming the institution of regional offices abroad. In the course of the study, new theoretical and methodological questions as to improving the regulatory framework for development and functioning of Russian regional offices abroad, the use of public-private partnership mechanism in foreign economic activities and information technologies of positive image promotion were formulated.

  17. Physical activity in patients with stable coronary heart disease: an international perspective.

    Science.gov (United States)

    Stewart, Ralph; Held, Claes; Brown, Rebekkah; Vedin, Ola; Hagstrom, Emil; Lonn, Eva; Armstrong, Paul; Granger, Christopher B; Hochman, Judith; Davies, Richard; Soffer, Joseph; Wallentin, Lars; White, Harvey

    2013-11-01

    Despite the known benefits of regular exercise, the reasons why many coronary heart disease (CHD) patients engage in little physical activity are not well understood. This study identifies factors associated with low activity levels in individuals with chronic CHD participating in the STABILITY study, a global clinical outcomes trial evaluating the lipoprotein phospholipaseA2 inhibitor darapladib. Prior to randomization, 15 486 (97.8%) participants from 39 countries completed a lifestyle questionnaire. Total physical activity was estimated from individual subject self-reports of hours spend each week on mild, moderate, and vigorous exercise, corresponding approximately to 2, 4, and 8 METS, respectively. Multivariate logistic regression evaluated clinical and demographic variables for the lowest compared with higher overall exercise levels, and for individuals who decreased rather than maintained or increased activity since diagnosis of CHD. The least active 5280 subjects (34%) reported exercise of ≤ 24 MET.h/week. A total of 7191 subjects (46%) reported less exercise compared with before diagnosis of CHD. The majority of participants were either 'not limited' or 'limited a little' walking 100 m (84%), climbing one flight of stairs (82%), or walking 1 km/1/2; mile (68%), and physical activity and decreasing exercise after diagnosis of CHD included more co-morbid conditions, poorer general health, fewer years of education, race, and country (P physical activity was only partly explained by cardiovascular symptoms. Potentially modifiable societal and health system factors are important determinants of physical inactivity in patients with chronic CHD.

  18. An overview of the International Electrotechnical Commission's activities on quality assurance in diagnostic radiology

    International Nuclear Information System (INIS)

    Julius, H.W.; Ammers, H. van; Henshaw, E.T.

    1989-01-01

    In 1981, the International Electrotechnical Commission Sub-committee 62B set up a Working Group (WG 10) to deal with quality assurance in diagnostic X-ray departments and, more specifically, to develop international standards describing procedures to test the constancy of parameters of diagnostic X-ray installations. Since then, the working group has produced a report on General Aspects of Quality Assurance in Diagnostic X-ray Departments and four draft standards on specific topics, while seven more documents are in advanced drafting stage. Several others are presently under consideration. According to the approach adopted by the Working Group, these documents are meant to assist in establishing quality assurance programmes in hospitals and provide guidance on how to perform the tests and interpret their results. This paper reveals the general philosophy behind the activities of the Working Group as well as some details of the standard produced so far, with emphasis on the physical parameters of diagnostic X-ray installations and their proposed criteria for satisfactory performance. (author)

  19. Nuclear Energy Gradients for Internally Contracted Complete Active Space Second-Order Perturbation Theory: Multistate Extensions.

    Science.gov (United States)

    Vlaisavljevich, Bess; Shiozaki, Toru

    2016-08-09

    We report the development of the theory and computer program for analytical nuclear energy gradients for (extended) multistate complete active space perturbation theory (CASPT2) with full internal contraction. The vertical shifts are also considered in this work. This is an extension of the fully internally contracted CASPT2 nuclear gradient program recently developed for a state-specific variant by us [MacLeod and Shiozaki, J. Chem. Phys. 2015, 142, 051103]; in this extension, the so-called λ equation is solved to account for the variation of the multistate CASPT2 energies with respect to the change in the amplitudes obtained in the preceding state-specific CASPT2 calculations, and the Z vector equations are modified accordingly. The program is parallelized using the MPI3 remote memory access protocol that allows us to perform efficient one-sided communication. The optimized geometries of the ground and excited states of a copper corrole and benzophenone are presented as numerical examples. The code is publicly available under the GNU General Public License.

  20. Status of international environmental remediation activities: A report from the Prague conference

    International Nuclear Information System (INIS)

    Slate, S.C.; Thornhill, C.K.; Allen, R.E.

    1993-10-01

    The Prague Conference on nuclear waste management and environmental remediation provided extensive interchange of ideas and insight into new technologies and management approaches throughout the world. A variety of environmental remediation technologies have potential application to Department of Energy facilities; others illustrate pitfalls to be avoided. This paper presents the highlights from the first environmental remediation (ER) technical program in the American Society of Mechanical Engineers' series of international nuclear waste management conferences. This program covers ER technologies, decontamination and decommissioning (D ampersand D) technologies and experience, ER site characterization and modeling, management of and results from actual clean up actions, and data on several major international environmental problems. Focusing on direct benefits to the Department of Energy's (DOE) ER Program, this paper summarizes pertinent technical information, identifies useful technical papers, lists key technical contacts, and identifies specific actions to obtain additional information. US attendance at meetings like this is normally quite limited compared to attendance at North American meetings. The purpose of this paper then is to increase general awareness of this meeting in US technical circles and to broadly disseminate key information to US ER programs and contractors. To do this, the paper is organized to present background information on the conference itself, document the beneficial technical information, and outline ongoing information exchange activities

  1. The IAEA international project on innovative nuclear reactors and fuel cycles (INPRO): current and future activities

    International Nuclear Information System (INIS)

    Kupitz, J.; Depisch, F.; Kuznetsov, V.

    2004-01-01

    Upon resolutions of the IAEA General Conference in 2000, the IAEA initiated International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO). The objective of INPRO, which comprises two phases, is to support sustainable deployment and use of nuclear technology to meet the global energy needs in the next 50 years and beyond. During Phase I, work is subdivided into two sub phases. Phase 1A focused on determining user requirements in the areas of economics, environment, safety, proliferation resistance, and recommendations in the area of so-called crosscutting issues, which are legal, institutional, and infrastructure issues accompanying the deployment of nuclear power, and is targeted at developing a methodology and guidelines for the assessment of various nuclear reactor and fuel cycle concepts and approaches. Phase 1A was finalised in June 2003 with its results now available as IAEA TECDOC-1362. Phase 1B has started in July 2003. During this phase interested Member States are performing case studies to validate the INPRO methodology and, later on, to assess selected innovative nuclear energy systems using the updated INPRO methodology. In accordance with the INPRO Terms of Reference, after successful completion of Phase I, Phase II may be initiated to examine the feasibility of commencing international projects on innovative nuclear energy systems. The paper contains a description of the current and future activities of INPRO and summarizes the outcome of the project.(author)

  2. Regulatory inspection activities related to inspection planning, plant maintenance and assessment of safety. Proceedings of an international workshop

    Energy Technology Data Exchange (ETDEWEB)

    Van Binnebeek, J. J. [AIB-Vincotte Nuclear - AVN, Avenue du Roi, 157, B-1060 Brussels (Belgium); Aubrey, Richard; Grandame, Melvyn [Atomic Energy Control Board - AECB, P.O. Box 1046, Station B, 280 Slater Street, Ottawa, Ontario K1P 5S9 (Canada); Aro, Ilari [Finnish Centre for Radiation and Nuclear Safety - STUK, P.O. Box 14, FIN-00881 Helsinki (Finland); Balloffet, Yves [DRIRE Rhone Alpes, 146, rue Pierre Corneille, 69426 Lyon CEDEX 03 (France); Klonk, Hartmut [Bundesamt fuer Strahlenschutz - BfS, Federal Office for Radiation Protection, Postbox 10 01 49, 38201 Salzgitter 1 (Germany); Manzella, Pietro [A.N.P.A., Via V. Brancati, 48, 1-00144 Roma EUR (Italy); Koizumi, Hiroyoshi [Tech. Stan. Dept. - JAPEIC, Shin-Toranomon Bldg., 1-5-11, Akasaka, Minato-ku, Tokyo 107 (Japan); Bouvrie, E.C. des [Ministry of Social Affairs and Employment, Nuclear Safety Dept. KFD, P.O. Box 90804, 2509 LV The Hague (Netherlands); Forsberg, Staffan [Swedish Nuclear Power Inspectorate - SKI, Klarabergsviadukten 90, S-10658 Stockholm (Sweden); Lang, Hans-Guenter [Section Plant Coordination and Inspection, Swiss Federal Nuclear Safety Inspectorate - HSK, CH-5232 Villigen-HSK (Switzerland); Mehew, Robert; Warren, Thomas; Woodhouse, Paul [Health and Safety Executive - NII, St. Peter' s House, Balliol Road, Bootle, Merseyside L20 3LZ (United Kingdom); Gallo, Robert M. [Special Inspection Branch, US Nuclear Regulatory Commission - US NRC, Mail Stop 0-9A1, Washington, DC 20555 (United States); Campbell, Rob [International Atomic Energy Agency - IAEA, P.O. Box 100, A-1400 Vienna (International Atomic Energy Agency (IAEA))

    1997-07-01

    The NEA Committee on Nuclear Regulatory Activities (CNRA) believes that an essential factor in ensuring the safety of nuclear installations is the continuing exchange and analysis of technical information and data. To facilitate this exchange the Committee has established Working Groups and Groups of Experts in specialised topics. CNRA believes that safety inspections are a major element in the regulatory authority's efforts to ensure the safe operation of nuclear facilities. Considering the importance of these issues, the Committee has established a special Working Group on Inspection Practices (WGIP). The purpose of WGIP, is to facilitate the exchange of information and experience related to regulatory safety inspections between CNRA Member countries. This was the 3. international workshop held by the WGIP on regulatory inspection activities. The focus of this workshop was on 3 main topics; Inspection Planning, Plant Maintenance and Assessment of Safety. This document presents the proceedings from the workshop, including: workshop programme, results and conclusions, papers and presentations and the list of participants. The main purpose of the Workshop is to provide a forum of exchange of information on the regulatory inspection activities.

  3. Regulatory inspection activities related to inspection planning, plant maintenance and assessment of safety. Proceedings of an international workshop

    International Nuclear Information System (INIS)

    Van Binnebeek, J.J.; Aubrey, Richard; Grandame, Melvyn; Aro, Ilari; Balloffet, Yves; Klonk, Hartmut; Manzella, Pietro; Koizumi, Hiroyoshi; Bouvrie, E.C. des; Forsberg, Staffan; Lang, Hans-Guenter; Mehew, Robert; Warren, Thomas; Woodhouse, Paul; Gallo, Robert M.; Campbell, Rob; )

    1997-01-01

    The NEA Committee on Nuclear Regulatory Activities (CNRA) believes that an essential factor in ensuring the safety of nuclear installations is the continuing exchange and analysis of technical information and data. To facilitate this exchange the Committee has established Working Groups and Groups of Experts in specialised topics. CNRA believes that safety inspections are a major element in the regulatory authority's efforts to ensure the safe operation of nuclear facilities. Considering the importance of these issues, the Committee has established a special Working Group on Inspection Practices (WGIP). The purpose of WGIP, is to facilitate the exchange of information and experience related to regulatory safety inspections between CNRA Member countries. This was the 3. international workshop held by the WGIP on regulatory inspection activities. The focus of this workshop was on 3 main topics; Inspection Planning, Plant Maintenance and Assessment of Safety. This document presents the proceedings from the workshop, including: workshop programme, results and conclusions, papers and presentations and the list of participants. The main purpose of the Workshop is to provide a forum of exchange of information on the regulatory inspection activities

  4. Outreach activities on light science and technology at TecnOpto-UMH during the International Year of Light

    Science.gov (United States)

    Sánchez-López, María. del Mar; García-Martínez, Pascuala; Espinosa, Rocío.; Carnicer, Jesús; Arias, Julia; Moreno, Ignacio

    2016-09-01

    TecnOpto is a group of researchers and teachers with interests in Optics and Photonics, located at the University Miguel Hernández (UMH) of Elche (Spain). Here we report on our outreach activities carried out during the International Year of Light - 2015. They include experiments and demonstrations at elementary and secondary schools, seminars and exhibitions at the university, and the activity named the "Classroom for the Experience", targeted to elder people. We also report on our participation in the science fair in Elche and in the launching of "the Room of Light", a complete new section of the MUDIC science museum devoted to light and optics. MUDIC is located in the UMH campus of Orihuela, and receives visitors from all over the region, mainly young students from elementary and secondary schools. Finally, we report on the exhibition "Women in Light Science and Light Technologies" which was organized by members of our group in collaboration with RSEF - the Spanish Royal Physical Society and SEDOPTICA - the Spanish Optical Society and sponsored by SPIE. This exhibition consisting of twelve posters on relevant women scientists was inaugurated in the XI Spanish Meeting on Optics and has travelled around many universities and cultural centers in Spain. A summary of the contents, participation and developing of all these activities is presented.

  5. Report of International NanoSPD Steering Committee and statistics on recent NanoSPD activities

    International Nuclear Information System (INIS)

    Valiev, R Z; Langdon, T G

    2014-01-01

    Abstract. The Université de Lorraine in Metz, France, is the selected site for the 6th International Conference on Nanomaterials by Severe Plastic Deformation (NanoSPD6) following a series of five earlier conferences. This introductory paper reports on several major developments in NanoSPD activities as well as on very recent NanoSPD citation data which confirm the continued growth and expansion of this important research area. Close attention is given to the topics of workshops, conferences and seminars organized during these last three years as well as on books and reviews published prior to the NanoSPD6 conference. A special concern of the committee is in introducing and discussing the appropriate terminology to be applied in this new field of materials science and engineering

  6. Internal Porosity of Mineral Coating Supports Microbial Activity in Rapid Sand Filters for Groundwater Treatment

    DEFF Research Database (Denmark)

    Gülay, Arda; Tatari, Karolina; Musovic, Sanin

    2014-01-01

    of the filter material. The volumetric NH4+ removal rate also increased with the degree of mineral coating. Consistently, bacterial 16S rRNA and amoA abundances positively correlated with increased mineral coating levels. Microbial colonization could be visualized mainly within the outer periphery (60.6 ± 35......, and abundance of microbiota. This study reveals that a mineral coating can positively affect the colonization and activity of microbial communities in rapid sand filters. To understand this effect, we investigated the abundance, spatial distribution, colonization, and diversity of all and of nitrifying...... prokaryotes in filter material with various degrees of mineral coating. We also examined the physical and chemical characteristics of the mineral coating. The amount of mineral coating correlated positively with the internal porosity, the packed bulk density, and the biologically available surface area...

  7. Characteristics of the innovation activities of firms in Europe: a critical review of international differences

    Directory of Open Access Journals (Sweden)

    Vokoun Marek

    2017-09-01

    Full Text Available A sample of 18 papers and 32 data sets revealed 210,404 firm level observations about European firms making decisions about innovation. A total of 66,965 observations describe activities of innovators between 1986 and 2008. This paper used a basic literature review to assess properties of innovation among quite rare full CDM (Crépon, Duguet, and Mairesse papers. This study compared results from two systems of estimation and showed that both international and regional comparisons are rather problematic because of different definitions of innovation variables and data set representativeness. On average, a typical firm that engaged in innovation was a large firm competing in international markets in the sample of firms with 20+ employees. Smaller firms, however, invested more in research and development (R&D and no linear relationship was found for output characteristics. Cooperation on R&D projects increased overall innovation intensity. There is strong evidence that public funding had an ambiguous effect on R&D spending and no additional effect on innovation output on average. This output measured by sales from innovated goods and services was on average in a positive relationship with labour productivity; however, a detailed view suggested this effect was present only in product innovation. In this paper, it is shown that results of innovation studies cannot be compared or used in research without deeper analysis of the data sample (micro companies, industries, active firms, entrants etc., dependent variable (innovator, R&D expenditures, sales, productivity, new product, new service etc. and the baseline company that is defined by independent variables.

  8. Simulation with Phast of the pore water chemistry experiment results (Mont Terri Url, Switzerland), including transport, thermodynamics, kinetics, and biological activity

    International Nuclear Information System (INIS)

    Tournassat, C.; Gaucher, E.; Pearson, F.J.; Mettler, S.; Wersin, P.

    2005-01-01

    Full text of publication follows: The Pore water Chemistry (PC-)experiment was initially designed to determine the processes that control the redox properties of pore water in the Opalinus Clay at the Mont Terri URL. However, changes in isotopic data and chemical parameters such as pH, alkalinity, dissolved methane, acetate and sulphate concentrations indicated unexpected microbial activity. The origin of the bacteria is not clear. In the light of published data, an indigenous origin cannot be ruled out. A combined biological and reactive transport model has been developed with the parallel PHAST software to simulate the processes that determine pore water chemistry. The influence of bacterial activity on the system is successfully modelled by considering different reaction pathways scenarios including aceto-genesis, methano-genesis, and methane/acetate oxidation coupled to sulphate reduction. Several conclusions can be clearly stated in the light of the simulation results: - The measured redox potentials (redox electrode) are in line with the S(-II)/S(+VI) redox system. - In the undisturbed pore water, S(-II) and S(+VI) activities are controlled by a mineral assemblage containing pyrite and a Fe carbonate (siderite or ankerite). pH is buffered by mineral phases and SO 4 2- concentration is inherited from the marine sedimentary rock. - Some local redox potentials in the sedimentary rock do not correspond to the measured redox potential; for instance, organic matter/HCO 3 - and CH 4 /HCO 3 - systems are not at equilibrium with the measured redox potential. - Redox disequilibrium can be exploited by micro-organisms as a source of energy for their metabolism. In this experiment CH 4 , acetate and other organic acids were produced and SO 4 2- was reduced to HS - . The redox properties of the system are then governed by kinetics rather than by thermodynamic equilibrium. The unexpected persistence of acetate in the borehole water is one of the consequences of these

  9. Environmental toxin acrolein alters levels of endogenous lipids, including TRP agonists: A potential mechanism for headache driven by TRPA1 activation

    Directory of Open Access Journals (Sweden)

    Emma Leishman

    2017-01-01

    Full Text Available Exposure to airborne toxins can trigger headaches, but the mechanisms are not well understood. Some environmental toxins, such as acrolein, activate transient receptor potential ankyrin 1 (TRPA1, a receptor involved in pain sensation that is highly expressed in the trigeminovascular system. It has been shown in rat models that repeated exposure to acrolein induces trigeminovascular sensitization to both TRPA1 and TRP vanilloid 1 (TRPV1 agonists, a phenomenon linked to headache. In this study, we test the hypothesis that the sensitization of trigeminovascular responses in rats after acrolein exposure via inhalation is associated with changes in levels of endogenous lipids, including TRPV1 agonists, in the trigeminal ganglia, trigeminal nucleus, and cerebellum. Lipidomics analysis of 80 lipids was performed on each tissue after acute acrolein, chronic acrolein, or room air control. Both acute and chronic acrolein exposure drove widespread alterations in lipid levels. After chronic acrolein exposure, levels of all 6 N-acyl ethanolamines in the screening library, including the endogenous cannabinoid and TRPV1 agonist, N-arachidonoyl ethanolamine, were elevated in trigeminal tissue and in the cerebellum. This increase in TRPV1 ligands by acrolein exposure may indicate further downstream signaling, in that we also show here that a combination of these TRPV1 endogenous agonists increases the potency of the individual ligands in TRPV1-HEK cells. In addition to these TRPV1 agonists, 3 TRPV3 antagonists, 4 TRPV4 agonists, and 25 orphan lipids were up and down regulated after acrolein exposure. These data support the hypothesis that lipid signaling may represent a mechanism by which repeated exposure to the TRPA1 agonist and environmental toxin, acrolein, drives trigeminovascular sensitization. Keywords: Lipidomics, Endogenous cannabinoid, TRPA1, TRPV1, Lipoamine, Acrolein, Migraine

  10. Evaluation of selected financial aspects in the Czech Republic: a research study about the international activities of Czech business

    Directory of Open Access Journals (Sweden)

    Meixnerová Lucie

    2017-01-01

    Full Text Available The paper deals with the evaluation of selected financial aspects of micro, small and medium-sized enterprises in the Czech conditions in the context of the international activities. The aim of this paper is to identify and evaluate whether there are dependencies between these indicators in the context of domestic and international environment by using selected methods. In the article are evaluated the results of our own survey of the development of micro, small and medium enterprises in the years 2009–2016, with a total of 650 respondents (SMEs. The author calculates and describes traditional financial indicators and international activities represented by ROA, ROE and ROC. Research findings confirm that the companies operating in the Czech environment show higher growth at those micro-enterprises without international activities. Companies operating in an international environment shown stronger growth among medium-sized businesses. This is due to the benefits of international cooperation, the size and development of the company, and the growing influence of the international environment on business entities.

  11. Aligning Physical Activity Measures with the International Classification of Functioning, Disability and Health Framework for Childhood Disability

    Science.gov (United States)

    Ross, Samantha Mae; Case, Layne; Leung, Willie

    2016-01-01

    The introduction of the International Classification of Functioning, Disability and Health has placed emphasis on framing health behavior as a multidimensional construct. In relation to childhood physical activity, this encompasses dimensions of functional performance, activity attendance, and subjective perceptions of involvement and enjoyment…

  12. The empirical relationship between the managerial conduct and internal control activities in South African small, medium and micro enterprises

    Directory of Open Access Journals (Sweden)

    Juan-Pierre Bruwer

    2017-07-01

    Aim: Since a system of internal control comprises five inter-related elements, while also taking into consideration that management is ultimately responsible for the internal control in their respective business entities, which is greatly influenced by their managerial conduct, this research study placed focus on determining the relationship which exist between the managerial conduct and the internal control activities evident in South African SMMEs. Setting: This study was conducted in the Cape Metropole, South Africa by obtaining responses from 240 stakeholders of SMMEs: 120 members of management and 120 employees. Methods: In order to achieve the latter, quantitative data were collected through a questionnaire and analysed accordingly through both descriptive statistics and inferential statistics. Results: From the results, a very weak negative statistically significant relationship was identified between the managerial conduct and the internal control activities evident in South African SMMEs. Conclusion: Essentially, management and employees should revisit the internal control activities evident in their respective SMMEs through placing emphasis on those internal control activities which can be built on their control environment.

  13. Proceedings of the second international conference on environmental impact assessment of all economical activities. Vol. 1

    International Nuclear Information System (INIS)

    1993-01-01

    Proceedings of the conference consist of 3 volumes: Vol. 1 - 'Environmental Impact Assessment of all Economical Activities including Industry'; Vol. 2 - 'Air Pollution Control and Prevention'; Vol. 3 - Waste Management and Environmental Problems in Construction Industry'. Out of 32 papers contained in Vol. 1, 2 were inputted to INIS. They deal with models of radionuclide transport in food chains and the use of aerial monitoring in the study of environmental contamination. (Z.S.)

  14. International Fusion Materials Irradiation Facility conceptual design activity. Present status and perspective

    International Nuclear Information System (INIS)

    Kondo, Tatsuo; Noda, Kenji; Oyama, Yukio

    1998-01-01

    For developing the materials for nuclear fusion reactors, it is indispensable to study on the neutron irradiation behavior under fusion reactor conditions, but there is not any high energy neutron irradiation facility that can simulate fusion reactor conditions at present. Therefore, the investigation of the IFMIF was begun jointly by Japan, USA, Europe and Russia following the initiative of IEA. The conceptual design activities were completed in 1997. As to the background and the course, the present status of the research on heavy irradiation and the testing means for fusion materials, the requirement and the technical basis of high energy neutron irradiation, and the international joint design activities are reported. The materials for fusion reactors are exposed to the neutron irradiation with the energy spectra up to 14 MeV. The requirements from the users that the IFMIF should satisfy, the demand of the tests for the materials of prototype and demonstration fusion reactors and the evaluation of the neutron field characteristics of the IFMIF are discussed. As to the conceptual design of the IFMIF, the whole constitution, the operational mode, accelerator system and target system are described. (K.I.)

  15. Energy efficiency analyses of active flow aftertreatment systems for lean burn internal combustion engines

    International Nuclear Information System (INIS)

    Zheng Ming; Reader, Graham T.

    2004-01-01

    The use of three way catalytic converters in stoichiometric burn reciprocating internal combustion engine systems has proved to be an effective and efficient method for reducing the level of criteria pollutants. However, such passive systems have not been as successful in emission amelioration when combined with lean burn engines. This is because of the thermochemical nature of the exhaust gases generated by such engines. The high content of exhaust oxygen largely negates the effectiveness of three way catalytic converters, and the comparatively low temperature of the combusted gases means that supplemental energy has to be added to these gases to enable the converter to function correctly. This requirement severely reduces the energy efficiency of conventional passive aftertreatment systems. However, initial empirical studies have indicated that a possible means of improving the performance of aftertreatment devices when used with lean burn engine systems is to use active flow control of the exhaust gases. These results are reported in this paper. This concept has been further investigated by developing an energy efficiency analysis that enables the effects on aftertreatment performance of different gas flow rates, flow reversal frequencies and monolith solid properties to be investigated. Simulation results indicate that through active thermal management, the supplemental energy consumption can be drastically reduced

  16. Protocol for a qualitative study exploring perspectives on the INternational CLassification of Diseases (11th revision); Using lived experience to improve mental health Diagnosis in NHS England: INCLUDE study.

    Science.gov (United States)

    Hackmann, Corinna; Green, Amanda; Notley, Caitlin; Perkins, Amorette; Reed, Geoffrey M; Ridler, Joseph; Wilson, Jon; Shakespeare, Tom

    2017-09-03

    Developed in dialogue with WHO, this research aims to incorporate lived experience and views in the refinement of the International Classification of Diseases Mental and Behavioural Disorders 11th Revision (ICD-11). The validity and clinical utility of psychiatric diagnostic systems has been questioned by both service users and clinicians, as not all aspects reflect their lived experience or are user friendly. This is critical as evidence suggests that diagnosis can impact service user experience, identity, service use and outcomes. Feedback and recommendations from service users and clinicians should help minimise the potential for unintended negative consequences and improve the accuracy, validity and clinical utility of the ICD-11. The name INCLUDE reflects the value of expertise by experience as all aspects of the proposed study are co-produced. Feedback on the planned criteria for the ICD-11 will be sought through focus groups with service users and clinicians. The data from these groups will be coded and inductively analysed using a thematic analysis approach. Findings from this will be used to form the basis of co-produced recommendations for the ICD-11. Two service user focus groups will be conducted for each of these diagnoses: Personality Disorder, Bipolar I Disorder, Schizophrenia, Depressive Disorder and Generalised Anxiety Disorder. There will be four focus groups with clinicians (psychiatrists, general practitioners and clinical psychologists). This study has received ethical approval from the Coventry and Warwickshire HRA Research Ethics Committee (16/WM/0479). The output for the project will be recommendations that reflect the views and experiences of experts by experience (service users and clinicians). The findings will be disseminated via conferences and peer-reviewed publications. As the ICD is an international tool, the aim is for the methodology to be internationally disseminated for replication by other groups. ClinicalTrials.gov: NCT03131505

  17. Kinetics of Hydrogen Radical Reactions with Toluene Including Chemical Activation Theory Employing System-Specific Quantum RRK Theory Calibrated by Variational Transition State Theory.

    Science.gov (United States)

    Bao, Junwei Lucas; Zheng, Jingjing; Truhlar, Donald G

    2016-03-02

    Pressure-dependent reactions are ubiquitous in combustion and atmospheric chemistry. We employ a new calibration procedure for quantum Rice-Ramsperger-Kassel (QRRK) unimolecular rate theory within a chemical activation mechanism to calculate the pressure-falloff effect of a radical association with an aromatic ring. The new theoretical framework is applied to the reaction of H with toluene, which is a prototypical reaction in the combustion chemistry of aromatic hydrocarbons present in most fuels. Both the hydrogen abstraction reactions and the hydrogen addition reactions are calculated. Our system-specific (SS) QRRK approach is adjusted with SS parameters to agree with multistructural canonical variational transition state theory with multidimensional tunneling (MS-CVT/SCT) at the high-pressure limit. The new method avoids the need for the usual empirical estimations of the QRRK parameters, and it eliminates the need for variational transition state theory calculations as a function of energy, although in this first application we do validate the falloff curves by comparing SS-QRRK results without tunneling to multistructural microcanonical variational transition state theory (MS-μVT) rate constants without tunneling. At low temperatures, the two approaches agree well with each other, but at high temperatures, SS-QRRK tends to overestimate falloff slightly. We also show that the variational effect is important in computing the energy-resolved rate constants. Multiple-structure anharmonicity, torsional-potential anharmonicity, and high-frequency-mode vibrational anharmonicity are all included in the rate computations, and torsional anharmonicity effects on the density of states are investigated. Branching fractions, which are both temperature- and pressure-dependent (and for which only limited data is available from experiment), are predicted as a function of pressure.

  18. Dark Skies Ahead? Activities to Raise Awareness during the International Year of Astronomy

    Science.gov (United States)

    Walker, Constance E.; Isbell, D.; Pompea, S.

    2007-12-01

    "Dark Skies as a Universal Resource” is one of 7 themes targeted for the International Year of Astronomy in 2009. The theme's goal is to raise public awareness of the impact of artificial lighting on local environments and the ongoing loss of a dark night sky as a natural resource for much of the world's population. To reach this goal, activities are being developed which highlight dark skies preservation issues 1) through new technology (e.g., programs at planetaria, blogging, podcasting); 2) at events such as star parties and observatory open houses; 3) in arts, entertainment and storytelling (e.g., art competitions, documentaries, lectures, native American traditions); 4) through unaided-eye and digital-meter star count programs involving citizen-scientists; and 5) by relating them to public health, economic issues, ecological consequences, energy conservation, safety and security. A centerpiece of the Dark Skies theme is the unaided-eye and digital-meter versions of the GLOBE at Night program. The unaided-eye version directs citizen-scientists on how to observe and record the brightness of the night sky by matching its appearance toward the constellation of Orion with one of 7 stellar maps of different limiting magnitudes. For the "digital” version, low-cost meters are used by citizen-scientists to measure the integrated sky brightness. Data sets and maps of both versions are supplied on-line for further capstone activities. In the presentation, we will outline the activities being developed as well as plans for funding, implementation, marketing and the connections to the global cornerstone IYA project, "Dark Skies Awareness".

  19. 78 FR 38957 - Agency Information Collection Activities; Comment Request; Trends in International Mathematics...

    Science.gov (United States)

    2013-06-28

    ...; Comment Request; Trends in International Mathematics and Science Study (TIMSS): 2015 Recruitment and Field... of Collection: Trends in International Mathematics and Science Study (TIMSS): 2015 Recruitment and... Mathematics and Science Study (TIMSS) is an international assessment of fourth and eighth grade students...

  20. Rotation and impurity studies in the presence of MHD activity and internal transport barriers on TCV

    Energy Technology Data Exchange (ETDEWEB)

    Federspiel, L. I.

    2014-07-01

    This thesis focuses on measurements of toroidal rotation and impurity profiles in improved plasma scenarios and in the presence of magneto-hydrodynamic (MHD) activity. Experiments were performed on TCV, the Tokamak a Configuration Variable in Lausanne. In TCV, plasma rotation is measured by the charge exchange recombination spectroscopy diagnostic (CXRS). The CXRS is associated with a low power diagnostic neutral beam injector (DNBI) that provides CX emission from the hot plasma core, without perturbing the plasma with additional torque. The beam is observed transversally by the CXRS diagnostic so that local ion temperature, density and intrinsic velocity measurements are obtained. The three systems composing the present day CXRS2013 diagnostic cover the entire TCV radial midplane with up to 80 measurement locations separated by around 7 mm with a time resolution ranging from 2-30 ms. The main upgrades concerned the installation of new sensitive cameras, the overhaul of the toroidal system, the extended-chord configuration and the automation of the acquisition and analysis processes. These new Cars capabilities permitted the investigation of more complex scenarios featuring low intensity and/or fast events, like the low density electron internal transport barriers (eITBs) and the sawtooth (ST) instability. A comparison between rotation profiles measured over several sawtooth events and across a 'canonical' sawtooth cycle has been undertaken in limited L-mode plasmas. The averaged rotation profiles obtained with the upgraded CXRS diagnostic show that ST restrict the maximum attainable and that the rotation profiles are flattened and almost always display a small co-current contribution. It is this effect that results in the 1/I{sub p} scaling observed in TCV limited L-mode plasmas. The co-current core contribution is related to the ST crash, whilst, during the quiescent ramp of the sawtooth period, a plasma recoil outside the mixing radius is observed. A

  1. Rotation and impurity studies in the presence of MHD activity and internal transport barriers on TCV

    International Nuclear Information System (INIS)

    Federspiel, L. I.

    2014-01-01

    This thesis focuses on measurements of toroidal rotation and impurity profiles in improved plasma scenarios and in the presence of magneto-hydrodynamic (MHD) activity. Experiments were performed on TCV, the Tokamak a Configuration Variable in Lausanne. In TCV, plasma rotation is measured by the charge exchange recombination spectroscopy diagnostic (CXRS). The CXRS is associated with a low power diagnostic neutral beam injector (DNBI) that provides CX emission from the hot plasma core, without perturbing the plasma with additional torque. The beam is observed transversally by the CXRS diagnostic so that local ion temperature, density and intrinsic velocity measurements are obtained. The three systems composing the present day CXRS2013 diagnostic cover the entire TCV radial midplane with up to 80 measurement locations separated by around 7 mm with a time resolution ranging from 2-30 ms. The main upgrades concerned the installation of new sensitive cameras, the overhaul of the toroidal system, the extended-chord configuration and the automation of the acquisition and analysis processes. These new Cars capabilities permitted the investigation of more complex scenarios featuring low intensity and/or fast events, like the low density electron internal transport barriers (eITBs) and the sawtooth (ST) instability. A comparison between rotation profiles measured over several sawtooth events and across a 'canonical' sawtooth cycle has been undertaken in limited L-mode plasmas. The averaged rotation profiles obtained with the upgraded CXRS diagnostic show that ST restrict the maximum attainable and that the rotation profiles are flattened and almost always display a small co-current contribution. It is this effect that results in the 1/I p scaling observed in TCV limited L-mode plasmas. The co-current core contribution is related to the ST crash, whilst, during the quiescent ramp of the sawtooth period, a plasma recoil outside the mixing radius is observed. A high

  2. Establishing bounding internal dose estimates for thorium activities at Rocky Flats.

    Science.gov (United States)

    Ulsh, Brant A; Rich, Bryce L; Chew, Melton H; Morris, Robert L; Sharfi, Mutty; Rolfes, Mark R

    2008-07-01

    As part of an evaluation of a Special Exposure Cohort petition filed on behalf of workers at the Rocky Flats Plant, the National Institute for Occupational Safety and Health (NIOSH) was required to demonstrate that bounding values could be established for radiation doses due to the potential intake of all radionuclides present at the facility. The main radioactive elements of interest at Rocky Flats were plutonium and uranium, but much smaller quantities of several other elements, including thorium, were occasionally handled at the site. Bounding potential doses from thorium has proven challenging at other sites due to the early historical difficulty in detecting this element through urinalysis methods and the relatively high internal dose delivered per unit intake. This paper reports the results of NIOSH's investigation of the uses of thorium at Rocky Flats and provides bounding dose reconstructions for these operations. During this investigation, NIOSH reviewed unclassified reports, unclassified extracts of classified materials, material balance and inventory ledgers, monthly progress reports from various groups, and health physics field logbooks, and conducted interviews with former Rocky Flats workers. Thorium operations included: (1) an experimental metal forming project with 240 kg of thorium in 1960; (2) the use of pre-formed parts in weapons mockups; (3) the removal of Th from U; (4) numerous analytical procedures involving trace quantities of thorium; and (5) the possible experimental use of thorium as a mold coating compound. The thorium handling operations at Rocky Flats were limited in scope, well-monitored and documented, and potential doses can be bounded.

  3. Source-book of International Activities Related to the Development of Safety Cases for Deep Geological Repositories

    International Nuclear Information System (INIS)

    2017-01-01

    All national radioactive waste management authorities recognise today that a robust safety case is essential in developing disposal facilities for radioactive waste. To improve the robustness of the safety case for the development of a deep geological repository, a wide variety of activities have been carried out by national programs and international organisations over the past years. The Nuclear Energy Agency, since first introducing the modern concept of the 'safety case', has continued to monitor major developments in safety case activities at the international level. This Source-book summarises the activities being undertaken by the Nuclear Energy Agency, the European Commission and the International Atomic Energy Agency concerning the safety case for the operational and post-closure phases of geological repositories for radioactive waste that ranges from low-level to high-level waste and for spent fuel. In doing so, it highlights important differences in focus among the three organisations

  4. VALIDATION OF THE CHILD AND ADOLESCENT INTERNATIONAL PHYSICAL ACTIVITY QUESTIONNAIRES IN IRANIAN CHILDREN AND ADOLESCENTS

    Directory of Open Access Journals (Sweden)

    Zahra Faghihimani

    2010-11-01

    Full Text Available Abstract    BACKGROUND: With reference to the importance of physical activity during childhood and adolescence in their health promotion and prevention of chronic diseases during adulthood, it is necessary to have a reliable and valid method for evaluating physical activity level in this age group. Physical activity questionnaire child (PAQ-C and adolescents (PAQ-A have been designed for this purpose. This study aimed to validate these questionnaires in a representative sample of Iranian children and adolescents.    METHODS: After translating the PAQ-C and PAQ-A to Persian, the face and content validities of these questionnaires were assessed by a committee of experts of different specialties including specialists in pediatrics, community medicine, social specialist and sport medicine. After minor modification of some items of the questionnaires according to the available types of physical activity and the socio-cultural conditions, the final questionnaires were prepared. Thereafter, 82 children and adolescents with 8 to 18 years of age completed the questionnaires.    RESULTS: To assess the questionnaire reliability Iranian students and the validity accreditation was modified and got from the committee. A Cronbach’s alpha of 0.894 was produced at the end of the analysis showing it has been reliable for this population.    CONCLUSION: According to the results found in this survey, PAQ questionnaire can be used as a reliable and valid method for next studies; so health planning based on Iranian students’ physical activity will be possible in future.      Keywords: Physical Activity Questionnaire, Reliability, Validity.

  5. International conference on safe decommissioning for nuclear activities: Assuring the safe termination of practices involving radioactive materials. Contributed papers

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-07-01

    Thousands of operations involving the use of radioactive substances will end during the current century. While there is considerable regulatory experience in the 'front end' of the regulatory system for practices, the experience at the back end is more limited as fewer practices have actually been terminated. When a practice is terminated because the facility has reached the end of its useful life, action has to betaken to ensure the safe shutdown of the facility and allow the removal of regulatory controls. There are many issues involved in the safe termination of practices. These include setting criteria for the release of material and sites from regulatory control; determining the suitability of the various options for decommissioning nuclear facilities, managing the waste and material released from control (recycling, reuse or disposal), and the eventual remediation of the site. Some countries have put in place regulatory infrastructures and have developed programmes to manage the associated decommissioning and remediation activities. Other countries are at the stage of assessing what is involved in terminating such practices. The purpose of this Conference is to foster an information exchange on the safe an orderly termination of practices that involve the use of radioactive substances, including both decommissioning and environmental remediation, and to promote improved coherence internationally on strategies and criteria for the safe termination of practices.

  6. International conference on safe decommissioning for nuclear activities: Assuring the safe termination of practices involving radioactive materials. Contributed papers

    International Nuclear Information System (INIS)

    2002-01-01

    Thousands of operations involving the use of radioactive substances will end during the current century. While there is considerable regulatory experience in the 'front end' of the regulatory system for practices, the experience at the back end is more limited as fewer practices have actually been terminated. When a practice is terminated because the facility has reached the end of its useful life, action has to betaken to ensure the safe shutdown of the facility and allow the removal of regulatory controls. There are many issues involved in the safe termination of practices. These include setting criteria for the release of material and sites from regulatory control; determining the suitability of the various options for decommissioning nuclear facilities, managing the waste and material released from control (recycling, reuse or disposal), and the eventual remediation of the site. Some countries have put in place regulatory infrastructures and have developed programmes to manage the associated decommissioning and remediation activities. Other countries are at the stage of assessing what is involved in terminating such practices. The purpose of this Conference is to foster an information exchange on the safe an orderly termination of practices that involve the use of radioactive substances, including both decommissioning and environmental remediation, and to promote improved coherence internationally on strategies and criteria for the safe termination of practices

  7. Effects of lifestyle interventions that include a physical activity component in class II and III obese individuals: a systematic review and meta-analysis.

    Directory of Open Access Journals (Sweden)

    Aurélie Baillot

    Full Text Available In class II and III obese individuals, lifestyle intervention is the first step to achieve weight loss and treat obesity-related comorbidities before considering bariatric surgery. A systematic review, meta-analysis, and meta-regression were performed to assess the impact of lifestyle interventions incorporating a physical activity (PA component on health outcomes of class II and III obese individuals.An electronic search was conducted in 4 databases (Medline, Scopus, CINAHL and Sportdiscus. Two independent investigators selected original studies assessing the impact of lifestyle interventions with PA components on anthropometric parameters, cardiometabolic risk factors (fat mass, blood pressure, lipid and glucose metabolism, behaviour modification (PA and nutritional changes, and quality of life in adults with body mass index (BMI ≥ 35 kg/m2. Estimates were pooled using a random-effect model (DerSimonian and Laird method. Heterogeneity between studies was assessed by the Cochran's chi-square test and quantified through an estimation of the I².Of the 3,170 identified articles, 56 met our eligibility criteria, with a large majority of uncontrolled studies (80%. The meta-analysis based on uncontrolled studies showed significant heterogeneity among all included studies. The pooled mean difference in weight loss was 8.9 kg (95% CI, 10.2-7.7; p < 0.01 and 2.8 kg/m² in BMI loss (95% CI, 3.4-2.2; p < 0.01. Long-term interventions produced superior weight loss (11.3 kg compared to short-term (7.2 kg and intermediate-term (8.0 kg interventions. A significant global effect of lifestyle intervention on fat mass, waist circumference, blood pressure, total cholesterol, LDL-C, triglycerides and fasting insulin was found (p<0.01, without significant effect on HDL-C and fasting blood glucose.Lifestyle interventions incorporating a PA component can improve weight and various cardiometabolic risk factors in class II and III obese individuals. However, further

  8. Long-term post-stroke changes include myelin loss, specific deficits in sensory and motor behaviors and complex cognitive impairment detected using active place avoidance.

    Directory of Open Access Journals (Sweden)

    Jin Zhou

    Full Text Available Persistent neurobehavioral deficits and brain changes need validation for brain restoration. Two hours middle cerebral artery occlusion (tMCAO or sham surgery was performed in male Sprague-Dawley rats. Neurobehavioral and cognitive deficits were measured over 10 weeks included: (1 sensory, motor, beam balance, reflex/abnormal responses, hindlimb placement, forepaw foot fault and cylinder placement tests, and (2 complex active place avoidance learning (APA and simple passive avoidance retention (PA. Electroretinogram (ERG, hemispheric loss (infarction, hippocampus CA1 neuronal loss and myelin (Luxol Fast Blue staining in several fiber tracts were also measured. In comparison to Sham surgery, tMCAO surgery produced significant deficits in all behavioral tests except reflex/abnormal responses. Acute, short lived deficits following tMCAO were observed for forelimb foot fault and forelimb cylinder placement. Persistent, sustained deficits for the whole 10 weeks were exhibited for motor (p<0.001, sensory (p<0.001, beam balance performance (p<0.01 and hindlimb placement behavior (p<0.01. tMCAO produced much greater and prolonged cognitive deficits in APA learning (maximum on last trial of 604±83% change, p<0.05 but only a small, comparative effect on PA retention. Hemispheric loss/atrophy was measured 10 weeks after tMCAO and cross-validated by two methods (e.g., almost identical % ischemic hemispheric loss of 33.4±3.5% for H&E and of 34.2±3.5% for TTC staining. No visual dysfunction by ERG and no hippocampus neuronal loss were detected after tMCAO. Fiber tract damage measured by Luxol Fast Blue myelin staining intensity was significant (p<0.01 in the external capsule and striatum but not in corpus callosum and anterior commissure. In summary, persistent neurobehavioral deficits were validated as important endpoints for stroke restorative research in the future. Fiber myelin loss appears to contribute to these long term behavioral dysfunctions and

  9. Mesenchymal Stromal Cell-Derived Microvesicles Regulate an Internal Pro-Inflammatory Program in Activated Macrophages

    Directory of Open Access Journals (Sweden)

    Juan S. Henao Agudelo

    2017-07-01

    Full Text Available Mesenchymal stromal cells (MSCs are multipotent cells with abilities to exert immunosuppressive response promoting tissue repair. Studies have shown that MSCs can secrete extracellular vesicles (MVs-MSCs with similar regulatory functions to the parental cells. Furthermore, strong evidence suggesting that MVs-MSCs can modulate several immune cells (i.e., Th1, Th17, and Foxp3+ T cells. However, their precise effect on macrophages (Mϕs remains unexplored. We investigated the immunoregulatory effect of MVs-MSCs on activated M1-Mϕs in vitro and in vivo using differentiated bone marrow Mϕs and an acute experimental model of thioglycollate-induced peritonitis, respectively. We observed that MVs-MSCs shared surface molecules with MSCs (CD44, CD105, CD90, CD73 and expressed classical microvesicle markers (Annexin V and CD9. The in vitro treatment with MVs-MSCs exerted a regulatory-like phenotype in M1-Mϕs, which showed higher CD206 level and reduced CCR7 expression. This was associated with decreased levels of inflammatory molecules (IL-1β, IL-6, nitric oxide and increased immunoregulatory markers (IL-10 and Arginase in M1-Mϕs. In addition, we detected that MVs-MSCs promoted the downregulation of inflammatory miRNAs (miR-155 and miR-21, as well as, upregulated its predicted target gene SOCS3 in activated M1-Mϕs. In vivo MVs-MSCs treatment reduced the Mϕs infiltrate in the peritoneal cavity inducing a M2-like regulatory phenotype in peritoneal Mϕs (higher arginase activity and reduced expression of CD86, iNOS, IFN-γ, IL-1β, TNF-α, IL-1α, and IL-6 molecules. This in vivo immunomodulatory effect of MVs-MSCs on M1-Mϕs was partially associated with the upregulation of CX3CR1 in F4/80+/Ly6C+/CCR2+ Mϕs subsets. In summary, our findings indicate that MVs-MSCs can modulate an internal program in activated Mϕs establishing an alternative regulatory-like phenotype.

  10. Effectiveness of interventions on physical activity in overweight or obese children: a systematic review and meta-analysis including studies with objectively measured outcomes.

    Science.gov (United States)

    Nooijen, C F J; Galanti, M R; Engström, K; Möller, J; Forsell, Y

    2017-02-01

    There is no consensus on interventions to be recommended in order to promote physical activity among overweight or obese children. The objective of this review was to assess the effects on objectively measured physical activity, of interventions promoting physical activity among overweight or obese children or adolescents, compared to no intervention or to interventions without a physical activity component. Publications up to December 2015 were located through electronic searches for randomized controlled trials resulting in inclusion of 33 studies. Standardized mean differences from baseline to post-intervention and to long-term follow-up were determined for intervention and control groups and meta-analysed using random effects models. The meta-analysis showed that interventions had no effect on total physical activity of overweight and obese children, neither directly post-intervention (-0.02 [-0.15, 0.11]) nor at long-term follow-up (0.07 [-0.27, 0.40]). Separate analyses by typology of intervention (with or without physical fitness, behavioural or environmental components) showed similar results (no effect). In conclusion, there is no evidence that currently available interventions are able to increase physical activity among overweight or obese children. This questions the contribution of physical activity to the treatment of overweight and obesity in children in the studied interventions and calls for other treatment strategies. © 2017 World Obesity Federation.

  11. Validity and reliability of International Physical Activity Questionnaire-Short Form in Chinese youth.

    Science.gov (United States)

    Wang, Chao; Chen, Peijie; Zhuang, Jie

    2013-12-01

    The psychometric profiles of the widely used International Physical Activity Questionnaire-Short Form (IPAQ-SF) in Chinese youth have not been reported. The purpose of this study was to examine the validity and reliability of the IPAQ-SF using a sample of Chinese youth. One thousand and twenty-one youth (M(age) = 14.26 +/- 1.63 years, 52.8% boys) from 11 cities in China wore accelerometers for 7 consecutive days and completed the IPAQ-SF on the 8th day to recall their physical activity (PA) during accelerometer-wearing days. A subsample of 92 youth (M(age) = 15.90 +/- 1.35 years, 46.7% boys) completed the IPAQ-SF again a week later to recall their PA during accelerometer-wearing days. Differences in PA estimated by the IPAQ-SF and accelerometer were examined by paired-sample t test. Spearman correlation coefficients were used to examine the correlation between the IPAQ-SF and accelerometer. Test-retest reliability of the IPAQ-SF was determined by the intraclass correlation coefficient (ICC). Compared with accelerometer, the IPAQ-SF overestimated sedentary time, moderate PA (MPA), vigorous PA (VPA), and moderate-to-vigorous PA (MVPA). Correlations between PA (total PA, MPA, VPA, and MVPA) and sedentary time measured by 2 instruments ranged from "none" to "low" (p = .08-.31). Test-retest ICC of the IPAQ-SF ranged from "moderate" to "high" (ICC = .43-.83), except for sitting in boys (ICC = .06), sitting for the whole sample (ICC = .32), and VPA in girls (ICC = .35). The IPAQ-SF was not a valid instrument for measuring PA and sedentary behavior in Chinese youth.

  12. Pharmacokinetics of digoxin cross-reacting substances in patients with acute yellow oleander (Thevetia peruviana) poisoning, including the effect of activated charcoal.

    Science.gov (United States)

    Roberts, Darren M; Southcott, Emma; Potter, Julia M; Roberts, Michael S; Eddleston, Michael; Buckley, Nick A

    2008-01-01

    Intentional self-poisonings with seeds from the yellow oleander tree (Thevetia peruviana) are widely reported. Activated charcoal has been suggested to benefit patients with yellow oleander poisoning by reducing absorption and/or facilitating elimination. Two recent randomised controlled trials (RCTs) assessing the efficacy of activated charcoal reported conflicting outcomes in terms of mortality. The effect of activated charcoal on the pharmacokinetics of Thevetia cardenolides has not been assessed. This information may be useful for determining whether further studies are necessary. Serial blood samples were obtained from patients enrolled in a RCT assessing the relative efficacy of single dose (SDAC) and multiple doses (MDAC) of activated charcoal compared to no activated charcoal (NoAC). The concentration of Thevetia cardenolides was estimated using a digoxin immunoassay. The effect of activated charcoal on cardenolide pharmacokinetics was compared between treatment groups using the AUC24, the 24h Mean Residence Time (MRT24), and regression lines obtained from serial concentration points adjusted for exposure. Erratic and prolonged absorption patterns were noted in each patient group. The apparent terminal half-life was highly variable, with a median time of 42.9h. There was a reduction in MRT24 and the apparent terminal half-life estimated from linear regression in patients administered activated charcoal compared to the control group (NoAC). This effect was approximately equal in patients administered MDAC or SDAC. Activated charcoal appears to favourably influence the pharmacokinetic profile of Thevetia cardenolides in patients with acute self-poisoning, which may have clinical benefits. Given the conflicting clinical outcomes noted in previous RCTs, this mechanistic data supports the need for further studies to determine whether a subgroup of patients (eg. those presenting soon after poisoning) will benefit from activated charcoal. PMID:17164695

  13. Update of the BIPM comparison BIPM.RI(2)-K1.Cr-51 to include new activity measurements for the LNE-LNHB (France) and the pilot study result of the LNMRI (Brazil)

    Energy Technology Data Exchange (ETDEWEB)

    Ratel, G.; Michotte, C.; Kryeziu, D. [Bureau International des Poids et Mesures (BIPM), 92 - Sevres (France); Moune, M. [CEA Saclay, Laboratoire National de Metrologie et d' Essais, Laboratoire National Henri Becquerel (LNE-LNHB), 91 - Gif-sur-Yvette (France); Iwahara, A. [Laboratorio Nacional de Metrologia das Radiacoes Ionizantes (LNMRI), Rio de Janeiro (Brazil)

    2009-04-15

    In 2006, two national metrology institutes (NMI) submitted samples of known activity of {sup 51}Cr solution to the International Reference System (SIR) for activity comparison at the Bureau International des Poids et Mesures (BIPM). Consequently, 28 samples have been submitted since 1977, from nine NMI and three other laboratories. The activities ranged from about 3 MBq to 90 MBq. The key comparison reference value (KCRV) has been updated and the degrees of equivalence between each equivalent activity measured in the SIR and the KCRV have been calculated. The results are given in the form of a matrix for eight laboratories to which the APMP.RI(II)-K2.Cr-51 results have been added. A graphical presentation is also given. (authors)

  14. IFMIF, International Fusion Materials Irradiation Facility conceptual design activity cost report

    International Nuclear Information System (INIS)

    Rennich, M.J.

    1996-12-01

    This report documents the cost estimate for the International Fusion Materials Irradiation Facility (IFMIF) at the completion of the Conceptual Design Activity (CDA). The estimate corresponds to the design documented in the Final IFMIF CDA Report. In order to effectively involve all the collaborating parties in the development of the estimate, a preparatory meeting was held at Oak Ridge National Laboratory in March 1996 to jointly establish guidelines to insure that the estimate was uniformly prepared while still permitting each country to use customary costing techniques. These guidelines are described in Section 4. A preliminary cost estimate was issued in July 1996 based on the results of the Second Design Integration Meeting, May 20--27, 1996 at JAERI, Tokai, Japan. This document served as the basis for the final costing and review efforts culminating in a final review during the Third IFMIF Design Integration Meeting, October 14--25, 1996, ENEA, Frascati, Italy. The present estimate is a baseline cost estimate which does not apply to a specific site. A revised cost estimate will be prepared following the assignment of both the site and all the facility responsibilities

  15. International intercomparison of fluence of fast neutrons using 115In(n,γ) activation

    International Nuclear Information System (INIS)

    Lesiecki, H.; Cosack, M.

    1985-07-01

    The Physikalisch-Technische Bundesanstalt (PTB) has participated in an international intercomparison of fluence measurements of fast neutrons. This was organized under the auspices of the ''Comite Consultatif pour les Etalons de Mesure des Rayonnements Ionisants (CCEMRI)'', Sect. 3 (Mesures Neutronique). The National Physical Laboratory (NPL), Teddington, UK volunteered to assume responsibility for the experimental realization and final evaluation. This report deals with the measurements performed at the PTB for the neutron fluence intercomparison at neutron energies of Esub(n) = 144 keV and 570 keV which was based on the 115 In(n,γ) 116 Insup(m) reaction. The count rate of a 4πβ-counter which had to be used to determine the activation of the In sample was to be compared with the neutron fluence by which the sample was irradiated. A description of the neutron production, the fluence determination, the 4πβ-counting, and the evaluation of the results will be given. (orig.) [de

  16. Proceedings of the second international conference on environmental impact assessment of all economical activities. Vol. 3

    International Nuclear Information System (INIS)

    1993-01-01

    Proceedings of the conference consist of 3 volumes: Vol. 1 - 'Environmental Impact Assessment of all Economical Activities including Industry'; Vol. 2 - 'Air Pollution Control and Prevention'; Vol. 3 - Waste Management and Environmental Problems in Construction Industry'. Out of 39 papers contained in Vol. 3, 3 were inputted to INIS. They deal with the use of portable radioisotope X-ray fluorescence analyzers in the determination of building material contamination by toxic elements, with underground waste repositories and ground water contamination, and the impact of the Temelin nuclear power plant on the hydrosphere and other environmental components. (Z.S.)

  17. Validation of the German version of the patient activation measure 13 (PAM13-D in an international multicentre study of primary care patients.

    Directory of Open Access Journals (Sweden)

    Katja Brenk-Franz

    Full Text Available The patients' active participation in their medical care is important for patients with chronic diseases. Measurements of patient activation are needed for studies and in clinical practice. This study aims to validate the Patient Activation Measure 13 (PAM13-D in German-speaking primary care patients. This international cross-sectional multicentre study enrolled consecutively patients from primary care practices in three German-speaking countries: Germany, Austria, and Switzerland. Patients completed the PAM13-D questionnaire. General Self-Efficacy scale (GSE was used to assess convergent validity. Furthermore Cronbach's alpha was performed to assess internal consistency. Exploratory factor analysis was used to evaluate the underlying factor structure of the items. We included 508 patients from 16 primary care practices in the final analysis. Results were internally consistent, with a Cronbach's alpha of 0.84. Factor analysis revealed one major underlying factor. The mean values of the PAM13-D correlated significantly (r = 0.43 with those of the GSE. The German PAM13 is a reliable and valid measure of patient activation. Thus, it may be useful in primary care clinical practice and research.

  18. Self-reported activity in tortured refugees with long-term sequelae including pain and the impact of foot pain from falanga - a cross-sectional study

    DEFF Research Database (Denmark)

    Prip, Karen; Persson, Ann L; Sjölund, Bengt H

    2011-01-01

    , among them pain and mobility problems. All had been subjected to various forms of physical and psychological torture and 71 victims had also suffered falanga. Main outcome measures used were: the Disability Rating Index (DRI; 12 items) to assess self-reported capacity to carry out daily activities......; for falanga victims, a specific foot assessment of sensory function in the feet. Results. All patients perceived clear activity limitations according to the DRI. The falanga victims' feet were categorised according to the type of foot pain: stimulus-independent pain; stimulus-evoked pain; no pain. The two...... of victims who had chronic pain for at least 5 years after torture, all perceived activity limitations, but pain from falanga had a greater overall impact on disability assessed in terms of daily activities....

  19. Personal Hearing Protection including Active Noise Reduction (Les dispositifs de protection de l'ouie, y compris l'attenuation du bruit actif) (CD-ROM)

    National Research Council Canada - National Science Library

    Steeneken, H. J; Dancer, A; McKinley, R; Buck, K; James, S

    2005-01-01

    .... SYSTEMS DETAIL NOTE: Adobe Acrobat Reader is included on disc. ABSTRACT: Personal hearing protection and speech communication facilities are essential for optimal performance in military operations...

  20. XF-70 and XF-73, novel antibacterial agents active against slow-growing and non-dividing cultures of Staphylococcus aureus including biofilms.

    Science.gov (United States)

    Ooi, Nicola; Miller, Keith; Randall, Christopher; Rhys-Williams, William; Love, William; Chopra, Ian

    2010-01-01

    Slow-growing and non-dividing bacteria exhibit tolerance to many antibiotics. However, membrane-active agents may act against bacteria in all growth phases. We sought to examine whether the novel porphyrin antibacterial agents XF-70 and XF-73, which have rapid membrane-perturbing activity against Staphylococcus aureus, retained antistaphylococcal activity against growth-attenuated cells. The killing kinetics of XF-70, XF-73 and various comparator agents against exponential phase cultures of S. aureus SH1000 were compared with effects on cells held at 4 degrees C, non-growing cultures expressing the stringent response induced by mupirocin and bacteria in the stationary phase. Biofilms of S. aureus SH1000 were generated with the Calgary device to examine the activities of XF-70 and XF-73 under a further system exhibiting diminished bacterial growth. Cold culture, stringent response and stationary phase cultures remained susceptible to XF-70 and XF-73, which caused > or =5 log reductions in viability over 2 h. During this period the most active comparator agents (chlorhexidine and cetyltrimethylammonium bromide) only promoted a 3 log drop in viability. XF-70 and XF-73 were also highly active against biofilms, with both agents exhibiting low biofilm MICs (1 mg/L) and minimum biofilm eradication concentrations (2 mg/L). XF-70 and XF-73 remained highly active against various forms of slow-growing or non-dividing S. aureus. The results support the hypothesis that membrane-active agents may be particularly effective in eradicating slow- or non-growing bacteria and suggest that XF-70 and XF-73 could be utilized to treat staphylococcal infections where the organisms are only dividing slowly, such as biofilm-associated infections of prosthetic devices.

  1. The IAEA International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO): Status, Ongoing Activities and Outlook

    International Nuclear Information System (INIS)

    Kupitz, Juergen; Depisch, Frank; Azpitarte, Osvaldo

    2004-01-01

    The IAEA General Conference (2000) invited 'all interested Member States to combine their efforts under the aegis of the IAEA in considering the issues of the nuclear fuel cycle, in particular by examining innovative and proliferation-resistant nuclear technology'. In response to this invitation, the IAEA initiated the International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO). The overall objectives of INPRO are to help to ensure that nuclear energy is available to contribute in fulfilling energy needs in the 21. century in a sustainable manner, and to bring together both technology holders and technology users to consider jointly the international and national actions required to achieve desired innovations in nuclear reactors and fuel cycles. In order to fulfil these objectives, the first phase of INPRO dealt with the development of a methodology to assess and compare the performance of innovative nuclear energy systems. This methodology includes the definition of a set of Basic principles, User requirements and Criteria to be met in different areas (Economics, Sustainability and environment, Safety of nuclear installations, Waste management and Proliferation resistance). The result of this phase was presented in a IAEA document (IAEA-TECDOC-1362, Guidance for the evaluation of innovative nuclear reactors and fuel cycles) issued in June 2003. In the present phase of the project, case studies are being carried out in order to validate and improve the developed methodology and the defined set of Basic principles, User requirements and Criteria. This paper shortly summarizes the results published in IAEA-TECDOC-1362 and the ongoing actions related to case studies. Finally, an outlook of INPRO activities is presented. (authors)

  2. Acid phosphatase activity in the liver of Indian desert gerbil (Meriones hurrianae, Jerdon) exposed to internal β-irradiation

    International Nuclear Information System (INIS)

    Gupta, N.K.; Kumar, A.; Sharma, S.

    1985-01-01

    Alterations in acid phosphatase activity in the liver of Indian desert gerbil after administration of 45 Ca are reported. There is an increase in the enzyme activity during early periods after 45 Ca administration. The response of the enzyme to internal irradiation was dose dependent. The enzyme activity remained elevated for a longer period in animals given the higher dose. With starting repair, the activity declined and control values were nearly obtained on the 28 posttreatment day in gerbils having received 37 kBq/g body weight of 45 Ca. Animals with higher doses could not survive till this period

  3. Influences of general self-efficacy and weight bias internalization on physical activity in bariatric surgery candidates.

    Science.gov (United States)

    Hübner, Claudia; Baldofski, Sabrina; Zenger, Markus; Tigges, Wolfgang; Herbig, Beate; Jurowich, Christian; Kaiser, Stefan; Dietrich, Arne; Hilbert, Anja

    2015-01-01

    Physical activity (PA) seems to be important for long-term weight loss after bariatric surgery; however, studies provide evidence for insufficient PA levels in bariatric patients. Research found self-efficacy to be associated with PA and weight bias internalization, for which an influence on mental and physical health has been shown in recent studies. The purpose of the present study was to investigate the influence of general self-efficacy on PA, mediated by weight bias internalization. In 179 bariatric surgery candidates, general self-efficacy, weight bias internalization, and different intensities of PA were assessed by self-report questionnaires. Structural equation modeling was used to analyze the assumed mediational relationship. After controlling for sociodemographic variables, weight bias internalization fully mediated the association between general self-efficacy and moderate-intense as well as vigorous-intense PA. Lower general self-efficacy predicted greater weight bias internalization, which in turn predicted lower levels of moderate-intense and vigorous-intense PA. The results suggest an influence of weight bias internalization on preoperative PA in bariatric surgery candidates. Subsequently, implementation of interventions addressing weight bias internalization in the usual treatment of bariatric surgery candidates might enhance patients' preoperative PA, while longitudinal analyses are needed to further examine its predictive value on PA after bariatric surgery. Copyright © 2015 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.

  4. IFMIF (International Fusion Materials Irradiation Facility) conceptual design activity reduced cost report

    International Nuclear Information System (INIS)

    2000-02-01

    This report describes the results of a preliminary reevaluation of the design and cost of the International Fusion Materials Irradiation Facility (IFMIF) Project in response to the request from the 28th FPCC meeting in January 1999. Two major ideas have been considered: 1) reduction of the total construction cost through elimination of the previously planned facility upgrade and 2) a facility deployment in 3 stages with capabilities for limited experiments in the first stage. As a result, the size and complexity of the facility could be significantly reduced, leading to substantial cost savings. In addition to these two ideas, this study also included a critical review of the original CDA specification with the objective of elimination of nonessential items. For example, the number of lithium targets was reduced from two to one. As a result of these changes in addition to the elimination of the upgrade, the total cost estimate was very substantially reduced from 797.2 MICF to 487.8 MICF, where 1 MICF = 1 Million of the IFMIF Conversion Units (approximately $1M US January, 1996). (author)

  5. Activator Gcn4 Employs Multiple Segments of Med15/Gal11, Including the KIX Domain, to Recruit Mediator to Target Genes in Vivo*♦

    OpenAIRE

    Jedidi, Iness; Zhang, Fan; Qiu, Hongfang; Stahl, Stephen J.; Palmer, Ira; Kaufman, Joshua D.; Nadaud, Philippe S.; Mukherjee, Sujoy; Wingfield, Paul T.; Jaroniec, Christopher P.; Hinnebusch, Alan G.

    2009-01-01

    Mediator is a multisubunit coactivator required for initiation by RNA polymerase II. The Mediator tail subdomain, containing Med15/Gal11, is a target of the activator Gcn4 in vivo, critical for recruitment of native Mediator or the Mediator tail subdomain present in sin4Δ cells. Although several Gal11 segments were previously shown to bind Gcn4 in vitro, the importance of these interactions for recruitment of Mediator and transcriptional activation by Gcn4 in cells was unknown. We show that i...

  6. Activities of the Sociedad Española de Astronomia during the International Year of Astronomy 2009

    Science.gov (United States)

    Montesinos, B.

    2011-11-01

    In this paper we summarize the activities carried out by the SpanishAstronomical Society during the International Year of Astronomy2009. The Society contributed with several key projects to the overallpool of actions coordinated from the National Node, trying -andachieving- to reach as many people as possible through thepublication and free distribution of the book "Astronomia madein Spain" and a collaboration with the digital edition of El Paisduring the entire year 2009. Other activities and by-products are alsodescribed.

  7. Canada and international financial institutions

    OpenAIRE

    Robert Lafrance; James Powell

    1996-01-01

    International financial institutions, such as the International Monetary Fund, the World Bank and the Bank for International Settlements, are important players in the global financial system. This article provides an overview of the major international financial institutions to which Canada belongs. The paper highlights their activities and the nature of Canada's involvement, including that of the Bank of Canada. Recent initiatives coming out of the Halifax and Lyon Summits to improve the eff...

  8. Phosphoproteome and transcription factor activity profiling identify actions of the anti-inflammatory agent UTL-5g in LPS stimulated RAW 264.7 cells including disrupting actin remodeling and STAT-3 activation.

    Science.gov (United States)

    Carruthers, Nicholas J; Stemmer, Paul M; Chen, Ben; Valeriote, Frederick; Gao, Xiaohua; Guatam, Subhash C; Shaw, Jiajiu

    2017-09-15

    UTL-5g is a novel small-molecule TNF-alpha modulator. It reduces cisplatin-induced side effects by protecting kidney, liver, and platelets, thereby increasing tolerance for cisplatin. UTL-5g also reduces radiation-induced acute liver toxicity. The mechanism of action for UTL-5g is not clear at the present time. A phosphoproteomic analysis to a depth of 4943 phosphopeptides and a luminescence-based transcription factor activity assay were used to provide complementary analyses of signaling events that were disrupted by UTL-5g in RAW 264.7 cells. Transcriptional activity downstream of the interferon gamma, IL-6, type 1 Interferon, TGF-β, PKC/Ca 2+ and the glucocorticoid receptor pathways were disrupted by UTL-5g. Phosphoproteomic analysis indicated that hyperphosphorylation of proteins involved in actin remodeling was suppressed by UTL-5g (gene set analysis, FDR 5g. This global characterization of UTL-5g activity in a macrophage cell line discovered that it disrupts selected aspects of LPS signaling including Stat3 activation and actin remodeling providing new insight on how UTL-5g acts to reduce cisplatin-induced side effects. Copyright © 2017 Elsevier B.V. All rights reserved.

  9. A Rooster and a Bean Seed. Active Learning Lessons. Economics International.

    Science.gov (United States)

    Lelyuk, Julia

    This lesson plan was developed through "Economics International," an international program to help build economic education infrastructures in the emerging market economies. It provides a description of the lesson; appropriate age level; economic concepts; content standards and benchmarks; related subject areas; instructional objectives;…

  10. A Lesson about the Circular Flow. Active Learning Lessons. Economics International.

    Science.gov (United States)

    Landfried, Janet

    This lesson plan was developed through "Economics International," an international program to help build economic education infrastructures in the emerging market economies. It provides a lesson description; appropriate grade level; economic concepts; content standards and benchmarks; related subjects; instructional objectives; time…

  11. The Economic Impact of UUM International Students' Expenditure on Business Activities in Changlun

    Science.gov (United States)

    Hassan, Sallahuddin; Othman, Zalila; Sabudin, Noor Sa'adah; Mohaideen, Zalina Mohd; Hidthir, Mohamad Helmi

    2018-01-01

    This study examines the potential impact from the expenditure patterns of UUM international students in Changlun on local development particularly among Changlun businesses. For this purpose, the international students' expenditure patterns in Changlun are examined in terms of the estimated monthly expenditure, the location of spending and the…

  12. Effectiveness of Group Activity Play Therapy on Internalizing and Externalizing Behavior Problems of Preadolescent Orphans in Uganda

    Science.gov (United States)

    Ojiambo, Deborah

    2011-01-01

    This pilot study investigated the impact of group activity play therapy (GAPT) on displaced orphans aged 10 to 12 years living in a large children's village in Uganda. Teachers and housemothers identified 60 preadolescents exhibiting clinical levels of internalizing and externalizing behavior problems. The participants' ethnicity was African and…

  13. Internal standard method for determination of gallium and some trace elements in bauxite by neutron activation analysis

    International Nuclear Information System (INIS)

    Chen, S.G.; Tsai, H.T.

    1983-01-01

    A method is described for the determination of gallium and other trace elements such as Ce, Cr, Hf, Lu and Th in bauxite by the technique of neutron activation analysis using gold as internal standard. Isopropyl ether was used as organic extractant radioactive gallium from the sample. This method yields very good accuracy with a relative error of +-3%. (author)

  14. Sustainability in a global context: How does local factor affect the outcomes of CSR activities in international business units?

    DEFF Research Database (Denmark)

    Thomsen, Christa; Lauring, Jakob

    In recent years CSR has become increasingly important for the activities and branding of MNCs. While some studies have investigated CSR management and branding in domestic situations, fewer studies exist in the case of international business units (subsidiaries, joint ventures, and franchises...

  15. Development of operational models of receptor activation including constitutive receptor activity and their use to determine the efficacy of the chemokine CCL17 at the CC chemokine receptor CCR4.

    Science.gov (United States)

    Slack, R J; Hall, D A

    2012-07-01

    BACKGROUND AND PURPOSE The operational model provides a key conceptual framework for the analysis of pharmacological data. However, this model does not include constitutive receptor activity, a frequent phenomenon in modern pharmacology, particularly in recombinant systems. Here, we developed extensions of the operational model which include constitutive activity and applied them to effects of agonists at the chemokine receptor CCR4. EXPERIMENTAL APPROACH The effects of agonists of CCR4 on [(35) S]GTPγS binding to recombinant cell membranes and on the filamentous (F-) actin content of human CD4(+) CCR4(+) T cells were determined. The basal [(35) S]GTPγS binding was changed by varying the GDP concentration whilst the basal F-actin contents of the higher expressing T cell populations were elevated, suggesting constitutive activity of CCR4. Both sets of data were analysed using the mathematical models. RESULTS The affinity of CCL17 (also known as TARC) derived from analysis of the T cell data (pK(a) = 9.61 ± 0.17) was consistent with radioligand binding experiments (9.50 ± 0.11) while that from the [(35) S]GTPγS binding experiments was lower (8.27 ± 0.09). Its intrinsic efficacy differed between the two systems (110 in T cells vs. 11). CONCLUSIONS AND IMPLICATIONS The presence of constitutive receptor activity allows the absolute intrinsic efficacy of agonists to be determined without a contribution from the signal transduction system. Intrinsic efficacy estimated in this way is consistent with Furchgott's definition of this property. CCL17 may have a higher intrinsic efficacy at CCR4 in human T cells than that expressed recombinantly in CHO cells. © 2012 GSK Services Unlimited. British Journal of Pharmacology © 2012 The British Pharmacological Society.

  16. INDICATORS THAT CAN BE USED TO MEASURE PERFORMANCE IN THE INTERNAL AUDITING ACTIVITIES

    Directory of Open Access Journals (Sweden)

    Florin BOGHEAN

    2016-07-01

    Full Text Available Internal auditing has evolved from an approach based essentially on accounting aspects to a profession oriented towards management of entities and essentially destined for them. Modern internal auditing provides services that incorporate the examination and appreciation of regulations, performances, risk management and governance of all kind of property types – public or private bodies. The financial aspects represent just a part of the internal auditing view. In this paper, we will try to submit a series of indicators that can be used to measure the added value generated in an entity. Internal auditors provide to managers the information they need in order to download their responsibilities. Internal auditors are vitally involved in aspects that address to the risks and governance of the organization.

  17. B-Raf and CRHR1 internalization mediate biphasic ERK1/2 activation by CRH in hippocampal HT22 Cells.

    Science.gov (United States)

    Bonfiglio, Juan J; Inda, Carolina; Senin, Sergio; Maccarrone, Giuseppina; Refojo, Damián; Giacomini, Damiana; Turck, Christoph W; Holsboer, Florian; Arzt, Eduardo; Silberstein, Susana

    2013-03-01

    CRH is a key regulator of neuroendocrine, autonomic, and behavioral response to stress. CRH-stimulated CRH receptor 1 (CRHR1) activates ERK1/2 depending on intracellular context. In a previous work, we demonstrated that CRH activates ERK1/2 in limbic areas of the mouse brain (hippocampus and basolateral amygdala). ERK1/2 is an essential mediator of hippocampal physiological processes including emotional behavior, synaptic plasticity, learning, and memory. To elucidate the molecular mechanisms by which CRH activates ERK1/2 in hippocampal neurons, we used the mouse hippocampal cell line HT22. We document for the first time that ERK1/2 activation in response to CRH is biphasic, involving a first cAMP- and B-Raf-dependent early phase and a second phase that critically depends on CRHR1 internalization and β-arrestin2. By means of mass-spectrometry-based screening, we identified B-Raf-associated proteins that coimmunoprecipitate with endogenous B-Raf after CRHR1 activation. Using molecular and pharmacological tools, the functional impact of selected B-Raf partners in CRH-dependent ERK1/2 activation was dissected. These results indicate that 14-3-3 proteins, protein kinase A, and Rap1, are essential for early CRH-induced ERK1/2 activation, whereas dynamin and vimentin are required for the CRHR1 internalization-dependent phase. Both phases of ERK1/2 activation depend on calcium influx and are affected by calcium/calmodulin-dependent protein kinase II inactivation. Thus, this report describes the dynamics and biphasic nature of ERK1/2 activation downstream neuronal CRHR1 and identifies several new critical components of the CRHR1 signaling machinery that selectively controls the early and late phases of ERK1/2 activation, thus providing new potential therapeutic targets for stress-related disorders.

  18. Update of the ongoing comparison BIPM.RI(II)-K1.Se-75 to include recent activity measurements of the radionuclide {sup 75}Se by the LNE-LNHB (France)

    Energy Technology Data Exchange (ETDEWEB)

    Michotte, C.; Courte, S.; Ratel, G. [Bureau International des Poids et Mesures (BIPM), Pavillon de Breteuil, F-92312 Sevres cedex (France); Moune, M.; Bobin, C. [Laboratoire national de metrologie et d' essais-Laboratoire National Henri Becquerel (LNE-LNHB), Gif-sur-Yvette Cedex (France)

    2011-06-15

    In 2006, to update their previous result of 1992, the LNE-LNHB submitted a new sample of {sup 75}Se with an activity of about 2.2 MBq to the International Reference System (SIR) for activity comparison at the Bureau International des Poids et Mesures (BIPM). This comparison has the identifier BIPM.RI(II)-K1.Se-75. The degree of equivalence between the equivalent activity measured in the SIR for the new LNE-LNHB sample and the updated key comparison reference value (KCRV) has been calculated, as have the degrees of equivalence with each of the other participants. The results are given in the form of a matrix and a graphical presentation is also given. (authors)

  19. TU-G-BRD-06: The Imaging and Radiation Oncology Core Houston (IROC Houston) QA Center International Activities Outside North America

    Energy Technology Data Exchange (ETDEWEB)

    Followill, D; Kry, S; Molineu, A; Lowenstein, J; Alvarez, P; Taylor, P; Nguyen, H; Hernandez, N; Lujano, C; Nguyen, T; Keith, T; Roll, J; Tailor, A [UT MD Anderson Cancer Center, Houston, TX (United States)

    2015-06-15

    Purpose: To describe the extent of IROC Houston’s (formerly the RPC) QA activities and audit results for radiotherapy institutions outside of North America (NA). Methods: The IROC Houston’s QA program components were designed to audit the radiation dose calculation chain from the NIST traceable reference beam calibration, to inclusion of dosimetry parameters used to calculate tumor doses, to the delivery of the radiation dose. The QA program provided to international institutions includes: 1) remote TLD/OSLD audit of machine output, 2) credentialing for advanced technologies, and 3) review of patient treatment records. IROC Houston uses the same standards and acceptance criteria for all of its audits whether for North American or international sites. Results: IROC Houston’s QA program has reached out to radiotherapy sites in 43 different countries since 2013 through their participation in clinical trials. In the past two years, 2,778 international megavoltage beam outputs were audited with OSLD/TLD. While the average IROC/Inst ratio is near unity for all sites monitored, there are international regions whose results are significantly different from the NA region. In the past 2 years, 477 and 87 IMRT H&N phantoms were irradiated at NA and international sites, respectively. Regardless of the OSLD beam audit results, the overall pass rate (87 percent) for all international sites (no region separation) is equal to the NA sites. Of the 182 international patient charts reviewed, 10.7 percent of the dose calculation points did not meet our acceptance criterion as compared to 13.6 percent for NA sites. The lower pass rate for NA sites results from a much larger brachytherapy component which has been shown to be more error prone. Conclusion: IROC Houston has expanded its QA services worldwide and continues a long history of improving radiotherapy dose delivery in many countries. Funding received for QA audit services from the Korean GOG, DAHANCA, EORTC, ICON and CMIC

  20. TU-G-BRD-06: The Imaging and Radiation Oncology Core Houston (IROC Houston) QA Center International Activities Outside North America

    International Nuclear Information System (INIS)

    Followill, D; Kry, S; Molineu, A; Lowenstein, J; Alvarez, P; Taylor, P; Nguyen, H; Hernandez, N; Lujano, C; Nguyen, T; Keith, T; Roll, J; Tailor, A

    2015-01-01

    Purpose: To describe the extent of IROC Houston’s (formerly the RPC) QA activities and audit results for radiotherapy institutions outside of North America (NA). Methods: The IROC Houston’s QA program components were designed to audit the radiation dose calculation chain from the NIST traceable reference beam calibration, to inclusion of dosimetry parameters used to calculate tumor doses, to the delivery of the radiation dose. The QA program provided to international institutions includes: 1) remote TLD/OSLD audit of machine output, 2) credentialing for advanced technologies, and 3) review of patient treatment records. IROC Houston uses the same standards and acceptance criteria for all of its audits whether for North American or international sites. Results: IROC Houston’s QA program has reached out to radiotherapy sites in 43 different countries since 2013 through their participation in clinical trials. In the past two years, 2,778 international megavoltage beam outputs were audited with OSLD/TLD. While the average IROC/Inst ratio is near unity for all sites monitored, there are international regions whose results are significantly different from the NA region. In the past 2 years, 477 and 87 IMRT H&N phantoms were irradiated at NA and international sites, respectively. Regardless of the OSLD beam audit results, the overall pass rate (87 percent) for all international sites (no region separation) is equal to the NA sites. Of the 182 international patient charts reviewed, 10.7 percent of the dose calculation points did not meet our acceptance criterion as compared to 13.6 percent for NA sites. The lower pass rate for NA sites results from a much larger brachytherapy component which has been shown to be more error prone. Conclusion: IROC Houston has expanded its QA services worldwide and continues a long history of improving radiotherapy dose delivery in many countries. Funding received for QA audit services from the Korean GOG, DAHANCA, EORTC, ICON and CMIC