WorldWideScience

Sample records for interim results presentation

  1. AES Water Architecture Study Interim Results

    Science.gov (United States)

    Sarguisingh, Miriam J.

    2012-01-01

    The mission of the Advanced Exploration System (AES) Water Recovery Project (WRP) is to develop advanced water recovery systems in order to enable NASA human exploration missions beyond low earth orbit (LEO). The primary objective of the AES WRP is to develop water recovery technologies critical to near term missions beyond LEO. The secondary objective is to continue to advance mid-readiness level technologies to support future NASA missions. An effort is being undertaken to establish the architecture for the AES Water Recovery System (WRS) that meets both near and long term objectives. The resultant architecture will be used to guide future technical planning, establish a baseline development roadmap for technology infusion, and establish baseline assumptions for integrated ground and on-orbit environmental control and life support systems (ECLSS) definition. This study is being performed in three phases. Phase I of this study established the scope of the study through definition of the mission requirements and constraints, as well as indentifying all possible WRS configurations that meet the mission requirements. Phase II of this study focused on the near term space exploration objectives by establishing an ISS-derived reference schematic for long-duration (>180 day) in-space habitation. Phase III will focus on the long term space exploration objectives, trading the viable WRS configurations identified in Phase I to identify the ideal exploration WRS. The results of Phases I and II are discussed in this paper.

  2. Interim Results on Improvement of Melia volkensii

    International Nuclear Information System (INIS)

    Kariuki, J.G.; Kimondo, J.M; Muchri, D.K

    2007-01-01

    Melia volkensii is important in some dry lands of Kenya as a high quality timber, for fodder, shade and construction. It is both drought resistant and fast growing and is termite resistant. Demand for the species has led to dysgenic selection, resulting in the selection of superior trees, progressively leading to a pool of poor parent trees remaining in most populations. A genetic improvement strategy and implementation plan was initiated in the year 2005. The main objective was genetic improvement of melia volkensii through selection, breeding and propagation. Specific objectives was to develop new plantations that are superior to their predecessors in one or several key economic traits and to maximize value of logs produced by farmers. The basic material for selection of plus trees were the natural and on farm populations across most of the species' natural range. Selection was carried out in nine transects located in various areas from Isiolo to Voi, through assessment of candidate trees and subsequent comparison with nearest 5 check trees. Site characterization and passport data collection was also carried out. Various selection criteria were used including diameter at breast height (dbh), height, form (straightness and branching habit), resistance to diseases, pests and spiral grain tendency. For establishment of hedges , stressing of root through severing part of the root to produce scions was done, followed by scion selection and grafting. Initial results showed the existence of two main forms in M. volkensii i.e crop and tree ideotypes. Crop ideotypes are shorter, have shorter clear boles with deep large and spreading crowns, mainly found in Mwingi, Nuu, Tseikuru and some parts of Kitui. Tree ideotypes are taller with long clear boles, light branching and sparce crowns mainly found in Voi, Mbeere,Mutha and Embu. Intermediate forms also exist. Because the breeding objective was timber production, the tree ideotypes were favoured in selection. In all nine

  3. SWSA 6 interim corrective measures environmental monitoring: FY 1990 results

    Energy Technology Data Exchange (ETDEWEB)

    Ashwood, T.L.; Spalding, B.P.

    1991-07-01

    This report presents the results and conclusions from a multifaceted monitoring effort associated with the high-density polyethylene caps installed in Solid Waste Storage Area (SWSA) 6 at Oak Ridge National Laboratory (ORNL) as an interim corrective measure (ICM). The caps were installed between November 1988 and June 1989 to meet Resource Conservation and Recovery Act (RCRA) requirements for closure of those areas of SWSA 6 that had received RCRA-regulated wastes after November 1980. Three separate activities were undertaken to evaluate the performance of the caps: (1) wells were installed in trenches to be covered by the caps, and water levels in these intratrench wells were monitored periodically; (2) samples were taken of the leachate in the intratrench wells and were analyzed for a broad range of radiological and chemical contaminants; and (3) water levels in wells outside the trenches were monitored periodically. With the exception of the trench leachate sampling, each of these activities spanned the preconstruction, construction, and postconstruction periods. Findings of this study have important implications for the ongoing remedial investigation in SWSA 6 and for the design of other ICMs. 51 figs., 2 tabs.

  4. Honeywell Cascade Distiller System Performance Testing Interim Results

    Science.gov (United States)

    Callahan, Michael R.; Sargusingh, Miriam

    2014-01-01

    The ability to recover and purify water through physiochemical processes is crucial for realizing long-term human space missions, including both planetary habitation and space travel. Because of their robust nature, distillation systems have been actively pursued as one of the technologies for water recovery. The Cascade Distillation System (CDS) is a vacuum rotary distillation system with potential for greater reliability and lower energy costs than existing distillation systems. The CDS was previously under development through Honeywell and NASA. In 2009, an assessment was performed to collect data to support down-selection and development of a primary distillation technology for application in a lunar outpost water recovery system. Based on the results of this testing, an expert panel concluded that the CDS showed adequate development maturity, TRL-4, together with the best product water quality and competitive weight and power estimates to warrant further development. The Advanced Exploration Systems (AES) Water Recovery Project (WRP) worked to address weaknesses identified by The Panel; namely bearing design and heat pump power efficiency. Testing at the NASA-JSC Advanced Exploration System Water Laboratory (AES Water Lab) using a prototype Cascade Distillation Subsystem (CDS) wastewater processor (Honeywell International, Torrance, Calif.) with test support equipment and control system developed by Johnson Space Center was performed to evaluate performance of the system with the upgrades. The CDS will also have been challenged with ISS analog waste streams and a subset of those being considered for Exploration architectures. This paper details interim results of the AES WRP CDS performance testing.

  5. Interim results from UO2 fuel oxidation tests in air

    International Nuclear Information System (INIS)

    Campbell, T.K.; Gilbert, E.R.; Thornhill, C.K.; White, G.D.; Piepel, G.F.; Griffin, C.W.j.

    1987-08-01

    An experimental program is being conducted at Pacific Northwest Laboratory (PNL) to extend the characterization of spent fuel oxidation in air. To characterize oxidation behavior of irradiated UO 2 , fuel oxidation tests were performed on declad light-water reactor spent fuel and nonirradited UO 2 pellets in the temperature range of 135 to 250 0 C. These tests were designed to determine the important independent variables that might affect spent fuel oxidation behavior. The data from this program, when combined with the test results from other programs, will be used to develop recommended spent fuel dry-storage temperature limits in air. This report describes interim test results. The initial PNL investigations of nonirradiated and spent fuels identified the important testing variables as temperature, fuel burnup, radiolysis of the air, fuel microstructure, and moisture in the air. Based on these initial results, a more extensive statistically designed test matrix was developed to study the effects of temperature, burnup, and moisture on the oxidation behavior of spent fuel. Oxidation tests were initiated using both boiling-water reactor and pressurized-water reactor fuels from several different reactors with burnups from 8 to 34 GWd/MTU. A 10 5 R/h gamma field was applied to the test ovens to simulate dry storage cask conditions. Nonirradiated fuel was included as a control. This report describes experimental results from the initial tests on both the spent and nonirradiated fuels and results to date on the tests in a 10 5 R/h gamma field. 33 refs., 51 figs., 6 tabs

  6. Interim Restorative Approach for the Management of Congenitally Missing Permanent Mandibular Incisors: Presentation of Three Cases

    Directory of Open Access Journals (Sweden)

    Prashanth Prakash

    2011-01-01

    Full Text Available Congenital missing of mandibular permanent incisors with retained primary incisors may jeopardize the esthetic appearance and psychological development of children, especially during the years of transition into adolescence. The retained primary teeth are necessary for the maintenance and normal development of alveolar bone, which in turn is essential for future definitive rehabilitation. In such situations, an interim restoration may be provided before any definitive treatment is given to comfort the young patient during this transition period. Interim restorations may include resin-modified additions to the existing teeth as well as more sophisticated restorations such as resin-retained bridge and removable partial dentures. However, this restoration differs for different clinical situations based on various factors such as age and patient compliance, and also consideration has to be given for the growth changes of the child. The aim of this present paper is to discuss the esthetic management of three cases with bilateral agenesis of permanent mandibular incisors and retained primary incisors with composite interim restoration.

  7. Fast Flux Test Facility interim examination and maintenance cell: Past, present, and future

    International Nuclear Information System (INIS)

    Vincent, J.R.

    1990-09-01

    The Fast Flux Test Facility Interim Examination and Maintenance Cell was designed to perform interim examination and/or disassembly of experimental core components for final analysis elsewhere, as well as maintenance of sodium-wetted or neutron-activated internal reactor parts and plant support hardware. The Interim Examination and Maintenance Cell equipment developed and used for the first ten years of operation has been primarily devoted to the disassembly and examination of core component test assemblies. While no major reactor equipment has required remote repair or maintenance, the Interim Examina Examination and Maintenance Cell has served as the remote repair facility for its own in-cell equipment, and several innovative remote repairs have been accomplished. The Interim Examination and Maintenance Cell's demonstrated versatility has shown its capability to support a challenging future. 12 refs., 9 figs

  8. Interim restorations.

    Science.gov (United States)

    Gratton, David G; Aquilino, Steven A

    2004-04-01

    Interim restorations are a critical component of fixed prosthodontic treatment, biologically and biomechanically. Interim restoration serves an important diagnostic role as a functional and esthetic try-in and as a blueprint for the design of the definitive prosthesis. When selecting materials for any interim restoration, clinicians must consider physical properties, handling properties, patient acceptance, and material cost. Although no single material meets all the requirements and material classification alone of a given product is not a predictor of clinical performance, bis-acryl materials are typically best suited to single-unit restorations, and poly(methylmethacrylate) interim materials are generally ideal for multi-unit, complex, long-term, interim fixed prostheses. As with most dental procedures, the technique used for fabrication has a greater effect on the final result than the specific material chosen.

  9. Presentation of the results 97

    International Nuclear Information System (INIS)

    1998-01-01

    Gaz de France (GDF) presents in a press kit the main results achieved in 1997. The European community has formulated a project of definition of rules concerning the natural gas market. Minima values for annual consumptions have been defined and the consumption and use of natural gas in EC countries is described. The financial results of GDF in 1997 are compared with previous years. Net sales grew by nearly 1 billion french francs to reach 55 billion. Overall sales were down by 4% but the share of natural gas in french energy consumption increased and sales to industrial users went up in particular due to new cogeneration plants installed in 1996. A comparison of gas prices in Europe is given for the years 1985 to 1998. The efforts of GDF to offer increased quality of services concerning in particular safety aspects as checking programs and installation of new safeguard appliances are described. The efforts of GDF to increase the energy market share of natural gas resulted in the development of new products like cogeneration, air conditioning and fuels for automotive needs. (C.B.)

  10. SWSA 6 interim corrective measures environmental monitoring: FY 1990 results. Environmental Restoration Program

    Energy Technology Data Exchange (ETDEWEB)

    Ashwood, T.L.; Spalding, B.P.

    1991-07-01

    This report presents the results and conclusions from a multifaceted monitoring effort associated with the high-density polyethylene caps installed in Solid Waste Storage Area (SWSA) 6 at Oak Ridge National Laboratory (ORNL) as an interim corrective measure (ICM). The caps were installed between November 1988 and June 1989 to meet Resource Conservation and Recovery Act (RCRA) requirements for closure of those areas of SWSA 6 that had received RCRA-regulated wastes after November 1980. Three separate activities were undertaken to evaluate the performance of the caps: (1) wells were installed in trenches to be covered by the caps, and water levels in these intratrench wells were monitored periodically; (2) samples were taken of the leachate in the intratrench wells and were analyzed for a broad range of radiological and chemical contaminants; and (3) water levels in wells outside the trenches were monitored periodically. With the exception of the trench leachate sampling, each of these activities spanned the preconstruction, construction, and postconstruction periods. Findings of this study have important implications for the ongoing remedial investigation in SWSA 6 and for the design of other ICMs. 51 figs., 2 tabs.

  11. Presentation of RTE results 2003

    International Nuclear Information System (INIS)

    2004-01-01

    For RTE, the financial year 2003 was marked by a number of achievements: our financial performances registered a clear improvement, above objectives, with turnover growing strongly; net income reached levels almost three times higher than those recorded in 2002; the economic rate of return rose to 7.1%; and debt was reduced by 470 Meuros. These results are explained by the substantial improvement in productivity, which has risen by 5% per year on average over the last three years

  12. Presentation of RTE results 2003

    International Nuclear Information System (INIS)

    2003-01-01

    In 2003, RTE recorded a clear improvement in its financial results, and continued its debt reduction programme. The financial year 2003 was marked by a clear improvement in RTE's financial performance: results exceeded objectives, with turnover growing strongly, net income reached levels almost three times higher than those recorded in 2002, the economic rate of return rose to 7.1%, and debt was reduced by 470 Meuros. These results are explained by the substantial improvement in productivity, which has risen by 5% per year on average over the last three years. Net income has almost tripled due to RTE's improved productivity completed by a significant rise in its turnover and stabilizing operating costs RTE's finances therefore remain healthy, enabling the company to continue its debt reduction programme. Satisfactory economic and financial rates of return. Deadlines facing RTE in 2004: in application of the second European Directive, adopted on 26 June 2003, RTE faces two major deadlines in 2004: - the implementation of the 2. phase in the process of opening up the French electricity market, - its legal independence. On 1 July 2004, the market will be opened up to competition for all professional customers. At that date RTE, like all other electricity transmission system operators (TSOs) in the European Union, should be a legally independent body. The new central role of TSOs in Europe: how are electricity transmission system operators in other EU countries organised?

  13. Immediate loading of trabecular metal-enhanced titanium dental implants: interim results from an international proof-of-principle study.

    Science.gov (United States)

    Schlee, Marcus; van der Schoor, W Peter; van der Schoor, Alexandra R M

    2015-01-01

    A 3-year proof-of-principle study was initiated to evaluate the clinical efficacy of immediately loading titanium dental implants with surfaces enhanced with porous tantalum trabecular metal (PTTM). First-year interim results are presented. Healthy, partially edentulous patients (n = 30) were enrolled and treated per protocol (minimum insertion torque: ≥35 Ncm) with 37 implants placed in one or two premolar or molar locations in either jaw (study group). Implants were immediately provisionalized out of occlusion with single acrylic crowns. After 7 to 14 days of soft tissue healing, implants were definitively restored in occlusion with ceramometal crowns. Because most study group implants (54.1%, n = 20) had less than 1 year of clinical follow-up, this interim analysis was limited to the first 22 consecutively placed implants in 17 subjects (10 women and 7 men) who completed 1 year of clinical follow-up to date (focus group). To date, one implant failed to integrate in the study group (survival = 97.3%, n = 36/37). Focus group implants achieved 100% (n = 22/22) survival with 0.43 ± 0.41 mm of mean marginal bone loss. There were no serious complications. Early clinical findings indicated that immediate loading of PTTM implants was safe and effective under the controlled study conditions. © 2013 The Authors. Clinical Implant Dentistry and Related Research published by Wiley Periodicals, Inc.

  14. Interim report on Mitsubishi's results using rainbow for stage 1 verification

    International Nuclear Information System (INIS)

    Ohkubo, Y.; Kinjo, H.; Itoh, K.

    1990-01-01

    Analytical work on the benchmark problems is underway at Mitsubishi by using RAINBOW code. This interim report contains the results of examples 1, 2, 4 and 5. In the following, the brief outline of RAINBOW code is described, and then the analyzed results of the examples are reported. RAINBOW code is a three-dimensional core deformation analysis code developed by Mitsubishi Atomic Power Industries, Inc. In the RAINBOW code, core elements are approximated in straight beams and the beam theory is applied in the analysis of their deflections due to mechanical interactions among core elements. It can handle various sectors of the whole core, assuming a boundary condition of rotational or reflective symmetry. (author). 6 tabs, figs

  15. Deep Vadose Zone Treatability Test for the Hanford Central Plateau: Interim Post-Desiccation Monitoring Results

    Energy Technology Data Exchange (ETDEWEB)

    Truex, Michael J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Oostrom, Martinus [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Strickland, Christopher E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Johnson, Timothy C. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Johnson, Christian D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Clayton, Ray E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Chronister, Glen B. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2013-09-01

    A field test of desiccation is being conducted as an element of the deep vadose zone treatability test program. Desiccation technology relies on removal of water from a portion of the subsurface such that the resultant low moisture conditions inhibit downward movement of water and dissolved contaminants. Previously, a field test report (Truex et al. 2012a) was prepared describing the active desiccation portion of the test and initial post-desiccation monitoring data. Additional monitoring data have been collected at the field test site during the post-desiccation period and is reported herein along with interpretation with respect to desiccation performance. This is an interim report including about 2 years of post-desiccation monitoring data.

  16. Sample results from the interim salt disposition program macrobatch 9 tank 21H qualification samples

    Energy Technology Data Exchange (ETDEWEB)

    Peters, T. B. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2015-11-01

    Savannah River National Laboratory (SRNL) analyzed samples from Tank 21H in support of qualification of Macrobatch (Salt Batch) 9 for the Interim Salt Disposition Program (ISDP). This document reports characterization data on the samples of Tank 21H.

  17. Results from the Interim Salt Disposition Program Macrobatch 11 Tank 21H Acceptance Samples

    Energy Technology Data Exchange (ETDEWEB)

    Peters, T. B. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Bannochie, C. J. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2017-11-13

    Savannah River National Laboratory (SRNL) analyzed samples from Tank 21H in support of verification of Macrobatch (Salt Batch) 11 for the Interim Salt Disposition Program (ISDP) for processing. This document reports characterization data on the samples of Tank 21H and fulfills the requirements of Deliverable 3 of the Technical Task Request (TTR).

  18. Continuation of the summarizing interim report on previous results of the Gorleben site survey as of May 1983

    International Nuclear Information System (INIS)

    1990-04-01

    In addition to results from the 1983 interim report, this report contains, in order to supplement the surface explorations, seismic reflection measurements, hydrogeologic and seismologic investigations, sorption experiments, and studies of glacial development in the site region and of long-term safety of final waste repositories in salt domes. The site's high grade of suitability for becoming a final radioactive waste repository, the legal basis as well as quality assurance are evaluated. (orig.) [de

  19. Emulytics for Cyber-Enabled Physical Attack Scenarios: Interim LDRD Report of Year One Results.

    Energy Technology Data Exchange (ETDEWEB)

    Clem, John [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Urias, Vincent [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Atkins, William Dee [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Symonds, Christopher J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-12-08

    Sandia National Laboratories has funded the research and development of a new capability to interactively explore the effects of cyber exploits on the performance of physical protection systems. This informal, interim report of progress summarizes the project’s basis and year one (of two) accomplishments. It includes descriptions of confirmed cyber exploits against a representative testbed protection system and details the development of an emulytics capability to support live, virtual, and constructive experiments. This work will support stakeholders to better engineer, operate, and maintain reliable protection systems.

  20. Safety and Effectiveness of Natalizumab: First Report of Interim Results of Post-Marketing Surveillance in Japan.

    Science.gov (United States)

    Saida, Takahiko; Yokoyama, Kazumasa; Sato, Ryusuke; Makioka, Haruki; Iizuka, Yukihiko; Hase, Masakazu; Ling, Yan; Torii, Shinichi

    2017-12-01

    Natalizumab, a humanized anti-α4 integrin monoclonal antibody, received marketing approval in Japan in 2014 for the treatment of multiple sclerosis (MS). Because the previous large-scale clinical trials of natalizumab were mainly conducted in Europe and North American countries, and data in patients with MS from Japan were limited, we conducted an all-case post-marketing surveillance of natalizumab-treated MS patients from Japan to investigate the safety and effectiveness of natalizumab in a real-world clinical setting in Japan. Here, we report the results of an interim analysis. During the observation period of 2 years, all patients who were treated with natalizumab subsequent to its approval in Japan were followed. The effectiveness of natalizumab was assessed by examining the changes in expanded disability status scale (EDSS) score and annualized relapse rate (ARR) from baseline. Safety was assessed by analyzing the incidence of adverse drug reactions (ADRs). The safety analysis included 106 patients (mean age 39.3 years; women 62.3%) whose data were collected until the data lock point (February 7, 2016). The effectiveness analysis included 75 patients. The majority of patients had relapsing-remitting MS (93/106 patients; 87.7%). The mean length of treatment exposure in the present study was 6.6 months. During the 2-year observation period, no significant change in the EDSS was observed, while the ARR decreased significantly from baseline (72.9% reduction, p = 0.001). ADRs and serious ADRs were observed in 11.3% and 3.8% of patients, respectively; however, no new safety concerns were detected. No patient had progressive multifocal leukoencephalopathy (PML) during the present study period. The safety and effectiveness of natalizumab were confirmed in Japanese patients with MS in clinical practice. Nevertheless, potential risks including PML require continuous, careful observation. Biogen Japan Ltd (Tokyo, Japan).

  1. Results from the interim salt disposition program macrobatch 10 tank 21H qualification samples

    Energy Technology Data Exchange (ETDEWEB)

    Peters, T. B. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Bannochie, C. J. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2017-02-23

    Savannah River National Laboratory (SRNL) analyzed samples from Tank 21H in support of qualification of Macrobatch (Salt Batch) 10 for the Interim Salt Disposition Program (ISDP). This document reports characterization data on the samples of Tank 21H and fulfills the requirements of Deliverable 3 of the Technical Task Request (TTR). Further work will report the results of the Extraction-Scrub-Strip (ESS) testing (Task 5 of the TTR) using the Tank 21H material. Task 4 of the TTR (MST Strike) will not be completed for Salt Batch 10.

  2. ISO Results Presented at International Astronomical Union

    Science.gov (United States)

    1997-08-01

    Some of the work being presented is collected in the attached ESA Information Note N 25-97, ISO illuminates our cosmic ancestry. A set of six colour images illustrating various aspects have also been released and are available at http://www.estec.esa.nl/spdwww/iso1808.htm or in hard copy from ESA Public Relations Paris (fax:+33.1.5369.7690). These pictures cover: 1. Distant but powerful infrared galaxies 2. A scan across the milky way 3. Helix nebula: the shroud of a dead star 4. Supernova remnant Cassiopeia A 5. Trifid nebula: a dusty birthplace of stars 6. Precursors of stars and planets The International Astronomical Union provides a forum where astronomers from all over the world can develop astronomy in all its aspects through international co-operation. General Assemblies are held every three years. It is expected that over 1600 astronomers will attend this year's meeting, which is being held in Kyoto, Japan from 18-30 August. Further information on the meeting can be found at: www.tenmon.or.jp/iau97/ . ISO illuminates our cosmic ancestry The European Space Agency's Infrared Space Observatory, ISO, is unmatched in its ability to explore and analyse many of the universal processes that made our existence possible. We are children of the stars. Every atom in our bodies was created in cosmic space and delivered to the Sun's vicinity in time for the Earth's formation, during a ceaseless cycle of birth, death and rebirth among the stars. The most creative places in the sky are cool and dusty, and opaque even to the Hubble Space Telescope. Infrared rays penetrating the dust reveal to ISO hidden objects, and the atoms and molecules of cosmic chemistry. "ISO is reading Nature's recipe book," says Roger Bonnet, ESA's director of science. "As the world's only telescope capable of observing the Universe over a wide range of infrared wavelengths, ISO plays an indispensable part in astronomical discoveries that help to explain how we came to exist." This Information Note

  3. Independent Technical Review of the C-400 Interim Remedial Project Phase I Results, Paducah, Kentucky

    International Nuclear Information System (INIS)

    Looney, B.; Rossabi, J.; Stewart, L.; Richards, W.

    2010-01-01

    The groundwater and soil in the vicinity of the C-400 Building at the Paducah Gaseous Diffusion Plant (PGDP), is contaminated with substantial quantities of industrial solvents, primarily trichoroethene (TCE). This solvent 'source' is recognized as a significant challenge and an important remediation target in the overall environmental cleanup strategy for PGDP. Thus, the cleanup of the C-400 TCE Source is a principal focus for the Department of Energy (DOE) and its contractors, and for PGDP regulators and stakeholders. Using a formal investigation, feasibility study and decision process, Electrical Resistance Heating (ERH) was selected for the treatment of the soil and groundwater in the vicinity of C-400. ERH was selected as an interim action to remove 'a significant portion of the contaminant mass of TCE at the C-400 Cleaning Building area through treatment' with the longer term goal of reducing 'the period the TCE concentration in groundwater remains above its Maximum Contaminant Level (MCL).' ERH is a thermal treatment that enhances the removal of TCE and related solvents from soil and groundwater. The heterogeneous conditions at PGDP, particularly the high permeability regional gravel aquifer (RGA), are challenging to ERH. Thus, a phased approach is being followed to implement this relatively expensive and complex remediation technology. Conceptually, the phased approach encourages safety and efficiency by providing a 'lessons learned' process and allowing appropriate adjustments to be identified and implemented prior to follow-on phase(s) of treatment. More specifically, early deployment targeted portions of the challenging RGA treatment zone with relatively little contamination reducing the risk of adverse collateral impacts from underperformance in terms of heating and capture. Because of the importance and scope of the C-400 TCE source remediation activities, DOE chartered an Independent Technical Review (ITR) in 2007 to assess the C-400 ERH plans prior

  4. INDEPENDENT TECHNICAL REVIEW OF THE C-400 INTERIM REMEDIAL PROJECT PHASE I RESULTS, PADUCAH, KENTUCKY

    Energy Technology Data Exchange (ETDEWEB)

    Looney, B.; Rossabi, J.; Stewart,L.; Richards, W.

    2010-10-29

    The groundwater and soil in the vicinity of the C-400 Building at the Paducah Gaseous Diffusion Plant (PGDP), is contaminated with substantial quantities of industrial solvents, primarily trichoroethene (TCE). This solvent 'source' is recognized as a significant challenge and an important remediation target in the overall environmental cleanup strategy for PGDP. Thus, the cleanup of the C-400 TCE Source is a principal focus for the Department of Energy (DOE) and its contractors, and for PGDP regulators and stakeholders. Using a formal investigation, feasibility study and decision process, Electrical Resistance Heating (ERH) was selected for the treatment of the soil and groundwater in the vicinity of C-400. ERH was selected as an interim action to remove 'a significant portion of the contaminant mass of TCE at the C-400 Cleaning Building area through treatment' with the longer term goal of reducing 'the period the TCE concentration in groundwater remains above its Maximum Contaminant Level (MCL).' ERH is a thermal treatment that enhances the removal of TCE and related solvents from soil and groundwater. The heterogeneous conditions at PGDP, particularly the high permeability regional gravel aquifer (RGA), are challenging to ERH. Thus, a phased approach is being followed to implement this relatively expensive and complex remediation technology. Conceptually, the phased approach encourages safety and efficiency by providing a 'lessons learned' process and allowing appropriate adjustments to be identified and implemented prior to follow-on phase(s) of treatment. More specifically, early deployment targeted portions of the challenging RGA treatment zone with relatively little contamination reducing the risk of adverse collateral impacts from underperformance in terms of heating and capture. Because of the importance and scope of the C-400 TCE source remediation activities, DOE chartered an Independent Technical Review (ITR) in

  5. Randomized Clinical Trial Comparing Proton Beam Radiation Therapy with Transarterial Chemoembolization for Hepatocellular Carcinoma: Results of an Interim Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Bush, David A., E-mail: dbush@llu.edu [Department of Radiation Medicine, Loma Linda University Medical Center, Loma Linda, California (United States); Smith, Jason C. [Department of Diagnostic Radiology, Loma Linda University Medical Center, Loma Linda, California (United States); Slater, Jerry D. [Department of Radiation Medicine, Loma Linda University Medical Center, Loma Linda, California (United States); Volk, Michael L. [Transplantation Institute and Liver Center, Loma Linda University Medical Center, Loma Linda, California (United States); Reeves, Mark E. [VA Loma Linda Health Care System, Loma Linda, California (United States); Cheng, Jason [Transplantation Institute and Liver Center, Loma Linda University Medical Center, Loma Linda, California (United States); Grove, Roger [Department of Radiation Medicine, Loma Linda University Medical Center, Loma Linda, California (United States); Vera, Michael E. de [Transplantation Institute and Liver Center, Loma Linda University Medical Center, Loma Linda, California (United States)

    2016-05-01

    Purpose: To describe results of a planned interim analysis of a prospective, randomized clinical trial developed to compare treatment outcomes among patients with newly diagnosed hepatocellular carcinoma (HCC). Methods and Materials: Eligible subjects had either clinical or pathologic diagnosis of HCC and met either Milan or San Francisco transplant criteria. Patients were randomly assigned to transarterial chemoembolization (TACE) or to proton beam radiation therapy. Patients randomized to TACE received at least 1 TACE with additional TACE for persistent disease. Proton beam radiation therapy was delivered to all areas of gross disease to a total dose of 70.2 Gy in 15 daily fractions over 3 weeks. The primary endpoint was progression-free survival, with secondary endpoints of overall survival, local tumor control, and treatment-related toxicities as represented by posttreatment days of hospitalization. Results: At the time of this analysis 69 subjects were available for analysis. Of these, 36 were randomized to TACE and 33 to proton. Total days of hospitalization within 30 days of TACE/proton was 166 and 24 days, respectively (P<.001). Ten TACE and 12 proton patients underwent liver transplantation after treatment. Viable tumor identified in the explanted livers after TACE/proton averaged 2.4 and 0.9 cm, respectively. Pathologic complete response after TACE/proton was 10%/25% (P=.38). The 2-year overall survival for all patients was 59%, with no difference between treatment groups. Median survival time was 30 months (95% confidence interval 20.7-39.3 months). There was a trend toward improved 2-year local tumor control (88% vs 45%, P=.06) and progression-free survival (48% vs 31%, P=.06) favoring the proton beam treatment group. Conclusions: This interim analysis indicates similar overall survival rates for proton beam radiation therapy and TACE. There is a trend toward improved local tumor control and progression-free survival with proton beam. There are

  6. Extraction, -scrub, -strip test results from the interim salt disposition program macrobatch 10 tank 21H qualification samples

    Energy Technology Data Exchange (ETDEWEB)

    Peters, T. B. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2017-06-26

    Savannah River National Laboratory (SRNL) analyzed samples from Tank 21H in support of qualification of Macrobatch (Salt Batch) 10 for the Interim Salt Disposition Program (ISDP). The Salt Batch 10 characterization results were previously reported.ii,iii An Extraction, -Scrub, -Strip (ESS) test was performed to determine cesium distribution ratios (D(Cs)) and cesium concentration in the strip effluent (SE) and decontaminated salt solution (DSS) streams; this data will be used by Tank Farm Engineering to project a cesium decontamination factor (DF). This test used actual Tank 21H material, and a sample of the NGS Blend solvent currently being used at the Modular Caustic-Side Solvent Extraction Unit (MCU). The ESS test showed acceptable performance with an extraction D(Cs) value of 110. This value is consistent with results from previous salt batch ESS tests using similar solvent formulations. This is better than the predicted value of 39.8 from a recently created D(Cs) model.

  7. FES Training in Aging: interim results show statistically significant improvements in mobility and muscle fiber size

    Directory of Open Access Journals (Sweden)

    Helmut Kern

    2012-03-01

    Full Text Available Aging is a multifactorial process that is characterized by decline in muscle mass and performance. Several factors, including reduced exercise, poor nutrition and modified hormonal metabolism, are responsible for changes in the rates of protein synthesis and degradation that drive skeletal muscle mass reduction with a consequent decline of force generation and mobility functional performances. Seniors with normal life style were enrolled: two groups in Vienna (n=32 and two groups in Bratislava: (n=19. All subjects were healthy and declared not to have any specific physical/disease problems. The two Vienna groups of seniors exercised for 10 weeks with two different types of training (leg press at the hospital or home-based functional electrical stimulation, h-b FES. Demografic data (age, height and weight were recorded before and after the training period and before and after the training period the patients were submitted to mobility functional analyses and muscle biopsies. The mobility functional analyses were: 1. gait speed (10m test fastest speed, in m/s; 2. time which the subject needed to rise from a chair for five times (5x Chair-Rise, in s; 3. Timed –Up-Go- Test, in s; 4. Stair-Test, in s; 5. isometric measurement of quadriceps force (Torque/kg, in Nm/kg; and 6. Dynamic Balance in mm. Preliminary analyses of muscle biopsies from quadriceps in some of the Vienna and Bratislava patients present morphometric results consistent with their functional behaviors. The statistically significant improvements in functional testings here reported demonstrates the effectiveness of h-b FES, and strongly support h-b FES, as a safe home-based method to improve contractility and performances of ageing muscles.

  8. Spinal cord stimulation or prostacyclin in unrevascularizable arteriopathy of lower limbs (SPINAL study: interim analysis results

    Directory of Open Access Journals (Sweden)

    Pedrini L

    2014-04-01

    nonresponders in the iloprost arm underwent SCS implantation. Three severe adverse events (one fatal were recorded in the iloprost arm and four in SCS treatments. One-year limb salvage rates in SCS, iloprost treatment, and iloprost plus SCS implantation (I-SCS were 66.8%, 57.1%, and 100%, respectively (P=0.09, and survival rates were 73.2%, 93.9%, and 88.9%, respectively (P=0.45, confirming results of other studies that showed a trend toward better amputation-free salvage in the SCS group. The small number of recruited patients prevented statistical significance being reached. Pain reduction was obtained in 87% of SCS patients and 35% of those in the iloprost arm (P=0.001. Among the examined parameters, only the angiographic resistance index was an independent predictive value of good results after SCS implantation.Discussion and conclusion: The SPINAL study is the first RCT comparing SCS and iloprost. Although incomplete, it evaluated a sample greater than those studied in three out of five available RCTs on SCS. However, the small sample size reduced the statistical power of the study, with possible type II errors. SCS was associated with a quick and more effective answer to pain, with better tolerability and better early results, than iloprost, but without significant 1-year limb salvage-rate improvement. Iloprost improved the 1-year survival in spite of adverse events, and, following these results, perhaps should be administered before other treatments. The results of this trial suggest that prostanoids and SCS are not alternative treatments: as prostanoids present many contraindications and side effects, SCS can be considered the complementary and consecutive treatment for patients who are no longer treatable with open or endovascular revascularizations, and an alternative treatment only in patients with contraindication to prostanoids. The association of iloprost and SCS seems to produce a synergic activity even in patients who had ineffective prostanoid treatment. These

  9. Interim report on the result of the sodium boiling noise detection benchmark test

    International Nuclear Information System (INIS)

    Shinohara, Y.; Watanabe, K.

    1989-01-01

    The present paper deals with investigations of acoustic signals from a boiling experiment performed on the KNS I loop at KfK Karlsruhe. Signals have been analysed in frequency as well as in time domain. Signal characteristics successfully used to detect the boiling process have been found in time domain. (author). 6 figs, 1 tab

  10. Interim results: fines recycle testing using the 4-inch diameter primary graphite burner

    International Nuclear Information System (INIS)

    Palmer, W.B.

    1975-05-01

    The results of twenty-two HTGR primary burner runs in which graphite fines were recycled pneumatically to the 4-inch diameter pilot-plant primary fluidized-bed burner are described. The result of the tests showed that zero fines accumulation can easily be achieved while operating at plant equivalent burn rates. (U.S.)

  11. Interim Report on Heuristics about Inspection Parameters: Updates to Heuristics Resulting from Refinement on Projects

    Science.gov (United States)

    Shull, Forrest; Seaman, Carolyn; Feldman, Raimund; Haingaertner, Ralf; Regardie, Myrna

    2008-01-01

    In 2008, we have continued analyzing the inspection data in an effort to better understand the applicability and effect of the inspection heuristics on inspection outcomes. Our research goals during this period are: 1. Investigate the effect of anomalies in the dataset (e.g. the very large meeting length values for some inspections) on our results 2. Investigate the effect of the heuristics on other inspection outcome variables (e.g. effort) 3. Investigate whether the recommended ranges can be modified to give inspection planners more flexibility without sacrificing effectiveness 4. Investigate possible refinements or modifications to the heuristics for specific subdomains (partitioned, e.g., by size, domain, or Center) This memo reports our results to date towards addressing these goals. In the next section, the first goal is addressed by describing the types of anomalies we have found in our dataset, how we have addressed them, and the effect of these changes on our previously reported results. In the following section, on "methodology", we describe the analyses we have conducted to address the other three goals and the results of these analyses are described in the "results" section. Finally, we conclude with future plans for continuing our investigation.

  12. An interim assessment of the results of day-treatment in nursing homes

    NARCIS (Netherlands)

    Nies, H. L.G.R.

    1986-01-01

    Day-treatment has developed very rapidly in Dutch nursing homes. This development was due to several unproved positive expectations concerning the therapeutical results, the effects for relatives and caregivers at home and the substitutional effects of day-treatment. In this article these

  13. Automotive Mechanics Occupational Performance Survey. Interim Report.

    Science.gov (United States)

    Borcher, Sidney D.; Leiter, Paul B.

    The purpose of this federally-funded interim report is to present the results of a task inventory analysis survey of automotive mechanics completed by project staff within the Instructional Systems Design Program at the Center for Vocational and Technical Education. Intended for use in curriculum development for vocational education programs in…

  14. Secondary use of structured patient data: interim results of a systematic review.

    Science.gov (United States)

    Vuokko, Riikka; Mäkelä-Bengs, Päivi; Hyppönen, Hannele; Doupi, Persephone

    2015-01-01

    In addition to patient care, EHR data are increasingly in demand for secondary purposes, e.g. administration, research and enterprise resource planning. We conducted a systematic literature review and subsequent analysis of 85 articles focusing on the secondary use of structured patient records. We grounded the analysis on how patient records have been structured, how these structures have been evaluated and what are the main results achieved from the secondary use viewpoint. We conclude that secondary use requires complete and interoperable patient records, which in turn depend on better alignment of primary and secondary users' needs and benefits.

  15. 3D model as a dynamic compilation of knowledge: interim results on the city of Alet

    Directory of Open Access Journals (Sweden)

    Yann Bernard

    2017-05-01

    Full Text Available The late Iron Age capital of the Coriosolites, City of Alet, scattered today in a neighbourhood of Saint-Malo( France, has become since 2015 the subject of experimentations in digital archaeology. These have led us to define as objective a relevant three-dimensional (3Dreconstruction integrating different buildings, but also a precise topography, aspart of the coastal geomorphology, environmental vegetation and naval activities. First pillar of this reconstruction, 3D laser and magnetic surveys were conducted in order to get some digitised work supports, but also to raise some scientific issues. As part of the main Roman cities of Brittany, the historical study of the City began at least at the end of the 19thcentury and archaeological excavations began in the 1970s. So knowledge present in a wide spectrum of archaeological and historical references was then compiled. 3D reconstruction of the City, editable to adapt to new contributions and scientific discoveries, allows a dynamic synthesis of archaeological knowledge accumulated along the years. Because it was done within an archaeology laboratory, it was directly monitored and controlled iteratively by researchers in the field (site, area and period. This work currently allows archaeologists to face limits and constraints regarding this scientific process and better understand the organizational aspects of the City.

  16. Cancer early detection program based on awareness and clinical breast examination: Interim results from an urban community in Mumbai, India.

    Science.gov (United States)

    Gadgil, Anita; Sauvaget, Catherine; Roy, Nobhojit; Muwonge, Richard; Kantharia, Surita; Chakrabarty, Anuradha; Bantwal, Kanchan; Haldar, Indrani; Sankaranarayanan, Rengaswamy

    2017-02-01

    Indian women with breast cancer are usually diagnosed in advanced stages leading to poor survival. Improving breast awareness and increasing access to early diagnosis and adequate treatment has been advocated for breast cancer control. We implemented a program to increase awareness on breast cancer and access to its early detection in an occupational health care scheme in Mumbai, India. Breast awareness brochures were mailed annually between June 2013 and June 2016 to a cohort of 22,500 eligible women aged 30-69 years old receiving universal health care from an occupational health care scheme comprising of primary health centres and a referral secondary care hospital in Mumbai. Women with suspected breast cancers were provided with diagnostic investigations and treatment. Socio-demographic information and tumour characteristics were compared between the breast awareness pre-intervention period (Jan 2005-May 2013) and the breast awareness intervention period after four rounds of mailers (June 2013-June 2016). The proportion of women with early tumours and axillary lymph node negative cancers increased from 74% to 81% and 46% to 53% respectively, between the two periods. While the proportion of patients receiving breast conserving surgery increased from 39% to 51%, the proportion receiving chemotherapy decreased from 84% to 56%. Interim results following efforts to improve breast awareness and access to care in a cohort of women in an occupational health care scheme indicate early detection and more conservative treatment of breast cancers. Creating awareness and improving access to care may result in cancer down-staging. Copyright © 2016 Elsevier Ltd. All rights reserved.

  17. Apathy Treatment in Alzheimer's Disease: Interim Results of the ASCOMALVA Trial.

    Science.gov (United States)

    Rea, Raffaele; Carotenuto, Anna; Traini, Enea; Fasanaro, Angiola Maria; Manzo, Valentino; Amenta, Francesco

    2015-01-01

    Apathy is a common symptom in Alzheimer's disease (AD), but no treatment has proven to be effective, although administration of cholinesterase inhibitors has been associated with moderate improvements in the short term. This study has compared apathy scores of patients included in "ASCOMALVA" trial treated for two years with donepezil plus a cholinergic precursor (choline alphoscerate), to those of patients receiving donepezil alone with the purpose of assessing if the availability of a higher amount of acetylcholine by combining precursor loading and inhibition of neurotransmitter breakdown would counter apathy in AD. Apathy was measured at baseline and 3, 6, 9, 12, 18, and 24 months using the apathy subtest of the Neuropsychiatric Inventory in 113 mild-moderate AD patients. Two matched groups were compared: group 1 (56 subjects) treated with donepezil plus choline alphoscerate and group 2 (57 subjects) treated with donepezil alone. Frontal functions were explored by the Frontal Assessment Battery (FAB) at baseline. Group 1 subjects showed, as a whole, a lower apathy score after 12 to 24 months. The caregiver distress was descreased after 6 to 24 months. Results were unrelated with cognitive scores measured by the MMSE and ADAS-cog test. Subjects with FAB in the normal range had significantly lower scores. The combination of donepezil with choline alphoscerate is more effective than donepezil alone in countering symptoms of apathy in AD. This suggests that the availability in brain of a higher amount of acetylcholine could affect apathy in AD subjects with spared executive functions.

  18. Operative and conservative management of primary gastric lymphoma: interim results of a German multicenter study

    International Nuclear Information System (INIS)

    Willich, Normann A.; Reinartz, Gabriele; Horst, Ekkehard J.; Delker, Georg; Reers, Berthold; Hiddemann, Wolfgang; Tiemann, Markus; Parwaresch, Reza; Grothaus-Pinke, Bernward; Kocik, Juergen; Koch, Peter

    2000-01-01

    Purpose/Objective: Biology and appropriate management of gastrointestinal (GI) lymphomas are matters of an ongoing controversial debate. To evaluate histological features, sites of involvement and management of primary GI-lymphomas, a prospective multicentric study was initiated in 10/1992. Aim of study was the further standardization of operative and conservative treatment modalities. Materials and Methods: Study started 10/1992 and was closed 11/1996. A total of 381 evaluable patients had been accrued then. Standardized diagnostic workup included endoscopic and radiological evaluation of the complete GI-tract as well as a central histological review. Diagnosis was established after Lewin, stage classification was made after Musshoff, and histological classification was made after Isaacson. Treatment decision concerning operative or conservative management was due to the initially acting physician. Patients with resection of low grade lymphoma received total abdominal irradiation 30 Gy + 10 Gy boost to incompletely resected areas. After resection of high grade lymphoma CHOP chemotherapy (4 cycles for stage IE, 6 cycles for higher stages) after McKelvy was followed by total abdominal irradiation 30 Gy for stage IE respectively involved field irradiation 30 Gy for higher stages with 10 Gy boost to incompletely resected areas. Primary conservative treatment consisted of six cycles COP chemotherapy after Bagley for low grade lymphomas stage >IE and total abdominal irradiation 30 Gy + 10 Gy boost to involved areas for all stages. Patients with high grade lymphomas received 4 x CHOP followed by total abdominal irradiation 30 Gy + 10 Gy boost to involved areas or 6 x CHOP plus involved field radiation therapy with 40 Gy. 257 patients are considered for analysis due to exclusion criteria of the study, 190 of them were suffered from gastric lymphoma. Their median observation time is 29 months, maximum observation time is 68 months. Results: Sites of involvement were

  19. Interim report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1985-06-01

    This Interim Report summarizes the research and development activities of the Superconducting Super Collider project carried out from the completion of the Reference Designs Study (May 1984) to June 1985. It was prepared by the SSC Central Design Group in draft form on the occasion of the DOE Annual Review, June 19--21, 1985. Now largely organized by CDG Divisions, the bulk of each chapter documents the progress and accomplishments to date, while the final section(s) describe plans for future work. Chapter 1, Introduction, provides a basic brief description of the SSC, its physics justification, its origins, and the R&D organization set up to carry out the work. Chapter 2 gives a summary of the main results of the R&D program, the tasks assigned to the four magnet R&D centers, and an overview of the future plans. The reader wishing a quick look at the SSC Phase I effort can skim Chapter 1 and read Chapter 2. Subsequent chapters discuss in more detail the activities on accelerator physics, accelerator systems, magnets and cryostats, injector, detector R&D, conventional facilities, and project planning and management. The magnet chapter (5) documents in text and photographs the impressive progress in successful construction of many model magnets, the development of cryostats with low heat leaks, and the improvement in current-carrying capacity of superconducting strand. Chapter 9 contains the budgets and schedules of the COG Divisions, the overall R&D program, including the laboratories, and also preliminary projections for construction. Appendices provide information on the various panels, task forces and workshops held by the CDG in FY 1985, a bibliography of COG and Laboratory reports on SSC and SSC-related work, and on private industrial involvement in the project.

  20. Deep Vadose Zone Treatability Test for the Hanford Central Plateau. Interim Post-Desiccation Monitoring Results, Fiscal Year 2015

    Energy Technology Data Exchange (ETDEWEB)

    Truex, Michael J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Strickland, Christopher E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Oostrom, Martinus [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Johnson, Christian D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Tartakovsky, Guzel D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Johnson, Timothy C. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Clayton, Ray E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Chronister, Glen B. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-09-01

    A field test of desiccation is being conducted as an element of the Deep Vadose Zone Treatability Test Program. The active desiccation portion of the test has been completed. Monitoring data have been collected at the field test site during the post-desiccation period and are reported herein. This is an interim data summary report that includes about 4 years of post-desiccation monitoring data. The DOE field test plan proscribes a total of 5 years of post-desiccation monitoring.

  1. Choosing or becoming an interim administrator.

    Science.gov (United States)

    Alley, Nancy M

    2005-01-01

    Filling an administrative position on an interim basis requires careful deliberation even when the decision has to be made quickly. A poor fit, even for a short-term position, can lead to problems for the interim administrator, the subsequent permanent administrator, faculty, staff, students, and the nursing program. This article poses questions for decision makers who are contemplating filling a position with an interim appointee. These decision makers must determine the need for an interim administrator, his or her role, the anticipated length of an interim appointment, and whether the interim appointee can apply for the permanent position. In addition, relevant questions are presented for those persons who are considering accepting an interim position, including questions about the position itself and their preparation and personal goals and considerations for leaving the temporary position.

  2. Implant survival after sinus elevation with Straumann(®) BoneCeramic in clinical practice: ad-interim results of a prospective study at a 15-month follow-up.

    Science.gov (United States)

    Covani, Ugo; Orlando, Bruno; Giacomelli, Luca; Cornelini, Roberto; Barone, Antonio

    2011-05-01

    Elevation of the sinus floor with Straumann(®) BoneCeramic gave promising results in some recent clinical studies. However, no study has evaluated the long-term survival of implants after this surgical procedure. We are conducting a prospective, observational study to evaluate the long-term implant survival after this surgical procedure in clinical practice. We present here an ad-interim report of this study, including only patients with ≥12-month follow-up after implant placement. This prospective cohort study will last until a follow-up of 5 years will be achieved in at least 50 patients. Inclusion criteria are: age ≥18 years; presence of a maxillary partial unilateral or bilateral edentulism involving the premolar/molar areas; elective rehabilitation with oral implants; and physical capability to tolerate conventional surgical and restorative procedures. Patients are treated according to the two-stage technique and the preparation is filled with Straumann(®) BoneCeramic. Implant survival is evaluated every 3 months for the first 2 years, and then every 6 months up to 5 years. Fifteen patients are considered in this ad-interim analysis. Mean follow-up was 14.9 ± 3.1 (range: 6-18 months). In total, three implants failed, in one single patient, 6 months after insertion. The cumulative implant survival rate was 92.5% (95% confidence interval: 83.0-100%). This ad-interim analysis suggests that the elevation of the sinus floor with Straumann(®) BoneCeramic may be an effective clinical option over >1-year follow-up. A longer term follow-up will allow a deeper characterization of these preliminary findings. © 2010 John Wiley & Sons A/S.

  3. Interim PET Response-adapted Strategy in Untreated Advanced Stage Hodgkin Lymphoma: Results of GOELAMS LH 2007 Phase 2 Multicentric Trial.

    Science.gov (United States)

    Carras, Sylvain; Dubois, Benjamin; Senecal, Delphine; Jais, Jean-Philippe; Peoc'h, Michel; Quittet, Philippe; Foussard, Charles; Bouabdallah, Krimo; Gastinne, Thomas; Jourdan, Eric; Sanhes, Laurence; Ertault, Marjan; Lamy, Thierry; Molina, Lysiane

    2018-03-01

    Patients with advanced stage Hodgkin lymphoma still present unsatisfactory outcomes. The Groupe d'étude des Leucémies Aigues et des Maladies du Sang (GOELAMS) group conducted a prospective multicentric trial (NCT00920153) for advanced stage Hodgkin lymphoma to evaluate a positron emission tomography (PET)-adapted strategy. Patients received an intensive regimen (VABEM [vindesine, doxorubicin, carmustine, etoposide, and methylprednisolone]) in front-line and interim 18F FDG-PET evaluation after 2 courses (PET-2). Patients with negative PET-2 findings received 1 additional course. Patients with positive PET-2 findings underwent early salvage therapy followed by high-dose therapy/autologous stem cell transplantation. Fifty-one patients were included. The final complete remission rate was 88%. With a median follow up of 5.3 years, 5-year event-free survival and overall survival rates were 75.3% and 85.3%, respectively, for the whole cohort. Patients who were PET-2-negative had 5-year event-free survival and overall survival rates of, respectively, 77.8% and 88.2% versus 85.1% and 91.7% for patients who were PET-2-positive. A PET-guided strategy with early salvage therapy and high-dose therapy/autologous stem cell transplantation for patients with interim PET-2-positive findings is safe and feasible and provide similar outcome as patients with a negative PET-2. Copyright © 2018 Elsevier Inc. All rights reserved.

  4. Presentation of results using the BOST method in food industry

    Directory of Open Access Journals (Sweden)

    Stanisław Borkowski

    2014-10-01

    Full Text Available This paper presents a brief description of the surveyed enterprises and the manufacturing process of its flagship product - butter. Subsequently an analysis of BOST survey results was conducted. The staff spoke out about the importance of factors describing one of Toyota's management principle. Their opinion was the basis for the systematization of research results and to formulate a performance evaluation of the selected company. Results were presented by using spatial charts.

  5. Observational Study of IncobotulinumtoxinA for Cervical Dystonia or Blepharospasm (XCiDaBLE: Interim Results for the First 170 Subjects with Blepharospasm

    Directory of Open Access Journals (Sweden)

    Hubert H. Fernandez

    2014-07-01

    Full Text Available Background: XCiDaBLE is a large, prospective, observational “naturalistic” study evaluating Xeomin® for Cervical Dystonia or BLEpharospasm in the United States. We report the interim results from the blepharospasm cohort of XCiDaBLE.Methods: Subjects (≥18 years old with blepharospasm were followed for two treatment cycles of incobotulinumtoxinA and monitored for 4 weeks after injection via interactive voice/web response system (IVRS/IWRS. The investigator‐reported scale includes the Clinical Global Impression Scale‐Severity subscale (CGI‐S. Patient‐reported outcome measures include the Patient Global Impression Scale‐Severity (PGI‐S and ‐Improvement (PGI‐I subscales, Jankovic Rating Scale (JRS, SF‐12v2® health survey, and Work Productivity and Activity Impairment questionnaire. Subjects are seen by the investigator at baseline (including the first injection, during the second injection, and at a final study visit (12 weeks after the second injection.Results: One hundred seventy subjects were included in this interim analysis. The majority of subjects were female (77.1% and white (91.8%, and had previously been treated with botulinum toxins (96.5%. The mean total dose (both eyes was 71.5 U of incobotulinumtoxinA for the first injection. PGI‐S, PGI‐I, and JRS scores were significantly improved 4 weeks after treatment (all p<0.0001. No differences were noted in either quality of life (QoL or work productivity in this short assessment period. No unexpected adverse events occurred.Discussion: This is an interim study and assessment method based on an IVRS/IWRS. In this predominantly toxin‐experienced cohort, significant benefits in specific and global measures of disease severity were seen in the immediate post‐incobotulinumtoxinA injection period. It will be interesting to see if there are improvements in QoL with consistent individualized injections over a longer period.

  6. Deep Vadose Zone Treatability Test for the Hanford Central Plateau: Interim Post-Desiccation Monitoring Results, Fiscal Year 2014

    Energy Technology Data Exchange (ETDEWEB)

    Truex, Michael J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Strickland, Christopher E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Johnson, Christian D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Johnson, Timothy C. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Clayton, Ray E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Chronister, Glen B. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2014-09-01

    Over decades of operation, the U.S. Department of Energy (DOE) and its predecessors have released nearly 2 trillion L (450 billion gal.) of liquid into the vadose zone at the Hanford Site. Much of this discharge of liquid waste into the vadose zone occurred in the Central Plateau, a 200 km2 (75 mi2) area that includes approximately 800 waste sites. Some of the inorganic and radionuclide contaminants in the deep vadose zone at the Hanford Site are at depths below the limit of direct exposure pathways, but may need to be remediated to protect groundwater. The Tri-Party Agencies (DOE, U.S. Environmental Protection Agency, and Washington State Department of Ecology) established Milestone M 015 50, which directed DOE to submit a treatability test plan for remediation of technetium-99 (Tc-99) and uranium in the deep vadose zone. These contaminants are mobile in the subsurface environment and have been detected at high concentrations deep in the vadose zone, and at some locations have reached groundwater. Testing technologies for remediating Tc-99 and uranium will also provide information relevant for remediating other contaminants in the vadose zone. A field test of desiccation is being conducted as an element of the DOE test plan published in March 2008 to meet Milestone M 015 50. The active desiccation portion of the test has been completed. Monitoring data have been collected at the field test site during the post-desiccation period and are reported herein. This is an interim data summary report that includes about 3 years of post-desiccation monitoring data. The DOE field test plan proscribes a total of 5 years of post-desiccation monitoring.

  7. Prospective Study Evaluating IncobotulinumtoxinA for Cervical Dystonia or Blepharospasm: Interim Results from the First 145 Subjects with Cervical Dystonia

    Directory of Open Access Journals (Sweden)

    Hubert Fernandez

    2013-05-01

    Full Text Available Background: We report the interim results from XCiDaBLE: A large prospective, observational "naturalistic" study evaluating Xeomin® (incobotulinumtoxinA for cervical dystonia or blepharospasm in the United States.Methods: Subjects with CD are followed for 2 treatment cycles and monitored via Interactive Voice/Web Response. Subject-reported scales include the Subject Global Impression-Severity and Improvement; Cervical Dystonia Impact Profile (CDIP-58; and Work Productivity and Quality of Life (QoL are assessed by means of an employment questionnaire and work history and the SF-12v2.Results: This ongoing study includes 145 subjects with a diagnosis of CD. The majority were female (82.3% and White (91.0% and had previously been treated with botulinum toxins (77.2%. There were 106 employed at the time of onset of the disease, but 12.6 years later only 44% were still employed at the time of enrolment into the study and 20% were either receiving or seeking disability benefits. However, only 44% were still employed at the time of recruitment for study participation. The mean total dose/treatment of CD was 225.2 units for the 1st injection. The CDIP-58 total score was significantly improved at four weeks post the first injection compared to baseline (p=<0.0001. Most subjects noted improvement in their global impression assessment. No new or unexpected adverse events occurred. Discussion: The results from these interim analyses confirm previous controlled single-dose studies of incobotulinumtoxinA in terms of efficacy and safety.

  8. On the complementary presentation of results of risk studies

    International Nuclear Information System (INIS)

    Ehrhardt, J.; Bayer, A.

    1983-01-01

    The presentation of the loss of years of life provides the opportunity to illustrate in complementary way the mortality risks evaluated as part of risk studies. As phase A of the DRS (German risk study nuclear power plants) bears upon the results of the American ''Reactor Safety Study'' (WASH 1400) it does not contain that factor of failure which has only been determined in subsequent studies. Phase B intends to present the results of risk assessments increasingly in form of abridged lifetime. (orig.) [de

  9. Effectiveness Monitoring Report, MWMF Tritium Phytoremediation Interim Measures.

    Energy Technology Data Exchange (ETDEWEB)

    Hitchcock, Dan; Blake, John, I.

    2003-02-10

    This report describes and presents the results of monitoring activities during irrigation operations for the calendar year 2001 of the MWMF Interim Measures Tritium Phytoremediation Project. The purpose of this effectiveness monitoring report is to provide the information on instrument performance, analysis of CY2001 measurements, and critical relationships needed to manage irrigation operations, estimate efficiency and validate the water and tritium balance model.

  10. Mass-measurements at GANIL recent results and present developments

    International Nuclear Information System (INIS)

    Mittig, W.

    1992-01-01

    A time of flight together with a magnetic rigidity measurement of fragmentation products was used to get masses of neutron rich nuclei of A = 20 to A = 50 region. Beams of 48 Ca and 64 Ni provided good yields of these nuclei. Results are presented and compared to model predictions. Recently the authors used the second cyclotron of GANIL to measure with high resolution the mass of fusion and deep inelastic reaction products. The method is described and results are shown. Finally extension of this field by the superconducting doublet of solenoids SISSI is described. The possibility of mass-measurements with an Isol+cyclotron device following the GANIL accelerator is discussed

  11. Presenting results of software model checker via debugging interface

    OpenAIRE

    Kohan, Tomáš

    2012-01-01

    Title: Presenting results of software model checker via debugging interface Author: Tomáš Kohan Department: Department of Software Engineering Supervisor of the master thesis: RNDr. Ondřej Šerý, Ph.D., Department of Distributed and Dependable Systems Abstract: This thesis is devoted to design and implementation of the new debugging interface of the Java PathFinder application. As a suitable inte- face container was selected the Eclipse development environment. The created interface should vis...

  12. Interim report on the result of the sodium boiling detection benchmark test using BOR-60 reactor noise data

    International Nuclear Information System (INIS)

    Shinohara, Y.; Watanabe, K.; Hayashi, K.

    1989-01-01

    The present paper deals with the second stage of investigations of acoustic signals from a boiling experiment performed on the KNS I loop at KfK Karlsruhe and first results of analysis of data from a series of boiling experiments carried out in the BOR 60 reactor in the USSR. Signals have been analysed in frequency as well as in time domain. Signal characteristics successfully used to detect the boiling process have been found in time domain. A proposal for in-service boiling monitoring by acoustic means is briefly described. (author). 1 ref., 8 figs, 1 tab

  13. Presentation of search results the CL$_{s}$ technique

    CERN Document Server

    Read, A L

    2002-01-01

    I describe a framework for the presentation of search results which is motivated by frequentist statistics. The most well-known use of this framework is for the combined search for the Higgs boson at LEP. A toy neutrino oscillations experiment is used to illustrate the rich information available in the framework for exclusion and discovery. I argue that the so-called CL/sub s/ technique for setting limits is appropriate for determining exclusion intervals while the determination of confidence intervals advocated by Feldman and Cousins' method is more appropriate for treating established signals, i.e. going beyond discovery to measurement. (17 refs).

  14. Prognostic value of interim FDG PET/CT in Hodgkin's lymphoma patients treated with interim response-adapted strategy: comparison of International Harmonization Project (IHP), Gallamini and London criteria

    Energy Technology Data Exchange (ETDEWEB)

    Le Roux, Pierre-Yves; Querellou, Solene; Salaun, Pierre Yves [University Hospital of Brest, Department of Nuclear Medicine, Brest (France); Gastinne, Thomas; Le Gouill, Steven; Mahe, Beatrice; Dubruille, Viviane; Blin, Nicolas [University Hospital of Nantes, Department of Hematology, Nantes (France); Nowak, Emmanuel [INSERM CIC 05-02 IFR148, Brest (France); Bodet-Milin, Caroline; Bodere-Kraeber, Francoise [University Hospital of Nantes, Department of Nuclear Medicine, Nantes (France)

    2011-06-15

    Interim 2-[{sup 18}F]fluoro-2-deoxy-D-glucose positron emission tomography (FDG PET) has shown to be an accurate predictor of prognosis in Hodgkin's lymphoma (HL). However, FDG PET response criteria are a matter of ongoing debate. The aim of this study was to confirm the prognostic value of interim PET/CT in HL patients treated with an interim response-adapted strategy and to compare the respective performances of different published criteria. Newly diagnosed patients with HL underwent interim PET/CT after four courses of Adriamycin, bleomycin, vinblastine and dacarbazine (ABVD). The treatment strategy was adapted according to prognostic factors at diagnosis and interim PET/CT and CT results. PET images were prospectively interpreted visually: a negative result was defined as no residual uptake above local background. All other findings were considered as positive. Retrospectively, interim PET/CT was analysed according to International Harmonization Project (IHP), Gallamini and London criteria The analysis included 90 patients; 6 of 31 patients with positive interim PET/CT and 7 of 59 patients with negative interim result presented treatment failure. The negative predictive value (NPV) and positive predictive value (PPV) for predicting 2-year progression-free survival (PFS) was 95 and 16%, respectively. With the other criteria, NPV remained very high (from 95 to 96%). The PPV increased from 19 to 45% according to the threshold used. Interim PET/CT was significantly correlated with PFS with Gallamini (p = 0.01) and London criteria (p < 0.0001). Our study confirms the high NPV of interim PET/CT for predicting treatment outcome in HL and a probably better prognostic value using a higher threshold for positivity even after four cycles of chemotherapy as used in Gallamini and London criteria. (orig.)

  15. LHC experiments present new results at Quark Matter 2011 Conference

    CERN Multimedia

    CERN Press Office

    2011-01-01

    The three LHC experiments that study lead ion collisions all presented their latest results today at the annual Quark Matter conference, held this year in Annecy, France. The results are based on analysis of data collected during the last two weeks of the 2010 LHC run, when the LHC switched from protons to lead-ions. All experiments report highly subtle measurements, bringing heavy-ion physics into a new era of high precision studies.   Events recorded by the ALICE experiment from the first lead ion collisions (Nov-Dec 2010). “These results from the LHC lead ion programme are already starting bring new understanding of the primordial universe,” said CERN Director General Rolf Heuer. “The subtleties they are already seeing are very impressive.” In its infancy, just microseconds after the Big Bang, the universe consisted of a plasma of quarks and gluons (QGP), the fundamental building blocks of matter. By colliding heavy ions, physicists can turn back time an...

  16. Interim geotechnical data report

    International Nuclear Information System (INIS)

    1986-01-01

    This issue, the Interim Geotechnical Field Data Report, presents information obtained from the geotechnical activities at the WIPP site underground facilities since the last quarterly report. It also includes cumulative plots which contain all previous data. Finally, it continues the geotechnical analyses and interpretations of the data. The GFDR is organized into two principal parts. The first part, Geotechnical Field Data, presents in graphical form all the data collected since April 1982 from the geomechanical instruments. Presented in the second part, Evaluation and Analyses, are preliminary interpretations and analyses of the data. In this report, continuing geotechnical assessment of all the facility features is presented. Also included in the second part are separate sections on evaluation and interpretation of the instrumentation measurements, and an updated description and evaluation of observed behavior of the underground openings

  17. Interim Results of a Multicenter Trial with the New Electronic Subretinal Implant Alpha AMS in 15 Patients Blind from Inherited Retinal Degenerations.

    Science.gov (United States)

    Stingl, Katarina; Schippert, Ruth; Bartz-Schmidt, Karl U; Besch, Dorothea; Cottriall, Charles L; Edwards, Thomas L; Gekeler, Florian; Greppmaier, Udo; Kiel, Katja; Koitschev, Assen; Kühlewein, Laura; MacLaren, Robert E; Ramsden, James D; Roider, Johann; Rothermel, Albrecht; Sachs, Helmut; Schröder, Greta S; Tode, Jan; Troelenberg, Nicole; Zrenner, Eberhart

    2017-01-01

    Purpose: We assessed the safety and efficacy of a technically advanced subretinal electronic implant, RETINA IMPLANT Alpha AMS, in end stage retinal degeneration in an interim analysis of two ongoing prospective clinical trials. The purpose of this article is to describe the interim functional results (efficacy). Methods: The subretinal visual prosthesis RETINA IMPLANT Alpha AMS (Retina Implant AG, Reutlingen, Germany) was implanted in 15 blind patients with hereditary retinal degenerations at four study sites with a follow-up period of 12 months (www.clinicaltrials.gov NCT01024803 and NCT02720640). Functional outcome measures included (1) screen-based standardized 2- or 4-alternative forced-choice (AFC) tests of light perception, light localization, grating detection (basic grating acuity (BaGA) test), and Landolt C-rings; (2) gray level discrimination; (3) performance during activities of daily living (ADL-table tasks). Results: Implant-mediated light perception was observed in 13/15 patients. During the observation period implant mediated localization of visual targets was possible in 13/15 patients. Correct grating detection was achieved for spatial frequencies of 0.1 cpd (cycles per degree) in 4/15; 0.33 cpd in 3/15; 0.66 cpd in 2/15; 1.0 cpd in 2/15 and 3.3 cpd in 1/15 patients. In two patients visual acuity (VA) assessed with Landolt C- rings was 20/546 and 20/1111. Of 6 possible gray levels on average 4.6 ± 0.8 (mean ± SD, n = 10) were discerned. Improvements (power ON vs. OFF) of ADL table tasks were measured in 13/15 patients. Overall, results were stable during the observation period. Serious adverse events (SAEs) were reported in 4 patients: 2 movements of the implant, readjusted in a second surgery; 4 conjunctival erosion/dehiscence, successfully treated; 1 pain event around the coil, successfully treated; 1 partial reduction of silicone oil tamponade leading to distorted vision (silicon oil successfully refilled). The majority of adverse events (AEs

  18. Interim Results of a Multicenter Trial with the New Electronic Subretinal Implant Alpha AMS in 15 Patients Blind from Inherited Retinal Degenerations

    Directory of Open Access Journals (Sweden)

    Katarina Stingl

    2017-08-01

    Full Text Available Purpose: We assessed the safety and efficacy of a technically advanced subretinal electronic implant, RETINA IMPLANT Alpha AMS, in end stage retinal degeneration in an interim analysis of two ongoing prospective clinical trials. The purpose of this article is to describe the interim functional results (efficacy.Methods: The subretinal visual prosthesis RETINA IMPLANT Alpha AMS (Retina Implant AG, Reutlingen, Germany was implanted in 15 blind patients with hereditary retinal degenerations at four study sites with a follow-up period of 12 months (www.clinicaltrials.gov NCT01024803 and NCT02720640. Functional outcome measures included (1 screen-based standardized 2- or 4-alternative forced-choice (AFC tests of light perception, light localization, grating detection (basic grating acuity (BaGA test, and Landolt C-rings; (2 gray level discrimination; (3 performance during activities of daily living (ADL-table tasks.Results: Implant-mediated light perception was observed in 13/15 patients. During the observation period implant mediated localization of visual targets was possible in 13/15 patients. Correct grating detection was achieved for spatial frequencies of 0.1 cpd (cycles per degree in 4/15; 0.33 cpd in 3/15; 0.66 cpd in 2/15; 1.0 cpd in 2/15 and 3.3 cpd in 1/15 patients. In two patients visual acuity (VA assessed with Landolt C- rings was 20/546 and 20/1111. Of 6 possible gray levels on average 4.6 ± 0.8 (mean ± SD, n = 10 were discerned. Improvements (power ON vs. OFF of ADL table tasks were measured in 13/15 patients. Overall, results were stable during the observation period. Serious adverse events (SAEs were reported in 4 patients: 2 movements of the implant, readjusted in a second surgery; 4 conjunctival erosion/dehiscence, successfully treated; 1 pain event around the coil, successfully treated; 1 partial reduction of silicone oil tamponade leading to distorted vision (silicon oil successfully refilled. The majority of adverse events

  19. A review of proposed Glen Canyon Dam interim operating criteria

    Energy Technology Data Exchange (ETDEWEB)

    LaGory, K.; Hlohowskyj, I.; Tomasko, D.; Hayse, J.; Durham, L.

    1992-04-01

    Three sets of interim operating criteria for Glen Canyon Dam on the Colorado River have been proposed for the period of November 1991, to the completion of the record of decision for the Glen Canyon Dam environmental impact statement (about 1993). These criteria set specific limits on dam releases, including maximum and minimum flows, up-ramp and down-ramp rates, and maximum daily fluctuation. Under the proposed interim criteria, all of these parameters would be reduced relative to historical operating criteria to protect downstream natural resources, including sediment deposits, threatened and endangered fishes, trout, the aquatic food base, and riparian plant communities. The scientific bases of the three sets of proposed operating criteria are evaluated in the present report:(1) criteria proposed by the Research/Scientific Group, associated with the Glen Canyon Environmental Studies (GCES); (2) criteria proposed state and federal officials charged with managing downstream resources; and (3) test criteria imposed from July 1991, to November 1991. Data from Phase 1 of the GCES and other sources established that the targeted natural resources are affected by dam operations, but the specific interim criteria chosen were not supported by any existing studies. It is unlikely that irreversible changes to any of the resources would occur over the interim period if historical operating criteria remained in place. It is likely that adoption of any of the sets of proposed interim operating criteria would reduce the levels of sediment transport and erosion below Glen Canyon Dam; however, these interim criteria could result in some adverse effects, including the accumulation of debris at tributary mouths, a shift of new high-water-zone vegetation into more flood-prone areas, and further declines in vegetation in the old high water zone.

  20. DOE UST interim subsurface barrier technologies workshop

    International Nuclear Information System (INIS)

    1992-09-01

    This document contains information which was presented at a workshop regarding interim subsurface barrier technologies that could be used for underground storage tanks, particularly the tank 241-C-106 at the Hanford Reservation

  1. Psoriasis responds to intralesional injections of alefacept and may predict systemic response to intramuscular alefacept: interim results of a single-arm, open-label study.

    Science.gov (United States)

    Gattu, Shilpa; Busse, Kristine; Bhutani, Tina; Chiang, Charles; Nguyen, Thao; Becker, Emily; Koo, John Y M

    2012-04-01

    Alefacept is a remittive treatment for generalized psoriasis but is rarely used due to its erratic efficacy. To determine if psoriasis plaques will respond to intralesional alefacept and if this predicts a systemic response to intramuscular (IM) alefacept. We describe a 25-week, single-center, open-label study. Patients received weekly intralesional alefacept of increasing concentrations into target plaques for 3 weeks followed by IM injections for 12 weeks and concluded with an observation period of 9 weeks. The psoriasis area and severity index (PASI) was used to assess the efficacy of IM alefacept. Interim results are reported for the first seven patients enrolled. Two patients responded intralesionally to the most dilute 1:100 concentration of alefacept to sterile water and achieved a 59% and 100% improvement in PASI. Five patients did not respond intralesionally to the most dilute form of alefacept and none achieved PASI 75. Two of these five patients did not respond to any concentration and achieved a 26% and 38% improvement in PASI. Limitations to this study include a small sample size and being non-placebo-controlled. Alefacept is effective intralesionally and may predict a systemic response - challenging the concept that biologics must work systemically.

  2. The DIVA programme: General presentation and first results

    International Nuclear Information System (INIS)

    Dumaz, P.; Duc, B.

    2000-01-01

    The French 'Commissariat a I'Energie Atomique' (CEA/DRN, Nuclear Reactor Division) is carrying out a new programme devoted to the thermal-hydraulics of steam injectors. This programme was called DIVA. Both experimental and theoretical works are planned. Motivations, objectives, test facility and test section dimensioning of this new programme are presented. A first test series was just performed. The validation of the test section dimensioning and experimental procedures was obtained. These first experimental data are presented and preliminary analyses are given. (author)

  3. Internal Revenue Service: Assessment of Budget Request for Fiscal Year 2003 and Interim Results of 2002 Tax Filing Season

    National Research Council Canada - National Science Library

    White, James

    2002-01-01

    ...) and the 2002 tax filing season. As you requested, our statement assesses the support for various aspects of IRS s budget request, including the linkage between resources requested and expected results, and IRS's performance...

  4. Interim recommendations concerning the risks to the Dutch population resulting from the use of radioactive wastes in building materials

    International Nuclear Information System (INIS)

    1985-01-01

    The present report, drawn up at the request of the former Minister of Public Health and Environmental Affairs, discusses the potential radiological consequences for the population of the Netherlands of using waste materials as building materials in housing construction. In his request the Minister points to the growing need to use various waste products as building materials. The highest increase of the effective dose equivalent for the foreseeable use of waste products in building construction implies that the annual exposure, averaged over the entire population, could eventually be increased by a maximum of 0.05 mSv per caput. (Auth.)

  5. Design, methods, baseline characteristics and interim results of the Catheter Sampled Blood Archive in Cardiovascular Diseases (CASABLANCA study

    Directory of Open Access Journals (Sweden)

    Hanna K. Gaggin

    2014-11-01

    Conclusions: The CASABLANCA study will examine the role of novel biomarkers and metabolomics for predicting a wide range of cardiovascular, neurologic, and renal complications in patients undergoing angiography. Full results are expected in the latter half of 2014 (ClinicalTrials.Gov # NCT00842868.

  6. Presentation of the 1998 financial results of the Framatome group

    International Nuclear Information System (INIS)

    Vignon, D.

    1999-01-01

    This document makes a statement of the activity of the Framatome group during the year 1998. The activities of the group are shared into two main sectors of comparable size: the energy sector (nuclear fuels, nuclear realizations, nuclear services and industrial equipments) and the connectors engineering sector (electronics, electricity, automotive industry, interconnections and microelectronics). The financial results show an important growth of the connectors engineering sector while the energy sector remained satisfactory. Results are detailed by sector and activity: energy (realizations and nuclear equipments, nuclear services, nuclear fuels and industrial equipments), connectors engineering, and research and development activity of the group. (J.S.)

  7. Randomized Controlled Trial of Forward-Planned Intensity Modulated Radiotherapy for Early Breast Cancer: Interim Results at 2 Years

    International Nuclear Information System (INIS)

    Barnett, Gillian C.; Wilkinson, Jennifer S.; Moody, Anne M.; Wilson, Charles B.; Twyman, Nicola; Wishart, Gordon C.; Burnet, Neil G.; Coles, Charlotte E.

    2012-01-01

    Purpose: This single-center randomized trial was designed to investigate whether intensity-modulated radiotherapy (IMRT) reduces late toxicity in patients with early-stage breast cancer. Methods and Materials: The standard tangential plans of 1,145 nonselected patients were analyzed. The patients with inhomogeneous plans were randomized to a simple method of forward-planned IMRT or standard radiotherapy (RT). The primary endpoint was serial photographic assessment of breast shrinkage. Results: At 2 years, no significant difference was found in the development of any photographically assessed breast shrinkage between the patients randomized to the interventional or control group (odds ratio, 1.51; 95% confidence interval, 0.83–1.58; p = .41). The patients in the control group were more likely to develop telangiectasia than those in the IMRT group (odds ratio, 1.68; 95% confidence interval 1.13–2.40; p = .009). Poor baseline surgical cosmesis resulted in poor overall cosmesis at 2 years after RT. In patients who had good surgical cosmesis, those randomized to IMRT were less likely to deteriorate to a moderate or poor overall cosmesis than those in the control group (odds ratio, 0.63; 95% confidence interval, 0.39–1.03, p = .061). Conclusions: IMRT can lead to a significant reduction in telangiectasia at comparatively early follow-up of only 2 years after RT completion. An important component of breast induration and shrinkage will actually result from the surgery and not from the RT. Surgical cosmesis is an important determinant of overall cosmesis and could partially mask the longer term benefits of IMRT at this early stage.

  8. Short implants in maxillary and mandibular rehabilitations: interim results (6 to 42 months) of a prospective study.

    Science.gov (United States)

    Taschieri, Silvio; Corbella, Stefano; Molinari, Raffaella; Saita, Massimo; Del Fabbro, Massimo

    2015-02-01

    The aim of this single-cohort study was to evaluate clinical survival and success of partial rehabilitation supported by reduced-length implants in maxilla and mandible. Data from 53 short implants placed in 41 patients are presented. Before surgery mean residual bone height was 6.21 ± 1.05 mm in the upper jaw and 10.73 ± 1.63 mm in the mandible. None of the implants failed, and the cumulative survival rate was 100% at 1 year after prosthetic loading. Mean peri-implant bone loss was 0.69 ± 0.24 mm for maxillary implants and 0.73 ± 0.23 mm for mandibular implants, and there was no significant difference between the 2 jaws. No complications were recorded. Despite the limitations of this study concerning study design and sample size, short implants may be considered effective in supporting partial rehabilitation in both maxilla and mandible. More well-designed studies with a larger sample size and longer follow-up are needed to validate the use of short implants.

  9. Presentation of RTE results 2003; Bilan electrique francais 2003

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    In 2003, RTE recorded a clear improvement in its financial results, and continued its debt reduction programme. The financial year 2003 was marked by a clear improvement in RTE's financial performance: results exceeded objectives, with turnover growing strongly, net income reached levels almost three times higher than those recorded in 2002, the economic rate of return rose to 7.1%, and debt was reduced by 470 Meuros. These results are explained by the substantial improvement in productivity, which has risen by 5% per year on average over the last three years. Net income has almost tripled due to RTE's improved productivity completed by a significant rise in its turnover and stabilizing operating costs RTE's finances therefore remain healthy, enabling the company to continue its debt reduction programme. Satisfactory economic and financial rates of return. Deadlines facing RTE in 2004: in application of the second European Directive, adopted on 26 June 2003, RTE faces two major deadlines in 2004: - the implementation of the 2. phase in the process of opening up the French electricity market, - its legal independence. On 1 July 2004, the market will be opened up to competition for all professional customers. At that date RTE, like all other electricity transmission system operators (TSOs) in the European Union, should be a legally independent body. The new central role of TSOs in Europe: how are electricity transmission system operators in other EU countries organised?.

  10. Bronchial obstruction syndrome as a predictor of mortality in cardiac surgery: interim results of prospective cohort study

    Directory of Open Access Journals (Sweden)

    Д. Н. Пономарев

    2016-01-01

    Full Text Available Objective. To investigate the effect of bronchial obstruction syndrome on perioperative characteristics in patients undergoing coronary artery bypass grafting (CABG.Methods. Body plethysmography and spiroergometry at rest were used to study respiratory function and consumption of O2. To evaluate the effectiveness of pulmonary ventilation, the oxygen utilization coefficient of (O2CU was calculated in 178 patients prior to scheduled surgery. The relationship of external ventilation parameters and perioperative clinical characteristics was analyzed. Results. A bronchial obstruction syndrome was detected in 30 (16.9% patients, with 21 (11.2% of them having no chronic obstructive pulmonary disease diagnosis. 4 patients (2.3% with obstructive pulmonary disease had no bronchial obstruction. Thus, chronic obstructive pulmonary disease was misdiagnosed in 13.5% cases. In patients undergoing isolated CABG, negative relationship was revealed between the Tiffno index and hospital stay (regression coefficient –6.9, 95%, confidence interval –14.4… 0.6; p = 0.07. In patients operated with the myocardium stabilized, bimammary grafting tended to increase hospital stay by an average of 4.3 days (95% CI 1.5–7.1; p=0.003. The majority of patients had a low O2CU. O2CU lower than 16.2 ml/l is associated with an increased risk of postoperative atrial fibrillation (AF in the postoperative period (OR 2.96; 95% CI 1.01–9.83; p = 0.04. No significant associations were observed between the degree of bronchial obstruction and the number of perioperative complications. Conclusion. The degree of bronchial obstruction could be positively associated with the length of hospital stay. A critically low level of O2CU is explained by an increased risk of postoperative AF. Further research might result in the identification of predictors for respiratory complications and long-term mortality in patients after CABG.

  11. Phase 2 clinical trial of a recombinant adeno-associated viral vector expressing α1-antitrypsin: interim results.

    Science.gov (United States)

    Flotte, Terence R; Trapnell, Bruce C; Humphries, Margaret; Carey, Brenna; Calcedo, Roberto; Rouhani, Farshid; Campbell-Thompson, Martha; Yachnis, Anthony T; Sandhaus, Robert A; McElvaney, Noel G; Mueller, Christian; Messina, Louis M; Wilson, James M; Brantly, Mark; Knop, David R; Ye, Guo-jie; Chulay, Jeffrey D

    2011-10-01

    Recombinant adeno-associated virus (rAAV) vectors offer promise for the gene therapy of α(1)-antitrypsin (AAT) deficiency. In our prior trial, an rAAV vector expressing human AAT (rAAV1-CB-hAAT) provided sustained, vector-derived AAT expression for >1 year. In the current phase 2 clinical trial, this same vector, produced by a herpes simplex virus complementation method, was administered to nine AAT-deficient individuals by intramuscular injection at doses of 6.0×10(11), 1.9×10(12), and 6.0×10(12) vector genomes/kg (n=3 subjects/dose). Vector-derived expression of normal (M-type) AAT in serum was dose dependent, peaked on day 30, and persisted for at least 90 days. Vector administration was well tolerated, with only mild injection site reactions and no serious adverse events. Serum creatine kinase was transiently elevated on day 30 in five of six subjects in the two higher dose groups and normalized by day 45. As expected, all subjects developed anti-AAV antibodies and interferon-γ enzyme-linked immunospot responses to AAV peptides, and no subjects developed antibodies to AAT. One subject in the mid-dose group developed T cell responses to a single AAT peptide unassociated with any clinical effects. Muscle biopsies obtained on day 90 showed strong immunostaining for AAT and moderate to marked inflammatory cell infiltrates composed primarily of CD3-reactive T lymphocytes that were primarily of the CD8(+) subtype. These results support the feasibility and safety of AAV gene therapy for AAT deficiency, and indicate that serum levels of vector-derived normal human AAT >20 μg/ml can be achieved. However, further improvements in the design or delivery of rAAV-AAT vectors will be required to achieve therapeutic target serum AAT concentrations.

  12. Toward harmonized phenotyping of human myeloid-derived suppressor cells by flow cytometry: results from an interim study.

    Science.gov (United States)

    Mandruzzato, Susanna; Brandau, Sven; Britten, Cedrik M; Bronte, Vincenzo; Damuzzo, Vera; Gouttefangeas, Cécile; Maurer, Dominik; Ottensmeier, Christian; van der Burg, Sjoerd H; Welters, Marij J P; Walter, Steffen

    2016-02-01

    There is an increasing interest for monitoring circulating myeloid-derived suppressor cells (MDSCs) in cancer patients, but there are also divergences in their phenotypic definition. To overcome this obstacle, the Cancer Immunoguiding Program under the umbrella of the Association of Cancer Immunotherapy is coordinating a proficiency panel program that aims at harmonizing MDSC phenotyping. After a consultation period, a two-stage approach was designed to harmonize MDSC phenotype. In the first step, an international consortium of 23 laboratories immunophenotyped 10 putative MDSC subsets on pretested, peripheral blood mononuclear cells of healthy donors to assess the level of concordance and define robust marker combinations for the identification of circulating MDSCs. At this stage, no mandatory requirements to standardize reagents or protocols were introduced. Data analysis revealed a small intra-laboratory, but very high inter-laboratory variance for all MDSC subsets, especially for the granulocytic subsets. In particular, the use of a dead-cell marker altered significantly the reported percentage of granulocytic MDSCs, confirming that these cells are especially sensitive to cryopreservation and/or thawing. Importantly, the gating strategy was heterogeneous and associated with high inter-center variance. Overall, our results document the high variability in MDSC phenotyping in the multicenter setting if no harmonization/standardization measures are applied. Although the observed variability depended on a number of identified parameters, the main parameter associated with variation was the gating strategy. Based on these findings, we propose further efforts to harmonize marker combinations and gating parameters to identify strategies for a robust enumeration of MDSC subsets.

  13. Phase 2 clinical trial of a recombinant adeno-associated viral vector expressing α1-antitrypsin: interim results.

    LENUS (Irish Health Repository)

    Flotte, Terence R

    2011-10-01

    Recombinant adeno-associated virus (rAAV) vectors offer promise for the gene therapy of α(1)-antitrypsin (AAT) deficiency. In our prior trial, an rAAV vector expressing human AAT (rAAV1-CB-hAAT) provided sustained, vector-derived AAT expression for >1 year. In the current phase 2 clinical trial, this same vector, produced by a herpes simplex virus complementation method, was administered to nine AAT-deficient individuals by intramuscular injection at doses of 6.0×10(11), 1.9×10(12), and 6.0×10(12) vector genomes\\/kg (n=3 subjects\\/dose). Vector-derived expression of normal (M-type) AAT in serum was dose dependent, peaked on day 30, and persisted for at least 90 days. Vector administration was well tolerated, with only mild injection site reactions and no serious adverse events. Serum creatine kinase was transiently elevated on day 30 in five of six subjects in the two higher dose groups and normalized by day 45. As expected, all subjects developed anti-AAV antibodies and interferon-γ enzyme-linked immunospot responses to AAV peptides, and no subjects developed antibodies to AAT. One subject in the mid-dose group developed T cell responses to a single AAT peptide unassociated with any clinical effects. Muscle biopsies obtained on day 90 showed strong immunostaining for AAT and moderate to marked inflammatory cell infiltrates composed primarily of CD3-reactive T lymphocytes that were primarily of the CD8(+) subtype. These results support the feasibility and safety of AAV gene therapy for AAT deficiency, and indicate that serum levels of vector-derived normal human AAT >20 μg\\/ml can be achieved. However, further improvements in the design or delivery of rAAV-AAT vectors will be required to achieve therapeutic target serum AAT concentrations.

  14. Extraarticular subtalar arthrodesis for pes planovalgus: an interim result of 50 feet in patients with spastic diplegia.

    Science.gov (United States)

    Yoon, Hong Ki; Park, Kun Bo; Roh, Jae Young; Park, Hui Wan; Chi, Hye Jin; Kim, Hyun Woo

    2010-03-01

    There are no reports of the pressure changes across the foot after extraarticular subtalar arthrodesis for a planovalgus foot deformity in cerebral palsy. This paper reviews our results of extraarticular subtalar arthrodesis using a cannulated screw and cancellous bone graft. Fifty planovalgus feet in 30 patients with spastic diplegia were included. The mean age at the time of surgery was 9 years, and the mean follow-up period was 3 years. The radiographic, gait, and dynamic foot pressure changes after surgery were investigated. All patients showed union and no recurrence of the deformity. Correction of the abduction of the forefoot, subluxation of the talonavicular joint, and the hindfoot valgus was confirmed radiographically. However, the calcaneal pitch was not improved significantly after surgery. Peak dorsiflexion of the ankle during the stance phase was increased after surgery, and the peak plantarflexion at push off was decreased. The peak ankle plantar flexion moment and power were also decreased. Postoperative elevation of the medial longitudinal arch was expressed as a decreased relative vertical impulse of the medial midfoot and an increased relative vertical impulse (RVI) of the lateral midfoot. However, the lower than normal RVI of the 1st and 2nd metatarsal head after surgery suggested uncorrected forefoot supination. The anteroposterior and lateral paths of the center of pressure were improved postoperatively. Our experience suggests that the index operation reliably corrects the hindfoot valgus in patients with spastic diplegia. Although the operation corrects the plantar flexion of the talus, it does not necessarily correct the plantarflexed calcaneus and forefoot supination. However, these findings are short-term and longer term observations will be needed.

  15. Detection of mammaglobin mRNA in peripheral blood is associated with high grade breast cancer: Interim results of a prospective cohort study

    Directory of Open Access Journals (Sweden)

    Schutte Del H

    2008-02-01

    Full Text Available Abstract Background We sought to examine the detection rate of cancer cells in peripheral blood (PBL and in bone marrow (BM using an established 7-gene marker panel and evaluated whether there were any definable associations of any individual gene with traditional predictors of prognosis. Methods Patients with T1-T3 primary breast cancer were enrolled into a prospective, multi-institutional cohort study. In this interim analysis 215 PBL and 177 BM samples were analyzed by multimarker, real-time RT-PCR analysis designed to detect circulating and disseminated breast cancer cells. Results At a threshold of three standard deviations from the mean expression level of normal controls, 63% (136/215 of PBL and 11% (19/177 of BM samples were positive for at least one cancer-associated marker. Marker positivity in PBL demonstrated a statistically significant association with grade II-III (vs. grade I; p = 0.0083. Overexpression of the mammaglobin (mam gene alone had a statistically significant association with high tumor grade (p = 0.0315, and showed a trend towards ER-negative tumors and a high risk category. There was no association between marker positivity in PBL and the pathologic (H&E and/or molecular (RT-PCR status of the axillary lymph nodes (ALN. Conclusion This study suggests that molecular detection of circulating cancer cells in PBL detected by RT-PCR is associated with high tumor grade and specifically that overexpression of the mam gene in PBL may be a poor prognostic indicator. There was no statistically significant association between overexpression of cancer-associated genes in PBL and ALN status, supporting the concept of two potentially separate metastatic pathways.

  16. Long-term efficacy and safety of mipomersen in patients with familial hypercholesterolaemia: 2-year interim results of an open-label extension

    Science.gov (United States)

    Santos, Raul D.; Duell, P. Barton; East, Cara; Guyton, John R.; Moriarty, Patrick M.; Chin, Wai; Mittleman, Robert S.

    2015-01-01

    Aims To evaluate the efficacy and safety of extended dosing with mipomersen in patients with familial hypercholesterolaemia (HC) taking maximally tolerated lipid-lowering therapy. Methods and results A planned interim analysis of an ongoing, open-label extension trial in patients (n = 141) with familial HC receiving a subcutaneous injection of 200 mg mipomersen weekly plus maximally tolerated lipid-lowering therapy for up to 104 weeks. The mean changes in low-density lipoprotein cholesterol (LDL-C) from baseline to weeks 26 (n = 130), 52 (n = 111), 76 (n = 66), and 104 (n = 53) were −28, −27, −27, and −28%; and in apolipoprotein B −29, −28, −30, and −31%, respectively. Reductions in total cholesterol, non-high-density lipoprotein-cholesterol, and lipoprotein(a) were comparable with decreases in LDL-C and apolipoprotein B levels. Mean high-density lipoprotein cholesterol increased from baseline by 7 and 6% at weeks 26 and 52, respectively. The long-term safety profile of mipomersen was similar to that reported in the associated randomized placebo-controlled Phase 3 trials. Adverse events included injection site reactions and flu-like symptoms. There was an incremental increase in the median liver fat during the initial 6–12 months that appeared to diminish with continued mipomersen exposure beyond 1 year and returned towards baseline 24 weeks after last drug dose suggestive of adaptation. The median alanine aminotransferase level showed a similar trend over time. Conclusion Long-term treatment with mipomersen for up to 104 weeks provided sustained reductions in all atherosclerotic lipoproteins measured and a safety profile consistent with prior controlled trials in these high-risk patient populations. Clinicaltrials.gov NCT00694109. PMID:24366918

  17. A multicenter prospective study of patients undergoing open ventral hernia repair with intraperitoneal positioning using the monofilament polyester composite ventral patch: interim results of the PANACEA study.

    Science.gov (United States)

    Berrevoet, Frederik; Doerhoff, Carl; Muysoms, Filip; Hopson, Steven; Muzi, Marco Gallinella; Nienhuijs, Simon; Kullman, Eric; Tollens, Tim; Schwartz, Mark R; LeBlanc, Karl; Velanovich, Vic; Jørgensen, Lars Nannestad

    2017-01-01

    This study assessed the recurrence rate and other safety and efficacy parameters following ventral hernia repair with a polyester composite prosthesis (Parietex™ Composite Ventral Patch [PCO-VP]). A single-arm, multicenter prospective study of 126 patients undergoing open ventral hernia repair with the PCO-VP was performed. Patient outcomes were assessed at discharge and at 10 days, 1, 6, 12, and 24 months postoperative. All patients had hernioplasty for umbilical (n = 110, 87.3%) or epigastric hernia (n = 16, 12.7%). Mean hernia diameter was 1.8 ± 0.8 cm. Mean operative time was 36.2 ±15.6 minutes, with a mean mesh positioning time of 8.1 ± 3.4 minutes. Surgeons reported satisfaction with mesh ease of use in 95% of surgeries. The cumulative hernia recurrence rate at 1 year was 2.8% (3/106). Numeric Rating Scale (NRS) pain scores showed improvement from 2.1 ± 2.0 at preoperative baseline to 0.5 ± 0.7 at 1 month postoperative ( P < 0.001), and this low pain level was maintained at 12 months postsurgery ( P < 0.001). The mean global Carolina's Comfort Scale ® (CCS) score improved postoperatively from 3.8 ± 6.2 at 1 month to 1.6 ± 3.5 at 6 months ( P < 0.001). One patient was unsatisfied with the procedure. This 1-year interim analysis using PCO-VP for primary umbilical and epigastric defects shows promising results in terms of mesh ease of use, postoperative pain, and patient satisfaction. Recurrence rate is low, but, as laparoscopic evaluation shows a need for patch repositioning in some cases, an accurate surgical technique remains of utmost importance.

  18. Presentation of RTE results 2003; Presentation des resultats 2003 de RTE

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    For RTE, the financial year 2003 was marked by a number of achievements: our financial performances registered a clear improvement, above objectives, with turnover growing strongly; net income reached levels almost three times higher than those recorded in 2002; the economic rate of return rose to 7.1%; and debt was reduced by 470 Meuros. These results are explained by the substantial improvement in productivity, which has risen by 5% per year on average over the last three years.

  19. Interim Results from a Study of the Impacts of Tin (II) Based Mercury Treatment in a Small Stream Ecosystem: Tims Branch, Savannah River Site

    Energy Technology Data Exchange (ETDEWEB)

    Looney, Brian [Savannah River National Laboratory (SRNL); BryanJr., Larry [Savannah River Ecology Laboratory; Mathews, Teresa J [ORNL; Peterson, Mark J [ORNL; Roy, W Kelly [ORNL; Jett, Robert T [ORNL; Smith, John G [ORNL

    2012-03-01

    A research team is assessing the impacts of an innovative mercury treatment system in Tims Branch, a small southeastern stream. The treatment system, installed in 2007, reduces and removes inorganic mercury from water using tin(II) (stannous) chloride addition followed by air stripping. The system results in discharge of inorganic tin to the ecosystem. This screening study is based on historical information combined with measurements of contaminant concentrations in water, fish, sediment, biofilms and invertebrates. Initial mercury data indicate that first few years of mercury treatment resulted in a significant decrease in mercury concentration in an upper trophic level fish, redfin pickerel, at all sampling locations in the impacted reach. For example, the whole body mercury concentration in redfin pickerel collected from the most impacted pond decreased approximately 72% between 2006 (pre-treatment) and 2010 (post-treatment). Over this same period, mercury concentrations in the fillet of redfin pickerel in this pond were estimated to have decreased from approximately 1.45 {micro}g/g (wet weight basis) to 0.45 {micro}g/g - a decrease from 4.8x to 1.5x the current EPA guideline concentration for mercury in fillet (0.3 {micro}g/g). Thermodynamic modeling, scanning electron microscopy, and other sampling data for tin suggest that particulate tin (IV) oxides are a significant geochemical species entering the ecosystem with elevated levels of tin measured in surficial sediments and biofilms. Detectable increases in tin in sediments and biofilms extended approximately 3km from the discharge location. Tin oxides are recalcitrant solids that are relatively non-toxic and resistant to dissolution. Work continues to develop and validate methods to analyze total tin in the collected biota samples. In general, the interim results of this screening study suggest that the treatment process has performed as predicted and that the concentration of mercury in upper trophic level

  20. Our path to the 21{sup st} century. Interim result for the environmental and energy policy; Unser Weg in das 21. Jahrhundert. Zwischenbilanz der Umwelt- und Energiepolitik

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-12-15

    A future-oriented society needs a close connection between ecology and economy, if it should show solidarity. It is about growth which no longer is linked to an excessive consumption of natural resources. Instead, climate and natural resources shall be conserved. A gain in quality of life shall be enabled. This fundamental transformation process is a key target of the Federal Republic of Germany. Under this aspect, the contribution under consideration supplies an interim balance of the environmental policy and energy policy.

  1. The Interim Financial Statements: The Case of Greece

    OpenAIRE

    Rogdaki, E.I.; Kazantzis, Ch.

    1999-01-01

    The following paper refers to the accounting and auditing issues which emerge in the preparation of the interim financial statements of the companies: Firstly, the interim financial statements are defined as being the financial statements that provide useful information about the financial position and the financial results of a company which are realized and accrued during the fiscal year. The interim financial statements can be prepared on a monthly basis, on a quarterly basis or covering a...

  2. ITER Conceptual design: Interim report

    International Nuclear Information System (INIS)

    1990-01-01

    This interim report describes the results of the International Thermonuclear Experimental Reactor (ITER) Conceptual Design Activities after the first year of design following the selection of the ITER concept in the autumn of 1988. Using the concept definition as the basis for conceptual design, the Design Phase has been underway since October 1988, and will be completed at the end of 1990, at which time a final report will be issued. This interim report includes an executive summary of ITER activities, a description of the ITER device and facility, an operation and research program summary, and a description of the physics and engineering design bases. Included are preliminary cost estimates and schedule for completion of the project

  3. EMCS Retrofit Analysis - Interim Report

    Energy Technology Data Exchange (ETDEWEB)

    Diamond, R.C.; Salsbury, T.I.; Bell, G.C.; Huang, Y.J.; Sezgen, A.O.; Mazzucchi, R.; Romberger, J.

    1999-03-01

    This report presents the interim results of analyses carried out in the Phillip Burton Federal Building in San Francisco from 1996 to 1998. The building is the site of a major demonstration of the BACnet communication protocol. The energy management and control systems (EMCS) in the building were retrofitted with BACnet compatible controllers in order to integrate certain existing systems on one common network. In this respect, the project has been a success. Interoperability of control equipment from different manufacturers has been demonstrated in a real world environment. Besides demonstrating interoperability, the retrofits carried out in the building were also intended to enhance control strategies and capabilities, and to produce energy savings. This report presents analyses of the energy usage of HVAC systems in the building, control performance, and the reaction of the building operators. The report does not present an evaluation of the performance capabilities of the BACnet protocol. A monitoring system was installed in the building that parallels many of the EMCS sensors and data were archived over a three-year period. The authors defined pre-retrofit and post-retrofit periods and analyzed the corresponding data to establish the changes in building performance resulting from the retrofit activities. The authors also used whole-building energy simulation (DOE-2) as a tool for evaluating the effect of the retrofit changes. The results of the simulation were compared with the monitored data. Changes in operator behavior were assessed qualitatively with questionnaires. The report summarizes the findings of the analyses and makes several recommendations as to how to achieve better performance. They maintain that the full potential of the EMCS and associated systems is not being realized. The reasons for this are discussed along with possible ways of addressing this problem. They also describe a number of new technologies that could benefit systems of the type

  4. Interim Design Report

    CERN Document Server

    Choubey, S.; Goswami, S.; Berg, J.S.; Fernow, R.; Gallardo, J.C.; Gupta, R.; Kirk, H.; Simos, N.; Souchlas, N.; Ellis, M.; Kyberd, P.; Benedetto, E.; Fernandez-Martinez, E.; Efthymiopoulos, I.; Garoby, R.; Gilardoni, S.; Martini, M.; Prior, G.; Ballett, P.; Pascoli, S.; Bross, A.; Geer, S.; Johnstone, C.; Kopp, J.; Mokhov, N.; Morfin, J.; Neuffer, D.; Parke, S.; Popovic, M.; Strait, J.; Striganov, S.; Blondel, A.; Dufour, F.; Laing, A.; Soler, F.J.P; Lindner, M.; Schwetz, T.; Alekou, A.; Apollonio, M.; Aslaninejad, M.; Bontoiu, C.; Dornan, P.; Eccleston, R.; Kurup, A.; Long, K.; Pasternak, J.; Pozimski, J.; Bogacz, A.; Morozov, V.; Roblin, Y.; Bhattacharya, S.; Majumdar, D.; Mori, Y.; Planche, T.; Zisman, M.; Cline, D.; Stratakis, D.; Ding, X.; Coloma, P.; Donini, A.; Gavela, B.; Lopez Pavon, J.; Maltoni, M.; Bromberg, C.; Bonesini, M.; Hart, T.; Kudenko, Y.; Mondal, N.; Antusch, S.; Blennow, M.; Ota, T.; Abrams, R.J.; Ankenbrandt, C.M.; Beard, K.B.; Cummings, M.A.C.; Flanagan, G.; Johnson, R.P.; Roberts, T.J.; Yoshikawa, C.Y.; Migliozzi, P.; Palladino, V.; de Gouvea, A.; Graves, V.B.; Kuno, Y.; Peltoniemi, J.; Blackmore, V.; Cobb, J.; Witte, H.; Mezzetto, M.; Rigolin, S.; McDonald, K.T.; Coney, L.; Hanson, G.; Snopok, P.; Tortora, L.; Andreopoulos, C.; Bennett, J.R.J.; Brooks, S.; Caretta, O.; Davenne, T.; Densham, C.; Edgecock, R.; Kelliher, D.; Loveridge, P.; McFarland, A.; Machida, S.; Prior, C.; Rees, G.; Rogers, C.; Thomason, J.W.G.; Booth, C.; Skoro, G.; Karadzhov, Y.; Matev, R.; Tsenov, R.; Samulyak, R.; Mishra, S.R.; Petti, R.; Dracos, M.; Yasuda, O.; Agarwalla, S.K.; Cervera-Villanueva, A.; Gomez-Cadenas, J.J.; Hernandez, P.; Li, T.; Martin-Albo, J.; Huber, P.; Back, J.; Barker, G.; Harrison, P.; Meloni, D.; Tang, J.; Winter, W.

    2011-01-01

    The International Design Study for the Neutrino Factory (the IDS-NF) was established by the community at the ninth "International Workshop on Neutrino Factories, super-beams, and beta- beams" which was held in Okayama in August 2007. The IDS-NF mandate is to deliver the Reference Design Report (RDR) for the facility on the timescale of 2012/13. In addition, the mandate for the study [3] requires an Interim Design Report to be delivered midway through the project as a step on the way to the RDR. This document, the IDR, has two functions: it marks the point in the IDS-NF at which the emphasis turns to the engineering studies required to deliver the RDR and it documents baseline concepts for the accelerator complex, the neutrino detectors, and the instrumentation systems. The IDS-NF is, in essence, a site-independent study. Example sites, CERN, FNAL, and RAL, have been identified to allow site-specific issues to be addressed in the cost analysis that will be presented in the RDR. The choice of example sites shou...

  5. A multicenter prospective study of patients undergoing open ventral hernia repair with intraperitoneal positioning using themonofilament polyester composite ventral patch: interim results of the PANACEA study

    Directory of Open Access Journals (Sweden)

    Berrevoet F

    2017-05-01

    month postoperative (P < 0.001, and this low pain level was maintained at 12 months postsurgery (P < 0.001. The mean global Carolina’s Comfort Scale® (CCS score improved postoperatively from 3.8 ± 6.2 at 1 month to 1.6 ± 3.5 at 6 months (P < 0.001. One patient was unsatisfied with the procedure.Conclusion: This 1-year interim analysis using PCO-VP for primary umbilical and epigastric defects shows promising results in terms of mesh ease of use, postoperative pain, and patient satisfaction. Recurrence rate is low, but, as laparoscopic evaluation shows a need for patch repositioning in some cases, an accurate surgical technique remains of utmost importance. Keywords: intraperitoneal mesh, epigastric hernia, umbilical hernia, pain

  6. Early rehabilitation of facial defects using interim removable prostheses: A clinical case report

    Directory of Open Access Journals (Sweden)

    Vivekanandhan Ramkumar

    2013-01-01

    Full Text Available Surgical resection of neoplasms or malformations of the face may result in defects that are not amenable to immediate surgical reconstruction. Such defects can have a severe adverse effect on patient perceptions of body image and self-esteem. In these cases, the use of an interim removable facial prosthesis can offer a rapid alternative treatment solution. The patient may then resume social interactions more comfortably while permitting easy access to the facial defect to observe tissue healing while awaiting definitive rehabilitation. This article presents a case report describing the use of interim nasal prostheses to provide rapid patient rehabilitation of facial defects.

  7. Presentations

    International Nuclear Information System (INIS)

    2007-01-01

    The PARIS meeting held in Cracow, Poland from 14 to 15 May 2007. The main subjects discussed during this meeting were the status of international project dedicated to gamma spectroscopy research. The scientific research program includes investigations of giant dipole resonance, probe of hot nuclei induced in heavy reactions, Jacobi shape transitions, isospin mixing and nuclear multifragmentation. The mentioned programme needs Rand D development such as new scintillations materials as lanthanum chlorides and bromides as well as new photo detection sensors as avalanche photodiodes - such subjects are also subjects of discussion. Additionally results of computerized simulations of scintillation detectors properties by means of GEANT- 4 code are presented

  8. CMM Interim Check Design of Experiments (U)

    Energy Technology Data Exchange (ETDEWEB)

    Montano, Joshua Daniel [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-07-29

    Coordinate Measuring Machines (CMM) are widely used in industry, throughout the Nuclear Weapons Complex and at Los Alamos National Laboratory (LANL) to verify part conformance to design definition. Calibration cycles for CMMs at LANL are predominantly one year in length and include a weekly interim check to reduce risk. The CMM interim check makes use of Renishaw’s Machine Checking Gauge which is an off-the-shelf product simulates a large sphere within a CMM’s measurement volume and allows for error estimation. As verification on the interim check process a design of experiments investigation was proposed to test a couple of key factors (location and inspector). The results from the two-factor factorial experiment proved that location influenced results more than the inspector or interaction.

  9. Decision on performing interim analysis for comparative clinical trials.

    Science.gov (United States)

    Pak, Kyongsun; Jacobus, Susanna; Uno, Hajime

    2017-09-01

    In randomized-controlled trials, interim analyses are often planned for possible early trial termination to claim superiority or futility of a new therapy. While unblinding is necessary to conduct the formal interim analysis in blinded studies, blinded data also have information about the potential treatment difference between the groups. We developed a blinded data monitoring tool that enables investigators to predict whether they observe such an unblinded interim analysis results that supports early termination of the trial. Investigators may skip some of the planned interim analyses if an early termination is unlikely. We specifically focused on blinded, randomized-controlled studies to compare binary endpoints of a new treatment with a control. Assuming one interim analysis is planned for early termination for superiority or futility, we conducted extensive simulation studies to assess the impact of the implementation of our tool on the size, power, expected number of interim analyses, and bias in the treatment effect. The numerical study showed the proposed monitoring tool does not affect size or power, but dramatically reduces the expected number of interim analyses when the effect of the treatment difference is small. The tool serves as a useful reference when interpreting the summary of the blinded data throughout the course of the trial, without losing integrity of the study. This tool could potentially save the study resources and budget by avoiding unnecessary interim analyses.

  10. Interim report and accounts 1993/94

    International Nuclear Information System (INIS)

    1993-01-01

    An interim set of accounts and reports is presented here for 1993/1994 for the health science company Amersham International. The company's research programs focus on developments in life science research, nuclear medicine and industrial quality and safety assurance, with particular expertise in the application of radioactivity to labelling and detection at the molecular level. This report which covers the half-year to 30 September 1993 shows promising financial results, with turnover, operating profits and earnings per share all having risen. All life science markets report growth although difficult trading conditions are being reported in Europe. Two products in the Healthcare business have achieved progress, a pain palliation agent for bone metastases has been launched in the United States, and European approval has been gained for a new technetium based heart imaging agent. Further growth is expected for the company. (UK)

  11. 340 waste handling facility interim safety basis

    Energy Technology Data Exchange (ETDEWEB)

    VAIL, T.S.

    1999-04-01

    This document presents an interim safety basis for the 340 Waste Handling Facility classifying the 340 Facility as a Hazard Category 3 facility. The hazard analysis quantifies the operating safety envelop for this facility and demonstrates that the facility can be operated without a significant threat to onsite or offsite people.

  12. 340 waste handling facility interim safety basis

    International Nuclear Information System (INIS)

    VAIL, T.S.

    1999-01-01

    This document presents an interim safety basis for the 340 Waste Handling Facility classifying the 340 Facility as a Hazard Category 3 facility. The hazard analysis quantifies the operating safety envelop for this facility and demonstrates that the facility can be operated without a significant threat to onsite or offsite people

  13. Resource Use and Real-World Outcomes for Ranibizumab Treat and Extend for Neovascular Age-Related Macular Degeneration in the UK: Interim Results from TERRA.

    Science.gov (United States)

    Yang, Yit; Downey, Louise; Mehta, Hemal; Mushtaq, Bushra; Narendran, Niro; Patel, Nishal; Patel, Praveen J; Ayan, Filis; Gibson, Kara; Igwe, Franklin; Jeffery, Pete

    2017-06-01

    Ranibizumab is an inhibitor of vascular endothelial growth factor-A (anti-VEGF) approved for the treatment of neovascular age-related macular degeneration (nAMD). The treat and extend (T&E) regimen can potentially reduce the burden of clinic visits compared with a pro re nata (PRN) regimen. Retrospective, interim analyses of clinical effectiveness, treatment and resource use patterns were conducted using real-world data in England and Wales from the TERRA study. Two cohorts, those switching from a PRN to a T&E regimen ('prior PRN') and those initiating ranibizumab on the T&E regimen as their first anti-VEGF therapy ('anti-VEGF-naïve') were enrolled in TERRA. Retrospective clinical assessments were gathered from medical records, while resource use patterns were collected via an operating cost questionnaire completed by each study site. At the interim analysis cut-off date (15 November 2016), 11 sites had enrolled 145 patients (prior PRN: n = 110; anti-VEGF-naïve: n = 35). Mean change from baseline (date of first injection) in visual acuity and central subfield retinal thickness to 12 months was +7.6 Early Treatment Diabetic Retinopathy Study letters [95% confidence interval (CI) 2.8, 12.4; p = 0.003; n = 27] and -67.7 μm (95% CI -106.5, -28.9; p = 0.001, n = 29), respectively, in the anti-VEGF-naïve cohort. Most T&E clinics were run as one-stop services (same-day monitoring and injection), whereas 4/10 PRN clinics were run as two-stop services (monitoring and injection on different days). In general, one-stop clinics used less staff resources and were likely to be shorter in duration for healthcare providers than the cumulative time spent for two-stop clinics. This is the first real-world observational study conducted in England and Wales demonstrating the effectiveness of the ranibizumab T&E regimen in anti-VEGF-naïve patients. T&E is compatible with one-stop clinic services, which these real-world data suggest to be less resource intensive than

  14. Presentations

    International Nuclear Information System (INIS)

    2007-01-01

    The presented materials consist of presentations of international workshop which held in Warsaw from 4 to 5 October 2007. Main subject of the meeting was progress in manufacturing as well as research program development for neutron detector which is planned to be placed at GANIL laboratory and will be used in nuclear spectroscopy research

  15. CMM Interim Check (U)

    Energy Technology Data Exchange (ETDEWEB)

    Montano, Joshua Daniel [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-03-23

    Coordinate Measuring Machines (CMM) are widely used in industry, throughout the Nuclear Weapons Complex and at Los Alamos National Laboratory (LANL) to verify part conformance to design definition. Calibration cycles for CMMs at LANL are predominantly one year in length. Unfortunately, several nonconformance reports have been generated to document the discovery of a certified machine found out of tolerance during a calibration closeout. In an effort to reduce risk to product quality two solutions were proposed – shorten the calibration cycle which could be costly, or perform an interim check to monitor the machine’s performance between cycles. The CMM interim check discussed makes use of Renishaw’s Machine Checking Gauge. This off-the-shelf product simulates a large sphere within a CMM’s measurement volume and allows for error estimation. Data was gathered, analyzed, and simulated from seven machines in seventeen different configurations to create statistical process control run charts for on-the-floor monitoring.

  16. The Nord interim store

    International Nuclear Information System (INIS)

    Leushacke, D.F.; Rittscher, D.

    1996-01-01

    In line with the decision taken in 1990 to shut down and decommission the Greifswald and Rheinsberg Nuclear Power Stations, the waste management concept of the Energiewerke Nord is based on direct and complete decommissioning of the six shut down reactor units within the next fifteen years. One key element of this concept is the construction and use of the Zwischenlager Nord (Nord Interim Store, ZLN) for holding the existing nuclear fuels and for interim and decay storage of the radioactive materials arising in decommissioning and demolition. The owner and operator of the store is Energiewerke Nord GmbH. The interim store has the functions of a processing and Energiewerke Nord GmbH. The interim store has the functions of a processing and treatment station and buffer store for the flows of residues arising. As a radioactive waste management station, it accommodates nuclear fuels, radioactive waste or residues which are not treated any further. It is used as a buffer store to allow the materials accumulating in disassembly to be stored temporarily before or after treatment in order to ensure continuous loading of the treatment plants. When operated as a processing station, the ZLN is able to handle nearly all types of radioactive waste and residues arising, except for nuclear fuels. These installations allow the treatment of radioactive residues to be separated from the demolition work both physically and in time. The possibilities of interium storage and buffer storage of untreated waste and waste packages make for high flexibility in logistics and waste management strategy. (orig.) [de

  17. Presentation

    Directory of Open Access Journals (Sweden)

    Eduardo Vicente

    2013-06-01

    effectivities more than a number of fixed essential characteristics. Luiz Artur Ferrareto (UFRGS, undertaking a theoretical proposal for categorizing radio content in four different levels of planning (segment, form, programming and content itself tries to “compare and contrast the practices of Brazilian commercial broadcasting companies to those used on the radio in the United States, a reference market for our national entrepreneurs”. Madalena Oliveira (University of Minho focuses on the current stage of communication researches in Portugal reflecting on the challenges for studying a culture based on listening in times of looking. Marko Ala-Fossi, (University of Tampere beginning with the statement that “radio evolution greatly depends not only on the cultural context of a country but also on the whole social, political, economic development of societies” gives us a projection on radio development around the world for the next decades. Closing the dossier, Rafael Duarte Oliveira Venancio (UFU assuming radio as language by definition and not as a device understands it as a section and an operating model in such language as it intersects the world. Another six articles, not enrolled in the dossier, round the edition off. Fernando de Tacca debates the category of “photocine” recurring to three recent Spanish productions. Gustavo Souza investigates the possibility of identifying a point of view in documentary movies while establishing a debate that joins the materialities of image and sound with the subjectivity resulting from interpretation. Vinicius Bandeira develops on the special duplicity present in the movies between what is and what is not subsumed by the camera. Neide Jallageas proposes the study of visual communication design from the first modelings, attempting especially to the radical propositions from the early XXth century avant-garde movement. Gilson Schwartz debates on the impact from the distribution of videogames as hegemonic cultural practice in

  18. Nondestructive evaluation of creep-fatigue damage: an interim report

    International Nuclear Information System (INIS)

    Nickell, R.E.

    1977-02-01

    In view of the uncertainties involved in designing against creep-fatigue failure and the consequences of such failures in Class 1 nuclear components that operate at elevated temperature, the possibility of intermittent or even continuous non-destructive examination of these components has been considered. In this interim report some preliminary results on magnetic force and ultrasonic evaluation of creep-fatigue damage in an LMFBR steam generator material are presented. These results indicate that the non-destructive evaluation of pure creep damage will be extremely difficult. A set of biaxial creep-fatigue tests that are designed to discriminate between various failure theories is also described

  19. Immediate provisionalization in the esthetic zone: 1-year interim results from a prospective single-cohort multicenter study evaluating 3.0-mm-diameter tapered implants.

    Science.gov (United States)

    Kolinski, Martin; Hess, Pablo; Leziy, Sonia; Friberg, Bertil; Bellucci, Gionata; Trisciuoglio, Davide; Wagner, Wilfried; Moergel, Maximilian; Pozzi, Alessandro; Wiltfang, Jörg; Behrens, Eleonore; Zechner, Werner; Vasak, Christoph; Weigl, Paul

    2018-02-03

    The aim of this interim analysis of a 5-year prospective multicenter study is to evaluate clinical and radiological performance of immediately provisionalized 3.0-mm-diameter tapered implants. Patients needing implant rehabilitation of maxillary lateral incisors or mandibular lateral and central incisors were treated with 3.0-mm-diameter implants placed in extraction or healed sites and immediately provisionalized. Clinical and radiographic examinations were performed at implant insertion, 6 months thereafter, and are ongoing. Marginal bone levels and changes, complications, the papilla, plaque, and bleeding indices, and the pink esthetic score (PES) were evaluated at each follow-up visit. Of 112 enrolled patients, 77 patients (91 implants) met the inclusion criteria. Seventy-one patients with 82 implants completed the 1-year follow-up. Three implants failed yielding a CSR of 96.7%. All failures occurred within the first 3 months after implant insertion. Marginal bone level changes from insertion to 6 months was - 0.57 ± 1.30 mm (n = 75) and from insertion to 12 months - 0.25 ± 1.38 mm (n = 72). Fifteen non-serious complications were recorded. Papilla index score and PES improved at the 1-year follow-up. Plaque formation and bleeding-on-probing showed no statistically significant differences between the 6-month and the 1-year visit. This 1-year analysis demonstrated high survival, stable bone levels, and healthy soft tissue with 3.0-mm-diameter implants. Narrow diameter implants are a safe and predictable treatment option in patients with limited bone volume and/or limited interdental space and eligible for immediate loading protocols.

  20. Interim storage study report

    Energy Technology Data Exchange (ETDEWEB)

    Rawlins, J.K.

    1998-02-01

    High-level radioactive waste (HLW) stored at the Idaho Chemical Processing Plant (ICPP) in the form of calcine and liquid and liquid sodium-bearing waste (SBW) will be processed to provide a stable waste form and prepare the waste to be transported to a permanent repository. Because a permanent repository will not be available when the waste is processed, the waste must be stored at ICPP in an Interim Storage Facility (ISF). This report documents consideration of an ISF for each of the waste processing options under consideration.

  1. Interim storage report

    International Nuclear Information System (INIS)

    Rawlins, J.K.

    1998-02-01

    High-level radioactive waste (HLW) stored at the Idaho Chemical Processing Plant (ICPP) in the form of calcine and liquid and liquid sodium-bearing waste (SBW) will be processed to provide a stable waste form and prepare the waste to be transported to a permanent repository. Because a permanent repository will not be available when the waste is processed, the waste must be stored at ICPP in an Interim Storage Facility (ISF). This report documents consideration of an ISF for each of the waste processing options under consideration

  2. Control of the woolly apple aphid (Erisoma lanigerum Hausm.) by releasing earwigs (Forficula auricularia L.) and support oil applications - an interim report of first year results

    OpenAIRE

    Toups, I.; Zimmer, J.; Trautmann, M.; Fieger-Metag, N.; Buchleither, S.; Bathon, H.

    2008-01-01

    Abstract The woolly apple aphid (Erisoma lanigerum Hausm.) has been recognised for some years as a serious pest in organic fruit growing where they may cause severe economic damage due to a lack of control strategies. Based on preliminary results a new project has been started in 2007 testing combinations of releasing earwigs and oil applications in order to develop an on-farm control strategy. In this paper we present preliminary results of the first year of the project´s field trials. Th...

  3. Interim Report by Asia International Grid Connection Study Group

    Science.gov (United States)

    Omatsu, Ryo

    2018-01-01

    The Asia International Grid Connection Study Group Interim Report examines the feasibility of developing an international grid connection in Japan. The Group has investigated different cases of grid connections in Europe and conducted research on electricity markets in Northeast Asia, and identifies the barriers and challenges for developing an international grid network including Japan. This presentation introduces basic contents of the interim report by the Study Group.

  4. Compliance & operating rules : results of a focus group

    Science.gov (United States)

    1997-05-01

    This interim report presents the results ofa focus group session onrailroad : operating rules and compliance. In addition, it summarizes information gathered from : structured interviews with various railroad managers, government officials, and other...

  5. Interim storage of solidified fission products from fuel element reprocessing with utilization of obtaining post-decay heat

    International Nuclear Information System (INIS)

    Kelm, W.

    1983-01-01

    It is noted that the out-lined interim store for HRW with industrial utilization of decay heat (production of saturated steam and hydrogen) does include a certain risk potential like any technical plant but that it does not represent a danger to the population living nearby. All internal and external impacts on the store result in safely triggering natural convection cooling. A further emergency cooling system is provided by the water irrigation facility so that obtaining after-heat can be safely removed under all circumstances. Therefore, there are no safety-technology arguments against any realization of the concept presented for interim storage of solidified high-level radio-active wastes. An interim store of this type may be built and operated even in densely populated regions and urban agglomerations. (orig./HP) [de

  6. Spent fuel interim storage

    International Nuclear Information System (INIS)

    Bilegan, Iosif C.

    2003-01-01

    The official inauguration of the spent fuel interim storage took place on Monday July 28, 2003 at Cernavoda NNP. The inaugural event was attended by local and central public authority representatives, a Canadian Government delegation as well as newsmen from local and central mass media and numerous specialists from Cernavoda NPP compound. Mr Andrei Grigorescu, State Secretary with the Economy and Commerce Ministry, underlined in his talk the importance of this objective for the continuous development of nuclear power in Romania as well as for Romania's complying with the EU practice in this field. Also the excellent collaboration between the Canadian contractor AECL and the Romanian partners Nuclear Montaj, CITON, UTI, General Concret in the accomplishment of this unit at the planned terms and costs. On behalf of Canadian delegation, spoke Minister Don Boudria. He underlined the importance which the Canadian Government affords to the cooperation with Romania aiming at specific objectives in the field of nuclear power such as the Cernavoda NPP Unit 2 and spent fuel interim storage. After traditional cutting of the inaugural ribbon by the two Ministers the festivities continued on the Cernavoda NPP Compound with undersigning the documents regarding the project completion and a press conference

  7. The information content of SFAS No 131 interim segment reporting

    OpenAIRE

    Joong-Seok Cho

    2010-01-01

    This study empirically investigates the effect of implementation of SFAS No.131 on companies' information environments by assessing the effect of interim period financial reports. Especially, using Beaver's information content measures, it investigates the market's reaction to interim period financial reporting under SFAS No.131. The empirical results of the information content test show that the adoption of SFAS No.131 does not affect the market's reaction. For the volume reaction test, no d...

  8. FedEx Gasoline Hybrid Electric Delivery Truck Evaluation: 6-Month Interim Report

    Energy Technology Data Exchange (ETDEWEB)

    Barnitt, R.

    2010-05-01

    This interim report presents partial (six months) results for a technology evaluation of gasoline hybrid electric parcel delivery trucks operated by FedEx in and around Los Angeles, CA. A 12 month in-use technology evaluation comparing in-use fuel economy and maintenance costs of GHEVs and comparative diesel parcel delivery trucks was started in April 2009. Comparison data was collected and analyzed for in-use fuel economy and fuel costs, maintenance costs, total operating costs, and vehicle uptime. In addition, this interim report presents results of parcel delivery drive cycle collection and analysis activities as well as emissions and fuel economy results of chassis dynamometer testing of a gHEV and a comparative diesel truck at the National Renewable Energy Laboratory's (NREL) ReFUEL laboratory. A final report will be issued when 12 months of in-use data have been collected and analyzed.

  9. Immobilized high-level waste interim storage alternatives generation and analysis and decision report

    International Nuclear Information System (INIS)

    CALMUS, R.B.

    1999-01-01

    This report presents a study of alternative system architectures to provide onsite interim storage for the immobilized high-level waste produced by the Tank Waste Remediation System (TWRS) privatization vendor. It examines the contract and program changes that have occurred and evaluates their impacts on the baseline immobilized high-level waste (IHLW) interim storage strategy. In addition, this report documents the recommended initial interim storage architecture and implementation path forward

  10. Federal Interim Storage program

    International Nuclear Information System (INIS)

    Johnson, E.R.; McBride, J.A.

    1984-01-01

    The DOE has developed a program for providing Federal Interim Storage servies for spent nuclear fuel which complies with the requirements of the Nuclear Waste Policy Act of 1982. Although very little constructive activity in providing storage facilities can be undertaken by DOE until fuel has been certified by NRC as eligible for FIS, DOE planning and background information is such as to provide reasonable assurance that its obligations can be fulfilled when the required certifications have been issued. A fee structure providing fuel recovery of all costs associated with the FIS program, as required by the Act, has been developed. It provides for an equitable distribution of costs among users, based on the quantity of fuel requiring storage

  11. Report of the evaluation by the Ad Hoc Review Committee on advance science research. Result evaluation, interim evaluation, in-advance evaluation in fiscal year 2003

    International Nuclear Information System (INIS)

    2003-11-01

    The Research Evaluation Committee, which consisted of 13 members from outside of the Japan Atomic Energy Research Institute (JAERI), set up an Ad Hoc Review Committee on Advanced Science Research in accordance with the Fundamental Guideline for the Evaluation of Research and Development (R and D) at JAERI' and its subsidiary regulations in order to evaluate the accomplishments of the research completed in Fiscal Year 2002, the accomplishments of the research started in Fiscal Year 2001, and the adequacy of the programs of the research to be started in Fiscal Year 2004 at Advanced Science Research Center of JAERI. The Ad Hoc Review Committee consisted of nine specialists from outside of JAERI. The Ad Hoc Review Committee conducted its activities from May to July 2003. The evaluation was performed on the basis of the materials submitted in advance and of the oral presentations made at the Ad Hoc Review Committee meeting which was held on June 24, 2003, in line with the items, viewpoints, and criteria for the evaluation specified by the Research Evaluation Committee. The result of the evaluation by the Ad Hoc Review Committee was submitted to the Research Evaluation Committee, and was judged to be appropriate at its meeting held on August 4, 2003. This report describes the result of the evaluation by the Ad Hoc Review Committee on Advanced Science Research. (author)

  12. Report of the evaluation by the Ad Hoc Review Committee on Advance Science Research. Result evaluation, interim evaluation, in-advance evaluation in fiscal year 2002

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-11-01

    The Research Evaluation Committee, which consisted of 13 members from outside of the Japan Atomic Energy Research Institute (JAERI), set up an Ad Hoc Review Committee on Advanced Science Research in accordance with the Fundamental Guideline for the Evaluation of Research and Development (R and D) at JAERI' and its subsidiary regulations in order to evaluate the accomplishments of the research completed in Fiscal Year 2001, the accomplishments of the research started in Fiscal Year 2000, and the adequacy of the programs of the research to be started in Fiscal Year 2003 at Advanced Science Research Center of JAERI. The Ad Hoc Review Committee consisted of eight specialists from outside of JAERI. The Ad Hoc Review Committee conducted its activities from May to July 2002. The evaluation was performed on the basis of the materials submitted in advance and of the oral presentations made at the Ad Hoc Review Committee meeting which was held on June 4, 2002, in line with the items, viewpoints, and criteria for the evaluation specified by the Research Evaluation Committee. The result of the evaluation by the Ad Hoc Review Committee was submitted to the Research Evaluation Committee, and was judged to be appropriate at its meeting held on August 5, 2002. This report describes the result of the evaluation by the Ad Hoc Review Committee on Advanced Science Research. (author)

  13. Pathways to deep decarbonization - Interim 2014 Report

    International Nuclear Information System (INIS)

    2014-01-01

    The interim 2014 report by the Deep Decarbonization Pathways Project (DDPP), coordinated and published by IDDRI and the Sustainable Development Solutions Network (SDSN), presents preliminary findings of the pathways developed by the DDPP Country Research Teams with the objective of achieving emission reductions consistent with limiting global warming to less than 2 deg. C. The DDPP is a knowledge network comprising 15 Country Research Teams and several Partner Organizations who develop and share methods, assumptions, and findings related to deep decarbonization. Each DDPP Country Research Team has developed an illustrative road-map for the transition to a low-carbon economy, with the intent of taking into account national socio-economic conditions, development aspirations, infrastructure stocks, resource endowments, and other relevant factors. The interim 2014 report focuses on technically feasible pathways to deep decarbonization

  14. Safety of Long-term Interim Storage Facilities - Workshop Proceedings

    International Nuclear Information System (INIS)

    2014-01-01

    The objective of this workshop was to discuss and review current national activities, plans and regulatory approaches for the safety of long term interim storage facilities dedicated to spent nuclear fuel (SF), high level waste (HLW) and other radioactive materials with prolonged storage regimes. It was also intended to discuss results of experiments and to identify necessary R and D to confirm safety of fuel and cask during the long-term storage. Safety authorities and their Technical Support Organisation (TSO), Fuel Cycle Facilities (FCF) operating organisations and international organisations were invited to share information on their approaches, practices and current developments. The workshop was organised in an opening session, three technical sessions, and a conclusion session. The technical sessions were focused on: - National approaches for long term interim storage facilities; - Safety requirements, regulatory framework and implementation issues; - Technical issues and operational experience, needs for R and D. Each session consisted of a number of presentations followed by a panel discussion moderated by the session Chairs. A summary of each session and subsequent discussion that ensued are provided as well as a summary of the results of the workshop with the text of the papers given and presentations made

  15. Preventive maintenance study : interim report.

    Science.gov (United States)

    2017-09-01

    This interim report details the performance of 69 test sites treated with various preventive maintenance treatments. The maintenance treatments applied included crack sealing, full lane chip sealing, wheel path chip sealing, dig outs (mill and fill),...

  16. Analysis and presentation of experimental results with examples, problems and programs

    CERN Document Server

    Christodoulides, Costas

    2017-01-01

    This book is intended as a guide to the analysis and presentation of experimental results. It develops various techniques for the numerical processing of experimental data, using basic statistical methods and the theory of errors. After presenting basic theoretical concepts, the book describes the methods by which the results can be presented, both numerically and graphically. The book is divided into three parts, of roughly equal length, addressing the theory, the analysis of data, and the presentation of results. Examples are given and problems are solved using the Excel, Origin, Python and R software packages. In addition, programs in all four languages are made available to readers, allowing them to use them in analyzing and presenting the results of their own experiments. Subjects are treated at a level appropriate for undergraduate students in the natural sciences, but this book should also appeal to anyone whose work involves dealing with experimental results.

  17. An open label, single-arm, phase II multicenter study of the safety and efficacy of CG0070 oncolytic vector regimen in patients with BCG-unresponsive non-muscle-invasive bladder cancer: Interim results.

    Science.gov (United States)

    Packiam, Vignesh T; Lamm, Donald L; Barocas, Daniel A; Trainer, Andrew; Fand, Benjamin; Davis, Ronald L; Clark, William; Kroeger, Michael; Dumbadze, Igor; Chamie, Karim; Kader, A Karim; Curran, Dominic; Gutheil, John; Kuan, Arthur; Yeung, Alex W; Steinberg, Gary D

    2017-07-26

    CG0070 is a replication-competent oncolytic adenovirus that targets bladder tumor cells through their defective retinoblastoma pathway. Prior reports of intravesical CG0070 have shown promising activity in patients with high-grade non-muscle invasive bladder cancer (NMIBC) who previously did not respond to bacillus Calmette-Guérin (BCG). However, limited accrual has hindered analysis of efficacy, particularly for pathologic subsets. We evaluated interim results of a phase II trial for intravesical CG0070 in patients with BCG-unresponsive NMIBC who refused cystectomy. At interim analysis (April 2017), 45 patients with residual high-grade Ta, T1, or carcinoma-in-situ (CIS) ± Ta/T1 had evaluable 6-month follow-up in this phase II single-arm multicenter trial (NCT02365818). All patients received at least 2 prior courses of intravesical therapy for CIS, with at least 1 being a course of BCG. Patients had either failed BCG induction therapy within 6 months or had been successfully treated with BCG with subsequent recurrence. Complete response (CR) at 6 months was defined as absence of disease on cytology, cystoscopy, and random biopsies. Of 45 patients, there were 24 pure CIS, 8 CIS + Ta, 4 CIS + T1, 6 Ta, 3 T1. Overall 6-month CR (95% CI) was 47% (32%-62%). Considering 6-month CR for pathologic subsets, pure CIS was 58% (37%-78%), CIS ± Ta/T1 50% (33%-67%), and pure Ta/T1 33% (8%-70%). At 6 months, the single patient that progressed to muscle-invasive disease had Ta and T1 tumors at baseline. No patients with pure T1 had 6-month CR. Treatment-related adverse events (AEs) at 6 months were most commonly urinary bladder spasms (36%), hematuria (28%), dysuria (25%), and urgency (22%). Immunologic treatment-related AEs included flu-like symptoms (12%) and fatigue (6%). Grade III treatment-related AEs included dysuria (3%) and hypotension (1.5%). There were no Grade IV/V treatment-related AEs. This phase II study demonstrates that intravesical CG0070 yielded an overall 47

  18. Immediate rehabilitation of the edentulous jaws with full fixed prostheses supported by four implants: interim results of a single cohort prospective study.

    Science.gov (United States)

    Agliardi, Enrico; Panigatti, Stefano; Clericò, Matteo; Villa, Cristina; Malò, Paulo

    2010-05-01

    The purpose of this study was to prospectively evaluate the clinical and radiographic outcomes of immediately loaded full-arch fixed prostheses supported by a combination of axially and non-axially positioned implants in a large cohort of patients with completely edentulous jaws, up to 5 years of function. One hundred and seventy-three edentulous patients (80 males and 93 females) were enrolled according to specific selection criteria. Each patient received a full-arch fixed prosthesis supported by two distal tilted implants and two anterior axially placed implants. The provisional functional acrylic prosthesis was delivered the same day as surgery in all cases. All cases were finalized 4-6 months later. The patients were scheduled for follow-up at 6 and 12 months of function, and annually up to 5 years. At each follow-up plaque and bleeding score was assessed and radiographic evaluation of marginal bone level was performed. The overall follow-up range was 4-59 months. A total of 154 immediately loaded prostheses (61 in the maxilla and 93 in the mandible) were in function for at least 1 year and were considered for the analysis. Four axially placed implants failed in the maxilla and one tilted implant in the mandible, all within 6 months of loading. No further implant failure occurred to date. Implant survival at 1 year was 98.36% and 99.73% for the maxilla and the mandible, respectively. Marginal bone loss at 1 year averaged 0.9+/-0.7 mm in the maxilla (204 implants) and 1.2+/-0.9 mm in the mandible (292 implants). No difference was found in marginal bone loss between axial and tilted implants. Plaque and bleeding scores progressively improved from 6 to 12 months. Fracture of the acrylic prosthesis occurred in 14% of total cases. The present preliminary results from a relatively large sample size suggest that the present technique can be considered a viable treatment option for the immediate rehabilitation of both mandible and maxilla.

  19. Safety and efficacy of ipragliflozin in Japanese patients with type 2 diabetes in real-world clinical practice: interim results of the STELLA-LONG TERM post-marketing surveillance study.

    Science.gov (United States)

    Nakamura, Ichiro; Maegawa, Hiroshi; Tobe, Kazuyuki; Tabuchi, Hiromi; Uno, Satoshi

    2018-02-01

    Data regarding the efficacy and safety of sodium-glucose cotransporter 2 inhibitors in the real-world setting in Japan are limited. The STELLA-LONG TERM study is an ongoing 3-year post-marketing surveillance study of ipragliflozin in type 2 diabetes (T2D) patients. Here, we report the interim results (including 3-, 12-, and 24-month data). All Japanese patients with T2D who were first prescribed ipragliflozin between 17 July 2014 and 16 October 2015 at participating centers in Japan were registered in STELLA-LONG TERM. At 3, 12, and 24 months, the safety analysis set comprised 11,053, 5475, and 138 patients, respectively; the efficacy analysis set comprised 8757 patients. Ipragliflozin treatment resulted in statistically significant improvements versus baseline in hemoglobin A1c, fasting plasma glucose concentration, body weight, blood pressure, heart rate, and serum concentrations of low-density lipoprotein cholesterol and triglycerides. The adverse drug reaction incidence rate was 10.71%, the most common reactions being renal and urinary disorders (5.06%), infections and infestations (1.24%), and skin and subcutaneous tissue disorders (1.14%). Ipragliflozin was well tolerated and effective in Japanese patients with T2D; no new safety issues were identified.

  20. Continuous solvent extraction feed adjustment for HTGR fuel reprocessing. Interim development report

    International Nuclear Information System (INIS)

    Olguin, L.J.

    1978-06-01

    The two-cycle Acid-Thorex solvent extraction process requires that the feed stream to each thorium cycle be processed to reduce its nitric acid concentration (feed adjustment). This interim development report presents the results of bench-scale and pilot-plant-scale feed adjustment experiments using a continuous mode of operation. An examination of formic acid denitration and fluoride ion volatilization is also included

  1. Gaz de France interim financial report 2007

    International Nuclear Information System (INIS)

    2007-01-01

    This financial report contains the unaudited condensed financial statements of Gaz de France Group for the first half ended June 30, 2007, which were reviewed by the audit committee on August 27, 2007 and by the board of directors at its meeting on August 28, 2007. It includes forward-looking statements concerning the objectives, strategies, financial position, future operating results and the operations of Gaz de France Group. These statements reflect the Group's current perception of its activities and the markets in which it operates, as well as various estimates and assumptions considered to be reasonable. Content: interim management report (highlights of the first half of 2007, revenues and results for the period, financial structure, data on outstanding stock, outlook); interim consolidated financial statements (consolidated statements of income, consolidated balance sheets, consolidated statements of cash flows, recognized income and expenses, statements of changes in shareholders' equity, note to the consolidated financial statements); statement by the person responsible for the interim financial report; statutory auditors' report. (J.S.)

  2. INTERIM RESULTS FROM A STUDY OF THE IMPACTS OF TIN(II) BASED MERCURY TREATMENT IN A SMALL STREAM ECOSYSTEM: TIMS BRANCH, SAVANNAH RIVER SITE

    Energy Technology Data Exchange (ETDEWEB)

    Looney, B.; Bryan, L.; Mathews, T.

    2012-03-30

    source control measures have resulted in rapid responses in lake or reservoir fisheries (Joslin 1994, Turner and Southworth 1999; Orihel et al., 2007), but examples of similar responses in Hg-contaminated stream ecosystems are less common. Recent work suggests that stream systems may actually be more susceptible to mercury bioaccumulation than lakes, highlighting the need to better understand the ecological drivers of mercury bioaccumulation in stream-dwelling fish (Chasar et al. 2009, Ward et al. 2010). In the present study we examine the response of fish to remedial actions in Tims Branch, a point-source contaminated stream on the Department of Energy's (DOE) Savannah River Site in Aiken, South Carolina. This second order stream received inorganic mercury inputs at its headwaters from the 1950s-2000s which contaminated the water, sediments, and biota downstream. In 2007, an innovative mercury removal system using tin (II) chloride (stannous chloride, SnCl{sub 2}) was implemented at a pre-existing air stripper. Tin(II) reduces dissolved Hg (II) to Hg (0), which is removed by the air stripper. During this process, tin(II) is oxidized to tin (IV) which is expected to precipitate as colloidal tin(IV) oxides and hydroxides, particulate materials with relatively low toxicity (Hallas and Cooney, 1981, EPA 2002, ATSDR, 2005). The objectives of the present research are to provide an initial assessment of the net impacts of the tin(II) based mercury treatment on key biota and to document the distribution and fate of inorganic tin in this small stream ecosystem after the first several years of operating a full scale system. To support these objectives, we collected fish, sediment, water, invertebrates, and biofilm samples from Tims Branch to quantify the general behavior and accumulation patterns for mercury and tin in the ecosystem and to determine if the treatment process has resulted in: (1) a measurable beneficial impact on (i.e., decrease of) mercury concentration in

  3. Experimental summary talk. A summary of the experimental results presented at Moriond QCD 2001

    Energy Technology Data Exchange (ETDEWEB)

    Pietrzyk, B

    2001-06-01

    A summary of the experimental results presented at Moriond QCD 2001 are given. The author reviews results concerning the expected mass of the Higgs boson, the discovery of new particles, heavy-ion collision physics, structure functions, diffractive J/{psi} production, WW physics, heavy flavours and the first results given by BaBar and Belle installations.

  4. Experimental summary talk. A summary of the experimental results presented at Moriond QCD 2001

    International Nuclear Information System (INIS)

    Pietrzyk, B.

    2001-06-01

    A summary of the experimental results presented at Moriond QCD 2001 are given. The author reviews results concerning the expected mass of the Higgs boson, the discovery of new particles, heavy-ion collision physics, structure functions, diffractive J/Ψ production, WW physics, heavy flavours and the first results given by BaBar and Belle installations

  5. Specific provisions applicable to the production, inspection, treatment, packaging and interim storage of low and medium level bituminized wastes resulting from the reprocessing of fuels irradiated in pressurized water reactors

    International Nuclear Information System (INIS)

    1984-04-01

    The Fundamental Safety Rules applicable to certain types of nuclear installation are intended to clarify the conditions of which observance, for the type of installation concerned and for the subject that they deal with, is considered as equivalent to compliance with regulatory French technical practice. These Rules should facilitate safety analysises and the clear understanding between persons interested in matters related to nuclear safety. They in no way reduce the operator's liability and pose no obstacle to statutory provisions in force. For any installation to which a Fundamental Safety Rule applies according to the foregoing paragraph, the operator may be relieved from application of the Rule if he shows proof that the safety objectives set by the Rule are attained by other means that he proposes within the framework of statutory procedures. Furthermore, the Central Service for the Safety of Nuclear Installations reserves the right at all times to alter any Fundamental Safety Rule, as required, should it deem this necessary, while specifying the applicability conditions. This rule sets forth the specific provisions applicable to the production, inspection, treatment, packaging and interim storage of the wastes, resulting from the reprocessing of fuels irradiated in a PWR and coated in bitumen

  6. Particular provisions applicable to the production, inspection, treatment, packaging and interim storage of wastes immobilized in cement, resulting from the reprocessing of fuels irradiated in pressurized light water reactors

    International Nuclear Information System (INIS)

    1985-02-01

    The Fundamental Safety Rules applicable to certain types of nuclear installation are intended to clarify the conditions of which observance, for the type of installation concerned and for the subject that they deal with, is considered as equivalent to compliance with regulatory French technical practice. These Rules should facilitate safety analysises and the clear understanding between persons interested in matters related to nuclear safety. They in no way reduce the operator's liability and pose no obstacle to statutory provisions in force. For any installation to which a Fundamental Safety Rule applies according to the foregoing paragraph, the operator may be relieved from application of the Rule if he shows proof that the safety objectives set by the Rule are attained by other means that he proposes within the framework of statutory procedures. Furthermore, the Central Service for the Safety of Nuclear Installations reserves the right at all times to alter any Fundamental Safety Rule, as required, should it deem this necessary, while specifying the applicability conditions. This rule is intended to stipulate the specific provisions applicable to the production, inspection, treatment, packaging and interim storage of the wastes, resulting from the reprocessing of fuels irradiated in a PWR and immobilized in cement

  7. The FODA-TDMA satellite access scheme - Presentation, study of the system, and results

    Science.gov (United States)

    Celandroni, Nedo; Ferro, Erina

    1991-12-01

    A description is given of FODA-TDMA, a satellite access scheme designed for mixed traffic. The study of the system is presented and the choice of some parameters is justified. A simplified analytic solution is found, describing the steady-state behavior of the system. Some results of the simulation tests for an already existing hardware environment are also presented for the channel speeds of 2 and 8 Mb/s, considering both the stationary and the transient cases. The results of the experimentation at 2 Mb/s on the satellite Eutelsat-F2 are also presented and compared with the results of the simulation.

  8. A selective laser sintering prototype guide used to fabricate immediate interim fixed complete arch prostheses in flapless dental implant surgery: Technique description and clinical results.

    Science.gov (United States)

    Di Giacomo, Giovanni de A P; Cury, Patricia R; da Silva, Airton M; da Silva, Jorge V L; Ajzen, Sergio A

    2016-12-01

    Extensive occlusal adjustments and misfit of the prosthesis to prosthetic components are frequent problems related to fixed interim prosthesis fabrication with immediate dental implant loading. The purpose of this clinical trial was to evaluate a prosthetic guide made with a rapid prototype model based on virtual surgical planning. This prosthetic guide was used to fabricate fixed interim prostheses that would allow immediate implant loading after computer-guided implant installation. Nine interim prostheses were made for 9 participants with complete maxillary or mandibular edentulism. The virtual prosthetic guide was planned using computer-assisted design (CAD) software and was fabricated with rapid prototyping equipment (selective laser sintering). The prosthetic guide had 3 portions: the occlusal portion, which had occlusal registration; the connection portion, which had the information of the position and angulation of the abutment/implant projection; and the mucosa portion, which had the registration of the alveolar mucosa architecture. The prosthetic guide was used by a dental technician to fabricate prostheses. A single trained examiner evaluated the passive fit of the interim prostheses, the average time required for installing the interim prosthesis and for occlusal adjustments, the satisfaction of the patient with the prosthesis; and the screws, torque, occlusion, and prosthesis status. Passive fit was achieved between the prosthetic components and prostheses in 7 participants. The average time required for installing the fixed interim prostheses was 64.44 minutes. All participants reported being more pleased with the fixed interim prosthesis than with the prosthesis worn before implant placement. Prosthesis fractures were observed in 3 participants (2 in the maxilla and 1 in the mandible); all fractures occurred 3 months or more after delivery. No further complication was observed during 6 months of follow-up. The prosthetic guide enabled fabrication of

  9. Searches for New Physics: Les Houches Recommendations for the Presentation of LHC Results

    International Nuclear Information System (INIS)

    Kraml, S.; Allanach, B.C.; Mangano, M.; Prosper, H.B.; Sekmen, S.; Balazs, C.; Barr, A.; Bechtle, P.; Belanger, G.; Belyaev, A.; Kenslama, K.; Campanelli, M.; Cranmer, K.; De Roeck, A.; Dolan, M.J.; Ellis, J.R.; Felcini, M.; Fuks, B.; Guadagnoli, D.; Gunion, J.F.; Heinemeyer, S.; Hewett, J.; Ismail, A.; Kadastik, M.; Kraemer, M.; Lykken, J.; Mahmoudi, F.; Martin, S.P.; Rizzo, T.; Robens, T.; Tytgat, M.; Weiler, A.

    2012-01-01

    We present a set of recommendations for the presentation of LHC results on searches for new physics, which are aimed at providing a more efficient flow of scientific information between the experimental collaborations and the rest of the high energy physics community, and at facilitating the interpretation of the results in a wide class of models. Implementing these recommendations would aid the full exploitation of the physics potential of the LHC. (authors)

  10. Searches for new physics: Les Houches recommendations for the presentation of LHC results

    International Nuclear Information System (INIS)

    Kraml, S.; Allanach, B.C.; Mangano, M.; Roeck, A. de; Prosper, H.B.; Sekmen, S.; Balazs, C.; Barr, A.; Bechtle, P.; Belanger, G.; Belyaev, A.; Benslama, K.; Campanelli, M.; Cranmer, K.; Dolan, M.J.; Eifert, T.; Hewett, J.; Ismail, A.; Rizzo, T.; Ellis, J.R.; Felcini, M.; Heinemeyer, S.; Fuks, B.; Guadagnoli, D.; Gunion, J.F.; Kadastik, M.; Kraemer, M.; Lykken, J.; Mahmoudi, F.; Martin, S.P.; Robens, T.; Tytgat, M.; Weiler, A.

    2012-01-01

    We present a set of recommendations for the presentation of LHC results on searches for new physics, which are aimed at providing a more efficient flow of scientific information between the experimental collaborations and the rest of the high energy physics community, and at facilitating the interpretation of the results in a wide class of models. Implementing these recommendations would aid the full exploitation of the physics potential of the LHC. (orig.)

  11. Searches for new physics: Les Houches recommendations for the presentation of LHC results

    Energy Technology Data Exchange (ETDEWEB)

    Kraml, S.; /LPSC, Grenoble; Allanach, B.C.; /Cambridge U., DAMTP; Mangano, M.; /CERN; Prosper, H.B.; /Florida State U.; Sekmen, S.; /CERN /Florida State U.; Balazs, C.; /Monash U.; Barr, A.; /Oxford U.; Bechtle, P.; /Bonn U.; Belanger, G.; /Annecy, LAPTH; Belyaev, A.; /Rutherford /Southampton U.; Benslama, K.; /Regina U.; Campanelli, M.; /University Coll. London; Cranmer, K.; /New York U., CCPP; De Roeck, A.; /CERN; Dolan, M.J.; /Durham U., IPPP; Eifert, T.; /SLAC; Ellis, J.R.; /King' s Coll. London /CERN; Felcini, M.; /Cantabria U., Santander; Fuks, B.; /Strasbourg, IPHC /Strasbourg, IReS; Guadagnoli, D.; /Orsay, LPT /Annecy, LAPTH; Gunion, J.F.; /UC, Davis /Cantabria U., Santander /SLAC /NICPB, Tallinn /Aachen, Tech. Hochsch. /Fermilab /Clermont-Ferrand U. /CERN /Clermont-Ferrand U. /Northern Illinois U. /Santa Barbara, KITP /SLAC /Dresden, Tech. U. /Gent U. /DESY

    2012-04-17

    We present a set of recommendations for the presentation of LHC results on searches for new physics, which are aimed at providing a more efficient flow of scientific information between the experimental collaborations and the rest of the high energy physics community, and at facilitating the interpretation of the results in a wide class of models. Implementing these recommendations would aid the full exploitation of the physics potential of the LHC.

  12. Tables or bar graphs? Presenting test results in electronic medical records.

    Science.gov (United States)

    Brewer, Noel T; Gilkey, Melissa B; Lillie, Sarah E; Hesse, Bradford W; Sheridan, Stacey L

    2012-01-01

    Electronic personal health records offer a promising way to communicate medical test results to patients. We compared the usability of tables and horizontal bar graphs for presenting medical test results electronically. We conducted experiments with a convenience sample of 106 community-dwelling adults. In the first experiment, participants viewed either table or bar graph formats (between subjects) that presented medical test results with normal and abnormal findings. In a second experiment, participants viewed table and bar graph formats (within subjects) that presented test results with normal, borderline, and abnormal findings. Participants required less viewing time when using bar graphs rather than tables. This overall difference was due to superior performance of bar graphs in vignettes with many test results. Bar graphs and tables performed equally well with regard to recall accuracy and understanding. In terms of ease of use, participants did not prefer bar graphs to tables when they viewed only one format. When participants viewed both formats, those with experience with bar graphs preferred bar graphs, and those with experience with tables found bar graphs equally easy to use. Preference for bar graphs was strongest when viewing tests with borderline results. Compared to horizontal bar graphs, tables required more time and experience to achieve the same results, suggesting that tables can be a more burdensome format to use. The current practice of presenting medical test results in a tabular format merits reconsideration.

  13. Initial experience with a group presentation of study results to research participants

    Directory of Open Access Journals (Sweden)

    Bent Stephen

    2008-03-01

    Full Text Available Abstract Background Despite ethical imperatives, informing research participants about the results of the studies in which they take part is not often performed. This is due, in part, to the costs and burdens of communicating with each participant after publication of the results. Methods Following the closeout and publication of a randomized clinical trial of saw palmetto for treatment of symptoms of benign prostatic hyperplasia, patients were invited back to the research center to participate in a group presentation of the study results. Results Approximately 10% of participants attended one of two presentation sessions. Reaction to the experience of the group presentation was very positive among the attendees. Conclusion A group presentation to research participants is an efficient method of communicating study results to those who desire to be informed and was highly valued by those who attended. Prospectively planning for such presentations and greater scheduling flexibility may result in higher attendance rates. Trial Registration Number Clinicaltrials.gov #NCT00037154

  14. Methods Data Qualification Interim Report

    Energy Technology Data Exchange (ETDEWEB)

    R. Sam Alessi; Tami Grimmett; Leng Vang; Dave McGrath

    2010-09-01

    The overall goal of the Next Generation Nuclear Plant (NGNP) Data Management and Analysis System (NDMAS) is to maintain data provenance for all NGNP data including the Methods component of NGNP data. Multiple means are available to access data stored in NDMAS. A web portal environment allows users to access data, view the results of qualification tests and view graphs and charts of various attributes of the data. NDMAS also has methods for the management of the data output from VHTR simulation models and data generated from experiments designed to verify and validate the simulation codes. These simulation models represent the outcome of mathematical representation of VHTR components and systems. The methods data management approaches described herein will handle data that arise from experiment, simulation, and external sources for the main purpose of facilitating parameter estimation and model verification and validation (V&V). A model integration environment entitled ModelCenter is used to automate the storing of data from simulation model runs to the NDMAS repository. This approach does not adversely change the why computational scientists conduct their work. The method is to be used mainly to store the results of model runs that need to be preserved for auditing purposes or for display to the NDMAS web portal. This interim report demonstrates the currently development of NDMAS for Methods data and discusses data and its qualification that is currently part of NDMAS.

  15. International validation study for interim PET in ABVD-treated, advanced-stage hodgkin lymphoma

    DEFF Research Database (Denmark)

    Biggi, Alberto; Gallamini, Andrea; Chauvie, Stephane

    2013-01-01

    At present, there are no standard criteria that have been validated for interim PET reporting in lymphoma. In 2009, an international workshop attended by hematologists and nuclear medicine experts in Deauville, France, proposed to develop simple and reproducible rules for interim PET reporting...

  16. PROJECT W-551 INTERIM PRETREATMENT SYSTEM TECHNOLOGY SELECTION SUMMARY DECISION REPORT AND RECOMMENDATION

    Energy Technology Data Exchange (ETDEWEB)

    CONRAD EA

    2008-08-12

    This report provides the conclusions of the tank farm interim pretreatment technology decision process. It documents the methodology, data, and results of the selection of cross-flow filtration and ion exchange technologies for implementation in project W-551, Interim Pretreatment System. This selection resulted from the evaluation of specific scope criteria using quantitative and qualitative analyses, group workshops, and technical expert personnel.

  17. PROJECT W-551 INTERIM PRETREATMENT SYSTEM TECHNOLOGY SELECTION SUMMARY DECISION REPORT AND RECOMMENDATION

    International Nuclear Information System (INIS)

    CONRAD EA

    2008-01-01

    This report provides the conclusions of the tank farm interim pretreatment technology decision process. It documents the methodology, data, and results of the selection of cross-flow filtration and ion exchange technologies for implementation in project W-551, Interim Pretreatment System. This selection resulted from the evaluation of specific scope criteria using quantitative and qualitative analyses, group workshops, and technical expert personnel

  18. Interim Hanford Waste Management Plan

    International Nuclear Information System (INIS)

    1985-09-01

    The September 1985 Interim Hanford Waste Management Plan (HWMP) is the third revision of this document. In the future, the HWMP will be updated on an annual basis or as major changes in disposal planning at Hanford Site require. The most significant changes in the program since the last release of this document in December 1984 include: (1) Based on studies done in support of the Hanford Defense Waste Environmental Impact Statement (HDW-EIS), the size of the protective barriers covering contaminated soil sites, solid waste burial sites, and single-shell tanks has been increased to provide a barrier that extends 30 m beyond the waste zone. (2) As a result of extensive laboratory development and plant testing, removal of transuranic (TRU) elements from PUREX cladding removal waste (CRW) has been initiated in PUREX. (3) The level of capital support in years beyond those for which specific budget projections have been prepared (i.e., fiscal year 1992 and later) has been increased to maintain Hanford Site capability to support potential future missions, such as the extension of N Reactor/PUREX operations. The costs for disposal of Hanford Site defense wastes are identified in four major areas in the HWMP: waste storage and surveillance, technology development, disposal operations, and capital expenditures

  19. Evaluation of the deposition, translocation and pathological response of brake dust with and without added chrysotile in comparison to crocidolite asbestos following short-term inhalation: Interim results

    Energy Technology Data Exchange (ETDEWEB)

    Bernstein, David M., E-mail: davidb@itox.ch [Consultant in Toxicology, 1208 Geneva (Switzerland); Rogers, Rick, E-mail: rarogers5@yahoo.com [Rogers Imaging, Needham, MA 02494 (United States); Sepulveda, Rosalina [Rogers Imaging, Needham, MA 02494 (United States); Kunzendorf, Peter, E-mail: Peter.Kunzendorf@GSA-Ratingen.de [GSA Gesellschaft für Schadstoffanalytik mbH, D-40882 Ratingen (Germany); Bellmann, Bernd [Fraunhofer Institute for Toxicology and Experimental Medicine, D-30625 Hannover (Germany); Ernst, Heinrich, E-mail: Heinrich.ernst@item.fraunhofer.de [Fraunhofer Institute for Toxicology and Experimental Medicine, D-30625 Hannover (Germany); Phillips, James I., E-mail: jim.phillips@nioh.nhls.ac.za [National Institute for Occupational Health, National Health Laboratory Service (South Africa); Department of Biomedical Technology, Faculty of Health Sciences, University of Johannesburg (South Africa)

    2014-04-01

    Chrysotile has been frequently used in the past in manufacturing brakes and continues to be used in brakes in many countries. This study was designed to provide an understanding of the biokinetics and potential toxicology following inhalation of brake dust following short term exposure in rats. The deposition, translocation and pathological response of brake dust derived from brake pads manufactured with chrysotile were evaluated in comparison to the amphibole, crocidolite asbestos. Rats were exposed by inhalation 6 h/day for 5 days to either brake dust obtained by sanding of brake-drums manufactured with chrysotile, a mixture of chrysotile and the brake dust or crocidolite asbestos. No significant pathological response was observed at any time point in either the brake dust or chrysotile/brake dust exposure groups. The long chrysotile fibers (> 20 μm) cleared quickly with T{sub 1/2} estimated as 30 and 33 days, respectively in the brake dust and the chrysotile/brake dust exposure groups. In contrast, the long crocidolite fibers had a T{sub 1/2} > 1000 days and initiated a rapid inflammatory response in the lung following exposure resulting in a 5-fold increase in fibrotic response within 91 days. These results provide support that brake dust derived from chrysotile containing brake drums would not initiate a pathological response in the lung following short term inhalation. - Highlights: • We evaluated brake dust w/wo added chrysotile in comparison to crocidolite asbestos. • Persistence, translocation, pathological response in the lung and pleural cavity. • Chrysotile cleared rapidly from the lung while the crocidolite asbestos persisted. • No significant pathology observed at any time point in the brake-dust groups. • Crocidolite produced pathological response - Wagner 4 interstitial fibrosis by 32d.

  20. An interim report on the State of Nevada socioeconomic studies

    International Nuclear Information System (INIS)

    1989-06-01

    This Interim Report is a report on work in progress and presents findings from the research to date on the potential consequences of a repository for the citizens of Nevada. The research and findings in the Report have been subjected to rigorous peer review as part of the state's effort to insure independent, objective analysis that meets the highest professional standards. The basic research effort will continue through June 1990 and will enable the state to refine and clarify the findings presented in this Interim Report

  1. Maps of sharpness: a methodology to present results of quality control for mammographic system

    International Nuclear Information System (INIS)

    Oliveira, Henrique Jesus Quintino de; Marques, Marcio Alexandre; Frere, Annie France; Schiable, Homero; Marques, Paulo M. Azevedo; Irita, Ricardo Toshiyuki

    1996-01-01

    A new method for evaluating radiologic imaging systems quality is presented. This method intends to relate the numeric results from quality control procedures to the magnitude of shadow and penumbra in the image from given objects. This evaluation is based on a computer simulation and it can be performed for any system and any object placed in any location of the radiation field

  2. Evaluation of INPRES--Intraoperative Presentation of surgical planning and simulation results.

    Science.gov (United States)

    Salb, Tobias; Brief, Jakob; Burgert, Oliver; Gockel, Tilo; Hassfeld, Stefan; Muehling, Joachim; Dillmann, Ruediger

    2003-01-01

    In this paper we present fundamental results of the first evaluation of INPRES in a laboratory environment. While the system itself--an HMD-based approach for intraoperative augmented reality in head and neck surgery--has been described elsewhere several times, this paper will focus on methods and outcome of recently accomplished test procedures.

  3. Nuclear magnetic resonance. Present results and its application to renal pathology. Experimental study of hydronephrosis

    International Nuclear Information System (INIS)

    Bertrand, P.

    1987-01-01

    Results of proton nuclear magnetic resonance imaging and relaxation time measurement of experimental hydronephrosis in mice are presented. The study is preceded by a description of the physical principles underlying the phenomenon of nuclear magnetic resonance and of its biomedical applications and with a review of the clinical use of NMR imaging in renal pathology [fr

  4. Immediate and early non-occlusal loading of Straumann implants with a chemically modified surface (SLActive) in the posterior mandible and maxilla: interim results from a prospective multicenter randomized-controlled study.

    Science.gov (United States)

    Zöllner, Axel; Ganeles, Jeffrey; Korostoff, Jonathan; Guerra, Fernando; Krafft, Tim; Brägger, Urs

    2008-05-01

    Immediate and early loading of dental implants can simplify treatment and increase overall patient satisfaction. The purpose of this 3-year prospective randomized-controlled multicenter study was to assess the differences in survival rates and bone level changes between immediately and early-loaded implants with a new chemically modified surface (SLActive). This investigation shows interim results obtained after 5 months. Patients > or =18 years of age missing at least one tooth in the posterior maxilla or mandible were enrolled in the study. Following implant placement, patients received a temporary restoration either on the day of surgery (immediate loading) or 28-34 days after surgery (early loading); restorations consisted of single crowns or two to four unit fixed dental prostheses. Permanent restorations were placed 20-23 weeks following surgery. The primary efficacy variable was change in bone level (assessed by standardized radiographs) from baseline to 5 months; secondary variables included implant survival and success rates. A total of 266 patients were enrolled (118 males and 148 females), and a total of 383 implants were placed (197 and 186 in the immediate and early loading groups, respectively). Mean patient age was 46.3+/-12.8 years. After 5 months, implant survival rates were 98% in the immediate group and 97% in the early group. Mean bone level change from baseline was 0.81+/-0.89 mm in the immediate group and 0.56+/-0.73 mm in the early group (Pimplants with an SLActive can be used predictably in time-critical (early or immediate) loading treatment protocols when appropriate patient selection criteria are observed. The mean bone level changes observed from baseline to 5 months (0.56 and 0.81 mm) corresponded to physiological observations from other studies, i.e., were not clinically significant. The presence of a significant center effect and treatment x center interaction indicated that the differences in bone level changes between the two groups

  5. Radiation shielding and dose rate evaluation at the interim storage facility for spent fuel from Cernavoda NPP

    International Nuclear Information System (INIS)

    Stanciu, Marcela; Mateescu, Silvia; Pantazi, Doina; Penescu, Maria

    2000-01-01

    At present studies necessary to license the Interim Storage Facility for the Spent Fuel (CANDU type) from Cernavoda NPP are developed in our country.The spent fuel from Cernavoda NPP is discharged into Spent Fuel Bay in Service Building of the plant, where it remains several years for cooling. After this period, the bundles of spent fuel are to be transferred to the Interim Storage Facility.The dry interim storage solution seems to be the most appropriate variant for Cernavoda NPP.The design of the Spent Fuel Interim Storage Facility must meet the applicable safety requirements in order to ensure radiological protection of the personnel, public and environment during all phases of the facility achievement. In this paper we intend to present the calculation of radiation shielding at the spent fuel interim storage facility for two technical solutions: - Concrete Monolithic Module and Concrete Storage Cask. In order to quantify the fuel composition after irradiation, the isotope generation and depletion code ORIGEN 2.1 has been used, taking into account a cooling time of 7 years and 9 years, respectively, for these two variants. The shielding calculations have been performed using the computer codes QAD-5K and MICROSHIELD-4. The evaluations refer only to gamma radiation because the resulting neutron source (from (α,n) reactions and spontaneous fission) is insignificant as compared to the gamma source. The final results consist in the minimum thickness of the shielding and the corresponding external dose rates, ensuring a design average dose rate based on national and international regulations. (authors)

  6. Sequential interim analyses of survival data in DNA microarray experiments

    Directory of Open Access Journals (Sweden)

    Jung Klaus

    2011-04-01

    Full Text Available Abstract Background Discovery of biomarkers that are correlated with therapy response and thus with survival is an important goal of medical research on severe diseases, e.g. cancer. Frequently, microarray studies are performed to identify genes of which the expression levels in pretherapeutic tissue samples are correlated to survival times of patients. Typically, such a study can take several years until the full planned sample size is available. Therefore, interim analyses are desirable, offering the possibility of stopping the study earlier, or of performing additional laboratory experiments to validate the role of the detected genes. While many methods correcting the multiple testing bias introduced by interim analyses have been proposed for studies of one single feature, there are still open questions about interim analyses of multiple features, particularly of high-dimensional microarray data, where the number of features clearly exceeds the number of samples. Therefore, we examine false discovery rates and power rates in microarray experiments performed during interim analyses of survival studies. In addition, the early stopping based on interim results of such studies is evaluated. As stop criterion we employ the achieved average power rate, i.e. the proportion of detected true positives, for which a new estimator is derived and compared to existing estimators. Results In a simulation study, pre-specified levels of the false discovery rate are maintained in each interim analysis, where reduced levels as used in classical group sequential designs of one single feature are not necessary. Average power rates increase with each interim analysis, and many studies can be stopped prior to their planned end when a certain pre-specified power rate is achieved. The new estimator for the power rate slightly deviates from the true power rate but is comparable to other estimators. Conclusions Interim analyses of microarray experiments can provide

  7. 8 May 2014 - W. Watson-Wright, Assistant Director General and Executive Secretary UNESCO Intergovernmental Oceanographic Commission Assistant Director-General for the Natural Sciences Sector ad interim visiting the CMS cavern with CMS Collaboration Deputy Spkokesperson K. Borras. Adviser to the Director-General, in charge of Relations with International Organisations M. Bona present throughout.

    CERN Multimedia

    Brice, Maximilien

    2014-01-01

    Ms Wendy Watson-Wright Assistant Director General and Executive Secretary UNESCO Intergovernmental Oceanographic Commission Assistant Director-General for the Natural Sciences Sector ad interim UNESCO

  8. Interim FEP report for the safety assessment SR-Can

    International Nuclear Information System (INIS)

    Skagius, Kristina

    2004-08-01

    level. This latter group of FEPs is also documented in the SR-Can version of the FEP database. The further processing of the initial state FEPs revealed that those FEPs that are not covered by the description of the repository design or by the site description, concern deviations from the intended initial state as a consequence of undetected mishaps, sabotage etc. These FEPs were propagated to the selection of scenarios. Relevant process FEPs from the audit were used to update the SR 97 set of internal processes for the engineered barrier system and the geosphere. The resulting SR-Can set of processes for the buffer are documented in the interim version of the SR-Can Process report and as process headings in the SR-Can interim version of the FEP database. Preliminary lists with SR-Can processes for the other system components are presently available in the interim version of the FEP database, but these lists will be further processed and documented in the final version of the SR-Can Process report. External FEPs from the audit were checked against the plans for managing these issues in SR-Can. Climate and large-scale geological FEPs were compared against the plans for modelling these phenomena and the handling of future human actions were compared to the handling in SR 97, which forms the basis for the handling in SR-Can. The coverage was found satisfactory. The results are not documented in the interim version of the SR-Can database, but will be so in the final version of the SR-Can database

  9. Some GCM simulation results on present and possible future climate in northern Europe

    Energy Technology Data Exchange (ETDEWEB)

    Raeisaenen, J. [Helsinki Univ. (Finland). Dept. of Meteorology

    1995-12-31

    The Intergovernmental Panel on Climate Change initiated in 1993 a project entitled `Evaluation of Regional Climate Simulations`. The two basic aims of this project were to assess the skill of current general circulation models (GCMs) in simulating present climate at a regional level and to intercompare the regional response of various GCMs to increased greenhouse gas concentrations. The public data base established for the comparison included simulation results from several modelling centres, but most of the data were available in the form of time-averaged seasonal means only, and important quantities like precipitation were totally lacking in many cases. This presentation summarizes the intercomparison results for surface air temperature and sea level pressure in northern Europe. The quality of the control simulations and the response of the models to increased CO{sub 2} are addressed in both winter (December-February) and summer (June-August)

  10. Primer for the Interim Chair

    Science.gov (United States)

    Soltys, Stephen M.

    2011-01-01

    Objective: Being successful in the role of an Interim Chair requires an approach to transitional leadership that is different from that of individuals filling the Chair role permanently. This article reviews pertinent literature on the topic. Method: The author reviewed the literature, cited pertinent articles, and supplemented with personal…

  11. The Homestake Interim Laboratory and Homestake DUSEL

    Science.gov (United States)

    Lesko, Kevin T.

    2011-12-01

    developing the Homestake Interim Laboratory and evolving this facility into DUSEL are presented.

  12. The Homestake Interim Laboratory and Homestake DUSEL

    International Nuclear Information System (INIS)

    Lesko, Kevin T.

    2011-01-01

    developing the Homestake Interim Laboratory and evolving this facility into DUSEL are presented.

  13. Presentations from the Aeroelastic Workshop - latest results from AeroOpt

    Energy Technology Data Exchange (ETDEWEB)

    Hartvig Hansen, M. (ed.)

    2011-10-15

    This report contains the slides of the presentations at the Aeroelastic Workshop held at Risoe-DTU for the wind energy industry in Denmark on October 27, 2011. The scientific part of the agenda at this workshop was 1) Detailed and reduced models of dynamic mooring system (Anders M. Hansen). 2) Bend-twist coupling investigation in HAWC2 (Taeseong Kim). 3) Q3UIC - A new aerodynamic airfoil tool including rotational effects (Nestor R. Garcia). 4) Influence of up-scaling on loads, control and aerodynamic modeling (Helge Aa. Madsen). 5) Aerodynamic damping of lateral tower vibrations (Bjarne S. Kallesoee). 6) Open- and closed-loop aeroservoelastic analysis with HAWCStab2 (Morten H. Hansen). 7) Design and test of a thick, flatback, high-lift multielement airfoil (Frederik Zahle). The presented results are mainly obtained in the EUDP project ''Aeroelastic Optimization of MW Wind Turbines (AeroOpt)''. (Author)

  14. The presentation of plastic surgery visual data from 1816 to 1916: The evolution of reproducible results.

    Science.gov (United States)

    Freshwater, M Felix

    2016-09-01

    All scientific data should be presented with sufficient accuracy and precision so that they can be both analyzed properly and reproduced. Visual data are the foundation upon which plastic surgeons advance knowledge. We use visual data to achieve reproducible results by discerning details of procedures and differences between pre- and post-surgery images. This review highlights how the presentation of visual data evolved from 1816, when Joseph Carpue published his book on nasal reconstruction to 1916, when Captain Harold Gillies began to treat over 2000 casualties from the Battle of the Somme. It shows the frailties of human nature that led some authors such as Carl von Graefe, Joseph Pancoast and Thomas Mutter to record inaccurate methods or results that could not be reproduced, and what measures other authors such as Eduard Zeis, Johann Dieffenbach, and Gurdon Buck took to affirm the accuracy of their results. It shows how photography gradually supplanted illustration as a reference standard. Finally, it shows the efforts that some authors and originators took to authenticate and preserve their visual data in what can be considered the forerunners of clinical registries. Copyright © 2016 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

  15. Failsafe automation of Phase II clinical trial interim monitoring for stopping rules.

    Science.gov (United States)

    Day, Roger S

    2010-02-01

    In Phase II clinical trials in cancer, preventing the treatment of patients on a study when current data demonstrate that the treatment is insufficiently active or too toxic has obvious benefits, both in protecting patients and in reducing sponsor costs. Considerable efforts have gone into experimental designs for Phase II clinical trials with flexible sample size, usually implemented by early stopping rules. The intended benefits will not ensue, however, if the design is not followed. Despite the best intentions, failures can occur for many reasons. The main goal is to develop an automated system for interim monitoring, as a backup system supplementing the protocol team, to ensure that patients are protected. A secondary goal is to stimulate timely recording of patient assessments. We developed key concepts and performance needs, then designed, implemented, and deployed a software solution embedded in the clinical trials database system. The system has been in place since October 2007. One clinical trial tripped the automated monitor, resulting in e-mails that initiated statistician/investigator review in timely fashion. Several essential contributing activities still require human intervention, institutional policy decisions, and institutional commitment of resources. We believe that implementing the concepts presented here will provide greater assurance that interim monitoring plans are followed and that patients are protected from inadequate response or excessive toxicity. This approach may also facilitate wider acceptance and quicker implementation of new interim monitoring algorithms.

  16. [DESCRIPTION AND PRESENTATION OF THE RESULTS OF ELECTROENCEPHALOGRAM PROCESSING USING AN INFORMATION MODEL].

    Science.gov (United States)

    Myznikov, I L; Nabokov, N L; Rogovanov, D Yu; Khankevich, Yu R

    2016-01-01

    The paper proposes to apply the informational modeling of correlation matrix developed by I.L. Myznikov in early 1990s in neurophysiological investigations, such as electroencephalogram recording and analysis, coherence description of signals from electrodes on the head surface. The authors demonstrate information models built using the data from studies of inert gas inhalation by healthy human subjects. In the opinion of the authors, information models provide an opportunity to describe physiological processes with a high level of generalization. The procedure of presenting the EEG results holds great promise for the broad application.

  17. PRESENTING SEARCH RESULT WITH REDUCED UNWANTED WEB ADDRESSES USING FUZZY BASED APPROACH

    Directory of Open Access Journals (Sweden)

    Nancy Jasmine Goldena

    2017-07-01

    Full Text Available Big Data is now the most talked about research subject. Over the year with the internet and storage space expansions vast swaths of data are available for would be searcher. About a decade ago when a content was searched, due to minimum amount of content often you end up with accurate set of results. But nowadays most of the data, if not all are sometimes vague and not even sometime pertain to area of search it was indented to. Hence here a novel approach is presented to perform data cleaning using a simple but effective fuzzy rule to weed out data that won’t produce accurate data.

  18. Retention of long-term interim restorations with sodium fluoride enriched interim cement

    Science.gov (United States)

    Strash, Carolyn

    Purpose: Interim fixed dental prostheses, or "provisional restorations", are fabricated to restore teeth when definitive prostheses are made indirectly. Patients undergoing extensive prosthodontic treatment frequently require provisionalization for several months or years. The ideal interim cement would retain the restoration for as long as needed and still allow for ease of removal. It would also avoid recurrent caries by preventing demineralization of tooth structure. This study aims to determine if adding sodium fluoride varnish to interim cement may assist in the retention of interim restorations. Materials and methods: stainless steel dies representing a crown preparation were fabricated. Provisional crowns were milled for the dies using CAD/CAM technology. Crowns were provisionally cemented onto the dies using TempBond NE and NexTemp provisional cements as well as a mixture of TempBond NE and Duraphat fluoride varnish. Samples were stored for 24h then tested or thermocycled for 2500 or 5000 cycles before being tested. Retentive strength of each cement was recorded using a universal testing machine. Results: TempBond NE and NexTemp cements performed similarly when tested after 24h. The addition of Duraphat significantly decreased the retention when added to TempBond NE. NexTemp cement had high variability in retention over all tested time periods. Thermocycling for 2500 and 5000 cycles significantly decreased the retention of all cements. Conclusions: The addition of Duraphat fluoride varnish significantly decreased the retention of TempBond NE and is therefore not recommended for clinical use. Thermocycling significantly reduced the retention of TempBond NE and NexTemp. This may suggest that use of these cements for three months, as simulated in this study, is not recommended.

  19. Interim process report for the safety assessment SR-Can

    Energy Technology Data Exchange (ETDEWEB)

    Sellin, Patrick (ed.)

    2004-08-01

    This report is a documentation of buffer processes identified as relevant to the long-term safety of a KBS-3 repository. The report is part of the interim reporting of the safety assessment SR-Can, see further the Interim main report. The final SR-Can reporting will support SKB's application to build an Encapsulation plant for spent nuclear fuel and is to be produced in 2006. The purpose of this report is to document the scientific knowledge of the processes to a level required for an adequate treatment in the safety assessment. The documentation is thus from a scientific point of not exhaustive since such a treatment is neither necessary for the purposes of the safety assessment nor possible within the scope of an assessment. The purpose is further to determine the handling of each process in the safety assessment and to demonstrate how uncertainties are taken care of, given the suggested handling. The process documentation in the SR 97 version of the Process report is a starting point for this SR-Can interim version. As further described in the Interim main report, the list of relevant processes has been reviewed and slightly extended by comparison to other databases. Furthermore, the backfill has been included as a system part of its own, rather than being described together with the buffer as in SR 97. Apart from giving an interim account of the documentation and handling of buffer processes in SR-Can, this report is meant to serve as a template for the forthcoming documentation of processes occurring in other parts of the repository system. A complete list of processes can be found in the Interim FEP report for the safety assessment SR-Can. All material presented in this document is preliminary in nature and will possibly be updated as the SR-Can project progresses.

  20. Interim process report for the safety assessment SR-Can

    International Nuclear Information System (INIS)

    Sellin, Patrick

    2004-08-01

    This report is a documentation of buffer processes identified as relevant to the long-term safety of a KBS-3 repository. The report is part of the interim reporting of the safety assessment SR-Can, see further the Interim main report. The final SR-Can reporting will support SKB's application to build an Encapsulation plant for spent nuclear fuel and is to be produced in 2006. The purpose of this report is to document the scientific knowledge of the processes to a level required for an adequate treatment in the safety assessment. The documentation is thus from a scientific point of not exhaustive since such a treatment is neither necessary for the purposes of the safety assessment nor possible within the scope of an assessment. The purpose is further to determine the handling of each process in the safety assessment and to demonstrate how uncertainties are taken care of, given the suggested handling. The process documentation in the SR 97 version of the Process report is a starting point for this SR-Can interim version. As further described in the Interim main report, the list of relevant processes has been reviewed and slightly extended by comparison to other databases. Furthermore, the backfill has been included as a system part of its own, rather than being described together with the buffer as in SR 97. Apart from giving an interim account of the documentation and handling of buffer processes in SR-Can, this report is meant to serve as a template for the forthcoming documentation of processes occurring in other parts of the repository system. A complete list of processes can be found in the Interim FEP report for the safety assessment SR-Can. All material presented in this document is preliminary in nature and will possibly be updated as the SR-Can project progresses

  1. Delayed Presentation of Traumatic Diaphragmatic Hernia: The Evaluation of Surgical Treatment Results

    Directory of Open Access Journals (Sweden)

    Ali Sadrizadeh

    2015-06-01

    Full Text Available Introduction: Diaphragmatic hernia could be caused by congenital disorders, blunt trauma or penetrating injuries. The diagnosis of traumatic diaphragmatic hernia is normally neglected during the first presentation leading to late complications and considerably increased mortality and morbidity among the patients. Materials and Methods: In this retrospective, descriptive study, we reviewed the medical records of patients presented with traumatic diaphragmatic hernia who had undergone surgical operations between 1982-2015 in Ghaem Hospital and Omid Hospital affiliated to Mashhad University of Medical Sciences, Iran. The studied variables included age, gender, clinical symptoms, location of hernia, involved organs, type of imaging modalities, surgical techniques, length of hospital stay, mortality rate and surgical complications. Results: In this study, 38 patients were diagnosed with traumatic diaphragmatic hernia consisting of 28 men and 10 women. In total, 79% and 21% of the patients suffered from penetrating trauma and blunt trauma, respectively. In addition, left-sided, right-sided and bilateral hernias were present in 33%, 4% and 1% of the patients, respectively. The most frequently herniated organ was the stomach, and the most common clinical symptoms were abdominal pain (84% and dyspnea (53%. Initially, chest radiographs were performed on all the patients, and thoracotomy was performed to repair diaphragmatic tears in all the cases (100%. In this study, 3 patients had previously undergone Hartmann’s operation for gangrenous herniated colon, and devolvulation of gastric volvulus had also been performed on 3 patients. The main post-operative complications were reported to be pneumonia and respiratory insufficiency (2 cases, and the mean length of hospital stay was 6 days (5-8 days which was longer (1-2 months in patients with gangrenous bowel (3 patients. Furthermore, no mortality was reported during the course of hospitalization in these

  2. INPRES (intraoperative presentation of surgical planning and simulation results): augmented reality for craniofacial surgery

    Science.gov (United States)

    Salb, Tobias; Brief, Jakob; Welzel, Thomas; Giesler, Bjoern; Hassfeld, Steffan; Muehling, Joachim; Dillmann, Ruediger

    2003-05-01

    In this paper we present recent developments and pre-clinical validation results of our approach for augmented reality (AR, for short) in craniofacial surgery. A commercial Sony Glasstron display is used for optical see-through overlay of surgical planning and simulation results with a patient inside the operation room (OR). For the tracking of the glasses, of the patient and of various medical instruments an NDI Polaris system is used as standard solution. A complementary inside-out navigation approach has been realized with a panoramic camera. This device is mounted on the head of the surgeon for tracking of fiducials placed on the walls of the OR. Further tasks described include the calibration of the head-mounted display (HMD), the registration of virtual objects with the real world and the detection of occlusions in the object overlay with help of two miniature CCD cameras. The evaluation of our work took place in the laboratory environment and showed promising results. Future work will concentrate on the optimization of the technical features of the prototype and on the development of a system for everyday clinical use.

  3. An uncommon dental presentation during pregnancy resulting from multiple eating disorders: pica and bulimia: case report.

    Science.gov (United States)

    Johnson, Cleverick D; Koh, Sheila H; Shynett, Betty; Koh, Jason; Johnson, Claudette

    2006-01-01

    Pica is a compulsive eating disorder involving non-nutritive substances. The etiology of this eating disorder is unknown but it often is associated with subclinical mineral deficiencies. This article focuses on the simultaneous occurrence of two types of eating disorders, the co-existence of depression during four pregnancies, and the resulting dental clinical implications. The literature is substantial enough to support a possible etiological association between these eating disorders and depression during pregnancy. Associations between eating psychopathology, depression, and anxiety have been described consistently. The diagnosis of pica and the dental treatment related to it are not a common part of most dental practices; knowing the clinical features and detecting the condition depend on careful questioning and diligence. At present, no one has described the physiologic or psychological basis for pica. This article reviews the published literature pertaining to pica, specifically pagophagia.

  4. Presentation of main results of Phase I of the SMPR project initiation study

    International Nuclear Information System (INIS)

    Wald, F.

    1986-01-01

    As a result of a first Technical Committee Meeting held in Vienna in August 1983 the IAEA launched a new SMPR Project Initiation Study with the objective of surveying the available designs, examining the major factors influencing the decision-making processes in developing countries and thereby also arriving at an estimate of the potential market. The Nuclear Energy Agency of OECD offered its assistance in making a study of the potential market in industrialized countries. Two questionnaires were used to obtain information from potential suppliers and buyers. Suppliers responded with an overwhelming 23 design concepts which could be offered for export but with varying levels of readiness and provenness. From potential buyers 17 responses were received, 16 of which were from the developing countries. The analysis of the responses which was done by the Agency with the help of experts from Member States gave the basis for a draft report including the OECD/NEA part. This draft was discussed during a second Technical Committee Meeting held in Vienna in March 1985. The meeting was characterized by a strong supplier interest but also by hesitation of potential buyers to make any kind of commitments relating to the market introduction of SMPRs. All new information has been incorporated into the report together with a number of expressed comments, especially related to the presentation of the economics of SMPRs, the necessity of a reference plant, provenness of major components and systems etc. The results of the study are presented here with direct reference to the SMPR supply situation and the potential market for SMPRs in terms of the decision-making factors: the financial factors, the economical factors, and the technological factors were identified as the most important ones. The economic competitiveness is not the only decision-making factor and consequently it was decided to end the general study called Phase I by the publication of a report. Specific case studies

  5. Recent results from Fermilab E-687, charm particle decays, lifetimes and photoproduction dynamics: A compilation results presented at DPF 1994

    International Nuclear Information System (INIS)

    1994-10-01

    This report contains papers on the following topics: Recent results on the semi-leptonic decay Decay D 0 → K - μ + ν μ ; charmed mesons; observation of the Decay Ω c 0 Σ + K - K - φ + ; the physics of charm lifetimes; and photoproduction of charmed hadrons. These papers have been cataloged separately

  6. Interim Bayesian Persuasion: First Steps

    OpenAIRE

    Perez, Eduardo

    2015-01-01

    This paper makes a first attempt at building a theory of interim Bayesian persuasion. I work in a minimalist model where a low or high type sender seeks validation from a receiver who is willing to validate high types exclusively. After learning her type, the sender chooses a complete conditional information structure for the receiver from a possibly restricted feasible set. I suggest a solution to this game that takes into account the signaling potential of the sender's choice.

  7. Presentation of automated procedural guidance in surgical simulation: results of two randomised controlled trials.

    Science.gov (United States)

    Wijewickrema, S; Zhou, Y; Ioannou, I; Copson, B; Piromchai, P; Yu, C; Briggs, R; Bailey, J; Kennedy, G; O'Leary, S

    2018-03-01

    To investigate the effectiveness and usability of automated procedural guidance during virtual temporal bone surgery. Two randomised controlled trials were performed to evaluate the effectiveness, for medical students, of two presentation modalities of automated real-time procedural guidance in virtual reality simulation: full and step-by-step visual presentation of drillable areas. Presentation modality effectiveness was determined through a comparison of participants' dissection quality, evaluated by a blinded otologist, using a validated assessment scale. While the provision of automated guidance on procedure improved performance (full presentation, p = 0.03; step-by-step presentation, p presentation modalities was vastly different (full presentation, 3.73 per cent; step-by-step presentation, 60.40 per cent). Automated procedural guidance in virtual temporal bone surgery is effective in improving trainee performance. Step-by-step presentation of procedural guidance was engaging, and therefore more likely to be used by the participants.

  8. Rosiglitazone evaluated for cardiovascular outcomes--an interim analysis

    DEFF Research Database (Denmark)

    Home, Philip D; Pocock, Stuart J; Beck-Nielsen, Henning

    2007-01-01

    group). The primary end point was hospitalization or death from cardiovascular causes. RESULTS: Because the mean follow-up was only 3.75 years, our interim analysis had limited statistical power to detect treatment differences. A total of 217 patients in the rosiglitazone group and 202 patients...

  9. Safety and immunogenicity of one versus two doses of Takeda's tetravalent dengue vaccine in children in Asia and Latin America: interim results from a phase 2, randomised, placebo-controlled study.

    Science.gov (United States)

    Sáez-Llorens, Xavier; Tricou, Vianney; Yu, Delia; Rivera, Luis; Tuboi, Suely; Garbes, Pedro; Borkowski, Astrid; Wallace, Derek

    2017-06-01

    Dengue is the most common mosquito-borne viral disease in human beings, and vector control has not halted its spread worldwide. A dengue vaccine for individuals aged 9 years and older has been licensed, but there remains urgent medical need for a vaccine that is safe and effective against all four dengue virus serotypes (DENV-1-4) in recipients of all ages. Here, we present the preplanned interim analyses at 6 months of a tetravalent dengue vaccine candidate (TDV), which is comprised of an attenuated DENV-2 virus strain (TDV-2) and three chimeric viruses containing the premembrane and envelope protein genes of DENV-1, DENV-3, and DENV-4 genetically engineered into the attenuated TDV-2 genome backbone (TDV-1, TDV-3, and TDV-4). An ongoing phase 2, randomised, double-blind, placebo-controlled trial of a TDV is being done at three sites in dengue-endemic countries (Dominican Republic, Panama, and the Philippines) to determine its safety and immunogenicity over 48 months in healthy participants aged 2-17 years who were randomly assigned (1:2:5:1) using an interactive web response system (stratified by age) to subcutaneous TDV injection (one 0·5 mL dose containing 2·5 × 10 4 plaque-forming units [PFU] of TDV-1; 6·3 × 10 3 PFU of TDV-2; 3·2 × 10 4 PFU of TDV-3; and 4·0 × 10 5 PFU of TDV-4) in different dose schedules (two-dose regimen at 0 and 3 months, one dose at 0 months, or one dose at 0 months and a booster at 12 months) or placebo. The primary endpoint of this 6 month interim analysis was geometric mean titres (GMTs) of neutralising antibodies against DENV-1-4 in the per-protocol immunogenicity subset at 1 month, 3 months, and 6 months after the first injection. Safety was assessed as a secondary outcome as percentage of participants with serious adverse events in all participants who were injected (safety set), and solicited and unsolicited adverse events (immunogenicity subset). This trial is registered with ClinicalTrials.gov, number NCT

  10. Aerosol retrieval algorithm for MERIS: Description of concept and presenting results

    Science.gov (United States)

    Kosmale, Miriam; Kolmonen, Pekka; Popp, Thomas

    2017-04-01

    The Medium Resolution Imaging Spectrometer (MERIS) has been launched in 2002 onboard the ESA Envisat satellite and was providing data until Envisat's end in 2012. The MERIS spectrometer was designed primarily for surface and land scientific applications and measured reflected solar radiation in 15 channels from 400-900nm. Based on the work of Sayer and Hsu for SeaWiFS, an aerosol retrieval for MERIS was developed as part of the ESA Aerosol_cci project. The high spectral resolution of the instrument provides capability for retrieving aerosols. The algorithm can be transferred also to the OLCI measurements operating onboard the Sentinel-3 satellites since 2015. The retrieval code uses a Look-Up-Table (LUT) approach to speed up the calculations. The LUTs are calculated with the radiative transfer code LibRadtran (Meyer und Kylling, 2005). In minimizing the differences of satellite measurements with forward simulations, with Levenberg-Marquardt as the mathematical approach, the aerosol loading of the satellite measurement is inferred. As basis for the algorithm, a MERIS new cloud detection system (exploiting blue to near infrared channels) was defined, as well as a 16-day moving average surface albedo database. The presentation will describe the general concept of the retrieval algorithm and show results of aerosol properties retrieved from the MERIS measurements. An information content analysis is used to assess the general capability of retrieving aerosol optical depth (AOD) from the MERIS channels. Challenges concerning the retrieval algorithm and its input data will be discussed. Comparisons with external datasets will be given, either for the cloud mask, the surface database as well as the final AOD product. Results of the aerosol product will be presented together with a discussion on its quality triggered by validation with AERONET measurements. Mayer, B. & Kylling, A. Technical note: The libRadtran software package for radiative transfer calculations

  11. Monitoring and Leak testig of wwer-440 fuel assemblies in Slovak wet interim spent fuel storage facility

    Directory of Open Access Journals (Sweden)

    Miroslav Božik

    2007-01-01

    Full Text Available An accelerated monitoring system designed for the Slovak wet interim spent fuel storage facility in NPP Jaslovské Bohunice bases on the newly designed “cesium detectors” is presented in the paper. Since 1999, leak tests of WWER-440 fuel assemblies are provided by a special leak tightness detection system “Sipping in Pool” delivered by the Framatome-anp with external heating for the precise defects determination. Although this system seems to be very effective, the detection time of all fuel assemblies in one storage pool is too long. Therefore, a new “on-line” detection system, based on the new sorbent NIFSIL for an effective 134Cs and 137Cs activity was developed. The design of this detection system and its application possibility in Slovak wet interim spent fuel storage facility as well as preliminary results are presented.

  12. EDF - 2005 Consolidated Annual Results - Analysts' Presentation. Consolidated financial statements at December 31, 2005

    International Nuclear Information System (INIS)

    2006-01-01

    As the world's biggest electricity generator, the EDF Group covers every sector of expertise, from generation to trading and transmission grids. EDF builds on the expertise of its people, its R and D and engineering skills, its experience as a leading industry operator and the attentive support of its customers to deliver competitive solutions that successfully reconcile economic growth with climate protection. This document presents the 2005 annual results and Consolidated financial statements of the Group at 31 December 2005: Consolidated income statements, consolidated balance sheets, consolidated cash flow statements, variation in consolidated equity, notes (group accounting policies, impact of first-time application of IFRs, transition to standards IAS 32 and 39 concerning financial instruments, summary of accounting and valuation methods, public distribution concessions in France, significant events and transactions of 2005, impact of the law of august 9, 2004 on comparability, changes in the scope of consolidation, segment reporting, sales, fuel and energy purchases, other external expenses, contractual obligations and commitments entered into in the course of business, personnel expenses, other operating income and expenses, other income and expenses, financial result, income taxes, basic earnings per share and diluted earnings per share, goodwill, other intangible assets, property, plant and equipment, investments in companies accounted for under the equity method, financial assets, inventories, including work-in-process, trade receivables, other receivables, cash and cash equivalents, available-for-sale assets and liabilities, equity, provisions, special concession liabilities, current and non-current financial liabilities, derivatives, other liabilities, related parties, greenhouse gas emission quotas, environment, subsequent events, scope of consolidation

  13. Burn site groundwater interim measures work plan.

    Energy Technology Data Exchange (ETDEWEB)

    Witt, Jonathan L. (North Wind, Inc., Idaho Falls, ID); Hall, Kevin A. (North Wind, Inc., Idaho Falls, ID)

    2005-05-01

    This Work Plan identifies and outlines interim measures to address nitrate contamination in groundwater at the Burn Site, Sandia National Laboratories/New Mexico. The New Mexico Environment Department has required implementation of interim measures for nitrate-contaminated groundwater at the Burn Site. The purpose of interim measures is to prevent human or environmental exposure to nitrate-contaminated groundwater originating from the Burn Site. This Work Plan details a summary of current information about the Burn Site, interim measures activities for stabilization, and project management responsibilities to accomplish this purpose.

  14. The San Fernando Automatic Meridian Circle in Argentina: Present state, FIRS T results and future plans.

    Science.gov (United States)

    Mallamaci, C. C.; Muiqos, J. L.; Pirez, J. A.; Belizsn, F.; Vallejo, M.; Gallego, M.; Marmolejo, L. F.; Navarro, J. L.; Sedeqo, J. A.

    1998-11-01

    Thanks to a Co-operation and Support Agreement, signed between the National University of San Juan (Argentina) and the Royal Institute and Observatory of the Army in San Fernando (Cadiz, Spain), an Automatic Meridian Circle was settled up in the province of San Juan, in July of 1996. This instrument is "twin" of another already installed in El Roque de los Muchachos Observatory (Astrophysical Institute of Canaries) in La Palma Island. In the current state of the instrument, with a photomultiplier as main detector, it is possible to observe about 400-600 stars per night (depending on the time of the year, summer or winter) up to magnitude 15.5, approximately. At present we are carrying out an observation program of stars and Solar System bodies (planets, satellites and asteroids), whose results will yield our first catalogue of positions of celestial objects. As by-product of the observations, the catalogue will also include the magnitudes of the observed objects, obtained by means of the photomultiplier counts. The stability of the instrument and the quality of the observations are good, though we keep working in fine adjustments of the telescope. The future plans for the telescope include the complete renewal of the computer system and the replacement of the photomultiplier and the slit micrometer for a CCD camera. The first of these changes implies the substitution of the current 2113 and A700 HP computers by a modern Pentium PC, and will be made by the end of 1998. The replacement of the sensor will be carried out, probably, during the first semester of 1999. The latter improvement will introduce a substantial change in the philosophy of observation and reduction, and will bring about the whole renewal of the software. All these changes will considerably increase the accuracy in the operation of the instrument, specially because of the significant reduction in mechanical component, since the mechanical movements decrease to a minimum. The handling of the

  15. German Approach for the Transport of Spent Fuel Packages after Interim Storage

    International Nuclear Information System (INIS)

    Wille, Frank; Wolff, Dietmar; Droste, Bernhard; Voelzke, Holger

    2014-01-01

    In Germany the concept of dry interim storage of spent nuclear fuel in dual purpose metal casks is implemented, currently for periods of up to 40 years. The casks being used have an approved package design in accordance with the international transport regulations. The license for dry storage is granted on the German Atomic Energy Act with respect to the recently (in 2012) revised 'Guidelines for dry cask storage of spent nuclear fuel and heat-generating waste' by the German Waste management Commission (ESK) which are very similar to the former RSK (reactor safety commission) guidelines. For transport on public routes between or after long term interim storage periods, it has to be ensured that the transport and storage casks fulfil the specifications of the transport approval or other sufficient properties which satisfy the proofs for the compliance of the safety objectives at that time. In recent years the validation period of transport approval certificates for manufactured, loaded and stored packages were discussed among authorities and applicants. A case dependent system of 3, 5 and 10 years was established. There are consequences for the safety cases in the Package Design Safety Report including evaluation of long term behavior of components and specific operating procedures of the package. Present research and knowledge concerning the long term behavior of transport and storage cask components have to be consulted as well as experiences from interim cask storage operations. Challenges in the safety assessment are e.g. the behavior of aged metal and elastomeric seals under IAEA test conditions to ensure that the results of drop tests can be transferred to the compliance of the safety objectives at the time of transport after the interim storage period (aged package). Assessment methods for the material compatibility, the behavior of fuel assemblies and the aging behavior of shielding parts are issues as well. This paper describes the state

  16. Subsurface Interim Measures/Interim Remedial Action Plan/Environmental Assessment and Decision Document, Operable Unit No. 2

    International Nuclear Information System (INIS)

    1992-01-01

    The subject Interim Measures/Interim Remedial Action plan/Environmental Assessment (IM/IRAP/EA) addresses residual free-phase volatile organic compound (VOC) contamination suspected in the subsurface within an area identified as Operable Unit No. 2 (OU2). This IM/IRAP/EA also addresses radionuclide contamination beneath the 903 Pad at OU2. Although subsurface VOC and radionuclide contamination on represent a source of OU2 ground-water contamination, they pose no immediate threat to public health or the environment. This IM/IRAP/EA identifies and evaluates interim remedial actions for removal of residual free-phase VOC contamination from three different subsurface environments at OU2. The term ''residual'' refers to the non-aqueous phase contamination remaining in the soil matrix (by capillary force) subsequent to the passage of non-aqueous or free-phase liquid through the subsurface. In addition to the proposed actions, this IM/IRAP/EA presents an assessment of the No Action Alternative. This document also considers an interim remedial action for the removal of radionuclides from beneath the 903 Pad

  17. New York State interim waste management cost evaluation

    International Nuclear Information System (INIS)

    Ma, M.S.; Watts, R.J.; Jorgensen, J.R.; Rochester Gas and Electric Corp., NY)

    1985-01-01

    The purpose of this study is to investigate and quantify the comparative costs associated with including or excluding Class A utility wastes at a centralized interim waste management facility in New York State. The objective of the study is to assess the unit costs and total statewide costs associated with two distinct scenarios: (1) the case where non-utility Class A LLRW is received, incinerated and stored at the centralized interim facility, and utility Class A wastes are held without incineration at respective nuclear power plant interim onsite facilities without incineration; and (2) the alternative case where both utility and non-utility Class A wastes are accepted, incinerated and stored at the centralized facility. Unit costs to waste generators are estimated for each of the two cases described. This is followed by an estimation of the statewide cost impact to the public. The cost impact represents the cost differential resulting from the exclusion of utility Class A waste from the centralized NYS interim waste management facility. The principal factors comprising the cost differential include (1) higher unit disposal fees charged to non-utility waste generators, which are passed along in the costs of products and services; and (2) costs to utilities due to construction of additional onsite storage capacity, which in turn are charged to electric rate payers

  18. Locating Interim Assessments within Teachers' Assessment Practice

    Science.gov (United States)

    Riggan, Matthew; Olah, Leslie Nabors

    2011-01-01

    Promising research on the teaching and learning impact of classroom-embedded formative assessment has spawned interest in a broader array of assessment tools and practices, including interim assessment. Although researchers have begun to explore the impact of interim assessments in the classroom, like other assessment tools and practices, they…

  19. Addendum to IFMIF-CDA interim report

    International Nuclear Information System (INIS)

    Maekawa, Hiroshi; Ida, Mizuho

    1996-08-01

    During the second IFMIF-CDA Design Integration Workshop, the conceptual design and contents of 'IFMIF-CDA Interim Report' were examined and discussed at both general and group meetings. Based on these discussion, the final IFMIF-CDA Report will be modified from the 'Interim Report'. This report describes the outline of these modification. (author)

  20. Guidelines for Preparing Interim Technical Reports

    International Development Research Centre (IDRC) Digital Library (Canada)

    IDRC CRDI

    The interim technical report explains what was achieved with the money and time spent on a project during a specific reporting period. The interim report specifically .... o knowledge creation (new knowledge embodied in forms other than publications or reports: new technologies, new methodologies, new curricula, new ...

  1. DQO Summary Report for 105-N/109-N Interim Safe Storage Project Waste Characterization

    Energy Technology Data Exchange (ETDEWEB)

    T. A. Lee

    2005-09-15

    The DQO summary report provides the results of the DQO process completed for waste characterization activities for the 105-N/109-N Reactor Interim Safe Storage Project including decommission, deactivate, decontaminate, and demolish activities for six associated buildings.

  2. DQO Summary Report for 105-N/109-N Interim Safe Storage Project Waste Characterization

    International Nuclear Information System (INIS)

    Lee, T.A.

    2005-01-01

    The DQO summary report provides the results of the DQO process completed for waste characterization activities for the 105-N/109-N Reactor Interim Safe Storage Project including decommission, deactivate, decontaminate, and demolish activities for six associated buildings.

  3. Vet Centers. Interim final rule.

    Science.gov (United States)

    2015-08-04

    The Department of Veterans Affairs (VA) is amending its medical regulation that governs Vet Center services. The National Defense Authorization Act for Fiscal Year 2013 (the 2013 Act) requires Vet Centers to provide readjustment counseling services to broader groups of veterans, members of the Armed Forces, including a member of a reserve component of the Armed Forces, and family members of such veterans and members. This interim final rule amends regulatory criteria to conform to the 2013 Act, to include new and revised definitions.

  4. Fusion Breeder Program interim report

    International Nuclear Information System (INIS)

    Moir, R.; Lee, J.D.; Neef, W.

    1982-01-01

    This interim report for the FY82 Fusion Breeder Program covers work performed during the scoping phase of the study, December, 1981-February 1982. The goals for the FY82 study are the identification and development of a reference blanket concept using the fission suppression concept and the definition of a development plan to further the fusion breeder application. The context of the study is the tandem mirror reactor, but emphasis is placed upon blanket engineering. A tokamak driver and blanket concept will be selected and studied in more detail during FY83

  5. Interim main report of the safety assessment SR-Can

    International Nuclear Information System (INIS)

    Hedin, Allan

    2004-08-01

    This document is an interim report on the safety assessment SR-Can (SR in the acronym stands for Safety Report and Can is short for canister). The final SR-Can report will support SKB's application to build an Encapsulation plant for spent nuclear fuel and is to be produced in 2006. The purpose of the present interim report is to demonstrate the methodology for safety assessment so that it can be reviewed before it is used in a license application. The assessment relates to the KBS-3 disposal concept in which copper canisters with a cast iron insert containing spent nuclear fuel are surrounded by bentonite clay and deposited at approximately 500 m depth in saturated, granitic rock. Preliminary data from the Forsmark site, presently being investigated by SKB as one of the candidate for a KBS-3 repository are used to some extent as examples. However, the collected data are yet too sparse to allow an evaluation of safety for this site. An important aim of this report is to demonstrate the proper handling of requirements on the safety assessment in applicable regulations. Therefore, regulations issued by the Swedish Nuclear Power Inspectorate and the Swedish Radiation Protection Authority are duplicated in an Appendix. The principal acceptance criterion requires that 'the annual risk of harmful effects after closure does not exceed 10 -6 for a representative individual in the group exposed to the greatest risk'. 'Harmful effects' refer to cancer and hereditary effects. Following the introductory chapter 1, this report outlines the methodology for the SR-Can assessment in chapter 2, and presents in chapters 3, 4 and 5 the initial state of the system and the plans and methods for handling external influences and internal processes, respectively. Function indicators are introduced in chapter 6 and a preliminary evaluation of these is given in chapter 7. The material presented in the first seven chapters is utilised in the scenario selection in chapter 8. Hydrogeological

  6. Interim main report of the safety assessment SR-Can

    Energy Technology Data Exchange (ETDEWEB)

    Hedin, Allan (ed.) [and others

    2004-08-01

    This document is an interim report on the safety assessment SR-Can (SR in the acronym stands for Safety Report and Can is short for canister). The final SR-Can report will support SKB's application to build an Encapsulation plant for spent nuclear fuel and is to be produced in 2006. The purpose of the present interim report is to demonstrate the methodology for safety assessment so that it can be reviewed before it is used in a license application. The assessment relates to the KBS-3 disposal concept in which copper canisters with a cast iron insert containing spent nuclear fuel are surrounded by bentonite clay and deposited at approximately 500 m depth in saturated, granitic rock. Preliminary data from the Forsmark site, presently being investigated by SKB as one of the candidate for a KBS-3 repository are used to some extent as examples. However, the collected data are yet too sparse to allow an evaluation of safety for this site. An important aim of this report is to demonstrate the proper handling of requirements on the safety assessment in applicable regulations. Therefore, regulations issued by the Swedish Nuclear Power Inspectorate and the Swedish Radiation Protection Authority are duplicated in an Appendix. The principal acceptance criterion requires that 'the annual risk of harmful effects after closure does not exceed 10{sup -6} for a representative individual in the group exposed to the greatest risk'. 'Harmful effects' refer to cancer and hereditary effects. Following the introductory chapter 1, this report outlines the methodology for the SR-Can assessment in chapter 2, and presents in chapters 3, 4 and 5 the initial state of the system and the plans and methods for handling external influences and internal processes, respectively. Function indicators are introduced in chapter 6 and a preliminary evaluation of these is given in chapter 7. The material presented in the first seven chapters is utilised in the scenario selection

  7. Solid waste burial grounds interim safety analysis

    International Nuclear Information System (INIS)

    Saito, G.H.

    1994-01-01

    This Interim Safety Analysis document supports the authorization basis for the interim operation and restrictions on interim operations for the near-surface land disposal of solid waste in the Solid Waste Burial Grounds. The Solid Waste Burial Grounds Interim Safety Basis supports the upgrade progress for the safety analysis report and the technical safety requirements for the operations in the Solid Waste Burial Grounds. Accident safety analysis scenarios have been analyzed based on the significant events identified in the preliminary hazards analysis. The interim safety analysis provides an evaluation of the operations in the Solid Waste Burial Grounds to determine if the radiological and hazardous material exposures will be acceptable from an overall health and safety standpoint to the worker, the onsite personnel, the public, and the environment

  8. Solid waste burial grounds interim safety analysis

    Energy Technology Data Exchange (ETDEWEB)

    Saito, G.H.

    1994-10-01

    This Interim Safety Analysis document supports the authorization basis for the interim operation and restrictions on interim operations for the near-surface land disposal of solid waste in the Solid Waste Burial Grounds. The Solid Waste Burial Grounds Interim Safety Basis supports the upgrade progress for the safety analysis report and the technical safety requirements for the operations in the Solid Waste Burial Grounds. Accident safety analysis scenarios have been analyzed based on the significant events identified in the preliminary hazards analysis. The interim safety analysis provides an evaluation of the operations in the Solid Waste Burial Grounds to determine if the radiological and hazardous material exposures will be acceptable from an overall health and safety standpoint to the worker, the onsite personnel, the public, and the environment.

  9. Patient-oriented presentation of results of radiological procedures using DICOM-compliant DVD media

    Science.gov (United States)

    Ratib, Osman M.; Aberle, Denise R.; Goldin, Jonathan G.; Lu, David S.; Dahlbom, Magdalena; McGill, D. Ric; McCoy, J. Michael

    2003-05-01

    Some institutions have adopted digital media such as CD ROMs to provide patients and referring physicians with results of radiological procedures. These systems require a computer to review the images and lack the supporting explanations and guidance for patients to properly understand the results. We developed a hybrid DVD encoding format that combines DICOM-compliant image storage format with video streams viewable on any consumer DVD players. The addition of the video material allows radiologists to provide explanations, disclaimers and guidance to the patients regarding the results of the study. The diagnostic report is also included on the DVD as a PDF file and as a set of video frames that can be viewed on a DVD player. The native high-resolution images are also included in DICOM format on the DVD and can be accessed by any workstation equipped with a DICOM viewer. The DVD that can be reviewed on any consumer DVD player overcomes the limitation of CD ROMS that require the use of a personal computer. The results of the radiological procedures become more accessible patients that could be reluctant or unable to use a computer. Also, live video clips add a more personalized note and allow radiologists to convey important messages to the patients. This is particularly useful for self-referred screening procedures where results should always be accompanied with education material and explanations of the findings.

  10. Clinical presentation and time-course of postoperative venous thromboembolism: Results from the RIETE Registry.

    Science.gov (United States)

    Arcelus, Juan Ignacio; Monreal, Manuel; Caprini, Joseph A; Guisado, Javier Gutiérrez; Soto, Maria José; Núñez, Manuel Jesús; Alvárez, Juan Carlos

    2008-03-01

    There is little literature about the clinical presentation and time-course of postoperative venous thromboembolism (VTE) in different surgical procedures. RIETE is an ongoing, prospective registry of consecutive patients with objectively confirmed, symptomatic acute VTE. In this analysis, we analysed the baseline characteristics, thromboprophylaxis and therapeutic patterns, time-course, and three-month outcome of all patients with postoperative VTE. As of January 2006, there were 1,602 patients with postoperative VTE in RIETE: 393 (25%) after major orthopaedic surgery (145 elective hip arthroplasty, 126 knee arthroplasty, 122 hip fracture); 207 (13%) after cancer surgery; 1,002 (63%) after other procedures. The percentage of patients presenting with clinically overt pulmonary embolism (PE) (48%, 48%, and 50% respectively), the average time elapsed from surgery to VTE (22 +/- 16, 24 +/- 16, and 21 +/- 15 days, respectively), and the three-month incidence of fatal PE (1.3%, 1.4%, and 0.8%, respectively), fatal bleeding (0.8%, 1.0%, and 0.2%, respectively), or major bleeding (2.3%, 2.9%, and 2.8%, respectively) were similar in the three groups. However, the percentage of patients who had received thromboprophylaxis (96%, 76% and 52%, respectively), the duration of prophylaxis (17 +/- 9.6, 13 +/- 8.9, and 12 +/- 11 days, respectively) and the mean daily doses of low-molecular-weight heparin (4,252 +/- 1,016, 3,260 +/- 1,141, and 3,769 +/- 1,650 IU, respectively), were significantly lower in those undergoing cancer surgery or other procedures. In conclusion, the clinical presentation, time-course, and three-month outcome of VTE was similar among the different subgroups of patients, but the use of prophylaxis in patients undergoing cancer surgery or other procedures was suboptimal.

  11. Results and tasks of radiation neurology at the present-day stage

    International Nuclear Information System (INIS)

    Torubarov, F.S.

    1991-01-01

    The main stage are presented of development of radiation clinical neurology, paying attention to the contribution of Soviet clinicals in connection with assessment of possible responses at the Chernobyl accident. Neurological disorders in ARS of various degrees of severity at different periods of diseases as well as during irradiation at doses, not causing ARS development were described. The importance of clinicophysiological investigations for assessment of CNS function during the development of disease and its aftereffects was shown. The role of psychological investigations on mental abilities of persons, exposed to acute ionizing radiation was emphasized

  12. Final hazard classification and auditable safety analysis for the 105-C Reactor Interim Safe Storage Project

    International Nuclear Information System (INIS)

    Rodovsky, T.J.; Larson, A.R.; Dexheimer, D.

    1996-12-01

    This document summarizes the inventories of radioactive and hazardous materials present in the 105-C Reactor Facility and the operations associated with the Interim Safe Storage Project which includes decontamination and demolition and interim safe storage of the remaining facility. This document also establishes a final hazard classification and verifies that appropriate and adequate safety functions and controls are in place to reduce or mitigate the risk associated with those operations

  13. SMOS CATDS Level 3 products, Soil Moisture and Brightness Temperature: Presentation and results

    Science.gov (United States)

    Berthon, Lucie; Mialon, Arnaud; Bitar, Ahmad Al; Cabot, François; Bircher, Simone; Jacquette, Elsa; Quesney, Arnaud; Kerr, Yann H.

    2013-04-01

    The ESA's (European Space Agency) SMOS (Soil Moisture and Ocean Salinity) mission, operating since November 2009, is the first satellite dedicated to measuring surface soil moisture and ocean salinity. The CNES (Centre National d'Etudes Spatiales) has developed the CATDS (Centre Aval de Traitement des Données SMOS) ground segment. It provides spatial and temporal synthesis products (referred to as Level 3) of soil moisture, which are now covering the whole SMOS operation period since January 2010. These products have different time resolutions: daily products, 3-day global products (insuring a complete coverage of the Earth's surface), 10-day composite products, and monthly averaged products. Moreover, a new product provides brightness temperatures at H and V polarizations which are computed at fixed incidence angles every 5 degrees. All the CATDS products are presented in the NetCDF format on the EASE grid (Equal Area Scalable Earth grid) with a spatial resolution of ~ 25*25 km². The soil moisture Level 3 algorithm is based on ESA's Level 2 retrieval scheme with the improvement of using several overpasses (3 at most) over a 7-day window. Using many revisits is expected to improve the quality of the retrieved soil moisture. This communication aims at presenting the CATDS soil moisture and brightness temperature products as well as other geophysical parameters retrieved on the side, such as the vegetation optical depth or the dielectric constant of the surface. Furthermore, we illustrate the validation of this database, including the comparison of the Level 3 soil moisture to in-situ measurements available from various sites (Australia, US, southwest of France, Spain, Denmark, West Africa, French Alps), spanning different surface conditions.

  14. Permanent implants for lip augmentation: Results from a retrospective study and presentation of tips and tricks.

    Science.gov (United States)

    Guida, S; Mandel, V D; Farnetani, F; Manola, C M; Rubino, G; Ruzzu, S; Pellacani, G; Longo, C; Urtis, G G

    2017-05-01

    Requests for lip augmentation are increasing because of expanding media exposure and consumer needs. Temporary effects can be obtained by several techniques, but a recent procedure consisting of lip prosthesis implantation, offering a permanent result, is emerging. Accordingly, the implantation of solid lip prosthesis represents an innovation in the field of esthetic medicine and surgery. A total of 100 women with atrophic or hypoplastic lips were treated with lip implants. The treatment was performed in a single session, and controls were scheduled at fixed time intervals. A standard digital photo was used for measurement and analysis. Data concerning patient satisfaction and complications of the technique were collected and analyzed. Variations to the original technique were also discussed. Patient evaluation revealed that a permanent and natural result without discomfort for the patient and/or the partner was reached with the implantation of silicone prosthesis in the upper and/or lower lip. Swelling, bruising, and malpositions were the most frequent adverse events. A case of severe edema was reported. Practical tricks acquired through experience were discussed to prevent complications. One of the most widespreading methods for lip remodeling is hyaluronic acid injections. Nevertheless, hyaluronic acid has a variable duration, and it is not always the first choice. This context allowed for the development of other techniques such as the implantation of silicone prosthesis. The advantages of this prosthesis are as follows: safety, definitive result, and reversibility considering the possibility to remove the implanted prosthesis in the case of a request. Copyright © 2017 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

  15. [Paracelsus research past and present: basic results, frustrated attempts, new approaches].

    Science.gov (United States)

    Dilg, P

    1993-01-01

    As is well known, the Leipzig historian of medicine Karl Sudhoff inaugurated modern research on Paracelsus, providing it with a basis that has remained indispensable right down to the present. Pertinent scholarly contributions by Sudhoff date from 1887; they culminated first in the Paracelsus bibliography of 1894 and reached their fitting conclusion with the edition of Hohenheim's collected works, Abteilung 1: Medizinische, naturwissenschaftliche und philosophische Schriften; its fourteen volumes appeared between 1922 and 1933. Following the second world war the Marburg historian of religion Kurt Goldammer undertook the edition of Abteilung 2: Theologische und religionsphilosophische Schriften; this edition, building on Sudhoff's work, is likewise conceived as comprising fourteen volumes, of which six (together with a supplement), that is, half the projected total, have appeared so far (through 1986). Alongside these fundamental achievements, however, Paracelsus research in the more recent past has also been marked by a series of failed attempts. One of these is the index volume to the Sudhoff edition; it was put together under difficult circumstances, and even at the time of its appearance (1960) it failed to fully satisfy scholarly criteria. A further unsatisfactory aspect, it may be recalled, is the Paracelsus lexicon which was begun forty years ago, but which, despite the pressing need for a research tool of this kind, has still not appeared. Finally, it has not been possible, despite repeated efforts, to establish a Paracelsus institute in the sense of a centre for historical research. Under these circumstances, the continued care for what Paracelsus has bequeathed to us and the coordination of related activities have down to the present been provided for solely by the two pertinent professional societies, the Schweizerische Paracelsus-Gesellschaft (founded in 1942) and the Internationale Paracelsus-Gesellschaft (created in 1951), along with their respective

  16. Results and present status of the Japan-US collaboration on detector research and development

    International Nuclear Information System (INIS)

    Arai, Yasuo; Takahashi, Kasuke

    1985-02-01

    This is a summary report on the results of the Detector R and D work, which we have been carrying out these three years, under the Japan-U.S. collaboration on High Energy Physics. It is clear that there have been already many considerable progress and outputs in the activities, some of which are already applied to the actual detectors in various ways. It is foreseeable that more extensive development will be realized. It should also be better to emphasize that these detector R and D efforts will be very important for the further development of high energy physics in the near future. (author)

  17. Glass packages in interim storage

    International Nuclear Information System (INIS)

    Jacquet-Francillon, N.

    1994-10-01

    This report summarize the current state of knowledge concerning the behavior of type C waste packages consisting of vitrified high-level solutions produced by reprocessing spent fuel. The composition and the physical and chemical properties of the feed solutions are reviewed, and the vitrification process is described. Sodium alumino-borosilicate glass compositions are generally employed - the glass used at la Hague for LWR fuel solutions, for example, contains 45 % SiO 2 . The major physical, chemical, mechanical and thermal properties of the glass are reviewed. In order to allow their thermal power to diminish, the 3630 glass packages produced (as of January 1993) in the vitrification facilities at Marcoule and La Hague are placed in interim storage for several decades. The actual interim storage period has not been defined, as it is closely related to the concept and organization selected for the final destination of the packages: a geological repository. The glass behavior under irradiation is described. Considerable basic and applied research has been conducted to assess the aqueous leaching behavior of nuclear containment glass. The effects of various repository parameters (temperature, flow rate, nature of the environmental materials) have been investigated. The experimental findings have been used to specify a model describing the kinetics of aqueous corrosion of the glass. More generally all the ''source term'' models developed in France by the CEA or by ANDRA are summarized. (author). 152 refs., 33 figs

  18. Present status of TMI-2 plant and results of its research

    International Nuclear Information System (INIS)

    Sasaki, Sadaaki; Yokomi, Michiro.

    1987-01-01

    In the accident occurred in the TMI-2 plant on March 28, 1979, the damage was caused in the reactor core, but there scarcely was the effect on the health and safety of general public around the power station. But in USA, it was decided to collect the data on the fuel, decontamination, waste management and so on of this plant and to advance the survey and research on the safety by the analysis and evaluation of the course of the accident mainly by GPUN, EPRI, NRC and DOE. Also in Japan, it was judged that the participation in this research would be useful for improving the reliability of Japanese nuclear power plants hereafter, and the Japan-USA agreement on TMI-2 research and development project was concluded on April 16, 1984. The activity plan in TMI-2 is divided into three stages. Phase 1 is the stage of stabilization, Phase 2 is the stage of taking fuel out, and Phase 3 is the stage of cleaning. At present, Phase 2 - 3 are in progress, and the taking-out and transport of fuel and decontamination are carried out. After finishing Phase 3, the TMI-2 plant is placed in the state of monitoring and preservation, which is scheduled in September, 1988. The final disposal of the plant will be determined thereafter. Decontamination, treatment of contaminated water and wastes, taking-out and transport of fuel, state of the reactor core and others are reported. (Kako, I.)

  19. The present status and future growth of maintenance in US manufacturing: results from a pilot survey

    Directory of Open Access Journals (Sweden)

    Jin Xiaoning

    2016-01-01

    Full Text Available A research study was conducted (1 to examine the practices employed by US manufacturers to achieve productivity goals and (2 to understand what level of intelligent maintenance technologies and strategies are being incorporated into these practices. This study found that the effectiveness and choice of maintenance strategy were strongly correlated to the size of the manufacturing enterprise; there were large differences in adoption of advanced maintenance practices and diagnostics and prognostics technologies between small and medium-sized enterprises (SMEs. Despite their greater adoption of maintenance practices and technologies, large manufacturing organizations have had only modest success with respect to diagnostics and prognostics and preventive maintenance projects. The varying degrees of success with respect to preventative maintenance programs highlight the opportunity for larger manufacturers to improve their maintenance practices and use of advanced prognostics and health management (PHM technology. The future outlook for manufacturing PHM technology among the manufacturing organizations considered in this study was overwhelmingly positive; many manufacturing organizations have current and planned projects in this area. Given the current modest state of implementation and positive outlook for this technology, gaps, future trends, and roadmaps for manufacturing PHM and maintenance strategy are presented.

  20. The present status and future growth of maintenance in US manufacturing: results from a pilot survey.

    Science.gov (United States)

    Jin, Xiaoning; Siegel, David; Weiss, Brian A; Gamel, Ellen; Wang, Wei; Lee, Jay; Ni, Jun

    A research study was conducted (1) to examine the practices employed by US manufacturers to achieve productivity goals and (2) to understand what level of intelligent maintenance technologies and strategies are being incorporated into these practices. This study found that the effectiveness and choice of maintenance strategy were strongly correlated to the size of the manufacturing enterprise; there were large differences in adoption of advanced maintenance practices and diagnostics and prognostics technologies between small and medium-sized enterprises (SMEs). Despite their greater adoption of maintenance practices and technologies, large manufacturing organizations have had only modest success with respect to diagnostics and prognostics and preventive maintenance projects. The varying degrees of success with respect to preventative maintenance programs highlight the opportunity for larger manufacturers to improve their maintenance practices and use of advanced prognostics and health management (PHM) technology. The future outlook for manufacturing PHM technology among the manufacturing organizations considered in this study was overwhelmingly positive; many manufacturing organizations have current and planned projects in this area. Given the current modest state of implementation and positive outlook for this technology, gaps, future trends, and roadmaps for manufacturing PHM and maintenance strategy are presented.

  1. Probing of Hermean Exosphere by ultraviolet spectroscopy: Instrument presentation, calibration philosophy and first lights results

    Science.gov (United States)

    Mariscal, J. F.; Rouanet, N.; Maria, J. L.; Quémerais, E.; Mine, P. O.; Zuppella, P.; Suman, M.; Nicolosi, P.; Pelizzo, M. G.; Yoshikawa, I.; Yoshioka, K.; Murakami, G.

    2017-11-01

    PHEBUS (Probing of Hermean Exosphere by Ultraviolet Spectroscopy) is a double spectrometer for the Extreme Ultraviolet range (55-155 nm) and the Far Ultraviolet range (145-315 nm) dedicated to the characterization of Mercury's exosphere composition and dynamics, and surface-exosphere connections. PHEBUS is part of the ESA BepiColombo cornerstone mission payload devoted to the study of Mercury. The BepiColombo mission consists of two spacecrafts: the Mercury Magnetospheric Orbiter (MMO) and the Mercury Planetary Orbiter (MPO) on which PHEBUS will be mounted. PHEBUS is a French-led instrument implemented in a cooperative scheme involving Japan (detectors), Russia (scanner) and Italy (ground calibration). Before launch, PHEBUS team want to perform a full absolute calibration on ground, in addition to calibrations which will be made in-flight, in order to know the instrument's response as precisely as possible. Instrument overview and calibration philosophy are introduced along with the first lights results observed by a first prototype.

  2. Interim Hanford Waste Management Technology Plan

    International Nuclear Information System (INIS)

    1985-09-01

    The Interim Hanford Waste Management Technology Plan (HWMTP) is a companion document to the Interim Hanford Waste Management Plan (HWMP). A reference plan for management and disposal of all existing and certain projected future radioactive Hanford Site Defense Wastes (HSDW) is described and discussed in the HWMP. Implementation of the reference plan requires that various open technical issues be satisfactorily resolved. The principal purpose of the HWMTP is to present detailed descriptions of the technology which must be developed to close each of the technical issues associated with the reference plan identified in the HWMP. If alternative plans are followed, however, technology development efforts including costs and schedules must be changed accordingly. Technical issues addressed in the HWMTP and HWMP are those which relate to disposal of single-shell tank wastes, contaminated soil sites, solid waste burial sites, double-shell tank wastes, encapsulated 137 CsCl and 90 SrF 2 , stored and new solid transuranic (TRU) wastes, and miscellaneous wastes such as contaminated sodium metal. Among the high priority issues to be resolved are characterization of various wastes including early determination of the TRU content of future cladding removal wastes; completion of development of vitrification (Hanford Waste Vitrification Plant) and grout technology; control of subsidence in buried waste sites; and development of criteria and standards including performance assessments of systems proposed for disposal of HSDW. Estimates of the technology costs shown in this report are made on the basis that all identified tasks for all issues associated with the reference disposal plan must be performed. Elimination of, consolidation of, or reduction in the scope of individual tasks will, of course, be reflected in corresponding reduction of overall technology costs

  3. The presentation of the results of Alexander von Humboldt's voyage to Carlos IV

    Directory of Open Access Journals (Sweden)

    Miguel Ángel Puig-Samper

    2016-05-01

    Full Text Available Resumen  Desde nuestras primeras investigaciones sobre la estancia de Alexander von Humboldt en España siempre nos sorprendió la ausencia de una mínima relación posterior del sabio prusiano con la corona española y sus autoridades. Iniciada una nueva investigación, encontramos que efectivamente se produjo el envío de un primer trabajo a Carlos IV desde Roma acompañado de una carta de gratitud por la protección recibida durante su viaje americano y de sumisión a la corona española, que ahora presentamos.   Summary Ever since our first research into Alexander von Humboldt's stay in Spain, the absence of an ensuing relationship between the wise Prussian and the Spanish Crown and Authorities had always surprised us. On starting new research, we found that indeed he sent his first work to Carlos IV from Rome accompanied by a letter of gratitude for the protection he had received during his American trip and submission to the Spanish Crown, which we now present. This first literary fruit of his voyage, which Alexander von Humboldt alluded to in the letter is the first instalment of his work Plantes Équinoxiales, Recueillies au Mexique, dans l’ile de Cuba, dans les provinces de Caracas, de Cumana etc., published in Paris in 1805.   Zusammenfassung Seit unseren ersten Forschungen über den Aufenthalt Alexander von Humboldts in Spanien hat uns das Fehlen einer hieran anschließenden Beziehung des preußischen Wissenschaftlers mit der spanischen Krone und ihren Behörden erstaunt. Im Laufe einer erneuten Aufnahme der Forschung, haben wir nun entdeckt, dass Humboldt in der Tat von Rom aus eine erste Arbeit an Karl IV gesandt hatte, zusammen mit einem Schreiben des Dankes (für den während der amerikanischen Reise erhaltenen Schutz sowie seiner Unterordnung unter die spanische Krone, das wir nun präsentieren. Das erste literarische Ergebnis seiner Reise, auf das Humboldt in diesem Brief verweist, ist der erste Faszikel seines Werkes

  4. [Cognitive rehabilitation in multiple sclerosis: preliminary results and presentation of a new program, PROCOG-SEP].

    Science.gov (United States)

    Brissart, H; Leroy, M; Debouverie, M

    2010-04-01

    Although cognitive disorders are well-known in multiple sclerosis (MS), even in earlier stages of the disease, their management may be overlooked. Our objective was to elaborate and evaluate the efficiency of a remedial program (PROCOG-SEP) designed for MS patients. The evidence-based program proposes exercises to both stimulate preserved functions and develop new abilities compensating for cognitive disabilities. Twenty-four patients with MS participated in 10/2-hour PROCOG-SEP sessions over a 6-month period. A neuropsychologist recorded BCcog-SEP performances before and after the PROCOG-SEP program. In addition, the same neuropsychologist conducted psychoclinical interviews to complete the before and after cognitive evaluations. The statistical analysis used the t-test performed with Excel. Compared with the initial levels, subtests of BCcog-SEP showing improvement after PROCOG-SEP were: verbal memory (SRT), visuospatial memory (10/36), verbal fluency (animal categories) and response to conflicting orders. Also, individual psychological interviews tended to be in favor of a general improvement in quality of life (more social interactions for instance). To our knowledge, the management program we have elaborated is the first designed to improve cognitive deficits in MS. These encouraging results suggest possibilities for improving cognition and thus quality-of-life in MS patients. 2009 Elsevier Masson SAS. All rights reserved.

  5. Urgent recommendation. Interim report

    International Nuclear Information System (INIS)

    Nakano, Masayuki

    2000-01-01

    The Investigation Committee for Critical Accident at Uranium Processing Plant was founded immediately after the accident to investigate the cause of the accident and to establish measures to prevent the similar accident. On September 30, 1999 around 10:35, the Japan's first criticality accident occurred at JCO Co. Ltd. Uranium processing plant (auxiliary conversion plant) located at Tokai-mura Ibaraki-ken. The criticality continued on and off for approximately 20 hours after the first instantaneous criticality. The accident led the recommendation of tentative evacuation and sheltering indoors for residents living in the neighborhood. The serious exposure to neutrons happened to three workers. The dominant effect is dose due to neutrons and gamma rays from the precipitation tank. When the accident took place, three workers dissolved sequentially about 2.4 kg uranium powder with 18.8 % enrichment in the 10-litter bucket with nitric acid. The procedure of homogenization of uranium nitrate was supposed to be controlled using the shape-limited narrow storage column. Actually, however, the thick and large precipitation tank was used. As a result, about 16.6 kg of uranium was fed into the tank, which presumably caused criticality. The first notification by JCO was delayed and the following communication was not smooth. This led to the delay of correct understanding of the situation and made the initial proper response difficult, then followed by insufficient communication between the nation, prefecture, and local authority. Urgent recommendations were made on the following items; (1) Safety measures to be taken at the accident site, (2) health cares for residents and others, (3) Comprehensive safety securing at nuclear operators such as Establishment of the effective audit system, Safety education for employees and Qualification and licensing system, Safety related documents, etc. (4) Reconstruction of the government's safety regulations such as How safety regulation

  6. Analysis of removal of residual decay heat from interim storage facilities by means of the CFD program FLUENT

    International Nuclear Information System (INIS)

    Stratmann, W.; Hages, P.

    2004-01-01

    Within the scope of nuclear licensing procedures of on-site interim storage facilities for dual purpose casks it is necessary, among other things, to provide proof of sufficient removal of the residual decay heat emitted by the casks. The results of the analyses performed for this purpose define e.g. the boundary conditions for further thermal analyses regarding the permissible cask component temperatures or the maximum permissible temperatures of the fuel cladding tubes of the fuel elements stored in the casks. Up to now, for the centralized interim storage facilities in Germany such analyses were performed on the basis of experimental investigations using scaled-down storage geometries. In the engineering phase of the Lingen on-site interim storage facility, proof was furnished for the first time using the CFD (computational fluid dynamics) program FLUENT. The program FLUENT is an internationally recognized and comprehensively verified program for the calculation of flow and heat transport processes. Starting from a brief discussion of modeling and the different boundary conditions of the computation, this contribution presents various results regarding the temperatures of air, cask surfaces and storage facility components, the mass flows through the storage facility and the heat transfer at the cask surface. The interface point to the cask-specific analyses is defined to be the cask surface

  7. {Carbon and oxygen isotope signals from marine ostracod calcite - results from present and past oceans}

    Science.gov (United States)

    Bornemann, A.; Speijer, R. P.

    2009-04-01

    Systematic stable isotope studies on ostracod calcite are generally rare, in particular for marine taxa only the work of DIDIÉ & BAUCH (2002) provides first clues towards an improved understanding of ostracod stable isotope data in paleoceanography. Here we present analyses from recent near surface sediments from the Gulf of Taranto, the Levantine Basin (15 ka, both Mediterranean Sea) and the Paleocene of Tunisia (southern Tethyan margin). Data are compared to those from selected benthic foraminiferal taxa from which the living habitat and the isotopic disequilibria from ambient sea-water are well known. In addition, size fractions of monospecific samples have been studied in order to test whether a size/mass dependent change exists with respect to the isotopic composition of the carapace calcite. Calcification of ostracod carapaces is a very rapid process, which often takes place within a few hours and the obtained signal provides only a snap-shot of the prevailing paleoceanographic conditions. Multiple mono-specific measurements show therefore a much higher variability than benthic foraminifera, but may give a more complete picture of the seasonal changes. Our study confirms the findings of DIDIÉ & BAUCH (2002) and others (for non-marine taxa) that ostracod calcite displays a positive species-specific deviation from the sea-water ^18O composition between 0.5 and 1.5 per mil with an intra-specific variability of less than 0.5 per mil. In contrast ^13C values cover a huge range with an off-set from sea-water of up to -5 per mil and show a high intra-specific variability of up to 2 per mil. Size-fraction data show no systematic change, although a statistically significant positive covariance between ^18O and ^13C has been observed. This covariance consists of a slope similar to a kinetic controlled fractionation as has been described from asymbiotic planktic foraminifera (Globigerina bulloides) and corals (MCCONNAUGHEY, 1989; SPERO & LEA, 1996). This suggests that

  8. Urgent recommendation. Interim report

    Energy Technology Data Exchange (ETDEWEB)

    Nakano, Masayuki [International Affairs and Safeguards Division, Atomic Energy Bureau, Science and Technology Agency, Tokyo (Japan)

    2000-12-01

    The Investigation Committee for Critical Accident at Uranium Processing Plant was founded immediately after the accident to investigate the cause of the accident and to establish measures to prevent the similar accident. On September 30, 1999 around 10:35, the Japan's first criticality accident occurred at JCO Co. Ltd. Uranium processing plant (auxiliary conversion plant) located at Tokai-mura Ibaraki-ken. The criticality continued on and off for approximately 20 hours after the first instantaneous criticality. The accident led the recommendation of tentative evacuation and sheltering indoors for residents living in the neighborhood. The serious exposure to neutrons happened to three workers. The dominant effect is dose due to neutrons and gamma rays from the precipitation tank. When the accident took place, three workers dissolved sequentially about 2.4 kg uranium powder with 18.8 % enrichment in the 10-litter bucket with nitric acid. The procedure of homogenization of uranium nitrate was supposed to be controlled using the shape-limited narrow storage column. Actually, however, the thick and large precipitation tank was used. As a result, about 16.6 kg of uranium was fed into the tank, which presumably caused criticality. The first notification by JCO was delayed and the following communication was not smooth. This led to the delay of correct understanding of the situation and made the initial proper response difficult, then followed by insufficient communication between the nation, prefecture, and local authority. Urgent recommendations were made on the following items; (1) Safety measures to be taken at the accident site, (2) health cares for residents and others, (3) Comprehensive safety securing at nuclear operators such as Establishment of the effective audit system, Safety education for employees and Qualification and licensing system, Safety related documents, etc. (4) Reconstruction of the government's safety regulations such as How safety

  9. Interim results from the CATNON trial (EORTC study 26053-22054) of treatment with concurrent and adjuvant temozolomide for 1p/19q non-co-deleted anaplastic glioma: a phase 3, randomised, open-label intergroup study.

    Science.gov (United States)

    van den Bent, Martin J; Baumert, Brigitta; Erridge, Sara C; Vogelbaum, Michael A; Nowak, Anna K; Sanson, Marc; Brandes, Alba Ariela; Clement, Paul M; Baurain, Jean Francais; Mason, Warren P; Wheeler, Helen; Chinot, Olivier L; Gill, Sanjeev; Griffin, Matthew; Brachman, David G; Taal, Walter; Rudà, Roberta; Weller, Michael; McBain, Catherine; Reijneveld, Jaap; Enting, Roelien H; Weber, Damien C; Lesimple, Thierry; Clenton, Susan; Gijtenbeek, Anja; Pascoe, Sarah; Herrlinger, Ulrich; Hau, Peter; Dhermain, Frederic; van Heuvel, Irene; Stupp, Roger; Aldape, Ken; Jenkins, Robert B; Dubbink, Hendrikus Jan; Dinjens, Winand N M; Wesseling, Pieter; Nuyens, Sarah; Golfinopoulos, Vassilis; Gorlia, Thierry; Wick, Wolfgang; Kros, Johan M

    2017-10-07

    The role of temozolomide chemotherapy in newly diagnosed 1p/19q non-co-deleted anaplastic gliomas, which are associated with lower sensitivity to chemotherapy and worse prognosis than 1p/19q co-deleted tumours, is unclear. We assessed the use of radiotherapy with concurrent and adjuvant temozolomide in adults with non-co-deleted anaplastic gliomas. This was a phase 3, randomised, open-label study with a 2 × 2 factorial design. Eligible patients were aged 18 years or older and had newly diagnosed non-co-deleted anaplastic glioma with WHO performance status scores of 0-2. The randomisation schedule was generated with the electronic EORTC web-based ORTA system. Patients were assigned in equal numbers (1:1:1:1), using the minimisation technique, to receive radiotherapy (59·4 Gy in 33 fractions of 1·8 Gy) alone or with adjuvant temozolomide (12 4-week cycles of 150-200 mg/m 2 temozolomide given on days 1-5); or to receive radiotherapy with concurrent temozolomide 75 mg/m 2 per day, with or without adjuvant temozolomide. The primary endpoint was overall survival adjusted for performance status score, age, 1p loss of heterozygosity, presence of oligodendroglial elements, and MGMT promoter methylation status, analysed by intention to treat. We did a planned interim analysis after 219 (41%) deaths had occurred to test the null hypothesis of no efficacy (threshold for rejection p<0·0084). This trial is registered with ClinicalTrials.gov, number NCT00626990. At the time of the interim analysis, 745 (99%) of the planned 748 patients had been enrolled. The hazard ratio for overall survival with use of adjuvant temozolomide was 0·65 (99·145% CI 0·45-0·93). Overall survival at 5 years was 55·9% (95% CI 47·2-63·8) with and 44·1% (36·3-51·6) without adjuvant temozolomide. Grade 3-4 adverse events were seen in 8-12% of 549 patients assigned temozolomide, and were mainly haematological and reversible. Adjuvant temozolomide chemotherapy was associated with a

  10. Comparison of interim restorations fabricated by CAD/CAM with those fabricated manually.

    Science.gov (United States)

    Rayyan, Mohammad M; Aboushelib, Moustafa; Sayed, Nagwa M; Ibrahim, Ahmed; Jimbo, Ryo

    2015-09-01

    dye penetration in all tested specimens. CAD/CAM interim crowns presented stable physical and mechanical properties and may be used for long-term interim restorations. Copyright © 2015 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

  11. Physical protection of shipments of irradiated reactor fuel; Interim guidance. Regulatory report

    International Nuclear Information System (INIS)

    1980-06-01

    During May, 1979, the U.S. Nuclear Regulatory Commission approved for issuance in effective form new interim regulations for strengthening the protection of spent fuel shipments against sabotage and diversion. The new regulations were issued without benefit of public comment, but comments from the public were solicited after the effective date. Based upon the public comments received, the interim regulations were amended and reissued in effective form as a final interim rule in May, 1980. The present document supersedes a previously issued interim guidance document, NUREG-0561 (June, 1979) which accompanied the original rule. This report has been revised to conform to the new interim regulations on the physical protection of shipments of irradiated reactor fuel which are likely to remain in effect until the completion of an ongoing research program concerning the response of spent fuel to certain forms of sabotage, at which time the regulations may be rescinded, modified or made permanent, as appropriate. This report discusses the amended regulations and provides a basis on which licensees can develop an acceptable interim program for the protection of spent fuel shipments

  12. Interim Evaluation of the Project P.A.T.H.S.: Findings Based on Different Datasets

    Directory of Open Access Journals (Sweden)

    Daniel T. L. Shek

    2012-01-01

    Full Text Available Interim evaluation studies were carried out in order to examine the implementation details of the Tier 1 Program of the Project P.A.T.H.S. (Positive Adolescent Training through Holistic Social Programmes in Hong Kong. Quantitative results of the interim evaluation findings based on eight datasets collected from 2006 to 2009 are reported in this paper. Three hundred and seventy-eight schools were randomly selected to provide information on the implementation details of the program via face-to-face interviews, telephone interviews, and self-completed questionnaires. Results showed that a majority of the workers perceived that the students had positive responses to the program and the program was helpful to the students. In conjunction with other process evaluation findings, the present study suggests that the implementation quality of the Tier 1 Program of the Project P.A.T.H.S. is high. The present study also provides support for the effectiveness of the Tier 1 Program of the Project P.A.T.H.S. in Hong Kong.

  13. Cytogenetical effects of low doses: results obtained by N.N.Luchik and present-day problems

    International Nuclear Information System (INIS)

    Geras'kin, S.A.; Sevan'kaev, A.V.

    1996-01-01

    The analysis of present status of the problem of quantitative assessment of cytogenetic effects low is presented. The importance of works of N.V. Luchik is demonstrated for the development of this field of radiobiology. The results of the author's own experimental and theoretical research on the regularities of induction of cytogenetical damage by low doses of ionising radiation are presented

  14. Plutonium Finishing Plant. Interim plutonium stabilization engineering study

    Energy Technology Data Exchange (ETDEWEB)

    Sevigny, G.J.; Gallucci, R.H.; Garrett, S.M.K.; Geeting, J.G.H.; Goheen, R.S.; Molton, P.M.; Templeton, K.J.; Villegas, A.J. [Pacific Northwest Lab., Richland, WA (United States); Nass, R. [Nuclear Fuel Services, Inc. (United States)

    1995-08-01

    This report provides the results of an engineering study that evaluated the available technologies for stabilizing the plutonium stored at the Plutonium Finishing Plant located at the hanford Site in southeastern Washington. Further processing of the plutonium may be required to prepare the plutonium for interim (<50 years) storage. Specifically this document provides the current plutonium inventory and characterization, the initial screening process, and the process descriptions and flowsheets of the technologies that passed the initial screening. The conclusions and recommendations also are provided. The information contained in this report will be used to assist in the preparation of the environmental impact statement and to help decision makers determine which is the preferred technology to process the plutonium for interim storage.

  15. Plutonium Finishing Plant. Interim plutonium stabilization engineering study

    International Nuclear Information System (INIS)

    Sevigny, G.J.; Gallucci, R.H.; Garrett, S.M.K.; Geeting, J.G.H.; Goheen, R.S.; Molton, P.M.; Templeton, K.J.; Villegas, A.J.; Nass, R.

    1995-08-01

    This report provides the results of an engineering study that evaluated the available technologies for stabilizing the plutonium stored at the Plutonium Finishing Plant located at the hanford Site in southeastern Washington. Further processing of the plutonium may be required to prepare the plutonium for interim (<50 years) storage. Specifically this document provides the current plutonium inventory and characterization, the initial screening process, and the process descriptions and flowsheets of the technologies that passed the initial screening. The conclusions and recommendations also are provided. The information contained in this report will be used to assist in the preparation of the environmental impact statement and to help decision makers determine which is the preferred technology to process the plutonium for interim storage

  16. Lamar Low-Level Jet Program Interim Report

    Energy Technology Data Exchange (ETDEWEB)

    Kelley, N.; Shirazi, M.; Jager, D.; Wilde, S.; Adams, J.; Buhl, M.; Sullivan, P.; Patton, E.

    2004-01-01

    This interim report presents the results to date from the Lamar Low-Level Jet Program (LLLJP) that has been established as joint effort among the U.S. Department of Energy (DOE), the National Wind Technology Center (NWTC) of the National Renewable Energy Laboratory (NREL), and General Electric Wind Energy (GE Wind). The purpose of this project is to develop an understanding of the influence of nocturnal low-level jet streams on the inflow turbulence environment and the documenting of any potential operating impacts on current large wind turbines and the Low Wind Speed Turbine (LWST) designs of the future. A year's record of detailed nocturnal turbulence measurements has been collected from NREL instrumentation installed on the GE Wind 120-m tower in southeastern Colorado and supplemented with mean wind profile data collected using an acoustic wind profiler or SODAR (Sound Detection and Ranging). The analyses of measurements taken as part of a previous program conducted at the NWTC have been used to aid in the interpretation of the results of representative case studies of data collected from the GE Wind tower.

  17. GPS water vapor and its comparison with radiosonde and ERA-Interim data in Algeria

    Science.gov (United States)

    Namaoui, Houaria; Kahlouche, Salem; Belbachir, Ahmed Hafid; Van Malderen, Roeland; Brenot, Hugues; Pottiaux, Eric

    2017-05-01

    Remote sensing of atmospheric water vapor using global positioning system (GPS) data has become an effective tool in meteorology, weather forecasting and climate research. This paper presents the estimation of precipitable water (PW) from GPS observations and meteorological data in Algeria, over three stations located at Algiers, Bechar and Tamanrasset. The objective of this study is to analyze the sensitivity of the GPS PW estimates for the three sites to the weighted mean temperature ( T m), obtained separately from two types of T m- T s regression [one general, and one developed specifically for Algeria ( T s stands for surface temperature)], and calculated directly from ERA-Interim data. The results show that the differences in T m are of the order of 18 K, producing differences of 2.01 mm in the final evaluation of PW. A good agreement is found between GPS-PW and PW calculated from radiosondes, with a small mean difference with Vaisala radiosondes. A comparison between GPS and ERA-Interim shows a large difference (4 mm) in the highlands region. This difference is possibly due to the topography. These first results are encouraging, in particular for meteorological applications in this region, with good hope to extend our dataset analysis to a more complete, nationwide coverage over Algeria.

  18. The experiences from interim spent fuel storage operation with CASTOR 440/84 CASKS in NPP Dukovany

    International Nuclear Information System (INIS)

    Kuba, S.

    1999-01-01

    In this lecture are presented: principles of the CASTOR 440/84 design; design development works; commissioning of interim spent fuel storage facility; international transports of spent fuel utilising CASTOR 440/84 casks

  19. International Workshop on Exotic Hadronic Atoms, Deeply Bound Kaonic Nuclear States and Antihydrogen : Present Results, Future Challenges

    CERN Document Server

    Widmann, E; Curceanu, C; Trento 2006; Trento06

    2006-01-01

    These are the miniproceedings of the workshop "Exotic hadronic atoms, deeply bound kaonic nuclear states and antihydrogen: present results, future challenges," which was held at the European Centre for Theoretical Nuclear Physics and Related Studies (ECT*), Trento (Italy), June 19-24, 2006. The document includes a short presentation of the topics, the list of participants, and a short contribution from each speaker.

  20. The reactive transport benchmark proposed by GdR MoMaS: presentation and first results

    Energy Technology Data Exchange (ETDEWEB)

    Carrayrou, J. [Institut de Mecanique des Fluides et des Solides, UMR ULP-CNRS 7507, 67 - Strasbourg (France); Lagneau, V. [Ecole des Mines de Paris, Centre de Geosciences, 77 - Fontainebleau (France)

    2007-07-01

    We present here the actual context of reactive transport modelling and the major numerical challenges. GdR MoMaS proposes a benchmark on reactive transport. We present this benchmark and some results obtained on it by two reactive transport codes HYTEC and SPECY. (authors)

  1. The reactive transport benchmark proposed by GdR MoMaS: presentation and first results

    International Nuclear Information System (INIS)

    Carrayrou, J.; Lagneau, V.

    2007-01-01

    We present here the actual context of reactive transport modelling and the major numerical challenges. GdR MoMaS proposes a benchmark on reactive transport. We present this benchmark and some results obtained on it by two reactive transport codes HYTEC and SPECY. (authors)

  2. What is Needed in the EU's 2030 Climate and Energy Framework. Interim Discussion Paper and Results from a Research Project Led by IDDRI and Climate Strategies

    International Nuclear Information System (INIS)

    Sartor, Oliver; Spencer, Thomas IDDRI; Colombier, Michel; Bart, Istvan; Cochran, Ian; Neuhoff, Karsten; Szpor, Aleksander; Tuerk, Andreas; Wyns, Tomas

    2014-01-01

    The EU 2030 Climate and Energy Framework presents a number of technical challenges whose solution will be essential to its effectiveness. These include: the question of the role and reform of the ETS, the approach to decarbonization of non-ETS sectors, and the mechanisms that exist for governing the package of policies at EU and Member State level. This discussion paper presents preliminary results from an analysis of these challenges, as well as proposals that could be included in the package of post- 2020 climate policies. (authors)

  3. Project management plan for the 105-C Reactor interim safe storage project. Revision 1

    International Nuclear Information System (INIS)

    Miller, R.L.

    1997-01-01

    In 1942, the Hanford Site was commissioned by the US Government to produce plutonium. Between 1942 and 1955, eight water-cooled, graphite-moderated reactors were constructed along the Columbia River at the Hanford Site to support the production of plutonium. The reactors were deactivated from 1964 to 1971 and declared surplus. The Surplus Production Reactor Decommissioning Project (BHI 1994b) will decommission these reactors and has selected the 105-C Reactor to be used as a demonstration project for interim safe storage at the present location and final disposition of the entire reactor core in the 200 West Area. This project will result in lower costs, accelerated schedules, reduced worker exposure, and provide direct benefit to the US Department of Energy for decommissioning projects complex wide. This project sets forth plans, organizational responsibilities, control systems, and procedures to manage the execution of the Project Management Plan for the 105-C Reactor Interim Safe Storage Project (Project Management Plan) activities to meet programmatic requirements within authorized funding and approved schedules. The Project Management Plan is organized following the guidelines provided by US Department of Energy Order 4700.1, Project Management System and the Richland Environmental Restoration Project Plan (DOE-RL 1992b)

  4. Interim Basis for PCB Sampling and Analyses

    International Nuclear Information System (INIS)

    BANNING, D.L.

    2001-01-01

    This document was developed as an interim basis for sampling and analysis of polychlorinated biphenyls (PCBs) and will be used until a formal data quality objective (DQO) document is prepared and approved. On August 31, 2000, the Framework Agreement for Management of Polychlorinated Biphenyls (PCBs) in Hanford Tank Waste was signed by the US. Department of Energy (DOE), the Environmental Protection Agency (EPA), and the Washington State Department of Ecology (Ecology) (Ecology et al. 2000). This agreement outlines the management of double shell tank (DST) waste as Toxic Substance Control Act (TSCA) PCB remediation waste based on a risk-based disposal approval option per Title 40 of the Code of Federal Regulations 761.61 (c). The agreement calls for ''Quantification of PCBs in DSTs, single shell tanks (SSTs), and incoming waste to ensure that the vitrification plant and other ancillary facilities PCB waste acceptance limits and the requirements of the anticipated risk-based disposal approval are met.'' Waste samples will be analyzed for PCBs to satisfy this requirement. This document describes the DQO process undertaken to assure appropriate data will be collected to support management of PCBs and is presented in a DQO format. The DQO process was implemented in accordance with the U.S. Environmental Protection Agency EPA QAlG4, Guidance for the Data Quality Objectives Process (EPA 1994) and the Data Quality Objectives for Sampling and Analyses, HNF-IP-0842/Rev.1 A, Vol. IV, Section 4.16 (Banning 1999)

  5. The EMEFS model evaluation. An interim report

    Energy Technology Data Exchange (ETDEWEB)

    Barchet, W.R. [Pacific Northwest Lab., Richland, WA (United States); Dennis, R.L. [Environmental Protection Agency, Research Triangle Park, NC (United States); Seilkop, S.K. [Analytical Sciences, Inc., Durham, NC (United States); Banic, C.M.; Davies, D.; Hoff, R.M.; Macdonald, A.M.; Mickle, R.E.; Padro, J.; Puckett, K. [Atmospheric Environment Service, Downsview, ON (Canada); Byun, D.; McHenry, J.N. [Computer Sciences Corp., Research Triangle Park, NC (United States); Karamchandani, P.; Venkatram, A. [ENSR Consulting and Engineering, Camarillo, CA (United States); Fung, C.; Misra, P.K. [Ontario Ministry of the Environment, Toronto, ON (Canada); Hansen, D.A. [Electric Power Research Inst., Palo Alto, CA (United States); Chang, J.S. [State Univ. of New York, Albany, NY (United States). Atmospheric Sciences Research Center

    1991-12-01

    The binational Eulerian Model Evaluation Field Study (EMEFS) consisted of several coordinated data gathering and model evaluation activities. In the EMEFS, data were collected by five air and precipitation monitoring networks between June 1988 and June 1990. Model evaluation is continuing. This interim report summarizes the progress made in the evaluation of the Regional Acid Deposition Model (RADM) and the Acid Deposition and Oxidant Model (ADOM) through the December 1990 completion of a State of Science and Technology report on model evaluation for the National Acid Precipitation Assessment Program (NAPAP). Because various assessment applications of RADM had to be evaluated for NAPAP, the report emphasizes the RADM component of the evaluation. A protocol for the evaluation was developed by the model evaluation team and defined the observed and predicted values to be used and the methods by which the observed and predicted values were to be compared. Scatter plots and time series of predicted and observed values were used to present the comparisons graphically. Difference statistics and correlations were used to quantify model performance. 64 refs., 34 figs., 6 tabs.

  6. Aquifer Sampling Tube Results for Fiscal Year 2003

    Energy Technology Data Exchange (ETDEWEB)

    Hartman, Mary J.; Peterson, Robert E.

    2003-10-27

    This report presents and discusses results of the fiscal year 2003 sampling event associated with aquifer tubes along the Columbia River in the northern Hanford Site. Aquifer tube data help define the extent of groundwater contamination near the river, determine vertical variations in contamination, monitor the performance of interim remedial actions near the river, and support impact studies.

  7. Thermal-Mechanical Stress Analysis of PWR Pressure Vessel and Nozzles under Grid Load-Following Mode: Interim Report on the Effect of Cyclic Hardening Material Properties and Pre-existing Cracks on Stress Analysis Results

    Energy Technology Data Exchange (ETDEWEB)

    Mohanty, Subhasish [Argonne National Lab. (ANL), Argonne, IL (United States); Soppet, William [Argonne National Lab. (ANL), Argonne, IL (United States); Majumdar, Saurin [Argonne National Lab. (ANL), Argonne, IL (United States); Natesan, Ken [Argonne National Lab. (ANL), Argonne, IL (United States)

    2016-03-15

    This report provides an update on an assessment of environmentally assisted fatigue for light water reactor components under extended service conditions. This report is a deliverable under the work package for environmentally assisted fatigue as part of DOE’s Light Water Reactor Sustainability Program. In a previous report (September 2015), we presented tensile and fatigue test data and related hardening material properties for 508 low-alloys steel base metal and other reactor metals. In this report, we present thermal-mechanical stress analysis of the reactor pressure vessel and its hot-leg and cold-leg nozzles based on estimated material properties. We also present results from thermal and thermal-mechanical stress analysis under reactor heat-up, cool-down, and grid load-following conditions. Analysis results are given with and without the presence of preexisting cracks in the reactor nozzles (axial or circumferential crack). In addition, results from validation stress analysis based on tensile and fatigue experiments are reported.

  8. Early interim 18F-FDG PET in Hodgkin's lymphoma: evaluation on 304 patients

    International Nuclear Information System (INIS)

    Zinzani, Pier Luigi; Stefoni, Vittorio; Broccoli, Alessandro; Argnani, Lisa; Baccarani, Michele; Rigacci, Luigi; Puccini, Benedetta; Castagnoli, Antonio; Vaggelli, Luca; Zanoni, Lucia; Fanti, Stefano

    2012-01-01

    The use of early (interim) PET restaging during first-line therapy of Hodgkin's lymphoma (HL) in clinical practice has considerably increased because of its ability to provide early recognition of treatment failure allowing patients to be transferred to more intensive treatment regimens. Between June 1997 and June 2009, 304 patients with newly diagnosed HL (147 early stage and 157 advanced stage) were treated with the ABVD regimen at two Italian institutions. Patients underwent PET staging and restaging at baseline, after two cycles of therapy and at the end of the treatment. Of the 304 patients, 53 showed a positive interim PET scan and of these only 13 (24.5%) achieved continuous complete remission (CCR), whereas 251 patients showed a negative PET scan and of these 231 (92%) achieved CCR. Comparison between interim PET-positive and interim PET-negative patients indicated a significant association between PET findings and 9-year progression-free survival and 9-year overall survival, with a median follow-up of 31 months. Among the early-stage patients, 19 had a positive interim PET scan and only 4 (21%) achieved CCR; among the 128 patients with a negative interim PET scan, 122 (97.6%) achieved CCR. Among the advanced-stage patients, 34 showed a persistently positive PET scan with only 9 (26.4%) achieving CCR, whereas 123 showed a negative interim PET scan with 109 (88.6%) achieving CCR. Our results demonstrate the role of an early PET scan as a significant step forward in the management of patients with early-stage or advanced-stage HL. (orig.)

  9. [The history of the Kaiser Wilhelm Society during the Third Reich. Interim reports of the president's commission of the Max Planck Society].

    Science.gov (United States)

    Weber, M M

    2002-11-01

    In 1997 the Max Planck Society set up a presidential commission to do research on the historical development of its precursor organization, the Kaiser Wilhelm Society (KWG), during the Third Reich. This paper presents some of the important results given in the interim reports of this commission that are relevant to psychiatry. It focuses on brain research, anthropology, psychiatric genetics, and the role of the well-known biochemist Adolf Butenandt. In general, the interim reports reflect the numerous links between the biomedical research of the KWG and the institutions of the National Socialist (Nazi) state. However, they do not yet allow a final historical assessment as to the complex situation of this field of research during National Socialism.

  10. Design review report FFTF interim storage cask

    International Nuclear Information System (INIS)

    Scott, P.L.

    1995-01-01

    Final Design Review Report for the FFTF Interim Storage Cask. The Interim Storage Cask (ISC) will be used for long term above ground dry storage of FFTF irradiated fuel in Core Component Containers (CCC)s. The CCC has been designed and will house assemblies that have been sodium washed in the IEM Cell. The Solid Waste Cask (SWC) will transfer a full CCC from the IEM Cell to the RSB Cask Loading Station where the ISC will be located to receive it. Once the loaded ISC has been sealed at the RSB Cask Loading Station, it will be transferred by facility crane to the DSWC Transporter. After the ISC has been transferred to the Interim Storage Area (ISA), which is yet to be designed, a mobile crane will be used to place the ISC in its final storage location

  11. Interim Administrators in Higher Education: A National Study

    Science.gov (United States)

    Huff, Marie Thielke; Neubrander, Judy

    2015-01-01

    The focus of this paper is on the roles and experiences of interim administrators in higher education. A survey was given to current and recent interim administrators in four-year public universities and colleges across the United States. The goals were to identify the advantages and disadvantages of using and serving as interims, and to solicit…

  12. Transuranic storage and assay facility interim safety basis

    Energy Technology Data Exchange (ETDEWEB)

    Porten, D.R., Fluor Daniel Hanford

    1997-02-12

    The Transuranic Waste Storage and Assay Facility (TRUSAF) Interim Safety Basis document provides the authorization basis for the interim operation and restriction on interim operations for the TRUSAF. The TRUSAF ISB demonstrates that the TRUSAF can be operated safely, protecting the workers, the public, and the environment. The previous safety analysis document TRUSAF Hazards Identification and Evaluation (WHC 1987) is superseded by this document.

  13. 13 CFR 120.890 - Source of interim financing.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Source of interim financing. 120.890 Section 120.890 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION BUSINESS LOANS Development Company Loan Program (504) Interim Financing § 120.890 Source of interim financing. A Project may...

  14. An Approach for Evaluating the Technical Quality of Interim Assessments

    Science.gov (United States)

    Li, Ying; Marion, Scott; Perie, Marianne; Gong, Brian

    2010-01-01

    Increasing numbers of schools and districts have expressed interest in interim assessment systems to prepare for summative assessments and to improve teaching and learning. However, with so many commercial interim assessments available, schools and districts are struggling to determine which interim assessment is most appropriate to their needs.…

  15. Interim financial reporting in function of proper decision making

    Directory of Open Access Journals (Sweden)

    Kaćanski Slobodan

    2014-01-01

    Full Text Available This paper analyses the attributes of interim financial reporting, as well as performs overview and interpretation of International Accounting Standard 34 which deals with this issue. The paper emphasizes risk and effects of interim financial statements implementation in decision making process. Time and cost limitations significantly influence the level of reliability on interim reports since those reports were not audited.

  16. Interim financial reporting in function of proper decision making

    OpenAIRE

    Kaćanski Slobodan; Tomašević Stevan; Vlaović-Begović Sanja

    2014-01-01

    This paper analyses the attributes of interim financial reporting, as well as performs overview and interpretation of International Accounting Standard 34 which deals with this issue. The paper emphasizes risk and effects of interim financial statements implementation in decision making process. Time and cost limitations significantly influence the level of reliability on interim reports since those reports were not audited.

  17. The WFIRST Interim Design Reference Mission: Capabilities, Constraints, and Open Questions

    Science.gov (United States)

    Kruk, Jeffrey W.

    2012-01-01

    The Project Office and Science Definition Team for the Wide-Field Infrared Survey Telescope (WFIRST) are in the midst of a pre-Phase A study to establish a Design Reference Mission (DRM). An Interim report was released in June 2011, with a final report due later in 2012. The predicted performance of the Interim DRM Observatory will be described, including optical quality, observing efficiency, and sensitivity for representative observing scenarios. Observing constraints and other limitations on performance will also be presented, with an emphasis on potential Guest Observer programs. Finally, a brief status update will be provided on open trade studies of interest to the scientific community. The final DRM may differ from the Interim DRM presented here. However, the underlying requirements of the scientific programs are not expected to change, hence the capabilities of the IDRM are likely to be maintained even if the implementation changes in significant ways.

  18. Atmospheric Effects of Subsonic Aircraft: Interim Assessment Report of the Advanced Subsonic Technology Program

    Science.gov (United States)

    Friedl, Randall R. (Editor)

    1997-01-01

    This first interim assessment of the subsonic assessment (SASS) project attempts to summarize concisely the status of our knowledge concerning the impacts of present and future subsonic aircraft fleets. It also highlights the major areas of scientific uncertainty, through review of existing data bases and model-based sensitivity studies. In view of the need for substantial improvements in both model formulations and experimental databases, this interim assessment cannot provide confident numerical predictions of aviation impacts. However, a number of quantitative estimates are presented, which provide some guidance to policy makers.

  19. 216-T-4 interim stabilization final report

    International Nuclear Information System (INIS)

    Smith, D.L.

    1996-01-01

    This report provides a general description of the activities performed for the interim stabilization of the 216-T-4-1 ditch, 216-T-4-2 ditch, and 216-T-4-2 pond. Interim stabilization was required to reduce the amount of surface-contaminated acres and to minimize the migration of radioactive contamination. Work associated with the 216-T4-1 ditch and 216-T-4-2 pond was performed by the Radiation Area Remedial Action (RARA) Project. Work associated with the 216-T-4-2 ditch was done concurrently but was funded by Westinghouse Hanford Company (WHC) Tank Waste Remediation Systems (TWRS)

  20. Commentary: Interim leadership of academic departments at U.S. medical schools.

    Science.gov (United States)

    Grigsby, R Kevin; Aber, Robert C; Quillen, David A

    2009-10-01

    Medical schools and teaching hospitals are experiencing more frequent turnover of department chairs. Loss of a department chair creates instability in the department and may have a negative effect on the organization at large. Interim leadership of academic departments is common, and interim chairs are expected to immediately demonstrate skills and leadership abilities. However, little is known about how persons are prepared to assume the interim chair role. Newer competencies for effective leadership include an understanding of the business of medicine, interpersonal and communication skills, the ability to deal with conflict and solve adaptive challenges, and the ability to build and work on teams. Medical schools and teaching hospitals need assistance to meet the unique training and support needs of persons serving as interim leaders. For example, the Association of American Medical Colleges and individual chair societies can develop programs to allow current chairs to reflect on their present positions and plan for the future. Formal leadership training, mentorship opportunities, and conscientious succession planning are good first steps in preparing to meet the needs of academic departments during transitions in leadership. Also, interim leadership experience may be useful as a means for "opening the door" to underrepresented persons, including women, and increasing the diversity of the leadership team.

  1. Quarrels on the meaning of youth: what the interim measure ends

    Directory of Open Access Journals (Sweden)

    Raquel Alvarenga Sena Venera

    2016-10-01

    Full Text Available http://dx.doi.org/10.5007/1984-8420.2016v17n2p120 This article is a reflection from the context of the publication of the Measure no. 746, from 2016, that became Bill no. 13,415, in 2017, but also, and mainly, based on the group of former analyses about youth meanings in disputes in the language game on the curriculum policies regarding high school. These analyses were made in a net of investigations, with different epistemological paths, with very close intentions and results. The present reflection highlights one of these analyses, which, through discourse analysis together with Orlandi (2011, analyzed  the Programa Ensino Médio Inovador (ProEMI; Innovative High School Program. These analyses provide visibility to the youth meanings in disputes, and the present reflection understands the interim measure as an attempt to end the dispute.

  2. Fit of interim crowns fabricated using photopolymer-jetting 3D printing.

    Science.gov (United States)

    Mai, Hang-Nga; Lee, Kyu-Bok; Lee, Du-Hyeong

    2017-08-01

    The fit of interim crowns fabricated using 3-dimensional (3D) printing is unknown. The purpose of this in vitro study was to evaluate the fit of interim crowns fabricated using photopolymer-jetting 3D printing and to compare it with that of milling and compression molding methods. Twelve study models were fabricated by making an impression of a metal master model of the mandibular first molar. On each study model, interim crowns (N=36) were fabricated using compression molding (molding group, n=12), milling (milling group, n=12), and 3D polymer-jetting methods. The crowns were prepared as follows: molding group, overimpression technique; milling group, a 5-axis dental milling machine; and polymer-jetting group using a 3D printer. The fit of interim crowns was evaluated in the proximal, marginal, internal axial, and internal occlusal regions by using the image-superimposition and silicone-replica techniques. The Mann-Whitney U test and Kruskal-Wallis tests were used to compare the results among groups (α=.05). Compared with the molding group, the milling and polymer-jetting groups showed more accurate results in the proximal and marginal regions (Ppolymer-jetting group was the most accurate, and compared with the other groups, the milling group showed larger internal discrepancies (PPolymer-jet 3D printing significantly enhanced the fit of interim crowns, particularly in the occlusal region. Copyright © 2016 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

  3. [Effect of the presentation of results from clinical trials on the intention to prescribing: relativity of the relative risk].

    Science.gov (United States)

    Meneu Ricardo, R; Peiró, S; Márquez Calderón, S

    1998-04-30

    To determine if the methods of reporting results of clinical trials affects the physician views on prescribing. Analysis of responses, from a convenience sample of primary care physicians, of one teaching exercise on prescribing intention which showed 5 different methods of reporting results: relative risk reduction (RRR), absolute risk reduction, the percent of event free patients, the number needed to treat (NNT) and RRR and mortality. Curses of clinical management in Valencia and Barcelona. The willingness to prescribe was significantly influenced by the way in which data were presented, being major when they were showed as RRR and minor when mortality was added. The method of reporting trial results has an important influence on the prescribing intention. The reporting of clinical trial results, and their abstracts or citations, should be include the NNT and negative results, for avoiding a subjective bias of treatment effect magnification.

  4. Interim report on the TMI-2 purification filter examination

    International Nuclear Information System (INIS)

    Mason, R.E.; Hobbins, R.R.; Cook, B.A.; MacDonald, P.E.

    1983-02-01

    Filters from the purification/makeup system of the Three Mile Island Unit 2 Reactor were examined after the March 28, 1979, accident to determine the character of the debris transported to the filters. The general condition of the filters is presented. Material was removed from the filters and examined. The elemental and radionuclide makeup of the debris is discussed. Distribution of particle size and shape is presentd for some of the material examined. This is an interim report. When the investigation is completed, another report summarizing all of the data will be issued

  5. Effectiveness of interim remedial actions at a radioactive waste facility

    International Nuclear Information System (INIS)

    Devgun, J.S.; Beskid, N.J.; Peterson, J.M.; Seay, W.M.; McNamee, E.

    1989-01-01

    Over the past eight years, several interim remedial actions have been taken at the Niagara Falls Storage Site (NFSS), primarily to reduce radon and gamma radiation exposures and to consolidate radioactive waste into a waste containment facility. Interim remedial actions have included capping of vents, sealing of pipes, relocation of the perimeter fence (to limit radon risk), transfer and consolidation of waste, upgrading of storage buildings, construction of a clay cutoff wall (to limit the potential groundwater transport of contaminants), treatment and release of contaminated water, interim use of a synthetic liner, and emplacement of an interim clay cap. An interim waste containment facility was completed in 1986. 6 refs., 3 figs

  6. Long-term interim storage concepts with conditioning strategies ensuring compatibility with subsequent disposal or reprocessing

    International Nuclear Information System (INIS)

    Moitrier, C.; Tirel, I.; Villard, C.

    2000-01-01

    The objective of the CEA studies carried out under research topic 3 (long-term interim storage) of the 1991 French radioactive waste management law is to demonstrate the industrial feasibility of a comprehensive, flexible interim storage facility by thoroughly evaluating and comparing all the basic components of various interim storage concepts. In this context, the CEA is considering reference solutions or concepts based on three primary components (the package, the interim storage facility and the site) suitable for determining the specifications of a very long-term solution. Some aspects are examined in greater detail, such as the implementation of long-term technologies, conditioning processes ensuring the absence of water and contamination in the facility, or allowance for radioactive decay of the packages. The results obtained are continually compiled in reports substantiating the design options. These studies should also lead to an overall economic assessment in terms of the capital and operating cost requirements, thereby providing an additional basis for selecting the design options. The comparison with existing industrial facilities highlights the technical and economic progress represented by the new generation of interim storage units. (authors)

  7. Present Status And First Results of the Final Focus Beam Line at the KEK Accelerator Test Facility

    Energy Technology Data Exchange (ETDEWEB)

    Bambade, P.; /Orsay /KEK, Tsukuba; Alabau Pons, M.; /Valencia U., IFIC; Amann, J.; /SLAC; Angal-Kalinin, D.; /Daresbury; Apsimon, R.; /Oxford U., JAI; Araki, S.; Aryshev, A.; /KEK, Tsukuba; Bai, S.; /Beijing, Inst. High Energy Phys.; Bellomo, P.; /SLAC; Bett, D.; /Oxford U., JAI; Blair, G.; /Royal Holloway, U. of London; Bolzon, B.; /Savoie U.; Boogert, S.; Boorman, G.; /Royal Holloway, U. of London; Burrows, P.N.; Christian, G.; Coe, P.; Constance, B.; /Oxford U., JAI; Delahaye, Jean-Pierre; /CERN; Deacon, L.; /Royal Holloway, U. of London; Elsen, E.; /DESY /Valencia U., IFIC /KEK, Tsukuba /Beijing, Inst. High Energy Phys. /Savoie U. /Fermilab /Ecole Polytechnique /KEK, Tsukuba /Kyungpook Natl. U. /KEK, Tsukuba /Pohang Accelerator Lab. /Kyoto U., Inst. Chem. Res. /Savoie U. /Daresbury /Tokyo U. /Royal Holloway, U. of London /Kyungpook Natl. U. /Pohang Accelerator Lab. /Tokyo U. /KEK, Tsukuba /SLAC /University Coll. London /KEK, Tsukuba /SLAC /Royal Holloway, U. of London /KEK, Tsukuba /Tokyo U. /SLAC /Tohoku U. /KEK, Tsukuba /Tokyo U. /Pohang Accelerator Lab. /Brookhaven /SLAC /Oxford U., JAI /SLAC /Orsay /KEK, Tsukuba /Oxford U., JAI /Orsay /Fermilab /Tohoku U. /Manchester U. /CERN /SLAC /Tokyo U. /KEK, Tsukuba /Oxford U., JAI /Hiroshima U. /KEK, Tsukuba /CERN /KEK, Tsukuba /Oxford U., JAI /Ecole Polytechnique /SLAC /Oxford U., JAI /Fermilab /SLAC /Liverpool U. /SLAC /Tokyo U. /SLAC /Tokyo U. /KEK, Tsukuba /SLAC /CERN

    2011-11-11

    ATF2 is a final-focus test beam line which aims to focus the low emittance beam from the ATF damping ring to a vertical size of about 37 nm and to demonstrate nanometer level beam stability. Several advanced beam diagnostics and feedback tools are used. In December 2008, construction and installation were completed and beam commissioning started, supported by an international team of Asian, European, and U.S. scientists. The present status and first results are described.

  8. Interim Cosmetic Results and Toxicity Using 3D Conformal External Beam Radiotherapy to Deliver Accelerated Partial Breast Irradiation in Patients With Early-Stage Breast Cancer Treated With Breast-Conserving Therapy

    International Nuclear Information System (INIS)

    Vicini, Frank A.; Chen, Peter; Wallace, Michelle; Mitchell, Christina; Hasan, Yasmin; Grills, Inga; Kestin, Larry; Schell, Scott; Goldstein, Neal S.; Kunzman, Jonathan; Gilbert, Sam; Martinez, Alvaro

    2007-01-01

    Purpose: We present our ongoing clinical experience utilizing three-dimensional (3D)-conformal radiation therapy (3D-CRT) to deliver accelerated partial breast irradiation (APBI) in patients with early-stage breast cancer treated with breast-conserving therapy. Methods and Materials: Ninety-one consecutive patients were treated with APBI using our previously reported 3D-CRT technique. The clinical target volume consisted of the lumpectomy cavity plus a 10- to 15 -mm margin. The prescribed dose was 34 or 38.5 Gy in 10 fractions given over 5 consecutive days. The median follow-up was 24 months. Twelve patients have been followed for ≥4 years, 20 for ≥3.5 years, 29 for >3.0 years, 33 for ≥2.5 years, and 46 for ≥2.0 years. Results: No local recurrences developed. Cosmetic results were rated as good/excellent in 100% of evaluable patients at ≥ 6 months (n = 47), 93% at 1 year (n = 43), 91% at 2 years (n = 21), and in 90% at ≥3 years (n = 10). Erythema, hyperpigmentation, breast edema, breast pain, telangiectasias, fibrosis, and fat necrosis were evaluated at 6, 24, and 36 months after treatment. All factors stabilized by 3 years posttreatment with grade I or II rates of 0%, 0%, 0%, 0%, 9%, 18%, and 9%, respectively. Only 2 patients (3%) developed grade III toxicity (breast pain), which resolved with time. Conclusions: Delivery of APBI with 3D-CRT resulted in minimal chronic (≥6 months) toxicity to date with good/excellent cosmetic results. Additional follow-up is needed to assess the long-term efficacy of this form of APBI

  9. 76 FR 58790 - Notice of Interim Approval

    Science.gov (United States)

    2011-09-22

    ... customers, and the O&M Committee to ensure that operation and maintenance is properly funded and charged.... Southeastern Power Administration (Southeastern) is including three rate alternatives. All of the rate alternatives have a revenue requirement of $59,600,000. Rate Scenario 1--Interim Operating Plan The final...

  10. 45 CFR 86.71 - Interim procedures.

    Science.gov (United States)

    2010-10-01

    ... SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Procedures [Interim... Music classes, [43]; 86.34(f) Physical education, [43, 56, 58]; Sex education, [43, 57]; 86.34(e.... 901, 902, Education Amendments of 1972, 86 Stat. 373, 374; 20 U.S.C. 1681, 1682) Pt. 86, Index Subject...

  11. ITER interim design report package documents

    International Nuclear Information System (INIS)

    1996-01-01

    This publication contains the Excerpt from the ITER Council (IC-8), the ITER Interim Design Report, Cost Review and Safety Analysis, ITER Site Requirements and ITER Site Design Assumptions and the Excerpt from the ITER Council (IC-9). 8 figs, 2 tabs

  12. Disposal facility data for the interim performance

    International Nuclear Information System (INIS)

    Eiholzer, C.R.

    1995-01-01

    The purpose of this report is to identify and provide information on the waste package and disposal facility concepts to be used for the low-level waste tank interim performance assessment. Current concepts for the low-level waste form, canister, and the disposal facility will be used for the interim performance assessment. The concept for the waste form consists of vitrified glass cullet in a sulfur polymer cement matrix material. The waste form will be contained in a 2 x 2 x 8 meter carbon steel container. Two disposal facility concepts will be used for the interim performance assessment. These facility concepts are based on a preliminary disposal facility concept developed for estimating costs for a disposal options configuration study. These disposal concepts are based on vault type structures. None of the concepts given in this report have been approved by a Tank Waste Remediation Systems (TWRS) decision board. These concepts will only be used in th interim performance assessment. Future performance assessments will be based on approved designs

  13. 40 CFR 180.319 - Interim tolerances.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Interim tolerances. 180.319 Section 180.319 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS... Raw agricultural commodity Coordination product of zinc ion and maneb Fungicide 1.0 (Calculated as...

  14. Interim Prosthesis Options for Dental Implants.

    Science.gov (United States)

    Siadat, Hakimeh; Alikhasi, Marzieh; Beyabanaki, Elaheh

    2017-06-01

    Dental implants have become a popular treatment modality for replacing missing teeth. In this regard, the importance of restoring patients with function during the implant healing period has grown in recent decades. Esthetic concerns, especially in the anterior region of the maxilla, should also be considered until the definitive restoration is delivered. Another indication for such restorations is maintenance of the space required for esthetic and functional definitive restorations in cases where the implant site is surrounded by natural teeth. Numerous articles have described different types of interim prostheses and their fabrication techniques. This article aims to briefly discuss all types of implant-related interim prostheses by different classification including provisional timing (before implant placement, after implant placement in unloading and loading periods), materials, and techniques used for making the restorations, the type of interim prosthesis retention, and definitive restoration. Furthermore, the abutment torque for such restorations and methods for transferring the soft tissue from interim to definitive prostheses are addressed. © 2015 by the American College of Prosthodontists.

  15. NEXT GENERATION MELTER OPTIONEERING STUDY - INTERIM REPORT

    Energy Technology Data Exchange (ETDEWEB)

    GRAY MF; CALMUS RB; RAMSEY G; LOMAX J; ALLEN H

    2010-10-19

    The next generation melter (NOM) development program includes a down selection process to aid in determining the recommended vitrification technology to implement into the WTP at the first melter change-out which is scheduled for 2025. This optioneering study presents a structured value engineering process to establish and assess evaluation criteria that will be incorporated into the down selection process. This process establishes an evaluation framework that will be used progressively throughout the NGM program, and as such this interim report will be updated on a regular basis. The workshop objectives were achieved. In particular: (1) Consensus was reached with stakeholders and technology providers represented at the workshop regarding the need for a decision making process and the application of the D{sub 2}0 process to NGM option evaluation. (2) A framework was established for applying the decision making process to technology development and evaluation between 2010 and 2013. (3) The criteria for the initial evaluation in 2011 were refined and agreed with stakeholders and technology providers. (4) The technology providers have the guidance required to produce data/information to support the next phase of the evaluation process. In some cases it may be necessary to reflect the data/information requirements and overall approach to the evaluation of technology options against specific criteria within updated Statements of Work for 2010-2011. Access to the WTP engineering data has been identified as being very important for option development and evaluation due to the interface issues for the NGM and surrounding plant. WRPS efforts are ongoing to establish precisely data that is required and how to resolve this Issue. It is intended to apply a similarly structured decision making process to the development and evaluation of LAW NGM options.

  16. Interim report of the task force on energy policy

    International Nuclear Information System (INIS)

    2001-01-01

    A Task Force was established by the Premier of British Columbia in August 2001 to draft an energy policy framework for the province. Based on best practices worldwide, and keeping in mind the specific energy needs of British Columbia, this framework aims at fostering energy development in British Columbia, in accordance with exemplary environmental practices. This interim report comprises the preliminary findings of the Task Force, and public input is sought before the final report is finalized and presented to government. The energy sector of British Columbia comprises hydroelectric power, oil, gas and coal resources. In addition, green energy and alternative energy technologies are being developed, such as wind, solar, and wave power, and hydrogen fuel cells. Industry and individual consumers are well served by the highly developed transmission and distribution systems for energy. Several strategic directions were identified by the Task Force for inclusion in the energy policy of British Columbia, to meet its full potential. They are: growth to ensure safe, reliable energy and take advantage of economic opportunities; diversification; competitiveness; industry restructuring and expansion; environmental imperative; government leadership; and community and First Nations' involvement. Some changes are also required for the continuing success of the energy sector in British Columbia: a move to fully competitive markets in the electricity system, the development of natural gas storage capacity in the Lower Mainland, additional considerations for coal use, and the development of alternative energy sources. It is expected that private capital and more energy supply will result from a fully competitive energy market, which in turn would lower energy costs. Jobs and income would increase as a result of the growth in the sector. Diversification makes good economic and environmental sense. tabs., figs

  17. Cost estimation of interim dry storage for Atucha I NPP

    International Nuclear Information System (INIS)

    Bergallo, Juan E.; Fuenzalida Troyano, Carlos S.

    2007-01-01

    A joint effort between NASA and CNEA has been performed in order to evaluate and fix the strategy of interim spent fuel storage for Atucha I nuclear power plant. In this work the cost estimation on the proposed system was performed in order to fix the parameter and design criteria for the next engineering step. The main results achieved show that both alternatives are all in the same range of costs per unit of mass to be stored, the impact on electricity cost is less than 1 US mills/KWh and the scaling factor achieved is 0.85. (author) [es

  18. Second interim assessment of the Canadian concept for nuclear fuel waste disposal. Volume 4

    International Nuclear Information System (INIS)

    Wuschke, D.M.; Gillespie, P.A.; Mehta, K.K.; Henrich, W.F.; LeNeveu, D.M.; Guvanasen, V.M.; Sherman, G.R.; Donahue, D.C.; Goodwin, B.W.; Andres, T.H.

    1985-12-01

    The nuclear fuel waste disposal concept chosen for development and assessment in Canada involves the isolation of corrosion-resistant containers of waste in a vault located deep in plutonic rock. As the concept and the assessment tools are developed, periodic assessments are performed to permit evaluation of the methodology and provide feedback to those developing the concept. The ultimate goal of these assessments is to predict what impact the disposal system would have on man and the environment if the concept were implemented. The second such assessment was performed in 1984 and is documented in the Second Interim Assessment of the Canadian Concept for Nuclear Fuel Waste Disposal - Volumes 1-4. This volume, entitled Post-Closure Assessment, describes the methods, models and data used to perform the second post-closure assessment. The results are presented and their significance is discussed. Conclusions and planned improvements are listed. 72 refs

  19. Dry oxidation behaviour of metallic containers during long term interim storages

    International Nuclear Information System (INIS)

    Desgranges, C.; Terlain, A.; Bertrand, N.; Gauvain, D.

    2004-01-01

    Low-alloyed steels or carbon steels are considered candidate materials for the fabrication of some nuclear waste package containers for long term interim storage. The containers are required to remain retrievable for centuries. One factor limiting their performance on this time scale is corrosion. The estimation of the metal thickness lost by dry oxidation over such long periods requires the construction of reliable models from short-time experimental data. Two complementary approaches for modelling dry oxidation have been considered. First, basic models following simple analytical laws from classical oxidation theories have been adjusted on the apparent activation energy of oxidation deduced from experimental data. Their extrapolation to long oxidation periods confirms that the expected damage due to dry oxidation could be small. Second, a numerical model able to take in consideration several mechanisms controlling the oxide scale growth is under development. Several preliminary results are presented. (authors)

  20. Global Spent Fuel Logistics Systems Study (GSFLS). Volume 2. GSFLS visit findings and evaluations. Interim report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-01-31

    This report is a part of the interim report documentation for the Global Spent Fuel Logistics System (GSFLS) study. This report describes a global framework that evaluates spent fuel disposition requirements, influencing factors and strategies. A broad sampling of foreign governmental officials, electric utility spokesmen and nuclear power industry officials responsible for GSFLS policies, plans and programs were surveyed as to their views with respect to national and international GSFLS related considerations. The results of these GSFLS visit findings are presented herein. These findings were then evaluated in terms of technical, institutional and legal/regulatory implications. The GSFLS evaluations, in conjunction with perceived US spent fuel objectives, formed the basis for selecting a set of GSFLS strategies which are reported herein.

  1. Global Spent Fuel Logistics Systems Study (GSFLS). Volume 2. GSFLS visit findings and evaluations. Interim report

    International Nuclear Information System (INIS)

    1978-01-01

    This report is a part of the interim report documentation for the Global Spent Fuel Logistics System (GSFLS) study. This report describes a global framework that evaluates spent fuel disposition requirements, influencing factors and strategies. A broad sampling of foreign governmental officials, electric utility spokesmen and nuclear power industry officials responsible for GSFLS policies, plans and programs were surveyed as to their views with respect to national and international GSFLS related considerations. The results of these GSFLS visit findings are presented herein. These findings were then evaluated in terms of technical, institutional and legal/regulatory implications. The GSFLS evaluations, in conjunction with perceived US spent fuel objectives, formed the basis for selecting a set of GSFLS strategies which are reported herein

  2. Scientific criteria document for the development of an interim provincial water quality objective for aniline

    Energy Technology Data Exchange (ETDEWEB)

    Angelow, R.V.; Bazinet, N.

    1996-11-01

    The purpose of this document is to develop an interim provincial water quality objective for aniline for the protection of aquatic life in Ontario. It reviews the sources of aniline in the environment, its environmental fate and properties, acute and chronic toxicity as determined from results reported in the literature on toxicity tests using vertebrates and invertebrates, the bioaccumulation of aniline in the environment, mutagenic effects, and threshold aniline concentrations affecting fish odour and taste. The document then explains the derivation of the interim water quality objective. Water quality criteria for aniline developed in other jurisdictions are noted.

  3. Application and evaluation of interactive 3D PDF for presenting and sharing planning results for liver surgery in clinical routine.

    Directory of Open Access Journals (Sweden)

    Axel Newe

    Full Text Available BACKGROUND & OBJECTIVES: The Portable Document Format (PDF is the de-facto standard for the exchange of electronic documents. It is platform-independent, suitable for the exchange of medical data, and allows for the embedding of three-dimensional (3D surface mesh models. In this article, we present the first clinical routine application of interactive 3D surface mesh models which have been integrated into PDF files for the presentation and the exchange of Computer Assisted Surgery Planning (CASP results in liver surgery. We aimed to prove the feasibility of applying 3D PDF in medical reporting and investigated the user experience with this new technology. METHODS: We developed an interactive 3D PDF report document format and implemented a software tool to create these reports automatically. After more than 1000 liver CASP cases that have been reported in clinical routine using our 3D PDF report, an international user survey was carried out online to evaluate the user experience. RESULTS: Our solution enables the user to interactively explore the anatomical configuration and to have different analyses and various resection proposals displayed within a 3D PDF document covering only a single page that acts more like a software application than like a typical PDF file ("PDF App". The new 3D PDF report offers many advantages over the previous solutions. According to the results of the online survey, the users have assessed the pragmatic quality (functionality, usability, perspicuity, efficiency as well as the hedonic quality (attractiveness, novelty very positively. CONCLUSION: The usage of 3D PDF for reporting and sharing CASP results is feasible and well accepted by the target audience. Using interactive PDF with embedded 3D models is an enabler for presenting and exchanging complex medical information in an easy and platform-independent way. Medical staff as well as patients can benefit from the possibilities provided by 3D PDF. Our results open

  4. Correlates of Nine-Month Retention following Interim Buprenorphine-Naloxone Treatment in Opioid Dependence: A Pilot Study

    Directory of Open Access Journals (Sweden)

    A. Håkansson

    2016-01-01

    Full Text Available Interim medication-only treatment has been suggested for the initiation of opioid maintenance treatment (OMT in opioid-dependent subjects, but this rarely has been studied using buprenorphine instead of methadone. Following a pilot trial assessing interim buprenorphine-naloxone treatment in order to facilitate transfer into OMT, we here aimed to study retention, and potential correlates of retention, in full-scale treatment. Thirty-six patients successfully referred from a waiting list through an interim treatment phase were followed for nine months in OMT. Baseline characteristics, as well as urine analyses during the interim phase and during full-scale OMT, were studied as potential correlates of retention. The nine-month retention in OMT was 83 percent (n=30. While interim-phase urine samples positive for benzodiazepines did not significantly predict dropout from full-scale OMT (p=0.09, urine samples positive for benzodiazepines within full-scale OMT were significantly associated with dropout (p<0.01, in contrast to other substances and baseline characteristics. Retention remained high through nine months in this pilot study sample of patients referred through buprenorphine-naloxone interim treatment, but use of benzodiazepines is problematic, and the present data suggest that it may be associated with treatment dropout.

  5. Interim remedial measures proposed plan for the 200-ZP-1 Operable Unit, Hanford Site, Washington

    International Nuclear Information System (INIS)

    Parker, D.L.

    1993-12-01

    The purpose of this interim remedial measures (IRM) proposed plan is to present and solicit public comments on the IRM planned for the 200-ZP-1 Operable Unit at the Hanford Site in Washington state. The 200-ZP-1 is one of two operable units that envelop the groundwater beneath the 200 West Area of the Hanford Site

  6. results

    Directory of Open Access Journals (Sweden)

    Salabura Piotr

    2017-01-01

    Full Text Available HADES experiment at GSI is the only high precision experiment probing nuclear matter in the beam energy range of a few AGeV. Pion, proton and ion beams are used to study rare dielectron and strangeness probes to diagnose properties of strongly interacting matter in this energy regime. Selected results from p + A and A + A collisions are presented and discussed.

  7. Nuclear waste: Is there a need for federal interim storage

    International Nuclear Information System (INIS)

    1989-01-01

    The Congress created the Monitored Retrievable Storage Review Commission to provide a report on the need for a Federal monitored retrievable storage facility (MRS) as part of the Nation's nuclear waste management system. The Commission concludes that the MRS as presently described in the law, which links the capacity and schedule of operation of the MRS to a permanent geologic repository, cannot be justified. The Commission finds, however, that while no single factor would favor an MRS over the No-MRS option, cumulatively the advantages of an MRS would justify the building of an MRS if: there were no linkages between the MRS and the repository; the MRS could be constructed at an early date; and the opening of the repository were delayed considerably beyond its presently scheduled date of operation. The Commission therefore recommends that the Congress take the following actions: Authorize construction of a Federal Emergency Storage facility with a capacity limit of 2,000 metric tons of uranium; Authorize construction of a User-Funded Interim Storage facility with a capacity limit of 5,000 metric tons of uranium; Reconsider the subject of interim storage by the year 2000

  8. [The long-term results of the application of the combined rehabilitative treatment in the patients presenting with knee osteoarthrosis].

    Science.gov (United States)

    Razumov, A N; Purigа, A O; Yurova, O V

    2015-01-01

    The rehabilitative treatment of the patients suffering from knee osteoarthrosis (OA) up-to-date remains one of the most important medical and social problems of modern medicine due to the high prevalence of this disease, heavy morbidity, and the significant deterioration of the quality of the patients' life. The objective of the present study was to evaluate the long-term results of the combined application of radon and extracorporeal shock-wave therapy for the rehabilitation of the patients presenting with knee OA. The study involved 75 patients at the age from 35 to 62 years with the confirmed diagnosis of stage II and III knee osteoarthrosis. They were divided into 3 groups. Those comprising the main group received extracorporeal shock-wave therapy in combination with the treatment based on the use of radon baths. The patients included in the group of comparison were given a course of radon therapy alone while the patients of the control group received the standard treatment including physiotherapy, magnetic therapy, and the use of non-steroidal anti-inflammatory drugs (NSAIDs). The study has demonstrated the high effectiveness of the combined application of the radon baths and extracorporeal shock-wave therapy that was manifested as the substantial decrease of pain intensity, the increased range of motion in the knee joints, and the improvement of the general quality of life. These beneficial effects persisted during a period of up to 12 months. The stable remission was documented in 82% of the patients comprising the main group. The data obtained give reason to recommend the method employed in the present study for the extensive practical application at different stages of medical rehabilitation of the patients presenting with knee osteoarthrosis.

  9. Application and evaluation of interactive 3D PDF for presenting and sharing planning results for liver surgery in clinical routine.

    Science.gov (United States)

    Newe, Axel; Becker, Linda; Schenk, Andrea

    2014-01-01

    The Portable Document Format (PDF) is the de-facto standard for the exchange of electronic documents. It is platform-independent, suitable for the exchange of medical data, and allows for the embedding of three-dimensional (3D) surface mesh models. In this article, we present the first clinical routine application of interactive 3D surface mesh models which have been integrated into PDF files for the presentation and the exchange of Computer Assisted Surgery Planning (CASP) results in liver surgery. We aimed to prove the feasibility of applying 3D PDF in medical reporting and investigated the user experience with this new technology. We developed an interactive 3D PDF report document format and implemented a software tool to create these reports automatically. After more than 1000 liver CASP cases that have been reported in clinical routine using our 3D PDF report, an international user survey was carried out online to evaluate the user experience. Our solution enables the user to interactively explore the anatomical configuration and to have different analyses and various resection proposals displayed within a 3D PDF document covering only a single page that acts more like a software application than like a typical PDF file ("PDF App"). The new 3D PDF report offers many advantages over the previous solutions. According to the results of the online survey, the users have assessed the pragmatic quality (functionality, usability, perspicuity, efficiency) as well as the hedonic quality (attractiveness, novelty) very positively. The usage of 3D PDF for reporting and sharing CASP results is feasible and well accepted by the target audience. Using interactive PDF with embedded 3D models is an enabler for presenting and exchanging complex medical information in an easy and platform-independent way. Medical staff as well as patients can benefit from the possibilities provided by 3D PDF. Our results open the door for a wider use of this new technology, since the basic idea

  10. Cost studies concerning decontamination and dismantling. The interim store for spent fuel at Studsvik

    International Nuclear Information System (INIS)

    Sjoeblom, Rolf; Sjoeoe, Cecilia; Lindskog, Staffan; Cato, Anna

    2006-04-01

    The interim store for spent fuel at Studsvik was designed and constructed in 1962-64. It has been used for wet storage of fuel from the Aagesta Nuclear Power Plant as well as the R2 reactor at Studsvik. The interim store comprises three cylindrical pools for fuel storage as well as equipment for handling and decontamination. The purpose of the present work is to develop methodology for calculation of future costs for decontamination and dismantling of nuclear research facilities. The analysis is based on information from Studsvik as well as results from information searches. The requirements on precision of cost calculations is high, also at early stages. The reason for this is that the funds are to be collected now but are to be used some time in the future. At the same time they should neither be insufficient nor superfluous. It is apparent from the compilation and analysis that when methodology that has been developed for the purpose of cost calculations for power reactors is applied to research facilities certain drawbacks become apparent, e.g. difficulties to carry out variation analyses. Generally, feedback of data on incurred costs for the purpose of cost calculations can be achieved by using one or more scaling factors together with weighing factors which are established based on e.g. expert judgement. For development and utilisation of such tools it is necessary to have access to estimated costs together with incurred ones. In the report, the following combination of aspects is identified as being of primary significance for achieving a high precision: Calculations with the possibility to calibrate against incurred costs; Radiological surveying tailored to the needs for calculations; Technical planning including selection of techniques to be used; Identification of potential sources for systematic deviations. In the case of the interim store, some of the sources of uncertainty are as follows: Damaged surface layers in the pools; Maintenance status for the

  11. Interim endodontic therapy for alveolar socket bone regeneration of infected hopeless teeth prior to implant therapy.

    Science.gov (United States)

    Rass, Marwan Abou

    2010-01-01

    The immediate placement of implants in the fresh extraction sockets of infected teeth with periradicular and periapical lesions is contraindicated because of both the infection and the loss of architecture required for proper implant placement. There are 4 approaches for implant replacement of a hopeless tooth with lesions: (1) extraction and delayed implant placement; (2) extraction, debridement, guided bone regeneration (GBR), guided tissue regeneration (GTR), and delayed implant placement; (3) extraction, intrasocket debridement, and immediate implant placement; or (4) extraction, debridement, GBR, GTR, and simultaneous implant placement. The extraction of such hopeless teeth often results in large bone and soft tissue defects that are difficult to repair. This article introduces an alternative approach: interim endodontic implant site preparation, defined as a transitional, surgical, or nonsurgical endodontic treatment to regenerate the hopeless tooth bone defects and prepare the site for proper implant placement. This article describes 3 distinct interim endodontic protocols used to manage 5 patients, all of whom had severely infected hopeless teeth with large lesions and were treatment planned for implant replacement: the first, interim nonsurgical endodontic treatment to restore the normal anatomy of the infected hopeless tooth; the second, interim surgical endodontics on the hopeless tooth with preexisting endodontic treatment to regenerate apical bone for primary implant stability, thus avoiding the involvement of the maxillary sinus and other critical anatomic structures; and the third, interim surgical endodontics on the hopeless tooth with preexisting endodontic treatment to confine the size of the osseous defect and simplify the GBR and GTR procedures. The outcome of interim endodontic treatment on these 5 patients demonstrated that tooth extraction would have been a less predictable approach. The interim treatment changed the overall direction of the

  12. Poor predictive value of positive interim FDG-PET/CT in primary mediastinal large B-cell lymphoma

    Energy Technology Data Exchange (ETDEWEB)

    Lazarovici, Julien; Petrovanu, Cynthia; Danu, Alina; Ferme, Christophe; Ribrag, Vincent; Ghez, David [Gustave Roussy, Villejuif (France). Dept. of Hematology; Paris Saclay Univ., Saint-Aubin (France); Terroir, Marie [Gustave Roussy, Villejuif (France). Dept. of Nuclear Medicine and Endocrine Oncology; Paris Saclay Univ., Saint-Aubin (France); Arfi-Rouche, Julia [Gustave Roussy, Villejuif (France). Dept. of Radiology; Paris Saclay Univ., Saint-Aubin (France); Michot, Jean-Marie [Gustave Roussy, Villejuif (France). Dept. of Drug Development (DITEP); Paris Saclay Univ., Saint-Aubin (France); Mussot, Sacha; Florea, Valentina [Marie Lannelongue Hospital, Le Plessis Robinson (France). Dept. of Thoracic Surgery; Ghigna, Maria-Rosa [Marie Lannelongue Hospital, Le Plessis Robinson (France). Dept. of Pathology; Dartigues, Peggy [Gustave Roussy, Villejuif (France). Dept. of Pathology; Paris Saclay Univ., Saint-Aubin (France)

    2017-11-15

    Though commonly used to assess response to therapy, the prognostic value of interim FDG-PET/CT in Primary Mediastinal Large B-cell Lymphoma (PMBCL) is unclear. We conducted a retrospective study on 36 consecutive patients treated at our institution for a PMBCL between 2006 and 2014. All patients with a positive interim FDG-PET/CT had undergone histological restaging consisting either in a surgical debulking of the residual lesion (15 patients) or a CT-guided core needle biopsy (two patients). All FDG-PET/CT were secondarily reviewed according to the more recent Deauville criteria. Interim FDG-PET/CT was considered positive in 17/36 patients using visual evaluation. Among these patients, 14 had a Deauville score of 4. Histological restaging was negative in all but one case, showing inflammation and/or fibrosis. After a median follow-up of 48.5 months, a total of five patients have relapsed, two patients in the positive FDG-PET/CT group, and three patients in the negative FDG-PET/CT group, respectively. These data indicate that a positive interim FDG-PET/CT does not reflect persistence of active disease in the vast majority of PMBCL cases. The relapse rate appears similar regardless of interim FDG-PET/CT results and interpretation criteria. This suggests that interim FDG-PET/CT has a poor positive predictive value, thus kt should be used with caution in PMBCL. (orig.)

  13. Childhood sarcoidosis in Denmark 1979-1994: incidence, clinical features and laboratory results at presentation in 48 children

    DEFF Research Database (Denmark)

    Hoffmann, A L; Milman, N; Byg, K E

    2004-01-01

    .7-15). In 1979-1994 the incidence was 0.29 per 100000 person-years y of age. The incidence was 0.06 in children y of age and increased gradually with age to 1.02 in children aged 14-15 y. General malaise, fever, weight loss, abdominal discomfort, respiratory symptoms, lymphadenopathy......AIM: To describe the incidence, clinical presentation and paraclinical findings in childhood sarcoidosis in Denmark, 1979-1994. METHODS: Patients (n = 5536) with a diagnosis of sarcoidosis were drawn from the nationwide Patient Registry; 81 patients were y of age. The diagnosis...... of sarcoidosis was reconfirmed in 48/81 (59%) patients. In 35/48 (73%) patients, diagnosis was verified by histology, and in 13 it was substantiated by paraclinical/clinical findings. RESULTS: The series comprised 26 boys and 22 girls (male/female ratio 1.18). Median age at diagnosis was 13 y (range 0...

  14. Distribution of hemoglobinopathies in patients presenting for electrophoresis and comparison of result with High performance liquid chromatography

    Directory of Open Access Journals (Sweden)

    R Jha

    2015-09-01

    Full Text Available Background: Nearly 226 million carriers of thalassemias and abnormal hemoglobin are present worldwide according to the World Health Organization (WHO. The laboratory plays an important role in the investigation of the thalassemias and hemoglobinopathies. Cellulose acetate electrophoresis at alkaline pH and diagnosis based mainly on visual impression of thickness of band may miss the thalassemic trait patients. The aim of this study was to find out different hemoglobinopathies and thalassemia presenting in our hospital and to compare electrophoresis results with HPLC.Materials and Methods: This study was performed in the hematopathology section of Department of Pathology of Tribhuvan University Teaching Hospital on cases sent for electrophoresis during 18 months period from October 2013 to March 2015 and included hemoglobinopathies and thalassemias identified by either electrophoresis or HPLC. 97 cases fulfilled the inclusion criteria and thus were included in the study. Electrophoresis at alkaline pH was done in all whereas HPLC was performed in 27 cases.Results: A sharp peak of hemoglobinopathies and thalassemias was seen in Tharu community though other communities are also affected. Thalassemia trait was the most common diagnosis (26.8% followed by sickle cell anemia (21.6%.  Electrophoresis was efficient in detecting some alpha thalassemia variants but missed many cases of beta thalassemia trait.Conclusion: Beta Thalassemia trait and sickle cell anemia both are common in Nepal , along with some other hemoglobinopathies  A sharp peak of hemoglobinopathies and thalassemias are seen in Tharu community. These abnormal hemoglobins and thalassemias are mainly seen in Terai region. Electrophoresis fails to quantify hemoglobin percentage and thus is not appropriate test in beta thalassemia screening. 

  15. THE INTERIM EXPERTS’ COUNCIL RESOLUTION ON THE EMPA-REG OUTCOME TRIAL ISSUES

    Directory of Open Access Journals (Sweden)

    M. V. Shestakova

    2016-01-01

    Full Text Available The interdisciplinary interim experts’ council on March 3, 2016 in Moscow have considered the EMPA-REG OUTCOME trial results and suggested a number of propositions and recommendations on further empagliflozin’s cardiovascular effects investigation and its clinical application in patients with type 2 diabetes at high cardiovascular risk.

  16. 24 CFR 982.516 - Family income and composition: Regular and interim examinations.

    Science.gov (United States)

    2010-04-01

    ... VOUCHER PROGRAM Rent and Housing Assistance Payment § 982.516 Family income and composition: Regular and... assistance payment. (For a voucher tenancy, the housing assistance payment shall be calculated in accordance... the housing assistance payment resulting from an interim redetermination. (2) At the effective date of...

  17. Alternatives generation and analysis report for immobilized low-level waste interim storage architecture

    Energy Technology Data Exchange (ETDEWEB)

    Burbank, D.A., Westinghouse Hanford

    1996-09-01

    The Immobilized Low-Level Waste Interim Storage subproject will provide storage capacity for immobilized low-level waste product sold to the U.S. Department of Energy by the privatization contractor. This report describes alternative Immobilized Low-Level Waste storage system architectures, evaluation criteria, and evaluation results to support the Immobilized Low-Level Waste storage system architecture selection decision process.

  18. KMWin--a convenient tool for graphical presentation of results from Kaplan-Meier survival time analysis.

    Directory of Open Access Journals (Sweden)

    Arnd Gross

    Full Text Available BACKGROUND: Analysis of clinical studies often necessitates multiple graphical representations of the results. Many professional software packages are available for this purpose. Most packages are either only commercially available or hard to use especially if one aims to generate or customize a huge number of similar graphical outputs. We developed a new, freely available software tool called KMWin (Kaplan-Meier for Windows facilitating Kaplan-Meier survival time analysis. KMWin is based on the statistical software environment R and provides an easy to use graphical interface. Survival time data can be supplied as SPSS (sav, SAS export (xpt or text file (dat, which is also a common export format of other applications such as Excel. Figures can directly be exported in any graphical file format supported by R. RESULTS: On the basis of a working example, we demonstrate how to use KMWin and present its main functions. We show how to control the interface, customize the graphical output, and analyse survival time data. A number of comparisons are performed between KMWin and SPSS regarding graphical output, statistical output, data management and development. Although the general functionality of SPSS is larger, KMWin comprises a number of features useful for survival time analysis in clinical trials and other applications. These are for example number of cases and number of cases under risk within the figure or provision of a queue system for repetitive analyses of updated data sets. Moreover, major adjustments of graphical settings can be performed easily on a single window. CONCLUSIONS: We conclude that our tool is well suited and convenient for repetitive analyses of survival time data. It can be used by non-statisticians and provides often used functions as well as functions which are not supplied by standard software packages. The software is routinely applied in several clinical study groups.

  19. INDICATOR AND PATHOGENIC MICROORGANISMS CONTAMINATION OF HIDE OF CATTLE PRESENTED TO FOR SLAUGHTER AND CONTAMINATION OF THE RESULTANT CARCASSES

    Directory of Open Access Journals (Sweden)

    G. Liuzzo

    2011-01-01

    Full Text Available Foodborne pathogens including Escherichia coli O157:H7, Salmonella spp. and Campylobacter spp., can enter the meat chain at multiple points. Animals with excessively dirty hides will represent a risk of cross-contaminations during transport, in the slaughtered house environment and during dressing procedures. The aim of this work was to investigate the relationship among hygiene indicator microorganisms (Enterobacteriaceae and Escherichia coli count, in hide and carcass of cattle presented for slaughter, and different hide cleanliness level in two abattoir (R and F and estimate the prevalence of pathogens Escherichia coli O157:H7, Salmonella spp and Campylobacter spp. in hide and carcass of dirty animals. The results showed that hide Escherichia coli and Enterobacteriaceae count were significantly higher in dirty animals than in clean animals (P<0,05, but carcass contamination were significantly higher in dirty animals than in clean animals only in R abattoir. Escherichia coli O 157:H7 was detected in 19 samples of hide (40,4%, and 2 samples of carcass. Campylobacter jejuni was isolated in 13 samples of hide (25,5% and one sample of carcass. Salmonella spp. were not found in all the samples of hide and carcass.

  20. Individual shareholders’ understanding of the content of interim reports of South African listed retail companies

    Directory of Open Access Journals (Sweden)

    Johan GI Oberholster

    2015-05-01

    Full Text Available A number of studies conducted, and reports published, by international and local accounting bodies have found that the proliferation of disclosures in financial reports has hampered users’ understanding of these reports. The reports by accounting bodies also indicate that these users prefer more concise financial reports. These findings, in conjunction with a dearth of recent questionnaire-based research on whether individual shareholders understand the content of financial reports, resulted in this study on whether individual shareholders understand the content of interim reports. The study provides empirical proof that a sound knowledge of business, accounting and economic matters is a prerequisite for understanding interim reports in the case of individual shareholders. The results of the study indicate that individual shareholders have a limited understanding of the content of interim reports as a whole, and that a good knowledge of business and economic matters and of accounting results in an improved understanding of the content of interim reports. In particular, specialisation in accounting in undergraduate and postgraduate degrees, professional qualifications, and work experience in the financial field improve the understanding of individual shareholders.

  1. The effect of incorporation, orientation and silane treatment of glass fibers on the fracture resistance of interim fixed partial dentures.

    Science.gov (United States)

    Basant, Gupta; Reddy, Y G

    2011-03-01

    Fracture of interim fixed partial dentures (FPD) is of important concern to the dental surgeon, especially with long-span fixed partial dentures or areas of heavy occlusal stress. Polymers used in interim FPDs, reinforced with glass fibers have shown to have a positive effect on the fracture resistance of interim FPDs. Since little research has been done on the influence of silane treated glass fibers on the fracture resistance of interim FPDs, this study was conducted to evaluate the effect of silane treatment of glass fibers on the fracture resistance of interim FPDs and its correlation with the position of fiber reinforcement and length of the span of the interim FPD. Interim FPDs were fabricated from an autopolymerizing polymethyl methacrylate (PMMA) resin. Seven FPDs were made in each group. The FPDs in the control group were unreinforced, and in the other groups the FPDs were reinforced either with non silane treated glass fiber or with silane treated glass fiber. The fibers were placed in two different locations in the FPDs. Three length of span of FPDs were tested. The load was applied to the FPD by a steel ball placed in the center of the pontic space. One Way Anova, Two Way Anova, Studentized range test (Scheffe's). Results showed that the load required for fracturing the unreinforced FPDs varied from 272 to 998 N. Mean fracture load of reinforced FPDs varied from 536 to 1642 N. One-way analysis of variance showed that the position of fibers and the silane treatment fibers significantly affected the fracture load. The results of this study suggested that the silane treatment of glass fibers had a marked improvement in the fracture resistance of FPDs as compared to untreated glass fibers. Selective placement of the glass fibers at the undersurface of the pontic and the occlusal surface of the interim fixed partial denture showed more increase in the fracture resistance as compared to the randomly distributed glass fibers. The glass fiber reinforcement is

  2. Neuro-ophthalmic presentation and surgical results of unruptured intracranial aneurysms—prospective Helsinki experience of 142 patients.

    Science.gov (United States)

    Koskela, Elina; Setälä, Kirsi; Kivisaari, Riku; Hernesniemi, Juha; Laakso, Aki

    2015-04-01

    To assess prospectively neuro-ophthalmic findings associated with unruptured intracranial aneurysms and treatment morbidity and to identify factors predicting these findings. Patients admitted to Helsinki University Central Hospital and treated surgically or endovascularly during 2011 underwent a neuro-ophthalmic examination, including formal visual field testing, before operation, at discharge, and 2-4 months and ≥6 months postoperatively. Univariate and multivariate analysis was used to identify factors predicting eye movement disorders. Study participants included 142 patients with 184 treated aneurysms: 7 (5%) had a third, fourth, or sixth nerve palsy or skew deviation preoperatively, and 16 (11%) had a third, fourth, or sixth nerve palsy or skew deviation postoperatively; the frequency was 8 (6%) at the last follow-up evaluation. Other findings included compressive optic neuropathy (n = 4), ischemic optic neuropathy (n = 1), Weber syndrome (n = 3), Benedikt syndrome (n = 1), and Wallenberg syndrome (n = 1). Of the 140 survivors at 6 months, 7 (5%) presented with visual field defects resulting from the aneurysm or its treatment. In the best bivariate model, factors independently predicting postoperative eye movement disorders were aneurysm location in the posterior circulation with an odds ratio of 142.02 (95% confidence interval = 20.13-1002.22) and aneurysm size (odds ratio = 1.28 for each 1-mm increase in diameter, 95% confidence interval = 1.12-1.47). Management of unruptured intracranial aneurysms is fairly safe from a neuro-ophthalmic perspective, with some treatment-related morbidity being transient and minor. Although rare, an irreversible deficit is possible and should be taken into account when considering preventive treatment. Copyright © 2015 Elsevier Inc. All rights reserved.

  3. Lutonix® 014 DCB global Below the Knee Registry Study: interim 6-month outcomes.

    Science.gov (United States)

    Thieme, Marcus; Lichtenberg, Michael; Brodmann, Marianne; Cioppa, Angelo; Scheinert, Dierk

    2018-04-01

    The most common clinical presentation of peripheral artery disease (PAD) comprises intermittent claudication (IC), but about one third of patients will progress to critical limb ischemia (CLI), characterized by rest pain and/or tissue loss, which is the most severe limb manifestation of PAD. Paclitaxel-coated balloons are well established for the endovascular treatment of femoropopliteal lesions in patients with IC and CLI. This ongoing multicenter registry study is exploring the role of the Lutonix® 014 drug-coated balloon (DCB) in the treatment of below-the-knee (BTK) arteries and CLI. Three hundred fourteen (314) patients were enrolled from 26 sites and 12 countries. The real-world patients represent those undergoing intervention for BTK arteries with the Lutonix® 014 DCB. The study had both, primary safety and primary efficacy endpoints. The primary safety endpoint was freedom at 30 days from BTK major adverse limb event (MALE) + perioperative death (POD). Primary efficacy was freedom from clinically driven target lesion reintervention (fTLR) at 6 months. Additional secondary endpoints related to safety were reported. The interim 6 months' results showed freedom from MALE and POD at 30 days of 98.6% and at 6 months (180 days) of 96.0%. Primary efficacy of fTLR at 6 months (180 days) was 87.9%. Safety related secondary endpoints at 6 months (180 days) showed freedom from all of the following: all cause death of 91.2%, above ankle amputation 97.1%, reintervention for thrombosis 95.2%, reintervention for distal embolization 100.0%, and target vessel revascularization of 88.0%. There were no unexpected device or drug related events reported. The interim 6-month outcomes demonstrate the safety and efficacy of the Lutonix® 014 DCB for the treatment of BTK arteries.

  4. Seal capability of interim post and core crown with temporary cements.

    Science.gov (United States)

    Bönecker-Valverde, Guilherme; Maniglia-Ferreira, Claudio; Abi-Rached, Gisele Priscila; Gomes, Brenda Paula Figueiredo de Almeida; Mesquita, Marcelo Ferraz

    2010-01-01

    The purpose of the present study was to evaluate the in vitro seal capability of interim post and core crown restorations. Eighty teeth were selected and divided into 8 groups. Four experimental groups received interim posts and core crowns. Half of each group was decoronated at the cementum-enamel junction, groups PCCH and PCZO. The other half was sectioned 2 mm coronal to the cementum-enamel junction, groups PCrZO and PCrCH. The interim post and core crowns were luted with Rely X Temp NE, groups PCrZO and PCZO; Hydro C was used for Groups PCrCH and PCCH. The control groups, PC and PCr, received uncoated post and core crowns; groups OTg and OT were left without interim post and core crowns and were totally open. Infiltration was accessed by dye exposure followed by demineralization of the teeth. The length of the infiltration was measured using digital images taken from the specimens. The images were inserted into the Image Tool 3.0 software. Kruskal-Wallis analysis of variance and Dunn's multiple comparison method were used to test for significant differences among test groups (P crowns will be subject to leakage. Ethics Committee: 095/2008.

  5. First-year students’ essay writing practices: Formative feedback and interim literacies

    Directory of Open Access Journals (Sweden)

    Emmanuel Esambe

    2016-03-01

    Full Text Available The varying literacy standards that undergraduate students represent are a reflection of their interim grasp of academic literacy (Paxton 2007. The aim of this study is to analyse a small group of undergraduate first-year students’ depiction of their interim grasp of academic writing and to reflect on how lecturers use formative feedback to respond to specific issues regarding students’ academic transitions within their discipline. Using an emancipatory methodology, this study was designed as a participatory action research. Qualitative data from focus group interviews with lecturers and photovoice presentations by first-year dental technology students were used to explore how students demonstrated their interim grasp of academic essay writing in a Health Science department at a university of technology. However, this article, which is part of a broader study, analyses a small class of first-year students’ depiction of their interim grasp of essay writing and reflects on how their lecturers use formative feedback to respond to these students’ academic transitions within their discipline. Using activity theory and morphogenetic realist theory to analyse essay writing activities during an intervention, the study reveals that images are potent artefacts that students and lecturers use to build meaningful dialogue during essay writing in an uneven terrain.

  6. Interim FDG-PET Scan in Hodgkin's Lymphoma: Hopes and Caveats

    Directory of Open Access Journals (Sweden)

    M. André

    2011-01-01

    Full Text Available FDG-PET has recently emerged as an important tool for the management of Hodgkins lymphoma. Although its use for initial staging and response evaluation at the end of treatment is well established, the place of interim PET for response assessment and subsequent treatment tailoring is still quite controversial. The use of interim PET after a few cycles of chemotherapy may allow treatment reduction for good responders, leading to lesser treatment toxicities as well as early treatment adaptation for bad responders with a potential higher chance for cure. Interpretation of interim PET is a rapidly moving field. Actually, visual interpretation is preferred over quantitative interpretation in this situation. The notion of minimal residual uptake emerged for faint persisting FDG uptake, but has evolved during the recent years. Guidelines using mediastinum and liver as references have been proposed at the expert meeting in Deauville 2009. Actually, several trials are ongoing both for localised and advanced disease to evaluate the FDG-PET potential for early treatment monitoring and tailoring. Until the results of these prospective randomized trials become available, treatment changes according to the interim PET results should remain inappropriate and limited to well-conducted clinical trials.

  7. SNF Interim Storage Canister Corrosion and Surface Environment Investigations

    Energy Technology Data Exchange (ETDEWEB)

    Bryan, Charles R. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Enos, David G. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States)

    2015-09-01

    This progress report describes work being done at Sandia National Laboratories (SNL) to assess the localized corrosion performance of container/cask materials used in the interim storage of spent nuclear fuel (SNF). Of particular concern is stress corrosion cracking (SCC), by which a through-wall crack could potentially form in a canister outer wall over time intervals that are shorter than possible dry storage times. In order for SCC to occur, three criteria must be met. A corrosive environment must be present on the canister surface, the metal must susceptible to SCC, and sufficient tensile stress to support SCC must be present through the entire thickness of the canister wall. SNL is currently evaluating the potential for each of these criteria to be met.

  8. Prediction of Pathological Complete Response to Neoadjuvant Chemotherapy for Primary Breast Cancer Comparing Interim Ultrasound, Shear Wave Elastography and MRI.

    Science.gov (United States)

    Evans, Andrew; Whelehan, Patsy; Thompson, Alastair; Purdie, Colin; Jordan, Lee; Macaskill, Jane; Waugh, Shelley; Fuller-Pace, Frances; Brauer, Katrin; Vinnicombe, Sarah

    2017-09-21

    Background  Prediction of pathological complete response (pCR) of primary breast cancer to neoadjuvant chemotherapy (NACT) may influence planned surgical approaches in the breast and axilla. The aim of this project is to assess the value of interim shear wave elastography (SWE), ultrasound (US) and magnetic resonance imaging (MRI) after 3 cycles in predicting pCR. Methods  64 patients receiving NACT had baseline and interim US, SWE and MRI examinations. The mean lesion stiffness at SWE, US and MRI diameter was measured at both time points. We compared four parameters with pCR status: a) Interim mean stiffness ≤ or > 50 kPa; b) Percentage stiffness reduction; c) Percentage US diameter reduction and d) Interim MRI response using RECIST criteria. The Chi square test was used to assess significance. ResultsInterim stiffness of ≤ or > 50 kPa gave the best prediction of pCR with pCR seen in 10 of 14 (71 %) cancers with an interim stiffness of ≤ 50 kPa, compared to 7 of 50 (14 %) of cancers with an interim stiffness of > 50 kPa, (p  30 % (sensitivity 50 % and specificity 79 %, p = 0.03) and % reduction in US diameter (sensitivity 47 %, specificity 81 %, p = 0.03). Similar results were obtained from ROC analysis. Conclusion  SWE stiffness of breast cancers after 3 cycles of NACT and changes in stiffness from baseline are strongly associated with pCR after 6 cycles. © Georg Thieme Verlag KG Stuttgart · New York.

  9. Real-world experience with a Paclitaxel-Coated Balloon for the treatment of atherosclerotic infrainguinal arteries: 12-month interim results of the BIOLUX P-III registry first year of enrolment

    Directory of Open Access Journals (Sweden)

    Marianne Brodmann

    Full Text Available Abstract Background Endovascular management of atherosclerotic infrainguinal arteries recently shifted towards drug eluting devices, designed to locally prevent the restenosis process. Numerous clinical studies report an advantage of drug coated balloons over uncoated balloon angioplasty in treating lower extremity peripheral artery disease. However, as coating and balloon platforms are different, each device requires dedicated clinical evaluations. Objective The aim of the study is to further investigate the safety and effectiveness of a Paclitaxel-Coated Balloon for the treatment of atherosclerotic infrainguinal arteries in a real-world setting. Methods 203 patients out of a final sample of 882 were enrolled in this prospective multicenter, observational, all-comers registry during the first 12 months. The primary endpoints were major adverse events (defined as procedure or device related death within 30 days post index procedure, clinically-driven target lesion revascularization or major target limb amputation at 6 months and freedom from clinically-driven target lesion revascularization at 12 months. Both endpoints were adjudicated by a Clinical Events Committee. Results Mean patient age was 70.2±10.4 years (60.1% male. 47.3% of the patients were diabetic and 67.5% had a history of smoking. Severe claudication was reported in 37.4% and 40% had critical limb ischemia. 257 lesions, including 13.2% in the infrapopliteal territory, were treated with Passeo-18 Lux (mean lesion length 75.1 mm±69.4, 20% occlusions, 76.3% calcified. At 6 months, the rate of major adverse events was 5.5% (95%CI 3.1-9.7. Freedom from clinically-driven target lesion revascularization at 12 months was 93.2% (95%CI 89.1-95.8. All causes mortality was 6.5% (95%CI 3.8-11.0 and overall amputation rate was 4.2% (95%CI 2.1-8.3 at 12 months. Conclusion In a real-world environment, the BIOLUX P-III registry preliminary results confirm the safety and efficacy of the Paclitaxel

  10. Surface Water Interim Measures/Interim Remedial Action Plan/Environmental Assessment and Decision Document for South Walnut Creek Basin (Operable Unit No. 2)

    International Nuclear Information System (INIS)

    1991-01-01

    The Department of Energy (DOE) is pursuing an Interim Measure/Interim Remedial Action (IM/IRA) at the 903 Pad, Mound, and East Trenches Areas (Operable Unit No. 2) at the Rocky Flats Plant (RFP). This IM/IRA is to be conducted to minimize the release from these areas of hazardous substances that pose a potential threat to the public health and environment. The Plan involved the collection of contaminated surface water at specific locations, treatment by chemical precipitation, cross-flow membrane filtration and granular activated carbon (GAC) adsorption, and surface discharge of treated water. Information for the initial configuration of the Plan is presented in the document entitled ''Proposed Interim Measures/Interim Remedial Action Plan and Decision Document, 903 Pad, Mound, and East Trenches Areas, Operable Unit No. 2'' (IM/IRAP) dated 26 September 1990. Information concerning the proposed Surface Water IM/IRA was presented during a public meeting held from 7 to 10 p.m., Tuesday, 23 October 1990, at the Westminster City Park Recreation Center in Westminster, Colorado. This Responsiveness Summary presents DOE's response to all comments received at the public meeting, as well as those mailed to DOE during the public comment period which ended 24 November 1990. There were a number of technical comments on the plan that DOE has addressed herein. It is noted that several major issues were raised by the comments. Regardless of the estimated low risk to the public from construction and water transport activities, the popular sentiment of the public, based on comments received, is strong concern over worker and public health risks from these activities. In the light of public and municipal concerns, DOE proposes to eliminate from this IM/IRA the interbasin transfer of Woman Creek seepage to the South Walnut Creek drainage and to address collection and treatment of contaminated South Walnut Creek and Woman Creek surface water under two separate IM/IRAs

  11. Subsurface Interim Measures/Interim Remedial Action Plan and Decision Document for the 903 Pad, Mound, and East Trenches Areas (Operable Unit No. 2)

    International Nuclear Information System (INIS)

    1992-01-01

    The Department of Energy (DOE) is pursuing an Interim Measure/Interim Remedial Action (IM/IRA) at the 903 Pad, Mound, and East Trenches Areas (Operable Unit No. 2) at the Rocky Flats Plant (RFP). This MIRA is to be conducted to provide information that will aid in the selection and design of final remedial actions at OU2 that will address removal of suspected free-phase volatile organic compound (VOC) contamination. The Plan involves investigating the removal of residual free-phase VOCs by in situ vacuum-enhanced vapor extraction technology at 3 suspected VOC source areas within OU2. VOC-contaminated vapors extracted from the subsurface would be treated by granular activated carbon (GAC) adsorption and discharged. The Plan also includes water table depression, when applicable at the test sites, to investigate the performance of vapor extraction technology in the saturated zone. The Plan provides for treatment of any contaminated ground water recovered during the IM/IRA at existing RFP treatment facilities. The proposed MVIRA Plan is presented in the document entitled ''Proposed Subsurface Interim Measures/Interim Remedial Action Plan/Environmental Assessment and Decision Document, 903 Pad, Mound, and East Trenches Areas, Operable Unit No. 2, '' dated 20 March 1992. Information concerning the proposed Subsurface IM/IRA was presented during a DOE Quarterly Review meeting held on 07 April 1992 and a public meeting held on 07 May 1992, at the Marriott Hotel in Golden, Colorado. The Responsiveness Summary presents DOE's response to all comments received at the public meeting, as well as those mailed to date to DOE during the public comment period

  12. Influence of vegetation size on the clinical presentation and outcome of lead-associated endocarditis: results from the MEDIC registry.

    Science.gov (United States)

    Greenspon, Arnold J; Le, Katherine Y; Prutkin, Jordan M; Sohail, M Rizwan; Vikram, Holenarasipur R; Baddour, Larry M; Danik, Stephan B; Peacock, James; Falces, Carlos; Miro, Jose M; Naber, Christoph; Carrillo, Roger G; Tseng, Chi-Hong; Uslan, Daniel Z

    2014-06-01

    The purpose of this study was to determine whether the clinical presentation of lead-associated endocarditis (LAE) is related to the size of lead vegetations and how size is related to bacteriology and clinical outcomes. Cardiac implantable electronic device (CIED) infection may present as either local pocket infection or bloodstream infection with or without LAE. LAE is associated with significant morbidity and mortality. The clinical presentation and course of LAE were evaluated by the MEDIC (Multicenter Electrophysiologic Device Cohort) registry, an international registry enrolling patients with CIED infection. Consecutive LAE patients enrolled in the MEDIC registry between January 1, 2009 and December 31, 2012 were analyzed. The clinical features and outcomes of 2 groups of patients were compared based on the size of the lead vegetation detected by echocardiography (> or vegetation vegetation ≥1 cm in diameter (Group II). Patients in Group I more often presented with signs of local pocket infection, whereas Group II patients presented with clinical evidence of systemic infection. Staphylococcus aureus was the organism most often responsible for LAE, whereas infection with coagulase-negative staphylococci was associated with larger vegetations. Outcomes were improved among those who underwent complete device removal. However, major complications were associated with an open surgical approach for device removal. The clinical presentation of LAE is influenced by the size of the lead vegetation. Prompt recognition and management of LAE depends on obtaining blood cultures and echocardiography, including transesophageal echocardiography, in CIED patients who present with either signs of local pocket or systemic infection. Copyright © 2014 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

  13. Experience collecting interim data on mortality: an example from the RALES study

    Directory of Open Access Journals (Sweden)

    Kulbertus Henri

    2001-02-01

    Full Text Available Abstract Introduction The Randomized Aldactone Evaluation Study (RALES randomized 822 patients to receive 25 mg spironolactone daily and 841 to receive placebo. The primary endpoint was death from all causes. Randomization began on March 24, 1995; recruitment was completed on December 31, 1996; follow-up was scheduled to continue through December 31, 1999. Evidence of a sizeable benefit on mortality emerged early in the RALES. The RALES data safety monitoring board (DSMB, which met semiannually throughout the trial, used a prespecified statistical guideline to recommend stopping for efficacy. At the DSMB's request, its meetings were preceded by an 'endpoint sweep', that is, a census of all participants to confirm their vital status. Methods We used computer simulation to evaluate the effect of the sweeps. Results The sweeps led to an estimated 5 to 8% increase in the number of reported deaths at the fourth and fifth interim analyses. The data crossed the statistical boundary at the fifth interim analysis. If investigators had reported all deaths within the protocol-required 24-h window, the DSMB might have recommended stopping after the fourth interim analysis. Discussion Although endpoint sweeps can cause practical problems at the clinical centers, sweeps are very useful if the intervals between patient visits or contact are long or if endpoints require adjudication by committee, reading center, or central laboratory. Conclusion We recommend that trials with interim analyses institute active reporting of the primary endpoints and endpoint sweeps.

  14. Intercultural Pedagogies: An Interim Stocktaking.

    Science.gov (United States)

    Reich, Hans H.

    1994-01-01

    Presents a survey of educational history specific to immigration in England, France, and West Germany after World War II. Concludes that intercultural pedagogics is passing through a severe crisis that can be surmounted only if previous insights are successfully integrated into fundamentally new developments. (CFR)

  15. 78 FR 70244 - Electronic Interim Assistance Reimbursement Program

    Science.gov (United States)

    2013-11-25

    ... SOCIAL SECURITY ADMINISTRATION 20 CFR Part 416 [Docket No. SSA-2011-0104] RIN 0960-AH45 Electronic Interim Assistance Reimbursement Program AGENCY: Social Security Administration. ACTION: Notice of proposed rulemaking (NPRM). SUMMARY: We reimburse States that provide interim assistance to Supplemental...

  16. Transuranic waste storage and assay facility (TRUSAF) interim safety basis

    International Nuclear Information System (INIS)

    Gibson, K.D.

    1995-09-01

    The TRUSAF ISB is based upon current facility configuration and procedures. The purpose of the document is to provide the basis for interim operation or restrictions on interim operations and the authorization basis for the TRUSAF at the Hanford Site. The previous safety analysis document TRUSAF hazards Identification and Evaluation (WHC 1977) is superseded by this document

  17. 28 CFR 94.41 - Interim emergency payment.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Interim emergency payment. 94.41 Section 94.41 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) CRIME VICTIM SERVICES International Terrorism Victim Expense Reimbursement Program Payment of Claims § 94.41 Interim emergency payment...

  18. General certification procedure of enterprises and interim job enterprises

    CERN Document Server

    Int. At. Energy Agency, Wien

    2002-01-01

    This procedure defines the certification global process of enterprises employing workers of A or B category for nuclear facilities and interim job enterprises proposing workers of A or B category for nuclear facilities. This certification proves the enterprises ability to satisfy the specification ''E'' of the CEFRI and the interim job enterprises to satisfy the specification ''I'' of the CEFRI. (A.L.B.)

  19. Presidential Transition: The Experience of Two Community College Interim Presidents

    Science.gov (United States)

    Thompson, Matthew D.

    2010-01-01

    The purpose of this qualitative case study was to understand the experiences of two community college interim presidents, their characteristics, and how they led institutions following an abrupt presidential departure. There were two fundamental questions framing this research study, 1. How do two interim community college presidents lead…

  20. 50 CFR 660.720 - Interim protection for sea turtles.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Interim protection for sea turtles. 660.720 Section 660.720 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND... Migratory Fisheries § 660.720 Interim protection for sea turtles. (a) Until the effective date of §§ 660.707...

  1. Early interim {sup 18}F-FDG PET in Hodgkin's lymphoma: evaluation on 304 patients

    Energy Technology Data Exchange (ETDEWEB)

    Zinzani, Pier Luigi; Stefoni, Vittorio; Broccoli, Alessandro; Argnani, Lisa; Baccarani, Michele [University of Bologna, Institute of Hematology and Medical Oncology ' ' L. e A. Seragnoli' ' , Policlinico ' ' Sant' Orsola-Malpighi' ' , Bologna (Italy); Rigacci, Luigi; Puccini, Benedetta [Azienda Ospedaliero Universitaria ' ' Careggi' ' , Hematology Department, Florence (Italy); Castagnoli, Antonio [Ospedale ' ' Misericordia e Dolce' ' , Nuclear Medicine, Prato (Italy); Vaggelli, Luca [Azienda Ospedaliero Universitaria ' ' Careggi' ' , Nuclear Medicine, Florence (Italy); Zanoni, Lucia; Fanti, Stefano [Policlinico ' ' Sant' Orsola-Malpighi' ' , Department of Nuclear Medicine, Bologna (Italy)

    2012-01-15

    The use of early (interim) PET restaging during first-line therapy of Hodgkin's lymphoma (HL) in clinical practice has considerably increased because of its ability to provide early recognition of treatment failure allowing patients to be transferred to more intensive treatment regimens. Between June 1997 and June 2009, 304 patients with newly diagnosed HL (147 early stage and 157 advanced stage) were treated with the ABVD regimen at two Italian institutions. Patients underwent PET staging and restaging at baseline, after two cycles of therapy and at the end of the treatment. Of the 304 patients, 53 showed a positive interim PET scan and of these only 13 (24.5%) achieved continuous complete remission (CCR), whereas 251 patients showed a negative PET scan and of these 231 (92%) achieved CCR. Comparison between interim PET-positive and interim PET-negative patients indicated a significant association between PET findings and 9-year progression-free survival and 9-year overall survival, with a median follow-up of 31 months. Among the early-stage patients, 19 had a positive interim PET scan and only 4 (21%) achieved CCR; among the 128 patients with a negative interim PET scan, 122 (97.6%) achieved CCR. Among the advanced-stage patients, 34 showed a persistently positive PET scan with only 9 (26.4%) achieving CCR, whereas 123 showed a negative interim PET scan with 109 (88.6%) achieving CCR. Our results demonstrate the role of an early PET scan as a significant step forward in the management of patients with early-stage or advanced-stage HL. (orig.)

  2. "Still Rather Hazy at Present": Citizens' and Physicians' Views on Returning Results from Biobank Research Using Broad Consent.

    Science.gov (United States)

    Barazzetti, Gaia; Cavalli, Samuele; Benaroyo, Lazare; Kaufmann, Alain

    2017-03-01

    Informed consent and return of research results are among the most debated topics in the biobank literature. We discuss ethical, social, and policy issues associated with returning results in the context of biobanks using a broad consent approach, in the light of data from a qualitative survey of citizens' and physicians' views. Data were collected through interviews and focus groups to investigate stakeholders' perspectives about a large-scale hospital-based biobank designed to foster biomedical research, including prospective genomics research, and "personalized" medicine. Both physicians and citizens considered psychosocial impacts as crucial in the assessment of benefits expected from a return of results to biobank participants. In particular, physicians highlighted the possible consequences on the patient-doctor relationship and discussed implications for the concept of "personalized" medicine. Citizens held ambivalent attitudes toward returning individual research results: they defended the "right not to know," while they also considered a sort of "responsibility to know" because of potential implications of results for family members. Moreover, physicians and citizens raised questions about the broad consent model used for inhospital biobank recruitment and expressed their needs for more training in genomics and more information on the biobank initiative. Stakeholders such as citizens and physicians, who may be concerned as potential biobank participants or as healthcare professionals involved in the management of clinically relevant research results, provide useful insights into several aspects of broad consent and return of results, related in particular to the interface between research and the clinic.

  3. Mycobacterial disease in cats in Great Britain: I. Culture results, geographical distribution and clinical presentation of 339 cases.

    Science.gov (United States)

    Gunn-Moore, Danièlle A; McFarland, Sarah E; Brewer, Jacqueline I; Crawshaw, Timothy R; Clifton-Hadley, Richard S; Kovalik, Marcel; Shaw, Darren J

    2011-12-01

    This study investigated 339 cases of feline mycobacterial disease from cats with cutaneous lesions or masses found at exploratory laparotomy. Tissue samples were submitted to the Veterinary Laboratories Agency for mycobacterial culture over a 4-year period to December 2008. The study assessed which species of culturable mycobacteria were involved, where the cats lived, and their clinical presentation (physical findings, serum biochemistry, radiography, feline leukaemia virus and feline immunodeficiency virus status). Mycobacterium microti was cultured from 19%, Mycobacterium bovis 15%, Mycobacterium avium 7%, non-M avium non-tuberculous mycobacteria 6%, with no growth in 53% of samples. M microti, M bovis and M avium were found in almost mutually exclusive clusters within Great Britain (GB) (ie, M bovis in South-West England/Wales/Welsh Border, M avium in eastern England and M microti south of London and in South-West Scotland). While differences were seen in the clinical presentation and distribution of lesions caused by the different infections, these were not sufficiently different to be diagnostic. Cats commonly presented with single or multiple cutaneous lesions (74%), which were sometimes ulcerated or discharging, located most frequently on the head (54%). Lymph nodes were usually involved (47%); typically the submandibular nodes. Systemic or pulmonary signs were rarely seen (10-16%). When a cat is suspected of having mycobacteriosis, accurate identification of the species involved helps to determine appropriate action. Our findings show that knowing the cat's geographic location can be helpful, while the nature of the clinical presentation is less useful. Most cases of feline mycobacterial disease in GB are cutaneous. Copyright © 2011 ISFM and AAFP. Published by Elsevier Ltd. All rights reserved.

  4. Modernization and refurbishment of the Central Interim Storage

    International Nuclear Information System (INIS)

    Mele, I.; Zeleznik, N.

    2002-01-01

    The Central Interim Storage for radioactive waste in Brinje, being put into operation in 1986, needs refurbishment and modernization in order to meet the up-to-date operational and safety requirements and to ensure the normal and undisturbed acceptance of radioactive waste from small producers in the future. Because of the waste, being already stored in the storage, the lack of reprocessing capacities and the lack of auxiliary room, the refurbishment and modernization is a complex problem, which needs to be addressed with care. The plan of refurbishment and modernization requires an integral approach, covering all different aspects of renewal and reconstruction. The implementation plan, however, must be based on the actual state of the storage and real conditions for the implementations: from technical to financial. In this paper the project for refurbishment and modernization of the storage, and some activities that have already been implemented, are presented.(author)

  5. Delayed Presentation of Isolated Complete Pancreatic Transection as a Result of Sport-Related Blunt Trauma to the Abdomen

    Directory of Open Access Journals (Sweden)

    Andrew J. Healey

    2008-01-01

    Full Text Available Introduction: Blunt abdominal trauma is a rare but well-recognized cause of pancreatic transection. A delayed presentation of pancreatic fracture following sport-related blunt trauma with the coexisting diagnostic pitfalls is presented. Case Report: A 17-year-old rugby player was referred to our specialist unit after having been diagnosed with traumatic pancreatic transection, having presented 24 h after a sporting injury. Despite haemodynamic stability, at laparotomy he was found to have a diffuse mesenteric hematoma involving the large and small bowel mesentery, extending down to the sigmoid colon from the splenic flexure, and a large retroperitoneal hematoma arising from the pancreas. The pancreas was completely severed with the superior border of the distal segment remaining attached to the splenic vein that was intact. A distal pancreatectomy with spleen preservation and evacuation of the retroperitoneal hematoma was performed. Discussion/Conclusion: Blunt pancreatic trauma is a serious condition. Diagnosis and treatment may often be delayed, which in turn may drastically increase morbidity and mortality. Diagnostic difficulties apply to both paraclinical and radiological diagnostic methods. A high index of suspicion should be maintained in such cases, with a multi-modality diagnostic approach and prompt surgical intervention as required.

  6. Central waste complex interim safety basis

    International Nuclear Information System (INIS)

    Cain, F.G.

    1995-01-01

    This interim safety basis provides the necessary information to conclude that hazards at the Central Waste Complex are controlled and that current and planned activities at the CWC can be conducted safely. CWC is a multi-facility complex within the Solid Waste Management Complex that receives and stores most of the solid wastes generated and received at the Hanford Site. The solid wastes that will be handled at CWC include both currently stored and newly generated low-level waste, low-level mixed waste, contact-handled transuranic, and contact-handled TRU mixed waste

  7. Central waste complex interim safety basis

    Energy Technology Data Exchange (ETDEWEB)

    Cain, F.G.

    1995-05-15

    This interim safety basis provides the necessary information to conclude that hazards at the Central Waste Complex are controlled and that current and planned activities at the CWC can be conducted safely. CWC is a multi-facility complex within the Solid Waste Management Complex that receives and stores most of the solid wastes generated and received at the Hanford Site. The solid wastes that will be handled at CWC include both currently stored and newly generated low-level waste, low-level mixed waste, contact-handled transuranic, and contact-handled TRU mixed waste.

  8. Results and Lessons Learned Interim Report: Altus AFB Site

    National Research Council Canada - National Science Library

    McHugh, Thomas

    2005-01-01

    ...) to address the critical groundwater-to-indoor-air vapor intrusion pathway. By increasing our understanding of this critical pathway, guidelines can be improved, thereby better focusing Department of Defense (DoD...

  9. Improving of spent fuel monitoring in condition of Slovak wet interim spent fuel storage facility

    International Nuclear Information System (INIS)

    Miklos, M.; Krsjak, V.; Bozik, M.; Vasina, D.

    2008-01-01

    Monitoring of WWER fuel assemblies condition in Slovakia is presented in the paper. The leak tightness results of fuel assemblies used in Slovak WWER units in last 20 years are analyzed. Good experiences with the 'Sipping system' are described. The Slovak wet interim spent fuel storage facility in NPP Jaslovske Bohunice was build and put in operation in 1986. Since 1999, leak tests of WWER-440 fuel assemblies are provided by special leak tightness detection system 'Sipping in Pool' delivered by Framatome-ANP facility with external heating for the precise detection of active specimens. Another system for monitoring of fuel assemblies condition was implemented in December 2006 under the name 'SVYPP-440'. First non-active tests started at February 2007 and are described in the paper. Although those systems seems to be very effective, the detection time of all fuel assemblies in one storage pool is too long (several months). Therefore, a new 'on-line' detection system, based on new sorbent KNiFC-PAN for effective 134 Cs and 137 Cs activity was developed. This sorbent was compared with another type of sorbent NIFSIL and results are presented. The design of this detection system and its possible application in the Slovak wet spent fuel storage facility is discussed. For completeness, the initial results of the new system are also presented. (authors)

  10. The albatross plot: A novel graphical tool for presenting results of diversely reported studies in a systematic review.

    Science.gov (United States)

    Harrison, Sean; Jones, Hayley E; Martin, Richard M; Lewis, Sarah J; Higgins, Julian P T

    2017-09-01

    Meta-analyses combine the results of multiple studies of a common question. Approaches based on effect size estimates from each study are generally regarded as the most informative. However, these methods can only be used if comparable effect sizes can be computed from each study, and this may not be the case due to variation in how the studies were done or limitations in how their results were reported. Other methods, such as vote counting, are then used to summarize the results of these studies, but most of these methods are limited in that they do not provide any indication of the magnitude of effect. We propose a novel plot, the albatross plot, which requires only a 1-sided P value and a total sample size from each study (or equivalently a 2-sided P value, direction of effect and total sample size). The plot allows an approximate examination of underlying effect sizes and the potential to identify sources of heterogeneity across studies. This is achieved by drawing contours showing the range of effect sizes that might lead to each P value for given sample sizes, under simple study designs. We provide examples of albatross plots using data from previous meta-analyses, allowing for comparison of results, and an example from when a meta-analysis was not possible. Copyright © 2017 The Authors. Research Synthesis Methods Published by John Wiley & Sons Ltd.

  11. 50 CFR 259.30 - Application for Interim Capital Construction Fund Agreement (“Interim CCF Agreement”).

    Science.gov (United States)

    2010-10-01

    ...) Date of construction, acquisition, or reconstruction, (vii) Fishery of operation (which in this section... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Application for Interim Capital Construction Fund Agreement (âInterim CCF Agreementâ). 259.30 Section 259.30 Wildlife and Fisheries NATIONAL...

  12. Symbolic universes between present and future of Europe. First results of the map of European societies' cultural milieu.

    Science.gov (United States)

    Salvatore, Sergio; Fini, Viviana; Mannarini, Terri; Veltri, Giuseppe Alessandro; Avdi, Evrinomi; Battaglia, Fiorella; Castro-Tejerina, Jorge; Ciavolino, Enrico; Cremaschi, Marco; Kadianaki, Irini; Kharlamov, Nikita A; Krasteva, Anna; Kullasepp, Katrin; Matsopoulos, Anastassios; Meschiari, Claudia; Mossi, Piergiorgio; Psinas, Polivios; Redd, Rozlyn; Rochira, Alessia; Santarpia, Alfonso; Sammut, Gordon; Valsiner, Jaan; Valmorbida, Antonella

    2018-01-01

    This paper reports the framework, method and main findings of an analysis of cultural milieus in 4 European countries (Estonia, Greece, Italy, and UK). The analysis is based on a questionnaire applied to a sample built through a two-step procedure of post-hoc random selection from a broader dataset based on an online survey. Responses to the questionnaire were subjected to multidimensional analysis-a combination of Multiple Correspondence Analysis and Cluster Analysis. We identified 5 symbolic universes, that correspond to basic, embodied, affect-laden, generalized worldviews. People in this study see the world as either a) an ordered universe; b) a matter of interpersonal bond; c) a caring society; d) consisting of a niche of belongingness; e) a hostile place (others' world). These symbolic universes were also interpreted as semiotic capital: they reflect the capacity of a place to foster social and civic development. Moreover, the distribution of the symbolic universes, and therefore social and civic engagement, is demonstrated to be variable across the 4 countries in the analysis. Finally, we develop a retrospective reconstruction of the distribution of symbolic universes as well as the interplay between their current state and past, present and future socio-institutional scenarios.

  13. Symbolic universes between present and future of Europe. First results of the map of European societies' cultural milieu

    Science.gov (United States)

    Fini, Viviana; Mannarini, Terri; Veltri, Giuseppe Alessandro; Avdi, Evrinomi; Battaglia, Fiorella; Castro-Tejerina, Jorge; Ciavolino, Enrico; Cremaschi, Marco; Kadianaki, Irini; Kharlamov, Nikita A.; Krasteva, Anna; Kullasepp, Katrin; Matsopoulos, Anastassios; Meschiari, Claudia; Mossi, Piergiorgio; Psinas, Polivios; Redd, Rozlyn; Rochira, Alessia; Santarpia, Alfonso; Sammut, Gordon; Valsiner, Jaan; Valmorbida, Antonella

    2018-01-01

    This paper reports the framework, method and main findings of an analysis of cultural milieus in 4 European countries (Estonia, Greece, Italy, and UK). The analysis is based on a questionnaire applied to a sample built through a two-step procedure of post-hoc random selection from a broader dataset based on an online survey. Responses to the questionnaire were subjected to multidimensional analysis–a combination of Multiple Correspondence Analysis and Cluster Analysis. We identified 5 symbolic universes, that correspond to basic, embodied, affect-laden, generalized worldviews. People in this study see the world as either a) an ordered universe; b) a matter of interpersonal bond; c) a caring society; d) consisting of a niche of belongingness; e) a hostile place (others’ world). These symbolic universes were also interpreted as semiotic capital: they reflect the capacity of a place to foster social and civic development. Moreover, the distribution of the symbolic universes, and therefore social and civic engagement, is demonstrated to be variable across the 4 countries in the analysis. Finally, we develop a retrospective reconstruction of the distribution of symbolic universes as well as the interplay between their current state and past, present and future socio-institutional scenarios. PMID:29298349

  14. English as a second language and outcomes of patients presenting with acute coronary syndromes: results from the CONCORDANCE registry.

    Science.gov (United States)

    Juergens, Craig P; Dabin, Bilyana; French, John K; Kritharides, Leonard; Hyun, Karice; Kilian, Jens; Chew, Derek Pb; Brieger, David

    2016-04-04

    To investigate whether patients with English as their second language have similar acute coronary syndrome (ACS) outcomes to people whose first language is English. Retrospective, observational study, using admissions, treatment and follow-up data. A total of 6304 subjects from 41 sites enrolled in the investigator-initiated CONCORDANCE ACS registry. Baseline characteristics, treatments, and in-hospital and 6-month mortality. English as a second language (ESL) was reported by 1005 subjects (15.9%). Patients with English as their first language (EFL) were older, and were less likely to have diabetes mellitus or to smoke than the ESL patients. Prior myocardial infarction, heart failure and chronic renal failure were more common in the ESL group. In-hospital mortality was also higher in these patients (7.1% v 3.8% for EFL patients; P language, age, in-hospital renal failure, and recurrent ischaemia as predictors of 6-month mortality. Patients presenting with an ACS who report English as their second language have poorer outcomes than patients who use English as their first language. This difference may not be entirely explained by baseline demographic disparities or management differences.

  15. Interim report - geotechnical site assessment methodology. Vol.1

    International Nuclear Information System (INIS)

    Tunbridge, L.W.; Richards, L.R.

    1983-05-01

    An interim report summarizing the research conducted on geotechnical site assessment methodology at the Carwynnen test mine in Cornwall. The geological setting of the test site in the Cornubian granite batholith is described. The effect of structure imposed by discontinuities on the engineering behaviour of rock masses is discussed and the scanline survey method of obtaining data on discontinuities in the rock mass is described. The requirement for remote geophysical methods of characterizing the mass is discussed and initial experiments using seismic and ultrasonic velocity measurements are reported. Computer programs to perform statistical analysis of the discontinuity patterns are described. Overcoring and hydraulic fracturing methods of determining the in-situ stress are briefly described and the results of a programme of in-situ stress measurements using the overcoring method are reported. (author)

  16. COCON: Corrosion research programme for long term interim storage conditions

    International Nuclear Information System (INIS)

    Desgranges, C.; Mazaudier, F.; Gauvain, D.; Terlain, A.; Feron, D.; Santarini, G.

    2003-01-01

    Two main corrosion phenomena are encountered in long term interim storage conditions: dry oxidation by the air when the temperature of high level nuclear wastes containers is high enough (roughly higher than 100 deg. C) and corrosion phenomena as those encountered in outdoor atmospheric corrosion when the temperature of the container wall is low enough and so condensation is possible on the container walls. Results obtained with dry oxidation in air lead to predict small damages (less than 1 μm on steels over 100 years at 100 deg. C) and no drastic changes with pollutants. For atmospheric corrosion, the first developments of a pragmatic method that gives assessments of the indoor atmospheric corrosivities are reported. (authors)

  17. Corrosion behaviour of metallic containers during long term interim storages

    International Nuclear Information System (INIS)

    Desgranges, C.; Feron, D.; Mazaudier, F.; Terlain, A.

    2001-01-01

    Two main corrosion phenomena are encountered in long term interim storage conditions: dry oxidation by the air when the temperature of high level nuclear wastes containers is high enough (roughly higher than 100 C) and corrosion phenomena as those encountered in outdoor atmospheric corrosion when the temperature of the container wall is low enough and so condensation is possible on the container walls. Results obtained with dry oxidation in air lead to predict small damages (less than 1μm on steels over 100 years at 100 C) and no drastic changes with pollutants. For atmospheric corrosion, first developments deal with a pragmatic method that gives assessments of the indoor atmospheric corrosivities. (author)

  18. Present situation and prospect of medical knowledge based systems in German-speaking countries: results of an online survey.

    Science.gov (United States)

    Spreckelsen, Cord; Spitzer, K; Honekamp, W

    2012-01-01

    After a decrease of interest in classical medical expert systems, the publication activity concerning the medical application of Artificial Intelligence and the interest in medical decision support have markedly increased. Nonetheless, no systematic exploratory study has yet been carried out, which directly considers the actual fields of applications, exemplary approaches, obstacles, challenges, and future prospect as seen by pioneering users and developers in a given region. This paper reports the results of an online survey designed to fill this gap with the "Knowledge Based Systems" working group of the German Society for Medical Informatics, Biometry and Epidemiology (GMDS) in 2010. The survey was based on an online questionnaire (5 single and multiple choice questions, 8 Likert-scaled items, 7 free text questions) consented to by the working group. The answers were analyzed by descriptive statistics and a qualitative analysis (bottom-up coding). All academic institutions of Medical Informatics in the German-speaking countries and contributors reporting KBS-related projects at the relevant scientific conferences and in a journal specialized in the field were invited to participate. The survey reached a response rate of 33.4%. The results show a gap between the reported obstacles of medical KBS (mainly low acceptance and rare use in clinical practice) and their future prospect as stated by the participants. Problems previously discussed in the literature like low acceptance, integration, and sustainability of KBS projects were confirmed. The current situation was characterized by naming exemplary existing systems and specifying promising fields of application. The field of KBS in medicine is more diversified and has evolved beyond expectations in the German-speaking countries.

  19. ICPP radioactive liquid and calcine waste technologies evaluation. Interim report

    Energy Technology Data Exchange (ETDEWEB)

    Murphy, J.A.; Pincock, L.F.; Christiansen, I.N.

    1994-06-01

    The Department of Energy (DOE) has received spent nuclear fuel (SNF) at the Idaho Chemical Processing Plant (ICPP) for interim storage since 1951 and reprocessing since 1953. Until recently, the major activity of the ICPP has been the reprocessing of SNF to recover fissile uranium; however, changing world events have raised questions concerning the need to recover and recycle this material. In April 1992, DOE chose to discontinue reprocessing SNF for uranium recovery and shifted its focus toward the management and disposition of radioactive wastes accumulated through reprocessing activities. Currently, 1.8 million gallons of radioactive liquid wastes (1.5 million gallons of radioactive sodium-bearing liquid wastes and 0.3 million gallons of high-level liquid waste) and 3,800 cubic meters (m{sup 3}) of calcine waste are in inventory at the ICPP. Legal drivers and agreements exist obligating the INEL to develop, demonstrate, and implement technologies for safe and environmentally sound treatment and interim storage of radioactive liquid and calcine waste. Candidate treatment processes and waste forms are being evaluated using the Technology Evaluation and Analysis Methodology (TEAM) Model. This process allows decision makers to (1) identify optimum radioactive waste treatment and disposal form alternatives; (2) assess tradeoffs between various optimization criteria; (3) identify uncertainties in performance parameters; and (4) focus development efforts on options that best satisfy stakeholder concerns. The Systems Analysis technology evaluation presented in this document supports the DOE in selecting the most effective radioactive liquid and calcine waste management plan to implement in compliance with established regulations, court orders, and agreements.

  20. The challenges facing the long term interim storage

    International Nuclear Information System (INIS)

    Iracane, D.; Marvy, A.

    2001-01-01

    In France electricity generation by means of commercial nuclear power plants has come to a point where it contributes to the national demand at a level of 80%. The safety performance of the production system has also reached a high level of both maturity and reliability taking advantage of the cumulative effect of a 30 years long learning experience and ever more stringent safety requirements. The policy to reprocess spent fuel has been overriding but no final decision has yet been made regarding the ultimate disposition of the waste streams. Although studies on deep geological disposal are ongoing, France is also looking at whether and under which conditions a long-term interim storage may provide an effective flexibility to the fuel cycle back-end. We discuss thereafter the needs and the paramount objectives of this latter R and D program. Results are being framed as potential guiding criteria for decision makers and various stakeholders. In first part, we propose a general analysis which emphasises that a long term interim storage is more than a classical nuclear facility because it explicitly requires long-lasting control and creates a burden for Society during many generations. Then, in second part, we offer an overview of the technical results from the R and D program as they stand at the time of writing. As an answer to the Government request, a strong emphasis has been put on this research for three years. Conclusion is an attempt to outline the societal context in which future decisions will have to be made. (author)

  1. Presentation and surgical results of incidentally discovered nonfunctioning pituitary adenomas: evidence for a better outcome independently of other patients' characteristics.

    Science.gov (United States)

    Losa, Marco; Donofrio, Carmine A; Barzaghi, Raffaella; Mortini, Pietro

    2013-12-01

    Few data are available on the surgical results in patients with incidentally discovered nonfunctioning pituitary adenoma (NFPA). We investigated the efficacy and safety of surgery in patients with incidentally discovered NFPA. Retrospective analysis of prospectively recorded outcomes. From 1990 to 2011, of 804 consecutive patients undergoing surgery for NFPA, 212 cases had an incidentally discovered tumor (26.4%). Among them, 117 patients were asymptomatic, while 95 had some visual and/or hormonal deficit. The main outcome of the study was to evaluate the frequency of radical resection as judged on the first postoperative neuroimaging study and detection of recurring disease during long-term follow-up. Postoperative residual tumor was detected in 8.9% of patients with asymptomatic incidentalomas as compared with 31.2% of patients with symptomatic incidentalomas (P<0.001) and 41.2% of patients in the control group (P<0.001). Multivariate analysis confirmed that having an asymptomatic incidentaloma was independently associated with a better outcome. The 5-year recurrence-free survival in patients with incidentaloma was 86.8% (95% CI 80.2-92.4%) as compared with 77.9% (95% CI 73.6-82.2%; P<0.01) in the control group. This difference was almost completely due to a lower frequency of relapse in asymptomatic patients. Multivariate analysis confirmed the independent lower risk of tumor recurrence in asymptomatic NFPA. Our study shows for the first time that surgically treated patients with asymptomatic NFPA have a better early and long-term outcome that is independent from all the other demographic, clinical, and morphologic characteristics of the patients.

  2. Presentation of the results of 1993-1994 of the peat production research area; Turvetuotanto - tutkimusalueen katsaus

    Energy Technology Data Exchange (ETDEWEB)

    Leinonen, A.

    1996-12-31

    The development target of the peat production research area of the Biomass research programme is to improve the competitivity of peat by reducing the production costs by 20 % (5-6 FIM/MWh) from the level of 1992 and to reduce the environmental load. The main targets of peat production, by which the target can be met, are ditching and preparation technologies, drying technology, machine technology, methodology, integration of wood harvesting and peat production, and application of the results of the Optimiturve research programme in practice. The objectives of the peat production research are possible to meet if the partial targets are met. Increment of the open-ditch distance from 20 m to 60 m reduces the production costs by 5.0 %, increment of the rate of utilization of solar radiation from 30 % to 40 % reduces the production costs by 8 %, reduction of the amount of residual peat from 3000 MWh to 1500 MWh reduces the costs by 6.5 %, development of light and firesafe machines by 3 %, and integrated harvesting of wood by 3 %. Meeting of the partial targets reduces the production costs by 24 %. The main research areas of peat production will be carried out further. The total funding of the peat production researches in 1993-1994 was 19.4 million FIM (9.7 million FIM/a). The share of the total funding of the research organization projects has been 6.7 million FIM and that of the company projects 12.7 million FIM. The share of the Finnish Ministry of Trade and Industry of the funding has been 9.0 million FIM (46 %)

  3. 1998 interim 242-A Evaporator tank system integrity assessment report

    Energy Technology Data Exchange (ETDEWEB)

    Jensen, C.E.

    1998-07-02

    This Integrity Assessment Report (IAR) is prepared by Fluor Daniel Northwest (FDNW) under contract to Lockheed-Martin Hanford Company (LMHC) for Waste Management Hanford (WMH), the 242-A Evaporator (facility) operations contractor for Fluor Daniel Hanford, and the US Department of Energy, the system owner. The contract specifies that FDNW perform an interim (5 year) integrity assessment of the facility and prepare a written IAR in accordance with Washington Administrative Code (WAC) 173-303-640. The WAC 173-303 defines a treatment, storage, or disposal (TSD) facility tank system as the ``dangerous waste storage or treatment tank and its ancillary equipment and containment.`` This integrity assessment evaluates the two tank systems at the facility: the evaporator vessel, C-A-1 (also called the vapor-liquid separator), and the condensate collection tank, TK-C-100. This IAR evaluates the 242-A facility tank systems up to, but not including, the last valve or flanged connection inside the facility perimeter. The initial integrity assessment performed on the facility evaluated certain subsystems not directly in contact with dangerous waste, such as the steam condensate and used raw water subsystems, to provide technical information. These subsystems were not evaluated in this IAR. The last major upgrade to the facility was project B-534. The facility modifications, as a result of project B-534, were evaluated in the 1993 facility interim integrity assessment. Since that time, the following upgrades have occurred in the facility: installation of a process condensate recycle system, and installation of a package steam boiler to provide steam for the facility. The package boiler is not within the scope of the facility TSD.

  4. Interim action record of decision remedial alternative selection: TNX area groundwater operable unit

    International Nuclear Information System (INIS)

    Palmer, E.R.

    1994-10-01

    This document presents the selected interim remedial action for the TNX Area Groundwater Operable Unit at the Savannah River Site (SRS), which was developed in accordance with CERCLA of 1980, as amended by the Superfund Amendments and Reauthorization Act (SARA) of 1986, and to the extent practicable, the National Oil and Hazardous Substances Pollution contingency Plan (NCP). This decision is based on the Administrative Record File for this specific CERCLA unit

  5. PROJECT W-551 INTERIM PRETREATMENT SYSTEM PRECONCEPTUAL CANDIDATE TECHNOLOGY DESCRIPTIONS

    Energy Technology Data Exchange (ETDEWEB)

    MAY TH

    2008-08-12

    The Office of River Protection (ORP) has authorized a study to recommend and select options for interim pretreatment of tank waste and support Waste Treatment Plant (WTP) low activity waste (LAW) operations prior to startup of all the WTP facilities. The Interim Pretreatment System (IPS) is to be a moderately sized system which separates entrained solids and 137Cs from tank waste for an interim time period while WTP high level waste vitrification and pretreatment facilities are completed. This study's objective is to prepare pre-conceptual technology descriptions that expand the technical detail for selected solid and cesium separation technologies. This revision includes information on additional feed tanks.

  6. Development of a unit cell model for interim performance assessment of vitrified low level waste disposal

    International Nuclear Information System (INIS)

    Kline, N.W.

    1995-09-01

    The unit cell modeling approach has been developed and used in analysis of some design options for a vitrified low level waste disposal facility. The unit cell modeling approach is likely to be useful in interim performance assessment for the facility. The present unit cell model will probably need to be refitted in terms of some model parameters for the latter purpose. Two present disposal facility concepts differ in the length of a capillary barrier proposed to limit effective recharge through the top of the facility. Results of the study summarized herein suggest design of a capillary barrier which can reduce a recharge rate of 0.1 cm/yr by one or two orders of magnitude seems feasible for both concepts. A benchmark comparison of the unit cell model against a full facility model shows comparable predictive accuracy in less than one percent of the computer time. Results suggest that model parameters include capillary barrier performance, inter-canister spacing, rate of moisture withdrawal due to glass corrosion, contaminant inventory, and the well interceptor factor. It is also important that variations of waste form hydraulic parameters suggest that transport through the waste form is dominated by diffusion

  7. Interim report on the feasibility study of acoustic leak location for WTD steam generators. [LMFBR

    Energy Technology Data Exchange (ETDEWEB)

    Greene, D.A.; McMurtrie, K.A.

    1979-03-01

    This interim report summarizes the current status of a feasibility study of an acoustic leak location system for two Westinghouse-Tampa Division (WTD) double-wall steam generators. The primary WTD design requirement is that a leak of helium gas into sodium be located to within a cluster of seven tubes at hot standby conditions. The report documents the results of an extensive analytical assessment, outlines areas of concern resulting from the analyses which will require experimental validation, and presents results of experiments thus far completed. The conclusion of the study at this time is that acoustic leak location is feasible, pending the results of the remaining experimental tests. The acoustic leak location system operates on the same principles as the acoustic leak detection system being developed under SG027, Subtask X2. Analyses indicate that, in general, the location system will use similar design parameters to the acoustic leak detection system. Much of the hardware can be indentical, in particular the accelerometers. It is recommended that a minicomputer/software approach be employed rather than the custom-designed hardware approach used for the detection system.

  8. Payment charges for federal interim storage of spent nuclear fuel from civilian nuclear power plants in the United States

    International Nuclear Information System (INIS)

    1983-07-01

    This report describes the study conducted by the Department of Energy (the Department) regarding payment charges for the federal interim storage (FIS) of spent fuel and presents the study results. It describes the methodology proposed for calculating the FIS fee schedule, provides a range of estimates for the fee, and describes a proposed method of payment. The fee is structured for a range of spent fuel capacities because of uncertainties regarding the schedule of availability and amount of spent fuel that may require and qualify for FIS. The Department is currently determining how best to provide FIS for commercial spent fuel, and it expects to publish in the Federal Register a fee schedule to be effective on or before January 1, 1984. An additional report to Congress describing specific plans for deploying FIS facilities will be provided by January 7, 1984, in accordance with the requirements of the Act. 3 references, 3 tables

  9. Approaches to interim analysis of cancer randomised clinical trials with time to event endpoints: A survey from the Italian National Monitoring Centre for Clinical Trials

    Directory of Open Access Journals (Sweden)

    De Rosa Marisa

    2008-07-01

    Full Text Available Abstract Background Although interim analysis approaches in clinical trials are widely known, information on current practice of planned monitoring is still scarce. Reports of studies rarely include details on the strategies for both data monitoring and interim analysis. The aim of this project is to investigate the forms of monitoring used in cancer clinical trials and in particular to gather information on the role of interim analyses in the data monitoring process of a clinical trial. This study focused on the prevalence of different types of interim analyses and data monitoring in cancer clinical trials. Methods Source of investigation were the protocols of cancer clinical trials included in the Italian registry of clinical trials from 2000 to 2005. Evaluation was restricted to protocols of randomised studies with a time to event endpoint, such as overall survival (OS or progression free survival (PFS. A template data extraction form was developed and tested in a pilot phase. Selection of relevant protocols and data extraction were performed independently by two evaluators, with differences in the data assessment resolved by consensus with a third reviewer, referring back to the original protocol. Information was obtained on a general characteristics of the protocol b disease localization and patient setting; c study design d interim analyses; e DSMC. Results The analysis of the collected protocols reveals that 70.7% of the protocols incorporate statistical interim analysis plans, but only 56% have also a DSMC and be considered adequately planned. The most concerning cases are related to lack of any form of monitoring (20.0% of the protocols, and the planning of interim analysis, without DSMC (14.7%. Conclusion The results indicate that there is still insufficient attention paid to the implementation of interim analysis.

  10. ISOE EG-SAM interim report - Report on behalf of the Sub expert Group

    International Nuclear Information System (INIS)

    Harris, Willie; Miller, David W.; Djeffal, Salah; Anderson, Ellen; Couasnon, Olivier; Hagemeyer, Derek; Sovijarvi, Jukka; Amaral, Marcos A.; Tarzia, J.P.; Schmidt, Claudia; Fritioff, Karin; Kaulard, Joerg; Lance, Benoit; Fritioff, Karin; Schieber, Caroline; Hayashida, Yoshihisa; Doty, Rick

    2014-01-01

    During its November 2012 meeting, the expert group decided to develop an interim (preliminary) report before the end of 2013 (with a general perspective and discussion of specific severe accident management worker dose issues), and to finalize the report by organizing the international workshop of 2014 to address national experiences, which will be incorporated to the report. The work of the EG-SAM focuses on radiation protection management and organization, radiation protection training and exercises related to severe accident management, facility configuration and readiness, worker protection, radioactive materials, contamination controls and logistics and key lessons learned especially from the TMI, Chernobyl and Fukushima Dai-ichi accidents. This interim report was completed through intensive work of all Group members nominated by the ISOE, and was accomplished during EG-SAM meetings through 2012-2013. This document gathers the different presentations given by the sub expert groups in charge of each chapter of the report

  11. Value of information: interim analysis of a randomized, controlled trial of goal-directed hemodynamic treatment for aged patients.

    Science.gov (United States)

    Bartha, Erzsebet; Davidson, Thomas; Brodtkorb, Thor-Henrik; Carlsson, Per; Kalman, Sigridur

    2013-07-09

    A randomized, controlled trial, intended to include 460 patients, is currently studying peroperative goal-directed hemodynamic treatment (GDHT) of aged hip-fracture patients. Interim efficacy analysis performed on the first 100 patients was statistically uncertain; thus, the trial is continuing in accordance with the trial protocol. This raised the present investigation's main question: Is it reasonable to continue to fund the trial to decrease uncertainty? To answer this question, a previously developed probabilistic cost-effectiveness model was used. That model depicts (1) a choice between routine fluid treatment and GDHT, given uncertainty of current evidence and (2) the monetary value of further data collection to decrease uncertainty. This monetary value, that is, the expected value of perfect information (EVPI), could be used to compare future research costs. Thus, the primary aim of the present investigation was to analyze EVPI of an ongoing trial with interim efficacy observed. A previously developed probabilistic decision analytic cost-effectiveness model was employed to compare the routine fluid treatment to GDHT. Results from the interim analysis, published trials, the meta-analysis, and the registry data were used as model inputs. EVPI was predicted using (1) combined uncertainty of model inputs; (2) threshold value of society's willingness to pay for one, quality-adjusted life-year; and (3) estimated number of future patients exposed to choice between GDHT and routine fluid treatment during the expected lifetime of GDHT. If a decision to use GDHT were based on cost-effectiveness, then the decision would have a substantial degree of uncertainty. Assuming a 5-year lifetime of GDHT in clinical practice, the number of patients who would be subject to future decisions was 30,400. EVPI per patient would be €204 at a €20,000 threshold value of society's willingness to pay for one quality-adjusted life-year. Given a future population of 30,400 individuals

  12. Interim Feed The Future Population Based Assessment of Cambodia

    Data.gov (United States)

    US Agency for International Development — This is the interim population based survey of Feed the Future in Cambodia for 2015. The data is split into survey modules. Modules A through C includes location...

  13. Fire Hazards Analysis for the 200 Area Interim Storage Area

    International Nuclear Information System (INIS)

    JOHNSON, D.M.

    2000-01-01

    This documents the Fire Hazards Analysis (FHA) for the 200 Area Interim Storage Area. The Interim Storage Cask, Rad-Vault, and NAC-1 Cask are analyzed for fire hazards and the 200 Area Interim Storage Area is assessed according to HNF-PRO-350 and the objectives of DOE Order 5480 7A. This FHA addresses the potential fire hazards associated with the Interim Storage Area (ISA) facility in accordance with the requirements of DOE Order 5480 7A. It is intended to assess the risk from fire to ensure there are no undue fire hazards to site personnel and the public and to ensure property damage potential from fire is within acceptable limits. This FHA will be in the form of a graded approach commensurate with the complexity of the structure or area and the associated fire hazards

  14. Computerization of material test data reporting system : interim report.

    Science.gov (United States)

    1973-09-01

    This study was initiated to provide an integrated system of reporting, storing, and retrieving of construction and material test data using computerized (storage-retrieval) and quality control techniques. The findings reported in this interim report ...

  15. 14 CFR 136.41 - Interim operating authority.

    Science.gov (United States)

    2010-01-01

    ... tribal lands. (2) ATMP limitation. The Administrator may grant interim operating authority under this paragraph (c) only if the ATMP for the park or tribal lands to which the application relates has not been...

  16. TANK FARM INTERIM SURFACE BARRIER MATERIALS AND RUNOFF ALTERNATIVES STUDY

    Energy Technology Data Exchange (ETDEWEB)

    HOLM MJ

    2009-06-25

    This report identifies candidate materials and concepts for interim surface barriers in the single-shell tank farms. An analysis of these materials for application to the TY tank farm is also provided.

  17. Interim research assessment 2003-2005 - Computer Science

    NARCIS (Netherlands)

    Mouthaan, A.J.; Hartel, Pieter H.

    This report primarily serves as a source of information for the 2007 Interim Research Assessment Committee for Computer Science at the three technical universities in the Netherlands. The report also provides information for others interested in our research activities.

  18. Tank Farm Interim Surface Barrier Materials And Runoff Alternatives Study

    International Nuclear Information System (INIS)

    Holm, M.J.

    2009-01-01

    This report identifies candidate materials and concepts for interim surface barriers in the single-shell tank farms. An analysis of these materials for application to the TY tank farm is also provided.

  19. An Experimental Seismic Data and Parameter Exchange System for Interim NEAMTWS

    Science.gov (United States)

    Hanka, W.; Hoffmann, T.; Weber, B.; Heinloo, A.; Hoffmann, M.; Müller-Wrana, T.; Saul, J.

    2009-04-01

    In 2008 GFZ Potsdam has started to operate its global earthquake monitoring system as an experimental seismic background data centre for the interim NEAMTWS (NE Atlantic and Mediterranean Tsunami Warning System). The SeisComP3 (SC3) software, developed within the GITEWS (German Indian Ocean Tsunami Early Warning System) project was extended to test the export and import of individual processing results within a cluster of SC3 systems. The initiated NEAMTWS SC3 cluster consists presently of the 24/7 seismic services at IMP, IGN, LDG/EMSC and KOERI, whereas INGV and NOA are still pending. The GFZ virtual real-time seismic network (GEOFON Extended Virtual Network - GEVN) was substantially extended by many stations from Western European countries optimizing the station distribution for NEAMTWS purposes. To amend the public seismic network (VEBSN - Virtual European Broadband Seismic Network) some attached centres provided additional private stations for NEAMTWS usage. In parallel to the data collection by Internet the GFZ VSAT hub for the secured data collection of the EuroMED GEOFON and NEAMTWS backbone network stations became operational and the first data links were established. In 2008 the experimental system could already prove its performance since a number of relevant earthquakes have happened in NEAMTWS area. The results are very promising in terms of speed as the automatic alerts (reliable solutions based on a minimum of 25 stations and disseminated by emails and SMS) were issued between 2 1/2 and 4 minutes for Greece and 5 minutes for Iceland. They are also promising in terms of accuracy since epicenter coordinates, depth and magnitude estimates were sufficiently accurate from the very beginning, usually don't differ substantially from the final solutions and provide a good starting point for the operations of the interim NEAMTWS. However, although an automatic seismic system is a good first step, 24/7 manned RTWCs are mandatory for regular manual verification

  20. Interim Safety Basis for Fuel Supply Shutdown Facility

    Energy Technology Data Exchange (ETDEWEB)

    BENECKE, M.W.

    2000-09-07

    This ISB, in conjunction with the IOSR, provides the required basis for interim operation or restrictions on interim operations and administrative controls for the facility until a SAR is prepared in accordance with the new requirements or the facility is shut down. It is concluded that the risks associated with tha current and anticipated mode of the facility, uranium disposition, clean up, and transition activities required for permanent closure, are within risk guidelines.

  1. Interim Safety Basis for Fuel Supply Shutdown Facility

    International Nuclear Information System (INIS)

    BENECKE, M.W.

    2000-01-01

    This ISB, in conjunction with the IOSR, provides the required basis for interim operation or restrictions on interim operations and administrative controls for the facility until a SAR is prepared in accordance with the new requirements or the facility is shut down. It is concluded that the risks associated with tha current and anticipated mode of the facility, uranium disposition, clean up, and transition activities required for permanent closure, are within risk guidelines

  2. ITER interim design report package and relevant documents

    International Nuclear Information System (INIS)

    1996-01-01

    This publication documents the technical basis which underlay the Interim Design Report, Cost Review and Safety Analysis submitted to the ITER Councils (IC-8 and IC-9) Records of decisions and the ''ITER Interim Design Report Package''. This publication contains ITER Site Requirements and ITER Site Design Assumptions, TAC-8 Report, SRG Report, CP's Report on Tentative Sequence of Events and Parties' Views on the IDR Package and Parties' Technical Comments on the IDR Package. Figs, tabs

  3. K basins interim remedial action health and safety plan

    Energy Technology Data Exchange (ETDEWEB)

    DAY, P.T.

    1999-09-14

    The K Basins Interim Remedial Action Health and Safety Plan addresses the requirements of the Comprehensive Environmental Response, Compensation and Liability Act (CERCLA), as they apply to the CERCLA work that will take place at the K East and K West Basins. The provisions of this plan become effective on the date the US Environmental Protection Agency issues the Record of Decision for the K Basins Interim Remedial Action, currently planned in late August 1999.

  4. Improving Ventilation and Saving Energy: Relocatable ClassroomField Study Interim Report

    Energy Technology Data Exchange (ETDEWEB)

    Apte, Michael G.; Buchanan, Ian S.; Faulkner, David; Hotchi,Toshifumi; Spears,Michael; Sullivan, Douglas P.; Wang, Duo

    2005-09-01

    The primary goals of this research effort are to develop, evaluate, and demonstrate a very practical HVAC system for classrooms that consistently provides classrooms with the quantity of ventilation in current minimum standards, while saving energy, and reducing HVAC-related noise levels. This research is motivated by the public benefits of energy efficiency, evidence that many classrooms are under-ventilated, and public concerns about indoor environmental quality in classrooms. This report presents an interim status update and preliminary findings from energy and indoor environmental quality (IEQ) measurements in sixteen relocatable classrooms in California. The field study includes measurements of HVAC energy use, ventilation rates, and IEQ conditions. Ten of the classrooms were equipped with a new HVAC technology and six control classrooms were equipped with a standard HVAC system. Energy use and many IEQ parameters have been monitored continuously, while unoccupied acoustic measurements were measured in one of four planned seasonal measurement campaigns. Continuously monitored data are remotely accessed via a LonWorks{reg_sign} network and stored in a relational database at LBNL. Preliminary results are presented here.

  5. Hydrogeology of the 200 Areas low-level burial grounds: An interim report: Volume 1, Text

    Energy Technology Data Exchange (ETDEWEB)

    Last, G.V.; Bjornstad, B.N.; Bergeron, M.P.; Wallace, D.W.; Newcomer, D.R.; Schramke, J.A.; Chamness, M.A.; Cline, C.S.; Airhart, S.P.; Wilbur, J.S.

    1989-01-01

    This report presents information derived from the installation of 35 ground-water monitoring wells around six low-level radioactive/hazardous waste burial grounds located in the 200 Areas of the Hanford Site in southeastern Washington State. This information was collected between May 20, 1987 and August 1, 1988. The contents of this report have been divided into two volumes. This volume contains the main text. Volume 2 contains the appendixes, including data and supporting information that verify content and results found in the main text. This report documents information collected by the Pacific Northwest Laboratory at the request of Westinghouse Hanford Company. Presented in this report are the preliminary interpretations of the hydrogeologic environment of six low-level burial grounds, which comprise four waste management areas (WMAs) located in the 200 Areas of the Hanford Site. This information and its accompanying interpretations were derived from sampling and testing activities associated with the construction of 35 ground-water monitoring wells as well as a multitude of previously existing boreholes. The new monitoring wells were installed as part of a ground-water monitoring program initiated in 1986. This ground-water monitoring program is based on requirements for interim status facilities in compliance with the Resource Conservation and Recovery Act (1976).

  6. The Time Needed to Implement the Blue Ribbon Commission Recommendation on Interim Storage - 13124

    International Nuclear Information System (INIS)

    Voegele, Michael D.; Vieth, Donald

    2013-01-01

    The report of the Blue Ribbon Commission on America's Nuclear Future [1] makes a number of important recommendations to be considered if Congress elects to redirect U.S. high-level radioactive waste disposal policy. Setting aside for the purposes of this discussion any issues related to political forces leading to stopping progress on the Yucca Mountain project and driving the creation of the Commission, an important recommendation of the Commission was to institute prompt efforts to develop one or more consolidated storage facilities. The Blue Ribbon Commission noted that this recommended strategy for future storage and disposal facilities and operations should be implemented regardless of what happens with Yucca Mountain. It is too easy, however, to focus on interim storage as an alternative to geologic disposal. The Blue Ribbon Commission report does not go far enough in addressing the magnitude of the contentious problems associated with reopening the issues of relative authorities of the states and federal government with which Congress wrestled in crafting the Nuclear Waste Policy Act [2]. The Blue Ribbon Commission recommendation for prompt adoption of an interim storage program does not appear to be fully informed about the actions that must be taken, the relative cost of the effort, or the realistic time line that would be involved. In essence, the recommendation leaves to others the details of the systems engineering analyses needed to understand the nature and details of all the operations required to reach an operational interim storage facility without derailing forever the true end goal of geologic disposal. The material presented identifies a number of impediments that must be overcome before the country could develop a centralized federal interim storage facility. In summary, and in the order presented, they are: 1. Change the law, HJR 87, PL 107-200, designating Yucca Mountain for the development of a repository. 2. Bring new nuclear waste

  7. Immobilized low-activity waste interim storage facility, Project W-465 conceptual design report

    International Nuclear Information System (INIS)

    Pickett, W.W.

    1997-01-01

    This report outlines the design and Total Estimated Cost to modify the four unused grout vaults for the remote handling and interim storage of immobilized low-activity waste (ILAW). The grout vault facilities in the 200 East Area of the Hanford Site were constructed in the 1980s to support Tank Waste disposal activities. The facilities were to serve project B-714 which was intended to store grouted low-activity waste. The existing 4 unused grout vaults, with modifications for remote handling capability, will provide sufficient capacity for approximately three years of immobilized low activity waste (ILAW) production from the Tank Waste Remediation System-Privatization Vendors (TWRS-PV). These retrofit modifications to the grout vaults will result in an ILAW interim storage facility (Project W465) that will comply with applicable DOE directives, and state and federal regulations

  8. Safety evaluation of interim stabilization of non-stabilized single-shell watch list tanks

    International Nuclear Information System (INIS)

    Stahl, S.M.

    1994-01-01

    This report provides results of a review of recently completed safety analyses related to hazards associated with Interim Stabilization of Single analyses related to hazards included oh the Hanford Site Waste Tank-Watch Shell Tanks (SSTs) that are included on the Hanford List. The purpose of the review was to identify and summarize conclusions regarding the safety of interim stabilization of Watch List SSTs, and to highlight applicable limitations, restrictions, and controls. The scope of this review was restricted to SSTs identified List in the categories of flammable gas ferrocyanide, and organic salts. High heat tanks were not included in the scope. A Watch List tank is defined as an underground storage tank containing waste that requires special safety precautions because it may have a serious potential for release of high level radioactive waste because of uncontrolled increases in temperature or pressure. Special restrictions have been placed on these tanks

  9. Second interim assessment of the Canadian concept for nuclear fuel waste disposal. Volume 1

    International Nuclear Information System (INIS)

    Wuschke, D.M.; Gillespie, P.A.; Main, D.E.

    1985-07-01

    The nuclear fuel waste disposal concept chosen for development and assessment in Canada involves the isolation of corrosion-resistant containers of waste in a vault located deep in plutonic rock. As the concept and the assessment tools are developed, periodic assessments are performed to permit evaluation of the methodology and provide feedback to those developing the concept. The ultimate goal of these assessments is to predict what impact the disposal system would have on man and the environment if the concept were implemented. The second assessment was performed in 1984 and is documented in the Second Interim assessment of the Canadian Concept for Nuclear Fuel Waste Disposal Volumes 1 to 4. This volume, entitled Summary, is a condensation of Volumes 2, 3 and 4. It briefly describes the Canadian nuclear fuel waste disposal concept, and the methods and results of the second interim pre-closure and post-closure assessments of that concept. 46 refs

  10. Immobilized low-activity waste interim storage facility, Project W-465 conceptual design report

    Energy Technology Data Exchange (ETDEWEB)

    Pickett, W.W.

    1997-12-30

    This report outlines the design and Total Estimated Cost to modify the four unused grout vaults for the remote handling and interim storage of immobilized low-activity waste (ILAW). The grout vault facilities in the 200 East Area of the Hanford Site were constructed in the 1980s to support Tank Waste disposal activities. The facilities were to serve project B-714 which was intended to store grouted low-activity waste. The existing 4 unused grout vaults, with modifications for remote handling capability, will provide sufficient capacity for approximately three years of immobilized low activity waste (ILAW) production from the Tank Waste Remediation System-Privatization Vendors (TWRS-PV). These retrofit modifications to the grout vaults will result in an ILAW interim storage facility (Project W465) that will comply with applicable DOE directives, and state and federal regulations.

  11. Criticality safety evaluation for long term storage of FFTF fuel in interim storage casks

    International Nuclear Information System (INIS)

    Richard, R.F.

    1995-01-01

    It has been postulated that a degradation phenomenon, referred to as ''hot cell rot'', may affect irradiated FFTF mixed plutonium-uranium oxide (MOX) fuel during dry interim storage. ''Hot cell rot'' refers to a variety of phenomena that degrade fuel pin cladding during exposure to air and inert gas environments. It is thought to be a form of caustic stress corrosion cracking or environmentally assisted cracking. Here, a criticality safety analysis was performed to address the effect of the ''hot cell rot'' phenomenon on the long term storage of irradiated FFTF fuel in core component containers. The results show that seven FFTF fuel assemblies or six Ident-69 pin containers stored in core component containers within interim storage casks will remain safely subcritical

  12. Probabilistic Assessment Method of Turbojet Engine Impact on an Interim Dry Storage Facility

    Energy Technology Data Exchange (ETDEWEB)

    Almomania, Belal; Kang, Hyun Gook [KAIST, Daejeon (Korea, Republic of); Lee, Sang Hoon [Keimyung University, Daegu (Korea, Republic of)

    2016-05-15

    This paper describes an analytical method of structural analysis for an interim storage facility subjected to aircraft jet engine based on a probabilistic approach. This method will be employed in the process of aircraft risk model for the interim storage facilities. The analytical formulation of the engine impact and the perforation to find the required thickness of concrete to protect the equipment inside the structure is an enormously complex impact phenomenon. Therefore, all the available formulas describing perforation phenomena are empirical and based on experimental data. In this paper, a method with sample results to determine the local failure probability of the facility's wall and the probable residual velocities after passed through the target by applying a probabilistic approach was proposed. Normal engine impact on the wall shield using applicable empirical formulas provides a best estimation of perforation depth and residual velocity with intent of producing conservative outcomes.

  13. Interim summary report of the safety case 2009

    International Nuclear Information System (INIS)

    2010-03-01

    Following the guidelines set forth by the Ministry of Trade and Industry (now Ministry of Employment and Economy), Posiva is preparing to submit a construction license application for the final disposal spent nuclear fuel at the Olkiluoto site, Finland, by the end of the year 2012. Disposal will take place in a geological repository implemented according to the KBS-3 method. The long-term safety section supporting the license application will be based on a safety case that, according to the internationally adopted definition, will be a compilation of the evidence, analyses and arguments that quantify and substantiate the safety and the level of expert confidence in the safety of the planned repository. The present Interim Summary Report represents a major contribution to the development of this safety case. The report has been compiled in accordance with Posiva's current plan for preparing this safety case. A full safety case for the KBS-3V variant will be developed to support the Preliminary Safety Assessment Report (PSAR) in 2012. The report outlines the current design and safety concept for the planned repository. It summarises the approach used to formulate scenarios for the evolution of the disposal system over time, describes these scenarios and presents the main models and computer codes used to analyse them. It also discusses compliance with Finnish regulatory requirements for long-term safety of a geological repository and gives the main evidence, arguments and analyses that lead to confidence, on the part of Posiva, in the long-term safety of the planned repository. Current understanding of the evolution of the disposal system indicates that, except a few unlikely circumstances affecting a small number of canisters, spent fuel will remain isolated, and the radionuclides contained within the canisters, for hundreds of thousands of years or more, in accordance with the base scenario. Confidence in this base scenario derives, in the first place, from the

  14. Lessons learned from the Siting Process of an Interim Storage Facility in Spain - 12024

    Energy Technology Data Exchange (ETDEWEB)

    Lamolla, Meritxell Martell [MERIENCE Strategic Thinking, 08734 Olerdola, Barcelona (Spain)

    2012-07-01

    On 29 December 2009, the Spanish government launched a site selection process to host a centralised interim storage facility for spent fuel and high-level radioactive waste. It was an unprecedented call for voluntarism among Spanish municipalities to site a controversial facility. Two nuclear municipalities, amongst a total of thirteen municipalities from five different regions, presented their candidatures to host the facility in their territories. For two years the government did not make a decision. Only in November 30, 2011, the new government elected on 20 November 2011 officially selected a non-nuclear municipality, Villar de Canas, for hosting this facility. This paper focuses on analysing the factors facilitating and hindering the siting of controversial facilities, in particular the interim storage facility in Spain. It demonstrates that involving all stakeholders in the decision-making process should not be underestimated. In the case of Spain, all regional governments where there were candidate municipalities willing to host the centralised interim storage facility, publicly opposed to the siting of the facility. (author)

  15. Conceptual design of interim storage facility for CNAI

    International Nuclear Information System (INIS)

    Fuenzalida Troyano, Carlos S.; Bergallo, Juan E.; Nassini, Horacio E.P.; Blanco, Anibal; Delmastro, Dario F.

    2007-01-01

    The reduced storage capacity available in the two spent fuel pools of argentine PHWR Atucha-1 power plant, the current plans for extending the reactor operation beyond its design lifetime, and the government decision on Atucha-2 NPP construction ending, have motivated the evaluation of a dry storage option for the interim management of spent fuel assemblies. Two different designs are presently being analyzed by an expert working group, from both technical and economical points of views. Authors are proposing a modular system consisting of an arrangement of reinforced concrete structures into which welded metallic canisters loaded with 37 spent fuel assemblies each stored in horizontal position. The reinforced concrete module is designed to provide the necessary physical protection and biological shielding to the loaded canisters during long-term storage, as well as passive means to remove the spent fuel decay heat by a combination of radiation, conduction and natural air convection. In this works are presented advances in the conceptual designs for a spent nuclear fuel system to Atucha I nuclear power plant. (author) [es

  16. Interim performance criteria for photovoltaic energy systems. [Glossary included

    Energy Technology Data Exchange (ETDEWEB)

    DeBlasio, R.; Forman, S.; Hogan, S.; Nuss, G.; Post, H.; Ross, R.; Schafft, H.

    1980-12-01

    This document is a response to the Photovoltaic Research, Development, and Demonstration Act of 1978 (P.L. 95-590) which required the generation of performance criteria for photovoltaic energy systems. Since the document is evolutionary and will be updated, the term interim is used. More than 50 experts in the photovoltaic field have contributed in the writing and review of the 179 performance criteria listed in this document. The performance criteria address characteristics of present-day photovoltaic systems that are of interest to manufacturers, government agencies, purchasers, and all others interested in various aspects of photovoltaic system performance and safety. The performance criteria apply to the system as a whole and to its possible subsystems: array, power conditioning, monitor and control, storage, cabling, and power distribution. They are further categorized according to the following performance attributes: electrical, thermal, mechanical/structural, safety, durability/reliability, installation/operation/maintenance, and building/site. Each criterion contains a statement of expected performance (nonprescriptive), a method of evaluation, and a commentary with further information or justification. Over 50 references for background information are also given. A glossary with definitions relevant to photovoltaic systems and a section on test methods are presented in the appendices. Twenty test methods are included to measure performance characteristics of the subsystem elements. These test methods and other parts of the document will be expanded or revised as future experience and needs dictate.

  17. National climate change action plans: Interim report for developing and transition countries

    Energy Technology Data Exchange (ETDEWEB)

    Benioff, R.; Ness, E.; Hirst, J. [eds.

    1997-10-01

    Under its Support for National Action Plans (SNAP) initiative, the U.S. Country Studies Program is providing financial and technical assistance to 18 countries for the development of climate change action plans. Although most of the countries have not yet completed their plans, the important lessons learned thus far are valuable and should be shared with other countries and international institutions that have an interest in the process of action plan development. This interim report describes the experience of 11 countries that are the furthest along in their planning activity and who have offered to share their results to date with the larger community of interested nations. These action plans delineate specific mitigation and adaptation measures that the countries will implement and integrate into their ongoing development programs. This report focuses on the measures the countries have selected and the methods they used to prepare their action plans. This executive summary presents key lessons and common themes using a structure similar to that used in the individual country chapters.

  18. Online Monitoring Technical Basis and Analysis Framework for Large Power Transformers; Interim Report for FY 2012

    Energy Technology Data Exchange (ETDEWEB)

    Nancy J. Lybeck; Vivek Agarwal; Binh T. Pham; Heather D. Medema; Kirk Fitzgerald

    2012-09-01

    The Light Water Reactor Sustainability program at Idaho National Laboratory (INL) is actively conducting research to develop and demonstrate online monitoring (OLM) capabilities for active components in existing Nuclear Power Plants. A pilot project is currently underway to apply OLM to Generator Step-Up Transformers (GSUs) and Emergency Diesel Generators (EDGs). INL and the Electric Power Research Institute (EPRI) are working jointly to implement the pilot project. The EPRI Fleet-Wide Prognostic and Health Management (FW-PHM) Software Suite will be used to implement monitoring in conjunction with utility partners: the Shearon Harris Nuclear Generating Station (owned by Duke Energy for GSUs, and Braidwood Generating Station (owned by Exelon Corporation) for EDGs. This report presents monitoring techniques, fault signatures, and diagnostic and prognostic models for GSUs. GSUs are main transformers that are directly connected to generators, stepping up the voltage from the generator output voltage to the highest transmission voltages for supplying electricity to the transmission grid. Technical experts from Shearon Harris are assisting INL and EPRI in identifying critical faults and defining fault signatures associated with each fault. The resulting diagnostic models will be implemented in the FW-PHM Software Suite and tested using data from Shearon-Harris. Parallel research on EDGs is being conducted, and will be reported in an interim report during the first quarter of fiscal year 2013.

  19. Assessment report on research and development activities. Activity: 'Advanced science research' (Interim report)

    International Nuclear Information System (INIS)

    2012-11-01

    Japan Atomic Energy Agency (hereinafter referred to as “JAEA”) consulted an assessment committee, “Evaluation Committee of Research Activities for Advanced Science Research” (hereinafter referred to as “Committee”) for interim assessment of “Advanced Science Research,” in accordance with “General Guideline for the Evaluation of Government Research and Development (R and D) Activities” by Cabinet Office, Government of Japan, “Guideline for Evaluation of R and D in Ministry of Education, Culture, Sports, Science and Technology” and “Regulation on Conduct for Evaluation of R and D Activities” by JAEA. In response to the JAEA's request, the Committee assessed the research programs and activities of the Advanced Science Research Center (hereinafter referred to as “ASRC”) for the period of two years from April 2010. The Committee evaluated the management and the research programs of the ASRC based on the explanatory documents prepared by the ASRC and the oral presentations with questions-and-answers by the Director and the research group leaders. This report summarizes the result of the assessment by the Committee with the Committee report attached from page 7. (author)

  20. Online Monitoring Technical Basis and Analysis Framework for Emergency Diesel Generators - Interim Report for FY 2013

    Energy Technology Data Exchange (ETDEWEB)

    Binh T. Pham; Nancy J. Lybeck; Vivek Agarwal

    2012-12-01

    The Light Water Reactor Sustainability program at Idaho National Laboratory is actively conducting research to develop and demonstrate online monitoring capabilities for active components in existing nuclear power plants. Idaho National Laboratory and the Electric Power Research Institute are working jointly to implement a pilot project to apply these capabilities to emergency diesel generators and generator step-up transformers. The Electric Power Research Institute Fleet-Wide Prognostic and Health Management Software Suite will be used to implement monitoring in conjunction with utility partners: Braidwood Generating Station (owned by Exelon Corporation) for emergency diesel generators, and Shearon Harris Nuclear Generating Station (owned by Duke Energy Progress) for generator step-up transformers. This report presents monitoring techniques, fault signatures, and diagnostic and prognostic models for emergency diesel generators. Emergency diesel generators provide backup power to the nuclear power plant, allowing operation of essential equipment such as pumps in the emergency core coolant system during catastrophic events, including loss of offsite power. Technical experts from Braidwood are assisting Idaho National Laboratory and Electric Power Research Institute in identifying critical faults and defining fault signatures associated with each fault. The resulting diagnostic models will be implemented in the Fleet-Wide Prognostic and Health Management Software Suite and tested using data from Braidwood. Parallel research on generator step-up transformers was summarized in an interim report during the fourth quarter of fiscal year 2012.

  1. Proposed plan for interim remedial measures at the 100-HR-1 Operable Unit, Hanford Site, Richland, Washington

    International Nuclear Information System (INIS)

    1995-01-01

    This proposed plan identifies the preferred alternative for interim remedial measures for remedial action of radioactive liquid waste disposal sites at the 100-HR-1 Operable Unit, located at the Hanford Site. It also summarizes other remedial alternatives evaluated for interim remedial measures in this operable unit. The intent of interim remedial measures is to speed up actions to address contaminated areas that historically received radioactive liquid waste discharges that pose a potential threat to human health and the environment. This proposed plan is being issued by the Washington State Department of Ecology (Ecology), the lead regulatory agency; the US Environmental Protection Agency (EPA), the support regulatory agency; and the US Department of Energy (DOE), the responsible agency. Ecology, EPA, and DOE are issuing this proposed plan as part of their public participation responsibilities under Section 117(a) of the Comprehensive Environmental Response, Compensation and Liability Act (CERCLA), commonly known as the ''Superfund Program.'' The proposed plan is intended to be a fact sheet for public review that (1) briefly describes the remedial alternatives analyzed; (2) proposes a preferred alternative; (3) summarizes the information relied upon to recommend the preferred alternative; and (4) provides a basis for an interim action record of decision (ROD). The preferred alternative presented in this proposed plan is removal, treatment (as appropriate), and disposal of contaminated soil and associated structures. Treatment will be conducted if there is cost benefit

  2. Interim oceanographic description of the North-East Atlantic site for the disposal of low-level radioactive waste

    International Nuclear Information System (INIS)

    Gurbutt, P.A.; Dickson, R.R.

    1983-01-01

    Within the terms of the Surveillance Mechanism for Sea Dumping of Radioactive Wastes, NEA is requested to assess the suitability of dumping sites proposed by Participating countries and to keep under review those previously thought suitable. The aim of this volume is to provide a further interim description of the North-East Atlantic dumpsite itself. Quantities of known wastes dumpings are summarized. A review of the available data on sediment distribution in the area is presented. The flow field at the site is described so that an experiment to determine the influence on the deep flow of large scale topographic features at the dumpsite. The tide gauge results are briefly presented. The state of knowledge of the hydrographic and chemical conditions prior to 1977 is reviewed; recent results are added. The results of the radioactivity determination in the surface layer (3cm thick) of box cored sediments and the vertical radioactivity profiles are presented in tables. Some results on adsorption and geochemical partitioning of long-lived radionuclides on dumpsite sediments are briefly reviewed. Biological studies have been undertaken: concentration of radionuclides in biological materials, radiation effects on the dumpsite fauna. A dose-limit (critical group) calculation model is presented. Collective dose commitment and mass transfer are briefly discussed. The concentration of radionuclides in sediments and some organisms of the Bay of Biscay has been evaluated. Some isopycnal data for the eastern Atlantic, windstress and stratification are briefly mentioned

  3. Precise orbit analysis and global verification results from ERS-1 altimetry

    Science.gov (United States)

    Shum, C. K.; Tapley, B. D.; Kozel, B. J.; Visser, P.; Ries, J. C.; Seago, J.

    1994-01-01

    A technique which employs dual satellite crossover measurements from ERS-1 and Topology Ocean Experiment (TOPEX)/Poseidon together with laser tracking data and single satellite crossover measurements for ERS-1 precision orbit determination is described. The accuracy assessment of the resulting ERS-1 orbit is provided. Results of global verification of the ERS-1 Ocean Products (OPR02) and the Interim Geophysical Data Records (IGDR) data products in terms of altimeter bias, time lag bias and sea state bias are presented.

  4. Database and Interim Glass Property Models for Hanford HLW Glasses

    International Nuclear Information System (INIS)

    Hrma, Pavel R; Piepel, Gregory F; Vienna, John D; Cooley, Scott K; Kim, Dong-Sang; Russell, Renee L

    2001-01-01

    The purpose of this report is to provide a methodology for an increase in the efficiency and a decrease in the cost of vitrifying high-level waste (HLW) by optimizing HLW glass formulation. This methodology consists in collecting and generating a database of glass properties that determine HLW glass processability and acceptability and relating these properties to glass composition. The report explains how the property-composition models are developed, fitted to data, used for glass formulation optimization, and continuously updated in response to changes in HLW composition estimates and changes in glass processing technology. Further, the report reviews the glass property-composition literature data and presents their preliminary critical evaluation and screening. Finally the report provides interim property-composition models for melt viscosity, for liquidus temperature (with spinel and zircon primary crystalline phases), and for the product consistency test normalized releases of B, Na, and Li. Models were fitted to a subset of the screened database deemed most relevant for the current HLW composition region

  5. Database and Interim Glass Property Models for Hanford HLW Glasses

    Energy Technology Data Exchange (ETDEWEB)

    Hrma, Pavel R.; Piepel, Gregory F.; Vienna, John D.; Cooley, Scott K.; Kim, Dong-Sang; Russell, Renee L.

    2001-07-24

    The purpose of this report is to provide a methodology for an increase in the efficiency and a decrease in the cost of vitrifying high-level waste (HLW) by optimizing HLW glass formulation. This methodology consists in collecting and generating a database of glass properties that determine HLW glass processability and acceptability and relating these properties to glass composition. The report explains how the property-composition models are developed, fitted to data, used for glass formulation optimization, and continuously updated in response to changes in HLW composition estimates and changes in glass processing technology. Further, the report reviews the glass property-composition literature data and presents their preliminary critical evaluation and screening. Finally the report provides interim property-composition models for melt viscosity, for liquidus temperature (with spinel and zircon primary crystalline phases), and for the product consistency test normalized releases of B, Na, and Li. Models were fitted to a subset of the screened database deemed most relevant for the current HLW composition region.

  6. Spent Fuel Long Term Interim Storage: The Spanish Policy

    International Nuclear Information System (INIS)

    Fernandez-Lopez, Javier

    2014-01-01

    ENRESA is the Spanish organization responsible for long-term management of all categories of radioactive waste and nuclear spent fuel and for decommissioning nuclear installations. It is also in charge of the management of the funds collected from waste producers and electricity consumers. The national policy about radioactive waste management is established at the General Radioactive Waste Plan by the Government upon proposal of the Ministry of Industry, Energy and Tourism. Now the Plan in force is the Sixth Plan approved in 2006. The policy on spent nuclear fuel, after description of the current available options, is set up as a long term interim storage at a Centralized Temporary Storage facility (CTS, or ATC in Spanish acronym) followed by geologic disposal, pending technological development on other options being eligible in the future. After a site selection process launched in 2009, the site for the ATC has been chosen at the end of 2011. The first steps for the implementation of the facility are described in the present paper. (authors)

  7. Permitting plan for the high-level waste interim storage

    Energy Technology Data Exchange (ETDEWEB)

    Deffenbaugh, M.L.

    1997-04-23

    This document addresses the environmental permitting requirements for the transportation and interim storage of solidified high-level waste (HLW) produced during Phase 1 of the Hanford Site privatization effort. Solidified HLW consists of canisters containing vitrified HLW (glass) and containers that hold cesium separated during low-level waste pretreatment. The glass canisters and cesium containers will be transported to the Canister Storage Building (CSB) in a U.S. Department of Energy (DOE)-provided transportation cask via diesel-powered tractor trailer. Tri-Party Agreement (TPA) Milestone M-90 establishes a new major milestone, and associated interim milestones and target dates, governing acquisition and/or modification of facilities necessary for: (1) interim storage of Tank Waste Remediation Systems (TWRS) immobilized HLW (IHLW) and other canistered high-level waste forms; and (2) interim storage and disposal of TWRS immobilized low-activity tank waste (ILAW). An environmental requirements checklist and narrative was developed to identify the permitting path forward for the HLW interim storage (HLWIS) project (See Appendix B). This permitting plan will follow the permitting logic developed in that checklist.

  8. Permitting plan for the high-level waste interim storage

    International Nuclear Information System (INIS)

    Deffenbaugh, M.L.

    1997-01-01

    This document addresses the environmental permitting requirements for the transportation and interim storage of solidified high-level waste (HLW) produced during Phase 1 of the Hanford Site privatization effort. Solidified HLW consists of canisters containing vitrified HLW (glass) and containers that hold cesium separated during low-level waste pretreatment. The glass canisters and cesium containers will be transported to the Canister Storage Building (CSB) in a U.S. Department of Energy (DOE)-provided transportation cask via diesel-powered tractor trailer. Tri-Party Agreement (TPA) Milestone M-90 establishes a new major milestone, and associated interim milestones and target dates, governing acquisition and/or modification of facilities necessary for: (1) interim storage of Tank Waste Remediation Systems (TWRS) immobilized HLW (IHLW) and other canistered high-level waste forms; and (2) interim storage and disposal of TWRS immobilized low-activity tank waste (ILAW). An environmental requirements checklist and narrative was developed to identify the permitting path forward for the HLW interim storage (HLWIS) project (See Appendix B). This permitting plan will follow the permitting logic developed in that checklist

  9. Operable Unit 3: Proposed Plan/Environmental Assessment for interim remedial action

    International Nuclear Information System (INIS)

    1993-12-01

    This document presents a Proposed Plan and an Environmental Assessment for an interim remedial action to be undertaken by the US Department of Energy (DOE) within Operable Unit 3 (OU3) at the Fernald Environmental Management Project (FEMP). This proposed plan provides site background information, describes the remedial alternatives being considered, presents a comparative evaluation of the alternatives and a rationnale for the identification of DOE's preferred alternative, evaluates the potential environmental and public health effects associated with the alternatives, and outlines the public's role in helping DOE and the EPA to make the final decision on a remedy

  10. Operable Unit 3: Proposed Plan/Environmental Assessment for interim remedial action

    Energy Technology Data Exchange (ETDEWEB)

    1993-12-01

    This document presents a Proposed Plan and an Environmental Assessment for an interim remedial action to be undertaken by the US Department of Energy (DOE) within Operable Unit 3 (OU3) at the Fernald Environmental Management Project (FEMP). This proposed plan provides site background information, describes the remedial alternatives being considered, presents a comparative evaluation of the alternatives and a rationnale for the identification of DOE`s preferred alternative, evaluates the potential environmental and public health effects associated with the alternatives, and outlines the public`s role in helping DOE and the EPA to make the final decision on a remedy.

  11. The UN Interim Administration Mission in Kosovo (UNMIK

    Directory of Open Access Journals (Sweden)

    Alfonso J. Iglesias Velasco

    2001-12-01

    Full Text Available The current situation in the Province of Kosovo in the Republic of Serbia within the Yugoslav State became unsustainable in the late 1990´s as a result of the repressive policies of the Serbian authorities toward the Kosovar Albanians. International efforts tofind a peaceful solution to the conflict were unsuccessful, in large measure on account of Serbian intransigence, and the intensification of the conflict with tragic consequences for the Kosovar civilian population led the Atlantic Alliance in the spring of 1999 to a carryout a military intervention of, to say the least, dubious legality under international law, which in turn forced Serbian leaders to bow to the application of the solution worked out by the international community in the Rambouillet Accords and set down in UN Security Council Resolution 1244 (1999 of June 10, 1999. This resolution provided for two international entities in the province, one a security force (KFOR and the other civilian, the UN Interim Administration Mission (UNMIK. This paper analyzes the mission’s mandate and structure as well as the evolution of the peace process.

  12. Kennedy Space Center Press Site (SWMU 074) Interim Measure Report

    Science.gov (United States)

    Applegate, Joseph L.

    2015-01-01

    This report summarizes the Interim Measure (IM) activities conducted at the Kennedy Space Center (KSC) Press Site ("the Press Site"). This facility has been designated as Solid Waste Management Unit 074 under KSC's Resource Conservation and Recovery Act Corrective Action program. The activities were completed as part of the Vehicle Assembly Building (VAB) Area Land Use Controls Implementation Plan (LUCIP) Elimination Project. The purpose of the VAB Area LUCIP Elimination Project was to delineate and remove soil affected with constituents of concern (COCs) that historically resulted in Land Use Controls (LUCs). The goal of the project was to eliminate the LUCs on soil. LUCs for groundwater were not addressed as part of the project and are not discussed in this report. This report is intended to meet the Florida Department of Environmental Protection (FDEP) Corrective Action Management Plan requirement as part of the KSC Hazardous and Solid Waste Amendments permit and the U.S. Environmental Protection Agency's (USEPA's) Toxic Substance Control Act (TSCA) self-implementing polychlorinated biphenyl (PCB) cleanup requirements of 40 Code of Federal Regulations (CFR) 761.61(a).

  13. Safety aspects of spent nuclear fuel interim storage installations

    International Nuclear Information System (INIS)

    Romanato, Luiz Sergio

    2007-01-01

    Nowadays safety and security of spent nuclear fuel (SNF) interim storage installations are very important, due to a great concentration of fission products, actinides and activation products. In this kind of storage it is necessary to consider the physical security. Nuclear installations have become more vulnerable. New types of accidents must be considered in the design of these installations, which in the early days were not considered like: fissile material stolen, terrorists' acts and war conflicts, and traditional accidents concerning the transport of the spent fuel from the reactor to the storage location, earthquakes occurrence, airplanes crash, etc. Studies related to airplane falling had showed that a collision of big commercials airplanes at velocity of 800 km/h against SNF storage and specially designed concrete casks, do not result in serious structural injury to the casks, and not even radionuclides liberation to the environment. However, it was demonstrated that attacks with modern military ammunitions, against metallic casks, are calamitous. The casks could not support a direct impact of this ammo and the released radioactive materials can expose the workers and public as well the local environment to harmful radiation. This paper deals about the main basic aspects of a dry SNF storage installation, that must be physically well protected, getting barriers that difficult the access of unauthorized persons or vehicles, as well as, must structurally resist to incidents or accidents caused by unauthorized intrusion. (author)

  14. 78 FR 56750 - Interim Staff Guidance on Environmental Issues Associated With New Reactors

    Science.gov (United States)

    2013-09-13

    ... COMMISSION Interim Staff Guidance on Environmental Issues Associated With New Reactors AGENCY: Nuclear... Staff Guidance (ISG) ESP/COL-ISG-026, ``Interim Staff Guidance on Environmental Issues ] Associated with... Notice: Draft Interim Staff Guidance on Environmental Issues Associated with New Reactors. ML12326A742...

  15. 78 FR 20503 - Energy Conservation Program: Availability of the Interim Technical Support Document for High...

    Science.gov (United States)

    2013-04-05

    ... CFR Part 431 RIN 1904-AC36 Energy Conservation Program: Availability of the Interim Technical Support... interim technical support document (TSD) for high-intensity discharge (HID) lamps energy conservation....aspx/ruleid/23 . This Web page contains links to the interim technical support document and other...

  16. Single-shell tank interim stabilization project plan

    International Nuclear Information System (INIS)

    Ross, W.E.

    1998-01-01

    Solid and liquid radioactive waste continues to be stored in 149 single-shell tanks at the Hanford Site. To date, 119 tanks have had most of the pumpable liquid removed by interim stabilization. Thirty tanks remain to be stabilized. One of these tanks (C-106) will be stabilized by retrieval of the tank contents. The remaining 29 tanks will be interim stabilized by saltwell pumping. In the summer of 1997, the US Department of Energy (DOE) placed a moratorium on the startup of additional saltwell pumping systems because of funding constraints and proposed modifications to the Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement) milestones to the Washington State Department of Ecology (Ecology). In a letter dated February 10, 1998, Final Determination Pursuant to Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement) in the Matter of the Disapproval of the DOE's Change Control Form M-41-97-01 (Fitzsimmons 1998), Ecology disapproved the DOE Change Control Form M-41-97-01. In response, Fluor Daniel Hanford, Inc. (FDH) directed Lockheed Martin Hanford Corporation (LNMC) to initiate development of a project plan in a letter dated February 25, 1998, Direction for Development of an Aggressive Single-Shell Tank (SST) Interim Stabilization Completion Project Plan in Support of Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement). In a letter dated March 2, 1998, Request for an Aggressive Single-Shell Tank (SST) Interim Stabilization Completion Project Plan, the DOE reaffirmed the need for an aggressive SST interim stabilization completion project plan to support a finalized Tri-Party Agreement Milestone M-41 recovery plan. This project plan establishes the management framework for conduct of the TWRS Single-Shell Tank Interim Stabilization completion program. Specifically, this plan defines the mission needs and requirements; technical objectives and approach; organizational structure, roles, responsibilities

  17. Unit cell modeling in support of interim performance assessment for low level tank waste disposal

    Energy Technology Data Exchange (ETDEWEB)

    Kline, N.W., Westinghouse Hanford

    1996-08-01

    A unit cell model is used to simulate the base analysis case and related sensitivity cases for the interim performance assessment of low level tank waste disposal. Simulation case results are summarized in terms of fractional contaminant release rates to the vadose zone and to the water table at the unconfined aquifer. Results suggest that the crushed glass water conditioning layer at the top of the facility and the chemical retardation pad at the bottom of the facility can be important components of the facility. Results also suggest that the release rates to the water table are dominated by the release rate from the waste form.

  18. Fuel model studies. Comparison of our present version of GAPCON-THERMAL-2 with results from the EPRI code comparison study. Partial report

    International Nuclear Information System (INIS)

    Malen, K.; Jansson, L.

    1978-08-01

    Runs with our present version of GAPCON-THERMAL-2 have been compared to results from the EPRI code comparison study. Usually also our version of GAPCON predicts high temperatures, 100-300 K or 10-15% higher than average code predictions and experimental results. The well-known temperaturegas release instablility is found also with GAPCON. In this case one identifies the gas release limits 1400 deg C and 1700 deg C as instablility points. (author)

  19. Prof. Samuel ting presents results from AMS experiment at CERN main auditorium. Geneva 3 April 2013. The international team running the Alpha Magnetic Spectrometer (AMS1) today announced the first results in its search for dark matter

    CERN Multimedia

    Samuel Morier-Genoud

    2013-01-01

    Geneva 3 April 2013. The international team running the Alpha Magnetic Spectrometer (AMS) today announced the first results in its search for dark matter. The results, presented by AMS spokesperson Professor Samuel Ting in a seminar at CERN, are to be published in the journal Physical Review Letters. They report the observation of an excess of positrons in the cosmic ray flux

  20. Interim safety basis for fuel supply shutdown facility

    International Nuclear Information System (INIS)

    Brehm, J.R.; Deobald, T.L.; Benecke, M.W.; Remaize, J.A.

    1995-01-01

    This ISB in conjunction with the new TSRs, will provide the required basis for interim operation or restrictions on interim operations and administrative controls for the Facility until a SAR is prepared in accordance with the new requirements. It is concluded that the risk associated with the current operational mode of the Facility, uranium closure, clean up, and transition activities required for permanent closure, are within Risk Acceptance Guidelines. The Facility is classified as a Moderate Hazard Facility because of the potential for an unmitigated fire associated with the uranium storage buildings

  1. Single-shell tank interim stabilization risk analysis

    International Nuclear Information System (INIS)

    Basche, A.D.

    1998-01-01

    The purpose of the Single-Shell Tank (SST) Interim Stabilization Risk Analysis is to provide a cost and schedule risk analysis of HNF-2358, Rev. 1, Single-Shell Tank Interim Stabilization Project Plan (Project Plan) (Ross et al. 1998). The analysis compares the required cost profile by fiscal year (Section 4.2) and revised schedule completion date (Section 4.5) to the Project Plan. The analysis also evaluates the executability of the Project Plan and recommends a path forward for risk mitigation

  2. Quality of claims, references and the presentation of risk results in medical journal advertising: a comparative study in Australia, Malaysia and the United States.

    Science.gov (United States)

    Othman, Noordin; Vitry, Agnes I; Roughead, Elizabeth E

    2010-05-29

    Journal advertising is used by pharmaceutical companies to disseminate medicine information to doctors. The quality of claims, references and the presentation of risk results in Australia and the US has been questioned in several studies. No recent evidence is available on the quality of claims, references and the presentation of risk results in journal advertising in Australia and the US and no Malaysian data have been published. The aim of this study was to compare the quality of claims, references and the presentation of risk results in journal advertising in these three countries. A consecutive sample of 85 unique advertisements from each country was selected from journal advertising published between January 2004 to December 2006. Claims, references and the presentation of risk results in medical journal advertising were compared between the three countries. Less than one-third of the claims were unambiguous claims (Australia, 30%, Malaysia 17%, US, 23%). In Malaysia significantly less unambiguous claims were provided than in Australia and the US (P references than other claims (80%). Most evidence was obtained from at least one randomized controlled trial, a systematic review or meta-analysis (Australia, 84%, Malaysia, 81%, US, 76%) with journal articles being the most commonly cited references in all countries. Data on file were significantly more likely to be cited in the US (17%) than in Australia (2%) and Malaysia (4%) (P references in the US. The use of relative rather than absolute benefits may overemphasize the benefit of medicines which may leave doctors susceptible to misinterpreting information.

  3. Data Analysis of GPM Constellation Satellites-IMERG and ERA-Interim precipitation products over West of Iran

    Science.gov (United States)

    Sharifi, Ehsan; Steinacker, Reinhold; Saghafian, Bahram

    2016-04-01

    of false detection (POFD) IMERG yields a better value of POD, TS, FAR and POFD in comparison to era-Interim. Overall, ERA-Interim product produced fewer robust results when compared to IMERG.

  4. Interim storage packagings for spent fuels : how to optimize an universal design to local needs

    International Nuclear Information System (INIS)

    Konirsch, O.; Kawabata, T.; Hunter, I.

    2003-01-01

    For the last ten years, the interim storage market for spent fuels issued from Nuclear Power Plants has significantly increased all over the world: there are presently many storage projects either in Asia, in North America and in Europe. Even if there is no international regulation on that field, there is a big concern from all the nuclear industry to try to harmonise the specification for the definition of the Interim Storage Systems. One example of this harmonisation is the common and general wish to develop systems, which allow to be easily transportable either to a final repository or to a reprocessing plant. As this destination is generally not yet known, the storage system should be able to be transported all over the world. On the other hand, the specific requirement for the storage facility and its associated equipment are subject to local and/or national regulation. COGEMA LOGISTICS Group has developed two different technologies which are compatible with this principle of harmonisation: dual purpose metallic cask represented by the TN24 family and the concrete storage system NUHOMS(R). For both technologies, basic designs can be adapted to the local needs in term of performance and of national regulation. To cover all the world, COGEMA LOGISTICS Group has its own subsidiaries, in Asia, in North America and in Europe with their own autonomous engineers teams for designing, licensing, manufacturing and delivering the transport/storage products. COGEMA LOGISTICS Group is presently the leader on the dry interim storage market. The purpose of the present paper is to show how it is possible to optimise a basic existing design of a dual purpose metallic cask for a local need of storage. Taking into account the national rules for storage and the international regulation for transport, the designer shall minimise the development cost for a completely new design and maximise the capacity of the packaging regarding the allowable limits in the Nuclear Power Plant, in

  5. Surface Water Interim Measures/Interim Remedial Action Plan/ Environmental and Decision Document, South Walnut Creek Basin, Operable Unit No.2

    International Nuclear Information System (INIS)

    1991-01-01

    Water quality investigations have identified the presence of volatile organic compound (VOC) and radionuclide contamination of surface water at the Rocky Flats Plant (RFP). The subject interim Measures/Interim Remedial Action Plan/Environmental Assessment (IM/IRAP/EA) addresses contaminated surface water in a portion of the South Walnut Creek drainage basin located within an area identified as Operable Unit No. 2 (OU 2). There is no immediate threat to public health and the environment posed by this surface water contamination. The affected surface water is contained within the plant boundary by existing detention ponds, and is treated prior to discharge for removal of volatile contaminants and suspended particulates to which radionuclides, if present, are likely to absorb. However, there is a potential threat and the Department of Energy (DOE) is implementing this Surface Water IM/IRAP at the request of the US Environmental Protection Agency (EPA) and Colorado Department of Health (CDH). Implementation of the Surface Water IM/IRA will enhance the DOE's efforts towards containing and managing contaminated surface water, and will mitigate downgradient migration of contaminants. Another factor in implementing this IM/IRA is the length of time it will take to complete the investigations and engineering studies necessary to determine the final remedy for OU 2. 44 refs., 23 figs., 14 tabs

  6. KSC Press Site Transformer Bldg. (K7-1205c) SWMU 074 Interim Measure Work Plan

    Science.gov (United States)

    Starr, A. Scott; Applegate, Joe

    2014-01-01

    This document presents and discusses the Interim Measure (IM) Work Plan for the Press Site Transformer Building (K7-1205C). The purpose of the proposed IM activities is to remove soil affected with polychlorinated biphenyls (PCBs) greater than the Florida Department of Environmental Protection (FDEP) residential direct-exposure Soil Cleanup Target Level (R-SCTL) of 0.5 milligrams per kilogram and encapsulate concrete exhibiting PCB concentration greater than the Toxic Substance Control Act (TSCA) threshold of 50 milligrams per kilogram.

  7. An interim reference model for the middle atmosphere water vapor distribution

    Science.gov (United States)

    Russell, J. M., III

    1987-01-01

    Nimbus 7 LIMS data are used to determine monthly and seasonal zonal mean reference stratospheric profiles over selected latitude bands, and other ground and airborne microwave data are combined with the LIMS data to construct an interim reference profile from the tropopause to 80 km for the midlatitude region averaged over the winter and spring periods. The present profiles indicate the presence of a hygropause near 50 mb pressure in the tropics, a relatively constant mixing ratio distribution with a height of 4.7-5 ppmv in the midlatitude and high latitude stratosphere, and a decrease in the midlatitude mesosphere to 1 ppmv at about 80 km.

  8. Proposed plan for interim remedial measure at the 100-KR-4 operable unit, Revision 1

    International Nuclear Information System (INIS)

    1995-09-01

    This proposed plan identifies the preferred alternative for an interim remedial action plan for the 100-KR-4 Operable Unit at the Hanford Site. The alternative presented is to remove contaminated groundwater from the Unit, treat it by ion exchange, and then dispose of treated groundwater by using upgradient injection wells to return it to the acquifer. This will protect the Columbia River environment from toxic hexavalent chromium. This alternative is the initial recommendation of the EPA, Ecology, and the DOE. Public comment on this plan is invited

  9. Interim performance specifications for conceptual waste-package designs for geologic isolation in salt repositories

    International Nuclear Information System (INIS)

    1983-06-01

    The interim performance specifications and data requirements presented apply to conceptual waste package designs for all waste forms which will be isolated in salt geologic repositories. The waste package performance specifications and data requirements respond to the waste package performance criteria. Subject areas treated include: containment and controlled release, operational period safety, criticality control, identification, and waste package performance testing requirements. This document was generated for use in the development of conceptual waste package designs in salt. It will be revised as additional data, analyses, and regulatory requirements become available

  10. Fast flux test facility interim examination and maintenance cell fuel duct cutters: Remote operations design considerations

    International Nuclear Information System (INIS)

    Gibbons, P.W.

    1988-11-01

    Two remotely operated milltype slitting cutters, specifically designed for remote, hot-cell use have been in service in the Fast Flux Test Facility (FFTF) Interim Examination and Maintenance (IEM) Cell for 3 and 4 yr, respectively without the benefit of hands-on maintenance. These cutters are used to sever the outer duct of Driver Fuel Assemblies (DFA) being dismantled for further examination elsewhere. During this period, twelve DFAs requiring duct cutting were dismantled in the IEM Cell. A discussion of the remote design features of those cutters is presented that highlights features that were successful and addresses areas that needed improvement. 3 refs., 7 figs

  11. Single-shell tank interim stabilization project plan

    Energy Technology Data Exchange (ETDEWEB)

    Ross, W.E.

    1998-05-11

    This project plan establishes the management framework for conduct of the TWRS Single-Shell Tank Interim Stabilization completion program. Specifically, this plan defines the mission needs and requirements; technical objectives and approach; organizational structure, roles, responsibilities, and interfaces; and operational methods. This plan serves as the project executional baseline.

  12. The Forward Testing Effect: Interim Testing Enhances Inductive Learning

    Science.gov (United States)

    Yang, Chunliang; Shanks, David R.

    2018-01-01

    "Induction" refers to the process in which people generalize their previous experience when making uncertain inferences about the environment that go beyond direct experience. Here we show that interim tests strongly enhance inductive learning. Participants studied the painting styles of eight famous artists across four lists, each…

  13. 46 CFR 308.303 - Amounts insured under interim binder.

    Science.gov (United States)

    2010-10-01

    ... 308.303 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE Second Seamen's War Risk Insurance § 308.303 Amounts insured under interim binder. The amounts insured are the amounts specified in the Second Seamen's War Risk Policy (1955) or as modified by shipping...

  14. Options for the interim storage of spent fuel

    International Nuclear Information System (INIS)

    Kromar, M.; Kurincic, B.

    1995-01-01

    Different concepts for the interim storage of spent fuel arising from operation of a NPP are discussed. We considered at reactor as well as away from reactor storage options. Included are enhancements of existing storage capabilities and construction of a new wet or dry storage facility. (author)

  15. 40 CFR 266.103 - Interim status standards for burners.

    Science.gov (United States)

    2010-07-01

    ... during interim status to industrial furnaces (e.g., kilns, cupolas) that feed hazardous waste for a..., owners and operators shall not feed hazardous waste that has a heating value less than 5,000 Btu/lb, as..., beryllium, cadmium, chromium, lead, mercury, silver, and thallium in each feed stream (hazardous waste...

  16. System Specification for Immobilized High-Level Waste Interim Storage

    International Nuclear Information System (INIS)

    CALMUS, R.B.

    2000-01-01

    This specification establishes the system-level functional, performance, design, interface, and test requirements for Phase 1 of the IHLW Interim Storage System, located at the Hanford Site in Washington State. The IHLW canisters will be produced at the Hanford Site by a Selected DOE contractor. Subsequent to storage the canisters will be shipped to a federal geologic repository

  17. 39 CFR 211.4 - Interim personnel regulations.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Interim personnel regulations. 211.4 Section 211.4... under the Postal Reorganization Act. (b) Continuation of Personnel Provisions of Former title 39, U.S.C... collective bargaining agreement under the Postal Reorganization Act, all provisions of former title 39, U.S.C...

  18. Single Shell Tank (SST) Interim Stabilization Project Plan

    Energy Technology Data Exchange (ETDEWEB)

    VLADIMIROFF, D.T.; BOYLES, V.C.

    2000-05-22

    This project plan establishes the management framework for the conduct of the CHG Single-Shell Tank Interim Stabilization completion program. Specifically, this plan defines the mission needs and requirements; technical objectives and approach; organization structure, roles, responsibilities, and interfaces; and operational methods. This plan serves as the project executional baseline.

  19. Students' interim literacies as a dynamic resource for teaching and ...

    African Journals Online (AJOL)

    This article explores the notion of 'interim literacies'by drawing on data from a research project which used linguistic and intertextual analysis of first year student writing in economics to investigate the intersection of academic discourse and student voice. This research has provided a rich set of data to illustrate the ways in ...

  20. 17 CFR 210.10-01 - Interim financial statements.

    Science.gov (United States)

    2010-04-01

    ... flows from operating activities and showing cash changes from investing and financing activities... dividends declared per share applicable to common stock. The basis of the earnings per share computation... registrant, and where consistent with the protection of investors, permit the omission of any of the interim...

  1. The use of interim data and Data Monitoring Committee recommendations in randomized controlled trial reports: frequency, implications and potential sources of bias

    Directory of Open Access Journals (Sweden)

    Hampton John

    2008-03-01

    Full Text Available Abstract Background Interim analysis of accumulating trial data is important to protect participant safety during randomized controlled trials (RCTs. Data Monitoring Committees (DMCs often undertake such analyses, but their widening role may lead to extended use of interim analysis or recommendations that could potentially bias trial results. Methods Systematic search of eight major publications: Annals of Internal Medicine, BMJ, Circulation, CID, JAMA, JCO, Lancet and NEJM, including all randomised controlled trials (RCTs between June 2000 and May 2005 to identify RCTs that reported use of interim analysis, with or without DMC involvement. Recommendations made by the DMC or based on interim analysis were identified and potential sources of bias assessed. Independent double data extraction was performed on all included trials. Results We identified 1772 RCTs, of which 470 (27%; 470/1772 reported the use of a DMC and a further 116 (7%; 116/1772 trials reported some form of interim analysis without explicit mention of a DMC. There were 28 trials (24 with a formal DMC, randomizing a total of 79396 participants, identified as recommending changes to the trial that may have lead to biased results. In most of these, some form of sample size re-estimation was recommended with four trials also reporting changes to trial endpoints. The review relied on information reported in the primary publications and methods papers relating to the trials, higher rates of use may have occurred but not been reported. Conclusion The reported use of interim analysis and DMCs in clinical trials has been increasing in recent years. It is reassuring that in most cases recommendations were made in the interest of participant safety. However, in practice, recommendations that may lead to potentially biased trial results are being made.

  2. International Peer Review of Swedish Nuclear Fuel and Waste Management Company's SR-Can interim report

    International Nuclear Information System (INIS)

    Sagar, Budhi; Bailey, Lucy; Bennett, David G.; Egan, Mike; Roehlig, Klaus

    2004-12-01

    SKB has produced an interim safety assessment report as part of its work to develop a licence application for the construction of a spent nuclear fuel encapsulation plant. The purpose of the interim report is to set out and demonstrate SKB's proposed methodology for long-term safety assessment. The aim of producing an interim report is to allow the Swedish regulatory authorities (SKI and SSI) to review and comment on SKB's proposed methodology before it is used in support of a formal licence application. To help inform their review of SKB's proposed methodology, the authorities appointed an international review team (IRT) to carry out a review of SKB's interim safety assessment report. Comments from the IRT are presented in this document and will be considered by the regulatory authorities in developing their own view of SKB's proposed methodology. The IRT's review included examination of SKB's documentation (the 'Interim Main Report of the Safety Assessment SR-Can' and four supporting documents) and hearings with SKB staff and contractors. The hearings provided an opportunity for the IRT to discuss the SR-Can safety assessment with the authors and contributors to SKB's work. As directed by SKI and SSI, the IRT's review focused on methodological aspects and sought to determine whether SKB's proposed safety assessment methodology: (i) is fit for the purpose of supporting a licence application; (ii) has a reasonable prospect of leading to a safety assessment that is sufficiently comprehensive, reproducible, traceable and transparent; (iii) is compatible with the authorities' regulations and guidance. No evaluation of long term safety or site acceptability was attempted by the IRT. At the request of SKI and SSI, the IRT's review considered and made recommendations on the following issues: Description of the initial state of the repository and its components; Description of features, events and processes (FEPs) relevant to repository evolution; Strategy for safety

  3. Randomized Crossover Study of Training Benefits of High Fidelity ECMO Simulation versus Porcine Animal Model An Interim Report

    Science.gov (United States)

    2017-02-25

    High- Fidelity ECMO Simulation versus Porcine Animal Model - An Interim Report presented at/published to ECMO and the Advanced Therapies for...event. If the sponsor of a conference or meeting is a non-DoD commercial entity or an entity seeking to do business with the government, then your...approval.) Randomized Crossover Study of Training Benefits of High-Fidelity ECMO Simulation versus Porcine Animal Model 6. TITLE OF MATERIAL TO BE

  4. A technique for fabricating single screw-retained implant-supported interim crowns in conjunction with implant surgery.

    Science.gov (United States)

    McRory, M Eric; Cagna, David R

    2014-06-01

    This article presents an intraoral technique for fabricating single screw-retained implant-supported interim crowns immediately after surgical implant placement in extraction sites. The technique may be used with any implant system that provides a provisional abutment or an open-tray impression coping that can be modified for use as a provisional abutment. Copyright © 2014 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

  5. Reliability Centered Maintenance for Savannah River Site's interim waste management facilities

    International Nuclear Information System (INIS)

    Hauer, K.A.; Wilson, J.F.

    1992-01-01

    The application of Reliability Centered Maintenance (RCM) has been shown to be an effective means to optimize maintenance programs or to establish new programs. The key to success of any RCM program is to customize the methodology to meet the specific needs of the implementing organization. This paper discusses how RCM is being used to establish the preventive maintenance program and how the resulting system data is being used to support the Technical Baseline reconstitution effort for the interim Waste Management Division of Westinghouse Savannah River Company (WSRC)

  6. Reliability Centered Maintenance for Savannah River Site`s interim waste management facilities. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Hauer, K.A. [Westinghouse Savannah River Co., Aiken, SC (United States); Wilson, J.F. [PRC, Inc. (US)

    1992-06-01

    The application of Reliability Centered Maintenance (RCM) has been shown to be an effective means to optimize maintenance programs or to establish new programs. The key to success of any RCM program is to customize the methodology to meet the specific needs of the implementing organization. This paper discusses how RCM is being used to establish the preventive maintenance program and how the resulting system data is being used to support the Technical Baseline reconstitution effort for the interim Waste Management Division of Westinghouse Savannah River Company (WSRC).

  7. Reliability Centered Maintenance for Savannah River Site's interim waste management facilities

    Energy Technology Data Exchange (ETDEWEB)

    Hauer, K.A. (Westinghouse Savannah River Co., Aiken, SC (United States)); Wilson, J.F. (PRC, Inc. (US))

    1992-01-01

    The application of Reliability Centered Maintenance (RCM) has been shown to be an effective means to optimize maintenance programs or to establish new programs. The key to success of any RCM program is to customize the methodology to meet the specific needs of the implementing organization. This paper discusses how RCM is being used to establish the preventive maintenance program and how the resulting system data is being used to support the Technical Baseline reconstitution effort for the interim Waste Management Division of Westinghouse Savannah River Company (WSRC).

  8. Optimal Futility Interim Design: A Predictive Probability of Success Approach with Time-to-Event Endpoint.

    Science.gov (United States)

    Tang, Zhongwen

    2015-01-01

    An analytical way to compute predictive probability of success (PPOS) together with credible interval at interim analysis (IA) is developed for big clinical trials with time-to-event endpoints. The method takes account of the fixed data up to IA, the amount of uncertainty in future data, and uncertainty about parameters. Predictive power is a special type of PPOS. The result is confirmed by simulation. An optimal design is proposed by finding optimal combination of analysis time and futility cutoff based on some PPOS criteria.

  9. Interim guidance risk assessment of the device assembly facility at the Nevada test site

    International Nuclear Information System (INIS)

    Altenbach, T.J.

    1996-05-01

    The risks of plutonium dispersal and/or high explosive detonation from nuclear explosive operations at the Device Assembly Facility were examined in accordance with DOE Order 5610.11 and the Interim Guidance. The assessment consisted of a qualitative task and hazards analysis, and a quantitative risk screening. Results are displayed on risk matrices for the major types of operations. Most accident scenarios were considered to have Low risk; a few scenarios have Moderate risk; and none have High risk. The highest risk scenarios (Moderate category) consist of a high explosive detonation during assembly operations in a cell, with bare conventional high explosive surrounding the pit

  10. Thermal analysis of the unloading cell of the Spanish centralized interim storage facility (CISF)

    International Nuclear Information System (INIS)

    Perez Dominguez, J. R.; Perez Vara, R.; Huelamo Martinez, E.

    2016-01-01

    This article deals with the thermal analysis performed for the Untoading Cell of Spain Centralized Interim Storage Facility, CISF (ATC, in Spanish). The analyses are done using computational fluid dynamics (CFD) simulation, with the aim of obtaining the air flow required to remove the residual heat of the elements stored in the cell. Compliance with the admissible heat limits is checked with the results obtained in the various operation and accident modes. The calculation model is flexible enough to allow carrying out a number of sensitivity analyses with the different parameters involved in the process. (Author)

  11. Evaluation of Cloud Physical Properties of ECMWF Analysis and Re-Analysis (ERA-40 and ERA Interim) against CERES Tropical Deep Convective Cloud Object Observations

    Science.gov (United States)

    Xu, Kuan-Man

    2008-01-01

    This study presents an approach that converts the vertical profiles of grid-averaged cloud properties from large-scale models to probability density functions (pdfs) of subgrid-cell cloud physical properties measured at satellite footprints. Cloud physical and radiative properties, rather than just cloud and precipitation occurrences, of assimilated cloud systems by the European Center for Medium-range Weather Forecasts (ECMWF) operational analysis (EOA) and ECMWF Re-Analyses (ERA-40 and ERA Interim) are validated against those obtained from Earth Observing System satellite cloud object data for January-August 1998 and March 2000 periods. These properties include ice water path (IWP), cloud-top height and temperature, cloud optical depth and solar and infrared radiative fluxes. Each cloud object, a contiguous region with similar cloud physical properties, is temporally and spatially matched with EOA and ERA-40 data. Results indicate that most pdfs of EOA and ERA-40 cloud physical and radiative properties agree with those of satellite observations of the tropical deep convective cloud-object type for the January-August 1998 period. There are, however, significant discrepancies in selected ranges of the cloud property pdfs such as the upper range of EOA cloud top height. A major discrepancy is that the dependence of the pdfs on the cloud object size for both EOA and ERA-40 is not as strong as in the observations. Modifications to the cloud parameterization in ECMWF that occurred in October 1999 eliminate the clouds near the tropopause but shift power of the pdf to lower cloud-top heights and greatly reduce the ranges of IWP and cloud optical depth pdfs. These features persist in ERA-40 due to the use of the same cloud parameterizations. The downgrade of data assimilation technique and the lack of snow water content information in ERA-40, not the coarser horizontal grid resolution, are also responsible for the disagreements with observed pdfs of cloud physical

  12. Adapted Treatment Guided by Interim PET-CT Scan in Advanced Hodgkin’s Lymphoma

    Science.gov (United States)

    Johnson, Peter; Federico, Massimo; Kirkwood, Amy; Fosså, Alexander; Berkahn, Leanne; Carella, Angelo; d’Amore, Francesco; Enblad, Gunilla; Franceschetto, Antonella; Fulham, Michael; Luminari, Stefano; O’Doherty, Michael; Patrick, Pip; Roberts, Thomas; Sidra, Gamal; Stevens, Lindsey; Smith, Paul; Trotman, Judith; Viney, Zaid; Radford, John; Barrington, Sally

    2016-01-01

    Background We tested interim positron-emission tomography–computed tomography (PET-CT) as a measure of early response to chemotherapy in order to guide treatment for patients with advanced Hodgkin’s lymphoma. Methods Patients with newly diagnosed advanced classic Hodgkin’s lymphoma underwent a baseline PET-CT scan, received two cycles of ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine) chemotherapy, and then underwent an interim PET-CT scan. Images were centrally reviewed with the use of a 5-point scale for PET findings. Patients with negative PET findings after two cycles were randomly assigned to continue ABVD (ABVD group) or omit bleomycin (AVD group) in cycles 3 through 6. Those with positive PET findings after two cycles received BEACOPP (bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisone). Radiotherapy was not recommended for patients with negative findings on interim scans. The primary outcome was the difference in the 3-year progression-free survival rate between randomized groups, a noninferiority comparison to exclude a difference of 5 or more percentage points. Results A total of 1214 patients were registered; 937 of the 1119 patients (83.7%) who underwent an interim PET-CT scan according to protocol had negative findings. With a median follow-up of 41 months, the 3-year progression-free survival rate and overall survival rate in the ABVD group were 85.7% (95% confidence interval [CI], 82.1 to 88.6) and 97.2% (95% CI, 95.1 to 98.4), respectively; the corresponding rates in the AVD group were 84.4% (95% CI, 80.7 to 87.5) and 97.6% (95% CI, 95.6 to 98.7). The absolute difference in the 3-year progression-free survival rate (ABVD minus AVD) was 1.6 percentage points (95% CI, −3.2 to 5.3). Respiratory adverse events were more severe in the ABVD group than in the AVD group. BEACOPP was given to the 172 patients with positive findings on the interim scan, and 74.4% had negative findings on a third

  13. The Nainital-Cape Survey. II. Report for pulsation in five chemically peculiar A-type stars and presentation of 140 null results

    Science.gov (United States)

    Joshi, S.; Mary, D. L.; Martinez, P.; Kurtz, D. W.; Girish, V.; Seetha, S.; Sagar, R.; Ashoka, B. N.

    2006-08-01

    Aims.We search for photometric variability in chemically peculiar A type stars in the northern hemisphere. Methods: .High-speed photometric observations of Ap and Am star candidates have been carried out from ARIES (Manora Peak, Nainital) using a three-channel fast photometer attached to the ARIES 104-cm Sampurnanand telescope. Results: .This paper presents three new variables: HD 113878, HD 118660 and HD 207561. During the time span of the survey (1999 December to 2004 January) pulsations of the δ Sct type were also found for the two evolved Am stars HD 102480 and HD 98851, as reported in Joshi et al. (2002, 2003). Additionally, we present 140 null results of the survey for this time span. Conclusions: .The star HD 113878 pulsates with a period of 2.31 h, which is typical of δ Sct stars. HD 118660 exhibits multi-periodic variability with a prominent period of nearly 1 h. These periods need to be investigated and make HD 118660 a particularly interesting target for further observations. For HD 207561, a star classified as Am, a probable pulsation with a period of 6 min was found in the light curves obtained on two consecutive nights. Both HD 102480 and HD 98851 exhibit unusual alternating high and low amplitude maxima, with a period ratio of 2:1. The analysis of the null results confirms the photometric quality of the Nainital site.

  14. SLIGHTLY IRRADIATED FUEL (SIF) INTERIM DISPOSITION PROJECT

    International Nuclear Information System (INIS)

    Norton, S.H.

    2010-01-01

    CH2M HILL Plateau Remediation Company (CH2M HILL PRC) is proud to submit the Slightly Irradiated Fuel (SIF) Interim Disposition Project for consideration by the Project Management Institute as Project of the Year for 2010. The SIF Project was a set of six interrelated sub-projects that delivered unique stand-alone outcomes, which, when integrated, provided a comprehensive and compliant system for storing high risk special nuclear materials. The scope of the six sub-projects included the design, construction, testing, and turnover of the facilities and equipment, which would provide safe, secure, and compliant Special Nuclear Material (SNM) storage capabilities for the SIF material. The project encompassed a broad range of activities, including the following: Five buildings/structures removed, relocated, or built; Two buildings renovated; Structural barriers, fencing, and heavy gates installed; New roadways and parking lots built; Multiple detection and assessment systems installed; New and expanded communication systems developed; Multimedia recording devices added; and A new control room to monitor all materials and systems built. Project challenges were numerous and included the following: An aggressive 17-month schedule to support the high-profile Plutonium Finishing Plant (PFP) decommissioning; Company/contractor changeovers that affected each and every project team member; Project requirements that continually evolved during design and construction due to the performance- and outcome-based nature ofthe security objectives; and Restrictions imposed on all communications due to the sensitive nature of the projects In spite of the significant challenges, the project was delivered on schedule and $2 million under budget, which became a special source of pride that bonded the team. For years, the SIF had been stored at the central Hanford PFP. Because of the weapons-grade piutonium produced and stored there, the PFP had some of the tightest security on the Hanford

  15. SLIGHTLY IRRADIATED FUEL (SIF) INTERIM DISPOSITION PROJECT

    Energy Technology Data Exchange (ETDEWEB)

    NORTON SH

    2010-02-23

    CH2M HILL Plateau Remediation Company (CH2M HILL PRC) is proud to submit the Slightly Irradiated Fuel (SIF) Interim Disposition Project for consideration by the Project Management Institute as Project of the Year for 2010. The SIF Project was a set of six interrelated sub-projects that delivered unique stand-alone outcomes, which, when integrated, provided a comprehensive and compliant system for storing high risk special nuclear materials. The scope of the six sub-projects included the design, construction, testing, and turnover of the facilities and equipment, which would provide safe, secure, and compliant Special Nuclear Material (SNM) storage capabilities for the SIF material. The project encompassed a broad range of activities, including the following: Five buildings/structures removed, relocated, or built; Two buildings renovated; Structural barriers, fencing, and heavy gates installed; New roadways and parking lots built; Multiple detection and assessment systems installed; New and expanded communication systems developed; Multimedia recording devices added; and A new control room to monitor all materials and systems built. Project challenges were numerous and included the following: An aggressive 17-month schedule to support the high-profile Plutonium Finishing Plant (PFP) decommissioning; Company/contractor changeovers that affected each and every project team member; Project requirements that continually evolved during design and construction due to the performance- and outcome-based nature ofthe security objectives; and Restrictions imposed on all communications due to the sensitive nature of the projects In spite of the significant challenges, the project was delivered on schedule and $2 million under budget, which became a special source of pride that bonded the team. For years, the SIF had been stored at the central Hanford PFP. Because of the weapons-grade piutonium produced and stored there, the PFP had some of the tightest security on the Hanford

  16. Safety report for Central Interim Storage facility for radioactive waste from small producers

    International Nuclear Information System (INIS)

    Zeleznik, N.; Mele, I.

    2004-01-01

    protection and remediation of minor defects in the facility. The safety report also incorporates the implementation projects for the inventory rearrangement and the projected waste quantities up to 2013, when the LILW repository should be available. The most important part of the safety report deals with safety analyses of all relevant operational conditions which could influence safety of the storage and its inventory, taking into account also the phase of reconstruction works. The Safety Report is prepared in accordance with the requirements of Regulation E2 (Pravilnik E2) and The Act on Ionising Radiation Protection and Nuclear Safety from 2002. After defining the objective of the safety report, the chapters deal with the following topics: The safety approach to the LILW storage, Description and location analysis of the Central interim storage, Technical characteristic of the Central interim storage, Safety analysis of the Central interim storage, Organizational measures for construction and pre-operational testing, Organizational measures for commissioning and normal operation of the Central interim storage, Operational conditions and limitations, Ionizing radiation protection service, its methods and equipment, Radioactive waste management and disposal, Review of the plans, measures and procedures to prevent radiological accidents, Quality assurance programme, Review of the measures for physical protection of the LILW storage and stored radioactive waste, Planned measures and necessary equipment for closure of the Central interim storage. The details on preparation of the Safety report, including the dilemmas and comments on different chapters, are presented in this paper. The most important findings of the safety analysis are also given.(author)

  17. Adapted Treatment Guided by Interim PET-CT Scan in Advanced Hodgkin's Lymphoma.

    Science.gov (United States)

    Johnson, Peter; Federico, Massimo; Kirkwood, Amy; Fosså, Alexander; Berkahn, Leanne; Carella, Angelo; d'Amore, Francesco; Enblad, Gunilla; Franceschetto, Antonella; Fulham, Michael; Luminari, Stefano; O'Doherty, Michael; Patrick, Pip; Roberts, Thomas; Sidra, Gamal; Stevens, Lindsey; Smith, Paul; Trotman, Judith; Viney, Zaid; Radford, John; Barrington, Sally

    2016-06-23

    -free survival rate was 67.5% and the overall survival rate 87.8%. A total of 62 patients died during the trial (24 from Hodgkin's lymphoma), for a 3-year progression-free survival rate of 82.6% and an overall survival rate of 95.8%. Although the results fall just short of the specified noninferiority margin, the omission of bleomycin from the ABVD regimen after negative findings on interim PET resulted in a lower incidence of pulmonary toxic effects than with continued ABVD but not significantly lower efficacy. (Funded by Cancer Research UK and Others; ClinicalTrials.gov number, NCT00678327.).

  18. Interim-treatment quantitative PET parameters predict progression and death among patients with hodgkin's disease

    International Nuclear Information System (INIS)

    Tseng, Diane; Tran, Phuoc T; Rachakonda, Leelanand P; Su, Zheng; Advani, Ranjana; Horning, Sandra; Hoppe, Richard T; Quon, Andrew; Graves, Edward E; Loo, Billy W Jr

    2012-01-01

    We hypothesized that quantitative PET parameters may have predictive value beyond that of traditional clinical factors such as the International Prognostic Score (IPS) among Hodgkin's disease (HD) patients. Thirty HD patients treated at presentation or relapse had staging and interim-treatment PET-CT scans. The majority of patients (53%) had stage III-IV disease and 67% had IPS ≥ 2. Interim-treatment scans were performed at a median of 55 days from the staging PET-CT. Chemotherapy regimens used: Stanford V (67%), ABVD (17%), VAMP (10%), or BEACOPP (7%). Hypermetabolic tumor regions were segmented semiautomatically and the metabolic tumor volume (MTV), mean standardized uptake value (SUVmean), maximum SUV (SUVmax) and integrated SUV (iSUV) were recorded. We analyzed whether IPS, absolute value PET parameters or the calculated ratio of interim- to pre-treatment PET parameters were associated with progression free survival (PFS) or overall survival (OS). Median follow-up of the study group was 50 months. Six of the 30 patients progressed clinically. Absolute value PET parameters from pre-treatment scans were not significant. Absolute value SUVmax from interim-treatment scans was associated with OS as determined by univariate analysis (p < 0.01). All four calculated PET parameters (interim/pre-treatment values) were associated with OS: MTV int/pre (p < 0.01), SUVmean int/pre (p < 0.05), SUVmax int/pre (p = 0.01), and iSUV int/pre (p < 0.01). Absolute value SUVmax from interim-treatment scans was associated with PFS (p = 0.01). Three calculated PET parameters (int/pre-treatment values) were associated with PFS: MTV int/pre (p = 0.01), SUVmax int/pre (p = 0.02) and iSUV int/pre (p = 0.01). IPS was associated with PFS (p < 0.05) and OS (p < 0.01). Calculated PET metrics may provide predictive information beyond that of traditional clinical factors and may identify patients at high risk of treatment failure early for treatment intensification

  19. Basis for Interim Operation for Fuel Supply Shutdown Facility

    International Nuclear Information System (INIS)

    BENECKE, M.W.

    2003-01-01

    This document establishes the Basis for Interim Operation (BIO) for the Fuel Supply Shutdown Facility (FSS) as managed by the 300 Area Deactivation Project (300 ADP) organization in accordance with the requirements of the Project Hanford Management Contract procedure (PHMC) HNF-PRO-700, ''Safety Analysis and Technical Safety Requirements''. A hazard classification (Benecke 2003a) has been prepared for the facility in accordance with DOE-STD-1027-92 resulting in the assignment of Hazard Category 3 for FSS Facility buildings that store N Reactor fuel materials (303-B, 3712, and 3716). All others are designated Industrial buildings. It is concluded that the risks associated with the current and planned operational mode of the FSS Facility (uranium storage, uranium repackaging and shipment, cleanup, and transition activities, etc.) are acceptable. The potential radiological dose and toxicological consequences for a range of credible uranium storage building have been analyzed using Hanford accepted methods. Risk Class designations are summarized for representative events in Table 1.6-1. Mitigation was not considered for any event except the random fire event that exceeds predicted consequences based on existing source and combustible loading because of an inadvertent increase in combustible loading. For that event, a housekeeping program to manage transient combustibles is credited to reduce the probability. An additional administrative control is established to protect assumptions regarding source term by limiting inventories of fuel and combustible materials. Another is established to maintain the criticality safety program. Additional defense-in-depth controls are established to perform fire protection system testing, inspection, and maintenance to ensure predicted availability of those systems, and to maintain the radiological control program. It is also concluded that because an accidental nuclear criticality is not credible based on the low uranium enrichment

  20. CERN Library | Tord Ekelöf presents the proceedings of the Nobel Symposium on the Higgs Boson Discovery and Other Recent LHC Results | 12 June

    CERN Multimedia

    2014-01-01

    Thursday, 12 June 2014 at 16:00 in the Library (52-1-052).   The “Nobel Symposium on LHC results” took place at Krusenberg mansion, Uppsala, Sweden on 13-17 May 2013. The aim of the Symposium was to give an overview of the latest experimental and theoretical results pertaining to the LHC programme but also to give an occasion to ponder over the implications of these results in the broader context of the past, present and future evolution of the field of Particle Physics. “Nobel Symposium 154: The Higgs Boson Discovery and Other Recent LHC Results”, ed. by Tord Ekelöf, Physica Scripta T154, IOP, 2013, ISBN 9789789789781. * Coffee will be served from 15:30 * E-proceedings available here.

  1. Gamma dose rate calculations for conceptual design of a shield system for spent fuel interim dry storage in CNA 1

    International Nuclear Information System (INIS)

    Blanco, A; Gomez S

    2012-01-01

    After completing the rearrangement of the Spent Fuel Elements (SFE) into a compact arrangement in the two storage water pools, Atucha Nuclear Reactor 1 (ANR 1) will leave free position for the wet storage of the SFE discharged until December 2014. Even, in two possible scenarios, such as extending operation from 2015 or the cessation of operation after that date, it will be necessary to empty the interim storage water pools transferring the SFE to a temporary dry storage system. Because the law 25.018 'Management of Radioactive Wastes' implies for the first scenario - operation beyond 2015 - that Nucleoelectrica Argentina S.A. will still be in charge of the dry storage system and for the second - the cessation of operation after 2015 - the National Commission of Atomic Energy (CNEA) will be in charge by the National Management Program of Radioactive Wastes, the interim dry storage system of SNF is an issue of common interest which justifies go forward together. For that purpose and in accordance with the criticality and shielding calculations relevant to the project, in this paper we present the dose rate calculations for shielding conceptual design of a system for dry interim storage of the SFE of ANR 1. The specifications includes that the designed system must be suitable without modification for the SFE of the ANR 2. The results for the calculation of the photon dose rate, in touch and at one meter far, for the Transport Module and the Container of the SFE, are presented, which are required and controlled by the National Regulatory Authority (NRA) and the International Atomic Energy Agency (IAEA). It was used the SAS4 module of SCALE5.1 system and MCNP5. As a design tool for the photon shielding in order to meet current standards for allowable dose rates, a radial and axial parametric analysis were developed based on the thickness of lead of the Transport Module. The results were compared and verified between the two computing systems. Before this

  2. Meet the Challenges of Spent Fuel Interim Storage by Using Intensive Innovation

    International Nuclear Information System (INIS)

    Garcia, J.; Compere, S.; Jung, O.

    2015-01-01

    stainless steel (BSS). The purpose of this paper is to present these experiences, and furthermore to underline our know-how and ability to provide highly efficient interim storage systems. (author)

  3. Present-day distribution and trends of global tropospheric ozone from satellite observations: Results from the Tropospheric Ozone Assessment Report (TOAR)

    Science.gov (United States)

    Gaudel, A.; Cooper, O. R.; Barret, B.; Boynard, A.; Clerbaux, C.; Pierre-Francois, C.; Huang, G.; Hurtmans, D.; Kerridge, B. J.; Latter, B.; Le Flochmoen, E.; Liu, X.; Neu, J. L.; Siddans, R.; Wespes, C.; Worden, H. M.; Ziemke, J. R.

    2017-12-01

    Tropospheric ozone is a greenhouse gas and pollutant detrimental to human health and crop and ecosystem productivity. Since 1990 a large portion of the anthropogenic emissions that react in the atmosphere to produce ozone have shifted from North America and Europe to Asia. This rapid shift, coupled with limited ozone monitoring in developing nations, has left scientists unable to answer the most basic questions: Is ozone continuing to decline in nations with strong emission controls? To what extent is ozone increasing in the developing world? IGAC's Tropospheric Ozone Assessment Report (TOAR) has been designed to answer these questions and this presentation will show the results from the TOAR-Climate initiative, focusing on the present-day distribution and trends of global tropospheric ozone from satellite observations. Five satellite products based on OMI (2 products using two different retrieval methods) and IASI (also 2 products using two different retrieval methods) and the OMI/MLS combined product were intercompared. An important result is the close agreement among the five products regarding the quantification of the total mass of all tropospheric ozone, the so called tropospheric ozone burden (TOB). The mean estimate for TOB between 60° N and 60° S is 296 Tg, with all products agreeing within ± 4%. However, on a regional basis the five satellite products have notable differences and there is no agreement in terms of ozone trends over the past decade. Continuing work is exploring the causes of these differences.

  4. Yucca Mountain socioeconomic project: An interim report on the State of Nevada socioeconomic studies

    International Nuclear Information System (INIS)

    1989-06-01

    The State of Nevada formally initiated a study of the socioeconomic impacts of a proposed high-level nuclear waste repository at Yucca Mountain in southern Nevada in 1986 after the Nevada site had been chosen as a potential waste disposal site. The State and affected local governments that participated in the development of the study recognized that the effort would need to go well beyond what is traditionally considered adequate for socioeconomic impact assessment because of the unique nature of the repository project. This Interim Report is a report on work in progress and presents findings from the research to date on the potential consequences of a repository for the citizens of Nevada. The research and findings in the Report have been subjected to rigorous peer review as part of the state's effort to insure independent, objective analysis that meets the highest professional standards. The basic research effort will continue through June 1990 and will enable the state to refine and clarify the findings presented in this Interim Report

  5. Alternatives for managing wastes from reactors and post-fission operations in the LWR fuel cycle. Volume 3. Alternatives for interim storage and transportation

    International Nuclear Information System (INIS)

    1976-05-01

    Volume III of the five-volume report contains information on alternatives for interim storage and transportation. Section titles are: interim storage of spent fuel elements; interim storage of chop-leach fuel bundle residues; tank storage of high-level liquid waste; interim storage of solid non-high-level wastes; interim storage of solidified high-level waste; and, transportation alternatives

  6. Alternatives for managing wastes from reactors and post-fission operations in the LWR fuel cycle. Volume 3. Alternatives for interim storage and transportation

    Energy Technology Data Exchange (ETDEWEB)

    1976-05-01

    Volume III of the five-volume report contains information on alternatives for interim storage and transportation. Section titles are: interim storage of spent fuel elements; interim storage of chop-leach fuel bundle residues; tank storage of high-level liquid waste; interim storage of solid non-high-level wastes; interim storage of solidified high-level waste; and, transportation alternatives. (JGB)

  7. Plutonium uranium extraction (PUREX) end state basis for interim operation (BIO) for surveillance and maintenance

    Energy Technology Data Exchange (ETDEWEB)

    DODD, E.N.

    1999-05-12

    This Basis for Interim Operation (BIO) was developed for the PUREX end state condition following completion of the deactivation project. The deactivation project has removed or stabilized the hazardous materials within the facility structure and equipment to reduce the hazards posed by the facility during the surveillance and maintenance (S and M) period, and to reduce the costs associated with the S and M. This document serves as the authorization basis for the PUREX facility, excluding the storage tunnels, railroad cut, and associated tracks, for the deactivated end state condition during the S and M period. The storage tunnels, and associated systems and areas, are addressed in WHC-SD-HS-SAR-001, Rev. 1, PUREX Final Safety Analysis Report. During S and M, the mission of the facility is to maintain the conditions and equipment in a manner that ensures the safety of the workers, environment, and the public. The S and M phase will continue until the final decontamination and decommissioning (D and D) project and activities are begun. Based on the methodology of DOE-STD-1027-92, Hazards Categorization and Accident Analysis Techniques for Compliance with DOE Order 5480.23, Nuclear Safety Analysis Reports, the final facility hazards category is identified as hazards category This considers the remaining material inventories, form and distribution of the material, and the energies present to initiate events of concern. Given the current facility configuration, conditions, and authorized S and M activities, there are no operational events identified resulting in significant hazard to any of the target receptor groups (e.g., workers, public, environment). The only accident scenarios identified with consequences to the onsite co-located workers were based on external natural phenomena, specifically an earthquake. The dose consequences of these events are within the current risk evaluation guidelines and are consistent with the expectations for a hazards category 2

  8. Hazelwood Interim Storage Site: Annual site environment report, Calendar year 1985

    International Nuclear Information System (INIS)

    1986-11-01

    The Hazelwood Interim Storage Site (HISS) is presently used for the storage of low-level radioactively contaminated soils. Monitoring results show that the HISS is in compliance with DOE Derived Concentration Guides (DCGs) and radiation protection standards. During 1985, annual average radon concentrations ranged from 10 to 23% of the DCG. The highest external dose rate at the HISS was 287 mrem/yr. The measured background dose rate for the HISS area is 99 mrem/yr. The highest average annual concentration of uranium in surface water monitored in the vicinity of the HISS was 0.7% of the DOE DCG; for 226 Ra it was 0.3% of the applicable DCG, and for 230 Th it was 1.7%. In groundwater, the highest annual average concentration of uranium was 12% of the DCG; for 226 Ra it was 3.6% of the applicable DCG, and for 230 Th it was 1.8%. While there are no concentration guides for stream sediments, the highest concentration of total uranium was 19 pCi/g, the highest concentration of 226 Ra was 4 pCi/g, and the highest concentration of 230 Th was 300 pCi/g. Radon concentrations, external gamma dose rates, and radionuclide concentrations in groundwater at the site were lower than those measured in 1984; radionuclide concentrations in surface water were roughly equivalent to 1984 levels. For sediments, a meaningful comparison with 1984 concentrations cannot be made since samples were obtained at only two locations and were only analyzed for 230 Th. The calculated radiation dose to the maximally exposed individual at the HISS, considering several exposure pathways, was 5.4 mrem, which is 5% of the radiation protection standard

  9. The effect of presenting information about invasive follow-up testing on individuals' noninvasive colorectal cancer screening participation decision: results from a discrete choice experiment.

    Science.gov (United States)

    Benning, Tim M; Dellaert, Benedict G C; Severens, Johan L; Dirksen, Carmen D

    2014-07-01

    Many national colorectal cancer screening campaigns have a similar structure. First, individuals are invited to take a noninvasive screening test, and, second, in the case of a positive screening test result, they are advised to undergo a more invasive follow-up test. The objective of this study was to investigate how much individuals' participation decision in noninvasive screening is affected by the presence or absence of detailed information about invasive follow-up testing and how this effect varies over screening tests. We used a labeled discrete choice experiment of three noninvasive colorectal cancer screening types with two versions that did or did not present respondents with detailed information about the possible invasive follow-up test (i.e., colonoscopy) and its procedure. We used data from 631 Dutch respondents aged 55 to 75 years. Each respondent received only one of the two versions (N = 310 for the invasive follow-up test information specification version, and N = 321 for the no-information specification version). Mixed logit model results show that detailed information about the invasive follow-up test negatively affects screening participation decisions. This effect can be explained mainly by a decrease in choice shares for the most preferred screening test (a combined stool and blood sample test). Choice share simulations based on the discrete choice experiment indicated that presenting invasive follow-up test information decreases screening participation by 4.79%. Detailed information about the invasive follow-up test has a negative effect on individuals' screening participation decisions in noninvasive colorectal cancer screening campaigns. This result poses new challenges for policymakers who aim not only to increase uptake but also to provide full disclosure to potential screening participants. Copyright © 2014 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

  10. Quantitative analyses at baseline and interim PET evaluation for response assessment and outcome definition in patients with malignant pleural mesothelioma

    Energy Technology Data Exchange (ETDEWEB)

    Lopci, Egesta; Chiti, Arturo [Humanitas Research Hospital, Nuclear Medicine Department, Rozzano, Milan (Italy); Zucali, Paolo Andrea; Perrino, Matteo; Gianoncelli, Letizia; Lorenzi, Elena; Gemelli, Maria; Santoro, Armando [Humanitas Research Hospital, Oncology, Rozzano (Italy); Ceresoli, Giovanni Luca [Humanitas Gavazzeni, Oncology, Bergamo (Italy); Giordano, Laura [Humanitas Research Hospital, Biostatistics, Rozzano (Italy)

    2015-04-01

    Quantitative analyses on FDG PET for response assessment are increasingly used in clinical studies, particularly with respect to tumours in which radiological assessment is challenging and complete metabolic response is rarely achieved after treatment. A typical example is malignant pleural mesothelioma (MPM), an aggressive tumour originating from mesothelial cells of the pleura. We present our results concerning the use of semiquantitative and quantitative parameters, evaluated at the baseline and interim PET examinations, for the prediction of treatment response and disease outcome in patients with MPM. We retrospectively analysed data derived from 131 patients (88 men, 43 women; mean age 66 years) with MPM who were referred to our institution for treatment between May 2004 and July 2013. Patients were investigated using FDG PET at baseline and after two cycles of pemetrexed-based chemotherapy. Responses were determined using modified RECIST criteria based on the best CT response after treatment. Disease control rate, progression-free survival (PFS) and overall survival (OS) were calculated for the whole population and were correlated with semiquantitative and quantitative parameters evaluated at the baseline and interim PET examinations; these included SUV{sub max}, total lesion glycolysis (TLG), percentage change in SUV{sub max} (ΔSUV{sub max}) and percentage change in TLG (ΔTLG). Disease control was achieved in 84.7 % of the patients, and median PFS and OS for the entire cohort were 7.2 and 14.3 months, respectively. The log-rank test showed a statistically significant difference in PFS between patients with radiological progression and those with partial response (PR) or stable disease (SD) (1.8 vs. 8.6 months, p < 0.001). Baseline SUV{sub max} and TLG showed a statistically significant correlation with PFS and OS (p < 0.001). In the entire population, both ΔSUV{sub max} and ΔTLG were correlated with disease control based on best CT response (p < 0

  11. Cost studies concerning decontamination and dismantling. The interim store for spent fuel at Studsvik; Kaerntekniska kostnadsstudier avseende dekontaminering och nedlaeggning. Mellanfoervaret foer anvaent kaernbraensle i Studsvik

    Energy Technology Data Exchange (ETDEWEB)

    Sjoeblom, Rolf; Sjoeoe, Cecilia [Tekedo AB, Nykoeping (Sweden); Lindskog, Staffan; Cato, Anna [Swedish Nuclear Power Inspectorate, Stockholm (Sweden)

    2006-04-15

    The interim store for spent fuel at Studsvik was designed and constructed in 1962-64. It has been used for wet storage of fuel from the Aagesta Nuclear Power Plant as well as the R2 reactor at Studsvik. The interim store comprises three cylindrical pools for fuel storage as well as equipment for handling and decontamination. The purpose of the present work is to develop methodology for calculation of future costs for decontamination and dismantling of nuclear research facilities. The analysis is based on information from Studsvik as well as results from information searches. The requirements on precision of cost calculations is high, also at early stages. The reason for this is that the funds are to be collected now but are to be used some time in the future. At the same time they should neither be insufficient nor superfluous. It is apparent from the compilation and analysis that when methodology that has been developed for the purpose of cost calculations for power reactors is applied to research facilities certain drawbacks become apparent, e.g. difficulties to carry out variation analyses. Generally, feedback of data on incurred costs for the purpose of cost calculations can be achieved by using one or more scaling factors together with weighing factors which are established based on e.g. expert judgement. For development and utilisation of such tools it is necessary to have access to estimated costs together with incurred ones. In the report, the following combination of aspects is identified as being of primary significance for achieving a high precision: Calculations with the possibility to calibrate against incurred costs; Radiological surveying tailored to the needs for calculations; Technical planning including selection of techniques to be used; Identification of potential sources for systematic deviations. In the case of the interim store, some of the sources of uncertainty are as follows: Damaged surface layers in the pools; Maintenance status for the

  12. Safety Consideration for a Wet Interim Spent Fuel Store at Conceptual Design Stage

    International Nuclear Information System (INIS)

    Astoux, Marion

    2014-01-01

    EDF Energy plans to build and operate two UK EPRs at the Hinkley Point C (HPC) site in Somerset, England. Spent fuel from the UK EPRs will need to be managed from the time it is discharged from the reactor until it is ultimately disposed of and this will involve storing the spent fuel for a period in the fuel building and thereafter in a dedicated interim facility until it can be emplaced within the UK Geological Disposal Facility. EDF Energy has proposed that this interim store should be located on the Hinkley Point site which is consistent with UK policy. This Interim Spent Fuel Store (ISFS) will have the capability to store for at least one hundred years the spent fuel arising from the operation of the two EPR units (sixty years operation). Therefore, specificities regarding the lifetime of the facility have to be accounted for its design. The choice of interim storage technology was considered in some depth for the HPC project and wet storage (pool) was selected. The facility is currently at conceptual design stage, although its construction will be part of main site construction phase. Safety functions and safety requirements for this storage facility have been defined, in compliance with WENRA 'Waste and Spent Fuel Storage - Safety Reference Level Report' and IAEA Specific Safety Guide no. 15 'Storage of Spent Nuclear Fuel'. EDF technical know-how, operational feedback on existing storage pools, UK regulatory context and Fukushima experience feedback have also been accounted for. Achievement of the safety functions as passively as reasonably practicable is a key issue for the design, especially in accident situations. Regarding lifetime aspects, ageing management of equipments, optimisation of the refurbishment, climate change, passivity of the facility, and long-term achievement of the safety functions are among the subjects to consider. Adequate Operational Limits and Conditions will also have to be defined, to enable the long-term achievement of the safety

  13. Interim design report: fuel particle crushing

    International Nuclear Information System (INIS)

    Baer, J.W.; Strand, J.B.; Cook, E.J.; Miller, C.M.

    1977-11-01

    The double-roll fuel particle crusher was developed to fracture the silicon carbide coatings of Fort St. Vrain (FSV) fertile and fissile and large high-temperature gas-cooled reactor (LHTGR) fissile fuel particles. The report details the design task for the fuel particle crusher, including historical test information on double-roll crushers for carbide-coated fuels and the design approach selected for the cold pilot plant crusher, and shows how the design addresses the equipment goals and operational objectives. Design calculations and considerations are included to support the selection of crusher drive and gearing, the materials chosen for crushing rolls and housing, and the bearing selection. The results of the initial testing for compliance with design objectives and operational capabilities are also presented. 8 figures, 4 tables

  14. The barriers to accessing primary care resulting in hospital presentation for exacerbation of asthma or chronic obstructive pulmonary disease in a large teaching hospital in London.

    Science.gov (United States)

    Naqvi, Marium; Khachi, Hasanin

    2016-08-01

    Asthma and chronic obstructive pulmonary disease (COPD) account direct costs of £1 billion each per year in the United Kingdom (UK). A national review of asthma deaths found that a significant proportion of patients die without seeking medical assistance or before emergency medical care could be provided. This study aims to establish the pathway that patients undertake to access care in the lead up to an accident and emergency (A&E) attendance and/or inpatient admission. Patients attending A&E and/or following an inpatient admission due to an exacerbation of asthma or COPD were reviewed by a specialist respiratory pharmacist during weekday working hours. Over a one-year period, 920 (224 asthma and 696 COPD) presentations for exacerbation of asthma and COPD were reviewed. Although the majority of the patients were registered with a general practitioner (GP), less than 50% received medical attention from their GP and/or had an active intervention prior to presenting to hospital. These findings correlate with those found in the national review of asthma deaths. At a time of increasing demands on healthcare resources, these results pose the question of how we can better triage patients to appropriate care settings to minimise unscheduled care and improve patient outcomes. Crown Copyright © 2016. Published by Elsevier Ltd. All rights reserved.

  15. [The results of the combined application of extracorporeal shock-wave therapy and radon baths during the rehabilitative treatment of the patients presenting with gonarthrosis].

    Science.gov (United States)

    Razumov, A N; Puriga, A O; Yurova, O V

    2015-01-01

    Osteoarthritis (OA) is one of the leading diseases of the musculoskeletal system and the main cause of arthritic joint damage. The objective of the present study was to evaluate the effectiveness of the combined application of radon baths and shock-wave therapy in the patients suffering from knee OA. The study involved 75 patients at the age of 35 to 62 years with the confirmed diagnosis of stage II and III gonarthrosis; they were divided into 3 groups. The patients of the main group received the combined treatment including extracorporeal shock-wave therapy and radon baths The patients comprising the group of comparison were given the course of radon therapy alone while those in the control group were offered the standard treatment including physiotherapy, magnetic therapy, and NSAIDs. The study has demonstrated the high effectiveness of the combined application of the radon baths and extracorporeal shock-wave therapy for the rehabilitation of the patients with deforming arthrosis of the knee that was apparent from the substantial decrease of pain syndrome, the increase of the range of motions in the knee joints, and the overall improvement of the quality of life. These beneficial changes persisted for a period of up to 6 months. The results of the present study give reason to recommend the proposed method of the remedial treatment for the wide practical application as a component in the framework of the medical rehabilitation programs.

  16. Single-trial detection of event-related fields in MEG from the presentation of happy faces: Results of the Biomag 2016 data challenge.

    Science.gov (United States)

    Cecotti, H; Barachant, A; King, J R; Sanchez Bornot, J; Prasad, G

    2017-07-01

    The recognition of brain evoked responses at the single-trial level is a challenging task. Typical non-invasive brain-computer interfaces based on event-related brain responses use eletroencephalograhy. In this study, we consider brain signals recorded with magnetoencephalography (MEG), and we expect to take advantage of the high spatial and temporal resolution for the detection of targets in a series of images. This study was used for the data analysis competition held in the 20th International Conference on Biomagnetism (Biomag) 2016, wherein the goal was to provide a method for single-trial detection of even-related fields corresponding to the presentation of happy faces during the rapid presentation of images of faces with six different facial expressions (anger, disgust, fear, neutrality, sadness, and happiness). The datasets correspond to 204 gradiometers signals obtained from four participants. The best method is based on the combination of several approaches, and mainly based on Riemannian geometry, and it provided an area under the ROC curve of 0.956±0.043. The results show that a high recognition rate of facial expressions can be obtained at the signal-trial level using advanced signal processing and machine learning methodologies.

  17. The determination of the cesium distribution coefficient of the interim storage soil from Abadia de Goias, Go, Brazil

    International Nuclear Information System (INIS)

    Marumo, J.T.; Suarez, A.A.

    1989-01-01

    In September, 1987, an unauthorized removal of a cesium-therapy unit and its violation caused an accident, where several places of Goiania's city, capital of Goias, Brazil, were contaminated. The removal of the radioactive wastes generated from decontamination process, was made to Abadia de Goias city (near Goiania), where an interim storage was constructed. Soil samples collected from the 57th Street (Goiania) and from the interim storage permitted to determine, through static method, the cesium distribution coefficient for different cesium solution concentrations. Those results allows for some migration/retention evaluations in disposal site selection. Some soils parameters (water content, density, granulometric analysis, etc) as well as clay minerals constituents were also determined. (author) [pt

  18. Wayne Interim Storage Site environmental report for calendar year 1989, Wayne, New Jersey

    International Nuclear Information System (INIS)

    1990-05-01

    The environmental monitoring program, begun in 1984, was continued in 1989 at the Wayne Interim Storage Site (WISS), a US Department of Energy (DOE) facility located in Wayne Township, New Jersey. The WISS is part of the Formerly Utilized Sites Remedial Action Program (FUSRAP), a DOE program to decontaminate or otherwise control sites where residual radioactive material remains from the early years of the nation's atomic energy program or from commercial operations causing conditions that Congress has authorized DOE to remedy. The monitoring program at WISS measures radon and thoron concentrations in air; external gamma radiation levels; and uranium, radium, and thorium concentrations in surface water, groundwater, and sediment. Additionally, several nonradiological parameters are measured in groundwater. The radiation dose was calculated for a hypothetical maximally exposed individual to verify that the site is in compliance with the DOE radiation protection standard (100 mrem/yr) and to assess its potential effects on public health. This report presents the findings of the environmental monitoring program conducted at the Wayne Interim Storage Site (WISS) during calendar year 1989. 26 refs., 12 figs., 16 tabs

  19. Cna 1 spent fuel element interim dry storage system thermal analysis

    International Nuclear Information System (INIS)

    Hilal, R. E; Garcia, J. C; Delmastro, D. F

    2006-01-01

    At the moment, the Atucha I Nuclear Power Plant (Cnea-I) located in the city of Lima, has enough room to store its spent fuel (Sf) in their two pools spent fuel until about 2015.In case of life extension a spend fuel element interim dry storage system is needed.Nucleolectrica Argentina S.A. (N A-S A) and the Comision Nacional de Energia Atomica (Cnea), have proposed different interim dry storage systems.These systems have to be evaluated in order to choose one of them.The present work's objective is the thermal analysis of one dry storage alternative for the Sf element of Cna 1.In this work a simple model was developed and used to perform the thermal calculations corresponding to the system proposed by Cnea.This system considers the store of sealed containers with 37 spent fuels in concrete modules.Each one of the containers is filled in the pool houses and transported to the module in a transference cask with lead walls.Fulfill the maximum cladding temperature requirement ( [es

  20. INTERIM STORAGE AND LONG TERM DISPOSAL OF RESEARCH REACTOR SPENT FUEL

    Energy Technology Data Exchange (ETDEWEB)

    Vinson, D

    2006-08-22

    Aluminum clad research reactor spent nuclear fuel (SNF) is currently being consolidated in wet storage basins (pools). Approximately 20 metric tons (heavy metal) of aluminum-based spent nuclear fuel (Al-SNF) is being consolidated for treatment, packaging, interim storage, and preparation for ultimate disposal in a geologic repository. The storage and disposal of Al-SNF are subject to requirements that provide for safety and acceptable radionuclide release. The options studied for interim storage of SNF include wet storage and dry storage. Two options have also been studied to develop the technical basis for the qualification and repository disposal of aluminum spent fuel. The two options studied include Direct Disposal and Melt-Dilute treatment. The implementation of these options present relative benefits and challenges. Both the Direct Disposal and the Melt-Dilute treatment options have been developed and their technical viability assessed. Adaptation of the melt-dilute technology for the treatment of spent fuel offers the benefits of converting the spent fuel into a proliferation resistant form and/or significantly reducing the volume of the spent fuel. A Mobile Melt-Dilute system concept has emerged to realize these benefits and a prototype system developed. The application of the melt-dilute technology for the treatment of legacy nuclear materials has been evaluated and also offers the promise for the safe disposal of these materials.

  1. Energy policy act transportation study: Interim report on natural gas flows and rates

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-11-17

    This report, Energy Policy Act Transportation Study: Interim Report on Natural Gas Flows and Rates, is the second in a series mandated by Title XIII, Section 1340, ``Establishment of Data Base and Study of Transportation Rates,`` of the Energy Policy Act of 1992 (P.L. 102--486). The first report Energy Policy Act Transportation Study: Availability of Data and Studies, was submitted to Congress in October 1993; it summarized data and studies that could be used to address the impact of legislative and regulatory actions on natural gas transportation rates and flow patterns. The current report presents an interim analysis of natural gas transportation rates and distribution patterns for the period from 1988 through 1994. A third and final report addressing the transportation rates and flows through 1997 is due to Congress in October 2000. This analysis relies on currently available data; no new data collection effort was undertaken. The need for the collection of additional data on transportation rates will be further addressed after this report, in consultation with the Congress, industry representatives, and in other public forums.

  2. Does the radiation from the interim storage in Gorleben affect the sex ratio of newborn children?

    International Nuclear Information System (INIS)

    Engelmann, H.W.; Schulze, H.; Wede, S.; Mueller, S.

    2015-01-01

    In the professional world but especially in public, the question is discussed whether ionizing radiation from nuclear facilities has a significant impact on the secondary sex ratio of newborn children in the vicinity of the plants. This issue is of exceptional importance in the region around Gorleben, where the opposition to nuclear facilities and activities for decades is particularly strong. At the site borders of the interim storage facility (TBL-G) of GNS the effective individual dose is about 0.2 mSv per year, mainly caused by neutron irradiation from 108 casks with high-level radioactive waste from reprocessing. In the surrounding villages there is no radiation measurable. Statistical studies allegedly have shown evidence that in some villages in the area and during certain periods, proportionately fewer girls were born in comparison to the average for the Federal Republic of Germany. Based on these purely statistical results henceforward was also alleged that neutron-induced secondary effects such as activation or secondary gamma radiation would be responsible for it. Monte Carlo calculations and special measurements yielded values of the dose at the plant border for activation products less than E-04 mSv/a and for secondary gamma radiation of about E-03 mSv/a. These results indicate that the ionizing radiation from the Gorleben interim storage facility cannot be held accountable for shifts of the secondary sex ratio.

  3. Interim safety basis compliance matrix for Trenches 31 and 34

    International Nuclear Information System (INIS)

    Ames, R.R.

    1994-01-01

    The tables provided in this document identify the specific requirements and basis for the administrative controls established in the Westinghouse Hanford Company (WHC) Solid Waste Burial Ground (SWBG) Interim Safety Basis (ISB) for operation of the Project W-025, Mixed Waste Lined Landfill (Trenches 31 and 34). The tables document the necessary controls and implementing procedures to ensure compliance with the requirements of the ISB. These requirements provide a basis for future Unreviewed Safety Questions (USQ) screening of applicable procedure changes, proposed physical modifications, tests, experiments, and occurrences. Table 1 provides the SWBG interim Operational Safety Requirements administrative controls matrix. The specific assumptions and commitments used in the safety analysis documents applicable to disposal of mixed wastes in Trenches 31 and 34 are provided in Table 2. Table 3 is provided to document the potential engineered and administrative mitigating features identified in the Preliminary Hazard Analysis (PHA) for disposal of mixed waste

  4. 105-C Reactor interim safe storage project technology integration plan

    International Nuclear Information System (INIS)

    Pulsford, S.K.

    1997-01-01

    The 105-C Reactor Interim Safe Storage Project Technology Integration Plan involves the decontamination, dismantlement, and interim safe storage of a surplus production reactor. A major goal is to identify and demonstrate new and innovative D and D technologies that will reduce costs, shorten schedules, enhance safety, and have the potential for general use across the RL complex. Innovative technologies are to be demonstrated in the following areas: Characterization; Decontamination; Waste Disposition; Dismantlement, Segmentation, and Demolition; Facility Stabilization; and Health and Safety. The evaluation and ranking of innovative technologies has been completed. Demonstrations will be selected from the ranked technologies according to priority. The contractor team members will review and evaluate the demonstration performances and make final recommendations to DOE

  5. Rehabilitation of failing dentition with interim immediate denture prosthesis

    Directory of Open Access Journals (Sweden)

    Amit Sharma

    2016-01-01

    Full Text Available Advances in therapy have helped patients with periodontal disease to retain part of their natural dentition for an extended period. These patients can be well served by properly designed removable partial dentures. For the patient facing the loss of all his/her remaining natural teeth, there are three treatment options. One is for the patient to have all remaining teeth extracted and wait for 6–8 weeks for the extraction sites to heal. The conventional complete denture is made following healing, leaving the patient without teeth not only during the healing phase but also during the time required for the fabrication of the conventional complete denture. A second option is to convert an existing removable partial denture into an interim immediate complete denture. A third option is to make a conventional immediate complete denture. The aim of this clinical report was to describe the fabrication of interim immediate denture in a patient with hopeless existing dentition.

  6. Conservative treatment of idiopathic scoliosis according to FITS concept: presentation of the method and preliminary, short term radiological and clinical results based on SOSORT and SRS criteria

    Science.gov (United States)

    2011-01-01

    Background Conservative scoliosis therapy according to the FITS Concept is applied as a unique treatment or in combination with corrective bracing. The aim of the study was to present author's method of diagnosis and therapy for idiopathic scoliosis FITS-Functional Individual Therapy of Scoliosis and to analyze the early results of FITS therapy in a series of consecutive patients. Methods The analysis comprised separately: (1) single structural thoracic, thoracolumbar or lumbar curves and (2) double structural scoliosis-thoracic and thoracolumbar or lumbar curves. The Cobb angle and Risser sign were analyzed at the initial stage and at the 2.8-year follow-up. The percentage of patients improved (defined as decrease of Cobb angle of more than 5 degrees), stable (+/- 5 degrees), and progressed (increase of Cobb angle of more than 5 degrees) was calculated. The clinical assessment comprised: the Angle of Trunk Rotation (ATR) initial and follow-up value, the plumb line imbalance, the scapulae level and the distance from the apical spinous process of the primary curve to the plumb line. Results In the Group A: (1) in single structural scoliosis 50,0% of patients improved, 46,2% were stable and 3,8% progressed, while (2) in double scoliosis 50,0% of patients improved, 30,8% were stable and 19,2% progressed. In the Group B: (1) in single scoliosis 20,0% of patients improved, 80,0% were stable, no patient progressed, while (2) in double scoliosis 28,1% of patients improved, 46,9% were stable and 25,0% progressed. Conclusion Best results were obtained in 10-25 degrees scoliosis which is a good indication to start therapy before more structural changes within the spine establish. PMID:22122964

  7. 105-H Reactor Interim Safe Storage Project Final Report

    International Nuclear Information System (INIS)

    Ison, E.G.

    2008-01-01

    The following information documents the decontamination and decommissioning of the 105-H Reactor facility, and placement of the reactor core into interim safe storage. The D and D of the facility included characterization, engineering, removal of hazardous and radiologically contaminated materials, equipment removal, decontamination, demolition of the structure, and restoration of the site. The ISS work also included construction of the safe storage enclosure, which required the installation of a new roofing system, power and lighting, a remote monitoring system, and ventilation components.

  8. Gender Issues and Social Science Education - An Interim Report

    OpenAIRE

    Mechthild Oechsle; Karin Wetterau

    2005-01-01

    This article discusses the relevance of gender issues for social science education and gives an interim report on developments in the field. We explore the significance of gender differences in political attitudes and preferences for certain topics of instruction, consider differences in the learning needs of male and female students, and analyse the curricular challenges involved in incorporating the gender perspective in the classroom. Deficits in the curricular coverage of gender issues re...

  9. In vitro resistance of reinforced interim fixed partial dentures.

    Science.gov (United States)

    Pfeiffer, Peter; Grube, Lars

    2003-02-01

    Comprehensive restorative dental treatment often necessitates the use of interim fixed partial dentures (FPDs) with high stiffness, especially in long-span restorations or areas of heavy occlusal stress. This in vitro study evaluated the fracture load of interim FPDs made with various materials and span lengths. Groups (n = 3) of interim FPDs were fabricated with prosthodontic resin materials on 2 abutments with 3 different pontic widths of 3 units (12 mm), 4 units (19 mm), and 5 units (30 mm). The following materials were tested: (1) a thermoplastic polymer (Promysan Star), (2) Promysan Star with a veneering composite (Vita Zeta), (3) a nonimpregnated polyethylene fiber reinforced resin (Ribbond) with a veneering composite (Sinfony), (4) an impregnated fiber reinforced composite system (Targis/Vectris), and (5) a conventional polymethyl methacrylate, Biodent K+B, (control group). After 5000 thermocycles in 2 water baths at 5 degrees and 55 degrees C, the FPDs were temporarily fixed with a provisional cement on the corresponding abutments and subjected to 3-point bending until fracture by a universal testing machine. Statistical analysis consisted of an analysis of variance (ANOVA, 1-way, 2-way) and Bonferroni-Dunn's multiple comparisons post hoc analysis for test groups (alpha = .05). Fracture resistance (N) differed significantly for 3 (mean: 640 +/- 146 N), 4 (626 +/- 229 N), and 5 unit (658 +/- 98 N) Targis/Vectris FPDs compared with the corresponding Promysan (284 +/- 21 N to 125 +/- 73 N), Biodent K+B (247 +/- 91 N to 218 +/- 85 N), and Promysan/Vita Zeta (95 +/- 15 N to 82 +/- 6 N) groups (P < .05). Significant differences were obtained for the 4 and 5 unit Targis/Vectris FPDs compared with the Sinfony/Ribbond FPDs (281 +/- 25 N - 252 +/- 74 N) for the corresponding pontic spans. Within the limitations of this in vitro study the impregnated fiber reinforcement may considerably enhanced the fracture resistance of interim FPDs of different span lengths.

  10. Interim Sanitary Landfill Groundwater Monitoring Report. 1997 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-01-01

    Eight wells of the LFW series monitor groundwater quality in the Steed Pond Aquifer (Water Table) beneath the Interim Sanitary Landfill at the Savannah River Site (SRS). These wells are sampled semiannually to comply with the South Carolina Department of Health and Environmental Control Modified Municipal Solid Waste Permit 025500-1120 (formerly dWP-087A) and as part of the SRS Groundwater Monitoring Program.

  11. Interim Stabilization Equipment Essential and Support Drawing Plan

    International Nuclear Information System (INIS)

    HORNER, T.M.

    2000-01-01

    The purpose of this document is to list the Interim Stabilization equipment drawings that are classified as Essential or Support drawings. Essential Drawings are those drawings identified by the facility staff as necessary to directly support the safe operation of the facility or equipment. [CHG 2000a]. Support Drawings are those drawings identified by the facility staff that further describe the design details of structures, systems or components shown on essential drawings. [CHG 2000a

  12. Interim Stabilization Equipment Essential and Support Drawing Plan

    International Nuclear Information System (INIS)

    KOCH, M.R.

    1999-01-01

    The purpose of this document is to list the Interim Stabilization equipment drawings that are classified as Essential or Support drawings. Essential Drawings: Those drawings identified by the facility staff as necessary to directly support the safe operation of the facility or equipment. Support Drawings: Those drawings identified by the facility staff that further describe the design details of structures, systems or components shown on essential drawings

  13. FRACTIONAL CRYSTALLIZATION TESTING WITH INTERIM PRETREATMENT SYSTEM FEEDS

    International Nuclear Information System (INIS)

    HERTING DL

    2008-01-01

    The fractional crystallization process was developed as a pretreatment method for saltcake waste retrieved from Hanford single-shell tanks (SST). The process separates the retrieved SST waste into a high-level waste stream containing the bulk of the radionuclides and a low-activity waste stream containing the bulk of the nonradioactive sodium salts. The Interim Pretreatment System project shifted the focus on pretreatment planning from SST waste to double-shell tank waste

  14. 105-H Reactor Interim Safe Storage Project Final Report

    Energy Technology Data Exchange (ETDEWEB)

    E.G. Ison

    2008-11-08

    The following information documents the decontamination and decommissioning of the 105-H Reactor facility, and placement of the reactor core into interim safe storage. The D&D of the facility included characterization, engineering, removal of hazardous and radiologically contaminated materials, equipment removal, decontamination, demolition of the structure, and restoration of the site. The ISS work also included construction of the safe storage enclosure, which required the installation of a new roofing system, power and lighting, a remote monitoring system, and ventilation components.

  15. Fluoride ion release and solubility of fluoride enriched interim cements.

    Science.gov (United States)

    Lewinstein, Israel; Block, Jonathan; Melamed, Guy; Dolev, Eran; Matalon, Shlomo; Ormianer, Zeev

    2014-08-01

    Interim and definitive restorations cemented with interim cements for a prolonged interval are susceptible to bacterial infiltration and caries formation. The purpose of this in vitro study was to evaluate the long-term fluoride release and solubility of aged ZnO-based interim cements enriched separately with 0.4% NaF and SnF2. Four different brands of cements (Tempbond, Tempbond NE, Procem, and Freegenol) were tested for fluoride release and solubility. For every test, 6 disk specimens of each cement with NaF and SnF2, and 6 with no fluoride enrichment (control) were fabricated, for a total of 72 specimens. The disks were incubated in deionized water. Fluoride ion release was recorded at 1, 7, 14, 21, 63, 91, and 182 days. Solubility was calculated as weight percent after 90 days of incubation. The data were analyzed by analysis of variance with repeated measures and the Tukey honestly significant difference post hoc test (Pfluorides released fluoride ions for at least 182 days. Cements mixed with NaF released more fluoride ions than those mixed with SnF2 (P.97), indicating a diffusion-controlled fluoride release. Cement and fluoride types were the main affecting factors in fluoride ion release. The addition of fluorides slightly increased the solubility of the cements. Given their long-term sustained and diffusive controlled release, these fluorides, particularly NaF when mixed with ZnO-based interim cements, may be useful for caries prevention under provisionally cemented restorations. Copyright © 2014 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

  16. Interim dry storage system technologies and innovations VARNA 2002

    International Nuclear Information System (INIS)

    Chollet, P.; Guenon, Y.

    2002-01-01

    The main concepts of the TN24 Family and NUHOMS System are explained in the paper. It is discussed how the NPPs specific requirements and economics trends contributes to the growing families of interim dry storage systems delivered under COGEMA LOGICTICS license. It is concluded that modular solutions are currently dominating because they are derived from main concepts evolved over time, benefited from both the transport aspects with internationally recognised stringent regulations, and various specific ISFSI requirements and economic trends

  17. Waste Encapsulation and Storage Facility interim operational safety requirements

    CERN Document Server

    Covey, L I

    2000-01-01

    The Interim Operational Safety Requirements (IOSRs) for the Waste Encapsulation and Storage Facility (WESF) define acceptable conditions, safe boundaries, bases thereof, and management or administrative controls required to ensure safe operation during receipt and inspection of cesium and strontium capsules from private irradiators; decontamination of the capsules and equipment; surveillance of the stored capsules; and maintenance activities. Controls required for public safety, significant defense-in-depth, significant worker safety, and for maintaining radiological consequences below risk evaluation guidelines (EGs) are included.

  18. Interim reliability evaluation program, Browns Ferry fault trees

    International Nuclear Information System (INIS)

    Stewart, M.E.

    1981-01-01

    An abbreviated fault tree method is used to evaluate and model Browns Ferry systems in the Interim Reliability Evaluation programs, simplifying the recording and displaying of events, yet maintaining the system of identifying faults. The level of investigation is not changed. The analytical thought process inherent in the conventional method is not compromised. But the abbreviated method takes less time, and the fault modes are much more visible

  19. Explicit feedback to enhance the effect of an interim assessment: a cross-over study on learning effect and gender difference

    NARCIS (Netherlands)

    Olde Bekkink, M.; Donders, R.; van Muijen, G.N.; de Waal, R.M.; Ruiter, D.J.

    2012-01-01

    In a previous study we demonstrated by a prospective controlled design that an interim assessment during an ongoing small group work (SGW) session resulted in a higher score in the course examination. As this reflects the so-called testing effect, which is supposed to be enhanced by feedback, we

  20. Resultados de la ileocistoplastia ortotópica en pacientes con tumor vesical Orthotopic ileocystoplasty results in patient presenting vesical tumor

    Directory of Open Access Journals (Sweden)

    Adolfo García García

    2010-03-01

    Full Text Available INTRODUCCIÓN. El cáncer de la vejiga es considerado un problema de salud tanto en Cuba como en el mundo. La cistectomía radical y sus variantes terapéuticas tienen la finalidad de curar o controlar la enfermedad, y conllevan la creación de un reservorio lo más semejante posible a la vejiga, por lo que se trabaja en la creación y perfeccionamiento de neovejigas a partir de un segmentointestinal. El objetivo de esta investigación fue evaluar los resultados de la ileocistoplastia ortotópica como procedimiento derivativo de la orina, después de la cistectomía total. MÉTODOS. Se realizó un estudio descriptivo, retrospectivo y prospectivo de 40 pacientes tratados en el Hospital «Hermanos Ameijeiras», en La Habana, entre los años 2000 y 2008. La fuente de información fueron los expedientes clínicos de los pacientes, y los datos se procesaron por medios automatizados. RESULTADOS. La mayor incidencia se encontró en los pacientes con 65 años de edad. La enuresis fue la forma de incontinencia urinaria que predominó y la mayoría de los pacientes tenían micciones voluntarias. Siete pacientes presentaron hidronefrosis y las fístulas del reservorio se relacionaron con la radioterapia. La mortalidad fue del 7,5 %. CONCLUSIONES. La ileocistoplastia ortotópica es un sustituto vesical aceptable en los pacientes con tumores vesicales.INTRODUCTION: The bladder cancer is considered a health problem in Cuba and worldwide. The aim of radical cystectomy and its therapeutical variants is to cure or control the disease and it is necessary the creation of a reservoir very similar to bladder and nowadays it is working in creation and improvement of the neo-bladders from an intestinal segment. The aim of present research was to assess the orthotopic ileocystoplasty results as urine derivative procedure after total cystectomy. METHODS: A prospective, retrospective and descriptive study was conducted in 40 patients seen in "Hermanos Ameijeiras

  1. The Interim Financial Reporting in the Spirit of the IAS 34 Norm

    OpenAIRE

    Ovidia Doinea

    2008-01-01

    The role of an interim financial reporting is to allow the information users to acknowledge the activity of an entity on period shorter than financial exercise from the perspective of the available profits and cash flows generated as well as from the point of view of its financial position and liquidity. The interim financial reporting includes a complete or condensed set of financial statements which target to update the last financial reporting, usually the annual report. The interim financ...

  2. Interim guidelines for protecting fire-fighting personnel from multiple hazards at nuclear plant sites

    International Nuclear Information System (INIS)

    Klein, A.R.; Bloom, C.W.

    1989-07-01

    This report provides interim guidelines for reducing the impact to fire fighting and other supporting emergency response personnel from the multiple hazards of radiation, heat stress, and trauma when fighting a fire in a United States commercial nuclear power plant. Interim guidelines are provided for fire brigade composition, training, equipment, procedures, strategies, heat stress and trauma. In addition, task definitions are provided to evaluate and further enhance the interim guidelines over the long term. 19 refs

  3. Effect of polyester fiber reinforcement on the mechanical properties of interim fixed partial dentures

    OpenAIRE

    Gopichander, N.; Halini Kumarai, K.V.; Vasanthakumar, M.

    2015-01-01

    Background: Different reinforcements currently available for interim fixed partial denture (FPD) materials do not provide the ideal strength for long-term use. Therefore, the aim of this investigation was to develop a more ideal provisional material for long-term use with better mechanical properties. This study evaluated the effectiveness of polyester fiber reinforcement on different interim FPD materials. Methods: Thirty resin-bonded FPDs were constructed from three provisional interim F...

  4. ZINC MITIGATION INTERIM REPORT - THERMODYNAMIC STUDY

    Energy Technology Data Exchange (ETDEWEB)

    Korinko, P.

    2010-12-17

    An experimental program was initiated in order to develop and validate conditions that will effectively trap Zn vapors that are released during extraction. The proposed work is broken down into three tasks. The first task is to determine the effectiveness of various pore sizes of filter elements. The second task is to determine the effect of filter temperature on zinc vapor deposition. The final task is to determine whether the zinc vapors can be chemically bound. The approach for chemically binding the zinc vapors has two subtasks, the first is a review of literature and thermodynamic calculations and the second is an experimental approach using the best candidates. This report details the results of the thermodynamic calculations to determine feasibility of chemically binding the zinc vapors within the furnace module, specifically the lithium trap (1). A review of phase diagrams, literature, and thermodynamic calculations was conducted to determine if there are suitable materials to capture zinc vapor within the lithium trap of the extraction basket. While numerous elements exist that form compounds with zinc, many of these also form compounds with hydrogen or the water that is present in the TPBARs. This relatively comprehensive review of available data indicates that elemental cobalt and copper and molybdenum trioxide (MoO3) may have the requisite properties to capture zinc and yet not be adversely affected by the extraction gases and should be considered for testing.

  5. African-American (AA) men with local-regional prostate cancer (PC) present with higher prostate specific antigen (PSA) levels than whites: results of RTOG 94-12

    International Nuclear Information System (INIS)

    Vijayakumar, S.; Winter, K.; Sause, W.; Gallagher, M.J.; Perez, C.; Bondy, M.

    1996-01-01

    Purpose/Objective: To use pretreatment serum PSA levels as an 20), gleason score (2-5,6-7,7-10), race (whites and AAs), and two interactions viz (a) PSA by race (p=0.0012) and (b) PSA by total gleason score (p=0.0001). When race was replaced by educational status, or income, or both, the fits (0.8246,0.8197, and 0.7815, respectively) were not as good as the fit with race in the model. Conclusion: The findings of this nation-wide prospective registration study with a high percentage of AA patient participation confirms previous, smaller, geographically-limited studies (1,2,3) results that AA patients with non-metastatic PC present with a higher mean PSA values than whites. The multivariate findings imply that, for each level of total gleason score, there is a higher percentage of whites with PSA levels 20. Education and/or income as surrogates of sociological status could not completely explain the racial differences. Other reasons for health-care barriers among AAs need to be identified

  6. Interim policy on establishment and operation of internet open, anonymous information servers and services

    OpenAIRE

    Acting Dean of Computer and Information Services

    1995-01-01

    Purpose. To establish interim NPS general policy regarding establishment and operation of Open, Anonymous Information Servers and Services, such as World Wide Web (http), Gopher, Anonymous FTP, etc...

  7. Methods for assessing environmental impacts of a FUSRAP property-cleanup/interim-storage remedial action

    International Nuclear Information System (INIS)

    Wyman, D.J.

    1982-12-01

    This document provides a description of a property-cleanup/interim-storage action, explanation of how environmental impacts might occur, comprehensive treatment of most potential impacts that might occur as a result of this type of action, discussion of existing methodologies for estimating and assessing impacts, justification of the choice of specific methodologies for use in FUSRAP environmental reviews, assessments of representative impacts (or expected ranges of impacts where possible), suggested mitigation measures, and some key sources of information. The major topical areas covered are physical and biological impacts, radiological impacts, and socioeconomic impacts. Some project-related issues were beyond the scope of this document, including dollar costs, specific accident scenarios, project funding and changes in Congressional mandates, and project management (contracts, labor relations, quality assurance, liability, emergency preparedness, etc.). These issues will be covered in other documents supporting the decision-making process. Although the scope of this document covers property-cleanup and interim-storage actions, it is applicable to other similar remedial actions. For example, the analyses discussed herein for cleanup activities are applicable to any FUSRAP action that includes site cleanup

  8. Allowable peak heat-up cladding temperature for spent fuel integrity during interim-dry storage

    Directory of Open Access Journals (Sweden)

    Ki-Nam Jang

    2017-12-01

    Full Text Available To investigate allowable peak cladding temperature and hoop stress for maintenance of cladding integrity during interim-dry storage and subsequent transport, zirconium alloy cladding tubes were hydrogen-charged to generate 250 ppm and 500 ppm hydrogen contents, simulating spent nuclear fuel degradation. The hydrogen-charged specimens were heated to four peak temperatures of 250°C, 300°C, 350°C, and 400°C, and then cooled to room temperature at cooling rates of 0.3 °C/min under three tensile hoop stresses of 80 MPa, 100 MPa, and 120 MPa. The cool-down specimens showed that high peak heat-up temperature led to lower hydrogen content and that larger tensile hoop stress generated larger radial hydride fraction and consequently lower plastic elongation. Based on these out-of-pile cladding tube test results only, it may be said that peak cladding temperature should be limited to a level < 250°C, regardless of the cladding hoop stress, to ensure cladding integrity during interim-dry storage and subsequent transport.

  9. Interim analysis of validity of periodontitis screening questions in the Australian population.

    Science.gov (United States)

    Slade, Gary D

    2007-07-01

    The purpose of this study was to provide interim results regarding the validity of six periodontal screening questions in predicting the prevalence of clinically assessed periodontitis among Australian adults. The Australian National Survey of Adult Oral Health is a cross-sectional survey of Australians aged 15 years or older. Subjects were selected using a multistage probability sampling design. The interview included six questions to screen for periodontal disease and five demographic/health history questions that represented traditional risk indicators for the disease. Oral examinations were conducted by trained, calibrated dentists who measured periodontal recession and probing depth at mesio-buccal, mid-buccal, and disto-buccal sites on all erupted teeth. A computer algorithm determined three categories of periodontal case status: none/mild, moderate, or severe. Multivariable binary logistic regression models were constructed using six screening questions, five traditional risk indicators, and all 11 variables. This interim analysis used data from 2,999 subjects who resided in the first five states/territories that completed the survey. Based on clinical findings, 4.0% of subjects were classified with "severe" periodontitis and 25.2% were classified with "moderate" periodontitis. Five screening questions had non-response rates of validity in predicting the prevalence of periodontitis.

  10. Re-use of pilot data and interim analysis of pivotal data in MRMC studies: a simulation study

    Science.gov (United States)

    Chen, Weijie; Samuelson, Frank; Sahiner, Berkman; Petrick, Nicholas

    2017-03-01

    Novel medical imaging devices are often evaluated with multi-reader multi-case (MRMC) studies in which radiologists read images of patient cases for a specified clinical task (e.g., cancer detection). A pilot study is often used to measure the effect size and variance parameters that are necessary for sizing a pivotal study (including sizing readers, non-diseased and diseased cases). Due to the practical difficulty of collecting patient cases or recruiting clinical readers, some investigators attempt to include the pilot data as part of their pivotal study. In other situations, some investigators attempt to perform an interim analysis of their pivotal study data based upon which the sample sizes may be re-estimated. Re-use of the pilot data or interim analyses of the pivotal data may inflate the type I error of the pivotal study. In this work, we use the Roe and Metz model to simulate MRMC data under the null hypothesis (i.e., two devices have equal diagnostic performance) and investigate the type I error rate for several practical designs involving re-use of pilot data or interim analysis of pivotal data. Our preliminary simulation results indicate that, under the simulation conditions we investigated, the inflation of type I error is none or only marginal for some design strategies (e.g., re-use of patient data without re-using readers, and size re-estimation without using the effect-size estimated in the interim analysis). Upon further verifications, these are potentially useful design methods in that they may help make a study less burdensome and have a better chance to succeed without substantial loss of the statistical rigor.

  11. Effect of liquid polishing materials on the stainability of bis-acryl interim restorative material in vitro.

    Science.gov (United States)

    Cakan, Umut; Kara, Haluk Baris

    2015-05-01

    The discoloration of interim restorations may negatively affect a patient's perception of treatment. The purpose of this study was to investigate the effect of liquid polishing materials on the color stability of bis-acryl interim restorative material. One hundred twenty specimens (10×2 mm) of a bis-acryl interim restorative material were divided into 3 groups. Group CO (control) was not subjected to any liquid polishing material. Groups GC and BC were polished with 2 liquid polishing materials. The specimens were then divided into 4 subgroups (n=10) and stored for 24 hours at 37°C in different staining solutions: coffee, coffee with sugar, cola, and distilled water. The color of the specimens was measured at baseline and after immersion with a spectrophotometer by using the CIE L*a*b* system, and color changes (ΔE) were calculated. The means of color change for each specimen were analyzed by 2-way and 1-way ANOVA tests. Post hoc comparisons were made with the Tukey HSD and Tamhane T2 tests. The application of liquid polishing materials significantly decreased the staining of autopolymerized bis-acryl interim restorative material (PCoffee with sugar resulted in higher ΔE values than coffee without sugar or cola. The use of liquid polishing materials significantly decreased staining when compared with bis-acryl specimens without liquid polish. The presence of sugar in coffee increased color change compared with coffee without sugar for all groups evaluated. Copyright © 2015 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

  12. The Safety Assessment of Long term Interim Storage at Sellafield

    International Nuclear Information System (INIS)

    Buchan, Andrew B.

    2014-01-01

    The Sellafield site comprises a wide range of nuclear facilities, including operating facilities associated with the Magnox reprocessing programme, the Thermal Oxide Reprocessing Plant (THORP) and a range of waste treatment plants. The operational life of some of the site facilities currently extends to 2120, requiring the retrieval, treatment, consolidation and safe extended storage of a variety of radioactive materials. Sellafield has utilised its existing safety assessment processes to inform and prioritise studies into beyond design basis events and resilience evaluation required following Fukushima by UK regulators and industry bodies such as WANO. There are significant differences between NPPs, for which the ENSREG 'stress tests' were originally intended, and the Sellafield site which is instead centered around two reprocessing facilities (Magnox and THORP), with a supporting infrastructure of waste processing and storage facilities, coupled with a legacy of high hazard older facilities. In the former case the consequences of a catastrophic failure are promptly realised, leading to significant problems such as fuel failure / meltdown in AGRs and LWRs respectively in the event of complete loss of cooling. At Sellafield, the processes are carried out at comparatively low temperatures and pressures with relatively low rates of change following any loss of cooling. Instead the consequences of catastrophic failure at Sellafield are more directly related to the very large inventories of radioactive materials, including high level liquid wastes and unprocessed fuels, present in specific plants and to the condition of the ageing assets, holding legacy wastes. The paper will consider how a number of analysis techniques have been used to establish a safety case for fault and accident conditions, i.e. design basis analysis (DBA), probabilistic safety analysis (PSA) and severe accident analysis (SAA) DBA is focused on the key safety measures for those initiating faults

  13. Workshop presentations

    International Nuclear Information System (INIS)

    Sanden, Per-Olof; Edland, Anne; Reiersen, Craig; Mullins, Peter; Ingemarsson, Karl-Fredrik; Bouchard, Andre; Watts, Germaine; Johnstone, John; Hollnagel, Erik; Ramberg, Patric; Reiman, Teemu

    2009-01-01

    An important part of the workshop was a series of invited presentations. The presentations were intended to both provide the participants with an understanding of various organisational approaches and activities as well as to stimulate the exchange of ideas during the small group discussion sessions. The presentation subjects ranged from current organisational regulations and licensee activities to new organisational research and the benefits of viewing organisations from a different perspective. There were more than a dozen invited presentations. The initial set of presentations gave the participants an overview of the background, structure, and aims of the workshop. This included a short presentation on the results from the regulatory responses to the pre-workshop survey. Representatives from four countries (Sweden, Canada, Finland, and the United Kingdom) expanded upon their survey responses with detailed presentations on both regulatory and licensee safety-related organisational activities in their countries. There were also presentations on new research concerning how to evaluate safety critical organisations and on a resilience engineering perspective to safety critical organisations. Below is the list of the presentations, the slides of which being available in Appendix 2: 1 - Workshop Welcome (Per-Olof Sanden); 2 - CSNI Working Group on Human and Organisational Factors (Craig Reiersen); 3 - Regulatory expectations on justification of suitability of licensee organisational structures, resources and competencies (Anne Edland); 4 - Justifying the suitability of licensee organisational structures, resources and competencies (Karl-Fredrik Ingemarsson); 5 - Nuclear Organisational Suitability in Canada (Andre Bouchard); 6 - Designing and Resourcing for Safety and Effectiveness (Germaine Watts); 7 - Organisational Suitability - What do you need and how do you know that you've got it? (Craig Reiersen); 8 - Suitability of Organisations - UK Regulator's View

  14. Voting Present

    Directory of Open Access Journals (Sweden)

    James Lo

    2013-12-01

    Full Text Available During his time as a state senator in Illinois, Barack Obama voted “Present” 129 times, a deliberate act of nonvoting that subsequently became an important campaign issue during the 2008 presidential elections. In this article, I examine the use of Present votes in the Illinois state senate. I find evidence that Present votes can largely be characterized as protest votes used as a legislative tool by the minority party. Incorporating information from Present votes into a Bayesian polytomous item-response model, I find that this information increases the efficiency of ideal point estimates by approximately 35%. There is little evidence of significant moderation by Obama when Present votes are accounted for, though my results suggest that Obama’s voting record may have moderated significantly before his subsequent election to the U.S. Senate. My results also suggest that because legislative nonvoting may occur for a variety of reasons, naive inclusion of nonvoting behavior into vote choice models may lead to biased results.

  15. Modified glass ionomer and orthodontic band: An interim alternative for the treatment of molar incisor hypomineralization. A case report.

    Directory of Open Access Journals (Sweden)

    Carla Orellana

    2017-03-01

    Full Text Available Introduction: Molar incisor hypomineralization (MIH is a developmental condition resulting in defects in the enamel characterized by demarcated opacities mainly affecting first permanent molars and occasionally permanent incisors in 1 of every 6 children worldwide. Affected molars have greater susceptibility to post eruptive breakdown, extensive caries and, in severe cases, are difficult to restore. When the MIH-affected molar presents severe crown destruction, it is necessary to perform an intermediate restoration to preserve the remaining dental structure in order to maintain occlusion, proper hygiene and periodontal health. The case of an 11-year-old patient with severe MIH is reported. The patient had extensive crown destruction by caries in tooth 1.6 without clinical or radiographic signs of pulp pathology. After an initial preventive intervention, enamel without dentin support and carious dentin were removed from tooth 1.6. Subsequently, crown restoration was performed with resin-modified glass ionomer, followed by the cementation of an orthodontic band. After 18 months of follow-up, the patient reported no pain or discomfort. The restoration was preserved intact, maintaining occlusal functionality, pulp and gingival health. Conclusion: The interim treatment, cementing an orthodontic band over a tooth restored with glass ionomer seems to favor retention and compressive strength, keeping the MIH-affected molar asymptomatic for at least 18 months. Further studies evaluating this treatment option in similar clinical situations are recommended.

  16. Thermal-hydraulic experiment and analysis for interim dry storage of spent nuclear fuel

    International Nuclear Information System (INIS)

    Yoo, Seung Hun

    2011-02-01

    The experimental and numerical studies of interim storages for nuclear spent fuels have been performed to investigate thermal-hydraulic characteristics of the dry storage systems and to propose new methodologies for the analysis and the design. Three separate researches have been performed in the present study: (a) Development of a scaling methodology and thermal-hydraulic experiment of a single spent fuel assembly simulating a dry storage cask: (b) Full-scope simulation of a dry storage cask by the use of Computational Fluid Dynamics (CFD) code: (c) Thermal-hydraulic design of a tunnel-type interim storage facility. In the first study, a scaling methodology has been developed to design a scaled-down canister. The scaling was performed in two steps. For the first step, the height of a spent fuel assembly was reduced from full height to half height. In order to consider the effect of height reduction on the natural convection, the scaling law of Ishii and Kataoka (1984) was employed. For the second step, the quantity of spent fuel assemblies was reduced from multiple assemblies to a single assembly. The scaling methodology was validated through the comparison with the experiment of the TN24P cask. The Peak Cladding Temperature (PCT), temperature gradients, and the axial and radial temperature distribution in the nondimensional forms were in good agreement with the experimental data. Based on the developed methodology, we have performed a single assembly experiment which was designed to simulate the full scale of the TN24P cask. The experimental data was compared with the CFD calculations. It turns out that their PCTs were less than the maximum allowable temperature for the fuel cladding and that the differences of their PCTs were agreed within 3 .deg. C, which was less than measurement uncertainty. In the second study, the full-scope simulations of the TN24P cask were performed by FLUENT. In order to investigate the sensitivity of the numerical and physical

  17. Interim Report 'Winter smog and traffic'.

    NARCIS (Netherlands)

    Bloemen, H.; Blom, T.; Bogaard, van den C.; Boluyt, N.; Bree, van L.; Brunekreef, B.; Hoek, G.; Zee, van der S.

    1994-01-01

    This report presents a halfway score of the research project "Winter smog and Traffic", one of the themes of the research programme "Air Pollution and Health". A state of the art is presented of the health effects associated with exposure to winter smog and of the toxicological effects caused by the

  18. Mobile Launch Platform Vehicle Assembly Area (SWMU 056) Biosparge Expansion Interim Measures Work Plan

    Science.gov (United States)

    Burcham, Michael S.; Daprato, Rebecca C.

    2016-01-01

    This document presents the design details for an Interim Measure (IM) Work Plan (IMWP) for the Mobile Launch Platform/Vehicle Assembly Building (MLPV) Area, located at the John F. Kennedy Space Center (KSC), Florida. The MLPV Area has been designated Solid Waste Management Unit Number 056 (SWMU 056) under KSC's Resource Conservation and Recovery Act (RCRA) Corrective Action Program. This report was prepared by Geosyntec Consultants (Geosyntec) for the National Aeronautics and Space Administration (NASA) under contract number NNK09CA02B and NNK12CA13B, project control number ENV1642. The Advanced Data Package (ADP) presentation covering the elements of this IMWP report received KSC Remediation Team (KSCRT) approval at the December 2015 Team Meeting; the meeting minutes are included in Appendix A.

  19. FB Line Basis for Interim Operation

    International Nuclear Information System (INIS)

    Shedrow, B.

    1998-01-01

    The safety analysis of the FB-Line Facility indicates that the operation of FB-Line to support the current mission does not present undue risk to the facility and co-located workers, general public, or the environment

  20. FB Line Basis for Interim Operation

    Energy Technology Data Exchange (ETDEWEB)

    Shedrow, B.

    1998-10-19

    The safety analysis of the FB-Line Facility indicates that the operation of FB-Line to support the current mission does not present undue risk to the facility and co-located workers, general public, or the environment.

  1. [Correlation between childhood traumatic stress and present drug abuse: results of a nationwide survey of drug addiction rehabilitation facilities in Japan].

    Science.gov (United States)

    Umeno, Mitsuru; Morita, Nobuaki; Ikeda, Tomohiro; Koda, Minoru; Abe, Yukie; Endo, Keiko; Yabe, Yohko; Hirai, Hideyuki; Takahashi, Koji; Aikawa, Yuzo; Senoo, Eiichi; Nakatani, Yoji

    2009-12-01

    Child abuse is known to correlate with drug abuse and interferes with recovery from substance-related disorders. To determine the prevalence and severity of child abuse among drug addicts, we conducted a nationwide cross-sectional survey of residents and outpatients at drug addiction rehabilitation centers (DARC) in Japan. A total of 445 participants gave informed consent and completed a self-reporting questionnaire. Sixty-eight percent of participants had experienced some kind of child abuse by the time they reached junior high school. The kinds of abuse experienced were physical (53.7%), psychological (60.4%), sexual (5.4%) abuse and neglect (24.5%). Comparison of female and male participants revealed that more female than male participants had experienced psychological (76.9% vs. 58.2%) and sexual (17.5% vs. 4.0%) abuse. Comparison of participants who had experienced some kind of child abuse ("Abused" group 68.3%) and those who had not experienced abuse ("Non-abused" group 24.3%) revealed that the "Abused" group was younger than the "Non-abused" group (35.7 SD9.0 vs. 39.7 SD10.8). Participants in the "Abused" group were found to have more severe psychological difficulties than those in the "Non-abused" group for the following: anxiety (73.0% vs. 61.1%), delusional atmosphere (48.0% vs. 28.7%), lack of energy (53.9% vs. 40.7%), ideas of persecution (48.7% vs. 29.6%), depression (62.2% vs. 43.5%) and suicidal ideation in the previous year (50.7% vs. 24.3%). The present results suggest that additional program that prepared to care the drug addicts who experienced child abuse and are experiencing suicidal ideation is needed. Furthermore, intervention for families with risk factors for child abuse should be developed in order to prevent the victim from suffering not only from post traumatic stress disorder but also from substance related disorders.

  2. Comparative study of marginal adaptation and mechanical properties of CAD/CAM versus dual polymerized interim fixed dental prosthesis

    Directory of Open Access Journals (Sweden)

    Marwa Eltayeb I Elagra

    2014-01-01

    Conclusions: CAD/CAM fabricated interim restorations have better marginal adaptation, wear resistance and fracture resistance than dual polymerized interim restorations hence, might withstand longer duration in the oral cavity.

  3. Environmental survey of two interim dumpsites, Middle Atlantic Bight from 05 November 1973 to 10 November 1973 (NODC Accession 7501280)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — A second oceanographic survey cruise was made to an interim municipal sludge dumpsite and initially to an interim dumpsite for the disposal of industrial acid waste...

  4. Idiopathic infantile arterial calcification in a 12-year-old girl presenting as chronic mesenteric ischemia: imaging findings and angioplasty results

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Edwin; Owen, Richard [University of Alberta, Department of Radiology and Diagnostic Imaging, Edmonton (Canada); Bruce, Garth [University of Saskatchewan, Department of Pediatrics, Royal University Hospital, Saskatoon (Canada); Wiebe, Sheldon [University of Saskatchewan, Department of Medical Imaging, Royal University Hospital, Saskatoon (Canada)

    2011-11-15

    We report an unusual case of chronic mesenteric ischemia presenting in a 12-year-old girl with idiopathic infantile arterial calcinosis (IIAC). This is the first reported case in the literature of chronic mesenteric ischemia in the setting of IIAC. The girl presented with a classical history of postprandial abdominal pain. Imaging demonstrated significant stenoses of the celiac axis, superior mesenteric artery (SMA) and inferior mesenteric artery (IMA). Angioplasty of the celiac axis and SMA was attempted, with successful dilation of the SMA only. At 3-, 6- and 12-month follow-ups, the child's symptoms had almost resolved. This case report has three important ramifications: chronic mesenteric ischemia is a possible clinical presentation in children with IACC, pre-angioplasty imaging is important in guiding treatment approach, and angioplasty was effective in this case of chronic mesenteric ischemia and offers hope for other similarly affected children. (orig.)

  5. Frequency and correlates of late presentation for HIV infection in France: older adults are a risk group - results from the ANRS-VESPA2 Study, France.

    Science.gov (United States)

    Wilson, Kayigan d'Almeida; Dray-Spira, Rosemary; Aubrière, Cindy; Hamelin, Christine; Spire, Bruno; Lert, France

    2014-01-01

    Correlates of late presentation (LP) for HIV infection in Metropolitan France and French overseas departments (FODs) were assessed among HIV-infected patients recently diagnosed, using data from a large cross-sectional survey, representative of the French HIV-infected population, conducted in 2011. LP was defined as presentation with either clinical AIDS events within the calendar year of diagnosis or CD4 France and FODs. In Metropolitan France, 47.7% of participants were late presenters and 29.3% presented with advanced disease. LP was more frequent among male and female migrants from sub-Saharan Africa (SSA; 58.5% and 56.4%) and non-African heterosexual males (61.8%) than among men who have sex with men (34.8%). In FODs, 53.2% of participants were late presenters and 36.8% presented with an advanced disease. LP was more frequent among men than women (60.6% vs. 45.3%) and among those with a lower level of education (56.6% vs. 47.5%). A consistent positive association was found in adjusted analyses between LP/PAD and increasing age at diagnosis among all subpopulations, in both settings. In Metropolitan France, among men who have sex with men, those self-declaring as bisexual were at higher risk of LP/PAD; among non-African heterosexual males and females, religiosity was associated with increased risk of LP/PAD; and among SSA migrants, those diagnosed within the year following their arrival in France were at higher risk of LP/PAD. Older age at diagnosis is a major risk factor for LP/PAD independently of any other socio-demographic characteristics. Promotion of HIV testing should be renewed to target each subgroup at risk while paying a particular attention to middle-aged or older adults whose attitudes and beliefs towards HIV/AIDS might prevent them from seeking testing.

  6. Intrinsic bioremediation of landfills interim report

    International Nuclear Information System (INIS)

    Brigmon, R.L.; Fliermans, C.B.

    1997-01-01

    Intrinsic bioremediation is a risk management option that relies on natural biological and physical processes to contain the spread of contamination from a source. Evidence is presented in this report that intrinsic bioremediation is occurring at the Sanitary Landfill is fundamental to support incorportion into a Corrective Action Plan (CAP)

  7. Intrinsic bioremediation of landfills interim report

    Energy Technology Data Exchange (ETDEWEB)

    Brigmon, R.L. [Westinghouse Savannah River Company, Aiken, SC (United States); Fliermans, C.B.

    1997-07-14

    Intrinsic bioremediation is a risk management option that relies on natural biological and physical processes to contain the spread of contamination from a source. Evidence is presented in this report that intrinsic bioremediation is occurring at the Sanitary Landfill is fundamental to support incorportion into a Corrective Action Plan (CAP).

  8. 42 CFR 93.401 - Interaction with other offices and interim actions.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Interaction with other offices and interim actions. 93.401 Section 93.401 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES... Human Services General Information § 93.401 Interaction with other offices and interim actions. (a) ORI...

  9. 42 CFR 417.572 - Budget and enrollment forecast and interim reports.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Budget and enrollment forecast and interim reports... PLANS, AND HEALTH CARE PREPAYMENT PLANS Medicare Payment: Cost Basis § 417.572 Budget and enrollment forecast and interim reports. (a) Annual submittal. The HMO or CMP must submit an annual operating budget...

  10. Conceptual design report for immobilized high-level waste interim storage facility (Phase 1)

    Energy Technology Data Exchange (ETDEWEB)

    Burgard, K.C.

    1998-04-09

    The Hanford Site Canister Storage Building (CSB Bldg. 212H) will be utilized to interim store Phase 1 HLW products. Project W-464, Immobilized High-Level Waste Interim Storage, will procure an onsite transportation system and retrofit the CSB to accommodate the Phase 1 HLW products. The Conceptual Design Report establishes the Project W-464 technical and cost basis.

  11. EPA Interim Evaluation of 2016-2017 Milestone Progress in the Chesapeake Bay Watershed

    Science.gov (United States)

    This page provides the EPA interim evaluations of the 2016-2017 milestones for the Chesapeake Bay TMDL. These interim assessments provide a mid-point check on the progress made on the 2016-2017 milestones, recognizing the achievements made in 2016.

  12. EPA Interim Evaluation of 2012-2013 Milestone Progress in the Chesapeake Bay Watershed

    Science.gov (United States)

    This page provides the EPA interim evaluations of the 2012-2013 milestones for the Chesapeake Bay TMDL. These interim assessments provide a mid-point check on the progress made on the 2012-2013 milestones, recognizing the achievements made in 2012.

  13. EPA Interim Evaluation of 2014-2015 Milestone Progress in the Chesapeake Bay Watershed

    Science.gov (United States)

    This page provides the EPA interim evaluations of the 2014-2015 milestones for the Chesapeake Bay TMDL. These interim assessments provide a mid-point check on the progress made on the 2014-2015 milestones, recognizing the achievements made in 2014.

  14. 40 CFR 80.156 - Liability for violations of the interim detergent program controls and prohibitions.

    Science.gov (United States)

    2010-07-01

    ... interim detergent program controls and prohibitions. 80.156 Section 80.156 Protection of Environment... Detergent Gasoline § 80.156 Liability for violations of the interim detergent program controls and..., carrier, distributor, reseller, retailer, wholesale purchaser-consumer, oxygenate blender, or detergent...

  15. 40 CFR 80.155 - Interim detergent program controls and prohibitions.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false Interim detergent program controls and... PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Detergent Gasoline § 80.155 Interim detergent... wholesale purchaser-consumer, and no person shall detergent-additize gasoline, unless such gasoline is...

  16. Conceptual design report for immobilized high-level waste interim storage facility (Phase 1)

    Energy Technology Data Exchange (ETDEWEB)

    Burgard, K.C.

    1998-06-02

    The Hanford Site Canister Storage Building (CSB Bldg. 212H) will be utilized to interim store Phase 1 HLW products. Project W-464, Immobilized High-Level Waste Interim Storage, will procure an onsite transportation system and retrofit the CSB to accommodate the Phase 1 HLW products. The Conceptual Design Report establishes the Project W-464 technical and cost basis.

  17. 32 CFR 643.36 - Policy-Interim leasing of excess properties to facilitate economic readjustment.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Policy-Interim leasing of excess properties to facilitate economic readjustment. 643.36 Section 643.36 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) REAL PROPERTY REAL ESTATE Policy § 643.36 Policy—Interim leasing of excess...

  18. Interim format and content for a physical security plan for nuclear power plants

    International Nuclear Information System (INIS)

    1977-02-01

    The document serves as interim guidance to assist the licensee or applicant in the preparation of a physical security plan. It is to be used in conjunction with interim acceptance criteria for physical security programs, which will be distributed at a later date

  19. 30 CFR 827.13 - Coal preparation plants: Interim performance standards.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Coal preparation plants: Interim performance...-COAL PREPARATION PLANTS NOT LOCATED WITHIN THE PERMIT AREA OF A MINE § 827.13 Coal preparation plants: Interim performance standards. (a) Persons operating or who have operated coal preparation plants after...

  20. WRF high resolution dynamical downscaling of ERA-Interim for Portugal

    Energy Technology Data Exchange (ETDEWEB)

    Soares, Pedro M.M. [University of Lisbon, Instituto Dom Luiz, Lisbon (Portugal); Faculdade de Ciencias da Universidade de Lisboa, Lisbon (Portugal); Cardoso, Rita M.; Miranda, Pedro M.A.; Medeiros, Joana de [University of Lisbon, Instituto Dom Luiz, Lisbon (Portugal); Belo-Pereira, Margarida; Espirito-Santo, Fatima [Instituto de Meteorologia, Lisbon (Portugal)

    2012-11-15

    This study proposes a dynamically downscaled climatology of Portugal, produced by a high resolution (9 km) WRF simulation, forced by 20 years of ERA-Interim reanalysis (1989-2008), nested in an intermediate domain with 27 km of resolution. The Portuguese mainland is characterized by large precipitation gradients, with observed mean annual precipitation ranging from about 400 to over 2,200 mm, with a very wet northwest and rather dry southeast, largely explained by orographic processes. Model results are compared with all available stations with continuous records, comprising daily information in 32 stations for temperature and 308 for precipitation, through the computation of mean climatologies, standard statistical errors on daily to seasonally timescales, and distributions of extreme events. Results show that WRF at 9 km outperforms ERA-Interim in all analyzed variables, with good results in the representation of the annual cycles in each region. The biases of minimum and maximum temperature are reduced, with improvement of the description of temperature variability at the extreme range of its distribution. The largest gain of the high resolution simulations is visible in the rainiest regions of Portugal, where orographic enhancement is crucial. These improvements are striking in the high ranking percentiles in all seasons, describing extreme precipitation events. WRF results at 9 km compare favorably with published results supporting its use as a high-resolution regional climate model. This higher resolution allows a better representation of extreme events that are of major importance to develop mitigation/adaptation strategies by policy makers and downstream users of regional climate models in applications such as flash floods or heat waves. (orig.)