WorldWideScience

Sample records for intermediate addition policies

  1. The Russian Landing Rate, Central Bank’s Policy Related Rate and Intermediation Premium

    Directory of Open Access Journals (Sweden)

    Chu V. Nguyen

    2017-04-01

    Full Text Available This paper illustrates asymmetries in the Russian intermediation premium as measured by the spread between the commercial lending rate and the Central Bank’s policy related rate. Empirical results have shown that the Russian intermediation premium adjusts to the threshold faster when the Central Bank’s policy related rates increase relative to lending rates as opposed to when the Central Bank’s policy related rates move in the opposite direction. The findings of this paper suggest that during the period when the Russian Federation faced formidable challenges from a sharp decline in oil prices and reduced access to international capital markets due to Western sanctions, the Central Bank of Russia was not effective in utilizing countercyclical monetary policy to achieve macroeconomic objectives and commercial banks exhibited predatory pricing behavior.

  2. 75 FR 33824 - Pharmaceutical Products and Chemical Intermediates, Fourth Review: Advice Concerning the Addition...

    Science.gov (United States)

    2010-06-15

    ... INTERNATIONAL TRADE COMMISSION [Investigation No. 332-520] Pharmaceutical Products and Chemical Intermediates, Fourth Review: Advice Concerning the Addition of Certain Products to the Pharmaceutical Appendix..., Pharmaceutical Products and Chemical Intermediates, Fourth Review: Advice Concerning the Addition of Certain...

  3. Measuring the Impact of Financial Intermediation: Linking Contract Theory to Econometric Policy Evaluation.

    Science.gov (United States)

    Townsend, Robert M; Urzua, Sergio S

    2009-09-01

    We study the impact that financial intermediation can have on productivity through the alleviation of credit constraints in occupation choice and/or an improved allocation of risk, using both static and dynamic structural models as well as reduced form OLS and IV regressions. Our goal in this paper is to bring these two strands of the literature together. Even though, under certain assumptions, IV regressions can recover accurately the true model-generated local average treatment effect, these are quantitatively different, in order of magnitude and even sign, from other policy impact parameters (e.g., ATE and TT). We also show that laying out clearly alternative models can guide the search for instruments. On the other hand adding more margins of decision, i.e., occupation choice and intermediation jointly, or adding more periods with promised utilities as key state variables, as in optimal multi-period contracts, can cause the misinterpretation of IV as the causal effect of interest.

  4. Intermediate evaluation of USAID/Cairo energy policy planning project

    Energy Technology Data Exchange (ETDEWEB)

    Wilbanks, T.J.; Wright, S.B. (Oak Ridge National Lab., TN (United States)); Barron, W.F. (Hong Kong Univ. (Hong Kong)); Kamel, A.M. (Ain Shams Univ., Cairo (Egypt)); Santiago, H.T. (USDOE, Washington, DC (United States))

    1992-01-01

    Three years ago, a team from the Oak Ridge National Laboratory and the Oak Ridge Associated Universities, supplemented by an expert from the US Department of Energy and a senior Egyptian energy professional, carried out what was termed an intermediate evaluation'' of a major energy policy project in Egypt. Supported by USAID/Cairo, the project had concentrated on developing and strengthening an Organization for Energy Planning (OEP) within the Government of India, and it was actually scheduled to end less than a year after this evaluation. The evaluation was submitted to USAID/Cairo and circulated elsewhere in the US Agency for International Development and the Government of Egypt as an internal report. Over the next several years, the USAID energy planning project ended and the functions performed by OEP were merged with planning capabilities in the electric power sector. Now that the major issues addressed by the evaluation report have been resolved, we are making it available to a broader audience as a contribution to the general literature on development project evaluation and institution-building.

  5. Intermediate evaluation of USAID/Cairo energy policy planning project

    Energy Technology Data Exchange (ETDEWEB)

    Wilbanks, T.J.; Wright, S.B. [Oak Ridge National Lab., TN (United States); Barron, W.F. [Hong Kong Univ. (Hong Kong); Kamel, A.M. [Ain Shams Univ., Cairo (Egypt); Santiago, H.T. [USDOE, Washington, DC (United States)

    1992-09-01

    Three years ago, a team from the Oak Ridge National Laboratory and the Oak Ridge Associated Universities, supplemented by an expert from the US Department of Energy and a senior Egyptian energy professional, carried out what was termed an ``intermediate evaluation`` of a major energy policy project in Egypt. Supported by USAID/Cairo, the project had concentrated on developing and strengthening an Organization for Energy Planning (OEP) within the Government of India, and it was actually scheduled to end less than a year after this evaluation. The evaluation was submitted to USAID/Cairo and circulated elsewhere in the US Agency for International Development and the Government of Egypt as an internal report. Over the next several years, the USAID energy planning project ended and the functions performed by OEP were merged with planning capabilities in the electric power sector. Now that the major issues addressed by the evaluation report have been resolved, we are making it available to a broader audience as a contribution to the general literature on development project evaluation and institution-building.

  6. The MHD intermediate shock interaction with an intermediate wave: Are intermediate shocks physical?

    International Nuclear Information System (INIS)

    Wu, C.C.

    1988-01-01

    Contrary to the usual belief that MHD intermediate shocks are extraneous, the authors have recently shown by numerical solutions of dissipative MHD equations that intermediate shocks are admissible and can be formed through nonlinear steepening from a continuous wave. In this paper, he clarifies the differences between the conventional view and the results by studying the interaction of an MHD intermediate shock with an intermediate wave. The study reaffirms his results. In addition, the study shows that there exists a larger class of shocklike solutions in the time-dependent dissiaptive MHD equations than are given by the MHD Rankine-Hugoniot relations. it also suggests a mechanism for forming rotational discontinuities through the interaction of an intermediate shock with an intermediate wave. The results are of importance not only to the MHD shock theory but also to studies such as magnetic field reconnection models

  7. Characteristics of bank financial intermediation in Croatian counties

    Directory of Open Access Journals (Sweden)

    Jakša Krišto

    2015-03-01

    Full Text Available Research on bank financial intermediation in a country’s narrower territorial units is scarce, in both domestic and international literature. Banks are almost the only financial intermediaries in narrower territorial units and their role is substantial, ranging from participating in regional development to the successful running of their own business. Hence, the main objective of this paper is to examine the characteristics of the financial intermediation of banks in the counties of the Republic of Croatia, both through a comparison between their economic development levels and the general presence of financial intermediation, and a more specific analysis of their deposit and credit policies. The article uses hierarchical and non-hierarchical (k-means cluster analyses to identify relatively homogeneous groups of counties based on sets of indicators of: economic environment, financial development and infrastructure and, at a more detailed level, the deposit and credit policies of banks. The research results suggest heterogeneity and diversity of bank policies across the counties and sets of indicators. Differences have been observed between developed and developing counties, as well as in approaches to banks’ deposit and credit policies. The paper’s findings encourage further research into these issues.

  8. The transport implications of regional policies for the disposal of intermediate level radioactive wastes

    International Nuclear Information System (INIS)

    James, I.A.

    1985-09-01

    This report aims to evaluate transport parameters and logistics associated with the disposal of intermediate-level radioactive wastes, as generated by CEGB, SSEB, UKAEA and BNFL. The assumed power scenario is DoE Scheme 3, which approximates to a moderate power generation scenario, with a 15 GWe PWR programme commissioned between 1991 and 2010, existing Magnox and AGR stations are assumed to have a 30 year lifespan. Three transport options are again assumed, namely; road, rail and a hybrid system, as is consistent with previous studies. These three options will be used in investigating regional policies of disposal, initially at the national level and then progressively disaggregating to a system of three regional depositories serving their respective catchment areas. (author)

  9. The Impact of Assessment Policy on Learning: Replacement Exams or Grade Dropping

    Science.gov (United States)

    MacDermott, Raymond J.

    2013-01-01

    Instructors often debate the merits of alternate grading policies such as dropping the lowest exam or offering an additional exam to replace the lowest score. To date, there has been little research conducted on the impact of these policies on performance. In this study, the author investigates student performance in intermediate macroeconomics…

  10. Policy, regulatory and international spects of the disposal of low - and intermediate radioactive waste and other hazardous waste

    International Nuclear Information System (INIS)

    Olivier, J.P.

    1989-01-01

    This paper focuses on the management of low- and intermediate-level radioactive waste. It recalls briefly the technical background and the main features of the regulatory systems adopted by most countries for their radioactive wastes, the respective role of technical and institutional measures contributing to safety, and the influence of international cooperation. A very preliminary attempt is made to draw a parallel with the situation existing for other hazardous wastes, underlying in particular those aspects which seem important in the discussion of management and regulatory policies

  11. Additive Manufacturing in Finland: Recommendations for a Renewed Innovation Policy

    Science.gov (United States)

    Ituarte, Iñigo Flores; Salmi, Mika; Ballardini, Rosa Maria; Tuomi, Jukka; Partanen, Jouni

    The objective of this research is to define an optimal innovation policy and funding strategy to improve Additive Manufacturing (AM) capabilities in Finnish companies. To do so, we present an international review of innovation programs in the area of AM. In addition, the study replied upon a survey prepared to evaluate factors for AM implementation. The ultimate goal is to help in the definition of a national policy strategy in the area of AM based on the characteristics of the Finnish industrial ecosystem. The methodology and data collection method involved defining the taxonomy of Finnish AM industry. The target group of the survey was a population of AM experts, and individuals with knowledge on AM and industrial processes. Overall, the survey revealed that research and innovation activities are well positioned in Finland. In order for future innovation policies to further support developments in the field, we estimated that policy strategies need to generate about 6-8 M€/year in national and EU- funding instruments for AM technology transfer, development, and innovation activities. Efforts should be targeted towards strengthening uses of AM in final production. In fact, only 36% of Finnish respondents declared to use AM for final production, while leading countries in AM use it in average more than 50%. Another area in need of development in Finland is the use of AM high performance materials. Moreover, outsourcing of AM services in Finland is 23 percentage point higher in national and 13 percentage point higher in international outsourcing to service bureaus and suppliers. In this regard, future policies and funding strategies should maintain the created momentum. However, there is a need to acquire high-end research and industrial equipment to stimulate AM integration to the existing production systems. This in the end can trigger the creation of new products, processes and intellectual property, enabling innovation and competitive advantage.

  12. Introducing a new operational policy : the PIS operational policy

    CSIR Research Space (South Africa)

    Pattinson, T

    2009-01-01

    Full Text Available ; No. of Pages 14 Computers and Chemical Engineering xxx (2009) xxx–xxx Contents lists available at ScienceDirect Computers and Chemical Engineering journa l homepage: www.e lsev ier .com/ locate /compchemeng Introducing a new operational policy...), • Finite Intermediate Storage (FIS), • Unlimited Intermediate Storage (UIS), ARTICLE IN PRESSG ModelCACE-3875; No. of Pages 14 2 T. Pattinson, T. Majozi / Computers and Chemical Engineering xxx (2009) xxx–xxx W situatio ationa polic u CI policie...

  13. Information acquisition and financial intermediation

    OpenAIRE

    Boyarchenko, Nina

    2012-01-01

    This paper considers the problem of information acquisition in an intermediated market, where the specialists have access to superior technology for acquiring information. These informational advantages of specialists relative to households lead to disagreement between the two groups, changing the shape of the intermediation-constrained region of the economy and increasing the frequency of periods when the intermediation constraint binds. Acquiring the additional information is, however, cost...

  14. Assessment of the climate commitments and additional mitigation policies of the United States

    Science.gov (United States)

    Greenblatt, Jeffery B.; Wei, Max

    2016-12-01

    Current intended nationally determined contributions (INDCs) are insufficient to meet the Paris Agreement goal of limiting temperature change to between 1.5 and 2.0 °C above pre-industrial levels, so the effectiveness of existing INDCs will be crucial to further progress. Here we assess the likely range of US greenhouse gas (GHG) emissions in 2025 and whether the US’s INDC can be met, on the basis of updated historical and projected estimates. We group US INDC policies into three categories reflecting potential future policies, and model 17 policies across these categories. With all modelled policies included, the upper end of the uncertainty range overlaps with the 2025 INDC target, but the required reductions are not achieved using reference values. Even if all modelled policies are implemented, additional GHG reduction is probably required; we discuss several potential policies.

  15. Basel accord and financial intermediation: The impact of policy

    OpenAIRE

    Berka, Martin; Zimmermann, Christian

    2012-01-01

    This paper studies loan activity in a context where banks must follow Basel Accord-type rules and acquire financing from households. Loan activity typically decreases when entrepreneurs' investment returns decline, and we study which type of policy could reinvigorate an economy in a trough. We find that active monetary policy increases loan volume even when the economy is in good shape; introducing active capital requirement policy can be effective as well if it implies tightening of regulati...

  16. Policy considerations of low-level and intermediate-level radioactive wastes from a public interest perspective

    International Nuclear Information System (INIS)

    Rodgers, S.

    1977-01-01

    A critical, environmentalist view is taken of the problem of low-level radioactive waste disposal. Policy questions and needs for additional data are listed. The lack of a requirement for environmental impact statements prior to site licensing is pointed out. Some of New Mexico's experiences are briefly recounted. The need for definitions for radioactive wastes is pointed out

  17. Language in use intermediate : classroom book

    CERN Document Server

    Doff, Adrian

    1995-01-01

    ach of the four levels comprises about 80 hours of class work, with additional time for the self-study work. The Teacher's Book contains all the pages from the Classroom Book, with interleaved teaching notes including optional activities to cater for different abilities. There is a video to accompany the Beginner, Pre-intermediate and Intermediate levels. Each video contains eight stimulating and entertaining short programmes, as well as a booklet of photocopiable activities. Free test material is available in booklet and web format for Beginner and Pre-intermediate levels. Visit www.cambridge.org/elt/liu or contact your local Cambridge University Press representative.

  18. Language in use intermediate : teacher's book

    CERN Document Server

    Doff, Adrian

    1998-01-01

    Each of the four levels comprises about 80 hours of class work, with additional time for the self-study work. The Teacher's Book contains all the pages from the Classroom Book, with interleaved teaching notes including optional activities to cater for different abilities. There is a video to accompany the Beginner, Pre-intermediate and Intermediate levels. Each video contains eight stimulating and entertaining short programmes, as well as a booklet of photocopiable activities. Free test material is available in booklet and web format for Beginner and Pre-intermediate levels. Visit www.cambridge.org/elt/liu or contact your local Cambridge University Press representative.

  19. Exploring Fiscal Policy at Zero Interest Rates in Intermediate Macroeconomics

    Science.gov (United States)

    Ramamurthy, Srikanth; Sedgley, Norman

    2013-01-01

    Since the financial meltdown of 2007, advanced macroeconomic theory has delved more deeply into the question of the appropriate fiscal policy when the nominal interest rate is close to or at zero percent. Such analysis is typically conducted with the aid of New Keynesian Dynamic Stochastic General Equilibrium models. The policy implications are,…

  20. Language in use intermediate : self-study workbook

    CERN Document Server

    Doff, Adrian

    1994-01-01

    Each of the four levels comprises about 80 hours of class work, with additional time for the self-study work. The Teacher's Book contains all the pages from the Classroom Book, with interleaved teaching notes including optional activities to cater for different abilities. There is a video to accompany the Beginner, Pre-intermediate and Intermediate levels. Each video contains eight stimulating and entertaining short programmes, as well as a booklet of photocopiable activities. Free test material is available in booklet and web format for Beginner and Pre-intermediate levels. Visit www.cambridge.org/elt/liu or contact your local Cambridge University Press representative.

  1. Carbon emission, energy consumption and intermediate goods trade: A regional study of East Asia

    International Nuclear Information System (INIS)

    Zhang, Jingjing

    2015-01-01

    Using country level panel data from East Asia over the period 1998–2011, this paper examines the implications of international production fragmentation-induced intermediate goods trade on the link between energy consumption and carbon pollution. The paper focuses on the interaction effect between energy consumption and trade in intermediate goods on carbon emission. The empirical results presented suggest that international trade in intermediate goods decreases the positive impact on carbon emission of energy consumption. When compared with the trade in final goods, intermediate goods trade contributes to a greater decrease in carbon pollution resulting from energy consumption. These results confirm that the link between energy consumption and carbon pollution in East Asia is significantly affected by international production fragmentation-induced trade in intermediate goods. The results presented in this paper have some important policy implications. - Highlights: • This paper tests the role of intermediates trade in energy-development nexus. • Empirical study is based on data of East Asia. • International trade can reduce the carbon pollution caused by energy use. • Intermediates trade has higher moderating effect than non-intermediate trade.

  2. Formation, structure, and stability of MHD intermediate shocks

    International Nuclear Information System (INIS)

    Wu, C.C.

    1990-01-01

    Contrary to the usual belief that MHD intermediate shocks are extraneous, the author has recently shown by numerical solutions of dissipative MHD equations that intermediate shocks are admissible and can be formed through nonlinear wave steepening from continuous waves. In this paper, the formation, structure and stability of intermediate shocks in dissipative MHD are considered in detail. The differences between the conventional theory and his are pointed out and clarified. He shows that all four types of intermediate shocks can be formed from smooth waves. He also shows that there are free parameters in the structure of the intermediate shocks, and that these parameters are related to the shock stability. In addition, he shows that a rotational discontinuity can not exist with finite width, indicate how this is related to the existence of time-dependent intermediate shocks, and show why the conventional theory is not a good approximation to dissipative MHD solutions whenever there is rotation in magnetic field

  3. Policy and technical considerations for intermediate-level and low-level radioactive waste

    International Nuclear Information System (INIS)

    Anon.

    1977-01-01

    This section has addressed issues, topics, and considerations related to low-level and intermediate-level wastes that are basic to developing and establishing environmental radiation protection criteria for radioactive wastes. Applicability of criteria, criteria considerations for sites, control of radiological impact to the population, and long-term considerations are discussed

  4. Effect of Intermediate Hosts on Emerging Zoonoses.

    Science.gov (United States)

    Cui, Jing-An; Chen, Fangyuan; Fan, Shengjie

    2017-08-01

    Most emerging zoonotic pathogens originate from animals. They can directly infect humans through natural reservoirs or indirectly through intermediate hosts. As a bridge, an intermediate host plays different roles in the transmission of zoonotic pathogens. In this study, we present three types of pathogen transmission to evaluate the effect of intermediate hosts on emerging zoonotic diseases in human epidemics. These types are identified as follows: TYPE 1, pathogen transmission without an intermediate host for comparison; TYPE 2, pathogen transmission with an intermediate host as an amplifier; and TYPE 3, pathogen transmission with an intermediate host as a vessel for genetic variation. In addition, we established three mathematical models to elucidate the mechanisms underlying zoonotic disease transmission according to these three types. Stability analysis indicated that the existence of intermediate hosts increased the difficulty of controlling zoonotic diseases because of more difficult conditions to satisfy for the disease to die out. The human epidemic would die out under the following conditions: TYPE 1: [Formula: see text] and [Formula: see text]; TYPE 2: [Formula: see text], [Formula: see text], and [Formula: see text]; and TYPE 3: [Formula: see text], [Formula: see text], [Formula: see text], and [Formula: see text] Simulation with similar parameters demonstrated that intermediate hosts could change the peak time and number of infected humans during a human epidemic; intermediate hosts also exerted different effects on controlling the prevalence of a human epidemic with natural reservoirs in different periods, which is important in addressing problems in public health. Monitoring and controlling the number of natural reservoirs and intermediate hosts at the right time would successfully manage and prevent the prevalence of emerging zoonoses in humans.

  5. Intermediate report. Base for the Broad Public Discussion on Energy Policy in the Netherlands. Het tussenrapport. Basis voor de Brede Maatschappelijke Discussie

    Energy Technology Data Exchange (ETDEWEB)

    1983-01-01

    The Broad Public Djiscussion on Energy Policy (BMD) in the Netherlands is subdivided in an informative and a discussion stage. This intermediate report gives a summary of the first stage. In Ch. 2 the concept of energy and the utilized unities are discussed. Ch. 3 gives information about the actual energy consumption in the world and in the Netherlands and about the varying estimations for the future energy consumption. In Ch. 4 various possibilities for economization of energy in the Netherlands are discussed. Ch. 5 to 7 give the necessary information about the various energy sources. By source respectively the storages, applications, costs, effects on men and environment and public consequences are under discussion. Ch. 8 presents a comparative summary of the advantages and the drawbacks of various energy sources, the estimations for the future use and possibilities for energy economization. Also some attention is paid to the question on which grounds a choice from the policy possibilities may be based. Ch. 9 and 10 deal with the actual energy policy: how it is realized and what it holds. In Ch. 11 the results are discussed of four scenario-studies: how does the future energy consumption look like under different economical circumstances. What could be the effects of this on the environment at different applications of coal, natural gas, nuclear energy etc.. Furthermore the alternatives, which anounce themselves on the ground of the scenario studies, for the future energy policy are discussed. Finally the discussion questions are presented which following the coordination group will be the centre of interest in the second stage of the BMD. 427 refs.; figs.; tabs.

  6. Lack of benefit for the addition of androgen deprivation therapy to dose-escalated radiotherapy in the treatment of intermediate- and high-risk prostate cancer.

    LENUS (Irish Health Repository)

    Krauss, Daniel

    2012-02-01

    PURPOSE: Assessment of androgen deprivation therapy (ADT) benefits for prostate cancer treated with dose-escalated radiotherapy (RT). METHODS AND MATERIALS: From 1991 to 2004, 1,044 patients with intermediate- (n = 782) or high-risk (n = 262) prostate cancer were treated with dose-escalated RT at William Beaumont Hospital. Patients received external-beam RT (EBRT) alone, brachytherapy (high or low dose rate), or high dose rate brachytherapy plus pelvic EBRT. Intermediate-risk patients had Gleason score 7, prostate-specific antigen (PSA) 10.0-19.9 ng\\/mL, or Stage T2b-T2c. High-risk patients had Gleason score 8-10, PSA >\\/=20, or Stage T3. Patients were additionally divided specifically by Gleason score, presence of palpable disease, and PSA level to further define subgroups benefitting from ADT. RESULTS: Median follow-up was 5 years; 420 patients received ADT + dose-escalated RT, and 624 received dose-escalated RT alone. For all patients, no advantages in any clinical endpoints at 8 years were associated with ADT administration. No differences in any endpoints were associated with ADT administration based on intermediate- vs. high-risk group or RT modality when analyzed separately. Patients with palpable disease plus Gleason >\\/=8 demonstrated improved clinical failure rates and a trend toward improved survival with ADT. Intermediate-risk patients treated with brachytherapy alone had improved biochemical control when ADT was given. CONCLUSION: Benefits of ADT in the setting of dose-escalated RT remain poorly defined. This question must continue to be addressed in prospective study.

  7. Liquidity, Financial Intermediation, and Monetary Policy in a New Monetarist Model

    OpenAIRE

    Williamson, Stephen

    2009-01-01

    A model of monetary exchange with private financial intermediation is constructed. Claims on financial intermedaries of two types are traded in transactions: circulating notes and deposits. There can be a role for the government in supplying liqudity, and level changes in the money supply accomplished through open market operations can be nonneutral. A Friedman rule is suboptimal, due to costs of maintaining the stock of currency. The model is used to address some issues related to current mo...

  8. Assessment of environmental impacts following alternative agricultural policy scenarios.

    Science.gov (United States)

    Bárlund, I; Lehtonen, H; Tattari, S

    2005-01-01

    Abstract Finnish agriculture is likely to undergo major changes in the near and intermediate future. The ifuture policy context can be examined at a general level by strategic scenario building. Computer-based modelling in combination with agricultural policy scenarios can in turn create a basis for the assessments of changes in environmental quality following possible changes in Finnish agriculture. The analysis of economic consequences is based on the DREMFIA model, which is applied to study effects of various agricultural policies on land use, animal production, and farmers' income. The model is suitable for an impact analysis covering an extended time span--here up to the year 2015. The changes in land use, obtained with the DREMFIA model assuming rational economic behaviour, form the basis when evaluating environmental impacts of different agricultural policies. The environmental impact assessment is performed using the field scale nutrient transport model ICECREAM. The modelled variables are nitrogen and phosphorus losses in surface runoff and percolation. In this paper the modelling strategy will be presented and highlighted using two case study catchments with varying environmental conditions and land use as an example. In addition, the paper identifies issues arising when connecting policy scenarios with impact modelling.

  9. Trade Liberalization and Optimal Environmental Policies in Vertical Related Markets

    Directory of Open Access Journals (Sweden)

    Yan-Shu Lin

    2012-12-01

    Full Text Available This paper establishes a symmetric two-country model with vertically related markets. In the downstream market, there is one firm in each country selling a homogeneous good, whose production generates pollution, to its home and the foreign markets a la Brander (1981. In the intermediate good market, there is also one upstream firm in each country, supplying the intermediate good only to its own country’s downstream market. The upstream firms can choose either price or quantity to maximize their profits. With this setting, the paper examines the optimal environmental policy and how it is affected by the tariff on the final good. It is found that, under free trade, the optimal final-good output with imperfect intermediate-good market will have the same output level as that with perfect intermediate-good market after imposing the optimal emission tax. The optimal environmental tax is smaller and the optimal environmental policy is less likely to be a green strategy under trade liberalization if the market structure in the intermediate good market is imperfect than perfect competition. On the other hand, the optimal environmental tax is necessarily higher if the upstream firm chooses price than quantity. Moreover, the optimal environmental policy is less likely to be a green strategy under trade liberalization if the upstream firms choose quantity than price to maximize their profits.

  10. Intermediation by Banks and Economic Growth: A Review of Empirical Evidence

    Directory of Open Access Journals (Sweden)

    Marijana Bađun

    2009-06-01

    Full Text Available This paper provides a review of empirical research on the link between financial intermediation by banks and economic growth. Special attention is paid to the issues of causality, non-linearity, time perspective, financial intermediation proxies, and interaction terms. The review shows that there are still quite a few unresolved issues in empirical research, which causes scepticism towards prioritizing financial sector policies in order to cause economic growth. Progress in the finance and growth literature is slow and researchers seem to go round in circles. A possibly fruitful direction for future empirical research is the relationship between government and banks, especially from the standpoint of political economy.

  11. Partially folded intermediates during trypsinogen denaturation

    Directory of Open Access Journals (Sweden)

    Martins N.F.

    1999-01-01

    Full Text Available The equilibrium unfolding of bovine trypsinogen was studied by circular dichroism, differential spectra and size exclusion HPLC. The change in free energy of denaturation was = 6.99 ± 1.40 kcal/mol for guanidine hydrochloride and = 6.37 ± 0.57 kcal/mol for urea. Satisfactory fits of equilibrium unfolding transitions required a three-state model involving an intermediate in addition to the native and unfolded forms. Size exclusion HPLC allowed the detection of an intermediate population of trypsinogen whose Stokes radii varied from 24.1 ± 0.4 Å to 26.0 ± 0.3 Å for 1.5 M and 2.5 M guanidine hydrochloride, respectively. During urea denaturation, the range of Stokes radii varied from 23.9 ± 0.3 Å to 25.7 ± 0.6 Å for 4.0 M and 6.0 M urea, respectively. Maximal intrinsic fluorescence was observed at about 3.8 M urea with 8-aniline-1-naphthalene sulfonate (ANS binding. These experimental data indicate that the unfolding of bovine trypsinogen is not a simple transition and suggest that the equilibrium intermediate population comprises one intermediate that may be characterized as a molten globule. To obtain further insight by studying intermediates representing different stages of unfolding, we hope to gain a better understanding of the complex interrelations between protein conformation and energetics.

  12. Optimal Monetary Policy Cooperation through State-Independent Contracts with Targets

    DEFF Research Database (Denmark)

    Jensen, Henrik

    2000-01-01

    Simple state-independent monetary institutions are shown to secure optimal cooperative policies in a stochastic, linear-quadratic two-country world with international policy spill-overs and national credibility problems. Institutions characterize delegation to independent central bankers facing...... quadratic performance related contracts punishing or rewarding deviations from primary and intermediate policy targets...

  13. Negotiating comfort in low energy housing: The politics of intermediation

    International Nuclear Information System (INIS)

    Grandclément, Catherine; Karvonen, Andrew; Guy, Simon

    2015-01-01

    Optimising the energy performance of buildings is technically and economically challenging but it also has significant social implications. Maintaining comfortable indoor conditions while reducing energy consumption involves careful design, construction, and management of the built environment and its inhabitants. In this paper, we present findings from the study of a new low energy building for older people in Grenoble, France where conflicts emerged over the simultaneous pursuit of energy efficiency and comfort. The findings contribute to the contemporary literature on the sociotechnical study of buildings and energy use by focusing on intermediation, those activities that associate a technology to end users. Intermediation activities take many forms, and in some cases, can result in the harmonisation or alignment of energy efficiency goals and comfort goals. In other cases, intermediation is unsuccessful, leading to the conventional dichotomy between optimising technical performance and meeting occupant preferences. By highlighting the multiple ways that comfort and energy efficiency is negotiated, we conclude that buildings are provisional achievements that are constantly being intermediated. This suggests that building energy efficiency policies and programmes need to provide opportunities for intermediaries to negotiate the desires and preferences of the multiple stakeholders that are implicated in low energy buildings. -- Highlights: •Energy efficiency and comfort are two possibly contradictory aims of buildings. •We study the pursuit of these aims at the occupation stage of a new building. •Aligning these aims involve negotiating them with occupants. •Intermediation processes are key to such negotiations. •Intermediation processes involve both actors and technical devices

  14. U.S. Theater Nuclear Policy

    International Nuclear Information System (INIS)

    Thompson, J.A.

    1994-01-01

    In the brief period between May 1978 and December 12, 1979, U.S. policy, and the policy of the NATO Alliance, toward theater nuclear forces (TNF) changed dramatically. The consequences of this change now dominate the political agenda in East-West (and West-West) relations. The ultimate outcome of the now renamed intermediate-range nuclear force (INF) debate will have far-reaching consequences for the future of the Atlantic Alliance. How did this issue emerge? Why did the US change its policy? How did it work with its Alliance to change NATO policy? These questions, among others, are now figuring in the debate. The answers to these questions are discussed in detail

  15. 15 CFR 291.6 - Additional requirements; Federal policies and procedures.

    Science.gov (United States)

    2010-01-01

    ... and Foreign Trade NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NIST... requirements; Federal policies and procedures. Recipients and subrecipients are subject to all Federal laws and Federal and Department of Commerce policies, regulations, and procedures applicable to Federal financial...

  16. Intermediate treatments

    Science.gov (United States)

    John R. Jones; Wayne D. Shepperd

    1985-01-01

    Intermediate treatments are those applied after a new stand is successfully established and before the final harvest. These include not only intermediate cuttings - primarily thinning - but also fertilization, irrigation, and protection of the stand from damaging agents.

  17. Learning to Argue with Intermediate Macro Theory: A Semester-Long Team Writing Project

    Science.gov (United States)

    Strasser, Georg; Wolfe, Marketa Halova

    2014-01-01

    The authors describe their experience with integrating a semester-long economic analysis project into an intermediate macroeconomic theory course. Students work in teams of "economic advisors" to write a series of nested reports that analyze the current state of the economy, and propose and evaluate policies for a decision-maker. The…

  18. Distribution planning for a divergent n-echelon network without intermediate stocks under service restrictions

    NARCIS (Netherlands)

    Verrijdt, J.H.C.M.; Kok, de A.G.

    1995-01-01

    In this paper we discuss a periodic review control policy for general N-echelon distribution networks without batch size or capacity constraints. Only stockpoints at the end of the network are allowed to hold stock, whereas the intermediate stockpoints act as pure distribution centers that allocate

  19. Environmental policy on radwaste management and disposal in China

    International Nuclear Information System (INIS)

    Zhao Yamin

    1993-01-01

    This paper introduces the environmental policy on radwaste management and disposal. In order to prevent different kinds of radwaste from polluting environment, ensure public health, and simultaneously promote the development of nuclear energy and nuclear technology, a set of environmental policies on radwaste management and disposal has been established. The major policy are as follows: (1) Solidifying the temporarily-stored radioactive liquid waste as early as possible. (2) Limiting the temporarily-stored time for intermediate-and low-level solidified radwaste, and solid radwaste. (3) Constructing regional disposal repository for Low and Intermediate level radwaste (L/ILW) (4) The radwaste and spent radiation sources arising from nuclear technology application shall be sent to the provincial waste repositories that are named City Radwaste Repository. (5) The radwaste coming from the development and application of inter-grown radioactive mineral resources should be stored in the dams which have to be provided

  20. Isoporphyrin Intermediate in Heme Oxygenase Catalysis

    Science.gov (United States)

    Evans, John P.; Niemevz, Fernando; Buldain, Graciela; de Montellano, Paul Ortiz

    2008-01-01

    Human heme oxygenase-1 (hHO-1) catalyzes the O2- and NADPH-dependent oxidation of heme to biliverdin, CO, and free iron. The first step involves regiospecific insertion of an oxygen atom at the α-meso carbon by a ferric hydroperoxide and is predicted to proceed via an isoporphyrin π-cation intermediate. Here we report spectroscopic detection of a transient intermediate during oxidation by hHO-1 of α-meso-phenylheme-IX, α-meso-(p-methylphenyl)-mesoheme-III, and α-meso-(p-trifluoromethylphenyl)-mesoheme-III. In agreement with previous experiments (Wang, J., Niemevz, F., Lad, L., Huang, L., Alvarez, D. E., Buldain, G., Poulos, T. L., and Ortiz de Montellano, P. R. (2004) J. Biol. Chem. 279, 42593–42604), only the α-biliverdin isomer is produced with concomitant formation of the corresponding benzoic acid. The transient intermediate observed in the NADPH-P450 reductase-catalyzed reaction accumulated when the reaction was supported by H2O2 and exhibited the absorption maxima at 435 and 930 nm characteristic of an isoporphyrin. Product analysis by reversed phase high performance liquid chromatography and liquid chromatography electrospray ionization mass spectrometry of the product generated with H2O2 identified it as an isoporphyrin that, on quenching, decayed to benzoylbiliverdin. In the presence of H218O2, one labeled oxygen atom was incorporated into these products. The hHO-1-isoporphyrin complexes were found to have half-lives of 1.7 and 2.4 h for the p-trifluoromethyl- and p-methyl-substituted phenylhemes, respectively. The addition of NADPH-P450 reductase to the H2O2-generated hHO-1-isoporphyrin complex produced α-biliverdin, confirming its role as a reaction intermediate. Identification of an isoporphyrin intermediate in the catalytic sequence of hHO-1, the first such intermediate observed in hemoprotein catalysis, completes our understanding of the critical first step of heme oxidation. PMID:18487208

  1. [Intermediate energy nuclear physics

    International Nuclear Information System (INIS)

    1989-01-01

    This report summarizes work in experimental Intermediate Energy Nuclear Physics carried out between October 1, 1988 and October 1, 1989 at the Nuclear Physics Laboratory of the University of Colorado, Boulder, under grant DE-FG02-86ER-40269 with the United States Department of Energy. The experimental program is very broadly based, including pion-nucleon studies at TRIUMF, inelastic pion scattering and charge exchange reactions at LAMPF, and nucleon charge exchange at LAMPF/WNR. In addition, a number of other topics related to accelerator physics are described in this report

  2. Prevalence of Cigarette smoking among Intermediate Qatari School Male Students

    International Nuclear Information System (INIS)

    Mossa, Samir Y.; Khan, Zulfaquar A.; Malik, Mariyam A.; Al-Sayed, H.

    2006-01-01

    Attempt was made to find out knowledge, attitudes and practices of Qatari male students and attending four intermediate schools in Doha, about cigarette smoking. 475 boys aged between 12-18 years were the subject of our study. A survey using self-administered questionnaire was carried out into habits, attitudes and knowledge about cigarette smoking. The importance of peer group pressure, parental smoking and early experimentation was confirmed, as was the general awareness of the health hazards of smoking. In contrast, the importance of religion and financial cost of smoking differed markedly. The prevalence of smoking amongst Qatari intermediate schools appears to be considerably less than their counterparts. The results of this research might be used by health planners and policy makers to establish a strategy to prevent smoking as early as possible to reduce morbidity and early mortality and health related economic burden. (author)

  3. Investigation of the O+allyl addition/elimination reaction pathways from the OCH2CHCH2 radical intermediate

    International Nuclear Information System (INIS)

    FitzPatrick, Benjamin L.; Lau, K.-C.; Butler, Laurie J.; Lee, S.-H.; Lin, Jim Jr-Min

    2008-01-01

    These experiments study the preparation of and product channels resulting from OCH 2 CHCH 2 , a key radical intermediate in the O+allyl bimolecular reaction. The data include velocity map imaging and molecular beam scattering results to probe the photolytic generation of the radical intermediate and the subsequent pathways by which the radicals access the energetically allowed product channels of the bimolecular reaction. The photodissociation of epichlorohydrin at 193.3 nm produces chlorine atoms and c-OCH 2 CHCH 2 radicals; these undergo a facile ring opening to the OCH 2 CHCH 2 radical intermediate. State-selective resonance-enhanced multiphoton ionization (REMPI) detection resolves the velocity distributions of ground and spin-orbit excited state chlorine independently, allowing for a more accurate determination of the internal energy distribution of the nascent radicals. We obtain good agreement detecting the velocity distributions of the Cl atoms with REMPI, vacuum ultraviolet (VUV) photoionization at 13.8 eV, and electron bombardment ionization; all show a bimodal distribution of recoil kinetic energies. The dominant high recoil kinetic energy feature peaks near 33 kcal/mol. To elucidate the product channels resulting from the OCH 2 CHCH 2 radical intermediate, the crossed laser-molecular beam experiment uses VUV photoionization and detects the velocity distribution of the possible products. The data identify the three dominant product channels as C 3 H 4 O (acrolein)+H, C 2 H 4 +HCO (formyl radical), and H 2 CO (formaldehyde)+C 2 H 3 . A small signal from C 2 H 2 O (ketene) product is also detected. The measured velocity distributions and relative signal intensities at m/e=27, 28, and 29 at two photoionization energies show that the most exothermic product channel, C 2 H 5 +CO, does not contribute significantly to the product branching. The higher internal energy onset of the acrolein+H product channel is consistent with the relative barriers en route to

  4. Investigation of the O+allyl addition/elimination reaction pathways from the OCH2CHCH2 radical intermediate

    Science.gov (United States)

    Fitzpatrick, Benjamin L.; Lau, Kai-Chung; Butler, Laurie J.; Lee, Shih-Huang; Lin, Jim-Min, Jr.

    2008-08-01

    These experiments study the preparation of and product channels resulting from OCH2CHCH2, a key radical intermediate in the O+allyl bimolecular reaction. The data include velocity map imaging and molecular beam scattering results to probe the photolytic generation of the radical intermediate and the subsequent pathways by which the radicals access the energetically allowed product channels of the bimolecular reaction. The photodissociation of epichlorohydrin at 193.3 nm produces chlorine atoms and c-OCH2CHCH2 radicals; these undergo a facile ring opening to the OCH2CHCH2 radical intermediate. State-selective resonance-enhanced multiphoton ionization (REMPI) detection resolves the velocity distributions of ground and spin-orbit excited state chlorine independently, allowing for a more accurate determination of the internal energy distribution of the nascent radicals. We obtain good agreement detecting the velocity distributions of the Cl atoms with REMPI, vacuum ultraviolet (VUV) photoionization at 13.8 eV, and electron bombardment ionization; all show a bimodal distribution of recoil kinetic energies. The dominant high recoil kinetic energy feature peaks near 33 kcal/mol. To elucidate the product channels resulting from the OCH2CHCH2 radical intermediate, the crossed laser-molecular beam experiment uses VUV photoionization and detects the velocity distribution of the possible products. The data identify the three dominant product channels as C3H4O (acrolein)+H, C2H4+HCO (formyl radical), and H2CO (formaldehyde)+C2H3. A small signal from C2H2O (ketene) product is also detected. The measured velocity distributions and relative signal intensities at m/e=27, 28, and 29 at two photoionization energies show that the most exothermic product channel, C2H5+CO, does not contribute significantly to the product branching. The higher internal energy onset of the acrolein+H product channel is consistent with the relative barriers en route to each of these product channels

  5. Intermediate neutron spectrum problems and the intermediate neutron spectrum experiment

    International Nuclear Information System (INIS)

    Jaegers, P.J.; Sanchez, R.G.

    1996-01-01

    Criticality benchmark data for intermediate energy spectrum systems does not exist. These systems are dominated by scattering and fission events induced by neutrons with energies between 1 eV and 1 MeV. Nuclear data uncertainties have been reported for such systems which can not be resolved without benchmark critical experiments. Intermediate energy spectrum systems have been proposed for the geological disposition of surplus fissile materials. Without the proper benchmarking of the nuclear data in the intermediate energy spectrum, adequate criticality safety margins can not be guaranteed. The Zeus critical experiment now under construction will provide this necessary benchmark data

  6. Spacing Sensitivity Analysis of HLW Intermediate Storage Facility

    International Nuclear Information System (INIS)

    Youn, Bum Soo; Lee, Kwang Ho

    2010-01-01

    Currently, South Korea's spent fuels are stored in its temporary storage within the plant. But the temporary storage is expected to be reaching saturation soon. For the effective management of spent fuel wastes, the need for intermediate storage facility is a desperate position. However, the research for the intermediate storage facility for waste has not made active so far. In addition, in case of foreign countries it is mostly treated confidentially and the information isn't easy to collect. Therefore, the purpose of this study is creating the basic thermal analysis data for the waste storage facility that will be valuable in the future

  7. Changes to the Intermediate Accounting Course Sequence

    Science.gov (United States)

    Davidson, Lesley H.; Francisco, William H.

    2009-01-01

    There is an ever-growing amount of information that must be covered in Intermediate Accounting courses. Due to recent accounting standards and the implementation of IFRS this trend is likely to continue. This report incorporates the results of a recent survey to examine the trend of spending more course time to cover this additional material.…

  8. THE IMPLEMENTATION OF ENGLISH-ONLY POLICY IN THE TERTIARY EFL CONTEXT IN TAIWAN

    Directory of Open Access Journals (Sweden)

    David Dirkwen Wei

    2013-01-01

    Full Text Available Abstract: The implementation of English-only policy in the English classes at Wenzao Ursuline College of Languages in Taiwan has continued for nearly 40 years. Its advantages and disadvantages have also been debated and challenged because of the rising demands on students’ English proficiency in Taiwan. This study intended to reexamine the efficiency of the implementation of English-only policy in the English learning at a college of languages in Taiwan. Both quantitative and qualitative methods were used in the process of data collection. 279 English major and non-English major students were invited to answer questionnaires, and six participants were invited to join interviews. The process of data analysis included the analysis of both the quantitative questionnaire data and the qualitative interview data. This study found students’ progress in English listening and speaking proficiency in the basic and lower-intermediate levels because of English-only policy. However, the interaction between teachers and some students was hampered because of the policy. Also, the ambiguity emerging in the insistence on using English only blocked some learners from comprehending the meanings of the texts they were learning, specifically the texts in the upper-intermediate and intermediate-advanced levels of English reading and writing courses. This study also found that proper tolerance of using both students’ native language and English in TEFL classes in the way of code-switching may help students more than the implementation of English-only policy in a tertiary TEFL context.

  9. Identification and characterization of the intermediate phase in hybrid organic-inorganic MAPbI3 perovskite.

    Science.gov (United States)

    Guo, Xin; McCleese, Christopher; Kolodziej, Charles; Samia, Anna C S; Zhao, Yixin; Burda, Clemens

    2016-03-07

    Perovskite films were prepared using single step solution deposition at different annealing temperatures and annealing times. The crystal structure, phases and grain size were investigated with XRD, XPS and SEM/EDX. The prepared films show a typical orientation of tetragonal perovskite phase and a gradual transition at room temperature from the yellow intermediate phase to the black perovskite phase. Films with high purity were obtained by sintering at 100 °C. In addition, the chemical composition and crystal structure of intermediate phase were investigated in detail. FTIR, UV-vis and NMR spectra revealed the occurance of DMF complexes. Interestingly, the intermediate phase could be transformed to the black perovskite phase upon X-ray irradiation. In addition, the recovery of the aged perovskite films from a yellow intermediate phase back to the black perovskite was shown to be viable via heating and X-ray irradiation.

  10. Intermediality and media change

    OpenAIRE

    2012-01-01

    This book is about intermediality as an approach to analysing and understanding media change. Intermediality and Media Change is critical of technological determinism that characterises 'new media discourse' about the ongoing digitalization, framed as a revolution and creating sharp contrasts between old and new media. Intermediality instead emphasises paying attention to continuities between media of all types and privileges a comparative perspective on technological changes in media over ti...

  11. Intermediate Fragment

    DEFF Research Database (Denmark)

    Kruse Aagaard, Anders

    2015-01-01

    This text and its connected exhibition are aiming to reflect both on the thoughts, the processes and the outcome of the design and production of the artefact ‘Intermediate Fragment’ and making as a contemporary architectural tool in general. Intermediate Fragment was made for the exhibition ‘Enga...... of realising an exhibition object was conceived, but expanded, refined and concretised through this process. The context of the work shown here is an interest in a tighter, deeper connection between experimentally obtained material knowledge and architectural design....

  12. Governance-Default Risk Relationship and the Demand for Intermediated and Non-Intermediated Debt

    Directory of Open Access Journals (Sweden)

    Husam Aldamen

    2012-09-01

    Full Text Available This paper explores the impact of corporate governance on the demand for intermediated debt (asset finance, bank debt, non-bank private debt and non-intermediated debt (public debt in the Australian debt market. Relative to other countries the Australian debt market is characterised by higher proportions of intermediated or private debt with a lower inherent level of information asymmetry in that private lenders have greater access to financial information (Gray, Koh & Tong 2009. Our firm level, cross-sectional evidence suggests that higher corporate governance impacts demand for debt via the mitigation of default risk. However, this relationship is not uniform across all debt types. Intermediated debt such as bank and asset finance debt are more responsive to changes in governance-default risk relationship than non-bank and non-intermediated debt. The implication is that a firm’s demand for different debt types will reflect its governance-default risk profile.

  13. Variational approach to excitation of atomic hydrogen atoms by impacts of protons at intermediate velocities

    International Nuclear Information System (INIS)

    Lasri, B.; Bouamoud, M.; Gayet, R.

    2006-01-01

    A variational approach to the excitation of atoms by ion impacts at intermediate velocities is re-examined. Contributions from intermediate states of the target continuum, that were ignored in previous applications of this approach, are taken into account. With this improved variational approach, excitation cross sections of hydrogen atoms by intermediate energy protons are calculated and compared to recent experimental data and to previous theoretical cross sections. The influence of the intermediate target continuum is found to be very weak. In addition, the present approach is shown to apply as long as the capture process is negligible

  14. Additional renewable energy growth through small-scale community orientated energy policies

    International Nuclear Information System (INIS)

    Hain, J.J.; Ault, G.W.; Galloway, S.J.; Cruden, A.; McDonald, J.R.

    2005-01-01

    This paper summarises the energy policies that the UK Government has enacted in order to achieve its renewable targets by 2010. Current policies are designed primarily to support large-scale renewable projects through Renewable Obligation Certificates, Levy Exemption Certificates and capital grant schemes. Non-profit domestic and non-profit community renewable projects are also eligible for grant support. First-hand experience of privately owned renewable projects indicate that existing renewable policy is insufficient in its support of both small-scale and community-based profit oriented renewable energy (RE) schemes. Primary and secondary survey information suggests that people living in regions where RE will be situated may generally be inclined to support broader uses of renewables in these regions. Small-scale renewables can make a significant cumulative contribution to the RE mix. The results reported in this paper support the contention that the Government could go further towards approaching its targets through rural-focused changes to its energy incentive programmes

  15. Holistic oil field value management: using system dynamics for 'intermediate level' and 'value-based' modelling in the oil industry

    International Nuclear Information System (INIS)

    Corben, D.; Stevenson, R.; Wolstenholme, E.F.

    1999-01-01

    System dynamics has been seen primarily as a strategic tool, most effectively used at the highest level of strategy to identify robust policy interventions under a wide range of scenarios. However, an alternative, complementary and powerful role is emerging. This is at an 'intermediate level' in organisations to coordinate and integrate policies across the value chain. It is at this level where business value, as defined by the discounted value of future free cash flow, is both created and destroyed. This paper introduces the need for 'intermediate-level' and 'value-based' modelling and emphasises the natural role of system dynamics in supporting a methodology to fulfil the need. It describes the development of an approach and its application in the oil industry to coordinate the response of people and tools within operational, financial and commercial functions across the value chain to address a variety of problems and issues. (author)

  16. Norwegian work on establishing a combined storage and disposal facility for low and intermediate level waste

    International Nuclear Information System (INIS)

    International Atomic Energy Agency WATRP Review Team.

    1995-12-01

    The IAEA has, through its Waste Management Assessment and Technical Review Programme (WATRP), evaluated policies and facilities related to management of radioactive waste in Norway. It is concluded that the Himdalen site, in combination with the chosen engineering concept, can be suitable for the storage and disposal of the relatively small amounts of Norwegian low and intermediate level waste

  17. MHD intermediate shock discontinuities: Pt. 1

    International Nuclear Information System (INIS)

    Kennel, C.F.; Blandford, R.D.; Coppi, P.

    1989-01-01

    Recent numerical investigations have focused attention once more on the role of intermediate shocks in MHD. Four types of intermediate shock are identified using a graphical representation of the MHD Rankine-Hugoniot conditions. This same representation can be used to exhibit the close relationship of intermediate shocks to switch-on shocks and rotational discontinuities. The conditions under which intermediate discontinuities can be found are elucidated. The variations in velocity, pressure, entropy and magnetic-field jumps with upstream parameters in intermediate shocks are exhibited graphically. The evolutionary arguments traditionally advanced against intermediate shocks may fail because the equations of classical MHD are not strictly hyperbolic. (author)

  18. Directed Technical Change and Economic Growth Effects of Environmental Policy

    DEFF Research Database (Denmark)

    Kruse-Andersen, Peter Kjær

    2016-01-01

    A Schumpeterian growth model is developed to investigate how environmental policy affects economic growth when environmental policy also affects the direction of technical change. In contrast to previous models, production and pollution abatement technologies are embodied in separate intermediate...... unambiguously directs research efforts toward pollution abatement technologies and away from production technologies. This directed technical change reduces economic growth and pollution emission growth. Simulation results indicate that even large environmental policy reforms have small economic growth effects....... However, these economic growth effects have relatively large welfare effects which suggest that static models and exogenous growth models leave out an important welfare effect of environmental policy....

  19. The implications of probabilistic risk assessment for safety policy

    International Nuclear Information System (INIS)

    Hayns, M.R.

    1987-01-01

    The use of PRA results in decision making requires a level of understanding on the part of the decision maker which is higher than that obtaining previously. The most important application of PRA lies not in the final results but in the intermediate results which refer to specific systems and operations. Such intermediate results are of great value either at the design stage or later during operation. One of the most 'visible' uses of PRA results is in comparing calculated plant risks with either proposed acceptability criteria, or with other plant, or even natural events. The capability to perform PRA has been established. Only the incorporation of PRA into the licensing process is lacking. The principal conclusions on the implications of PRA for safety policy are as follows: regardless of its state of development, PRA is the only means available for calculating public risk, being able to quantify risk is important in policy related to risk acceptability and to national energy policy. PRAs will be used to establish research and development priorities. Any hazardous plant can be treated using the same methods. More sophisticated methods will be used for solving engineering problems. (author)

  20. How much monetary policy rules do we need to estimate DSGE model for Russia?

    OpenAIRE

    Shulgin, Andrei

    2014-01-01

    This paper presents a three-sector DSGE model for a small open economy under the intermediate exchange rate regime. The central bank balance sheet equations are added to allow introducing two different monetary policy rules in the model. The principal question is how many independent monetary policy rules we need to describe Russian monetary policy in 2001–2012. To get an answer we perform Bayesian estimation of the DSGE model for four different combinations of monetary policy rules. The main...

  1. Evaluation of Different Power of Near Addition in Two Different Multifocal Intraocular Lenses

    Directory of Open Access Journals (Sweden)

    Ugur Unsal

    2016-01-01

    Full Text Available Purpose. To compare near, intermediate, and distance vision and quality of vision, when refractive rotational multifocal intraocular lenses with 3.0 diopters or diffractive multifocal intraocular lenses with 2.5 diopters near addition are implanted. Methods. 41 eyes of 41 patients in whom rotational +3.0 diopters near addition IOLs were implanted and 30 eyes of 30 patients in whom diffractive +2.5 diopters near addition IOLs were implanted after cataract surgery were reviewed. Uncorrected and corrected distance visual acuity, intermediate visual acuity, near visual acuity, and patient satisfaction were evaluated 6 months later. Results. The corrected and uncorrected distance visual acuity were the same between both groups (p=0.50 and p=0.509, resp.. The uncorrected intermediate and corrected intermediate and near vision acuities were better in the +2.5 near vision added intraocular lens implanted group (p=0.049, p=0.005, and p=0.001, resp. and the uncorrected near vision acuity was better in the +3.0 near vision added intraocular lens implanted group (p=0.001. The patient satisfactions of both groups were similar. Conclusion. The +2.5 diopters near addition could be a better choice in younger patients with more distance and intermediate visual requirements (driving, outdoor activities, whereas the + 3.0 diopters should be considered for patients with more near vision correction (reading.

  2. Unraveling the structure and chemical mechanisms of highly oxygenated intermediates in oxidation of organic compounds

    KAUST Repository

    Wang, Zhandong

    2017-11-28

    Decades of research on the autooxidation of organic compounds have provided fundamental and practical insights into these processes; however, the structure of many key autooxidation intermediates and the reactions leading to their formation still remain unclear. This work provides additional experimental evidence that highly oxygenated intermediates with one or more hydroperoxy groups are prevalent in the autooxidation of various oxygenated (e.g., alcohol, aldehyde, keto compounds, ether, and ester) and nonoxygenated (e.g., normal alkane, branched alkane, and cycloalkane) organic compounds. These findings improve our understanding of autooxidation reaction mechanisms that are routinely used to predict fuel ignition and oxidative stability of liquid hydrocarbons, while also providing insights relevant to the formation mechanisms of tropospheric aerosol building blocks. The direct observation of highly oxygenated intermediates for the autooxidation of alkanes at 500–600 K builds upon prior observations made in atmospheric conditions for the autooxidation of terpenes and other unsaturated hydrocarbons; it shows that highly oxygenated intermediates are stable at conditions above room temperature. These results further reveal that highly oxygenated intermediates are not only accessible by chemical activation but also by thermal activation. Theoretical calculations on H-atom migration reactions are presented to rationalize the relationship between the organic compound’s molecular structure (n-alkane, branched alkane, and cycloalkane) and its propensity to produce highly oxygenated intermediates via extensive autooxidation of hydroperoxyalkylperoxy radicals. Finally, detailed chemical kinetic simulations demonstrate the influence of these additional reaction pathways on the ignition of practical fuels.

  3. Unraveling the structure and chemical mechanisms of highly oxygenated intermediates in oxidation of organic compounds

    KAUST Repository

    Wang, Zhandong; Popolan-Vaida, Denisia M.; Chen, Bingjie; Moshammer, Kai; Mohamed, Samah; Wang, Heng; Sioud, Salim; Raji, Misjudeen; Kohse-Hö inghaus, Katharina; Hansen, Nils; Dagaut, Philippe; Leone, Stephen R.; Sarathy, Mani

    2017-01-01

    Decades of research on the autooxidation of organic compounds have provided fundamental and practical insights into these processes; however, the structure of many key autooxidation intermediates and the reactions leading to their formation still remain unclear. This work provides additional experimental evidence that highly oxygenated intermediates with one or more hydroperoxy groups are prevalent in the autooxidation of various oxygenated (e.g., alcohol, aldehyde, keto compounds, ether, and ester) and nonoxygenated (e.g., normal alkane, branched alkane, and cycloalkane) organic compounds. These findings improve our understanding of autooxidation reaction mechanisms that are routinely used to predict fuel ignition and oxidative stability of liquid hydrocarbons, while also providing insights relevant to the formation mechanisms of tropospheric aerosol building blocks. The direct observation of highly oxygenated intermediates for the autooxidation of alkanes at 500–600 K builds upon prior observations made in atmospheric conditions for the autooxidation of terpenes and other unsaturated hydrocarbons; it shows that highly oxygenated intermediates are stable at conditions above room temperature. These results further reveal that highly oxygenated intermediates are not only accessible by chemical activation but also by thermal activation. Theoretical calculations on H-atom migration reactions are presented to rationalize the relationship between the organic compound’s molecular structure (n-alkane, branched alkane, and cycloalkane) and its propensity to produce highly oxygenated intermediates via extensive autooxidation of hydroperoxyalkylperoxy radicals. Finally, detailed chemical kinetic simulations demonstrate the influence of these additional reaction pathways on the ignition of practical fuels.

  4. Is Androgen Deprivation Therapy Necessary in All Intermediate-Risk Prostate Cancer Patients Treated in the Dose Escalation Era?

    International Nuclear Information System (INIS)

    Castle, Katherine O.; Hoffman, Karen E.; Levy, Lawrence B.; Lee, Andrew K.; Choi, Seungtaek; Nguyen, Quynh N.; Frank, Steven J.; Pugh, Thomas J.; McGuire, Sean E.; Kuban, Deborah A.

    2013-01-01

    Purpose: The benefit of adding androgen deprivation therapy (ADT) to dose-escalated radiation therapy (RT) for men with intermediate-risk prostate cancer is unclear; therefore, we assessed the impact of adding ADT to dose-escalated RT on freedom from failure (FFF). Methods: Three groups of men treated with intensity modulated RT or 3-dimensional conformal RT (75.6-78 Gy) from 1993-2008 for prostate cancer were categorized as (1) 326 intermediate-risk patients treated with RT alone, (2) 218 intermediate-risk patients treated with RT and ≤6 months of ADT, and (3) 274 low-risk patients treated with definitive RT. Median follow-up was 58 months. Recursive partitioning analysis based on FFF using Gleason score (GS), T stage, and pretreatment PSA concentration was applied to the intermediate-risk patients treated with RT alone. The Kaplan-Meier method was used to estimate 5-year FFF. Results: Based on recursive partitioning analysis, intermediate-risk patients treated with RT alone were divided into 3 prognostic groups: (1) 188 favorable patients: GS 6, ≤T2b or GS 3+4, ≤T1c; (2) 71 marginal patients: GS 3+4, T2a-b; and (3) 68 unfavorable patients: GS 4+3 or T2c disease. Hazard ratios (HR) for recurrence in each group were 1.0, 2.1, and 4.6, respectively. When intermediate-risk patients treated with RT alone were compared to intermediate-risk patients treated with RT and ADT, the greatest benefit from ADT was seen for the unfavorable intermediate-risk patients (FFF, 74% vs 94%, respectively; P=.005). Favorable intermediate-risk patients had no significant benefit from the addition of ADT to RT (FFF, 94% vs 95%, respectively; P=.85), and FFF for favorable intermediate-risk patients treated with RT alone approached that of low-risk patients treated with RT alone (98%). Conclusions: Patients with favorable intermediate-risk prostate cancer did not benefit from the addition of ADT to dose-escalated RT, and their FFF was nearly as good as patients with low-risk disease

  5. Fiscal deficits, financial fragility, and the effectiveness of government policies

    NARCIS (Netherlands)

    Kirchner, M.; van Wijnbergen, S.

    2012-01-01

    Recent macro developments in the euro area have highlighted the interactions between fiscal policy, sovereign debt, and financial fragility. We take a structural macroeconomic model with frictions in the financial intermediation process, in line with recent research, but introduce asset choice and

  6. Survival outcome of intermediate risk neuroblastoma at Children Cancer Hospital Egypt

    Directory of Open Access Journals (Sweden)

    Hossam Elzomor

    2018-03-01

    Conclusion: A very high rate of survival is currently achievable in patients with intermediate risk neuroblastoma by chemotherapy or chemotherapy and surgery. In addition to response, our plan is to adopt biologically-based treatment to reduce treatment-induced complications among survivors.

  7. Influence of an Intermediate Option on the Description-Experience Gap and Information Search

    OpenAIRE

    Neha Sharma; Shoubhik Debnath; Varun Dutt

    2018-01-01

    Research shows that people tend to overweight small probabilities in description and underweight them in experience, thereby leading to a different pattern of choices between description and experience; a phenomenon known as the Description-Experience (DE) gap. However, little is known on how the addition of an intermediate option and contextual framing influences the DE gap and people’s search strategies. This paper tests the effects of an intermediate option and contextual framing on the DE...

  8. Inoculation Policies in Response to BW Attacks: Additional Factors to Consider

    International Nuclear Information System (INIS)

    Leitner, P. M.

    2007-01-01

    When viewed on its own merits, the debate over who should be inoculated during a period of biological emergency is a rather straightforward public policy decision. The classic public policy 'balancing act' decision-making model is defaulted to as issues of fairness, efficiency, cost-effectiveness, adequacy of supply, mission performance, and constituencies are arrayed and adjudicated. This mainstream approach is appropriate as far as it goes but it also exemplifies a series of structural and perceptual weaknesses when applied to wartime or localized terrorism scenarios. In fact, the establishment of a vaccination policy appropriate to a flu pandemic falls squarely within this mainstream debate. Although the notion of a pandemic carries an assumption of a great many fatalities it does not possess the fear quotient, uncertainty, horror, unnaturalness, or inevitability of a bio-terror or biological warfare incident. As a result, the reliability and responsiveness of key personnel responding to a flu pandemic should be less of an issue than it will be in the event of an intentional man-made biological incident. The principal policy weakness in instances an intentional bio-attack stems from a generalized failure, or refusal, to systematically study the behavior of key personnel, first-responders, soldiers, or critical senior leadership during severe crises occurring in their own backyards. In other words, when the 'balloon goes up' how many of your responders and critical personnel will show up for work? This presentation considers many of the 'unaddressed' factors that experience has shown may have a determinative effect upon the efficacy of a response to a biological incident. Lessons are drawn from experiences of US forces station in the former West Germany, US Defense Department Continuity of Operations Programs, Hurricane Katrina, and the 9/11 attacks on the United States. (author)

  9. The Realization Mechanism of China's Monetary Policy Objectives: 2001-2010

    Institute of Scientific and Technical Information of China (English)

    Wang Guogang

    2013-01-01

    This article explores the realization mechanism for the final and interim targets of China's monetary policy from 2001 to 2010.It finds that the three significant price surges in the ten years were not the results of loose monetary policy While maintaining rapid economic growth,China avoided the inflation linked with excess monetary supply.The introduction of total new lending in the interim targets also showed the maturing of China's monetary policy target system.To improve China's monetary operation,three measures need to te taken:firstly,basing stabilizing monetary policy on the trend of the non-food price index within the CPI;secondly,readjusting the definition of money according the different characteristics of transaction money and reserve money;and thirdly,including yuan exchange rates into the intermediate objectives of monetary policy.

  10. Discourses and Models of Intermediality

    OpenAIRE

    Schröter, Jens

    2011-01-01

    In his article "Discourses and Models of Intermediality" Jens Schröter discusses the question as to what relations do different discourses pose between different "media." Schröter identifies four models of discourse: 1) synthetic intermediality: a "fusion" of different media to super-media, a model with roots in the Wagnerian concept of Gesamtkunstwerk with political connotations, 2) formal (or transmedial) intermediality: a concept based on formal structures not "specific" to one medium but ...

  11. Financial Plumbing and Monetary Policy

    OpenAIRE

    Manmohan Singh

    2014-01-01

    This paper focuses on how changes in financial plumbing of the markets may impact the monetary policy options as central banks contemplate lift off from zero lower bound (ZLB). Under the proposed regulations, banks will face leverage ratio constraints. As a result of quantitative easing (QE), banks want balance sheet “space” for financial intermediation/ non-depository activities. At the same time, regulatory changes are boosting demand for high quality liquid assets. The paper also discusses...

  12. Influence of an Intermediate Option on the Description-Experience Gap and Information Search.

    Science.gov (United States)

    Sharma, Neha; Debnath, Shoubhik; Dutt, Varun

    2018-01-01

    Research shows that people tend to overweight small probabilities in description and underweight them in experience, thereby leading to a different pattern of choices between description and experience; a phenomenon known as the Description-Experience (DE) gap. However, little is known on how the addition of an intermediate option and contextual framing influences the DE gap and people's search strategies. This paper tests the effects of an intermediate option and contextual framing on the DE gap and people's search strategies, where problems require search for information before a consequential choice. In the first experiment, 120 participants made choice decisions across investment problems that differed in the absence or presence of an intermediate option. Results showed that adding an intermediate option did not reduce the DE gap on the maximizing option across a majority of problems. There were a large majority of choices for the intermediate option. Furthermore, there was an increase in switching between options due to the presence of the intermediate option. In the second experiment, 160 participants made choice decisions in problems like those presented in experiment 1; however, problems lacked the investment framing. Results replicated findings from the first experiment and showed a similar DE gap on the maximizing option in a majority of problems in both the absence and presence of the intermediate option. Again, there were a large majority of choices for the intermediate option. Also, there was an increase in switching between options due to the presence of the intermediate option. Meta-analyses revealed that the absence or presence of the intermediate option created certain differences in the strength of frequency and recency processes. Also, a single natural-mean heuristic model was able to account for the experimental results across both experiments. We discuss implications of our findings to consequential decisions made after information search.

  13. Influence of an Intermediate Option on the Description-Experience Gap and Information Search

    Directory of Open Access Journals (Sweden)

    Neha Sharma

    2018-03-01

    Full Text Available Research shows that people tend to overweight small probabilities in description and underweight them in experience, thereby leading to a different pattern of choices between description and experience; a phenomenon known as the Description-Experience (DE gap. However, little is known on how the addition of an intermediate option and contextual framing influences the DE gap and people’s search strategies. This paper tests the effects of an intermediate option and contextual framing on the DE gap and people’s search strategies, where problems require search for information before a consequential choice. In the first experiment, 120 participants made choice decisions across investment problems that differed in the absence or presence of an intermediate option. Results showed that adding an intermediate option did not reduce the DE gap on the maximizing option across a majority of problems. There were a large majority of choices for the intermediate option. Furthermore, there was an increase in switching between options due to the presence of the intermediate option. In the second experiment, 160 participants made choice decisions in problems like those presented in experiment 1; however, problems lacked the investment framing. Results replicated findings from the first experiment and showed a similar DE gap on the maximizing option in a majority of problems in both the absence and presence of the intermediate option. Again, there were a large majority of choices for the intermediate option. Also, there was an increase in switching between options due to the presence of the intermediate option. Meta-analyses revealed that the absence or presence of the intermediate option created certain differences in the strength of frequency and recency processes. Also, a single natural-mean heuristic model was able to account for the experimental results across both experiments. We discuss implications of our findings to consequential decisions made after

  14. Time-resolved resonance Raman spectroscopy of intermediates of bacteriorhodopsin: The bK(590) intermediate.

    Science.gov (United States)

    Terner, J; Hsieh, C L; Burns, A R; El-Sayed, M A

    1979-07-01

    We have combined microbeam and flow techniques with computer subtraction methods to obtain the resonance Raman spectrum of the short lived batho-intermediate (bK(590)) of bacteriorhodopsin. Comparison of the spectra obtained in (1)H(2)O and (2)H(2)O, as well as the fact that the bK(590) intermediate shows large optical red shifts, suggests that the Schiff base linkage of this intermediate is protonated. The fingerprint region of the spectrum of bK(590), sensitive to the isomeric configuration of the retinal chromophore, does not resemble the corresponding region of the parent bR(570) form. The resonance Raman spectrum of bK(590) as well as the spectra of all of the other main intermediates in the photoreaction cycle of bacteriorhodopsin are discussed and compared with resonance Raman spectra of published model compounds.

  15. Role of Intermediate Filaments in Vesicular Traffic

    Directory of Open Access Journals (Sweden)

    Azzurra Margiotta

    2016-04-01

    Full Text Available Intermediate filaments are an important component of the cellular cytoskeleton. The first established role attributed to intermediate filaments was the mechanical support to cells. However, it is now clear that intermediate filaments have many different roles affecting a variety of other biological functions, such as the organization of microtubules and microfilaments, the regulation of nuclear structure and activity, the control of cell cycle and the regulation of signal transduction pathways. Furthermore, a number of intermediate filament proteins have been involved in the acquisition of tumorigenic properties. Over the last years, a strong involvement of intermediate filament proteins in the regulation of several aspects of intracellular trafficking has strongly emerged. Here, we review the functions of intermediate filaments proteins focusing mainly on the recent knowledge gained from the discovery that intermediate filaments associate with key proteins of the vesicular membrane transport machinery. In particular, we analyze the current understanding of the contribution of intermediate filaments to the endocytic pathway.

  16. Intermediality: Bridge to Critical Media Literacy.

    Science.gov (United States)

    Pailliotet, Ann Watts; Semali, Ladislaus; Rodenberg, Rita K.; Giles, Jackie K.; Macaul, Sherry L.

    2000-01-01

    Defines "intermediality" as the ability to critically read and write with and across varied symbol systems. Relates it to critical media literacy. Offers rationales for teaching critical media literacy in general, and intermedial instruction in particular. Identifies seven guiding intermedial elements: theory, texts, processes, contexts,…

  17. The Use of E-Dictionary to Read E-Text by Intermediate and Advanced Learners of Chinese

    Science.gov (United States)

    Wang, Jing

    2012-01-01

    This study focuses on the pedagogical outcomes connected with the use of an e-dictionary by intermediate and advanced learners of Chinese to aid in reading an expository Chinese e-text. Twenty intermediate and advanced participants read an e-text twice aided by an e-dictionary and wrote recalls of the text in English. In addition to low frequency…

  18. Border dimension of Chilean foreign policies: Immobility and urgency of new dynamics

    Directory of Open Access Journals (Sweden)

    Cristian Ovando Santana

    2011-07-01

    Full Text Available The following article draws the priorities of border public policy that define the Chilean foreign policy. Through a theoretical framework from the rational–reflective approach of International Relations, we argue that despite of the increasing openness, internationalization of the country, and the emergence of new actors and subnational initiatives; the views and options between the actors of this new area and the definitions of foreign policy not always match. We propose the need to establish mechanisms that settle the positions among regional social–political actors, intermediate agencies and the central level.

  19. Effects of addition of hydrocolloids on the textural and structural properties of high-protein intermediate moisture food model systems containing sodium caseinate.

    Science.gov (United States)

    Li, J; Wu, Y; Ma, Y; Lu, N; Regenstein, J M; Zhou, P

    2017-08-01

    High-protein intermediate moisture food (HPIMF) containing sodium caseinate (NaCN) often gave a harder texture compared with that made from whey proteins or soy proteins, due to the aggregation of protein particles. The objectives of this study were to explore whether the addition of hydrocolloids could soften the texture and illustrate the possible mechanism. Three kinds of hydrocolloids, xanthan gum, κ-carrageenan, and gum arabic were chosen, and samples including of these three kinds of hydrocolloids were studied through texture analysis using a TPA test and microstructure observation by confocal laser scanning microscopy (CLSM) and scanning electron microscopy (SEM). The texture analysis results showed that xanthan gum was more effective at softening the HPIMF containing NaCN compared to κ-carrageenan and gum arabic. In addition, with the increase of xanthan gum concentration from 0.2 to 2%, the HPIMF matrix became softer, and fractures were observed during the compression for samples with xanthan gum added at low concentrations but not 2%. Microstructure observation suggested that the matrix originally dominated by the network formed through the aggregation of swollen protein particles was inhibited by the addition of xanthan gum, resulting in the softening of the texture and also contributing to the fracture during compression. With the increase of xanthan gum concentration up to 2%, the protein dominating network would be gradually replaced with a matrix dominated by the newly formed network of xanthan gum with protein particles as fillers. Furthermore, this formation of a xanthan gum dominating network structure also resulted in changes in small molecule distribution, as observed using low-field NMR.

  20. Intermediate Ethanol Blends Catalyst Durability Program

    Energy Technology Data Exchange (ETDEWEB)

    West, Brian H; Sluder, Scott; Knoll, Keith; Orban, John; Feng, Jingyu

    2012-02-01

    In the summer of 2007, the U.S. Department of Energy (DOE) initiated a test program to evaluate the potential impacts of intermediate ethanol blends (also known as mid-level blends) on legacy vehicles and other engines. The purpose of the test program was to develop information important to assessing the viability of using intermediate blends as a contributor to meeting national goals for the use of renewable fuels. Through a wide range of experimental activities, DOE is evaluating the effects of E15 and E20 - gasoline blended with 15% and 20% ethanol - on tailpipe and evaporative emissions, catalyst and engine durability, vehicle driveability, engine operability, and vehicle and engine materials. This report provides the results of the catalyst durability study, a substantial part of the overall test program. Results from additional projects will be reported separately. The principal purpose of the catalyst durability study was to investigate the effects of adding up to 20% ethanol to gasoline on the durability of catalysts and other aspects of the emissions control systems of vehicles. Section 1 provides further information about the purpose and context of the study. Section 2 describes the experimental approach for the test program, including vehicle selection, aging and emissions test cycle, fuel selection, and data handling and analysis. Section 3 summarizes the effects of the ethanol blends on emissions and fuel economy of the test vehicles. Section 4 summarizes notable unscheduled maintenance and testing issues experienced during the program. The appendixes provide additional detail about the statistical models used in the analysis, detailed statistical analyses, and detailed vehicle specifications.

  1. Electron-atom scattering at intermediate energies

    International Nuclear Information System (INIS)

    Kingston, A.E.; Walters, H.R.J.

    1982-01-01

    The problems of intermediate energy scattering are approached from the low and high energy ends. At low intermediate energies difficulties associated with the use of pseudostates and correlation terms are discussed, special consideration being given to nonphysical pseudoresonances. Perturbation methods appropriate to high intermediate energies are described and attempts to extend these high energy approximations down to low intermediate energies are studied. It is shown how the importance of electron exchange effects develops with decreasing energy. The problem of assessing the 'effective completeness' of pseudostate sets at intermediate energies is mentioned and an instructive analysis of a 2p pseudostate approximation to elastic e - -H scattering is given. It is suggested that at low energies the Pauli Exclusion Principle can act to hide short range defects in pseudostate approximations. (author)

  2. The intermediate state in Patd

    African Journals Online (AJOL)

    ) Jesus had assumed. (concerning the 'intermediate state') as existing, anything which does not exist. Three basic things about the intermediate state emerge from the parable: (a) Jesus recognizes that at the moment of death, in ipso articulo.

  3. Stabilizing intermediate-term medium-range earthquake predictions

    International Nuclear Information System (INIS)

    Kossobokov, V.G.; Romashkova, L.L.; Panza, G.F.; Peresan, A.

    2001-12-01

    A new scheme for the application of the intermediate-term medium-range earthquake prediction algorithm M8 is proposed. The scheme accounts for the natural distribution of seismic activity, eliminates the subjectivity in the positioning of the areas of investigation and provides additional stability of the predictions with respect to the original variant. According to the retroactive testing in Italy and adjacent regions, this improvement is achieved without any significant change of the alarm volume in comparison with the results published so far. (author)

  4. Higher order antibunching in intermediate states

    International Nuclear Information System (INIS)

    Verma, Amit; Sharma, Navneet K.; Pathak, Anirban

    2008-01-01

    Since the introduction of binomial state as an intermediate state, different intermediate states have been proposed. Different nonclassical effects have also been reported in these intermediate states. But till now higher order antibunching is predicted in only one type of intermediate state, which is known as shadowed negative binomial state. Recently we have shown that the higher order antibunching is not a rare phenomenon [P. Gupta, P. Pandey, A. Pathak, J. Phys. B 39 (2006) 1137]. To establish our earlier claim further, here we have shown that the higher order antibunching can be seen in different intermediate states, such as binomial state, reciprocal binomial state, hypergeometric state, generalized binomial state, negative binomial state and photon added coherent state. We have studied the possibility of observing the higher order subpoissonian photon statistics in different limits of intermediate states. The effects of different control parameters on the depth of non classicality have also been studied in this connection and it has been shown that the depth of nonclassicality can be tuned by controlling various physical parameters

  5. Environmental effects of additional uranium development required by a non-proliferation policy

    International Nuclear Information System (INIS)

    Baca, T.E.; Scudella, G.

    1978-01-01

    New Mexico can expect to see an accelerated development of its uranium resources. The President's policy on non-proliferation will impact the degree and quantity of uranium ore mined. Environmental impacts are significant and are affected by the mining and milling phase more than any other aspect of the uranium fuel cycle. The state has begun evaluating the resource-associated impacts of uranium mining and milling, although very little reliable data are available. The information gathered, however, shows a need for state and Federal evaluation of both the impacts and the non-proliferation policy. 4 references

  6. [Therapy of intermediate uveitis].

    Science.gov (United States)

    Doycheva, D; Deuter, C; Zierhut, M

    2014-12-01

    Intermediate uveitis is a form of intraocular inflammation in which the vitreous body is the major site of inflammation. Intermediate uveitis is primarily treated medicinally and systemic corticosteroids are the mainstay of therapy. When recurrence of uveitis or side effects occur during corticosteroid therapy an immunosuppressive treatment is required. Cyclosporine A is the only immunosuppressive agent that is approved for therapy of uveitis in Germany; however, other immunosuppressive drugs have also been shown to be effective and well-tolerated in patients with intermediate uveitis. In severe therapy-refractory cases when conventional immunosuppressive therapy has failed, biologics can be used. In patients with unilateral uveitis or when the systemic therapy is contraindicated because of side effects, an intravitreal steroid treatment can be carried out. In certain cases a vitrectomy may be used.

  7. Covalent functionalization of graphene with reactive intermediates.

    Science.gov (United States)

    Park, Jaehyeung; Yan, Mingdi

    2013-01-15

    Graphene, a material made exclusively of sp(2) carbon atoms with its π electrons delocalized over the entire 2D network, is somewhat chemically inert. Covalent functionalization can enhance graphene's properties including opening its band gap, tuning conductivity, and improving solubility and stability. Covalent functionalization of pristine graphene typically requires reactive species that can form covalent adducts with the sp(2) carbon structures in graphene. In this Account, we describe graphene functionalization reactions using reactive intermediates of radicals, nitrenes, carbenes, and arynes. These reactive species covalently modify graphene through free radical addition, CH insertion, or cycloaddition reactions. Free radical additions are among the most common reaction, and these radicals can be generated from diazonium salts and benzoyl peroxide. Electron transfer from graphene to aryl diazonium ion or photoactivation of benzoyl peroxide yields aryl radicals that subsequently add to graphene to form covalent adducts. Nitrenes, electron-deficient species generated by thermal or photochemical activation of organic azides, can functionalize graphene very efficiently. Because perfluorophenyl nitrenes show enhanced bimolecular reactions compared with alkyl or phenyl nitrenes, perfluorophenyl azides are especially effective. Carbenes are used less frequently than nitrenes, but they undergo CH insertion and C═C cycloaddition reactions with graphene. In addition, arynes can serve as a dienophile in a Diels-Alder type reaction with graphene. Further study is needed to understand and exploit the chemistry of graphene. The generation of highly reactive intermediates in these reactions leads to side products that complicate the product composition and analysis. Fundamental questions remain about the reactivity and regioselectivity of graphene. The differences in the basal plane and the undercoordinated edges of graphene and the zigzag versus arm-chair configurations

  8. Photofragment imaging study of the CH2CCH2OH radical intermediate of the OH+allene reaction

    International Nuclear Information System (INIS)

    Raman, Arjun S.; Justine Bell, M.; Lau, K.-C.; Butler, Laurie J.

    2007-01-01

    These velocity map imaging experiments characterize the photolytic generation of one of the two radical intermediates formed when OH reacts via an addition mechanism with allene. The CH 2 CCH 2 OH radical intermediate is generated photolytically from the photodissociation of 2-chloro-2-propen-1-ol at 193 nm. Detecting the Cl atoms using [2+1] resonance-enhanced multiphoton ionization evidences an isotropic angular distribution for the Cl+CH 2 CCH 2 OH photofragments, a spin-orbit branching ratio for Cl( 2 P 1/2 ):Cl( 2 P 3/2 ) of 0.28, and a bimodal recoil kinetic energy distribution. Conservation of momentum and energy allows us to determine from this data the internal energy distribution of the nascent CH 2 CCH 2 OH radical cofragment. To assess the possible subsequent decomposition pathways of this highly vibrationally excited radical intermediate, we include electronic structure calculations at the G3//B3LYP level of theory. They predict the isomerization and dissociation transition states en route from the initial CH 2 CCH 2 OH radical intermediate to the three most important product channels for the OH+allene reaction expected from this radical intermediate: formaldehyde+C 2 H 3 , H+acrolein, and ethene+CHO. We also calculate the intermediates and transition states en route from the other radical adduct, formed by addition of the OH to the center carbon of allene, to the ketene+CH 3 product channel. We compare our results to a previous theoretical study of the O+allyl reaction conducted at the CBS-QB3 level of theory, as the two reactions include several common intermediates

  9. Photofragment imaging study of the CH2CCH2OH radical intermediate of the OH +allene reaction

    Science.gov (United States)

    Raman, Arjun S.; Justine Bell, M.; Lau, Kai-Chung; Butler, Laurie J.

    2007-10-01

    These velocity map imaging experiments characterize the photolytic generation of one of the two radical intermediates formed when OH reacts via an addition mechanism with allene. The CH2CCH2OH radical intermediate is generated photolytically from the photodissociation of 2-chloro-2-propen-1-ol at 193nm. Detecting the Cl atoms using [2+1] resonance-enhanced multiphoton ionization evidences an isotropic angular distribution for the Cl +CH2CCH2OH photofragments, a spin-orbit branching ratio for Cl(P1/22):Cl(P3/22) of 0.28, and a bimodal recoil kinetic energy distribution. Conservation of momentum and energy allows us to determine from this data the internal energy distribution of the nascent CH2CCH2OH radical cofragment. To assess the possible subsequent decomposition pathways of this highly vibrationally excited radical intermediate, we include electronic structure calculations at the G3//B3LYP level of theory. They predict the isomerization and dissociation transition states en route from the initial CH2CCH2OH radical intermediate to the three most important product channels for the OH +allene reaction expected from this radical intermediate: formaldehyde+C2H3, H +acrolein, and ethene+CHO. We also calculate the intermediates and transition states en route from the other radical adduct, formed by addition of the OH to the center carbon of allene, to the ketene+CH3 product channel. We compare our results to a previous theoretical study of the O +allyl reaction conducted at the CBS-QB3 level of theory, as the two reactions include several common intermediates.

  10. Estimation of direct effects for survival data by using the Aalen additive hazards model

    DEFF Research Database (Denmark)

    Martinussen, Torben; Vansteelandt, Stijn; Gerster, Mette

    2011-01-01

    We extend the definition of the controlled direct effect of a point exposure on a survival outcome, other than through some given, time-fixed intermediate variable, to the additive hazard scale. We propose two-stage estimators for this effect when the exposure is dichotomous and randomly assigned...... Aalen's additive regression for the event time, given exposure, intermediate variable and confounders. The second stage involves applying Aalen's additive model, given the exposure alone, to a modified stochastic process (i.e. a modification of the observed counting process based on the first...

  11. Intermediate structure and threshold phenomena

    International Nuclear Information System (INIS)

    Hategan, Cornel

    2004-01-01

    The Intermediate Structure, evidenced through microstructures of the neutron strength function, is reflected in open reaction channels as fluctuations in excitation function of nuclear threshold effects. The intermediate state supporting both neutron strength function and nuclear threshold effect is a micro-giant neutron threshold state. (author)

  12. Improving interMediAte Risk management. MARK study

    Directory of Open Access Journals (Sweden)

    Garcia-Gil Maria

    2011-10-01

    Full Text Available Abstract Background Cardiovascular risk functions fail to identify more than 50% of patients who develop cardiovascular disease. This is especially evident in the intermediate-risk patients in which clinical management becomes difficult. Our purpose is to analyze if ankle-brachial index (ABI, measures of arterial stiffness, postprandial glucose, glycosylated hemoglobin, self-measured blood pressure and presence of comorbidity are independently associated to incidence of vascular events and whether they can improve the predictive capacity of current risk equations in the intermediate-risk population. Methods/Design This project involves 3 groups belonging to REDIAPP (RETICS RD06/0018 from 3 Spanish regions. We will recruit a multicenter cohort of 2688 patients at intermediate risk (coronary risk between 5 and 15% or vascular death risk between 3-5% over 10 years and no history of atherosclerotic disease, selected at random. We will record socio-demographic data, information on diet, physical activity, comorbidity and intermittent claudication. We will measure ABI, pulse wave velocity and cardio ankle vascular index at rest and after a light intensity exercise. Blood pressure and anthropometric data will be also recorded. We will also quantify lipids, glucose and glycosylated hemoglobin in a fasting blood sample and postprandial capillary glucose. Eighteen months after the recruitment, patients will be followed up to determine the incidence of vascular events (later follow-ups are planned at 5 and 10 years. We will analyze whether the new proposed risk factors contribute to improve the risk functions based on classic risk factors. Discussion Primary prevention of cardiovascular diseases is a priority in public health policy of developed and developing countries. The fundamental strategy consists in identifying people in a high risk situation in which preventive measures are effective and efficient. Improvement of these predictions in our country

  13. A method of producing small grain Ru intermediate layers for perpendicular magnetic media

    International Nuclear Information System (INIS)

    Yuan Hua; Qin Yueling; Laughlin, David E.

    2008-01-01

    NiAl + SiO 2 thin films were used as a grain size reducing seedlayer for cobalt alloy granular perpendicular magnetic recording media. The effect of this NiAl + SiO 2 seedlayer on the microstructure and crystalline orientation of Ru intermediate layer has been investigated. By co-sputtering the composite NiAl + SiO 2 seedlayer, the smallest average grain diameter of NiAl was significantly reduced to about 2.5 nm. The grain size of the subsequent Ru intermediate layer was reduced to about 4 nm. X-ray diffraction results indicate an epitaxial orientation relationship of NiAl (110) // Ru (0002) between the two layers. Moreover, significant improvement of this epitaxial relationship was developed, which produced narrow c-axis distribution of the Ru intermediate layer with small grain size. The addition of the NiAl + SiO 2 seedlayer is a very promising approach to reduce the Ru intermediate layer grain size and eventually the magnetic layer grain size for perpendicular magnetic recording media without deterioration of other properties of thin films

  14. When should green technology support policies supplement the carbon price? The case of the electricity sector

    International Nuclear Information System (INIS)

    Lecuyer, Oskar

    2013-01-01

    This thesis contributes to the literature on optimal policy choice. It studies the use of policy combinations to mitigate greenhouse gases emissions from electricity production. One finding applies to cases where uncertainty is such that the risk of a nil carbon price cannot be excluded. A cap on emissions alone may then not trigger enough abatements, justifying the addition of e.g. a renewable subsidy. When considering a transition toward a carbon free electricity sector, capital accumulation causes complex dynamic effects to happen. We find that decisions taken by comparing the leveled costs of abatement technologies, even including carbon costs, would favor intermediate technologies (e.g. gas plants) to the detriment of more-expensive but lower-carbon technologies (renewable power), leading to a suboptimal investment schedule. This thesis also studies the effects of marginal policy changes in a mix comprising the main French instruments. We find that surprisingly, adding a tariff for renewables financed by a tax on electricity consumption to a cap on emissions and a subsidy for energy efficiency will reduce the consumer electricity price when the non-renewable production is fixed and does not depend on the carbon price. The assessment of the French climate policies in the electricity sector shows that overlapping policies for mitigation may be justified by multiple carbon price failures, even if the ideal long-term policy mix depends on the carbon price trajectory. (author)

  15. Intermediate algebra & analytic geometry

    CERN Document Server

    Gondin, William R

    1967-01-01

    Intermediate Algebra & Analytic Geometry Made Simple focuses on the principles, processes, calculations, and methodologies involved in intermediate algebra and analytic geometry. The publication first offers information on linear equations in two unknowns and variables, functions, and graphs. Discussions focus on graphic interpretations, explicit and implicit functions, first quadrant graphs, variables and functions, determinate and indeterminate systems, independent and dependent equations, and defective and redundant systems. The text then examines quadratic equations in one variable, system

  16. The cocaine and heroin markets in the era of globalisation and drug reduction policies.

    Science.gov (United States)

    Costa Storti, Cláudia; De Grauwe, Paul

    2009-11-01

    Despite the large volume of public effort devoted to restrain drug supply and the growing attention given to drug demand reduction policies, the use of cocaine and heroin remains steady. Furthermore, retail drug prices have fallen significantly in Europe and the US. This puzzling evidence leads us to develop a model aiming at systematically analysing illicit drug markets. We model the markets of cocaine and heroin from production to the final retail markets. One novelty of the analysis consists in characterising the retail market as a monopolistic competitive one. Then, upper level dealers have some market power in the retail market. This allows them to charge a markup and to earn extra profits. These extra profits attract newcomers so that profits tend to fall over time. Theoretical model was used to analyse the effect of supply containment policies on the retail market, the producer market and the export-import business. This introduces the discussion of the impact of demand reduction policies on the high level traffickers' profit. Finally, globalisation enters in the model. Law enforcement measures increase the risk premia received by the lower and higher level traffickers. Consequently, trafficking intermediation margins tend to increase. However, globalisation has the opposite effect. It lowers intermediation margins and, then, pushes retail prices down, thereby stimulating consumption. In doing so, globalisation offsets the effects of supply containment policies. Finally, we discuss how the effectiveness of supply containment policies can be enhanced by combining them with demand reduction policies.

  17. Regularities of intermediate adsorption complex relaxation

    International Nuclear Information System (INIS)

    Manukova, L.A.

    1982-01-01

    The experimental data, characterizing the regularities of intermediate adsorption complex relaxation in the polycrystalline Mo-N 2 system at 77 K are given. The method of molecular beam has been used in the investigation. The analytical expressions of change regularity in the relaxation process of full and specific rates - of transition from intermediate state into ''non-reversible'', of desorption into the gas phase and accumUlation of the particles in the intermediate state are obtained

  18. FINANCIAL INTERMEDIATION, ENTREPRENEURSHIP AND ECONOMIC GROWTH

    OpenAIRE

    Wenli Cheng

    2007-01-01

    This paper presents a simple general equilibrium model of financial intermediation, entrepreneurship and economic growth. In this model, the role of financial intermediation is to pool savings and to lend the pooled funds to an entrepreneur, who in turn invests the funds in a new production technology. The adoption of the new production technology improves individual real income. Thus financial intermediation promotes economic growth through affecting individuals’ saving behaviour and enabl...

  19. Some Intermediate-Level Violin Concertos.

    Science.gov (United States)

    Abramson, Michael

    1997-01-01

    Contends that many violin students attempt difficult concertos before they are technically or musically prepared. Identifies a variety of concertos at the intermediate and advanced intermediate-level for students to study and master before attempting the advanced works by Bach and Mozart. Includes concertos by Vivaldi, Leclair, Viotti, Haydn,…

  20. Green electricity policies in the Netherlands: an analysis of policy decisions

    International Nuclear Information System (INIS)

    Rooijen, Sascha N.M. van; Wees, Mark T. van

    2006-01-01

    Over the last decades, fundamental changes can be observed in both market conditions and the national policy framework for green electricity in the Netherlands. The Dutch Government has regularly intervened in markets, demonstrating fundamental shifts in policy and approach. This study aims to analyse the developments in renewable energy policy making in the Netherlands. It assesses changes in the choice of policy instruments and target groups, the role of stakeholders, and offers explanations behind policy successes and failures. Dutch green electricity policy over the last decade can be characterised roughly by three phases: in the early 1990s, the government negotiated voluntary agreements with the energy distribution sector on targets for green electricity sales, which were never met. In the second half of the 1990s, a regulatory energy tax was introduced, from which customers of green electricity were exempt. This led to a substantial increase in demand, which was largely met by green electricity imports, and did not lead to additional domestic renewable energy capacity. Finally, a change in policy has taken place recently (2003) shifting the focus from promotion of demand to the promotion of supply through a system of regulated feed-in tariffs. Despite the renewable energy policies, growth of the renewable energy market in the Netherlands has been small and targets have not been fully met. The Dutch government has not yet succeeded in substantially reducing market uncertainties and in building confidence among market parties, because the policies have not been stable and policy objectives have frequently been partly ambiguous. In addition, the influence of stakeholders in renewable energy policy making has been small which has the early acceptance and implementation of alternative policies

  1. Welding. Performance Objectives. Intermediate Course.

    Science.gov (United States)

    Vincent, Kenneth

    Several intermediate performance objectives and corresponding criterion measures are listed for each of nine terminal objectives for an intermediate welding course. The materials were developed for a 36-week (3 hours daily) course designed to prepare the student for employment in the field of welding. Electric welding and specialized (TIG & MIG)…

  2. 7 CFR 1735.18 - Additional equity.

    Science.gov (United States)

    2010-01-01

    ... AGRICULTURE GENERAL POLICIES, TYPES OF LOANS, LOAN REQUIREMENTS-TELECOMMUNICATIONS PROGRAM Loan Purposes and Basic Policies § 1735.18 Additional equity. If determined by the Administrator to be necessary for loan security, a borrower applying for an initial loan shall increase its net worth as a percentage of assets to...

  3. Money distribution with intermediation

    OpenAIRE

    Teles, Caio Augusto Colnago

    2013-01-01

    This pap er analyzes the distribution of money holdings in a commo dity money search-based mo del with intermediation. Intro ducing heterogeneity of costs to the Kiyotaki e Wright ( 1989 ) mo del, Cavalcanti e Puzzello ( 2010) gives rise to a non-degenerated distribution of money. We extend further this mo del intro ducing intermediation in the trading pro cess. We show that the distribution of money matters for savings decisions. This gives rises to a xed p oint problem for the ...

  4. Search for intermediate vector bosons

    International Nuclear Information System (INIS)

    Klajn, D.B.; Rubbia, K.; Meer, S.

    1983-01-01

    Problem of registration and search for intermediate vector bosons is discussed. According to weak-current theory there are three intermediate vector bosons with +1(W + )-1(W - ) and zero (Z 0 ) electric charges. It was suggested to conduct the investigation into particles in 1976 by cline, Rubbia and Makintair using proton-antiproton beams. Major difficulties of the experiment are related to the necessity of formation of sufficient amount of antiparticles and the method of antiproton beam ''cooling'' for the purpose of reduction of its random movements. The stochastic method was suggested by van der Meer in 1968 as one of possible cooling methods. Several large detectors were designed for searching intermediate vector bosons

  5. Validation of intermediate end points in cancer research.

    Science.gov (United States)

    Schatzkin, A; Freedman, L S; Schiffman, M H; Dawsey, S M

    1990-11-21

    Investigations using intermediate end points as cancer surrogates are quicker, smaller, and less expensive than studies that use malignancy as the end point. We present a strategy for determining whether a given biomarker is a valid intermediate end point between an exposure and incidence of cancer. Candidate intermediate end points may be selected from case series, ecologic studies, and animal experiments. Prospective cohort and sometimes case-control studies may be used to quantify the intermediate end point-cancer association. The most appropriate measure of this association is the attributable proportion. The intermediate end point is a valid cancer surrogate if the attributable proportion is close to 1.0, but not if it is close to 0. Usually, the attributable proportion is close to neither 1.0 nor 0; in this case, valid surrogacy requires that the intermediate end point mediate an established exposure-cancer relation. This would in turn imply that the exposure effect would vanish if adjusted for the intermediate end point. We discuss the relative advantages of intervention and observational studies for the validation of intermediate end points. This validation strategy also may be applied to intermediate end points for adverse reproductive outcomes and chronic diseases other than cancer.

  6. Biocatalytic Synthesis of Chiral Pharmaceutical Intermediates

    Directory of Open Access Journals (Sweden)

    Ramesh N. Patel

    2004-01-01

    Full Text Available The production of single enantiomers of drug intermediates has become increasingly important in the pharmaceutical industry. Chiral intermediates and fine chemicals are in high demand from both the pharmaceutical and agrochemical industries for the preparation of bulk drug substances and agricultural products. The enormous potential of microorganisms and enzymes for the transformation of synthetic chemicals with high chemo-, regio- and enantioselectivities has been demonstrated. In this article, biocatalytic processes are described for the synthesis of chiral pharmaceutical intermediates.

  7. Simplifying biochemical models with intermediate species

    DEFF Research Database (Denmark)

    Feliu, Elisenda; Wiuf, Carsten

    2013-01-01

    techniques, we study systematically the effects of intermediate, or transient, species in biochemical systems and provide a simple, yet rigorous mathematical classification of all models obtained from a core model by including intermediates. Main examples include enzymatic and post-translational modification...... systems, where intermediates often are considered insignificant and neglected in a model, or they are not included because we are unaware of their existence. All possible models obtained from the core model are classified into a finite number of classes. Each class is defined by a mathematically simple...... canonical model that characterizes crucial dynamical properties, such as mono- and multistationarity and stability of steady states, of all models in the class. We show that if the core model does not have conservation laws, then the introduction of intermediates does not change the steady...

  8. Why do policies change? Institutions, interests, ideas and networks in three cases of policy reform.

    Science.gov (United States)

    Shearer, Jessica C; Abelson, Julia; Kouyaté, Bocar; Lavis, John N; Walt, Gill

    2016-11-01

    Policy researchers have used various categories of variables to explain why policies change, including those related to institutions, interests and ideas. Recent research has paid growing attention to the role of policy networks-the actors involved in policy-making, their relationships with each other, and the structure formed by those relationships-in policy reform across settings and issues; however, this literature has largely ignored the theoretical integration of networks with other policy theories, including the '3Is' of institutions, interests and ideas. This article proposes a conceptual framework integrating these variables and tests it on three cases of policy change in Burkina Faso, addressing the need for theoretical integration with networks as well as the broader aim of theory-driven health policy analysis research in low- and middle-income countries. We use historical process tracing, a type of comparative case study, to interpret and compare documents and in-depth interview data within and between cases. We found that while network changes were indeed associated with policy reform, this relationship was mediated by one or more of institutions, interests and ideas. In a context of high donor dependency, new donor rules affected the composition and structure of actors in the networks, which enabled the entry and dissemination of new ideas and shifts in the overall balance of interest power ultimately leading to policy change. The case of strategic networking occurred in only one case, by civil society actors, suggesting that network change is rarely the spark that initiates the process towards policy change. This analysis highlights the important role of changes in institutions and ideas to drive policymaking, but hints that network change is a necessary intermediate step in these processes. © The Author 2016. Published by Oxford University Press in association with The London School of Hygiene and Tropical Medicine. All rights reserved. For

  9. Reactions of stabilized Criegee Intermediates

    Science.gov (United States)

    Vereecken, Luc; Harder, Hartwig; Novelli, Anna

    2014-05-01

    Carbonyl oxides (Criegee intermediates) were proposed as key intermediates in the gas phase ozonolysis of alkenes in 1975 by Rudolf Criegee. Despite the importance of ozonolysis in atmospheric chemistry, direct observation of these intermediates remained elusive, with only indirect experimental evidence for their role in the oxidation of hydrocarbons, e.g. through scavenging experiments. Direct experimental observation of stabilized CI has only been achieved since 2008. Since then, a concerted effort using experimental and theoretical means is in motion to characterize the chemistry and kinetics of these reactive intermediates. We present the results of theoretical investigations of the chemistry of Criegee intermediates with a series of coreactants which may be of importance in the atmosphere, in experimental setups, or both. This includes the CI+CI cross-reaction, which proceeds with a rate coefficient near the collision limit and can be important in experimental conditions. The CI + alkene reactions show strong dependence of the rate coefficient depending on the coreactants, but is generally found to be rather slow. The CI + ozone reaction is sufficiently fast to occur both in experiment and the free troposphere, and acts as a sink for CI. The reaction of CI with hydroperoxides, ROOH, is complex, and leads both to the formation of oligomers, as to the formation of reactive etheroxides, with a moderately fast rate coefficient. The importance of these reactions is placed in the context of the reaction conditions in different atmospheric environments ranging from unpolluted to highly polluted.

  10. The intermediate endpoint effect in logistic and probit regression

    Science.gov (United States)

    MacKinnon, DP; Lockwood, CM; Brown, CH; Wang, W; Hoffman, JM

    2010-01-01

    Background An intermediate endpoint is hypothesized to be in the middle of the causal sequence relating an independent variable to a dependent variable. The intermediate variable is also called a surrogate or mediating variable and the corresponding effect is called the mediated, surrogate endpoint, or intermediate endpoint effect. Clinical studies are often designed to change an intermediate or surrogate endpoint and through this intermediate change influence the ultimate endpoint. In many intermediate endpoint clinical studies the dependent variable is binary, and logistic or probit regression is used. Purpose The purpose of this study is to describe a limitation of a widely used approach to assessing intermediate endpoint effects and to propose an alternative method, based on products of coefficients, that yields more accurate results. Methods The intermediate endpoint model for a binary outcome is described for a true binary outcome and for a dichotomization of a latent continuous outcome. Plots of true values and a simulation study are used to evaluate the different methods. Results Distorted estimates of the intermediate endpoint effect and incorrect conclusions can result from the application of widely used methods to assess the intermediate endpoint effect. The same problem occurs for the proportion of an effect explained by an intermediate endpoint, which has been suggested as a useful measure for identifying intermediate endpoints. A solution to this problem is given based on the relationship between latent variable modeling and logistic or probit regression. Limitations More complicated intermediate variable models are not addressed in the study, although the methods described in the article can be extended to these more complicated models. Conclusions Researchers are encouraged to use an intermediate endpoint method based on the product of regression coefficients. A common method based on difference in coefficient methods can lead to distorted

  11. Transport policies related to climate change mitigation: the case of Denmark

    Energy Technology Data Exchange (ETDEWEB)

    Vad Mathiesen, B.; Kappel, J.

    2013-03-15

    This report presents the Danish national policies on reducing the emissions of greenhouse gasses and reducing Denmark's dependency on fossil fuels in the transport sector, as well as some of the results of the policies. Systematic focus on efficient transport and climate mitigation started in 2008 and 2009 with a change - not only in the wording and in the political visions - but also in the actual prioritisation of investments and policies to a very large extent. In March 2012 another milestone was set by the Government, to have Denmark based on 100% renewable energy in 2050. This entails large challenges for the transport sectors, which has not yet been systematically analysed from any Governmental body. In this report we list projects which have done so. The first chapter describes policies and initiatives of international relevance within climate mitigation. The following chapters explain in further debt these policies and their effects as well as a number of additional policies and initiatives related to climate mitigation and transport. The private sector and local government has proven important in connection with an efficient transport sector. Hence selected local and regional projects and their results are introduced as well. To provide an overview of current trends, related scientific projects and other analyses on climate change mitigation and transport are given in the report. The references used in this report can also serve as a source of data and inspiration for the reader. This report is prepared as one of many inputs to the analyses conducted in The Swedish Government's Commission on fossil-free road transport. The task of this Commission is to: ''review alternative developments of fuels and vehicles for fossil-free road transport, to consider measures and policy options that would enable the Swedish road transport system to become climate neutral by 2050, and to propose intermediate emission reduction targets for years such as

  12. Energy policy and regional inequalities in the Brazilian economy

    International Nuclear Information System (INIS)

    Santos, Gervasio F.; Haddad, Eduardo A.; Hewings, Geoffrey J.D.

    2013-01-01

    The objective of this paper is to evaluate the long-run regional impacts of the tariff policy of the Brazilian electric power sector. This sector has undergone a reform process that started in the 1990s. Since the beginning of the reform, two spatial trends of distribution of electric power tariffs have emerged among the Brazilian states, one of convergence and another of spatial divergence. These trends have been guided by the new electric power tariff policy and by the spatial features of the Brazilian economy, which is marked by a high degree of spatial concentration and hierarchical distribution of large markets. In addition, because of the presence of strong economies of scale, the recent electric power prices differentials might be caused by differentials in market size that provide better conditions for the achievement of economies of scale for electric power utility companies located in larger markets. Given the role of electric power as an important intermediate input in the production process and the interdependence between sectors, an Energy Interregional Computable General Equilibrium model was used to simulate the long-run regional impacts of electric power tariff policy in Brazil. The simulations showed that the heterogeneity of energy-intensity and the differentials of energy substitution drive the spatial impacts of changes in electric power prices. On the other hand, the recent trend of spatial dispersion of electric power prices might contribute to a decrease in the long-run economic growth and to an increase in the regional inequalities in Brazil. - Highlights: ► We model the regional impacts of tariff policy of the electric power sector in Brazil. ► High electric power tariffs increases in regions with higher electric-power-intensity. ► Heterogeneity of energy supply determines an unequal pattern of energy substitution. ► Low possibilities of energy substitution generate the most negative economic impacts

  13. Action taken by ENRESA and the NPPs with a view to reducing the production of low and intermediate level wastes

    International Nuclear Information System (INIS)

    Morales, A.; Rojo, F.

    1996-01-01

    In those countries in which the responsibilities of the different organizations involved in the management of low and intermediate level radioactive wastes (Regulatory Body, Agency, Facility Operators and Producers) are perfectly defined and a definitive Waste Disposal Facility is in operation, the next phase in order of importance consists of addressing a waste volume reduction policy aimed at optimizing storage capacity

  14. Gravity with Intermediate Goods Trade

    Directory of Open Access Journals (Sweden)

    Sujin Jang

    2017-12-01

    Full Text Available This paper derives the gravity equation with intermediate goods trade. We extend a standard monopolistic competition model to incorporate intermediate goods trade, and show that the gravity equation with intermediates trade is identical to the one without it except in that gross output should be used as the output measure instead of value added. We also show that the output elasticity of trade is significantly underestimated when value added is used as the output measure. This implies that with the conventional gravity equation, the contribution of output growth can be substantially underestimated and the role of trade costs reduction can be exaggerated in explaining trade expansion, as we demonstrate for the case of Korea's trade growth between 1995 and 2007.

  15. Feasibility of large volume casting cementation process for intermediate level radioactive waste

    International Nuclear Information System (INIS)

    Chen Zhuying; Chen Baisong; Zeng Jishu; Yu Chengze

    1988-01-01

    The recent tendency of radioactive waste treatment and disposal both in China and abroad is reviewed. The feasibility of the large volume casting cementation process for treating and disposing the intermediate level radioactive waste from spent fuel reprocessing plant in shallow land is assessed on the basis of the analyses of the experimental results (such as formulation study, solidified radioactive waste properties measurement ect.). It can be concluded large volume casting cementation process is a promising, safe and economic process. It is feasible to dispose the intermediate level radioactive waste from reprocessing plant it the disposal site chosen has resonable geological and geographical conditions and some additional effective protection means are taken

  16. Mobile communication and intermediality

    DEFF Research Database (Denmark)

    Helles, Rasmus

    2013-01-01

    communicative affordances of mobile devices in order to understand how people choose between them for different purposes. It is argued that mobile communication makes intermediality especially central, as the choice of medium is detached from the location of stationary media and begins to follow the user across......The article argues the importance of intermediality as a concept for research in mobile communication and media. The constant availability of several, partially overlapping channels for communication (texting, calls, email, Facebook, etc.) requires that we adopt an integrated view of the various...

  17. Classical model of intermediate statistics

    International Nuclear Information System (INIS)

    Kaniadakis, G.

    1994-01-01

    In this work we present a classical kinetic model of intermediate statistics. In the case of Brownian particles we show that the Fermi-Dirac (FD) and Bose-Einstein (BE) distributions can be obtained, just as the Maxwell-Boltzmann (MD) distribution, as steady states of a classical kinetic equation that intrinsically takes into account an exclusion-inclusion principle. In our model the intermediate statistics are obtained as steady states of a system of coupled nonlinear kinetic equations, where the coupling constants are the transmutational potentials η κκ' . We show that, besides the FD-BE intermediate statistics extensively studied from the quantum point of view, we can also study the MB-FD and MB-BE ones. Moreover, our model allows us to treat the three-state mixing FD-MB-BE intermediate statistics. For boson and fermion mixing in a D-dimensional space, we obtain a family of FD-BE intermediate statistics by varying the transmutational potential η BF . This family contains, as a particular case when η BF =0, the quantum statistics recently proposed by L. Wu, Z. Wu, and J. Sun [Phys. Lett. A 170, 280 (1992)]. When we consider the two-dimensional FD-BE statistics, we derive an analytic expression of the fraction of fermions. When the temperature T→∞, the system is composed by an equal number of bosons and fermions, regardless of the value of η BF . On the contrary, when T=0, η BF becomes important and, according to its value, the system can be completely bosonic or fermionic, or composed both by bosons and fermions

  18. Using Peephole Optimization on Intermediate Code

    NARCIS (Netherlands)

    Tanenbaum, A.S.; van Staveren, H.; Stevenson, J.W.

    1982-01-01

    Many portable compilers generate an intermediate code that is subsequently translated into the target machine's assembly language. In this paper a stack-machine-based intermediate code suitable for algebraic languages (e.g., PASCAL, C, FORTRAN) and most byte-addressed mini- and microcomputers is

  19. Pair production of intermediate vector bosons

    International Nuclear Information System (INIS)

    Mikaelian, K.O.

    1979-01-01

    The production of intermediate vector boson pairs W + W - , Z 0 Z 0 , W +- Z 0 and W +- γ in pp and p anti p collisions is discussed. The motivation is to detect the self-interactions among the four intermediate vector bosons

  20. Isoporphyrin intermediate in heme oxygenase catalysis. Oxidation of alpha-meso-phenylheme.

    Science.gov (United States)

    Evans, John P; Niemevz, Fernando; Buldain, Graciela; de Montellano, Paul Ortiz

    2008-07-11

    Human heme oxygenase-1 (hHO-1) catalyzes the O2- and NADPH-dependent oxidation of heme to biliverdin, CO, and free iron. The first step involves regiospecific insertion of an oxygen atom at the alpha-meso carbon by a ferric hydroperoxide and is predicted to proceed via an isoporphyrin pi-cation intermediate. Here we report spectroscopic detection of a transient intermediate during oxidation by hHO-1 of alpha-meso-phenylheme-IX, alpha-meso-(p-methylphenyl)-mesoheme-III, and alpha-meso-(p-trifluoromethylphenyl)-mesoheme-III. In agreement with previous experiments (Wang, J., Niemevz, F., Lad, L., Huang, L., Alvarez, D. E., Buldain, G., Poulos, T. L., and Ortiz de Montellano, P. R. (2004) J. Biol. Chem. 279, 42593-42604), only the alpha-biliverdin isomer is produced with concomitant formation of the corresponding benzoic acid. The transient intermediate observed in the NADPH-P450 reductase-catalyzed reaction accumulated when the reaction was supported by H2O2 and exhibited the absorption maxima at 435 and 930 nm characteristic of an isoporphyrin. Product analysis by reversed phase high performance liquid chromatography and liquid chromatography electrospray ionization mass spectrometry of the product generated with H2O2 identified it as an isoporphyrin that, on quenching, decayed to benzoylbiliverdin. In the presence of H218O2, one labeled oxygen atom was incorporated into these products. The hHO-1-isoporphyrin complexes were found to have half-lives of 1.7 and 2.4 h for the p-trifluoromethyl- and p-methyl-substituted phenylhemes, respectively. The addition of NADPH-P450 reductase to the H2O2-generated hHO-1-isoporphyrin complex produced alpha-biliverdin, confirming its role as a reaction intermediate. Identification of an isoporphyrin intermediate in the catalytic sequence of hHO-1, the first such intermediate observed in hemoprotein catalysis, completes our understanding of the critical first step of heme oxidation.

  1. Results of intermediate-scale hot isostatic press can experiments

    International Nuclear Information System (INIS)

    Nelson, L.O.; Vinjamuri, K.

    1995-05-01

    Radioactive high-level waste (HLW) has been managed at the Idaho Chemical Processing Plant (ICPP) for a number of years. Since 1963, liquid HLW has been solidified into a granular solid (calcine). Presently, over 3,800 m 3 of calcine is stored in partially-underground stainless steel bins. Four intermediate- scale HLW can tests (two 6-in OD x 12-in tall and two 4-in OD x 7-in tall) are described and compared to small-scale HIP can tests (1- to 3-in OD x 1- to 4.5-in tall). The intermediate-scale HIP cans were loaded with a 70/30 calcine/frit blend and HIPped at an off-site facility at 1050 degrees C; and 20 ksi. The dimensions of two cans (4-in OD x 7-in tall) were monitored during the HIP cycle with eddy-current sensors. The sensor measurements indicated that can deformation occurs rapidly at 700 degrees C; after which, there is little additional can shrinkage. HIP cans were subjected to a number of analyses including calculation of the overall packing efficiency (56 to 59%), measurement of glass-ceramic (3.0 to 3.2 g/cc), 14-day MCC-1 leach testing (total mass loss rates 2 day), and scanning electron microscopy (SEM). Based on these analyses, the glass-ceramic material produced in intermediate-scale cans is similar to material produced in small-scale cans. No major scale-up problems were indicated. Based on the packing efficiency observed in intermediate- and small-scale tests, the overall packing efficiency of production-scale (24-in OD x 36- to 190-in tall) cans would be approximately 64% for a pre-HIP right-circular cylinder geometry. An efficiency of 64% would represent a volume reduction factor of 2.5 over a candidate glass waste prepared at 33 wt% waste loading

  2. Novel semiconductor solar cell structures: The quantum dot intermediate band solar cell

    International Nuclear Information System (INIS)

    Marti, A.; Lopez, N.; Antolin, E.; Canovas, E.; Stanley, C.; Farmer, C.; Cuadra, L.; Luque, A.

    2006-01-01

    The Quantum Dot Intermediate Band Solar Cell (QD-IBSC) has been proposed for studying experimentally the operating principles of a generic class of photovoltaic devices, the intermediate band solar cells (IBSC). The performance of an IBSC is based on the properties of a semiconductor-like material which is characterised by the existence of an intermediate band (IB) located within what would otherwise be its conventional bandgap. The improvement in efficiency of the cell arises from its potential (i) to absorb below bandgap energy photons and thus produce additional photocurrent, and (ii) to inject this enhanced photocurrent without degrading its output photo-voltage. The implementation of the IBSC using quantum dots (QDs) takes advantage of the discrete nature of the carrier density of states in a 0-dimensional nano-structure, an essential property for realising the IB concept. In the QD-IBSC, the IB arises from the confined electron states in an array of quantum dots. This paper reviews the operation of the first prototype QD-IBSCs and discusses some of the lessons learnt from their characterisation

  3. Novel semiconductor solar cell structures: The quantum dot intermediate band solar cell

    Energy Technology Data Exchange (ETDEWEB)

    Marti, A. [Instituto de Energia Solar-UPM, ETSIT de Madrid, Ciudad Universitaria sn, 28040 Madrid (Spain)]. E-mail: amarti@etsit.upm.es; Lopez, N. [Instituto de Energia Solar-UPM, ETSIT de Madrid, Ciudad Universitaria sn, 28040 Madrid (Spain); Antolin, E. [Instituto de Energia Solar-UPM, ETSIT de Madrid, Ciudad Universitaria sn, 28040 Madrid (Spain); Canovas, E. [Instituto de Energia Solar-UPM, ETSIT de Madrid, Ciudad Universitaria sn, 28040 Madrid (Spain); Stanley, C. [Department of Electronics and Electrical Engineering, University of Glasgow, Glasgow G12 8QQ (United Kingdom); Farmer, C. [Department of Electronics and Electrical Engineering, University of Glasgow, Glasgow G12 8QQ (United Kingdom); Cuadra, L. [Departamento de Teoria de la Senal y Comunicaciones- Escuela Politecnica Superior, Universidad de Alcala, Ctra. Madrid-Barcelona, km. 33600, 28805-Alcala de Henares (Madrid) (Spain); Luque, A. [Instituto de Energia Solar-UPM, ETSIT de Madrid, Ciudad Universitaria sn, 28040 Madrid (Spain)

    2006-07-26

    The Quantum Dot Intermediate Band Solar Cell (QD-IBSC) has been proposed for studying experimentally the operating principles of a generic class of photovoltaic devices, the intermediate band solar cells (IBSC). The performance of an IBSC is based on the properties of a semiconductor-like material which is characterised by the existence of an intermediate band (IB) located within what would otherwise be its conventional bandgap. The improvement in efficiency of the cell arises from its potential (i) to absorb below bandgap energy photons and thus produce additional photocurrent, and (ii) to inject this enhanced photocurrent without degrading its output photo-voltage. The implementation of the IBSC using quantum dots (QDs) takes advantage of the discrete nature of the carrier density of states in a 0-dimensional nano-structure, an essential property for realising the IB concept. In the QD-IBSC, the IB arises from the confined electron states in an array of quantum dots. This paper reviews the operation of the first prototype QD-IBSCs and discusses some of the lessons learnt from their characterisation.

  4. Interpretation and code generation based on intermediate languages

    DEFF Research Database (Denmark)

    Kornerup, Peter; Kristensen, Bent Bruun; Madsen, Ole Lehrmann

    1980-01-01

    The possibility of supporting high level languages through intermediate languages to be used for direct interpretation and as intermediate forms in compilers is investigated. An accomplished project in the construction of an interpreter and a code generator using one common intermediate form...

  5. Onset of chaos in Josephson junctions with intermediate damping

    International Nuclear Information System (INIS)

    Yao, X.; Wu, J.Z.; Ting, C.S.

    1990-01-01

    By use of the analytical solution of the Stewart-McCumber equation including quadratic damping and dc bias, the Melnikov method has been extended to the parameter regions of intermediate damping and dc bias for the Josephson junctions with quadratic damping and with linear damping and cosφ term. The comparison between the thresholds predicted by the Melnikov method and that derived from numerical simulation has been studied. In addition, the validity conditions for the Melnikov threshold are also discussed

  6. United Kingdom government policy towards radioactive waste

    International Nuclear Information System (INIS)

    Pritchard, G.

    1986-01-01

    There are three areas of radioactive waste management which exemplify, beyond any reasonable doubt, that the United Kingdom has in the past (and intends in the future), to pursue a policy of dispersal and disposal of radioactive wastes: These are: (I) dumping of low-level waste in the deep ocean and, on a parallel, seabed emplacement of highly active waste; (II) the liquid discharges from Windscale into the Irish Sea; and (III) land dumping of low- and intermediate-level waste

  7. Search for intermediate vector bosons

    International Nuclear Information System (INIS)

    Cline, D.B.; Rubbia, C.; van der Meer, S.

    1982-01-01

    Over the past 15 years a new class of unified theories has been developed to describe the forces acting between elementary particles. The most successful of the new theories establishes a link between electromagnetism and the weak force. A crucial prediction of this unified electroweak theory is the existence of three massive particles called intermediate vector bosons. If these intermediate vector bosons exist and if they have properties attributed to them by electroweak theory, they should soon be detected, as the world's first particle accelerator with enough energy to create such particles has recently been completed at the European Organization for Nuclear Research (CERN) in Geneva. The accelerator has been converted to a colliding beam machine in which protons and antiprotons collide head on. According to electroweak theory, intermediate vector bosons can be created in proton-antiproton collisions. (SC)

  8. Energy-momentum tensor of intermediate vector bosons in an external electromagnetic field

    International Nuclear Information System (INIS)

    Mostepanenko, V.M.; Sokolov, I.Yu.

    1988-01-01

    Expressions are obtained for the canonical and metric energy-momentum tensors of the vector field of intermediate bosons in an external electromagnetic field. It is shown that in the case of a gyromagnetic ratio not equal to unity the energy-momentum tensor cannot be symmetrized on its indices, and an additional term proportional to the anomalous magnetic moment appears in the conservation laws. A modification of the canonical formalism for scalar and vector fields in an external field is proposed in accordance with which the Hamiltonian density is equal to the 00 component of the energy-momentum tensor. An expression for the energy-momentum tensor of a closed system containing a gauge field of intermediate bosons and an electromagnetic field is obtained

  9. 39 CFR 3001.39 - Intermediate decisions.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Intermediate decisions. 3001.39 Section 3001.39 Postal Service POSTAL REGULATORY COMMISSION PERSONNEL RULES OF PRACTICE AND PROCEDURE Rules of General Applicability § 3001.39 Intermediate decisions. (a) Initial decision by presiding officer. In any proceedings in...

  10. 42 CFR 54.12 - Treatment of intermediate organizations.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Treatment of intermediate organizations. 54.12... intermediate organizations. If a nongovernmental organization (referred to here as an “intermediate organization”), acting under a contract or other agreement with the Federal Government or a State or local...

  11. Inoculation Policies in Response to Terrorist or WMD Attacks: Additional Factors to Consider

    International Nuclear Information System (INIS)

    Leitner, P. M.

    2007-01-01

    When viewed on its own merits, the debate over who should be inoculated during a period of biological emergency is a rather straightforward public policy decision. The classic public policy 'balancing act' decision-making model is defaulted to as issues of fairness, efficiency, cost-effectiveness, adequacy of supply, mission performance, and constituencies are arrayed and adjudicated. This mainstream approach is appropriate as far as it goes but it also exemplifies a series of structural and perceptual weaknesses when applied to wartime or localized terrorism scenarios. In fact, the establishment of a vaccination policy appropriate to a flu pandemic falls squarely within this mainstream debate. Although the notion of a pandemic carries an assumption of a great many fatalities it does not possess the fear quotient, uncertainty, horror, unnaturalness, or inevitability of a bio-terror or biological warfare incident. As a result, the reliability and responsiveness of key personnel responding to a flu pandemic should be less of an issue than it will be in the event of an intentional man-made biological incident. The principal policy weakness in instances an intentional bio-attack stems from a generalized failure, or refusal, to systematically study the behavior of key personnel, first-responders, soldiers, or critical senior leadership during severe crises occurring in their own backyards. In other words, when the 'balloon goes up' how many of your responders and critical personnel will show up for work? This presentation considers many of the 'unaddressed' factors that experience has shown may have a determinative effect upon the efficacy of a response to a biological incident. Lessons are drawn from experiences of US forces station in the former West Germany, US Defense Department Continuity of Operations Programs, Hurricane Katrina, and the 9/11 attacks on the United States. (author)

  12. The role of public policies in reducing smoking prevalence: results from the Michigan SimSmoke tobacco policy simulation model.

    Science.gov (United States)

    Levy, David T; Huang, An-Tsun; Havumaki, Joshua S; Meza, Rafael

    2016-05-01

    Michigan has implemented several of the tobacco control policies recommended by the World Health Organization MPOWER goals. We consider the effect of those policies and additional policies consistent with MPOWER goals on smoking prevalence and smoking-attributable deaths (SADs). The SimSmoke tobacco control policy simulation model is used to examine the effect of past policies and a set of additional policies to meet the MPOWER goals. The model is adapted to Michigan using state population, smoking, and policy data starting in 1993. SADs are estimated using standard attribution methods. Upon validating the model, SimSmoke is used to distinguish the effect of policies implemented since 1993 against a counterfactual with policies kept at their 1993 levels. The model is then used to project the effect of implementing stronger policies beginning in 2014. SimSmoke predicts smoking prevalence accurately between 1993 and 2010. Since 1993, a relative reduction in smoking rates of 22 % by 2013 and of 30 % by 2054 can be attributed to tobacco control policies. Of the 22 % reduction, 44 % is due to taxes, 28 % to smoke-free air laws, 26 % to cessation treatment policies, and 2 % to youth access. Moreover, 234,000 SADs are projected to be averted by 2054. With additional policies consistent with MPOWER goals, the model projects that, by 2054, smoking prevalence can be further reduced by 17 % with 80,000 deaths averted relative to the absence of those policies. Michigan SimSmoke shows that tobacco control policies, including cigarette taxes, smoke-free air laws, and cessation treatment policies, have substantially reduced smoking and SADs. Higher taxes, strong mass media campaigns, and cessation treatment policies would further reduce smoking prevalence and SADs.

  13. Bacterial intermediate filaments

    DEFF Research Database (Denmark)

    Charbon, Godefroid; Cabeen, M.; Jacobs-Wagner, C.

    2009-01-01

    Crescentin, which is the founding member of a rapidly growing family of bacterial cytoskeletal proteins, was previously proposed to resemble eukaryotic intermediate filament (IF) proteins based on structural prediction and in vitro polymerization properties. Here, we demonstrate that crescentin...

  14. 42 CFR 422.752 - Basis for imposing intermediate sanctions and civil money penalties.

    Science.gov (United States)

    2010-10-01

    ... money penalties. 422.752 Section 422.752 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES... Sanctions § 422.752 Basis for imposing intermediate sanctions and civil money penalties. (a) All... sanctions at 422.750(a)(1) and (a)(3). (c) Civil Money Penalties. (1) CMS. In addition to, or in place of...

  15. Coronal mass ejection shock fronts containing the two types of intermediate shocks

    International Nuclear Information System (INIS)

    Steinolfson, R.S.; Hundhausen, A.J.

    1990-01-01

    Numerical solutions of the time-dependent, magnetohydrodynamic (MHD) equations in two dimensions are used to demonstrate the formation of both types of intermediate shocks in a single shock front for physical conditions that are an idealization of those expected to occur in some observed coronal mass ejections. The key to producing such a shock configuration in the simulations is the use of an initial atmosphere containing a magnetic field representative of that in a coronal streamer with open field lines overlying a region of closed field lines. Previous attempts using just open field lines (perpendicular to the surface) produced shock configurations containing just one of the two intermediate shock types. A schematic of such a shock front containing both intermediate shock types has been constructed previously based solely on the known properties of MHD shocks from the Rankine-Hugoniot equations and specific requirements placed on the shock solution at points along the front where the shock normal and upstream magnetic field are aligned. The shock front also contains, at various locations along the front, a hydrodynamic (nonmagnetic) shock, a switch-on shock, and a fast shock in addition to the intermediate shocks. This particular configuration occurs when the shock front speed exceeds the upstream (preshock) intermediate wave speed but is less than a critical speed defined in the paper (equation 1) along at least some portion of the shock front. A distinctive feature of the front is that it is concave upward (away from the surface) near the region where the field in the preshock plasma is normal to the front of near the central portion of the shock front

  16. Policies and Processes for Social Inclusion: Using EquiFrame and EquIPP for Policy Dialogue Comment on "Are Sexual and Reproductive Health Policies Designed for All? Vulnerable Groups in Policy Documents of Four European Countries and Their Involvement in Policy Development".

    Science.gov (United States)

    MacLachlan, Malcolm; Mannan, Hasheem; Huss, Tessy; Munthali, Alister; Amin, Mutamad

    2015-11-16

    The application of EquiFrame in the analysis of sexual and reproductive health policies by Ivanova et al to a new thematic area, their selection of only some of the Core Concepts of human rights in health service provision and the addition of new vulnerable groups relevant to the purpose of their analysis, are all very welcome developments. We also applaud their application of EquiFrame to policies in countries where it has not previously been used, along with their use of interviews with policy-makers to produce a deeper understanding of policy processes. We argue that clear justification for the inclusion of additional, or replacement of some exiting vulnerable groups within EquiFrame should be accompanied by clear definitions of such groups, along with the evidence-base that justifies their classification as a vulnerable or marginalised group. To illustrate the versatility of EquiFrame, we summarise a range of ways in which it has been used across a number of regions; including a brief Case Study of its use to develop the National Health Policy of Malawi. While EquiFrame focuses on policy content, we preview a new policy analysis tool - Equity and Inclusion in Policy Processes (EquIPP) - which assesses the extent of equity and inclusion in broader policy processes. Together, EquiFrame and EquIPP can be used to help governments and civil society ensure that policies are addressing the much stronger emphasis on social inclusion, now apparent in the Sustainable Development Goals (SDGs). © 2016 by Kerman University of Medical Sciences.

  17. Proton and Electron Additions to Iron (II) Dinitrogen Complexes Containing Pendant Amines

    Energy Technology Data Exchange (ETDEWEB)

    Heiden, Zachariah M.; Chen, Shentan; Labios, Liezel AN; Bullock, R. Morris; Walter, Eric D.; Tyson, Elizabeth L.; Mock, Michael T.

    2014-03-10

    We describe a single site cis-(H)FeII-N2 complex, generated by the protonation of an iron-carbon bond of a "reduced" iron complex, that models key aspects of proposed protonated intermediates of the E4 state of nitrogenase. The influence on N2 binding from the addition of protons to the pendant amine sites in the second coordination sphere is described. Furthermore, the addition of electrons to the protonated complexes results in H2 loss. The mechanism of H2 loss is explored to draw a parallel to the origin of H2 loss (homolytic or heterolytic) and the nature of N2 coordination in intermediates of the E4 state of nitrogenase.

  18. Input-output analysis of alternative policies implemented on the energy activities: An application for Catalonia

    International Nuclear Information System (INIS)

    Llop, Maria; Pie, Laia

    2008-01-01

    The aim of this paper is to analyze the economic impact of alternative policies implemented on the energy activities of the Catalan production system. Specifically, we analyze the effects of a tax on intermediate energy uses, a reduction in intermediate energy demand, and a tax on intermediate uses combined with a reduction in intermediate energy demand. The methodology involves two versions of the input-output price model: a competitive price formulation and a mark-up price formulation. The input-output price framework will make it possible to evaluate how the alternative measures modify production prices, consumption prices, private real income, and intermediate energy uses. The empirical application is for the Catalan economy and uses economic data for the year 2001. The combination of a tax on energy uses and an improvement in the energy efficiency of the production system is a measure that accomplishes both economic and environmental goals, since it has no effects on prices, it has a positive effect on private real income and, finally, energy consumption is considerably reduced. (author)

  19. Present status of intermediate band solar cell research

    International Nuclear Information System (INIS)

    Cuadra, L.; Marti, A.; Luque, A.

    2004-01-01

    The intermediate band solar cell is a theoretical concept with the potential for exceeding the performance of conventional single-gap solar cells. This novel photovoltaic converter bases its superior theoretical efficiency over single-gap solar cells by enhancing its photogenerated current, via the two-step absorption of sub-band gap photons, without reducing its output voltage. This is achieved through a material with an electrically isolated and partially filled intermediate band located within a higher forbidden gap. This material is commonly named intermediate band material. This paper centres on summarising the present status of intermediate band solar cell research. A number of attempts, which aim to implement the intermediate band concept, are being followed: the direct engineering of the intermediate band material, its implementation by means of quantum dots and the highly porous material approach. Among other sub-band gap absorbing proposals, there is a renewed interest on the impurity photovoltaic effect, the quantum well solar cells and the particularly promising proposal for the use of up- and down-converters

  20. Septic tank additive impacts on microbial populations.

    Science.gov (United States)

    Pradhan, S; Hoover, M T; Clark, G H; Gumpertz, M; Wollum, A G; Cobb, C; Strock, J

    2008-01-01

    Environmental health specialists, other onsite wastewater professionals, scientists, and homeowners have questioned the effectiveness of septic tank additives. This paper describes an independent, third-party, field scale, research study of the effects of three liquid bacterial septic tank additives and a control (no additive) on septic tank microbial populations. Microbial populations were measured quarterly in a field study for 12 months in 48 full-size, functioning septic tanks. Bacterial populations in the 48 septic tanks were statistically analyzed with a mixed linear model. Additive effects were assessed for three septic tank maintenance levels (low, intermediate, and high). Dunnett's t-test for tank bacteria (alpha = .05) indicated that none of the treatments were significantly different, overall, from the control at the statistical level tested. In addition, the additives had no significant effects on septic tank bacterial populations at any of the septic tank maintenance levels. Additional controlled, field-based research iswarranted, however, to address additional additives and experimental conditions.

  1. Evidence for a Shared Mechanism in the Formation of Urea-Induced Kinetic and Equilibrium Intermediates of Horse Apomyoglobin from Ultrarapid Mixing Experiments

    Science.gov (United States)

    Mizukami, Takuya; Abe, Yukiko; Maki, Kosuke

    2015-01-01

    In this study, the equivalence of the kinetic mechanisms of the formation of urea-induced kinetic folding intermediates and non-native equilibrium states was investigated in apomyoglobin. Despite having similar structural properties, equilibrium and kinetic intermediates accumulate under different conditions and via different mechanisms, and it remains unknown whether their formation involves shared or distinct kinetic mechanisms. To investigate the potential mechanisms of formation, the refolding and unfolding kinetics of horse apomyoglobin were measured by continuous- and stopped-flow fluorescence over a time range from approximately 100 μs to 10 s, along with equilibrium unfolding transitions, as a function of urea concentration at pH 6.0 and 8°C. The formation of a kinetic intermediate was observed over a wider range of urea concentrations (0–2.2 M) than the formation of the native state (0–1.6 M). Additionally, the kinetic intermediate remained populated as the predominant equilibrium state under conditions where the native and unfolded states were unstable (at ~0.7–2 M urea). A continuous shift from the kinetic to the equilibrium intermediate was observed as urea concentrations increased from 0 M to ~2 M, which indicates that these states share a common kinetic folding mechanism. This finding supports the conclusion that these intermediates are equivalent. Our results in turn suggest that the regions of the protein that resist denaturant perturbations form during the earlier stages of folding, which further supports the structural equivalence of transient and equilibrium intermediates. An additional folding intermediate accumulated within ~140 μs of refolding and an unfolding intermediate accumulated in <1 ms of unfolding. Finally, by using quantitative modeling, we showed that a five-state sequential scheme appropriately describes the folding mechanism of horse apomyoglobin. PMID:26244984

  2. Third O2 addition reactions promote the low-temperature auto-ignition of n-alkanes

    KAUST Repository

    Wang, Zhandong; Sarathy, Mani

    2016-01-01

    kinetic mechanism is considered. The advanced combustion phasing is initiated by the formation and destruction of additional radical chain-branching intermediates produced in the third O2 addition process, e.g. keto-dihydroperoxides and/or keto

  3. HIV-1 Env trimer opens through an asymmetric intermediate in which individual protomers adopt distinct conformations.

    Science.gov (United States)

    Ma, Xiaochu; Lu, Maolin; Gorman, Jason; Terry, Daniel S; Hong, Xinyu; Zhou, Zhou; Zhao, Hong; Altman, Roger B; Arthos, James; Blanchard, Scott C; Kwong, Peter D; Munro, James B; Mothes, Walther

    2018-03-21

    HIV-1 entry into cells requires binding of the viral envelope glycoprotein (Env) to receptor CD4 and coreceptor. Imaging of individual Env molecules on native virions shows Env trimers to be dynamic, spontaneously transitioning between three distinct well-populated conformational states: a pre-triggered Env (State 1), a default intermediate (State 2) and a three-CD4-bound conformation (State 3), which can be stabilized by binding of CD4 and coreceptor-surrogate antibody 17b. Here, using single-molecule Fluorescence Resonance Energy Transfer (smFRET), we show the default intermediate configuration to be asymmetric, with individual protomers adopting distinct conformations. During entry, this asymmetric intermediate forms when a single CD4 molecule engages the trimer. The trimer can then transition to State 3 by binding additional CD4 molecules and coreceptor.

  4. Comparative estimates of risks arising from storage of intermediate level radioactive wastes

    International Nuclear Information System (INIS)

    Moore, D.

    1986-04-01

    Estimates are presented of risks arising from accidents occuring during storage of nine types of conditioned intermediate level waste. Additional data are introduced relating to the risks from accidents affecting raw waste, and to risks associated with the occupational doses received during normal operation of a waste store. Risks in all three categories are shown to be extremely small. (author)

  5. Glutamate Induced Thermal Equilibrium Intermediate and Counteracting Effect on Chemical Denaturation of Proteins.

    Science.gov (United States)

    Anumalla, Bramhini; Prabhu, N Prakash

    2018-01-25

    When organisms are subjected to stress conditions, one of their adaptive responses is accumulation of small organic molecules called osmolytes. These osmolytes affect the structure and stability of the biological macromolecules including proteins. The present study examines the effect of a negatively charged amino acid osmolyte, glutamate (Glu), on two model proteins, ribonuclease A (RNase A) and α-lactalbumin (α-LA), which have positive and negative surface charges at pH 7, respectively. These proteins follow two-state unfolding transitions during both heat and chemical induced denaturation processes. The addition of Glu stabilizes the proteins against temperature and induces an early equilibrium intermediate during unfolding. The stability is found to be enthalpy-driven, and the free energy of stabilization is more for α-LA compared to RNase A. The decrease in the partial molar volume and compressibility of both of the proteins in the presence of Glu suggests that the proteins attain a more compact state through surface hydration which could provide a more stable conformation. This is also supported by molecule dynamic simulation studies which demonstrate that the water density around the proteins is increased upon the addition of Glu. Further, the intermediates could be completely destabilized by lower concentrations (∼0.5 M) of guanidinium chloride and salt. However, urea subverts the Glu-induced intermediate formed by α-LA, whereas it only slightly destabilizes in the case of RNase A which has a positive surface charge and could possess charge-charge interactions with Glu. This suggests that, apart from hydration, columbic interactions might also contribute to the stability of the intermediate. Gdm-induced denaturation of RNase A and α-LA in the absence and the presence of Glu at different temperatures was carried out. These results also show the Glu-induced stabilization of both of the proteins; however, all of the unfolding transitions followed two

  6. Photocatalytic oxidation of polycyclic aromatic hydrocarbons: Intermediates identification and toxicity testing

    International Nuclear Information System (INIS)

    Woo, O.T.; Chung, W.K.; Wong, K.H.; Chow, Alex T.; Wong, P.K.

    2009-01-01

    Polycyclic aromatic hydrocarbons (PAHs) are hydrophobic pollutants and their low water solubility limits their degradation in aqueous solution. The presence of water-miscible solvent such as acetone can increase the water solubility of PAHs, however acetone will also affect the degradation of PAH. In this study the effects of acetone on the photocatalytic degradation efficiency and pathways of 5 selected PAHs, namely naphthalene (2 rings), acenaphthylene (3 rings), phenanthrene (3 rings), anthracene (3 rings) and benzo[a]anthracene (4 rings) were investigated. The Microtox toxicity test was used to determine whether the PCO system can completely detoxify the parental PAHs and its intermediates. The addition of 16% acetone can greatly alter the degradation pathway of naphthalene and anthracene. Based on intermediates identified from degradation of the 5 PAHs, the location of parental PAHs attacked by reactive free radicals can be correlated with the localization energies of different positions of the compound. For toxicity analysis, irradiation by UV light was found to induce acute toxicity by generating intermediates/degradation products from PAHs and possibly acetone. Lastly, all PAHs (10 mg l -1 ) can be completely detoxified by titanium dioxide (100 mg l -1 ) within 24 h under UVA irradiation (3.9 mW cm -2 ).

  7. Optimal Maintenance of a Production System with Intermediate Buffers

    Directory of Open Access Journals (Sweden)

    Constantinos C. Karamatsoukis

    2012-01-01

    Full Text Available We consider a production-inventory system that consists of an input-generating installation, a production unit and L intermediate buffers. It is assumed that the installation transfers the raw material to buffer and the production unit pulls the raw material from buffer We consider the problem of the optimal preventive maintenance of the installation if the installation deteriorates stochastically with usage and the production unit is always in operative condition. We also consider the problem of the optimal preventive maintenance of the production unit if the production unit deteriorates stochastically with usage and the installation is always in operative condition. Under a suitable cost structure and for given contents of the buffers, it is proved that the average-cost optimal policy for the first (second problem initiates a preventive maintenance of the installation (production unit if and only if the degree of deterioration of the installation (production unit exceeds some critical level. Numerical results are presented for both problems.

  8. Features and safety aspects of Additional Waste Tank Farm, Tarapur

    International Nuclear Information System (INIS)

    Pradhan, Sanjay; Dubey, K.; Qureshi, F.T.; Lokeswar, S.P.

    2017-01-01

    Additional Waste Tank Farm (AWTF) at Tarapur is designed to store High and Intermediate Level Liquid wastes generated on an interim basis prior to treatment at TWMP for final disposal. Defence-in-depth philosophy is adopted in the design of AWTF

  9. Associations of Systemic Diseases with Intermediate Uveitis.

    Science.gov (United States)

    Shoughy, Samir S; Kozak, Igor; Tabbara, Khalid F

    2016-01-01

    To determine the associations of systemic diseases with intermediate uveitis. The medical records of 50 consecutive cases with intermediate uveitis referred to The Eye Center in Riyadh, Saudi Arabia, were reviewed. Age- and sex-matched patients without uveitis served as controls. Patients had complete ophthalmic and medical examinations. There were 27 male and 23 female patients. Mean age was 29 years with a range of 5-62 years. Overall, 21 cases (42%) had systemic disorders associated with intermediate uveitis and 29 cases (58%) had no associated systemic disease. A total of 11 patients (22%) had asthma, 4 (8%) had multiple sclerosis, 3 (6%) had presumed ocular tuberculosis, 1 (2%) had inflammatory bowel disease, 1 (2%) had non-Hodgkin lymphoma and 1 (2%) had sarcoidosis. Evidence of systemic disease was found in 50 (5%) of the 1,000 control subjects. Bronchial asthma was found in 37 patients (3.7 %), multiple sclerosis in 9 patients (0.9%), inflammatory bowel disease in 3 patients (0.3%), and tuberculosis in 1 patient (0.1%). None of the control patients had sarcoidosis or lymphoma. There were statistically significant associations between intermediate uveitis and bronchial asthma (p = 0.0001), multiple sclerosis (p = 0.003) and tuberculosis (p = 0.0005). Bronchial asthma and multiple sclerosis were the most frequently encountered systemic diseases associated with intermediate uveitis in our patient population. Patients with intermediate uveitis should undergo careful history-taking and investigations to rule out associated systemic illness.

  10. Exploring the chemical kinetics of partially oxidized intermediates by combining experiments, theory, and kinetic modeling.

    Science.gov (United States)

    Hoyermann, Karlheinz; Mauß, Fabian; Olzmann, Matthias; Welz, Oliver; Zeuch, Thomas

    2017-07-19

    Partially oxidized intermediates play a central role in combustion and atmospheric chemistry. In this perspective, we focus on the chemical kinetics of alkoxy radicals, peroxy radicals, and Criegee intermediates, which are key species in both combustion and atmospheric environments. These reactive intermediates feature a broad spectrum of chemical diversity. Their reactivity is central to our understanding of how volatile organic compounds are degraded in the atmosphere and converted into secondary organic aerosol. Moreover, they sensitively determine ignition timing in internal combustion engines. The intention of this perspective article is to provide the reader with information about the general mechanisms of reactions initiated by addition of atomic and molecular oxygen to alkyl radicals and ozone to alkenes. We will focus on critical branching points in the subsequent reaction mechanisms and discuss them from a consistent point of view. As a first example of our integrated approach, we will show how experiment, theory, and kinetic modeling have been successfully combined in the first infrared detection of Criegee intermediates during the gas phase ozonolysis. As a second example, we will examine the ignition timing of n-heptane/air mixtures at low and intermediate temperatures. Here, we present a reduced, fuel size independent kinetic model of the complex chemistry initiated by peroxy radicals that has been successfully applied to simulate standard n-heptane combustion experiments.

  11. Comparative TEA for Indirect Liquefaction Pathways to Distillate-Range Fuels via Oxygenated Intermediates

    Energy Technology Data Exchange (ETDEWEB)

    Tan, Eric; Snowden-Swan, Lesley J.; Talmadge, Michael; Dutta, Abhijit; Jones, Susanne; Ramasamy, Karthikeyan; Gray, Michael; Dagle, Robert; Padmaperuma, Asanga; Gerber, Mark; Sahir, Asad; Tao, Ling; Zhang, Yanan

    2017-03-03

    This paper presents a comparative techno-economic analysis of five conversion pathways from biomass to gasoline-, jet-, and diesel-range hydrocarbons via indirect liquefaction with specific focus on pathways utilizing oxygenated intermediates (derived either via thermochemical or biochemical conversion steps). The four emerging pathways of interest are compared with one conventional pathway (Fischer-Tropsch) for the production of the hydrocarbon blendstocks. The processing steps of the four emerging pathways include: biomass-to-syngas via indirect gasification, gas cleanup, conversion of syngas to alcohols/oxygenates, followed by conversion of alcohols/oxygenates to hydrocarbon blendstocks via dehydration, oligomerization, and hydrogenation. We show that the emerging pathways via oxygenated intermediates have the potential to be cost competitive with the conventional Fischer-Tropsch process. The evaluated pathways and the benchmark process generally exhibit similar fuel yields and carbon conversion efficiencies. The resulting minimum fuel selling prices are comparable to the benchmark at approximately $3.60 per gallon-gasoline equivalent, with potential for two new pathways to be more economically competitive. Additionally, the coproduct values can play an important role in the economics of the processes with oxygenated intermediates derived via syngas fermentation. Major cost drivers for the integrated processes are tied to achievable fuel yields and conversion efficiency of the intermediate steps, i.e., the production of oxygenates/alcohols from syngas and the conversion of oxygenates/alcohols to hydrocarbon fuels.

  12. [Latin-American public policy regarding social determinants of health].

    Science.gov (United States)

    García-Ramírez, Jorge A; Vélez-Álvarez, Consuelo

    2013-01-01

    The study was aimed at identifying Latin-American countries' public policy which has been related to the social determinants of health. A topic review was thus made of papers kept in the 22 Latin-American countries' databases and official documents issued by their multilateral organisations and ministries of health. The World Health Organization's concept of the social determinants of health has been summarised and a history given of the pertinent work developed worldwide in regions such as Europe and Latin-America. Public policy regarding the field of study in Argentina, Brazil, Bolivia, Chile, Colombia, Costa Rica, México and Venezuela has been described. It was concluded that Latin-America provides a panorama of inequality regarding the application of policy concerning the social determinants of health and that there was segmented intervention, mainly regarding intermediate determinants of health, without taking an integrated approach from different entrance points into account, according to the stated conceptual framework.

  13. "In the Wake of the Crisis : Leading Economists Reassess Economic Policy" Edited by Olivier Blanchard, David Romer, Michael Spence, and Joseph Stiglitz

    OpenAIRE

    Murat Ungor

    2013-01-01

    To understand the issues raised by the recent global crisis, IMF organized a conference on March 7-8, 2011, around six themes: monetary policy, fiscal policy, financial intermediation and regulation, capital account management, growth strategies, and the international monetary system. The conference proceedings are published in a book, In the Wake of the Crisis: Leading Economists Reassess Economic Policy. This review presents a summary of the book and provides its implications for research a...

  14. Intermediate Temperature Steam Electrolysis with Phosphate-Based Electrolytes

    DEFF Research Database (Denmark)

    Prag, Carsten Brorson

    as the technological issues and challenges faced. A setup suitable for intermediate temperature electrolysis has been constructed in order to accommodate testing in the IT region. This included the evaluation of multiple generations of components such as end plates and flow plates. Chemical vapour deposition...... treatment step of the synthesis. It was found that initial heating of the synthesis precursors to 270 _C gave a high quality sample in a reproducible fashion. Investigations of two additional novel phosphates was attempted. These were phosphoric acid treated Nb5P7O30 and a mixture of Bi2P4O13, BiPO4 and 2...

  15. 7 CFR 29.2 - Policy statement.

    Science.gov (United States)

    2010-01-01

    ... INSPECTION Policy Statement and Regulations Governing the Extension of Tobacco Inspection and Price Support Services to New Markets and to Additional Sales on Designated Markets § 29.2 Policy statement. Inspection... 7 Agriculture 2 2010-01-01 2010-01-01 false Policy statement. 29.2 Section 29.2 Agriculture...

  16. an intermediate moisture meat

    African Journals Online (AJOL)

    STORAGESEVER

    2008-07-04

    Jul 4, 2008 ... traditional SM muscle without compromising quality. ... technique is intermediate moisture food processing. ... Traditionally, most tsire suya producers use ..... quality of Chinese purebred and European X Chinese crossbred ...

  17. Isospin effects in intermediate energy heavy ion collision

    International Nuclear Information System (INIS)

    Liu Jianye; Zuo Wei; Yang Yanfang; Zhao Qiang; Guo Wenjun

    2001-01-01

    Based on the achievements for the intermediate energy heavy ion collision in authors' recent work and the progresses in the world, the isospin effects and the dependence of the entrance channel conditions on them in the intermediate energy heavy ion collisions were introduced, analysed and commended. From the calculation results by using isospin dependence quantum molecular dynamics, it is clear to see that the nuclear stopping power strongly depends on the in-medium isospin dependence nucleon-nucleon cross section and weakly on the symmetry potential in the energy region from about Fermi energy to 150 MeV/u and the intermediate mass fragment multiplicity also sensitively depends on the in-medium isospin dependent nucleon-nucleon cross section and weakly on the symmetry potential in a selected energy region. But the preequilibrium emission neutron-proton ratio is quite contrary, it sensitively depends on the symmetry potential and weakly on the in-medium isospin dependent nucleon-nucleon cross section. In addition to the nuclear stopping sensitively depending on the beam energy, impact parameter and the mass of colliding system and weakly on the neutron-proton ratio of the colliding systems with about the same mass, the preequilibrium emission neutron-neutron ratio sensitively depends on the beam energy and the neutron-proton ratio of colliding system, but weakly on the impact parameter. From above results it is proposed that the nuclear stopping is a new probe to extract the information on the in-medium isospin dependence nucleon-nucleon cross section in energy region from about Fermi energy to 150 MeV/u and the preequilibrium emission neutron-proton ratio is a good probe for extracting the information about the symmetry potential from the lower energy to about 150 MeV/u

  18. Incremental value of contrast myocardial perfusion to detect intermediate versus severe coronary artery stenosis during stress-echocardiography

    Directory of Open Access Journals (Sweden)

    Ugo Fabrizio

    2010-05-01

    Full Text Available Abstract Background We aimed to compare the incremental value of contrast myocardial perfusion imaging (MPI for the detection of intermediate versus severe coronary artery stenosis during dipyridamole-atropine echocardiography (DASE. Wall motion (WM assessment during stress-echocardiography demonstrates suboptimal sensitivity to detect coronary artery disease (CAD, particularly in patients with isolated intermediate (50%-70% coronary stenosis. Methods We performed DASE with MPI in 150 patients with a suspected chest pain syndrome who were given clinical indication to coronary angiography. Results and discussion When CAD was defined as the presence of a ≥50% stenosis, the addition of MPI increased sensitivity (+30% and decreased specificity (-14%, with a final increase in total diagnostic accuracy (+16%, p Conclusions The addition of MPI on top of WM analysis during DASE increases the diagnostic sensitivity to detect obstructive CAD, whatever its definition (≥50% or > 70% stenosis, but it is mainly driven by the sensitivity increase in the intermediate group (50%-70% stenosis. The total diagnostic accuracy increased only when defining CAD as ≥50% stenosis, since in patients with severe stenosis (> 70% the decrease in specificity is not counterbalanced by the minor sensitivity increase.

  19. Clinical Evaluation of Functional Vision of +1.5 Diopters near Addition, Aspheric, Rotational Asymmetric Multifocal Intraocular Lens.

    Science.gov (United States)

    Kretz, Florian Tobias Alwin; Khoramnia, Rahmin; Attia, Mary Safwat; Koss, Michael Janusz; Linz, Katharina; Auffarth, Gerd Uwe

    2016-10-01

    To evaluate postoperative outcomes and visual performance in intermediate distance after implantation of a +1.5 diopters (D) addition, aspheric, rotational asymmetric multifocal intraocular lens (MIOL). Patients underwent bilateral cataract surgery with implantation of an aspheric, asymmetric MIOL with +1.5 D near addition. A complete ophthalmological examination was performed preoperatively and 3 months postoperatively. The main outcome measures were monocular and binocular uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), uncorrected intermediate visual acuity (UIVA), distance corrected intermediate visual acuity (DCIVA), uncorrected near visual acuity (UNVA) and distance corrected keratometry, and manifest refraction. The Salzburg Reading Desk was used to analyze unilateral and bilateral functional vision with uncorrected and corrected reading acuity, reading distance, reading speed, and the smallest log-scaled print size that could be read effectively at near and intermediate distances. The study comprised 60 eyes of 30 patients (mean age, 68.30 ± 9.26 years; range, 34 to 80 years). There was significant improvement in UDVA and CDVA. Mean UIVA was 0.01 ± 0.09 logarithm of the minimum angle of resolution (logMAR) and mean DCIVA was -0.02 ± 0.11 logMAR. In Salzburg Reading Desk analysis for UIVA, the mean subjective intermediate distance was 67.58 ± 8.59 cm with mean UIVA of -0.02 ± 0.09 logMAR and mean word count of 96.38 ± 28.32 words/min. The new aspheric, asymmetric, +1.5 D near addition MIOL offers good results for distance visual function in combination with good performance for intermediate distances and functional results for near distance.

  20. COMMON FISCAL POLICY

    Directory of Open Access Journals (Sweden)

    Gabriel Mursa

    2014-08-01

    Full Text Available The purpose of this article is to demonstrate that a common fiscal policy, designed to support the euro currency, has some significant drawbacks. The greatest danger is the possibility of leveling the tax burden in all countries. This leveling of the tax is to the disadvantage of countries in Eastern Europe, in principle, countries poorly endowed with capital, that use a lax fiscal policy (Romania, Bulgaria, etc. to attract foreign investment from rich countries of the European Union. In addition, common fiscal policy can lead to a higher degree of centralization of budgetary expenditures in the European Union.

  1. Production of alien chromosome additions and their utility in plant genetics

    NARCIS (Netherlands)

    Chang, S.B.; Jong, de J.H.S.G.M.

    2005-01-01

    Breeding programs aiming at transferring desirable genes from one species to another through interspecific hybridization and backcrossings often produce monosomic and disomic additions as intermediate crossing products. Such aneuploids contain alien chromosomes added to the complements of the

  2. Optimal Monetary Policy with Durable Consumption Goods and Factor Demand Linkages

    DEFF Research Database (Denmark)

    Petrella, Ivan; Santoro, Emiliano

    of production in both sectors, according to an input-output matrix calibrated on the US economy. As shown in a number of recent contributions, this roundabout technology allows us to reconcile standard two-sector New Keynesian models with the empirical evidence showing co-movement between durable and non......-durable spending in response to a monetary policy shock. A main result of our monetary policy analysis is that strategic complementarities generated by factor demand linkages amplify social welfare loss. As the degree of interconnection between sectors increases, the cost of misperceiving the correct production......This paper deals with the implications of factor demand linkages for monetary policy design. We develop a dynamic general equilibrium model with two sectors that produce durable and non-durable goods, respectively. Part of the output produced in each sector is used as an intermediate input...

  3. Taxation of Financial Intermediation Activities in Hong Kong

    OpenAIRE

    Jack M. Mintz; Stephen R. Richardson

    2001-01-01

    This paper discusses issues related to the taxation of financial intermediation in Hong Kong in the context of Hong Kong's position as a major regional financial centre. It first provides some background analysis as to the definition of financial intermediation and identification of the providers of financial services. This is then followed by a discussion of the principles of taxation applicable to financial intermediation, including a comparison of income taxes to consumption taxes. Some sp...

  4. Energy damping and intermediate velocity fragment emission in peripheral Kr+Au collisions at 43 MeV/u

    International Nuclear Information System (INIS)

    Stuttge, L.; Adloff, J.C.; Bilwes, B.; Bilwes, R.; Cosmo, F.; Glaser, M.; Rudolf, G.; Scheibling, F.

    1991-01-01

    Triple and four-fold coincidences among fragments have been measured in the reaction 197 Au( 84 Kr,X) at 43 MeV/u. All events showing the projectile-like nucleus and fission fragments of the target-like nucleus, and all events with one additional intermediate velocity fragment, were analysed in the frame of a dissipative collision and a participant-spectator model. The mechanism is basically that of a dissipative collision but the emission of the intermediate velocity fragment by the target differs from an equilibrated evaporation. (author) 16 refs., 10 figs

  5. Intermediate-energy nuclear chemistry workshop

    International Nuclear Information System (INIS)

    Butler, G.W.; Giesler, G.C.; Liu, L.C.; Dropesky, B.J.; Knight, J.D.; Lucero, F.; Orth, C.J.

    1981-05-01

    This report contains the proceedings of the LAMPF Intermediate-Energy Nuclear Chemistry Workshop held in Los Alamos, New Mexico, June 23-27, 1980. The first two days of the Workshop were devoted to invited review talks highlighting current experimental and theoretical research activities in intermediate-energy nuclear chemistry and physics. Working panels representing major topic areas carried out indepth appraisals of present research and formulated recommendations for future research directions. The major topic areas were Pion-Nucleus Reactions, Nucleon-Nucleus Reactions and Nuclei Far from Stability, Mesonic Atoms, Exotic Interactions, New Theoretical Approaches, and New Experimental Techniques and New Nuclear Chemistry Facilities

  6. Intermediate-energy nuclear chemistry workshop

    Energy Technology Data Exchange (ETDEWEB)

    Butler, G.W.; Giesler, G.C.; Liu, L.C.; Dropesky, B.J.; Knight, J.D.; Lucero, F.; Orth, C.J.

    1981-05-01

    This report contains the proceedings of the LAMPF Intermediate-Energy Nuclear Chemistry Workshop held in Los Alamos, New Mexico, June 23-27, 1980. The first two days of the Workshop were devoted to invited review talks highlighting current experimental and theoretical research activities in intermediate-energy nuclear chemistry and physics. Working panels representing major topic areas carried out indepth appraisals of present research and formulated recommendations for future research directions. The major topic areas were Pion-Nucleus Reactions, Nucleon-Nucleus Reactions and Nuclei Far from Stability, Mesonic Atoms, Exotic Interactions, New Theoretical Approaches, and New Experimental Techniques and New Nuclear Chemistry Facilities.

  7. The ARES High-level Intermediate Representation

    Energy Technology Data Exchange (ETDEWEB)

    Moss, Nicholas David [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-03-03

    The LLVM intermediate representation (IR) lacks semantic constructs for depicting common high-performance operations such as parallel and concurrent execution, communication and synchronization. Currently, representing such semantics in LLVM requires either extending the intermediate form (a signi cant undertaking) or the use of ad hoc indirect means such as encoding them as intrinsics and/or the use of metadata constructs. In this paper we discuss a work in progress to explore the design and implementation of a new compilation stage and associated high-level intermediate form that is placed between the abstract syntax tree and when it is lowered to LLVM's IR. This highlevel representation is a superset of LLVM IR and supports the direct representation of these common parallel computing constructs along with the infrastructure for supporting analysis and transformation passes on this representation.

  8. Water activity reduction of intermediate moisture yellowstrip trevally (Selaroides leptolepis

    Directory of Open Access Journals (Sweden)

    Phomajun, P.

    2005-05-01

    Full Text Available Water activity reduction of intermediate moisture yellowstrip trevally was studied. The optimal time (8, 12, 16, 20 hrs. for curing marinade was investigated. The effects of different humectants (glycerol, sorbitol, lactitol, glucose syrup at 50% w/w of curing ingredients were compared. Results showed that moisture content and water activity of cured yellowstrip trevally decreased as curing time increased (p0.05. However, the hardness of intermediate moisture Yellowstrip trevally, determined by texture analyzer, decreased. Hardness, shear force, L a b value of sample added with various humectants were lower than those of the control (p0.05. The glycerol-added samples had the highest overall acceptability score and were higher than control, whereas the glucose syrup-added samples had the lowest score. Moisture content of the samples with the addition of various humectants was higher than that of the control (18.28 %. The samples added with glycerol retained the highest moisture (24.94%. The adsorption isotherm studies showed that the equilibrium moisture of sample added with glycerol was higher than that added with lactitol.

  9. Gasoline Engine Mechanics. Performance Objectives. Intermediate Course.

    Science.gov (United States)

    Jones, Marion

    Several intermediate performance objectives and corresponding criterion measures are listed for each of six terminal objectives presented in this curriculum guide for an intermediate gasoline engine mechanics course at the secondary level. (For the beginning course guide see CE 010 947.) The materials were developed for a two-semester (2 hour…

  10. Sustainable innovation policy advice using a policy watch approach to ‘policies’ mapping

    OpenAIRE

    Repo, Juha Petteri; Matschoss, Kaisa Johanna; Tregner-Mlinaric, Anita; Van Eynde, Sarah; Ramioul, Monique; Damianova, Zoya; Kozarev, Ventseslav

    2017-01-01

    This chapter illustrates via a piloted application how one of the five steps of the CASI Framework (CASI-F), which is designed for the management and assessment of sustainable innovation, can be applied to monitor policy developments. To this end, we reviewed 96 policy recommendations from CASI policy briefs concerning the Europe 2020 strategy, with a special focus on resource efficiency. The results show that CASI-F can provide a useful additional tool for analysing and reflecting on the out...

  11. Application of the photoreflectance technique to the characterization of quantum dot intermediate band materials for solar cells

    International Nuclear Information System (INIS)

    Canovas, E.; Marti, A.; Lopez, N.; Antolin, E.; Linares, P.G.; Farmer, C.D.; Stanley, C.R.; Luque, A.

    2008-01-01

    Intermediate band materials rely on the creation of a new electronic band within the bandgap of a conventional semiconductor that is isolated from the conduction and valence band by a true zero density of states. Due to the presence of the intermediate band, a solar cell manufactured using these materials is capable of producing additional photocurrent, thanks to the absorption of photons with energy lower than the conventional bandgap. In this respect, the characterization of these materials by suitable techniques becomes a key element in the development of the new photovoltaic devices called intermediate band solar cells. The technique of photoreflectance is particularly suited to this purpose because it is contact-less and allows the characterization of the material without the need of actually manufacturing a complete device. Using room temperature photoreflectance we have analyzed intermediate band materials based on quantum dots and have been able to identify the energy levels involved. Also, from the photoreflectance data we have demonstrated the overlap of the wave-functions defined by the quantum dots

  12. Intermediate tree cover can maximize groundwater recharge in the seasonally dry tropics

    Science.gov (United States)

    Ilstedt, U.; Bargués Tobella, A.; Bazié, H. R.; Bayala, J.; Verbeeten, E.; Nyberg, G.; Sanou, J.; Benegas, L.; Murdiyarso, D.; Laudon, H.; Sheil, D.; Malmer, A.

    2016-01-01

    Water scarcity contributes to the poverty of around one-third of the world’s people. Despite many benefits, tree planting in dry regions is often discouraged by concerns that trees reduce water availability. Yet relevant studies from the tropics are scarce, and the impacts of intermediate tree cover remain unexplored. We developed and tested an optimum tree cover theory in which groundwater recharge is maximized at an intermediate tree density. Below this optimal tree density the benefits from any additional trees on water percolation exceed their extra water use, leading to increased groundwater recharge, while above the optimum the opposite occurs. Our results, based on groundwater budgets calibrated with measurements of drainage and transpiration in a cultivated woodland in West Africa, demonstrate that groundwater recharge was maximised at intermediate tree densities. In contrast to the prevailing view, we therefore find that moderate tree cover can increase groundwater recharge, and that tree planting and various tree management options can improve groundwater resources. We evaluate the necessary conditions for these results to hold and suggest that they are likely to be common in the seasonally dry tropics, offering potential for widespread tree establishment and increased benefits for hundreds of millions of people. PMID:26908158

  13. Chemical intermediate detection following corona discharge on volatile organic compounds: general method using molecular beam techniques

    International Nuclear Information System (INIS)

    He Luning; Sulkes, Mark

    2011-01-01

    Nonthermal plasma (NTP)-based treatments of volatile organic compounds (VOCs) have potential for effective environmental remediation. Theory and experiment that consider the basic science pertaining to discharge events have helped improve NTP remediation outcomes. If direct information on early post-discharge chemical intermediates were also available, it would likely lead to additional improvement in NTP remediation outcomes. To this point, however, experiments yielding direct information on post-NTP VOC intermediates have been limited. An approach using supersonic expansion molecular beam methods offers general promise for detection of post-discharge VOC intermediates. To illustrate the potential utility of these methods, we present mass spectra showing the growth of early products formed when pulsed corona discharges were carried out on toluene in He and then in He with added O 2 . Good general detection of neutral post-discharge species was obtained using 800 nm 150 fs photoionization pulses.

  14. Mapping Intermediality in Performance

    NARCIS (Netherlands)

    2010-01-01

    Mapping Intermediality in Performance benadert het vraagstuk van intermedialiteit met betrekking tot performance (vooral theater) vanuit vijf verschillende invalshoeken: performativiteit en lichaam; tijd en ruimte; digitale cultuur en posthumanisme; netwerken; pedagogiek en praxis. In deze boeiende

  15. The transport implications of siting policies for the disposal of low-level radioactive wastes

    International Nuclear Information System (INIS)

    James, I.A.

    1986-01-01

    This report has been produced to be complementary to the previously issued report ''The Transport Implications of Regional Policies for The Disposal of Intermediate Level Radioactive Wastes''. The same combinations of disposal facilities have been used so that direct comparison with intermediate waste results can be made. Low level wastes and short-lived intermediate level wastes for near-surface disposal are assumed to share a common infrastructure on the rail system and hence a methodology of separating total costs between these two waste types has been derived. Two transport modes, road and rail have been analysed. Hybrid transport, a combination of road and rail systems, has not been examined since no site is considered to produce sufficient waste to justify a dedicated rail service. Sellafield, has not been included in this examination since it is assumed to be served by its own disposal site at Drigg. (author)

  16. Passing the ITIL V3 intermediate exams the study guide

    CERN Document Server

    Bernard, Pierre

    2011-01-01

    This book helps people prepare for the ITIL® Intermediate qualification exams. It contains tips for selecting the appropriate course, preparation and finally what trainers and examiners expect you to achieve during pre-exam training sessions. Additionally, this book covers tips on reading and understanding the syllabi, scenarios, supplemental information, and sample question and the answers.Written by a respected ITIL trainer and reviewed by other global professionals this unique work provides clear and concise guidance for all those seeking to build on the ITIL training they have received at

  17. Variable mycorrhizal benefits on the reproductive output of Geranium sylvaticum, with special emphasis on the intermediate phenotype.

    Science.gov (United States)

    Varga, S; Kytöviita, M-M

    2014-03-01

    In several gynodioecious species, intermediate sex between female and hermaphrodite has been reported, but few studies have investigated fitness parameters of this intermediate phenotype. Here, we examined the interactions between plant sex and arbuscular mycorrhizal (AM) fungal species affecting the reproductive output of Geranium sylvaticum, a sexually polymorphic plant species with frequent intermediate sexes between females and hermaphrodites, using a common garden experiment. Flowering phenology, AM colonisation levels and several plant vegetative and reproductive parameters, including seed and pollen production, were measured. Differences among sexes were detected in flowering, fruit set, pollen production and floral size. The two AM species used in the present work had different effects on plant fitness parameters. One AM species increased female fitness through increasing seed number and seed mass, while the other species reduced seed mass in all sexes investigated. AM fungi did not affect intermediate and hermaphrodite pollen content in anthers. The three sexes in G. sylvaticum did not differ in their reproductive output in terms of total seed production, but hermaphrodites had potentially larger fathering ability than intermediates due to higher anther number. The ultimate female function--seed production--did not differ among the sexes, but one of the AM fungi used potentially decreased host plant fitness. In addition, in the intermediate sex, mycorrhizal symbiosis functioned similarly in females as in hermaphrodites. © 2013 German Botanical Society and The Royal Botanical Society of the Netherlands.

  18. Real-time and high accuracy frequency measurements for intermediate frequency narrowband signals

    Science.gov (United States)

    Tian, Jing; Meng, Xiaofeng; Nie, Jing; Lin, Liwei

    2018-01-01

    Real-time and accurate measurements of intermediate frequency signals based on microprocessors are difficult due to the computational complexity and limited time constraints. In this paper, a fast and precise methodology based on the sigma-delta modulator is designed and implemented by first generating the twiddle factors using the designed recursive scheme. This scheme requires zero times of multiplications and only half amounts of addition operations by using the discrete Fourier transform (DFT) and the combination of the Rife algorithm and Fourier coefficient interpolation as compared with conventional methods such as DFT and Fast Fourier Transform. Experimentally, when the sampling frequency is 10 MHz, the real-time frequency measurements with intermediate frequency and narrowband signals have a measurement mean squared error of ±2.4 Hz. Furthermore, a single measurement of the whole system only requires approximately 0.3 s to achieve fast iteration, high precision, and less calculation time.

  19. The Impact of the Regional Policy on the European Economy

    Directory of Open Access Journals (Sweden)

    Romeo-Victor Ionescu

    2016-05-01

    Full Text Available Nowadays, EU28 operates in a very sensitive socio-economic environment. This is why the paper faces to the idea of changing the political approach in the EU. In order to support this idea, two essential common policies (Regional Policy and Cohesion Policy are analyzed, using pertinent indicators, as GDP per capita, gross value added and labor productivity. A comparative analysis covers EU28 and Euro area. On the other hand, the regional analysis points out the economic disparities between NUTS2 regions. The intermediate conclusions of the analysis led to a cluster approach for the Member States. Moreover, the forecasting procedures applied to the above three economic indicators led to the same idea: an EU more divided than integrated. The main conclusion of the paper is that the present economic approach has to be change into another focused on maintaining and, after that, decreasing the present European socio-economic disparities.

  20. The Intermediate Neutrino Program

    CERN Document Server

    Adams, C.; Ankowski, A.M.; Asaadi, J.A.; Ashenfelter, J.; Axani, S.N.; Babu, K.; Backhouse, C.; Band, H.R.; Barbeau, P.S.; Barros, N.; Bernstein, A.; Betancourt, M.; Bishai, M.; Blucher, E.; Bouffard, J.; Bowden, N.; Brice, S.; Bryan, C.; Camilleri, L.; Cao, J.; Carlson, J.; Carr, R.E.; Chatterjee, A.; Chen, M.; Chen, S.; Chiu, M.; Church, E.D.; Collar, J.I.; Collin, G.; Conrad, J.M.; Convery, M.R.; Cooper, R.L.; Cowen, D.; Davoudiasl, H.; de Gouvea, A.; Dean, D.J.; Deichert, G.; Descamps, F.; DeYoung, T.; Diwan, M.V.; Djurcic, Z.; Dolinski, M.J.; Dolph, J.; Donnelly, B.; Dwyer, D.A.; Dytman, S.; Efremenko, Y.; Everett, L.L.; Fava, A.; Figueroa-Feliciano, E.; Fleming, B.; Friedland, A.; Fujikawa, B.K.; Gaisser, T.K.; Galeazzi, M.; Galehouse, D.C.; Galindo-Uribarri, A.; Garvey, G.T.; Gautam, S.; Gilje, K.E.; Gonzalez-Garcia, M.; Goodman, M.C.; Gordon, H.; Gramellini, E.; Green, M.P.; Guglielmi, A.; Hackenburg, R.W.; Hackenburg, A.; Halzen, F.; Han, K.; Hans, S.; Harris, D.; Heeger, K.M.; Herman, M.; Hill, R.; Holin, A.; Huber, P.; Jaffe, D.E.; Johnson, R.A.; Joshi, J.; Karagiorgi, G.; Kaufman, L.J.; Kayser, B.; Kettell, S.H.; Kirby, B.J.; Klein, J.R.; Kolomensky, Yu. G.; Kriske, R.M.; Lane, C.E.; Langford, T.J.; Lankford, A.; Lau, K.; Learned, J.G.; Ling, J.; Link, J.M.; Lissauer, D.; Littenberg, L.; Littlejohn, B.R.; Lockwitz, S.; Lokajicek, M.; Louis, W.C.; Luk, K.; Lykken, J.; Marciano, W.J.; Maricic, J.; Markoff, D.M.; Martinez Caicedo, D.A.; Mauger, C.; Mavrokoridis, K.; McCluskey, E.; McKeen, D.; McKeown, R.; Mills, G.; Mocioiu, I.; Monreal, B.; Mooney, M.R.; Morfin, J.G.; Mumm, P.; Napolitano, J.; Neilson, R.; Nelson, J.K.; Nessi, M.; Norcini, D.; Nova, F.; Nygren, D.R.; Orebi Gann, G.D.; Palamara, O.; Parsa, Z.; Patterson, R.; Paul, P.; Pocar, A.; Qian, X.; Raaf, J.L.; Rameika, R.; Ranucci, G.; Ray, H.; Reyna, D.; Rich, G.C.; Rodrigues, P.; Romero, E.Romero; Rosero, R.; Rountree, S.D.; Rybolt, B.; Sanchez, M.C.; Santucci, G.; Schmitz, D.; Scholberg, K.; Seckel, D.; Shaevitz, M.; Shrock, R.; Smy, M.B.; Soderberg, M.; Sonzogni, A.; Sousa, A.B.; Spitz, J.; St. John, J.M.; Stewart, J.; Strait, J.B.; Sullivan, G.; Svoboda, R.; Szelc, A.M.; Tayloe, R.; Thomson, M.A.; Toups, M.; Vacheret, A.; Vagins, M.; Van de Water, R.G.; Vogelaar, R.B.; Weber, M.; Weng, W.; Wetstein, M.; White, C.; White, B.R.; Whitehead, L.; Whittington, D.W.; Wilking, M.J.; Wilson, R.J.; Wilson, P.; Winklehner, D.; Winn, D.R.; Worcester, E.; Yang, L.; Yeh, M.; Yokley, Z.W.; Yoo, J.; Yu, B.; Yu, J.; Zhang, C.

    2015-01-01

    The US neutrino community gathered at the Workshop on the Intermediate Neutrino Program (WINP) at Brookhaven National Laboratory February 4-6, 2015 to explore opportunities in neutrino physics over the next five to ten years. Scientists from particle, astroparticle and nuclear physics participated in the workshop. The workshop examined promising opportunities for neutrino physics in the intermediate term, including possible new small to mid-scale experiments, US contributions to large experiments, upgrades to existing experiments, R&D plans and theory. The workshop was organized into two sets of parallel working group sessions, divided by physics topics and technology. Physics working groups covered topics on Sterile Neutrinos, Neutrino Mixing, Neutrino Interactions, Neutrino Properties and Astrophysical Neutrinos. Technology sessions were organized into Theory, Short-Baseline Accelerator Neutrinos, Reactor Neutrinos, Detector R&D and Source, Cyclotron and Meson Decay at Rest sessions.This report summ...

  1. The application of contrast explanation to energy policy research: UK nuclear energy policy 2002–2012

    International Nuclear Information System (INIS)

    Heffron, Raphael J.

    2013-01-01

    This paper advances the application of the methodology, contrast explanation, to energy policy research. Research in energy policy is complex and often involves inter-disciplinary work, which traditional economic methodologies fail to capture. Consequently, the more encompassing methodology of contrast explanation is assessed and its use in other social science disciplines explored in brief. It is then applied to an energy policy research topic—in this case, nuclear energy policy research in the UK. Contrast explanation facilitates research into policy and decision-making processes in energy studies and offers an alternative to the traditional economic methods used in energy research. Further, contrast explanation is extended by the addition of contested and uncontested hypotheses analyses. This research focuses on the methods employed to deliver the new nuclear programme of the UK government. In order to achieve a sustainable nuclear energy policy three issues are of major importance: (1) law, policy and development; (2) public administration; and (3) project management. Further, the research identifies that policy in the area remains to be resolved, in particular at an institutional and legal level. However, contrary to the literature, in some areas, the research identifies a change of course as the UK concentrates on delivering a long-term policy for the nuclear energy sector and the overall energy sector. - Highlights: ► Energy policy research is interdisciplinary and needs additional methodological approaches. ► New method of contrast explanation advanced for energy policy research. ► This methodology is based on dialectical learning which examines conflict between sources of data. ► Research example used here is of UK nuclear energy policy. ► Major issues in UK nuclear energy policy are planning law, public administration, and project management

  2. Health financing for universal coverage and health system performance: concepts and implications for policy.

    Science.gov (United States)

    Kutzin, Joseph

    2013-08-01

    Unless the concept is clearly understood, "universal coverage" (or universal health coverage, UHC) can be used to justify practically any health financing reform or scheme. This paper unpacks the definition of health financing for universal coverage as used in the World Health Organization's World health report 2010 to show how UHC embodies specific health system goals and intermediate objectives and, broadly, how health financing reforms can influence these. All countries seek to improve equity in the use of health services, service quality and financial protection for their populations. Hence, the pursuit of UHC is relevant to every country. Health financing policy is an integral part of efforts to move towards UHC, but for health financing policy to be aligned with the pursuit of UHC, health system reforms need to be aimed explicitly at improving coverage and the intermediate objectives linked to it, namely, efficiency, equity in health resource distribution and transparency and accountability. The unit of analysis for goals and objectives must be the population and health system as a whole. What matters is not how a particular financing scheme affects its individual members, but rather, how it influences progress towards UHC at the population level. Concern only with specific schemes is incompatible with a universal coverage approach and may even undermine UHC, particularly in terms of equity. Conversely, if a scheme is fully oriented towards system-level goals and objectives, it can further progress towards UHC. Policy and policy analysis need to shift from the scheme to the system level.

  3. Two-step digit-set-restricted modified signed-digit addition-subtraction algorithm and its optoelectronic implementation.

    Science.gov (United States)

    Qian, F; Li, G; Ruan, H; Jing, H; Liu, L

    1999-09-10

    A novel, to our knowledge, two-step digit-set-restricted modified signed-digit (MSD) addition-subtraction algorithm is proposed. With the introduction of the reference digits, the operand words are mapped into an intermediate carry word with all digits restricted to the set {1, 0} and an intermediate sum word with all digits restricted to the set {0, 1}, which can be summed to form the final result without carry generation. The operation can be performed in parallel by use of binary logic. An optical system that utilizes an electron-trapping device is suggested for accomplishing the required binary logic operations. By programming of the illumination of data arrays, any complex logic operations of multiple variables can be realized without additional temporal latency of the intermediate results. This technique has a high space-bandwidth product and signal-to-noise ratio. The main structure can be stacked to construct a compact optoelectronic MSD adder-subtracter.

  4. The Limit of Public Policy : Endogenous Preferences

    NARCIS (Netherlands)

    Bar-Gill, O.; Fershtman, C.

    2000-01-01

    In designing public policy it is not enough to consider the possible reaction of individuals to the chosen policy.Public policy may also affect the formation of preferences and norms in a society.The endogenous evolution of preferences, in addition to introducing a conceptual difficulty in

  5. Intermediate Inflation or Late Time Acceleration?

    International Nuclear Information System (INIS)

    Sanyal, A.K.

    2008-01-01

    The expansion rate of intermediate inflation lies between the exponential and power law expansion but corresponding accelerated expansion does not start at the onset of cosmological evolution. Present study of intermediate inflation reveals that it admits scaling solution and has got a natural exit form it at a later epoch of cosmic evolution, leading to late time acceleration. The corresponding scalar field responsible for such feature is also found to behave as a tracker field for gravity with canonical kinetic term.

  6. On financial equilibrium with intermediation costs

    DEFF Research Database (Denmark)

    Markeprand, Tobias Ejnar

    2008-01-01

    This paper studies the set of competitive equilibria in financial economies with intermediation costs. We consider an arbitrary dividend structure, which includes options and equity with limited liabilities.We show a general existence result and upper-hemi continuity of the equilibrium correspond......This paper studies the set of competitive equilibria in financial economies with intermediation costs. We consider an arbitrary dividend structure, which includes options and equity with limited liabilities.We show a general existence result and upper-hemi continuity of the equilibrium...

  7. Intermediate product selection and blending in the food processing industry

    DEFF Research Database (Denmark)

    Kilic, Onur A.; Akkerman, Renzo; van Donk, Dirk Pieter

    2013-01-01

    This study addresses a capacitated intermediate product selection and blending problem typical for two-stage production systems in the food processing industry. The problem involves the selection of a set of intermediates and end-product recipes characterising how those selected intermediates...

  8. The environmental policy of the EC. An analysis exemplified by air pollution abatement policy

    International Nuclear Information System (INIS)

    Caspari, S.

    1995-01-01

    Since the early seventies the European Community has reacted to increasing ecological damage with complex and comprehensive common environmental policies. In this study, the author analyzes and evaluates the theoretical conception and the instrumental application of the EC Environmental Policy using four criteria: (1) Ecological effectiveness, (2) economic efficiency, (3) conformity with a market order - viewpoint of 'Ordnungspolitik', (4) 'sustainability'. The study shows that there is a large discrepancy between the demands and the reality of the EC Environmental Policy. In addition to grave ecological deficiencies it reveals an increse in rent-seeking activities and an interventionist trend which have resulted in the erosion of the competitive incentive system of the market order in the Community. In view of various deficits the author perceives a basic 'regulation paradox' and a 'policy failure'. Based on a diagnosis of the causes of these deficiencies, he outlines some proposals for a reform of the EC Environmental Policy, indicating that a central prerequisite for a more effective and efficient environmental protection is a reorientation in the system ('Ordnungspolitik') which determines the common Environmental Policy. In addition, he maintains that in view of the clear asymmetry in the representation of interests in favour of particularist interests it is necessary to strengthen public interest in order to enable a more effective protection of the options future generations will have regarding their lives and their behaviour. (orig.) [de

  9. Improving Staffing and Nurse Engagement in a Neuroscience Intermediate Unit.

    Science.gov (United States)

    Nadolski, Charles; Britt, Pheraby; Ramos, Leah C

    2017-06-01

    The neuroscience intermediate unit is a 23-bed unit that was initially staffed with a nurse-to-patient ratio of 1:4 to 1:5. In time, the unit's capacity to care for the exceeding number of progressively acute patients fell short of the desired goals in the staff affecting the nurse satisfaction. The clinical nurses desired a lower nurse-patient ratio. The purpose of this project was to justify a staffing increase through a return on investment and increased quality metrics. This initiative used mixed methodology to determine the ideal staffing for a neuroscience intermediate unit. The quantitative section focused on a review of the acuity of the patients. The qualitative section was based on descriptive interviews with University Healthcare Consortium nurse managers from similar units. The study reviewed the acuity of 9,832 patient days to determine the accurate acuity of neuroscience intermediate unit patients. Nurse managers at 12 University Healthcare Consortium hospitals and 8 units at the Medical University of South Carolina were contacted to compare staffing levels. The increase in nurse staffing contributed to an increase in many quality metrics. There were an 80% decrease in controllable nurse turnover and a 75% reduction in falls with injury after the lowered nurse-patient ratio. These 2 metrics established a return on investment for the staffing increase. In addition, the staffing satisfaction question on the Press Ganey employee engagement survey increased from 2.44 in 2013 to 3.72 in 2015 in response to the advocacy of the bedside nurses.

  10. Intermediate product selection and blending in the food processing industry

    NARCIS (Netherlands)

    Kilic, Onur A.; Akkerman, Renzo; van Donk, Dirk Pieter; Grunow, Martin

    2013-01-01

    This study addresses a capacitated intermediate product selection and blending problem typical for two-stage production systems in the food processing industry. The problem involves the selection of a set of intermediates and end-product recipes characterising how those selected intermediates are

  11. Future possibilities with intermediate-energy neutron beams

    International Nuclear Information System (INIS)

    Brady, F.P.

    1987-01-01

    Future possibilities for using neutrons of intermediate energies (50 - 200 MeV) as a probe of the nucleus are discussed. Some of the recent thinking concerning a systematic approach for studying elastic and inelastic scattering of electrons and hadrons and the important role of medium- and intermediate-energy neutrons in such a programme is reviewed. The advantages of neutrons in this energy range over neutrons with lower energies and over intermediate-energy pions for determining nuclear-transition and ground state densities, and for distinguishing proton from neutron density (isovector sensitivity), are noted. The important role of (n,p) charge exchange reactions in nuclear excitation studies is also reviewed. Experimental methods for utilizing neutrons as probes in elastic, inelastic, and charge exchange studies at these energies are discussed

  12. The Intermediate Neutrino Program

    Energy Technology Data Exchange (ETDEWEB)

    Adams, C.; et al.

    2015-03-23

    The US neutrino community gathered at the Workshop on the Intermediate Neutrino Program (WINP) at Brookhaven National Laboratory February 4-6, 2015 to explore opportunities in neutrino physics over the next five to ten years. Scientists from particle, astroparticle and nuclear physics participated in the workshop. The workshop examined promising opportunities for neutrino physics in the intermediate term, including possible new small to mid-scale experiments, US contributions to large experiments, upgrades to existing experiments, R&D plans and theory. The workshop was organized into two sets of parallel working group sessions, divided by physics topics and technology. Physics working groups covered topics on Sterile Neutrinos, Neutrino Mixing, Neutrino Interactions, Neutrino Properties and Astrophysical Neutrinos. Technology sessions were organized into Theory, Short-Baseline Accelerator Neutrinos, Reactor Neutrinos, Detector R&D and Source, Cyclotron and Meson Decay at Rest sessions.This report summarizes discussion and conclusions from the workshop.

  13. The Intermediate Neutrino Program

    Energy Technology Data Exchange (ETDEWEB)

    Adams, C. [Yale Univ., New Haven, CT (United States); Alonso, J. R. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Ankowski, A. M. [Virginia Polytechnic Inst. and State Univ. (Virginia Tech), Blacksburg, VA (United States); Asaadi, J. A. [Syracuse Univ., NY (United States); Ashenfelter, J. [Yale Univ., New Haven, CT (United States); Axani, S. N. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Babu, K [Oklahoma State Univ., Stillwater, OK (United States); Backhouse, C. [California Inst. of Technology (CalTech), Pasadena, CA (United States); Band, H. R. [Yale Univ., New Haven, CT (United States); Barbeau, P. S. [Duke Univ., Durham, NC (United States); Barros, N. [Univ. of Pennsylvania, Philadelphia, PA (United States); Bernstein, A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Betancourt, M. [Illinois Inst. of Technology, Chicago, IL (United States); Bishai, M. [Brookhaven National Lab. (BNL), Upton, NY (United States); Blucher, E. [Univ. of Chicago, IL (United States); Bouffard, J. [State Univ. of New York (SUNY), Albany, NY (United States); Bowden, N. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Brice, S. [Illinois Inst. of Technology, Chicago, IL (United States); Bryan, C. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Camilleri, L. [Columbia Univ., New York, NY (United States); Cao, J. [Inst. of High Energy Physics, Beijing (China); Carlson, J. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Carr, R. E. [Columbia Univ., New York, NY (United States); Chatterjee, A. [Univ. of Texas, Arlington, TX (United States); Chen, M. [Univ. of California, Irvine, CA (United States); Chen, S. [Tsinghua Univ., Beijing (China); Chiu, M. [Brookhaven National Lab. (BNL), Upton, NY (United States); Church, E. D. [Illinois Inst. of Technology, Chicago, IL (United States); Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Collar, J. I. [Univ. of Chicago, IL (United States); Collin, G. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Conrad, J. M. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Convery, M. R. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Cooper, R. L. [Indiana Univ., Bloomington, IN (United States); Cowen, D. [Pennsylvania State Univ., University Park, PA (United States); Davoudiasl, H. [Brookhaven National Lab. (BNL), Upton, NY (United States); Gouvea, A. D. [Northwestern Univ., Evanston, IL (United States); Dean, D. J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Deichert, G. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Descamps, F. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); DeYoung, T. [Michigan State Univ., East Lansing, MI (United States); Diwan, M. V. [Brookhaven National Lab. (BNL), Upton, NY (United States); Djurcic, Z. [Argonne National Lab. (ANL), Argonne, IL (United States); Dolinski, M. J. [Drexel Univ., Philadelphia, PA (United States); Dolph, J. [Brookhaven National Lab. (BNL), Upton, NY (United States); Donnelly, B. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Dwyer, D. A. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Dytman, S. [Univ. of Pittsburgh, PA (United States); Efremenko, Y. [Univ. of Tennessee, Knoxville, TN (United States); Everett, L. L. [Univ. of Wisconsin, Madison, WI (United States); Fava, A. [University of Padua, Padova (Italy); Figueroa-Feliciano, E. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Fleming, B. [Yale Univ., New Haven, CT (United States); Friedland, A. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Fujikawa, B. K. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Gaisser, T. K. [Univ. of Delaware, Newark, DE (United States); Galeazzi, M. [Univ. of Miami, FL (United States); Galehouse, DC [Univ. of Akron, OH (United States); Galindo-Uribarri, A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Garvey, G. T. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Gautam, S. [Tribhuvan Univ., Kirtipur (Nepal); Gilje, K. E. [Illinois Inst. of Technology, Chicago, IL (United States); Gonzalez-Garcia, M. [Stony Brook Univ., NY (United States); Goodman, M. C. [Argonne National Lab. (ANL), Argonne, IL (United States); Gordon, H. [Brookhaven National Lab. (BNL), Upton, NY (United States); Gramellini, E. [Yale Univ., New Haven, CT (United States); Green, M. P. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Guglielmi, A. [University of Padua, Padova (Italy); Hackenburg, R. W. [Brookhaven National Lab. (BNL), Upton, NY (United States); Hackenburg, A. [Yale Univ., New Haven, CT (United States); Halzen, F. [Univ. of Wisconsin, Madison, WI (United States); Han, K. [Yale Univ., New Haven, CT (United States); Hans, S. [Brookhaven National Lab. (BNL), Upton, NY (United States); Harris, D. [Illinois Inst. of Technology, Chicago, IL (United States); Heeger, K. M. [Yale Univ., New Haven, CT (United States); Herman, M. [Brookhaven National Lab. (BNL), Upton, NY (United States); Hill, R. [Univ. of Chicago, IL (United States); Holin, A. [Univ. College London, Bloomsbury (United Kingdom); Huber, P. [Virginia Polytechnic Inst. and State Univ. (Virginia Tech), Blacksburg, VA (United States); Jaffe, D. E. [Brookhaven National Lab. (BNL), Upton, NY (United States); Johnson, R. A. [Univ. of Cincinnati, OH (United States); Joshi, J. [Brookhaven National Lab. (BNL), Upton, NY (United States); Karagiorgi, G. [Univ. of Manchester (United Kingdom); Kaufman, L. J. [Indiana Univ., Bloomington, IN (United States); Kayser, B. [Illinois Inst. of Technology, Chicago, IL (United States); Kettell, S. H. [Brookhaven National Lab. (BNL), Upton, NY (United States); Kirby, B. J. [Brookhaven National Lab. (BNL), Upton, NY (United States); Klein, J. R. [Univ. of Texas, Arlington, TX (United States); Kolomensky, Y. G. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Univ. of California, Berkeley, CA (United States); Kriske, R. M. [Univ. of Minnesota, Minneapolis, MN (United States); Lane, C. E. [Drexel Univ., Philadelphia, PA (United States); Langford, T. J. [Yale Univ., New Haven, CT (United States); Lankford, A. [Univ. of California, Irvine, CA (United States); Lau, K. [Univ. of Houston, TX (United States); Learned, J. G. [Univ. of Hawaii, Honolulu, HI (United States); Ling, J. [Univ. of Illinois, Urbana-Champaign, IL (United States); Link, J. M. [Virginia Polytechnic Inst. and State Univ. (Virginia Tech), Blacksburg, VA (United States); Lissauer, D. [Brookhaven National Lab. (BNL), Upton, NY (United States); Littenberg, L. [Brookhaven National Lab. (BNL), Upton, NY (United States); Littlejohn, B. R. [Illinois Inst. of Technology, Chicago, IL (United States); Lockwitz, S. [Illinois Inst. of Technology, Chicago, IL (United States); Lokajicek, M. [Inst. of Physics of the Academy of Sciences of Czech Republic, Prague (Czech Republic); Louis, W. C. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Luk, K. [Univ. of California, Berkeley, CA (United States); Lykken, J. [Illinois Inst. of Technology, Chicago, IL (United States); Marciano, W. J. [Brookhaven National Lab. (BNL), Upton, NY (United States); Maricic, J. [Univ. of Hawaii, Honolulu, HI (United States); Markoff, D. M. [North Carolina Central Univ., Durham, NC (United States); Caicedo, D. A. M. [Illinois Inst. of Technology, Chicago, IL (United States); Mauger, C. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Mavrokoridis, K. [Univ. of Liverpool (United Kingdom); McCluskey, E. [Illinois Inst. of Technology, Chicago, IL (United States); McKeen, D. [Univ. of Washington, Seattle, WA (United States); McKeown, R. [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Mills, G. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Mocioiu, I. [Pennsylvania State Univ., University Park, PA (United States); Monreal, B. [Univ. of California, Santa Barbara, CA (United States); Mooney, M. R. [Brookhaven National Lab. (BNL), Upton, NY (United States); Morfin, J. G. [Illinois Inst. of Technology, Chicago, IL (United States); Mumm, P. [National Inst. of Standards and Technology (NIST), Boulder, CO (United States); Napolitano, J. [Temple Univ., Philadelphia, PA (United States); Neilson, R. [Drexel Univ., Philadelphia, PA (United States); Nelson, J. K. [College of William and Mary, Williamsburg, VA (United States); Nessi, M. [European Organization for Nuclear Research (CERN), Geneva (Switzerland); Norcini, D. [Yale Univ., New Haven, CT (United States); Nova, F. [Univ. of Texas, Austin, TX (United States); Nygren, D. R. [Univ. of Texas, Arlington, TX (United States); Gann, GDO [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Univ. of California, Berkeley, CA (United States); Palamara, O. [Illinois Inst. of Technology, Chicago, IL (United States); Parsa, Z. [Brookhaven National Lab. (BNL), Upton, NY (United States); Patterson, R. [California Inst. of Technology (CalTech), Pasadena, CA (United States); Paul, P. [Stony Brook Univ., NY (United States); Pocar, A. [Univ. of Massachusetts, Amherst, MA (United States); Qian, X. [Brookhaven National Lab. (BNL), Upton, NY (United States); Raaf, J. L. [Illinois Inst. of Technology, Chicago, IL (United States); Rameika, R. [Illinois Inst. of Technology, Chicago, IL (United States); Ranucci, G. [National Inst. of Nuclear Physics, Milano (Italy); Ray, H. [Univ. of Florida, Gainesville, FL (United States); Reyna, D. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Rich, G. C. [Triangle Universities Nuclear Lab., Durham, NC (United States); Rodrigues, P. [Univ. of Rochester, NY (United States); Romero, E. R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Univ. of Tennessee, Knoxville, TN (United States); Rosero, R. [Brookhaven National Lab. (BNL), Upton, NY (United States); Rountree, S. D. [Virginia Polytechnic Inst. and State Univ. (Virginia Tech), Blacksburg, VA (United States); Rybolt, B. [Univ. of Tennessee, Knoxville, TN (United States); Sanchez, M. C. [Iowa State Univ., Ames, IA (United States); Santucci, G. [Stony Brook Univ., NY (United States); Schmitz, D. [Univ. of Chicago, IL (United States); Scholberg, K. [Duke Univ., Durham, NC (United States); Seckel, D. [Univ. of Delaware, Newark, DE (United States); Shaevitz, M. [Columbia Univ., New York, NY (United States); Shrock, R. [Stony Brook Univ., NY (United States); Smy, M. B. [Univ. of California, Irvine, CA (United States); Soderberg, M. [Syracuse Univ., NY (United States); Sonzogni, A. [Brookhaven National Lab. (BNL), Upton, NY (United States); Sousa, A. B. [Univ. of Cincinnati, OH (United States); Spitz, J. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); John, J. M. S. [Univ. of Cincinnati, OH (United States); Stewart, J. [Brookhaven National Lab. (BNL), Upton, NY (United States); Strait, J. B. [Illinois Inst. of Technology, Chicago, IL (United States); Sullivan, G. [Univ. of Maryland, College Park, MD (United States); Svoboda, R. [Univ. of California, Davis, CA (United States); Szelc, A. M. [Yale Univ., New Haven, CT (United States); Tayloe, R. [Indiana Univ., Bloomington, IN (United States); Thomson, M. A. [Univ. of Cambridge (United Kingdom); Toups, M. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Vacheret, A. [Univ. of Oxford (United Kingdom); Vagins, M. [Univ. of California, Irvine, CA (United States); Water, R. G. V. D. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Vogelaar, R. B. [Virginia Polytechnic Inst. and State Univ. (Virginia Tech), Blacksburg, VA (United States); Weber, M. [Bern (Switzerland); Weng, W. [Brookhaven National Lab. (BNL), Upton, NY (United States); Wetstein, M. [Univ. of Chicago, IL (United States); White, C. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); White, B. R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Whitehead, L. [Univ. of Houston, TX (United States); Whittington, D. W. [Indiana Univ., Bloomington, IN (United States); Wilking, M. J. [Stony Brook Univ., NY (United States); Wilson, R. J. [Colorado State Univ., Fort Collins, CO (United States); Wilson, P. [Illinois Inst. of Technology, Chicago, IL (United States); Winklehner, D. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Winn, D. R. [Fairfield Univ., CT (United States); Worcester, E. [Brookhaven National Lab. (BNL), Upton, NY (United States); Yang, L. [Univ. of Illinois, Urbana-Champaign, IL (United States); Yeh, M [Brookhaven National Lab. (BNL), Upton, NY (United States); Yokley, Z. W. [Virginia Polytechnic Inst. and State Univ. (Virginia Tech), Blacksburg, VA (United States); Yoo, J. [Illinois Inst. of Technology, Chicago, IL (United States); Yu, B. [Brookhaven National Lab. (BNL), Upton, NY (United States); Yu, J. [Univ. of Texas, Arlington, TX (United States); Zhang, C. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2017-04-03

    The US neutrino community gathered at the Workshop on the Intermediate Neutrino Program (WINP) at Brookhaven National Laboratory February 4-6, 2015 to explore opportunities in neutrino physics over the next five to ten years. Scientists from particle, astroparticle and nuclear physics participated in the workshop. The workshop examined promising opportunities for neutrino physics in the intermediate term, including possible new small to mid-scale experiments, US contributions to large experiments, upgrades to existing experiments, R&D plans and theory. The workshop was organized into two sets of parallel working group sessions, divided by physics topics and technology. Physics working groups covered topics on Sterile Neutrinos, Neutrino Mixing, Neutrino Interactions, Neutrino Properties and Astrophysical Neutrinos. Technology sessions were organized into Theory, Short-Baseline Accelerator Neutrinos, Reactor Neutrinos, Detector R&D and Source, Cyclotron and Meson Decay at Rest sessions.This report summarizes discussion and conclusions from the workshop.

  14. Comments on intermediate-scale models

    International Nuclear Information System (INIS)

    Ellis, J.; Enqvist, K.; Nanopoulos, D.V.; Olive, K.

    1987-01-01

    Some superstring-inspired models employ intermediate scales m I of gauge symmetry breaking. Such scales should exceed 10 16 GeV in order to avoid prima facie problems with baryon decay through heavy particles and non-perturbative behaviour of the gauge couplings above m I . However, the intermediate-scale phase transition does not occur until the temperature of the Universe falls below O(m W ), after which an enormous excess of entropy is generated. Moreover, gauge symmetry breaking by renormalization group-improved radiative corrections is inapplicable because the symmetry-breaking field has not renormalizable interactions at scales below m I . We also comment on the danger of baryon and lepton number violation in the effective low-energy theory. (orig.)

  15. Review of recent experiments in intermediate energy nuclear physics

    Energy Technology Data Exchange (ETDEWEB)

    Barnes, P D [Carnegie-Mellon Univ., Pittsburgh, PA (USA)

    1978-01-01

    The data generated at intermediate-energy accelerator facilities has expanded rapidly over the past few years. A number of recent experiments chosen for their impact on nuclear structure questions are reviewed. Proton scattering together with pionic and muonic atom X-ray measurements are shown to be giving very precise determinations of gross nuclear properties. Pion scattering and reaction data although less precise, are starting to generate a new understanding of wave functions of specific nuclear states. Specific examples where new unpublished data are now available are emphasized. In addition, other medium-energy experiments that are starting to contribute to nuclear structure physics are summarized.

  16. Surface Intermediate Zone of Submerged Turbulent Buoyant Jet in Current

    DEFF Research Database (Denmark)

    Chen, H. B.; Larsen, Torben

    1995-01-01

    This paper deals with the intermediate zone between the jet and plume stages of a submerged buoyant discharge from sea outfall in current. The stability criteria, plume width and height after the intermediate zone and the dilution within the intermediate region have been studied theoretically and...

  17. Kinetics of a Criegee intermediate that would survive high humidity and may oxidize atmospheric SO2.

    Science.gov (United States)

    Huang, Hao-Li; Chao, Wen; Lin, Jim Jr-Min

    2015-09-01

    Criegee intermediates are thought to play a role in atmospheric chemistry, in particular, the oxidation of SO2, which produces SO3 and subsequently H2SO4, an important constituent of aerosols and acid rain. However, the impact of such oxidation reactions is affected by the reactions of Criegee intermediates with water vapor, because of high water concentrations in the troposphere. In this work, the kinetics of the reactions of dimethyl substituted Criegee intermediate (CH3)2COO with water vapor and with SO2 were directly measured via UV absorption of (CH3)2COO under near-atmospheric conditions. The results indicate that (i) the water reaction with (CH3)2COO is not fast enough (kH2O SO2 at a near-gas-kinetic-limit rate (kSO2 = 1.3 × 10(-10) cm(3) s(-1)). These observations imply a significant fraction of atmospheric (CH3)2COO may survive under humid conditions and react with SO2, very different from the case of the simplest Criegee intermediate CH2OO, in which the reaction with water dimer predominates in the CH2OO decay under typical tropospheric conditions. In addition, a significant pressure dependence was observed for the reaction of (CH3)2COO with SO2, suggesting the use of low pressure rate may underestimate the impact of this reaction. This work demonstrates that the reactivity of a Criegee intermediate toward water vapor strongly depends on its structure, which will influence the main decay pathways and steady-state concentrations for various Criegee intermediates in the atmosphere.

  18. Computational uncertainties in silicon dioxide/plutonium intermediate neutron spectrum systems

    International Nuclear Information System (INIS)

    Jaegers, P.J.

    1997-01-01

    In the past several years, several proposals have been made for the long-term stabilization and storage of surplus fissile materials. Many of these proposed scenarios involve systems that have an intermediate neutron energy spectrum. Such intermediate-energy systems are dominated by scattering and fission events induced by neutrons ranging in energy from 1 eV to 100keV. To ensure adequate safety margins and cost effectiveness, it is necessary to have benchmark data for these intermediate-energy spectrum systems; however, a review of the nuclear criticality benchmarks indicates that no formal benchmarks are available. Nuclear data uncertainties have been reported for some types of intermediate-energy spectrum systems. Using a variety of Monte Carlo computer codes and cross-section sets, reported significant variations in the calculated k ∞ of intermediate-energy spectrum metal/ 235 U systems. We discuss the characteristics of intermediate neutron spectrum systems and some of the computational differences that can occur in calculating the k eff of these systems

  19. On the stability of rotational discontinuities and intermediate shocks

    International Nuclear Information System (INIS)

    Lee, L.C.; Huang, L.; Chao, J.K.

    1989-01-01

    The stability of rotational discontinuities and intermediate shocks is studied based on a hybrid simulation code. The simulation results show that rotational discontinuities are stable and intermediate shocks are not stationary. Intermediate shocks tend to evolve to rotational discontinuities and waves. The authors employ several different initial profiles for the magnetic field in the transition region and find that the final structure of the discontinuities or shocks is not sensitive to the initial magnetic field profile. The present results are different from those obtained from the resistive MHD simulations. Furthermore, their study indicates that the kinetic effect of particles plays an important role in the structure and stability of rotational discontinuities and intermediate shocks

  20. Treatment of low- and intermediate-level liquid radioactive wastes

    International Nuclear Information System (INIS)

    1984-01-01

    This report aims at giving the reader details of the experience gained in the treatment of both low- and intermediate-level radioactive liquid wastes. The treatment comprises those operations to remove radioactivity from the wastes and those that change only its chemical composition, so as to permit its discharge. Considerable experience has been accumulated in the satisfactory treatment of such wastes. Although there are no universally accepted definitions for low- and intermediate-level liquid radioactive wastes, the IAEA classification (see section 3.2) is used in this report. The two categories differ from one another in the fact that for low-level liquids the actual radiation does not require shielding during normal handling of the wastes. Liquid wastes which are not considered in this report are those from mining and milling operations and the high-level liquid wastes resulting from fuel reprocessing. These are referred to in separate IAEA reports. Likewise, wastes from decommissioning operations are not within the scope of this report. Apart from the description of existing methods and facilities, this report is intended to provide advice to the reader for the selection of appropriate solutions to waste management problems. In addition, new and promising techniques which are either being investigated or being considered for the future are discussed

  1. MNE Entrepreneurial Capabilities at Intermediate Levels

    DEFF Research Database (Denmark)

    Hoenen, Anne K.; Nell, Phillip Christopher; Ambos, Björn

    2014-01-01

    at intermediate geographical levels differ from local subsidiaries and global corporate headquarters, and why those differences are important. We illustrate our arguments using data on European regional headquarters (RHQs). We find that RHQs' entrepreneurial capabilities depend on their external embeddedness...... and on the heterogeneous information that is generated through dissimilar markets within the region. Our study opens up for an interesting discussion of the independence of these mechanisms. In sum, we contribute to the understanding of the entrepreneurial role of intermediate units in general and RHQs in particular....

  2. Development of National Technology Audit Policy

    OpenAIRE

    Subiyanto Subiyanto

    2017-01-01

    The Laws have mandated implementation of technology audit, nevertheless such implementation needs an additional policy that is more technical. The concept of national audit technology policy shall make technology audit as a tool to ensure the benefit of technology application for society and technology advance for nation independency. This article discusses on technology audit policy concept especially infrastructure requirement, with emphasis on regulation, implementation tools, and related ...

  3. Financial Intermediation and Economic Growth of Jordan 1964-1988

    OpenAIRE

    Magableh, Ali H.

    1995-01-01

    Until recently, the economics and financial literature placed little attention on the role that financial intermediation can play in accelerating the rate of economic development in less Developed Countries (LDCs). This has been changed now, however, where some instrumental role has been emphasised for financial intermediation in the process of economic development and growth. It is argued that an expansion of the financial system, size and intermediation in LDCs tends to increase the level o...

  4. Perspective: Spectroscopy and kinetics of small gaseous Criegee intermediates

    International Nuclear Information System (INIS)

    Lee, Yuan-Pern

    2015-01-01

    The Criegee intermediates, carbonyl oxides proposed by Criegee in 1949 as key intermediates in the ozonolysis of alkenes, play important roles in many aspects of atmospheric chemistry. Because direct detection of these gaseous intermediates was unavailable until recently, previous understanding of their reactions, derived from indirect experimental evidence, had great uncertainties. Recent laboratory detection of the simplest Criegee intermediate CH 2 OO and some larger members, produced from ultraviolet irradiation of corresponding diiodoalkanes in O 2 , with various methods such as photoionization, ultraviolet absorption, infrared absorption, and microwave spectroscopy opens a new door to improved understanding of the roles of these Criegee intermediates. Their structures and spectral parameters have been characterized; their significant zwitterionic nature is hence confirmed. CH 2 OO, along with other products, has also been detected directly with microwave spectroscopy in gaseous ozonolysis reactions of ethene. The detailed kinetics of the source reaction, CH 2 I + O 2 , which is critical to laboratory studies of CH 2 OO, are now understood satisfactorily. The kinetic investigations using direct detection identified some important atmospheric reactions, including reactions with NO 2 , SO 2 , water dimer, carboxylic acids, and carbonyl compounds. Efforts toward the characterization of larger Criegee intermediates and the investigation of related reactions are in progress. Some reactions of CH 3 CHOO are found to depend on conformation. This perspective examines progress toward the direct spectral characterization of Criegee intermediates and investigations of the associated reaction kinetics, and indicates some unresolved problems and prospective challenges for this exciting field of research

  5. The packaging and transport of low and intermediate level radioactive wastes

    International Nuclear Information System (INIS)

    Grover, J.R.; Price, M.S.T.

    1985-01-01

    Up to the present time, the majority of the radioactive waste which has been transported in the United Kingdom has been low level waste for disposal in the trenches of the shallow burial site operated by British Nuclear Fuels plc at Drigg and also the packaged waste destined for sea disposal in the annual operation. However, the main bulk of the low and intermediate level wastes which have been generated over the last quarter century remain in store at the various nuclear sites where it originated. Before significant packaging and transport of intermediate level wastes takes place it is desirable to examine the sources and types of wastes, the immobilisation and packaging processes and plants, the transport, and the problems of handling of packages at future land repositories. Optimisation of the packaging and transport must take account of both the upstream and downstream con=straints as well as the implications of complying with both the IAEA Transport Regulations and radiological protection guidelines. Packages for sea disposal must in addition comply with the requirements of the London Dumping Convention and the NEA guidelines. (author)

  6. Surface intermediates on metal electrodes at high temperatures

    DEFF Research Database (Denmark)

    Zachau-Christiansen, Birgit; Jacobsen, Torben; Bay, Lasse

    1998-01-01

    The mechanisms widely conceived for the O(2)-reduction or H(2)-oxidation reactions in SOFC's involve intermediate O/H species adsorbed on the electrode surface. The presence of these intermediates is investigated by linear sweep voltammetry. In air at moderate temperatures (500 degrees C) Pt...

  7. Modern Lithuanian foreign policy: the adjustment of traditional policy

    Directory of Open Access Journals (Sweden)

    Batorshina Irina

    2011-12-01

    Full Text Available The authors consider the core areas of Lithuanian foreign policy. Special attention is paid to the adjustment of the major foreign policy vector, which concentrated earlier on the cooperation with the United States of America and strategic partnership with the Republic of Poland. The article analyses the attempts of Lithuanian president Dalia Grybauskaitė to formulate the so-called «new foreign policy» based on the multivector approach to the intergovernmental cooperation. This research is timely because of an increasing influence of small states on foreign policy decision-making within the European Union. It emphasizes the need to analyse foreign policy priorities of the Baltic States and Central and Eastern European countries and to identify the dominant trends in the international policy in the region in order to forecast further development at European and global levels. This objective is achieved with the help of an integrated approach with elements of interdisciplinary research. Special attention is paid to the comparative-historical approach, which facilitates the analysis of the relations between the Republic of Lithuania and the neighbouring states and its principal partners. Alongside traditional methods of historical research, this work employs such methods as participant observation, content and event analysis, and simultaneous and comparative analysis. The research and practical significance of this work is explained by its emphasis on the need to apply an additional theoretical framework to studies into the foreign policy initiatives of the Republic of Lithuania in the international arena. While earlier they were determined by the value (democratic approach, which was a reflection of American realism, today an increasingly important factor is the personality of the president, who does not always positively influence the changing policy of the country. The results of the research contribute substantially to the understanding of

  8. Partially filled intermediate band of Cr-doped GaN films

    International Nuclear Information System (INIS)

    Sonoda, S.

    2012-01-01

    We investigated the band structure of sputtered Cr-doped GaN (GaCrN) films using optical absorption, photoelectron yield spectroscopy, and charge transport measurements. It was found that an additional energy band is formed in the intrinsic band gap of GaN upon Cr doping, and that charge carriers in the material move in the inserted band. Prototype solar cells showed enhanced short circuit current and open circuit voltage in the n-GaN/GaCrN/p-GaN structure compared to the GaCrN/p-GaN structure, which validates the proposed concept of an intermediate-band solar cell.

  9. Intermediate-Mass Black Holes

    Science.gov (United States)

    Miller, M. Coleman; Colbert, E. J. M.

    2004-01-01

    The mathematical simplicity of black holes, combined with their links to some of the most energetic events in the universe, means that black holes are key objects for fundamental physics and astrophysics. Until recently, it was generally believed that black holes in nature appear in two broad mass ranges: stellar-mass (M~3 20 M⊙), which are produced by the core collapse of massive stars, and supermassive (M~106 1010 M⊙), which are found in the centers of galaxies and are produced by a still uncertain combination of processes. In the last few years, however, evidence has accumulated for an intermediate-mass class of black holes, with M~102 104 M⊙. If such objects exist they have important implications for the dynamics of stellar clusters, the formation of supermassive black holes, and the production and detection of gravitational waves. We review the evidence for intermediate-mass black holes and discuss future observational and theoretical work that will help clarify numerous outstanding questions about these objects.

  10. Intermediate Levels of Visual Processing

    National Research Council Canada - National Science Library

    Nakayama, Ken

    1998-01-01

    ...) surface representation, here we have shown that there is an intermediate level of visual processing, between the analysis of the image and higher order representations related to specific objects; (2...

  11. Intermediate energy proton and light-ion scattering

    International Nuclear Information System (INIS)

    Moss, J.M.

    1981-01-01

    A review is presented of recent (1979-81) developments in the field of intermediate-energy proton and light-ion scattering from nuclei. New theoretical and calculational techniques of particular interest to experimentalists are discussed. Emphasis is placed on topics in nuclear structure physics - giant resonances, pion-condensation precursor phenomena, and polarization transfer (spin-flip) experiments - where intermediate energy proton and light-ion scattering has made new and unique contributions

  12. Linear-XOR and Additive Checksums Don't Protect Damgard-Merkle Hashes

    DEFF Research Database (Denmark)

    Gauravaram, Praveen; Kelsey, John

    2008-01-01

    We consider the security of Damg\\aa{}rd-Merkle variants which compute linear-XOR or additive checksums over message blocks, intermediate hash values, or both, and process these checksums in computing the final hash value. We show that these Damg\\aa{}rd-Merkle variants gain almost no security...

  13. Comments on intermediate-scale models

    Energy Technology Data Exchange (ETDEWEB)

    Ellis, J.; Enqvist, K.; Nanopoulos, D.V.; Olive, K.

    1987-04-23

    Some superstring-inspired models employ intermediate scales m/sub I/ of gauge symmetry breaking. Such scales should exceed 10/sup 16/ GeV in order to avoid prima facie problems with baryon decay through heavy particles and non-perturbative behaviour of the gauge couplings above m/sub I/. However, the intermediate-scale phase transition does not occur until the temperature of the Universe falls below O(m/sub W/), after which an enormous excess of entropy is generated. Moreover, gauge symmetry breaking by renormalization group-improved radiative corrections is inapplicable because the symmetry-breaking field has not renormalizable interactions at scales below m/sub I/. We also comment on the danger of baryon and lepton number violation in the effective low-energy theory.

  14. Predicting the functions and specificity of triterpenoid synthases: a mechanism-based multi-intermediate docking approach.

    Directory of Open Access Journals (Sweden)

    Bo-Xue Tian

    2014-10-01

    Full Text Available Terpenoid synthases construct the carbon skeletons of tens of thousands of natural products. To predict functions and specificity of triterpenoid synthases, a mechanism-based, multi-intermediate docking approach is proposed. In addition to enzyme function prediction, other potential applications of the current approach, such as enzyme mechanistic studies and enzyme redesign by mutagenesis, are discussed.

  15. Proceedings of the Workshop on Program Options in Intermediate-Energy Physics. Keynote address: New directions in intermediate-energy nuclear physics

    International Nuclear Information System (INIS)

    Brown, G.E.

    1980-05-01

    This report presents the keynote address given by G.E. Brown at a LASL colloquium on August 21, 1979, for the Workshop on Program Options in Intermediate-Energy Physics. Professor Brown reviewed major topics of interest in intermediate-energy nuclear physics and suggested experimental approaches that might be most productive in the near future. 22 figures

  16. Stability and anti-glycation properties of intermediate moisture apple products fortified with green tea.

    Science.gov (United States)

    Lavelli, Vera; Corey, Mark; Kerr, William; Vantaggi, Claudia

    2011-07-15

    Intermediate moisture products made from blanched apple flesh and green tea extract (about 6mg of monomeric flavan 3-ols added per g of dry apple) or blanched apple flesh (control) were produced, and their quality attributes were investigated over storage for two months at water activity (a(w)) levels of 0.55 and 0.75, at 30°C. Products were evaluated for colour (L(∗), a(∗), and b(∗) Hunter's parameters), phytochemical contents (flavan 3-ols, chlorogenic acid, dihydrochalcones, ascorbic acid and total polyphenols), ferric reducing antioxidant potential, 2,2-diphenyl-1-(2,4,6-trinitrophenyl)hydrazyl radical-scavenging activity and ability to inhibit formation of fructose-induced advanced glycation end-products. During storage of the fortified and unfortified intermediate moisture apples, water availability was sufficient to support various chemical reactions involving phytochemicals, which degraded at different rates: ascorbic acid>flavan 3-ols>dihydrochalcones and chlorogenic acid. Colour variations occurred at slightly slower rates after green tea addition. In the intermediate moisture apple, antioxidant and anti-glycoxidative properties decreased at similar rates (half-life was about 80d at a(w) of 0.75, 30°C). In the green tea-fortified intermediate moisture apple, the antioxidant activity decreased at a slow rate (half-life was 165d at a(w) of 0.75, 30°C) and the anti-glycoxidative properties did not change, indicating that flavan 3-ol degradation involved the formation of derivatives that retained the properties of their parent compounds. Since these properties are linked to oxidative- and advanced glycation end-product-related diseases, these results suggest that green tea fortification of intermediate moisture apple products could be a valuable means of product innovation, to address consumers' nutritional needs. Copyright © 2011 Elsevier Ltd. All rights reserved.

  17. Projecting non-diffracting waves with intermediate-plane holography.

    Science.gov (United States)

    Mondal, Argha; Yevick, Aaron; Blackburn, Lauren C; Kanellakopoulos, Nikitas; Grier, David G

    2018-02-19

    We introduce intermediate-plane holography, which substantially improves the ability of holographic trapping systems to project propagation-invariant modes of light using phase-only diffractive optical elements. Translating the mode-forming hologram to an intermediate plane in the optical train can reduce the need to encode amplitude variations in the field, and therefore complements well-established techniques for encoding complex-valued transfer functions into phase-only holograms. Compared to standard holographic trapping implementations, intermediate-plane holograms greatly improve diffraction efficiency and mode purity of propagation-invariant modes, and so increase their useful non-diffracting range. We demonstrate this technique through experimental realizations of accelerating modes and long-range tractor beams.

  18. Policies promoting Biofuels in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Holmgren, Kristina [IVL Swedish Environmental Research Inst., Goeteborg (Sweden); Chalmers Univ. of Technology, Div. of Heat and Power Technology., Goeteborg (Sweden)

    2012-07-01

    This report was written as part of a course in Environmental Economics and Policy Instruments at the University of Gothenburg. It aims at summarizing the policy instruments introduced to directly affect the production and use of biofuels in Sweden. Since Sweden is part of the EU also EU policies were included. There are additional policy instruments which affect the production and utilization of biofuels in a more indirect way that are not presented here. The economic analysis in this paper is limited and could be developed from the information presented in order to draw further conclusions on necessary changes in order to reach set targets.

  19. Surface Intermediates on Metal Electrodes at High Temperature

    DEFF Research Database (Denmark)

    Zachau-Christiansen, Birgit; Jacobsen, Torben; Bay, Lasse

    1997-01-01

    The mechanisms widely suggested for the O2-reduc-tion or H2-oxidation SOFC reactions involve inter-mediate O/H species adsorbed on the electrode surface. The presence of these intermediates is investigated by linear sweep voltammetry. In airat moderate temperatures (500øC) Pt in contact with YSZ...

  20. Processing and validation of intermediate energy evaluated data files

    International Nuclear Information System (INIS)

    2000-01-01

    Current accelerator-driven and other intermediate energy technologies require accurate nuclear data to model the performance of the target/blanket assembly, neutron production, activation, heating and damage. In a previous WPEC subgroup, SG13 on intermediate energy nuclear data, various aspects of intermediate energy data, such as nuclear data needs, experiments, model calculations and file formatting issues were investigated and categorized to come to a joint evaluation effort. The successor of SG13, SG14 on the processing and validation of intermediate energy evaluated data files, goes one step further. The nuclear data files that have been created with the aforementioned information need to be processed and validated in order to be applicable in realistic intermediate energy simulations. We emphasize that the work of SG14 excludes the 0-20 MeV data part of the neutron evaluations, which is supposed to be covered elsewhere. This final report contains the following sections: section 2: a survey of the data files above 20 MeV that have been considered for validation in SG14; section 3: a summary of the review of the 150 MeV intermediate energy data files for ENDF/B-VI and, more briefly, the other libraries; section 4: validation of the data library against an integral experiment with MCNPX; section 5: conclusions. (author)

  1. Intercomparison of codes for intermediate energy nuclear data: The first step

    International Nuclear Information System (INIS)

    Blann, M.; Gruppelaar, H.; Nagel, P.; Rodens, J.

    1994-01-01

    Several weak points of the intermediate energy nuclear data calculated in this exercise are described as introduction to some of the areas needing discussion at this meeting. These include nuclear structure effects on precompound spectra, large variations between codes in predicted total reaction cross sections, and in total neutron and proton multiplicities. INC codes don't reflect correct experimental Q values, and may have difficulties at very low angles due to overestimation of the quasi-elastic peak. We raise questions as to additional reaction properties (beyond n and p spectra) which may need benchmarking

  2. Environmental effects of disposal of intermediate-level wastes by shale fracturing

    International Nuclear Information System (INIS)

    Weeren, H.O.

    1978-01-01

    Shale fracturing is a process currently being used at the Oak Ridge National Laboratory for the permanent disposal of locally generated, intermediate-level waste solutions. In this process, the waste is mixed with a solids blend of cement and other additives; the resulting grout is then injected into an impermeable shale formation at a depth of 700 to 1000 ft. A few hours after completion of the injection, the grout sets and the radioactive waste are fixed in the shale formation. An analysis of environmental effects of normal operation and possible accident situations is discussed

  3. An improved intermediate resonance method for heterogeneous media

    International Nuclear Information System (INIS)

    Chiovato, O.; Corno, S.; Pasquantonio, F.Di.

    1977-01-01

    A new formulation is described of the Intermediate Resonance method which incorporates the previous developments suitably modified and improved, together with some new contributions. The 'intermediate' character is directly introduced in the integral operator K, allowing a more rigorous deduction of the equations for evaluating the intermediate parameters related to the nuclides involved in the system. There is no limit to the number of internal (admixed in the fuel) and external moderators. The capability to take into account the interference scattering has been extended to heterogeneous systems. The Doppler broadening is described by means of new accurate rational approximations to the broadened line shape psi. Finally the use of energy mean values suitably defined refines the values of the resonance integrals and resonance absorption cross sections. The Intermediate Resonance method so extended and improved, has been coded in a group of FORTRAN routines, which have been inserted as a calculation option in the fast section of the GGC code for the evaluation of multigroup cross sections. A series of calculations has been carried out, using these routines, and comparisons have been made with Monte Carlo and Nordheim's methods. The results obtained show that the Intermediate Resonance method developed in the present work offers considerable advantages over Nordheim's method: better accuracy in evaluating resonance absorption cross sections, and much smaller computing times. (author)

  4. Long G2 accumulates recombination intermediates and disturbs chromosome segregation at dysfunction telomere in Schizosaccharomyces pombe

    Energy Technology Data Exchange (ETDEWEB)

    Habib, Ahmed G.K.; Masuda, Kenta; Yukawa, Masashi; Tsuchiya, Eiko [Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima 739-8530 (Japan); Ueno, Masaru, E-mail: scmueno@hiroshima-u.ac.jp [Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima 739-8530 (Japan); Research Center for the Mathematics on Chromatin Live Dynamics, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima 739-8530 (Japan)

    2015-08-14

    Protection of telomere (Pot1) is a single-stranded telomere binding protein which is essential for chromosome ends protection. Fission yeast Rqh1 is a member of RecQ helicases family which has essential roles in the maintenance of genomic stability and regulation of homologous recombination. Double mutant between fission yeast pot1Δ and rqh1 helicase dead (rqh1-hd) maintains telomere by homologous recombination. In pot1Δ rqh1-hd double mutant, recombination intermediates accumulate near telomere which disturb chromosome segregation and make cells sensitive to microtubule inhibitors thiabendazole (TBZ). Deletion of chk1{sup +} or mutation of its kinase domain shortens the G2 of pot1Δ rqh1-hd double mutant and suppresses both the accumulation of recombination intermediates and the TBZ sensitivity of that double mutant. In this study, we asked whether the long G2 is the reason for the TBZ sensitivity of pot1Δ rqh1-hd double mutant. We found that shortening the G2 of pot1Δ rqh1-hd double mutant by additional mutations of wee1 and mik1 or gain of function mutation of Cdc2 suppresses both the accumulation of recombination intermediates and the TBZ sensitivity of pot1Δ rqh1-hd double mutant. Our results suggest that long G2 of pot1Δ rqh1-hd double mutant may allow time for the accumulation of recombination intermediates which disturb chromosome segregation and make cells sensitive to TBZ. - Ηighlights: • We show link between long G2 and accumulation of toxic recombination intermediates. • Accumulation of recombination intermediates at telomere results in TBZ sensitivity. • Activation of DNA damage checkpoint worsens cells' viability in presence of TBZ.

  5. Policy-Making Theory as an Analytical Framework in Policy Analysis: Implications for Research Design and Professional Advocacy.

    Science.gov (United States)

    Sheldon, Michael R

    2016-01-01

    Policy studies are a recent addition to the American Physical Therapy Association's Research Agenda and are critical to our understanding of various federal, state, local, and organizational policies on the provision of physical therapist services across the continuum of care. Policy analyses that help to advance the profession's various policy agendas will require relevant theoretical frameworks to be credible. The purpose of this perspective article is to: (1) demonstrate the use of a policy-making theory as an analytical framework in a policy analysis and (2) discuss how sound policy analysis can assist physical therapists in becoming more effective change agents, policy advocates, and partners with other relevant stakeholder groups. An exploratory study of state agency policy responses to address work-related musculoskeletal disorders is provided as a contemporary example to illustrate key points and to demonstrate the importance of selecting a relevant analytical framework based on the context of the policy issue under investigation. © 2016 American Physical Therapy Association.

  6. New food policy

    DEFF Research Database (Denmark)

    Christensen, Tove; Andersen, Lill

    The urbanisation, technical changes, and the industrialisation of the food systems on one hand and increased income and changes in lifestyles on the other hand transform the way food is produced, marketed and consumed - those changes call for changes in the nature of food policy. Concerns over food...... safety have become an important driver of reform of food policy. In particular, the BSE crisis in 1996 had a significant impact on the formulation of a change in food safety policy in the EU. The White Paper on Food Safety was prepared by the EU commision as a response to the BSE scandal as the EU felt...... a need for restablishing public confidence in its food supply, its food science, its laws and its food control. In addition, the White Paper on Food Safety points towards a farm to fork policy in that 'as the food production chain is becoming increasingly complex, the health of consumers can ony...

  7. Mechanism of action of clostridial glycine reductase: Isolation and characterization of a covalent acetyl enzyme intermediate

    International Nuclear Information System (INIS)

    Arkowitz, R.A.; Abeles, R.H.

    1991-01-01

    Clostridial glycine reductase consists of proteins A, B, and C and catalyzes the reaction glycine + P i + 2e - → acetyl phosphate + NH 4 + . Evidence was previously obtained that is consistent with the involvement of an acyl enzyme intermediate in this reaction. The authors now demonstrate that protein C catalyzes exchange of [ 32 P]P i into acetyl phosphate, providing additional support for an acetyl enzyme intermediate on protein C. Furthermore, they have isolated acetyl protein C and shown that it is qualitatively, catalytically competent. Acetyl protein C can be obtained through the forward reaction from protein C and Se-(carboxymethyl)selenocysteine-protein A, which is generated by the reaction of glycine with proteins A and B. Acetyl protein C can also be generated through the reverse reaction by the addition of acetyl phosphate to protein C. Both procedures lead to the same acetyl enzyme. The acetyl enzyme reacts with P i to give acetyl phosphate. When [ 14 C]acetyl protein C is denaturated with TCA and redissolved with urea, radioactivity remained associated with the protein. Treatment with KBH 4 removes all the radioactivity associated with protein C, resulting in the formation of [ 14 C]ethanol. They conclude that a thiol group on protein C is acetylated. Proteins A and C together catalyze the exchange of tritium atoms from [ 3 H]H 2 O into acetyl phosphate. This exchange reaction supports the proposal that an enol of the acetyl enzyme is an intermediate in the reaction sequence

  8. Fiscal and monetary policy interactions in an endogenous growth model with financial intermediaries

    OpenAIRE

    Espinosa, Marco A.; Yip, Chong K.

    1995-01-01

    We review some inflationary and growth claims surrounding fiscal and monetary policy interactions. While financial intermediation has long been acknowledged as a key mechanism in the transmission of these interactions, only recently have economists incorporated the explicit modeling of such intermediaries in their analyses. Here we model financial intermediaries explicitly. We find that the relation between growth and inflation depends crucially on the agents' degree of relative risk aversion...

  9. The management of intermediate level wastes in Sweden

    International Nuclear Information System (INIS)

    Hultgren, Aa.; Thegerstroem, C.

    1980-01-01

    A brief overview of current practices and research in Sweden on the management of intermediate level wastes is given. Intermediate level wastes include spent resins, filters and core components from the six power reactors in operation; radioactive wastes from nuclear fuel development at Studsvik and from non-nuclear applications are a minor contribution. (Auth.)

  10. PRIORITIZING ECONOMIC GROWTH: ENHANCING MACROECONOMIC POLICY CHOICE

    OpenAIRE

    Colin I. BRADFORD, Jr.

    2005-01-01

    This paper spells out a logic for increasing macroeconomic policy space in order to prioritize the goals of growth, employment creation and poverty reduction. First, there is the need to create additional policy instruments so that a greater number of policy goals can be addressed. Frequently, real economy goals get partly crowded out by financial objectives because there are too few instruments for too many goals. Second, the calibrated use of policy tools by degrees of commitment, deploymen...

  11. Monetary Policy Analysis in Serbia

    Directory of Open Access Journals (Sweden)

    Martin Vesna

    2015-09-01

    Full Text Available The paper focuses on analysing monetary policy in Serbia. The National Bank of Serbia chose inflation targeting, which sets price stability as the main objective of monetary policy. To achieve this goal, the central bank uses different monetary policy instruments which analysis can provide us with the understanding of the main directions of their actions but also of the limitations of its application. Only through improvement of both instruments and monetary policy the central bank will create a better foundation for achieving monetary stability. In addition, the implementation of exchange rate policy is entrusted to the National Bank of Serbia, as the main regulator of the financial system. A mere use of managed floating exchange rate, as the chosen exchange rate regime, is an appropriate solution in the current economic circumstances and in accordance with the desired objective of monetary policy.

  12. Preliminary thermal sizing of intermediate heat exchanger for NHDD system

    International Nuclear Information System (INIS)

    Kim, Chan Soo; Hong, Sung Deok; Kim, Yong Wan; Chang, Jongh Wa

    2009-01-01

    Nuclear Hydrogen Development and Demonstration (NHDD) system is a Very High Temperature gascooled Reactor (VHTR) coupled with hydrogen production systems. Intermediate heat exchanger transfers heat from the nuclear reactor to the hydrogen production system. This study presented the sensitivity analysis on a preliminary thermal sizing of the intermediate heat exchanger. Printed Circuit Heat Exchanger (PCHE) was selected for the thermal sizing because the printed circuit heat exchanger has the largest compactness among the heat exchanger types. The analysis was performed to estimate the effect of key parameters including the operating condition of the intermediate system, the geometrical factors of the PCHE, and the working fluid of the intermediate system.

  13. Intermediate mass distribution of the dual resonance pomeron

    International Nuclear Information System (INIS)

    Chiu, C.B.; Matsuda, S.

    1978-01-01

    The intermediate mass distribution of the dual resonance pomeron is determined at the one-loop level and it is shown that the mass distribution obtained is remarkably similar to a suitably defined mass distribution in the dual multiperipheral model. Thus it is suggestive to identify the intermediate states of the dual resonance pomeron with multiperipheral processes. (Auth.)

  14. CONDITIONING OF INTERMEDIATE-LEVEL WASTE AT FORSCHUNGSZENTRUM JUELICH GMBH

    International Nuclear Information System (INIS)

    Krumbach, H.

    2003-01-01

    This contribution to the group of low-level, intermediate, mixed and hazardous waste describes the conditioning of intermediate-level mixed waste (dose rate above 10 mSv/h at the surface) from Research Centre Juelich (FZJ). Conditioning of the waste by supercompaction is performed at Research Centre Karlsruhe (FZK). The waste described is radioactive waste arising from research at Juelich. This waste includes specimens and objects from irradiation experiments in the research reactors Merlin (FRJ-1) and Dido (FRJ-2) at FZJ. In principle, radioactive waste at Forschungszentrum Juelich GmbH is differentiated by the surface dose rate at the waste package. Up to a surface dose rate of 10 mSv/h, the waste is regarded as low-level. The radioactive waste described here has a surface dose rate above 10 mSv/h. Waste up to 10 mSv/h is conditioned at the Juelich site according to different conditioning methods. The intermediate-level waste can only be conditioned by supercompaction in the processing facility for intermediate-level waste from plant operation at Research Centre Karlsruhe. Research Centre Juelich also uses this waste cell to condition its intermediate-level waste from plant operation

  15. Supersymmetry and intermediate symmetry breaking in SO(10) superunification

    International Nuclear Information System (INIS)

    Asatryan, H.M.; Ioannisyan, A.N.

    1985-01-01

    A scheme of simultaneous breakdown of intermediate symmetry SO(10) → SU(3)sub(c) x U(1) x SU(2)sub(L) x SU(2)sub(R) and supersymmetry by means of a single scale parameter is suggested. This intermediate symmetry, which is preferable physically, owing to the broken supersymmetry has a minimum lying lower than SU(4) x SU(2)sub(L) x SU(2)sub(R). The intermediate symmetry is broken by the vacuum expectation value of the Higgs superfields. Owing to the quantum corrections the potential minimum turns out to correspond to breakdown of the intermediate symmetry up to the standard group SU(3)sub(c) x SU(2)sub(L) x U(1)sub(y). The value of the Weinberg angle is less than that in the supersymmetric SU(5) model and agrees with the experiment

  16. DEVELOPING STATE POLICIES SUPPORTIVE OF BIOENERGY DEVELOPMENT

    Energy Technology Data Exchange (ETDEWEB)

    Kathryn Baskin

    2005-04-30

    Working within the context of the Southern States Biobased Alliance (SSBA) and with officials in each state, the Southern States Energy Board (SSEB) is identifying bioenergy-related policies and programs within each state to determine their impact on the development, deployment or use of bioenergy. In addition, SSEB will determine which policies have impacted industry's efforts to develop, deploy or use biobased technologies or products. As a result, SSEB will work with the Southern States Biobased Alliance to determine how policy changes might address any negative impacts or enhance positive impacts. In addition to analysis of domestic policies and programs, this project will include the development of a U.S.-Brazil Biodiesel Pilot Project. The purpose of this effort is to promote and facilitate the commercialization of biodiesel and bioenergy production and demand in Brazil.

  17. DEVELOPING STATE POLICIES SUPPORTIVE OF BIOENERGY DEVELOPMENT

    Energy Technology Data Exchange (ETDEWEB)

    Kathryn Baskin

    2004-10-31

    Working within the context of the Southern States Biobased Alliance (SSBA) and with officials in each state, the Southern States Energy Board (SSEB) is identifying bioenergy-related policies and programs within each state to determine their impact on the development, deployment or use of bioenergy. In addition, SSEB will determine which policies have impacted industry's efforts to develop, deploy or use biobased technologies or products. As a result, SSEB will work with the Southern States Biobased Alliance to determine how policy changes might address any negative impacts or enhance positive impacts. In addition to analysis of domestic policies and programs, this project will include the development of a U.S.-Brazil Biodiesel Pilot Project. The purpose of this effort is to promote and facilitate the commercialization of biodiesel and bioenergy production and demand in Brazil.

  18. Norwegian work on establishing a combined storage and disposal facility for low and intermediate level waste; Vurdering av det planlagte kombinerte lager og deponi for radioaktivt avfall i Himdalen

    Energy Technology Data Exchange (ETDEWEB)

    International Atomic Energy Agency WATRP Review Team

    1995-12-01

    The IAEA has, through its Waste Management Assessment and Technical Review Programme (WATRP), evaluated policies and facilities related to management of radioactive waste in Norway. It is concluded that the Himdalen site, in combination with the chosen engineering concept, can be suitable for the storage and disposal of the relatively small amounts of Norwegian low and intermediate level waste.

  19. Nickel/zinc-catalyzed decarbonylative addition of anhydrides to alkynes: a DFT study.

    Science.gov (United States)

    Meng, Qingxi; Li, Ming

    2013-10-01

    Density functional theory (DFT) was used to investigate the nickel- or nickel(0)/zinc- catalyzed decarbonylative addition of phthalic anhydrides to alkynes. All intermediates and transition states were optimized completely at the B3LYP/6-31+G(d,p) level. Calculated results indicated that the decarbonylative addition of phthalic anhydrides to alkynes was exergonic, and the total free energy released was -87.6 kJ mol(-1). In the five-coordinated complexes M4a and M4b, the insertion reaction of alkynes into the Ni-C bond occurred prior to that into the Ni-O bond. The nickel(0)/zinc-catalyzed decarbonylative addition was much more dominant than the nickel-catalyzed one in whole catalytic decarbonylative addition. The reaction channel CA→M1'→T1'→M2'→T2'→M3a'→M4a'→T3a1'→M5a1' →T4a1'→M6a'→P was the most favorable among all reaction pathways of the nickel- or nickel(0)/zinc- catalyzed decarbonylative addition of phthalic anhydrides to alkynes. And the alkyne insertion reaction was the rate-determining step for this channel. The additive ZnCl2 had a significant effect, and it might change greatly the electron and geometry structures of those intermediates and transition states. On the whole, the solvent effect decreased the free energy barriers.

  20. Questionnaire established for the Brazilian inventory of low and intermediate level radioactive waste

    Energy Technology Data Exchange (ETDEWEB)

    Marumo, Julio T., E-mail: jtmarumo@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil); Silva, Fabio; Pinto, Antonio Juscelino, E-mail: silvaf@cdtn.br, E-mail: ajp@cdtn.br [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil); Taveira, Gerson L.S., E-mail: gersonluizst@gmail.com [Centro Federal de Educacao Tecnologica de Minas Gerais (CEFET-MG), Belo Horizonte, MG (Brazil). Engenharia de Producao Civil

    2015-07-01

    The Nuclear Technology Development Center (CDTN), an institute of Brazilian National Commission of Nuclear Energy (CNEN), is responsible for the technical coordination of the Brazilian Repository Project (RBMN), for Low and Intermediate Level Radioactive Wastes. To establish the inventory of the low and intermediate radioactive level waste to be disposed in the national Repository, a questionnaire was elaborated to be filled on line, via WEB, exclusively to registered users, which involved CNEN's institutes, ELETRONUCLEAR, INB and CTMSP. Based on all standardized information received from questionnaires, an easy use database to inventory the radioactive waste was created in Microsoft Access® that supported the calculation of the volume of radioactive waste treated and non-treated, stored and generated presently in Brazil. In addition, from this database it will be possible to establish some disposal procedures and the necessary area of construction. The objective of this work is to present this database and some general information about the radwastes in Brazil. (author)

  1. Therapeutic Cancer Vaccines in Prostate Cancer: The Quest for Intermediate Markers of Response

    International Nuclear Information System (INIS)

    Kim, Joseph W.; Bilusic, Marijo; Heery, Christopher J.; Madan, Ravi A.

    2012-01-01

    Despite recent advances in cancer immunotherapy, no prospectively validated intermediate biomarkers exist to predict response. These biomarkers are highly desirable given modern immunotherapy’s paradoxical pattern of clinical benefit; that is, improvement in overall survival without short-term change in progression. Immunotherapy clinical trials have evaluated biomarkers that may correlate with clinical outcomes. Many of them are performed on peripheral blood to evaluate the systemic response, such as tumor-targeted humoral and cellular immunity, and cytokine responses. Accumulating evidence suggests that immune infiltrates in tumors may suggest evidence for the therapy’s mechanism of action, and have greater potential for providing prognostic and predictive information. In addition, a non-immunologic biomarker, such as tumor growth kinetics, may explain this paradoxical pattern of clinical benefit, and predict survival in patients treated with an immunotherapy. Prospective assessment and validation of these and other intermediate markers would be required to better understand their potential clinical role

  2. Questionnaire established for the Brazilian inventory of low and intermediate level radioactive waste

    International Nuclear Information System (INIS)

    Marumo, Julio T.; Silva, Fabio; Pinto, Antonio Juscelino; Taveira, Gerson L.S.

    2015-01-01

    The Nuclear Technology Development Center (CDTN), an institute of Brazilian National Commission of Nuclear Energy (CNEN), is responsible for the technical coordination of the Brazilian Repository Project (RBMN), for Low and Intermediate Level Radioactive Wastes. To establish the inventory of the low and intermediate radioactive level waste to be disposed in the national Repository, a questionnaire was elaborated to be filled on line, via WEB, exclusively to registered users, which involved CNEN's institutes, ELETRONUCLEAR, INB and CTMSP. Based on all standardized information received from questionnaires, an easy use database to inventory the radioactive waste was created in Microsoft Access® that supported the calculation of the volume of radioactive waste treated and non-treated, stored and generated presently in Brazil. In addition, from this database it will be possible to establish some disposal procedures and the necessary area of construction. The objective of this work is to present this database and some general information about the radwastes in Brazil. (author)

  3. Therapeutic Cancer Vaccines in Prostate Cancer: The Quest for Intermediate Markers of Response

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Joseph W.; Bilusic, Marijo; Heery, Christopher J.; Madan, Ravi A., E-mail: madanr@mail.nih.gov [Laboratory of Tumor Immunology and Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 (United States); Medical Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 (United States)

    2012-11-21

    Despite recent advances in cancer immunotherapy, no prospectively validated intermediate biomarkers exist to predict response. These biomarkers are highly desirable given modern immunotherapy’s paradoxical pattern of clinical benefit; that is, improvement in overall survival without short-term change in progression. Immunotherapy clinical trials have evaluated biomarkers that may correlate with clinical outcomes. Many of them are performed on peripheral blood to evaluate the systemic response, such as tumor-targeted humoral and cellular immunity, and cytokine responses. Accumulating evidence suggests that immune infiltrates in tumors may suggest evidence for the therapy’s mechanism of action, and have greater potential for providing prognostic and predictive information. In addition, a non-immunologic biomarker, such as tumor growth kinetics, may explain this paradoxical pattern of clinical benefit, and predict survival in patients treated with an immunotherapy. Prospective assessment and validation of these and other intermediate markers would be required to better understand their potential clinical role.

  4. Final Technical Report: Vibrational Spectroscopy of Transient Combustion Intermediates Trapped in Helium Nanodroplets

    Energy Technology Data Exchange (ETDEWEB)

    Douberly, Gary Elliott [Univ. of Georgia, Athens, GA (United States)

    2017-11-16

    The objective of our experimental research program is to isolate and stabilize transient intermediates and products of prototype combustion reactions. This will be accomplished by Helium Nanodroplet Isolation, a novel technique where liquid helium droplets freeze out high energy metastable configurations of a reacting system, permitting infrared spectroscopic characterizations of products and intermediates that result from hydrocarbon radical reactions with molecular oxygen and other small molecules relevant to combustion environments. The low temperature (0.4 K) and rapid cooling associated with He droplets provides a perfectly suited medium to isolate and probe a broad range of molecular radical and carbene systems important to combustion chemistry. The sequential addition of molecular species to He droplets often leads to the stabilization of high-energy, metastable cluster configurations that represent regions of the potential energy surface far from the global minimum. Single and double resonance IR laser spectroscopy techniques, along with Stark and Zeeman capabilities, are being used to probe the structural and dynamical properties of these systems.

  5. Intermediate energy data

    International Nuclear Information System (INIS)

    Koning, A.J.; Fukahori, T.; Hasegawa, A.

    1998-01-01

    Subgroup 13 (SG13) on Intermediate Energy Nuclear data was formed by NEA Nuclear Science Committee to solve common problems of these types of data for nuclear applications. An overview is presented in this final report of the present activities of SG13, including data needs, high-priority nuclear data request list (nuclides), compilation of experimental data, specialists meetings and benchmarks, data formats and data libraries. Some important accomplishments are summarized, and recommendations are presented. (R.P.)

  6. Has Banks’ Financial Intermediation Improved in Russia?

    OpenAIRE

    Fungachova, Z.; Solanko, L.

    2010-01-01

    The aim of this paper is to analyze the increasing importance of banks in the Russian economy over the period following the financial crisis of 1998. We use several measures to assess the role of banks in domestic financial intermediation in Russia. The traditional macro-level view is complemented by the analysis of sectoral financial flows as well as by insights from micro-level studies. All of these confirm that banks are becoming increasingly important in financial intermediation. We find ...

  7. The Rheology of the Earth in the Intermediate Time Range

    Directory of Open Access Journals (Sweden)

    A. E. SCHEIDEGGER

    1970-06-01

    Full Text Available The evidence bearing upon the rheology of the " tectonically
    significant layers" of the Earth (" tectonosphere " in the intermediate
    time range (4 hours to 15000 years is analyzed. This evidence is
    based upon observations of rock-behavior in the laboratory, of seismic
    aftershock sequences, of Earth tides and of the decay of the Chandler wobble.
    It is shown that of the rheological models (Maxwell-material, Kelvin-material,
    and logarithmically creeping material advocated in the literature, only that
    based on logarithmic creep does not contradict any of the observational
    evidence available to date. In addition, a strength limit may be present.

  8. MONETARY POLICIES AND INDUSTRIAL FLUCTUATIONS IN EAST EUROPEAN COUNTRIES

    Directory of Open Access Journals (Sweden)

    Mihaela IFRIM

    2015-03-01

    Full Text Available Industrial fluctuations are closely related to the evolution of relative prices of produced goods and resources involved in production activity. Industrial fluctuations, as an expression of forces manifested in the real economy, are caused by changes in individuals’ consumption and investment decisions, produced within expansionary monetary policies. The ease of obtaining a bank loan in the context of decreasing interest rates and of larger amounts of money caused an increase in individuals’ demand for goods resulted from longer, capital intensive production processes. The rise in prices of intermediate and capital goods in a faster pace compared to the increase in prices of consumer goods is doubled by the increase of the share of higher order industries in the structure of production. The objective of this paper is to analyze changes in industrial structure of Eastern Europe countries within the policies of quick access to monetary resources. The analyzed states (Bulgaria, the Czech Republic, Hungary, Poland and Romania are part of the European Union and have autonomous monetary policies, meaning that they have not yet adopted the common currency. In all economies analyzed, we find approximately the same patterns of monetary expansion and industrial fluctuations.

  9. Data Speak: Influencing School Health Policy through Research

    Science.gov (United States)

    Ryberg, Jacalyn Wickline; Keller, Teresa; Hine, Beverly; Christeson, Elisabeth

    2003-01-01

    School nurses occupy a unique position in relation to school health policy. In addition to facing the demands of promoting and maintaining the health of students, they collect the information that is used to document the implementation of school health policy. Effective school health policy is guided by reliable, credible data regarding what…

  10. Metabolic and functional diversity of saponins, biosynthetic intermediates and semi-synthetic derivatives

    Science.gov (United States)

    Moses, Tessa; Papadopoulou, Kalliope K.

    2014-01-01

    Saponins are widely distributed plant natural products with vast structural and functional diversity. They are typically composed of a hydrophobic aglycone, which is extensively decorated with functional groups prior to the addition of hydrophilic sugar moieties, to result in surface-active amphipathic compounds. The saponins are broadly classified as triterpenoids, steroids or steroidal glycoalkaloids, based on the aglycone structure from which they are derived. The saponins and their biosynthetic intermediates display a variety of biological activities of interest to the pharmaceutical, cosmetic and food sectors. Although their relevance in industrial applications has long been recognized, their role in plants is underexplored. Recent research on modulating native pathway flux in saponin biosynthesis has demonstrated the roles of saponins and their biosynthetic intermediates in plant growth and development. Here, we review the literature on the effects of these molecules on plant physiology, which collectively implicate them in plant primary processes. The industrial uses and potential of saponins are discussed with respect to structure and activity, highlighting the undoubted value of these molecules as therapeutics. PMID:25286183

  11. 32 CFR 636.8 - Registration policy.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Registration policy. 636.8 Section 636.8 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW ENFORCEMENT AND CRIMINAL INVESTIGATIONS MOTOR VEHICLE TRAFFIC SUPERVISION (SPECIFIC INSTALLATIONS) Fort Stewart, Georgia § 636.8 Registration policy. In addition to th...

  12. Heterophobia: Subverting Heterosexual Hegemony through Intermedial Applied Performance for Young People

    Science.gov (United States)

    Phillips, Hannah

    2016-01-01

    This article responds to intermediality through a case study of an intermedial applied performance for young people. "Heterophobia," a hybrid fusion of live performance, digital technology, social media and urban street art, aimed to challenge homophobia in schools and online. Intermediality was used as a tool to enhance young people's…

  13. 42 CFR 54a.12 - Treatment of intermediate organizations.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Treatment of intermediate organizations. 54a.12... CHARITABLE CHOICE REGULATIONS APPLICABLE TO STATES, LOCAL GOVERNMENTS AND RELIGIOUS ORGANIZATIONS RECEIVING... ABUSE PREVENTION AND TREATMENT SERVICES § 54a.12 Treatment of intermediate organizations. If a...

  14. Financial Intermediation and the Nigerian Economy: A Time Series ...

    African Journals Online (AJOL)

    ... and cointegration analysis based on Engle Granger cointegration theory and error correction methodology, we tested both short and long run relationships between financial intermediation and economic growth in Nigeria. The result revealed that a long–run relationship exists between financial intermediation and growth ...

  15. Borderline Personality Disorder in an Intermediate Psychological Therapies Service

    Science.gov (United States)

    Ryan, Seamus; Danquah, Adam N.; Berry, Katherine; Hopper, Mary

    2017-01-01

    The intermediate psychological therapies service is provided for individuals referred with common mental health problems within the primary care psychological therapies service, but whose difficulties are longstanding and/or complex. The prevalence of borderline personality disorder (BPD) in intermediate psychological therapy services has not been…

  16. General educational disciplines practice-oriented training in intermediate vocational education

    Directory of Open Access Journals (Sweden)

    Liya G. Skorobogatova

    2011-01-01

    Full Text Available The article concerns crucial issues of practice-oriented training in Russia's intermediate vocational education, designates directions of general educational disciplines study in intermediate vocational education.

  17. Intermediate inflation from a non-canonical scalar field

    Energy Technology Data Exchange (ETDEWEB)

    Rezazadeh, K.; Karami, K. [Department of Physics, University of Kurdistan, Pasdaran St., Sanandaj (Iran, Islamic Republic of); Karimi, P., E-mail: rezazadeh86@gmail.com, E-mail: KKarami@uok.ac.ir, E-mail: parvin.karimi67@yahoo.com [Center for Excellence in Astronomy and Astrophysics (CEAA-RIAAM), P.O. Box 55134-441, Maragha (Iran, Islamic Republic of)

    2015-09-01

    We study the intermediate inflation in a non-canonical scalar field framework with a power-like Lagrangian. We show that in contrast with the standard canonical intermediate inflation, our non-canonical model is compatible with the observational results of Planck 2015. Also, we estimate the equilateral non-Gaussianity parameter which is in well agreement with the prediction of Planck 2015. Then, we obtain an approximation for the energy scale at the initial time of inflation and show that it can be of order of the Planck energy scale, i.e. M{sub P} ∼ 10{sup 18}GeV. We will see that after a short period of time, inflation enters in the slow-roll regime that its energy scale is of order M{sub P}/100 ∼ 10{sup 16}GeV and the horizon exit takes place in this energy scale. We also examine an idea in our non-canonical model to overcome the central drawback of intermediate inflation which is the fact that inflation never ends. We solve this problem without disturbing significantly the nature of the intermediate inflation until the time of horizon exit.

  18. Estimation of intermediate grade uranium resources. Final report

    International Nuclear Information System (INIS)

    Lambie, F.W.; Kendall, G.R.; Klahn, L.J.; Davis, J.C.; Harbaugh, J.W.

    1980-12-01

    The purpose of this project is to analyze the technique currently used by DOE to estimate intermediate grade uranium (0.01 to 0.05% U 3 O 8 ) and, if possible, suggest alternatives to improve the accuracy and precision of the estimate. There are three principal conclusions resulting from this study. They relate to the quantity, distribution and sampling of intermediate grade uranium. While the results of this study must be validated further, they indicate that DOE may be underestimating intermediate level reserves by 20 to 30%. Plots of grade of U 3 O 8 versus tonnage of ore and tonnage U 3 O 8 indicate grade-tonnage relationships that are essentially log-linear, at least down to 0.01% U 3 O 8 . Though this is not an unexpected finding, it may provide a technique for reducing the uncertainty of intermediate grade endowment. The results of this study indicate that a much lower drill hole density is necessary for DOE to estimate uranium resources than for a mining company to calculate ore resources. Though errors in local estimates will occur, they will tend to cancel over the entire deposit

  19. Balanced activation of IspG and IspH to eliminate MEP intermediate accumulation and improve isoprenoids production in Escherichia coli.

    Science.gov (United States)

    Li, Qingyan; Fan, Feiyu; Gao, Xiang; Yang, Chen; Bi, Changhao; Tang, Jinlei; Liu, Tao; Zhang, Xueli

    2017-11-01

    The MEP pathway genes were modulated to investigate whether there were new rate-limiting steps and toxic intermediates in this pathway. Activating IspG led to significant decrease of cell growth and β-carotene production. It was found that ispG overexpression led to accumulation of intermediate HMBPP, which seriously interfered with synthesis machinery of nucleotide and protein in Escherichia coli. Activation of the downstream enzyme IspH could solve HMBPP accumulation problem and eliminate the negative effects of ispG overexpression. In addition, intermediate MECPP accumulated in the starting strain, while balanced activation of IspG and IspH could push the carbon flux away from MECPP and led to 73% and 77% increase of β-carotene and lycopene titer respectively. Our work for the first time identified HMBPP to be a cytotoxic intermediate in MEP pathway and demonstrated that balanced activation of IspG and IspH could eliminate accumulation of HMBPP and MECPP and improve isoprenoids production. Copyright © 2017 International Metabolic Engineering Society. Published by Elsevier Inc. All rights reserved.

  20. Structure of replicating intermediates of human herpesvirus type 6

    International Nuclear Information System (INIS)

    Severini, Alberto; Sevenhuysen, Claire; Garbutt, Michael; Tipples, Graham A.

    2003-01-01

    We have studied the structure of the replicative intermediates of human herpesvirus 6 (HHV-6) using pulsed-field gel electrophoresis, partial digestion, two-dimensional gel electrophoresis, and sedimentation centrifugation. The results show that DNA replication of HHV-6 produces head-to-tail concatemeric intermediates as well as approximately equal amounts of circular monomers or oligomers. Unlike the situation in herpes simplex virus, the intermediates of human herpesvirus 6 replication are not highly branched, suggesting a difference in the mechanism of replication or a lower frequency of homologous recombination in human herpesvirus 6 compared to herpes simplex virus

  1. Mechanisms of deterioration of intermediate moisture food systems

    Science.gov (United States)

    Labuza, T. P.

    1972-01-01

    A study of shelf stability in intermediate moisture foods was made. Major efforts were made to control lipid oxidation and nonenzymatic browning. In order to determine means of preventing these reactions, model systems were developed having the same water activity content relationship of intermediate moisture foods. Models were based on a cellulose-lipid and protein-lipid system with glycerol added as the humectant. Experiments with both systems indicate that lipid oxidation is promoted significantly in the intermediate moisture range. The effect appeared to be related to increased mobility of either reactants or catalysts, since when the amount of water in the system reached a level where capillary condensation occurred and thus free water was present, the rates of oxidation increased. With added glycerol, which is water soluble and thus increases the amount of mobile phase, the increase in oxidation rate occurs at a lower relative humidity. The rates of oxidation were maximized at 61% RH and decreased again at 75% RH probably due to dilution. No significant non-enzymatic browning occurred in the protein-lipid systems. Prevention of oxidation by the use of metal chelating agents was enhanced in the cellulose system, whereas, with protein present, the lipid soluble chain terminating antioxidants (such as BHA) worked equally as well. Preliminary studies of foods adjusted to the intermediate moisture range bear out the results of oxidation in model systems. It can be concluded that for most fat containing intermediate moisture foods, rancidity will be the reaction most limiting stability.

  2. Policy analysis: palliative care in Ireland.

    LENUS (Irish Health Repository)

    Larkin, P

    2014-03-01

    Palliative care for patients with advanced illness is a subject of growing importance in health services, policy and research. In 2001 Ireland became one of the first nations to publish a dedicated national palliative care policy. This paper uses the \\'policy analysis triangle\\' as a framework to examine what the policy entailed, where the key ideas originated, why the policy process was activated, who were the key actors, and what were the main consequences. Although palliative care provision expanded following publication, priorities that were unaddressed or not fully embraced on the national policy agenda are identified. The factors underlying areas of non-fulfilment of policy are then discussed. In particular, the analysis highlights that policy initiatives in a relatively new field of healthcare face a trade-off between ambition and feasibility. Key policy goals could not be realised given the large resource commitments required; the competition for resources from other, better-established healthcare sectors; and challenges in expanding workforce and capacity. Additionally, the inherently cross-sectoral nature of palliative care complicated the co-ordination of support for the policy. Policy initiatives in emerging fields such as palliative care should address carefully feasibility and support in their conception and implementation.

  3. The Vietnamese lending rate, policy-related rate, and monetary policy post-1997 Asian financial crisis

    Directory of Open Access Journals (Sweden)

    Chu V. Nguyen

    2015-12-01

    Full Text Available Asymmetries in the Vietnamese lending central bank’s policy-related rate spread were documented. Empirical results revealed that the spread adjusts to the threshold faster when the central bank’s policy-related rates decrease relative to the lending rates than when the central bank’s policy-related rates move in the opposite direction. Additionally, the empirical findings indicate that Vietnamese commercial banks exhibit competitive rate setting behavior which may be attributable to graft maximization by bank’s management. The results also show bidirectional Granger causality between the Vietnamese lending rate and the central bank’s policy-related rate, indicating that the lending rate and the central bank’s policy-related rate affect each other’s movements. These results suggest that monetary authority can use its countercyclical monetary policy instruments to achieve its macroeconomics objectives. However, the estimation results of the GARCH (2, 3-in-Mean model suggest that they should intervene more frequently and by small policy measures to minimize the conditional variance of the spread to minimize the magnitude of the cycle of the lending rate.

  4. Mediterranean intermediate circulation estimated from Argo data in 2003–2010

    Directory of Open Access Journals (Sweden)

    M. Menna

    2010-03-01

    Full Text Available Data from 38 Argo profiling floats are used to describe the intermediate Mediterranean currents for the period October 2003–January 2010. These floats were programmed to execute 5-day cycles, to drift at a neutral parking depth of 350 m and measure temperature and salinity profiles from either 700 or 2000 m up to the surface. At the end of each cycle the floats remained at the sea surface for about 6 h, enough time to be localised and transmit the data to the Argos satellite system. The Argos positions were used to determine the float surface and intermediate displacements. At the surface, the float motion was approximated by a linear displacement and inertial motion. Intermediate velocities estimates were used to investigate the Mediterranean circulation at 350 m, to compute the pseudo-Eulerian statistics and to study the influence of bathymetry on the intermediate currents. Maximum speeds, as large as 33 cm/s, were found northeast of the Balearic Islands (western basin and in the Ierapetra eddy (eastern basin. Typical speeds in the main along-slope currents (Liguro-Provençal-Catalan, Algerian and Libyo-Egyptian Currents were ~20 cm/s. In the central and western part of Mediterranean basin, the pseudo-Eulerian statistics show typical intermediate circulation pathways which can be related to the motion of Levantine Intermediate Water. In general our results agree with the qualitative intermediate circulation schemes proposed in the literature, except in the southern Ionian where we found westward-flowing intermediate currents. Fluctuating currents appeared to be usually larger than the mean flow. Intermediate currents were found to be essentially parallel to the isobaths over most of the areas characterized by strong bathymetry gradients, in particular, in the vicinity of the continental slopes.

  5. Short, intermediate and long range order in amorphous ices

    Science.gov (United States)

    Martelli, Fausto; Torquato, Salvatore; Giovanbattista, Nicolas; Car, Roberto

    Water exhibits polyamorphism, i.e., it exists in more than one amorphous state. The most common forms of glassy water are the low-density amorphous (LDA) and the high-density amorphous (HDA) ices. LDA, the most abundant form of ice in the Universe, transforms into HDA upon isothermal compression. We model the transformation of LDA into HDA under isothermal compression with classical molecular dynamics simulations. We analyze the molecular structures with a recently introduced scalar order metric to measure short and intermediate range order. In addition, we rank the structures by their degree of hyperuniformity, i.e.,the extent to which long range density fluctuations are suppressed. F.M. and R.C. acknowledge support from the Department of Energy (DOE) under Grant No. DE-SC0008626.

  6. Fleet dynamics in a changing policy environment

    NARCIS (Netherlands)

    Batsleer, J.

    2016-01-01

    The European Common Fisheries Policy has received much criticism. In the first place for failing to implement effective management measures aimed at rebuilding and maintaining fish stocks at a sustainable level. In addition, it is said current fisheries policy fails to integrate the wider

  7. Intermediate Collaborative Adaptive Management Strategies Build Stakeholder Capacity

    Directory of Open Access Journals (Sweden)

    Martha C. Monroe

    2013-06-01

    Full Text Available Efforts to implement collaborative adaptive management (CAM often suffer from challenges, such as an unwillingness of managers to share power, unresolved conflicts between stakeholders, and lack of capacity among stakeholders. Some aspects considered essential to CAM, e.g., trust and stakeholder capacity, may be more usefully viewed as goals for intermediate strategies rather than a set of initial conditions. From this perspective, intermediate steps that focus on social learning and building experience could overcome commonly cited barriers to CAM. An exploration of Springs Basin Working Groups, organized around major clusters of freshwater springs in north Florida, provides a case study of how these intermediate steps enable participants to become more reasonable and engaged. This strategy may be easily implemented by agencies beginning a CAM process.

  8. Formation of intermediate shocks in both two-fluid and hybrid models

    International Nuclear Information System (INIS)

    Wu, C.C.; Hada, T.

    1991-01-01

    Intermediate shocks are shocks with shock frame fluid velocities greater than the Alfven speed ahead and less than the Alfven speed behind, or equivalently, across intermediate shocks the sign of the transverse component of the magnetic field changes. These shocks had been considered extraneous, or nonevolutionary, or unstable, and they had been thought not to correspond to physical reality [Germain, 1960; Jeffrey and Taniuti, 1964; Kantrowitz and Petschek, 1966]. However, it has been shown that intermediate shocks can be formed from continuous waves according to dissipative magnetohydrodynamics (MHD) [Wu, 1987, 1988a, b, 1990]. Thus according to the formation argument which requires that physical shocks be formed by the wave steepening process, the intermediate shocks should be considered physical. Here, intermediate shocks are studied in a two-fluid model that includes finite ion inertia dispersion and in a hybrid model in which the full ion dynamics is retained while the electrons are treated as a massless fluid. The authors show that in both models intermediate shocks can be formed through wave steepening, meaning that they are stable and possess shock structures

  9. Identification of an Unfolding Intermediate for a DNA Lesion Bypass Polymerase

    Science.gov (United States)

    Sherrer, Shanen M.; Maxwell, Brian A.; Pack, Lindsey R.; Fiala, Kevin A.; Fowler, Jason D.; Zhang, Jun; Suo, Zucai

    2012-01-01

    Sulfolobus solfataricusDNA Polymerase IV (Dpo4), a prototype Y-family DNA polymerase, has been well characterized biochemically and biophysically at 37 °C or lower temperatures. However, the physiological temperature of the hyperthermophile S. solfataricus is approximately 80 °C. With such a large discrepancy in temperature, the in vivo relevance of these in vitro studies of Dpo4 has been questioned. Here, we employed circular dichroism spectroscopy and fluorescence-based thermal scanning to investigate the secondary structural changes of Dpo4 over a temperature range from 26 to 119 °C. Dpo4 was shown to display a high melting temperature characteristic of hyperthermophiles. Unexpectedly, the Little Finger domain of Dpo4, which is only found in the Y-family DNA polymerases, was shown to be more thermostable than the polymerase core. More interestingly, Dpo4 exhibited a three-state cooperative unfolding profile with an unfolding intermediate. The linker region between the Little Finger and Thumb domains of Dpo4 was found to be a source of structural instability. Through site-directed mutagenesis, the interactions between the residues in the linker region and the Palm domain were identified to play a critical role in the formation of the unfolding intermediate. Notably, the secondary structure of Dpo4 was not altered when the temperature was increased from 26 to 87.5 °C. Thus, in addition to providing structural insights into the thermal stability and an unfolding intermediate of Dpo4, our work also validated the relevance of the in vitro studies of Dpo4 performed at temperatures significantly lower than 80 °C. PMID:22667759

  10. Regioselectivity of conjugate additions to monoalkyl-1,4-benzoquinones

    Directory of Open Access Journals (Sweden)

    SNEZANA TRIFUNOVIC

    2002-09-01

    Full Text Available The regioselectivity of the reaction of conjugate addition of thiols, amines, methanol and hydrogen chloride with the monoalkyl-1,4-benzoquinones avarone and 2-tert-butyl-1,4-benzoquinone was investigated. It was shown that the regioselectivity of the reaction is influenced by the electrophilicity of position 5 in unprotonated 2-alkylquinones, the increased electrophilicity of position 6 in acidic medium, and by the acidity of the intermediate hydroquinones.

  11. A new intermediate for the production of flexible stable polymers

    Science.gov (United States)

    Webster, J. A.

    1973-01-01

    Method of incorporating ether linkages into perfluoroalkylene segment of a dianydride intermediate yields intermediate that may be used in synthesis of flexible, stable polyimides for use as high-temperature, solvent-resistant sealants.

  12. The Policy Context

    DEFF Research Database (Denmark)

    Panagakos, George

    2016-01-01

    Green project. The term ‘green’ is used in the sustainability context, meaning that it features economic and social dimensions in addition to the usual environmental one. The most important EU transport policy documents are reviewed and briefly presented by transportation mode. Horizontal documents covering all...

  13. Intermediate heat exchanger for HTR process heat application

    International Nuclear Information System (INIS)

    Crambes, M.

    1980-01-01

    In the French study on the nuclear gasification of coal, the following options were recommended: Coal hydrogenation, the hydrogen being derived from CH 4 reforming under the effects of HTR heat; the use of an intermediate helium circuit between the nuclear plant and the reforming plant. The purpose of the present paper is to describe the heat exchanger designed to transfer heat from the primary to the intermediate circuit

  14. Shelf stable intermediate moisture fruit cubes using radiation technology

    International Nuclear Information System (INIS)

    Mishra, Bibhuti B.; Saxena, Sudhanshu; Gautam, Satyendra; Chander, Ramesh; Sharma, Arun

    2009-01-01

    A process has been developed to prepare shelf stable ready-to-eat (RTE) intermediate moisture pineapple slices and papaya cubes using radiation technology. The combination of hurdles including osmotic dehydration, blanching, infrared drying, and gamma radiation dose of 1 kGy successfully reduced the microbial load to below detectable limit. The shelf life of the intermediate moisture pineapple slices and papaya cubes was found to be 40 days at ambient temperature (28 ± 2 deg C). The control samples spoiled within 6 days. The RTE intermediate moisture fruit products were found to have good texture, colour and sensory acceptability during this 40 days storage. (author)

  15. Monetary policy transmission mechanism in Poland. What do we know in 2011?

    OpenAIRE

    Tomasz Łyziak; Oksana Demchuk; Jan Przystupa; Anna Sznajderska; Ewa Wróbel

    2012-01-01

    In the light of the results of empirical studies presented in the Report and the literature available45 it may be concluded that the form of the monetary policy transmission mechanism in Poland is consistent with structural features of the Polish economy and coincides with those characteristic of more developed European economies, e.g. the euro area. Although the financial intermediation system is less developed than in the euro area, Poland, like the new EU Member States is characterised by ...

  16. Healthy Food Procurement Policies and Their Impact

    Science.gov (United States)

    Niebylski, Mark L.; Lu, Tammy; Campbell, Norm R. C.; Arcand, Joanne; Schermel, Alyssa; Hua, Diane; Yeates, Karen E.; Tobe, Sheldon W.; Twohig, Patrick A.; L’Abbé, Mary R.; Liu, Peter P.

    2014-01-01

    Unhealthy eating is the leading risk for death and disability globally. As a result, the World Health Organization (WHO) has called for population health interventions. One of the proposed interventions is to ensure healthy foods are available by implementing healthy food procurement policies. The objective of this systematic review was to evaluate the evidence base assessing the impact of such policies. A comprehensive review was conducted by searching PubMed and Medline for policies that had been implemented and evaluated the impact of food purchases, food consumption, and behaviors towards healthy foods. Thirty-four studies were identified and found to be effective at increasing the availability and purchases of healthy food and decreasing purchases of unhealthy food. Most policies also had other components such as education, price reductions, and health interventions. The multiple gaps in research identified by this review suggest that additional research and ongoing evaluation of food procurement programs is required. Implementation of healthy food procurement policies in schools, worksites, hospitals, care homes, correctional facilities, government institutions, and remote communities increase markers of healthy eating. Prior or simultaneous implementation of ancillary education about healthy eating, and rationale for the policy may be critical success factors and additional research is needed. PMID:24595213

  17. Material Voices: Intermediality and Autism

    Science.gov (United States)

    Trimingham, Melissa; Shaughnessy, Nicola

    2016-01-01

    Autism continues to be regarded enigmatically; a community that is difficult to access due to perceived disruptions of interpersonal connectedness. Through detailed observations of two children participating in the Arts and Humanities Research Council funded project "Imagining Autism: Drama, Performance and Intermediality as Interventions for…

  18. Insignificant disease among men with intermediate-risk prostate cancer.

    Science.gov (United States)

    Hong, Sung Kyu; Vertosick, Emily; Sjoberg, Daniel D; Scardino, Peter T; Eastham, James A

    2014-12-01

    A paucity of data exists on the insignificant disease potentially suitable for active surveillance (AS) among men with intermediate-risk prostate cancer (PCa). We tried to identify pathologically insignificant disease and its preoperative predictors in men who underwent radical prostatectomy (RP) for intermediate-risk PCa. We analyzed data of 1,630 men who underwent RP for intermediate-risk disease. Total tumor volume (TTV) data were available in 332 men. We examined factors associated with classically defined pathologically insignificant cancer (organ-confined disease with TTV ≤0.5 ml with no Gleason pattern 4 or 5) and pathologically favorable cancer (organ-confined disease with no Gleason pattern 4 or 5) potentially suitable for AS. Decision curve analysis was used to assess clinical utility of a multivariable model including preoperative variables for predicting pathologically unfavorable cancer. In the entire cohort, 221 of 1,630 (13.6 %) total patients had pathologically favorable cancer. Among 332 patients with TTV data available, 26 (7.8 %) had classically defined pathologically insignificant cancer. Between threshold probabilities of 20 and 40 %, decision curve analysis demonstrated that using multivariable model to identify AS candidates would not provide any benefit over simply treating all men who have intermediate-risk disease with RP. Although a minority of patients with intermediate-risk disease may harbor pathologically favorable or insignificant cancer, currently available conventional tools are not sufficiently able to identify those patients.

  19. Multifragmentation in intermediate energy heavy ion collisions

    International Nuclear Information System (INIS)

    Jacak, B.V.; Britt, H.C.; Claesson, G.

    1986-01-01

    There has been considerable recent interest in the production of intermediate mass fragments (A > 4) in intermediate and high energy nucleus-nucleus collisions. The mechanism for production of these fragments is not well understood and has been described by models employing a variety of assumptions. Some examples are: disassembly of a system in thermal equilibrium into nucleons and nuclear fragments, liquid-vapor phase transitions in nuclear matter, final state coalescence of nucleons and dynamical correlations between nucleons at breakup. Previous studies of fragment production, with one exception, have been single particle inclusive measurements; the observed fragment mass (or charge) distributions can be described by all of the models above. To gain insight into the fragment production mechanism, the authors used the GSI/LBL Plastic Ball detector system to get full azimuthal coverage for intermediate mass fragments in the forward hemisphere in the center of mass system while measuring all the light particles in each event. The authors studied the systems 200 MeV/nucleon Au + Au and Au + Fe

  20. Intermediate, low, and very low level waste management at ANDRA (agence nationale pour la gestion des dechets radioactifs) in France

    International Nuclear Information System (INIS)

    Senoo, Muneaki

    2005-01-01

    On 28th September in 2004, RANDEC invited Mr. Jean-Louis Tison from ANDRA as a lecturer of the special session of the 16th RANDEC Annual Symposium. An ANDRA-RANDEC technical meeting was held on the next day, where Mr. Vincent Carlier invited from ANDRA, too participated. Here, present status of intermediate, low, and very low level waste management in France is reviewed based on the information which were obtained from the special session of the 16th RANDEC Annual Symposium and the ANDRA-RANDEC technical meeting. In France, ANDRA is implementing radioactive waste management under the following policy; 'Intermediate, low, and very-low-level (ILVLL) waste is managed in order to establish as soon as possible a final disposal system, the temporary or long term storage option being considered only for the high-level waste (HLW) such as the vitrified fission products or particular materials such as some sealed sources for which no final disposal solution still exists.' The Agency is financed on the basis of the 'polluter-pays' principle and contracts its services directly with waste owners. (author)

  1. Intermediate-energy neutron beam for NCT at MURR

    International Nuclear Information System (INIS)

    Brugger, R.M.; Less, T.J.; Passmore, G.G.

    1986-01-01

    The University of Missouri Research Reactor (MURR) is one of the high-flux reactors in the USA and it can be used to produce an intense beam of intermediate-energy neutrons for neutron capture therapy. Two methods are being evaluated at MURR to produce such a beam. The first uses a moderator of Al 2 O 3 replacing part of the graphite and water on one side of the core of the reactor to produce a source of predominantly intermediate-energy neutrons. The second method is a filter of 238 U between the core and the patient position to pass only intermediate-energy neutrons. The results of these evaluations are presented in this paper along with an outline of the other resources at the University of Missouri-Columbia that are available to support an NCT program. 4 references, 7 figures, 1 table

  2. Differential role of calpain-dependent protein cleavage in intermediate and long-term operant memory in Aplysia.

    Science.gov (United States)

    Lyons, Lisa C; Gardner, Jacob S; Lentsch, Cassidy T; Gandour, Catherine E; Krishnan, Harini C; Noakes, Eric J

    2017-01-01

    In addition to protein synthesis, protein degradation or protein cleavage may be necessary for intermediate (ITM) and long-term memory (LTM) to remove molecular constraints, facilitate persistent kinase activity and modulate synaptic plasticity. Calpains, a family of conserved calcium dependent cysteine proteases, modulate synaptic function through protein cleavage. We used the marine mollusk Aplysia californica to investigate the in vivo role of calpains during intermediate and long-term operant memory formation using the learning that food is inedible (LFI) paradigm. A single LFI training session, in which the animal associates a specific netted seaweed with the failure to swallow, generates short (30min), intermediate (4-6h) and long-term (24h) memory. Using the calpain inhibitors calpeptin and MDL-28170, we found that ITM requires calpain activity for induction and consolidation similar to the previously reported requirements for persistent protein kinase C activity in intermediate-term LFI memory. The induction of LTM also required calpain activity. In contrast to ITM, calpain activity was not necessary for the molecular consolidation of LTM. Surprisingly, six hours after LFI training we found that calpain activity was necessary for LTM, although this is a time at which neither persistent PKC activity nor protein synthesis is required for the maintenance of long-term LFI memory. These results demonstrate that calpains function in multiple roles in vivo during associative memory formation. Copyright © 2016 Elsevier Inc. All rights reserved.

  3. 48 CFR 810.001 - Market research policy.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Market research policy... COMPETITION AND ACQUISITION PLANNING MARKET RESEARCH 810.001 Market research policy. When conducting market research, VA contracting teams shall use the VIP database, at http://www.VetBiz.gov, in addition to other...

  4. Thermogravimetric control of intermediate compounds in uranium metallurgy

    International Nuclear Information System (INIS)

    Gasco Sanchez, L.; Fernandez Cellini, R.

    1959-01-01

    The thermal decomposition of some intermediate compounds in the metallurgy of the uranium as uranium peroxide, ammonium uranate, uranium and ammonium penta-fluoride, uranium tetrafluoride and uranous oxide has been study by means of the Chevenard's thermo balance. Some data on pyrolysis of synthetic mixtures of intermediate compounds which may occasionally appear during the industrial process, are given. Thermogravimetric methods of control are suggested, usable in interesting products in the uranium metallurgy. (Author) 20 refs

  5. Intermediate-energy neutron beams from reactors for NCT

    International Nuclear Information System (INIS)

    Brugger, R.M.; Less, T.J.; Passmore, G.G.

    1986-01-01

    This paper discusses ways that a beam of intermediate-energy neutrons might be extracted from a nuclear reactor. The challenge is to suppress the fast-neutron component and the gamma-ray component of the flux while leaving enough of the intermediate-energy neutrons in the beam to be able to perform neutron capture therapy in less than an hour exposure time. Moderators, filters, and reflectors are considered. 11 references, 7 figures, 3 tables

  6. Nucleic acid binding properties and intermediates of HCV core protein multimerization in Pichia pastoris

    International Nuclear Information System (INIS)

    Acosta-Rivero, Nelson; Rodriguez, Armando; Musacchio, Alexis; Falcon, Viviana; Suarez, Viana M.; Chavez, Liudmila; Morales-Grillo, Juan; Duenas-Carrera, Santiago

    2004-01-01

    Little is known about the in vivo assembly pathway or structure of the hepatitis C virus nucleocapsid. In this work the intermediates of HCcAg multimerization in Pichia pastoris cells and the nucleic acid binding properties of structured nucleocapsid-like particles (NLPs) were studied. Extensive cross-linking was observed for HCcAg after glutaraldehyde treatment. Data suggest that HCcAg exists in dimeric forms probably representing P21-P21, P21-P23, and P23-P23 dimers. In addition, the presence of HCcAg species that might represent trimers and multimers was observed. After sucrose equilibrium density gradient purification and nuclease digestion, NLPs were shown to contain both RNA and DNA molecules. Finally, the analysis by electron microscopy indicated that native NLPs were resistant to nuclease treatment. These results indicated that HCcAg assembles through dimers, trimers, and multimers' intermediates into capsids in P. pastoris cells. Assembly of NLPs in its natural environment might confer stability to these particles by adopting a compact structure

  7. Larval helminths in intermediate hosts

    DEFF Research Database (Denmark)

    Fredensborg, Brian Lund; Poulin, R

    2005-01-01

    Density-dependent effects on parasite fitness have been documented from adult helminths in their definitive hosts. There have, however, been no studies on the cost of sharing an intermediate host with other parasites in terms of reduced adult parasite fecundity. Even if larval parasites suffer a ...

  8. Drug policy, harm and human rights: a rationalist approach.

    Science.gov (United States)

    Stevens, Alex

    2011-05-01

    It has recently been argued that drug-related harms cannot be compared, so making it impossible to choose rationally between various drug policy options. Attempts to apply international human rights law to this area are valid, but have found it difficult to overcome the problems in applying codified human rights to issues of drug policy. This article applies the rationalist ethical argument of Gewirth (1978) to this issue. It outlines his argument to the 'principle of generic consistency' and the hierarchy of basic, nonsubtractive and additive rights that it entails. It then applies these ideas to drug policy issues, such as whether there is a right to use drugs, whether the rights of drug 'addicts' can be limited, and how different harms can be compared in choosing between policies. There is an additive right to use drugs, but only insofar as this right does not conflict with the basic and nonsubtractive rights of others. People whose freedom to choose whether to use drugs is compromised by compulsion have a right to receive treatment. They retain enforceable duties not to inflict harms on others. Policies which reduce harms to basic and nonsubtractive rights should be pursued, even if they lead to harms to additive rights. There exists a sound, rational, extra-legal basis for the discussion of drug policy and related harms which enables commensurable discussion of drug policy options. Copyright © 2011 Elsevier B.V. All rights reserved.

  9. Intermediate/Advanced Research Design and Statistics

    Science.gov (United States)

    Ploutz-Snyder, Robert

    2009-01-01

    The purpose of this module is To provide Institutional Researchers (IRs) with an understanding of the principles of advanced research design and the intermediate/advanced statistical procedures consistent with such designs

  10. Maximizing policy learning in international committees

    DEFF Research Database (Denmark)

    Nedergaard, Peter

    2007-01-01

    , this article demonstrates that valuable lessons can be learned about policy learning, in practice and theoretically, by analysing the cooperation in the OMC committees. Using the Advocacy Coalition Framework as the starting point of analysis, 15 hypotheses on policy learning are tested. Among other things......, it is concluded that in order to maximize policy learning in international committees, empirical data should be made available to committees and provided by sources close to the participants (i.e. the Commission). In addition, the work in the committees should be made prestigious in order to attract well...

  11. Thin-film intermediate band chalcopyrite solar cells

    International Nuclear Information System (INIS)

    Fuertes Marron, D.; Marti, A.; Luque, A.

    2009-01-01

    Chalcopyrite-based solar cells currently lead the efficiency tables of thin-film photovoltaic technologies. Further improvements are foreseen upon implementation of an intermediate band in the absorber layers. We present a theoretical analysis of the efficiency limit for this type of device as a function of factors such as the gap of the host, the relative position of the intermediate band with respect to the band edge and the level of light concentration used as illumination. We have also considered the impact of non-idealities on the performance of the device, particularly the effect of electronic losses related to non-radiative recombination

  12. Top predators induce the evolutionary diversification of intermediate predator species.

    Science.gov (United States)

    Zu, Jian; Yuan, Bo; Du, Jianqiang

    2015-12-21

    We analyze the evolutionary branching phenomenon of intermediate predator species in a tritrophic food chain model by using adaptive dynamics theory. Specifically, we consider the adaptive diversification of an intermediate predator species that feeds on a prey species and is fed upon by a top predator species. We assume that the intermediate predator׳s ability to forage on the prey can adaptively improve, but this comes at the cost of decreased defense ability against the top predator. First, we identify the general properties of trade-off relationships that lead to a continuously stable strategy or to evolutionary branching in the intermediate predator species. We find that if there is an accelerating cost near the singular strategy, then that strategy is continuously stable. In contrast, if there is a mildly decelerating cost near the singular strategy, then that strategy may be an evolutionary branching point. Second, we find that after branching has occurred, depending on the specific shape and strength of the trade-off relationship, the intermediate predator species may reach an evolutionarily stable dimorphism or one of the two resultant predator lineages goes extinct. Crown Copyright © 2015. Published by Elsevier Ltd. All rights reserved.

  13. Conditioning of intermediate-level waste at Forschungszentrum Juelich GmbH

    International Nuclear Information System (INIS)

    Krumbach, H.

    2003-01-01

    This contribution to the group of low-level, intermediate, mixed and hazardous waste describes the conditioning of intermediate-level mixed waste (dose rate above 10 mSv/h at the surface) from Research Centre Juelich (FZJ). Conditioning of the waste by supercompaction is performed at Research Centre Karlsruhe (FZK). The waste described is radioactive waste arising from research at Juelich. This waste includes specimens and objects from irradiation experiments in the research reactors Merlin (FRJ-1) and Dido (FRJ-2) at FZJ. In principle, radioactive waste at Forschungszentrum Juelich GmbH is differentiated by the surface dose rate at the waste package. Up to a surface dose rate of 10 mSv/h, the waste is regarded as low-level. The radioactive waste described here has a surface dose rate above 10 mSv/h. Waste up to 10 mSv/h is conditioned at the Juelich site according to different conditioning methods. The intermediate-level waste can only be conditioned by supercompaction in the processing facility for intermediate-level waste from plant operation at Research Centre Karlsruhe. Research Centre Juelich also uses this waste cell to condition its intermediate-level waste from plant operation. (orig.)

  14. Cryo-EM structures of two bovine adenovirus type 3 intermediates

    International Nuclear Information System (INIS)

    Cheng, Lingpeng; Huang, Xiaoxing; Li, Xiaomin; Xiong, Wei; Sun, Wei; Yang, Chongwen; Zhang, Kai; Wang, Ying; Liu, Hongrong; Huang, Xiaojun; Ji, Gang; Sun, Fei; Zheng, Congyi; Zhu, Ping

    2014-01-01

    Adenoviruses (Ads) infect hosts from all vertebrate species and have been investigated as vaccine vectors. We report here near-atomic structures of two bovine Ad type 3 (BAd3) intermediates obtained by cryo-electron microscopy. A comparison between the two intermediate structures reveals that the differences are localized in the fivefold vertex region, while their facet structures are identical. The overall facet structure of BAd3 exhibits a similar structure to human Ads; however, BAd3 protein IX has a unique conformation. Mass spectrometry and cryo-electron tomography analyses indicate that one intermediate structure represents the stage during DNA encapsidation, whilst the other intermediate structure represents a later stage. These results also suggest that cleavage of precursor protein VI occurs during, rather than after, the DNA encapsidation process. Overall, our results provide insights into the mechanism of Ad assembly, and allow the first structural comparison between human and nonhuman Ads at backbone level. - Highlights: • First structure of bovine adenovirus type 3. • Some channels are located at the vertex of intermediate during DNA encapsidation. • Protein IX exhibits a unique conformation of trimeric coiled–coiled structure. • Cleavage of precursor protein VI occurs during the DNA encapsidation process

  15. Intermediate Filaments at the Junction of Mechanotransduction, Migration, and Development

    Directory of Open Access Journals (Sweden)

    Rucha Sanghvi-Shah

    2017-09-01

    Full Text Available Mechanically induced signal transduction has an essential role in development. Cells actively transduce and respond to mechanical signals and their internal architecture must manage the associated forces while also being dynamically responsive. With unique assembly-disassembly dynamics and physical properties, cytoplasmic intermediate filaments play an important role in regulating cell shape and mechanical integrity. While this function has been recognized and appreciated for more than 30 years, continually emerging data also demonstrate important roles of intermediate filaments in cell signal transduction. In this review, with a particular focus on keratins and vimentin, the relationship between the physical state of intermediate filaments and their role in mechanotransduction signaling is illustrated through a survey of current literature. Association with adhesion receptors such as cadherins and integrins provides a critical interface through which intermediate filaments are exposed to forces from a cell's environment. As a consequence, these cytoskeletal networks are posttranslationally modified, remodeled and reorganized with direct impacts on local signal transduction events and cell migratory behaviors important to development. We propose that intermediate filaments provide an opportune platform for cells to both cope with mechanical forces and modulate signal transduction.

  16. Cryo-EM structures of two bovine adenovirus type 3 intermediates

    Energy Technology Data Exchange (ETDEWEB)

    Cheng, Lingpeng; Huang, Xiaoxing; Li, Xiaomin [National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101 (China); Xiong, Wei [State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Luo-jia-shan, Wuhan, Hubei 430072 (China); Sun, Wei; Yang, Chongwen; Zhang, Kai; Wang, Ying [National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101 (China); Liu, Hongrong [College of Physics and Information Science, Hunan Normal University, Changsha, Hunan 410081 (China); Huang, Xiaojun; Ji, Gang; Sun, Fei [National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101 (China); Zheng, Congyi, E-mail: cctcc202@whu.edu.cn [State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Luo-jia-shan, Wuhan, Hubei 430072 (China); Zhu, Ping, E-mail: zhup@ibp.ac.cn [National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101 (China)

    2014-02-15

    Adenoviruses (Ads) infect hosts from all vertebrate species and have been investigated as vaccine vectors. We report here near-atomic structures of two bovine Ad type 3 (BAd3) intermediates obtained by cryo-electron microscopy. A comparison between the two intermediate structures reveals that the differences are localized in the fivefold vertex region, while their facet structures are identical. The overall facet structure of BAd3 exhibits a similar structure to human Ads; however, BAd3 protein IX has a unique conformation. Mass spectrometry and cryo-electron tomography analyses indicate that one intermediate structure represents the stage during DNA encapsidation, whilst the other intermediate structure represents a later stage. These results also suggest that cleavage of precursor protein VI occurs during, rather than after, the DNA encapsidation process. Overall, our results provide insights into the mechanism of Ad assembly, and allow the first structural comparison between human and nonhuman Ads at backbone level. - Highlights: • First structure of bovine adenovirus type 3. • Some channels are located at the vertex of intermediate during DNA encapsidation. • Protein IX exhibits a unique conformation of trimeric coiled–coiled structure. • Cleavage of precursor protein VI occurs during the DNA encapsidation process.

  17. Singlet channel coupling in deuteron elastic scattering at intermediate energies

    International Nuclear Information System (INIS)

    Al-Khalili, J.S.; Tostevin, J.A.; Johnson, R.C.

    1990-01-01

    Intermediate energy deuteron elastic scattering is investigated in a three-body model incorporating relativistic kinematics. The effects of deuteron breakup to singlet spin intermediate states, on the elastic scattering observables for the 58 Ni(d vector, d) 58 Ni reaction at 400 and 700 MeV, are studied quantitatively. The singlet-breakup contributions to the elastic amplitude are estimated within an approximate two-step calculation. The calculation makes an adiabatic approximation in the intermediate states propagator which allows the use of closure over the np intermediate states continuum. The singlet channel coupling is found to produce large effects on the calculated reaction tensor analysing power A yy , characteristic of a dynamically induced second-rank tensor interaction. By inspection of the calculated breakup amplitudes we show this induced interaction to be of the T L tensor type. (orig.)

  18. Oxidative degradation of atenolol by heat-activated persulfate: Kinetics, degradation pathways and distribution of transformation intermediates.

    Science.gov (United States)

    Miao, Dong; Peng, Jianbiao; Zhou, Xiaohuan; Qian, Li; Wang, Mengjie; Zhai, Li; Gao, Shixiang

    2018-05-17

    Atenolol (ATL) has been widely detected in wastewater and aquatic environment. Although satisfactory removal of ATL from wastewater could be achieved, the mineralization ratio is usually low, which may result in the accumulation of its transformation products in the effluent and cause additional ecological risk to the environment. The aim of this study is to explore the effectiveness of heat activated persulfate (PS) in the removal of ATL from wastewater. Influencing factors including temperature, PS dosage, solution pH, existence of NO 3 - , Cl - , HCO 3 - and Suwannee river fulvic acid (SRFA) were examined. Complete removal of ATL was achieved within 40 min at pH 7.0 and 70 °C by using 0.5 mM PS. Inhibitive effects of HCO 3 - and FA had been observed on ATL oxidation, which was increased with the increase of their concentration. Sulfate radical (SO 4 - ) was determined as the main reactive species by quenching experiment. Eight intermediates produced in ATL degradation were identified, and four degradation pathways were proposed based on the analysis of mass spectrum and frontier electron densities. The distribution of major intermediates was influenced by reaction temperature. Hydroxylation intermediates and deamidation intermediate were the most prominent at 50 °C and 60 °C, respectively. All intermediates were completely degraded in 40 min except P134 at 70 °C. Effective removal of TOC (74.12%) was achieved with 0.5 mM PS, pH 7.0 and 70 °C after 240 min. The results proved that heat activation of PS is a promising method to remove organic pollutants in wastewater. Copyright © 2018 Elsevier Ltd. All rights reserved.

  19. Outcomes and toxicities in patients with intermediate-risk prostate cancer treated with brachytherapy alone or brachytherapy and supplemental external beam radiation therapy.

    Science.gov (United States)

    Schlussel Markovic, Emily; Buckstein, Michael; Stone, Nelson N; Stock, Richard G

    2018-05-01

    To evaluate the cancer control outcomes and long-term treatment-related morbidity of brachytherapy as well as combination brachytherapy and external beam radiation therapy (EBRT) in patients with intermediate-risk prostate cancer. A retrospective review was conducted in a prospectively collected database of patients with intermediate-risk prostate cancer who were treated either with brachytherapy or brachytherapy and EBRT, with or without androgen deprivation therapy (ADT), in the period 1990-2014. Urinary and erectile dysfunction symptoms were measured using the International Prostate Symptom Score (IPSS), the Mount Sinai erectile function scale and the Sexual Health Inventory for Men (SHIM). Cancer control endpoints included biochemical failure and development of distant metastases. All statistical analyses were carried out using the Statistical Package for Social Science (SPSS). Survival curves were calculated using Kaplan-Meier actuarial methods and compared using log-rank tests. Cox regression multivariate analyses were used to test the effect of multiple variables on treatment outcomes. A total of 902 patients were identified, with a median follow-up of 91 months. Of these, 390 received brachytherapy and 512 received combination therapy with EBRT. In patients with one intermediate-risk factor, the addition of EBRT did not significantly affect freedom from biochemical failure or distant metastases. Among patients with two or three intermediate-risk factors, added EBRT did not improve freedom from biochemical failure. Significant differences in late toxicity between patients treated with brachytherapy vs combination brachytherapy and EBRT were identified including urge incontinence (P actuarial methods showed that patients receiving combination therapy more frequently experienced loss of potency, as measured by the Mount Sinai erectile function scale (P = 0.040). Brachytherapy monotherapy results in equal biochemical and distant control in both patients with

  20. Stakeholder Support for School Food Policy Expansions

    Science.gov (United States)

    Pettigrew, Simone; Pescud, Melanie; Donovan, Robert J.

    2012-01-01

    The aim of this study was to assess the extent to which parents and school-based stakeholders (principals, teachers, canteen managers and Parents & Citizen Committee presidents) are supportive of potential expansions to a new school food policy. Eight additional policy components elicited in preliminary focus groups with parents and 19 additional…

  1. "Affective Encounters": Live Intermedial Spaces in Sites of Trauma

    Science.gov (United States)

    Scott, Jo

    2016-01-01

    This article addresses live intermediality as a tool for creative learning in the context of workshops carried out with young people in the town of Terezin, in the Czech Republic, site of the Nazi concentration camp, Theresienstadt. Live intermediality, as a mode of live media practice, involves the real time mixing and merging of sound, image,…

  2. Control of Groundwater Pollution from Animal Feeding Operations: A Farm-Level Dynamic Model for Policy Analysis

    Science.gov (United States)

    Wang, J.; Baerenklau, K.

    2012-12-01

    , policies targeting intermediate pollution and final pollution create incentives for the operator to examine the effects of other management practices to reduce pollution in addition to controlling the polluting inputs. Incentive-based mechanisms are slightly more cost-effective than quantity controls when seasonal emissions fluctuate. Our approach demonstrates the importance of taking into account the spatial & temporal dynamics in the rootzone and the integrated effects of water, nitrogen, and salinity on crop yield and nitrate emissions. It also highlights the significant role the environment can play in pollution control and the potential benefits from designing policies that acknowledge this role.oss of Total Net Farm Income Under Alternative Policies

  3. An analysis of system pressure and temperature distribution in self-pressurizer of SMART considering thermal stratification at intermediate cavity

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Yeon Moon; Lee, Doo Jeong; Yoon, Ju Hyun; Kim, Hwan Yeol [Korea Atomic Energy Research Institute, Taejon (Korea)

    1999-03-01

    Because the pressurizer is in reactor vessel, the heat transfer from primary water would increase the temperatures of fluids in pressurizer to same temperature of hotleg, if no cooling equipment were supplied. Thus, heat exchanger and thermal insulator are needed to minimize heat transferred from primary water and to remove heat in pressurizer. The temperatures in cavities of pressurizer for normal operation are 70 deg C and 74 deg C for intermediate and end cavity, respectively, which considers the solubility of nitrogen gas in water. Natural convection is the mechanism of heat balance in pressurizer of SMART. In SMART, the heat exchanger in pressurizer is placed in lower part of intermediate cavity, so the heat in upper part of intermediate cavity can't be removed adequately and it can cause thermal stratification. If thermal stratification occurred, it increases heat transfers to nitrogen gas and system pressure increases as the result. Thus, proper evaluation of those effects on system pressure and ways to mitigate thermal stratification should be established. This report estimates the system pressure and temperatures in cavities of pressurizer with considering thermal stratification in intermediate cavity. The system pressure and temperatures for each cavities considered size of wet thermal insulator, temperature of upper plate of reactor vessel, parameters of heat exchanger in intermediate cavity such as flow rate and temperature of cooling water, heat transfer area, effective tube height, and location of cooling tube. In addition to the consideration of thermal stratification thermal mixing of all water in intermediate cavity also considered and compared in this report. (author). 6 refs., 60 figs., 2 tabs.

  4. Oxidative demethylation of lanosterol in cholesterol biosynthesis: accumulation of sterol intermediates

    International Nuclear Information System (INIS)

    Shafiee, A.; Trzaskos, J.M.; Paik, Y.K.; Gaylor, J.L.

    1986-01-01

    With [ 3 H-24,25]-dihydrolanosterol as substrate, large-scale metabolic formation of intermediates of lanosterol demethylation was carried out to identify all compounds in the metabolic process. Utilizing knowledge of electron transport of lanosterol demethylation, we interrupted the demethylation reaction allowing accumulation and confirmation of the structure of the oxygenated intermediates lanost-8-en-3 beta,32-diol and 3 beta-hydroxylanost-8-en-32-al, as well as the demethylation product 4,4-dimethyl-cholesta-8,14-dien-3 beta-ol. Further metabolism of the delta 8.14-diene intermediate to a single product 4,4-dimethyl-cholest-8-en-3 beta-ol occurs under interruption conditions in the presence of 0.5 mM CN-1. With authentic compounds, each intermediate has been rigorously characterized by high performance liquid chromatography and gas-liquid chromatography plus mass spectral analysis of isolated and derivatized sterols. Intermediates that accumulated in greater abundance were further characterized by ultraviolet, 1 H-NMR, and infrared spectroscopy of the isolated sterols

  5. About the investigation of the ultrasonic absorption in intermediate states of superconductors

    International Nuclear Information System (INIS)

    Shepelev, A.G.

    2003-01-01

    Investigation of intermediate state in the bulk of superconductors are surveyed. Consideration is given to a previous attempt of eliminating edge effects in the ultrasonic investigation of intermediate states of pure gallium and molybdenum;it is demonstrated that those results are in strong contradiction with Landau's intermediate-state theory

  6. Identification of combustion intermediates in low-pressure premixed pyridine/oxygen/argon flames.

    Science.gov (United States)

    Tian, Zhenyu; Li, Yuyang; Zhang, Taichang; Zhu, Aiguo; Qi, Fei

    2008-12-25

    Combustion intermediates of two low-pressure premixed pyridine/oxygen flames with respective equivalence ratios of 0.56 (C/O/N = 1:4.83:0.20) and 2.10 (C/O/N = 1:1.29:0.20) have been identified with tunable synchrotron vacuum ultraviolet (VUV) photoionization and molecular-beam mass spectrometry techniques. About 80 intermediates in the rich flame and 60 intermediates in the lean flame, including nitrogenous, oxygenated, and hydrocarbon intermediates, have been identified by measurements of photoionization mass spectra and photoionization efficiency spectra. Some radicals and new nitrogenous intermediates are identified in the present work. The experimental results are useful for studying the conversion of volatile nitrogen compounds and understanding the formation mechanism of NO(x) in flames of nitrogenous fuels.

  7. Photodissociation dynamics and spectroscopy of free radical combustion intermediates

    Energy Technology Data Exchange (ETDEWEB)

    Osborn, David Lewis [Univ. of California, Berkeley, CA (United States)

    1996-12-01

    The photodissociation spectroscopy and dynamics of free radicals is studied by the technique of fast beam photofragment translational spectroscopy. Photodetachment of internally cold, mass-selected negative ions produces a clean source of radicals, which are subsequently dissociated and detected. The photofragment yield as a function of photon energy is obtained, mapping out the dissociative and predissociative electronic states of the radical. In addition, the photodissociation dynamics, product branching ratios, and bond energies are probed at fixed photon energies by measuring the translational energy, P(ET), and angular distribution of the recoiling fragments using a time- and position-sensitive detector. Ab initio calculations are combined with dynamical and statistical models to interpret the observed data. The photodissociation of three prototypical hydrocarbon combustion intermediates forms the core of this work.

  8. A Concept Analysis of Patient Participation in Intermediate Care.

    Science.gov (United States)

    Kvæl, Linda Aimée Hartford; Debesay, Jonas; Langaas, Anne; Bye, Asta; Bergland, Astrid

    2018-03-05

    Although the concept of patient participation has been discussed for a number of years, there is still no clear definition of what constitutes the multidimensional concept, and the application of the concept in an intermediate care (IC) context lacks clarity. Therefore this paper seeks to identify and explore the attributes of the concept, to elaborate ways of understanding the concept of patient participation for geriatric patients in the context of IC. Walker and Avant's model of Concept analysis [1] based on a literature review. Patient participation in the context of IC can be defined as a dynamic process emphasizing the person as a whole, focusing on the establishment of multiple alliances that facilitate individualized information and knowledge exchange, and ensuring a reciprocal engagement in activities within flexible and interactive/dynamic organizational structures. Patient participation in IC means involving patients and their relatives in holistic interdisciplinary collaborative decision-making. The results highlight the complexity of patient participation and contribute to a greater understanding of the influence of organizational structure and management. The present study may provide a practical framework for researchers, policy makers and health professionals to facilitate patient participation in IC services. Copyright © 2018 Elsevier B.V. All rights reserved.

  9. Whereas Short-Term Facilitation Is Presynaptic, Intermediate-Term Facilitation Involves Both Presynaptic and Postsynaptic Protein Kinases and Protein Synthesis

    Science.gov (United States)

    Jin, Iksung; Kandel, Eric R.; Hawkins, Robert D.

    2011-01-01

    Whereas short-term plasticity involves covalent modifications that are generally restricted to either presynaptic or postsynaptic structures, long-term plasticity involves the growth of new synapses, which by its nature involves both pre- and postsynaptic alterations. In addition, an intermediate-term stage of plasticity has been identified that…

  10. Beyond policy networks: policy framing and the politics of expertise in the 2001 Foot and Mouth Disease crisis.

    Science.gov (United States)

    Wilkinson, Katy; Lowe, Philip; Donaldson, Andrew

    2010-01-01

    For the past decade, the policy community/issue network typology of pressure group interaction has been used to explain policy outcomes and the policy-making process. To re-examine the validity of this typology, the paper focuses on the UK government's response to the 2001 Foot and Mouth Disease (FMD) crisis, and in particular the decision to pursue contiguous culling rather than vaccination to overcome the epidemic. Rather than illustrating the emergence of an issue network in agricultural policy, the decision-making process of the FMD outbreak demonstrates continuity with prior crises. In addition, the politicization of scientific expertise is identified as an emerging trend in crisis management. Policy framing is used to explain the impetus behind the contiguous cull decision, concluding that the legacy of previous policy choices conditioned the crisis response to a far greater degree than contemporaneous pressure group action.

  11. Exome sequencing identifies CTSK mutations in patients originally diagnosed as intermediate osteopetrosis☆

    Science.gov (United States)

    Pangrazio, Alessandra; Puddu, Alessandro; Oppo, Manuela; Valentini, Maria; Zammataro, Luca; Vellodi, Ashok; Gener, Blanca; Llano-Rivas, Isabel; Raza, Jamal; Atta, Irum; Vezzoni, Paolo; Superti-Furga, Andrea; Villa, Anna; Sobacchi, Cristina

    2014-01-01

    Autosomal Recessive Osteopetrosis is a genetic disorder characterized by increased bone density due to lack of resorption by the osteoclasts. Genetic studies have widely unraveled the molecular basis of the most severe forms, while cases of intermediate severity are more difficult to characterize, probably because of a large heterogeneity. Here, we describe the use of exome sequencing in the molecular diagnosis of 2 siblings initially thought to be affected by “intermediate osteopetrosis”, which identified a homozygous mutation in the CTSK gene. Prompted by this finding, we tested by Sanger sequencing 25 additional patients addressed to us for recessive osteopetrosis and found CTSK mutations in 4 of them. In retrospect, their clinical and radiographic features were found to be compatible with, but not typical for, Pycnodysostosis. We sought to identify modifier genes that might have played a role in the clinical manifestation of the disease in these patients, but our results were not informative. In conclusion, we underline the difficulties of differential diagnosis in some patients whose clinical appearance does not fit the classical malignant or benign picture and recommend that CTSK gene be included in the molecular diagnosis of high bone density conditions. PMID:24269275

  12. The quest for an intermediate-scale accidental axion and further ALPs

    International Nuclear Information System (INIS)

    Dias, A.G.; Nishi, C.C.; Machado, A.C.B.; Vaudrevange, P.

    2014-03-01

    The recent detection of the cosmic microwave background polarimeter experiment BICEP2 of tensor fluctuations in the B-mode power spectrum basically excludes all plausible axion models where its decay constant is above 10 13 GeV. Moreover, there are strong theoretical, astrophysical, and cosmological motivations for models involving, in addition to the axion, also axion-like particles (ALPs), with decay constants in the intermediate scale range, between 10 9 GeV and 10 13 GeV. Here, we present a general analysis of models with an axion and further ALPs and derive bounds on the relative size of the axion and ALP photon (and electron) coupling. We discuss what we can learn from measurements of the axion and ALP photon couplings about the fundamental parameters of the underlying ultraviolet completion of the theory. For the latter we consider extensions of the Standard Model in which the axion and the ALP(s) appear as pseudo Nambu-Goldstone bosons from the breaking of global chiral U(1) (Peccei-Quinn (PQ)) symmetries, occuring accidentally as low energy remnants from exact discrete symmetries. In such models, the axion and the further ALP are protected from disastrous explicit symmetry breaking effects due to Planck-scale suppressed operators. The scenarios considered exploit heavy right handed neutrinos getting their mass via PQ symmetry breaking and thus explain the small mass of the active neutrinos via a seesaw relation between the electroweak and an intermediate PQ symmetry breaking scale. We show some models that can accommodate simultaneously an axion dark matter candidate, an ALP explaining the anomalous transparency of the universe for γ-rays, and an ALP explaining the recently reported 3.55 keV gamma line from galaxies and clusters of galaxies, if the respective decay constants are of intermediate scale.

  13. The quest for an intermediate-scale accidental axion and further ALPs

    Energy Technology Data Exchange (ETDEWEB)

    Dias, A.G.; Nishi, C.C. [Univ. Federal do ABC - UFABC, Sao Paulo (Brazil); Machado, A.C.B. [Teorica-Univ. Estadual Paulista, Sao Paulo (Brazil). Instituto de Fisica; Ringwald, A. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Vaudrevange, P. [Technische Univ. Muenchen, Garching (Germany). Excellence Cluster Universe

    2014-03-15

    The recent detection of the cosmic microwave background polarimeter experiment BICEP2 of tensor fluctuations in the B-mode power spectrum basically excludes all plausible axion models where its decay constant is above 10{sup 13} GeV. Moreover, there are strong theoretical, astrophysical, and cosmological motivations for models involving, in addition to the axion, also axion-like particles (ALPs), with decay constants in the intermediate scale range, between 10{sup 9} GeV and 10{sup 13} GeV. Here, we present a general analysis of models with an axion and further ALPs and derive bounds on the relative size of the axion and ALP photon (and electron) coupling. We discuss what we can learn from measurements of the axion and ALP photon couplings about the fundamental parameters of the underlying ultraviolet completion of the theory. For the latter we consider extensions of the Standard Model in which the axion and the ALP(s) appear as pseudo Nambu-Goldstone bosons from the breaking of global chiral U(1) (Peccei-Quinn (PQ)) symmetries, occuring accidentally as low energy remnants from exact discrete symmetries. In such models, the axion and the further ALP are protected from disastrous explicit symmetry breaking effects due to Planck-scale suppressed operators. The scenarios considered exploit heavy right handed neutrinos getting their mass via PQ symmetry breaking and thus explain the small mass of the active neutrinos via a seesaw relation between the electroweak and an intermediate PQ symmetry breaking scale. We show some models that can accommodate simultaneously an axion dark matter candidate, an ALP explaining the anomalous transparency of the universe for γ-rays, and an ALP explaining the recently reported 3.55 keV gamma line from galaxies and clusters of galaxies, if the respective decay constants are of intermediate scale.

  14. Impact of Lesion Length on Functional Significance in Intermediate Coronary Lesions

    Directory of Open Access Journals (Sweden)

    Morteza Safi

    2017-07-01

    Full Text Available Introduction: The present study aimed at assessing the role of lesion length in predicting Fractional Flow Reserve (FFR value for physiological evaluation of intermediate coronary lesions.Methods: In the current study, 68 patients with 83 coronary lesions were enrolled. All of the patients in this study underwent routine coronary angiography, according to appropriate indications. To evaluate physiologically significant intermediate coronary stenosis (defined between 40% and 70% on visual estimation, the Fractional Flow Reserve (FFR study was performed and the Quantitative Coronary Angiography (QCA data were also assessed for measurement of lesion length. The correlation between QCA data and FFR values was also examined.Results: Eighty-three lesions were evaluated from 68 patients. Stenosis was considered physiologically significant when FFR was lower than 0.75. The FFR was significant in twelve lesions (14.5%. There was a negative correlation between FFR value and lesion length (r = -0.294 and P = 0.013. Moreover, lesion length in physiologically significant FFR group (21.07  ± 6.9 was greater than that of the non-significant FFR group (15.23 ± 6.5 (P value < 0.05. Furthermore, the correlation between QCA data and FFR values was also investigated, yet, there was only a positive correlation between FFR and Minimum Luminal Diameter (MLD values (r = 0.248 and P value = 0.04. The Receiver Operating Characteristic (ROC curve analysis for predicting the significant FFR value demonstrated that a lesion length greater than 17.5 mm was the best cut-off point for prediction of the significant FFR value with acceptable sensitivity and specificity of 83.3% and 68.8%, respectively.Conclusions: There is a negative correlation between lesion length and FFR value in intermediate coronary lesions. In addition, a lesion length greater than 17.5 mm is the best cut- off point for prediction of significant FFR values.

  15. Hγ Line Spectrum of Intermediate Polars

    Directory of Open Access Journals (Sweden)

    Yonggi Kim

    1998-06-01

    Full Text Available Kim & Beuermann (1995, 1996 have developed a model for the propagation of X-rays from the accreting white dwarf through the infalling material and the re-emission of the energy deposited by photo-absorption in the optical (and UV spectral range. By using this model, we calculate the profiles of the Hγ emission-line spectrum of intermediate polars. Photoabsorption of X-rays by the infalling material is the dominant process in forming the observed energy-dependent rotational modulation of the X-ray flux. X-ray and optical modulations are sensitive to model parameters in different ways. In principle, these dependencies allow us to obtain improved insight into the accretion geometry of the intermediate polars. We present results of our calculations and compare them with the Hβ line spectrum (Kim & Beuermann 1996.

  16. Intermediate pond sizes contain the highest density, richness, and diversity of pond-breeding amphibians.

    Directory of Open Access Journals (Sweden)

    Raymond D Semlitsch

    Full Text Available We present data on amphibian density, species richness, and diversity from a 7140-ha area consisting of 200 ponds in the Midwestern U.S. that represents most of the possible lentic aquatic breeding habitats common in this region. Our study includes all possible breeding sites with natural and anthropogenic disturbance processes that can be missing from studies where sampling intensity is low, sample area is small, or partial disturbance gradients are sampled. We tested whether pond area was a significant predictor of density, species richness, and diversity of amphibians and if values peaked at intermediate pond areas. We found that in all cases a quadratic model fit our data significantly better than a linear model. Because small ponds have a high probability of pond drying and large ponds have a high probability of fish colonization and accumulation of invertebrate predators, drying and predation may be two mechanisms driving the peak of density and diversity towards intermediate values of pond size. We also found that not all intermediate sized ponds produced many larvae; in fact, some had low amphibian density, richness, and diversity. Further analyses of the subset of ponds represented in the peak of the area distribution showed that fish, hydroperiod, invertebrate density, and canopy are additional factors that drive density, richness and diversity of ponds up or down, when extremely small or large ponds are eliminated. Our results indicate that fishless ponds at intermediate sizes are more diverse, produce more larvae, and have greater potential to recruit juveniles into adult populations of most species sampled. Further, hylid and chorus frogs are found predictably more often in ephemeral ponds whereas bullfrogs, green frogs, and cricket frogs are found most often in permanent ponds with fish. Our data increase understanding of what factors structure and maintain amphibian diversity across large landscapes.

  17. Nuclear spin-orbit splitting from an intermediate Δ excitation

    International Nuclear Information System (INIS)

    Ohta, K.; Terasawa, T.; Tohyama, M.

    1980-01-01

    The strength of the single particle spin-orbit potential is calculated from the two pion exchange box diagrams involving an intermediate Δ(1232) resonance excitation by taking account of the exclusion principle for the intermediate nucleon states. The effect of the rho meson is also considered. The predicted strength is found to account for a substantial part of the empirical spin-orbit splittings

  18. Development of National Technology Audit Policy

    Directory of Open Access Journals (Sweden)

    Subiyanto Subiyanto

    2017-07-01

    Full Text Available The Laws have mandated implementation of technology audit, nevertheless such implementation needs an additional policy that is more technical. The concept of national audit technology policy shall make technology audit as a tool to ensure the benefit of technology application for society and technology advance for nation independency. This article discusses on technology audit policy concept especially infrastructure requirement, with emphasis on regulation, implementation tools, and related institution. The development of technology audit policy for national interest requires provision of mandatory audit implementation, accompanied by tools for developing technology auditor’s competence and technology audit institutional’s mechanism. To guide technology auditor’s competence, concept of national audit technology policy shall classify object of technology audit into product technology, production technology, and management of technology, accompanied by related parameters of technology performance evaluation.

  19. Enhancement of intermediate-field two-photon absorption by rationally shaped femtosecond pulses

    International Nuclear Information System (INIS)

    Chuntonov, Lev; Rybak, Leonid; Gandman, Andrey; Amitay, Zohar

    2008-01-01

    We extend the powerful frequency-domain analysis of femtosecond two-photon absorption to the intermediate-field regime of considerable absorption yields, where additionally to the weak-field nonresonant two-photon transitions also four-photon transitions play a role. Consequently, we rationally find that the absorption is enhanced over the transform-limited pulse by any shaped pulse having a spectral phase that is antisymmetric around one-half of the transition frequency and a spectrum that is asymmetric around it (red or blue detuned according to the system). The enhancement increases as the field strength increases. The theoretical results for Na are verified experimentally

  20. 42 CFR 422.750 - Types of intermediate sanctions and civil money penalties.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Types of intermediate sanctions and civil money... § 422.750 Types of intermediate sanctions and civil money penalties. (a) The following intermediate... organization. (b) CMS may impose civil money penalties as specified in 422.760. [72 FR 68725, Dec. 5, 2007, as...

  1. Microdosimetry of intermediate energy neutrons in fast neutron fields

    International Nuclear Information System (INIS)

    Saion, E.B.; Watt, D.E.

    1988-01-01

    A coaxial double cylindrical proportional counter has been constructed for microdosimetry of intermediate energy neutrons in mixed fields. Details are given of the measured gas gain and resolution characteristics of the counter for a wide range of anode voltages. Event spectra due to intermediate neutrons in any desired energy band is achieved by an appropriate choice of thickness of the common dividing wall in the counter and by appropriate use of the coincidence, anticoincidence pulse counting arrangements. Calculated estimates indicate that the dose contribution by fast neutrons to the energy deposition events in the intermediate neutron range may be as large as 25%. Empirical procedures being investigated aim to determine the necessary corrections to be applied to the microdose distributions, with a precision of 10%. (author)

  2. About the structure of quantum intermediate state of superconductors

    International Nuclear Information System (INIS)

    Ledenev, O.P.

    2008-01-01

    The calculation of spatial structure of a quantum intermediate state in Type I superconductors is completed. Theoretical model of thermodynamics of considered state was proposed by Andreev. It is shown, that in a quantum case, the period of structure appears significantly smaller and has different dependence on both the magnetic field and temperature than in the classical intermediate Landau state. The decrease of thickness of normal layers results in increase of characteristic distance between the quantum Andreev levels of electronic excitations, and the transition to the quantum intermediate from classical state is realized at higher temperatures ∼1 K, than it was supposed in previous works. The comparison of calculation data with experimental results, for example using the sample of mono-crystal gallium, is conducted

  3. Deep and intermediate mediterranean water in the western Alboran Sea

    Science.gov (United States)

    Parrilla, Gregorio; Kinder, Thomas H.; Preller, Ruth H.

    1986-01-01

    Hydrographic and current meter data, obtained during June to October 1982, and numerical model experiments are used to study the distribution and flow of Mediterranean waters in the western Alboran Sea. The Intermediate Water is more pronounced in the northern three-fourths of the sea, but its distribution is patchy as manifested by variability of the temperature and salinity maxima at scales ≤10 km. Current meters in the lower Intermediate Water showed mean flow toward the Strait at 2 cm s -1. A reversal of this flow lasted about 2 weeks. A rough estimate of the mean westward Intermediate Water transport was 0.4 × 10 6 m 3 s -1, about one-third of the total outflow, so that the best estimates of the contributions of traditionally defined Intermediate Water and Deep Water account for only about one-half of the total outflow. The Deep Water was uplifted against the southern continental slope from Alboran Island (3°W) to the Strait. There was also a similar but much weaker banking against the Spanish slope, but a deep current record showed that the eastward recirculation implied by this banking is probably intermittent. Two-layer numerical model experiments simulated the Intermediate Water flow with a flat bottom and the Deep Water with realistic bottom topography. Both experiments replicated the major circulation features, and the Intermediate Water flow was concentrated in the north because of rotation and the Deep Water flow in the south because of topographic control.

  4. The relationship between sun protection policies and practices in schools with primary-age students: the role of school demographics, policy comprehensiveness and SunSmart membership.

    Science.gov (United States)

    Dono, J; Ettridge, K A; Sharplin, G R; Wilson, C J

    2014-02-01

    Schools can implement evidence-based sun protection policies that guide practices to help protect children from harmful sun exposure. This national study assessed the relationship between the existence and comprehensiveness of written policies and the comprehensiveness of sun protection practices. The impact of school demographics on the strength of the relationship was also examined, as was the possibility that 'SunSmart' membership would have an additional impact on practices, beyond having any formal policy. In 2011-12, staff members of 1573 schools catering to primary-age students completed a self-administered survey about sun protection policies and practices (response rate of 57%). Results showed that schools with a written policy had more comprehensive practices than schools without a written policy. The relationship between having a written policy and sun protection practices was stronger for remote schools compared with metropolitan and regional schools, and for schools catering to both primary and secondary students compared with primary students only. In addition, policy comprehensiveness was associated with practice comprehensiveness, and SunSmart membership was indirectly related to practice comprehensiveness via policy comprehensiveness. These results indicate that written policies relate to practice comprehensiveness, but the strength of the association can vary according to the characteristics of the organization.

  5. A hybrid intermediate language between SSA and CPS

    DEFF Research Database (Denmark)

    Torrens, Paulo; Vasconcellos, Cristiano; Gonçalves, Ju

    2017-01-01

    passing style (CPS) lambda calculus has been used as intermediate language for functional language compilers, they are (almost) equivalent and it is possible to draw syntactic translations between them. This short paper aims to present an untyped intermediate language which may be interpreted as both SSA...... and CPS, in order to provide a common language for both imperative and functional compilers, as well to take advantage of optimizations designed for either one of the approaches. Finally, potential variants and research opportunities are discussed....

  6. Intermediate states in quantum cryptography and Bell inequalities

    International Nuclear Information System (INIS)

    Bechmann-Pasquinucci, H.; Gisin, N.

    2003-01-01

    Intermediate states are known from intercept/resend eavesdropping in the Bennett-Brassard 1984 (BB84) quantum cryptographic protocol. But they also play fundamental roles in the optimal eavesdropping strategy on the BB84 protocol and in the CHSH (Clauser-Horne-Shimony-Holt) inequality. We generalize the intermediate states to an arbitrary dimension and consider intercept/resend eavesdropping, optimal eavesdropping on the generalized BB84 protocol and present a generalized Clauser-Horne-Shimony-Holt inequality for two entangled qudits based on these states

  7. Reactivity of Criegee Intermediates toward Carbon Dioxide.

    Science.gov (United States)

    Lin, Yen-Hsiu; Takahashi, Kaito; Lin, Jim Jr-Min

    2018-01-04

    Recent theoretical work by Kumar and Francisco suggested that the high reactivity of Criegee intermediates (CIs) could be utilized for designing efficient carbon capture technologies. Because the anti-CH 3 CHOO + CO 2 reaction has the lowest barrier in their study, we chose to investigate it experimentally. We probed anti-CH 3 CHOO with its strong UV absorption at 365 nm and measured the rate coefficient to be ≤2 × 10 -17 cm 3 molecule -1 s -1 at 298 K, which is consistent with our theoretical value of 2.1 × 10 -17 cm 3  molecule -1 s -1 at the QCISD(T)/CBS//B3LYP/6-311+G(2d,2p) level but inconsistent with their results obtained at the M06-2X/aug-cc-pVTZ level, which tends to underestimate the barrier heights. The experimental result indicates that the reaction of a Criegee intermediate with atmospheric CO 2 (400 ppmv) would be inefficient (k eff < 0.2 s -1 ) and cannot compete with other decay processes of Criegee intermediates like reactions with water vapor (∼10 3 s -1 ) or thermal decomposition (∼10 2 s -1 ).

  8. Intermediate-range order in lead metasilicate glass

    Energy Technology Data Exchange (ETDEWEB)

    Suzuya, Kentaro [Japan Atomic Energy Research Inst., Ako, Hyogo (Japan)]|[Argonne National Lab., IL (United States). Materials Science Div.; Price, D.L.; Saboungi, M.L. [Argonne National Lab., IL (United States). Materials Science Div.; Ohno, Hideo [Japan Atomic Energy Research Inst., Ako, Hyogo (Japan)

    1997-03-01

    The complementarity of anomalous X-ray scattering (AXS) and neutron diffraction (ND) techniques is used here to investigate the nature and origin of intermediate-range order in lead metasilicate glass. Both X-ray and neutron source factors reveal small peaks at low wave vector which are shown to be associated with intermediate-range order of the Pb-O network. The combination of AXS and ND is shown to be a powerful tool to correlate contributions from the different atom pairs to such a peak. The information thus derived is compared with results from alkali germanate glasses and with structural data on corresponding crystalline compounds.

  9. Low temperature intermediate band metallic behavior in Ti implanted Si

    Energy Technology Data Exchange (ETDEWEB)

    Olea, Javier, E-mail: oleaariza@fis.ucm.es; Pastor, David; Garcia-Hemme, Eric; Garcia-Hernansanz, Rodrigo; Prado, Alvaro del; Martil, Ignacio; Gonzalez-Diaz, German

    2012-08-31

    Si samples implanted with very high Ti doses and subjected to Pulsed-Laser Melting (PLM) have been electrically analyzed in the scope of a two-layer model previously reported based on the Intermediate Band (IB) theory. Conductivity and Hall effect measurements using the van der Pauw technique suggest that the insulator-metal transition takes place for implantation doses in the 10{sup 14}-10{sup 16} cm{sup -2} range. Results of the sample implanted with the 10{sup 16} cm{sup -2} dose show a metallic behavior at low temperature that is explained by the formation of a p-type IB out of the Ti deep levels. This suggests that the IB would be semi-filled, which is essential for IB photovoltaic devices. - Highlights: Black-Right-Pointing-Pointer We fabricated high dose Ti implanted Si samples for intermediate band research. Black-Right-Pointing-Pointer We measured the electronic transport properties in the 7-300 K range. Black-Right-Pointing-Pointer We show an insulator to metallic transition when the intermediate band is formed. Black-Right-Pointing-Pointer The intermediate band is semi-filled and populated by holes. Black-Right-Pointing-Pointer We satisfactorily explain the electrical behavior by an intermediate band model.

  10. Intermediate organizations in the innovation process in Mexico

    Directory of Open Access Journals (Sweden)

    Maria del Pilar Monserrat Pérez Hernández

    2016-07-01

    Full Text Available The innovation activity depends strongly on the interaction between generating actors and end-users of new knowledge and technologies. There are several intermediate organizations (IO that facilitate translating the needs of the users with the new technologies that are beingdeveloped, in order to satisfy more effectively their demands. This paper analyzes the mediation process involved in the IO in innovative activity in Mexico, to identify structural holes in the innovation process. The relevant results in the Mexican intermediation process points that threeimportant structural holes of the process are missing: one between the negotiation process and sponsorship, the second in marketing and commercial profit of the obtained results and the last one in the regulation and referring activities. It is very important that the detected missinglinks in the intermediation process are filled, because they can hinder considerably the overall profit and benefits that society could obtained of the innovation process.

  11. Public Opinion on Nutrition-Related Policies to Combat Child Obesity, Los Angeles County, 2011

    OpenAIRE

    Simon, Paul A.; Chiang, Choiyuk; Lightstone, Amy S.; Shih, Margaret

    2014-01-01

    We assessed public opinion on nutrition-related policies to address child obesity: a soda tax, restrictions on advertising unhealthy foods and beverages to children, and restrictions on siting fast food restaurants and convenience stores near schools. We analyzed data from 998 adults (aged ≥18 years) in the 2011 Los Angeles County Health Survey. Support was highest for advertising restrictions (74%), intermediate for a soda tax (60%), and lowest for siting restrictions on fast food restaurant...

  12. Policy Analysis on Growth and Employment - PAGE II | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Policy Analysis on Growth and Employment - PAGE II. This project by the Partnership for Economic Policy (PEP) will support quality ... The project is supported by the UK's Department for International Development, and additional funding is ...

  13. Monetary Transmission and Asset - Liability management by financial institutions in transitional economies - implications for czech monetary policy

    OpenAIRE

    Derviz, Alexis

    2000-01-01

    The paper deals with the transmission of monetary policy within the financial sector. The objective is to link an optimizing stochastic model of portfolio decisions by a representative financial institution with a number of features that this optimizing behavior implies for monetary transmission and credit conditions in a transitional economy. The main example is the intermediation performance of Czech financial sector in the years 1993 to 1999.

  14. The deterioration of intermediate moisture foods

    Science.gov (United States)

    Labruza, T. P.

    1971-01-01

    Deteriorative reactions are low and food quality high if intermediate moisture content of a food is held at a water activity of 0.6 to 0.75. Information is of interest to food processing and packaging industry.

  15. Production of intermediate-mass dileptons in relativistic heavy ion collisions

    International Nuclear Information System (INIS)

    Kvasnikova, Ioulia; Gale, Charles; Kumar Srivastava, Dinesh

    2002-01-01

    The production of intermediate-mass dileptons in ultrarelativistic nuclear collisions at SPS energies is studied. The acceptance and detector resolution inherent to measurements by the NA50 experimental collaboration are accurately modeled. The measured centrality dependence of the intermediate mass lepton pair excess is also addressed

  16. Intermediate uveitis

    Directory of Open Access Journals (Sweden)

    Babu B

    2010-01-01

    Full Text Available Intermediate uveitis (IU is described as inflammation in the anterior vitreous, ciliary body and the peripheral retina. In the Standardization of Uveitis Nomenclature (SUN working group′s international workshop for reporting clinical data the consensus reached was that the term IU should be used for that subset of uveitis where the vitreous is the major site of the inflammation and if there is an associated infection (for example, Lyme disease or systemic disease (for example, sarcoidosis. The diagnostic term pars planitis should be used only for that subset of IU where there is snow bank or snowball formation occurring in the absence of an associated infection or systemic disease (that is, "idiopathic". This article discusses the clinical features, etiology, pathogenesis, investigations and treatment of IU.

  17. RNA-Seq analysis uncovers non-coding small RNA system of Mycobacterium neoaurum in the metabolism of sterols to accumulate steroid intermediates.

    Science.gov (United States)

    Liu, Min; Zhu, Zhan-Tao; Tao, Xin-Yi; Wang, Feng-Qing; Wei, Dong-Zhi

    2016-04-25

    Understanding the metabolic mechanism of sterols to produce valuable steroid intermediates in mycobacterium by a noncoding small RNA (sRNA) view is still limited. In the work, RNA-seq was implemented to investigate the noncoding transcriptome of Mycobacterium neoaurum (Mn) in the transformation process of sterols to valuable steroid intermediates, including 9α-hydroxy-4-androstene-3,17-dione (9OHAD), 1,4-androstadiene-3,17-dione (ADD), and 22-hydroxy-23, 24-bisnorchola-1,4-dien-3-one (1,4-BNA). A total of 263 sRNA candidates were predicted from the intergenic regions in Mn. Differential expression of sRNA candidates was explored in the wide type Mn with vs without sterol addition, and the steroid intermediate producing Mn strains vs wide type Mn with sterol addition, respectively. Generally, sRNA candidates were differentially expressed in various strains, but there were still some shared candidates with outstandingly upregulated or downregulated expression in these steroid producing strains. Accordingly, four regulatory networks were constructed to reveal the direct and/or indirect interactions between sRNA candidates and their target genes in four groups, including wide type Mn with vs without sterol addition, 9OHAD, ADD, and BNA producing strains vs wide type Mn with sterol addition, respectively. Based on these constructed networks, several highly focused sRNA candidates were discovered to be prevalent in the networks, which showed comprehensive regulatory roles in various cellular processes, including lipid transport and metabolism, amino acid transport and metabolism, signal transduction, cell envelope biosynthesis and ATP synthesis. To explore the functional role of sRNA candidates in Mn cells, we manipulated the overexpression of candidates 131 and 138 in strain Mn-9OHAD, which led to enhanced production of 9OHAD from 1.5- to 2.3-fold during 6 d' fermentation and a slight effect on growth rate. This study revealed the complex and important regulatory

  18. File list: Unc.PSC.50.AllAg.iPSC_intermediates [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.PSC.50.AllAg.iPSC_intermediates mm9 Unclassified Pluripotent stem cell iPSC intermediates... http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/Unc.PSC.50.AllAg.iPSC_intermediates.bed ...

  19. File list: Pol.PSC.10.AllAg.iPSC_intermediates [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.PSC.10.AllAg.iPSC_intermediates mm9 RNA polymerase Pluripotent stem cell iPSC intermediates...e.biosciencedbc.jp/kyushu-u/mm9/assembled/Pol.PSC.10.AllAg.iPSC_intermediates.bed ...

  20. File list: Unc.PSC.20.AllAg.iPSC_intermediates [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.PSC.20.AllAg.iPSC_intermediates mm9 Unclassified Pluripotent stem cell iPSC intermediates... http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/Unc.PSC.20.AllAg.iPSC_intermediates.bed ...

  1. File list: Pol.PSC.05.AllAg.iPSC_intermediates [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.PSC.05.AllAg.iPSC_intermediates mm9 RNA polymerase Pluripotent stem cell iPSC intermediates...e.biosciencedbc.jp/kyushu-u/mm9/assembled/Pol.PSC.05.AllAg.iPSC_intermediates.bed ...

  2. File list: Pol.PSC.20.AllAg.iPSC_intermediates [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.PSC.20.AllAg.iPSC_intermediates mm9 RNA polymerase Pluripotent stem cell iPSC intermediates...e.biosciencedbc.jp/kyushu-u/mm9/assembled/Pol.PSC.20.AllAg.iPSC_intermediates.bed ...

  3. File list: Unc.PSC.10.AllAg.iPSC_intermediates [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.PSC.10.AllAg.iPSC_intermediates mm9 Unclassified Pluripotent stem cell iPSC intermediates... http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/Unc.PSC.10.AllAg.iPSC_intermediates.bed ...

  4. File list: Pol.PSC.50.AllAg.iPSC_intermediates [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.PSC.50.AllAg.iPSC_intermediates mm9 RNA polymerase Pluripotent stem cell iPSC intermediates...e.biosciencedbc.jp/kyushu-u/mm9/assembled/Pol.PSC.50.AllAg.iPSC_intermediates.bed ...

  5. File list: Unc.PSC.05.AllAg.iPSC_intermediates [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.PSC.05.AllAg.iPSC_intermediates mm9 Unclassified Pluripotent stem cell iPSC intermediates... http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/Unc.PSC.05.AllAg.iPSC_intermediates.bed ...

  6. The physics of long- and intermediate-wavelength asymmetries of the hot spot: Compression hydrodynamics and energetics

    International Nuclear Information System (INIS)

    Bose, A.; Betti, R.; Shvarts, D.; Woo, K. M.

    2017-01-01

    To achieve ignition with inertial confinement fusion (ICF), it is important to under- stand the effect of asymmetries on the hydrodynamics and energetics of the compres- sion. This paper describes a theoretical model for the compression of distorted hot spots, and quantitative estimates using hydrodynamic simulations. The asymmetries are categorized into low (Ι < 6) and intermediate (Ι < A < 40) modes by comparison of the wavelength with the thermal-diffusion scale length. Long-wavelength modes introduce substantial nonradial motion, whereas intermediate-wavelength modes in- volve more cooling by thermal ablation. We discover that for distorted hot spots, the measured neutron-averaged properties can be very different from the real hydro- dynamic conditions. This is because mass ablation driven my thermal conduction introduces flows in the Rayleigh–Taylor bubbles, this results in pressure variation, in addition to temperature variation between the bubbles and the neutron-producing region (~1 keV for intermediate modes). The differences are less pronounced for long-wavelength asymmetries since the bubbles are relatively hot and sustain fusion reactions. The yield degradation− with respect to the symmetric− results primarily from a reduction in the hot-spot pressure for low modes and from a reduction in burn volume for intermediate modes. It is shown that the degradation in internal energy of the hot-spot is equivalent for both categories, and is equal to the total residual energy in the shell including the bubbles. This quantity is correlated with the shell residual kinetic energy for low-modes, and includes the kinetic energy in the bubbles for mid-modes.

  7. Visual dictionaries as intermediate features in the human brain

    Directory of Open Access Journals (Sweden)

    Kandan eRamakrishnan

    2015-01-01

    Full Text Available The human visual system is assumed to transform low level visual features to object and scene representations via features of intermediate complexity. How the brain computationally represents intermediate features is still unclear. To further elucidate this, we compared the biologically plausible HMAX model and Bag of Words (BoW model from computer vision. Both these computational models use visual dictionaries, candidate features of intermediate complexity, to represent visual scenes, and the models have been proven effective in automatic object and scene recognition. These models however differ in the computation of visual dictionaries and pooling techniques. We investigated where in the brain and to what extent human fMRI responses to short video can be accounted for by multiple hierarchical levels of the HMAX and BoW models. Brain activity of 20 subjects obtained while viewing a short video clip was analyzed voxel-wise using a distance-based variation partitioning method. Results revealed that both HMAX and BoW explain a significant amount of brain activity in early visual regions V1, V2 and V3. However BoW exhibits more consistency across subjects in accounting for brain activity compared to HMAX. Furthermore, visual dictionary representations by HMAX and BoW explain significantly some brain activity in higher areas which are believed to process intermediate features. Overall our results indicate that, although both HMAX and BoW account for activity in the human visual system, the BoW seems to more faithfully represent neural responses in low and intermediate level visual areas of the brain.

  8. Reactor-moderated intermediate-energy neutron beams for neutron-capture therapy

    International Nuclear Information System (INIS)

    Less, T.J.

    1987-01-01

    One approach to producing an intermediate energy beam is moderating fission neutrons escaping from a reactor core. The objective of this research is to evaluate materials that might produce an intermediate beam for NCT via moderation of fission neutrons. A second objective is to use the more promising moderator material in a preliminary design of an NCT facility at a research reactor. The evaluations showed that several materials or combinations of materials could produce a moderator source for an intermediate beam for NCT. The best neutron spectrum for use in NCT is produced by Al 2 O 3 , but mixtures of Al metal and D 2 O are also attractive. Using the best moderator materials, results were applied to the design of an NCT moderator at the Georgia Institute of Technology Research Reactor's bio-medical facility. The amount of photon shielding and thermal neutron absorber were optimized with respect to the desired photon dose rate and intermediate neutron flux at the patient position

  9. Energy policy, ethics, and a return to civility

    International Nuclear Information System (INIS)

    Pickering, G.W.

    1985-01-01

    For the past decade or so government, business and the general public have been concerned with framing a coherent set of energy policies that will meet our present responsibilities and secure an adequate and diversified energy future of a nation. Thinking about these policies and the possible sources of energy supply that we might be able to rely on has involved, in addition to the customary technical and commercial considerations, certain ethical issues as well. In this context the author discusses, 1) energy policy, price deregulation and distributive justice, 2) energy policy, social policy and basic goods, 3) the energy-environment-safety debate and 4) nuclear waste management

  10. Are Sexual and Reproductive Health Policies Designed for All? Vulnerable Groups in Policy Documents of Four European Countries and Their Involvement in Policy Development.

    Science.gov (United States)

    Ivanova, Olena; Dræbel, Tania; Tellier, Siri

    2015-08-12

    Health policies are important instruments for improving population health. However, experience suggests that policies designed for the whole population do not always benefit the most vulnerable. Participation of vulnerable groups in the policy-making process provides an opportunity for them to influence decisions related to their health, and also to exercise their rights. This paper presents the findings from a study that explored how vulnerable groups and principles of human rights are incorporated into national sexual and reproductive health (SRH) policies of 4 selected countries (Spain, Scotland, Republic of Moldova, and Ukraine). It also aimed at discussing the involvement of vulnerable groups in SRH policy development from the perspective of policy-makers. Literature review, health policy analysis and 5 semi-structured interviews with policy-makers were carried out in this study. Content analysis of SRH policies was performed using the EquiFrame analytical framework. The study revealed that vulnerable groups and core principles of human rights are differently addressed in SRH policies within 4 studied countries. The opinions of policy-makers on the importance of mentioning vulnerable groups in policy documents and the way they ought to be mentioned varied, but they agreed that a clear definition of vulnerability, practical examples, and evidences on health status of these groups have to be included. In addition, different approaches to vulnerable group's involvement in policy development were identified during the interviews and the range of obstacles to this process was discussed by respondents. Incorporation of vulnerable groups in the SRH policies and their involvement in policy development were found to be important in addressing SRH of these groups and providing an opportunity for them to advocate for equal access to healthcare and exercise their rights. Future research on this topic should include representatives of vulnerable communities which could

  11. Characteristics of intermediate-energy nucleons emitted from 50 GeV

    International Nuclear Information System (INIS)

    Goyal, D.P.; Singh, S.; Arya, N.S.

    1984-01-01

    The multiplicity and angular distributions of intermediate-energy (grey) nucleons are studied from 50 GeV π - -nucleus data and compared with those available from π - -nucleus and p-nucleus interactions at other energies. The value of is found to be dependent both on the energy as well as on the projectile. The former variation is attributable to kinematics and the latter explainable on the basis of the additive quark model. The angular distribution of grey particles is found to be independent of energy, projectile and target, which supports the view that grey particles are chiefly due to knock-on recoiling protons. The various versions of the cascade model, however, are unable to explain any of the observed features of grey-particle distributions

  12. File list: DNS.PSC.20.AllAg.iPSC_intermediates [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available DNS.PSC.20.AllAg.iPSC_intermediates mm9 DNase-seq Pluripotent stem cell iPSC intermediates... http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/DNS.PSC.20.AllAg.iPSC_intermediates.bed ...

  13. File list: DNS.PSC.10.AllAg.iPSC_intermediates [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available DNS.PSC.10.AllAg.iPSC_intermediates mm9 DNase-seq Pluripotent stem cell iPSC intermediates... http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/DNS.PSC.10.AllAg.iPSC_intermediates.bed ...

  14. File list: DNS.PSC.05.AllAg.iPSC_intermediates [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available DNS.PSC.05.AllAg.iPSC_intermediates mm9 DNase-seq Pluripotent stem cell iPSC intermediates... http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/DNS.PSC.05.AllAg.iPSC_intermediates.bed ...

  15. Intermediality and the Child Performer

    Science.gov (United States)

    Budd, Natasha

    2016-01-01

    This report details examples of praxis in the creation and presentation of "Joy Fear and Poetry": an intermedial theatre performance in which children aged 7-12 years generated aesthetic gestures using a range of new media forms. The impetus for the work's development was a desire to make an intervention into habituated patterns of…

  16. Renewable energy policy evaluation using real option model. The case of Taiwan

    International Nuclear Information System (INIS)

    Lee, Shun-Chung; Shih, Li-Hsing

    2010-01-01

    This study presents a policy benefit evaluation model that integrates cost efficiency curve information on renewable power generation technologies into real options analysis (ROA) methods. The proposed model evaluates quantitatively the policy value provided by developing renewable energy (RE) in the face of uncertain fossil fuel prices and RE policy-related factors. The economic intuition underlying the policy-making process is elucidated, while empirical analysis illustrates the option value embedded in the current development policy in Taiwan for wind power. In addition to revealing the benefits that RE development provides when considering real options, analytical results indicate that ROA is a highly effective means of quantifying how policy planning uncertainty including managerial flexibility influences RE development. In addition to assessing the policy value of current RE development policy, this study also compares policy values in terms of internalized external costs and varying feed-in tariff (FIT). Simulation results demonstrate that the RE development policy with internalized CO 2 emission costs is appropriate policy planning from sustainability point of view. Furthermore, relationship between varying FIT and policy values can be shown quantitatively and appropriate FIT level could be determined accordingly. (author)

  17. Bioorthogonal Cycloadditions with Sub-Millisecond Intermediates.

    Science.gov (United States)

    Qing, Yujia; Pulcu, Gökçe Su; Bell, Nicholas A W; Bayley, Hagan

    2018-01-26

    Tetrazine- and sydnone-based click reactions have emerged as important bioconjugation strategies with fast kinetics and N 2 or CO 2 as the only byproduct. Mechanistic studies of these reactions have focused on the initial rate-determining cycloaddition steps. The subsequent N 2 or CO 2 release from the bicyclic intermediates has been approached mainly through computational studies, which have predicted lifetimes of femtoseconds. In the present study, bioorthogonal cycloadditions involving N 2 or CO 2 extrusion have been examined experimentally at the single-molecule level by using a protein nanoreactor. At the resolution of this approach, the reactions appeared to occur in a single step, which places an upper limit on the lifetimes of the intermediates of about 80 μs, which is consistent with the computational work. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. Intermediate L-K molecular orbital radiation from heavy ion collisions

    International Nuclear Information System (INIS)

    Heinig, K.H.; Jaeger, H.U.; Richter, H.; Woittennek, H.

    1975-09-01

    The structure of x-ray continua observed recently in violent collisions between intermediate mass atoms can be explained by a superposition of K molecular orbital (KMO) radiation and of an intermediate L-K molecular orbital (ILKMO) radiation of high intensity which is due to 2psigma vacancies. (author)

  19. Is Adjuvant Chemoradiotherapy Overtreatment in Cervical Cancer Patients With Intermediate Risk Factors?

    International Nuclear Information System (INIS)

    Ryu, Sang-Young; Park, Sang-Il; Nam, Byung-Ho; Cho, Chul-Koo; Kim, Kidong; Kim, Beob-Jong; Kim, Moon-Hong; Choi, Seok-Cheol; Lee, Eui-Don; Lee, Kyoung-Hee

    2011-01-01

    Purpose: To determine whether adjuvant chemoradiotherapy (CRT) improves the outcome of cervical cancer patients with intermediate risk factors. Methods and Materials: Between January 2000 and June 2006, the medical records of 735 patients who had undergone radical surgery for Stage IB-IIA cervical cancer were reviewed retrospectively. Of the 735 patients, 172 with two or more intermediate risk factors (i.e., lymphovascular space involvement, deep stromal invasion, and tumor size ≥2 cm) were grouped as follows according to the adjuvant treatment received: 34 patients, no further treatment; 49 patients, RT; and 89 patients, CRT. The significance of the clinical parameters and recurrence-free survival of each group were analyzed. Results: Of the 172 patients with any of the intermediate risk factors, 137 (79.6%) had two or more intermediate risk factors. Of the 172 patients, 12 developed recurrences (6.4%)->(7.0%), with 6 in the pelvis and 6 in distant sites. All 12 recurrences occurred in those who had two or more intermediate risk factors (sensitivity, 100%); however, only six recurrences were detected in patients who met the Gynecologic Oncology Group criteria for the intermediate-risk group (sensitivity, 50%; Z test, p .05). Conclusion: Postoperative adjuvant CRT can improve the outcome of cervical cancer patients with intermediate risk factors, with low increase in toxicity.

  20. Monetary policy and regional output in Brazil

    Directory of Open Access Journals (Sweden)

    Rafael Rockenbach da Silva Guimarães

    2014-03-01

    Full Text Available This work presents an analysis of whether the effects of the Brazilian monetary policy on regional outputs are symmetric. The strategy developed combines the techniques of principal component analysis (PCA to decompose the variables that measure regional economic activity into common and region-specific components and vector autoregressions (VAR to observe the behavior of these variables in response to monetary policy shocks. The common component responds to monetary policy as expected. Additionally, the idiosyncratic components of the regions showed no impact of monetary policy. The main finding of this paper is that the monetary policy responses on regional output are symmetrical when the regional output decomposition is performed, and the responses are asymmetrical when this decomposition is not performed. Therefore, performing the regional output decomposition corroborates the economic intuition that monetary policy has no impact on region-specific issues. Once monetary policy affects the common component of the regional economic activity and does not impact its idiosyncratic components, it can be considered symmetrical.

  1. Policy packages to achieve demand reduction

    International Nuclear Information System (INIS)

    Boardman, Brenda

    2005-01-01

    In many sectors and many countries, energy demand is still increasing, despite decades of policies to reduce demand. Controlling climate change is becoming more urgent, so there is a need to devise policies that will, virtually, guarantee demand reduction. This has to come from policy, at least in the UK, as the conditions do not exist, yet, when the consumers will 'pull' the market for energy efficiency or the manufacturers will use technological development to 'push' it. That virtuous circle has to be created by a mixture of consumer education and restrictions on manufacturers (for instance, permission to manufacture). The wider policy options include higher prices for energy and stronger product policies. An assessment of the effectiveness of different policy packages indicates some guiding principles, for instance that improved product policy must precede higher prices, otherwise consumers are unable to react effectively to price rises. The evidence will be assessed about the ways in which national and EU policies can either reinforce, duplicate or undermine each other. Another area of examination will be timescales: what is the time lag between the implementation of a policy (whether prices or product based) and the level of maximum reductions. In addition, the emphasis given to factors such as equity, raising investment funds and speed of delivery also influence policy design and the extent to which absolute carbon reductions can be expected

  2. Optimal design of the cable metro with unified intermediate supports

    Directory of Open Access Journals (Sweden)

    Lagerev A.V.

    2017-12-01

    Full Text Available In article was formulated and solved the problem of conditional nonlinear technical and economic optimization of the distance between intermediate supports, uniform in height, during the design of the cable metro lines in highly urban-ized city environment. The optimization problem involves a single-criterion objective function that expresses the cost of construction of the cable metro line (total cost of intermediate supports and their foundations, traction and carrying steel cables and technical equipment. The specified objective function subject to minimization by finding the optimal combination of the distance between intermediate supports and tension carrying ropes with accounting constructive, modal, structural and planning constraints in the form of nonlinear inequalities. The optimization algorithm was based on the direct method of optimization type, Hooke-Jeeves, which was modified taking into account the need of varying the height of intermediate supports with a constant step equal to the step of unification. When constructing the objective function were considered three possible forms sagging of carrying ropes, which can be implemented for various values of the efforts of their tension. Analysis was done of the influence of the step unification and minimum size of interme-diate supports on their optimum step, the cost of intermediate supports, the cost of 1 km cable metro line for different values of the angle of the longitudinal slope of the surface relief along the cable metro line. The graph of height of uni-fied supports from the angle of the longitudinal slope of the surface relief has discrete-step type. With the increase of the step unify the discreteness increases: the width of the range of angles of the longitudinal slope of the surface relief within which the height of the supports remains constant, increases. The graph of step installation of unified supports along the cable metro line from the angle of the longitudinal

  3. Role of hormonal therapy in the management of intermediate- to high-risk prostate cancer treated with permanent radioactive seed implantation

    International Nuclear Information System (INIS)

    Lee, Lucille N.; Stock, Richard G.; Stone, Nelson N.

    2002-01-01

    Purpose: To study the impact of hormonal therapy (HTx) on intermediate- to high-risk prostate cancer treated with permanent radioactive seed implantation. Methods and Materials: Patients with Stage T1b-T3bN0 prostate cancer, and Gleason score ≥7 or prostate-specific antigen (PSA) level >10 ng/mL were treated with seed implantation with or without HTx. Their disease was defined as intermediate risk (PSA 10-20, Gleason score 7, or Stage T2b) or high risk (two or more intermediate criteria, or PSA >20 ng/mL, Gleason score 8-10, or Stage T2c-T3). The median follow-up for 201 eligible patients was 42 months (range 18-110). Biochemical failure was defined as a rising PSA >1.0 ng/mL. Pretreatment disease characteristics, implant dose, and HTx were evaluated using univariate and multivariate analyses. Results: HTx significantly improved 5-year actuarial freedom from biochemical failure rate, 79% vs. 54% without HTx. In addition, high-dose, PSA ≤15 ng/mL, intermediate risk, and Stage T2a or lower significantly improved outcome in the univariate analyses. HTx was the most significant predictor of 5-year actuarial freedom from biochemical failure (p <0.0001) in a multivariate analysis. The best outcome was in the intermediate-risk patients treated with a high implant dose and HTx, resulting in a 4-year actuarial freedom from biochemical failure rate of 94%. Conclusion: In this retrospective review, HTx improved outcome in intermediate- to high-risk prostate cancer patients treated with brachytherapy. HTx was the most important prognostic factor in the univariate and multivariate analyses

  4. What are the costs of Scotland's climate and renewable policies?

    International Nuclear Information System (INIS)

    Anandarajah, Gabrial; McDowall, Will

    2012-01-01

    The UK government has established ambitious policies to address climate change and promote renewable energy, and has set targets both for reducing carbon emissions and for deploying renewables. Scotland, a constituent nation of the UK, has also set its own targets for climate change mitigation and renewable electricity. This paper analyses the energy, economic and environmental implications of carbon and renewable electricity targets in Scotland and the UK using a newly developed two-region UK MARKAL energy system model, where Scotland (SCT) and rest of the UK (RUK) are the two regions. The paper shows that meeting Scotland's carbon targets does not require additional decarbonisation effort if the UK meets its own targets at least cost; and that Scotland's renewable energy ambitions do imply additional costs above the least cost path to the meeting the UK's obligations under the EU renewable energy directive. Meeting Scottish renewable electricity targets diverts investment and deployment in renewables from rest of the UK to Scotland. In addition to increased energy system cost, Scottish renewable electricity targets may also require early investment in new electricity transmission capacity between Scotland and rest of the UK. - Highlights: ► Scottish climate policy is less stringent than UK policy. ► Scottish targets would complement UK targets if UK policies fail to meet UK targets. ► The possible conclusion here is that Scottish carbon targets are unnecessary. ► Scottish renewable policy is more stringent than UK policy. ► As expected, this increased stringency leads to additional costs.

  5. High temperature salt corrosion cracking of intermediate products of titanium alloys

    International Nuclear Information System (INIS)

    Sinyavskij, V.S.; Usova, V.V.; Lunina, S.I.; Kushakevich, S.A.; Makhmutova, E.A.; Khanina, Z.K.

    1982-01-01

    The high temperature salt corrosion cracking (HTSCC) of intermediate products from titanium base alloys in the form of hot rolled plates and rods has been studied. The investigated materials are as follows: VT20 pseudo-α-alloy, VT6 and VT14 α+β alloys; the comparison has been carried out with commercial titanium and low-alloyed OT4-1 α-alloy. The experiments have been held at 400 and 500 deg C, defining different stress levels: 0.4; 0.5; 0.75 and 0.9 tausub(0.2). The test basis - not less than 100 h. Standard tensile samples of circular cross section with NaCl (approximately 0.2-0.3 mg/cm 2 ) salt coatings, cut off from hot-rolled rods along the direction of rolling and hot-rolled plates along and across the direction of rolling have been tested. It has been extablished before hand that the notch doesn't affect the resistance of titanium alloys to HTSCC. The sensitivity of titanium alloy subproducts to HTSCC is estimated as to the time until the failure of the sample with salt coatings and without them. It is shown that salt coating practically doesn't affect the behaviour of titanium, that allows to consider it to be resistant to HTSCC. Titanium alloys alloying with β-isomorphous stabilizing additions increases it's HTSCC resistance. Vanadium alloying of the alloy (VT6 alloy of Ti-Al-V system) produces a favourable effect; intermediate products of VT14 (α+β) alloy (Ti-Al-V-Mo system), containing two β-stabilizing additions-vanadium and molybdenum, have satisfactory HTSCC resistance. It is shown that by changes is mechanical properties of alloys during HTSCC one can indirectly judge about their HTSCC sensitivity

  6. Quantifying policy options for reducing future coronary heart disease mortality in England: a modelling study.

    Directory of Open Access Journals (Sweden)

    Shaun Scholes

    Full Text Available To estimate the number of coronary heart disease (CHD deaths potentially preventable in England in 2020 comparing four risk factor change scenarios.Using 2007 as baseline, the IMPACTSEC model was extended to estimate the potential number of CHD deaths preventable in England in 2020 by age, gender and Index of Multiple Deprivation 2007 quintiles given four risk factor change scenarios: (a assuming recent trends will continue; (b assuming optimal but feasible levels already achieved elsewhere; (c an intermediate point, halfway between current and optimal levels; and (d assuming plateauing or worsening levels, the worst case scenario. These four scenarios were compared to the baseline scenario with both risk factors and CHD mortality rates remaining at 2007 levels. This would result in approximately 97,000 CHD deaths in 2020. Assuming recent trends will continue would avert approximately 22,640 deaths (95% uncertainty interval: 20,390-24,980. There would be some 39,720 (37,120-41,900 fewer deaths in 2020 with optimal risk factor levels and 22,330 fewer (19,850-24,300 in the intermediate scenario. In the worst case scenario, 16,170 additional deaths (13,880-18,420 would occur. If optimal risk factor levels were achieved, the gap in CHD rates between the most and least deprived areas would halve with falls in systolic blood pressure, physical inactivity and total cholesterol providing the largest contributions to mortality gains.CHD mortality reductions of up to 45%, accompanied by significant reductions in area deprivation mortality disparities, would be possible by implementing optimal preventive policies.

  7. Quantifying policy options for reducing future coronary heart disease mortality in England: a modelling study.

    Science.gov (United States)

    Scholes, Shaun; Bajekal, Madhavi; Norman, Paul; O'Flaherty, Martin; Hawkins, Nathaniel; Kivimäki, Mika; Capewell, Simon; Raine, Rosalind

    2013-01-01

    To estimate the number of coronary heart disease (CHD) deaths potentially preventable in England in 2020 comparing four risk factor change scenarios. Using 2007 as baseline, the IMPACTSEC model was extended to estimate the potential number of CHD deaths preventable in England in 2020 by age, gender and Index of Multiple Deprivation 2007 quintiles given four risk factor change scenarios: (a) assuming recent trends will continue; (b) assuming optimal but feasible levels already achieved elsewhere; (c) an intermediate point, halfway between current and optimal levels; and (d) assuming plateauing or worsening levels, the worst case scenario. These four scenarios were compared to the baseline scenario with both risk factors and CHD mortality rates remaining at 2007 levels. This would result in approximately 97,000 CHD deaths in 2020. Assuming recent trends will continue would avert approximately 22,640 deaths (95% uncertainty interval: 20,390-24,980). There would be some 39,720 (37,120-41,900) fewer deaths in 2020 with optimal risk factor levels and 22,330 fewer (19,850-24,300) in the intermediate scenario. In the worst case scenario, 16,170 additional deaths (13,880-18,420) would occur. If optimal risk factor levels were achieved, the gap in CHD rates between the most and least deprived areas would halve with falls in systolic blood pressure, physical inactivity and total cholesterol providing the largest contributions to mortality gains. CHD mortality reductions of up to 45%, accompanied by significant reductions in area deprivation mortality disparities, would be possible by implementing optimal preventive policies.

  8. Intermediate coupling collision strengths from LS coupled R-matrix elements

    International Nuclear Information System (INIS)

    Clark, R.E.H.

    1978-01-01

    Fine structure collision strength for transitions between two groups of states in intermediate coupling and with inclusion of configuration mixing are obtained from LS coupled reactance matrix elements (R-matrix elements) and a set of mixing coefficients. The LS coupled R-matrix elements are transformed to pair coupling using Wigner 6-j coefficients. From these pair coupled R-matrix elements together with a set of mixing coefficients, R-matrix elements are obtained which include the intermediate coupling and configuration mixing effects. Finally, from the latter R-matrix elements, collision strengths for fine structure transitions are computed (with inclusion of both intermediate coupling and configuration mixing). (Auth.)

  9. Intermediate statistics in quantum maps

    Energy Technology Data Exchange (ETDEWEB)

    Giraud, Olivier [H H Wills Physics Laboratory, University of Bristol, Tyndall Avenue, Bristol BS8 1TL (United Kingdom); Marklof, Jens [School of Mathematics, University of Bristol, University Walk, Bristol BS8 1TW (United Kingdom); O' Keefe, Stephen [School of Mathematics, University of Bristol, University Walk, Bristol BS8 1TW (United Kingdom)

    2004-07-16

    We present a one-parameter family of quantum maps whose spectral statistics are of the same intermediate type as observed in polygonal quantum billiards. Our central result is the evaluation of the spectral two-point correlation form factor at small argument, which in turn yields the asymptotic level compressibility for macroscopic correlation lengths. (letter to the editor)

  10. Determination Bounds for Intermediate Products in a Two-Stage Network DEA

    Directory of Open Access Journals (Sweden)

    Hadi Bagherzadeh Valami

    2016-03-01

    Full Text Available The internal structure of decision making unit (DMU is the key element at extension of network DEA. In general considering internal performance evaluation of system is a better criterion than the conventional DEA-models, essentially based on the initial inputs and final outputs of the system. The internal performance of a system is dependent on the relation between sub-DMUs and intermediate products. Since the intermediate measures are consumed by some sub-DMUs produced by the others, it is possible to produce systems; the role of intermediate production is twice output and input. That's why they can be analyzed based on conventional mathematical modeling. In this paper we introduce a new method for determining bounds for intermediate product in a two stage network DEA structure.

  11. Unification of favourable intermediate-, unfavourable intermediate-, and very high-risk stratification criteria for prostate cancer.

    Science.gov (United States)

    Zumsteg, Zachary S; Zelefsky, Michael J; Woo, Kaitlin M; Spratt, Daniel E; Kollmeier, Marisa A; McBride, Sean; Pei, Xin; Sandler, Howard M; Zhang, Zhigang

    2017-11-01

    To improve on the existing risk-stratification systems for prostate cancer. This was a retrospective investigation including 2 248 patients undergoing dose-escalated external beam radiotherapy (EBRT) at a single institution. We separated National Comprehensive Cancer Network (NCCN) intermediate-risk prostate cancer into 'favourable' and 'unfavourable' groups based on primary Gleason pattern, percentage of positive biopsy cores (PPBC), and number of NCCN intermediate-risk factors. Similarly, NCCN high-risk prostate cancer was stratified into 'standard' and 'very high-risk' groups based on primary Gleason pattern, PPBC, number of NCCN high-risk factors, and stage T3b-T4 disease. Patients with unfavourable-intermediate-risk (UIR) prostate cancer had significantly inferior prostate-specific antigen relapse-free survival (PSA-RFS, P prostate cancer-specific mortality (PCSM, P prostate cancer. Similarly, patients with very high-risk (VHR) prostate cancer had significantly worse PSA-RFS (P prostate cancer. Moreover, patients with FIR and low-risk prostate cancer had similar outcomes, as did patients with UIR and SHR prostate cancer. Consequently, we propose the following risk-stratification system: Group 1, low risk and FIR; Group 2, UIR and SHR; and Group 3, VHR. These groups have markedly different outcomes, with 8-year distant metastasis rates of 3%, 9%, and 29% (P < 0.001) for Groups 1, 2, and 3, respectively, and 8-year PCSM of 1%, 4%, and 13% (P < 0.001) after EBRT. This modified stratification system was significantly more accurate than the three-tiered NCCN system currently in clinical use for all outcomes. Modifying the NCCN risk-stratification system to group FIR with low-risk patients and UIR with SHR patients, results in modestly improved prediction of outcomes, potentially allowing better personalisation of therapeutic recommendations. © 2017 The Authors BJU International © 2017 BJU International Published by John Wiley & Sons Ltd.

  12. Isomerization Intermediates In Solution Phase Photochemistry Of Stilbenes

    Science.gov (United States)

    Doany, F. E.; Hochstrasser, R. M.; Greene, B. I.

    1985-04-01

    Picosecond and subpicosecond spectroscopic studies have revealed evidence for an isomerization intermediate between cis and trans in the photoinduced isomerism of both stilbene and biindanyledene ("stiff" stilbene). In stiff stilbene, a transient absorption at 351 nm displays time evolution and viscosity dependence consistent with absorption by a twisted intermediate ("phantom" state) with a lOps lifetime. An analagous bottleneck state with a life-time of 4ps is also consistent with the ground state recovery dynamics of t-stilbene following excitation of c-stilbene when monitored with 0.1ps resolution.

  13. Are Sexual and Reproductive Health Policies Designed for All? Vulnerable Groups in Policy Documents of Four European Countries and Their Involvement in Policy Development

    Directory of Open Access Journals (Sweden)

    Olena Ivanova

    2015-10-01

    Full Text Available Background Health policies are important instruments for improving population health. However, experience suggests that policies designed for the whole population do not always benefit the most vulnerable. Participation of vulnerable groups in the policy-making process provides an opportunity for them to influence decisions related to their health, and also to exercise their rights. This paper presents the findings from a study that explored how vulnerable groups and principles of human rights are incorporated into national sexual and reproductive health (SRH policies of 4 selected countries (Spain, Scotland, Republic of Moldova, and Ukraine. It also aimed at discussing the involvement of vulnerable groups in SRH policy development from the perspective of policymakers. Methods Literature review, health policy analysis and 5 semi-structured interviews with policy-makers were carried out in this study. Content analysis of SRH policies was performed using the EquiFrame analytical framework. Results The study revealed that vulnerable groups and core principles of human rights are differently addressed in SRH policies within 4 studied countries. The opinions of policy-makers on the importance of mentioning vulnerable groups in policy documents and the way they ought to be mentioned varied, but they agreed that a clear definition of vulnerability, practical examples, and evidences on health status of these groups have to be included. In addition, different approaches to vulnerable group’s involvement in policy development were identified during the interviews and the range of obstacles to this process was discussed by respondents. Conclusion Incorporation of vulnerable groups in the SRH policies and their involvement in policy development were found to be important in addressing SRH of these groups and providing an opportunity for them to advocate for equal access to healthcare and exercise their rights. Future research on this topic should include

  14. Construction Policies on Campus An Analytical Study of the Policy of Construction Planning on Kufa Campus

    Directory of Open Access Journals (Sweden)

    Talib Hamid Altalib

    2017-06-01

    Full Text Available University Campuses, as any lively physical entity, is subject to continuous variation due to . growth, development and change. This reality covers the existing or futuristic additives or additions, consecutively these changes may have a strong sensation of disorientation as a result of formatic changes in buildings, or in movement paths. And it epitomized the research problem to "the need for knowledge to clarify the impact of intellectual and executive policy in achieving coherence, functional and space organization of the elements of the university urban environment and in the stages of future growth and change," the search targeted "to highlight the study of constraction politics on campus Bmqomadtha intellectual and executive , as well as clarify the role of the executive policy in the application of thought, "and formulated the hypothesis search " urban policy affect Bmqomadtha (intellectual and executive on the process of organizing and homogeneity of the university urban environment to make them adapted to future changes, "the University of Kufa it was chosen as the campus to represent the experimental field of research.

  15. 48 CFR 410.001 - Policy.

    Science.gov (United States)

    2010-10-01

    ... PLANNING MARKET RESEARCH 410.001 Policy. In addition to those uses listed in FAR 10.001, agencies must use the results of market research to— (a) Ensure the minimum use of hazardous or toxic materials; (b...

  16. European policies in the management of tuberculosis among migrants

    Directory of Open Access Journals (Sweden)

    Lia D’Ambrosio

    2017-03-01

    Full Text Available Globally 10.4 million new tuberculosis (TB incident cases were estimated to have occurred in 2015, of which 3% were reported in the World Health Organization European Region. Importantly, about 25% of the global multidrug-resistant TB (MDR-TB cases are reported in the European Region, representing one of the greatest challenges to TB control; these are reported particularly in the countries of the Former Soviet Union. Over a quarter of TB cases in the European Union and European Economic Area (EU/EEA are reported among foreign-born individuals. In line with the recent increase of migration flows towards Europe, TB among migrant populations is also on the rise, emphasizing the need for a better understanding of the TB trends at the regional and sub-regional levels, and of the existing policies on migrants and refugees. The present article is aimed at describing the policies and practices of European countries with a low and intermediate TB incidence with regard to the detection and management of TB and latent TB infection (LTBI among refugees in Europe.

  17. Monte Carlo cross section testing for thermal and intermediate 235U/238U critical assemblies, ENDF/B-V vs ENDF/B-VI

    International Nuclear Information System (INIS)

    Weinman, J.P.

    1997-06-01

    The purpose of this study is to investigate the eigenvalue sensitivity to changes in ENDF/B-V and ENDF/B-VI cross section data sets by comparing RACER vectorized Monte Carlo calculations for several thermal and intermediate spectrum critical experiments. Nineteen Oak Ridge and Rocky Flats thermal solution benchmark critical assemblies that span a range of hydrogen-to- 235 U (H/U) concentrations (2052 to 27.1) and above-thermal neutron leakage fractions (0.555 to 0.011) were analyzed. In addition, three intermediate spectrum critical assemblies (UH3-UR, UH3-NI, and HISS-HUG) were studied

  18. To what extent are Canadian second language policies evidence-based? Reflections on the intersections of research and policy.

    Science.gov (United States)

    Cummins, Jim

    2014-01-01

    THE PAPER ADDRESSES THE INTERSECTIONS BETWEEN RESEARCH FINDINGS AND CANADIAN EDUCATIONAL POLICIES FOCUSING ON FOUR MAJOR AREAS: (a) core and immersion programs for the teaching of French to Anglophone students, (b) policies concerning the learning of English and French by students from immigrant backgrounds, (c) heritage language teaching, and (d) the education of Deaf and hard-of hearing students. With respect to the teaching of French, policy-makers have largely ignored the fact that most core French programs produce meager results for the vast majority of students. Only a small proportion of students (languages, preferring instead to leave uncorrected the proposition that acquisition of languages such as American Sign Language by young children (with or without cochlear implants) will impede children's language and academic development. The paper reviews the kinds of policies, programs, and practices that could be implemented (at no additional cost) if policy-makers and educators pursued evidence-based educational policies.

  19. Post-crisis financial intermediation

    Directory of Open Access Journals (Sweden)

    Ilie MIHAI

    2015-09-01

    Full Text Available The recent financial crisis that begun in 2007 in the US, which then swept around the world, has left deep scars on the already wrinkled face of the global economy. Some national and regional economies, which had money for expensive makeup, or created money[1], managed to blur or hide the scars left by the crisis, others are still facing difficulties in overcoming the effects of this. The rapacity of banks, their greed and risk ignorance, were the origin of the outbreak of the last major economic and financial crisis but unfortunately those who were responsible or, rather, irresponsible, paid little or nothing at all for the burden of their bad loan portfolio. This cost has been supported by the population, either directly by paying high interest and fees [Mihai I., 2007], or indirectly, through the use of public budgets to cover the losses of banks, most of which had private capital. In this context, we intend to examine the state of financial intermediation in Romania in the post-crisis period, and to primarily follow: (i The structure and evolution of the banking system; (ii Non-government credit situation; (iii The level of savings; (iiii Loan-deposit ratio; (v The degree of financial intermediation and disintegration phenomenon etc., and to articulate some conclusions and suggestions on the matters that have been explored.

  20. Positioning women's and children's health in African union policy-making: a policy analysis

    Directory of Open Access Journals (Sweden)

    Toure Kadidiatou

    2012-02-01

    looking at investments and impact. AU policies related to reproductive, maternal, newborn and child health also use fewer policy frames than do AU policies related to HIV/AIDS, tuberculosis and malaria. Conclusion We suggest that more effective prioritization of women's and children's health in African Union policies would be supported by widening the range of policy frames used (notably health and economic and strengthening the evidence base of all policy frames used. In addition, we suggest it would be beneficial if the partner groups advocating for women's and children's health were multi-stakeholder, and included, for instance, health care professionals, regional institutions, parliamentarians, the media, academia, NGOs, development partners and the public and private sectors.

  1. Positioning women's and children's health in African union policy-making: a policy analysis.

    Science.gov (United States)

    Toure, Kadidiatou; Sankore, Rotimi; Kuruvilla, Shyama; Scolaro, Elisa; Bustreo, Flavia; Osotimehin, Babatunde

    2012-02-16

    to reproductive, maternal, newborn and child health also use fewer policy frames than do AU policies related to HIV/AIDS, tuberculosis and malaria. We suggest that more effective prioritization of women's and children's health in African Union policies would be supported by widening the range of policy frames used (notably health and economic) and strengthening the evidence base of all policy frames used. In addition, we suggest it would be beneficial if the partner groups advocating for women's and children's health were multi-stakeholder, and included, for instance, health care professionals, regional institutions, parliamentarians, the media, academia, NGOs, development partners and the public and private sectors.

  2. Determination of the vildagliptin intermediate enantiomer by chiralce-columns

    Directory of Open Access Journals (Sweden)

    Weina LI

    2017-06-01

    Full Text Available In order to establish a NP-HPLC method for the determination of enantiomer in vildagliptin intermediate, the determination is carried out on the column of ChiralpakAD-H(250 mm×4.6 mm, 5 μm, with the mobile phase of n-hexane, ethanol and methanol(volume ratio of 65∶25∶10)at flow rate of 0.8 mL/min. The sample volume is 10 μL, the wavelength is 210 nm and the column temperature is 35 ℃. The result shows that the vildagliptin intermediate and its enantiomer could be well separated and detected effectively; blank solvent doesn't interfere with the enantiomer assaying; the detection limit is 27 ng/mL and the quantification limit is 81 ng/mL; in repetitive test, the RSD of enantiomer assaying of samples are no more than 2.0%; in stability test, the RSD are no more than 2.0% in 12 h; the vildagliptin intermediate and its enantiomer could be well separated in the test of durability with all RSDs below 2.0%. The method is simple, reliable, accurate and durable, and can be used for determination of enantiomer in vildagliptin intermediate.

  3. Continuous Flow-Resonance Raman Spectroscopy of an Intermediate Redox State of Cytochrome-C

    DEFF Research Database (Denmark)

    Forster, M.; Hester, R. E.; Cartling, B.

    1982-01-01

    An intermediate redox state of cytochrome c at alkaline pH, generated upon rapid reduction by sodium dithionite, has been observed by resonance Raman (RR) spectroscopy in combination with the continuous flow technique. The RR spectrum of the intermediate state is reported for excitation both...... in the (alpha, beta) and the Soret optical absorption band. The spectra of the intermediate state are more like those of the stable reduced form than those of the stable oxidized form. For excitation of 514.5 nm, the most prominent indication of an intermediate state is the wave-number shift of one RR band from...... 1,562 cm-1 in the stable oxidized state through 1,535 cm-1 in the intermediate state to 1,544 cm-1 in the stable reduced state. For excitation at 413.1 nm, a band, present at 1,542 cm-1 in the stable reduced state but not present in the stable oxidized state, is absent in the intermediate state. We...

  4. Photolysis of nonylphenol ethoxylates: the determination of the degradation kinetics and the intermediate products.

    Science.gov (United States)

    Chen, Ling; Zhou, Hai-Yun; Deng, Qin-Ying

    2007-06-01

    The photolysis of nonylphenol ethoxylates with an average oligomers length of ten ethoxylate units (NPEO(10)) in aqueous solution under UV, as well as the influence of humic acid (HA) on the photolysis was studied. A 125W high-pressure mercury lamp was employed as the light source. The intermediate products from the photolysis were determined by LC-MS. The results indicated that NPEO(10) underwent direct photolysis upon exposed to UV. The degradation pathway was complex. Besides the generally proposed degradation pathway of ethylene oxide (EO) side chains shortening, the oxidation of alkyl chain and EO chain led to intermediates having both a carboxylated (as well as carbonylated) ethoxylate and alkyl chain of varying lengths. The hydrogenation of benzene ring was also detected. The kinetics data showed that the first order reaction kinetics could be well used to describe the kinetics of NPEO(10) degradation. In the presence of dissolved organic matter by HA addition, the performance of NPEO(10) photodegradation was reduced. The photolysis rate decreased with increased HA concentration.

  5. Tax policy at the outskirts of EU

    DEFF Research Database (Denmark)

    Vesterø Jensen, Carsten; Nielsen, Søren Bo

    2003-01-01

    of Greenland's tax system, the paper's special focus will be on the corporate tax systemand its interplay with personal taxation, as well on as the system of import duties. In particular, wecarry out computations of effective marginal and average corporate tax rates, as well as average effectivetax burdens...... on consumption, labour income and capital income, and compare these to similarmeasures for EU countries. In addition, we outline how Greenland's economic policy in other areasinterferes with tax policy. Especially fishery regulation, management of government-owned companies,and housing policy have major...

  6. DEVELOPING STATE POLICIES SUPPORTIVE OF BIOENERGY DEVELOPMENT

    International Nuclear Information System (INIS)

    Kathryn Baskin

    2001-01-01

    Working within the context of the Southern States Biobased Alliance (SSBA) and with officials in each state, the Southern States Energy Board (SSEB) is identifying bioenergy-related policies and programs within each state to determine their impact on the development, deployment or use of bioenergy. In addition, SSEB will determine which policies have impacted industry's efforts to develop, deploy or use biobased technologies or products. As a result, SSEB will work with the Southern States Biobased Alliance to determine how policy changes might address any negative impacts or enhance positive impacts

  7. DEVELOPING STATE POLICIES SUPPORTIVE OF BIOENERGY DEVELOPMENT

    International Nuclear Information System (INIS)

    Kathryn Baskin

    2002-01-01

    Working within the context of the Southern States Biobased Alliance (SSBA) and with officials in each state, the Southern States Energy Board (SSEB) is identifying bioenergy-related policies and programs within each state to determine their impact on the development, deployment or use of bioenergy. In addition, SSEB will determine which policies have impacted industry's efforts to develop, deploy or use biobased technologies or products. As a result, SSEB will work with the Southern States Biobased Alliance to determine how policy changes might address any negative impacts or enhance positive impacts

  8. Synchrotron photoionization mass spectrometry study of intermediates in fuel-rich 1,2-dimethoxyethane flame

    International Nuclear Information System (INIS)

    Lin, Z. K.; Han, D. L.; Li, S. F.; Li, Y. Y.; Yuan, T.

    2009-01-01

    Intermediates in a fuel-rich premixed laminar 1,2-dimethoxyethane (DME) flame are studied by molecular beam mass spectrometry combined with tunable synchrotron vacuum ultraviolet photoionization. About 30 intermediate species are identified in the present work, and their mole fraction profiles are evaluated. The experimental results show that the formations of intermediates, both hydrocarbons and oxygenated hydrocarbons, are closely linked to the structure of fuel, which is consistent with the previous reports. Species produced from H atom abstraction and beta scission of DME usually have much higher concentrations than others. The oxygen atoms in DME are considered to act as partitions of the primary intermediates; therefore farther reactions among these primary intermediates are difficult to occur, resulting in absence of most large intermediate species.

  9. Considering Critical Turns in Research on Educational Leadership and Policy

    Science.gov (United States)

    Diem, Sarah; Young, Michelle D.

    2015-01-01

    Purpose: The purpose of this paper is to explore the use of critical policy analysis (CPA) in the fields of educational leadership and policy. In addition to exploring how CPA compares to traditional research approaches in educational leadership and policy, the authors consider the influence of long-established ways of knowing, why scholars choose…

  10. A pump/intermediate heat exchanger assembly for a liquid metal reactor

    International Nuclear Information System (INIS)

    Nathenson, R.D.; Alexion, C.C.; Sumpman, W.C.

    1987-01-01

    A heat exchanger and electromagnetic pump assembly is disclosed comprising a heat exchanger housing defining an annularly shaped cavity and supporting therein a plurality of heat transfer tubes. An electromagnetic pump disposed beneath the heat exchanger comprises a circular array of flow couplers. Each flow coupler comprises a pump duct receiving primary liquid metal and a generator duct receiving a pumped intermediate liquid metal. A first plenum chamber is in communication with the generator ducts of all the flow couplers and receives intermediate liquid metal from inlet duct. The generator ducts exit their flows of intermediate liquid metal to a second plenum chamber in communication with the heat exchanger annularly shaped cavity to permit the flow of the intermediate liquid metal therethrough. A third plenum chamber receives collectively the flows of the primary liquid metal from the tubes and directs the primary liquid metal to the pump ducts of the flow couplers. The annular magnetic field of the electromagnetic pump is produced by a circular array of electromagnets having hollow windings cooled by a flow of intermediate liquid metal via tubes and manifolds. The leads to the electromagnets pass through an annular space around the inlet duct. (author)

  11. Carbon monosulfide: a useful synthetic intermediate

    International Nuclear Information System (INIS)

    Kramer, M.P.

    1986-01-01

    The physical properties of carbon monosulfide, CS, are well documented. The molecule has been observed in interstellar space and is found to be a common intermediate in the thermal decomposition of carbon disulfide and other sulfur compounds. Interestingly enough, the chemistry of carbon monosulfide, a molecule that is isovalent with carbon monoxide, has received little attention. The explosive nature of the carbon monosulfide monomer, which hindered previous workers, was overcome by the development of special handling techniques. The ability to produce carbon monosulfide in gram quantities had lead to synthesis of novel compounds and to a more direct synthetic route for certain known compounds. Specifically, the following general reaction demonstrates the capabilities of carbon monosulfide on the synthetic scale. CS + RXY → RXC(S)Y;(X = N,S), (Y = H, Cl). Note: The initial product formed in the reaction can be an unstable intermediate

  12. Intermediate care: for better or worse? Process evaluation of an intermediate care model between a university hospital and a residential home

    Directory of Open Access Journals (Sweden)

    Janmaat Tonnie ACM

    2005-05-01

    Full Text Available Abstract Background Intermediate care was developed in order to bridge acute, primary and social care, primarily for elderly persons with complex care needs. Such bridging initiatives are intended to reduce hospital stays and improve continuity of care. Although many models assume positive effects, it is often ambiguous what the benefits are and whether they can be transferred to other settings. This is due to the heterogeneity of intermediate care models and the variety of collaborating partners that set up such models. Quantitative evaluation captures only a limited series of generic structure, process and outcome parameters. More detailed information is needed to assess the dynamics of intermediate care delivery, and to find ways to improve the quality of care. Against this background, the functioning of a low intensity early discharge model of intermediate care set up in a residential home for patients released from an Amsterdam university hospital has been evaluated. The aim of this study was to produce knowledge for management to improve quality of care, and to provide more generalisable insights into the accumulated impact of such a model. Methods A process evaluation was carried out using quantitative and qualitative methods. Registration forms and patient questionnaires were used to quantify the patient population in the model. Statistical analysis encompassed T-tests and chi-squared test to assess significance. Semi-structured interviews were conducted with 21 staff members representing all disciplines working with the model. Interviews were transcribed and analysed using both 'open' and 'framework' approaches. Results Despite high expectations, there were significant problems. A heterogeneous patient population, a relatively unqualified staff and cultural differences between both collaborating partners impeded implementation and had an impact on the functioning of the model. Conclusion We concluded that setting up a low intensity

  13. Low-energy consequences of superstring-inspired models with intermediate-mass scales

    International Nuclear Information System (INIS)

    Gabbiani, F.

    1987-01-01

    The phenomenological consequences of implementing intermediate-mass scales in E 6 superstring-inspired models are discussed. Starting from a suitable Calabi-Yau compactification with b 1,1 >1, one gets, after Hosotani breaking, the rank r=5 gauge group SU(3) C x SU(2) L x U(1) Y x U(1) E , that is broken at an intermediate-mass scale down to the standard-model group. The analysis of both the intermediate and the electroweak breaking is performed in the two cases Λ c = M x and Λ c x , where Λ c is the scale at which the hidden sector gauginos condensate. It is performed quantitatively the minimization of the low-energy effective potential and the renormalization group analysis, yielding a viable set of mass spectra and confirming the reliability of the intermediate-breaking scheme

  14. ESL intermediate/advanced writing

    CERN Document Server

    Munoz Page, Mary Ellen; Jaskiewicz, Mary

    2011-01-01

    Master ESL (English as a Second Language) Writing with the study guide designed for non-native speakers of English. Skill-building lessons relevant to today's topics help ESL students write complete sentences, paragraphs, and even multi-paragraph essays. It's perfect for classroom use or self-guided writing preparation.DETAILS- Intermediate drills for improving skills with parallel structure, mood, correct shifting errors & dangling participles- Advanced essay drills focusing on narrative, descriptive, process, reaction, comparison and contrast- Superb preparation for students taking the TOEFL

  15. Best Practice in Policy Package Design

    DEFF Research Database (Denmark)

    Kessler, Florian; Vesela, Jirina; Vencl, Vaclav

    2010-01-01

    This deliverable focuses on the identification and analysis of best practice examples of policy package design. For this purpose a methodology is developed that allows the systematic analysis of both national and EU policy packages. Eight packages were selected and analysed, highlighting...... the factors which supported the design and implementation process in each case. The results of the analysis show which factors led to these cases to be considered best practice. In addition, factors are identified which are not yet part of the generic policy packaging framework presented in earlier OPTIC...... Deliverables. The consideration of these factors will help to further improve the framework in the subsequent work packages....

  16. Spectro-Timing Study of GX 339-4 in a Hard Intermediate State

    DEFF Research Database (Denmark)

    Fürst, F.; Grinberg, V.; Tomsick, J. A.

    2016-01-01

    We present an analysis of Nuclear Spectroscopic Telescope Array observations of a hard intermediate state of the transient black hole GX 339-4 taken in 2015 January. With the source softening significantly over the course of the 1.3 day long observation we split the data into 21 sub-sets and find...... that the spectrum of all of them can be well described by a power-law continuum with an additional relativistically blurred reflection component. The photon index increases from ∼1.69 to ∼1.77 over the course of the observation. The accretion disk is truncated at around nine gravitational radii in all spectra. We...

  17. Role of Glycolytic Intermediates in Global Regulation and Signal Transduction. Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Liao, J.C.

    2000-05-08

    The goal of this project is to determine the role of glycolytic intermediates in regulation of cell physiology. It is known that many glycolytic intermediates are involved in regulation of enzyme activities at the kinetic level. However, little is known regarding the role of these metabolites in global regulation and signal transduction. This project aims to investigate the role of glycolytic intermediates in the regulation of gene expression.

  18. Rising Billing for Intermediate Intensive Care among Hospitalized Medicare Beneficiaries between 1996 and 2010.

    Science.gov (United States)

    Sjoding, Michael W; Valley, Thomas S; Prescott, Hallie C; Wunsch, Hannah; Iwashyna, Theodore J; Cooke, Colin R

    2016-01-15

    Intermediate care (i.e., step-down or progressive care) is an alternative to the intensive care unit (ICU) for patients with moderate severity of illness. The adoption and current use of intermediate care is unknown. To characterize trends in intermediate care use among U.S. hospitals. We examined 135 million acute care hospitalizations among elderly individuals (≥65 yr) enrolled in fee-for-service Medicare (U.S. federal health insurance program) from 1996 to 2010. We identified patients receiving intermediate care as those with intensive care or coronary care room and board charges labeled intermediate ICU. In 1996, a total of 960 of the 3,425 hospitals providing critical care billed for intermediate care (28%), and this increased to 1,643 of 2,783 hospitals (59%) in 2010 (P billed for intermediate care, but billing steadily increased to 22.8% by 2010 (P billed for ICU care and ward-only care declined. Patients billed for intermediate care had more acute organ failures diagnoses codes compared with general ward patients (22.4% vs. 15.8%). When compared with patients billed for ICU care, those billed for intermediate care had fewer organ failures (22.4% vs. 43.4%), less mechanical ventilation (0.9% vs. 16.7%), lower mean Medicare spending ($8,514 vs. $18,150), and lower 30-day mortality (5.6% vs. 16.5%) (P billing increased markedly between 1996 and 2010. These findings highlight the need to better define the value, specific practices, and effective use of intermediate care for patients and hospitals.

  19. File list: Oth.PSC.20.AllAg.iPSC_intermediates [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.PSC.20.AllAg.iPSC_intermediates mm9 TFs and others Pluripotent stem cell iPSC intermediates...7379,SRX977371,SRX977370,SRX897943,SRX1184107,SRX897941 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/Oth.PSC.20.AllAg.iPSC_intermediates.bed ...

  20. File list: Oth.PSC.05.AllAg.iPSC_intermediates [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.PSC.05.AllAg.iPSC_intermediates mm9 TFs and others Pluripotent stem cell iPSC intermediates...7367,SRX977374,SRX897943,SRX977378,SRX1184107,SRX897941 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/Oth.PSC.05.AllAg.iPSC_intermediates.bed ...

  1. File list: Oth.PSC.10.AllAg.iPSC_intermediates [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.PSC.10.AllAg.iPSC_intermediates mm9 TFs and others Pluripotent stem cell iPSC intermediates...7378,SRX897943,SRX977370,SRX977371,SRX1184107,SRX897941 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/Oth.PSC.10.AllAg.iPSC_intermediates.bed ...

  2. File list: Oth.PSC.50.AllAg.iPSC_intermediates [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.PSC.50.AllAg.iPSC_intermediates mm9 TFs and others Pluripotent stem cell iPSC intermediates...7379,SRX977371,SRX977370,SRX897943,SRX897941,SRX1184107 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/Oth.PSC.50.AllAg.iPSC_intermediates.bed ...

  3. Asymptotically optimal production policies in dynamic stochastic jobshops with limited buffers

    Science.gov (United States)

    Hou, Yumei; Sethi, Suresh P.; Zhang, Hanqin; Zhang, Qing

    2006-05-01

    We consider a production planning problem for a jobshop with unreliable machines producing a number of products. There are upper and lower bounds on intermediate parts and an upper bound on finished parts. The machine capacities are modelled as finite state Markov chains. The objective is to choose the rate of production so as to minimize the total discounted cost of inventory and production. Finding an optimal control policy for this problem is difficult. Instead, we derive an asymptotic approximation by letting the rates of change of the machine states approach infinity. The asymptotic analysis leads to a limiting problem in which the stochastic machine capacities are replaced by their equilibrium mean capacities. The value function for the original problem is shown to converge to the value function of the limiting problem. The convergence rate of the value function together with the error estimate for the constructed asymptotic optimal production policies are established.

  4. Gulf-Wide Information System, Environmental Sensitivity Index Intermediate Marsh, Geographic NAD83, LDWF (2001) [esi_intermediate_marsh_LDWF_2001

    Data.gov (United States)

    Louisiana Geographic Information Center — This data set contains Environmental Sensitivity Index (ESI) intermediate marshes data of coastal Louisiana. The ESI is a classification and ranking system, which...

  5. Development and analysis of security policies in security enhanced Android

    OpenAIRE

    Rimando, Ryan A.

    2012-01-01

    Approved for public release; distribution is unlimited. This thesis examines Security Enhanced Android. Both its policy and its additional security features are explored. The policy is examined in depth, providing a better understanding of the security provided by SE Android. We analyze the default SE Android policy. We identify a potential weakness and change the policy to facilitate control over communication channels. A proof-of-concept set of applications is developed to demonstrate ho...

  6. Intermediates and Generic Convergence to Equilibria

    DEFF Research Database (Denmark)

    Marcondes de Freitas, Michael; Wiuf, Carsten; Feliu, Elisenda

    2017-01-01

    Known graphical conditions for the generic and global convergence to equilibria of the dynamical system arising from a reaction network are shown to be invariant under the so-called successive removal of intermediates, a systematic procedure to simplify the network, making the graphical conditions...

  7. Opening the Black Box of Intermediation

    DEFF Research Database (Denmark)

    Nowinska, Agnieszka

    This paper attempts to answer how external environmental factors affect intermediating firms within the maritime industry - the middlemen that plays a very important role in the sector. The category encompasses firms such as liner and port agencies, freight forwarders and shipbrokers, who link sh...

  8. Intermediate Filaments as Organizers of Cellular Space: How They Affect Mitochondrial Structure and Function.

    Science.gov (United States)

    Schwarz, Nicole; Leube, Rudolf E

    2016-07-05

    Intermediate filaments together with actin filaments and microtubules form the cytoskeleton, which is a complex and highly dynamic 3D network. Intermediate filaments are the major mechanical stress protectors but also affect cell growth, differentiation, signal transduction, and migration. Using intermediate filament-mitochondrial crosstalk as a prominent example, this review emphasizes the importance of intermediate filaments as crucial organizers of cytoplasmic space to support these functions. We summarize observations in different mammalian cell types which demonstrate how intermediate filaments influence mitochondrial morphology, subcellular localization, and function through direct and indirect interactions and how perturbations of these interactions may lead to human diseases.

  9. Exome sequencing identifies CTSK mutations in patients originally diagnosed as intermediate osteopetrosis.

    Science.gov (United States)

    Pangrazio, Alessandra; Puddu, Alessandro; Oppo, Manuela; Valentini, Maria; Zammataro, Luca; Vellodi, Ashok; Gener, Blanca; Llano-Rivas, Isabel; Raza, Jamal; Atta, Irum; Vezzoni, Paolo; Superti-Furga, Andrea; Villa, Anna; Sobacchi, Cristina

    2014-02-01

    Autosomal Recessive Osteopetrosis is a genetic disorder characterized by increased bone density due to lack of resorption by the osteoclasts. Genetic studies have widely unraveled the molecular basis of the most severe forms, while cases of intermediate severity are more difficult to characterize, probably because of a large heterogeneity. Here, we describe the use of exome sequencing in the molecular diagnosis of 2 siblings initially thought to be affected by "intermediate osteopetrosis", which identified a homozygous mutation in the CTSK gene. Prompted by this finding, we tested by Sanger sequencing 25 additional patients addressed to us for recessive osteopetrosis and found CTSK mutations in 4 of them. In retrospect, their clinical and radiographic features were found to be compatible with, but not typical for, Pycnodysostosis. We sought to identify modifier genes that might have played a role in the clinical manifestation of the disease in these patients, but our results were not informative. In conclusion, we underline the difficulties of differential diagnosis in some patients whose clinical appearance does not fit the classical malignant or benign picture and recommend that CTSK gene be included in the molecular diagnosis of high bone density conditions. Copyright © 2013 The Authors. Published by Elsevier Inc. All rights reserved.

  10. Technical Issues Associated With the Use of Intermediate Ethanol Blends (>E10) in the U.S. Legacy Fleet

    Energy Technology Data Exchange (ETDEWEB)

    Rich, Bechtold [Alliance Technical Services; Thomas, John F [ORNL; Huff, Shean P [ORNL; Szybist, James P [ORNL; West, Brian H [ORNL; Theiss, Timothy J [ORNL; Timbario, Tom [Alliance Technical Services; Goodman, Marc [Alliance Technical Services

    2007-08-01

    The Oak Ridge National Laboratory (ORNL) supports the U.S. Department of Energy (DOE) in assessing the impact of using intermediate ethanol blends (E10 to E30) in the legacy fleet of vehicles in the U.S. fleet. The purpose of this report is to: (1) identify the issues associated with intermediate ethanol blends with an emphasis on the end-use or vehicle impacts of increased ethanol levels; (2) assess the likely severity of the issues and whether they will become more severe with higher ethanol blend levels, or identify where the issue is most severe; (3) identify where gaps in knowledge exist and what might be required to fill those knowledge gaps; and (4) compile a current and complete bibliography of key references on intermediate ethanol blends. This effort is chiefly a critical review and assessment of available studies. Subject matter experts (authors and selected expert contacts) were consulted to help with interpretation and assessment. The scope of this report is limited to technical issues. Additional issues associated with consumer, vehicle manufacturer, and regulatory acceptance of ethanol blends greater than E10 are not considered. The key findings from this study are given.

  11. Policy Instruments for Sustainable Food Consumption

    DEFF Research Database (Denmark)

    Reisch, Lucia; Lorek, Sylvia; Bietz, Sabine

    The food policy domain highlights the complexity of the sustainability of food consumption. In addition to the ecological, social and economic aspects of food consumption, public health concerns are an integral factor in efforts to ensure the sustainable development of the food sector (Reisch et ...... with recommendations on actions that consumers (in their role as market actors and consumer citizens), NGOs, the media, the food industry, retailers and governments can take in a shared pursuit of more sustainable food consumption and production.......The food policy domain highlights the complexity of the sustainability of food consumption. In addition to the ecological, social and economic aspects of food consumption, public health concerns are an integral factor in efforts to ensure the sustainable development of the food sector (Reisch et al...... of the CORPUS project on sustainable food consumption. In general, governments trying to influence the sustainability of food systems have informationbased, market-based and regulatory instruments in their toolbox (Lorek et al., 2008). Their goal is to build a policy framework for appropriate action...

  12. Fission cross sections in the intermediate energy region

    International Nuclear Information System (INIS)

    Lisowski, P.W.; Gavron, A.; Parker, W.E.; Ullmann, J.L.; Balestrini, S.J.; Carlson, A.D.; Wasson, O.A.; Hill, N.W.

    1991-01-01

    Until recently there has been very little cross section data for neutron-induced fission in the intermediate energy region, primarily because no suitable neutron source has existed. At Los Alamos, the WNR target-4 facility provides a high-intensity source of neutrons nearly ideal for fission measurements extending from a fraction of a MeV to several hundred MeV. This paper summarizes the status of fission cross section data in the intermediate energy range (En > 30 MeV) and presents our fission cross section data for 235 U and 238 U compared to intranuclear cascade and statistical model predictions

  13. Fission cross sections in the intermediate energy region

    Energy Technology Data Exchange (ETDEWEB)

    Lisowski, P.W.; Gavron, A.; Parker, W.E.; Ullmann, J.L.; Balestrini, S.J. (Los Alamos National Lab., NM (USA)); Carlson, A.D.; Wasson, O.A. (National Inst. of Standards and Technology, Gaithersburg, MD (USA)); Hill, N.W. (Oak Ridge National Lab., TN (USA))

    1991-01-01

    Until recently there has been very little cross section data for neutron-induced fission in the intermediate energy region, primarily because no suitable neutron source has existed. At Los Alamos, the WNR target-4 facility provides a high-intensity source of neutrons nearly ideal for fission measurements extending from a fraction of a MeV to several hundred MeV. This paper summarizes the status of fission cross section data in the intermediate energy range (En > 30 MeV) and presents our fission cross section data for {sup 235}U and {sup 238}U compared to intranuclear cascade and statistical model predictions.

  14. Positron scattering by atomic hydrogen at intermediate energies

    International Nuclear Information System (INIS)

    Higgins, K.; Burke, P.G.; Walters, H.R.J.

    1990-01-01

    Results of an accurate calculation based upon the intermediate energy R-matrix theory are reported for elastic scattering of positrons by atomic hydrogen. T-matrix elements for both low and intermediate energy scattering are evaluated for the S e , P o , D e and F o partial wave symmetries. The low-energy elastic phaseshifts are found to be in good agreement with previous accurate variational calculations. Using an optical potential approach to include the effect of the higher partial waves, elastic and total cross sections are presented for energies ranging from near threshold to 3.7 Rydbergs. (author)

  15. File list: ALL.PSC.10.AllAg.iPSC_intermediates [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.PSC.10.AllAg.iPSC_intermediates mm9 All antigens Pluripotent stem cell iPSC intermediates...,SRX1178446,SRX1178449,SRX1178447,SRX897944,SRX1090865,SRX684777,SRX1090866 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/ALL.PSC.10.AllAg.iPSC_intermediates.bed ...

  16. Which visual functions depend on intermediate visual regions? Insights from a case of developmental visual form agnosia.

    Science.gov (United States)

    Gilaie-Dotan, Sharon

    2016-03-01

    A key question in visual neuroscience is the causal link between specific brain areas and perceptual functions; which regions are necessary for which visual functions? While the contribution of primary visual cortex and high-level visual regions to visual perception has been extensively investigated, the contribution of intermediate visual areas (e.g. V2/V3) to visual processes remains unclear. Here I review more than 20 visual functions (early, mid, and high-level) of LG, a developmental visual agnosic and prosopagnosic young adult, whose intermediate visual regions function in a significantly abnormal fashion as revealed through extensive fMRI and ERP investigations. While expectedly, some of LG's visual functions are significantly impaired, some of his visual functions are surprisingly normal (e.g. stereopsis, color, reading, biological motion). During the period of eight-year testing described here, LG trained on a perceptual learning paradigm that was successful in improving some but not all of his visual functions. Following LG's visual performance and taking into account additional findings in the field, I propose a framework for how different visual areas contribute to different visual functions, with an emphasis on intermediate visual regions. Thus, although rewiring and plasticity in the brain can occur during development to overcome and compensate for hindering developmental factors, LG's case seems to indicate that some visual functions are much less dependent on strict hierarchical flow than others, and can develop normally in spite of abnormal mid-level visual areas, thereby probably less dependent on intermediate visual regions. Copyright © 2015 Elsevier Ltd. All rights reserved.

  17. The policy relevance of global environmental change research

    International Nuclear Information System (INIS)

    Yarnal, Brent

    1996-01-01

    Many scientists are striving to identify and promote the policy implications of their global change research. Much basic research on global environmental change cannot advance policy directly, but new projects can determine the relevance of their research to decision makers and build policy-relevant products into the work. Similarly, many ongoing projects can alter or add to the present science design to make the research policy relevant. Thus, this paper shows scientists working on global change how to make their research policy relevant. It demonstrates how research on physical global change relates to human dimensions studies and integrated assessments. It also presents an example of how policy relevance can be fit retroactively into a global change project (in this case, SRBEX-the Susquehanna River Basin Experiment) and how that addition can enhance the project's status and science. The paper concludes that policy relevance is desirable from social and scientific perspectives

  18. Deep geologic repository for low and intermediate radioactive level waste in Canada

    International Nuclear Information System (INIS)

    Liu Jianqin; Li Honghui; Sun Qinghong; Yang Zhongtian

    2012-01-01

    Ontario Power Generation (OPG) is undergoing a project for the long-term management of low and intermediate level waste (LILW)-a deep geologic repository (DGR) project for low and intermediate level waste. The waste source term disposed, geologic setting, repository layout and operation, and safety assessment are discussed. It is expected to provide reference for disposal of low and intermediate level waste that contain the higher concentration of long-lived radionuclides in China. (authors)

  19. File list: ALL.PSC.50.AllAg.iPSC_intermediates [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.PSC.50.AllAg.iPSC_intermediates mm9 All antigens Pluripotent stem cell iPSC intermediates...44,SRX897944,SRX1178447,SRX684776,SRX684778,SRX684777,SRX1090865,SRX1090866 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/ALL.PSC.50.AllAg.iPSC_intermediates.bed ...

  20. File list: ALL.PSC.05.AllAg.iPSC_intermediates [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.PSC.05.AllAg.iPSC_intermediates mm9 All antigens Pluripotent stem cell iPSC intermediates...6,SRX1184108,SRX897944,SRX1178447,SRX684778,SRX684777,SRX1090865,SRX1090866 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/ALL.PSC.05.AllAg.iPSC_intermediates.bed ...

  1. File list: ALL.PSC.20.AllAg.iPSC_intermediates [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.PSC.20.AllAg.iPSC_intermediates mm9 All antigens Pluripotent stem cell iPSC intermediates...4,SRX1184108,SRX897944,SRX1178447,SRX684778,SRX1090865,SRX684777,SRX1090866 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/ALL.PSC.20.AllAg.iPSC_intermediates.bed ...

  2. Financial intermediation with credit constrained agents

    Czech Academy of Sciences Publication Activity Database

    Boháček, Radim

    2007-01-01

    Roč. 29, č. 4 (2007), s. 741-759 ISSN 0164-0704 R&D Projects: GA AV ČR IAA700850602 Institutional research plan: CEZ:AV0Z70850503 Keywords : financial intermediation * occupational choice * general equilibrium Subject RIV: AH - Economics Impact factor: 0.360, year: 2007

  3. Being back home after intermediate care

    DEFF Research Database (Denmark)

    Martinsen, Bente; Harder, Ingegerd; Norlyk, Annelise

    2015-01-01

    Older people may face many challenges and experience insecurity after discharge from hospital to home. To bridge the potential gap between general hospital and home, the concept ‘Intermediate Care’ (IC) was developed at the beginning of 2000. IC aims to safeguard older people from being discharge...

  4. CONSIDERATIONS REGARDING THE DEFINITION AND CLASSIFICATION OF COMMERCIAL INTERMEDIATION

    Directory of Open Access Journals (Sweden)

    DAN-ALEXANDRU SITARU

    2011-04-01

    Full Text Available The commercial intermediation is a complex juridical operation which includes a different number of juridical relationships that takes place between contractual partners either on a national or international level. These partners bare different naming due to their different set of rights and obligations set forth by the law or by the parties, and it is from this that the classification of the intermediation can be set forth. The commercial intermediation represents the activity that one person executes either in the name and on behalf of another person, or using its own name but on behalf of another person, or, finally, using its own name but on behalf of acting towards a common goal with the person who mandated her (the principal, in relation with who it is either a proxy or an independent intermediary, only negotiating or both negotiating and binding the principal. The purpose of the paper is to strictly define and set in order the various variations of the juridical operation that is the commercial intermediation, presented both in the light of the actual legal framework and also by reference to the New Civil Code. Also, the purpose is to highlight and systematize the contractual relationships from which the parties involved in a commercial intermediary operation may choose and the rights and obligations specific to each contract.

  5. Medical Advice for Sick-reported Students (MASS) in intermediate vocational education schools: design of a controlled before-and-after study.

    Science.gov (United States)

    Van der Vlis, Madelon K; Lugtenberg, Marjolein; Vanneste, Yvonne T M; Berends, Wenda; Mulder, Wico; Bannink, Rienke; Van Grieken, Amy; Raat, Hein; de Kroon, Marlou L A

    2017-06-29

    School absenteeism, including medical absenteeism, is associated with early school dropout and may result in physical, mental, social and work-related problems in later life. Especially at intermediate vocational education schools, high rates of medical absenteeism are found. In 2012 the Dutch intervention 'Medical Advice for Sick-reported Students' (MASS), previously developed for pre-vocational secondary education, was adjusted for intermediate vocational education schools. The aim of the study outlined in this paper is to evaluate the effectiveness of the MASS intervention at intermediate vocational education schools in terms of reducing students' medical absenteeism and early dropping out of school. Additionally, the extent to which biopsychosocial and other factors moderate the effectiveness of the intervention will be assessed. A controlled before-and-after study will be conducted within Intermediate Vocational Education schools. Schools are allocated to be an intervention or control school based on whether the schools have implemented the MASS intervention (intervention schools) or not (control schools). Intervention schools apply the MASS intervention consisting of active support for students with medical absenteeism provided by the school including a consultation with the Youth Health Care (YHC) professional if needed. Control schools provide care as usual. Data will be collected by questionnaires among students in both groups meeting the criteria for extensive medical absenteeism (i.e. 'reported sick four times in 12 school weeks or for more than six consecutive school days' at baseline and at 6 months follow-up). Additionally, in the intervention group a questionnaire is completed after each consultation with a YHC professional, by both the student and the YHC professional. Primary outcome measures are duration and cumulative incidence of absenteeism and academic performances. Secondary outcome measures are biopsychosocial outcomes of the students. It

  6. File list: NoD.PSC.05.AllAg.iPSC_intermediates [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available NoD.PSC.05.AllAg.iPSC_intermediates mm9 No description Pluripotent stem cell iPSC intermediates... http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/NoD.PSC.05.AllAg.iPSC_intermediates.bed ...

  7. File list: NoD.PSC.10.AllAg.iPSC_intermediates [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available NoD.PSC.10.AllAg.iPSC_intermediates mm9 No description Pluripotent stem cell iPSC intermediates... http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/NoD.PSC.10.AllAg.iPSC_intermediates.bed ...

  8. File list: NoD.PSC.20.AllAg.iPSC_intermediates [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available NoD.PSC.20.AllAg.iPSC_intermediates mm9 No description Pluripotent stem cell iPSC intermediates... http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/NoD.PSC.20.AllAg.iPSC_intermediates.bed ...

  9. File list: NoD.PSC.50.AllAg.iPSC_intermediates [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available NoD.PSC.50.AllAg.iPSC_intermediates mm9 No description Pluripotent stem cell iPSC intermediates... http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/NoD.PSC.50.AllAg.iPSC_intermediates.bed ...

  10. Intermediate phase evolution in YBCO thin films grown by the TFA process

    International Nuclear Information System (INIS)

    Zalamova, K; Pomar, A; Palau, A; Puig, T; Obradors, X

    2010-01-01

    The YBCO thin film growth process from TFA precursors involves a complex reaction path which includes several oxide, fluoride and oxyfluoride intermediate phases, and the final microstructure and properties of the films are strongly influenced by the morphological and chemical evolution of these intermediate phases. In this work we present a study of the evolution of the intermediate phases involved in the TFA YBCO growth process under normal pressure conditions and we show that the oxygen partial pressure during pyrolysis of the TFA precursors is an important parameter. The Cu phase after the TFA pyrolysis can be either CuO, Cu 2 O or a mixture of both as the oxygen partial pressure is modified. The kinetics evolution of the intermediate phases has been determined for films pyrolysed in oxygen and nitrogen atmospheres and it is concluded that non-equilibrium phase transformations influence the reaction path towards epitaxial YBCO films and its microstructure. The intermediate phase evolution in these two series of films is summarized in kinetic phase diagrams.

  11. V2487 Oph 1998: a post nova in an intermediate polar

    Directory of Open Access Journals (Sweden)

    Hernanz Margarita

    2014-01-01

    Full Text Available V2487 Oph (Nova Oph 1998 is a classical nova that exploded in 1998. XMM-Newton observations performed between 2 and 9 years after the explosion showed emission related to restablished accretion, and indicative of a magnetic white dwarf. The spectrum looks like that of a cataclysmic variable of the intermediate polar type. Anyway, we don’t have yet a definitive confirmation of the intermediate polar character, through determination of spin and orbital periods. Although it is not the first nova exploding in a magnetic white dwarf, it is always challenging to reach explosive conditions when a standard accretion disk can’t be formed, because of the magnetic field. In addition, V2487 Oph has been the first nova where a detection of X-rays - in the host binary system – has been reported prior to its eruption, in 1990 with the ROSAT satellite. V2487 Oph has been also detected in hard X-rays with INTEGRAL/IBIS and RXTE/PCA. Last but not least, V2487 Oph has been identified as a recurrent nova in 2008, since a prior eruption in 1900 has been reported through analysis of Harvard photographic plates. Therefore, it is expected to host a massive white dwarf and be a candidate for a type Ia supernova explosion. In a recent study of the progenitors of galactic novae, it has been emphasized that V2487 Oph is an important and interesting object, "intermediate" between the "standard" classical novae and other historical and well-known recurrent novae with shorter recurrence periods. It could be that in the end there’s a continuous distribution of recurrence periods, instead of the common understanding up to now that "classical" and "recurrent" novae were quite apart (with recurrence periods of more than 104 years and less than 100years - approximately - respectively. We present the results of our campaign of several observations with XMM-Newton. The consequences for the understanding of such a puzzling object are discussed.

  12. 48 CFR 928.101-1 - Policy on use.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Policy on use. 928.101-1... REQUIREMENTS BONDS AND INSURANCE Bonds and Other Financial Protections 928.101-1 Policy on use. In addition to... for fixed price or unit price contracts entered into as a result of sealed bidding. They may not be...

  13. Determination of Intermediate Resonance Parameter with RMET21 for nTRACER

    International Nuclear Information System (INIS)

    Sohail, Muhammad; Kim, Myung Hyun

    2012-01-01

    Ray Tracing based code nTRACER is being developed in Seoul National University that has the capability of 3-dimensional whole core neutron transport calculation. As a part of development of multi-group neutron cross section library for nTRACER, the current work is intended to accurately determine intermediate resonance parameters. Beside the systematic calculation of subgroup parameters for resonance self shielding calculation, intermediate resonance parameters itself can be as important as the multi-group neutron cross section in the library and its overall accuracy. In this paper lambda factors were computed using RMET21 from ENDF/B-VII.1 for nTRACER to investigate its dependence on temperature and background cross section and replaced with lambda factors from HELIOS multi-group library. The procedure used for determining the intermediate resonance parameter for the isotope under study is introduced in the next section. Oxygen being one of the primary nuclide in PWR fuel has been selected for intermediate resonance parameters calculation

  14. Role of interference of states of intermediate nuclei in exchange processes

    International Nuclear Information System (INIS)

    Belyaeva, T.L.; Zelenskaya, N.S.; Teplov, I.B.

    1982-01-01

    Role of interference of intermediate nucleus states for exchange processes in reactions with alpha particles on 11 B, 7 Li and 6 Li light nuclei was investigated when considering exactly the process dynamics in the method of distorted waves with a finite interaction radius. The process dynamics, in particular, the overlapping degree of wave functions of bound states and interaction potentials, affects considerably the reaction cross section in the rections with alpha particles on nuclei of 1p shell. If in the reaction selection rules permit the excitation of components of intermediate system states with maximum values of #betta# 1 and #betta# 2 orbital moments at the given N 1 and N 2 , the contribution of such components to the cross section will be determining. When components of intermediate system states with maximum #betta# 1 (or #betta# 2 ) are forbidden with selection rules, several intermediate states can have approximately similar overlapping integrals

  15. Examining moral thinking of adolescents through intermediate concepts

    Directory of Open Access Journals (Sweden)

    Frichand Ana

    2011-01-01

    Full Text Available This study examines moral thinking of adolescents through intermediate concepts. Intermediate concepts describe a level of analysis that falls between the general default schemas defined in Kohlberg's theory and specific ethical codes. They are related to the ability to identify good and bad actions and justifications in solving specific moral dilemmas. Participants were adolescent males and females in early, middle and late adolescence. The type of education, expressed antisocial behaviour and the primary group of socialization (family were analyzed as well. The results indicate that the ability to identify good and bad actions and justifications is increasing with age. Female adolescents have higher scores on this ability than male adolescents. Individuals in late adolescence, who are concentrating more on moral values and principles during education, show higher ability in identifying bad actions and justifications. In middle adolescence those who exhibit antisocial behaviour have lower ability in identifying intermediate concepts, compared to their peers who do not show this type of behaviour. Similar results are true for those living in institutions for children without parents and parental care when compared to adolescents who are living with their parents. .

  16. The impact of intermediate care services on job satisfaction, skills and career development opportunities.

    Science.gov (United States)

    Nancarrow, Susan

    2007-07-01

    The purpose of this study was to examine, in depth, the impact of intermediate care services on staff job satisfaction, skills development and career development opportunities. Recruitment and retention difficulties present a major barrier to the effective delivery of intermediate care services in the UK. The limited existing literature is contradictory, but points to the possibility of staff deskilling and suggests that intermediate care is poorly understood and may be seen by other practitioners as being of lower status than hospital work. These factors have the potential to reduce staff morale and limit the possibilities of recruiting staff. The research is based on interviews with 26 staff from case studies of two intermediate care services in South Yorkshire. Participants reported high levels of job satisfaction, which was because of the enabling philosophy of care, increased autonomy, the setting of care and the actual teams within which the workers were employed. For most disciplines, intermediate care facilitated the application of existing skills in a different way; enhancing some skills, while restricting the use of others. Barriers to career development opportunities were attributed to the relative recency of intermediate care services, small size of the services and lack of clear career structures. Career development opportunities in intermediate care could be improved through staff rotations through acute, community and intermediate care to increase their awareness of the roles of intermediate care staff. The non-hierarchical management structures limits management career development opportunities, instead, there is a need to enhance professional growth opportunities through the use of consultant posts and specialization within intermediate care. This study provides insight into the impact of an increasingly popular model of care on the roles and job satisfaction of workers and highlights the importance of this learning for recruitment and retention of

  17. Use of low density lipoprotein particle number levels as an aid in statin treatment decisions for intermediate risk patients: a cost-effectiveness analysis.

    Science.gov (United States)

    Shiffman, Dov; Arellano, Andre R; Caulfield, Michael P; Louie, Judy Z; Bare, Lance A; Devlin, James J; Melander, Olle

    2016-12-07

    The 2013 ACC/AHA guideline recommended either no statin therapy or moderate-intensity statin therapy (MST) for intermediate risk patients-those with 5-7.5% 10-year risk and without cardiovascular disease (CVD), hypercholesterolemia or diabetes. The guideline further suggested that the therapy choice be based on patient-clinician discussions of risks and benefits. Since low-density lipoprotein particle (LDL-P) levels were reported to be associated with CVD independently of traditional risk factors in intermediate and low risk patients, we investigated the cost-effectiveness of using LDL-P levels to identify intermediate risk patients likely to benefit from initiating or intensifying statin therapy. We evaluated 5 care strategies for intermediate risk patients. These included the strategies suggested by the guideline: no-statin therapy and MST. We compared each of these strategies to a related strategy that incorporated LDL-P testing. No-statin therapy was compared with the strategy of MST for those with high LDL-P levels and no statin therapy for all other patients (test-and-MST). MST was compared with the strategy of high-intensity statin therapy (HST) for those with high LDL-P levels and MST for all other patients (test-and-HST). We also evaluated the strategy of HST for all. Costs (payer perspective) and utilities were assessed over a 5-year time horizon in a Markov model of 100,000 hypothetical intermediate risk patients. HST dominated all other strategies, costing less and-despite causing 739 more cases of diabetes than did MST-resulting in more quality adjusted life-years (QALYs). For patient-clinician discussions that would otherwise lead to the MST strategy, we found the test-and-HST strategy reduced costs by $4.67 MM and resulted in 134 fewer CVD events and 115 additional QALYs. For patient-clinician discussions that would otherwise lead to no statin therapy, we found that the test-and-MST strategy reduced costs by $3.25 MM, resulted in 97 fewer CVD events

  18. Historical and idealized climate model experiments: an intercomparison of Earth system models of intermediate complexity

    DEFF Research Database (Denmark)

    Eby, M.; Weaver, A. J.; Alexander, K.

    2013-01-01

    Both historical and idealized climate model experiments are performed with a variety of Earth system models of intermediate complexity (EMICs) as part of a community contribution to the Intergovernmental Panel on Climate Change Fifth Assessment Report. Historical simulations start at 850 CE...... and continue through to 2005. The standard simulations include changes in forcing from solar luminosity, Earth's orbital configuration, CO2, additional greenhouse gases, land use, and sulphate and volcanic aerosols. In spite of very different modelled pre-industrial global surface air temperatures, overall 20...

  19. PNGMDR - Characterisation of intermediate-level long-lived wastes

    International Nuclear Information System (INIS)

    2014-12-01

    This document presents the status of the characterization of intermediate-level long-lived wastes which are warehoused on exploited EDF sites or which will be produced during the deconstruction of first-generation reactors. It addresses aspects related to characterisation and packaging of wastes produced before 2015. More specifically, it addresses aspects related to contamination and to activation. Contamination is assessed by measurements whereas activation assessment is based on numerical simulations associated with measurements performed during parcel production. After having mentioned the concerned reactors, the document presents the methodology adopted for these assessments, and reports the progress status of the characterization process for these intermediate-level long-lived wastes

  20. New staff contract policy

    CERN Document Server

    HR Department

    2006-01-01

    Following discussion at TREF and on the recommendation of the Finance Committee, Council approved a new staff contract policy, which became effective on 1 January 2006. Its application is covered by a new Administrative Circular No. 2 (Rev. 3) 'Recruitment, appointment and possible developments regarding the contractual position of staff members'. The revised circular replaces the previous Circulars No. 9 (Rev. 3) 'Staff contracts' and No. 2 (Rev. 2) 'Guidelines and procedures concerning recruitment and probation period for staff members'. The main features of the new contract policy are as follows: The new policy provides chances for long-term employment for all staff recruits staying for four years without distinguishing between those assigned to long-term or short-term activities when joining CERN. In addition, it presents a number of simplifications for the award of ICs. There are henceforth only 2 types of contract: Limited Duration (LD) contracts for all recruitment and Indefinite Contracts (IC) for...

  1. How Do Transfer Students Perform in Economics? Evidence from Intermediate Macroeconomics

    Science.gov (United States)

    Asarta, Carlos J.; Fuess, Scott M., Jr.; Perumal, Andrew

    2013-01-01

    For students taking intermediate-level economics, does it matter where they studied principles of economics? Does transferring college credit influence subsequent academic performance in economics? With a sample covering 1999-2008, the authors analyze in this article a group of nearly 1,000 students taking intermediate macroeconomics at a…

  2. C and C* among intermediate rings

    NARCIS (Netherlands)

    Sack, J.; Watson, S.

    2014-01-01

    Given a completely regular Hausdorff space X, an intermediate ring A(X) is a ring of real valued continuous functions between C*(X) and C(X). We discuss two correspondences between ideals in A(X) and z-filters on X, both reviewing old results and introducing new results. One correspondence, ZA,

  3. 45 CFR 287.60 - Are there additional financial reporting and auditing requirements?

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Are there additional financial reporting and... there additional financial reporting and auditing requirements? (a) The reporting of expenditures are... comply with all laws, regulations, and Departmental policies that govern submission of financial reports...

  4. Intermediate Temperature Fuel Cell Using Gypsum Based Electrolyte And Electrodes

    International Nuclear Information System (INIS)

    Suzuki, Satoshi; Nagai, Masayuki; Katagiri, Yuji

    2011-01-01

    The proton conductive electrolyte membrane and the electrodes for intermediate temperature fuel cell were made from the phosphoric acid treated gypsum as a proton conductor. The membrane and the electrodes were built into single cell and tested at intermediate temperature region. The power density of the fuel cell was 0.56 mW/cm -2 at 150 deg. C without any humidification and 1.38 mW/cm -2 at 150 deg. C, 5% relative humidity. The open circuit voltage of the cell was increased higher than 0.7 V when the electrodes were annealed at 150 deg. C, 5%R.H., however the reasons for this are still to be further investigated. The results show that the potential of the phosphoric acid treated gypsum for the intermediate temperature proton conductor.

  5. Social values and solar energy policy: the policy maker and the advocate

    Energy Technology Data Exchange (ETDEWEB)

    Shama, A.; Jacobs, K.

    1980-07-01

    Solar energy policy makers and advocates have significantly different hierarchies (clusters) of values upon which they evaluate the adoption of solar technologies. Content analysis, which examines the frequency with which policy makers identify different types of values, indicates that they hold economic values to be of primary importance. Environmental, social, and national security values are also substantial elements of the policy makers' value clusters associated with solar energy. This finding is confirmed by a qualitative analysis of policy makers' values. Advocates, on the other hand, assign almost equal weights (33%) to economic values and social values, slightly less weight to environmental values, and significant attention to ethical and security values as well. These results of frequency analysis are made somewhat more complicated by a qualitative interpretation of the advocates' positions. As part of their more holistic approach, several of the advocates indicated that all values discussed by them are instrumental toward achieving higher-order, ethical and environmental values. In addition, our preliminary investigation indicates that neither group is entirely homogeneous. Testing this and other propositions, as well as obtaining a similar picture of the values which the public associates with solar energy, are topics of future research.

  6. On intermediate structures in heavy ion reactions

    International Nuclear Information System (INIS)

    Rotter, I.

    1977-01-01

    The conceptions of the nuclear reaction theory are reinvestigated on the basis of the continuum shell model. The correlation of the resonance states via the continuum can lead to intermediate structures in the cross section. (Auth.)

  7. Smoke-free air policies: past, present and future.

    Science.gov (United States)

    Hyland, Andrew; Barnoya, Joaquin; Corral, Juan E

    2012-03-01

    Smoke-free policies have been an important tobacco control intervention. As recently as 20 years ago, few communities required workplaces and hospitality venues to be smoke-free, but today approximately 11% of the world's population live in countries with laws that require these places to be smoke-free. This paper briefly summarises important milestones in the history of indoor smoke-free policies, the role of scientific research in facilitating their adoption, a framework for smoke-free policy evaluation and industry efforts to undermine regulations. At present, smoke-free policies centre on workplaces, restaurants and pubs. In addition, many jurisdictions are now beginning to implement policies in outdoor areas and in shared multiunit housing settings. The future of smoke-free policy development depends on credible scientific data that documents the health risks of secondhand smoke exposure. Over the next 20 years smoke-free policies will very likely extend to outdoor and private areas, and changes in the types of tobacco products that are consumed may also have implications for the nature and scope of the smoke-free policies of the future.

  8. Alternatives generation and analysis for phase I intermediate waste feed staging system design requirements

    Energy Technology Data Exchange (ETDEWEB)

    Britton, M.D.

    1996-10-02

    This document provides; a decision analysis summary; problem statement; constraints, requirements, and assumptions; decision criteria; intermediate waste feed staging system options and alternatives generation and screening; intermediate waste feed staging system design concepts; intermediate waste feed staging system alternative evaluation and analysis; and open issues and actions.

  9. Synthesis of a Fluorescent Acridone Using a Grignard Addition, Oxidation, and Nucleophilic Aromatic Substitution Reaction Sequence

    Science.gov (United States)

    Goodrich, Samuel; Patel, Miloni; Woydziak, Zachary R.

    2015-01-01

    A three-pot synthesis oriented for an undergraduate organic chemistry laboratory was developed to construct a fluorescent acridone molecule. This laboratory experiment utilizes Grignard addition to an aldehyde, alcohol oxidation, and iterative nucleophilic aromatic substitution steps to produce the final product. Each of the intermediates and the…

  10. Greenhouse gas emissions trading and complementary policies. Developing a smart mix for ambitious climate policies

    Energy Technology Data Exchange (ETDEWEB)

    Matthes, Felix C.

    2010-06-15

    A debate has - most notably as a result of the introduction of fixed caps within the framework of emissions trading - been raised about the need for using additional instruments of climate and energy policy. A common line of argument is that the targets set within the emissions trading scheme are going to be met with a high degree of certainty, and flexibility among the regulated stakeholders will lead to market-based discovery processes. Additional instruments would only generate additional costs and would therefore have to be rejected. However, closer analysis of these fundamental arguments shows that they are constructed on a very high level of abstraction and sometimes rely on strongly simplifying or idealising assumptions. Their theoretical assumptions are, at least in part, very questionable and do not correspond to conditions in the real world for climate and energy policy. At the same time the debate about policy instruments cannot be held autonomously of the specific context of the problem at hand. In this sense the very extensive (complete) and above all effective decarbonisation of the economies of industrialised countries in a comparatively short time frame is the key basic condition for the analysis, assessment and design of the climate policy mix. Essentially, the question is what the best instruments are for purging the whole economic system almost entirely of CO{sub 2} emissions within a period of only forty years. The introduction of emissions trading schemes for greenhouse gases in an increasing number of OECD countries undoubtedly constitutes an important landmark of climate policy. They: - provide a high degree of certainty in terms of meeting targets; - create, on the basis of a standardised price signal, a clearing mechanism for the broad spectrum of emission reduction options close to the market, at least in the short to medium term; and - represent, by means of linking, an interesting option in terms of the globalisation of climate policy

  11. 17 CFR 229.1011 - (Item 1011) Additional information.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false (Item 1011) Additional information. 229.1011 Section 229.1011 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION STANDARD INSTRUCTIONS FOR FILING FORMS UNDER SECURITIES ACT OF 1933, SECURITIES EXCHANGE ACT OF 1934 AND ENERGY POLICY AND CONSERVATION ACT OF 1975...

  12. Elections and landmark policies in Tanzania and Uganda

    DEFF Research Database (Denmark)

    Kjær, Anne Mette; Therkildsen, Ole

    2013-01-01

    Much of the relevant literature on Africa downplays the salience of elections for policy-making and implementation. Instead, the importance of factors such as clientelism, ethnicity, organized interest group and donor influence, is emphasized. We argue that, in addition, elections now motivate...... political elites to focus on policies they perceive to be able to gain votes. This is based on analyses of six landmark decisions made during the last fifteen years in the social, productive and public finance sectors in Tanzania and Uganda. Such policies share a number of key characteristics......: they are clearly identifiable with the party in power; citizens country-wide are targeted; and policy implementation aim at immediate, visible results. The influence of elections on policy making and implementation could therefore be more significant in countries where elections are more competitive than...

  13. Software Testing An ISEB Intermediate Certificate

    CERN Document Server

    Hambling, Brian

    2009-01-01

    Covering testing fundamentals, reviews, testing and risk, test management and test analysis, this book helps newly qualified software testers to learn the skills and techniques to take them to the next level. Written by leading authors in the field, this is the only official textbook of the ISEB Intermediate Certificate in Software Testing.

  14. Arctic Intermediate Water in the Nordic Seas, 1991-2009

    Science.gov (United States)

    Jeansson, Emil; Olsen, Are; Jutterström, Sara

    2017-10-01

    The evolution of the different types of Arctic Intermediate Water (AIW) in the Nordic Seas is evaluated and compared utilising hydro-chemical data from 1991 to 2009. It has been suggested that these waters are important components of the Norwegian Sea Arctic Intermediate Water (NSAIW), and of the dense overflows to the North Atlantic. Thus, it is important to understand how their properties and distribution vary with time. The AIWs from the Greenland and Iceland Seas, show different degrees of variability during the studied period; however, only the Greenland Sea Arctic Intermediate Water (GSAIW) shows an increasing temperature and salinity throughout the 2000s, which considerably changed the properties of this water mass. Optimum multiparameter (OMP) analysis was conducted to assess the sources of the NSAIW. The analysis shows that the Iceland Sea Arctic Intermediate Water (ISAIW) and the GSAIW both contribute to NSAIW, at different densities corresponding to their respective density range. This illustrates that they flow largely isopycnally from their source regions to the Norwegian Sea. The main source of the NSAIW, however, is the upper Polar Deep Water, which explains the lower concentrations of oxygen and chlorofluorocarbons, and higher salinity and nutrient concentrations of the NSAIW layer compared with the ISAIW and GSAIW. This shows how vital it is to include chemical tracers in any water mass analysis to correctly assess the sources of the water mass being studied.

  15. Financial stability and monetary policy -The case of Brazil

    Directory of Open Access Journals (Sweden)

    Benjamin M. Tabak

    2013-12-01

    Full Text Available This paper seeks to examine the effects of monetary policy over banks' loans growth and whether there is a bank lending channel operating in Brazil. Therefore, we employ a detailed high frequency panel data in which we include bank characteristics and ownership control. We contribute to the literature on bank lending channel by showing that during periods of loosening/tightening monetary policy, banks increase/decrease their loans. Additionally,our results illustrate that large, well-capitalized and liquid banks react differentially to the effects of monetary policy shocks. Finally, we show that the impact of monetary policy differs across state-owned, foreign and private domestic banks. These results are important for developing and conducting monetary policy.

  16. Improving hospital discharge arrangements for people who are homeless: A realist synthesis of the intermediate care literature.

    Science.gov (United States)

    Cornes, Michelle; Whiteford, Martin; Manthorpe, Jill; Neale, Joanne; Byng, Richard; Hewett, Nigel; Clark, Michael; Kilmister, Alan; Fuller, James; Aldridge, Robert; Tinelli, Michela

    2018-05-01

    This review presents a realist synthesis of "what works and why" in intermediate care for people who are homeless. The overall aim was to update an earlier synthesis of intermediate care by capturing new evidence from a recent UK government funding initiative (the "Homeless Hospital Discharge Fund"). The initiative made resources available to the charitable sector to enable partnership working with the National Health Service (NHS) in order to improve hospital discharge arrangements for people who are homeless. The synthesis adopted the RAMESES guidelines and reporting standards. Electronic searches were carried out for peer-reviewed articles published in English from 2000 to 2016. Local evaluations and the grey literature were also included. The inclusion criteria was that articles and reports should describe "interventions" that encompassed most of the key characteristics of intermediate care as previously defined in the academic literature. Searches yielded 47 articles and reports. Most of these originated in the UK or the USA and fell within the realist quality rating of "thick description". The synthesis involved using this new evidence to interrogate the utility of earlier programme theories. Overall, the results confirmed the importance of (i) collaborative care planning, (ii) reablement and (iii) integrated working as key to effective intermediate care delivery. However, the additional evidence drawn from the field of homelessness highlighted the potential for some theory refinements. First, that "psychologically informed" approaches to relationship building may be necessary to ensure that service users are meaningfully engaged in collaborative care planning and second, that integrated working could be managed differently so that people are not "handed over" at the point at which the intermediate care episode ends. This was theorised as key to ensuring that ongoing care arrangements do not break down and that gains are not lost to the person or the system

  17. Global Status Report on Local Renewable Energy Policies

    International Nuclear Information System (INIS)

    Martinot, Eric; Yamashita, Noriaki; Tan, Vincent; Irie, Risa; Van Staden, Maryke; Zimmermann, Monika

    2011-01-01

    This report complements the REN21 Renewables Global Status Report by providing more detailed information at the city and local levels about policies and activities to promote renewable energy. It is intended to facilitate dialogue and illuminate pathways for future policies and actions at the local level. This 'working draft' version is intended to solicit comments and additional information

  18. Environmental Policy and Technological Change

    International Nuclear Information System (INIS)

    Jaffe, Adam B.; Newell, Richard G.; Stavins, Robert N.

    2002-01-01

    The relationship between technological change and environmental policy has received increasing attention from scholars and policy makers alike over the past ten years. This is partly because the environmental impacts of social activity are significantly affected by technological change, and partly because environmental policy interventions themselves create new constraints and incentives that affect the process of technological developments. Our central purpose in this article is to provide environmental economists with a useful guide to research on technological change and the analytical tools that can be used to explore further the interaction between technology and the environment. In Part 1 of the article, we provide an overview of analytical frameworks for investigating the economics of technological change, highlighting key issues for the researcher. In Part 2, we turn our attention to theoretical analysis of the effects of environmental policy on technological change, and in Part 3, we focus on issues related to the empirical analysis of technology innovation and diffusion. Finally, we conclude in Part 4 with some additional suggestions for research

  19. Photo-induced bleaching of sensory rhodopsin II (phoborhodopsin) from Halobacterium salinarum by hydroxylamine: identification of the responsible intermediates.

    Science.gov (United States)

    Tamogami, Jun; Kikukawa, Takashi; Ikeda, Yoichi; Demura, Makoto; Nara, Toshifumi; Kamo, Naoki

    2012-01-05

    Sensory rhodopsin II from Halobacterium salinarum (HsSRII) is a retinal protein in which retinal binds to a specific lysine residue through a Schiff base. Here, we investigated the photobleaching of HsSRII in the presence of hydroxylamine. For identification of intermediate(s) attacked by hydroxylamine, we employed the flash-induced bleaching method. In order to change the concentration of intermediates, such as M- and O-intermediates, experiments were performed under varying flashlight intensities and concentrations of azide that accelerated only the M-decay. We found the proportional relationship between the bleaching rate and area under the concentration-time curve of M, indicating a preferential attack of hydroxylamine on M. Since hydroxylamine is a water-soluble reagent, we hypothesize that for M, hydrophilicity or water-accessibility increases specifically in the moiety of Schiff base. Thus, hydroxylamine bleaching rates may be an indication of conformational changes near the Schiff base. We also considered the possibility that azide may induce a small conformational change around the Schiff base. We compared the hydroxylamine susceptibility between HsSRII and NpSRII (SRII from Natronomonas pharaonis) and found that the M of HsSRII is about three times more susceptible than that of the stable NpSRII. In addition, long illumination to HsSRII easily produced M-like photoproduct, P370. We thus infer that the instability of HsSRII under illumination may be related to this increase of hydrophilicity at M and P370. Copyright © 2011 Elsevier B.V. All rights reserved.

  20. A population growth trend analysis for Neotricula aperta, the snail intermediate host of Schistosoma mekongi, after construction of the Pak-Mun dam.

    Directory of Open Access Journals (Sweden)

    Stephen W Attwood

    2013-11-01

    Full Text Available The Pak-Mun dam is a controversial hydro-power project on the Mun River in Northeast Thailand. The dam is sited in a habitat of the freshwater snail Neotricula aperta, which is the intermediate host for the parasitic blood-fluke Schistosoma mekongi causing Mekong schistosomiasis in humans in Cambodia and Laos. Few data are available which can be used to assess the effects of water resource development on N. aperta. The aim of this study was to obtain data and to analyze the possible impact of the dam on N. aperta population growth.Estimated population densities were recorded for an N. aperta population in the Mun River 27 km upstream of Pak-Mun, from 1990 to 2011. The Pak-Mul dam began to operate in 1994. Population growth was modeled using a linear mixed model expression of a modified Gompertz stochastic state-space exponential growth model. The N. aperta population was found to be quite stable, with the estimated growth parameter not significantly different from zero. Nevertheless, some marked changes in snail population density were observed which were coincident with changes in dam operation policy.The study found that there has been no marked increase in N. aperta population growth following operation of the Pak-Mun dam. The analysis did indicate a large and statistically significant increase in population density immediately after the dam came into operation; however, this increase was not persistent. The study has provided the first vital baseline data on N. aperta population behavior near to the Pak-Mun dam and suggests that the operation policy of the dam may have an impact on snail population density. Nevertheless, additional studies are required for other N. aperta populations in the Mun River and for an extended time series, to confirm or refine the findings of this work.

  1. Reactive intermediates in the gas phase generation and monitoring

    CERN Document Server

    Setser, D W

    2013-01-01

    Reactive Intermediates in the Gas Phase: Generation and Monitoring covers methods for reactive intermediates in the gas phase. The book discusses the generation and measurement of atom and radical concentrations in flow systems; the high temperature flow tubes, generation and measurement of refractory species; and the electronically excited long-lived states of atoms and diatomic molecules in flow systems. The text also describes the production and detection of reactive species with lasers in static systems; the production of small positive ions in a mass spectrometer; and the discharge-excite

  2. A review on global wind energy policy

    International Nuclear Information System (INIS)

    Saidur, R.; Islam, M.R.; Rahim, N.A.; Solangi, K.H.

    2010-01-01

    With the increasing negative effects of fossil fuel combustion on the environment in addition to limited stock of fossil fuel have forced many countries to inquire into and change to environmentally friendly alternatives that are renewable to sustain the increasing energy demand. Energy policy plays a vital role to mitigate the impacts of global warming and crisis of energy availability. This paper explores the wind energy industry from the point of view of the wind energy policy. It is noticed that energy policy could help increasing wind power generation as well as stimulating the energy industry. It may be stated that without specific energy policy, a country would not be able to solve the acute problems like reducing greenhouse gases (GHGs) emission, scarcity of energy, etc. This paper discussed the existing successful energy policies for few selected countries. Based on literatures, it has been found that FIT, RPS, incentives, pricing law and Quota system are the most useful energy policies practiced by many countries around the world. Then, status of wind energy policy for Malaysia was investigated and compared with few selected countries around the world. (author)

  3. Review of intermediate and final product characterization on coated particles preparation

    International Nuclear Information System (INIS)

    Sukarsono; Kristanti Nurwidyaningrum

    2015-01-01

    Review of the intermediate and final product characterization on preparation of coated particles was done. Product characterization included a tool to measure the character of raw materials, intermediate product and the final product of the process, which affects the success of getting the high temperature reactor fuel are eligible. Equipment's for the characterization of such materials were pH meter, viscometer, microbalance, turbidity meter, tab density measurement, true density measurement and auto pycnometer. Being for the measurement of particles there are two types destructive testing and non destructive. Destructive testing was done by polished the particles then cross sectional imaging of particle observed using an optical microscope. In this way contains errors due to polishing treatment that could not be right on the equator section so it needs correction. Destructive testing also create waste that must be processed from the remnants of the polishing process. By using non-destructive testing, waste was not formed but the imaging results are often unclear due to lack of contrast. Development of non-destructive test equipment has been made using radiographic method and automated microscopy. The overall activity is still much needed additional tools for measurement and for processing, so that the results obtained will not rejected as the specification of nuclear fuel. Similarly, in the case of a sampling test method and limits to a product accepted or rejected, it should be determined based on statistical methods. (author)

  4. Stingray-inspired robot with simply actuated intermediate motion

    Science.gov (United States)

    Neely, Lincoln; Gaiennie, Jack; Noble, Nick; Erickson, Jonathan C.

    2016-04-01

    Batoids, or rays, utilize unique forms of locomotion that may offer more efficient techniques of motorized propulsion in various marine environments. We present a novel biomimetic engineering design and assembly of a stingray-inspired robot swimmer. The robots locomotion mimics the Dasyatis americana, or southern stingray, whose distinction among rays is its intermediate motion, characterized by sweeping strokes that propagate between 1/2-1 wavelength of the fin profile in the posterior direction. Though oscillatory ( wavelengths) ray-based robots have been created, this project demonstrates new engineering possibilities in what is, to the best of our knowledge, the first intermediately propelled batoid-based robot. The robots fins were made of silicone rubber, cast in a 3-D printed mold, with wingspan of 42 cm (1/2 - 1/5 scale for males and females, respectively, scale of model organism). Two anteriorly placed servomotors per fin were used, all controlled by one wirelessly enabled Arduino microcontroller. Each servomotor oscillated a flexible rod with cylindrical joint, whose frequency, speed, and front-back phase delay were user-programmed over wireless connection. During free-swimming tests, the fin profile developed about 0.8 wavelength, qualifying for successful mimicry of its biological inspiration. The robot satisfactorily maintained straight-line motion, reaching average peak velocity of 9.4+/-1.0 cm/s (0.27-0.03 body lengths/second) at its optimum flapping frequency of 1.4 Hz. This is in the same order of magnitude of speed normalized to body length achieved by others in two recent batoid-based projects. In summary, our robot performed intermediate stingray locomotion with relatively fewer components, which reveals robust potential for innovation of the simple intermediate batoid-based robot swimmer.

  5. Analysis and solution of spike current of intermediate range for nuclear instrumentation system

    International Nuclear Information System (INIS)

    Li Xingqiang; Xiao Yu; Xue Bin; Wang Yinli

    2015-01-01

    During the initial start-up of HYH NPP unit 1, spike currents occurred in intermediate range channel of RPN system and reactor trip was triggered. After analyzing the operation principle of intermediate range channel and site inspection, and doing simulating test, the root cause was fixed on the bug of range switching of intermediate range channel. Then a solution based on parameters optimizing was made and executed on site. (authors)

  6. Connecting demand and supply: The role of intermediation in public procurement of innovation

    OpenAIRE

    Yeow, Jillian; Edler, Jakob

    2015-01-01

    open access article Intermediation in innovation serves to establish or improve the link between different actors with complementary skill sets or interests in order to support the generation and diffusion of innovation. This article conceptualises and analyses intermediation between supply and demand using the example of public procurement of innovation. It defines specific intermediation needs and functions in different procurement situations and outlines the pre-condition for effective ...

  7. Policy for returning to fisheries in Korea

    Directory of Open Access Journals (Sweden)

    Jihoon Kim

    2016-07-01

    Full Text Available Korea’s fishing industry is currently facing problems involving an aging society and lack of successors in fishing villages. Therefore, the Korea Ministry of Oceans and Fisheries (KMOF has implemented a policy supporting U-turn fishers, who leave their place of origin for a job and then return home or move to where they can work in the fishing industry. Moreover, some local governments have established a policy for U-turn fishers. The KMOF policy is a financial support program with low interest rates and lengthy reimbursement periods; however, few beneficiaries exist. Meanwhile, local government policy benefits most persons in corresponding areas. However, the sums are relatively small, and only two local governments have enacted the policy. This study determines the performance of the policy through indepth interviews and a survey. The results indicate that KMOF policy may be limited in terms of its scope. In addition, noneconomic support programs, such as fishing education, harmony between existing fishers, and the acquisition of fishery rights, are required. The number of U-turn fishers will continue to increase as the baby boomer generation nears retirement and unemployment of youth increases. As such, the Korean government needs to improve the policy in keeping with the times.

  8. Sustainability Policy and Environmental Policy

    OpenAIRE

    John C. V. Pezzey

    2001-01-01

    A theoretical, representative agent economy with a depletable resource stock, polluting emissions and productive capital is used to contrast environmental policy, which internalises externalised environmental values, with sustainability policy, which achieves some form of intergenerational equity. The obvious environmental policy comprises an emissions tax and a resource stock subsidy, each equal to the respective external cost or benefit. Sustainability policy comprises an incentive affectin...

  9. Correlated Default and Financial Intermediation

    OpenAIRE

    Gregory Phelan

    2015-01-01

    Financial intermediation naturally arises when knowledge about the aggregate state is valuable for managing investments and lenders cannot easily observe the aggregate state. I show this using a costly enforcement model in which lenders need ex-post incentives to enforce payments from defaulted loans and borrowers' payoffs are correlated. When projects have correlated outcomes, learning the state of one project (via enforcement) provides information about the states of other projects. A large...

  10. Lifetime enhancement for multiphoton absorption in intermediate band solar cells

    International Nuclear Information System (INIS)

    Bezerra, Anibal T; Studart, Nelson

    2017-01-01

    A semiconductor structure consisting of two coupled quantum wells embedded into the intrinsic region of a p – i–n junction is proposed as an intermediate band solar cell with a photon ratchet state, which would lead to increasing the cell efficiency. The conduction subband of the right-hand side quantum well works as the intermediated band, whereas the excited conduction subband of the left-hand side quantum well operates as the ratchet state. The photoelectrons in the intermediate band are scattered through the thin wells barrier and accumulated into the ratchet subband. A rate equation model for describing the charge transport properties is presented. The efficiency of the current generation is analyzed by studying the occupation of the wells subbands, taking into account the charge dynamic behavior provided by the electrical contacts connected to the cell. The current generation efficiency depends essentially from the relations between the generation, recombination rates and the scattering rate to the ratchet state. The inclusion of the ratchet states led to both an increase and a decrease in the cell current depending on the transition rates. This suggests that the coupling between the intermediate band and the ratchet state is a key point in developing an efficient solar cell. (paper)

  11. Lifetime enhancement for multiphoton absorption in intermediate band solar cells

    Science.gov (United States)

    Bezerra, Anibal T.; Studart, Nelson

    2017-08-01

    A semiconductor structure consisting of two coupled quantum wells embedded into the intrinsic region of a p-i-n junction is proposed as an intermediate band solar cell with a photon ratchet state, which would lead to increasing the cell efficiency. The conduction subband of the right-hand side quantum well works as the intermediated band, whereas the excited conduction subband of the left-hand side quantum well operates as the ratchet state. The photoelectrons in the intermediate band are scattered through the thin wells barrier and accumulated into the ratchet subband. A rate equation model for describing the charge transport properties is presented. The efficiency of the current generation is analyzed by studying the occupation of the wells subbands, taking into account the charge dynamic behavior provided by the electrical contacts connected to the cell. The current generation efficiency depends essentially from the relations between the generation, recombination rates and the scattering rate to the ratchet state. The inclusion of the ratchet states led to both an increase and a decrease in the cell current depending on the transition rates. This suggests that the coupling between the intermediate band and the ratchet state is a key point in developing an efficient solar cell.

  12. Management applicability of the intermediate disturbance hypothesis across Mongolian rangeland ecosystems.

    Science.gov (United States)

    Sasaki, Takehiro; Okubo, Satoru; Okayasu, Tomoo; Jamsran, Undarmaa; Ohkuro, Toshiya; Takeuchi, Kazuhiko

    2009-03-01

    The current growing body of evidence for diversity-disturbance relationships suggests that the peaked pattern predicted by the intermediate disturbance hypothesis (IDH) may not be the rule. Even if ecologists could quantify the diversity-disturbance relationship consistent with the IDH, the applicability of the IDH to land management has rarely been addressed. We examined two hypotheses related to the generality and management applicability of the IDH to Mongolian rangeland ecosystems: that the diversity-disturbance relationship varies as a function of landscape condition and that some intermediate scales of grazing can play an important role in terms of sustainable rangeland management through a grazing gradient approach. We quantified the landscape condition of each ecological site using an ordination technique and determined two types of landscape conditions: relatively benign and harsh environmental conditions. At the ecological sites characterized by relatively benign environmental conditions, diversity-disturbance relationships were generally consistent with the IDH, and maximum diversity was observed at some intermediate distance from the source of the grazing gradient. In contrast, the IDH was not supported at most (but not all) sites characterized by relatively harsh environmental conditions. The intermediate levels of grazing were generally located below the ecological threshold representing the points or zones at which disturbance should be limited to prevent drastic changes in ecological conditions, suggesting that there is little "conundrum" with regard to intermediate disturbance in the studied systems in terms of land management. We suggest that the landscape condition is one of the primary factors that cause inconsistencies in diversity-disturbance relationships. The ecological threshold can extend its utility in rangeland management because it also has the compatibility with the maintenance of species diversity. This study thus suggests that some

  13. Transarterial chemoembolization versus resection for intermediate-stage (BCLC B hepatocellular carcinoma

    Directory of Open Access Journals (Sweden)

    Jun Young Kim

    2016-06-01

    Full Text Available Background/Aims: Several studies have suggested that surgical resection (SR can provide a survival benefit over transarterial chemoembolization (TACE for hepatocellular carcinoma (HCC at the intermediate stage according to the Barcelona Clinic Liver Cancer (BCLC staging system. However, the criteria for SR remain to be determined. This study compared the long-term outcome of intermediate-stage HCC patients treated by either TACE or SR as a primary treatment modality, with the aim of identifying the patient subgroup that gained a survival benefit by either modality. Methods: In total, 277 BCLC intermediate-stage HCC patients treated by either TACE (N=225 or SR (N=52 were analyzed. Results: The overall median survival time was significantly better for SR than TACE (61 vs. 30 months, P=0.002. Decision-tree analysis divided patients into seven nodes based on tumor size and number, serum alpha-fetoprotein (AFP level, and Child-Pugh score, and these were then simplified into four subgroups (B1–B4 based on similarities in the overall hazard rate. SR provided a significant survival benefit in subgroup B2, characterized by ‘oligo’ (2–4 nodules of intermediate size (5–10 cm when the AFP levels was <400 ng/ml, or ‘oligo’ (2–4 nodules of small to intermediate size (<10 cm plus a Child-Pugh score of 5 when the AFP level was ≥400 ng/mL (median survival 73 vs. 28 months for SR vs. TACE respectively; P=0.014. The survival rate did not differ significantly between SR and TACE in the other subgroups (B1 and B3. Conclusion: SR provided a survival benefit over TACE in intermediate-stage HCC, especially for patients meeting certain criteria. Re-establishing the criteria for optimal treatment modalities in this stage of HCC is needed to improve survival rates.

  14. 48 CFR 210.001 - Policy.

    Science.gov (United States)

    2010-10-01

    ... DEFENSE ACQUISITION PLANNING MARKET RESEARCH 210.001 Policy. (a) In addition to the requirements of FAR 10.001(a), agencies shall— (i) Conduct market research appropriate to the circumstances before— (A... 109-163); and (ii) Use the results of market research to determine— (A) Whether consolidation of...

  15. Clashing strategic cultures and climate policy

    Energy Technology Data Exchange (ETDEWEB)

    Ceronsky, M.; Hepburn, C.; Obersteiner, M.; Yamagata, Y.

    2004-07-01

    Kagan (2002) argues that the different responses of Europeans and Americans to major strategic and international challenges is not simply due to differences in the current administrations, but rather results from (i) a power gap and (ii) differing ideologies. This article applies Kagan's theory to climate policy, employing terrorism policy as a point of comparison. We argue that the power gap between Europe and America is unable to explain the differences in climate policy. In contrast, the ideology gap may indeed have some explanatory value. Furthermore, we argue that one additional feature is critical - the costs and benefits imposed by climate change and terrorism prevention, and the process by which such costs and benefits are evaluated, differ between America and Europe. (author)

  16. Memory Monitoring and Control in Young and Intermediate-Age Adults

    Directory of Open Access Journals (Sweden)

    Maxciel Zortea

    2015-08-01

    Full Text Available The way adults perceive and regulate learning (metamemory is an important indicator of how they perform on memory tasks. This study assessed memory monitoring, control and performance in young and intermediate-age adults according to item type (with or without semantic relation, type of judgment of learning (JOL - immediate or delayed, and age. Twenty-six young adults (M = 22 years old and 18 intermediate-age adults (M = 47 years old participated, who responded to an experimental paradigm to evaluate metamemory. Results showed that related word-pairs received higher magnitude for the JOLs and better cued-recall scores. JOLs’ accuracy was similar between the age groups, delayed JOLs being more accurate only for young adults. Intermediate-age adults apparently based their allocation of study time less on JOLs or cued-recall than young adults.

  17. Agricultural policy, food policy, and communicable disease policy.

    Science.gov (United States)

    Grant, Wyn

    2012-12-01

    Food and agricultural policy is an essential element of a communicable disease policy. The European Union has developed a more systematic and broadly based interest in questions of food safety and animal health and welfare linked to modernization of the Common Agricultural Policy, reflected in a new treaty obligation on animal welfare. Following the bovine spongiform encephalopathy crisis, moves were made to create a European competency, but implementation and enforcement resources reside with the member states. The European Animal Health Strategy is meant to lead to an EU animal health law, but this has already been constrained by fiscal austerity. The development of such a law may lead to a lowest common denominator formula that does little to enhance consumer protection or improve animal welfare. This is an inherent risk with top-down forms of Europeanization; more attention should be paid to lessons to be learned from bottom-up initiatives of the type used to counteract the bovine diarrhea virus. There will always be a tension among what is good policy for reducing the incidence of communicable disease, policy that is popular with EU citizens, and policy that is acceptable to member states.

  18. Ceftaroline-Resistant, Daptomycin-Tolerant, and Heterogeneous Vancomycin-Intermediate Methicillin-Resistant Staphylococcus aureus Causing Infective Endocarditis.

    Science.gov (United States)

    Nigo, Masayuki; Diaz, Lorena; Carvajal, Lina P; Tran, Truc T; Rios, Rafael; Panesso, Diana; Garavito, Juan D; Miller, William R; Wanger, Audrey; Weinstock, George; Munita, Jose M; Arias, Cesar A; Chambers, Henry F

    2017-03-01

    We report a case of infective endocarditis (IE) caused by ceftaroline-resistant, daptomycin-tolerant, and heterogeneous vancomycin-intermediate methicillin-resistant S. aureus (MRSA). Resistance to ceftaroline emerged in the absence of drug exposure, and the E447K substitution in the active site of PBP2a previously associated with ceftaroline resistance was identified. Additionally, we present evidence of patient-to-patient transmission of the strain within the same unit. This case illustrates the difficulties in treating MRSA IE in the setting of a multidrug-resistant phenotype. Copyright © 2017 American Society for Microbiology.

  19. Reaction intermediates in the catalytic Gif-type oxidation from nuclear inelastic scattering

    Energy Technology Data Exchange (ETDEWEB)

    Rajagopalan, S., E-mail: rajagopalan78@hotmail.com [Indira Gandhi Centre for Atomic Research, Materials Science Group (India); Asthalter, T., E-mail: t.asthalter@web.de [Universität Stuttgart, Institute of Physical Chemistry (Germany); Rabe, V.; Laschat, S. [Universität Stuttgart, Institute of Organic Chemistry (Germany)

    2016-12-15

    Nuclear inelastic scattering (NIS) of synchrotron radiation, also known as nuclear resonant vibrational spectroscopy (NRVS), has been shown to provide valuable insights into metal-centered vibrations at Mössbauer-active nuclei. We present a study of the iron-centered vibrational density of states (VDOS) during the first step of the Gif-type oxidation of cyclohexene with a novel trinuclear Fe{sub 3}(μ{sub 3}-O) complex as catalyst precursor. The experiments were carried out on shock-frozen solutions for different combinations of reactants: Fe{sub 3}(μ{sub 3}-O) in pyridine solution, Fe{sub 3}(μ{sub 3}-O) plus Zn/acetic acid in pyridine without and with addition of either oxygen or cyclohexene, and Fe{sub 3}(μ{sub 3}-O)/Zn/acetic acid/pyridine/cyclohexene (reaction mixture) for reaction times of 1 min, 5 min, and 30 min. The projected VDOS of the Fe atoms was calculated on the basis of pseudopotential density functional calculations. Two possible reaction intermediates were identified as [Fe{sup (III)}(C{sub 5}H{sub 5}N){sub 2}(O{sub 2}CCH{sub 3}){sub 2}]{sup +} and Fe{sup (II)}(C{sub 5}H{sub 5}N){sub 4}(O{sub 2}CCH{sub 3}){sub 2}, yielding evidence that NIS (NRVS) allows to identify the presence of iron-centered intermediates also in complex reaction mixtures.

  20. On contribution of horizontal and intra-layer convection to the formation of the Baltic Sea cold intermediate layer

    Directory of Open Access Journals (Sweden)

    I. Chubarenko

    2010-02-01

    Full Text Available Seasonal cascades down the coastal slopes and intra-layer convection are considered as the two additional mechanisms contributing to the Baltic Sea cold intermediate layer (CIL formation along with conventional seasonal vertical mixing. Field measurements are presented, reporting for the first time the possibility of denser water formation and cascading from the Baltic Sea underwater slopes, which take place under fall and winter cooling conditions and deliver waters into intermediate layer of salinity stratified deep-sea area. The presence in spring within the CIL of water with temperature below that of maximum density (Tmd and that at the local surface in winter time allows tracing its formation: it is argued that the source of the coldest waters of the Baltic CIL is early spring (March–April cascading, arising due to heating of water before reaching the Tmd. Fast increase of the open water heat content during further spring heating indicates that horizontal exchange rather than direct solar heating is responsible for that. When the surface is covered with water, heated above the Tmd, the conditions within the CIL become favorable for intralayer convection due to the presence of waters of Tmd in intermediate layer, which can explain its well-known features – the observed increase of its salinity and deepening with time.

  1. File list: InP.PSC.20.AllAg.iPSC_intermediates [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.PSC.20.AllAg.iPSC_intermediates mm9 Input control Pluripotent stem cell iPSC intermediates...178446,SRX1178444,SRX1178449,SRX1184108,SRX897944,SRX1178447 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/InP.PSC.20.AllAg.iPSC_intermediates.bed ...

  2. File list: InP.PSC.50.AllAg.iPSC_intermediates [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.PSC.50.AllAg.iPSC_intermediates mm9 Input control Pluripotent stem cell iPSC intermediates...178448,SRX1178449,SRX1184108,SRX1178444,SRX897944,SRX1178447 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/InP.PSC.50.AllAg.iPSC_intermediates.bed ...

  3. File list: InP.PSC.05.AllAg.iPSC_intermediates [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.PSC.05.AllAg.iPSC_intermediates mm9 Input control Pluripotent stem cell iPSC intermediates...178445,SRX1178449,SRX1178446,SRX1184108,SRX897944,SRX1178447 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/InP.PSC.05.AllAg.iPSC_intermediates.bed ...

  4. File list: InP.PSC.10.AllAg.iPSC_intermediates [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.PSC.10.AllAg.iPSC_intermediates mm9 Input control Pluripotent stem cell iPSC intermediates...184108,SRX1178445,SRX1178446,SRX1178449,SRX1178447,SRX897944 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/InP.PSC.10.AllAg.iPSC_intermediates.bed ...

  5. Neuroscience Intermediate-Level Care Units Staffed by Intensivists: Clinical Outcomes and Cost Analysis.

    Science.gov (United States)

    Kyeremanteng, Kwadwo; Hendin, Ariel; Bhardwaj, Kalpana; Thavorn, Kednapa; Neilipovitz, Dave; Kubelik, Dalibour; D'Egidio, Gianni; Stotts, Grant; Rosenberg, Erin

    2017-01-01

    With an aging population and increasing numbers of intensive care unit admissions, novel ways of providing quality care at reduced cost are required. Closed neurointensive care units improve outcomes for patients with critical neurological conditions, including decreased mortality and length of stay (LOS). Small studies have demonstrated the safety of intermediate-level units for selected patient populations. However, few studies analyze both cost and safety outcomes of these units. This retrospective study assessed clinical and cost-related outcomes in an intermediate-level neurosciences acute care unit (NACU) before and after the addition of an intensivist to the unit's care team. Starting in October 2011, an intensivist-led model was adopted in a 16-bed NACU unit, including daytime coverage by a dedicated intensivist. Data were obtained from all patients admitted 1 year prior to and 2 years after this intervention. Primary outcomes were LOS and hospital costs. Safety outcomes included mortality and readmissions. Descriptive and analytic statistics were calculated. Individual and total patient costs were calculated based on per-day NACU and ward cost estimates and significance measured using bootstrapping. A total of 2931 patients were included over the study period. Patients were on average 59.5 years and 53% male. The most common reasons for admission were central nervous system (CNS) tumor (27.6%), ischemic stroke (27%), and subarachnoid hemorrhage (11%). Following the introduction of an intensivist, there was a significant reduction in NACU and hospital LOS, by 1 day and 3 days, respectively. There were no differences in readmissions or mortality. Adding an intensivist produced an individual cost savings of US$963 in NACU and US$2687 per patient total hospital stay. An intensivist-led model of intermediate-level neurointensive care staffed by intensivists is safe, decreases LOS, and produces cost savings in a system increasingly strained to provide quality

  6. Gluten-free dough-making of specialty breads: Significance of blended starches, flours and additives on dough behaviour.

    Science.gov (United States)

    Collar, Concha; Conte, Paola; Fadda, Costantino; Piga, Antonio

    2015-10-01

    The capability of different gluten-free (GF) basic formulations made of flour (rice, amaranth and chickpea) and starch (corn and cassava) blends, to make machinable and viscoelastic GF-doughs in absence/presence of single hydrocolloids (guar gum, locust bean and psyllium fibre), proteins (milk and egg white) and surfactants (neutral, anionic and vegetable oil) have been investigated. Macroscopic (high deformation) and macromolecular (small deformation) mechanical, viscometric (gelatinization, pasting, gelling) and thermal (gelatinization, melting, retrogradation) approaches were performed on the different matrices in order to (a) identify similarities and differences in GF-doughs in terms of a small number of rheological and thermal analytical parameters according to the formulations and (b) to assess single and interactive effects of basic ingredients and additives on GF-dough performance to achieve GF-flat breads. Larger values for the static and dynamic mechanical characteristics and higher viscometric profiles during both cooking and cooling corresponded to doughs formulated with guar gum and Psyllium fibre added to rice flour/starch and rice flour/corn starch/chickpea flour, while surfactant- and protein-formulated GF-doughs added to rice flour/starch/amaranth flour based GF-doughs exhibited intermediate and lower values for the mechanical parameters and poorer viscometric profiles. In addition, additive-free formulations exhibited higher values for the temperature of both gelatinization and retrogradation and lower enthalpies for the thermal transitions. Single addition of 10% of either chickpea flour or amaranth flour to rice flour/starch blends provided a large GF-dough hardening effect in presence of corn starch and an intermediate effect in presence of cassava starch (chickpea), and an intermediate reinforcement of GF-dough regardless the source of starch (amaranth). At macromolecular level, both chickpea and amaranth flours, singly added, determined

  7. Improved enzymatic production of phenolated glycerides through alkyl phenolate intermediate

    DEFF Research Database (Denmark)

    Yang, Zhiyong; Feddern, Vivian; Glasius, Marianne

    2011-01-01

    This work reported a novel approach for synthesis of dihydrocaffoylated glycerides, consisting of 2 steps: enzymatic synthesis of octyl dihydrocaffeate (as a synthetic intermediate) from octanol and dihydrocaffeic acid (DHCA), and enzymatic interesterification of triglycerides with octyl dihydroc......This work reported a novel approach for synthesis of dihydrocaffoylated glycerides, consisting of 2 steps: enzymatic synthesis of octyl dihydrocaffeate (as a synthetic intermediate) from octanol and dihydrocaffeic acid (DHCA), and enzymatic interesterification of triglycerides with octyl...

  8. Electron microscopic analysis of rotavirus assembly-replication intermediates

    International Nuclear Information System (INIS)

    Boudreaux, Crystal E.; Kelly, Deborah F.; McDonald, Sarah M.

    2015-01-01

    Rotaviruses (RVs) replicate their segmented, double-stranded RNA genomes in tandem with early virion assembly. In this study, we sought to gain insight into the ultrastructure of RV assembly-replication intermediates (RIs) using transmission electron microscopy (EM). Specifically, we examined a replicase-competent, subcellular fraction that contains all known RV RIs. Three never-before-seen complexes were visualized in this fraction. Using in vitro reconstitution, we showed that ~15-nm doughnut-shaped proteins in strings were nonstructural protein 2 (NSP2) bound to viral RNA transcripts. Moreover, using immunoaffinity-capture EM, we revealed that ~20-nm pebble-shaped complexes contain the viral RNA polymerase (VP1) and RNA capping enzyme (VP3). Finally, using a gel purification method, we demonstrated that ~30–70-nm electron-dense, particle-shaped complexes represent replicase-competent core RIs, containing VP1, VP3, and NSP2 as well as capsid proteins VP2 and VP6. The results of this study raise new questions about the interactions among viral proteins and RNA during the concerted assembly–replicase process. - Highlights: • Rotaviruses replicate their genomes in tandem with early virion assembly. • Little is known about rotavirus assembly-replication intermediates. • Assembly-replication intermediates were imaged using electron microscopy

  9. Electron microscopic analysis of rotavirus assembly-replication intermediates

    Energy Technology Data Exchange (ETDEWEB)

    Boudreaux, Crystal E.; Kelly, Deborah F. [Virginia Tech Carilion School of Medicine and Research Institute, Roanoke, VA (United States); McDonald, Sarah M., E-mail: mcdonaldsa@vtc.vt.edu [Virginia Tech Carilion School of Medicine and Research Institute, Roanoke, VA (United States); Department of Biomedical Sciences and Pathobiology, Virginia—Maryland Regional College of Veterinary Medicine, Blacksburg, VA (United States)

    2015-03-15

    Rotaviruses (RVs) replicate their segmented, double-stranded RNA genomes in tandem with early virion assembly. In this study, we sought to gain insight into the ultrastructure of RV assembly-replication intermediates (RIs) using transmission electron microscopy (EM). Specifically, we examined a replicase-competent, subcellular fraction that contains all known RV RIs. Three never-before-seen complexes were visualized in this fraction. Using in vitro reconstitution, we showed that ~15-nm doughnut-shaped proteins in strings were nonstructural protein 2 (NSP2) bound to viral RNA transcripts. Moreover, using immunoaffinity-capture EM, we revealed that ~20-nm pebble-shaped complexes contain the viral RNA polymerase (VP1) and RNA capping enzyme (VP3). Finally, using a gel purification method, we demonstrated that ~30–70-nm electron-dense, particle-shaped complexes represent replicase-competent core RIs, containing VP1, VP3, and NSP2 as well as capsid proteins VP2 and VP6. The results of this study raise new questions about the interactions among viral proteins and RNA during the concerted assembly–replicase process. - Highlights: • Rotaviruses replicate their genomes in tandem with early virion assembly. • Little is known about rotavirus assembly-replication intermediates. • Assembly-replication intermediates were imaged using electron microscopy.

  10. Lithium hydride doped intermediate connector for high-efficiency and long-term stable tandem organic light-emitting diodes.

    Science.gov (United States)

    Ding, Lei; Tang, Xun; Xu, Mei-Feng; Shi, Xiao-Bo; Wang, Zhao-Kui; Liao, Liang-Sheng

    2014-10-22

    Lithium hydride (LiH) is employed as a novel n-dopant in the intermediate connector for tandem organic light-emitting diodes (OLEDs) because of its easy coevaporation with other electron transporting materials. The tandem OLEDs with two and three electroluminescent (EL) units connected by a combination of LiH doped 8-hydroxyquinoline aluminum (Alq3) and 1,4,5,8,9,11-hexaazatriphenylene-hexacarbonitrile (HAT-CN) demonstrate approximately 2-fold and 3-fold enhancement in current efficiency, respectively. In addition, no extra voltage drop across the intermediate connector is observed. Particularly, the lifetime (T75%) in the tandem OLED with two and three EL units is substantially improved by 3.8 times and 7.4 times, respectively. The doping effect of LiH into Alq3, the charge injection, and transport characteristics of LiH-doped Alq3 are further investigated by ultraviolet photoelectron spectroscopy (UPS) and X-ray photoemission spectroscopy (XPS).

  11. Smoking Policy Change Within Permanent Supportive Housing.

    Science.gov (United States)

    Petersen, Anne Berit; Stewart, Holly C; Walters, Jon; Vijayaraghavan, Maya

    2018-04-01

    Smoke-free policies effectively reduce secondhand smoke (SHS) exposure among non-smokers, and reduce consumption, encourage quit attempts, and minimize relapse to smoking among smokers. Such policies are uncommon in permanent supportive housing (PSH) for formerly homeless individuals. In this study, we collaborated with a PSH provider in San Diego, California to assess a smoke-free policy that restricted indoor smoking. Between August and November 2015, residents completed a pre-policy questionnaire on attitudes toward smoke-free policies and exposure to secondhand smoke, and then 7-9 months after policy implementation residents were re-surveyed. At follow-up, there was a 59.7% reduction in indoor smoking. The proportion of residents who identified as current smokers reduced by 13% (95% CI: -38, 10.2). The proportion of residents who reported never smelling SHS indoors (apartment 24.2%, 95% CI: 4.2, 44.1; shared areas 17.2%, 95% CI: 1.7, 32.7); in outdoor areas next to the living unit (porches or patio 56.7%, 95% CI: 40.7, 72.8); and in other outdoor areas (parking lot 28.6%, 95% CI: 8.3, 48.9) was lower post-policy compared with pre-policy. Overall, resident support increased by 18.7%; however, the greatest increase in support occurred among current smokers (from 14.8 to 37.5%). Fewer current smokers reported that the policy would enable cessation at post-policy compared to pre-policy. Our findings demonstrate the feasibility of implementing smoke-free policies in PSH for formerly homeless adults. However, policy alone appears insufficient to trigger change in smoking behavior, highlighting the need for additional cessation resources to facilitate quitting.

  12. Intermediates and the folding of proteins L and G

    Energy Technology Data Exchange (ETDEWEB)

    Brown, Scott; Head-Gordon, Teresa

    2003-07-01

    We use a minimalist protein model, in combination with a sequence design strategy, to determine differences in primary structure for proteins L and G that are responsible for the two proteins folding through distinctly different folding mechanisms. We find that the folding of proteins L and G are consistent with a nucleation-condensation mechanism, each of which is described as helix-assisted {beta}-1 and {beta}-2 hairpin formation, respectively. We determine that the model for protein G exhibits an early intermediate that precedes the rate-limiting barrier of folding and which draws together misaligned secondary structure elements that are stabilized by hydrophobic core contacts involving the third {beta}-strand, and presages the later transition state in which the correct strand alignment of these same secondary structure elements is restored. Finally the validity of the targeted intermediate ensemble for protein G was analyzed by fitting the kinetic data to a two-step first order reversible reaction, proving that protein G folding involves an on-pathway early intermediate, and should be populated and therefore observable by experiment.

  13. Bridge: Intelligent Tutoring with Intermediate Representations

    Science.gov (United States)

    1988-05-01

    Research and Development Center and Psychology Department University of Pittsburgh Pittsburgh, PA. 15260 The Artificial Intelligence and Psychology...problem never introduces more than one unfamiliar plan. Inteligent Tutoring With Intermediate Representations - Bonar and Cunniigbam 4 You must have a... Inteligent Tutoring With ntermediate Representations - Bonar and Cunningham 7 The requirements are specified at four differcnt levels, corresponding to

  14. Sexually Transmitted Disease Prevention Policies in the United States: Evidence and Opportunities.

    Science.gov (United States)

    Leichliter, Jami S; Seiler, Naomi; Wohlfeiler, Dan

    2016-02-01

    Policies are an important part of public health interventions, including in the area of sexually transmitted disease (STD) prevention. Similar to other tools used in public health, policies are often evaluated to determine their usefulness. Therefore, we conducted a nonsystematic review of policy evidence for STD prevention. Our review considers assessments or evaluations of STD prevention-specific policies, health care system policies, and other, broader policies that have the potential to impact STD prevention through social determinants of health. We also describe potential policy opportunity in these areas. It should be noted that we found gaps in policy evidence for some areas; thus, additional research would be useful for public health policy interventions for STD prevention.

  15. An Exploration of Linguistic Neo-Colonialism through Educational Language Policy--An Irish Perspective

    Science.gov (United States)

    Dillon, Anna

    2016-01-01

    In this paper, educational language policy is explored through the lens of linguistic neo-colonialism in Ireland in the case of learners of English as an Additional Language. The perspective of Ireland as a decolonized nation may have an impact on current language policy. Arguments for an additive approach to language and identity, language…

  16. Hoxd11 specifies a program of metanephric kidney development within the intermediate mesoderm of the mouse embryo.

    Science.gov (United States)

    Mugford, Joshua W; Sipilä, Petra; Kobayashi, Akio; Behringer, Richard R; McMahon, Andrew P

    2008-07-15

    The mammalian kidney consists of an array of tubules connected to a ductal system that collectively function to control water/salt balance and to remove waste from the organisms' circulatory system. During mammalian embryogenesis, three kidney structures form within the intermediate mesoderm. The two most anterior structures, the pronephros and the mesonephros, are transitory and largely non-functional, while the most posterior, the metanephros, persists as the adult kidney. We have explored the mechanisms underlying regional specific differentiation of the kidney forming mesoderm. Previous studies have shown a requirement for Hox11 paralogs (Hoxa11, Hoxc11 and Hoxd11) in metanephric development. Mice lacking all Hox11 activity fail to form metanephric kidney structures. We demonstrate that the Hox11 paralog expression is restricted in the intermediate mesoderm to the posterior, metanephric level. When Hoxd11 is ectopically activated in the anterior mesonephros, we observe a partial transformation to a metanephric program of development. Anterior Hoxd11(+) cells activate Six2, a transcription factor required for the maintenance of metanephric tubule progenitors. Additionally, Hoxd11(+) mesonephric tubules exhibit an altered morphology and activate several metanephric specific markers normally confined to distal portions of the functional nephron. Collectively, our data support a model where Hox11 paralogs specify a metanephric developmental program in responsive intermediate mesoderm. This program maintains tubule forming progenitors and instructs a metanephric specific pattern of nephron differentiation.

  17. Two different strategies of host manipulation allow parasites to persist in intermediate-definitive host systems

    NARCIS (Netherlands)

    Vries, de L.J.; Langevelde, van F.

    2018-01-01

    Trophically transmitted parasites start their development in an intermediate host, before they finish the development in their definitive host when the definitive host preys on the intermediate host. In intermediate-definitive host systems, two strategies of host manipulation have been evolved:

  18. Macro-economic effects of additional energy conservation in the European Community

    International Nuclear Information System (INIS)

    Sips, H.W.; Bakker, L.; Muizelaar, J.; Velthuijsen, J.W.

    1991-01-01

    The aim of the title study is to evaluate the environmental and economic consequences of additional energy conservation in five Western European countries: the Netherlands, the Federal Republic of Germany, the United Kingdom, France and Italy. In the first part of the study the economic effects of a policy, in which additional energy conservation is realized only for the Netherlands, is calculated. In this report the results are presented. The calculated results of the economic effects of a coordinated energy conservation policy in the abovementioned countries will be published in a separate report. The effects of three policy variants will be evaluated: the non-financial policy variant, the shift of the financial burden variant, and the variant in which the levies are not compensated.The starting point for the first variant is an autonomous realization of the energy conservation. The basis of the second variant is that an equal amount of energy can be saved by means of a substantial energy levy. The profits of this levy can be used to reduce the financial burden of labour. For the economic calculations use has been made of the HERMES-model. Every member of the European Community has developed such a macro-economic model. In chapter two the different starting points for the calculations are outlined, with special attention to descriptions of the policy variants, the model-input and the basic projection. In chapter three the economic effects of the policy variants are presented and discussed. In chapter four the energy conservation and the environmental effects of the variants are dealt with. The most important conclusion of this study is that a considerable amount of energy can be saved, which will have positive effects on the economy and the environment. 8 figs., 20 tabs., 6 apps., 32 refs

  19. Radiotherapy and hormone therapy in intermediate risk prostate cancer: a critical review

    International Nuclear Information System (INIS)

    Franco, Rejane Carolina; Souhami, Luis

    2015-01-01

    Introduction: The standard treatment for patients with high risk prostate cancer is the combined use of radiation therapy (RT ) and hormone therapy (HT). In regards to patients stratified as intermediate risk, the use of HT associated with RT remains controversial, and its use should be carefully planned and based on available evidence. Objective: To critically assess results of randomized studies published in the literature that associated the use of HT of short duration with an average period of 6 months with RT in the treatment of patients with localized prostate cancer classified as intermediate risk. Method: Only randomized studies comparing these treatments were eligible for this review. A structured search through 'PubMed' was carried out using the terms 'androgen suppression therapy', 'radiotherapy', 'randomized trials', 'phase 3 trials', 'prostate cancer' and 'intermediate risk'. Results: Four randomized studies comparing RT alone to RT plus short course HT were found and selected. The majority of the trials had a mixed population of intermediate and high risk disease and did not include patients with only intermediate risk. Despite that, there appears to be a significant benefit for the combined approach regarding disease-free survival, biochemical free survival and overall survival. Conclusion: The randomized studies published so far suggest improved outcomes for the group of patients receiving RT and short course HT. Data from randomized trials comparing RT alone to RT and short course HT in patients with intermediate risk only are forthcoming. (author)

  20. On spallation and fragmentation of heavy ions at intermediate energies

    International Nuclear Information System (INIS)

    Musulmanbekov, G.; Al-Haidary, A.

    2002-01-01

    A new code for simulation of spallation and (multi)fragmentation of nuclei in proton and nucleus induced collisions at intermediate and high energies is developed. The code is a combination of modified intranuclear cascade model with traditional fission - evaporation part and multifragmentation part based on lattice representation of nuclear structure and percolation approach. The production of s-wave resonances and formation time concept included into standard intranuclear cascade code provides correct calculation of excitation energy of residues. This modified cascade code served as a bridge between low and high energy model descriptions of nucleus-nucleus collisions. A good agreement with experiments has been obtained for multiparticle production at intermediate and relatively high energies. Nuclear structure of colliding nuclei is represented as face centered cubic lattice. This representation, being isomorphic to the shell model of nuclear structure, allows to apply percolation approach for nuclear fragmentation. The offered percolation model includes both site and bond percolation. Broken sites represent holes left by nucleons knocked out at cascade state. Therefore, in the first cascade stage mutual rescattering of the colliding nuclei results in knocking some nucleons out of them. After this fast stage paltrily destruct and excited residues remain. On the second stage residual nuclei either evaporate nucleons and light nuclei up to alpha-particles or fragment into pieces with intermediate masses. The choice depends on residue's destruction degree. At low excitation energy and small destruction of the residue the evaporation and fission mechanisms are preferable. The more excitation energy and destruction the more probability of (multi)fragmentation process. Moreover, the more destruction degree of the residual the more the site percolation probability. It is concluded, that at low and intermediate excitation energies the fragmentation of nuclei is slow