THE SMALL-SCALE PHYSICAL STRUCTURE AND FRAGMENTATION DIFFERENCE OF TWO EMBEDDED INTERMEDIATE-MASS PROTOSTARS IN ORION

Energy Technology Data Exchange (ETDEWEB)

Van Kempen, T. A. [Joint ALMA Offices, Alonso de Cordova 3107, Vitacura, Santiago (Chile); Longmore, S. N. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Johnstone, D. [National Research Council Canada, Herzberg Institute for Astronomy, 5071 West Saanich Road, Victoria, BC (Canada); Pillai, T. [Caltech, MC 249-17, 1200 East California Blvd, Pasadena, CA 91125 (United States); Fuente, A., E-mail: tkempen@alma.cl [Observatorio Astronomico Nacional (OAN), Apdo. 112, E-28803 Alcala de Henares, Madrid (Spain)

2012-06-01

Intermediate-mass (IM) protostars, the bridge between the very common solar-like protostars and the more massive, but rarer, O and B stars, can only be studied at high physical spatial resolutions in a handful of clouds. In this paper, we present and analyze the continuum results from an observing campaign at the Submillimeter Array (SMA) targeting two well-studied IM protostars in Orion, NGC 2071 and L1641 S3 MMS 1. The extended SMA (eSMA) probes structure at angular resolutions up to 0.''2, revealing protostellar disks on scales of {approx}200 AU. Continuum flux measurements on these scales indicate that a significant amount of mass, a few tens of M{sub Sun }, is present. Envelope, stellar, and disk masses are derived using compact, extended, and eSMA configurations and compared against spectral energy distribution fitting models. We hypothesize that fragmentation into three components occurred within NGC 2071 at an early time, when the envelopes were less than 10% of their current masses, e.g., <0.5 M{sub Sun }. No fragmentation occurred for L1641 S3 MMS 1. For NGC 2071, evidence is given that the bulk of the envelope material currently around each source was accreted after the initial fragmentation. In addition, about 30% of the total core mass is not yet associated to one of the three sources. A global accretion model is favored and a potential accretion history of NGC 2071 is presented. It is shown that the relatively low level of fragmentation in NGC 2071 was stifled compared to the expected fragmentation from a Jeans argument. Similarly, the lack of fragmentation in L1641 S3 MMS 1 is likely due to similar arguments.

Three ancient halo subgiants: precise parallaxes, compositions, ages, and implications for globular clusters , ,

Energy Technology Data Exchange (ETDEWEB)

VandenBerg, Don A. [Department of Physics and Astronomy, University of Victoria, P.O. Box 1700 STN CSC, Victoria, B.C., V8W 2Y2 (Canada); Bond, Howard E. [Department of Astronomy and Astrophysics, Pennsylvania State University, University Park, PA 16802 (United States); Nelan, Edmund P. [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Nissen, P. E. [Stellar Astrophysics Centre, Department of Physics and Astronomy, Aarhus University, Ny Munkegade 120, DK-8000 Aarhus C (Denmark); Schaefer, Gail H. [The CHARA Array of Georgia State University, Mount Wilson Observatory, Mount Wilson, CA 91023 (United States); Harmer, Dianne, E-mail: vandenbe@uvic.ca, E-mail: heb11@psu.edu, E-mail: nelan@stsci.edu, E-mail: pen@phys.au.dk, E-mail: schaefer@chara-array.org, E-mail: diharmer@noao.edu [National Optical Astronomy Observatories, 950 North Cherry Avenue, Tucson, AZ 85726 (United States)

2014-09-10

The most accurate ages for the oldest stars are those obtained for nearby halo subgiants because they depend almost entirely on just the measured parallaxes and absolute oxygen abundances. In this study, we have used the Fine Guidance Sensors on the Hubble Space Telescope to determine trigonometric parallaxes, with precisions of 2.1% or better, for the Population II subgiants HD 84937, HD 132475, and HD 140283. High quality spectra have been used to derive their surface abundances of O, Fe, Mg, Si, and Ca, which are assumed to be 0.1-0.15 dex less than their initial abundances due to the effects of diffusion. Comparisons of isochrones with the three subgiants on the (log T {sub eff}, M{sub V} ) diagram yielded ages of 12.08 ± 0.14, 12.56 ± 0.46, and 14.27 ± 0.38 Gyr for HD 84937, HD 132475, and HD 140283, in turn, where each error bar includes only the parallax uncertainty. The total uncertainty is estimated to be ∼ ± 0.8 Gyr (larger in the case of the near-turnoff star HD 84937). Although the age of HD 140283 is greater than the age of the universe as inferred from the cosmic microwave background by ∼0.4-0.5 Gyr, this discrepancy is at a level of <1σ. Nevertheless, the first Population II stars apparently formed very soon after the Big Bang. (Stellar models that neglect diffusive processes seem to be ruled out as they would predict that HD 140283 is ∼1.5 Gyr older than the universe.) The field halo subgiants appear to be older than globular clusters of similar metallicities: if distances close to those implied by the RR Lyrae standard candle are assumed, M 92 and M 5 are younger than HD 140283 and HD 132475 by ∼1.5 and ∼1.0 Gyr, respectively.

LC-IMS-MS Feature Finder: detecting multidimensional liquid chromatography, ion mobility and mass spectrometry features in complex datasets.

Science.gov (United States)

Crowell, Kevin L; Slysz, Gordon W; Baker, Erin S; LaMarche, Brian L; Monroe, Matthew E; Ibrahim, Yehia M; Payne, Samuel H; Anderson, Gordon A; Smith, Richard D

2013-11-01

The addition of ion mobility spectrometry to liquid chromatography-mass spectrometry experiments requires new, or updated, software tools to facilitate data processing. We introduce a command line software application LC-IMS-MS Feature Finder that searches for molecular ion signatures in multidimensional liquid chromatography-ion mobility spectrometry-mass spectrometry (LC-IMS-MS) data by clustering deisotoped peaks with similar monoisotopic mass, charge state, LC elution time and ion mobility drift time values. The software application includes an algorithm for detecting and quantifying co-eluting chemical species, including species that exist in multiple conformations that may have been separated in the IMS dimension. LC-IMS-MS Feature Finder is available as a command-line tool for download at http://omics.pnl.gov/software/LC-IMS-MS_Feature_Finder.php. The Microsoft.NET Framework 4.0 is required to run the software. All other dependencies are included with the software package. Usage of this software is limited to non-profit research to use (see README). rds@pnnl.gov. Supplementary data are available at Bioinformatics online.

Production of intermediate-mass dileptons in relativistic heavy ion collisions

International Nuclear Information System (INIS)

Kvasnikova, Ioulia; Gale, Charles; Kumar Srivastava, Dinesh

2002-01-01

The production of intermediate-mass dileptons in ultrarelativistic nuclear collisions at SPS energies is studied. The acceptance and detector resolution inherent to measurements by the NA50 experimental collaboration are accurately modeled. The measured centrality dependence of the intermediate mass lepton pair excess is also addressed

Ion Mobility Spectrometer / Mass Spectrometer (IMS-MS)

Energy Technology Data Exchange (ETDEWEB)

Hunka, Deborah E. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Austin, Daniel [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2005-10-01

The use of Ion Mobility Spectrometry (IMS)in the Detection of Contraband Sandia researchers use ion mobility spectrometers for trace chemical detection and analysis in a variety of projects and applications. Products developed in recent years based on IMS-technology include explosives detection personnel portals, the Material Area Access (MAA) checkpoint of the future, an explosives detection vehicle portal, hand-held detection systems such as the Hound and Hound II (all 6400), micro-IMS sensors (1700), ordnance detection (2500), and Fourier Transform IMS technology (8700). The emphasis to date has been on explosives detection, but the detection of chemical agents has also been pursued (8100 and 6400).

Ion mobility spectrometry-mass spectrometry (IMS-MS) for on- and offline analysis of atmospheric gas and aerosol species

Science.gov (United States)

Krechmer, Jordan E.; Groessl, Michael; Zhang, Xuan; Junninen, Heikki; Massoli, Paola; Lambe, Andrew T.; Kimmel, Joel R.; Cubison, Michael J.; Graf, Stephan; Lin, Ying-Hsuan; Budisulistiorini, Sri H.; Zhang, Haofei; Surratt, Jason D.; Knochenmuss, Richard; Jayne, John T.; Worsnop, Douglas R.; Jimenez, Jose-Luis; Canagaratna, Manjula R.

2016-07-01

Measurement techniques that provide molecular-level information are needed to elucidate the multiphase processes that produce secondary organic aerosol (SOA) species in the atmosphere. Here we demonstrate the application of ion mobility spectrometry-mass spectrometry (IMS-MS) to the simultaneous characterization of the elemental composition and molecular structures of organic species in the gas and particulate phases. Molecular ions of gas-phase organic species are measured online with IMS-MS after ionization with a custom-built nitrate chemical ionization (CI) source. This CI-IMS-MS technique is used to obtain time-resolved measurements (5 min) of highly oxidized organic molecules during the 2013 Southern Oxidant and Aerosol Study (SOAS) ambient field campaign in the forested SE US. The ambient IMS-MS signals are consistent with laboratory IMS-MS spectra obtained from single-component carboxylic acids and multicomponent mixtures of isoprene and monoterpene oxidation products. Mass-mobility correlations in the 2-D IMS-MS space provide a means of identifying ions with similar molecular structures within complex mass spectra and are used to separate and identify monoterpene oxidation products in the ambient data that are produced from different chemical pathways. Water-soluble organic carbon (WSOC) constituents of fine aerosol particles that are not resolvable with standard analytical separation methods, such as liquid chromatography (LC), are shown to be separable with IMS-MS coupled to an electrospray ionization (ESI) source. The capability to use ion mobility to differentiate between isomers is demonstrated for organosulfates derived from the reactive uptake of isomers of isoprene epoxydiols (IEPOX) onto wet acidic sulfate aerosol. Controlled fragmentation of precursor ions by collisionally induced dissociation (CID) in the transfer region between the IMS and the MS is used to validate MS peak assignments, elucidate structures of oligomers, and confirm the

Testing asteroseismic radii of dwarfs and subgiants with Kepler and Gaia

Science.gov (United States)

Sahlholdt, C. L.; Silva Aguirre, V.; Casagrande, L.; Mosumgaard, J. R.; Bojsen-Hansen, M.

2018-05-01

We test asteroseismic radii of Kepler main-sequence and subgiant stars by deriving their parallaxes which are compared with those of the first Gaia data release. We compute radii based on the asteroseismic scaling relations as well as by fitting observed oscillation frequencies to stellar models for a subset of the sample, and test the impact of using effective temperatures from either spectroscopy or the infrared flux method. An offset of 3 per cent, showing no dependency on any stellar parameters, is found between seismic parallaxes derived from frequency modelling and those from Gaia. For parallaxes based on radii from the scaling relations, a smaller offset is found on average; however, the offset becomes temperature dependent which we interpret as problems with the scaling relations at high stellar temperatures. Using the hotter infrared flux method temperature scale, there is no indication that radii from the scaling relations are inaccurate by more than about 5 per cent. Taking the radii and masses from the modelling of individual frequencies as reference values, we seek to correct the scaling relations for the observed temperature trend. This analysis indicates that the scaling relations systematically overestimate radii and masses at high temperatures, and that they are accurate to within 5 per cent in radius and 13 per cent in mass for main-sequence stars with temperatures below 6400 K. However, further analysis is required to test the validity of the corrections on a star-by-star basis and for more evolved stars.

Restrictions on the masses and coupling constants of excited intermediate bosons

International Nuclear Information System (INIS)

Kaidalov, A.B.; Nogteva, A.V.

1985-01-01

The properties of the intermediate bosons are discussed in the framework of composite models which include not only the W +- and Z 0 bosons but also their excited states with large masses. The influence of the excited states on the values of the masses of the W +- and Z 0 bosons is investigated. Restrictions on the masses and coupling constants of the excited intermediate bosons are obtained

Low-energy consequences of superstring-inspired models with intermediate-mass scales

International Nuclear Information System (INIS)

Gabbiani, F.

1987-01-01

The phenomenological consequences of implementing intermediate-mass scales in E 6 superstring-inspired models are discussed. Starting from a suitable Calabi-Yau compactification with b 1,1 >1, one gets, after Hosotani breaking, the rank r=5 gauge group SU(3) C x SU(2) L x U(1) Y x U(1) E , that is broken at an intermediate-mass scale down to the standard-model group. The analysis of both the intermediate and the electroweak breaking is performed in the two cases Λ c = M x and Λ c x , where Λ c is the scale at which the hidden sector gauginos condensate. It is performed quantitatively the minimization of the low-energy effective potential and the renormalization group analysis, yielding a viable set of mass spectra and confirming the reliability of the intermediate-breaking scheme

Three Ancient Halo Subgiants: Precise Parallaxes, Compositions, Ages, and Implications for Globular Clusters

DEFF Research Database (Denmark)

VandenBerg, Don A.; Bond, Howard E.; Nelan, Edmund P.

2014-01-01

very soon after the Big Bang. (Stellar models that neglect diffusive processes seem to be ruled out as they would predict that HD 140283 is ~1.5 Gyr older than the universe.) The field halo subgiants appear to be older than globular clusters of similar metallicities: if distances close to those implied...

MALDI (matrix assisted laser desorption ionization) Imaging Mass Spectrometry (IMS) of skin: Aspects of sample preparation.

Science.gov (United States)

de Macedo, Cristiana Santos; Anderson, David M; Schey, Kevin L

2017-11-01

MALDI (matrix assisted laser desorption ionization) Imaging Mass Spectrometry (IMS) allows molecular analysis of biological materials making possible the identification and localization of molecules in tissues, and has been applied to address many questions on skin pathophysiology, as well as on studies about drug absorption and metabolism. Sample preparation for MALDI IMS is the most important part of the workflow, comprising specimen collection and preservation, tissue embedding, cryosectioning, washing, and matrix application. These steps must be carefully optimized for specific analytes of interest (lipids, proteins, drugs, etc.), representing a challenge for skin analysis. In this review, critical parameters for MALDI IMS sample preparation of skin samples will be described. In addition, specific applications of MALDI IMS of skin samples will be presented including wound healing, neoplasia, and infection. Copyright © 2017 Elsevier B.V. All rights reserved.

Chemical evolution of the Galactic bulge as traced by microlensed dwarf and subgiant stars. Detailed abundance analysis of OGLE-2008-BLG-209S

OpenAIRE

Bensby, T.; Johnson, J. A.; Cohen, J.; Feltzing, S.; Udalski, A.; Gould, A.; Huang, W.; Thompson, I.; Simmerer, J.; Adén, D.

2009-01-01

AIMS. Our aims are twofold. First we aim to evaluate the robustness and accuracy of stellar parameters and detailed elemental abundances that can be derived from high-resolution spectroscopic observations of microlensed dwarf and subgiant stars. We then aim to use microlensed dwarf and subgiant stars to investigate the abundance structure and chemical evolution of the Milky Way Bulge. [ABRIDGED] METHODS. We present a detailed elemental abundance analysis of OGLE-2008-BLG-209S, the source star...

The masses of retired A stars with asteroseismology

DEFF Research Database (Denmark)

North, Thomas S. H.; Campante, Tiago L.; Miglio, Andrea

2017-01-01

We investigate the masses of 'retired A stars' using asteroseismic detections on seven low-luminosity red-giant and sub-giant stars observed by the NASA Kepler and K2 missions. Our aim is to explore whether masses derived from spectroscopy and isochrone fitting may have been systematically overes...

MALDI FTICR IMS of Intact Proteins: Using Mass Accuracy to Link Protein Images with Proteomics Data

Science.gov (United States)

Spraggins, Jeffrey M.; Rizzo, David G.; Moore, Jessica L.; Rose, Kristie L.; Hammer, Neal D.; Skaar, Eric P.; Caprioli, Richard M.

2015-06-01

MALDI imaging mass spectrometry is a highly sensitive and selective tool used to visualize biomolecules in tissue. However, identification of detected proteins remains a difficult task. Indirect identification strategies have been limited by insufficient mass accuracy to confidently link ion images to proteomics data. Here, we demonstrate the capabilities of MALDI FTICR MS for imaging intact proteins. MALDI FTICR IMS provides an unprecedented combination of mass resolving power (~75,000 at m/z 5000) and accuracy (differentiate a series of oxidation products of S100A8 ( m/z 10,164.03, -2.1ppm), a subunit of the heterodimer calprotectin, in kidney tissue from mice infected with Staphylococcus aureus. S100A8 - M37O/C42O3 ( m/z 10228.00, -2.6ppm) was found to co-localize with bacterial microcolonies at the center of infectious foci. The ability of MALDI FTICR IMS to distinguish S100A8 modifications is critical to understanding calprotectin's roll in nutritional immunity.

Seismic constraints on the radial dependence of the internal rotation profiles of six Kepler subgiants and young red giants

Science.gov (United States)

Deheuvels, S.; Doğan, G.; Goupil, M. J.; Appourchaux, T.; Benomar, O.; Bruntt, H.; Campante, T. L.; Casagrande, L.; Ceillier, T.; Davies, G. R.; De Cat, P.; Fu, J. N.; García, R. A.; Lobel, A.; Mosser, B.; Reese, D. R.; Regulo, C.; Schou, J.; Stahn, T.; Thygesen, A. O.; Yang, X. H.; Chaplin, W. J.; Christensen-Dalsgaard, J.; Eggenberger, P.; Gizon, L.; Mathis, S.; Molenda-Żakowicz, J.; Pinsonneault, M.

2014-04-01

Context. We still do not understand which physical mechanisms are responsible for the transport of angular momentum inside stars. The recent detection of mixed modes that contain the clear signature of rotation in the spectra of Kepler subgiants and red giants gives us the opportunity to make progress on this question. Aims: Our aim is to probe the radial dependence of the rotation profiles for a sample of Kepler targets. For this purpose, subgiants and early red giants are particularly interesting targets because their rotational splittings are more sensitive to the rotation outside the deeper core than is the case for their more evolved counterparts. Methods: We first extracted the rotational splittings and frequencies of the modes for six young Kepler red giants. We then performed a seismic modeling of these stars using the evolutionary codes Cesam2k and astec. By using the observed splittings and the rotational kernels of the optimal models, we inverted the internal rotation profiles of the six stars. Results: We obtain estimates of the core rotation rates for these stars, and upper limits to the rotation in their convective envelope. We show that the rotation contrast between the core and the envelope increases during the subgiant branch. Our results also suggest that the core of subgiants spins up with time, while their envelope spins down. For two of the stars, we show that a discontinuous rotation profile with a deep discontinuity reproduces the observed splittings significantly better than a smooth rotation profile. Interestingly, the depths that are found to be most probable for the discontinuities roughly coincide with the location of the H-burning shell, which separates the layers that contract from those that expand. Conclusions: We characterized the differential rotation pattern of six young giants with a range of metallicities, and with both radiative and convective cores on the main sequence. This will bring observational constraints to the

Spatially resolved chemical analysis of cicada wings using laser-ablation electrospray ionization (LAESI) imaging mass spectrometry (IMS).

Science.gov (United States)

Román, Jessica K; Walsh, Callee M; Oh, Junho; Dana, Catherine E; Hong, Sungmin; Jo, Kyoo D; Alleyne, Marianne; Miljkovic, Nenad; Cropek, Donald M

2018-03-01

Laser-ablation electrospray ionization (LAESI) imaging mass spectrometry (IMS) is an emerging bioanalytical tool for direct imaging and analysis of biological tissues. Performing ionization in an ambient environment, this technique requires little sample preparation and no additional matrix, and can be performed on natural, uneven surfaces. When combined with optical microscopy, the investigation of biological samples by LAESI allows for spatially resolved compositional analysis. We demonstrate here the applicability of LAESI-IMS for the chemical analysis of thin, desiccated biological samples, specifically Neotibicen pruinosus cicada wings. Positive-ion LAESI-IMS accurate ion-map data was acquired from several wing cells and superimposed onto optical images allowing for compositional comparisons across areas of the wing. Various putative chemical identifications were made indicating the presence of hydrocarbons, lipids/esters, amines/amides, and sulfonated/phosphorylated compounds. With the spatial resolution capability, surprising chemical distribution patterns were observed across the cicada wing, which may assist in correlating trends in surface properties with chemical distribution. Observed ions were either (1) equally dispersed across the wing, (2) more concentrated closer to the body of the insect (proximal end), or (3) more concentrated toward the tip of the wing (distal end). These findings demonstrate LAESI-IMS as a tool for the acquisition of spatially resolved chemical information from fragile, dried insect wings. This LAESI-IMS technique has important implications for the study of functional biomaterials, where understanding the correlation between chemical composition, physical structure, and biological function is critical. Graphical abstract Positive-ion laser-ablation electrospray ionization mass spectrometry coupled with optical imaging provides a powerful tool for the spatially resolved chemical analysis of cicada wings.

An intermediate-mass black hole in the centre of the globular cluster 47 Tucanae.

Science.gov (United States)

Kızıltan, Bülent; Baumgardt, Holger; Loeb, Abraham

2017-02-08

Intermediate-mass black holes should help us to understand the evolutionary connection between stellar-mass and super-massive black holes. However, the existence of intermediate-mass black holes is still uncertain, and their formation process is therefore unknown. It has long been suspected that black holes with masses 100 to 10,000 times that of the Sun should form and reside in dense stellar systems. Therefore, dedicated observational campaigns have targeted globular clusters for many decades, searching for signatures of these elusive objects. All candidate signatures appear radio-dim and do not have the X-ray to radio flux ratios required for accreting black holes. Based on the lack of an electromagnetic counterpart, upper limits of 2,060 and 470 solar masses have been placed on the mass of a putative black hole in 47 Tucanae (NGC 104) from radio and X-ray observations, respectively. Here we show there is evidence for a central black hole in 47 Tucanae with a mass of solar masses when the dynamical state of the globular cluster is probed with pulsars. The existence of an intermediate-mass black hole in the centre of one of the densest clusters with no detectable electromagnetic counterpart suggests that the black hole is not accreting at a sufficient rate to make it electromagnetically bright and therefore, contrary to expectations, is gas-starved. This intermediate-mass black hole might be a member of an electromagnetically invisible population of black holes that grow into supermassive black holes in galaxies.

Gemini Spectroscopic Survey of Young Intermediate-Mass Star-Forming Regions

Science.gov (United States)

Lundquist, Michael; Kobulnicky, Henry

2018-01-01

The majority of stars form in embedded clusters. Current research into star formation has focused on either high-mass star-forming regions or low-mass star-forming regions. We present the results from a Gemini spectroscopic survey of young intermediate-mass star-forming regions. These are star forming regions selected to produce stars up to but not exceeding 8 solar masses. We obtained spectra of these regions with GNIRS on Gemini North and Flamingos-2 on Gemini South. We also combine this with near-infrared imaging from 2MASS, UKIDSS, and VVV to study the stellar content.

Imaging mass spectrometry tackles interfacial challenges in electrochemistry

Energy Technology Data Exchange (ETDEWEB)

Yu, Xiao-Ying

2017-12-01

Electrochemistry has played a significant role in many research fields. Owing to its sensitivity and selectivity, in situ electroanalysis has been widely used as a fast and economical means for achieving outstanding results. Although many spectroscopic techniques have been used in electrochemistry, the challenges to capture short-lived intermediate species as a result of electron transfer in the buried solid electrode and electrolyte solution interface remains a grand challenge. In situ imaging mass spectrometry (IMS) recently has been extended to capture transient species in electrochemistry. This review intends to summarize newest development of IMS and its applications in advancing fundamental electrochemistry.

Measuring Intermediate-Mass Black-Hole Binaries with Advanced Gravitational Wave Detectors.

Science.gov (United States)

Veitch, John; Pürrer, Michael; Mandel, Ilya

2015-10-02

We perform a systematic study to explore the accuracy with which the parameters of intermediate-mass black-hole binary systems can be measured from their gravitational wave (GW) signatures using second-generation GW detectors. We make use of the most recent reduced-order models containing inspiral, merger, and ringdown signals of aligned-spin effective-one-body waveforms to significantly speed up the calculations. We explore the phenomenology of the measurement accuracies for binaries with total masses between 50M(⊙) and 500M(⊙) and mass ratios between 0.1 and 1. We find that (i) at total masses below ∼200M(⊙), where the signal-to-noise ratio is dominated by the inspiral portion of the signal, the chirp mass parameter can be accurately measured; (ii) at higher masses, the information content is dominated by the ringdown, and total mass is measured more accurately; (iii) the mass of the lower-mass companion is poorly estimated, especially at high total mass and more extreme mass ratios; and (iv) spin cannot be accurately measured for our injection set with nonspinning components. Most importantly, we find that for binaries with nonspinning components at all values of the mass ratio in the considered range and at a network signal-to-noise ratio of 15, analyzed with spin-aligned templates, the presence of an intermediate-mass black hole with mass >100M(⊙) can be confirmed with 95% confidence in any binary that includes a component with a mass of 130M(⊙) or greater.

The Metallicity Evolution of Low Mass Galaxies: New Contraints at Intermediate Redshift

Science.gov (United States)

Henry, Alaina; Martin, Crystal L.; Finlator, Kristian; Dressler, Alan

2013-01-01

We present abundance measurements from 26 emission-line-selected galaxies at z approx. 0.6-0.7. By reaching stellar masses as low as 10(exp 8) M stellar mass, these observations provide the first measurement of the intermediate-redshift mass-metallicity (MZ) relation below 10(exp 9)M stellar mass. For the portion of our sample above M is greater than 10(exp 9)M (8/26 galaxies), we find good agreement with previous measurements of the intermediate-redshift MZ relation. Compared to the local relation, we measure an evolution that corresponds to a 0.12 dex decrease in oxygen abundances at intermediate redshifts. This result confirms the trend that metallicity evolution becomes more significant toward lower stellar masses, in keeping with a downsizing scenario where low-mass galaxies evolve onto the local MZ relation at later cosmic times. We show that these galaxies follow the local fundamental metallicity relation, where objects with higher specific (mass-normalized) star formation rates (SFRs) have lower metallicities. Furthermore, we show that the galaxies in our sample lie on an extrapolation of the SFR-M* relation (the star-forming main sequence). Leveraging the MZ relation and star-forming main sequence (and combining our data with higher-mass measurements from the literature), we test models that assume an equilibrium between mass inflow, outflow, and star formation.We find that outflows are required to describe the data. By comparing different outflow prescriptions, we show that momentum, driven winds can describe the MZ relation; however, this model underpredicts the amount of star formation in low-mass galaxies. This disagreement may indicate that preventive feedback from gas heating has been overestimated, or it may signify a more fundamental deviation from the equilibrium assumption.

Deeply inelastic collisions as a source of intermediate mass fragments at E/A = 27 MeV

International Nuclear Information System (INIS)

Borderie, B.; Montoya, M.; Rivet, M.F.; Jouan, D.; Cabot, C.; Fuchs, H.; Gardes, D.; Gauvin, H.; Jacquet, D.; Monnet, F.

1988-01-01

Intermediate-mass fragments detected in coincidence with heavy residues were measured in 40 Ar induced reactions on Ag at E/A = 27 MeV. From the observed characteristics, it is inferred that intermediate-mass fragments associated with the so-called intermediate-velocity source come mainly from deeply inelastic collisions occurring after or at the same time as preequilibrium particle emission. (orig.)

Development of a plug-type IMS-MS instrument and its applications in resolving problems existing in in-situ detection of illicit drugs and explosives by IMS.

Science.gov (United States)

Du, Zhenxia; Sun, Tangqiang; Zhao, Jianan; Wang, Di; Zhang, Zhongxia; Yu, Wenlian

2018-07-01

Ion mobility spectrometry (IMS) which acts as a rapid analysis technique is widely used in the field detection of illicit drugs and explosives. Due to limited separation abilities of the pint-sized IMS challenges and problems still exist regarding high false positive and false negative responses due to the interference of the matrix. In addition, the gas-phase ion chemistry and special phenomena in the IMS spectra, such one substance showing two peaks, were not identified unambiguously. In order to explain or resolve these questions, in this paper, an ion mobility spectrometry was coupled to a mass spectrometry (IMS-MS). A commercial IMS is embedded in a custom-built ion chamber shell was attached to the mass spectrometer. The faraday plate of IMS was fabricated with a hole for the ions to passing through to the mass spectrometer. The ion transmission efficiency of IMS-MS was optimized by optimizing the various parameters, especially the distance between the faraday plate and the cone of mass spectrum. This design keeps the integrity of the two original instruments and the mass spectrometry still works with multimode ionization source (i.e., IMS-MS, ESI-MS, APCI-MS modes). The illicit drugs and explosive samples were analyzed by the IMS-MS with 63 Ni source. The results showed that the IMS-MS is of high sensitivity. The ionization mechanism of the illicit drug and explosive samples with 63 Ni source were systematically studied. In addition, the interferent which interfered the detection of cocaine was identified as dibutyl phthalate (DBP) by this platform. The reason why the acetone solution of amphetamine showed two peaks was explained. Copyright © 2018 Elsevier B.V. All rights reserved.

Transiting exoplanets from the CoRoT space mission. XXIII. CoRoT-21b: a doomed large Jupiter around a faint subgiant star

DEFF Research Database (Denmark)

Pätzold, M.; Endl, M.; Csizmadia, Sz.

2012-01-01

-up observations, however, were performed mainly by the 10-m Keck telescope in January 2010. The companion CoRoT-21b is a Jupiter-like planet of 2.26 ± 0.33 Jupiter masses and 1.30 ± 0.14 Jupiter radii in an circular orbit of semi-major axis 0.0417 ± 0.0011 AU and an orbital period of 2.72474 ± 0.00014 days....... The planetary bulk density is (1.36   ±   0.48) × 103 kg m-3, very similar to the bulk density of Jupiter, and follows an M1/3 − R relation like Jupiter. The F8IV star is a sub-giant star of 1.29 ± 0.09 solar masses and 1.95 ± 0.2 solar radii. The star and the planet exchange extremetidal forces that will lead...

Search for Gravitational Waves from Intermediate Mass Binary Black Holes

Science.gov (United States)

Blackburn, L.; Camp, J. B.; Cannizzo, J.; Stroeer, A. S.

2012-01-01

We present the results of a weakly modeled burst search for gravitational waves from mergers of non-spinning intermediate mass black holes (IMBH) in the total mass range 100-450 solar Mass and with the component mass ratios between 1:1 and 4:1. The search was conducted on data collected by the LIGO and Virgo detectors between November of 2005 and October of 2007. No plausible signals were observed by the search which constrains the astrophysical rates of the IMBH mergers as a function of the component masses. In the most efficiently detected bin centered on 88 + 88 solar Mass , for non-spinning sources, the rate density upper limit is 0.13 per Mpc(exp 3) per Myr at the 90% confidence level.

Radio Detections During Two State Transitions of the Intermediate-Mass Black Hole HLX-1

Science.gov (United States)

Webb, Natalie; Cseh, David; Lenc, Emil; Godet, Olivier; Barret, Didier; Corbel, Stephane; Farrell, Sean; Fender, Robert; Gehrels, Neil; Heywood, Ian

2012-01-01

Relativistic jets are streams of plasma moving at appreciable fractions of the speed of light. They have been observed from stellar-mass black holes (approx. 3 to 20 solar masses) as well as supermassive black holes (approx.. 10(exp 6) to 10(exp 9) Solar Mass) found in the centers of most galaxies. Jets should also be produced by intermediate-mass black holes (approx. 10(exp 2) to 10(exp 5) Solar Mass), although evidence for this third class of black hole has, until recently, been weak. We report the detection of transient radio emission at the location of the intermediate-mass black hole candidate ESO 243-49 HLX-1, which is consistent with a discrete jet ejection event. These observations also allow us to refine the mass estimate of the black hole to be between approx. 9 × 10(exp 3) Solar Mass and approx. 9 × 10(exp 4) Solar Mass.

Ultra-luminous X-ray sources and intermediate-mass black holes

International Nuclear Information System (INIS)

Cseh, David

2012-01-01

More than ten years ago, the discovery of Ultra-luminous X-ray sources (ULXs) has opened up an entirely new field in astrophysics. Many ideas were developed to explain the nature of these sources, like their emission mechanism, mass, and origin, without any strong conclusions. Their discovery boosted the fields of X-ray binaries, accretion physics, stellar evolution, cosmology, black hole formation and growth, due to the concept of intermediate-mass black holes (IMBHs). Since their discovery is related to the domain of X-ray astrophysics, there have been very few studies made in other wavelengths. This thesis focuses on the multiwavelength nature of Ultra-luminous X-ray sources and intermediate-mass black holes from various aspects, which help to overcome some difficulties we face today. First, I investigated the accretion signatures of a putative intermediate-mass black hole in a particular globular cluster. To this purpose, I characterized the nature of the innermost X-ray sources in the cluster. Then I calculated an upper limit on the mass of the black hole by studying possible accretion efficiencies and rates based on the dedicated X-ray and radio observations. The accreting properties of the source was described with standard spherical accretion and in the context of inefficient accretion. Secondly, I attempted to dynamically measure the mass of the black hole in a particular ULX via optical spectroscopy. I discovered that a certain emission line has a broad component that markedly shifts in wavelength. I investigated the possibility whether this line originates in the accretion disk, and thus might trace the orbital motion of the binary system. I also characterized the parameters of the binary system, such as the mass function, possible orbital separation, the size of the line-emitting region, and an upper limit on the mass of the black hole. Then I studied the environment of a number of ULXs that are associated with large-scale optical and radio nebulae. I

Black holes evaporation and big mass particle (maximon, intermediate boson) creation in nonstationary universe

International Nuclear Information System (INIS)

Man'ko, V.I.; Markov, M.A.

1984-01-01

This chapter considers the process of creation of particles with maximally big masses (maximons, intermediate bosons) in the nonstationary Universe within the framework of neutral and charged scalar field theory. The conclusions of the matter creation model for real particles (resonances) and hypothetical particles (maximons, friedmons, intermediate bosons) are analyzed. It is determined that if the mechanism of maximon's creation exists, then these particles must be stable. The maximons could be the final states of decaying black holes. A possible mechanism of cosmic ray creation as a result of ''vacuum'' generation of known unstable particles is discussed. The limits upon the mass and the life time of intermediate bosons are calculated. It is demonstrated that the creation of masses greater than 10 GeV, and with life times less than 10- 24 sec and quantity of elementary particles greater than 100 are in contradiction with the particle creation mechanism and the experimental mass density in the Universe. The formalism of the examined method and its vacuum properties are discussed in an appendix

Tidal disruption of white dwarfs by intermediate mass black holes

Directory of Open Access Journals (Sweden)

Bode T.

2012-12-01

Full Text Available Modeling ultra-close encounters between a white dwarf and a spinning, intermediate mass black hole requires a full general relativistic treatment of gravity. This paper summarizes results from such a study. Our results show that the disruption process and prompt accretion of the debris strongly depend on the magnitude and orientation of the black hole spin. On the other hand, the late-time accretion onto the black hole follows the same decay, Ṁ ∝  t−5/3, estimated from Newtonian gravity disruption studies. The spectrum of the fallback material peaks in the soft X-rays and sustains Eddington luminosity for 1–3 yrs after the disruption. The orientation of the black hole spin has also a profound effect on how the outflowing debris obscures the central region. The disruption produces a burst of gravitational radiation with characteristic frequencies of ∼3.2 Hz and strain amplitudes of ∼10−18 for galactic intermediate mass black holes.

The Characterization of Laser Ablation Patterns and a New Definition of Resolution in Matrix Assisted Laser Desorption Ionization Imaging Mass Spectrometry (MALDI-IMS).

Science.gov (United States)

O'Rourke, Matthew B; Raymond, Benjamin B A; Padula, Matthew P

2017-05-01

Matrix assisted laser desorption ionization imaging mass spectrometry (MALDI-IMS) is a technique that has seen a sharp rise in both use and development. Despite this rapid adoption, there have been few thorough investigations into the actual physical mechanisms that underlie the acquisition of IMS images. We therefore set out to characterize the effect of IMS laser ablation patterns on the surface of a sample. We also concluded that the governing factors that control spatial resolution have not been correctly defined and therefore propose a new definition of resolution. Graphical Abstract ᅟ.

Intermediate Syndrome Following Organophosphate Insecticide Poisoning

Directory of Open Access Journals (Sweden)

Chen-Chang Yang

2007-11-01

Full Text Available Acute organophosphate insecticide poisoning can manifest 3 different phases of toxic effects, namely, acute cholinergic crisis, intermediate syndrome (IMS, and delayed neuropathy. Among them, IMS has been considered as a major contributing factor of organophosphate-related morbidity and mortality because of its frequent occurrence and probable consequence of respiratory failure. Despite a high incidence, the pathophysiology that underlies IMS remains unclear. Previously proposed mechanisms of IMS include different susceptibility of various cholinergic receptors, muscle necrosis, prolonged acetylcholinesterase inhibition, inadequate oxime therapy, downregulation or desensitization of postsynaptic acetylcholine receptors, failure of postsynaptic acetylcholine release, and oxidative stress-related myopathy. The clinical manifestations of IMS typically occur within 24 to 96 hours, affecting conscious patients without cholinergic signs, and involve the muscles of respiration, proximal limb muscles, neck flexors, and muscles innervated by motor cranial nerves. With appropriate therapy that commonly includes artificial respiration, complete recovery develops 5–18 days later. Patients with atypical manifestations of IMS, especially a relapse or a continuum of acute cholinergic crisis, however, were frequently reported in clinical studies of IMS. The treatment of IMS is mainly supportive. Nevertheless, because IMS generally concurs with severe organophosphate toxicity and persistent inhibition of acetylcholinesterase, early aggressive decontamination, appropriate antidotal therapy, and prompt institution of ventilatory support should be helpful in ameliorating the magnitude and/or the incidence of IMS. Although IMS is well recognized as a disorder of neuromuscular junctions, its exact etiology, incidence, and risk factors are not clearly defined because existing studies are largely small-scale case series and do not employ a consistent and rigorous

Neutrino masses in the SO(10) model with intermediate stage of the symmetry breaking

International Nuclear Information System (INIS)

Svetovoj, V.B.

1982-01-01

An effect for the neutrino masses of an intermediate stage in the symmetry spontaneous breaking, different from SU(5), is investigated in some detail for the SO(1O) model. There are two possibilities depending on the composition of the Higgs sector: i) msub(ν) approximately msub(f)(Msub(W)/Msub(1)); ii) msub(ν) approximately msub(f)sub(b)/Msub(1))(M/Msub(1)), where M, M 1 and Msub) are the scales of the breaking of the original SO(10) simmetry, the intermediate symmetry, and the standard SUsub(c)(3)xSUsub(L)(2)xU(1) symmetry, respectively, and msub(f) is a typical fermion mass. It as shown that a Majorana mass of the right neutrino (νsub(R)) of a purely loop origin would result in a too large mass of the usual neutrinos, so a tree-graph contribution to the mass of νsub(R) is necessary. Numerical estimates for the neutrino masses are discussed [ru

Coincidence measurements of intermediate mass fragments produced in /sup 32/S-induced reactions on Ag at E/A = 22.5 MeV

International Nuclear Information System (INIS)

Fields, D.J.; Lynch, W.G.; Nayak, T.K.

1986-01-01

Single- and two-particle inclusive cross sections for the production of light nuclei and intermediate mass fragments, 3< or =Z< or =24, were measured at angles well beyond the grazing angle for /sup 32/S-induced reactions on Ag at 720 MeV. Information about fragment multiplicities and reaction dynamics was extracted from measurements of light particles, intermediate mass fragments, and targetlike residues in coincidence with intermediate mass fragments. Incomplete linear momentum transfer and non-compound-particle emission are important features of collisions producing intermediate mass fragments. About half of the incident kinetic energy in these collisions is converted into internal excitation. The mean multiplicity of intermediate mass fragments is of the order of 1. Particle correlations are strongly enhanced in the plane which contains the intermediate mass fragment and the beam axis

The spectrum of intermediate syndrome following acute organophosphate poisoning: a prospective cohort study from Sri Lanka.

Directory of Open Access Journals (Sweden)

Pradeepa Jayawardane

2008-07-01

Full Text Available Intermediate syndrome (IMS is a major cause of death from respiratory failure following acute organophosphate poisoning. The objective of this study was to determine repetitive nerve stimulation (RNS predictors of IMS that would assist in patient management and clinical research.Seventy-eight consenting symptomatic patients with organophosphate poisoning were assessed prospectively with daily physical examination and RNS. RNS was done on the right and left median and ulnar nerves at 1, 3, 10, 15, 20, and 30 Hz. The study was conducted as a prospective observational cohort study in the Central Province, Sri Lanka. IMS was diagnosed in ten out of 78 patients using a priori clinical diagnostic criteria, and five of them developed respiratory failure. All ten patients showed progressive RNS changes correlating with the severity of IMS. A decrement-increment was observed at intermediate and high frequencies preceding the onset of clinical signs of IMS. As the patient developed clinical signs of IMS, decrement-increment was progressively noted at low and intermediate frequencies and a combination of decrement-increment and repetitive fade or severe decrement was noted at high frequencies. Severe decrement preceded respiratory failure in four patients. Thirty patients developed forme fruste IMS with less severe weakness not progressing to respiratory failure whose RNS was characterized by decrement-increment or a combination of decrement-increment and repetitive fade but never severe decrements.Characteristic changes in RNS, preceding the development of IMS, help to identify a subgroup of patients at high risk of developing respiratory failure. The forme fruste IMS with the characteristic early changes on RNS indicates that IMS is a spectrum disorder. RNS changes are objective and precede the diagnosis and complications of IMS. Thus they may be useful in clinical management and research.

Utility of imaging mass spectrometry (IMS) by matrix-assisted laser desorption ionization (MALDI) on an ion trap mass spectrometer in the analysis of drugs and metabolites in biological tissues.

Science.gov (United States)

Drexler, Dieter M; Garrett, Timothy J; Cantone, Joseph L; Diters, Richard W; Mitroka, James G; Prieto Conaway, Maria C; Adams, Stephen P; Yost, Richard A; Sanders, Mark

2007-01-01

The properties and potential liabilities of drug candidate are investigated in detailed ADME assays and in toxicity studies, where findings are placed in context of exposure to dosed drug and metabolites. The complex nature of biological samples may necessitate work-up procedures prior to high performance liquid chromatography-mass spectrometric (HPLC-MS) analysis of endogenous or xenobiotic compounds. This concept can readily be applied to biological fluids such as blood or urine, but in localized samples such as organs and tissues potentially important spatial, thus anatomical, information is lost during sample preparation as the result of homogenization and extraction procedures. However, the localization of test article or spatial identification of metabolites may be critical to the understanding of the mechanism of target-organ toxicity and its relevance to clinical safety. Tissue imaging mass spectrometry (IMS) by matrix-assisted laser desorption ionization (MALDI) and ion trap mass spectrometry (MS) with higher order mass spectrometric scanning functions was utilized for localization of dosed drug or metabolite in tissue. Laser capture microscopy (LCM) was used to obtain related samples from tissue for analyses by standard MALDI-MS and HPLC-MS. In a toxicology study, rats were administered with a high dosage of a prodrug for 2 weeks. Birefringent microcrystalline material (10-25 microm) was observed in histopathologic formalin-fixed tissue samples. Direct analysis by IMS provided the identity of material in the microcrystals as circulating active drug while maintaining spatial orientation. Complementary data from visual cross-polarized light microscopy as well as standard MALDI-MS and HPLC-MS experiments on LCM samples validated the qualitative results obtained by IMS. Furthermore, the HPLC-MS analysis on the LCM samples afforded a semi-quantitative assessment of the crystalline material in the tissue samples. IMS by MALDI ion trap MS proved sensitive

Synchrotron photoionization mass spectrometry study of intermediates in fuel-rich 1,2-dimethoxyethane flame

International Nuclear Information System (INIS)

Lin, Z. K.; Han, D. L.; Li, S. F.; Li, Y. Y.; Yuan, T.

2009-01-01

Intermediates in a fuel-rich premixed laminar 1,2-dimethoxyethane (DME) flame are studied by molecular beam mass spectrometry combined with tunable synchrotron vacuum ultraviolet photoionization. About 30 intermediate species are identified in the present work, and their mole fraction profiles are evaluated. The experimental results show that the formations of intermediates, both hydrocarbons and oxygenated hydrocarbons, are closely linked to the structure of fuel, which is consistent with the previous reports. Species produced from H atom abstraction and beta scission of DME usually have much higher concentrations than others. The oxygen atoms in DME are considered to act as partitions of the primary intermediates; therefore farther reactions among these primary intermediates are difficult to occur, resulting in absence of most large intermediate species.

Searching for intermediate-mass black holes via optical variability

Science.gov (United States)

Adler-Levine, Ryan; Moran, Edward C.; Kay, Laura

2018-01-01

A handful of nearby dwarf galaxies with intermediate-mass black holes (IMBHs) in their nuclei display significant optical variability on short timescales. To investigate whether dwarf galaxy AGNs as a class exhibit similar variability, we have monitored a sample of low-mass galaxies that possess spectroscopically confirmed type 1 AGNs. However, because of the variations in seeing, focus, and guiding errors that occur in images taken at different epochs, analyses based on aperture photometry are ineffective. We have thus developed a new method for matching point-spread functions in images that permits use of image subtraction photometry techniques. Applying this method to our photometric data, we have confirmed that several galaxies with IMBHs are indeed variable, which suggests that variability can be used to search for IMBHs in low-mass galaxies whose emission-line properties are ambiguous.

Fragment mass distribution of proton-induced spallation reaction with intermediate energy

International Nuclear Information System (INIS)

Fan Sheng; Ye Yanlin; Xu Chuncheng; Chen Tao; Sobolevsky, N.M.

2000-01-01

The test of part benchmark of SHIELD code is finished. The fragment cross section and mass distribution and excitation function of the residual nuclei from proton-induced spallation reaction on thin Pb target with intermediate energy have been calculated by SHIELD code. And the results are in good agreement with measured data. The fragment mass distribution of the residual nuclei from proton-induced spallation reaction on thick Pb target with incident energy 1.6 GeV have been simulated

A PRECISE MASS MEASUREMENT OF THE INTERMEDIATE-MASS BINARY PULSAR PSR J1802 - 2124

International Nuclear Information System (INIS)

Ferdman, R. D.; Cognard, I.; Desvignes, G.; Theureau, G.; Stairs, I. H.; Kramer, M.; McLaughlin, M. A.; Lorimer, D. R.; Nice, D. J.; Manchester, R. N.; Hobbs, G.; Lyne, A. G.; Faulkner, A.; Camilo, F.; Possenti, A.; Demorest, P. B.; Backer, D. C.

2010-01-01

PSR J1802 - 2124 is a 12.6 ms pulsar in a 16.8 hr binary orbit with a relatively massive white dwarf (WD) companion. These properties make it a member of the intermediate-mass class of binary pulsar (IMBP) systems. We have been timing this pulsar since its discovery in 2002. Concentrated observations at the Green Bank Telescope, augmented with data from the Parkes and Nancay observatories, have allowed us to determine the general relativistic Shapiro delay. This has yielded pulsar and WD mass measurements of 1.24 ± 0.11 M sun and 0.78 ± 0.04 M sun (68% confidence), respectively. The low mass of the pulsar, the high mass of the WD companion, the short orbital period, and the pulsar spin period may be explained by the system having gone through a common-envelope phase in its evolution. We argue that selection effects may contribute to the relatively small number of known IMBPs.

Neutrino masses in an SO(10) model with an intermediate stage of symmetry breaking

International Nuclear Information System (INIS)

Svetovoi, V.B.

1982-01-01

The effect on neutrino masses of an intermediate stage in symmetry breaking different from SU(5) is investigated in detail for the SO(10) model. There are two possibilities depending on the contents of the Higgs sector: i) m/sub ν/approx.m/sub f/(M/sub W//M 1 ); ii) m/sub ν/approx.m/sub f/(M/sub W//M 1 )(M/M 1 ), where M, M 1 and M/sub W/ are the scales of the breaking of the original SO(10) symmetry, the intermediate symmetry, and the standard SU/sub c/(3) x SU/sub L/(2) x U(1) symmetry, respectively, and m/sub f/ is a typical fermion mass. It is shown that a Majorana mass of the right-handed-neutrino (ν/sub R/) of a purely loop origin would result in too large a mass of the usual neutrinos, so a tree-graph contribution to the mass of ν/sub R/ is necessary. Numerical estimates for the neutrino masses are discussed

KEPLER-21b: A 1.6 R{sub Earth} PLANET TRANSITING THE BRIGHT OSCILLATING F SUBGIANT STAR HD 179070

Energy Technology Data Exchange (ETDEWEB)

Howell, Steve B. [National Optical Astronomy Observatory, Tucson, AZ 85719 (United States); Rowe, Jason F.; Bryson, Stephen T. [NASA Ames Research Center, Moffett Field, CA 94035 (United States); Quinn, Samuel N. [Harvard-Smithsonian Center for Astrophysics, Cambridge, MA 02138 (United States); Marcy, Geoffrey W.; Isaacson, Howard [Department of Astronomy, University of California, Berkeley, CA 94720 (United States); Ciardi, David R. [NASA Exoplanet Science Institute/Caltech, Pasadena, CA 91125 (United States); Chaplin, William J.; Elsworth, Yvonne [School of Physics and Astronomy, University of Birmingham, Edgbaston, Birmingham B15 2TT (United Kingdom); Metcalfe, Travis S. [High Altitude Observatory and Scientific Computing Division, National Center for Atmospheric Research, Boulder, CO 80307 (United States); Monteiro, Mario J. P. F. G. [Centro de Astrofisica, Universidade do Porto, Rua das Estrelas, 4150-762 Porto (Portugal); Appourchaux, Thierry [Institut d' Astrophysique Spatiale, Universite Paris XI-CNRS (UMR8617), Batiment 121, 91405 Orsay Cedex (France); Basu, Sarbani [Department of Astronomy, Yale University, New Haven, CT 06520-8101 (United States); Creevey, Orlagh L. [Departamento de Astrofisica, Universidad de La Laguna, E-38206 La Laguna, Tenerife (Spain); Gilliland, Ronald L. [Space Telescope Science Institute, Baltimore, MD 21218 (United States); Quirion, Pierre-Olivier [Canadian Space Agency, 6767 Boulevard de l' Aeroport, Saint-Hubert, QC, J3Y 8Y9 (Canada); Stello, Denis [Sydney Institute for Astronomy (SIfA), School of Physics, University of Sydney, NSW 2006 (Australia); Kjeldsen, Hans; Christensen-Dalsgaard, Joergen [Department of Physics and Astronomy, Aarhus University, DK-8000 Aarhus C (Denmark); Garcia, Rafael A. [Laboratoire AIM, CEA/DSM-CNRS-Universite Paris Diderot-IRFU/SAp, 91191 Gif-sur-Yvette Cedex (France); and others

2012-02-20

We present Kepler observations of the bright (V = 8.3), oscillating star HD 179070. The observations show transit-like events which reveal that the star is orbited every 2.8 days by a small, 1.6 R{sub Earth} object. Seismic studies of HD 179070 using short cadence Kepler observations show that HD 179070 has a frequency-power spectrum consistent with solar-like oscillations that are acoustic p-modes. Asteroseismic analysis provides robust values for the mass and radius of HD 179070, 1.34 {+-} 0.06 M{sub Sun} and 1.86 {+-} 0.04 R{sub Sun }, respectively, as well as yielding an age of 2.84 {+-} 0.34 Gyr for this F5 subgiant. Together with ground-based follow-up observations, analysis of the Kepler light curves and image data, and blend scenario models, we conservatively show at the >99.7% confidence level (3{sigma}) that the transit event is caused by a 1.64 {+-} 0.04 R{sub Earth} exoplanet in a 2.785755 {+-} 0.000032 day orbit. The exoplanet is only 0.04 AU away from the star and our spectroscopic observations provide an upper limit to its mass of {approx}10 M{sub Earth} (2{sigma}). HD 179070 is the brightest exoplanet host star yet discovered by Kepler.

Hydrogen-antihydrogen oscillations: Signature of intermediate mass scales in GUTs

Directory of Open Access Journals (Sweden)

Uptal Sarkar

1983-01-01

Full Text Available Hydrogen-antihydrogen oscillations and the double nucleon decay (pp, np and nn into two antileptons are discussed in the context of SO(10, E(6 and SU(16 GUTs. It is shown that the intermediate mass scales of the GUTs concerned govern the amplitude of these processes which are found to compete with the other baryon nonconserving processes in SU(16 GUT.

CHARACTERIZING TWO SOLAR-TYPE KEPLER SUBGIANTS WITH ASTEROSEISMOLOGY: KIC 10920273 AND KIC 11395018

International Nuclear Information System (INIS)

Doğan, G.; Metcalfe, T. S.; Mathur, S.; Deheuvels, S.; Pinsonneault, M.; Di Mauro, M. P.; Eggenberger, P.; Creevey, O. L.; Monteiro, M. J. P. F. G.; Sousa, S. G.; Brandão, I. M.; Campante, T. L.; Frasca, A.; Karoff, C.; Handberg, R.; Thygesen, A. O.; Bruntt, H.; Biazzo, K.; Niemczura, E.; Bedding, T. R.

2013-01-01

Determining fundamental properties of stars through stellar modeling has improved substantially due to recent advances in asteroseismology. Thanks to the unprecedented data quality obtained by space missions, particularly CoRoT and Kepler, invaluable information is extracted from the high-precision stellar oscillation frequencies, which provide very strong constraints on possible stellar models for a given set of classical observations. In this work, we have characterized two relatively faint stars, KIC 10920273 and KIC 11395018, using oscillation data from Kepler photometry and atmospheric constraints from ground-based spectroscopy. Both stars have very similar atmospheric properties; however, using the individual frequencies extracted from the Kepler data, we have determined quite distinct global properties, with increased precision compared to that of earlier results. We found that both stars have left the main sequence and characterized them as follows: KIC 10920273 is a one-solar-mass star (M = 1.00 ± 0.04 M ☉ ), but much older than our Sun (t = 7.12 ± 0.47 Gyr), while KIC 11395018 is significantly more massive than the Sun (M = 1.27 ± 0.04 M ☉ ) with an age close to that of the Sun (t = 4.57 ± 0.23 Gyr). We confirm that the high lithium abundance reported for these stars should not be considered to represent young ages, as we precisely determined them to be evolved subgiants. We discuss the use of surface lithium abundance, rotation, and activity relations as potential age diagnostics.

Lesmes, Daniel; Cabello, Gabriel; Massó Castilla, Jordi (Coords.: Georges Didi-Huberman. Imágenes, historia, pensamiento

Directory of Open Access Journals (Sweden)

Juan Jesús Torres

2017-01-01

Full Text Available Coordinado por Daniel Lesmes (Universidad Complutense de Madrid, Gabriel Cabello (Universidad de Granada y Jordi Massó Castilla (Universidad Complutense de Madrid, el número 246 de la revista Anthropos está íntegramente dedicado al pensamiento de Georges Didi-Huberman (Saint-Étienne, 1953, investigador de innegable trascendencia en el estudio sobre las imágenes y cuya recuperación del legado de Aby Warburg ha situado a la historia del arte ante un necesario replanteamiento de sus conceptos originarios, llevando, además, la reflexión sobre las imágenes a una nueva dimensión ética, emocional y gestual. Imágenes traidoras, en aquel sentido de Magritte, insostenibles sin la presencia de otros saberes diferentes y a priori dispares como la propia historia del arte, el psicoanálisis, la filosofía posestructuralista y la antropología. Desentrañar las relaciones que como seres culturales mantenemos con ellas ha sido el motivo del trabajo de Didi-Huberman, capaz de mostrar la importancia de esa dependencia revelando nuestra esgrima con el pasado y, de esta manera, nuestro trato con el presente, su legitimación y las posibilidades de transformación que este ofrece.

Measurement of mass distribution of U-235 fission products in the intermediate neutron region

International Nuclear Information System (INIS)

Nakagomi, Yoshihiro; Kobayashi, Shohei; Yamamoto, Shuji; Kanno, Ikuo; Wakabayashi, Hiroaki.

1982-01-01

The mass distribution and the momentum distribution of U-235 fission products in the intermediate neutron region were measured by using a combination system of the Yayoi intermediate neutron column and an electron linear accelerator. The double energy measurement method was applied. A fission chamber, which consists of an enriched uranium target and two Si surface barrier detectors, was used for the measurement of the neutrons with energy above 1.3 eV. The linear accelerator was operated at the repetition rate of 100 Hz and the pulse width of 10 ns. The data obtained by the two-dimensional pulse height analysis were analyzed by the Schmitt's method. The preliminary results of the mass distribution and the momentum distribution of fission fragments were obtained. (Kato, T.)

Synthesis of Cyclic Py-Im Polyamide Libraries

OpenAIRE

Li, Benjamin C.; Montgomery, David C.; Puckett, James W.; Dervan, Peter B.

2013-01-01

Cyclic Py-Im polyamides containing two GABA turn units exhibit enhanced DNA binding affinity, but extensive studies of their biological properties have been hindered due to synthetic inaccessibility. A facile modular approach toward cyclic polyamides has been developed via microwave-assisted solid-phase synthesis of hairpin amino acid oligomer intermediates followed by macrocyclization. A focused library of cyclic polyamides 1–7 targeted to the androgen response element (ARE) and the estrogen...

Radio Observations of Ultra-Luminous X-Ray Sources ---Microblazars or Intermediate-Mass Black Holes?---

Science.gov (United States)

Körding, E.; Colbert, E.; Falcke, H.

In recent years Ultra-Luminous X-Ray sources (ULXs) received wide attention, however, their true nature is not yet understood. Many explanations have been suggested, including intermediate-mass black holes, super-Eddington accretion flows, anisotropic emission, and relativistic beaming of microquasars. We model the logN-logS distribution of ULXs assuming that each neutron star or black hole XRB can be described by an accretion disk plus jet model, where the jet is relativistically beamed. The distribution can be either fit by intermediate-mass black holes or by stellar mass black holes with mildly relativistic jets. Even though the jet is intrinsically weaker than the accretion disk, relativistic beaming can in the latter approach lead to the high fluxes observed. To further explore the possibility of microblazars contributing to the ULX phenomenon, we have embarked on a radio-monitoring study of ULXs in nearby galaxies with the VLA. However, up to now no radio flare has been detected. Using the radio/X-ray correlation the upper limits on the radio flux can be converted into upper limits for the black hole masses of MBH ≲ 10^3 M⊙.

Critical masses of bare homogeneous spherical UO2-water mixtures at intermediate enrichments

International Nuclear Information System (INIS)

Rendon, G.L.; Stratton, W.

1999-01-01

Critical masses of bare homogeneous spherical UO 2 -water mixtures at various intermediate fissile enrichments determined by multigroup, transport theory is presented. This work was performed to provide support for particular issues encountered by the nuclear industry when operating in the intermediate enrichment regime, namely, the validation of codes used to set criticality safety limits. Validation is normally performed with a comparison of computational results and applicable experiments. However, this may be difficult in some cases because of the lack of sufficient applicable experiments in the intermediate enrichment range. If a large extension of the area of applicability from an experiment to the desired application exists, then an alternative means for validation must be employed. Ideal interpretations of standard ANSI/ANS 8.1 Section 4.3 (1983) implies that perhaps an independent code and data system may be employed for validation purposes

A Unique (3+2) Annulation Reaction between Meldrum's Acid and Nitrones: Mechanistic Insight by ESI-IMS-MS and DFT Studies.

Science.gov (United States)

Lespes, Nicolas; Pair, Etienne; Maganga, Clisy; Bretier, Marie; Tognetti, Vincent; Joubert, Laurent; Levacher, Vincent; Hubert-Roux, Marie; Afonso, Carlos; Loutelier-Bourhis, Corinne; Brière, Jean-François

2018-03-15

The fragile intermediates of the domino process leading to an isoxazolidin-5-one, triggered by unique reactivity between Meldrum's acid and an N-benzyl nitrone in the presence of a Brønsted base, were determined thanks to the softness and accuracy of electrospray ionization mass spectrometry coupled to ion mobility spectrometry (ESI-IMS-MS). The combined DFT study shed light on the overall organocatalytic sequence that starts with a stepwise (3+2) annulation reaction that is followed by a decarboxylative protonation sequence encompassing a stereoselective pathway issue. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

A MULTIPLICITY CENSUS OF INTERMEDIATE-MASS STARS IN SCORPIUS-CENTAURUS

International Nuclear Information System (INIS)

Janson, Markus; Lafrenière, David; Jayawardhana, Ray; Bonavita, Mariangela; Girard, Julien H.; Brandeker, Alexis; Gizis, John E.

2013-01-01

Stellar multiplicity properties have been studied for the lowest and the highest stellar masses, but intermediate-mass stars from F-type to late A-type have received relatively little attention. Here, we report on a Gemini/NICI snapshot imaging survey of 138 such stars in the young Scorpius-Centaurus (Sco-Cen) region, for the purpose of studying multiplicity with sensitivity down to planetary masses at wide separations. In addition to two brown dwarfs and a companion straddling the hydrogen-burning limit which we reported previously, here we present 26 new stellar companions and determine a multiplicity fraction within 0.''1-5.''0 of 21% ± 4%. Depending on the adopted semimajor axis distribution, our results imply a total multiplicity in the range of ∼60%-80%, which further supports the known trend of a smooth continuous increase in the multiplicity fraction as a function of primary stellar mass. A surprising feature in the sample is a distinct lack of nearly equal-mass binaries, for which we discuss possible reasons. The survey yielded no additional companions below or near the deuterium-burning limit, implying that their frequency at >200 AU separations is not quite as high as might be inferred from previous detections of such objects within the Sco-Cen region

Single-molecule studies of the Im7 folding landscape.

Science.gov (United States)

Pugh, Sara D; Gell, Christopher; Smith, D Alastair; Radford, Sheena E; Brockwell, David J

2010-04-23

Under appropriate conditions, the four-helical Im7 (immunity protein 7) folds from an ensemble of unfolded conformers to a highly compact native state via an on-pathway intermediate. Here, we investigate the unfolded, intermediate, and native states populated during folding using diffusion single-pair fluorescence resonance energy transfer by measuring the efficiency of energy transfer (or proximity or P ratio) between pairs of fluorophores introduced into the side chains of cysteine residues placed in the center of helices 1 and 4, 1 and 3, or 2 and 4. We show that while the native states of each variant give rise to a single narrow distribution with high P values, the distributions of the intermediates trapped at equilibrium (denoted I(eqm)) are fitted by two Gaussian distributions. Modulation of the folding conditions from those that stabilize the intermediate to those that destabilize the intermediate enabled the distribution of lower P value to be assigned to the population of the unfolded ensemble in equilibrium with the intermediate state. The reduced stability of the I(eqm) variants allowed analysis of the effect of denaturant concentration on the compaction and breadth of the unfolded state ensemble to be quantified from 0 to 6 M urea. Significant compaction is observed as the concentration of urea is decreased in both the presence and absence of sodium sulfate, as previously reported for a variety of proteins. In the presence of Na(2)SO(4) in 0 M urea, the P value of the unfolded state ensemble approaches that of the native state. Concurrent with compaction, the ensemble displays increased peak width of P values, possibly reflecting a reduction in the rate of conformational exchange among iso-energetic unfolded, but compact conformations. The results provide new insights into the initial stages of folding of Im7 and suggest that the unfolded state is highly conformationally constrained at the outset of folding. (c) 2010 Elsevier Ltd. All rights reserved.

Transitional Disks Associated with Intermediate-Mass Stars: Results of the SEEDS YSO Survey

Science.gov (United States)

Grady, C.; Fukagawa, M.; Maruta, Y.; Ohta, Y.; Wisniewski, J.; Hashimoto, J.; Okamoto, Y.; Momose, M.; Currie, T.; McElwain, M.;

Observations of Intermediate-mass Black Holes and Ultra-Luminous X-ray sources

Science.gov (United States)

Colbert, E. J. M.

2003-12-01

I will review various observations that suggest that intermediate-mass black holes (IMBHs) with masses ˜102-104 M⊙ exist in our Universe. I will also discuss some of the limitations of these observations. HST Observations of excess dark mass in globular cluster cores suggest IMBHs may be responsible, and some mass estimates from lensing experiments are nearly in the IMBH range. The intriguing Ultra-Luminous X-ray sources (ULXs, or IXOs) are off-nuclear X-ray point sources with X-ray luminosities LX ≳ 1039 erg s-1. ULXs are typically rare (1 in every 5 galaxies), and the nature of their ultra-luminous emission is currently debated. I will discuss the evidence for IMBHs in some ULXs, and briefly outline some phenomenology. Finally, I will discuss future observations that can be made to search for IMBHs.

THE CONTRIBUTIONS OF INTERACTIVE BINARY STARS TO DOUBLE MAIN-SEQUENCE TURNOFFS AND DUAL RED CLUMP OF INTERMEDIATE-AGE STAR CLUSTERS

International Nuclear Information System (INIS)

Yang Wuming; Bi Shaolan; Tian Zhijia; Li Tanda; Liu Kang; Meng Xiangcun

2011-01-01

Double or extended main-sequence turnoffs (DMSTOs) and dual red clump (RC) were observed in intermediate-age clusters, such as in NGC 1846 and 419. The DMSTOs are interpreted as that the cluster has two distinct stellar populations with differences in age of about 200-300 Myr but with the same metallicity. The dual RC is interpreted as a result of a prolonged star formation. Using a stellar population-synthesis method, we calculated the evolution of a binary-star stellar population. We found that binary interactions and merging can reproduce the dual RC in the color-magnitude diagrams of an intermediate-age cluster, whereas in actuality only a single population exists. Moreover, the binary interactions can lead to an extended main-sequence turnoff (MSTO) rather than DMSTOs. However, the rest of the main sequence, subgiant branch, and first giant branch are hardly spread by the binary interactions. Part of the observed dual RC and extended MSTO may be the results of binary interactions and mergers.

Symplectic no-core shell-model approach to intermediate-mass nuclei

Science.gov (United States)

Tobin, G. K.; Ferriss, M. C.; Launey, K. D.; Dytrych, T.; Draayer, J. P.; Dreyfuss, A. C.; Bahri, C.

2014-03-01

We present a microscopic description of nuclei in the intermediate-mass region, including the proximity to the proton drip line, based on a no-core shell model with a schematic many-nucleon long-range interaction with no parameter adjustments. The outcome confirms the essential role played by the symplectic symmetry to inform the interaction and the winnowing of shell-model spaces. We show that it is imperative that model spaces be expanded well beyond the current limits up through 15 major shells to accommodate particle excitations, which appear critical to highly deformed spatial structures and the convergence of associated observables.

Organophosphate-induced intermediate syndrome: aetiology and relationships with myopathy.

Science.gov (United States)

Karalliedde, Lakshman; Baker, David; Marrs, Timothy C

2006-01-01

The intermediate syndrome (IMS) following organophosphorus (OP) insecticide poisoning was first described in the mid-1980s. The syndrome described comprised characteristic symptoms and signs occurring after apparent recovery from the acute cholinergic syndrome. As the syndrome occurred after the acute cholinergic syndrome but before organophosphate-induced delayed polyneuropathy, the syndrome was called 'intermediate syndrome'. The IMS occurs in approximately 20% of patients following oral exposure to OP pesticides, with no clear association between the particular OP pesticide involved and the development of the syndrome. It usually becomes established 2-4 days after exposure when the symptoms and signs of the acute cholinergic syndrome (e.g. muscle fasciculations, muscarinic signs) are no longer obvious. The characteristic features of the IMS are weakness of the muscles of respiration (diaphragm, intercostal muscles and accessory muscles including neck muscles) and of proximal limb muscles. Accompanying features often include weakness of muscles innervated by some cranial nerves. It is now emerging that the degree and extent of muscle weakness may vary following the onset of the IMS. Thus, some patients may only have weakness of neck muscles whilst others may have weakness of neck muscles and proximal limb muscles. These patients may not require ventilatory care but close observation and monitoring of respiratory function is mandatory. Management is essentially that of rapidly developing respiratory distress and respiratory failure. Delays in instituting ventilatory care will result in death. Initiation of ventilatory care and maintenance of ventilatory care often requires minimal doses of non-depolarising muscle relaxants. The use of depolarising muscle relaxants such as suxamethonium is contraindicated in OP poisoning. The duration of ventilatory care required by patients may differ considerably and it is usual for patients to need ventilatory support for 7

Theoretical predictor for candidate structure assignment from IMS data of biomolecule-related conformational space.

Science.gov (United States)

Schenk, Emily R; Nau, Frederic; Fernandez-Lima, Francisco

2015-06-01

The ability to correlate experimental ion mobility data with candidate structures from theoretical modeling provides a powerful analytical and structural tool for the characterization of biomolecules. In the present paper, a theoretical workflow is described to generate and assign candidate structures for experimental trapped ion mobility and H/D exchange (HDX-TIMS-MS) data following molecular dynamics simulations and statistical filtering. The applicability of the theoretical predictor is illustrated for a peptide and protein example with multiple conformations and kinetic intermediates. The described methodology yields a low computational cost and a simple workflow by incorporating statistical filtering and molecular dynamics simulations. The workflow can be adapted to different IMS scenarios and CCS calculators for a more accurate description of the IMS experimental conditions. For the case of the HDX-TIMS-MS experiments, molecular dynamics in the "TIMS box" accounts for a better sampling of the molecular intermediates and local energy minima.

The First APOKASC Catalog of Kepler Dwarf and Subgiant Stars

Science.gov (United States)

Serenelli, Aldo; Johnson, Jennifer; Huber, Daniel; Pinsonneault, Marc; Ball, Warrick H.; Tayar, Jamie; Silva Aguirre, Victor; Basu, Sarbani; Troup, Nicholas; Hekker, Saskia; Kallinger, Thomas; Stello, Dennis; Davies, Guy R.; Lund, Mikkel N.; Mathur, Savita; Mosser, Benoit; Stassun, Keivan G.; Chaplin, William J.; Elsworth, Yvonne; García, Rafael A.; Handberg, Rasmus; Holtzman, Jon; Hearty, Fred; García-Hernández, D. A.; Gaulme, Patrick; Zamora, Olga

2017-12-01

We present the first APOKASC catalog of spectroscopic and asteroseismic data for dwarfs and subgiants. Asteroseismic data for our sample of 415 objects have been obtained by the Kepler mission in short (58.5 s) cadence, and light curves span from 30 up to more than 1000 days. The spectroscopic parameters are based on spectra taken as part of the Apache Point Observatory Galactic Evolution Experiment and correspond to Data Release 13 of the Sloan Digital Sky Survey. We analyze our data using two independent {T}{eff} scales, the spectroscopic values from DR13 and those derived from SDSS griz photometry. We use the differences in our results arising from these choices as a test of systematic temperature uncertainties and find that they can lead to significant differences in the derived stellar properties. Determinations of surface gravity ({log}g), mean density ( ), radius (R), mass (M), and age (τ) for the whole sample have been carried out by means of (stellar) grid-based modeling. We have thoroughly assessed random and systematic error sources in the spectroscopic and asteroseismic data, as well as in the grid-based modeling determination of the stellar quantities provided in the catalog. We provide stellar properties determined for each of the two {T}{eff} scales. The median combined (random and systematic) uncertainties are 2% (0.01 dex; {log}g), 3.4% ( ), 2.6% (R), 5.1% (M), and 19% (τ) for the photometric {T}{eff} scale and 2% ({log}g), 3.5% ( ), 2.7% (R), 6.3% (M), and 23% (τ) for the spectroscopic scale. We present comparisons with stellar quantities in the asteroseismic catalog by Chaplin et al. that highlight the importance of having metallicity measurements for determining stellar parameters accurately. Finally, we compare our results with those coming from a variety of sources, including stellar radii determined from TGAS parallaxes and asteroseismic analyses based on individual frequencies. We find a very good agreement for all inferred quantities

Coronal mass ejection shock fronts containing the two types of intermediate shocks

International Nuclear Information System (INIS)

Steinolfson, R.S.; Hundhausen, A.J.

1990-01-01

Numerical solutions of the time-dependent, magnetohydrodynamic (MHD) equations in two dimensions are used to demonstrate the formation of both types of intermediate shocks in a single shock front for physical conditions that are an idealization of those expected to occur in some observed coronal mass ejections. The key to producing such a shock configuration in the simulations is the use of an initial atmosphere containing a magnetic field representative of that in a coronal streamer with open field lines overlying a region of closed field lines. Previous attempts using just open field lines (perpendicular to the surface) produced shock configurations containing just one of the two intermediate shock types. A schematic of such a shock front containing both intermediate shock types has been constructed previously based solely on the known properties of MHD shocks from the Rankine-Hugoniot equations and specific requirements placed on the shock solution at points along the front where the shock normal and upstream magnetic field are aligned. The shock front also contains, at various locations along the front, a hydrodynamic (nonmagnetic) shock, a switch-on shock, and a fast shock in addition to the intermediate shocks. This particular configuration occurs when the shock front speed exceeds the upstream (preshock) intermediate wave speed but is less than a critical speed defined in the paper (equation 1) along at least some portion of the shock front. A distinctive feature of the front is that it is concave upward (away from the surface) near the region where the field in the preshock plasma is normal to the front of near the central portion of the shock front

Search for intermediate mass black hole binaries in the first observing run of Advanced LIGO

OpenAIRE

Abbott, B. P.; Abbott, R.; Adhikari, R. X.; Ananyeva, A.; Anderson, S. B.; Appert, S.; Arai, K.; Araya, M. C.; Barayoga, J. C.; Barish, B. C.; Berger, B. K.; Billingsley, G.; Blackburn, J. K.; Bork, R.; Brooks, A. F.

2017-01-01

During their first observational run, the two Advanced LIGO detectors attained an unprecedented sensitivity, resulting in the first direct detections of gravitational-wave signals produced by stellar-mass binary black hole systems. This paper reports on an all-sky search for gravitational waves (GWs) from merging intermediate mass black hole binaries (IMBHBs). The combined results from two independent search techniques were used in this study: the first employs a matched-filter algorithm that...

Interpretation of the gap on the subgiant branch of several globular clusters

Energy Technology Data Exchange (ETDEWEB)

Armandroff, T.E.; Demarque, P.

1984-10-01

Four globular clusters whose color-magnitude diagrams show a gap on the subgiant branch are discussed. Standard stellar evolution theory does not predict the existence of a rapid phase of evolution at this point during a star's lifetime. A mechanism is outlined where this rapid evolutionary phase is attributed to the hydrogen-burning shell passing through a discontinuity in chemical composition. This discontinuity is set up by an ad-hoc mixing process. The plausibility of this mixing is discussed. The thermal-profile history of the star constrains this mixing process to occur only during a short period following the main-sequence turnoff. Evolutionary tracks constructed using this scheme result in a gap crossing time a factor of two smaller than the standard model and almost identical evolution outside the gap. While this is suggestive, it cannot completely explain the gap. Another possibility, that the gap is caused by a rapid change in atmospheric structure, is investigated by varying the mixing length in the convection zone. Tracks constructed in this manner are not consistent with the observed gaps.

Quick scan IMS vendors

NARCIS (Netherlands)

Norp, A.H.J.; Pals, H.; Walraven, F.A.

2007-01-01

IMS is gaining momentum in the market. First operators are deploying IMS, while other operators are considering buying IMS. Operators have two approaches for introducing IMS and building an IMS eco-system: • Buying IMS from a large vendor or system integrator. Vendors like Alcatel-Lucent, Ericsson

Ion-neutral potential models in atmospheric pressure ion mobility time-of-flight mass spectrometry IM(tof)MS.

Science.gov (United States)

Steiner, Wes E; English, William A; Hill, Herbert H

2006-02-09

The ion mobilities and their respective masses of several classes of amines (primary, secondary, and tertiary) were measured by electrospray ionization atmospheric pressure ion mobility time-of-flight mass spectrometry IM(tof)MS. The experimental data obtained were comparatively analyzed by the one-temperature kinetic theory of Chapman-Enskog. Several theoretical models were used to estimate the collision cross-sections; they include the rigid-sphere, polarization-limit, 12-6-4, and 12-4 potential models. These models were investigated to represent the interaction potentials contained within the collision integral that occurs between the polyatomic ions and the neutral drift gas molecules. The effectiveness of these collision cross-section models on predicting the mobility of these amine ions was explored. Moreover, the effects of drift gas selectivity on the reduced-mass term and in the collision cross-section term was examined. Use of a series of drift gases, namely, helium, neon, argon, nitrogen, and carbon dioxide, made it possible to distinguish between mass effects and polarizability effects. It was found that the modified 12-4 potential that compensates for the center of charge not being at the same location as the centers of mass showed improved agreement over the other collision cross-section models with respect to experimental data.

Theoretical study of intermediate-mass fragments in proton-nucleus reactions at 200 MeV

Energy Technology Data Exchange (ETDEWEB)

Sabra, Mohammad S. [NASA Marshall Space Flight Center, USRA Space Science Department, Huntsville, AL (United States)

2017-03-15

We have analyzed energy spectra, angular distributions, and mass and charge distributions of intermediate-mass fragments (IMFs) from the interaction of {sup 27}Al, {sup 59}Co, and {sup 197}Au with 200 MeV protons. Calculations within the modified statistical model with final-state interaction were performed using SAPTON code. Within the experimental uncertainty and constraint, SAPTON shows good agreement with the data, and suggests that the IMFs are produced after the intra-nuclear cascade stage, and during the surface coalescence, as well as the evaporation/fission stages. (orig.)

IMS Application Developer's Handbook Creating and Deploying Innovative IMS Applications

CERN Document Server

Noldus, Rogier; Mulligan, Catherine; Fikouras, Ioannis; Ryde, Anders; Stille, Mats

2011-01-01

IMS Application Developer Handbook will give a hands-on view of exactly what needs to be done by IMS application developers to write an application and take it "live" on an operator's network. It will offer practical guidance on building innovative applications using the features and capabilities of the IMS network, show how the rapidly changing development environment is impacting on the business models employed in the industry and how existing network solutions can be moved towards IMS. The book will also elaborate on how IMS applies basic VoIP principles and techniques to realise a true mul

Necessity of intermediate mass scales in grand unified theories with spontaneously broken CP invariance

International Nuclear Information System (INIS)

Senjanovic, G.

1982-07-01

It is demonstrated that the spontaneous breakdown of CP invariance in grand unified theories requires the presence of intermediate mass scales. The simplest realization is provided by weakly broken left-right symmetry in the context of SU(2)sub(L) x SU(2)sub(R) x U(1)sub(B-L) model embedded in grand unified theories. (author)

[Imaging Mass Spectrometry in Histopathologic Analysis].

Science.gov (United States)

Yamazaki, Fumiyoshi; Seto, Mitsutoshi

2015-04-01

Matrix-assisted laser desorption/ionization (MALDI)-imaging mass spectrometry (IMS) enables visualization of the distribution of a range of biomolecules by integrating biochemical information from mass spectrometry with positional information from microscopy. IMS identifies a target molecule. In addition, IMS enables global analysis of biomolecules containing unknown molecules by detecting the ratio of the molecular weight to electric charge without any target, which makes it possible to identify novel molecules. IMS generates data on the distribution of lipids and small molecules in tissues, which is difficult to visualize with either conventional counter-staining or immunohistochemistry. In this review, we firstly introduce the principle of imaging mass spectrometry and recent advances in the sample preparation method. Secondly, we present findings regarding biological samples, especially pathological ones. Finally, we discuss the limitations and problems of the IMS technique and clinical application, such as in drug development.

I'm a Map, I'm a Green Tree

Science.gov (United States)

Anderson, Daniel

2010-01-01

I'm talking about the ways we represent ourselves and our world. I've put some thoughts on the topic together here--a gathering that enacts new media creating and takes up conceptual layers like metaphors, models, and composing. The primary sources are videos from the Get a Mac campaign, aka I'm a Mac; I'm a PC ads. Posthuman concepts blending…

Intermediate-mass Higgs boson and isosinglet neutral heavy lepton signals at hadron supercolliders

International Nuclear Information System (INIS)

Bhattacharya, G.

1992-01-01

The signals for the Standard Model intermediate-mass Higgs boson and isosinglet neutral heavy leptons at the forthcoming hadron supercolliders-the Superconducting Super Collider (SSC) and the CERN Large Hadron Collider (LHC), are studied. The author studies inclusive production of the Standard Model Higgs boson in the intermediate-mass region (M W approx-lt m H approx-lt 2M Z ) and its subsequent decay into two on- or off-shell W bosons that decay leptonically. Backgrounds from continuum W pair production and top quark pair production with semileptonic decays are investigated. The author concludes the Higgs boson signal may be observed via the decay H → W*W* → (ell bar v ell ) (bar ell' v' ell ) at the SSC for 145 GeV H approx-lt 2M Z and at the LHC for 150 GeV H approx-lt 2M Z if m t > 150 GeV. The author analyzes the search and discovery potential of isosinglet neutral heavy leptons (NHLs) produced via real or virtual W decay at pp supercolliders. The author considers the signal resulting from the leptonic decay of the NHL, and the two major backgrounds-continuum WZ, Wγ production and t bar tj production, where j is a hadronic jet. The decay patterns of NHL depend on its mass M N , and different search strategies are needed for the two mass regions M N W and M N > M Z . The author finds for m t ≥ 150 (200) GeV the signal is observable for M N ≤ 60 (70) GeV in the mass-region M N W , and up to M N ≅ 110 GeV for M N > M W , at both SSC and LHC. It is shown the non-observance of the signal (with a 4σ statistical significance) in the region M N W could put upper limits on the NHL coupling constants that would be an improvement over the limits obtainable from the CERN Large Electron Positron Collider (LEP I)

The dwarfs beyond: The stellar-to-halo mass relation for a new sample of intermediate redshift low-mass galaxies

Energy Technology Data Exchange (ETDEWEB)

Miller, Sarah H.; Ellis, Richard S.; Newman, Andrew B. [California Institute of Technology, 1200 E. California Blvd, Pasadena, CA 91125 (United States); Benson, Andrew, E-mail: smiller@astro.caltech.edu [Carnegie Observatories, 813 Santa Barbara St, Pasadena, CA 91101 (United States)

2014-02-20

A number of recent challenges to the standard ΛCDM paradigm relate to discrepancies that arise in comparing the abundance and kinematics of local dwarf galaxies with the predictions of numerical simulations. Such arguments rely heavily on the assumption that the Local Volume's dwarf and satellite galaxies form a representative distribution in terms of their stellar-to-halo mass ratios. To address this question, we present new, deep spectroscopy using DEIMOS on Keck for 82 low-mass (10{sup 7}-10{sup 9} M {sub ☉}), star-forming galaxies at intermediate redshift (0.2 < z < 1). For 50% of these we are able to determine resolved rotation curves using nebular emission lines and thereby construct the stellar mass Tully-Fisher relation to masses as low as 10{sup 7} M {sub ☉}. Using scaling relations determined from weak lensing data, we convert this to a stellar-to-halo mass relation for comparison with abundance matching predictions. We find a discrepancy between our observations and the predictions from abundance matching in the sense that we observe 3-12 times more stellar mass at a given halo mass. We suggest possible reasons for this discrepancy, as well as improved tests for the future.

Evolution, Nucleosynthesis, and Yields of AGB Stars at Different Metallicities. III. Intermediate-mass Models, Revised Low-mass Models, and the ph-FRUITY Interface

Science.gov (United States)

Cristallo, S.; Straniero, O.; Piersanti, L.; Gobrecht, D.

2015-08-01

We present a new set of models for intermediate-mass asymptotic giant branch (AGB) stars (4.0, 5.0, and 6.0 M⊙) at different metallicities (-2.15 ≤ [Fe/H] ≤ +0.15). This set integrates the existing models for low-mass AGB stars (1.3 ≤ M/M⊙ ≤ 3.0) already included in the FRUITY database. We describe the physical and chemical evolution of the computed models from the main sequence up to the end of the AGB phase. Due to less efficient third dredge up episodes, models with large core masses show modest surface enhancements. This effect is due to the fact that the interpulse phases are short and, therefore, thermal pulses (TPs) are weak. Moreover, the high temperature at the base of the convective envelope prevents it from deeply penetrating the underlying radiative layers. Depending on the initial stellar mass, the heavy element nucleosynthesis is dominated by different neutron sources. In particular, the s-process distributions of the more massive models are dominated by the 22Ne(α,n)25Mg reaction, which is efficiently activated during TPs. At low metallicities, our models undergo hot bottom burning and hot third dredge up. We compare our theoretical final core masses to available white dwarf observations. Moreover, we quantify the influence intermediate-mass models have on the carbon star luminosity function. Finally, we present the upgrade of the FRUITY web interface, which now also includes the physical quantities of the TP-AGB phase for all of the models included in the database (ph-FRUITY).

Radial Velocities of Subgiant Stars and New Astrophysical Insights into RV Jitter

Science.gov (United States)

Luhn, Jacob; Bastien, Fabienne; Wright, Jason T.

2018-01-01

For nearly 20 years, the California Planet Search (CPS) has simultaneously monitored precise radial velocities and chromospheric activity levels of stars from Keck observatory to search for exoplanets. This sample provides a useful set of stars to better determine the dependence of RV jitter on flicker (which traces surface gravity) first shown in Bastien et al. (2014). We expand upon this initial work by examining a much larger sample of stars covering a much wider range of stellar parameters (effective temperature, surface gravity, and activity, among others). For more than 600 stars, there are enough RV measurements to distinguish this astrophysical jitter from accelerations due to orbital companions. To properly isolate RV jitter from these effects, we must first remove the RV signal due to these companions, including several previously unannounced giant planets around subgiant stars. We highlight some new results from our analysis of the CPS data. A more thorough understanding of the various sources of RV jitter and the underlying stellar phenomena that drive these intrinsic RV variations will enable more precise jitter estimates for RV follow-up targets such as those from K2 or the upcoming TESS mission.

An interpretation of the gap on the subgiant branch of several globular clusters

International Nuclear Information System (INIS)

Armandroff, T.E.; Demarque, P.

1984-01-01

Four globular clusters whose color-magnitude diagrams show a gap on the subgiant branch are discussed. Standard stellar evolution theory does not predict the existence of a rapid phase of evolution at this point during a star's lifetime. A mechanism is outlined where this rapid evolutionary phase is attributed to the hydrogen-burning shell passing through a discontinuity in chemical composition. This discontinuity is set up by an ad-hoc mixing process. The plausibility of this mixing is discussed. The thermal-profile history of the star constrains this mixing process to occur only during a short period following the main-sequence turnoff. Evolutionary tracks constructed using this scheme result in a gap crossing time a factor of two smaller than the standard model and almost identical evolution outside the gap. While this is suggestive, it cannot completely explain the gap. Another possibility, that the gap is caused by a rapid change in atmospheric structure, is investigated by varying the mixing length in the convection zone. Tracks constructed in this manner are not consistent with the observed gaps. (orig.)

RETIRED A STARS AND THEIR COMPANIONS. VI. A PAIR OF INTERACTING EXOPLANET PAIRS AROUND THE SUBGIANTS 24 SEXTANIS AND HD 200964

International Nuclear Information System (INIS)

Johnson, John Asher; Payne, Matthew; Ford, Eric B.; Howard, Andrew W.; Marcy, Geoffrey W.; Clubb, Kelsey I.; Bowler, Brendan P.; Henry, Gregory W.; Fischer, Debra A.; Brewer, John M.; Schwab, Christian; Reffert, Sabine; Lowe, Thomas B.

2011-01-01

We report radial velocity (RV) measurements of the G-type subgiants 24 Sextanis (= HD 90043) and HD 200964. Both are massive, evolved stars that exhibit periodic variations due to the presence of a pair of Jovian planets. Photometric monitoring with the T12 0.80 m APT at Fairborn Observatory demonstrates both stars to be constant in brightness to ≤0.002 mag, thus strengthening the planetary interpretation of the RV variations. Based on our dynamical analysis of the RV time series, 24 Sex b, c have orbital periods of 452.8 days and 883.0 days, corresponding to semimajor axes 1.333 AU and 2.08 AU, and minimum masses 1.99 M Jup and 0.86 M Jup , assuming a stellar mass M * = 1.54 M sun . HD 200964 b, c have orbital periods of 613.8 days and 825.0 days, corresponding to semimajor axes 1.601 AU and 1.95 AU, and minimum masses 1.99 M Jup and 0.90 M Jup , assuming M * = 1.44 M sun . We also carry out dynamical simulations to properly account for gravitational interactions between the planets. Most, if not all, of the dynamically stable solutions include crossing orbits, suggesting that each system is locked in a mean-motion resonance that prevents close encounters and provides long-term stability. The planets in the 24 Sex system likely have a period ratio near 2:1, while the HD 200964 system is even more tightly packed with a period ratio close to 4:3. However, we caution that further RV observations and more detailed dynamical modeling will be required to provide definitive and unique orbital solutions for both cases, and to determine whether the two systems are truly resonant.

iMS2Flux – a high–throughput processing tool for stable isotope labeled mass spectrometric data used for metabolic flux analysis

Directory of Open Access Journals (Sweden)

Poskar C Hart

2012-11-01

Full Text Available Abstract Background Metabolic flux analysis has become an established method in systems biology and functional genomics. The most common approach for determining intracellular metabolic fluxes is to utilize mass spectrometry in combination with stable isotope labeling experiments. However, before the mass spectrometric data can be used it has to be corrected for biases caused by naturally occurring stable isotopes, by the analytical technique(s employed, or by the biological sample itself. Finally the MS data and the labeling information it contains have to be assembled into a data format usable by flux analysis software (of which several dedicated packages exist. Currently the processing of mass spectrometric data is time-consuming and error-prone requiring peak by peak cut-and-paste analysis and manual curation. In order to facilitate high-throughput metabolic flux analysis, the automation of multiple steps in the analytical workflow is necessary. Results Here we describe iMS2Flux, software developed to automate, standardize and connect the data flow between mass spectrometric measurements and flux analysis programs. This tool streamlines the transfer of data from extraction via correction tools to 13C-Flux software by processing MS data from stable isotope labeling experiments. It allows the correction of large and heterogeneous MS datasets for the presence of naturally occurring stable isotopes, initial biomass and several mass spectrometry effects. Before and after data correction, several checks can be performed to ensure accurate data. The corrected data may be returned in a variety of formats including those used by metabolic flux analysis software such as 13CFLUX, OpenFLUX and 13CFLUX2. Conclusion iMS2Flux is a versatile, easy to use tool for the automated processing of mass spectrometric data containing isotope labeling information. It represents the core framework for a standardized workflow and data processing. Due to its flexibility

Impact of intermediate mammography assessment on the likelihood of false-positive results in breast cancer screening programmes

International Nuclear Information System (INIS)

Ascunce, Nieves; Ederra, Maria; Delfrade, Josu; Erdozain, Nieves; Baroja, Araceli; Zubizarreta, Raquel; Salas, Dolores; Castells, Xavier

2012-01-01

Breast cancer screening is offered to 100% of the target population in Spain and intermediate mammograms (IMs) are sometimes indicated. This study was aimed at analysing the frequency of IMs, the factors determining their recommendation, and their impact on the risk of false-positive results and the detection rate. Data from 3,471,307 mammograms from Spanish breast cancer screening programmes were included. 3.36% of the mammograms were IMs. The factors associated with the use of IMs were age, initial screening, previous invasive tests, a familial history of breast cancer and use of hormone replacement therapy. In screening episodes with an IM, the probability of a false-positive result was 13.74% (95% CI: 13.43-14.05), almost double that in episodes without IMs (6.02%, 95% CI 5.99-6.05). In young women with previous invasive procedures, a familial history of breast cancer or hormone replacement therapy use who were undergoing their initial screen, this probability was lower when IMs were performed. IMs always increased the detection rate. The factors prompting IMs should be characterised so that radiologists can systematise their recommendations according to the presence of the factors maximising the benefits and minimising the adverse effects of this procedure. (orig.)

Impact of intermediate mammography assessment on the likelihood of false-positive results in breast cancer screening programmes

Energy Technology Data Exchange (ETDEWEB)

Ascunce, Nieves [Public Health Institute, CIBERESP, Navarra Breast Cancer Screening Programme, Pamplona (Spain); Instituto de Salud Publica, Navarra Breast Cancer Screening Programme, Pamplona (Spain); Ederra, Maria; Delfrade, Josu; Erdozain, Nieves [Public Health Institute, CIBERESP, Navarra Breast Cancer Screening Programme, Pamplona (Spain); Baroja, Araceli [Fundacion Rioja Salud, Logrono (Spain); Zubizarreta, Raquel [Public Health and Planning Directorate, Health Office, Galician Breast Cancer Screening Programme, Galicia (Spain); Salas, Dolores [General Directorate Public Health and Centre for Public Health Research (CSISP), Valencia (Spain); Castells, Xavier [Mar Teaching Hospital, CIBERESP, Department of Clinical Epidemiology, Barcelona (Spain)

2012-02-15

Breast cancer screening is offered to 100% of the target population in Spain and intermediate mammograms (IMs) are sometimes indicated. This study was aimed at analysing the frequency of IMs, the factors determining their recommendation, and their impact on the risk of false-positive results and the detection rate. Data from 3,471,307 mammograms from Spanish breast cancer screening programmes were included. 3.36% of the mammograms were IMs. The factors associated with the use of IMs were age, initial screening, previous invasive tests, a familial history of breast cancer and use of hormone replacement therapy. In screening episodes with an IM, the probability of a false-positive result was 13.74% (95% CI: 13.43-14.05), almost double that in episodes without IMs (6.02%, 95% CI 5.99-6.05). In young women with previous invasive procedures, a familial history of breast cancer or hormone replacement therapy use who were undergoing their initial screen, this probability was lower when IMs were performed. IMs always increased the detection rate. The factors prompting IMs should be characterised so that radiologists can systematise their recommendations according to the presence of the factors maximising the benefits and minimising the adverse effects of this procedure. (orig.)

Medical Advice for Sick-reported Students (MASS) in intermediate vocational education schools: design of a controlled before-and-after study.

Science.gov (United States)

Van der Vlis, Madelon K; Lugtenberg, Marjolein; Vanneste, Yvonne T M; Berends, Wenda; Mulder, Wico; Bannink, Rienke; Van Grieken, Amy; Raat, Hein; de Kroon, Marlou L A

2017-06-29

School absenteeism, including medical absenteeism, is associated with early school dropout and may result in physical, mental, social and work-related problems in later life. Especially at intermediate vocational education schools, high rates of medical absenteeism are found. In 2012 the Dutch intervention 'Medical Advice for Sick-reported Students' (MASS), previously developed for pre-vocational secondary education, was adjusted for intermediate vocational education schools. The aim of the study outlined in this paper is to evaluate the effectiveness of the MASS intervention at intermediate vocational education schools in terms of reducing students' medical absenteeism and early dropping out of school. Additionally, the extent to which biopsychosocial and other factors moderate the effectiveness of the intervention will be assessed. A controlled before-and-after study will be conducted within Intermediate Vocational Education schools. Schools are allocated to be an intervention or control school based on whether the schools have implemented the MASS intervention (intervention schools) or not (control schools). Intervention schools apply the MASS intervention consisting of active support for students with medical absenteeism provided by the school including a consultation with the Youth Health Care (YHC) professional if needed. Control schools provide care as usual. Data will be collected by questionnaires among students in both groups meeting the criteria for extensive medical absenteeism (i.e. 'reported sick four times in 12 school weeks or for more than six consecutive school days' at baseline and at 6 months follow-up). Additionally, in the intervention group a questionnaire is completed after each consultation with a YHC professional, by both the student and the YHC professional. Primary outcome measures are duration and cumulative incidence of absenteeism and academic performances. Secondary outcome measures are biopsychosocial outcomes of the students. It

Ab initio results for intermediate-mass, open-shell nuclei

Science.gov (United States)

Baker, Robert B.; Dytrych, Tomas; Launey, Kristina D.; Draayer, Jerry P.

2017-01-01

A theoretical understanding of nuclei in the intermediate-mass region is vital to astrophysical models, especially for nucleosynthesis. Here, we employ the ab initio symmetry-adapted no-core shell model (SA-NCSM) in an effort to push first-principle calculations across the sd-shell region. The ab initio SA-NCSM's advantages come from its ability to control the growth of model spaces by including only physically relevant subspaces, which allows us to explore ultra-large model spaces beyond the reach of other methods. We report on calculations for 19Ne and 20Ne up through 13 harmonic oscillator shells using realistic interactions and discuss the underlying structure as well as implications for various astrophysical reactions. This work was supported by the U.S. NSF (OCI-0904874 and ACI -1516338) and the U.S. DOE (DE-SC0005248), and also benefitted from the Blue Waters sustained-petascale computing project and high performance computing resources provided by LSU.

Organisationsprobleme im Ökomarketing

OpenAIRE

Dienel, Wolfram

2000-01-01

Organisationsprobleme im Ökomarketing - eine transaktionskostentheoretische Analyse im Absatzkanal konventioneller Lebensmittelhandel Die im Vergleich zum großen Nachfragepotential zögerliche Entwicklung des Ökomarkts in Deutschland ist auf Organisationsprobleme zurückzuführen. Die Organisationsprobleme behindern insbesondere die großskalige Ökomarkterschließung über die konventionellen Supermarktketten, erschweren aber auch die Effizienzsteigerung im kleiner strukturierten alternativen N...

A luminous X-ray outburst from an intermediate-mass black hole in an off-centre star cluster

Science.gov (United States)

Lin, Dacheng; Strader, Jay; Carrasco, Eleazar R.; Page, Dany; Romanowsky, Aaron J.; Homan, Jeroen; Irwin, Jimmy A.; Remillard, Ronald A.; Godet, Olivier; Webb, Natalie A.; Baumgardt, Holger; Wijnands, Rudy; Barret, Didier; Duc, Pierre-Alain; Brodie, Jean P.; Gwyn, Stephen D. J.

2018-06-01

A unique signature for the presence of massive black holes in very dense stellar regions is occasional giant-amplitude outbursts of multi-wavelength radiation from tidal disruption and subsequent accretion of stars that make a close approach to the black holes1. Previous strong tidal disruption event (TDE) candidates were all associated with the centres of largely isolated galaxies2-6. Here, we report the discovery of a luminous X-ray outburst from a massive star cluster at a projected distance of 12.5 kpc from the centre of a large lenticular galaxy. The luminosity peaked at 1043 erg s-1 and decayed systematically over 10 years, approximately following a trend that supports the identification of the event as a TDE. The X-ray spectra were all very soft, with emission confined to be ≲3.0 keV, and could be described with a standard thermal disk. The disk cooled significantly as the luminosity decreased—a key thermal-state signature often observed in accreting stellar-mass black holes. This thermal-state signature, coupled with very high luminosities, ultrasoft X-ray spectra and the characteristic power-law evolution of the light curve, provides strong evidence that the source contains an intermediate-mass black hole with a mass tens of thousand times that of the solar mass. This event demonstrates that one of the most effective means of detecting intermediate-mass black holes is through X-ray flares from TDEs in star clusters.

Thermal instabilities in low-mass subgiants?

International Nuclear Information System (INIS)

Von Rudloff, I.R.; Vandenberg, D.A.; Hartwick, F.D.A.

1988-01-01

The thermal stability of evolving stars in globular clusters has been examined in order to determine whether or not gaps and the observationally inferred deep mixing near the base of the red-giant branch can be explained in terms of an instability of the hydrogen-burning shell. The results of this investigation are that, in agreement with previous suggestions, the greatest potential for such an instability occurs just at the point where a star begins to ascend the giant branch - i.e., where gaps are seen in some systems - but, in contrast with earlier predictions, the standard models do not actually become unstable. However, from all indications, the stability is believed to be marginal, and it is suggested that rotation, which has now been observed in some globulars, may be the mechanism by which an instability is produced. 36 references

EVOLUTION, NUCLEOSYNTHESIS, AND YIELDS OF AGB STARS AT DIFFERENT METALLICITIES. III. INTERMEDIATE-MASS MODELS, REVISED LOW-MASS MODELS, AND THE pH-FRUITY INTERFACE

Energy Technology Data Exchange (ETDEWEB)

Cristallo, S.; Straniero, O.; Piersanti, L.; Gobrecht, D. [INAF-Osservatorio Astronomico di Collurania, I-64100 Teramo (Italy)

2015-08-15

We present a new set of models for intermediate-mass asymptotic giant branch (AGB) stars (4.0, 5.0, and 6.0 M{sub ⊙}) at different metallicities (−2.15 ≤ [Fe/H] ≤ +0.15). This set integrates the existing models for low-mass AGB stars (1.3 ≤ M/M{sub ⊙} ≤ 3.0) already included in the FRUITY database. We describe the physical and chemical evolution of the computed models from the main sequence up to the end of the AGB phase. Due to less efficient third dredge up episodes, models with large core masses show modest surface enhancements. This effect is due to the fact that the interpulse phases are short and, therefore, thermal pulses (TPs) are weak. Moreover, the high temperature at the base of the convective envelope prevents it from deeply penetrating the underlying radiative layers. Depending on the initial stellar mass, the heavy element nucleosynthesis is dominated by different neutron sources. In particular, the s-process distributions of the more massive models are dominated by the {sup 22}Ne(α,n){sup 25}Mg reaction, which is efficiently activated during TPs. At low metallicities, our models undergo hot bottom burning and hot third dredge up. We compare our theoretical final core masses to available white dwarf observations. Moreover, we quantify the influence intermediate-mass models have on the carbon star luminosity function. Finally, we present the upgrade of the FRUITY web interface, which now also includes the physical quantities of the TP-AGB phase for all of the models included in the database (ph-FRUITY)

Liquid-vapor phase transition, collective flow and entropy determination from future measurements of intermediate mass fragments

International Nuclear Information System (INIS)

Coffin, J.P.

1991-01-01

Some global variables reflecting the highly collective character of nuclear matter produced in relativistic heavy-ion collisions are briefly reviewed on the basis of presently available experimental results and of Quantum Statistical Model and Quantum Molecular Dynamic Model predictions relative to intermediate mass fragments. Possible future measurements are suggested. (author) 27 refs., 8 figs

Correlations of intermediate mass fragments from Fe+Ta, Au, and Th collisions

International Nuclear Information System (INIS)

Sangster, T.C.; Begemann-Blaich, M.; Blaich, T.; Britt, H.C.; Hansen, L.F.; Namboodiri, M.N.; Peilert, G.

1995-01-01

Charge, velocity, and angular correlations between intermediate mass fragments (IMF) are presented for 50 and 100 MeV/nucleon Fe bombardments of Ta, Au, and Th targets. Correlation functions generated as a function of the relative velocity and the opening angle between two IMF's are qualitatively independent of the projectile energy and target mass and show a suppression at small relative velocities and opening angles due to the Coulomb repulsion between the fragments. The correlations are consistent with IMF's emitted primarily from a highly excited target residue following a rapid preequilibrium cascade. The correlation data are compared to model calculations using the event generator MENEKA and the quantum molecular dynamics (QMD) code with a statistical deexcitation of residual fragments utilizing the multifragmentation code SMM. All data are consistent with a simultaneous multifragmentation at a freeze-out density of 0.1--0.3 times normal nuclear matter density or a more sequential emission with time constant τ≤500 fm/c

Interferometric diameters of five evolved intermediate-mass planet-hosting stars measured with PAVO at the CHARA Array

Science.gov (United States)

White, T. R.; Huber, D.; Mann, A. W.; Casagrande, L.; Grunblatt, S. K.; Justesen, A. B.; Silva Aguirre, V.; Bedding, T. R.; Ireland, M. J.; Schaefer, G. H.; Tuthill, P. G.

2018-04-01

Debate over the planet occurrence rates around intermediate-mass stars has hinged on the accurate determination of masses of evolved stars, and has been exacerbated by a paucity of reliable, directly-measured fundamental properties for these stars. We present long-baseline optical interferometry of five evolved intermediate-mass (˜ 1.5 M⊙) planet-hosting stars using the PAVO beam combiner at the CHARA Array, which we combine with bolometric flux measurements and parallaxes to determine their radii and effective temperatures. We measured the radii and effective temperatures of 6 Lyncis (5.12±0.16 R⊙, 4949±58 K), 24 Sextantis (5.49±0.18 R⊙, 4908±65 K), κ Coronae Borealis (4.77±0.07 R⊙, 4870±47 K), HR 6817 (4.45±0.08 R⊙, 5013±59 K), and HR 8641 (4.91±0.12 R⊙, 4950±68 K). We find disagreements of typically 15 % in angular diameter and ˜ 200 K in temperature compared to interferometric measurements in the literature, yet good agreement with spectroscopic and photometric temperatures, concluding that the previous interferometric measurements may have been affected by systematic errors exceeding their formal uncertainties. Modelling based on BaSTI isochrones using various sets of asteroseismic, spectroscopic, and interferometric constraints tends to favour slightly (˜ 15 %) lower masses than generally reported in the literature.

Contaminant screening of wastewater with HPLC-IM-qTOF-MS and LC+LC-IM-qTOF-MS using a CCS database.

Science.gov (United States)

Stephan, Susanne; Hippler, Joerg; Köhler, Timo; Deeb, Ahmad A; Schmidt, Torsten C; Schmitz, Oliver J

2016-09-01

Non-target analysis has become an important tool in the field of water analysis since a broad variety of pollutants from different sources are released to the water cycle. For identification of compounds in such complex samples, liquid chromatography coupled to high resolution mass spectrometry are often used. The introduction of ion mobility spectrometry provides an additional separation dimension and allows determining collision cross sections (CCS) of the analytes as a further physicochemical constant supporting the identification. A CCS database with more than 500 standard substances including drug-like compounds and pesticides was used for CCS data base search in this work. A non-target analysis of a wastewater sample was initially performed with high performance liquid chromatography (HPLC) coupled to an ion mobility-quadrupole-time of flight mass spectrometer (IM-qTOF-MS). A database search including exact mass (±5 ppm) and CCS (±1 %) delivered 22 different compounds. Furthermore, the same sample was analyzed with a two-dimensional LC method, called LC+LC, developed in our group for the coupling to IM-qTOF-MS. This four dimensional separation platform revealed 53 different compounds, identified over exact mass and CCS, in the examined wastewater sample. It is demonstrated that the CCS database can also help to distinguish between isobaric structures exemplified for cyclophosphamide and ifosfamide. Graphical Abstract Scheme of sample analysis and database screening.

Characterizing Intermediate-Mass, Pre-Main-Sequence Stars via X-Ray Emision

Science.gov (United States)

Haze Nunez, Evan; Povich, Matthew Samuel; Binder, Breanna Arlene; Broos, Patrick; Townsley, Leisa K.

2018-01-01

The X-ray emission from intermediate-mass, pre-main-sequence stars (IMPS) can provide useful constraints on the ages of very young (${getting power from the gravitational contraction of the star. Main-sequence late-B and A-type stars are not expected to be strong X-ray emitters, because they lack the both strong winds of more massive stars and the magneto-coronal activity of lower-mass stars. There is, however, mounting evidence that IMPS are powerful intrinsic x-ray emitters during their convection-dominated early evolution, before the development and rapid growth of a radiation zone. We present our prime candidates for intrinsic, coronal X-ray emission from IMPS identified in the Chandra Carina Complex Project. The Carina massive star-forming complex is of special interest due to the wide variation of star formation stages within the region. Candidate IMPS were identified using infrared spectral energy distribution (SED) models. X-ray properties, including thermal plasma temperatures and absorption-corrected fluxes, were derived from XSPEC fits performed using absorption ($N_{H}$) constrained by the extinction values returned by the infrared SED fits. We find that IMPS have systematically higher X-ray luminosities compared to their lower-mass cousins, the TTauri stars.This work is supported by the National Science Foundation under grant CAREER-1454334 and by NASA through Chandra Award 18200040.

Medical Advice for Sick-reported Students (MASS in intermediate vocational education schools: design of a controlled before-and-after study

Directory of Open Access Journals (Sweden)

Madelon K Van der Vlis

2017-06-01

Full Text Available Abstract Background School absenteeism, including medical absenteeism, is associated with early school dropout and may result in physical, mental, social and work-related problems in later life. Especially at intermediate vocational education schools, high rates of medical absenteeism are found. In 2012 the Dutch intervention ‘Medical Advice for Sick-reported Students’ (MASS, previously developed for pre-vocational secondary education, was adjusted for intermediate vocational education schools. The aim of the study outlined in this paper is to evaluate the effectiveness of the MASS intervention at intermediate vocational education schools in terms of reducing students’ medical absenteeism and early dropping out of school. Additionally, the extent to which biopsychosocial and other factors moderate the effectiveness of the intervention will be assessed. Methods A controlled before-and-after study will be conducted within Intermediate Vocational Education schools. Schools are allocated to be an intervention or control school based on whether the schools have implemented the MASS intervention (intervention schools or not (control schools. Intervention schools apply the MASS intervention consisting of active support for students with medical absenteeism provided by the school including a consultation with the Youth Health Care (YHC professional if needed. Control schools provide care as usual. Data will be collected by questionnaires among students in both groups meeting the criteria for extensive medical absenteeism (i.e. ‘reported sick four times in 12 school weeks or for more than six consecutive school days’ at baseline and at 6 months follow-up. Additionally, in the intervention group a questionnaire is completed after each consultation with a YHC professional, by both the student and the YHC professional. Primary outcome measures are duration and cumulative incidence of absenteeism and academic performances. Secondary outcome

Limits on runaway growth of intermediate mass black holes from advanced LIGO

Science.gov (United States)

Kovetz, Ely D.; Cholis, Ilias; Kamionkowski, Marc; Silk, Joseph

2018-06-01

There is growing evidence that intermediate-mass black holes (IMBHs), defined here as having a mass in the range M =500 -105 M⊙ , are present in the dense centers of certain globular clusters (GCs). Gravitational waves from their mergers with other IMBHs or with stellar BHs in the cluster are mostly emitted in frequencies ≲10 Hz , which unfortunately is out of reach for current ground-based observatories such as advanced LIGO (aLIGO). Nevertheless, we show that aLIGO measurements can be used to efficiently probe one of the possible formation mechanisms of IMBHs in GCs, namely a runaway merger process of stellar seed BHs. In this case, aLIGO will be sensitive to the lower-mass rungs of the merger ladder, ranging from the seed BH mass to masses ≳50 - 300 M⊙ , where the background from standard mergers is expected to be very low. Assuming this generic IMBH formation scenario, we calculate the mass functions that correspond to the limiting cases of possible merger trees. Based on estimates for the number density of GCs and taking into account the instrumental sensitivity, we show that current observations do not effectively limit the occupation fraction focc of IMBHs formed by runaway mergers of stellar BHs in GCs. However, we find that if runaway mergers occur steadily throughout the lifetimes of GCs (as opposed to happening mainly early in their lifetimes), then a six-year run of aLIGO at design sensitivity will be able to probe down to focc≲3 % at a 99.9% confidence level, either finding evidence for this formation mechanism, or necessitating others if the fraction of GCs that harbor IMBHs is higher.

A comprehensive review on experimental and clinical findings in intermediate syndrome caused by organophosphate poisoning

Energy Technology Data Exchange (ETDEWEB)

Abdollahi, Mohammad, E-mail: mohammad.abdollahi@utoronto.ca; Karami-Mohajeri, Somayyeh

2012-02-01

Acute organophosphate (OP) intoxication is important because of its high morbidity and mortality and occurrence of muscular paralysis associated by inhibition of acetylcholinesterase (AChE) activity at the neuromuscular junction. Cholinergic crisis, intermediate syndrome (IMS), and OP-induced delayed neuropathy (OPIDN) are the evidences that can be observed in OP intoxication. The main cause of morbidity due to OP poisoning is IMS that occurs 24–96 h after poisoning. Mechanisms underlying the IMS are not fully known. Although the electrophysiological aspects of delayed neuropathy are best characterized, the IMS remain very little studied. The aim of this study was to revisit current knowledge related to OP and the IMS. For this purpose, a systematic review without date limitation was performed. A total of 599 relevant articles were found and reviewed. Data were categorized according to experimental and clinical studies. Occurrences of persistent AChE inhibition, electromyography changes, muscle cell injury, and oxidative stress are the most important pieces of evidence for involvement of IMS in OP toxicity. Delayed AChE inhibition, muscle necrosis, down regulation or desensitization of postsynaptic ACh receptors, failure of postsynaptic ACh release, and oxidative stress-related myopathy are involved in IMS. Toxicokinetic factors, such as a high lipid-solubility, duration of AChE inhibition and metabolite excretion, evolution of alterations on repetitive nerve stimulation (RNS), type and frequency of muscle lesions can estimate the probability of the IMS. Plasma AChE of less than 200 units is a predictor and the 30 Hz RNS decremental response could be a useful marker for the IMS.

A comprehensive review on experimental and clinical findings in intermediate syndrome caused by organophosphate poisoning

International Nuclear Information System (INIS)

Abdollahi, Mohammad; Karami-Mohajeri, Somayyeh

2012-01-01

Acute organophosphate (OP) intoxication is important because of its high morbidity and mortality and occurrence of muscular paralysis associated by inhibition of acetylcholinesterase (AChE) activity at the neuromuscular junction. Cholinergic crisis, intermediate syndrome (IMS), and OP-induced delayed neuropathy (OPIDN) are the evidences that can be observed in OP intoxication. The main cause of morbidity due to OP poisoning is IMS that occurs 24–96 h after poisoning. Mechanisms underlying the IMS are not fully known. Although the electrophysiological aspects of delayed neuropathy are best characterized, the IMS remain very little studied. The aim of this study was to revisit current knowledge related to OP and the IMS. For this purpose, a systematic review without date limitation was performed. A total of 599 relevant articles were found and reviewed. Data were categorized according to experimental and clinical studies. Occurrences of persistent AChE inhibition, electromyography changes, muscle cell injury, and oxidative stress are the most important pieces of evidence for involvement of IMS in OP toxicity. Delayed AChE inhibition, muscle necrosis, down regulation or desensitization of postsynaptic ACh receptors, failure of postsynaptic ACh release, and oxidative stress-related myopathy are involved in IMS. Toxicokinetic factors, such as a high lipid-solubility, duration of AChE inhibition and metabolite excretion, evolution of alterations on repetitive nerve stimulation (RNS), type and frequency of muscle lesions can estimate the probability of the IMS. Plasma AChE of less than 200 units is a predictor and the 30 Hz RNS decremental response could be a useful marker for the IMS.

EVIDENCE FOR AN INTERMEDIATE-MASS BLACK HOLE IN NGC 5408 X-1

International Nuclear Information System (INIS)

Strohmayer, Tod E.; Mushotzky, Richard F.

2009-01-01

We report the discovery with XMM-Newton of correlated spectral and timing behavior in the ultraluminous X-ray source (ULX) NGC 5408 X-1. An ∼100 ks pointing with XMM/Newton obtained in 2008 January reveals a strong 10 mHz quasi-periodic oscillation (QPO) in the >1 keV flux, as well as flat-topped, band-limited noise breaking to a power law. The energy spectrum is again dominated by two components, a 0.16 keV thermal disk and a power law with an index of ∼2.5. These new measurements, combined with results from our previous 2006 January pointing in which we first detected QPOs, show for the first time in a ULX a pattern of spectral and temporal correlations strongly analogous to that seen in Galactic black hole (BH) sources, but at much higher X-ray luminosity and longer characteristic timescales. We find that the QPO frequency is proportional to the inferred disk flux, while the QPO and broadband noise amplitude (rms) are inversely proportional to the disk flux. Assuming that QPO frequency scales inversely with the BH mass at a given power-law spectral index we derive mass estimates using the observed QPO frequency-spectral index relations from five stellar-mass BH systems with dynamical mass constraints. The results from all sources are consistent with a mass range for NGC 5408 X-1 from 1000 to 9000 M sun . We argue that these are conservative limits, and a more likely range is from 2000 to 5000 M sun . Moreover, the recent relation from Gierlinski et al. that relates the BH mass to the strength of variability at high frequencies (above the break in the power spectrum) is also indicative of such a high mass for NGC 5408 X-1. Importantly, none of the above estimates appears consistent with a BH mass less than ∼1000 M sun for NGC 5408 X-1. We argue that these new findings strongly support the conclusion that NGC 5408 X-1 harbors an intermediate-mass BH.

EVOLUTION OF INTERMEDIATE-MASS X-RAY BINARIES DRIVEN BY THE MAGNETIC BRAKING OF AP/BP STARS. I. ULTRACOMPACT X-RAY BINARIES

Energy Technology Data Exchange (ETDEWEB)

Chen, Wen-Cong [School of Physics and Electrical Information, Shangqiu Normal University, Shangqiu 476000 (China); Podsiadlowski, Philipp, E-mail: chenwc@pku.edu.cn [Department of Physics, University of Oxford, Oxford OX1 3RH (United Kingdom)

2016-10-20

It is generally believed that ultracompact X-ray binaries (UCXBs) evolved from binaries consisting of a neutron star accreting from a low-mass white dwarf (WD) or helium star where mass transfer is driven by gravitational radiation. However, the standard WD evolutionary channel cannot produce the relatively long-period (40–60 minutes) UCXBs with a high time-averaged mass-transfer rate. In this work, we explore an alternative evolutionary route toward UCXBs, where the companions evolve from intermediate-mass Ap/Bp stars with an anomalously strong magnetic field (100–10,000 G). Including the magnetic braking caused by the coupling between the magnetic field and an irradiation-driven wind induced by the X-ray flux from the accreting component, we show that intermediate-mass X-ray binaries (IMXBs) can evolve into UCXBs. Using the MESA code, we have calculated evolutionary sequences for a large number of IMXBs. The simulated results indicate that, for a small wind-driving efficiency f = 10{sup −5}, the anomalous magnetic braking can drive IMXBs to an ultra-short period of 11 minutes. Comparing our simulated results with the observed parameters of 15 identified UCXBs, the anomalous magnetic braking evolutionary channel can account for the formation of seven and eight sources with f = 10{sup −3}, and 10{sup −5}, respectively. In particular, a relatively large value of f can fit three of the long-period, persistent sources with a high mass-transfer rate. Though the proportion of Ap/Bp stars in intermediate-mass stars is only 5%, the lifetime of the UCXB phase is ≳2 Gyr, producing a relatively high number of observable systems, making this an alternative evolutionary channel for the formation of UCXBs.

A next-to-leading-log Monte Carlo study of photon pairs and the search for the intermediate mass Higgs Boson

International Nuclear Information System (INIS)

Bailey, B.R.

1993-01-01

Symmetry breaking and the question of the origin of mass are the reasons the Superconducting Super Collider and the Large Hadron Collider are being built. The Standard Model of particle physics provides a solution to this problem by proposing the existence of a neutral scalar particle, the Higgs boson. This particle, via its interactions, gives mass to all of the particles in the Standard Model. The question of whether the Higgs boson can be detected at these machines depends critically on its final state decays. These decays in turn depend crucially on the mass of the Higgs boson, an unknown parameter of the theory. A lower bound of the Higgs mass has been set by experiment and a upper bound via theoretical arguments. Throughout much of the mass range Higgs decays via weak gauge bosons yield a clear signal. However, near the lower limit, the so-called intermediate mass region, the situation is less clear. In this region Higgs decays into photon pairs have been suggested as a viable signal. The significance of such a signal depends on other competing processes or backgrounds. This dissertation attempts to answer the question, open-quotes Can the Intermediate mass Higgs boson be detected via its electromagnetic decays?close quotes To answer this question various Standard Model processes are calculated to the leading-log and next-to-leading-log level in a Monte Carlo environment

Gravitational Waves and Intermediate-mass Black Hole Retention in Globular Clusters

Science.gov (United States)

Fragione, Giacomo; Ginsburg, Idan; Kocsis, Bence

2018-04-01

The recent discovery of gravitational waves (GWs) has opened new horizons for physics. Current and upcoming missions, such as LIGO, VIRGO, KAGRA, and LISA, promise to shed light on black holes of every size from stellar mass (SBH) sizes up to supermassive black holes. The intermediate-mass black hole (IMBH) family has not been detected beyond any reasonable doubt. Recent analyses suggest observational evidence for the presence of IMBHs in the centers of two Galactic globular clusters (GCs). In this paper, we investigate the possibility that GCs were born with a central IMBH, which undergoes repeated merger events with SBHs in the cluster core. By means of a semi-analytical method, we follow the evolution of the primordial cluster population in the galactic potential and the mergers of the binary IMBH-SBH systems. Our models predict ≈1000 IMBHs within 1 kpc from the galactic center and show that the IMBH-SBH merger rate density changes from { \\mathcal R }≈ 1000 Gpc‑3 yr‑1 beyond z ≈ 2 to { \\mathcal R }≈ 1{--}10 Gpc‑3 yr‑1 at z ≈ 0. The rates at low redshifts may be significantly higher if young massive star clusters host IMBHs. The merger rates are dominated by IMBHs with masses between 103 and 104 M ⊙. Currently, there are no LIGO/VIRGO upper limits for GW sources in this mass range, but our results show that at design sensitivity, these instruments will detect IMBH-SBH mergers in the coming years. LISA and the Einstein Telescope will be best suited to detect these events. The inspirals of IMBH-SBH systems may also generate an unresolved GW background.

X-Ray Emission from Active Galactic Nuclei with Intermediate-Mass Black Holes

Science.gov (United States)

Dewangan, G. C.; Mathur, S.; Griffiths, R. E.; Rao, A. R.

2008-12-01

We present a systematic X-ray study of eight active galactic nuclei (AGNs) with intermediate-mass black holes (MBH ~ 8-95 × 104 M⊙) based on 12 XMM-Newton observations. The sample includes the two prototype AGNs in this class—NGC 4395 and POX 52 and six other AGNs discovered with the Sloan Digitized Sky Survey. These AGNs show some of the strongest X-ray variability, with the normalized excess variances being the largest and the power density break timescales being the shortest observed among radio-quiet AGNs. The excess-variance-luminosity correlation appears to depend on both the BH mass and the Eddington luminosity ratio. The break timescale-black hole mass relations for AGN with IMBHs are consistent with that observed for massive AGNs. We find that the FWHM of the Hβ/Hα line is uncorrelated with the BH mass, but shows strong anticorrelation with the Eddington luminosity ratio. Four AGNs show clear evidence for soft X-ray excess emission (kTin ~ 150-200 eV). X-ray spectra of three other AGNs are consistent with the presence of the soft excess emission. NGC 4395 with lowest L/LEdd lacks the soft excess emission. Evidently small black mass is not the primary driver of strong soft X-ray excess emission from AGNs. The X-ray spectral properties and optical-to-X-ray spectral energy distributions of these AGNs are similar to those of Seyfert 1 galaxies. The observed X-ray/UV properties of AGNs with IMBHs are consistent with these AGNs being low-mass extensions of more massive AGNs, those with high Eddington luminosity ratio looking more like narrow-line Seyfert 1 s and those with low L/LEdd looking more like broad-line Seyfert 1 galaxies.

OPTICAL VARIABILITY OF THE ACCRETION DISK AROUND THE INTERMEDIATE-MASS BLACK HOLE ESO 243-49 HLX-1 DURING THE 2012 OUTBURST

Energy Technology Data Exchange (ETDEWEB)

Webb, N. A.; Godet, O.; Barret, D. [Université de Toulouse, UPS-OMP, IRAP, Toulouse (France); Wiersema, K. [University of Leicester, University Road, Leicester LE1 7RH (United Kingdom); Lasota, J.-P. [Institut d' Astrophysique de Paris, UMR 7095, CNRS, UPMC Université Paris 06, 98bis Boulevard Arago, F-75014 Paris (France); Farrell, S. A. [Sydney Institute for Astronomy, School of Physics, The University of Sydney, NSW 2006 (Australia); Maccarone, T. J. [Department of Physics, Box 41051, Texas Tech University, Lubbock TX 79409-1051 (United States); Servillat, M., E-mail: natalie.webb@irap.omp.eu [Laboratoire AIM (CEA/DSM/IRFU/SAp, CNRS, Université Paris Diderot), CEA Saclay, Bat. 709, F-91191 Gif-sur-Yvette (France)

2014-01-01

We present dedicated quasi-simultaneous X-ray (Swift) and optical (Very Large Telescope, V-, and R-band) observations of the intermediate-mass black hole candidate HLX-1 before and during the 2012 outburst. We show that the V-band magnitudes vary with time, thus proving that a portion of the observed emission originates in the accretion disk. Using the first quiescent optical observations of HLX-1, we show that the stellar population surrounding HLX-1 is fainter than V ∼ 25.1 and R ∼ 24.2. We show that the optical emission may increase before the X-ray emission consistent with the scenario proposed by Lasota et al. in which the regular outbursts could be related to the passage at periastron of a star circling the intermediate-mass black hole in an eccentric orbit, which triggers mass transfer into a quasi-permanent accretion disk around the black hole. Further, if there is indeed a delay in the X-ray emission we estimate the mass-transfer delivery radius to be ∼10{sup 11} cm.

Imaging mass spectrometry (IMS) of cortical lipids from preclinical to severe stages of Alzheimer's disease.

Science.gov (United States)

Gónzalez de San Román, E; Manuel, I; Giralt, M T; Ferrer, I; Rodríguez-Puertas, R

2017-09-01

Alzheimer's disease (AD) is a progressive neurodegenerative disease affecting millions of patients worldwide. Previous studies have demonstrated alterations in the lipid composition of lipid extracts from plasma and brain samples of AD patients. However, there is no consensus regarding the qualitative and quantitative changes of lipids in brains from AD patients. In addition, the recent developments in imaging mass spectrometry methods are leading to a new stage in the in situ analysis of lipid species in brain tissue slices from human postmortem samples. The present study uses the matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI-IMS), permitting the direct anatomical analysis of lipids in postmortem brain sections from AD patients, which are compared with the intensity of the lipid signal in samples from matched subjects with no neurological diseases. The frontal cortex samples from AD patients were classified in three groups based on Braak's histochemical criteria, ranging from non-cognitively impaired patients to those severely affected. The main results indicate a depletion of different sulfatide lipid species from the earliest stages of the disease in both white and gray matter areas of the frontal cortex. Therefore, the decrease in sulfatides in cortical areas could be considered as a marker of the disease, but may also indicate neurochemical modifications related to the pathogenesis of the disease. This article is part of a Special Issue entitled: Membrane Lipid Therapy: Drugs Targeting Biomembranes edited by Pablo V. Escribá. Copyright © 2017 Elsevier B.V. All rights reserved.

Searching for intermediate-mass black holes in galaxies with low-luminosity AGN: a multiple-method approach

Science.gov (United States)

Koliopanos, F.; Ciambur, B.; Graham, A.; Webb, N.; Coriat, M.; Mutlu-Pakdil, B.; Davis, B.; Godet, O.; Barret, D.; Seigar, M.

2017-10-01

Intermediate Mass Black Holes (IMBHs) are predicted by a variety of models and are the likely seeds for super massive BHs (SMBHs). However, we have yet to establish their existence. One method, by which we can discover IMBHs, is by measuring the mass of an accreting BH, using X-ray and radio observations and drawing on the correlation between radio luminosity, X-ray luminosity and the BH mass, known as the fundamental plane of BH activity (FP-BH). Furthermore, the mass of BHs in the centers of galaxies, can be estimated using scaling relations between BH mass and galactic properties. We are initiating a campaign to search for IMBH candidates in dwarf galaxies with low-luminosity AGN, using - for the first time - three different scaling relations and the FP-BH, simultaneously. In this first stage of our campaign, we measure the mass of seven LLAGN, that have been previously suggested to host central IMBHs, investigate the consistency between the predictions of the BH scaling relations and the FP-BH, in the low mass regime and demonstrate that this multiple method approach provides a robust average mass prediction. In my talk, I will discuss our methodology, results and next steps of this campaign.

Pathology interface for the molecular analysis of tissue by mass spectrometry

Directory of Open Access Journals (Sweden)

Jeremy L Norris

2016-01-01

Full Text Available Background: Imaging mass spectrometry (IMS generates molecular images directly from tissue sections to provide better diagnostic insights and expand the capabilities of clinical anatomic pathology. Although IMS technology has matured over recent years, the link between microscopy imaging currently used by pathologists and MS-based molecular imaging has not been established. Methods: We adapted the Vanderbilt University Tissue Core workflow for IMS into a web-based system that facilitates remote collaboration. The platform was designed to perform within acceptable web response times for viewing, annotating, and processing high resolution microscopy images. Results: We describe a microscopy-driven approach to tissue analysis by IMS. Conclusion: The Pathology Interface for Mass Spectrometry is designed to provide clinical access to IMS technology and deliver enhanced diagnostic value.

Robo-AO Kepler Asteroseismic Survey. I. Adaptive Optics Imaging of 99 Asteroseismic Kepler Dwarfs and Subgiants

Energy Technology Data Exchange (ETDEWEB)

Schonhut-Stasik, Jessica S.; Baranec, Christoph; Huber, Daniel; Atkinson, Dani; Hagelberg, Janis; Marel, Nienke van der; Hodapp, Klaus W. [Institute for Astronomy, University of Hawai‘i at Mānoa, Hilo, HI 96720-2700 (United States); Ziegler, Carl; Law, Nicholas M. [Department of Physics and Astronomy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3255 (United States); Gaidos, Eric [Department of Geology and Geophysics, University of Hawai‘i at Mānoa, Honolulu, HI 96822 (United States); Riddle, Reed, E-mail: jstasik@hawaii.edu [Division of Physics, Mathematics, and Astronomy, California Institute of Technology, Pasadena, CA 91125 (United States)

2017-10-01

We used the Robo-AO laser adaptive optics (AOs) system to image 99 main sequence and subgiant stars that have Kepler -detected asteroseismic signals. Robo-AO allows us to resolve blended secondary sources at separations as close as ∼0.″15 that may contribute to the measured Kepler light curves and affect asteroseismic analysis and interpretation. We report eight new secondary sources within 4.″0 of these Kepler asteroseismic stars. We used Subaru and Keck AOs to measure differential infrared photometry for these candidate companion systems. Two of the secondary sources are likely foreground objects, while the remaining six are background sources; however, we cannot exclude the possibility that three of the objects may be physically associated. We measured a range of i ′-band amplitude dilutions for the candidate companion systems from 0.43% to 15.4%. We find that the measured amplitude dilutions are insufficient to explain the previously identified excess scatter in the relationship between asteroseismic oscillation amplitude and the frequency of maximum power.

Inductive Monitoring System (IMS)

Data.gov (United States)

National Aeronautics and Space Administration — IMS: Inductive Monitoring System The Inductive Monitoring System (IMS) is a tool that uses a data mining technique called clustering to extract models of normal...

Integrating IMS LD and IMS QTIv2 using CopperCore Service Integration

NARCIS (Netherlands)

Vogten, Hubert

2006-01-01

Vogten, H. (2006). Integrating IMS LD and IMS QTIv2 using CopperCore Service Integration. Presentation at International Workshop in Learning Networks for Lifelong Competence Development. March, 30-31, 2006. Sofia, Bulgaria: TENCompetence Conference. Retrieved June 30th, 2006, from

An improvement of isochronous mass spectrometry: Velocity measurements using two time-of-flight detectors

International Nuclear Information System (INIS)

Shuai, P.; Xu, X.; Zhang, Y.H.; Xu, H.S.; Litvinov, Yu. A.; Wang, M.

2016-01-01

Isochronous mass spectrometry (IMS) in storage rings is a powerful tool for mass measurements of exotic nuclei with very short half-lives down to several tens of microseconds, using a multicomponent secondary beam separated in-flight without cooling. However, the inevitable momentum spread of secondary ions limits the precision of nuclear masses determined by using IMS. Therefore, the momentum measurement in addition to the revolution period of stored ions is crucial to reduce the influence of the momentum spread on the standard deviation of the revolution period, which would lead to a much improved mass resolving power of IMS. One of the proposals to upgrade IMS is that the velocity of secondary ions could be directly measured by using two time-of-flight (double TOF) detectors installed in a straight section of a storage ring. In this paper, we outline the principle of IMS with double TOF detectors and the method to correct the momentum spread of stored ions.

Separation of different ion structures in atmospheric pressure photoionization-ion mobility spectrometry-mass spectrometry (APPI-IMS-MS).

Science.gov (United States)

Laakia, Jaakko; Adamov, Alexey; Jussila, Matti; Pedersen, Christian S; Sysoev, Alexey A; Kotiaho, Tapio

2010-09-01

This study demonstrates how positive ion atmospheric pressure photoionization-ion mobility spectrometry-mass spectrometry (APPI-IMS-MS) can be used to produce different ionic forms of an analyte and how these can be separated. When hexane:toluene (9:1) is used as a solvent, 2,6-di-tert-butylpyridine (2,6-DtBPyr) and 2,6-di-tert-4-methylpyridine (2,6-DtB-4-MPyr) efficiently produce radical cations [M](+*) and protonated [M + H](+) molecules, whereas, when the sample solvent is hexane, protonated molecules are mainly formed. Interestingly, radical cations drift slower in the drift tube than the protonated molecules. It was observed that an oxygen adduct ion, [M + O(2)](+*), which was clearly seen in the mass spectra for hexane:toluene (9:1) solutions, shares the same mobility with radical cations, [M](+*). Therefore, the observed mobility order is most likely explained by oxygen adduct formation, i.e., the radical cation forming a heavier adduct. For pyridine and 2-tert-butylpyridine, only protonated molecules could be efficiently formed in the conditions used. For 1- and 2-naphthol it was observed that in hexane the protonated molecule typically had a higher intensity than the radical cation, whereas in hexane:toluene (9:1) the radical cation [M](+*) typically had a higher intensity than the protonated molecule [M + H](+). Interestingly, the latter drifts slower than the radical cation [M](+*), which is the opposite of the drift pattern seen for 2,6-DtBPyr and 2,6-DtB-4-MPyr. 2010 American Society for Mass Spectrometry. Published by Elsevier Inc. All rights reserved.

CHARACTERIZATION OF A SAMPLE OF INTERMEDIATE-TYPE ACTIVE GALACTIC NUCLEI. II. HOST BULGE PROPERTIES AND BLACK HOLE MASS ESTIMATES

Energy Technology Data Exchange (ETDEWEB)

Benitez, Erika; Cruz-Gonzalez, Irene; Martinez, Benoni; Jimenez-Bailon, Elena [Instituto de Astronomia, Universidad Nacional Autonoma de Mexico, Apdo. Postal 70-264, Mexico D.F. 04510 (Mexico); Mendez-Abreu, Jairo; Lopez-Martin, Luis [Instituto de Astrofisica de Canarias, E-38200 La Laguna, Tenerife (Spain); Fuentes-Carrera, Isaura [Escuela Superior de Fisica y Matematicas, Instituto Politecnico Nacional (ESFM-IPN), U.P. Adolfo Lopez Mateos, Mexico D.F. 07730 (Mexico); Chavushyan, Vahram [Instituto Nacional de Astrofisica, Optica y Electronica, Apdo. Postal 51-216, 72000 Puebla (Mexico); Leon-Tavares, Jonathan, E-mail: erika@astro.unam.mx [Aalto University Metsaehovi Radio Observatory, Metsaehovintie 114, 02540 Kylmaelae (Finland)

2013-02-15

We present a study of the host bulge properties and their relations with the black hole mass for a sample of 10 intermediate-type active galactic nuclei (AGNs). Our sample consists mainly of early-type spirals, four of them hosting a bar. For 70{sup +10} {sub -17}% of the galaxies, we have been able to determine the type of the bulge, and find that these objects probably harbor a pseudobulge or a combination of classical bulge/pseudobulge, suggesting that pseudobulges might be frequent in intermediate-type AGNs. In our sample, 50% {+-} 14% of the objects show double-peaked emission lines. Therefore, narrow double-peaked emission lines seem to be frequent in galaxies harboring a pseudobulge or a combination of classical bulge/pseudobulge. Depending on the bulge type, we estimated the black hole mass using the corresponding M {sub BH}-{sigma}* relation and found them within a range of 5.69 {+-} 0.21 < log M {sup {sigma}}*{sub BH} < 8.09 {+-} 0.24. Comparing these M {sup {sigma}}*{sub BH} values with masses derived from the FWHM of H{beta} and the continuum luminosity at 5100 A from their SDSS-DR7 spectra (M {sub BH}), we find that 8 out of 10 (80{sup +7} {sub -17}%) galaxies have black hole masses that are compatible within a factor of 3. This result would support that M {sub BH} and M {sup {sigma}}*{sub BH} are the same for intermediate-type AGNs, as has been found for type 1 AGNs. However, when the type of the bulge is taken into account, only three out of the seven (43{sup +18} {sub -15}%) objects of the sample have their M {sup {sigma}}*{sub BH} and M {sub BH} compatible within 3{sigma} errors. We also find that estimations based on the M {sub BH}-{sigma}* relation for pseudobulges are not compatible in 50% {+-} 20% of the objects.

Multifragmentation in intermediate energy heavy ion collisions

International Nuclear Information System (INIS)

Jacak, B.V.; Britt, H.C.; Claesson, G.

1986-01-01

There has been considerable recent interest in the production of intermediate mass fragments (A > 4) in intermediate and high energy nucleus-nucleus collisions. The mechanism for production of these fragments is not well understood and has been described by models employing a variety of assumptions. Some examples are: disassembly of a system in thermal equilibrium into nucleons and nuclear fragments, liquid-vapor phase transitions in nuclear matter, final state coalescence of nucleons and dynamical correlations between nucleons at breakup. Previous studies of fragment production, with one exception, have been single particle inclusive measurements; the observed fragment mass (or charge) distributions can be described by all of the models above. To gain insight into the fragment production mechanism, the authors used the GSI/LBL Plastic Ball detector system to get full azimuthal coverage for intermediate mass fragments in the forward hemisphere in the center of mass system while measuring all the light particles in each event. The authors studied the systems 200 MeV/nucleon Au + Au and Au + Fe

Observational properties of models of semidetached close binaries. Pt. 2

International Nuclear Information System (INIS)

Giannone, P.; Giannuzzi, M.A.; Pucillo, M.

1975-01-01

Binaries of Cases A and B with intermediate and small masses have been studied. Synthetic light curves are shown to be affected mainly by the assumption concerning the shape of the components. The comparison between synthetic light curves and observed data can give further information on the reliability of the hypotheses assumed in the computations of binary star evolution. The calculated properties lead to useful indications about the evolutionary stages of observed binaries. The detection of systems evolving according to Case A appears to be favoured in comparison with that of systems of Case B. Systems with undersize subgiants result comparatively difficult to observe. (orig./BJ) [de

The distribution of stars around the Milky Way's central black hole. II. Diffuse light from sub-giants and dwarfs

Science.gov (United States)

Schödel, R.; Gallego-Cano, E.; Dong, H.; Nogueras-Lara, F.; Gallego-Calvente, A. T.; Amaro-Seoane, P.; Baumgardt, H.

2018-01-01

Context. This is the second of three papers that search for the predicted stellar cusp around the Milky Way's central black hole, Sagittarius A*, with new data and methods. Aims: We aim to infer the distribution of the faintest stellar population currently accessible through observations around Sagittarius A*. Methods: We used adaptive optics assisted high angular resolution images obtained with the NACO instrument at the ESO VLT. Through optimised PSF fitting we removed the light from all detected stars above a given magnitude limit. Subsequently we analysed the remaining, diffuse light density. Systematic uncertainties were constrained by the use of data from different observing epochs and obtained with different filters. We show that it is necessary to correct for the diffuse emission from the mini-spiral, which would otherwise lead to a systematically biased light density profile. We used a Paschen α map obtained with the Hubble Space Telescope for this purpose. Results: The azimuthally averaged diffuse surface light density profile within a projected distance of R ≲ 0.5 pc from Sagittarius A* can be described consistently by a single power law with an exponent of Γ = 0.26 ± 0.02stat ± 0.05sys, similar to what has been found for the surface number density of faint stars in Paper I. Conclusions: The analysed diffuse light arises from sub-giant and main-sequence stars with Ks ≈ 19-22 with masses of 0.8-1.5 M⊙. These stars can be old enough to be dynamically relaxed. The observed power-law profile and its slope are consistent with the existence of a relaxed stellar cusp around the Milky Way's central black hole. We find that a Nuker law provides an adequate description of the nuclear cluster's intrinsic shape (assuming spherical symmetry). The 3D power-law slope near Sgr A* is γ = 1.13 ± 0.03model ± 0.05sys. The stellar density decreases more steeply beyond a break radius of about 3 pc, which corresponds roughly to the radius of influence of the

A midrapidity source of intermediate mass fragments in highly central collisions of Au+Au at 150 A MeV

Energy Technology Data Exchange (ETDEWEB)

Alard, J P; Bastid, N; Crouau, M; Dupieux, P; Fraysse, L; Jorio, M; Montarou, G; Morel, P [Laboratoire de Physique Corpusculaire, 63 - Clermont-Ferrand (France); Basrak, Z; Caplar, R; Cindro, N; Hoelbling, S [Rudjer Boskovic Inst., Zagreb (Yugoslavia); Belayev, I M; Frolov, S; Korchagin, Y; Lebedev, A; Smolyankin, S; Zhilin, A V [Institute for Experimental and Theoretical Physics, Moscow (Russia); Bini, M; Olmi, A; Pasquali, G; Poggi, G; Taccetti, N [Florence Univ. (Italy); [INFN, Florence (Italy); Blaich, T [Mainz Univ. (Germany); Buta, A; Legrand, I; Moisa, D; Petrovici, M; Simion, V [Institute for Physics and Nuclear Engineering, Bucharest (Romania); Cerruti, C; Coffin, J P; Fintz, P; Guillaume, G; Houari, O; Jundt, F; Kuhn, C; Maguire, C; Rami, F; Tezkratt, R; Wagner, P [Centre de Recherches Nucleaires, 67 - Strasbourg (France); [Strasbourg Univ., 67 (France); Eroe, J; Fodor, Z; Kecskemeti, J; Koncz, P; Seres, Z [Central Research Inst. for Physics, Budapest (Hungary); Grigoriyan, Y; Manko, V; Mgebrishvili, G; Sadchikov, A; Vasiliev, M A [Kurchatov Inst. for Atomic Energy, Moscow (Russia); Herrmann, N; Pelte, D; Trzaska, M; Wienold, T [Heidelberg Univ. (Germany). Physikalisches Inst.; Kotte, R; Moesner, J; Neubert, W; Wohlfarth, D [Forschungszentrum Rossendorf (Germany); Matulewicz, T; Sikora, B; Wilhelmi, Z [Warsaw Univ. (Poland). Inst. of Experimental Physics; Bock, R; Fan, Z G; Freifelder, R; Gobbi, A; Hildenbrand, K D; Jeong, S C; Kraemer, M; Reisdorf, W; Schuell, D; Sodan, U; Teh, K; Wessels, J P; FOPI Collaboration at GSI

1992-02-01

Charged particles have been observed in collisions of Au on Au at incident energy of 150 A MeV using a high-granularity detector system covering approximatley the forward hemisphere in the center-of-mass system. Highly central collisions have been studied using a double selection criterion which combines large charged particle multiplicities with small transverse momentum directivities. In this class of events about one quarter of the total nuclear charge emerges as intermediate mass fragments with nuclear charges Z>2. These fragments are centred at midrapidity and are produced with large transverse velocities. (orig.).

A midrapidity source of intermediate mass fragments in highly central collisions of Au+Au at 150 A MeV

International Nuclear Information System (INIS)

Alard, J.P.; Bastid, N.; Crouau, M.; Dupieux, P.; Fraysse, L.; Jorio, M.; Montarou, G.; Morel, P.; Basrak, Z.; Caplar, R.; Cindro, N.; Hoelbling, S.; Belayev, I.M.; Frolov, S.; Korchagin, Y.; Lebedev, A.; Smolyankin, S.; Zhilin, A.V.; Bini, M.; Olmi, A.; Pasquali, G.; Poggi, G.; Taccetti, N.; Blaich, T.; Buta, A.; Legrand, I.; Moisa, D.; Petrovici, M.; Simion, V.; Cerruti, C.; Coffin, J.P.; Fintz, P.; Guillaume, G.; Houari, O.; Jundt, F.; Kuhn, C.; Maguire, C.; Rami, F.; Tezkratt, R.; Wagner, P.; Eroe, J.; Fodor, Z.; Kecskemeti, J.; Koncz, P.; Seres, Z.; Grigoriyan, Y.; Manko, V.; Mgebrishvili, G.; Sadchikov, A.; Vasiliev, M.A.; Herrmann, N.; Pelte, D.; Trzaska, M.; Wienold, T.; Matulewicz, T.; Sikora, B.; Wilhelmi, Z.; Bock, R.; Fan, Z.G.; Freifelder, R.; Gobbi, A.; Hildenbrand, K.D.; Jeong, S.C.; Kraemer, M.; Reisdorf, W.; Schuell, D.; Sodan, U.; Teh, K.; Wessels, J.P.

1992-02-01

Charged particles have been observed in collisions of Au on Au at incident energy of 150 A MeV using a high-granularity detector system covering approximatley the forward hemisphere in the center-of-mass system. Highly central collisions have been studied using a double selection criterion which combines large charged particle multiplicities with small transverse momentum directivities. In this class of events about one quarter of the total nuclear charge emerges as intermediate mass fragments with nuclear charges Z>2. These fragments are centred at midrapidity and are produced with large transverse velocities. (orig.)

Compressed sensing in imaging mass spectrometry

International Nuclear Information System (INIS)

Bartels, Andreas; Dülk, Patrick; Trede, Dennis; Alexandrov, Theodore; Maaß, Peter

2013-01-01

Imaging mass spectrometry (IMS) is a technique of analytical chemistry for spatially resolved, label-free and multipurpose analysis of biological samples that is able to detect the spatial distribution of hundreds of molecules in one experiment. The hyperspectral IMS data is typically generated by a mass spectrometer analyzing the surface of the sample. In this paper, we propose a compressed sensing approach to IMS which potentially allows for faster data acquisition by collecting only a part of the pixels in the hyperspectral image and reconstructing the full image from this data. We present an integrative approach to perform both peak-picking spectra and denoising m/z-images simultaneously, whereas the state of the art data analysis methods solve these problems separately. We provide a proof of the robustness of the recovery of both the spectra and individual channels of the hyperspectral image and propose an algorithm to solve our optimization problem which is based on proximal mappings. The paper concludes with the numerical reconstruction results for an IMS dataset of a rat brain coronal section. (paper)

Prospects for detection of intermediate-mass black holes in globular clusters using integrated-light spectroscopy

Science.gov (United States)

de Vita, R.; Trenti, M.; Bianchini, P.; Askar, A.; Giersz, M.; van de Ven, G.

2017-06-01

The detection of intermediate-mass black holes (IMBHs) in Galactic globular clusters (GCs) has so far been controversial. In order to characterize the effectiveness of integrated-light spectroscopy through integral field units, we analyse realistic mock data generated from state-of-the-art Monte Carlo simulations of GCs with a central IMBH, considering different setups and conditions varying IMBH mass, cluster distance and accuracy in determination of the centre. The mock observations are modelled with isotropic Jeans models to assess the success rate in identifying the IMBH presence, which we find to be primarily dependent on IMBH mass. However, even for an IMBH of considerable mass (3 per cent of the total GC mass), the analysis does not yield conclusive results in one out of five cases, because of shot noise due to bright stars close to the IMBH line of sight. This stochastic variability in the modelling outcome grows with decreasing BH mass, with approximately three failures out of four for IMBHs with 0.1 per cent of total GC mass. Finally, we find that our analysis is generally unable to exclude at 68 per cent confidence an IMBH with mass of 103 M⊙ in snapshots without a central BH. Interestingly, our results are not sensitive to GC distance within 5-20 kpc, nor to misidentification of the GC centre by less than 2 arcsec (<20 per cent of the core radius). These findings highlight the value of ground-based integral field spectroscopy for large GC surveys, where systematic failures can be accounted for, but stress the importance of discrete kinematic measurements that are less affected by stochasticity induced by bright stars.

Evolving ONe WD+He star systems to intermediate-mass binary pulsars

Science.gov (United States)

Liu, D.; Wang, B.; Chen, W.; Zuo, Z.; Han, Z.

2018-06-01

It has been suggested that accretion-induced collapse (AIC) is a non-negligible path for the formation of the observed neutron stars (NSs). An ONe white dwarf (WD) that accretes material from a He star may experience AIC process and eventually produce intermediate-mass binary pulsars (IMBPs), named as the ONe WD+He star scenario. Note that previous studies can only account for part of the observed IMBPs with short orbital periods. In this work, we investigate the evolution of about 900 ONe WD+He star binaries to explore the distribution of IMBPs. We found that the ONe WD+He star scenario could form IMBPs including pulsars with 5-340 ms spin periods and 0.75-1.38 M_{⊙} WD companions, in which the orbital periods range from 0.04 to 900 d. Compared with the 20 observed IMBPs, this scenario can cover the parameters of 13 sources in the final orbital period-WD mass plane and the Corbet diagram, most of which have short orbital periods. We found that the ONe WD+He star scenario can explain almost all the observed IMBPs with short orbital periods. This work can well match the observed parameters of PSR J1802-2124 (one of the two precisely observed IMBPs), providing a possible evolutional path for its formation. We also speculate that the compact companion of HD 49798 (a hydrogen depleted sdO6 star) may be not a NS based on this work.

Resilience in IMS

DEFF Research Database (Denmark)

Kamyod, Chayapol; Nielsen, Rasmus Hjorth; Prasad, Neeli R.

2012-01-01

) and supporting always on services. Therefore, not only Quality of Service (QoS) but also resilience is required. In this paper, we attempt to evaluate and analyze end-to-end reliability of the IMS system using a model proposed as a combination of Reliability Block Diagram (RBD) and Markov Reward Models (MRMs......Reliability evaluation of systems has been widely researched for improving system resilience especially in designing processes of a complex system. The convergence of different access networks is possible via IP Multimedia Subsystem (IMS) for development toward Next Generation Networks (NGNs......). The resilience of the IMS architecture is studied by applying 1:1 redundancy at different communication scenarios between end users within and across communication domains. The model analysis provides useful reliability characteristics of the system and can be further applied for system design processes....

Delegation und Kooperation im Gesundheitswesen

OpenAIRE

Rosenau, Henning

2010-01-01

Delegation und Kooperation im Gesundheitswesen. - In: Tıpta işbirliği ve hukuksal sorunlar = Delegation und Kooperation im Gesundheitswesen / ed.: Hakan Hakeri ... - Samsun : Adalet, 2010. - S. 7-18

Innovationsmanagement im Marketing: Anleitung zur Innovations-Sensibilisierung und deren Umsetzung im Rahmen der Neuen Lernkultur

OpenAIRE

Mangisch, Christian; Blatter, Martin

2009-01-01

Der Kurs “Innovationsmanagement im Marketing“ vermittelt den Teilnehmenden Wissen zum Innovationsmanagement, zum innovativen Team und zu innovativen Marketing Trends. Diese Kurse sind online auf dem folgenden Link www.ritzycampus.ch zu finden. Die Teilnehmer müssen für den Online-Kurs keine speziellen Kenntnisse oder Voraussetzungen mitbringen. Diese Online-Kurse im Fach Marketing sind an ein breites Publikum gerichtet. Sie ermöglichen den Studierenden im Eigenstudium die Grundlagen der Theme...

Δim-lacunary statistical convergence of order α

Science.gov (United States)

Altınok, Hıfsı; Et, Mikail; Işık, Mahmut

2018-01-01

The purpose of this work is to introduce the concepts of Δim-lacunary statistical convergence of order α and lacunary strongly (Δim,p )-convergence of order α. We establish some connections between lacunary strongly (Δim,p )-convergence of order α and Δim-lacunary statistical convergence of order α. It is shown that if a sequence is lacunary strongly (Δim,p )-summable of order α then it is Δim-lacunary statistically convergent of order α.

Sensitivity of gravitational wave searches to the full signal of intermediate-mass black hole binaries during the first observing run of Advanced LIGO

Science.gov (United States)

Calderón Bustillo, Juan; Salemi, Francesco; Dal Canton, Tito; Jani, Karan P.

2018-01-01

The sensitivity of gravitational wave searches for binary black holes is estimated via the injection and posterior recovery of simulated gravitational wave signals in the detector data streams. When a search reports no detections, the estimated sensitivity is then used to place upper limits on the coalescence rate of the target source. In order to obtain correct sensitivity and rate estimates, the injected waveforms must be faithful representations of the real signals. Up to date, however, injected waveforms have neglected radiation modes of order higher than the quadrupole, potentially biasing sensitivity and coalescence rate estimates. In particular, higher-order modes are known to have a large impact in the gravitational waves emitted by intermediate-mass black holes binaries. In this work, we evaluate the impact of this approximation in the context of two search algorithms run by the LIGO Scientific Collaboration in their search for intermediate-mass black hole binaries in the O1 LIGO Science Run data: a matched filter-based pipeline and a coherent unmodeled one. To this end, we estimate the sensitivity of both searches to simulated signals for nonspinning binaries including and omitting higher-order modes. We find that omission of higher-order modes leads to biases in the sensitivity estimates which depend on the masses of the binary, the search algorithm, and the required level of significance for detection. In addition, we compare the sensitivity of the two search algorithms across the studied parameter space. We conclude that the most recent LIGO-Virgo upper limits on the rate of coalescence of intermediate-mass black hole binaries are conservative for the case of highly asymmetric binaries. However, the tightest upper limits, placed for nearly equal-mass sources, remain unchanged due to the small contribution of higher modes to the corresponding sources.

[Kriegsland im Osten Eroberung, Kolonisierung und Militärherrschaft im Ersten Weltkrieg] / Markus Pöhlmann

Index Scriptorium Estoniae

Pöhlmann, Markus

2003-01-01

Rets.: Vejas Gabriel Liulevicius. Kriegsland im Osten Eroberung, Kolonisierung und Militärherrschaft im Ersten Weltkrieg. Aus dem Amerikanischen von Jürgen Bauer, Edith Nerke und Fee Engemann. Hamburg : 2002

CopperCore Service Integration, Integrating IMS Learning Design and IMS Question and Test Interoperability

NARCIS (Netherlands)

Vogten, Hubert; Martens, Harrie; Nadolski, Rob; Tattersall, Colin; Van Rosmalen, Peter; Koper, Rob

2006-01-01

Vogten, H., Martens, H., Nadolski, R., Tattersall, C., Rosmalen, van, P., Koper, R., (2006). CopperCore Service Integration, Integrating IMS Learning Design and IMS Question and Test Interoperability. Proceedings of the 6th IEEE International Conference on Advanced Learning Technologies (pp.

Volatility study of [C1C1im][NTf2] and [C2C3im][NTf2] ionic liquids

International Nuclear Information System (INIS)

Rocha, Marisa A.A.; Ribeiro, Filipe M.S.; Schröder, Bernd; Coutinho, João A.P.; Santos, Luís M.N.B.F.

2014-01-01

Highlights: • Vapor pressures of [C 1 C 1 im][NTf 2 ] and [C 2 C 3 im][NTf 2 ] ionic liquids are reported. • [C 1 C 1 im][NTf 2 ] presents higher enthalpy and entropy of vaporization than expected. • The high volatility of [C 2 C 3 im][NTf 2 ] is a result from its asymmetric character. -- Abstract: Vapor pressures of 1,3-dimethylimidazolium bis(trifluoromethylsulfonyl)imide, ([C 1 C 1 im][NTf 2 ]) and 1-ethyl-3-propylimidazolium bis(trifluoromethylsulfonyl)imide, ([C 2 C 3 im][NTf 2 ]) ionic liquids were measured as a function of temperature using a Knudsen effusion apparatus combined with a quartz crystal microbalance. Enthalpies and entropies of vaporization were derived from the fitting of vapor pressure and temperature results to the Clarke and Glew equation. [C 1 C 1 im][NTf 2 ] presents a higher enthalpy and entropy of vaporization than the neighboring members of the series. The enthalpy of vaporization of [C 2 C 3 im][NTf 2 ] lies in between the asymmetric and symmetric ionic liquid series, reflecting a decrease in the electrostatic interactions due to a decrease of the charge accessibility between the ionic pairs when the methyl group is replaced by an ethyl group. The obtained higher volatility of [C 2 C 3 im][NTf 2 ] arises from its asymmetric character, leading to an higher entropic contribution that compensates the enthalpic penalty. The border conditions ([C 1 C 1 im][NTf 2 ], [C 2 C 1 im][NTf 2 ] and [C 2 C 2 im][NTf 2 ]), topology ([C 2 C 3 im][NTf 2 ]) and symmetry/asymmetry of the ILs effect were evaluated and rationalized based on a comparative analysis of the thermodynamic properties, enthalpies and entropies of vaporization

Ion mobility analyzer - quadrupole mass spectrometer system design

International Nuclear Information System (INIS)

Cuna, C; Leuca, M; Lupsa, N; Mirel, V; Cuna, Stela; Cosma, V; Tusa, Florina; Bocos-Bintintan, V

2009-01-01

Because of their extremely high sensitivity for chemicals with elevated electronegativity or high proton affinity the ion mobility analysers are ideal for the ultra-trace detection of toxic or explosive chemicals, most of these situated often at concentration levels of sub-ppb (parts-per-billion). Ion mobility spectrometers (IMS) can be used to identify illicit drugs or environmental pollutants. Since resolution of an IMS is relatively low, to achieve an accurate identification of target analyte it is recommended to couple the IMS with a quadrupole mass spectrometer (QMS) or a time of flight mass spectrometer, acquiring in this way confirmatory information. This coupling is made through a specific interface. In this paper, an experimental model of such a tandem instrument, IMS-QMS is described. Accomplishment of this general purpose will be done, overcoming a series of specific issues. This implies the solving, using innovative solutions, of a series of complex issues: ensuring the stability of the ions beam generated by ion source; transfer with a good efficiency of the ionic current from IMS analyser to QMS; and realization of a special electronic circuitry which will be able to detect both positive and negative ions.

Ion mobility analyzer - quadrupole mass spectrometer system design

Energy Technology Data Exchange (ETDEWEB)

Cuna, C; Leuca, M; Lupsa, N; Mirel, V; Cuna, Stela; Cosma, V; Tusa, Florina [National Institute for Research and Development of Isotopic and Molecular Technologies, 65-103 Donath, 400293 Cluj-Napoca (Romania); Bocos-Bintintan, V, E-mail: cornel.cuna@itim-cj.r [Babes-Bolyai University, Faculty of Environmental Sciences, 3 Fantanele, 400294 Cluj Napoca (Romania)

2009-08-01

Because of their extremely high sensitivity for chemicals with elevated electronegativity or high proton affinity the ion mobility analysers are ideal for the ultra-trace detection of toxic or explosive chemicals, most of these situated often at concentration levels of sub-ppb (parts-per-billion). Ion mobility spectrometers (IMS) can be used to identify illicit drugs or environmental pollutants. Since resolution of an IMS is relatively low, to achieve an accurate identification of target analyte it is recommended to couple the IMS with a quadrupole mass spectrometer (QMS) or a time of flight mass spectrometer, acquiring in this way confirmatory information. This coupling is made through a specific interface. In this paper, an experimental model of such a tandem instrument, IMS-QMS is described. Accomplishment of this general purpose will be done, overcoming a series of specific issues. This implies the solving, using innovative solutions, of a series of complex issues: ensuring the stability of the ions beam generated by ion source; transfer with a good efficiency of the ionic current from IMS analyser to QMS; and realization of a special electronic circuitry which will be able to detect both positive and negative ions.

Application of Hadamard transform in IMS

International Nuclear Information System (INIS)

Sha Miaomiao; Liu Weihao; Chen Yong; Jiang Dazhen

2008-01-01

Hadamard transform can improve the SNR by increasing the ion duty cycle in IMS. In this paper, the ion spectral signals were processed by Hadamard transform based on the IMS detector hardware platform. The results showed that Hadamard transform can greatly improve the SNR of the IMS detector in contrast with traditional method. (authors)

A mass spectrometer based explosives trace detector

Science.gov (United States)

Vilkov, Andrey; Jorabchi, Kaveh; Hanold, Karl; Syage, Jack A.

2011-05-01

In this paper we describe the application of mass spectrometry (MS) to the detection of trace explosives. We begin by reviewing the issue of explosives trace detection (ETD) and describe the method of mass spectrometry (MS) as an alternative to existing technologies. Effective security screening devices must be accurate (high detection and low false positive rate), fast and cost effective (upfront and operating costs). Ion mobility spectrometry (IMS) is the most commonly deployed method for ETD devices. Its advantages are compact size and relatively low price. For applications requiring a handheld detector, IMS is an excellent choice. For applications that are more stationary (e.g., checkpoint and alternatives to IMS are available. MS is recognized for its superior performance with regard to sensitivity and specificity, which translate to lower false negative and false positive rates. In almost all applications outside of security where accurate chemical analysis is needed, MS is usually the method of choice and is often referred to as the gold standard for chemical analysis. There are many review articles and proceedings that describe detection technologies for explosives. 1,2,3,4 Here we compare MS and IMS and identify the strengths and weaknesses of each method. - Mass spectrometry (MS): MS offers high levels of sensitivity and specificity compared to other technologies for chemical detection. Its traditional disadvantages have been high cost and complexity. Over the last few years, however, the economics have greatly improved and MS is now capable of routine and automated operation. Here we compare MS and IMS and identify the strengths and weaknesses of each method. - Ion mobility spectrometry (IMS): 5 MS-ETD Screening System IMS is similar in concept to MS except that the ions are dispersed by gas-phase viscosity and not by molecular weight. The main advantage of IMS is that it does not use a vacuum system, which greatly reduces the size, cost, and complexity

Behavior of Abundances in Chemically Peculiar Dwarf and Subgiant A-Type Stars: HD 23193 and HD 170920

Science.gov (United States)

Kılıçoğlu, Tolgahan; Çalışkan, Şeyma; Ünal, Kübraözge

2018-01-01

To understand the origin of the abundance peculiarities of non-magnetic A-type stars, we present the first detailed chemical abundance analysis of a metallic line star HD 23193 (A2m) and an A-type subgiant HD 170920 (A5), which could have been a HgMn star on the main sequence. Our analysis is based on medium (R ∼ 14,000) and high (R ∼ 40,000) resolution spectroscopic data of the stars. The abundances of 18 elements are derived: C, O, Na, Mg, Al, Si, S, Ca, Sc, Ti, Cr, Mn, Fe, Ni, Zn, Sr, Y, and Ba. The masses of HD 23193 and HD 170920 are estimated from evolutionary tracks as 2.3 ± 0.1 M ⊙ and 2.9 ± 0.1 M ⊙. The ages are found to be 635 ± 33 Myr for HD 23193 and 480 ± 50 Myr for HD 170920 using isochrones. The abundance pattern of HD 23193 shows deviations from solar values in the iron-peak elements and indicates remarkable overabundances of Sr (1.16), Y (1.03), and Ba (1.24) with respect to the solar abundances. We compare the derived abundances of this moderately rotating (v\\sin i =37.5 km s‑1) Am star to the theoretical chemical evolution models including rotational mixing. The theoretically predicted abundances resemble our derived abundance pattern, except for a few elements (Si and Cr). For HD 170920, we find nearly solar abundances, except for C (‑0.43), S (0.16), Ti (0.15), Ni (0.16), Zn (0.41), Y (0.57), and Ba (0.97). Its low rotational velocity (v\\sin i=14.5 km s‑1), reduced carbon abundance, and enhanced heavy element abundances suggest that the star is most likely an evolved HgMn star. Based on observations made at the TÜBITAK National Observatory (Program ID 14BRTT150–671), and the Ankara University Observatory, Turkey.

Evaluation of SDS depletion using an affinity spin column and IMS-MS detection

Energy Technology Data Exchange (ETDEWEB)

Hengel, Shawna M.; Floyd, Erica A.; Baker, Erin Shammel; Zhao, Rui; Wu, Si; Pasa-Tolic, Ljiljana

2012-11-01

While the use of detergents is necessary for a variety of protein isolation preparation protocols, often prior to mass spectral (MS) analysis, they are not compatible with MS analysis due to ion suppression and adduct formation. This manuscript describes optimization of detergent removal, using commercially available SDS depletion spin columns containing an affinity resin, providing for both increased protein recovery and thorough SDS removal. Ion mobility spectrometry coupled with mass spectrometry (IMS-MS) allowed for a concurrent analysis of both analyte and detergent. In the case of both proteins and peptides, higher detergent concentrations than previously reported provided an increase of sample recovery; however there was a limit as SDS was detected by IMS-MS at higher levels of SDS indicating incomplete detergent depletion. The results also suggest optimal conditions for SDS removal are dependent on the sample concentration. Overall, this study provides a useful guide for proteomic studies where SDS is required for efficient sample preparation.

E2eUberIM

DEFF Research Database (Denmark)

Wac, Katarzyna; Cummings, Mark; Dey, Jayanta

2016-01-01

, high-quality services, we propose an innovative end-to-end service management framework called e2eUberIM. This framework contains a scalable, flexible, and volatile information model (UberIM) and a real-time, "organic" communication and storage process (e2eUber). It leverages the proprietary interfaces...... of different vendors, enabling the resulting enhanced operations system environment to automatically and in real-time optimize operational overhead while maximizing the user experience, and quickly field new innovative, composed "any-services" (XaaS). We document the e2eUberIM requirements and its design...

Imágenes e identidades

OpenAIRE

Guerrini, Sebastión

2013-01-01

Las identidades se estructuran en un proceso de identificación continua con imágenes. Esto afecta no solo a las identidades de las personas, sino también a las de las instituciones, organizaciones y empresas. En este sentido, el rol de ser del Diseño en Comunicación Visual es intentar afectar a las identidades de los espectadores de sus imágenes. Por esta razón, primero es importante definir qué son las imágenes. Facultad de Bellas Artes

λ (Δim) -statistical convergence of order α

Science.gov (United States)

Colak, Rifat; Et, Mikail; Altin, Yavuz

2017-09-01

In this study, using the generalized difference operator Δim and a sequence λ = (λn) which is a non-decreasing sequence of positive numbers tending to ∞ such that λn+1 ≤ λn+1, λ1 = 1, we introduce the concepts of λ (Δim) -statistical convergence of order α (α ∈ (0, 1]) and strong λ (Δim) -Cesàro summablility of order α (α > 0). We establish some connections between λ (Δim) -statistical convergence of order α and strong λ (Δim) -Cesàro summablility of order α. It is shown that if a sequence is strongly λ (Δim) -Cesàro summable of order α, then it is λ (Δim) -statistically convergent of order β in case 0 < α ≤ β ≤ 1.

Advanced Interval Management (IM) Concepts of Operations

Science.gov (United States)

Barmore, Bryan E.; Ahmad, Nash'at N.; Underwood, Matthew C.

2014-01-01

This document provides a high-level description of several advanced IM operations that NASA is considering for future research and development. It covers two versions of IM-CSPO and IM with Wake Mitigation. These are preliminary descriptions to support an initial benefits analysis

Search for Gravitational Wave Ringdowns from Perturbed Intermediate Mass Black Holes in LIGO-Virgo Data from 2005-2010

Science.gov (United States)

Aasi, J.; Abbott, B. P.; Abbott, R.; Abbott, T.; Abernathy, M. R.; Acernese, F.; Blackburn, Lindy L.; Camp, J. B.; Gehrels, N.; Graff, P. B.

2014-01-01

We report results from a search for gravitational waves produced by perturbed intermediate mass black holes (IMBH) in data collected by LIGO and Virgo between 2005 and 2010. The search was sensitive to astrophysical sources that produced damped sinusoid gravitational wave signals, also known as ringdowns, with frequency 50 less than or equal to italic f0/Hz less than or equal to 2000 and decay timescale 0.0001 approximately less than t/s approximately less than 0.1 characteristic of those produced in mergers of IMBH pairs. No significant gravitational wave candidate was detected. We report upper limits on the astrophysical coalescence rates of IMBHs with total binary mass 50 less than or equal to M/solar mass less than or equal to 450 and component mass ratios of either 1:1 or 4:1. For systems with total mass 100 less than or equal to M/solar mass 150, we report a 90%-confidence upper limit on the rate of binary IMBH mergers with non-spinning and equal mass components of 6:9 x 10(exp 8) Mpc(exp -3)yr(exp -1). We also report a rate upper limit for ringdown waveforms from perturbed IMBHs, radiating 1% of their mass as gravitational waves in the fundamental, l=m=2, oscillation mode, that is nearly three orders of magnitude more stringent than previous results.

Search for gravitational wave ringdowns from perturbed intermediate mass black holes in LIGO-Virgo data from 2005-2010

OpenAIRE

Aasi, J.; Abbott, B.; Abbott, R.; Abbott, T.; Abernathy, M.; Acernese, F.; Ackley, K.; Adams, C.; Adams, T.; Addesso, P.; Adhikari, R.; Affeldt, C.; Agathos, M.; Aggarwal, N.; Aguiar, O.

2014-01-01

We report results from a search for gravitational waves produced by perturbed intermediate mass black holes (IMBH) in data collected by LIGO and Virgo between 2005 and 2010. The search was sensitive to astrophysical sources that produced damped sinusoid gravitational wave signals, also known as ringdowns, with frequency $50\\le f_{0}/\\mathrm{Hz} \\le 2000$ and decay timescale $0.0001\\lesssim \\tau/\\mathrm{s} \\lesssim 0.1$ characteristic of those produced in mergers of IMBH pairs. No significant ...

Integrating IMS Learning Design and IMS Question and Test Interoperability using CopperCore Service Integration

NARCIS (Netherlands)

Vogten, Hubert; Martens, Harrie; Nadolski, Rob; Tattersall, Colin; Van Rosmalen, Peter; Koper, Rob

2006-01-01

Please, cite this publication as: Vogten, H., Martens, H., Nadolski, R., Tattersall, C., van Rosmalen, P., & Koper, R. (2006). Integrating IMS Learning Design and IMS Question and Test Interoperability using CopperCore Service Integration. Proceedings of International Workshop in Learning Networks

Abandoning the ship: spontaneous mass exodus of Clinostomum complanatum (Rudolphi, 1814) progenetic metecercariae from the dying intermediate host Trichogaster fasciatus (Bloch & Schneider, 1801).

Science.gov (United States)

Rizvi, Asim; Alam, Md Maroof; Parveen, Saltanat; Saleemuddin, M; Abidi, S M A

2012-04-01

The dramatic and spontaneous exodus of live Clinostomum complanatum progenetic metacercaria from the gill slits of the dying intermediate host, Trichogaster fasciatus is reported. Basic water parameter tests for dissolved oxygen, pH and temperature revealed slightly lower level of dissolved oxygen in tank water used for water change. To the best of our knowledge, it is the first report of a digenean metacercariae, en mass leaving their intermediate host, upon its death in search of an alternative host to support their survival and help in continuing their life cycle.

Determination of ion mobility collision cross sections for unresolved isomeric mixtures using tandem mass spectrometry and chemometric deconvolution

Energy Technology Data Exchange (ETDEWEB)

Harper, Brett [Institute of Biomedical Studies, Baylor University, Waco, TX 76798 (United States); Neumann, Elizabeth K. [Department of Chemistry and Biochemistry, Baylor University, Waco, TX 76798 (United States); Stow, Sarah M.; May, Jody C.; McLean, John A. [Department of Chemistry, Vanderbilt University, Nashville, TN 37235 (United States); Vanderbilt Institute of Chemical Biology, Nashville, TN 37235 (United States); Vanderbilt Institute for Integrative Biosystems Research and Education, Nashville, TN 37235 (United States); Center for Innovative Technology, Nashville, TN 37235 (United States); Solouki, Touradj, E-mail: Touradj_Solouki@baylor.edu [Department of Chemistry and Biochemistry, Baylor University, Waco, TX 76798 (United States)

2016-10-05

Ion mobility (IM) is an important analytical technique for determining ion collision cross section (CCS) values in the gas-phase and gaining insight into molecular structures and conformations. However, limited instrument resolving powers for IM may restrict adequate characterization of conformationally similar ions, such as structural isomers, and reduce the accuracy of IM-based CCS calculations. Recently, we introduced an automated technique for extracting “pure” IM and collision-induced dissociation (CID) mass spectra of IM overlapping species using chemometric deconvolution of post-IM/CID mass spectrometry (MS) data [J. Am. Soc. Mass Spectrom., 2014, 25, 1810–1819]. Here we extend those capabilities to demonstrate how extracted IM profiles can be used to calculate accurate CCS values of peptide isomer ions which are not fully resolved by IM. We show that CCS values obtained from deconvoluted IM spectra match with CCS values measured from the individually analyzed corresponding peptides on uniform field IM instrumentation. We introduce an approach that utilizes experimentally determined IM arrival time (AT) “shift factors” to compensate for ion acceleration variations during post-IM/CID and significantly improve the accuracy of the calculated CCS values. Also, we discuss details of this IM deconvolution approach and compare empirical CCS values from traveling wave (TW)IM-MS and drift tube (DT)IM-MS with theoretically calculated CCS values using the projected superposition approximation (PSA). For example, experimentally measured deconvoluted TWIM-MS mean CCS values for doubly-protonated RYGGFM, RMFGYG, MFRYGG, and FRMYGG peptide isomers were 288.{sub 8} Å{sup 2}, 295.{sub 1} Å{sup 2}, 296.{sub 8} Å{sup 2}, and 300.{sub 1} Å{sup 2}; all four of these CCS values were within 1.5% of independently measured DTIM-MS values.

Determination of ion mobility collision cross sections for unresolved isomeric mixtures using tandem mass spectrometry and chemometric deconvolution

International Nuclear Information System (INIS)

Harper, Brett; Neumann, Elizabeth K.; Stow, Sarah M.; May, Jody C.; McLean, John A.; Solouki, Touradj

2016-01-01

Ion mobility (IM) is an important analytical technique for determining ion collision cross section (CCS) values in the gas-phase and gaining insight into molecular structures and conformations. However, limited instrument resolving powers for IM may restrict adequate characterization of conformationally similar ions, such as structural isomers, and reduce the accuracy of IM-based CCS calculations. Recently, we introduced an automated technique for extracting “pure” IM and collision-induced dissociation (CID) mass spectra of IM overlapping species using chemometric deconvolution of post-IM/CID mass spectrometry (MS) data [J. Am. Soc. Mass Spectrom., 2014, 25, 1810–1819]. Here we extend those capabilities to demonstrate how extracted IM profiles can be used to calculate accurate CCS values of peptide isomer ions which are not fully resolved by IM. We show that CCS values obtained from deconvoluted IM spectra match with CCS values measured from the individually analyzed corresponding peptides on uniform field IM instrumentation. We introduce an approach that utilizes experimentally determined IM arrival time (AT) “shift factors” to compensate for ion acceleration variations during post-IM/CID and significantly improve the accuracy of the calculated CCS values. Also, we discuss details of this IM deconvolution approach and compare empirical CCS values from traveling wave (TW)IM-MS and drift tube (DT)IM-MS with theoretically calculated CCS values using the projected superposition approximation (PSA). For example, experimentally measured deconvoluted TWIM-MS mean CCS values for doubly-protonated RYGGFM, RMFGYG, MFRYGG, and FRMYGG peptide isomers were 288._8 Å"2, 295._1 Å"2, 296._8 Å"2, and 300._1 Å"2; all four of these CCS values were within 1.5% of independently measured DTIM-MS values.

Online Ozonolysis Combined with Ion Mobility-Mass Spectrometry Provides a New Platform for Lipid Isomer Analyses

Energy Technology Data Exchange (ETDEWEB)

Poad, Berwyck L.; Zheng, Xueyun; Mitchell, Todd A.; Smith, Richard D.; Baker, Erin M.; Blanksby, Stephen J.

2017-12-21

One of the most significant challenges in contemporary lipidomics lies in the separation and identification of lipid isomers that differ only in site(s) of unsaturation or geometric configuration of the carbon-carbon double bonds. While analytical separation techniques including ion mobility spectrometry (IMS) and liquid chromatography (LC) can separate isomeric lipids under appropriate conditions, conventional tandem mass spectrometry cannot provide unequivocal identification. To address this challenge, we have implemented ozone-induced dissociation (OzID) in-line with LC, IMS and high resolution mass spectrometry. Modification of an IMS- capable quadrupole time-of-flight mass spectrometer was undertaken to allow the introduction of ozone into the high-pressure trapping ion funnel region preceding the IMS cell. This enabled the novel LC-OzID-IMS-MS configuration where ozonolysis of ionized lipids occurred rapidly (10 ms) without prior mass-selection. LC-elution time alignment combined with accurate mass and arrival time extraction of ozonolysis products facilitated correlation of precursor and product ions without mass-selection (and associated reductions in duty cycle). Unsaturated lipids across 11 classes were examined using this workflow in both positive and negative ion modalities and in all cases the positions of carbon-carbon double bonds were unequivocally assigned based on predictable OzID transitions. Under these conditions geometric isomers exhibited different IMS arrival time distributions and distinct OzID product ion ratios providing a means for discrimination of cis/trans double bonds in complex lipids. The combination of OzID with multidimensional separations shows significant promise for facile profiling of unsaturation patterns within complex lipidomes.

New mass analysis and results for neutron rich nuclei performed with isochronous mass spectrometry

Energy Technology Data Exchange (ETDEWEB)

Diwisch, Marcel [Justus-Liebig-Universitaet Giessen, Giessen (Germany); Knoebel, Ronja; Geissel, Hans; Plass, Wolfgang; Scheidenberger, Christoph [Justus-Liebig-Universitaet Giessen, Giessen (Germany); GSI Helmholtzzentrum fuer Schwerionenforschung, Darmstadt (Germany); Patyk, Zygmunt [Soltan Institute for Nuclear Studies, Warsaw (Poland); Weick, Helmut [GSI Helmholtzzentrum fuer Schwerionenforschung, Darmstadt (Germany)

2015-07-01

The Isochronous Mass Spectrometry (IMS) allows to measure masses of rare exotic nuclei in a storage ring in a timescale of tens of μs. The ring is operated in an isochronous mode, i.e. such that particles with different velocities but same mass-to-charge ratio (m/q) travel different paths in the ring arcs (faster ions travel longer paths whereas slower ions travel shorter paths). This means that for each m/q a fix revolution time exists and can be measured by a time-of-flight (TOF) detector which then yields the masses of the nuclei for known charge states. A new analysis approach of IMS data with a correlation matrix method allowed combining data with different quality. The latest production run was using an additional determination of the magnetic rigidity which increased the resolving power of the experiment. Combining this experiment with previous experiments one can increase the statistics and accuracy of the overall mass determination. It was possible to deduce mass values of neutron rich isotopes which have not been measured before. One of those isotopes is {sup 130}Cd which is a very important nuclei involved in the r-process. Those mass values and a comparison to theoretical predictions will be presented in the poster.

INTERMEDIATE-MASS HOT CORES AT ∼500 AU: DISKS OR OUTFLOWS?

International Nuclear Information System (INIS)

Palau, Aina; Girart, Josep M.; Fuente, Asunción; Alonso-Albi, Tomás; Fontani, Francesco; Sánchez-Monge, Álvaro; Boissier, Jérémie; Piétu, Vincent; Neri, Roberto; Busquet, Gemma; Estalella, Robert; Zapata, Luis A.; Zhang, Qizhou; Ho, Paul T. P.; Audard, Marc

2011-01-01

Observations with the Plateau de Bure Interferometer in the most extended configuration toward two intermediate-mass star-forming regions, IRAS 22198+6336 and AFGL 5142, reveal the presence of several complex organic molecules at ∼500 AU scales, confirming the presence of hot cores in both regions. The hot cores are not rich in CN-bearing molecules, as often seen in massive hot cores, and are mainly traced by CH 3 CH 2 OH, (CH 2 OH) 2 , CH 3 COCH 3 , and CH 3 OH, with, additionally, CH 3 CHO, CH 3 OD, and HCOOD for IRAS 22198+6336, and C 6 H and O 13 CS for AFGL 5142. The emission of complex molecules is resolved down to sizes of ∼300 and ∼600 AU, for IRAS 22198+6336 and AFGL 5142, respectively, and most likely is tracing protostellar disks rather than flattened envelopes or toroids as is usually found. This is especially clear for the case of IRAS 22198+6336, where we detect a velocity gradient for all the mapped molecules perpendicular to the most chemically rich outflow of the region, yielding a dynamic mass ∼> 4 M ☉ . As for AFGL 5142, the hot core emission is resolved into two elongated cores separated ∼1800 AU. A detailed comparison of the complex molecule peaks to the new CO (2-1) data and H 2 O maser data from the literature suggests also that for AFGL 5142 the complex molecules are mainly associated with disks, except for a faint and extended molecular emission found to the west, which is possibly produced in the interface between one of the outflows and the dense surrounding gas.

Identification of combustion intermediates in low-pressure premixed pyridine/oxygen/argon flames.

Science.gov (United States)

Tian, Zhenyu; Li, Yuyang; Zhang, Taichang; Zhu, Aiguo; Qi, Fei

2008-12-25

Combustion intermediates of two low-pressure premixed pyridine/oxygen flames with respective equivalence ratios of 0.56 (C/O/N = 1:4.83:0.20) and 2.10 (C/O/N = 1:1.29:0.20) have been identified with tunable synchrotron vacuum ultraviolet (VUV) photoionization and molecular-beam mass spectrometry techniques. About 80 intermediates in the rich flame and 60 intermediates in the lean flame, including nitrogenous, oxygenated, and hydrocarbon intermediates, have been identified by measurements of photoionization mass spectra and photoionization efficiency spectra. Some radicals and new nitrogenous intermediates are identified in the present work. The experimental results are useful for studying the conversion of volatile nitrogen compounds and understanding the formation mechanism of NO(x) in flames of nitrogenous fuels.

Synthesis and DNA binding properties of 1-(3-aminopropyl)-imidazole-containing triamide f-Im*PyIm: a novel diamino polyamide designed to target 5'-ACGCGT-3'.

Science.gov (United States)

Satam, Vijay; Babu, Balaji; Porte, Alexander; Savagian, Mia; Lee, Megan; Smeltzer, Thomas; Liu, Yang; Ramos, Joseph; Wilson, W David; Lin, Shicai; Kiakos, Kostantinos; Hartley, John A; Lee, Moses

2012-09-15

A novel diamino/dicationic polyamide f-Im(*)PyIm (5) that contains an orthogonally positioned aminopropyl chain on an imidazole (Im(*)) moiety was designed to target 5'-ACGCGT-3'. The DNA binding properties of the diamino polyamide 5, determined by CD, ΔT(M), DNase I footprinting, SPR, and ITC studies, were compared with those of its monoamino/monocationic counterpart f-ImPyIm (1) and its diamino/dicationic isomer f-ImPy(*)Im (2), which has the aminopropyl group attached to the central pyrrole unit (Py(*)). The results gave evidence for the minor groove binding and selectivity of polyamide 5 for the cognate sequence 5'-ACGCGT-3', and with strong affinity (K(eq)=2.3×10(7) M(-1)). However, the binding affinities varied according to the order: f-ImPy(*)Im (2)>f-ImPyIm (1)≥f-Im(*)PyIm (5) confirming that the second amino group can improve affinity, but its position within the polyamide can affect affinity. Copyright © 2012 Elsevier Ltd. All rights reserved.

INTERMEDIATE-MASS HOT CORES AT {approx}500 AU: DISKS OR OUTFLOWS?

Energy Technology Data Exchange (ETDEWEB)

Palau, Aina; Girart, Josep M. [Institut de Ciencies de l' Espai (CSIC-IEEC), Campus UAB-Facultat de Ciencies, Torre C5-parell 2, 08193 Bellaterra, Catalunya (Spain); Fuente, Asuncion; Alonso-Albi, Tomas [Observatorio Astronomico Nacional, P.O. Box 112, 28803 Alcala de Henares, Madrid (Spain); Fontani, Francesco; Sanchez-Monge, Alvaro [Osservatorio Astrofisico di Arcetri, INAF, Largo E. Fermi 5, 50125 Firenze (Italy); Boissier, Jeremie [Istituto di Radioastronomia, INAF, Via Gobetti 101, Bologna (Italy); Pietu, Vincent; Neri, Roberto [IRAM, 300 Rue de la piscine, 38406 Saint Martin d' Heres (France); Busquet, Gemma [Istituto di Fisica dello Spazio Interplanetario, INAF, Area di Recerca di Tor Vergata, Via Fosso Cavaliere 100, 00133 Roma (Italy); Estalella, Robert [Departament d' Astronomia i Meteorologia (IEEC-UB), Institut Ciencies Cosmos, Universitat Barcelona, Marti Franques 1, 08028 Barcelona (Spain); Zapata, Luis A. [Centro de Radioastronomia y Astrofisica, Universidad Nacional Autonoma de Mexico, P.O. Box 3-72, 58090 Morelia, Michoacan (Mexico); Zhang, Qizhou; Ho, Paul T. P. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Audard, Marc, E-mail: palau@ieec.uab.es [Geneva Observatory, University of Geneva, Ch. des Maillettes 51, 1290 Versoix (Switzerland)

2011-12-20

Observations with the Plateau de Bure Interferometer in the most extended configuration toward two intermediate-mass star-forming regions, IRAS 22198+6336 and AFGL 5142, reveal the presence of several complex organic molecules at {approx}500 AU scales, confirming the presence of hot cores in both regions. The hot cores are not rich in CN-bearing molecules, as often seen in massive hot cores, and are mainly traced by CH{sub 3}CH{sub 2}OH, (CH{sub 2}OH){sub 2}, CH{sub 3}COCH{sub 3}, and CH{sub 3}OH, with, additionally, CH{sub 3}CHO, CH{sub 3}OD, and HCOOD for IRAS 22198+6336, and C{sub 6}H and O{sup 13}CS for AFGL 5142. The emission of complex molecules is resolved down to sizes of {approx}300 and {approx}600 AU, for IRAS 22198+6336 and AFGL 5142, respectively, and most likely is tracing protostellar disks rather than flattened envelopes or toroids as is usually found. This is especially clear for the case of IRAS 22198+6336, where we detect a velocity gradient for all the mapped molecules perpendicular to the most chemically rich outflow of the region, yielding a dynamic mass {approx}> 4 M{sub Sun }. As for AFGL 5142, the hot core emission is resolved into two elongated cores separated {approx}1800 AU. A detailed comparison of the complex molecule peaks to the new CO (2-1) data and H{sub 2}O maser data from the literature suggests also that for AFGL 5142 the complex molecules are mainly associated with disks, except for a faint and extended molecular emission found to the west, which is possibly produced in the interface between one of the outflows and the dense surrounding gas.

Chemical Abundances of Main-sequence, Turnoff, Subgiant, and Red Giant Stars from APOGEE Spectra. I. Signatures of Diffusion in the Open Cluster M67

Science.gov (United States)

Souto, Diogo; Cunha, Katia; Smith, Verne V.; Allende Prieto, C.; García-Hernández, D. A.; Pinsonneault, Marc; Holzer, Parker; Frinchaboy, Peter; Holtzman, Jon; Johnson, J. A.; Jönsson, Henrik; Majewski, Steven R.; Shetrone, Matthew; Sobeck, Jennifer; Stringfellow, Guy; Teske, Johanna; Zamora, Olga; Zasowski, Gail; Carrera, Ricardo; Stassun, Keivan; Fernandez-Trincado, J. G.; Villanova, Sandro; Minniti, Dante; Santana, Felipe

2018-04-01

Detailed chemical abundance distributions for 14 elements are derived for eight high-probability stellar members of the solar metallicity old open cluster M67 with an age of ∼4 Gyr. The eight stars consist of four pairs, with each pair occupying a distinct phase of stellar evolution: two G dwarfs, two turnoff stars, two G subgiants, and two red clump (RC) K giants. The abundance analysis uses near-IR high-resolution spectra (λ1.5–1.7 μm) from the Apache Point Observatory Galactic Evolution Experiment survey and derives abundances for C, N, O, Na, Mg, Al, Si, K, Ca, Ti, V, Cr, Mn, and Fe. Our derived stellar parameters and metallicity for 2M08510076+1153115 suggest that this star is a solar twin, exhibiting abundance differences relative to the Sun of ≤0.04 dex for all elements. Chemical homogeneity is found within each class of stars (∼0.02 dex), while significant abundance variations (∼0.05–0.20 dex) are found across the different evolutionary phases; the turnoff stars typically have the lowest abundances, while the RCs tend to have the largest. Non-LTE corrections to the LTE-derived abundances are unlikely to explain the differences. A detailed comparison of the derived Fe, Mg, Si, and Ca abundances with recently published surface abundances from stellar models that include chemical diffusion provides a good match between the observed and predicted abundances as a function of stellar mass. Such agreement would indicate the detection of chemical diffusion processes in the stellar members of M67.

High Spatial Resolution Imaging Mass Spectrometry of Human Optic Nerve Lipids and Proteins

Science.gov (United States)

Anderson, David M. G.; Spraggins, Jeffrey M.; Rose, Kristie L.; Schey, Kevin L.

2015-06-01

The human optic nerve carries signals from the retina to the visual cortex of the brain. Each optic nerve is comprised of approximately one million nerve fibers that are organized into bundles of 800-1200 fibers surrounded by connective tissue and supportive glial cells. Damage to the optic nerve contributes to a number of blinding diseases including: glaucoma, neuromyelitis optica, optic neuritis, and neurofibromatosis; however, the molecular mechanisms of optic nerve damage and death are incompletely understood. Herein we present high spatial resolution MALDI imaging mass spectrometry (IMS) analysis of lipids and proteins to define the molecular anatomy of the human optic nerve. The localization of a number of lipids was observed in discrete anatomical regions corresponding to myelinated and unmyelinated nerve regions as well as to supporting connective tissue, glial cells, and blood vessels. A protein fragment from vimentin, a known intermediate filament marker for astrocytes, was observed surrounding nerved fiber bundles in the lamina cribrosa region. S100B was also found in supporting glial cell regions in the prelaminar region, and the hemoglobin alpha subunit was observed in blood vessel areas. The molecular anatomy of the optic nerve defined by MALDI IMS provides a firm foundation to study biochemical changes in blinding human diseases.

Application of ion mobility-mass spectrometry to microRNA analysis.

Science.gov (United States)

Takebayashi, Kosuke; Hirose, Kenji; Izumi, Yoshihiro; Bamba, Takeshi; Fukusaki, Eiichiro

2013-03-01

Liquid chromatography/mass spectrometry is widely used for studying sequence determination and modification analysis of small RNAs. However, the efficiency of liquid chromatography-based separation of intact small RNA species is insufficient, since the physiochemical properties among small RNAs are very similar. In this study, we focused on ion mobility-mass spectrometry (IM-MS), which is a gas-phase separation technique coupled with mass spectrometry; we have evaluated the utility of IM-MS for microRNA (miRNA) analysis. A multiply charged deprotonated ion derived from an 18-24-nt-long miRNA was formed by electrospray ionization, and then the time, called the "drift time", taken by each ion to migrate through a buffer gas was measured. Each multivalent ion was temporally separated on the basis of the charge state and structural formation; 3 types of unique mass-mobility correlation patterns (i.e., chainlike-form, hairpin-form, and dimer-form) were present on the two-dimensional mobility-mass spectrum. Moreover, we found that the ion size (sequence length) and the secondary structures of the small RNAs strongly contributed to the IM-MS-based separation, although solvent conditions such as pH had no effect. Therefore, sequence isomers could also be discerned by the selection of each specific charged ion, i.e., the 6(-) charged ion reflected a majority among chainlike-, hairpin-, and other structures. We concluded that the IM-MS provides additional capability for separation; thus, this analytical method will be a powerful tool for comprehensive small RNA analysis. Copyright © 2012. Published by Elsevier B.V.

A Tidal Disruption Event in a Nearby Galaxy Hosting an Intermediate Mass Black Hole

Science.gov (United States)

Donato, D; Cenko, S. B.; Covino, S.; Troja, E.; Pursimo, T.; Cheung, C. C.; Fox, O.; Kutyrev, A.; Campana, S.; Fugazza, D.;

A New IMS Based Inter-working Solution

Science.gov (United States)

Zhu, Zhongwen; Brunner, Richard

With the evolution of third generation network, more and more multimedia services are developed and deployed. Any new service to be deployed in IMS network is required to inter-work with existing Internet communities or legacy terminal users in order to appreciate the end users, who are the main drivers for the service to succeed. The challenge for Inter-working between IMS (IP Multimedia Subsystem) and non-IMS network is “how to handle recipient’s address”. This is because each network has its own routable address schema. For instance, the address for Google Talk user is xmpp:xyz@google.com, which is un-routable in IMS network. Hereafter a new Inter-working (IW) solution between IMS and non-IMS network is proposed for multimedia services that include Instant Messaging, Chat, and File transfer, etc. It is an end-to-end solution built on IMS infrastructure. The Public Service Identity (PSI) defined in 3GPP standard (3rd Generation Partnership Project) is used to allow terminal clients to allocate this IW service. When sending the SIP (Session Initial Protocol) request out for multimedia services, the terminal includes the recipient’s address in the payload instead of the “Request-URI” header. In the network, the proposed solution provides the mapping rules between different networks in MM-IW (Multimedia IW). The detailed technical description and the corresponding use cases are present. The comparison with other alternatives is made. The benefits of the proposed solution are highlighted.

MALDI Imaging Mass Spectrometry (MALDI-IMS―Application of Spatial Proteomics for Ovarian Cancer Classification and Diagnosis

Directory of Open Access Journals (Sweden)

Johan O. R. Gustafsson

2011-01-01

Full Text Available MALDI imaging mass spectrometry (MALDI-IMS allows acquisition of mass data for metabolites, lipids, peptides and proteins directly from tissue sections. IMS is typically performed either as a multiple spot profiling experiment to generate tissue specific mass profiles, or a high resolution imaging experiment where relative spatial abundance for potentially hundreds of analytes across virtually any tissue section can be measured. Crucially, imaging can be achieved without prior knowledge of tissue composition and without the use of antibodies. In effect MALDI-IMS allows generation of molecular data which complement and expand upon the information provided by histology including immuno-histochemistry, making its application valuable to both cancer biomarker research and diagnostics. The current state of MALDI-IMS, key biological applications to ovarian cancer research and practical considerations for analysis of peptides and proteins on ovarian tissue are presented in this review.

Argumentellipse in der "weichen" Nachricht im Deutschen und im Slowenischen

Directory of Open Access Journals (Sweden)

Uršula Krevs

1998-12-01

Full Text Available Argumentellipsen werden in der sprachlichen Kommunikation ohne weiteres akzeptiert, obwohl sie allenfalls in gewissem Sinne wegen ihrer Elliptizität abweichend wirken. Im folgenden interessiert uns, wie die Argumentellipse als syntaktische Entität in den Text eingebettet wird und welche Funktionen sie ausübt. Unsere Aufmerksamkeit gilt bier der Textsorte "weiche" Nachricht, die als Abweichung des Grundmusters gilt. Um im Sprachenpaar Deutsch-Slowenisch die in dieser Textsorte realisierten Argumentellipsen vergleichen zu können, wurde die Homogenität in der Thematik angestrebt und die Texte aus dem gleichen Kommunikationsbereich gewählt. So wurden die Korpora zwei Zeitschriften, die sich mit der gleichen Sportart beschäftigen, entnommen: der deutschen Zeitschrift "Rotpunkt" und der slowenischen Zeitschrift  "Grif '.

Bifurcations and Chaos of AN Immersed Cantilever Beam in a Fluid and Carrying AN Intermediate Mass

Science.gov (United States)

AL-QAISIA, A. A.; HAMDAN, M. N.

2002-06-01

The concern of this work is the local stability and period-doubling bifurcations of the response to a transverse harmonic excitation of a slender cantilever beam partially immersed in a fluid and carrying an intermediate lumped mass. The unimodal form of the non-linear dynamic model describing the beam-mass in-plane large-amplitude flexural vibration, which accounts for axial inertia, non-linear curvature and inextensibility condition, developed in Al-Qaisia et al. (2000Shock and Vibration7 , 179-194), is analyzed and studied for the resonance responses of the first three modes of vibration, using two-term harmonic balance method. Then a consistent second order stability analysis of the associated linearized variational equation is carried out using approximate methods to predict the zones of symmetry breaking leading to period-doubling bifurcation and chaos on the resonance response curves. The results of the present work are verified for selected physical system parameters by numerical simulations using methods of the qualitative theory, and good agreement was obtained between the analytical and numerical results. Also, analytical prediction of the period-doubling bifurcation and chaos boundaries obtained using a period-doubling bifurcation criterion proposed in Al-Qaisia and Hamdan (2001 Journal of Sound and Vibration244, 453-479) are compared with those of computer simulations. In addition, results of the effect of fluid density, fluid depth, mass ratio, mass position and damping on the period-doubling bifurcation diagrams are studies and presented.

Deep learning for tumor classification in imaging mass spectrometry.

Science.gov (United States)

Behrmann, Jens; Etmann, Christian; Boskamp, Tobias; Casadonte, Rita; Kriegsmann, Jörg; Maaß, Peter

2018-04-01

Tumor classification using imaging mass spectrometry (IMS) data has a high potential for future applications in pathology. Due to the complexity and size of the data, automated feature extraction and classification steps are required to fully process the data. Since mass spectra exhibit certain structural similarities to image data, deep learning may offer a promising strategy for classification of IMS data as it has been successfully applied to image classification. Methodologically, we propose an adapted architecture based on deep convolutional networks to handle the characteristics of mass spectrometry data, as well as a strategy to interpret the learned model in the spectral domain based on a sensitivity analysis. The proposed methods are evaluated on two algorithmically challenging tumor classification tasks and compared to a baseline approach. Competitiveness of the proposed methods is shown on both tasks by studying the performance via cross-validation. Moreover, the learned models are analyzed by the proposed sensitivity analysis revealing biologically plausible effects as well as confounding factors of the considered tasks. Thus, this study may serve as a starting point for further development of deep learning approaches in IMS classification tasks. https://gitlab.informatik.uni-bremen.de/digipath/Deep_Learning_for_Tumor_Classification_in_IMS. jbehrmann@uni-bremen.de or christianetmann@uni-bremen.de. Supplementary data are available at Bioinformatics online.

Intermediate coupling vibrational descriptions of odd mass gold isotopes

CERN Document Server

Vieu, C; Paar, V

1976-01-01

The theoretical analysis of /sup 193-195/Au levels is semi qualitatively performed in the frame of the intermediate coupling vibrational models of Kisslinger-Sorensen and Alaga. From the comparison between the experimental data and the corresponding predictions of the two models, conclusions are drawn on the influence of the clusters and broken pairs.

Identification of ortho-Substituted Benzoic Acid/Ester Derivatives via the Gas-Phase Neighboring Group Participation Effect in (+)-ESI High Resolution Mass Spectrometry.

Science.gov (United States)

Blincoe, William D; Rodriguez-Granillo, Agustina; Saurí, Josep; Pierson, Nicholas A; Joyce, Leo A; Mangion, Ian; Sheng, Huaming

2018-04-01

Benzoic acid/ester/amide derivatives are common moieties in pharmaceutical compounds and present a challenge in positional isomer identification by traditional tandem mass spectrometric analysis. A method is presented for exploiting the gas-phase neighboring group participation (NGP) effect to differentiate ortho-substituted benzoic acid/ester derivatives with high resolution mass spectrometry (HRMS 1 ). Significant water/alcohol loss (>30% abundance in MS 1 spectra) was observed for ortho-substituted nucleophilic groups; these fragment peaks are not observable for the corresponding para and meta-substituted analogs. Experiments were also extended to the analysis of two intermediates in the synthesis of suvorexant (Belsomra) with additional analysis conducted with nuclear magnetic resonance (NMR), density functional theory (DFT), and ion mobility spectrometry-mass spectrometry (IMS-MS) studies. Significant water/alcohol loss was also observed for 1-substituted 1, 2, 3-triazoles but not for the isomeric 2-substituted 1, 2, 3-triazole analogs. IMS-MS, NMR, and DFT studies were conducted to show that the preferred orientation of the 2-substituted triazole rotamer was away from the electrophilic center of the reaction, whereas the 1-subtituted triazole was oriented in close proximity to the center. Abundance of NGP product was determined to be a product of three factors: (1) proton affinity of the nucleophilic group; (2) steric impact of the nucleophile; and (3) proximity of the nucleophile to carboxylic acid/ester functional groups. Graphical Abstract ᅟ.

Fine structural survey of the intermediate subnucleus of the nucleus tractus solitarii and its glossopharyngeal afferent terminals.

Science.gov (United States)

Hayakawa, Tetsu; Maeda, Seishi; Tanaka, Koichi; Seki, Makoto

2005-10-01

The intermediate subnucleus of the nucleus tractus solitarii (imNTS) receives somatosensory inputs from the soft palate and pharynx, and projects onto the nucleus ambiguus, thus serving as a relay nucleus for swallowing. The ultrastructure and synaptology of the rat imNTS, and its glossopharyngeal afferent terminals, have been examined with cholera toxin-conjugated horseradish peroxidase (CT-HRP) as an anterograde tracer. The imNTS contained oval or ellipsoid-shaped, small to medium-sized neurons (18.2 x 11.4 microm) with little cytoplasm, few cell organelles and an irregularly shaped nucleus. The cytoplasm often contained one or two nucleolus-like stigmoid bodies. The average number of axosomatic terminals was 1.8 per profile. About 83% of them contained round vesicles and formed asymmetric synaptic contacts (Gray's type I), while about 17% contained pleomorphic vesicles and formed symmetric synaptic contacts (Gray's type II). The neuropil contained small or large axodendritic terminals, and about 92% of them were Gray's type I. When CT-HRP was injected into the nodose ganglion, many labeled terminals were found in the imNTS. All anterogradely labeled terminals contacted dendrites but not somata. The labeled terminals were usually large (2.69+/-0.09 mum) and exclusively of Gray's type I. They often contacted more than two dendrites, were covered with glial processes, and formed synaptic glomeruli. A small unlabeled terminal occasionally made an asymmetric synaptic contact with a large labeled terminal. The large glossopharyngeal afferent terminals and the neurons containing stigmoid bodies characterized the imNTS neurons that received pharyngeal afferents.

Introductory Overview of Intermediate-luminosity X-ray Objects

Science.gov (United States)

Colbert, E. J. M.

2001-05-01

Intermediate-luminosity X-ray Objects (IXOs) are defined as compact objects having X-ray luminosities between those of X-ray binaries and low-luminosity AGNs (i.e., 1039.0 erg s-1 < ~ LX [IXOs] < ~ 1041.0 erg s-1). It is not currently known if these objects are intermediate-mass (M ~ 102-104 Msun) black holes accreting near the Eddington limit, near-solar-mass black holes in a super-Eddington state, or are, in some cases, just supermassive black holes accreting at very low rates. However, the first idea has been popularized by recent press coverage. IXOs are quite common (present in about half of spiral galaxies) and are typically found displaced from the optical nucleus, reducing the likelihood that they are low-luminosity AGN. Nearly all of our knowledge of these objects comes from X-ray observations, as observations of optical, NIR and radio counterparts are not widely known. In this session, we will address (1) the phenomenology of the objects, (2) possible geometry and accretion mechanisms for these objects (i.e., are they more similar to black hole X-ray binaries or AGNs), (3) the central black hole masses, and (4) the formation mechanism for these black holes, if they are of intermediate mass. In this talk, I will focus primarily on giving background information of these fascinating objects.

THE M BH-L SPHEROID RELATION AT HIGH AND LOW MASSES, THE QUADRATIC GROWTH OF BLACK HOLES, AND INTERMEDIATE-MASS BLACK HOLE CANDIDATES

International Nuclear Information System (INIS)

Graham, Alister W.; Scott, Nicholas

2013-01-01

From a sample of 72 galaxies with reliable supermassive black hole masses M bh , we derive the M bh -(host spheroid luminosity, L) relation for (1) the subsample of 24 core-Sérsic galaxies with partially depleted cores, and (2) the remaining subsample of 48 Sérsic galaxies. Using K s -band Two Micron All Sky Survey data, we find the near-linear relation M bh ∝L 1.10±0.20 K s for the core-Sérsic spheroids thought to be built in additive dry merger events, while we find the relation M bh ∝L 2.73±0.55 K s for the Sérsic spheroids built from gas-rich processes. After converting literature B-band disk galaxy magnitudes into inclination- and dust-corrected bulge magnitudes, via a useful new equation presented herein, we obtain a similar result. Unlike with the M bh -(velocity dispersion) diagram, which is also updated here using the same galaxy sample, it remains unknown whether barred and non-barred Sérsic galaxies are offset from each other in the M bh -L diagram. While black hole feedback has typically been invoked to explain what was previously thought to be a nearly constant M bh /M Spheroid mass ratio of ∼0.2%, we advocate that the near-linear M bh -L and M bh -M Spheroid relations observed at high masses may have instead arisen largely from the additive dry merging of galaxies. We argue that feedback results in a dramatically different scaling relation, such that black hole mass scales roughly quadratically with the spheroid mass in Sérsic galaxies. We therefore introduce a revised cold-gas 'quasar' mode feeding equation for semi-analytical models to reflect what we dub the quadratic growth of black holes in Sérsic galaxies built amidst gas-rich processes. Finally, we use our new Sérsic M bh -L equations to predict the masses of candidate intermediate mass black holes in almost 50 low-luminosity spheroids containing active galactic nuclei, finding many masses between that of stellar mass black holes and supermassive black holes.

IMS Learning Design Frequently Asked Questions

NARCIS (Netherlands)

Tattersall, Colin; Manderveld, Jocelyn; Hummel, Hans; Sloep, Peter; Koper, Rob; De Vries, Fred

2004-01-01

This list of frequently asked questions was composed on the basis of questions asked of the Educational Technology Expertise Centrum. The questions addessed are: Where can I find the IMS Learning Design Specification? What is meant by the phrase “Learning Design”? What is the IMS LD Specification

Resilience of the IMS system

DEFF Research Database (Denmark)

Kamyod, Chayapol; Nielsen, Rasmus Hjorth; Prasad, Neeli R.

2014-01-01

The paper focuses on end-to-end resilience analysis of the IMS based network through the principal resilience parameters by using OPNET. The resilience behaviours of communication across multiple IMS domains are investigated at different communication scenarios and compared with previous state......-of-the-art. Moreover, the resilience effects when adding a redundancy of the S-CSCF unit are examined. The results disclose interesting resilience behaviours for long distance communications....

for the internal rotation evolution of low-mass stars

Directory of Open Access Journals (Sweden)

Pinçon Charly

2017-01-01

Full Text Available Due to the space-borne missions CoRoT and Kepler, noteworthy breakthroughs have been made in our understanding of stellar evolution, and in particular about the angular momentum redistribution in stellar interiors. Indeed, the high-precision seismic data provide with the measurement of the mean core rotation rate for thousands of low-mass stars from the subgiant branch to the red giant branch. All these observations exhibit much lower core rotation rates than expected by current stellar evolution codes and they emphasize the need for an additional transport process. In this framework, internal gravity waves (herefater, IGW could play a signifivative role since they are known to be able to transport angular momentum. In this work, we estimate the effciency of the transport by the IGW that are generated by penetrative convection at the interface between the convective and the radiative regions. As a first step, this study is based on the comparison between the timescale for the waves to modify a given rotation profile and the contraction/expansion timescale throughout the radiative zone of 1.3M⊙ stellar models. We show that IGW, on their own, are ineffcient to slow down the core rotation of stars on the red giant branch, where the radiative damping becomes strong enough and prevent the IGW from reaching the innermost layers. However, we find that IGW generated by penetrative convection could effciently modify the core rotation of subgiant stars as soon as the amplitude of the radial differential rotation between the core and the base of the convective zone is high enough, with typical values close to the observed rotation rates in these stars. This result argues for the necessity to account for IGW generated by penetrative convection in stellar modeling and in the angular momentum redistribution issue.

Prompt emission from tidal disruptions of white dwarfs by intermediate mass black holes

Directory of Open Access Journals (Sweden)

Laguna P.

2012-12-01

Full Text Available We present a qualitative picture of prompt emission from tidal disruptions of white dwarfs (WD by intermediate mass black holes (IMBH. The smaller size of an IMBH compared to a supermassive black hole and a smaller tidal radius of a WD disruption lead to a very fast event with high peak luminosity. Magnetic field is generated in situ following the tidal disruption, which leads to effective accretion. Since large-scale magnetic field is also produced, geometrically thick super-Eddington inflow leads to a relativistic jet. The dense jet possesses a photosphere, which emits quasi-thermal radiation in soft X-rays. The source can be classified as a long low-luminosity gamma-ray burst (ll-GRB. Tidal compression of a WD causes nuclear ignition, which is observable as an accompanying supernova. We suggest that GRB060218 and SN2006aj is such a pair of ll-GRB and supernova. We argue that in a flux-limited sample the disruptions of WDs by IMBHs are more frequent then the disruptions of other stars by IMBHs.

Individualisierte Produkte im Fokus der intergrierten Produktentwicklung

OpenAIRE

Baumberger, C.;Gahr, A.

2017-01-01

Individualisierte Produkte stellen neue Herausforderungen an die Produktentwicklung – vornehmlich im Bereich der Produktstrukturplanung, der kundenindividuellen Produktadaption und dem Zielkostenmanagement. Diese Themen werden am Lehrstuhl für Produktentwicklung im Rahmen des Sonderforschungsbereiches 582 behandelt.

Multi-Reflection Time-of-Flight Mass Separation and Spectrometry

CERN Document Server

Kreim, Susanne; Wolf, R N

2014-01-01

The mass of a nucleus is one of its most fundamental ground-state properties and reveals the strength of nuclear binding. Investigating the binding energy of nuclei with respect to the number of protons and neutrons in a nucleus is important for advancing nuclear theory and increases our understanding of nucleosynthesis in supernovae and neutron stars. Precision mass measurements on radioactive nuclides belong to the state-of-the-art techniques [1, 2]. Presently, four complementary techniques are applied: isochronous and Schottky mass spectrometry in storage rings (IMS and SMS, respectively), magnetic-rigidity time-of-flight (TOF-ρ) measurements, and Penning-trap mass spectrometry (PTMS). With measurement cycles in the sub-ms range, IMS and TOF-Bρ MS are well suited for very short-lived species while offering moderate relative precision on the level of 10−6. A higher precision is achieved by SMS but with the need for measurement times on the order of several seconds. As soon as masses with a relative prec...

Managing P2P services via the IMS

NARCIS (Netherlands)

Liotta, A.; Lin, L.

2007-01-01

The key aim of our work was to illustrate the benefits and means to deploy P2P services via the IMS. Having demonstrated the technical viability of P2P-IMS we have also found a way to add a new management dimension to existing P2P systems. P2P-IMS comes with a natural "data management" mechanism,

Geschlechterstereotype im Einsatz

Directory of Open Access Journals (Sweden)

Erika Kegyes

2007-11-01

Full Text Available Die umfangreiche Monographie gehört zum Forschungsbereich der kritischen angewandten Linguistik (Critical Applied Linguistics und liegt sowohl theoretisch als auch praktisch im Schnittpunkt der gender- und werbesprachlichen Untersuchungen.

Intermediate L-K molecular orbital radiation from heavy ion collisions

International Nuclear Information System (INIS)

Heinig, K.H.; Jaeger, H.U.; Richter, H.; Woittennek, H.

1975-09-01

The structure of x-ray continua observed recently in violent collisions between intermediate mass atoms can be explained by a superposition of K molecular orbital (KMO) radiation and of an intermediate L-K molecular orbital (ILKMO) radiation of high intensity which is due to 2psigma vacancies. (author)

Muriithi, IM

African Journals Online (AJOL)

Muriithi, IM. Vol 8, No 2 (2014) - Articles Correlation of magnetic resonance imaging findings with arthroscopy in the evaluation of rotator cuff pathology. Abstract PDF · Vol 8, No 2 (2014) - Articles Patterns of knee, hip and hand osteoarthritis in Kenyatta National Hospital Abstract PDF. ISSN: 1994-1072. AJOL African ...

Wandering off the centre: a characterization of the random motion of intermediate-mass black holes in star clusters

Science.gov (United States)

de Vita, Ruggero; Trenti, Michele; MacLeod, Morgan

2018-04-01

Despite recent observational efforts, unequivocal signs for the presence of intermediate-mass black holes (IMBHs) in globular clusters (GCs) have not been found yet. Especially when the presence of IMBHs is constrained through dynamical modelling of stellar kinematics, it is fundamental to account for the displacement that the IMBH might have with respect to the GC centre. In this paper, we analyse the IMBH wandering around the stellar density centre using a set of realistic direct N-body simulations of star cluster evolution. Guided by the simulation results, we develop a basic yet accurate model that can be used to estimate the average IMBH radial displacement (〈rbh〉) in terms of structural quantities as the core radius (rc), mass (Mc), and velocity dispersion (σc), in addition to the average stellar mass (mc) and the IMBH mass (Mbh). The model can be expressed by the equation /r_c=A(m_c/M_bh)^α [σ _c^2r_c/(GM_c)]^β, in which the free parameters A, α, and β are calculated through comparison with the numerical results on the IMBH displacement. The model is then applied to Galactic GCs, finding that for an IMBH mass equal to 0.1 per cent of the GC mass, the typical expected displacement of a putative IMBH is around 1 arcsec for most Galactic GCs, but IMBHs can wander to larger angular distances in some objects, including a prediction of a 2.5 arcsec displacement for NGC 5139 (ω Cen), and >10 arcsec for NGC5053, NGC6366, and ARP2.

Ion Mobility Mass Spectrometry Direct Isotope Abundance Analysis

International Nuclear Information System (INIS)

Manard, Manuel J.; Weeks, Stephan; Kyle, Kevin

2010-01-01

The nuclear forensics community is currently engaged in the analysis of illicit nuclear or radioactive material for the purposes of non-proliferations and attribution. One technique commonly employed for gathering nuclear forensics information is isotope analysis. At present, the state-of-the-art methodology for obtaining isotopic distributions is thermal ionization mass spectrometry (TIMS). Although TIMS is highly accurate at determining isotope distributions, the technique requires an elementally pure sample to perform the measurement. The required radiochemical separations give rise to sample preparation times that can be in excess of one to two weeks. Clearly, the nuclear forensics community is in need of instrumentation and methods that can expedite their decision making process in the event of a radiological release or nuclear detonation. Accordingly, we are developing instrumentation that couples a high resolution IM drift cell to the front end of a MS. The IM cell provides a means of separating ions based upon their collision cross-section and mass-to-charge ratio (m/z). Two analytes with the same m/z, but with different collision cross-sections (shapes) would exit the cell at different times, essentially enabling the cell to function in a similar manner to a gas chromatography (GC) column. Thus, molecular and atomic isobaric interferences can be effectively removed from the ion beam. The mobility selected chemical species could then be introduced to a MS for high-resolution mass analysis to generate isotopic distributions of the target analytes. The outcome would be an IM/MS system capable of accurately measuring isotopic distributions while concurrently eliminating isobaric interferences and laboratory radiochemical sample preparation. The overall objective of this project is developing instrumentation and methods to produce near real-time isotope distributions with a modular mass spectrometric system that performs the required gas-phase chemistry and

Novel pathway of SO2 oxidation in the atmosphere: reactions with monoterpene ozonolysis intermediates and secondary organic aerosol

Science.gov (United States)

Ye, Jianhuai; Abbatt, Jonathan P. D.; Chan, Arthur W. H.

2018-04-01

Ozonolysis of monoterpenes is an important source of atmospheric biogenic secondary organic aerosol (BSOA). While enhanced BSOA formation has been associated with sulfate-rich conditions, the underlying mechanisms remain poorly understood. In this work, the interactions between SO2 and reactive intermediates from monoterpene ozonolysis were investigated under different humidity conditions (10 % vs. 50 %). Chamber experiments were conducted with ozonolysis of α-pinene or limonene in the presence of SO2. Limonene SOA formation was enhanced in the presence of SO2, while no significant changes in SOA yields were observed during α-pinene ozonolysis. Under dry conditions, SO2 primarily reacted with stabilized Criegee intermediates (sCIs) produced from ozonolysis, but at 50 % RH heterogeneous uptake of SO2 onto organic aerosol was found to be the dominant sink of SO2, likely owing to reactions between SO2 and organic peroxides. This SO2 loss mechanism to organic peroxides in SOA has not previously been identified in experimental chamber studies. Organosulfates were detected and identified using an electrospray ionization-ion mobility spectrometry-high-resolution time-of-flight mass spectrometer (ESI-IMS-TOF) when SO2 was present in the experiments. Our results demonstrate the synergistic effects between BSOA formation and SO2 oxidation through sCI chemistry and SO2 uptake onto organic aerosol and illustrate the importance of considering the chemistry of organic and sulfur-containing compounds holistically to properly account for their reactive sinks.

Bremssysteme im Personenkraftwagen

Science.gov (United States)

Reif, Konrad

Für die ersten drei Punkte ist die Betriebsbremsanlage ("Fußbremse“) zuständig. Der Fahrer aktiviert sie durch Betätigen des Bremspedals. Die Feststellbremsanlage ("Handbremse“) hält das Fahrzeug im Stillstand.

Support interoperability and reusability of emerging forms of assessment: Some issues on integrating IMS LD with IMS QTI

NARCIS (Netherlands)

Miao, Yongwu; Boon, Jo; Van der Klink, Marcel; Sloep, Peter; Koper, Rob

2009-01-01

Miao, Y., Boon, J., Van der Klink, M., Sloep, P. B., & Koper, R. (2011). Support interoperability and reusability of emerging forms of assessment: Some issues on integrating IMS LD with IMS QTI. In F. Lazarinis, S. Green, & E. Pearson (Eds.), E-Learning Standards and Interoperability: Frameworks

Politische Inhalte im Internet: Angebot und Nachfrage politischer Inhalte im World Wide Web am Beispiel von Volksabstimmungen in der Schweiz

OpenAIRE

Rademacher, Patrick Horst Josef

2010-01-01

Welche Bedeutung kommt dem Internet in der Politikvermittlung zu? Dieser Frage geht Patrick Rademacher nach, indem er untersucht, welche Anbieter politische Inhalte im Internet zur Verfügung stellen, wie sie dabei vorgehen und wie die Struktur der Inhalte beschaffen ist. Darüber hinaus analysiert er, inwiefern die online angebotenen Inhalte auf eine Nachfrage durch die Bürger treffen. Im Untersuchungskontext von Volksabstimmungen in der Schweiz hat der Autor hierfür im Jahr 2008 umfangreiche ...

Evaluation of false positive responses by mass spectrometry and ion mobility spectrometry for the detection of trace explosives in complex samples

Energy Technology Data Exchange (ETDEWEB)

Crawford, C.L., E-mail: clcrawf@sandia.gov; Hill, H.H.

2013-09-17

Graphical abstract: -- Highlights: •First study to use (−)SESI-IM-TOFMS to analyze complex mixtures of personal care products. •The study demonstrated, by identifying mobility and mass interferents with explosive signatures, which, if used separately, neither IMS nor MS alone would prevent every false positive for explosives when detected in the presence of a complex sample matrix. •Ingredients in common household cleaning products were shown to either enhance or suppress the ionization of explosives in a SESI-IM-TOFMS analysis. •Mobility separation provided real-time separation of ion species that indicated overlapping isotope peak patterns -- Abstract: Secondary electrospray ionization-ion mobility-time of flight mass spectrometry (SESI-IM-TOFMS) was used to evaluate common household products and food ingredients for any mass or mobility responses that produced false positives for explosives. These products contained ingredients which shared the same mass and mobility drift time ranges as the analyte ions for common explosives. The results of this study showed that the vast array of compounds in these products can cause either mass or mobility false positive responses. This work also found that two ingredients caused either enhanced or reduced ionization of the target analytes. Another result showed that an IMS can provide real-time separation of ion species that impede accurate mass identifications due to overlapping isotope peak patterns. The final result of this study showed that, when mass and mobility values were used to identify an ion, no false responses were found for the target explosives. The wider implication of these results is that the possibility exists for even greater occurrences of false responses from complex mixtures found in common products. Neither IMS nor MS alone can provide 100% assurance from false responses. IMS, due to its low cost, ease of operation, rugged reliability, high sensitivity and tunable selectivity, will remain

Arctic Intermediate Water in the Nordic Seas, 1991-2009

Science.gov (United States)

Jeansson, Emil; Olsen, Are; Jutterström, Sara

2017-10-01

The evolution of the different types of Arctic Intermediate Water (AIW) in the Nordic Seas is evaluated and compared utilising hydro-chemical data from 1991 to 2009. It has been suggested that these waters are important components of the Norwegian Sea Arctic Intermediate Water (NSAIW), and of the dense overflows to the North Atlantic. Thus, it is important to understand how their properties and distribution vary with time. The AIWs from the Greenland and Iceland Seas, show different degrees of variability during the studied period; however, only the Greenland Sea Arctic Intermediate Water (GSAIW) shows an increasing temperature and salinity throughout the 2000s, which considerably changed the properties of this water mass. Optimum multiparameter (OMP) analysis was conducted to assess the sources of the NSAIW. The analysis shows that the Iceland Sea Arctic Intermediate Water (ISAIW) and the GSAIW both contribute to NSAIW, at different densities corresponding to their respective density range. This illustrates that they flow largely isopycnally from their source regions to the Norwegian Sea. The main source of the NSAIW, however, is the upper Polar Deep Water, which explains the lower concentrations of oxygen and chlorofluorocarbons, and higher salinity and nutrient concentrations of the NSAIW layer compared with the ISAIW and GSAIW. This shows how vital it is to include chemical tracers in any water mass analysis to correctly assess the sources of the water mass being studied.

Measurement of Fragment Mass Distributions in Neutron-induced Fission of 238U and 232Th at Intermediate Energies

International Nuclear Information System (INIS)

Simutkin, V.D.

2008-01-01

Conceptual analysis of accelerator-driven systems assumes extensive use of nuclear data on neutron-induced reactions at intermediate energies. In particular, information about the fission fragment yields from the 238 U(n,f) and 232 Th(n,f) reactions is of particular interest at neutron energies from 10 to 200 MeV. However, there is a lack of such data for both 238 U and 232 Th. Up to now, the intermediate energy measurements have been performed for 238 U only, and there are no data for the 232 Th(n,f) reaction. The aim of the work is to provide such data. Fission fragment mass distributions for the 232 Th(n,f) and 238 U(n,f) reactions have been measured for the incident neutron energies 32.8 MeV, 45.3 MeV and 59.9 MeV. The experiments have been performed at the neutron beam facility of the Universite Catholique de Louvain, Belgium. A multi-section Frisch-gridded ionization chamber has been used as a fission fragment detector. The data obtained have been interpreted in terms of the multimodal random neck-rupture model (MMRNRM). (authors)

Gruppenbezogene Menschenfeindlichkeit im Sport in Brandenburg

OpenAIRE

Delto, Hannes; Tzschoppe, Petra

2016-01-01

Mit der Querschnittsstudie "Wir und die Anderen – Gruppenbezogene Menschenfeindlichkeit im organisierten Sport in Brandenburg" wurde das Syndrom Gruppenbezogener Menschenfeindlichkeit im organisierten Sport untersucht. Das Konzept der Gruppenbezogenen Menschenfeindlichkeit – ausgehend von einer Ideologie der Ungleichwertigkeit – wurde von Prof. Wilhelm Heitmeyer (Universität Bielefeld) entwickelt. Die Ergebnisse ermöglichen explizite Aussagen über Ausmaß und Ursachen Gruppenbezogener Menschen...

Verletzungen und Fehlbeanspruchungen im leistungsorientierten Rudersport

OpenAIRE

Bussian, Marc Robert

2004-01-01

Die Stellung der Breitensportart Rudern als gesundheitsfördernde Sportform ist in der Literatur gleichlautend positiv beschrieben. Im leistungsorientierten Rudersport müssen neben den Verletzungen und Fehlbeanspruchungen der eigentlichen Sportart die unabdingbaren Nebentrainingsformen berücksichtigt werden. In den neunziger Jahren vollzog sich ein trainingsmethodischer Wandel, die Einführung eines erschwinglichen Rudersimulators und eine technische Weiterentwicklung im Boots- und Ruderbau. Ei...

Pengaruh Intensitas Mengakses Twitter Duta Im3 terhadap Kepuasan Pengalaman Adopsi dan Kepuasan Pengalaman Adopsi terhadap Keputusan Penggunaan Program Im3

OpenAIRE

Ayu Kinasih, Diyan Hafdinovianti; Pradekso, Tandiyo; Setiabudi, Djoko

2014-01-01

Nama : Diyan H Ayu KinasihNIM : D2C009029Judul : Pengaruh Intensitas Mengakses Twitter Duta IM3 terhadapKepuasan Pengalaman Adopsi dan Kepuasan PengalamanAdopsi terhadap Keputusan Penggunaan Program IM3ABSTRAKTwitter sebagai salah satu promotion tools yang digunakan oleh PTIndosat Tbk, diharapkan dapat memperkenalkan program-program serta eventyang dilakukan oleh Indosat. Melalui duta IM3 sebagai brand ambassador, Indosatmencoba meraih pasar anak muda dengan melakukan kegiatan promosi.Tipe pe...

The Application of Internal Marketing (IM in a Service Organization

Directory of Open Access Journals (Sweden)

R. Sharma

2013-07-01

Findings and Strategic Implications. To complement earlier theoretical proposition on IM, the findings indicate that there are several empirical aspects such as “costs, people and concept” which hinder successful implementation of IM. This study proposes several strategic HR recommendations to reduce the “implementation gap” in IM such as to conduct continuous staff training on IM knowledge on regular time intervals, to reduce excessive work load and pressure and engaging staff members in continuous personal development sessions. In addition, the findings reveal that IM training should be given priority to solve “people-oriented” issues.

Fission of intermediate mass nuclei by bremsstrahlung photons in the energy range 0.8-1.8 GeV

International Nuclear Information System (INIS)

Lima, D.A. de.

1983-01-01

The fission of intermediate mass nuclei in the Al-Ta internal induced by bremsstrahlung photons of maximum energies between 0,8 to 1,8 GeV is studied. Thin targets of Nd and Sm and dense targets of Al,Ti,Co,Zr,Nb,Ag,In and Ta are utilized, and all the aspects related with the fission fragment absorption by the targets themselves are considered. The samples are exposed in th 2,5 GeV Electron Synchrotron at Bonn University. Muscovite mica, CR-39 and makrofol are used as fission fragments detectors. Fission cross sections and nuclear fissionabilities of the studied elements are estimated. (L.C.) [pt

Comprehensive determination of macrolide antibiotics, their synthesis intermediates and transformation products in wastewater effluents and ambient waters by liquid chromatography-tandem mass spectrometry.

Science.gov (United States)

Senta, Ivan; Krizman-Matasic, Ivona; Terzic, Senka; Ahel, Marijan

2017-08-04

Macrolide antibiotics are a prominent group of emerging contaminants frequently found in wastewater effluents and wastewater-impacted aquatic environments. In this work, a novel analytical method for simultaneous determination of parent macrolide antibiotics (azithromycin, erythromycin, clarithromycin and roxithromycin), along with their synthesis intermediates, byproducts, metabolites and transformation products in wastewater and surface water was developed and validated. Samples were enriched using solid-phase extraction on Oasis HLB cartridges and analyzed by reversed-phase liquid chromatography coupled to electrospray ionization tandem mass spectrometry. The target macrolide compounds were separated on an ACE C18 PFP column and detected using multiple reaction monitoring in positive ionization polarity. The optimized method, which included an additional extract clean-up on strong anion-exchange cartridges (SAX), resulted in high recoveries and accuracies, low matrix effects and improved chromatographic separation of the target compounds, even in highly complex matrices, such as raw wastewater. The developed method was applied to the analysis of macrolide compounds in wastewater and river water samples from Croatia. In addition to parent antibiotics, several previously unreported macrolide transformation products and/or synthesis intermediates were detected in municipal wastewater, some of them reaching μg/L levels. Moreover, extremely high concentrations of macrolides up to mg/L level were found in pharmaceutical industry effluents, indicating possible importance of this source to the total loads into ambient waters. The results revealed a significant contribution of synthesis intermediates and transformation products to the overall mass balance of macrolides in the aquatic environment. Copyright © 2017. Published by Elsevier B.V.

NO EVIDENCE FOR INTERMEDIATE-MASS BLACK HOLES IN GLOBULAR CLUSTERS: STRONG CONSTRAINTS FROM THE JVLA

International Nuclear Information System (INIS)

Strader, Jay; Chomiuk, Laura; Maccarone, Thomas J.; Miller-Jones, James C. A.; Seth, Anil C.; Heinke, Craig O.; Sivakoff, Gregory R.

2012-01-01

With a goal of searching for accreting intermediate-mass black holes (IMBHs), we report the results of ultra-deep Jansky Very Large Array radio continuum observations of the cores of three Galactic globular clusters: M15, M19, and M22. We reach rms noise levels of 1.5-2.1 μJy beam –1 at an average frequency of 6 GHz. No sources are observed at the center of any of the clusters. For a conservative set of assumptions about the properties of the accretion, we set 3σ upper limits on IMBHs from 360 to 980 M ☉ . These limits are among the most stringent obtained for any globular cluster. They add to a growing body of work that suggests either (1) IMBHs ∼> 1000 M ☉ are rare in globular clusters or (2) when present, IMBHs accrete in an extraordinarily inefficient manner.

No Evidence for Intermediate-mass Black Holes in Globular Clusters: Strong Constraints from the JVLA

Science.gov (United States)

Strader, Jay; Chomiuk, Laura; Maccarone, Thomas J.; Miller-Jones, James C. A.; Seth, Anil C.; Heinke, Craig O.; Sivakoff, Gregory R.

2012-05-01

With a goal of searching for accreting intermediate-mass black holes (IMBHs), we report the results of ultra-deep Jansky Very Large Array radio continuum observations of the cores of three Galactic globular clusters: M15, M19, and M22. We reach rms noise levels of 1.5-2.1 μJy beam-1 at an average frequency of 6 GHz. No sources are observed at the center of any of the clusters. For a conservative set of assumptions about the properties of the accretion, we set 3σ upper limits on IMBHs from 360 to 980 M ⊙. These limits are among the most stringent obtained for any globular cluster. They add to a growing body of work that suggests either (1) IMBHs >~ 1000 M ⊙ are rare in globular clusters or (2) when present, IMBHs accrete in an extraordinarily inefficient manner.

Wozu und wie kooperative Arbeitsformen im studienbegleitenden Deutschunterricht?

Directory of Open Access Journals (Sweden)

Karmelka Barić

2016-04-01

Full Text Available Ausgehend von einer Reflexion über die im Beruf und im Leben notwendigen Kompetenzen in der Kommunikation sowie von der Überzeugung, dass es notwendig ist, diese Kompetenzen schon im Studium durch geeignete Arbeitsverfahren und Themen zu entwickeln, werden Kooperation und Autonomie fördernde Arbeitsformen für den studienbegleitenden Deutsch- und Fremdsprachenunterricht (SDU/SFU vorgestellt. Diese Arbeitsformen sind auf andere Sprachen übertragbar und aus dem Lehrwerk Mit Deutsch studieren arbeiten leben A2/B1 (Lévy-Hillerich, Serena, Barić & Cickovska 2010 und der dazu gehörenden Lernplattform entnommen. Das Lehrwerk selbst ist eine Umsetzung der SDU-Rahmencurricula, die im Laufe von über zwanzig Jahren in zehn Ländern im Rahmen eines 1994 am Goethe-Institut Warschau begonnenen Hochschulprojekts und der daraus entstandenen Forschungstätigkeit entstanden sind. Grundlage des Projekts ist ein ganzheitlicher soziopädagogischer Ansatz, der LernerInnen als Menschen betrachtet, die im Präsenz- oder im virtuellen Unterricht in der Sprache und durch die Sprache fach- und sprachübergreifende Kooperationsfähigkeiten entwickeln, die sich später im Leben in der Gesellschaft auswirken. Nach der Vorstellung des Projekts und seiner wissenschaftlichen Hintergründe im ersten Teil des Beitrags werden im zweiten Teil die sich aus dem Ansatz ergebenden Arbeitsformen untersucht: Dabei werden die sich dazu eignenden Themen, die Lernhilfen für StudentInnen, die den LehrerInnen zufallenden Rollen sowie die Ansprüche an Lehrbücher/Unterrichtsmaterialien und Online-/Blended-Learning-Lernszenarien besprochen. Der abschließende Überblick im dritten Teil über die Schwierigkeiten, die beim kooperativen Lernen im SDU/SFU auftreten können, ist gleichzeitig eine offenbleibende Frage danach, wie LehrerInnen aus- und fortgebildet werden sollten, um sich den Anforderungen einer sich dauernd verändernden Lernlandschaft stellen zu können.   The paper

Die Rule of Law im Völker- und im Europarecht – aktuelle Probleme

Directory of Open Access Journals (Sweden)

Helmut Tichy

2015-04-01

Full Text Available Diese am 5. März 2015 in Graz gehaltene Antrittsvorlesung eines Praxisprofessors, der im Hauptberuf Leiter des Völkerrechtsbüros im österreichischen Außenministerium ist, beschäftigt sich mit dem Begriff der Herrschaft des Rechts in den internationalen Beziehungen (Rule of Law und mit den Möglichkeiten Österreichs, zur Stärkung der Rule of Law und zur Lösung aktueller Probleme beizutragen. Dabei werden insbesondere die Mitwirkung an Kodifikationsbemühungen und an der Verbesserung der Einhaltung des humanitären Völkerrechts, die Umsetzung der Menschenrechte (auch in Österreich und Fragen der internationalen Gerichtsbarkeit angesprochen.

Visuell-verbale Beziehungszusammenhänge im Comic. Eine Untersuchung anhand ausgewählter franko-belgischer Comics und der jeweiligen deutschen Übersetzungen.

OpenAIRE

Schröder, Katja

2013-01-01

Comics erfreuen sich bei allen Altersgruppen großer Beliebtheit und bereits in der Kindheit beginnen viele mit dem Lesen von Micky Maus-Magazinen oder Asterix-Bänden. Sie werden im Schulunterricht verwendet, es werden Tagungen, Messen und Festivals (Wichtige Veranstaltungen sind in dieser Hinsicht der Comic-Salon in Erlangen, das Comicfestival München, das Sym-posium zur Förderung und Vernetzung der Comicforschung Comics - Intermedial und Interdisziplinär und vor allem das Festival) zum Them...

Gruppenbezogene Menschenfeindlichkeit im Sport in Sachsen

OpenAIRE

Delto, Hannes; Tzschoppe, Petra

2015-01-01

Mit der Querschnittsstudie „Wir und die Anderen – Gruppenbezogene Menschenfeindlichkeit im organisierten Sport in Sachsen“ wurde erstmals das Syndrom Gruppenbezogener Menschenfeindlichkeit im organisierten Sport untersucht. Das Konzept der Gruppenbezogenen Menschenfeindlichkeit – ausgehend von einer Ideologie der Ungleichwertigkeit – wurde von Prof. Wilhelm Heitmeyer (Universität Bielefeld) entwickelt. Die Ergebnisse ermöglichen explizite Aussagen über Ausmaß und Ursachen Gruppenbezogener Men...

Aerosol Vacuum-Assisted Plasma Ionization (Aero-VaPI) Coupled to Ion Mobility-Mass Spectrometry

Science.gov (United States)

Blair, Sandra L.; Ng, Nga L.; Zambrzycki, Stephen C.; Li, Anyin; Fernández, Facundo M.

2018-02-01

In this communication, we report on the real-time analysis of organic aerosol particles by Vacuum-assisted Plasma Ionization-Mass Spectrometry (Aero-VaPI-MS) using a home-built VaPI ion source coupled to a Synapt G2-S HDMS ion mobility-mass spectrometry (IM-MS) system. Standards of organic molecules of interest in prebiotic chemistry were used to generate aerosols. Monocaprin and decanoic acid aerosol particles were successfully detected in both the positive and negative ion modes, respectively. A complex aerosol mixture of different sizes of polymers of L-malic acid was also examined through ion mobility (IM) separations, resulting in the detection of polymers of up to eight monomeric units. This noncommercial plasma ion source is proposed as a low cost alternative to other plasma ionization platforms used for aerosol analysis, and a higher-performance alternative to more traditional aerosol mass spectrometers. VaPI provides robust online ionization of organics in aerosols without extensive ion activation, with the coupling to IM-MS providing higher peak capacity and excellent mass accuracy. [Figure not available: see fulltext.

X-RAY PROPERTIES OF INTERMEDIATE-MASS BLACK HOLES IN ACTIVE GALAXIES. II. X-RAY-BRIGHT ACCRETION AND POSSIBLE EVIDENCE FOR SLIM DISKS

International Nuclear Information System (INIS)

Desroches, Louis-Benoit; Greene, Jenny E.; Ho, Luis C.

2009-01-01

We present X-ray properties of optically selected intermediate-mass (∼10 5 -10 6 M sun ) black holes (BHs) in active galactic nuclei (AGNs), using data from the Chandra X-Ray Observatory. Our observations are a continuation of a pilot study by Greene and Ho. Of the eight objects observed, five are detected with X-ray luminosities in the range L 0.5-2keV = 10 41 -10 43 erg s -1 , consistent with the previously observed sample. Objects with enough counts to extract a spectrum are well fit by an absorbed power law. We continue to find a range of soft photon indices 1 s -Γ s , consistent with previous AGN studies, but generally flatter than other narrow-line Seyfert 1 active nuclei (NLS1s). The soft photon index correlates strongly with X-ray luminosity and Eddington ratio, but does not depend on BH mass. There is no justification for the inclusion of any additional components, such as a soft excess, although this may be a function of the relative inefficiency of detecting counts above 2 keV in these relatively shallow observations. As a whole, the X-ray-to-optical spectral slope α ox is flatter than in more massive systems, even other NLS1s. Only X-ray-selected NLS1s with very high Eddington ratios share a similar α ox . This is suggestive of a physical change in the accretion structure at low masses and at very high accretion rates, possibly due to the onset of slim disks. Although the detailed physical explanation for the X-ray loudness of these intermediate-mass BHs is not certain, it is very striking that targets selected on the basis of optical properties should be so distinctly offset in their broader spectral energy distributions.

Imaging and mapping of mouse bone using MALDI-imaging mass spectrometry

Directory of Open Access Journals (Sweden)

Yoko Fujino

2016-12-01

Full Text Available Matrix-assisted laser desorption/ionization-imaging mass spectrometry (MALDI-IMS is an advanced method used globally to analyze the distribution of biomolecules on tissue cryosections without any probes. In bones, however, hydroxyapatite crystals make it difficult to determine the distribution of biomolecules using MALDI-IMS. Additionally, there is limited information regarding the use of this method to analyze bone tissues. To determine whether MALDI-IMS analysis of bone tissues can facilitate comprehensive mapping of biomolecules in mouse bone, we first dissected femurs and tibiae from 8-week-old male mice and characterized the quality of multiple fixation and decalcification methods for preparation of the samples. Cryosections were mounted on indium tin oxide-coated glass slides, dried, and then a matrix solution was sprayed on the tissue surface. Images were acquired using an iMScope at a mass-to-charge range of 100–1000. Hematoxylin-eosin, Alcian blue, Azan, and periodic acid-Schiff staining of adjacent sections was used to evaluate histological and histochemical features. Among the various fixation and decalcification conditions, sections from trichloroacetic acid-treated samples were most suitable to examine both histology and comprehensive MS images. However, histotypic MS signals were detected in all sections. In addition to the MS images, phosphocholine was identified as a candidate metabolite. These results indicate successful detection of biomolecules in bone using MALDI-IMS. Although analytical procedures and compositional adjustment regarding the performance of the device still require further development, IMS appears to be a powerful tool to determine the distribution of biomolecules in bone tissues. Keywords: Matrix-assisted laser desorption/ionization-imaging mass spectrometry, Tissue cryosection, Bone, Fixation, Decalcification

Usability test of the ImPRO, computer-based procedure system

International Nuclear Information System (INIS)

Jung, Y.; Lee, J.

2006-01-01

ImPRO is a computer based procedure in both flowchart and success logic tree. It is evaluated on the basis of computer based procedure guidelines. It satisfies most requirements such as presentations and functionalities. Besides, SGTR has been performed with ImPRO to evaluate reading comprehension and situation awareness. ImPRO is a software engine which can interpret procedure script language, so that ImPRO is reliable by nature and verified with formal method. One bug, however, had hidden one year after release, but it was fixed. Finally backup paper procedures can be prepared on the same format as VDU in case of ImPRO failure. (authors)

Midlatitude magnetometer chains during the IMS

International Nuclear Information System (INIS)

Mcpherron, R.L.

1982-01-01

The International Magnetospheric Study (IMS) is an international program to study global problems of magnetospheric dynamics. A key element of the U.S. participation in this program was the establishment of a ground magnetometer network. This network included a number of arrays at high and low latitudes. This report describes three chains established at midlatitudes, including the IMS Midlatitude Chain, the AFGL Magnetometer Network, and the Bell Lab Conjugate Array. Descriptions of the type of equipment, station locations, types of data display, and availability of data for each chain are presented in this report. A major problem of the data analysis phase of the IMS will be reducing selected subsets of these data to a common format. Currently, there are no plans to do this in a systematic manner

The Metallicity Evolution of Blue Compact Dwarf Galaxies from the Intermediate Redshift to the Local Universe

Science.gov (United States)

Lian, Jianhui; Hu, Ning; Fang, Guanwen; Ye, Chengyun; Kong, Xu

2016-03-01

We present oxygen abundance measurements for 74 blue compact dwarf (BCD) galaxies in the redshift range of [0.2, 0.5] using the strong-line method. The spectra of these objects are taken using Hectospec on the Multiple Mirror Telescope. More than half of these BCDs had dust attenuation corrected using the Balmer decrement method. For comparison, we also selected a sample of 2023 local BCDs from the Sloan Digital Sky Survey (SDSS) database. Based on the local and intermediate-z BCD samples, we investigated the cosmic evolution of the metallicity, star formation rate (SFR), and Dn(4000) index. Compared with local BCDs, the intermediate-z BCDs had a systematically higher R23 ratio but a similar O32 ratio. Interestingly, no significant deviation in the mass-metallicity (MZ) relation was found between the intermediate-z and local BCDs. Besides the metallicity, the intermediate-z BCDs also exhibited an SFR distribution that was consistent with local BCDs, suggesting a weak dependence on redshift. The intermediate-z BCDs seemed to be younger than the local BCDs with lower Dn(4000) index values. The insignificant deviation in the mass-metallicity and mass-SFR relations between intermediate-z and local BCDs indicates that the relations between the global parameters of low-mass compact galaxies may be universal. These results from low-mass compact galaxies could be used to place important observational constraints on galaxy formation and evolution models.

Emsission of intermediate mass fragments in the p(1.9 GeV)+natNI reaction

International Nuclear Information System (INIS)

Bubak, A.

2004-06-01

The emission of the intermediate mass fragments (IMFs; 2 ≤ Z ≤ 14) produced in the interaction of 1.9 GeV protons with nickel ( nat Ni) has been a subject of interest of the present study. Energy spectra of isotopically and elementally identified ejectiles have been measured at angles 15 and 120 with the respect to the beam direction. The identification of the emitted IMFs has been performed by means of the Bragg curve spectroscopy and the time-of-flight technique (TOF). The Bragg curve detectors (BCDs) were employed for the charge identification, whereas the TOF method combined with the BCD, for the mass identification. The main task of the present PhD thesis was to built appropriate data acquisition system, to perform the experiment on the internal beam of the COSY accelerator, to propose the methodology of the off-line analysis of the data, to apply it to the event-by-event stored data, and to perform the phenomenological analysis of the obtained data. The results, experimental procedures, and different techniques of the element and isotope identification by means of the BCD + TOF are presented. The determination of the power law parameter τ characterizing the mass and charge distributions of the reaction products is discussed. Various methods of the nuclear matter temperature determination, the comparison between nuclear matter thermometers, and the discussion of the obtained results, shown in the energy-temperature diagram (the so called caloric curve), are presented as well. The results suggest two different mechanisms of the IMFs production: from the equilibrated (IMFs measured at 120 ), and non-equilibrated (IMFs measured at 15 ) state of the nucleus. (orig.)

Implantate im Mittelohrbereich - Teil 2 (Ergänzungen 2007)

Science.gov (United States)

Stieve, M.; Lenarz, Thomas

In Deutschland leben ca. 12 Millionen Menschen, die an einer ein- oder beidseitigen Schwerhörigkeit leiden. Diese kann angeboren oder im Laufe des Lebens erworben sein. Klinisch und therapeutisch wichtig ist die Unterscheidung hinsichtlich des Schädigungsortes im Bereich des Mittelohres, d. h. eine Schalleitungsschwerhörigkeit, oder im Bereich des Innenohres, d. h. eine Schallempfindungsschwerhörigkeit, wobei hier der Schädigungsort auch am Hörnerven oder in den zentralen Hörabschnitten liegen kann. Therapeutisch lassen sich sowohl Schwerhörigkeiten im Bereich des Mittelohres als auch im Innenohr und sogar im Hirnstammbereich (Hirnstammimplantat) behandeln. 1,9 Millionen Schwerhörige haben eine Erkrankung im Mittelohrbereich, d. h. der Schall kann nur ungenügend auf das Innenohr übertragen werden. Die Ursache besteht meist in einer chronischen Mittelohrentzündung, die zu einer Zerstörung des Trommelfells und der Gehörknöchelchenkette geführt haben. Therapeutisch und damit als Prinzip der operativen Hörverbesserung steht primär der Verschluß des Trommelfells oder eine Rekonstruktion der Gehörknöchelchen. Mittelohroperationen werden mikrochirurgisch unter dem Operationsmikroskop durchgeführt, wobei zunächst durch eine sanierende Operation der Entzündungsprozeß entfernt wird und nach einer Ausheilungszeit die Gehörknöchelchenkette durch künstliche Prothesen rekonstruiert werden kann.

Minería de imágenes

OpenAIRE

Fernández, Jacqueline; Miranda, Natalia Carolina; Guerrero, Roberto A.; Piccoli, María Fabiana

2006-01-01

Durante los últimos años, la proliferación de los medios digitales ha creado la necesidad del desarrollo de herramientas para la eficiente representación, acceso y recuperación de información visual. La minería de imágenes se ha convertido en una importante rama de investigación a causa del potencial que posee en descubrir patrones característicos a partir de un importante conjunto de imágenes. No obstante, la minería de imágenes es más que una simple extensión de la minería de datos al domin...

Isochronicity corrections for isochronous mass measurements at the HIRFL-CSRe

International Nuclear Information System (INIS)

Gao, Xiang; Yuan, You-Jin; Yang, Jian-cheng; Litvinov, S.; Wang, Meng; Litvinov, Y.; Zhang, Wei; Yin, Da-Yu; Shen, Guo-Dong; Chai, Wei-ping; Shi, Jian; Shang, Peng

2014-01-01

Isochronous Mass Spectrometry (IMS) is a unique experimental method for mass measurement experiments on short-lived nuclei. Mass measurements of 78 Kr projectile fragments were performed in HIRFL-CSRe at the Institute of Modern Physics (IMP), Chinese Academy of Sciences. The short-lived secondary beams were produced by bombarding a 15 mm thick beryllium-target in the Radioactive Ion Beam Line (RIBLL2) and were then injected into the CSRe storage ring. The masses of stored ions were measured by employing the IMS technique, which is based on the determination of the ion revolution times. A dedicated time-of-flight (TOF) detector is used for the latter purpose. However, the isochronicity, and thus the mass resolving power, depends on the momentum spread and the transverse emittance of the injected beams, Here, we present the first-order isochronicity optimization, the chromaticity and second-order isochronicity corrections through the modification of the quadrupole and sextupole field strengths. With the help of these corrections, the mass resolution of Δm/m=10 −6 can be achieved

Isochronicity corrections for isochronous mass measurements at the HIRFL-CSRe

Energy Technology Data Exchange (ETDEWEB)

Gao, Xiang [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Graduate University of Chinese Academy of Sciences, Beijing 100049 (China); Yuan, You-Jin; Yang, Jian-cheng [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Litvinov, S. [GSI, Helmholtzzentrum für Schwerionenforschung GmbH, 64291 Darmstadt (Germany); Wang, Meng [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Litvinov, Y. [GSI, Helmholtzzentrum für Schwerionenforschung GmbH, 64291 Darmstadt (Germany); Zhang, Wei; Yin, Da-Yu [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Shen, Guo-Dong [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Graduate University of Chinese Academy of Sciences, Beijing 100049 (China); Chai, Wei-ping; Shi, Jian [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Shang, Peng [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Graduate University of Chinese Academy of Sciences, Beijing 100049 (China)

2014-11-01

Isochronous Mass Spectrometry (IMS) is a unique experimental method for mass measurement experiments on short-lived nuclei. Mass measurements of {sup 78}Kr projectile fragments were performed in HIRFL-CSRe at the Institute of Modern Physics (IMP), Chinese Academy of Sciences. The short-lived secondary beams were produced by bombarding a 15 mm thick beryllium-target in the Radioactive Ion Beam Line (RIBLL2) and were then injected into the CSRe storage ring. The masses of stored ions were measured by employing the IMS technique, which is based on the determination of the ion revolution times. A dedicated time-of-flight (TOF) detector is used for the latter purpose. However, the isochronicity, and thus the mass resolving power, depends on the momentum spread and the transverse emittance of the injected beams, Here, we present the first-order isochronicity optimization, the chromaticity and second-order isochronicity corrections through the modification of the quadrupole and sextupole field strengths. With the help of these corrections, the mass resolution of Δm/m=10{sup −6} can be achieved.

Die Pluralbildung im Deutschen - ein Versuch im Rahmen der Optimalitätstheorie

Directory of Open Access Journals (Sweden)

Wegener, Heide

1999-01-01

Full Text Available Die Pluralbildung im Deutschen ist nicht chaotisch, aber komplex. Unabhängig davon, ob man für die Pluralbildung Regeln, Schemata oder die Wortstruktur als Erklärungsmodell benutzt, bleibt die Tatsache einer beachtlichen Zahl miteinander konkurrierender Formen zu erklären. Dies gilt schon deshalb, weil die Variation unter den Pluralformen wohl mit dazu beiträgt, dass trotz der Arbeiten von Mugdan 1977 und Köpcke 1987, 1993, der klaren Darstellung des Pluralsystems in vielen Grammatiken, z.B. Eisenberg 1986, 1989, 1998 noch immer bisweilen die Meinung besteht, die Pluralbildung im Deutschen sei arbiträr.Es soll gezeigt werden, dass das Pluralsystem des Deutschen nach Beschränkungen aufgebaut ist, die morphologischer und silbenphonologischer Natur sind und sich im Rahmen der Optimalitätstheorie (OT beschreiben lassen. Die OT nimmt an, dass Wortformen universalen Beschränkungen (Constraints unterliegen, und dass diese prinzipiell verletzbar sind. Ich werde zunächst die für die Pluralbildung relevanten Beschränkungen definieren, dann an heimischen Pluralformen und -varianten ihr Zusammenwirken zeigen und schließlich den Assimilationsprozess von Fremdwörtern mit Hilfe dieser Beschränkungen und der Beschränkungshierarchien zu erklären versuchen. Daran werden schließlich Überlegungen zu Verarbeitung und Lernbarkeit der Pluralformen geknüpft.

Medienerziehung im Vorschulbereich - Zum Projekt Mediengarten der Wiener Medienpädagogik

Directory of Open Access Journals (Sweden)

Gudrun Kern

2010-09-01

Full Text Available Im Zuge des Projekts Mediengarten der Wiener Medienpädagogik wurde in Kooperation mit angehenden KindergartenpädagogInnen eine Medienerziehung im Sinne einer Auseinandersetzung über Medien im Vorschulbereich anhand konkreter Angebote in Kindergärten konzipiert. Im folgenden Artikel werden die Schwerpunktsetzungen dieses Konzepts vorgestellt und durch praktische Beispiele verdeutlicht.

Cyberbullying und Empathie : affektive, kognitive und medienbasierte Empathie im Kontext von Cyberbullying im Kindes- und Jugendalter

OpenAIRE

Pfetsch, Jan; Müller, Christin R.; Ittel, Angela

2014-01-01

"Bei medial vermittelter Kommunikation sinkt sowohl die Hemmschwelle für aggressive Verhaltensweisen wie Cyberbullying als auch die Wahrscheinlichkeit empathischer Reaktionen. Im Fokus der vorliegenden Studie mit 979 Schülerinnen und Schülern der 4.-8. Klassen (M=12.01, SD=1.68 Jahre, 55% weiblich) stand die Frage, ob Cyberbullies geringere Ausprägungen für affektive, kognitive und medienbasierte Empathie aufweisen als Unbeteiligte. Empathie wurde im Selbst- und Peerbericht erhoben. Hypothese...

Discrimination of bacteria by rapid sensing their metabolic volatiles using an aspiration-type ion mobility spectrometer (a-IMS) and gas chromatography-mass spectrometry GC-MS.

Science.gov (United States)

Ratiu, Ileana Andreea; Bocos-Bintintan, Victor; Patrut, Adrian; Moll, Victor Hugo; Turner, Matthew; Thomas, C L Paul

2017-08-22

The objective of our study was to investigate whether one may quickly and reliably discriminate different microorganism strains by direct monitoring of the headspace atmosphere above their cultures. Headspace samples above a series of in vitro bacterial cultures were directly interrogated using an aspiration type ion mobility spectrometer (a-IMS), which produced distinct profiles ("fingerprints") of ion currents generated simultaneously by the detectors present inside the ion mobility cell. Data processing and analysis using principal component analysis showed net differences in the responses produced by volatiles emitted by various bacterial strains. Fingerprint assignments were conferred on the basis of product ion mobilities; ions of differing size and mass were deflected in a different degree upon their introduction of a transverse electric field, impacting finally on a series of capacitors (denominated as detectors, or channels) placed in a manner analogous to sensor arrays. Three microorganism strains were investigated - Escherichia coli, Bacillus subtilis and Staphylococcus aureus; all strains possess a relatively low pathogenic character. Samples of air with a 5 cm 3 volume from the headspace above the bacterial cultures in agar growth medium were collected using a gas-tight chromatographic syringe and injected inside the closed-loop pneumatic circuit of the breadboard a-IMS instrument model ChemPro-100i (Environics Oy, Finland), at a distance of about 1 cm from the ionization source. The resulting chemical fingerprints were produced within two seconds from the moment of injection. The sampling protocol involved to taking three replicate samples from each of 10 different cultures for a specific strain, during a total period of 72 h after the initial incubation - at 24, 48 and 72 h, respectively. Principal component analysis (PCA) was used to discriminate between the IMS fingerprints. PCA was found to successfully discriminate between bacteria at three

Instrumentale Spielformeln und Vokale Verzierungen im 16.Jahrhundert

Directory of Open Access Journals (Sweden)

Göllner, Theodor

2001-12-01

Full Text Available In the music of the 16th century, stereotype four-note formulas are found in the instrumental as well as in the vocal idiom. Although frequently identical in appearance, their functions are very different. While indispensable in the instrumental idiom, particularly in keyboard music, where they represent the very essence of instruction in 15th-century organ treatises and fundamenta, they appear in vocal music only as additions to finished compositions or existing practices. What amounts to an absolute necessity in one case is merely an ornamental supplement in the other. In vocal music it is treated as a matter of performance carried out by a qualified soloist and limited to the musical centers of Italy. The present article raises the question as to how the genuinely instrumental and widely spread keyboard practice made its impact on the vocal ornaments of the singer, whose primary concern is the musical communication of language.

[de] Die in der Musik des 16. Jahrhunderts im Instrumentalen wie im Vokalen vorkommenden, meist viertönigen, stereotypen Formeln sind zwar in beiden Bereichen weitgehend identisch, doch von höchst unterschiedlicher Funktion. Während sie im Instrumentalen, besonders in der Tastenmusik, unverzichtbar sind und schon im 15. Jahrhundert den Kern der Orgeltraktate und Fundamenta bilden, treten sie im Vokalen zu einer fertigen Komposition oder bestehenden Praxis hinzu. Was im einen Fall eine unbedingte Notwendigkeit ist, wird im anderen zu einem nachträglichen Ornament, das sich oft erst bei der Aufftührung einstellt, den qualifizierten Solosänger voraussetzt und auf die musikalischen Zentren Italiens konzentriert war. Der Artikel versucht zu klären, wie sich das genuin instrumentale, allgemein verbreitete Tastenspiel auf die spezielle Verzierungskunst des Sängers auswirkt, dessen primäre Aufgabe es ist, Sprache musikalisch zu vermitteln.

Automatic registration of imaging mass spectrometry data to the Allen Brain Atlas transcriptome

Science.gov (United States)

Abdelmoula, Walid M.; Carreira, Ricardo J.; Shyti, Reinald; Balluff, Benjamin; Tolner, Else; van den Maagdenberg, Arn M. J. M.; Lelieveldt, B. P. F.; McDonnell, Liam; Dijkstra, Jouke

2014-03-01

Imaging Mass Spectrometry (IMS) is an emerging molecular imaging technology that provides spatially resolved information on biomolecular structures; each image pixel effectively represents a molecular mass spectrum. By combining the histological images and IMS-images, neuroanatomical structures can be distinguished based on their biomolecular features as opposed to morphological features. The combination of IMS data with spatially resolved gene expression maps of the mouse brain, as provided by the Allen Mouse Brain atlas, would enable comparative studies of spatial metabolic and gene expression patterns in life-sciences research and biomarker discovery. As such, it would be highly desirable to spatially register IMS slices to the Allen Brain Atlas (ABA). In this paper, we propose a multi-step automatic registration pipeline to register ABA histology to IMS- images. Key novelty of the method is the selection of the best reference section from the ABA, based on pre-processed histology sections. First, we extracted a hippocampus-specific geometrical feature from the given experimental histological section to initially localize it among the ABA sections. Then, feature-based linear registration is applied to the initially localized section and its two neighbors in the ABA to select the most similar reference section. A non-rigid registration yields a one-to-one mapping of the experimental IMS slice to the ABA. The pipeline was applied on 6 coronal sections from two mouse brains, showing high anatomical correspondence, demonstrating the feasibility of complementing biomolecule distributions from individual mice with the genome-wide ABA transcriptome.

Search for ternary fragmentation in the reaction 856 MeV 98Mo + 51V: Kinematic probing of intermediate-mass-fragment emissions

International Nuclear Information System (INIS)

Vardaci, Emanuele; Kaplan, Morton; Parker, Winifred E.; Moses, David J.; Boger, J.T.; Gilfoyle, G.T.; McMahan, M.A.; Montoya, M.

2000-05-01

A new technique has been applied to coincidence measurements between fission fragments (FF) and intermediate mass fragments (IMF) emitted from the composite system 149 65 Tb at an excitation energy of 224 MeV. The method permits simultaneous observation of IMF emissions along and normal to the FF separation axes. For the integrated total of 0.10 +-0.02 IMF emitted per fission, we find no significant correlation with FF direction, suggesting that IMFs associated with fission reactions are predominantly emitted from the system prior to fission

Next-generation technologies for spatial proteomics: Integrating ultra-high speed MALDI-TOF and high mass resolution MALDI FTICR imaging mass spectrometry for protein analysis.

Science.gov (United States)

Spraggins, Jeffrey M; Rizzo, David G; Moore, Jessica L; Noto, Michael J; Skaar, Eric P; Caprioli, Richard M

2016-06-01

MALDI imaging mass spectrometry is a powerful analytical tool enabling the visualization of biomolecules in tissue. However, there are unique challenges associated with protein imaging experiments including the need for higher spatial resolution capabilities, improved image acquisition rates, and better molecular specificity. Here we demonstrate the capabilities of ultra-high speed MALDI-TOF and high mass resolution MALDI FTICR IMS platforms as they relate to these challenges. High spatial resolution MALDI-TOF protein images of rat brain tissue and cystic fibrosis lung tissue were acquired at image acquisition rates >25 pixels/s. Structures as small as 50 μm were spatially resolved and proteins associated with host immune response were observed in cystic fibrosis lung tissue. Ultra-high speed MALDI-TOF enables unique applications including megapixel molecular imaging as demonstrated for lipid analysis of cystic fibrosis lung tissue. Additionally, imaging experiments using MALDI FTICR IMS were shown to produce data with high mass accuracy (z 5000) for proteins up to ∼20 kDa. Analysis of clear cell renal cell carcinoma using MALDI FTICR IMS identified specific proteins localized to healthy tissue regions, within the tumor, and also in areas of increased vascularization around the tumor. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

IMS applications analysis

Energy Technology Data Exchange (ETDEWEB)

RODACY,PHILIP J.; REBER,STEPHEN D.; SIMONSON,ROBERT J.; HANCE,BRADLEY G.

2000-03-01

This report examines the market potential of a miniature, hand-held Ion Mobility Spectrometer. Military and civilian markets are discussed, as well as applications in a variety of diverse fields. The strengths and weaknesses of competing technologies are discussed. An extensive Ion Mobility Spectrometry (IMS) bibliography is included. The conclusions drawn from this study are: (1) There are a number of competing technologies that are capable of detecting explosives, drugs, biological, or chemical agents. The IMS system currently represents the best available compromise regarding sensitivity, specificity, and portability. (2) The military market is not as large as the commercial market, but the military services are more likely to invest R and D funds in the system. (3) Military applications should be addressed before commercial applications are addressed. (4) There is potentially a large commercial market for rugged, hand-held Ion Mobility Spectrometer systems. Commercial users typically do not invest R and D funds in this type of equipment rather, they wait for off-the-shelf availability.

A Management Tool for Improvement (Improving) IMS Stations Performance

International Nuclear Information System (INIS)

Mohammad, D.; Pantin, A.; Quintana, E.

2011-01-01

IMS-Maintenance is a software under development by the personnel of ARN-CTBT office, intended for the technical management of IMS stations under ARN's responsibility. This software integrates the whole control of the equipment in an IMS station, including the management of consumables used in daily or periodic operation. It permits an easy retrieval (access) of the technical features, suppliers, etc. of each item of the equipment, as well as its maintenance history and scheduled task. Although this project is still in a starting phase, a preliminary version of this software is being used in radionuclide station RN01 (Buenos Aires), having already demonstrated its usefulness and potential for the improvement of IMS station management. (authors)

Radiological information management system (RadIMS)

International Nuclear Information System (INIS)

Oesterling, R.G.; Marko, S.A.; Tschaeche, A.N.

1991-01-01

Westinghouse Idaho Nuclear Company, Inc. (WINCO) is developing and implementing an information management system, known as RadIMS, to track and record personnel exposure to ionizing radiation. RadIMS has been designed to fulfill all the requirements of US Department of Energy (USDOE) Order 5480.11, ''Radiation Protection for Occupational Workers.'' This Order requires the contractor to maintain detailed radiation exposure records on all individuals who work at the facility. These records must be retrievable for the entire working life of the individual and be available to other USDOE contractors on request. To meet these general needs, RadIMS provides for retrieval of detailed, comprehensive individual exposure histories as well as the usual online interactions to accomplish day-today radiation protection operations. These two extremes of functionality require different approaches in the WINCO computing environment. The exposure histories include database text, paper, microfilm, and electronic bitmaps

Radiological information management system (RadIMS)

Energy Technology Data Exchange (ETDEWEB)

Oesterling, R.G.; Marko, S.A.; Tschaeche, A.N.

1991-08-19

Westinghouse Idaho Nuclear Company, Inc. (WINCO) is developing and implementing an information management system, known as RadIMS, to track and record personnel exposure to ionizing radiation. RadIMS has been designed to fulfill all the requirements of US Department of Energy (USDOE) Order 5480.11, Radiation Protection for Occupational Workers.'' This Order requires the contractor to maintain detailed radiation exposure records on all individuals who work at the facility. These records must be retrievable for the entire working life of the individual and be available to other USDOE contractors on request. To meet these general needs, RadIMS provides for retrieval of detailed, comprehensive individual exposure histories as well as the usual online interactions to accomplish day-today radiation protection operations. These two extremes of functionality require different approaches in the WINCO computing environment. The exposure histories include database text, paper, microfilm, and electronic bitmaps.

Radiological information management system (RadIMS)

Energy Technology Data Exchange (ETDEWEB)

Oesterling, R.G.; Marko, S.A.; Tschaeche, A.N.

1991-08-19

Westinghouse Idaho Nuclear Company, Inc. (WINCO) is developing and implementing an information management system, known as RadIMS, to track and record personnel exposure to ionizing radiation. RadIMS has been designed to fulfill all the requirements of US Department of Energy (USDOE) Order 5480.11, ``Radiation Protection for Occupational Workers.`` This Order requires the contractor to maintain detailed radiation exposure records on all individuals who work at the facility. These records must be retrievable for the entire working life of the individual and be available to other USDOE contractors on request. To meet these general needs, RadIMS provides for retrieval of detailed, comprehensive individual exposure histories as well as the usual online interactions to accomplish day-today radiation protection operations. These two extremes of functionality require different approaches in the WINCO computing environment. The exposure histories include database text, paper, microfilm, and electronic bitmaps.

The future of the IMS Learning Design specification: a critical look

NARCIS (Netherlands)

Sloep, Peter

2009-01-01

P. B. Sloep (2009). The future of the IMS Learning Design specification: a critical look. Presentation at the IMS Learning Design seminar 'The future of IMS Learning Design'. December, 10, 2009, Wollongong, Australia: University of Wollongong.

Im Wind / Mari Vallisoo ; tõlk. Gisbert Jänicke

Index Scriptorium Estoniae

Vallisoo, Mari, 1950-2013

2003-01-01

Sisu: Im Wind = Tuulega ; Zwei Frauen = Kaks naist ; In Gedanken an Aleksander Levin = aleksander Levinile mõteldes ; Jetzt im Dunkel = Nüüd pimedas ; Fragen = Küsimused ; Der Zwillingsbruder = Kaksikvend

The MHD intermediate shock interaction with an intermediate wave: Are intermediate shocks physical?

International Nuclear Information System (INIS)

Wu, C.C.

1988-01-01

Contrary to the usual belief that MHD intermediate shocks are extraneous, the authors have recently shown by numerical solutions of dissipative MHD equations that intermediate shocks are admissible and can be formed through nonlinear steepening from a continuous wave. In this paper, he clarifies the differences between the conventional view and the results by studying the interaction of an MHD intermediate shock with an intermediate wave. The study reaffirms his results. In addition, the study shows that there exists a larger class of shocklike solutions in the time-dependent dissiaptive MHD equations than are given by the MHD Rankine-Hugoniot relations. it also suggests a mechanism for forming rotational discontinuities through the interaction of an intermediate shock with an intermediate wave. The results are of importance not only to the MHD shock theory but also to studies such as magnetic field reconnection models

Transplantate und Implantate im Mittelohrbereich - Teil 1 (Stand 2002)

Science.gov (United States)

Kempf, Hans-Georg; Lenarz, Thomas; Eckert, Karl-Ludwig

In Deutschland leben ungefähr 12 Millionen Menschen, die an einer ein- oder beidseitigen Schwerhörigkeit leiden. Diese kann angeboren oder im Laufe des Lebens erworben sein. Klinisch und therapeutisch wichtig ist die Unterscheidung, ob die Ursache der Schwerhörigkeit im Bereich des Mittelohres, d. h. der Schallübertragung, oder im Bereich des Innenohres, der Hörnerven und der zentralen Hörbahnabschnitte, d. h. der Schallempfindung, liegt. 2,5 Millionen Schwerhörige haben dabei das Problem der Schallübertragung, d.h. die Störung liegt im Mittelohrbereich, und hier kann man in der Regel mit operativen, mikrochirurgisch durchgeführten Massnahmen helfen [1, 2]. Im Vordergrund steht als Ursache hier die chronische Mittelohrentzündung, die sich als Perforation des Trommelfells, als Defekt oder Unterbrechung der Gehörknöchelchen oder auch als Cholesteatom, einer sogenannte Knocheneiterung äussern kann [3]. Therapeutisch und damit als Prinzip der operativen Hörverbesserung steht primär der Verschluss des Trommelfells oder eine Rekonstruktion der Gehörknöchelchen an.

Coherent ambient infrasound recorded by the global IMS network

Science.gov (United States)

Matoza, R. S.; Landes, M.; Le Pichon, A.; Ceranna, L.; Brown, D.

2011-12-01

The International Monitoring System (IMS) includes a global network of infrasound arrays, which is designed to detect atmospheric nuclear explosions anywhere on the planet. The infrasound network also has potential application in detection of natural hazards such as large volcanic explosions and severe weather. Ambient noise recorded by the network includes incoherent wind noise and coherent infrasound. We present a statistical analysis of coherent infrasound recorded by the IMS network. We have applied broadband (0.01 to 5 Hz) array processing systematically to the multi-year IMS historical dataset (2005-present) using an implementation of the Progressive Multi-Channel Correlation (PMCC) algorithm in log-frequency space. We show that IMS arrays consistently record coherent ambient infrasound across the broad frequency range from 0.01 to 5 Hz when wind-noise levels permit. Multi-year averaging of PMCC detection bulletins emphasizes continuous signals such as oceanic microbaroms, as well as persistent transient signals such as repetitive volcanic, surf, or anthropogenic activity (e.g., mining or industrial activity). While many of these continuous or repetitive signals are of interest in their own right, they may dominate IMS array detection bulletins and obscure or complicate detection of specific signals of interest. The new PMCC detection bulletins have numerous further applications, including in volcano and microbarom studies, and in IMS data quality assessment.

Gruppenbezogene Menschenfeindlichkeit im Sport in Sachsen-Anhalt

OpenAIRE

Delto, Hannes; Tzschoppe, Petra

2016-01-01

Mit der Querschnittsstudie „Wir und die Anderen – Gruppenbezogene Menschenfeindlichkeit im organisierten Sport in Sachsen-Anhalt“ wurde das Syndrom Gruppenbezogener Menschenfeindlichkeit im organisierten Sport untersucht. Das Konzept der Gruppenbezogenen Menschenfeindlichkeit – ausgehend von einer Ideologie der Ungleichwertigkeit – wurde von Prof. Wilhelm Heitmeyer (Universität Bielefeld) entwickelt. Die Ergebnisse ermöglichen explizite Aussagen über Ausmaß und Ursachen Gruppenbezogener Mensc...

Freie Lerninhalte im Internet mit Studierenden recherchieren, kommentieren und kompilieren. Zur Gestaltung der online-Selbstlernangebote im hr-Funkkolleg Philosophie

Directory of Open Access Journals (Sweden)

Jakob Krebs

2017-03-01

Full Text Available Wie lassen sich online frei verfügbare Bildungsinhalte mit Studierenden so zusammenstellen, dass sie als thematisch sortierte Selbstlernmaterialien unkompliziert gefunden werden können – sei es von anderen Studierenden, interessierten Laien oder auch von Lehrkräften in Bildungsinstitutionen? Der vorliegende Werkstattbericht rekonstruiert ein Lernszenario, in dem Studierende vorhandene Materialien im Internet recherchierten, kommentierten und kompilierten, um ein Online-Zusatzangebot zu den Radiosendungen im hr-Funkkolleg Philosophie 2014/15 zu erstellen. Die Rahmenbedingungen dieser ungewöhnlichen universitären Kooperation mit dem Rundfunk werden im ersten Abschnitt vorgestellt. Der zweite Abschnitt skizziert das didaktische Design zusammen mit dem Projektstrukturplan eines produktorientierten kollaborativen Lernsettings mit Wiki-Einsatz. Im dritten Abschnitt werden der Lernerfolg bei den Studierenden sowie einige Herausforderungen benannt, die u. a. in der Abschlussevaluierung zur Sprache kamen. Der vierte Abschnitt macht die Projekterfahrungen für reguläre Lehr- und Lern-Szenarien fruchtbar, in denen nicht nur Studierende mit didaktischen Interessen durch die gemeinsame Gestaltung von Internetangeboten fachlich und methodisch profitieren können. Mit dem Bericht wird somit u. a. veranschaulicht, wie sich Ansätze von Blended, Peer-Assisted und Service Learning produktiv kombinieren lassen.

Protoplanetary disks around intermediate-mass stars: the asset of imaging in the mid-infrared

International Nuclear Information System (INIS)

Doucet, Coralie

2006-01-01

The accrued efficiency of the instruments in many wavelengths has allowed to show that most young stellar objects were surrounded by circumstellar matter distributed in a disk. Direct imaging of such systems is very difficult because of their narrow angular size and their weak luminosity in comparison with the star. Nowadays, 50 % of low-mass pre-main sequence stars, i.e. T Tauri stars, are surrounded by a disk. This proportion is less obvious for intermediate-mass stars, like Herbig Ae stars, that are less numerous and whose direct disk detection is more difficult. Until now, only the interpretation of the Spectral Energy Distribution (SED) of such objects allows to have access to the geometry of the disk. But the solutions are degenerated and several parameters fit the same SED. It is essential to have direct images of the objects, the only evidence of the presence of disks. This PhD allows to show that mid-infrared imaging could rise a part of the degeneracy of the disk's parameters linked to the fit of the SED for several objects and gives constraints on the minimum external radius and inclination of the disk. We present a new observation mode with VISIR, the mid-infrared imager and spectrometer on the VLT (ESO, Chile): the so-called BURST mode. This mode allows to reach the diffraction limit of the telescope. Thanks to mid-infrared imaging with this instrument, we were able, for the first time, to have access to the geometry of a disk (flared structure) around a massive star that was, until now, only deduced from the SED modelling. (author) [fr

A tidal disruption event in a nearby galaxy hosting an intermediate mass black hole

Energy Technology Data Exchange (ETDEWEB)

Donato, D.; Troja, E. [CRESST and Astroparticle Physics Laboratory NASA/GSFC, Greenbelt, MD 20771 (United States); Cenko, S. B.; Fox, O. [Astrophysics Science Division, NASA/GSFC, Mail Code 661, Greenbelt, MD 20771 (United States); Covino, S. [INAF, Osservatorio Astronomico di Brera, via E. Bianchi 46, I-23807 Merate (Italy); Pursimo, T. [Nordic Optical Telescope, Apartado 474, E-38700 Santa Cruz de La Palma (Spain); Cheung, C. C. [Space Science Division, Naval Research Laboratory, Washington, DC 20375-5352 (United States); Kutyrev, A. [Observational Cosmology Laboratory, NASA/GSFC, 8800 Greenbelt Road, Greenbelt, MD 20771-2400 (United States); Campana, S.; Fugazza, D. [Joint Space Science Institute, University of Maryland, College Park, MD 20742 (United States); Landt, H. [Department of Physics, Durham University, South Road, Durham DH1 3LE (United Kingdom); Butler, N. R., E-mail: davide.donato-1@nasa.gov [School of Earth and Space Exploration, Arizona State University, Tempe, AZ 85287 (United States)

2014-02-01

We report the serendipitous discovery of a bright point source flare in the Abell cluster A1795 with archival EUVE and Chandra observations. Assuming the EUVE emission is associated with the Chandra source, the X-ray 0.5-7 keV flux declined by a factor of ∼2300 over a time span of 6 yr, following a power-law decay with index ∼2.44 ± 0.40. The Chandra data alone vary by a factor of ∼20. The spectrum is well fit by a blackbody with a constant temperature of kT ∼ 0.09 keV (∼10{sup 6} K). The flare is spatially coincident with the nuclear region of a faint, inactive galaxy with a photometric redshift consistent at the 1σ level with the cluster (z = 0.062476). We argue that these properties are indicative of a tidal disruption of a star by a black hole (BH) with log (M {sub BH}/M {sub ☉}) ∼ 5.5 ± 0.5. If so, such a discovery indicates that tidal disruption flares may be used to probe BHs in the intermediate mass range, which are very difficult to study by other means.

A tidal disruption event in a nearby galaxy hosting an intermediate mass black hole

International Nuclear Information System (INIS)

Donato, D.; Troja, E.; Cenko, S. B.; Fox, O.; Covino, S.; Pursimo, T.; Cheung, C. C.; Kutyrev, A.; Campana, S.; Fugazza, D.; Landt, H.; Butler, N. R.

2014-01-01

We report the serendipitous discovery of a bright point source flare in the Abell cluster A1795 with archival EUVE and Chandra observations. Assuming the EUVE emission is associated with the Chandra source, the X-ray 0.5-7 keV flux declined by a factor of ∼2300 over a time span of 6 yr, following a power-law decay with index ∼2.44 ± 0.40. The Chandra data alone vary by a factor of ∼20. The spectrum is well fit by a blackbody with a constant temperature of kT ∼ 0.09 keV (∼10 6 K). The flare is spatially coincident with the nuclear region of a faint, inactive galaxy with a photometric redshift consistent at the 1σ level with the cluster (z = 0.062476). We argue that these properties are indicative of a tidal disruption of a star by a black hole (BH) with log (M BH /M ☉ ) ∼ 5.5 ± 0.5. If so, such a discovery indicates that tidal disruption flares may be used to probe BHs in the intermediate mass range, which are very difficult to study by other means.

[Application of Imaging Mass Spectrometry for Drug Discovery].

Science.gov (United States)

Hayasaka, Takahiro

2016-01-01

Imaging mass spectrometry (IMS) can reveal the distribution of biomolecules on tissue sections. In this process, the biomolecules are directly ionized within tissue sections using matrix-assisted laser desorption/ionization, and then their distribution is visualized by pseudo-color based on the relative signal intensity. The biomolecules, such as fatty acids, phospholipids, glycolipids, peptides, proteins, and neurotransmitters, have been analyzed at a spatial resolution of 5 μm. A special instrument for IMS analysis was developed by Shimadzu. The IMS analysis does not require the labeling of biomolecules and is capable of analyzing all the ionized biomolecules. Interest in this method has expanded to many research fields, including biology, agriculture, medicine, and pharmacology. The technique is especially relevant to the drug discovery process. As practiced currently, drug discovery is expensive and time consuming, requiring the preparation of probes for each drug and its metabolites, followed by systematic probe tracking in animal models. The IMS technique is expected to overcome these drawbacks by revealing the distribution of drugs and their metabolites using only a single analysis. In this symposium, I introduced the methodology and applications of IMS and discussed the feasibility of its application to drug discovery in the near future.

Laser desorption/ionization mass spectrometry for direct profiling and imaging of small molecules from raw biological materials

Energy Technology Data Exchange (ETDEWEB)

Cha, Sangwon [Iowa State Univ., Ames, IA (United States)

2008-01-01

Matrix-assisted laser desorption/ionization(MALDI) mass spectrometry(MS) has been widely used for analysis of biological molecules, especially macromolecules such as proteins. However, MALDI MS has a problem in small molecule (less than 1 kDa) analysis because of the signal saturation by organic matrixes in the low mass region. In imaging MS (IMS), inhomogeneous surface formation due to the co-crystallization process by organic MALDI matrixes limits the spatial resolution of the mass spectral image. Therefore, to make laser desorption/ionization (LDI) MS more suitable for mass spectral profiling and imaging of small molecules directly from raw biological tissues, LDI MS protocols with various alternative assisting materials were developed and applied to many biological systems of interest. Colloidal graphite was used as a matrix for IMS of small molecules for the first time and methodologies for analyses of small metabolites in rat brain tissues, fruits, and plant tissues were developed. With rat brain tissues, the signal enhancement for cerebroside species by colloidal graphite was observed and images of cerebrosides were successfully generated by IMS. In addition, separation of isobaric lipid ions was performed by imaging tandem MS. Directly from Arabidopsis flowers, flavonoids were successfully profiled and heterogeneous distribution of flavonoids in petals was observed for the first time by graphite-assisted LDI(GALDI) IMS.

Thermische Verletzungen im Kindesalter: Eine retrospektive Kohortenstudie von 212 Fällen

OpenAIRE

Sperling, Patrik Leonhart

2012-01-01

Anhand einer retrospektiven Datenanalyse sollen Verteilungsmuster von Verbrennungen und Verbrühungen bezogen auf Alter und Geschlecht untersucht werden. Erfasst wurden 212 Patienten im Alter von 0 bis 16 Jahren betrachtet, die im Zeitraum vom 01.01.2004 bis zum 31.12.2009 auf Grund einer thermischen Verletzung stationär im Universitätsklinikum Würzburg der Julius-Maximilians-Universität Würzburg behandelt wurden. Den größten Anteil thermischer Verletzungen im Kindesalter stellen Verbrühungen ...

Sequence-specific DNA alkylation by tandem Py-Im polyamide conjugates.

Science.gov (United States)

Taylor, Rhys Dylan; Kawamoto, Yusuke; Hashiya, Kaori; Bando, Toshikazu; Sugiyama, Hiroshi

2014-09-01

Tandem N-methylpyrrole-N-methylimidazole (Py-Im) polyamides with good sequence-specific DNA-alkylating activities have been designed and synthesized. Three alkylating tandem Py-Im polyamides with different linkers, which each contained the same moiety for the recognition of a 10 bp DNA sequence, were evaluated for their reactivity and selectivity by DNA alkylation, using high-resolution denaturing gel electrophoresis. All three conjugates displayed high reactivities for the target sequence. In particular, polyamide 1, which contained a β-alanine linker, displayed the most-selective sequence-specific alkylation towards the target 10 bp DNA sequence. The tandem Py-Im polyamide conjugates displayed greater sequence-specific DNA alkylation than conventional hairpin Py-Im polyamide conjugates (4 and 5). For further research, the design of tandem Py-Im polyamide conjugates could play an important role in targeting specific gene sequences. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Information Management System (Ims) For Gender Mainstreaming In ...

African Journals Online (AJOL)

Information Management System (IMS) is an essential tool in supporting the provision of information needed for planning and decision making in any organization. Proper IMS facilitates the smooth flow of information both vertical and horizontal. This paper presents the findings of a survey on information needs of the Gender ...

Intermediate-mass black holes in dwarf galaxies out to redshift ˜ 2.4 in the Chandra COSMOS Legacy Survey

Science.gov (United States)

Mezcua, M.; Civano, F.; Marchesi, S.; Suh, H.; Fabbiano, G.; Volonteri, M.

2018-05-01

We present a sample of 40 AGN in dwarf galaxies at redshifts z ≲ 2.4. The galaxies are drawn from the Chandra COSMOS-Legacy survey as having stellar masses 107 ≤ M* ≤ 3 × 109 M⊙. Most of the dwarf galaxies are star-forming. After removing the contribution from star formation to the X-ray emission, the AGN luminosities of the 40 dwarf galaxies are in the range L0.5-10keV ˜ 1039 - 1044 erg s-1. With 12 sources at z > 0.5, our sample constitutes the highest-redshift discovery of AGN in dwarf galaxies. The record-holder is cid_1192, at z = 2.39 and with L0.5-10keV ˜ 1044 erg s-1. One of the dwarf galaxies has M* = 6.6 × 107 M⊙ and is the least massive galaxy found so far to host an AGN. All the AGN are of type 2 and consistent with hosting intermediate-mass black holes (BHs) with masses ˜104 - 105 M⊙ and typical Eddington ratios >1%. We also study the evolution, corrected for completeness, of AGN fraction with stellar mass, X-ray luminosity, and redshift in dwarf galaxies out to z = 0.7. We find that the AGN fraction for 109 < M* ≤ 3 × 109 M⊙ and LX ˜ 1041 - 1042 erg s-1 is ˜0.4% for z ≤ 0.3 and that it decreases with X-ray luminosity and decreasing stellar mass. Unlike massive galaxies, the AGN fraction seems to decrease with redshift, suggesting that AGN in dwarf galaxies evolve differently than those in high-mass galaxies. Mindful of potential caveats, the results seem to favor a direct collapse formation mechanism for the seed BHs in the early Universe.

Calibración de imágenes de radares meteorológicos

Directory of Open Access Journals (Sweden)

Virgilio Santander Socorras Quintero

2014-04-01

Full Text Available En este documento se ilustran las técnicas de fusión de imágenes para complementar y calibrar la información meteorológica presente en imágenes de radares terrestres con el uso de imágenes satelitales meteorológicas. Para realizar la calibración de las imágenes de radares terrestres se implementó un método de fusión de imágenes basado en la herramienta matemática transformada wavelet discreta. Ya que existe una familia de wavelets, es necesario determinar cuál wavelet ofrece el mejor resultado; para esto se determina la correlación existente entre los resultados de fusión de diferentes wavelets y las imágenes uti-lizadas en cada fusión. Se define una metodología para selección de umbral global de segmentación y una metodología para realizar la calibración de las imágenes de radares terrestres. Siguiendo la metodología de calibración de imágenes, se generan algunos resultados y se muestran sus ventajas.

Measurement of Fragment Mass Distributions in Neutron-induced Fission of {sup 238}U and {sup 232}Th at Intermediate Energies

Energy Technology Data Exchange (ETDEWEB)

Simutkin, V.D. [Uppsala University, P.O Box 525, SE-751 20 Uppsala (Sweden)

2008-07-01

Conceptual analysis of accelerator-driven systems assumes extensive use of nuclear data on neutron-induced reactions at intermediate energies. In particular, information about the fission fragment yields from the {sup 238}U(n,f) and {sup 232}Th(n,f) reactions is of particular interest at neutron energies from 10 to 200 MeV. However, there is a lack of such data for both {sup 238}U and {sup 232}Th. Up to now, the intermediate energy measurements have been performed for {sup 238}U only, and there are no data for the {sup 232}Th(n,f) reaction. The aim of the work is to provide such data. Fission fragment mass distributions for the {sup 232}Th(n,f) and {sup 238}U(n,f) reactions have been measured for the incident neutron energies 32.8 MeV, 45.3 MeV and 59.9 MeV. The experiments have been performed at the neutron beam facility of the Universite Catholique de Louvain, Belgium. A multi-section Frisch-gridded ionization chamber has been used as a fission fragment detector. The data obtained have been interpreted in terms of the multimodal random neck-rupture model (MMRNRM). (authors)

Angular distributions of intermediate mass fragments emitted in 30 MeV/u 40Ar induced reactions

International Nuclear Information System (INIS)

Gou Quanbu; Zhu Yongtai; Xu Hushan; Wei Zhiyong; Lu Jun; Zhang Yuhu; Wang Qi; Li Songlin; Wu Zhongli

1999-01-01

The angular distributions of intermediate mass fragments with charge numbers from 3 to 24 emitted in 30 MeV/u 40 Ar + 58,64 Ni and 115 In reactions over an angular range of 5 degree-140 degree have been measured. In different angular region an exponential distribution function dσ/dΩ = N exp(-θ/α) was used to fit the measured angular distributions. The decay factor α which can be connected with the interaction time τ and the factor N which is related to the intensity of the emission sources have been extracted. The relationship of α(Z) and N(Z) with Z for different reaction systems and different angular regions has been discussed. The different behavior of dσ/dΩ, α(Z), and N(Z) for the three studied reaction systems exists mainly in the middle and backward angular regions. The dependencies of angular distributions on isospin and the size of reaction systems have also been discussed

Modelling of carbonisation of renewable fuels in a rotary kiln reactor; Modellierung der Karbonisierung nachwachsender Rohstoffe im Drehrohrreaktor

Energy Technology Data Exchange (ETDEWEB)

Klose, W; Schinkel, A P [Univ. Kassel (Germany). Inst. fuer Thermische Energietechnik

1998-09-01

The contribution models the pyrolysis of corn in a rotary kiln reactor. The model comprises a solution of the two-dimensional energy and mass balances for the solid phase. The movement of the solid matter inside the reactor is described by model equations. The influence of various operating parameters on the pyrolysis process is discussed, i.e. temperature, rotational speed, length and angle of inclination of the tube. (orig.) [Deutsch] In diesem Beitrag wird die Pyrolyse von Mais im Drehrohrreaktor modelliert. Das Modell beinhaltet die Loesung der 2dimensionalen Energie- und Stoffbilanzen fuer die feste Phase. Die Gutbewegung im Drehrohr wird mit Hilfe von Modellansaetzen beschrieben. Es wird der Einfluss der Betriebsparameter Temperatur, Drehzahl, Laenge und Neigungswinkel des Rohres auf die Pyrolyse diskutiert. (orig.)

ABSOLUTE DIMENSIONS OF THE G7+K7 ECLIPSING BINARY STAR IM VIRGINIS: DISCREPANCIES WITH STELLAR EVOLUTION MODELS

International Nuclear Information System (INIS)

Morales, Juan Carlos; Torres, Guillermo; Marschall, Laurence A.; Brehm, William

2009-01-01

We report extensive spectroscopic and differential photometric BVRI observations of the active, detached, 1.309-day double-lined eclipsing binary IM Vir, composed of a G7-type primary and a K7 secondary. With these observations, we derive accurate absolute masses and radii of M 1 = 0.981 ± 0.012 M sun , M 2 = 0.6644 ± 0.0048 M sun , R 1 = 1.061 ± 0.016 R sun , and R 2 = 0.681 ± 0.013 R sun for the primary and secondary, with relative errors under 2%. The effective temperatures are 5570 ± 100 K and 4250 ± 130 K, respectively. The significant difference in mass makes this a favorable case for comparison with stellar evolution theory. We find that both stars are larger than the models predict, by 3.7% for the primary and 7.5% for the secondary, as well as cooler than expected, by 100 K and 150 K, respectively. These discrepancies are in line with previously reported differences in low-mass stars, and are believed to be caused by chromospheric activity, which is not accounted for in current models. The effect is not confined to low-mass stars: the rapidly rotating primary of IM Vir joins the growing list of objects of near-solar mass (but still with convective envelopes) that show similar anomalies. The comparison with the models suggests an age of 2.4 Gyr for the system, and a metallicity of [Fe/H] ∼-0.3 that is consistent with other indications, but requires confirmation.

Choosing the Right Free IM Providers and Clients for Your Library

Science.gov (United States)

Izenstark, Amanda K.

2009-01-01

With virtual library services increasing, public services librarians may find themselves with questions such as: What instant messaging services (IM) are available? Which IM service would best suit my patrons' needs? Which IM service best suits my library's technology profile? This column describes the features and functionality of major instant…

World-wide developments in motor vehicle inspection/maintenance (I/M) programs

Energy Technology Data Exchange (ETDEWEB)

Klausmeier, R. [Consulting Inc., Austin, TX (United States); Kishan, S. [Radian Corporation, Austin, TX (United States)

1995-12-31

Motor vehicles contribute much to urban air pollution. As a result, most governments have enacted emission standards that significantly lower pollutant emission levels from new motor vehicles. For example, vehicles built in the United States emit 95 % fewer pollutants than uncontrolled vehicles when they are new. However, studies indicate that proper maintenance is needed to obtain the full benefit of vehicle emission controls. Furthermore, there is evidence that a significant percentage of the vehicle fleet is not properly maintained. This has led to the creation of motor vehicle Inspection/Maintenance (I/M) Programs. I/M programs inspect vehicles for indications that they are emitting excessive quantities of pollutants. Vehicles that fail the inspection must be repaired in order to comply with program requirements. The first I/M programs were implemented in the United States in the early 1970s. With substantial urging from the federal government, most of the U.S. states with severe air pollution problems have implemented I/M programs. Recently, with the passage of the U.S. Clean Air Act Amendments of 1990, many states have been required to significantly upgrade the performance and coverage of their I/M programs. I/M programs also have been implemented in Europe and recently in Asia. This presentation reviews developments in I/M programs for light-duty gasoline powered vehicles. Developments in I/M programs for diesel powered vehicles are briefly described. (author)

World-wide developments in motor vehicle inspection/maintenance (I/M) programs

Energy Technology Data Exchange (ETDEWEB)

Klausmeier, R [Consulting Inc., Austin, TX (United States); Kishan, S [Radian Corporation, Austin, TX (United States)

1996-12-31

Motor vehicles contribute much to urban air pollution. As a result, most governments have enacted emission standards that significantly lower pollutant emission levels from new motor vehicles. For example, vehicles built in the United States emit 95 % fewer pollutants than uncontrolled vehicles when they are new. However, studies indicate that proper maintenance is needed to obtain the full benefit of vehicle emission controls. Furthermore, there is evidence that a significant percentage of the vehicle fleet is not properly maintained. This has led to the creation of motor vehicle Inspection/Maintenance (I/M) Programs. I/M programs inspect vehicles for indications that they are emitting excessive quantities of pollutants. Vehicles that fail the inspection must be repaired in order to comply with program requirements. The first I/M programs were implemented in the United States in the early 1970s. With substantial urging from the federal government, most of the U.S. states with severe air pollution problems have implemented I/M programs. Recently, with the passage of the U.S. Clean Air Act Amendments of 1990, many states have been required to significantly upgrade the performance and coverage of their I/M programs. I/M programs also have been implemented in Europe and recently in Asia. This presentation reviews developments in I/M programs for light-duty gasoline powered vehicles. Developments in I/M programs for diesel powered vehicles are briefly described. (author)

Respuestas faciales ante imágenes de advertencia de tabaco

Directory of Open Access Journals (Sweden)

M. A. Muñoz

Full Text Available Resumen En 2003, la Comisión Europea propuso una serie de advertencias visuales para ser incluidas en los embalajes de tabaco, con el objetivo de motivar a los fumadores a dejar de fumar y promover actitudes negativas hacia el tabaco. El objetivo de este estudio fue evaluar el impacto de las advertencias sanitarias mediante autoinformes y medidas psicofisiológicas. Cincuenta sujetos sanos (19-23 años visionaron un conjunto de treinta y seis imágenes de diferente contenido emocional y veinticuatro del banco de imágenes preventivas propuestas por la Comisión Europea. Se registró la actividad eléctrica de los músculos cigomático mayor y corrugador mientras los sujetos visionaban estas imágenes. A continuación, los participantes evaluaban las imágenes en las dimensiones de agradabilidad y activación. Los resultados muestran una mayor actividad eléctrica del musculo corrugador ante la presentación de imágenes desagradables comparadas con advertencias desagradables incluidas en los paquetes de tabaco. Estos resultados sugieren que la campaña preventiva podría beneficiarse de imágenes preventivas más impactantes, promoviendo así la activación del sistema motivacional evitativo/defensivo.

The environmental and radionuclide laboratory at VKTA Rossendorf; Das Labor fuer Umwelt- und Radionuklidanalytik im VKTA Rossendorf

Energy Technology Data Exchange (ETDEWEB)

Koehler, M.; Knappik, R.; Gleisberg, B.; Schaefer, I.; Boden, W.; Bothe, M. [Verein fuer Kernverfahrenstechnik und Analytik Rossendorf e.V. (VKTA), Dresden (Germany)

2001-07-01

The VKTA provides environmental and radionuclide analyses for remediation and waste management tasks at the Rossendorf research site and for commercial clients as well. The analyses, the correlated valuations and calculations were used for the decommissioning of nuclear facilities, for the remediation of contaminated mining sites and for environmental investigations. The Laboratory for Environmental and Radionuclide Analytics is able to handle and analyse artificial and natural radionuclides in the range from 10{sup -3} Bq until 10{sup 9} Bq. Besides the used activity measurement techniques ({alpha}-particle and {gamma}-ray spectrometry, {beta}-counting), which were also applied after radiochemical separations, mass-spectrometry with inductively coupled plasma provides analytical results for long-lived radionuclides and isotopic ratios very effective. The capability of the laboratory is demonstrated by selected applications. (orig.) [German] Der VKTA fuehrt im Rahmen seiner Rueckbau- und Entsorgungsaufgaben am Forschungsstandort Rossendorf und fuer externe Auftraggeber Umwelt- und Radionuklidanalysen als komplexe Dienstleistung durch. Die Analysen und die damit in Zusammenhang stehenden Bewertungen und Modellrechnungen finden beim Rueckbau kerntechnischer Anlagen, bei der Sanierung von Uranbergbau-Altlasten und im Umweltbereich Verwendung. Im Labor fuer Umwelt- und Radionuklidanalytik werden Proben mit kuenstlichen und natuerlichen Radionukliden im typischen Aktivitaetsbereich von 10{sup -3} Bq bis 10{sup 9} Bq bearbeitet und analysiert. Neben den Aktivitaetsmessverfahren ({alpha}-, {beta}-, {gamma}-Spektrometrie), die auch nach radiochemischen Trennungen eingesetzt werden, kommen massenspektrometrische Verfahren bei der Analyse langlebiger Radionuklide bzw. Isotopenverhaeltnisse zum Einsatz. Das Leistungsspektrum des Labors wird durch ausgewaehlte Applikationen belegt. (orig.)

Profiling the indole alkaloids in yohimbe bark with ultra-performance liquid chromatography coupled with ion mobility quadrupole time-of-flight mass spectrometry.

Science.gov (United States)

Sun, Jianghao; Baker, Andrew; Chen, Pei

2011-09-30

An ultra-performance liquid chromatography/ion mobility quadrupole time-of-flight mass spectrometry (UPLC/IM-QTOF-MS) method was developed for profiling the indole alkaloids in yohimbe bark. Many indole alkaloids with the yohimbine or ajmalicine core structure, plus methylated, oxidized and reduced species, were characterized. Common fragments and mass differences are described. It was shown that the use of IMS could provide another molecular descriptor, i.e. molecular shape by rotationally averaged collision cross-section; this is of great value for identification of constituents when reference materials are usually not available. Using the combination of high resolution (~40000) accurate mass measurement with time-aligned parallel (TAP) fragmentation, MS(E) (where E represents collision energy), ion mobility mass spectrometry (IMS) and UPLC chromatography, a total 55 indole alkaloids were characterized and a few new indole alkaloids are reported for the first time. Published in 2011 by John Wiley & Sons, Ltd.

The double-degenerate model for the progenitors of Type Ia supernovae

Science.gov (United States)

Liu, D.; Wang, B.; Han, Z.

2018-02-01

The double-degenerate (DD) model, involving the merging of massive double carbon-oxygen white dwarfs (CO WDs) driven by gravitational wave radiation, is one of the classical pathways for the formation of Type Ia supernovae (SNe Ia). Recently, it has been proposed that the WD+He subgiant channel has a significant contribution to the production of massive double WDs, in which the primary WD accumulates mass by accreting He-rich matter from an He subgiant. We evolved about 1800 CO WD+He star systems and obtained a large and dense grid for producing SNe Ia through the DD model. We then performed a series of binary population synthesis simulations for the DD model, in which the WD+He subgiant channel is calculated by interpolations in the SN Ia production grid. According to our standard model, the Galactic birth rate of SNe Ia is about 2.4 × 10- 3 yr- 1 for the WD+He subgiant channel of the DD model; the total birth rate is about 3.7 × 10- 3 yr- 1 for all channels, reproducing that of observations. Previous theoretical models still have deficit with the observed SNe Ia with delay times 8 Gyr. After considering the WD+He subgiant channel, we found that the delay time distributions are comparable with the observed results. Additionally, some recent studies proposed that the violent WD mergers are more likely to produce SNe Ia based on the DD model. We estimated that the violent mergers through the DD model may contribute to at most 16 per cent of all SNe Ia.

Jung und Alt im Dialog

Directory of Open Access Journals (Sweden)

Caroline Baetge

2012-04-01

Full Text Available Rezension zu: Kupser, Thomas, und Ida Pöttinger, Hrsg. 2011. Mediale Brücken: Generationen im Dialog durch aktive Medienarbeit. Gesellschaft - Altern - Medien 3. München: kopaed.

Developing an effective IM/IT strategy.

Science.gov (United States)

Kramer, Sarah; Walker, Joanne; Falk, Will

2009-01-01

Healthcare organizations and systems around the world lag far behind banking, manufacturing, travel and other industries in their use of information management/information technology (IM/IT) to deliver high-quality products and services. Across Canada, healthcare organizations, as well as governments, understand that information and information technology are needed to deliver quality care and to sustain our publicly funded health system. However, insufficient funding, few experienced resources, lack of strong leadership and absence of clear business/clinical rationale have restricted innovation and advancement in the use of IM/IT to improve healthcare delivery and patient outcomes.

Real-time resource availability signalling in IMS-based networks

NARCIS (Netherlands)

Ozcelebi, T.; Radovanovic, I.; Lukkien, J.J.

2007-01-01

The emerging converged IP multimedia subsystem (IMS) allows the use of unlicensed, nondedicated and nondeterministic computer access networks for delivering IP multimedia services. To provide end-to-end quality-of-service (QoS) over such networks combined with the IMS core network, for resource

Reactive intermediates in the gas phase generation and monitoring

CERN Document Server

Setser, D W

2013-01-01

Reactive Intermediates in the Gas Phase: Generation and Monitoring covers methods for reactive intermediates in the gas phase. The book discusses the generation and measurement of atom and radical concentrations in flow systems; the high temperature flow tubes, generation and measurement of refractory species; and the electronically excited long-lived states of atoms and diatomic molecules in flow systems. The text also describes the production and detection of reactive species with lasers in static systems; the production of small positive ions in a mass spectrometer; and the discharge-excite

Medida Interpessoal de Psicopatia (IM-P: estudo preliminar no contexto brasileiro Interpersonal Measure of Psychopathy (IM-P: preliminary study in the Brazilian context

Directory of Open Access Journals (Sweden)

Tárcia Rita Davoglio

2011-01-01

Full Text Available INTRODUÇÃO: A observação direta do comportamento interpessoal é um recurso importante na descrição e diagnóstico da personalidade psicopática. A Medida Interpessoal de Psicopatia (Interpersonal Measure of Psychopathy, IM-P é um instrumento psicométrico composto por 21 itens, desenvolvido para ser utilizado em associação com outras escalas de avaliação da psicopatia. Foca-se, especificamente, nos comportamentos interpessoais e aspectos não verbais evidentes na interação do entrevistador com indivíduos que apresentam características psicopáticas. OBJETIVO: Descrever resultados preliminares sobre a investigação de aspectos interpessoais da psicopatia mediante a utilização da IM-P, incluindo as etapas de tradução/adaptação e avaliação de confiabilidade interavaliadores da IM-P, em uma amostra de adolescentes brasileiros. MÉTODO: Trata-se de estudo transversal, descritivo e correlacional realizado com 20 adolescentes masculinos cumprindo medida socioeducativa com privação de liberdade na Região Metropolitana de Porto Alegre (RS. Após os procedimentos de tradução da escala, treinamento dos pesquisadores e teste piloto por meio de uma entrevista semiestruturada, a IM-P foi pontuada por três juízes independentes. RESULTADOS: Os resultados estatísticos, obtidos através do coeficiente de concordância de Kendall, revelaram grau de concordância interavaliadores elevado e satisfatório para os escores totais da IM-P (W = 0,84; p INTRODUCTION: The direct observation of interpersonal behaviors is an important resource in the description and diagnosis of the psychopathic personality. The Interpersonal Measure of Psychopathy (IM-P is a psychometric instrument comprised of 21 items, designed to be applied in association with other instruments that also evaluate psychopaths. It focuses specifically on interpersonal and non-verbal behaviors that become evident during the interaction between the interviewer and individuals

Hot Jupiters and cool stars

International Nuclear Information System (INIS)

Villaver, Eva; Mustill, Alexander J.; Livio, Mario; Siess, Lionel

2014-01-01

Close-in planets are in jeopardy, as their host stars evolve off the main sequence (MS) to the subgiant and red giant phases. In this paper, we explore the influences of the stellar mass (in the range 1.5-2 M ☉ ), mass-loss prescription, planet mass (from Neptune up to 10 Jupiter masses), and eccentricity on the orbital evolution of planets as their parent stars evolve to become subgiants and red giants. We find that planet engulfment along the red giant branch is not very sensitive to the stellar mass or mass-loss rates adopted in the calculations, but quite sensitive to the planetary mass. The range of initial separations for planet engulfment increases with decreasing mass-loss rates or stellar masses and increasing planetary masses. Regarding the planet's orbital eccentricity, we find that as the star evolves into the red giant phase, stellar tides start to dominate over planetary tides. As a consequence, a transient population of moderately eccentric close-in Jovian planets is created that otherwise would have been expected to be absent from MS stars. We find that very eccentric and distant planets do not experience much eccentricity decay, and that planet engulfment is primarily determined by the pericenter distance and the maximum stellar radius.

Address Translation Problems in IMS Based Next Generation Networks

Directory of Open Access Journals (Sweden)

Balazs Godor

2006-01-01

Full Text Available The development of packed based multimedia networks reached a turning point when the ITU-T and the ETSIhave incorporated the IMS to the NGN. With the fast development of mobile communication more and more services andcontent are available. In contrast with fix network telephony both the services and the devices are personalized in the “mobileworld”. Services, known from the Internet - like e-mail, chat, browsing, presence, etc. – are already available via mobiledevices as well. The IMS originally wanted to exploit both the benefits of mobile networks and the fancy services of theInternet. But today it is already more than that. IMS is the core of the next generation telecommunication networks and abasis for fix-mobile convergent services. The fact however that IMS was originally a “mobile” standard, where IPv6 was notoddity generated some problems for the fix networks, where IPv4 is used. In this article I give an overview of these problemsand mention some solutions as well.

Systems and methods for integrating ion mobility and ion trap mass spectrometers

Science.gov (United States)

Ibrahim, Yehia M.; Garimella, Sandilya; Prost, Spencer A.

2018-04-10

Described herein are examples of systems and methods for integrating IMS and MS systems. In certain examples, systems and methods for decoding double multiplexed data are described. The systems and methods can also perform multiple refining procedures in order to minimize the demultiplexing artifacts. The systems and methods can be used, for example, for the analysis of proteomic and petroleum samples, where the integration of IMS and high mass resolution are used for accurate assignment of molecular formulae.

Transport and transformation of surface water masses across the ...

African Journals Online (AJOL)

Transport and transformation of surface water masses across the Mascarene Plateau during the Northeast Monsoon season. ... Mixing occurs in the central gap between intermediate water masses (Red Sea Water [RSW] and Antarctic Intermediate Water [AAIW]) as well as in the upper waters (Subtropical Surface Water ...

Imaging mass spectrometry in papillary thyroid carcinoma for the identification and validation of biomarker proteins.

Science.gov (United States)

Min, Kyueng-Whan; Bang, Joo-Young; Kim, Kwang Pyo; Kim, Wan-Seop; Lee, Sang Hwa; Shanta, Selina Rahman; Lee, Jeong Hwa; Hong, Ji Hye; Lim, So Dug; Yoo, Young-Bum; Na, Chan-Hyun

2014-07-01

Direct tissue imaging mass spectrometry (IMS) by matrix-assisted laser desorption ionization and time-of-flight (MALDI-TOF) mass spectrometry has become increasingly important in biology and medicine, because this technology can detect the relative abundance and spatial distribution of interesting proteins in tissues. Five thyroid cancer samples, along with normal tissue, were sliced and transferred onto conductive glass slides. After laser scanning by MALDI-TOF equipped with a smart beam laser, images were created for individual masses and proteins were classified at 200-µm spatial resolution. Based on the spatial distribution, region-specific proteins on a tumor lesion could be identified by protein extraction from tumor tissue and analysis using liquid chromatography with tandem mass spectrometry (LC-MS/MS). Using all the spectral data at each spot, various intensities of a specific peak were detected in the tumor and normal regions of the thyroid. Differences in the molecular weights of expressed proteins between tumor and normal regions were analyzed using unsupervised and supervised clustering. To verify the presence of discovered proteins through IMS, we identified ribosomal protein P2, which is specific for cancer. We have demonstrated the feasibility of IMS as a useful tool for the analysis of tissue sections, and identified the tumor-specific protein ribosomal protein P2.

Does Explosive Nuclear Burning Occur in Tidal Disruption Events of White Dwarfs by Intermediate-mass Black Holes?

Energy Technology Data Exchange (ETDEWEB)

Tanikawa, Ataru; Sato, Yushi; Hachisu, Izumi [Department of Earth Science and Astronomy, College of Arts and Sciences, The University of Tokyo, 3-8-1 Komaba, Meguro-ku, Tokyo 153-8902 (Japan); Nomoto, Ken’ichi; Maeda, Keiichi [Kavli Institute for the Physics and Mathematics of the Universe (WPI), The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8583 (Japan); Nakasato, Naohito, E-mail: tanikawa@ea.c.u-tokyo.ac.jp [Department of Computer Science and Engineering, University of Aizu, Tsuruga Ikki-machi Aizu-Wakamatsu, Fukushima 965-8580 (Japan)

2017-04-20

We investigate nucleosynthesis in tidal disruption events (TDEs) of white dwarfs (WDs) by intermediate-mass black holes. We consider various types of WDs with different masses and compositions by means of three-dimensional (3D) smoothed particle hydrodynamics (SPH) simulations. We model these WDs with different numbers of SPH particles, N , from a few 10{sup 4} to a few 10{sup 7} in order to check mass resolution convergence, where SPH simulations with N > 10{sup 7} (or a space resolution of several 10{sup 6} cm) have unprecedentedly high resolution in this kind of simulation. We find that nuclear reactions become less active with increasing N and that these nuclear reactions are excited by spurious heating due to low resolution. Moreover, we find no shock wave generation. In order to investigate the reason for the absence of a shock wave, we additionally perform one-dimensional (1D) SPH and mesh-based simulations with a space resolution ranging from 10{sup 4} to 10{sup 7} cm, using a characteristic flow structure extracted from the 3D SPH simulations. We find shock waves in these 1D high-resolution simulations, one of which triggers a detonation wave. However, we must be careful of the fact that, if the shock wave emerged in an outer region, it could not trigger the detonation wave due to low density. Note that the 1D initial conditions lack accuracy to precisely determine where a shock wave emerges. We need to perform 3D simulations with ≲10{sup 6} cm space resolution in order to conclude that WD TDEs become optical transients powered by radioactive nuclei.

Gesundheit und Pflege im Alter

OpenAIRE

Pfaff, Martin

1989-01-01

Gesundheit und Pflege im Alter : d. Gesundheitsreformgesetz (GRG) ; Möglichkeiten, Grenzen u. weitere Vorschläge / Martin Pfaff ; Klaus Deimer. - In: Expertengespräch "Pflege in der Familie". - Augsburg, 1989. - Getr. Zählung

Towards a dynamical description of intermediate mass fragment formation in heavy-ion collisions at some tens of MeV/A

International Nuclear Information System (INIS)

Suraud, E.

1990-01-01

We briefly remind the possible dynamical scenario of fragments formation in central heavy-ion collisions at some tens of MeV/A. We discuss how present day dynamical models can describe fragment formation. We show that particle methods provide a reasonable solution of Boltzman-like equations. We next turn to the Boltzmann-Langevin formalism which gives a well defined framework for the understanding of Intermediate Mass Fragments formation. We present a first numerical solution of this equation and show the importance of fluctuations in the dynamics of the collision. We finally apply the formalism to the onset of multifragmentation in the 40 Ca + 40 Ca system between 20 and 60 MeV/A beam energy

Digitalisierung im Verteilnetz: Evolution oder Revolution anhand konkreter Beispiele

Science.gov (United States)

Krone, Oliver; Bachmann, Maurus

Durch die Integration der neuen erneuerbaren Energien steht das Stromnetz vor großen Herausforderungen. Das Energiesystem als Gesamtes und die Verteilnetze im Speziellen werden smart. Anhand konkreter Beispiele wird aufgezeigt, wie die Digitalisierung im Elektrizitätsnetz voranschreitet. Diese Entwicklung ist eine Evolution, nicht aber eine Revolution.

Integrated municipal wind power concepts; Windenergienutzung im staedtischen Verbund

Energy Technology Data Exchange (ETDEWEB)

Kolbert, D.; Richert, F. [Ventis Energietechnik GmbH, Braunschweig (Germany)

1998-06-01

The role of wind power in the industrial sector currently depends very much on its technical and economic integrability in existing conventional supply structures. The most important questions in this context relate to capacity effects, adapted operating methods of conventional power suppliers, and, most important of all, operational energy production costs. In some regions alternative energy supply concepts are not yet or not sufficiently available. However, these will nevertheless offer ways of installing energy systems with a large renewable segment. The chances of bringing such projects to fruition depend for one thing on the climate, which may either stimulate or deter from development work on renewables (wind power, solar energy), and for another, often in apparent opposition to the former, on the oftentimes poorly developed infrastructure and economic strength of the region in question. [Deutsch] Die Bedeutung der Windenergienutzung im industrialisierten Bereich ist derzeit verknuepft mit deren technischen und oekonomischen Integrationsfaehigkeit in bestehende, konventionelle Versorgungsstrukturen. Im Vordergrund steht hierbei die Klaerung der Fragestellungen nach Kapazitaetseffekten, angepassten Betriebsweisen konventioneller Stromerzeuger und, in erster Linie, betriebswirtschaftlichen Energieerzeugungskosten. Derzeit bieten die Regionen, in denen eine anderweitige Versorgung noch nicht oder in nicht ausreichendem Masse existieren Moeglichkeiten zur Installation von Energiesystemen mit hoher regenerativer Durchdringung. Fuer die Realisation solcher Projekte stehen sich haeufig die klimatischen Bedingungen, die einerseits z.T. die Ursache fuer den geringen Entwicklungsstand sind, andererseits aber auch guenstige Voraussetzungen fuer die Nutzung regenerativer Energien (Wind, Sonne) bieten, der meist schlechten Infrastruktur und der geringen Wirtschaftskraft gegenueber. (orig./MSK)

Experimental determination of primary and intermediate ions in a flame front

Energy Technology Data Exchange (ETDEWEB)

Fialkov, A.B.; Fialkov, B.S.

1988-10-01

A procedure is described for determining the primary and intermediate ions in the front of a flame rarefied using mass spectrometry. By using the method proposed here, primary CHO(+) and CHO2(+) ions as well as a series of short-lived intermediate ions have been identified. The possibility of using this method for obtaining quantitative data on the characteristic lifetimes of ions and rate constants of ion-molecular reactions in flames is demonstrated. 16 references.

Review of Global Ocean Intermediate Water Masses: 1.Part A,the Neutral Density Surface (the 'McDougall Surface') as a Study Frame for Water-Mass Analysis

Institute of Scientific and Technical Information of China (English)

Yuzhu You

2006-01-01

This review article commences with a comprehensive historical review of the evolution and application of various density surfaces in atmospheric and oceanic studies.The background provides a basis for the birth of the neutral density idea.Attention is paid to the development of the neutral density surface concept from the nonlinearity of the equation of state of seawater.The definition and properties of neutral density surface are described in detail as developed from the equations of state of seawater and the buoyancy frequency when the squared buoyancy frequency N2 is zero, a neutral state of stability.In order to apply the neutral density surface to intermediate water-mass analysis, this review also describes in detail its practical oceanographic application.The mapping technique is focused for the first time on applying regularly gridded data in this review.It is reviewed how a backbone and ribs framework was designed to flesh out from a reference cast and first mapped the global neutral surfaces in the world's oceans.Several mapped neutral density surfaces are presented as examples for each world ocean.The water-mass property is analyzed in each ocean at mid-depth.The characteristics of neutral density surfaces are compared with those of potential density surfaces.

Aggregation und Management von Metadaten im Kontext von Europeana

Directory of Open Access Journals (Sweden)

Gerda Koch

2017-09-01

Full Text Available Mit dem In-Beziehung-Setzen und Verlinken von Daten im Internet wird der Weg zur Umsetzung des semantischen Webs geebnet. Erst die semantische Verbindung von heterogenen Datenbeständen ermöglicht übergreifende Suchvorgänge und späteres „Machine Learning“. Im Artikel werden die Aktivitäten der Europäischen Digitalen Bibliothek im Bereich des Metadatenmanagements und der semantischen Verlinkung von Daten skizziert. Dabei wird einerseits ein kurzer Überblick zu aktuellen Forschungsschwerpunkten und Umsetzungsstrategien gegeben, und darüber hinaus werden einzelne Projekte und maßgeschneiderte Serviceangebote für naturhistorische Daten, regionale Kultureinrichtungen und Audiosammlungen beschrieben.

Dynamics of light, intermediate, heavy and superheavy nuclear ...

Indian Academy of Sciences (India)

2014-05-01

May 1, 2014 ... Various features related to the dynamics of competing decay modes of nuclear systems are explored by addressing the experimental data of a number of reactions in light, intermediate, heavy and superheavy mass regions. The DCM, being a non-statistical description for the decay of a com- pound nucleus ...

Sexting im Schulumfeld

Directory of Open Access Journals (Sweden)

Barbara Buchegger

2015-03-01

Full Text Available Wir wollten es einfach wissen. Wie steht es nun mit diesem "Sexting" – also der Übermittlung von Nacktaufnahmen, die Jugendliche untereinander teilen? Stimmt unser Eindruck aus den Workshops in Schulen, dass es bereits ein "übliches Verhalten" der Jugendlichen geworden ist? Saferinternet.at hat im November/Dezember 2014 eine Studie durch das Institut für Jugendkulturforschung rund um das Thema "Sexting" in Auftrag gegeben.

N-body modeling of globular clusters: detecting intermediate-mass black holes by non-equipartition in HST proper motions

Science.gov (United States)

Trenti, Michele

2010-09-01

Intermediate Mass Black Holes {IMBHs} are objects of considerable astrophysical significance. They have been invoked as possible remnants of Population III stars, precursors of supermassive black holes, sources of ultra-luminous X-ray emission, and emitters of gravitational waves. The centers of globular clusters, where they may have formed through runaway collapse of massive stars, may be our best chance of detecting them. HST studies of velocity dispersions have provided tentative evidence, but the measurements are difficult and the results have been disputed. It is thus important to explore and develop additional indicators of the presence of an IMBH in these systems. In a Cycle 16 theory project we focused on the fingerprints of an IMBH derived from HST photometry. We showed that an IMBH leads to a detectable quenching of mass segregation. Analysis of HST-ACS data for NGC 2298 validated the method, and ruled out an IMBH of more than 300 solar masses. We propose here to extend the search for IMBH signatures from photometry to kinematics. The velocity dispersion of stars in collisionally relaxed stellar systems such as globular clusters scales with main sequence mass as sigma m^alpha. A value alpha = -0.5 corresponds to equipartition. Mass-dependent kinematics can now be measured from HST proper motion studies {e.g., alpha = -0.21 for Omega Cen}. Preliminary analysis shows that the value of alpha can be used as indicator of the presence of an IMBH. In fact, the quenching of mass segregation is a result of the degree of equipartition that the system attains. However, detailed numerical simulations are required to quantify this. Therefore we propose {a} to carry out a new, larger set of realistic N-body simulations of star clusters with IMBHs, primordial binaries and stellar evolution to predict in detail the expected kinematic signatures and {b} to compare these predictions to datasets that are {becoming} available. Considerable HST resources have been invested in

Oxidative demethylation of lanosterol in cholesterol biosynthesis: accumulation of sterol intermediates

International Nuclear Information System (INIS)

Shafiee, A.; Trzaskos, J.M.; Paik, Y.K.; Gaylor, J.L.

1986-01-01

With [ 3 H-24,25]-dihydrolanosterol as substrate, large-scale metabolic formation of intermediates of lanosterol demethylation was carried out to identify all compounds in the metabolic process. Utilizing knowledge of electron transport of lanosterol demethylation, we interrupted the demethylation reaction allowing accumulation and confirmation of the structure of the oxygenated intermediates lanost-8-en-3 beta,32-diol and 3 beta-hydroxylanost-8-en-32-al, as well as the demethylation product 4,4-dimethyl-cholesta-8,14-dien-3 beta-ol. Further metabolism of the delta 8.14-diene intermediate to a single product 4,4-dimethyl-cholest-8-en-3 beta-ol occurs under interruption conditions in the presence of 0.5 mM CN-1. With authentic compounds, each intermediate has been rigorously characterized by high performance liquid chromatography and gas-liquid chromatography plus mass spectral analysis of isolated and derivatized sterols. Intermediates that accumulated in greater abundance were further characterized by ultraviolet, 1 H-NMR, and infrared spectroscopy of the isolated sterols

A two-stage extraction procedure for insensitive munition (IM) explosive compounds in soils.

Science.gov (United States)

Felt, Deborah; Gurtowski, Luke; Nestler, Catherine C; Johnson, Jared; Larson, Steven

2016-12-01

The Department of Defense (DoD) is developing a new category of insensitive munitions (IMs) that are more resistant to detonation or promulgation from external stimuli than traditional munition formulations. The new explosive constituent compounds are 2,4-dinitroanisole (DNAN), nitroguanidine (NQ), and nitrotriazolone (NTO). The production and use of IM formulations may result in interaction of IM component compounds with soil. The chemical properties of these IM compounds present unique challenges for extraction from environmental matrices such as soil. A two-stage extraction procedure was developed and tested using several soil types amended with known concentrations of IM compounds. This procedure incorporates both an acidified phase and an organic phase to account for the chemical properties of the IM compounds. The method detection limits (MDLs) for all IM compounds in all soil types were regulatory risk-based Regional Screening Level (RSL) criteria for soil proposed by the U.S. Army Public Health Center. At defined environmentally relevant concentrations, the average recovery of each IM compound in each soil type was consistent and greater than 85%. The two-stage extraction method decreased the influence of soil composition on IM compound recovery. UV analysis of NTO established an isosbestic point based on varied pH at a detection wavelength of 341 nm. The two-stage soil extraction method is equally effective for traditional munition compounds, a potentially important point when examining soils exposed to both traditional and insensitive munitions. Copyright © 2016 Elsevier Ltd. All rights reserved.

Medienpädagogische Aufgabenfelder hinsichtlich der Visualität im digitalen Zeitalter. Desiderate im Umgang mit visuellen Medienkulturen

Directory of Open Access Journals (Sweden)

Petra Missomelius

2017-04-01

Full Text Available Die bildungskulturell leitende Funktion des Buches diffundiert im digitalen Zeitalter mobiler und transversaler Systeme von Netzwerkmedien. Zudem sind soziokulturelle Lebenswelten wie Bildungsinstitutionen, Familie und Peers durch Heterogenität gekennzeichnet. Indem auch diese Teil des Geflechts medienkultureller Architekturen werden, geraten ehemals gültige Unterscheidungsparameter wie explizites und implizites, formelles und informelles Wissen ins Wanken. Grenzziehungen und konkurrierende Auffassungen gegenüber diesen, vormals als der Bildung entgegengesetzt wahrgenommenen, Bereichen erweisen sich nunmehr als problematisch. So spielt Visualität im Kontext multimodal zusammengesetzter Bildungsmaterialien eine zunehmende Rolle und wird als Möglichkeit des Umgangs mit Komplexität eingesetzt. Wenngleich somit die Zurückhaltung gegenüber (Bewegt-Bildmedien in der pädagogischen Praxis schwindet, so haben sich mit der Digitalisierung medienkulturell bedeutsame Felder eröffnet, welche erziehungswissenschaftlicher Beachtung bedürfen. Eine sich der Komplexität digitaler Medienkulturen stellende Medienpädagogik bringt mit sich, dass auch Funktion und Gebrauch visueller Medien im Kontext von Bildungsprozessen reflektiert stattfinden. Medienpädagogisch informiertes Agieren in visuellen Medienkulturen ist darüber hinaus heute gerade deshalb essentiell, da es sich bei digital generierter Visualität um eine neue Qualität im Unterschied zu traditionellen Bildmedien handelt, welche der Logik der Repräsentation entsprachen. Der Beitrag thematisiert Desiderate, die sich hinsichtlich des Visuellen datenbasierter Medien für die Medienpädagogik ergeben, und geht dabei auf kommunikative Bildlichkeit, auf paradigmatische mediale Formen und auf datengestützte Wissensgenerierung ein.

Model of cosmology and particle physics at an intermediate scale

International Nuclear Information System (INIS)

Bastero-Gil, M.; Di Clemente, V.; King, S. F.

2005-01-01

We propose a model of cosmology and particle physics in which all relevant scales arise in a natural way from an intermediate string scale. We are led to assign the string scale to the intermediate scale M * ∼10 13 GeV by four independent pieces of physics: electroweak symmetry breaking; the μ parameter; the axion scale; and the neutrino mass scale. The model involves hybrid inflation with the waterfall field N being responsible for generating the μ term, the right-handed neutrino mass scale, and the Peccei-Quinn symmetry breaking scale. The large scale structure of the Universe is generated by the lightest right-handed sneutrino playing the role of a coupled curvaton. We show that the correct curvature perturbations may be successfully generated providing the lightest right-handed neutrino is weakly coupled in the seesaw mechanism, consistent with sequential dominance

IMS Intra- and Inter Domain End-to-End Resilience Analysis

DEFF Research Database (Denmark)

Kamyod, Chayapol; Nielsen, Rasmus Hjorth; Prasad, Neeli R.

2013-01-01

This paper evaluated resilience of the reference IMS based network topology in operation through the keys reliability parameters via OPNET. The reliability behaviors of communication within similar and across registered home IMS domains were simulated and compared. Besides, the reliability effects...

EFEKTIVITAS MEDIA PEMBELAJARAN IM3 DITINJAU DARI MOTIVASI BELAJAR

Directory of Open Access Journals (Sweden)

J. Handhika

2012-10-01

Full Text Available Penelitian ini bertujuan untuk mengetahui perbedaan penggunaan media pembelajaran IM3 berbasis flash dan media MS. Power Point terhadap prestasi belajar IPA-Fisika. Hasil penelitian  menunjukkan bahwa siswa yang diajar menggunakan media IM3 berbasis flash memberikan rata-rata prestasi lebih baik dibandingkan dengan siswa yang diajar menggunakan power point. Siswa dengan motivasi belajar tinggi menghasilkan rata-rata prestasi lebih baik daripada siswa dengan motivasi belajar rendah, serta terdapat interaksi motivasi belajar dengan media pembelajaran terhadap prestasi belajar IPA-Fisika.   This study aims to determine differences in the use of flash-based IM3 learning media and MS media. Power Point to IPA-Physics learning achievement. Results showed that students who were taught using flash-based media IM3 gives an average performance better than students who were taught using the power point. Students with high motivation to learn the average yield better performance than students with low learning motivation, and there is interaction with the medium of learning motivation toward science learning achievement-Physics.

Ausländische Direktinvestitionen und Technologietransfer im angolanischen Energiesektor

Directory of Open Access Journals (Sweden)

2016-04-01

Full Text Available Dem Zusammenhang von ausländischen Direktinvestionen (Foreign Direct Investment, FDI und Technologietransfer wird sowohl in der Forschung als auch in der politischen Analyse große Bedeutung zugeschrieben. Zahlreiche Veröffentlichungen belegen, dass FDI den Transfer von und/oder den Zugang zu Technologien erleichtert. Allerdings gibt es zu wenige empirische Studien, die diesen Zusammenhang in Bezug auf die Wirtschaft afrikanischer Staaten untersuchen. Der Autor will diese Lücke zu einem kleinen Teil schließen, indem er die Bedeutung des Technologietransfers durch den Zufluss von FDI im Energiesektor Angolas ermittelt. Seine Analyse basiert auf qualitativer Forschung in Angola im Jahr 2014. Er zeigt auf, dass sich die Erzeugung von Energie(trägern und die Verteilungsinfrastruktur - maschinelle Ausrüstung und Qualifizierung - durch den Zufluss von FDI erheblich entwickeln konnte. Allerdings gebe es keinen Beleg dafür, dass dieser Zufluss die endogenen wissenschaftlichen und technologischen Forschungspotenziale im angolanischen Energiesektor gefördert hat. Der Autor empfiehlt politische Maßnahmen zur Förderung dieser Fähigkeiten, insbesondere im Bereich der Produktion.

MALDI TOF imaging mass spectrometry in clinical pathology: a valuable tool for cancer diagnostics (review).

Science.gov (United States)

Kriegsmann, Jörg; Kriegsmann, Mark; Casadonte, Rita

2015-03-01

Matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF) imaging mass spectrometry (IMS) is an evolving technique in cancer diagnostics and combines the advantages of mass spectrometry (proteomics), detection of numerous molecules, and spatial resolution in histological tissue sections and cytological preparations. This method allows the detection of proteins, peptides, lipids, carbohydrates or glycoconjugates and small molecules.Formalin-fixed paraffin-embedded tissue can also be investigated by IMS, thus, this method seems to be an ideal tool for cancer diagnostics and biomarker discovery. It may add information to the identification of tumor margins and tumor heterogeneity. The technique allows tumor typing, especially identification of the tumor of origin in metastatic tissue, as well as grading and may provide prognostic information. IMS is a valuable method for the identification of biomarkers and can complement histology, immunohistology and molecular pathology in various fields of histopathological diagnostics, especially with regard to identification and grading of tumors.

Isospin effects in intermediate energy heavy ion collision

International Nuclear Information System (INIS)

Liu Jianye; Zuo Wei; Yang Yanfang; Zhao Qiang; Guo Wenjun

2001-01-01

Based on the achievements for the intermediate energy heavy ion collision in authors' recent work and the progresses in the world, the isospin effects and the dependence of the entrance channel conditions on them in the intermediate energy heavy ion collisions were introduced, analysed and commended. From the calculation results by using isospin dependence quantum molecular dynamics, it is clear to see that the nuclear stopping power strongly depends on the in-medium isospin dependence nucleon-nucleon cross section and weakly on the symmetry potential in the energy region from about Fermi energy to 150 MeV/u and the intermediate mass fragment multiplicity also sensitively depends on the in-medium isospin dependent nucleon-nucleon cross section and weakly on the symmetry potential in a selected energy region. But the preequilibrium emission neutron-proton ratio is quite contrary, it sensitively depends on the symmetry potential and weakly on the in-medium isospin dependent nucleon-nucleon cross section. In addition to the nuclear stopping sensitively depending on the beam energy, impact parameter and the mass of colliding system and weakly on the neutron-proton ratio of the colliding systems with about the same mass, the preequilibrium emission neutron-neutron ratio sensitively depends on the beam energy and the neutron-proton ratio of colliding system, but weakly on the impact parameter. From above results it is proposed that the nuclear stopping is a new probe to extract the information on the in-medium isospin dependence nucleon-nucleon cross section in energy region from about Fermi energy to 150 MeV/u and the preequilibrium emission neutron-proton ratio is a good probe for extracting the information about the symmetry potential from the lower energy to about 150 MeV/u

Burn out or fade away? On the X-ray and magnetic death of intermediate mass stars

Energy Technology Data Exchange (ETDEWEB)

Drake, Jeremy J.; Kashyap, Vinay; Günther, H. Moritz; Wright, Nicholas J. [Smithsonian Astrophysical Observatory, MS-3, 60 Garden Street, Cambridge, MA 02138 (United States); Braithwaite, Jonathan, E-mail: jdrake@cfa.harvard.edu [Argelander Institut für Astronomie, Auf dem Hügel 71, D-53121 Bonn (Germany)

2014-05-10

The nature of the mechanisms apparently driving X-rays from intermediate mass stars lacking strong convection zones or massive winds remains poorly understood, and the possible role of hidden, lower mass close companions is still unclear. A 20 ks Chandra HRC-I observation of HR 4796A, an 8 Myr old main sequence A0 star devoid of close stellar companions, has been used to search for a signature or remnant of magnetic activity from the Herbig Ae phase. X-rays were not detected and the X-ray luminosity upper limit was L{sub X} ≤ 1.3 × 10{sup 27} erg s{sup –1}. The result is discussed in the context of various scenarios for generating magnetic activity, including rotational shear and subsurface convection. A dynamo driven by natal differential rotation is unlikely to produce observable X rays, chiefly because of the difficulty in getting the dissipated energy up to the surface of the star. A subsurface convection layer produced by the ionization of helium could host a dynamo that should be effective throughout the main sequence but can only produce X-ray luminosities of the order 10{sup 25} erg s{sup –1}. This luminosity lies only moderately below the current detection limit for Vega. Our study supports the idea that X-ray production in Herbig Ae/Be stars is linked largely to the accretion process rather than the properties of the underlying star, and that early A stars generally decline in X-ray luminosity at least 100,000 fold in only a few million years.

REVERBERATION MAPPING OF THE INTERMEDIATE-MASS NUCLEAR BLACK HOLE IN SDSS J114008.71+030711.4

International Nuclear Information System (INIS)

Rafter, Stephen E.; Kaspi, Shai; Behar, Ehud; Kollatschny, Wolfram; Zetzl, Matthias

2011-01-01

We present the results of a reverberation mapping (RM) campaign on the black hole (BH) associated with the active galactic nucleus (AGN) in SDSS J114008.71+030711.4 (hereafter GH08). This object is selected from a sample of 19 candidate intermediate-mass BHs (M BH 6 M sun ) found by Greene and Ho in the Sloan Digital Sky Survey. We used the Hobby-Eberly Telescope to obtain 30 spectra over a period of 178 days in an attempt to resolve the reverberation time lag (τ) between the continuum source and the broad-line region (BLR) in order to determine the radius of the BLR (R BLR ) in GH08. We measure τ to be two days with an upper limit of six days. We estimate the AGN luminosity at 5100 Å to be λL 5100 ≈ 1.1 × 10 43 erg s –1 after deconvolution from the host galaxy. The most well-calibrated R BLR –L relation predicts a time lag that is four times larger than what we measure. Using the measured Hβ full width at half-maximum of 703 ± 110 km s –1 and an upper limit for R BLR =6 light days, we find M BH ∼ 5 M sun as an upper limit to the BH virial mass in GH08, which implies super-Eddington accretion. Based on our measured M BH we propose that GH08 may be another candidate to add to the very short list of AGNs with M BH 6 M sun determined using RM.

Formation rate of water masses in the Japan Sea

International Nuclear Information System (INIS)

Kawamura, Hideyuki; Ito, Toshimichi; Yoon, Jong-Hwan

2007-01-01

Water masses in the subsurface and the intermediate layer are actively formed due to strong winter convection in the Japan Sea. It is probable that some fraction of pollution is carried into the layer below the sea surface together with these water masses, so it is important to estimate the formation rate and turnover time of water masses to study the fate of pollutants. The present study estimates the annual formation rate and the turnover time of water masses using a three-dimensional ocean circulation model and a particle chasing method. The total annual formation rate of water masses below the sea surface amounted to about 3.53±0.55 Sv in the Japan Sea. Regarding representative intermediate water masses, the annual formation rate of the Upper portion of the Japan Sea Proper Water (UJSPW) and the Japan Sea Intermediate Water (JSIW) were estimated to be about 0.38±0.11 and 1.43±0.16 Sv, respectively, although there was little evidence of the formation of deeper water masses below a depth of about 1500 m in a numerical experiment. An estimate of turnover time shows that the UJSPW and the JSIW circulate in the intermediate layer of the Japan Sea with timescales of about 22.1 and 2.2 years, respectively. (author)

ifo Konjunkturprognose 2015/2016: Deutsche Wirtschaft im Aufschwung

OpenAIRE

Wollmershäuser, Timo; Nierhaus, Wolfgang; Berg, Tim Oliver; Breuer, Christian; Garnitz, Johanna; Grimme, Christian; Henzel, Steffen; Hristov, Atanas; Hristov, Nikolay; Meister, Wolfgang; Schröter, Felix; Steiner, Andreas; Wieland, Elisabeth; Wohlrabe, Klaus; Wolf, Anna

2015-01-01

Die deutsche Wirtschaft befindet sich derzeit in einem kräftigen Aufschwung. Das reale Bruttoinlandsprodukt wird in diesem Jahr voraussichtlich um 1,9% expandieren und im kommenden Jahr um 1,8%. Der private Konsum bleibt die Stütze des Aufschwungs, da die Einkommensperspektiven der privaten Haushalte aufgrund der sich weiter verbessernden Arbeitsmarktlage gut sind. Allerdings entfallen allmählich die Kaufkraftgewinne durch den Ölpreisrückgang, so dass sich die Konsumdynamik im Prognosezeitrau...

An intermediate-mass black hole in the darf galaxy Pox 52

Science.gov (United States)

Barth, Aaron

2005-01-01

Do dwarf elliptical and dwarf spiral galaxies contain central black holes with masses below 106 solar masses? Beyond the Local Group dynamical searches for black holes in this mass range are very difficult but the detection of accretion-powered nuclear activity could be used to infer the presence of a black hole. The nearby dwarf spiral galaxy NGC 4395 hosts a faint Seyfert 1 nucleus with a likely black hole mass in the range 104-105 solar masses and for more than a decade it has been the only known example of a Seyfert 1 nucleus in a dwarf galaxy. I will present new Keck spectra of the dwarf galaxy POX 52 which demonstrate that it has a Seyfert 1 spectrum nearly identical to that of NGC 4395. Its velocity dispersion is 37 km/s suggesting a possible black hole mass of order 105 solar masses. I will discuss the prospects for systematic searches for nuclear activity in dwarf galaxies and the implications for black hole demographics.

An Intermediate-Mass Black Hole in the Dwarf Galaxy Pox 52

Science.gov (United States)

Barth, Aaron

Do dwarf elliptical and dwarf spiral galaxies contain central black holes with masses below 106 solar masses? Beyond the Local Group dynamical searches for black holes in this mass range are very difficult but the detection of accretion-powered nuclear activity could be used to infer the presence of a black hole. The nearby dwarf spiral galaxy NGC 4395 hosts a faint Seyfert 1 nucleus with a likely black hole mass in the range 104-105 solar masses and for more than a decade it has been the only known example of a Seyfert 1 nucleus in a dwarf galaxy. I will present new Keck spectra of the dwarf galaxy POX 52 which demonstrate that it has a Seyfert 1 spectrum nearly identical to that of NGC 4395. Its velocity dispersion is 37 km/s suggesting a possible black hole mass of order 105 solar masses. I will discuss the prospects for systematic searches for nuclear activity in dwarf galaxies and the implications for black hole demographics.

Survey of pickup ion signatures in the vicinity of Titan using CAPS/IMS

Science.gov (United States)

Regoli, L. H.; Coates, A. J.; Thomsen, M. F.; Jones, G. H.; Roussos, E.; Waite, J. H.; Krupp, N.; Cox, G.

2016-09-01

Pickup ion detection at Titan is challenging because ion cyclotron waves are rarely detected in the vicinity of the moon. In this work, signatures left by freshly produced pickup heavy ions (m/q ˜ 16 to m/q ˜ 28) as detected in the plasma data by the Cassini Plasma Spectrometer/Ion Mass Spectrometer (CAPS/IMS) instrument on board Cassini are analyzed. In order to discern whether these correspond to ions of exospheric origin, one of the flybys during which the reported signatures were observed is investigated in detail. For this purpose, ion composition data from time-of-flight measurements and test particle simulations to constrain the ions' origin are used. After being validated, the detection method is applied to all the flybys for which the CAPS/IMS instrument gathered valid data, constraining the region around the moon where the signatures are observed. The results reveal an escape region located in the anti-Saturn direction as expected from the nominal corotation electric field direction. These findings provide new constraints for the area of freshly produced pickup ion escape, giving an approximate escape rate of 3.3-2+3×1023 ions· s-1.

Measuring cognitive change with ImPACT: the aggregate baseline approach.

Science.gov (United States)

Bruce, Jared M; Echemendia, Ruben J; Meeuwisse, Willem; Hutchison, Michael G; Aubry, Mark; Comper, Paul

2017-11-01

The Immediate Post-Concussion Assessment and Cognitive Test (ImPACT) is commonly used to assess baseline and post-injury cognition among athletes in North America. Despite this, several studies have questioned the reliability of ImPACT when given at intervals employed in clinical practice. Poor test-retest reliability reduces test sensitivity to cognitive decline, increasing the likelihood that concussed athletes will be returned to play prematurely. We recently showed that the reliability of ImPACT can be increased when using a new composite structure and the aggregate of two baselines to predict subsequent performance. The purpose of the present study was to confirm our previous findings and determine whether the addition of a third baseline would further increase the test-retest reliability of ImPACT. Data from 97 English speaking professional hockey players who had received at least 4 ImPACT baseline evaluations were extracted from a National Hockey League Concussion Program database. Linear regression was used to determine whether each of the first three testing sessions accounted for unique variance in the fourth testing session. Results confirmed that the aggregate baseline approach improves the psychometric properties of ImPACT, with most indices demonstrating adequate or better test-retest reliability for clinical use. The aggregate baseline approach provides a modest clinical benefit when recent baselines are available - and a more substantial benefit when compared to approaches that obtain baseline measures only once during the course of a multi-year playing career. Pending confirmation in diverse samples, neuropsychologists are encouraged to use the aggregate baseline approach to best quantify cognitive change following sports concussion.

Emission of intermediate mass fragments in the heavy ion interaction of (14.0 MeV/u) Pb+Au

International Nuclear Information System (INIS)

Khan, E.U.; Qureshi, I.E.; Shahzad, M.I.; Khattak, F.N.; Khan, H.A.

2001-01-01

We have studied the heavy ion interactions of (14.0 MeV/u) Pb + Au using two threshold detectors, mica and CN-85. A thin layer of Au was deposited on each of the three mica and two CN-85 detector pieces. These target-detector assemblies were exposed to a beam of 14.0 MeV/u Pb ions having the fluence of 1.5x10 6 cm 2 at GSI, Darmstadt, Germany. After removing the target material and etching the samples in appropriate etchants, we scanned 32.29 cm 2 and 24.97 cm 2 area of mica and CN-85, respectively. Based on the observed number of events of various multiplicities, we have determined the total as well as partial experimental reaction cross-sections. It is shown that a significant number of intermediate mass fragments are emitted along with the heavy fragments in the present reaction

ImSET: Impact of Sector Energy Technologies

Energy Technology Data Exchange (ETDEWEB)

Roop, Joseph M.; Scott, Michael J.; Schultz, Robert W.

2005-07-19

This version of the Impact of Sector Energy Technologies (ImSET) model represents the ''next generation'' of the previously developed Visual Basic model (ImBUILD 2.0) that was developed in 2003 to estimate the macroeconomic impacts of energy-efficient technology in buildings. More specifically, a special-purpose version of the 1997 benchmark national Input-Output (I-O) model was designed specifically to estimate the national employment and income effects of the deployment of Office of Energy Efficiency and Renewable Energy (EERE) -developed energy-saving technologies. In comparison with the previous versions of the model, this version allows for more complete and automated analysis of the essential features of energy efficiency investments in buildings, industry, transportation, and the electric power sectors. This version also incorporates improvements in the treatment of operations and maintenance costs, and improves the treatment of financing of investment options. ImSET is also easier to use than extant macroeconomic simulation models and incorporates information developed by each of the EERE offices as part of the requirements of the Government Performance and Results Act.

Solvation of UCl{sub 6}{sup 2-} anionic complex by MeBu{sub 3}N{sup +}, BuMe{sub 2}Im{sup +} and BuMeIm{sup +} cations

Energy Technology Data Exchange (ETDEWEB)

Bosse, Emilie; Den Auwer, Christophe; Berthon, Claude; Guilbaud, Philippe; Moisy, Philippe [CEA Marcoule, DRCP/SCPS, BP 17171, 30207 Bagnols sur Ceze Cedex (France); Grigoriev, Mikhail S. [A.N. Frumkin Institute of Physical Chemistry and Electrochemistry, RAS, Leninskii Prosp. 31, 119991 Moscow (Russian Federation); Nikitenko, Serguei [CNAB, UMR 5084, CNRS - Universite de Bordeaux 1, BP 120 Le Haut Vigneau, 33175 Gradignan Cedex (France); Le Naour, Claire; Cannes, Celine [IPN, UMR 8608, CNRS, Universite Paris-Sud, 91406 Orsay (France)

2008-07-01

The complexes [MeBu{sub 3}N]{sub 2}[UCl{sub 6}] and [BuMe{sub 2}Im]{sub 2}[UCl{sub 6}] were characterized in the solid state and in solution of [MeBu{sub 3}N][Tf{sub 2}N], [BuMe{sub 2}Im][Tf{sub 2}N] and [BuMeIm][Tf{sub 2}N] room temperature ionic liquids using single-crystal XRD, EXAFS, electrochemistry, UV-visible absorption spectroscopy and NMR. In the solid and in solution, the existence of hydrogen bonding between the anionic UCl{sub 6}{sup 2-} complex and the ionic liquid cations were revealed by these techniques. The MeBu{sub 3}N{sup +} cation interacts with UCl{sub 6}{sup 2-} via the protons on the alpha carbon atoms of nitrogen. The protons of the imidazolium ring account for the interaction between the BuMe{sub 2}Im+ cation and the UCl{sub 6}{sup 2-} anion. For the BuMeIm{sup +} cation the major interaction was confirmed between the most acidic proton on C(2) and UCl{sub 6}{sup 2-}. The experimental results also show that the intensity of the interaction between the UCl{sub 6}{sup 2-} anion and the cation varies with the ionic liquid cation in the following order: MeBu{sub 3}N{sup +} {approx} BuMe{sub 2}Im{sup +} << BuMeIm{sup +}. (authors)

Handover Based IMS Registration Scheme for Next Generation Mobile Networks

Directory of Open Access Journals (Sweden)

Shireen Tahira

2017-01-01

Full Text Available Next generation mobile networks aim to provide faster speed and more capacity along with energy efficiency to support video streaming and massive data sharing in social and communication networks. In these networks, user equipment has to register with IP Multimedia Subsystem (IMS which promises quality of service to the mobile users that frequently move across different access networks. After each handover caused due to mobility, IMS provides IPSec Security Association establishment and authentication phases. The main issue is that unnecessary reregistration after every handover results in latency and communication overhead. To tackle these issues, this paper presents a lightweight Fast IMS Mobility (FIM registration scheme that avoids unnecessary conventional registration phases such as security associations, authentication, and authorization. FIM maintains a flag to avoid deregistration and sends a subsequent message to provide necessary parameters to IMS servers after mobility. It also handles the change of IP address for user equipment and transferring the security associations from old to new servers. We have validated the performance of FIM by developing a testbed consisting of IMS servers and user equipment. The experimental results demonstrate the performance supremacy of FIM. It reduces media disruption time, number of messages, and packet loss up to 67%, 100%, and 61%, respectively, as compared to preliminaries.

Regelungen im Verkehr mit Lebensmitteln und Bedarfsgegenständen in Deutschland

Science.gov (United States)

Thomas, Gundula; Freund, Astrid; Gründig, Friedrich

Im Zuge der Globalisierung von Produktion und Handel ändert sich auch der Charakter der Vorschriften im Lebensmittelrecht. Zunehmend treten internationale Rechtsbestimmungen, Abkommen, Standards und andere Normen an die Stelle nationaler Regelungen.

Isoporphyrin Intermediate in Heme Oxygenase Catalysis

Science.gov (United States)

Evans, John P.; Niemevz, Fernando; Buldain, Graciela; de Montellano, Paul Ortiz

2008-01-01

Human heme oxygenase-1 (hHO-1) catalyzes the O2- and NADPH-dependent oxidation of heme to biliverdin, CO, and free iron. The first step involves regiospecific insertion of an oxygen atom at the α-meso carbon by a ferric hydroperoxide and is predicted to proceed via an isoporphyrin π-cation intermediate. Here we report spectroscopic detection of a transient intermediate during oxidation by hHO-1 of α-meso-phenylheme-IX, α-meso-(p-methylphenyl)-mesoheme-III, and α-meso-(p-trifluoromethylphenyl)-mesoheme-III. In agreement with previous experiments (Wang, J., Niemevz, F., Lad, L., Huang, L., Alvarez, D. E., Buldain, G., Poulos, T. L., and Ortiz de Montellano, P. R. (2004) J. Biol. Chem. 279, 42593–42604), only the α-biliverdin isomer is produced with concomitant formation of the corresponding benzoic acid. The transient intermediate observed in the NADPH-P450 reductase-catalyzed reaction accumulated when the reaction was supported by H2O2 and exhibited the absorption maxima at 435 and 930 nm characteristic of an isoporphyrin. Product analysis by reversed phase high performance liquid chromatography and liquid chromatography electrospray ionization mass spectrometry of the product generated with H2O2 identified it as an isoporphyrin that, on quenching, decayed to benzoylbiliverdin. In the presence of H218O2, one labeled oxygen atom was incorporated into these products. The hHO-1-isoporphyrin complexes were found to have half-lives of 1.7 and 2.4 h for the p-trifluoromethyl- and p-methyl-substituted phenylhemes, respectively. The addition of NADPH-P450 reductase to the H2O2-generated hHO-1-isoporphyrin complex produced α-biliverdin, confirming its role as a reaction intermediate. Identification of an isoporphyrin intermediate in the catalytic sequence of hHO-1, the first such intermediate observed in hemoprotein catalysis, completes our understanding of the critical first step of heme oxidation. PMID:18487208

Robust stator resistance identification of an IM drive using model reference adaptive system

International Nuclear Information System (INIS)

Madadi Kojabadi, Hossein; Abarzadeh, Mostafa; Aghaei Farouji, Said

2013-01-01

Highlights: ► We estimate the stator resistance and rotor speed of the IM. ► We proposed a new quantity to estimate the speed and stator resistance of IM. ► The proposed algorithm is robust to rotor resistance variations. ► We estimate the IM speed and stator resistance simultaneously to avoid speed error. - Abstract: Model reference adaptive system (MRAS) based robust stator resistance estimator for sensorless induction motor (IM) drive is proposed. The MRAS is formed with a semi-active power quantity. The proposed identification method can be achieved with on-line tuning of the stator resistance with robustness against rotor resistance variations. Stable and efficient estimation of IM speed at low region will be guaranteed by simultaneous identification of IM speed and stator resistance. The stability of proposed stator resistance estimator is checked through Popov’s hyperstability theorem. Simulation and experimental results are given to highlight the feasibility, the simplicity, and the robustness of the proposed method.

Thermal Degradation Study of IM7/DMBZ-15 High Temperature Composite by TGA/FTIR

National Research Council Canada - National Science Library

Nadler, Melvin

2003-01-01

(U) High temperature graphite composites such as IM7/8552 epoxy, IM7/5250 BMI, and IM7/DMBZ-15 polyimide show blistering and/or "catastrophic" delamination when rapidly heated to temperatures above...

Chiral analysis of bambuterol, its intermediate and active drug in human plasma by liquid chromatography-tandem mass spectrometry: Application to a pharmacokinetic study.

Science.gov (United States)

Zhou, Ting; Liu, Shan; Zhao, Ting; Zeng, Jing; He, Mingzhi; Xu, Beining; Qu, Shanshan; Xu, Ling; Tan, Wen

2015-08-01

A sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method has been developed for simultaneous chiral analysis of an antiasthma drug bambuterol, its key intermediate monocarbamate bambuterol and its active drug terbutaline in human plasma. All samples were extracted with ethyl acetate and separated on an Astec Chirobiotic T column under isocratic elution with a mobile phase consisting of methanol and water with the addition of 20mm ammonium acetate and 0.005% (v/v) formic acid at 0.6mL/min. The analytes were detected by a Xevo TQ-S tandem mass spectrometer with positive electrospray ionization in multiple reaction monitoring mode. The established method has high sensitivity with the lower limit of quantifications of 25.00pg/mL for bambuterol enantiomers, and 50.00pg/mL for monocarbamate bambuterol and terbutaline enantiomers, respectively. The calibration curves for bambuterol enantiomers were linear in the range of 25.00-2500pg/mL, and for monocarbamate bambuterol and terbutaline enantiomers were linear in the range of 50.00-5000pg/mL. The intra- and inter-day precisions were <12.4%. All the analytes were separated in 18.0min. For the first time, the validated method was successfully applied to an enantioselective pharmacokinetic study of rac-bambuterol in 8 healthy volunteers. According to the results, this chiral LC-MS/MS assay provides a suitable and robust method for the enantioselectivity and interaction study of the prodrug bambuterol, the key intermediate monocarbamate bambuterol and its active drug terbutaline in human. Copyright © 2015 Elsevier B.V. All rights reserved.

Traveling-wave ion mobility mass spectrometry of protein complexes

DEFF Research Database (Denmark)

Salbo, Rune; Bush, Matthew F; Naver, Helle

2012-01-01

The collision cross-section (Ω) of a protein or protein complex ion can be measured using traveling-wave (T-wave) ion mobility (IM) mass spectrometry (MS) via calibration with compounds of known Ω. The T-wave Ω-values depend strongly on instrument parameters and calibrant selection. Optimization ...

[Variation im heutigen Deutsch...] / Laura Tidrike

Index Scriptorium Estoniae

Tidrike, Laura

2008-01-01

Arvustus: Variation im heutigen Deutsch : Perspektiven für den Sprachunterricht / hrsg. v. Eva Neuland. Frankfurt am Main : Lang, 2006. (Sprache - Kommunikation - Kultur. Soziolinguistische Beiträge ; Vol. 4)

Global R&D through the Intelligent Manufacturing Systems (IMS) program

Science.gov (United States)

Huray, Paul G.

1997-01-01

The industry-led, international intelligent manufacturing systems (IMS) program provides a special vehicle for joint research and development between government, industry and academia in the United States, Canada, Japan, Australia, and Europe. Since its beginning in 1989, the IMS program has progressed through a feasibility phase which demonstrated that international legal barriers, trade issues, and intellectual property problems could be overcome. The program is constructed to provide higher quality design, customized products, shorter delivery cycles and lower costs. Interactions between partner companies have led to new business opportunities for mutual profit and some claim to have learned strategic information about their international competitors. The IMS program is growing through the participation of hundreds of corporate and university partners who share responsibilities in specific projects and jointly reap benefits for their manufacturing products and processes. The logic for choosing or not choosing the IMS mechanisms will be discussed and R and D projects will be identified.

Estudios por imágenes en reumatismo

Directory of Open Access Journals (Sweden)

Muñoz Ch. Sara, Dra.

2012-07-01

Los grandes avances tecnológicos de la última década han mejorado la calidad y cantidad de información que las distintas técnicas aportan, especialmente la RM; esto hace vislumbrar un cambio significativo en el diagnóstico por imágenes, ya que en el futuro no solo estará basado en los cambios morfológicos en órganos y tejidos; las imágenes obtenidas aportarán información bioquímica, molecular y fisiológica de los procesos patológicos facilitando su diagnóstico aun más precoz.

Using IMS VDEX in Agrega

Directory of Open Access Journals (Sweden)

Jose Manuel Canabal

2009-03-01

Full Text Available An essential element in a learning object repository is the meta-information associated with the resources housed by the repository, as this is what enables the objects to be retrieved. In many cases, the meta-information which is described consists of the classification of a resource in relation to a taxonomy or thesaurus. Agrega is a network of learning object repositories in which an LOM profile, called LOM-ES, has been used to label the objects. Part of the meta-information described corresponds to the classification of the object with respect to a group of taxonomies and a thesaurus, which have had to be described using the ims vdex standard to enable them to be managed from the federation nodes. This article describes the way in which ims vdex has been used in order to create this description and how these metadata instances are managed.

Effects of drift gas on collision cross sections of a protein standard in linear drift tube and traveling wave ion mobility mass spectrometry.

Science.gov (United States)

Jurneczko, Ewa; Kalapothakis, Jason; Campuzano, Iain D G; Morris, Michael; Barran, Perdita E

2012-10-16

There has been a significant increase in the use of ion mobility mass spectrometry (IM-MS) to investigate conformations of proteins and protein complexes following electrospray ionization. Investigations which employ traveling wave ion mobility mass spectrometry (TW IM-MS) instrumentation rely on the use of calibrants to convert the arrival times of ions to collision cross sections (CCS) providing "hard numbers" of use to structural biology. It is common to use nitrogen as the buffer gas in TW IM-MS instruments and to calibrate by extrapolating from CCS measured in helium via drift tube (DT) IM-MS. In this work, both DT and TW IM-MS instruments are used to investigate the effects of different drift gases (helium, neon, nitrogen, and argon) on the transport of multiply charged ions of the protein myoglobin, frequently used as a standard in TW IM-MS studies. Irrespective of the drift gas used, recorded mass spectra are found to be highly similar. In contrast, the recorded arrival time distributions and the derived CCS differ greatly. At low charge states (7 ≤ z ≤ 11) where the protein is compact, the CCS scale with the polarizability of the gas; this is also the case for higher charge states (12 ≤ z ≤ 22) where the protein is more unfolded for the heavy gases (neon, argon, and nitrogen) but not the case for helium. This is here interpreted as a different conformational landscape being sampled by the lighter gas and potentially attributable to increased field heating by helium. Under nanoelectrospray ionization (nESI) conditions, where myoglobin is sprayed from an aqueous solution buffered to pH 6.8 with 20 mM ammonium acetate, in the DT IM-MS instrument, each buffer gas can yield a different arrival time distribution (ATD) for any given charge state.

Detection of high molecular weight proteins by MALDI imaging mass spectrometry.

Science.gov (United States)

Mainini, Veronica; Bovo, Giorgio; Chinello, Clizia; Gianazza, Erica; Grasso, Marco; Cattoretti, Giorgio; Magni, Fulvio

2013-06-01

MALDI imaging mass spectrometry (IMS) is a unique technology to explore the spatial distribution of biomolecules directly on tissues. It allows the in situ investigation of a large number of small proteins and peptides. Detection of high molecular weight proteins through MALDI IMS still represents an important challenge, as it would allow the direct investigation of the distribution of more proteins involved in biological processes, such as cytokines, enzymes, neuropeptide precursors and receptors. In this work we compare the traditional method performed with sinapinic acid with a comparable protocol using ferulic acid as the matrix. Data show a remarkable increase of signal acquisition in the mass range of 20k to 150k Th. Moreover, we report molecular images of biomolecules above 70k Th, demonstrating the possibility of expanding the application of this technology both in clinical investigations and basic science.

Experimental study on the performance of the vapor injection refrigeration system with an economizer for intermediate pressures

Science.gov (United States)

Moon, Chang-Uk; Choi, Kwang-Hwan; Yoon, Jung-In; Kim, Young-Bok; Son, Chang-Hyo; Ha, Soo-Jung; Jeon, Min-Ju; An, Sang-Young; Lee, Joon-Hyuk

2018-04-01

In this study, to investigate the performance characteristics of vapor injection refrigeration system with an economizer at an intermediate pressure, the vapor injection refrigeration system was analyzed under various experiment conditions. As a result, the optimum design data of the vapor injection refrigeration system with an economizer were obtained. The findings from this study can be summarized as follows. The mass flow rate through the compressor increases with intermediate pressure. The compression power input showed an increasing trend under all the test conditions. The evaporation capacity increased and then decreased at the intermediate pressure, and as such, it became maximum at the given intermediate pressure. The increased mass flow rate of the by-passed refrigerant enhanced the evaporation capacity at the low medium pressure range, but the increased saturation temperature limited the subcooling degree of the liquid refrigerant after the application of the economizer when the intermediate pressure kept rising, and degenerated the evaporation capacity. The coefficient of performance (COP) increased and then decreased with respect to the intermediate pressures under all the experiment conditions. Nevertheless, there was an optimum intermediate pressure for the maximum COP under each experiment condition. Therefore, the optimum intermediate pressure in this study was found at -99.08 kPa, which is the theoretical standard medium pressure under all the test conditions.

New probe of dark-matter properties: gravitational waves from an intermediate-mass black hole embedded in a dark-matter minispike.

Science.gov (United States)

Eda, Kazunari; Itoh, Yousuke; Kuroyanagi, Sachiko; Silk, Joseph

2013-05-31

An intermediate-mass black hole (IMBH) may have a dark-matter (DM) minihalo around it and develop a spiky structure within less than a parsec from the IMBH. When a stellar mass object is captured by the minihalo, it eventually infalls into such an IMBH due to gravitational wave backreaction which in turn could be observed directly by future space-borne gravitational wave experiments such as eLISA and NGO. In this Letter, we show that the gravitational wave (GW) detectability strongly depends on the radial profile of the DM distribution. So if the GW is detected, the power index, that is, the DM density distribution, would be determined very accurately. The DM density distribution obtained would make it clear how the IMBH has evolved from a seed black hole and whether the IMBH has experienced major mergers in the past. Unlike the γ-ray observations of DM annihilation, GW is just sensitive to the radial profile of the DM distribution and even to noninteracting DM. Hence, the effect we demonstrate here can be used as a new and powerful probe into DM properties.

Cryo-EM structures of two bovine adenovirus type 3 intermediates

International Nuclear Information System (INIS)

Cheng, Lingpeng; Huang, Xiaoxing; Li, Xiaomin; Xiong, Wei; Sun, Wei; Yang, Chongwen; Zhang, Kai; Wang, Ying; Liu, Hongrong; Huang, Xiaojun; Ji, Gang; Sun, Fei; Zheng, Congyi; Zhu, Ping

2014-01-01

Adenoviruses (Ads) infect hosts from all vertebrate species and have been investigated as vaccine vectors. We report here near-atomic structures of two bovine Ad type 3 (BAd3) intermediates obtained by cryo-electron microscopy. A comparison between the two intermediate structures reveals that the differences are localized in the fivefold vertex region, while their facet structures are identical. The overall facet structure of BAd3 exhibits a similar structure to human Ads; however, BAd3 protein IX has a unique conformation. Mass spectrometry and cryo-electron tomography analyses indicate that one intermediate structure represents the stage during DNA encapsidation, whilst the other intermediate structure represents a later stage. These results also suggest that cleavage of precursor protein VI occurs during, rather than after, the DNA encapsidation process. Overall, our results provide insights into the mechanism of Ad assembly, and allow the first structural comparison between human and nonhuman Ads at backbone level. - Highlights: • First structure of bovine adenovirus type 3. • Some channels are located at the vertex of intermediate during DNA encapsidation. • Protein IX exhibits a unique conformation of trimeric coiled–coiled structure. • Cleavage of precursor protein VI occurs during the DNA encapsidation process

Cryo-EM structures of two bovine adenovirus type 3 intermediates

Energy Technology Data Exchange (ETDEWEB)

Cheng, Lingpeng; Huang, Xiaoxing; Li, Xiaomin [National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101 (China); Xiong, Wei [State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Luo-jia-shan, Wuhan, Hubei 430072 (China); Sun, Wei; Yang, Chongwen; Zhang, Kai; Wang, Ying [National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101 (China); Liu, Hongrong [College of Physics and Information Science, Hunan Normal University, Changsha, Hunan 410081 (China); Huang, Xiaojun; Ji, Gang; Sun, Fei [National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101 (China); Zheng, Congyi, E-mail: cctcc202@whu.edu.cn [State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Luo-jia-shan, Wuhan, Hubei 430072 (China); Zhu, Ping, E-mail: zhup@ibp.ac.cn [National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101 (China)

2014-02-15

Adenoviruses (Ads) infect hosts from all vertebrate species and have been investigated as vaccine vectors. We report here near-atomic structures of two bovine Ad type 3 (BAd3) intermediates obtained by cryo-electron microscopy. A comparison between the two intermediate structures reveals that the differences are localized in the fivefold vertex region, while their facet structures are identical. The overall facet structure of BAd3 exhibits a similar structure to human Ads; however, BAd3 protein IX has a unique conformation. Mass spectrometry and cryo-electron tomography analyses indicate that one intermediate structure represents the stage during DNA encapsidation, whilst the other intermediate structure represents a later stage. These results also suggest that cleavage of precursor protein VI occurs during, rather than after, the DNA encapsidation process. Overall, our results provide insights into the mechanism of Ad assembly, and allow the first structural comparison between human and nonhuman Ads at backbone level. - Highlights: • First structure of bovine adenovirus type 3. • Some channels are located at the vertex of intermediate during DNA encapsidation. • Protein IX exhibits a unique conformation of trimeric coiled–coiled structure. • Cleavage of precursor protein VI occurs during the DNA encapsidation process.

Clinical impact of body mass index on prostate biopsy in patients with intermediate PSA levels

International Nuclear Information System (INIS)

Sekita, Nobuyuki; Chin, Kensei; Fujimura, Masaaki; Mikami, Kazuo; Suzuki, Hiroyoshi; Kamijima, Shuichi

2008-01-01

From April 2005 to September 2007, 480 patients underwent transrectal prostate biopsy at our institution. The clinical data including age, serum prostate specific antigen (PSA) level, prostate volume and body mass index (BMI) were obtained, and the cancer detection rates and pathological findings were evaluated in 305 cases with a PSA concentration of 4.0 to 10.0 ng/ml. Prostate volume was calculated from magnetic resonance imaging (MRI) findings. The 305 patients were categorized according to their BMI into three groups (normal, less than 22 kg/m 2 ; overweight, 22-25 kg/m 2 ; and obese, more than 25 kg/m 2 ). Cancer detection rates and histopathologic findings were compared between the groups. Multivariate logistic regression analysis was also performed. Prostate cancer was detected in 127 patients. No significant differences in BMI were observed between biopsy-positive and biopsy-negative cases (p=0.965), and the detection rates of prostate cancer observed in the three groups were not significantly different. There was a significant association between BMI and the findings of high Gleason score (more than 4+3) (p=0.048). BMI was not a contributory factor of prostate cancer detection for cases with intermediate PSA levels; however, patients with high BMI may have high-grade malignancy features. (author)

İletişim Çalışmalarında Yeni Bir Mecra: Finansal İletişim

Directory of Open Access Journals (Sweden)

Gökhan Gökgöz

2013-09-01

Full Text Available 1970’li yıllar toplumsal ve politik tarih açısından önemli bir uğrağı temsil eder. Bu yılların başında yaşanan kriz, ekonominin işleyiş süreçlerini, devletin yapısını ve toplumsal alanın tasavvur edilme biçimini büyük ölçüde değiştirmiştir. Bu dönemde, finansal sermaye, kapitalizm içerisinde bir hegemonik lider olarak ön plana çıkmış; devlet, bir yandan üretimin çekirdeğinden uzak bir yerde konumlandırılırken diğer yandan paranın dolaşım kanallarının rehabilitasyonu işine odaklanmış; insana ilişkin değerler, kültürel mefhumlar ve toplumsal pratikler ise birer değişken olarak ekonomi-politikanın merkezine taşınmıştır. Kültür ile ekonomi arasındaki geleneksel ilişki bozulmuş; bir ekonomi-politikanın başarısı, toplumsal aktörlere temas etme kabiliyeti ile paralel hale gelmiştir. Finansallaşma sürecinde bu temas, iletişim politikaları vasıtasıyla sağlanır; ekonomi-politika ve bundan sorumlu merkezi kurumlarla toplumsal alan arasındaki bağ, iletişim stratejileri üzerinden kurulur; ekonomik alan ile kültürel alan arasındaki boşluk, iletişim kanalları içerisinden taşınan enformasyon marifetiyle doldurulur; insana ilişkin öngörülemezlikler, iletişim süreçleri vasıtasıyla öngörülebilir kılınır. Bu çalışmada, iletişim çalışmaları içerisinde yeni bir mecra olarak çağrılan “finansal iletişim”in farklı temas noktalarına işaret edilecek ve her bir uğrağın finansal iletişim alanına bağlandığı nokta, modeller üzerinden gösterilecektir. 

Ein Ausblick auf Supply-Chain-Management im Jahr 2016

DEFF Research Database (Denmark)

Wieland, Andreas

2016-01-01

Wie sieht Supply-Chain-Management im Jahr 2016 aus? Was erwartet uns? Vieles deutet darauf hin, dass SCM in Zukunft sogar noch mehr auf den Kunden gerichtet sein könnte als bisher.......Wie sieht Supply-Chain-Management im Jahr 2016 aus? Was erwartet uns? Vieles deutet darauf hin, dass SCM in Zukunft sogar noch mehr auf den Kunden gerichtet sein könnte als bisher....

Intermediate vector-boson properties at the CERN super proton synchrotron collider

International Nuclear Information System (INIS)

Arnison, A; Albrow, M.G.; Allkofer, O.C.; Astbury, A.; Aubert, B.; Bacci, C.; Batley, J.R.; Bauer, G.; Bettini, A.; Bezaguet, A.; Bock, R.K.; Brena, C.; Buckley, E.; Bunn, J.; Busetto, G.; Catz, P.; Cennini, P.; Centro, S.; Ceradini, F.; Ciapetti, G.; Ciottolin, S.; Cline, D.; Cochet, C.; Colas, J.; Colas, P.; Corden, M.; Cox, G.; Dallman, D.; Dau, D.; DeBeer, M.; De Giorgi, M.; Della Negra, M.; Demoulin, M.; Denby, E.; Denegri, D.; Di Ciaccio, A.; Dobrzynski, L.; Dorenbosch, J.; Dowell, J.D.; Duchovni, E.; Edgecock, R.; Eggert, K.; Eisenhandler, E.; Ellis, N.; Erhard, P.; Faissner, H.; Fincke Keeler, M.; Flynn, P.; Fontaine, G.; Frey, R.; Fruehwirth, R.; Garvey, J.; Geer, S.; Ghesquiere, C.; Ghez, P.; Ghio, F.; Gibson, W.R.; Giradu-Heraud, Y.; Givernaud, A.; Gonidec, A.; Goodman, M.; Grassmann, H.; Grayer, G.; Guryn, W.; Haynes, W.; Hoffmann, H.; Holthuizen, D.J.; Homer, R.J.; Honma, A.; Jank, W.; Jorat, G.; Kalmus, P.I.P.; Karimaeki, V.; Keeler, R.; Kenyon, I.; Kernan, A.; Kinnunen, R.; Kroll, J.; Kryn, D.; Kyberd, P.; Lacava, F.; Laugier, J.P.; Lees, J.P.; Leuchs, R.; Levegrun, S.; Leveque, A.; Levi, M.; Linglin, D.; Locci, E.; Markiewicz, T.; Markytan, M.; Martin, T.; Maurin, G.; McMahon, T.; Mendiburu, J.P.; Meneguzzo, A.; Meyer, O.; Meyer, T.; Minard, M.N.; Mohammadi, M.; Morgan, K.; Moricca, M.; Moser, H.; Mours, B.; Muller, T.; Nandi, A.; Naumann, L.; Norton, A.; Paoluzi, L.; Pascoli, D.; Pauss, F.; Perault, C.; Piano Mortari, G.; Pietarinen, E.; Pimiae, M.; Pitman, D.; Placci, A.; Porte, J.P.; Radermacher, E.; Raja, R.; Ransdell, J.; Redelberger, T.; Reithler, H.; Revol, J.P.; Rijssenbeek, M.; Rohlf, J.; Rossi, P.; Roberts, C.; Rubbia, C.; Sajot, G.; Salvini, G.; Sass, J.; Sadoulet, B.; Savoy-Navarro, A.; Schinzel, D.; Schwartz, A.; Scott, W.; Shah, T.P.; Sheer, I.; Siotis, I.; Smith, D.; Sobie, R.; Stenzler, M.; Strauss, J.; Streets, J.; Stubenrauch, C.; Summers, D.; Sumorok, K.; Szoncso, F.; Tao, C.; Thompson, G.; Tscheslog, E.; Tuominiemi, J.; Eijk, B. van; Verecchia, P.; Vialle, J.P.; Virdee, T.S.; Schmitt, H. von der; Von Schlippe, W.; Vrana, J.; Vuillemin, V.; Wahl, H.D.; Watkins, P.; Wilke, R.; Wilson, J.; Wingerter, I.; Wimpenny, S.J.; Wulz, C.E.; Wyatt, T.; Yvert, M.; Zaganidis, N.; Zanello, L.; Zotto, P.

1986-01-01

The properties of a sample of 172 charged intermediate vector bosons decaying in the (eνsub(e)) channel and 16 neutral intermediate vector bosons decaying in the (e + e - ) channel are described. Masses, decay widths, decay angular distributions, and production cross-sections are given; they shown are to be in excellent agreement with the expectations of the SU 2 x U 1 standard model. A limit is put on the number of light-neutrino types Nsub(ν) <= 10 at 90% c.l. (orig.)

Report on converging insert moulding with µ-IM

DEFF Research Database (Denmark)

Islam, Aminul

moulding with µ-IM  Task 5.2.1 and COTECH demonstrator: guide line for 5PRC production based on the concept of Task 5.2.1 Information and results provided by this deliverable will be directly used for one of the COTECH demonstrators production which will call for convergent insert moulding with µ......Task 5.2.1 deals with the technical feasibility of converging the state-of-the-art µ IM process with insert moulding to offer a wide range of multi-material µ components. The main objective of this deliverable is to summarize state-of-the-art information and to make the guideline needed...... for the convergence. In particular the following aspects are summed up in the deliverable:  Need for converging insert moulding with µ-IM  Objectives and expected outcome from task 5.2.1  State-of-the-art micro insert moulding and different scenario of micro insert moulding  Challenges ahead of converging insert...

A SURVEY ON INDIAN EXPERIENCE ON INTEGRATED MANAGEMENT STANDARDS (IMS

Directory of Open Access Journals (Sweden)

H. Khanna

2009-09-01

Full Text Available Adoption of management systems standards is a key issue in manufacturing industry in India. Following the global trend quality and environmental issues are gaining importance. However the number of ISO 14001 certified companies are much less in India as compared to ISO 9001. The integration of ISO 14001 with ISO 9001 may help companies to sustain competitive advantage and overcome disappointments with quality standards and in turn encourage companies to adopt good environmental practices. The aim of this research is to study the implementation of integrated management standards (IMS by the manufacturing organizations in India. The different aspects of integration and benefits of IMS implementation are analyzed. This r esearch is based on empirical study carried out in Indian manufacturing firms, involving the application of a questionnaire. This questionnaire was tested on 50 manufacturing companies in India. The study reveals that focus on stakeholders; top management commitment and training are critical success factors for implementation of IMS. The main benefits of integration are discussed. The small sample size is one of the major limitations of this study. The paper informs the managers in manufacturing organizations and practitioners of management system standards especially in developing countries about IMS and will enable them to adopt IMS in future so that those organizations may not implement multiple and overlapping MSS(Management System Standards.

Environmental trace analysis by means of supersensitive GC-IMS

International Nuclear Information System (INIS)

Leonhardt, J.W.

1997-01-01

The effective control of pollutants in ambient air requires their fast in situ identification and concentration determination of chemical compounds in the range of micrograms per m 3 . There are attempts to use conventional analytical techniques as portable GC and GC-MS. These systems are relatively expensive. A new supersensitive ion Mobility Sensor (IMS) was developed and checked by IUT Ltd, which meets the new demands. The use of tritium sources is an advantage in comparison with other IMS being equipped by nickel-63, the application of which is rather critical in respect of the radiation protection. On the other hand an integrated separation column allows to reduce interferences by matrix effects. The technical parameters of the IUT GC- IMS and some of its most important applications are briefly presented

Jetted tidal disruptions of stars as a flag of intermediate mass black holes at high redshifts

Science.gov (United States)

Fialkov, Anastasia; Loeb, Abraham

2017-11-01

Tidal disruption events (TDEs) of stars by single or binary supermassive black holes (SMBHs) brighten galactic nuclei and reveal a population of otherwise dormant black holes. Adopting event rates from the literature, we aim to establish general trends in the redshift evolution of the TDE number counts and their observable signals. We pay particular attention to (I) jetted TDEs whose luminosity is boosted by relativistic beaming and (II) TDEs around binary black holes. We show that the brightest (jetted) TDEs are expected to be produced by massive black hole binaries if the occupancy of intermediate mass black holes (IMBHs) in low-mass galaxies is high. The same binary population will also provide gravitational wave sources for the evolved Laser Interferometer Space Antenna. In addition, we find that the shape of the X-ray luminosity function of TDEs strongly depends on the occupancy of IMBHs and could be used to constrain scenarios of SMBH formation. Finally, we make predictions for the expected number of TDEs observed by future X-ray telescopes finding that a 50 times more sensitive instrument than the Burst Alert Telescope (BAT) on board the Swift satellite is expected to trigger ˜10 times more events than BAT, while 6-20 TDEs are expected in each deep field observed by a telescope 50 times more sensitive than the Chandra X-ray Observatory if the occupation fraction of IMBHs is high. Because of their long decay times, high-redshift TDEs can be mistaken for fixed point sources in deep field surveys and targeted observations of the same deep field with year-long intervals could reveal TDEs.

Magnetized Converging Flows toward the Hot Core in the Intermediate/High-mass Star-forming Region NGC 6334 V

International Nuclear Information System (INIS)

Juárez, Carmen; Girart, Josep M.; Zamora-Avilés, Manuel; Palau, Aina; Ballesteros-Paredes, Javier; Tang, Ya-Wen; Koch, Patrick M.; Liu, Hauyu Baobab; Zhang, Qizhou; Qiu, Keping

2017-01-01

We present Submillimeter Array (SMA) observations at 345 GHz toward the intermediate/high-mass cluster-forming region NGC 6334 V. From the dust emission we spatially resolve three dense condensations, the brightest one presenting the typical chemistry of a hot core. The magnetic field (derived from the dust polarized emission) shows a bimodal converging pattern toward the hot core. The molecular emission traces two filamentary structures at two different velocities, separated by 2 km s −1 , converging to the hot core and following the magnetic field distribution. We compare the velocity field and the magnetic field derived from the SMA observations with magnetohydrodynamic simulations of star-forming regions dominated by gravity. This comparison allows us to show how the gas falls in from the larger-scale extended dense core (∼0.1 pc) of NGC 6334 V toward the higher-density hot core region (∼0.02 pc) through two distinctive converging flows dragging the magnetic field, whose strength seems to have been overcome by gravity.

L1188: A Promising Candidate for Cloud–Cloud Collisions Triggering the Formation of Low- and Intermediate-mass Stars

Energy Technology Data Exchange (ETDEWEB)

Gong, Yan; Fang, Min; Mao, Ruiqing; Zhang, Shaobo; Wang, Yuan; Su, Yang; Chen, Xuepeng; Yang, Ji; Wang, Hongchi; Lu, Dengrong, E-mail: ygong@pmo.ac.cn [Purple Mountain Observatory and Key Laboratory of Radio Astronomy, Chinese Academy of Sciences, 2 West Beijing Road, 210008 Nanjing (China)

2017-01-20

We present a new large-scale (2° × 2°) simultaneous {sup 12}CO, {sup 13}CO, and C{sup 18}O (J = 1–0) mapping of L1188 with the Purple Mountain Observatory 13.7 m telescope. Our observations have revealed that L1188 consists of two nearly orthogonal filamentary molecular clouds at two clearly separated velocities. Toward the intersection showing large velocity spreads, we find several bridging features connecting the two clouds in velocity, and an open arc structure that exhibits high excitation temperatures, enhanced {sup 12}CO and {sup 13}CO emission, and broad {sup 12}CO line wings. This agrees with the scenario that the two clouds are colliding with each other. The distribution of young stellar object (YSO) candidates implies an enhancement of star formation in the intersection of the two clouds. We suggest that a cloud–cloud collision happened in L1188 about 1 Myr ago, possibly triggering the formation of low- and intermediate-mass YSOs in the intersection.

Multiplicity correlations of intermediate-mass fragments with pions and fast protons in 12C + 197AU

International Nuclear Information System (INIS)

Turzo, K.; Begemann-Blaich, M.L.; Auger, G.

2003-12-01

Low-energy π + (E π 12 C+ 197 Au collisions at incident energies from 300 to 1800 MeV per nucleon were detected with the Si-Si(Li)-CsI(Tl) calibration telescopes of the INDRA multidetector. The inclusive angular distributions are approximately isotropic, consistent with multiple rescattering in the target spectator. The multiplicity correlations of the low-energy pions and of energetic protons (E p >or ≤ 150 MeV) with intermediate-mass fragments were determined from the measured coincidence data. The deduced correlation functions 1 + R ∼ 1.3 for inclusive event samples reflect the strong correlations evident from the common impact-parameter dependence of the considered multiplicities. For narrow impact-parameter bins (based on charged-particle multiplicity), the correlation functions are close to unity and do not indicate strong additional correlations. Only for pions at high particle multiplicities (central collisions) a weak anticorrelation is observed, probably due to a limited competition between these emissions. Overall, the results are consistent with the equilibrium assumption made in statistical multifragmentation scenarios. Predictions obtained with intranuclear cascade models coupled to the statistical multifragmentation model are in good agreement with the experimental data. (orig.)

Digital Medien im Naturwissenschaftlichen Unterricht

CERN Document Server

Meßinger-Koppelt, Jenny

2014-01-01

„Morgens, 8 Uhr: Kurz vor der Schultür werden noch die neuesten Posts auf Facebook geliked, ein Selfie in die Whats-App-Gruppe hochgeladen oder auf YouTube noch ein #LOL-Video gestreamed. Dann klingelt es und die Digital Natives greifen wieder zu Stift, Papier und werden frontal mit Fakten gefüttert“ (A. Spang). Für Schüler sind Internet, Smartphone und Tablet-PC heute selbstverständlicher Teil ihrer Lernwelt. Und auch die Alltags- und Berufswelt ist ohne Informationstechnologien nicht mehr vorstellbar. Doch was bedeutet das für den Schulunterricht, insbesondere für die techniknahen Naturwissenschaften? Wie gelingt im Schulalltag die Balance zwischen Kreidezeit und interaktivem Whiteboard nach mittlerweile 30 Jahren Erfahrung mit Schulcomputern? Der vorliegende Sammelband präsentiert zahlreiche Praxisbeispiele aus dem Schulalltag zum sinnvollen Einsatz digitaler Medien im Biologie-, Chemie- und Physik-Unterricht sowie den aktuellen Stand der fachdidaktischen Forschung. Zu Wort kommen Hochschullehr...

Mass distributions in nucleon-induced fission at intermediate energies

CERN Document Server

Duijvestijn, M C; Hambsch, F J

2001-01-01

Temperature-dependent fission barriers and fission-fragment mass distributions are calculated in the framework of the multimodal random neck-rupture model (MM-RNRM). It is shown how the distinction between the different fission modes disappears at higher excitation energies, due to the melting of shell effects. The fission-fragment mass yield calculations are coupled to the nuclear reaction code ALICE-91, which takes into account the competition between the other reaction channels and fission. With the combination of the temperature-dependent MM-RNRM and ALICE-91 nucleon-induced fission is investigated at energies between 10 and 200 MeV for nuclei varying from Au to Am. (72 refs).

CORPORATIVE MOTIVES ON IMPLEMENTATION OF INTEGRATED MANAGEMENT SYSTEM (IMS

Directory of Open Access Journals (Sweden)

Dragan Rajkovic

2009-09-01

Full Text Available Integration of management systems for quality, environment, health and risk management as well as corporative social responsibilities is workable corporative approach to reduce costs, effective use of resources, higher motivation of employees and better fulfillment of requirements of social engagements and stakeholders. This paper presents contents of literature and review of a company motives on integrated management system (IMS implementation, namely factors affecting the IMS implementation.

Intermediate L-K molecular-orbital radiation from heavy ion collisions

International Nuclear Information System (INIS)

Heinig, K.H.; Jaeger, H.U.; Richter, H.; Woittennek, H.

1976-01-01

The structure of X-ray continua observed recently in violent collisions between mean-mass atoms can be explained by a superposition of K molecular orbital (KMO) radiation and an intermediate L-K molecular orbital (ILKMO) radiation of high intensity which is due to 2psigma vacancies. (Auth.)

Visualisation of abscisic acid and 12-oxo-phytodienoic acid in immature Phaseolus vulgaris L. seeds using desorption electrospray ionisation-imaging mass spectrometry

Science.gov (United States)

Enomoto, Hirofumi; Sensu, Takuya; Sato, Kei; Sato, Futoshi; Paxton, Thanai; Yumoto, Emi; Miyamoto, Koji; Asahina, Masashi; Yokota, Takao; Yamane, Hisakazu

2017-02-01

The plant hormone abscisic acid (ABA) and the jasmonic acid related-compound 12-oxo-phytodienoic acid (OPDA) play crucial roles in seed development, dormancy, and germination. However, a lack of suitable techniques for visualising plant hormones has restricted the investigation of their biological mechanisms. In the present study, desorption electrospray ionisation-imaging mass spectrometry (DESI-IMS), a powerful tool for visualising metabolites in biological tissues, was used to visualise ABA and OPDA in immature Phaseolus vulgaris L. seed sections. The mass spectra, peak values and chemical formulae obtained from the analysis of seed sections were consistent with those determined for ABA and OPDA standards, as were the precursor and major fragment ions observed in tandem mass spectrometry (MS/MS) imaging. Furthermore, the precursor and fragment ion images showed similar distribution patterns. In addition, the localisation of ABA and OPDA using DESI-IMS was confirmed using liquid chromatography-MS/MS (LC-MS/MS). The results indicated that ABA was mainly distributed in the radical and cotyledon of the embryo, whereas OPDA was distributed exclusively in external structures, such as the hilum and seed coat. The present study is the first to report the visualisation of plant hormones using IMS, and demonstrates that DESI-IMS is a promising technique for future plant hormone research.

Detection of microbial volatile organic compounds (MVOC) by means of ion mobility spectroscopy (IMS); Detektion leicht fluechtiger organischer Verbindungen mikrobiellen Ursprungs (MVOC) mittels Ionenmobilitaetsspektrometrie (IMS)

Energy Technology Data Exchange (ETDEWEB)

Tiebe, Carlo

2010-07-01

Traces of microbial volatile organic compounds (MVOCs) can indicate the growth of moulds in the indoor air. The application of ion mobility spectrometry (IMS) is a very promising method for the detection of these MVOCs due to its high sensitivity. A mobile IMS device was tested to use this analytical-chemical method for in situ indoor air diagnostics. The first part of this work describes the test gas generation of 14 MVOCs in the laboratory. The test gases were produced by preparation of permeation procedures. Due to the MVOCs test gases IMS parameters like reduced mobility (K{sub 0}), relative drift time (t{sub rd}), the concentration dependency of MVOCs signals were determined and the limit of detection (LOD) was calculated. The LODs are in the range of 2 to 192 {mu}g m{sup -3} (1 to 51 ppb{sub V}). In the second part of this manuscript seven different mould species were cultivated on nutrient media and their MVOCs emissions were explored. It was found out, that the MVOCs emissions of moulds have a dependency of species and of their cultivation time. These results are confirmed by principal component analysis (PCA). The identification of these MVOCs was performed by test-related GC-MS analysis and approved these results. The MVOCs emissions were explored in the cultivation of mould mixtures on three different building materials. The IMS-results were interpreted chemo metrically by PCA. It was possible to find different emission patterns of cultivated moulds on building materials without an identification of the MVOCs inside the emission chamber. In 27 field trials of different indoor environments (rooms) the IMS was tested to detect MVOCs. In 59 % of the cases a positive correlation is determined between visible mould-infested rooms and the detected MVOCs by IMS. (orig.)

Crystalline maricite NaFePO4 as a positive electrode material for sodium secondary batteries operating at intermediate temperature

Science.gov (United States)

Hwang, Jinkwang; Matsumoto, Kazuhiko; Orikasa, Yuki; Katayama, Misaki; Inada, Yasuhiro; Nohira, Toshiyuki; Hagiwara, Rika

2018-02-01

Maricite NaFePO4 (m-NaFePO4) was investigated as a positive electrode material for intermediate-temperature operation of sodium secondary batteries using ionic liquid electrolytes. Powdered m-NaFePO4 was prepared by a conventional solid-state method at 873 K and subsequently fabricated in two different conditions; one is ball-milled in acetone and the other is re-calcined at 873 K after the ball-milling. Electrochemical properties of the electrodes prepared with the as-synthesized m-NaFePO4, the ball-milled m-NaFePO4, and the re-calcined m-NaFePO4 were investigated in Na[FSA]-[C2C1im][FSA] (C2C1im+ = 1-ethyl-3-methylimidazolium, FSA- = bis(fluorosulfonyl)amide) ionic liquid electrolytes at 298 K and 363 K to assess the effects of temperature and particle size on their electrochemical properties. A reversible charge-discharge capacity of 107 mAh g-1 was achieved with a coulombic efficiency >98% from the 2nd cycle using the ball-milled m-NaFePO4 electrode at a C-rate of 0.1 C and 363 K. Electrochemical impedance spectroscopy using m-NaFePO4/m-NaFePO4 symmetric cells indicated that inactive m-NaFePO4 becomes an active material through ball-milling treatment and elevation of operating temperature. X-ray diffraction analysis of crystalline m-NaFePO4 confirmed the lattice contraction and expansion upon charging and discharging, respectively. These results indicate that the desodiation-sodiation process in m-NaFePO4 is reversible in the intermediate-temperature range.

Environmental trace analysis by means of supersensitive GC-IMS

Energy Technology Data Exchange (ETDEWEB)

Leonhardt, J.W. [IUTLimited, Berlin, (Germany)

1997-10-01

The effective control of pollutants in ambient air requires their fast in situ identification and concentration determination of chemical compounds in the range of micrograms per m{sup 3}. There are attempts to use conventional analytical techniques as portable GC and GC-MS. These systems are relatively expensive. A new supersensitive ion Mobility Sensor (IMS) was developed and checked by IUT Ltd, which meets the new demands. The use of tritium sources is an advantage in comparison with other IMS being equipped by nickel-63, the application of which is rather critical in respect of the radiation protection. On the other hand an integrated separation column allows to reduce interferences by matrix effects. The technical parameters of the IUT GC- IMS and some of its most important applications are briefly presented 6 refs., 1 tab., 5 figs.

[Photoionization ion mobility spectrometry (UV-IMS) for the isomeric volatile organic compounds].

Science.gov (United States)

Li, Hu; Niu, Wen-qi; Wang, Hong-mei; Huang, Chao-qun; Jiang, Hai-he; Chu, Yan-nan

2012-01-01

The construction and performance study is reported for a newly developed ultraviolet photoionization ion mobility spectrometry (UV-IMS). In the present paper, an UV-IMS technique was firstly developed to detect eleven isomeric volatile organic compounds including the differences in the structure of carbon chain, the style of function group and the position of function group. Their reduced mobility values were determined and increased in this order: linears alcohols homemade UV-IMS was around ppb-ppm.

[Einheit und Vielfalt in der Rechtsgeschichte im Ostseeraum] / Marelle Leppik

Index Scriptorium Estoniae

Leppik, Marelle

2013-01-01

Arvustus: Einheit und Vielfalt in der Rechtsgeschichte im Ostseeraum. Unity and plurality in the legal history of the Baltic Sea area Sechster Rechtshistorikertag im Ostseeraum, 3.-5. Juni 2010 Tartu (Estland) / Riga (Lettland9. Hrsg. von Marju Luts-Sootak, Sanita Osipova und Frank L. Schäfer. (Rechtshistorische Reihe, Bd. 428.) Land. Frankfurt am Main u. a. 2012

Frauen im Netz weltweit – ausgegrenzt und mittendrin

Directory of Open Access Journals (Sweden)

Sigrid Peuker

2003-03-01

Full Text Available Mit dem Global Center for Women’s Studies and Politics (GLOW ist das Feministische Institut der Heinrich-Böll-Stiftung 1998 online gegangen. Mit diesem Schritt wurden Fragen nach den Möglichkeiten und Grenzen sowie nach den Gestaltungsräumen virtueller Kommunikation für Frauen zentral. Mit feminist_spaces. Frauen im Netz. Diskurse – Communities – Visionen, legt die Heinrich-Böll-Stiftung zusammen mit dem Feministischen Institut Antworten aus internationaler Perspektive vor. Das Buch geht auf die gleichnamige zweitätige Konferenz in Berlin im November 2001 zurück.

Cosmic abundances: The impact of stellar duplicity

OpenAIRE

Jorissen, A.; Van Eck, S.

2004-01-01

The mass-transfer scenario links chemical peculiarities with stellar duplicity for an increasing number of stellar classes (classical and dwarf barium stars, subgiant and giant CH stars, S stars without technetium, yellow symbiotic stars, WIRRING stars, Abell-35-like nuclei of planetary nebulae...). Despite these successes, the mass-transfer scenario still faces several problems: What is the mass-transfer mode? Why orbital elements of dwarf barium stars do not fully match those of the classic...

MID Max: LC–MS/MS Method for Measuring the Precursor and Product Mass Isotopomer Distributions of Metabolic Intermediates and Cofactors for Metabolic Flux Analysis Applications

DEFF Research Database (Denmark)

McCloskey, Douglas; Young, Jamey D.; Xu, Sibei

2016-01-01

The analytical challenges to acquire accurate isotopic data of intracellular metabolic intermediates for stationary, nonstationary, and dynamic metabolic flux analysis (MFA) are numerous. This work presents MID Max, a novel LC–MS/MS workflow, acquisition, and isotopomer deconvolution method for MFA...... that takes advantage of additional scan types that maximizes the number of mass isotopomer distributions (MIDs) that can be acquired in a given experiment. The analytical method was found to measure the MIDs of 97 metabolites, corresponding to 74 unique metabolite-fragment pairs (32 precursor spectra and 42...

Unconventional actin conformations localize on intermediate filaments in mitosis

International Nuclear Information System (INIS)

Hubert, Thomas; Vandekerckhove, Joel; Gettemans, Jan

2011-01-01

Research highlights: → Unconventional actin conformations colocalize with vimentin on a cage-like structure in metaphase HEK 293T cells. → These conformations are detected with the anti-actin antibodies 1C7 ('lower dimer') and 2G2 ('nuclear actin'), but not C4 (monomeric actin). → Mitotic unconventional actin cables are independent of filamentous actin or microtubules. → Unconventional actin colocalizes with vimentin on a nocodazole-induced perinuclear dense mass of cables. -- Abstract: Different structural conformations of actin have been identified in cells and shown to reside in distinct subcellular locations of cells. In this report, we describe the localization of actin on a cage-like structure in metaphase HEK 293T cells. Actin was detected with the anti-actin antibodies 1C7 and 2G2, but not with the anti-actin antibody C4. Actin contained in this structure is independent of microtubules and actin filaments, and colocalizes with vimentin. Taking advantage of intermediate filament collapse into a perinuclear dense mass of cables when microtubules are depolymerized, we were able to relocalize actin to such structures. We hypothesize that phosphorylation of intermediate filaments at mitosis entry triggers the recruitment of different actin conformations to mitotic intermediate filaments. Storage and partition of the nuclear actin and antiparallel 'lower dimer' actin conformations between daughter cells possibly contribute to gene transcription and transient actin filament dynamics at G1 entry.

Consideraciones sobre el diagnóstico por imágenes de las masas selares Reflection on imaging diagnosis of sellar masses

Directory of Open Access Journals (Sweden)

José Arturo Hernández Yero

2005-12-01

Full Text Available Con el propósito de hacer un llamado de atención sobre una temática de importancia y tomando en consideración que con los avances en la imagenología moderna se aportan elementos distintivos y de gran utilidad en el diagnóstico por imágenes de un grupo de masas en la región de la silla turca, se hacen determinadas valoraciones al respecto, con precisión de algunas de las características de las principales masas selares y su apariencia en la resonancia magnética nuclear. Se destacan detalles en cuanto a la intensidad de la señal en los adenomas pituitarios, craneofaringiomas, quistes de la bolsa de Rathke, hiperplasia hipofisaria y el denominado síndrome de la silla turca vacía, entre otras causas de cambios anatómicos en la región selar. Se concluye que la imagen por resonancia magnética nuclear sería el método idóneo para un mejor diagnóstico de las masas selares aunque, en ausencia de esta, la tomografía contrastada puede resultar de utilidad si se realiza con cortes menores de 2 mm. Se resalta la importancia de integrar un equipo multidisciplinario entre clínicos, endocrinólogos, imagenólogos, neurocirujanos y anatomopatólogos, para obtener diagnósticos más precisos y resultados terapéuticos adecuados.Some reflections were made on imaging diagnosis of sellar masses, specifying some characteristics of the main sellar masses and their appearance in magnetic resonance imaging. The purpose was to call the attention on this important issue on the basis that modern imaging advances offer very useful distinctive elements in the diagnosis of a group of masses located in the sella turcica region. The paper underlined details of signal intensity in pituitary adenomas, craniopharyngiomas, Rathke´s pouch cysts, hypophysial hyperplasia and the so-called empty sella syndrome, among other causes of anatomical changes in sellar region. It was concluded that magnetic resonance imaging would be the ideal method for a better

Heat and mass transfer analysis intermediate temperature solid oxide fuel cells (IT-SOFC)

International Nuclear Information System (INIS)

Timurkutluk, B.; Mat, M. M.; Kaplan, Y.

2007-01-01

Solid oxide fuel cells (SOFCs) have been considered as next generation energy conversion system due to their high efficiency, clean and quite operation with fuel flexibility. To date, yittria stabilized zirconia (YSZ) electrolytes have been mainly used for SOFC applications at high temperatures around 1000 degree C because of their high ionic conductivity, chemical stability and good mechanical properties. However, such a high temperature is undesirable for fuel cell operations in the viewpoint of stability. Moreover, high operation temperature necessitates high cost interconnect and seal materials. Thus, the reduction in the operation temperature of SOFCs is one of the key issues in the aspects of the cost reduction and the long term operation without degradation as well as commercialization of the SOFC systems. With the reducing temperature, not only low cost stainless steels and glass materials can be used as interconnect and sealing materials respectively but the manufacturing technology will also extend. Therefore, the design of complex geometrical SOFC component will also be possible. One way to reduce the operation temperature of SOFC is use of an alternative electrolyte material to YSZ showing acceptable properties at intermediate temperatures (600-800 degree C). As being one of IT-SOFC electrolyte materials, gadolinium doped ceria (GDC) has been taken great deals. In this study, a mathematical model for mass and heat transfer for a single cell GDC electrolyte SOFC system was developed and numerical solutions were evaluated. In order to verify the mathematical model, set of experiments were performed by taking species from four different samples randomly and five various temperature measurements. The numerical results reasonably agree with experimental data

Associations between United States Medical Licensing Examination (USMLE) and Internal Medicine In-Training Examination (IM-ITE) scores.

Science.gov (United States)

McDonald, Furman S; Zeger, Scott L; Kolars, Joseph C

2008-07-01

Little is known about the associations of previous standardized examination scores with scores on subsequent standardized examinations used to assess medical knowledge in internal medicine residencies. To examine associations of previous standardized test scores on subsequent standardized test scores. Retrospective cohort study. One hundred ninety-five internal medicine residents. Bivariate associations of United States Medical Licensing Examination (USMLE) Steps and Internal Medicine In-Training Examination (IM-ITE) scores were determined. Random effects analysis adjusting for repeated administrations of the IM-ITE and other variables known or hypothesized to affect IM-ITE score allowed for discrimination of associations of individual USMLE Step scores on IM-ITE scores. In bivariate associations, USMLE scores explained 17% to 27% of the variance in IME-ITE scores, and previous IM-ITE scores explained 66% of the variance in subsequent IM-ITE scores. Regression coefficients (95% CI) for adjusted associations of each USMLE Step with IM-ITE scores were USMLE-1 0.19 (0.12, 0.27), USMLE-2 0.23 (0.17, 0.30), and USMLE-3 0.19 (0.09, 0.29). No single USMLE Step is more strongly associated with IM-ITE scores than the others. Because previous IM-ITE scores are strongly associated with subsequent IM-ITE scores, appropriate modeling, such as random effects methods, should be used to account for previous IM-ITE administrations in studies for which IM-ITE score is an outcome.

Wir und die Anderen: Gruppenbezogene Menschenfeindlichkeit im Sport in Sachsen

OpenAIRE

Delto, Hannes; Tzschoppe, Petra

2015-01-01

Mit der Querschnittsstudie "Wir und die Anderen – Gruppenbezogene Menschenfeindlichkeit im organisierten Sport in Sachsen" wurde erstmals das Syndrom Gruppenbezogener Menschenfeindlichkeit im organisierten Sport untersucht. Das Konzept der Gruppenbezogenen Menschenfeindlichkeit – ausgehend von einer Ideologie der Ungleichwertigkeit – wurde von Prof. Wilhelm Heitmeyer (Universität Bielefeld) entwickelt. Die Ergebnisse ermöglichen explizite Aussagen über Ausmaß und Ursachen Gruppenbezogener Men...

Information management system study results. Volume 1: IMS study results

Science.gov (United States)

1971-01-01

The information management system (IMS) special emphasis task was performed as an adjunct to the modular space station study, with the objective of providing extended depth of analysis and design in selected key areas of the information management system. Specific objectives included: (1) in-depth studies of IMS requirements and design approaches; (2) design and fabricate breadboard hardware for demonstration and verification of design concepts; (3) provide a technological base to identify potential design problems and influence long range planning (4) develop hardware and techniques to permit long duration, low cost, manned space operations; (5) support SR&T areas where techniques or equipment are considered inadequate; and (6) permit an overall understanding of the IMS as an integrated component of the space station.

Grand Prix Eurovision: Eine Fankultur im Medienzeitalter

Directory of Open Access Journals (Sweden)

Heinz Moser

2017-06-01

Full Text Available Der Grand Prix Eurovision ist seit Jahrzehnten eine der bekanntesten Unterhaltungssendungen im europäischen Raum. Dennoch erregte es Verwunderung, wenn der Schreibende Bekannten darüber berichtete, daß dies ein Forschungsgegenstand sei. Wurde von Interviews mit Grand Prix-Fans erzählt, so fielen schnell Aussagen wie: „Wie kann man sich nur für so etwas Abseitiges und Triviales wie den Grand Prix interessieren“. Dennoch bin ich der Meinung, daß Fankulturen für die entstehende Mediengesellschaft ein nicht unwichtiges Forschungsthema darstellen. Zwar geht es nicht um eine medienpädagogische Fragestellung im engeren Sinne; die Fans des Grand Prix Eurovision sind dem Jugendalter längst entwachsen. Dennoch handelt es sich bei Fangemeinschaften um Phänomene, die im Rahmen von Jugend- und Kinderkulturen von besonderer Relevanz sind. So meint Winter (1997, daß jugendliche Fanwelten eine bedeutende Rolle als Kristallisationspunkte kultureller Differenzierung spielen: ,Die Zugehörigkeit zu einer Fan weit ist Teil der jugendlichen Lebensbewältigung in der Postmoderne, denn in der Gemeinschaft der Fans können Jugendliche emotionale Allianzen eingehen, außeralltäglichen Beschäftigungen nachgehen, expressive Identitätsmuster gemeinschaftlich realisieren und sich mit ihrer Lebenssituation als Heranwachsende auseinandersetzen“ (Winter 1997, S. 51f..

The expression profile of phosphatidylinositol in high spatial resolution imaging mass spectrometry as a potential biomarker for prostate cancer.

Directory of Open Access Journals (Sweden)

Takayuki Goto

Full Text Available High-resolution matrix-assisted laser desorption/ionization imaging mass spectrometry (HR-MALDI-IMS is an emerging application for the comprehensive and detailed analysis of the spatial distribution of ionized molecules in situ on tissue slides. HR-MALDI-IMS in negative mode in a mass range of m/z 500-1000 was performed on optimal cutting temperature (OCT compound-embedded human prostate tissue samples obtained from patients with prostate cancer at the time of radical prostatectomy. HR-MALDI-IMS analysis of the 14 samples in the discovery set identified 26 molecules as highly expressed in the prostate. Tandem mass spectrometry (MS/MS showed that these molecules included 14 phosphatidylinositols (PIs, 3 phosphatidylethanolamines (PEs and 3 phosphatidic acids (PAs. Among the PIs, the expression of PI(18:0/18:1, PI(18:0/20:3 and PI(18:0/20:2 were significantly higher in cancer tissue than in benign epithelium. A biomarker algorithm for prostate cancer was formulated by analyzing the expression profiles of PIs in cancer tissue and benign epithelium of the discovery set using orthogonal partial least squares discriminant analysis (OPLS-DA. The sensitivity and specificity of this algorithm for prostate cancer diagnosis in the 24 validation set samples were 87.5 and 91.7%, respectively. In conclusion, HR-MALDI-IMS identified several PIs as being more highly expressed in prostate cancer than benign prostate epithelium. These differences in PI expression profiles may serve as a novel diagnostic tool for prostate cancer.

Down-conversion IM-DD RF photonic link utilizing MQW MZ modulator.

Science.gov (United States)

Xu, Longtao; Jin, Shilei; Li, Yifei

2016-04-18

We present the first down-conversion intensity modulated-direct detection (IM-DD) RF photonic link that achieves frequency down-conversion using the nonlinear optical phase modulation inside a Mach-Zehnder (MZ) modulator. The nonlinear phase modulation is very sensitive and it can enable high RF-to-IF conversion efficiency. Furthermore, the link linearity is enhanced by canceling the nonlinear distortions from the nonlinear phase modulation and the MZ interferometer. Proof-of-concept measurement was performed. The down-conversion IM-DD link demonstrated 28dB improvement in distortion levels over that of a conventional IM-DD link using a LiNbO3 MZ modulator.

Intermediate treatments

Science.gov (United States)

John R. Jones; Wayne D. Shepperd

1985-01-01

Intermediate treatments are those applied after a new stand is successfully established and before the final harvest. These include not only intermediate cuttings - primarily thinning - but also fertilization, irrigation, and protection of the stand from damaging agents.

Results from an Interval Management (IM) Flight Test and Its Potential Benefit to Air Traffic Management Operations

Science.gov (United States)

Baxley, Brian; Swieringa, Kurt; Berckefeldt, Rick; Boyle, Dan

2017-01-01

NASA's first Air Traffic Management Technology Demonstration (ATD-1) subproject successfully completed a 19-day flight test of an Interval Management (IM) avionics prototype. The prototype was built based on IM standards, integrated into two test aircraft, and then flown in real-world conditions to determine if the goals of improving aircraft efficiency and airport throughput during high-density arrival operations could be met. The ATD-1 concept of operation integrates advanced arrival scheduling, controller decision support tools, and the IM avionics to enable multiple time-based arrival streams into a high-density terminal airspace. IM contributes by calculating airspeeds that enable an aircraft to achieve a spacing interval behind the preceding aircraft. The IM avionics uses its data (route of flight, position, etc.) and Automatic Dependent Surveillance-Broadcast (ADS-B) state data from the Target aircraft to calculate this airspeed. The flight test demonstrated that the IM avionics prototype met the spacing accuracy design goal for three of the four IM operation types tested. The primary issue requiring attention for future IM work is the high rate of IM speed commands and speed reversals. In total, during this flight test, the IM avionics prototype showed significant promise in contributing to the goals of improving aircraft efficiency and airport throughput.

A critical analysis of Sorrell v. IMS Health, Inc.: Pandora's box at best.

Science.gov (United States)

Bibet-Kalinyak, Isabelle

2012-01-01

Sorrell v. IMS Health, Inc. ("IMS Health"), a remarkable health care case with resounding First Amendment and economic repercussions, features the clashing interests of the State of Vermont and aggressive free market players from the pharmaceutical and data mining industries in a constitutional battle over Free Speech. In 2007, Vermont enacted Act 80, The Confidentiality of Prescription Information Act, prohibiting the sale, disclosure, and use of pharmacy records. Together with two other data miners and PhRMA, an association of brand-name drug manufacturers, IMS Health successfully challenged the constitutionality of Act 80 on First Amendment grounds. This article examines the legal arguments of IMS Health and Act 80 and analyzes why IMS Health stands out for potentially challenging the traditional doctrine of commercial speech and the resulting legal implications. After reviewing the Supreme Court's reasoning, the article concludes that, although the Supreme Court reached the appropriate outcome, it did so by unjustifiably departing from the established legal doctrine of commercial speech and the American tradition of consumer protection. At best, IMS Health's reasoning opens a legal Pandora's Box potentially leading to an onset of new commercial speech challenges; at worst, it manufactured a Trojan Horse aimed at eroding the traditional regulatory safeguards that maintain a balance between the needs of consumers and corporations alike.

Innovative Techniken und Algorithmen im Bereich Computational-Finance und Risikomanagement

OpenAIRE

Liang, Qian

2012-01-01

Diese Dissertation besteht aus zwei aktuellen Themen im Bereich Finanzmathematik, die voneinander unabhängig sind. Beim ersten Thema, "Flexible Algorithmen zur Bewertung komplexer Optionen mit mehreren Eigenschaften mittels der funktionalen Programmiersprache Haskell", handelt es sich um ein interdisziplinäres Projekt, in dem eine wissenschaftliche Brücke zwischen der Optionsbewertung und der funktionalen Programmierung geschlagen wurde. Im diesem Projekt wurde eine funktionale Biblio...

Die Raumdarstellung im erzählenden Werk um 1900

OpenAIRE

Lu, Xiaoli

2011-01-01

In der Literatur existiert eine eigene Welt, die mit Raum und Zeit verbunden ist. Im 19. Jahrhundert gewinnen beide, Raum und Zeit, an Bedeutung als bewusst eingesetzte Gestaltungselemente. Es bilden sich zwei Grundrichtungen heraus, eine mit dem Erzählgeschehen verknüpfte Semantisierung in der Klassik und in der Romantik und eine betonte Fixierung des Geschehens in der realen Welt durch genaue Zeit- und Ortsangaben im Realismus. Die Semantisierung von Raum und Zeit führt zu einer Bedeutungss...

[Das Bild und die Wahrnehmung der Stadt und der städtischen Gesellschaft im Hanseraum im Mittelalter und in der frühen Neuzeit] / Juhan Kreem

Index Scriptorium Estoniae

Kreem, Juhan

2009-01-01

Arvustus: Das Bild und die Wahrnehmung der Stadt und der städtischen Gesellschaft im Hanseraum im Mittelalter und in der frühen Neuzeit. hrsg. v. Roman Czaja. Torun, 2004. Torunis 2002. aastal toimunud konverentsi materjalid. Projekti "Pilt ja linn" raames ilmunud publikatsioonide loendit saab näha aadressil http://www.historiaurbium.org/english/attivita_images_en.html.

IMS Mitigation Target Areas - 2010 [ds673

Data.gov (United States)

California Natural Resource Agency — Mitigation Target Areas (MTA) were developed by the California Department of Fish and Game for the Interim Mitigation Strategy (IMS). The MTAs are an identification...

The distribution of {sup 236}U/{sup 238}U in the North Atlantic and adjacent oceans; Die Verteilung von {sup 236}U/{sup 238}U im Nordatlantik und den angrenzenden Ozeanen

Energy Technology Data Exchange (ETDEWEB)

Christl, Marcus; Casacuberta, Nuria; Lachner, Johannes; Maxeiner, Sascha; Vockenhuber, Christof; Synal, Hans-Arno [Labor fuer Ionenstrahlphysik, ETH Zuerich (Switzerland); Herrmann, Juergen [Bundesamt fuer Seeschifffahrt und Hydroghraphie, Hamburg (Germany); Castrillejo, Maxi; Masque, Pere [Universitat Autonoma de Barcelona (Spain); Rutgers van der Loeff, Michiel [Alfred-Wegener-Institut, Bremerhaven (Germany)

2015-07-01

The technical developments of recent years, such as the introduction of helium as a stripping gas, make compact AMS systems probably among the most sensitive analyzers available for ultra-trace analyzes of actinides in the environment. Such systems are particularly suitable for the trace analysis of {sup 236}U since conventional mass spectrometry does not provide the necessary suppression of the substrate caused by molecules or neighboring masses. Over the past few years, unique data sets of {sup 236}U/{sup 238}U have been produced at the AMS System Tandy of the ETH Zurich in the Atlantic and Arctic Ocean as well as in the Mediterranean and the North Sea. This lecture will provide a brief overview of the latest technical developments in the field of heavy ion analysis at compact AMS plants at ETH Zurich. In the second part, the produced data sets are then assembled and the current understanding of this new ocean tracer discussed. [German] Die technischen Entwicklungen der letzten Jahre, wie zum Beispiel die Einfuehrung von Helium als stripper Gas, machen kompakte AMS Systeme wahrscheinlich zu den sensitivsten verfuegbaren Analysegeraeten fuer Ultra-Spurenstoffanalysen von Aktiniden in der Umwelt. Solche Systeme eignen sich im Besonderen zur Spurenanalyse von {sup 236}U, da konventionelle Massenspektrometrie hier nicht die erforderliche Unterdrueckung des durch Molekuele oder Nachbarmassen verursachten Untergrundes bietet. Am AMS System Tandy der ETH Zuerich wurden waehrend der letzten Jahre einzigartige Datensaetze von {sup 236}U/{sup 238}U im Atlantischen und Arktischen Ozean, sowie im Mittelmeer und der Nordsee produziert. In diesem Vortrag soll zunaechst ein kurzer Ueberblick ueber die neuesten technischen Entwicklungen im Bezug auf Schwerionen Analysen an kompakten AMS Anlagen der ETH Zuerich gegeben werden. Im zweiten Teil werden dann die produzierten Datensaetze zusammengefuegt und das gegenwaertige Verstaendnis dieses neuen Ozean-Tracers diskutiert.

Observation of an intermediate state in psi (3684) radiative cascade decay

International Nuclear Information System (INIS)

Tanenbaum, W.; Whitaker, J.S.; Abrams, G.S.; Boyarski, A.M.; Breidenbach, M.; Bulos, F.; Chinowsky, W.; Feldman, G.J.; Friedberg, C.E.; Fryberger, D.; Goldhaber, G.; Hanson, G.; Hartill, D.L.; Jean-Marie, B.; Kadyk, J.A.; Larsen, R.R.; Litke, A.M.; Luke, D.; Lulu, B.A.; Luth, V.; Lynch, H.L.; Morehouse, C.C.; Paterson, J.M.; Perl, M.L.; Pierre, F.M.; Pun, T.P.; Rapidis, P.; Richter, B.; Sadoulet, B.; Schwitters, R.F.; Trilling, G.H.; Vannucci, F.; Winkelmann, F.C.; Wiss, J.E.

1975-01-01

We present evidence for the existence of an intermediate state observed in the decay sequence psi(3684) → psi(3095)γγ. The mass of the state is either 3500+-10 or 3270+-10 MeV. The branching fraction of the sequence is (3.6+-0.7)%

Magnetized Converging Flows toward the Hot Core in the Intermediate/High-mass Star-forming Region NGC 6334 V

Energy Technology Data Exchange (ETDEWEB)

Juárez, Carmen; Girart, Josep M. [Institut de Ciències de l’Espai, (CSIC-IEEC), Campus UAB, Carrer de Can Magrans, S/N, E-08193 Cerdanyola del Vallès, Catalonia (Spain); Zamora-Avilés, Manuel; Palau, Aina; Ballesteros-Paredes, Javier [Instituto de Radioastronomía y Astrofísica, Universidad Nacional Autónoma de México, P.O. Box 3-72, 58090, Morelia, Michoacán (Mexico); Tang, Ya-Wen; Koch, Patrick M.; Liu, Hauyu Baobab [Academia Sinica Institute of Astronomy and Astrophysics, P.O. Box 23-141, Taipei, 10617, Taiwan (China); Zhang, Qizhou [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Qiu, Keping, E-mail: juarez@ice.cat [School of Astronomy and Space Science, Nanjing University, 163 Xianlin Avenue, Nanjing 210023 (China)

2017-07-20

We present Submillimeter Array (SMA) observations at 345 GHz toward the intermediate/high-mass cluster-forming region NGC 6334 V. From the dust emission we spatially resolve three dense condensations, the brightest one presenting the typical chemistry of a hot core. The magnetic field (derived from the dust polarized emission) shows a bimodal converging pattern toward the hot core. The molecular emission traces two filamentary structures at two different velocities, separated by 2 km s{sup −1}, converging to the hot core and following the magnetic field distribution. We compare the velocity field and the magnetic field derived from the SMA observations with magnetohydrodynamic simulations of star-forming regions dominated by gravity. This comparison allows us to show how the gas falls in from the larger-scale extended dense core (∼0.1 pc) of NGC 6334 V toward the higher-density hot core region (∼0.02 pc) through two distinctive converging flows dragging the magnetic field, whose strength seems to have been overcome by gravity.

Hinderniserkennung und -verfolgung mit einer PMD-kamera im automobil

Science.gov (United States)

Schamm, Thomas; Vacek, Stefan; Natroshvilli, Koba; Marius Zöllner, J.; Dillmann, Rüdiger

Die Detektion von Hindernissen vor dem Automobil ist eine Hauptanforderung an moderne Fahrerassistenzsysteme (FAS). In dieser Arbeit wird ein System vorgestellt, das mit Hilfe einer PMDKamera (Photomischdetektor) Hindernisse auf der Fahrspur erkennt und deren relevante Parameter bestimmt. Durch die PMD-Kamera werden zunächst 3D-Tiefenbilder der Fahrzeugumwelt generiert. Nach einem initialen Filterprozess werden im Tiefenbild mit Hilfe eines Bereichswachstumsverfahrens Hindernisse gesucht. Zur Stabilisierung des Verfahrens und zur Parameterberechnung wird ein Kaiman Filter eingesetzt. Das Ergebnis ist eine Liste aller Hindernisse im Fahrbereich des Automobils.

[Christian Westerhoff. Zwangsarbeit im Ersten Weltkrieg. Deutsche Arbeitskräftepolitik im besetzten Polen und Litauen 1914-1918, Tilman Plath.Zwischen Schonung und Menschenjagden. Die Arbeitseinsatzpolitik in den baltischen Generalbezirken des Reich

Index Scriptorium Estoniae

Hiio, Toomas, 1965-

2014-01-01

Arvustus: Westerhoff, Christian. Zwangsarbeit im Ersten Weltkrieg. Deutsche Arbeitskräftepolitik im besetzten Polen und Litauen 1914-1918 (Studien zur historischen Migrationsforschung, 25). Verlag Ferdinand Schöningh. Padeborn 2011

THE METALLICITY EVOLUTION OF BLUE COMPACT DWARF GALAXIES FROM THE INTERMEDIATE REDSHIFT TO THE LOCAL UNIVERSE

International Nuclear Information System (INIS)

Lian, Jianhui; Hu, Ning; Ye, Chengyun; Kong, Xu; Fang, Guanwen

2016-01-01

We present oxygen abundance measurements for 74 blue compact dwarf (BCD) galaxies in the redshift range of [0.2, 0.5] using the strong-line method. The spectra of these objects are taken using Hectospec on the Multiple Mirror Telescope. More than half of these BCDs had dust attenuation corrected using the Balmer decrement method. For comparison, we also selected a sample of 2023 local BCDs from the Sloan Digital Sky Survey (SDSS) database. Based on the local and intermediate-z BCD samples, we investigated the cosmic evolution of the metallicity, star formation rate (SFR), and D n (4000) index. Compared with local BCDs, the intermediate-z BCDs had a systematically higher R23 ratio but a similar O32 ratio. Interestingly, no significant deviation in the mass–metallicity (MZ) relation was found between the intermediate-z and local BCDs. Besides the metallicity, the intermediate-z BCDs also exhibited an SFR distribution that was consistent with local BCDs, suggesting a weak dependence on redshift. The intermediate-z BCDs seemed to be younger than the local BCDs with lower D n (4000) index values. The insignificant deviation in the mass–metallicity and mass–SFR relations between intermediate-z and local BCDs indicates that the relations between the global parameters of low-mass compact galaxies may be universal. These results from low-mass compact galaxies could be used to place important observational constraints on galaxy formation and evolution models

THE METALLICITY EVOLUTION OF BLUE COMPACT DWARF GALAXIES FROM THE INTERMEDIATE REDSHIFT TO THE LOCAL UNIVERSE

Energy Technology Data Exchange (ETDEWEB)

Lian, Jianhui; Hu, Ning; Ye, Chengyun; Kong, Xu [CAS Key Laboratory for Research in Galaxies and Cosmology, Department of Astronomy, University of Science and Technology of China, Hefei, Anhui 230026 (China); Fang, Guanwen, E-mail: ljhhw@mail.ustc.edu.cn, E-mail: xkong@ustc.edu.cn [Institute for Astronomy and History of Science and Technology, Dali University, Dali 671003 (China)

2016-03-01

We present oxygen abundance measurements for 74 blue compact dwarf (BCD) galaxies in the redshift range of [0.2, 0.5] using the strong-line method. The spectra of these objects are taken using Hectospec on the Multiple Mirror Telescope. More than half of these BCDs had dust attenuation corrected using the Balmer decrement method. For comparison, we also selected a sample of 2023 local BCDs from the Sloan Digital Sky Survey (SDSS) database. Based on the local and intermediate-z BCD samples, we investigated the cosmic evolution of the metallicity, star formation rate (SFR), and D{sub n}(4000) index. Compared with local BCDs, the intermediate-z BCDs had a systematically higher R23 ratio but a similar O32 ratio. Interestingly, no significant deviation in the mass–metallicity (MZ) relation was found between the intermediate-z and local BCDs. Besides the metallicity, the intermediate-z BCDs also exhibited an SFR distribution that was consistent with local BCDs, suggesting a weak dependence on redshift. The intermediate-z BCDs seemed to be younger than the local BCDs with lower D{sub n}(4000) index values. The insignificant deviation in the mass–metallicity and mass–SFR relations between intermediate-z and local BCDs indicates that the relations between the global parameters of low-mass compact galaxies may be universal. These results from low-mass compact galaxies could be used to place important observational constraints on galaxy formation and evolution models.

Coupling Front-End Separations, Ion Mobility Spectrometry, and Mass Spectrometry For Enhanced Multidimensional Biological and Environmental Analyses

Science.gov (United States)

Zheng, Xueyun; Wojcik, Roza; Zhang, Xing; Ibrahim, Yehia M.; Burnum-Johnson, Kristin E.; Orton, Daniel J.; Monroe, Matthew E.; Moore, Ronald J.; Smith, Richard D.; Baker, Erin S.

2017-01-01

Ion mobility spectrometry (IMS) is a widely used analytical technique for rapid molecular separations in the gas phase. Though IMS alone is useful, its coupling with mass spectrometry (MS) and front-end separations is extremely beneficial for increasing measurement sensitivity, peak capacity of complex mixtures, and the scope of molecular information available from biological and environmental sample analyses. In fact, multiple disease screening and environmental evaluations have illustrated that the IMS-based multidimensional separations extract information that cannot be acquired with each technique individually. This review highlights three-dimensional separations using IMS-MS in conjunction with a range of front-end techniques, such as gas chromatography, supercritical fluid chromatography, liquid chromatography, solid-phase extractions, capillary electrophoresis, field asymmetric ion mobility spectrometry, and microfluidic devices. The origination, current state, various applications, and future capabilities of these multidimensional approaches are described in detail to provide insight into their uses and benefits. PMID:28301728

Toward an Intelligent Ion Mobility Spectrometer (IMS)

International Nuclear Information System (INIS)

McJunkin, Timothy R.; Scott, Jill R.; Miller, Carla J.

2003-01-01

The ultimate goal is to design and build a very smart ion mobility spectrometer (IMS) that can operate autonomously. To accomplish this, software capable of interpreting spectra so that it can be used in control loops for data interpretation as well as adjusting instrument parameters is being developed. Fuzzy logic and fuzzy numbers are used in this IMS spectra classification scheme. Fuzzy logic provides a straight forward method for developing a classification/detection system, whenever rules for classifying the spectra can be described linguistically. Instead of using 'max' and 'min' values, the product of the truth values is used to determine class membership. Using the product allows rule-bases that utilize the AND function to allow each condition to discount truth value in determining membership, while rule-bases with an OR function are allowed to accumulate membership. Fuzzy numbers allow encapsulation of the uncertainties due to ion mobility peak widths as well as measured instrumental parameters, such as pressure and temperature. Associating a peak with a value of uncertainty, in addition to making adjustments to the mobility calculation based on variations in measured parameters, enables unexpected shifts to be more reliably detected and accounted for; thereby, reducing the opportunity for 'false negative' results. The measure of uncertainty is anticipated to serve the additional purpose of diagnosing the operational conditions of the IMS instrument.

Improved detection of Mycobacterium bovis infection in bovine lymph node tissue using immunomagnetic separation (IMS-based methods.

Directory of Open Access Journals (Sweden)

Linda D Stewart

Full Text Available Immunomagnetic separation (IMS can selectively isolate and concentrate Mycobacterium bovis cells from lymph node tissue to facilitate subsequent detection by PCR (IMS-PCR or culture (IMS-MGIT. This study describes application of these novel IMS-based methods to test for M. bovis in a survey of 280 bovine lymph nodes (206 visibly lesioned (VL, 74 non-visibly lesioned (NVL collected at slaughter as part of the Northern Ireland bovine TB eradication programme. Their performance was evaluated relative to culture. Overall, 174 (62.1% lymph node samples tested positive by culture, 162 (57.8% by IMS-PCR (targeting IS6110, and 191 (68.2% by IMS-MGIT culture. Twelve (6.9% of the 174 culture positive lymph node samples were not detected by either of the IMS-based methods. However, an additional 79 M. bovis positive lymph node samples (27 (13.1% VL and 52 (70.3% NVL were detected by the IMS-based methods and not by culture. When low numbers of viable M. bovis are present in lymph nodes (e.g. in NVLs of skin test reactor cattle decontamination prior to culture may adversely affect viability, leading to false negative culture results. In contrast, IMS specifically captures whole M. bovis cells (live, dead or potentially dormant which are not subject to any deleterious treatment before detection by PCR or MGIT culture. During this study only 2.7% of NVL lymph nodes tested culture positive, whereas 70.3% of the same samples tested M. bovis positive by the IMS-based tests. Results clearly demonstrate that not only are the IMS-based methods more rapid but they have greater detection sensitivity than the culture approach currently used for the detection of M. bovis infection in cattle. Adoption of the IMS-based methods for lymph node testing would have the potential to improve M. bovis detection in clinical samples.

Fission in intermediate energy heavy ion reactions

International Nuclear Information System (INIS)

Wilhelmy, J.B.; Begemann-Blaich, M.; Blaich, T.; Boissevain, J.; Fowler, M.M.; Gavron, A.; Jacak, B.V.; Lysaght, P.S.; Britt, H.C.; Fields, D.J.; Hansen, L.F.; Lanier, R.G.; Massoletti, D.J.; Namboodiri, M.M.; Remington, B.A.; Sangster, T.C.; Struble, G.L.; Webb, M.L.; Chan, Y.D.; Dacai, A.; Harmon, A.; Leyba, J.; Pouliot, J.; Stokstad, R.G.; Hansen, O.; Levine, M.J.; Thorn, C.E.; Trautmann, W.; Dichter, B.; Kaufman, S.; Videbaek, F.; Fraenkel, Z.; Mamane, G.; Cebra, D.; Westfall, G.D.

1989-01-01

A systematic study of reaction mechanisms at intermediate energies (50-100 MeV/A) has been performed at the Lawrence Berkeley Laboratory's BeValac using medium weight projectiles on medium and heavy element targets. A gas and plastic phoswich detector system was employed which gave large geometric coverage and a wide dynamic response. The particles identified with the gas detectors could be characterized into three components - intermediate mass fragments (IMF), fission fragments (FF) and heavy residues (HR). Major observed features are: The reaction yields are similar in the 50 to 100 MeV/A range, central collisions have high multiplicty of IMF's with broad angular correlations consistent with a large participant region, effects of final state Coulomb interactions are observed and give information on the size and temporal behavior of the source, true fission yields are dependent on target fissility and correlated with relatively peripheral collisions. Analysis of fission and evaporation yields implies limiting conditions for which fission decay remains a viable deexcitation channel. (orig.)

Fission in intermediate energy heavy ion reactions

International Nuclear Information System (INIS)

Wilhelmy, J.B.; Begemann-Blaich, M.; Blaich, T.

1989-01-01

A systematic study of reaction mechanisms at intermediate energies (50--100 MeV/A) has been performed at the Lawrence Berkeley Laboratory's BeValac using medium weight projectiles on medium and heavy element targets. A gas and plastic phoswich detector system was employed which gave large geometric coverage and a wide dynamic response. The particles identified with the gas detectors could be characterized into three components - intermediate mass fragments (IMF), fission fragments (FF) and heavy residues (HR). Major observed features are: the reaction yields are similar in the 50 to 100 MeV/A range, central collisions have high multiplicity of IMF's with broad angular correlations consistent with a large participant region, effects of final state Coulomb interactions are observed and give information on the size and temporal behavior of the source, true fission yields are dependent on target fissility and correlated with relatively peripheral collisions. Analysis of fission and evaporation yields implies limiting conditions for which fission decay remains a viable deexcitation channel. 7 figs

Die emotionale Dimension während der Sprechproduktion im Fremdsprachenlernprozess

Directory of Open Access Journals (Sweden)

Bahar İŞİGÜZEL

2017-12-01

Full Text Available Die Gefühle bzw. Emotionen der Lernenden beim Fremdsprachenlehr- und Lernprozess spielen eine wichtige Rolle. Mit der Verknüpfung der Emotion und Kognition beim Lernprozess, haben die positiven Gefühle eine große Bedeutung für den Lernerfolg. Als eine produktive Fertigkeit hat das Sprechen eine wesentlich intensive Beziehung mit den Emotionen, weil es in der realen Zeit fließend laufen muss. Der Lernende soll bei der Sprechproduktion spontan die richtigen Wörter auf die richtige Art und Weise anwenden und sie auch noch verständlich aussprechen. Leider erreicht die Sprechfertigkeit meistens eine niedrigere Niveaustufe als die anderen drei (Schreiben, Lesen und Hören Fertigkeiten im Fremdsprachenunterrichtprozess. Diese qualitative Untersuchung konzentriert sich auf die Daten (Tonaufnahme, die anhand eines Interviews während einer Sprechproduktionsübung im universitären Fremdsprachenunterricht gesammelt wurden. Um die emotionale Dimension der Lernenden während der Sprechproduktion zu identifizieren, wurden im Einzelinterview die Frage „Wie fühlst du dich während du eine Fremdsprache (Englisch sprichst?“ gestellt. Die Teilnehmer dieser Untersuchung waren 29 Studenten, die im WS 2016 - 2017 an Universität Nevşehir Hacı Bektaş Veli (Türkei immatrikuliert waren. Die Auswertung des Interviews folgte mit einer Transkription und einer Interpretation der Tonaufnahmen. Die Meinungen zu der emotionalen Dimension während der Sprechproduktion der Studenten wurden kategorisiert. Die Resultate dieser qualitativen Untersuchung zeigen, dass die emotionale Dimension der Lernenden im universitären Kontext sich in drei Kategorien (positiv, negativ und frühere Ausbildung verteilen.

Low-mass black holes as the remnants of primordial black hole formation.

Science.gov (United States)

Greene, Jenny E

2012-01-01

Bridging the gap between the approximately ten solar mass 'stellar mass' black holes and the 'supermassive' black holes of millions to billions of solar masses are the elusive 'intermediate-mass' black holes. Their discovery is key to understanding whether supermassive black holes can grow from stellar-mass black holes or whether a more exotic process accelerated their growth soon after the Big Bang. Currently, tentative evidence suggests that the progenitors of supermassive black holes were formed as ∼10(4)-10(5) M(⊙) black holes via the direct collapse of gas. Ongoing searches for intermediate-mass black holes at galaxy centres will help shed light on this formation mechanism.

Effects of local mass anomalies in Eoetvoes-like experiments

International Nuclear Information System (INIS)

Talmadge, C.; Aronson, S.H.; Fischbach, E.

1986-01-01

We consider in detail the effects of local mass anomalies in Eoetvoes-like experiments. It is shown that in the presence of an intermediate-range non-gravitational force, the dominant contributions to both the sign and magnitude of the Eoetvoes anomaly may come from nearby masses and not from the earth as a whole. This observation has important implications in the design and interpretation of future experiments, and in the formulation of unified theories incorporating new intermediate-range forces

The new intermediate long-bursting source XTE J1701-407

DEFF Research Database (Denmark)

Falanga, M.; Cumming, A.; Bozzo, E.

2009-01-01

functions with e-folding times of tau(1) = 40 +/- 3 s and tau(2) = 221 +/- 9 s. The bursts occurred at a persistent luminosity of L-per = 8.3 x 10(36) erg s(-1) (approximate to 2.2% of the Eddington luminosity). For the intermediate long-burst, the mass accretion rate per unit area onto the neutron star...

The IMS Software Integration Platform

Science.gov (United States)

1993-04-12

products to incorporate all data shared by the IMS applications. Some entities (time-series, images, a algorithm -specific parameters) must be managed...dbwhoanii, dbcancel Transaction Management: dbcommit, dbrollback Key Counter Assignment: dbgetcounter String Handling: cstr ~to~pad, pad-to- cstr Error...increment *value; String Maniputation: int cstr topad (array, string, arraylength) char *array, *string; int arrayjlength; int pad tocstr (string

Biomechanisch-kinemetrische Bewegungsanalyse und Ansätze zur Bewegungssteuerung für ein Training im Wellenreiten

OpenAIRE

Matschkur, Tina

2008-01-01

Neben der biomechanisch-kinemetrischen Bewegungsanalyse einzelner ausgewählter Techniken im Wellenreiten beschäftigt sich diese Dissertation auch ansatzweise im Rahmen einer elektromyographischen Fallstudie mit der muskulären Koordination bei der Bewegungsausführung im Surfen, um daraus Schlussfolgerungen für das Training im Wellenreiten treffen zu können. Ein geschichtlicher und wissenschaftlicher Überblick über das Wellenreiten leitet das Thema ein und macht somit auf die besondere Ausgangs...

Eisengehalt von Fleisch - Ermittlung des Eisengehalts im Fleisch verschiedener Tierarten

OpenAIRE

Westphal, Karsten; Klose, Ralf; Golze, Manfred

2009-01-01

Der Bericht beinhaltet Ergebnisse von Fleischuntersuchungen auf den Eisengehalt. Untersucht wurden 308 Schweinefleischproben und etwa 300 Fleischproben der Tierarten Rind, Bison, Auerochse, Büffel, Schaf, Ziege, Kaninchen, Wildschwein, Rehwild, Rotwild und Fasan. Die sächsischen Ergebnisse bestätigen Untersuchungen anderer Bundesländer und belegen den starken Rückgang des Eisengehaltes im Schweinefleisch. Er lag im Mittel bei 4,1 mg/kg Frischmasse (FM). Vor 30 Jahren lag der Eisengehalt...

Quad-Polarization Transmission for High-Capacity IM/DD Links

DEFF Research Database (Denmark)

Estaran Tolosa, Jose Manuel; Castaneda, Mario A. Usuga; Porto da Silva, Edson

2014-01-01

We report the first experimental demonstration of IM/DD links usi ng four states of polarization. Fiber - Induced polarization rotation is compensated with a simple tracking algorithm operating on the Stokes space. The principle is prove n at 128 Gb/s over 2 - km SSMF......We report the first experimental demonstration of IM/DD links usi ng four states of polarization. Fiber - Induced polarization rotation is compensated with a simple tracking algorithm operating on the Stokes space. The principle is prove n at 128 Gb/s over 2 - km SSMF...

Fission of intermediate mass nuclei by photons of stopping radiation in the maximum energy range 0,8 - 1,8 MeV

International Nuclear Information System (INIS)

Lima, D.A. de.

1983-07-01

The fission of intermediate mass nuclei in Al - Ta interval, induced by stopping radiation phtons of maximum energies between 0,8 and 1.8 GeV is studied. Nd and Sm thin targets and Al, Ti, Co, Zr, Nb, Ag, In and Ta thick targets were used, considering all peculiarities inherent to absorption of fission fragments in the target. The samples were exposed into the 2.5 GeV Electron Synchrotron in Bonn Univerity. The fission fragment tracks were registered in foil type detectors using mica muscovite for Sm and Nd, CR-39 for Al and Ti and makrofol for Co, Zr; Nb, Ag, In, Nd and Ta. The track length and track depth angle distributions were measured for determining fission efficiencies. The fission cross sections and nuclear fissionable of the studied elements were evaluated. (M.C.K.) [pt

The path of the Levantine intermediate water to the Alboran sea

Science.gov (United States)

Font, Jordi

1987-10-01

The Levantine Intermediate Water (LIW) traditionally has been assumed to reach the Alboran Sea as a counter-current along the North African coast. Here data are presented that confirm the LIW flow through the sill that separates the Balearic Islands from the mainland, after contouring cyclonically the western Mediterranean along the continental slope. This seems to be a seasonal phenomenon related to the process of deep water formation in the northwestern Mediterranean and to fluctuations in the Ligurian Current. In winter the LIW can circulate across the Catalan Sea without remarkable dilution, while in summer the intermediate outflow has almost lost the LIW water mass characteristics.

Female teams im eSport: Re-Konstruktion der Kategorie Geschlecht

OpenAIRE

Streubel, Anett

2010-01-01

"Das Ziel dieses Papers ist es, die Herausbildung von "female Teams" im eSport zu untersuchen. Das Hauptaugenmerk liegt hierbei auf Rekonstruktionsmechanismen der Kategorie Geschlecht, welche durch Sprache und Diskurse gebildet, erlernt und fortgeführt werden. Der Anteil der Spielerinnen, die das Computerspielen als Sport betreiben, wächst stetig an - deshalb soll in dieser Studie der Profibereich des eSport näher betrachtet werden. In einem Tätigkeitsfeld, in dem nicht der Körper im Mittelpu...

Zur mediopassiven 2. Und 3. Person dualis im indogermanischen

Directory of Open Access Journals (Sweden)

Bojan Čop

1972-12-01

Full Text Available Bekanntlich gibt es in einigen seltenen idg. Sprachen (im Arischen, Griechischen, Tocharischen auch Personal - suffixe für die 2. u n d 3. P. Du. des Mediopassivs. Von diesen sind die griechischen Ausgänge – 2. und 3. Du primär, 2. Du. sekundär, Du. sekundär sicher junge Neubildungen, s. z. B. Brugmann, Grdr.2 II 3 II, 657, § 602; Schwyzer, Gr. Gr. I 670, 672. Ein voll ausgebildetes System solcher Endungen besitzt das Arische; im Tocharischen kommt nur eine einzige Form mit solcher Endung vor, die die 2. P. Du. Med. lmperativi darstellt. Unter solchen Umständen scheint es schwierig, aus diesem Material wahrscheinliche Schlüsse für da_s Urindogermanische zu machen. Und doch ist gerade die tocharische Form, die uns eine ausserordentlich grosse Hilfe leistet, wenn man sie richtig zu beurteilen vermag. Die tocharische Endung, verbunden mit den arischen, wird unter Einschluss der allgemeinen Tendenzen und Regelungen im System der indogermanischen Personalsuffixe ohne Schwierigkeit die urindogermanische Urform erscheinen lassen.

[Glanz und Elend - Mythos und Wirklichkeit der Herrenhäuser im Baltikum] / Karsten Brüggemann

Index Scriptorium Estoniae

Brüggemann, Karsten, 1965-

2014-01-01

Arvustus: Glanz und Elend - Mythos und Wirklichkeit der Herrenhäuser im Baltikum. Hrsg. von Ilse von zur Mühlen im Auftrag der Carl-Schirren-Gesellschaft e.V. und des Ostpreußischen Landesmuseums Lüneburg. Kunstverlag Josef Fink. Lindenberg im Allgäu 2012

Season of infectious mononucleosis and risk of multiple sclerosis at different latitudes; the EnvIMS Study.

Science.gov (United States)

Lossius, Andreas; Riise, Trond; Pugliatti, Maura; Bjørnevik, Kjetil; Casetta, Ilaria; Drulovic, Jelena; Granieri, Enrico; Kampman, Margitta T; Landtblom, Anne-Marie; Lauer, Klaus; Magalhaes, Sandra; Myhr, Kjell-Morten; Pekmezovic, Tatjana; Wesnes, Kristin; Wolfson, Christina; Holmøy, Trygve

2014-05-01

Seasonal fluctuations in solar radiation and vitamin D levels could modulate the immune response against Epstein-Barr virus (EBV) infection and influence the subsequent risk of multiple sclerosis (MS). Altogether 1660 MS patients and 3050 controls from Norway and Italy participating in the multinational case-control study of Environmental Factors In Multiple Sclerosis (EnvIMS) reported season of past infectious mononucleosis (IM). IM was generally reported more frequently in Norway (p=0.002), but was associated with MS to a similar degree in Norway (odds ratio (OR) 2.12, 95% confidence interval (CI) 1.64-2.73) and Italy (OR 1.72, 95% CI 1.17-2.52). For all participants, there was a higher reported frequency of IM during spring compared to fall (p<0.0005). Stratified by season of IM, the ORs for MS were 1.58 in spring (95% CI 1.08-2.31), 2.26 in summer (95% CI 1.46-3.51), 2.86 in fall (95% CI 1.69-4.85) and 2.30 in winter (95% CI 1.45-3.66). IM is associated with MS independently of season, and the association is not stronger for IM during spring, when vitamin D levels reach nadir. The distribution of IM may point towards a correlation with solar radiation or other factors with a similar latitudinal and seasonal variation.

Hadron mass corrections in semi-inclusive deep inelastic scattering

International Nuclear Information System (INIS)

Accardi, A.; Hobbs, T.; Melnitchouk, W.

2009-01-01

We derive mass corrections for semi-inclusive deep inelastic scattering of leptons from nucleons using a collinear factorization framework which incorporates the initial state mass of the target nucleon and the final state mass of the produced hadron h. The hadron mass correction is made by introducing a generalized, finite-Q 2 scaling variable ζ h for the hadron fragmentation function, which approaches the usual energy fraction z h = E h /ν in the Bjorken limit. We systematically examine the kinematic dependencies of the mass corrections to semi-inclusive cross sections, and find that these are even larger than for inclusive structure functions. The hadron mass corrections compete with the experimental uncertainties at kinematics typical of current facilities, Q 2 2 and intermediate x B > 0.3, and will be important to efforts at extracting parton distributions from semi-inclusive processes at intermediate energies.

Abundances in Planetary Nebulae: an Autopsy of Low and Intermediate Mass Stars

Science.gov (United States)

Buell, James Francis

In this work we report on the results of synthetic thermally pulsing asymptotic giant branch models (TP-AGB) and compare the results to the abundance ratios in a sample of planetary nebulae. We use updated the input parameters for mass-loss, the stellar luminosity, and dredge-up. We calculated models with masses between 0.8 solar masses and 8 solar masses. We also calculated models with (Fe/H) between -2.5 and 0.3. The effect of the first, second, and third dredge-up as well as hot-bottom burning are reported on. The analysis of a sample of Galactic bulge and disk planetary nebulae is also reported on.

Testing the Paradigm that Ultraluminous X-Ray Sources as a Class Represent Accreting Intermediate-Mass Black Holes

Science.gov (United States)

Berghea, C. T.; Weaver, K. A.; Colbert, E. J. M.; Roberts, T. P.

2008-11-01

To test the idea that ultraluminous X-ray sources (ULXs) in external galaxies represent a class of accreting intermediate-mass black holes (IMBHs), we have undertaken a program to identify ULXs and a lower luminosity X-ray comparison sample with the highest quality data in the Chandra archive. We establish as a general property of ULXs that the most X-ray-luminous objects possess the flattest X-ray spectra (in the Chandra bandpass). No prior sample studies have established the general hardening of ULX spectra with luminosity. This hardening occurs at the highest luminosities (absorbed luminosity >=5 × 1039 erg s-1) and is in line with recent models arguing that ULXs are actually stellar mass black holes. From spectral modeling, we show that the evidence originally taken to mean that ULXs are IMBHs—i.e., the "simple IMBH model"—is nowhere near as compelling when a large sample of ULXs is looked at properly. During the last couple of years, XMM-Newton spectroscopy of ULXs has to a large extent begun to negate the simple IMBH model based on fewer objects. We confirm and expand these results, which validates the XMM-Newton work in a broader sense with independent X-ray data. We find that (1) cool-disk components are present with roughly equal probability and total flux fraction for any given ULX, regardless of luminosity, and (2) cool-disk components extend below the standard ULX luminosity cutoff of 1039 erg s-1, down to our sample limit of 1038.3 erg s-1. The fact that cool-disk components are not correlated with luminosity damages the argument that cool disks indicate IMBHs in ULXs, for which strong statistical support was never found.

Finanzmärkte – Unternehmungen – Informationen: Ergebnisse des Projektes im Wintersemester 2016/2017

OpenAIRE

Geyer, Helmut; Grau, Svenja; Giersch, Peter; Eckardt, Maximilian; Eder, Josephin; Catholy, Victoria; Pisak, Anastasia; Löser, Matthias; Jehring, Maximilian; Zhang, Haoyang; Grabengießer, Anja; Gruschwitz, Karoline; Heinrich, Katharina; Patzer, Vivien; Päsler, Florian

2018-01-01

Der vorliegende Beitrag der Wirtschaftswissenschaftlichen Schriften ist ein Sammelband, der die Beiträge der Studierenden des 2. Fachsemesters im Masterstudiengang General Management aus dem Wintersemester 2016/2017 umfasst. Die Einzelbeiträge wurden in einer zwei Monate dauernden Projektarbeit im Herbst 2016 erarbeitet und im Januar 2017 präsentiert. Der Themenschwerpunkt für dieses Jahr lag auf dem Bereich "Immobilien/Wohnungspolitik". Innerhalb dieser Vorgabe wurde ein breites Spektrum bea...

Coupling Front-End Separations, Ion Mobility Spectrometry, and Mass Spectrometry For Enhanced Multidimensional Biological and Environmental Analyses

Energy Technology Data Exchange (ETDEWEB)

Zheng, Xueyun; Wojcik, Roza; Zhang, Xing; Ibrahim, Yehia M.; Burnum-Johnson, Kristin E.; Orton, Daniel J.; Monroe, Matthew E.; Moore, Ronald J.; Smith, Richard D.; Baker, Erin M.

2017-06-12

Ion mobility spectrometry (IMS) is a widely used analytical technique for rapid molecular separations in the gas phase. IMS alone is useful, but its coupling with mass spectrometry (MS) and front-end separations has been extremely beneficial for increasing measurement sensitivity, peak capacity of complex mixtures, and the scope of molecular information in biological and environmental sample analyses. Multiple studies in disease screening and environmental evaluations have even shown these IMS-based multidimensional separations extract information not possible with each technique individually. This review highlights 3-dimensional separations using IMS-MS in conjunction with a range of front-end techniques, such as gas chromatography (GC), supercritical fluid chromatography (SFC), liquid chromatography (LC), solid phase extractions (SPE), capillary electrophoresis (CE), field asymmetric ion mobility spectrometry (FAIMS), and microfluidic devices. The origination, current state, various applications, and future capabilities for these multidimensional approaches are described to provide insight into the utility and potential of each technique.

An IMS testbed for SIP applications

DEFF Research Database (Denmark)

Caba, Cosmin Marius; Soler, José

2013-01-01

The paper presents the design and implementation of an emulation platform for the IP Multimedia Subsystem. The SIP Servlet API v1.1 has been used to implement the final system. The purpose of the emulation is to offer to IMS service developers an environment where they can integrate development...

Variable mycorrhizal benefits on the reproductive output of Geranium sylvaticum, with special emphasis on the intermediate phenotype.

Science.gov (United States)

Varga, S; Kytöviita, M-M

2014-03-01

In several gynodioecious species, intermediate sex between female and hermaphrodite has been reported, but few studies have investigated fitness parameters of this intermediate phenotype. Here, we examined the interactions between plant sex and arbuscular mycorrhizal (AM) fungal species affecting the reproductive output of Geranium sylvaticum, a sexually polymorphic plant species with frequent intermediate sexes between females and hermaphrodites, using a common garden experiment. Flowering phenology, AM colonisation levels and several plant vegetative and reproductive parameters, including seed and pollen production, were measured. Differences among sexes were detected in flowering, fruit set, pollen production and floral size. The two AM species used in the present work had different effects on plant fitness parameters. One AM species increased female fitness through increasing seed number and seed mass, while the other species reduced seed mass in all sexes investigated. AM fungi did not affect intermediate and hermaphrodite pollen content in anthers. The three sexes in G. sylvaticum did not differ in their reproductive output in terms of total seed production, but hermaphrodites had potentially larger fathering ability than intermediates due to higher anther number. The ultimate female function--seed production--did not differ among the sexes, but one of the AM fungi used potentially decreased host plant fitness. In addition, in the intermediate sex, mycorrhizal symbiosis functioned similarly in females as in hermaphrodites. © 2013 German Botanical Society and The Royal Botanical Society of the Netherlands.

Datengeleitetes Lernen im studienbegleitenden Deutschunterricht am Beispiel des KoGloss-Ansatzes

OpenAIRE

Dubova, Agnese; Proveja, Egita

2016-01-01

Der vorliegende Aufsatz stellt den sprachdidaktischen Ansatz KoGloss vor und beschreibt die Möglichkeiten seines Einsatzes im studienbegleitenden Deutschunterricht. Als eine der Formen des datengeleiteten Lernens ermöglicht der KoGloss-Ansatz eine forschungsorientierte und lernerzentrierte Herangehensweise, die insbesondere im akademischen Sprachunterricht gefragt ist. Eine korpusbasierte Erschließung von (Fach-)Wörtern und komplexen sprachlichen Mustern, das learning by doing, die Kooperatio...

Discovery of the weak neutral intermediate vector boson Zsup(O)

International Nuclear Information System (INIS)

Kiss, D.

1983-01-01

The experimental detection and identification of the theoretically predicted new particle, the neutral intermediate vector boson of weak and electromagnetic interactions are described. Some technical details of the experiment made by CERN group led by C. Rubbia are discussed. The mass and width of Zsup(O) particle are in agreement with theoretical predictions. The importance of the new discovery is emphasized. (D.Gy.)

IMS IN SMES - REASONS, ADVANTAGES AND BARRIERS ON IMPLEMENTATION

Directory of Open Access Journals (Sweden)

Dragan Rajković

2008-09-01

Full Text Available Appearance of a number of management systems with various and sometimes divergent demands, demands for revise of optimal strategy on implementation of these standards in small and medium-sized enterprises (SMEs and the attempt on their integration into integrated management system are suggested even more. Firstly question on choice and reasons for implementation of standards is raised. Management and employees expect benefits on the implementation and they pass and minimize the implementation barriers. Basic concept on integrated management system (IMS into SMEs and analyse on reasons, advantages and barriers at IMS implementation are presented in this paper.

Reconocimiento de imágenes utilizando redes neuronales artificiales

OpenAIRE

García García, Pedro Pablo

2013-01-01

Este trabajo describe el proceso de extracción de patrones característicos de imágenes,mediante la ayuda de Redes Neuronales Artificiales. La información de la Red Neuronal junto con datos adicionales de las imágenes, serán almacenados en una base de datos y consumidos por un servicio web. Un teléfono móvil con sistema operativo Android consumirá la información almacenada en el servicio web. Posteriormente al realizar una captura de imagen con la cámara del teléfono, este procesará la imag...

PROTOPLANETARY DISK MASSES FROM STARS TO BROWN DWARFS

International Nuclear Information System (INIS)

Mohanty, Subhanjoy; Mortlock, Daniel; Greaves, Jane; Pascucci, Ilaria; Apai, Daniel; Scholz, Aleks; Thompson, Mark; Lodato, Giuseppe; Looper, Dagny

2013-01-01

We present SCUBA-2 850 μm observations of seven very low mass stars (VLMS) and brown dwarfs (BDs). Three are in Taurus and four in the TW Hydrae Association (TWA), and all are classical T Tauri (cTT) analogs. We detect two of the three Taurus disks (one only marginally), but none of the TWA ones. For standard grains in cTT disks, our 3σ limits correspond to a dust mass of 1.2 M ⊕ in Taurus and a mere 0.2 M ⊕ in the TWA (3-10× deeper than previous work). We combine our data with other submillimeter/millimeter (sub-mm/mm) surveys of Taurus, ρ Oph, and the TWA to investigate the trends in disk mass and grain growth during the cTT phase. Assuming a gas-to-dust mass ratio of 100:1 and fiducial surface density and temperature profiles guided by current data, we find the following. (1) The minimum disk outer radius required to explain the upper envelope of sub-mm/mm fluxes is ∼100 AU for intermediate-mass stars, solar types, and VLMS, and ∼20 AU for BDs. (2) While the upper envelope of apparent disk masses increases with M * from BDs to VLMS to solar-type stars, no such increase is observed from solar-type to intermediate-mass stars. We propose this is due to enhanced photoevaporation around intermediate stellar masses. (3) Many of the disks around Taurus and ρ Oph intermediate-mass and solar-type stars evince an opacity index of β ∼ 0-1, indicating significant grain growth. Of the only four VLMS/BDs in these regions with multi-wavelength measurements, three are consistent with considerable grain growth, though optically thick disks are not ruled out. (4) For the TWA VLMS (TWA 30A and B), combining our 850 μm fluxes with the known accretion rates and ages suggests substantial grain growth by 10 Myr, comparable to that in the previously studied TWA cTTs Hen 3-600A and TW Hya. The degree of grain growth in the TWA BDs (2M1207A and SSPM1102) remains largely unknown. (5) A Bayesian analysis shows that the apparent disk-to-stellar mass ratio has a roughly

Separation and characterization of metallosupramolecular libraries by ion mobility mass spectrometry.

Science.gov (United States)

Li, Xiaopeng; Chan, Yi-Tsu; Casiano-Maldonado, Madalis; Yu, Jing; Carri, Gustavo A; Newkome, George R; Wesdemiotis, Chrys

2011-09-01

The self-assembly of Zn(II) ions and bis(terpyridine) (tpy) ligands carrying 120° or 180° angles between their metal binding sites was utilized to prepare metallosupramolecular libraries with the connectivity. These combinatorial libraries were separated and characterized by ion mobility mass spectrometry (IM MS) and tandem mass spectrometry (MS(2)). The 180°-angle building blocks generate exclusively linear complexes, which were used as standards to determine the architectures of the assemblies resulting from the 120°-angle ligands. The latter ligand geometry promotes the formation of macrocyclic hexamers, but other n-mers with smaller (n = 5) or larger ring sizes (n = 7-9) were identified as minor products, indicating that the angles in the bis(terpyridine) ligand and within the coordinative tpy-Zn(II)-tpy bonds are not as rigid, as previously believed. Macrocyclic and linear isomers were detected in penta- and heptameric assemblies; in the larger octa- and nonameric assemblies, ring-opened conformers with compact and folded geometries were observed in addition to linear extended and cyclic architectures. IM MS(2) experiments provided strong evidence that the macrocycles present in the libraries were already formed in solution, during the self-assembly process, not by dissociation of larger complexes in the gas phase. The IM MS/MS(2) methods provide a means to analyze, based on size and shape (architecture), supramolecular libraries that are not amenable to liquid chromatography, LC-MS, NMR, and/or X-ray techniques.

Connecting imaging mass spectrometry and magnetic resonance imaging-based anatomical atlases for automated anatomical interpretation and differential analysis.

Science.gov (United States)

Verbeeck, Nico; Spraggins, Jeffrey M; Murphy, Monika J M; Wang, Hui-Dong; Deutch, Ariel Y; Caprioli, Richard M; Van de Plas, Raf

2017-07-01

Imaging mass spectrometry (IMS) is a molecular imaging technology that can measure thousands of biomolecules concurrently without prior tagging, making it particularly suitable for exploratory research. However, the data size and dimensionality often makes thorough extraction of relevant information impractical. To help guide and accelerate IMS data analysis, we recently developed a framework that integrates IMS measurements with anatomical atlases, opening up opportunities for anatomy-driven exploration of IMS data. One example is the automated anatomical interpretation of ion images, where empirically measured ion distributions are automatically decomposed into their underlying anatomical structures. While offering significant potential, IMS-atlas integration has thus far been restricted to the Allen Mouse Brain Atlas (AMBA) and mouse brain samples. Here, we expand the applicability of this framework by extending towards new animal species and a new set of anatomical atlases retrieved from the Scalable Brain Atlas (SBA). Furthermore, as many SBA atlases are based on magnetic resonance imaging (MRI) data, a new registration pipeline was developed that enables direct non-rigid IMS-to-MRI registration. These developments are demonstrated on protein-focused FTICR IMS measurements from coronal brain sections of a Parkinson's disease (PD) rat model. The measurements are integrated with an MRI-based rat brain atlas from the SBA. The new rat-focused IMS-atlas integration is used to perform automated anatomical interpretation and to find differential ions between healthy and diseased tissue. IMS-atlas integration can serve as an important accelerator in IMS data exploration, and with these new developments it can now be applied to a wider variety of animal species and modalities. This article is part of a Special Issue entitled: MALDI Imaging, edited by Dr. Corinna Henkel and Prof. Peter Hoffmann. Copyright © 2017. Published by Elsevier B.V.

Removal of anthracene and phenanthrene by filamentous fungi capable of cortexolone 11-hydroxylation.

Science.gov (United States)

Lisowska, K; Długoński, J

1999-01-01

Nine fungal strains showing ability of cortexolone hydroxylation to epicortisol and/or cortisol were screened in this work for anthracene and phenanthrene elimination (250 mg/l). All of the strains (Cylindrocladium simplex IM 2358, C. simplex IM 2358/650, Monosporium olivaceum IM 484, Curvularia lunata IM 2901, C. lunata IM 2901/366, C. tuberculata IM 4417, Cunninghamella elegans IM 1785, C. elegans IM 1785/21Gp, C. elegans IM 1785/10Gi) significantly removed anthracene and phenanthrene. During incubation with anthracene formation of intermediate products was observed. The amount of the main intermediate product, identified as 9, 10-anthraquinone, was not greater than 22.2% of the anthracene introduced to the fungal cultures. C. elegans IM 1785/21Gp was the best degrader of both anthracene and phenanthrene, removing 81.6 and 99.4% of these compounds after 7 days, respectively. Phenanthrene removal by C. elegans IM 1785/21Gp was preceded by PAHs accumulation in mycelium and growth inhibition. Elimination of phenanthrene started after one day of incubation and was related to the fungus growth.

Spontane Mobilisierung und der Wandel kollektiver Formationen im Internet. Eine Fallstudie zur PEGIDA-Bewegung

Directory of Open Access Journals (Sweden)

Sang-hui Nam

2016-11-01

Full Text Available Der vorliegende Beitrag beschäftigt sich mit der Frage, wie sich eine aus spontaner Mobilisierung entstandene soziale Bewegung als kollektive Formation im Internet entwickelt. Da spontane Bewegungen in aller Regel nur über eine schwache kollektive Identität verfügen, werden sie bislang überwiegend als Übergangsphänomen betrachtet. Viele Studien beschäftigten sich eher mit den Folgen spontaner Mobilisierung, insbesondere der Frage, wie daraus eine nachhaltige Bewegung entstehen kann. Die kollektive Formation selbst ist bis dato weitgehend eine Blackbox geblieben. In der vorliegenden Studie widme ich mich folgenden zentralen Forschungsfragen: 1. Wie werden kollektive Formationen aus spontanen ProtestteilnehmerInnen dargestellt und generiert? 2. Wie ändern sich diese im Verlauf der Mobilisierung? Im Mittelpunkt der empirischen Analyse stehen Online-Kommentare, die eine zunehmend wichtige Rolle für soziale Bewegungen und spontane Mobilisierungsprozesse spielen. Am Beispiel von PEGIDA wird die Konstruktion einer kollektiven Formation über Live-Kommentare zu Live-Übertragungen von PEGIDA-Demonstrationen sowie deren Wandel in drei Phasen untersucht. Im ersten Schritt werden die soziotechnischen Grundlagen kollektiven Handelns im Internet erläutert. Der zweite Schritt befasst sich mit der methodischen Vorgehensweise. Im dritten Schritt werden ausgewählte Textpassagen von Online-Kommentaren analysiert. Anschließend wird der Wandel kollektiver Formationen nachgezeichnet. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs170138

Professionalisierung und Doping im Sport

OpenAIRE

Wüterich, Christoph

2004-01-01

Der Beitrag untersucht Zusammenhänge zwischen der zunehmenden Professionalisierung des Sports und dem Anstieg von Dopingvergehen. Er zeigt, dass im historischen Vergleich beide Phänomene nicht neu sind, dass sich die Probleme aufgrund der steigenden Bedeutung des Leistungssports aber zugespitzt haben. Ausgehend von einer juristischen und sozioökonomischen Analyse der Anreize zu Doping werden Lösungsvorschläge entwickelt. The author analyzes the interdependencies between a growing commercia...

Editorial: Partizipationschancen im Kulturraum Internet nutzen und gestalten: Das Beispiel Web 2.0

Directory of Open Access Journals (Sweden)

Kerstin Mayrberger

2011-10-01

öffentlichkeit aufzubauen. Auch im formalem Bildungsbereich steckt das partizipative Lehren und Lernen unter adaptierten Bedingungen des Web 2.0 noch in den Anfängen. Zudem zeigen empirische Untersuchungen, dass Anwendungen des Web 2.0 wie Social Software gerade von der heranwachsenden Generation erst zögerlich und teilweise gar rückläufig für die Artikulation eigener Interessen eingesetzt werden (mpfs 2011, 2010; van Eimeren und Frees 2010. Die These von einer «Netzgeneration», die das Web 2.0 auf eine souveräne Art und Weise benutzt und die sich bietenden Partizipationschancen ausnutzt, um eigene Interessen zu artikulieren, liess sich bisher nicht bestätigen. Deshalb gilt es heute interdisziplinär zu untersuchen, welche Partizipationschancen das Internet zur Zeit tatsächlich eröffnet. Aus medienpädagogischer Sicht stellen sich besonders Fragen nach dem spezifischen Partizipationspotenzial des Internets für unterschiedliche Zielgruppen wie Kinder, Jugendliche, Erwachsene oder Senioren und in welchen informellen und formalen Bildungskontexten eine Beteiligung in welchem Masse ermöglicht wird bzw. ermöglicht werden kann. Dabei sind auch die Motive für die Nutzung, vor allem aber Nicht-Nutzung von eingeräumten Beteiligungsmöglichkeiten in bildungsbezogenen Kontexten von Interesse. Die vorliegende Ausgabe der Online-Zeitschrift «MedienPädagogik» trägt zur Diskussion dieser Fragen bei. Sieben Beiträge setzen sich aus spezifischen Perspektiven in Form empirischer Analysen und konzeptioneller Überlegungen mit den Partizipationschancen im Internet auseinander. Dabei lassen sich zwei vorherrschende Zugänge auf Partizipation im Netz ausmachen: Einerseits eine Perspektive im Feld der politischen Beteiligung und Bildung und andererseits eine Perspektive auf Lehren und Lernen im Web 2.0. Bei den ersten vier Beiträgen handelt es sich um Publikationen, die auf Vorträgen basieren, die im Rahmen des Symposiums «Partizipationschancen im Kulturraum Internet – am Beispiel des

bildbild – visuelle Kompetenz im Unterricht

Directory of Open Access Journals (Sweden)

Norbert Grube

2013-05-01

Full Text Available Der vorliegende Artikel stellt das Webseiten-Projekt bildbild vor. Der Webseite liegt die Motivation zugrunde, Schülerinnen und Schüler für ein Nachdenken über globale Themen zu sensibilisieren. Ein solches Nachdenken ist immer auch eines über bildlich vermittelte Wirklichkeit. Es ist mit bildbild ein Anliegen, angesichts einer allseits konstatierten «Bilderflut» ein didaktisches Medium zu entwickeln, das einen Fundus an historischen und aktuellen Fotografien zur Verfügung stellt und diese so aufbereitet, dass sie gerade nicht hinter ihrer illustrativen Funktion verschwinden. Dadurch sollen die Bilder für ein selbständiges Lernen auf dem Weg hin zu einer visuellen Kompetenz einsetzbar gemacht werden. Der Beitrag beleuchtet die Entwicklung der Webseite vor dem Hintergrund kulturkritischer Haltungen zum Bild seit der Moderne sowie im Rahmen dessen, was seit den 1970er Jahren im pädagogischen Kontext als Visual Literacy diskutiert und gefördert wird. Dabei wird auch auf die medialen Potenziale einer Webseite für die Bildlesekompetenz von Jugendlichen eingegangen.

A plan for location calibration of IMS stations and near Kazakhstan

International Nuclear Information System (INIS)

Richards, P.G.; Kim, W.-Yo.; Khalturin, V.I.

2001-01-01

For purposes of monitoring compliance with the Comprehensive Nuclear Test-Ban Treaty, it is desirable to be able to locate seismic events routinely to within an uncertainty not greater than 1000 square km. From more than five years of experience with publication of the Reviewed Event Bulletin (REB) by the Prototype International Data Centre (PIDC), resulting in estimated locations for more than 100,000 seismic events, it is apparent that improved location accuracy is needed in order to reduce uncertainties below 1000 square km. In this paper, we outline a three-year program of applied research which commenced in March 2000 and which has the goal of achieving improved REB locations based upon data to be contributed to the International Data Centre from 30 IMS stations in Eastern Asia. Our first efforts will focus on the four IMS seismographic stations in Kazakhstan (AKT, BRV, KUR, MAK), together with IMS stations ZAL in Russia and AAK in Kyrgyzstan. Following the recommendations of two 'IMS Location Calibration Workshops' held in Oslo, Norway, in 1999 and 2000, our approach is to generate station-specific travel times for each observable seismic phase, as a function of distance and azimuth (and depth, where possible). Such travel times are obtained on the basis of (i) early studies based mainly on earthquake data (e.g. Nersesov and Rautian, 1964), (ii) Deep Seismic Sounding, and (iii) recent studies of nuclear and chemical explosions. We are also using (iv) an empirical approach in which phases are picked at IMS stations, for so-called Ground Truth events whose location is known quite accurately on the basis of additional data, obtained for example from local and regional networks. (author)

Intermediate neutron spectrum problems and the intermediate neutron spectrum experiment

International Nuclear Information System (INIS)

Jaegers, P.J.; Sanchez, R.G.

1996-01-01

Criticality benchmark data for intermediate energy spectrum systems does not exist. These systems are dominated by scattering and fission events induced by neutrons with energies between 1 eV and 1 MeV. Nuclear data uncertainties have been reported for such systems which can not be resolved without benchmark critical experiments. Intermediate energy spectrum systems have been proposed for the geological disposition of surplus fissile materials. Without the proper benchmarking of the nuclear data in the intermediate energy spectrum, adequate criticality safety margins can not be guaranteed. The Zeus critical experiment now under construction will provide this necessary benchmark data

Two-loop renormalization group analysis of supersymmetric SO(10) models with an intermediate scale

International Nuclear Information System (INIS)

Bastero-Gil, M.; Brahmachari, B.

1996-03-01

Two-loop evolutions of the gauge couplings in a class of intermediate scale supersymmetric SO(10) models including the effect of third generation Yukawa couplings are studied. The unification scale, the intermediate scale and the value of the unification gauge coupling in these models are calculated and the gauge boson mediated proton decay rates are estimated. In some cases the predicted proton lifetime turns out to be in the border-line of experimental limit. The predictions of the top quark mass, the mass ratio m b (m b )/m τ (m τ ) from the two-loop evolution of Yukawa couplings and the mass of the left handed neutrino via see-saw mechanism are summarized. The lower bounds on the ratio of the VEVs of the two low energy doublets (tan β) from the requirement of the perturbative unitarity of the top quark Yukawa coupling up to the grand unification scale are also presented. All the predictions have been compared with those of the one-step unified theory. (author). 33 refs, 5 figs, 1 tab

Characterization of intermediate products of solar photocatalytic degradation of ranitidine at pilot-scale.

Science.gov (United States)

Radjenović, Jelena; Sirtori, Carla; Petrović, Mira; Barceló, Damià; Malato, Sixto

2010-04-01

In the present study the mechanisms of solar photodegradation of H(2)-receptor antagonist ranitidine (RNTD) were studied in a well-defined system of a pilot plant scale Compound Parabolic Collector (CPC) reactor. Two types of heterogeneous photocatalytic experiments were performed: catalysed by titanium-dioxide (TiO(2)) semiconductor and by Fenton reagent (Fe(2+)/H(2)O(2)), each one with distilled water and synthetic wastewater effluent matrix. Complete disappearance of the parent compounds and discreet mineralization were attained in all experiments. Furthermore, kinetic parameters, main intermediate products, release of heteroatoms and formation of carboxylic acids are discussed. The main intermediate products of photocatalytic degradation of RNTD have been structurally elucidated by tandem mass spectrometry (MS(2)) experiments performed at quadrupole-time of flight (QqToF) mass analyzer coupled to ultra-performance liquid chromatograph (UPLC). RNTD displayed high reactivity towards OH radicals, although a product of conduction band electrons reduction was also present in the experiment with TiO(2). In the absence of standards, quantification of intermediates was not possible and only qualitative profiles of their evolution could be determined. The proposed TiO(2) and photo-Fenton degradation routes of RNTD are reported for the first time. (c) 2010 Elsevier Ltd. All rights reserved.

IMS Learning Design: De stand van zaken

NARCIS (Netherlands)

Tattersall, Colin; Manderveld, Jocelyn

2005-01-01

Tattersall, C. & Manderveld, J. (2004) IMS Learning Design: De stand van zaken In: Gorissen, P., Manderveld, J., Benneker, F. & Cordewener, B. Leertechnologie in de Lage Landen (pp. 31-33). Utrecht, Stichting Surf. Ook beschikbaar in dspace: http://hdl.handle.net/1820/270

[Christofer Herrmann. Kloster und Burg - die architektur des Deutschens Ordens im Pressen und Livland. In : Glaube, Macht und Pracht. GeistlicheGemeinschaften des Ostseeraums im Zeitalter der Backsteingotik] / Dennis Hortmuth

Index Scriptorium Estoniae

Hortmuth, Dennis

2011-01-01

Arvustus: Christofer Herrmann. Kloster und Burg - die Architektur des Deutschen Ordens in Preussen und Livland. In : Glaube, Macht und Pracht. GeistlicheGemeinschaften des Ostseeraums im Zeitalter der Backsteingotik (=Archäologie und Geschichte im Ostseeraum; Archaeology and History of the Baltic 6) Rahden : Verlag Marie Leidorf, 2009. S. 209-219. Saksa Ordu arhitektuurist Preisi- ja Liivimaal

Evaluation of the Indian Migration Study Physical Activity Questionnaire (IMS-PAQ): a cross-sectional study.

Science.gov (United States)

Sullivan, Ruth; Kinra, Sanjay; Ekelund, Ulf; Bharathi, A V; Vaz, Mario; Kurpad, Anura; Collier, Tim; Reddy, K Srinath; Prabhakaran, Dorairaj; Ebrahim, Shah; Kuper, Hannah

2012-02-09

Socio-cultural differences for country-specific activities are rarely addressed in physical activity questionnaires. We examined the reliability and validity of the Indian Migration Study Physical Activity Questionnaire (IMS-PAQ) in urban and rural groups in India. A sub-sample of IMS participants (n = 479) was used to examine short term (≤ 1 month [n = 158]) and long term (> 1 month [n = 321]) IMS-PAQ reliability for levels of total, sedentary, light and moderate/vigorous activity (MVPA) intensity using intraclass correlation (ICC) and kappa coefficients (k). Criterion validity (n = 157) was examined by comparing the IMS-PAQ to a uniaxial accelerometer (ACC) worn ≥ 4 days, via Spearman's rank correlations (ρ) and k, using Bland-Altman plots to check for systematic bias. Construct validity (n = 7,000) was established using linear regression, comparing IMS-PAQ against theoretical constructs associated with physical activity (PA): BMI [kg/m2], percent body fat and pulse rate. IMS-PAQ reliability ranged from ICC 0.42-0.88 and k = 0.37-0.61 (≤ 1 month) and ICC 0.26 to 0.62; kappa 0.17 to 0.45 (> 1 month). Criterion validity was ρ = 0.18-0.48; k = 0.08-0.34. Light activity was underestimated and MVPA consistently and substantially overestimated for the IMS-PAQ vs. the accelerometer. Criterion validity was moderate for total activity and MVPA. Reliability and validity were comparable for urban and rural participants but lower in women than men. Increasing time spent in total activity or MVPA, and decreasing time in sedentary activity were associated with decreasing BMI, percent body fat and pulse rate, thereby demonstrating construct validity. IMS-PAQ reliability and validity is similar to comparable self-reported instruments. It is an appropriate tool for ranking PA of individuals in India. Some refinements may be required for sedentary populations and women in India.

Interaction of the Faroe Bank Channel overflow with Iceland Basin intermediate waters

Science.gov (United States)

Ullgren, Jenny E.; Fer, Ilker; Darelius, Elin; Beaird, Nicholas

2014-01-01

The narrow and deep Faroe Bank Channel (FBC) is an important pathway for cold, dense waters from the Nordic Seas to flow across the Iceland-Scotland ridge into the North Atlantic. The swift, turbulent FBC overflow is associated with strong vertical mixing. Hydrographic profiles from a shipboard survey and two Slocum electric gliders deployed during a cruise in May-June 2012 show an intermediate water mass characterized by low salinity and low oxygen concentration between the upper waters of Atlantic origin and the dense overflow water. A weak low-salinity signal originating north-east of Iceland is discernible at the exit of the FBC, but smeared out by intense mixing. Further west (downstream) marked salinity and oxygen minima are found, which we hypothesize are indicators of a mixture of Labrador Sea Water and Intermediate Water from the Iceland Basin. Water mass characteristics vary strongly on short time scales. Low-salinity, low-oxygen water in the stratified interface above the overflow plume is shown to move along isopycnals toward the Iceland-Faroe Front as a result of eddy stirring and a secondary, transverse circulation in the plume interface. The interaction of low-salinity, low-oxygen intermediate waters with the overflow plume already at a short distance downstream of the sill, here reported for the first time, affects the final properties of the overflow waters through entrainment and mixing.

MIP-based enhanced mid-session macro-mobility for IMS-controlled state-full applications

DEFF Research Database (Denmark)

Renier, Thibault Julien; Fathi, Hanane; Schwefel, Hans-Peter

2007-01-01

, e.g., block unauthorized visiting users. The 3GPP IP Multimedia Subsystem (IMS) is a platform standardized towards network-independent access and session control. The current IMS specifications do not allow for any change of the user's current IP address during an ongoing session, which prevents...

Pragmatic awareness of Suggestions: From (Im)Polite Mannerism to Attitudinal Appropriateness

OpenAIRE

Hamid Allami; Nasim Boustani

2017-01-01

The present research seeks to determine: (a) Iranian EFL learners’ application of suggestion semantic formulae ;(b) their attitude of appropriateness in terms of confidence in the employment of appropriate supportive moves; (c), their (im)polite mannerism with respect to the selected strategies; and (d) the relationship between attitude of appropriateness and mannerism of (im)politeness. An Oxford Quick placement Test (OQPT) was administered among 60 Iranian EFL learners to check their langua...

Produkteinführung im Umfeld des Niedergangs: Die Blu-ray Disk

OpenAIRE

Oestreicher, Klaus; Walton, Nigel; Newnham, M.

2014-01-01

Dieses Kapitel diskutiert die Problematik existenzieller Bedrohung durch radikale Innovationen. Virtuelle Marktangebote verändern Märkte im Home Entertainment und das Konsumverhalten grund¬legend. Zunehmend gefährden dematerialisierte Produkte, welche zu Services werden und Folge der Information Communication Tech¬nologies (ICT) sind, die Lebensfähigkeit physischer Produkte. Deren Märkte sind im Niedergang und das bedroht nicht nur die Hersteller optischer Disks (CD und DVD), sondern beeinflu...

Soft electromagnetic bremsstrahlung in inelastic hadronic collisions at high and intermediate energies

International Nuclear Information System (INIS)

Rueckl, R.

1978-01-01

Electromagnetic bremsstrahlung in hadronic collisions was studied extensively at low and intermediate energies. It was found that the infrared divergent term of the cross section describes the data well up to surprisingly large photon energies. Using essentially the same soft photon approximation, production of low mass-low energy electron pairs via internal conversion of soft virtual bremsstrahlung accompanying the production of charged hadrons in hadron-hadron collisions at very high and intermediate energies. The resulting electron yields explain, at least in part, the direct electrons with small transverse momenta seen at the ISR, and are in no contradiction to the rates observed at LAMPF

Facebook Ethnography: The Poststructural Ontology of Transnational (Im Migration Research

Directory of Open Access Journals (Sweden)

David Joseph Piacenti PhD

2014-02-01

Full Text Available This theoretical article discusses the creative utility of Facebook as a new ethnographic tool in which to study transnational (im migration. Facebook ethnography allows the (im migration researcher to transcend the four structural dualities that constrain transnational ethnographic research: (a geographic constraints, (b travel funding constraints, (c travel time constraints, and (d the logistical constraints of entrée into new ethnographic contexts. Facebook ethnography also allows the qualitative researcher to temporarily transcend the ontological structuralist dualities of traditional research methods, producing a new poststructural epistemological and ontological methodology.

A flicker noise/IM3 cancellation technique for active mixer using negative impedance

NARCIS (Netherlands)

Cheng, W.; Annema, Anne J.; Wienk, Gerhardus J.M.; Nauta, Bram

2013-01-01

Abstract—This paper presents an approach to simultaneously cancel flicker noise and IM3 in Gilbert-type mixers, utilizing negative impedances. For proof of concept, two prototype double-balanced mixers in 0.16- m CMOS are fabricated. The first demonstration mixer chip was optimized for full IM3

78 FR 79498 - Notice Pursuant to The National Cooperative Research and Production Act of 1993-IMS Global...

Science.gov (United States)

2013-12-30

... Production Act of 1993--IMS Global Learning Consortium, Inc. Notice is hereby given that, on November 22....C. Sec. 4301 et seq. (``the Act''), IMS Global Learning Consortium, Inc. (``IMS Global'') has filed..., Carson-Dellosa Publishing, Greensboro, NC; Data Recognition Group, Maple Grove, MN; Nelson Education Ltd...

78 FR 7456 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-IMS Global...

Science.gov (United States)

2013-02-01

... District, Selbyville, DE; learning.com , Portland, OR; State of Michigan Dept. of Education, Bureau of... Production Act of 1993--IMS Global Learning Consortium, Inc. Notice is hereby given that, on December 28....C. 4301 et seq. (``the Act''), IMS Global Learning Consortium, Inc. (``IMS Global'') has filed...

Intermediate and deep water mass distribution in the Pacific during the Last Glacial Maximum inferred from oxygen and carbon stable isotopes

Science.gov (United States)

Herguera, J. C.; Herbert, T.; Kashgarian, M.; Charles, C.

2010-05-01

Intermediate ocean circulation changes during the last Glacial Maximum (LGM) in the North Pacific have been linked with Northern Hemisphere climate through air-sea interactions, although the extent and the source of the variability of the processes forcing these changes are still not well resolved. The ventilated volumes and ages in the upper wind driven layer are related to the wind stress curl and surface buoyancy fluxes at mid to high latitudes in the North Pacific. In contrast, the deeper thermohaline layers are more effectively ventilated by direct atmosphere-sea exchange during convective formation of Subantarctic Mode Waters (SAMW) and Antarctic Intermediate Waters (AAIW) in the Southern Ocean, the precursors of Pacific Intermediate Waters (PIW) in the North Pacific. Results reported here show a fundamental change in the carbon isotopic gradient between intermediate and deep waters during the LGM in the eastern North Pacific indicating a deepening of nutrient and carbon rich waters. These observations suggest changes in the source and nature of intermediate waters of Southern Ocean origin that feed PIW and enhanced ventilation processes in the North Pacific, further affecting paleoproductivity and export patters in this basin. Furthermore, oxygen isotopic results indicate these changes may have been accomplished in part by changes in circulation affecting the intermediate depths during the LGM.

SISTEMAS MULTIMEDIA BASADOS EN PROTOCOLO IP IMS APLICADOS A SERVICIOS LTE DE 4G

Directory of Open Access Journals (Sweden)

Edgar Alfonso Cipagauta Pedraza

2013-01-01

Full Text Available Este artículo presenta de una manera sencilla, el sistema creado para soportar los servicios de multimedia dentro de red de nueva generación (NGN llamada IP Multimedia Subsystem (IMS a la vez que se explica su relación con la tecnología Long Term Evolution (LTE definida por el 3GPP en su release 8. IMS se trata de una arquitectura integrada en el núcleo de red para ofrecer servicios multimediales de audio y video sobre una infraestructura. Entonces ahora, los servicios prestados pasarán a ser ofrecidos a través de IP IMS y será la piedra angular en donde estos servicios se generarán y se ofrecerán. LTE es sin duda un impulsor de IMS, pero hay otros factores que empiezan a favorecer y a plantear un modelo de negocio favorable para la arquitectura multimedia. IMS está orientado a habilitar la convergencia de servicios, combinando el crecimiento de la Internet con el de las comunicaciones móviles, desde cualquier ubicación y método de forma continua y permanente.

Discovery and Rossiter-McLauglin effect of exoplanet kepler-8b

DEFF Research Database (Denmark)

Jenkins...[], Jon M.; Borucki, W.J.; Koch, D. G.

2010-01-01

We report on the discovery and the Rossiter-McLaughlin (R-M) effect of Kepler-8b, a transiting planet identified by the NASA Kepler Mission. Kepler photometry and Keck-HIRES radial velocities yield the radius and mass of the planet around this F8IV subgiant host star. The planet has a radius R P...

EXTREMISMUS IM KLASSENZIMMER - THEORETISCHE CHANCEN UND MÖGLICHKEITEN DES POLITIKUNTERRICHTES.

Directory of Open Access Journals (Sweden)

Amelie Zuschke

2015-06-01

Full Text Available Durch Phänomene wie PEGIDA wird eine Unsicherheit in der Bevölkerung ausgedrückt, die auch vor den Schultüren nicht Halt macht. Ein Querschnitt der Gesellschaft sitzt im Klassenraum und auf diesen muss sich eingestellt werden. Ob Kinder zuhause oder in ihrer Freizeit mit Populismus konfrontiert werden, die Schule hat als immer größerer Teil im Leben von Schülern in Deutschland (im Zuge der nach und nach fortschreitenden Einführung eines Ganztages-Prinzips auch eine Verantwortung mit diesen Eindrücken und Einflüssen bedacht umzugehen. Deutschland sollte aus der eigenen Geschichte heraus zudem die aufmerksame und sensible Handhabung mit extremem Gedankengut im Allgemeinen und mit rechtsextremistischem Gedankengut im Besonderen haben. Die Tendenz zu den politischen Extremen in wirtschaftlich und sozial herausfordernden Zeiten ist ein mit jedem wirtschaftlichen Abschwung auftretendes Phänomen, aber stark nationalistisches Gedankengut ist mit der heutigen Idealvorstellung von einem offenen Europa nicht vereinbar. In der Bundesrepublik Deutschland fußt die politische Bildung, geschichtlich begründet, auf demokratievermittelnden Prinzipien. Diese eignen sich vielseitig für die Auseinandersetzung mit Extremismus und den hierzu unumstrittenen Grundlagen und Werte der pluralistischen Gesellschaft in einer Demokratie. Das Kontroversitätsgebot des Beutelsbacher Konsenses aus dem Jahr 1977 (vgl Breit/Massig, 1993 bietet einen Ansatz zur Behandlung von Extremismus in der politischen Bildung auf der Grundlage der gegenseitigen Akzeptanz. Hier wird das Kontroversitätsgebot aufgeschlüsselt und anschließend auf Extremismus in der Schule bezogen. Die Fragestellung, wie der Politikunterricht trotz des Kontroversitätsgebotes mit Extremismus umgehen sollte, ist auf den Umgang mit dem gegenwärtigen Rechtsextremismus ausgelegt, welcher einen großen Teil politisch motivierter Straftaten begründet, sich in radikalisierter Form am stärksten gegen

Entwicklung der Reglementierung von 10 MEM-Berufen im Kontext von Bildungsreformen und dem Wandel in der Arbeitswelt: Eine Kurzstudie im Auftrag von LIBS: Eine Kurzstudie im Auftrag von LIBS Industrielle Berufslehren Schweiz, Baden

OpenAIRE

Egg, Maria Esther; Renold, Ursula

2015-01-01

Im Auftrag der LIBS Industrielle Berufslehren Schweiz, hat die KOF die Entwicklung von 10 MEM1-Berufsbildern seit dem ersten Berufsbildungsgesetz dargestellt und diese eingebettet in eine kurze Zusammenfassung der wichtigsten Etappenschritte des Schweizer Berufsbildungssystems.

IMS Learning Design desde dentro. Una especificación para crear escenarios de aprendizaje online (parte I)

NARCIS (Netherlands)

Burgos, Daniel; Berbegal, Nidia; Griffiths, David; Tattersall, Colin; Koper, Rob

2005-01-01

IMS Learning Design, IMS LD de ahora en adelante (IMS, 2003), es una especificación centrada en formación online o e-learning y que permite modelar programaciones curriculares o lecciones presenciales de forma que puedan ser seguidas online, construyendo lo que se denomina Unidades de Aprendizaje

Aplicativo Web para la Fusión de Imágenes Satelitales

Directory of Open Access Journals (Sweden)

Javier Medina

2013-06-01

Full Text Available En este artículo se implementa un servicio en la Web que ofrece la posibilidad de realizar la fusión de imágenes de satélite. A lo largo del artículo tres temáticas importantes son abordadas. La primera temática corresponde al servicio Web, éste servicio es implementado usando software libre, donde el usuario puede realizar una solicitud del servicio de fusión. La segunda temática se ocupa del análisis de la transformada rápida de Wavelet haar (TRWH. La última temática detalla la metodología, para realizar la fusión de imágenes usando la TRWH. Con el fin de determinar la eficiencia de la TRWH, cinco Wavelets diferentes fueron implementadas para fusionar el mismo par de imágenes satelitales. Las imágenes resultantes fueron evaluadas tanto en la calidad espacial como espectral a través de cuatro índices. Los mejores resultados de la evaluación fueron obtenidos con la TRWH la cual preserva la riqueza espectral y mejora su calidad espacial

Original models of NGN/IMS-networks surrounded by circuit-switched systems

OpenAIRE

Kulikov, Nikolay

2014-01-01

On obtaining of the Alexander Graham Bell a patent for invention of the telephone in 1987, the communication system consistently has gone through several evolutionary stages: from analog lines and manual switches to video telephony and IMS architecture. Each of the stages can be described by specific switching systems, data transmission systems and types of transmitted information. After implementation of such solution, it is possible to create a number of access nodes in the Operators IMS-ne...

Influence of the coupling between an atmospheric pressure ion mobility spectrometer and the low pressure ion inlet of a mass spectrometer on the mobility measurement

Directory of Open Access Journals (Sweden)

Gunzer Frank

2016-01-01

Full Text Available Ion mobility spectrometers (IMS are versatile gas analyzers. Due to their small size and robustness, combined with a very high sensitivity, they are often used in gas sensing applications such as environmental monitoring. In order to improve the selectivity, they are typically combined with a mass spectrometer (MS. Since IMS works at atmospheric pressure, and MS works at vacuum, a special interface reducing the pressure over normally two stages has to be used. In this paper the influence of this coupling of different pressure areas on the IMS signal will be analyzed with help of finite elements method simulations.

An IMS Station life cycle from a sustainment point of view

Science.gov (United States)

Brely, Natalie; Gautier, Jean-Pierre; Foster, Daniel

2014-05-01

The International Monitoring System (IMS) is to consist of 321 monitoring facilities, composed of four different technologies with a variety of designs and equipment types, deployed in a range of environments around the globe. The International Monitoring System is conceived to operate in perpetuity through maintenance, replacement and recapitalization of IMS facilities' infrastructure and equipment when the end of service life is reached [CTBT/PTS/INF.1163]. Life Cycle techniques and modellization are being used by the PTS to plan and forecast life cycle sustainment requirements of IMS facilities. Through historical data analysis, Engineering inputs and Feedback from experienced Station Operators, the PTS currently works towards increasing the level of confidence on these forecasts and sustainment requirements planning. Continued validation, feedback and improvement of source data from scientific community and experienced users is sought and essential in order to ensure limited effect on data availability and optimal costs (human and financial).

International Monitoring system (IMS) build-up in Africa: Current status and the way forward

International Nuclear Information System (INIS)

Basham, P.

2002-01-01

The complete IMS verification system for primary and auxiliary seismic together with that of radionuclide, hydroacoustic and infrasound is plotted on a global map and Africa in particular showing its status. IMS situation in East and Southern Africa is included

Implementing Adaptive Educational Methods with IMS Learning Design

NARCIS (Netherlands)

Specht, Marcus; Burgos, Daniel

2006-01-01

Please, cite this publication as: Specht, M. & Burgos, D. (2006). Implementing Adaptive Educational Methods with IMS Learning Design. Proceedings of Adaptive Hypermedia. June, Dublin, Ireland. Retrieved June 30th, 2006, from http://dspace.learningnetworks.org

A Mapping of the Federal Financial Institutions Examination Council (FFIEC) Cybersecurity Assessment Tool (CAT) to the Cyber Resilience Review (CRR)

Science.gov (United States)

2016-10-01

addressed. Intermediate MIL3:Q1 – all The cybersecurity function has a clear reporting line that does not present a conflict of interest. Additional...Additional guidance—FFIEC requires that all employees are made aware of how to detect and report potential cybersecurity issues. Intermediate IM:G1.Q3...correlated for trend analysis and reporting . Intermediate IM:MIL2.Q3 Employees that are essential to mitigate the risk (e.g., fraud, business resilience

Multimedia als Entwicklungsfaktor im ländlichen Raum? : Fallbeispiel Wirtschaftsregion Friedrichshafen/Bodensee

OpenAIRE

Haupenthal, Edmund; Leuninger, Stefan; Beermann, Petra; Kutter, Martina

1998-01-01

Im Rahmen der vorliegenden empirischen Studie in der Wirtschaftsregion Friedrichshafen wurden die Wechselwirkungen zwischen regionalen Strukturfaktoren und „Multimedia-Entwicklungen“ im ländlichen Raum untersucht. Die positive Multimedia-Entwicklung geht auf folgende regionale Erfolgsfaktoren zurück: die politische Akzeptanz der neuen Technologie, die Vorhaltung der Multimedia-Akademie, die regionale Nachfrage, die Verfügbarkeit ausreichenden Know-hows und Humankapitals sowie das Vorhandensei...

Emotionsregulationsstrategien und aggressives Verhalten im Kindergartenalter

OpenAIRE

Helmsen, Johanna; Petermann, Franz

2010-01-01

In der vorliegenden Studie (N = 193) wurde untersucht, ob sich körperlich und relational aggressive Kinder im Kindergartenalter (mittleres Alter: 55 Monate) in ihren Emotionsregulationsstrategien von ihren unauffälligen Altersgenossen unterscheiden. Zur Erhebung der Emotionsregulation wurde eine strukturierte, videografierte Verhaltensbeobachtung durchgeführt, in der gezielt Frustration ausgelöst wurde. Anschließend wurden Regulationsstrategien in sieben verschiedenen Kategorien ausgewertet. ...

STUDI KUALITATIF MENGENAI PERSEPSI DAN PERILAKU SEKSUAL WANITA PEKERJA SEKS KOMERSIAL (PSK DALAM UPAYA PENCEGAHAN IMS DI KOTA SEMARANG TAHUN 2012

Directory of Open Access Journals (Sweden)

Ratu Matahari

2015-04-01

Full Text Available Pendahuluan: Peningkatan jumlah kasus IMS di Kota Semarangdengan jumlah kasus IMS pada tahun 2009 tercatat mencapai 2.471 kasusdan jumlah kasus IMS pada tahun 2011 adalah 2473 kasus. Tujuan: Mendeskripsikan persepsi dan perilaku seksual wanita Pekerja Seks Komersial (PSK di Lokalisasi Sunan Kuning terhadap upaya pencegahan Infeksi Menular Seksual (IMS di Kota Semarang. Metode: Penelitian ini dilakukan dengan menggunakan teknik wawancara mendalam (indepth interview pada enam PSK yang mengalami IMS dan mewawancarai dua kelompok diskusi (FGD, seorang mucikari, dan seorang petugas lapangan (PL sebagai triangulasi. Analisis data menggunakan analisis isi (content analysis. Hasil: Pola Pengetahuan PSK dan persepsi PSK terhadap IMS juga sudah baik, tetapi perilaku PSK dalam upaya mencegah penularan IMS masih belum bisa dikatakan baik karena penggunaan kondom diantara pekerja seks komersial pada saat melakukan hubungan seksual dengan pelanggannya masih rendah. Tidak adanya dukungan dari mucikari dalam meningkatkan perilaku pencegahan IMS. Hal ini menunjukkan bahwa kepedulian terhadap kesehatan diri sendiri masih rendah. Kesimpulan: Perilaku pencegahan PSK terhadap penularan IMS belum baik. Perlu diadakan pelatihan dengan metode role playing kepada para PSK dan mucikari untuk meningkatkan kepedulian mereka terhadap kesehatan sehingga diharapkan akan terjadi perubahan perilaku baru dalam upaya pencegahan penularan IMS terhadap diri mereka sendiri atau pelanggan.  Kata kunci: Persepsi, pekerja seks komersial, IMS, Kota Semarang

Suchverhalten im Web: Empirische Ergebnisse

OpenAIRE

Schmidt-Mänz, Nadine

2005-01-01

Nadine Schmidt-Mänz vom Institut für Entscheidungstheorie u. Unternehmensforschung, Universität Karlsruhe, berichtete über „Suchverhalten im Web: Empirische Ergebnisse“. Rund 6000 Benutzer von Suchmaschinen füllten den von ihr hergestellten Online-Fragebogen aus. Einige ihrer Erkenntnisse: Als Suchmaschine wurde mit 91,3 % Google benutzt. Die Monopolstellung von Google war den Suchenden nicht bewußt. Einer der Schlüsse der Referentin: Es mangelt nicht an Suchmaschinen, sondern an der „Weitere...

Artroscopia del hombro: Técnica e imágenes

OpenAIRE

ARANGO GARCIA, GASTON; ALVAREZ CAMBRAS, RODRIGO; LOPEZ CABRERA, JOSE RAMON; MIRANDEZ OLARAN, HUGO; LARA VALDIVIA, JESUS

1995-01-01

En este trabajo se muestra cómo realizar la técnica de la artroscopia de la articulación del hombro. Se presentan vistas de las imágenes artroscópicas y de la anatomía normal de la articulación para ayudar a la interpretación e identificación de las imágenes patológicas más comúnmente encontradas. Se realizó la técnica en 8 pacientes, deportistas con hombros dolorosos, en los cuales el diagnóstico clínico no era certero. Este trabajo se realizó en 1990 para introducir la técnica artroscópica ...

Systeme im Einsatz. Lernmanagement, Kompetenzmanagement und PLE

NARCIS (Netherlands)

Kalz, Marco; Schön, Sandra; Lindner, Martin; Roth, Detlev; Baumgartner, Peter

2011-01-01

Kalz, M., Schön, S., Lindner, M., Roth, D., & Baumgartner, P. (2011). Systeme im Einsatz. Lernmanagement, Kompetenzmanagement und PLE. In M. Ebner, & S. Schön (Eds.), L3T - Lerhbuch für Lernen und Lehren mit Technologie (pp. 111-118). Graz, Austria: Uni Graz. Available at

How IMS Enables Converged Services for Cable and 3G Technologies: A Survey

Directory of Open Access Journals (Sweden)

Noël Crespi

2008-04-01

Full Text Available The IP multimedia subsystem (IMS is a service control overlay standardized by the 3GPP. The IMS is based on session initiation protocol (SIP to establish, modify, and terminate the sessions. It provides a clean separation between services, signaling, and media with the potential to enable control and management of services over multiple transport technologies. In the scope of fixed-mobile convergence, this paper is dedicated to presenting a review of how cable networks can be integrated into IMS technology to achieve 3G-cable horizontal convergence. Cable networks, as one of the major fixed broadband access technologies with PacketCable architecture, are able to provide broadband internet access and VoIP in addition to cable TV. In this article, we review the evolution in PacketCable architecture to take up IMS. In this way, we consider the standardization and research activities to address this integration. We review some important challenges such as SIP protocol compatibility, defining unique user profile, required enhancement in authentication process, QoS and charging system.

How IMS Enables Converged Services for Cable and 3G Technologies: A Survey

Directory of Open Access Journals (Sweden)

Mani Mehdi

2008-01-01

Full Text Available The IP multimedia subsystem (IMS is a service control overlay standardized by the 3GPP. The IMS is based on session initiation protocol (SIP to establish, modify, and terminate the sessions. It provides a clean separation between services, signaling, and media with the potential to enable control and management of services over multiple transport technologies. In the scope of fixed-mobile convergence, this paper is dedicated to presenting a review of how cable networks can be integrated into IMS technology to achieve 3G-cable horizontal convergence. Cable networks, as one of the major fixed broadband access technologies with PacketCable architecture, are able to provide broadband internet access and VoIP in addition to cable TV. In this article, we review the evolution in PacketCable architecture to take up IMS. In this way, we consider the standardization and research activities to address this integration. We review some important challenges such as SIP protocol compatibility, defining unique user profile, required enhancement in authentication process, QoS and charging system.

Evaluation of the Indian Migration Study Physical Activity Questionnaire (IMS-PAQ: a cross-sectional study

Directory of Open Access Journals (Sweden)

Sullivan Ruth

2012-02-01

Full Text Available Abstract Background Socio-cultural differences for country-specific activities are rarely addressed in physical activity questionnaires. We examined the reliability and validity of the Indian Migration Study Physical Activity Questionnaire (IMS-PAQ in urban and rural groups in India. Methods A sub-sample of IMS participants (n = 479 was used to examine short term (≤1 month [n = 158] and long term (> 1 month [n = 321] IMS-PAQ reliability for levels of total, sedentary, light and moderate/vigorous activity (MVPA intensity using intraclass correlation (ICC and kappa coefficients (k. Criterion validity (n = 157 was examined by comparing the IMS-PAQ to a uniaxial accelerometer (ACC worn ≥4 days, via Spearman's rank correlations (ρ and k, using Bland-Altman plots to check for systematic bias. Construct validity (n = 7,000 was established using linear regression, comparing IMS-PAQ against theoretical constructs associated with physical activity (PA: BMI [kg/m2], percent body fat and pulse rate. Results IMS-PAQ reliability ranged from ICC 0.42-0.88 and k = 0.37-0.61 (≤1 month and ICC 0.26 to 0.62; kappa 0.17 to 0.45 (> 1 month. Criterion validity was ρ = 0.18-0.48; k = 0.08-0.34. Light activity was underestimated and MVPA consistently and substantially overestimated for the IMS-PAQ vs. the accelerometer. Criterion validity was moderate for total activity and MVPA. Reliability and validity were comparable for urban and rural participants but lower in women than men. Increasing time spent in total activity or MVPA, and decreasing time in sedentary activity were associated with decreasing BMI, percent body fat and pulse rate, thereby demonstrating construct validity. Conclusion IMS-PAQ reliability and validity is similar to comparable self-reported instruments. It is an appropriate tool for ranking PA of individuals in India. Some refinements may be required for sedentary populations and women in India.

Metabolism of the synthetic cannabinoids AMB-CHMICA and 5C-AKB48 in pooled human hepatocytes and rat hepatocytes analyzed by UHPLC-(IMS)-HR-MSE

DEFF Research Database (Denmark)

Mardal, Marie; Dalsgaard, Petur Weihe; Qi, Bing

2018-01-01

metabolites of the synthetic cannabinoids, AMB-CHMICA and 5C-AKB48, using an in silico-assisted workflow with analytical data acquired using ultra-high-performance liquid chromatography–(ion mobility spectroscopy)–high resolution–mass spectrometry in data-independent acquisition mode (UHPLC......-(IMS)-HR-MSE). The metabolites were identified after incubation with rat and pooled human hepatocytes using UHPLC-HR-MSE, followed by UHPLC-IMS-HR-MSE. Metabolites of AMB-CHMICA and 5C-AKB48 were predicted with Meteor (Lhasa Ltd) and imported to the UNIFI software (Waters). The predicted metabolites were assigned to analytical...... components supported by the UNIFI in silico fragmentation tool. The main metabolic pathway of AMB-CHMICA was O-demethylation and hydroxylation of the methylhexyl moiety. For 5C-AKB48, the main metabolic pathways were hydroxylation(s) of the adamantyl moiety and oxidative dechlorination with subsequent...

An IMS-Based Middleware Solution for Energy-Efficient and Cost-Effective Mobile Multimedia Services

Science.gov (United States)

Bellavista, Paolo; Corradi, Antonio; Foschini, Luca

Mobile multimedia services have recently become of extreme industrial relevance due to the advances in both wireless client devices and multimedia communications. That has motivated important standardization efforts, such as the IP Multimedia Subsystem (IMS) to support session control, mobility, and interoperability in all-IP next generation networks. Notwithstanding the central role of IMS in novel mobile multimedia, the potential of IMS-based service composition for the development of new classes of ready-to-use, energy-efficient, and cost-effective services is still widely unexplored. The paper proposes an original solution for the dynamic and standard-compliant redirection of incoming voice calls towards WiFi-equipped smart phones. The primary design guideline is to reduce energy consumption and service costs for the final user by automatically switching from the 3G to the WiFi infrastructure whenever possible. The proposal is fully compliant with the IMS standard and exploits the recently released IMS presence service to update device location and current communication opportunities. The reported experimental results point out that our solution, in a simple way and with full compliance with state-of-the-art industrially-accepted standards, can significantly increase battery lifetime without negative effects on call initiation delay.

Features of Red Sea Water Masses

Science.gov (United States)

Kartadikaria, Aditya; Hoteit, Ibrahim

2015-04-01

Features of Red Sea water mass can be divided into three types but best to be grouped into two different classes that are split at the potential density line σθ=27.4. The surface water (0-50 m) and the intermediate water (50-200 m) have nearly identical types of water mass. They appear as a maxima salinity layer for the water mass that has σθ > 26.0, and as a minimum salinity layer for water mass that has σθ water masses are strongly affected by mixing that is controlled by seasonal variability, fresh water intrusion of the Gulf of Aden Intermediate Water (GAIW), and eddies variability. Two types of mixing; isopycnal and diapycnal mixing are part of important physical phenomena that explain the change of water mass in the Red Sea. The isopycnal mixing occurs at the neutral potential density line, connecting the Red Sea with its adjacent channel, the Gulf of Aden. Diapycnal mixing is found as a dominant mixing mode in the surface of the Red Sea Water and mainly due to energetic eddy activity. Density gradients, across which diapycnal mixing occurs, in the Red Sea are mainly due to large variations in salinity. The isolation of an extreme haline water mass below the thermocline contributes to the generation of the latitudinal shift and low diapycnal mixing. This finding further explains the difference of spatial kinetic mixing between the RSW and the Indian Ocean basin.

Features of Red Sea Water Masses

KAUST Repository

Kartadikaria, Aditya R.

2015-04-01

Features of Red Sea water mass can be divided into three types but best to be grouped into two different classes that are split at the potential density line σθ=27.4. The surface water (0-50 m) and the intermediate water (50-200 m) have nearly identical types of water mass. They appear as a maxima salinity layer for the water mass that has σθ > 26.0, and as a minimum salinity layer for water mass that has σθ < 26.0. These types of water masses are strongly affected by mixing that is controlled by seasonal variability, fresh water intrusion of the Gulf of Aden Intermediate Water (GAIW), and eddies variability. Two types of mixing; isopycnal and diapycnal mixing are part of important physical phenomena that explain the change of water mass in the Red Sea. The isopycnal mixing occurs at the neutral potential density line, connecting the Red Sea with its adjacent channel, the Gulf of Aden. Diapycnal mixing is found as a dominant mixing mode in the surface of the Red Sea Water and mainly due to energetic eddy activity. Density gradients, across which diapycnal mixing occurs, in the Red Sea are mainly due to large variations in salinity. The isolation of an extreme haline water mass below the thermocline contributes to the generation of the latitudinal shift and low diapycnal mixing. This finding further explains the difference of spatial kinetic mixing between the RSW and the Indian Ocean basin.

Antisemitismus, Shoah und deutsche Verantwortung:(Nach)Wirkungen des Nationalsozialismus im medialen Nahostdiskurs

OpenAIRE

Ullrich, Peter

2010-01-01

Wahrscheinlich wird kein anderer internationaler Konflikt derart kontrovers und emotional in der bundesrepublikanischen Öffentlichkeit sowie auch und gerade in der politischen Linken diskutiert wie der israelisch-palästinensische oder weiter gefasst, der Nahost-Konflikt. Aus diesem Grund nimmt dieses Thema einen besonderen Platz in der Bildungsarbeit der Rosa-Luxemburg- Stiftung im Inland wie im Ausland ein. Wenngleich dabei auch in der Stiftung und ihrem Umfeld die Meinungen auseinandergehen...

EASI-IMS an expedite and secure technique to screen for 25I-NBOH in blotter papers.

Science.gov (United States)

de Morais, Damila Rodrigues; Barbosa, Ingrid Lopes; Cunha, Kelly Francisco; Tripodi, Guilherme Lucas; Angolini, Célio Fernando Figueiredo; Franco, Marcos Fernando; de Aquino, Elvis Medeiros; Eberlin, Marcos Nogueira; Costa, Jose Luiz

2017-10-01

The increasing number of new psychoactive substances (NPS) and their quick worldwide spreading, often only slightly modified in the form of new derivatives and analogues, have brought the need for fast, wide-ranging, and unequivocal identification methods in clinical and forensic investigations. Because it usually provides secure results, gas chromatography coupled to mass spectrometry (GC-MS) has been routinely employed as the standard technique for the detection of NPS in blotter papers. For 25I-NBOH (N-(2-hydroxybenzyl)-2-(4-iodo-2,5-dimethoxyphenyl)ethan-1-aminium), however, GC-MS analysis of an blotter paper extract leads to incorrect results. In this work, we investigated whether easy ambient sonic-spray mass spectrometry imaging (EASI-IMS), and ambient ionization MS method can be applied directly to the surface of the sample requiring therefore no extraction or sample preparations, would serve as an efficient, sensitive, and secure alternative for 25I-NBOH screening. Copyright © 2017 John Wiley & Sons, Ltd.

Ammonium Sulfate Improves Detection of Hydrophilic Quaternary Ammonium Compounds through Decreased Ion Suppression in Matrix-Assisted Laser Desorption/Ionization Imaging Mass Spectrometry.

Science.gov (United States)

Sugiyama, Eiji; Masaki, Noritaka; Matsushita, Shoko; Setou, Mitsutoshi

2015-11-17

Hydrophilic quaternary ammonium compounds (QACs) include derivatives of carnitine (Car) or choline, which are known to have essential bioactivities. Here we developed a technique for improving the detection of hydrophilic QACs using ammonium sulfate (AS) in matrix-assisted laser desorption/ionization-imaging mass spectrometry (MALDI-IMS). In MALDI mass spectrometry for brain homogenates, the addition of AS greatly increased the signal intensities of Car, acetylcarnitine (AcCar), and glycerophosphocholine (GPC) by approximately 300-, 700-, and 2500-fold. The marked improvement required a higher AS concentration than that needed for suppressing the potassium adduction on phosphatidylcholine and 2,5-dihydroxybenzoic acid. Adding AS also increased the signal intensities of Car, AcCar, and GPC by approximately 10-, 20-, and 40-fold in MALDI-IMS. Consequently, the distributions of five hydrophilic QACs (Car, AcCar, GPC, choline, and phosphocholine) were simultaneously visualized by this technique. The distinct mechanism from other techniques such as improved matrix application, derivatization, or postionization suggests the great potential of AS addition to achieve higher sensitivity of MALDI-IMS for various analytes.

WIYN OPEN CLUSTER STUDY. XXIV. STELLAR RADIAL-VELOCITY MEASUREMENTS IN NGC 6819

International Nuclear Information System (INIS)

Tabetha Hole, K.; Geller, Aaron M.; Mathieu, Robert D.; Meibom, Soeren; Platais, Imants; Latham, David W.

2009-01-01

We present the current results from our ongoing radial-velocity (RV) survey of the intermediate-age (2.4 Gyr) open cluster NGC 6819. Using both newly observed and other available photometry and astrometry, we define a primary target sample of 1454 stars that includes main-sequence, subgiant, giant, and blue straggler stars, spanning a magnitude range of 11 ≤V≤ 16.5 and an approximate mass range of 1.1-1.6 M sun . Our sample covers a 23 arcminute (13 pc) square field of view centered on the cluster. We have measured 6571 radial velocities for an unbiased sample of 1207 stars in the direction of the open cluster NGC 6819, with a single-measurement precision of 0.4 km s -1 for most narrow-lined stars. We use our RV data to calculate membership probabilities for stars with ≥3 measurements, providing the first comprehensive membership study of the cluster core that includes stars from the giant branch through the upper main sequence. We identify 480 cluster members. Additionally, we identify velocity-variable systems, all of which are likely hard binaries that dynamically power the cluster. Using our single cluster members, we find a cluster average RV of 2.34 ± 0.05 km s -1 . We use our kinematic cluster members to construct a cleaned color-magnitude diagram from which we identify rich giant, subgiant, and blue straggler populations and a well defined red clump. The cluster displays a morphology near the cluster turnoff clearly indicative of core convective overshoot. Finally, we discuss a few stars of note, one of which is a short-period red-clump binary that we suggest may be the product of a dynamical encounter.

Intermediality and media change

OpenAIRE

2012-01-01

This book is about intermediality as an approach to analysing and understanding media change. Intermediality and Media Change is critical of technological determinism that characterises 'new media discourse' about the ongoing digitalization, framed as a revolution and creating sharp contrasts between old and new media. Intermediality instead emphasises paying attention to continuities between media of all types and privileges a comparative perspective on technological changes in media over ti...

Analysis for mass distribution of proton-induced reactions in intermediate energy range

CERN Document Server

Xiao Yu Heng

2002-01-01

The mass and charge distribution of residual products produced in the spallation reactions needs to be studied, because it can provide useful information for the disposal of nuclear waste and residual radioactivity generated by the spallation neutron target system. In present work, the Many State Dynamical Model (MSDM) is based on the Cascade-Exciton Model (CEM). The authors use it to investigate the mass distribution of Nb, Au and Pb proton-induced reactions in energy range from 100 MeV to 3 GeV. The agreement between the MSDM simulations and the measured data is good in this energy range, and deviations mainly show up in the mass range of 90 - 150 for the high energy proton incident upon Au and Pb

The Effect of Collimating Lens Focusing on Laser Beam Shape in Matrix Assisted Laser Desorption/Ionization Mass Spectrometry (MALDI-MS).

Science.gov (United States)

O'Rourke, Matthew B; Raymond, Benjamin B A; Djordjevic, Steven P; Padula, Matthew P

2018-03-01

Tissue imaging using matrix assisted laser desorption/ionization mass spectrometry (MALDI-MS) is a well-established technique that, in recent years, has seen wider adoption and novel application. Applications such imaging mass spectrometry (IMS) and biotyping are beginning to gain greater exposure and use; however, with limitations in optimization methods, producing the best result often relies on the ability to customize the physical characteristics of the instrumentation, a task that is challenging for most mass spectrometry laboratories. With this in mind, we have described the effect of making simple adjustments to the laser optics at the final collimating lens area, to adjust the laser beam size and shape in order to allow greater customization of the instrument for improving techniques such as IMS. We have therefore been able to demonstrate that improvements can be made without requiring the help of an electrical engineer or external funding in a way that only costs a small amount of time. Graphical Abstract ᅟ.

Medien im Lehramtsstudium für die Sekundarstufe in Österreich. Eine quantitativ-inhaltsanalytische Lehrplananalyse von vier Curricula.

Directory of Open Access Journals (Sweden)

Christian Swertz

2015-12-01

Full Text Available Medien sind für Erziehung und Unterricht notwendig sowie im Alltag, in der Politik und der Ökonomie relevant. Daher ist zu erwarten, dass Medien in den Curricula für die Lehramtsausbildung im Sekundarbereich vorkommen. Ob diese Erwartung zutrifft, wird an vier Curricula für den Sekundarbereich mit einem quantitativen inhaltsanalytischen Verfahren untersucht. Die Ergebnisse zeigen, dass Medien im Allgemeinen und Medienpädagogik, Medienkompetenz und Mediendidaktik im Besonderen nur selten vorkommen und die meisten der seltenen Vorkommnisse irrelevant sind.

VizieR Online Data Catalog: Adiabatic mass loss in binary stars. II. (Ge+, 2015)

Science.gov (United States)

Ge, H.; Webbink, R. F.; Chen, X.; Han, Z.

2016-02-01

In the limit of extremely rapid mass transfer, the response of a donor star in an interacting binary becomes asymptotically one of adiabatic expansion. We survey here adiabatic mass loss from Population I stars (Z=0.02) of mass 0.10M⊙-100M⊙ from the zero-age main sequence to the base of the giant branch, or to central hydrogen exhaustion for lower main sequence stars. The logarithmic derivatives of radius with respect to mass along adiabatic mass-loss sequences translate into critical mass ratios for runaway (dynamical timescale) mass transfer, evaluated here under the assumption of conservative mass transfer. For intermediate- and high-mass stars, dynamical mass transfer is preceded by an extended phase of thermal timescale mass transfer as the star is stripped of most of its envelope mass. The critical mass ratio qad (throughout this paper, we follow the convention of defining the binary mass ratio as q{equiv}Mdonor/Maccretor) above which this delayed dynamical instability occurs increases with advancing evolutionary age of the donor star, by ever-increasing factors for more massive donors. Most intermediate- or high-mass binaries with nondegenerate accretors probably evolve into contact before manifesting this instability. As they approach the base of the giant branch, however, and begin developing a convective envelope, qad plummets dramatically among intermediate-mass stars, to values of order unity, and a prompt dynamical instability occurs. Among low-mass stars, the prompt instability prevails throughout main sequence evolution, with qad declining with decreasing mass, and asymptotically approaching qad=2/3, appropriate to a classical isentropic n=3/2 polytrope. Our calculated qad values agree well with the behavior of time-dependent models by Chen & Han (2003MNRAS.341..662C) of intermediate-mass stars initiating mass transfer in the Hertzsprung gap. Application of our results to cataclysmic variables, as systems that must be stable against rapid mass

Mass differences of light hadron isomultiplets

International Nuclear Information System (INIS)

Palladino, B.E.; Ferreira, P.L.

1989-01-01

Mass differences of low-lying, non-strange, hadron isomultiplets are investigated in the framework of a relativistic, independent quark potential model, implemented by center-of-mass, one-gluon-exchange and pion-cloud corrections. The introduction of pionic self-energy corrections with non-degenerate intermediate states is instrumental in our analysis, playing also a fundamental role for a successful description of the ρ-ω mass splitting. The effect of the supersposition of all these corrections is discussed in some detail for the p-n, Π + -Π 0 , ρ + -ρ 0 and Δ ++ -Δ 0 mass differences. The corresponding hadronic masses are also calculated with suitable values for the hardronic sizes and quark masses. (author) [pt

The optimum intermediate pressure of two-stages vapor compression refrigeration cycle for Air-Conditioning unit

Science.gov (United States)

Ambarita, H.; Sihombing, H. V.

2018-03-01

Vapor compression cycle is mainly employed as a refrigeration cycle in the Air-Conditioning (AC) unit. In order to save energy, the Coefficient of Performance (COP) of the need to be improved. One of the potential solutions is to modify the system into multi-stages vapor compression cycle. The suitable intermediate pressure between the high and low pressures is one of the design issues. The present work deals with the investigation of an optimum intermediate pressure of two-stages vapor compression refrigeration cycle. Typical vapor compression cycle that is used in AC unit is taken into consideration. The used refrigerants are R134a. The governing equations have been developed for the systems. An inhouse program has been developed to solve the problem. COP, mass flow rate of the refrigerant and compressor power as a function of intermediate pressure are plotted. It was shown that there exists an optimum intermediate pressure for maximum COP. For refrigerant R134a, the proposed correlations need to be revised.

Intermediate Fragment

DEFF Research Database (Denmark)

Kruse Aagaard, Anders

2015-01-01

This text and its connected exhibition are aiming to reflect both on the thoughts, the processes and the outcome of the design and production of the artefact ‘Intermediate Fragment’ and making as a contemporary architectural tool in general. Intermediate Fragment was made for the exhibition ‘Enga...... of realising an exhibition object was conceived, but expanded, refined and concretised through this process. The context of the work shown here is an interest in a tighter, deeper connection between experimentally obtained material knowledge and architectural design....

Governance-Default Risk Relationship and the Demand for Intermediated and Non-Intermediated Debt

Directory of Open Access Journals (Sweden)

Husam Aldamen

2012-09-01

Full Text Available This paper explores the impact of corporate governance on the demand for intermediated debt (asset finance, bank debt, non-bank private debt and non-intermediated debt (public debt in the Australian debt market. Relative to other countries the Australian debt market is characterised by higher proportions of intermediated or private debt with a lower inherent level of information asymmetry in that private lenders have greater access to financial information (Gray, Koh & Tong 2009. Our firm level, cross-sectional evidence suggests that higher corporate governance impacts demand for debt via the mitigation of default risk. However, this relationship is not uniform across all debt types. Intermediated debt such as bank and asset finance debt are more responsive to changes in governance-default risk relationship than non-bank and non-intermediated debt. The implication is that a firm’s demand for different debt types will reflect its governance-default risk profile.

Conventional and Advanced Separations in Mass Spectrometry-Based Metabolomics: Methodologies and Applications

Energy Technology Data Exchange (ETDEWEB)

Heyman, Heino M.; Zhang, Xing; Tang, Keqi; Baker, Erin Shammel; Metz, Thomas O.

2016-02-16

Metabolomics is the quantitative analysis of all metabolites in a given sample. Due to the chemical complexity of the metabolome, optimal separations are required for comprehensive identification and quantification of sample constituents. This chapter provides an overview of both conventional and advanced separations methods in practice for reducing the complexity of metabolite extracts delivered to the mass spectrometer detector, and covers gas chromatography (GC), liquid chromatography (LC), capillary electrophoresis (CE), supercritical fluid chromatography (SFC) and ion mobility spectrometry (IMS) separation techniques coupled with mass spectrometry (MS) as both uni-dimensional and as multi-dimensional approaches.

La política de las imágenes en Jacques Rancière

OpenAIRE

Corella Lacasa, Miguel

2011-01-01

Someto hoy a discusión la crónica de mi particular recorrido fragmentario e inacabado por la obra de Rancière, que organizaré a partir algunas de las imágenes que, en mi opinión, juegan un papel importante en su argumenta ción. Espero que este álbum de imágenes y el discurso tramado a partir de ellas puedan ser de alguna utilidad para el debate acerca del sentido o el uso político de las imágenes y, más en general, para la discusión de las relaciones entre estética y po...

Veränderungen der Serumlipide bei Senioren im Verlauf des Alterns unter Berücksichtigung ausgewählter Einflussfaktoren : eine Untersuchung im Rahmen der Gießener Senioren Langzeitstudie

OpenAIRE

Richter, Margrit

2014-01-01

In der vorliegenden Arbeit wurde im Rahmen der Giessener Senioren Langzeitstudie (GISELA) untersucht, ob und in wie weit sich die Konzentrationen der Serumlipide (Gesamtcholesterol (TC), HDL-Cholesterol (HDL-C), LDL-Cholesterol (LDL-C), NonHDL-Cholesterol (NonHDL-C) und Triglyceride (TG)) im Verlauf fortgeschrittenen Alterns verändern. Dabei wurden folgende mögliche Einflussfaktoren berücksichtigt: BMI, WHR, PAI, Fettmasse, Kohlenhydrat¬zufuhr, Ballaststoffzufuhr, Zufuhr mehrfach ungesättigte...

Datamart use for complex data retrieval in an ArcIMS application

Energy Technology Data Exchange (ETDEWEB)

Scherma, S. (Steven); Bolivar, Stephen L.

2004-01-01

This paper describes the use of datamarts and data warehousing concepts to expedite retrieval and display of complex attribute data from multi-million record databases. Los Alamos National Laboratory has developed an Internet application (SMART) using ArcIMS that relies on datamarts to quickly retrieve attribute data, associated with, but not contained within GIS layers. The volume of data and the complex relationships within the transactional database made data display within ArcIMS impractical without the use of datamarts. The technical issues and solutions involved in the development are discussed.

An Effective Method to Detect Volatile Intermediates Generated in the Bioconversion of Coal to Methane by Gas Chromatography-Mass Spectrometry after In-Situ Extraction Using Headspace Solid-Phase Micro-Extraction under Strict Anaerobic Conditions.

Science.gov (United States)

Liu, Jianmin; Wang, Baoyu; Tai, Chao; Wu, Li; Zhao, Han; Guan, Jiadong; Chen, Linyong

2016-01-01

Bioconversion of coal to methane has gained increased attention in recent decades because of its economic and environmental advantages. However, the mechanism of this process is difficult to study in depth, partly because of difficulties associated with the analysis of intermediates generated in coal bioconversion. In this investigation, we report on an effective method to analyze volatile intermediates generated in the bioconversion of coal under strict anaerobic conditions. We conduct in-situ extraction of intermediates using headspace solid-phase micro-extraction followed by detection by gas chromatography-mass spectrometry. Bioconversion simulation equipment was modified and combined with a solid-phase micro-extraction device. In-situ extraction could be achieved by using the combined units, to avoid a breakdown in anaerobic conditions and to maintain the experiment continuity. More than 30 intermediates were identified qualitatively in the conversion process, and the variation in trends of some typical intermediates has been discussed. Volatile organic acids (C2-C7) were chosen for a quantitative study of the intermediates because of their importance during coal bioconversion to methane. Fiber coating, extraction time, and solution acidity were optimized in the solid-phase micro-extraction procedure. The pressure was enhanced during the bioconversion process to investigate the influence of headspace pressure on analyte extraction. The detection limits of the method ranged from 0.0006 to 0.02 mmol/L for the volatile organic acids and the relative standard deviations were between 4.6% and 11.5%. The volatile organic acids (C2-C7) generated in the bioconversion process were 0.01-1.15 mmol/L with a recovery range from 80% to 105%. The developed method is useful for further in-depth research on the bioconversion of coal to methane.

Security in the internet; Sicherheitsaspekte im Internet

Energy Technology Data Exchange (ETDEWEB)

Seibel, R.M.M.; Kocher, K.; Landsberg, P. [Witten-Herdecke Univ., Witten (Germany). Inst. fuer Diagnostische und Interventionelle Radiologie

2000-04-01

Aim of the study: Is it possible to use the Internet as a secure media for transport of telemedicine? Which risks exist for routine use? In this article state of the art methods of security were analysed. Telemedicine in the Internet has severe risks, because patient data and hospital data of a secure Intranet can be manipulated by connecting it to the Web. Conclusions: Establishing of a firewall and the introduction of HPC (Health Professional Card) are minimizing the risk of un-authorized access to the hospital server. HPC allows good safety with digital signature and authentication of host and client of medical data. For secure e-mail PGP (Pretty Good Privacy) is easy to use as a standard protocol. Planning all activities exactly as well as following legal regulations are important requisites for reduction of safety risks in Internet. (orig.) [German] Ziele der Studie und Analyse: Es sollten die Fragen beantwortet werden, ob es moeglich ist, das Internet als sicheres Uebermittlungsmedium fuer Telemedizin zu nutzen und welche Sicherheitsrisiken bestehen. Dazu wurden die gaengigen Sicherheitsmethoden analysiert. Telemedizin im Internet ist mit Sicherheitsrisiken behaftet, die durch die Oeffnung eines Intranets mit der Moeglichkeit zur unberechtigten Manipulation von aussen bedingt sind. Schlussfolgerung: Diese Sicherheitsrisiken koennen durch eine Firewall weitgehend unterbunden werden. Chipkarten wie die Health professional card ermoeglichen eine hohe Sicherheit bei digitaler Signatur und sicherer Authentifikation der Sender und Empfaenger von Daten im Internet. Auch Standards wie Pretty good privacy sind inzwischen fuer sichere e-mails einfach einzusetzen. Wichtige Voraussetzung fuer die Reduktion von Sicherheitsrisiken ist unter Beruecksichtigung der gesetzlichen Vorgaben die exakte Planung aller Aktivitaeten im Internet, bei denen medizinische Patientendaten versandt werden sollen, in einem Team aus Aerzten und Informatikern. (orig.)

Dynamik des Kaufverhaltens im Bio-Sortiment

OpenAIRE

Buder, Fabian; Hamm, Ulrich; Bickel, Malte; Bien, Barbara; Michels, Paul

2010-01-01

Das Gesamtziel des vorliegenden Forschungsprojekts war es, eine detaillierte Informationsgrundlage zum tatsächlichen Kaufverhalten von deutschen Haushalten bei ökologischen Lebensmitteln auf der Basis von Haushaltspaneldaten zu erstellen. Dazu sollten zum einen relevante Aspekte des Kaufverhaltens von Haushalten bei Öko-Lebensmitteln im Zeitverlauf von 2004 bis 2008 analysiert und zum anderen die Einflussfaktoren des Kaufverhaltens bei Öko-Lebensmitteln für das Jahr 2008 identifiziert werden....

Gewerbsmässigkeit im schweizerischen Luftrecht

OpenAIRE

Müller, Roland

2005-01-01

Der Begriff der Gewerbsmässigkeit hat im schweizerischen Luftrecht eine grosse Bedeutung. Werden gewerbsmässige Flüge ohne die entsprechenden Bewilligungen und Voraussetzungen durchgeführt, so resultieren gravierende zivilrechtliche, strafrechtliche und administrative Konsequenzen. In den massgebenden internationalen Luftfahrtabkommen findet sich keine Definition der Gewerbsmässigkeit, dies wird den einzelnen Staaten überlassen. Nur in den Joint Aviation Requirements und in der EU-Zollver...

Multifragmentation in intermediate energy 129Xe-induced heavy-ion reactions

International Nuclear Information System (INIS)

Tso, Kin.

1996-05-01

The 129 Xe-induced reactions on nat Cu, 89 Y, 165 Ho, and 197 Au at bombarding energies of E/A = 40 ampersand 60 MeV have been studied theoretically and experimentally in order to establish the underlying mechanism of multifragmentation at intermediate energy heavy-Ion collisions. Nuclear disks formed in central heavy-ion collisions, as simulated by means of Boltzmann-like kinetic equations, break up into several fragments due to a new kind of Rayleigh-like surface instability. A sheet of liquid, stable in the limit of non-interacting surfaces, is shown to become unstable due to surface-surface interactions. The onset of this instability is determined analytically. A thin bubble behaves like a sheet and is susceptible to the surface instability through the crispation mode. The Coulomb effects associated with the depletion of charges in the central cavity of nuclear bubbles are investigated. The onset of Coulomb instability is demonstrated for perturbations of the radial mode. Experimental intermediate-mass-fragment multiplicity distributions for the 129 Xe-induced reactions are shown to be binomial at each transverse energy. From these distributions, independent of the specific target, an elementary binary decay probability p can be extracted that has a thermal dependence. Thus it is inferred that multifragmentation is reducible to a combination of nearly independent emission processes. If sequential decay is assumed, the increase of p with transverse energy implies a contraction of the emission time scale. The sensitivity of p to the lower Z threshold in the definition of intermediate-mass-fragments points to a physical Poisson simulations of the particle multiplicities show that the weak auto-correlation between the fragment multiplicity and the transverse energy does not distort a Poisson distribution into a binomial distribution. The effect of device efficiency on the experimental results has also been studied

Identification of phase-II metabolites of flavonoids by liquid chromatography-ion-mobility spectrometry-mass spectrometry.

Science.gov (United States)

Chalet, Clément; Hollebrands, Boudewijn; Janssen, Hans-Gerd; Augustijns, Patrick; Duchateau, Guus

2018-01-01

Flavonoids are a class of natural compounds with a broad range of potentially beneficial health properties. They are subjected to an extensive intestinal phase-II metabolism, i.e., conjugation to glucuronic acid, sulfate, and methyl groups. Flavonoids and their metabolites can interact with drug transporters and thus interfere with drug absorption, causing food-drug interactions. The site of metabolism plays a key role in the activity, but the identification of the various metabolites remains a challenge. Here, we developed an analytical method to identify the phase-II metabolites of structurally similar flavonoids. We used liquid chromatography-ion-mobility spectrometry-mass spectrometry (LC-IMS-MS) analysis to identify phase-II metabolites of flavonols, flavones, and catechins produced by HT29 cells. We showed that IMS could bring valuable structural information on the different positional isomers of the flavonols and flavones. The position of the glucuronide moiety had a strong influence on the collision cross section (CCS) of the metabolites, with only minor contribution of hydroxyl and methyl moieties. For the catechins, fragmentation data obtained from MS/MS analysis appeared more useful than IMS to determine the structure of the metabolites, mostly due to the high number of metabolites formed. Nevertheless, CCS information as a molecular fingerprint proved to be useful to identify peaks from complex mixtures. LC-IMS-MS thus appears as a valuable tool for the identification of phase-II metabolites of flavonoids. Graphical abstract Structural identification of phase-II metabolites of flavonoids using LC-IMS-MS.

ImBuild: Impact of building energy efficiency programs

Energy Technology Data Exchange (ETDEWEB)

Scott, M.J.; Hostick, D.J.; Belzer, D.B.

1998-04-01

As part of measuring the impact of government programs on improving the energy efficiency of the Nation`s building stock, the Department of Energy Office of Building Technology, State and Community Programs (BTS) is interested in assessing the economic impacts of its portfolio of programs, specifically the potential impact on national employment and income. The special-purpose version of the IMPLAN model used in this study is called ImBuild. In comparison with simple economic multiplier approaches, such as Department of Commerce RIMS 2 system, ImBuild allows for more complete and automated analysis of the economic impacts of energy efficiency investments in buildings. ImBuild is also easier to use than existing macroeconomic simulation models. The authors conducted an analysis of three sample BTS energy programs: the residential generator-absorber heat exchange gas heat pump (GAX heat pump), the low power sulfur lamp (LPSL) in residential and commercial applications, and the Building America program. The GAX heat pump would address the market for the high-efficiency residential combined heating and cooling systems. The LPSL would replace some highly efficient fluorescent commercial lighting. Building America seeks to improve the energy efficiency of new factory-built, modular, manufactured, and small-volume, site-built homes through use of systems engineering concepts and early incorporation of new products and processes, and by increasing the demand for more energy-efficient homes. The authors analyze a scenario for market penetration of each of these technologies devised for BTS programs reported in the BTS GPRA Metrics Estimates, FY99 Budget Request, December 19, 1997. 46 figs., 4 tabs.

Die nonverbale Kommunikation im Bundestagswahlkampf 2002:Gerhard Schröder versus Edmund Stoiber

OpenAIRE

Dieball, W. (Werner)

2004-01-01

Diese interdisziplinäre Dissertation aus dem Fachbereich Politikwissenschaften verfolgt vordergründig das Ziel, die Wirkungsweise der nonverbalen Kommunikation im Bundestagswahlkampf 2002 zu analysieren. Im Zentrum der empirisch-analytischen Untersuchung stehen Gerhard Schröder und Edmund Stoiber, die nach den nonverbalen Merkmalen: äußeres Erscheinungsbild, Mimik, Stimmklang, Gestik und Motorik untersucht werden. Das leitende Forschungsinteresse der Arbeit besteht darin, zu eruieren, inwiewe...

A Derivatization and Validation Strategy for Determining the Spatial Localization of Endogenous Amine Metabolites in Tissues using MALDI Imaging Mass Spectrometry

Science.gov (United States)

Manier, M. Lisa; Spraggins, Jeffrey M.; Reyzer, Michelle L.; Norris, Jeremy L.; Caprioli, Richard M.

2014-01-01

Imaging mass spectrometry (IMS) studies increasingly focus on endogenous small molecular weight metabolites and consequently bring special analytical challenges. Since analytical tissue blanks do not exist for endogenous metabolites, careful consideration must be given to confirm molecular identity. Here we present approaches for the improvement in detection of endogenous amine metabolites such as amino acids and neurotransmitters in tissues through chemical derivatization and matrix-assisted laser desorption/ionization (MALDI) IMS. Chemical derivatization with 4-hydroxy-3-methoxycinnamaldehyde (CA) was used to improve sensitivity and specificity. CA was applied to the tissue via MALDI sample targets precoated with a mixture of derivatization reagent and ferulic acid (FA) as a MALDI matrix. Spatial distributions of chemically derivatized endogenous metabolites in tissue were determined by high-mass resolution and MSn imaging mass spectrometry. We highlight an analytical strategy for metabolite validation whereby tissue extracts are analyzed by high-performance liquid chromatography (HPLC)-MS/MS to unambiguously identify metabolites and distinguish them from isobaric compounds. PMID:25044893

Was bedeutet Trägheit? Begriff und Wirkung der Trägheit im Rahmen des Wechselverhaltens von Konsumenten im Strommarkt

NARCIS (Netherlands)

Henseler, Jörg

2006-01-01

In Wissenschaft und Praxis wird die Trägheit der Konsumenten als Ursache der geringen Wechselrate im deutschen Strommarkt für Haushaltskunden diskutiert. Der vorliegende Beitrag arbeitet heraus, dass es sich bei dieser Argumentation entweder um eine Tautologie oder ein Synomym für den Verbleib in

Miniature GC-Minicell Ion Mobility Spectrometer (IMS) for In Situ Measurements in Astrobiology Planetary Missions

Science.gov (United States)

Kojiro, Daniel R.; Stimac, Robert M.; Kaye, William J.; Holland, Paul M.; Takeuchi, Norishige

2006-01-01

Astrobiology flight experiments require highly sensitive instrumentation for in situ analysis of volatile chemical species and minerals present in the atmospheres and surfaces of planets, moons, and asteroids. The complex mixtures encountered place a heavy burden on the analytical instrumentation to detect and identify all species present. The use of land rovers and balloon aero-rovers place additional emphasis on miniaturization of the analytical instrumentation. In addition, smaller instruments, using tiny amounts of consumables, allow the use of more instrumentation and/or ionger mission life for stationary landers/laboratories. The miniCometary Ice and Dust Experiment (miniCIDEX), which combined Gas Chromatography (GC) with helium Ion Mobility Spectrometry (IMS), was capable of providing the wide range of analytical information required for Astrobiology missions. The IMS used here was based on the PCP model 111 IMS. A similar system, the Titan Ice and Dust Experiment (TIDE), was proposed as part of the Titan Orbiter Aerorover Mission (TOAM). Newer GC systems employing Micro Electro- Mechanical System (MEMS) based technology have greatly reduced both the size and resource requirements for space GCs. These smaller GCs, as well as the continuing miniaturization of Astrobiology analytical instruments in general, has highlighted the need for smaller, dry helium IMS systems. We describe here the development of a miniature, MEMS GC-IMS system (MEMS GC developed by Thorleaf Research Inc.), employing the MiniCell Ion Mobility Spectrometer (IMS), from Ion Applications Inc., developed through NASA's Astrobiology Science and Technology Instrument Development (ASTID) Program and NASA s Small Business Innovative Research (SBIR) Program.