Forces and energetics of intermittent swimming

Science.gov (United States)

Floryan, Daniel; Van Buren, Tyler; Smits, Alexander J.

2017-08-01

Experiments are reported on intermittent swimming motions. Water tunnel experiments on a nominally two-dimensional pitching foil show that the mean thrust and power scale linearly with the duty cycle, from a value of 0.2 all the way up to continuous motions, indicating that individual bursts of activity in intermittent motions are independent of each other. This conclusion is corroborated by particle image velocimetry (PIV) flow visualizations, which show that the main vortical structures in the wake do not change with duty cycle. The experimental data also demonstrate that intermittent motions are generally energetically advantageous over continuous motions. When metabolic energy losses are taken into account, this conclusion is maintained for metabolic power fractions less than 1.

Unsteady propulsion by an intermittent swimming gait

Science.gov (United States)

Akoz, Emre; Moored, Keith W.

2018-01-01

Inviscid computational results are presented on a self-propelled swimmer modeled as a virtual body combined with a two-dimensional hydrofoil pitching intermittently about its leading edge. Lighthill (1971) originally proposed that this burst-and-coast behavior can save fish energy during swimming by taking advantage of the viscous Bone-Lighthill boundary layer thinning mechanism. Here, an additional inviscid Garrick mechanism is discovered that allows swimmers to control the ratio of their added mass thrust-producing forces to their circulatory drag-inducing forces by decreasing their duty cycle, DC, of locomotion. This mechanism can save intermittent swimmers as much as 60% of the energy it takes to swim continuously at the same speed. The inviscid energy savings are shown to increase with increasing amplitude of motion, increase with decreasing Lighthill number, Li, and switch to an energetic cost above continuous swimming for sufficiently low DC. Intermittent swimmers are observed to shed four vortices per cycle that form into groups that are self-similar with the DC. In addition, previous thrust and power scaling laws of continuous self-propelled swimming are further generalized to include intermittent swimming. The key is that by averaging the thrust and power coefficients over only the bursting period then the intermittent problem can be transformed into a continuous one. Furthermore, the intermittent thrust and power scaling relations are extended to predict the mean speed and cost of transport of swimmers. By tuning a few coefficients with a handful of simulations these self-propelled relations can become predictive. In the current study, the mean speed and cost of transport are predicted to within 3% and 18% of their full-scale values by using these relations.

Intermittent theta-burst transcranial magnetic stimulation for treatment of Parkinson disease.

Science.gov (United States)

Benninger, D H; Berman, B D; Houdayer, E; Pal, N; Luckenbaugh, D A; Schneider, L; Miranda, S; Hallett, M

2011-02-15

To investigate the safety and efficacy of intermittent theta-burst stimulation (iTBS) in the treatment of motor symptoms in Parkinson disease (PD). Progression of PD is characterized by the emergence of motor deficits, which eventually respond less to dopaminergic therapy and pose a therapeutic challenge. Repetitive transcranial magnetic stimulation (rTMS) has shown promising results in improving gait, a major cause of disability, and may provide a therapeutic alternative. iTBS is a novel type of rTMS that may be more efficacious than conventional rTMS. In this randomized, double-blind, sham-controlled study, we investigated safety and efficacy of iTBS of the motor and dorsolateral prefrontal cortices in 8 sessions over 2 weeks (evidence Class I). Assessment of safety and clinical efficacy over a 1-month period included timed tests of gait and bradykinesia, Unified Parkinson's Disease Rating Scale (UPDRS), and additional clinical, neuropsychological, and neurophysiologic measures. We investigated 26 patients with mild to moderate PD: 13 received iTBS and 13 sham stimulation. We found beneficial effects of iTBS on mood, but no improvement of gait, bradykinesia, UPDRS, and other measures. EEG/EMG monitoring recorded no pathologic increase of cortical excitability or epileptic activity. Few reported discomfort or pain and one experienced tinnitus during real stimulation. iTBS of the motor and prefrontal cortices appears safe and improves mood, but failed to improve motor performance and functional status in PD. This study provides Class I evidence that iTBS was not effective for gait, upper extremity bradykinesia, or other motor symptoms in PD.

Current direction-dependent modulation of human hand motor function by intermittent theta burst stimulation (iTBS).

Science.gov (United States)

Shirota, Yuichiro; Dhaka, Suman; Paulus, Walter; Sommer, Martin

2017-05-22

Transcranial magnetic stimulation (TMS) with different current directions can activate different sets of neurons. Current direction can also affect the results of repetitive TMS. To test the influence of uni-directional intermittent theta burst stimulation (iTBS) using different current directions, namely posteroanterior (PA) and anteroposterior (AP), on motor behaviour. In a cross-over design, PA- and AP-iTBS was applied over the left primary motor cortex in 19 healthy, right-handed volunteers. Performance of a finger-tapping task was recorded before and 0, 10, 20, and 30min after the iTBS. The task was conducted with the right and left hands separately at each time point. As a control, AP-iTBS with reduced intensity was applied to 14 participants in a separate session (AP weak condition). The finger-tapping count with the left hand was decreased after PA-iTBS. Neither AP- nor AP weak -iTBS altered the performance. Current direction had a significant impact on the after-effects of iTBS. Copyright © 2017 Elsevier B.V. All rights reserved.

Intermittent theta-burst transcranial magnetic stimulation for autism spectrum disorder: an open-label pilot study

Directory of Open Access Journals (Sweden)

Caio Abujadi

2017-12-01

Full Text Available Objective: Theta-burst stimulation (TBS modulates synaptic plasticity more efficiently than standard repetitive transcranial magnetic stimulation delivery and may be a promising modality for neuropsychiatric disorders such as autism spectrum disorder (ASD. At present there are few effective interventions for prefrontal cortex dysfunction in ASD. We report on an open-label, pilot study of intermittent TBS (iTBS to target executive function deficits and restricted, repetitive behaviors in male children and adolescents with ASD. Methods: Ten right-handed, male participants, aged 9-17 years with ASD were enrolled in an open-label trial of iTBS treatment. Fifteen sessions of neuronavigated iTBS at 100% motor threshold targeting the right dorsolateral prefrontal cortex were delivered over 3 weeks. Results: Parent report scores on the Repetitive Behavior Scale Revised and the Yale-Brown Obsessive Compulsive Scale demonstrated improvements with iTBS treatment. Participants demonstrated improvements in perseverative errors on the Wisconsin Card Sorting Test and total time for the Stroop test. The iTBS treatments were well tolerated with no serious adverse effects. Conclusion: These preliminary results suggest that further controlled interventional studies of iTBS for ASD are warranted.

Intermittent theta-burst transcranial magnetic stimulation for autism spectrum disorder: an open-label pilot study.

Science.gov (United States)

Abujadi, Caio; Croarkin, Paul E; Bellini, Bianca B; Brentani, Helena; Marcolin, Marco A

2017-12-11

Theta-burst stimulation (TBS) modulates synaptic plasticity more efficiently than standard repetitive transcranial magnetic stimulation delivery and may be a promising modality for neuropsychiatric disorders such as autism spectrum disorder (ASD). At present there are few effective interventions for prefrontal cortex dysfunction in ASD. We report on an open-label, pilot study of intermittent TBS (iTBS) to target executive function deficits and restricted, repetitive behaviors in male children and adolescents with ASD. Ten right-handed, male participants, aged 9-17 years with ASD were enrolled in an open-label trial of iTBS treatment. Fifteen sessions of neuronavigated iTBS at 100% motor threshold targeting the right dorsolateral prefrontal cortex were delivered over 3 weeks. Parent report scores on the Repetitive Behavior Scale Revised and the Yale-Brown Obsessive Compulsive Scale demonstrated improvements with iTBS treatment. Participants demonstrated improvements in perseverative errors on the Wisconsin Card Sorting Test and total time for the Stroop test. The iTBS treatments were well tolerated with no serious adverse effects. These preliminary results suggest that further controlled interventional studies of iTBS for ASD are warranted.

Distributed Position-Based Consensus of Second-Order Multiagent Systems With Continuous/Intermittent Communication.

Science.gov (United States)

Song, Qiang; Liu, Fang; Wen, Guanghui; Cao, Jinde; Yang, Xinsong

2017-04-24

This paper considers the position-based consensus in a network of agents with double-integrator dynamics and directed topology. Two types of distributed observer algorithms are proposed to solve the consensus problem by utilizing continuous and intermittent position measurements, respectively, where each observer does not interact with any other observers. For the case of continuous communication between network agents, some convergence conditions are derived for reaching consensus in the network with a single constant delay or multiple time-varying delays on the basis of the eigenvalue analysis and the descriptor method. When the network agents can only obtain intermittent position data from local neighbors at discrete time instants, the consensus in the network without time delay or with nonuniform delays is investigated by using the Wirtinger's inequality and the delayed-input approach. Numerical examples are given to illustrate the theoretical analysis.

Inspiratory time and tidal volume during intermittent positive pressure ventilation.

OpenAIRE

Field, D; Milner, A D; Hopkin, I E

1985-01-01

We measured the tidal volume achieved during intermittent positive pressure ventilation using various inspiratory times with a minimum of 0.2 seconds. Results indicate that tidal volume shows no reduction with inspiratory times down to 0.4 seconds. An inspiratory time of 0.3 seconds, however, is likely to reduce tidal volume by 8%, and at 0.2 seconds a 22% fall may be anticipated.

The galactic position dependence of fast radio bursts and the discovery of FRB011025

Energy Technology Data Exchange (ETDEWEB)

Burke-Spolaor, Sarah [California Institute of Technology, 1200 E California Blvd, Pasadena, CA (United States); Bannister, Keith W., E-mail: sarahbspolaor@gmail.com [CSIRO Astronomy and Space Sciences, P.O. Box 76, Epping NSW 1710 (Australia)

2014-09-01

We report the detection of a dispersed fast radio burst (FRB) in archival intermediate-latitude Parkes Radio Telescope data. The burst appears to be of the same physical origin as the four purported extragalactic FRBs reported by Thornton et al. This burst's arrival time precedes the Thornton et al. bursts by 10 years. We consider that this survey, and many other archival low-latitude (|gb| < 30°) pulsar surveys, have been searched for FRBs but produced fewer detections than the comparatively brief Thornton et al. search. Such a rate dependence on Galactic position could provide critical supporting evidence for an extragalactic origin for FRBs. To test this, we form an analytic expression to account for Galactic position and survey setup in FRB rate predictions. Employing a sky temperature, scattering, and dispersion model of the Milky Way, we compute the expected number of FRBs if they are isotropically distributed on the sky with respect to the Galactic position (i.e., local), and if they are of extragalactic origin. We demonstrate that the relative detection rates reject a local origin with a confidence of 99.96% (∼3.6σ). The extragalactic predictions provide a better agreement; however, there are still strong discrepancies with the low-latitude detection rate at a confidence of 99.69% (∼2.9σ). However, for the extragalactic population, the differences in predicted versus detected population may be accounted for by a number of factors, which we discuss.

The galactic position dependence of fast radio bursts and the discovery of FRB011025

International Nuclear Information System (INIS)

Burke-Spolaor, Sarah; Bannister, Keith W.

2014-01-01

We report the detection of a dispersed fast radio burst (FRB) in archival intermediate-latitude Parkes Radio Telescope data. The burst appears to be of the same physical origin as the four purported extragalactic FRBs reported by Thornton et al. This burst's arrival time precedes the Thornton et al. bursts by 10 years. We consider that this survey, and many other archival low-latitude (|gb| < 30°) pulsar surveys, have been searched for FRBs but produced fewer detections than the comparatively brief Thornton et al. search. Such a rate dependence on Galactic position could provide critical supporting evidence for an extragalactic origin for FRBs. To test this, we form an analytic expression to account for Galactic position and survey setup in FRB rate predictions. Employing a sky temperature, scattering, and dispersion model of the Milky Way, we compute the expected number of FRBs if they are isotropically distributed on the sky with respect to the Galactic position (i.e., local), and if they are of extragalactic origin. We demonstrate that the relative detection rates reject a local origin with a confidence of 99.96% (∼3.6σ). The extragalactic predictions provide a better agreement; however, there are still strong discrepancies with the low-latitude detection rate at a confidence of 99.69% (∼2.9σ). However, for the extragalactic population, the differences in predicted versus detected population may be accounted for by a number of factors, which we discuss.

Plasticity Induced by Intermittent Theta Burst Stimulation in Bilateral Motor Cortices Is Not Altered in Older Adults

Directory of Open Access Journals (Sweden)

Daina S. E. Dickins

2015-01-01

Full Text Available Numerous studies have reported that plasticity induced in the motor cortex by transcranial magnetic stimulation (TMS is attenuated in older adults. Those investigations, however, have focused solely on the stimulated hemisphere. Compared to young adults, older adults exhibit more widespread activity across bilateral motor cortices during the performance of unilateral motor tasks, suggesting that the manifestation of plasticity might also be altered. To address this question, twenty young (65 years underwent intermittent theta burst stimulation (iTBS whilst attending to the hand targeted by the plasticity-inducing procedure. The amplitude of motor evoked potentials (MEPs elicited by single pulse TMS was used to quantify cortical excitability before and after iTBS. Individual responses to iTBS were highly variable, with half the participants showing an unexpected decrease in cortical excitability. Contrary to predictions, however, there were no age-related differences in the magnitude or manifestation of plasticity across bilateral motor cortices. The findings suggest that advancing age does not influence the capacity for, or manifestation of, plasticity induced by iTBS.

Plasticity Induced by Intermittent Theta Burst Stimulation in Bilateral Motor Cortices Is Not Altered in Older Adults

Science.gov (United States)

Dickins, Daina S. E.; Sale, Martin V.

2015-01-01

Numerous studies have reported that plasticity induced in the motor cortex by transcranial magnetic stimulation (TMS) is attenuated in older adults. Those investigations, however, have focused solely on the stimulated hemisphere. Compared to young adults, older adults exhibit more widespread activity across bilateral motor cortices during the performance of unilateral motor tasks, suggesting that the manifestation of plasticity might also be altered. To address this question, twenty young (65 years) underwent intermittent theta burst stimulation (iTBS) whilst attending to the hand targeted by the plasticity-inducing procedure. The amplitude of motor evoked potentials (MEPs) elicited by single pulse TMS was used to quantify cortical excitability before and after iTBS. Individual responses to iTBS were highly variable, with half the participants showing an unexpected decrease in cortical excitability. Contrary to predictions, however, there were no age-related differences in the magnitude or manifestation of plasticity across bilateral motor cortices. The findings suggest that advancing age does not influence the capacity for, or manifestation of, plasticity induced by iTBS. PMID:26064691

Burst-suppression is reactive to photic stimulation in comatose children with acquired brain injury

DEFF Research Database (Denmark)

Nita, Dragos A.; Moldovan, Mihai; Sharma, Roy

2016-01-01

reactivity. We quantified reactivity by measuring the change in the burst ratio (fraction of time in burst) following photic stimulation. Results: Photic stimulation evoked bursts in all patients, resulting in a transient increase in the burst ratio, while the mean heart rate remained unchanged......Objective: Burst-suppression is an electroencephalographic pattern observed during coma. In individuals without known brain pathologies undergoing deep general anesthesia, somatosensory stimulation transiently increases the occurrence of bursts. We investigated the reactivity of burst......-suppression in children with acquired brain injury. Methods: Intensive care unit electroencephalographic monitoring recordings containing burst-suppression were obtained from 5 comatose children with acquired brain injury of various etiologies. Intermittent photic stimulation was performed at 1 Hz for 1 min to assess...

Inter- and Intra-individual variability following intermittent theta burst stimulation: implications for rehabilitation and recovery.

Science.gov (United States)

Hinder, Mark R; Goss, Emily L; Fujiyama, Hakuei; Canty, Alison J; Garry, Michael I; Rodger, Jennifer; Summers, Jeffery J

2014-01-01

The continued refinement of non-invasive brain stimulation (NBS) techniques is indicative of promising clinical and rehabilitative interventions that are able to modulate cortical excitability. Intermittent theta burst stimulation (iTBS) is one such technique that can increase cortical excitability, purportedly via LTP-like mechanisms. While iTBS may have the capacity to promote recovery after neurological injury, and to combat cognitive and motor decline, recent reports observed highly variable effects across individuals, questioning the efficacy of iTBS as a clinical tool. The aim of this study was to examine intra-individual reliability and inter-individual variability in responses to iTBS. Thirty healthy participants completed two experimental sessions of the iTBS protocol 1-3 weeks apart. Motor evoked potentials in response to single pulse TMS were used to assess corticospinal excitability prior to, and up to 36 min following, iTBS. At the group level, iTBS evoked statistically significant increases in motor cortical excitability across both sessions (P iTBS is capable of inducing relatively robust and consistent effects within and between young individuals. As such, the capacity for iTBS to be exploited in clinical and rehabilitative interventions should continue to be explored. Copyright © 2014 Elsevier Inc. All rights reserved.

Emergent synchronous bursting of oxytocin neuronal network.

Directory of Open Access Journals (Sweden)

Enrico Rossoni

2008-07-01

Full Text Available When young suckle, they are rewarded intermittently with a let-down of milk that results from reflex secretion of the hormone oxytocin; without oxytocin, newly born young will die unless they are fostered. Oxytocin is made by magnocellular hypothalamic neurons, and is secreted from their nerve endings in the pituitary in response to action potentials (spikes that are generated in the cell bodies and which are propagated down their axons to the nerve endings. Normally, oxytocin cells discharge asynchronously at 1-3 spikes/s, but during suckling, every 5 min or so, each discharges a brief, intense burst of spikes that release a pulse of oxytocin into the circulation. This reflex was the first, and is perhaps the best, example of a physiological role for peptide-mediated communication within the brain: it is coordinated by the release of oxytocin from the dendrites of oxytocin cells; it can be facilitated by injection of tiny amounts of oxytocin into the hypothalamus, and it can be blocked by injection of tiny amounts of oxytocin antagonist. Here we show how synchronized bursting can arise in a neuronal network model that incorporates basic observations of the physiology of oxytocin cells. In our model, bursting is an emergent behaviour of a complex system, involving both positive and negative feedbacks, between many sparsely connected cells. The oxytocin cells are regulated by independent afferent inputs, but they interact by local release of oxytocin and endocannabinoids. Oxytocin released from the dendrites of these cells has a positive-feedback effect, while endocannabinoids have an inhibitory effect by suppressing the afferent input to the cells.

Bifurcation structure of a model of bursting pancreatic cells

DEFF Research Database (Denmark)

Mosekilde, Erik; Lading, B.; Yanchuk, S.

2001-01-01

. The transition from this structure to the so-called period-adding structure is found to involve a subcritical period-doubling bifurcation and the emergence of type-III intermittency. The period-adding transition itself is not smooth but consists of a saddle-node bifurcation in which (n + 1)-spike bursting...... behavior is born, slightly overlapping with a subcritical period-doubling bifurcation in which n-spike bursting behavior loses its stability.......One- and two-dimensional bifurcation studies of a prototypic model of bursting oscillations in pancreatic P-cells reveal a squid-formed area of chaotic dynamics in the parameter plane, with period-doubling bifurcations on one side of the arms and saddle-node bifurcations on the other...

Intermittent θ burst stimulation over primary motor cortex enhances movement-related β synchronisation.

Science.gov (United States)

Hsu, Ya-Fang; Liao, Kwong-Kum; Lee, Po-Lei; Tsai, Yun-An; Yeh, Chia-Lung; Lai, Kuan-Lin; Huang, Ying-Zu; Lin, Yung-Yang; Lee, I-Hui

2011-11-01

The objective of this study is to investigate how transcranial magnetic intermittent theta burst stimulation (iTBS) with a prolonged protocol affects human cortical excitability and movement-related oscillations. Using motor-evoked potentials (MEPs) and movement-related magnetoencephalography (MEG), we assessed the changes of corticospinal excitability and cortical oscillations after iTBS with double the conventional stimulation time (1200 pulses, iTBS1200) over the primary motor cortex (M1) in 10 healthy subjects. Continuous TBS (cTBS1200) and sham stimulation served as controls. iTBS1200 facilitated MEPs evoked from the conditioned M1, while inhibiting MEPs from the contralateral M1 for 30 min. By contrast, cTBS1200 inhibited MEPs from the conditioned M1. Importantly, empirical mode decomposition-based MEG analysis showed that the amplitude of post-movement beta synchronisation (16-26 Hz) was significantly increased by iTBS1200 at the conditioned M1, but was suppressed at the nonconditioned M1. Alpha (8-13 Hz) and low gamma-ranged (35-45 Hz) rhythms were not notably affected. Movement kinetics remained consistent throughout. TBS1200 modulated corticospinal excitability in parallel with the direction of conventional paradigms with modestly prolonged efficacy. Moreover, iTBS1200 increased post-movement beta synchronisation of the stimulated M1, and decreased that of the contralateral M1, probably through interhemispheric interaction. Our results provide insight into the underlying mechanism of TBS and reinforce the connection between movement-related beta synchronisation and corticospinal output. Copyright © 2011 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

Agonist contraction during intermittent theta burst stimulation enhances motor cortical plasticity of the wrist flexors.

Science.gov (United States)

Mirdamadi, J L; Suzuki, L Y; Meehan, S K

2015-03-30

Differences in cortical control across the different muscles of the upper limb may mitigate the efficacy of TMS interventions targeting a specific muscle. The current study sought to determine whether weak concurrent contraction during TMS could enhance the efficacy of intermittent theta burst stimulation (iTBS) in the forearm flexors. Motor evoked potentials (MEP) were elicited from the flexor (FCR) and extensor carpi radialis (ECR) motor cortical hotspots before and after iTBS over the FCR cortical hotspot. During iTBS the FCR was either relaxed (iTBS-Relax) or tonically contracted to 10% of maximum voluntary force (iTBS-Contract). iTBS-Relax failed to produce consistent potentiation of MEPFCR amplitude. Individuals with a relatively lower RMTFCR compared RMTECR demonstrated MEPFCR facilitation post-iTBS-Relax. Individuals with relatively higher RMTFCR demonstrated less facilitation and even suppression of MEPFCR amplitude. iTBS-Contract facilitated MEPFCR amplitude but only for MEPFCR evoked from the ECR hotspot. Interactions between overlapping cortical representations determine the efficacy of iTBS. Tonic contraction increases the efficacy of iTBS by enhancing the volume of the cortical representation. However, metaplastic effects may attenuate the enhancement of MEP gain at the motor cortical hotspot. The use of TMS as an adjunct to physical therapy should account for inter-muscle interactions when targeting muscles of the forearm. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

The facilitatory effects of intermittent theta burst stimulation on corticospinal excitability are enhanced by nicotine.

Science.gov (United States)

Swayne, Orlando B C; Teo, James T H; Greenwood, Richard J; Rothwell, John C

2009-08-01

Intermittent theta burst stimulation (iTBS) is increasingly widely used as a means of facilitating corticospinal excitability in the human primary motor cortex. This form of facilitatory plasticity within the stimulated cortex may occur by induction of long term potentiation (LTP). In animal models, agonists of nicotinic acetylcholine receptors have been shown to modulate or induce LTP; we thus sought to test whether nicotine may modulate the effects of iTBS on corticospinal excitability in humans. A double-blind placebo-controlled cross-over design study was conducted with 10 healthy subjects. iTBS was delivered 60min after subjects took either 4mg nicotine or placebo lozenges, and motor-evoked potentials (MEPs) were then recorded for 40min after the end of stimulation. In the placebo arm, iTBS produced an increase in the amplitudes of MEPs which lasted for 5min. In the nicotine arm, iTBS produced a more pronounced facilitation of MEPs that was still present at 40min. In a control experiment, nicotine alone had no effect on MEP amplitudes when given in the absence of iTBS. These data indicate that the effects of iTBS can be enhanced and prolonged by nicotine. These results are consistent with animal models demonstrating nicotinic modulation of facilitatory plasticity, and will be of interest to investigators seeking to enhance artificially induced changes in cortical excitability.

Different types of bursting calcium oscillations in non-excitable cells

International Nuclear Information System (INIS)

Perc, Matjaz; Marhl, Marko

2003-01-01

In the paper different types of bursting Ca 2+ oscillations are presented. We analyse bursting behaviour in four recent mathematical models for Ca 2+ oscillations in non-excitable cells. Separately, regular, quasi-periodic, and chaotic bursting Ca 2+ oscillations are classified into several subtypes. The classification is based on the dynamics of separated fast and slow subsystems, the so-called fast-slow burster analysis. For regular bursting Ca 2+ oscillations two types of bursting are specified: Point-Point and Point-Cycle bursting. In particular, the slow passage effect, important for the Hopf-Hopf and SubHopf-SubHopf bursting subtypes, is explained by local divergence calculated for the fast subsystem. Quasi-periodic bursting Ca 2+ oscillations can be found in only one of the four studied mathematical models and appear via a homoclinic bifurcation with a homoclinic torus structure. For chaotic bursting Ca 2+ oscillations, we found that bursting patterns resulting from the period doubling root to chaos considerably differ from those appearing via intermittency and have to be treated separately. The analysis and classification of different types of bursting Ca 2+ oscillations provides better insight into mechanisms of complex intra- and intercellular Ca 2+ signalling. This improves our understanding of several important biological phenomena in cellular signalling like complex frequency-amplitude signal encoding and synchronisation of intercellular signal transduction between coupled cells in tissue

Intermittent Theta Burst Stimulation Increases Reward Responsiveness in Individuals with Higher Hedonic Capacity.

Science.gov (United States)

Duprat, Romain; De Raedt, Rudi; Wu, Guo-Rong; Baeken, Chris

2016-01-01

Repetitive transcranial magnetic stimulation over the left dorsolateral prefrontal cortex (DLPFC) has been documented to influence striatal and orbitofrontal dopaminergic activity implicated in reward processing. However, the exact neuropsychological mechanisms of how DLPFC stimulation may affect the reward system and how trait hedonic capacity may interact with the effects remains to be elucidated. In this sham-controlled study in healthy individuals, we investigated the effects of a single session of neuronavigated intermittent theta burst stimulation (iTBS) on reward responsiveness, as well as the influence of trait hedonic capacity. We used a randomized crossover single session iTBS design with an interval of 1 week. We assessed reward responsiveness using a rewarded probabilistic learning task and measured individual trait hedonic capacity (the ability to experience pleasure) with the temporal experience of pleasure scale questionnaire. As expected, the participants developed a response bias toward the most rewarded stimulus (rich stimulus). Reaction time and accuracy for the rich stimulus were respectively shorter and higher as compared to the less rewarded stimulus (lean stimulus). Active or sham stimulation did not seem to influence the outcome. However, when taking into account individual trait hedonic capacity, we found an early significant increase in the response bias only after active iTBS. The higher the individual's trait hedonic capacity, the more the response bias toward the rich stimulus increased after the active stimulation. When taking into account trait hedonic capacity, one active iTBS session over the left DLPFC improved reward responsiveness in healthy male participants with higher hedonic capacity. This suggests that individual differences in hedonic capacity may influence the effects of iTBS on the reward system.

A repeating fast radio burst.

Science.gov (United States)

Spitler, L G; Scholz, P; Hessels, J W T; Bogdanov, S; Brazier, A; Camilo, F; Chatterjee, S; Cordes, J M; Crawford, F; Deneva, J; Ferdman, R D; Freire, P C C; Kaspi, V M; Lazarus, P; Lynch, R; Madsen, E C; McLaughlin, M A; Patel, C; Ransom, S M; Seymour, A; Stairs, I H; Stappers, B W; van Leeuwen, J; Zhu, W W

2016-03-10

Fast radio bursts are millisecond-duration astronomical radio pulses of unknown physical origin that appear to come from extragalactic distances. Previous follow-up observations have failed to find additional bursts at the same dispersion measure (that is, the integrated column density of free electrons between source and telescope) and sky position as the original detections. The apparent non-repeating nature of these bursts has led to the suggestion that they originate in cataclysmic events. Here we report observations of ten additional bursts from the direction of the fast radio burst FRB 121102. These bursts have dispersion measures and sky positions consistent with the original burst. This unambiguously identifies FRB 121102 as repeating and demonstrates that its source survives the energetic events that cause the bursts. Additionally, the bursts from FRB 121102 show a wide range of spectral shapes that appear to be predominantly intrinsic to the source and which vary on timescales of minutes or less. Although there may be multiple physical origins for the population of fast radio bursts, these repeat bursts with high dispersion measure and variable spectra specifically seen from the direction of FRB 121102 support an origin in a young, highly magnetized, extragalactic neutron star.

Efficacy and Time Course of Theta Burst Stimulation in Healthy Humans

NARCIS (Netherlands)

Wischnewski, M.; Schutter, D.J.L.G.

2015-01-01

BACKGROUND: In the past decade research has shown that continuous (cTBS) and intermittent theta burst stimulation (iTBS) alter neuronal excitability levels in the primary motor cortex. OBJECTIVE: Quantitatively review the magnitude and time course on cortical excitability of cTBS and iTBS. METHODS:

The effect of stimulation interval on plasticity following repeated blocks of intermittent theta burst stimulation.

Science.gov (United States)

Tse, Nga Yan; Goldsworthy, Mitchell R; Ridding, Michael C; Coxon, James P; Fitzgerald, Paul B; Fornito, Alex; Rogasch, Nigel C

2018-06-04

This study assessed the effect of interval duration on the direction and magnitude of changes in cortical excitability and inhibition when applying repeated blocks of intermittent theta burst stimulation (iTBS) over motor cortex. 15 participants received three different iTBS conditions on separate days: single iTBS; repeated iTBS with a 5 minute interval (iTBS-5-iTBS); and with a 15 minute interval (iTBS-15-iTBS). Changes in cortical excitability and short-interval cortical inhibition (SICI) were assessed via motor-evoked potentials (MEPs) before and up to 60 mins following stimulation. iTBS-15-iTBS increased MEP amplitude for up to 60 mins post stimulation, whereas iTBS-5-iTBS decreased MEP amplitude. In contrast, MEP amplitude was not altered by single iTBS. Despite the group level findings, only 53% of individuals showed facilitated MEPs following iTBS-15-iTBS, and only 40% inhibited MEPs following iTBS-5-iTBS. Modulation of SICI did not differ between conditions. These results suggest interval duration between spaced iTBS plays an important role in determining the direction of plasticity on excitatory, but not inhibitory circuits in human motor cortex. While repeated iTBS can increase the magnitude of MEP facilitation/inhibition in some individuals compared to single iTBS, the response to repeated iTBS appears variable between individuals in this small sample.

Bifurcation structure of a model of bursting pancreatic cells

DEFF Research Database (Denmark)

Mosekilde, Erik; Lading, B.; Yanchuk, S.

2001-01-01

One- and two-dimensional bifurcation studies of a prototypic model of bursting oscillations in pancreatic P-cells reveal a squid-formed area of chaotic dynamics in the parameter plane, with period-doubling bifurcations on one side of the arms and saddle-node bifurcations on the other. The transit......One- and two-dimensional bifurcation studies of a prototypic model of bursting oscillations in pancreatic P-cells reveal a squid-formed area of chaotic dynamics in the parameter plane, with period-doubling bifurcations on one side of the arms and saddle-node bifurcations on the other....... The transition from this structure to the so-called period-adding structure is found to involve a subcritical period-doubling bifurcation and the emergence of type-III intermittency. The period-adding transition itself is not smooth but consists of a saddle-node bifurcation in which (n + 1)-spike bursting...

Bursting and large-scale intermittency in turbulent convection with differential rotation

DEFF Research Database (Denmark)

Garcia, O.E.; Bian, N.H.

2003-01-01

The tilting mechanism, which generates differential rotation in two-dimensional turbulent convection, is shown to produce relaxation oscillations in the mean flow energy integral and bursts in the global fluctuation level, akin to Lotka-Volterra oscillations. The basic reason for such behavior...

Chaotic bursting in semiconductor lasers

Science.gov (United States)

Ruschel, Stefan; Yanchuk, Serhiy

2017-11-01

We investigate the dynamic mechanisms for low frequency fluctuations in semiconductor lasers subjected to delayed optical feedback, using the Lang-Kobayashi model. This system of delay differential equations displays pronounced envelope dynamics, ranging from erratic, so called low frequency fluctuations to regular pulse packages, if the time scales of fast oscillations and envelope dynamics are well separated. We investigate the parameter regions where low frequency fluctuations occur and compute their Lyapunov spectra. Using the geometric singular perturbation theory, we study this intermittent chaotic behavior and characterize these solutions as bursting slow-fast oscillations.

Circuit implementation and multiform intermittency in a hyper-chaotic model extended from the Lorenz system

International Nuclear Information System (INIS)

Shi-Jian, Cang; Zeng-Qiang, Chen; Wen-Juan, Wu

2009-01-01

This paper presents a non-autonomous hyper-chaotic system, which is formed by adding a periodic driving signal to a four-dimensional chaotic model extended from the Lorenz system. The resulting non-autonomous hyper-chaotic system can display any dynamic behaviour among the periodic orbits, intermittency, chaos and hyper-chaos by controlling the frequency of the periodic signal. The phenomenon has been well demonstrated by numerical simulations, bifurcation analysis and electronic circuit realization. Moreover, the system is concrete evidence for the presence of Pomeau–Manneville Type-I intermittency and crisis-induced intermittency. The emergence of a different type of intermittency is similarly subjected to the frequency of periodic forcing. By statistical analysis, power scaling laws consisting in different intermittency are obtained for the lifetime in the laminar state between burst states

Intermittent Theta-Burst Transcranial Magnetic Stimulation Alters Electrical Properties of Fast-Spiking Neocortical Interneurons in an Age-Dependent Fashion

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Kathrin eHoppenrath

2016-03-01

Full Text Available Modulation of human cortical excitability by repetitive transcranial magnetic stimulation (rTMS appears to be in part related to changed activity of inhibitory systems. Our own studies showed that intermittent theta-burst stimulation (iTBS applied via rTMS to rat cortex primarily affects the parvalbumin-expressing (PV fast-spiking interneurons (FSIs, evident via a strongly reduced PV expression. We further found the iTBS effect on PV to be age-dependent since no reduction in PV could be induced before the perineuronal nets (PNNs of FSIs start to grow around postnatal day 30. To elucidate possible iTBS-induced changes in the electrical properties of FSIs and cortical network activity during cortical critical period, we performed ex vivo – in vitro whole-cell patch clamp recordings from pre-labelled FSIs in the current study. FSIs of verum iTBS-treated rats displayed a higher excitability than sham-treated controls at PD29-38, evident as higher rates of induced action potential firing at low current injections (100-200 pA and a more depolarized resting membrane potential. This effect was absent in younger (PD26-28 and older animals (PD40-62. Slices of verum iTBS-treated rats further showed higher rates of spontaneous EPSCs. Based on these and previous findings we conclude that FSIs are particularly sensitive to theta-burst stimulation during early cortical development, when FSIs show an activity-driven step of maturation which is paralleled by intense growth of the PNNs and subsequent closure of the cortical critical period. Although to be proven further, rTMS may be a possible early intervention to compensate for hypo-activity related mal-development of cortical neuronal circuits.

Extubation success in premature infants with respiratory distress syndrome treated with bi-level nasal continuous positive airway pressure versus nasal intermittent positive pressure ventilation.

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Thomas, Patricia E; LeFlore, Judy

2013-01-01

Infants born prematurely with respiratory distress syndrome are at high risk for complications from mechanical ventilation. Strategies are needed to minimize their days on the ventilator. The purpose of this study was to compare extubation success rates in infants treated with 2 different types of continuous positive airway pressure devices. A retrospective cohort study design was used. Data were retrieved from electronic medical records for patients in a large, metropolitan, level III neonatal intensive care unit. A sample of 194 premature infants with respiratory distress syndrome was selected, 124 of whom were treated with nasal intermittent positive pressure ventilation and 70 with bi-level variable flow nasal continuous positive airway pressure (bi-level nasal continuous positive airway pressure). Infants in both groups had high extubation success rates (79% of nasal intermittent positive pressure ventilation group and 77% of bi-level nasal continuous positive airway pressure group). Although infants in the bi-level nasal continuous positive airway pressure group were extubated sooner, there was no difference in duration of oxygen therapy between the 2 groups. Promoting early extubation and extubation success is a vital strategy to reduce complications of mechanical ventilation that adversely affect premature infants with respiratory distress syndrome.

Accelerated intermittent Theta Burst stimulation for suicide risk in therapy-resistant depressed patients: a randomized, sham-controlled trial.

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Stefanie Desmyter

2016-09-01

Full Text Available Objectives We aimed to examine the effects and safety of accelerated intermittent Theta Burst Stimulation (iTBS on suicide risk in a group of treatment-resistant unipolar depressed patients, using an extensive suicide assessment scale. Methods In 50 therapy-resistant, antidepressant-free depressed patients, an intensive protocol of accelerated iTBS was applied over the left dorsolateral prefrontal cortex in a randomized, sham-controlled cross-over design. Patients received 20 iTBS sessions over 4 days. Suicide risk was assessed using the Beck Scale of Suicide ideation (BSI. Results The iTBS protocol was safe and well-tolerated. We observed a significant decrease of the BSI score over time, unrelated to active or sham stimulation and unrelated to depression-response. No worsening of suicidal ideation was observed. The effects of accelerated iTBS on mood and depression severity are reported in Duprat et al. (2016. The decrease in suicide risk lasted up to one month after baseline, even in depression non-responders. Conclusions This accelerated iTBS protocol was safe. The observed significant decrease in suicide risk was unrelated to active or sham stimulation and unrelated to depression response. Further sham-controlled research in suicidal depressed patients is necessary.(clinicaltrials.gov identifier: NCT01832805

Accelerated Intermittent Theta Burst Stimulation for Suicide Risk in Therapy-Resistant Depressed Patients: A Randomized, Sham-Controlled Trial.

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Desmyter, Stefanie; Duprat, Romain; Baeken, Chris; Van Autreve, Sara; Audenaert, Kurt; van Heeringen, Kees

2016-01-01

Objectives: We aimed to examine the effects and safety of accelerated intermittent Theta Burst Stimulation (iTBS) on suicide risk in a group of treatment-resistant unipolar depressed patients, using an extensive suicide assessment scale. Methods: In 50 therapy-resistant, antidepressant-free depressed patients, an intensive protocol of accelerated iTBS was applied over the left dorsolateral prefrontal cortex (DLPFC) in a randomized, sham-controlled crossover design. Patients received 20 iTBS sessions over 4 days. Suicide risk was assessed using the Beck Scale of Suicide ideation (BSI). Results: The iTBS protocol was safe and well tolerated. We observed a significant decrease of the BSI score over time, unrelated to active or sham stimulation and unrelated to depression-response. No worsening of suicidal ideation was observed. The effects of accelerated iTBS on mood and depression severity are reported in Duprat et al. (2016). The decrease in suicide risk lasted up to 1 month after baseline, even in depression non-responders. Conclusions: This accelerated iTBS protocol was safe. The observed significant decrease in suicide risk was unrelated to active or sham stimulation and unrelated to depression response. Further sham-controlled research in suicidal depressed patients is necessary. (Clinicaltrials.gov identifier: NCT01832805).

Spatio-temporal intermittency on the sandpile

International Nuclear Information System (INIS)

Erzan, A.; Sinha, S.

1990-08-01

The self-organized critical state exhibited by a sandpile model is shown to correspond to motion on an attractor characterized by an invariant distribution of the height variable. The largest Lyapunov exponent is equal to zero. The model nonetheless displays intermittent chaos, with a multifractal distribution of local expansion coefficients in history space. Laminar spatio-temporal regions are interrupted by chaotic bursts caused by avalanches. We introduce the concept of local histories in configuration space and show that their expansion parameters also exhibit a multifractal distribution in time and space. (author). 22 refs, 5 figs

Frontoparietal regions may become hypoactive after intermittent theta burst stimulation over the contralateral homologous cortex in humans.

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He, Xiaofei; Lan, Yue; Xu, Guangqing; Mao, Yurong; Chen, Zhenghong; Huang, Dongfeng; Pei, Zhong

2013-12-01

Brain injury to the dorsal frontoparietal networks, including the posterior parietal cortex (PPC) and dorsolateral prefrontal cortex (DLPFC), commonly cause spatial neglect. However, the interaction of these different regions in spatial attention is unclear. The aim of the present study was to investigate whether hyperexcitable neural networks can cause an abnormal interhemispheric inhibition. The Attention Network Test was used to test subjects following intermittent theta burst stimulation (iTBS) to the left or right frontoparietal networks. During the Attention Network Test task, all subjects tolerated each conditioning iTBS without any obvious iTBS-related side effects. Subjects receiving real-right-PPC iTBS showed significant enhancement in both alerting and orienting efficiency compared with those receiving either sham-right-PPC iTBS or real-left-PPC iTBS. Moreover, subjects exposed to the real-right-DLPFC iTBS exhibited significant improvement in both alerting and executive control efficiency, compared with those exposed to either the sham-right-DLPFC or real-left-DLPFC conditioning. Interestingly, compared with subjects exposed to the sham-left-PPC stimuli, subjects exposed to the real-left-PPC iTBS had a significant deficit in the orienting index. The present study indicates that iTBS over the contralateral homologous cortex may induce the hypoactivity of the right PPC through interhemispheric competition in spatial orienting attention.

Understanding the Generation of Network Bursts by Adaptive Oscillatory Neurons

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Tanguy Fardet

2018-02-01

Full Text Available Experimental and numerical studies have revealed that isolated populations of oscillatory neurons can spontaneously synchronize and generate periodic bursts involving the whole network. Such a behavior has notably been observed for cultured neurons in rodent's cortex or hippocampus. We show here that a sufficient condition for this network bursting is the presence of an excitatory population of oscillatory neurons which displays spike-driven adaptation. We provide an analytic model to analyze network bursts generated by coupled adaptive exponential integrate-and-fire neurons. We show that, for strong synaptic coupling, intrinsically tonic spiking neurons evolve to reach a synchronized intermittent bursting state. The presence of inhibitory neurons or plastic synapses can then modulate this dynamics in many ways but is not necessary for its appearance. Thanks to a simple self-consistent equation, our model gives an intuitive and semi-quantitative tool to understand the bursting behavior. Furthermore, it suggests that after-hyperpolarization currents are sufficient to explain bursting termination. Through a thorough mapping between the theoretical parameters and ion-channel properties, we discuss the biological mechanisms that could be involved and the relevance of the explored parameter-space. Such an insight enables us to propose experimentally-testable predictions regarding how blocking fast, medium or slow after-hyperpolarization channels would affect the firing rate and burst duration, as well as the interburst interval.

Response of Preterm Infants to 2 Noninvasive Ventilatory Support Systems: Nasal CPAP and Nasal Intermittent Positive-Pressure Ventilation.

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Silveira, Carmen Salum Thomé; Leonardi, Kamila Maia; Melo, Ana Paula Carvalho Freire; Zaia, José Eduardo; Brunherotti, Marisa Afonso Andrade

2015-12-01

Noninvasive ventilation (NIV) in preterm infants is currently applied using intermittent positive pressure (2 positive-pressure levels) or in a conventional manner (one pressure level). However, there are no studies in the literature comparing the chances of failure of these NIV methods. The aim of this study was to evaluate the occurrence of failure of 2 noninvasive ventilatory support systems in preterm neonates over a period of 48 h. A randomized, prospective, clinical study was conducted on 80 newborns (gestational age CPAP and 40 infants with nasal intermittent positive-pressure ventilation (NIPPV). The occurrence of apnea, progression of respiratory distress, nose bleeding, and agitation was defined as ventilation failure. The need for intubation and re-intubation after failure was also observed. There were no significant differences in birth characteristics between groups. Ventilatory support failure was observed in 25 (62.5%) newborns treated with nasal CPAP and in 12 (30%) newborns treated with NIPPV, indicating an association between NIV failure and the absence of intermittent positive pressure (odds ratio [OR] 1.22, P CPAP failure. After failure, 25% (OR 0.33) of the newborns receiving nasal CPAP and 12.5% (OR 0.14) receiving NIPPV required invasive mechanical ventilation. Ventilatory support failure was significantly more frequent when nasal CPAP was used. Copyright © 2015 by Daedalus Enterprises.

Fast imaging of intermittent electrospraying of water with positive corona discharge

International Nuclear Information System (INIS)

Pongrác, B; Janda, M; Martišovitš, V; Machala, Z; Kim, H H

2014-01-01

The effect of the electrospraying of water in combination with a positive direct current (dc) streamer corona discharge generated in air was investigated in this paper. We employed high-speed camera visualizations and oscilloscopic discharge current measurements in combination with an intensified charge-coupled device camera for fast time-resolved imaging. The repetitive process of Taylor cone formation and droplet formation from the mass fragments of water during the electrospray was visualized. Depending on the applied voltage, the following intermittent modes of electrospraying typical for water were observed: dripping mode, spindle mode, and oscillating-spindle mode. The observed electrospraying modes were repetitive with a frequency of a few hundreds of Hz, as measured from the fast image sequences. This frequency agreed well with the frequency of the measured streamer current pulses. The presence of filamentary streamer discharges at relatively low voltages probably prevented the establishment of a continuous electrospray in the cone–jet mode. After each streamer, a positive glow corona discharge was established on the water filament tip, and it propagated from the stressed electrode along with the water filament elongation. The results show a reciprocal character of intermittent electrospraying of water, and the presence of corona discharge, where both the electrospray and the discharge affect each other. The generation of a corona discharge from the water cone depended on the repetitive process of the cone formation. Also, the propagation and curvature of the water filament were influenced by the discharge and its resultant space charge. Furthermore, these phenomena were partially influenced by the water conductivity. (paper)

Scaling the Thrust Production and Energetics of Inviscid Intermittent Swimming

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Akoz, Emre; Moored, Keith

2015-11-01

Many fish have adopted an intermittent swimming gait sometimes referred as a burst-and-coast behavior. By using this gait, fish have been estimated at reducing their energetic cost of swimming by about 50%. Lighthill proposed that the skin friction drag of an undulating body can be around 400% greater than a rigidly-held coasting body, which may explain the energetic savings of intermittent swimming. Recent studies have confirmed the increase in skin friction drag over an undulating body, however, the increase is on the order of 20-70%. This more modest gain in skin friction drag is not sufficient to lead to the observed energy savings. Motivated by these observations, we investigate the inviscid mechanisms behind intermittent swimming for parameters typical of biology. We see that there is an energy savings at a fixed swimming speed for intermittent swimming as compared to continuous swimming. Then we consider three questions: What is the nature of the inviscid mechanism that leads to the observed energy savings, how do the forces and energetics of intermittent swimming scale with the swimming parameters, and what are the limitations to the benefit? Supported by the Office of Naval Research under Program Director Dr. Bob Brizzola, MURI grant number N00014-14-1-0533.

Effects of intermittent theta-burst stimulation on practice-related changes in fast finger movements in healthy subjects.

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Agostino, Rocco; Iezzi, Ennio; Dinapoli, Loredana; Suppa, Antonio; Conte, Antonella; Berardelli, Alfredo

2008-08-01

In this paper we investigated the effects of intermittent theta-burst stimulation (iTBS) applied to the primary motor cortex on practice-related changes in motor performance. Seventeen healthy subjects underwent two experimental sessions, one testing real iTBS and the other testing sham iTBS. Before and after both iTBS sessions, the subjects practiced fast right index-finger abductions for a few minutes. As measures of cortical excitability we calculated resting motor threshold and motor-evoked potential amplitude. As measures of practice-related changes we evaluated the mean movement amplitude, peak velocity and peak acceleration values for each block. When subjects practiced the movement task, the three variables measuring practice-related changes improved to a similar extent during real and sham iTBS whereas cortical excitability increased only during real iTBS. In a further group of five healthy subjects we investigated the effect of real and sham iTBS on changes in motor performance after a longer task practice and found no significant changes in motor performance and retention after real and sham iTBS. From our results overall we conclude that in healthy subjects iTBS applied to the primary motor cortex leaves practice-related changes in an index finger abduction task unaffected. We suggest that iTBS delivered over the primary motor cortex is insufficient to alter motor performance because early motor learning probably engages a wide cortical and subcortical network.

Boosting the LTP-like plasticity effect of intermittent theta-burst stimulation using gamma transcranial alternating current stimulation.

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Guerra, Andrea; Suppa, Antonio; Bologna, Matteo; D'Onofrio, Valentina; Bianchini, Edoardo; Brown, Peter; Di Lazzaro, Vincenzo; Berardelli, Alfredo

2018-03-24

Transcranial Alternating Current Stimulation (tACS) consists in delivering electric current to the brain using an oscillatory pattern that may entrain the rhythmic activity of cortical neurons. When delivered at gamma frequency, tACS modulates motor performance and GABA-A-ergic interneuron activity. Since interneuronal discharges play a crucial role in brain plasticity phenomena, here we co-stimulated the primary motor cortex (M1) in healthy subjects by means of tACS during intermittent theta-burst stimulation (iTBS), a transcranial magnetic stimulation paradigm known to induce long-term potentiation (LTP)-like plasticity. We measured and compared motor evoked potentials before and after gamma, beta and sham tACS-iTBS. While we delivered gamma-tACS, we also measured short-interval intracortical inhibition (SICI) to detect any changes in GABA-A-ergic neurotransmission. Gamma, but not beta and sham tACS, significantly boosted and prolonged the iTBS-induced after-effects. Interestingly, the extent of the gamma tACS-iTBS after-effects correlated directly with SICI changes. Overall, our findings point to a link between gamma oscillations, interneuronal GABA-A-ergic activity and LTP-like plasticity in the human M1. Gamma tACS-iTBS co-stimulation might represent a new strategy to enhance and prolong responses to plasticity-inducing protocols, thereby lending itself to future applications in the neurorehabilitation setting. Copyright © 2018 Elsevier Inc. All rights reserved.

Intermittent degradation and schizotypy

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Matthew W. Roché

2015-06-01

Full Text Available Intermittent degradation refers to transient detrimental disruptions in task performance. This phenomenon has been repeatedly observed in the performance data of patients with schizophrenia. Whether intermittent degradation is a feature of the liability for schizophrenia (i.e., schizotypy is an open question. Further, the specificity of intermittent degradation to schizotypy has yet to be investigated. To address these questions, 92 undergraduate participants completed a battery of self-report questionnaires assessing schizotypy and psychological state variables (e.g., anxiety, depression, and their reaction times were recorded as they did so. Intermittent degradation was defined as the number of times a subject’s reaction time for questionnaire items met or exceeded three standard deviations from his or her mean reaction time after controlling for each item’s information processing load. Intermittent degradation scores were correlated with questionnaire scores. Our results indicate that intermittent degradation is associated with total scores on measures of positive and disorganized schizotypy, but unrelated to total scores on measures of negative schizotypy and psychological state variables. Intermittent degradation is interpreted as potentially derivative of schizotypy and a candidate endophenotypic marker worthy of continued research.

Multiple blocks of intermittent and continuous theta-burst stimulation applied via transcranial magnetic stimulation differently affect sensory responses in rat barrel cortex.

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Thimm, Andreas; Funke, Klaus

2015-02-15

Theta-burst stimulation (TBS) applied via transcranial magnetic stimulation is able to modulate human cortical excitability. Here we investigated in a rat model how two different forms of TBS, intermittent (iTBS) and continuous (cTBS), affect sensory responses in rat barrel cortex. We found that iTBS but less cTBS promoted late (>18 ms) sensory response components while not affecting the earliest response (8-18 ms). The effect increased with each of the five iTBS blocks applied. cTBS somewhat reduced the early response component after the first block but had a similar effect as iTBS after four to five blocks. We conclude that iTBS primarly modulates the activity of (inhibitory) cortical interneurons while cTBS may first reduce general neuronal excitability with a single block but reverse to iTBS-like effects with application of several blocks. Cortical sensory processing varies with cortical state and the balance of inhibition to excitation. Repetitive transcranial magnetic stimulation (rTMS) has been shown to modulate human cortical excitability. In a rat model, we recently showed that intermittent theta-burst stimulation (iTBS) applied to the corpus callosum, to activate primarily supragranular cortical pyramidal cells but fewer subcortical neurons, strongly reduced the cortical expression of parvalbumin (PV), indicating reduced activity of fast-spiking interneurons. Here, we used the well-studied rodent barrel cortex system to test how iTBS and continuous TBS (cTBS) modulate sensory responses evoked by either single or double stimuli applied to the principal (PW) and/or adjacent whisker (AW) in urethane-anaesthetized rats. Compared to sham stimulation, iTBS but not cTBS particularly enhanced late (>18 ms) response components of multi-unit spiking and local field potential responses in layer 4 but not the very early response (iTBS diminished the suppression of the second response evoked by paired PW or AW-PW stimulation at 20 ms intervals. The effects

Observation of a Pomeau-Manneville intermittent route to chaos in a nonlinear oscillator

International Nuclear Information System (INIS)

Jeffries, C.; Perez, J.

1982-01-01

For a driven nonlinear semiconductor oscillator which shows a period-doubling pitchfork bifurcation route to chaos, we report an additional route to chaos: the Pomeau-Manneville intermittency route, characterized by a periodic (laminar) phase interrupted by bursts of aperiodic behavior. This occurs near a tangent bifurcation as the system driving parameter is reduced by epsilon from the threshold value for a periodic window. Data are presented for the dependence of the average laminar length on epsilon, and also on additive random noise voltage. The results are in reasonable agreement with the intermittency theory of Hirsch, Huberman, and Scalapino. The distribution P(l) is also reported

Positive effects of intermittent fasting in ischemic stroke.

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Fann, David Yang-Wei; Ng, Gavin Yong Quan; Poh, Luting; Arumugam, Thiruma V

2017-03-01

Intermittent fasting (IF) is a dietary protocol where energy restriction is induced by alternate periods of ad libitum feeding and fasting. Prophylactic intermittent fasting has been shown to extend lifespan and attenuate the progress and severity of age-related diseases such as cardiovascular (e.g. stroke and myocardial infarction), neurodegenerative (e.g. Alzheimer's disease and Parkinson's disease) and cancerous diseases in animal models. Stroke is the second leading cause of death, and lifestyle risk factors such as obesity and physical inactivity have been associated with elevated risks of stroke in humans. Recent studies have shown that prophylactic IF may mitigate tissue damage and neurological deficit following ischemic stroke by a mechanism(s) involving suppression of excitotoxicity, oxidative stress, inflammation and cell death pathways in animal stroke models. This review summarizes data supporting the potential hormesis mechanisms of prophylactic IF in animal models, and with a focus on findings from animal studies of prophylactic IF in stroke in our laboratory. Copyright © 2017 Elsevier Inc. All rights reserved.

Spatiotemporal chaos from bursting dynamics

International Nuclear Information System (INIS)

Berenstein, Igal; De Decker, Yannick

2015-01-01

In this paper, we study the emergence of spatiotemporal chaos from mixed-mode oscillations, by using an extended Oregonator model. We show that bursting dynamics consisting of fast/slow mixed mode oscillations along a single attractor can lead to spatiotemporal chaotic dynamics, although the spatially homogeneous solution is itself non-chaotic. This behavior is observed far from the Hopf bifurcation and takes the form of a spatiotemporal intermittency where the system locally alternates between the fast and the slow phases of the mixed mode oscillations. We expect this form of spatiotemporal chaos to be generic for models in which one or several slow variables are coupled to activator-inhibitor type of oscillators

Turbulence and intermittent transport at the boundary of magnetized plasmas

DEFF Research Database (Denmark)

Garcia, O.E.; Naulin, V.; Nielsen, A.H.

2005-01-01

Numerical fluid simulations of interchange turbulence for geometry and parameters relevant to the boundary region of magnetically confined plasmas are shown to result in intermittent transport qualitatively similar to recent experimental measurements. The two-dimensional simulation domain features...... a forcing region with spatially localized sources of particles and heat outside which losses due to the motion along open magnetic-field lines dominate, corresponding to the edge region and the scrape-off layer, respectively. Turbulent states reveal intermittent eruptions of hot plasma from the edge region...... fluctuation wave forms and transport statistics are also in a good agreement with those derived from the experiments. Associated with the turbulence bursts are relaxation oscillations in the particle and heat confinements as well as in the kinetic energy of the sheared poloidal flows. The formation of blob...

Gamma-ray burst observations: the present situation

International Nuclear Information System (INIS)

Vedrenne, G.

1984-01-01

Recent results in gamma ray burst investigations concerning the spectral variability on a short time scale, precise locations, and the discovery of optical flashes in gamma ray burst positions on archival plates are presented. The implications of optical and X-ray observations of gamma ray burst error boxes are also discussed. 72 references

Reversed Effects of Intermittent Theta Burst Stimulation following Motor Training That Vary as a Function of Training-Induced Changes in Corticospinal Excitability

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Tino Stöckel

2015-01-01

Full Text Available Intermittent theta burst stimulation (iTBS has the potential to enhance corticospinal excitability (CSE and subsequent motor learning. However, the effects of iTBS following motor learning are unknown. The purpose of the present study was to explore the effect of iTBS on CSE and performance following motor learning. Therefore twenty-four healthy participants practiced a ballistic motor task for a total of 150 movements. iTBS was subsequently applied to the trained motor cortex (STIM group or the vertex (SHAM group. Performance and CSE were assessed before motor learning and before and after iTBS. Training significantly increased performance and CSE in both groups. In STIM group participants, subsequent iTBS significantly reduced motor performance with smaller reductions in CSE. CSE changes as a result of motor learning were negatively correlated with both the CSE changes and performance changes as a result of iTBS. No significant effects of iTBS were found for SHAM group participants. We conclude that iTBS has the potential to degrade prior motor learning as a function of training-induced CSE changes. That means the expected LTP-like effects of iTBS are reversed following motor learning.

Reversed Effects of Intermittent Theta Burst Stimulation following Motor Training That Vary as a Function of Training-Induced Changes in Corticospinal Excitability.

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Stöckel, Tino; Summers, Jeffery J; Hinder, Mark R

2015-01-01

Intermittent theta burst stimulation (iTBS) has the potential to enhance corticospinal excitability (CSE) and subsequent motor learning. However, the effects of iTBS following motor learning are unknown. The purpose of the present study was to explore the effect of iTBS on CSE and performance following motor learning. Therefore twenty-four healthy participants practiced a ballistic motor task for a total of 150 movements. iTBS was subsequently applied to the trained motor cortex (STIM group) or the vertex (SHAM group). Performance and CSE were assessed before motor learning and before and after iTBS. Training significantly increased performance and CSE in both groups. In STIM group participants, subsequent iTBS significantly reduced motor performance with smaller reductions in CSE. CSE changes as a result of motor learning were negatively correlated with both the CSE changes and performance changes as a result of iTBS. No significant effects of iTBS were found for SHAM group participants. We conclude that iTBS has the potential to degrade prior motor learning as a function of training-induced CSE changes. That means the expected LTP-like effects of iTBS are reversed following motor learning.

Observations of short gamma-ray bursts.

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Fox, Derek B; Roming, Peter W A

2007-05-15

We review recent observations of short-hard gamma-ray bursts and their afterglows. The launch and successful ongoing operations of the Swift satellite, along with several localizations from the High-Energy Transient Explorer mission, have provoked a revolution in short-burst studies: first, by quickly providing high-quality positions to observers; and second, via rapid and sustained observations from the Swift satellite itself. We make a complete accounting of Swift-era short-burst localizations and proposed host galaxies, and discuss the implications of these observations for the distances, energetics and environments of short bursts, and the nature of their progenitors. We then review the physical modelling of short-burst afterglows: while the simplest afterglow models are inadequate to explain the observations, there have been several notable successes. Finally, we address the case of an unusual burst that threatens to upset the simple picture in which long bursts are due to the deaths of massive stars, and short bursts to compact-object merger events.

Losartan reduces the immediate and sustained increases in muscle sympathetic nerve activity after hyperacute intermittent hypoxia.

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Jouett, Noah P; Moralez, Gilbert; Raven, Peter B; Smith, Michael L

2017-04-01

Obstructive sleep apnea (OSA) is characterized by intermittent hypoxemia, which produces elevations in sympathetic nerve activity (SNA) and associated hypertension in experimental models that persist beyond the initial exposure. We tested the hypotheses that angiotensin receptor blockade in humans using losartan attenuates the immediate and immediately persistent increases in 1 ) SNA discharge and 2 ) mean arterial pressure (MAP) after hyperacute intermittent hypoxia training (IHT) using a randomized, placebo-controlled, repeated-measures experimental design. We measured ECG and photoplethysmographic arterial pressure in nine healthy human subjects, while muscle SNA (MSNA) was recorded in seven subjects using microneurography. Subjects were exposed to a series of hypoxic apneas in which they inhaled two to three breaths of nitrogen, followed by a 20-s apnea and 40 s of room air breathing every minute for 20 min. Hyperacute IHT produced substantial and persistent elevations in MSNA burst frequency (baseline: 15.3 ± 1.8, IHT: 24 ± 1.5, post-IHT 20.0 ± 1.3 bursts/min, all P 0.70). This investigation confirms the role of angiotensin II type 1a receptors in the immediate and persistent sympathoexcitatory and pressor responses to IHT. NEW & NOTEWORTHY This study demonstrates for the first time in humans that losartan, an angiotensin receptor blocker (ARB), abrogates the acute and immediately persistent increases in muscle sympathetic nerve activity and arterial pressure in response to acute intermittent hypoxia. This investigation, along with others, provides important beginning translational evidence for using ARBs in treatment of the intermittent hypoxia observed in obstructive sleep apnea patients. Copyright © 2017 the American Physiological Society.

A 2-center Comparative Study on Tonic Versus Burst Spinal Cord Stimulation: Amount of Responders and Amount of Pain Suppression

NARCIS (Netherlands)

Ridder, D.M.D.; Lenders, M.W.P.M.; de Vos, Cecilia Cecilia Clementine; Dijkstra-Scholten, C.R.N.; Wolters, R.R.N.; Vancamp, T.P.T.; Van Looy, P.R.N.; Van Havenbergh, T.M.D.; Vanneste, S.

2015-01-01

Introduction: Spinal cord stimulation is a safe and effective procedure applied for medically intractable neuropathic pain and failed back surgery syndrome. Recently, a novel stimulation paradigm was developed, called burst stimulation consisting of intermittent packets of closely spaced

Intermittent dislocation density fluctuations in crystal plasticity from a phase-field crystal model

DEFF Research Database (Denmark)

Tarp, Jens M.; Angheluta, Luiza; Mathiesen, Joachim

2014-01-01

Plastic deformation mediated by collective dislocation dynamics is investigated in the two-dimensional phase-field crystal model of sheared single crystals. We find that intermittent fluctuations in the dislocation population number accompany bursts in the plastic strain-rate fluctuations...... propose a simple stochastic model of dislocation reaction kinetics that is able to capture these statistical properties of the dislocation density fluctuations as a function of shear rate....

AUTOMATIC RECOGNITION OF CORONAL TYPE II RADIO BURSTS: THE AUTOMATED RADIO BURST IDENTIFICATION SYSTEM METHOD AND FIRST OBSERVATIONS

International Nuclear Information System (INIS)

Lobzin, Vasili V.; Cairns, Iver H.; Robinson, Peter A.; Steward, Graham; Patterson, Garth

2010-01-01

Major space weather events such as solar flares and coronal mass ejections are usually accompanied by solar radio bursts, which can potentially be used for real-time space weather forecasts. Type II radio bursts are produced near the local plasma frequency and its harmonic by fast electrons accelerated by a shock wave moving through the corona and solar wind with a typical speed of ∼1000 km s -1 . The coronal bursts have dynamic spectra with frequency gradually falling with time and durations of several minutes. This Letter presents a new method developed to detect type II coronal radio bursts automatically and describes its implementation in an extended Automated Radio Burst Identification System (ARBIS 2). Preliminary tests of the method with spectra obtained in 2002 show that the performance of the current implementation is quite high, ∼80%, while the probability of false positives is reasonably low, with one false positive per 100-200 hr for high solar activity and less than one false event per 10000 hr for low solar activity periods. The first automatically detected coronal type II radio burst is also presented.

Modulation of inhibitory activity markers by intermittent theta-burst stimulation in rat cortex is NMDA-receptor dependent.

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Labedi, Adnan; Benali, Alia; Mix, Annika; Neubacher, Ute; Funke, Klaus

2014-01-01

Intermittent theta-burst stimulation (iTBS) applied via transcranial magnetic stimulation has been shown to increase cortical excitability in humans. In the rat brain it strongly reduced the number of neurons expressing the 67-kD isoform of the GABA-synthesizing enzyme glutamic acid decarboxylase (GAD67) and those expressing the calcium-binding proteins parvalbumin (PV) and calbindin (CB), specific markers of fast-spiking (FS) and non-FS inhibitory interneurons, respectively, an indication of modified cortical inhibition. Since iTBS effects in humans have been shown to be NMDA receptor sensitive, we wondered whether the iTBS-induced changes in the molecular phenotype of interneurons may be also sensitive to glutamatergic synaptic transmission mediated by NMDA receptors. In a sham-controlled fashion, five iTBS-blocks of 600 stimuli were applied to rats either lightly anesthetized by only urethane or by an additional low (subnarcotic) or high dose of the NMDA receptor antagonist ketamine before immunohistochemical analysis. iTBS reduced the number of neurons expressing GAD67, PV and CB. Except for CB, a low dose of ketamine partially prevented these effects while a higher dose almost completely abolished the iTBS effects. Our findings indicate that iTBS modulates the molecular, and likely also the electric, activity of cortical inhibitory interneurons and that the modulation of FS-type but less that of non-FS-type neurons is mediated by NMDA receptors. A combination of iTBS with pharmacological interventions affecting distinct receptor subtypes may thus offer options to enhance its selectivity in modulating the activity of distinct cell types and preventing others from being modulated. Copyright © 2014 Elsevier Inc. All rights reserved.

The effect of single and repeated prefrontal intermittent theta burst stimulation on cortical reactivity and working memory.

Science.gov (United States)

Chung, Sung Wook; Rogasch, Nigel C; Hoy, Kate E; Fitzgerald, Paul B

With an increasing interest in the use of theta burst stimulation (TBS) as a cognitive enhancer and a potential therapeutic tool for psychiatric disorders, there is a need to identify optimal parameters of TBS in the prefrontal cortex. This study examined the effect of two blocks of prefrontal intermittent TBS (iTBS) on cortical reactivity and working memory performance, compared to one block of iTBS and sham stimulation. We hypothesized that greater cortical effects would be obtained with two blocks of iTBS. Eighteen healthy participants attended three experimental sessions and received either sham, one block or two blocks of iTBS with a 15-min interval. Concurrent transcranial magnetic stimulation with electroencephalography (TMS-EEG) was used to assess the change in cortical reactivity via TMS-evoked potentials. Working memory performance was assessed using the N-back task. Cluster-based permutation statistics and two-way ANOVAs were used for neurophysiological and behavioural data, respectively. Both single and two blocks of iTBS resulted in a significant increase in the amplitude of TMS-evoked N100 and P200. No significant differences were observed between active conditions in either neurophysiological changes or working memory performance, and both failed to improve working memory performance relative to sham. Two blocks of iTBS did not result in stronger measured effects as compared to one block of iTBS. Future studies are needed to identify the optimal stimulation pattern in order to achieve a desired effect. It is also important to establish the best approach in quantifying neuromodulatory effects targeting the prefrontal cortex. Copyright © 2018 Elsevier Inc. All rights reserved.

Description and detection of burst events in turbulent flows

Science.gov (United States)

Schmid, P. J.; García-Gutierrez, A.; Jiménez, J.

2018-04-01

A mathematical and computational framework is developed for the detection and identification of coherent structures in turbulent wall-bounded shear flows. In a first step, this data-based technique will use an embedding methodology to formulate the fluid motion as a phase-space trajectory, from which state-transition probabilities can be computed. Within this formalism, a second step then applies repeated clustering and graph-community techniques to determine a hierarchy of coherent structures ranked by their persistencies. This latter information will be used to detect highly transitory states that act as precursors to violent and intermittent events in turbulent fluid motion (e.g., bursts). Used as an analysis tool, this technique allows the objective identification of intermittent (but important) events in turbulent fluid motion; however, it also lays the foundation for advanced control strategies for their manipulation. The techniques are applied to low-dimensional model equations for turbulent transport, such as the self-sustaining process (SSP), for varying levels of complexity.

Fuzzy correlations of gamma-ray bursts

International Nuclear Information System (INIS)

Hartmann, D.H.; Linder, E.V.; Blumenthal, G.R.

1991-01-01

The origin of gamma-ray bursts is not known, both in the sense of the nature of the source emitting the radiation and literally, the position of the burst on the sky. Lacking unambiguously identified counterparts in any wavelength band studied to date, statistical approaches are required to determine the burster distance scale. Angular correlation analysis is one of the most powerful tools in this regard. However, poor detector resolution gives large localization errors, effectively beam smearing the positions. The resulting fuzzy angular correlation function is investigated and the generic isotropization that smearing induces on any intrinsic clustering is discussed. In particular, the extent to which gamma-ray burst observations by the BATSE detector aboard the Gamma-Ray Observatory might recover an intrinsic source correlation is investigated. 16 refs

Chaos as an intermittently forced linear system.

Science.gov (United States)

Brunton, Steven L; Brunton, Bingni W; Proctor, Joshua L; Kaiser, Eurika; Kutz, J Nathan

2017-05-30

Understanding the interplay of order and disorder in chaos is a central challenge in modern quantitative science. Approximate linear representations of nonlinear dynamics have long been sought, driving considerable interest in Koopman theory. We present a universal, data-driven decomposition of chaos as an intermittently forced linear system. This work combines delay embedding and Koopman theory to decompose chaotic dynamics into a linear model in the leading delay coordinates with forcing by low-energy delay coordinates; this is called the Hankel alternative view of Koopman (HAVOK) analysis. This analysis is applied to the Lorenz system and real-world examples including Earth's magnetic field reversal and measles outbreaks. In each case, forcing statistics are non-Gaussian, with long tails corresponding to rare intermittent forcing that precedes switching and bursting phenomena. The forcing activity demarcates coherent phase space regions where the dynamics are approximately linear from those that are strongly nonlinear.The huge amount of data generated in fields like neuroscience or finance calls for effective strategies that mine data to reveal underlying dynamics. Here Brunton et al.develop a data-driven technique to analyze chaotic systems and predict their dynamics in terms of a forced linear model.

Beta burst dynamics in Parkinson's disease OFF and ON dopaminergic medication.

Science.gov (United States)

Tinkhauser, Gerd; Pogosyan, Alek; Tan, Huiling; Herz, Damian M; Kühn, Andrea A; Brown, Peter

2017-11-01

Exaggerated basal ganglia beta activity (13-35 Hz) is commonly found in patients with Parkinson's disease and can be suppressed by dopaminergic medication, with the degree of suppression being correlated with the improvement in motor symptoms. Importantly, beta activity is not continuously elevated, but fluctuates to give beta bursts. The percentage number of longer beta bursts in a given interval is positively correlated with clinical impairment in Parkinson's disease patients. Here we determine whether the characteristics of beta bursts are dependent on dopaminergic state. Local field potentials were recorded from the subthalamic nucleus of eight Parkinson's disease patients during temporary lead externalization during surgery for deep brain stimulation. The recordings took place with the patient quietly seated following overnight withdrawal of levodopa and after administration of levodopa. Beta bursts were defined by applying a common amplitude threshold and burst characteristics were compared between the two drug conditions. The amplitude of beta bursts, indicative of the degree of local neural synchronization, progressively increased with burst duration. Treatment with levodopa limited this evolution leading to a relative increase of shorter, lower amplitude bursts. Synchronization, however, was not limited to local neural populations during bursts, but also, when such bursts were cotemporaneous across the hemispheres, was evidenced by bilateral phase synchronization. The probability of beta bursts and the proportion of cotemporaneous bursts were reduced by levodopa. The percentage number of longer beta bursts in a given interval was positively related to motor impairment, while the opposite was true for the percentage number of short duration beta bursts. Importantly, the decrease in burst duration was also correlated with the motor improvement. In conclusion, we demonstrate that long duration beta bursts are associated with an increase in local and

Critical Dynamics of Burst Instabilities in the Portevin-Le Chatelier Effect

International Nuclear Information System (INIS)

D'Anna, Gianfranco; Nori, Franco

2000-01-01

We investigate the Portevin-Le Chatelier effect (PLC), by compressing Al-Mg alloys in a very large deformation range, and interpret the results from the viewpoint of phase transitions and critical phenomena. The system undergoes two dynamical phase transitions between intermittent (or ''jerky'') and ''laminar'' plastic dynamic phases. Near these two dynamic critical points, the order parameter 1/τ of the PLC effect exhibits large fluctuations, and ''critical slowing down'' (i.e., the number τ of bursts, or plastic instabilities, per unit time slows down considerably)

New decoding methods of interleaved burst error-correcting codes

Science.gov (United States)

Nakano, Y.; Kasahara, M.; Namekawa, T.

1983-04-01

A probabilistic method of single burst error correction, using the syndrome correlation of subcodes which constitute the interleaved code, is presented. This method makes it possible to realize a high capability of burst error correction with less decoding delay. By generalizing this method it is possible to obtain probabilistic method of multiple (m-fold) burst error correction. After estimating the burst error positions using syndrome correlation of subcodes which are interleaved m-fold burst error detecting codes, this second method corrects erasure errors in each subcode and m-fold burst errors. The performance of these two methods is analyzed via computer simulation, and their effectiveness is demonstrated.

Intermittent cranial lung herniation in two dogs.

Science.gov (United States)

Guglielmini, Carlo; De Simone, Antonio; Valbonetti, Luca; Diana, Alessia

2007-01-01

Two aged dogs with chronic obstructive airway disease were evaluated because of intermittent swelling of the ventral cervical region. Radiographs made at expiration and caudal positioning of the forelimbs allowed identification of intermittent cervical lung herniation of the left and right cranial lung lobe in both dogs. Pulmonary hyperinflation, increased expiratory effort, and chronic coughing were considered responsible for the lung herniation. Cervical lung hernia should be included in the differential diagnoses of intermittent cervical swelling in dogs with chronic respiratory disorders associated with increased expiratory effort and chronic coughing.

Ballerina - pirouettes in search of gamma bursts

DEFF Research Database (Denmark)

Brandt, Søren Kristian; Lund, Niels; Pedersen, Henrik

1999-01-01

The cosmological origin of gamma ray bursts has now been established with reasonable certainty, Many more bursts will need to be studied to establish the typical distance scale, and to map out the large diversity in properties which have been indicated by the first handful of events. We are propo...... are proposing Ballerina, a small satellite to provide accurate positions and new data on the gamma-ray bursts. We anticipate a detection rate an order of magnitude larger than obtained from Beppo-SAX....

External Shock in a Multi-bursting Gamma-Ray Burst: Energy Injection Phase Induced by the Later Launched Ejecta

Science.gov (United States)

Lin, Da-Bin; Huang, Bao-Quan; Liu, Tong; Gu, Wei-Min; Mu, Hui-Jun; Liang, En-Wei

2018-01-01

Central engines of gamma-ray bursts (GRBs) may be intermittent and launch several episodes of ejecta separated by a long quiescent interval. In this scenario, an external shock is formed due to the propagation of the first launched ejecta into the circum-burst medium and the later launched ejecta may interact with the external shock at a later period. Owing to the internal dissipation, the later launched ejecta may be observed at a later time (t jet). In this paper, we study the relation of t b and t jet, where t b is the collision time of the later launched ejecta with the formed external shock. It is found that the relation of t b and t jet depends on the bulk Lorentz factor (Γjet) of the later launched ejecta and the density (ρ) of the circum-burst medium. If the value of Γjet or ρ is low, the t b would be significantly larger than t jet. However, the t b ∼ t jet can be found if the value of Γjet or ρ is significantly large. Our results can explain the large lag of the optical emission relative to the γ-ray/X-ray emission in GRBs, e.g., GRB 111209A. For GRBs with a precursor, our results suggest that the energy injection into the external shock and thus more than one external-reverse shock may appear in the main prompt emission phase. According to our model, we estimate the Lorentz factor of the second launched ejecta in GRB 160625B.

Gamma ray bursts observed with WATCH‐EURECA

DEFF Research Database (Denmark)

Brandt, Søren; Lund, Niels; Castro-Tirado, A. J.

1994-01-01

The WATCH wide field x‐ray monitor has the capability of independently locating bright Gamma Ray Bursts to 1° accuracy. We report the preliminary positions of 12 Gamma Ray Bursts observed with the WATCH monitor flown on the ES spacecraft EURECA during its 11 month mission. Also the recurrence...

A Neutron Star-White Dwarf Binary Model for Repeating Fast Radio Burst 121102

Science.gov (United States)

Gu, Wei-Min; Dong, Yi-Ze; Liu, Tong; Ma, Renyi; Wang, Junfeng

2016-06-01

We propose a compact binary model for the fast radio burst (FRB) repeaters, where the system consists of a magnetic white dwarf (WD) and a neutron star (NS) with strong bipolar magnetic fields. When the WD fills its Roche lobe, mass transfer will occur from the WD to the NS through the inner Lagrange point. The accreted magnetized materials may trigger magnetic reconnection when they approach the NS surface, and therefore the electrons can be accelerated to an ultra-relativistic speed. In this scenario, the curvature radiation of the electrons moving along the NS magnetic field lines can account for the characteristic frequency and the timescale of an FRB. Owing to the conservation of angular momentum, the WD may be kicked away after a burst, and the next burst may appear when the system becomes semi-detached again through the gravitational radiation. By comparing our analyses with the observations, we show that such an intermittent Roche-lobe overflow mechanism can be responsible for the observed repeating behavior of FRB 121102.

A NEUTRON STAR–WHITE DWARF BINARY MODEL FOR REPEATING FAST RADIO BURST 121102

International Nuclear Information System (INIS)

Gu, Wei-Min; Dong, Yi-Ze; Liu, Tong; Ma, Renyi; Wang, Junfeng

2016-01-01

We propose a compact binary model for the fast radio burst (FRB) repeaters, where the system consists of a magnetic white dwarf (WD) and a neutron star (NS) with strong bipolar magnetic fields. When the WD fills its Roche lobe, mass transfer will occur from the WD to the NS through the inner Lagrange point. The accreted magnetized materials may trigger magnetic reconnection when they approach the NS surface, and therefore the electrons can be accelerated to an ultra-relativistic speed. In this scenario, the curvature radiation of the electrons moving along the NS magnetic field lines can account for the characteristic frequency and the timescale of an FRB. Owing to the conservation of angular momentum, the WD may be kicked away after a burst, and the next burst may appear when the system becomes semi-detached again through the gravitational radiation. By comparing our analyses with the observations, we show that such an intermittent Roche-lobe overflow mechanism can be responsible for the observed repeating behavior of FRB 121102.

A NEUTRON STAR–WHITE DWARF BINARY MODEL FOR REPEATING FAST RADIO BURST 121102

Energy Technology Data Exchange (ETDEWEB)

Gu, Wei-Min; Dong, Yi-Ze; Liu, Tong; Ma, Renyi; Wang, Junfeng, E-mail: guwm@xmu.edu.cn [Department of Astronomy, Xiamen University, Xiamen, Fujian 361005 (China)

2016-06-01

We propose a compact binary model for the fast radio burst (FRB) repeaters, where the system consists of a magnetic white dwarf (WD) and a neutron star (NS) with strong bipolar magnetic fields. When the WD fills its Roche lobe, mass transfer will occur from the WD to the NS through the inner Lagrange point. The accreted magnetized materials may trigger magnetic reconnection when they approach the NS surface, and therefore the electrons can be accelerated to an ultra-relativistic speed. In this scenario, the curvature radiation of the electrons moving along the NS magnetic field lines can account for the characteristic frequency and the timescale of an FRB. Owing to the conservation of angular momentum, the WD may be kicked away after a burst, and the next burst may appear when the system becomes semi-detached again through the gravitational radiation. By comparing our analyses with the observations, we show that such an intermittent Roche-lobe overflow mechanism can be responsible for the observed repeating behavior of FRB 121102.

Swift: A gamma ray burst MIDEX

International Nuclear Information System (INIS)

Barthelmy, Scott

2001-01-01

Swift is a first of its kind multiwavelength transient observatory for gamma-ray burst astronomy. It has the optimum capabilities for the next breakthroughs in determining the origin of gamma-ray bursts and their afterglows as well as using bursts to probe the early Universe. Swift will also perform the first sensitive hard X-ray survey of the sky. The mission is being developed by an international collaboration and consists of three instruments, the Burst Alert Telescope (BAT), the X-ray Telescope (XRT), and the Ultraviolet and Optical Telescope (UVOT). The BAT, a wide-field gamma-ray detector, will detect ∼1 gamma-ray burst per day with a sensitivity 5 times that of BATSE. The sensitive narrow-field XRT and UVOT will be autonomously slewed to the burst location in 20 to 70 seconds to determine 0.3-5.0 arcsec positions and perform optical, UV, and X-ray spectrophotometry. On-board measurements of redshift will also be done for hundreds of bursts. Swift will incorporate superb, low-cost instruments using existing flight-spare hardware and designs. Strong education/public outreach and follow-up programs will help to engage the public and astronomical community. Swift has been selected by NASA for development and launch in late 2003

Interaction of motor training and intermittent theta burst stimulation in modulating motor cortical plasticity: influence of BDNF Val66Met polymorphism.

Science.gov (United States)

Lee, Mina; Kim, Song E; Kim, Won Sup; Lee, Jungyeun; Yoo, Hye Kyung; Park, Kee-Duk; Choi, Kyoung-Gyu; Jeong, Seon-Yong; Kim, Byung Gon; Lee, Hyang Woon

2013-01-01

Cortical physiology in human motor cortex is influenced by behavioral motor training (MT) as well as repetitive transcranial magnetic stimulation protocol such as intermittent theta burst stimulation (iTBS). This study aimed to test whether MT and iTBS can interact with each other to produce additive changes in motor cortical physiology. We hypothesized that potential interaction between MT and iTBS would be dependent on BDNF Val66Met polymorphism, which is known to affect neuroplasticity in the human motor cortex. Eighty two healthy volunteers were genotyped for BDNF polymorphism. Thirty subjects were assigned for MT alone, 23 for iTBS alone, and 29 for MT + iTBS paradigms. TMS indices for cortical excitability and motor map areas were measured prior to and after each paradigm. MT alone significantly increased the motor cortical excitability and expanded the motor map areas. The iTBS alone paradigm also enhanced excitability and increased the motor map areas to a slightly greater extent than MT alone. A combination of MT and iTBS resulted in the largest increases in the cortical excitability, and the representational motor map expansion of MT + iTBS was significantly greater than MT or iTBS alone only in Val/Val genotype. As a result, the additive interaction between MT and iTBS was highly dependent on BDNF Val66Met polymorphism. Our results may have clinical relevance in designing rehabilitative strategies that combine therapeutic cortical stimulation and physical exercise for patients with motor disabilities.

Transcranial Magnetic Stimulation with Intermittent Theta Burst Stimulation Alters Corticospinal Output in Patients with Chronic Incomplete Spinal Cord Injury

Directory of Open Access Journals (Sweden)

Hunter J. Fassett

2017-08-01

Full Text Available Intermittent theta burst stimulation (iTBS is intended primarily to alter corticospinal excitability, creating an attractive opportunity to alter neural output following incomplete spinal cord injury (SCI. This study is the first to assess the effects of iTBS in SCI. Eight individuals with chronic incomplete SCI were studied. Sham or real iTBS was delivered (to each participant over primary motor and somatosensory cortices in separate sessions. Motor-evoked potential (MEP recruitment curves were obtained from the flexor carpi radialis muscle before and after iTBS. Results indicate similar responses for iTBS to both motor and somatosensory cortex and reduced MEPs in 56.25% and increased MEPs in 25% of instances. Sham stimulation exceeded real iTBS effects in the remaining 18.25%. It is our opinion that observing short-term neuroplasticity in corticospinal output in chronic SCI is an important advance and should be tested in future studies as an opportunity to improve function in this population. We emphasize the need to re-consider the importance of the direction of MEP change following a single session of iTBS since the relationship between MEP direction and motor function is unknown and multiple sessions of iTBS may yield very different directional results. Furthermore, we highlight the importance of including sham control in the experimental design. The fundamental point from this pilot research is that a single session of iTBS is often capable of creating short-term change in SCI. Future sham-controlled randomized trials may consider repeat iTBS sessions to promote long-term changes in corticospinal excitability.

Intermittent Theta-Burst Stimulation of the Right Dorsolateral Prefrontal Cortex to Promote Metaphor Comprehension in Parkinson Disease: A Case Study.

Science.gov (United States)

Tremblay, Christina; Monetta, Laura; Langlois, Mélanie; Schneider, Cyril

2016-01-01

This single-case research-designed study explored whether intermittent theta-burst stimulation (iTBS) of the right dorsolateral prefrontal cortex (DLPFC) could improve metaphor comprehension in people with Parkinson disease (PD) and language impairments. A right-handed participant with PD diagnosed 9 years ago, receiving long-term treatment with levodopa, and with metaphor comprehension impairment was recruited to undergo 10 sessions of sham stimulation (in 2wk), a washout period (6wk), and then 10 sessions of iTBS (in 2wk). Clinical scores of metaphor comprehension and motor evaluation (Unified Parkinson Disease Rating Scale part III) and transcranial magnetic stimulation to test the excitability of the primary motor cortex (M1) were used at baseline, postsham, post-iTBS, and at 3 follow-ups (8, 14, and 20wk post-iTBS). Metaphor comprehension was improved after iTBS, and the highest scores were obtained 8 weeks later (P=.01). This improvement was correlated with the increase of the right M1 excitability (r=-.86, P=.03) and with the decrease of transcallosal inhibition latency from the left to the right hemisphere (r=-.88, P=.02). Sham yielded no effect (P>.05). Administration of iTBS over the right DLPFC improved metaphor comprehension likely by a long-term influence on brain synaptic plasticity, including improvement of interhemispheric dialogue. More studies are warranted to confirm these findings in larger samples of participants with PD. Copyright © 2016 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

Impact of different intensities of intermittent theta burst stimulation on the cortical properties during TMS-EEG and working memory performance.

Science.gov (United States)

Chung, Sung Wook; Rogasch, Nigel C; Hoy, Kate E; Sullivan, Caley M; Cash, Robin F H; Fitzgerald, Paul B

2018-02-01

Intermittent theta burst stimulation (iTBS) is a noninvasive brain stimulation technique capable of increasing cortical excitability beyond the stimulation period. Due to the rapid induction of modulatory effects, prefrontal application of iTBS is gaining popularity as a therapeutic tool for psychiatric disorders such as depression. In an attempt to increase efficacy, higher than conventional intensities are currently being applied. The assumption that this increases neuromodulatory may be mechanistically false for iTBS. This study examined the influence of intensity on the neurophysiological and behavioural effects of iTBS in the prefrontal cortex. Sixteen healthy participants received iTBS over prefrontal cortex at either 50, 75 or 100% resting motor threshold in separate sessions. Single-pulse TMS and concurrent electroencephalography (EEG) was used to assess changes in cortical reactivity measured as TMS-evoked potentials and oscillations. The n-back task was used to assess changes in working memory performance. The data can be summarised as an inverse U-shape relationship between intensity and iTBS plastic effects, where 75% iTBS yielded the largest neurophysiological changes. Improvement in reaction time in the 3-back task was supported by the change in alpha power, however, comparison between conditions revealed no significant differences. The assumption that higher intensity results in greater neuromodulatory effects may be false, at least in healthy individuals, and should be carefully considered for clinical populations. Neurophysiological changes associated with working memory following iTBS suggest functional relevance. However, the effects of different intensities on behavioural performance remain elusive in the present healthy sample. © 2017 Wiley Periodicals, Inc.

Studying the formation of non-linear bursts in fully turbulent channel flows

Science.gov (United States)

Encinar, Miguel P.; Jimenez, Javier

2017-11-01

Linear transient growth has been suggested as a possible explanation for the intermittent behaviour, or `bursting', in shear flows with a stable mean velocity profile. Analysing fully non-linear DNS databases yields a similar Orr+lift-up mechanism, but acting on spatially localised wave packets rather than on monochromatic infinite wavetrains. The Orr mechanism requires the presence of backwards-leaning wall-normal velocity perturbations as initial condition, but the linear theory fails to clarify how these perturbations are formed. We investigate the latter in a time-resolved wavelet-filtered turbulent channel database, which allows us to assign an amplitude and an inclination angle to a flow region of selected size. This yields regions that match the dynamics of linear Orr for short times. We find that a short streamwise velocity (u) perturbation (i.e. a streak meander) consistently appears before the burst, but disappears before the burst reaches its maximum amplitude. Lift-up then generates a longer streamwise velocity perturbation. The initial streamwise velocity is also found to be backwards-leaning, contrary to the averaged energy-containing scales, which are known to be tilted forward. Funded by the ERC COTURB project.

Analysis of Burst Observations by GLAST's LAT Detector

International Nuclear Information System (INIS)

Band, David L.; Digel, Seth W.

2004-01-01

Analyzing data from GLAST's Large Area Telescope (LAT) will require sophisticated techniques. The PSF and effective area are functions of both photon energy and the position in the field-of-view. During most of the mission the observatory will survey the sky continuously, and thus, the LAT will detect each count from a source at a different detector orientation; each count requires its own response function! The likelihood as a function of celestial position and photon energy will be the foundation of the standard analysis techniques. However, the 20 MeV-300 GeV emission at the time of the ∼ 100 keV burst emission (timescale of ∼ 10 s) can be isolated and analyzed because essentially no non-burst counts are expected within a PSF radius of the burst location during the burst. Both binned and unbinned (in energy) spectral fitting will be possible. Longer timescale afterglow emission will require the likelihood analysis that will be used for persistent sources

Do lightning positive leaders really "step"?

Science.gov (United States)

Petersen, D.

2015-12-01

It has been known for some time that positive leaders exhibit impulsive charge motion and optical emissions as they extend. However, laboratory and field observations have not produced any evidence of a process analogous to the space leader mechanism of negative leader extension. Instead, observations have suggested that the positive leader tip undergoes a continuous to intermittent series of corona streamer bursts, each burst resulting in a small forward extension of the positive leader channel. Traditionally, it has been held that lightning positive leaders extend in a continuous or quasi-continuous fashion. Lately, however, many have become concerned that this position is incongruous with observations of impulsive activity during lightning positive leader extension. It is increasingly suggested that this impulsive activity is evidence that positive leaders also undergo "stepping". There are two issues that must be addressed. The first issue concerns whether or not the physical processes underlying impulsive extension in negative and positive leaders are distinct. We argue that these processes are in fact physically distinct, and offer new high-speed video evidence to support this position. The second issue regards the proper use of the term "step" as an identifier for the impulsive forward extension of a leader. Traditional use of this term has been applied only to negative leaders, due primarily to their stronger impulsive charge motions and photographic evidence of clearly discontinuous forward progression of the luminous channel. Recently, due to the increasing understanding of the distinct "space leader" process of negative leader extension, the term "step" has increasingly come to be associated with the space leader process itself. Should this emerging association, "step" = space leader attachment, be canonized? If not, then it seems reasonable to use the term "step" to describe impulsive positive leader extension. If, however, we do wish to associate the

Study on cosmic gamma bursts in the ''KONUS'' experiment

International Nuclear Information System (INIS)

Mazets, E.P.; Golenetskij, S.V.; Il'inskij, V.N.; Panov, V.N.; Aptekar', R.L.; Gur'yan, Yu.A.; Sokolov, I.A.; Sokolova, Z.Ya.; Kharitonova, T.V.

1979-01-01

Made are the investigations of cosmic gamma bursts with the help of the ''Konus'' apparatus, positioned on the ''Venera 11'' and ''Venera 12'' automatic interplanetary stations. 37 gamma bursts have been recorded in the energy range from 50 to 150 keV during the observation period from September to December 1978. Time profiles of bursts on 4, 9 and 24.11.1978 are presented. For the most events the time of burst increase and decrease constitute parts and units of seconds. Differential energy spectra are measured for all recorded bursts. In many cases the spectrum shape is similar to the grade one with the 1.5-2.3 index. In a graphical form built up are the integral distributions of gamma bursts appearence frequency in dependence on their intensity and maximum capacity in the burst peak. Galaxy coordinates of the 17-teen bursts, for which a simple localization is possible, are put on the celestial sphere map. The type of the integral distributions and the source distribution about the celestial sphere show that the gamma burst sources are whithin the Galaxy

Compact solar UV burst triggered in a magnetic field with a fan-spine topology

Science.gov (United States)

Chitta, L. P.; Peter, H.; Young, P. R.; Huang, Y.-M.

2017-09-01

Context. Solar ultraviolet (UV) bursts are small-scale features that exhibit intermittent brightenings that are thought to be due to magnetic reconnection. They are observed abundantly in the chromosphere and transition region, in particular in active regions. Aims: We investigate in detail a UV burst related to a magnetic feature that is advected by the moat flow from a sunspot towards a pore. The moving feature is parasitic in that its magnetic polarity is opposite to that of the spot and the pore. This comparably simple photospheric magnetic field distribution allows for an unambiguous interpretation of the magnetic geometry leading to the onset of the observed UV burst. Methods: We used UV spectroscopic and slit-jaw observations from the Interface Region Imaging Spectrograph (IRIS) to identify and study chromospheric and transition region spectral signatures of said UV burst. To investigate the magnetic topology surrounding the UV burst, we used a two-hour-long time sequence of simultaneous line-of-sight magnetograms from the Helioseismic and Magnetic Imager (HMI) and performed data-driven 3D magnetic field extrapolations by means of a magnetofrictional relaxation technique. We can connect UV burst signatures to the overlying extreme UV (EUV) coronal loops observed by the Atmospheric Imaging Assembly (AIA). Results: The UV burst shows a variety of extremely broad line profiles indicating plasma flows in excess of ±200 km s-1 at times. The whole structure is divided into two spatially distinct zones of predominantly up- and downflows. The magnetic field extrapolations show a persistent fan-spine magnetic topology at the UV burst. The associated 3D magnetic null point exists at a height of about 500 km above the photosphere and evolves co-spatially with the observed UV burst. The EUV emission at the footpoints of coronal loops is correlated with the evolution of the underlying UV burst. Conclusions: The magnetic field around the null point is sheared by

IDENTIFICATION OF BURSTING WATER MASER FEATURES IN ORION KL

International Nuclear Information System (INIS)

Hirota, Tomoya; Honma, Mareki; Kim, Mi Kyoung; Kobayashi, Hideyuki; Shibata, Katsunori M.; Tsuboi, Masato; Fujisawa, Kenta; Kawaguchi, Noriyuki; Imai, Hiroshi; Omodaka, Toshihiro; Shimoikura, Tomomi; Yonekura, Yoshinori

2011-01-01

In 2011 February, a burst event of the H 2 O maser in Orion KL (Kleinmann-Low object) has started after a 13 year silence. This is the third time such phenomena has been detected in Orion KL, followed by the events in 1979-1985 and 1998. We have carried out astrometric observations of the bursting H 2 O maser features in Orion KL with the VLBI Exploration of Radio Astrometry (VERA), a Japanese very long baseline interferometry network dedicated for astrometry. The total flux of the bursting feature at the local standard of rest (LSR) velocity of 7.58 km s -1 reaches 4.4 x 10 4 Jy in 2011 March. The intensity of the bursting feature is three orders of magnitude larger than that of the same velocity feature in the quiescent phase in 2006. Two months later, another new feature appears at the LSR velocity of 6.95 km s -1 in 2011 May, separated by 12 mas north of the 7.58 km s -1 feature. Thus, the current burst occurs at two spatially different features. The bursting masers are elongated along the northwest-southeast direction as reported in the previous burst in 1998. We determine the absolute positions of the bursting features for the first time ever with a submilliarcsecond (mas) accuracy. Their positions are coincident with the shocked molecular gas called the Orion Compact Ridge. We tentatively detect the absolute proper motions of the bursting features toward the southwest direction. It is most likely that the outflow from the radio source I or another young stellar object interacting with the Compact Ridge is a possible origin of the H 2 O maser burst.

Balloon observation of gamma-ray burst

International Nuclear Information System (INIS)

Nishimura, Jun; Fujii, Masami; Yamagami, Takamasa; Oda, Minoru; Ogawara, Yoshiaki

1978-01-01

Cosmic gamma-ray burst is an interesting high energy astrophysical phenomenon, but the burst mechanism has not been well understood. Since 1975, long duration balloon flight has been conducted to search for gamma-ray bursts and to determine the source locations. A rotating cross-modulation collimator was employed to determine the locations of sources, and four NaI(Tl) scintillation counters were employed to detect hard X-ray with energy from 20 to 200 keV. The balloon light was performed at altitude of 8.3 mb from September 28, 1977, and the observation time of 79 hours was achieved. In this experiment, the monitor counter was not mounted. The count increase was observed at 16 h 22 m 31 s JST on October 1, 1977. The event disappeared after 1 sec. The total flux is estimated to be 1.6 x 10 -6 erg/cm 2 sec at the top of the atmosphere. When this event was observed, the solar-terrestrial environment was also quiet. Thus, this event was attributed to a small gamma-ray burst. Unfortunately, the duration of the burst was so short that the position of the burst source was not able to be determined. (Yoshimori, M.)

The physiological basis of the effects of intermittent theta burst stimulation of the human motor cortex.

Science.gov (United States)

Di Lazzaro, V; Pilato, F; Dileone, M; Profice, P; Oliviero, A; Mazzone, P; Insola, A; Ranieri, F; Meglio, M; Tonali, P A; Rothwell, J C

2008-08-15

Theta burst stimulation (TBS) is a form of repetitive transcranial magnetic stimulation (TMS). When applied to motor cortex it leads to after-effects on corticospinal and corticocortical excitability that may reflect LTP/LTD-like synaptic effects. An inhibitory form of TBS (continuous, cTBS) suppresses MEPs, and spinal epidural recordings show this is due to suppression of the I1 volley evoked by TMS. Here we investigate whether the excitatory form of TBS (intermittent, iTBS) affects the same I-wave circuitry. We recorded corticospinal volleys evoked by single pulse TMS of the motor cortex before and after iTBS in three conscious patients who had an electrode implanted in the cervical epidural space for the control of pain. As in healthy subjects, iTBS increased MEPs, and this was accompanied by a significant increase in the amplitude of later I-waves, but not the I1 wave. In two of the patients we tested the excitability of the contralateral cortex and found a significant suppression of the late I-waves. The extent of the changes varied between the three patients, as did their age. To investigate whether age might be a significant contributor to the variability we examined the effect of iTBS on MEPs in 18 healthy subjects. iTBS facilitated MEPs evoked by TMS of the conditioned hemisphere and suppressed MEPs evoked by stimulation of the contralateral hemisphere. There was a slight but non-significant decline in MEP facilitation with age, suggesting that interindividual variability was more important than age in explaining our data. In a subgroup of 10 subjects we found that iTBS had no effect on the duration of the ipsilateral silent period suggesting that the reduction in contralateral MEPs was not due to an increase in ongoing transcallosal inhibition. In conclusion, iTBS affects the excitability of excitatory synaptic inputs to pyramidal tract neurones that are recruited by a TMS pulse, both in the stimulated hemisphere and in the contralateral hemisphere

Energy intermittency

CERN Document Server

Sorensen, Bent

2014-01-01

The first book to consider intermittency as a key point of an energy system, Energy Intermittency describes different levels of variability for traditional and renewable energy sources, presenting detailed solutions for handling energy intermittency through trade, collaboration, demand management, and active energy storage. Addressing energy supply intermittency systematically, this practical text:Analyzes typical time-distributions and intervals between episodes of demand-supply mismatch and explores their dependence on system layouts and energy source characteristicsSimulates scenarios regar

Gamma-ray bursts observed by the watch experiment

DEFF Research Database (Denmark)

Lund, Niels; Brandt, Søren; Castro-Tirado, A. J.

1991-01-01

After two years in orbit the WATCH instruments on the GRANAT space observatory have localized seven gamma burst sources with better than 1° accuracy. In several cases, follow‐up observations with Schmidt telescopes have been made within a few days. Some of the bursts have also been detected...... by the distant space probes PVO and ULYSSES and there are, therefore, good prospects for obtaining much improved positions using the burst arrival times. The existence of the almost concurrent Schmidt plates could then become particularly interesting....

Intermittent Theta-Burst Transcranial Magnetic Stimulation Alters Electrical Properties of Fast-Spiking Neocortical Interneurons in an Age-Dependent Fashion.

Science.gov (United States)

Hoppenrath, Kathrin; Härtig, Wolfgang; Funke, Klaus

2016-01-01

Modulation of human cortical excitability by repetitive transcranial magnetic stimulation (rTMS) appears to be in part related to changed activity of inhibitory systems. Our own studies showed that intermittent theta-burst stimulation (iTBS) applied via rTMS to rat cortex primarily affects the parvalbumin-expressing (PV) fast-spiking interneurons (FSIs), evident via a strongly reduced PV expression. We further found the iTBS effect on PV to be age-dependent since no reduction in PV could be induced before the perineuronal nets (PNNs) of FSIs start to grow around postnatal day (PD) 30. To elucidate possible iTBS-induced changes in the electrical properties of FSIs and cortical network activity during cortical critical period, we performed ex vivo-in vitro whole-cell patch clamp recordings from pre-labeled FSIs in the current study. FSIs of verum iTBS-treated rats displayed a higher excitability than sham-treated controls at PD29-38, evident as higher rates of induced action potential firing at low current injections (100-200 pA) and a more depolarized resting membrane potential. This effect was absent in younger (PD26-28) and older animals (PD40-62). Slices of verum iTBS-treated rats further showed higher rates of spontaneous excitatory postsynaptic currents (sEPSCs). Based on these and previous findings we conclude that FSIs are particularly sensitive to TBS during early cortical development, when FSIs show an activity-driven step of maturation which is paralleled by intense growth of the PNNs and subsequent closure of the cortical critical period. Although to be proven further, rTMS may be a possible early intervention to compensate for hypo-activity related mal-development of cortical neuronal circuits.

Interaction of motor training and intermittent theta burst stimulation in modulating motor cortical plasticity: influence of BDNF Val66Met polymorphism.

Directory of Open Access Journals (Sweden)

Mina Lee

Full Text Available Cortical physiology in human motor cortex is influenced by behavioral motor training (MT as well as repetitive transcranial magnetic stimulation protocol such as intermittent theta burst stimulation (iTBS. This study aimed to test whether MT and iTBS can interact with each other to produce additive changes in motor cortical physiology. We hypothesized that potential interaction between MT and iTBS would be dependent on BDNF Val66Met polymorphism, which is known to affect neuroplasticity in the human motor cortex. Eighty two healthy volunteers were genotyped for BDNF polymorphism. Thirty subjects were assigned for MT alone, 23 for iTBS alone, and 29 for MT + iTBS paradigms. TMS indices for cortical excitability and motor map areas were measured prior to and after each paradigm. MT alone significantly increased the motor cortical excitability and expanded the motor map areas. The iTBS alone paradigm also enhanced excitability and increased the motor map areas to a slightly greater extent than MT alone. A combination of MT and iTBS resulted in the largest increases in the cortical excitability, and the representational motor map expansion of MT + iTBS was significantly greater than MT or iTBS alone only in Val/Val genotype. As a result, the additive interaction between MT and iTBS was highly dependent on BDNF Val66Met polymorphism. Our results may have clinical relevance in designing rehabilitative strategies that combine therapeutic cortical stimulation and physical exercise for patients with motor disabilities.

Enhanced motor skill acquisition in the non-dominant upper extremity using intermittent theta burst stimulation and transcranial direct current stimulation.

Science.gov (United States)

Butts, Raymond J; Kolar, Melissa B; Newman-Norlund, Roger D

2014-01-01

Individuals suffering from motor impairments often require physical therapy (PT) to help improve their level of function. Previous investigations suggest that both intermittent theta burst stimulation (iTBS) and bihemispheric transcranial direct current stimulation (tDCS) may increase the speed and extent of motor learning/relearning. The purpose of the current study was to explore the feasibility and effectiveness of a novel, non-invasive brain stimulation approach that combined an iTBS primer, and bihemispheric stimulation coupled with motor training. We hypothesized that individuals exposed to this novel treatment would make greater functional improvements than individuals undergoing sham stimulation when tested immediately following, 24-h, and 7-days post-training. A total of 26 right-handed, healthy young adults were randomly assigned to either a treatment (n = 15) or control group (n = 12). iTBS (20 trains of 10 pulse triplets each delivered at 80% active motor threshold (AMT) / 50 Hz over 191.84 s) and bihemispheric tDCS (1.0 ma for 20 min) were used as a primer to, and in conjunction with, 20 min of motor training, respectively. Our primary outcome measure was performance on the Jebsen-Taylor Hand Function (JTHF) test. Participants tolerated the combined iTBS/bihemispheric stimulation treatment without complaint. While performance gains in the sham and stimulation group were not significant immediately after training, they were nearly significant 24-h post training (p = 0.055), and were significant at 7-days post training (p iTBS/bihemispheric stimulation protocol is both feasible and effective. Future research should examine the mechanistic explanation of this approach as well as the potential of using this approach in clinical populations.

Neutron stars as X-ray burst sources. II. Burst energy histograms and why they burst

International Nuclear Information System (INIS)

Baan, W.A.

1979-01-01

In this work we explore some of the implications of a model for X-ray burst sources where bursts are caused by Kruskal-Schwarzschild instabilities at the magnetopause of an accreting and rotating neutron star. A number of simplifying assumptions are made in order to test the model using observed burst-energy histograms for the rapid burster MXB 1730--335. The predicted histograms have a correct general shape, but it appears that other effects are important as well, and that mode competition, for instance, may suppress the histograms at high burst energies. An explanation is ventured for the enhancement in the histogram at the highest burst energies, which produces the bimodal shape in high accretion rate histograms. Quantitative criteria are given for deciding when accreting neutron stars are steady sources or burst sources, and these criteria are tested using the X-ray pulsars

Relativistic effects in gamma-ray bursts

International Nuclear Information System (INIS)

Eriksen, Erik; Groen, Oeyvind

1999-01-01

According to recent models of the sources of gamma-ray bursts the extremely energetic emission is caused by shells expanding with ultrarelativistic velocity. With the recent identification of optical sources at the positions of some gamma-ray bursts these ''fireball'' models have acquired an actuality that invites to use them as a motivating application when teaching special relativity. We demonstrate several relativistic effects associated with these models which are very pronounced due to the great velocity of the shell. For example a burst lasting for a month in the rest frame of an element of the shell lasts for a few seconds only, in the rest frame of our detector. It is shown how the observed properties of a burst are modified by aberration and the Doppler effect. The apparent luminosity as a function of time is calculated. Modifications due to the motion of the star away from the observer are calculated. (Author)

High-dose phenobarbital with intermittent short-acting barbiturates for acute encephalitis with refractory, repetitive partial seizures.

Science.gov (United States)

Uchida, Takashi; Takayanagi, Masaru; Kitamura, Taro; Nishio, Toshiyuki; Numata, Yurika; Endo, Wakaba; Haginoya, Kazuhiro; Ohura, Toshihiro

2016-08-01

Acute encephalitis with refractory, repetitive partial seizures (AERRPS) is characterized by repetitive seizures during the acute and chronic phases and has a poor neurological outcome. Burst-suppression coma via continuous i.v. infusion of a short-acting barbiturate is used to terminate refractory seizures, but the severe side-effects of short-acting barbiturates are problematic. We report on a 9-year-old boy with AERRPS who was effectively treated with very-high-dose phenobarbital (VHDPB) combined with intermittent short-acting barbiturates. VHDPB side-effects were mild, especially compared with those associated with continuous i.v. infusion of short-acting barbiturates (dosage, 40-75 mg/kg/day; maximum blood level, 290 μg/mL). Using VHDPB as the main treatment, short-acting barbiturates were used intermittently and in small amounts. This is the first report to show that VHDPB, combined with intermittent short-acting barbiturates, can effectively treat AERRPS. After treatment, convulsions were suppressed and daily life continued, but intellectual impairment and high-level dysfunction remained. © 2016 Japan Pediatric Society.

BALLERINA - Pirouettes in search of gamma burst sources

International Nuclear Information System (INIS)

Brandt, Soeren; Lund, Niels

1999-01-01

The cosmological origin of gamma-ray bursts (GRBs) has now been established with reasonable certainty. Many more bursts will need to be studied to establish the typical distance scale, and to map out the large variability in properties, which have been indicated by the first handful of events. We are proposing BALLERINA, a small satellite to provide accurate gamma burst positions at a rate an order of magnitude larger than from Beppo-SAX. On the experimental side, it remains a challenge to ensure the earliest detection of the X-ray afterglow. The mission proposed here allows for the first time systematic studies of the soft X-ray emission in the time interval from only a few minutes after the onset of the burst to a few hours later. In addition to positions of GRBs with accuracy better than 1'reported to the ground within a few minutes of the burst, essential for follow-up work, BALLERINA will on its own provide observations in an uncharted region of parameter space. Secondary objectives of the BALLERINA mission includes observations of the earliest phases of the outbursts of X-ray novae and other X-ray transients. BALLERINA is one of four missions currently under study for the Danish Small Satellite Program. The selection will be announced in 1999 for a planned launch in 2002-2003

LOCALIZATION OF GAMMA-RAY BURSTS USING THE FERMI GAMMA-RAY BURST MONITOR

Energy Technology Data Exchange (ETDEWEB)

Connaughton, V.; Briggs, M. S.; Burgess, J. M. [CSPAR and Physics Department, University of Alabama in Huntsville, 320 Sparkman Drive, Huntsville, AL 35899 (United States); Goldstein, A.; Wilson-Hodge, C. A. [Astrophysics Office, ZP12, NASA/Marshall Space Flight Center, Huntsville, AL 35812 (United States); Meegan, C. A.; Jenke, P.; Pelassa, V.; Xiong, S.; Bhat, P. N. [CSPAR, University of Alabama in Huntsville, 320 Sparkman Drive, Huntsville, AL 35899 (United States); Paciesas, W. S. [Universities Space Research Association, Huntsville, AL (United States); Preece, R. D. [Department of Space Science, University of Alabama in Huntsville, 320 Sparkman Drive, Huntsville, AL 35899 (United States); Gibby, M. H. [Jacobs Technology, Inc., Huntsville, AL (United States); Greiner, J.; Yu, H.-F. [Max-Planck-Institut für extraterrestrische Physik, Giessenbachstrasse 1, D-85748 Garching (Germany); Gruber, D. [Planetarium Südtirol, Gummer 5, I-39053 Karneid (Italy); Kippen, R. M. [Los Alamos National Laboratory, NM 87545 (United States); Byrne, D.; Fitzpatrick, G.; Foley, S., E-mail: valerie@nasa.gov [School of Physics, University College Dublin, Belfield, Stillorgan Road, Dublin 4 (Ireland); and others

2015-02-01

The Fermi Gamma-ray Burst Monitor (GBM) has detected over 1400 gamma-ray bursts (GRBs) since it began science operations in 2008 July. We use a subset of over 300 GRBs localized by instruments such as Swift, the Fermi Large Area Telescope, INTEGRAL, and MAXI, or through triangulations from the InterPlanetary Network, to analyze the accuracy of GBM GRB localizations. We find that the reported statistical uncertainties on GBM localizations, which can be as small as 1°, underestimate the distance of the GBM positions to the true GRB locations and we attribute this to systematic uncertainties. The distribution of systematic uncertainties is well represented (68% confidence level) by a 3.°7 Gaussian with a non-Gaussian tail that contains about 10% of GBM-detected GRBs and extends to approximately 14°. A more complex model suggests that there is a dependence of the systematic uncertainty on the position of the GRB in spacecraft coordinates, with GRBs in the quadrants on the Y axis better localized than those on the X axis.

Enhanced Motor Skill Acquisition in the Non-dominant Upper Extremity using Intermittent Theta Burst Stimulation and Transcranial Direct Current Stimulation

Directory of Open Access Journals (Sweden)

Ray eButts

2014-06-01

Full Text Available Individuals suffering from motor impairments often require physical therapy (PT to help improve their level of function. Previous investigations suggest that both intermittent theta burst stimulation (iTBS and bihemispheric transcranial direct current stimulation may increase the speed and extent of motor learning/relearning and that this increase may be related to brain derived neurotrophic factor (BDNF. The purpose of the current study was to explore the feasibility and effectiveness of a novel, non-invasive brain stimulation approach that combined an iTBS primer, and bihemispheric stimulation coupled with motor training. We hypothesized that individuals exposed to this novel treatment would make greater functional improvements than individuals undergoing sham stimulation when tested immediately following, 24-hours, and 7-days post-training. A total of 26 right-handed, healthy young adults were randomly assigned to either a treatment (n = 15 or control group (n = 12. iTBS (20 trains of 10 pulse triplets each delivered at 80% AMT / 50Hz over 191.84 seconds and bihemispheric tDCS (1.0 ma for 20 minutes were used as a primer to, and in conjunction with, 20 minutes of motor training, respectively. Our primary outcome measure was performance on the Jebsen-Taylor Hand Function Test. Participants tolerated the combined iTBS/bihemispheric stimulation treatment without complaint. While performance gains in the sham and stimulation group were not significant immediately after training, they were nearly significant 24-hours post training (p = 0.055, and were significant at 7-days post training (p < 0.05. These results suggest that the combined iTBS/bihemispheric stimulation protocol is both feasible and effective. Future research should examine the mechanistic explanation of this approach as well as the potential of using this approach in clinical populations.

Modulation of left primary motor cortex excitability after bimanual training and intermittent theta burst stimulation to left dorsal premotor cortex.

Science.gov (United States)

Neva, Jason L; Vesia, Michael; Singh, Amaya M; Staines, W Richard

2014-03-15

Bimanual visuomotor movement training (BMT) enhances the excitability of human preparatory premotor and primary motor (M1) cortices compared to unimanual movement. This occurs when BMT involves mirror symmetrical movements of both upper-limbs (in-phase) but not with non-symmetrical movements (anti-phase). The neural mechanisms mediating the effect of BMT is unclear, but may involve interhemispheric connections between homologous M1 representations as well as the dorsal premotor cortices (PMd). The purpose of this study is to assess how intermittent theta burst stimulation (iTBS) of the left PMd affects left M1 excitability, and the possible combined effects of iTBS to left PMd applied before a single session of BMT. Left M1 excitability was quantified using transcranial magnetic stimulation (TMS) in terms of both the amplitudes and spatial extent of motor evoked potentials (MEPs) for the extensor carpi radialis (ECR) before and multiple time points following (1) BMT, (2) iTBS to left PMd or (3) iTBS to left PMd and BMT. Although there was not a greater increase in either specific measure of M1 excitability due to the combination of the interventions, iTBS applied before BMT showed that both the spatial extent and global MEP amplitude for the ECR became larger in parallel, whereas the spatial extent was enhanced with BMT alone and global MEP amplitude was enhanced with iTBS to left PMd alone. These results suggest that the modulation of rapid functional M1 excitability associated with BMT and iTBS of the left PMd could operate under related early markers of neuro-plastic mechanisms, which may be expressed in concurrent and distinct patterns of M1 excitability. Critically, this work may guide rehabilitation training and stimulation techniques that modulate cortical excitability after brain injury. Copyright © 2013 Elsevier B.V. All rights reserved.

Continuous and intermittent transcranial magnetic theta burst stimulation modify tactile learning performance and cortical protein expression in the rat differently.

Science.gov (United States)

Mix, Annika; Benali, Alia; Eysel, Ulf T; Funke, Klaus

2010-11-01

Repetitive transcranial magnetic stimulation (rTMS) can modulate cortical excitability in a stimulus-frequency-dependent manner. Two kinds of theta burst stimulation (TBS) [intermittent TBS (iTBS) and continuous TBS (cTBS)] modulate human cortical excitability differently, with iTBS increasing it and cTBS decreasing it. In rats, we recently showed that this is accompanied by changes in the cortical expression of proteins related to the activity of inhibitory neurons. Expression levels of the calcium-binding protein parvalbumin (PV) and of the 67-kDa isoform of glutamic acid decarboxylase (GAD67) were strongly reduced following iTBS, but not cTBS, whereas both increased expression of the 65-kDa isoform of glutamic acid decarboxylase. In the present study, to investigate possible functional consequences, we applied iTBS and cTBS to rats learning a tactile discrimination task. Conscious rats received either verum or sham rTMS prior to the task. Finally, to investigate how rTMS and learning effects interact, protein expression was determined for cortical areas directly involved in the task and for those either not, or indirectly, involved. We found that iTBS, but not cTBS, improved learning and strongly reduced cortical PV and GAD67 expression. However, the combination of learning and iTBS prevented this effect in those cortical areas involved in the task, but not in unrelated areas. We conclude that the improved learning found following iTBS is a result of the interaction of two effects, possibly in a homeostatic manner: a general weakening of inhibition mediated by the fast-spiking interneurons, and re-established activity in those neurons specifically involved in the learning task, leading to enhanced contrast between learning-induced and background activity. © 2010 The Authors. European Journal of Neuroscience © 2010 Federation of European Neuroscience Societies and Blackwell Publishing Ltd.

Reduction in cortical parvalbumin expression due to intermittent theta-burst stimulation correlates with maturation of the perineuronal nets in young rats.

Science.gov (United States)

Mix, Annika; Hoppenrath, Kathrin; Funke, Klaus

2015-01-01

We recently showed that intermittent theta-burst stimulation (iTBS) using transcranial magnetic stimulation strongly reduces the number of rat neocortical interneurons expressing glutamic acid decarboxylase 67 kDa (GAD67) and parvalbumin (PV), indicating changed activity of fast-spiking (FS) interneurons. In advance of in vitro studies intended to characterize changes in electrical properties of FS interneurons under these conditions, we tested whether the iTBS effect is age-dependent. Conscious Sprague-Dawley rats aged between 28 and 90 days received three blocks of iTBS at 15 min intervals. We found that iTBS-related reduction in PV+ cells was absent up to an age of 32 days, then gradually increased, and approached a maximum of about 40% reduction at an age of about 40 days. The relative number of cells expressing PV (PV+, 8-9%) did not change with age in sham-controls and also the increase in cortical c-Fos expression induced by iTBS was not principally age-dependent. However, a prominent growth of the perineuronal nets, typically surrounding the PV+ cells, exactly paralleled the increase in the iTBS effect. Based on these findings, we conclude that the functional development of the inhibitory network of PV+ interneurons with regard to intracortical synaptic connectivity is not sufficiently matured in rats younger than 35 d to enable activity-dependent modifications during iTBS. Outgrowth of the perineuronal nets and associated maturation of excitatory cortical inputs, as is characteristic for the critical cortical period, may take place before PV+ interneurons can be sufficiently activated via repetitive transcranial magnetic stimulation, allowing plastic changes of molecular phenotype and likely also synaptic plasticity. © 2014 Wiley Periodicals, Inc.

Flow-synchronized nasal intermittent positive pressure ventilation in the preterm infant: development of a project

Directory of Open Access Journals (Sweden)

Corrado Moretti

2013-06-01

Full Text Available This manuscript describes the experience of our team in developing a flow-triggered nasal respiratory support for the neonate and its related clinical applications. Although mechanical ventilation (MV via an endotracheal tube has undoubtedly led to improvement in neonatal survival in the last 40 years, the prolonged use of this technique may predispose the infant to the development of many possible complications, first of all, bronchopulmonary dysplasia (BPD. Avoiding mechanical ventilation is thought to be a critical goal, and different modes of non invasive respiratory support may reduce the intubation rate: nasal continuous positive airway pressure (NCPAP, nasal intermittent positive pressure ventilation (NIPPV and its more advantageous form, synchronized nasal intermittent positive pressure ventilation (SNIPPV. SNIPPV was initially performed by a capsule placed on the baby’s abdomen. To overcome the disadvantages of the abdominal capsule, our team decided to create a flow-sensor that could be interposed between the nasal prongs and the Y piece. Firstly we developed a hot-wire flow-sensor to trigger the ventilator and we showed that flow-SNIPPV can support the inspiratory effort in the post-extubation period more effectively than NCPAP. But, although accurate, the proper functioning of the hot-wire flow-sensor was easily compromised by secretions or moisture, and therefore we started to use as flow-sensor a simpler differential pressure transducer. In a following trial using the new device, we were able to demonstrate that flow-SNIPPV was more effective than conventional NCPAP in decreasing extubation failure in preterm infants who had been ventilated for respiratory distress syndrome (RDS. More recently we used flow-SNIPPV as the primary mode of ventilation, after surfactant replacement, reducing MV need and favorably affecting short-term morbidities of treated premature infants. We also successfully applied SNIPPV to treat apnea of

Cosmic gamma-ray burst

International Nuclear Information System (INIS)

Yamagami, Takamasa

1985-01-01

Ballon experiments for searching gamma-ray burst were carried out by employing rotating-cross modulation collimators. From a very long observation of total 315 hours during 1975 to 1979, three gamma-ray intensity anomalies were observed which were speculated as a gamma-ray burst. As for the first gamma-ray intensity anomaly observed in 1975, the burst source could be located precisely but the source, heavenly body, could not be specified. Gamma-ray burst source estimation was made by analyzing distribution of burst source in the celestial sphere, burst size distribution, and burst peak. Using the above-mentioned data together with previously published ones, apparent inconsistency was found between the observed results and the adopted theory that the source was in the Galaxy, and this inconsistency was found due to the different time profiles of the burst observed with instruments of different efficiency. It was concluded by these analysis results that employment of logN - logP (relation between burst frequency and burst count) was better than that of logN - logS (burst size) in the examination of gamma-ray burst because the former was less uncertain than the latter. Analyzing the author's observed gamma-ray burst data and the related published data, it was clarified that the burst distribution was almost P -312 for the burst peak value larger than 10 -6 erg/cm 2 .sec. The author could indicate that the calculated celestial distribution of burst source was consistent with the observed results by the derivation using the logN - logP relationship and that the burst larger than 10 -6 erg/cm 2 .sec happens about one thousand times a year, about ten times of the previous value. (Takagi, S.)

Galactic distribution of X-ray burst sources

International Nuclear Information System (INIS)

Lewin, W.H.G.; Hoffman, J.A.; Doty, J.; Clark, G.W.; Swank, J.H.; Becker, R.H.; Pravdo, S.H.; Serlemitsos, P.J.

1977-01-01

It is stated that 18 X-ray burst sources have been observed to date, applying the following definition for these bursts - rise times of less than a few seconds, durations of seconds to minutes, and recurrence in some regular pattern. If single burst events that meet the criteria of rise time and duration, but not recurrence are included, an additional seven sources can be added. A sky map is shown indicating their positions. The sources are spread along the galactic equator and cluster near low galactic longitudes, and their distribution is different from that of the observed globular clusters. Observations based on the SAS-3 X-ray observatory studies and the Goddard X-ray Spectroscopy Experiment on OSO-9 are described. The distribution of the sources is examined and the effect of uneven sky exposure on the observed distribution is evaluated. It has been suggested that the bursts are perhaps produced by remnants of disrupted globular clusters and specifically supermassive black holes. This would imply the existence of a new class of unknown objects, and at present is merely an ad hoc method of relating the burst sources to globular clusters. (U.K.)

The Impact of Single Session Intermittent Theta-Burst Stimulation over the Dorsolateral Prefrontal Cortex and Posterior Superior Temporal Sulcus on Adults with Autism Spectrum Disorder

Directory of Open Access Journals (Sweden)

Hsing-Chang Ni

2017-05-01

Full Text Available Intermittent theta burst stimulation (iTBS, a patterned repetitive transcranial magnetic stimulation, was applied over the posterior superior temporal sulcus (pSTS or dorsolateral prefrontal cortex (DLPFC to explore its impact in adults with autism spectrum disorder (ASD. Among 25 adults with ASD, 19 (mean age: 20.8 years completed the randomized, sham-controlled, crossover trial. Every participant received iTBS over the bilateral DLPFC, bilateral pSTS and inion (as a sham control stimulation in a randomized order with a 1-week interval. Neuropsychological functions were assessed using the Conners' Continuous Performance Test (CCPT and the Wisconsin Card Sorting Test (WCST. Behavioral outcomes were measured using the Yale-Brown Obsessive Compulsive Scale (Y-BOCS and the Social Responsiveness Scale (SRS. In comparison to that in the sham stimulation, the reaction time in the CCPT significantly decreased following single DLPFC session (p = 0.04, effect size = 0.71 while there were no significant differences in the CCPT and WCST following single pSTS session. Besides, the results in behavioral outcomes were inconsistent and had discrepancy between reports of parents and patients. In conclusion, a single session of iTBS over the bilateral DLPFC may alter the neuropsychological function in adults with ASD. The impacts of multiple-sessions iTBS over the DLPFC or pSTS deserve further investigations.

CAN ULTRAHIGH-ENERGY COSMIC RAYS COME FROM GAMMA-RAY BURSTS? COSMIC RAYS BELOW THE ANKLE AND GALACTIC GAMMA-RAY BURSTS

International Nuclear Information System (INIS)

Eichler, David; Pohl, Martin

2011-01-01

The maximum cosmic-ray energy achievable by acceleration by a relativistic blast wave is derived. It is shown that forward shocks from long gamma-ray bursts (GRBs) in the interstellar medium accelerate protons to large enough energies, and have a sufficient energy budget, to produce the Galactic cosmic-ray component just below the ankle at 4 x 10 18 eV, as per an earlier suggestion. It is further argued that, were extragalactic long GRBs responsible for the component above the ankle as well, the occasional Galactic GRB within the solar circle would contribute more than the observational limits on the outward flux from the solar circle, unless an avoidance scenario, such as intermittency and/or beaming, allows the present-day local flux to be less than 10 -3 of the average. Difficulties with these avoidance scenarios are noted.

Intermittent search strategies

Science.gov (United States)

Bénichou, O.; Loverdo, C.; Moreau, M.; Voituriez, R.

2011-01-01

This review examines intermittent target search strategies, which combine phases of slow motion, allowing the searcher to detect the target, and phases of fast motion during which targets cannot be detected. It is first shown that intermittent search strategies are actually widely observed at various scales. At the macroscopic scale, this is, for example, the case of animals looking for food; at the microscopic scale, intermittent transport patterns are involved in a reaction pathway of DNA-binding proteins as well as in intracellular transport. Second, generic stochastic models are introduced, which show that intermittent strategies are efficient strategies that enable the minimization of search time. This suggests that the intrinsic efficiency of intermittent search strategies could justify their frequent observation in nature. Last, beyond these modeling aspects, it is proposed that intermittent strategies could also be used in a broader context to design and accelerate search processes.

Swift pointing and gravitational-wave bursts from gamma-ray burst events

International Nuclear Information System (INIS)

Sutton, Patrick J; Finn, Lee Samuel; Krishnan, Badri

2003-01-01

The currently accepted model for gamma-ray burst phenomena involves the violent formation of a rapidly rotating solar-mass black hole. Gravitational waves should be associated with the black-hole formation, and their detection would permit this model to be tested. Even upper limits on the gravitational-wave strength associated with gamma-ray bursts could constrain the gamma-ray burst model. This requires joint observations of gamma-ray burst events with gravitational and gamma-ray detectors. Here we examine how the quality of an upper limit on the gravitational-wave strength associated with gamma-ray bursts depends on the relative orientation of the gamma-ray-burst and gravitational-wave detectors, and apply our results to the particular case of the Swift Burst-Alert Telescope (BAT) and the LIGO gravitational-wave detectors. A result of this investigation is a science-based 'figure of merit' that can be used, together with other mission constraints, to optimize the pointing of the Swift telescope for the detection of gravitational waves associated with gamma-ray bursts

Intermittent Theta Burst Over M1 May Increase Peak Power of a Wingate Anaerobic Test and Prevent the Reduction of Voluntary Activation Measured with Transcranial Magnetic Stimulation.

Science.gov (United States)

Giboin, Louis-Solal; Thumm, Patrick; Bertschinger, Raphael; Gruber, Markus

2016-01-01

Despite the potential of repetitive transcranial magnetic stimulation (rTMS) to improve performances in patients suffering from motor neuronal afflictions, its effect on motor performance enhancement in healthy subjects during a specific sport task is still unknown. We hypothesized that after an intermittent theta burst (iTBS) treatment, performance during the Wingate Anaerobic Test (WAnT) will increase and supraspinal fatigue following the exercise will be lower in comparison to a control treatment. Ten subjects participated in two randomized experiments consisting of a WAnT 5 min after either an iTBS or a control treatment. We determined voluntary activation (VA) of the right knee extensors with TMS (VATMS) and with peripheral nerve stimulation (VAPNS) of the femoral nerve, before and after the WAnT. T-tests were applied to the WAnT results and a two way within subject ANOVA was applied to VA results. The iTBS treatment increased the peak power and the maximum pedalling cadence and suppressed the reduction of VATMS following the WAnT compared to the control treatment. No behavioral changes related to fatigue (mean power and fatigue index) were observed. These results indicate for the first time that iTBS could be used as a potential intervention to improve anaerobic performance in a sport specific task.

Comparing microbial water quality in an intermittent and continuous piped water supply.

Science.gov (United States)

Kumpel, Emily; Nelson, Kara L

2013-09-15

Supplying piped water intermittently is a common practice throughout the world that increases the risk of microbial contamination through multiple mechanisms. Converting an intermittent supply to a continuous supply has the potential to improve the quality of water delivered to consumers. To understand the effects of this upgrade on water quality, we tested samples from reservoirs, consumer taps, and drinking water provided by households (e.g. from storage containers) from an intermittent and continuous supply in Hubli-Dharwad, India, over one year. Water samples were tested for total coliform, Escherichia coli, turbidity, free chlorine, and combined chlorine. While water quality was similar at service reservoirs supplying the continuous and intermittent sections of the network, indicator bacteria were detected more frequently and at higher concentrations in samples from taps supplied intermittently compared to those supplied continuously (p supply, with 0.7% of tap samples positive compared to 31.7% of intermittent water supply tap samples positive for E. coli. In samples from both continuously and intermittently supplied taps, higher concentrations of total coliform were measured after rainfall events. While source water quality declined slightly during the rainy season, only tap water from intermittent supply had significantly more indicator bacteria throughout the rainy season compared to the dry season. Drinking water samples provided by households in both continuous and intermittent supplies had higher concentrations of indicator bacteria than samples collected directly from taps. Most households with continuous supply continued to store water for drinking, resulting in re-contamination, which may reduce the benefits to water quality of converting to continuous supply. Copyright © 2013 Elsevier Ltd. All rights reserved.

Quantum key based burst confidentiality in optical burst switched networks.

Science.gov (United States)

Balamurugan, A M; Sivasubramanian, A

2014-01-01

The optical burst switching (OBS) is an emergent result to the technology concern that could achieve a feasible network in future. They are endowed with the ability to meet the bandwidth requirement of those applications that require intensive bandwidth. There are more domains opening up in the OBS that evidently shows their advantages and their capability to face the future network traffic. However, the concept of OBS is still far from perfection facing issues in case of security threat. The transfer of optical switching paradigm to optical burst switching faces serious downfall in the fields of burst aggregation, routing, authentication, dispute resolution, and quality of service (QoS). This paper deals with employing RC4 (stream cipher) to encrypt and decrypt bursts thereby ensuring the confidentiality of the burst. Although the use of AES algorithm has already been proposed for the same issue, by contrasting the two algorithms under the parameters of burst encryption and decryption time, end-to-end delay, it was found that RC4 provided better results. This paper looks to provide a better solution for the confidentiality of the burst in OBS networks.

Quantum Key Based Burst Confidentiality in Optical Burst Switched Networks

Directory of Open Access Journals (Sweden)

A. M. Balamurugan

2014-01-01

Full Text Available The optical burst switching (OBS is an emergent result to the technology concern that could achieve a feasible network in future. They are endowed with the ability to meet the bandwidth requirement of those applications that require intensive bandwidth. There are more domains opening up in the OBS that evidently shows their advantages and their capability to face the future network traffic. However, the concept of OBS is still far from perfection facing issues in case of security threat. The transfer of optical switching paradigm to optical burst switching faces serious downfall in the fields of burst aggregation, routing, authentication, dispute resolution, and quality of service (QoS. This paper deals with employing RC4 (stream cipher to encrypt and decrypt bursts thereby ensuring the confidentiality of the burst. Although the use of AES algorithm has already been proposed for the same issue, by contrasting the two algorithms under the parameters of burst encryption and decryption time, end-to-end delay, it was found that RC4 provided better results. This paper looks to provide a better solution for the confidentiality of the burst in OBS networks.

Burst suppression probability algorithms: state-space methods for tracking EEG burst suppression

Science.gov (United States)

Chemali, Jessica; Ching, ShiNung; Purdon, Patrick L.; Solt, Ken; Brown, Emery N.

2013-10-01

Objective. Burst suppression is an electroencephalogram pattern in which bursts of electrical activity alternate with an isoelectric state. This pattern is commonly seen in states of severely reduced brain activity such as profound general anesthesia, anoxic brain injuries, hypothermia and certain developmental disorders. Devising accurate, reliable ways to quantify burst suppression is an important clinical and research problem. Although thresholding and segmentation algorithms readily identify burst suppression periods, analysis algorithms require long intervals of data to characterize burst suppression at a given time and provide no framework for statistical inference. Approach. We introduce the concept of the burst suppression probability (BSP) to define the brain's instantaneous propensity of being in the suppressed state. To conduct dynamic analyses of burst suppression we propose a state-space model in which the observation process is a binomial model and the state equation is a Gaussian random walk. We estimate the model using an approximate expectation maximization algorithm and illustrate its application in the analysis of rodent burst suppression recordings under general anesthesia and a patient during induction of controlled hypothermia. Main result. The BSP algorithms track burst suppression on a second-to-second time scale, and make possible formal statistical comparisons of burst suppression at different times. Significance. The state-space approach suggests a principled and informative way to analyze burst suppression that can be used to monitor, and eventually to control, the brain states of patients in the operating room and in the intensive care unit.

THE FERMI-GBM X-RAY BURST MONITOR: THERMONUCLEAR BURSTS FROM 4U 0614+09

International Nuclear Information System (INIS)

Linares, M.; Chakrabarty, D.; Connaughton, V.; Bhat, P. N.; Briggs, M. S.; Preece, R.; Jenke, P.; Kouveliotou, C.; Wilson-Hodge, C. A.; Van der Horst, A. J.; Camero-Arranz, A.; Finger, M.; Paciesas, W. S.; Beklen, E.; Von Kienlin, A.

2012-01-01

Thermonuclear bursts from slowly accreting neutron stars (NSs) have proven difficult to detect, yet they are potential probes of the thermal properties of the NS interior. During the first year of a systematic all-sky search for X-ray bursts using the Gamma-ray Burst Monitor aboard the Fermi Gamma-ray Space Telescope we have detected 15 thermonuclear bursts from the NS low-mass X-ray binary 4U 0614+09 when it was accreting at nearly 1% of the Eddington limit. We measured an average burst recurrence time of 12 ± 3 days (68% confidence interval) between 2010 March and 2011 March, classified all bursts as normal duration bursts and placed a lower limit on the recurrence time of long/intermediate bursts of 62 days (95% confidence level). We discuss how observations of thermonuclear bursts in the hard X-ray band compare to pointed soft X-ray observations and quantify such bandpass effects on measurements of burst radiated energy and duration. We put our results for 4U 0614+09 in the context of other bursters and briefly discuss the constraints on ignition models. Interestingly, we find that the burst energies in 4U 0614+09 are on average between those of normal duration bursts and those measured in long/intermediate bursts. Such a continuous distribution in burst energy provides a new observational link between normal and long/intermediate bursts. We suggest that the apparent bimodal distribution that defined normal and long/intermediate duration bursts during the last decade could be due to an observational bias toward detecting only the longest and most energetic bursts from slowly accreting NSs.

Fuzzy-Based Adaptive Hybrid Burst Assembly Technique for Optical Burst Switched Networks

Directory of Open Access Journals (Sweden)

Abubakar Muhammad Umaru

2014-01-01

Full Text Available The optical burst switching (OBS paradigm is perceived as an intermediate switching technology for future all-optical networks. Burst assembly that is the first process in OBS is the focus of this paper. In this paper, an intelligent hybrid burst assembly algorithm that is based on fuzzy logic is proposed. The new algorithm is evaluated against the traditional hybrid burst assembly algorithm and the fuzzy adaptive threshold (FAT burst assembly algorithm via simulation. Simulation results show that the proposed algorithm outperforms the hybrid and the FAT algorithms in terms of burst end-to-end delay, packet end-to-end delay, and packet loss ratio.

Broadband Spectral Investigations of Magnetar Bursts

Science.gov (United States)

Kırmızıbayrak, Demet; Şaşmaz Muş, Sinem; Kaneko, Yuki; Göğüş, Ersin

2017-09-01

We present our broadband (2-250 keV) time-averaged spectral analysis of 388 bursts from SGR J1550-5418, SGR 1900+14, and SGR 1806-20 detected with the Rossi X-ray Timing Explorer (RXTE) here and as a database in a companion web-catalog. We find that two blackbody functions (BB+BB), the sum of two modified blackbody functions (LB+LB), the sum of a blackbody function and a power-law function (BB+PO), and a power law with a high-energy exponential cutoff (COMPT) all provide acceptable fits at similar levels. We performed numerical simulations to constrain the best fitting model for each burst spectrum and found that 67.6% of burst spectra with well-constrained parameters are better described by the Comptonized model. We also found that 64.7% of these burst spectra are better described with the LB+LB model, which is employed in the spectral analysis of a soft gamma repeater (SGR) for the first time here, than with the BB+BB and BB+PO models. We found a significant positive lower bound trend on photon index, suggesting a decreasing upper bound on hardness, with respect to total flux and fluence. We compare this result with bursts observed from SGR and AXP (anomalous X-ray pulsar) sources and suggest that the relationship is a distinctive characteristic between the two. We confirm a significant anticorrelation between burst emission area and blackbody temperature, and find that it varies between the hot and cool blackbody temperatures differently than previously discussed. We expand on the interpretation of our results in the framework of a strongly magnetized neutron star.

Broadband Spectral Investigations of Magnetar Bursts

Energy Technology Data Exchange (ETDEWEB)

Kırmızıbayrak, Demet; Şaşmaz Muş, Sinem; Kaneko, Yuki; Göğüş, Ersin, E-mail: demetk@sabanciuniv.edu [Faculty of Engineering and Natural Sciences, Sabancı University, Orhanlı Tuzla, Istanbul 34956 (Turkey)

2017-09-01

We present our broadband (2–250 keV) time-averaged spectral analysis of 388 bursts from SGR J1550−5418, SGR 1900+14, and SGR 1806−20 detected with the Rossi X-ray Timing Explorer ( RXTE ) here and as a database in a companion web-catalog. We find that two blackbody functions (BB+BB), the sum of two modified blackbody functions (LB+LB), the sum of a blackbody function and a power-law function (BB+PO), and a power law with a high-energy exponential cutoff (COMPT) all provide acceptable fits at similar levels. We performed numerical simulations to constrain the best fitting model for each burst spectrum and found that 67.6% of burst spectra with well-constrained parameters are better described by the Comptonized model. We also found that 64.7% of these burst spectra are better described with the LB+LB model, which is employed in the spectral analysis of a soft gamma repeater (SGR) for the first time here, than with the BB+BB and BB+PO models. We found a significant positive lower bound trend on photon index, suggesting a decreasing upper bound on hardness, with respect to total flux and fluence. We compare this result with bursts observed from SGR and AXP (anomalous X-ray pulsar) sources and suggest that the relationship is a distinctive characteristic between the two. We confirm a significant anticorrelation between burst emission area and blackbody temperature, and find that it varies between the hot and cool blackbody temperatures differently than previously discussed. We expand on the interpretation of our results in the framework of a strongly magnetized neutron star.

Radon and rock bursts in deep mines

International Nuclear Information System (INIS)

Bulashevich, Yu.P.; Utkin, V.I.; Yurkov, A.K.; Nikolaev, V.V.

1996-01-01

Variation fields of radon concentration in time to ascertain stress-strain state of the North Ural bauxite mines have been studied. It is shown that dynamic changes in the stress-strain state of the rocks prior to the rock burst bring about variations in radon concentration in the observation wells. Depending on mutual positioning of the observation points and the rock burst epicenter, the above-mentioned variations differ in principle, reduction of radon concentration in the near zone and its increase in the far zone are observed [ru

Inhibitory Effect of Nasal Intermittent Positive Pressure Ventilation on Gastroesophageal Reflux.

Directory of Open Access Journals (Sweden)

Danny Cantin

Full Text Available Non-invasive intermittent positive pressure ventilation can lead to esophageal insufflations and in turn to gastric distension. The fact that the latter induces transient relaxation of the lower esophageal sphincter implies that it may increase gastroesophageal refluxes. We previously reported that nasal Pressure Support Ventilation (nPSV, contrary to nasal Neurally-Adjusted Ventilatory Assist (nNAVA, triggers active inspiratory laryngeal closure. This suggests that esophageal insufflations are more frequent in nPSV than in nNAVA. The objectives of the present study were to test the hypotheses that: i gastroesophageal refluxes are increased during nPSV compared to both control condition and nNAVA; ii esophageal insufflations occur more frequently during nPSV than nNAVA. Polysomnographic recordings and esophageal multichannel intraluminal impedance pHmetry were performed in nine chronically instrumented newborn lambs to study gastroesophageal refluxes, esophageal insufflations, states of alertness, laryngeal closure and respiration. Recordings were repeated without sedation in control condition, nPSV (15/4 cmH2O and nNAVA (~ 15/4 cmH2O. The number of gastroesophageal refluxes recorded over six hours, expressed as median (interquartile range, decreased during both nPSV (1 (0, 3 and nNAVA [1 (0, 3] compared to control condition (5 (3, 10, (p < 0.05. Meanwhile, the esophageal insufflation index did not differ between nPSV (40 (11, 61 h-1 and nNAVA (10 (9, 56 h-1 (p = 0.8. In conclusion, nPSV and nNAVA similarly inhibit gastroesophageal refluxes in healthy newborn lambs at pressures that do not lead to gastric distension. In addition, the occurrence of esophageal insufflations is not significantly different between nPSV and nNAVA. The strong inhibitory effect of nIPPV on gastroesophageal refluxes appears identical to that reported with nasal continuous positive airway pressure.

Gamma Ray Burst Discoveries by the Swift Mission

Science.gov (United States)

Gehrels, Neil

2006-01-01

Gamma-ray bursts are among the most fascinating occurrences in the cosmos. They are thought to be the birth cries of black holes throughout the universe. The NASA swift mission is an innovative new multiwavelength observatory designed to determine the origin of bursts and use them to probe the early Universe. Swift is now in orbit since November 20, 2004 and all hardware is performing well. A new-technology wide-field gamma-ray camera is detecting a hundred bursts per year. sensitive narrow-field X-ray and uv/optical telescopes, built in collaboration with UK and Italian partners, are pointed at the burst location in 50-100 sec by an autonomously controlled "swift" spacecraft. For each burst, arcsec positions are determined and optical/UV/X-ray/gamma-ray spectrophotometry performed. Information is also rapidly sent to the ground to a team of more than 50 observers at telescopes around the world. The first year of findings from the mission will be presented. There has been a break-through in the longstanding mystery of short GRBs; they appear to be caused by merging neutron stars. High redshift bursts have been detected leading to a better understanding of star formation rates and distant galaxy environments. GRBs have been found with giant X-ray flares occurring in their afterglow.

Gamma Ray Burst Discoveries by the Swift Mission

Science.gov (United States)

Gehrels, Neil

2006-04-01

Gamma-ray bursts are among the most fascinating occurrences in the cosmos. They are thought to be the birth cries of black holes throughout the universe. The NASA Swift mission is an innovative new multiwavelength observatory designed to determine the origin of bursts and use them to probe the early Universe. Swift is now in orbit since November 20, 2004 and all hardware is performing well. A new-technology wide-field gamma-ray camera is detecting a hundred bursts per year. Sensitive narrow-field X-ray and UV/optical telescopes, built in collaboration with UK and Italian partners, are pointed at the burst location in 50-100 sec by an autonomously controlled ``swift'' spacecraft. For each burst, arcsec positions are determined and optical/UV/X-ray/gamma-ray spectrophotometry performed. Information is also rapidly sent to the ground to a team of more than 50 observers at telescopes around the world. The first year of findings from the mission will be presented. There has been a break-through in the long-standing mystery of short GRBs; they appear to be caused by merging neutron stars. High redshift bursts have been detected leading to a better understanding of star formation rates and distant galaxy environments. GRBs have been found with giant X-ray flares occurring in their afterglow.

Automatic burst detection for the EEG of the preterm infant.

Science.gov (United States)

Jennekens, Ward; Ruijs, Loes S; Lommen, Charlotte M L; Niemarkt, Hendrik J; Pasman, Jaco W; van Kranen-Mastenbroek, Vivianne H J M; Wijn, Pieter F F; van Pul, Carola; Andriessen, Peter

2011-10-01

To aid with prognosis and stratification of clinical treatment for preterm infants, a method for automated detection of bursts, interburst-intervals (IBIs) and continuous patterns in the electroencephalogram (EEG) is developed. Results are evaluated for preterm infants with normal neurological follow-up at 2 years. The detection algorithm (MATLAB®) for burst, IBI and continuous pattern is based on selection by amplitude, time span, number of channels and numbers of active electrodes. Annotations of two neurophysiologists were used to determine threshold values. The training set consisted of EEG recordings of four preterm infants with postmenstrual age (PMA, gestational age + postnatal age) of 29-34 weeks. Optimal threshold values were based on overall highest sensitivity. For evaluation, both observers verified detections in an independent dataset of four EEG recordings with comparable PMA. Algorithm performance was assessed by calculation of sensitivity and positive predictive value. The results of algorithm evaluation are as follows: sensitivity values of 90% ± 6%, 80% ± 9% and 97% ± 5% for burst, IBI and continuous patterns, respectively. Corresponding positive predictive values were 88% ± 8%, 96% ± 3% and 85% ± 15%, respectively. In conclusion, the algorithm showed high sensitivity and positive predictive values for bursts, IBIs and continuous patterns in preterm EEG. Computer-assisted analysis of EEG may allow objective and reproducible analysis for clinical treatment.

DO THE FERMI GAMMA-RAY BURST MONITOR AND SWIFT BURST ALERT TELESCOPE SEE THE SAME SHORT GAMMA-RAY BURSTS?

International Nuclear Information System (INIS)

Burns, Eric; Briggs, Michael S.; Connaughton, Valerie; Zhang, Bin-Bin; Lien, Amy; Goldstein, Adam; Pelassa, Veronique; Troja, Eleonora

2016-01-01

Compact binary system mergers are expected to generate gravitational radiation detectable by ground-based interferometers. A subset of these, the merger of a neutron star with another neutron star or a black hole, are also the most popular model for the production of short gamma-ray bursts (GRBs). The Swift Burst Alert Telescope (BAT) and the Fermi Gamma-ray Burst Monitor (GBM) trigger on short GRBs (SGRBs) at rates that reflect their relative sky exposures, with the BAT detecting 10 per year compared to about 45 for GBM. We examine the SGRB populations detected by Swift BAT and Fermi GBM. We find that the Swift BAT triggers on weaker SGRBs than Fermi GBM, providing they occur close to the center of the BAT field of view, and that the Fermi GBM SGRB detection threshold remains flatter across its field of view. Overall, these effects combine to give the instruments the same average sensitivity, and account for the SGRBs that trigger one instrument but not the other. We do not find any evidence that the BAT and GBM are detecting significantly different populations of SGRBs. Both instruments can detect untriggered SGRBs using ground searches seeded with time and position. The detection of SGRBs below the on-board triggering sensitivities of Swift BAT and Fermi GBM increases the possibility of detecting and localizing the electromagnetic counterparts of gravitational wave (GW) events seen by the new generation of GW detectors

DO THE FERMI GAMMA-RAY BURST MONITOR AND SWIFT BURST ALERT TELESCOPE SEE THE SAME SHORT GAMMA-RAY BURSTS?

Energy Technology Data Exchange (ETDEWEB)

Burns, Eric; Briggs, Michael S. [University of Alabama in Huntsville, 320 Sparkman Drive, Huntsville, AL 35805 (United States); Connaughton, Valerie [Universities Space Research Association, Science and Technology Institute, 320 Sparkman Drive, Huntsville, AL 35805 (United States); Zhang, Bin-Bin [Center for Space Plasma and Aeronomic Research (CSPAR), University of Alabama in Huntsville, Huntsville, AL 35899 (United States); Lien, Amy [Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Goldstein, Adam [NASA Postdoctoral Program, Space Science Office, VP62, NASA/Marshall Space Flight Center, Huntsville, AL 35812 (United States); Pelassa, Veronique [Smithsonian Astrophysical Observatory, P.O. Box 97, Amado, AZ 85645 (United States); Troja, Eleonora, E-mail: eb0016@uah.edu [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States)

2016-02-20

Compact binary system mergers are expected to generate gravitational radiation detectable by ground-based interferometers. A subset of these, the merger of a neutron star with another neutron star or a black hole, are also the most popular model for the production of short gamma-ray bursts (GRBs). The Swift Burst Alert Telescope (BAT) and the Fermi Gamma-ray Burst Monitor (GBM) trigger on short GRBs (SGRBs) at rates that reflect their relative sky exposures, with the BAT detecting 10 per year compared to about 45 for GBM. We examine the SGRB populations detected by Swift BAT and Fermi GBM. We find that the Swift BAT triggers on weaker SGRBs than Fermi GBM, providing they occur close to the center of the BAT field of view, and that the Fermi GBM SGRB detection threshold remains flatter across its field of view. Overall, these effects combine to give the instruments the same average sensitivity, and account for the SGRBs that trigger one instrument but not the other. We do not find any evidence that the BAT and GBM are detecting significantly different populations of SGRBs. Both instruments can detect untriggered SGRBs using ground searches seeded with time and position. The detection of SGRBs below the on-board triggering sensitivities of Swift BAT and Fermi GBM increases the possibility of detecting and localizing the electromagnetic counterparts of gravitational wave (GW) events seen by the new generation of GW detectors.

Swift-BAT: The First Year of Gamma-Ray Burst Detections

Science.gov (United States)

Krimm, Hans A.

2006-01-01

The Burst Alert Telescope (BAT) on the Swift has been detecting gamma-ray bursts (GRBs) since Dec. 17,2004 and automated burst alerts have been distributed since Feb. 14,2005. Since commissioning the BAT has triggered on more than 100 GRBs, nearly all of which have been followed up by the narrow-field instruments on Swift through automatic repointing, and by ground and other satellite telescopes after rapid notification. Within seconds of a trigger the BAT produces and relays to the ground a position good to three arc minutes and a four channel light curve. A full ten minutes of event data follows on subsequent ground station passes. The burst archive has allowed us to determine ensemble burst parameters such as fluence, peak flux and duration. An overview of the properties of BAT bursts and BAT'S performance as a burst monitor will be presented in this talk. BAT is a coded aperture imaging system with a wide (approx.2 sr) field of view consisting of a large coded mask located 1 m above a 5200 cm2 array of 32.768 CdZnTe detectors. All electronics and other hardware systems on the BAT have been operating well since commissioning and there is no sign of any degradation on orbit. The flight and ground software have proven similarly robust and allow the real time localization of all bursts and the rapid derivation of burst light curves, spectra and spectral fits on the ground.

Effects of Intermittent Fasting, Caloric Restriction, and Ramadan Intermittent Fasting on Cognitive Performance at Rest and During Exercise in Adults.

Science.gov (United States)

Cherif, Anissa; Roelands, Bart; Meeusen, Romain; Chamari, Karim

2016-01-01

The aim of this review was to highlight the potent effects of intermittent fasting on the cognitive performance of athletes at rest and during exercise. Exercise interacts with dietary factors and has a positive effect on brain functioning. Furthermore, physical activity and exercise can favorably influence brain plasticity. Mounting evidence indicates that exercise, in combination with diet, affects the management of energy metabolism and synaptic plasticity by affecting molecular mechanisms through brain-derived neurotrophic factor, an essential neurotrophin that acts at the interface of metabolism and plasticity. The literature has also shown that certain aspects of physical performance and mental health, such as coping and decision-making strategies, can be negatively affected by daylight fasting. However, there are several types of intermittent fasting. These include caloric restriction, which is distinct from fasting and allows subjects to drink water ad libitum while consuming a very low-calorie food intake. Another type is Ramadan intermittent fasting, which is a religious practice of Islam, where healthy adult Muslims do not eat or drink during daylight hours for 1 month. Other religious practices in Islam (Sunna) also encourage Muslims to practice intermittent fasting outside the month of Ramadan. Several cross-sectional and longitudinal studies have shown that intermittent fasting has crucial effects on physical and intellectual performance by affecting various aspects of bodily physiology and biochemistry that could be important for athletic success. Moreover, recent findings revealed that immunological variables are also involved in cognitive functioning and that intermittent fasting might impact the relationship between cytokine expression in the brain and cognitive deficits, including memory deficits.

An origin for short gamma-ray bursts unassociated with current star formation.

Science.gov (United States)

Barthelmy, S D; Chincarini, G; Burrows, D N; Gehrels, N; Covino, S; Moretti, A; Romano, P; O'Brien, P T; Sarazin, C L; Kouveliotou, C; Goad, M; Vaughan, S; Tagliaferri, G; Zhang, B; Antonelli, L A; Campana, S; Cummings, J R; D'Avanzo, P; Davies, M B; Giommi, P; Grupe, D; Kaneko, Y; Kennea, J A; King, A; Kobayashi, S; Melandri, A; Meszaros, P; Nousek, J A; Patel, S; Sakamoto, T; Wijers, R A M J

2005-12-15

Two short (gamma-ray bursts (GRBs) have recently been localized and fading afterglow counterparts detected. The combination of these two results left unclear the nature of the host galaxies of the bursts, because one was a star-forming dwarf, while the other was probably an elliptical galaxy. Here we report the X-ray localization of a short burst (GRB 050724) with unusual gamma-ray and X-ray properties. The X-ray afterglow lies off the centre of an elliptical galaxy at a redshift of z = 0.258 (ref. 5), coincident with the position determined by ground-based optical and radio observations. The low level of star formation typical for elliptical galaxies makes it unlikely that the burst originated in a supernova explosion. A supernova origin was also ruled out for GRB 050709 (refs 3, 31), even though that burst took place in a galaxy with current star formation. The isotropic energy for the short bursts is 2-3 orders of magnitude lower than that for the long bursts. Our results therefore suggest that an alternative source of bursts--the coalescence of binary systems of neutron stars or a neutron star-black hole pair--are the progenitors of short bursts.

The voice conveys specific emotions: evidence from vocal burst displays.

Science.gov (United States)

Simon-Thomas, Emiliana R; Keltner, Dacher J; Sauter, Disa; Sinicropi-Yao, Lara; Abramson, Anna

2009-12-01

Studies of emotion signaling inform claims about the taxonomic structure, evolutionary origins, and physiological correlates of emotions. Emotion vocalization research has tended to focus on a limited set of emotions: anger, disgust, fear, sadness, surprise, happiness, and for the voice, also tenderness. Here, we examine how well brief vocal bursts can communicate 22 different emotions: 9 negative (Study 1) and 13 positive (Study 2), and whether prototypical vocal bursts convey emotions more reliably than heterogeneous vocal bursts (Study 3). Results show that vocal bursts communicate emotions like anger, fear, and sadness, as well as seldom-studied states like awe, compassion, interest, and embarrassment. Ancillary analyses reveal family-wise patterns of vocal burst expression. Errors in classification were more common within emotion families (e.g., 'self-conscious,' 'pro-social') than between emotion families. The three studies reported highlight the voice as a rich modality for emotion display that can inform fundamental constructs about emotion.

QKD-Based Secured Burst Integrity Design for Optical Burst Switched Networks

Science.gov (United States)

Balamurugan, A. M.; Sivasubramanian, A.; Parvathavarthini, B.

2016-03-01

The field of optical transmission has undergone numerous advancements and is still being researched mainly due to the fact that optical data transmission can be done at enormous speeds. It is quite evident that people prefer optical communication when it comes to large amount of data involving its transmission. The concept of switching in networks has matured enormously with several researches, architecture to implement and methods starting with Optical circuit switching to Optical Burst Switching. Optical burst switching is regarded as viable solution for switching bursts over networks but has several security vulnerabilities. However, this work exploited the security issues associated with Optical Burst Switching with respect to integrity of burst. This proposed Quantum Key based Secure Hash Algorithm (QKBSHA-512) with enhanced compression function design provides better avalanche effect over the conventional integrity algorithms.

Intermittent theta burst over M1 may increase peak power of a Wingate anaerobic test and prevent the reduction of voluntary activation measured with transcranial magnetic stimulation

Directory of Open Access Journals (Sweden)

Louis-Solal Giboin

2016-07-01

Full Text Available Despite the potential of repetitive transcranial magnetic stimulation (rTMS to improve performances in patients suffering from motor neuronal afflictions, its effect on motor performance enhancement in healthy subjects during a specific sport task is still unknown. We hypothesised that after an intermittent theta burst (iTBS treatment, performance during the Wingate Anaerobic Test (WAnT, will increase and supraspinal fatigue following the exercise will be lower in comparison to a control treatment.Ten subjects participated in two randomised experiments consisting of a WAnT 5 minutes after either an iTBS or a control treatment. We determined voluntary activation (VA of the right knee extensors with TMS (VATMS and with peripheral nerve stimulation (VAPNS of the femoral nerve, before and after the WAnT. T-tests were applied to the WAnT results and a 2 way within subject ANOVA was applied to VA results. The iTBS treatment increased the peak power and the maximum pedalling cadence and suppressed the reduction of VATMS following the WAnT compared to the control treatment. No behavioural changes related to fatigue (mean power and fatigue index were observed.These results indicate for the first time that iTBS could be used as a potential intervention to improve anaerobic performance in a sport specific task.

Reproducibility of Single-Pulse, Paired-Pulse, and Intermittent Theta-Burst TMS Measures in Healthy Aging, Type-2 Diabetes, and Alzheimer’s Disease

Directory of Open Access Journals (Sweden)

Peter J. Fried

2017-08-01

Full Text Available Background: Transcranial magnetic stimulation (TMS can be used to assess neurophysiology and the mechanisms of cortical brain plasticity in humans in vivo. As the use of these measures in specific populations (e.g., Alzheimer’s disease; AD increases, it is critical to understand their reproducibility (i.e., test–retest reliability in the populations of interest.Objective: Reproducibility of TMS measures was evaluated in older adults, including healthy, AD, and Type-2 diabetes mellitus (T2DM groups.Methods: Participants received two identical neurophysiological assessments within a year including motor thresholds, baseline motor evoked potentials (MEPs, short- and long-interval intracortical inhibition (SICI, LICI and intracortical facilitation (ICF, and MEP changes following intermittent theta-burst stimulation (iTBS. Cronbach’s α coefficients were calculated to assess reproducibility. Multiple linear regression analyses were used to investigate factors related to intraindividual variability.Results: Reproducibility was highest for motor thresholds, followed by baseline MEPs, SICI and LICI, and was lowest for ICF and iTBS aftereffects. The AD group tended to show higher reproducibility than T2DM or controls. Intraindividual variability of baseline MEPs was related to age and variability of RMT, while the intraindividual variability in post-iTBS measures was related to baseline MEP variability, intervisit duration, and Brain-derived neurotrophic factor (BDNF polymorphism.Conclusion: Increased reproducibility in AD may reflect pathophysiological declines in the efficacy of neuroplastic mechanisms. Reproducibility of iTBS aftereffects can be improved by keeping baseline MEPs consistent, controlling for BDNF genotype, and waiting at least a week between visits.Significance: These findings provide the first direct assessment of reproducibility of TMS measures in older clinical populations. Reproducibility coefficients may be used to adjust

The genesis of period-adding bursting without bursting-chaos in the Chay model

International Nuclear Information System (INIS)

Yang Zhuoqin; Lu Qishao; Li Li

2006-01-01

According to the period-adding firing patterns without chaos observed in neuronal experiments, the genesis of the period-adding 'fold/homoclinic' bursting sequence without bursting-chaos is explored by numerical simulation, fast/slow dynamics and bifurcation analysis of limit cycle in the neuronal Chay model. It is found that each periodic bursting, from period-1 to 7, is separately generated by the corresponding periodic spiking pattern through two period-doubling bifurcations, except for the period-1 bursting occurring via a Hopf bifurcation. Consequently, it can be revealed that this period-adding bursting bifurcation without chaos has a compound bifurcation structure with transitions from spiking to bursting, which is closely related to period-doubling bifurcations of periodic spiking in essence

Theta Burst Stimulation Enhances Connectivity of the Dorsal Attention Network in Young Healthy Subjects: An Exploratory Study

Directory of Open Access Journals (Sweden)

Lubomira Anderkova

2018-01-01

Full Text Available We examined effects of theta burst stimulation (TBS applied over two distinct cortical areas (the right inferior frontal gyrus and the left superior parietal lobule on the Stroop task performance in 20 young healthy subjects. Neural underpinnings of the behavioral effect were tested using fMRI. A single session of intermittent TBS of the left superior parietal lobule induced certain cognitive speed enhancement and significantly increased resting-state connectivity of the dorsal attention network. This is an exploratory study that prompts further research with multiple-session TBS in subjects with cognitive impairment.

The genesis of period-adding bursting without bursting-chaos in the Chay model

International Nuclear Information System (INIS)

Yang Zhuoqin; Lu Qishao; Li Li

2006-01-01

According to the period-adding firing patterns without chaos observed in neuronal experiments, the genesis of the period-adding 'fold/homoclinic' bursting sequence without bursting-chaos is explored by numerical simulation, fast/slow dynamics and bifurcation analysis of limit cycle in the neuronal Chay model. It is found that each periodic bursting, from period-1 to period-7, is separately generated by the corresponding periodic spiking pattern through two period-doubling bifurcations, except for the period-1 bursting occurring via a Hopf bifurcation. Consequently, it can be revealed that this period-adding bursting bifurcation without chaos has a compound bifurcation structure with transitions from spiking to bursting, which is closely related to period-doubling bifurcations of periodic spiking in essence

INVESTIGATION OF PRIMORDIAL BLACK HOLE BURSTS USING INTERPLANETARY NETWORK GAMMA-RAY BURSTS

Energy Technology Data Exchange (ETDEWEB)

Ukwatta, T. N. [Director' s Postdoctoral Fellow, Space and Remote Sensing (ISR-2), Los Alamos National Laboratory, Los Alamos, NM 87545 (United States); Hurley, K. [University of California, Berkeley, Space Sciences Laboratory, 7 Gauss Way, Berkeley, CA 94720-7450 (United States); MacGibbon, J. H. [Department of Physics, University of North Florida, Jacksonville, FL 32224 (United States); Svinkin, D. S.; Aptekar, R. L.; Golenetskii, S. V.; Frederiks, D. D.; Pal' shin, V. D. [Ioffe Physical Technical Institute, St. Petersburg, 194021 (Russian Federation); Goldsten, J. [Applied Physics Laboratory, Johns Hopkins University, Laurel, MD 20723 (United States); Boynton, W. [Department of Planetary Sciences, University of Arizona, Tucson, AZ 85721 (United States); Kozyrev, A. S. [Space Research Institute, 84/32, Profsoyuznaya, Moscow 117997 (Russian Federation); Rau, A.; Kienlin, A. von; Zhang, X. [Max-Planck-Institut für extraterrestrische Physik, Giessenbachstrasse, Postfach 1312, Garching, D-85748 (Germany); Connaughton, V. [University of Alabama in Huntsville, NSSTC, 320 Sparkman Drive, Huntsville, AL 35805 (United States); Yamaoka, K. [Department of Physics and Mathematics, Aoyama Gakuin University, 5-10-1 Fuchinobe, Sagamihara, Kanagawa 229-8558 (Japan); Ohno, M. [Department of Physics, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima, Hiroshima 739-8526 (Japan); Ohmori, N. [Department of Applied Physics, University of Miyazaki, 1-1 Gakuen kibanadai-nishi, Miyazaki-shi, Miyazaki 889-2192 (Japan); Feroci, M. [INAF/IAPS-Roma, via Fosso del Cavaliere 100, I-00133, Roma (Italy); Frontera, F., E-mail: tilan@lanl.gov [Department of Physics and Earth Science, University of Ferrara, via Saragat 1, I-44122 Ferrara (Italy); and others

2016-07-20

The detection of a gamma-ray burst (GRB) in the solar neighborhood would have very important implications for GRB phenomenology. The leading theories for cosmological GRBs would not be able to explain such events. The final bursts of evaporating primordial black holes (PBHs), however, would be a natural explanation for local GRBs. We present a novel technique that can constrain the distance to GRBs using detections from widely separated, non-imaging spacecraft. This method can determine the actual distance to the burst if it is local. We applied this method to constrain distances to a sample of 36 short-duration GRBs detected by the Interplanetary Network (IPN) that show observational properties that are expected from PBH evaporations. These bursts have minimum possible distances in the 10{sup 13}–10{sup 18} cm (7–10{sup 5} au) range, which are consistent with the expected PBH energetics and with a possible origin in the solar neighborhood, although none of the bursts can be unambiguously demonstrated to be local. Assuming that these bursts are real PBH events, we estimate lower limits on the PBH burst evaporation rate in the solar neighborhood.

Four dimensional chaos and intermittency in a mesoscopic model of the electroencephalogram.

Science.gov (United States)

Dafilis, Mathew P; Frascoli, Federico; Cadusch, Peter J; Liley, David T J

2013-06-01

The occurrence of so-called four dimensional chaos in dynamical systems represented by coupled, nonlinear, ordinary differential equations is rarely reported in the literature. In this paper, we present evidence that Liley's mesoscopic theory of the electroencephalogram (EEG), which has been used to describe brain activity in a variety of clinically relevant contexts, possesses a chaotic attractor with a Kaplan-Yorke dimension significantly larger than three. This accounts for simple, high order chaos for a physiologically admissible parameter set. Whilst the Lyapunov spectrum of the attractor has only one positive exponent, the contracting dimensions are such that the integer part of the Kaplan-Yorke dimension is three, thus giving rise to four dimensional chaos. A one-parameter bifurcation analysis with respect to the parameter corresponding to extracortical input is conducted, with results indicating that the origin of chaos is due to an inverse period doubling cascade. Hence, in the vicinity of the high order, strange attractor, the model is shown to display intermittent behavior, with random alternations between oscillatory and chaotic regimes. This phenomenon represents a possible dynamical justification of some of the typical features of clinically established EEG traces, which can arise in the case of burst suppression in anesthesia and epileptic encephalopathies in early infancy.

Burst Detection and Localization using Discrete Wavelet Transform and Cross-Correlation

Directory of Open Access Journals (Sweden)

Eduardo Trutié-Carrero

2018-03-01

Full Text Available Burst in water distribution systems causes great loss of this natural resource, interrupts the water supply, damages the streets, builds and increases the transmission of infectious diseases. In this paper we propose a new algorithm that allows the detection and automatic localization of burst in water distribution systems. As for detection, the novelty is to use the wavelet correlation criterion to compute the statistical decision and compare it with a detection threshold. The novelty in the localization is to use the statistical operator cross-correlation. The algorithm was implemented in Octave and was validated with 32 signals acquired in the laboratory in a 26.7 m long steel pipe. In 16 signals burst were triggered which were detected under a false positive probability of 2 %. No false positives were present on the 16 signals where only noise was present.

Bursting star formation and the overabundance of Wolf-Rayet stars

International Nuclear Information System (INIS)

Bodigfee, G.; Deloore, C.

1985-01-01

The ratio of the number of WR-stars to their OB progenitors appears to be significantly higher in some extragalactic systems than in our Galaxy. This overabundance of Wolf-Rayet-stars can be explained as a consequence of a recent burst of star formation. It is suggested that this burst is the manifestation of a long period nonlinear oscillation in the star formation process, produced by positive feedback effects between young stars and the interstellar medium. Star burst galaxies with large numbers of WR-stars must generate gamma fluxes but due to the distance, all of them are beyond the reach of present-day detectors, except probably 30 Dor

Gamma Ray Bursts - Observations

Science.gov (United States)

Gehrels, N.; Cannizzo, J. K.

2010-01-01

We are in an exciting period of discovery for gamma-ray bursts. The Swift observatory is detecting 100 bursts per year, providing arcsecond localizations and sensitive observations of the prompt and afterglow emission. The Fermi observatory is observing 250 bursts per year with its medium-energy GRB instrument and about 10 bursts per year with its high-energy LAT instrument. In addition, rapid-response telescopes on the ground are providing new capabilities to study optical emission during the prompt phase and spectral signatures of the host galaxies. The combined data set is enabling great advances in our understanding of GRBs including afterglow physics, short burst origin, and high energy emission.

Intermittent versus continuous exercise training in chronic heart failure: a meta-analysis.

Science.gov (United States)

Smart, Neil A; Dieberg, Gudrun; Giallauria, Francesco

2013-06-20

We conducted a meta-analysis of randomized, controlled trials of combined strength and intermittent aerobic training, intermittent aerobic training only and continuous exercise training in heart failure patients. A systematic search was conducted of Medline (Ovid) (1950-September 2011), Embase.com (1974-September 2011), Cochrane Central Register of Controlled Trials and CINAHL (1981-September 19 2011). The search strategy included a mix of MeSH and free text terms for the key concepts heart failure, exercise training, interval training and intermittent exercise training. The included studies contained an aggregate of 446 patients, 212 completed intermittent exercise training, 66 only continuous exercise training, 59 completed combined intermittent and strength training and 109 sedentary controls. Weighted mean difference (MD) in Peak VO2 was 1.04mlkg(-1)min(-1) and (95% C.I.) was 0.42-1.66 (p=0.0009) in intermittent versus continuous exercise training respectively. Weighted mean difference in Peak VO2 was -1.10mlkg(-1)min(-1) (95% C.I.) was -1.83-0.37 p=0.003 for intermittent only versus intermittent and strength (combined) training respectively. In studies reporting VE/VCO2 for intermittent versus control groups, MD was -1.50 [(95% C.I. -2.64, -0.37), p=0.01] and for intermittent versus continuous exercise training MD was -1.35 [(95% C.I. -2.15, -0.55), p=0.001]. Change in peak VO2 was positively correlated with weekly exercise energy expenditure for intermittent exercise groups (r=0.48, p=0.05). Combined strength and intermittent exercise appears superior for peak VO2 changes when compared to intermittent exercise of similar exercise energy expenditure. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

The origin of cosmic gamma-ray bursts

International Nuclear Information System (INIS)

Van den Bergh, S.

1983-01-01

The positions of 46 γ-ray burst sources on the sky are used to show that the majority of these objects either originate in very distant regions with redshifts > or approx. 30 000 km s -1 or within < or approx. 0.5β of the Sun; where β is the scale-height of the parent population perpendicular to the galactic disc. An origin of the majority of γ-ray bursts in the more distant parts of the galactic disc, the galactic nuclear bulge, the Virgo supercluster, in galaxies with msub(pg) < 18 and rich in Abell clusters of distance classes 0 to 4 is excluded by the data. (orig.)

Heterogeneity in Short Gamma-Ray Bursts

Science.gov (United States)

Norris, Jay P.; Gehrels Neil; Scargle, Jeffrey D.

2011-01-01

We analyze the Swift/BAT sample of short gamma-ray bursts, using an objective Bayesian Block procedure to extract temporal descriptors of the bursts' initial pulse complexes (IPCs). The sample comprises 12 and 41 bursts with and without extended emission (EE) components, respectively. IPCs of non-EE bursts are dominated by single pulse structures, while EE bursts tend to have two or more pulse structures. The medians of characteristic timescales - durations, pulse structure widths, and peak intervals - for EE bursts are factors of approx 2-3 longer than for non-EE bursts. A trend previously reported by Hakkila and colleagues unifying long and short bursts - the anti-correlation of pulse intensity and width - continues in the two short burst groups, with non-EE bursts extending to more intense, narrower pulses. In addition we find that preceding and succeeding pulse intensities are anti-correlated with pulse interval. We also examine the short burst X-ray afterglows as observed by the Swift/XRT. The median flux of the initial XRT detections for EE bursts (approx 6 X 10(exp -10) erg / sq cm/ s) is approx > 20 x brighter than for non-EE bursts, and the median X-ray afterglow duration for EE bursts (approx 60,000 s) is approx 30 x longer than for non-EE bursts. The tendency for EE bursts toward longer prompt-emission timescales and higher initial X-ray afterglow fluxes implies larger energy injections powering the afterglows. The longer-lasting X-ray afterglows of EE bursts may suggest that a significant fraction explode into more dense environments than non-EE bursts, or that the sometimes-dominant EE component efficiently p()wers the afterglow. Combined, these results favor different progenitors for EE and non-EE short bursts.

HETEROGENEITY IN SHORT GAMMA-RAY BURSTS

International Nuclear Information System (INIS)

Norris, Jay P.; Gehrels, Neil; Scargle, Jeffrey D.

2011-01-01

We analyze the Swift/BAT sample of short gamma-ray bursts, using an objective Bayesian Block procedure to extract temporal descriptors of the bursts' initial pulse complexes (IPCs). The sample is comprised of 12 and 41 bursts with and without extended emission (EE) components, respectively. IPCs of non-EE bursts are dominated by single pulse structures, while EE bursts tend to have two or more pulse structures. The medians of characteristic timescales-durations, pulse structure widths, and peak intervals-for EE bursts are factors of ∼2-3 longer than for non-EE bursts. A trend previously reported by Hakkila and colleagues unifying long and short bursts-the anti-correlation of pulse intensity and width-continues in the two short burst groups, with non-EE bursts extending to more intense, narrower pulses. In addition, we find that preceding and succeeding pulse intensities are anti-correlated with pulse interval. We also examine the short burst X-ray afterglows as observed by the Swift/X-Ray Telescope (XRT). The median flux of the initial XRT detections for EE bursts (∼6x10 -10 erg cm -2 s -1 ) is ∼>20x brighter than for non-EE bursts, and the median X-ray afterglow duration for EE bursts (∼60,000 s) is ∼30x longer than for non-EE bursts. The tendency for EE bursts toward longer prompt-emission timescales and higher initial X-ray afterglow fluxes implies larger energy injections powering the afterglows. The longer-lasting X-ray afterglows of EE bursts may suggest that a significant fraction explode into denser environments than non-EE bursts, or that the sometimes-dominant EE component efficiently powers the afterglow. Combined, these results favor different progenitors for EE and non-EE short bursts.

Spectrum, time structure and direction of incidence of the August 16, 1976 gamma ray burst

International Nuclear Information System (INIS)

Sommer, H.; Mueller, D.; Horstman, H.; Bassani, L.

1977-01-01

Two major bursts of energetic photons have been recorded with a new balloon-borne instrument during the second transatlantic flight in 1976: One in coincidence with a type III solar radio burst on August 16 and a very energetic gamma ray burst of non-solar origin starting at 16:15.5 UT of August 16. Spectral information of the gamma ray burst has been obtained up to 2 MeV. A crude position of the burst source has been derived from data of a directional detector array after correcting for absorption and scattering in the earth's atmosphere. (author)

The bright gamma-ray burst of 2000 February 10: A case study of an optically dark gamma-ray burst

DEFF Research Database (Denmark)

Piro, L.; Frail, D.A.; Gorosabel, J.

2002-01-01

The gamma-ray burst GRB 000210 had the highest gamma-ray peak flux of any event localized by BeppoSAX as yet, but it did not have a detected optical afterglow, despite prompt and deep searches down to R-lim approximate to 23.5. It is therefore one of the events recently classified as dark GRBs......, whose origin is still unclear. Chandra observations allowed us to localize the X-ray afterglow of GRB 000210 to within approximate to1", and a radio transient was detected with the Very Large Array. The precise X-ray and radio positions allowed us to identify the likely host galaxy of this burst...

Intermittent Theta-Burst Stimulation of the Lateral Cerebellum Increases Functional Connectivity of the Default Network

Science.gov (United States)

Farzan, Faranak; Eldaief, Mark C.; Schmahmann, Jeremy D.; Pascual-Leone, Alvaro

2014-01-01

Cerebral cortical intrinsic connectivity networks share topographically arranged functional connectivity with the cerebellum. However, the contribution of cerebellar nodes to distributed network organization and function remains poorly understood. In humans, we applied theta-burst transcranial magnetic stimulation, guided by subject-specific connectivity, to regions of the cerebellum to evaluate the functional relevance of connections between cerebellar and cerebral cortical nodes in different networks. We demonstrate that changing activity in the human lateral cerebellar Crus I/II modulates the cerebral default mode network, whereas vermal lobule VII stimulation influences the cerebral dorsal attention system. These results provide novel insights into the distributed, but anatomically specific, modulatory impact of cerebellar effects on large-scale neural network function. PMID:25186750

BurstMem: A High-Performance Burst Buffer System for Scientific Applications

Energy Technology Data Exchange (ETDEWEB)

Wang, Teng [Auburn University, Auburn, Alabama; Oral, H Sarp [ORNL; Wang, Yandong [Auburn University, Auburn, Alabama; Settlemyer, Bradley W [ORNL; Atchley, Scott [ORNL; Yu, Weikuan [Auburn University, Auburn, Alabama

2014-01-01

The growth of computing power on large-scale sys- tems requires commensurate high-bandwidth I/O system. Many parallel file systems are designed to provide fast sustainable I/O in response to applications soaring requirements. To meet this need, a novel system is imperative to temporarily buffer the bursty I/O and gradually flush datasets to long-term parallel file systems. In this paper, we introduce the design of BurstMem, a high- performance burst buffer system. BurstMem provides a storage framework with efficient storage and communication manage- ment strategies. Our experiments demonstrate that BurstMem is able to speed up the I/O performance of scientific applications by up to 8.5 on leadership computer systems.

The voice conveys specific emotions: Evidence from vocal burst displays

OpenAIRE

Simon-Thomas, E.; Keltner, D.; Sauter, D.; Sinicropi-Yao, L.; Abramson, A.

2009-01-01

Studies of emotion signaling inform claims about the taxonomic structure, evolutionary origins, and physiological correlates of emotions. Emotion vocalization research has tended to focus on a limited set of emotions: anger, disgust, fear, sadness, surprise, happiness, and for the voice, also tenderness. Here, we examine how well brief vocal bursts can communicate 22 different emotions: 9 negative (Study 1) and 13 positive (Study 2), and whether prototypical vocal bursts convey emotions more ...

The application of coronal scattering measurements to solar radio bursts

International Nuclear Information System (INIS)

Bradford, H.M.

1980-01-01

The interpretation of ground based observations of solar 'plasma frequency' radio bursts has been hampered in the past by an insufficient knowledge of coronal scattering by density inhomogeneities close to the Sun. Calculations based on measuurements of the angular broadening of natural radio sources, and Woo's 1975 measurement of the angular broadening of the telemetry carrier by Helios I near occultation (Woo, 1978), indicate that plasma frequency solar bursts should undergo considerable scattering, at least near the maximum of the sunspot cycle. The calculated displacements of the apparent positions of the bursts are about equal to the observed displacements which have been attributed to the bursts occurring in dense streamers. In order to obtain more scattering data close to the Sun, interferometer measurements of the angular broadening of spacecraft signals are planned, and the important contribution which could be made with large dishes is discussed. (Auth.)

Rock Burst Monitoring by Integrated Microseismic and Electromagnetic Radiation Methods

Science.gov (United States)

Li, Xuelong; Wang, Enyuan; Li, Zhonghui; Liu, Zhentang; Song, Dazhao; Qiu, Liming

2016-11-01

For this study, microseismic (MS) and electromagnetic radiation (EMR) monitoring systems were installed in a coal mine to monitor rock bursts. The MS system monitors coal or rock mass ruptures in the whole mine, whereas the EMR equipment monitors the coal or rock stress in a small area. By analysing the MS energy, number of MS events, and EMR intensity with respect to rock bursts, it has been shown that the energy and number of MS events present a "quiet period" 1-3 days before the rock burst. The data also show that the EMR intensity reaches a peak before the rock burst and this EMR intensity peak generally corresponds to the MS "quiet period". There is a positive correlation between stress and EMR intensity. Buckling failure of coal or rock depends on the rheological properties and occurs after the peak stress in the high-stress concentration areas in deep mines. The MS "quiet period" before the rock burst is caused by the heterogeneity of the coal and rock structures, the transfer of high stress into internal areas, locked patches, and self-organized criticality near the stress peak. This study increases our understanding of coal and rock instability in deep mines. Combining MS and EMR to monitor rock burst could improve prediction accuracy.

A search for optical bursts from the repeating fast radio burst FRB 121102

Science.gov (United States)

Hardy, L. K.; Dhillon, V. S.; Spitler, L. G.; Littlefair, S. P.; Ashley, R. P.; De Cia, A.; Green, M. J.; Jaroenjittichai, P.; Keane, E. F.; Kerry, P.; Kramer, M.; Malesani, D.; Marsh, T. R.; Parsons, S. G.; Possenti, A.; Rattanasoon, S.; Sahman, D. I.

2017-12-01

We present a search for optical bursts from the repeating fast radio burst FRB 121102 using simultaneous observations with the high-speed optical camera ULTRASPEC on the 2.4-m Thai National Telescope and radio observations with the 100-m Effelsberg Radio Telescope. A total of 13 radio bursts were detected, but we found no evidence for corresponding optical bursts in our 70.7-ms frames. The 5σ upper limit to the optical flux density during our observations is 0.33 mJy at 767 nm. This gives an upper limit for the optical burst fluence of 0.046 Jy ms, which constrains the broad-band spectral index of the burst emission to α ≤ -0.2. Two of the radio pulses are separated by just 34 ms, which may represent an upper limit on a possible underlying periodicity (a rotation period typical of pulsars), or these pulses may have come from a single emission window that is a small fraction of a possible period.

Cosmic gamma bursts

International Nuclear Information System (INIS)

Ehstulin, I.V.

1980-01-01

A brief consideration is being given to the history of cosmic gamma burst discovery and modern knowledge of their properties. The time dependence of gamma bursts is described and their possible sources are discussed

Detection circuit for gamma-ray burst

International Nuclear Information System (INIS)

Murakami, Hiroyuki; Yamagami, Takamasa; Mori, Kunishiro; Uchiyama, Sadayuki.

1982-01-01

A new gamma-ray burst detection system is described. The system was developed as an environmental monitor of an accelerator, and can be used as the burst detection system. The system detects the arrival time of burst. The difference between the arrival times detected at different places will give information on the burst source. The frequency of detecting false burst was estimated, and the detection limit under the estimated frequency of false burst was also calculated. Decision whether the signal is false or true burst was made by the statistical treatment. (Kato, T.)

Intermittent Explosive Disorder

Directory of Open Access Journals (Sweden)

Lut Tamam

2011-09-01

Full Text Available Intermittent explosive disorder is an impulse control disorder characterized by the occurrence of discrete episodes of failure to resist aggressive impulses that result in violent assault or destruction of property. Though the prevalence intermittent explosive disorder has been reported to be relatively rare in frontier studies on the field, it is now common opinion that intermittent explosive disorder is far more common than previously thought especially in clinical psychiatry settings. Etiological studies displayed the role of both psychosocial factors like childhood traumas and biological factors like dysfunctional neurotransmitter systems and genetics. In differential diagnosis of the disorder, disorders involving agression as a symptom such as alcohol and drug intoxication, antisocial and borderline personality disorders, personality changes due to general medical conditions and behavioral disorder should be considered. A combination of pharmacological and psychotherapeutic approaches are suggested in the treatment of the disorder. This article briefly reviews the historical background, diagnostic criteria, epidemiology, etiology and treatment of intermittent explosive disorder.

Gamma-ray burst models.

Science.gov (United States)

King, Andrew

2007-05-15

I consider various possibilities for making gamma-ray bursts, particularly from close binaries. In addition to the much-studied neutron star+neutron star and black hole+neutron star cases usually considered good candidates for short-duration bursts, there are also other possibilities. In particular, neutron star+massive white dwarf has several desirable features. These systems are likely to produce long-duration gamma-ray bursts (GRBs), in some cases definitely without an accompanying supernova, as observed recently. This class of burst would have a strong correlation with star formation and occur close to the host galaxy. However, rare members of the class need not be near star-forming regions and could have any type of host galaxy. Thus, a long-duration burst far from any star-forming region would also be a signature of this class. Estimates based on the existence of a known progenitor suggest that this type of GRB may be quite common, in agreement with the fact that the absence of a supernova can only be established in nearby bursts.

VERY HIGH ENERGY OBSERVATIONS OF GAMMA-RAY BURSTS WITH STACEE

International Nuclear Information System (INIS)

Jarvis, A.; Ong, R. A.; Ball, J.; Carson, J. E.; Zweerink, J.; Williams, D. A.; Aune, T.; Covault, C. E.; Driscoll, D. D.; Fortin, P.; Mukherjee, R.; Gingrich, D. M.; Hanna, D. S.; Kildea, J.; Lindner, T.; Mueller, C.; Ragan, K.

2010-01-01

Gamma-ray bursts (GRBs) are the most powerful explosions known in the universe. Sensitive measurements of the high-energy spectra of GRBs can place important constraints on the burst environments and radiation processes. Until recently, there were no observations during the first few minutes of GRB afterglows in the energy range between 30 GeV and ∼1 TeV. With the launch of the Swift GRB Explorer in late 2004, GRB alerts and localizations within seconds of the bursts became available. The Solar Tower Atmospheric Cherenkov Effect Experiment (STACEE) was a ground-based, gamma-ray telescope with an energy threshold of ∼150 GeV for sources at zenith. At the time of Swift's launch, STACEE was in a rare position to provide >150 GeV follow-up observations of GRBs as fast as three minutes after the burst alert. In addition, STACEE performed follow-up observations of several GRBs that were localized by the HETE-2 and INTEGRAL satellites. Between 2002 June and 2007 July, STACEE made follow-up observations of 23 GRBs. Upper limits are placed on the high-energy gamma-ray fluxes from 21 of these bursts.

Solar microwave bursts - A review

Science.gov (United States)

Kundu, M. R.; Vlahos, L.

1982-01-01

Observational and theoretical results on the physics of microwave bursts that occur in the solar atmosphere are reviewed. Special attention is given to the advances made in burst physics over the last few years with the great improvement in spatial and time resolution, especially with instruments like the NRAO three-element interferometer, the Westerbork Synthesis Radio Telescope, and more recently the Very Large Array. Observations made on the preflare build-up of an active region at centimeter wavelengths are reviewed. Three distinct phases in the evolution of cm bursts, namely the impulsive phase, the post-burst phase, and the gradual rise and fall, are discussed. Attention is also given to the flux density spectra of centimeter bursts. Descriptions are given of observations of fine structures with temporal resolution of 10-100 ms in the intensity profiles of cm-wavelength bursts. High spatial resolution observations are analyzed, with special reference to the one- and two-dimensional maps of cm burst sources.

Cyclotron resonant scattering in the spectra of gamma-ray bursts

International Nuclear Information System (INIS)

Lamb, D.Q.; Wang, J.C.L.; Loredo, T.J.; Wasserman, I.; Fenimore, E.E.

1989-01-01

Data on the GB880205 gamma-ray bursts are presented that have implications for the nature of gamma-ray burst sources. It is shown that cyclotron resonant scattering and Raman scattering account well for the positions, strengths, and shapes of the relative strengths of the first and second harmonics and their narrow widths. These results imply the existence of a superstrong (B of about 2 x 10 to the 12th G) magnetic field in the vicinity of the X-ray emission region of GB880205. Such a superstrong magnetic field points to a strongly magnetic neutron star as the origin of gamma-ray bursts, and to the fact that the gamma-ray sources belong to the Galaxy. 59 refs

Optical observations of Gamma-Ray Bursts

International Nuclear Information System (INIS)

Hjorth, J.; Pian, E.; Fynbo, J.P.U.

2004-01-01

We briefly review the status and recent progress in the field of optical observations of gamma-ray burst afterglows. We will focus on the fundamental observational evidence for the relationship between gamma-ray bursts and the final evolutionary phases of massive stars. In particular, we will address (i) gamma-ray burst host galaxies, (ii) optically dark gamma-ray burst afterglows, (iii) the gamma-ray burst-supernova connection, and (iv) the relation between X-ray flashes, gamma-ray bursts, and supernovae

Solar Radio Bursts and Space Weather

Science.gov (United States)

Gopalswamy, Natchimuthuk,

2012-01-01

Radio bursts from the Sun are produced by electron accelerated to relativistic energies by physical processes on the Sun such as solar flares and coronal mass ejections (CMEs). The radio bursts are thus good indicators of solar eruptions. Three types of nonthermal radio bursts are generally associated with CMEs. Type III bursts due to accelerated electrons propagating along open magnetic field lines. The electrons are thought to be accelerated at the reconnection region beneath the erupting CME, although there is another view that the electrons may be accelerated at the CME-driven shock. Type II bursts are due to electrons accelerated at the shock front. Type II bursts are also excellent indicators of solar energetic particle (SEP) events because the same shock is supposed accelerate electrons and ions. There is a hierarchical relationship between the wavelength range of type /I bursts and the CME kinetic energy. Finally, Type IV bursts are due to electrons trapped in moving or stationary structures. The low frequency stationary type IV bursts are observed occasionally in association with very fast CMEs. These bursts originate from flare loops behind the erupting CME and hence indicate tall loops. This paper presents a summary of radio bursts and their relation to CMEs and how they can be useful for space weather predictions.

Intermittent heating of buildings

Energy Technology Data Exchange (ETDEWEB)

Kohonen, K

1983-02-01

Conditions for intermittent heating of buildings are considered both theoretically and experimentally. Thermal behaviour of buildings adn rooms in intermittent heating is simulated by a program based on the convective heat balance equation and by simplified RC-models. The preheat times and the heating energy savings compared with continuous heating are presented for typical lightweight, mediumweight and heavyweight classroom and office modules. Formulaes for estimating the oversizing of the radiator network, the maximum heat output of heat exchangers in district heating and the efficiency of heating boilers in intermittent heating are presented. The preheat times and heating energy savings with different heating control systems are determined also experimentally in eight existing buildings. In addition some principles for the planning and application of intermittent heating systems are suggested.

Automatic recognition of coronal type II radio bursts: The ARBIS 2 method and first observations

Science.gov (United States)

Lobzin, Vasili; Cairns, Iver; Robinson, Peter; Steward, Graham; Patterson, Garth

Major space weather events such as solar flares and coronal mass ejections are usually accompa-nied by solar radio bursts, which can potentially be used for real-time space weather forecasts. Type II radio bursts are produced near the local plasma frequency and its harmonic by fast electrons accelerated by a shock wave moving through the corona and solar wind with a typi-cal speed of 1000 km s-1 . The coronal bursts have dynamic spectra with frequency gradually falling with time and durations of several minutes. We present a new method developed to de-tect type II coronal radio bursts automatically and describe its implementation in an extended Automated Radio Burst Identification System (ARBIS 2). Preliminary tests of the method with spectra obtained in 2002 show that the performance of the current implementation is quite high, ˜ 80%, while the probability of false positives is reasonably low, with one false positive per 100-200 hr for high solar activity and less than one false event per 10000 hr for low solar activity periods. The first automatically detected coronal type II radio bursts are also presented. ARBIS 2 is now operational with IPS Radio and Space Services, providing email alerts and event lists internationally.

Complex transitions between spike, burst or chaos synchronization states in coupled neurons with coexisting bursting patterns

International Nuclear Information System (INIS)

Gu Hua-Guang; Chen Sheng-Gen; Li Yu-Ye

2015-01-01

We investigated the synchronization dynamics of a coupled neuronal system composed of two identical Chay model neurons. The Chay model showed coexisting period-1 and period-2 bursting patterns as a parameter and initial values are varied. We simulated multiple periodic and chaotic bursting patterns with non-(NS), burst phase (BS), spike phase (SS), complete (CS), and lag synchronization states. When the coexisting behavior is near period-2 bursting, the transitions of synchronization states of the coupled system follows very complex transitions that begins with transitions between BS and SS, moves to transitions between CS and SS, and to CS. Most initial values lead to the CS state of period-2 bursting while only a few lead to the CS state of period-1 bursting. When the coexisting behavior is near period-1 bursting, the transitions begin with NS, move to transitions between SS and BS, to transitions between SS and CS, and then to CS. Most initial values lead to the CS state of period-1 bursting but a few lead to the CS state of period-2 bursting. The BS was identified as chaos synchronization. The patterns for NS and transitions between BS and SS are insensitive to initial values. The patterns for transitions between CS and SS and the CS state are sensitive to them. The number of spikes per burst of non-CS bursting increases with increasing coupling strength. These results not only reveal the initial value- and parameter-dependent synchronization transitions of coupled systems with coexisting behaviors, but also facilitate interpretation of various bursting patterns and synchronization transitions generated in the nervous system with weak coupling strength. (paper)

Gamma-ray burst spectra

International Nuclear Information System (INIS)

Teegarden, B.J.

1982-01-01

A review of recent results in gamma-ray burst spectroscopy is given. Particular attention is paid to the recent discovery of emission and absorption features in the burst spectra. These lines represent the strongest evidence to date that gamma-ray bursts originate on or near neutron stars. Line parameters give information on the temperature, magnetic field and possibly the gravitational potential of the neutron star. The behavior of the continuum spectrum is also discussed. A remarkably good fit to nearly all bursts is obtained with a thermal-bremsstrahlung-like continuum. Significant evolution is observed of both the continuum and line features within most events

Intermittent pneumatic compression of legs increases microcirculation in distant skeletal muscle.

Science.gov (United States)

Liu, K; Chen, L E; Seaber, A V; Johnson, G W; Urbaniak, J R

1999-01-01

Intermittent pneumatic compression has been established as a method of clinically preventing deep vein thrombosis, but the mechanism has not been documented. This study observed the effects of intermittent pneumatic compression of legs on the microcirculation of distant skeletal muscle. The cremaster muscles of 80 male rats were exposed, a specially designed intermittent pneumatic-compression device was applied to both legs for 60 minutes, and the microcirculation of the muscles was assessed by measurement of the vessel diameter in three categories (10-20, 21-40, and 41-70 microm) for 120 minutes. The results showed significant vasodilation in arterial and venous vessels during the application of intermittent pneumatic compression, which disappeared after termination of the compression. The vasodilation reached a maximum 30 minutes after initiation of the compression and could be completely blocked by an inhibitor of nitric oxide synthase, NG-monomethyl-L-arginine (10 micromol/min). A 120-minute infusion of NG-monomethyl-L-arginine, beginning coincident with 60 minutes of intermittent pneumatic compression, resulted in a significant decrease in arterial diameter that remained at almost the same level after termination of the compression. The magnitude of the decrease in diameter in the group treated with intermittent pneumatic compression and NG-monomethyl-L-arginine was comparable with that in the group treated with NG-monomethyl-L-arginine alone. The results imply that the production of nitric oxide is involved in the positive influence of intermittent pneumatic compression on circulation. It is postulated that the rapid increase in venous velocity induced by intermittent pneumatic compression produces strong shear stress on the vascular endothelium, which stimulates an increased release of nitric oxide and thereby causes systemic vasodilation.

Chronic intermittent hypoxia alters local respiratory circuit function at the level of the preBötzinger complex

Directory of Open Access Journals (Sweden)

Alfredo J Garcia

2016-02-01

Full Text Available Chronic intermittent hypoxia (CIH is a common state experienced in several breathing disorders, including obstructive sleep apnea (OSA and apneas of prematurity. Unraveling how CIH affects the CNS, and in turn how the CNS contributes to apneas is perhaps the most challenging task. The preBötzinger complex (preBötC is a pre-motor respiratory network critical for inspiratory rhythm generation. Here, we test the hypothesis that CIH increases irregular output from the isolated preBötC, which can be mitigated by antioxidant treatment. Electrophysiological recordings from brainstem slices revealed that CIH enhanced burst-to-burst irregularity in period and/or amplitude. Irregularities represented a change in individual fidelity among preBötC neurons, and changed transmission from preBötC to the hypoglossal motor nucleus (XIIn, which resulted in increased transmission failure to XIIn. CIH increased the degree of lipid peroxidation in the preBötC and treatment with the antioxidant, 5,10,15,20-Tetrakis (1-methylpyridinium-4-yl-21H,23H-porphyrin manganese(III pentachloride (MnTMPyP, reduced CIH-mediated irregularities on the network rhythm and improved transmission of preBötC to the XIIn. These findings suggest that CIH promotes a pro-oxidant state that destabilizes rhythmogenesis originating from the preBötC and changes the local rhythm generating circuit which in turn, can lead to intermittent transmission failure to the XIIn. We propose that these CIH-mediated effects represent a part of the central mechanism that may perpetuate apneas and respiratory instability, which are hallmark traits in several dysautonomic conditions.

Optimal intermittent search strategies: smelling the prey

International Nuclear Information System (INIS)

Revelli, J A; Wio, H S; Rojo, F; Budde, C E

2010-01-01

We study the kinetics of the search of a single fixed target by a searcher/walker that performs an intermittent random walk, characterized by different states of motion. In addition, we assume that the walker has the ability to detect the scent left by the prey/target in its surroundings. Our results, in agreement with intuition, indicate that the prey's survival probability could be strongly reduced (increased) if the predator is attracted (or repelled) by the trace left by the prey. We have also found that, for a positive trace (the predator is guided towards the prey), increasing the inhomogeneity's size reduces the prey's survival probability, while the optimal value of α (the parameter that regulates intermittency) ceases to exist. The agreement between theory and numerical simulations is excellent.

Optimal intermittent search strategies: smelling the prey

Energy Technology Data Exchange (ETDEWEB)

Revelli, J A; Wio, H S [Instituto de Fisica de Cantabria, Universidad de Cantabria and CSIC, E-39005 Santander (Spain); Rojo, F; Budde, C E [Fa.M.A.F., Universidad Nacional de Cordoba, Ciudad Universitaria, X5000HUA Cordoba (Argentina)

2010-05-14

We study the kinetics of the search of a single fixed target by a searcher/walker that performs an intermittent random walk, characterized by different states of motion. In addition, we assume that the walker has the ability to detect the scent left by the prey/target in its surroundings. Our results, in agreement with intuition, indicate that the prey's survival probability could be strongly reduced (increased) if the predator is attracted (or repelled) by the trace left by the prey. We have also found that, for a positive trace (the predator is guided towards the prey), increasing the inhomogeneity's size reduces the prey's survival probability, while the optimal value of {alpha} (the parameter that regulates intermittency) ceases to exist. The agreement between theory and numerical simulations is excellent.

Analysis of historic bursts and burst detection in water supply areas of different size

NARCIS (Netherlands)

Bakker, M.; Trietsch, E.A.; Vreeburg, J.H.G.; Rietveld, L.C.

2014-01-01

Pipe bursts in water distribution networks lead to water losses and a risk of damaging the urban environment. We studied hydraulic data and customer contact records of 44 real bursts for a better understanding of the phenomena. We found that most bursts were reported to the water company shortly

Water quality effects of intermittent water supply in Arraiján, Panama.

Science.gov (United States)

Erickson, John J; Smith, Charlotte D; Goodridge, Amador; Nelson, Kara L

2017-05-01

Intermittent drinking water supply is common in low- and middle-income countries throughout the world and can cause water quality to degrade in the distribution system. In this study, we characterized water quality in one study zone with continuous supply and three zones with intermittent supply in the drinking water distribution network in Arraiján, Panama. Low or zero pressures occurred in all zones, and negative pressures occurred in the continuous zone and two of the intermittent zones. Despite hydraulic conditions that created risks for backflow and contaminant intrusion, only four of 423 (0.9%) grab samples collected at random times were positive for total coliform bacteria and only one was positive for E. coli. Only nine of 496 (1.8%) samples had turbidity >1.0 NTU and all samples had ≥0.2 mg/L free chlorine residual. In contrast, water quality was often degraded during the first-flush period (when supply first returned after an outage). Still, routine and first-flush water quality under intermittent supply was much better in Arraiján than that reported in a previous study conducted in India. Better water quality in Arraiján could be due to better water quality leaving the treatment plant, shorter supply outages, higher supply pressures, a more consistent and higher chlorine residual, and fewer contaminant sources near pipes. The results illustrate that intermittent supply and its effects on water quality can vary greatly between and within distribution networks. The study also demonstrated that monitoring techniques designed specifically for intermittent supply, such as continuous pressure monitoring and sampling the first flush, can detect water quality threats and degradation that would not likely be detected with conventional monitoring. Copyright © 2017 Elsevier Ltd. All rights reserved.

Fermi/GAMMA-RAY BURST MONITOR OBSERVATIONS OF SGR J0501+4516 BURSTS

International Nuclear Information System (INIS)

Lin Lin; Zhang Shuangnan; Kouveliotou, Chryssa; Baring, Matthew G.; Van der Horst, Alexander J.; Finger, Mark H.; Guiriec, Sylvain; Preece, Robert; Chaplin, Vandiver; Bhat, Narayan; Woods, Peter M.; Goegues, Ersin; Kaneko, Yuki; Scargle, Jeffrey; Granot, Jonathan; Von Kienlin, Andreas; Watts, Anna L.; Wijers, Ralph A. M. J.; Gehrels, Neil; Harding, Alice

2011-01-01

We present our temporal and spectral analyses of 29 bursts from SGR J0501+4516, detected with the gamma-ray burst monitor on board the Fermi Gamma-ray Space Telescope during 13 days of the source's activation in 2008 (August 22- September 3). We find that the T 90 durations of the bursts can be fit with a log-normal distribution with a mean value of ∼123 ms. We also estimate for the first time event durations of soft gamma repeater (SGR) bursts in photon space (i.e., using their deconvolved spectra) and find that these are very similar to the T 90 values estimated in count space (following a log-normal distribution with a mean value of ∼124 ms). We fit the time-integrated spectra for each burst and the time-resolved spectra of the five brightest bursts with several models. We find that a single power law with an exponential cutoff model fits all 29 bursts well, while 18 of the events can also be fit with two blackbody functions. We expand on the physical interpretation of these two models and we compare their parameters and discuss their evolution. We show that the time-integrated and time-resolved spectra reveal that E peak decreases with energy flux (and fluence) to a minimum of ∼30 keV at F = 8.7 x 10 -6 erg cm -2 s -1 , increasing steadily afterward. Two more sources exhibit a similar trend: SGRs J1550-5418 and 1806-20. The isotropic luminosity, L iso , corresponding to these flux values is roughly similar for all sources (0.4-1.5 x 10 40 erg s -1 ).

PWR clad ballooning: The effect of circumferential clad temperature variations on the burst strain/burst temperature relationship

International Nuclear Information System (INIS)

Barlow, P.

1983-01-01

By experiment, it has been shown by other workers that there is a reduction in the creep ductility of Zircaloy 4 in the α+β phase transition region. Results from single rod burst tests also show a reduction in burst strain in the α+β phase region. In this report it is shown theoretically that for single rod burst tests in the presence of circumferential temperature gradients, the temperature dependence of the mean burst strain is not determined by temperature variations in creep ductility, but is governed by the temperature sensitivity of the creep strain rate, which is shown to be a maximum in the α+β phase transition region. To demonstrate this effect, the mean clad strain at burst was calculated for creep straining at different temperature levels in the α, α+β and β phase regions. Cross-pin temperature gradients were applied which produced strain variations around the clad which were greatest in the α+β phase region. The mean strain at burst was determined using a maximum local burst strain (i.e. a creep ductility) which is independent of temperature. By assuming cross-pin temperature gradients which are typical of those observed during burst tests, then the calculated mean burst strain/burst temperature relationship gave good agreement with experiment. The calculations also show that when circumferential temperature differences are present, the calculated mean strain at burst is not sensitive to variations in the magnitude of the assumed creep ductility. This reduces the importance of the assumed burst criterion in the calculations. Hence a temperature independent creep ductility (e.g. 100% local strain) is adequate as a burst criterion for calculations under PWR LOCA conditions. (author)

Does Twitter trigger bursts in signature collections?

Science.gov (United States)

Yamaguchi, Rui; Imoto, Seiya; Kami, Masahiro; Watanabe, Kenji; Miyano, Satoru; Yuji, Koichiro

2013-01-01

The quantification of social media impacts on societal and political events is a difficult undertaking. The Japanese Society of Oriental Medicine started a signature-collecting campaign to oppose a medical policy of the Government Revitalization Unit to exclude a traditional Japanese medicine, "Kampo," from the public insurance system. The signature count showed a series of aberrant bursts from November 26 to 29, 2009. In the same interval, the number of messages on Twitter including the keywords "Signature" and "Kampo," increased abruptly. Moreover, the number of messages on an Internet forum that discussed the policy and called for signatures showed a train of spikes. In order to estimate the contributions of social media, we developed a statistical model with state-space modeling framework that distinguishes the contributions of multiple social media in time-series of collected public opinions. We applied the model to the time-series of signature counts of the campaign and quantified contributions of two social media, i.e., Twitter and an Internet forum, by the estimation. We found that a considerable portion (78%) of the signatures was affected from either of the social media throughout the campaign and the Twitter effect (26%) was smaller than the Forum effect (52%) in total, although Twitter probably triggered the initial two bursts of signatures. Comparisons of the estimated profiles of the both effects suggested distinctions between the social media in terms of sustainable impact of messages or tweets. Twitter shows messages on various topics on a time-line; newer messages push out older ones. Twitter may diminish the impact of messages that are tweeted intermittently. The quantification of social media impacts is beneficial to better understand people's tendency and may promote developing strategies to engage public opinions effectively. Our proposed method is a promising tool to explore information hidden in social phenomena.

Does Twitter trigger bursts in signature collections?

Directory of Open Access Journals (Sweden)

Rui Yamaguchi

Full Text Available INTRODUCTION: The quantification of social media impacts on societal and political events is a difficult undertaking. The Japanese Society of Oriental Medicine started a signature-collecting campaign to oppose a medical policy of the Government Revitalization Unit to exclude a traditional Japanese medicine, "Kampo," from the public insurance system. The signature count showed a series of aberrant bursts from November 26 to 29, 2009. In the same interval, the number of messages on Twitter including the keywords "Signature" and "Kampo," increased abruptly. Moreover, the number of messages on an Internet forum that discussed the policy and called for signatures showed a train of spikes. METHODS AND FINDINGS: In order to estimate the contributions of social media, we developed a statistical model with state-space modeling framework that distinguishes the contributions of multiple social media in time-series of collected public opinions. We applied the model to the time-series of signature counts of the campaign and quantified contributions of two social media, i.e., Twitter and an Internet forum, by the estimation. We found that a considerable portion (78% of the signatures was affected from either of the social media throughout the campaign and the Twitter effect (26% was smaller than the Forum effect (52% in total, although Twitter probably triggered the initial two bursts of signatures. Comparisons of the estimated profiles of the both effects suggested distinctions between the social media in terms of sustainable impact of messages or tweets. Twitter shows messages on various topics on a time-line; newer messages push out older ones. Twitter may diminish the impact of messages that are tweeted intermittently. CONCLUSIONS: The quantification of social media impacts is beneficial to better understand people's tendency and may promote developing strategies to engage public opinions effectively. Our proposed method is a promising tool to explore

Multidimensional intermittency in hadronic collisions

International Nuclear Information System (INIS)

Pan, J.; Hwa, R.C.

1992-06-01

The study of intermittency in high-energy hadronic collisions by the Monte Carlo code ECCO is extended to 3-dimensional phase space. Strong intermittency is found in agreement with the data. Fluctuation in the impact parameter is responsible for the intermittency in lnp T , and the transverse-momentum conservation leads to negative intermittency slopes in the azimuthal angle φ. The Ochs-Wosiek plots are linear in all dimensions having universal slopes. An exponent ν = 1.448 emerges to characterize multiparticle production in pp collisions. The properties of G moments are also examined, and the fractal dimensions determined

PROPAGATION OF RELATIVISTIC, HYDRODYNAMIC, INTERMITTENT JETS IN A ROTATING, COLLAPSING GRB PROGENITOR STAR

Energy Technology Data Exchange (ETDEWEB)

Geng, Jin-Jun [School of Astronomy and Space Science, Nanjing University, Nanjing 210046 (China); Zhang, Bing [Department of Physics and Astronomy, University of Nevada Las Vegas, NV 89154 (United States); Kuiper, Rolf, E-mail: gengjinjun@gmail.com, E-mail: zhang@physics.unlv.edu [Institute of Astronomy and Astrophysics, University of Tübingen, Auf der Morgenstelle 10, D-72076 Tübingen (Germany)

2016-12-10

The prompt emission of gamma-ray bursts (GRBs) is characterized by rapid variabilities, which may be a direct reflection of the unsteady central engine. We perform a series of axisymmetric 2.5-dimensional simulations to study the propagation of relativistic, hydrodynamic, intermittent jets through the envelope of a GRB progenitor star. A realistic rapidly rotating star is incorporated as the background of jet propagation, and the star is allowed to collapse due to the gravity of the central black hole. By modeling the intermittent jets with constant-luminosity pulses with equal on and off durations, we investigate how the half period, T , affects the jet dynamics. For relatively small T values (e.g., 0.2 s), the jet breakout time t {sub bo} depends on the opening angle of the jet, with narrower jets more penetrating and reaching the surface at shorter times. For T  ≤ 1 s, the reverse shock (RS) crosses each pulse before the jet penetrates through the stellar envelope. As a result, after the breakout of the first group of pulses at t {sub bo}, several subsequent pulses vanish before penetrating the star, causing a quiescent gap. For larger half periods ( T = 2.0 and 4.0 s), all the pulses can successfully penetrate through the envelope, since each pulse can propagate through the star before the RS crosses the shell. Our results may interpret the existence of a weak precursor in some long GRBs, given that the GRB central engine injects intermittent pulses with a half period T  ≤ 1 s. The observational data seem to be consistent with such a possibility.

A non-inferiority, individually randomized trial of intermittent screening and treatment versus intermittent preventive treatment in the control of malaria in pregnancy

DEFF Research Database (Denmark)

Tagbor, Harry; Cairns, Matthew; Bojang, Kalifa

2015-01-01

BACKGROUND: The efficacy of intermittent preventive treatment for malaria with sulfadoxine-pyrimethamine (IPTp-SP) in pregnancy is threatened in parts of Africa by the emergence and spread of resistance to SP. Intermittent screening with a rapid diagnostic test (RDT) and treatment of positive women...... with malaria parasitemia between routine antenatal clinics (310 vs 182 episodes, rate difference: 49.4 per 1,000 pregnancies [95% CI 30.5, 68.3], but the number of hospital admissions for malaria was similar in the two groups. CONCLUSIONS: Despite low levels of resistance to SP in the study areas, ISTp......-AL performed as well as IPTp-SP. In the absence of an effective alternative medication to SP for IPTp, ISTp-AL is a potential alternative to IPTp in areas where SP resistance is high. It may also have a role in areas where malaria transmission is low and for the prevention of malaria in HIV positive women...

X-ray bursts: Observation versus theory

Science.gov (United States)

Lewin, W. H. G.

1981-01-01

Results of various observations of common type I X-ray bursts are discussed with respect to the theory of thermonuclear flashes in the surface layers of accreting neutron stars. Topics covered include burst profiles; irregular burst intervals; rise and decay times and the role of hydrogen; the accuracy of source distances; accuracy in radii determination; radius increase early in the burst; the super Eddington limit; temperatures at burst maximum; and the role of the magnetic field.

Estimating detection rates for the LIGO-Virgo search for gravitational-wave burst counterparts to gamma-ray bursts using inferred local GRB rates

International Nuclear Information System (INIS)

Leonor, I; Frey, R; Sutton, P J; Jones, G; Marka, S; Marka, Z

2009-01-01

One of the ongoing searches performed using the LIGO-Virgo network of gravitational-wave interferometers is the search for gravitational-wave burst (GWB) counterparts to gamma-ray bursts (GRBs). This type of analysis makes use of GRB time and position information from gamma-ray satellite detectors to trigger the GWB search, and the GWB detection rates possible for such an analysis thus strongly depend on the GRB detection efficiencies of the satellite detectors. Using local GRB rate densities inferred from observations which are found in the science literature, we calculate estimates of the GWB detection rates for different configurations of the LIGO-Virgo network for this type of analysis.

Secured Hash Based Burst Header Authentication Design for Optical Burst Switched Networks

Science.gov (United States)

Balamurugan, A. M.; Sivasubramanian, A.; Parvathavarthini, B.

2017-12-01

The optical burst switching (OBS) is a promising technology that could meet the fast growing network demand. They are featured with the ability to meet the bandwidth requirement of applications that demand intensive bandwidth. OBS proves to be a satisfactory technology to tackle the huge bandwidth constraints, but suffers from security vulnerabilities. The objective of this proposed work is to design a faster and efficient burst header authentication algorithm for core nodes. There are two important key features in this work, viz., header encryption and authentication. Since the burst header is an important in optical burst switched network, it has to be encrypted; otherwise it is be prone to attack. The proposed MD5&RC4-4S based burst header authentication algorithm runs 20.75 ns faster than the conventional algorithms. The modification suggested in the proposed RC4-4S algorithm gives a better security and solves the correlation problems between the publicly known outputs during key generation phase. The modified MD5 recommended in this work provides 7.81 % better avalanche effect than the conventional algorithm. The device utilization result also shows the suitability of the proposed algorithm for header authentication in real time applications.

The modulatory effect of adaptive deep brain stimulation on beta bursts in Parkinson's disease.

Science.gov (United States)

Tinkhauser, Gerd; Pogosyan, Alek; Little, Simon; Beudel, Martijn; Herz, Damian M; Tan, Huiling; Brown, Peter

2017-04-01

Adaptive deep brain stimulation uses feedback about the state of neural circuits to control stimulation rather than delivering fixed stimulation all the time, as currently performed. In patients with Parkinson's disease, elevations in beta activity (13-35 Hz) in the subthalamic nucleus have been demonstrated to correlate with clinical impairment and have provided the basis for feedback control in trials of adaptive deep brain stimulation. These pilot studies have suggested that adaptive deep brain stimulation may potentially be more effective, efficient and selective than conventional deep brain stimulation, implying mechanistic differences between the two approaches. Here we test the hypothesis that such differences arise through differential effects on the temporal dynamics of beta activity. The latter is not constantly increased in Parkinson's disease, but comes in bursts of different durations and amplitudes. We demonstrate that the amplitude of beta activity in the subthalamic nucleus increases in proportion to burst duration, consistent with progressively increasing synchronization. Effective adaptive deep brain stimulation truncated long beta bursts shifting the distribution of burst duration away from long duration with large amplitude towards short duration, lower amplitude bursts. Critically, bursts with shorter duration are negatively and bursts with longer duration positively correlated with the motor impairment off stimulation. Conventional deep brain stimulation did not change the distribution of burst durations. Although both adaptive and conventional deep brain stimulation suppressed mean beta activity amplitude compared to the unstimulated state, this was achieved by a selective effect on burst duration during adaptive deep brain stimulation, whereas conventional deep brain stimulation globally suppressed beta activity. We posit that the relatively selective effect of adaptive deep brain stimulation provides a rationale for why this approach could

Intermittency in branching models

International Nuclear Information System (INIS)

Chiu, C.B.; Texas Univ., Austin; Hwa, R.C.; Oregon Univ., Eugene

1990-01-01

The intermittency properties of three branching models have been investigated. The factorial moments show power-law behavior as function of small rapidity width. The slopes and energy dependences reveal different characteristics of the models. The gluon model has the weakest intermittency. (orig.)

Solar Drift-Pair Bursts

Science.gov (United States)

Stanislavsky, A.; Volvach, Ya.; Konovalenko, A.; Koval, A.

2017-08-01

In this paper a new sight on the study of solar bursts historically called drift pairs (DPs) is presented. Having a simple morphology on dynamic spectra of radio records (two short components separated in time, and often they are very similar) and discovered at the dawn of radio astronomy, their features remain unexplained totally up to now. Generally, the DPs are observed during the solar storms of type III bursts, but not every storm of type III bursts is linked with DPs. Detected by ground-based instruments at decameter and meter wavelengths, the DP bursts are limited in frequency bandwidth. They can drift from high frequencies to low ones and vice versa. Their frequency drift rate may be both lower and higher than typical rates of type III bursts at the same frequency range. The development of low-frequency radio telescopes and data processing provide additional possibilities in the research. In this context the fresh analysis of DPs, made from recent observations in the summer campaign of 2015, are just considered. Their study was implemented by updated tools of the UTR-2 radio telescope at 9-33 MHz. During 10-12 July of 2015, DPs forming the longest patterns on dynamic spectra are about 7% of the total number of recorded DPs. Their marvelous resemblance in frequency drift rates with the solar S-bursts is discussed.

30 CFR 57.3461 - Rock bursts.

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Rock bursts. 57.3461 Section 57.3461 Mineral...-Underground Only § 57.3461 Rock bursts. (a) Operators of mines which have experienced a rock burst shall— (1) Within twenty four hours report to the nearest MSHA office each rock burst which: (i) Causes persons to...

X-Ray Spectral Characteristics of Ginga Gamma-Ray Bursts

International Nuclear Information System (INIS)

Strohmayer, T.E.; Fenimore, E.E.; Murakami, T.; Yoshida, A.

1998-01-01

We have investigated the spectral characteristics of a sample of bright gamma-ray bursts detected with the gamma-ray burst sensors aboard the satellite Ginga. This instrument employed a proportional and scintillation counter to provide sensitivity to photons in the 2 endash 400 keV region and as such provided a unique opportunity to characterize the largely unexplored X-ray properties of gamma-ray bursts. The photon spectra of the Ginga bursts are well described by a low-energy slope, a bend energy, and a high-energy slope. In the energy range where they can be compared, this result is consistent with burst spectral analyses obtained from the BATSE experiment aboard the Compton Gamma-Ray Observatory. However, below 20 keV we find evidence for a positive spectral number index in approximately 40% of our burst sample, with some evidence for a strong rolloff at lower energies in a few events. There is a correlation (Pearson's r = -0.62) between the low-energy slope and the bend energy. We find that the distribution of spectral bend energies extends below 10 keV. There has been some concern in cosmological models of gamma-ray bursts (GRBs) that the bend energy covers only a small dynamic range. Our result extends the observed dynamic range, and, since we observe bend energies down to the limit of our instrument, perhaps observations have not yet limited the range. The Ginga trigger range was virtually the same as that of BATSE, yet we find a different range of fit parameters. One possible explanation might be that GRBs have two break energies, one often in the 50 endash 500 keV range and the other near 5 keV. Both BATSE and Ginga fit with only a single break energy, so BATSE tends to find breaks near the center of its energy range, and we tend to find breaks in our energy range. The observed ratio of energy emitted in the X-rays relative to the gamma rays can be much larger than a few percent and, in fact, is sometimes larger than unity. The average for our 22 bursts

The Drift Burst Hypothesis

OpenAIRE

Christensen, Kim; Oomen, Roel; Renò, Roberto

2016-01-01

The Drift Burst Hypothesis postulates the existence of short-lived locally explosive trends in the price paths of financial assets. The recent US equity and Treasury flash crashes can be viewed as two high profile manifestations of such dynamics, but we argue that drift bursts of varying magnitude are an expected and regular occurrence in financial markets that can arise through established mechanisms such as feedback trading. At a theoretical level, we show how to build drift bursts into the...

Metabolic Effects of Intermittent Fasting.

Science.gov (United States)

Patterson, Ruth E; Sears, Dorothy D

2017-08-21

The objective of this review is to provide an overview of intermittent fasting regimens, summarize the evidence on the health benefits of intermittent fasting, and discuss physiological mechanisms by which intermittent fasting might lead to improved health outcomes. A MEDLINE search was performed using PubMed and the terms "intermittent fasting," "fasting," "time-restricted feeding," and "food timing." Modified fasting regimens appear to promote weight loss and may improve metabolic health. Several lines of evidence also support the hypothesis that eating patterns that reduce or eliminate nighttime eating and prolong nightly fasting intervals may result in sustained improvements in human health. Intermittent fasting regimens are hypothesized to influence metabolic regulation via effects on (a) circadian biology, (b) the gut microbiome, and (c) modifiable lifestyle behaviors, such as sleep. If proven to be efficacious, these eating regimens offer promising nonpharmacological approaches to improving health at the population level, with multiple public health benefits.

Lateralization of noise-burst trains based on onset and ongoing interaural delays.

Science.gov (United States)

Freyman, Richard L; Balakrishnan, Uma; Zurek, Patrick M

2010-07-01

The lateralization of 250-ms trains of brief noise bursts was measured using an acoustic pointing technique. Stimuli were designed to assess the contribution of the interaural time delay (ITD) of the onset binaural burst relative to that of the ITDs in the ongoing part of the train. Lateralization was measured by listeners' adjustments of the ITD of a pointer stimulus, a 50-ms burst of noise, to match the lateral position of the target train. Results confirmed previous reports of lateralization dominance by the onset burst under conditions in which the train is composed of frozen tokens and the ongoing part contains multiple ambiguous interaural delays. In contrast, lateralization of ongoing trains in which fresh noise tokens were used for each set of two alternating (left-leading/right-leading) binaural pairs followed the ITD of the first pair in each set, regardless of the ITD of the onset burst of the entire stimulus and even when the onset burst was removed by gradual gating. This clear lateralization of a long-duration stimulus with ambiguous interaural delay cues suggests precedence mechanisms that involve not only the interaural cues at the beginning of a sound, but also the pattern of cues within an ongoing sound.

X-ray bursts observed with JEM-X

DEFF Research Database (Denmark)

Brandt, Søren Kristian; Chenevez, Jérôme; Lund, Niels

2006-01-01

We report on the search for X-ray bursts in the JEM-X X-ray monitor on INTEGRAL during the first two years of operations. More than 350 bursts from 25 different type-I X-ray burst sources were found.......We report on the search for X-ray bursts in the JEM-X X-ray monitor on INTEGRAL during the first two years of operations. More than 350 bursts from 25 different type-I X-ray burst sources were found....

Intermittency in Complex Flows

Science.gov (United States)

Ben Mahjoub, Otman; Redondo, Jose M.

2017-04-01

turbulent mixing is a subject of great importance because it has a broad range of practical applications. In the chemical industry in particular mixing is desirable to facilitate fast mixing of reactants coupled with PIV, and on other methods used in experimental fluids mechanics, both in Eulerian and Lagrangian frameworks towards the understanding of molecular mixing and the role of vorticity and helicity in the analysis of stream function parameter oundaries of spatial dynamic features. Already we used multi-fractal analysis techniques and apply these techniques to understand the scale to scale transport related to mixing and the velocity structure function,used by [1, 2] in the form ⟨| δul |p⟩ ∝ ⟨| δul |s⟩ζp/ζs where ζp/ζs is a general relative scaling exponent that can be expressed as dlog⟨| δul |p⟩ ζp/ζs = -----s- dlog⟨| δul | ⟩ In these relations ζp can be different from ξp for odd values of p because absolute values of velocity increments are used. Clearly, the scale-invariance for relative exponents when ζp and ζs are scale-dependent cannot be easily interpreted. We estimate different intermittency parameters as a function of local instability e.g. Kelvin/Helmholtz, Rayleigh-Taylor or Holbmoe. Different scalar interfaces show different structures, that also depend on local Richardsons numbers, this may be due to different levels of intermittency and thus different spectra, which are not necessarily inertial nor in equilibrium. the analysis of the statistical properties of the velocity structure function is performed using a relative scaling. In the areas of breaking-induced turbulence and foam, which corespond to active, highly intermittent, turbulent regions, using(ESS), we define local intermittency at different depths and horizontal positions. The deviation from the -5/3 law for the power spectra at certain positions is clear, (PDF) of velocity differences highly deviate from a gaussian distribution, and depend on the depth or with

Randomized controlled trial comparing nasal intermittent positive pressure ventilation and nasal continuous positive airway pressure in premature infants after tracheal extubation

Directory of Open Access Journals (Sweden)

Daniela Franco Rizzo Komatsu

Full Text Available Summary Objective: To analyze the frequency of extubation failure in premature infants using conventional mechanical ventilation (MV after extubation in groups subjected to nasal intermittent positive pressure ventilation (nIPPV and continuous positive airway pressure (nCPAP. Method: Seventy-two premature infants with respiratory failure were studied, with a gestational age (GA ≤ 36 weeks and birth weight (BW > 750 g, who required tracheal intubation and mechanical ventilation. The study was controlled and randomized in order to ensure that the members of the groups used in the research were chosen at random. Randomization was performed at the time of extubation using sealed envelopes. Extubation failure was defined as the need for re-intubation and mechanical ventilation during the first 72 hours after extubation. Results: Among the 36 premature infants randomized to nIPPV, six (16.6% presented extubation failure in comparison to 11 (30.5% of the 36 premature infants randomized to nCPAP. There was no statistical difference between the two study groups regarding BW, GA, classification of the premature infant, and MV time. The main cause of extubation failure was the occurrence of apnea. Gastrointestinal and neurological complications did not occur in the premature infants participating in the study. Conclusion: We found that, despite the extubation failure of the group of premature infants submitted to nIPPV being numerically smaller than in premature infants submitted to nCPAP, there was no statistically significant difference between the two modes of ventilatory support after extubation.

UWB dual burst transmit driver

Science.gov (United States)

Dallum, Gregory E [Livermore, CA; Pratt, Garth C [Discovery Bay, CA; Haugen, Peter C [Livermore, CA; Zumstein, James M [Livermore, CA; Vigars, Mark L [Livermore, CA; Romero, Carlos E [Livermore, CA

2012-04-17

A dual burst transmitter for ultra-wideband (UWB) communication systems generates a pair of precisely spaced RF bursts from a single trigger event. An input trigger pulse produces two oscillator trigger pulses, an initial pulse and a delayed pulse, in a dual trigger generator. The two oscillator trigger pulses drive a gated RF burst (power output) oscillator. A bias driver circuit gates the RF output oscillator on and off and sets the RF burst packet width. The bias driver also level shifts the drive signal to the level that is required for the RF output device.

QUASI-PERIODIC OSCILLATIONS AND BROADBAND VARIABILITY IN SHORT MAGNETAR BURSTS

Energy Technology Data Exchange (ETDEWEB)

Huppenkothen, Daniela; Watts, Anna L.; Uttley, Phil; Van der Horst, Alexander J.; Van der Klis, Michiel [Astronomical Institute ' ' Anton Pannekoek' ' , University of Amsterdam, Postbus 94249, 1090-GE Amsterdam (Netherlands); Kouveliotou, Chryssa [Office of Science and Technology, ZP12, NASA Marshall Space Flight Center, Huntsville, AL 35812 (United States); Goegues, Ersin [Sabanc Latin-Small-Letter-Dotless-I University, Orhanl Latin-Small-Letter-Dotless-I -Tuzla, Istanbul 34956 (Turkey); Granot, Jonathan [The Open University of Israel, 1 University Road, P.O. Box 808, Ra' anana 43537 (Israel); Vaughan, Simon [X-Ray and Observational Astronomy Group, University of Leicester, Leicester LE1 7RH (United Kingdom); Finger, Mark H., E-mail: D.Huppenkothen@uva.nl [Universities Space Research Association, Huntsville, AL 35805 (United States)

2013-05-01

The discovery of quasi-periodic oscillations (QPOs) in magnetar giant flares has opened up prospects for neutron star asteroseismology. However, with only three giant flares ever recorded, and only two with data of sufficient quality to search for QPOs, such analysis is seriously data limited. We set out a procedure for doing QPO searches in the far more numerous, short, less energetic magnetar bursts. The short, transient nature of these bursts requires the implementation of sophisticated statistical techniques to make reliable inferences. Using Bayesian statistics, we model the periodogram as a combination of red noise at low frequencies and white noise at high frequencies, which we show is a conservative approach to the problem. We use empirical models to make inferences about the potential signature of periodic and QPOs at these frequencies. We compare our method with previously used techniques and find that although it is on the whole more conservative, it is also more reliable in ruling out false positives. We illustrate our Bayesian method by applying it to a sample of 27 bursts from the magnetar SGR J0501+4516 observed by the Fermi Gamma-ray Burst Monitor, and we find no evidence for the presence of QPOs in any of the bursts in the unbinned spectra, but do find a candidate detection in the binned spectra of one burst. However, whether this signal is due to a genuine quasi-periodic process, or can be attributed to unmodeled effects in the noise is at this point a matter of interpretation.

Solar X-ray bursts

International Nuclear Information System (INIS)

Urnov, A.M.

1980-01-01

In the popular form the consideration is given to the modern state tasks and results of X-ray spectrometry of solar bursts. The operation of X-ray spectroheliograph is described. Results of spectral and polarization measurings of X-ray radiation of one powerful solar burst are presented. The conclusion has been drawn that in the process of burst development three characteristic stages may be distingwished: 1) the initial phase; just in this period processes which lead to observed consequences-electromagnetic and corpuscular radiation are born; 2) the impulse phase, or the phase of maximum, is characterised by sharp increase of radiation flux. During this phase the main energy content emanates and some volumes of plasma warm up to high temperatures; 3) the phase of burst damping, during which plasma cools and reverts to the initial condition

Multiple Signal Classification for Gravitational Wave Burst Search

Science.gov (United States)

Cao, Junwei; He, Zhengqi

2013-01-01

This work is mainly focused on the application of the multiple signal classification (MUSIC) algorithm for gravitational wave burst search. This algorithm extracts important gravitational wave characteristics from signals coming from detectors with arbitrary position, orientation and noise covariance. In this paper, the MUSIC algorithm is described in detail along with the necessary adjustments required for gravitational wave burst search. The algorithm's performance is measured using simulated signals and noise. MUSIC is compared with the Q-transform for signal triggering and with Bayesian analysis for direction of arrival (DOA) estimation, using the Ω-pipeline. Experimental results show that MUSIC has a lower resolution but is faster. MUSIC is a promising tool for real-time gravitational wave search for multi-messenger astronomy.

Cosmic Rays in Intermittent Magnetic Fields

International Nuclear Information System (INIS)

Shukurov, Anvar; Seta, Amit; Bushby, Paul J.; Wood, Toby S.; Snodin, Andrew P.

2017-01-01

The propagation of cosmic rays in turbulent magnetic fields is a diffusive process driven by the scattering of the charged particles by random magnetic fluctuations. Such fields are usually highly intermittent, consisting of intense magnetic filaments and ribbons surrounded by weaker, unstructured fluctuations. Studies of cosmic-ray propagation have largely overlooked intermittency, instead adopting Gaussian random magnetic fields. Using test particle simulations, we calculate cosmic-ray diffusivity in intermittent, dynamo-generated magnetic fields. The results are compared with those obtained from non-intermittent magnetic fields having identical power spectra. The presence of magnetic intermittency significantly enhances cosmic-ray diffusion over a wide range of particle energies. We demonstrate that the results can be interpreted in terms of a correlated random walk.

Cosmic Rays in Intermittent Magnetic Fields

Energy Technology Data Exchange (ETDEWEB)

Shukurov, Anvar; Seta, Amit; Bushby, Paul J.; Wood, Toby S. [School of Mathematics and Statistics, Newcastle University, Newcastle Upon Tyne NE1 7RU (United Kingdom); Snodin, Andrew P., E-mail: a.seta1@ncl.ac.uk, E-mail: amitseta90@gmail.com [Department of Mathematics, Faculty of Applied Science, King Mongkut’s University of Technology North Bangkok, Bangkok 10800 (Thailand)

2017-04-10

The propagation of cosmic rays in turbulent magnetic fields is a diffusive process driven by the scattering of the charged particles by random magnetic fluctuations. Such fields are usually highly intermittent, consisting of intense magnetic filaments and ribbons surrounded by weaker, unstructured fluctuations. Studies of cosmic-ray propagation have largely overlooked intermittency, instead adopting Gaussian random magnetic fields. Using test particle simulations, we calculate cosmic-ray diffusivity in intermittent, dynamo-generated magnetic fields. The results are compared with those obtained from non-intermittent magnetic fields having identical power spectra. The presence of magnetic intermittency significantly enhances cosmic-ray diffusion over a wide range of particle energies. We demonstrate that the results can be interpreted in terms of a correlated random walk.

Monitoring burst (M-burst) — A novel framework of failure localization in all-optical mesh networks

KAUST Repository

Ali, Mohammed L.; Ho, Pin-Han; Wu, Bin; Tapolcai, Janos; Shihada, Basem

2011-01-01

Achieving instantaneous and precise failure localization in all-optical wavelength division multiplexing (WDM) networks has been an attractive feature of network fault management systems, and is particularly important when failure-dependent protection is employed. The paper introduces a novel framework of real-time failure localization in all-optical WDM mesh networks, called monitoring-burst (m-burst), which aims to initiate a graceful compromise between consumed monitoring resources and monitoring delay. Different from any previously reported solution, the proposed m-burst framework has a single monitoring node (MN) which launches optical bursts along a set of pre-defined close-loop routes, called monitoring cycles (m-cycles), to probe the links along the m-cycles. Bursts along different m-cycles are kept non-overlapping through any link of the network. By identifying the lost bursts due to single link failure events only, the MN can unambiguously localize the failed link in at least 3-connected networks. We will justify the feasibility and applicability of the proposed m-burst framework in the scenario of interest. To avoid possible collision among optical bursts launched by the MN, we define the problem of collision-free scheduling and formulate it into an integer linear program (ILP) in order to minimize the monitoring delay. Numerical results demonstrate the effectiveness of the proposed framework and the proposed solution.

Monitoring burst (M-burst) — A novel framework of failure localization in all-optical mesh networks

KAUST Repository

Ali, Mohammed L.

2011-10-10

Achieving instantaneous and precise failure localization in all-optical wavelength division multiplexing (WDM) networks has been an attractive feature of network fault management systems, and is particularly important when failure-dependent protection is employed. The paper introduces a novel framework of real-time failure localization in all-optical WDM mesh networks, called monitoring-burst (m-burst), which aims to initiate a graceful compromise between consumed monitoring resources and monitoring delay. Different from any previously reported solution, the proposed m-burst framework has a single monitoring node (MN) which launches optical bursts along a set of pre-defined close-loop routes, called monitoring cycles (m-cycles), to probe the links along the m-cycles. Bursts along different m-cycles are kept non-overlapping through any link of the network. By identifying the lost bursts due to single link failure events only, the MN can unambiguously localize the failed link in at least 3-connected networks. We will justify the feasibility and applicability of the proposed m-burst framework in the scenario of interest. To avoid possible collision among optical bursts launched by the MN, we define the problem of collision-free scheduling and formulate it into an integer linear program (ILP) in order to minimize the monitoring delay. Numerical results demonstrate the effectiveness of the proposed framework and the proposed solution.

Intermittent electron density and temperature fluctuations and associated fluxes in the Alcator C-Mod scrape-off layer

Science.gov (United States)

Kube, R.; Garcia, O. E.; Theodorsen, A.; Brunner, D.; Kuang, A. Q.; LaBombard, B.; Terry, J. L.

2018-06-01

The Alcator C-Mod mirror Langmuir probe system has been used to sample data time series of fluctuating plasma parameters in the outboard mid-plane far scrape-off layer. We present a statistical analysis of one second long time series of electron density, temperature, radial electric drift velocity and the corresponding particle and electron heat fluxes. These are sampled during stationary plasma conditions in an ohmically heated, lower single null diverted discharge. The electron density and temperature are strongly correlated and feature fluctuation statistics similar to the ion saturation current. Both electron density and temperature time series are dominated by intermittent, large-amplitude burst with an exponential distribution of both burst amplitudes and waiting times between them. The characteristic time scale of the large-amplitude bursts is approximately 15 μ {{s}}. Large-amplitude velocity fluctuations feature a slightly faster characteristic time scale and appear at a faster rate than electron density and temperature fluctuations. Describing these time series as a superposition of uncorrelated exponential pulses, we find that probability distribution functions, power spectral densities as well as auto-correlation functions of the data time series agree well with predictions from the stochastic model. The electron particle and heat fluxes present large-amplitude fluctuations. For this low-density plasma, the radial electron heat flux is dominated by convection, that is, correlations of fluctuations in the electron density and radial velocity. Hot and dense blobs contribute only a minute fraction of the total fluctuation driven heat flux.

Imaging spectroscopy of type U and J solar radio bursts with LOFAR

Science.gov (United States)

Reid, Hamish A. S.; Kontar, Eduard P.

2017-10-01

Context. Radio U-bursts and J-bursts are signatures of electron beams propagating along magnetic loops confined to the corona. The more commonly observed type III radio bursts are signatures of electron beams propagating along magnetic loops that extend into interplanetary space. Given the prevalence of solar magnetic flux to be closed in the corona, why type III bursts are more frequently observed than U-bursts or J-bursts is an outstanding question. Aims: We use Low-Frequency Array (LOFAR) imaging spectroscopy between 30-80 MHz of low-frequency U-bursts and J-bursts, for the first time, to understand why electron beams travelling along coronal loops produce radio emission less often. Radio burst observations provide information not only about the exciting electron beams but also about the structure of large coronal loops with densities that are too low for standard extreme ultraviolet (EUV) or X-ray analysis. Methods: We analysed LOFAR images of a sequence of two J-bursts and one U-burst. The different radio source positions were used to model the spatial structure of the guiding magnetic flux tube and then deduce the energy range of the exciting electron beams without the assumption of a standard density model. We also estimated the electron density along the magnetic flux rope and compared it to coronal models. Results: The radio sources infer a magnetic loop that is 1 solar radius in altitude with the highest frequency sources starting around 0.6 solar radii. Electron velocities were found between 0.13 c and 0.24 c with the front of the electron beam travelling faster than the back of the electron beam. The velocities correspond to energy ranges within the beam from 0.7-11 keV to 0.7-43 keV. The density along the loop is higher than typical coronal density models and the density gradient is smaller. Conclusions: We found that a more restrictive range of accelerated beam and background plasma parameters can result in U-bursts or J-bursts, causing type III

An Exact Solution of the Gamma Ray Burst Arrival Time Analysis ...

Indian Academy of Sciences (India)

R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

An Exact Solution of the Gamma Ray Burst Arrival Time Analysis. Problem. S. Sinha ISRO Satellite Center, Bangalore 560 017, India. Abstract. An analytical solution of the GRB arrival time analysis is presented. The errors in the position of the GRB resulting from timing and position errors of different satellites are calculated.

Focused study of thermonuclear bursts on neutron stars

DEFF Research Database (Denmark)

Chenevez, Jérôme

radius expansion bursts likely eject nuclear burning ashes into the interstellar medium, and may make possible the detection of photoionization edges. Indeed, Theoretical models predict that absorption edges from 58Fe at 9.2 keV, 60Zn and 62Zn at 12.2 keV should be detectable by Simbol X. A positive...

Localization of Gamma-Ray Bursts Using the Fermi Gamma-Ray Burst Monitor

NARCIS (Netherlands)

Connaughton, V.; Briggs, M.S.; Goldstein, A.; Meegan, C.A.; Paciesas, W.S.; Preece, R.D.; Wilson-Hodge, C.A.; Gibby, M.H.; Greiner, J.; Gruber, D.; Jenke, P.; Kippen, R.M.; Pelassa, V.; Xiong, S.; Yu, H-F.; Bhat, P.N.; Burgess, J.M.; Byrne, D.; Fitzpatrick, G.; Foley, S.; Giles, M.M.; Guiriec, S.; van der Horst, A.J.; von Kienlin, A.; McBreen, S.; McGlynn, S.; Tierney, D.; Zhang, B..B.

2015-01-01

The Fermi Gamma-ray Burst Monitor (GBM) has detected over 1400 gamma-ray bursts (GRBs) since it began science operations in 2008 July. We use a subset of over 300 GRBs localized by instruments such as Swift, the Fermi Large Area Telescope, INTEGRAL, and MAXI, or through triangulations from the

Light Dawns on Dark Gamma-ray Bursts

Science.gov (United States)

2010-12-01

Gamma-ray bursts are among the most energetic events in the Universe, but some appear curiously faint in visible light. The biggest study to date of these so-called dark gamma-ray bursts, using the GROND instrument on the 2.2-metre MPG/ESO telescope at La Silla in Chile, has found that these gigantic explosions don't require exotic explanations. Their faintness is now fully explained by a combination of causes, the most important of which is the presence of dust between the Earth and the explosion. Gamma-ray bursts (GRBs), fleeting events that last from less than a second to several minutes, are detected by orbiting observatories that can pick up their high energy radiation. Thirteen years ago, however, astronomers discovered a longer-lasting stream of less energetic radiation coming from these violent outbursts, which can last for weeks or even years after the initial explosion. Astronomers call this the burst's afterglow. While all gamma-ray bursts [1] have afterglows that give off X-rays, only about half of them were found to give off visible light, with the rest remaining mysteriously dark. Some astronomers suspected that these dark afterglows could be examples of a whole new class of gamma-ray bursts, while others thought that they might all be at very great distances. Previous studies had suggested that obscuring dust between the burst and us might also explain why they were so dim. "Studying afterglows is vital to further our understanding of the objects that become gamma-ray bursts and what they tell us about star formation in the early Universe," says the study's lead author Jochen Greiner from the Max-Planck Institute for Extraterrestrial Physics in Garching bei München, Germany. NASA launched the Swift satellite at the end of 2004. From its orbit above the Earth's atmosphere it can detect gamma-ray bursts and immediately relay their positions to other observatories so that the afterglows could be studied. In the new study, astronomers combined Swift

Randomized, controlled trial comparing synchronized intermittent mandatory ventilation and synchronized intermittent mandatory ventilation plus pressure support in preterm infants.

Science.gov (United States)

Reyes, Zenaida C; Claure, Nelson; Tauscher, Markus K; D'Ugard, Carmen; Vanbuskirk, Silvia; Bancalari, Eduardo

2006-10-01

Prolonged mechanical ventilation is associated with lung injury in preterm infants. In these infants, weaning from synchronized intermittent mandatory ventilation may be delayed by their inability to cope with increased respiratory loads. The addition of pressure support to synchronized intermittent mandatory ventilation can offset these loads and may facilitate weaning. The purpose of this work was to compare synchronized intermittent mandatory ventilation and synchronized intermittent mandatory ventilation plus pressure support in weaning from mechanical ventilation and the duration of supplemental oxygen dependency in preterm infants with respiratory failure. Preterm infants weighing 500 to 1000 g at birth who required mechanical ventilation during the first postnatal week were randomly assigned to synchronized intermittent mandatory ventilation or synchronized intermittent mandatory ventilation plus pressure support. In both groups, weaning followed a set protocol during the first 28 days. Outcomes were assessed during the first 28 days and until discharge or death. There were 107 infants enrolled (53 synchronized intermittent mandatory ventilation plus pressure support and 54 synchronized intermittent mandatory ventilation). Demographic and perinatal data, mortality, and morbidity did not differ between groups. During the first 28 days, infants in the synchronized intermittent mandatory ventilation plus pressure support group reached minimal ventilator settings and were extubated earlier than infants in the synchronized intermittent mandatory ventilation group. Total duration of mechanical ventilation, duration of oxygen dependency, and oxygen need at 36 weeks' postmenstrual age alone or combined with death did not differ between groups. However, infants in synchronized intermittent mandatory ventilation plus pressure support within the 700- to 1000-g birth weight strata had a shorter oxygen dependency. The results of this study suggest that the addition of

The afterglow of GRB 050709 and the nature of the short-hard gamma-ray bursts.

Science.gov (United States)

Fox, D B; Frail, D A; Price, P A; Kulkarni, S R; Berger, E; Piran, T; Soderberg, A M; Cenko, S B; Cameron, P B; Gal-Yam, A; Kasliwal, M M; Moon, D-S; Harrison, F A; Nakar, E; Schmidt, B P; Penprase, B; Chevalier, R A; Kumar, P; Roth, K; Watson, D; Lee, B L; Shectman, S; Phillips, M M; Roth, M; McCarthy, P J; Rauch, M; Cowie, L; Peterson, B A; Rich, J; Kawai, N; Aoki, K; Kosugi, G; Totani, T; Park, H-S; MacFadyen, A; Hurley, K C

2005-10-06

The final chapter in the long-standing mystery of the gamma-ray bursts (GRBs) centres on the origin of the short-hard class of bursts, which are suspected on theoretical grounds to result from the coalescence of neutron-star or black-hole binary systems. Numerous searches for the afterglows of short-hard bursts have been made, galvanized by the revolution in our understanding of long-duration GRBs that followed the discovery in 1997 of their broadband (X-ray, optical and radio) afterglow emission. Here we present the discovery of the X-ray afterglow of a short-hard burst, GRB 050709, whose accurate position allows us to associate it unambiguously with a star-forming galaxy at redshift z = 0.160, and whose optical lightcurve definitively excludes a supernova association. Together with results from three other recent short-hard bursts, this suggests that short-hard bursts release much less energy than the long-duration GRBs. Models requiring young stellar populations, such as magnetars and collapsars, are ruled out, while coalescing degenerate binaries remain the most promising progenitor candidates.

Intermittency in 197Au fragmentation

International Nuclear Information System (INIS)

Dabrowska, A.; Holynski, R.; Olszewski, A.; Szarska, M.; Wilczynska, B.; Wolter, W.; Wosiek, B.; Cherry, M.L.; Deines-Jones, P.; Jones, W.V.; Sengupta, K.; Wefel, B.

1995-07-01

The concept of factorial moments was applied to an analysis of the dynamical fluctuations in the charge distributions of the fragments emitted from gold nuclei with energies 10.6 and < 1.0 GeV/n interacting with emulsion nuclei. Clear evidence for intermittent fluctuations has been found in an analysis using all the particles released from the gold projectile, with a stronger effect observed below 1 GeV/n than at 10.6 GeV/n. For the full data sets, however, the intermittency effect was found to be very sensitive to the singly charged particles, and neglecting these particles strongly reduces the intermittency signal. When the analysis is restricted to the multiply charged fragments, an intermittency effect is revealed only for multifragmentation events, although one that is enhanced as compared to the analysis of all, singly and multiply charged, particles. The properties of the anomalous fractal dimensions suggest a sequential decay mechanism, rather than the existence of possible critical behaviour in the process of nuclear fragmentation. The likely influence of the charge conservation effects and the finite size of decaying systems on the observed intermittency signals was pointed out. (author). 37 refs, 9 figs, 5 tabs

X-Ray Bursts from NGC 6652

Science.gov (United States)

Morgan, Edward

The possibly transient X-ray Source in the globular cluster NGC 6652 has been seen by BeppoSax and the ASM on RXTE to undergo X-ray bursts, possibly Type I. Very little is known about this X-ray source, and confirmation of its bursts type-I nature would identify it as a neutron star binary. Type I bursts in 6 other sources have been shown to exhibit intervals of millisecond ocsillation that most likely indicate the neutron star spin period. Radius-expansion bursts can reveal information about the mass and size of the neutron star. We propose to use the ASM to trigger an observation of this source to maximize the probability of catching a burst in the PCA.

Transitions to Synchrony in Coupled Bursting Neurons

Science.gov (United States)

Dhamala, Mukeshwar; Jirsa, Viktor K.; Ding, Mingzhou

2004-01-01

Certain cells in the brain, for example, thalamic neurons during sleep, show spike-burst activity. We study such spike-burst neural activity and the transitions to a synchronized state using a model of coupled bursting neurons. In an electrically coupled network, we show that the increase of coupling strength increases incoherence first and then induces two different transitions to synchronized states, one associated with bursts and the other with spikes. These sequential transitions to synchronized states are determined by the zero crossings of the maximum transverse Lyapunov exponents. These results suggest that synchronization of spike-burst activity is a multi-time-scale phenomenon and burst synchrony is a precursor to spike synchrony.

Transitions to synchrony in coupled bursting neurons

International Nuclear Information System (INIS)

Dhamala, Mukeshwar; Jirsa, Viktor K.; Ding Mingzhou

2004-01-01

Certain cells in the brain, for example, thalamic neurons during sleep, show spike-burst activity. We study such spike-burst neural activity and the transitions to a synchronized state using a model of coupled bursting neurons. In an electrically coupled network, we show that the increase of coupling strength increases incoherence first and then induces two different transitions to synchronized states, one associated with bursts and the other with spikes. These sequential transitions to synchronized states are determined by the zero crossings of the maximum transverse Lyapunov exponents. These results suggest that synchronization of spike-burst activity is a multi-time-scale phenomenon and burst synchrony is a precursor to spike synchrony

Intermittent control: a computational theory of human control.

Science.gov (United States)

Gawthrop, Peter; Loram, Ian; Lakie, Martin; Gollee, Henrik

2011-02-01

The paradigm of continuous control using internal models has advanced understanding of human motor control. However, this paradigm ignores some aspects of human control, including intermittent feedback, serial ballistic control, triggered responses and refractory periods. It is shown that event-driven intermittent control provides a framework to explain the behaviour of the human operator under a wider range of conditions than continuous control. Continuous control is included as a special case, but sampling, system matched hold, an intermittent predictor and an event trigger allow serial open-loop trajectories using intermittent feedback. The implementation here may be described as "continuous observation, intermittent action". Beyond explaining unimodal regulation distributions in common with continuous control, these features naturally explain refractoriness and bimodal stabilisation distributions observed in double stimulus tracking experiments and quiet standing, respectively. Moreover, given that human control systems contain significant time delays, a biological-cybernetic rationale favours intermittent over continuous control: intermittent predictive control is computationally less demanding than continuous predictive control. A standard continuous-time predictive control model of the human operator is used as the underlying design method for an event-driven intermittent controller. It is shown that when event thresholds are small and sampling is regular, the intermittent controller can masquerade as the underlying continuous-time controller and thus, under these conditions, the continuous-time and intermittent controller cannot be distinguished. This explains why the intermittent control hypothesis is consistent with the continuous control hypothesis for certain experimental conditions.

The Second SWIFT Burst Alert Telescope (BAT) Gamma-Ray Burst Catalog

Science.gov (United States)

Sakamoto, T.; Barthelmy, S. D.; Baumgartner, W. H.; Cummings, J. R.; Fenimore, E. E.; Gehrels, N.; Krimm, H. A.; Markwardt, C. B.; Palmer, D. M.; Parsons, A. M.;

Stimulus induced bursts in severe postanoxic encephalopathy.

Science.gov (United States)

Tjepkema-Cloostermans, Marleen C; Wijers, Elisabeth T; van Putten, Michel J A M

2016-11-01

To report on a distinct effect of auditory and sensory stimuli on the EEG in comatose patients with severe postanoxic encephalopathy. In two comatose patients admitted to the Intensive Care Unit (ICU) with severe postanoxic encephalopathy and burst-suppression EEG, we studied the effect of external stimuli (sound and touch) on the occurrence of bursts. In patient A bursts could be induced by either auditory or sensory stimuli. In patient B bursts could only be induced by touching different facial regions (forehead, nose and chin). When stimuli were presented with relatively long intervals, bursts persistently followed the stimuli, while stimuli with short intervals (encephalopathy can be induced by external stimuli, resulting in stimulus-dependent burst-suppression. Stimulus induced bursts should not be interpreted as prognostic favourable EEG reactivity. Copyright © 2016 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

Stellar Sources of Gamma-ray Bursts

OpenAIRE

Luchkov, B. I.

2011-01-01

Correlation analysis of Swift gamma-ray burst coordinates and nearby star locations (catalog Gliese) reveals 4 coincidences with good angular accuracy. The random probability is 4\\times 10^{-5}, so evidencing that coincident stars are indeed gamma-ray burst sources. Some additional search of stellar gamma-ray bursts is discussed.

Neutrino burst identification in underground detectors

International Nuclear Information System (INIS)

Fulgione, W.; Mengotti-Silva, N.; Panaro, L.

1996-01-01

We discuss the problem of neutrino burst identification in underground ν-telescopes. First the usual statistical analysis based on the time structure of the events is reviewed, with special attention to the statistical significance of burst candidates. Next, we propose a second level analysis that can provide independent confirmation of burst detection. This exploits the spatial distribution of the single events of a burst candidate, and uses the formalism of the entropy of information. Examples of both techniques are shown, based on the LVD experiment at Gran Sasso. (orig.)

SGR J1550-5418 Bursts Detected with the Fermi Gamma-Ray Burst Monitor during Its Most Prolific Activity

Science.gov (United States)

vanderHorst, A. J.; Kouveliotou, C.; Gorgone, N. M.; Kaneko, Y.; Baring, M. G.; Guiriec, S.; Gogus, E,; Granot, J.; Watts, A. L.; Lin, L.;

Machine-z: Rapid Machine-Learned Redshift Indicator for Swift Gamma-Ray Bursts

Science.gov (United States)

Ukwatta, T. N.; Wozniak, P. R.; Gehrels, N.

2016-01-01

Studies of high-redshift gamma-ray bursts (GRBs) provide important information about the early Universe such as the rates of stellar collapsars and mergers, the metallicity content, constraints on the re-ionization period, and probes of the Hubble expansion. Rapid selection of high-z candidates from GRB samples reported in real time by dedicated space missions such as Swift is the key to identifying the most distant bursts before the optical afterglow becomes too dim to warrant a good spectrum. Here, we introduce 'machine-z', a redshift prediction algorithm and a 'high-z' classifier for Swift GRBs based on machine learning. Our method relies exclusively on canonical data commonly available within the first few hours after the GRB trigger. Using a sample of 284 bursts with measured redshifts, we trained a randomized ensemble of decision trees (random forest) to perform both regression and classification. Cross-validated performance studies show that the correlation coefficient between machine-z predictions and the true redshift is nearly 0.6. At the same time, our high-z classifier can achieve 80 per cent recall of true high-redshift bursts, while incurring a false positive rate of 20 per cent. With 40 per cent false positive rate the classifier can achieve approximately 100 per cent recall. The most reliable selection of high-redshift GRBs is obtained by combining predictions from both the high-z classifier and the machine-z regressor.

Gamma-ray burst observations with the Compton/Ulysses/Pioneer-Venus network

International Nuclear Information System (INIS)

Cline, T.L.; Hurley, K.C.; Sommer, M.; Boer, M.; Niel, M.; Fishman, G.J.; Kouveliotou, C.; Meegan, C.A.; Paciesas, W.S.; Wilson, R.B.; Fenimore, E.E.; Laros, J.G.; Klebesadel, R.W.

1993-01-01

The third and latest interplanetary network for the precise directional analysis of gamma ray bursts consists of the Burst and Transient Source Experiment in Compton Gamma Ray Observatory and instruments on Pioneer-Venus Orbiter and the deep-space mission Ulysses. The unsurpassed resolution of the BATSE instrument, the use of refined analysis techniques, and Ulysses' distance of up to 6 AU all contribute to a potential for greater precision than had been achieved with former networks. Also, the departure of Ulysses from the ecliptic plane in 1992 avoids any positional alignment of the three instruments that would lessen the source directional accuracy

From damselflies to pterosaurs: how burst and sustainable flight performance scale with size.

Science.gov (United States)

Marden, J H

1994-04-01

Recent empirical data for short-burst lift and power production of flying animals indicate that mass-specific lift and power output scale independently (lift) or slightly positively (power) with increasing size. These results contradict previous theory, as well as simple observation, which argues for degradation of flight performance with increasing size. Here, empirical measures of lift and power during short-burst exertion are combined with empirically based estimates of maximum muscle power output in order to predict how burst and sustainable performance scale with body size. The resulting model is used to estimate performance of the largest extant flying birds and insects, along with the largest flying animals known from fossils. These estimates indicate that burst flight performance capacities of even the largest extinct fliers (estimated mass 250 kg) would allow takeoff from the ground; however, limitations on sustainable power output should constrain capacity for continuous flight at body sizes exceeding 0.003-1.0 kg, depending on relative wing length and flight muscle mass.

A comparison of methods for gravitational wave burst searches from LIGO and Virgo

International Nuclear Information System (INIS)

Beauville, F; Buskulic, D; Grosjean, D; Bizouard, M-A; Cavalier, F; Clapson, A-C; Hello, P; Blackburn, L; Katsavounidis, E; Bosi, L; Brocco, L; Brown, D A; Chatterji, S; Christensen, N; Knight, M; Fairhurst, S; Guidi, G; Heng, S; Hewitson, M; Klimenko, S

2008-01-01

The search procedure for burst gravitational waves has been studied using 24 h of simulated data in a network of three interferometers (Hanford 4 km, Livingston 4 km and Virgo 3 km are the example interferometers). Several methods to detect burst events developed in the LIGO Scientific Collaboration (LSC) and Virgo Collaboration have been studied and compared. We have performed coincidence analysis of the triggers obtained in the different interferometers with and without simulated signals added to the data. The benefits of having multiple interferometers of similar sensitivity are demonstrated by comparing the detection performance of the joint coincidence analysis with LSC and Virgo only burst searches. Adding Virgo to the LIGO detector network can increase by 50% the detection efficiency for this search. Another advantage of a joint LIGO-Virgo network is the ability to reconstruct the source sky position. The reconstruction accuracy depends on the timing measurement accuracy of the events in each interferometer, and is displayed in this paper with a fixed source position example

A comparison of methods for gravitational wave burst searches from LIGO and Virgo

Energy Technology Data Exchange (ETDEWEB)

Beauville, F; Buskulic, D; Grosjean, D [Laboratoire d' Annecy-le-Vieux de Physique des Particules, Chemin de Bellevue, BP 110, 74941 Annecy-le-Vieux Cedex (France); Bizouard, M-A; Cavalier, F; Clapson, A-C; Hello, P [Laboratoire de l' Accelerateur Lineaire, IN2P3/CNRS-Universite de Paris XI, BP 34, 91898 Orsay Cedex (France); Blackburn, L; Katsavounidis, E [LIGO-Massachusetts Institute of Technology, Cambridge, MA 02139 (United States); Bosi, L [INFN Sezione di Perugia and/or Universita di Perugia, Via A Pascoli, I-06123 Perugia (Italy); Brocco, L [INFN Sezione di Roma and/or Universita ' La Sapienza' , P le A Moro 2, I-00185 Roma (Italy); Brown, D A; Chatterji, S [LIGO-California Institute of Technology, Pasadena, CA 91125 (United States); Christensen, N; Knight, M [Carleton College, Northfield, MN 55057 (United States); Fairhurst, S [University of Wisconsin-Milwaukee, Milwaukee, WI 53201 (United States); Guidi, G [INFN Sezione Firenze/Urbino Via G Sansone 1, I-50019 Sesto Fiorentino (Italy); and/or Universita di Firenze, Largo E Fermi 2, I-50125 Firenze and/or Universita di Urbino, Via S Chiara 27, I-61029 Urbino (Italy); Heng, S; Hewitson, M [University of Glasgow, Glasgow, G12 8QQ (United Kingdom); Klimenko, S [University of Florida-Gainesville, FL 32611 (United States)] (and others)

2008-02-21

The search procedure for burst gravitational waves has been studied using 24 h of simulated data in a network of three interferometers (Hanford 4 km, Livingston 4 km and Virgo 3 km are the example interferometers). Several methods to detect burst events developed in the LIGO Scientific Collaboration (LSC) and Virgo Collaboration have been studied and compared. We have performed coincidence analysis of the triggers obtained in the different interferometers with and without simulated signals added to the data. The benefits of having multiple interferometers of similar sensitivity are demonstrated by comparing the detection performance of the joint coincidence analysis with LSC and Virgo only burst searches. Adding Virgo to the LIGO detector network can increase by 50% the detection efficiency for this search. Another advantage of a joint LIGO-Virgo network is the ability to reconstruct the source sky position. The reconstruction accuracy depends on the timing measurement accuracy of the events in each interferometer, and is displayed in this paper with a fixed source position example.

INTEGRAL monitoring of unusually long X-ray bursts

DEFF Research Database (Denmark)

of the accreted material, these bursts may be explained by either the unstable burning of a large pile of mixed hydrogen and helium, or the ignition of a thick pure helium layer. Long duration bursts are particularly expected at very low accretion rates and make possible to study the transition from a hydrogen......Thermonuclear bursts on the surface of accreting neutron stars in low mass X-ray binaries have been studied for many years and have in a few cases confirmed theoretical models of nuclear ignition and burning mechanisms. The large majority of X-ray bursts last less than 100s. A good number......-rich bursting regime to a pure helium regime. Moreover, a handful of long bursts have shown, before the extended decay phase, an initial spike similar to a normal short X-ray burst. Such twofold bursts might be a sort of link between short and super-bursts, where the premature ignition of a carbon layer could...

Bursting synchronization in scale-free networks

International Nuclear Information System (INIS)

Batista, C.A.S.; Batista, A.M.; Pontes, J.C.A. de; Lopes, S.R.; Viana, R.L.

2009-01-01

Neuronal networks in some areas of the brain cortex present the scale-free property, i.e., the neuron connectivity is distributed according to a power-law, such that neurons are more likely to couple with other already well-connected ones. Neuron activity presents two timescales, a fast one related to action-potential spiking, and a slow timescale in which bursting takes place. Some pathological conditions are related with the synchronization of the bursting activity in a weak sense, meaning the adjustment of the bursting phase due to coupling. Hence it has been proposed that an externally applied time-periodic signal be applied in order to control undesirable synchronized bursting rhythms. We investigated this kind of intervention using a two-dimensional map to describe neurons with spiking-bursting activity in a scale-free network.

Exposure to intermittent hypoxia and sustained hypercapnia reduces therapeutic CPAP in participants with obstructive sleep apnea.

Science.gov (United States)

El-Chami, Mohamad; Sudan, Sukhesh; Lin, Ho-Sheng; Mateika, Jason H

2017-10-01

Our purpose was to determine whether exposure to mild intermittent hypoxia leads to a reduction in the therapeutic continuous positive airway pressure required to eliminate breathing events. Ten male participants were treated with twelve 2-min episodes of hypoxia ([Formula: see text] ≈50 mmHg) separated by 2-min intervals of normoxia in the presence of [Formula: see text] that was sustained 3 mmHg above baseline. During recovery from the last episode, the positive airway pressure was reduced in a stepwise fashion until flow limitation was evident. The participants also completed a sham protocol under normocapnic conditions, which mimicked the time frame of the intermittent hypoxia protocol. After exposure to intermittent hypoxia, the therapeutic pressure was significantly reduced (i.e., 5 cmH 2 O) without evidence of flow limitation (103.4 ± 6.3% of baseline, P = 0.5) or increases in upper airway resistance (95.6 ± 15.0% of baseline, P = 0.6). In contrast, a similar decrease in pressure was accompanied by flow limitation (77.0 ± 1.8% of baseline, P = 0.001) and an increase in upper airway resistance (167.2 ± 17.5% of baseline, P = 0.01) after the sham protocol. Consistent with the initiation of long-term facilitation of upper airway muscle activity, exposure to intermittent hypoxia reduced the therapeutic pressure required to eliminate apneic events that could improve treatment compliance. This possibility, coupled with the potentially beneficial effects of intermittent hypoxia on comorbidities linked to sleep apnea, suggests that mild intermittent hypoxia may have a multipronged therapeutic effect on sleep apnea. NEW & NOTEWORTHY Our new finding is that exposure to mild intermittent hypoxia reduced the therapeutic pressure required to treat sleep apnea. These findings are consistent with previous results, which have shown that long-term facilitation of upper muscle activity can be initiated following exposure to intermittent hypoxia in humans.

BATSE/OSSE Rapid Burst Response

National Research Council Canada - National Science Library

Matz, S. M; Grove, J. E; Johnson, W. N; Kurfess, J. D; Share, G. H; Fishman, G. J; Meegan, Charles A

1995-01-01

...) slew the OSSE detectors to burst locations determined on-board by BATSE. This enables OSSE to make sensitive searches for prompt and delayed post-burst line and continuum emission above 50 keV...

Some polarization features of solar microwave bursts

Energy Technology Data Exchange (ETDEWEB)

Uralov, A M; Nefed' ev, V P [AN SSSR, Irkutsk. Sibirskij Inst. Zemnogo Magnetizma Ionosfery i Rasprostraneniya Radiovoln

1977-01-01

Consequences of the thermal microwave burst model proposed earlier have been considered. According to the model the centimeter burst is generated at the heat propagation to the upper atmosphere. The polarization features of the burst are explained: a change of the polarization sign in a frequency range, a rapid change of the polarization sign in the development of a burst at a fixed frequency, a lack of time coincidence of the moments of the burst maximum of the polarization and of the total flux. From the model the consequences are obtained, which are still not confirmed by experiment. An ordinary-type wave prevails in the burst radiation, in the course of which the polarization degree falls on the ascending branch of bursts development. At the change of the polarization sign at the fixed frequency prior to the sign change an ordinary-type wave should be present in excess and later an extreordinary type wave.

Obstructive sleep apnea and intermittent hypoxia increase expression of dual specificity phosphatase 1.

Science.gov (United States)

Hoffmann, Michal S; Singh, Prachi; Wolk, Robert; Narkiewicz, Krzysztof; Somers, Virend K

2013-12-01

Dual specificity phosphatase 1 (DUSP1) inhibits mitogen activated protein kinase activity, and is activated by several stimuli such as sustained hypoxia, oxidative stress, and hormones. However, the effect of intermittent hypoxia is not known. The aim of this study was to evaluate the role of intermittent hypoxia on DUSP1 expression, and to validate its role in a human model of intermittent hypoxia, as seen in obstructive sleep apnea (OSA). OSA is characterized by recurrent episodes of hypoxemia/reoxygenation and is a known risk factor for cardiovascular morbidity. In-vitro studies using human coronary artery endothelial cells (HCAEC) and ex-vivo studies using white blood cells isolated from healthy and OSA subjects. Intermittent hypoxia induced DUSP1 expression in human coronary artery endothelial cells (HCAEC), and in granulocytes isolated from healthy human subjects. Functionally, DUSP1 increased the expression and activity of manganese superoxide dismutase (MnSOD) in HCAEC. Further, significant increases in DUSP1 mRNA from total blood, and in DUSP1 protein in mononuclear cells and granulocytes isolated from OSA subjects, were observed in the early morning hours after one night of intermittent hypoxemia due to untreated OSA. This early-morning OSA-induced augmentation of DUSP1 gene expression was attenuated by continuous positive airway pressure (CPAP) treatment of OSA. Intermittent hypoxia increases MnSOD activity via increased DUSP1 expression in HCAEC. Similarly, overnight intermittent hypoxemia in patients with OSA induces expression of DUSP1, which may mediate increases of MnSOD expression and activity. This may contribute significantly to neutralizing the effects of reactive oxygen species, a consequence of the intermittent hypoxemia/reperfusion elicited by OSA. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

CONDITIONED ANALYSIS OF HIGH-LATITUDE SOLAR WIND INTERMITTENCY

International Nuclear Information System (INIS)

D'Amicis, R.; Consolini, G.; Bavassano, B.; Bruno, R.

2012-01-01

The solar wind is a turbulent medium displaying intermittency. Its intermittent features have been widely documented and studied, showing how the intermittent character is different in fast and slow wind. In this paper, a statistical conditioned analysis of the solar wind intermittency for a period of high-latitude fast solar wind is presented. In particular, the intermittent features are investigated as a function of the Alfvénic degree of fluctuations at a given scale. The results show that the main contribution to solar wind intermittency is due to non-Alfvénic structures, while Alfvénic increments are found to be characterized by a smaller level of intermittency than the previous ones. Furthermore, the lifetime statistics of Alfvénic periods are discussed in terms of a multiscale texture of randomly oriented flux tubes.

Gamma Ray Bursts-Afterglows and Counterparts

Science.gov (United States)

Fishman, Gerald J

1998-01-01

Several breakthrough discoveries were made last year of x-ray, optical and radio afterglows and counterparts to gamma-ray bursts, and a redshift has been associated with at least one of these. These discoveries were made possible by the fast, accurate gamma-ray burst locations of the BeppoSAX satellite. It is now generally believed that the burst sources are at cosmological distances and that they represent the most powerful explosions in the Universe. These observations also open new possibilities for the study of early star formation, the physics of extreme conditions and perhaps even cosmology. This session will concentrate on recent x-ray, optical and radio afterglow observations of gamma-ray bursts, associated redshift measurements, and counterpart observations. Several review and theory talks will also be presented, along with a summary of the astrophysical implications of the observations. There will be additional poster contributions on observations of gamma-ray burst source locations at wavelengths other than gamma rays. Posters are also solicited that describe new observational capabilities for rapid follow-up observations of gamma-ray bursts.

Multistability and hidden attractors in an impulsive Goodwin oscillator with time delay

DEFF Research Database (Denmark)

Zhusubaliyev, Z. T.; Mosekilde, Erik; Churilov, A. N.

2015-01-01

are subject to a negative feedback regulation that is capable of modifying the intermittent bursts into more regular pulse trains. Bifurcation analysis of a hybrid model that attempts to integrate the intermittent bursting activity with a continuous hormone secretion has recently demonstrated a number...

Intermittency '93

International Nuclear Information System (INIS)

Bialas, A.

1993-01-01

The existing data definitely indicate the existence of intermittency, i.e. of self similar structures in the systems of particles created in high-energy collisions. The effect seems universal: it was found in most of the processes investigated and its measures parameters depend only weakly (if at all) on the process in question. Strong HBT effect was found, suggesting that intermittency is related to space-time structure of the pion source rather than to detailed momentum structure of the production amplitudes. There are indications that this space time structure may be fractal, but more data is needed to establish this. The theoretical explanation remains obscure: it seems that both parton cascade and hadronization play an important role. Their interrelation, however, remains a mystery. 5 figs., 19 refs

Enhancement of motor learning by focal intermittent theta burst stimulation (iTBS) of either the primary motor (M1) or somatosensory area (S1) in healthy human subjects.

Science.gov (United States)

Platz, Thomas; Adler-Wiebe, Marija; Roschka, Sybille; Lotze, Martin

2018-01-01

Motor rehabilitation after brain damage relies on motor re-learning as induced by specific training. Non-invasive brain stimulation (NIBS) can alter cortical excitability and thereby has a potential to enhance subsequent training-induced learning. Knowledge about any priming effects of NIBS on motor learning in healthy subjects can help to design targeted therapeutic applications in brain-damaged subjects. To examine whether complex motor learning in healthy subjects can be enhanced by intermittent theta burst stimulation (iTBS) to primary motor or sensory cortical areas. Eighteen young healthy subjects trained eight different arm motor tasks (arm ability training, AAT) once a day for 5 days using their left non-dominant arm. Except for day 1 (baseline), training was performed after applying an excitatory form of repetitive transcranial magnetic stimulation (iTBS) to either (I) right M1 or (II) S1, or (III) sham stimulation to the right M1. Subjects were randomly assigned to conditions I, II, or III. A principal component analysis of the motor behaviour data suggested eight independent motor abilities corresponding to the 8 trained tasks. AAT induced substantial motor learning across abilities with generalisation to a non-trained test of finger dexterity (Nine-Hole-Peg-Test, NHPT). Participants receiving iTBS (to either M1 or S1) showed better performance with the AAT tasks over the period of training compared to sham stimulation as well as a bigger improvement with the generalisation task (NHPT) for the trained left hand after training completion. Priming with an excitatory repetitive transcranial magnetic stimulation as iTBS of either M1 or S1 can enhance motor learning across different sensorimotor abilities.

SGR J1550-5418 BURSTS DETECTED WITH THE FERMI GAMMA-RAY BURST MONITOR DURING ITS MOST PROLIFIC ACTIVITY

Energy Technology Data Exchange (ETDEWEB)

Van der Horst, A. J.; Finger, M. H. [Universities Space Research Association, NSSTC, Huntsville, AL 35805 (United States); Kouveliotou, C. [Space Science Office, VP62, NASA/Marshall Space Flight Center, Huntsville, AL 35812 (United States); Gorgone, N. M. [Connecticut College, New London, CT 06320 (United States); Kaneko, Y.; Goegues, E.; Lin, L. [Sabanc Latin-Small-Letter-Dotless-I University, Orhanl Latin-Small-Letter-Dotless-I -Tuzla, Istanbul 34956 (Turkey); Baring, M. G. [Department of Physics and Astronomy, Rice University, MS-108, P.O. Box 1892, Houston, TX 77251 (United States); Guiriec, S.; Bhat, P. N.; Chaplin, V. L.; Goldstein, A. [University of Alabama, Huntsville, CSPAR, Huntsville, AL 35805 (United States); Granot, J. [Racah Institute of Physics, Hebrew University, Jerusalem 91904 (Israel); Watts, A. L. [Astronomical Institute ' Anton Pannekoek' , University of Amsterdam, Postbus 94249, 1090 GE Amsterdam (Netherlands); Bissaldi, E.; Gruber, D. [Max Planck Institute for Extraterrestrial Physics, Giessenbachstrasse, Postfach 1312, 85748 Garching (Germany); Gehrels, N.; Harding, A. K. [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Gibby, M. H.; Giles, M. M., E-mail: A.J.VanDerHorst@uva.nl [Jacobs Technology, Inc., Huntsville, AL (United States); and others

2012-04-20

We have performed detailed temporal and time-integrated spectral analysis of 286 bursts from SGR J1550-5418 detected with the Fermi Gamma-ray Burst Monitor (GBM) in 2009 January, resulting in the largest uniform sample of temporal and spectral properties of SGR J1550-5418 bursts. We have used the combination of broadband and high time-resolution data provided with GBM to perform statistical studies for the source properties. We determine the durations, emission times, duty cycles, and rise times for all bursts, and find that they are typical of SGR bursts. We explore various models in our spectral analysis, and conclude that the spectra of SGR J1550-5418 bursts in the 8-200 keV band are equally well described by optically thin thermal bremsstrahlung (OTTB), a power law (PL) with an exponential cutoff (Comptonized model), and two blackbody (BB) functions (BB+BB). In the spectral fits with the Comptonized model, we find a mean PL index of -0.92, close to the OTTB index of -1. We show that there is an anti-correlation between the Comptonized E{sub peak} and the burst fluence and average flux. For the BB+BB fits, we find that the fluences and emission areas of the two BB functions are correlated. The low-temperature BB has an emission area comparable to the neutron star surface area, independent of the temperature, while the high-temperature BB has a much smaller area and shows an anti-correlation between emission area and temperature. We compare the properties of these bursts with bursts observed from other SGR sources during extreme activations, and discuss the implications of our results in the context of magnetar burst models.

THE FIVE YEAR FERMI/GBM MAGNETAR BURST CATALOG

Energy Technology Data Exchange (ETDEWEB)

Collazzi, A. C. [SciTec, Inc., 100 Wall Street, Princeton, NJ 08540 (United States); Kouveliotou, C.; Horst, A. J. van der; Younes, G. A. [Department of Physics, The George Washington University, 725 21st Street NW, Washington, DC 20052 (United States); Kaneko, Y.; Göğüş, E. [Sabancı University, Orhanlı-Tuzla, İstanbul 34956 (Turkey); Lin, L. [François Arago Centre, APC, 10 rue Alice Domon et Léonie Duquet, F-75205 Paris (France); Granot, J. [Department of Natural Sciences, The Open University of Israel, 1 University Road, P.O. Box 808, Raanana 43537 (Israel); Finger, M. H. [Universities Space Research Association, NSSTC, 320 Sparkman Drive, Huntsville, AL 35805 (United States); Chaplin, V. L. [School of Medicine, Vanderbilt University, 1161 21st Avenue S, Nashville, TN 37232 (United States); Huppenkothen, D. [Center for Data Science, New York University, 726 Broadway, 7th Floor, New York, NY 10003 (United States); Watts, A. L. [Anton Pannekoek Institute, University of Amsterdam, Postbus 94249, 1090 GE Amsterdam (Netherlands); Kienlin, A. von [Max-Planck-Institut für extraterrestrische Physik, Giessenbachstrasse 1, D-85748 Garching (Germany); Baring, M. G. [Department of Physics and Astronomy, Rice University, MS-108, P.O. Box 1892, Houston, TX 77251 (United States); Gruber, D. [Planetarium Südtirol, Gummer 5, I-39053 Karneid (Italy); Bhat, P. N. [CSPAR, University of Alabama in Huntsville, 320 Sparkman Drive, Huntsville, AL 35899 (United States); Gibby, M. H., E-mail: acollazzi@scitec.com [Jacobs Technology, Inc., Huntsville, AL (United States); and others

2015-05-15

Since launch in 2008, the Fermi Gamma-ray Burst Monitor (GBM) has detected many hundreds of bursts from magnetar sources. While the vast majority of these bursts have been attributed to several known magnetars, there is also a small sample of magnetar-like bursts of unknown origin. Here, we present the Fermi/GBM magnetar catalog, providing the results of the temporal and spectral analyses of 440 magnetar bursts with high temporal and spectral resolution. This catalog covers the first five years of GBM magnetar observations, from 2008 July to 2013 June. We provide durations, spectral parameters for various models, fluences, and peak fluxes for all the bursts, as well as a detailed temporal analysis for SGR J1550–5418 bursts. Finally, we suggest that some of the bursts of unknown origin are associated with the newly discovered magnetar 3XMM J185246.6+0033.7.

Persistent 1.5s oscillations superimposed to a solar burst observed at two mm-wavelengths

International Nuclear Information System (INIS)

Zodi, A.M.; Kaufmann, P.; Zirin, H.

1983-05-01

Long-enduring quasi-periodic oscillations (1.5s) superimposed to a solar burst were by the first time observed simultaneously at two different mm-wayelengths (22 GHz and 44 GHz). The oscillations were present throughout the burst duration (about 10 min), and were delayed at 44 GHz with respect to 22 GHz by 0.3s. The relative amplitude of the oscillation was of about 20 percent at 44 GHz and of about 5 percent at 22 GHz. Interferometer measurements at 10.6 GHz indicated the burst source stable within 1 arcsec. HeD3 line flare indicated two persistent small spots separated by about 10 arcsec. The 22/44 GHz burst position has good correspondence with the HeD3 spots' location. The oscillations display features which appear to distinguish them from ultrafast time structures found in other bursts. One possible interpretation was suggested by assuming a modulation of the gyrosynchrotron emission of trapped electrons by a variable magnetic field on a double burst source, optically thin at 44 GHz and with optical thickness > or equivalent 0.3 at 22 GHz. (Author) [pt

Hierarchic Analysis Method to Evaluate Rock Burst Risk

Directory of Open Access Journals (Sweden)

Ming Ji

2015-01-01

Full Text Available In order to reasonably evaluate the risk of rock bursts in mines, the factors impacting rock bursts and the existing grading criterion on the risk of rock bursts were studied. By building a model of hierarchic analysis method, the natural factors, technology factors, and management factors that influence rock bursts were analyzed and researched, which determined the degree of each factor’s influence (i.e., weight and comprehensive index. Then the grade of rock burst risk was assessed. The results showed that the assessment level generated by the model accurately reflected the actual risk degree of rock bursts in mines. The model improved the maneuverability and practicability of existing evaluation criteria and also enhanced the accuracy and science of rock burst risk assessment.

Synchronous bursts on scale-free neuronal networks with attractive and repulsive coupling.

Directory of Open Access Journals (Sweden)

Qingyun Wang

Full Text Available This paper investigates the dependence of synchronization transitions of bursting oscillations on the information transmission delay over scale-free neuronal networks with attractive and repulsive coupling. It is shown that for both types of coupling, the delay always plays a subtle role in either promoting or impairing synchronization. In particular, depending on the inherent oscillation period of individual neurons, regions of irregular and regular propagating excitatory fronts appear intermittently as the delay increases. These delay-induced synchronization transitions are manifested as well-expressed minima in the measure for spatiotemporal synchrony. For attractive coupling, the minima appear at every integer multiple of the average oscillation period, while for the repulsive coupling, they appear at every odd multiple of the half of the average oscillation period. The obtained results are robust to the variations of the dynamics of individual neurons, the system size, and the neuronal firing type. Hence, they can be used to characterize attractively or repulsively coupled scale-free neuronal networks with delays.

Observation of gamma-ray bursts with GINGA

International Nuclear Information System (INIS)

Murakami, Toshio; Fujii, Masami; Nishimura, Jun

1989-01-01

Gamma-ray Burst Detector System (GBD) on board the scientific satellite 'GINGA' which was launched on Feb. 5, 1987, was realized as an international cooperation between ISAS and LANL. It has recorded more than 40 Gamma-Ray Burst candidates during 20 months observation. Although many observational evidences were accumulated in past 20 years after the discovery of gamma-ray burst by LANL scientists, there are not enough evidence to determine the origin and the production mechanism of the gamma-ray burst. GBD consists of a proportional counter and a NaI scintillation counter so that it became possible to observe energy spectrum of the gamma-ray burst with high energy resolution over wide range of energy (1.5-380 keV) together with high time resolution. As the result of observation, the following facts are obtained: (1) A large fraction of observed gamma-ray bursts has a long X-ray tail after the harder part of gamma-ray emission has terminated. (2) Clear spectral absorption features with harmonic in energy was observed in some of the energy spectrum of gamma-ray bursts. These evidences support the hypothesis that the strongly magnetized neutron star is the origin of gamma-ray burst. (author)

Swift Burst Alert Telescope (BAT) Instrument Response

International Nuclear Information System (INIS)

Parsons, A.; Barthelmy, S.; Cummings, J.; Gehrels, N.; Hullinger, D.; Krimm, H.; Markwardt, C.; Tueller, J.; Fenimore, E.; Palmer, D.; Sato, G.; Takahashi, T.; Nakazawa, K.; Okada, Y.; Takahashi, H.; Suzuki, M.; Tashiro, M.

2004-01-01

The Burst Alert Telescope (BAT), a large coded aperture instrument with a wide field-of-view (FOV), provides the gamma-ray burst triggers and locations for the Swift Gamma-Ray Burst Explorer. In addition to providing this imaging information, BAT will perform a 15 keV - 150 keV all-sky hard x-ray survey based on the serendipitous pointings resulting from the study of gamma-ray bursts, and will also monitor the sky for transient hard x-ray sources. For BAT to provide spectral and photometric information for the gamma-ray bursts, the transient sources and the all-sky survey, the BAT instrument response must be determined to an increasingly greater accuracy. This paper describes the spectral models and the ground calibration experiments used to determine the BAT response to an accuracy suitable for gamma-ray burst studies

Mechanism of Rock Burst Occurrence in Specially Thick Coal Seam with Rock Parting

Science.gov (United States)

Wang, Jian-chao; Jiang, Fu-xing; Meng, Xiang-jun; Wang, Xu-you; Zhu, Si-tao; Feng, Yu

2016-05-01

Specially thick coal seam with complex construction, such as rock parting and alternative soft and hard coal, is called specially thick coal seam with rock parting (STCSRP), which easily leads to rock burst during mining. Based on the stress distribution of rock parting zone, this study investigated the mechanism, engineering discriminant conditions, prevention methods, and risk evaluation method of rock burst occurrence in STCSRP through setting up a mechanical model. The main conclusions of this study are as follows. (1) When the mining face moves closer to the rock parting zone, the original non-uniform stress of the rock parting zone and the advancing stress of the mining face are combined to intensify gradually the shearing action of coal near the mining face. When the shearing action reaches a certain degree, rock burst easily occurs near the mining face. (2) Rock burst occurrence in STCSRP is positively associated with mining depth, advancing stress concentration factor of the mining face, thickness of rock parting, bursting liability of coal, thickness ratio of rock parting to coal seam, and difference of elastic modulus between rock parting and coal, whereas negatively associated with shear strength. (3) Technologies of large-diameter drilling, coal seam water injection, and deep hole blasting can reduce advancing stress concentration factor, thickness of rock parting, and difference of elastic modulus between rock parting and coal to lower the risk of rock burst in STCSRP. (4) The research result was applied to evaluate and control the risk of rock burst occurrence in STCSRP.

Pressure Autoregulation Measurement Techniques in Adult Traumatic Brain Injury, Part I: A Scoping Review of Intermittent/Semi-Intermittent Methods.

Science.gov (United States)

Zeiler, Frederick A; Donnelly, Joseph; Calviello, Leanne; Menon, David K; Smielewski, Peter; Czosnyka, Marek

2017-12-01

The purpose of this study was to perform a systematic, scoping review of commonly described intermittent/semi-intermittent autoregulation measurement techniques in adult traumatic brain injury (TBI). Nine separate systematic reviews were conducted for each intermittent technique: computed tomographic perfusion (CTP)/Xenon-CT (Xe-CT), positron emission tomography (PET), magnetic resonance imaging (MRI), arteriovenous difference in oxygen (AVDO 2 ) technique, thigh cuff deflation technique (TCDT), transient hyperemic response test (THRT), orthostatic hypotension test (OHT), mean flow index (Mx), and transfer function autoregulation index (TF-ARI). MEDLINE ® , BIOSIS, EMBASE, Global Health, Scopus, Cochrane Library (inception to December 2016), and reference lists of relevant articles were searched. A two tier filter of references was conducted. The total number of articles utilizing each of the nine searched techniques for intermittent/semi-intermittent autoregulation techniques in adult TBI were: CTP/Xe-CT (10), PET (6), MRI (0), AVDO 2 (10), ARI-based TCDT (9), THRT (6), OHT (3), Mx (17), and TF-ARI (6). The premise behind all of the intermittent techniques is manipulation of systemic blood pressure/blood volume via either chemical (such as vasopressors) or mechanical (such as thigh cuffs or carotid compression) means. Exceptionally, Mx and TF-ARI are based on spontaneous fluctuations of cerebral perfusion pressure (CPP) or mean arterial pressure (MAP). The method for assessing the cerebral circulation during these manipulations varies, with both imaging-based techniques and TCD utilized. Despite the limited literature for intermittent/semi-intermittent techniques in adult TBI (minus Mx), it is important to acknowledge the availability of such tests. They have provided fundamental insight into human autoregulatory capacity, leading to the development of continuous and more commonly applied techniques in the intensive care unit (ICU). Numerous methods of

Dark gamma-ray bursts

Science.gov (United States)

Brdar, Vedran; Kopp, Joachim; Liu, Jia

2017-03-01

Many theories of dark matter (DM) predict that DM particles can be captured by stars via scattering on ordinary matter. They subsequently condense into a DM core close to the center of the star and eventually annihilate. In this work, we trace DM capture and annihilation rates throughout the life of a massive star and show that this evolution culminates in an intense annihilation burst coincident with the death of the star in a core collapse supernova. The reason is that, along with the stellar interior, also its DM core heats up and contracts, so that the DM density increases rapidly during the final stages of stellar evolution. We argue that, counterintuitively, the annihilation burst is more intense if DM annihilation is a p -wave process than for s -wave annihilation because in the former case, more DM particles survive until the supernova. If among the DM annihilation products are particles like dark photons that can escape the exploding star and decay to standard model particles later, the annihilation burst results in a flash of gamma rays accompanying the supernova. For a galactic supernova, this "dark gamma-ray burst" may be observable in the Čerenkov Telescope Array.

X-ray observations of the 5 March 1979. gamma. -burst field

Energy Technology Data Exchange (ETDEWEB)

Helfand, D J; Long, K S [Columbia Univ., New York (USA). Columbia Astrophysics Lab.

1979-12-06

On 5 March 1979 an extremely intense burst of hard X-rays and ..gamma..-rays was recorded by the nine interplanetary spacecraft of the burst sensor network and localised by time-of-flight determinations to a position coincident with the supernova remnant N49 in the Large Magellanic Cloud. Several times, both before and after the ..gamma..-ray event, this region of the sky was observed with the soft X-ray imaging instruments aboard the Einstein Observatory. Coupled with optical plate material, the soft x-ray data are used here to place severe constraints on models for the origin of this remarkable transient phenomenon.

BURST AND OUTBURST CHARACTERISTICS OF MAGNETAR 4U 0142+61

Energy Technology Data Exchange (ETDEWEB)

Göğüş, Ersin; Chakraborty, Manoneeta; Kaneko, Yuki [Sabancı University, Orhanlı-Tuzla, İstanbul 34956 (Turkey); Lin, Lin [Department of Astronomy, Beijing Normal University, Beijing 100875 (China); Roberts, Oliver J. [School of Physics, University College Dublin, Stillorgan Road, Belfield, Dublin 4 (Ireland); Gill, Ramandeep; Granot, Jonathan [Department of Natural Sciences, The Open University of Israel, 1 University Road, P.O. Box 808, Ranana 43537 (Israel); Horst, Alexander J. van der; Kouveliotou, Chryssa; Younes, George [Department of Physics, The George Washington University, Washington, DC 20052 (United States); Watts, Anna L. [Anton Pannekoek Institute for Astronomy, University of Amsterdam, Postbus 94249, NL-1090 GE Amsterdam (Netherlands); Baring, Matthew [Department of Physics and Astronomy, Rice University, MS-108, P.O. Box 1892, Houston, TX 77251 (United States); Huppenkothen, Daniela [Center for Data Science, New York University, 726 Broadway, 7th Floor, NY 10003 (United States)

2017-01-20

We have compiled the most comprehensive burst sample from magnetar 4U 0142+61, comprising 27 bursts from its three burst-active episodes in 2011, 2012 and the latest one in 2015 observed with Swift /Burst Alert Telescope and Fermi /Gamma-ray Burst Monitor. Bursts from 4U 0142+61 morphologically resemble typical short bursts from other magnetars. However, 4U 0142+61 bursts are less energetic compared to the bulk of magnetar bursts. We uncovered an extended tail emission following a burst on 2015 February 28, with a thermal nature, cooling over a timescale of several minutes. During this tail emission, we also uncovered pulse peak phase aligned X-ray bursts, which could originate from the same underlying mechanism as that of the extended burst tail, or an associated and spatially coincident but different mechanism.

A search for fast radio bursts associated with gamma-ray bursts

International Nuclear Information System (INIS)

Palaniswamy, Divya; Wayth, Randall B.; Trott, Cathryn M.; Tingay, Steven J.; Reynolds, Cormac; McCallum, Jamie N.

2014-01-01

The detection of seven fast radio bursts (FRBs) has recently been reported. FRBs are short duration (∼1 ms), highly dispersed radio pulses from astronomical sources. The physical interpretation for the FRBs remains unclear but is thought to involve highly compact objects at cosmological distance. It has been suggested that a fraction of FRBs could be physically associated with gamma-ray bursts (GRBs). Recent radio observations of GRBs have reported the detection of two highly dispersed short duration radio pulses using a 12 m radio telescope at 1.4 GHz. Motivated by this result, we have performed a systematic and sensitive search for FRBs associated with GRBs. We have observed five GRBs at 2.3 GHz using a 26 m radio telescope located at the Mount Pleasant Radio Observatory, Hobart. The radio telescope was automated to rapidly respond to Gamma-ray Coordination Network notifications from the Swift satellite and slew to the GRB position within ∼140 s. The data were searched for pulses up to 5000 pc cm –3 in dispersion measure and pulse widths ranging from 640 μs to 25.60 ms. We did not detect any events ≥6σ. An in depth statistical analysis of our data shows that events detected above 5σ are consistent with thermal noise fluctuations only. A joint analysis of our data with previous experiments shows that previously claimed detections of FRBs from GRBs are unlikely to be astrophysical. Our results are in line with the lack of consistency noted between the recently presented FRB event rates and GRB event rates.

Bursting synchronization in clustered neuronal networks

International Nuclear Information System (INIS)

Yu Hai-Tao; Wang Jiang; Deng Bin; Wei Xi-Le

2013-01-01

Neuronal networks in the brain exhibit the modular (clustered) property, i.e., they are composed of certain subnetworks with differential internal and external connectivity. We investigate bursting synchronization in a clustered neuronal network. A transition to mutual-phase synchronization takes place on the bursting time scale of coupled neurons, while on the spiking time scale, they behave asynchronously. This synchronization transition can be induced by the variations of inter- and intracoupling strengths, as well as the probability of random links between different subnetworks. Considering that some pathological conditions are related with the synchronization of bursting neurons in the brain, we analyze the control of bursting synchronization by using a time-periodic external signal in the clustered neuronal network. Simulation results show a frequency locking tongue in the driving parameter plane, where bursting synchronization is maintained, even in the presence of external driving. Hence, effective synchronization suppression can be realized with the driving parameters outside the frequency locking region. (interdisciplinary physics and related areas of science and technology)

Optimal intermittent search strategies

International Nuclear Information System (INIS)

Rojo, F; Budde, C E; Wio, H S

2009-01-01

We study the search kinetics of a single fixed target by a set of searchers performing an intermittent random walk, jumping between different internal states. Exploiting concepts of multi-state and continuous-time random walks we have calculated the survival probability of a target up to time t, and have 'optimized' (minimized) it with regard to the transition probability among internal states. Our model shows that intermittent strategies always improve target detection, even for simple diffusion states of motion

Self-regulation of turbulence bursts and transport barriers

International Nuclear Information System (INIS)

Floriani, E; Ciraolo, G; Ghendrih, Ph; Sarazin, Y; Lima, R

2013-01-01

The interplay between turbulent bursts and transport barriers is analyzed with a simplified model of interchange turbulence in magnetically confined plasmas. The turbulent bursts spread into the transport barriers and, depending on the competing magnitude of the burst and stopping capability of the barrier, can burn through. Simulations of two models of transport barriers are presented: a hard barrier where interchange turbulence modes are stable in a prescribed region and a soft barrier with external plasma biasing. The response of the transport barriers to the non-linear perturbations of the turbulent bursts, addressed in a predator–prey approach, indicates that the barriers monitor an amplification factor of the turbulent bursts, with amplification smaller than one for most bursts and, in some cases, amplification factors that can significantly exceed unity. The weak barriers in corrugated profiles and magnetic structures, as well as the standard barriers, are characterized by these transmission properties, which then regulate the turbulent burst transport properties. The interplays of barriers and turbulent bursts are modeled as competing stochastic processes. For different classes of the probability density function (PDF) of these processes, one can predict the heavy tail properties of the bursts downstream from the barrier, either exponential for a leaky barrier, or with power laws for a tight barrier. The intrinsic probing of the transport barriers by the turbulent bursts thus gives access to the properties of the barriers. The main stochastic variables are the barrier width and the spreading distance of the turbulent bursts within the barrier, together with their level of correlation. One finds that in the case of a barrier with volumetric losses, such as radiation or particle losses as addressed in our present simulations, the stochastic model predicts a leaky behavior with an exponential PDF of escaping turbulent bursts in agreement with the simulation

The γ-ray burst-detection system of SPI

International Nuclear Information System (INIS)

Lichti, G.G.; Georgii, R.; Kienlin, A. von; Schoenfelder, V.; Wunderer, C.; Jung, H.-J.; Hurley, K.

2000-01-01

The determination of precise locations of γ-ray bursts is a crucial task of γ-ray astronomy. Although γ-ray burst locations can be obtained nowadays from single experiments (BATSE, COMPTEL, BeppoSax) the location of bursts via triangulation using the interplanetary network is still important because not all bursts will be located precisely enough by these single instruments. In order to get location accuracies down to arcseconds via triangulation one needs long baselines. At the beginning of the next decade several spacecrafts which explore the outer planetary system (the Mars-Surveyor-2001 Orbiter and probably Ulysses) will carry γ-ray burst instruments. INTEGRAL as a near-earth spacecraft is the ideal counterpart for these satellites. The massive anticoincidence shield of the INTEGRAL-spectrometer SPI allows the measurement of γ-ray bursts with a high sensitivity. Estimations have shown that with SPI some hundred γ-ray bursts per year on the 5σ level can be measured. This is equivalent to the BATSE sensitivity. We describe the γ-ray burst-detection system of SPI, present its technical features and assess the scientific capabilities

Mouse Intermittent Hypoxia Mimicking Apnea of Prematurity: Effects on Myelinogenesis and Axonal Maturation

Science.gov (United States)

CAI, JUN; TUONG, CHI MINH; ZHANG, YIPING; SHIELDS, CHRISTOPHER B.; GUO, GANG; FU, HUI; GOZAL, DAVID

2014-01-01

Premature babies are at high risk for both infantile apnea and long-term neurobehavioral deficits. Recent studies suggest that diffuse structural changes in brain white matter are a positive predictor of poor cognitive outcomes. Since oligodendrocyte maturation, myelination, axon development and synapse formation mainly occur in the 3rd trimester of gestation and 1st postnatal year, infantile apnea could lead to and/or exaggerate white matter impairments in preterm neonates. Therefore, we investigated oligodendroglia and axon development in a neonatal mouse model of intermittent hypoxia between postnatal days 2 to 10. During critical phases of central nervous system development, intermittent hypoxia induced hypomyelination in the corpus callosum, striatum, fornix and cerebellum, but not the pons or spinal cord. Intermittent hypoxia-elicited alterations in myelin-forming processes were reflected by decreased expression of myelin proteins, including MBP, PLP, MAG and CNPase, possibly due to arrested maturation of oligodendrocytes. Ultra-structural abnormalities were apparent in the myelin sheath and axon. Immature oligodendrocytes were more vulnerable to neonatal intermittent hypoxia exposures than developing axons, suggesting that hypomyelination may contribute, at least partially, to axonal deficits. Insufficient neurofilament synthesis with anomalous components of neurofilament subunits, β-tubulin and MAP2 isoforms indicated immaturity of axons in intermittent hypoxia-exposed mouse brains. In addition, down-regulation of Synapsin I, Synaptophysin and Gap-43 phosphorylation suggested a potential stunt in axonogenesis and synaptogenesis. The region-selective and complex impairment in brain white matter induced by intermittent hypoxia was further associated with electrophysiological changes that may underlie long-term neurobehavioral sequelae. PMID:21953180

Probability distribution functions for intermittent scrape-off layer plasma fluctuations

Science.gov (United States)

Theodorsen, A.; Garcia, O. E.

2018-03-01

A stochastic model for intermittent fluctuations in the scrape-off layer of magnetically confined plasmas has been constructed based on a super-position of uncorrelated pulses arriving according to a Poisson process. In the most common applications of the model, the pulse amplitudes are assumed exponentially distributed, supported by conditional averaging of large-amplitude fluctuations in experimental measurement data. This basic assumption has two potential limitations. First, statistical analysis of measurement data using conditional averaging only reveals the tail of the amplitude distribution to be exponentially distributed. Second, exponentially distributed amplitudes leads to a positive definite signal which cannot capture fluctuations in for example electric potential and radial velocity. Assuming pulse amplitudes which are not positive definite often make finding a closed form for the probability density function (PDF) difficult, even if the characteristic function remains relatively simple. Thus estimating model parameters requires an approach based on the characteristic function, not the PDF. In this contribution, the effect of changing the amplitude distribution on the moments, PDF and characteristic function of the process is investigated and a parameter estimation method using the empirical characteristic function is presented and tested on synthetically generated data. This proves valuable for describing intermittent fluctuations of all plasma parameters in the boundary region of magnetized plasmas.

The protracted demise of medical technology. The case of intermittent positive pressure breathing.

Science.gov (United States)

Duffy, S Q; Farley, D E

1992-08-01

In this study, the effects of hospital, staff, and patient characteristics on the rates of use and abandonment of an outmoded medical technology, intermittent positive pressure breathing (IPPB) are analyzed. The study focuses specifically on the use of IPPB to treat inpatients with chronic obstructive pulmonary disease in a national sample of more than 500 community hospitals from 1980 to 1987. Cross-sectionally, hospitals with shorter case-mix-adjusted lengths of stay, private nonprofit or investor-owned hospitals, and hospitals located outside of the north central United States were more likely to abandon IPPB by 1980. Teaching status, location, ownership, volume, and source of payment all appeared to affect rates of IPPB use in 1980. The longitudinal analysis examines both the probability a hospital abandoned IPPB and declines in rates of IPPB use over the study period, conditioned on the availability of IPPB in 1980. The results show that changes in the characteristics of hospitals, patients, and physicians all help to explain variations in the abandonment of IPPB. These findings contrast with previous studies of technological change, which find hospital size to be the most important variable. Size is important in explaining the rate of use in 1980, but it has no effect on the rate of decline in use or abandonment after 1980. In general, the analysis demonstrates that a combination of factors, economic incentives as well as information, contribute to the abandonment of outmoded medical technologies. Given the surprisingly long time periods required for this process to occur, the analysis underscores the need to strengthen financial incentives that encourage appropriate medical decisions and to disseminate information about the efficacy of specific procedures more widely and effectively.

Frequency of fast, narrow γ-ray bursts

International Nuclear Information System (INIS)

Norris, J.P.; Maryland Univ., College Park; Cline, T.L.; Desai, U.D.; Teegarden, B.J.

1984-01-01

The paper describes the existence of two γ-ray burst populations detected by the ISEE-3 experiment. Data from the distribution of 123 Venera 13 and 14 events (60 detected by both spacecraft) also suggests two γ-ray burst populations in each experiment sample, the domains separated with a minimum near 1 or 2 s. The authors point out that the results of the Goddard ISEE-3 γ-ray burst spectrometer actually enhance the appearance of two burst populations suggested in the Venera data. (author)

Possible galactic origin of. gamma. -ray bursts

Energy Technology Data Exchange (ETDEWEB)

Manchanda, R K; Ramsden, D [Southampton Univ. (UK). Dept. of Physics

1977-03-31

It is stated that extragalactic models for the origin of non-solar ..gamma..-ray bursts include supernova bursts in remote galaxies, and the collapse of the cores of active stars, whilst galactic models are based on flare stars, thermonuclear explosions in neutron stars and the sudden accretion of cometary gas on to neutron stars. The acceptability of any of these models may be tested by the observed size spectrum of the ..gamma..-ray bursts. The extragalactic models predict a power law spectrum with number index -1.5, whilst for the galactic models the number index will be -1. Experimental data on ..gamma..-ray bursts is, however, still meagre, and so far only 44 confirmed events have been recorded by satellite-borne instruments. The number spectrum of the observed ..gamma..-ray bursts indicates that the observed distribution for events with an energy < 10/sup -4/ erg/cm/sup 2/ is flat; this makes the choice of any model completely arbitrary. An analysis of the observed ..gamma..-ray events is here presented that suggests very interesting possibilities for their origin. There appears to be a preferred mean energy for ..gamma..-ray bursts; some 90% of the recorded events show a mean energy between 5 x 10/sup -5/ and 5 x 10/sup -4/ erg/cm/sup 2/, contrary to the predicted characteristics of the number spectrum of various models. A remarkable similarity is found between the distribution of ..gamma..-ray bursts and that of supernova remnants, suggesting a genetic relationship between the two and the galactic origin of the ..gamma..-ray bursts, and the burst source could be identified with completely run down neutron stars, formed during supernova explosions.

Spectral degeneracy and escape dynamics for intermittent maps with a hole

International Nuclear Information System (INIS)

Froyland, Gary; Stancevic, Ognjen; Murray, Rua

2011-01-01

We study intermittent maps from the point of view of metastability. Small neighbourhoods of an intermittent fixed point and their complements form pairs of almost-invariant sets. Treating the small neighbourhood as a hole, we first show that the absolutely continuous conditional invariant measures (ACCIMs) converge to the ACIM as the length of the small neighbourhood shrinks to zero. We then quantify how the escape dynamics from these almost-invariant sets are connected with the second eigenfunctions of Perron–Frobenius (transfer) operators when a small perturbation is applied near the intermittent fixed point. In particular, we describe precisely the scaling of the second eigenvalue with the perturbation size, provide upper and lower bounds and demonstrate L 1 convergence of the positive part of the second eigenfunction to the ACIM as the perturbation goes to zero. This perturbation and associated eigenvalue scalings and convergence results are all compatible with Ulam's method and provide a formal explanation for the numerical behaviour of Ulam's method in this nonuniformly hyperbolic setting. The main results of the paper are illustrated with numerical computations

Intermittency in {sup 197}Au fragmentation

Energy Technology Data Exchange (ETDEWEB)

Dabrowska, A; Holynski, R; Olszewski, A; Szarska, M; Wilczynska, B; Wolter, W; Wosiek, B [Institute of Nuclear Physics, Cracow (Poland); Cherry, M L; Deines-Jones, P; Jones, W V; Sengupta, K; Wefel, B [Louisiana State Univ., Baton Rouge, LA (United States). Dept. of Physics and Astronomy; Waddington, C J [Minnesota Univ., Minneapolis, MN (United States). School of Physics and Astronomy; Pozharova, E A; Skorodko, T Yu [Inst. of Theoretical and Experimental Physics, Moscow (Russian Federation); KLMM Collaboration

1995-07-01

The concept of factorial moments was applied to an analysis of the dynamical fluctuations in the charge distributions of the fragments emitted from gold nuclei with energies 10.6 and < 1.0 GeV/n interacting with emulsion nuclei. Clear evidence for intermittent fluctuations has been found in an analysis using all the particles released from the gold projectile, with a stronger effect observed below 1 GeV/n than at 10.6 GeV/n. For the full data sets, however, the intermittency effect was found to be very sensitive to the singly charged particles, and neglecting these particles strongly reduces the intermittency signal. When the analysis is restricted to the multiply charged fragments, an intermittency effect is revealed only for multifragmentation events, although one that is enhanced as compared to the analysis of all, singly and multiply charged, particles. The properties of the anomalous fractal dimensions suggest a sequential decay mechanism, rather than the existence of possible critical behaviour in the process of nuclear fragmentation. The likely influence of the charge conservation effects and the finite size of decaying systems on the observed intermittency signals was pointed out. (author). 37 refs, 9 figs, 5 tabs.

Prediction of CMEs and Type II Bursts from Sun to Earth

Science.gov (United States)

Cairns, I. H.; Schmidt, J. M.; Gopalswamy, N.; van der Holst, B.

2017-12-01

Most major space weather events are due to fast CMEs and their shocks interacting with Earth's magnetosphere. SImilarly, type II solar radio bursts are well-known signatures of CMEs and their shocks moving through the corona and solar wind. The properties of the space weather events and the type II radio bursts depend sensitively on the CME velocity, shape, and evolution as functions of position and time, as well as on the magnetic field vector in the coronal and solar wind plasma, downstream of the CME shock, and inside the CME. We report simulations of CMEs and type II bursts from the Sun to Earth with the Space Weather Modelling Framework (2015 and 2016 versions), set up carefully using relevant data, and a kinetic radio emission theory. Excellent agreement between observations, simulations, and theory are found for the coronal (metric) type II burst of 7 September 2014 and associated CME, including the lack of radio emission in the solar wind beyond about 10 solar radii. Similarly, simulation of a CME and type II burst from the Sun to 1 AU over the period 29 November - 1 December 2013 yield excellent agreement for the radio burst from 10 MHz to 30 kHz for STEREO A and B and Wind, arrival of the CME at STEREO A within 1 hour reported time, deceleration of the CME in agreement with the Gopalswamy et al. [2011] observational analyses, and Bz rotations at STEREO A from upstream of the CME shock to within the CME. These results provide strong support for the type II theory and also that the Space WeatherModeling Framework can accurately predict the properties and evolution of CMEs and the interplanetary magnetic field and plasma from the Sun to 1 AU when sufficiently carefully initialized.

Throughput Estimation Method in Burst ACK Scheme for Optimizing Frame Size and Burst Frame Number Appropriate to SNR-Related Error Rate

Science.gov (United States)

Ohteru, Shoko; Kishine, Keiji

The Burst ACK scheme enhances effective throughput by reducing ACK overhead when a transmitter sends sequentially multiple data frames to a destination. IEEE 802.11e is one such example. The size of the data frame body and the number of burst data frames are important burst transmission parameters that affect throughput. The larger the burst transmission parameters are, the better the throughput under error-free conditions becomes. However, large data frame could reduce throughput under error-prone conditions caused by signal-to-noise ratio (SNR) deterioration. If the throughput can be calculated from the burst transmission parameters and error rate, the appropriate ranges of the burst transmission parameters could be narrowed down, and the necessary buffer size for storing transmit data or received data temporarily could be estimated. In this paper, we present a method that features a simple algorithm for estimating the effective throughput from the burst transmission parameters and error rate. The calculated throughput values agree well with the measured ones for actual wireless boards based on the IEEE 802.11-based original MAC protocol. We also calculate throughput values for larger values of the burst transmission parameters outside the assignable values of the wireless boards and find the appropriate values of the burst transmission parameters.

Optimal intermittent search strategies

Energy Technology Data Exchange (ETDEWEB)

Rojo, F; Budde, C E [FaMAF, Universidad Nacional de Cordoba, Ciudad Universitaria, X5000HUA Cordoba (Argentina); Wio, H S [Instituto de Fisica de Cantabria, Universidad de Cantabria and CSIC E-39005 Santander (Spain)

2009-03-27

We study the search kinetics of a single fixed target by a set of searchers performing an intermittent random walk, jumping between different internal states. Exploiting concepts of multi-state and continuous-time random walks we have calculated the survival probability of a target up to time t, and have 'optimized' (minimized) it with regard to the transition probability among internal states. Our model shows that intermittent strategies always improve target detection, even for simple diffusion states of motion.

Optimal Codes for the Burst Erasure Channel

Science.gov (United States)

Hamkins, Jon

2010-01-01

Deep space communications over noisy channels lead to certain packets that are not decodable. These packets leave gaps, or bursts of erasures, in the data stream. Burst erasure correcting codes overcome this problem. These are forward erasure correcting codes that allow one to recover the missing gaps of data. Much of the recent work on this topic concentrated on Low-Density Parity-Check (LDPC) codes. These are more complicated to encode and decode than Single Parity Check (SPC) codes or Reed-Solomon (RS) codes, and so far have not been able to achieve the theoretical limit for burst erasure protection. A block interleaved maximum distance separable (MDS) code (e.g., an SPC or RS code) offers near-optimal burst erasure protection, in the sense that no other scheme of equal total transmission length and code rate could improve the guaranteed correctible burst erasure length by more than one symbol. The optimality does not depend on the length of the code, i.e., a short MDS code block interleaved to a given length would perform as well as a longer MDS code interleaved to the same overall length. As a result, this approach offers lower decoding complexity with better burst erasure protection compared to other recent designs for the burst erasure channel (e.g., LDPC codes). A limitation of the design is its lack of robustness to channels that have impairments other than burst erasures (e.g., additive white Gaussian noise), making its application best suited for correcting data erasures in layers above the physical layer. The efficiency of a burst erasure code is the length of its burst erasure correction capability divided by the theoretical upper limit on this length. The inefficiency is one minus the efficiency. The illustration compares the inefficiency of interleaved RS codes to Quasi-Cyclic (QC) LDPC codes, Euclidean Geometry (EG) LDPC codes, extended Irregular Repeat Accumulate (eIRA) codes, array codes, and random LDPC codes previously proposed for burst erasure

Gamma-Ray Bursts: 4th Huntsville Symposium. Proceedings

International Nuclear Information System (INIS)

Meegan, C.A.; Preece, R.D.; Koshut, T.M.

1998-01-01

These proceedings represent papers presented at the Fourth Huntsville Gamma-Ray Bursts Symposium held in September, 1997 in Huntsville, Alabama, USA. This conference occurred at a crucial time in the history of the gamma-ray burst research. In early 1997, 30 years after the detection of the first gamma-ray burst by the Vela satellites, counterparts to bursts were finally detected at optical and radio wavelengths. The symposium attracted about 200 scientists from 16 countries. Some of the topics discussed include gamma-ray burst spectra, x-ray observations, optical observations, radio observations, host galaxies, shocks and afterglows and models of gamma-ray bursts. There were 183 papers presented, out of these, 16 have been abstracted for the Energy Science and Technology database

X-ray echoes from gamma-ray bursts

International Nuclear Information System (INIS)

Dermer, C.D.; Hurley, K.C.; Hartmann, D.H.

1991-01-01

The identification of an echo of reflected radiation in time histories of gamma-ray burst spectra can provide important information about the existence of binary companions or accretion disks in gamma-ray burst systems. Because of the nature of Compton scattering, the spectrum of the echo will be attenuated at gamma-ray energies compared with the spectrum of the primary burst emission. The expected temporal and spectral signatures of the echo and a search for such echoes are described, and implications for gamma-ray burst models are discussed. 35 refs

Detecting pipe bursts by monitoring water demand

NARCIS (Netherlands)

Bakker, M.; Vreeburg, J.H.G.; Van der Roer, M.; Sperber, V.

2012-01-01

An algorithm which compares measured and predicted water demands to detect pipe bursts was developed and tested on three data sets of water demand and reported pipe bursts of three years. The algorithm proved to be able to detect bursts where the water loss exceeds 30% of the average water demand in

Fine structure in fast drift storm bursts

International Nuclear Information System (INIS)

McConnell, D.; Ellis, G.R.A.

1981-01-01

Recent observations with high time resolution of fast drift storm (FDS) solar bursts are described. A new variety of FDS bursts characterised by intensity maxima regularly placed in the frequency domain is reported. Possible interpretations of this are mentioned and the implications of the short duration of FDS bursts are discussed. (orig.)

Bursting neurons and ultrasound avoidance in crickets

Directory of Open Access Journals (Sweden)

Gary eMarsat

2012-07-01

Full Text Available Decision making in invertebrates often relies on simple neural circuits composed of only a few identified neurons. The relative simplicity of these circuits makes it possible to identify the key computation and neural properties underlying decisions. In this review, we summarize recent research on the neural basis of ultrasound avoidance in crickets, a response that allows escape from echolocating bats. The key neural property shaping behavioral output is high-frequency bursting of an identified interneuron, AN2, which carries information about ultrasound stimuli from receptor neurons to the brain. AN2's spike train consists of clusters of spikes –bursts– that may be interspersed with isolated, non-burst spikes. AN2 firing is necessary and sufficient to trigger avoidance steering but only high-rate firing, such as occurs in bursts, evokes this response. AN2 bursts are therefore at the core of the computation involved in deciding whether or not to steer away from ultrasound. Bursts in AN2 are triggered by synaptic input from nearly synchronous bursts in ultrasound receptors. Thus the population response at the very first stage of sensory processing –the auditory receptor- already differentiates the features of the stimulus that will trigger a behavioral response from those that will not. Adaptation, both intrinsic to AN2 and within ultrasound receptors, scales the burst-generating features according to the stimulus statistics, thus filtering out background noise and ensuring that bursts occur selectively in response to salient peaks in ultrasound intensity. Furthermore AN2’s sensitivity to ultrasound varies adaptively with predation pressure, through both developmental and evolutionary mechanisms. We discuss how this key relationship between bursting and the triggering of avoidance behavior is also observed in other invertebrate systems such as the avoidance of looming visual stimuli in locusts or heat avoidance in beetles.

NICER Eyes on Bursting Stars

Science.gov (United States)

Kohler, Susanna

2018-03-01

What happens to a neutron stars accretion disk when its surface briefly explodes? A new instrument recently deployed at the International Space Station (ISS) is now watching bursts from neutron stars and reporting back.Deploying a New X-Ray MissionLaunch of NICER aboard a Falcon 9 rocket in June 2017. [NASA/Tony Gray]In early June of 2017, a SpaceX Dragon capsule on a Falcon 9 rocket launched on a resupply mission to the ISS. The pressurized interior of the Dragon contained the usual manifest of crew supplies, spacewalk equipment, and vehicle hardware. But the unpressurized trunk of the capsule held something a little different: the Neutron star Interior Composition Explorer (NICER).In the two weeks following launch, NICER was extracted from the SpaceX Dragon capsule and installed on the ISS. And by the end of the month, the instrument was already collecting its first data set: observations of a bright X-ray burst from Aql X-1, a neutron star accreting matter from a low-mass binary companion.Impact of BurstsNICERs goal is to provide a new view of neutron-star physics at X-ray energies of 0.212 keV a window that allows us to explore bursts of energy that neutron stars sometimes emit from their surfaces.Artists impression of an X-ray binary, in which a compact object accretes material from a companion star. [ESA/NASA/Felix Mirabel]In X-ray burster systems, hydrogen- and helium-rich material from a low-mass companion star piles up in an accretion disk around the neutron star. This material slowly funnels onto the neutron stars surface, forming a layer that gravitationally compresses and eventually becomes so dense and hot that runaway nuclear fusion ignites.Within seconds, the layer of material is burned up, producing a burst of emission from the neutron star that outshines even the inner regions of the hot accretion disk. Then more material funnels onto the neutron star and the process begins again.Though we have a good picture of the physics that causes these bursts

INTEGRAL monitoring of unusually long X-ray bursts

DEFF Research Database (Denmark)

Chenevez, Jérôme; Falanga, M.; Kuulkers, E.

2008-01-01

of exceptional burst events lasting more than ~10 minutes. Half of the dozen so-called intermediate long bursts registered so far have been observed by INTEGRAL. The goal is to derive a comprehensive picture of the relationship between the nuclear ignition processes and the accretion states of the system leading...... up to such long bursts. Depending on the composition of the accreted material, these bursts may be explained by either the unstable burning of a large pile of mixed hydrogen and helium, or the ignition of a thick pure helium layer. Intermediate long bursts are particularly expected to occur at very...

Chronic intermittent hypoxia induces cardiac inflammation and dysfunction in a rat obstructive sleep apnea model.

Science.gov (United States)

Wei, Qin; Bian, Yeping; Yu, Fuchao; Zhang, Qiang; Zhang, Guanghao; Li, Yang; Song, Songsong; Ren, Xiaomei; Tong, Jiayi

2016-11-01

Chronic intermittent hypoxia is considered to play an important role in cardiovascular pathogenesis during the development of obstructive sleep apnea (OSA). We used a well-described OSA rat model induced with simultaneous intermittent hypoxia. Male Sprague Dawley rats were individually placed into plexiglass chambers with air pressure and components were electronically controlled. The rats were exposed to intermittent hypoxia 8 hours daily for 5 weeks. The changes of cardiac structure and function were examined by ultrasound. The cardiac pathology, apoptosis, and fibrosis were analyzed by H&E staining, TUNNEL assay, and picosirius staining, respectively. The expression of inflammation and fibrosis marker genes was analyzed by quantitative real-time PCR and Western blot. Chronic intermittent hypoxia/low pressure resulted in significant increase of left ventricular internal diameters (LVIDs), end-systolic volume (ESV), end-diastolic volume (EDV), and blood lactate level and marked reduction in ejection fraction and fractional shortening. Chronic intermittent hypoxia increased TUNNEL-positive myocytes, disrupted normal arrangement of cardiac fibers, and increased Sirius stained collagen fibers. The expression levels of hypoxia induced factor (HIF)-1α, NF-kB, IL-6, and matrix metallopeptidase 2 (MMP-2) were significantly increased in the heart of rats exposed to chronic intermittent hypoxia. In conclusion, the left ventricular function was adversely affected by chronic intermittent hypoxia, which is associated with increased expression of HIF-1α and NF-kB signaling molecules and development of cardiac inflammation, apoptosis and fibrosis. © 2016 by the Journal of Biomedical Research. All rights reserved.

Observation of cosmic gamma ray burst by Hinotori

International Nuclear Information System (INIS)

Okudaira, Kiyoaki; Yoshimori, Masato; Hirashima, Yo; Kondo, Ichiro.

1982-01-01

The solar gamma ray detecor (SGR) on Hinotori has no collimator, and the collimator of a hard X-ray monitor is not effective for gamma ray with energy more than 100 KeV. Accordingly, the detection system can detect cosmic gamma ray burst, and two bursts were observed. The first burst was detected on February 28, 1981, and the source of the burst was in the direction of 81 degree from Venus. The time profile and the spectrum were observed. In July 21, 1981, the second burst was detected. The time profile obtained with the SGR was compared with those of PVO (Pioneer Venus Orbiter) and LASL-ISEE. The time difference among the data of time profiles indicated that the source of the burst was not the sun. The spectrum was also measured. (Kato, T.)

Advances in gamma-ray burst astronomy

International Nuclear Information System (INIS)

Cline, T.L.; Desai, U.D.

1976-01-01

Work at Goddard is presently being carried out in three major areas of gamma-ray burst research: (1) A pair of simultaneously operating 0.8-m 2 burst detectors were successfully balloon-borne at locations 800 miles apart on 9 May, 1975, each to atmospheric depths of 3 to 4 g cm -2 , for a 20-h period of coincident data coverage. This experiment investigates the size spectrum of bursts in the 10 -7 to 10 -6 erg cm -2 size region where dozens of events per day are expected on a -1.5 index integral power-law extrapolation. Considerable separation in latitude was used to avoid possible atmospheric and auroral secondary effects. Its results are not yet available. (2) A deep-space burst detector, the first spacecraft instrument built specifically for gamma-ray burst studies, was recently successfully integrated into the Helios-B space probe. Its use at distances of up to 2 AU will make possible the first high-resolution directional study of gamma-ray burst source locations. Similar modifications to several other space vehicles are also being prepared. (3) The gamma-ray instrument on the IMP-7 satellite is presently the most sensitive burst detector still operating in orbit. Its results have shown that all measured event-average energy spectra are consistent with being alike. Using this characteristic spectrum to select IMP-7 candidate events of smaller size than those detected using other spacecraft in coincidence, a size spectrum is constructed which fits the -1.5 index power law down to 2.5 x 10 -5 erg cm -2 per event, at an occurrence rate of about once per month. (Auth.)

A Novel QKD-based Secure Edge Router Architecture Design for Burst Confidentiality in Optical Burst Switched Networks

Science.gov (United States)

Balamurugan, A. M.; Sivasubramanian, A.

2014-06-01

The Optical Burst Switching (OBS) is an emergent result to the technology issue that could achieve a viable network in future. They have the ability to meet the bandwidth requisite of those applications that call for intensive bandwidth. The field of optical transmission has undergone numerous advancements and is still being researched mainly due to the fact that optical data transmission can be done at enormous speeds. The concept of OBS is still far from perfection facing issues in case of security threat. The transfer of optical switching paradigm to optical burst switching faces serious downfall in the fields of burst aggregation, routing, authentication, dispute resolution and quality of service (QoS). This paper proposes a framework based on QKD based secure edge router architecture design to provide burst confidentiality. The QKD protocol offers high level of confidentiality as it is indestructible. The design architecture was implemented in FPGA using diverse models and the results were taken. The results show that the proposed model is suitable for real time secure routing applications of the Optical burst switched networks.

3rd Interplanetary Network Gamma-Ray Burst Website

Science.gov (United States)

Hurley, Kevin

1998-05-01

We announce the opening of the 3rd Interplanetary Network web site at http://ssl.berkeley.edu/ipn3/index.html This site presently has four parts: 1. A bibliography of over 3000 publications on gamma-ray bursts, 2. IPN data on all bursts triangulated up to February 1998, 3. A master list showing which spacecraft observed which bursts, 4. Preliminary IPN data on the latest bursts observed.

THE INTERPLANETARY NETWORK SUPPLEMENT TO THE BURST AND TRANSIENT SOURCE EXPERIMENT 5B CATALOG OF COSMIC GAMMA-RAY BURSTS

International Nuclear Information System (INIS)

Hurley, K.; Briggs, M. S.; Kippen, R. M.; Kouveliotou, C.; Fishman, G.; Meegan, C.; Cline, T.; Trombka, J.; McClanahan, T.; Boynton, W.; Starr, R.; McNutt, R.; Boer, M.

2011-01-01

We present Interplanetary Network localization information for 343 gamma-ray bursts observed by the Burst and Transient Source Experiment (BATSE) between the end of the 4th BATSE catalog and the end of the Compton Gamma-Ray Observatory (CGRO) mission, obtained by analyzing the arrival times of these bursts at the Ulysses, Near Earth Asteroid Rendezvous (NEAR), and CGRO spacecraft. For any given burst observed by CGRO and one other spacecraft, arrival time analysis (or t riangulation ) results in an annulus of possible arrival directions whose half-width varies between 11 arcsec and 21 0 , depending on the intensity, time history, and arrival direction of the burst, as well as the distance between the spacecraft. This annulus generally intersects the BATSE error circle, resulting in an average reduction of the area of a factor of 20. When all three spacecraft observe a burst, the result is an error box whose area varies between 1 and 48,000 arcmin 2 , resulting in an average reduction of the BATSE error circle area of a factor of 87.

Intermittent Rivers and Biodiversity. Large scale analyses between hydrology and ecology in intermittent rivers

OpenAIRE

Blanchard, Q.

2014-01-01

Intermittent rivers are characterized by a temporary interruption of their flow which can manifest in a variety of ways, as much on a spatial scale as on a temporal one. This particular aspect of intermittent river hydrology gives rise to unique ecosystems, combining both aquatic and terrestrial habitats. Neglected for a long time by scientists and once considered biologically depauperate and ecologically unimportant, these fragile habitats are nowadays acknowledged for their rendered service...

Partition of aerobic and anaerobic swimming costs and their correlation to tail-beat frequency and burst activity in Sparus aurata

DEFF Research Database (Denmark)

Steffensen, John Fleng

2012-01-01

until fatigue at 10°C. The anaerobic swimming cost was measured as the excess postexercise oxygen consumption (EPOC) following each swimming speed. To determine tail-beat frequency, amplitude and burst and coast behaviour, the peduncle position was determined at 25 s·' by video tracking. The data showed......, and resulted in a total anaerobic capacity of 170 mg O2 kg·'. Normalized tail-beat amplitude and frequency both predicted the swimming speed but only tail-beat frequency was able to predict the aerobic swimming cost. The change to burst and coast swimming was correlated to the first measurements of EPOC...... and both the burst frequency (bursts min·') and burst distance (percentage burst distance) were found to predict EPOC by linear regressions. The low temperature used in the present study resulted in a prolonged recovery time, which increased with the anaerobic contribution to 10 hours after fatigue. Due...

Dynamic encoding of natural luminance sequences by LGN bursts.

Directory of Open Access Journals (Sweden)

Nicholas A Lesica

2006-07-01

Full Text Available In the lateral geniculate nucleus (LGN of the thalamus, visual stimulation produces two distinct types of responses known as tonic and burst. Due to the dynamics of the T-type Ca(2+ channels involved in burst generation, the type of response evoked by a particular stimulus depends on the resting membrane potential, which is controlled by a network of modulatory connections from other brain areas. In this study, we use simulated responses to natural scene movies to describe how modulatory and stimulus-driven changes in LGN membrane potential interact to determine the luminance sequences that trigger burst responses. We find that at low resting potentials, when the T channels are de-inactivated and bursts are relatively frequent, an excitatory stimulus transient alone is sufficient to evoke a burst. However, to evoke a burst at high resting potentials, when the T channels are inactivated and bursts are relatively rare, prolonged inhibitory stimulation followed by an excitatory transient is required. We also observe evidence of these effects in vivo, where analysis of experimental recordings demonstrates that the luminance sequences that trigger bursts can vary dramatically with the overall burst percentage of the response. To characterize the functional consequences of the effects of resting potential on burst generation, we simulate LGN responses to different luminance sequences at a range of resting potentials with and without a mechanism for generating bursts. Using analysis based on signal detection theory, we show that bursts enhance detection of specific luminance sequences, ranging from the onset of excitatory sequences at low resting potentials to the offset of inhibitory sequences at high resting potentials. These results suggest a dynamic role for burst responses during visual processing that may change according to behavioral state.

Low-Frequency Type III Bursts and Solar Energetic Particle Events

Science.gov (United States)

Gopalswamy, Nat; Makela, Pertti

2010-01-01

We analyzed the coronal mass ejections (CMEs), flares, and type 11 radio bursts associated with a set of six low frequency (15 min) normally used to define these bursts. All but one of the type III bursts was not associated with a type 11 burst in the metric or longer wavelength domains. The burst without type 11 burst also lacked a solar energetic particle (SEP) event at energies >25 MeV. The 1-MHz duration of the type III burst (28 min) is near the median value of type III durations found for gradual SEP events and ground level enhancement (GLE) events. Yet, there was no sign of SEP events. On the other hand, two other type III bursts from the same active region had similar duration but accompanied by WAVES type 11 bursts; these bursts were also accompanied by SEP events detected by SOHO/ERNE. The CMEs were of similar speeds and the flares are also of similar size and duration. This study suggests that the type III burst duration may not be a good indicator of an SEP event.

Putting intelligent structured intermittent auscultation (ISIA) into practice.

Science.gov (United States)

Maude, Robyn M; Skinner, Joan P; Foureur, Maralyn J

2016-06-01

Fetal monitoring guidelines recommend intermittent auscultation for the monitoring of fetal wellbeing during labour for low-risk women. However, these guidelines are not being translated into practice and low-risk women birthing in institutional maternity units are increasingly exposed to continuous cardiotocographic monitoring, both on admission to hospital and during labour. When continuous fetal monitoring becomes routinised, midwives and obstetricians lose practical skills around intermittent auscultation. To support clinical practice and decision-making around auscultation modality, the intelligent structured intermittent auscultation (ISIA) framework was developed. The purpose of this discussion paper is to describe the application of intelligent structured intermittent auscultation in practice. The intelligent structured intermittent auscultation decision-making framework is a knowledge translation tool that supports the implementation of evidence into practice around the use of intermittent auscultation for fetal heart monitoring for low-risk women during labour. An understanding of the physiology of the materno-utero-placental unit and control of the fetal heart underpin the development of the framework. Intelligent structured intermittent auscultation provides midwives with a robust means of demonstrating their critical thinking and clinical reasoning and supports their understanding of normal physiological birth. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

Nuclear-burst strength detecting and measuring device

International Nuclear Information System (INIS)

Balut, J.A.L.G.; Lemaire, P.E.G.K.; Loisy, C.M.

1976-01-01

A continuous-operation automatic device is described for detection and accurate measurement of the strength of a burst generating an emission from luminous or infrared sources. This device characterizes and analyzes the maxima and minima of a ''thermal flux/time'' curve. The device comprises a master time element and an assembly of photoelectric detectors, an electronic processing system coupled to the detectors, and a mechanical system securing the rigidity and positioning of the photoelectric detector assembly with respect to an octahedral prism based on a horizontal plane

Acute Effects of Carbohydrate Supplementation on Intermittent Sports Performance.

Science.gov (United States)

Baker, Lindsay B; Rollo, Ian; Stein, Kimberly W; Jeukendrup, Asker E

2015-07-14

Intermittent sports (e.g., team sports) are diverse in their rules and regulations but similar in the pattern of play; that is, intermittent high-intensity movements and the execution of sport-specific skills over a prolonged period of time (~1-2 h). Performance during intermittent sports is dependent upon a combination of anaerobic and aerobic energy systems, both of which rely on muscle glycogen and/or blood glucose as an important substrate for energy production. The aims of this paper are to review: (1) potential biological mechanisms by which carbohydrate may impact intermittent sport performance; (2) the acute effects of carbohydrate ingestion on intermittent sport performance, including intermittent high-intensity exercise capacity, sprinting, jumping, skill, change of direction speed, and cognition; and (3) what recommendations can be derived for carbohydrate intake before/during exercise in intermittent sports based on the available evidence. The most researched intermittent sport is soccer but some sport-specific studies have also been conducted in other sports (e.g., rugby, field hockey, basketball, American football, and racquet sports). Carbohydrate ingestion before/during exercise has been shown in most studies to enhance intermittent high-intensity exercise capacity. However, studies have shown mixed results with regards to the acute effects of carbohydrate intake on sprinting, jumping, skill, change of direction speed, and cognition. In most of these studies the amount of carbohydrate consumed was ~30-60 g/h in the form of a 6%-7% carbohydrate solution comprised of sucrose, glucose, and/or maltodextrin. The magnitude of the impact that carbohydrate ingestion has on intermittent sport performance is likely dependent on the carbohydrate status of the individual; that is, carbohydrate ingestion has the greatest impact on performance under circumstances eliciting fatigue and/or hypoglycemia. Accordingly, carbohydrate ingestion before and during a game

Flash photoionization of gamma-ray burst environments

Science.gov (United States)

Band, David L.; Hartmann, Dieter H.

1992-01-01

The H-alpha line emission that a flash-photoionized region emits is calculated. Archival transients, as well as various theoretical predictions, suggest that there may be significant ionizing flux. The limits on the line flux which might be observable indicate that the density must be fairly high for the recombination radiation to be observable. The intense burst radiation is insufficient to melt the dust which will be present in such a dense medium. This dust may attenuate the observable line emission, but does not attenuate the ionizing radiation before it ionizes the neutral medium surrounding the burst source. The dust can also produce a light echo. If there are indeed gamma-ray bursts in dense clouds, then it is possible that the burst was triggered by Bondi-Hoyle accretion from the dense medium, although it is unlikely on statistical grounds that all bursts occur in clouds.

The supernova-gamma-ray burst-jet connection.

Science.gov (United States)

Hjorth, Jens

2013-06-13

The observed association between supernovae and gamma-ray bursts represents a cornerstone in our understanding of the nature of gamma-ray bursts. The collapsar model provides a theoretical framework for this connection. A key element is the launch of a bipolar jet (seen as a gamma-ray burst). The resulting hot cocoon disrupts the star, whereas the (56)Ni produced gives rise to radioactive heating of the ejecta, seen as a supernova. In this discussion paper, I summarize the observational status of the supernova-gamma-ray burst connection in the context of the 'engine' picture of jet-driven supernovae and highlight SN 2012bz/GRB 120422A--with its luminous supernova but intermediate high-energy luminosity--as a possible transition object between low-luminosity and jet gamma-ray bursts. The jet channel for supernova explosions may provide new insights into supernova explosions in general.

Long X-ray burst monitoring with INTEGRAL

DEFF Research Database (Denmark)

X-ray bursts are thermonuclear explosions on the surface of accreting neutron stars in low mass X-ray binary systems. In the frame of the INTEGRAL observational Key Programme over the Galactic Center a good number of the known X-ray bursters are frequently being monitored. An international...... collaboration lead by the JEM-X team at the Danish National Space Center has proposed to exploit the improved sensitivity of the INTEGRAL instruments to investigate the observational properties and physics up to high energies of exceptional burst events lasting between a few tens of minutes and several hours....... Of special interest are low luminosity bursting sources that exhibit X-ray bursts of very different durations allowing to study the transition from a hydrogen-rich bursting regime to a pure helium regime and from helium burning to carbon burning. I will present results obtained from INTEGRAL archive data...

Frequency chirping during a fishbone burst

International Nuclear Information System (INIS)

Marchenko, V.S.; Reznik, S.N.

2011-01-01

It is shown that frequency chirping during fishbone activity can be attributed to the reactive torque exerted on the plasma during the instability burst, which slows down plasma rotation inside the q = 1 surface and reduces the mode frequency in the lab frame. Estimates show that the peak value of this torque can exceed the neutral beam torque in modern tokamaks. The simple line-broadened quasilinear burst model (Berk et al 1995 Nucl. Fusion 35 1661), properly adapted for the fishbone case, is capable of reproducing the key features of the bursting mode. (letter)

Coherent Structures and Intermittency in Plasma Turbulence

International Nuclear Information System (INIS)

Das, Amita; Kaw, Predhiman; Sen, Abhijit

2008-01-01

The paper discusses some fundamental issues related to the phenomenon of intermittency in plasma turbulence with particular reference to experimental observations in fusion devices. Intermittency is typically associated with the presence of coherent structures in turbulence. Since coherent structures can play an important role in governing the transport properties of a system they have received a great deal of attention in fusion research. We review some of the experimental measurements and numerical simulation studies on the presence and formation of coherent structures in plasmas and discuss their relevance to intermittency. Intermittency, as widely discussed in the context of neutral fluid turbulence, implies multiscaling behaviour in contrast to self-similar scaling patterns observed in self organized criticality (SOC) phenomenon. The experimental evidence from plasma turbulence measurements reveal a mixed picture--while some observations support the SOC model description others indicate the presence of multiscaling behaviour. We discuss these results in the light of our present understanding of plasma turbulence and in terms of certain unique aspects of intermittency as revealed by fluid models of plasmas.

Simulating X-ray bursts during a transient accretion event

Science.gov (United States)

Johnston, Zac; Heger, Alexander; Galloway, Duncan K.

2018-06-01

Modelling of thermonuclear X-ray bursts on accreting neutron stars has to date focused on stable accretion rates. However, bursts are also observed during episodes of transient accretion. During such events, the accretion rate can evolve significantly between bursts, and this regime provides a unique test for burst models. The accretion-powered millisecond pulsar SAX J1808.4-3658 exhibits accretion outbursts every 2-3 yr. During the well-sampled month-long outburst of 2002 October, four helium-rich X-ray bursts were observed. Using this event as a test case, we present the first multizone simulations of X-ray bursts under a time-dependent accretion rate. We investigate the effect of using a time-dependent accretion rate in comparison to constant, averaged rates. Initial results suggest that using a constant, average accretion rate between bursts may underestimate the recurrence time when the accretion rate is decreasing, and overestimate it when the accretion rate is increasing. Our model, with an accreted hydrogen fraction of X = 0.44 and a CNO metallicity of ZCNO = 0.02, reproduces the observed burst arrival times and fluences with root mean square (rms) errors of 2.8 h, and 0.11× 10^{-6} erg cm^{-2}, respectively. Our results support previous modelling that predicted two unobserved bursts and indicate that additional bursts were also missed by observations.

Review of GRANAT observations of gamma-ray bursts

DEFF Research Database (Denmark)

Terekhov, O.; Denissenko, D.; Sunyaev, R.

1995-01-01

The GRANAT observatory was launched into a high apogee orbit on 1 December, 1989. Three instruments onboard GRANAT - PHEBUS, WATCH and SIGMA are able to detect gamma-ray bursts in a very broad energy range from 6 keV up to 100 MeV. Over 250 gamma-ray bursts were detected. We discuss the results...... of the observations of the time histories and spectral evolution of the detected events provided by the different instruments in different energy ranges. Short Gamma-Ray Bursts ( 2 s) events. Evidence of the existence...... of four differently behaving componenents in gamma-ray burst spectra is discussed. Statistical properties of the gamma-ray burst sources based on the 5 years of observations with (∼ 10−6 erg/cm2) sensitivity as well as the results of high sensitivity (∼ 10−8 erg/cm2) search for Gamma-Ray Bursts within...

The impact of intermittent or sustained carbon dioxide on intermittent hypoxia initiated respiratory plasticity. What is the effect of these combined stimuli on apnea severity?

Science.gov (United States)

Mateika, Jason H; Panza, Gino; Alex, Raichel; El-Chami, Mohamad

2017-10-31

The following review explores the effect that intermittent or sustained hypercapnia coupled to intermittent hypoxia has on respiratory plasticity. The review explores published work which suggests that intermittent hypercapnia leads to long-term depression of respiration when administered in isolation and prevents the initiation of long-term facilitation when administered in combination with intermittent hypoxia. The review also explores the impact that sustained hypercapnia alone and in combination with intermittent hypoxia has on the magnitude of long-term facilitation. After exploring the outcomes linked to intermittent hypoxia/hypercapnia and intermittent hypoxia/sustained hypercapnia the translational relevance of the outcomes as it relates to breathing stability during sleep is addressed. The likelihood that naturally induced cycles of intermittent hypoxia, coupled to oscillations in carbon dioxide that range between hypocapnia and hypercapnia, do not initiate long-term facilitation is addressed. Moreover, the conditions under which intermittent hypoxia/sustained hypercapnia could serve to improve breathing stability and mitigate co-morbidities associated with sleep apnea are considered. Published by Elsevier B.V.

Near stellar sources of gamma-ray bursts

OpenAIRE

Luchkov, B. I.; Markin, P. D.

2012-01-01

Correlation analysis of gamma-ray burst coordinates and nearby stars, registered on 2008-2011, revealed 5 coincidences with angular accuracy better than 0.1 degree. The random probability is $7\\times 10^{-7}$, so evidencing that coincident stars are indeed gamma-ray burst sources. The proposed method should be continued in order to provide their share in common balance of cosmic gamma-ray bursts.

Knockdown of angiopoietin-like 2 mimics the benefits of intermittent fasting on insulin responsiveness and weight loss.

Science.gov (United States)

Martel, Cécile; Pinçon, Anthony; Bélanger, Alexandre Maxime; Luo, Xiaoyan; Gillis, Marc-Antoine; de Montgolfier, Olivia; Thorin-Trescases, Nathalie; Thorin, Éric

2018-01-01

Angiopoietin-like 2 (ANGPTL2) is an inflammatory adipokine linking obesity to insulin resistance. Intermittent fasting, on the other hand, is a lifestyle intervention able to prevent obesity and diabetes but difficult to implement and maintain. Our objectives were to characterize a link between ANGPTL2 and intermittent fasting and to investigate whether the knockdown of ANGPTL2 reproduces the benefits of intermittent fasting on weight gain and insulin responsiveness in knockdown and wild-type littermates mice. Intermittent fasting, access to food ad libitum once every other day, was initiated at the age of three months and maintained for four months. Intermittent fasting decreased by 63% (p < 0.05) gene expression of angptl2 in adipose tissue of wild-type mice. As expected, intermittent fasting improved insulin sensitivity (p < 0.05) and limited weight gain (p < 0.05) in wild-type mice. Knockdown mice fed ad libitum, however, were comparable to wild-type mice following the intermittent fasting regimen: insulin sensitivity and weight gain were identical, while intermittent fasting had no additional impact on these parameters in knockdown mice. Energy intake was similar between both wild-type fed intermittent fasting and ANGPTL2 knockdown mice fed ad libitum, suggesting that intermittent fasting and knockdown of ANGPTL2 equally lower feeding efficiency. These results suggest that the reduction of ANGPTL2 could be a useful and promising strategy to prevent obesity and insulin resistance, although further investigation of the mechanisms linking ANGPTL2 and intermittent fasting is warranted. Impact statement Intermittent fasting is an efficient diet pattern to prevent weight gain and improve insulin sensitivity. It is, however, a difficult regimen to follow and compliance is expected to be very low. In this work, we demonstrate that knockdown of ANGPTL2 in mice fed ad libitum mimics the beneficial effects of intermittent fasting on weight gain and insulin

Gamma-Ray Burst Host Galaxies Have "Normal" Luminosities.

Science.gov (United States)

Schaefer

2000-04-10

The galactic environment of gamma-ray bursts can provide good evidence about the nature of the progenitor system, with two old arguments implying that the burst host galaxies are significantly subluminous. New data and new analysis have now reversed this picture: (1) Even though the first two known host galaxies are indeed greatly subluminous, the next eight hosts have absolute magnitudes typical for a population of field galaxies. A detailed analysis of the 16 known hosts (10 with redshifts) shows them to be consistent with a Schechter luminosity function with R*=-21.8+/-1.0, as expected for normal galaxies. (2) Bright bursts from the Interplanetary Network are typically 18 times brighter than the faint bursts with redshifts; however, the bright bursts do not have galaxies inside their error boxes to limits deeper than expected based on the luminosities for the two samples being identical. A new solution to this dilemma is that a broad burst luminosity function along with a burst number density varying as the star formation rate will require the average luminosity of the bright sample (>6x1058 photons s-1 or>1.7x1052 ergs s-1) to be much greater than the average luminosity of the faint sample ( approximately 1058 photons s-1 or approximately 3x1051 ergs s-1). This places the bright bursts at distances for which host galaxies with a normal luminosity will not violate the observed limits. In conclusion, all current evidence points to gamma-ray burst host galaxies being normal in luminosity.

Cosmology and the Subgroups of Gamma-ray Bursts

Directory of Open Access Journals (Sweden)

A. Mészáros

2011-01-01

Full Text Available Both short and intermediate gamma-ray bursts are distributed anisotropically in the sky (Mészáros, A. et al. ApJ, 539, 98 (2000, Vavrek, R. et al. MNRAS, 391, 1 741 (2008. Hence, in the redshift range, where these bursts take place, the cosmological principle is in doubt. It has already been noted that short bursts should be mainly at redshifts smaller than one (Mészáros, A. et al. Gamma-ray burst: Sixth Huntsville Symp., AIP, Vol. 1 133, 483 (2009; Mészáros, A. et al. Baltic Astron., 18, 293 (2009. Here we show that intermediate bursts should be at redshifts up to three.

Type III Radio Burst Duration and SEP Events

Science.gov (United States)

Gopalswamy, N.; Makela, P.; Xie, H.

2010-01-01

Long-duration (>15 min), low-frequency (25 MeV. The 1-MHz duration of the type III burst (28 rein) is near the median value of type III durations found for gradual SEP events and ground level enhancement (GLE) events. Yet, there was no sign of SEP events. On the other hand, two other type III bursts from the same active region had similar duration but accompanied by WAVES type 11 bursts; these bursts were also accompanied by SEP events detected by SOHO/ERNE. This study suggests that the type III burst duration may not be a good indicator of an SEP event, consistent with the statistical study of Cliver and Ling (2009, ApJ ).

Eddington-limited X-Ray Bursts as Distance Indicators. I. Systematic Trends and Spherical Symmetry in Bursts from 4U 1728-34

Science.gov (United States)

Galloway, Duncan K.; Psaltis, Dimitrios; Chakrabarty, Deepto; Muno, Michael P.

2003-06-01

We investigate the limitations of thermonuclear X-ray bursts as a distance indicator for the weakly magnetized accreting neutron star 4U 1728-34. We measured the unabsorbed peak flux of 81 bursts in public data from the Rossi X-Ray Timing Explorer (RXTE). The distribution of peak fluxes was bimodal: 66 bursts exhibited photospheric radius expansion (presumably reaching the local Eddington limit) and were distributed about a mean bolometric flux of 9.2×10-8ergscm-2s-1, while the remaining (non-radius expansion) bursts reached 4.5×10-8ergscm-2s-1, on average. The peak fluxes of the radius expansion bursts were not constant, exhibiting a standard deviation of 9.4% and a total variation of 46%. These bursts showed significant correlations between their peak flux and the X-ray colors of the persistent emission immediately prior to the burst. We also found evidence for quasi-periodic variation of the peak fluxes of radius expansion bursts, with a timescale of ~=40 days. The persistent flux observed with RXTE/ASM over 5.8 yr exhibited quasi-periodic variability on a similar timescale. We suggest that these variations may have a common origin in reflection from a warped accretion disk. Once the systematic variation of the peak burst fluxes is subtracted, the residual scatter is only ~=3%, roughly consistent with the measurement uncertainties. The narrowness of this distribution strongly suggests that (1) the radiation from the neutron star atmosphere during radius expansion episodes is nearly spherically symmetric and (2) the radius expansion bursts reach a common peak flux that may be interpreted as a standard candle intensity. Adopting the minimum peak flux for the radius expansion bursts as the Eddington flux limit, we derive a distance for the source of 4.4-4.8 kpc (assuming RNS=10 km), with the uncertainty arising from the probable range of the neutron star mass MNS=1.4-2 Msolar.

Intermittent hypoxia increases insulin resistance in genetically obese mice.

Science.gov (United States)

Polotsky, Vsevolod Y; Li, Jianguo; Punjabi, Naresh M; Rubin, Arnon E; Smith, Philip L; Schwartz, Alan R; O'Donnell, Christopher P

2003-10-01

Obstructive sleep apnoea, a syndrome that leads to recurrent intermittent hypoxia, is associated with insulin resistance in obese individuals, but the mechanisms underlying this association remain unknown. We utilized a mouse model to examine the effects of intermittent hypoxia on insulin resistance in lean C57BL/6J mice and leptin-deficient obese (C57BL/6J-Lepob) mice. In lean mice, exposure to intermittent hypoxia for 5 days (short term) resulted in a decrease in fasting blood glucose levels (from 173 +/- 11 mg dl-1 on day 0 to 138 +/- 10 mg dl-1 on day 5, P obese mice, short-term intermittent hypoxia led to a decrease in blood glucose levels accompanied by a 607 +/- 136 % (P intermittent hypoxia was completely abolished by prior leptin infusion. Obese mice exposed to intermittent hypoxia for 12 weeks (long term) developed a time-dependent increase in fasting serum insulin levels (from 3.6 +/- 1.1 ng ml-1 at baseline to 9.8 +/- 1.8 ng ml-1 at week 12, P intermittent hypoxia is dependent on the disruption of leptin pathways.

The Yo-Yo intermittent recovery test

DEFF Research Database (Denmark)

Bangsbo, Jens; Iaia, F. Marcello; Krustrup, Peter

2008-01-01

The two Yo-Yo intermittent recovery (IR) tests evaluate an individual's ability to repeatedly perform intense exercise. The Yo-Yo IR level 1 (Yo-Yo IR1) test focuses on the capacity to carry out intermittent exercise leading to a maximal activation of the aerobic system, whereas Yo-Yo IR level 2...

Association of solar flares with coronal mass ejections accompanied by Deca-Hectometric type II radio burst for two solar cycles 23 and 24

Science.gov (United States)

Kharayat, Hema; Prasad, Lalan; Pant, Sumit

2018-05-01

The aim of present study is to find the association of solar flares with coronal mass ejections (CMEs) accompanied by Deca-Hectometric (DH) type II radio burst for the period 1997-2014 (solar cycle 23 and ascending phase of solar cycle 24). We have used a statistical analysis and found that 10-20∘ latitudinal belt of northern region and 80-90∘ longitudinal belts of western region of the sun are more effective for flare-CME accompanied by DH type II radio burst events. M-class flares (52%) are in good association with the CMEs accompanied by DH type II radio burst. Further, we have calculated the flare position and found that most frequent flare site is at the center of the CME span. However, the occurrence probability of all flares is maximum outside the CME span. X-class flare associated CMEs have maximum speed than that of M, C, and B-class flare associated CMEs. We have also found a good correlation between flare position and central position angle of CMEs accompanied by DH type II radio burst.

Dynamic characterizers of spatiotemporal intermittency

OpenAIRE

Gupte, Neelima; Jabeen, Zahera

2006-01-01

Systems of coupled sine circle maps show regimes of spatiotemporally intermittent behaviour with associated scaling exponents which belong to the DP class, as well as regimes of spatially intermittent behaviour (with associated regular dynamical behaviour) which do not belong to the DP class. Both types of behaviour are seen along the bifurcation boundaries of the synchronized solutions, and contribute distinct signatures to the dynamical characterizers of the system, viz. the distribution of...

Bursts from the very early universe

International Nuclear Information System (INIS)

Silk, J.; Stodolsky, L.

2006-01-01

Bursts of weakly interacting particles such as neutrinos or even more weakly interacting particles such as wimps and gravitons from the very early universe would offer a much deeper 'look back time' to early epochs than is possible with photons. We consider some of the issues related to the existence of such bursts and their detectability. Characterizing the burst rate by a probability P per Hubble four-volume we find, for events in the radiation-dominated era, that the natural unit of description is the present intensity of the CMB times P. The existence of such bursts would make the observation of phenomena associated with very early times in cosmology at least conceptually possible. One might even hope to probe the transplanckian epoch if complexes more weakly interacting than the graviton can exist. Other conceivable applications include the potential detectability of the formation of 'pocket universes' in a multiverse

Dynamic Spectral Imaging of Decimetric Fiber Bursts in an Eruptive Solar Flare

Energy Technology Data Exchange (ETDEWEB)

Wang, Zhitao; Chen, Bin; Gary, Dale E., E-mail: zw56@njit.edu [Center for Solar-Terrestrial Research, New Jersey Institute of Technology, University Heights, Newark, NJ 07102 (United States)

2017-10-20

Fiber bursts are a type of fine structure that is often superposed on type IV radio continuum emission during solar flares. Although studied for many decades, its physical exciter, emission mechanism, and association with the flare energy release remain unclear, partly due to the lack of simultaneous imaging observations. We report the first dynamic spectroscopic imaging observations of decimetric fiber bursts, which occurred during the rise phase of a long-duration eruptive flare on 2012 March 3, as obtained by the Karl G. Jansky Very Large Array in 1–2 GHz. Our results show that the fiber sources are located near and above one footpoint of the flare loops. The fiber source and the background continuum source are found to be co-spatial and share the same morphology. It is likely that they are associated with nonthermal electrons trapped in the converging magnetic fields near the footpoint, as supported by a persistent coronal hard X-ray source present during the flare rise phase. We analyze three groups of fiber bursts in detail with dynamic imaging spectroscopy and obtain their mean frequency-dependent centroid trajectories in projection. By using a barometric density model and magnetic field based on a potential field extrapolation, we further reconstruct the 3D source trajectories of fiber bursts, for comparison with expectations from the whistler wave model and two MHD-based models. We conclude that the observed fiber burst properties are consistent with an exciter moving at the propagation velocity expected for whistler waves, or models that posit similar exciter velocities.

Acute Effects of Carbohydrate Supplementation on Intermittent Sports Performance

Directory of Open Access Journals (Sweden)

Lindsay B. Baker

2015-07-01

Full Text Available Intermittent sports (e.g., team sports are diverse in their rules and regulations but similar in the pattern of play; that is, intermittent high-intensity movements and the execution of sport-specific skills over a prolonged period of time (~1–2 h. Performance during intermittent sports is dependent upon a combination of anaerobic and aerobic energy systems, both of which rely on muscle glycogen and/or blood glucose as an important substrate for energy production. The aims of this paper are to review: (1 potential biological mechanisms by which carbohydrate may impact intermittent sport performance; (2 the acute effects of carbohydrate ingestion on intermittent sport performance, including intermittent high-intensity exercise capacity, sprinting, jumping, skill, change of direction speed, and cognition; and (3 what recommendations can be derived for carbohydrate intake before/during exercise in intermittent sports based on the available evidence. The most researched intermittent sport is soccer but some sport-specific studies have also been conducted in other sports (e.g., rugby, field hockey, basketball, American football, and racquet sports. Carbohydrate ingestion before/during exercise has been shown in most studies to enhance intermittent high-intensity exercise capacity. However, studies have shown mixed results with regards to the acute effects of carbohydrate intake on sprinting, jumping, skill, change of direction speed, and cognition. In most of these studies the amount of carbohydrate consumed was ~30–60 g/h in the form of a 6%–7% carbohydrate solution comprised of sucrose, glucose, and/or maltodextrin. The magnitude of the impact that carbohydrate ingestion has on intermittent sport performance is likely dependent on the carbohydrate status of the individual; that is, carbohydrate ingestion has the greatest impact on performance under circumstances eliciting fatigue and/or hypoglycemia. Accordingly, carbohydrate ingestion before

Relativistic motion in gamma-ray bursts

International Nuclear Information System (INIS)

Krolik, J.H.; Pier, E.A.

1991-01-01

Three fundamental problems affect models of gamma-ray bursts, i.e., the energy source, the ability of high-energy photons to escape the radiation region, and the comparative weakness of X-ray emission. It is indicated that relativistic bulk motion of the gamma-ray-emitting plasma generically provides a solution to all three of these problems. Results show that, if the plasma that produces gamma-ray bursts has a bulk relativistic velocity with Lorentz factor gamma of about 10, several of the most troubling problems having to do with gamma-ray bursts are solved. 42 refs

Green leaf volatiles and oxygenated metabolite emission bursts from mesquite branches following light-dark transitions.

Science.gov (United States)

Jardine, K; Barron-Gafford, G A; Norman, J P; Abrell, L; Monson, R K; Meyers, K T; Pavao-Zuckerman, M; Dontsova, K; Kleist, E; Werner, C; Huxman, T E

2012-09-01

Green leaf volatiles (GLVs) are a diverse group of fatty acid-derived compounds emitted by all plants and are involved in a wide variety of developmental and stress-related biological functions. Recently, GLV emission bursts from leaves were reported following light-dark transitions and hypothesized to be related to the stress response while acetaldehyde bursts were hypothesized to be due to the 'pyruvate overflow' mechanism. In this study, branch emissions of GLVs and a group of oxygenated metabolites (acetaldehyde, ethanol, acetic acid, and acetone) derived from the pyruvate dehydrogenase (PDH) bypass pathway were quantified from mesquite plants following light-dark transitions using a coupled GC-MS, PTR-MS, and photosynthesis system. Within the first minute after darkening following a light period, large emission bursts of both C(5) and C(6) GLVs dominated by (Z)-3-hexen-1-yl acetate together with the PDH bypass metabolites are reported for the first time. We found that branches exposed to CO(2)-free air lacked significant GLV and PDH bypass bursts while O(2)-free atmospheres eliminated the GLV burst but stimulated the PDH bypass burst. A positive relationship was observed between photosynthetic activity prior to darkening and the magnitude of the GLV and PDH bursts. Photosynthesis under (13)CO(2) resulted in bursts with extensive labeling of acetaldehyde, ethanol, and the acetate but not the C(6)-alcohol moiety of (Z)-3-hexen-1-yl acetate. Our observations are consistent with (1) the "pyruvate overflow" mechanism with a fast turnover time (3 h) responsible for the C(6) alcohol moiety of (Z)-3-hexen-1-yl acetate via the 13-lipoxygenase pathway. We conclude that our non-invasive method may provide a new valuable in vivo tool for studies of acetyl-CoA and fatty acid metabolism in plants at a variety of spatial scales.

THE FERMI –GBM THREE-YEAR X-RAY BURST CATALOG

Energy Technology Data Exchange (ETDEWEB)

Jenke, P. A. [CSPAR, SPA University of Alabama in Huntsville, Huntsville, AL 35805 (United States); Linares, M. [Instituto de Astrofísica de Canarias, c/Vía Láctea s/n, E-38205 La Laguna, Tenerife (Spain); Connaughton, V.; Camero-Arranz, A.; Finger, M. H. [Universities Space Research Association, Huntsville, AL 35805 (United States); Beklen, E. [Department of Physics, Suleyman Demirel University, 32260, Isparta (Turkey); Wilson-Hodge, C. A. [Marshall Space Flight Center, Huntsville, AL 35812 (United States)

2016-08-01

The Fermi Gamma-ray Burst Monitor (GBM) is an all-sky gamma-ray monitor well known in the gamma-ray burst (GRB) community. Although GBM excels in detecting the hard, bright extragalactic GRBs, its sensitivity above 8 keV and its all-sky view make it an excellent instrument for the detection of rare, short-lived Galactic transients. In 2010 March, we initiated a systematic search for transients using GBM data. We conclude this phase of the search by presenting a three-year catalog of 1084 X-ray bursts. Using spectral analysis, location, and spatial distributions we classified the 1084 events into 752 thermonuclear X-ray bursts, 267 transient events from accretion flares and X-ray pulses, and 65 untriggered gamma-ray bursts. All thermonuclear bursts have peak blackbody temperatures broadly consistent with photospheric radius expansion (PRE) bursts. We find an average rate of 1.4 PRE bursts per day, integrated over all Galactic bursters within about 10 kpc. These include 33 and 10 bursts from the ultra-compact X-ray binaries 4U 0614+09 and 2S 0918-549, respectively. We discuss these recurrence times and estimate the total mass ejected by PRE bursts in our Galaxy.

Discovery of the short gamma-ray burst GRB 050709.

Science.gov (United States)

Villasenor, J S; Lamb, D Q; Ricker, G R; Atteia, J-L; Kawai, N; Butler, N; Nakagawa, Y; Jernigan, J G; Boer, M; Crew, G B; Donaghy, T Q; Doty, J; Fenimore, E E; Galassi, M; Graziani, C; Hurley, K; Levine, A; Martel, F; Matsuoka, M; Olive, J-F; Prigozhin, G; Sakamoto, T; Shirasaki, Y; Suzuki, M; Tamagawa, T; Vanderspek, R; Woosley, S E; Yoshida, A; Braga, J; Manchanda, R; Pizzichini, G; Takagishi, K; Yamauchi, M

2005-10-06

Gamma-ray bursts (GRBs) fall into two classes: short-hard and long-soft bursts. The latter are now known to have X-ray and optical afterglows, to occur at cosmological distances in star-forming galaxies, and to be associated with the explosion of massive stars. In contrast, the distance scale, the energy scale and the progenitors of the short bursts have remained a mystery. Here we report the discovery of a short-hard burst whose accurate localization has led to follow-up observations that have identified the X-ray afterglow and (for the first time) the optical afterglow of a short-hard burst; this in turn led to the identification of the host galaxy of the burst as a late-type galaxy at z = 0.16 (ref. 10). These results show that at least some short-hard bursts occur at cosmological distances in the outskirts of galaxies, and are likely to be caused by the merging of compact binaries.

The Drift Burst Hypothesis

DEFF Research Database (Denmark)

Christensen, Kim; Oomen, Roel; Renò, Roberto

are an expected and regular occurrence in financial markets that can arise through established mechanisms such as feedback trading. At a theoretical level, we show how to build drift bursts into the continuous-time Itô semi-martingale model in such a way that the fundamental arbitrage-free property is preserved......, currencies and commodities. We find that the majority of identified drift bursts are accompanied by strong price reversals and these can therefore be regarded as “flash crashes” that span brief periods of severe market disruption without any material longer term price impacts....

Multiparameter Monitoring and Prevention of Fault-Slip Rock Burst

Directory of Open Access Journals (Sweden)

Shan-chao Hu

2017-01-01

Full Text Available Fault-slip rock burst is one type of the tectonic rock burst during mining. A detailed understanding of the precursory information of fault-slip rock burst and implementation of monitoring and early warning systems, as well as pressure relief measures, are essential to safety production in deep mines. This paper first establishes a mechanical model of stick-slip instability in fault-slip rock bursts and then reveals the failure characteristics of the instability. Then, change rule of mining-induced stress and microseismic signals before the occurrence of fault-slip rock burst are proposed, and multiparameter integrated early warning methods including mining-induced stress and energy are established. Finally, pressure relief methods targeting large-diameter boreholes and coal seam infusion are presented in accordance with the occurrence mechanism of fault-slip rock burst. The research results have been successfully applied in working faces 2310 of the Suncun Coal Mine, and the safety of the mine has been enhanced. These research results improve the theory of fault-slip rock burst mechanisms and provide the basis for prediction and forecasting, as well as pressure relief, of fault-slip rock bursts.

Limits of the memory coefficient in measuring correlated bursts

Science.gov (United States)

Jo, Hang-Hyun; Hiraoka, Takayuki

2018-03-01

Temporal inhomogeneities in event sequences of natural and social phenomena have been characterized in terms of interevent times and correlations between interevent times. The inhomogeneities of interevent times have been extensively studied, while the correlations between interevent times, often called correlated bursts, are far from being fully understood. For measuring the correlated bursts, two relevant approaches were suggested, i.e., memory coefficient and burst size distribution. Here a burst size denotes the number of events in a bursty train detected for a given time window. Empirical analyses have revealed that the larger memory coefficient tends to be associated with the heavier tail of the burst size distribution. In particular, empirical findings in human activities appear inconsistent, such that the memory coefficient is close to 0, while burst size distributions follow a power law. In order to comprehend these observations, by assuming the conditional independence between consecutive interevent times, we derive the analytical form of the memory coefficient as a function of parameters describing interevent time and burst size distributions. Our analytical result can explain the general tendency of the larger memory coefficient being associated with the heavier tail of burst size distribution. We also find that the apparently inconsistent observations in human activities are compatible with each other, indicating that the memory coefficient has limits to measure the correlated bursts.

Bursts from the very early universe

Energy Technology Data Exchange (ETDEWEB)

Silk, J. [Department of Physics, University of Oxford, Oxford OX1 3RH (United Kingdom); Stodolsky, L. [Max-Planck-Institut fuer Physik, Foehringer Ring 6, 80805 Munich (Germany)]. E-mail: les@mppmu.mpg.de

2006-07-27

Bursts of weakly interacting particles such as neutrinos or even more weakly interacting particles such as wimps and gravitons from the very early universe would offer a much deeper 'look back time' to early epochs than is possible with photons. We consider some of the issues related to the existence of such bursts and their detectability. Characterizing the burst rate by a probability P per Hubble four-volume we find, for events in the radiation-dominated era, that the natural unit of description is the present intensity of the CMB times P. The existence of such bursts would make the observation of pheno associated with very early times in cosmology at least conceptually possible. One might even hope to probe the transplanckian epoch if complexes more weakly interacting than the graviton can exist. Other conceivable applications include the potential detectability of the formation of 'pocket universes' in a multiverse.

Prolapsing Gastric Polyp Causing Intermittent Gastric Outlet Obstruction.

Science.gov (United States)

Kosai, Nik Ritza; Gendeh, Hardip Singh; Norfaezan, Abdul Rashid; Razman, Jamin; Sutton, Paul Anthony; Das, Srijit

2015-06-01

Gastric polyps are often an incidental finding on upper gastrointestinal endoscopy, with an incidence up to 5%. The majority of gastric polyps are asymptomatic, occurring secondary to inflammation. Prior reviews discussed Helicobacter pylori (H pylori)-associated singular gastric polyposis; however, we present a rare and unusual case of recurrent multiple benign gastric polyposis post H pylori eradication resulting in intermittent gastric outlet obstruction. A 70-year-old independent male, Chinese in ethnicity, with a background of diabetes mellitus, hypertension, and a simple renal cyst presented with a combination of melena, anemia, and intermittent vomiting of partially digested food after meals. Initial gastroscopy was positive for H pylori; thus he was treated with H pylori eradication and proton pump inhibitors. Serial gastroscopy demonstrated multiple sessile gastric antral polyps, the largest measuring 4 cm. Histopathologic examination confirmed a benign hyperplastic lesion. Computed tomography identified a pyloric mass with absent surrounding infiltration or metastasis. A distal gastrectomy was performed, whereby multiple small pyloric polyps were found, the largest prolapsing into the pyloric opening, thus explaining the intermittent nature of gastric outlet obstruction. Such polyps often develop from gastric ulcers and, if left untreated, may undergo neoplasia to form malignant cells. A distal gastrectomy was an effective choice of treatment, taking into account the polyp size, quantity, and potential for malignancy as opposed to an endoscopic approach, which may not guarantee a complete removal of safer margins and depth. Therefore, surgical excision is favorable for multiple large gastric polyps with risk of malignancy.

Intermittent fasting up-regulates Fsp27/Cidec gene expression in white adipose tissue.

Science.gov (United States)

Karbowska, Joanna; Kochan, Zdzislaw

2012-03-01

Fat-specific protein of 27 kDa (FSP27) is a novel lipid droplet protein that promotes triacylglycerol storage in white adipose tissue (WAT). The regulation of the Fsp27 gene expression in WAT is largely unknown. We investigated the nutritional regulation of FSP27 in WAT. The effects of intermittent fasting (48 d, eight cycles of 3-d fasting and 3-d refeeding), caloric restriction (48 d), fasting-refeeding (3-d fasting and 3-d refeeding), and fasting (3 d) on mRNA expression of FSP27, peroxisome proliferator-activated receptor γ (PPARγ2), CCAAT/enhancer binding protein α (C/EBPα), and M isoform of carnitine palmitoyltransferase 1 (a positive control for PPARγ activation) in epididymal WAT and on serum triacylglycerol, insulin, and leptin levels were determined in Wistar rats. We also determined the effects of PPARγ activation by rosiglitazone or pioglitazone on FSP27 mRNA levels in primary rat adipocytes. Long-term intermittent fasting, in contrast to other dietary manipulations, significantly up-regulated Fsp27 gene expression in WAT. Moreover, in rats subjected to intermittent fasting, serum insulin levels were elevated; PPARγ2 and C/EBPα mRNA expression in WAT was increased, and there was a positive correlation of Fsp27 gene expression with PPARγ2 and C/EBPα mRNA levels. FSP27 mRNA expression was also increased in adipocytes treated with PPARγ agonists. Our study demonstrates that the transcription of the Fsp27 gene in adipose tissue may be induced in response to nutritional stimuli. Furthermore, PPARγ2, C/EBPα, and insulin may be involved in the nutritional regulation of FSP27. Thus intermittent fasting, despite lower caloric intake, may promote triacylglycerol deposition in WAT by increasing the expression of genes involved in lipid storage, such as Fsp27. Copyright © 2012 Elsevier Inc. All rights reserved.

Solar energetic particles and radio burst emission

Directory of Open Access Journals (Sweden)

Miteva Rositsa

2017-01-01

Full Text Available We present a statistical study on the observed solar radio burst emission associated with the origin of in situ detected solar energetic particles. Several proton event catalogs in the period 1996–2016 are used. At the time of appearance of the particle origin (flare and coronal mass ejection we identified radio burst signatures of types II, III and IV by inspecting dynamic radio spectral plots. The information from observatory reports is also accounted for during the analysis. The occurrence of solar radio burst signatures is evaluated within selected wavelength ranges during the solar cycle 23 and the ongoing 24. Finally, we present the burst occurrence trends with respect to the intensity of the proton events and the location of their solar origin.

Bright x-ray flares in gamma-ray burst afterglows.

Science.gov (United States)

Burrows, D N; Romano, P; Falcone, A; Kobayashi, S; Zhang, B; Moretti, A; O'brien, P T; Goad, M R; Campana, S; Page, K L; Angelini, L; Barthelmy, S; Beardmore, A P; Capalbi, M; Chincarini, G; Cummings, J; Cusumano, G; Fox, D; Giommi, P; Hill, J E; Kennea, J A; Krimm, H; Mangano, V; Marshall, F; Mészáros, P; Morris, D C; Nousek, J A; Osborne, J P; Pagani, C; Perri, M; Tagliaferri, G; Wells, A A; Woosley, S; Gehrels, N

2005-09-16

Gamma-ray burst (GRB) afterglows have provided important clues to the nature of these massive explosive events, providing direct information on the nearby environment and indirect information on the central engine that powers the burst. We report the discovery of two bright x-ray flares in GRB afterglows, including a giant flare comparable in total energy to the burst itself, each peaking minutes after the burst. These strong, rapid x-ray flares imply that the central engines of the bursts have long periods of activity, with strong internal shocks continuing for hundreds of seconds after the gamma-ray emission has ended.

Implications of fast radio bursts for superconducting cosmic strings

Energy Technology Data Exchange (ETDEWEB)

Yu, Yun-Wei [Institute of Astrophysics, Central China Normal University, 152 Luoyu Road, Wuhan 430079 (China); Cheng, Kwong-Sang [Department of Physics, The University of Hong Kong, Pokfulam Road, Hong Kong (China); Shiu, Gary; Tye, Henry, E-mail: yuyw@phy.ccnu.edu.cn, E-mail: hrspksc@hku.hk, E-mail: shiu@ust.hk, E-mail: iastye@ust.hk [Department of Physics and Institute for Advanced Study, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong (China)

2014-11-01

Highly beamed, short-duration electromagnetic bursts could be produced by superconducting cosmic string (SCS) loops oscillating in cosmic magnetic fields. We demonstrated that the basic characteristics of SCS bursts such as the electromagnetic frequency and the energy release could be consistently exhibited in the recently discovered fast radio bursts (FRBs). Moreover, it is first showed that the redshift distribution of the FRBs can also be well accounted for by the SCS burst model. Such agreements between the FRBs and SCS bursts suggest that the FRBs could originate from SCS bursts and thus they could provide an effective probe to study SCSs. The obtained values of model parameters indicate that the loops generating the FRBs have a small length scale and they are mostly formed in the radiation-dominated cosmological epoch.

Implications of fast radio bursts for superconducting cosmic strings

International Nuclear Information System (INIS)

Yu, Yun-Wei; Cheng, Kwong-Sang; Shiu, Gary; Tye, Henry

2014-01-01

Highly beamed, short-duration electromagnetic bursts could be produced by superconducting cosmic string (SCS) loops oscillating in cosmic magnetic fields. We demonstrated that the basic characteristics of SCS bursts such as the electromagnetic frequency and the energy release could be consistently exhibited in the recently discovered fast radio bursts (FRBs). Moreover, it is first showed that the redshift distribution of the FRBs can also be well accounted for by the SCS burst model. Such agreements between the FRBs and SCS bursts suggest that the FRBs could originate from SCS bursts and thus they could provide an effective probe to study SCSs. The obtained values of model parameters indicate that the loops generating the FRBs have a small length scale and they are mostly formed in the radiation-dominated cosmological epoch

Neutrino bursts and gravitational waves experiments

Energy Technology Data Exchange (ETDEWEB)

Castagnoli, C; Galeotti, P; Saavedra, O [Consiglio Nazionale delle Ricerche, Turin (Italy). Lab. di Cosmo-Geofisica

1978-05-01

Several experiments have been performed in many countries to observe gravitational waves or neutrino bursts. Since their simultaneous emission may occur in stellar collapse, the authors evaluate the effect of neutrino bursts on gravitational wave antennas and suggest the usefulness of a time correlation among the different detectors.

Sources of type III solar microwave bursts

Directory of Open Access Journals (Sweden)

Zhdanov D.A.

2016-06-01

Full Text Available Microwave fine structures allow us to study plasma evolution in an energy release region. The Siberian Solar Radio Telescope (SSRT is a unique instrument designed to examine fine structures at 5.7 GHz. A complex analysis of data from RATAN-600, 4–8 GHz spectropolarimeter, and SSRT, simultaneously with EUV data, made it possible to localize sources of III type microwave bursts in August 10, 2011 event within the entire frequency band of burst occurrence, as well as to determine the most probable region of primary energy release. To localize sources of III type bursts from RATAN-600 data, an original method for data processing has been worked out. At 5.7 GHz, the source of bursts was determined along two coordinates, whereas at 4.5, 4.7, 4.9, 5.1, 5.3, 5.5, and 6.0 GHz, their locations were identified along one coordinate. The size of the burst source at 5.1 GHz was found to be maximum as compared to those at other frequencies.

Intermittency in the particle production and in the nuclear multifragmentation

International Nuclear Information System (INIS)

Bozek, P.; Ploszajczak, M.

1991-01-01

Intermittency is a manifestation of scale invariance and randomness in physical systems. Intermittency in relativistic heavy-ion collisions and, in particular, the projectile dependence, multiplicity dependence and source-size dependence are discussed in the frame of the model of spatio-temporal intermittency. Moreover, recent theoretical results in intermittency studies of the nuclear multifragmentation are presented. (author) 35 refs., 4 figs., 1 tab

Beneficial effects of intermittent suction and pressure treatment in intermittent claudication

DEFF Research Database (Denmark)

Mehlsen, J; Himmelstrup, H; Himmelstrup, Bodil

1993-01-01

administration. The treatment caused significant increments in the ADP thresholds for platelet aggregation, while the effects on fibrinolysis were uncertain. It is concluded that intermittent suction and pressure treatment offers a new approach for conservative treatment of intermittent claudication....... participated in an open trial investigating the possible effects of the treatment on platelet aggregation and fibrinolysis. Pain-free and maximal walking distances were measured on a treadmill, and systolic blood pressure was measured on the upper limb, the ankle, and the first toe bilaterally. The threshold...... for adenosine diphosphate (ADP)-induced platelet aggregation was tested, and the fibrinolytic activity was estimated from the euglobulin clot lysis time. Active treatment resulted in significant improvements in pain-free and maximal walking distances, whereas no changes could be found during placebo...

Intermittency and random matrices

Science.gov (United States)

Sokoloff, Dmitry; Illarionov, E. A.

2015-08-01

A spectacular phenomenon of intermittency, i.e. a progressive growth of higher statistical moments of a physical field excited by an instability in a random medium, attracted the attention of Zeldovich in the last years of his life. At that time, the mathematical aspects underlying the physical description of this phenomenon were still under development and relations between various findings in the field remained obscure. Contemporary results from the theory of the product of independent random matrices (the Furstenberg theory) allowed the elaboration of the phenomenon of intermittency in a systematic way. We consider applications of the Furstenberg theory to some problems in cosmology and dynamo theory.

Spectra of gamma-ray bursts at high energies

International Nuclear Information System (INIS)

Matz, S.M.

1986-01-01

Between 1980 February and 1983 August the Gamma-Ray Spectrometer (GRS) on the Solar Maximum Mission satellite (SMM) observed 71 gamma-ray bursts. These events form a representative subset of the class of classical gamma-ray bursts. Since their discovery more than 15 years ago, hundreds of gamma-ray bursts have been detected; however, most observations have been limited to an energy range of roughly 30 keV-1 MeV. The large sensitive area and spectral range of the GRS allow, for the first time, an investigation of the high energy (>1 MeV) behavior of a substantial number of gamma-ray bursts. It is found that high-energy emission is seen in a large fraction of all events and that the data are consistent with all bursts emitting to at least 5 MeV with no cut-offs. Further, no burst spectrum measured by GRS has a clear high-energy cut-off. The high-energy emission can be a significant part of the total burst energy on the average about 30% of the observed energy above 30 keV is contained in the >1 MeV photons. The fact that the observations are consistent with the presence of high-energy emission in all events implies a limit on the preferential beaming of high-energy photons, from any mechanism. Single-photon pair-production in a strong magnetic field produces such beaming; assuming that the low-energy emission is isotropic, the data imply an upper limit of 1 x 10 12 G on the typical magnetic field at burst radiation sites

Focused Study of Thermonuclear Bursts on Neutron Stars

Science.gov (United States)

Chenevez, Jérôme

2009-05-01

X-ray bursters form a class of Low Mass X-Ray Binaries where accreted material from a donor star undergoes rapid thermonuclear burning in the surface layers of a neutron star. The flux released can temporarily exceed the Eddington limit and drive the photosphere to large radii. Such photospheric radius expansion bursts likely eject nuclear burning ashes into the interstellar medium, and may make possible the detection of photoionization edges. Indeed, theoretical models predict that absorption edges from 58Fe at 9.2 keV, 60Zn and 62Zn at 12.2 keV should be detectable by the future missions Simbol-X and NuSTAR. A positive detection would thus probe the nuclear burning as well as the gravitational redshift from the neutron star. Moreover, likely observations of atomic X-ray spectral components reflected from the inner accretion disk have been reported. The high spectral resolution capabilities of the focusing X-ray telescopes may therefore make possible to differentiate between the potential interpretations of the X-ray bursts spectral features.

Intermittent behavior of the logistic system

Science.gov (United States)

Mayer-Kress, G.; Haken, H.

1981-03-01

In the discrete logistic model a transition to chaotic behavior via intermittency occurs in a neighborhood of periodic bands. Intermittent behavior is also induced if a stable periodic orbit is perturbed by low-level external noise, whereas alterations due to computer digitalisation produce remarkable periodicities. We compare our numerical results with the predictions of Pomeau and Manneville for the Lorenz system.

Powerful Radio Burst Indicates New Astronomical Phenomenon

Science.gov (United States)

2007-09-01

Astronomers studying archival data from an Australian radio telescope have discovered a powerful, short-lived burst of radio waves that they say indicates an entirely new type of astronomical phenomenon. Region of Strong Radio Burst Visible-light (negative greyscale) and radio (contours) image of Small Magellanic Cloud and area where burst originated. CREDIT: Lorimer et al., NRAO/AUI/NSF Click on image for high-resolution file ( 114 KB) "This burst appears to have originated from the distant Universe and may have been produced by an exotic event such as the collision of two neutron stars or the death throes of an evaporating black hole," said Duncan Lorimer, Assistant Professor of Physics at West Virginia University (WVU) and the National Radio Astronomy Observatory (NRAO). The research team led by Lorimer consists of Matthew Bailes of Swinburne University in Australia, Maura McLaughlin of WVU and NRAO, David Narkevic of WVU, and Fronefield Crawford of Franklin and Marshall College in Lancaster, Pennsylvania. The astronomers announced their findings in the September 27 issue of the online journal Science Express. The startling discovery came as WVU undergraduate student David Narkevic re-analyzed data from observations of the Small Magellanic Cloud made by the 210-foot Parkes radio telescope in Australia. The data came from a survey of the Magellanic Clouds that included 480 hours of observations. "This survey had sought to discover new pulsars, and the data already had been searched for the type of pulsating signals they produce," Lorimer said. "We re-examined the data, looking for bursts that, unlike the usual ones from pulsars, are not periodic," he added. The survey had covered the Magellanic Clouds, a pair of small galaxies in orbit around our own Milky Way Galaxy. Some 200,000 light-years from Earth, the Magellanic Clouds are prominent features in the Southern sky. Ironically, the new discovery is not part of these galaxies, but rather is much more distant

Aliasing of the Schumann resonance background signal by sprite-associated Q-bursts

Science.gov (United States)

Guha, Anirban; Williams, Earle; Boldi, Robert; Sátori, Gabriella; Nagy, Tamás; Bór, József; Montanyà, Joan; Ortega, Pascal

2017-12-01

The Earth's naturally occurring Schumann resonances (SR) are composed of a quasi-continuous background component and a larger-amplitude, short-duration transient component, otherwise called 'Q-burst' (Ogawa et al., 1967). Sprites in the mesosphere are also known to accompany the energetic positive ground flashes that launch the Q-bursts (Boccippio et al., 1995). Spectra of the background Schumann Resonances (SR) require a natural stabilization period of ∼10-12 min for the three conspicuous modal parameters to be derived from Lorentzian fitting. Before the spectra are computed and the fitting process is initiated, the raw time series data need to be properly filtered for local cultural noise, narrow band interference as well as for large transients in the form of global Q-bursts. Mushtak and Williams (2009) describe an effective technique called Isolated Lorentzian (I-LOR), in which, the contributions from local cultural and various other noises are minimized to a great extent. An automated technique based on median filtering of time series data has been developed. These special lightning flashes are known to have greater contribution in the ELF range (below 1 kHz) compared to general negative CG strikes (Huang et al., 1999; Cummer et al., 2006). The global distributions of these Q-bursts have been studied by Huang et al. (1999) Rhode Island, USA by wave impedance methods from single station ELF measurements at Rhode Island, USA and from Japan Hobara et al. (2006). The present work aims to demonstrate the effect of Q-bursts on SR background spectra using GPS time-stamped observation of TLEs. It is observed that the Q-bursts selected for the present work do alias the background spectra over a 5-s period, though the amplitudes of these Q-bursts are far below the background threshold of 16 Core Standard Deviation (CSD) so that they do not strongly alias the background spectra of 10-12 min duration. The examination of one exceptional Q-burst shows that appreciable

Intermittent hydronephrosis

International Nuclear Information System (INIS)

Knop, J.; Vogel, H.; Hupe, W.

1981-01-01

An intermittent hydronephrosis was observed in a 40-year old patient. This disease pattern is due to an incongruity between the formation of urine and the transport capacity in the ureteropelvic junction. The latent impediment of flow becomes manifest with increased urine secretion. Irreversible renal damage can be the result of the repeatedly occurring hydronephrotic crises. (orig.) [de

A novel inclusion of intermittent generation resources in long term energy auctions

International Nuclear Information System (INIS)

Marambio, Rodrigo; Rudnick, Hugh

2017-01-01

Long term energy auctions are positioning as a valuable tool in order to attract new investments into power systems, especially in Latin American countries where emergent economies characteristics and their correspondent risks are usually present. Even though the focus of these auctions is the long term, there are short term issues involved which actual auction designs fail to include, resulting in an energy allocation that is not necessarily optimal for the system, a condition which becomes more evident in the presence of intermittent renewable technologies. A novel mechanism is formulated to obtain the optimal allocation in long term energy auctions, considering short term generation profiles from both intermittent and conventional base load technologies, and also their risk aversions. The proposed mechanism is developed and simulations are made for some scenarios in the Chilean power market, with different levels of renewable penetration. Significant cost savings are achieved for the final consumers in relation to energy purchases, in comparison with a mechanism that follows the demand profile. As more renewable intermittent capacity enters the power system it is evident the need for changes in the energy auctions allocation mechanisms, including elements to exploit the synergies among participants in the short term. - Highlights: • Risk management consideration in technology neutral auctions allocation. • Allocation mechanism in technology neutral auctions with intermittent technologies. • Renewable and conventional technologies energy auction offer curves. • Increase bid prices in auctions as a consequence of solar technology support.

Chimera states in bursting neurons

OpenAIRE

Bera, Bidesh K.; Ghosh, Dibakar; Lakshmanan, M.

2015-01-01

We study the existence of chimera states in pulse-coupled networks of bursting Hindmarsh-Rose neurons with nonlocal, global and local (nearest neighbor) couplings. Through a linear stability analysis, we discuss the behavior of stability function in the incoherent (i.e. disorder), coherent, chimera and multi-chimera states. Surprisingly, we find that chimera and multi-chimera states occur even using local nearest neighbor interaction in a network of identical bursting neurons alone. This is i...

US Army Nuclear Burst Detection System (NBDS)

International Nuclear Information System (INIS)

Glaser, R.F.

1980-07-01

The Nuclear Burst Detection System (NBDS) was developed to meet the Army requirements of an unattended, automatic nuclear burst reporting system. It provides pertinent data for battlefield commanders on a timely basis with high reliability

X-ray bursts from GX 17+2: a new approach

International Nuclear Information System (INIS)

Sztajno, M.; Langmeier, A.; Truemper, J.; Pietsch, W.; Paradijs, J. van; Lewin, W.H.G.; Massachusetts Inst. of Tech., Cambridge

1986-01-01

The detection of two X-ray bursts from GX 17+2 is reported; a short one (lasting about 10s), and a long one (which lasted about 5 min). These bursts reached a maximum intensity of only about 40 per cent above the persistent flux level. Like previous long bursts observed from GX 17+2 the long burst showed little softening during its decay, and it is difficult at first glance to classify it as either a type 1 or a type 2 burst. Following the recent results of two of the authors a time-dependent spectral analysis of these bursts has been made. (author)

Cosmic gamma-ray bursts

International Nuclear Information System (INIS)

Hurley, K.

1989-01-01

This paper reviews the essential aspects of the gamma-ray burst (GRB) phenomenon, with emphasis on the more recent results. GRBs are introduced by their time histories, which provide some evidence for a compact object origin. The energy spectra of bursts are presented and they are seen to demonstrate practically unambiguously that the origin of some GRBs involves neutron stars. Counterpart searches are reviewed briefly and the statistical properties of bursters treated. This paper presents a review of the three known repeating bursters (the Soft Gamma Repeaters). Extragalactic and galactic models are discussed and future prospects are assessed

Leader neurons in population bursts of 2D living neural networks

International Nuclear Information System (INIS)

Eckmann, J-P; Zbinden, Cyrille; Jacobi, Shimshon; Moses, Elisha; Marom, Shimon

2008-01-01

Eytan and Marom (2006 J. Neurosci. 26 8465-76) recently showed that the spontaneous bursting activity of rat neuron cultures includes 'first-to-fire' cells that consistently fire earlier than others. Here, we analyze the behavior of these neurons in long-term recordings of spontaneous activity of rat hippocampal and rat cortical neuron cultures from three different laboratories. We identify precursor events that may either subside ('aborted bursts') or can lead to a full-blown burst ('pre-bursts'). We find that the activation in the pre-burst typically has a first neuron ('leader'), followed by a localized response in its neighborhood. Locality is diminished in the bursts themselves. The long-term dynamics of the leaders is relatively robust, evolving with a half-life of 23-34 h. Stimulation of the culture alters the leader distribution, but the distribution stabilizes within about 1 h. We show that the leaders carry information about the identity of the burst, as measured by the signature of the number of spikes per neuron in a burst. The number of spikes from leaders in the first few spikes of a precursor event is furthermore shown to be predictive with regard to the transition into a burst (pre-burst versus aborted burst). We conclude that the leaders play a role in the development of the bursts and conjecture that they are part of an underlying sub-network that is excited first and then acts as a nucleation center for the burst

Effect of superoxide anion scavenger on rat hearts with chronic intermittent hypoxia.

Science.gov (United States)

Pai, Peiying; Lai, Ching Jung; Lin, Ching-Yuang; Liou, Yi-Fan; Huang, Chih-Yang; Lee, Shin-Da

2016-04-15

Only very limited information regarding the protective effects of the superoxide anion scavenger on chronic intermittent hypoxia-induced cardiac apoptosis is available. The purpose of this study is to evaluate the effects of the superoxide anion scavenger on cardiac apoptotic and prosurvival pathways in rats with sleep apnea. Forty-two Sprague-Dawley rats were divided into three groups, rats with normoxic exposure (Control, 21% O2, 1 mo), rats with chronic intermittent hypoxia exposure (Hypoxia, 3-7% O2vs. 21% O2per 40 s cycle, 8 h per day, 1 mo), and rats with pretreatment of the superoxide anion scavenger and chronic intermittent hypoxia exposure (Hypoxia-O2 (-)-Scavenger, MnTMPyP pentachloride, 1 mg/kg ip per day; 3-7% O2vs. 21% O2per 40 s cycle, 8 h per day, 1 mo) at 5-6 mo of age. After 1 mo, the protein levels and apoptotic cells of excised hearts from three groups were measured by Western blotting and terminal deoxynucleotide transferase-mediated dUTP nick end labeling (TUNEL) assay. The superoxide anion scavenger decreased hypoxia-induced myocardial architecture abnormalities, left ventricular hypertrophy, and TUNEL-positive apoptosis. The superoxide anion scavenger decreased hypoxia-induced Fas ligand, Fas death receptors, Fas-associated death domain (FADD), activated caspase-8, and activated caspase-3 (Fas-dependent apoptotic pathway) as well as Bad, activated caspase-9 and activated caspase-3 (mitochondria-dependent apoptotic pathway), endonuclease G (EndoG), apoptosis-inducing factor (AIF), and TUNEL-positive apoptosis. The superoxide anion scavenger increased IGF-1, IGF-1R, p-PI3k, p-Akt, p-Bad, Bcl-2, and Bcl-xL (survival pathway). Our findings imply that the superoxide anion scavenger might prevent cardiac Fas-mediated and mitochondrial-mediated apoptosis and enhance the IGF-1-related survival pathway in chronic intermittent hypoxia. The superoxide anion scavenger may prevent chronic sleep apnea-enhanced cardiac apoptotic pathways and enhances

Impulsive EUV bursts observed in C IV with OSO-8

International Nuclear Information System (INIS)

Grant Athay, R.; White, O.R.; Lites, B.W.

1980-01-01

Time sequences of profiles of the lambda 1548 line of C IV containing 51 EUV bursts observed in or near active regions are analyzed to determine the brightness. Doppler shift and line broadening characteristics of the bursts. The bursts have mean lifetimes of approximately 150s, and mean increases in brightness at burst maximum of four-fold as observed with a field of view of 2'' x 20''. Mean burst diameters are estimated to be 3'', or smaller. All but three of the bursts show Doppler shift with velocities sometimes exceeding 75 km s -1 ; 31 are dominated by red shifts and 17 are dominated by blue shifts. Approximately half of the latter group have red-shifted precursors. We interpret the bursts as prominence material, such as surges and coronal rain, moving through the field of view of the spectrometer. (orig.)

Multiparameter Monitoring and Prevention of Fault-Slip Rock Burst

OpenAIRE

Hu, Shan-chao; Tan, Yun-liang; Ning, Jian-guo; Guo, Wei-Yao; Liu, Xue-sheng

2017-01-01

Fault-slip rock burst is one type of the tectonic rock burst during mining. A detailed understanding of the precursory information of fault-slip rock burst and implementation of monitoring and early warning systems, as well as pressure relief measures, are essential to safety production in deep mines. This paper first establishes a mechanical model of stick-slip instability in fault-slip rock bursts and then reveals the failure characteristics of the instability. Then, change rule of mining-i...

PHYSICAL CONSTRAINTS ON FAST RADIO BURSTS

Energy Technology Data Exchange (ETDEWEB)

Luan, Jing; Goldreich, Peter, E-mail: jingluan@caltech.edu [California Institute of Technology, Pasadena, CA 91125 (United States)

2014-04-20

Fast radio bursts (FRBs) are isolated, ms radio pulses with dispersion measure (DM) of order 10{sup 3} pc cm{sup –3}. Galactic candidates for the DM of high latitude bursts detected at GHz frequencies are easily dismissed. DM from bursts emitted in stellar coronas are limited by free-free absorption and those from H II regions are bounded by the nondetection of associated free-free emission at radio wavelengths. Thus, if astronomical, FRBs are probably extragalactic. FRB 110220 has a scattering tail of ∼5.6 ± 0.1 ms. If the electron density fluctuations arise from a turbulent cascade, the scattering is unlikely to be due to propagation through the diffuse intergalactic plasma. A more plausible explanation is that this burst sits in the central region of its host galaxy. Pulse durations of order ms constrain the sizes of FRB sources implying high brightness temperatures that indicates coherent emission. Electric fields near FRBs at cosmological distances would be so strong that they could accelerate free electrons from rest to relativistic energies in a single wave period.

PHYSICAL CONSTRAINTS ON FAST RADIO BURSTS

International Nuclear Information System (INIS)

Luan, Jing; Goldreich, Peter

2014-01-01

Fast radio bursts (FRBs) are isolated, ms radio pulses with dispersion measure (DM) of order 10 3 pc cm –3 . Galactic candidates for the DM of high latitude bursts detected at GHz frequencies are easily dismissed. DM from bursts emitted in stellar coronas are limited by free-free absorption and those from H II regions are bounded by the nondetection of associated free-free emission at radio wavelengths. Thus, if astronomical, FRBs are probably extragalactic. FRB 110220 has a scattering tail of ∼5.6 ± 0.1 ms. If the electron density fluctuations arise from a turbulent cascade, the scattering is unlikely to be due to propagation through the diffuse intergalactic plasma. A more plausible explanation is that this burst sits in the central region of its host galaxy. Pulse durations of order ms constrain the sizes of FRB sources implying high brightness temperatures that indicates coherent emission. Electric fields near FRBs at cosmological distances would be so strong that they could accelerate free electrons from rest to relativistic energies in a single wave period

Phase change based cooling for high burst mode heat loads with temperature regulation above the phase change temperature

Science.gov (United States)

The United States of America as represented by the United States Department of Energy

2009-12-15

An apparatus and method for transferring thermal energy from a heat load is disclosed. In particular, use of a phase change material and specific flow designs enables cooling with temperature regulation well above the fusion temperature of the phase change material for medium and high heat loads from devices operated intermittently (in burst mode). Exemplary heat loads include burst mode lasers and laser diodes, flight avionics, and high power space instruments. Thermal energy is transferred from the heat load to liquid phase change material from a phase change material reservoir. The liquid phase change material is split into two flows. Thermal energy is transferred from the first flow via a phase change material heat sink. The second flow bypasses the phase change material heat sink and joins with liquid phase change material exiting from the phase change material heat sink. The combined liquid phase change material is returned to the liquid phase change material reservoir. The ratio of bypass flow to flow into the phase change material heat sink can be varied to adjust the temperature of the liquid phase change material returned to the liquid phase change material reservoir. Varying the flowrate and temperature of the liquid phase change material presented to the heat load determines the magnitude of thermal energy transferred from the heat load.

Thalamic neuron models encode stimulus information by burst-size modulation

Directory of Open Access Journals (Sweden)

Daniel Henry Elijah

2015-09-01

Full Text Available Thalamic neurons have been long assumed to fire in tonic mode during perceptive states, and in burst mode during sleep and unconsciousness. However, recent evidence suggests that bursts may also be relevant in the encoding of sensory information. Here we explore the neural code of such thalamic bursts. In order to assess whether the burst code is generic or whether it depends on the detailed properties of each bursting neuron, we analyzed two neuron models incorporating different levels of biological detail. One of the models contained no information of the biophysical processes entailed in spike generation, and described neuron activity at a phenomenological level. The second model represented the evolution of the individual ionic conductances involved in spiking and bursting, and required a large number of parameters. We analyzed the models' input selectivity using reverse correlation methods and information theory. We found that n-spike bursts from both models transmit information by modulating their spike count in response to changes to instantaneous input features, such as slope, phase, amplitude, etc. The stimulus feature that is most efficiently encoded by bursts, however, need not coincide with one of such classical features. We therefore searched for the optimal feature among all those that could be expressed as a linear transformation of the time-dependent input current. We found that bursting neurons transmitted 6 times more information about such more general features. The relevant events in the stimulus were located in a time window spanning ~100 ms before and ~20 ms after burst onset. Most importantly, the neural code employed by the simple and the biologically realistic models was largely the same, implying that the simple thalamic neuron model contains the essential ingredients that account for the computational properties of the thalamic burst code. Thus, our results suggest the n-spike burst code is a general property of

Thalamic neuron models encode stimulus information by burst-size modulation.

Science.gov (United States)

Elijah, Daniel H; Samengo, Inés; Montemurro, Marcelo A

2015-01-01

Thalamic neurons have been long assumed to fire in tonic mode during perceptive states, and in burst mode during sleep and unconsciousness. However, recent evidence suggests that bursts may also be relevant in the encoding of sensory information. Here, we explore the neural code of such thalamic bursts. In order to assess whether the burst code is generic or whether it depends on the detailed properties of each bursting neuron, we analyzed two neuron models incorporating different levels of biological detail. One of the models contained no information of the biophysical processes entailed in spike generation, and described neuron activity at a phenomenological level. The second model represented the evolution of the individual ionic conductances involved in spiking and bursting, and required a large number of parameters. We analyzed the models' input selectivity using reverse correlation methods and information theory. We found that n-spike bursts from both models transmit information by modulating their spike count in response to changes to instantaneous input features, such as slope, phase, amplitude, etc. The stimulus feature that is most efficiently encoded by bursts, however, need not coincide with one of such classical features. We therefore searched for the optimal feature among all those that could be expressed as a linear transformation of the time-dependent input current. We found that bursting neurons transmitted 6 times more information about such more general features. The relevant events in the stimulus were located in a time window spanning ~100 ms before and ~20 ms after burst onset. Most importantly, the neural code employed by the simple and the biologically realistic models was largely the same, implying that the simple thalamic neuron model contains the essential ingredients that account for the computational properties of the thalamic burst code. Thus, our results suggest the n-spike burst code is a general property of thalamic neurons.

Coronal mass ejections and solar radio bursts

International Nuclear Information System (INIS)

Kundu, M.R.

1990-01-01

The properties of coronal mass ejection (CME) events and their radio signatures are discussed. These signatures are mostly in the form of type II and type IV burst emissions. Although type II bursts are temporally associated with CMEs, it is shown that there is no spatial relationship between them. Type II's associated with CMEs have in most cases a different origin, and they are not piston-driven by CMEs. Moving type IV and type II bursts can be associated with slow CMEs with speeds as low as 200 km/s, contrary to the earlier belief that only CMEs with speeds >400 km/s are associated with radio bursts. A specific event has been discussed in which the CME and type IV burst has nearly the same speed and direction, but the type II burst location was behind the CME and its motion was transverse. The speed and motion of the type II burst strongly suggest that the type II shock was decoupled from the CME and was probably due to a flare behind the limb. Therefore only the type IV source could be directly associated with the slow CME. The electrons responsble for the type IV emission could be produced in the flare or in the type II and then become trapped in a plasmoid associated with the CME. The reconnected loop could then move outwards as in the usual palsmoid model. Alternatively, the type IV emission could be interpreted as due to electrons produced by acceleration in wave turbulence driven by currents in the shock front driven by the CME. The lower-hybrid model Lampe and Papadopoulos (1982), which operates at both fast and slow mode shocks, could be applied to this situation. (author). 31 refs., 12 figs

Characterization of intermittency in zooplankton behaviour in turbulence.

Science.gov (United States)

Michalec, François-Gaël; Schmitt, François G; Souissi, Sami; Holzner, Markus

2015-10-01

We consider Lagrangian velocity differences of zooplankters swimming in still water and in turbulence. Using cumulants, we quantify the intermittency properties of their motion recorded using three-dimensional particle tracking velocimetry. Copepods swimming in still water display an intermittent behaviour characterized by a high probability of small velocity increments, and by stretched exponential tails. Low values arise from their steady cruising behaviour while heavy tails result from frequent relocation jumps. In turbulence, we show that at short time scales, the intermittency signature of active copepods clearly differs from that of the underlying flow, and reflects the frequent relocation jumps displayed by these small animals. Despite these differences, we show that copepods swimming in still and turbulent flow belong to the same intermittency class that can be modelled by a log-stable model with non-analytical cumulant generating function. Intermittency in swimming behaviour and relocation jumps may enable copepods to display oriented, collective motion under strong hydrodynamic conditions and thus, may contribute to the formation of zooplankton patches in energetic environments.

ARE ULTRA-LONG GAMMA-RAY BURSTS DIFFERENT?

Energy Technology Data Exchange (ETDEWEB)

Boër, M.; Gendre, B. [CNRS-ARTEMIS, Boulevard de l' Observatoire, CS 34229, 06304 Nice Cedex 4 (France); Stratta, G., E-mail: michel.boer@unice.fr [Università degli Studi di Urbino Carlo Bo, I-61029 Urbino (Italy)

2015-02-10

The discovery of a number of gamma-ray bursts (GRBs) with duration exceeding 1000 s has opened the debate on whether these bursts form a new class of sources, the so-called ultra-long GRBs, or if they are rather the tail of the distribution of the standard long GRB duration. Using the long GRB sample detected by Swift, we investigate the statistical properties of long GRBs and compare them with the ultra-long burst properties. We compute the burst duration of long GRBs using the start epoch of the so-called ''steep decay'' phase detected with Swift/XRT. We discuss also the differences observed in their spectral properties. We find that ultra-long GRBs are statistically different from the standard long GRBs with typical burst duration less than 100-500 s, for which a Wolf-Rayet star progenitor is usually invoked. Together with the presence of a thermal emission component we interpret this result as indication that the usual long GRB progenitor scenario cannot explain the extreme duration of ultra-long GRBs, their energetics, as well as the mass reservoir and size that can feed the central engine for such a long time.

On Burst Detection and Prediction in Retweeting Sequence

Science.gov (United States)

2015-05-22

We conduct a comprehensive empirical analysis of a large microblogging dataset collected from the Sina Weibo and report our observations of burst...whether and how accurate we can predict bursts using classifiers based on the extracted features. Our empirical study of the Sina Weibo data shows the...feasibility of burst prediction using appropriately extracted features and classic classifiers. 1 Introduction Microblogging, such as Twitter and Sina

LAT Onboard Science: Gamma-Ray Burst Identification

International Nuclear Information System (INIS)

Kuehn, Frederick; Hughes, Richard; Smith, Patrick; Winer, Brian; Bonnell, Jerry; Norris, Jay; Ritz, Steven; Russell, James

2007-01-01

The main goal of the Large Area Telescope (LAT) onboard science program is to provide quick identification and localization of Gamma Ray Bursts (GRB) onboard the LAT for follow-up observations by other observatories. The GRB identification and localization algorithm will provide celestial coordinates with an error region that will be distributed via the Gamma ray burst Coordinate Network (GCN). We present results that show our sensitivity to bursts as characterized using Monte Carlo simulations of the GLAST observatory. We describe and characterize the method of onboard track determination and the GRB identification and localization algorithm. Onboard track determination is considerably different than in the on-ground case, resulting in a substantially altered point spread function. The algorithm contains tunable parameters which may be adjusted after launch when real bursts characteristics at very high energies have been identified

Gamma-ray burst polarimeter (GAP)

International Nuclear Information System (INIS)

Mihara, Tatehiro; Murakami, Toshio; Yonetoku, Daisuke; Gunji, Shuichi; Kubo, Shin

2013-01-01

The gamma-ray burst polarimeter (GAP: GAmma-ray burst Polarimeter), which had been almost handcrafted by scientists, has succeeded in working normally in interplanetary space, and in detecting the polarization of the gamma-ray from a mysterious astronomical object 'gamma-ray burst'. It is the first result of the detectors in the world exclusively aiming at detecting gamma-ray polarization. We mainly describe the hardware of our GAP equipment and show the method of preparing equipment to work in the cosmic space with a tight budget. The mechanical structure, the electronic circuits, the software on the equipment, the data analysis on the earth, and the scientific results gained by the observation just over one year, are presented after explaining the principle of gamma-ray polarization detection. Our design to protect equipment against mechanical shock and cosmic radiation may provide useful information for future preparation of compact satellite. (J.P.N.)

Multifrequency Observations of Gamma-Ray Burst

OpenAIRE

Greiner, J.

1995-01-01

Neither a flaring nor a quiescent counterpart to a gamma-ray burst has yet been convincingly identified at any wavelength region. The present status of the search for counterparts of classical gamma-ray bursts is given. Particular emphasis is put on the search for flaring counterparts, i.e. emission during or shortly after the gamma-ray emission.

Gamma Ray Bursts and the Birth of Black Holes

Science.gov (United States)

Gehrels, Neil

2009-01-01

Black holes have been predicted since the 1940's from solutions of Einstein's general relativity field equation. There is strong evidence of their existence from astronomical observations, but their origin has remained an open question of great interest. Gamma-ray bursts may the clue. They are powerful explosions, visible to high redshift, and appear to be the birth cries of black holes. The Swift and Fermi missions are two powerful NASA observatories currently in orbit that are discovering how gamma-ray bursts work. Evidence is building that the long and short duration subcategories of GRBs have very different origins: massive star core collapse to a black hole for long bursts and binary neutron star coalescence to a black hole for short bursts. The similarity to Type II and Ia supernovae originating from young and old stellar progenitors is striking. Bursts are tremendously luminous and are providing a new tool to study the high redshift universe. One Swift burst at z=8.3 is the most distant object known in the universe. The talk will present the latest gamma-ray burst results from Swift and Fermi and will highlight what they are teaching us about black holes and jet outflows.

Observational properties of cosmic gamma-ray bursts

International Nuclear Information System (INIS)

Mazets, E.P.

1986-01-01

A brief overview of the major observational results obtained in gamma-ray burst studies is presented. Also discussed is to what extent the thermonuclear model, which appears at present to be the most plausible, can account for the observed properties of the bursts. The investigation of gamma-ray bursts should cover observations of the time histories of events, energy spectra, and their variablility, source localization, and inspection of the localization regions during the active and quiescent phases of the source in other wavelengths, as well as, evaluation of the statistical distributions of the data obtained

Heuristic burst detection method using flow and pressure measurements

NARCIS (Netherlands)

Bakker, M.; Vreeburg, J.H.G.; Roer, Van de M.; Rietveld, L.C.

2014-01-01

Pipe bursts in a drinking water distribution system lead to water losses, interruption of supply, and damage to streets and houses due to the uncontrolled water flow. To minimize the negative consequences of pipe bursts, an early detection is necessary. This paper describes a heuristic burst

IGR J17254-3257, a new bursting neutron star

DEFF Research Database (Denmark)

Chenevez, Jérôme; Falanga, M.; Kuulkers, E.

2007-01-01

Aims. The study of the observational properties of uncommonly long bursts from low luminosity sources is important when investigating the transition from a hydrogen - rich bursting regime to a pure helium regime and from helium burning to carbon burning as predicted by current burst theories. On ...

The development of a burst criterion for zircaloy fuel cladding under LOCA conditions

International Nuclear Information System (INIS)

Neitzel, H.J.; Rossinger, H.E.

1980-02-01

A burst criterion model, which assumes that deformation is controlled by steady-state creep, has been developed for a thin-walled cladding, in this case Zircaloy-4, subjected to a differential pressure and high temperature. The creep equation is integrated to obtain a burst time at the singularity of the strain. Once the burst time is known, the burst temperature and burst pressure can be calculated from the known temperature and pressure histories. A further relationship between burst stress and burst temperature is used to calculate the burst strain. Comparison with measured burst data shows good agreement between theory and experiment was found that, if the heating rate is constant, the burst temperature increases with decreasing stress, and that, if the stress level is constant, the burst temperature increases with increasing heating rate. It was also found that anisotropy alters the burst temperature and burst strain, and that test conditions in the α-Zr temperature range have no influence on the burst data. (auth)

Bursts generate a non-reducible spike-pattern code

Directory of Open Access Journals (Sweden)

Hugo G Eyherabide

2009-05-01

Full Text Available On the single-neuron level, precisely timed spikes can either constitute firing-rate codes or spike-pattern codes that utilize the relative timing between consecutive spikes. There has been little experimental support for the hypothesis that such temporal patterns contribute substantially to information transmission. Using grasshopper auditory receptors as a model system, we show that correlations between spikes can be used to represent behaviorally relevant stimuli. The correlations reflect the inner structure of the spike train: a succession of burst-like patterns. We demonstrate that bursts with different spike counts encode different stimulus features, such that about 20% of the transmitted information corresponds to discriminating between different features, and the remaining 80% is used to allocate these features in time. In this spike-pattern code, the "what" and the "when" of the stimuli are encoded in the duration of each burst and the time of burst onset, respectively. Given the ubiquity of burst firing, we expect similar findings also for other neural systems.

Internally consistent gamma ray burst time history phenomenology

International Nuclear Information System (INIS)

Cline, T.L.

1985-01-01

A phenomenology for gamma ray burst time histories is outlined. Order of their generally chaotic appearance is attempted, based on the speculation that any one burst event can be represented above 150 keV as a superposition of similarly shaped increases of varying intensity. The increases can generally overlap, however, confusing the picture, but a given event must at least exhibit its own limiting characteristic rise and decay times if the measurements are made with instruments having adequate temporal resolution. Most catalogued observations may be of doubtful or marginal utility to test this hypothesis, but some time histories from Helios-2, Pioneer Venus Orbiter and other instruments having one-to several-millisecond capabilities appear to provide consistency. Also, recent studies of temporally resolved Solar Maximum Mission burst energy spectra are entirely compatible with this picture. The phenomenology suggested here, if correct, may assist as an analytic tool for modelling of burst processes and possibly in the definition of burst source populations

Demonstration of a viable quantitative theory for interplanetary type II radio bursts

Energy Technology Data Exchange (ETDEWEB)

Schmidt, J. M., E-mail: jschmidt@physics.usyd.edu.au; Cairns, Iver H. [School of Physics, Physics Road, Building A28, University of Sydney, NSW 2006 (Australia)

2016-03-25

Between 29 November and 1 December 2013 the two widely separated spacecraft STEREO A and B observed a long lasting, intermittent, type II radio burst for the extended frequency range ≈ 4 MHz to 30 kHz, including an intensification when the shock wave of the associated coronal mass ejection (CME) reached STEREO A. We demonstrate for the first time our ability to quantitatively and accurately simulate the fundamental (F) and harmonic (H) emission of type II bursts from the higher corona (near 11 solar radii) to 1 AU. Our modeling requires the combination of data-driven three-dimensional magnetohydrodynamic simulations for the CME and plasma background, carried out with the BATS-R-US code, with an analytic quantitative kinetic model for both F and H radio emission, including the electron reflection at the shock, growth of Langmuir waves and radio waves, and the radiations propagation to an arbitrary observer. The intensities and frequencies of the observed radio emissions vary hugely by factors ≈ 10{sup 6} and ≈ 10{sup 3}, respectively; the theoretical predictions are impressively accurate, being typically in error by less than a factor of 10 and 20 %, for both STEREO A and B. We also obtain accurate predictions for the timing and characteristics of the shock and local radio onsets at STEREO A, the lack of such onsets at STEREO B, and the z-component of the magnetic field at STEREO A ahead of the shock, and in the sheath. Very strong support is provided by these multiple agreements for the theory, the efficacy of the BATS-R-US code, and the vision of using type IIs and associated data-theory iterations to predict whether a CME will impact Earth’s magnetosphere and drive space weather events.

What can NuSTAR do for X-ray bursts?

DEFF Research Database (Denmark)

Chenevez, Jérôme; Tomsick, John; Chakrabarty, Deepto

2012-01-01

burning are ejected in the burst expansion wind. We have investigated the possibility of observing with NuSTAR some X-ray bursters selected for their high burst rate and trend to exhibit so-called superexpansion bursts. Our main ambition is to detect the photoionization edges associated with the ejected...

Effect of wear on the burst strength of l-80 steel casing

International Nuclear Information System (INIS)

Irawan, S; Bharadwaj, A M; Temesgen, B; Karuppanan, S; Abdullah, M Z B

2015-01-01

Casing wear has recently become one of the areas of research interest in the oil and gas industry especially in extended reach well drilling. The burst strength of a worn out casing is one of the significantly affected mechanical properties and is yet an area where less research is done The most commonly used equations to calculate the resulting burst strength after wear are Barlow, the initial yield burst, the full yield burst and the rupture burst equations. The objective of this study was to estimate casing burst strength after wear through Finite Element Analysis (FEA). It included calculation and comparison of the different theoretical bursts pressures with the simulation results along with effect of different wear shapes on L-80 casing material. The von Misses stress was used in the estimation of the burst pressure. The result obtained shows that the casing burst strength decreases as the wear percentage increases. Moreover, the burst strength value of the casing obtained from the FEA has a higher value compared to the theoretical burst strength values. Casing with crescent shaped wear give the highest burst strength value when simulated under nonlinear analysis. (paper)

Bubble bursting at an interface

Science.gov (United States)

Kulkarni, Varun; Sajjad, Kumayl; Anand, Sushant; Fezzaa, Kamel

2017-11-01

Bubble bursting is crucial to understanding the life span of bubbles at an interface and more importantly the nature of interaction between the bulk liquid and the outside environment from the point of view of chemical and biological material transport. The dynamics of the bubble as it rises from inside the liquid bulk to its disappearance on the interface after bursting is an intriguing process, many aspects of which are still being explored. In our study, we make detailed high speed imaging measurements to examine carefully the hole initiation and growth in bursting bubbles that unearth some interesting features of the process. Previous analyses available in literature are revisited based on our novel experimental visualizations. Using a combination of experiments and theory we investigate the role of various forces during the rupturing process. This work aims to further our current knowledge of bubble dynamics at an interface with an aim of predicting better the bubble evolution from its growth to its eventual integration with the liquid bulk.

The effects of individualized theta burst stimulation on the excitability of the human motor system.

Science.gov (United States)

Brownjohn, Philip W; Reynolds, John N J; Matheson, Natalie; Fox, Jonathan; Shemmell, Jonathan B H

2014-01-01

Theta burst stimulation (TBS) is a pattern of repetitive transcranial magnetic stimulation that has been demonstrated to facilitate or suppress human corticospinal excitability when applied intermittently (iTBS) or continuously (cTBS), respectively. While the fundamental pattern of TBS, consisting of bursts of 50 Hz stimulation repeated at a 5 Hz theta frequency, induces synaptic plasticity in animals and in vitro preparations, the relationship between TBS and underlying cortical firing patterns in the human cortex has not been elucidated. To compare the effects of 5 Hz iTBS and cTBS with individualized TBS paradigms on corticospinal excitability and intracortical inhibitory circuits. Participants received standard and individualized iTBS (iTBS 5; iTBS I) and cTBS (cTBS 5; cTBS I), and sham TBS, in a randomised design. For individualized paradigms, the 5 Hz theta component of the TBS pattern was replaced by the dominant cortical frequency (4-16 Hz; upper frequency restricted by technical limitations) for each individual. We report that iTBS 5 and iTBS I both significantly facilitated motor evoked potential (MEP) amplitude to a similar extent. Unexpectedly, cTBS 5 and cTBS I failed to suppress MEP amplitude. None of the active TBS protocols had any significant effects on intracortical circuits when compared with sham TBS. In summary, iTBS facilitated MEP amplitude, an effect that was not improved by individualizing the theta component of the TBS pattern, while cTBS, a reportedly inhibitory paradigm, produced no change, or facilitation of MEP amplitude in our hands. Copyright © 2014 Elsevier Inc. All rights reserved.

Which factors make clean intermittent (self) catheterisation successful?

NARCIS (Netherlands)

Cobussen-Boekhorst, H.; Beekman, J.; Wijlick, E. van; Schaafstra, J.; Kuppevelt, D. van; Heesakkers, J.P.

2016-01-01

AIMS AND OBJECTIVES: To explore which factors determine successful intermittent catheterisation. BACKGROUND: Intermittent catheterisation is a safe, effective treatment and is associated with improved quality of life, although negative issues are reported. Factors which determine adherence are

The development of a burst criterion for Zircaloy fuel cladding under LOCA conditions

International Nuclear Information System (INIS)

Neitzel, H.J.; Rosinger, H.E.

1980-10-01

A burst criterion model, which assumes that deformation is controlled by steady-state creep, has been developed for a thin-walled cladding, in this case Zircaloy-4, subjected to a differential pressure and high temperature. The creep equation is integrated to obtain a burst time at the singularity of the strain. Once that urst time is known, the burst temperature and burst pressure can be calculated from the known temperature and pressure histories. A further relationship between burst stress and burst temperature is used to calculate the burst strain. Comparison with measured burst data shows good agreement between theory and experiment. It was found that, if the heating rate is constant, the burst temperature increases with decreasing stress, and that, if the stress level is constant, the burst temperature increases with increasing heating rate. It was also found that anisotropy alters the burst temperature and burst strain, and that thest conditions in the α-Zr temperature range have no influence on the burst data. (orig.) [de

Stimulus-dependent modulation of spike burst length in cat striate cortical cells.

Science.gov (United States)

DeBusk, B C; DeBruyn, E J; Snider, R K; Kabara, J F; Bonds, A B

1997-07-01

Burst activity, defined by groups of two or more spikes with intervals of cats. Bursting varied broadly across a population of 507 simple and complex cells. Half of this population had > or = 42% of their spikes contained in bursts. The fraction of spikes in bursts did not vary as a function of average firing rate and was stationary over time. Peaks in the interspike interval histograms were found at both 3-5 ms and 10-30 ms. In many cells the locations of these peaks were independent of firing rate, indicating a quantized control of firing behavior at two different time scales. The activity at the shorter time scale most likely results from intrinsic properties of the cell membrane, and that at the longer scale from recurrent network excitation. Burst frequency (bursts per s) and burst length (spikes per burst) both depended on firing rate. Burst frequency was essentially linear with firing rate, whereas burst length was a nonlinear function of firing rate and was also governed by stimulus orientation. At a given firing rate, burst length was greater for optimal orientations than for nonoptimal orientations. No organized orientation dependence was seen in bursts from lateral geniculate nucleus cells. Activation of cortical contrast gain control at low response amplitudes resulted in no burst length modulation, but burst shortening at optimal orientations was found in responses characterized by supersaturation. At a given firing rate, cortical burst length was shortened by microinjection of gamma-aminobutyric acid (GABA), and bursts became longer in the presence of N-methyl-bicuculline, a GABA(A) receptor blocker. These results are consistent with a model in which responses are reduced at nonoptimal orientations, at least in part, by burst shortening that is mediated by GABA. A similar mechanism contributes to response supersaturation at high contrasts via recruitment of inhibitory responses that are tuned to adjacent orientations. Burst length modulation can serve

Voltage interval mappings for an elliptic bursting model

OpenAIRE

Wojcik, Jeremy; Shilnikov, Andrey

2013-01-01

We employed Poincar\\'e return mappings for a parameter interval to an exemplary elliptic bursting model, the FitzHugh-Nagumo-Rinzel model. Using the interval mappings, we were able to examine in detail the bifurcations that underlie the complex activity transitions between: tonic spiking and bursting, bursting and mixed-mode oscillations, and finally, mixed-mode oscillations and quiescence in the FitzHugh-Nagumo-Rinzel model. We illustrate the wealth of information, qualitative and quantitati...

Supernova sheds light on gamma-ray bursts

CERN Multimedia

2003-01-01

On 29 March the HETE-II satellite detected the most violent explosion in the universe to date - an enormous burst of gamma rays. Observers across the world recorded and studied the event. It appears to prove that gamma ray bursts originate in supernovae (1 page)

Observation of L-bursts of Jupiter decameter waves

International Nuclear Information System (INIS)

Imai, Kazumasa; Tomisawa, Ichiro

1978-01-01

The Jupiter decameter waves are the only information source which can be obtained on the earth for the investigation of dynamics concerning the generation of plasma waves in the magnetosphere of Jupiter. The emission of Jupiter decameter waves is modulated by the satellite Io considerably. It is observed that the emission of decameter waves fluctuated much in course of time. The duration time of bursts is 1 to 10 sec and 1 to 50 msec for L-bursts and S-bursts, respectively. The simultaneous observations were conducted at two locations from August, 1977, and at three locations from December, 1977, for searching the source of L-bursts. The relation between the appearance frequency of L-bursts and S-bursts and Io phase and system 3 longitude is explained. The observation points were Sugadaira, Chofu and Toyokawa, The minimum detectable flux density by the wave receiving network is 10 -21 W/m 2 .Hz. Concerning the observed results, the locations of observed events on the Io phase and the system 3 longitude are shown. The analytical results on the L-bursts of the main source and the early source are explained, taking ten events. The analysed dynamic cross-correlation and the spectrum analysis of the decameter intensity are shown. The relation between the origin and the emission mechanism was investigated, considering the observed data and the evaluation mentioned above for the main source and early source, and the clue was obtained to solve the riddle of emission mechanism. (Nakai, Y.)

Detection of gamma-ray bursts from Andromeda

International Nuclear Information System (INIS)

Bulik, Tomasz; Coppi, Paolo S.; Lamb, Donald Q.

1996-01-01

If gamma-ray bursts originate in a corona around the Milky Way, it should also be possible to detect them from a similar corona around Andromeda. Adopting a simple model of high velocity neutron star corona, we evaluate the ability of instruments on existing missions to detect an excess of bursts toward Andromeda. We also calculate the optimal properties of an instrument designed to detect such an excess. We find that if the bursts radiate isotropically, an experiment with a sampling distance d max > or approx. 500 kpc could detect a significant excess of bursts in the direction of Andromeda in a few years of observation. If the radiation is beamed along the neutron star's direction of motion, an experiment with d max > or approx. 800 kpc would detect such an excess in a similar amount of time, provided that the width of the beam is greater than 10 deg. Lack of an excess toward Andromeda would therefore be compelling evidence that the bursts are cosmological in origin if made by an instrument at least 50 times more sensitive than BATSE, given current constraints on Galactic corona models. Comparisons with detailed dynamical calculations of the spatial distribution of high velocity neutron stars in the coronae around the Milky Way and Andromeda confirm these conclusions

Scientific Applications Performance Evaluation on Burst Buffer

KAUST Repository

Markomanolis, George S.

2017-10-19

Parallel I/O is an integral component of modern high performance computing, especially in storing and processing very large datasets, such as the case of seismic imaging, CFD, combustion and weather modeling. The storage hierarchy includes nowadays additional layers, the latest being the usage of SSD-based storage as a Burst Buffer for I/O acceleration. We present an in-depth analysis on how to use Burst Buffer for specific cases and how the internal MPI I/O aggregators operate according to the options that the user provides during his job submission. We analyze the performance of a range of I/O intensive scientific applications, at various scales on a large installation of Lustre parallel file system compared to an SSD-based Burst Buffer. Our results show a performance improvement over Lustre when using Burst Buffer. Moreover, we show results from a data hierarchy library which indicate that the standard I/O approaches are not enough to get the expected performance from this technology. The performance gain on the total execution time of the studied applications is between 1.16 and 3 times compared to Lustre. One of the test cases achieved an impressive I/O throughput of 900 GB/s on Burst Buffer.

[Effect of intermittent fasting on physiology and gut microbiota in presenium rats].

Science.gov (United States)

Rong, Zu-Hua; Liang, Shao-Cong; Lu, Jun-Qi; He, Yan; Luo, Yue-Mei; You, Chao; Xia, Geng-Hong; M, Prabhakar; Li, Pan; Zhou, Hong-Wei

2016-04-20

To investigate the effect of intermittent fasting on metabolize and gut microbiota in obese presenium rats fed with high-fat-sugar-diet. We fed the Wistar rats with high-fat and high-sugar diet to induce adiposity, and the rats for intermittent fasting were selected base on their body weight. The rats were subjected to fasting for 72 h every 2 weeks for 18 weeks. OGTT test was performed and fasting blood samples and fecal samples were collected for measurement of TC, TG, HDL-C and LDL-C and sequence analysis of fecal 16S rRNA V4 tags using Illumina. Gut microbial community structure was analyzed with QIIME and LEfSe. After the intervention, the body weight of the fasting rats was significantly lower than that in high-fat diet group (P<0.01). OGTT results suggested impairment of sugar tolerance in the fasting group, which showed a significantly larger AUC than compared with the high-fat diet group (P<0.05). Intermittent fasting significantly reduced blood HDL-C and LDL-C levels (P<0.05) and partially restored liver steatosis, and improved the gut microbiota by increasing the abundance of YS2, RF32 and Helicobacteraceae and reducing Lactobacillus, Roseburia, Erysipelotrichaceae and Ralstonia. Bradyrhizobiaceae was found to be positively correlated with CHOL and HDL-C, and RF39 was inversely correlated with the weight of the rats. Intermittent fasting can decrease the body weight and blood lipid levels and restore normal gut microbiota but can cause impairment of glucose metabolism in obese presenium rats.

Photonic integrated circuits unveil crisis-induced intermittency.

Science.gov (United States)

Karsaklian Dal Bosco, Andreas; Akizawa, Yasuhiro; Kanno, Kazutaka; Uchida, Atsushi; Harayama, Takahisa; Yoshimura, Kazuyuki

2016-09-19

We experimentally investigate an intermittent route to chaos in a photonic integrated circuit consisting of a semiconductor laser with time-delayed optical feedback from a short external cavity. The transition from a period-doubling dynamics to a fully-developed chaos reveals a stage intermittently exhibiting these two dynamics. We unveil the bifurcation mechanism underlying this route to chaos by using the Lang-Kobayashi model and demonstrate that the process is based on a phenomenon of attractor expansion initiated by a particular distribution of the local Lyapunov exponents. We emphasize on the crucial importance of the distribution of the steady-state solutions introduced by the time-delayed feedback on the existence of this intermittent dynamics.

Chaos synchronization based on intermittent state observer

Institute of Scientific and Technical Information of China (English)

Li Guo-Hui; Zhou Shi-Ping; Xu De-Ming

2004-01-01

This paper describes the method of synchronizing slave to the master trajectory using an intermittent state observer by constructing a synchronizer which drives the response system globally tracing the driving system asymptotically. It has been shown from the theory of synchronization error-analysis that a satisfactory result of chaos synchronization is expected under an appropriate intermittent period and state observer. Compared with continuous control method,the proposed intermittent method can target the desired orbit more efficiently. The application of the method is demonstrated on the hyperchaotic Rossler systems. Numerical simulations show that the length of the synchronization interval rs is of crucial importance for our scheme, and the method is robust with respect to parameter mismatch.

Controls on streamflow intermittence in the Colorado Front Range

Science.gov (United States)

Kampf, S. K.; Puntenney, K.; Martin, C.; Weber, R.; Gerlich, J.; Hammond, J. C.; Lefsky, M. A.

2017-12-01

Intermittent streams comprise more than 60% of the channel length in semiarid northern Colorado, yet little is known about their flow magnitude and timing. We used field surveys, stream sensors, and remote sensing to quantify spatial and temporal patterns of streamflow intermittence in the Cache la Poudre basin in 2016-2017. To evaluate potential controls on streamflow intermittence, we delineated the drainage area to each monitored point and quantified the catchment's mean precipitation, temperature, snow persistence, slope, aspect, vegetation type, soil type, and bedrock geology. During the period of study, most streams below 2500 m elevation and drainage areas >1 km2 had perennial flow, whereas nearly all streams with drainage areas <1 km2 had intermittent flow. For the high elevation intermittent streams, stream locations often differed substantially from the locations mapped in standard GIS data products. Initial analyses have identified no clearly quantifiable controls on flow duration of high elevation streams, but field observations indicate subsurface flow paths are important contributors to surface streams.

Supernovae and Gamma-Ray Bursts : the Greatest Explosions since the Big Bang

CERN Document Server

Panagia, Nino; Sahu, Kailash; Space Telescope Science Institute Symposium

2001-01-01

Since the dramatic discovery that the supernova SN1998bw coincided in position and time with a gamma-ray burst, the possibility was raised that these two types of spectacular explosions are related. This timely volume presents especially written articles by a host of world experts who gathered together for an international conference at the Space Telescope Science Institute. This was the first meeting in which the communities of supernova researchers and gamma-ray burst researchers were brought together to share ideas. The contributions review the mechanisms for these explosive events, the possible connections between them, and their relevance for cosmology. Both observations and theoretical developments are covered. This book is an invaluable source of information for both active researchers and graduate students in this exciting area of research.

Human θ burst stimulation enhances subsequent motor learning and increases performance variability.

Science.gov (United States)

Teo, James T H; Swayne, Orlando B C; Cheeran, Binith; Greenwood, Richard J; Rothwell, John C

2011-07-01

Intermittent theta burst stimulation (iTBS) transiently increases motor cortex excitability in healthy humans by a process thought to involve synaptic long-term potentiation (LTP), and this is enhanced by nicotine. Acquisition of a ballistic motor task is likewise accompanied by increased excitability and presumed intracortical LTP. Here, we test how iTBS and nicotine influences subsequent motor learning. Ten healthy subjects participated in a double-blinded placebo-controlled trial testing the effects of iTBS and nicotine. iTBS alone increased the rate of learning but this increase was blocked by nicotine. We then investigated factors other than synaptic strengthening that may play a role. Behavioral analysis and modeling suggested that iTBS increased performance variability, which correlated with learning outcome. A control experiment confirmed the increase in motor output variability by showing that iTBS increased the dispersion of involuntary transcranial magnetic stimulation-evoked thumb movements. We suggest that in addition to the effect on synaptic plasticity, iTBS may have facilitated performance by increasing motor output variability; nicotine negated this effect on variability perhaps via increasing the signal-to-noise ratio in cerebral cortex.

Physical characterization of the Skua fast burst assembly

International Nuclear Information System (INIS)

Paternoster, R.; Bounds, J.; Sanchez, R.; Miko, D.

1994-01-01

In this paper we discuss the system design and ongoing efforts to characterize the machine physics and operating properties of the Skua fast burst assembly. The machine is currently operating up to prompt critical while we await approval for super-prompt burst operations. Efforts have centered on characterizing neutron kinetic properties, comparing calculated and measured temperature coefficients and power distributions, improving the burst reproducibility, examining the site-wide dose characteristics, and fitting the machine with cooling and filtration systems

Multi-Index Monitoring and Evaluation on Rock Burst in Yangcheng Mine

Directory of Open Access Journals (Sweden)

Yunliang Tan

2015-01-01

Full Text Available Based on the foreboding information monitoring of the energy released in the developing process of rock burst, prediction system for rock burst can be established. By using microseismic method, electromagnetic radiation method, and drilling bits method, rock burst in Yangcheng Mine was monitored, and a system of multi-index monitoring and evaluation on rock burst was established. Microseismic monitoring and electromagnetic radiation monitoring were early warning method, and drilling bits monitoring was burst region identification method. There were three identifying indexes: silence period in microseismic monitoring, rising period of the intensity, and rising period of pulse count in electromagnetic radiation monitoring. If there is identified burst risk in the workface, drilling bits method was used to ascertain the burst region, and then pressure releasing methods were carried out to eliminate the disaster.

Frequency dependent characteristics of solar impulsive radio bursts

International Nuclear Information System (INIS)

Das, T.K.; Das Gupta, M.K.

1983-01-01

An investigation was made of the impulsive radio bursts observed in the frequency range 0.245 to 35 GHz. Important results obtained are: (i) Simple type 1 bursts with intensities 0 to 10 f.u. and simple type 2 bursts with intensities 10 to 500 f.u. are predominant in the frequency ranges 1.415 to 4.995 GHz and 4.995 to 8.8 GHz, respectively; (ii) With maxima around 2.7 GHz and 4 GHz for the first and second types respectively, the durations of the radio bursts decrease gradually both towards lower and higher frequencies; (iii) As regards occurrences, the first type dominates in the southern solar hemisphere peaking around 8.8 GHz, whereas the second type favours the north with no well-defined maximum in any frequency; (iv) Both types prefer the eastern hemisphere, the peak occurrences being around 8.8 GHz and 5 GHz for the two successive types, respectively; (c) The spectra of impulsive radio bursts are generally of the inverted U-type with the maximum emission intensity between 5 and 15 GHz. (author)

Ion burst event in the earth's dayside magnetosheath

International Nuclear Information System (INIS)

Paschalidis, N.P.; Krimigis, S.M.; Sibeck, D.G.; McEntire, R.W.; Zanetti, L.J.; Sarris, E.T.; Christon, S.P.

1991-01-01

The MEPA instrument on the AMPTE/CCE Spacecraft provided ion angular distributions as rapidly as every 6 sec for H, He, and O at energies of 10 keV to 2 MeV in the dayside magnetosheath within 8.75 R E , the CCE apogee. In this report the authors discuss a burst of energetic particles in the subsolar magnetosheath and its association with rapid changes in the local magnetic field direction in such a way that the magnetic field connected the spacecraft to the magnetopause during the enhancement. They find that magnetosheath angular distributions outside the burst peaked at 90 degree pitch angles, whereas during the burst they exhibited field aligned streaming either parallel or antiparallel to the magnetic field combined with a clear earthward gradient. The clear earthward gradients at E ≥ 10 KeV, the streaming, and the slope change in the burst-time magnetosheath spectrum at ∼10 KeV suggest magnetospheric source for the burst-time ≥ 10 KeV ions and heated solar wind for E < 10 KeV

Clinical study of intermittent lock of the temporomandibular joint. Relation to frequency of intermittent lock on clinical examination and magnetic resonance imaging

Energy Technology Data Exchange (ETDEWEB)

Ide, Takashi; Nagai, Itaru; Miyazaki, Akihiro; Yamaguchi, Akira; Kohama, Geniku [Sapporo Medical Univ. (Japan). School of Medicine

2002-03-01

To examine the occurrence of intermittent lock, we investigated the correlation between the frequency of intermittent lock of the temporomandibular joint and magnetic resonance imaging (MRI) findings. The subjects consisted of 25 patients (25 joints) with unilateral intermittent lock who were treated from April 1994 through March 2000 at our department. MRI examination of the joint was performed on the affected side. We divided the patients into two groups: a high-frequency group consisting of 15 patients who had symptoms of intermittent lock every day and a low-frequency group consisting of 10 patients who did not have symptoms every day. The results showed no statistical difference between the two groups in clinical findings such as age, sex, clicking side of the joint, duration of intermittent lock, method of unlocking, muscle pain on palpation, degree of maximal mouth opening, distance between the maxillary and mandibular tooth midline, or the degree of overbite and overjet. However, the two groups differed significantly in the degree of anterior disc displacement as assessed by MRI. (author)

Accelerating Science with the NERSC Burst Buffer Early User Program

Energy Technology Data Exchange (ETDEWEB)

Bhimji, Wahid [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Bard, Debbie [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Romanus, Melissa [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Rutgers Univ., New Brunswick, NJ (United States); Paul, David [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Ovsyannikov, Andrey [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Friesen, Brian [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Bryson, Matt [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Correa, Joaquin [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Lockwood, Glenn K. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Tsulaia, Vakho [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Byna, Suren [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Farrell, Steve [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Gursoy, Doga [Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS); Daley, Chris [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Beckner, Vince [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Van Straalen, Brian [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Trebotich, David [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Tull, Craig [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Weber, Gunther H. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Wright, Nicholas J. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Antypas, Katie [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Prabhat, none [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

2016-01-01

NVRAM-based Burst Buffers are an important part of the emerging HPC storage landscape. The National Energy Research Scientific Computing Center (NERSC) at Lawrence Berkeley National Laboratory recently installed one of the first Burst Buffer systems as part of its new Cori supercomputer, collaborating with Cray on the development of the DataWarp software. NERSC has a diverse user base comprised of over 6500 users in 700 different projects spanning a wide variety of scientific computing applications. The use-cases of the Burst Buffer at NERSC are therefore also considerable and diverse. We describe here performance measurements and lessons learned from the Burst Buffer Early User Program at NERSC, which selected a number of research projects to gain early access to the Burst Buffer and exercise its capability to enable new scientific advancements. To the best of our knowledge this is the first time a Burst Buffer has been stressed at scale by diverse, real user workloads and therefore these lessons will be of considerable benefit to shaping the developing use of Burst Buffers at HPC centers.

Towards an intermittency-friendly energy system: Comparing electric boilers and heat pumps in distributed cogeneration

International Nuclear Information System (INIS)

Blarke, Morten B.

2012-01-01

Highlights: ► We propose an “intermittency-friendly” energy system design. ► We compare intermittency-friendly concepts in distributed cogeneration. ► We investigate a new concept involving a heat pump and intermediate cold storage. ► We find significant improvements in operational intermittency-friendliness. ► Well-designed heat pump concepts are more cost-effective than electric boilers. -- Abstract: Distributed cogeneration has played a key role in the implementation of sustainable energy policies for three decades. However, increasing penetration levels of intermittent renewables is challenging that position. The paradigmatic case of West Denmark indicates that distributed operators are capitulating as wind power penetration levels are moving above 25%; some operators are retiring cogeneration units entirely, while other operators are making way for heat-only boilers. This development is jeopardizing the system-wide energy, economic, and environmental benefits that distributed cogeneration still has to offer. The solution is for distributed operators to adapt their technology and operational strategies to achieve a better co-existence between cogeneration and wind power. Four options for doing so are analysed including a new concept that integrates a high pressure compression heat pump using low-temperature heat recovered from flue gasses in combination with an intermediate cold storage, which enables the independent operation of heat pump and cogenerator. It is found that an electric boiler provides consistent improvements in the intermittency-friendliness of distributed cogeneration. However, well-designed heat pump concepts are more cost-effective than electric boilers, and in future markets where the gas/electricity price ratio is likely to increase, compression heat pumps in combination with intermediate thermal storages represent a superior potential for combining an intermittency-friendly pattern of operation with the efficient use of

Beyond initiation-limited translational bursting: the effects of burst size distributions on the stability of gene expression

KAUST Repository

Kuwahara, Hiroyuki

2015-11-04

A main source of gene expression noise in prokaryotes is translational bursting. It arises from efficient translation of mRNAs with low copy numbers, which makes the production of protein copies highly variable and pulsatile. To obtain analytical solutions, previous models to capture this noise source had to assume translation to be initiation-limited, representing the burst size by a specific type of a long-tail distribution. However, there is increasing evidence suggesting that the initiation is not the rate-limiting step in certain settings, for example, under stress conditions. Here, to overcome the limitations imposed by the initiation-limited assumption, we present a new analytical approach that can evaluate biological consequences of the protein burst size with a general distribution. Since our new model can capture the contribution of other factors to the translational noise, it can be used to analyze the effects of gene expression noise in more general settings. We used this new model to analytically analyze the connection between the burst size and the stability of gene expression processes in various settings. We found that the burst size with different distributions can lead to quantitatively and qualitatively different stability characteristics of protein abundance and can have non-intuitive effects. By allowing analysis of how the stability of gene expression processes changes based on various distributions of translational noise, our analytical approach is expected to enable deeper insights into the control of cell fate decision-making, the evolution of cryptic genetic variations, and fine-tuning of gene circuits.

The sample of INTEGRAL SPI-ACS gamma-ray bursts

International Nuclear Information System (INIS)

Rau, A.; Kienlin, A. von; Licht, G.G.; Hurley, K.

2005-01-01

The anti-coincidence system of the spectrometer on board INTEGRAL is operated as a nearly omni directional gamma-ray burst detector above ∼ 75 KeV. During the elapsed mission time 324 burst candidates were detected. As part of the 3rd Interplanetary Network of gamma-ray detectors the cosmic origin of 115 burst was confirmed. Here we present a preliminary analysis of the SPI-ACS gamma-ray burst sample. In particular we discuss the origin of a significant population of short events (duration < 0.2 s) and a possible method for a flux calibration of the data

Coupled hydro-neutronic calculations for fast burst reactor accidents

International Nuclear Information System (INIS)

Paternoster, R.; Kimpland, R.; Jaegers, P.; McGhee, J.

1994-01-01

Methods are described for determining the fully coupled neutronic/hydrodynamic response of fast burst reactors (FBR) under disruptive accident conditions. Two code systems, PAD (1 -D Lagrangian) and NIKE-PAGOSA (3-D Eulerian) were used to accomplish this. This is in contrast to the typical methodology that computes these responses by either single point kinetics or in a decoupled manner. This methodology is enabled by the use of modem supercomputers (CM-200). Two examples of this capability are presented: an unreflected metal fast burst assembly, and a reflected fast burst assembly typical of the Skua or SPR-III class of fast burst reactor

TRANSPORT BY INTERMITTENCY IN THE BOUNDARY OF THE DIII-D TOKAMAK

International Nuclear Information System (INIS)

BOEDO, JA; RUDAKOV, DL; MOYER, RA; MCKEE, GR; COLCHIN, RJ; SCHAFFER, MJ; STANGEBY, PG; WEST, WP; ALLEN, SL; EVANS, TE; FONCK, RJ; HOLLMANN, EM; KRASHENINNIKOV, S; LEONARD, AW; NEVINS, W; MAHDAVI, MA; PORTER, GD; TYNAN, GR; WHYTE, DG; XU, X

2002-01-01

A271 TRANSPORT BY INTERMITTENCY IN THE BOUNDARY OF THE DIII-D TOKAMAK. Intermittent plasma objectives (IPOs) featuring higher pressure than the surrounding plasma, are responsible for ∼ 50% of the E x B T radial transport in the scrape off layer (SOL) of the DIII-D tokamak in L- and H-mode discharges. Conditional averaging reveals that the IPOs are positively charged and feature internal poloidal electric fields of up to 4000 V/m. The IPOs move radially with E x B T /B 2 velocities of ∼ 2600 m/s near the last closed flux surface (LCFS), and ∼ 330 m/s near the wall. The IPOs slow down as they shrink in radial size from 4 cm at the LCFS to 0.5 cm near the wall. The skewness (i.e. asymmetry of fluctuations from the average) of probe and beam emission spectroscopy (BES) data indicate IPO formation at or near the LCFS and the existence of positive and negative IPOs which move in opposite directions. The particle content of the IPOs at the LCFS is linearly dependent on the local density and decays over ∼ 3 cm into the SOL while their temperature decays much faster (∼ 1 cm)

Recent achievements in the field of gamma-ray bursts

International Nuclear Information System (INIS)

Lu Tan; Dai Zigao

2001-01-01

Recent progresses in the field of gamma-ray bursts is briefly introduced. Gamma-ray bursts are the most energetic explosion since the Big Bang of the universe. Within a few tens of seconds, the energy released in gamma-ray bursts could be several hundred times larger than that released form the sun in its whole life (about 10 billion years). The authors will first briefly discuss the observational facts, based on which the authors will discuss the standard fireball model, the dynamical behavior and evolution of gamma-ray bursts and their afterglows. Then, various observational phenomena that contradict the standard model are given and the importance of these post-standard effects are pointed out. The questions related to the energy source of gamma-ray bursts are still unanswered, and other important questions also remain to be solved

Probing Intrinsic Properties of Short Gamma-Ray Bursts with Gravitational Waves.

Science.gov (United States)

Fan, Xilong; Messenger, Christopher; Heng, Ik Siong

2017-11-03

Progenitors of short gamma-ray bursts are thought to be neutron stars coalescing with their companion black hole or neutron star, which are one of the main gravitational wave sources. We have devised a Bayesian framework for combining gamma-ray burst and gravitational wave information that allows us to probe short gamma-ray burst luminosities. We show that combined short gamma-ray burst and gravitational wave observations not only improve progenitor distance and inclination angle estimates, they also allow the isotropic luminosities of short gamma-ray bursts to be determined without the need for host galaxy or light-curve information. We characterize our approach by simulating 1000 joint short gamma-ray burst and gravitational wave detections by Advanced LIGO and Advanced Virgo. We show that ∼90% of the simulations have uncertainties on short gamma-ray burst isotropic luminosity estimates that are within a factor of two of the ideal scenario, where the distance is known exactly. Therefore, isotropic luminosities can be confidently determined for short gamma-ray bursts observed jointly with gravitational waves detected by Advanced LIGO and Advanced Virgo. Planned enhancements to Advanced LIGO will extend its range and likely produce several joint detections of short gamma-ray bursts and gravitational waves. Third-generation gravitational wave detectors will allow for isotropic luminosity estimates for the majority of the short gamma-ray burst population within a redshift of z∼1.

Spatial-temporal variation of low-frequency earthquake bursts near Parkfield, California

Science.gov (United States)

Wu, Chunquan; Guyer, Robert; Shelly, David R.; Trugman, D.; Frank, William; Gomberg, Joan S.; Johnson, P.

2015-01-01

Tectonic tremor (TT) and low-frequency earthquakes (LFEs) have been found in the deeper crust of various tectonic environments globally in the last decade. The spatial-temporal behaviour of LFEs provides insight into deep fault zone processes. In this study, we examine recurrence times from a 12-yr catalogue of 88 LFE families with ∼730 000 LFEs in the vicinity of the Parkfield section of the San Andreas Fault (SAF) in central California. We apply an automatic burst detection algorithm to the LFE recurrence times to identify the clustering behaviour of LFEs (LFE bursts) in each family. We find that the burst behaviours in the northern and southern LFE groups differ. Generally, the northern group has longer burst duration but fewer LFEs per burst, while the southern group has shorter burst duration but more LFEs per burst. The southern group LFE bursts are generally more correlated than the northern group, suggesting more coherent deep fault slip and relatively simpler deep fault structure beneath the locked section of SAF. We also found that the 2004 Parkfield earthquake clearly increased the number of LFEs per burst and average burst duration for both the northern and the southern groups, with a relatively larger effect on the northern group. This could be due to the weakness of northern part of the fault, or the northwesterly rupture direction of the Parkfield earthquake.

Arachidonic acid triggers an oxidative burst in leukocytes

Directory of Open Access Journals (Sweden)

Pompeia C.

2003-01-01

Full Text Available The change in cellular reducing potential, most likely reflecting an oxidative burst, was investigated in arachidonic acid- (AA stimulated leukocytes. The cells studied included the human leukemia cell lines HL-60 (undifferentiated and differentiated into macrophage-like and polymorphonuclear-like cells, Jurkat and Raji, and thymocytes and macrophages from rat primary cultures. The oxidative burst was assessed by nitroblue tetrazolium reduction. AA increased the oxidative burst until an optimum AA concentration was reached and the burst decreased thereafter. In the leukemia cell lines, optimum concentration ranged from 200 to 400 µM (up to 16-fold, whereas in rat cells it varied from 10 to 20 µM. Initial rates of superoxide generation were high, decreasing steadily and ceasing about 2 h post-treatment. The continuous presence of AA was not needed to stimulate superoxide generation. It seems that the NADPH oxidase system participates in AA-stimulated superoxide production in these cells since the oxidative burst was stimulated by NADPH and inhibited by N-ethylmaleimide, diphenyleneiodonium and superoxide dismutase. Some of the effects of AA on the oxidative burst may be due to its detergent action. There apparently was no contribution of other superoxide-generating systems such as xanthine-xanthine oxidase, cytochromes P-450 and mitochondrial electron transport chain, as assessed by the use of inhibitors. Eicosanoids and nitric oxide also do not seem to interfere with the AA-stimulated oxidative burst since there was no systematic effect of cyclooxygenase, lipoxygenase or nitric oxide synthase inhibitors, but lipid peroxides may play a role, as indicated by the inhibition of nitroblue tetrazolium reduction promoted by tocopherol.

The velocities of type II solar radio bursts

International Nuclear Information System (INIS)

Tlamicha, A.; Karlicky, M.

1976-01-01

A list is presented of type II radio bursts identified at Ondrejov between January 1973 and December 1974 in the frequency range of the dynamic spectrum 70 to 810 MHz. The velocities of shock waves in the individual cases of type II bursts are given using the fourfold Newkirk model. Some problems associated with type II radio bursts and with the propagation of the shock wave into the interplanetary space and into the region of the Earth are also discussed. (author)

The LASL gamma-ray burst astronomy program

International Nuclear Information System (INIS)

Klebesadel, R.W.; Evans, W.D.; Laros, J.G.

1981-01-01

Gamma-ray burst observations performed by LASL began with the identification and initial report of the phenomenon from data acquired by the Vela satellites. The Vela instruments have recorded responses to 73 gamma-ray bursts over a ten-year interval, and are continuing to contribute toward these observations. Similar instrumentation was included aboard the NRL SOLRAD 11 spacecraft. These performed well but suffered an early demise. Recently, the LASL gamma-ray burst astronomy program has been enhanced through the implementation of experiments aboard the Pioneer Venus Orbiter and ISEF-C spacecraft. Both of these experiments are continuing to contribute data vital to trigonometric directional analyses. (orig.)

Model of chromosomal loci dynamics in bacteria as fractional diffusion with intermittent transport

Science.gov (United States)

Gherardi, Marco; Calabrese, Ludovico; Tamm, Mikhail; Cosentino Lagomarsino, Marco

2017-10-01

The short-time dynamics of bacterial chromosomal loci is a mixture of subdiffusive and active motion, in the form of rapid relocations with near-ballistic dynamics. While previous work has shown that such rapid motions are ubiquitous, we still have little grasp on their physical nature, and no positive model is available that describes them. Here, we propose a minimal theoretical model for loci movements as a fractional Brownian motion subject to a constant but intermittent driving force, and compare simulations and analytical calculations to data from high-resolution dynamic tracking in E. coli. This analysis yields the characteristic time scales for intermittency. Finally, we discuss the possible shortcomings of this model, and show that an increase in the effective local noise felt by the chromosome associates to the active relocations.

Gamma ray bursts: Current status of observations and theory

International Nuclear Information System (INIS)

Meegan, C.A.

1990-04-01

Gamma ray bursts display a wide range of temporal and spectral characteristics, but typically last several seconds and emit most of their energy in a low energy, gamma ray region. The burst sources appear to be isotropically distributed on the sky. Several lines of evidence suggest magnetic neutron stars as sources for bursts. A variety of energy sources and emission mechanisms are proposed

Infrared and X-ray bursts from the rapid burster

International Nuclear Information System (INIS)

Apparao, K.M.V.; Chitre, S.M.

1979-01-01

Studies on sudden bursts from the cosmic X-ray sources are reported. The processes occuring from the rise in luminosity of an x-ray source to its collapse are described. Records of the x-ray burst from the globular cluster NGC 6624 and the 'Rapid Burster' are shown. The Infra-red bursts from the Rapid Burster are also explained. (A.K.)

The bright optical afterglow of the nearby gamma-ray burst of 29 March 2003.

Science.gov (United States)

Price, P A; Fox, D W; Kulkarni, S R; Peterson, B A; Schmidt, B P; Soderberg, A M; Yost, S A; Berger, E; Djorgovski, S G; Frail, D A; Harrison, F A; Sari, R; Blain, A W; Chapman, S C

2003-06-19

Past studies of cosmological gamma-ray bursts (GRBs) have been hampered by their extreme distances, resulting in faint afterglows. A nearby GRB could potentially shed much light on the origin of these events, but GRBs with a redshift z burst of 29 March 2003 (GRB030329; ref. 2). The brightness of the afterglow and the prompt report of its position resulted in extensive follow-up observations at many wavelengths, along with the measurement of the redshift, z = 0.169 (ref. 4). The gamma-ray and afterglow properties of GRB030329 are similar to those of GRBs at cosmological redshifts. Observations have already identified the progenitor as a massive star that exploded as a supernova.

Prospects for rapid gamma-ray burst localization with INTEGRAL

DEFF Research Database (Denmark)

Mereghetti, S.; Jennings, D.; Pedersen, H.

1999-01-01

The SPI and IRIS instruments on INTEGRAL will detect greater than or similar to 1 GRB/month within their large fields of view. The accuracy of localization with IBIS will be a few arcminutes, hence adequate for follow-up studies at large, ground-based telescopes. We report on the current studies ...... and simulation activities aimed at designing at the ISDC an effective INTEGRAL Burst Alert System (IBAS) aisle to automatically distribute the positions of GRBs within a few tens of seconds from the event occurrence....

THE SECOND SWIFT BURST ALERT TELESCOPE GAMMA-RAY BURST CATALOG

International Nuclear Information System (INIS)

Sakamoto, T.; Baumgartner, W. H.; Cummings, J. R.; Krimm, H. A.; Barthelmy, S. D.; Gehrels, N.; Markwardt, C. B.; Parsons, A. M.; Tueller, J.; Fenimore, E. E.; Palmer, D. M.; Sato, G.; Stamatikos, M.; Ukwatta, T. N.; Zhang, B.

2011-01-01

We present the second Swift Burst Alert Telescope (BAT) catalog of gamma-ray bursts (GRBs), which contains 476 bursts detected by the BAT between 2004 December 19 and 2009 December 21. This catalog (hereafter the BAT2 catalog) presents burst trigger time, location, 90% error radius, duration, fluence, peak flux, time-averaged spectral parameters, and time-resolved spectral parameters measured by the BAT. In the correlation study of various observed parameters extracted from the BAT prompt emission data, we distinguish among long-duration GRBs (L-GRBs), short-duration GRBs (S-GRBs), and short-duration GRBs with extended emission (S-GRBs with E.E.) to investigate differences in the prompt emission properties. The fraction of L-GRBs, S-GRBs, and S-GRBs with E.E. in the catalog are 89%, 8%, and 2%, respectively. We compare the BAT prompt emission properties with the BATSE, BeppoSAX, and HETE-2 GRB samples. We also correlate the observed prompt emission properties with the redshifts for the GRBs with known redshift. The BAT T 90 and T 50 durations peak at 70 s and 30 s, respectively. We confirm that the spectra of the BAT S-GRBs are generally harder than those of the L-GRBs. The time-averaged spectra of the BAT S-GRBs with E.E. are similar to those of the L-GRBs. Whereas, the spectra of the initial short spikes of the S-GRBs with E.E. are similar to those of the S-GRBs. We show that the BAT GRB samples are significantly softer than the BATSE bright GRBs and that the time-averaged E obs peak of the BAT GRBs peaks at 80 keV, which is significantly lower energy than those of the BATSE sample, which peak at 320 keV. The time-averaged spectral properties of the BAT GRB sample are similar to those of the HETE-2 GRB samples. By time-resolved spectral analysis, we find that only 10% of the BAT observed photon indices are outside the allowed region of the synchrotron shock model. We see no obvious observed trend in the BAT T 90 and the observed spectra with redshifts. The T 90

On the Nature of the Gamma-ray Bursts

Directory of Open Access Journals (Sweden)

Kyung-Ai Hong

1987-12-01

Full Text Available Review of the γ-ray burst phenomena are presented. History of the γ-ray bursts, characteristics, and three radiation mechanisms of thermal bremsstrahlung, thermal synchrotron, and inverse Compton scattering processes are considered.

Unusual X-ray burst profiles from 4U/MXB 1636-53

Science.gov (United States)

Sztajno, M.; Truemper, J.; Pietsch, W.; Van Paradijs, J.; Stollman, G.

1985-01-01

During a one day Exosat observation eight X-ray bursts from 4U/MXB 1636-53 are observed. Four of these were very unusual. Their peak fluxes were relatively low, and they showed a distinct double peak in their bolometric flux profiles. These new double-peaked bursts are unexplained by presently available models of X-ray bursts. It is possible that the energy release in these bursts proceeds in two 'steps'. The burst profiles are not the result of an expansion and subsequent contraction of the photosphere of the neutron star. Thus, they are very different from previously observed bursts which do show a double peak in certain energy ranges but not in their bolometric flux profiles; these are satisfactorily explained in terms of photospheric radius expansion and contraction. The anticorrelation between the apparent blackbody radius and blackbody temperature is discussed in terms of the nonPlanckian character of burst spectra and it is concluded that the model calculations reported by London, Taam, and Howard in 1984 give a reasonable first-order description of the observed apparent radius changes in X-ray bursts.

Tracking Solar Type II Bursts with Space Based Radio Interferometers

Science.gov (United States)

Hegedus, Alexander M.; Kasper, Justin C.; Manchester, Ward B.

2018-06-01

The Earth’s Ionosphere limits radio measurements on its surface, blocking out any radiation below 10 MHz. Valuable insight into many astrophysical processes could be gained by having a radio interferometer in space to image the low frequency window for the first time. One application is observing type II bursts tracking solar energetic particle acceleration in Coronal Mass Ejections (CMEs). In this work we create a simulated data processing pipeline for several space based radio interferometer (SBRI) concepts and evaluate their performance in the task of localizing these type II bursts.Traditional radio astronomy software is hard coded to assume an Earth based array. To circumvent this, we manually calculate the antenna separations and insert them along with the simulated visibilities into a CASA MS file for analysis. To create the realest possible virtual input data, we take a 2-temperature MHD simulation of a CME event, superimpose realistic radio emission models from the CME-driven shock front, and propagate the signal through simulated SBRIs. We consider both probabilistic emission models derived from plasma parameters correlated with type II bursts, and analytical emission models using plasma emission wave interaction theory.One proposed SBRI is the pathfinder mission SunRISE, a 6 CubeSat interferometer to circle the Earth in a GEO graveyard orbit. We test simulated trajectories of SunRISE and image what the array recovers, comparing it to the virtual input. An interferometer on the lunar surface would be a stable alternative that avoids noise sources that affect orbiting arrays, namely the phase noise from positional uncertainty and atmospheric 10s-100s kHz noise. Using Digital Elevation Models from laser altimeter data, we test different sets of locations on the lunar surface to find near optimal configurations for tracking type II bursts far from the sun. Custom software is used to model the response of different array configurations over the lunar year

Cortical and brainstem plasticity in Tourette syndrome and obsessive-compulsive disorder.

Science.gov (United States)

Suppa, Antonio; Marsili, Luca; Di Stasio, Flavio; Berardelli, Isabella; Roselli, Valentina; Pasquini, Massimo; Cardona, Francesco; Berardelli, Alfredo

2014-10-01

Gilles de la Tourette syndrome is characterized by motor/vocal tics commonly associated with psychiatric disorders, including obsessive-compulsive disorder. We investigated primary motor cortex and brainstem plasticity in Tourette patients, exposed and unexposed to chronic drug treatment, with and without psychiatric disturbances. We also investigated primary motor cortex and brainstem plasticity in obsessive-compulsive disorder. We studied 20 Tourette patients with and without psychiatric disturbances, 15 with obsessive-compulsive disorder, and 20 healthy subjects. All groups included drug-naïve patients. We conditioned the left primary motor cortex with intermittent/continuous theta-burst stimulation and recorded motor evoked potentials. We conditioned the supraorbital nerve with facilitatory/inhibitory high-frequency stimulation and recorded the blink reflex late response area. In healthy subjects, intermittent theta-burst increased and continuous theta-burst stimulation decreased motor evoked potentials. Differently, intermittent theta-burst failed to increase and continuous theta-burst stimulation failed to decrease motor evoked potentials in Tourette patients, with and without psychiatric disturbances. In obsessive-compulsive disorder, intermittent/continuous theta-burst stimulation elicited normal responses. In healthy subjects and in subjects with obsessive-compulsive disorder, the blink reflex late response area increased after facilitatory high-frequency and decreased after inhibitory high-frequency stimulation. Conversely, in Tourette patients, with and without psychiatric disturbances, facilitatory/inhibitory high-frequency stimulation left the blink reflex late response area unchanged. Theta-burst and high-frequency stimulation elicited similar responses in drug-naïve and chronically treated patients. Tourette patients have reduced plasticity regardless of psychiatric disturbances. These findings suggest that abnormal plasticity contributes to the

DETECTING THE SUPERNOVA BREAKOUT BURST IN TERRESTRIAL NEUTRINO DETECTORS

International Nuclear Information System (INIS)

Wallace, Joshua; Burrows, Adam; Dolence, Joshua C.

2016-01-01

We calculate the distance-dependent performance of a few representative terrestrial neutrino detectors in detecting and measuring the properties of the ν e breakout burst light curve in a Galactic core-collapse supernova. The breakout burst is a signature phenomenon of core collapse and offers a probe into the stellar core through collapse and bounce. We examine cases of no neutrino oscillations and oscillations due to normal and inverted neutrino-mass hierarchies. For the normal hierarchy, other neutrino flavors emitted by the supernova overwhelm the ν e signal, making a detection of the breakout burst difficult. For the inverted hierarchy (IH), some detectors at some distances should be able to see the ν e breakout burst peak and measure its properties. For the IH, the maximum luminosity of the breakout burst can be measured at 10 kpc to accuracies of ∼30% for Hyper-Kamiokande (Hyper-K) and ∼60% for the Deep Underground Neutrino Experiment (DUNE). Super-Kamiokande (Super-K) and Jiangmen Underground Neutrino Observatory (JUNO) lack the mass needed to make an accurate measurement. For the IH, the time of the maximum luminosity of the breakout burst can be measured in Hyper-K to an accuracy of ∼3 ms at 7 kpc, in DUNE to ∼2 ms at 4 kpc, and JUNO and Super-K can measure the time of maximum luminosity to an accuracy of ∼2 ms at 1 kpc. Detector backgrounds in IceCube render a measurement of the ν e breakout burst unlikely. For the IH, a measurement of the maximum luminosity of the breakout burst could be used to differentiate between nuclear equations of state

Observation of intermittency in gene expression on cDNA microarrays

CERN Document Server

Peterson, L E

2002-01-01

We used scaled factorial moments to search for intermittency in the log expression ratios (LERs) for thousands of genes spotted on cDNA microarrays (gene chips). Results indicate varying levels of intermittency in gene expression. The observation of intermittency in the data analyzed provides a complimentary handle on moderately expressed genes, generally not tackled by conventional techniques.

Intermittent or daily montelukast versus placebo for episodic asthma in children.

Science.gov (United States)

Valovirta, Erkka; Boza, Maria L; Robertson, Colin F; Verbruggen, Nadia; Smugar, Steven S; Nelsen, Linda M; Knorr, Barbara A; Reiss, Theodore F; Philip, George; Gurner, Deborah M

2011-06-01

No standard, optimal treatment exists for severe intermittent (ie, episodic) asthma in children. However, evidence suggests that both daily and episode-driven montelukast are effective for this phenotype. To assess the regimen-related efficacy of montelukast in treating pediatric episodic asthma. A multicenter, randomized, double-blind, double-dummy, parallel-group, 52-week study was performed in children 6 months to 5 years of age comparing placebo with two regimens of montelukast 4 mg: (1) daily; or (2) episode-driven for 12 days beginning with signs/symptoms consistent with imminent cold or breathing problem. The main outcome measure was the number of asthma episodes (symptoms requiring treatment) culminating in an asthma attack (symptoms requiring physician visit, emergency room visit, corticosteroids, or hospitalization). Five hundred eighty-nine patients were randomized to daily montelukast, 591 to intermittent montelukast, and 591 to placebo. Compared with placebo, no significant difference was seen between daily montelukast (P = .510) or intermittent montelukast (P = .884) in the number of asthma episodes culminating in an asthma attack over 1 year. Daily montelukast reduced symptoms over the 12-day treatment period of asthma episodes compared with placebo (P = .045). Beta-agonist use was reduced with both daily (P = .048) and intermittent montelukast (P = .028) compared with placebo. However, because of prespecified rules for multiplicity adjustments (requiring a positive primary endpoint), statistical significance for secondary endpoints cannot be concluded. All treatments were well tolerated. Montelukast did not reduce the number of asthma episodes culminating in an asthma attack over 1 year in children 6 months to 5 years of age, although numerical improvements occurred in some endpoints. Copyright © 2011 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

Rock Burst Mechanics: Insight from Physical and Mathematical Modelling

Directory of Open Access Journals (Sweden)

J. Vacek

2008-01-01

Full Text Available Rock burst processes in mines are studied by many groups active in the field of geomechanics. Physical and mathematical modelling can be used to better understand the phenomena and mechanisms involved in the bursts. In the present paper we describe both physical and mathematical models of a rock burst occurring in a gallery of a coal mine.For rock bursts (also called bumps to occur, the rock has to possess certain particular rock burst properties leading to accumulation of energy and the potential to release this energy. Such materials may be brittle, or the rock burst may arise at the interfacial zones of two parts of the rock, which have principally different material properties (e.g. in the Poíbram uranium mines.The solution is based on experimental and mathematical modelling. These two methods have to allow the problem to be studied on the basis of three presumptions:· the solution must be time dependent,· the solution must allow the creation of cracks in the rock mass,· the solution must allow an extrusion of rock into an open space (bump effect. 

On burst-and-coast swimming performance in fish-like locomotion

International Nuclear Information System (INIS)

Chung, M-H

2009-01-01

Burst-and-coast swimming performance in fish-like locomotion is studied via two-dimensional numerical simulation. The numerical method used is the collocated finite-volume adaptive Cartesian cut-cell method developed previously. The NACA00xx airfoil shape is used as an equilibrium fish-body form. Swimming in a burst-and-coast style is computed assuming that the burst phase is composed of a single tail-beat. Swimming efficiency is evaluated in terms of the mass-specific cost of transport instead of the Froude efficiency. The effects of the Reynolds number (based on the body length and burst time), duty cycle and fineness ratio (the body length over the largest thickness) on swimming performance (momentum capacity and the mass-specific cost of transport) are studied quantitatively. The results lead to a conclusion consistent with previous findings that a larval fish seldom swims in a burst-and-coast style. Given mass and swimming speed, a fish needs the least cost if it swims in a burst-and-coast style with a fineness ratio of 8.33. This energetically optimal fineness ratio is larger than that derived from the simple hydromechanical model proposed in literature. The calculated amount of energy saving in burst-and-coast swimming is comparable with the real-fish estimation in the literature. Finally, the predicted wake-vortex structures of both continuous and burst-and-coast swimming are biologically relevant.

On burst-and-coast swimming performance in fish-like locomotion.

Science.gov (United States)

Chung, M-H

2009-09-01

Burst-and-coast swimming performance in fish-like locomotion is studied via two-dimensional numerical simulation. The numerical method used is the collocated finite-volume adaptive Cartesian cut-cell method developed previously. The NACA00xx airfoil shape is used as an equilibrium fish-body form. Swimming in a burst-and-coast style is computed assuming that the burst phase is composed of a single tail-beat. Swimming efficiency is evaluated in terms of the mass-specific cost of transport instead of the Froude efficiency. The effects of the Reynolds number (based on the body length and burst time), duty cycle and fineness ratio (the body length over the largest thickness) on swimming performance (momentum capacity and the mass-specific cost of transport) are studied quantitatively. The results lead to a conclusion consistent with previous findings that a larval fish seldom swims in a burst-and-coast style. Given mass and swimming speed, a fish needs the least cost if it swims in a burst-and-coast style with a fineness ratio of 8.33. This energetically optimal fineness ratio is larger than that derived from the simple hydromechanical model proposed in literature. The calculated amount of energy saving in burst-and-coast swimming is comparable with the real-fish estimation in the literature. Finally, the predicted wake-vortex structures of both continuous and burst-and-coast swimming are biologically relevant.

Characteristics of shock-associated fast-drift kilometric radio bursts

Science.gov (United States)

Macdowall, R. J.; Kundu, M. R.; Stone, R. G.

1987-01-01

The existence of a class of fast-drift, shock-associated (SA), kilometric radio bursts which occur at the time of metric type II emission and which are not entirely the kilometric continuation of metric type III bursts has been reported previously (Cane et al., 1981). In this paper unambiguous SA event criteria are established for the purpose of statistically comparing SA events with conventional kilometric type III bursts. Applying these criteria to all long-duration, fast-drift bursts observed by the ISEE-3 spacecraft during a 28-month interval, it is found that more than 70 percent of the events satisfying the criteria are associated with the radio signatures of coronal shocks. If a given event is associated with a metric type II or type IV burst, it is 13 times more likely to satisfy the SA criteria than an event associated only with metric type III activity.

The method of executing the vibration tendency management of the intermittent driving equipment in the nuclear plant

International Nuclear Information System (INIS)

Yonekawa, Yutaka; Fukunaga, Tatsuya

2008-01-01

The main rotary machine is often an intermittent driving machine in the nuclear plant. On the other hand, it was a problem for the vibration method to detect the vibration when rotating, and very to achieve the vibration tendency management for the equipment that did not rotate though it positively worked on the introduction of the equipment diagnosis technology by the vibration method of the rotation equipment in the nuclear plant. This time, because the tendency management system of the intermittent driving equipment is developed, and the tendency management was achieved, it introduces the outline and an actual case. (author)

Gamma-ray burst theory after Swift.

Science.gov (United States)

Piran, Tsvi; Fan, Yi-Zhong

2007-05-15

Afterglow observations in the pre-Swift era confirmed to a large extend the relativistic blast wave model for gamma-ray bursts (GRBs). Together with the observations of properties of host galaxies and the association with (type Ic) SNe, this has led to the generally accepted collapsar origin of long GRBs. However, most of the afterglow data was collected hours after the burst. The X-ray telescope and the UV/optical telescope onboard Swift are able to slew to the direction of a burst in real time and record the early broadband afterglow light curves. These observations, and in particular the X-ray observations, resulted in many surprises. While we have anticipated a smooth transition from the prompt emission to the afterglow, many observed that early light curves are drastically different. We review here how these observations are changing our understanding of GRBs.

Interaction function of coupled bursting neurons

International Nuclear Information System (INIS)

Shi Xia; Zhang Jiadong

2016-01-01

The interaction functions of electrically coupled Hindmarsh–Rose (HR) neurons for different firing patterns are investigated in this paper. By applying the phase reduction technique, the phase response curve (PRC) of the spiking neuron and burst phase response curve (BPRC) of the bursting neuron are derived. Then the interaction function of two coupled neurons can be calculated numerically according to the PRC (or BPRC) and the voltage time course of the neurons. Results show that the BPRC is more and more complicated with the increase of the spike number within a burst, and the curve of the interaction function oscillates more and more frequently with it. However, two certain things are unchanged: ϕ = 0, which corresponds to the in-phase synchronization state, is always the stable equilibrium, while the anti-phase synchronization state with ϕ = 0.5 is an unstable equilibrium. (paper)

Small-world networks exhibit pronounced intermittent synchronization

Science.gov (United States)

Choudhary, Anshul; Mitra, Chiranjit; Kohar, Vivek; Sinha, Sudeshna; Kurths, Jürgen

2017-11-01

We report the phenomenon of temporally intermittently synchronized and desynchronized dynamics in Watts-Strogatz networks of chaotic Rössler oscillators. We consider topologies for which the master stability function (MSF) predicts stable synchronized behaviour, as the rewiring probability (p) is tuned from 0 to 1. MSF essentially utilizes the largest non-zero Lyapunov exponent transversal to the synchronization manifold in making stability considerations, thereby ignoring the other Lyapunov exponents. However, for an N-node networked dynamical system, we observe that the difference in its Lyapunov spectra (corresponding to the N - 1 directions transversal to the synchronization manifold) is crucial and serves as an indicator of the presence of intermittently synchronized behaviour. In addition to the linear stability-based (MSF) analysis, we further provide global stability estimate in terms of the fraction of state-space volume shared by the intermittently synchronized state, as p is varied from 0 to 1. This fraction becomes appreciably large in the small-world regime, which is surprising, since this limit has been otherwise considered optimal for synchronized dynamics. Finally, we characterize the nature of the observed intermittency and its dominance in state-space as network rewiring probability (p) is varied.

Type III bursts in interplanetary space - Fundamental or harmonic?

Science.gov (United States)

Dulk, G. A.; Steinberg, J. L.; Hoang, S.

1984-01-01

ISEE-3 spacecraft observation of 120 relatively simple, isolated bursts in the 30-1980 kHz range are the basis of the present study of Type III bursts in the solar wind. Several characteristics are identified for many of these bursts which imply that the mode of emission changes from predominantly fundamental plasma radiation during the rise phase to predominantly second harmonic during decay. The fundamental emission begins in time coincidence with the start of Langmuir waves, confirming the conventional belief in these waves' causation of Type III bursts. Attention is given to the characteristics of fundamental components, by comparison to harmonics, at km-wavelengths.

A polarized fast radio burst at low Galactic latitude

OpenAIRE

Petroff, E.; Kasliwal, M.; Ravi, V.

2017-01-01

We report on the discovery of a new fast radio burst (FRB), FRB 150215, with the Parkes radio telescope on 2015 February 15. The burst was detected in real time with a dispersion measure (DM) of 1105.6 ± 0.8 pc cm^(−3), a pulse duration of 2.8 ^(+1.2)_(−0.5)ms, and a measured peak flux density assuming that the burst was at beam centre of 0.7 ^(+0.2)_(−0.1) Jy. The FRB originated at a Galactic longitude and latitude of 24.66°, 5.28° and 25° away from the Galactic Center. The burst was found t...

A short gamma-ray burst apparently associated with an elliptical galaxy at redshift z = 0.225.

Science.gov (United States)

Gehrels, N; Sarazin, C L; O'Brien, P T; Zhang, B; Barbier, L; Barthelmy, S D; Blustin, A; Burrows, D N; Cannizzo, J; Cummings, J R; Goad, M; Holland, S T; Hurkett, C P; Kennea, J A; Levan, A; Markwardt, C B; Mason, K O; Meszaros, P; Page, M; Palmer, D M; Rol, E; Sakamoto, T; Willingale, R; Angelini, L; Beardmore, A; Boyd, P T; Breeveld, A; Campana, S; Chester, M M; Chincarini, G; Cominsky, L R; Cusumano, G; de Pasquale, M; Fenimore, E E; Giommi, P; Gronwall, C; Grupe, D; Hill, J E; Hinshaw, D; Hjorth, J; Hullinger, D; Hurley, K C; Klose, S; Kobayashi, S; Kouveliotou, C; Krimm, H A; Mangano, V; Marshall, F E; McGowan, K; Moretti, A; Mushotzky, R F; Nakazawa, K; Norris, J P; Nousek, J A; Osborne, J P; Page, K; Parsons, A M; Patel, S; Perri, M; Poole, T; Romano, P; Roming, P W A; Rosen, S; Sato, G; Schady, P; Smale, A P; Sollerman, J; Starling, R; Still, M; Suzuki, M; Tagliaferri, G; Takahashi, T; Tashiro, M; Tueller, J; Wells, A A; White, N E; Wijers, R A M J

2005-10-06

Gamma-ray bursts (GRBs) come in two classes: long (> 2 s), soft-spectrum bursts and short, hard events. Most progress has been made on understanding the long GRBs, which are typically observed at high redshift (z approximately 1) and found in subluminous star-forming host galaxies. They are likely to be produced in core-collapse explosions of massive stars. In contrast, no short GRB had been accurately (burst GRB 050509B. Its position on the sky is near a luminous, non-star-forming elliptical galaxy at a redshift of 0.225, which is the location one would expect if the origin of this GRB is through the merger of neutron-star or black-hole binaries. The X-ray afterglow was weak and faded below the detection limit within a few hours; no optical afterglow was detected to stringent limits, explaining the past difficulty in localizing short GRBs.

Dispersion Measure Variation of Repeating Fast Radio Burst Sources

Energy Technology Data Exchange (ETDEWEB)

Yang, Yuan-Pei; Zhang, Bing, E-mail: yypspore@gmail.com, E-mail: zhang@physics.unlv.edu [Kavli Institute for Astronomy and Astrophysics, Peking University, Beijing 100871 (China)

2017-09-20

The repeating fast radio burst (FRB) 121102 was recently localized in a dwarf galaxy at a cosmological distance. The dispersion measure (DM) derived for each burst from FRB 121102 so far has not shown significant evolution, even though an apparent increase was recently seen with newly detected VLA bursts. It is expected that more repeating FRB sources may be detected in the future. In this work, we investigate a list of possible astrophysical processes that might cause DM variation of a particular FRB source. The processes include (1) cosmological scale effects such as Hubble expansion and large-scale structure fluctuations; (2) FRB local effects such as gas density fluctuation, expansion of a supernova remnant (SNR), a pulsar wind nebula, and an H ii region; and (3) the propagation effect due to plasma lensing. We find that the DM variations contributed by the large-scale structure are extremely small, and any observable DM variation is likely caused by the plasma local to the FRB source. In addition to mechanisms that decrease DM over time, we suggest that an FRB source in an expanding SNR around a nearly neutral ambient medium during the deceleration (Sedov–Taylor and snowplow) phases or in a growing H ii region can increase DM. Some effects (e.g., an FRB source moving in an H ii region or plasma lensing) can produce either positive or negative DM variations. Future observations of DM variations of FRB 121102 and other repeating FRB sources can provide important clues regarding the physical origin of these sources.

Dispersion Measure Variation of Repeating Fast Radio Burst Sources

International Nuclear Information System (INIS)

Yang, Yuan-Pei; Zhang, Bing

2017-01-01

The repeating fast radio burst (FRB) 121102 was recently localized in a dwarf galaxy at a cosmological distance. The dispersion measure (DM) derived for each burst from FRB 121102 so far has not shown significant evolution, even though an apparent increase was recently seen with newly detected VLA bursts. It is expected that more repeating FRB sources may be detected in the future. In this work, we investigate a list of possible astrophysical processes that might cause DM variation of a particular FRB source. The processes include (1) cosmological scale effects such as Hubble expansion and large-scale structure fluctuations; (2) FRB local effects such as gas density fluctuation, expansion of a supernova remnant (SNR), a pulsar wind nebula, and an H ii region; and (3) the propagation effect due to plasma lensing. We find that the DM variations contributed by the large-scale structure are extremely small, and any observable DM variation is likely caused by the plasma local to the FRB source. In addition to mechanisms that decrease DM over time, we suggest that an FRB source in an expanding SNR around a nearly neutral ambient medium during the deceleration (Sedov–Taylor and snowplow) phases or in a growing H ii region can increase DM. Some effects (e.g., an FRB source moving in an H ii region or plasma lensing) can produce either positive or negative DM variations. Future observations of DM variations of FRB 121102 and other repeating FRB sources can provide important clues regarding the physical origin of these sources.

Intermittent Testicular Torsion

African Journals Online (AJOL)

2017-06-02

Jun 2, 2017 ... had prior episodes of testicular pain, suggesting that they may have had intermittent torsion before .... None of the patients had antecedent history of sexual exposure, fever, or urinary tract infection .... torsion of the spermatic cord portends an increased risk of acute testicular infarction. J Urol 2008;180 4 ...

Phase-locking of bursting neuronal firing to dominant LFP frequency components.

Science.gov (United States)

Constantinou, Maria; Elijah, Daniel H; Squirrell, Daniel; Gigg, John; Montemurro, Marcelo A

2015-10-01

Neuronal firing in the hippocampal formation relative to the phase of local field potentials (LFP) has a key role in memory processing and spatial navigation. Firing can be in either tonic or burst mode. Although bursting neurons are common in the hippocampal formation, the characteristics of their locking to LFP phase are not completely understood. We investigated phase-locking properties of bursting neurons using simulations generated by a dual compartmental model of a pyramidal neuron adapted to match the bursting activity in the subiculum of a rat. The model was driven with stochastic input signals containing a power spectral profile consistent with physiologically relevant frequencies observed in LFP. The single spikes and spike bursts fired by the model were locked to a preferred phase of the predominant frequency band where there was a peak in the power of the driving signal. Moreover, the preferred phase of locking shifted with increasing burst size, providing evidence that LFP phase can be encoded by burst size. We also provide initial support for the model results by analysing example data of spontaneous LFP and spiking activity recorded from the subiculum of a single urethane-anaesthetised rat. Subicular neurons fired single spikes, two-spike bursts and larger bursts that locked to a preferred phase of either dominant slow oscillations or theta rhythms within the LFP, according to the model prediction. Both power-modulated phase-locking and gradual shift in the preferred phase of locking as a function of burst size suggest that neurons can use bursts to encode timing information contained in LFP phase into a spike-count code. Copyright © 2015 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.

ESA's Integral detects closest cosmic gamma-ray burst

Science.gov (United States)

2004-08-01

5 August 2004 A gamma-ray burst detected by ESA's Integral gamma-ray observatory on 3 December 2003 has been thoroughly studied for months by an armada of space and ground-based observatories. Astronomers have now concluded that this event, called GRB 031203, is the closest cosmic gamma-ray burst on record, but also the faintest. This also suggests that an entire population of sub-energetic gamma-ray bursts has so far gone unnoticed... Gamma ray burst model hi-res Size hi-res: 22 KB Credits: CXC/M. Weiss Artist impression of a low-energy gamma-ray burst This illustration describes a model for a gamma-ray burst, like the one detected by Integral on 3 December 2003 (GRB 031203). A jet of high-energy particles from a rapidly rotating black hole interacts with surrounding matter. Observations with Integral on 3 December 2003 and data on its afterglow, collected afterwards with XMM-Newton, Chandra and the Very Large Array telescope, show that GRB 031203 radiated only a fraction of the energy of normal gamma-ray bursts. Like supernovae, gamma-ray bursts are thought to be produced by the collapse of the core of a massive star. However, while the process leading to supernovae is relatively well understood, astronomers still do not know what happens when a core collapses to form a black hole. The discovery of 'under-energetic' gamma-ray bursts, like GRB 031203, should provide valuable clues as to links between supernovae, black holes and gamma-ray bursts. Lo-res JPG (22 Kb) Hi-res TIFF (5800 Kb) Cosmic gamma-ray bursts (GRBs) are flashes of gamma rays that can last from less than a second to a few minutes and occur at random positions in the sky. A large fraction of them is thought to result when a black hole is created from a dying star in a distant galaxy. Astronomers believe that a hot disc surrounding the black hole, made of gas and matter falling onto it, somehow emits an energetic beam parallel to the axis of rotation. According to the simplest picture, all GRBs

Observations of the highest energy gamma-rays from gamma-ray bursts

International Nuclear Information System (INIS)

Dingus, Brenda L.

2001-01-01

EGRET has extended the highest energy observations of gamma-ray bursts to GeV gamma rays. Such high energies imply the fireball that is radiating the gamma-rays has a bulk Lorentz factor of several hundred. However, EGRET only detected a few gamma-ray bursts. GLAST will likely detect several hundred bursts and may extend the maximum energy to a few 100 GeV. Meanwhile new ground based detectors with sensitivity to gamma-ray bursts are beginning operation, and one recently reported evidence for TeV emission from a burst

Stress Effects on Stop Bursts in Five Languages

Directory of Open Access Journals (Sweden)

Marija Tabain

2016-11-01

Full Text Available This study examines the effects of stress on the stop burst in five languages differing in number of places of articulation, as reflected in burst duration, spectral centre of gravity, and ­spectral standard deviation. The languages studied are English (three places of articulation /p t k/, the Indonesian language Makasar (four places /p t c k/, and the Central Australian languages ­Pitjantjatjara, Warlpiri (both five places /p t ʈ c k/, and Arrernte (six places /p t̪ t ʈ c k/. We find that languages differ in how they manifest stress on the consonant, with Makasar not ­showing any effect of stress at all, and Warlpiri showing an effect on burst duration, but not on the ­spectral measures. For the other languages, the velar /k/ has a “darker” quality (i.e., lower spectral centre of gravity, and/or a less diffuse spectrum (i.e., lower standard deviation under stress; while the alveolar /t/ has a “lighter” quality under stress. In addition, the dental /t̪/ has a more diffuse spectrum under stress. We suggest that this involves enhancement of the features [grave] and [diffuse] under stress, with velars being [+grave] and [–diffuse], alveolars being [–grave], and dentals being [+diffuse]. We discuss the various possible spectral effects of enhancement of these features. Finally, in the languages with five or six places of articulation, the stop burst is longer only for the palatal /c/ and the velar /k/, which have intrinsically long burst durations, and not for the anterior coronals /t̪ t ʈ/, which have intrinsically short burst durations. We suggest that in these systems, [burst duration] is a feature that separates these two groups of consonants.

Fermi/GBM Observations of SGRJ0501 + 4516 Bursts

Science.gov (United States)

Lin, Lin; Kouveliotou, Chryssa; Baring, Matthew G.; van der Horst, Alexander J.; Guiriec, Sylvain; Woods, Peter M.; Goegues, Ersin; Kaneko, Yuki; Scargle, Jeffrey; Granot, Jonathan;

Effect of Intermittent Hypercapnia on Respiratory Control in Rat Pups

Science.gov (United States)

Steggerda, Justin A.; Mayer, Catherine A.; Martin, Richard J.; Wilson, Christopher G.

2010-01-01

Preterm infants are subject to fluctuations in blood gas status associated with immature respiratory control. Intermittent hypoxia during early postnatal life has been shown to increase chemoreceptor sensitivity and destabilize the breathing pattern; however, intermittent hypercapnia remains poorly studied. Therefore, to test the hypothesis that intermittent hypercapnia results in altered respiratory control, we examined the effects of daily exposure to intermittent hypercapnia on the ventilatory response to subsequent hypercapnic and hypoxic exposure in neonatal rat pups. Exposure cycles consisted of 5 min of intermittent hypercapnia (5% CO2, 21% O2, balance N2) followed by 10 min of normoxia. Rat pups were exposed to 18 exposure cycles each day for 1 week, from postnatal day 7 to 14. We analyzed diaphragm electromyograms (EMGs) from pups exposed to subsequent acute hypercapnic (5% CO2) and hypoxic (12% O2) challenges. In response to a subsequent hypercapnia challenge, there was no significant difference in the ventilatory response between control and intermittent hypercapnia-exposed groups. In contrast, intermittent hypercapnia-exposed rat pups showed an enhanced ventilatory response to hypoxic challenge with an increase in minute EMG to 118 ± 14% of baseline versus 107 ± 13% for control pups (p < 0.05). We speculate that prior hypercapnic exposure may increase peripheral chemoreceptor response to subsequent hypoxic exposures and result in perturbed neonatal respiratory control. PMID:19752577

Polarization of a periodic solar microwave burst

Energy Technology Data Exchange (ETDEWEB)

Kaufmann, P [Universidade Mackenzie, Sao Paulo (Brazil). Centro de Radio-Astronomia e Astrofisica

1976-09-01

No fluctuations in polarization have been found during a 7 GHz solar burst showing 17s periodic pulses in intensity. Polarization effects can be produced by the propagation media in the active centre, which are not affected directly by the burst source, but situated more deeply than the observed heights at that microwave frequency.

The host galaxy of a fast radio burst.

Science.gov (United States)

Keane, E F; Johnston, S; Bhandari, S; Barr, E; Bhat, N D R; Burgay, M; Caleb, M; Flynn, C; Jameson, A; Kramer, M; Petroff, E; Possenti, A; van Straten, W; Bailes, M; Burke-Spolaor, S; Eatough, R P; Stappers, B W; Totani, T; Honma, M; Furusawa, H; Hattori, T; Morokuma, T; Niino, Y; Sugai, H; Terai, T; Tominaga, N; Yamasaki, S; Yasuda, N; Allen, R; Cooke, J; Jencson, J; Kasliwal, M M; Kaplan, D L; Tingay, S J; Williams, A; Wayth, R; Chandra, P; Perrodin, D; Berezina, M; Mickaliger, M; Bassa, C

2016-02-25

In recent years, millisecond-duration radio signals originating in distant galaxies appear to have been discovered in the so-called fast radio bursts. These signals are dispersed according to a precise physical law and this dispersion is a key observable quantity, which, in tandem with a redshift measurement, can be used for fundamental physical investigations. Every fast radio burst has a dispersion measurement, but none before now have had a redshift measurement, because of the difficulty in pinpointing their celestial coordinates. Here we report the discovery of a fast radio burst and the identification of a fading radio transient lasting ~6 days after the event, which we use to identify the host galaxy; we measure the galaxy's redshift to be z = 0.492 ± 0.008. The dispersion measure and redshift, in combination, provide a direct measurement of the cosmic density of ionized baryons in the intergalactic medium of ΩIGM = 4.9 ± 1.3 per cent, in agreement with the expectation from the Wilkinson Microwave Anisotropy Probe, and including all of the so-called 'missing baryons'. The ~6-day radio transient is largely consistent with the radio afterglow of a short γ-ray burst, and its existence and timescale do not support progenitor models such as giant pulses from pulsars, and supernovae. This contrasts with the interpretation of another recently discovered fast radio burst, suggesting that there are at least two classes of bursts.

Burst Test Qualification Analysis of DWPF Canister-Plug Weld

International Nuclear Information System (INIS)

Gupta, N.K.; Gong, Chung.

1995-02-01

The DWPF canister closure system uses resistance welding for sealing the canister nozzle and plug to ensure leak tightness. The welding group at SRTC is using the burst test to qualify this seal weld in lieu of the shear test in ASME B ampersand PV Code, Section IX, paragraph QW-196. The burst test is considered simpler and more appropriate than the shear test for this application. Although the geometry, loading and boundary conditions are quite different in the two tests, structural analyses show similarity in the failure mode of the shear test in paragraph QW-196 and the burst test on the DWPF canister nozzle Non-linear structural analyses are performed using finite element techniques to study the failure mode of the two tests. Actual test geometry and realistic stress strain data for the 304L stainless steel and the weld material are used in the analyses. The finite element models are loaded until failure strains are reached. The failure modes in both tests are shear at the failure points. Based on these observations, it is concluded that the use of a burst test in lieu of the shear test for qualifying the canister-plug weld is acceptable. The burst test analysis for the canister-plug also yields the burst pressures which compare favorably with the actual pressure found during burst tests. Thus, the analysis also provides an estimate of the safety margins in the design of these vessels

BACODINE/3rd Interplanetary Network burst localization

International Nuclear Information System (INIS)

Hurley, K.; Barthelmy, S.; Butterworth, P.; Cline, T.; Sommer, M.; Boer, M.; Niel, M.; Kouveliotou, C.; Fishman, G.; Meegan, C.

1996-01-01

Even with only two widely separated spacecraft (Ulysses and GRO), 3rd Interplanetary Network (IPN) localizations can reduce the areas of BATSE error circles by two orders of magnitude. Therefore it is useful to disseminate them as quickly as possible following BATSE bursts. We have implemented a system which transmits the light curves of BACODINE/BATSE bursts directly by e-mail to UC Berkeley immediately after detection. An automatic e-mail parser at Berkeley watches for these notices, determines the Ulysses crossing time window, and initiates a search for the burst data on the JPL computer as they are received. In ideal cases, it is possible to retrieve the Ulysses data within a few hours of a burst, generate an annulus of arrival directions, and e-mail it out to the astronomical community by local nightfall. Human operators remain in this loop, but we are developing a fully automated routine which should remove them, at least for intense events, and reduce turn-around times to an absolute minimum. We explain the current operations, the data types used, and the speed/accuracy tradeoffs

Towards an intermittency-friendly energy system

DEFF Research Database (Denmark)

Blarke, Morten

2012-01-01

Distributed cogeneration has played a key role in the implementation of sustainable energy policies for three decades. However, increasing penetration levels of intermittent renewables is challenging that position. The paradigmatic case of West Denmark indicates that distributed operators...... are capitulating as wind power penetration levels are moving above 25%; some operators are retiring cogeneration units entirely, while other operators are making way for heat-only boilers. This development is jeopardizing the system-wide energy, economic, and environmental benefits that distributed cogeneration...... still has to offer. The solution is for distributed operators to adapt their technology and operational strategies to achieve a better co-existence between cogeneration and wind power. Four options for doing so are analysed including a new concept that integrates a high pressure compression heat pump...

Intermittent Hypoxia Causes Inflammation and Injury to Human Adult Cardiac Myocytes.

Science.gov (United States)

Wu, Jing; Stefaniak, Joanna; Hafner, Christina; Schramel, Johannes Peter; Kaun, Christoph; Wojta, Johann; Ullrich, Roman; Tretter, Verena Eva; Markstaller, Klaus; Klein, Klaus Ulrich

2016-02-01

Intermittent hypoxia may occur in a number of clinical scenarios, including interruption of myocardial blood flow or breathing disorders such as obstructive sleep apnea. Although intermittent hypoxia has been linked to cardiovascular and cerebrovascular disease, the effect of intermittent hypoxia on the human heart is not fully understood. Therefore, in the present study, we compared the cellular responses of cultured human adult cardiac myocytes (HACMs) exposed to intermittent hypoxia and different conditions of continuous hypoxia and normoxia. HACMs were exposed to intermittent hypoxia (0%-21% O2), constant mild hypoxia (10% O2), constant severe hypoxia (0% O2), or constant normoxia (21% O2), using a novel cell culture bioreactor with gas-permeable membranes. Cell proliferation, lactate dehydrogenase release, vascular endothelial growth factor release, and cytokine (interleukin [IL] and macrophage migration inhibitory factor) release were assessed at baseline and after 8, 24, and 72 hours of exposure. A signal transduction pathway finder array was performed to determine the changes in gene expression. In comparison with constant normoxia and constant mild hypoxia, intermittent hypoxia induced earlier and greater inflammatory response and extent of cell injury as evidenced by lower cell numbers and higher lactate dehydrogenase, vascular endothelial growth factor, and proinflammatory cytokine (IL-1β, IL-6, IL-8, and macrophage migration inhibitory factor) release. Constant severe hypoxia showed more detrimental effects on HACMs at later time points. Pathway analysis demonstrated that intermittent hypoxia primarily altered gene expression in oxidative stress, Wnt, Notch, and hypoxia pathways. Intermittent and constant severe hypoxia, but not constant mild hypoxia or normoxia, induced inflammation and cell injury in HACMs. Cell injury occurred earliest and was greatest after intermittent hypoxia exposure. Our in vitro findings suggest that intermittent hypoxia

Intermittent, Non Cyclic Severe Mechanical Aortic Valve Regurgitation

Science.gov (United States)

Choi, Jong Hyun; Song, Seunghwan; Lee, Myung-Yong

2013-01-01

Mechanical aortic prosthesis dysfunction can result from thrombosis or pannus formation. We describe an unusual case of intermittent, non cyclic mechanical aortic prosthesis dysfunction due to pannus formation with thrombus in the absence of systolic restriction of disk excursion, that presented with intermittent severe aortic regurgitation. PMID:24459568

Degrees-of-Freedom of the MIMO Three-Way Channel with Node-Intermittency

KAUST Repository

Neu, Joachim

2017-08-28

The characterization of fundamental performance bounds of many-to-many communication systems in which participating nodes are active in an intermittent way is one of the major challenges in communication theory. In order to address this issue, we introduce the multiple-input multiple-output (MIMO) three-way channel (3WC) with an intermittent node and study its degrees-of-freedom (DoF) region and sum-DoF. We devise a non-adaptive encoding scheme based on zero-forcing, interference alignment and erasure coding, and show its DoF region (and thus sum-DoF) optimality for non-intermittent 3WCs and its sum-DoF optimality for (node-)intermittent 3WCs. However, we show by example that in general some DoF tuples in the intermittent 3WC can only be achieved by adaptive schemes, such as multi-hop or decode-forward relaying. This shows that non-adaptive encoding is sufficient for the non-intermittent 3WC and for the sum-DoF of intermittent 3WCs, but adaptive encoding is necessary for the DoF region of intermittent 3WCs. Our work contributes to a better understanding of the fundamental limits of multi-way communication systems with intermittency and the impact of adaptation therein.

Glutamate-induced glutamate release: A proposed mechanism for calcium bursting in astrocytes

Science.gov (United States)

Larter, Raima; Craig, Melissa Glendening

2005-12-01

Here we present a new model for the generation of complex calcium-bursting patterns in astrocytes, a type of brain cell recently implicated in a variety of neural functions including memory formation. The model involves two positive feedback processes, in which the key feedback species are calcium ion and glutamate. The latter is the most abundant excitatory neurotransmitter in the brain and has been shown to be involved in bidirectional communication between astrocytes and nearby neurons. The glutamate feedback process considered here is shown to be critical for the generation of complex bursting oscillations in the astrocytes and to, perhaps, code for information which may be passed from neuron to neuron via the astrocyte. These processes may be involved in memory storage and formation as well as in mechanisms which lead to dynamical diseases such as epilepsy.

Gamma-ray bursts from black hole accretion disks

International Nuclear Information System (INIS)

Strong, I.B.

1975-01-01

The suggestion was first made more than a year ago that gamma-ray bursts might originate in the neighborhood of black holes, based on some rather circumstantial evidence linking Cygnus X-1, the prime black-hole candidate, with two of the then-known gamma-ray bursts. Since then additional evidence makes the idea still more plausible. The evidence is summarized briefly, a physical model for production of gamma-ray bursts is given, and several of the more interesting consequences of such an origin are pointed out. (orig.) [de

Gamma-ray bursts

CERN Document Server

Wijers, Ralph A M J; Woosley, Stan

2012-01-01

Cosmic gamma ray bursts (GRBs) have fascinated scientists and the public alike since their discovery in the late 1960s. Their story is told here by some of the scientists who participated in their discovery and, after many decades of false starts, solved the problem of their origin. Fourteen chapters by active researchers in the field present a detailed history of the discovery, a comprehensive theoretical description of GRB central engine and emission models, a discussion of GRB host galaxies and a guide to how GRBs can be used as cosmological tools. Observations are grouped into three sets from the satellites CGRO, BeppoSAX and Swift, and followed by a discussion of multi-wavelength observations. This is the first edited volume on GRB astrophysics that presents a fully comprehensive review of the subject. Utilizing the latest research, Gamma-ray Bursts is an essential desktop companion for graduate students and researchers in astrophysics.

Intermittent fasting: a "new" historical strategy for controlling seizures?

Science.gov (United States)

Hartman, Adam L; Rubenstein, James E; Kossoff, Eric H

2013-05-01

In antiquity, fasting was a treatment for epilepsy and a rationale for the ketogenic diet (KD). Preclinical data indicate the KD and intermittent fasting do not share identical anticonvulsant mechanisms. We implemented an intermittent fasting regimen in six children with an incomplete response to a KD. Three patients adhered to the combined intermittent fasting/KD regimen for 2 months and four had transient improvement in seizure control, albeit with some hunger-related adverse reactions. Copyright © 2012 Elsevier B.V. All rights reserved.

V/V(max) test applied to SMM gamma-ray bursts

Science.gov (United States)

Matz, S. M.; Higdon, J. C.; Share, G. H.; Messina, D. C.; Iadicicco, A.

1992-01-01

We have applied the V/V(max) test to candidate gamma-ray bursts detected by the Gamma-Ray Spectrometer (GRS) aboard the SMM satellite to examine quantitatively the uniformity of the burst source population. For a sample of 132 candidate bursts identified in the GRS data by an automated search using a single uniform trigger criterion we find average V/V(max) = 0.40 +/- 0.025. This value is significantly different from 0.5, the average for a uniform distribution in space of the parent population of burst sources; however, the shape of the observed distribution of V/V(max) is unusual and our result conflicts with previous measurements. For these reasons we can currently draw no firm conclusion about the distribution of burst sources.

THORACOLUMBAR BURST FRACTURE: STRUCTURAL CHANGES AND CLINICAL OUTCOME OF TREATMENT

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Rodrigo Arnold Tisot

2016-03-01

Full Text Available ABSTRACT Objective: To evaluate the correlation between structural changes in burst fractures of thoracic and lumbar spine with clinical outcome of the treatment. Methods: A retrospective study in 25 patients with fractures of thoracic and lumbar spine burst fractures without neurological deficit. Eleven patients underwent conservative treatment and for the remaining the treatment was surgical. All patients were followed up for at least 24 months. The cases were evaluated by a protocol that included: posttraumatic measurement of kyphosis, vertebral body collapse and narrowing of the spinal canal, the visual analog scale of pain, and the quality of life questionnaire SF-36 at the follow-up. For statistical analysis, the significance level was 5% and the software SPSS 18.0 was used. Results: No statistically significant difference was observed when comparing the clinical outcomes of one treatment over another. Similarly, there was no statistically significant correlation between kyphosis and post-traumatic narrowing of the spinal canal with clinical worsening in the follow-up, regardless of the treatment used. We found a positive correlation (p<0.05 between initial collapse and SF-36 domains in both groups (operated and non-operated. Conclusion: There was no significant superiority of one treatment over the other, and no correlation was found between kyphosis and spinal canal narrowing in burst fractures of the thoracic and lumbar spine without neurological deficit. However, there was correlation between initial collapse and clinical outcome in some domains of the SF-36 questionnaire.

Ablation of silicon with bursts of femtosecond laser pulses

Science.gov (United States)

Gaudiuso, Caterina; Kämmer, Helena; Dreisow, Felix; Ancona, Antonio; Tünnermann, Andreas; Nolte, Stefan

2016-03-01

We report on an experimental investigation of ultrafast laser ablation of silicon with bursts of pulses. The pristine 1030nm-wavelength 200-fs pulses were split into bursts of up to 16 sub-pulses with time separation ranging from 0.5ps to 4080ps. The total ablation threshold fluence was measured depending on the burst features, finding that it strongly increases with the number of sub-pulses for longer sub-pulse delays, while a slowly increasing trend is observed for shorter separation time. The ablation depth per burst follows two different trends according to the time separation between the sub-pulses, as well as the total threshold fluence. For delays shorter than 4ps it decreases with the number of pulses, while for time separations longer than 510ps, deeper craters were achieved by increasing the number of subpulses in the burst, probably due to a change of the effective penetration depth.

Closing in on a Short-Hard Burst Progenitor: Constraints From Early-Time Optical Imaging and Spectroscopy of a Possible Host Galaxy of GRB 050509b

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