WorldWideScience

Sample records for intermediary gains emission

  1. Emission and gain studies of the Tl-Hg excimer

    Energy Technology Data Exchange (ETDEWEB)

    Chilukuri, S.; Nayfeh, M.H.

    1978-11-01

    The pressure and temperature dependence of the Tl-Hg excimer emission in the visible from an rf excited discharge has been studied. The gain of the system in the blue band at 4585 A is probed with an Ar-ion laser. With gain sensitivity limited to 1/2% due to beam steering and defocusing effects, the system has no gain.

  2. Optical gain and stimulated emission in periodic nanopatterned crystalline silicon.

    Science.gov (United States)

    Cloutier, Sylvain G; Kossyrev, Pavel A; Xu, Jimmy

    2005-12-01

    Persistent efforts have been made to achieve efficient light emission from silicon in the hope of extending the reach of silicon technology into fully integrated optoelectronic circuits, meeting the needs for high-bandwidth intrachip and interchip connects. Enhanced light emission from silicon is known to be theoretically possible, enabled mostly through quantum-confinement effects. Furthermore, Raman-laser conversion was demonstrated in silicon waveguides. Here we report on optical gain and stimulated emission in uniaxially nanopatterned silicon-on-insulator using a nanopore array as an etching mask. In edge-emission measurements, we observed threshold behaviour, optical gain, longitudinal cavity modes and linewidth narrowing, along with a collimated far-field pattern, all indicative of amplification and stimulated emission. The sub-bandgap 1,278 nm emission peak is attributed to A-centre mediated phononless direct recombination between trapped electrons and free holes. The controlled nanoscale silicon engineering, combined with the low material loss in this sub-bandgap spectral range and the long electron lifetime in such A-type trapping centres, gives rise to the measured optical gain and stimulated emission and provides a new pathway to enhance light emission from silicon.

  3. Hybrid intermediaries

    OpenAIRE

    Cetorelli, Nicola

    2014-01-01

    I introduce the concept of hybrid intermediaries: financial conglomerates that control a multiplicity of entity types active in the "assembly line" process of modern financial intermediation, a system that has become known as shadow banking. The complex bank holding companies of today are the best example of hybrid intermediaries, but I argue that financial firms from the "nonbank" space can just as easily evolve into conglomerates with similar organizational structure, thus acquiring the cap...

  4. Gain optimization method of a DQW superluminescent diode with broad multi-state emission

    KAUST Repository

    Dimas, Clara E.

    2010-01-01

    Optimizing gain through systematic methods of varying current injection schemes analytically is significant to maximize experimentally device yield and evaluation. Various techniques are used to calculate the amplified spontaneous emission (ASE) gain for light emitting devices consisting of single-section and multiple-sections of even length. Recently double quantum well (DQW) superluminescent diodes (SLD) have shown a broad multi-state emission due to mutlielectrodes of non-equal lengths and at high non-equal current densities. In this study, we adopt an improved method utilizing an ASE intensity ratio to calibrate a gain curve based on the sum of the measured ASE spectra to efficiently estimate the gain. Although the laser gain for GaAs/AlGaAs material is well studied, the ASE gain of SLD devices has not been systematically studied particular to further explain the multiple-state emission observed in fabricated devices. In addition a unique gain estimate was achieved where the excited state gain clamps prior to the ground state due to approaching saturation levels. In our results, high current densities in long sectioned active regions achieved sufficient un-truncated gain that show evidence of excited state emission has been observed.

  5. Amplified spontaneous emission spectrum and gain characteristic of a two-electrode semiconductor optical amplifier*

    Institute of Scientific and Technical Information of China (English)

    Wang Hanchao; Huang Lirong; Shi Zhongwei

    2011-01-01

    A two-electrode multi-quantum-well semiconductor optical amplifier is designed and fabricated. The amplified spontaneous emission (ASE) spectrum and gain were measured and analyzed. It is shown that the ASE spectrum and gain characteristic are greatly influenced by the distribution of the injection current density. By changing the injection current density of two electrodes, the full width at half maximum, peak wavelength, peak power of the ASE spectrum and the gain characteristic can be easily controlled.

  6. Development of the GAINS-KOREA Base Year Emission Inventory for Criteria Air Pollutants: Issues in Linking the Korea NEI to the GAINS Framework

    Science.gov (United States)

    Lee, Y. M.; Woo, J. H.; Kim, H. K.; Choi, K. C.; Kim, Y.; Ahn, Y. H.; Lee, J. B.; Song, C. K.; Han, J. S.

    2014-12-01

    In the era of air pollution and climate change, we should have reliable outlooks of national air pollutant and GHGs emission, which are also important components of international environmental policy negotiation. The Greenhouse gas - Air pollution Interactions and Synergies (GAINS) model has been developed as a tool to identify reasonable emission forecast and mitigation strategies that achieve air quality and greenhouse gas related targets simultaneously at least cost. Recently, Konkuk University and IIASA has been jointly developing the GAINS-Korea Model by reflecting domestic emission activities and environmental conditions. One of the most important challenges for developing GAINS-Korea model is to reproduce CAPSS - the national emissions inventory of Korea- in the GAINS framework. Matching two different databases are not easy because of different sector classification schemes, estimation methods, and etc. In this study, we developed a base year emissions of the GAINS-Korea for the criteria air pollutants using CAPSS. A new set of methodologies to link national inventory to international framework (GAINS) were introduced so that the GAINS-Korea can produce realistic emission outlooks and test control alternatives. We will discuss several underlying issues, such as improvement of accuracy for mapping, conversion, for our base year emission inventory development in site.

  7. Temperature dependent direct-bandgap light emission and optical gain of Ge

    Science.gov (United States)

    Zhi, Liu; Chao, He; Dongliang, Zhang; Chuanbo, Li; Chunlai, Xue; Yuhua, Zuo; Buwen, Cheng

    2016-05-01

    Band structure, electron distribution, direct-bandgap light emission, and optical gain of tensile strained, n-doped Ge at different temperatures were calculated. We found that the heating effects not only increase the electron occupancy rate in the Γ valley of Ge by thermal excitation, but also reduce the energy difference between its Γ valley and L valley. However, the light emission enhancement of Ge induced by the heating effects is weakened with increasing tensile strain and n-doping concentration. This phenomenon could be explained by that Ge is more similar to a direct bandgap material under tensile strain and n-doping. The heating effects also increase the optical gain of tensile strained, n-doped Ge at low temperature, but decrease it at high temperature. At high temperature, the hole and electron distributions become more flat, which prevent obtaining higher optical gain. Meanwhile, the heating effects also increase the free-carrier absorption. Therefore, to obtain a higher net maximum gain, the tensile strained, n-doped Ge films on Si should balance the gain increased by the heating effects and the optical loss induced by the free-carrier absorption. Project supported by the National Basic Research Development Program of China (Grant No. 2013CB632103) and the National Natural Science Foundation of China (Grant Nos. 61377045, 61435013, and 61176013).

  8. 42 CFR 421.100 - Intermediary functions.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Intermediary functions. 421.100 Section 421.100... (CONTINUED) MEDICARE PROGRAM MEDICARE CONTRACTING Intermediaries § 421.100 Intermediary functions. An agreement between CMS and an intermediary specifies the functions to be performed by the intermediary....

  9. Economic innovation and efficiency gains as the driving force for accelerating carbon dioxide emissions

    Science.gov (United States)

    Garrett, T. J.

    2012-12-01

    It is normally assumed that gains in energy efficiency are one of the best routes that society has available to it for stabilizing future carbon dioxide emissions. For a given degree of economic productivity less energy is consumed and a smaller quantity of fossil fuels is required. While certainly this observation is true in the instant, it ignores feedbacks in the economic system such that efficiency gains ultimately lead to greater energy consumption: taken as a global whole, they permit civilization to accelerate its expansion into the energy reserves that sustain it. Here this argument is formalized from a general thermodynamic perspective. The core result is that there exists a fixed, time-independent link between a very general representation of global inflation-adjusted economic wealth (units currency) and civilization's total capacity to consume power (units energy per time). Based on 40 years of available statistics covering more than a tripling of global GDP and a doubling of wealth, this constant has a value of 7.1 +/- 0.01 Watts per one thousand 2005 US dollars. Essentially, wealth is power. Civilization grows by dissipating power in order to sustain all its current activities and to incorporate more raw material into its existing structure. Growth of its structure is related to economic production, so more energy efficient economic production facilitates growth. Growth is into the reserves that sustain civilization, in which case there is a positive feedback in the economic system whereby energy efficiency gains ultimately "backfire" if their intended purpose is to reduce energy consumption and carbon dioxide emissions. The analogy that can be made is to a growing child: a healthy child who efficiently incorporates food into her structure grows quickly and is able to consume more in following years. Economically, an argument is made that, for a range of reasons, there are good reasons to refer to efficiency gains as economic "innovation", both for

  10. Large gain in air quality compared to an alternative anthropogenic emissions scenario

    Science.gov (United States)

    Daskalakis, Nikos; Tsigaridis, Kostas; Myriokefalitakis, Stelios; Fanourgakis, George S.; Kanakidou, Maria

    2016-08-01

    During the last 30 years, significant effort has been made to improve air quality through legislation for emissions reduction. Global three-dimensional chemistry-transport simulations of atmospheric composition over the past 3 decades have been performed to estimate what the air quality levels would have been under a scenario of stagnation of anthropogenic emissions per capita as in 1980, accounting for the population increase (BA1980) or using the standard practice of neglecting it (AE1980), and how they compare to the historical changes in air quality levels. The simulations are based on assimilated meteorology to account for the year-to-year observed climate variability and on different scenarios of anthropogenic emissions of pollutants. The ACCMIP historical emissions dataset is used as the starting point. Our sensitivity simulations provide clear indications that air quality legislation and technology developments have limited the rapid increase of air pollutants. The achieved reductions in concentrations of nitrogen oxides, carbon monoxide, black carbon, and sulfate aerosols are found to be significant when comparing to both BA1980 and AE1980 simulations that neglect any measures applied for the protection of the environment. We also show the potentially large tropospheric air quality benefit from the development of cleaner technology used by the growing global population. These 30-year hindcast sensitivity simulations demonstrate that the actual benefit in air quality due to air pollution legislation and technological advances is higher than the gain calculated by a simple comparison against a constant anthropogenic emissions simulation, as is usually done. Our results also indicate that over China and India the beneficial technological advances for the air quality may have been masked by the explosive increase in local population and the disproportional increase in energy demand partially due to the globalization of the economy.

  11. Large Gain in Air Quality Compared to an Alternative Anthropogenic Emissions Scenario

    Science.gov (United States)

    Daskalakis, Nikos; Tsigaridis, Kostas; Myriokefalitakis, Stelios; Fanourgakis, George S.; Kanakidou, Maria

    2016-01-01

    During the last 30 years, significant effort has been made to improve air quality through legislation for emissions reduction. Global three-dimensional chemistrytransport simulations of atmospheric composition over the past 3 decades have been performed to estimate what the air quality levels would have been under a scenario of stagnation of anthropogenic emissions per capita as in 1980, accounting for the population increase (BA1980) or using the standard practice of neglecting it (AE1980), and how they compare to the historical changes in air quality levels. The simulations are based on assimilated meteorology to account for the yearto- year observed climate variability and on different scenarios of anthropogenic emissions of pollutants. The ACCMIP historical emissions dataset is used as the starting point. Our sensitivity simulations provide clear indications that air quality legislation and technology developments have limited the rapid increase of air pollutants. The achieved reductions in concentrations of nitrogen oxides, carbon monoxide, black carbon, and sulfate aerosols are found to be significant when comparing to both BA1980 and AE1980 simulations that neglect any measures applied for the protection of the environment. We also show the potentially large tropospheric air quality benefit from the development of cleaner technology used by the growing global population. These 30-year hindcast sensitivity simulations demonstrate that the actual benefit in air quality due to air pollution legislation and technological advances is higher than the gain calculated by a simple comparison against a constant anthropogenic emissions simulation, as is usually done. Our results also indicate that over China and India the beneficial technological advances for the air quality may have been masked by the explosive increase in local population and the disproportional increase in energy demand partially due to the globalization of the economy.

  12. Positioning intermediary organisations in innovation

    NARCIS (Netherlands)

    Lente, van H.; Boon, W.P.C.; Klerkx, L.W.A.

    2010-01-01

    Abstract: Intermediary organisations are important in innovation systems and their contributions seem to increase. The central ambition of this paper is to understand and analyse the position of intermediaries within innovation networks. We use so-called positioning theory, where roles are outcomes

  13. Intermediaries in sustainable urban transitions

    DEFF Research Database (Denmark)

    Hoffmann, Birgitte; Agger, Annika

    The paper explores how local public authorities can support and facilitate projects, which promote sustainable transi-tion in urban neighbourhoods, by supporting local intermediaries. The role of intermediaries can be performed by a variety of actors such as public housing associations; NGO......´s, or semi public institutions. Our claim is that interme-diary actors have the potential to reach a broader scope of citizens due to their particular role in between public au-thorities and civil society. The key question of the paper is how the intermediary actors facilitate citizens' participatory...... processes in sustainable urban management and the paper explores the development of communities of practise as a way to develop learning processes and new practises? The aim is to analyse approaches of involving citizens and how they contribute to the development of new actor configurations in urban social...

  14. On the efficiency gains of emissions trading when climate deals are non-cooperative

    Energy Technology Data Exchange (ETDEWEB)

    Godal, Odd; Holtsmark, Bjart

    2011-07-15

    This paper studies, in a numerical environment, climate treaties with emissions trading when national quotas result from strategic individual choice. We find that the larger the number of parties to the deal, the smaller are the emissions reductions and the lower the welfare. If insisting on stability with respect to participation, climate treaties involve few parties and yield practically no emissions reductions. While these results contrast with some optimistic studies, our numerical example conforms established results if modelling the problem in the more traditional sense. (Author)

  15. Intermediaries in sustainable urban transitions

    DEFF Research Database (Denmark)

    Hoffmann, Birgitte; Agger, Annika

    the development of new practises plays a part in multi level transitions. Empirically, the article is based on case studies from Denmark of local environmental centres, green guides etc. that have performed innovative forms of involving citizens in sustainable urban development. The empirical material......The paper explores how local public authorities can support and facilitate projects, which promote sustainable transi-tion in urban neighbourhoods, by supporting local intermediaries. The role of intermediaries can be performed by a variety of actors such as public housing associations; NGO...... processes in sustainable urban management and the paper explores the development of communities of practise as a way to develop learning processes and new practises? The aim is to analyse approaches of involving citizens and how they contribute to the development of new actor configurations in urban social...

  16. NEC-2020 emission reduction scenarios

    DEFF Research Database (Denmark)

    Slentø, Erik; Nielsen, Ole-Kenneth; Hoffmann, Leif

    The upcoming NEC-2020 EU directive sets up emission ceilings for NOX, SO2, NH3, NMVOC and PM in order to meet the environmental exposure targets of the Thematic Strategy. This report contains an assessment of intermediary emission reduction scenarios for Denmark, computed by the GAINS model 2007......, which serves as the basis for the pending negotiations in EU. The assessment is brought up to date by including a brief evaluation of the new reduction scenarios published in 2008, founding the European Commission NEC-2020 directive proposal....

  17. Cybersecurity via Intermediaries: Analyzing Security Measurements to Understand Intermediary Incentives and Inform Public Policy

    NARCIS (Netherlands)

    Asghari, H.

    2016-01-01

    Research in the field of information security economics has clarified how attacker and defender incentives affect cybersecurity. It has also highlighted the role of intermediaries in strengthening cybersecurity. Intermediaries are organizations and firms that provide the Internet’s infrastructure

  18. Energy use, efficiency gains and emission abatement in transitional industrialised economies. Poland and the Baltic states

    Energy Technology Data Exchange (ETDEWEB)

    Salay, Juergen

    1999-05-01

    This thesis is a study of how energy use and air pollution in Poland, Estonia, Latvia and Lithuania have been affected by the economic transition after 1989. It consists of six articles, which examine three different aspects of these changes. The first group of articles analyses the structure of energy use in the Baltic states (Article 1) and Poland (Articles 2 and 3) at the outset of transition. The results show that these countries had a primary energy consumption per GDP which was two to three times higher than in developed market economics because of a more energy intensive structure of the economy and higher specific energy intensities in many sectors of the economy. They also had significantly higher levels of air pollution per primary energy consumption and GDP because of a heavy reliance on fossil fuels, an energy intensive economy and an ineffective control of emissions. The deep fall in energy consumption during the first phase of transition was due to a sharp drop in industrial output and higher fuel prices. In the Baltic states, part of the fall in energy consumption was the result of shortfalls in the supply of oil and gas from Russia. The second group of articles (Articles 4 and 5) examines changes in electricity production, fuel consumption, generation efficiency and sulphur dioxide (SO{sub 2}) emissions in the Polish power industry between 1988 and 1997. The results show that SO{sub 2} emissions dropped by 45 per cent between 1988 and 1997. The drop in emissions was partly the result of a fall in economic activity and electricity production in the early 1990s. Other reasons were more important. One reason was the restructuring of the power industry, during which hard budget constraints were introduced and the price of coal was raised. Another reason for the fall in emissions was the reorganisation and stricter enforcement of environmental protection. Together, these reforms created strong incentives for power plants to switch to high-quality coal

  19. 76 FR 62408 - Ocean Transportation Intermediary License; Reissuance

    Science.gov (United States)

    2011-10-07

    ... COMMISSION Ocean Transportation Intermediary License; Reissuance Notice is hereby given that the following Ocean Transportation Intermediary licenses have been reissued by the Federal Maritime Commission... Commission pertaining to the licensing of Ocean Transportation Intermediaries, 46 CFR part 515. License...

  20. 75 FR 14160 - Ocean Transportation Intermediary License Applicants

    Science.gov (United States)

    2010-03-24

    ...-Operating Common Carrier and Ocean Freight Forwarder--Ocean Transportation Intermediary pursuant to section...-Vessel-Operating Common Carrier and Ocean Freight Forwarder Transportation Intermediary: Reliable... Freight Forwarder--Ocean Transportation Intermediary: Jeffery Raymond Sewell dba Cargo Unlimited Worldwide...

  1. 75 FR 4560 - Ocean Transportation Intermediary License Applicants

    Science.gov (United States)

    2010-01-28

    ...-Operating Common Carrier and Ocean Freight Forwarder--Ocean Transportation Intermediary pursuant to section..., President. Non-Vessel-Operating Common Carrier and Ocean Freight Forwarder Ocean Transportation Intermediary..., President/Secretary (Qualifying Individual). Ocean Freight Forwarder--Ocean Transportation Intermediary...

  2. 76 FR 18007 - Intermediary Lending Pilot Program

    Science.gov (United States)

    2011-04-01

    ... ADMINISTRATION 13 CFR Part 109 RIN 3245-AG18 Intermediary Lending Pilot Program AGENCY: Small Business... Intermediary Lending Pilot (ILP) program. The ILP program is a three- year pilot program in which SBA will make... Lending Pilot (ILP) program. Under the ILP program, SBA will provide loans to selected nonprofit...

  3. How do Innovation Intermediaries add Value?

    DEFF Research Database (Denmark)

    Tran, Yen; Hsuan, Juliana; Mahnke, Volker

    2011-01-01

    Innovation intermediaries are increasingly being used in practice, but there is little concrete theoretical guidance on when and how they add value to client's new product development (NPD) processes. This paper develops propositions on innovation intermediaries value-added based on a detailed case...... types of specific intermediary capabilities (best-cost capabilities, timing-capabilities, market-response capabilities, and product solution capabilities) increases value added in clients' NDP processes....... study of an innovation intermediary's relations to three major clients in the European apparel fashion industry. We identify key contingencies to an innovation intermediary's value added (e.g. NDP speed and complexity of involvement). We also suggest a framework that specifies when a combination of four...

  4. Particle reduction strategies - PAREST. Gridded European emission data for projection years 2010, 2015 and 2020 based on the IIASA GAINS NEC scenarios. Teilbericht

    Energy Technology Data Exchange (ETDEWEB)

    Gon, Hugo Denier van der; Visschedijk, Antoon; Brugh, Hans van den [TNO Earth, Environment and Life Sciences, Utrecht (Netherlands)

    2013-06-15

    Projected emissions for selected scenarios for the years 2010, 2015 and 2020 were obtained from the GAINS NEC scenario reports and distributed on a high resolution over Europe using the TNO gridding tools. These emission maps are available as model input in the PAREST project to model the contribution of Europe to air quality in Germany in 2010, 2015 and 2020 (see note Rainer Stern, May 2009). The scenarios have a significant influence on absolute emission levels for the countries that were covered by IIASA GAINS. This suggests that emission changes in countries were no scenarios were available (Armenia, Azerbaijan, Georgia) or where only a projection year baseline is available (all non-EU) may be subject to significant changes as well (but these are quite far from Germany). For future projects it is recommended to make simple and transparent scenarios for these other countries, as well as for International Shipping. The change in emissions from the base year 2005 to the projection year 2010 needs to be interpreted with care. This because some methodology differences between 2005 official emission data as used in the PAREST base year 2005 emission set and GAINS 2010 data exist. It is expected that the emission reduction steps towards 2020 are more realistic.

  5. Spontaneous Emission and Fundamental Limitations on the Signal-to-Noise Ratio in Deep-Subwavelength Plasmonic Waveguide Structures with Gain

    Science.gov (United States)

    Vyshnevyy, Andrey A.; Fedyanin, Dmitry Yu.

    2016-12-01

    Incorporation of gain media in plasmonic nanostructures can give the possibility to compensate for high Ohmic losses in the metal and design truly nanoscale optical components for diverse applications ranging from biosensing to on-chip data communication. However, the process of stimulated emission in the gain medium is inevitably accompanied by spontaneous emission. This spontaneous emission greatly impacts the performance characteristics of deep-subwavelength active plasmonic devices and casts doubt on their practical use. Here we develop a theoretical framework to evaluate the influence of spontaneous emission, which can be applied to waveguide structures of any shape and level of mode confinement. In contrast to the previously developed theories, we take into account that the spectrum of spontaneous emission can be very broad and nonuniform, which is typical for deep-subwavelength structures, where a high optical gain (approximately 1000 cm-1 ) in the active medium is required to compensate for strong absorption in the metal. We also present a detailed study of the spontaneous emission noise in metal-semiconductor active plasmonic nanowaveguides and demonstrate that by using both optical and electrical filtering techniques, it is possible to decrease the noise to a level sufficient for practical applications at telecom and midinfrared wavelengths.

  6. The origin of intermediary metabolism

    Science.gov (United States)

    Morowitz, H. J.; Kostelnik, J. D.; Yang, J.; Cody, G. D.

    2000-01-01

    The core of intermediary metabolism in autotrophs is the citric acid cycle. In a certain group of chemoautotrophs, the reductive citric acid cycle is an engine of synthesis, taking in CO(2) and synthesizing the molecules of the cycle. We have examined the chemistry of a model system of C, H, and O that starts with carbon dioxide and reductants and uses redox couples as the energy source. To inquire into the reaction networks that might emerge, we start with the largest available database of organic molecules, Beilstein on-line, and prune by a set of physical and chemical constraints applicable to the model system. From the 3.5 million entries in Beilstein we emerge with 153 molecules that contain all 11 members of the reductive citric acid cycle. A small number of selection rules generates a very constrained subset, suggesting that this is the type of reaction model that will prove useful in the study of biogenesis. The model indicates that the metabolism shown in the universal chart of pathways may be central to the origin of life, is emergent from organic chemistry, and may be unique.

  7. Knowledge Brokers in Education: How Intermediary Organizations Are Bridging the Gap between Research, Policy and Practice Internationally

    Science.gov (United States)

    Cooper, Amanda; Shewchuk, Samantha

    2015-01-01

    Interest in how to better connect research to policy and practice is gaining momentum globally. Also gaining widespread agreement is the view that intermediary organizations have an important role to play in facilitating multi-stakeholder partnerships between researchers, practitioners and policymakers in order to increase the mobilization of…

  8. Cybersecurity via Intermediaries: Analyzing Security Measurements to Understand Intermediary Incentives and Inform Public Policy

    NARCIS (Netherlands)

    Asghari, H.

    2016-01-01

    Research in the field of information security economics has clarified how attacker and defender incentives affect cybersecurity. It has also highlighted the role of intermediaries in strengthening cybersecurity. Intermediaries are organizations and firms that provide the Internet’s infrastructure an

  9. Cybersecurity via Intermediaries: Analyzing Security Measurements to Understand Intermediary Incentives and Inform Public Policy

    NARCIS (Netherlands)

    Asghari, H.

    2016-01-01

    Research in the field of information security economics has clarified how attacker and defender incentives affect cybersecurity. It has also highlighted the role of intermediaries in strengthening cybersecurity. Intermediaries are organizations and firms that provide the Internet’s infrastructure an

  10. L-band automatic-gain-controlled erbium-doped fiber amplifier utilizing C-band backward-amplified spontaneous emission and electrical feedback monitor.

    Science.gov (United States)

    Shen, Jyi-Lai; Lee, Yueh-Chien; Huang, Chia-Chih

    2009-02-10

    A new L-band automatic-gain-controlled (AGC) erbium-doped fiber amplifier (EDFA) for dense wavelength-division-multiplexing transmission systems is presented, in which a single 1480 nm laser with an internal thermoelectric cooler is used as a primary pump for stable amplification. All C-band amplified spontaneous emission (ASE) is recycled by the secondary pump to enhance the gain efficiency. A fraction of the output signal is used as an electrical feedback monitor for the AGC to improve the gain-clamped (GC) flatness. Experimental results prove that the AGC EDFA has a gain flatness of better than 0.46 dB/40 nm, i.e., below 1.5%, and a higher gain of approximately 36.5 dB compared to that of approximately 35.3 dB for the conventional GC EDFA at -30 dBm input signal power. The best gain flatness of +/-0.25 dB can be achieved over the dynamic range greater than 20 dB. The dynamic range of noise figure is between 6.7 and 7.1. The 3 dB down bandwidth is more than 40 nm. Overall dynamics measurements for the AGC EDFA feedback stabilization have been carried out. The recorded corresponding rise time of 1.565 ms indicates that the system does not exhibit any overshoot of gain or ASE variation due to the signal at the beginning of the pulse.

  11. 42 CFR 480.136 - Disclosure to intermediaries and carriers.

    Science.gov (United States)

    2010-10-01

    ... SERVICES (CONTINUED) QUALITY IMPROVEMENT ORGANIZATIONS ACQUISITION, PROTECTION, AND DISCLOSURE OF QUALITY... practitioner if the QIO and the intermediary or carrier (or CMS if the QIO and the intermediary or...

  12. 77 FR 24713 - Ocean Transportation Intermediary License Revocation

    Science.gov (United States)

    2012-04-25

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant to section...

  13. 77 FR 12584 - Ocean Transportation Intermediary License; Revocation

    Science.gov (United States)

    2012-03-01

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License; Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary license has been revoked pursuant to...

  14. 76 FR 22106 - Ocean Transportation Intermediary License Revocation

    Science.gov (United States)

    2011-04-20

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant to section...

  15. 77 FR 9657 - Ocean Transportation Intermediary License Revocation

    Science.gov (United States)

    2012-02-17

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary license has been revoked pursuant to section 19...

  16. 77 FR 28880 - Ocean Transportation Intermediary License; Revocation

    Science.gov (United States)

    2012-05-16

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License; Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary license has been revoked pursuant to...

  17. 76 FR 41259 - Ocean Transportation Intermediary License; Revocation

    Science.gov (United States)

    2011-07-13

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License; Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary license has been revoked pursuant to...

  18. 77 FR 30532 - Ocean Transportation Intermediary License; Revocation

    Science.gov (United States)

    2012-05-23

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License; Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant...

  19. 75 FR 20998 - Ocean Transportation Intermediary License Revocation

    Science.gov (United States)

    2010-04-22

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant to section...

  20. 76 FR 59128 - Ocean Transportation Intermediary License; Revocation

    Science.gov (United States)

    2011-09-23

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License; Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant...

  1. 77 FR 23720 - Ocean Transportation Intermediary License; Revocation

    Science.gov (United States)

    2012-04-20

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License; Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant...

  2. 75 FR 31440 - Ocean Transportation Intermediary License Revocation

    Science.gov (United States)

    2010-06-03

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant to section...

  3. 76 FR 79682 - Ocean Transportation Intermediary License; Revocation

    Science.gov (United States)

    2011-12-22

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License; Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant...

  4. 75 FR 9603 - Ocean Transportation Intermediary License Revocation

    Science.gov (United States)

    2010-03-03

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary license has been revoked pursuant to section 19...

  5. 76 FR 50216 - Ocean Transportation Intermediary License; Revocation

    Science.gov (United States)

    2011-08-12

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License; Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant...

  6. 76 FR 25692 - Ocean Transportation Intermediary License; Revocation

    Science.gov (United States)

    2011-05-05

    ... From the Federal Register Online via the Government Publishing Office ] FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License; Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant...

  7. 76 FR 60837 - Ocean Transportation Intermediary License Revocation

    Science.gov (United States)

    2011-09-30

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant to section...

  8. 76 FR 62408 - Ocean Transportation Intermediary License; Revocation

    Science.gov (United States)

    2011-10-07

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License; Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant...

  9. 75 FR 76466 - Ocean Transportation Intermediary License Revocation

    Science.gov (United States)

    2010-12-08

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant to section...

  10. 75 FR 25257 - Ocean Transportation Intermediary License Revocation

    Science.gov (United States)

    2010-05-07

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant to section...

  11. 77 FR 5014 - Ocean Transportation Intermediary License; Revocation

    Science.gov (United States)

    2012-02-01

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License; Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary license has been revoked pursuant to...

  12. 76 FR 34993 - Ocean Transportation Intermediary License; Revocation

    Science.gov (United States)

    2011-06-15

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License; Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant...

  13. 75 FR 70674 - Ocean Transportation Intermediary License; Revocation

    Science.gov (United States)

    2010-11-18

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License; Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant...

  14. 77 FR 32116 - Ocean Transportation Intermediary License Revocation

    Science.gov (United States)

    2012-05-31

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant to section...

  15. 76 FR 67189 - Ocean Transportation Intermediary License; Revocation

    Science.gov (United States)

    2011-10-31

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License; Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant...

  16. 76 FR 31963 - Ocean Transportation Intermediary License; Revocation

    Science.gov (United States)

    2011-06-02

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License; Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant...

  17. 76 FR 555 - Ocean Transportation Intermediary License Revocation

    Science.gov (United States)

    2011-01-05

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant to section...

  18. 76 FR 70145 - Ocean Transportation Intermediary License; Revocation

    Science.gov (United States)

    2011-11-10

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License; Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant...

  19. 76 FR 44331 - Ocean Transportation Intermediary License; Revocation

    Science.gov (United States)

    2011-07-25

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License; Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant...

  20. 76 FR 67731 - Ocean Transportation Intermediary License; Revocation

    Science.gov (United States)

    2011-11-02

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License; Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary license has been revoked pursuant to...

  1. 77 FR 13606 - Ocean Transportation Intermediary License Revocation

    Science.gov (United States)

    2012-03-07

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary license has been revoked pursuant to section 19...

  2. 77 FR 18817 - Ocean Transportation Intermediary License; Revocation

    Science.gov (United States)

    2012-03-28

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License; Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant...

  3. 77 FR 1937 - Ocean Transportation Intermediary License; Revocation

    Science.gov (United States)

    2012-01-12

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License; Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant...

  4. 75 FR 17744 - Ocean Transportation Intermediary License Revocation

    Science.gov (United States)

    2010-04-07

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant to section...

  5. 76 FR 7210 - Ocean Transportation Intermediary License; Revocation

    Science.gov (United States)

    2011-02-09

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License; Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant...

  6. 76 FR 78007 - Ocean Transportation Intermediary License; Revocation

    Science.gov (United States)

    2011-12-15

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License; Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary license has been revoked pursuant to...

  7. 77 FR 35386 - Ocean Transportation Intermediary License; Revocation

    Science.gov (United States)

    2012-06-13

    ... From the Federal Register Online via the Government Publishing Office ] FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License; Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant...

  8. 76 FR 28780 - Ocean Transportation Intermediary License; Revocation

    Science.gov (United States)

    2011-05-18

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License; Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant...

  9. 76 FR 16421 - Ocean Transportation Intermediary License; Revocation

    Science.gov (United States)

    2011-03-23

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License; Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant...

  10. 75 FR 72825 - Ocean Transportation Intermediary License; Revocation

    Science.gov (United States)

    2010-11-26

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License; Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant...

  11. 77 FR 27457 - Ocean Transportation Intermediary License Revocation

    Science.gov (United States)

    2012-05-10

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant to section...

  12. 76 FR 65194 - Ocean Transportation Intermediary License; Revocation

    Science.gov (United States)

    2011-10-20

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License; Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant...

  13. 75 FR 11180 - Ocean Transportation Intermediary License Applicants

    Science.gov (United States)

    2010-03-10

    ...-Operating Common Carrier and Ocean Freight Forwarder--Ocean Transportation Intermediary pursuant to section...-Vessel-Operating Common Carrier and Ocean Freight Forwarder Transportation Intermediary Hafen... President (Qualifying Individual). Jose R. Hoppe, President. Ocean Freight Forwarder--Ocean Transportation...

  14. 75 FR 17743 - Ocean Transportation Intermediary License Applicants

    Science.gov (United States)

    2010-04-07

    ...-Operating Common Carrier and Ocean Freight Forwarder--Ocean Transportation Intermediary pursuant to section... Carrier and Ocean Freight Forwarder--Ocean Transportation Intermediary: OWI Specialized, Inc., 840 Apollo... President (Qualifying Individual) Richard Tsai, President. Ocean Freight Forwarder--Ocean Transportation...

  15. 75 FR 76466 - Ocean Transportation Intermediary License Applicants

    Science.gov (United States)

    2010-12-08

    ...-Operating Common Carrier (NVO) and/or Ocean Freight Forwarder (OFF)--Ocean Transportation Intermediary (OTI... Intermediaries, Federal Maritime Commission, Washington, DC 20573. CIL Freight Inc. (NVO & OFF), 1990 Lakeside...

  16. 75 FR 9602 - Ocean Transportation Intermediary License; Applicants

    Science.gov (United States)

    2010-03-03

    ...-Operating Common Carrier and Ocean Freight Forwarder--Ocean Transportation Intermediary pursuant to section..., (Qualifying Individuals), Gloria Comins, Member. Lars Courier, Inc. dba Lars International Freight Forwarders... Ocean Freight Forwarder Transportation Intermediary Applicants Intertrans Express (NY), Inc., 10 East...

  17. 77 FR 42312 - Ocean Transportation Intermediary License; Revocations

    Science.gov (United States)

    2012-07-18

    ... Ocean Transportation Intermediary License; Revocations The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant to... bond. LICENSE NUMBER: 023327N. NAME: G & F West Indies Shipping, Inc. ADDRESS: 1416 Blue Hill...

  18. 76 FR 7210 - Ocean Transportation Intermediary License; Reissuance

    Science.gov (United States)

    2011-02-09

    ... Ocean Transportation Intermediary License; Reissuance Notice is hereby given that the following Ocean Transportation Intermediary license has been reissued by the Federal Maritime Commission pursuant to section 19... to the licensing of Ocean Transportation Intermediaries, 46 CFR part 515. License No....

  19. 77 FR 13605 - Ocean Transportation Intermediary License; Reissuance

    Science.gov (United States)

    2012-03-07

    ... Ocean Transportation Intermediary License; Reissuance Notice is hereby given that the following Ocean Transportation Intermediary licenses have been reissued by the Federal Maritime Commission pursuant to section 19... to the licensing of Ocean Transportation Intermediaries, 46 CFR Part 515. License no....

  20. 76 FR 16421 - Ocean Transportation Intermediary License; Reissuance

    Science.gov (United States)

    2011-03-23

    ... Ocean Transportation Intermediary License; Reissuance Notice is hereby given that the following Ocean Transportation Intermediary licenses have been reissued by the Federal Maritime Commission pursuant to section 19... to the licensing of Ocean Transportation Intermediaries, 46 CFR part 515. License No....

  1. 76 FR 30361 - Ocean Transportation Intermediary License; Reissuance

    Science.gov (United States)

    2011-05-25

    ... No: 2011-12974] FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License; Reissuance Notice is hereby given that the following Ocean Transportation Intermediary licenses have been reissued... Intermediaries, 46 CFR part 515. License No. Name/address Date reissued 001580F Marco Forwarding Co., 8835...

  2. 77 FR 1937 - Ocean Transportation Intermediary License; Reissuance

    Science.gov (United States)

    2012-01-12

    ... Ocean Transportation Intermediary License; Reissuance Notice is hereby given that the following Ocean Transportation Intermediary licenses have been reissued by the Federal Maritime Commission pursuant to section 19... to the licensing of Ocean Transportation Intermediaries, 46 CFR part 515. License No....

  3. 76 FR 28779 - Ocean Transportation Intermediary License; Reissuance

    Science.gov (United States)

    2011-05-18

    ... Ocean Transportation Intermediary License; Reissuance Notice is hereby given that the following Ocean Transportation Intermediary licenses have been reissued by the Federal Maritime Commission pursuant to section 19... to the licensing of Ocean Transportation Intermediaries, 46 CFR part 515. License No....

  4. 76 FR 50216 - Ocean Transportation Intermediary License; Reissuance

    Science.gov (United States)

    2011-08-12

    ... Ocean Transportation Intermediary License; Reissuance Notice is hereby given that the following Ocean Transportation Intermediary licenses have been reissued by the Federal Maritime Commission pursuant to section 19... to the licensing of Ocean Transportation Intermediaries, 46 CFR part 515. License No....

  5. 76 FR 76411 - Ocean Transportation Intermediary License; Reissuance

    Science.gov (United States)

    2011-12-07

    ... Ocean Transportation Intermediary License; Reissuance Notice is hereby given that the following Ocean Transportation Intermediary licenses have been reissued by the Federal Maritime Commission pursuant to section 19... to the licensing of Ocean Transportation Intermediaries, 46 CFR part 515. ] License No....

  6. 75 FR 16483 - Ocean Transportation Intermediary License Applicants

    Science.gov (United States)

    2010-04-01

    ...-Operating Common Carrier and Ocean Freight Forwarder--Ocean Transportation Intermediary pursuant to section...-Operating Common Carrier and Ocean Freight Forwarder--Ocean Transportation Intermediary Post Oak Management... Individual), Michael A. Boaten, Vice President Ocean Freight Forwarder--Ocean Transportation Intermediary LHE...

  7. Towards a Sociology of Intermediary Institutions

    DEFF Research Database (Denmark)

    Kjær, Poul F.

    2014-01-01

    The central ambition of this chapter is to develop dimensions of a theoretical and conceptual framework for the study of intermediary institutions, such as corporatist, neo-corporatist and governance institutions, in the European context. As such, it is designed to create a framework that is capa...

  8. An ontology roadmap for crowdsourcing innovation intermediaries

    OpenAIRE

    Silva, Cândida; Ramos, Isabel

    2014-01-01

    Ontologies have proliferated in the last years, essentially justified by the need of achieving a consensus in the multiple representations of reality inside computers, and therefore the accomplishment of interoperability between machines and systems. Ontologies provide an explicit conceptualization that describes the semantics of the data. Crowdsourcing innovation intermediaries are organizations that mediate the communication and relationship between companies that aspire to solv...

  9. Gaining ground in the modeling of land-use change greenhouse gas emissions associated with biofuel production

    Science.gov (United States)

    Dunn, J.; Mueller, S.; Kwon, H.; Wang, M.; Wander, M.

    2012-12-01

    Land-use change (LUC) resulting from biofuel feedstock production and the associated greenhouse gas (GHG) emissions are a hotly-debated aspect of biofuels. Certainly, LUC GHG emissions are one of the most uncertain elements in life cycle analyses (LCA) of biofuels. To estimate LUC GHG emissions, two sets of data are necessary. First, information on the amount and type of land that is converted to biofuel feedstock production is required. These data are typically generated through application of computable general equilibrium (CGE) models such as Purdue University's Global Trade Analysis Project (GTAP) model. Second, soil carbon content data for the affected land types is essential. Recently, Argonne National Laboratory's Carbon Calculator for Land Use Change from Biofuels Production (CCLUB) has been updated with CGE modeling results that estimate the amount and type of LUC world-wide from production of ethanol from corn, corn stover, miscanthus, and switchgrass (Mueller et al. 2012). Moreover, we have developed state-specific carbon content data, determined through modeling with CENTURY, for the two most dominant soil types in the conterminous 48 U.S. states (Kwon et al. 2012) to enable finer-resolution results for domestic LUC GHG emissions for these ethanol production scenarios. Of the feedstocks examined, CCLUB estimates that LUC GHG emissions are highest for corn ethanol (9.1 g CO2e/MJ ethanol) and lowest for miscanthus (-12 g CO2e/MJ ethanol). We will present key observations from CCLUB results incorporated into Argonne National Laboratory's Greenhouse Gases, Regulated Emissions, and Energy use in Transportation (GREET) model, which is a LCA tool for transportation fuels and advanced vehicle technologies. We will discuss selected issues in this modeling, including the sensitivity of domestic soil carbon emission factors to modeling parameters and assumptions about the fate of harvested wood products. Further, we will discuss efforts to update CCLUB with county

  10. Intermediaries in the Management Process of Innovation

    DEFF Research Database (Denmark)

    Gretzinger, Susanne; Hinz, Holger; Matiaske, Wenzel

    2012-01-01

    Information is a critical resource in innovation processes. SMEs are therefore advised to draw on consulting in innovation processes, as they cannot ensure the necessary information flow internally due to lesser resources. From the strategic point of view, the involvement of intermediaries is acc...... is accompanied by the risk of losing specific knowledge to the business environment. But the other way around: To neglect the integration of consultancies could mean a deficit in the process of information management.......Information is a critical resource in innovation processes. SMEs are therefore advised to draw on consulting in innovation processes, as they cannot ensure the necessary information flow internally due to lesser resources. From the strategic point of view, the involvement of intermediaries...

  11. Intermediaries in the Management Process of Innovation

    DEFF Research Database (Denmark)

    Gretzinger, Susanne; Hinz, Holger; Matiaske, Wenzel

    2012-01-01

    Information is a critical resource in innovation processes. SMEs are therefore advised to draw on consulting in innovation processes, as they cannot ensure the necessary information flow internally due to lesser resources. From the strategic point of view, the involvement of intermediaries is acc...... is accompanied by the risk of losing specific knowledge to the business environment. But the other way around: To neglect the integration of consultancies could mean a deficit in the process of information management.......Information is a critical resource in innovation processes. SMEs are therefore advised to draw on consulting in innovation processes, as they cannot ensure the necessary information flow internally due to lesser resources. From the strategic point of view, the involvement of intermediaries...

  12. Should Governments engage health insurance intermediaries? A comparison of benefits with and without insurance intermediary in a large tax funded community health insurance scheme in the Indian state of Andhra Pradesh.

    Science.gov (United States)

    Nagulapalli, Srikant; Rokkam, Sudarsana Rao

    2015-09-10

    A peculiar phenomenon of engaging insurance intermediaries for government funded health insurance schemes for the poor, not usually found globally, is gaining ground in India. Rajiv Aarogyasri Scheme launched in the Indian state of Andhra Pradesh, is first largest tax funded community health insurance scheme in the country covering more than 20 million poor families. Aarogyasri Health Care Trust (trust), the scheme administrator, transfers funds to hospitals through two routes one, directly and the other through an insurance intermediary. The objective of this paper is to find out if engaging an insurance intermediary has any effect on cost efficiency of the insurance scheme. We used payment data of RAS for the period 2007-12, to find out the influence of insurance intermediary on the two variables, benefit cost ratio defined as benefit payment divided by premium payment, and claim denial ratio defined as benefit payment divided by treatment cost. Relationship between scheme expenditure and number of beds empanelled under the scheme is examined. OLS regression is used to perform all analyses. We found that adding an additional layer of insurance intermediary between the trust and hospitals reduced the benefit cost ratio under the scheme by 12.2% (p-value = 0.06). Every addition of 100 beds under the scheme increases the scheme payments by US$ 0.75 million (p-value insurance and trust modes narrowed down from 2.84% in government hospitals to 0.41% in private hospitals (p-value insurance intermediary has the twin effects of reduction in benefit payments to beneficiaries, and chocking fund flow to government hospitals. The idea of engaging insurance intermediary should be abandoned.

  13. Reputation and Competition among Information Intermediaries

    OpenAIRE

    Lo, P

    2010-01-01

    This paper investigates the e¤ect of competition on the reputation mechanism in the market for information intermediaries such as rating agencies. I use a dynamic model to endogenize the value of reputation to enable comparison of equilibria under di¤erent market structures. Behav- ior is determined in the model by weighing the current rating fee against the future value the rating agency derives from enjoying a good reputa- tion. I show that competition weakens the reputati...

  14. Minimization of the impact of a broad bandwidth high-gain nonlinear preamplifier to the amplified spontaneous emission pedestal of the Vulcan petawatt laser facility.

    Science.gov (United States)

    Musgrave, I O; Hernandez-Gomez, C; Canny, D; Collier, J; Heathcote, R

    2007-10-01

    To generate petawatt pulses using the Vulcan Nd:glass laser requires a broad bandwidth high-gain preamplifier. The preamplifier used is an optical parametric amplifier that provides a total gain of 10(8) in three amplification stages. We report on a detailed investigation of the effect of the Vulcan optical parametric chirped pulse amplification (OPCPA) preamplifier on contrast caused by the amplified spontaneous emission (ASE) pedestal that extends up to 2 ns before the arrival of the main pulse. The contrast after compression is improved to 4x10(8) of the intensity of the main pulse using near-field apertures between the stages of the OPCPA preamplifier. Further reduction of the level of the ASE pedestal can be achieved at the cost of a reduction in amplified bandwidth by solely phosphate glass amplification after initial preamplification rather than a mixed glass amplification scheme.

  15. A sourcebook of methods and procedures for monitoring and reporting anthropogenic greenhouse gas emissions and removals associated with deforestation, gains and losses of carbon stocks in forests remaining forests, and forestation

    NARCIS (Netherlands)

    Achard, F.; Boschetti, L.; Brown, S.; Brady, M.; DeFries, R.; Grassi, G.; Herold, M.; Mollicone, D.; Mora, B.; Pandey, D.; Souza, C.

    2014-01-01

    A sourcebook of methods and procedures for monitoring and reporting anthropogenic greenhouse gas emissions and removals associated with deforestation, gains and losses of carbon stocks in forests remaining forests, and forestation

  16. GOFC-GOLD REDD Sourcebook, COP-18 release - A sourcebook of methods and procedures for monitoring and reporting anthropogenic greenhouse gas emissions and removals associated with deforestation, gains and losses of carbon stocks in forests remaining forests, and forestation

    NARCIS (Netherlands)

    Achard, F.; Brown, S.; Brady, M.; DeFries, R.; Grassi, G.; Herold, M.; Mollicone, D.; Mora, B.; Pandey, D.; Souza, C.

    2012-01-01

    A sourcebook of methods and procedures for monitoring and reporting anthropogenic greenhouse gas emissions and removals associated with deforestation, gains and losses of carbon stocks in forests remaining forests, and forestation

  17. Violet-to-Blue Gain and Lasing from Colloidal CdS Nanoplatelets: Low-Threshold Stimulated Emission Despite Low Photoluminescence Quantum Yield

    Energy Technology Data Exchange (ETDEWEB)

    Diroll, Benjamin T.; Talapin, Dmitri V.; Schaller, Richard D.

    2017-02-13

    Amplified spontaneous emission (ASE) and lasing from solution-processed materials are demonstrated in the challenging violet-to-blue (430–490 nm) spectral region for colloidal nanoplatelets of CdS and newly synthesized core/shell CdS/ZnS nanoplatelets. Despite modest band-edge photoluminescence quantum yields of 2% or less for single excitons, which we show results from hole trapping, the samples exhibit low ASE thresholds. Furthermore, four-monolayer CdS samples show ASE at shorter wavelengths than any reported film of colloidal quantum-confined material. This work underlines that low quantum yields for single excitons do not necessarily lead to a poor gain medium. The low ASE thresholds originate from negligible dispersion in thickness, large absorption cross sections of 2.8 × 10–14 cm–2, and rather slow (150 to 300 ps) biexciton recombination. We show that under higher-fluence excitation, ASE can kinetically outcompete hole trapping. Using nanoplatelets as the gain medium, lasing is observed in a linear optical cavity. This work confirms the fundamental advantages of colloidal quantum well structures as gain media, even in the absence of high photoluminescence efficiency.

  18. Emission Inventory of On-Road Transport in Bangkok Metropolitan Region (BMR Development during 2007 to 2015 Using the GAINS Model

    Directory of Open Access Journals (Sweden)

    Penwadee Cheewaphongphan

    2017-09-01

    Full Text Available Bangkok Metropolitan Region (BMR, including the capital city and five adjacent provinces, constitutes one of the top 10 megacities experiencing serious traffic congestion in the world, leading to air quality problems with significant adverse human health risks. Previously, there have been many operations planned to influence the fuel consumption and emissions from the on-road transport sector in the BMR area. It is necessary to estimate emissions using detailed information in order to thoroughly understand the reason for changes in emission levels and their impact on air quality. This paper aims to determine the successful implementation of energy and air pollution control policies in Thailand through an investigation of the emissions inventory of on-road transport in BMR, including ozone precursors (CO, NOX, Non-methane volatile organic compounds (NMVOCs , greenhouse gases (CO2, CH4, N2O, acidic substances (SO2 and NH3, and particulate matters (PM2.5, PM10, Black Carbon (BC, Organic Carbon (OC during the period from 2007 to 2015, using the Greenhouse Gas and Air Pollution Interactions and Synergies (GAINS model based on the country-specific activity data together with the emission factor from the GAINS-Asia database. This study found that the amount of exhaust emissions over the BMR area in the year 2015 (and the trend during the period from 2007 to 2015 is approximately 139 kt of CO (−7.9%, 103 kt of NOX (−4.1%, 19.9 kt of NMVOC (−6.7%, 15 kt of CO2 (+1.6%, 8.6 kt of CH4 (+6.8%, 0.59 kt of N2O (+1.3%, 0.87 kt of SO2 (−25.8%, 1.1 kt of NH3 (+7.8%, 4.9 kt of PM2.5 (−5.5%, 5.1 kt of PM10 (−7.9%, 3.1 kt of BC (−2.5%, and 1.4 kt of OC (−7.7%. The change in emissions in each pollutant is a result of the more stringent control of fuel and engine standards, the shift in the fuel type used, and the effects of controlling some emissions. Light duty car gasoline fuel is identified as a major contributor of CO, NH3, N2O, and NMVOC, whereas

  19. An Extension Case Study in Institutional Innovation: Microfinance Intermediary Formation

    Science.gov (United States)

    Edelman, Mark A.

    2015-01-01

    An institutional innovation process led by Extension created a statewide microfinance intermediary. The intermediary provides business technical assistance and microloans to entrepreneurs having difficulty securing conventional credit but having workable business plans. The process included (1) gathering indicators of a problem; (2) formation of a…

  20. Procurement of intermediary services: Interpreters in the Netherlands

    NARCIS (Netherlands)

    F. Felsö

    2008-01-01

    This paper reports on the procurement of intermediary services in interpreters to approximately one third of all public clients in The Netherlands. The procurement has lead to a smooth transition from public to a private organization and the new intermediary performs to the satisfaction of its clien

  1. 78 FR 57633 - Ocean Transportation Intermediary License Applicants

    Science.gov (United States)

    2013-09-19

    ... Ocean Transportation Intermediary License Applicants The Commission gives notice that the following applicants have filed an application for an Ocean Transportation Intermediary (OTI) license as a Non-Vessel... OTI license or the Qualifying Individual (QI) for a licensee. Interested persons may contact...

  2. 78 FR 55698 - Ocean Transportation Intermediary License Applicants

    Science.gov (United States)

    2013-09-11

    ... Ocean Transportation Intermediary License Applicants The Commission gives notice that the following applicants have filed an application for an Ocean Transportation Intermediary (OTI) license as a Non-Vessel... OTI license or the Qualifying Individual (QI) for a licensee. Interested persons may contact...

  3. 77 FR 61752 - Ocean Transportation Intermediary License Applicants

    Science.gov (United States)

    2012-10-11

    ... Ocean Transportation Intermediary License Applicants The Commission gives notice that the following applicants have filed an application for an Ocean Transportation Intermediary (OTI) license as a Non-Vessel... existing OTI license or the Qualifying Individual (QI) for a licensee. Interested persons may contact...

  4. 78 FR 27238 - Ocean Transportation Intermediary License Applicants

    Science.gov (United States)

    2013-05-09

    ... Ocean Transportation Intermediary License Applicants The Commission gives notice that the following applicants have filed an application for an Ocean Transportation Intermediary (OTI) license as a Non-Vessel... OTI license or the Qualifying Individual (QI) for a licensee. Interested persons may contact...

  5. 78 FR 40143 - Ocean Transportation Intermediary License Applicants

    Science.gov (United States)

    2013-07-03

    ... Ocean Transportation Intermediary License Applicants The Commission gives notice that the following applicants have filed an application for an Ocean Transportation Intermediary (OTI) license as a Non-Vessel... OTI license or the Qualifying Individual (QI) for a licensee. Interested persons may contact...

  6. 78 FR 20106 - Ocean Transportation Intermediary License Applicants

    Science.gov (United States)

    2013-04-03

    ... Ocean Transportation Intermediary License Applicants The Commission gives notice that the following applicants have filed an application for an Ocean Transportation Intermediary (OTI) license as a Non-Vessel... OTI license or the Qualifying Individual (QI) for a licensee. Interested persons may contact...

  7. 78 FR 43202 - Ocean Transportation Intermediary License Applicants

    Science.gov (United States)

    2013-07-19

    ... Ocean Transportation Intermediary License Applicants The Commission gives notice that the following applicants have filed an application for an Ocean Transportation Intermediary (OTI) license as a Non-Vessel... OTI license or the Qualifying Individual (QI) for a licensee. Interested persons may contact...

  8. 77 FR 56643 - Ocean Transportation Intermediary License Applicants

    Science.gov (United States)

    2012-09-13

    ... Doc No: 2012-22498] FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Applicants... Transportation Intermediary (OTI) license as a Non-Vessel-Operating Common Carrier (NVO) and/or Ocean Freight... given of the filing of applications to amend an existing OTI license or the Qualifying Individual...

  9. Procurement of intermediary services: Interpreters in the Netherlands

    NARCIS (Netherlands)

    Felsö, F.

    2008-01-01

    This paper reports on the procurement of intermediary services in interpreters to approximately one third of all public clients in The Netherlands. The procurement has lead to a smooth transition from public to a private organization and the new intermediary performs to the satisfaction of its

  10. 76 FR 3636 - Ocean Transportation Intermediary License Applicants

    Science.gov (United States)

    2011-01-20

    ... Ocean Transportation Intermediary License Applicants Notice is hereby given that the following...-Operating Common Carrier (NVO) and/or Ocean Freight Forwarder (OFF)--Ocean Transportation Intermediary (OTI... NVO & OFF License. Marine Cargo Line, L.C. dba, Active Freight & Logistics (NVO), One Blue Hill...

  11. 77 FR 49446 - Ocean Transportation Intermediary License Reissuances

    Science.gov (United States)

    2012-08-16

    ... Ocean Transportation Intermediary License Reissuances The Commission gives notice that the following Ocean Transportation Intermediary license has been reissued pursuant to section 40901 of the Shipping...: 1416 Blue Hill Avenue, Boston, MA 02125. Date Reissued: June 26, 2012. Vern W. Hill, Director,...

  12. 78 FR 71611 - Ocean Transportation Intermediary License Revocations and Terminations

    Science.gov (United States)

    2013-11-29

    .... Name: Blue Ocean Logistics Corporation dba B.O. Logistic Corp. Address: 2461 West 205th Street, Unit B... Ocean Transportation Intermediary License Revocations and Terminations The Commission gives notice that the following Ocean Transportation Intermediary licenses have been revoked or terminated for...

  13. 75 FR 6398 - Ocean Transportation Intermediary License Applicants

    Science.gov (United States)

    2010-02-09

    ...-Operating Common Carrier and Ocean Freight Forwarder--Ocean Transportation Intermediary pursuant to section.../Managing Director. Non-Vessel-Operating Common Carrier and Ocean Freight Forwarder Transportation... Ocean Freight Forwarder Transportation Intermediary Applicants (Cont'd): Vortex Worldwide Logistics Corp...

  14. 75 FR 25257 - Ocean Transportation Intermediary License Applicants

    Science.gov (United States)

    2010-05-07

    ...-Operating Common Carrier (NVO) and/or Ocean Freight Forwarder (OFF)--Ocean Transportation Intermediary (OTI... Intermediaries, Federal Maritime Commission, Washington, DC 20573. Atlantic Integrated Freight Inc. (NVO), 19... Individual), Application Type: New NVO License. Direct Service Inc. dba Tiger Freight International...

  15. Contemporary understanding of the intermediary services

    Directory of Open Access Journals (Sweden)

    O.O. Dyma

    2014-03-01

    Full Text Available The aim of the article. One of the most important trends of our time is the rapid growth of service sector in almost all countries, both developed and developing. Attention should be paid to intermediary services, which have specific characteristics – dualistic nature of needs, satisfaction of the producer and final consumer. Today we can observe transformation of the intermediary’s role. Wholesalers are being replaced by logistics companies. Some functions of wholesalers are being fulfilled by manufacturers and retailers. Retailers, manufacturers and service companies are expanding their sphere of influence and are focusing their efforts on integration and coordination of participants in the value chain to ensure maximum satisfaction of consumer needs. Therefore, we need to make a critical analysis of the category of «intermediary services» and represent the author's understanding of the category of «intermediary services». The results of the analysis. Exploring a wide range of research papers devoted to the marketing of services allows us to conclude that it is difficult to distinguish between goods and services. In domestic and foreign literature, there are many definitions of services which are substantially different. Some definitions attempt to cover most of the features of services, while others can be quite vague, treating the «service» as «a specific type of product». The variation in the definition of the «service» may be due to differences in approaches to understanding the «service». So we have identified four different approaches to the understanding of the service category, taking into account the whole process of consumption of services, ranging from the emergence of the need for a particular service to the satisfaction of this need. The analysis has distinguished the following main characteristics present in the definitions of the «service»: process / result, consumer satisfaction, immateriality, tangibility

  16. Detecting Intermediary Hosts by TCP Latency Measurements

    Science.gov (United States)

    Singh, Gurvinder; Eian, Martin; Willassen, Svein Y.; Mjølsnes, Stig Fr.

    Use of intermediary hosts as stepping stones to conceal tracks is common in Internet misuse. It is therefore desirable to find a method to detect whether the originating party is using an intermediary host. Such a detection technique would allow the activation of a number of countermeasures that would neutralize the effects of misuse, and make it easier to trace a perpetrator. This work explores a new approach in determining if a host communicating via TCP is the data originator or if it is acting as a mere TCP proxy. The approach is based on measuring the inter packet arrival time at the receiving end of the connection only, and correlating the observed results with the network latency between the receiver and the proxy. The results presented here indicate that determining the use of a proxy host is possible, if the network latency between the originator and proxy is larger than the network latency between the proxy and the receiver. We show that this technique has potential to be used to detect connections were data is sent through a TCP proxy, such as remote login through TCP proxies, or rejecting spam sent through a bot network.

  17. The Functions of Sourcing Intermediaries in Global Supply Risk Management

    DEFF Research Database (Denmark)

    Vedel, Mette; Ellegaard, Chris

    The aim of this work-in-progress paper is to uncover the supply risk management functions performed by sourcing intermediaries. The purchasing and supply chain management literature, including the part of it concerned with supply risk, pays little attention to sourcing intermediaries....... But the fields of marketing and international business have investigated the intermediary including its high supply risk reducing potentials, suggesting that this supply chain entity may be highly relevant to supply risk management. In order to get a better understanding of the supply risk reducing properties...... of sourcing intermediaries, we perform a study of the Danish clothing industry. The study incorporate interviews across a range of functions and companies in this industry including retailers, producers, suppliers, and various types of intermediaries. We contribute by coupling the supply risk management...

  18. The World Intermediary Liability Map: Charting the Online Intermediary Liability Conundrum

    OpenAIRE

    2016-01-01

    Whether and when access providers and communications platforms like Google, Twitter and Facebook are liable for their users’ online activities is a key factor that effects innovation and free speech. There are emerging legal, policy and ethical issues facing online intermediaries. Unfortunately, with globalized online service providers operating across the world in an interdependent digital environment, inconsistencies across different regimes generate legal uncertainties that undermine both ...

  19. The Functions of Sourcing Intermediaries in Global Supply Risk Management

    DEFF Research Database (Denmark)

    Vedel, Mette; Ellegaard, Chris

    The aim of this work-in-progress paper is to uncover the supply risk management functions performed by sourcing intermediaries. The purchasing and supply chain management literature, including the part of it concerned with supply risk, pays little attention to sourcing intermediaries....... But the fields of marketing and international business have investigated the intermediary including its high supply risk reducing potentials, suggesting that this supply chain entity may be highly relevant to supply risk management. In order to get a better understanding of the supply risk reducing properties...... in the supply risk management literature and as a managerial option that can effectively alleviate certain kinds of supply risk....

  20. Widening the scope? How intermediary actors can shape energy consumption

    DEFF Research Database (Denmark)

    Maneschi, Davide

    2013-01-01

    , socio-technical systems, governance in the water sector and, although limitedly, in the explanation of aspects related to consumption and energy use. Building on the framework given by the review, the paper presents a case study to provide a real-life example of how intermediaries can favor the more...... – influence energy consumption. This paper presents a review of the literature on intermediaries, providing an overview of their roles and contextualizing their functions in energy efficiency improvements. The review shows how the concept of intermediaries has been used in research dealing with innovation...

  1. 7 CFR 4274.307 - Eligibility requirements-Intermediary.

    Science.gov (United States)

    2010-01-01

    ..., such operations as producing, purchasing, marketing, processing, or other activities aimed at improving the income of their members as producers or their purchasing power as consumers. (b) The intermediary...

  2. Develop A Framework for Selection of Intermediary in Marketing Channel

    Directory of Open Access Journals (Sweden)

    Hamid Reza Irani

    2011-03-01

    Full Text Available This study seeks to examine how a company can select the best intermediary for itsMarketing channels with minimum of criteria and time. A theoretical framework is proposed basedon the most important tasks of intermediary and the criteria to measure them. There are four basictasks and thirty criteria in three independent levels. Subsequently, an exploratory case study inIranian Food industry is described to illustrate the value of the framework. It is possible to apply thetheoretical framework to select the intermediary for any industry or country. However, there mightbe possible location-specific or industry-specific limitations. Moreover, the framework has provedto be useful in improving the selection of the intermediary in marketing channel. This is a notableand promising side-effect of the exploratory study, at least from a managerial point of view.

  3. Doing things by halves: on intermediary global institutional proposals

    Directory of Open Access Journals (Sweden)

    Luke Ulaş

    2016-06-01

    Full Text Available Various cosmopolitan theorists offer global institutional prescriptions intended to be understood as residing conceptually between a system of separate domestic states and a federal world state. In this article I assess such ‘intermediary’ models, and claim that they are an unprofitable mix of idealism and misplaced pragmatism: they are ostensibly illustrations of future-oriented institutional ideals, and yet they are infused with concessions to present-day reality. In some cases, the concession is merely rhetorical: we are offered world state visions in intermediary clothing. In other cases, the concession is substantive, with the ironic result that intermediary models are in fact less feasible than the idea of a world state which intermediary theorists quickly reject. The overall aim of the argument is not to fully defend the idea of a world state, but rather only to demonstrate that there are reasons, from a cosmopolitan perspective, to consider a world state superior to intermediary models.

  4. 78 FR 49752 - Ocean Transportation Intermediary License Revocations and Terminations

    Science.gov (United States)

    2013-08-15

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Revocations and Terminations The Commission gives notice that... valid bond. License No.: 018716N. Name: Transporte Medrano Inc. Address: 134 North Franklin...

  5. 76 FR 72409 - Ocean Transportation Intermediary License Revocation

    Science.gov (United States)

    2011-11-23

    ... [Federal Register Volume 76, Number 226 (Wednesday, November 23, 2011)] [Notices] [Page 72409] [FR Doc No: 2011-30244] FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Revocation The Federal Maritime Commission hereby gives notice that the following Ocean...

  6. 75 FR 29547 - Ocean Transportation Intermediary License Revocation

    Science.gov (United States)

    2010-05-26

    ... [Federal Register Volume 75, Number 101 (Wednesday, May 26, 2010)] [Notices] [Page 29547] [FR Doc No: 2010-12675] FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation...

  7. 75 FR 3467 - Ocean Transportation Intermediary License; Applicants

    Science.gov (United States)

    2010-01-21

    ...-Operating Common Carrier and Ocean Freight Forwarder--Ocean Transportation Intermediary pursuant to section...). Patrick Turner, Member Manager. Non-Vessel-Operating Common Carrier and Ocean Freight Forwarder..., Officer: Rajiv Dixit, President. (Qualifying Officer) Ocean Freight Forwarder--Ocean Transportation...

  8. 76 FR 71034 - Ocean Transportation Intermediary License; Applicants

    Science.gov (United States)

    2011-11-16

    ...-Operating Common Carrier (NVO) and/or Ocean Freight Forwarder (OFF)--Ocean Transportation Intermediary (OTI.... Application Type: Name Change. Abco International Freight (USA) Inc. dba Abco Logistics (NVO), 9420 Telstar...

  9. 75 FR 42446 - Ocean Transportation Intermediary License Applicants

    Science.gov (United States)

    2010-07-21

    ...-Operating Common Carrier (NVO) and/or Ocean Freight Forwarder (OFF)--Ocean Transportation Intermediary (OTI...), Chuck Sun, Vice President/Secretary. Application Type: New NVO & OFF License. E-Freight Solutions Inc...

  10. 78 FR 33841 - Ocean Transportation Intermediary License Applicants

    Science.gov (United States)

    2013-06-05

    ... Transportation Intermediary (OTI) license as a Non-Vessel-Operating Common Carrier (NVO) and/or Ocean Freight Forwarder (OFF) pursuant to section 19 of the Shipping Act of 1984 (46 U.S.C. 40101). Notice is also given...

  11. 75 FR 69080 - Ocean Transportation Intermediary License Applicants

    Science.gov (United States)

    2010-11-10

    ...-Operating Common Carrier (NVO), and/or Ocean Freight Forwarder (OFF)--Ocean Transportation Intermediary (OTI... License. Freight Forwarder International, Inc. (OFF), 200 Crofton Road, Building 14-A, Kenner, LA 70062...

  12. Overcoming Intermediary Bias Through the Use of Social Media Intelligence

    Science.gov (United States)

    2015-05-23

    forces process the large amounts of rich data that social media networks collect through multiple means. The nature of the data set and the...Overcoming Intermediary Bias Through the Use of Social Media Intelligence A Monograph by MAJ Damian Ryan Taafe-McMenamy United States...Intermediary Bias Through the Use of Social Media Intelligence 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S

  13. Beyond Gatekeeping: The Normative Responsibility of Internet Intermediaries

    OpenAIRE

    Thompson, M

    2015-01-01

    This paper puts forward a normative approach to the responsibility of Internet intermediaries for third-party content they host. It argues that, in thinking about intermediary liability, our focus should be, rather than on the outcomes of intermediaries’ decisions, on their responsibility towards the reasoning processes in reaching these. What is necessary is a framework that, at the same time that it attaches responsibilities to such decisions, creates a cushioning system for their making, a...

  14. Intermediaries in Trust: Indirect Reciprocity, Incentives, and Norms

    Directory of Open Access Journals (Sweden)

    Giangiacomo Bravo

    2015-01-01

    Full Text Available Any trust situation involves a certain amount of risk for trustors that trustees could abuse. In some cases, intermediaries exist who play a crucial role in the exchange by providing reputational information. To examine under what conditions intermediary opinion could have a positive impact on cooperation, we designed two experiments based on a modified version of the investment game where intermediaries rated the behaviour of trustees under various incentive schemes and different role structures. We found that intermediaries can increase trust if there is room for indirect reciprocity between the involved parties. We also found that the effect of monetary incentives and social norms cannot be clearly separable in these situations. If properly designed, monetary incentives for intermediaries can have a positive effect. On the one hand, when intermediary rewards are aligned with the trustor’s interest, investments and returns tend to increase. On the other hand, fixed monetary incentives perform less than any other incentive schemes and endogenous social norms in ensuring trust and fairness. These findings should make us reconsider the mantra of incentivization of social and public conventional policy.

  15. DEVELOPMENT OF INSURANCE INTERMEDIARIES IN THE DEVELOP EUROPEAN COUNTRIES

    Directory of Open Access Journals (Sweden)

    D. Nesterova

    2016-03-01

    Full Text Available The article presents theoretical and practical approaches in determining the features of insurance intermediation. It characterizes the traditional model of selling insurance products and modern multi-channel sales model of insurance services. It identifies the main legal acts that regulate the activities of insurance intermediaries in the European Union. In the article analyzed the activity of insurance intermediaries in the EU. The main channels of sales of insurance products are determined. The shares of premiums of insurance intermediaries in the volume of insurance premiums and in the GDP of the insurance markets of European countries are defined. The number of employees who are involved in insurance intermediary in the European countries is investigated. The European experience of insurance agents and insurance brokers in non-life insurance and life insurance is considered. It's analyzed the activity of insurance brokers in the Ukraine. The main trends and problems of the development of insurance intermediaries in the insurance market of Ukraine are defined.

  16. A Framework for Selection of Intermediary in Marketing Channel

    Directory of Open Access Journals (Sweden)

    Hamid Reza Irani

    2011-10-01

    Full Text Available Purpose – This study seeks to examine how company can select the best intermediary for its Marketing channels with minimum of criteria and time. Design/methodology/approach – A theoretical framework is proposed based on the most
    importance tasks of intermediary and criteria for measuring them. There are four basic tasks and 30 criteria in three independent levels. Subsequently, an exploratory case study in Iranian Food industry is described that illustrates the value of the framework. Findings – It is possible, for example, to apply the theoretical framework to select the intermediary for any industry or any country. Research limitations/implications – The study has possible location- and industry-specific limitations.
    Originality/value – Moreover, the framework has proven to be useful in improving the selection of the intermediary in marketing channel. This is a notable and promising side-effect of the exploratory study, at least from a managerial point of view.
    Keywords: Marketing channel, Distribution channel, Channel design, Selection criteria, channel members, Intermediary selection

  17. The privacy role of information intermediaries through self-regulation

    Directory of Open Access Journals (Sweden)

    Tatevik Sargsyan

    2016-12-01

    Full Text Available Through qualitative analysis of the policies of two major global information intermediaries — Google and Microsoft — and related case studies, this paper demonstrates a that intermediaries’ participation in self-regulatory programmes and implementation of privacy principles does not necessarily translate into meaningful privacy safeguards for users in the face of growing private surveillance capacity; and b that within the EU and US self-regulatory frameworks, information intermediaries have discretionary power to set their policies and practices prioritising strategic interests over privacy commitments. Discussions in this paper complement existing studies on the implementation of privacy principles stipulated in Fair Information Practices (FIPs by enhancing understanding about the role of information intermediaries in defining privacy conditions of users within self-regulation.

  18. Addressing barriers to eco-innovation: Exploring the finance mobilisation functions of institutional innovation intermediaries

    NARCIS (Netherlands)

    Polzin, Friedemann; Flotow, von Paschen; Klerkx, L.W.A.

    2016-01-01

    This research article explores the role of institutional innovation intermediaries in accelerating the commercialisation of (clean) technologies. Drawing on the finance and innovation intermediaries literatures, we show that financial barriers to eco-innovation can be partly overcome by particular

  19. Theorizing Uptake and Knowledge Mobilization: A Case for Intermediary Genre

    Science.gov (United States)

    Tachino, Tosh

    2012-01-01

    Recent scholarship in genre studies has extended its focus from studying single genres to multiple genres, as well as how these genres interact with one another. This essay seeks to contribute to this growing scholarship by adding a new concept, "intermediary genre". That is, a genre that facilitates the "uptake" of a genre by another genre. This…

  20. Advertising and knowledge intermediaries : Managing the ethical challenges of intangibles

    NARCIS (Netherlands)

    Millar, CCJM; Choi, CJ

    2003-01-01

    In today's business environment, the knowledge-based society, globalisation, and information and communication technologies (ICT) have increased the role of "intangible" values of assets and resources for all industries. As a result there is an increased role for knowledge intermediaries; one of the

  1. 76 FR 79682 - Ocean Transportation Intermediary License; Applicants

    Science.gov (United States)

    2011-12-22

    ... Ocean Transportation Intermediary License; Applicants Notice is hereby given that the following applicants have filed with the Federal Maritime Commission an application for a license as a Non-Vessel...). Notice is also hereby given of the filing of applications to amend an existing OTI license or...

  2. 76 FR 30360 - Ocean Transportation Intermediary License; Applicants

    Science.gov (United States)

    2011-05-25

    ...] [FR Doc No: 2011-12969] FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License... Commission an application for a license as a Non-Vessel-Operating Common Carrier (NVO) and/or Ocean Freight... applications to amend an existing OTI license or the Qualifying Individual (QI) for a license....

  3. 76 FR 7209 - Ocean Transportation Intermediary License; Applicants

    Science.gov (United States)

    2011-02-09

    ... Ocean Transportation Intermediary License; Applicants Notice is hereby given that the following applicants have filed with the Federal Maritime Commission an application for a license as a Non-Vessel...). Notice is also hereby given of the filing of applications to amend an existing OTI license or...

  4. 76 FR 33757 - Ocean Transportation Intermediary License; Applicants

    Science.gov (United States)

    2011-06-09

    ... Ocean Transportation Intermediary License; Applicants Notice is hereby given that the following applicants have filed with the Federal Maritime Commission an application for a license as a Non-Vessel...). Notice is also hereby given of the filing of applications to amend an existing OTI license or...

  5. 77 FR 6563 - Ocean Transportation Intermediary License; Applicants

    Science.gov (United States)

    2012-02-08

    ... Ocean Transportation Intermediary License; Applicants Notice is hereby given that the following applicants have filed with the Federal Maritime Commission an application for a license as a Non-Vessel...). Notice is also hereby given of the filing of applications to amend an existing OTI license or...

  6. 76 FR 76411 - Ocean Transportation Intermediary License; Applicants

    Science.gov (United States)

    2011-12-07

    ... Ocean Transportation Intermediary License; Applicants Notice is hereby given that the following applicants have filed with the Federal Maritime Commission an application for a license as a Non-Vessel...). Notice is also hereby given of the filing of applications to amend an existing OTI license or...

  7. 76 FR 62407 - Ocean Transportation Intermediary License; Applicants

    Science.gov (United States)

    2011-10-07

    ... Ocean Transportation Intermediary License; Applicants Notice is hereby given that the following applicants have filed with the Federal Maritime Commission an application for a license as a Non-Vessel...). Notice is also hereby given of the filing of applications to amend an existing OTI license or...

  8. 76 FR 78007 - Ocean Transportation Intermediary License; Applicants

    Science.gov (United States)

    2011-12-15

    ... Ocean Transportation Intermediary License; Applicants Notice is hereby given that the following applicants have filed with the Federal Maritime Commission an application for a license as a Non-Vessel...). Notice is also hereby given of the filing of applications to amend an existing OTI license or...

  9. 77 FR 39707 - Ocean Transportation Intermediary License; Applicants

    Science.gov (United States)

    2012-07-05

    ... No: 2012-16473] FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License; Applicants... application for a license as a Non-Vessel-Operating Common Carrier (NVO) and/or Ocean Freight Forwarder (OFF.... 40101). Notice is also hereby given of the filing of applications to amend an existing OTI license...

  10. 76 FR 28778 - Ocean Transportation Intermediary License; Applicants

    Science.gov (United States)

    2011-05-18

    ... Ocean Transportation Intermediary License; Applicants Notice is hereby given that the following applicants have filed with the Federal Maritime Commission an application for a license as a Non-Vessel...). Notice is also hereby given of the filing of applications to amend an existing OTI license or...

  11. 77 FR 1936 - Ocean Transportation Intermediary License; Applicants

    Science.gov (United States)

    2012-01-12

    ... Ocean Transportation Intermediary License; Applicants Notice is hereby given that the following applicants have filed with the Federal Maritime Commission an application for a license as a Non-Vessel...). Notice is also hereby given of the filing of applications to amend an existing OTI license or...

  12. Workforce Intermediaries: Powering Regional Economies in the New Century

    Science.gov (United States)

    Fischer, David Jason

    2005-01-01

    This report looks at three very distinct intermediary organizations--The Reinvestment Fund, a social-purpose lender and financier of community and economic revitalization in Philadelphia; Wisconsin Regional Training Partnership, a labor/management partnership in Milwaukee; and the Seattle Jobs Initiative, an agency that began its operations within…

  13. Theorizing Uptake and Knowledge Mobilization: A Case for Intermediary Genre

    Science.gov (United States)

    Tachino, Tosh

    2012-01-01

    Recent scholarship in genre studies has extended its focus from studying single genres to multiple genres, as well as how these genres interact with one another. This essay seeks to contribute to this growing scholarship by adding a new concept, "intermediary genre". That is, a genre that facilitates the "uptake" of a genre by…

  14. Universities as Intermediaries: Impact Investing and Social Entrepreneurship

    Science.gov (United States)

    Tekula, Rebecca; Shah, Archana; Jhamb, Jordan

    2015-01-01

    Metropolitan universities are well poised in communities to be intermediaries among various actors involved in social innovation. Pace University established one of the first institutes on social entrepreneurship. Its unique position at the university level allows programming to transcend certain institutional challenges. The emerging field of…

  15. 77 FR 22625 - Intermediary Lending Pilot (ILP) Program

    Science.gov (United States)

    2012-04-16

    .../intermediary-lending-pilot . Application submission rules: Complete applications must be received by the Chief... considered. Due to the required irradiation of regular mail delivered through the U.S. Postal Service prior... Selection (SBA Form 2417) for specific requirements. Applications sent via email or by facsimile will not be...

  16. Metabolic interrelationships software application: Interactive learning tool for intermediary metabolism

    NARCIS (Netherlands)

    A.J.M. Verhoeven (Adrie); M. Doets (Mathijs); J.M.J. Lamers (Jos); J.F. Koster (Johan)

    2005-01-01

    textabstractWe developed and implemented the software application titled Metabolic Interrelationships as a self-learning and -teaching tool for intermediary metabolism. It is used by undergraduate medical students in an integrated organ systems-based and disease-oriented core curriculum, which start

  17. Outsourcing HR Services: The Role of Human Resource Intermediaries

    Science.gov (United States)

    Kock, Henrik; Wallo, Andreas; Nilsson, Barbro; Hoglund, Cecilia

    2012-01-01

    Purpose: In this article, the area of interest is an emerging type of organisation called human resource intermediaries (HRIs), which focus on delivering human resource (HR) services to public sector organisations and private companies. The purpose of this article is, thus, to explore HRIs as deliverers of HR services. More specifically, the…

  18. Metabolic interrelationships software application: Interactive learning tool for intermediary metabolism

    NARCIS (Netherlands)

    A.J.M. Verhoeven (Adrie); M. Doets (Mathijs); J.M.J. Lamers (Jos); J.F. Koster (Johan)

    2005-01-01

    textabstractWe developed and implemented the software application titled Metabolic Interrelationships as a self-learning and -teaching tool for intermediary metabolism. It is used by undergraduate medical students in an integrated organ systems-based and disease-oriented core curriculum, which

  19. 75 FR 39529 - Ocean Transportation Intermediary License Applicants

    Science.gov (United States)

    2010-07-09

    ... & NVO License Blue Ocean Freight, Inc. dba Seaship Line (OFF & NVO), 250 Valley Street, 2F, Providence..., Secretary, Application Type: Add NVO Service and Trade Name Change Blue Ocean Shipping, Inc. dba Advanced... Ocean Transportation Intermediary License Applicants Notice is hereby given that the...

  20. 76 FR 56759 - Ocean Transportation Intermediary License; Applicants

    Science.gov (United States)

    2011-09-14

    ...-Operating Common Carrier (NVO) and/or Ocean Freight Forwarder (OFF)--Ocean Transportation Intermediary (OTI... Partnership, dba Villamayor Freight Forwarder (OFF), 8002 N. Oak Trafficway, Suite 108, Kansas City, MO 64118... Change. New Star Freight, Inc. dba American Freight Solutions (NVO & OFF), 7354 Country Fair Drive...

  1. Universities' Intermediary Role in the "Design for Sustainability" Field

    Science.gov (United States)

    Küçüksayraç, Elif; Wever, Renee; Brezet, Han

    2017-01-01

    Purpose: This paper aims to investigate the intermediary role of universities in spreading design for sustainability into industry. Design/methodology/approach: Three case studies were undertaken on Delft University of Technology, Design for Sustainability Program from The Netherlands; a center on sustainable consumption and production; and Prof.…

  2. Evaluating the Role of Intermediaries in the Electronic Value Chain.

    Science.gov (United States)

    Janssen, Marijn; Sol, Henk G.

    2000-01-01

    Presents a business engineering methodology that supports the identification of electronic intermediary roles in the electronic value chain. The goal of this methodology is to give stakeholders insight into their current, and possible alternative, situations by means of visualization, to evaluate the added value of business models using…

  3. Universities' Intermediary Role in the "Design for Sustainability" Field

    Science.gov (United States)

    Küçüksayraç, Elif; Wever, Renee; Brezet, Han

    2017-01-01

    Purpose: This paper aims to investigate the intermediary role of universities in spreading design for sustainability into industry. Design/methodology/approach: Three case studies were undertaken on Delft University of Technology, Design for Sustainability Program from The Netherlands; a center on sustainable consumption and production; and Prof.…

  4. Advertising and knowledge intermediaries : Managing the ethical challenges of intangibles

    NARCIS (Netherlands)

    Millar, CCJM; Choi, CJ

    2003-01-01

    In today's business environment, the knowledge-based society, globalisation, and information and communication technologies (ICT) have increased the role of "intangible" values of assets and resources for all industries. As a result there is an increased role for knowledge intermediaries; one of the

  5. Advertising and knowledge intermediaries : Managing the ethical challenges of intangibles

    NARCIS (Netherlands)

    Millar, CCJM; Choi, CJ

    2003-01-01

    In today's business environment, the knowledge-based society, globalisation, and information and communication technologies (ICT) have increased the role of "intangible" values of assets and resources for all industries. As a result there is an increased role for knowledge intermediaries; one of

  6. The function of intermediaries in collaborative innovation processes

    DEFF Research Database (Denmark)

    Hermann, Roberto Rivas; Mosgaard, Mette; Kerndrup, Søren

    2016-01-01

    projects related to cleaner technologies and small vessels are an understudied subject. The case study of a Danish small island ferry retrofit shows that intermediaries are important to stage the collaboration between actors. They can provide functions to the incipient network as foresight, brokering...

  7. Evaluating the Role of Intermediaries in the Electronic Value Chain.

    Science.gov (United States)

    Janssen, Marijn; Sol, Henk G.

    2000-01-01

    Presents a business engineering methodology that supports the identification of electronic intermediary roles in the electronic value chain. The goal of this methodology is to give stakeholders insight into their current, and possible alternative, situations by means of visualization, to evaluate the added value of business models using…

  8. Financial Intermediaries and Economic Growth: The Nigerian Evidence

    Directory of Open Access Journals (Sweden)

    Oba Efayena

    2014-06-01

    Full Text Available This study seeks to examine the role of financial intermediaries and to find out whether financial intermediaries impact on economic growth in Nigeria. The study adopts the Harrod-Domar growth model which states that economic growth will proceed at the rate which society can mobilize domestic savings resources coupled with the productivity of the investment. The study employed the use of secondary data for the period 1981 to 2011 which were sourced from the CBN statistical bulletin. Nigerian banks being the dominant financial intermediaries, loans credits and advances from banks were used as proxy for the independent variable. Gross domestic product (GDP was used as proxy for economic growth. Using the technique of correlation analysis in determining the association between loan credits and advances, and the GDP, the study reveals a relatively high positive correlation between financial intermediaries and economic growth in the Nigerian economy. The study recommends that Nigerian banks should lend higher proportion of their loanable funds to small and medium enterprises (SMEs and should invest in information technology and human capital.

  9. European intermediary liability in copyright: A tort-based analysis

    NARCIS (Netherlands)

    Angelopoulos, C.J.

    2016-01-01

    With the adoption and subsequent national implementation of the E-Commerce Directive’s safe harbour regime, the architecture set up in Europe for the civil liability of internet intermediaries for the copyright infringements of others has become two-tiered: at a first stage, it is necessary to exami

  10. Outsourcing HR Services: The Role of Human Resource Intermediaries

    Science.gov (United States)

    Kock, Henrik; Wallo, Andreas; Nilsson, Barbro; Hoglund, Cecilia

    2012-01-01

    Purpose: In this article, the area of interest is an emerging type of organisation called human resource intermediaries (HRIs), which focus on delivering human resource (HR) services to public sector organisations and private companies. The purpose of this article is, thus, to explore HRIs as deliverers of HR services. More specifically, the…

  11. Designing for acceptance: exchange design for electronic intermediaries

    NARCIS (Netherlands)

    Fielt, E.J.

    2006-01-01

    Electronic business has brought many success stories as well as failures. Intermediaries are a particularly interesting application domain: on the one hand, they are given opportunities by electronic business to reinvent their value logic, while on the other they are threatened by opportunities for

  12. Widening the scope? How intermediary actors can shape energy consumption

    DEFF Research Database (Denmark)

    Maneschi, Davide

    2013-01-01

    This paper deals with energy consumption in the residential sector and with the implementation of measures to reduce it. While most research dealing with energy consumption has targeted factors and drivers at the individual user level, more recent works have highlighted collective aspects...... of (energy) consumption, both to explain the resilience of consumption patterns and to identify leverage points for the reduction of energy use. One understudied aspect of this discussion is the way “intermediary” actors – those actors who are neither policy makers, nor users, nor energy providers...... – influence energy consumption. This paper presents a review of the literature on intermediaries, providing an overview of their roles and contextualizing their functions in energy efficiency improvements. The review shows how the concept of intermediaries has been used in research dealing with innovation...

  13. Cooperation with Market Intermediaries in the Chinese Market

    OpenAIRE

    Qian, Danjun

    2014-01-01

    This bachelor’s thesis was commissioned by a Finnish hospitality company. The purpose of this study was to improve the cooperation between the company and its marketing intermediaries in the Chinese outbound travel market. The products of the company are promoted, distributed and sold in the Chinese outbound market mostly through tour operators and travel agencies. Therefore, finding out how to build a better relationship with them is essential for the company. The method used in this study ...

  14. The law and economics of intermediaries of personal information

    OpenAIRE

    Luchetta, Giacomo

    2013-01-01

    This paper explores a class of firms: the intermediaries of personal information. In the economics of personal information, scarcity is no longer the only, and foremost, determinant of value. The most important determinant of value becomes connection. Adapting what Gervais claims to be the first law of an information-flooded cloud-modelled economy, value is not derived from scarcity but rather from the fact that those who value it most will find it. Personal information is the raw material to...

  15. Intermediary cooperative associations and the institutionalization of participative work practices

    DEFF Research Database (Denmark)

    Sørensen, Ole Henning; Doellgast, Virginia; Bojesen, Anders

    2015-01-01

    of the Centre for the Development of Human Resources and Quality Management (SCKK), a social partnership-based organization that funds workplace development Projects at state workplaces, and of nine participative development projects that received financial and logistical support from the SCKK. These projects...... increased union and management commitment to partnership-based approaches to problem-solving, despite their ambiguous results for both groups. This suggests that intermediary cooperative associations help to enhance the normative legitimacy of participative work practices through the provision of resources...... and ‘best practice’ management approaches....

  16. Travel intermediaries and responsibility for compliance with EU travel law : A scattered legal picture

    NARCIS (Netherlands)

    de Vries, Anne

    2016-01-01

    Travel intermediaries, commonly known as travel agencies, are important and well-known actors in the travel sector and online travel agencies such as Expedia, Booking.com and AirBnB are booming. Although intermediaries obviously bring clear benefits for contracting parties, they also complicate the

  17. The emergence and functioning of innovation intermediaries in maturing innovation systems: the case of Chile

    NARCIS (Netherlands)

    Klerkx, L.W.A.; Álvarez, R.; Campusano, R.

    2015-01-01

    Innovation intermediaries that build linkages in innovation systems are reportedly needed in many Latin American countries and other developing and emerging countries around the world that are said to have an immature innovation system. This study analyses the types of innovation intermediaries that

  18. Travel intermediaries and responsibility for compliance with EU travel law : A scattered legal picture

    NARCIS (Netherlands)

    de Vries, Anne

    2016-01-01

    Travel intermediaries, commonly known as travel agencies, are important and well-known actors in the travel sector and online travel agencies such as Expedia, Booking.com and AirBnB are booming. Although intermediaries obviously bring clear benefits for contracting parties, they also complicate the

  19. Addressing barriers to eco-innovation: Exploring the finance mobilisation functions of institutional innovation intermediaries

    NARCIS (Netherlands)

    Polzin, Friedemann; Flotow, von Paschen; Klerkx, L.W.A.

    2016-01-01

    This research article explores the role of institutional innovation intermediaries in accelerating the commercialisation of (clean) technologies. Drawing on the finance and innovation intermediaries literatures, we show that financial barriers to eco-innovation can be partly overcome by particular f

  20. The emergence and functioning of innovation intermediaries in maturing innovation systems: the case of Chile

    NARCIS (Netherlands)

    Klerkx, L.W.A.; Álvarez, R.; Campusano, R.

    2015-01-01

    Innovation intermediaries that build linkages in innovation systems are reportedly needed in many Latin American countries and other developing and emerging countries around the world that are said to have an immature innovation system. This study analyses the types of innovation intermediaries that

  1. Addressing barriers to eco-innovation: Exploring the finance mobilisation functions of institutional innovation intermediaries

    NARCIS (Netherlands)

    Polzin, Friedemann; Flotow, von Paschen; Klerkx, L.W.A.

    2016-01-01

    This research article explores the role of institutional innovation intermediaries in accelerating the commercialisation of (clean) technologies. Drawing on the finance and innovation intermediaries literatures, we show that financial barriers to eco-innovation can be partly overcome by particular f

  2. The Modern Cult of Efficiency: Intermediary Organizations and the New Scientific Management

    Science.gov (United States)

    Trujillo, Tina

    2014-01-01

    This article analyzes one intermediary organization. It draws on critical policy studies to frame the agency's behaviors amid a discourse of managerialism in the public sector, and critical studies of education markets to explain the relationships between its reforms and education policy. Findings illustrate how the intermediary enacted…

  3. 46 CFR Appendix C to Subpart C of... - Ocean Transportation Intermediary (OTI) Guaranty Form [Form 68

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 9 2010-10-01 2010-10-01 false Ocean Transportation Intermediary (OTI) Guaranty Form C Appendix C to Subpart C of Part 515 Shipping FEDERAL MARITIME COMMISSION REGULATIONS AFFECTING OCEAN... Intermediaries Pt. 515, Subpart C, App. C Appendix C to Subpart C of Part 515—Ocean Transportation...

  4. Biochemist-Tree: Using Modular Origami to Understand the Integration of Intermediary Metabolism

    Science.gov (United States)

    Sharp, Duncan

    2013-01-01

    Intermediary metabolism can be a complex area to study due to the inherent modularity of the catabolic biochemical processes. This article outlines a novel, cost-effective, and universally applicable teaching activity to enhance students understanding of the inter-relationship between the key processes of intermediary metabolism. A simple origami…

  5. The Modern Cult of Efficiency: Intermediary Organizations and the New Scientific Management

    Science.gov (United States)

    Trujillo, Tina

    2014-01-01

    This article analyzes one intermediary organization. It draws on critical policy studies to frame the agency's behaviors amid a discourse of managerialism in the public sector, and critical studies of education markets to explain the relationships between its reforms and education policy. Findings illustrate how the intermediary enacted…

  6. Biochemist-Tree: Using Modular Origami to Understand the Integration of Intermediary Metabolism

    Science.gov (United States)

    Sharp, Duncan

    2013-01-01

    Intermediary metabolism can be a complex area to study due to the inherent modularity of the catabolic biochemical processes. This article outlines a novel, cost-effective, and universally applicable teaching activity to enhance students understanding of the inter-relationship between the key processes of intermediary metabolism. A simple origami…

  7. Topology of growing networks accelerated by intermediary process

    Science.gov (United States)

    Ikeda, Nobutoshi

    2017-10-01

    We examined the effect of accelerated growth (increase in the mean vertex degree) caused by internal links between pre-existing nodes on the topology of growing networks and showed that a kind of local rule, edge additions stimulated by randomly chosen intermediaries (intermediary process), not only guarantees a highly clustered structure but also induces the scale-free property on growing networks without an explicit preferential rule with the aid of accelerating growth. We relate the power-law exponent γ describing the degree distribution to the rate of acceleration and an internal factor which expresses the contribution of internal links to the rate of increase in degrees. The behavior of the internal factor generates different forms of time dependence of degrees according to whether γ > 2 or γ < 2. Accelerating growth plays a dominant role in the structural formation of networks based on local rules, in contrast to cases when non-local rules are applied, because similar studies showed that a simple preferential linking rule (a non-local rule) easily induces power laws without accelerating growth.

  8. A Novel Intermediary Framework for Dynamic Edge Service Composition

    Institute of Scientific and Technical Information of China (English)

    Claudia Canali; Michele Colajanni; Delfina Malandrino; Vittorio Scarano; Raffaele Spinelli

    2012-01-01

    Multimedia content,user mobility and heterogeneous client devices require novel systems that are able to support ubiquitous access to the Web resources.In this scenario,solutions that combine flexibility,efficiency and scalability in offering edge services for ubiquitous access are needed.We propose an original intermediary framework,namely Scalable Intermediary Software Infrastructure (SISI),which is able to dynamically compose edge services on the basis of user preferences and device characteristics.The SISI framework exploits a per-user profiling mechanism,where each user can initially set his/her personal preferences through a simple Web interface,and the system is then able to compose at run-time the necessary components.The basic framework can be enriched through new edge services that can be easily implemented through a programming model based on APIs and internal functions.Our experiments demonstrate that flexibility and edge service composition do not affect the system performance.We show that this framework is able to chain multiple edge services and to guarantee stable performance.

  9. Supply risk management functions of sourcing intermediaries – an investigation of the clothing industry

    DEFF Research Database (Denmark)

    Vedel, Mette; Ellegaard, Chris

    2013-01-01

    Purpose: The purpose of this research is to uncover how buying companies use sourcing intermediaries to manage supply risks in global sourcing. Design/methodology/approach: We carry out an explorative qualitative study of the clothing industry, interviewing key respondents that occupy different...... positions in the supply chain, including sourcing intermediaries, retailers, and brand marketers. Findings: Sourcing intermediaries carry out a broad range of supply risk management functions, including design availability and support, and the operation of high risk markets. We identify different sourcing...... by identifying the supply risk management functions that sourcing intermediaries carry out for buying companies. We also contribute by uncovering different types of sourcing intermediaries, determined by the collection of functions handled....

  10. The Road to C4 Photosynthesis: Evolution of a Complex Trait via Intermediary States.

    Science.gov (United States)

    Schlüter, Urte; Weber, Andreas P M

    2016-05-01

    C4 photosynthesis enables high photosynthetic energy conversion efficiency as well as high nitrogen and water use efficiencies. Given the multitude of biochemical, structural and molecular changes in comparison with C3 photosynthesis, it appears unlikely that such a complex trait would evolve in a single step. C4 photosynthesis is therefore believed to have evolved from the ancestral C3 state via intermediary stages. Consequently, the identification and detailed characterization of plant species representing transitory states between C3 and C4 is important for the reconstruction of the sequence of evolutionary events, especially since C4 evolution occurred in very different phylogenetic backgrounds. There is also significant interest in engineering of C4 or at least C4-like elements into C3 crop plants. A detailed and mechanistic understanding of C3-C4 intermediates is likely to provide guidance for the experimental design of such approaches. Here we provide an overview on the most relevant results obtained on C3-C4 intermediates to date. Recent knowledge gains in this field will be described in more detail. We thereby concentrate especially on biochemical and physiological work. Finally, we will provide a perspective and outlook on the continued importance of research on C3-C4 intermediates.

  11. Intermediary Cities in the territorial integration of Global South

    Directory of Open Access Journals (Sweden)

    Borja M. Iglesias

    2016-12-01

    Full Text Available “Economies of agglomeration” have acted as catalysts of the progress and modernisation of many nations in the Global South but have also contributed to unbalancing the territory, widening the gap between urban and rural populations and the accumulation of high environmental and social deficits. In contrast to the BRICS (Brazil, Russia, India, China and South Africa, the economies that make up the MINTs (Mexico, Indonesia, Nigeria and Turkey have better territorial integration of their urban systems, with intermediate cities that act as “economies of intermediation” with the rural hinterlands, and which could contribute to achieving the United Nations’ 2030 Agenda for Sustainable Development Goals. The United Nations Habitat iii of October 2016 placed intermediary cities at the heart of the New Urban Agenda. The aim is to promote national urban policies in many of the economies of the Global South, allowing them to strengthen their role as the main instrument of economic integration and regional cohesion.

  12. Intermediation in Foreign Trade: When do Exporters Rely on Intermediaries?

    DEFF Research Database (Denmark)

    Schröder, Philipp J.H.; Trabold, H.; Trübswetter, P.

    2005-01-01

    The paper explores the question of why trade intermediaries (TIs) are frequently used as agents for exports to some countries but not to others. First, we adapt a standard intra-industry trade model with variable export costs (e.g. transport) and fixed export costs (e.g. market access) to include...... a TI that is able to pool market access cost. This framework suggests explanatory factors for the TI share in a country's exports, which are largely in line with the literature. Second, we test these explanatory factors with a new data set based on French customs information. The paper finds that: (i......) higher market access costs increase the TI share, (ii) smaller export markets feature a larger TI share, (iii) network effects are important determinants of trade intermediation....

  13. Intermediation in Foreign Trade: When do Exporters Rely on Intermediaries?

    DEFF Research Database (Denmark)

    Schröder, Philipp; Trabold, Harald; Trübswetter, Parvati

    2003-01-01

    The paper explores theoretically and empirically why trade intermediaries (TIs) are frequently used as agents for exports to some countries but not to others. We adapt a standard intra-industry trade model with variable export costs (e.g. transport) and fixed export costs (e.g. market access......) to include a TI that is able to pool market access cost. From this framework explanatory factors for the TI share in a country's exports are derived and subsequently tested with a new data set based on French customs information. The paper finds that: (i) higher market access costs increase the TI share, (ii......) smaller export markets feature a larger TI share, (iii) the TI share is independent from variable (distance-dependent) export costs....

  14. The indispensable intermediaries: a qualitative study of informal caregivers' struggle to achieve influence at and after hospital discharge.

    Science.gov (United States)

    Bragstad, Line Kildal; Kirkevold, Marit; Foss, Christina

    2014-07-30

    The care policy and organization of the care sector is shifting to accommodate projected demographic changes and to ensure a sustainable model of health care provision in the future. Adult children and spouses are often the first to assume care giving responsibilities for older adults when declining function results in increased care needs. By introducing policies tailored to enabling family members to combine gainful employment with providing care for older relatives, the sustainability of the future care for older individuals in Norway is more explicitly placed on the family and informal caregivers than previously. Care recipients and informal caregivers are expected to take an active consumer role and participate in the care decision-making process. This paper aims to describe the informal caregivers' experiences of influencing decision-making at and after hospital discharge for home-bound older relatives. This paper reports findings from a follow-up study with an exploratory qualitative design. Qualitative telephone interviews were conducted with 19 informal caregivers of older individuals discharged from hospital in Norway. An inductive thematic content analysis was undertaken. Informal caregivers take on comprehensive all-consuming roles as intermediaries between the care recipient and the health care services. In essence, the informal caregivers take the role of the active participant on behalf of their older relative. They describe extensive efforts struggling to establish dialogues with the "gatekeepers" of the health care services. Achieving the goal of the best possible care for the care recipient seem to depend on the informal caregivers having the resources to choose appropriate strategies for gaining influence over decisions. The care recipients' extensive frailty and increasing dependence on their families coupled with the complexity of health care services contribute to the perception of the informal caregivers' indispensable role as intermediaries

  15. Exploring the role of intermediaries in firm-user community collaborations: resolving or multiplying conflicts?

    DEFF Research Database (Denmark)

    Dragsdahl Lauritzen, Ghita

    2015-01-01

    in which they originate. Nevertheless, despite its popularity there is still a paucity of studies on intermediaries mediating firm-community collaboration. On the basis of an embedded case study, this article suggests that instead of resolving conflicts, intermediaries create a new membership construct...... from which new tensions arise. I propose that if intermediary organizations foster a clearer view of this membership construct, the result can be an innovative synthesis of opposing logics. Thus, I suggest a novel approach to the debate about user innovation by arguing that mediating firm......-community collaboration is not a matter of bridging opposing logics, but of managing new forms of membership uncertainty...

  16. The Brazilian approach to internet intermediary liability: blueprint for a global regime?

    Directory of Open Access Journals (Sweden)

    Nicolo Zingales

    2015-12-01

    Full Text Available While intermediary liability is becoming an issue of increasing importance in internet governance discussions, little is being made at the institutional level to minimise conflicts across jurisdictions and ensure the compliance of intermediary liability laws with fundamental rights and the freedom to innovate. The experience leading to the adoption of the Brazilian “Marco Civil da Internet” offers concrete insights for the definition of a baseline framework at the international level. This article also suggests the creation of a global forum of discussion on intermediary liability, allowing the interests of a variety of stakeholders to be taken into account in the definition and implementation of those baseline principles.

  17. Controlling noise in plasmonic structures with gain

    Science.gov (United States)

    Vyshnevyy, A. A.; Fedyanin, D. Yu.

    2017-09-01

    Loss compensation by gain medium gives the possibility to exploit subwavelength confinement of light in plasmonic nanostructures and construct nanoscale plasmonic circuits. However, due to fundamentally unavoidable spontaneous emission from the gain medium, lossless waveguides suffer from strong photonic noise, which limits their practical applications. Here we demonstrate the possibility of significant decrease of the noise level while preserving physical dimensions of lossless plasmonic waveguides with gain. Our findings are aimed at extending the communication capabilities of on-chip plasmonic networks.

  18. Health and safety in small enterprises in Denmark and the role of intermediaries

    DEFF Research Database (Denmark)

    Hasle, Peter

    An analysis of the working environment for small enterprises in Denmark. Focussing especially on the working environment regulation and the role of intermediaries such as the occupational health service, the social partners and the labour inspectorate....

  19. 77 FR 76483 - Ocean Transportation Intermediary License Applicants The Commission gives notice that the...

    Science.gov (United States)

    2012-12-28

    ... Transportation Intermediary (OTI) license as a Non-Vessel-Operating Common Carrier (NVO) and/or Ocean Freight Forwarder (OFF) pursuant to section 19 of the Shipping Act of 1984 (46 U.S.C. 40101). Notice is also given...

  20. Demand articulation in emerging technologies: Intermediary user organisations as co-producers?

    NARCIS (Netherlands)

    Boon, Wouter P.C.; Moors, Ellen H.M.; Kuhlmann, Stefan; Smits, Ruud E.H.M.

    2010-01-01

    User involvement is assumed to be beneficial to innovation processes. Intermediary user organisations contribute to articulating societal demands for innovations. However, the learning processes inside these organisations are still not understood well. Therefore, this paper empirically investigates

  1. Demand articulation in emerging technologies: intermediary user organizations as co-producers?

    NARCIS (Netherlands)

    Boon, W.P.C.; Moors, E.H.M.; Kuhlmann, S.; Smits, R.E.H.M.

    2011-01-01

    User involvement is assumed to be beneficial to innovation processes. Intermediary user organisations contribute to articulating societal demands for innovations. However, the learning processes inside these organisations are still not understood well. Therefore, this paper empirically investigates

  2. An Intermediary Quaternion-based Control for Trajectory Following Using a Quadrotor

    OpenAIRE

    Colmenares-Vazquez, Jose; Marchand, Nicolas; Castillo Garcia, Pedro; Gomez-Balderas, Jose-Ernesto

    2017-01-01

    International audience; — This work uses the intermediary quaternions in the design of a backstepping control technique with integral properties in order to perform an autonomous trajectory tracking using a quadcopter vehicle. Nowadays, in order to determine the orientation of a vehicle, most of the inertial systems of aircrafts can give directly the rotation matrix and taking advantage of this fact, the intermediary quaternions can be determined in a simple way from this matrix. Moreover, on...

  3. LEO intermediary propagation as a feasible alternative to Brouwer's gravity solution

    OpenAIRE

    Lara, Martin

    2014-01-01

    The performance of Brouwer's gravity solution is compared with Deprit's second-order radial intermediary. Taking the main problem of the artificial satellite as the test model, that is perturbations are limited to the effects of the second zonal harmonic, it is demonstrated that the intermediary solution provides an efficient alternative for the analytical propagation of low earth orbits in a range determined by non-impact orbits with eccentricities below one tenth.

  4. LEO intermediary propagation as a feasible alternative to Brouwer's gravity solution

    Science.gov (United States)

    Lara, Martin

    2015-08-01

    The performance of Brouwer's gravity solution is compared with Deprit's second-order radial intermediary. Taking the main problem of the artificial satellite as the test model, that is perturbations are limited to the effects of the second zonal harmonic, it is demonstrated that the intermediary solution provides an efficient alternative for the analytical propagation of low earth orbits in a range determined by non-impact orbits with eccentricities below one tenth.

  5. Health and safety in small enterprises in Denmark and the role of intermediaries

    DEFF Research Database (Denmark)

    Hasle, Peter

    An analysis of the working environment for small enterprises in Denmark. Focussing especially on the working environment regulation and the role of intermediaries such as the occupational health service, the social partners and the labour inspectorate.......An analysis of the working environment for small enterprises in Denmark. Focussing especially on the working environment regulation and the role of intermediaries such as the occupational health service, the social partners and the labour inspectorate....

  6. The Brazilian Approach to Internet Intermediary Liability: Blueprint for a Global Regime?

    OpenAIRE

    Nicolo Zingales

    2014-01-01

    While intermediary liability is becoming an issue of increasing importance in internet governance discussions, little is being made at the institutional level to minimise conflicts across jurisdictions and ensure the compliance of intermediary liability laws with fundamental rights and the freedom to innovate. The experience leading to the adoption of the Brazilian “Marco Civil da Internet” offers concrete insights for the definition of a baseline framework at the international level. This ar...

  7. Intermediaries as Innovating Actors in the Transition to a Sustainable Energy System

    Directory of Open Access Journals (Sweden)

    Julia Backhaus

    2010-07-01

    Full Text Available In transitions of large sociotechnical systems, intermediary organisations can emerge as mediators in between several actor groups and facilitate communication and collaboration towards common goals. They can support the establishment of new actor networks and the articulation and alignment of interests to bring about desired changes. In this article, current efforts towards a more sustainable energy system serve as an exemplary context of intermediary work. The field under scrutiny, demand side management, aims to decrease energy consumption. Unfortunately, the role and work of intermediaries as implementers of demand side management projects often remains underappreciated.
    Research into the reasons of successes and failures of intermediary work and a theoretical corroboration for their practical work can help intermediaries to improve their programme designs and implementation strategies. The EC FP7-funded Changing Behaviour project aims to support intermediaries with strategic activities to improve demand side management programmes and bring about lasting behavioural changes. Paying more attention to context, stakeholders, monitoring, evaluation and learning enables the development of tailor-made, widely supported projects with higher chances of success.
    In addition to practical support for their work, intermediaries can benefit from stronger policy support. Understanding and appreciation of their work as contribution to policy implementation, e.g. towards energy saving targets, could motivate such support. A stable policy and financial environment with long-term implementation plans and funding schemes provides a fertile ground for intermediary activities. Active participation of policy actors in demand side management programmes can create networks sustaining longer-lasting change.

  8. Small and Medium Enterprises using Software as a Service: Exploring the different roles of intermediaries

    Directory of Open Access Journals (Sweden)

    Nagarajan Venkatachalam

    2014-11-01

    Full Text Available Software as a Service (SaaS can provide significant benefits to small and medium enterprises (SMEs due to advantages like ease of access, 7*24 availability, and utility pricing. However, underlying the SaaS delivery model is often the assumption that SMEs will directly interact with the SaaS vendor and use a self-service approach. In practice, we see the rise of SaaS intermediaries who can support SMEs with sourcing and leveraging SaaS. This paper reports on the roles of intermediaries and how they support SMEs with using SaaS. We conducted an empirical study of two SaaS intermediaries and analysed their business models, in particular their value propositions. We identified orientation (technology or customer and alignment (operational or strategic as themes for understanding their roles. The contributions of this paper include: (1 the identification and description of SaaS intermediaries for SMEs based on an empirical study and (2 understanding the different roles of SaaS intermediaries, in particular a more basic role based on technology orientation and operational alignment and a more value adding role based on customer orientation and strategic alignment. We propose that SaaS intermediaries can address SaaS adoption and implementation challenges of SMEs by playing a basic role and can also aim to support SMEs in creating business value with SaaS based solutions by playing an added value role.

  9. Inborn Errors of Intermediary Metabolism in Critically Ill Mexican Newborns

    Directory of Open Access Journals (Sweden)

    Ibarra-González Isabel MSc

    2014-04-01

    Full Text Available Inborn errors of intermediary metabolism (IEiM are complex diseases with high clinical heterogeneity, and some patients who have severe enzyme deficiencies or are subjected to stress (catabolism/infections actually decompensate in the neonatal period. In this study, we performed metabolic tests on 2025 newborns in Mexico admitted to 35 neonatal intensive care units or emergency wards (NICUs/EWs over a 6-year period, in whom a metabolic disorder was clinically suspected. Of these 2025 newborns with sickness, 11 had IEiM, revealing a prevalence of 1:184. Clinical characteristics and outcomes of the newborns with confirmed IEiM are shown. Of these 11 patients, 4 had isolated methylmalonic acidemia, 3 had maple syrup urine disease, 2 had urea cycle disorders, 1 had 3-hydroxy-3-methylglutaric acidemia, and 1 had isovaleric acidemia. During the first week of life (average 3 days, all of these newborns presented with impaired alertness, hypotonia, feeding difficulties, and vomiting along with metabolic acidosis and hyperammonemia. Of the 11 newborns with IEiM, 7 died, leading to a mortality rate of 64%. In conclusion, the differential diagnosis of newborns admitted to the NICU/EW must include IEiM, requiring systematic screening of this population.

  10. Enhanced Gain in Photonic Crystal Amplifiers

    DEFF Research Database (Denmark)

    Ek, Sara; Semenova, Elizaveta; Hansen, Per Lunnemann;

    2012-01-01

    study of a 1 QW photonic crystal amplifier. Net gain is achieved which enables laser oscillation in photonic crystal micro cavities. The ability to freely tailor the dispersion in a semiconductor optical amplifier makes it possible to raise the optical gain considerably over a certain bandwidth......We experimentally demonstrate enhanced gain in the slow-light regime of quantum well photonic crystal amplifiers. A strong gain enhancement is observed with the increase of the group refractive index, due to light slow-down. The slow light enhancement is shown in a amplified spontaneous emission...

  11. Implementing best practice in infection prevention and control. A realist evaluation of the role of intermediaries.

    Science.gov (United States)

    Williams, Lynne; Rycroft-Malone, Jo; Burton, Christopher R

    2016-08-01

    Implementing best practice in healthcare is complex. There is evidence to suggest that certain individuals, collectively termed 'intermediaries', can contribute to implementation processes, but understanding exactly what happens and how intermediaries promote best practice is unclear. The aim of this study was to evaluate the role of intermediaries in promoting infection prevention, and provide an explanation about what works, for whom, how, and under which conditions. Realist methodology was used as the underpinning explanatory framework for the study. From a concept mining of the existing literature, a set of hypothetical statements about the plausible range of context-mechanism-outcome propositions that postulate how intermediaries can contribute to promoting best practice were developed and evaluated. Case studies were conducted consecutively to refine and test the propositions. Data included semi-structured interviews (n=32), non-participant observations (n=5) and documentation review. Data were analysed by open coding, content and pattern matching. Case studies were undertaken in two hospitals within the United Kingdom. Purposive sampling was used to identify individuals within the organisations who had professional or organisational responsibilities for infection prevention. The inclusion criteria were; employees of the chosen organisations who would consent to take part in the study, participants with infection prevention responsibilities, adults over 18 years with the capacity to consent. The exclusion criteria were; participants outside of the chosen organisation, participants under 18 years of age, and participants who lacked the capacity to consent. Four context-mechanism-outcome configurations contribute to advancing our understanding about the potential of intermediaries to promote best practice. Findings showed that the ways in which intermediaries watch over practice (their human surveillance), promoted better adherence with infection control

  12. Asthma Triggers: Gain Control

    Science.gov (United States)

    ... Search Asthma Contact Us Share Asthma Triggers: Gain Control Breathing Freely: Controlling Asthma Triggers This video features ... Air Quality: Biological Pollutants Help Your Child Gain Control Over Asthma Top of Page Molds About Molds ...

  13. Deliverable 7. Conceptualizing and understanding intermediaries in context. Developing an enhanced understanding of context, actors and transferability

    Energy Technology Data Exchange (ETDEWEB)

    Mourik, R.M.; Feenstra, C.F.J.; Breukers, S. [ECN Policy Studies, Petten (Netherlands); Heiskanen, E.; Rask, M.; Saastamoinen, M.; Korhonen, L. [National Consumer Research Centre NCRC, Helsinki (Finland); Barabanova, Y.; Pariag, J. [Central European University CEU, Budapest (Hungary); Bauknecht, D.; Brohmann, B.; Buerger, V. [Institute for Applied Ecology OEKO, Freiburg (Germany); Hodson, M.; Marvin, S. [The SURF Centre, University of Salford, Manchester (United Kingdom); Jalas, M.; Rinne, S.; Salminnen, J. [Enespa Ltd. (Finland); Maier, P.; Meinel, H. [Verbraucherzentrale Nordrhein-Westfalen e.V. VZ NRW, Duesseldorf (Germany); Robinson, S. [Manchester Knowledge Capital MKC, Manchester Enterprises ME, Manchester (United Kingdom); Valuntiene, I. [Cowi Baltic, Vilnius (Lithuania); Vadovics, E. [GreenDependent Sustainable Solutions Association, Magyarorszag (Hungary)

    2009-10-15

    Changing Behaviour is a project that aims to support change in energy use and energy services by applying social research on technological change to practical use. The focus is on the interaction between energy experts and energy users: How can these different groups learn to understand each other better. D7 identifies intermediary practices in Europe. The identification of intermediary practices is important as it is 'energy intermediaries' that mediate between policy priorities and end-user practices. This report conceptualises the different roles and the strategic capabilities needed by energy intermediaries. Through an analysis of 25 European case studies the report 'gets inside' energy intermediary practice to improve our understanding of who intermediaries are, how they function, what problems the encounter. and how they can do better.

  14. 13 CFR 120.702 - Are there limitations on who can be an Intermediary or on where an Intermediary may operate?

    Science.gov (United States)

    2010-01-01

    ... requirement. To be eligible to be an Intermediary, an organization must: (1) Have made and serviced short-term fixed rate loans of not more than $35,000 to newly established or growing small businesses for at least... would be in the best interests of the small business community for it to operate across state lines. ...

  15. The Role of Travel Intermediaries in the Development of Sustainable Mountain Tourism - the Case of Turkey

    Directory of Open Access Journals (Sweden)

    Icoz Onur

    2012-04-01

    Full Text Available The aim of the study is to investigate the current situation of mountain tourism and its sustainability in Turkey. Not only the tourism policies of the government are enough to promote a new alternative tourism type, but also the role and effects of tourism middlemen such as travel agencies, tour operators, and tour wholesalers cannot be denied in the promotion of a destination. Mountain tourism could be one of the best alternative tourism opportunities for many destinations if they have sufficient resources, namely naturally attractive mountains and related infra and/or superstructure. Turkey and Aegean region have many attractive resources in this sense. In this research, in addition to analyzing the current situation in Turkey; ways of developing mountain tourism in a sustainable way as well as possible roles and effects of travel intermediaries in this area are questioned. With this purpose, the contents of the research vary differently. The first part depends on literature review presenting general definitions and discussions concerning mountain tourism. In the second part of the study, tourism policies in general and the mountain tourism policies of Turkish Government will be discussed. In the last part, the field survey is applied by developing and distributing questionnaire to major group A travel agencies in Turkey and outbound tour operators organizing tours to Turkey as well. The sample of the research consists of 83 firms and each was reached via e-mail. The data gained through the survey were analysed by computer based statistical program, SPSS 16. In the discussion part of the research, depending on the major findings, the comments and suggestions for further researches were developed.

  16. FEL gain optimisation and spontaneous radiation

    Energy Technology Data Exchange (ETDEWEB)

    Bali, L.M.; Srivastava, A.; Pandya, T.P. [Lucknow Univ. (India)] [and others

    1995-12-31

    Colson have evaluated FEL gains for small deviations from perfect electron beam injection, with radiation of the same polarisation as that of the wiggler fields. We find that for optimum gain the polarisation of the optical field should be the same as that of the spontaneous emission under these conditions. With a helical wiggler the axial oscillations resulting from small departures from perfect electron beam injection lead to injection dependent unequal amplitudes and phases of the spontaneous radiation in the two transverse directions. Viewed along the axis therefore the spontaneous emission is elliptically polarised. The azimuth of the ellipse varies with the difference of phase of the two transverse components of spontaneous emission but the eccentricity remains the same. With planar wigglers the spontaneous emission viewed in the axial direction is linearly polarised, again with an injection dependent azimuth. For optimum coherent gain of a radiation field its polarisation characteristics must be the same as those of the spontaneous radiation with both types of wiggler. Thus, with a helical wiggler and the data reported earlier, an increase of 10% in the FEL gain at the fundamental frequency and of 11% at the fifth harmonic has been calculated in the small gain per pass limit. Larger enhancements in gain may result from more favourable values of input parameters.

  17. Marriage formation as a process intermediary between migration and childbearing

    Directory of Open Access Journals (Sweden)

    Lesia Nedoluzhko

    2008-06-01

    Full Text Available In studies of differences in fertility between migrants and non-migrants, marriage interferes because migration can be motivated by an impending marriage or can entail entry into a marriage market with new opportunities. One would therefore expect elevated fertility after migration, although a competing theory states that on the contrary fertility ought to be reduced in the time around the move because migration temporarily disturbs the life of the migrant. In any case marriage appears as a process that is intermediary between migration and childbearing. To handle such issues it pays to have a technique that allows the analyst to separate any disruptive effects of migration from any boosting effects of marriage in studies of childbearing. The purposes of the present paper are (i to remind us that such a technique is available, in fact is straightforward, and (ii to apply the technique to further analyze a set of data on migration and first-time parenthood in Kyrgyzstan recently used by the second author and Gunnar Andersson. The technique has the neat feature that it allows us to operate with several "clocks" at the same time. In the analysis of first births we keep track of time since migration (for migrants and time since marriage formation (for the married beside the respondent's age (for women at childbearing ages; in other connections there may be more clocks. For such analyses we make use of a flexible graphical housekeeping device that allows the analyst to keep track of a feature like whether migration occurs before or after marriage, or at the same time. This is a half-century-old flow chart of statuses and transitions and is not much more complex than the famous Lexis diagram, which originated with Gustav Zeuner, as we now know. These reflexions were first presented at a symposium dedicated to Professor Zeuner.

  18. Regulation of intermediary metabolism by the PKCδ signalosome in mitochondria

    Science.gov (United States)

    Acin-Perez, Rebeca; Hoyos, Beatrice; Gong, Jianli; Vinogradov, Valerie; Fischman, Donald A.; Leitges, Michael; Borhan, Babak; Starkov, Anatoly; Manfredi, Giovanni; Hammerling, Ulrich

    2010-01-01

    PKCδ has emerged as a novel regulatory molecule of oxidative phosphorylation by targeting the pyruvate dehydrogenase complex (PDHC). We showed that activation of PKCδ leads to the dephosphorylation of pyruvate dehydrogenase kinase 2 (PDK2), thereby decreasing PDK2 activity and increasing PDH activity, accelerating oxygen consumption, and augmenting ATP synthesis. However, the molecular components that mediate PKCδ signaling in mitochondria have remained elusive so far. Here, we identify for the first time a functional complex, which includes cytochrome c as the upstream driver of PKCδ, and uses the adapter protein p66Shc as a platform with vitamin A (retinol) as a fourth partner. All four components are necessary for the activation of the PKCδ signal chain. Genetic ablation of any one of the three proteins, or retinol depletion, silences signaling. Furthermore, mutations that disrupt the interaction of cytochrome c with p66Shc, of p66Shc with PKCδ, or the deletion of the retinol-binding pocket on PKCδ, attenuate signaling. In cytochrome c-deficient cells, reintroduction of cytochrome c Fe3+ protein restores PKCδ signaling. Taken together, these results indicate that oxidation of PKCδ is key to the activation of the pathway. The PKCδ/p66Shc/cytochrome c signalosome might have evolved to effect site-directed oxidation of zinc-finger structures of PKCδ, which harbor the activation centers and the vitamin A binding sites. Our findings define the molecular mechanisms underlying the signaling function of PKCδ in mitochondria.—Acin-Perez, R., Hoyos, B., Gong, J., Vinogradov, V., Fischman, D. A., Leitges, M., Borhan, B., Starkov, A., Manfredi, G., Hammerling, U. Regulation of intermediary metabolism by the PKCδ signalosome in mitochondria. PMID:20798245

  19. Correlates of the intention to implement a tailored physical activity intervention: perceptions of intermediaries.

    Science.gov (United States)

    Peels, Denise; Mudde, Aart; Bolman, Catherine; Golsteijn, Rianne; de Vries, Hein; Lechner, Lilian

    2014-02-10

    The public health impact of health behaviour interventions is highly dependent on large-scale implementation. Intermediaries-intervention providers-determine to a large extent whether an intervention reaches the target population, and hence its impact on public health. A cross-sectional study was performed to identify the correlates of intermediaries' intention to implement a computer-tailored physical activity intervention. According to theory, potential correlates are intervention characteristics, organisational characteristics, socio-political characteristics and intermediary characteristics. This study investigated whether intermediary characteristics mediated the association between the intervention, organisational and socio-political characteristics and intention to implement the intervention. Results showed that intervention characteristics (i.e., observability (B = 0.53; p = 0.006); relative advantage (B = 0.79; p = 0.020); complexity (B = 0.80; p organisational characteristics (i.e., type of organization (B = 0.38; p = 0.002); perceived task responsibility (B = 0.66; p ≤ 0.001); capacity (B = 0.83; p organisations (B = 0.81; p strategy. Since self-efficacy and social norms perceived by the intermediary organisations partially mediated the effects of other variables on intention to implement the intervention (varying between 29% and 84%), these factors should be targeted to optimise the effectiveness of the implementation strategy.

  20. Analysis Of The Logistics Intermediaries Choice Methods In The Supply Chains

    Directory of Open Access Journals (Sweden)

    Lukinskiy Valery

    2015-12-01

    Full Text Available The increase of the supply chains efficiency requires optimization of all types of logistic operations and functions. One of such functions is the choice of intermediaries (carriers, freight forwarders, suppliers, service enterprises etc. and, according to some specialists, it is a major strategic decision in management supply chains. The methods of choosing the logistic intermediaries are considered in many works, however, some questions remain debatable. The article discusses the analytical and expert approaches which serve as a basis to choose the intermediaries; along with it, in the article a comparative evaluation of choice expert methods is done: point-rating assessment, analytic hierarchy process and the general algorithm for selecting; the conclusions have been drawn about the applicability of each method.

  1. Digital automatic gain control

    Science.gov (United States)

    Uzdy, Z.

    1980-01-01

    Performance analysis, used to evaluated fitness of several circuits to digital automatic gain control (AGC), indicates that digital integrator employing coherent amplitude detector (CAD) is best device suited for application. Circuit reduces gain error to half that of conventional analog AGC while making it possible to automatically modify response of receiver to match incoming signal conditions.

  2. Exploration into Stages in the Information Search Process in Online Information Retrieval: Communication between Users and Intermediaries.

    Science.gov (United States)

    Kuhlthau, Carol; And Others

    1992-01-01

    Describes a study that examined interactions between users and intermediaries prior to online searching to examine communication about the user's stage in the search process. A model of information seeking that views the information search process as a series of cognitive stages is presented, and implications for user-intermediary interactions are…

  3. Emergence of Financial Intermediaries in Electronic Markets: The Case of Online P2P Lending

    Directory of Open Access Journals (Sweden)

    Sven C. Berger

    2009-05-01

    Full Text Available We analyze the role of intermediaries in electronic markets using detailed data of more than 14,000 originated loans on an electronic P2P (peer-to-peer lending platform. In such an electronic credit market, lenders bid to supply a private loan. Screening of potential borrowers and the monitoring of loan repayment can be delegated to designated group leaders. We find that these market participants act as financial intermediaries and significantly improve borrowers' credit conditions by reducing information asymmetries, predominantly for borrowers with less attractive risk characteristics. Our findings may be surprising given the replacement of a bank by an electronic marketplace.

  4. Organising the unorganised: Role of platform intermediaries in the Indian real estate market

    Directory of Open Access Journals (Sweden)

    R. Srinivasan

    2017-03-01

    Full Text Available A large component of the Indian economy is still in the unorganised (or informal sector. The emergence of new intermediaries leveraging the Internet has contributed significantly to organising the hitherto unorganised sector. We discuss the case of the Indian real estate industry and elucidate how Internet-based intermediaries have mitigated the problems associated with the unorganised nature of the industry. The three primary problems associated with the unorganised nature of the industry are adverse selection, moral hazard, and weak contract enforcement. Leaders representing four leading real estate platforms discuss how organising the real estate business as a platform business model helps mitigate these risks.

  5. Exploring the role of intermediary organizations in firm and user community collaborations: Resolving or multiplying paradoxes?

    DEFF Research Database (Denmark)

    Dragsdahl Lauritzen, Ghita

    2015-01-01

    Research on user innovation shows that innovation can be impeded by the conflicting demands that arise in the context of collaborations between firms and their user communities. One stream of research, however, applies a paradox lens to argue that intermediary organizations can help to resolve...... these conflicts, by bridging the opposing logics in which they originate. On the basis of an embedded case study, this article suggests that instead of resolving a paradox of innovation, intermediaries create new paradoxical tensions. Further, I argue that mediating firm-community collaboration is not a matter...

  6. PROBLEMS AND PROSPECTS OF INTERMEDIARY METABOLISM CORRECTION IN PATIENTS WITH VASCULAR COMORBIDITY

    Directory of Open Access Journals (Sweden)

    S. A. Rumyantseva

    2015-09-01

    Full Text Available Disorders of intermediary metabolism in the glycolysis cycles and fatty acids oxidation play a major role in heart and brain lesions of vascular origin. Features of the free-radical processes in various forms of vascular disease are presented. Differences within the free-radical processes reflecting the severity of tissue energy deficit are shown in stroke patients with concomitant ischemic heart disease, atrial fibrillation, and diabetes mellitus. Various aspects of the treatment of patients with vascular comorbidity are presented with the focus on correction of intermediary metabolism disorders. Complex energy correcting therapy including beta-oxidation blocker (meldonium is discussed.

  7. Do Research Intermediaries Reduce Perceived Coercion to Enter Research Trials Among Criminally Involved Substance Abusers?

    Science.gov (United States)

    Festinger, David S; Dugosh, Karen L; Croft, Jason R; Arabia, Patricia L; Marlowe, Douglas B

    2011-01-01

    We examined the efficacy of including a research intermediary (RI) during the consent process in reducing participants' perceptions of coercion to enroll in a research study. Eighty-four drug court clients being recruited into an ongoing study were randomized to receive a standard informed consent process alone (standard condition) or with an RI (intermediary condition). Before obtaining consent, RIs met with clients individually to discuss remaining concerns. Findings provided preliminary evidence that RIs reduced client perceptions that their participation might influence how clinical and judicial staff view them. This suggests that using RIs may improve participant autonomy in clinical studies.

  8. Comparing gains and losses.

    Science.gov (United States)

    McGraw, A Peter; Larsen, Jeff T; Kahneman, Daniel; Schkade, David

    2010-10-01

    Loss aversion in choice is commonly assumed to arise from the anticipation that losses have a greater effect on feelings than gains, but evidence for this assumption in research on judged feelings is mixed. We argue that loss aversion is present in judged feelings when people compare gains and losses and assess them on a common scale. But many situations in which people judge and express their feelings lack these features. When judging their feelings about an outcome, people naturally consider a context of similar outcomes for comparison (e.g., they consider losses against other losses). This process permits gains and losses to be normed separately and produces psychological scale units that may not be the same in size or meaning for gains and losses. Our experiments show loss aversion in judged feelings for tasks that encourage gain-loss comparisons, but not tasks that discourage them, particularly those using bipolar scales.

  9. Indoor acoustic gain design

    Science.gov (United States)

    Concha-Abarca, Justo Andres

    2002-11-01

    The design of sound reinforcement systems includes many variables and usually some of these variables are discussed. There are criteria to optimize the performance of the sound reinforcement systems under indoor conditions. The equivalent acoustic distance, the necessary acoustic gain, and the potential acoustic gain are parameters which must be adjusted with respect to the loudspeaker array, electric power and directionality of loudspeakers, the room acoustics conditions, the distance and distribution of the audience, and the type of the original sources. The design and installation of front of the house and monitoring systems have individual criteria. This article is about this criteria and it proposes general considerations for the indoor acoustic gain design.

  10. Weight gain - unintentional

    Science.gov (United States)

    ... be due to menstruation, heart or kidney failure, preeclampsia, or medicines you take. A rapid weight gain ... al. Position of the American Dietetic Association: weight management. J Am Diet Assoc . 2009;109:330-46. ...

  11. Metamaterials with Gain

    Science.gov (United States)

    Hess, Ortwin

    2012-02-01

    Nanoplasmonic metamaterials are the key to an extreme control of light and allow us to conceive materials with negative or vanishing refractive index. Indeed, metamaterials enable a multitude of exciting and useful applications, such as subwavelength focusing, invisibility cloaking, and ``trapped rainbow'' stopping of light. The realization of these materials has recently advanced from the microwave to the optical regime. However, at optical wavelengths, metamaterials may suffer from high dissipative losses owing to the metallic nature of their constituent nanoplasmonic meta-molecules. It is therefore not surprising that overcoming loss restrictions by gain is currently one of the most important topics in metamaterials' research. At the same time, providing gain on the nanoplasmonic (metamolecular) level opens up exciting new possibilities such as a whole new type of metamaterial nano-laser with a cavity length of about a tenth of the wavelength. The talk gives an overview of the state of the art of gain-enhanced metamaterials. Particular focus will be placed on nano-plasmonic metamaterials (such as double-fishnet metamaterials) with integrated laser dyes as gain medium. The successful compensation of loss by gain is demonstrated on the meta-molecular level. On the basis of a comprehensive, microscopic Maxwell-Bloch Langevin approach of spatio-temporal light amplification and lasing in gain-enhanced nanoplasmonic (negative-index) metamaterials a methodology based on the discrete Poynting's theorem is introduced that allows dynamic tracing of the flow of electromagnetic energy into and out of ``microscopic'' channels (light field, plasmons, gain medium). It is shown that steady-state amplification can be achieved in nanoplasmonic metamaterials. Finally, a complex spatio-temporal interplay of light-field and coherent absorption dynamics is revealed in the lasing dynamics of a nanoplasmonic gain-enhanced double-fishnet metamaterial.

  12. Transport Integration at European Ports: Measuring the Role and Position of Intermediaries

    NARCIS (Netherlands)

    Ducruet, C.; Van der Horst, M.R.J.

    2009-01-01

    The integration of ports within logistics and supply chains has become a major issue for both public and private players worldwide. Notably, the role of intermediaries in establishing efficient integration within transport chains in which ports are embedded is not well-known. International compariso

  13. Intermediary object for participative design processes based on the ergonomic work analysis

    DEFF Research Database (Denmark)

    Souza da Conceição, Carolina; Duarte, F.; Broberg, Ole

    2012-01-01

    The objective of this paper is to present and discuss the use of an intermediary object, built from the ergonomic work analysis, in a participative design process. The object was a zoning pattern, developed as a visual representation ‘mapping’ of the interrelations among the functional units of t...

  14. 26 CFR 1.643(h)-1 - Distributions by certain foreign trusts through intermediaries.

    Science.gov (United States)

    2010-04-01

    ... intermediaries. 1.643(h)-1 Section 1.643(h)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Estates, Trusts, and Beneficiaries § 1.643(h)-1... section, FT is deemed to have distributed XYZ stock with a value of 85X to C on December 1, 2001. (h...

  15. Superintendent-Business Executive Collaboration in Intermediary Organizations: Moral Agency and Democratic Functioning

    Science.gov (United States)

    Bennett, Jeffrey V.; McKee, Tiffany; Martin, Staci

    2014-01-01

    This case study describes collaboration between business executives and superintendents to influence local/regional K-12 educational change. Specifically, we examine participant like-mindedness about the ethics and appropriate focus of K-12 intermediary collaboration, the extent of democratic functioning, and key individuals to involve. Data…

  16. 75 FR 55409 - Regulation of Off-Exchange Retail Foreign Exchange Transactions and Intermediaries

    Science.gov (United States)

    2010-09-10

    ... trade forex, intermediaries, registered FCMs currently serving as counterparties in retail forex transactions, trade associations or coalitions of industry participants, one committee of a county lawyers... percentage of non-discretionary accounts that were profitable, to include the results of this calculation for...

  17. 42 CFR 476.80 - Coordination with Medicare fiscal intermediaries and carriers.

    Science.gov (United States)

    2010-10-01

    ... prospective payment system for health care services and items; (2) Exchanging data or information; (3... 42 Public Health 4 2010-10-01 2010-10-01 false Coordination with Medicare fiscal intermediaries and carriers. 476.80 Section 476.80 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES,...

  18. Labour Market Intermediaries: A Corrective to the Human Capital Paradigm (Mis)matching Skills and Jobs?

    Science.gov (United States)

    Dobbins, Tony; Plows, Alexandra

    2017-01-01

    The orthodox supply-side human capital theory (HCT) paradigm is inadequate for understanding and adjusting to labour market volatility in UK regional economies like Wales. This article explores the role of regional labour market intermediaries (LMIs) in matching supply (skills) and demand (job opportunities) in regional labour markets. Some LMIs…

  19. 77 FR 22576 - Possible Revocation of Ocean Transportation Intermediary License No. 021899-Trans World Logistics...

    Science.gov (United States)

    2012-04-16

    ... Possible Revocation of Ocean Transportation Intermediary License No. 021899--Trans World Logistics Corporation; Order To Show Cause Trans World Logistics Corporation (Trans World Logistics) is an Indiana... Licensing (BCL) indicate that Trans World Logistics maintains its principal offices at 702 Penny Lane...

  20. Superintendent-Business Executive Collaboration in Intermediary Organizations: Moral Agency and Democratic Functioning

    Science.gov (United States)

    Bennett, Jeffrey V.; McKee, Tiffany; Martin, Staci

    2014-01-01

    This case study describes collaboration between business executives and superintendents to influence local/regional K-12 educational change. Specifically, we examine participant like-mindedness about the ethics and appropriate focus of K-12 intermediary collaboration, the extent of democratic functioning, and key individuals to involve. Data…

  1. Transport Integration at European Ports: Measuring the Role and Position of Intermediaries

    NARCIS (Netherlands)

    Ducruet, C.; Van der Horst, M.R.J.

    2009-01-01

    The integration of ports within logistics and supply chains has become a major issue for both public and private players worldwide. Notably, the role of intermediaries in establishing efficient integration within transport chains in which ports are embedded is not well-known. International

  2. 13 CFR 120.1010 - SBA access to SBA Lender, Intermediary, and NTAP files.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false SBA access to SBA Lender, Intermediary, and NTAP files. 120.1010 Section 120.1010 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION BUSINESS LOANS Risk-Based Lender Oversight Supervision § 120.1010 SBA access to SBA...

  3. A New Direction for Technology-Based Economic Development: The Role of Innovation Intermediaries

    Science.gov (United States)

    Bendis, Richard A.; Seline, Richard S.; Byler, Ethan J.

    2008-01-01

    Accelerating innovation to drive economic growth is the foremost goal for technology-based economic development organizations today. Realizing this goal through programmes is challenged by limited and outdated operating models. The authors outline their 21st Century Innovation Intermediary model, which pairs commercialization with regional…

  4. Zooming in on regulatory intermediaries: The impact of non-state regulators on sustainable construction practice

    NARCIS (Netherlands)

    van der Heijden, J.

    2014-01-01

    Levi-Faur and Starobin (2013) have recently drawn our attention to the important role of regulatory intermediates in contemporary regulatory regimes. Among others they argue that regulatory intermediaries come in a wide variety of appearances, and that these can influence the outcomes of regulatory

  5. Welcome to the Jungle: the Liability of Internet Intermediaries for Privacy Violations in Europe

    NARCIS (Netherlands)

    B. van der Sloot

    2015-01-01

    In Europe, roughly three regimes apply to the liability of Internet intermediaries for privacy violations conducted by users through their network. These are: the e-Commerce Directive, which, under certain conditions, excludes them from liability; the Data Protection Directive, which imposes a numbe

  6. An impact of intermediaries' behaviour on customer satisfaction in an Indian Private Sector Bank

    Directory of Open Access Journals (Sweden)

    Dr.R.Amudha

    2014-01-01

    Full Text Available The consumer satisfaction towards the services provided by any organization will depend mainly upon the extent of communication with the customers. To be effective in terms of communication, a company must train its own intermediaries to behave in a manner in which the consumers want to behave. Positive staff attitude, sincerity, integrity, and reliability, sensible advice, delivery of promise, reliable delivery of superior quality service, simplicity and ease of doing business, superior after-sales service, reasonable and competent complaints handling policy on the part of the intermediaries are the determinants of customer loyalty. In India, the private sector banks are highly depending on the agencies outside their organization for the enhancement of their business. This is so because; they have found the investment to be cheaper to appoint the franchisees rather than to open their own branches. Private banks need to sell and cross-sell their products though doorstep banking which is achieved by a widespread direct sales force. The compensation of sales personnel depends on the volumes of business they fetch for the bank. To assess the behaviour of intermediaries of ICICI Bank, a survey is conducted with a sample size of 473 customers by administering an interview schedule. The data collected has been analysed with ANOVA single factor to study the impact of intermediaries’ behaviour on customer satisfaction and Weighted ANOVA to know the preference of the customers. The results show that, though ICICI Bank is viewed as an immediate service provider, the customers’ rate the service of the bank based on the attitude and behaviour of the intermediaries. This study is applicable to all service sectors like insurance, tourism, hospitality and computer education institutions operating with the marketing intermediaries.

  7. Relational Information Gain

    DEFF Research Database (Denmark)

    Lippi, Marco; Jaeger, Manfred; Frasconi, Paolo

    2011-01-01

    We introduce relational information gain, a refinement scoring function measuring the informativeness of newly introduced variables. The gain can be interpreted as a conditional entropy in a well-defined sense and can be efficiently approximately computed. In conjunction with simple greedy general......-to-specific search algorithms such as FOIL, it yields an efficient and competitive algorithm in terms of predictive accuracy and compactness of the learned theory. In conjunction with the decision tree learner TILDE, it offers a beneficial alternative to lookahead, achieving similar performance while significantly...

  8. Should I Gain Weight?

    Science.gov (United States)

    ... If you're having trouble with your body image, talk about how you feel with someone you like and trust who's been through it — maybe a parent, doctor, counselor, coach, or teacher. continue It's the Growth, Not the Gain No ...

  9. 1300-nm gain obtained with dysprosium-doped chloride crystals

    Energy Technology Data Exchange (ETDEWEB)

    Page, R.H.; Schaffers, K.I.; Beach, R.J.; Payne, S.A.; Krupke, W.F.

    1996-03-01

    Dy{sup 3+} - doped chloride crystals have high 1300-nm emission quantum yields. Pump - probe experiments on La Cl{sub 3}:Dy{sup 3+} demonstrate optical gain consistent with predictions based on spectroscopic cross sections and lifetimes.

  10. Intermediaries and the Framing of Use-Practices in Design-Use Relations

    DEFF Research Database (Denmark)

    , and of use, various network elements are in flux, serving at times as ‘intermediaries’ (here used in the delimited Actor-Network sense) and other times, as ‘actants’ in networks of relations. The paper grapples with the issue by drawing upon two delimited case studies, dealing with ‘public access......The paper explores how design-use relations – framed and facilitated through intermediary organizations and forms of organizing in the process of technology design as well as use – come to bear upon, yet, in turn, also are qualified through, users and other instances’ engagement through practices...... of domestication. By addressing the issue of intermediary engagements in the exploration and discussion of the role of users, the idea is to shed light on the shifting status and roles of users and other network elements in the hybrid configuration of practice(s). Both as relates to the practices of design...

  11. Do intermediary institutions promote inclusiveness in PES programs? The case of Costa Rica

    DEFF Research Database (Denmark)

    Bosselmann, Aske Skovmand; Lund, Jens Friis

    2013-01-01

    Payments for environmental services (PES) are often promoted on the basis of a purported win–win scenario in terms of accomplishing dual environmental and social policy objectives. Yet, it has been observed that PES programs tend to exclude small land-owners due to relatively high and largely scale......-independent transaction costs. This study seeks to shed light on the role of local intermediaries in PES programs and how they may bring the reality of PES closer to the win–win scenario. This is done through an investigation of three intermediaries in the Costa Rican PES program; an NGO, a producer cooperative......, and a county agricultural center. Based on interviews, household surveys, and reviews of PES contracts, the study examines differences in the inclusion of small-holders in the PES program between the three organizations and focuses on understanding the underlying reasons for any observed differences...

  12. Intermediaries and the Framing of Use-Practices in Design-Use Relations

    DEFF Research Database (Denmark)

    of domestication. By addressing the issue of intermediary engagements in the exploration and discussion of the role of users, the idea is to shed light on the shifting status and roles of users and other network elements in the hybrid configuration of practice(s). Both as relates to the practices of design......, and of use, various network elements are in flux, serving at times as ‘intermediaries’ (here used in the delimited Actor-Network sense) and other times, as ‘actants’ in networks of relations. The paper grapples with the issue by drawing upon two delimited case studies, dealing with ‘public access......-presentation (Law 2002, Cooper 2005). The relevance of intermediaries for design is addressed, where the cases in point show how aspects of use, and hereby the role of users and use-practices, are implicated and distributed through enactments in the heterogeneous orderings and networks of relations in design...

  13. Tensions in firm-community collaboration and the role of intermediaries in exploiting synergies

    DEFF Research Database (Denmark)

    Dragsdahl Lauritzen, Ghita; Salomo, Søren

    2013-01-01

    and as dilemmas relating to power, identity, and competence that must be balanced in order to encourage and benefit from user contributions. Introducing Systems theory this paper shows that what is currently described as dilemmas that must be managed, are in fact paradoxes that are mutually enabling and must...... providers can be identified as a third party playing a substantial role in the management of such tensions, studies describing firmcommunity interaction predominantly overlook the phenomenon of intermediaries. Existing user innovation literature mostly explains the tensions from a user perspective...... be embraced in order to foster innovation. We enrich current understandings of firmcommunity collaborations by exploring the role of intermediaries and their influence on the firm’s ability to attend to competing demands simultaneously...

  14. The role of independent intermediaries. The case of small and medium-sized exporters

    DEFF Research Database (Denmark)

    Madsen, Tage Koed; Moen, Øystein; Hammervold, Randi

    2012-01-01

    The article examines how small and medium-sized exporters collaborate with intermediaries in foreign markets by studying the level of control, i.e. the delegation of decisions rights and task solution. It goes one step further than previous research, since it examines degrees of control and parti......The article examines how small and medium-sized exporters collaborate with intermediaries in foreign markets by studying the level of control, i.e. the delegation of decisions rights and task solution. It goes one step further than previous research, since it examines degrees of control...... export firms are analysed by a structural equation modelling approach. The article provides empirical evidence that managers keep control of decision making to an extent that may have a negative impact on export performance. The empirical study indicates that firms should participate more in task...

  15. Financial intermediaries in Mexico: Possible scenarios within the framework of the NAFTA

    Directory of Open Access Journals (Sweden)

    Antonina Boncheva

    2000-01-01

    Full Text Available The possibility that NAFTA open up for the financial institutions of Canada and the United States to penetrate intro the Mexican market are quite important. Their presence may increase competitiveness in the financial sector by raising and lowering financial margins. This study seeks to analyze the guidelines of the North American Free Trade Agreement in what pertains to the financial institutions. It also takes into account the incidence that the penetration of the latter may have into the Mexican financial market, with a particular emphasis on the non-banking financial intermediaries. The article concludes that with the coming into effect of the North American Free Trade Agreement, a new internationalization phase of the Mexican financial system begins to take shape. This entails the entrance of foreign financial institutions, the majority of which are non-banking financial intermediaries enjoying greater benefits under the regulations of this agreement.

  16. Gaining Relational Competitive Advantages

    DEFF Research Database (Denmark)

    Hu, Yimei; Zhang, Si; Li, Jizhen

    2015-01-01

    Establishing strategic technological partnerships (STPs) with foreign partners is an increasingly studied topic within the innovation management literature. Partnering firms can jointly create sources of relational competitive advantage. Chinese firms often lack research and development (R......&D) capabilities but are increasingly becoming preferred technological partners for transnational corporations. We investigate an STP between a Scandinavian and a Chinese firm and try to explore how to gain relational competitive advantage by focusing on its two essential stages: relational rent generation...

  17. Learn and gain

    CERN Document Server

    Al-Alami, Suhair Eyad Jamal

    2013-01-01

    Initiating the slogan ""love it, live it"", Learn and Gain includes eight short stories, chosen to illustrate various modes of narration, as well as to provoke reflection and discussion on a range of issues. All texts utilized here illustrate how great writers can, with their insight and gift for words, help us to see the world we live in, in new probing and exciting ways. What characterises the book, the author believes, is the integration of the skills of literary competence, communicative c...

  18. Analysis of Intermediary Behavior’s Definition of Market Intermediary Organization%试论市场中介机构之中介行为的定义

    Institute of Scientific and Technical Information of China (English)

    2013-01-01

      伴随着市场中介机构在我国市场经济的高速发展,出现了诸如市场中介机构中介行为难以界定、法律地位模糊、市场地位不明确等问题。要解决这些问题,应建立在准确界定市场中介机构之中介行为的定义的基础之上。%There are so many problems ,such as being difficult to define the market behavior ,legal sta-tus fuzzy and market position indetermination and so on ,accomparying the market intermediary organiza-tion’s high-speed development in the market economy in our country .To solve these problems ,It should be establised on the exact defination of the intermediary behawior in the market .

  19. Intermediary objects in the workspace design process: means of experience transfer in the offshore sector

    DEFF Research Database (Denmark)

    Souza da Conceição, Carolina; Silva, Gislaine; Broberg, Ole

    2012-01-01

    The aim of this paper is to discuss the use of intermediary objects in the workspace design process of offshore accommodations module. The integration of ergonomics in the design process can lead to better work conditions, more effectiveness in the work process and less health and safety issues. ...... at transferring the experience from the use to the design in the specific field of offshore accommodations module....

  20. Digital piracy debunked: a short note on digital threats and intermediary liability

    OpenAIRE

    Giancarlo F. Frosio

    2016-01-01

    In the last two decades, the industry has deployed endlessly the rhetoric of the “digital threat” in order to demand harsher measures against digital piracy. Recently, the “digital threat” discourse called for enhanced liability of online intermediaries, especially those whose platforms may be used to infringe copyright. This short paper shows that the “digital threat” discourse is based on shaky grounds. Two related arguments might run against this approach. First, market conditions might in...

  1. Digital piracy debunked: a short note on digital threats and intermediary liability

    OpenAIRE

    Giancarlo F. Frosio

    2016-01-01

    In the last two decades, the industry has deployed endlessly the rhetoric of the “digital threat” in order to demand harsher measures against digital piracy. Recently, the “digital threat” discourse called for enhanced liability of online intermediaries, especially those whose platforms may be used to infringe copyright. This short paper shows that the “digital threat” discourse is based on shaky grounds. Two related arguments might run against this approach. First, market conditions might in...

  2. The differences between Groupon and other group-buying intermediaries: : from transactional and relational coordination perspectives

    OpenAIRE

    Jia, Yijing; Wu, Qiongshen

    2011-01-01

    Groupon is a popular group-buying website offering daily deals and has experiencedfast growth. It has attracted amounts of imitators and they sprang up all over the world.We treat this phenomenon by taking Groupon as an intermediary executing coordinationbetween merchants and customers in the group-buying activities. To see the particularpractices of Groupon in operating transactional and relational coordination mechanisms,we collect diverse group-buying forms from the earliest buying club si...

  3. Correlates of the Intention to Implement a Tailored Physical Activity Intervention: Perceptions of Intermediaries

    Directory of Open Access Journals (Sweden)

    Denise Peels

    2014-02-01

    Full Text Available The public health impact of health behaviour interventions is highly dependent on large-scale implementation. Intermediaries—intervention providers—determine to a large extent whether an intervention reaches the target population, and hence its impact on public health. A cross-sectional study was performed to identify the correlates of intermediaries’ intention to implement a computer-tailored physical activity intervention. According to theory, potential correlates are intervention characteristics, organisational characteristics, socio-political characteristics and intermediary characteristics. This study investigated whether intermediary characteristics mediated the association between the intervention, organisational and socio-political characteristics and intention to implement the intervention. Results showed that intervention characteristics (i.e., observability (B = 0.53; p = 0.006; relative advantage (B = 0.79; p = 0.020; complexity (B = 0.80; p < 0.001; compatibility (B = 0.70; p < 0.001, organisational characteristics (i.e., type of organization (B = 0.38; p = 0.002; perceived task responsibility (B = 0.66; p ≤ 0.001; capacity (B = 0.83; p < 0.001, and the social support received by intermediary organisations (B = 0.81; p < 0.001 were associated with intention to implement the intervention. These factors should thus be targeted by an implementation strategy. Since self-efficacy and social norms perceived by the intermediary organisations partially mediated the effects of other variables on intention to implement the intervention (varying between 29% and 84%, these factors should be targeted to optimise the effectiveness of the implementation strategy.

  4. Perspectives for Web Service Intermediaries: How Influence on Quality Makes the Difference

    Science.gov (United States)

    Scholten, Ulrich; Fischer, Robin; Zirpins, Christian

    In the service-oriented computing paradigm and the Web service architecture, the broker role is a key facilitator to leverage technical capabilities of loose coupling to achieve organizational capabilities of dynamic customer-provider-relationships. In practice, this role has quickly evolved into a variety of intermediary concepts that refine and extend the basic functionality of service brokerage with respect to various forms of added value like platform or market mechanisms. While this has initially led to a rich variety of Web service intermediaries, many of these are now going through a phase of stagnation or even decline in customer acceptance. In this paper we present a comparative study on insufficient service quality that is arguably one of the key reasons for this phenomenon. In search of a differentiation with respect to quality monitoring and management patterns, we categorize intermediaries into Infomediaries, e-Hubs, e-Markets and Integrators. A mapping of quality factors and control mechanisms to these categories depicts their respective strengths and weaknesses. The results show that Integrators have the highest overall performance, followed by e-Markets, e-Hubs and lastly Infomediaries. A comparative market survey confirms the conceptual findings.

  5. Opportunities of E-Service Providing Intermediaries in Transactions of Business Subjects

    Directory of Open Access Journals (Sweden)

    Dalė Dzemydienė

    2013-08-01

    Full Text Available The aim of this research: to analyze the transaction methods and tools through a virtual intermediary providing electronic services and functions based on virtual agent generated added value to small and medium-sized business enterprises (SMB based on transaction cost theory. Used methodology: through a complex and multi-faceted relationship analysis examining the virtual intermediary services to small and medium-sized enterprises, evaluating their performance, highlighting the added component of the value chain and benefits. The research methodology is based on the scientific literature, generalization and comparative analysis. The practical significance: the activities of business enterprises (corporations, organizations are profitable, if usage of Information and Communication Technologies (ICT is effective. ICT is becoming increasingly important in reducing business operating costs. E-services used in business transactions acquire special significance. European Union (EU in the inner space in more than 20 million of SMEs and their work areas include more than 170 activities. Both internal and external competition encourages SME operators to increase operational efficiency. The article analyzes the cost-cutting options related to services provided by virtual intermediaries and has practical significance in the national and international companies. Originality/value: looking at cost reduction opportunities through a virtual agent functionality and value-added SME operator justification.

  6. Change, Gain and Loss

    Institute of Scientific and Technical Information of China (English)

    Fu Mengzi

    2006-01-01

    @@ Five years have passed since the September 11 terrorist attacks occurred. America's counter-terrorism campaign is still on the way.Besides the momentary monumental significance of the fifth anniversary, five years is still too short in regard to the long-term counter-terrorism campaign. Yet, America's president's tenure is eight years at best; most of Bush's presidency time has passed. Five years ago, the U. S. encountered the most serious terrorist attack; the whole nation formed a consensus that counter-terrorism is its utmost priority. President Bush once enjoyed a support rate as high as 90% for over 16 months. But five years later, the trend changes. People can not help but ask: what are the gains and losses of the Republican Party in dealing with national security affairs?

  7. Gain Efficient L-band EDFA With Dynamic Gain Equalization

    Institute of Scientific and Technical Information of China (English)

    Xiaoli Hui; Rujian Lin

    2003-01-01

    A gain efficient L-band erbium-doped fiber amplifier with dynamic gain equalization is presented. Using a single fiber Bragg grating and a static equalizer, the gain is clamped at 27dB with less than 0.5dB variations over 35nm.

  8. Role of the intermediary in implementation of the principles of sustainable development

    Directory of Open Access Journals (Sweden)

    O.O. Dyma

    2015-12-01

    Full Text Available The aim of the article. Worsening of environmental, social and economic problems require active role of business in solving them. One of the solutions of these problems is the implementation of principles of sustainable development in the practice of the state, business and consumers. Intermediaries should play a key role in this process, as they are an integral part of value creation network. Working in close relationship with producers and customers intermediary organizations can initiate the implementation of sustainable development not only at the macro but also at the micro level. The transition to the practice of sustainable development has a beneficial impact on the society and environment. Moreover, it can also have a positive effect on the intermediaries' financial performance. Adherence to the principles of sustainable development can help companies to achieve competitive advantages. The article is devoted to the peculiarities of sustainable development principles’ implementation by intermediary companies. A set of measures was developed to implement the principles of sustainable development. The results of the analysis. Lack of information is one of the main problems of sustainable development principles. Producers, customers and intermediaries do not have expertise in sustainable development principles’ implementation in the short and long-term perspective. To solve this problem the information system has been developed. The system allows the company to analyze the previous experience and share it with shareholders. The article highlights four groups of innovative activities aimed at achieving sustainable development objectives: activities to improve internal efficiency, new solutions in the field of organization of operations, optimization of product promotion activities as well as new forms of cooperation. Principles of sustainable development can be implemented via improvement of existing practices or completely new solutions

  9. METS as an 'Intermediary' Schema for a Digital Library of Complex Scientific Multimedia

    Directory of Open Access Journals (Sweden)

    Richard Gartner

    2012-09-01

    Full Text Available The use of the Metadata Encoding and Transmission Standard (METS schema as a mechanism for delivering a digital library of complex scientific multimedia is examined as an alternative to the Fedora Content Model (FCM. Using METS as an 'intermediary' schema, where it functions as a template which is populated with content metadata on-the-fly using an XSLT transformation, it is possible to replicate the flexibility of structure and granularity of FCM while avoiding its complexity and often substantial demands on developers.

  10. An intermediary role for the tremorgenic mycotoxin TR-2 in the biosynthesis of verruculogen.

    Science.gov (United States)

    Willingale, J; Perera, K P; Mantle, P G

    1983-09-15

    14C-Labelled compound TR-2, a tremorgenic mycotoxin, was administered to Penicillium raistrickii in submerged fermentation. Half of the added radiolabel was taken up by the fungus during the 60 h incubation period and the secondary metabolites subsequently isolated, principally verruculogen but also fumitremorgin B, were found to be radiolabelled. The efficiency of biosynthetic incorporation of TR-2 into verruculogen within the mycelium was at least 35%, demonstrating for the first time an intermediary role for TR-2. Fumitremorgin B was also TR-2-derived but may not be an important intermediate in verruculogen biosynthesis.

  11. Leading Gainful Employment Metric Reporting

    Science.gov (United States)

    Powers, Kristina; MacPherson, Derek

    2016-01-01

    This chapter will address the importance of intercampus involvement in reporting of gainful employment student-level data that will be used in the calculation of gainful employment metrics by the U.S. Department of Education. The authors will discuss why building relationships within the institution is critical for effective gainful employment…

  12. Noise Gain Features of Fiber Raman Amplifier

    Directory of Open Access Journals (Sweden)

    Georgii S. Felinskyi

    2016-01-01

    Full Text Available The formation dynamics of the optical noise in a silica single mode fiber (SMF as function of the pump power variation in the counter pumped fiber Raman amplifier (FRA is experimentally studied. The ratio between the power of amplified spontaneous emission and the power of incoherent optical noise is quantitatively determined by detailed analysis of experimental data in the pump powers range of 100–300 mW within the full band of Stokes frequencies, including FRA working wavelengths over the C + L transparency windows. It is found out the maximum of Raman gain coefficient for optical noise does not exceed ~60% of corresponding peak at the gain profile maximum of coherent signal. It is shown that the real FRA noise figure may be considerably less than 3 dB over a wide wavelength range (100 nm at a pump power of several hundreds of mW.

  13. The Zebrafish moonshine Gene Encodes Transcriptional Intermediary Factor 1γ, an Essential Regulator of Hematopoiesis

    Science.gov (United States)

    Ransom, David G; Bahary, Nathan; Niss, Knut; Traver, David; Burns, Caroline; Trede, Nikolaus S; Paffett-Lugassy, Noelle; Saganic, Walter J; Lim, C. Anthoney; Hersey, Candace; Zhou, Yi; Barut, Bruce A; Lin, Shuo; Kingsley, Paul D; Palis, James; Orkin, Stuart H

    2004-01-01

    Hematopoiesis is precisely orchestrated by lineage-specific DNA-binding proteins that regulate transcription in concert with coactivators and corepressors. Mutations in the zebrafish moonshine (mon) gene specifically disrupt both embryonic and adult hematopoiesis, resulting in severe red blood cell aplasia. We report that mon encodes the zebrafish ortholog of mammalian transcriptional intermediary factor 1γ (TIF1γ) (or TRIM33), a member of the TIF1 family of coactivators and corepressors. During development, hematopoietic progenitor cells in mon mutants fail to express normal levels of hematopoietic transcription factors, including gata1, and undergo apoptosis. Three different mon mutant alleles each encode premature stop codons, and enforced expression of wild-type tif1γ mRNA rescues embryonic hematopoiesis in homozygous mon mutants. Surprisingly, a high level of zygotic tif1γ mRNA expression delineates ventral mesoderm during hematopoietic stem cell and progenitor formation prior to gata1 expression. Transplantation studies reveal that tif1γ functions in a cell-autonomous manner during the differentiation of erythroid precursors. Studies in murine erythroid cell lines demonstrate that Tif1γ protein is localized within novel nuclear foci, and expression decreases during erythroid cell maturation. Our results establish a major role for this transcriptional intermediary factor in the differentiation of hematopoietic cells in vertebrates. PMID:15314655

  14. The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis.

    Directory of Open Access Journals (Sweden)

    David G Ransom

    2004-08-01

    Full Text Available Hematopoiesis is precisely orchestrated by lineage-specific DNA-binding proteins that regulate transcription in concert with coactivators and corepressors. Mutations in the zebrafish moonshine (mon gene specifically disrupt both embryonic and adult hematopoiesis, resulting in severe red blood cell aplasia. We report that mon encodes the zebrafish ortholog of mammalian transcriptional intermediary factor 1gamma (TIF1gamma (or TRIM33, a member of the TIF1 family of coactivators and corepressors. During development, hematopoietic progenitor cells in mon mutants fail to express normal levels of hematopoietic transcription factors, including gata1, and undergo apoptosis. Three different mon mutant alleles each encode premature stop codons, and enforced expression of wild-type tif1gamma mRNA rescues embryonic hematopoiesis in homozygous mon mutants. Surprisingly, a high level of zygotic tif1gamma mRNA expression delineates ventral mesoderm during hematopoietic stem cell and progenitor formation prior to gata1 expression. Transplantation studies reveal that tif1gamma functions in a cell-autonomous manner during the differentiation of erythroid precursors. Studies in murine erythroid cell lines demonstrate that Tif1gamma protein is localized within novel nuclear foci, and expression decreases during erythroid cell maturation. Our results establish a major role for this transcriptional intermediary factor in the differentiation of hematopoietic cells in vertebrates.

  15. Gene expression analysis of a critical enzyme in intermediary metabolism in oyster pathogen Perkinsus marinus .

    Science.gov (United States)

    Noell, K.

    2016-02-01

    A key regulatory component in the Krebs cycle pathway is the mitochondrial aconitase enzyme which has been posited to balance energy needs and oxidative growth total storage via citrate utilization. The presence of a cytosolic aconitase (cAcon) activity which serves as a competitor for citrate substrate has been recognized for years. cAcon is a dual function protein with mutually exclusive roles as a post transcriptional regulator of animal cell iron metabolism or as the cytosolic isoform of the iron sulfur enzyme aconitase. We are interested in establishing the role of this orthologue in Perkinsus marnius metabolism through demonstrating its function as aconitase, by looking at gene expression under certain environmental conditions. P. marinus is a close evolutionary relative of the dinoflagellates and is the causative agent of Dermo disease, which has significantly impacted oyster populations along the eastern seaboard. An understanding of intermediary metabolism will yield important insights into how c-aconitase may be involved in stress response systems such as oxidative tension and metabolite deficiency, which could be used to help aquaculturists alleviate the severe impact of "dermo" on the on the oyster population. This study will present data regarding our preliminary analysis of the gene aconitase and its role in intermediary metabolism.

  16. Trade associations and labor organizations as intermediaries for disseminating workplace safety and health information.

    Science.gov (United States)

    Okun, Andrea H; Watkins, Janice P; Schulte, Paul A

    2017-09-01

    There has not been a systematic study of the nature and extent to which business and professional trade associations and labor organizations obtain and communicate workplace safety and health information to their members. These organizations can serve as important intermediaries and play a central role in transferring this information to their members. A sample of 2294 business and professional trade associations and labor organizations in eight industrial sectors identified by the National Occupational Research Agenda was surveyed via telephone. A small percent of these organizations (40.9% of labor organizations, 15.6% of business associations, and 9.6% of professional associations) were shown to distribute workplace safety and health information to their members. Large differences were also observed between industrial sectors with construction having the highest total percent of organizations disseminating workplace safety and health information. There appears to be significant potential to utilize trade and labor organizations as intermediaries for transferring workplace safety and health information to their members. Government agencies have a unique opportunity to partner with these organizations and to utilize their existing communication channels to address high risk workplace safety and health concerns. Published 2017. This article is a U.S. Government work and is in the public domain in the USA.

  17. Gain Flattening Filter Canceling Temperature Dependence of EDFA s gain

    Institute of Scientific and Technical Information of China (English)

    M.; Ohmura; Y.; Ishizawa; H.; Nakaji; K.; Hashimoto; T.; Shibata; M.; Shigehara; A.; Inoue

    2003-01-01

    We have developed a gain flattening filter (GFF) for an erbium doped fiber (EDF) without temperature control systems. This GFF, which consists of temperature-sensitive long period gratings (LPGs) and a temperature compensated slanted fiber Bragg grating (SFBG), follows the gain shift of EDF with temperature. Gain variation of the EDFA less than 0.25dBp-p was achieved with the bandwidth of 37nm, and the temperature range 0-65℃ without any temperature control systems.

  18. Measuring the gain dynamics in a conjugated polymer film

    CERN Document Server

    Van den Berg, S A; Hooft, G W; Eliel, E R

    2004-01-01

    We present a simple method for measuring the gain decay time in a conjugated polymer film by optically exciting the film with two mutually delayed ultrashort pump pulses. When the pump is set at such a power level that amplified spontaneous emission marginally develops along the polymer waveguide, the total output emitted from its edge decays exponentially as a function of the interpulse delay. The corresponding decay time represents the decay time of the gain of the polymer material.

  19. Gain saturation in InGaN superluminescent diodes

    Science.gov (United States)

    Kafar, Anna; Stanczyk, Szymon; Targowski, Grzegorz; Suski, Tadek; Perlin, Piotr

    2014-03-01

    The gain saturation is a crucial factor limiting achievable output power of superluminescent diodes (SLD), as it exponentially depends on optical gain value. Contrary to laser diodes, in SLDs gain is increasing with the increasing current even much above the transparency conditions. Therefore, SLDs provide us with an unique possibility to examine gain under high current densities (high carrier injection). In our work we examined SLDs fabricated in a "j-shape" ridge-waveguide geometry having chips of the length of 700 μm and 1000 μm, emitting in the blue-violet region. By comparing the amplified spontaneous emission measured along the device waveguide with true spontaneous emission measured in perpendicular direction, we are able to extract optical gain as a function of injected current. We show, that in our devices spontaneous emission exhibits a square-root-like dependence on current which is commonly associated with the presence of "droop" in case of nitride light emitting diodes. However, along the waveguide axis, fast processes of stimulated recombination dominate which eliminates the efficiency reduction. Calculated optical gain shows a substantial saturation for current densities above 8 kA/cm2.

  20. Phonon-assisted gain in a semiconductor double quantum dot maser.

    Science.gov (United States)

    Gullans, M J; Liu, Y-Y; Stehlik, J; Petta, J R; Taylor, J M

    2015-05-15

    We develop a microscopic model for the recently demonstrated double-quantum-dot maser. In characterizing the gain of this device we find that, in addition to the direct stimulated emission of photons, there is a large contribution from the simultaneous emission of a photon and a phonon, i.e., the phonon sideband. We show that this phonon-assisted gain typically dominates the overall gain, which leads to masing. Recent experimental data are well fit with our model.

  1. Assessing Institutional Characteristics on Microcredit Default in Kenya: A Comparative Analysis of Microfinance Institutions and Financial Intermediaries

    Science.gov (United States)

    Muthoni, Muturi Phyllis

    2016-01-01

    A major concern on microcredit repayment remains a major obstacle to the Micro Financial Institutions (MFIs) and Financial Intermediaries (FIs) in Kenya. The health of MFI sector in Sub Sahara Africa (SSA) is a cause of concern due to the increased portfolio at risk (PAR). This region records the highest risk globally with its PAR 30 greater than…

  2. Assessing Borrower's and Business' Factors Causing Microcredit Default in Kenya: A Comparative Analysis of Microfinance Institutions and Financial Intermediaries

    Science.gov (United States)

    Muthoni, Muturi Phyllis

    2016-01-01

    A major concern on microcredit repayment remains a major obstacle to the Micro Financial Institutions (MFIs) and Financial Intermediaries (FIs) in Kenya. The health of MFI sector in Sub Sahara Africa (SSA) is a cause of concern due to the increased portfolio at risk (PAR). This region records the highest risk globally. Its PAR 30 is greater than 5…

  3. Information Technology and Aerospace Knowledge Diffusion: Exploring the Intermediary-End User Interface in a Policy Framework.

    Science.gov (United States)

    Pinelli, Thomas E.; And Others

    1992-01-01

    Discusses U.S. technology policy and the transfer of scientific and technical information (STI). Results of a study of knowledge diffusion in the aerospace industry are reported, including data on aerospace information intermediaries, use of computer and information technologies, and the use of NASA (National Aeronautics and Space Administration)…

  4. Beyond knowledge brokering: an exploratory study on innovation intermediaries in an evolving smallholder agricultural system in Kenya

    NARCIS (Netherlands)

    Kilelu, C.W.; Klerkx, L.W.A.; Leeuwis, C.; Hall, A.

    2011-01-01

    The recognition that innovation occurs in networks of heterogeneous actors and requires broad systemic support beyond knowledge brokering has resulted in a changing landscape in the intermediary domain in the increasingly market-driven agricultural sector in developing countries. This paper presents

  5. Intermediaries in the ‘Design for Sustainability’ Field: Strategies for Developing Innovation Support Mechanisms in Turkey

    NARCIS (Netherlands)

    Küçüksayraç, E.

    2015-01-01

    Design for sustainability is a key approach for achieving sustainable development. This PhD study investigates innovation support for companies working on design for sustainability and intermediaries that provide innovation support. The study focuses on Turkey, where design for sustainability is not

  6. Providing Spark and Stability: The Role of Intermediary Organizations in Establishing School-Based Youth-Adult Partnerships

    Science.gov (United States)

    Mitra, Dana L.; Sanders, Felicia C.; Perkins, Daniel F.

    2010-01-01

    The term "youth-adult partnership" increasingly is being used to define a relationship in which both youth and adults have the potential to contribute to decision making processes, to learn from one another, and to promote change. Establishing a relationship with an "intermediary organization" can provide much needed stability and sustainability…

  7. Beyond knowledge brokerage: an exploratory study of innovation intermediaries in an evolving smallholder agricultural system in Kenya

    NARCIS (Netherlands)

    Kilelu, C.W.; Klerkx, L.W.A.; Leeuwis, C.; Hall, A.

    2011-01-01

    The recognition that innovation occurs in networks of heterogeneous actors and requires broad systemic support beyond knowledge brokering has resulted in a changing landscape of the intermediary domain in an increasingly market-driven agricultural sector in developing countries. This paper presents

  8. Sketching the outline of a ghost: the fair balance between copyright and fundamental rights in intermediary third party liability

    NARCIS (Netherlands)

    Angelopoulos, C.

    2015-01-01

    Purpose - The purpose of this article is to analyse the concept of a fair balance between conflicting fundamental rights in the context of intermediary liability for third party copyright infringement. Design/methodology/approach - European Legal Method. Findings - Fair balance is the appropriate

  9. Gain Flattening Filter Canceling Temperature Dependence of EDFA's gain

    Institute of Scientific and Technical Information of China (English)

    M. Ohmura; Y. Ishizawa; H. Nakaji; K. Hashimoto; T. Shibata; M. Shigehara; A. Inoue

    2003-01-01

    We have developed a gain flattening filter(GFF) for an erbium doped fiber (EDF) without temperature control systems. This GFF, which consists of temperature-sensitive long period gratings (LPGs)and a temperature compensated slanted fiber Bragg grating (SFBG), follows the gain shift of EDF with temperature. Gain variation of the EDFA less than 0.25dBp-p was achieved with the bandwidth of 37nm,and the temperature range 0-65℃ without and temperature control systems.

  10. Development of Capital Markets in Turkey and Analysis of Financial Structure of the Intermediary Institutions

    Directory of Open Access Journals (Sweden)

    Fikret Kartal

    2013-08-01

    Full Text Available Capital markets, where demand and supply for medium to long term finance meet, are more active and efficient in higher income countries. Capital markets are insufficiently developed in emerging countries such as Turkey that have the structural and institutional obstacles and lack of capital. The first market with securities was established in 19th century in the Ottoman Empire; the Turkish capital markets have gone through the reform programmes as a part of liberalization started in 1980; but the banking sector constitutes the biggest part of the financial sector. The paper presents the development of capital markets in Turkey and analyzes the intermediary institutions by using the financial statements and ratios for the period December 2007-December 2011.

  11. Communication models of institutional online communities: the role of the ABC cultural intermediary

    Directory of Open Access Journals (Sweden)

    Jonathon Hutchinson

    2013-10-01

    Full Text Available The co­-creation of cultural artefacts has been democratised given the recent technological affordances of information and communication technologies. Web 2.0 technologies have enabled greater possibilities of citizen inclusion within the media conversations of their nations. For example, the Australian audience has more opportunities to collaboratively produce and tell their story to a broader audience via the public service media (PSM facilitated platforms of the Australian Broadcasting Corporation (ABC. However, providing open collaborative production for the audience gives rise to the problem: how might the PSM manage the interests of all the stakeholders and align those interests with its legislated Charter? This paper considers this problem through the ABC's user­ created content participatory platform, ABC Pool and highlights the cultural intermediary as the role responsible for managing these tensions. This paper also suggests cultural intermediation is a useful framework for other media organisations engaging in co­creative activities with their audiences.

  12. The role of intermediaries in the synchronization of pulse-coupled oscillators

    Science.gov (United States)

    García, R. A.; Rubido, N.; Martí, A. C.; Cabeza, C.

    2014-12-01

    The role of intermediaries in the synchronization of small groups of light controlled oscillators (LCO) is addressed. A single LCO is a two-time-scale phase oscillator. When pulse-coupling two LCOs, the synchronization time decreases monotonously as the coupling strength increases, independent of the initial conditions and frequency detuning. In this work we study numerically the effects that a third LCO induces to the collective behavior of the system. We analyze the new system by dealing with directed heterogeneous couplings among the units. We report a novel and robust phenomenon, absent when coupling two LCOs, which consists of a discontinuous relationship between the synchronization time and coupling strength or initial conditions. The mechanism responsible for the appearance of such discontinuities is discussed.

  13. Absorption and Intermediary Metabolism of Purines and Pyrimidines in Lactating Dairy Cows

    DEFF Research Database (Denmark)

    Nielsen, Charlotte Stentoft; Røjen, Betina Amdisen; Jensen, Søren Krogh

    2015-01-01

    About 20 % of ruminal microbial N in dairy cows derives from purines and pyrimidines; however, their intermediary metabolism and contribution to the overall N metabolism has sparsely been described. In the present study, the postprandial patterns of net portal-drained viscera (PDV) and hepatic...... metabolism were assessed to evaluate purine and pyrimidine N in dairy cows. Blood was sampled simultaneously from four veins with eight hourly samples from four multi-catheterised Holstein cows. Quantification of twenty purines and pyrimidines was performed with HPLC–MS/MS, and net fluxes were estimated...... across the PDV, hepatic tissue and total splanchnic tissue (TSP). Concentration differences between veins of fifteen purine and pyrimidine nucleosides (NS), bases (BS) and degradation products (DP) were different from zero (P≤ 0·05), resulting in the net PDV releases of purine NS (0·33–1·3 mmol...

  14. Empirical Analysis on the Financial Intermediary Development and the Economic Fluctuation in China%金融中介发展与中国宏观经济波动实证分析

    Institute of Scientific and Technical Information of China (English)

    杨海燕

    2005-01-01

    This article analyzes the relationship between financial intermediary development and economic fluctuation in the last 50 years in China. It was found that a steady and long-term relation existed between these two variables, and that different aspects of the development of the financial intermediary system had different effects on the economic fluctuation. The improvement of the intermediary's efficiency can repress the economic fluctuation, but the increase of financial intermediaries can intensify the fluctuation. On that basis, some suggestions about the development of the financial intermediary are proposed in this essay.

  15. Toward the extension of obligations to other intermediaries in the internet

    Directory of Open Access Journals (Sweden)

    Ernesto Rengifo García

    2014-12-01

    Full Text Available It is well known that the copy diminishes the individual value of the creation and discourages the effort of the creator. Because of this, the responsibility of internet service providers (ISP concerning copyright infringement by their users has been a subject of great controversy for more than a decade. This discussion has led to a consensus in the sense that the ISP will not be responsible when their participation in the infringement is limited to transmitting, linking, caching, and disseminating information generated by third parties, as long as other requirements are met, such as adopting and communicating policies intended to prevent infringements. However, the development of new business models and the expansion of services available online have raised the question of whether it is possible to extend the secondary or indirect liability regime to other intermediaries such as internet advertising services and financial transaction providers. In order to analyze the liability regimes that could be applied to these intermediaries,¡ it is important to take into account the following points, which will be developed in this paper: i to understand the operation of online advertising and payments and the economic magnitude of these businesses, ii to understand the liability regime presently applied to the isp, iii to study the objections that have been raised against the extension of such regime to online advertising and financial transaction providers, and finally, iv to analyze how through recent legislative initiatives such as the proposed PIPA, SOPA, and open bills in the United States, efforts have been undertaken to overcome the objections and to offer effective and expeditious mechanisms to protect copyright in the internet.

  16. 2-甲基丁酸对西门塔尔牛增重、日粮养分消化和甲烷排放的影响%Effects of 2-methylbutyrate on Daily Gain,Dietary Nutrient Digestion and Methane Emissions in Simmental Cattle

    Institute of Scientific and Technical Information of China (English)

    郭建兵; 王聪; 王江琴

    2016-01-01

    试验旨在研究2‐甲基丁酸对西门塔尔牛日粮养分消化率、增重性能及甲烷排放的影响。选择12月龄左右、发育正常及体重相近的西门塔尔公牛36头,随机分为4组,即对照组及试验1~3组,每组9头牛,分别饲喂添加0、1.0、2.0及3.0 g/kg体重2‐甲基丁酸的玉米秸秆日粮,测定日粮养分消化率、西门塔尔牛增重性能及甲烷的排放情况。试验期70 d。结果表明,试验2、3组西门塔尔牛有机物质(OM )消化率较对照组显著提高(P<0.05);3个试验组粗蛋白质(CP)消化率均较对照组显著提高(P<0.05),但无氮浸出物(NFE)消化率在各组间差异不显著(P>0.05);试验2组西门塔尔牛中性洗涤纤维(NDF)消化率显著高于对照组和试验1组(P<0.05),而其酸性洗涤纤维(ADF)消化率则显著高于其他各组(P<0.05);试验2、3组西门塔尔牛试验期间平均日增重显著高于对照组(P<0.05),但其在试验1组与对照组间差异不显著(P>0.05);与对照组相比,试验2组的干物质采食量显著降低(P<0.05),试验2、3组料重比也显著降低(P<0.05);在日粮中添加2‐甲基丁酸后,西门塔尔牛的甲烷排放呈降低趋势,试验2、3组排放的甲烷能显著低于对照组( P<0.05)。由以上结果推断,在日粮中添加2‐甲基丁酸可促进西门塔尔牛的生长及对营养物质消化,同时可有效降低甲烷排放,2‐甲基丁酸的适宜添加水平为2.0 g/kg体重。%The objective of this study was to evaluate the effects of 2‐methylbutyrate on daily gain ,dietary nutrient digestion and methane emissions in Simmental cattle .Thirty‐six Simmental cattle (12‐month‐old) consuming a corn straw diet were divided randomly into four groups (con‐trol group ,experimental groups 1 ,2 and 3) and supplemented with four levels of 2‐methylbutyrate as 0 ,1 .0 ,2

  17. Diversity Gain through Antenna Blocking

    Directory of Open Access Journals (Sweden)

    V. Dehghanian

    2012-01-01

    Full Text Available As part of the typical usage mode, interaction between a handheld receiver antenna and the operator's RF absorbing body and nearby objects is known to generate variability in antenna radiation characteristics through blocking and pattern changes. It is counterintuitive that random variations in blocking can result in diversity gain of practical applicability. This diversity gain is quantified from a theoretical and experimental perspective. Measurements carried out at 1947.5 MHz verify the theoretical predictions, and a diversity gain of 3.1 dB was measured through antenna blocking and based on the utilized measurement setup. The diversity gain can be exploited to enhance signal detectability of handheld receivers based on a single antenna in indoor multipath environments.

  18. Developmental gains in visuospatial memory predict gains in mathematics achievement.

    Science.gov (United States)

    Li, Yaoran; Geary, David C

    2013-01-01

    Visuospatial competencies are related to performance in mathematical domains in adulthood, but are not consistently related to mathematics achievement in children. We confirmed the latter for first graders and demonstrated that children who show above average first-to-fifth grade gains in visuospatial memory have an advantage over other children in mathematics. The study involved the assessment of the mathematics and reading achievement of 177 children in kindergarten to fifth grade, inclusive, and their working memory capacity and processing speed in first and fifth grade. Intelligence was assessed in first grade and their second to fourth grade teachers reported on their in-class attentive behavior. Developmental gains in visuospatial memory span (d = 2.4) were larger than gains in the capacity of the central executive (d = 1.6) that in turn were larger than gains in phonological memory span (d = 1.1). First to fifth grade gains in visuospatial memory and in speed of numeral processing predicted end of fifth grade mathematics achievement, as did first grade central executive scores, intelligence, and in-class attentive behavior. The results suggest there are important individual differences in the rate of growth of visuospatial memory during childhood and that these differences become increasingly important for mathematics learning.

  19. Developmental gains in visuospatial memory predict gains in mathematics achievement.

    Directory of Open Access Journals (Sweden)

    Yaoran Li

    Full Text Available Visuospatial competencies are related to performance in mathematical domains in adulthood, but are not consistently related to mathematics achievement in children. We confirmed the latter for first graders and demonstrated that children who show above average first-to-fifth grade gains in visuospatial memory have an advantage over other children in mathematics. The study involved the assessment of the mathematics and reading achievement of 177 children in kindergarten to fifth grade, inclusive, and their working memory capacity and processing speed in first and fifth grade. Intelligence was assessed in first grade and their second to fourth grade teachers reported on their in-class attentive behavior. Developmental gains in visuospatial memory span (d = 2.4 were larger than gains in the capacity of the central executive (d = 1.6 that in turn were larger than gains in phonological memory span (d = 1.1. First to fifth grade gains in visuospatial memory and in speed of numeral processing predicted end of fifth grade mathematics achievement, as did first grade central executive scores, intelligence, and in-class attentive behavior. The results suggest there are important individual differences in the rate of growth of visuospatial memory during childhood and that these differences become increasingly important for mathematics learning.

  20. Potential gains from CO2 trading in the EU

    DEFF Research Database (Denmark)

    Svendsen, Gert Tinggaard; Vesterdal, Morten

    2003-01-01

    A new Green Paper from the European Commission on emissions trading foresees the setting-up of a CO2 trading system within the EU for the energy sector. Because any such international environmental agreement is self-enforcing, the participants must have an economic net gain from joining...... the proposed system. Our contribution is therefore to follow the Green Paper proposal and investigate whether member countries and the largest industrial boilers in the electricity sector actually will get significant net gains from CO2 trade in the European Union rather than undertaking domestic actions...... solely. We show, based on PRIMES model, that a full CO2 emission trading system between Annex B countries suggest overall cost savings in the order of 40 % compared to a situation with no trading at all between Member States. A tradable CO2 permit scheme with comprehensive coverage of emissions within...

  1. Potential gains from CO2 trading in the EU

    DEFF Research Database (Denmark)

    Svendsen, Gert Tinggaard; Vesterdal, Morten

    2003-01-01

    A new Green Paper from the European Commission on emissions trading foresees the setting-up of a CO2 trading system within the EU for the energy sector. Because any such international environmental agreement is self-enforcing, the participants must have an economic net gain from joining...... the proposed system. Our contribution is therefore to follow the Green Paper proposal and investigate whether member countries and the largest industrial boilers in the electricity sector actually will get significant net gains from CO2 trade in the European Union rather than undertaking domestic actions...... solely. We show, based on PRIMES model, that a full CO2 emission trading system between Annex B countries suggest overall cost savings in the order of 40 % compared to a situation with no trading at all between Member States. A tradable CO2 permit scheme with comprehensive coverage of emissions within...

  2. Unity gain and non-unity gain quantum teleportation

    CERN Document Server

    Bowen, W P; Buchler, B C; Schnabel, R; Ralph, T C; Symul, T; Lam, P K

    2003-01-01

    We investigate continuous variable quantum teleportation. We discuss the methods presently used to characterize teleportation in this regime, and propose an extension of the measures proposed by Grangier and Grosshans \\cite{Grangier00}, and Ralph and Lam \\cite{Ralph98}. This new measure, the gain normalized conditional variance product $\\mathcal{M}$, turns out to be highly significant for continuous variable entanglement swapping procedures, which we examine using a necessary and sufficient criterion for entanglement. We elaborate on our recent experimental continuous variable quantum teleportation results \\cite{Bowen03}, demonstrating success over a wide range of teleportation gains. We analyze our results using fidelity; signal transfer, and the conditional variance product; and a measure derived in this paper, the gain normalized conditional variance product.

  3. Simplified ASE correction algorithm for variable gain-flattened erbium-doped fiber amplifier.

    Science.gov (United States)

    Mahdi, Mohd Adzir; Sheih, Shou-Jong; Adikan, Faisal Rafiq Mahamd

    2009-06-08

    We demonstrate a simplified algorithm to manifest the contribution of amplified spontaneous emission in variable gain-flattened Erbium-doped fiber amplifier (EDFA). The detected signal power at the input and output ports of EDFA comprises of both signal and noise. The generated amplified spontaneous emission from EDFA cannot be differentiated by photodetector which leads to underestimation of the targeted gain value. This gain penalty must be taken into consideration in order to obtain the accurate gain level. By taking the average gain penalty within the dynamic gain range, the targeted output power is set higher than the desired level. Thus, the errors are significantly reduced to less than 0.15 dB from 15 dB to 30 dB desired gain values.

  4. Tourism Relationship Model and Intermediary for Sustainable Tourism Management : Case Study of the Kiritappu Wetland Trust in Hamanaka, Hokkaido

    OpenAIRE

    Shikida, Asami; Yoda, Mami; KINO, Akiko; Morishige, Masayuki

    2009-01-01

    This paper proposes a simple model that depicts the relationship between community and extra-community stakeholders that will enable the effective development of sustainable tourism. "Sustainable tourism" in this paper is defined as tourism that utilizes community resources for tourism development and re-invests the returns from tourism to the destination resources. The tourism relationship model, with a community-based intermediary as its subsystem, is introduced and applied to a case in Hok...

  5. Welfare Gains from Financial Liberalization.

    Science.gov (United States)

    Townsend, Robert M; Ueda, Kenichi

    2010-08-01

    Financial liberalization has been a controversial issue, as empirical evidence for growth enhancing effects is mixed. Here, we find sizable welfare gains from liberalization (cost to repression), though the gain in economic growth is ambiguous. We take the view that financial liberalization is a government policy that alters the path of financial deepening, while financial deepening is endogenously chosen by agents given a policy and occurs in transition towards a distant steady state. This history-dependent view necessitates the use of simulation analysis based on a growth model. Our application is a specific episode: Thailand from 1976 to 1996.

  6. Clinical performance of a nanofilled resin composite with and without an intermediary layer of flowable composite: a 2-year evaluation.

    Science.gov (United States)

    Stefanski, Sebastian; van Dijken, Jan W V

    2012-02-01

    The objective of this prospective clinical follow-up was to evaluate the 2-year clinical performance of a nanofilled resin composite in class II restorations. The restorations were made with and without intermediary layer of a nanofilled flowable resin composite studied in an intraindividual comparison. Each participant received at least two, as similar as possible, class II restorations of the nanofilled resin composite. One restoration of each pair (54) was chosen at random to be restored with an intermediary layer with flowable nanofilled resin composite. The other was restored without. The restorations were evaluated with slightly modified US Public Health Services criteria at baseline, 1, and 2 years. Ninety-two restorations, 46 pairs, were evaluated at 2 years. A prediction of the caries risk showed that 22 of the evaluated 48 patients were considered as high-risk patients. Two failures were observed, one in each group, resulting in a 2.2% failure rate. No statistical difference was seen between the restorations restored with and without layer of flowable resin composite. The nanofilled resin composite showed very good surface characteristics and color match, which did not change significantly during the follow-up period. The nanofilled resin composite showed a good clinical performance with a 2.2% failure rate after 2 years. No differences were observed between the restorations with and without the nanofilled flowable resin intermediary layer.

  7. Comparative proteomics of seed maturation in oilseeds reveals differences in intermediary metabolism.

    Science.gov (United States)

    Hajduch, Martin; Matusova, Radoslava; Houston, Norma L; Thelen, Jay J

    2011-05-01

    Proteomics is increasingly being used to understand enzyme expression and regulatory mechanisms involved in the accumulation of storage reserves in crops with sequenced genomes. During the past six years, considerable progress has been made to characterize proteomes of both mature and developing seeds, particularly oilseeds - plants which accumulate principally oil and protein as storage reserves. This review summarizes the emerging proteomics data, with emphasis on seed filling in soy, rapeseed, castor and Arabidopsis as each of these oilseeds were analyzed using very similar proteomic strategies. These parallel studies provide a comprehensive view of source-sink relationships, specifically sucrose assimilation into organic acid intermediates for de novo amino acid and fatty acid synthesis. We map these biochemical processes for seed maturation and illustrate the differences and similarities among the four oilseeds. For example, while the four oilseeds appear capable of producing cytosolic phosphoenolpyruvate as the principal carbon intermediate, soybean and castor also express malic enzymes and malate dehydrogenase, together capable of producing malate that has been previously proposed to be the major intermediate for fatty acid synthesis in castor. We discuss these and other differences in the context of intermediary metabolism for developing oilseeds. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. Relationship between Structural and Intermediary Determinants of Health and Preterm Delivery

    Science.gov (United States)

    Dolatian, Mahrokh; Mirabzadeh, Arash; Forouzan, Ameneh Setareh; Sajjadi, Homeira; Alavimajd, Hamid; Mahmoodi, Zohreh; Moafi, Farnoosh

    2014-01-01

    Background Preterm birth is a major health problem that leads to infant morbidity and mortality. The main goal of this study was to find the relationship between social determinants of health and preterm delivery. Methods A prospective longitudinal cohort study was carried out on 500 pregnant women in their 24th to 28th gestational weeks in 2012. The pregnant women filled out a self-report questionnaire on the structural determinant, perceived stress, and perceived social support. The participants were followed up until labor and the data about mother and the newborn were collected after labor. The data were analyzed by SPSS 21 and Lisrel 8.8 software programs using pathway analysis. Results The final path model fit well (CFI=0.96; RMSEA=0.060). Path analysis showed that among structural factors, income had a direct effect (β=0.06) and the factors of income (β=0.00594), number of children (family size) (β=-0.024), as well as mother's education (β=-0.0084) had the greatest overall effect on gestational age at birth respectively. Also, the results showed that among intermediate factors of social determinants of health, stress in the direct path (β=-0.12) and among the overall effects, the perceived stress (β=-0.12) and perceived social support (β=0.0396) affected the gestational age at birth. Conclusion The current study showed that some structural and intermediary determinants such as income and perceived stress had an effect on preterm labor. PMID:24918080

  9. Data ideologies of an interested public: A study of grassroots open government data intermediaries

    Directory of Open Access Journals (Sweden)

    Andrew Schrock

    2017-01-01

    Full Text Available Government officials claim open data can improve internal and external communication and collaboration. These promises hinge on “data intermediaries”: extra-institutional actors that obtain, use, and translate data for the public. However, we know little about why these individuals might regard open data as a site of civic participation. In response, we draw on Ilana Gershon to conceptualize culturally situated and socially constructed perspectives on data, or “data ideologies.” This study employs mixed methodologies to examine why members of the public hold particular data ideologies and how they vary. In late 2015 the authors engaged the public through a commission in a diverse city of approximately 500,000. Qualitative data was collected from three public focus groups with residents. Simultaneously, we obtained quantitative data from surveys. Participants’ data ideologies varied based on how they perceived data to be useful for collaboration, tasks, and translations. Bucking the “geek” stereotype, only a minority of those surveyed (20% were professional software developers or engineers. Although only a nascent movement, we argue open data intermediaries have important roles to play in a new political landscape.

  10. The translation of sports injury prevention and safety promotion knowledge: insights from key intermediary organisations.

    Science.gov (United States)

    Bekker, Sheree; Paliadelis, Penny; Finch, Caroline F

    2017-03-28

    A recognised research-to-practice gap exists in the health research field of sports injury prevention and safety promotion. There is a need for improved insight into increasing the relevancy, accessibility and legitimacy of injury prevention and safety promotion research knowledge for sport settings. The role of key organisations as intermediaries in the process of health knowledge translation for sports settings remains under-explored, and this paper aims to determine, and describe, the processes of knowledge translation undertaken by a set of key organisations in developing and distributing injury prevention and safety promotion resources. The National Guidance for Australian Football Partnerships and Safety (NoGAPS) project provided the context for this study. Representatives from five key NoGAPS organisations participated in individual face-to-face interviews about organisational processes of knowledge translation. A qualitative descriptive methodology was used to analyse participants' descriptions of knowledge translation activities undertaken at their respective organisations. Several themes emerged around health knowledge translation processes and considerations, including (1) identifying a need for knowledge translation, (2) developing and disseminating resources, and (3) barriers and enablers to knowledge translation. This study provides insight into the processes that key organisations employ when developing and disseminating injury prevention and safety promotion resources within sport settings. The relevancy, accessibility and legitimacy of health research knowledge is foregrounded, with a view to increasing the influence of research on the development of health-related resources suitable for community sport settings.

  11. Digital piracy debunked: a short note on digital threats and intermediary liability

    Directory of Open Access Journals (Sweden)

    Giancarlo F. Frosio

    2016-03-01

    Full Text Available In the last two decades, the industry has deployed endlessly the rhetoric of the “digital threat” in order to demand harsher measures against digital piracy. Recently, the “digital threat” discourse called for enhanced liability of online intermediaries, especially those whose platforms may be used to infringe copyright. This short paper shows that the “digital threat” discourse is based on shaky grounds. Two related arguments might run against this approach. First, market conditions might incentivise piracy. Additionally, there are raising doubts over the argument that piracy is a threat to creativity, especially in the digital environment. Overall, it may be hard to find a factual justification for policy decisions based on the “digital threat” discourse. In fact, digital technology seems not to have negatively affected the creation of new works. In contrast, an observation of the literature and quantitative analysis on point may suggest that digital piracy can be an opportunity for the cultural market. Finally, piracy may function as an innovation policy by forcing market players to innovate in response to a consumer demand that widespread piracy highlights.

  12. Glucose and Intermediary Metabolism and Astrocyte-Neuron Interactions Following Neonatal Hypoxia-Ischemia in Rat.

    Science.gov (United States)

    Brekke, Eva; Berger, Hester Rijkje; Widerøe, Marius; Sonnewald, Ursula; Morken, Tora Sund

    2017-01-01

    Neonatal hypoxia-ischemia (HI) and the delayed injury cascade that follows involve excitotoxicity, oxidative stress and mitochondrial failure. The susceptibility to excitotoxicity of the neonatal brain may be related to the capacity of astrocytes for glutamate uptake. Furthermore, the neonatal brain is vulnerable to oxidative stress, and the pentose phosphate pathway (PPP) may be of particular importance for limiting this kind of injury. Also, in the neonatal brain, neurons depend upon de novo synthesis of neurotransmitters via pyruvate carboxylase in astrocytes to increase neurotransmitter pools during normal brain development. Several recent publications describing intermediary brain metabolism following neonatal HI have yielded interesting results: (1) Following HI there is a prolonged depression of mitochondrial metabolism in agreement with emerging evidence of mitochondria as vulnerable targets in the delayed injury cascade. (2) Astrocytes, like neurons, are metabolically impaired following HI, and the degree of astrocytic malfunction may be an indicator of the outcome following hypoxic and hypoxic-ischemic brain injury. (3) Glutamate transfer from neurons to astrocytes is not increased following neonatal HI, which may imply that astrocytes fail to upregulate glutamate uptake in response to the massive glutamate release during HI, thus contributing to excitotoxicity. (4) In the neonatal brain, the activity of the PPP is reduced following HI, which may add to the susceptibility of the neonatal brain to oxidative stress. The present review aims to discuss the metabolic temporal alterations observed in the neonatal brain following HI.

  13. Corrosion inhibition in sputter-deposited thin-film systems using an intermediary layer of palladium

    Energy Technology Data Exchange (ETDEWEB)

    Sharp, D.J.

    1979-03-01

    Accelerated and long term corrosion data are presented for the Ti--Ag and Cr--Au thin film metallization systems deposited by sputter deposition. The Ti--Ag conductor system is used as an electrode for high intensity silicon solar cells, and it has been found that an intermediate layer of 1500 A of palladium greatly improves the environmental stability of the metallization. The Cr--Au system has been used as an electrical circuit pattern, and thin films of palladium (100--300 A) have been incorporated to improve storage, processing, and service stability. A 100 A palladium intermediary did not affect the etch patterning of the Cr--Au metallization. It is observed that the introduction of palladium modifies the anodic potential of the active metal producing a passive oxide when exposed to an electrolytic environment. It is proposed that this modified oxide, at exposed pinhole sites, is responsible for the increased corrosion resistance when palladium is present as an intermediate layer for either the Ti--Ag or Cr--Au metallization systems.

  14. Performance Evaluation of the Intermediary Channels of Life Insurance Industry in India

    Directory of Open Access Journals (Sweden)

    Sumninder Kaur BAWA

    2016-05-01

    Full Text Available The present study aims to canvass the performance of intermediary channels in Indian Life Insurance Industry viz. individual agents, corporate agents, bancassurance, brokers and direct selling. The conduct of performance has been deliberated in context of business premium collected and number of policies issued by various channels through Two-Way ANOVA. The data has been figured out over the period of seven years, i.e. from 2006- 07 to 2012-13. The findings demonstrate that in the context of premium as well as policy, there is difference in mean scores for various categories of channels, but no difference has been found with respect to time period. Besides the study also measures the augmentation in their performance, through compound annual growth rate (CAGR by using the log linear regression model which reveals that individual agent is the foremost performing channel in terms of generating business. But sustaining efficacy of every channel has become one of the confronting issues for insurance domain.

  15. Social features of online networks: the strength of intermediary ties in online social media.

    Directory of Open Access Journals (Sweden)

    Przemyslaw A Grabowicz

    Full Text Available An increasing fraction of today's social interactions occur using online social media as communication channels. Recent worldwide events, such as social movements in Spain or revolts in the Middle East, highlight their capacity to boost people's coordination. Online networks display in general a rich internal structure where users can choose among different types and intensity of interactions. Despite this, there are still open questions regarding the social value of online interactions. For example, the existence of users with millions of online friends sheds doubts on the relevance of these relations. In this work, we focus on Twitter, one of the most popular online social networks, and find that the network formed by the basic type of connections is organized in groups. The activity of the users conforms to the landscape determined by such groups. Furthermore, Twitter's distinction between different types of interactions allows us to establish a parallelism between online and offline social networks: personal interactions are more likely to occur on internal links to the groups (the weakness of strong ties; events transmitting new information go preferentially through links connecting different groups (the strength of weak ties or even more through links connecting to users belonging to several groups that act as brokers (the strength of intermediary ties.

  16. Mitochondrial uncoupling and the reprogramming of intermediary metabolism in leukemia cells

    Directory of Open Access Journals (Sweden)

    Juliana eVélez

    2013-04-01

    Full Text Available Nearly 60 years ago Otto Warburg proposed, in a seminal publication, that an irreparable defect in the oxidative capacity of normal cells supported the switch to glycolysis for energy generation and the appearance of the malignant phenotype (Warburg, 1956. Curiously, this phenotype was also observed by Warburg in embryonic tissues, and recent research demonstrated that normal stem cells may indeed rely on aerobic glycolysis – fermenting pyruvate to lactate in the presence of ample oxygen - rather than on the complete oxidation of pyruvate in the Krebs cycle - to generate cellular energy (Folmes et al., 2012. However, it remains to be determined whether this phenotype is causative for neoplastic development, or rather the result of malignant transformation. In addition, in light of mounting evidence demonstrating that cancer cells can carry out electron transport and oxidative phosphorylation, although in some cases predominantly using electrons from non-glucose carbon sources (Bloch-Frankenthal et al., 1965, Warburg´s hypothesis needs to be revisited. Lastly, recent evidence suggests that the leukemia bone marrow microenvironment promotes the Warburg phenotype adding another layer of complexity to the study of metabolism in hematological malignancies. In this review we will discuss some of the evidence for alterations in the intermediary metabolism of leukemia cells and present evidence for a concept put forth decades ago by lipid biochemist Feodor Lynen, and acknowledged by Warburg himself, that cancer cell mitochondria uncouple ATP synthesis from electron transport and therefore depend on glycolysis to meet their energy demands (Lynen, 1951;Warburg, 1956.

  17. The Cardiomyocyte RNA-Binding Proteome: Links to Intermediary Metabolism and Heart Disease

    Directory of Open Access Journals (Sweden)

    Yalin Liao

    2016-08-01

    Full Text Available RNA functions through the dynamic formation of complexes with RNA-binding proteins (RBPs in all clades of life. We determined the RBP repertoire of beating cardiomyocytic HL-1 cells by jointly employing two in vivo proteomic methods, mRNA interactome capture and RBDmap. Together, these yielded 1,148 RBPs, 391 of which are shared with all other available mammalian RBP repertoires, while 393 are thus far unique to cardiomyocytes. RBDmap further identified 568 regions of RNA contact within 368 RBPs. The cardiomyocyte mRNA interactome composition reflects their unique biology. Proteins with roles in cardiovascular physiology or disease, mitochondrial function, and intermediary metabolism are all highly represented. Notably, we identified 73 metabolic enzymes as RBPs. RNA-enzyme contacts frequently involve Rossmann fold domains with examples in evidence of both, mutual exclusivity of, or compatibility between RNA binding and enzymatic function. Our findings raise the prospect of previously hidden RNA-mediated regulatory interactions among cardiomyocyte gene expression, physiology, and metabolism.

  18. Gain of harmonic generation in high gain free electron laser

    Institute of Scientific and Technical Information of China (English)

    DENG Hai-Xiao; DAI Zhi-Min

    2008-01-01

    In a planar undulator employed free electron laser(FEL),each harmonic radiation starts from linear amplification and ends with nonlinear harmonic interactions of the lower nonlinear harmonics and the fundamental radiation.In this paper,we investigate the harmonic generation based on the dispersion relation driven from the coupled Maxwell-Vlasov equations,taking into account the effects due to energy spread,emittance,betatron oscillation of electron beam as well as diffraction guiding of the radiation field.A 3D universal scaling function for gain of the linear harmonic generation and a 1D universal scaling function for gain of the nonlinear harmonic generation are presented,which promise rapid computation in FEL design and optimization.The analytical approaches have been validated by 3D simulation results in large range.

  19. A Novel Technique to Measure Gain Spectrum for Fabry-Pérot Semiconductor Lasers

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    A novel gain measurement technique based on the integration of the measured amplified spontaneous emission spectrum multiplying a phase function over one longitudinal mode interval is proposed for Fabry-Perot semiconductor lasers.

  20. ASSESSMENT OF THE CONTROLLABILITY OF CONDENSIBLE EMISSIONS

    Science.gov (United States)

    The report gives results of a study to gain insights into the condensible emissions area from an air toxics perspective, with emphasis on controllability and chemical composition of these emissions. he study compiled existing data on condensible emissions; determined the chemical...

  1. Cassegrain-Antenna Gain Improvement

    Science.gov (United States)

    Galindo, V.; Cha, A. G.; Mittra, R.

    1986-01-01

    Modified antenna feed with dual-shaped subreflectors yields 10-to20-percent improvement in efficiency of existing large-aperture paraboloidal or Cassegrainian antennas. Such offset dual-shaped subreflector (DSS) feed brings gain of existing paraboloid or Cassegrain antennas up to that of reflector antennas of more recent design at cost considerably lower than for reshaping existing reflecting surfaces. Mathematical procedures developed for synthesizing nearly optimum shapes for DSS elements of new feeds.

  2. Emission Trading

    OpenAIRE

    2009-01-01

    The work concerns Emission Trading Scheme from perspektive of taxes and accounting. I should show problems with emission trading. The work concerns practical example of trading with emission allowance.

  3. Phosphorylated form of adrenocorticotropin and corticotropin-like intermediary lobe peptide in human tumors

    Energy Technology Data Exchange (ETDEWEB)

    Massias, J.F.; Hardouin, S.; Vieau, D.; Lenne, F.; Bertagna, X. (Univ Rene Descartes, Paris (France))

    1994-10-01

    Many peptides contribute to the heterogeneity of immunoreactive adrenocorticotropin (ACTH) in man. The use of a radioimmunoassay (RIA) specifically directed against the C-terminal end of ACTH allowed the precise study of the following four peptides: ACTH itself, corticotropin-like intermediary lobe peptide (CLIP) or ACTH and their phosphorylated forms on SeR[sup 31]. The authors have set up a high-performance liquid chromatography system that separates these four molecules in a single run, to establish their relative distributions in tumors responsible for Cushing's disease or for the ectopic ACTH syndrome, and to evaluate the possible interference of phospho-Ser[sup 31] on various RIA or immuno-radiometric assay (IRMA) recognition systems for ACTH. In this system, alkaline phosphatase treatment shifted the retention time of the phosphorylated peptides to that of their non-phosphorylated counterparts. In three tumors responsible for the ectopic ACTH syndrome, CLIP peptides were predominant in two and phosphorylated molecules represented between 22% and 50% of immuno-reactive materials. In five pituitary tumors responsible for Cushing's disease, ACTH peptides were predominant and the phosphorylated molecules varied between 35% and 75% in four of them. In the same tumor the ratios of phosphorylated to non-phosphorylated CLIP or ACTH were identical. The presence of phospho-Ser[sup 31] did not affect the recognition ability of two mid-ACTH and two C-terminal ACTH RIA's, nor of the ACTH IRMA. 15 refs., 5 figs., 2 tabs.

  4. Influence of intermediary filling material on microleakage of intracoronally bleached and restored teeth

    Directory of Open Access Journals (Sweden)

    Maryam Khoroushi

    2009-01-01

    Full Text Available Background: Failure of composite restorations in terms of microleakage after intracoronal bleaching has been reported. The purpose of this study was to assess in vitro effect of sodium ascorbate and calcium hydroxide as intermediary filling materials to repair the microleakage associated with adhe-sive restoration following intracoronal bleaching. Methods: Sixty endodontically-treated incisors with access cavities extended to the cementoenamel junction in gingival margin were randomly divided into five equal groups. In group 1, cavities were restored by applying Single Bond and Z100 composite resin. In groups 2-5, 35% hydrogen peroxide gel was placed into the pulp chamber and sealed for 5 days. In group 2, teeth were then restored as in group 1. In groups 3 and 4, 10% sodium ascorbate gel and calcium hydroxide paste were applied in the pulp chamber for 40 hours, removed, rinsed and then, restored. In group 5, the cavities were incu-bated for 7 days and then, restored. Samples were thermocycled, immersed in basic fuschin, and sec-tioned. Dye penetration was scored using a stereomicroscope. Data were analyzed using Kruskal- Wallis and Mann-Whitney U tests (α = 0.05. Results: There was no significant difference in enamel margins (P = 0.163. In dentinal margins (P = 0.003, groups 1, 3 and 5 exhibited similar leakage patterns, each one of groups 1, 3 and 5 had sig-nificant differences with each one of groups 2 and 4. Conclusion: Intracoronal bleaching using 35% H2O2 gel increases the microleakage in dentinal margins. Application of the antioxidant agent or a seven-day delay following bleaching may improve the marginal integrity. Applying calcium hydroxide might jeopardize dentinal sealing.

  5. The magnetopause as an intermediary between interplanetary structures and the Earth's inner magnetosphere

    Science.gov (United States)

    Hwang, K.; Sibeck, D. G.; Fok, M. H.; Zheng, Y.; Glocer, A.; Mitchell, D. G.

    2013-12-01

    Observational studies using data from multipoint spacecraft combined with global modeling of the Earth's magnetosphere are presented to understand the magnetopause as an intermediary between interplanetary structures and the inner magnetosphere in response to a variety of solar-wind structures, such as Coronal Mass Ejections (CMEs), Corotating Interaction Regions (CIRs), interplanetary shocks, and pressure pulses. The importance of the magnetopause in the solar wind-inner magnetosphere coupling arises not only from its global motion, which determines the location of the magnetopause relative to the drift paths of outer radiation-belt particles, but also from physical processes occurring at the magnetopause boundary layer. Common physical processes occurring at the magnetopause boundary layer include Kelvin-Helmholtz waves and newly-identified velocity fluctuations, which both provide multiple channels to increase, decrease, or modulate inner-magnetospheric particle density/energy fluxes. We have surveyed the data sets, finding a number of events in which THEMIS observed magnetopause boundary waves while the Van Allen Probes observed flux enhancements in response to various solar-wind structures. Ultra-Low-Frequency (ULF) waves are often excited by, or enhanced, during these boundary fluctuations. Simultaneous intensifications and/or modulations in the energetic radiation belt and ring current populations are common. Amongst these events, we present categorized case studies in which inner-magnetospheric fluxes are regulated by different solar wind-magnetopause couplings. These results provide evidence that the energy from the interplanetary structures is transferred into the inner magnetosphere via magnetopause dynamics. We use measurements from multiple spacecraft including the Van Allen Probes and the THEMIS and global MHD simulations to track down the mechanisms by which this transport is implemented.

  6. GAIN Technology Workshops Summary Report

    Energy Technology Data Exchange (ETDEWEB)

    Braase, Lori Ann [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-08-01

    National and global demand for nuclear energy is increasing and United States (U.S.) global leadership is eroding. There is a sense of urgency with respect to the deployment of the innovative nuclear energy technologies. The Gateway for Accelerated Innovation in Nuclear (GAIN) initiative is based on the simultaneous achievement of three strategic goals. The first is maintaining global technology leadership within the U.S. Department of Energy (DOE). The second is enabling global industrial leadership for nuclear vendors and suppliers. The third is focused on utility optimization of nuclear energy within the clean energy portfolio. An effective public-private partnership is required to achieve these goals. DOEs recognizes the recent sense of urgency new developers and investors have in getting their concepts to market. They know that time to market for nuclear technology takes too long and the facilities needed to conduct the necessary research, development and demonstration (RD&D) activities are very expensive to develop and maintain. Early technologies, in the lower technology readiness levels (TRL) need materials testing, analysis, modeling, code development, etc., most of which currently exists in the DOE national laboratory system. However, mature technologies typically need large component testing and demonstration facilities, which are expensive and long-lead efforts. By understanding the needs of advanced nuclear technology developers, GAIN will connect DOE national laboratory capabilities (e.g., facilities, expertise, materials, and data) with industry RD&D needs. In addition, GAIN is working with the Nuclear Regulatory Commission (NRC) to streamline processes and increase understanding of the licensing requirements for advanced reactors.

  7. Commutated automatic gain control system

    Science.gov (United States)

    Yost, S. R.

    1982-01-01

    The commutated automatic gain control (AGC) system was designed and built for the prototype Loran-C receiver is discussed. The current version of the prototype receiver, the Mini L-80, was tested initially in 1980. The receiver uses a super jolt microcomputer to control a memory aided phase loop (MAPLL). The microcomputer also controls the input/output, latitude/longitude conversion, and the recently added AGC system. The AGC control adjusts the level of each station signal, such that the early portion of each envelope rise is about at the same amplitude in the receiver envelope detector.

  8. A gain-coefficient switched Alexandrite laser

    NARCIS (Netherlands)

    Lee, Chris J.; Slot, van der Peter J.M.; Boller, Klaus-J.

    2013-01-01

    We report on a gain-coefficient switched Alexandrite laser. An electro-optic modulator is used to switch between high and low gain states by making use of the polarization dependent gain of Alexandrite. In gain-coefficient switched mode, the laser produces 85 ns pulses with a pulse energy of 240 mJ

  9. A gain-coefficient switched Alexandrite laser

    CERN Document Server

    Lee, Chris J; Boller, Klaus-J

    2012-01-01

    We report on a gain-coefficient switched Alexandrite laser. An electro-optic modulator is used to switch between high and low gain states by making use of the polarization dependent gain of Alexandrite. In gain-coefficient switched mode, the laser produces 85 ns pulses with a pulse energy of 240 mJ at a repetition rate of 5 Hz.

  10. Tumor cell metabolism: the marriage of molecular genetics and proteomics with cellular intermediary metabolism; proceed with caution!

    Directory of Open Access Journals (Sweden)

    Franklin Renty B

    2006-11-01

    Full Text Available Abstract Metabolic transformations of malignant cells are essential to the development and progression of all cancers. The understanding of the pathogenesis and progression of cancer requires the establishment of the altered genetic/metabolic factors that are essential to the development, growth, and proliferation of the malignant cells. Recognition of this important relationship has resulted in a resurgence of interest in the intermediary metabolism of tumor cells. The role of molecular genetics and proteomics and the application of molecular technology in assessing altered cellular metabolism has become a major area of biomedical research. The contemporary generation of biomedical scientists is exceptionally well trained in all areas of molecular biology and molecular technology, which are now important tools to be applied to the regulation of cellular intermediary metabolism. Simultaneously, the didactic and methodological training associated with the principles and operation of metabolic pathways, enzymology, cellular enzyme activity, and associated biochemical implications has been diminished and often eliminated from the pre- and post-doctoral programs. Interpretations and conclusions of alterations in cellular enzyme activity and associated metabolic pathways based on genetic/proteomic changes can and will result in misrepresentation of important metabolic implications in malignancy and other diseases. It is essential that the genetic/proteomic studies be coupled to biochemical/metabolic cellular events to satisfy the axiom: "genetic transformations and proteomic alterations will have little relevancy to disease processes if the genetic/proteomic alterations are not manifested in altered and impaired cellular and metabolic function". The appropriate marriage of molecular genetics/proteomics with the regulation of cellular intermediary metabolism will provide new revelations and understanding of malignancy that could not be achieved in

  11. Detailed theoretical and experimental investigation of high-gain erbium-doped fiber amplifier

    DEFF Research Database (Denmark)

    Pedersen, Bo; Dybdal, Kristen; Dam-Hansen, Carsten

    1990-01-01

    A full-scale numerical model for the erbium-doped fiber amplifier has been developed that incorporates realistic index and erbium-concentration profiles as well as the spectral distribution of amplified spontaneous emission (ASE). The high accuracy of the model is demonstrated by comparison...... with a comprehensive set of data, including gain, ASE, and pump power, obtained for a well-characterized Er-Al-doped fiber. An absorption-to-emission cross-section ratio of 1.0 was measured at the gain peak. Pumping at 654 nm, the excited state absorption was observed to be insignificant. A high gain of 39.6 d...

  12. Information Gains from Cosmological Probes

    CERN Document Server

    Grandis, S; Refregier, A; Amara, A; Nicola, A

    2015-01-01

    In light of the growing number of cosmological observations, it is important to develop versatile tools to quantify the constraining power and consistency of cosmological probes. Originally motivated from information theory, we use the relative entropy to compute the information gained by Bayesian updates in units of bits. This measure quantifies both the improvement in precision and the 'surprise', i.e. the tension arising from shifts in central values. Our starting point is a WMAP9 prior which we update with observations of the distance ladder, supernovae (SNe), baryon acoustic oscillations (BAO), and weak lensing as well as the 2015 Planck release. We consider the parameters of the flat $\\Lambda$CDM concordance model and some of its extensions which include curvature and Dark Energy equation of state parameter $w$. We find that, relative to WMAP9 and within these model spaces, the probes that have provided the greatest gains are Planck (10 bits), followed by BAO surveys (5.1 bits) and SNe experiments (3.1 ...

  13. Fat metaplasia and backfill are key intermediaries in the development of sacroiliac joint ankylosis in patients with ankylosing spondylitis

    DEFF Research Database (Denmark)

    Maksymowych, Walter P; Wichuk, Stephanie; Chiowchanwisawakit, Praveena

    2014-01-01

    bone in the sacroiliac (SI) joints and may reflect resolution of inflammation and tissue repair at sites of erosions. The purpose of this study was to test our hypothesis that SI joint ankylosis develops following repair of erosions and that tissue characterized by fat metaplasia is a key intermediary...... step in this pathway. METHODS: We used the Spondyloarthritis Research Consortium of Canada (SPARCC) SI structural lesion score (SSS) method to assess fat metaplasia, erosions, backfill, and ankylosis on MRIs of the SI joints in 147 patients with AS monitored for 2 years. Univariate and multivariate...

  14. Estimating the potential gains from mergers

    DEFF Research Database (Denmark)

    Bogetoft, Peter; Wang, Dexiang

    2005-01-01

    We introduce simple production economic models to estimate the potential gains from mergers. We decompose the gains into technical ef¿ciency, size (scale) and harmony (mix) gains, and we discuss alternative ways to capture these gains. We propose to approximate the production processes using...... the non-parametric. Data Envelopment Analysis (DEA) approach, and we use the resulting operational approach to estimate the potential gains from merging agricultural extension of¿ces in Denmark....

  15. Analysis on the value about the existence of economy intermediary organization%经济型中介组织存在的价值分析

    Institute of Scientific and Technical Information of China (English)

    李华

    2009-01-01

    通过运用文献分析等方法给出了经济中介主要职能的理论解释,概述了政府管理市场和市场管理市场的政策建议.%A proper social mediating system is required for a modern market economy with complete system, com-plete function and quick information. With unique status, intermediary organization has important functions which the government and enterprise cant display. As bridge and link of microscopic economic subject regulating macro-scopic government, intermediary organization promotes the market economy in healthy, orderly and standard situa-tion. The overall goal is to provide theory explanation about main function of economy intermediary organization,outline some policy suggestions on government management of market and market management by market.

  16. Sudden gains in behavioural activation for depression.

    Science.gov (United States)

    Masterson, Ciara; Ekers, David; Gilbody, Simon; Richards, David; Toner-Clewes, Benjamin; McMillan, Dean

    2014-09-01

    Sudden gains have been linked to improved outcomes in cognitive behaviour therapy for depression. The relationship between sudden gains and outcome is less clear in other treatment modalities, including interpersonal psychotherapy and supportive expressive therapy, which may indicate different mechanisms of change between treatment modalities. The current study examined sudden gains in adults meeting diagnostic criteria for depression (N = 40) offered up to 12 sessions of behavioural activation treatment. Sudden gains were found in 42.5% of the sample. Sudden gains occurred early (median pre-gain session 2) and were related to outcome: those who experienced a sudden gain had significantly lower post-treatment scores on the PHQ-9. Furthermore, the proportion meeting the reliable and clinically significant change criteria at end of treatment was higher in the sudden gain group. These findings highlight the importance of understanding the mechanisms by which sudden gains relate to therapy outcome in behavioural activation.

  17. Spectral gain profile of a multi-stack terahertz quantum cascade laser

    Energy Technology Data Exchange (ETDEWEB)

    Bachmann, D., E-mail: dominic.bachmann@tuwien.ac.at; Deutsch, C.; Krall, M.; Unterrainer, K.; Darmo, J. [Photonics Institute, Vienna University of Technology, Gußhausstraße 27-29, 1040 Vienna (Austria); Center for Micro- and Nanostructures, Vienna University of Technology, Floragasse 7, 1040 Vienna (Austria); Rösch, M.; Scalari, G.; Beck, M.; Faist, J. [Institute for Quantum Electronics, ETH Zürich, Auguste-Piccard-Hof 1, 8093 Zürich (Switzerland)

    2014-11-03

    The spectral gain of a multi-stack terahertz quantum cascade laser, composed of three active regions with emission frequencies centered at 2.3, 2.7, and 3.0 THz, is studied as a function of driving current and temperature using terahertz time-domain spectroscopy. The optical gain associated with the particular quantum cascade stacks clamps at different driving currents and saturates to different values. We attribute these observations to varying pumping efficiencies of the respective upper laser states and to frequency dependent optical losses. The multi-stack active region exhibits a spectral gain full width at half-maximum of 1.1 THz. Bandwidth and spectral position of the measured gain match with the broadband laser emission. As the laser action ceases with increasing operating temperature, the gain at the dominant lasing frequency of 2.65 THz degrades sharply.

  18. Medicare program: data, standards, and methodology used to establish fiscal year 1994 budgets for fiscal intermediaries and carriers--HCFA. Final notice.

    Science.gov (United States)

    1994-07-14

    This notice is published in accordance with sections 1816(c)(1) and 1842(c)(1) of the Social Security Act which require us to publish the final data, standards, and methodology used to establish budgets for Medicare intermediaries and carriers. In this notice, we respond to the comments received in response to our notice of October 5, 1993 and we announce the adoption of the proposed data, standards, and methodology that we used to establish the Medicare fiscal intermediary and carrier budgets for fiscal year (FY) 1994, beginning October 1, 1993, as final and without revision.

  19. Changes to Intermediary Metabolites in Sporadic and LRRK2 Parkinson’s Disease Demonstrated by Proton Magnetic Resonance Spectroscopy

    Directory of Open Access Journals (Sweden)

    Jan O. Aasly

    2015-01-01

    Full Text Available Background. Parkinson’s disease (PD remains a clinical diagnosis and biomarkers are needed to detect the disease as early as possible. Genetically determined PD provides an opportunity for studying metabolic differences in connection with disease development. Objectives. To study the levels of intermediary metabolites in cerebrospinal fluid (CSF from patients with PD, either of sporadic type or in carriers of the LRRK2 p.G2019S mutation. Methods. Results from patients with sporadic PD or LRRK2-PD were compared with asymptomatic LRRK2 mutation carriers and healthy control individuals. CSF was analysed by proton MR spectroscopy (1H-MRS giving reliable results for 16 intermediary metabolites. Partial least squares discriminant analysis (PLS-DA was applied to study group differences. Results. PLS-DA distinguished PD patients from healthy individuals based on the metabolites identified in CSF, with 2-hydroxybutyrate, glutamine, and dimethyl sulphone largely contributing to the separations. Conclusion. Speculatively, all three metabolites could alter concentration in response to metabolic changes connected with neurodegeneration; glutamine as a means of removing excess nitrogen from brain, dimethyl sulphone as an anti-inflammatory agent, and 2-hydroxybutyrate in connection with altered glutathione metabolism. Potentially, 1H-MRS is a promising tool for identifying novel biomarkers for PD.

  20. Effects of host plants on digestive enzymatic activities and some components involved in intermediary metabolism of Chrysodeixis chalcites (Lepidoptera: Noctuidae

    Directory of Open Access Journals (Sweden)

    M. Mardani-Talaee

    2014-12-01

    Full Text Available Chrysodeixis chalcites (Esper is a serious pest that causes devastating damages in infested areas to many fruits, vegetables, ornamental crops and weeds. In the current study, effects of three host plants including lemon balm (Melissa officinalis L.; corn (Zea mays L. and dill (Anethum graveolens L. were determined on digestive enzyme activities and intermediary metabolism of C. chalcites larvae. The highest activities of α-amylase, glucosidases and specific proteases were observed in the larvae fed on dill. Our results showed that C. chalcites larvae had the highest TAG-lipase activity on corn in comparison with other host plants. Significant differences were found among enzymatic activities of acid (ACP and alkaline phosphatases, aspartate aminotransferases and lactate dehydrogenase (LDH in the haemolymph of C. chalcites larvae reared on lemon balm, corn and dill, respectively, although activity of alanine aminotransferase showed no statistically significant differences among different host plants. The enzymatic activity of ACP significantly decreased on dill in comparison with lemon balm and corn. The activity of LDH significantly increased on dill compared with other host plants. These results revealed that dill (A. graveolens is the most appropriate host plant for larvae of C. chalcites as evidenced by the highest digestive enzyme activities and intermediary metabolism.

  1. [Impact of water resource installations on the distribution of schistosomiasis and its intermediary hosts in Burkina Faso].

    Science.gov (United States)

    Poda, Jean-Noël; Sondo, Blaise; Parent, Gérard

    2003-01-01

    Dams generally are a favourable biotope for the molluscs acting as intermediary hosts to schistosomiasis. The importance of the schistosomiasis endemic which follows depends on the interactions taking place between the parasites and their definitive (humans) and intermediary hosts. A preliminary sound knowledge of the prevailing epidemiological situations is therefore necessary to define an efficient programme to fight these infections. The extension of schistosomiasis following the installation of water resource facilities is significative of the part played by these hosts. In the hydroagricultural complex of Sourou, the prevalence of urinary schistosomiasis increased from 19% in 1954 to more than 70% in 1998-1999 in Guiédougou, the most ancient site. As to digestive schistosomiasis, almost unheard of until 1987, its prevalence ranged from 8% to 69% in 1998 in the villages located alongside the areas thus equipped. In the Kou Valley, the prevalence went up from 14% in 1957 to 80% in 1974 for urinary schistosomiasis and from 1.3% to 45% for intestinal schistosomiasis. The same tendencies are likely to appear in the hydraulic installations of Bagré, Ziga, and Kompienga. Dams thus constitute amplifying factors for the proliferation of species and for parasite-host interactions. All the actors (developers, populations and scientists) are faced with the challenge of finding a mean to control the development of schistosomiasis infections which are likely to seriously lessen the benefits expected from these hydraulic installations.

  2. State of the art. Four easy pieces: interconnections between tissue injury, intermediary metabolism, autoimmunity, and chronic degeneration.

    Science.gov (United States)

    Steinman, Lawrence

    2006-08-01

    Four questions are posed: (1) Can tissue damage itself provoke autoimmunity? (2) Can genetic mutations of key structures produce tissue pathology and thus provoke autoimmunity? (3) Can acute immune damage produce tissue degeneration without further hallmarks of an immune response? (4) Can intermediary metabolism modulate immune damage to tissues? Four answers are given: (1) Tissue injury itself may lead to autoimmunity. Both innate and adaptive immunity may arise as a response to tissue injury, and the immune attack can further damage tissue. (2) Genetic mutations can lead to an immune response indistinguishable from autoimmunity, exemplified from Duchenne's Muscular Dystrophy and X-linked adrenoleukodystrophy. (3) Chronic immune damage may lead to tissue degeneration, with or without further hallmarks of an immune response. Variations on this theme, including inverse scenarios, are also possible: Inborn errors of metabolism may lead to tissue damage that may provoke an adaptive and or innate immune response. The immune response might further damage tissue. (4) Finally, perturbations of intermediary metabolism may modulate the immune response, controlling the extent of immune-mediated damage. Examples are taken from perturbations in the cholesterol pathway that influence the characteristics of the immune response, and with tryptophan metabolites that modulate autoimmunity and graft rejection. Inflammatory, degenerative, and autoimmune neurological disease will be discussed in terms of their implications for pathogenic mechanisms underlying chronic obstructive pulmonary disease.

  3. The cyanobacterial amino acid β-N-methylamino-l-alanine perturbs the intermediary metabolism in neonatal rats.

    Science.gov (United States)

    Engskog, Mikael K R; Karlsson, Oskar; Haglöf, Jakob; Elmsjö, Albert; Brittebo, Eva; Arvidsson, Torbjörn; Pettersson, Curt

    2013-10-01

    The neurotoxic amino acid β-N-methylamino-l-alanine (BMAA) is produced by most cyanobacteria. BMAA is considered as a potential health threat because of its putative role in neurodegenerative diseases. We have previously observed cognitive disturbances and morphological brain changes in adult rodents exposed to BMAA during the development. The aim of this study was to characterize changes of major intermediary metabolites in serum following neonatal exposure to BMAA using a non-targeted metabolomic approach. NMR spectroscopy was used to obtain serum metabolic profiles from neonatal rats exposed to BMAA (40, 150, 460mg/kg) or vehicle on postnatal days 9-10. Multivariate data analysis of binned NMR data indicated metabolic pattern differences between the different treatment groups. In particular five metabolites, d-glucose, lactate, 3-hydroxybutyrate, creatine and acetate, were changed in serum of BMAA-treated neonatal rats. These metabolites are associated with changes in energy metabolism and amino acid metabolism. Further statistical analysis disclosed that all the identified serum metabolites in the lowest dose group were significantly (pmodel used in this study is so far the only animal model that displays significant biochemical and behavioral effects after a low short-term dose of BMAA. The demonstrated perturbation of intermediary metabolism may contribute to BMAA-induced developmental changes that result in long-term effects on adult brain function.

  4. What do we need from intermediaries for technology transfer to China?

    DEFF Research Database (Denmark)

    Li-Ying, Jason

    2012-01-01

    Cross-national technology transfer has been one of the most important vehicles by which firms in developed countries exploit the value of their technological innovations, and firms in developing countries gain access to technological and organizational knowledge from developed economies. To facil...

  5. Factors influencing weight gain after renal transplantation.

    Science.gov (United States)

    Johnson, C P; Gallagher-Lepak, S; Zhu, Y R; Porth, C; Kelber, S; Roza, A M; Adams, M B

    1993-10-01

    Weight gain following renal transplantation occurs frequently but has not been investigated quantitatively. A retrospective chart review of 115 adult renal transplant recipients was used to describe patterns of weight gain during the first 5 years after transplantation. Only 23 subjects (21%) were overweight before their transplant. Sixty-six subjects (57%) experienced a weight gain of greater than or equal to 10%, and 49 subjects (43%) were overweight according to Metropolitan relative weight criteria at 1 year after transplantation. There was an inverse correlation between advancing age and weight gain, with the youngest patients (18-29 years) having a 13.3% weight gain and the oldest patients (age greater than 50 years) having the lowest gain of 8.3% at 1 year (P = 0.047). Black recipients experienced a greater weight gain than whites during the first posttransplant year (14.6% vs. 9.0%; P = 0.043), and maintained or increased this difference over the 5-year period. Men and women experienced comparable weight gain during the first year (9.5% vs. 12.1%), but women continued to gain weight throughout the 5-year study (21.0% total weight gain). The men remained stable after the first year (10.8% total weight gain). Recipients who experienced at least a 10% weight gain also increased their serum cholesterol (mean 261 vs. 219) and triglyceride (mean 277 vs. 159) levels significantly, whereas those without weight gain did not. Weight gain did not correlate with cumulative steroid dose, donor source (living-related versus cadaver), rejection history, pre-existing obesity, the number of months on dialysis before transplantation, or posttransplant renal function. Posttransplant weight gain is related mainly to demographic factors, not to treatment factors associated with the transplant. The average weight gain during the first year after renal transplantation is approximately 10%. This increased weight, coupled with changes in lipid metabolism, may be significant in

  6. Emissions Trading

    NARCIS (Netherlands)

    Woerdman, Edwin; Backhaus, Juergen

    2014-01-01

    Emissions trading is a market-based instrument to achieve environmental targets in a cost-effective way by allowing legal entities to buy and sell emission rights. The current international dissemination and intended linking of emissions trading schemes underlines the growing relevance of this

  7. Emissions Trading

    NARCIS (Netherlands)

    Woerdman, Edwin; Backhaus, Juergen

    2014-01-01

    Emissions trading is a market-based instrument to achieve environmental targets in a cost-effective way by allowing legal entities to buy and sell emission rights. The current international dissemination and intended linking of emissions trading schemes underlines the growing relevance of this instr

  8. AN OVERVIEW OF THE DEVELOPMENT OF LOW GAIN FEEDBACK AND LOW-AND-HIGH GAIN FEEDBACK

    Institute of Scientific and Technical Information of China (English)

    Zongli LIN

    2009-01-01

    Low gain feedback refers to certain families of stabilizing state feedback gains that are parameterized in a scalar and go to zero as the scalar decreases to zero. Low gain feedback was initially proposed to achieve semi-global stabilization of linear systems subject to input saturation. It was then combined with high gain feedback in different ways for solving various control problems. The resulting feedback laws are referred to as low-and-high gain feedback. Since the introduction of low gain feedback in the context of semi-global stabilization of linear systems subject to input saturation,there has been effort to develop alternative methods for low gain design, to characterize key features of low gain feedback, and to explore new applications of the low gain and low-and-high gain feedback.This paper reviews the developments in low gain and low-and-high gain feedback designs.

  9. The Flynn effect in Korea: Large gains

    NARCIS (Netherlands)

    te Nijenhuis, J.; Cho, S.H.; Murphy, R.; Lee, K.H.

    2012-01-01

    Secular gains in IQ test scores have been reported for many Western countries. This is the first study of secular IQ gains in South Korea, using various datasets. The first question is what the size of the Flynn effect in South Korea is. The gains per decade are 7.7 points for persons born between 1

  10. The Flynn effect in Korea: Large gains

    NARCIS (Netherlands)

    te Nijenhuis, J.; Cho, S.H.; Murphy, R.; Lee, K.H.

    2012-01-01

    Secular gains in IQ test scores have been reported for many Western countries. This is the first study of secular IQ gains in South Korea, using various datasets. The first question is what the size of the Flynn effect in South Korea is. The gains per decade are 7.7 points for persons born between

  11. Gain scheduling using the Youla parameterization

    DEFF Research Database (Denmark)

    Niemann, Hans Henrik; Stoustrup, Jakob

    1999-01-01

    Gain scheduling controllers are considered in this paper. The gain scheduling problem where the scheduling parameter vector cannot be measured directly, but needs to be estimated is considered. An estimation of the scheduling vector has been derived by using the Youla parameterization. The use...... in connection with H_inf gain scheduling controllers....

  12. Determination of optimal gains for constrained controllers

    Energy Technology Data Exchange (ETDEWEB)

    Kwan, C.M.; Mestha, L.K.

    1993-08-01

    In this report, we consider the determination of optimal gains, with respect to a certain performance index, for state feedback controllers where some elements in the gain matrix are constrained to be zero. Two iterative schemes for systematically finding the constrained gain matrix are presented. An example is included to demonstrate the procedures.

  13. Carbon Emissions from air-Conditioning

    OpenAIRE

    Rajesh Kumar

    2013-01-01

    This paper explores electricity consumption and carbon emissions associated with air-conditioning. The total heat load of a room fitted with air conditioner of 1.5 ton capacity has been calculated by calculating conduction and ventilation losses. Solar heat gain and internal gain were taken as the other two parameters for the total heat calculation.

  14. Carbon Emissions from air-Conditioning

    Directory of Open Access Journals (Sweden)

    Rajesh Kumar

    2013-01-01

    Full Text Available This paper explores electricity consumption and carbon emissions associated with air-conditioning. The total heat load of a room fitted with air conditioner of 1.5 ton capacity has been calculated by calculating conduction and ventilation losses. Solar heat gain and internal gain were taken as the other two parameters for the total heat calculation.

  15. Emission Facilities - Air Emission Plants

    Data.gov (United States)

    NSGIC Education | GIS Inventory — Represents the Primary Facility type Air Emission Plant (AEP) point features. Air Emissions Plant is a DEP primary facility type related to the Air Quality Program....

  16. Emission Facilities - Air Emission Plants

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Represents the Primary Facility type Air Emission Plant (AEP) point features. Air Emissions Plant is a DEP primary facility type related to the Air Quality Program....

  17. Emission inventory; Inventaire des emissions

    Energy Technology Data Exchange (ETDEWEB)

    Fontelle, J.P. [CITEPA, Centre Interprofessionnel Technique d`Etudes de la Pollution Atmospherique, 75 - Paris (France)

    1997-12-31

    Statistics on air pollutant (sulfur dioxide, nitrogen oxides and ammonium) emissions, acid equivalent emissions and their evolution since 1990 in the various countries of Europe and the USA, are presented. Emission data from the industrial, agricultural, transportation and power sectors are given, and comparisons are carried out between countries based on Gnp and population, pollution import/export fluxes and compliance to the previous emission reduction objectives

  18. Small signal gain in DPAL systems

    Science.gov (United States)

    Galbally-Kinney, Kristin L.; Maser, Daniel L.; Kessler, William J.; Rawlins, Wilson T.; Davis, Steven J.

    2011-03-01

    In this paper we describe a platform for small signal gain measurements for alkali atom laser systems based on the DPAL excitation method. We present initial results that clearly show the transition from absorption on the alkali atom D1 lines in Cs and Rb to optical transparency and positive gain. The achievement of optical gain is critically dependent upon alkali cell conditions and collision partners. We also present the first spatially resolved gain measurements in a DPAL system. The small signal gain methods described will be valuable tools for power scaling of these laser systems.

  19. Gain flattened distributed fiber raman amplifiers

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    An S band and a C band distributed fiber Raman amplifiers (DFRAs) with flattened gain and compensated dispersion have been studied and implemented with 1 427 nm and 1 455 nm mono-wavelength fiber Raman lasers as the pumped sources respectively. The gain of single-wave pumped S band and C band can reach 10 dB and 15 dB respectively. And a 50 nm gain flattened width was successfully obtained by using a chirp fiber Bragg grating (CFBG) gain flattened filter with gain ripple of 0.6 dB. The C band DFRA has been applied to CDMA wireless communication system successfully.

  20. Weight Gain, Obesity, and Psychotropic Prescribing

    Directory of Open Access Journals (Sweden)

    Nikhil Nihalani

    2011-01-01

    Full Text Available A majority of psychiatric medications are known to generate weight gain and ultimately obesity in some patients. There is much speculation about the prevalence of weight gain and the degree of weight gain during acute and longitudinal treatment with these agents. There is newer literature looking at the etiology of this weight gain and the potential treatments being used to alleviate this side effect. The authors undertook a comprehensive literature review in order to present epidemiology, etiology, and treatment options of weight gain associated with antipsychotics, mood stabilizers, and antidepressants.

  1. University-SME Collaboration and Open Innovation: Intellectual-Property Management Tools and the Roles of Intermediaries

    Directory of Open Access Journals (Sweden)

    Christian Eve-Levesque

    2013-03-01

    Full Text Available In 2009, the Conseil de la science et de la technologie du Québec (CST made 13 recommendations to the Government of Quebec in order to shift innovative actors towards open-innovation practices adapted to the province's context: diversified economic sectors, a majority of small and medium-sized enterprises (SMEs, public universities, etc. Among these recommendations are: i to set up flexible mechanisms to promote research collaboration between public-private sectors such as universities and SMEs, and ii to optimize intermediation bodies’ contribution to establish open-innovation practices. Furthermore, the lack of adequate understanding and tools for the management of intellectual property (IP was identified as a major inhibitor of open-innovation practices, to which actors should pay specific attention. In this article, we present results and recommendations from a field study focused on two groups of actors: i companies involved in collaborative innovation and ii intermediary agents enabling innovation and technology transfer. Our first goal was to shed some light on factors that facilitate open innovation through improved university-enterprise collaborations and, more importantly, that attempt to overcome the irritants related to IP management. Our second goal was to analyze the roles of diverse intermediaries in the fostering of successful collaborations between universities and SMEs. Our study yielded three findings: i SMEs do not care about understanding and improving their capabilities about IP and are not equipped with adequate tools and best practices for managing IP and for managing the overall collaborative mechanisms in general; ii this gap in preparation for open innovation is persistent, since even the intermediaries, whose role is to guide SMEs in university-enterprise collaborations, suffer themselves from the lack of appropriate IP transfer and sharing tools, and do not perceive the need to offer better support in this regard

  2. Analysis of emissions from prebunched electron beams

    Directory of Open Access Journals (Sweden)

    Jia Qika

    2017-07-01

    Full Text Available The emissions of the prebunched electron beam, including the coherent spontaneous emission and the self-amplified stimulated emission, are analyzed by using one-dimensional FEL theory. Neglecting the interaction of the electrons and the radiation field, the formula of the coherent spontaneous emission is given, the power of which is proportional to the square of the initial bunching factor and of the undulator length. For the general emission case of the prebunched electron beam, the evolution equation of the optical field is deducted. Then the analytical expression of the emission power is obtained for the resonant case; it is applicable to the regions from the low gain to the high gain. It is found that when the undulator length is shorter than four gain lengths, the emission is just the coherent spontaneous emission, and conversely, it is the self-amplified stimulated emission growing exponentially. For the nonresonant prebunched electron beam, the variations of the emission intensity with the detuning parameter for different interaction length are presented. The radiation field characters of the prebunched electron beam are discussed and compared with that of the seeded FEL amplifier.

  3. Analysis of emissions from prebunched electron beams

    Science.gov (United States)

    Jia, Qika

    2017-07-01

    The emissions of the prebunched electron beam, including the coherent spontaneous emission and the self-amplified stimulated emission, are analyzed by using one-dimensional FEL theory. Neglecting the interaction of the electrons and the radiation field, the formula of the coherent spontaneous emission is given, the power of which is proportional to the square of the initial bunching factor and of the undulator length. For the general emission case of the prebunched electron beam, the evolution equation of the optical field is deducted. Then the analytical expression of the emission power is obtained for the resonant case; it is applicable to the regions from the low gain to the high gain. It is found that when the undulator length is shorter than four gain lengths, the emission is just the coherent spontaneous emission, and conversely, it is the self-amplified stimulated emission growing exponentially. For the nonresonant prebunched electron beam, the variations of the emission intensity with the detuning parameter for different interaction length are presented. The radiation field characters of the prebunched electron beam are discussed and compared with that of the seeded FEL amplifier.

  4. The Utility of the Memorable Messages Framework as an Intermediary Evaluation Tool for Fruit and Vegetable Consumption in a Nutrition Education Program

    Science.gov (United States)

    Davis, LaShara A.; Morgan, Susan E.; Mobley, Amy R.

    2016-01-01

    Additional strategies to evaluate the impact of community nutrition education programs on low-income individuals are needed. The objective of this qualitative study was to examine the use of the Memorable Messages Framework as an intermediary nutrition education program evaluation tool to determine what fruit and vegetable messages were reported…

  5. Gain modulation by graphene plasmons in aperiodic lattice lasers

    Science.gov (United States)

    Chakraborty, S.; Marshall, O. P.; Folland, T. G.; Kim, Y.-J.; Grigorenko, A. N.; Novoselov, K. S.

    2016-01-01

    Two-dimensional graphene plasmon-based technologies will enable the development of fast, compact, and inexpensive active photonic elements because, unlike plasmons in other materials, graphene plasmons can be tuned via the doping level. Such tuning is harnessed within terahertz quantum cascade lasers to reversibly alter their emission. This is achieved in two key steps: first, by exciting graphene plasmons within an aperiodic lattice laser and, second, by engineering photon lifetimes, linking graphene’s Fermi energy with the round-trip gain. Modal gain and hence laser spectra are highly sensitive to the doping of an integrated, electrically controllable, graphene layer. Demonstration of the integrated graphene plasmon laser principle lays the foundation for a new generation of active, programmable plasmonic metamaterials with major implications across photonics, material sciences, and nanotechnology.

  6. Assessment of the controllability of condensible emissions. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Shareef, G.S.; Waddell, J.T.

    1990-10-01

    The report gives results of a study to gain insights into the condensible emissions area from an air toxics perspective, with emphasis on controllability and chemical composition of these emissions. The study: compiled existing data on condensible emissions; determined the chemical composition of condensible emissions, where possible; identified source categories that are major emitters of condensibles; evaluated the effectiveness of various control devices in reducing condensible emissions; and evaluated how the performance of currently available control technologies can be improved to better control condensible emissions. Two data bases were developed: the Condensibles Data Base contains 43 emission source categories; the Specialized Condensibles Data Base focuses on the chemical composition of condensible emissions.

  7. Transcriptional intermediary factor 1γ binds to the anaphase-promoting complex/cyclosome and promotes mitosis

    DEFF Research Database (Denmark)

    Sedgwick, G.G.; Townsend, K.; Martin, A.

    2013-01-01

    The anaphase-promoting complex/cyclosome (APC/C) is an ubiquitin ligase that functions during mitosis. Here we identify the transcriptional regulator, transcriptional intermediary factor 1γ, TIF1γ, as an APC/C-interacting protein that regulates APC/C function. TIF1γ is not a substrate for APC....../C-dependent ubiquitylation but instead, associates specifically with the APC/C holoenzyme and Cdc20 to affect APC/C activity and progression through mitosis. RNA interference studies indicate that TIF1γ knockdown results in a specific reduction in APC/C ubiquitin ligase activity, the stabilization of APC/C substrates......, and an increase in the time taken for cells to progress through mitosis from nuclear envelope breakdown to anaphase. TIF1γ knockdown cells are also characterized by the inappropriate presence of cyclin A at metaphase, and an increase in the number of cells that fail to undergo metaphase-to-anaphase transition...

  8. The End of Television—Again! How TV Is Still Influenced by Cultural Factors in the Age of Digital Intermediaries

    Directory of Open Access Journals (Sweden)

    Gunn Enli

    2016-07-01

    Full Text Available This article discusses the impact of convergence and digital intermediaries for television as a medium, industry and political and cultural institution. There is currently widespread debate about the future of television and the impact of technological and market changes. Our argument is that the answer to what is happening to television cannot be adequately addressed on a general level; local and contextual factors are still important, and so is the position and strategic response of existing television institutions in each national context. Based on analyses of political documents, statistics, audience research and media coverage, as well as secondary literature, the article explores the current situation for Norwegian television and point to four contexts that each plays a part in constraining and enabling existing television operators: the European context, the public service context, the welfare state context and the media ecosystem context.

  9. Metabolism alteration in follicular niche: The nexus among intermediary metabolism, mitochondrial function, and classic polycystic ovary syndrome.

    Science.gov (United States)

    Zhao, Hongcui; Zhao, Yue; Li, Tianjie; Li, Min; Li, Junsheng; Li, Rong; Liu, Ping; Yu, Yang; Qiao, Jie

    2015-09-01

    Classic polycystic ovary syndrome (PCOS) is a high-risk phenotype accompanied by increased risks of reproductive and metabolic abnormalities; however, the local metabolism characteristics of the ovaries and their effects on germ cell development are unclear. The present study used targeted metabolomics to detect alterations in the intermediate metabolites of follicular fluid from classic PCOS patients, and the results indicated that hyperandrogenism but not obesity induced the changed intermediate metabolites in classic PCOS patients. Regarding the direct contact, we identified mitochondrial function, redox potential, and oxidative stress in cumulus cells which were necessary to support oocyte growth before fertilization, and suggested dysfunction of mitochondria, imbalanced redox potential, and increased oxidative stress in cumulus cells of classic PCOS patients. Follicular fluid intermediary metabolic profiles provide signatures of classic PCOS ovary local metabolism and establish a close link with mitochondria dysfunction of cumulus cells, highlighting the role of metabolic signal and mitochondrial cross talk involved in the pathogenesis of classic PCOS.

  10. Neighborhood environment, physical activity, and quality of life in adults:Intermediary effects of personal and psychosocial factors

    Institute of Scientific and Technical Information of China (English)

    Eleni Theodoropoulou; Nektarios A.M.Stavrou; Konstantinos Karteroliotis

    2017-01-01

    Background:Studies have indicated that there is a positive and indirect relationship between physical activity (PA) and quality of life (QoL).The current study examined this relationship through a social cognitive model with consideration to the intermediary effects of exercise self-efficacy,and physical (PCS,physical component summary) and psychological (MCS,mental component summary) health.Additionally,this model was widened to include concepts from the ecological theory,and any causal associations among neighborhood environment,PA,and QoL.Methods:Six hundred and eighty-four physically active adults (39.16 ± 13.52 years,mean ± SD),living in Athens,Greece,completed a series of questionnaires measuring PA,QoL,exercise self-efficacy,PCS,MCS,neighborhood environment,and family and friend support for PA.The examined models were analyzed using structural equation modeling.Results:The social cognitive and ecological models proved to be of appropriate fit.Within the social cognitive model,PA positively affected QoL through the mediating effects of exercise self-efficacy,PCS,and MCS.With regards to the ecological model,neighborhood environment positively influenced QoL through the intermediary effects of family support for PA,exercise self-efficacy,PA,PCS,and MCS.Conclusion:Results indicated that the most important mediators in the examined models were exercise self-efficacy and health.Further,findings demonstrated the role of neighborhood environment in enhancing PA and QoL.Future studies should be carried out applying longitudinal data for a better understanding of these associations over time.

  11. Timing and amplitude jitter in a gain-switched multimode semiconductor laser

    Science.gov (United States)

    Wada, Kenji; Kitagawa, Naoaki; Matsukura, Satoru; Matsuyama, Tetsuya; Horinaka, Hiromichi

    2016-04-01

    The differences in timing jitter between a gain-switched single-mode semiconductor laser and a gain-switched multimode semiconductor laser are examined using rate equations that include Langevin noise. The timing jitter in a gain-switched multimode semiconductor laser is found to be effectively suppressed by a decrease in the coherence time of the amplified spontaneous emission (ASE) based on a broad bandwidth of multimode oscillation. Instead, fluctuations in the ASE cause amplitude jitter in the pulse components of the respective modes. A pulse train of gain-switched pulses from a multimode semiconductor laser with timing jitter is equivalently simulated by assuming a high spontaneous emission factor and a short coherence time of the ASE in the single-mode semiconductor laser rate equations.

  12. Influences of finite gain bandwidth on pulse propagation in parabolic fiber amplifiers with distributed gain profiles

    Institute of Scientific and Technical Information of China (English)

    Zhao Jia-Sheng; Li Pan; Chen Xiao-Dong; Feng Su-Juan; Mao Qing-He

    2012-01-01

    The evolutions of the pulses propagating in decreasing and increasing gain distributed fiber amplifiers with finite gain bandwidths are investigated by simulations with the nonlinear Schrodinger equation.The results show that the parabolic pulse propagations in both the decreasing and the increasing gain amplifiers are restricted by the finite gain bandwidth.For a given input pulse,by choosing a small initial gain coefficient and gain variation rate,the whole gain for the pulse amplification limited by the gain bandwidth may be higher,which is helpful for the enhancement of the output linearly chirped pulse energy.Compared to the decreasing gain distributed fiber amplifier,the increasing gain distributed amplifier may be more conducive to suppress the pulse spectral broadening and increase the critical amplifier length for achieving a larger output linearly chirped pulse energy.

  13. Gain Characteristics of Fiber Optical Parametric Amplifier

    Institute of Scientific and Technical Information of China (English)

    高明义; 姜淳; 胡卫生

    2004-01-01

    The theory model of fiber optical parametric amplifier (FOPA) was introduced, which is based on optical nonlinear effect. And then numerical simulation was done to analyze and discuss the gain spectral characteristics of one-pump and two-pump FOPA. The results show that for one-pump FOPA, when pump wavelength is near to fiber zero-dispersion wavelength(ZDW), the gain flatness is better, and with the increase of the pump power, fiber length and its nonlinear coefficient, the gain value will increase while the gain bandwidth will become narrow. For two-pump FOPA, when the pump central wavelength is near to fiber ZDW, the gain flatness is better. Moreover, by decreasing the space of two pumps wavelength, the gain flatness can be improved. Finally, some problems existing in FOPA were addressed.

  14. Optical antenna gain. I - Transmitting antennas

    Science.gov (United States)

    Klein, B. J.; Degnan, J. J.

    1974-01-01

    The gain of centrally obscured optical transmitting antennas is analyzed in detail. The calculations, resulting in near- and far-field antenna gain patterns, assume a circular antenna illuminated by a laser operating in the TEM-00 mode. A simple polynomial equation is derived for matching the incident source distribution to a general antenna configuration for maximum on-axis gain. An interpretation of the resultant gain curves allows a number of auxiliary design curves to be drawn that display the losses in antenna gain due to pointing errors and the cone angle of the beam in the far field as a function of antenna aperture size and its central obscuration. The results are presented in a series of graphs that allow the rapid and accurate evaluation of the antenna gain which may then be substituted into the conventional range equation.

  15. Optical antenna gain. 1: transmitting antennas.

    Science.gov (United States)

    Klein, B J; Degnan, J J

    1974-09-01

    The gain of centrally obscured optical transmitting antennas is analyzed in detail. The calculations, resulting in near- and far-field antenna gain patterns, assume a circular antenna illuminated by a laser operating in the TEM(00) mode. A simple polynomial equation is derived for matching the incident source distribution to a general antenna configuration for maximum on-axis gain. An interpretation of the resultant gain curves allows a number of auxiliary design curves to be drawn that display the losses in antenna gain due to pointing errors and the cone angle of the beam in the far field as a function of antenna aperture size and its central obscuration. The results are presented in a series of graphs that allow the rapid and accurate evaluation of the antenna gain which may then be substituted into the conventional range equation.

  16. Microchannel plate modal gain variations with temperature

    Science.gov (United States)

    Slater, David C.; Timothy, J. G.

    1993-01-01

    Measurements of the modal gain of two high-gain curved-channel microchannel plates (MCPs) at various operating temperatures are presented. Both MCPs were fabricated from the Long Life glass with 12-micron diam channels on 15-micron centers. The modal gain was found to decrease with increasing temperature at a rate of -0.1 percent C. This reduction of gain with temperature is attributed primarily to an axial temperature gradient along each MCP channel creating a nonuniform electric field within the channel that lowers the effective output gain. A lowering of the secondary electron yield resulting from increased phonon scattering of secondary electrons released within the walls of the MCP channels was assessed, but was found to have a negligible contribution to the drop in gain with temperature.

  17. In-Phase Wavelength Conversion Based On Cross-Gain Modulation in Semiconductor Optical Amplifier

    Institute of Scientific and Technical Information of China (English)

    ZHANG Xinliang; HUANG Dexiu; SUN Junqiang; LIU Deming; YI Heqing

    2000-01-01

    In-phase wavelength conversion based on cross-gain modulation in a semiconductor optical amplifier biased around critical threshold current has been demonstrated. The converted signal and the pump signal have the same bit sequence 1101011000. The stimulated emission competition between the amplification of input signals and the amplified spontaneous emission was used to illustrate the conversion mechanism. Experiment results showed that in-phase wavelength conversion can be achieved with simple structure and high output extinction ratio.

  18. Emission Trading under the Kyoto Protocol

    Energy Technology Data Exchange (ETDEWEB)

    Holtsmark, Bjart; Hagem, Cathrine

    1998-12-01

    This report discusses the potential gains from emission trading and raises some crucial questions. It shows that the total costs of the Kyoto Protocol could be reduced by about 95% through emission trading. Emission trading is an option also in the domestic arenas. The governments of the Annex B countries may allocate emission quotas to local enterprises as emission permits. Thus new markets for greenhouse gas emission quotas may emerge, domestically and internationally. It is emphasized that emission trading at the national and international levels must be discussed separately. The Nordic governments, for example, will find several good reasons for supporting emission trading at the international level if not necessarily domestically. The Nordic countries have already implemented domestic taxes on CO{sub 2} emissions and this tax policy could be sustained while these governments support and take part in emission trading at the international level.The report also considers a possible side effect of emission trading: free emission trading among Annex B countries could reduce the total abatement compared to a non-tradable policy as a consequence of the fact that some of the countries that are in transition to a market economy may be given emission limitations above their business-as-usual emissions. 40 refs., 7 figs., 4 tabs.

  19. Refixation saccades with normal gain values

    DEFF Research Database (Denmark)

    Korsager, Leise Elisabeth Hviid; Faber, Christian Emil; Schmidt, Jesper Hvass

    2017-01-01

    Refixation saccades with normal gain value occur more frequently with increasing age. The phenomenon has also been observed in different vestibular disorders. In this case, we present a young male with normal gain value and refixation saccades tested with the video head impulse test (vHIT) the da...

  20. GaInNAs laser gain

    Energy Technology Data Exchange (ETDEWEB)

    CHOW,WENG W.; JONES,ERIC D.; MODINE,NORMAND A.; KURTZ,STEVEN R.; ALLERMAN,ANDREW A.

    2000-05-23

    The optical gain spectra for GaInNAs/GaAs quantum wells are computed using a microscopic laser theory. From these spectra, the peak gain and carrier radiative decay rate as functions of carrier density are determined. These dependences allow the study of the lasing threshold current density of GaInNAs/GaAs quantum well structures.

  1. Gain leveling using electromagnetically induced transparency

    Energy Technology Data Exchange (ETDEWEB)

    Zhuo, Z.C. [State Key Laboratory of Integrated Opto-Electronics, Jilin University, Changchun 130023 (China); Su, X.M. [Key Laboratory of Coherent Light and Atom and Molecule Spectroscopy of Ministry of Education, Jilin University, Changchun 130023 (China)]. E-mail: euxmsu@public.cc.jl.cn; Zhang, Y.S. [State Key Laboratory of Integrated Opto-Electronics, Jilin University, Changchun 130023 (China)

    2005-02-28

    We propose and demonstrate a scheme of gain leveling for erbium-doped fiber amplifier (EDFA) by applying a strong coherent field to a three level amplified system using electromagnetically induced transparency. Due to the effect of this coupling field on the Stark-splitting sublevels, this scheme can be realized a flat gain operating around 1.53 {mu}m.

  2. 75 FR 43615 - Program Integrity: Gainful Employment

    Science.gov (United States)

    2010-07-26

    ... Education 34 CFR Part 668 Program Integrity: Gainful Employment; Proposed Rule #0;#0;Federal Register / Vol... RIN 1840-AD04 Program Integrity: Gainful Employment AGENCY: Office of Postsecondary Education... against the education and training (and increased employment income) that higher education can provide....

  3. Determinants of inadequate weight gain in pregnancy.

    Science.gov (United States)

    Popa, Alina Delia; Niţă, Otilia; Popescu, Raluca Maria; Gherasim, Andreea; Arhire, Lidia luliana; Mihalache, Laura; Graur, Mariana

    2014-01-01

    The aim of the study was to explore the anthropometric maternal characteristics and prenatal care as determinants of pregnancy weight gain. We conducted a cross-sectional study on a total of 400 pregnant women admitted to Cuza-Vodă Obstetrics and Gynecology Clinical Hospital, Iaşi. Information on demographic characteristics, number of prenatal visits, and education on nutrition and food changes occurring during pregnancy were recorded in a structured questionnaire. Anthropometric parameters analyzed were pregestational BMI (body mass index) and weight gain during pregnancy. Weight gain was associated with pregestational BMI category. An increase in weight more than recommended occured more frequently in overweight (53.1%) and obese women (66.7%) (p < 0.001). Weight gain during pregnancy was related to area of residence, age, APCU (adequate prenatal care utilization) index. The multivariate analysis identified the following variables as significant determinants of pregnancy weight gain: inadequate prenatal care, BMI and changes in diet. Pregestational BMI and changes in diet during pregnancy identified as determinants of weight gain suggests that overweight and underweight women must carefully be counseled regarding recommendations for weight gain in pregnancy. Tracking diet changes is important to ensure that a weight gain lies within the guidelines recommendations.

  4. Maximum gain of Yagi-Uda arrays

    DEFF Research Database (Denmark)

    Bojsen, J.H.; Schjær-Jacobsen, Hans; Nilsson, E.

    1971-01-01

    Numerical optimisation techniques have been used to find the maximum gain of some specific parasitic arrays. The gain of an array of infinitely thin, equispaced dipoles loaded with arbitrary reactances has been optimised. The results show that standard travelling-wave design methods are not optimum....... Yagi–Uda arrays with equal and unequal spacing have also been optimised with experimental verification....

  5. Gain scheduling using the youla parameterization

    DEFF Research Database (Denmark)

    Niemann, H.H.; Stoustrup, Jakob

    1999-01-01

    Gain scheduling controllers are considered in this paper. The gain scheduling problem where the scheduling parameter vector theta cannot be measured directly, but needs to be estimated is considered. An estimation of the scheduling vector theta has been derived by using the Youla parameterization...

  6. Gain Shift Corrections at Chi-Nu

    Energy Technology Data Exchange (ETDEWEB)

    Brown, Tristan Brooks [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Univ. of Massachusetts, Lowell, MA (United States). Dept. of Physics and Applied Physics; Devlin, Matthew James [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-08-30

    Ambient conditions have the potential to cause changes in liquid scintillator detector gain that vary with time and temperature. These gain shifts can lead to poor resolution in both energy as well as pulse shape discrimination. In order to correct for these shifts in the Chi-Nu high energy array, a laser system has been developed for calibration of the pulse height signals.

  7. Energy Gaining Windows for Residental Buildings

    DEFF Research Database (Denmark)

    Kragh, Jesper; Laustsen, Jacob Birck; Svendsen, Svend

    This paper presents some of the research done during the last 8 years at the Technical University of Denmark developing improved low-energy window solutions. The focus has been on maximizing the net energy gain of windows for residential buildings. The net energy gain of windows is the solar gain...... windows have already been developed and prototypes constructed for laboratory test and a third generation of the window design is now in the developing and designing face in a new project. The first window constructed was made of wood profiles and a low-energy double glazing unit. The second and third...... and longer durability of the window. The glazing in these fiber reinforced polyester windows is both unsealed and sealed triple glazing units. To increase the net energy gain slim frame profiles have been developed to increase the glazing area and thereby the solar gain. The challenge when developing slim...

  8. Gain control mechanisms in spinal motoneurons

    Directory of Open Access Journals (Sweden)

    Michael David Johnson

    2014-07-01

    Full Text Available Motoneurons provide the only conduit for motor commands to reach muscles. For many years, motoneurons were in fact considered to be little more than passive wires. Systematic studies in the past 25 years however have clearly demonstrated that the intrinsic electrical properties of motoneurons are under strong neuromodulatory control via multiple sources. The discovery of potent neuromodulation from the brainstem and its ability to change the gain of motoneurons shows that the passive view of the motor output stage is no longer tenable. A mechanism for gain control at the motor output stage makes good functional sense considering our capability of generating an enormous range of forces, from very delicate (e.g. putting in a contact lens to highly forceful (emergency reactions. Just as sensory systems need gain control to deal with a wide dynamic range of inputs, so to might motor output need gain control to deal with the wide dynamic range of the normal movement repertoire. Two problems emerge from the potential use of the brainstem monoaminergic projection to motoneurons for gain control. First, the projection is highly diffuse anatomically, so that independent control of the gains of different motor pools is not feasible. In fact, the system is so diffuse that gain for all the motor pools in a limb likely increases in concert. Second, if there is a system that increases gain, probably a system to reduce gain is also needed. In this review, we summarize recent studies that show local inhibitory circuits within the spinal cord, especially reciprocal and recurrent inhibition, have the potential to solve both of these problems as well as constitute another source of gain modulation.

  9. Optical gain in single tensile-strained germanium photonic wire.

    Science.gov (United States)

    de Kersauson, M; El Kurdi, M; David, S; Checoury, X; Fishman, G; Sauvage, S; Jakomin, R; Beaudoin, G; Sagnes, I; Boucaud, P

    2011-09-12

    We have investigated the optical properties of tensile-strained germanium photonic wires. The photonic wires patterned by electron beam lithography (50 μm long, 1 μm wide and 500 nm thick) are obtained by growing a n-doped germanium film on a GaAs substrate. Tensile strain is transferred in the germanium layer using a Si₃N₄ stressor. Tensile strain around 0.4% achieved by the technique corresponds to an optical recombination of tensile-strained germanium involving light hole band around 1690 nm at room temperature. We show that the waveguided emission associated with a single tensile-strained germanium wire increases superlinearly as a function of the illuminated length. A 20% decrease of the spectral broadening is observed as the pump intensity is increased. All these features are signatures of optical gain. A 80 cm⁻¹ modal optical gain is derived from the variable strip length method. This value is accounted for by the calculated gain material value using a 30 band k · p formalism. These germanium wires represent potential building blocks for integration of nanoscale optical sources on silicon.

  10. High attrition among HIV-infected patients with advanced disease treated in an intermediary referral center in Maputo, Mozambique

    Directory of Open Access Journals (Sweden)

    Lucas Molfino

    2014-04-01

    Full Text Available Background: In Mozambique, antiretroviral therapy (ART scale-up has been successfully implemented. However, attrition in care remains a major programmatic challenge. In 2009, an intermediary-level HIV referral center was created in Maputo to ensure access to specialized care for HIV-infected patients with complications (advanced clinical-immunological stage, Kaposi sarcoma, or suspected ART failure. Objective: To determine the attrition from care and to identify risk factors that lead to high attrition among patients referred to an intermediary-level HIV referral center. Design: This was a retrospective cohort study from 2009 to 2011. Results: A total of 1,657 patients were enrolled, 847 (51% were men, the mean age was 36 years (standard deviation: 11, the mean CD4 count was 27 cells/µl (interquartile range: 11–44, and one-third were severely malnourished. The main reasons for referral were advanced clinical stages (WHO stages 3 and 4, and CD4 count <50 cells/µl in 70% of the cases, and 19% had Kaposi sarcoma. The overall attrition rate was 28.7 per 100 person-years (PYs – the mortality rate was 5.0 (95% confidence interval [CI]: 4.2–5.9 per 100 PYs, and the loss-to-follow-up rate was 23.7 (95% CI: 21.9–25.6 per 100 PYs. There were 793 attritions – 137 deaths and 656 lost to follow-up (LTFU; 77% of all attrition happened within the first year. The factors independently associated with attrition were male sex (adjusted hazard ratio [aHR]: 1.15, 95% CI: 1.0–1.3, low body mass index (aHR: 1.51, 95% CI: 1.2–1.8, WHO clinical stage 3 or 4 (aHR: 1.30, 95% CI: 1.0–1.6; and aHR: 1.91, 95% CI: 1.4–2.5, later year of enrollment (aHR 1.61, 95% CI 1.3–1.9, and ‘being already on ART’ at enrollment (aHR 13.71, 95% CI 11.4–16.4. Conclusions: Attrition rates among HIV-infected patients enrolled in an intermediary referral center were high, mainly related to advanced stage of clinical disease. Measures are required to address this

  11. Intrinsic gain modulation and adaptive neural coding.

    Directory of Open Access Journals (Sweden)

    Sungho Hong

    Full Text Available In many cases, the computation of a neural system can be reduced to a receptive field, or a set of linear filters, and a thresholding function, or gain curve, which determines the firing probability; this is known as a linear/nonlinear model. In some forms of sensory adaptation, these linear filters and gain curve adjust very rapidly to changes in the variance of a randomly varying driving input. An apparently similar but previously unrelated issue is the observation of gain control by background noise in cortical neurons: the slope of the firing rate versus current (f-I curve changes with the variance of background random input. Here, we show a direct correspondence between these two observations by relating variance-dependent changes in the gain of f-I curves to characteristics of the changing empirical linear/nonlinear model obtained by sampling. In the case that the underlying system is fixed, we derive relationships relating the change of the gain with respect to both mean and variance with the receptive fields derived from reverse correlation on a white noise stimulus. Using two conductance-based model neurons that display distinct gain modulation properties through a simple change in parameters, we show that coding properties of both these models quantitatively satisfy the predicted relationships. Our results describe how both variance-dependent gain modulation and adaptive neural computation result from intrinsic nonlinearity.

  12. The effect of gain saturation in a gain compensated perfect lens

    CERN Document Server

    Andresen, Marte P Hatlo; Haakestad, Magnus W; Krogstad, Harald E; Skaar, Johannes

    2010-01-01

    The transmission of evanescent waves in a gain-compensated perfect lens is discussed. In particular, the impact of gain saturation is included in the analysis, and a method for calculating the fields of such nonlinear systems is developed. Gain compensation clearly improves the resolution; however, a number of nonideal effects arise as a result of gain saturation. The resolution associated with the lens is strongly dependent on the saturation constant of the active medium.

  13. 資訊檢索指導員評鑑量表之探討 A Study of Evaluation Checklist on the Performance of Information Intermediaries

    Directory of Open Access Journals (Sweden)

    Shih-hsion Huang

    1998-09-01

    Full Text Available 無The main purpose of this study is to induce important factors of a good performance of information intermediaries by developing the evaluation checklist. By employing the Delphi Method, first step is to collect Delphi panel's (people who are/were in charge of reference and information services in university libraries opinions by open questionnaire. Upon them, a constructive questionnaire is developed and sent out to experts to rank on the degree of importance of evaluation items. A final consensus among the experts is gotten in the second round of Delphi process. An evaluation checklist of information intermediaries is established based on the study result. According the result of the study, the final evaluation checklist comprised seven parts with 191 items totally. That can be a reference to related fields and following researches.

  14. Role of intermediary cells in Peltodon radicans (Lamiaceae in the transfer of calcium and formation of calcium oxalate crystals

    Directory of Open Access Journals (Sweden)

    Elder Antônio Sousa Paiva

    2005-01-01

    Full Text Available With the objective of studying the connection between calcium oxalate crystals formation and the phloem, fragments of leaves of Peltodon radicans Pohl (Lamiaceae were fixed and processed, for light and electron-transmission microscopes. It was observed that the crystals occurred in the cells of the bundle sheath, juxtaposed in relation to the phloem. Intermediary cells established a connection between the sieve element and crystal-bearing sheath cells. Calcium was present abundantly in the cytoplasm of sheath cells as calcium oxalate crystals. The presence of calcium was also detected in the intermediary cells, but in the sieve elements it was not detected. There was, therefore, an increasing concentration gradient of calcium in the sieve elements from sheath cells. Thus, we hypothesized that the formation of calcium oxalate crystals regulates calcium levels in the sieve elements.Com o objetivo de estudar a relação entre cristais de oxalato de cálcio e floema, fragmentos de folhas de Peltodon radicans foram fixados e processados, segundo métodos usuais, para estudos ao microscópio de luz e eletrônico de transmissão. Observou-se que os cristais ocorrem nas células da bainha do feixe, lateralmente em relação ao floema. Células intermediárias estabelecem conexão entre elemento crivado e células da bainha, portadoras de cristais, com crescimento intrusivo entre estas. Íons cálcio são abundantes no citoplasma das células da bainha que contém cristais de oxalato de cálcio. Nas células intermediárias a detecção ultra-citoquímica de cálcio também apresentou resultados positivos, enquanto nos elementos crivados a presença deste íon não foi constatada. Há, portanto, um gradiente crescente de concentração de cálcio dos elementos crivados para as células da bainha. Assim, formulamos a hipótese de que a formação de cristais de oxalato de cálcio tem, em P. radicans, o objetivo de controlar os níveis de cálcio citoss

  15. Carbon Isotope Characterization of Organic Intermediaries in Hydrothermal Hydrocarbon Synthesis by Pyrolysis-GC-MS-C-IRMS

    Science.gov (United States)

    Socki, Richard A.; Fu, Qi; Niles, Paul B.

    2010-01-01

    We report results of experiments designed to characterize the carbon isotope composition of intermediate organic compounds produced as a result of mineral surface catalyzed reactions. The impetus for this work stems from recently reported detection of methane in the Martian atmosphere coupled with evidence showing extensive water-rock interaction during Martian history. Abiotic formation by Fischer-Tropsch-type (FTT) synthesis during serpentinization reactions may be one possible process responsible for methane generation on Mars, and measurement of carbon and hydrogen isotopes of intermediary organic compounds can help constrain the origin of this methane. Of particular interest within the context of this work is the isotopic composition of organic intermediaries produced on the surfaces of mineral catalysts (i.e. magnetite) during hydrothermal experiments, and the ability to make meaningful and reproducible isotope measurements. Our isotope measurements utilize a unique analytical technique combining Pyrolysis-Gas Chromatograph-Mass Spectrometry-Combustion-Isotope Ratio Mass Specrometry (Py-GC-MS-C-IRMS). Others have conducted similar pyrolysis-IRMS experiments on low molecular weight organic acids (Dias, et al, Organic Geochemistry, 33 [2002]). Our technique differs in that it carries a split of the pyrolyzed GC-separated product to a Thermo DSQ-II quadrupole mass spectrometer as a means of making qualitative and semi-quantitative compositional measurements of the organic compounds. A sample of carboxylic acid (mixture of C1 through C6) was pyrolyzed at 100 XC and passed through the GC-MS-C-IRMS (combusted at 940 XC). In order to test the reliability of our technique we compared the _13C composition of different molecular weight organic acids (from C1 through C6) extracted individually by the traditional sealed-tube cupric oxide combustion (940 XC) method with the _13C produced by our pyrolysis technique. Our data indicate that an average 4.3. +/-0.5. (V

  16. A Study of the Value of Information and the Effect on Value of Intermediary Organizations, Timeliness of Services & Products, and Comprehensiveness of the EDB. Volume 1: The Value of Libraries as an Intermediary Information Service; Volume 2: The Value of the Network Energy Software Center and the Radiation Shielding Information Center; Volume 3: The Effects of Timeliness and Comprehensiveness on Value.

    Science.gov (United States)

    King Research, Inc., Rockville, MD.

    This document reports in three volumes the results of a series of surveys designed to: (1) determine what contribution intermediary information transfer organizations such as libraries and information analysis centers make to the value of information; (2) assess the value of two somewhat different software information analysis centers and the…

  17. Energy Gaining Windows for Residental Buildings

    DEFF Research Database (Denmark)

    Kragh, Jesper; Laustsen, Jacob Birck; Svendsen, Svend

    2008-01-01

    windows have already been developed and prototypes constructed for laboratory test and a third generation of the window design is now in the developing and designing face in a new project. The first window constructed was made of wood profiles and a low-energy double glazing unit. The second and third......This paper presents some of the research done during the last 8 years at the Technical University of Denmark developing improved low-energy window solutions. The focus has been on maximizing the net energy gain of windows for residential buildings. The net energy gain of windows is the solar gain...

  18. Point Information Gain and Multidimensional Data Analysis

    Directory of Open Access Journals (Sweden)

    Renata Rychtáriková

    2016-10-01

    Full Text Available We generalize the point information gain (PIG and derived quantities, i.e., point information gain entropy (PIE and point information gain entropy density (PIED, for the case of the Rényi entropy and simulate the behavior of PIG for typical distributions. We also use these methods for the analysis of multidimensional datasets. We demonstrate the main properties of PIE/PIED spectra for the real data with the examples of several images and discuss further possible utilizations in other fields of data processing.

  19. TCAD simulation of Low Gain Avalanche Detectors

    Science.gov (United States)

    Dalal, Ranjeet; Jain, Geetika; Bhardwaj, Ashutosh; Ranjan, Kirti

    2016-11-01

    In the present work, detailed simulation using Technology Computer Aided Design (TCAD) tool, Silvaco for non-irradiated and irradiated LGAD (Low Gain Avalanche Detector) devices has been carried out. The effects of different design parameters and proton irradiation on LGAD operation are discussed in detail. An already published effective two trap bulk damage model is used to simulate the radiation damage without implementing any acceptor removal term. The TCAD simulation for irradiated LGAD devices produce decreasing gain with increasing fluence, similar to the measurement results. The space charge density and electric field distribution are used to illustrate the possible reasons for the degradation of gain of the irradiated LGAD devices.

  20. Nonunity gain minimal-disturbance measurement

    DEFF Research Database (Denmark)

    Sabuncu, Metin; Mišta, L.; Fiurášek, J.

    2007-01-01

    We propose and experimentally demonstrate an optimal nonunity gain Gaussian scheme for partial measurement of an unknown coherent state that causes minimal disturbance of the state. The information gain and the state disturbance are quantified by the noise added to the measurement outcomes and to...... and to the output state, respectively. We derive the optimal trade-off relation between the two noises and we show that the tradeoff is saturated by nonunity gain teleportation. Optimal partial measurement is demonstrated experimentally using a linear optics scheme with feedforward....

  1. A novel "gain chip" concept for high-power lasers (Conference Presentation)

    Science.gov (United States)

    Li, Min; Li, Mingzhong; Wang, Zhenguo; Yan, Xiongwei; Jiang, Xinying; Zheng, Jiangang; Cui, Xudong; Zhang, Xiaomin

    2017-05-01

    High-power lasers, including high-peak power lasers (HPPL) and high-average power lasers (HAPL), attract much interest for enormous variety of applications in inertial fusion energy (IFE), materials processing, defense, spectroscopy, and high-field physics research. To meet the requirements of high efficiency and quality, a "gain chip" concept is proposed to properly design the pumping, cooling and lasing fields. The gain chip mainly consists of the laser diode arrays, lens duct, rectangle wave guide and slab-shaped gain media. For the pumping field, the pump light will be compressed and homogenized by the lens duct to high irradiance with total internal reflection, and further coupled into the gain media through its two edge faces. For the cooling field, the coolant travels along the flow channel created by the adjacent slabs in the other two edge-face direction, and cool the lateral faces of the gain media. For the lasing field, the laser beam travels through the lateral faces and experiences minimum thermal wavefront distortions. Thereby, these three fields are in orthogonality offering more spatial freedom to handle them during the construction of the lasers. Transverse gradient doping profiles for HPPL and HAPL have been employed to achieve uniform gain distributions (UGD) within the gain media, respectively. This UGD will improve the management for both amplified spontaneous emission (ASE) and thermal behavior. Since each "gain chip" has its own pump source, power scaling can be easily achieved by placing identical "gain chips" along the laser beam axis without disturbing the gain and thermal distributions. To detail our concept, a 1-kJ pulsed amplifier is designed and optical-to-optical efficiency up to 40% has been obtained. We believe that with proper coolant (gas or liquid) and gain media (Yb:YAG, Nd:glass or Nd:YAG) our "gain chip" concept might provide a general configuration for high-power lasers with high efficiency and quality.

  2. High-Content Positional Biosensor Screening Assay for Compounds to Prevent or Disrupt Androgen Receptor and Transcriptional Intermediary Factor 2 Protein–Protein Interactions

    OpenAIRE

    Hua, Yun; Shun, Tong Ying; Strock, Christopher J.; Johnston, Paul A.

    2014-01-01

    The androgen receptor–transcriptional intermediary factor 2 (AR-TIF2) positional protein–protein interaction (PPI) biosensor assay described herein combines physiologically relevant cell-based assays with the specificity of binding assays by incorporating structural information of AR and TIF2 functional domains along with intracellular targeting sequences and fluorescent reporters. Expression of the AR-red fluorescent protein (RFP) “prey” and TIF2-green fluorescent protein (GFP) “bait” compon...

  3. 企业中间层理论在煤炭流通中的作用分析%Function of Enterprise Intermediary Theory in Coal Circulation

    Institute of Scientific and Technical Information of China (English)

    韩信美; 林晓言

    2012-01-01

    The paper first analyzes the necessity and function of the intermediary bodies in the coal market from a theoretical perspective and then reveals through analysis the current status of the coal market of China and the problems faced by the intermediary organizations in coal transaction, mainly including (1) non-optimal market system in coal transaction; (2) possible racketeering committed by the intermediary organizations; (3) lack of efficient supervision and rampant misappropriation and misuse for one' s own end. At the end, in view of these problems, the paper proposes the corresponding suggestions for the intermediary organizations to better play their role in coal transaction.%首先从企业的中间层组织理论角度分析煤炭交易市场中的中间层组织存在的必要性和作用;其次,分析目前我国煤炭交易市场现状、中间层组织在煤炭交易中存在的问题,主要有:(1)煤炭交易市场体系不完善;(2)中间层组织有潜在的“敲竹杠”行为;(3)监管缺位,中饱私囊现象严重;最后针对中间层运营中存在的问题,为更好地发挥中间层组织在煤炭交易中的作用提出相应的建议.

  4. Kerkhoff v Minister of Justice and Constitutional Development 2011 2 SACR 109 (GNP: Intermediary Appointment Reports and a Child's Right to Privacy Versus the Right of an Accused to Access to Information

    Directory of Open Access Journals (Sweden)

    Mildred Bekink

    2017-01-01

    Full Text Available General consensus exists that the adversarial nature of the South African criminal procedure with its often aggressive cross-examination of a witness, sometimes by an accused himself, will in most cases expose a child to undue mental stress or suffering when having to testify in court. In confirmation of this fact and with a notion to shield child witnesses from the stress or suffering when having to testify in the presence of an accused the function of an intermediary was introduced with the insertion of section 170A into the Criminal Procedure Act 51 of 1977. In terms of section 170A(1 a court may if it appears to such court that it would expose any witness under the biological or mental age of eighteen years to undue mental stress or suffering if he or she testified at such hearing, appoint a competent person as an intermediary in order for the witness to give evidence through that intermediary. Section 170A(1 contemplates that a child complainant will be assessed prior to testifying in court in order to determine whether the services of an intermediary should be used. If the assessment reveals that the services of an intermediary are needed, then the state must arrange for an intermediary to be available at the commencement of the trail. The aforementioned procedure of section 170A(1 was followed in Kerkhoff v Minister of Justice and Constitutional Development 2011 2 SACR 109 (GP and is the subject of this discussion.

  5. Stimulated emission of surface plasmon polaritons

    CERN Document Server

    Noginov, M A; Mayy, M F; Ritzo, B A; Noginova, N; Podolskiy, V A

    2008-01-01

    We have observed laser-like emission of surface plasmon polaritons (SPPs) decoupled to the glass prism in an attenuated total reflection setup. SPPs were excited by optically pumped molecules in a polymeric film deposited on the top of the silver film. Stimulated emission was characterized by a distinct threshold in the input-output dependence and narrowing of the emission spectrum. The observed stimulated emission and corresponding to it compensation of the metallic absorption loss by gain enables many applications of metamaterials and nanoplasmonic devices.

  6. Development of Source-Receptor matrix over South Korea in support of GAINS-Korea model

    Science.gov (United States)

    Choi, K. C.; Woo, J. H.; Kim, H. K.; Lee, Y. M.; Kim, Y.; Heyes, C.; Lee, J. B.; Song, C. K.; Han, J.

    2014-12-01

    A comprehensive and combined analysis of air pollution and climate change could reveal important synergies of emission control measures, which could be of high policy relevance. IIASA's GAINS model (The Greenhouse gas - Air pollution Interactions and Synergies) has been developed as a tool to identify emission control strategies that achieve given targets on air quality and greenhouse gas emissions at least costs. The GAINS-Korea Model, which is being jointly developed by Konkuk University and IIASA, should play an important role in understanding the impact of air quality improvements across the regions in Korea. Source-Receptor relationships (S-R) is an useful methodology in air pollution studies to determine the areas of origin of chemical compounds at receptor point, and thus be able to target actions to reduce pollutions. The GAINS model can assess the impact of emission reductions of sources on air quality in receptor regions based on S-R matrix, derived from chemical transport model. In order to develop S-R matrix for GAINS-Korea, the CAMx model with PSAT/OSAT tools was applied in this study. The coarse domain covers East Asia, and a nesting domain as main research area was used for Korea peninsula. To evaluate of S-R relationships, a modeling domain is divided into sixteen regions over South Korea with three outside of S. Korea countries (China, N. Korea and Japan) for estimating transboundary contributions. The results of our analysis will be presented at the conference.

  7. Narrow line width operation of a 980 nm gain guided tapered diode laser bar

    DEFF Research Database (Denmark)

    Vijayakumar, Deepak; Jensen, Ole Bjarlin; Barrientos-Barria, Jessica;

    2011-01-01

    We demonstrate two different schemes for the spectral narrowing of a 12 emitter 980 nm gain guided tapered diode laser bar. In the first scheme, a reflective grating has been used in a Littman Metcalf configuration and the wavelength of the laser emission could be narrowed down from more than 5.5...

  8. How Local Intermediaries Improve the Effectiveness of Public Payment for Ecosystem Services Programs: The Role of Networks and Agri-Environmental Assistance

    Directory of Open Access Journals (Sweden)

    Sarah Schomers

    2015-10-01

    Full Text Available Large governmental payments for ecosystem services programs (PES have frequently been criticized for their limited environmental effectiveness. The use of local intermediaries has been considered as one possibility for improving the environmental effectiveness of such programs. German Landcare Associations (LCAs have been identified as one intermediary that holds the potential to positively influence the implementation of agri-environmental measures (AEMs. This paper empirically assesses the involvement of LCAs in the context of AEM implementation in Germany. An online questionnaire was distributed to all LCAs in Germany. In a first step, we examine if LCAs (1 provide social networks between stakeholders and (2 provide agri-environmental information and assistance to farmers. In a second step, the LCAs assess (3 their perception of how strongly their work influences farmers’ participation in PES schemes and (4 if they pursue the spatial targeting of AEMs. In a third step, we relate the relative level of social networks and the provision of agri-environmental information and assistance to their stated influence on farmers’ participation in and spatial targeting of AEMs. Finally we derive overall conclusions on how intermediaries can enhance the effectiveness of PES programs in general.

  9. Early Weight Gain Predicting Later Weight Gain Among Depot Medroxyprogesterone Acetate Users

    Science.gov (United States)

    LE, Yen-Chi L.; RAHMAN, Mahbubur; BERENSON, Abbey B.

    2009-01-01

    Objective To examine if early weight gain in depot medroxyprogesterone acetate (DMPA) users predicts continued excessive weight gain and to identify risk factors of early weight gain in DMPA users. Methods DMPA users (N=240) were assessed prior to initiating contraception and every 3 months for 36 months. Early weight gain was defined as over 5% baseline weight gain within 6 months of DMPA use. Mean weight gain at 6-month intervals was estimated based on early weight gain status (at or below 5% gain vs. above 5% gain). Multiple logistic and mixed-model regression analyses were used. Results About one-fourth of DMPA users had early weight gain. The mean weight gain of the at or below 5% group and above 5% group was 0.63 kg and 8.04 kg, 1.48 kg and 10.86 kg, and 2.49 kg and 11.08 kg after 12, 24, and 36 months (P < 0.001 at all observations), respectively. Early weight gainers also had a much steeper slope of weight gain over time than the regular weight gainers (0.35 kg/month vs. 0.08 kg/month, P < 0.001). Risk factors for early weight gain were: BMI less than 30 (OR 4.00, 95% confidence interval (CI): 1.513 – 10.455), parity (OR 2.23, 95% CI: 1.040 – 4.761), and self-reported increased appetite after 6 months of DMPA use (OR 3.06, 95% CI: 1.505 – 6.214). Conclusion Most DMPA users who gain excessive weight experience more than a 5% weight increase within 6 months. These data help physicians predict who is at risk of excessive gain and counsel them appropriately. PMID:19622988

  10. Microwave gain medium with negative refractive index.

    Science.gov (United States)

    Ye, Dexin; Chang, Kihun; Ran, Lixin; Xin, Hao

    2014-12-19

    Artificial effective media are attractive because of the fantastic applications they may enable, such as super lensing and electromagnetic invisibility. However, the inevitable loss due to their strongly dispersive nature is one of the fundamental challenges preventing such applications from becoming a reality. In this study, we demonstrate an effective gain medium based on negative resistance, to overcompensate the loss of a conventional passive metamaterial, meanwhile keeping its original negative-index property. Energy conservation-based theory, full-wave simulation and experimental measurement show that a fabricated sample consisting of conventional sub-wavelength building blocks with embedded microwave tunnel diodes exhibits a band-limited Lorentzian dispersion simultaneously with a negative refractive index and a net gain. Our work provides experimental evidence to the assertion that a stable net gain in negative-index gain medium is achievable, proposing a potential solution for the critical challenge current metamateiral technology faces in practical applications.

  11. Microwave gain medium with negative refractive index

    Science.gov (United States)

    Ye, Dexin; Chang, Kihun; Ran, Lixin; Xin, Hao

    2014-12-01

    Artificial effective media are attractive because of the fantastic applications they may enable, such as super lensing and electromagnetic invisibility. However, the inevitable loss due to their strongly dispersive nature is one of the fundamental challenges preventing such applications from becoming a reality. In this study, we demonstrate an effective gain medium based on negative resistance, to overcompensate the loss of a conventional passive metamaterial, meanwhile keeping its original negative-index property. Energy conservation-based theory, full-wave simulation and experimental measurement show that a fabricated sample consisting of conventional sub-wavelength building blocks with embedded microwave tunnel diodes exhibits a band-limited Lorentzian dispersion simultaneously with a negative refractive index and a net gain. Our work provides experimental evidence to the assertion that a stable net gain in negative-index gain medium is achievable, proposing a potential solution for the critical challenge current metamateiral technology faces in practical applications.

  12. Optical properties of nanowire metamaterials with gain

    DEFF Research Database (Denmark)

    Isidio de Lima, Joaquim Junior; Adam, Jost; Rego, Davi

    2016-01-01

    The transmittance, reflectance and absorption of a nanowire metamaterial with optical gain are numerically simulated and investigated. It is assumed that the metamaterial is represented by aligned silver nanowires embedded into a semiconductor matrix, made of either silicon or gallium phosphide....... The gain in the matrix is modeled by adding a negative imaginary part to the dielectric function of the semiconductor. It is found that the optical coefficients of the metamaterial depend on the gain magnitude in a non-trivial way: they can both increase and decrease with gain depending on the lattice...... constant of the metamaterial. This peculiar behavior is explained by the field redistribution between the lossy metal nanowires and the amplifying matrix material. These findings are significant for a proper design of nanowire metamaterials with low optical losses for diverse applications....

  13. Measuring Financial Gains from Genetically Superior Trees

    Science.gov (United States)

    George Dutrow; Clark Row

    1976-01-01

    Planting genetically superior loblolly pines will probably yield high profits.Forest economists have made computer simulations that predict financial gains expected from a tree improvement program under actual field conditions.

  14. Active Microwave Metamaterials Incorporating Ideal Gain Devices

    Directory of Open Access Journals (Sweden)

    Hao Xin

    2010-12-01

    Full Text Available Incorporation of active devices/media such as transistors for microwave and gain media for optics may be very attractive for enabling desired low loss and broadband metamaterials. Such metamaterials can even have gain which may very well lead to new and exciting physical phenomena. We investigate microwave composite right/left-handed transmission lines (CRLH-TL incorporating ideal gain devices such as constant negative resistance. With realistic lumped element values, we have shown that the negative phase constant of this kind of transmission lines is maintained (i.e., left-handedness kept while gain can be obtained (negative attenuation constant of transmission line simultaneously. Possible implementation and challenging issues of the proposed active CRLH-TL are also discussed.

  15. Optical properties of nanowire metamaterials with gain

    Science.gov (United States)

    Lima, Joaquim; Adam, Jost; Rego, Davi; Esquerre, Vitaly; Bordo, Vladimir

    2016-11-01

    The transmittance, reflectance and absorption of a nanowire metamaterial with optical gain are numerically simulated and investigated. It is assumed that the metamaterial is represented by aligned silver nanowires embedded into a semiconductor matrix, made of either silicon or gallium phosphide. The gain in the matrix is modeled by adding a negative imaginary part to the dielectric function of the semiconductor. It is found that the optical coefficients of the metamaterial depend on the gain magnitude in a non-trivial way: they can both increase and decrease with gain depending on the lattice constant of the metamaterial. This peculiar behavior is explained by the field redistribution between the lossy metal nanowires and the amplifying matrix material. These findings are significant for a proper design of nanowire metamaterials with low optical losses for diverse applications.

  16. High-Gain Magnetized Inertial Fusion

    Science.gov (United States)

    Slutz, Stephen A.; Vesey, Roger A.

    2012-01-01

    Magnetized inertial fusion (MIF) could substantially ease the difficulty of reaching plasma conditions required for significant fusion yields, but it has been widely accepted that the gain is not sufficient for fusion energy. Numerical simulations are presented showing that high-gain MIF is possible in cylindrical liner implosions based on the MagLIF concept [S. A. Slutz et al Phys. Plasmas 17, 056303 (2010)PHPAEN1070-664X10.1063/1.3333505] with the addition of a cryogenic layer of deuterium-tritium (DT). These simulations show that a burn wave propagates radially from the magnetized hot spot into the surrounding much denser cold DT given sufficient hot-spot areal density. For a drive current of 60 MA the simulated gain exceeds 100, which is more than adequate for fusion energy applications. The simulated gain exceeds 1000 for a drive current of 70 MA.

  17. Theoretical discussion on gain guided and index antiguided fiber laser by variational gain saturation factor

    Science.gov (United States)

    Wang, X.; Xiong, C.; Luo, J.

    2011-03-01

    The variational gain saturation factor was suggested for the theoretical model of side pumping gain guided and index antiguided fiber laser, because of the invalid definition of constant saturation power owing to the large scale core area on the cross section. The variational gain saturation factor was defined by an integral formula and obtained by a numerical method. By this approach, the theoretical model of the side pump gain guided and index antiguided fiber laser was analyzed as regards the influence of output laser power by the index step and gain coefficient.

  18. Tradeoff on gain-flatness and gain-stabilization of erbium doped fiber amplifier with FBGs

    Science.gov (United States)

    Buyin, Garidi; OuYang, Yunlun; Ma, Yu; Chang, Jinlong; Liu, Changxing; Yang, Jiuru

    2014-07-01

    It is a challenge to get gain-stabilization and gain-flatness of erbium doped fiber amplifier (EDFA) in C-band, simultaneously. In this article, we establish a gain-clamped EDFA model based uniform fiber grating-pair and optimize the reflectivity of grating by the designed targets. The tradeoff between stabilization and flatness can be obtained when an ideal reflectivity is adopted. The numerical results show that the gain-stabilization is controlled in +/-0.1dB and gain-flatness is less than +/-1.41dB in the range from 1535nm to 1565nm.

  19. Requirements for intermediaries and advisors in the area of mortgages resulting from Mortgage Credit Directive – implications for Poland

    Directory of Open Access Journals (Sweden)

    Krzysztof Waliszewski

    2015-10-01

    Full Text Available The dynamic development of the mortgage market, especially in the period before the current financial crisis, revealed that within the EU there are local mortgage credit markets and that it is necessary to harmonize the rules of the system and consumer protection within the Community. The intention of the creators of the Mortgage Credit Directive was to organize the mortgage lending market for residential purposes and make it transparent, as well as increase the safety of the consumer credit market, along the lines of what took place earlier in the consumer credit market regulations (The Consumer Credit Directives no. 2008/48/EC and earlier no. 87/102/EEC. The Mortgage Credit Directive implies for lenders - credit institutions to act at every stage of the lending process with respect to the consumer’s interest and to provide them with adequate services for their needs. Due to the large role of indirect distribution channels of mortgages by banks there are certain requirements for intermediaries, brokers and credit advisors. The implementation term of the Directive, appointed for March 2016, implies action to be taken in order to implement the provisions of this Directive into Polish law. The legislative process is being conducted by the Ministry of Finance and supported by the Group on implementation of the Mortgage Credit Directive operating with the Council of Financial Market Development.

  20. CONDITIONS FOR CSR MICROBUNCHING GAIN SUPPRESSION

    Energy Technology Data Exchange (ETDEWEB)

    Tsai, Cheng Ying [Virginia Polytechnic Inst. and State Univ. (Virginia Tech), Blacksburg, VA (United States); Douglas, David R. [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Li, Rui [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Tennant, Christopher D. [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); di Mitri, Simone [Elettra–Sincrotrone Trieste, 34149 Basovizza, Trieste, Italy

    2016-05-01

    The coherent synchrotron radiation (CSR) of a high brightness electron beam traversing a series of dipoles, such as transport arcs, may result in phase space degradation. On one hand, the CSR can perturb electron transverse motion in dispersive regions along the beamline, causing emittance growth. On the other hand, the CSR effect on the longitudinal beam dynamics could result in microbunching gain enhancement. For transport arcs, several schemes have been proposed* to suppress the CSR-induced emittance growth. Similarly, several scenarios have been introduced** to suppress CSR-induced microbunching gain, which however mostly aim for linac-based machines. In this paper we try to provide sufficient conditions for suppression of CSR-induced microbunching gain along a transport arc, analogous to*. Several example lattices are presented, with the relevant microbunching analyses carried out by our semi-analytical Vlasov solver***. The simulation results show that lattices satisfying the proposed conditions indeed have microbunching gain suppressed. We expect this analysis can shed light on lattice design approach that could suppress the CSR-induced microbunching gain.

  1. Life gain in Italian smokers who quit.

    Science.gov (United States)

    Carrozzi, Laura; Falcone, Franco; Carreras, Giulia; Pistelli, Francesco; Gorini, Giuseppe; Martini, Andrea; Viegi, Giovanni

    2014-02-26

    This study aims to estimate the number of life years gained with quitting smoking in Italian smokers of both sexes, by number of cigarettes smoked per day (cig/day) and age at cessation. All-cause mortality tables by age, sex and smoking status were computed, based on Italian smoking data, and the survival curves of former and current smokers were compared. The more cig/day a man/woman smokes, and the younger his/her age of quitting smoking, the more years of life he/she gains with cessation. In fact, cessation at age 30, 40, 50, or 60 years gained, respectively, about 7, 7, 6, or 5, and 5, 5, 4, or 3 years of life, respectively, for men and women that smoked 10-19 cig/day. The gain in life years was higher for heavy smokers (9 years for >20 cig/day) and lower for light smokers (4 years for 1-9 cig/day). Consistently with prospective studies conducted worldwide, quitting smoking increases life expectancy regardless of age, gender and number of cig/day. The estimates of the number of years of life that could be gained by quitting smoking, when computed specifically for a single smoker, could be used by physicians and health professionals to promote a quit attempt.

  2. Intrinsic gain modulation and adaptive neural coding

    CERN Document Server

    Hong, Sungho; Fairhall, Adrienne

    2008-01-01

    In many cases, the computation of a neural system can be reduced to a receptive field, or a set of linear filters, and a thresholding function, or gain curve, which determines the firing probability; this is known as a linear/nonlinear model. In some forms of sensory adaptation, these linear filters and gain curve adjust very rapidly to changes in the variance of a randomly varying driving input. An apparently similar but previously unrelated issue is the observation of gain control by background noise in cortical neurons: the slope of the firing rate vs current (f-I) curve changes with the variance of background random input. Here, we show a direct correspondence between these two observations by relating variance-dependent changes in the gain of f-I curves to characteristics of the changing empirical linear/nonlinear model obtained by sampling. In the case that the underlying system is fixed, we derive relationships relating the change of the gain with respect to both mean and variance with the receptive fi...

  3. New night vision goggle gain definition

    Science.gov (United States)

    Podobedov, Vyacheslav B.; Eppeldauer, George P.; Larason, Thomas C.

    2015-05-01

    A new definition is proposed for the calibration of Night Vision Goggle (NVG) gains. This definition is based on the measurement of radiometric input and output quantities of the NVG. While the old definition used the "equivalent fL" which is a non SI traceable luminance unit, the new definition utilizes the radiance quantities that are traceable to the SI units through NIST standards. The new NVG gain matches the previous one as a result of the application of a correction coefficient originating from the conversion of the radiance to luminance units. The new definition was tested at the NIST Night Vision Calibration Facility and the measurement results were compared to the data obtained with a Hoffman Test Set Model ANV-126. Comparing the radiometric quantities of the Hoffman Test Set and those measured by the NIST transfer standard radiometer, indicates that the observed differences up to 15% were due to the calibration and experimental errors of the ANV-126 Test Set. In view of different spectral characteristics of luminophores that can be utilized in the NVG design, the simulation of the NVG output for gain measurement was performed. The NVG output was simulated with a sphere-based source using different LEDs and the measured gain was compared to that obtained with the ANV-126 internal luminance meter. The NVG gain uncertainty analysis was performed for the Type A, B, and C goggles.

  4. Seasonal Variations of Cell Site Diversity Gain

    Directory of Open Access Journals (Sweden)

    Sharmini Enoch

    2016-08-01

    Full Text Available The broadband fixed wireless access (BFWA systems operate in microwave frequencies. In this frequency range, the wave propagation is highly influenced by precipitation caused especially by rain. With the use of cell site diversity (CSD, the rain attenuation effects can be mitigated. When the signal level falls below a certain threshold the subscriber station switches to another base station within the coverage area. This paper aims at demonstrating the performance improvements obtained with the use of cell site diversity during various seasons for measurements carried out from HYREX rain gauge network in UK. The parameters traditionally used to quantify cell site diversity are CSD gain and diversity improvement. This paper analyzes the CSD gain achieved. The gain increases with increasing frequency and distance. The link performance is compared for various seasons and the results show that the maximum attenuation occurs during summer, while the least attenuation occurs during winter. Therefore, maximum gain of up to 22 dB occurs at 54 GHz frequency during winter. The second observation is that when the angular separation between the diversity sites is 180° separation there is maximum gain for all seasons.

  5. Combined Cycle Power Generation Employing Pressure Gain Combustion

    Energy Technology Data Exchange (ETDEWEB)

    Holley, Adam [United Technologies Corporation, East Hartford, CT (United States). Research Center

    2017-05-15

    The Phase I program assessed the potential benefit of applying pressure gain combustion (PGC) technology to a natural gas combined cycle power plant. A conceptual design of the PGC integrated gas turbine was generated which was simulated in a detailed system modeling tool. The PGC integrated system was 1.93% more efficient, produced 3.09% more power, and reduced COE by 0.58%. Since the PGC system used had the same fuel flow rate as the baseline system, it also reduced CO2 emissions by 3.09%. The PGC system did produce more NOx than standard systems, but even with the performanceand cost penalties associated with the cleanup system it is better in every measure. This technology benefits all of DOE’s stated program goals to improve plant efficiency, reduce CO2 production, and reduce COE.

  6. Slow-light enhanced gain in active photonic crystal waveguides

    CERN Document Server

    Ek, Sara; Chen, Yaohui; Semenova, Elizaveta; Yvind, Kresten; Mørk, Jesper

    2014-01-01

    Slow light is a fascinating physical effect, raising fundamental questions related to our understanding of light-matter interactions as well as offering new possibilities for photonic devices. From the first demonstrations of slow light propagation in ultra-cold atomic gasses, solid-state Ruby and photonic crystal structures, focus has shifted to applications, with slow light offering the ability to enhance and control light-matter interactions. The demonstration of tuneable delay lines, enhanced nonlinearities and spontaneous emission, enlarged spectral sensitivity and increased phase shifts illustrate the possibilities enabled by slow light propagation, with microwave photonics emerging as one of the promising applications. Here, we demonstrate that slow light can be used to control and increase the gain coefficient of an active semiconductor waveguide. The effect was theoretically predicted but not yet experimentally demonstrated. These results show a route towards realizing ultra-compact optical amplifier...

  7. Gain in Alzheimer care INstrument--a new scale to measure caregiving gains in dementia.

    Science.gov (United States)

    Yap, Philip; Luo, Nan; Ng, Wai Yee; Chionh, Hui Ling; Lim, June; Goh, Jenny

    2010-01-01

    To describe and validate a new scale, Gain in Alzheimer care Instrument (GAIN), and to measure gains in dementia caregiving. Items in GAIN were derived through a qualitative study of family carers of persons with dementia (PWD). Content validity of GAIN was established by a team of dementia care experts (geriatrician, nurse, and social worker) and through focus group discussion with 15 family carers. Consecutive carers of PWD were administered a questionnaire containing GAIN and other measures. Ambulatory dementia clinic of a tertiary hospital and the local Alzheimer's Association. Family carers of PWD. The psychometric properties of GAIN were examined, in particular, exploratory factor analysis and construct validity through correlation with extant measures; Positive Aspects of Caregiving (PAC), Dementia Management Strategies Scale (DMSS), and Zarit Burden Interview (ZBI). Two hundred thirty-eight English-speaking carers completed the survey. Mean age of carers was 50.1 year (standard deviation [SD] 10.1) and females (68.1%) and child carers (81.3%) comprised the majority. Mean GAIN score was 30.5 (SD 6.5). Internal consistency of GAIN by Cronbach's alpha was 0.89 and test-retest reliability (2 weeks) by Intraclass Correlation Coefficient was 0.70. GAIN correlated strongly with PAC (r = 0.68, df = 236, p management) (r = 0.42, df = 235, p 1 at 5.28, accounting for 52.8% of the variance. GAIN is a psychometrically reliable and valid instrument for measuring gains in dementia caregiving. It adds an important dimension to carer assessment in dementia.

  8. Capital Gains Taxation and House Price Fluctuations

    DEFF Research Database (Denmark)

    Fuest, Clemens; Nielsen, Søren Bo

    2004-01-01

    Recent years have seen large swings in house prices in many countries. Motivated by housing price variations, proposals for taxing capital gains on housing have repeatedly been put forth. The idea seems to be that such taxes would curb the redistribution occurring between those owning houses...... and those trying to get into the market for owner-occupied housing. Our paper shows that at least in simple settings, a tax on real capital gains on housing will only lead to even bigger price swings and will not be able to redistribute between people appearing on either side of the housing market.......Keywords: capital gains tax, housing market, price fluctuationsJEL-Classification: H23, H24, R 31.Addresses:...

  9. High fat diet causes rebound weight gain.

    Science.gov (United States)

    McNay, David E G; Speakman, John R

    2012-01-01

    Obesity is at epidemic proportions but treatment options remain limited. Treatment of obesity by calorie restriction (CR) despite having initial success often fails due to rebound weight gain. One possibility is that this reflects an increased body weight (BW) set-point. Indeed, high fat diets (HFD) reduce adult neurogenesis altering hypothalamic neuroarchitecture. However, it is uncertain if these changes are associated with weight rebound or if long-term weight management is associated with reversing this. Here we show that obese mice have an increased BW set-point and lowering this set-point is associated with rescuing hypothalamic remodelling. Treating obesity by CR using HFD causes weight loss, but not rescued remodelling resulting in rebound weight gain. However, treating obesity by CR using non-HFD causes weight loss, rescued remodelling and attenuates rebound weight gain. We propose that these phenomena may explain why successful short-term weight loss improves obesity in some people but not in others.

  10. Image formation using stimulated raman scattering gain

    Science.gov (United States)

    Bespalov, V. G.; Makarov, E. A.; Stasel'ko, D. I.

    2016-07-01

    Theoretical analysis of the spatial, noise, and energy characteristics of an amplifier has been performed in the mode of spectral and time selection using subnanosecond stimulated Raman Scattering gain of weak echo signals in crystalline active media that are known for high (up to 10-1 cm/MW) gain coefficients. The possibility to reach high gain values has been demonstrated for weak signals from objects at acceptable angular sizes of the field of vision of an amplifier. To provide a signal-to-noise ratio that exceeds unity over the entire field of vision, the number of photons at the input to an amplifier that is required has to exceed the number of its resolution elements. Accurate determination of the possibilities of recording of weak echo signals and quality of images of targets that are obtained using amplifiers under stimulated Raman Scattering requires additional special experiments.

  11. [Atypical antipsychotic-induced weight gain].

    Science.gov (United States)

    Godlewska, Beata R; Olajossy-Hilkesberger, Luiza; Marmurowska-Michałowska, Halina; Olajossy, Marcin; Landowski, Jerzy

    2006-01-01

    Introduction of a new group of antipsychotic drugs, called atypical because of the proprieties differing them from classical neuroleptics, gave hope for the beginning of a new era in treatment of psychoses, including schizophrenia. Different mechanisms of action not only resulted in a broader spectrum of action and high efficacy but also in a relative lack of extrapiramidal symptoms. However, atypical neuroleptics are not totally free from adverse effects. Symptoms such as sedation, metabolic changes and weight gain, often very quick and severe - present also in the case of classical drugs, but put to the background by extrapiramidal symptoms--have become prominent. Weight gain is important both from the clinical and subjective point of view--as associated with serious somatic consequences and as a source of enormous mental distress. These problems are addressed in this review, with the focus on weight gain associated with the use of specific atypical neuroleptics.

  12. High Gain Amplifier with Enhanced Cascoded Compensation

    Directory of Open Access Journals (Sweden)

    J. Lemus-Lopez

    2014-04-01

    Full Text Available A two-stage CMOS operational amplifier with both, gain-boosting and indirect current feedback frequency compensation performed by means of regulated cascode amplifiers, is presented. By using quasi-floating-gate transistors (QFGT the supply requirements, the number of capacitors and the size of the compensation capacitors respect to other Miller schemes are reduced. A prototype was fabricated using a 0.5 μm technology, resulting, for a load of 45 pF and supply voltage of 1.65 V, in open-loop-gain of 129 dB, 23 MHz of gain-bandwidth product, 60o phase margin, 675 μW power consumption and 1% settling time of 28 ns.

  13. Holistic control of ship noise emissions

    OpenAIRE

    Borelli Davide; Gaggero Tomaso; Rizzuto Enrico; Schenone Corrado

    2016-01-01

    The sustainability of anthropogenic activities at sea is recently gaining more and more attention. As regards shipping, emissions from ships into the environment of various nature (engine exhaust gases, anti-fouling paints leaching, ballast exchange, releases at sea of oil and other noxious liquid or solid cargoes, of sewage and of garbage) have been recognized as sources of pollution and therefore controlled and limited since a long time. The subject of noise emission...

  14. Effect of gain nonlinearity in semiconductor lasers

    DEFF Research Database (Denmark)

    Jensen, Niels H.; Christiansen, Peter Leth; Skovgaard, Ove

    1988-01-01

    Semiconductor lasers are modeled by single-mode rate equations with Langevin noise terms and the influence of nonlinear gain is investigated. For cw operation the probability distribution for the carrier number and the photon number in the laser cavity is obtained. The corresponding (2......+1)-dimensional Fokker-Planck equation is derived and integrated on an Amdahl VP1100 vector processor. Above threshold the resulting probability density agrees with the rate-equation predictions. The case of high-speed modulation is also considered. The nonlinear gain is found to stabilize the laser....

  15. The gain from improved market efficiency

    DEFF Research Database (Denmark)

    Ejrnæs, Mette; Persson, Karl Gunnar

    2010-01-01

    This article looks at the gains from improved market efficiency in long-distance grain trade in the second half of the nineteenth century, when violations of the law of one price were reduced due to improved information transmission. Two markets, a major export centre, Chicago, and a major importer...... after the information ‘regime' shifted from pre-telegraphic communication to a regime with swift transmission of information in an era that saw the development of a sophisticated commercial press and telegraphic communication. This article is the first attempt to actually measure the gains from improved...

  16. Microstrip antenna gain enhancement with metamaterial radome

    Science.gov (United States)

    Attachi, S.; Saleh, C.; Bouzouad, M.

    2017-01-01

    In this work, a high gain patch antenna using multilayer FSS radome is proposed for millimeter-wave applications. The antenna operating frequency is 43.5 GHz. The antenna/radome system consists of one, two, three, or four layers of metasurfaces placed in the near-field region of a microstrip patch antenna. The antenna/radome system gain is improved by 9 dBi compared to the patch antenna alone, and the radiation pattern half-power beamwidth is reduces to 20° in both E- and H-planes.

  17. The Biology of Intron Gain and Loss

    DEFF Research Database (Denmark)

    Jeffares, Daniel C; Mourier, Tobias; Penny, David

    2006-01-01

    Intron density in eukaryote genomes varies by more than three orders of magnitude, so there must have been extensive intron gain and/or intron loss during evolution. A favored and partial explanation for this range of intron densities has been that introns have accumulated stochastically in large...... eukaryote genomes during their evolution from an intron-poor ancestor. However, recent studies have shown that some eukaryotes lost many introns, whereas others accumulated and/or gained many introns. In this article, we discuss the growing evidence that these differences are subject to selection acting...... on introns depending on the biology of the organism and the gene involved....

  18. Large Engine Emission Reduction - LEER

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-10-15

    The target of the project LEER is to find the most cost-effective means of today to reduce exhaust gas emissions, particularly NO{sub x} and particulates, of power-plant and ship propulsion diesel engines. The methods are controlling of the combustion and exhaust gas after-treatment. As research methods, theoretical and literature studies as well as engine tests are used. Using the state of the art technology in the whole engine process from combustion control to after treatment is vital for keeping the product competitive in today's engine market. The project consists of two main tasks, Performance and Emission. The Performance task deals with controlling the combustion for optimising the trade-off between fuel consumption and pollutant formation, NO{sub x} in particular. The Emission task concentrates on improving the after treatment technology in particulate reduction, and understanding the particulate formation by gaining information of particulate nature and composition. (orig.)

  19. Sub-250nm room temperature optical gain from AlGaN materials with strong compositional fluctuations

    Science.gov (United States)

    Pecora, Emanuele; Zhang, Wei; Sun, Haiding; Nikiforov, A.; Yin, Jian; Paiella, Roberto; Moustakas, Theodore; Dal Negro, Luca

    2013-03-01

    Compact and portable deep-UV LEDs and laser sources are needed for a number of engineering applications including optical communications, gas sensing, biochemical agent detection, disinfection, biotechnology and medical diagnostics. We investigate the deep-UV optical emission and gain properties of AlxGa1-xN/AlyGa1-yN multiple quantum wells structure. These structures were grown by molecular-beam epitaxy on 6H-SiC substrates resulting in either homogeneous wells or various degrees of band-structure compositional fluctuations in the form of cluster-like features within the wells. We measured the TE-polarized amplified spontaneous emission in the sample with cluster-like features and quantified the optical absorption/gain coefficients and gain spectra by the Variable Stripe Length (VSL) technique under ultrafast optical pumping. We report blue-shift and narrowing of the emission, VSL traces, gain spectra, polarization studies, and the validity of the Schalow-Townes relation to demonstrate a maximum net modal gain of 120 cm-1 at 250 nm in the sample with strong compositional fluctuations. Moreover, we measure a very low gain threshold (15 μJ/cm2) . On the other hand, we found that samples with homogeneous quantum wells lead to absorption only. In addition, we report gain measurements in graded-index-separate-confined heterostructure (GRINSCH) designed to increase the device optical confinement factor.

  20. Loss or Mislocalization of Aquaporin-4 Affects Diffusion Properties and Intermediary Metabolism in Gray Matter of Mice.

    Science.gov (United States)

    Pavlin, T; Nagelhus, E A; Brekken, C; Eyjolfsson, E M; Thoren, A; Haraldseth, O; Sonnewald, U; Ottersen, O P; Håberg, A K

    2017-01-01

    The first aim of this study was to determine how complete or perivascular loss of aquaporin-4 (AQP4) water channels affects membrane permeability for water in the mouse brain grey matter in the steady state. Time-dependent diffusion magnetic resonance imaging was performed on global Aqp4 knock out (KO) and α-syntrophin (α-syn) KO mice, in the latter perivascular AQP4 are mislocalized, but still functioning. Control animals were corresponding wild type (WT) mice. By combining in vivo diffusion measurements with the effective medium theory and previously measured extra-cellular volume fractions, the effects of membrane permeability and extracellular volume fraction were uncoupled for Aqp4 and α-syn KO. The second aim was to assess the effect of α-syn KO on cortical intermediary metabolism combining in vivo [1-(13)C]glucose and [1,2-(13)C]acetate injection with ex vivo (13)C MR spectroscopy. Aqp4 KO increased the effective diffusion coefficient at long diffusion times by 5%, and a 14% decrease in membrane water permeability was estimated for Aqp4 KO compared with WT mice. α-syn KO did not affect the measured diffusion parameters. In the metabolic analyses, significantly lower amounts of [4-(13)C]glutamate and [4-(13)C]glutamine, and percent enrichment in [4-(13)C]glutamate were detected in the α-syn KO mice. [1,2-(13)C]acetate metabolism was unaffected in α-syn KO, but the contribution of astrocyte derived metabolites to GABA synthesis was significantly increased. Taken together, α-syn KO mice appeared to have decreased neuronal glucose metabolism, partly compensated for by utilization of astrocyte derived metabolites.

  1. Population genetic structure in Sabatieria (Nematoda) reveals intermediary gene flow and admixture between distant cold seeps from the Mediterranean Sea.

    Science.gov (United States)

    De Groote, Annelies; Hauquier, Freija; Vanreusel, Ann; Derycke, Sofie

    2017-07-01

    There is a general lack of information on the dispersal and genetic structuring for populations of small-sized deep-water taxa, including free-living nematodes which inhabit and dominate the seafloor sediments. This is also true for unique and scattered deep-sea habitats such as cold seeps. Given the limited dispersal capacity of marine nematodes, genetic differentiation between such geographically isolated habitat patches is expected to be high. Against this background, we examined genetic variation in both mitochondrial (COI) and nuclear (18S and 28S ribosomal) DNA markers of 333 individuals of the genus Sabatieria, abundantly present in reduced cold-seep sediments. Samples originated from four Eastern Mediterranean cold seeps, separated by hundreds of kilometers, and one seep in the Southeast Atlantic. Individuals from the Mediterranean and Atlantic were divided into two separate but closely-related species clades. Within the Eastern Mediterranean, all specimens belonged to a single species, but with a strong population genetic structure (ΦST = 0.149). The haplotype network of COI contained 19 haplotypes with the most abundant haplotype (52% of the specimens) shared between all four seeps. The number of private haplotypes was high (15), but the number of mutations between haplotypes was low (1-8). These results indicate intermediary gene flow among the Mediterranean Sabatieria populations with no evidence of long-term barriers to gene flow. The presence of shared haplotypes and multiple admixture events indicate that Sabatieria populations from disjunct cold seeps are not completely isolated, with gene flow most likely facilitated through water current transportation of individuals and/or eggs. Genetic structure and molecular diversity indices are comparable to those of epiphytic shallow-water marine nematodes, while no evidence of sympatric cryptic species was found for the cold-seep Sabatieria.

  2. Gain-clamping techniques in two-stage double-pass L-band EDFA

    Indian Academy of Sciences (India)

    S W harun; N Md Samsuri; H Ahmad

    2006-03-01

    Two designs of long-wavelength band erbium-doped fiber amplifier (L-band EDFA) for gain clamping in double-pass systems are demonstrated and compared. The first design is based on ring laser technique where a backward amplified spontaneous emission (ASE) from the second stage is routed into the feedback loop to create an oscillating laser for gain clamping. The gain is clamped at 18.6 dB from -40 to -8 dBm with a gain variation of less than ± 0.1 dB and a noise figure of less than 6 dB. Another scheme is based on partial reflection of ASE into the EDFA, which is demonstrated using a narrowband fiber Bragg grating. This scheme achieves a good gain clamping characteristic up to -12 dBm of input signal power with a gain variation of less than ± 0.3 dB from a clamped gain of 22 dB. The noise figure of a 1580 nm signal is maintained below 5 dB in this amplifier since this scheme is not based on lasing mechanism. The latter scheme is also expected to be free from the relaxation oscillation problem.

  3. Electron Cyclotron Emission Radiometer

    Science.gov (United States)

    Morales, Cristina

    2009-11-01

    There is much interest in studying plasmas that generate hot electrons. The goal of this project is to develop a wide band electron cyclotron radiometer to measure the non-Maxwellian rapid rises in electron temperature. These rapid increases in temperature will then be correlated to instabilities in the plasma. This project explores a type of noncontact temperature measurement. We will attempt to show the feasibility of electron cyclotron emissions to measure the Maryland Centrifugal Experiment's electron plasma temperature. The radiometer has been designed to have 100dB of gain and a sensitivity of 24mV/dB given by its logarithmic amplifier. If successful, this radiometer will be used as a diagnostic tool in later projects such as the proposed experiment studying magnetic reconnection using solar flux loops.

  4. Gain properties of germanate glasses singly doped with Tm3+ and Ho3+ ions

    Institute of Scientific and Technical Information of China (English)

    LIN Qiongfei; XIA Haiping; ZHANG Yuepin; WANG Jinhao; ZHANG Jianli; HE Sailong

    2009-01-01

    Two kinds of germanate glasses singly doped with the ion concentration of 2.0mol.%Tm3+ and 2.0mol.%Ho3+, respectively, were prepared. According to McCumber theory, the absorption and stimulated emission cross-sections corresponding to the 3H6←→3F4 transitions of Tm3+ (at 1.8 μm) and the 5I8←→5I7 transitions of Ho3+ (at 2.0 μm) were obtained, and respective gain cross-section spectra were also computed as a function of population inversion according to absorption and emission cross-sections and the ion concentrations. For Tm3+-doped germanate glasses, the maximum of the absorption, emission, and gain cross-sections reached a value higher than those reported for fluorozirconate, fluoride, and oxyfluoride glasses. For Ho3+-doped germanate glasses, the maximum of absorption, emission, and gain cross-sections reached a value higher than that reported for fluorozircoaluminate glasses. Hence, these Tm3+-doped and Ho3+-doped germanate glasses exhibited an advantage for application in mid-infrared lasers at about 1.8 and 2.0 μm wavelength.

  5. The V1 Population Gains Normalization

    NARCIS (Netherlands)

    Ganmor, Elad; Okun, Michael; Lampl, Ilan

    2009-01-01

    In this issue of Neuron, Busse et al. describe the population response to superimposed visual stimuli while Sit et al. examine the spatiotemporal evolution of cortical activation in response to small visual stimuli. Surprisingly, these two studies of V1 report that a single gain control model accoun

  6. Body weight gain and deep brain stimulation.

    Science.gov (United States)

    Rieu, Isabelle; Derost, Philippe; Ulla, Miguel; Marques, Ana; Debilly, Bérangère; De Chazeron, Ingrid; Chéreau, Isabelle; Lemaire, Jean Jacques; Boirie, Yves; Llorca, Pierre Michel; Durif, Franck

    2011-11-15

    Deep brain stimulation (DBS) is a neurosurgical technique that has now been available for some 25 years. It is used in the treatment of various motor disorders, e.g. Parkinson's disease (PD), essential tremor and dystonia, and neuropsychiatric illnesses, e.g. obsessive-compulsive disorder and Tourette syndrome. The surgical targets of DBS include the thalamic ventralis intermedius nucleus (Vim), the globus pallidus internus (GPi) and more recently the subthalamic nucleus (STN), currently considered as the reference target in the treatment of PD. In the last ten years, most studies in PD patients have described a rapid and marked weight gain in the months following DBS of the STN. This weight gain sometimes induces obesity and can have metabolic repercussions. The physiopathological mechanisms responsible for the weight gain are multifactorial (changes in energy metabolism and eating behaviour, reduction of motor complications, etc.). This review reports current knowledge concerning weight changes in patients treated by DBS with different surgical targets. It also describes the mechanisms responsible for weight gain and the health outcome for the patients.

  7. Leaving home for college and gaining independence

    NARCIS (Netherlands)

    Mulder, C.H.; Clark, W.A.V.

    2002-01-01

    As more and more young US adults attend college it has become an increasingly important filter in the process of becoming an independent household. Now for a large number of young adults living in the USA, living away at college is a first step in the process of gaining residential and economic

  8. Causes and Consequences of Interdialytic weight gain

    NARCIS (Netherlands)

    Ipema, Karin J. R.; Kuipers, Johanna; Westerhuis, Ralf; Gaillard, Carlo A. J. M.; Schans, van der Cees P.; Krijnen, Wim P.; Franssen, Casper F. M.

    2016-01-01

    Background/Aims: Higher interdialytic weight gain (IDWG) is associated with higher predialysis blood pressure and increased mortality. IDWG is also increasingly being recognized as an indicator of nutritional status. We studied in detail the associations of various patient factors and nutritional pa

  9. Organic Causes of Weight Gain and Obesity

    Science.gov (United States)

    ... 18-21yrs. Healthy Living Healthy Living Healthy Living Nutrition Fitness Sports Oral Health Emotional Wellness Growing Healthy Sleep Safety & ... Tobacco Treatments Injuries & Emergencies Vaccine Preventable Diseases ... Children > Health Issues > Conditions > Obesity > Organic Causes of Weight Gain and Obesity Health ...

  10. Two scale high gain adaptive control

    NARCIS (Netherlands)

    Polderman, Jan W.; Mareels, I.M.Y.; Mareels, Iven

    2004-01-01

    Simple adaptive controllers based on high gain output feedback suffer a lack of robustness with respect to bounded disturbances. Existing modifications achieve boundedness of all solutions but introduce solutions that, even in the absence of disturbances, do not achieve regulation. In this paper a

  11. 75 FR 63763 - Program Integrity: Gainful Employment

    Science.gov (United States)

    2010-10-18

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF EDUCATION 34 CFR Part 668 RIN 1840-AD04 Program Integrity: Gainful Employment AGENCY: Office of Postsecondary Education, Department of Education. ACTION: Notice of public meeting sessions. SUMMARY: The Secretary...

  12. Shanghai Performing Arts Fair Gaining Global Popularity

    Institute of Scientific and Technical Information of China (English)

    TianZui; ZuZhongren

    2003-01-01

    China Shanghai International Arts Festival Performing Arts Fair is gaining popularity. In two months after the dates of the fair were announced, all the 120 booths were booked out, and for the first time in the event's four-year history, participants had to scramble to get in. When the trade fair opened, about 40 organizations were shut out.

  13. Speech perception of noise with binary gains

    DEFF Research Database (Denmark)

    Wang, DeLiang; Kjems, Ulrik; Pedersen, Michael Syskind

    2008-01-01

    For a given mixture of speech and noise, an ideal binary time-frequency mask is constructed by comparing speech energy and noise energy within local time-frequency units. It is observed that listeners achieve nearly perfect speech recognition from gated noise with binary gains prescribed...

  14. How Subsidiaries Gain Power in Multinational Corporations

    DEFF Research Database (Denmark)

    Mudambi, Ram; Pedersen, Torben; Andersson, Ulf

    2014-01-01

    This study focuses on how power is gained within large organizations, such as the intra-organizational network of MNCs. Drawing on resource dependence literature, this study develops and empirically tests a set of hypotheses aimed at explaining the multifaceted nature of power and decision making...

  15. Weight Gain Through Self-Control Procedures

    Science.gov (United States)

    Gulanick, Nancy; And Others

    1975-01-01

    Underweight subjects were assigned to either a self-reinforcement condition, a self-punishment condition, or to a discussion/reflection control condition. The subjects received one treatment session per week over a five-week period. After treatment, the self-reinforcement groups gained significantly more pounds (kilograms) than either of the other…

  16. The child with poor weight gain

    African Journals Online (AJOL)

    2007-04-11

    Apr 11, 2007 ... competence to be able to judge whether there is a problem, to identify babies ... The only objective way of assessing a child's weight gain is to take ... His main interests lie in the fields of gastroenterology and nutrition. 176 .... such as renal tubular disorders or defects ... exist in respect of the energy, protein,.

  17. Method and system for edge cladding of laser gain media

    Science.gov (United States)

    Bayramian, Andrew James; Caird, John Allyn; Schaffers, Kathleen Irene

    2014-03-25

    A gain medium operable to amplify light at a gain wavelength and having reduced transverse ASE includes an input surface and an output surface opposing the input surface. The gain medium also includes a central region including gain material and extending between the input surface and the output surface along a longitudinal optical axis of the gain medium. The gain medium further includes an edge cladding region surrounding the central region and extending between the input surface and the output surface along the longitudinal optical axis of the gain medium. The edge cladding region includes the gain material and a dopant operable to absorb light at the gain wavelength.

  18. Efficient light amplification in low gain materials due to a photonic band edge effect.

    Science.gov (United States)

    Ondič, L; Pelant, I

    2012-03-26

    One of the possibilities of increasing optical gain of a light emitting source is by embedding it into a photonic crystal (PhC). If the properties of the PhC are tuned so that the emission wavelength of the light source with gain falls close to the photonic band edge of the PhC, then due to low group velocity of the light modes near the band edge caused by many multiple reflections of light on the photonic structure, the stimulated emission can be significantly enhanced. Here, we perform simulation of the photonic band edge effect on the light intensity of spectrally broad source interacting with a diamond PhC with low optical gain. We show that even for the case of low gain, up to 10-fold increase of light intensity output can be obtained for the two-dimensional PhC consisting of only 19 periodic layers of infinitely high diamond rods ordered into a square lattice. Moreover, considering the experimentally feasible structure composed of diamond rods of finite height - PhC slab - we show that the gain enhancement, even if reduced compared to the ideal case of infinite rods, still remains relatively high. For this particular structure, we show that up to 3.5-fold enhancement of light intensity can be achieved.

  19. How to gain gain a reference book on triodes in audio pre-amps

    CERN Document Server

    Vogel, Burkhard

    2013-01-01

    The 34 chapters of the 2nd edition of How to Gain Gain give a detailed insight into a collection (54) of the most common gain producing, constant current generating possibilities, and electronic noise creation of triodes for audio pre-amplifier purposes. These chapters also offer complete sets of formulae to calculate gain, frequency and phase responses, and signal-to-noise ratios of certain building blocks built-up with this type of vacuum valve (tube). In all cases detailed derivations of the gain formulae are also presented. All what is needed are the data sheet valve characteristic figures of the triode's mutual conductance, the gain factor and the internal plate (anode) resistance. To calculate frequency and phase responses of gain stages the different data sheet based input and output capacitances have to be taken into account too. To calculate transfer functions and signal-to-noise ratios for any kind of triode driven gain stage, including all its bias setting, frequency, phase, and electronic noise in...

  20. LPV gain-scheduled control of SCR aftertreatment systems

    Science.gov (United States)

    Meisami-Azad, Mona; Mohammadpour, Javad; Grigoriadis, Karolos M.; Harold, Michael P.; Franchek, Matthew A.

    2012-01-01

    Hydrocarbons, carbon monoxide and some of other polluting emissions produced by diesel engines are usually lower than those produced by gasoline engines. While great strides have been made in the exhaust aftertreatment of vehicular pollutants, the elimination of nitrogen oxide (NO x ) from diesel vehicles is still a challenge. The primary reason is that diesel combustion is a fuel-lean process, and hence there is significant unreacted oxygen in the exhaust. Selective catalytic reduction (SCR) is a well-developed technology for power plants and has been recently employed for reducing NO x emissions from automotive sources and in particular, heavy-duty diesel engines. In this article, we develop a linear parameter-varying (LPV) feedforward/feedback control design method for the SCR aftertreatment system to decrease NO x emissions while keeping ammonia slippage to a desired low level downstream the catalyst. The performance of the closed-loop system obtained from the interconnection of the SCR system and the output feedback LPV control strategy is then compared with other control design methods including sliding mode, and observer-based static state-feedback parameter-varying control. To reduce the computational complexity involved in the control design process, the number of LPV parameters in the developed quasi-LPV (qLPV) model is reduced by applying the principal component analysis technique. An LPV feedback/feedforward controller is then designed for the qLPV model with reduced number of scheduling parameters. The designed full-order controller is further simplified to a first-order transfer function with a parameter-varying gain and pole. Finally, simulation results using both a low-order model and a high-fidelity and high-order model of SCR reactions in GT-POWER interfaced with MATLAB/SIMULINK illustrate the high NO x conversion efficiency of the closed-loop SCR system using the proposed parameter-varying control law.

  1. A novel control method for on-off gain and gain tilt of fiber Raman amplifiers

    Institute of Scientific and Technical Information of China (English)

    Xue Feng(冯雪); Wei Zhang(张巍); Xiaoming Liu(刘小明); Jiangde Peng(彭江得)

    2004-01-01

    Considering spectrum tilt due to signal-to-signal Raman scattering (SSRS) in backward distributed fiber Raman amplifiers (B-DFRA), an inverse tilted on-off gain profile is adopted to achieve flat net gain. A simple approximate linear relationship of pump power at each wavelength versus on-off gain level and tilt was derived numerically and experimentally so that a novel control method was established. Since there are only 3 pre-determinable constants required for individual pump wave, it is easy to be realized. As an example, maximum errors less than 0.2 and 0.4 dB respectively for average gain and gain tilt were achieved over C+L band in 100-km back-pumped standard single-mode fiber (SMF) experimentally.

  2. VISA IB Ultra-High Bandwidth, High Gain SASE FEL

    CERN Document Server

    Andonian, Gerard; Murokh, Alex; Pellegrini, Claudio; Reiche, Sven; Rosenzweig, J B; Travish, Gil

    2004-01-01

    The results of a high energy-spread SASE FEL experiment, the intermediary experiment linking the VISA I and VISA II projects, are presented. A highly chirped beam (~1.7%) was transported without correction of longitudinal aberrations in the ATF dogleg, and injected into the VISA undulator. The output FEL radiation displayed an uncharacteristicly large bandwidth (~11%) with extremely stable lasing and measured energy of about 2 microJoules. Start-to-end simulations reproduce key features of the measured results and provide an insight into the mechanisms giving rise to such a high bandwidth. These analyses are described as they relate to important considerations for the VISA II experiment.

  3. Characteristics measurement of gain and refractive index of traveling-wave semiconductor optical amplifier

    Institute of Scientific and Technical Information of China (English)

    MIAO Qing-yuan; Huang De-xiu; WANG Tao; KONG Xiao-jian; KE Chang-jian

    2005-01-01

    A novel method to measure the gain and refractive index characteristics of traveling-wave semiconductor optical amplifier(TMA) is presented.In-out fiber ends of TWA are used to construct an external cavity resonator to produce big ripple on amplified spontaneous emission(ASE) spectrum.By this means,Hakki-Paoli method is adopted to obtain the gain spectra of TWA over a wide spectral range.From measured longitudinal mode spacing and peak wavelength shift due to increased bias current,we further calculate the effective refractive index and the refractive index change.Special feature of refractive index change above lasing threshold is revealed and explained.

  4. Astronomers Gain Clues About Fundamental Physics

    Science.gov (United States)

    2005-12-01

    An international team of astronomers has looked at something very big -- a distant galaxy -- to study the behavior of things very small -- atoms and molecules -- to gain vital clues about the fundamental nature of our entire Universe. The team used the National Science Foundation's Robert C. Byrd Green Bank Telescope (GBT) to test whether the laws of nature have changed over vast spans of cosmic time. The Green Bank Telescope The Robert C. Byrd Green Bank Telescope CREDIT: NRAO/AUI/NSF (Click on image for GBT gallery) "The fundamental constants of physics are expected to remain fixed across space and time; that's why they're called constants! Now, however, new theoretical models for the basic structure of matter indicate that they may change. We're testing these predictions." said Nissim Kanekar, an astronomer at the National Radio Astronomy Observatory (NRAO), in Socorro, New Mexico. So far, the scientists' measurements show no change in the constants. "We've put the most stringent limits yet on some changes in these constants, but that's not the end of the story," said Christopher Carilli, another NRAO astronomer. "This is the exciting frontier where astronomy meets particle physics," Carilli explained. The research can help answer fundamental questions about whether the basic components of matter are tiny particles or tiny vibrating strings, how many dimensions the Universe has, and the nature of "dark energy." The astronomers were looking for changes in two quantities: the ratio of the masses of the electron and the proton, and a number physicists call the fine structure constant, a combination of the electron charge, the speed of light and the Planck constant. These values, considered fundamental physical constants, once were "taken as time independent, with values given once and forever" said German particle physicist Christof Wetterich. However, Wetterich explained, "the viewpoint of modern particle theory has changed in recent years," with ideas such as

  5. Valve timing: its effect on emissions and fuel economy

    Energy Technology Data Exchange (ETDEWEB)

    Bechtold, R.L.; Marshall, W.F.

    1977-08-01

    The effects of valve timing on exhaust emissions and fuel consumption were investigated experimentally. Emission control through the use of varied valve timing compared to conventional emissions control hardware was documented along with the effects of valve timing on emissions. Fuel consumption trends with changed valve timing were determined. The engine design of the test vehicle allowed independent adjustment of intake and exhaust valve timing. Emissions and fuel consumption were determined for steady-state speeds of 20 through 60 mph in 10 mph increments. A wide variety of intake and exhaust valve timing combinations were tested and the results compared to those of the production vehicle before modification. These results showed that valve timing has a significant effect on oxides of nitrogen emissions, but additional emissions control hardware is necessary to meet current and proposed emission regulations. Compared to emission control, varied valve timing holds more promise for reduced fuel consumption through a gain in cycle efficiency at various speeds.

  6. The role of intermediaries in delivering an occupational health and safety programme designed for small business - a case study of an insurance incentive programme in the agriculture sector

    DEFF Research Database (Denmark)

    Olsen, Kirsten Bendix; Hasle, Peter

    2015-01-01

    Intermediaries play an important role in disseminating national Occupational Health and Safety (OHS) programmes to small businesses but not much is known about the factors that influence their role. The aim of this paper is to elucidate the factors that influence intermediaries’ contribution...... to the transformation and dissemination of a national OHS programme for small business that built on an Insurance incentive scheme – the New Zealand Workplace Safety Discount scheme. It is a case study of this scheme implementation in the agriculture sector. Data was collected from scheme documentation and semi...

  7. Weight gain, physical activity and dietary changes during the seven ...

    African Journals Online (AJOL)

    2011-06-06

    Jun 6, 2011 ... Keywords: Malawi, overweight, obesity, university, weight gain. Weight gain, physical ... The authors sought to assess weight gain, physical activity and ..... 47.1% of children under the age of five years (40.7% in urban, and.

  8. Gain Variation with Raman Amplifier Parameters and Its Restoration

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    We demonstrate that gain profile of a distributed Raman amplifier is sensitive to its parameter variation, such as loss/gain coefficients change or partial pump failure. Gain flatness can be restored by adjusting power of pump lasers.

  9. Feedback Loop Gains and Feedback Behavior (1996)

    DEFF Research Database (Denmark)

    Kampmann, Christian Erik

    2012-01-01

    Linking feedback loops and system behavior is part of the foundation of system dynamics, yet the lack of formal tools has so far prevented a systematic application of the concept, except for very simple systems. Having such tools at their disposal would be a great help to analysts in understanding...... large, complicated simulation models. The paper applies tools from graph theory formally linking individual feedback loop strengths to the system eigenvalues. The significance of a link or a loop gain and an eigenvalue can be expressed in the eigenvalue elasticity, i.e., the relative change...... of an eigenvalue resulting from a relative change in the gain. The elasticities of individual links and loops may be found through simple matrix operations on the linearized system. Even though the number of feedback loops can grow rapidly with system size, reaching astronomical proportions even for modest systems...

  10. Pole placement with constant gain output feedback

    Science.gov (United States)

    Sridhar, B.; Lindorff, D. P.

    1972-01-01

    Given a linear time invariant multivariable system with m inputs and p outputs, it was shown that p closed loop poles of the system can be preassigned arbitrarily using constant gain output feedback provided (A circumflex, B circumflex) is controllable. These data show that if (A circumflex, B circumflex, C circumflex) is controllable and observable, and Rank B circumflex = m, Rank C circumflex = p, then max (m,p) poles of the system can be assigned arbitarily using constant gain output feedback. Further, it is shown that in some cases more than max (m,p) poles can be arbitrarily assigned. A least square design technique is outlined to approximate the desired pole locations when it is not possible to place all the poles.

  11. Brain Gain am Beispiel Österreich

    Directory of Open Access Journals (Sweden)

    Aschbacher Christine

    2016-06-01

    Full Text Available BrainGain is a common trend within the last ten years in Europe and all-over the world. Managers, key players and scientists are allowed to choose wherever they want to work in the world. As there is a lack of qualified individuals for companies and universities, BrainGain has become a necessity, and mostly – the higher educated individuals are moving away according to a better offer elsewhere in the world. Therefore, a lot of expats are moving around with their families. Many times, the lack of integration at the current place, country or city, is the critical success factor for staying or leaving. Furthermore, if the family does not feel happy in the current location, then the manager or scientist will move away or return home and the investment will be lost.

  12. Directionality switchable gain stabilized linear repeater

    Science.gov (United States)

    Ota, Takayuki; Ohmachi, Tadashi; Aida, Kazuo

    2004-10-01

    We propose a new approach to realize a bidirectional linear repeater suitable for future optical internet networks and fault location in repeater chain with OTDR. The proposed approach is the linear repeater of simple configuration whose directionality is rearranged dynamically by electrical control signal. The repeater is composed of a magneto-optical switch, a circulator, a dynamically gain stabilized unidirectional EDFA, and control circuits. The repeater directionality is rearranged as fast as 0.1ms by an electrical control pulse. It is experimentally confirmed that OTDR with the directionality switchable repeater is feasible for repeater chain. The detailed design and performance of the repeater are also discussed, including the multi-pass interference (MPI) which may arise in the proposed repeater, the effect of the MPI on SNR degradation of the repeater chain and the feed-forward EDFA gain control circuit.

  13. The Gains from Improved Market Efficiency

    DEFF Research Database (Denmark)

    Persson, Karl Gunnar; Ejrnæs, Mette

    faster, violations of the law of one price become smaller and hence less persistent. There were also significant gains from improved market efficiency but that improvement took place after the information ‘regime’ shifted from pre-telegraphic communication to a regime with swift transmission...... of information in an era which developed a sophisticated commercial press and telegraphic communication. Improved market efficiency probably stimulated trade more than falling transport costs......This paper looks at the gains from improved market efficiency in long-distance grain trade in the second half of the 19th century when violations of the law of one price were reduced due to improved information transmission. Two markets, a major export centre, Chicago, and a major importer...

  14. Sabbatical leave: who gains and how much?

    Science.gov (United States)

    Davidson, Oranit B; Eden, Dov; Westman, Mina; Cohen-Charash, Yochi; Hammer, Leslie B; Kluger, Avraham N; Krausz, Moshe; Maslach, Christina; O'Driscoll, Michael; Perrewé, Pamela L; Quick, James Campbell; Rosenblatt, Zehava; Spector, Paul E

    2010-09-01

    A rigorous quasi-experiment tested the ameliorative effects of a sabbatical leave, a special case of respite from routine work. We hypothesized that (a) respite increases resource level and well-being and (b) individual differences and respite features moderate respite effects. A sample of 129 faculty members on sabbatical and 129 matched controls completed measures of resource gain, resource loss, and well-being before, during, and after the sabbatical. Among the sabbatees, resource loss declined and resource gain and well-being rose during the sabbatical. The comparison group showed no change. Moderation analysis revealed that those who reported higher respite self-efficacy and greater control, were more detached, had a more positive sabbatical experience, and spent their sabbatical outside their home country enjoyed more enhanced well-being than others.

  15. Contrast Gain Control Model Fits Masking Data

    Science.gov (United States)

    Watson, Andrew B.; Solomon, Joshua A.; Null, Cynthia H. (Technical Monitor)

    1994-01-01

    We studied the fit of a contrast gain control model to data of Foley (JOSA 1994), consisting of thresholds for a Gabor patch masked by gratings of various orientations, or by compounds of two orientations. Our general model includes models of Foley and Teo & Heeger (IEEE 1994). Our specific model used a bank of Gabor filters with octave bandwidths at 8 orientations. Excitatory and inhibitory nonlinearities were power functions with exponents of 2.4 and 2. Inhibitory pooling was broad in orientation, but narrow in spatial frequency and space. Minkowski pooling used an exponent of 4. All of the data for observer KMF were well fit by the model. We have developed a contrast gain control model that fits masking data. Unlike Foley's, our model accepts images as inputs. Unlike Teo & Heeger's, our model did not require multiple channels for different dynamic ranges.

  16. The Gains from Improved Market Efficiency

    DEFF Research Database (Denmark)

    Persson, Karl Gunnar; Ejrnæs, Mette

    This paper looks at the gains from improved market efficiency in long-distance grain trade in the second half of the 19th century when violations of the law of one price were reduced due to improved information transmission. Two markets, a major export centre, Chicago, and a major importer......, Liverpool, are analyzed. We show that there was a law of one price equilibrium throughout the period but that markets displayed spells of demand- or supply-constrained trade when the law of one price was violated. Over time adjustments back to equilibrium, as measured by the half-life of a shock, become...... faster, violations of the law of one price become smaller and hence less persistent. There were also significant gains from improved market efficiency but that improvement took place after the information ‘regime’ shifted from pre-telegraphic communication to a regime with swift transmission...

  17. Comparison of experimental and theoretical gain-current relations in GaInP quantum well lasers

    Energy Technology Data Exchange (ETDEWEB)

    Smowton, P.M.; Chow, W.W.; Blood, P.

    2000-01-10

    The authors compare the results of a microscopic laser theory with gain and recombination currents obtained from experimental spontaneous emission spectra. The calculated absorption spectrum is first matched to that measured on a laser, ensuring that the quasi-Fermi levels for the calculation and the experiment (spontaneous emission and gain) are directly related. This allows one to determine the inhomogeneous broadening in their experimental samples. The only other inputs to the theory are literature values of the bulk material parameter. The authors then estimate the non-radiative recombination current associated with the well and wave-guide core from a comparison of measured and calculated recombination currents.

  18. Optical antenna gain. II - Receiving antennas

    Science.gov (United States)

    Degnan, J. J.; Klein, B. J.

    1974-01-01

    Expressions are developed for the gain of a centrally obscured, circular optical antenna used as the collecting and focusing optics in a laser receiver, involving losses due to (1) incoming light blockage by central obscuration, (2) energy spillover at the detector, and (3) the effect of local oscillator distribution in the case of heterodyne or homodyne detection. Numerical results are presented for direct detection and for three types of local oscillator distribution (uniform, Gaussian, and matched).

  19. Autonomous Exploration Using an Information Gain Metric

    Science.gov (United States)

    2016-03-01

    quantified by computing the entropy of the robot’s a posteriori pose estimate. The robot’s pose history along its trajectory is captured by the mapping...man-portable robot system. The robot was equipped with additional computing hardware to increase the capabilities of the platform. Similarly, the...Laboratory Autonomous Exploration Using an Information Gain Metric by Nicholas C Fung, Jason M Gregory, and John G Rogers Computational and

  20. Pregnancy weight gain and breast cancer risk

    Directory of Open Access Journals (Sweden)

    Hemminki Elina

    2004-10-01

    Full Text Available Abstract Background Elevated pregnancy estrogen levels are associated with increased risk of developing breast cancer in mothers. We studied whether pregnancy weight gain that has been linked to high circulating estrogen levels, affects a mother's breast cancer risk. Methods Our cohort consisted of women who were pregnant between 1954–1963 in Helsinki, Finland, 2,089 of which were eligible for the study. Pregnancy data were collected from patient records of maternity centers. 123 subsequent breast cancer cases were identified through a record linkage to the Finnish Cancer Registry, and the mean age at diagnosis was 56 years (range 35 – 74. A sample of 979 women (123 cases, 856 controls from the cohort was linked to the Hospital Inpatient Registry to obtain information on the women's stay in hospitals. Results Mothers in the upper tertile of pregnancy weight gain (>15 kg had a 1.62-fold (95% CI 1.03–2.53 higher breast cancer risk than mothers who gained the recommended amount (the middle tertile, mean: 12.9 kg, range 11–15 kg, after adjusting for mother's age at menarche, age at first birth, age at index pregnancy, parity at the index birth, and body mass index (BMI before the index pregnancy. In a separate nested case-control study (n = 65 cases and 431 controls, adjustment for BMI at the time of breast cancer diagnosis did not modify the findings. Conclusions Our study suggests that high pregnancy weight gain increases later breast cancer risk, independently from body weight at the time of diagnosis.

  1. Gaining Customers` Trust In Online Stores

    OpenAIRE

    Anamaria Severin-Humelnicu

    2010-01-01

    Trust is very important in running businesses on the Internet. It plays a significant role in the actions a consumer undertakes in the online purchase process. An online store will never reach the desired level of sales until it gains the trust of its consumers. Building confidence is the key of succes in electronic commerce. Therefore, any online retailer should strive to achieve this goal

  2. Loss/gain-induced ultrathin antireflection coatings

    OpenAIRE

    Jie Luo; Sucheng Li; Bo Hou; Yun Lai

    2016-01-01

    Tradional antireflection coatings composed of dielectric layers usually require the thickness to be larger than quarter wavelength. Here, we demonstrate that materials with permittivity or permeability dominated by imaginary parts, i.e. lossy or gain media, can realize non-resonant antireflection coatings in deep sub-wavelength scale. Interestingly, while the reflected waves are eliminated as in traditional dielectric antireflection coatings, the transmitted waves can be enhanced or reduced, ...

  3. ROMANIA'S EU ACCESSION. GAINS AND LOSSES (I

    Directory of Open Access Journals (Sweden)

    Caba Stefan

    2012-07-01

    Full Text Available EU accession has brought, as expected, many changes in economic, social and cultural domains. An important chapter is the trade dynamics and how this dynamic has been modified over time by changes in the legal status of Romania's relations with certain trading partners. In this paper we present data on trade with countries with which Romania has concluded trade agreements before accession. Data presentation and analysis continues in "Romania's EU accession. Gains and losses (II".

  4. Optical antenna gain. III - The effect of secondary element support struts on transmitter gain

    Science.gov (United States)

    Klein, B. J.; Degnan, J. J.

    1976-01-01

    The effect of a secondary-element spider support structure on optical antenna transmitter gain is analyzed. An expression describing the influence of the struts on the axial gain, in both the near and far fields, is derived as a function of the number of struts and their width. It is found that, for typical systems, the struts degrade the on-axis gain by less than 0.4 dB, and the first side-lobe level is not increased significantly. Contour plots have also been included to show the symmetry of the far-field distributions for three- and four-support members.

  5. Optical antenna gain. 3: The effect of secondary element support struts on transmitter gain.

    Science.gov (United States)

    Klein, B J; Degnan, J J

    1976-04-01

    The effect of a secondary element spider support structure on optical antenna transmitter gain is analyzed. An expression describing the influence of the struts on the axial gain, in both the near and far fields, is derived as a function of the number of struts and their width. It is found that, for typical systems, the struts degrade the on-axis gain by less than 0.4 dB, and the first side-lobe level is not increased significantly. Contour plots have also been included to show the symmetry of the far-field distributions for three and four support members.

  6. Optical antenna gain. 2: receiving antennas.

    Science.gov (United States)

    Degnan, J J; Klein, B J

    1974-10-01

    Expressions are derived for the gain of a centrally obscured, circular optical antenna when used as the collecting and focusing optics in a laser receiver which include losses due to (1) blockage of the incoming light by the central obscuration, (2) the spillover of energy at the detector, and (3) the effect of local oscillator distribution in the case of heterodyne or homodyne detection. Numerical results are presented for direct detection and for three types of local oscillator distributions (uniform, Gaussian, and matched) in the case of heterodyne or homodyne detection. The results are presented in several graphs that allow the rapid evaluation of receiver gain for an arbitrary set of telescope and detector parameters. It is found that, for uniform illumination by the LO, the optimum SNR is obtained when the detector radius is approximately 0.74 times the Airy disk radius. The use of an optimized Gaussian (spot size = 0.46 times the Airy disk radius) improves the receiver gain by less than 1 dB. Theuse results are insensitive to the size of the central obscuration.

  7. Sensor management based on fisher information gain

    Institute of Scientific and Technical Information of China (English)

    Tian Kangsheng; Zhu Guangxi

    2006-01-01

    Multi-sensor system is becoming increasingly important in a variety of military and civilian applications. In general, single sensor system can only provide partial information about environment while multi-sensor system provides a synergistic effect, which improves the quality and availability of information. Data fusion techniques can effectively combine this environmental information from similar and/or dissimilar sensors. Sensor management, aiming at improving data fusion performance by controlling sensor behavior, plays an important role in a data fusion process. This paper presents a method using fisher information gain based sensor effectiveness metric for sensor assignment in multi-sensor and multi-target tracking applications. The fisher information gain is computed for every sensor-target pairing on each scan. The advantage for this metric over other ones is that the fisher information gain for the target obtained by multi-sensors is equal to the sum of ones obtained by the individual sensor, so standard transportation problem formulation can be used to solve this problem without importing the concept of pseudo sensor. The simulation results show the effectiveness of the method.

  8. Raman gains of ADP and KDP crystals

    Institute of Scientific and Technical Information of China (English)

    周海亮; 柴向旭; 张清华; 王波; 许心光; 王正平; 孙洵; 张芳; 张立松; 刘宝

    2015-01-01

    In this paper, the Raman gain coefficients of ammonium dihydrogen phosphate (ADP) and potassium dihydrogen phosphate (KDP) crystals are measured. By using a pump source of a 30-ps, 532-nm laser, the gain coefficients of ADP and KDP are 1.22 cm/GW, and 0.91 cm/GW, respectively. While for a 20-ps, 355-nm pump laser, the gain coefficients of these two crystals are similar, which are 1.95 cm/GW for ADP and 1.86 for KDP. The present results indicate that for ultra-violet frequency conversion, the problem of stimulated Raman scattering for ADP crystal will not be more serious than that for KDP crystal. Considering other advantages such the larger nonlinear optical coefficient, higher laser damage threshold, and lower noncritical phase-matching temperature, it can be anticipated that ADP will be a powerful competitor to KDP in large aperture, high energy third-harmonic generation or fourth-harmonic generation applications.

  9. Loss/gain-induced ultrathin antireflection coatings.

    Science.gov (United States)

    Luo, Jie; Li, Sucheng; Hou, Bo; Lai, Yun

    2016-06-28

    Tradional antireflection coatings composed of dielectric layers usually require the thickness to be larger than quarter wavelength. Here, we demonstrate that materials with permittivity or permeability dominated by imaginary parts, i.e. lossy or gain media, can realize non-resonant antireflection coatings in deep sub-wavelength scale. Interestingly, while the reflected waves are eliminated as in traditional dielectric antireflection coatings, the transmitted waves can be enhanced or reduced, depending on whether gain or lossy media are applied, respectively. We provide a unified theory for the design of such ultrathin antireflection coatings, showing that under different polarizations and incident angles, different types of ultrathin coatings should be applied. Especially, under transverse magnetic polarization, the requirement shows a switch between gain and lossy media at Brewster angle. As a proof of principle, by using conductive films as a special type of lossy antireflection coatings, we experimentally demonstrate the suppression of Fabry-Pérot resonances in a broad frequency range for microwaves. This valuable functionality can be applied to remove undesired resonant effects, such as the frequency-dependent side lobes induced by resonances in dielectric coverings of antennas. Our work provides a guide for the design of ultrathin antireflection coatings as well as their applications in broadband reflectionless devices.

  10. Multifold Laser Resonator for Annular Gain Media.

    Science.gov (United States)

    Duncan, Arlene

    Available from UMI in association with The British Library. A pair of spherical mirrors enclosing an off-axis beam in a hyperboloidal ray trajectory describes a Herriott Cell. Placed inside a linear Fabry Perot resonator, a multifold laser resonator is formed. By considering this resonator when coupled to a coaxial, annular geometry, RF discharge excited CO_2 gain media in a sealed-off configuration, this thesis aims to formulate the scaling laws and characterise the main features of these devices. To help establish a design baseline and to allow the determination of practical results, the scaling laws are developed with an (arbitrary) limit on the physical size of the laser module of 100 x 10 x 10cm. Within this size, design algorithms demonstrate the limitation on scaling power to about 460W. Output beam characteristics are investigated for a range of multifold lasers to determine the effects the choice of design parameters has and the predicted TEM _{00} output expected. All incongruities are found to be primarily dependent on whether or not the beam traverses the complete Herriott Cell, but more directly on the radial gain and refractive index variations present in the gain medium. In terms of polarization, image rotation and astigmatism, the Cell has been analysed to determine the non-planar influence. Theoretical and experimental results tie in with the conclusions from the previous observations. The use of tolerance equations and a study of deviations in beam spot positions on the mirrors under misalignments illustrates; dependence on electrode dimensions; greatest sensitivity to Cell mirror tilts; and a shift in the ray envelope cross-section from circular to elliptical on all resonator adjustments. At all stages results are compared with existing multifold lasers and other lasers with similar output powers. As a whole the thesis demonstrates the potential of these lasers in the medium power range as sealed-off devices with excellent mode quality. Increased

  11. Microchannel plate fabrication using glass capillary arrays with Atomic Layer Deposition films for resistance and gain

    Science.gov (United States)

    Popecki, M. A.; Adams, B.; Craven, C. A.; Cremer, T.; Foley, M. R.; Lyashenko, A.; O'Mahony, A.; Minot, M. J.; Aviles, M.; Bond, J. L.; Stochaj, M. E.; Worstell, W.; Elam, J. W.; Mane, A. U.; Siegmund, O. H. W.; Ertley, C.; Kistler, L. M.; Granoff, M. S.

    2016-08-01

    Microchannel plates (MCPs) have been used for many years in space flight instrumentation as fast, lightweight electron multipliers. A new MCP fabrication method combines a glass substrate composed of hollow glass capillary arrays with thin film coatings to provide the resistive and secondary electron emissive properties. Using this technique, the gain, resistance, and glass properties may be chosen independently. Large-area MCPs are available at moderate cost. Secondary emission films of Al2O3 and MgO provide sustained high gain as charge is extracted from the MCP. Long lifetimes are possible, and a total extracted charge of 7 C/cm2 has been demonstrated. Background rates are low because the glass substrate has little radioactive potassium 40. Curved MCPs are easily fabricated with this technique to suit instrument symmetries, simplifying secondary electron steering and smoothing azimuthal efficiency.

  12. Stabilizing Gain Selection of Networked Variable Gain Controller to Maximize Robustness Using Particle Swarm Optimization

    CERN Document Server

    Pan, Indranil; Ghosh, Soumyajit; Gupta, Amitava; 10.1109/PACC.2011.5978958

    2012-01-01

    Networked Control Systems (NCSs) are often associated with problems like random data losses which might lead to system instability. This paper proposes a method based on the use of variable controller gains to achieve maximum parametric robustness of the plant controlled over a network. Stability using variable controller gains under data loss conditions is analyzed using a suitable Linear Matrix Inequality (LMI) formulation. Also, a Particle Swarm Optimization (PSO) based technique is used to maximize parametric robustness of the plant.

  13. Suppressed Auger Recombination in “Giant” Nanocrystals Boosts Optical Gain Performance

    OpenAIRE

    García-Santamaría, Florencio; Chen, Yongfen; Vela, Javier; Schaller, Richard D.; Hollingsworth, Jennifer A.; Klimov, Victor I.

    2009-01-01

    Many potential applications of semiconductor nanocrystals are hindered by nonradiative Auger recombination wherein the electron–hole (exciton) recombination energy is transferred to a third charge carrier. This process severely limits the lifetime and bandwidth of optical gain, leads to large nonradiative losses in light-emitting diodes and photovoltaic cells, and is believed to be responsible for intermittency (“blinking”) of emission from single nanocrystals. The development of nanostructur...

  14. The Preference of Keeping the Intermediary /y/(ی in Prepositional Construction and Its Attachment to the Silent» h«.

    Directory of Open Access Journals (Sweden)

    Mohammad Irani

    2010-06-01

    Full Text Available Abstract   One of the problems of Persian writing is the question of writing and including the noun or adjective "Prepositional" construction sign in words the written form of which end in a silent » h « which is in fact a short vowel equivalent to /e/ (kasra ـِـ .The difference between the two ways of writing the intermediary consonant /y/( ی at the end of the word with a last silent » h « , completely as « ی » or with the sign « ء» on the silent » h « is rooted in the controversy between the traditional and modern approaches of writing.   The present study is about to study into the following subjects: an analysis and criticism of both the above approaches, a survey of the history of the intermediary /y/( ی , recognizing its phonetic significance and its role in making and adding new syllables, and finally a conclusion about the more convenient way to write it. It is possible that the outcome of the present study will provide us with a unique form of writing of the case in different texts like books, articles, newspapers, journals and electronic texts.

  15. LC-MS Proteomics Analysis of the Insulin/IGF-1 Deficient Caenorhabditis elegans daf-2(e1370) Mutant Reveals Extensive Restructuring of Intermediary Metabolism

    Energy Technology Data Exchange (ETDEWEB)

    Depuydt, Geert G.; Xie, Fang; Petyuk, Vladislav A.; Smolders, Arne; Brewer, Heather M.; Camp, David G.; Smith, Richard D.; Braeckman, Bart P.

    2014-02-20

    The insulin/IGF-1 receptor is a major known determinant of dauer formation, stress resistance, longevity and metabolism in C. elegans. In the past, whole-genome transcript profiling was used extensively to study differential gene expression in response to reduced insulin/IGF-1 signaling, including expression levels of metabolism-associated genes. Taking advantage of the recent developments in quantitative liquid chromatography mass-spectrometry (LC-MS) based proteomics, we profiled the proteomic changes that occur in response to activation of the DAF-16 transcription factor in the germline-less glp-4(bn2); daf-2(e1370) receptor mutant. Strikingly, the daf-2 profile suggests extensive reorganization of intermediary metabolism, characterized by the up-regulation of many core intermediary metabolic pathways. These include, glycolysis/gluconeogenesis, glycogenesis, pentose phosphate cycle, citric acid cycle, glyoxylate shunt, fatty acid β-oxidation, one-carbon metabolism, propionate and tyrosine catabolism, and complex I, II, III and V of the electron transport chain. Interestingly, we found simultaneous activation of reciprocally regulated metabolic pathways, which is indicative for spatio-temporal coordination of energy metabolism and/or extensive post-translational regulation of these enzymes. This restructuring of daf-2 metabolism is reminiscent to that of hypometabolic dauers, allowing the efficient and economical utilization of internal nutrient reserves, possibly also shunting metabolites through alternative energy-generating pathways, in order to sustain longevity.

  16. LC–MS Proteomics Analysis of the Insulin/IGF-1-Deficient Caenorhabditis elegans daf-2(e1370) Mutant Reveals Extensive Restructuring of Intermediary Metabolism

    Energy Technology Data Exchange (ETDEWEB)

    Depuydt, Geert; Xie, Fang; Petyuk, Vladislav A.; Smolders, Arne; Brewer, Heather M.; Camp, David G.; Smith, Richard D.; Braeckman, Bart P.

    2014-04-04

    The insulin/IGF-1 receptor is a major known determinant of dauer formation, stress resistance, longevity, and metabolism in Caenorhabditis elegans. In the past, whole-genome transcript profiling was used extensively to study differential gene expression in response to reduced insulin/IGF-1 signaling, including the expression levels of metabolism-associated genes. Taking advantage of the recent developments in quantitative liquid chromatography mass spectrometry (LC–MS)-based proteomics, we profiled the proteomic changes that occur in response to activation of the DAF-16 transcription factor in the germline-less glp-4(bn2);daf-2(e1370) receptor mutant. Strikingly, the daf-2 profile suggests extensive reorganization of intermediary metabolism, characterized by the upregulation of many core intermediary metabolic pathways. These include glycolysis/gluconeogenesis, glycogenesis, pentose phosphate cycle, citric acid cycle, glyoxylate shunt, fatty acid β-oxidation, one-carbon metabolism, propionate and tyrosine catabolism, and complexes I, II, III, and V of the electron transport chain. Interestingly, we found simultaneous activation of reciprocally regulated metabolic pathways, which is indicative of spatiotemporal coordination of energy metabolism and/or extensive post-translational regulation of these enzymes. Finally, this restructuring of daf-2 metabolism is reminiscent to that of hypometabolic dauers, allowing the efficient and economical utilization of internal nutrient reserves and possibly also shunting metabolites through alternative energy-generating pathways to sustain longevity.

  17. Effect of fishmeal replacement by soy protein concentrate with taurine supplementation on hepatic intermediary metabolism and antioxidant status of totoaba juveniles (Totoaba macdonaldi).

    Science.gov (United States)

    Bañuelos-Vargas, Isaura; López, Lus M; Pérez-Jiménez, Amalia; Peres, Helena

    2014-04-01

    The effect of dietary incorporation of soy protein concentrate (SPC) and the concomitant supplementation with taurine on hepatic intermediary metabolism and antioxidant status of totoaba (Totoaba macdonaldi) juveniles was assessed. Four isoproteic and isolipidic diets were formulated containing either 30 or 60% of SPC (diets SP30 and SP60), supplemented or not with 1% of taurine (diets SP30T and SP60T). A fish meal (FM) based diet, without SPC and taurine supplementation, was used as a control. Triplicate groups of 32 totoaba juveniles (average body mass=7.5g) were fed these diets over 45days. Results revealed that dietary FM replacement by SPC depressed the overall intermediary metabolism. Activity of key enzymes of amino acid catabolism and gluconeogenesis was significantly reduced and a trend to reduce glycolysis and glucose-6-phosphate dehydrogenase activity was observed. The incorporation of the highest level of SPC also significantly increased hepatic lipid peroxidation and the activity of superoxide dismutase. Concomitant taurine supplementation restored the activity of amino acid catabolic and gluconeogenic enzymes and hexokinase to levels similar of those of the control diet. Taurine supplementation also led to a significant increase of glucose-6-phosphate dehydrogenase and catalase activity, as well as to a significant reduction of liver lipid peroxidation. These results suggest that taurine may play an important metabolic modulation action on totoaba fed SPC based diets, contributing to the enhancement of the overall metabolism and to the reduction of liver oxidative damage.

  18. Mastering the intermediaries.

    Science.gov (United States)

    Edelman, Benjamin

    2014-06-01

    Almost every retailer looks to Google to refer customers, and it's rare to find a manufacturer whose products aren't sold on Amazon. But these and other big platforms can capture a disproportionate share of the value a company creates: Buy an app on iTunes, and Apple takes 30%. The author presents four strategies to help businesses reduce their dependence on powerful platforms. Exploit the platform's need to be comprehensive. American Airlines' strong coverage of key routes made its presence on the travel website Kayak indispensable to Kayak's value proposition. As a result, AA negotiated a better deal. Identify and discredit discrimination. Public complaints that eBay was giving search prominence to suppliers who advertised on the site forced a reversal of the policy. Create an alternative platform. When MovieTickets was on the verge of dominating phone and online ticketing, Regal Entertainment and two other large theater chains formed Fandango. Deal more directly. People ordering takeout through online platforms like Foodler and GrubHub have often already chosen their restaurant. Restaurants that deal directly can exit the platform.

  19. Double-pass ytterbium-doped fiber amplifier with high gain coefficient and low noise figure

    Institute of Scientific and Technical Information of China (English)

    Anting Wang(王安廷); Meishu Xing(邢美术); Guanghui Chen(陈光辉); Wenkui Yang(杨文奎); Hai Ming(明海); Jianping Xie(谢建平); Yunxia Wu(吴云霞)

    2003-01-01

    We have proposed and demonstrated a double-pass ytterbium-doped fiber amplifier using an optical circulator and a fiber Bragg grating as reflector. When the signal has passed through the ytterbium-doped fiber once, it reflects off a 0.2-nm passive fiber Bragg grating filter. This reduces amplified spontaneous emission (ASE) noise from the first pass. The input signal light is amplified both forward and backward through ytterbium-doped fiber. With this double-pass configuration, 1053.15-nm unsaturated signal gain of 28 dB, gain coefficient of 1.1 dB/mW, and noise figure of less than 4 dB are achieved at 977-nm pump power of 68 mW. It is also found that this double-pass configure provides enhancing gain coefficient and improving noise figure by comparison with single-pass configuration.

  20. Quantum limited noise figure operation of high gain erbium doped fiber amplifiers

    DEFF Research Database (Denmark)

    Lumholt, Ole; Povlsen, Jørn Hedegaard; Schüsler, Kim;

    1993-01-01

    powers below -5 dBm, and an improvement of 2.0 dB with a simultaneous gain increase of 4.1 dB is measured relative to a gain-optimized fiber. The optimum isolator location is evaluated for different pump and signal wavelengths in both an Al/Er-doped and a Ge/Er-doped fiber, for pump and signal power......Performance improvements obtained by using an isolator as an amplified-spontaneous-emission-suppressing component within erbium-doped fibers are evaluated. Simultaneous high-gain and near-quantum-limited noise figures can be obtained by such a scheme. The noise figure improves for input signal...... variations and different pump configurations. In all cases the optimum isolator position lies within 10-37% of the total fiber length for small signal operation...