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Sample records for intel gma x3100

  1. Intel Galileo essentials

    CERN Document Server

    Grimmett, Richard

    2015-01-01

    This book is for anyone who has ever been curious about using the Intel Galileo to create electronics projects. Some programming background is useful, but if you know how to use a personal computer, with the aid of the step-by-step instructions in this book, you can construct complex electronics projects that use the Intel Galileo.

  2. Home automation with Intel Galileo

    CERN Document Server

    Dundar, Onur

    2015-01-01

    This book is for anyone who wants to learn Intel Galileo for home automation and cross-platform software development. No knowledge of programming with Intel Galileo is assumed, but knowledge of the C programming language is essential.

  3. Intel: High Throughput Computing Collaboration: A CERN openlab / Intel collaboration

    CERN Multimedia

    CERN. Geneva

    2015-01-01

    The Intel/CERN High Throughput Computing Collaboration studies the application of upcoming Intel technologies to the very challenging environment of the LHC trigger and data-acquisition systems. These systems will need to transport and process many terabits of data every second, in some cases with tight latency constraints. Parallelisation and tight integration of accelerators and classical CPU via Intel's OmniPath fabric are the key elements in this project.

  4. Windows for Intel Macs

    CERN Document Server

    Ogasawara, Todd

    2008-01-01

    Even the most devoted Mac OS X user may need to use Windows XP, or may just be curious about XP and its applications. This Short Cut is a concise guide for OS X users who need to quickly get comfortable and become productive with Windows XP basics on their Macs. It covers: Security Networking ApplicationsMac users can easily install and use Windows thanks to Boot Camp and Parallels Desktop for Mac. Boot Camp lets an Intel-based Mac install and boot Windows XP on its own hard drive partition. Parallels Desktop for Mac uses virtualization technology to run Windows XP (or other operating systems

  5. INTEL: Intel based systems move up in supercomputing ranks

    CERN Multimedia

    2002-01-01

    "The TOP500 supercomputer rankings released today at the Supercomputing 2002 conference show a dramatic increase in the number of Intel-based systems being deployed in high-performance computing (HPC) or supercomputing areas" (1/2 page).

  6. GMA200 ATEGG Digital Controls Demonstration.

    Science.gov (United States)

    1979-10-01

    radial and axial loads into the air inlet housing and forward frame. c. Combustor/Diffuser The GMA200 combustor/diffuser section consists of an annular...transition flow path of a turbofan engine. 6 IT U’~ --sa b. Compressor A six-stage axial flow compressor assembly consists of subassemblies of the...savings in the highly loaded , high speed unit. The blade is cooled by the application of a variety of cooling techniques including a film-cooled leading

  7. Accessing Intel FPGAs for Acceleration

    CERN Multimedia

    CERN. Geneva

    2018-01-01

    In this presentation, we will discuss the latest tools and products from Intel that enables FPGAs to be deployed as Accelerators. We will first talk about the Acceleration Stack for Intel Xeon CPU with FPGAs which makes it easy to create, verify, and execute functions on the Intel Programmable Acceleration Card in a Data Center. We will then talk about the OpenCL flow which allows parallel software developers to create FPGA systems and deploy them using the OpenCL standard. Next, we will talk about the Intel High-Level Synthesis compiler which can convert C++ code into custom RTL code optimized for Intel FPGAs. Lastly, we will focus on the task of running Machine Learning inference on the FPGA leveraging some of the tools we discussed. About the speaker Karl Qi is Sr. Staff Applications Engineer, Technical Training. He has been with the Customer Training department at Altera/Intel for 8 years. Most recently, he is responsible for all training content relating to High-Level Design tools, including the OpenCL...

  8. Stabilitas emulsi kopolimer S-GMA (stirena – glisidil metakrilat

    Directory of Open Access Journals (Sweden)

    Isananto Winursito

    1992-08-01

    Full Text Available Epoxy groups in glycidyl methacrylate (GMA units have been available for the reaction with amine of proteins or other biological active substrates to prepare biomaterials and hybrid devices. Soap-soap copolymerization of GMA with styrene (S result the formation of stable latex. Hydrolysis of epoxy groups in copolymer particles increased emulsion stability. The effect of pH, temperature and reaction time in the hydrolysis of S-GMA copolymer have been investigated.

  9. Intel Xeon Phi coprocessor high performance programming

    CERN Document Server

    Jeffers, James

    2013-01-01

    Authors Jim Jeffers and James Reinders spent two years helping educate customers about the prototype and pre-production hardware before Intel introduced the first Intel Xeon Phi coprocessor. They have distilled their own experiences coupled with insights from many expert customers, Intel Field Engineers, Application Engineers and Technical Consulting Engineers, to create this authoritative first book on the essentials of programming for this new architecture and these new products. This book is useful even before you ever touch a system with an Intel Xeon Phi coprocessor. To ensure that your applications run at maximum efficiency, the authors emphasize key techniques for programming any modern parallel computing system whether based on Intel Xeon processors, Intel Xeon Phi coprocessors, or other high performance microprocessors. Applying these techniques will generally increase your program performance on any system, and better prepare you for Intel Xeon Phi coprocessors and the Intel MIC architecture. It off...

  10. New compilers speed up applications for Intel-based systems; Intel Compilers pave the way for Intel's Hyper-threading technology

    CERN Multimedia

    2002-01-01

    "Intel Corporation today introduced updated tools to help software developers optimize applications for Intel's expanding family of architectures with key innovations such as Intel's Hyper Threading Technology (1 page).

  11. Scientific Computing and Apple's Intel Transition

    CERN Document Server

    CERN. Geneva

    2006-01-01

    Intel's published processor roadmap and how it may affect the future of personal and scientific computing About the speaker: Eric Albert is Senior Software Engineer in Apple's Core Technologies group. During Mac OS X's transition to Intel processors he has worked on almost every part of the operating system, from the OS kernel and compiler tools to appli...

  12. Unlock performance secrets of next-gen Intel hardware

    CERN Multimedia

    CERN. Geneva

    2015-01-01

    Intel® Xeon Phi Product. About the speaker Zakhar is a software architect in Intel SSG group. His current role is Parallel Studio architect with focus on SIMD vector parallelism assistance tools. Before it he was working as Intel Advisor XE software architect and software development team-lead. Before joining Intel he was...

  13. Intel Corporation osaleb Eesti koolitusprogrammis / Raivo Juurak

    Index Scriptorium Estoniae

    Juurak, Raivo, 1949-

    2001-01-01

    Haridusministeeriumis tutvustati infotehnoloogiaalast koolitusprogrammi, milles osaleb maailma suuremaid arvutifirmasid Intel Corporation. Koolituskursuse käigus õpetatakse aineõpetajaid oma ainetundides interneti võimalusi kasutama. 50-tunnised kursused viiakse läbi kõigis maakondades

  14. Structure and properties of GMA surfaced armour plates

    OpenAIRE

    A. Klimpel; K. Luksa; M. Burda

    2010-01-01

    Purpose: In the combat vehicles many materials can be used for the armour. Application of the monolithic armour plates in light combat vehicles is limited by the high armour weigh. Introduction of the layered armour plates is a way to limit the vehicle weight. In the paper test results of graded and nanostructural GMA surfaced armour plates are presented.Design/methodology/approach: Metallographic structure, chemical composition and hardness of surfaced layers were investigated in order to ex...

  15. Effective SIMD Vectorization for Intel Xeon Phi Coprocessors

    OpenAIRE

    Tian, Xinmin; Saito, Hideki; Preis, Serguei V.; Garcia, Eric N.; Kozhukhov, Sergey S.; Masten, Matt; Cherkasov, Aleksei G.; Panchenko, Nikolay

    2015-01-01

    Efficiently exploiting SIMD vector units is one of the most important aspects in achieving high performance of the application code running on Intel Xeon Phi coprocessors. In this paper, we present several effective SIMD vectorization techniques such as less-than-full-vector loop vectorization, Intel MIC specific alignment optimization, and small matrix transpose/multiplication 2D vectorization implemented in the Intel C/C++ and Fortran production compilers for Intel Xeon Phi coprocessors. A ...

  16. Hydrogels based on chemically modified poly(vinyl alcohol (PVA-GMA and PVA-GMA/chondroitin sulfate: Preparation and characterization

    Directory of Open Access Journals (Sweden)

    E. C. Muniz

    2012-05-01

    Full Text Available This work reports the preparation of hydrogels based on PVA-GMA, PVA-GMA is poly(vinyl alcohol (PVA functionalized with vinyl groups from glycidyl methacrylate (GMA, and on PVA-GMA with different content of chondroitin sulfate (CS. The degrees of swelling of PVA-GMA and PVA-GMA/CS hydrogels were evaluated in distilled water and the swelling kinetics was performed in simulated gastric and intestinal fluids (SGF and SIF. PVA-GMA and PVAGMA/CS hydrogels demonstrated to be resistant on SGF and SIF fluids. The elastic modulus, E, of swollen-hydrogels were determined through compressive tests and, according to the obtained results, the hydrogels presented good mechanical properties. At last, the presence of CS enhances the hydrogel cell compatibility as gathered by cytotoxicity assays. It was concluded that the hydrogels prepared through this work presented characteristics that allow them to be used as biomaterial, as a carrier in drug delivery system or to act as scaffolds in tissue engineering as well.

  17. Theorem Proving in Intel Hardware Design

    Science.gov (United States)

    O'Leary, John

    2009-01-01

    For the past decade, a framework combining model checking (symbolic trajectory evaluation) and higher-order logic theorem proving has been in production use at Intel. Our tools and methodology have been used to formally verify execution cluster functionality (including floating-point operations) for a number of Intel products, including the Pentium(Registered TradeMark)4 and Core(TradeMark)i7 processors. Hardware verification in 2009 is much more challenging than it was in 1999 - today s CPU chip designs contain many processor cores and significant firmware content. This talk will attempt to distill the lessons learned over the past ten years, discuss how they apply to today s problems, outline some future directions.

  18. CERN welcomes Intel Science Fair winners

    CERN Multimedia

    Katarina Anthony

    2012-01-01

    This June, CERN welcomed twelve gifted young scientists aged 15-18 for a week-long visit of the Laboratory. These talented students were the winners of a special award co-funded by CERN and Intel, given yearly at the Intel International Science and Engineering Fair (ISEF).   The CERN award winners at the Intel ISEF 2012 Special Awards Ceremony. © Society for Science & the Public (SSP). The CERN award was set up back in 2009 as an opportunity to bring some of the best and brightest young minds to the Laboratory. The award winners are selected from among 1,500 talented students participating in ISEF – the world's largest pre-university science competition, in which students compete for more than €3 million in awards. “CERN gave an award – which was obviously this trip – to students studying physics, maths, electrical engineering and computer science,” says Benjamin Craig Bartlett, 17, from South Carolina, USA, wh...

  19. Experience with Intel's Many Integrated Core Architecture in ATLAS Software

    CERN Document Server

    Fleischmann, S; The ATLAS collaboration; Lavrijsen, W; Neumann, M; Vitillo, R

    2014-01-01

    Intel recently released the first commercial boards of its Many Integrated Core (MIC) Architecture. MIC is Intel's solution for the domain of throughput computing, currently dominated by general purpose programming on graphics processors (GPGPU). MIC allows the use of the more familiar x86 programming model and supports standard technologies such as OpenMP, MPI, and Intel's Threading Building Blocks. This should make it possible to develop for both throughput and latency devices using a single code base.\

  20. Experience with Intel's Many Integrated Core Architecture in ATLAS Software

    CERN Document Server

    Fleischmann, S; The ATLAS collaboration; Lavrijsen, W; Neumann, M; Vitillo, R

    2013-01-01

    Intel recently released the first commercial boards of its Many Integrated Core (MIC) Architecture. MIC is Intel's solution for the domain of throughput computing, currently dominated by general purpose programming on graphics processors (GPGPU). MIC allows the use of the more familiar x86 programming model and supports standard technologies such as OpenMP, MPI, and Intel's Threading Building Blocks. This should make it possible to develop for both throughput and latency devices using a single code base.\

  1. Parallel Programming with Intel Parallel Studio XE

    CERN Document Server

    Blair-Chappell , Stephen

    2012-01-01

    Optimize code for multi-core processors with Intel's Parallel Studio Parallel programming is rapidly becoming a "must-know" skill for developers. Yet, where to start? This teach-yourself tutorial is an ideal starting point for developers who already know Windows C and C++ and are eager to add parallelism to their code. With a focus on applying tools, techniques, and language extensions to implement parallelism, this essential resource teaches you how to write programs for multicore and leverage the power of multicore in your programs. Sharing hands-on case studies and real-world examples, the

  2. Trusted Computing Technologies, Intel Trusted Execution Technology.

    Energy Technology Data Exchange (ETDEWEB)

    Guise, Max Joseph; Wendt, Jeremy Daniel

    2011-01-01

    We describe the current state-of-the-art in Trusted Computing Technologies - focusing mainly on Intel's Trusted Execution Technology (TXT). This document is based on existing documentation and tests of two existing TXT-based systems: Intel's Trusted Boot and Invisible Things Lab's Qubes OS. We describe what features are lacking in current implementations, describe what a mature system could provide, and present a list of developments to watch. Critical systems perform operation-critical computations on high importance data. In such systems, the inputs, computation steps, and outputs may be highly sensitive. Sensitive components must be protected from both unauthorized release, and unauthorized alteration: Unauthorized users should not access the sensitive input and sensitive output data, nor be able to alter them; the computation contains intermediate data with the same requirements, and executes algorithms that the unauthorized should not be able to know or alter. Due to various system requirements, such critical systems are frequently built from commercial hardware, employ commercial software, and require network access. These hardware, software, and network system components increase the risk that sensitive input data, computation, and output data may be compromised.

  3. Radiation Failures in Intel 14nm Microprocessors

    Science.gov (United States)

    Bossev, Dobrin P.; Duncan, Adam R.; Gadlage, Matthew J.; Roach, Austin H.; Kay, Matthew J.; Szabo, Carl; Berger, Tammy J.; York, Darin A.; Williams, Aaron; LaBel, K.; hide

    2016-01-01

    In this study the 14 nm Intel Broadwell 5th generation core series 5005U-i3 and 5200U-i5 was mounted on Dell Inspiron laptops, MSI Cubi and Gigabyte Brix barebones and tested with Windows 8 and CentOS7 at idle. Heavy-ion-induced hard- and catastrophic failures do not appear to be related to the Intel 14nm Tri-Gate FinFET process. They originate from a small (9 m 140 m) area on the 32nm planar PCH die (not the CPU) as initially speculated. The hard failures seem to be due to a SEE but the exact physical mechanism has yet to be identified. Some possibilities include latch-ups, charge ion trapping or implantation, ion channels, or a combination of those (in biased conditions). The mechanism of the catastrophic failures seems related to the presence of electric power (1.05V core voltage). The 1064 nm laser mimics ionization radiation and induces soft- and hard failures as a direct result of electron-hole pair production, not heat. The 14nm FinFET processes continue to look promising for space radiation environments.

  4. An INTEL 8080 microprocessor development system

    International Nuclear Information System (INIS)

    Horne, P.J.

    1977-01-01

    The INTEL 8080 has become one of the two most widely used microprocessors at CERN, the other being the MOTOROLA 6800. Even thouth this is the case, there have been, to date, only rudimentary facilities available for aiding the development of application programs for this microprocessor. An ideal development system is one which has a sophisticated editing and filing system, an assembler/compiler, and access to the microprocessor application. In many instances access to a PROM programmer is also required, as the application may utilize only PROMs for program storage. With these thoughts in mind, an INTEL 8080 microprocessor development system was implemented in the Proton Synchrotron (PS) Division. This system utilizes a PDP 11/45 as the editing and file-handling machine, and an MSC 8/MOD 80 microcomputer for assembling, PROM programming and debugging user programs at run time. The two machines are linked by an existing CAMAC crate system which will also provide the means of access to microprocessor applications in CAMAC and the interface of the development system to any other application. (Auth.)

  5. Effective SIMD Vectorization for Intel Xeon Phi Coprocessors

    Directory of Open Access Journals (Sweden)

    Xinmin Tian

    2015-01-01

    Full Text Available Efficiently exploiting SIMD vector units is one of the most important aspects in achieving high performance of the application code running on Intel Xeon Phi coprocessors. In this paper, we present several effective SIMD vectorization techniques such as less-than-full-vector loop vectorization, Intel MIC specific alignment optimization, and small matrix transpose/multiplication 2D vectorization implemented in the Intel C/C++ and Fortran production compilers for Intel Xeon Phi coprocessors. A set of workloads from several application domains is employed to conduct the performance study of our SIMD vectorization techniques. The performance results show that we achieved up to 12.5x performance gain on the Intel Xeon Phi coprocessor. We also demonstrate a 2000x performance speedup from the seamless integration of SIMD vectorization and parallelization.

  6. Temperature Histories of Structural Steel Laser and Hybrid Laser-GMA Welds Calculated Using Multiple Constraints

    Science.gov (United States)

    2015-12-10

    Laboratory (Ret.), private communication. 33. S. Kou, Welding Metallurgy , 2nd Ed., John Wiley & Sons, Inc., 2003. DOI: 10.1002/0471434027. 34. J. K...Naval Research Laboratory Washington, DC 20375-5320 NRL/MR/6390--15-9665 Temperature Histories of Structural Steel Laser and Hybrid Laser-GMA Welds ...NUMBER OF PAGES 17. LIMITATION OF ABSTRACT Temperature Histories of Structural Steel Laser and Hybrid Laser-GMA Welds Calculated Using Multiple

  7. Grafting of GMA and some comonomers onto chitosan for controlled release of diclofenac sodium.

    Science.gov (United States)

    Sharma, Rajeev Kr; Lalita; Singh, Anirudh P; Chauhan, Ghanshyam S

    2014-03-01

    In order to develop pH sensitive hydrogels for controlled drug release we have graft copolymerized glycidyl methacrylate (GMA) with comonomers acrylic acid, acrylamide and acrylonitrile, onto chitosan (Ch) by using potassium persulphate (KPS) as free radical initiator in aqueous solution. The optimum percent grafting for GMA was recorded for 1g chitosan at [KPS]=25.00 × 10(-3)mol/L, [GMA]=0.756 × 10(-3)mol/L, reaction temperature=60 °C and reaction time=1h in 20 mL H2O. Binary monomers were grafted for five different concentrations at optimum grafting conditions evaluated for GMA alone onto chitosan. The graft copolymers were characterized by FTIR, XRD, TGA and SEM. The swelling properties of chitosan and graft copolymers were investigated at different pH to define their end uses in sustained release of an anti-inflammatory drug, diclofenac sodium. Percent drug release w.r.t. drug loaded in polymeric sample was studied as function of time in buffer solutions of pH 2.0 and 7.4. In vitro release data was analyzed using Fick's Law. Chitosan grafted with binary monomers, GMA-co-AAm and GMA-co-AN showed very good results for sustained release of drug at 7.4 pH. Copyright © 2014 Elsevier B.V. All rights reserved.

  8. Analysis of Intel IA-64 Processor Support for Secure Systems

    National Research Council Canada - National Science Library

    Unalmis, Bugra

    2001-01-01

    .... Systems could be constructed for which serious security threats would be eliminated. This thesis explores the Intel IA-64 processor's hardware support and its relationship to software for building a secure system...

  9. MILC staggered conjugate gradient performance on Intel KNL

    OpenAIRE

    DeTar, Carleton; Doerfler, Douglas; Gottlieb, Steven; Jha, Ashish; Kalamkar, Dhiraj; Li, Ruizi; Toussaint, Doug

    2016-01-01

    We review our work done to optimize the staggered conjugate gradient (CG) algorithm in the MILC code for use with the Intel Knights Landing (KNL) architecture. KNL is the second gener- ation Intel Xeon Phi processor. It is capable of massive thread parallelism, data parallelism, and high on-board memory bandwidth and is being adopted in supercomputing centers for scientific research. The CG solver consumes the majority of time in production running, so we have spent most of our effort on it. ...

  10. [Intel random number generator-based true random number generator].

    Science.gov (United States)

    Huang, Feng; Shen, Hong

    2004-09-01

    To establish a true random number generator on the basis of certain Intel chips. The random numbers were acquired by programming using Microsoft Visual C++ 6.0 via register reading from the random number generator (RNG) unit of an Intel 815 chipset-based computer with Intel Security Driver (ISD). We tested the generator with 500 random numbers in NIST FIPS 140-1 and X(2) R-Squared test, and the result showed that the random number it generated satisfied the demand of independence and uniform distribution. We also compared the random numbers generated by Intel RNG-based true random number generator and those from the random number table statistically, by using the same amount of 7500 random numbers in the same value domain, which showed that the SD, SE and CV of Intel RNG-based random number generator were less than those of the random number table. The result of u test of two CVs revealed no significant difference between the two methods. Intel RNG-based random number generator can produce high-quality random numbers with good independence and uniform distribution, and solves some problems with random number table in acquisition of the random numbers.

  11. Building a robust distributed system: some lessons from R-GMA

    International Nuclear Information System (INIS)

    Bhatti, P; Duncan, A; Fisher, S M; Jiang, M; Kuseju, A O; Paventhan, A; Wilson, A J

    2008-01-01

    R-GMA, as deployed by LCG, is a large distributed system. We are currently addressing some design issues to make it highly reliable, and fault tolerant. In validating the new design, there were two classes of problems to consider: one related to the flow of data and the other to the loss of control messages. R-GMA streams data from one place to another; there is a need to consider the behaviour when data is being inserted more rapidly into the system than taken out and more generally how to deal with bottlenecks. In the original R-GMA design the system tried hard to deliver all control messages; those messages that were not delivered quickly were queued for retry later. Badly configured firewalls, network problems or very slow machines could all lead to long queues of messages; many of the messages on the queue should have been replaced by later ones. In the new design no individual control message is critical; the system just needs to know if each message was received successfully. The system should also avoid single points of failure. However this can require complex code resulting in a system that is actually less reliable. We describe how we have dealt with bottlenecks in the flow of data, loss of control messages and the elimination of single points of failure to produce a robust R-GMA design. The work presented, though in the context of R-GMA, is applicable to any large distributed system

  12. Performance of Artificial Intelligence Workloads on the Intel Core 2 Duo Series Desktop Processors

    OpenAIRE

    Abdul Kareem PARCHUR; Kuppangari Krishna RAO; Fazal NOORBASHA; Ram Asaray SINGH

    2010-01-01

    As the processor architecture becomes more advanced, Intel introduced its Intel Core 2 Duo series processors. Performance impact on Intel Core 2 Duo processors are analyzed using SPEC CPU INT 2006 performance numbers. This paper studied the behavior of Artificial Intelligence (AI) benchmarks on Intel Core 2 Duo series processors. Moreover, we estimated the task completion time (TCT) @1 GHz, @2 GHz and @3 GHz Intel Core 2 Duo series processors frequency. Our results show the performance scalab...

  13. Comparative VME Performance Tests for MEN A20 Intel-L865 and RIO-3 PPC-LynxOS platforms

    CERN Document Server

    Andersen, M; CERN. Geneva. BE Department

    2009-01-01

    This benchmark note presents test results from reading values over VME using different methods and different sizes of data registers, running on two different platforms Intel-L865 and PPC-LynxOS. We find that the PowerPC is a factor 3 faster in accessing an array of contiguous VME memory locations. Block transfer and DMA read accesses are also tested and compared with conventional single access reads.

  14. Effect of glycidyl methacrylate (GMA) incorporation on water uptake and conductivity of proton exchange membranes

    Science.gov (United States)

    Sproll, Véronique; Schmidt, Thomas J.; Gubler, Lorenz

    2018-03-01

    The aim of this work was to investigate how hygroscopic moieties like hydrolyzed glycidyl methacrylate (GMA) influence the properties of sulfonated polysytrene based proton exchange membranes (PEM). Therefore, several membranes were synthesized by electron beam treatment of the ETFE (ethylene-alt-tetrafluoroethylene) base film with a subsequent co-grafting of styrene and GMA at different ratios. The obtained membranes were sulfonated to introduce proton conducting groups and the epoxide moiety of the GMA unit was hydrolyzed for a better water absorption. The PEM was investigated regarding its structural composition, water uptake and through-plane conductivity. It could be shown that the density of sulfonic acid groups has a higher influence on the proton conductivity of the PEM than an increased water uptake.

  15. Test and intercomparisons of data fitting with general least squares code GMA versus Bayesian code GLUCS

    International Nuclear Information System (INIS)

    Pronyaev, V.G.

    2003-01-01

    Data fitting with GMA and GLUCS gives consistent results. Difference in the evaluated central values obtained with different formalisms can be related to the general accuracy with which fits could be done in different formalisms. It has stochastic nature and should be accounted in the final results of the data evaluation as small SERC uncertainty. Some shift in central values of data evaluated with GLUCS and GMA relative the central values evaluated with the R-matrix model code RAC is observed for cases of fitting strongly varying data and is related to the PPP. The procedure of evaluation, free from PPP, should be elaborated. (author)

  16. Reversible adsorption of catalase onto Fe(3+) chelated poly(AAm-GMA)-IDA cryogels.

    Science.gov (United States)

    Aktaş Uygun, Deniz; Uygun, Murat; Akgöl, Sinan; Denizli, Adil

    2015-05-01

    In this presented study, poly(acrylamide-glycidyl methacrylate) [poly(AAm-GMA)] cryogels were synthesized by cryopolymerization technique at sub-zero temperature. Prepared cryogels were then functionalized with iminodiacetic acid (IDA) and chelated with Fe(3+) ions in order produce the metal chelate affinity matrix. Synthesized cryogels were characterized with FTIR, ESEM and EDX analysis, and it was found that the cryogel had sponge like structure with interconnected pores and their pore diameter was about 200 μm. Fe(3+) chelated poly(AAm-GMA)-IDA cryogels were used for the adsorption of catalase and optimum adsorption conditions were determined by varying the medium pH, initial catalase concentration, temperature and ionic strength. Maximum catalase adsorption onto Fe(3+) chelated poly(AAm-GMA)-IDA cryogel was found to be 12.99 mg/g cryogel at 25 °C, by using pH 5.0 acetate buffer. Adsorbed catalase was removed from the cryogel by using 1.0M of NaCl solution and desorption yield was found to be 96%. Additionally, reusability profile of the Fe(3+) chelated poly(AAm-GMA)-IDA cryogel was also investigated and it was found that, adsorption capacity of the cryogels didn't decrease significantly at the end of the 40 reuses. Catalase activity studies were also tested and it was demonstrated that desorbed catalase retained 70% of its initial activity. Copyright © 2015 Elsevier B.V. All rights reserved.

  17. Preparation of a Bis-GMA-Free Dental Resin System with Synthesized Fluorinated Dimethacrylate Monomers

    Directory of Open Access Journals (Sweden)

    Shuzhen Luo

    2016-12-01

    Full Text Available With the aim of reducing human exposure to Bisphenol A (BPA derivatives in dentistry, a fluorinated dimethacrylate monomer was synthesized to replace 2,2-bis[4-(2-hydroxy-3-methacryloy-loxypropyl-phenyl]propane (Bis-GMA as the base monomer of dental resin. After mixing with reactive diluent triethyleneglycol dimethacrylate (TEGDMA, fluorinated dimethacrylate (FDMA/TEGDMA was prepared and compared with Bis-GMA/TEGDMA in physicochemical properties, such as double bond conversion (DC, volumetric shrinkage (VS, water sorption (WS and solubility (WSL, flexural strength (FS and modulus (FM. The results showed that, when compared with Bis-GMA based resin, FDMA-based resin had several advantages, such as higher DC, lower VS, lower WS, and higher FS after water immersion. All of these revealed that FDMA had potential to be used as a substitute for Bis-GMA. Of course, many more studies, such as biocompatibility testing, should be undertaken to prove whether FDMA could be applied in clinic.

  18. Parallelization of particle transport using Intel® TBB

    International Nuclear Information System (INIS)

    Apostolakis, J; Brun, R; Carminati, F; Gheata, A; Wenzel, S; Belogurov, S; Ovcharenko, E

    2014-01-01

    One of the current challenges in HEP computing is the development of particle propagation algorithms capable of efficiently use all performance aspects of modern computing devices. The Geant-Vector project at CERN has recently introduced an approach in this direction. This paper describes the implementation of a similar workflow using the Intel(r) Threading Building Blocks (Intel(r) TBB) library. This approach is intended to overcome the potential bottleneck of having a single dispatcher on many-core architectures and to result in better scalability compared to the initial pthreads-based version.

  19. MWCNTs/P(St-co-GMA) composite nanofibers of engineered interface chemistry for epoxy matrix nanocomposites.

    Science.gov (United States)

    Özden-Yenigün, Elif; Menceloğlu, Yusuf Z; Papila, Melih

    2012-02-01

    Strengthened nanofiber-reinforced epoxy matrix composites are demonstrated by engineering composite electrospun fibers of multi-walled carbon nanotubes (MWCNTs) and reactive P(St-co-GMA). MWCNTs are incorporated into surface-modified, reactive P(St-co-GMA) nanofibers by electrospinning; functionalization of these MWCNT/P(St-co-GMA) composite nanofibers with epoxide moieties facilitates bonding at the interface of the cross-linked fibers and the epoxy matrix, effectively reinforcing and toughening the epoxy resin. Rheological properties are determined and thermodynamic stabilization is demonstrated for MWCNTs in the P(St-co-GMA)-DMF polymer solution. Homogeneity and uniformity of the fiber formation within the electrospun mats are achieved at polymer concentration of 30 wt %. Results show that the MWCNT fraction decreases the polymer solution viscosity, yielding a narrower fiber diameter. The fiber diameter drops from an average of 630 nm to 460 nm, as the MWCNTs wt fraction (1, 1.5, and 2%) is increased. The electrospun nanofibers of the MWCNTs/P(St-co-GMA) composite are also embedded into an epoxy resin to investigate their reinforcing abilities. A significant increase in the mechanical response is observed, up to >20% in flexural modulus, when compared to neat epoxy, despite a very low composite fiber weight fraction (at about 0.2% by a single-layer fibrous mat). The increase is attributed to the combined effect of the two factors the inherent strength of the well-dispersed MWCNTs and the surface chemistry of the electrospun fibers that have been modified with epoxide to enable cross-linking between the polymer matrix and the nanofibers.

  20. Intel Legend and CERN would build up high speed Internet

    CERN Multimedia

    2002-01-01

    Intel, Legend and China Education and Research Network jointly announced on the 25th of April that they will be cooperating with each other to build up the new generation high speed internet, over the next three years (1/2 page).

  1. Communication overhead on the Intel iPSC-860 hypercube

    Science.gov (United States)

    Bokhari, Shahid H.

    1990-01-01

    Experiments were conducted on the Intel iPSC-860 hypercube in order to evaluate the overhead of interprocessor communication. It is demonstrated that: (1) contrary to popular belief, the distance between two communicating processors has a significant impact on communication time, (2) edge contention can increase communication time by a factor of more than 7, and (3) node contention has no measurable impact.

  2. Connecting Effective Instruction and Technology. Intel-elebration: Safari.

    Science.gov (United States)

    Burton, Larry D.; Prest, Sharon

    Intel-ebration is an attempt to integrate the following research-based instructional frameworks and strategies: (1) dimensions of learning; (2) multiple intelligences; (3) thematic instruction; (4) cooperative learning; (5) project-based learning; and (6) instructional technology. This paper presents a thematic unit on safari, using the…

  3. Using the Intel Math Kernel Library on Peregrine | High-Performance

    Science.gov (United States)

    Computing | NREL the Intel Math Kernel Library on Peregrine Using the Intel Math Kernel Library on Peregrine Learn how to use the Intel Math Kernel Library (MKL) with Peregrine system software. MKL architectures. Core math functions in MKL include BLAS, LAPACK, ScaLAPACK, sparse solvers, fast Fourier

  4. Roofline Analysis in the Intel® Advisor to Deliver Optimized Performance for applications on Intel® Xeon Phi™ Processor

    OpenAIRE

    Koskela, TS; Lobet, M

    2017-01-01

    In this session we show, in two case studies, how the roofline feature of Intel Advisor has been utilized to optimize the performance of kernels of the XGC1 and PICSAR codes in preparation for Intel Knights Landing architecture. The impact of the implemented optimizations and the benefits of using the automatic roofline feature of Intel Advisor to study performance of large applications will be presented. This demonstrates an effective optimization strategy that has enabled these science appl...

  5. Poly(GMA/MA/MBAA) Copolymer Beads: a Highly Efficient Support Immobilizing Penicillin G Acylase

    Institute of Scientific and Technical Information of China (English)

    Ping XUE; Guan Zhong LU; Wan Yi LIU

    2006-01-01

    The hydrophilic, macroporous and beaded ternary copolymer of glycidyl methacrylate (GMA)/methacrylamide(MA)/N,N'-methylene-bis(acrylamide)(MBAA)was synthesized using the industrial agents by inverse suspension polymerization. The apparent activity of the immobilized penicillin G acylase reached 1096 IU/g for hydrolysis penicillin G on the beads with diameter of 0.11-0.13 mm, and it changed hardly after 50 cycles. It can be expected to be a good potential in industrial application.

  6. MILC staggered conjugate gradient performance on Intel KNL

    Energy Technology Data Exchange (ETDEWEB)

    Li, Ruiz [Indiana Univ., Bloomington, IN (United States). Dept. of Physics; Detar, Carleton [Univ. of Utah, Salt Lake City, UT (United States). Dept. of Physics and Astronomy; Doerfler, Douglas W. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). National Energy Research Scientific Computing Center (NERSC); Gottlieb, Steven [Indiana Univ., Bloomington, IN (United States). Dept. of Physics; Jha, Asish [Intel Corp., Hillsboro, OR (United States). Sofware and Services Group; Kalamkar, Dhiraj [Intel Labs., Bangalore (India). Parallel Computing Lab.; Toussaint, Doug [Univ. of Arizona, Tucson, AZ (United States). Physics Dept.

    2016-11-03

    We review our work done to optimize the staggered conjugate gradient (CG) algorithm in the MILC code for use with the Intel Knights Landing (KNL) architecture. KNL is the second gener- ation Intel Xeon Phi processor. It is capable of massive thread parallelism, data parallelism, and high on-board memory bandwidth and is being adopted in supercomputing centers for scientific research. The CG solver consumes the majority of time in production running, so we have spent most of our effort on it. We compare performance of an MPI+OpenMP baseline version of the MILC code with a version incorporating the QPhiX staggered CG solver, for both one-node and multi-node runs.

  7. Vectorization for Molecular Dynamics on Intel Xeon Phi Corpocessors

    Science.gov (United States)

    Yi, Hongsuk

    2014-03-01

    Many modern processors are capable of exploiting data-level parallelism through the use of single instruction multiple data (SIMD) execution. The new Intel Xeon Phi coprocessor supports 512 bit vector registers for the high performance computing. In this paper, we have developed a hierarchical parallelization scheme for accelerated molecular dynamics simulations with the Terfoff potentials for covalent bond solid crystals on Intel Xeon Phi coprocessor systems. The scheme exploits multi-level parallelism computing. We combine thread-level parallelism using a tightly coupled thread-level and task-level parallelism with 512-bit vector register. The simulation results show that the parallel performance of SIMD implementations on Xeon Phi is apparently superior to their x86 CPU architecture.

  8. Full cycle trigonometric function on Intel Quartus II Verilog

    Science.gov (United States)

    Mustapha, Muhazam; Zulkarnain, Nur Antasha

    2018-02-01

    This paper discusses about an improvement of a previous research on hardware based trigonometric calculations. Tangent function will also be implemented to get a complete set. The functions have been simulated using Quartus II where the result will be compared to the previous work. The number of bits has also been extended for each trigonometric function. The design is based on RTL due to its resource efficient nature. At earlier stage, a technology independent test bench simulation was conducted on ModelSim due to its convenience in capturing simulation data so that accuracy information can be obtained. On second stage, Intel/Altera Quartus II will be used to simulate on technology dependent platform, particularly on the one belonging to Intel/Altera itself. Real data on no. logic elements used and propagation delay have also been obtained.

  9. Porting FEASTFLOW to the Intel Xeon Phi: Lessons Learned

    OpenAIRE

    Georgios Goumas

    2014-01-01

    In this paper we report our experiences in porting the FEASTFLOW software infrastructure to the Intel Xeon Phi coprocessor. Our efforts involved both the evaluation of programming models including OpenCL, POSIX threads and OpenMP and typical optimization strategies like parallelization and vectorization. Since the straightforward porting process of the already existing OpenCL version of the code encountered performance problems that require further analysis, we focused our efforts on the impl...

  10. Protein Alignment on the Intel Xeon Phi Coprocessor

    OpenAIRE

    Ramstad, Jorun

    2015-01-01

    There is an increasing need for sensitive, high perfomance sequence alignemnet tools. With the growing databases of scientificly analyzed protein sequences, more compute power is necessary. Specialized architectures arise, and a transition from serial to specialized implementationsis is required. This thesis is a study of whether Intel 60's cores Xeon Phi coprocessor is a suitable architecture for implementation of a sequence alignment tool. The performance relative to existing tools are eval...

  11. Staggered Dslash Performance on Intel Xeon Phi Architecture

    OpenAIRE

    Li, Ruizi; Gottlieb, Steven

    2014-01-01

    The conjugate gradient (CG) algorithm is among the most essential and time consuming parts of lattice calculations with staggered quarks. We test the performance of CG and dslash, the key step in the CG algorithm, on the Intel Xeon Phi, also known as the Many Integrated Core (MIC) architecture. We try different parallelization strategies using MPI, OpenMP, and the vector processing units (VPUs).

  12. Intel·ligència emocional a maternal

    OpenAIRE

    Missé Cortina, Jordi

    2015-01-01

    Inclusió d'activitats d'intel·ligència emocional a maternal A i B per al treball de l'adquisició de valors com l'autoestima, el respecte, la tolerància, etc. Inclusión de actividades de inteligencia emocional en maternal A y B para el trabajo de la adquisición de valores como la autoestima, el respeto, la tolerancia, etc. Practicum for the Psychology program on Educational Psychology.

  13. Performance of Artificial Intelligence Workloads on the Intel Core 2 Duo Series Desktop Processors

    Directory of Open Access Journals (Sweden)

    Abdul Kareem PARCHUR

    2010-12-01

    Full Text Available As the processor architecture becomes more advanced, Intel introduced its Intel Core 2 Duo series processors. Performance impact on Intel Core 2 Duo processors are analyzed using SPEC CPU INT 2006 performance numbers. This paper studied the behavior of Artificial Intelligence (AI benchmarks on Intel Core 2 Duo series processors. Moreover, we estimated the task completion time (TCT @1 GHz, @2 GHz and @3 GHz Intel Core 2 Duo series processors frequency. Our results show the performance scalability in Intel Core 2 Duo series processors. Even though AI benchmarks have similar execution time, they have dissimilar characteristics which are identified using principal component analysis and dendogram. As the processor frequency increased from 1.8 GHz to 3.167 GHz the execution time is decreased by ~370 sec for AI workloads. In the case of Physics/Quantum Computing programs it was ~940 sec.

  14. Comparison of Processor Performance of SPECint2006 Benchmarks of some Intel Xeon Processors

    OpenAIRE

    Abdul Kareem PARCHUR; Ram Asaray SINGH

    2012-01-01

    High performance is a critical requirement to all microprocessors manufacturers. The present paper describes the comparison of performance in two main Intel Xeon series processors (Type A: Intel Xeon X5260, X5460, E5450 and L5320 and Type B: Intel Xeon X5140, 5130, 5120 and E5310). The microarchitecture of these processors is implemented using the basis of a new family of processors from Intel starting with the Pentium 4 processor. These processors can provide a performance boost for many ke...

  15. Does the Intel Xeon Phi processor fit HEP workloads?

    Science.gov (United States)

    Nowak, A.; Bitzes, G.; Dotti, A.; Lazzaro, A.; Jarp, S.; Szostek, P.; Valsan, L.; Botezatu, M.; Leduc, J.

    2014-06-01

    This paper summarizes the five years of CERN openlab's efforts focused on the Intel Xeon Phi co-processor, from the time of its inception to public release. We consider the architecture of the device vis a vis the characteristics of HEP software and identify key opportunities for HEP processing, as well as scaling limitations. We report on improvements and speedups linked to parallelization and vectorization on benchmarks involving software frameworks such as Geant4 and ROOT. Finally, we extrapolate current software and hardware trends and project them onto accelerators of the future, with the specifics of offline and online HEP processing in mind.

  16. Does the Intel Xeon Phi processor fit HEP workloads?

    International Nuclear Information System (INIS)

    Nowak, A; Bitzes, G; Dotti, A; Lazzaro, A; Jarp, S; Szostek, P; Valsan, L; Botezatu, M; Leduc, J

    2014-01-01

    This paper summarizes the five years of CERN openlab's efforts focused on the Intel Xeon Phi co-processor, from the time of its inception to public release. We consider the architecture of the device vis a vis the characteristics of HEP software and identify key opportunities for HEP processing, as well as scaling limitations. We report on improvements and speedups linked to parallelization and vectorization on benchmarks involving software frameworks such as Geant4 and ROOT. Finally, we extrapolate current software and hardware trends and project them onto accelerators of the future, with the specifics of offline and online HEP processing in mind.

  17. In vitro blood and fibroblast responses to BisGMA-TEGDMA/bioactive glass composite implants.

    Science.gov (United States)

    Abdulmajeed, Aous A; Kokkari, Anne K; Käpylä, Jarmo; Massera, Jonathan; Hupa, Leena; Vallittu, Pekka K; Närhi, Timo O

    2014-01-01

    This in vitro study was designed to evaluate both blood and human gingival fibroblast responses to bisphenol A-glycidyl methacrylate-triethyleneglycol dimethacrylate (BisGMA-TEGDMA)/bioactive glass (BAG) composite, aimed to be used as composite implant abutment surface modifier. Three different types of substrates were investigated: (a) plain polymer (BisGMA 50 wt%-TEGDMA 50 wt%), (b) BAG-composite (50 wt% polymer + 50 wt% fraction of BAG-particles, <50 μm), and (c) plain BAG plates (100 wt% BAG). The blood response, including the blood-clotting ability and platelet adhesion morphology were evaluated. Human gingival fibroblasts were plated and cultured on the experimental substrates for up to 10 days, then the cell proliferation rate was assessed using AlamarBlue assay™. The BAG-composite and plain BAG substrates had a shorter clotting time than plain polymer substrates. Platelet activation and aggregation were most extensive, qualitatively, on BAG-composite. Analysis of the normalized cell proliferation rate on the different surfaces showed some variations throughout the experiment, however, by day 10 the BAG-composite substrate showed the highest (P < 0.001) cell proliferation rate. In conclusion, the presence of exposed BAG-particles enhances fibroblast and blood responses on composite surfaces in vitro.

  18. Exploring synchrotron radiation capabilities: The ALS-Intel CRADA

    International Nuclear Information System (INIS)

    Gozzo, F.; Cossy-Favre, A.; Padmore, H.

    1997-01-01

    Synchrotron radiation spectroscopy and spectromicroscopy were applied, at the Advanced Light Source, to the analysis of materials and problems of interest to the commercial semiconductor industry. The authors discuss some of the results obtained at the ALS using existing capabilities, in particular the small spot ultra-ESCA instrument on beamline 7.0 and the AMS (Applied Material Science) endstation on beamline 9.3.2. The continuing trend towards smaller feature size and increased performance for semiconductor components has driven the semiconductor industry to invest in the development of sophisticated and complex instrumentation for the characterization of microstructures. Among the crucial milestones established by the Semiconductor Industry Association are the needs for high quality, defect free and extremely clean silicon wafers, very thin gate oxides, lithographies near 0.1 micron and advanced material interconnect structures. The requirements of future generations cannot be met with current industrial technologies. The purpose of the ALS-Intel CRADA (Cooperative Research And Development Agreement) is to explore, compare and improve the utility of synchrotron-based techniques for practical analysis of substrates of interest to semiconductor chip manufacturing. The first phase of the CRADA project consisted in exploring existing ALS capabilities and techniques on some problems of interest. Some of the preliminary results obtained on Intel samples are discussed here

  19. Evaluation of the Intel Westmere-EX server processor

    CERN Document Server

    Jarp, S; Leduc, J; Nowak, A; CERN. Geneva. IT Department

    2011-01-01

    One year after the arrival of the Intel Xeon 7500 systems (“Nehalem-EX”), CERN openlab is presenting a set of benchmark results obtained when running on the new Xeon E7-4870 Processors, representing the “Westmere-EX” family. A modern 4-socket, 40-core system is confronted with the previous generation of expandable (“EX”) platforms, represented by a 4-socket, 32-core Intel Xeon X7560 based system – both being “top of the line” systems. Benchmarking of modern processors is a very complex affair. One has to control (at least) the following features: processor frequency, overclocking via Turbo mode, the number of physical cores in use, the use of logical cores via Symmetric MultiThreading (SMT), the cache sizes available, the configured memory topology, as well as the power configuration if throughput per watt is to be measured. As in previous activities, we have tried to do a good job of comparing like with like. In a “top of the line” comparison based on the HEPSPEC06 benchmark, the “We...

  20. Global synchronization algorithms for the Intel iPSC/860

    Science.gov (United States)

    Seidel, Steven R.; Davis, Mark A.

    1992-01-01

    In a distributed memory multicomputer that has no global clock, global processor synchronization can only be achieved through software. Global synchronization algorithms are used in tridiagonal systems solvers, CFD codes, sequence comparison algorithms, and sorting algorithms. They are also useful for event simulation, debugging, and for solving mutual exclusion problems. For the Intel iPSC/860 in particular, global synchronization can be used to ensure the most effective use of the communication network for operations such as the shift, where each processor in a one-dimensional array or ring concurrently sends a message to its right (or left) neighbor. Three global synchronization algorithms are considered for the iPSC/860: the gysnc() primitive provided by Intel, the PICL primitive sync0(), and a new recursive doubling synchronization (RDS) algorithm. The performance of these algorithms is compared to the performance predicted by communication models of both the long and forced message protocols. Measurements of the cost of shift operations preceded by global synchronization show that the RDS algorithm always synchronizes the nodes more precisely and costs only slightly more than the other two algorithms.

  1. Lawrence Livermore National Laboratory selects Intel Itanium 2 processors for world's most powerful Linux cluster

    CERN Multimedia

    2003-01-01

    "Intel Corporation, system manufacturer California Digital and the University of California at Lawrence Livermore National Laboratory (LLNL) today announced they are building one of the world's most powerful supercomputers. The supercomputer project, codenamed "Thunder," uses nearly 4,000 Intel® Itanium® 2 processors... is expected to be complete in January 2004" (1 page).

  2. 75 FR 48338 - Intel Corporation; Analysis of Proposed Consent Order to Aid Public Comment

    Science.gov (United States)

    2010-08-10

    ... product road maps, its compilers, and product benchmarking (Sections VI, VII, and VIII). The Proposed... alleges that Intel's failure to fully disclose the changes it made to its compilers and libraries... benchmarking organizations the effects of its compiler redesign on non-Intel CPUs. Several benchmarking...

  3. Efficient Implementation of Many-body Quantum Chemical Methods on the Intel Xeon Phi Coprocessor

    Energy Technology Data Exchange (ETDEWEB)

    Apra, Edoardo; Klemm, Michael; Kowalski, Karol

    2014-12-01

    This paper presents the implementation and performance of the highly accurate CCSD(T) quantum chemistry method on the Intel Xeon Phi coprocessor within the context of the NWChem computational chemistry package. The widespread use of highly correlated methods in electronic structure calculations is contingent upon the interplay between advances in theory and the possibility of utilizing the ever-growing computer power of emerging heterogeneous architectures. We discuss the design decisions of our implementation as well as the optimizations applied to the compute kernels and data transfers between host and coprocessor. We show the feasibility of adopting the Intel Many Integrated Core Architecture and the Intel Xeon Phi coprocessor for developing efficient computational chemistry modeling tools. Remarkable scalability is demonstrated by benchmarks. Our solution scales up to a total of 62560 cores with the concurrent utilization of Intel Xeon processors and Intel Xeon Phi coprocessors.

  4. Analysis OpenMP performance of AMD and Intel architecture for breaking waves simulation using MPS

    Science.gov (United States)

    Alamsyah, M. N. A.; Utomo, A.; Gunawan, P. H.

    2018-03-01

    Simulation of breaking waves by using Navier-Stokes equation via moving particle semi-implicit method (MPS) over close domain is given. The results show the parallel computing on multicore architecture using OpenMP platform can reduce the computational time almost half of the serial time. Here, the comparison using two computer architectures (AMD and Intel) are performed. The results using Intel architecture is shown better than AMD architecture in CPU time. However, in efficiency, the computer with AMD architecture gives slightly higher than the Intel. For the simulation by 1512 number of particles, the CPU time using Intel and AMD are 12662.47 and 28282.30 respectively. Moreover, the efficiency using similar number of particles, AMD obtains 50.09 % and Intel up to 49.42 %.

  5. Visible light cure characteristics of a cycloaliphatic polyester dimethacrylate alternative oligomer to bisGMA.

    Science.gov (United States)

    Vaidyanathan, Tritala K; Vaidyanathan, Jayalakshmi

    2015-12-01

    Objective : The goal of this study was to characterize the light curing characteristics of a new oligomer PEM-665 designed to be used as an alternative monomer to BisGMA. Materials and methods : PEM-665 (P) and BisGMA (B) solutions were prepared with triethylene glycol dimethacrylate (T) diluent in different weight proportions (70/30 and 50/50). Solutions containing 70% P and 30% T were designated as 70PT, 70%B and 30%T as 70BT, 50%P and 50%T as 50PT and 50%B and 50%T as 50BT. The initiators were CQ (EDMAB was used as amine accelerator for CQ) and DPO in 1% concentration. Eight solutions were prepared in a factorial design: 70PT/DPO; 70PT/CQ; 50PT/DPO; 50PT/CQ; 70BT/DPO; 70BT/CQ; 50BT/DPO; 50BT/CQ. BISCO VIP visible light was used to cure the monomer solutions using 30 s exposure time and 400 W power setting. TA Instruments Differential Scanning Calorimeter (DSC 2910) was used to determine the heat of cure (J/g) during polymerization at 37 °C, from which molar heat of cure (kJ/mole) and %Conversion values were estimated. Results : Range of mean values as a function monomer selections were: heat of cure (J/g): 161.7 for 70PT/DPO system to 198.6 for 50BT/CQ system; molar heat of cure (kJ/mole): 67.3 for 70BT/DPO to 78.86 for 50PT/CQ; % conversion: 59.9 for 70BT/DPO to 70.3 for 50PT/CQ. Analysis of variance and Tukey HSD pairwise contrast showed statistically significant differences between % conversion means of PEM and BisGMA mixtures, with PEM mixtures showing significantly higher mean values. Conclusions : The results suggest that PEM-665 is a promising candidate material for dental polymer applications.

  6. Performance of R-GMA based grid job monitoring system for CMS data production

    CERN Document Server

    Byrom, Robert; Fisher, Steve M; Grandi, Claudio; Hobson, Peter R; Kyberd, Paul; MacEvoy, Barry; Nebrensky, Jindrich Josef; Tallini, Hugh; Traylen, Stephen

    2004-01-01

    High Energy Physics experiments, such as the Compact Muon Solenoid (CMS) at the CERN laboratory in Geneva, have large-scale data processing requirements, with stored data accumulating at a rate of 1 Gbyte/s. This load comfortably exceeds any previous processing requirements and we believe it may be most efficiently satisfied through Grid computing. Management of large Monte Carlo productions (~3000 jobs) or data analyses and the quality assurance of the results requires careful monitoring and bookkeeping, and an important requirement when using the Grid is the ability to monitor transparently the large number of jobs that are being executed simultaneously at multiple remote sites. R-GMA is a monitoring and information management service for distributed resources based on the Grid Monitoring Architecture of the Global Grid Forum. We have previously developed a system allowing us to test its performance under a heavy load while using few real Grid resources. We present the latest results on this system and comp...

  7. A Non-Intrusive GMA Welding Process Quality Monitoring System Using Acoustic Sensing.

    Science.gov (United States)

    Cayo, Eber Huanca; Alfaro, Sadek Crisostomo Absi

    2009-01-01

    Most of the inspection methods used for detection and localization of welding disturbances are based on the evaluation of some direct measurements of welding parameters. This direct measurement requires an insertion of sensors during the welding process which could somehow alter the behavior of the metallic transference. An inspection method that evaluates the GMA welding process evolution using a non-intrusive process sensing would allow not only the identification of disturbances during welding runs and thus reduce inspection time, but would also reduce the interference on the process caused by the direct sensing. In this paper a nonintrusive method for weld disturbance detection and localization for weld quality evaluation is demonstrated. The system is based on the acoustic sensing of the welding electrical arc. During repetitive tests in welds without disturbances, the stability acoustic parameters were calculated and used as comparison references for the detection and location of disturbances during the weld runs.

  8. 75 FR 21353 - Intel Corporation, Fab 20 Division, Including On-Site Leased Workers From Volt Technical...

    Science.gov (United States)

    2010-04-23

    ... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-73,642] Intel Corporation, Fab 20... of Intel Corporation, Fab 20 Division, including on-site leased workers of Volt Technical Resources... Precision, Inc. were employed on-site at the Hillsboro, Oregon location of Intel Corporation, Fab 20...

  9. Influence of ionizing radiation on the mechanical properties of BisGMA/TEGDMA based experimental resin

    International Nuclear Information System (INIS)

    LMP, Campos; Boaro, LC; LKG, Santos; Parra, DF; Lugão, AB

    2015-01-01

    Dental restorative composites are activated by visible light and the polymerization process, known as direct technique, is initiated by absorbing light in a specific wavelength range (450–500 nm). However this technique presented some disadvantages. If light is not inserted correctly, layers uncured can cause countless damage to restoration, especially with regard to mechanical properties. A clinical alternative used to reduce the shortcomings of direct application is the use of composite resins for indirect application. These composites are adaptations of resins prepared for direct use, with differences mainly in the healing process. Besides the traditional photoactivation, indirect application composites may be submitted to particular curing conditions, such as a slow curing rate, heating, vacuum, and inert-gas pressure leading to an oxygen-free environment. However few studies have been conducted on the process of post-curing by ionizing radiation at low doses. On this sense the purpose of this study was to evaluate possible interactions of ionizing radiation in the post-curing process of the experimental composites based on BisGMA/TEGDMA filled with silica Aerosil OX-50 silanized. Characterization of the experimental composites was performed by thermogravimetry analysis, infrared spectroscopy, elastic modulus and flexural strength. Statistical analysis of results was calculated by one-way ANOVA/Tukey's test. Cross-linking of the polymeric matrix caused by ionizing radiation, influenced the thermal stability of irradiated specimens. FTIR analysis showed that the ionizing radiation induced a post-cure reaction in the specimens. The irradiation dose influenced directly the mechanical properties that showed a strong positive correlation between flexural strength and irradiation and between modulus strength and irradiation. - Highlights: • Interactions of ionizing radiation in BisGMA/TEGDMA experimental dental composites filled with sylanized silica.

  10. BisGMA-polyvinylpyrrolidone blend based nanocomposites reinforced with chitosan grafted f-multiwalled carbon nanotubes

    Directory of Open Access Journals (Sweden)

    A. Praharaj

    2015-01-01

    Full Text Available In this work, initially a non-destroyable surface grafting of acid functionalized multiwalled carbon nanotubes (f-MWCNTs with biopolymer chitosan (CS was carried out using glutaraldehyde as a cross-linking agent via the controlled covalent deposition method which was characterized by Fourier transform infrared spectroscopy (FTIR and scanning electron microscopy (SEM. Then, BisGMA (bisphenol-A glycidyldimethacrylate-polyvinylpyrrolidone (PVP blend was prepared (50:50 wt% by a simple sonication method. The CS grafted f-MWCNTs (CS/f-MWCNTs were finally dispersed in BisGMA-PVP blend (BGP50 system in different compositions i.e. 0, 2, 5 and 7 wt% and pressed into molds for the fabrication of reinforced nanocomposites which were characterized by SEM. Nanocomposites reinforced with 2 wt% raw MWCNTs and acid f-MWCNTs were also fabricated and their properties were studied in detail. The results of comparative study report lower values of the investigated properties in nanocomposites with 2 wt% raw and f-MWCNTs than the one with 2 wt% CS/f-MWCNTs proving it to be a better reinforcing nanofiller. Further, the mechanical behavior of the nanocomposites with various CS/f-MWCNTs content showed a dramatic increase in Young’s Modulus, tensile strength, impact strength and hardness along with improved dynamic mechanical, thermal and electrical properties at 5 wt% content of CS/f-MWCNTs. The addition of CS/f-MWCNTs also resulted in reduced corrosion and swelling properties. Thus, the fabricated nanocomposites with optimum nanofiller content could serve as low cost and light weight structural, thermal and electrical materials compatible in various corrosive and solvent based environments.

  11. Studies on preparing and adsorption property of grafting terpolymer microbeads of PEI-GMA/AM/MBA for bilirubin.

    Science.gov (United States)

    Gao, Baojiao; Lei, Haibo; Jiang, Liding; Zhu, Yong

    2007-06-15

    Crosslinking copolymer microbeads with a diameter range of 100-150 microm were synthesized by suspension copolymerization of glycidyl methacrylate (GMA), acrylamide (AM) and N,N'-methylene bisacrylamide (MBA). Subsequently, polyethyleneimine (PEI) was grafted on the surfaces of the terpolymer microbeads GMA/AM/MBA via the ring-opening reaction of the epoxy groups, and the grafting microbeads PEI-GMA/AM/MBA were prepared. In this paper, the adsorption property of the grafting microbeads for bilirubin was mainly investigated, and the effects of various factors, such as pH value, ionic strength and grafting degree of PEI on the surface of grafting microbeads and the adsorption capacity of the grafting microbeads for bilirubin were examined. The batch adsorption experiment results show that by right of the action of grafted polyamine macromolecules PEI, the grafting microbeads PEI-GMA/AM/MBA have quite strong adsorption ability for bilirubin; the isotherm adsorption conforms to Freundlich equation. The pH value of the medium affects the adsorption capacity greatly, As in the nearly neutral solutions with pH 6, the grafting microbeads have the strongest adsorption ability for bilirubin, whereas in acidic and basic solutions their adsorption ability is weak. The ionic strength hardly affects the adsorption ability of the grafting microbeads. The grafting degree of PEI on the surfaces of the grafting microbeads also has a great effect on the adsorption capacity, and higher the grafting degree of PEI on the surface of the microbead PEI-GMA/AM/MBA, the stronger is the adsorption ability of the microbeads.

  12. Comparison of Processor Performance of SPECint2006 Benchmarks of some Intel Xeon Processors

    Directory of Open Access Journals (Sweden)

    Abdul Kareem PARCHUR

    2012-08-01

    Full Text Available High performance is a critical requirement to all microprocessors manufacturers. The present paper describes the comparison of performance in two main Intel Xeon series processors (Type A: Intel Xeon X5260, X5460, E5450 and L5320 and Type B: Intel Xeon X5140, 5130, 5120 and E5310. The microarchitecture of these processors is implemented using the basis of a new family of processors from Intel starting with the Pentium 4 processor. These processors can provide a performance boost for many key application areas in modern generation. The scaling of performance in two major series of Intel Xeon processors (Type A: Intel Xeon X5260, X5460, E5450 and L5320 and Type B: Intel Xeon X5140, 5130, 5120 and E5310 has been analyzed using the performance numbers of 12 CPU2006 integer benchmarks, performance numbers that exhibit significant differences in performance. The results and analysis can be used by performance engineers, scientists and developers to better understand the performance scaling in modern generation processors.

  13. Performance of a plasma fluid code on the Intel parallel computers

    International Nuclear Information System (INIS)

    Lynch, V.E.; Carreras, B.A.; Drake, J.B.; Leboeuf, J.N.; Liewer, P.

    1992-01-01

    One approach to improving the real-time efficiency of plasma turbulence calculations is to use a parallel algorithm. A parallel algorithm for plasma turbulence calculations was tested on the Intel iPSC/860 hypercube and the Touchtone Delta machine. Using the 128 processors of the Intel iPSC/860 hypercube, a factor of 5 improvement over a single-processor CRAY-2 is obtained. For the Touchtone Delta machine, the corresponding improvement factor is 16. For plasma edge turbulence calculations, an extrapolation of the present results to the Intel σ machine gives an improvement factor close to 64 over the single-processor CRAY-2

  14. Performance of a plasma fluid code on the Intel parallel computers

    International Nuclear Information System (INIS)

    Lynch, V.E.; Carreras, B.A.; Drake, J.B.; Leboeuf, J.N.; Liewer, P.

    1992-01-01

    One approach to improving the real-time efficiency of plasma turbulence calculations is to use a parallel algorithm. A parallel algorithm for plasma turbulence calculations was tested on the Intel iPSC/860 hypercube and the Touchtone Delta machine. Using the 128 processors of the Intel iPSC/860 hypercube, a factor of 5 improvement over a single-processor CRAY-2 is obtained. For the Touchtone Delta machine, the corresponding improvement factor is 16. For plasma edge turbulence calculations, an extrapolation of the present results to the Intel (sigma) machine gives an improvement factor close to 64 over the single-processor CRAY-2. 12 refs

  15. Performance of a plasma fluid code on the Intel parallel computers

    Science.gov (United States)

    Lynch, V. E.; Carreras, B. A.; Drake, J. B.; Leboeuf, J. N.; Liewer, P.

    1992-01-01

    One approach to improving the real-time efficiency of plasma turbulence calculations is to use a parallel algorithm. A parallel algorithm for plasma turbulence calculations was tested on the Intel iPSC/860 hypercube and the Touchtone Delta machine. Using the 128 processors of the Intel iPSC/860 hypercube, a factor of 5 improvement over a single-processor CRAY-2 is obtained. For the Touchtone Delta machine, the corresponding improvement factor is 16. For plasma edge turbulence calculations, an extrapolation of the present results to the Intel (sigma) machine gives an improvement factor close to 64 over the single-processor CRAY-2.

  16. Applications Performance on NAS Intel Paragon XP/S - 15#

    Science.gov (United States)

    Saini, Subhash; Simon, Horst D.; Copper, D. M. (Technical Monitor)

    1994-01-01

    The Numerical Aerodynamic Simulation (NAS) Systems Division received an Intel Touchstone Sigma prototype model Paragon XP/S- 15 in February, 1993. The i860 XP microprocessor with an integrated floating point unit and operating in dual -instruction mode gives peak performance of 75 million floating point operations (NIFLOPS) per second for 64 bit floating point arithmetic. It is used in the Paragon XP/S-15 which has been installed at NAS, NASA Ames Research Center. The NAS Paragon has 208 nodes and its peak performance is 15.6 GFLOPS. Here, we will report on early experience using the Paragon XP/S- 15. We have tested its performance using both kernels and applications of interest to NAS. We have measured the performance of BLAS 1, 2 and 3 both assembly-coded and Fortran coded on NAS Paragon XP/S- 15. Furthermore, we have investigated the performance of a single node one-dimensional FFT, a distributed two-dimensional FFT and a distributed three-dimensional FFT Finally, we measured the performance of NAS Parallel Benchmarks (NPB) on the Paragon and compare it with the performance obtained on other highly parallel machines, such as CM-5, CRAY T3D, IBM SP I, etc. In particular, we investigated the following issues, which can strongly affect the performance of the Paragon: a. Impact of the operating system: Intel currently uses as a default an operating system OSF/1 AD from the Open Software Foundation. The paging of Open Software Foundation (OSF) server at 22 MB to make more memory available for the application degrades the performance. We found that when the limit of 26 NIB per node out of 32 MB available is reached, the application is paged out of main memory using virtual memory. When the application starts paging, the performance is considerably reduced. We found that dynamic memory allocation can help applications performance under certain circumstances. b. Impact of data cache on the i860/XP: We measured the performance of the BLAS both assembly coded and Fortran

  17. Single event effect testing of the Intel 80386 family and the 80486 microprocessor

    International Nuclear Information System (INIS)

    Moran, A.; LaBel, K.; Gates, M.; Seidleck, C.; McGraw, R.; Broida, M.; Firer, J.; Sprehn, S.

    1996-01-01

    The authors present single event effect test results for the Intel 80386 microprocessor, the 80387 coprocessor, the 82380 peripheral device, and on the 80486 microprocessor. Both single event upset and latchup conditions were monitored

  18. CAMSHIFT Tracker Design Experiments With Intel OpenCV and SAI

    National Research Council Canada - National Science Library

    Francois, Alexandre R

    2004-01-01

    ... (including multi-modal) systems, must be specifically addressed. This report describes design and implementation experiments for CAMSHIFT-based tracking systems using Intel's Open Computer Vision library and SAI...

  19. Multi-threaded ATLAS simulation on Intel Knights Landing processors

    Science.gov (United States)

    Farrell, Steven; Calafiura, Paolo; Leggett, Charles; Tsulaia, Vakhtang; Dotti, Andrea; ATLAS Collaboration

    2017-10-01

    The Knights Landing (KNL) release of the Intel Many Integrated Core (MIC) Xeon Phi line of processors is a potential game changer for HEP computing. With 72 cores and deep vector registers, the KNL cards promise significant performance benefits for highly-parallel, compute-heavy applications. Cori, the newest supercomputer at the National Energy Research Scientific Computing Center (NERSC), was delivered to its users in two phases with the first phase online at the end of 2015 and the second phase now online at the end of 2016. Cori Phase 2 is based on the KNL architecture and contains over 9000 compute nodes with 96GB DDR4 memory. ATLAS simulation with the multithreaded Athena Framework (AthenaMT) is a good potential use-case for the KNL architecture and supercomputers like Cori. ATLAS simulation jobs have a high ratio of CPU computation to disk I/O and have been shown to scale well in multi-threading and across many nodes. In this paper we will give an overview of the ATLAS simulation application with details on its multi-threaded design. Then, we will present a performance analysis of the application on KNL devices and compare it to a traditional x86 platform to demonstrate the capabilities of the architecture and evaluate the benefits of utilizing KNL platforms like Cori for ATLAS production.

  20. Performance optimization of Qbox and WEST on Intel Knights Landing

    Science.gov (United States)

    Zheng, Huihuo; Knight, Christopher; Galli, Giulia; Govoni, Marco; Gygi, Francois

    We present the optimization of electronic structure codes Qbox and WEST targeting the Intel®Xeon Phi™processor, codenamed Knights Landing (KNL). Qbox is an ab-initio molecular dynamics code based on plane wave density functional theory (DFT) and WEST is a post-DFT code for excited state calculations within many-body perturbation theory. Both Qbox and WEST employ highly scalable algorithms which enable accurate large-scale electronic structure calculations on leadership class supercomputer platforms beyond 100,000 cores, such as Mira and Theta at the Argonne Leadership Computing Facility. In this work, features of the KNL architecture (e.g. hierarchical memory) are explored to achieve higher performance in key algorithms of the Qbox and WEST codes and to develop a road-map for further development targeting next-generation computing architectures. In particular, the optimizations of the Qbox and WEST codes on the KNL platform will target efficient large-scale electronic structure calculations of nanostructured materials exhibiting complex structures and prediction of their electronic and thermal properties for use in solar and thermal energy conversion device. This work was supported by MICCoM, as part of Comp. Mats. Sci. Program funded by the U.S. DOE, Office of Sci., BES, MSE Division. This research used resources of the ALCF, which is a DOE Office of Sci. User Facility under Contract DE-AC02-06CH11357.

  1. Multi-threaded ATLAS simulation on Intel Knights Landing processors

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00014247; The ATLAS collaboration; Calafiura, Paolo; Leggett, Charles; Tsulaia, Vakhtang; Dotti, Andrea

    2017-01-01

    The Knights Landing (KNL) release of the Intel Many Integrated Core (MIC) Xeon Phi line of processors is a potential game changer for HEP computing. With 72 cores and deep vector registers, the KNL cards promise significant performance benefits for highly-parallel, compute-heavy applications. Cori, the newest supercomputer at the National Energy Research Scientific Computing Center (NERSC), was delivered to its users in two phases with the first phase online at the end of 2015 and the second phase now online at the end of 2016. Cori Phase 2 is based on the KNL architecture and contains over 9000 compute nodes with 96GB DDR4 memory. ATLAS simulation with the multithreaded Athena Framework (AthenaMT) is a good potential use-case for the KNL architecture and supercomputers like Cori. ATLAS simulation jobs have a high ratio of CPU computation to disk I/O and have been shown to scale well in multi-threading and across many nodes. In this paper we will give an overview of the ATLAS simulation application with detai...

  2. Multi-threaded ATLAS Simulation on Intel Knights Landing Processors

    CERN Document Server

    Farrell, Steven; The ATLAS collaboration; Calafiura, Paolo; Leggett, Charles

    2016-01-01

    The Knights Landing (KNL) release of the Intel Many Integrated Core (MIC) Xeon Phi line of processors is a potential game changer for HEP computing. With 72 cores and deep vector registers, the KNL cards promise significant performance benefits for highly-parallel, compute-heavy applications. Cori, the newest supercomputer at the National Energy Research Scientific Computing Center (NERSC), will be delivered to its users in two phases with the first phase online now and the second phase expected in mid-2016. Cori Phase 2 will be based on the KNL architecture and will contain over 9000 compute nodes with 96GB DDR4 memory. ATLAS simulation with the multithreaded Athena Framework (AthenaMT) is a great use-case for the KNL architecture and supercomputers like Cori. Simulation jobs have a high ratio of CPU computation to disk I/O and have been shown to scale well in multi-threading and across many nodes. In this presentation we will give an overview of the ATLAS simulation application with details on its multi-thr...

  3. Evaluation of the Intel Sandy Bridge-EP server processor

    CERN Document Server

    Jarp, S; Leduc, J; Nowak, A; CERN. Geneva. IT Department

    2012-01-01

    In this paper we report on a set of benchmark results recently obtained by CERN openlab when comparing an 8-core “Sandy Bridge-EP” processor with Intel’s previous microarchitecture, the “Westmere-EP”. The Intel marketing names for these processors are “Xeon E5-2600 processor series” and “Xeon 5600 processor series”, respectively. Both processors are produced in a 32nm process, and both platforms are dual-socket servers. Multiple benchmarks were used to get a good understanding of the performance of the new processor. We used both industry-standard benchmarks, such as SPEC2006, and specific High Energy Physics benchmarks, representing both simulation of physics detectors and data analysis of physics events. Before summarizing the results we must stress the fact that benchmarking of modern processors is a very complex affair. One has to control (at least) the following features: processor frequency, overclocking via Turbo mode, the number of physical cores in use, the use of logical cores ...

  4. Evaluation of the Intel Nehalem-EX server processor

    CERN Document Server

    Jarp, S; Leduc, J; Nowak, A; CERN. Geneva. IT Department

    2010-01-01

    In this paper we report on a set of benchmark results recently obtained by the CERN openlab by comparing the 4-socket, 32-core Intel Xeon X7560 server with the previous generation 4-socket server, based on the Xeon X7460 processor. The Xeon X7560 processor represents a major change in many respects, especially the memory sub-system, so it was important to make multiple comparisons. In most benchmarks the two 4-socket servers were compared. It should be underlined that both servers represent the “top of the line” in terms of frequency. However, in some cases, it was important to compare systems that integrated the latest processor features, such as QPI links, Symmetric multithreading and over-clocking via Turbo mode, and in such situations the X7560 server was compared to a dual socket L5520 based system with an identical frequency of 2.26 GHz. Before summarizing the results we must stress the fact that benchmarking of modern processors is a very complex affair. One has to control (at least) the following ...

  5. Performance Characterization of Multi-threaded Graph Processing Applications on Intel Many-Integrated-Core Architecture

    OpenAIRE

    Liu, Xu; Chen, Langshi; Firoz, Jesun S.; Qiu, Judy; Jiang, Lei

    2017-01-01

    Intel Xeon Phi many-integrated-core (MIC) architectures usher in a new era of terascale integration. Among emerging killer applications, parallel graph processing has been a critical technique to analyze connected data. In this paper, we empirically evaluate various computing platforms including an Intel Xeon E5 CPU, a Nvidia Geforce GTX1070 GPU and an Xeon Phi 7210 processor codenamed Knights Landing (KNL) in the domain of parallel graph processing. We show that the KNL gains encouraging per...

  6. Adaptation of MPDATA Heterogeneous Stencil Computation to Intel Xeon Phi Coprocessor

    Directory of Open Access Journals (Sweden)

    Lukasz Szustak

    2015-01-01

    Full Text Available The multidimensional positive definite advection transport algorithm (MPDATA belongs to the group of nonoscillatory forward-in-time algorithms and performs a sequence of stencil computations. MPDATA is one of the major parts of the dynamic core of the EULAG geophysical model. In this work, we outline an approach to adaptation of the 3D MPDATA algorithm to the Intel MIC architecture. In order to utilize available computing resources, we propose the (3 + 1D decomposition of MPDATA heterogeneous stencil computations. This approach is based on combination of the loop tiling and fusion techniques. It allows us to ease memory/communication bounds and better exploit the theoretical floating point efficiency of target computing platforms. An important method of improving the efficiency of the (3 + 1D decomposition is partitioning of available cores/threads into work teams. It permits for reducing inter-cache communication overheads. This method also increases opportunities for the efficient distribution of MPDATA computation onto available resources of the Intel MIC architecture, as well as Intel CPUs. We discuss preliminary performance results obtained on two hybrid platforms, containing two CPUs and Intel Xeon Phi. The top-of-the-line Intel Xeon Phi 7120P gives the best performance results, and executes MPDATA almost 2 times faster than two Intel Xeon E5-2697v2 CPUs.

  7. Hydrophilic porous magnetic poly(GMA-MBAA-NVP) composite microspheres containing oxirane groups: An efficient carrier for immobilizing penicillin G acylase

    Energy Technology Data Exchange (ETDEWEB)

    Xue, Ping; Su, Weiguang, E-mail: weiguangsu@nxu.edu.cn; Gu, Yaohua; Liu, Haifeng; Wang, Julan

    2015-03-15

    Magnetic hydrophilic polymeric microspheres containing oxirane groups were prepared by inverse suspension polymerization of glycidyl methacrylate (GMA), N, N′-methylene bisacrylamide (MBAA) and N-vinyl pyrrolidone (NVP) in the existence of formamide, which were denoted as magnetic poly(GMA-MBAA-NVP) microspheres. The magnetic poly(GMA-MBAA-NVP) microspheres were characterized by scanning electron microscopy (SEM), FT-IR spectroscopy, X-ray diffraction (XRD), vibrating sample magnetometer (VSM) and so on. The results showed that poly(GMA-MBAA-NVP) microspheres possessed well spherical shape, narrow size distribution, abundant porous structure, reactive oxirane groups and superparamagnetic properties. Formamide used in the present work served as a modifier, a dispersant and a porogen to form final porous polymer microspheres. The penicillin G acylase (PGA) was covalently immobilized onto the magnetic microspheres through the reaction between the amino groups of enzyme and the oxirane groups on the microspheres for producing 6-aminopenicillanic acid (6-APA). The effects of GMA/NVP ratio and crosslink density on the activity of immobilized PGA were investigated. The highest apparent activity, enzyme loading and coupling yield of immobilized PGA were 821 IU/g, 65.3 mg/g and 42.3% respectively when the mass ratio of GMA/NVP was 1:1 and crosslink density was 60%. Compared with the free PGA, immobilized PGA showed a wider range of pH value and reaction temperature. The relative activity and reaction rate of immobilized PGA remained almost constant after 20 recycles. The magnetic poly(GMA-MBAA-NVP) microspheres would be very promising carriers for immobilizing enzymes in industrial application. - Highlights: • The magnetic poly(GMA-MBAA-NVP) microspheres were successfully synthesized. • Formamide served as a modifier, a dispersant and a porogen to form microspheres. • The magnetic microspheres were highly efficient carriers for immobilizing PGA. • Immobilized PGA

  8. EM Modeling of Far-Field Radiation Patterns for Antennas on the GMA-TT UAV

    Science.gov (United States)

    Mackenzie, Anne I.

    2015-01-01

    To optimize communication with the Generic Modular Aircraft T-Tail (GMA-TT) unmanned aerial vehicle (UAV), electromagnetic (EM) simulations have been performed to predict the performance of two antenna types on the aircraft. Simulated far-field radiation patterns tell the amount of power radiated by the antennas and the aircraft together, taking into account blockage by the aircraft as well as radiation by conducting and dielectric portions of the aircraft. With a knowledge of the polarization and distance of the two communicating antennas, e.g. one on the UAV and one on the ground, and the transmitted signal strength, a calculation may be performed to find the strength of the signal travelling from one antenna to the other and to check that the transmitted signal meets the receiver system requirements for the designated range. In order to do this, the antenna frequency and polarization must be known for each antenna, in addition to its design and location. The permittivity, permeability, and geometry of the UAV components must also be known. The full-wave method of moments solution produces the appropriate dBi radiation pattern in which the received signal strength is calculated relative to that of an isotropic radiator.

  9. The Adsorption of Calmoduline via Nicotinamide Immobilized Poly(HEMA-GMA Cryogels

    Directory of Open Access Journals (Sweden)

    Kadir Erol

    2016-12-01

    Full Text Available The separation and purification methods for the isolation of an important biomolecule calmoduline protein is extremely important. Among these methods, the adsorption technique is extremely popular, and the cryogels as adsorbents with the macro porous structure and interconnected flow channels cryogel they have are preferred in this field. In this study, the adsorption of calmoduline via Ca(II immobilized poly (2-hydroxyethyl methacrylate-glycidyl methacrylate, poly (HEMA-GMA, cryogels through changing interaction time, calmoduline initial concentration and temperature conditions. For the characterization of cryogels, the swelling test, Fourier Transform Infrared (FT-IR Spectroscopy, Scanning Electron Microscopy (SEM, surface area (BET, elemental analysis and ICP-OES methods were performed. Nicotinamide molecule was used as Ca (II chelating agent and the adsorption capacity of the cryogels was estimated as 1.812 mg calmoduline / g cryogel. The adsorption models of the adsorption reaction were examined by the Langmuir and Freundlich isotherm models and was determined to be more appropriate for Langmuir isotherm model.

  10. Balancing Contention and Synchronization on the Intel Paragon

    Science.gov (United States)

    Bokhari, Shahid H.; Nicol, David M.

    1996-01-01

    The Intel Paragon is a mesh-connected distributed memory parallel computer. It uses an oblivious and deterministic message routing algorithm: this permits us to develop highly optimized schedules for frequently needed communication patterns. The complete exchange is one such pattern. Several approaches are available for carrying it out on the mesh. We study an algorithm developed by Scott. This algorithm assumes that a communication link can carry one message at a time and that a node can only transmit one message at a time. It requires global synchronization to enforce a schedule of transmissions. Unfortunately global synchronization has substantial overhead on the Paragon. At the same time the powerful interconnection mechanism of this machine permits 2 or 3 messages to share a communication link with minor overhead. It can also overlap multiple message transmission from the same node to some extent. We develop a generalization of Scott's algorithm that executes complete exchange with a prescribed contention. Schedules that incur greater contention require fewer synchronization steps. This permits us to tradeoff contention against synchronization overhead. We describe the performance of this algorithm and compare it with Scott's original algorithm as well as with a naive algorithm that does not take interconnection structure into account. The Bounded contention algorithm is always better than Scott's algorithm and outperforms the naive algorithm for all but the smallest message sizes. The naive algorithm fails to work on meshes larger than 12 x 12. These results show that due consideration of processor interconnect and machine performance parameters is necessary to obtain peak performance from the Paragon and its successor mesh machines.

  11. Multi-Kepler GPU vs. multi-Intel MIC for spin systems simulations

    Science.gov (United States)

    Bernaschi, M.; Bisson, M.; Salvadore, F.

    2014-10-01

    We present and compare the performances of two many-core architectures: the Nvidia Kepler and the Intel MIC both in a single system and in cluster configuration for the simulation of spin systems. As a benchmark we consider the time required to update a single spin of the 3D Heisenberg spin glass model by using the Over-relaxation algorithm. We present data also for a traditional high-end multi-core architecture: the Intel Sandy Bridge. The results show that although on the two Intel architectures it is possible to use basically the same code, the performances of a Intel MIC change dramatically depending on (apparently) minor details. Another issue is that to obtain a reasonable scalability with the Intel Phi coprocessor (Phi is the coprocessor that implements the MIC architecture) in a cluster configuration it is necessary to use the so-called offload mode which reduces the performances of the single system. As to the GPU, the Kepler architecture offers a clear advantage with respect to the previous Fermi architecture maintaining exactly the same source code. Scalability of the multi-GPU implementation remains very good by using the CPU as a communication co-processor of the GPU. All source codes are provided for inspection and for double-checking the results.

  12. Optimizing Performance of Combustion Chemistry Solvers on Intel's Many Integrated Core (MIC) Architectures

    Energy Technology Data Exchange (ETDEWEB)

    Sitaraman, Hariswaran [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Grout, Ray W [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2017-06-09

    This work investigates novel algorithm designs and optimization techniques for restructuring chemistry integrators in zero and multidimensional combustion solvers, which can then be effectively used on the emerging generation of Intel's Many Integrated Core/Xeon Phi processors. These processors offer increased computing performance via large number of lightweight cores at relatively lower clock speeds compared to traditional processors (e.g. Intel Sandybridge/Ivybridge) used in current supercomputers. This style of processor can be productively used for chemistry integrators that form a costly part of computational combustion codes, in spite of their relatively lower clock speeds. Performance commensurate with traditional processors is achieved here through the combination of careful memory layout, exposing multiple levels of fine grain parallelism and through extensive use of vendor supported libraries (Cilk Plus and Math Kernel Libraries). Important optimization techniques for efficient memory usage and vectorization have been identified and quantified. These optimizations resulted in a factor of ~ 3 speed-up using Intel 2013 compiler and ~ 1.5 using Intel 2017 compiler for large chemical mechanisms compared to the unoptimized version on the Intel Xeon Phi. The strategies, especially with respect to memory usage and vectorization, should also be beneficial for general purpose computational fluid dynamics codes.

  13. Hydrophilic porous magnetic poly(GMA-MBAA-NVP) composite microspheres containing oxirane groups: An efficient carrier for immobilizing penicillin G acylase

    Science.gov (United States)

    Xue, Ping; Su, Weiguang; Gu, Yaohua; Liu, Haifeng; Wang, Julan

    2015-03-01

    Magnetic hydrophilic polymeric microspheres containing oxirane groups were prepared by inverse suspension polymerization of glycidyl methacrylate (GMA), N, N‧-methylene bisacrylamide (MBAA) and N-vinyl pyrrolidone (NVP) in the existence of formamide, which were denoted as magnetic poly(GMA-MBAA-NVP) microspheres. The magnetic poly(GMA-MBAA-NVP) microspheres were characterized by scanning electron microscopy (SEM), FT-IR spectroscopy, X-ray diffraction (XRD), vibrating sample magnetometer (VSM) and so on. The results showed that poly(GMA-MBAA-NVP) microspheres possessed well spherical shape, narrow size distribution, abundant porous structure, reactive oxirane groups and superparamagnetic properties. Formamide used in the present work served as a modifier, a dispersant and a porogen to form final porous polymer microspheres. The penicillin G acylase (PGA) was covalently immobilized onto the magnetic microspheres through the reaction between the amino groups of enzyme and the oxirane groups on the microspheres for producing 6-aminopenicillanic acid (6-APA). The effects of GMA/NVP ratio and crosslink density on the activity of immobilized PGA were investigated. The highest apparent activity, enzyme loading and coupling yield of immobilized PGA were 821 IU/g, 65.3 mg/g and 42.3% respectively when the mass ratio of GMA/NVP was 1:1 and crosslink density was 60%. Compared with the free PGA, immobilized PGA showed a wider range of pH value and reaction temperature. The relative activity and reaction rate of immobilized PGA remained almost constant after 20 recycles. The magnetic poly(GMA-MBAA-NVP) microspheres would be very promising carriers for immobilizing enzymes in industrial application.

  14. Intel Xeon Phi accelerated Weather Research and Forecasting (WRF) Goddard microphysics scheme

    Science.gov (United States)

    Mielikainen, J.; Huang, B.; Huang, A. H.-L.

    2014-12-01

    The Weather Research and Forecasting (WRF) model is a numerical weather prediction system designed to serve both atmospheric research and operational forecasting needs. The WRF development is a done in collaboration around the globe. Furthermore, the WRF is used by academic atmospheric scientists, weather forecasters at the operational centers and so on. The WRF contains several physics components. The most time consuming one is the microphysics. One microphysics scheme is the Goddard cloud microphysics scheme. It is a sophisticated cloud microphysics scheme in the Weather Research and Forecasting (WRF) model. The Goddard microphysics scheme is very suitable for massively parallel computation as there are no interactions among horizontal grid points. Compared to the earlier microphysics schemes, the Goddard scheme incorporates a large number of improvements. Thus, we have optimized the Goddard scheme code. In this paper, we present our results of optimizing the Goddard microphysics scheme on Intel Many Integrated Core Architecture (MIC) hardware. The Intel Xeon Phi coprocessor is the first product based on Intel MIC architecture, and it consists of up to 61 cores connected by a high performance on-die bidirectional interconnect. The Intel MIC is capable of executing a full operating system and entire programs rather than just kernels as the GPU does. The MIC coprocessor supports all important Intel development tools. Thus, the development environment is one familiar to a vast number of CPU developers. Although, getting a maximum performance out of MICs will require using some novel optimization techniques. Those optimization techniques are discussed in this paper. The results show that the optimizations improved performance of Goddard microphysics scheme on Xeon Phi 7120P by a factor of 4.7×. In addition, the optimizations reduced the Goddard microphysics scheme's share of the total WRF processing time from 20.0 to 7.5%. Furthermore, the same optimizations

  15. How could the topic patient safety be embedded in the curriculum? A recommendation by the Committee for Patient Safety and Error Management of the GMA.

    Science.gov (United States)

    Kiesewetter, Jan; Drossard, Sabine; Gaupp, Rainer; Baschnegger, Heiko; Kiesewetter, Isabel; Hoffmann, Susanne

    2018-01-01

    The topic of patient safety is of fundamental interest for the health care sector. In view of the realisation of the National Competence-Based Learning Objectives Catalogue for Undergraduate Medical Education (NKLM) this topic now has to be prepared for medical education. For a disciplinary and content-related orientation the GMA Committee developed the Learning Objectives Catalogue Patient Safety for Undergraduate Medical Education (GMA-LZK). To ensure an optimal implementation of the GMA-LZK we recommend a longitudinal embedding into the existing curriculum. This position paper supports the implementation of the GMA-LZK and is aimed at everyone who wants to establish teaching courses on the topic patient safety and embed them in the curriculum. In light of this, we will initially describe the key features for a structured analysis of the current situation. Based on three best-practice-examples, as seen in the faculties of Freiburg, Bonn and Munich, different approaches to the implementation of the GMA-LZK will be illustrated. Lastly, we will outline the methodical requirements regarding the curriculum development as well as the disciplinary and methodical competences that the lecturers will have to hold or develop to fulfil the requirements.

  16. High-performance computing on the Intel Xeon Phi how to fully exploit MIC architectures

    CERN Document Server

    Wang, Endong; Shen, Bo; Zhang, Guangyong; Lu, Xiaowei; Wu, Qing; Wang, Yajuan

    2014-01-01

    The aim of this book is to explain to high-performance computing (HPC) developers how to utilize the Intel® Xeon Phi™ series products efficiently. To that end, it introduces some computing grammar, programming technology and optimization methods for using many-integrated-core (MIC) platforms and also offers tips and tricks for actual use, based on the authors' first-hand optimization experience.The material is organized in three sections. The first section, "Basics of MIC", introduces the fundamentals of MIC architecture and programming, including the specific Intel MIC programming environment

  17. Evaluating the transport layer of the ALFA framework for the Intel® Xeon Phi™ Coprocessor

    Science.gov (United States)

    Santogidis, Aram; Hirstius, Andreas; Lalis, Spyros

    2015-12-01

    The ALFA framework supports the software development of major High Energy Physics experiments. As part of our research effort to optimize the transport layer of ALFA, we focus on profiling its data transfer performance for inter-node communication on the Intel Xeon Phi Coprocessor. In this article we present the collected performance measurements with the related analysis of the results. The optimization opportunities that are discovered, help us to formulate the future plans of enabling high performance data transfer for ALFA on the Intel Xeon Phi architecture.

  18. Implementation of High-Order Multireference Coupled-Cluster Methods on Intel Many Integrated Core Architecture.

    Science.gov (United States)

    Aprà, E; Kowalski, K

    2016-03-08

    In this paper we discuss the implementation of multireference coupled-cluster formalism with singles, doubles, and noniterative triples (MRCCSD(T)), which is capable of taking advantage of the processing power of the Intel Xeon Phi coprocessor. We discuss the integration of two levels of parallelism underlying the MRCCSD(T) implementation with computational kernels designed to offload the computationally intensive parts of the MRCCSD(T) formalism to Intel Xeon Phi coprocessors. Special attention is given to the enhancement of the parallel performance by task reordering that has improved load balancing in the noniterative part of the MRCCSD(T) calculations. We also discuss aspects regarding efficient optimization and vectorization strategies.

  19. Towards Porting a Real-World Seismological Application to the Intel MIC Architecture

    OpenAIRE

    V. Weinberg

    2014-01-01

    This whitepaper aims to discuss first experiences with porting an MPI-based real-world geophysical application to the new Intel Many Integrated Core (MIC) architecture. The selected code SeisSol is an application written in Fortran that can be used to simulate earthquake rupture and radiating seismic wave propagation in complex 3-D heterogeneous materials. The PRACE prototype cluster EURORA at CINECA, Italy, was accessed to analyse the MPI-performance of SeisSol on Intel Xeon Phi on both sing...

  20. Scalability tests of R-GMA based Grid job monitoring system for CMS Monte Carlo data production

    CERN Document Server

    Bonacorsi, D; Field, L; Fisher, S; Grandi, C; Hobson, P R; Kyberd, P; MacEvoy, B; Nebrensky, J J; Tallini, H; Traylen, S

    2004-01-01

    High Energy Physics experiments such as CMS (Compact Muon Solenoid) at the Large Hadron Collider have unprecedented, large-scale data processing computing requirements, with data accumulating at around 1 Gbyte/s. The Grid distributed computing paradigm has been chosen as the solution to provide the requisite computing power. The demanding nature of CMS software and computing requirements, such as the production of large quantities of Monte Carlo simulated data, makes them an ideal test case for the Grid and a major driver for the development of Grid technologies. One important challenge when using the Grid for large-scale data analysis is the ability to monitor the large numbers of jobs that are being executed simultaneously at multiple remote sites. R-GMA is a monitoring and information management service for distributed resources based on the Grid Monitoring Architecture of the Global Grid Forum. In this paper we report on the first measurements of R-GMA as part of a monitoring architecture to be used for b...

  1. Accelerating the Pace of Protein Functional Annotation With Intel Xeon Phi Coprocessors.

    Science.gov (United States)

    Feinstein, Wei P; Moreno, Juana; Jarrell, Mark; Brylinski, Michal

    2015-06-01

    Intel Xeon Phi is a new addition to the family of powerful parallel accelerators. The range of its potential applications in computationally driven research is broad; however, at present, the repository of scientific codes is still relatively limited. In this study, we describe the development and benchmarking of a parallel version of eFindSite, a structural bioinformatics algorithm for the prediction of ligand-binding sites in proteins. Implemented for the Intel Xeon Phi platform, the parallelization of the structure alignment portion of eFindSite using pragma-based OpenMP brings about the desired performance improvements, which scale well with the number of computing cores. Compared to a serial version, the parallel code runs 11.8 and 10.1 times faster on the CPU and the coprocessor, respectively; when both resources are utilized simultaneously, the speedup is 17.6. For example, ligand-binding predictions for 501 benchmarking proteins are completed in 2.1 hours on a single Stampede node equipped with the Intel Xeon Phi card compared to 3.1 hours without the accelerator and 36.8 hours required by a serial version. In addition to the satisfactory parallel performance, porting existing scientific codes to the Intel Xeon Phi architecture is relatively straightforward with a short development time due to the support of common parallel programming models by the coprocessor. The parallel version of eFindSite is freely available to the academic community at www.brylinski.org/efindsite.

  2. Extension of the AMBER molecular dynamics software to Intel's Many Integrated Core (MIC) architecture

    Science.gov (United States)

    Needham, Perri J.; Bhuiyan, Ashraf; Walker, Ross C.

    2016-04-01

    We present an implementation of explicit solvent particle mesh Ewald (PME) classical molecular dynamics (MD) within the PMEMD molecular dynamics engine, that forms part of the AMBER v14 MD software package, that makes use of Intel Xeon Phi coprocessors by offloading portions of the PME direct summation and neighbor list build to the coprocessor. We refer to this implementation as pmemd MIC offload and in this paper present the technical details of the algorithm, including basic models for MPI and OpenMP configuration, and analyze the resultant performance. The algorithm provides the best performance improvement for large systems (>400,000 atoms), achieving a ∼35% performance improvement for satellite tobacco mosaic virus (1,067,095 atoms) when 2 Intel E5-2697 v2 processors (2 ×12 cores, 30M cache, 2.7 GHz) are coupled to an Intel Xeon Phi coprocessor (Model 7120P-1.238/1.333 GHz, 61 cores). The implementation utilizes a two-fold decomposition strategy: spatial decomposition using an MPI library and thread-based decomposition using OpenMP. We also present compiler optimization settings that improve the performance on Intel Xeon processors, while retaining simulation accuracy.

  3. Game-Based Experiential Learning in Online Management Information Systems Classes Using Intel's IT Manager 3

    Science.gov (United States)

    Bliemel, Michael; Ali-Hassan, Hossam

    2014-01-01

    For several years, we used Intel's flash-based game "IT Manager 3: Unseen Forces" as an experiential learning tool, where students had to act as a manager making real-time prioritization decisions about repairing computer problems, training and upgrading systems with better technologies as well as managing increasing numbers of technical…

  4. Newsgroups, Activist Publics, and Corporate Apologia: The Case of Intel and Its Pentium Chip.

    Science.gov (United States)

    Hearit, Keith Michael

    1999-01-01

    Applies J. Grunig's theory of publics to the phenomenon of Internet newsgroups using the case of the flawed Intel Pentium chip. Argues that technology facilitates the rapid movement of publics from the theoretical construct stage to the active stage. Illustrates some of the difficulties companies face in establishing their identity in cyberspace.…

  5. Why K-12 IT Managers and Administrators Are Embracing the Intel-Based Mac

    Science.gov (United States)

    Technology & Learning, 2007

    2007-01-01

    Over the past year, Apple has dramatically increased its share of the school computer marketplace--especially in the category of notebook computers. A recent study conducted by Grunwald Associates and Rockman et al. reports that one of the major reasons for this growth is Apple's introduction of the Intel processor to the entire line of Mac…

  6. Performance tuning Weather Research and Forecasting (WRF) Goddard longwave radiative transfer scheme on Intel Xeon Phi

    Science.gov (United States)

    Mielikainen, Jarno; Huang, Bormin; Huang, Allen H.

    2015-10-01

    Next-generation mesoscale numerical weather prediction system, the Weather Research and Forecasting (WRF) model, is a designed for dual use for forecasting and research. WRF offers multiple physics options that can be combined in any way. One of the physics options is radiance computation. The major source for energy for the earth's climate is solar radiation. Thus, it is imperative to accurately model horizontal and vertical distribution of the heating. Goddard solar radiative transfer model includes the absorption duo to water vapor,ozone, ozygen, carbon dioxide, clouds and aerosols. The model computes the interactions among the absorption and scattering by clouds, aerosols, molecules and surface. Finally, fluxes are integrated over the entire longwave spectrum.In this paper, we present our results of optimizing the Goddard longwave radiative transfer scheme on Intel Many Integrated Core Architecture (MIC) hardware. The Intel Xeon Phi coprocessor is the first product based on Intel MIC architecture, and it consists of up to 61 cores connected by a high performance on-die bidirectional interconnect. The coprocessor supports all important Intel development tools. Thus, the development environment is familiar one to a vast number of CPU developers. Although, getting a maximum performance out of MICs will require using some novel optimization techniques. Those optimization techniques are discusses in this paper. The optimizations improved the performance of the original Goddard longwave radiative transfer scheme on Xeon Phi 7120P by a factor of 2.2x. Furthermore, the same optimizations improved the performance of the Goddard longwave radiative transfer scheme on a dual socket configuration of eight core Intel Xeon E5-2670 CPUs by a factor of 2.1x compared to the original Goddard longwave radiative transfer scheme code.

  7. The differences of saliva pH before and after application of Bis-GMA resin based-pit and fissure sealant

    Directory of Open Access Journals (Sweden)

    Ayub Irmadani Anwar

    2016-06-01

    Full Text Available Pit and fissure sealant applications is one way to prevent caries. One of the effective ingredient as a pit and fissure sealant is a Bis-GMA resin. One of the active components  of  Bis-GMA  resin  is  sodium  fluoride,  which is capable  of releasing fluoride ions to the tooth surface and able to improve the repair and remineralization process through the replacement  of  calcium and phosphate ions found in saliva to increase the pH of saliva. This study was to determine the effect of pit and fissure sealant applications made from Bis-GMA resin to pH of saliva in children aged 6-12 years. The study design is pre and post test with control group design. Saliva samples were derived from 15 pediatric patients has met the criteria. The pH of saliva were taken before and after the application of pit and fissure sealant made from Bis-GMA and measured with pH meter. This study used a non-parametric test, the Wilcoxon Signed Rank test. The results of this study are also supported by the results of statistical tests showed p-: 0.005 (p<0.05 value, which means that there are significant differences in pH of saliva before and after the application of pit and fissure sealant made from Bis-GMA resin.

  8. Investigating the Use of the Intel Xeon Phi for Event Reconstruction

    Science.gov (United States)

    Sherman, Keegan; Gilfoyle, Gerard

    2014-09-01

    The physics goal of Jefferson Lab is to understand how quarks and gluons form nuclei and it is being upgraded to a higher, 12-GeV beam energy. The new CLAS12 detector in Hall B will collect 5-10 terabytes of data per day and will require considerable computing resources. We are investigating tools, such as the Intel Xeon Phi, to speed up the event reconstruction. The Kalman Filter is one of the methods being studied. It is a linear algebra algorithm that estimates the state of a system by combining existing data and predictions of those measurements. The tools required to apply this technique (i.e. matrix multiplication, matrix inversion) are being written using C++ intrinsics for Intel's Xeon Phi Coprocessor, which uses the Many Integrated Cores (MIC) architecture. The Intel MIC is a new high-performance chip that connects to a host machine through the PCIe bus and is built to run highly vectorized and parallelized code making it a well-suited device for applications such as the Kalman Filter. Our tests of the MIC optimized algorithms needed for the filter show significant increases in speed. For example, matrix multiplication of 5x5 matrices on the MIC was able to run up to 69 times faster than the host core. The physics goal of Jefferson Lab is to understand how quarks and gluons form nuclei and it is being upgraded to a higher, 12-GeV beam energy. The new CLAS12 detector in Hall B will collect 5-10 terabytes of data per day and will require considerable computing resources. We are investigating tools, such as the Intel Xeon Phi, to speed up the event reconstruction. The Kalman Filter is one of the methods being studied. It is a linear algebra algorithm that estimates the state of a system by combining existing data and predictions of those measurements. The tools required to apply this technique (i.e. matrix multiplication, matrix inversion) are being written using C++ intrinsics for Intel's Xeon Phi Coprocessor, which uses the Many Integrated Cores (MIC

  9. BisGMA/TEGDMA dental nanocomposites containing glyoxylic acid modified high-aspect ratio hydroxyapatite nanofibers with enhanced dispersion

    Science.gov (United States)

    Chen, Liang; Xu, Changqi; Wang, Yong; Shi, Jian; Yu, Qingsong

    2012-01-01

    The purpose of this research was to investigate the influence of the glyoxylic acid (GA) modification of hydroxyapatite (HAP) nanofibers on their dispersion in bisphenol A glycidyl methacrylate (BisGMA)/triethylene glycol dimethacrylate (TEGDMA) dental composites and also investigate the mechanical properties, water absorption, and water solubility of the resulting dental resins and composites. Scanning/Transmission electron microscopy (STEM) images showed that microsized HAP nanofiber bundles could be effectively broken down to individual HAP nanofibers with an average length of ~15 μm after the surface modification process. Fourier transform infrared spectroscopy (FT-IR), X-ray photoelectron spectroscopy (XPS) and thermal gravimetric analysis (TGA) characterization confirmed glyoxylic acid was chemically grafted on the HAP nanofiber surface, hypothetically by reacting with the amine group on HAP nanofiber surface. The enhanced dispersion of HAP nanofibers in dental matrix led to increased biaxial flexural strength (BFS) compared with the corresponding dental resins and composites filled with untreated HAP nanofibers. In addition, impregnation of small mass fractions of the glyoxylic acid modified HAP nanofibers into the BisGMA/TEGDMA dental resins (5wt%, 10wt%) or composites (2wt%, 3wt%) could also substantially improve the BFS in comparison with the controls(pure resins or dental composites filled with silica particles alone). Larger mass fractions could not further increase the mechanical property or even degrade the BFS values. Water behavior testing results indicated that the addition of glyoxylic acid modified HAP nanofibers resulted in higher water absorption and water solubility values which is not preferred for clinical application. In summary, well dispersed HAP nanofibers and their dental composites with enhanced mechanical property have been successfully fabricated but the water absorption and water solubility of such dental composites need to be

  10. BisGMA/TEGDMA dental nanocomposites containing glyoxylic acid-modified high-aspect ratio hydroxyapatite nanofibers with enhanced dispersion

    International Nuclear Information System (INIS)

    Chen Liang; Yu Qingsong; Li Hao; Xu Changqi; Wang Yong; Shi Jian

    2012-01-01

    The purpose of this research was to investigate the influence of the glyoxylic acid (GA) modification of hydroxyapatite (HAP) nanofibers on their dispersion in bisphenol A glycidyl methacrylate (BisGMA)/triethylene glycol dimethacrylate (TEGDMA) dental composites and also to investigate the mechanical properties, water absorption and water solubility of the resulting dental resins and composites. Scanning/transmission electron microscopy images showed that microsized HAP nanofiber bundles could be effectively broken down into individual HAP nanofibers with an average length of ∼15 µm after the surface modification process. Fourier transform infrared spectroscopy, x-ray photoelectron spectroscopy and thermal gravimetric analysis characterization confirmed that GA was chemically grafted on the HAP nanofiber surface, hypothetically by reacting with the amine group on the HAP nanofiber surface. The enhanced dispersion of HAP nanofibers in the dental matrix led to increased biaxial flexural strength (BFS) compared with the corresponding dental resins and composites filled with untreated HAP nanofibers. In addition, impregnation of small mass fractions of the GA-modified HAP nanofibers into the BisGMA/TEGDMA dental resins (5 wt%, 10 wt%) or composites (2 wt%, 3 wt%) could also substantially improve the BFS in comparison with the controls (pure resins or dental composites filled with silica particles alone). Larger mass fractions could not increase the mechanical property further or even degraded the BFS values. Water behavior testing results indicated that the addition of the GA-modified HAP nanofibers resulted in higher water absorption and water solubility values, which are not preferred for clinical application. In summary, well-dispersed HAP nanofibers and their dental composites with enhanced mechanical properties have been successfully fabricated, but the water absorption and water solubility of such dental composites need to be further improved. (paper)

  11. Blocked All-Pairs Shortest Paths Algorithm on Intel Xeon Phi KNL Processor: A Case Study

    OpenAIRE

    Rucci, Enzo; De Giusti, Armando Eduardo; Naiouf, Marcelo

    2017-01-01

    Manycores are consolidating in HPC community as a way of improving performance while keeping power efficiency. Knights Landing is the recently released second generation of Intel Xeon Phi architec- ture.While optimizing applications on CPUs, GPUs and first Xeon Phi’s has been largely studied in the last years, the new features in Knights Landing processors require the revision of programming and optimization techniques for these devices. In this work, we selected the Floyd-Warshall algorithm ...

  12. Benchmarking Data Analysis and Machine Learning Applications on the Intel KNL Many-Core Processor

    OpenAIRE

    Byun, Chansup; Kepner, Jeremy; Arcand, William; Bestor, David; Bergeron, Bill; Gadepally, Vijay; Houle, Michael; Hubbell, Matthew; Jones, Michael; Klein, Anna; Michaleas, Peter; Milechin, Lauren; Mullen, Julie; Prout, Andrew; Rosa, Antonio

    2017-01-01

    Knights Landing (KNL) is the code name for the second-generation Intel Xeon Phi product family. KNL has generated significant interest in the data analysis and machine learning communities because its new many-core architecture targets both of these workloads. The KNL many-core vector processor design enables it to exploit much higher levels of parallelism. At the Lincoln Laboratory Supercomputing Center (LLSC), the majority of users are running data analysis applications such as MATLAB and O...

  13. Accelerating the Global Nested Air Quality Prediction Modeling System (GNAQPMS) model on Intel Xeon Phi processors

    OpenAIRE

    Wang, Hui; Chen, Huansheng; Wu, Qizhong; Lin, Junming; Chen, Xueshun; Xie, Xinwei; Wang, Rongrong; Tang, Xiao; Wang, Zifa

    2017-01-01

    The GNAQPMS model is the global version of the Nested Air Quality Prediction Modelling System (NAQPMS), which is a multi-scale chemical transport model used for air quality forecast and atmospheric environmental research. In this study, we present our work of porting and optimizing the GNAQPMS model on the second generation Intel Xeon Phi processor codename “Knights Landing” (KNL). Compared with the first generation Xeon Phi coprocessor, KNL introduced many new hardware features such as a boo...

  14. Applying the roofline performance model to the intel xeon phi knights landing processor

    OpenAIRE

    Doerfler, D; Deslippe, J; Williams, S; Oliker, L; Cook, B; Kurth, T; Lobet, M; Malas, T; Vay, JL; Vincenti, H

    2016-01-01

    � Springer International Publishing AG 2016. The Roofline Performance Model is a visually intuitive method used to bound the sustained peak floating-point performance of any given arithmetic kernel on any given processor architecture. In the Roofline, performance is nominally measured in floating-point operations per second as a function of arithmetic intensity (operations per byte of data). In this study we determine the Roofline for the Intel Knights Landing (KNL) processor, determining t...

  15. Efficient irregular wavefront propagation algorithms on Intel® Xeon Phi™

    OpenAIRE

    Gomes, Jeremias M.; Teodoro, George; de Melo, Alba; Kong, Jun; Kurc, Tahsin; Saltz, Joel H.

    2015-01-01

    We investigate the execution of the Irregular Wavefront Propagation Pattern (IWPP), a fundamental computing structure used in several image analysis operations, on the Intel® Xeon Phi™ co-processor. An efficient implementation of IWPP on the Xeon Phi is a challenging problem because of IWPP’s irregularity and the use of atomic instructions in the original IWPP algorithm to resolve race conditions. On the Xeon Phi, the use of SIMD and vectorization instructions is critical to attain high perfo...

  16. Performance Engineering for a Medical Imaging Application on the Intel Xeon Phi Accelerator

    OpenAIRE

    Hofmann, Johannes; Treibig, Jan; Hager, Georg; Wellein, Gerhard

    2013-01-01

    We examine the Xeon Phi, which is based on Intel's Many Integrated Cores architecture, for its suitability to run the FDK algorithm--the most commonly used algorithm to perform the 3D image reconstruction in cone-beam computed tomography. We study the challenges of efficiently parallelizing the application and means to enable sensible data sharing between threads despite the lack of a shared last level cache. Apart from parallelization, SIMD vectorization is critical for good performance on t...

  17. DBPQL: A view-oriented query language for the Intel Data Base Processor

    Science.gov (United States)

    Fishwick, P. A.

    1983-01-01

    An interactive query language (BDPQL) for the Intel Data Base Processor (DBP) is defined. DBPQL includes a parser generator package which permits the analyst to easily create and manipulate the query statement syntax and semantics. The prototype language, DBPQL, includes trace and performance commands to aid the analyst when implementing new commands and analyzing the execution characteristics of the DBP. The DBPQL grammar file and associated key procedures are included as an appendix to this report.

  18. Autonomous controller (JCAM 10) for CAMAC crate with 8080 (INTEL) microprocessor

    International Nuclear Information System (INIS)

    Gallice, P.; Mathis, M.

    1975-01-01

    The CAMAC crate autonomous controller JCAM-10 is designed around an INTEL 8080 microprocessor in association with a 5K RAM and 4K REPROM memory. The concept of the module is described, in which data transfers between CAMAC modules and the memory are optimised from software point of view as well as from execution time. In fact, the JCAM-10 is a microcomputer with a set of 1000 peripheral units represented by the CAMAC modules commercially available

  19. Practical Implementation of Lattice QCD Simulation on Intel Xeon Phi Knights Landing

    OpenAIRE

    Kanamori, Issaku; Matsufuru, Hideo

    2017-01-01

    We investigate implementation of lattice Quantum Chromodynamics (QCD) code on the Intel Xeon Phi Knights Landing (KNL). The most time consuming part of the numerical simulations of lattice QCD is a solver of linear equation for a large sparse matrix that represents the strong interaction among quarks. To establish widely applicable prescriptions, we examine rather general methods for the SIMD architecture of KNL, such as using intrinsics and manual prefetching, to the matrix multiplication an...

  20. Acceleration of Blender Cycles Path-Tracing Engine Using Intel Many Integrated Core Architecture

    OpenAIRE

    Jaroš , Milan; Říha , Lubomír; Strakoš , Petr; Karásek , Tomáš; Vašatová , Alena; Jarošová , Marta; Kozubek , Tomáš

    2015-01-01

    Part 2: Algorithms; International audience; This paper describes the acceleration of the most computationally intensive kernels of the Blender rendering engine, Blender Cycles, using Intel Many Integrated Core architecture (MIC). The proposed parallelization, which uses OpenMP technology, also improves the performance of the rendering engine when running on multi-core CPUs and multi-socket servers. Although the GPU acceleration is already implemented in Cycles, its functionality is limited. O...

  1. Real-time data acquisition and feedback control using Linux Intel computers

    International Nuclear Information System (INIS)

    Penaflor, B.G.; Ferron, J.R.; Piglowski, D.A.; Johnson, R.D.; Walker, M.L.

    2006-01-01

    This paper describes the experiences of the DIII-D programming staff in adapting Linux based Intel computing hardware for use in real-time data acquisition and feedback control systems. Due to the highly dynamic and unstable nature of magnetically confined plasmas in tokamak fusion experiments, real-time data acquisition and feedback control systems are in routine use with all major tokamaks. At DIII-D, plasmas are created and sustained using a real-time application known as the digital plasma control system (PCS). During each experiment, the PCS periodically samples data from hundreds of diagnostic signals and provides these data to control algorithms implemented in software. These algorithms compute the necessary commands to send to various actuators that affect plasma performance. The PCS consists of a group of rack mounted Intel Xeon computer systems running an in-house customized version of the Linux operating system tailored specifically to meet the real-time performance needs of the plasma experiments. This paper provides a more detailed description of the real-time computing hardware and custom developed software, including recent work to utilize dual Intel Xeon equipped computers within the PCS

  2. Implementation of an Agent-Based Parallel Tissue Modelling Framework for the Intel MIC Architecture

    Directory of Open Access Journals (Sweden)

    Maciej Cytowski

    2017-01-01

    Full Text Available Timothy is a novel large scale modelling framework that allows simulating of biological processes involving different cellular colonies growing and interacting with variable environment. Timothy was designed for execution on massively parallel High Performance Computing (HPC systems. The high parallel scalability of the implementation allows for simulations of up to 109 individual cells (i.e., simulations at tissue spatial scales of up to 1 cm3 in size. With the recent advancements of the Timothy model, it has become critical to ensure appropriate performance level on emerging HPC architectures. For instance, the introduction of blood vessels supplying nutrients to the tissue is a very important step towards realistic simulations of complex biological processes, but it greatly increased the computational complexity of the model. In this paper, we describe the process of modernization of the application in order to achieve high computational performance on HPC hybrid systems based on modern Intel® MIC architecture. Experimental results on the Intel Xeon Phi™ coprocessor x100 and the Intel Xeon Phi processor x200 are presented.

  3. Experience with Intel's many integrated core architecture in ATLAS software

    International Nuclear Information System (INIS)

    Fleischmann, S; Neumann, M; Kama, S; Lavrijsen, W; Vitillo, R

    2014-01-01

    Intel recently released the first commercial boards of its Many Integrated Core (MIC) Architecture. MIC is Intel's solution for the domain of throughput computing, currently dominated by general purpose programming on graphics processors (GPGPU). MIC allows the use of the more familiar x86 programming model and supports standard technologies such as OpenMP, MPI, and Intel's Threading Building Blocks (TBB). This should make it possible to develop for both throughput and latency devices using a single code base. In ATLAS Software, track reconstruction has been shown to be a good candidate for throughput computing on GPGPU devices. In addition, the newly proposed offline parallel event-processing framework, GaudiHive, uses TBB for task scheduling. The MIC is thus, in principle, a good fit for this domain. In this paper, we report our experiences of porting to and optimizing ATLAS tracking algorithms for the MIC, comparing the programmability and relative cost/performance of the MIC against those of current GPGPUs and latency-optimized CPUs.

  4. Scaling deep learning workloads: NVIDIA DGX-1/Pascal and Intel Knights Landing

    Energy Technology Data Exchange (ETDEWEB)

    Gawande, Nitin A.; Landwehr, Joshua B.; Daily, Jeffrey A.; Tallent, Nathan R.; Vishnu, Abhinav; Kerbyson, Darren J.

    2017-08-24

    Deep Learning (DL) algorithms have become ubiquitous in data analytics. As a result, major computing vendors --- including NVIDIA, Intel, AMD, and IBM --- have architectural road-maps influenced by DL workloads. Furthermore, several vendors have recently advertised new computing products as accelerating large DL workloads. Unfortunately, it is difficult for data scientists to quantify the potential of these different products. This paper provides a performance and power analysis of important DL workloads on two major parallel architectures: NVIDIA DGX-1 (eight Pascal P100 GPUs interconnected with NVLink) and Intel Knights Landing (KNL) CPUs interconnected with Intel Omni-Path or Cray Aries. Our evaluation consists of a cross section of convolutional neural net workloads: CifarNet, AlexNet, GoogLeNet, and ResNet50 topologies using the Cifar10 and ImageNet datasets. The workloads are vendor-optimized for each architecture. Our analysis indicates that although GPUs provide the highest overall performance, the gap can close for some convolutional networks; and the KNL can be competitive in performance/watt. We find that NVLink facilitates scaling efficiency on GPUs. However, its importance is heavily dependent on neural network architecture. Furthermore, for weak-scaling --- sometimes encouraged by restricted GPU memory --- NVLink is less important.

  5. Scaling Deep Learning Workloads: NVIDIA DGX-1/Pascal and Intel Knights Landing

    Energy Technology Data Exchange (ETDEWEB)

    Gawande, Nitin A.; Landwehr, Joshua B.; Daily, Jeffrey A.; Tallent, Nathan R.; Vishnu, Abhinav; Kerbyson, Darren J.

    2017-07-03

    Deep Learning (DL) algorithms have become ubiquitous in data analytics. As a result, major computing vendors --- including NVIDIA, Intel, AMD and IBM --- have architectural road-maps influenced by DL workloads. Furthermore, several vendors have recently advertised new computing products as accelerating DL workloads. Unfortunately, it is difficult for data scientists to quantify the potential of these different products. This paper provides a performance and power analysis of important DL workloads on two major parallel architectures: NVIDIA DGX-1 (eight Pascal P100 GPUs interconnected with NVLink) and Intel Knights Landing (KNL) CPUs interconnected with Intel Omni-Path. Our evaluation consists of a cross section of convolutional neural net workloads: CifarNet, CaffeNet, AlexNet and GoogleNet topologies using the Cifar10 and ImageNet datasets. The workloads are vendor optimized for each architecture. GPUs provide the highest overall raw performance. Our analysis indicates that although GPUs provide the highest overall performance, the gap can close for some convolutional networks; and KNL can be competitive when considering performance/watt. Furthermore, NVLink is critical to GPU scaling.

  6. Influence of shielding gas on the mechanical and metallurgical properties of DP-GMA-welded 5083-H321 aluminum alloy

    Science.gov (United States)

    Koushki, Amin Reza; Goodarzi, Massoud; Paidar, Moslem

    2016-12-01

    In the present research, 6-mm-thick 5083-H321 aluminum alloy was joined by the double-pulsed gas metal arc welding (DP-GMAW) process. The objective was to investigate the influence of the shielding gas composition on the microstructure and properties of GMA welds. A macrostructural study indicated that the addition of nitrogen and oxygen to the argon shielding gas resulted in better weld penetration. Furthermore, the tensile strength and bending strength of the welds were improved when oxygen and nitrogen (at concentrations as high as approximately 0.1vol%) were added to the shielding gas; however, these properties were adversely affected when the oxygen and nitrogen contents were increased further. This behavior was attributed to the formation of excessive brown and black oxide films on the bead surface, the formation of intermetallic compounds in the weld metal, and the formation of thicker oxide layers on the bead surface with increasing nitrogen and oxygen contents in the argon-based shielding gas. Analysis by energy-dispersive X-ray spectroscopy revealed that most of these compounds are nitrides or oxides.

  7. NaF-loaded core-shell PAN-PMMA nanofibers as reinforcements for Bis-GMA/TEGDMA restorative resins.

    Science.gov (United States)

    Cheng, Liyuan; Zhou, Xuegang; Zhong, Hong; Deng, Xuliang; Cai, Qing; Yang, Xiaoping

    2014-01-01

    A kind of core-shell nanofibers containing sodium fluoride (NaF) was produced and used as reinforcing materials for dimethacrylate-based dental restorative resins in this study. The core-shell nanofibers were prepared by coaxial-electrospinning with polyacrylonitrile (PAN) and poly(methyl methacrylate) (PMMA) solutions as core and shell fluids, respectively. The produced PAN-PMMA nanofibers varied in fiber diameter and the thickness of PMMA shell depending on electrospinning parameters. NaF-loaded nanofibers were obtained by incorporating NaF nanocrystals into the core fluid at two loadings (0.8 or 1.0wt.%). Embedment of NaF nanocrystals into the PAN core did not damage the core-shell structure. The addition of PAN-PMMA nanofibers into Bis-GMA/TEGDMA clearly showed the reinforcement due to the good interfacial adhesion between fibers and resin. The flexural strength (Fs) and flexural modulus (Ey) of the composites decreased slightly as the thickness of PMMA shell increasing. Sustained fluoride releases with minor initial burst release were achieved from NaF-loaded core-shell nanofibers and the corresponding composites, which was quite different from the case of embedding NaF nanocrystals into the dental resin directly. The study demonstrated that NaF-loaded PAN-PMMA core-shell nanofibers were not only able to improve the mechanical properties of restorative resin, but also able to provide sustained fluoride release to help in preventing secondary caries. © 2013.

  8. A high-throughput readout architecture based on PCI-Express Gen3 and DirectGMA technology

    International Nuclear Information System (INIS)

    Rota, L.; Vogelgesang, M.; Perez, L.E. Ardila; Caselle, M.; Chilingaryan, S.; Dritschler, T.; Zilio, N.; Kopmann, A.; Balzer, M.; Weber, M.

    2016-01-01

    Modern physics experiments produce multi-GB/s data rates. Fast data links and high performance computing stages are required for continuous data acquisition and processing. Because of their intrinsic parallelism and computational power, GPUs emerged as an ideal solution to process this data in high performance computing applications. In this paper we present a high-throughput platform based on direct FPGA-GPU communication. The architecture consists of a Direct Memory Access (DMA) engine compatible with the Xilinx PCI-Express core, a Linux driver for register access, and high- level software to manage direct memory transfers using AMD's DirectGMA technology. Measurements with a Gen3 x8 link show a throughput of 6.4 GB/s for transfers to GPU memory and 6.6 GB/s to system memory. We also assess the possibility of using the architecture in low latency systems: preliminary measurements show a round-trip latency as low as 1 μs for data transfers to system memory, while the additional latency introduced by OpenCL scheduling is the current limitation for GPU based systems. Our implementation is suitable for real-time DAQ system applications ranging from photon science and medical imaging to High Energy Physics (HEP) systems

  9. Comparative Study of Structure-Property Relationships in Polymer Networks Based on Bis-GMA, TEGDMA and Various Urethane-Dimethacrylates

    Directory of Open Access Journals (Sweden)

    Izabela Barszczewska-Rybarek

    2015-03-01

    Full Text Available The effect of various dimethacrylates on the structure and properties of homo- and copolymer networks was studied. The 2,2-bis-[4-(2-hydroxy-3- methacryloyloxypropoxyphenyl]-propane (Bis-GMA, triethylene glycol dimethacrylate (TEGDMA and 1,6-bis-(methacryloyloxy-2-ethoxycarbonylamino-2,4,4-trimethylhexane (HEMA/TMDI, all popular in dentistry, as well as five urethane-dimethacrylate (UDMA alternatives of HEMA/TMDI were used as monomers. UDMAs were obtained from mono-, di- and tri(ethylene glycol monomethacrylates and various commercial diisocyanates. The chemical structure, degree of conversion (DC and scanning electron microscopy (SEM fracture morphology were related to the mechanical properties of the polymers: flexural strength and modulus, hardness, as well as impact strength. Impact resistance was widely discussed, being lower than expected in the case of poly(UDMAs. It was caused by the heterogeneous morphology of these polymers and only moderate strength of hydrogen bonds between urethane groups, which was not high enough to withstand high impact energy. Bis-GMA, despite having the highest polymer morphological heterogeneity, ensured fair impact resistance, due to having the strongest hydrogen bonds between hydroxyl groups. The TEGDMA homopolymer, despite being heterogeneous, produced the smoothest morphology, which resulted in the lowest brittleness. The UDMA monomer, having diethylene glycol monomethacrylate wings and the isophorone core, could be the most suitable HEMA/TMDI alternative. Its copolymer with Bis-GMA and TEGDMA had improved DC as well as all the mechanical properties.

  10. The future of graduate medical education in Germany - position paper of the Committee on Graduate Medical Education of the Society for Medical Education (GMA).

    Science.gov (United States)

    David, Dagmar M; Euteneier, Alexander; Fischer, Martin R; Hahn, Eckhart G; Johannink, Jonas; Kulike, Katharina; Lauch, Robert; Lindhorst, Elmar; Noll-Hussong, Michael; Pinilla, Severin; Weih, Markus; Wennekes, Vanessa

    2013-01-01

    The German graduate medical education system is going through an important phase of changes. Besides the ongoing reform of the national guidelines for graduate medical education (Musterweiterbildungsordnung), other factors like societal and demographic changes, health and research policy reforms also play a central role for the future and competitiveness of graduate medical education. With this position paper, the committee on graduate medical education of the Society for Medical Education (GMA) would like to point out some central questions for this process and support the current discourse. As an interprofessional and interdisciplinary scientific society, the GMA has the resources to contribute in a meaningful way to an evidence-based and future-oriented graduate medical education strategy. In this position paper, we use four key questions with regards to educational goals, quality assurance, teaching competence and policy requirements to address the core issues for the future of graduate medical education in Germany. The GMA sees its task in contributing to the necessary reform processes as the only German speaking scientific society in the field of medical education.

  11. Evaluation of vectorization potential of Graph500 on Intel's Xeon Phi

    OpenAIRE

    Stanic, Milan; Palomar, Oscar; Ratkovic, Ivan; Duric, Milovan; Unsal, Osman; Cristal, Adrian; Valero, Mateo

    2014-01-01

    Graph500 is a data intensive application for high performance computing and it is an increasingly important workload because graphs are a core part of most analytic applications. So far there is no work that examines if Graph500 is suitable for vectorization mostly due a lack of vector memory instructions for irregular memory accesses. The Xeon Phi is a massively parallel processor recently released by Intel with new features such as a wide 512-bit vector unit and vector scatter/gather instru...

  12. Performance Analysis of an Astrophysical Simulation Code on the Intel Xeon Phi Architecture

    OpenAIRE

    Noormofidi, Vahid; Atlas, Susan R.; Duan, Huaiyu

    2015-01-01

    We have developed the astrophysical simulation code XFLAT to study neutrino oscillations in supernovae. XFLAT is designed to utilize multiple levels of parallelism through MPI, OpenMP, and SIMD instructions (vectorization). It can run on both CPU and Xeon Phi co-processors based on the Intel Many Integrated Core Architecture (MIC). We analyze the performance of XFLAT on configurations with CPU only, Xeon Phi only and both CPU and Xeon Phi. We also investigate the impact of I/O and the multi-n...

  13. Optimizing the MapReduce Framework on Intel Xeon Phi Coprocessor

    OpenAIRE

    Lu, Mian; Zhang, Lei; Huynh, Huynh Phung; Ong, Zhongliang; Liang, Yun; He, Bingsheng; Goh, Rick Siow Mong; Huynh, Richard

    2013-01-01

    With the ease-of-programming, flexibility and yet efficiency, MapReduce has become one of the most popular frameworks for building big-data applications. MapReduce was originally designed for distributed-computing, and has been extended to various architectures, e,g, multi-core CPUs, GPUs and FPGAs. In this work, we focus on optimizing the MapReduce framework on Xeon Phi, which is the latest product released by Intel based on the Many Integrated Core Architecture. To the best of our knowledge...

  14. Mashup d'aplicacions basat en un buscador intel·ligent

    OpenAIRE

    Sancho Piqueras, Javier

    2010-01-01

    Mashup de funcionalitats, basat en un cercador intel·ligent, en aquest cas pensat per a cursos, carreres màsters, etc. La finalitat és adjuntar diverses aplicacions amb l'únic propòsit que en aquest cas és un buscador però que també ens permet utilitzar eines per a la connectivitat mitjançant web Services, o xarxes socials. Mashup de funcionalidades, basado en un buscador inteligente, en este caso pensado para cursos, carreras másters, etc. La finalidad es juntar diversas aplicaciones con ...

  15. Profiling CPU-bound workloads on Intel Haswell-EP platforms

    CERN Document Server

    Guerri, Marco; Cristovao, Cordeiro; CERN. Geneva. IT Department

    2017-01-01

    With the increasing adoption of public and private cloud resources to support the demands in terms of computing capacity of the WLCG, the HEP community has begun studying several benchmarking applications aimed at continuously assessing the performance of virtual machines procured from commercial providers. In order to characterise the behaviour of these benchmarks, in-depth profiling activities have been carried out. In this document we outline our experience in profiling one specific application, the ATLAS Kit Validation, in an attempt to explain an unexpected distribution in the performance samples obtained on systems based on Intel Haswell-EP processors.

  16. A new shared-memory programming paradigm for molecular dynamics simulations on the Intel Paragon

    International Nuclear Information System (INIS)

    D'Azevedo, E.F.; Romine, C.H.

    1994-12-01

    This report describes the use of shared memory emulation with DOLIB (Distributed Object Library) to simplify parallel programming on the Intel Paragon. A molecular dynamics application is used as an example to illustrate the use of the DOLIB shared memory library. SOTON-PAR, a parallel molecular dynamics code with explicit message-passing using a Lennard-Jones 6-12 potential, is rewritten using DOLIB primitives. The resulting code has no explicit message primitives and resembles a serial code. The new code can perform dynamic load balancing and achieves better performance than the original parallel code with explicit message-passing

  17. Optimizing the updated Goddard shortwave radiation Weather Research and Forecasting (WRF) scheme for Intel Many Integrated Core (MIC) architecture

    Science.gov (United States)

    Mielikainen, Jarno; Huang, Bormin; Huang, Allen H.-L.

    2015-05-01

    Intel Many Integrated Core (MIC) ushers in a new era of supercomputing speed, performance, and compatibility. It allows the developers to run code at trillions of calculations per second using the familiar programming model. In this paper, we present our results of optimizing the updated Goddard shortwave radiation Weather Research and Forecasting (WRF) scheme on Intel Many Integrated Core Architecture (MIC) hardware. The Intel Xeon Phi coprocessor is the first product based on Intel MIC architecture, and it consists of up to 61 cores connected by a high performance on-die bidirectional interconnect. The co-processor supports all important Intel development tools. Thus, the development environment is familiar one to a vast number of CPU developers. Although, getting a maximum performance out of Xeon Phi will require using some novel optimization techniques. Those optimization techniques are discusses in this paper. The results show that the optimizations improved performance of the original code on Xeon Phi 7120P by a factor of 1.3x.

  18. Roofline Analysis in the Intel® Advisor to Deliver Optimized Performance for applications on Intel® Xeon Phi™ Processor

    Energy Technology Data Exchange (ETDEWEB)

    Koskela, Tuomas S.; Lobet, Mathieu; Deslippe, Jack; Matveev, Zakhar

    2017-05-23

    In this session we show, in two case studies, how the roofline feature of Intel Advisor has been utilized to optimize the performance of kernels of the XGC1 and PICSAR codes in preparation for Intel Knights Landing architecture. The impact of the implemented optimizations and the benefits of using the automatic roofline feature of Intel Advisor to study performance of large applications will be presented. This demonstrates an effective optimization strategy that has enabled these science applications to achieve up to 4.6 times speed-up and prepare for future exascale architectures. # Goal/Relevance of Session The roofline model [1,2] is a powerful tool for analyzing the performance of applications with respect to the theoretical peak achievable on a given computer architecture. It allows one to graphically represent the performance of an application in terms of operational intensity, i.e. the ratio of flops performed and bytes moved from memory in order to guide optimization efforts. Given the scale and complexity of modern science applications, it can often be a tedious task for the user to perform the analysis on the level of functions or loops to identify where performance gains can be made. With new Intel tools, it is now possible to automate this task, as well as base the estimates of peak performance on measurements rather than vendor specifications. The goal of this session is to demonstrate how the roofline feature of Intel Advisor can be used to balance memory vs. computation related optimization efforts and effectively identify performance bottlenecks. A series of typical optimization techniques: cache blocking, structure refactoring, data alignment, and vectorization illustrated by the kernel cases will be addressed. # Description of the codes ## XGC1 The XGC1 code [3] is a magnetic fusion Particle-In-Cell code that uses an unstructured mesh for its Poisson solver that allows it to accurately resolve the edge plasma of a magnetic fusion device. After

  19. Application of Intel Many Integrated Core (MIC) accelerators to the Pleim-Xiu land surface scheme

    Science.gov (United States)

    Huang, Melin; Huang, Bormin; Huang, Allen H.

    2015-10-01

    The land-surface model (LSM) is one physics process in the weather research and forecast (WRF) model. The LSM includes atmospheric information from the surface layer scheme, radiative forcing from the radiation scheme, and precipitation forcing from the microphysics and convective schemes, together with internal information on the land's state variables and land-surface properties. The LSM is to provide heat and moisture fluxes over land points and sea-ice points. The Pleim-Xiu (PX) scheme is one LSM. The PX LSM features three pathways for moisture fluxes: evapotranspiration, soil evaporation, and evaporation from wet canopies. To accelerate the computation process of this scheme, we employ Intel Xeon Phi Many Integrated Core (MIC) Architecture as it is a multiprocessor computer structure with merits of efficient parallelization and vectorization essentials. Our results show that the MIC-based optimization of this scheme running on Xeon Phi coprocessor 7120P improves the performance by 2.3x and 11.7x as compared to the original code respectively running on one CPU socket (eight cores) and on one CPU core with Intel Xeon E5-2670.

  20. Optimizing the Betts-Miller-Janjic cumulus parameterization with Intel Many Integrated Core (MIC) architecture

    Science.gov (United States)

    Huang, Melin; Huang, Bormin; Huang, Allen H.-L.

    2015-10-01

    The schemes of cumulus parameterization are responsible for the sub-grid-scale effects of convective and/or shallow clouds, and intended to represent vertical fluxes due to unresolved updrafts and downdrafts and compensating motion outside the clouds. Some schemes additionally provide cloud and precipitation field tendencies in the convective column, and momentum tendencies due to convective transport of momentum. The schemes all provide the convective component of surface rainfall. Betts-Miller-Janjic (BMJ) is one scheme to fulfill such purposes in the weather research and forecast (WRF) model. National Centers for Environmental Prediction (NCEP) has tried to optimize the BMJ scheme for operational application. As there are no interactions among horizontal grid points, this scheme is very suitable for parallel computation. With the advantage of Intel Xeon Phi Many Integrated Core (MIC) architecture, efficient parallelization and vectorization essentials, it allows us to optimize the BMJ scheme. If compared to the original code respectively running on one CPU socket (eight cores) and on one CPU core with Intel Xeon E5-2670, the MIC-based optimization of this scheme running on Xeon Phi coprocessor 7120P improves the performance by 2.4x and 17.0x, respectively.

  1. Optimizing zonal advection of the Advanced Research WRF (ARW) dynamics for Intel MIC

    Science.gov (United States)

    Mielikainen, Jarno; Huang, Bormin; Huang, Allen H.

    2014-10-01

    The Weather Research and Forecast (WRF) model is the most widely used community weather forecast and research model in the world. There are two distinct varieties of WRF. The Advanced Research WRF (ARW) is an experimental, advanced research version featuring very high resolution. The WRF Nonhydrostatic Mesoscale Model (WRF-NMM) has been designed for forecasting operations. WRF consists of dynamics code and several physics modules. The WRF-ARW core is based on an Eulerian solver for the fully compressible nonhydrostatic equations. In the paper, we will use Intel Intel Many Integrated Core (MIC) architecture to substantially increase the performance of a zonal advection subroutine for optimization. It is of the most time consuming routines in the ARW dynamics core. Advection advances the explicit perturbation horizontal momentum equations by adding in the large-timestep tendency along with the small timestep pressure gradient tendency. We will describe the challenges we met during the development of a high-speed dynamics code subroutine for MIC architecture. Furthermore, lessons learned from the code optimization process will be discussed. The results show that the optimizations improved performance of the original code on Xeon Phi 5110P by a factor of 2.4x.

  2. Implementation of a 3-D nonlinear MHD [magnetohydrodynamics] calculation on the Intel hypercube

    International Nuclear Information System (INIS)

    Lynch, V.E.; Carreras, B.A.; Drake, J.B.; Hicks, H.R.; Lawkins, W.F.

    1987-01-01

    The optimization of numerical schemes and increasing computer capabilities in the last ten years have improved the efficiency of 3-D nonlinear resistive MHD calculations by about two to three orders of magnitude. However, we are still very limited in performing these types of calculations. Hypercubes have a large number of processors with only local memory and bidirectional links among neighbors. The Intel Hypercube at Oak Ridge has 64 processors with 0.5 megabytes of memory per processor. The multiplicity of processors opens new possibilities for the treatment of such computations. The constraint on time and resources favored the approach of using the existing RSF code which solves as an initial value problem the reduced set of MHD equations for a periodic cylindrical geometry. This code includes minimal physics and geometry, but contains the basic three dimensionality and nonlinear structure of the equations. The code solves the reduced set of MHD equations by Fourier expansion in two angular coordinates and finite differences in the radial one. Due to the continuing interest in these calculations and the likelihood that future supercomputers will take greater advantage of parallelism, the present study was initiated by the ORNL Exploratory Studies Committee and funded entirely by Laboratory Discretionary Funds. The objectives of the study were: to ascertain the suitability of MHD calculation for parallel computation, to design and implement a parallel algorithm to perform the computations, and to evaluate the hypercube, and in particular, ORNL's Intel iPSC, for use in MHD computations

  3. 3-D electromagnetic plasma particle simulations on the Intel Delta parallel computer

    International Nuclear Information System (INIS)

    Wang, J.; Liewer, P.C.

    1994-01-01

    A three-dimensional electromagnetic PIC code has been developed on the 512 node Intel Touchstone Delta MIMD parallel computer. This code is based on the General Concurrent PIC algorithm which uses a domain decomposition to divide the computation among the processors. The 3D simulation domain can be partitioned into 1-, 2-, or 3-dimensional sub-domains. Particles must be exchanged between processors as they move among the subdomains. The Intel Delta allows one to use this code for very-large-scale simulations (i.e. over 10 8 particles and 10 6 grid cells). The parallel efficiency of this code is measured, and the overall code performance on the Delta is compared with that on Cray supercomputers. It is shown that their code runs with a high parallel efficiency of ≥ 95% for large size problems. The particle push time achieved is 115 nsecs/particle/time step for 162 million particles on 512 nodes. Comparing with the performance on a single processor Cray C90, this represents a factor of 58 speedup. The code uses a finite-difference leap frog method for field solve which is significantly more efficient than fast fourier transforms on parallel computers. The performance of this code on the 128 node Cray T3D will also be discussed

  4. Revisiting Intel Xeon Phi optimization of Thompson cloud microphysics scheme in Weather Research and Forecasting (WRF) model

    Science.gov (United States)

    Mielikainen, Jarno; Huang, Bormin; Huang, Allen

    2015-10-01

    The Thompson cloud microphysics scheme is a sophisticated cloud microphysics scheme in the Weather Research and Forecasting (WRF) model. The scheme is very suitable for massively parallel computation as there are no interactions among horizontal grid points. Compared to the earlier microphysics schemes, the Thompson scheme incorporates a large number of improvements. Thus, we have optimized the speed of this important part of WRF. Intel Many Integrated Core (MIC) ushers in a new era of supercomputing speed, performance, and compatibility. It allows the developers to run code at trillions of calculations per second using the familiar programming model. In this paper, we present our results of optimizing the Thompson microphysics scheme on Intel Many Integrated Core Architecture (MIC) hardware. The Intel Xeon Phi coprocessor is the first product based on Intel MIC architecture, and it consists of up to 61 cores connected by a high performance on-die bidirectional interconnect. The coprocessor supports all important Intel development tools. Thus, the development environment is familiar one to a vast number of CPU developers. Although, getting a maximum performance out of MICs will require using some novel optimization techniques. New optimizations for an updated Thompson scheme are discusses in this paper. The optimizations improved the performance of the original Thompson code on Xeon Phi 7120P by a factor of 1.8x. Furthermore, the same optimizations improved the performance of the Thompson on a dual socket configuration of eight core Intel Xeon E5-2670 CPUs by a factor of 1.8x compared to the original Thompson code.

  5. The reciprocity law concerning light dose relationships applied to BisGMA/TEGDMA photopolymers: theoretical analysis and experimental characterization.

    Science.gov (United States)

    Wydra, James W; Cramer, Neil B; Stansbury, Jeffrey W; Bowman, Christopher N

    2014-06-01

    A model BisGMA/TEGDMA unfilled resin was utilized to investigate the effect of varied irradiation intensity on the photopolymerization kinetics and shrinkage stress evolution, as a means for evaluation of the reciprocity relationship. Functional group conversion was determined by FTIR spectroscopy and polymerization shrinkage stress was obtained by a tensometer. Samples were polymerized with UV light from an EXFO Acticure with 0.1wt% photoinitiator. A one-dimensional kinetic model was utilized to predict the conversion-dose relationship. As irradiation intensity increased, conversion decreased at a constant irradiation dose and the overall dose required to achieve full conversion increased. Methacrylate conversion ranged from 64±2% at 3mW/cm(2) to 78±1% at 24mW/cm(2) while the final shrinkage stress varied from 2.4±0.1MPa to 3.0±0.1MPa. The ultimate conversion and shrinkage stress levels achieved were dependent not only upon dose but also the irradiation intensity, in contrast to an idealized reciprocity relationship. A kinetic model was utilized to analyze this behavior and provide theoretical conversion profiles versus irradiation time and dose. Analysis of the experimental and modeling results demonstrated that the polymerization kinetics do not and should not be expected to follow the reciprocity law behavior. As irradiation intensity is increased, the overall dose required to achieve full conversion also increased. Further, the ultimate conversion and shrinkage stress that are achieved are not dependent only upon dose but rather upon the irradiation intensity and corresponding polymerization rate. Copyright © 2014 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

  6. Die Zukunft der ärztlichen Weiterbildung in Deutschland – Positionspapier des Ausschusses Weiterbildung der Gesellschaft für Medizinische Ausbildung (GMA [The future of graduate medical education in Germany – Position paper of the committee on graduate medical education of the Society for Medical Education (GMA

    Directory of Open Access Journals (Sweden)

    Weih, Markus

    2013-05-01

    Full Text Available [english] The German graduate medical education system is going through an important phase of changes. Besides the ongoing reform of the national guidelines for graduate medical education (Musterweiterbildungsordnung, other factors like societal and demographic changes, health and research policy reforms also play a central role for the future and competitiveness of graduate medical education.With this position paper, the committee on graduate medical education of the Society for Medical Education (GMA would like to point out some central questions for this process and support the current discourse.As an interprofessional and interdisciplinary scientific society, the GMA has the resources to contribute in a meaningful way to an evidence-based and future-oriented graduate medical education strategy.In this position paper, we use four key questions with regards to educational goals, quality assurance, teaching competence and policy requirements to address the core issues for the future of graduate medical education in Germany. The GMA sees its task in contributing to the necessary reform processes as the only German speaking scientific society in the field of medical education.[german] Die ärztliche Weiterbildung in Deutschland befindet sich im Umbruch. Neben der aktuellen Reform der Musterweiterbildungsordnung spielen gesellschaftliche, demographische, gesundheits- und forschungspolitische Faktoren eine wichtige Rolle für die Zukunft und Konkurrenzfähigkeit der ärztlichen Weiterbildung.Der Ausschuss für Weiterbildung der Gesellschaft für Medizinische Ausbildung (GMA möchte mit diesem Positionspapier auf zentrale Fragen in diesem Prozess aufmerksam machen und Impulse für den aktuellen Diskurs geben.Dabei kann die GMA als interdisziplinäre und interprofessionelle Fachgesellschaft wichtige Beiträge zu einer evidenzbasierten und zukunftsorientierten Weiterbildungsstrategie liefern.Im vorliegenden Papier werden anhand von vier Leitfragen zu

  7. Transitioning to Intel-based Linux Servers in the Payload Operations Integration Center

    Science.gov (United States)

    Guillebeau, P. L.

    2004-01-01

    The MSFC Payload Operations Integration Center (POIC) is the focal point for International Space Station (ISS) payload operations. The POIC contains the facilities, hardware, software and communication interface necessary to support payload operations. ISS ground system support for processing and display of real-time spacecraft and telemetry and command data has been operational for several years. The hardware components were reaching end of life and vendor costs were increasing while ISS budgets were becoming severely constrained. Therefore it has been necessary to migrate the Unix portions of our ground systems to commodity priced Intel-based Linux servers. hardware architecture including networks, data storage, and highly available resources. This paper will concentrate on the Linux migration implementation for the software portion of our ground system. The migration began with 3.5 million lines of code running on Unix platforms with separate servers for telemetry, command, Payload information management systems, web, system control, remote server interface and databases. The Intel-based system is scheduled to be available for initial operational use by August 2004 The overall migration to Intel-based Linux servers in the control center involves changes to the This paper will address the Linux migration study approach including the proof of concept, criticality of customer buy-in and importance of beginning with POSlX compliant code. It will focus on the development approach explaining the software lifecycle. Other aspects of development will be covered including phased implementation, interim milestones and metrics measurements and reporting mechanisms. This paper will also address the testing approach covering all levels of testing including development, development integration, IV&V, user beta testing and acceptance testing. Test results including performance numbers compared with Unix servers will be included. need for a smooth transition while maintaining

  8. High-throughput sockets over RDMA for the Intel Xeon Phi coprocessor

    CERN Document Server

    Santogidis, Aram

    2017-01-01

    In this paper we describe the design, implementation and performance of Trans4SCIF, a user-level socket-like transport library for the Intel Xeon Phi coprocessor. Trans4SCIF library is primarily intended for high-throughput applications. It uses RDMA transfers over the native SCIF support, in a way that is transparent for the application, which has the illusion of using conventional stream sockets. We also discuss the integration of Trans4SCIF with the ZeroMQ messaging library, used extensively by several applications running at CERN. We show that this can lead to a substantial, up to 3x, increase of application throughput compared to the default TCP/IP transport option.

  9. GW Calculations of Materials on the Intel Xeon-Phi Architecture

    Science.gov (United States)

    Deslippe, Jack; da Jornada, Felipe H.; Vigil-Fowler, Derek; Biller, Ariel; Chelikowsky, James R.; Louie, Steven G.

    Intel Xeon-Phi processors are expected to power a large number of High-Performance Computing (HPC) systems around the United States and the world in the near future. We evaluate the ability of GW and pre-requisite Density Functional Theory (DFT) calculations for materials on utilizing the Xeon-Phi architecture. We describe the optimization process and performance improvements achieved. We find that the GW method, like other higher level Many-Body methods beyond standard local/semilocal approximations to Kohn-Sham DFT, is particularly well suited for many-core architectures due to the ability to exploit a large amount of parallelism over plane-waves, band-pairs and frequencies. Support provided by the SCIDAC program, Department of Energy, Office of Science, Advanced Scientic Computing Research and Basic Energy Sciences. Grant Numbers DE-SC0008877 (Austin) and DE-AC02-05CH11231 (LBNL).

  10. Heterogeneous High Throughput Scientific Computing with APM X-Gene and Intel Xeon Phi

    CERN Document Server

    Abdurachmanov, David; Elmer, Peter; Eulisse, Giulio; Knight, Robert; Muzaffar, Shahzad

    2014-01-01

    Electrical power requirements will be a constraint on the future growth of Distributed High Throughput Computing (DHTC) as used by High Energy Physics. Performance-per-watt is a critical metric for the evaluation of computer architectures for cost- efficient computing. Additionally, future performance growth will come from heterogeneous, many-core, and high computing density platforms with specialized processors. In this paper, we examine the Intel Xeon Phi Many Integrated Cores (MIC) co-processor and Applied Micro X-Gene ARMv8 64-bit low-power server system-on-a-chip (SoC) solutions for scientific computing applications. We report our experience on software porting, performance and energy efficiency and evaluate the potential for use of such technologies in the context of distributed computing systems such as the Worldwide LHC Computing Grid (WLCG).

  11. Heterogeneous High Throughput Scientific Computing with APM X-Gene and Intel Xeon Phi

    Science.gov (United States)

    Abdurachmanov, David; Bockelman, Brian; Elmer, Peter; Eulisse, Giulio; Knight, Robert; Muzaffar, Shahzad

    2015-05-01

    Electrical power requirements will be a constraint on the future growth of Distributed High Throughput Computing (DHTC) as used by High Energy Physics. Performance-per-watt is a critical metric for the evaluation of computer architectures for cost- efficient computing. Additionally, future performance growth will come from heterogeneous, many-core, and high computing density platforms with specialized processors. In this paper, we examine the Intel Xeon Phi Many Integrated Cores (MIC) co-processor and Applied Micro X-Gene ARMv8 64-bit low-power server system-on-a-chip (SoC) solutions for scientific computing applications. We report our experience on software porting, performance and energy efficiency and evaluate the potential for use of such technologies in the context of distributed computing systems such as the Worldwide LHC Computing Grid (WLCG).

  12. Heterogeneous High Throughput Scientific Computing with APM X-Gene and Intel Xeon Phi

    International Nuclear Information System (INIS)

    Abdurachmanov, David; Bockelman, Brian; Elmer, Peter; Eulisse, Giulio; Muzaffar, Shahzad; Knight, Robert

    2015-01-01

    Electrical power requirements will be a constraint on the future growth of Distributed High Throughput Computing (DHTC) as used by High Energy Physics. Performance-per-watt is a critical metric for the evaluation of computer architectures for cost- efficient computing. Additionally, future performance growth will come from heterogeneous, many-core, and high computing density platforms with specialized processors. In this paper, we examine the Intel Xeon Phi Many Integrated Cores (MIC) co-processor and Applied Micro X-Gene ARMv8 64-bit low-power server system-on-a-chip (SoC) solutions for scientific computing applications. We report our experience on software porting, performance and energy efficiency and evaluate the potential for use of such technologies in the context of distributed computing systems such as the Worldwide LHC Computing Grid (WLCG). (paper)

  13. Communication overhead on the Intel Paragon, IBM SP2 and Meiko CS-2

    Science.gov (United States)

    Bokhari, Shahid H.

    1995-01-01

    Interprocessor communication overhead is a crucial measure of the power of parallel computing systems-its impact can severely limit the performance of parallel programs. This report presents measurements of communication overhead on three contemporary commercial multicomputer systems: the Intel Paragon, the IBM SP2 and the Meiko CS-2. In each case the time to communicate between processors is presented as a function of message length. The time for global synchronization and memory access is discussed. The performance of these machines in emulating hypercubes and executing random pairwise exchanges is also investigated. It is shown that the interprocessor communication time depends heavily on the specific communication pattern required. These observations contradict the commonly held belief that communication overhead on contemporary machines is independent of the placement of tasks on processors. The information presented in this report permits the evaluation of the efficiency of parallel algorithm implementations against standard baselines.

  14. A performance study of sparse Cholesky factorization on INTEL iPSC/860

    Science.gov (United States)

    Zubair, M.; Ghose, M.

    1992-01-01

    The problem of Cholesky factorization of a sparse matrix has been very well investigated on sequential machines. A number of efficient codes exist for factorizing large unstructured sparse matrices. However, there is a lack of such efficient codes on parallel machines in general, and distributed machines in particular. Some of the issues that are critical to the implementation of sparse Cholesky factorization on a distributed memory parallel machine are ordering, partitioning and mapping, load balancing, and ordering of various tasks within a processor. Here, we focus on the effect of various partitioning schemes on the performance of sparse Cholesky factorization on the Intel iPSC/860. Also, a new partitioning heuristic for structured as well as unstructured sparse matrices is proposed, and its performance is compared with other schemes.

  15. Plasma turbulence calculations on the Intel iPSC/860 (rx) hypercube

    International Nuclear Information System (INIS)

    Lynch, V.E.; Ruiter, J.R.

    1990-01-01

    One approach to improving the real-time efficiency of plasma turbulence calculations is to use a parallel algorithm. A serial algorithm used for plasma turbulence calculations was modified to allocate a radial region in each node. In this way, convolutions at a fixed radius are performed in parallel, and communication is limited to boundary values for each radial region. For a semi-implicity numerical scheme (tridiagonal matrix solver), there is a factor of 3 improvement in efficiency with the Intel iPSC/860 machine using 64 processors over a single-processor Cray-II. For block-tridiagonal matrix cases (fully implicit code), a second parallelization takes place. The Fourier components are distributed in nodes. In each node, the block-tridiagonal matrix is inverted for each of allocated Fourier components. The algorithm for this second case has not yet been optimized. 10 refs., 4 figs

  16. Performance Evaluation of Multithreaded Geant4 Simulations Using an Intel Xeon Phi Cluster

    Directory of Open Access Journals (Sweden)

    P. Schweitzer

    2015-01-01

    Full Text Available The objective of this study is to evaluate the performances of Intel Xeon Phi hardware accelerators for Geant4 simulations, especially for multithreaded applications. We present the complete methodology to guide users for the compilation of their Geant4 applications on Phi processors. Then, we propose series of benchmarks to compare the performance of Xeon CPUs and Phi processors for a Geant4 example dedicated to the simulation of electron dose point kernels, the TestEm12 example. First, we compare a distributed execution of a sequential version of the Geant4 example on both architectures before evaluating the multithreaded version of the Geant4 example. If Phi processors demonstrated their ability to accelerate computing time (till a factor 3.83 when distributing sequential Geant4 simulations, we do not reach the same level of speedup when considering the multithreaded version of the Geant4 example.

  17. Evaluation of the Intel iWarp parallel processor for space flight applications

    Science.gov (United States)

    Hine, Butler P., III; Fong, Terrence W.

    1993-01-01

    The potential of a DARPA-sponsored advanced processor, the Intel iWarp, for use in future SSF Data Management Systems (DMS) upgrades is evaluated through integration into the Ames DMS testbed and applications testing. The iWarp is a distributed, parallel computing system well suited for high performance computing applications such as matrix operations and image processing. The system architecture is modular, supports systolic and message-based computation, and is capable of providing massive computational power in a low-cost, low-power package. As a consequence, the iWarp offers significant potential for advanced space-based computing. This research seeks to determine the iWarp's suitability as a processing device for space missions. In particular, the project focuses on evaluating the ease of integrating the iWarp into the SSF DMS baseline architecture and the iWarp's ability to support computationally stressing applications representative of SSF tasks.

  18. Lattice QCD with Domain Decomposition on Intel Xeon Phi Co-Processors

    Energy Technology Data Exchange (ETDEWEB)

    Heybrock, Simon; Joo, Balint; Kalamkar, Dhiraj D; Smelyanskiy, Mikhail; Vaidyanathan, Karthikeyan; Wettig, Tilo; Dubey, Pradeep

    2014-12-01

    The gap between the cost of moving data and the cost of computing continues to grow, making it ever harder to design iterative solvers on extreme-scale architectures. This problem can be alleviated by alternative algorithms that reduce the amount of data movement. We investigate this in the context of Lattice Quantum Chromodynamics and implement such an alternative solver algorithm, based on domain decomposition, on Intel Xeon Phi co-processor (KNC) clusters. We demonstrate close-to-linear on-chip scaling to all 60 cores of the KNC. With a mix of single- and half-precision the domain-decomposition method sustains 400-500 Gflop/s per chip. Compared to an optimized KNC implementation of a standard solver [1], our full multi-node domain-decomposition solver strong-scales to more nodes and reduces the time-to-solution by a factor of 5.

  19. Using Intel Xeon Phi to accelerate the WRF TEMF planetary boundary layer scheme

    Science.gov (United States)

    Mielikainen, Jarno; Huang, Bormin; Huang, Allen

    2014-05-01

    The Weather Research and Forecasting (WRF) model is designed for numerical weather prediction and atmospheric research. The WRF software infrastructure consists of several components such as dynamic solvers and physics schemes. Numerical models are used to resolve the large-scale flow. However, subgrid-scale parameterizations are for an estimation of small-scale properties (e.g., boundary layer turbulence and convection, clouds, radiation). Those have a significant influence on the resolved scale due to the complex nonlinear nature of the atmosphere. For the cloudy planetary boundary layer (PBL), it is fundamental to parameterize vertical turbulent fluxes and subgrid-scale condensation in a realistic manner. A parameterization based on the Total Energy - Mass Flux (TEMF) that unifies turbulence and moist convection components produces a better result that the other PBL schemes. For that reason, the TEMF scheme is chosen as the PBL scheme we optimized for Intel Many Integrated Core (MIC), which ushers in a new era of supercomputing speed, performance, and compatibility. It allows the developers to run code at trillions of calculations per second using the familiar programming model. In this paper, we present our optimization results for TEMF planetary boundary layer scheme. The optimizations that were performed were quite generic in nature. Those optimizations included vectorization of the code to utilize vector units inside each CPU. Furthermore, memory access was improved by scalarizing some of the intermediate arrays. The results show that the optimization improved MIC performance by 14.8x. Furthermore, the optimizations increased CPU performance by 2.6x compared to the original multi-threaded code on quad core Intel Xeon E5-2603 running at 1.8 GHz. Compared to the optimized code running on a single CPU socket the optimized MIC code is 6.2x faster.

  20. The effect of the polymerization initiator and light source on the elution of residual Bis-GMA and TEGDMA monomers: A study using liquid chromatography with UV detection.

    Science.gov (United States)

    Denis, Aline B; Diagone, Cristina A; Plepis, Ana M G; Viana, Rommel B

    2015-12-05

    A method for the extraction and quantification of two residual monomers, bisphenol glycidyl dimethacrylate (Bis-GMA) and triethylene glycol dimethacrylate (TEGDMA), that were evaluated using high efficiency liquid chromatography with UV detection was developed and validated in this study. Three types of solvents were applied in the extraction of the monomers (methanol, ethanol and acetonitrile), where the highest extraction efficiency was obtained using acetonitrile. The different resins were prepared by photoactivation of Bis-GMA and TEGDMA monomers. Additionally, the effects of the addition of two photoinitiators (camphorquinone (CQ) and phenyl propanodione (PPD) and that of a co-initiator (N,N-dimethyl-p-toluidine) were also analyzed. When only the CQ photoinitiator was used, a smaller amount of residual monomers was obtained, whereas a larger amount was obtained with PPD. When the two photoinitiators were used in the same matrix, however, no significant changes were observed in relation to the amount of residual TEGDMA monomers. For the addition of the co-initiator, there were no large changes in the extraction of residual monomers. The effect of the two photoactivation sources (halogen lamp and LED) led to small differences in the elution of the two monomers, although all of the resins differed significantly when photoactivated with a LED. Quantum chemical calculations using Density Functional Theory were carried out to characterize several molecular properties of each monomer. Copyright © 2015 Elsevier B.V. All rights reserved.

  1. Kinetic Parameters during Bis-GMA and TEGDMA Monomer Polymerization by ATR-FTIR: The Influence of Photoinitiator and Light Curing Source

    Directory of Open Access Journals (Sweden)

    Aline B. Denis

    2016-01-01

    Full Text Available This study aimed to analyze the kinetic parameters of two monomers using attenuated total reflectance Fourier transform infrared (ATR-FTIR: 2,2-bis-[4-(2-hydroxy-3-methacryloxypropyl-1-oxy-phenyl] propane (Bis-GMA and triethylene glycol dimethacrylate (TEGDMA. The following were calculated to evaluate the kinetic parameters: maximum conversion rate (Rpmax, time at the maximum polymerization rate (tmax, conversion at Rpmax, and total conversion recorded at the maximum conversion point after 300 s. Camphorquinone (CQ and phenyl propanedione (PPD were used in this study as photoinitiators, whereas N,N-dimethyl-p-toluidine (DMPT amine was used as a coinitiator. LED apparatus and halogen lamp were used in turn to evaluate the effect that light source had on the monomer kinetics. The mass concentration ratio for the three resin preparations was 0.7 : 0.3 for Bis-GMA and TEGDMA: R1 (CQ + DMPT, R2 (PPD + DMPT, and R3 (PPD + CQ + DMPT. The PPD association with the CQ photoinitiator altered the polymerization kinetics compared to a resin containing only the CQ photoinitiator. The light sources exhibited no significant differences for tmax of R1 and R3. Resins containing only the PPD initiator exhibited a higher tmax than those containing only CQ. However, the Rpmax decreased for resins containing the PPD photoinitiator.

  2. Konsensusstatement "Praktische Fertigkeiten im Medizinstudium" – ein Positionspapier des GMA-Ausschusses für praktische Fertigkeiten [A Consensus Statement on Practical Skills in Medical School – a position paper by the GMA Committee on Practical Skills

    Directory of Open Access Journals (Sweden)

    Schnabel, Kai P.

    2011-11-01

    standardisieren. Auf Initiative der deutschsprachigen Skills Labs wurde der GMA-Ausschuss für praktische Fertigkeiten gegründet, der einen kompetenzbasierten Lernzielkatalog entwickelte, dessen Entstehung und Struktur hier beschrieben wird.Ziel des Kataloges ist es, die praktischen Fertigkeiten im Medizinstudium zu definieren und damit den Fakultäten eine rationale Planungsgrundlage für die zur Vermittlung praktischer Fertigkeiten notwendigen Ressourcen zu geben.Methodik: Aufbauend auf schon vorhandenen deutschsprachigen Lernzielkatalogen wurde mittels einem mehrfach iterativem Kondensationsprozesses, der der Erarbeitung von S1-Leitlinien entspricht, vorgegangen, um eine breite fachliche und politische Abstützung zu erhalten. Ergebnisse: Es wurden 289 verschiedene praktische Lernziele identifiziert, die zwölf verschiedenen Organsystemen, drei Grenzbereichen zu anderen Kompetenzbereichen und einem Bereich mit organsystemübergreifenden Fertigkeiten zugeordnet. Sie wurden drei verschiedenen zeitlichen und drei verschiedenen Tiefendimensionen zugeordnet und mit dem Schweizer und dem Österreichischem Pendant abgeglichen. Diskussion: Das vorliegende Konsensusstatement kann den deutschen Fakultäten eine Grundlage zur Planung der Vermittlung praktischer Fertigkeiten bieten und bildet einen wichtigen Schritt zu einem nationalen Standard medizinischer Lernziele.Blick in die Zukunft: Das Konsensusstatement soll einen formativen Effekt auf die medizinischen Fakultäten haben, ihre praktischen Unterrichtsinhalte entsprechend zu vermitteln und die Ressourcen danach zu planen.

  3. Acceleration of Monte Carlo simulation of photon migration in complex heterogeneous media using Intel many-integrated core architecture.

    Science.gov (United States)

    Gorshkov, Anton V; Kirillin, Mikhail Yu

    2015-08-01

    Over two decades, the Monte Carlo technique has become a gold standard in simulation of light propagation in turbid media, including biotissues. Technological solutions provide further advances of this technique. The Intel Xeon Phi coprocessor is a new type of accelerator for highly parallel general purpose computing, which allows execution of a wide range of applications without substantial code modification. We present a technical approach of porting our previously developed Monte Carlo (MC) code for simulation of light transport in tissues to the Intel Xeon Phi coprocessor. We show that employing the accelerator allows reducing computational time of MC simulation and obtaining simulation speed-up comparable to GPU. We demonstrate the performance of the developed code for simulation of light transport in the human head and determination of the measurement volume in near-infrared spectroscopy brain sensing.

  4. Performance Evaluation of an Intel Haswell- and Ivy Bridge-Based Supercomputer Using Scientific and Engineering Applications

    Science.gov (United States)

    Saini, Subhash; Hood, Robert T.; Chang, Johnny; Baron, John

    2016-01-01

    We present a performance evaluation conducted on a production supercomputer of the Intel Xeon Processor E5- 2680v3, a twelve-core implementation of the fourth-generation Haswell architecture, and compare it with Intel Xeon Processor E5-2680v2, an Ivy Bridge implementation of the third-generation Sandy Bridge architecture. Several new architectural features have been incorporated in Haswell including improvements in all levels of the memory hierarchy as well as improvements to vector instructions and power management. We critically evaluate these new features of Haswell and compare with Ivy Bridge using several low-level benchmarks including subset of HPCC, HPCG and four full-scale scientific and engineering applications. We also present a model to predict the performance of HPCG and Cart3D within 5%, and Overflow within 10% accuracy.

  5. GNAQPMS v1.1: accelerating the Global Nested Air Quality Prediction Modeling System (GNAQPMS) on Intel Xeon Phi processors

    OpenAIRE

    H. Wang; H. Wang; H. Wang; H. Wang; H. Chen; H. Chen; Q. Wu; Q. Wu; J. Lin; X. Chen; X. Xie; R. Wang; R. Wang; X. Tang; Z. Wang

    2017-01-01

    The Global Nested Air Quality Prediction Modeling System (GNAQPMS) is the global version of the Nested Air Quality Prediction Modeling System (NAQPMS), which is a multi-scale chemical transport model used for air quality forecast and atmospheric environmental research. In this study, we present the porting and optimisation of GNAQPMS on a second-generation Intel Xeon Phi processor, codenamed Knights Landing (KNL). Compared with the first-generation Xeon Phi coprocessor (code...

  6. Student Intern Ben Freed Competes as Finalist in Intel STS Competition, Three Other Interns Named Semifinalists | Poster

    Science.gov (United States)

    By Ashley DeVine, Staff Writer Werner H. Kirstin (WHK) student intern Ben Freed was one of 40 finalists to compete in the Intel Science Talent Search (STS) in Washington, DC, in March. “It was seven intense days of interacting with amazing judges and incredibly smart and interesting students. We met President Obama, and then the MIT astronomy lab named minor planets after each

  7. Evaluating the transport layer of the ALFA framework for the Intel(®) Xeon Phi(™) Coprocessor

    OpenAIRE

    Santogidis, Aram; Hirstius, Andreas; Lalis, Spyros

    2015-01-01

    The ALFA framework supports the software development of major High Energy Physics experiments. As part of our research effort to optimize the transport layer of ALFA, we focus on profiling its data transfer performance for inter-node communication on the Intel Xeon Phi Coprocessor. In this article we present the collected performance measurements with the related analysis of the results. The optimization opportunities that are discovered, help us to formulate the future plans of enabling high...

  8. Computationally efficient implementation of sarse-tap FIR adaptive filters with tap-position control on intel IA-32 processors

    OpenAIRE

    Hirano, Akihiro; Nakayama, Kenji

    2008-01-01

    This paper presents an computationally ef cient implementation of sparse-tap FIR adaptive lters with tapposition control on Intel IA-32 processors with single-instruction multiple-data (SIMD) capability. In order to overcome randomorder memory access which prevents a ectorization, a blockbased processing and a re-ordering buffer are introduced. A dynamic register allocation and the use of memory-to-register operations help the maximization of the loop-unrolling level. Up to 66percent speedup ...

  9. Efficient irregular wavefront propagation algorithms on Intel® Xeon Phi™.

    Science.gov (United States)

    Gomes, Jeremias M; Teodoro, George; de Melo, Alba; Kong, Jun; Kurc, Tahsin; Saltz, Joel H

    2015-10-01

    We investigate the execution of the Irregular Wavefront Propagation Pattern (IWPP), a fundamental computing structure used in several image analysis operations, on the Intel ® Xeon Phi ™ co-processor. An efficient implementation of IWPP on the Xeon Phi is a challenging problem because of IWPP's irregularity and the use of atomic instructions in the original IWPP algorithm to resolve race conditions. On the Xeon Phi, the use of SIMD and vectorization instructions is critical to attain high performance. However, SIMD atomic instructions are not supported. Therefore, we propose a new IWPP algorithm that can take advantage of the supported SIMD instruction set. We also evaluate an alternate storage container (priority queue) to track active elements in the wavefront in an effort to improve the parallel algorithm efficiency. The new IWPP algorithm is evaluated with Morphological Reconstruction and Imfill operations as use cases. Our results show performance improvements of up to 5.63 × on top of the original IWPP due to vectorization. Moreover, the new IWPP achieves speedups of 45.7 × and 1.62 × , respectively, as compared to efficient CPU and GPU implementations.

  10. OpenMP-accelerated SWAT simulation using Intel C and FORTRAN compilers: Development and benchmark

    Science.gov (United States)

    Ki, Seo Jin; Sugimura, Tak; Kim, Albert S.

    2015-02-01

    We developed a practical method to accelerate execution of Soil and Water Assessment Tool (SWAT) using open (free) computational resources. The SWAT source code (rev 622) was recompiled using a non-commercial Intel FORTRAN compiler in Ubuntu 12.04 LTS Linux platform, and newly named iOMP-SWAT in this study. GNU utilities of make, gprof, and diff were used to develop the iOMP-SWAT package, profile memory usage, and check identicalness of parallel and serial simulations. Among 302 SWAT subroutines, the slowest routines were identified using GNU gprof, and later modified using Open Multiple Processing (OpenMP) library in an 8-core shared memory system. In addition, a C wrapping function was used to rapidly set large arrays to zero by cross compiling with the original SWAT FORTRAN package. A universal speedup ratio of 2.3 was achieved using input data sets of a large number of hydrological response units. As we specifically focus on acceleration of a single SWAT run, the use of iOMP-SWAT for parameter calibrations will significantly improve the performance of SWAT optimization.

  11. Optimizing meridional advection of the Advanced Research WRF (ARW) dynamics for Intel Xeon Phi coprocessor

    Science.gov (United States)

    Mielikainen, Jarno; Huang, Bormin; Huang, Allen H.-L.

    2015-05-01

    The most widely used community weather forecast and research model in the world is the Weather Research and Forecast (WRF) model. Two distinct varieties of WRF exist. The one we are interested is the Advanced Research WRF (ARW) is an experimental, advanced research version featuring very high resolution. The WRF Nonhydrostatic Mesoscale Model (WRF-NMM) has been designed for forecasting operations. WRF consists of dynamics code and several physics modules. The WRF-ARW core is based on an Eulerian solver for the fully compressible nonhydrostatic equations. In the paper, we optimize a meridional (north-south direction) advection subroutine for Intel Xeon Phi coprocessor. Advection is of the most time consuming routines in the ARW dynamics core. It advances the explicit perturbation horizontal momentum equations by adding in the large-timestep tendency along with the small timestep pressure gradient tendency. We will describe the challenges we met during the development of a high-speed dynamics code subroutine for MIC architecture. Furthermore, lessons learned from the code optimization process will be discussed. The results show that the optimizations improved performance of the original code on Xeon Phi 7120P by a factor of 1.2x.

  12. Software and DVFS Tuning for Performance and Energy-Efficiency on Intel KNL Processors

    Directory of Open Access Journals (Sweden)

    Enrico Calore

    2018-06-01

    Full Text Available Energy consumption of processors and memories is quickly becoming a limiting factor in the deployment of large computing systems. For this reason, it is important to understand the energy performance of these processors and to study strategies allowing their use in the most efficient way. In this work, we focus on the computing and energy performance of the Knights Landing Xeon Phi, the latest Intel many-core architecture processor for HPC applications. We consider the 64-core Xeon Phi 7230 and profile its performance and energy efficiency using both its on-chip MCDRAM and the off-chip DDR4 memory as the main storage for application data. As a benchmark application, we use a lattice Boltzmann code heavily optimized for this architecture and implemented using several different arrangements of the application data in memory (data-layouts, in short. We also assess the dependence of energy consumption on data-layouts, memory configurations (DDR4 or MCDRAM and the number of threads per core. We finally consider possible trade-offs between computing performance and energy efficiency, tuning the clock frequency of the processor using the Dynamic Voltage and Frequency Scaling (DVFS technique.

  13. A comparison of SuperLU solvers on the intel MIC architecture

    Science.gov (United States)

    Tuncel, Mehmet; Duran, Ahmet; Celebi, M. Serdar; Akaydin, Bora; Topkaya, Figen O.

    2016-10-01

    In many science and engineering applications, problems may result in solving a sparse linear system AX=B. For example, SuperLU_MCDT, a linear solver, was used for the large penta-diagonal matrices for 2D problems and hepta-diagonal matrices for 3D problems, coming from the incompressible blood flow simulation (see [1]). It is important to test the status and potential improvements of state-of-the-art solvers on new technologies. In this work, sequential, multithreaded and distributed versions of SuperLU solvers (see [2]) are examined on the Intel Xeon Phi coprocessors using offload programming model at the EURORA cluster of CINECA in Italy. We consider a portfolio of test matrices containing patterned matrices from UFMM ([3]) and randomly located matrices. This architecture can benefit from high parallelism and large vectors. We find that the sequential SuperLU benefited up to 45 % performance improvement from the offload programming depending on the sparse matrix type and the size of transferred and processed data.

  14. Modeling high-temperature superconductors and metallic alloys on the Intel IPSC/860

    Science.gov (United States)

    Geist, G. A.; Peyton, B. W.; Shelton, W. A.; Stocks, G. M.

    Oak Ridge National Laboratory has embarked on several computational Grand Challenges, which require the close cooperation of physicists, mathematicians, and computer scientists. One of these projects is the determination of the material properties of alloys from first principles and, in particular, the electronic structure of high-temperature superconductors. While the present focus of the project is on superconductivity, the approach is general enough to permit study of other properties of metallic alloys such as strength and magnetic properties. This paper describes the progress to date on this project. We include a description of a self-consistent KKR-CPA method, parallelization of the model, and the incorporation of a dynamic load balancing scheme into the algorithm. We also describe the development and performance of a consolidated KKR-CPA code capable of running on CRAYs, workstations, and several parallel computers without source code modification. Performance of this code on the Intel iPSC/860 is also compared to a CRAY 2, CRAY YMP, and several workstations. Finally, some density of state calculations of two perovskite superconductors are given.

  15. Parallel spatial direct numerical simulations on the Intel iPSC/860 hypercube

    Science.gov (United States)

    Joslin, Ronald D.; Zubair, Mohammad

    1993-01-01

    The implementation and performance of a parallel spatial direct numerical simulation (PSDNS) approach on the Intel iPSC/860 hypercube is documented. The direct numerical simulation approach is used to compute spatially evolving disturbances associated with the laminar-to-turbulent transition in boundary-layer flows. The feasibility of using the PSDNS on the hypercube to perform transition studies is examined. The results indicate that the direct numerical simulation approach can effectively be parallelized on a distributed-memory parallel machine. By increasing the number of processors nearly ideal linear speedups are achieved with nonoptimized routines; slower than linear speedups are achieved with optimized (machine dependent library) routines. This slower than linear speedup results because the Fast Fourier Transform (FFT) routine dominates the computational cost and because the routine indicates less than ideal speedups. However with the machine-dependent routines the total computational cost decreases by a factor of 4 to 5 compared with standard FORTRAN routines. The computational cost increases linearly with spanwise wall-normal and streamwise grid refinements. The hypercube with 32 processors was estimated to require approximately twice the amount of Cray supercomputer single processor time to complete a comparable simulation; however it is estimated that a subgrid-scale model which reduces the required number of grid points and becomes a large-eddy simulation (PSLES) would reduce the computational cost and memory requirements by a factor of 10 over the PSDNS. This PSLES implementation would enable transition simulations on the hypercube at a reasonable computational cost.

  16. Efficient irregular wavefront propagation algorithms on Intel® Xeon Phi™

    Science.gov (United States)

    Gomes, Jeremias M.; Teodoro, George; de Melo, Alba; Kong, Jun; Kurc, Tahsin; Saltz, Joel H.

    2016-01-01

    We investigate the execution of the Irregular Wavefront Propagation Pattern (IWPP), a fundamental computing structure used in several image analysis operations, on the Intel® Xeon Phi™ co-processor. An efficient implementation of IWPP on the Xeon Phi is a challenging problem because of IWPP’s irregularity and the use of atomic instructions in the original IWPP algorithm to resolve race conditions. On the Xeon Phi, the use of SIMD and vectorization instructions is critical to attain high performance. However, SIMD atomic instructions are not supported. Therefore, we propose a new IWPP algorithm that can take advantage of the supported SIMD instruction set. We also evaluate an alternate storage container (priority queue) to track active elements in the wavefront in an effort to improve the parallel algorithm efficiency. The new IWPP algorithm is evaluated with Morphological Reconstruction and Imfill operations as use cases. Our results show performance improvements of up to 5.63× on top of the original IWPP due to vectorization. Moreover, the new IWPP achieves speedups of 45.7× and 1.62×, respectively, as compared to efficient CPU and GPU implementations. PMID:27298591

  17. Deployment of the OSIRIS EM-PIC code on the Intel Knights Landing architecture

    Science.gov (United States)

    Fonseca, Ricardo

    2017-10-01

    Electromagnetic particle-in-cell (EM-PIC) codes such as OSIRIS have found widespread use in modelling the highly nonlinear and kinetic processes that occur in several relevant plasma physics scenarios, ranging from astrophysical settings to high-intensity laser plasma interaction. Being computationally intensive, these codes require large scale HPC systems, and a continuous effort in adapting the algorithm to new hardware and computing paradigms. In this work, we report on our efforts on deploying the OSIRIS code on the new Intel Knights Landing (KNL) architecture. Unlike the previous generation (Knights Corner), these boards are standalone systems, and introduce several new features, include the new AVX-512 instructions and on-package MCDRAM. We will focus on the parallelization and vectorization strategies followed, as well as memory management, and present a detailed performance evaluation of code performance in comparison with the CPU code. This work was partially supported by Fundaçã para a Ciência e Tecnologia (FCT), Portugal, through Grant No. PTDC/FIS-PLA/2940/2014.

  18. Plasma Science and Applications at the Intel Science Fair: A Retrospective

    Science.gov (United States)

    Berry, Lee

    2009-11-01

    For the past five years, the Coalition for Plasma Science (CPS) has presented an award for a plasma project at the Intel International Science and Engineering Fair (ISEF). Eligible projects have ranged from grape-based plasma production in a microwave oven to observation of the effects of viscosity in a fluid model of quark-gluon plasma. Most projects have been aimed at applications, including fusion, thrusters, lighting, materials processing, and GPS improvements. However diagnostics (spectroscopy), technology (magnets), and theory (quark-gluon plasmas) have also been represented. All of the CPS award-winning projects so far have been based on experiments, with two awards going to women students and three to men. Since the award was initiated, both the number and quality of plasma projects has increased. The CPS expects this trend to continue, and looks forward to continuing its work with students who are excited about the possibilities of plasma. You too can share this excitement by judging at the 2010 fair in San Jose on May 11-12.

  19. Implementation of 5-layer thermal diffusion scheme in weather research and forecasting model with Intel Many Integrated Cores

    Science.gov (United States)

    Huang, Melin; Huang, Bormin; Huang, Allen H.

    2014-10-01

    For weather forecasting and research, the Weather Research and Forecasting (WRF) model has been developed, consisting of several components such as dynamic solvers and physical simulation modules. WRF includes several Land- Surface Models (LSMs). The LSMs use atmospheric information, the radiative and precipitation forcing from the surface layer scheme, the radiation scheme, and the microphysics/convective scheme all together with the land's state variables and land-surface properties, to provide heat and moisture fluxes over land and sea-ice points. The WRF 5-layer thermal diffusion simulation is an LSM based on the MM5 5-layer soil temperature model with an energy budget that includes radiation, sensible, and latent heat flux. The WRF LSMs are very suitable for massively parallel computation as there are no interactions among horizontal grid points. The features, efficient parallelization and vectorization essentials, of Intel Many Integrated Core (MIC) architecture allow us to optimize this WRF 5-layer thermal diffusion scheme. In this work, we present the results of the computing performance on this scheme with Intel MIC architecture. Our results show that the MIC-based optimization improved the performance of the first version of multi-threaded code on Xeon Phi 5110P by a factor of 2.1x. Accordingly, the same CPU-based optimizations improved the performance on Intel Xeon E5- 2603 by a factor of 1.6x as compared to the first version of multi-threaded code.

  20. Evaluation of the Intel Xeon Phi 7120 and NVIDIA K80 as accelerators for two-dimensional panel codes.

    Science.gov (United States)

    Einkemmer, Lukas

    2017-01-01

    To optimize the geometry of airfoils for a specific application is an important engineering problem. In this context genetic algorithms have enjoyed some success as they are able to explore the search space without getting stuck in local optima. However, these algorithms require the computation of aerodynamic properties for a significant number of airfoil geometries. Consequently, for low-speed aerodynamics, panel methods are most often used as the inner solver. In this paper we evaluate the performance of such an optimization algorithm on modern accelerators (more specifically, the Intel Xeon Phi 7120 and the NVIDIA K80). For that purpose, we have implemented an optimized version of the algorithm on the CPU and Xeon Phi (based on OpenMP, vectorization, and the Intel MKL library) and on the GPU (based on CUDA and the MAGMA library). We present timing results for all codes and discuss the similarities and differences between the three implementations. Overall, we observe a speedup of approximately 2.5 for adding an Intel Xeon Phi 7120 to a dual socket workstation and a speedup between 3.4 and 3.8 for adding a NVIDIA K80 to a dual socket workstation.

  1. Performance Evaluation of Computation and Communication Kernels of the Fast Multipole Method on Intel Manycore Architecture

    KAUST Repository

    AbdulJabbar, Mustafa Abdulmajeed

    2017-07-31

    Manycore optimizations are essential for achieving performance worthy of anticipated exascale systems. Utilization of manycore chips is inevitable to attain the desired floating point performance of these energy-austere systems. In this work, we revisit ExaFMM, the open source Fast Multiple Method (FMM) library, in light of highly tuned shared-memory parallelization and detailed performance analysis on the new highly parallel Intel manycore architecture, Knights Landing (KNL). We assess scalability and performance gain using task-based parallelism of the FMM tree traversal. We also provide an in-depth analysis of the most computationally intensive part of the traversal kernel (i.e., the particle-to-particle (P2P) kernel), by comparing its performance across KNL and Broadwell architectures. We quantify different configurations that exploit the on-chip 512-bit vector units within different task-based threading paradigms. MPI communication-reducing and NUMA-aware approaches for the FMM’s global tree data exchange are examined with different cluster modes of KNL. By applying several algorithm- and architecture-aware optimizations for FMM, we show that the N-Body kernel on 256 threads of KNL achieves on average 2.8× speedup compared to the non-vectorized version, whereas on 56 threads of Broadwell, it achieves on average 2.9× speedup. In addition, the tree traversal kernel on KNL scales monotonically up to 256 threads with task-based programming models. The MPI-based communication-reducing algorithms show expected improvements of the data locality across the KNL on-chip network.

  2. Performance Evaluation of Computation and Communication Kernels of the Fast Multipole Method on Intel Manycore Architecture

    KAUST Repository

    AbdulJabbar, Mustafa Abdulmajeed; Al Farhan, Mohammed; Yokota, Rio; Keyes, David E.

    2017-01-01

    Manycore optimizations are essential for achieving performance worthy of anticipated exascale systems. Utilization of manycore chips is inevitable to attain the desired floating point performance of these energy-austere systems. In this work, we revisit ExaFMM, the open source Fast Multiple Method (FMM) library, in light of highly tuned shared-memory parallelization and detailed performance analysis on the new highly parallel Intel manycore architecture, Knights Landing (KNL). We assess scalability and performance gain using task-based parallelism of the FMM tree traversal. We also provide an in-depth analysis of the most computationally intensive part of the traversal kernel (i.e., the particle-to-particle (P2P) kernel), by comparing its performance across KNL and Broadwell architectures. We quantify different configurations that exploit the on-chip 512-bit vector units within different task-based threading paradigms. MPI communication-reducing and NUMA-aware approaches for the FMM’s global tree data exchange are examined with different cluster modes of KNL. By applying several algorithm- and architecture-aware optimizations for FMM, we show that the N-Body kernel on 256 threads of KNL achieves on average 2.8× speedup compared to the non-vectorized version, whereas on 56 threads of Broadwell, it achieves on average 2.9× speedup. In addition, the tree traversal kernel on KNL scales monotonically up to 256 threads with task-based programming models. The MPI-based communication-reducing algorithms show expected improvements of the data locality across the KNL on-chip network.

  3. Thread-level parallelization and optimization of NWChem for the Intel MIC architecture

    Energy Technology Data Exchange (ETDEWEB)

    Shan, Hongzhang [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Williams, Samuel [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); de Jong, Wibe [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Oliker, Leonid [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2015-01-01

    In the multicore era it was possible to exploit the increase in on-chip parallelism by simply running multiple MPI processes per chip. Unfortunately, manycore processors' greatly increased thread- and data-level parallelism coupled with a reduced memory capacity demand an altogether different approach. In this paper we explore augmenting two NWChem modules, triples correction of the CCSD(T) and Fock matrix construction, with OpenMP in order that they might run efficiently on future manycore architectures. As the next NERSC machine will be a self-hosted Intel MIC (Xeon Phi) based supercomputer, we leverage an existing MIC testbed at NERSC to evaluate our experiments. In order to proxy the fact that future MIC machines will not have a host processor, we run all of our experiments in native mode. We found that while straightforward application of OpenMP to the deep loop nests associated with the tensor contractions of CCSD(T) was sufficient in attaining high performance, significant e ort was required to safely and efeciently thread the TEXAS integral package when constructing the Fock matrix. Ultimately, our new MPI+OpenMP hybrid implementations attain up to 65× better performance for the triples part of the CCSD(T) due in large part to the fact that the limited on-card memory limits the existing MPI implementation to a single process per card. Additionally, we obtain up to 1.6× better performance on Fock matrix constructions when compared with the best MPI implementations running multiple processes per card.

  4. Using Intel's Knight Landing Processor to Accelerate Global Nested Air Quality Prediction Modeling System (GNAQPMS) Model

    Science.gov (United States)

    Wang, H.; Chen, H.; Chen, X.; Wu, Q.; Wang, Z.

    2016-12-01

    The Global Nested Air Quality Prediction Modeling System for Hg (GNAQPMS-Hg) is a global chemical transport model coupled Hg transport module to investigate the mercury pollution. In this study, we present our work of transplanting the GNAQPMS model on Intel Xeon Phi processor, Knights Landing (KNL) to accelerate the model. KNL is the second-generation product adopting Many Integrated Core Architecture (MIC) architecture. Compared with the first generation Knight Corner (KNC), KNL has more new hardware features, that it can be used as unique processor as well as coprocessor with other CPU. According to the Vtune tool, the high overhead modules in GNAQPMS model have been addressed, including CBMZ gas chemistry, advection and convection module, and wet deposition module. These high overhead modules were accelerated by optimizing code and using new techniques of KNL. The following optimized measures was done: 1) Changing the pure MPI parallel mode to hybrid parallel mode with MPI and OpenMP; 2.Vectorizing the code to using the 512-bit wide vector computation unit. 3. Reducing unnecessary memory access and calculation. 4. Reducing Thread Local Storage (TLS) for common variables with each OpenMP thread in CBMZ. 5. Changing the way of global communication from files writing and reading to MPI functions. After optimization, the performance of GNAQPMS is greatly increased both on CPU and KNL platform, the single-node test showed that optimized version has 2.6x speedup on two sockets CPU platform and 3.3x speedup on one socket KNL platform compared with the baseline version code, which means the KNL has 1.29x speedup when compared with 2 sockets CPU platform.

  5. Navier-Stokes Aerodynamic Simulation of the V-22 Osprey on the Intel Paragon MPP

    Science.gov (United States)

    Vadyak, Joseph; Shrewsbury, George E.; Narramore, Jim C.; Montry, Gary; Holst, Terry; Kwak, Dochan (Technical Monitor)

    1995-01-01

    The paper will describe the Development of a general three-dimensional multiple grid zone Navier-Stokes flowfield simulation program (ENS3D-MPP) designed for efficient execution on the Intel Paragon Massively Parallel Processor (MPP) supercomputer, and the subsequent application of this method to the prediction of the viscous flowfield about the V-22 Osprey tiltrotor vehicle. The flowfield simulation code solves the thin Layer or full Navier-Stoke's equation - for viscous flow modeling, or the Euler equations for inviscid flow modeling on a structured multi-zone mesh. In the present paper only viscous simulations will be shown. The governing difference equations are solved using a time marching implicit approximate factorization method with either TVD upwind or central differencing used for the convective terms and central differencing used for the viscous diffusion terms. Steady state or Lime accurate solutions can be calculated. The present paper will focus on steady state applications, although time accurate solution analysis is the ultimate goal of this effort. Laminar viscosity is calculated using Sutherland's law and the Baldwin-Lomax two layer algebraic turbulence model is used to compute the eddy viscosity. The Simulation method uses an arbitrary block, curvilinear grid topology. An automatic grid adaption scheme is incorporated which concentrates grid points in high density gradient regions. A variety of user-specified boundary conditions are available. This paper will present the application of the scalable and superscalable versions to the steady state viscous flow analysis of the V-22 Osprey using a multiple zone global mesh. The mesh consists of a series of sheared cartesian grid blocks with polar grids embedded within to better simulate the wing tip mounted nacelle. MPP solutions will be shown in comparison to equivalent Cray C-90 results and also in comparison to experimental data. Discussions on meshing considerations, wall clock execution time

  6. Thread-Level Parallelization and Optimization of NWChem for the Intel MIC Architecture

    Energy Technology Data Exchange (ETDEWEB)

    Shan, Hongzhang; Williams, Samuel; Jong, Wibe de; Oliker, Leonid

    2014-10-10

    In the multicore era it was possible to exploit the increase in on-chip parallelism by simply running multiple MPI processes per chip. Unfortunately, manycore processors' greatly increased thread- and data-level parallelism coupled with a reduced memory capacity demand an altogether different approach. In this paper we explore augmenting two NWChem modules, triples correction of the CCSD(T) and Fock matrix construction, with OpenMP in order that they might run efficiently on future manycore architectures. As the next NERSC machine will be a self-hosted Intel MIC (Xeon Phi) based supercomputer, we leverage an existing MIC testbed at NERSC to evaluate our experiments. In order to proxy the fact that future MIC machines will not have a host processor, we run all of our experiments in tt native mode. We found that while straightforward application of OpenMP to the deep loop nests associated with the tensor contractions of CCSD(T) was sufficient in attaining high performance, significant effort was required to safely and efficiently thread the TEXAS integral package when constructing the Fock matrix. Ultimately, our new MPI OpenMP hybrid implementations attain up to 65x better performance for the triples part of the CCSD(T) due in large part to the fact that the limited on-card memory limits the existing MPI implementation to a single process per card. Additionally, we obtain up to 1.6x better performance on Fock matrix constructions when compared with the best MPI implementations running multiple processes per card.

  7. Nationaler Kompetenzbasierter Lernzielkatalog Medizin (NKLM für Deutschland: Zusammenarbeit der Gesellschaft für Medizinische Ausbildung (GMA und des Medizinischen Fakultätentages (MFT [National Competence-Based Learning Objectives for Undergraduate Medical Education (NKLM in Germany: Cooperation of the Association for Medical Education (GMA and the Association of Medical Faculties in Germany (MFT

    Directory of Open Access Journals (Sweden)

    Hahn, Eckhart G.

    2009-08-01

    Full Text Available [english] The Framework for Qualifications of the European Higher Education Area (FQ-EHEA; Bologna Process and the European Qualifications Framework for Lifelong Learning (EQF-LLL; Lisbon Process are competence-driven frameworks for vocational and higher education programmes in need for defined learning objectives. In the field of medical education, The Netherlands and Switzerland have developed national catalogues for undergraduate medical training, which are competence-based and compatible with a two-cycle curriculum comprised of a Bachelor in Medicine and a Master in Medicine. In Germany, virtually all medical organizations, last not least the Association of Medical Faculties (MFT, have voted against the application of the two-cycle (and the three-cycle curriculum to medical undergraduate education. A standstill of the European processes will not be accepted in the political arena, and a proposition was made by the Conference of German Ministers of Higher Education to develop a medical qualification framework for Germany, asking the Association for Medical Education (GMA and the MFT to join forces. This is not possible without consented national learning objectives derived from the professional context of physicians. The GMA has teamed up with the MFT to develop National Competence-Based Learning Objectives for Undergraduate Medical Education (NKLM in Germany (see Figure 1 to fulfill these needs.

  8. GNAQPMS v1.1: accelerating the Global Nested Air Quality Prediction Modeling System (GNAQPMS) on Intel Xeon Phi processors

    Science.gov (United States)

    Wang, Hui; Chen, Huansheng; Wu, Qizhong; Lin, Junmin; Chen, Xueshun; Xie, Xinwei; Wang, Rongrong; Tang, Xiao; Wang, Zifa

    2017-08-01

    The Global Nested Air Quality Prediction Modeling System (GNAQPMS) is the global version of the Nested Air Quality Prediction Modeling System (NAQPMS), which is a multi-scale chemical transport model used for air quality forecast and atmospheric environmental research. In this study, we present the porting and optimisation of GNAQPMS on a second-generation Intel Xeon Phi processor, codenamed Knights Landing (KNL). Compared with the first-generation Xeon Phi coprocessor (codenamed Knights Corner, KNC), KNL has many new hardware features such as a bootable processor, high-performance in-package memory and ISA compatibility with Intel Xeon processors. In particular, we describe the five optimisations we applied to the key modules of GNAQPMS, including the CBM-Z gas-phase chemistry, advection, convection and wet deposition modules. These optimisations work well on both the KNL 7250 processor and the Intel Xeon E5-2697 V4 processor. They include (1) updating the pure Message Passing Interface (MPI) parallel mode to the hybrid parallel mode with MPI and OpenMP in the emission, advection, convection and gas-phase chemistry modules; (2) fully employing the 512 bit wide vector processing units (VPUs) on the KNL platform; (3) reducing unnecessary memory access to improve cache efficiency; (4) reducing the thread local storage (TLS) in the CBM-Z gas-phase chemistry module to improve its OpenMP performance; and (5) changing the global communication from writing/reading interface files to MPI functions to improve the performance and the parallel scalability. These optimisations greatly improved the GNAQPMS performance. The same optimisations also work well for the Intel Xeon Broadwell processor, specifically E5-2697 v4. Compared with the baseline version of GNAQPMS, the optimised version was 3.51 × faster on KNL and 2.77 × faster on the CPU. Moreover, the optimised version ran at 26 % lower average power on KNL than on the CPU. With the combined performance and energy

  9. GNAQPMS v1.1: accelerating the Global Nested Air Quality Prediction Modeling System (GNAQPMS on Intel Xeon Phi processors

    Directory of Open Access Journals (Sweden)

    H. Wang

    2017-08-01

    Full Text Available The Global Nested Air Quality Prediction Modeling System (GNAQPMS is the global version of the Nested Air Quality Prediction Modeling System (NAQPMS, which is a multi-scale chemical transport model used for air quality forecast and atmospheric environmental research. In this study, we present the porting and optimisation of GNAQPMS on a second-generation Intel Xeon Phi processor, codenamed Knights Landing (KNL. Compared with the first-generation Xeon Phi coprocessor (codenamed Knights Corner, KNC, KNL has many new hardware features such as a bootable processor, high-performance in-package memory and ISA compatibility with Intel Xeon processors. In particular, we describe the five optimisations we applied to the key modules of GNAQPMS, including the CBM-Z gas-phase chemistry, advection, convection and wet deposition modules. These optimisations work well on both the KNL 7250 processor and the Intel Xeon E5-2697 V4 processor. They include (1 updating the pure Message Passing Interface (MPI parallel mode to the hybrid parallel mode with MPI and OpenMP in the emission, advection, convection and gas-phase chemistry modules; (2 fully employing the 512 bit wide vector processing units (VPUs on the KNL platform; (3 reducing unnecessary memory access to improve cache efficiency; (4 reducing the thread local storage (TLS in the CBM-Z gas-phase chemistry module to improve its OpenMP performance; and (5 changing the global communication from writing/reading interface files to MPI functions to improve the performance and the parallel scalability. These optimisations greatly improved the GNAQPMS performance. The same optimisations also work well for the Intel Xeon Broadwell processor, specifically E5-2697 v4. Compared with the baseline version of GNAQPMS, the optimised version was 3.51 × faster on KNL and 2.77 × faster on the CPU. Moreover, the optimised version ran at 26 % lower average power on KNL than on the CPU. With the combined

  10. Emmarcar el debat: Lliure expressió contra propietat intel·lectual, els propers cinquanta anys

    Directory of Open Access Journals (Sweden)

    Eben Moglen

    2007-02-01

    Full Text Available

    El Prof. Moglen explica i analitza, des d'una perspectiva històrica, la profunda revolució social i legal que resulta de la tecnologia digital quan aquesta s'aplica a tots els camps: programari, música i tot tipus de creacions. En concret, explica la manera en què la tecnologia digital està forçant una modificació substancial (desaparició dels sistemes de propietat intel·lectual i fa prediccions per al futur pròxim dels mercats de la PI.

  11. Evaluation of the OpenCL AES Kernel using the Intel FPGA SDK for OpenCL

    Energy Technology Data Exchange (ETDEWEB)

    Jin, Zheming [Argonne National Lab. (ANL), Argonne, IL (United States); Yoshii, Kazutomo [Argonne National Lab. (ANL), Argonne, IL (United States); Finkel, Hal [Argonne National Lab. (ANL), Argonne, IL (United States); Cappello, Franck [Argonne National Lab. (ANL), Argonne, IL (United States)

    2017-04-20

    The OpenCL standard is an open programming model for accelerating algorithms on heterogeneous computing system. OpenCL extends the C-based programming language for developing portable codes on different platforms such as CPU, Graphics processing units (GPUs), Digital Signal Processors (DSPs) and Field Programmable Gate Arrays (FPGAs). The Intel FPGA SDK for OpenCL is a suite of tools that allows developers to abstract away the complex FPGA-based development flow for a high-level software development flow. Users can focus on the design of hardware-accelerated kernel functions in OpenCL and then direct the tools to generate the low-level FPGA implementations. The approach makes the FPGA-based development more accessible to software users as the needs for hybrid computing using CPUs and FPGAs are increasing. It can also significantly reduce the hardware development time as users can evaluate different ideas with high-level language without deep FPGA domain knowledge. In this report, we evaluate the performance of the kernel using the Intel FPGA SDK for OpenCL and Nallatech 385A FPGA board. Compared to the M506 module, the board provides more hardware resources for a larger design exploration space. The kernel performance is measured with the compute kernel throughput, an upper bound to the FPGA throughput. The report presents the experimental results in details. The Appendix lists the kernel source code.

  12. Evaluation of the Single-precision Floatingpoint Vector Add Kernel Using the Intel FPGA SDK for OpenCL

    Energy Technology Data Exchange (ETDEWEB)

    Jin, Zheming [Argonne National Lab. (ANL), Argonne, IL (United States); Yoshii, Kazutomo [Argonne National Lab. (ANL), Argonne, IL (United States); Finkel, Hal [Argonne National Lab. (ANL), Argonne, IL (United States); Cappello, Franck [Argonne National Lab. (ANL), Argonne, IL (United States)

    2017-04-20

    Open Computing Language (OpenCL) is a high-level language that enables software programmers to explore Field Programmable Gate Arrays (FPGAs) for application acceleration. The Intel FPGA software development kit (SDK) for OpenCL allows a user to specify applications at a high level and explore the performance of low-level hardware acceleration. In this report, we present the FPGA performance and power consumption results of the single-precision floating-point vector add OpenCL kernel using the Intel FPGA SDK for OpenCL on the Nallatech 385A FPGA board. The board features an Arria 10 FPGA. We evaluate the FPGA implementations using the compute unit duplication and kernel vectorization optimization techniques. On the Nallatech 385A FPGA board, the maximum compute kernel bandwidth we achieve is 25.8 GB/s, approximately 76% of the peak memory bandwidth. The power consumption of the FPGA device when running the kernels ranges from 29W to 42W.

  13. Efficient sparse matrix-matrix multiplication for computing periodic responses by shooting method on Intel Xeon Phi

    Science.gov (United States)

    Stoykov, S.; Atanassov, E.; Margenov, S.

    2016-10-01

    Many of the scientific applications involve sparse or dense matrix operations, such as solving linear systems, matrix-matrix products, eigensolvers, etc. In what concerns structural nonlinear dynamics, the computations of periodic responses and the determination of stability of the solution are of primary interest. Shooting method iswidely used for obtaining periodic responses of nonlinear systems. The method involves simultaneously operations with sparse and dense matrices. One of the computationally expensive operations in the method is multiplication of sparse by dense matrices. In the current work, a new algorithm for sparse matrix by dense matrix products is presented. The algorithm takes into account the structure of the sparse matrix, which is obtained by space discretization of the nonlinear Mindlin's plate equation of motion by the finite element method. The algorithm is developed to use the vector engine of Intel Xeon Phi coprocessors. It is compared with the standard sparse matrix by dense matrix algorithm and the one developed by Intel MKL and it is shown that by considering the properties of the sparse matrix better algorithms can be developed.

  14. Time-efficient simulations of tight-binding electronic structures with Intel Xeon PhiTM many-core processors

    Science.gov (United States)

    Ryu, Hoon; Jeong, Yosang; Kang, Ji-Hoon; Cho, Kyu Nam

    2016-12-01

    Modelling of multi-million atomic semiconductor structures is important as it not only predicts properties of physically realizable novel materials, but can accelerate advanced device designs. This work elaborates a new Technology-Computer-Aided-Design (TCAD) tool for nanoelectronics modelling, which uses a sp3d5s∗ tight-binding approach to describe multi-million atomic structures, and simulate electronic structures with high performance computing (HPC), including atomic effects such as alloy and dopant disorders. Being named as Quantum simulation tool for Advanced Nanoscale Devices (Q-AND), the tool shows nice scalability on traditional multi-core HPC clusters implying the strong capability of large-scale electronic structure simulations, particularly with remarkable performance enhancement on latest clusters of Intel Xeon PhiTM coprocessors. A review of the recent modelling study conducted to understand an experimental work of highly phosphorus-doped silicon nanowires, is presented to demonstrate the utility of Q-AND. Having been developed via Intel Parallel Computing Center project, Q-AND will be open to public to establish a sound framework of nanoelectronics modelling with advanced HPC clusters of a many-core base. With details of the development methodology and exemplary study of dopant electronics, this work will present a practical guideline for TCAD development to researchers in the field of computational nanoelectronics.

  15. A parallel implementation of particle tracking with space charge effects on an INTEL iPSC/860

    International Nuclear Information System (INIS)

    Chang, L.; Bourianoff, G.; Cole, B.; Machida, S.

    1993-05-01

    Particle-tracking simulation is one of the scientific applications that is well-suited to parallel computations. At the Superconducting Super Collider, it has been theoretically and empirically demonstrated that particle tracking on a designed lattice can achieve very high parallel efficiency on a MIMD Intel iPSC/860 machine. The key to such success is the realization that the particles can be tracked independently without considering their interaction. The perfectly parallel nature of particle tracking is broken if the interaction effects between particles are included. The space charge introduces an electromagnetic force that will affect the motion of tracked particles in 3-D space. For accurate modeling of the beam dynamics with space charge effects, one needs to solve three-dimensional Maxwell field equations, usually by a particle-in-cell (PIC) algorithm. This will require each particle to communicate with its neighbor grids to compute the momentum changes at each time step. It is expected that the 3-D PIC method will degrade parallel efficiency of particle-tracking implementation on any parallel computer. In this paper, we describe an efficient scheme for implementing particle tracking with space charge effects on an INTEL iPSC/860 machine. Experimental results show that a parallel efficiency of 75% can be obtained

  16. Reflective memory recorder upgrade: an opportunity to benchmark PowerPC and Intel architectures for real time

    Science.gov (United States)

    Abuter, Roberto; Tischer, Helmut; Frahm, Robert

    2014-07-01

    Several high frequency loops are required to run the VLTI (Very Large Telescope Interferometer) 2, e.g. for fringe tracking11, 5, angle tracking, vibration cancellation, data capture. All these loops rely on low latency real time computers based on the VME bus, Motorola PowerPC14 hardware architecture. In this context, one highly demanding application in terms of cycle time, latency and data transfer volume is the VLTI centralized recording facility, so called, RMN recorder1 (Reflective Memory Recorder). This application captures and transfers data flowing through the distributed memory of the system in real time. Some of the VLTI data producers are running with frequencies up to 8 KHz. With the evolution from first generation instruments like MIDI3, PRIMA5, and AMBER4 which use one or two baselines, to second generation instruments like MATISSE10 and GRAVITY9 which will use all six baselines simultaneously, the quantity of signals has increased by, at least, a factor of six. This has led to a significant overload of the RMN recorder1 which has reached the natural limits imposed by the underlying hardware. At the same time, new, more powerful computers, based on the Intel multicore families of CPUs and PCI buses have become available. With the purpose of improving the performance of the RMN recorder1 application and in order to make it capable of coping with the demands of the new generation instruments, a slightly modified implementation has been developed and integrated into an Intel based multicore computer15 running the VxWorks17 real time operating system. The core of the application is based on the standard VLT software framework for instruments13. The real time task reads from the reflective memory using the onboard DMA access12 and captured data is transferred to the outside world via a TCP socket on a dedicated Ethernet connection. The diversity of the software and hardware that are involved makes this application suitable as a benchmarking platform. A

  17. Intel Many Integrated Core (MIC) architecture optimization strategies for a memory-bound Weather Research and Forecasting (WRF) Goddard microphysics scheme

    Science.gov (United States)

    Mielikainen, Jarno; Huang, Bormin; Huang, Allen H.

    2014-10-01

    The Goddard cloud microphysics scheme is a sophisticated cloud microphysics scheme in the Weather Research and Forecasting (WRF) model. The WRF is a widely used weather prediction system in the world. It development is a done in collaborative around the globe. The Goddard microphysics scheme is very suitable for massively parallel computation as there are no interactions among horizontal grid points. Compared to the earlier microphysics schemes, the Goddard scheme incorporates a large number of improvements. Thus, we have optimized the code of this important part of WRF. In this paper, we present our results of optimizing the Goddard microphysics scheme on Intel Many Integrated Core Architecture (MIC) hardware. The Intel Xeon Phi coprocessor is the first product based on Intel MIC architecture, and it consists of up to 61 cores connected by a high performance on-die bidirectional interconnect. The Intel MIC is capable of executing a full operating system and entire programs rather than just kernels as the GPU do. The MIC coprocessor supports all important Intel development tools. Thus, the development environment is familiar one to a vast number of CPU developers. Although, getting a maximum performance out of MICs will require using some novel optimization techniques. Those optimization techniques are discusses in this paper. The results show that the optimizations improved performance of the original code on Xeon Phi 7120P by a factor of 4.7x. Furthermore, the same optimizations improved performance on a dual socket Intel Xeon E5-2670 system by a factor of 2.8x compared to the original code.

  18. Core Competencies for Medical Teachers (KLM) – A Position Paper of the GMA Committee on Personal and Organizational Development in Teaching

    Science.gov (United States)

    Görlitz, Anja; Ebert, Thomas; Bauer, Daniel; Grasl, Matthäus; Hofer, Matthias; Lammerding-Köppel, Maria; Fabry, Götz

    2015-01-01

    Recent developments in medical education have created increasing challenges for medical teachers which is why the majority of German medical schools already offer educational and instructional skills trainings for their teaching staff. However, to date no framework for educational core competencies for medical teachers exists that might serve as guidance for the qualification of the teaching faculty. Against the background of the discussion about competency based medical education and based upon the international literature, the GMA Committee for Faculty and Organizational Development in Teaching developed a model of core teaching competencies for medical teachers. This framework is designed not only to provide guidance with regard to individual qualification profiles but also to support further advancement of the content, training formats and evaluation of faculty development initiatives and thus, to establish uniform quality criteria for such initiatives in German-speaking medical schools. The model comprises a framework of six competency fields, subdivided into competency components and learning objectives. Additional examples of their use in medical teaching scenarios illustrate and clarify each specific teaching competency. The model has been designed for routine application in medical schools and is thought to be complemented consecutively by additional competencies for teachers with special duties and responsibilities in a future step. PMID:26038688

  19. Parallel computation for biological sequence comparison: comparing a portable model to the native model for the Intel Hypercube.

    Science.gov (United States)

    Nadkarni, P M; Miller, P L

    1991-01-01

    A parallel program for inter-database sequence comparison was developed on the Intel Hypercube using two models of parallel programming. One version was built using machine-specific Hypercube parallel programming commands. The other version was built using Linda, a machine-independent parallel programming language. The two versions of the program provide a case study comparing these two approaches to parallelization in an important biological application area. Benchmark tests with both programs gave comparable results with a small number of processors. As the number of processors was increased, the Linda version was somewhat less efficient. The Linda version was also run without change on Network Linda, a virtual parallel machine running on a network of desktop workstations.

  20. Analysis of the Intel 386 and i486 microprocessors for the Space Station Freedom Data Management System

    Science.gov (United States)

    Liu, Yuan-Kwei

    1991-01-01

    The feasibility is analyzed of upgrading the Intel 386 microprocessor, which has been proposed as the baseline processor for the Space Station Freedom (SSF) Data Management System (DMS), to the more advanced i486 microprocessors. The items compared between the two processors include the instruction set architecture, power consumption, the MIL-STD-883C Class S (Space) qualification schedule, and performance. The advantages of the i486 over the 386 are (1) lower power consumption; and (2) higher floating point performance. The i486 on-chip cache does not have parity check or error detection and correction circuitry. The i486 with on-chip cache disabled, however, has lower integer performance than the 386 without cache, which is the current DMS design choice. Adding cache to the 386/386 DX memory hierachy appears to be the most beneficial change to the current DMS design at this time.

  1. La responsabilitat davant la intel·ligència artificial en el comerç electrònic

    OpenAIRE

    Martín i Palomas, Elisabet

    2015-01-01

    Es planteja en aquesta tesi l'efecte produït sobre la responsabilitat derivada de les accions realitzades autònomament per sistemes dotats d'intel·ligència artificial, sense la participació directa de cap ésser humà, en els temes més directament relacionats amb el comerç electrònic. Per a això s'analitzen les activitats realitzades per algunes de les principals empreses internacionals de comerç electrònic, com el grup nord-americà eBay o el grup xinès Alibaba. Després de desenvolupar els prin...

  2. Evaluating the networking characteristics of the Cray XC-40 Intel Knights Landing-based Cori supercomputer at NERSC

    Energy Technology Data Exchange (ETDEWEB)

    Doerfler, Douglas [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Austin, Brian [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Cook, Brandon [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Deslippe, Jack [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Kandalla, Krishna [Cray Inc, Bloomington, MN (United States); Mendygral, Peter [Cray Inc, Bloomington, MN (United States)

    2017-09-12

    There are many potential issues associated with deploying the Intel Xeon Phi™ (code named Knights Landing [KNL]) manycore processor in a large-scale supercomputer. One in particular is the ability to fully utilize the high-speed communications network, given that the serial performance of a Xeon Phi TM core is a fraction of a Xeon®core. In this paper, we take a look at the trade-offs associated with allocating enough cores to fully utilize the Aries high-speed network versus cores dedicated to computation, e.g., the trade-off between MPI and OpenMP. In addition, we evaluate new features of Cray MPI in support of KNL, such as internode optimizations. We also evaluate one-sided programming models such as Unified Parallel C. We quantify the impact of the above trade-offs and features using a suite of National Energy Research Scientific Computing Center applications.

  3. Les multituds intel·ligents com a generadores de dades massives : la intel·ligència col·lectiva al servei de la innovació social

    Directory of Open Access Journals (Sweden)

    Sanz, Sandra

    2015-06-01

    Full Text Available Les últimes dècades es registra un increment de mobilitzacions socials organitzades, intervingudes, narrades i coordinades a través de les TIC. Són mostra de multituds intel·ligents (smart mobs que s'aprofiten dels nous mitjans de comunicació per organitzar-se. Tant pel nombre de missatges intercanviats i generats com per les pròpies interaccions generades, aquestes multituds intel·ligents es converteixen en objecte de les dades massives. La seva anàlisi a partir de les possibilitats que brinda l'enginyeria de dades pot contribuir a detectar idees construïdes com també sabers compartits fruit de la intel·ligència col·lectiva. Aquest fet afavoriria la reutilització d'aquesta informació per incrementar el coneixement del col·lectiu i contribuir al desenvolupament de la innovació social. És per això que en aquest article s'assenyalen els interrogants i les limitacions que encara presenten aquestes anàlisis i es posa en relleu la necessitat d'aprofundir en el desenvolupament de nous mètodes i tècniques d'anàlisi.En las últimas décadas se registra un incremento de movilizaciones sociales organizadas, mediadas, narradas y coordinadas a través de TICs. Son muestra de smart mobs o multitudes inteligentes que se aprovechan de los nuevos medios de comunicación para organizarse. Tanto por el número de mensajes intercambiados y generados como por las propias interacciones generadas, estas multitudes inteligentes se convierten en objeto del big data. Su análisis a partir de las posibilidades que brinda la ingeniería de datos puede contribuir a detectar ideas construidas así como saberes compartidos fruto de la inteligencia colectiva. Ello favorecería la reutilización de esta información para incrementar el conocimiento del colectivo y contribuir al desarrollo de la innovación social. Es por ello que en este artículo se señalan los interrogantes y limitaciones que todavía presentan estos análisis y se pone de relieve la

  4. OpenMP GNU and Intel Fortran programs for solving the time-dependent Gross-Pitaevskii equation

    Science.gov (United States)

    Young-S., Luis E.; Muruganandam, Paulsamy; Adhikari, Sadhan K.; Lončar, Vladimir; Vudragović, Dušan; Balaž, Antun

    2017-11-01

    We present Open Multi-Processing (OpenMP) version of Fortran 90 programs for solving the Gross-Pitaevskii (GP) equation for a Bose-Einstein condensate in one, two, and three spatial dimensions, optimized for use with GNU and Intel compilers. We use the split-step Crank-Nicolson algorithm for imaginary- and real-time propagation, which enables efficient calculation of stationary and non-stationary solutions, respectively. The present OpenMP programs are designed for computers with multi-core processors and optimized for compiling with both commercially-licensed Intel Fortran and popular free open-source GNU Fortran compiler. The programs are easy to use and are elaborated with helpful comments for the users. All input parameters are listed at the beginning of each program. Different output files provide physical quantities such as energy, chemical potential, root-mean-square sizes, densities, etc. We also present speedup test results for new versions of the programs. Program files doi:http://dx.doi.org/10.17632/y8zk3jgn84.2 Licensing provisions: Apache License 2.0 Programming language: OpenMP GNU and Intel Fortran 90. Computer: Any multi-core personal computer or workstation with the appropriate OpenMP-capable Fortran compiler installed. Number of processors used: All available CPU cores on the executing computer. Journal reference of previous version: Comput. Phys. Commun. 180 (2009) 1888; ibid.204 (2016) 209. Does the new version supersede the previous version?: Not completely. It does supersede previous Fortran programs from both references above, but not OpenMP C programs from Comput. Phys. Commun. 204 (2016) 209. Nature of problem: The present Open Multi-Processing (OpenMP) Fortran programs, optimized for use with commercially-licensed Intel Fortran and free open-source GNU Fortran compilers, solve the time-dependent nonlinear partial differential (GP) equation for a trapped Bose-Einstein condensate in one (1d), two (2d), and three (3d) spatial dimensions for

  5. Modelagem matemática do processo de soldagem GMAW: transferência por vôo livre Mathematical modeling of GMA welding: free fligth transfer

    Directory of Open Access Journals (Sweden)

    Ivan José de Santana

    2011-09-01

    Full Text Available Este artigo descreve a concepção e validação de um modelo matemático direcionado à soldagem GMAW. O modelo permite a predição de alguns parâmetros de soldagem, assim como o comportamento do processo em condições operacionais de transferência metálica por vôo livre. Este modelo foi baseado em um conjunto de equações, que descrevem as características operacionais da fonte de energia, as quedas de tensão que ocorrem no arco elétrico e nos componentes do circuito de soldagem, e em um balanço de energia na ponta do arame. A validação do modelo envolveu testes de soldagem mecanizada em corpos-de-prova de aço baixo carbono, com monitoração da corrente, tensão, comprimento de arco e velocidade de alimentação de arame. O modelo mostrou-se capaz de prever,em diferentes situações, com erros inferiores a 10%, os valores médios de alguns parâmetros fundamentais no processo de soldagem GMAW (valores médios de corrente, tensão e comprimento de arco elétrico, assim como, o comportamento destes na ocorrência de mudanças operacionais.This paper describes the conception and validation of a mathematical model applied to GMA welding. This model allows predicting some welding parameters as well as process behavior for operation with free flight transfer mode. This model was based on a set of equations that describes the power source characteristics, the voltage drop along the electric arc, the welding circuit and the energy balance on the wire tip. The model validation was performed by comparing its results to experimental welding trials. In this test specimen steel of low carbon was used and the parameters welding current and voltage, speed of wire feeding and arc length were monitored. The results have shown that the model is able to correctly predict how different parameters change with alterations in wire feed, in different situations. Furthermore, welding current and voltage e arc length value were predicted with a least

  6. Evaluation of the Intel Xeon Phi Co-processor to accelerate the sensitivity map calculation for PET imaging

    Science.gov (United States)

    Dey, T.; Rodrigue, P.

    2015-07-01

    We aim to evaluate the Intel Xeon Phi coprocessor for acceleration of 3D Positron Emission Tomography (PET) image reconstruction. We focus on the sensitivity map calculation as one computational intensive part of PET image reconstruction, since it is a promising candidate for acceleration with the Many Integrated Core (MIC) architecture of the Xeon Phi. The computation of the voxels in the field of view (FoV) can be done in parallel and the 103 to 104 samples needed to calculate the detection probability of each voxel can take advantage of vectorization. We use the ray tracing kernels of the Embree project to calculate the hit points of the sample rays with the detector and in a second step the sum of the radiological path taking into account attenuation is determined. The core components are implemented using the Intel single instruction multiple data compiler (ISPC) to enable a portable implementation showing efficient vectorization either on the Xeon Phi and the Host platform. On the Xeon Phi, the calculation of the radiological path is also implemented in hardware specific intrinsic instructions (so-called `intrinsics') to allow manually-optimized vectorization. For parallelization either OpenMP and ISPC tasking (based on pthreads) are evaluated.Our implementation achieved a scalability factor of 0.90 on the Xeon Phi coprocessor (model 5110P) with 60 cores at 1 GHz. Only minor differences were found between parallelization with OpenMP and the ISPC tasking feature. The implementation using intrinsics was found to be about 12% faster than the portable ISPC version. With this version, a speedup of 1.43 was achieved on the Xeon Phi coprocessor compared to the host system (HP SL250s Gen8) equipped with two Xeon (E5-2670) CPUs, with 8 cores at 2.6 to 3.3 GHz each. Using a second Xeon Phi card the speedup could be further increased to 2.77. No significant differences were found between the results of the different Xeon Phi and the Host implementations. The examination

  7. Evaluation of the Intel Xeon Phi Co-processor to accelerate the sensitivity map calculation for PET imaging

    International Nuclear Information System (INIS)

    Dey, T.; Rodrigue, P.

    2015-01-01

    We aim to evaluate the Intel Xeon Phi coprocessor for acceleration of 3D Positron Emission Tomography (PET) image reconstruction. We focus on the sensitivity map calculation as one computational intensive part of PET image reconstruction, since it is a promising candidate for acceleration with the Many Integrated Core (MIC) architecture of the Xeon Phi. The computation of the voxels in the field of view (FoV) can be done in parallel and the 10 3 to 10 4 samples needed to calculate the detection probability of each voxel can take advantage of vectorization. We use the ray tracing kernels of the Embree project to calculate the hit points of the sample rays with the detector and in a second step the sum of the radiological path taking into account attenuation is determined. The core components are implemented using the Intel single instruction multiple data compiler (ISPC) to enable a portable implementation showing efficient vectorization either on the Xeon Phi and the Host platform. On the Xeon Phi, the calculation of the radiological path is also implemented in hardware specific intrinsic instructions (so-called 'intrinsics') to allow manually-optimized vectorization. For parallelization either OpenMP and ISPC tasking (based on pthreads) are evaluated.Our implementation achieved a scalability factor of 0.90 on the Xeon Phi coprocessor (model 5110P) with 60 cores at 1 GHz. Only minor differences were found between parallelization with OpenMP and the ISPC tasking feature. The implementation using intrinsics was found to be about 12% faster than the portable ISPC version. With this version, a speedup of 1.43 was achieved on the Xeon Phi coprocessor compared to the host system (HP SL250s Gen8) equipped with two Xeon (E5-2670) CPUs, with 8 cores at 2.6 to 3.3 GHz each. Using a second Xeon Phi card the speedup could be further increased to 2.77. No significant differences were found between the results of the different Xeon Phi and the Host implementations. The

  8. Evaluation of CHO Benchmarks on the Arria 10 FPGA using Intel FPGA SDK for OpenCL

    Energy Technology Data Exchange (ETDEWEB)

    Jin, Zheming [Argonne National Lab. (ANL), Argonne, IL (United States); Yoshii, Kazutomo [Argonne National Lab. (ANL), Argonne, IL (United States); Finkel, Hal [Argonne National Lab. (ANL), Argonne, IL (United States); Cappello, Franck [Argonne National Lab. (ANL), Argonne, IL (United States)

    2017-05-23

    The OpenCL standard is an open programming model for accelerating algorithms on heterogeneous computing system. OpenCL extends the C-based programming language for developing portable codes on different platforms such as CPU, Graphics processing units (GPUs), Digital Signal Processors (DSPs) and Field Programmable Gate Arrays (FPGAs). The Intel FPGA SDK for OpenCL is a suite of tools that allows developers to abstract away the complex FPGA-based development flow for a high-level software development flow. Users can focus on the design of hardware-accelerated kernel functions in OpenCL and then direct the tools to generate the low-level FPGA implementations. The approach makes the FPGA-based development more accessible to software users as the needs for hybrid computing using CPUs and FPGAs are increasing. It can also significantly reduce the hardware development time as users can evaluate different ideas with high-level language without deep FPGA domain knowledge. Benchmarking of OpenCL-based framework is an effective way for analyzing the performance of system by studying the execution of the benchmark applications. CHO is a suite of benchmark applications that provides support for OpenCL [1]. The authors presented CHO as an OpenCL port of the CHStone benchmark. Using Altera OpenCL (AOCL) compiler to synthesize the benchmark applications, they listed the resource usage and performance of each kernel that can be successfully synthesized by the compiler. In this report, we evaluate the resource usage and performance of the CHO benchmark applications using the Intel FPGA SDK for OpenCL and Nallatech 385A FPGA board that features an Arria 10 FPGA device. The focus of the report is to have a better understanding of the resource usage and performance of the kernel implementations using Arria-10 FPGA devices compared to Stratix-5 FPGA devices. In addition, we also gain knowledge about the limitations of the current compiler when it fails to synthesize a benchmark

  9. An efficient MPI/OpenMP parallelization of the Hartree–Fock–Roothaan method for the first generation of Intel® Xeon Phi™ processor architecture

    International Nuclear Information System (INIS)

    Mironov, Vladimir; Moskovsky, Alexander; D’Mello, Michael; Alexeev, Yuri

    2017-01-01

    The Hartree-Fock (HF) method in the quantum chemistry package GAMESS represents one of the most irregular algorithms in computation today. Major steps in the calculation are the irregular computation of electron repulsion integrals (ERIs) and the building of the Fock matrix. These are the central components of the main Self Consistent Field (SCF) loop, the key hotspot in Electronic Structure (ES) codes. By threading the MPI ranks in the official release of the GAMESS code, we not only speed up the main SCF loop (4x to 6x for large systems), but also achieve a significant (>2x) reduction in the overall memory footprint. These improvements are a direct consequence of memory access optimizations within the MPI ranks. We benchmark our implementation against the official release of the GAMESS code on the Intel R Xeon PhiTM supercomputer. Here, scaling numbers are reported on up to 7,680 cores on Intel Xeon Phi coprocessors.

  10. Experience with low-power x86 processors (Atom) for HEP usage. An initial analysis of the Intel® dual core Atom™ N330 processor

    CERN Document Server

    Balazs, G; Nowak, A; CERN. Geneva. IT Department

    2009-01-01

    In this paper we compare a system based on an Intel Atom N330 low-power processor to a modern Intel Xeon® dual-socket server using CERN IT’s standard criteria for comparing price-performance and performance per watt. The Xeon server corresponds to what is typically acquired as servers in the LHC Computing Grid. The comparisons used public pricing information from November 2008. After the introduction in section 1, section 2 describes the hardware and software setup. In section 3 we describe the power measurements we did and in section 4 we discuss the throughput performance results. In section 5 we summarize our initial conclusions. We then go on to describe our long term vision and possible future scenarios for using such low-power processors, and finally we list interesting development directions.

  11. ELT-scale Adaptive Optics real-time control with thes Intel Xeon Phi Many Integrated Core Architecture

    Science.gov (United States)

    Jenkins, David R.; Basden, Alastair; Myers, Richard M.

    2018-05-01

    We propose a solution to the increased computational demands of Extremely Large Telescope (ELT) scale adaptive optics (AO) real-time control with the Intel Xeon Phi Knights Landing (KNL) Many Integrated Core (MIC) Architecture. The computational demands of an AO real-time controller (RTC) scale with the fourth power of telescope diameter and so the next generation ELTs require orders of magnitude more processing power for the RTC pipeline than existing systems. The Xeon Phi contains a large number (≥64) of low power x86 CPU cores and high bandwidth memory integrated into a single socketed server CPU package. The increased parallelism and memory bandwidth are crucial to providing the performance for reconstructing wavefronts with the required precision for ELT scale AO. Here, we demonstrate that the Xeon Phi KNL is capable of performing ELT scale single conjugate AO real-time control computation at over 1.0kHz with less than 20μs RMS jitter. We have also shown that with a wavefront sensor camera attached the KNL can process the real-time control loop at up to 966Hz, the maximum frame-rate of the camera, with jitter remaining below 20μs RMS. Future studies will involve exploring the use of a cluster of Xeon Phis for the real-time control of the MCAO and MOAO regimes of AO. We find that the Xeon Phi is highly suitable for ELT AO real time control.

  12. Heat dissipation for the Intel Core i5 processor using multiwalled carbon-nanotube-based ethylene glycol

    International Nuclear Information System (INIS)

    Thang, Bui Hung; Trinh, Pham Van; Quang, Le Dinh; Khoi, Phan Hong; Minh, Phan Ngoc; Huong, Nguyen Thi

    2014-01-01

    Carbon nanotubes (CNTs) are some of the most valuable materials with high thermal conductivity. The thermal conductivity of individual multiwalled carbon nanotubes (MWCNTs) grown by using chemical vapor deposition is 600 ± 100 Wm -1 K -1 compared with the thermal conductivity 419 Wm -1 K -1 of Ag. Carbon-nanotube-based liquids - a new class of nanomaterials, have shown many interesting properties and distinctive features offering potential in heat dissipation applications for electronic devices, such as computer microprocessor, high power LED, etc. In this work, a multiwalled carbon-nanotube-based liquid was made of well-dispersed hydroxyl-functional multiwalled carbon nanotubes (MWCNT-OH) in ethylene glycol (EG)/distilled water (DW) solutions by using Tween-80 surfactant and an ultrasonication method. The concentration of MWCNT-OH in EG/DW solutions ranged from 0.1 to 1.2 gram/liter. The dispersion of the MWCNT-OH-based EG/DW solutions was evaluated by using a Zeta-Sizer analyzer. The MWCNT-OH-based EG/DW solutions were used as coolants in the liquid cooling system for the Intel Core i5 processor. The thermal dissipation efficiency and the thermal response of the system were evaluated by directly measuring the temperature of the micro-processor using the Core Temp software and the temperature sensors built inside the micro-processor. The results confirmed the advantages of CNTs in thermal dissipation systems for computer processors and other high-power electronic devices.

  13. Quantum Chemical Calculations Using Accelerators: Migrating Matrix Operations to the NVIDIA Kepler GPU and the Intel Xeon Phi.

    Science.gov (United States)

    Leang, Sarom S; Rendell, Alistair P; Gordon, Mark S

    2014-03-11

    Increasingly, modern computer systems comprise a multicore general-purpose processor augmented with a number of special purpose devices or accelerators connected via an external interface such as a PCI bus. The NVIDIA Kepler Graphical Processing Unit (GPU) and the Intel Phi are two examples of such accelerators. Accelerators offer peak performances that can be well above those of the host processor. How to exploit this heterogeneous environment for legacy application codes is not, however, straightforward. This paper considers how matrix operations in typical quantum chemical calculations can be migrated to the GPU and Phi systems. Double precision general matrix multiply operations are endemic in electronic structure calculations, especially methods that include electron correlation, such as density functional theory, second order perturbation theory, and coupled cluster theory. The use of approaches that automatically determine whether to use the host or an accelerator, based on problem size, is explored, with computations that are occurring on the accelerator and/or the host. For data-transfers over PCI-e, the GPU provides the best overall performance for data sizes up to 4096 MB with consistent upload and download rates between 5-5.6 GB/s and 5.4-6.3 GB/s, respectively. The GPU outperforms the Phi for both square and nonsquare matrix multiplications.

  14. Stereoscopic-3D display design: a new paradigm with Intel Adaptive Stable Image Technology [IA-SIT

    Science.gov (United States)

    Jain, Sunil

    2012-03-01

    Stereoscopic-3D (S3D) proliferation on personal computers (PC) is mired by several technical and business challenges: a) viewing discomfort due to cross-talk amongst stereo images; b) high system cost; and c) restricted content availability. Users expect S3D visual quality to be better than, or at least equal to, what they are used to enjoying on 2D in terms of resolution, pixel density, color, and interactivity. Intel Adaptive Stable Image Technology (IA-SIT) is a foundational technology, successfully developed to resolve S3D system design challenges and deliver high quality 3D visualization at PC price points. Optimizations in display driver, panel timing firmware, backlight hardware, eyewear optical stack, and synch mechanism combined can help accomplish this goal. Agnostic to refresh rate, IA-SIT will scale with shrinking of display transistors and improvements in liquid crystal and LED materials. Industry could profusely benefit from the following calls to action:- 1) Adopt 'IA-SIT S3D Mode' in panel specs (via VESA) to help panel makers monetize S3D; 2) Adopt 'IA-SIT Eyewear Universal Optical Stack' and algorithm (via CEA) to help PC peripheral makers develop stylish glasses; 3) Adopt 'IA-SIT Real Time Profile' for sub-100uS latency control (via BT Sig) to extend BT into S3D; and 4) Adopt 'IA-SIT Architecture' for Monitors and TVs to monetize via PC attach.

  15. Initial results on computational performance of Intel Many Integrated Core (MIC) architecture: implementation of the Weather and Research Forecasting (WRF) Purdue-Lin microphysics scheme

    Science.gov (United States)

    Mielikainen, Jarno; Huang, Bormin; Huang, Allen H.

    2014-10-01

    Purdue-Lin scheme is a relatively sophisticated microphysics scheme in the Weather Research and Forecasting (WRF) model. The scheme includes six classes of hydro meteors: water vapor, cloud water, raid, cloud ice, snow and graupel. The scheme is very suitable for massively parallel computation as there are no interactions among horizontal grid points. In this paper, we accelerate the Purdue Lin scheme using Intel Many Integrated Core Architecture (MIC) hardware. The Intel Xeon Phi is a high performance coprocessor consists of up to 61 cores. The Xeon Phi is connected to a CPU via the PCI Express (PICe) bus. In this paper, we will discuss in detail the code optimization issues encountered while tuning the Purdue-Lin microphysics Fortran code for Xeon Phi. In particularly, getting a good performance required utilizing multiple cores, the wide vector operations and make efficient use of memory. The results show that the optimizations improved performance of the original code on Xeon Phi 5110P by a factor of 4.2x. Furthermore, the same optimizations improved performance on Intel Xeon E5-2603 CPU by a factor of 1.2x compared to the original code.

  16. Acceleration of Cherenkov angle reconstruction with the new Intel Xeon/FPGA compute platform for the particle identification in the LHCb Upgrade

    Science.gov (United States)

    Faerber, Christian

    2017-10-01

    The LHCb experiment at the LHC will upgrade its detector by 2018/2019 to a ‘triggerless’ readout scheme, where all the readout electronics and several sub-detector parts will be replaced. The new readout electronics will be able to readout the detector at 40 MHz. This increases the data bandwidth from the detector down to the Event Filter farm to 40 TBit/s, which also has to be processed to select the interesting proton-proton collision for later storage. The architecture of such a computing farm, which can process this amount of data as efficiently as possible, is a challenging task and several compute accelerator technologies are being considered for use inside the new Event Filter farm. In the high performance computing sector more and more FPGA compute accelerators are used to improve the compute performance and reduce the power consumption (e.g. in the Microsoft Catapult project and Bing search engine). Also for the LHCb upgrade the usage of an experimental FPGA accelerated computing platform in the Event Building or in the Event Filter farm is being considered and therefore tested. This platform from Intel hosts a general CPU and a high performance FPGA linked via a high speed link which is for this platform a QPI link. On the FPGA an accelerator is implemented. The used system is a two socket platform from Intel with a Xeon CPU and an FPGA. The FPGA has cache-coherent memory access to the main memory of the server and can collaborate with the CPU. As a first step, a computing intensive algorithm to reconstruct Cherenkov angles for the LHCb RICH particle identification was successfully ported in Verilog to the Intel Xeon/FPGA platform and accelerated by a factor of 35. The same algorithm was ported to the Intel Xeon/FPGA platform with OpenCL. The implementation work and the performance will be compared. Also another FPGA accelerator the Nallatech 385 PCIe accelerator with the same Stratix V FPGA were tested for performance. The results show that the Intel

  17. [Discrimination perceived by people with a diagnosis of schizophrenic disorders. INternational study of DIscrimination and stiGma Outcomes (INDIGO): French results].

    Science.gov (United States)

    Daumerie, N; Vasseur Bacle, S; Giordana, J-Y; Bourdais Mannone, C; Caria, A; Roelandt, J-L

    2012-06-01

    The INDIGO study (INternational study of DIscrimination and stiGma Outcomes) aims at assessing the impact of schizophrenic disorders diagnosis on privacy, social and professional life, in terms of discrimination. In the general population, and even among health and social professionals, erroneous negative stereotypes (double personality, dangerosity) lead to high social distance. And this has an impact on various parts of daily life: employment, housing, compliance, self-esteem… About a tenth of the adult population suffers from mental disorders at any one time. These disorders now account for about 12% of the global impact of disability, and this will rise to 15% by the year 2020. People living with schizophrenia, for example, experience reduced social participation, whilst public images of mental illness and social reactions add a dimension of suffering, which has been described as a "second illness". Stigmatizing attitudes and discriminatory behavior among the general population against people with severe mental illness are common in all countries. Globally, little is known of effective interventions against stigma. It is clear that the negative effects of stigma can act as formidable barriers to active recovery. The INDIGO study intends to establish detailed international data on how stigma and discrimination affect the lives of people with a diagnosis of schizophrenia. The first aim of the INDIGO study is to conduct qualitative and quantitative interviews with 25 people with a diagnosis of schizophrenia in each participating site, to elicit information on how the condition affects their everyday lives, with a focus upon sites in Europe. The second is to gather data for all participating countries on the laws, policies and regulations which set a clear distinction between people with a diagnosis of mental illness and others, to establish an international profile of such discrimination. A new scale (Discrimination and Stigma Scale [DISC]), used in a face

  18. Durchführung der universitären Prüfungen im klinischen Abschnitt des Medizinstudiums nach den Leitlinien des GMA-Ausschusses Prüfungen: Eine Bestandsaufnahme der medizinischen Fakultäten in Baden-Württemberg [Implementation of assessments according to the guidelines of the GMA: A survey of the medical faculties in Baden-Württemberg

    Directory of Open Access Journals (Sweden)

    Jünger, Jana

    2010-08-01

    Full Text Available [english] With the introduction of the new medical licensing regulation [1] in 2002, a reform process was initiated nationwide that aimed to redesign medical degree programs at universities to make them more practice-oriented and to establish quality assurance in teaching. Five centers of excellence were set up at the medical schools in Baden-Württemberg that merged to form the Network for Excellence in Medical Education.The Network for Excellence in Medical Education carried out a survey among the five medical schools in Baden-Württemberg on the implementation of the requirements set down in the GMA guidelines for university-specific, high-quality assessments during the clinical phase of medical studies. The network’s next steps for improving the quality of assessments at medical schools were prioritized in order to determine the urgency of support to be given to Baden-Württemberg’s faculties of medicine in implementing the GMA requirements.It became apparent that essential parts of the requirements formulated in the guidelines had already been fulfilled or at least could be fulfilled in the near future. It was observed that establishing structured review processes during assessment preparation and in particular the follow-up presented considerable difficulties. A focus group analysis identified the following objectives for the network: supporting medical schools in their review processes; compiling a comprehensive assessment program and assessment reports with statistical analysis. Training the people responsible for assessment is another priority.The results largely correspond to those from a similar survey carried out among medical schools in Bavaria and show that organizational structures, such as those that have been established in the centers of excellence in education and assessment in Baden-Württemberg and Bavaria, can offer essential support in the quality assurance of assessment.[german] Mit der Einführung der novellierten

  19. Heat dissipation for the Intel Core i5 processor using multiwalled carbon-nanotube-based ethylene glycol

    Energy Technology Data Exchange (ETDEWEB)

    Thang, Bui Hung; Trinh, Pham Van; Quang, Le Dinh; Khoi, Phan Hong; Minh, Phan Ngoc [Vietnam Academy of Science and Technology, Ho Chi Minh CIty (Viet Nam); Huong, Nguyen Thi [Hanoi University of Science, Hanoi (Viet Nam); Vietnam National University, Hanoi (Viet Nam)

    2014-08-15

    Carbon nanotubes (CNTs) are some of the most valuable materials with high thermal conductivity. The thermal conductivity of individual multiwalled carbon nanotubes (MWCNTs) grown by using chemical vapor deposition is 600 ± 100 Wm{sup -1}K{sup -1} compared with the thermal conductivity 419 Wm{sup -1}K{sup -1} of Ag. Carbon-nanotube-based liquids - a new class of nanomaterials, have shown many interesting properties and distinctive features offering potential in heat dissipation applications for electronic devices, such as computer microprocessor, high power LED, etc. In this work, a multiwalled carbon-nanotube-based liquid was made of well-dispersed hydroxyl-functional multiwalled carbon nanotubes (MWCNT-OH) in ethylene glycol (EG)/distilled water (DW) solutions by using Tween-80 surfactant and an ultrasonication method. The concentration of MWCNT-OH in EG/DW solutions ranged from 0.1 to 1.2 gram/liter. The dispersion of the MWCNT-OH-based EG/DW solutions was evaluated by using a Zeta-Sizer analyzer. The MWCNT-OH-based EG/DW solutions were used as coolants in the liquid cooling system for the Intel Core i5 processor. The thermal dissipation efficiency and the thermal response of the system were evaluated by directly measuring the temperature of the micro-processor using the Core Temp software and the temperature sensors built inside the micro-processor. The results confirmed the advantages of CNTs in thermal dissipation systems for computer processors and other high-power electronic devices.

  20. Scalability of Parallel Spatial Direct Numerical Simulations on Intel Hypercube and IBM SP1 and SP2

    Science.gov (United States)

    Joslin, Ronald D.; Hanebutte, Ulf R.; Zubair, Mohammad

    1995-01-01

    The implementation and performance of a parallel spatial direct numerical simulation (PSDNS) approach on the Intel iPSC/860 hypercube and IBM SP1 and SP2 parallel computers is documented. Spatially evolving disturbances associated with the laminar-to-turbulent transition in boundary-layer flows are computed with the PSDNS code. The feasibility of using the PSDNS to perform transition studies on these computers is examined. The results indicate that PSDNS approach can effectively be parallelized on a distributed-memory parallel machine by remapping the distributed data structure during the course of the calculation. Scalability information is provided to estimate computational costs to match the actual costs relative to changes in the number of grid points. By increasing the number of processors, slower than linear speedups are achieved with optimized (machine-dependent library) routines. This slower than linear speedup results because the computational cost is dominated by FFT routine, which yields less than ideal speedups. By using appropriate compile options and optimized library routines on the SP1, the serial code achieves 52-56 M ops on a single node of the SP1 (45 percent of theoretical peak performance). The actual performance of the PSDNS code on the SP1 is evaluated with a "real world" simulation that consists of 1.7 million grid points. One time step of this simulation is calculated on eight nodes of the SP1 in the same time as required by a Cray Y/MP supercomputer. For the same simulation, 32-nodes of the SP1 and SP2 are required to reach the performance of a Cray C-90. A 32 node SP1 (SP2) configuration is 2.9 (4.6) times faster than a Cray Y/MP for this simulation, while the hypercube is roughly 2 times slower than the Y/MP for this application. KEY WORDS: Spatial direct numerical simulations; incompressible viscous flows; spectral methods; finite differences; parallel computing.

  1. Application of Intel Many Integrated Core (MIC) architecture to the Yonsei University planetary boundary layer scheme in Weather Research and Forecasting model

    Science.gov (United States)

    Huang, Melin; Huang, Bormin; Huang, Allen H.

    2014-10-01

    The Weather Research and Forecasting (WRF) model provided operational services worldwide in many areas and has linked to our daily activity, in particular during severe weather events. The scheme of Yonsei University (YSU) is one of planetary boundary layer (PBL) models in WRF. The PBL is responsible for vertical sub-grid-scale fluxes due to eddy transports in the whole atmospheric column, determines the flux profiles within the well-mixed boundary layer and the stable layer, and thus provide atmospheric tendencies of temperature, moisture (including clouds), and horizontal momentum in the entire atmospheric column. The YSU scheme is very suitable for massively parallel computation as there are no interactions among horizontal grid points. To accelerate the computation process of the YSU scheme, we employ Intel Many Integrated Core (MIC) Architecture as it is a multiprocessor computer structure with merits of efficient parallelization and vectorization essentials. Our results show that the MIC-based optimization improved the performance of the first version of multi-threaded code on Xeon Phi 5110P by a factor of 2.4x. Furthermore, the same CPU-based optimizations improved the performance on Intel Xeon E5-2603 by a factor of 1.6x as compared to the first version of multi-threaded code.

  2. Leitlinie für Fakultäts-interne Leistungsnachweise während des Medizinstudiums: Ein Positionspapier des GMA-Ausschusses Prüfungen und des Kompetenzzentrums Prüfungen Baden-Württemberg [

    Directory of Open Access Journals (Sweden)

    ,

    2008-02-01

    Full Text Available [english] With the implementation of a new licensing regulation for doctors in 2002 the responsibility for assessment was assigned from the German national examination board to the individual faculties, especially so for clinical subjects.39 graded reports have to be issued between the first national board examination (after 2 years of preclinical studies and the start of the internship (6th year. This new task provides special demands for assessment organization at faculty level. A number of prerequisites have to be met to guarantee adequate quality in assessment. To support faculties in meeting these requirements, guidelines were issued in cooperation with GMA assessment committee and the Baden-Württemberg competence centre for assessment in medical education. Developed on broad consensus these guidelines define quality requirements based on international standards. Their effect on quality improvement in German medical faculty’s examinations in clinical subjects is to be researched concomitantly.[german] Die neue ärztliche Approbationsordnung (ÄAppO aus dem Jahre 2002 verlagert die Prüfungsverantwortung insbesondere für den klinischen Studienabschnitt auf die Fakultäten:39 benotete Leistungsnachweise sind zwischen der ersten Staatsprüfung und praktischem Jahr zu erstellen. Diese neue Aufgabe stellt besondere Anforderungen an das fakultäre Prüfungswesen. Um eine angemessene Qualität der fakultären Prüfungen sicher zu stellen, sind eine Reihe von Voraussetzungen zu erfüllen. Die vorliegenden Leitlinien des GMA-Ausschusses Prüfungen und des Kompetenzzentrums Prüfungen des Landes Baden-Württemberg wurden erstellt, um die Fakultäten in dieser Aufgabe zu unterstützen. Die vorliegenden Leitlinien definieren die Qualitätsanforderungen unter Berücksichtigung internationaler Standards und wurden in breitem Konsens entwickelt. Ihre Wirkung im Hinblick auf die Qualitätsverbesserung der fakultären Prüfungen im klinischen

  3. Mesa de coordenadas cartesianas (x,y para la perforación de materiales por medio de un microcontrolador 8051 de intel

    Directory of Open Access Journals (Sweden)

    Omar Yesid Flórez-Prada

    2001-01-01

    Full Text Available In our environment we are surrounded by a number of electronic systems that perform automatic operations according to a number of parameters previously programmed by the operator. This paper presents the prototype of a table of two coordinates (Cartesian plane (X, Y, which uses a development system based on the 8051 microcontroller INTEL (R (computer system, making the system function sending the respective control commands to locate the tool at different points of the work area of the table, the points are previously programmed by the operator, interacting with the keyboard. To make the movements of the table (X, Y, actuator devices responsible for carrying out a linear movement that moves the tool to the specified distance are used.

  4. Simulating the Euclidean time Schroedinger equations using an Intel iPSC/860 hypercube: Application to the t-J model of high-Tc superconductivity

    International Nuclear Information System (INIS)

    Kovarik, M.D.; Barnes, T.; Tennessee Univ., Knoxville, TN

    1993-01-01

    We describe a Monte Carlo simulation of a dynamical fermion problem in two spatial dimensions on an Intel iPSC/860 hypercube. The problem studied is the determination of the dispersion relation of a dynamical hole in the t-J model of the high temperature superconductors. Since this problem involves the motion of many fermions in more than one spatial dimensions, it is representative of the class of systems that suffer from the ''minus sign problem'' of dynamical fermions which has made Monte Carlo simulation very difficult. We demonstrate that for small values of the hole hopping parameter one can extract the entire hole dispersion relation using the GRW Monte Carlo algorithm, which is a simulation of the Euclidean time Schroedinger equation, and present results on 4 x 4 and 6 x 6 lattices. Generalization to physical hopping parameter values wig only require use of an improved trial wavefunction for importance sampling

  5. SPE coupled to AAS trace determination of Cd(II) and Zn(II) in food samples using amine functionalized GMA-MMA-EGDMA terpolymer: Isotherm and kinetic studies.

    Science.gov (United States)

    Islam, Aminul; Kumar, Suneel; Zaidi, Noushi; Ahmad, Hilal

    2016-12-15

    An ethylenediamine functionalized glycidyl methacrylate (GMA) based terpolymeric chelating resin was synthesized for the separation and preconcentration of Cd(II) and Zn(II) by SPE from bread, rice and fruit juice prior to FAAS determination. The resin was characterized by FT-IR, TGA/DTA, SEM, BET analysis and EDS. Synthesized resin shows a good capacity of 53.96mgg(-1) for Cd(II) and 24.19mgg(-1) for Zn(II) at pH 8.0. Five isotherm equilibrium models were studied to explain the sorption phenomenon out of which Langmuir, Dubinin-Radushkevich, Scatchard and Temkin models were found to be the best fitted. The limit of detection (LOD) and limit of quantification (LOQ) were observed to be 1.5 and 5.1μgL(-1) for Cd and 1.2 and 4.1μgL(-1) for Zn. The reliability of the method was investigated by the analysis of SRM and the recovery of analytes from various spiked food samples. Copyright © 2016 Elsevier Ltd. All rights reserved.

  6. Estudo de alguns parâmetros básicos da soldagem GMAW com transferência por curto-circuito Evaluation of basic parameters of short-circuit GMA welding

    Directory of Open Access Journals (Sweden)

    Paulo J. Modenesi

    2011-03-01

    Full Text Available O processo de soldagem GMAW é caracterizado por uma forte interdependência de seus parâmetros operacionais e uma grande sensibilidade a variações destes. Estas características podem causar variações nas condições operacionais, dificultando o estabelecimento e a reprodução destas condições que, usualmente precisam ser verificadas pela realização de testes. Como uma forma de minimizar esta dificuldade e facilitar o entendimento da relação entre as variáveis deste processo, tem-se trabalhado no desenvolvimento de um modelo matemático capaz de simular aspectos elétricos e operacionais da soldagem GMAW. O objetivo do presente trabalho foi estudar procedimentos de determinação e fatores que afetam duas variáveis fundamentais para o desenvolvimento deste modelo (a resistividade elétrica do arame durante a soldagem e a soma das quedas de tensão anódica e catódica no arco, U AC na soldagem com transferência por curto-circuito. Os testes experimentais envolveram a deposição mecanizada de cordões emaço de baixo carbono usando arames do mesmo material com diferentes gases de proteção. Metodologias para a determinação dos parâmetros citados foram desenvolvidas com base em procedimentos similares indicados na literatura. Os detalhes destes procedimentos são avaliados, os resultados obtidos são comparados com dados da literatura e métodos para estimar a resistência elétrica entre o bico de contato e o eletrodo são apresentados. Os resultados sugerem valores para esta resistência entre 6 e 9 mΩ.GMA welding is characterized by a strong dependence between its operational parameters and a high sensitivity to small variations of those. These characteristics tend to make it harder to replicate welding conditions. It is also a barrier to welding automation and makes it necessary to perform a number of real welding tests before determining operational conditions for a given application. In order to contribute to reduce

  7. The parallel processing of EGS4 code on distributed memory scalar parallel computer:Intel Paragon XP/S15-256

    Energy Technology Data Exchange (ETDEWEB)

    Takemiya, Hiroshi; Ohta, Hirofumi; Honma, Ichirou

    1996-03-01

    The parallelization of Electro-Magnetic Cascade Monte Carlo Simulation Code, EGS4 on distributed memory scalar parallel computer: Intel Paragon XP/S15-256 is described. EGS4 has the feature that calculation time for one incident particle is quite different from each other because of the dynamic generation of secondary particles and different behavior of each particle. Granularity for parallel processing, parallel programming model and the algorithm of parallel random number generation are discussed and two kinds of method, each of which allocates particles dynamically or statically, are used for the purpose of realizing high speed parallel processing of this code. Among four problems chosen for performance evaluation, the speedup factors for three problems have been attained to nearly 100 times with 128 processor. It has been found that when both the calculation time for each incident particles and its dispersion are large, it is preferable to use dynamic particle allocation method which can average the load for each processor. And it has also been found that when they are small, it is preferable to use static particle allocation method which reduces the communication overhead. Moreover, it is pointed out that to get the result accurately, it is necessary to use double precision variables in EGS4 code. Finally, the workflow of program parallelization is analyzed and tools for program parallelization through the experience of the EGS4 parallelization are discussed. (author).

  8. A Monte Carlo study of the ''minus sign problem'' in the t-J model using an intel IPSC/860 hypercube

    International Nuclear Information System (INIS)

    Kovarik, M.D.; Barnes, T.; Tennessee Univ., Knoxville, TN

    1993-01-01

    We describe a Monte Carlo simulation of the 2-dimensional t-J model on an Intel iPSC/860 hypercube. The problem studied is the determination of the dispersion relation of a dynamical hole in the t-J model of the high temperature superconductors. Since this problem involves the motion of many fermions in more than one spatial dimensions, it is representative of the class of systems that suffer from the ''minus sign problem'' of dynamical fermions which has made Monte Carlo simulation very difficult. We demonstrate that for small values of the hole hopping parameter one can extract the entire hole dispersion relation using the GRW Monte Carlo algorithm, which is a simulation of the Euclidean time Schroedinger equation, and present results on 4 x 4 and 6 x 6 lattices. We demonstrate that a qualitative picture at higher hopping parameters may be found by extrapolating weak hopping results where the minus sign problem is less severe. Generalization to physical hopping parameter values will only require use of an improved trial wavefunction for importance sampling

  9. Laser-GMA Hybrid Pipe Welding System

    National Research Council Canada - National Science Library

    Reutzel, Edward W; Kern, Ludwig; Sullivan, Michael J; Tressler, Jay F; Avalos, Juan

    2007-01-01

    The combination of laser welding with conventional gas metal arc welding technology offers substantial increases in production rate of joining pipe through single-pass joining compared to multi-pass...

  10. Laser-GMA Hybrid Pipe Welding System

    Science.gov (United States)

    2007-11-01

    Investigation of varying laser power. The welded pipe is shown, with close -ups of the rootside reinforcement and macro sections...68 Figure 44. Investigation of varying laser stand-off. The welded pipe is shown, along with close -ups of backside...conventional beveled joints. With appropriate joint configuration and preparation, deep keyhole penetration provided by the laser and additional filler

  11. TH-A-19A-08: Intel Xeon Phi Implementation of a Fast Multi-Purpose Monte Carlo Simulation for Proton Therapy

    Energy Technology Data Exchange (ETDEWEB)

    Souris, K; Lee, J; Sterpin, E [Universite catholique de Louvain, Brussels (Belgium)

    2014-06-15

    Purpose: Recent studies have demonstrated the capability of graphics processing units (GPUs) to compute dose distributions using Monte Carlo (MC) methods within clinical time constraints. However, GPUs have a rigid vectorial architecture that favors the implementation of simplified particle transport algorithms, adapted to specific tasks. Our new, fast, and multipurpose MC code, named MCsquare, runs on Intel Xeon Phi coprocessors. This technology offers 60 independent cores, and therefore more flexibility to implement fast and yet generic MC functionalities, such as prompt gamma simulations. Methods: MCsquare implements several models and hence allows users to make their own tradeoff between speed and accuracy. A 200 MeV proton beam is simulated in a heterogeneous phantom using Geant4 and two configurations of MCsquare. The first one is the most conservative and accurate. The method of fictitious interactions handles the interfaces and secondary charged particles emitted in nuclear interactions are fully simulated. The second, faster configuration simplifies interface crossings and simulates only secondary protons after nuclear interaction events. Integral depth-dose and transversal profiles are compared to those of Geant4. Moreover, the production profile of prompt gammas is compared to PENH results. Results: Integral depth dose and transversal profiles computed by MCsquare and Geant4 are within 3%. The production of secondaries from nuclear interactions is slightly inaccurate at interfaces for the fastest configuration of MCsquare but this is unlikely to have any clinical impact. The computation time varies between 90 seconds for the most conservative settings to merely 59 seconds in the fastest configuration. Finally prompt gamma profiles are also in very good agreement with PENH results. Conclusion: Our new, fast, and multi-purpose Monte Carlo code simulates prompt gammas and calculates dose distributions in less than a minute, which complies with clinical time

  12. TH-A-19A-08: Intel Xeon Phi Implementation of a Fast Multi-Purpose Monte Carlo Simulation for Proton Therapy

    International Nuclear Information System (INIS)

    Souris, K; Lee, J; Sterpin, E

    2014-01-01

    Purpose: Recent studies have demonstrated the capability of graphics processing units (GPUs) to compute dose distributions using Monte Carlo (MC) methods within clinical time constraints. However, GPUs have a rigid vectorial architecture that favors the implementation of simplified particle transport algorithms, adapted to specific tasks. Our new, fast, and multipurpose MC code, named MCsquare, runs on Intel Xeon Phi coprocessors. This technology offers 60 independent cores, and therefore more flexibility to implement fast and yet generic MC functionalities, such as prompt gamma simulations. Methods: MCsquare implements several models and hence allows users to make their own tradeoff between speed and accuracy. A 200 MeV proton beam is simulated in a heterogeneous phantom using Geant4 and two configurations of MCsquare. The first one is the most conservative and accurate. The method of fictitious interactions handles the interfaces and secondary charged particles emitted in nuclear interactions are fully simulated. The second, faster configuration simplifies interface crossings and simulates only secondary protons after nuclear interaction events. Integral depth-dose and transversal profiles are compared to those of Geant4. Moreover, the production profile of prompt gammas is compared to PENH results. Results: Integral depth dose and transversal profiles computed by MCsquare and Geant4 are within 3%. The production of secondaries from nuclear interactions is slightly inaccurate at interfaces for the fastest configuration of MCsquare but this is unlikely to have any clinical impact. The computation time varies between 90 seconds for the most conservative settings to merely 59 seconds in the fastest configuration. Finally prompt gamma profiles are also in very good agreement with PENH results. Conclusion: Our new, fast, and multi-purpose Monte Carlo code simulates prompt gammas and calculates dose distributions in less than a minute, which complies with clinical time

  13. Comparison of two accelerators for Monte Carlo radiation transport calculations, Nvidia Tesla M2090 GPU and Intel Xeon Phi 5110p coprocessor: A case study for X-ray CT imaging dose calculation

    International Nuclear Information System (INIS)

    Liu, T.; Xu, X.G.; Carothers, C.D.

    2015-01-01

    Highlights: • A new Monte Carlo photon transport code ARCHER-CT for CT dose calculations is developed to execute on the GPU and coprocessor. • ARCHER-CT is verified against MCNP. • The GPU code on an Nvidia M2090 GPU is 5.15–5.81 times faster than the parallel CPU code on an Intel X5650 6-core CPU. • The coprocessor code on an Intel Xeon Phi 5110p coprocessor is 3.30–3.38 times faster than the CPU code. - Abstract: Hardware accelerators are currently becoming increasingly important in boosting high performance computing systems. In this study, we tested the performance of two accelerator models, Nvidia Tesla M2090 GPU and Intel Xeon Phi 5110p coprocessor, using a new Monte Carlo photon transport package called ARCHER-CT we have developed for fast CT imaging dose calculation. The package contains three components, ARCHER-CT CPU , ARCHER-CT GPU and ARCHER-CT COP designed to be run on the multi-core CPU, GPU and coprocessor architectures respectively. A detailed GE LightSpeed Multi-Detector Computed Tomography (MDCT) scanner model and a family of voxel patient phantoms are included in the code to calculate absorbed dose to radiosensitive organs under user-specified scan protocols. The results from ARCHER agree well with those from the production code Monte Carlo N-Particle eXtended (MCNPX). It is found that all the code components are significantly faster than the parallel MCNPX run on 12 MPI processes, and that the GPU and coprocessor codes are 5.15–5.81 and 3.30–3.38 times faster than the parallel ARCHER-CT CPU , respectively. The M2090 GPU performs better than the 5110p coprocessor in our specific test. Besides, the heterogeneous computation mode in which the CPU and the hardware accelerator work concurrently can increase the overall performance by 13–18%

  14. Parallel solution of the time-dependent Ginzburg-Landau equations and other experiences using BlockComm-Chameleon and PCN on the IBM SP, Intel iPSC/860, and clusters of workstations

    International Nuclear Information System (INIS)

    Coskun, E.

    1995-09-01

    Time-dependent Ginzburg-Landau (TDGL) equations are considered for modeling a thin-film finite size superconductor placed under magnetic field. The problem then leads to the use of so-called natural boundary conditions. Computational domain is partitioned into subdomains and bond variables are used in obtaining the corresponding discrete system of equations. An efficient time-differencing method based on the Forward Euler method is developed. Finally, a variable strength magnetic field resulting in a vortex motion in Type II High T c superconducting films is introduced. The authors tackled the problem using two different state-of-the-art parallel computing tools: BlockComm/Chameleon and PCN. They had access to two high-performance distributed memory supercomputers: the Intel iPSC/860 and IBM SP1. They also tested the codes using, as a parallel computing environment, a cluster of Sun Sparc workstations

  15. Comparison of 2 accelerators of Monte Carlo radiation transport calculations, NVIDIA tesla M2090 GPU and Intel Xeon Phi 5110p coprocessor: a case study for X-ray CT Imaging Dose calculation

    International Nuclear Information System (INIS)

    Liu, T.; Xu, X.G.; Carothers, C.D.

    2013-01-01

    Hardware accelerators are currently becoming increasingly important in boosting high performance computing systems. In this study, we tested the performance of two accelerator models, NVIDIA Tesla M2090 GPU and Intel Xeon Phi 5110p coprocessor, using a new Monte Carlo photon transport package called ARCHER-CT we have developed for fast CT imaging dose calculation. The package contains three code variants, ARCHER-CT(CPU), ARCHER-CT(GPU) and ARCHER-CT(COP) to run in parallel on the multi-core CPU, GPU and coprocessor architectures respectively. A detailed GE LightSpeed Multi-Detector Computed Tomography (MDCT) scanner model and a family of voxel patient phantoms were included in the code to calculate absorbed dose to radiosensitive organs under specified scan protocols. The results from ARCHER agreed well with those from the production code Monte Carlo N-Particle eXtended (MCNPX). It was found that all the code variants were significantly faster than the parallel MCNPX running on 12 MPI processes, and that the GPU and coprocessor performed equally well, being 2.89-4.49 and 3.01-3.23 times faster than the parallel ARCHER-CT(CPU) running with 12 hyper-threads. (authors)

  16. Implementación a nivel universitario del curso INTEL educar para el futuro: sistematización de la experiencia en la Facultad de Educación de la Universidad de Costa Rica

    Directory of Open Access Journals (Sweden)

    Flora Eugenia Salas Madriz

    2003-01-01

    Full Text Available La Facultad de Educación de la Universidad de Costa Rica, consciente del impacto e importancia que están adquiriendo las tecnologías educativas digitales en el ámbito educativo a nivel nacional y mundial, ha creado el Programa Tecnologías Educativas Avanzadas (PROTEA para el desarrollo y la investigación en este campo. En este artículo se sistematiza la experiencia de nueve docentes de la Universidad de Costa Rica, que colaboraron en la adecuación para el nivel universitario del curso Intel Educar para el Futuro, impartido por la Fundación Omar Dengo. Éste está orientado a educadores de primaria y secundaria, y su propósito es poner a disposición de los educadores las herramientas del Office® de Microsoft ® para desarrollar los procesos de enseñanza. Debido a las diferencias de fondo y forma entre la educación primaria y secundaria, y la universitaria, se hizo necesario revisar el manual y la metodología a fin de adaptarlos a las necesidades de la docencia universitaria y de la formación de formadores. En este sentido, la experiencia y colaboración de los docentes participantes fue determinante para lograr que el curso alcance hoy sus objetivos de poner estas herramientas al servicio de la docencia universitaria

  17. Comparison of Two Accelerators for Monte Carlo Radiation Transport Calculations, NVIDIA Tesla M2090 GPU and Intel Xeon Phi 5110p Coprocessor: A Case Study for X-ray CT Imaging Dose Calculation

    Science.gov (United States)

    Liu, Tianyu; Xu, X. George; Carothers, Christopher D.

    2014-06-01

    Hardware accelerators are currently becoming increasingly important in boosting high performance computing sys- tems. In this study, we tested the performance of two accelerator models, NVIDIA Tesla M2090 GPU and Intel Xeon Phi 5110p coprocessor, using a new Monte Carlo photon transport package called ARCHER-CT we have developed for fast CT imaging dose calculation. The package contains three code variants, ARCHER - CTCPU, ARCHER - CTGPU and ARCHER - CTCOP to run in parallel on the multi-core CPU, GPU and coprocessor architectures respectively. A detailed GE LightSpeed Multi-Detector Computed Tomography (MDCT) scanner model and a family of voxel patient phantoms were included in the code to calculate absorbed dose to radiosensitive organs under specified scan protocols. The results from ARCHER agreed well with those from the production code Monte Carlo N-Particle eXtended (MCNPX). It was found that all the code variants were significantly faster than the parallel MCNPX running on 12 MPI processes, and that the GPU and coprocessor performed equally well, being 2.89~4.49 and 3.01~3.23 times faster than the parallel ARCHER - CTCPU running with 12 hyperthreads.

  18. The Intelence aNd pRezista Once A Day Study (INROADS): a multicentre, single-arm, open-label study of etravirine and darunavir/ritonavir as dual therapy in HIV-1-infected early treatment-experienced subjects.

    Science.gov (United States)

    Ruane, P J; Brinson, C; Ramgopal, M; Ryan, R; Coate, B; Cho, M; Kakuda, T N; Anderson, D

    2015-05-01

    Following antiretroviral therapy failure, patients are often treated with a three-drug regimen that includes two nucleoside/tide reverse transcriptase inhibitors [N(t)RTIs]. An alternative two-drug nucleoside-sparing regimen may decrease the pill burden and drug toxicities associated with the use of N(t)RTIs. The Intelence aNd pRezista Once A Day Study (INROADS; NCT01199939) evaluated the nucleoside-sparing regimen of etravirine 400 mg with darunavir/ritonavir 800/100 mg once-daily in HIV-1-infected treatment-experienced subjects or treatment-naïve subjects with transmitted resistance. In this exploratory phase 2b, single-arm, open-label, multicentre, 48-week study, the primary endpoint was the proportion of subjects who achieved HIV-1 RNA treatment-experienced subjects or treatment-naïve subjects with transmitted resistance was virologically efficacious and well tolerated. © 2014 British HIV Association.

  19. A Neural Network Approach for GMA Butt Joint Welding

    DEFF Research Database (Denmark)

    Christensen, Kim Hardam; Sørensen, Torben

    2003-01-01

    This paper describes the application of the neural network technology for gas metal arc welding (GMAW) control. A system has been developed for modeling and online adjustment of welding parameters, appropriate to guarantee a certain degree of quality in the field of butt joint welding with full...... penetration, when the gap width is varying during the welding process. The process modeling to facilitate the mapping from joint geometry and reference weld quality to significant welding parameters has been based on a multi-layer feed-forward network. The Levenberg-Marquardt algorithm for non-linear least...

  20. Microstructural Characterization of HSLA-100 GMA-Weldments

    Science.gov (United States)

    1987-09-01

    Intermeiate Oxygen Regime ----------- 66 D.) Schematic CCT Diagram - --------------- 66 9 ACKNOWLEDGEMENTS I wish to express my appreciation to my thesis...have been observed in this research [review Figures 31 (a), (b) and 35 (a)]. Figure 38 (d) shows a schematic CCT diagram reported by Glover (Ref. 5) and...Regime B.) High Ox. gen Regime C. )Interme late Oxygen Regime D.1 Schematic CCT Diagram 66 LIST OF REFERENCES 1. Anderson, T.L., Hyatt J A West, J.C

  1. Structure/property relationships in multipass GMA welding of beryllium.

    Energy Technology Data Exchange (ETDEWEB)

    Hochanadel, P. W. (Patrick W.); Hults, W. L. (William L.); Thoma, D. J. (Dan J.); Dave, V. R. (Vivek R.); Kelly, A. M. (Anna Marie); Pappin, P. A. (Pallas A.); Cola, M. J. (Mark J.); Burgardt, P. (Paul)

    2001-01-01

    Beryllium is an interesting metal that has a strength to weight ratio six times that of steel. Because of its unique mechanical properties, beryllium is used in aerospace applications such as satellites. In addition, beryllium is also used in x-ray windows because it is nearly transparent to x-rays. Joining of beryllium has been studied for decades (Ref.l). Typically joining processes include braze-welding (either with gas tungsten arc or gas metal arc), soldering, brazing, and electron beam welding. Cracking which resulted from electron beam welding was recently studied to provide structure/property relationships in autogenous welds (Ref. 2). Braze-welding utilizes a welding arc to melt filler, and only a small amount of base metal is melted and incorporated into the weld pool. Very little has been done to characterize the braze-weld in terms of the structure/property relationships, especially with reference to multipass welding. Thus, this investigation was undertaken to evaluate the effects of multiple passes on microstructure, weld metal composition, and resulting material properties for beryllium welded with aluminum-silicon filler metal.

  2. Quality assurance and control for robotic GMA welding

    International Nuclear Information System (INIS)

    Xie Max X.

    1992-01-01

    A quality assurance (QA) model has been developed. This model systematically considers the relevant activities before, during and after the welding operations with respect to quality. Efficient quality assurance requires that the functionality of the present robotic welding systems needs to be increased and that the knowledge of the personnel involved in the design and production needs to be improved. The collaboration between different departments and personnel needs also to be improved. The procedure specification aspects have been studied and a method for the determination of optimal welding parameters is presented with regards to process stability, quality requirements and productivity. A main productivity problem of robotic welding systems for small series production is due to the time spent on the specification of welding procedures. In order to improve the efficiency, expert systems technology has been studied and applied to automatically generate optimal welding procedures. An objective method for the assessment of process stability has been developed, based upon the analysis of the electrical signals of welding arcs. Furthermore, a method has been developed to monitor the process stability. It is found that it is possible to identify the causes of the disturbance of process stability and to predict the weld quality characteristics based on the analysis of the electrical signals. Though quality is formed during the welding operation, the diagnosis of the causes of quality disturbances is important for the prevention of quality problems of subsequent welds and has been discussed. To assist the operators, expert systems technology is also applied. Further work should be directed to the integration of various QA functions in the robotic arc welding system so that both quality and productivity aspects of the system ban be further improved. (au)

  3. A Neural Network Approach for GMA Butt Joint Welding

    DEFF Research Database (Denmark)

    Christensen, Kim Hardam; Sørensen, Torben

    2003-01-01

    penetration, when the gap width is varying during the welding process. The process modeling to facilitate the mapping from joint geometry and reference weld quality to significant welding parameters has been based on a multi-layer feed-forward network. The Levenberg-Marquardt algorithm for non-linear least......This paper describes the application of the neural network technology for gas metal arc welding (GMAW) control. A system has been developed for modeling and online adjustment of welding parameters, appropriate to guarantee a certain degree of quality in the field of butt joint welding with full...

  4. Control of GMA Butt Joint Welding Based on Neural Networks

    DEFF Research Database (Denmark)

    Christensen, Kim Hardam; Sørensen, Torben

    2004-01-01

    This paper presents results from an experimentally based research on Gas Metal Arc Welding (GMAW), controlled by the artificial neural network (ANN) technology. A system has been developed for modeling and online adjustment of welding parameters, appropriate to guarantee a high degree of quality......-linear least square error minimization, has been used with the back-propagation algorithm for training the network, while a Bayesian regularization technique has been successfully applied for minimizing the risk of inexpedient over-training....

  5. Internet of Things with Intel Galileo

    CERN Document Server

    de Sousa, Miguel

    2015-01-01

    This book employs an incremental, step-by-step approach to get you familiarized with everything from the basic terms, board components, and development environments to developing real projects. Each project will demonstrate how to use specific board components and tools. Both Galileo and Galileo Gen 2 are covered in this book.

  6. Wafer of Intel Pentium 4 Prescott Chips

    CERN Multimedia

    Silicon wafer with hundreds of Penryn cores (microprocessor). There are around four times as many Prescott chips can be made per wafer than with the previous generation of Northwood-core Pentium 4 processors. It is faster and cheaper.

  7. La reforma projectada de la Comissió de Propietat Intel·lectual del Ministeri de Cultura i el “procediment per al restabliment de la legalitat”, la instrucció i resolució del qual es vol atribuir a la seva proposada Secció Segona.

    Directory of Open Access Journals (Sweden)

    Pablo Ferrándiz

    2010-07-01

    Full Text Available La disposició final segona del Projecte de llei d'economia sostenible que el Govern ha presentat al Congrés dels Diputats projecta crear una nova comissió de propietat intel·lectual al si del Ministeri de Cultura, que passarà a estar integrada per dues seccions: la Secció Primera i la Secció Segona. En particular, a la Secció Segona es vol atribuir la instrucció i resolució d'un nou procediment administratiu, anomenat per al restabliment de la legalitat, el qual podrà finalitzar amb l'adopció de mesures de restricció a la prestació de serveis de la societat de la informació, com ara la interrupció del servei o la retirada de les dades, quan vulnerin drets de propietat intel·lectual, però sempre que el seu responsable ho dugui a terme amb ànim de lucre, directe o indirecte, o hagi causat o sigui susceptible de causar un dany patrimonial. Encara que l'execució de tals mesures requerirà l'autorització judicial prèvia mitjançant una interlocutòria, l'òrgan competent per a la qual és el Jutjat Central Contenciós Administratiu de l'Audiència Nacional, l'atribució a una administració pública de competències per a resoldre controvèrsies o conflictes entre particulars, sobre drets (els de propietat intel·lectual de naturalesa estrictament privada (això és, uns drets, encara que sigui especial, de propietat, planteja no pocs interrogants passant l'assumpte pel tamís del principi de separació de poders que consagra l'article 117 de la Constitució i qüestiona la neutralitat de l'Administració pública, ja que no es justifica degudament en el projecte de llei que amb la seva actuació serveix, com exigeix l'article 103 del text fonamental, amb objectivitat, als interessos generals.

  8. Real-time operating system for selected Intel processors

    Science.gov (United States)

    Pool, W. R.

    1980-01-01

    The rationale for system development is given along with reasons for not using vendor supplied operating systems. Although many system design and performance goals were dictated by problems with vendor supplied systems, other goals surfaced as a result of a design for a custom system able to span multiple projects. System development and management problems and areas that required redesign or major code changes for system implementation are examined as well as the relative successes of the initial projects. A generic description of the actual project is provided and the ongoing support requirements and future plans are discussed.

  9. A fast random number generator for the Intel Paragon supercomputer

    Science.gov (United States)

    Gutbrod, F.

    1995-06-01

    A pseudo-random number generator is presented which makes optimal use of the architecture of the i860-microprocessor and which is expected to have a very long period. It is therefore a good candidate for use on the parallel supercomputer Paragon XP. In the assembler version, it needs 6.4 cycles for a real∗4 random number. There is a FORTRAN routine which yields identical numbers up to rare and minor rounding discrepancies, and it needs 28 cycles. The FORTRAN performance on other microprocessors is somewhat better. Arguments for the quality of the generator and some numerical tests are given.

  10. Lexicografia i intel·ligència artificial

    Directory of Open Access Journals (Sweden)

    Ramon Cerdà Massó

    2015-10-01

    Full Text Available Unlike most of traditional approaches to grammar, today's formal and computational models make use of the lexicon as an essential part of the whole system. Differences between current theoretical and computational models are more and more insignificant albeit the latter are perhaps still characterized by yielding full priority to minimalist solutions over more abstract considerations such as exhaustivity or formal elegance. The paper introduces some strategies in linguistic computation for natural language processing (NLP according to a typology based on functional complexity and describing in every case the scope and the role performed by the dictionary: pattern matching, semàntic grammars, syntactic parsers, augmented transition networks, unification formalisms, case frame grammars, etc. It ends with an exploration into lexicographically oriented procedures of conceptual dependency, which are found beyond the NLP, deeply within the domain of artificial intelligence.

  11. Small range logarithm calculation on Intel Quartus II Verilog

    Science.gov (United States)

    Mustapha, Muhazam; Mokhtar, Anis Shahida; Ahmad, Azfar Asyrafie

    2018-02-01

    Logarithm function is the inverse of exponential function. This paper implement power series of natural logarithm function using Verilog HDL in Quartus II. The mode of design used is RTL in order to decrease the number of megafunctions. The simulations were done to determine the precision and number of LEs used so that the output calculated accurately. It is found that the accuracy of the system only valid for the range of 1 to e.

  12. Intel vahetab Pentiumi uute protsessorite vastu / Kuldar Kullasepp

    Index Scriptorium Estoniae

    Kullasepp, Kuldar, 1980-

    2006-01-01

    Vt. ka Postimees : na russkom jazõke 19. juuni, lk. 14. Maailma suurim protsessoritootja kavatseb aasta jooksul pea täielikult üle minna mitme tuumaga protsessorite tootmisele, rääkis Inteli firma Euroopa turundusjuht Alex Roessler

  13. Adaptación de Neurite a Intel Xeon Phi

    OpenAIRE

    Yanguas Martín, Jorge Pablo

    2016-01-01

    Hoy en día, podremos comprobar que todos los súper computadores que se utilizan alrededor del mundo aprovechan numerosos procesadores en paralelo con la intención de conseguir el mejor rendimiento posible. La lista de los diez súper computadores más potentes del mundo de noviembre de 2015 utilizan esta filosofía.Con la particularidad de que dos de ellos utilizan a modo de coprocesador las GPUs K20x de Nvidia y otros dos, uno de ellos siendo actualmente el súper computador má...

  14. Evaluation of the Intel Westmere-EP server processor

    CERN Document Server

    Jarp, S; Leduc, J; Nowak, A; CERN. Geneva. IT Department

    2010-01-01

    In this paper we report on a set of benchmark results recently obtained by CERN openlab when comparing the 6-core “Westmere-EP” processor with Intel’s previous generation of the same microarchitecture, the “Nehalem-EP”. The former is produced in a new 32nm process, the latter in 45nm. Both platforms are dual-socket servers. Multiple benchmarks were used to get a good understanding of the performance of the new processor. We used both industry-standard benchmarks, such as SPEC2006, and specific High Energy Physics benchmarks, representing both simulation of physics detectors and data analysis of physics events. Before summarizing the results we must stress the fact that benchmarking of modern processors is a very complex affair. One has to control (at least) the following features: processor frequency, overclocking via Turbo mode, the number of physical cores in use, the use of logical cores via Simultaneous Multi-Threading (SMT), the cache sizes available, the memory configuration installed, as well...

  15. Virtual Reality Presentation of Moment Tensor Analysis by SiGMA

    International Nuclear Information System (INIS)

    Ohtsu, Masayasu; Shigeishi, Mitsuhiro

    2003-01-01

    Nucleation of a crack is readily defected by acoustic emission (AE) method. One powerful technique for AE waveform analysis has been developed as SiGMh (Simplified Greens functions for Moment tensor Analysis), as crack kinematics of locations, types and orientations are quantitatively determined. Because these kinematical outcomes are obtained as three-dimensional (3-D) locations and vectors, 3-D visualization is definitely desirable. To this end, the visualization system has been developed by using VRML (Virtual Reality Modeling Language). As an application, failure protest of a reinforced concrete beam is discussed

  16. Optimization of arc-start performance by wire-feeding control for GMA welding

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Jong Gu; Ryu, Gyeong Su; Rhee, Se Hun [Hanyang University, Seoul (Korea, Republic of); Kim, Dong Cheol; Kang, Mun Jin [Korea Institute of Industrial Technology, Incheon (Korea, Republic of); Park, Young Whan [Pukyong National University, Busan (Korea, Republic of)

    2013-02-15

    The wire feeding system for gas metal arc welding usually consists of a wire feeder and a torch. In many industries, the distance between the wire feeder and the torch is generally 3 m to 5 m. In a conventional wire feeder, a direct current (DC) motor is used for wire feeding. However, a significant problem with this system is the impossibility of feedback control because of inner or outer impedance. In this paper, a digital wire feeder was developed by using a DC encoder motor and a push-pull torch. An optimized wire-feeding system was also developed by experiment. The welding process was observed using a high-speed camera. The resulting wire-feeding system exhibits low spatter generation and arc stability.

  17. Disseny d'una arquitectura IoT per a ciutats intel·ligents i desenvolupament d'un servei d'enllumenat intel·ligent

    OpenAIRE

    Hernández Jordán, Ana Leticia

    2013-01-01

    [ANGLÈS] Smart cities have been recently pointed out by experts an emerging market with enormous potential, which is expected to drive the digital economy forward in the coming years. Nowadays, cities hold half of the global population, consume 75% of the world´s energy resources and emit 80% of the carbon that is harming the environment. Making a city “smart” is emerging as a strategy to mitigate the problems generated by the urban population growth and rapid urbanization. In that way, by us...

  18. SCIPHI - Score-P and Cube Extensions for Intel Xeon Phi

    OpenAIRE

    Feld, Christian; Schlütter, Marc; Saviankou, Pavel; Knobloch, Michael; Mohr, Bernd

    2017-01-01

    The KNL processors offers unique features concerning memory hierarchy and vectorization capabilities. To improve tool support within these two areas, we present extensions to the Score-P measurement system and the Cube report explorer.KNL introduced a new memory architecture, utilizing MCDRAM and DDR. To help the user in the decision where to place data structures, we record a MCDRAM candidate metric. In addition we track all MCDRAM allocations through the hbwmalloc API, providing memory metr...

  19. Social and Intel lectual Trends at Rhodes in the Early Sixties and ...

    African Journals Online (AJOL)

    canberry

    When I arrived at Rhodes in 1962, the only graduates I had ever met were doctors .... expect me to fail at university, were aston ished at the end of my first year to find .... Irving was a socialist and a deter mined one, but his best friend was fellow.

  20. Object identification with deep learning using Intel DAAL on Knights Landing processor [Vidyo

    CERN Multimedia

    CERN. Geneva

    2017-01-01

    The problem of object recognition is computationally expensive, especially when large amounts of data is involved. Recently, techniques in deep neural networks (DNN) - including convolutional neural networks and residual neural networks - have shown great recognition accuracy compared to traditional methods (artificial neural networks, decision tress, etc.). However, experience reveals that there are still a number of factors that limit scientists from deriving the full performance benefits of large, DNNs. We summarize these challenges as follows: (1) large number of hyperparameters that have to be tuned against the DNN during training phase, leading to several data re-computations over a large design-space, (2) the share volume of data used for training, resulting in prolonged training time, (3) how to effectively utilize underlying hardware (compute, network and storage) to achieve maximum performance during this training phase. In this presentation, we discuss a cross-layer perspective into realizing effic...

  1. Accelerating 3D Elastic Wave Equations on Knights Landing based Intel Xeon Phi processors

    Science.gov (United States)

    Sourouri, Mohammed; Birger Raknes, Espen

    2017-04-01

    In advanced imaging methods like reverse-time migration (RTM) and full waveform inversion (FWI) the elastic wave equation (EWE) is numerically solved many times to create the seismic image or the elastic parameter model update. Thus, it is essential to optimize the solution time for solving the EWE as this will have a major impact on the total computational cost in running RTM or FWI. From a computational point of view applications implementing EWEs are associated with two major challenges. The first challenge is the amount of memory-bound computations involved, while the second challenge is the execution of such computations over very large datasets. So far, multi-core processors have not been able to tackle these two challenges, which eventually led to the adoption of accelerators such as Graphics Processing Units (GPUs). Compared to conventional CPUs, GPUs are densely populated with many floating-point units and fast memory, a type of architecture that has proven to map well to many scientific computations. Despite its architectural advantages, full-scale adoption of accelerators has yet to materialize. First, accelerators require a significant programming effort imposed by programming models such as CUDA or OpenCL. Second, accelerators come with a limited amount of memory, which also require explicit data transfers between the CPU and the accelerator over the slow PCI bus. The second generation of the Xeon Phi processor based on the Knights Landing (KNL) architecture, promises the computational capabilities of an accelerator but require the same programming effort as traditional multi-core processors. The high computational performance is realized through many integrated cores (number of cores and tiles and memory varies with the model) organized in tiles that are connected via a 2D mesh based interconnect. In contrary to accelerators, KNL is a self-hosted system, meaning explicit data transfers over the PCI bus are no longer required. However, like most accelerators, KNL sports a memory subsystem consisting of low-level caches and 16GB of high-bandwidth MCDRAM memory. For capacity computing, up to 400GB of conventional DDR4 memory is provided. Such a strict hierarchical memory layout means that data locality is imperative if the true potential of this product is to be harnessed. In this work, we study a series of optimizations specifically targeting KNL for our EWE based application to reduce the time-to-solution time for the following 3D model sizes in grid points: 1283, 2563 and 5123. We compare the results with an optimized version for multi-core CPUs running on a dual-socket Xeon E5 2680v3 system using OpenMP. Our initial naive implementation on the KNL is roughly 20% faster than the multi-core version, but by using only one thread per core and careful memory placement using the memkind library, we could achieve higher speedups. Additionally, by using the MCDRAM as cache for problem sizes that are smaller than 16 GB further performance improvements were unlocked. Depending on the problem size, our overall results indicate that the KNL based system is approximately 2.2x faster than the 24-core Xeon E5 2680v3 system, with only modest changes to the code.

  2. Modeling high-temperature superconductors and metallic alloys on the Intel iPSC/860

    International Nuclear Information System (INIS)

    Geist, G.A.; Peyton, B.W.; Shelton, W.A.; Stocks, G.M.

    1990-01-01

    Oak Ridge National Laboratory has embarked on several computational grand Challenges, which require the close cooperation of physicists, mathematicians, and computer scientists. One of these projects is the determination of the material properties of alloys form first principles and, in particular, the electronic structure of high-temperature superconductors. The physical basis for high Tc superconductivity is not well understood. The design of materials with higher critical temperatures and the ability to carry higher current densities can be greatly facilitated by the modeling and detailed study of the electronic structure of existing superconductors. This paper describes the progress to data on this project. We include a description of a self-consistent KKR-CPA method, parallelization of the model, and the incorporation of a dynamic load balancing scheme into the algorithm. We also describe the development and performance of a consolidated KKR-CPA code capable of running on CRAYs, workstations, and several parallel computers without source code modification

  3. Parallel Application Performance on Two Generations of Intel Xeon HPC Platforms

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Christopher H.; Long, Hai; Sides, Scott; Vaidhynathan, Deepthi; Jones, Wesley

    2015-10-15

    Two next-generation node configurations hosting the Haswell microarchitecture were tested with a suite of microbenchmarks and application examples, and compared with a current Ivy Bridge production node on NREL" tm s Peregrine high-performance computing cluster. A primary conclusion from this study is that the additional cores are of little value to individual task performance--limitations to application parallelism, or resource contention among concurrently running but independent tasks, limits effective utilization of these added cores. Hyperthreading generally impacts throughput negatively, but can improve performance in the absence of detailed attention to runtime workflow configuration. The observations offer some guidance to procurement of future HPC systems at NREL. First, raw core count must be balanced with available resources, particularly memory bandwidth. Balance-of-system will determine value more than processor capability alone. Second, hyperthreading continues to be largely irrelevant to the workloads that are commonly seen, and were tested here, at NREL. Finally, perhaps the most impactful enhancement to productivity might occur through enabling multiple concurrent jobs per node. Given the right type and size of workload, more may be achieved by doing many slow things at once, than fast things in order.

  4. Quinze anys. Una biografia intel·lectual col·lectiva

    OpenAIRE

    Casassas i Ymbert, Jordi

    2004-01-01

    Jordi Casassas, academic coordinator of the GEHCI (Group of Studies on the History of Culture and Intellectuals), offers a brief approach to the history of this research group, which began its activity in 1989. He exposes the main projects of its members and the works published throughout this time.

  5. Air Commando Intel: Optimizing Specialization Training for Air Force Special Operations Command Intelligence Officers

    Science.gov (United States)

    2011-12-01

    15 2. Managing Careers by Core Competencies ......................................15 D. GLASS CEILINGS ...Transforming the Force: Past, Present & Future,” Slide presentation, Washington, D.C., October 28, 2002, 5. 38 Ibid. 17 D. GLASS CEILINGS Getting AF...Agency Support to PR MSN Mission Planning SOF Mission Planning Exercise/Organization, Case Studies (Somalia/ Lebanon ), HUMINT case study SYS Systems

  6. Porting of the DBCSR library for Sparse Matrix-Matrix Multiplications to Intel Xeon Phi systems

    OpenAIRE

    Bethune, Iain; Gloess, Andeas; Hutter, Juerg; Lazzaro, Alfio; Pabst, Hans; Reid, Fiona

    2017-01-01

    Multiplication of two sparse matrices is a key operation in the simulation of the electronic structure of systems containing thousands of atoms and electrons. The highly optimized sparse linear algebra library DBCSR (Distributed Block Compressed Sparse Row) has been specifically designed to efficiently perform such sparse matrix-matrix multiplications. This library is the basic building block for linear scaling electronic structure theory and low scaling correlated methods in CP2K. It is para...

  7. 4th International Conference on Computational Collective Intel- ligence Technologies and Applications (ICCCI 2012)

    CERN Document Server

    Trawiński, Bogdan; Katarzyniak, Radosław; Jo, Geun-Sik; Advanced Methods for Computational Collective Intelligence

    2013-01-01

    The book consists of 35 extended chapters which have been selected and invited from the submissions to the 4th International Conference on Computational Collective Intelligence Technologies and Applications (ICCCI 2012) held on November 28-30, 2012 in Ho Chi Minh City, Vietnam. The book is organized into six parts, which are semantic web and ontologies, social networks and e-learning, agent and multiagent systems, data mining methods and applications, soft computing, and optimization and control, respectively. All chapters in the book discuss theoretical and practical issues connected with computational collective intelligence and related technologies. The editors hope that the book can be useful for graduate and Ph.D. students in Computer Science, in particular participants in courses on Soft Computing, Multiagent Systems, and Data Mining. This book can be also useful for researchers working on the concept of computational collective intelligence in artificial populations. It is the hope of the editors that ...

  8. FAIL-SAFE: Fault Aware IntelLigent Software for Exascale

    Science.gov (United States)

    2016-06-13

    and that these programs can continue to correct solutions. To broaden the impact of this research, we also needed to be able to ameliorate errors...designing an interface between the application and an introspection framework for resilience ( IFR ) based on the inference engine SHINE; (4) using...the ROSE compiler to translate annotations into reasoning rules for the IFR ; and (5) designing a Knowledge/Experience Database, which will store

  9. YALIN ALTI SİGMA PROJELERİ İÇİN KRİTİK BAŞARI FAKTÖRLERİ (SUCCESS FACTORS FOR LEAN SIX SIGMA PROJECTS

    Directory of Open Access Journals (Sweden)

    Ali Rıza FİRUZAN

    2012-10-01

    Full Text Available Nowadays many companies focus on various kinds of quality improvement techniques to carry the service quality beyond costumer expectations. The selected quality technique should be appropriate to the company's culture and should be sufficient for carry out targeted improvement; this will enhance the company’s superiority in market place.For this purpose, Lean Six Sigma methods are one of the important methods being used today as an intensive use of statistical tools and techniques. Lean Six Sigma methods can be implemented in almost all sectors and successful gains can be obtained. Lean Six Sigma has wide range application in the world. Most applications are successful, while some of them are failed. In this study, reasons for unsuccessful Lean Six Sigma projects are examined. The way to convert unsuccessful project into successful project are suggested. Some solutions are carried out for this purpose.

  10. A Facile Strategy to Enhance the Dielectric and Mechanical Properties of MWCNTs/PVDF Composites with the Aid of MMA-co-GMA Copolymer

    Science.gov (United States)

    Song, Shixin; Xia, Shan; Jiang, Shangkun; Lv, Xue; Sun, Shulin; Li, Quanming

    2018-01-01

    A facile strategy is adopted to prepare carboxylic functionalized multiwalled carbon nanotube (c-MWCNT) modified high dielectric constant (high-k) poly(vinylidene fluoride) (PVDF) composites with the aid of methyl methacrylate-co-glycidyl methacrylate copolymer (MG). The MG is miscible with PVDF and the epoxy groups of the copolymer can react with the carboxylic groups of c-MWCNT, which induce the uniform dispersion of c-MWCNT and a form insulator layer on the surface of c-MWCNT. The c-MWCNTs/MG/PVDF composites with 8 vol % c-MWCNT present excellent dielectric properties with high dielectric constant (~448) and low dielectric loss (~2.36) at the frequency of 1 KHz, the dielectric loss is much lower than the c-MWCNT/PVDF composites without MG. The obvious improvement in dielectric properties ascribes to the existence of MG, which impede the direct contact of c-MWCNTs and PVDF and avoid the formation of conductive network. Therefore, we propose a practical and simple strategy for preparing composites with excellent dielectric properties, which are promising for applications in electronics devices. PMID:29495491

  11. Effects of He{sup +} ion implantation on surface properties of UV-cured Bis-GMA/TEGDMA bio-compatible resins

    Energy Technology Data Exchange (ETDEWEB)

    Fuentes, G.G., E-mail: gfuentes@ain.e [Center of Advanced Surface Engineering, AIN, Cordovilla-Pamplona, E-31191 (Spain); Esparza, J.; Rodriguez, R.J. [Center of Advanced Surface Engineering, AIN, Cordovilla-Pamplona, E-31191 (Spain); Manso-Silvan, M. [Departamento de Fisica Aplicada, Universidad Autonoma de Madrid, Cantoblanco, E-28049 (Spain); Palomares, J. [Instituto de Ciencia de Materiales de Madrid, ICMM-CSIC, Cantoblanco, E-28049 (Spain); Juhasz, J.; Best, S. [Cambridge Centre for Medical Materials, Department of Materials Science and Metallurgy, University of Cambridge, Pembroke Str, Cambridge CB2 3QZ (United Kingdom); Mattilla, R.; Vallittu, P. [Institute of Dentistry, Turku Clinical Biomaterials Centre, Itaeinen Pitkaekatu 4, B FI-20520, Turku (Finland); Achanta, S. [Falex Tribology Wingepark 23 B, 3110 Rotselaar (Belgium); Giazzon, M.; Weder, G. [Centre Suisse d' Electronique et de Microtechnique, CSEM, Jaquet-Drot 1, CH-2002 Neuchatel (Switzerland); Donati, I. [Department of Life Sciences, University of Trieste, Via Licio Giorgieri 1, I 34127 Trieste (Italy)

    2011-01-15

    This work reports on the surface characterisation of 2,2-bis[4-(2-hydroxy-3-methacryloxyl-oxypropoxy)phenyl]propane/triethylene glycol dimethacrylate bio-compatible resins after high energy He{sup +} ion implantation treatments. The samples have been characterised by diffuse reflectance FT-IR, X-ray photo-electron spectroscopy, ultramicro-hardness and nano-scratch wear tests. In addition, osteblast cell assays MG-63 have been used to test the bio-compatibility of the resin surfaces after the ion implantation treatments. It has been observed that the maximum surface hardening of the resin surfaces is achieved at He-ion implantation energies of around 50 keV and fluences of 1 x 10{sup 16} cm{sup -2}. At 50 keV of He-ion bombardment, the wear rate of the resin surface decreases by a factor 2 with respect to the pristine resin. Finally, in vitro tests indicate that the He-ion implantation does not affect to the cell-proliferation behaviour of the UV-cured resins. The enhancement of the surface mechanical properties of these materials can have beneficial consequences, for instance in preventing wear and surface fatigue of bone-fixation prostheses, whose surfaces are continuously held to sliding and shearing contacts of sub-millimetre scale lengths.

  12. High currents, low voltages. Low-cost, high efficiency power supply meets the requirements of Intel Mobile Voltage Positioning; Von dicken Stroemen und kleinen Spannungen. Preiswerte Stromversorgung mit hohem Wirkungsgrad erfuellt die Anforderungen des Intel Mobile Voltage Positioning

    Energy Technology Data Exchange (ETDEWEB)

    Chen, V.W.; Guan, P.; Chen, D. [Linear Technology, CA (United States)

    2001-12-27

    The increasing demands on notebook computers have clock rates and currents and reduced voltages as CPUs are produced in increasingly smaller structural sizes. This makes high demands on power supply. [German] Die steigende Nachfrage nach Rechenleistung in Notebook-Computern hat zu einem betraechtlichen Anstieg der Taktfrequenzen und der Stromaufnahme der CPUs gefuehrt. Gleichzeitig sind die Versorgungsspannungen erheblich gesunken, da die CPUs in Prozessen mit immer kleineren Strukturgroessen hergestellt werden. Als die CPU-Taktfrequenzen 1 GHz ueberstiegen, hat die Stromaufnahme der CPU erstmals 20 A ueberschritten, und die minimale Versorgungsspannung ist auf unter 1 V gefallen. Dies stellt gewaltige Anforderungen an die Stromversorgungen. (orig.)

  13. List-mode PET image reconstruction for motion correction using the Intel XEON PHI co-processor

    Science.gov (United States)

    Ryder, W. J.; Angelis, G. I.; Bashar, R.; Gillam, J. E.; Fulton, R.; Meikle, S.

    2014-03-01

    List-mode image reconstruction with motion correction is computationally expensive, as it requires projection of hundreds of millions of rays through a 3D array. To decrease reconstruction time it is possible to use symmetric multiprocessing computers or graphics processing units. The former can have high financial costs, while the latter can require refactoring of algorithms. The Xeon Phi is a new co-processor card with a Many Integrated Core architecture that can run 4 multiple-instruction, multiple data threads per core with each thread having a 512-bit single instruction, multiple data vector register. Thus, it is possible to run in the region of 220 threads simultaneously. The aim of this study was to investigate whether the Xeon Phi co-processor card is a viable alternative to an x86 Linux server for accelerating List-mode PET image reconstruction for motion correction. An existing list-mode image reconstruction algorithm with motion correction was ported to run on the Xeon Phi coprocessor with the multi-threading implemented using pthreads. There were no differences between images reconstructed using the Phi co-processor card and images reconstructed using the same algorithm run on a Linux server. However, it was found that the reconstruction runtimes were 3 times greater for the Phi than the server. A new version of the image reconstruction algorithm was developed in C++ using OpenMP for mutli-threading and the Phi runtimes decreased to 1.67 times that of the host Linux server. Data transfer from the host to co-processor card was found to be a rate-limiting step; this needs to be carefully considered in order to maximize runtime speeds. When considering the purchase price of a Linux workstation with Xeon Phi co-processor card and top of the range Linux server, the former is a cost-effective computation resource for list-mode image reconstruction. A multi-Phi workstation could be a viable alternative to cluster computers at a lower cost for medical imaging applications.

  14. Code modernization strategies to 3-D Stencil-based applications on Intel Xeon Phi: KNC and KNL

    OpenAIRE

    Cebrián, Juan M.; Cecilia, José M.; Hernández, Mario; García, José M.

    2017-01-01

    Partial Differential Equations (PDEs) are widely used to simulate many scenarios in science and engineering, usually solved through iterative techniques (e.g., Jacobi, Gauss–Seidel). These methods produce an approximate solution to the problem based on Stencil patterns of computation. The complexity, granularity and dimensionality of the problem require of substantial computational resources that are not affordable by regular CPU-based architectures. Emerging massively data-parallel archit...

  15. UAVs: Holy Grail for Intel, Panacea for RSTA, or Much Ado about Nothing? UAVs for the Operational Commander

    National Research Council Canada - National Science Library

    Fox, Roy

    1998-01-01

    ..., operational, and tactical objectives. UAVs have supported military operations including the Vietnam War, the 1983 Israeli War, the Gulf War and most recently the United Nations Peace Keeping Operation in Bosnia, to name a few. Although U.S...

  16. Performance and scalability of finite-difference and finite-element wave-propagation modeling on Intel's Xeon Phi

    NARCIS (Netherlands)

    Zhebel, E.; Minisini, S.; Kononov, A.; Mulder, W.A.

    2013-01-01

    With the rapid developments in parallel compute architectures, algorithms for seismic modeling and imaging need to be reconsidered in terms of parallelization. The aim of this paper is to compare scalability of seismic modeling algorithms: finite differences, continuous mass-lumped finite elements

  17. AstroPhi: программный комплекс для моделирования динамики астрофизических объектов на гибридных суперЭВМ, оснащенных ускорителями Intel Xeon Phi

    OpenAIRE

    Куликов, И. М.; Черных, И. Г.; Глинский, Б. М.; Kulikov, I. M.; Chernykh, I. G.; Glinsky, B. M.

    2013-01-01

    В статье представлен новый сверхмасштабируемый программный комплекс AstroPhi для моделирования динамики астрофизических объектов на гибридных суперЭВМ, оснащенных ускорителями Intel Xeon Phi. Численный метод решения газодинамических уравнений основан на специально адаптированной для реализации на множестве ускорителей комбинации метода крупных частиц и метода Годунова. Для решения уравнения Пуассона используется быстрое преобразование Фурье. Программная реализация была отдельно протести...

  18. Graphene macro-assembly-fullerene composite for electrical energy storage

    Science.gov (United States)

    Campbell, Patrick G.; Baumann, Theodore F.; Biener, Juergen; Merrill, Matthew; Montalvo, Elizabeth; Worsley, Marcus A.; Biener, Monika M.; Hernandez, Maira Raquel Ceron

    2018-01-16

    Disclosed here is a method for producing a graphene macro-assembly (GMA)-fullerene composite, comprising providing a GMA comprising a three-dimensional network of graphene sheets crosslinked by covalent carbon bonds, and incorporating at least 20 wt. % of at least one fullerene compound into the GMA based on the initial weight of the GMA to obtain a GMA-fullerene composite. Also described are a GMA-fullerene composite produced, an electrode comprising the GMA-fullerene composite, and a supercapacitor comprising the electrode and optionally an organic or ionic liquid electrolyte in contact with the electrode.

  19. Study of lamellar structure and crystallization behavior of poly(butylene terephthalate (PBT) in PBT/ABS and PBT/ABS/MMA-GMA blends using DSC, SAXS and DMTA

    International Nuclear Information System (INIS)

    Mantovani, Gerson L.; Pessan, Luiz A.; Hage, Elias; Torriani, Iris L.

    2001-01-01

    The effects of processing conditions and blend composition in the crystallization behaviour and lamellar structure of poly(butylene terephthalate) (PBT) in blends with acrylonitrile-butadiene-styrene copolymer (ABS) were studied. Differential scanning calorimetry (DSC), small-angle X-ray scattering (SAXS) and dynamic mechanical thermal analysis (DMTA) were used to observe those effects. Addition of reactive acrylic compatibilizer to the PBT/ABS blends has promoted an increase in the heat of crystallization of the related blends. The Long Period (L), obtained from the peak in the Lorentz-corrected SAXS pattern, was used to observe the effect in the lamellar structure of PBT phase in the blends. The results were in good agreement with the calculated values from de correlation function and the values of L do not show a significant dependence with the PBT mass fraction, either in the binary blends (PBT/ABS) or in the compatibilized blends. A slight but clear increase of the long period (from 3 to 5 angstrom) is noted for the systems injection molded at 240 deg C when compared to the ones molded at 260 deg C, although PBT crystallinity in the blends does not change significantly with blend composition or processing conditions. DMTA curves show a slight shift in the temperature of the tan δ main peaks for both PBT and ABS phases in the compatibilized blends, thereby indicating changes in the degree of miscibility or interaction between phases of those blends. Changes in the compatibilized blends miscibility may be responsible by the effects in the crystallization behaviour and lamellar structure of the PBT/ABS blends. (author)

  20. Study of lamellar structure and crystallization behavior of poly(butylene terephthalate (PBT) in PBT/ABS and PBT/ABS/MMA-GMA blends using DSC, SAXS and DMTA

    Energy Technology Data Exchange (ETDEWEB)

    Mantovani, Gerson L.; Pessan, Luiz A.; Hage, Elias [Sao Carlos Univ., SP (Brazil). Dept. de Engenharia de Materiais]. E-mail: elias@power.ufscar.br; Plivelic, Tomas S. [Laboratorio Nacional de Luz Sincrotron (LNLS), Campinas, SP (Brazil); Torriani, Iris L. [Universidade Estadual de Campinas, SP (Brazil). Inst. de Fisica Gleb Wataghin

    2001-07-01

    The effects of processing conditions and blend composition in the crystallization behaviour and lamellar structure of poly(butylene terephthalate) (PBT) in blends with acrylonitrile-butadiene-styrene copolymer (ABS) were studied. Differential scanning calorimetry (DSC), small-angle X-ray scattering (SAXS) and dynamic mechanical thermal analysis (DMTA) were used to observe those effects. Addition of reactive acrylic compatibilizer to the PBT/ABS blends has promoted an increase in the heat of crystallization of the related blends. The Long Period (L), obtained from the peak in the Lorentz-corrected SAXS pattern, was used to observe the effect in the lamellar structure of PBT phase in the blends. The results were in good agreement with the calculated values from de correlation function and the values of L do not show a significant dependence with the PBT mass fraction, either in the binary blends (PBT/ABS) or in the compatibilized blends. A slight but clear increase of the long period (from 3 to 5 angstrom) is noted for the systems injection molded at 240 deg C when compared to the ones molded at 260 deg C, although PBT crystallinity in the blends does not change significantly with blend composition or processing conditions. DMTA curves show a slight shift in the temperature of the tan {delta} main peaks for both PBT and ABS phases in the compatibilized blends, thereby indicating changes in the degree of miscibility or interaction between phases of those blends. Changes in the compatibilized blends miscibility may be responsible by the effects in the crystallization behaviour and lamellar structure of the PBT/ABS blends. (author)

  1. Proposal for the award of blanket contracts for the supply of Intel-based desktop PCs, display monitors and portable PCs

    CERN Document Server

    2000-01-01

    This document concerns the award of blanket contracts for the supply of the three following categories of equipment for the period 2001-2004: a) desktop PCs (complete PC systems but without display monitors), b) display monitors (conventional CRTs or flat screen LCDs) and c) portable PCs (also called notebooks or laptops). Following a market survey carried out among 41 firms in fourteen Member States, an invitation to tender (IT-2692/IT) was sent on 19 May 2000 to 12 firms and three consortia, each consisting of two firms, in five Member States. By the closing date, CERN had received seven tenders, all from the Swiss subsidiaries of the firms and consortia. The Finance Committee is invited to agree to the negotiation of - blanket contracts with VOBIS (CH), ELONEX (CH) and FUJITSU-SIEMENS (CH), the three lowest bidders complying with the specification, for the supply of Desktop PCs; - blanket contracts with VOBIS (CH), SYNOPTIC (CH) and ELONEX (CH), the three lowest bidders offering display monitors manufactur...

  2. Projecte bàsic d'una nau d'emmagatzematge intel·ligent al ZAL Prat de Llobregat

    OpenAIRE

    Moli Barrufet, Gemma; Genius Jimenez, Xavier

    2009-01-01

    El objetivo del presente proyecto es el análisis y estudio de la viabilidad de construcción de un almacén logístico nodal para la distribución de artículos deportivos y de ocio de una empresa de ventas en grandes superficies. Para el desarrollo de la justificación se han elegido dos alternativas de entre todas las posibles: Un almacén convencional de tres cuerpos para mercancías paletizadas en estanterías y un almacén automatizado con dos cuerpos de recepción y expedición más u...

  3. Ironies de l'assaig. Ors, Pla, Fuster: història intel·lectual de l'adhesió incompleta

    Directory of Open Access Journals (Sweden)

    Antoni Martí Monterde

    2014-07-01

    Full Text Available The main goal of this article is to bring up the topic of irony in the essay as a literary genre, based on the considerations made by Eugeni d’Ors, Josep Pla and Joan Fuster. The emergence of the definition of irony as an incomplete adhesion, which refers to Ors although it has lasted especially through Pla, is revised here; the intellectual history of the definition is analyzed in order to consider in which moment Fuster’s essay relates to it and, taking irony as a starting point, it gives a boost to ontemporary Catalan essay.

  4. How Intel Inc. Utilizing its E-mails%英特尔公司怎样利用电子邮件?

    Institute of Scientific and Technical Information of China (English)

    王鹭

    2001-01-01

    @@ 全球最大的电脑芯片生产商英特尔公司平均每天要发出三百万份电子邮件!这么大的数量足以让任何其他小公司的电脑系统窒息瘫痪,甚至效率最高的公司也不能幸免.然而,这个硅谷的巨人究竟如何管理、控制并利用电子邮件这个新式的商业武器,使其发挥出最大的效能昵?

  5. Optimizing Excited-State Electronic-Structure Codes for Intel Knights Landing: A Case Study on the BerkeleyGW Software

    Energy Technology Data Exchange (ETDEWEB)

    Deslippe, Jack; da Jornada, Felipe H.; Vigil-Fowler, Derek; Barnes, Taylor; Wichmann, Nathan; Raman, Karthik; Sasanka, Ruchira; Louie, Steven G.

    2016-10-06

    We profile and optimize calculations performed with the BerkeleyGW code on the Xeon-Phi architecture. BerkeleyGW depends both on hand-tuned critical kernels as well as on BLAS and FFT libraries. We describe the optimization process and performance improvements achieved. We discuss a layered parallelization strategy to take advantage of vector, thread and node-level parallelism. We discuss locality changes (including the consequence of the lack of L3 cache) and effective use of the on-package high-bandwidth memory. We show preliminary results on Knights-Landing including a roofline study of code performance before and after a number of optimizations. We find that the GW method is particularly well-suited for many-core architectures due to the ability to exploit a large amount of parallelism over plane-wave components, band-pairs, and frequencies.

  6. Ada Compiler Validation Summary Report: Certificate Number: 940325S1. 11352 DDC-I DACS Sun SPARC/Solaries to Pentium PM Bare Ada Cross Compiler System, Version 4.6.4 Sun SPARCclassic = Intel Pentium (Operated as Bare Machine) Based in Xpress Desktop (Intel Product Number: XBASE6E4F-B)

    Science.gov (United States)

    1994-03-25

    Best Available Copy REPORT DOCUMENTATION PAGE _V -ONC Uft Xaf. WO -" Am u~~ ns~ 940325SI. 11352 , AVV: 94ddc5OO_3d. Compiler: DACS Sun SPARC/ aonais to...Manual for the Ada Proarammina Language, ANSI/MIL-STD-1815A, February 1983 and ISO 8652-1987. [Pro92] Ada Coupiler Validation Procedures, Version 3.1...objectives found to be irrelevant for the given Ada implementation. ISO International Organization for Standardization. LRM The Ada standard, or

  7. What's New in Computers

    Indian Academy of Sciences (India)

    In late 1996 Intel announced an enhancement of the Pentium. Processor architecture and christened it MMX technology or multimedia extensions. The Intel MMX technology is purportedly the most significant enhancement to the Intel architecture since the extension of the x86 architecture to 32 bits in 1985 when Intel first ...

  8. Improvement of cytocompatibility of polylactide by filling with marine algae powder

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Tung-Yi [Department of Materials Science and Engineering, National Taiwan University of Science and Technology, Taipei 10607, Taiwan (China); Yang, Ming-Chien, E-mail: myang@mail.ntust.edu.tw [Department of Materials Science and Engineering, National Taiwan University of Science and Technology, Taipei 10607, Taiwan (China); Hsu, Yi-Chiang [Graduate Institute of Medical Science, College of Health Sciences, Chang Jung Christian University, Tainan 71101, Taiwan (China); Innovative Research Center of Medicine, College of Health Sciences, Chang Jung Christian University, Tainan 71101, Taiwan (China)

    2015-05-01

    This work evaluated the cytocompatibility, thermal and mechanical properties of composites of polylactide (PLA) and marine algae powder (MAP). To improve the thermal and mechanical properties of PLA–MAP composites, glycidyl methacrylate (GMA) was used as the compatibilizer for the blending of PLA and MAP. The PLA-g-GMA/MAP composites exhibited superior mechanical properties, attributing to higher compatibility between the polymer and MAP, comparing to PLA/MAP composites. The dispersion of MAP in the PLA-g-GMA matrix was highly homogeneous as a result of etherification. The lower melt torque of the PLA-g-GMA/MAP composites also made them more processable than PLA/MAP. To assess the cytocompatibility, normal human foreskin fibroblasts (FBs) were seeded onto each type of the composites. Results of FB proliferation, collagen production, and cytotoxicity assays indicated greater cytocompatibility for the PLA/MAP composites than for the PLA-g-GMA/MAP composites. Furthermore, both PLA/MAP and PLA-g-GMA/MAP composites were more cytocompatible than pure PLA. - Highlights: • PLA was grafted with GMA to form ether bond with marine algae powder (MAP). • Composites of PLA-g-GMA and MAP exhibited cytocompatibility with fibroblasts. • PLA-g-GMA/MAP composites exhibited mechanical properties superior to PLA/MAP. • PLA-g-GMA/MAP composites were more processable than PLA/MAP.

  9. Production of sorption-active polypropylene fibers by radiation-induce grafting of glycidyl methacrylate as a precursor monomer

    International Nuclear Information System (INIS)

    Bondar, Yu.V.; Kim, H.J.; Lim, Y.J.; Kravets, L.I.

    2004-01-01

    Full text: Two types of sorption-active polypropylene fiber carrying strong-acid sulfonate groups and amino groups have been synthesized by radiation-induced graft polymerization of glycidyl methacrylate (GMA) with subsequent chemical modification of the epoxy groups of poly-GMA graft chains. The effect of various polymerization parameters on the GMA grafting degree was investigated in detail. The epoxy ring-opening of poly-GMA graft chains with introduction of strong-acid sulfonate groups was carried out with sodium hydrogen sulfite in water-dimethylformamide solution at 70 o C. The main peculiarities of the sulfonation reaction in depending on the reaction time and GMA grafting degree have been investigated. It was shown that for the samples with GMA grafting degree more than 50% two simultaneous processes take place during the sulfonation reaction, namely the incorporation of the sulfonate groups via opening of the GMA epoxy-rings as well as hydrolysis of the GMA epoxy-rings with the formation of α-glycol groups. Amine groups were incorporated by treatment of GMA-grafted polypropylene fibers with excess of diethylene triamine reagent. The conversion of the epoxy groups into the functional groups was investigated as a function of the degree of GMA grafting and reaction time. The ion-exchange characteristics of obtained sorption-active polypropylene fibers were determined

  10. Production of sorption-active polypropylene fiber by radiation-induce grafting of glycidyl methacrylate as a precursor monomer

    International Nuclear Information System (INIS)

    Bondar, Yu.V.; Kim, H.J.; Lim, Y.J.; Kravets, L.I.

    2004-01-01

    Two types of sorption-active polypropylene fiber carrying strong-acid sulfonate groups and amino groups have been synthesized by radiation-induced graft polymerization of glycidyl methacrylate (GMA) with subsequent chemical modification of the epoxy groups of poly-GMA graft chains. The effect of various polymerization parameters on the GMA grafting degree was investigated in detail. The epoxy ring-opening of poly-GMA graft chains with introduction of strong-acid sulfonate groups was carried out with sodium hydrogen sulfite in water-dimethylformamide solution at 70 o C. The main peculiarities of the sulfonation reaction in depending on the reaction time and GMA grafting degree have been investigated. It was shown that for the samples with GMA grafting degree more than 50% two simultaneous processes take place during the sulfonation reaction, namely the incorporation of the sulfonate groups via opening of the GMA epoxy-rings as well as hydrolysis of the GMA epoxy-rings with the formation of α-glycol groups. Amine groups were incorporated by treatment of GMA-grafted polypropylene fibers with excess of diethylene triamine reagent. The conversion of the epoxy groups into the functional groups was investigated as a function of the degree of GMA grafting and reaction time. The ion-exchange characteristics of obtained sorption-active polypropylene fibers were determined. (author)

  11. Improvement of cytocompatibility of polylactide by filling with marine algae powder

    International Nuclear Information System (INIS)

    Wu, Tung-Yi; Yang, Ming-Chien; Hsu, Yi-Chiang

    2015-01-01

    This work evaluated the cytocompatibility, thermal and mechanical properties of composites of polylactide (PLA) and marine algae powder (MAP). To improve the thermal and mechanical properties of PLA–MAP composites, glycidyl methacrylate (GMA) was used as the compatibilizer for the blending of PLA and MAP. The PLA-g-GMA/MAP composites exhibited superior mechanical properties, attributing to higher compatibility between the polymer and MAP, comparing to PLA/MAP composites. The dispersion of MAP in the PLA-g-GMA matrix was highly homogeneous as a result of etherification. The lower melt torque of the PLA-g-GMA/MAP composites also made them more processable than PLA/MAP. To assess the cytocompatibility, normal human foreskin fibroblasts (FBs) were seeded onto each type of the composites. Results of FB proliferation, collagen production, and cytotoxicity assays indicated greater cytocompatibility for the PLA/MAP composites than for the PLA-g-GMA/MAP composites. Furthermore, both PLA/MAP and PLA-g-GMA/MAP composites were more cytocompatible than pure PLA. - Highlights: • PLA was grafted with GMA to form ether bond with marine algae powder (MAP). • Composites of PLA-g-GMA and MAP exhibited cytocompatibility with fibroblasts. • PLA-g-GMA/MAP composites exhibited mechanical properties superior to PLA/MAP. • PLA-g-GMA/MAP composites were more processable than PLA/MAP

  12. Problem Solvıng In Enterprıses, the Importance of Emotıonal Intellıgence and Applıcatıon Process

    OpenAIRE

    Kayaoz, Veysel

    2015-01-01

    Gender has no significance in terms of personality of the personnel, and also combative personality traits of the personnel in terms of workingduration variant within enterprise, social personality traits of the personnel in terms of the department variant within the personnel work,dreamy personality traits of the personnel in terms of the position variant within the enterprise, combative social, dreamy and enterprisingpersonality traits of the personnel in terms of the position variant withi...

  13. Estudi dels processos emocionals en nens i nenes amb dificultats d'aprenentatge i la seva relació amb els processos cognitius basats en la Teoria PASS de la Intel·ligència

    OpenAIRE

    Alabau i Bofill, Judith

    2003-01-01

    A lo largo de estos años de existencia del grupo de investigación se han ido desarrollando un volumen de casos donde se comenzó a evidenciar un hecho: niños y adolescentes llegaban derivados a la consulta por problemas de aprendizaje, pero éstos no siempre respondían a que tuvieran unos procesos cognitivos por debajo de la media. Por tanto, no se explicaba su bajo rendimiento escolar. Ante estos casos nos planteamos como intervenir en esta realidad educativa. Indagando descubrimos que la mayo...

  14. Effects of molecular structure of the resins on the volumetric shrinkage and the mechanical strength of dental restorative composites.

    Science.gov (United States)

    Kim, L U; Kim, J W; Kim, C K

    2006-09-01

    To prepare a dental composite that has a low amount of curing shrinkage and excellent mechanical strength, various 2,2-bis[4-(2-hydroxy-3-methacryloyloxy propoxy) phenyl] propane (Bis-GMA) derivatives were synthesized via molecular structure design, and afterward, properties of their mixtures were explored. Bis-GMA derivatives, which were obtained by substituting methyl groups for hydrogen on the phenyl ring in the Bis-GMA, exhibited lower curing shrinkage than Bis-GMA, whereas their viscosities were higher than that of Bis-GMA. Other Bis-GMA derivatives, which contained a glycidyl methacrylate as a molecular end group exhibited reduced curing shrinkage and viscosity. Methoxy substitution for hydroxyl groups on the Bis-GMA derivatives was performed for the further reduction of the viscosity and curing shrinkage. Various resin mixtures, which had the same viscosity as the commercial one, were prepared, and their curing shrinkage was examined. A resin mixture containing 2,2-bis[3,5-dimethyl, 4-(2-methoxy-3-methacryloyloxy propoxy) phenyl] propane] (TMBis-M-GMA) as a base resin and 4-tert-butylphenoxy-2-methyoxypropyl methacrylate (t-BP-M-GMA) as a diluent exhibited the lowest curing shrinkage among them. The composite prepared from this resin mixture also exhibited the lowest curing shrinkage along with enhanced mechanical properties.

  15. Synthesis and characterization of monosize magnetic poly(glycidyl methacrylate) beads

    Institute of Scientific and Technical Information of China (English)

    Evrim Banu Alt1nta(s); Lokman Uzun; Adil Denizli

    2007-01-01

    Monosize, 1.6 μm, magnetic beads of poly(glycidyl methacrylate) [M-poly(GMA)], were prepared by dispersion polymerization in the presence of Fe3O4 nano-powder. Monosize M-poly(GMA) beads were characterized by swelling tests, density measurements, electron spin resonance (ESR), vibrating sample magnetometer (VSM) and scanning electron microscopy (SEM). The characteristic functional groups of M-poly(GMA)beads were analyzed by Fourier transform infrared spectrometer (FTIR). The M-poly(GMA) beads are highly uniform in size and have a spherical shape and non-porous structure. Polydispersity index (PDI) of M-poly(GMA) beads was calculated to be around 1.008. The hydrated density of the M-poly(GMA) beads measured at 25 ℃ was 1.14 g/cm3. The content of oxirane groups on the surface of the M-poly(GMA) sample was found to be 3.46 mmol/g by using perchloric acid titration. The specific surface area of the M-poly(GMA) beads was determined to be 3.2 m2/g.The equilibrium swelling ratio was 52%. The volume fraction of magnetite nanopowder in the M-poly(GMA) beads was found to be 4.5%. The g factor, that can be considered as a quantity characteristic of the molecules in which the unpaired electrons are located, was found to be 2.28for M-poly(GMA). The external magnetic field at resonance was calculated to be 2055 Gs which was found sufficient to excite all of the dipole moments present in 1.0 g of M-poly(GMA) sample.

  16. 76 FR 32372 - Notice of Receipt of Complaint; Solicitation of Comments Relating to the Public Interest

    Science.gov (United States)

    2011-06-06

    ... Rica S.A. of Costa Rica, Intel Malaysia Sdn. Bhd of Malaysia, Intel (Philippines) of the Philippines... any public health, safety, or welfare concerns in the United States relating to the potential orders...

  17. Software Aspects of IEEE Floating-Point Computations for Numerical Applications in High Energy Physics

    CERN Multimedia

    CERN. Geneva

    2010-01-01

    hazards to be avoided About the speaker Jeffrey M Arnold is a Senior Software Engineer in the Intel Compiler and Languages group at Intel Corporation. He has been part of the Digital->Compaq->Intel compiler organization for nearly 20 years; part of that time, he worked on both lo...

  18. Scalable Architectures : The Future is Multicore

    NARCIS (Netherlands)

    Juurlink, B.; Meenderinck, C.

    2008-01-01

    “The future is multicore”, it sounds like a slogan from an Intel commercial. Indeed, a few years ago Intel introduced the Core Duo microprocessor and, more recently, quad-core technology. But, is it all pure marketing? Was Intel tired of advertising with clock frequencies? Did they need another buzz

  19. Cognitive Medical Wireless Testbed System (COMWITS)

    Science.gov (United States)

    2016-11-01

    Number: ...... ...... Sub Contractors (DD882) Names of other research staff Inventions (DD882) Scientific Progress This testbed merges two ARO grants...bit 64 bit CPU Intel Xeon Processor E5-1650v3 (6C, 3.5 GHz, Turbo, HT , 15M, 140W) Intel Core i7-3770 (3.4 GHz Quad Core, 77W) Dual Intel Xeon

  20. Grapho-Morphological Awareness in Spanish L2 Reading: How Do Learners Use This Metalinguistic Skill?

    Science.gov (United States)

    Miguel, Nausica Marcos

    2012-01-01

    This paper contributes to the literature on the transferability of grapho-morphological awareness (GMA) for second language (L2) learners by analysing L2 learners' knowledge of morphology in reading. GMA helps readers to identify grammatical categories, infer meanings of unfamiliar words, and access stored lexical information. Previous research…

  1. Quantitative aspects of enzyme histochemistry on sections of freeze-substituted glycol methacrylate-embedded rat liver

    NARCIS (Netherlands)

    Frederiks, W. M.; Bosch, K. S.

    1993-01-01

    Freeze-substituted rat liver embedded in glycol methacrylate (GMA) has been used to demonstrate the activities of several enzymes. The following enzymes could be detected in GMA-sections by the indicated histochemical procedure(s): 5'-nucleotidase (lead salt, cerium-diaminobenzidine), alkaline

  2. Modification of macroporous membranes by graft co-polymerization induced by pre-irradiation with an electron accelerator; Modificacion de membranas macroporosas para la recuperacion de protemas por intercambio ionico

    Energy Technology Data Exchange (ETDEWEB)

    Grasselli, M [Buenos Aires Univ. (Argentina). Facultad de Farmacia y Bioquimica; Yoshii, Fumio [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment

    1999-07-01

    Glycidyl methacrylate (GMA) and N,N-dimethylacrylamide (DMAA) have been co-grafted on hollow fiber membranes of macroporous polyethylene. Grafted copolymers have been obtained with different ratios of the monomers (molar ratio between 0 and 2 DMAA/GMA). The properties of the modified membranes are studied.

  3. Modification of macroporous membranes by graft co-polymerization induced by pre-irradiation with an electron accelerator

    International Nuclear Information System (INIS)

    Grasselli, M.; Yoshii, Fumio

    1999-01-01

    Glycidyl methacrylate (GMA) and N,N-dimethylacrylamide (DMAA) have been co-grafted on hollow fiber membranes of macroporous polyethylene. Grafted copolymers have been obtained with different ratios of the monomers (molar ratio between 0 and 2 DMAA/GMA). The properties of the modified membranes are studied

  4. Preparation of epoxy-functionalized methyl methacrylate-butadiene-styrene core-shell particles and investigation of their dispersion in polyamide-6

    NARCIS (Netherlands)

    Aerdts, A.M.; Groeninckx, G.; Zirkzee, H.F.; Aert, van H.A.M.; Geurts, J.M.

    1997-01-01

    Functional core—shell impact modifiers of glycidyl methacrylate (GMA) functionalized methyl methacrylate—butadiene—styrene (MBS) have been prepared via a seeded semi-continuous emulsion polymerization. These functional MBS—GMA particles were blended with polyamide-6. Investigations by transmission

  5. THE EFFECTS OF GLYCOL METHACRYLATE AS A DEHYDRATING AGENT ON THE DIMENSIONAL CHANGES OF LIVER-TISSUE

    NARCIS (Netherlands)

    GERRITS, PO; HOROBIN, RW; STOKROOS, [No Value

    The dimensional changes of liver sections during the course of processing with glycol methacrylate (GMA) or with ethanol are described. Tissue processing with ethanol served as a control. During prolonged processing steps (24 h each), linear shrinkage of tissue specimens dehydrated with GMA at room

  6. The Sensitive, Imaginative, Articulate Art Student and Conservative, Cool, Numerate Science Student: Individual Differences in Art and Science Students

    Science.gov (United States)

    Furnham, Adrian; Crump, John

    2013-01-01

    In all 794 young people aged around 30 yrs completed three intelligence (Raven's Progressive matrices: GMA Numerical and GMA Verbal) and one personality inventory (16PF). They were all graduates and 173 were identified clearly as Arts graduates and 518 as Science students. There were various sex differences on all measures. All seven hypotheses…

  7. An association between geomagnetic activity and dream bizarreness.

    Science.gov (United States)

    Lipnicki, Darren M

    2009-07-01

    Daily disturbances of the earth's magnetic field produce variations in geomagnetic activity (GMA) that are reportedly associated with widespread effects on human health and behaviour. Some of these effects could be mediated by an established influence of GMA on the secretion of melatonin. There is evidence from unrelated research that melatonin influences dream bizarreness, and it is hypothesised here that there is an association between GMA and dream bizarreness. Also reported is a preliminary test of this hypothesis, a case study in which the dreams recorded over 6.5 years by a young adult male were analysed. Reports of dreams from the second of two consecutive days of either low or high GMA (K index sum or = 28) were self-rated for bizarreness on a 1-5 scale. Dreams from low GMA periods (n=69, median bizarreness=4) were found to be significantly more bizarre than dreams from high GMA periods (n=85, median bizarreness=3; p=0.006), supporting the hypothesised association between GMA and dream bizarreness. Studies with larger samples are needed to verify this association, and to determine the extent to which melatonin may be involved. Establishing that there is an association between GMA and dream bizarreness would have relevance for neurophysiological theories of dreaming, and for models of psychotic symptoms resembling bizarre dream events.

  8. Osteointegration of a bisphenol-a-glycidyl-dimethacrylate composite and its use in anterior skull base defects: an experimental study in an experimental design model of cerebrospinal fluid leak.

    Science.gov (United States)

    Sanus, Galip Zihni; Kucukyuruk, Baris; Biceroglu, Huseyin; Isler, Cihan; Tanriverdi, Taner; Bas, Ahmet; Albayram, Sait; Kurkcu, Mehmet; Oz, Buge

    2014-07-01

    Promising clinical results were reported in watertight closure of anterior skull base defects (ASBDs) with bisphenol-a-glycidyl-dimethacrylate (bis-GMA)-based materials to prevent the cerebrospinal fluid leaks. However, interrelation of these materials with surrounding bones in histologic level, referred to as the osteointegration, has not been reported in the anterior skull base. In addition, an illustrative case with an ASBD that was repaired using a bis-GMA composite has been presented. Twenty New Zealand rabbits were divided into 4 groups: control and sham groups consisted of 2 and 6 rabbits, respectively. The "skull base defect" group (n = 6) underwent a unifrontal craniectomy and an iatrogenic ASBD followed by creating a dural defect to obtain a cerebrospinal fluid leak. Similar bony and dural defects were acquired in the "repair with bis-GMA based allograft" group (n = 6), but the bony defect was closed with bis-GMA-based allograft. All animals in the "skull base defect" group died in 3 weeks after surgery. There were no animal losses in the "repair with bis-GMA based allograft" group at the sixth month. Histologic evaluation revealed complete osteointegration of bis-GMA composite with surrounding bones. bis-GMA based allograft achieved a watertight repair of the ASBD. Histologic findings of this study showed that bis-GMA composite is a reliable material to be used in the closure of anterior skull base bony defects.

  9. Synthesis and Properties of Reactive Interfacial Agents for Polycaprolactone-Starch Blends

    NARCIS (Netherlands)

    Sugih, Asaf K.; Drijfhout, Jan. P.; Picchioni, Francesco; Janssen, Leon P. B. M.; Heeres, Hero J.

    2009-01-01

    The synthesis of two reactive interfacial agents for starch-polycaprolactone (PCL) blends, PCL-g-glycidyl methacrylate (PCL-g-GMA) and PCL-g-diethyl maleate (PCL-g-DEM) is described. The compounds were prepared by reacting a low molecular weight PCL. (M(w) 3000) with GMA or DEM in the presence of

  10. Formal training in general movement assessment is required to effectively evaluate infants with perinatal asphyxia in outpatient settings

    DEFF Research Database (Denmark)

    Brown, Annemette K; Greisen, Gorm; Haugsted, Ulla

    2016-01-01

    recordings to assess GMA, in a busy Danish outpatient clinic. METHODS: The study comprised 30-term infants born with perinatal asphyxia, who were video recorded at three months. They were assessed by two certified GMA observers and re-assessed two weeks later. Interobserver and intra-observer agreements were...

  11. When intelligence is (dys)functional for achieving sales performance

    NARCIS (Netherlands)

    Verbeke, W.J.; Belschak, F.D.; Bakker, A.B.; Dietz, B.

    2008-01-01

    Using two samples of salespeople, the authors investigate how a combination of general mental ability (GMA) and specific skills and capabilities (social competence and thinking styles) enables salespeople to reach their sales goals. The study finds evidence for an interaction between GMA and social

  12. Optimization of process parameter for graft copolymerization of glycidyl methacrylate onto delignified banana fibers

    International Nuclear Information System (INIS)

    Selambakkannu, S.; Nor Azillah Fatimah Othman; Siti Fatahiyah Mohamad

    2016-01-01

    This paper focused on pre-treated banana fibers as a trunk polymer for optimization of radiation-induced graft copolymerization process parameters. Pre-treated banana fiber was grafted with glycidyl methacrylate (GMA) via electron beam irradiation. Optimization of grafting parameters in term of grafting yield was analyzed at numerous radiation dose, monomer concentration and reaction time. Grafting yield had been calculated gravimetrically against all the process parameters. The grafting yield at 40 kGy had increases from 14 % to 22.5 % at 1 h and 24 h of reaction time respectively. Grafting yield at 1 % of GMA was about 58 % and it increases to 187 % at 3 % GMA. The grafting of GMA onto pre-treated banana fibers confirmed with the characterization using FTIR, SEM and TGA. Grafting of GMA onto pre-treated fibers was successfully carried out and it was confirmed by the results obtained via the characterization. (author)

  13. Toughening modification of poly(butylene terephthalate)/poly(ethylene terephthalate) blends by an epoxy-functionalized elastomer

    Science.gov (United States)

    Zhang, Weizhou; Wang, Kai; Yan, Wei; Guo, Weihong

    2017-10-01

    New toughened poly(butylene terephthalate) (PBT)/poly(ethylene terephthalate) (PET) (40/60 wt%) blends were obtained by melting with Glycidyl methacrylate grafted poly(ethylene octane) copolymer (POE-g-GMA), varying the POE-g-GMA content up to 20 wt%, in a twin-screw extruder, followed by injection molding. The influence of POE-g-GMA on the properties of the PBT/PET blends was investigated by mechanical testing, Fourier transform infrared (FT-IR) analysis, gel fractions analysis, dynamic mechanical analysis (DMA), differential scanning calorimetry (DSC) and scanning electronic microscopy (SEM). The mechanical testing results indicated that the incorporation of POE-g-GMA led to increases in the notched impact strength and decreases in the tensile strength, flexural strength, and flexural modulus. When POE-g-GMA content reached 20 wt%, the notched impact strength (8.0 kJ m-2) was achieved for the PBT/PET/POE-g-GMA blends. FT-IR results proved that some PBT/PET/POE-g-GMA copolymers were produced, which improved the compatibility between POE-g-GMA and the PBT/PET matrix. The extent of crosslinking was observed by gel fraction measurements. DMA results further testified chain-extending and micro-crosslink reactions occurred between POE-g-GMA and PBT/PET blends. In addition, the reactions induced by POE-g-GMA affected the crystallization behavior of PBT/PET blends obviously, as observed from DSC results. By means of SEM observation of the impact fracture surface morphology, and the discussion of the micro-crosslink reaction process between the epoxide-containing elastomers and PBT/PET matrix, the toughening mechanism was proposed to be taken into account the shear yielding of PBT/PET matrix and cavitation of elastomer particles.

  14. Posidonia oceanica as a Renewable Lignocellulosic Biomass for the Synthesis of Cellulose Acetate and Glycidyl Methacrylate Grafted Cellulose

    Directory of Open Access Journals (Sweden)

    Elena Vismara

    2013-05-01

    Full Text Available High-grade cellulose (97% α-cellulose content of 48% crystallinity index was extracted from the renewable marine biomass waste Posidonia oceanica using H2O2 and organic peracids following an environmentally friendly and chlorine-free process. This cellulose appeared as a new high-grade cellulose of waste origin quite similar to the high-grade cellulose extracted from more noble starting materials like wood and cotton linters. The benefits of α-cellulose recovery from P. oceanica were enhanced by its transformation into cellulose acetate CA and cellulose derivative GMA-C. Fully acetylated CA was prepared by conventional acetylation method and easily transformed into a transparent film. GMA-C with a molar substitution (MS of 0.72 was produced by quenching Fenton’s reagent (H2O2/FeSO4 generated cellulose radicals with GMA. GMA grafting endowed high-grade cellulose from Posidonia with adsorption capability. GMA-C removes β-naphthol from water with an efficiency of 47%, as measured by UV-Vis spectroscopy. After hydrolysis of the glycidyl group to glycerol group, the modified GMA-C was able to remove p-nitrophenol from water with an efficiency of 92%, as measured by UV-Vis spectroscopy. α-cellulose and GMA-Cs from Posidonia waste can be considered as new materials of potential industrial and environmental interest.

  15. Surface treatment of poly(ethylene terephthalate) by gamma-ray induced graft copolymerization of methyl acrylate and its toughening effect on poly(ethylene terephthalate)/elastomer blend

    International Nuclear Information System (INIS)

    Ma, Liang; Wang, Mozhen; Ge, Xuewu

    2013-01-01

    To improve the compatibility between ethylene-methyl acrylate-glycidyl methacrylate random terpolymer (E-MA-GMA) elastomer and poly(ethylene terephthalate) (PET), thereby enhance the toughening effect of E-MA-GMA on PET, γ-radiation-induced graft copolymerization technique was used to graft methyl acrylate (MA) monomer onto PET. The produced PET-g-PMA copolymer can be used as a self-compatibilizer in PET/E-MA-GMA blend since the copolymer contains the same segments, respectively, with PET and E-MA-GMA. The impact strength of PET/E-MA-GMA blend increased nearly by 30% in the presence of less than 0.1 wt% PET-g-PMA compared with that of the neat PET/elastomer blend, without loss of the tensile strength of the blends. This work proposed a potential application of radiation-induced grafting copolymerization technique on the in-situ compatibilization of PET/elastomer blends so as to improve the integral mechanical properties of PET based engineering plastic. - Highlights: • PMA was grafted onto PET resins by γ-ray radiation-induced copolymerization. • The obtained PET-g-PMA can improve the compatibility between PET and E-MA-GMA. • A small amount of PET-g-PMA can enhance the impact strength of PET/E-MA-GMA blend

  16. Peripheral Blood CD64 Levels Decrease in Crohn’s Disease following Granulocyte and Monocyte Adsorptive Apheresis

    Directory of Open Access Journals (Sweden)

    Toshimi Chiba

    2011-12-01

    Full Text Available Granulocyte and monocyte adsorptive apheresis (GMA is reportedly useful as induction therapy for Crohn’s disease (CD. However, the effects of GMA on CD64 have not been well characterized. We report here our assessment of CD64 expression on neutrophils before and after treatment with GMA in two patients with CD. The severity of CD was assessed with the CD activity index (CDAI. The duration of each GMA session was 60 min at a flow rate of 30 ml/min as per protocol. CD64 expression on neutrophils was measured by analyzing whole blood with a FACScan flow cytometer. In case 1, CD64 levels after each session of GMA tended to decrease compared to pretreatment levels, whereas in case 2, CD64 levels dropped significantly after treatment. The CDAI decreased after GMA in both cases 1 and 2. A significant correlation was noted between CDAI scores and CD64 levels in both cases. In conclusion, GMA reduced blood CD64 levels, which would be an important factor for the decrease of CDAI scores.

  17. Studies on the effect of compatibilizers on mechanical, thermal and flow properties of polycarbonate/poly (butylene terephthalate) blends

    Science.gov (United States)

    Kumar, Ravindra; Kar, Kamal K.; Kumar, Vijai

    2018-01-01

    Bisphenol-A polycarbonate (PC) and poly(butylene terephthalate) (PBT) were melt blended with ethylene-n-butylacrylate-glycidylmethacrylate terpolymer (E-BA-GMA) at various proportions in order to study the effects of compatibilizers on mechanical, thermal and flow properties of blends. Furthermore, on the basis of this study, PC and PBT were melt-blended at 60/40 proportion with three different compatibilizers viz., ethylene-n-butylacrylate copolymer (E-BA), E-BA-GMA and random copolymer of ethylene and glycidylmethacrylate (E-GMA) at 3 phr loading in a co-rotating twin screw extruder. Tensile, flexural and impact tests were carried out on injection molded samples of PC/PBT blends. The notched izod impact strength increases enormously (˜2-3 times) on addition of any one of the three compatibilizers, and elongation at break (%) also improves tremendously (3, 5 and 4 times) on incorporation of E-BA, E-BA-GMA and E-GMA copolymer, respectively while other mechanical properties decreases slightly (3%-8%) on addition of any one of these compatibilizers. The heat deflection temperature (HDT) raises ˜8 °C-9 °C on addition of either E-BA-GMA or E-GMA, while E-BA shows a negative effect on HDT. The melt flow index diminishes significantly (˜5%-20%) on incorporation of these compatibilizers. The morphology studies via scanning electron microscopy of these four blends were carried out to confirm the mechanical results.

  18. Clinical Evaluation of an Acrylic Pontic ’Adhesively’ Bonded to Uncut Abutment Teeth: 18 Month Results

    Science.gov (United States)

    1974-12-23

    in greater detail by a dental manufacturerI0 advocates the use of a composite Bis -GMA resin+ to "ad- hesively" bond an acrylic pontic directly to...interface between the pontic and Bis -GMA resin used to cement the pontic to the natural teeth. This consistent mode of failure suggested that an...examination of the failed "bridges" showed that delamination occurred at the interface between the pontic and Bis -GMA resin used to cement the pontic to the

  19. Altered ion transport in normal human bronchial epithelial cells following exposure to chemically distinct metal welding fume particles

    Energy Technology Data Exchange (ETDEWEB)

    Fedan, Jeffrey S., E-mail: jsf2@cdc.gov; Thompson, Janet A.; Meighan, Terence G.; Zeidler-Erdely, Patti C.; Antonini, James M.

    2017-07-01

    Welding fume inhalation causes pulmonary toxicity, including susceptibility to infection. We hypothesized that airway epithelial ion transport is a target of fume toxicity, and investigated the effects of fume particulates from manual metal arc-stainless steel (MMA-SS) and gas metal arc-mild steel (GMA-MS) on ion transport in normal human bronchial epithelium (NHBE) cultured in air-interface. MMA-SS particles, more soluble than GMA-MS particles, contain Cr, Ni, Fe and Mn; GMA-MS particles contain Fe and Mn. MMA-SS or GMA-MS particles (0.0167–166.7 μg/cm{sup 2}) were applied apically to NHBEs. After 18 h transepithelial potential difference (V{sub t}), resistance (R{sub t}), and short circuit current (I{sub sc}) were measured. Particle effects on Na{sup +} and Cl¯ channels and the Na{sup +},K{sup +},2Cl¯-cotransporter were evaluated using amiloride (apical), 5-nitro-2-[(3-phenylpropyl)amino]benzoic acid (NPPB, apical), and bumetanide (basolateral), respectively. MMA-SS (0.0167–16.7 μg/cm{sup 2}) increased basal V{sub t}. Only 16.7 μg/cm{sup 2} GMA-MS increased basal V{sub t} significantly. MMA-SS or GMA-MS exposure potentiated I{sub sc} responses (decreases) to amiloride and bumetanide, while not affecting those to NPPB, GMA-MS to a lesser degree than MMA-SS. Variable effects on R{sub t} were observed in response to amiloride, and bumetanide. Generally, MMA-SS was more potent in altering responses to amiloride and bumetanide than GMA-MS. Hyperpolarization occurred in the absence of LDH release, but decreases in V{sub t}, R{sub t}, and I{sub sc} at higher fume particulate doses accompanied LDH release, to a greater extent for MMA-SS. Thus, Na{sup +} transport and Na{sup +},K{sup +},2Cl¯-cotransport are affected by fume exposure; MMA-MS is more potent than GMA-MS. Enhanced Na{sup +} absorption and decreased airway surface liquid could compromise defenses against infection. - Highlights: • Welding fume particle toxicity was investigated in human bronchial

  20. Determinación de la profundidad de curado y propiedades mecánicas de composites dentales fotopolimerizables experimentales

    OpenAIRE

    Veranes-Pantoja, Yaimarilis; Autran-Mateu, Fernando; Álvarez-Brito, Rubén; Gil-Mur, Francisco Javier

    2005-01-01

    En el presente trabajo se estudian la resistencia a la compresión, módulo en compresión, resistencia a la compresión diametral, dureza, desgaste y profundidad de curado de seis formulaciones de composites dentales fotopolimerizables. Los composites fueron preparados usando como matrices combinaciones de Bis-GMA/DMATEEG, Bis-GMA/MPS, Bis-GMA/DMATEEG/MPS. Como relleno se utilizó cuarzo del yacimiento "El Cacahual" y la combinación de cuarzo/aerosil 200. La resina VenusTM Heraus Kulzer fue utili...

  1. Cockle Field Caging Experiment Data (2014)

    Data.gov (United States)

    U.S. Environmental Protection Agency — To determine whether differences in cockle density or qualitative burial depth observed during the 2014 field survey were affected by green macroalgal (GMA) mats, we...

  2. Het belang van krimp en krimpspanning: effecten tijdens de verharding van composieten

    NARCIS (Netherlands)

    Kleverlaan, C.J.; Jongsma, L.A.

    2015-01-01

    De basis van de meeste tandheelkundige composieten bestaat uit monomeren zoals bisfenol-A diglycidylether methacrylaat (Bis-GMA) en tri-ethyleenglycoldimethacrylaat (TEGDMA), gecombineerd met vuldeeltjes van verschillende grootte en samenstelling. Tijdens het verharden met de lamp worden de

  3. GLYCOL METHACRYLATE EMBEDDING OF ALGINATE-POLYLYSINE MICROENCAPSULATED PANCREATIC-ISLETS

    NARCIS (Netherlands)

    FRITSCHY, WM; GERRITS, PO; WOLTERS, GHJ; PASMA, A; VANSCHILFGAARDE, R

    A method for processing and embedding alginate-polylysine microencapsulated pancreatic tissue in glycol methacrylate resin (GMA) is described. Fixation in 4% phosphate buffered formaldehyde, processing in ascending concentrations of glycol methacrylate monomer and embedding in Technovit 7100 results

  4. 聚合物微球固载的N-羟基邻苯二甲酰亚胺在分子氧氧化苯甲醇反应过程中的催化特性%Catalytic characteristics of N-hydroxyphthalimide immobilized on polymer microspheres in oxidation of benzyl alcohol by molecular oxygen

    Institute of Scientific and Technical Information of China (English)

    杨晓林; 黄建龙; 高保娇; 门吉英

    2015-01-01

    以甲基丙烯酸缩水甘油酯(GMA)和甲基丙烯酸甲酯(MMA)的交联共聚微球 GMA/MMA 为基质,经过几步大分子反应在微球表面合成与固载了 N-羟基邻苯二甲酰亚胺(NHPI),形成固载有 NHPI 的聚合物微球GMA/MMA-NHPI。将 GMA/MMA-NHPI 与 Co(OAc)2组成共催化体系,用于分子氧氧化苯甲醇的反应过程。研究结果表明,GMA/MMA-NHPI与Co(OAc)2所构成的共催化体系在温和条件(65℃和常压氧气)下可有效地实现苯甲醇的分子氧氧化过程,将其深度氧化为苯甲酸,显示出较好的催化活性和高的选择性(苯甲酸的选择性为96%)。主催化剂GMA/MMA-NHPI固载的NHPI与助催化剂Co(OAc)2适宜的摩尔比为20:1;主催化剂所含NHPI的摩尔分数为底物的10%时催化剂的用量比较适宜。固体催化剂GMA/MMA-NHPI还具有良好的再循环使用性能。%Crosslinked polymeric microspheres GMA/MMA of glycidyl methacrylate (GMA) and methyl methacrylate (MMA) were prepared, and then N-hydroxyphthalimide (NHPI) was synthesized and immobilized on GMA/MMA microspheres through several polymer reaction steps, resulting in the functionalized microspheres GMA/MMA-NHPI. The solid catalyst GMA/MMA-NHPI in combination with Co(OAc)2 was used in aerobic oxidation of benzyl alcohol. Experimental results showed that the composite catalyst consisting of GMA/MMA-NHPI and Co(OAc)2 could effectively catalyze aerobic oxidation of benzyl alcohol by molecular oxygen under mild conditions (65℃ and normal pressure). Benzyl alcohol was deeply oxidized to benzoic acid. Although benzyl alcohol conversion rate was not very high, catalytic activity was satisfactory and benzoic acid selectivity was as high as 96%. The appropriate molar ratio of immobilized NHPI on GMA/MMA-NHPI microspheres to Co(OAc)2 was 20:1, and the appropriate amount of GMA/MMA-NHPI was 10% (mol) of the substrate. The solid catalyst GMA/MMA-NHPI microspheres showed good recycling and reusing

  5. Research of Jiles-Atherton Dynamic Model in Giant Magnetostrictive Actuator

    Directory of Open Access Journals (Sweden)

    Yongguang Liu

    2016-01-01

    Full Text Available Due to the existence of multicoupled nonlinear factors in the giant magnetostrictive actuator (GMA, building precise mathematical model is highly important to study GMA’s characteristics and control strategies. Minor hysteresis loops near the bias magnetic field would be often applied because of its relatively good linearity. Load, friction, and disc spring stiffness seriously affect the output characteristics of the GMA in high frequency. Therefore, the current-displacement dynamic minor loops mathematical model coupling of electric-magnetic-machine is established according to Jiles-Atherton (J-A dynamic model of hysteresis material, GMA structural dynamic equation, Ampere loop circuit law, and nonlinear piezomagnetic equation and demonstrates its correctness and effectiveness in the experiments. Finally, some laws are achieved between key structural parameters and output characteristics of GMA, which provides important theoretical foundation for structural design.

  6. Cockle/Green Macroalgae Field Survey Data (2014)

    Data.gov (United States)

    U.S. Environmental Protection Agency — To quantify any spatial or temporal variability in cockle densities with respect to in situ GMA biomass in Yaquina Bay, OR, we conducted field surveys during...

  7. Xeon Phi - A comparison between the newly introduced MIC architecture and a standard CPU through three types of problems.

    OpenAIRE

    Kristiansen, Joakim

    2016-01-01

    As Moore s law continues, processors keep getting more cores packed together on the chip. This thesis is an empirical study of the rather newly introduced Intel Many Integrated Core (IMIC) architecture found in the Intel Xeon Phi. With roughly 60 cores connected by a high performance on-die interconnect, the Intel Xeon Phi makes an interesting candidate for High Performance Computing. By digging into parallel algorithms solving three well known problems, our goal is to optimize, test and comp...

  8. Limited tender notification for the AMC of desktop computers and

    Indian Academy of Sciences (India)

    Brand. 1 INTEL 82945 EXPRESS. P4 3.0GHZ. 1X2GB + 1 x 1 GB =3GB. DDR2. 160 GB STATA. WINDOWS 7 PRO SP1. 32BIT. CD/ DVDRW. 17 " LCD. 2 INTEL G31PR. PENTIUM DUAL E2160. 1.8GHZ. 2X2GB =4GB DDR2. 160 GB STATA. WINDOWS 7 PRO SP1. 32BIT. CD/ DVDRW. 17 " LCD. 3 INTEL G31/33 EXPRESS.

  9. Proceedings of the Workshop on Future Directions in Computer Architecture and Software, Held in Charleston, South Carolina on 5-7 May 1986,

    Science.gov (United States)

    1986-08-30

    the Intel /Caltech Cosmic Cube8 ; (6) massive SIMD array processors , such as the 11 Gflop IBM GFii 9 , built specifically for physics quark modelling...randomly between 0 and 100 msec. a separate communication processor ( Intel 80186) associ- (or 0 to 80 message-interaction times). In this case, in-line a...machine was announced by IMS Associates. % o The processors were Intel 8080’s. In 1983 a working hypercube, the 64-node Cosmic Cube, was demonstrated at

  10. A Computer Program to Model Passive Acoustic Antisubmarine Search Using Monte Carlo Simulation Techniques.

    Science.gov (United States)

    1983-09-01

    duplicate a continuous function on a digital computer, and thus the machine representatic- of the GMA is only a close approximation of the continuous...error process. Thus, the manner in which the GMA process is digitally replicated has an effect on the results of the simulation. The parameterization of...Information Center 2 Cameron Station Alexandria, Virginia 22314 2. Libary , Code 0142 2 Naval Postgraduate School Monterey, California 93943 3. Professor

  11. Considering space weather forces interaction on human health: the equilibrium paradigm in clinical cosmobiology - is it equal?

    Science.gov (United States)

    Stoupel, Eliyahu

    2015-03-01

    We are constantly affected by changes in space weather. The principal "players" are solar activity (SA), geomagnetic activity (GMA) and antagonistic to them, cosmic ray activity (CRA) and high energy proton flux. CRA is measured by neutron activity on the earth's surface in imp/min. SA and GMA are linked and serve as a shield for the earth from CRA. For a long time SA and GMA were the main areas of studies. The aim of this study was to compare some effects of the mentioned forces and discuss the temporal distribution of both groups of space weather, in relation to their effects on humans. The time distribution of GMA storms (daily) was compared with quiet (low) GMA, with higher CRA (neutron activity). Space weather data were obtained from the USA, Russia and Finland. A total of 4383 days were analyzed in the years 2000-2012. A total of 71 days (1.62%) of geomagnetic storms (GS) and 2753 days (63.8%) of quiet (I0) GMA were registered. A second study was provided including the years 1983-2007 (9131 days); here 3800 days (41.62%) were quiet GMA days and 400 storm days (4.38%). According to publications in the medical literature, many phenomena are connected with the extremes of space weather. Despite a great number of publications and the significant role of GS, it is a relatively rare event and most medical emergencies and deaths occur on days of low GMA, accompanied by higher CRA (neutron activity). High neutron activity deserves more attention when analyzing space effects on human health and their mechanism of action.

  12. A meta-analysis of the relationship between general mental ability and nontask performance.

    Science.gov (United States)

    Gonzalez-Mulé, Erik; Mount, Michael K; Oh, In-Sue

    2014-11-01

    Although one of the most well-established research findings in industrial-organizational psychology is that general mental ability (GMA) is a strong and generalizable predictor of job performance, this meta-analytically derived conclusion is based largely on measures of task or overall performance. The primary purpose of this study is to address a void in the research literature by conducting a meta-analysis to determine the direction and magnitude of the correlation of GMA with 2 dimensions of nontask performance: counterproductive work behaviors (CWB) and organizational citizenship behaviors (OCB). Overall, the results show that the true-score correlation between GMA and CWB is essentially 0 (-.02, k = 35), although rating source of CWB moderates this relationship. The true-score correlation between GMA and OCB is positive but modest in magnitude (.23, k = 43). The 2nd purpose of this study is to conduct meta-analytic relative weight analyses to determine the relative importance of GMA and the five-factor model (FFM) of personality traits in predicting nontask and task performance criteria. Results indicate that, collectively, the FFM traits are substantially more important for CWB than GMA, that the FFM traits are roughly equal in importance to GMA for OCB, and that GMA is substantially more important for task and overall job performance than the FFM traits. Implications of these findings for the development of optimal selection systems and the development of comprehensive theories of job performance are discussed along with study limitation and future research directions. (PsycINFO Database Record (c) 2014 APA, all rights reserved).

  13. Corrosion Behavior of Arc Weld and Friction Stir Weld in Al 6061-T6 Alloys

    International Nuclear Information System (INIS)

    Yoon, Byoung Hyun; Kim, Heung Ju; Chang, Woong Seong; Kweon, Young Gak

    2006-01-01

    For the evaluation of corrosion resistance of Al 6061-T6 Alloy, Tafel method and immersion test was performed with Friction Stir Weld(FSW) and Gas Metal Arc Weld(GMAW). The Tafel and immersion test results indicated that GMA weld was severely attacked compared with those of friction stir weld. It may be mainly due to the galvanic corrosion mechanism act on the GMA weld

  14. Case Summary: Settlement Reached at Middlefield-Ellis-Whisman (MEW) Study Area to Address TCE Contamination

    Science.gov (United States)

    Case summary of the first amended consent decree with Intel Corporation and Raytheon Company to address trichloroethylene (TC) contamination in residential and commercial buildings in Mountain View, California

  15. Ada Compiler Validation Summary Report: Certificate Number: 940325S1. 11341 DDC-I, DACS Sun SPARC/SunOS to 80186 Bare Ada Cross Compiler System, Version 4.6.4 Sun SPARCstation IPX = Intel iSBC 186/100 (Bare Machine)

    Science.gov (United States)

    1994-03-25

    declarations requiring more digits than SYSTEM.MAXDIGITS: C24113L..Y (14 tests) C35705L..Y (14 tests) C35706L..Y (14 tests) C35707L..Y (14 tests) 2-1...before the DACS Run-Time System (RMs) libary normally searches for na-4ime routin;, in this way one can replace the standard DACS RTS routines with...SHORTINTEGER is range -128 .. 127; type INTEGER is range -32_768 .. 32_767; type LONGINTEGER is range -2147_483_648 .. 2_147_483_647; type FLOAT is digits 6

  16. Ada Compiler Validation Summary Report: Certificate Number: 940325S1. 11348 DDC-I, DACS Sun SPARC/Solaris to 80386 PM Bare Ada Cross Compiler System, Version 4.6.4 Sun SPARCclassic = Intel iSBC 386/116 (Bare Machine)

    Science.gov (United States)

    1994-03-25

    digits than SYSTEM.MAXDIGITS: C24113L..Y (14 tests) C35705L..Y (14 tests) C35706L..Y (14 tests) C35707L..Y (14 tests) 2-1 C35708L..Y (14 tests) C35802L...MACHINE CODETYPE : REGISTERTYPE MANTISSADOC : 31 A-2 MAX_- DIGITS : 15 MAX_-INT : 9223372036854775807 MAX_-INTPLUS_1 : 9223372036854775808 MIN_ INT...words. A libary task is formed when a task object is declared at the outermost level of a package. Library tasks ame created and activated during the

  17. Estimulant la creativitat i l’esperit crític dins de l’escola a través de la robòtica i la intel·ligència artificial: un cas d’estudi al sud de l’Índia

    Directory of Open Access Journals (Sweden)

    Eduard Muntaner-Perich

    2012-01-01

    Full Text Available En el món ràpidament canviant d’avui en dia cada cop és més evident que l’èxit no està només basat en què sabem o quant sabem, sinó en la nostra habilitat per pensar i actuar de manera creativa. Malauradament, en la majoria dels casos els models d’aprenentatge tradicionals de les escoles no solen estar enfocats a desenvolupar el pensament creatiu. Aquest problema s’accentua encara més als països en vies de desenvolupament, on la creativitat ben utilitzada podria convertir-se en una eina fonamental per reduir la pobresa i en un motor important per al desenvolupament humà sostenible. Aquest article descriu un projecte pilot finançat per la Universitat de Girona, que combina innovació educativa i cooperació al desenvolupament, i que s’ha dut a terme a Shanti Bhavan, una escola rural del sud de l’Índia. El projecte, basat en la teoria del construccionisme, ha consistit en uns tallers en els quals, a través de les tecnologies de la informació i la comunicació (concretament treballant la robòtica i la intel•ligència artificial, s’ha estimulat la creativitat i l’esperit crític dels nens. A més, simultàniament i a través del joc i l’exploració, s’ha fet un reforç no formal de les assignatures que plantegen més problemes a l’Índia rural. L’objectiu a llarg termini és que aquests nens esdevinguin agents del canvi, creatius i innovadors, de les seves pròpies comunitats, i que, compromesos amb la seva realitat social, siguin capaços de proposar noves alternatives per millorar la seva qualitat de vida i engeguin projectes per crear riquesa en els diferents àmbits socials. Els resultats són sis tallers executats satisfactòriament, amb la continuació del projecte assegurada i amb el disseny d’un model que permetrà reproduir el projecte en altres indrets. Aquest article fa un resum del projecte, dels resultats, de les lliçons apreses i dels treballs futurs.

  18. Influence of Glycidyl Methacrylate Grafting on the Mechanical, Water Absorption, and Thermal Properties of Recycled High-Density Polyethylene/Rubber Seed Shell Particle Composites

    Directory of Open Access Journals (Sweden)

    Kaimeng Xu

    2016-01-01

    Full Text Available Rubber seed shell (RSS was modified by grafting treatment using glycidyl methacrylate (GMA at various concentrations. The RSS was then used to reinforce high-density polyethylene (HDPE. The effects of modification on the mechanical, water absorption, and thermal properties of the RSS/HDPE composites were studied using a mechanical testing instrument, weighing method, Vicat softening temperature (VST testing, thermogravimetry, and dynamic mechanical analysis. The results showed that the GMA grafting produced an improvement in the flexural and tensile properties of the composites. The water absorption rate of the composites also had an obvious decrease. While a slight increase in VST was found, the various concentrations of GMA showed no improvement in VST. GMA modification also could elevate the thermal stability of the composites at the initial decomposition stage. The optimum grafting concentration of GMA (2.5% led to the lowest thermal weight loss (37.07% and 26.56% during the first and second decomposition stages. The E’ values of the composites had a significant increase with the addition of GMA. There were two peaks of tan δ for the untreated samples, but the modified samples exhibited a shift in the transition peak at higher temperatures; moreover, the second peak disappeared.

  19. A Theory of Sex Differences in Technical Aptitude and Some Supporting Evidence.

    Science.gov (United States)

    Schmidt, Frank L

    2011-11-01

    In this article, I present a theory that explains the origin of sex differences in technical aptitudes. The theory takes as proven that there are no sex differences in general mental ability (GMA), and it postulates that sex differences in technical aptitude (TA) stem from differences in experience in technical areas, which is in turn based on sex differences in technical interests. Using a large data set, I tested and found support for four predictions made by this theory: (a) the construct level correlation between technical aptitude and GMA is larger for females than males, (b) the observed and true score variability of technical aptitude is greater among males than females, (c) at every level of GMA females have lower levels of technical aptitude, and (d) technical aptitude measures used as estimates of GMA for decision purposes would result in underestimation of GMA levels for girls and women. Given that GMA carries the weight of prediction of job performance, the support found for this last prediction suggests that, for many jobs, technical aptitude tests may underpredict the job performance of female applicants and employees. Future research should examine this question. © Association for Psychological Science 2011.

  20. Serum galactomannan screening for diagnosis of invasive pulmonary aspergillosis in children after stem cell transplantation or with high-risk leukemia.

    Science.gov (United States)

    Gefen, Aharon; Zaidman, Irina; Shachor-Meyouhas, Yael; Avidor, Israela; Hakim, Fahed; Weyl Ben-Arush, Myriam; Kassis, Imad

    2015-03-01

    Both transplanted and leukemia patients are at high risk (HR) for invasive pulmonary aspergillosis (IPA). Methods for rapid diagnosis are crucial. Our objective was to investigate the impact of serial serum galactomannan assay (GMA) screening on IPA diagnosis in children. Between January 2010 and December 2011, all children following stem cell transplantation (SCT) or with HR leukemia were prospectively included. Serum samples for GMA were taken once-twice weekly. Results >.5 were considered positive. Patients suspected of having IPA were stratified as possible, probable, and definite. Forty-six children (median age, 8 years) were included, 38 after SCT (32 allogeneic), 8 with HR leukemia. A total of 510 samples were taken; screening period was 1-6 months for 34 patients. GMA was negative in 28 patients, all but one without suspicion of IPA. Eighteen patients had positive GMA: while four (22%) were upgraded to probable IPA, fourteen (78%) were considered as false positives (FP), some associated with piperacillin-tazobactam treatment. GMA sensitivity and specificity were 0.8 and 0.66, respectively; positive- and negative-predictive values (PPV, NPV) were 0.22 and 0.96, respectively. GMA may have a role in evaluating HR children for IPA. Both NPV and FP rates are high. The cost benefit of early detection versus over-diagnosis should be further studied.

  1. Modification of flax fibres by radiation induced emulsion graft copolymerization of glycidyl methacrylate

    International Nuclear Information System (INIS)

    Moawia, Rihab Musaad; Nasef, Mohamed Mahmoud; Mohamed, Nor Hasimah; Ripin, Adnan

    2016-01-01

    Flax fibres were modified by radiation induced graft copolymerization of glycidyl methacrylate (GMA) by pre-irradiation method in an emulsion medium. The effect of reaction parameters on the degree of grafting (DOG) such as concentration of bleaching agent, absorbed dose, monomer concentration, temperature and reaction time were investigated. The DOG was found to be dependent on the investigated parameters. The incorporation of poly(GMA) grafts in the bleached flax fibres was confirmed by Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM). The structural and mechanical changes were evaluated by X-ray diffraction (XRD) and mechanical tester, respectively. The results revealed that reacting bleached flax fibres irradiated with 20 kGy with 5% GMA emulsion containing 0.5% polyoxyethylene-sorbitan monolaurate (Tween 20) surfactant at 40 °C for 1 h led to a maximum DOG of 148%. The grafted fibres showed sufficient mechanical strength and hydrophobicity which make them promising precursors for development of adsorbents after appropriate chemical treatments. - Highlights: • Flax fibers were modified by radiation induced emulsion grafting of GMA. • Bleaching with 0.7 wt% Na-chlorite was essential for achieving high DOGs. • Effect of reaction parameters on the degree of grafting were established. • The incorporation of poly-GMA grafts was proved by SEM, FTIR and XRD. • The obtained poly-GMA grafted flax fibers have potential for adsorbent making.

  2. Incorporation of metal-organic framework HKUST-1 into porous polymer monolithic capillary columns to enhance the chromatographic separation of small molecules.

    Science.gov (United States)

    Yang, Shengchao; Ye, Fanggui; Lv, Qinghui; Zhang, Cong; Shen, Shufen; Zhao, Shulin

    2014-09-19

    Metal-organic framework (MOF) HKUST-1 nanoparticles have been incorporated into poly(glycidyl methacrylate-co-ethylene dimethacrylate) (HKUST-1-poly(GMA-co-EDMA)) monoliths to afford stationary phases with enhanced chromatographic performance of small molecules in the reversed phase capillary liquid chromatography. The effect of HKUST-1 nanoparticles in the polymerization mixture on the performance of the monolithic column was explored in detail. While the bare poly(GMA-co-EDMA) monolith exhibited poor resolution (RsHKUST-1 nanoparticles to the polymerization mixture provide high increased resolution (Rs≥1.3) and high efficiency ranged from 16,300 to 44,300plates/m. Chromatographic performance of HKUST-1-poly(GMA-co-EDMA) monolith was demonstrated by separation of various analytes including polycyclic aromatic hydrocarbons, ethylbenzene and styrene, phenols and aromatic acids using a binary polar mobile phase (CH3CN/H2O). The HKUST-1-poly(GMA-co-EDMA) monolith displayed enhanced hydrophobic and π-π interaction characteristics in the reversed phase separation of test analytes compared to the bare poly(GMA-co-EDMA) monolith. The experiment results showed that HKUST-1-poly(GMA-co-EDMA) monoliths are an alternative to enhance the chromatographic separation of small molecules. Copyright © 2014 Elsevier B.V. All rights reserved.

  3. SiRen: Leveraging Similar Regions for Efficient and Accurate Variant Calling

    Science.gov (United States)

    2015-05-30

    Cloudera, EMC2, Ericsson, Facebook, Guavus, HP, Huawei, Informatica , Intel, Microsoft, NetApp, Pivotal, Samsung, Schlumberger, Splunk, Virdata and VMware...EMC2, Ericsson, Facebook, Guavus, HP, Huawei, Informatica , Intel, Microsoft, NetApp, Pivotal, Samsung, Schlumberger, Splunk, Virdata and VMware

  4. Locally orderless registration code

    DEFF Research Database (Denmark)

    2012-01-01

    This is code for the TPAMI paper "Locally Orderless Registration". The code requires intel threadding building blocks installed and is provided for 64 bit on mac, linux and windows.......This is code for the TPAMI paper "Locally Orderless Registration". The code requires intel threadding building blocks installed and is provided for 64 bit on mac, linux and windows....

  5. A High Performance Computing Framework for Physics-based Modeling and Simulation of Military Ground Vehicles

    Science.gov (United States)

    2011-03-25

    cluster. The co-processing idea is the enabler of the heterogeneous computing concept advertised recently as the paradigm capable of delivering exascale ...Petascale to Exascale : Extending Intel’s HPC Commitment: http://download.intel.com/pressroom/archive/reference/ISC_2010_Skaugen_keynote.pdf in

  6. Enabling Computational Dynamics in Distributed Computing Environments Using a Heterogeneous Computing Template

    Science.gov (United States)

    2011-08-09

    heterogeneous computing concept advertised recently as the paradigm capable of delivering exascale flop rates by the end of the decade. In this framework...and Lamb. Page 10 of 10 UNCLASSIFIED [3] Skaugen, K., Petascale to Exascale : Extending Intel’s HPC Commitment: http://download.intel.com

  7. Experiences implementing the MPI standard on Sandia`s lightweight kernels

    Energy Technology Data Exchange (ETDEWEB)

    Brightwell, R.; Greenberg, D.S.

    1997-10-01

    This technical report describes some lessons learned from implementing the Message Passing Interface (MPI) standard, and some proposed extentions to MPI, at Sandia. The implementations were developed using Sandia-developed lightweight kernels running on the Intel Paragon and Intel TeraFLOPS platforms. The motivations for this research are discussed, and a detailed analysis of several implementation issues is presented.

  8. Building Task-Oriented Applications: An Introduction to the Legion Programming Paradigm

    Science.gov (United States)

    2015-02-01

    Intel Corporation. Intel Xeon Phi Coprocessor Instruction Set Architecture Reference Manual, 7 Sep 2012. [accessed 2014 Jun 1]. https...algorithmic development rather than the idiosyncrasies of different computing architectures . Legion is part of a small but growing movement to treat...Multicore central processing units (CPUs) and various hardware accelerators exacerbate a complex architectural landscape that inevitably constrains

  9. The Intelcities Community of Practice: The Capacity-Building, Co-Design, Evaluation, and Monitoring of E-Government Services

    Science.gov (United States)

    Deakin, Mark; Lombardi, Patrizia; Cooper, Ian

    2011-01-01

    The paper examines the IntelCities Community of Practice (CoP) supporting the development of the organization's capacity-building, co-design, monitoring, and evaluation of e-government services. It begins by outlining the IntelCities CoP and goes on to set out the integrated model of electronically enhanced government (e-government) services…

  10. Dual-core Itanium Processor

    CERN Multimedia

    2006-01-01

    Intel’s first dual-core Itanium processor, code-named "Montecito" is a major release of Intel's Itanium 2 Processor Family, which implements the Intel Itanium architecture on a dual-core processor with two cores per die (integrated circuit). Itanium 2 is much more powerful than its predecessor. It has lower power consumption and thermal dissipation.

  11. ML-o-Scope: A Diagnostic Visualization System for Deep Machine Learning Pipelines

    Science.gov (United States)

    2014-05-16

    Huawei , Intel, Microsoft, NetApp, Pivotal, Splunk, Virdata, VMware, WANdisco and Yahoo!. ML-o-scope: a diagnostic visualization system for deep machine...Facebook, GameOnTalis, Guavus, HP, Huawei , Intel, Microsoft, NetApp, Pivotal, Splunk, Virdata, VMware, WANdisco and Yahoo!. References [1] Bruna, J., and

  12. Embedded Systems Design with 8051 Microcontrollers

    DEFF Research Database (Denmark)

    Karakahayov, Zdravko; Winther, Ole; Christensen, Knud Smed

    Textbook on embedded microcontrollers. Example microcontroller family: Intel 8051 with special emphasis on Philips 80C552. Structure, design examples and programming in C and assembler. Hardware - software codesign. EProm emulator.......Textbook on embedded microcontrollers. Example microcontroller family: Intel 8051 with special emphasis on Philips 80C552. Structure, design examples and programming in C and assembler. Hardware - software codesign. EProm emulator....

  13. 76 FR 39895 - In the Matter of Certain Microprocessors, Components Thereof, and Products Containing Same...

    Science.gov (United States)

    2011-07-07

    ... Commission Rule 210.50(b)(1), 19 CFR 210.50(b)(1), the presiding administrative law judge shall take evidence...; Intel Malaysia Sdn. Bhd, Bayan Lapas Free Trade Zone, Phase III, Penang 11900, Malaysia; Intel...; Hewlett-Packard Company, 3000 Hanover Street, Palo Alto, CA 94304. (c) The Office of Unfair Import...

  14. 78 FR 12354 - Certain Microprocessors, Components Thereof, and Products Containing Same; Termination of...

    Science.gov (United States)

    2013-02-22

    ... by accessing its Internet server ( http://www.usitc.gov ). The public record for this investigation... of Penang, Malaysia; and Intel Products (Chengdu) Ltd. of Chengdu, China (collectively, ``Intel... Commission's forthcoming opinion. The authority for the Commission's determination is contained in section...

  15. Space weather and human deaths distribution: 25 years' observation (Lithuania, 1989-2013).

    Science.gov (United States)

    Stoupel, Eliyahu G; Petrauskiene, Jadvyga; Kalediene, Ramune; Sauliune, Skirmante; Abramson, Evgeny; Shochat, Tzippy

    2015-09-01

    Human health is affected by space weather component [solar (SA), geomagnetic (GMA), cosmic ray (CRA) - neutrons, space proton flux] activity levels. The aim of this study was to check possible links between timing of human (both genders) monthly deaths distribution and space weather activity. Human deaths distribution in the Republic of Lithuania from 1989 to 2013 (25 years, i.e., 300 consecutive months) was studied, which included 1,050,503 deaths (549,764 male, 500,739 female). Pearson correlation coefficients (r) and their probabilities (p) were obtained for years: months 1-12, sunspot number, smoothed sunspot number, solar flux (2800 MGH, 10.7 cm), adjusted solar flux for SA; A, C indices of GMA; neutron activity at the earth's surface (imp/min) for CRA. The cosmophysical data were obtained from space science institutions in the USA, Russia and Finland. The mentioned physical parameters were compared with the total number of deaths, deaths from ischemic heart disease (n=376,074), stroke (n=132,020), non-cardiovascular causes (n=542,409), accidents (n=98,805), traffic accidents (n=21,261), oncology (n=193,017), diabetes mellitus (n=6631) and suicide (n=33,072). Space factors were interrelated as follows for the considered period: CRA was inversely related to SA and GMA, CRA/SA (r=-0.86, p>0.0001), CRA/GMA (r=-0.70, pweather component activity. Extreme levels of activities of both groups (SA, GMA, and opposite CRA - neutron) are related to some health risks. In the considered period, there were relatively few GMA storms and low GMA was dominating, accompanied by higher CRA (neutron) activity. The ways of action of the components of space weather on the human body need additional studies. There is a special need for the prevention of rising cerebral vascular accidents and oncology malignancies as the causes of death.

  16. Altered ion transport in normal human bronchial epithelial cells following exposure to chemically distinct metal welding fume particles.

    Science.gov (United States)

    Fedan, Jeffrey S; Thompson, Janet A; Meighan, Terence G; Zeidler-Erdely, Patti C; Antonini, James M

    2017-07-01

    Welding fume inhalation causes pulmonary toxicity, including susceptibility to infection. We hypothesized that airway epithelial ion transport is a target of fume toxicity, and investigated the effects of fume particulates from manual metal arc-stainless steel (MMA-SS) and gas metal arc-mild steel (GMA-MS) on ion transport in normal human bronchial epithelium (NHBE) cultured in air-interface. MMA-SS particles, more soluble than GMA-MS particles, contain Cr, Ni, Fe and Mn; GMA-MS particles contain Fe and Mn. MMA-SS or GMA-MS particles (0.0167-166.7μg/cm 2 ) were applied apically to NHBEs. After 18h transepithelial potential difference (V t ), resistance (R t ), and short circuit current (I sc ) were measured. Particle effects on Na + and Cl¯ channels and the Na + ,K + ,2Cl¯-cotransporter were evaluated using amiloride (apical), 5-nitro-2-[(3-phenylpropyl)amino]benzoic acid (NPPB, apical), and bumetanide (basolateral), respectively. MMA-SS (0.0167-16.7μg/cm 2 ) increased basal V t . Only 16.7μg/cm 2 GMA-MS increased basal V t significantly. MMA-SS or GMA-MS exposure potentiated I sc responses (decreases) to amiloride and bumetanide, while not affecting those to NPPB, GMA-MS to a lesser degree than MMA-SS. Variable effects on R t were observed in response to amiloride, and bumetanide. Generally, MMA-SS was more potent in altering responses to amiloride and bumetanide than GMA-MS. Hyperpolarization occurred in the absence of LDH release, but decreases in V t , R t , and I sc at higher fume particulate doses accompanied LDH release, to a greater extent for MMA-SS. Thus, Na + transport and Na + ,K + ,2Cl¯-cotransport are affected by fume exposure; MMA-MS is more potent than GMA-MS. Enhanced Na + absorption and decreased airway surface liquid could compromise defenses against infection. Published by Elsevier Inc.

  17. γ-Glutamylmethylamide Is an Essential Intermediate in the Metabolism of Methylamine by Methylocella silvestris▿

    Science.gov (United States)

    Chen, Yin; Scanlan, Julie; Song, Lijiang; Crombie, Andrew; Rahman, M. Tanvir; Schäfer, Hendrik; Murrell, J. Colin

    2010-01-01

    Methylocella silvestris BL2, a facultative methane utilizer, can grow on monomethylamine (MMA) as a sole carbon and nitrogen source. No activity of MMA dehydrogenase was detectable. Instead, this bacterium utilizes a methylated amino acid pathway (γ-glutamylmethylamide [GMA] and N-methylglutamate [NMG]) for MMA metabolism. The activities of the two key enzymes in this pathway, GMA synthetase and NMG dehydrogenase, were found when the bacterium was grown on MMA. GMA was detected by high-performance liquid chromatography-mass spectrometry only when the bacterium was grown on MMA but not when it was grown on methanol. Proteomic analysis of soluble and membrane fractions of the proteome from MMA- and methanol-grown cultures revealed that an eight-gene cluster (Msil2632 to Msil2639) was induced by MMA and cotranscribed as an operon, as shown by reverse transcription-PCR. GMA-dissimilating enzyme activity was also detected when it was grown on MMA. Formaldehyde and ammonium production from GMA was dependent on glutamate but not on α-ketoglutarate. Marker exchange mutagenesis of a putative GMAS gene homologue (gmas, Msil2635) within this eight-gene cluster, with a kanamycin gene cassette, abolished growth of M. silvestris on MMA as either a sole carbon or a sole nitrogen source. Overall, our results suggest that gmas is essential in MMA metabolism by M. silvestris. PMID:20472738

  18. {gamma}-Glutamylmethylamide is an essential intermediate in the metabolism of methylamine by Methylocella silvestris.

    Science.gov (United States)

    Chen, Yin; Scanlan, Julie; Song, Lijiang; Crombie, Andrew; Rahman, M Tanvir; Schäfer, Hendrik; Murrell, J Colin

    2010-07-01

    Methylocella silvestris BL2, a facultative methane utilizer, can grow on monomethylamine (MMA) as a sole carbon and nitrogen source. No activity of MMA dehydrogenase was detectable. Instead, this bacterium utilizes a methylated amino acid pathway (gamma-glutamylmethylamide [GMA] and N-methylglutamate [NMG]) for MMA metabolism. The activities of the two key enzymes in this pathway, GMA synthetase and NMG dehydrogenase, were found when the bacterium was grown on MMA. GMA was detected by high-performance liquid chromatography-mass spectrometry only when the bacterium was grown on MMA but not when it was grown on methanol. Proteomic analysis of soluble and membrane fractions of the proteome from MMA- and methanol-grown cultures revealed that an eight-gene cluster (Msil2632 to Msil2639) was induced by MMA and cotranscribed as an operon, as shown by reverse transcription-PCR. GMA-dissimilating enzyme activity was also detected when it was grown on MMA. Formaldehyde and ammonium production from GMA was dependent on glutamate but not on alpha-ketoglutarate. Marker exchange mutagenesis of a putative GMAS gene homologue (gmas, Msil2635) within this eight-gene cluster, with a kanamycin gene cassette, abolished growth of M. silvestris on MMA as either a sole carbon or a sole nitrogen source. Overall, our results suggest that gmas is essential in MMA metabolism by M. silvestris.

  19. The influence of individual and team cognitive ability on operators' task and safety performance: a multilevel field study in nuclear power plants.

    Directory of Open Access Journals (Sweden)

    Jingyu Zhang

    Full Text Available While much research has investigated the predictors of operators' performance such as personality, attitudes and motivation in high-risk industries, its cognitive antecedents and boundary conditions have not been fully investigated. Based on a multilevel investigation of 312 nuclear power plant main control room operators from 50 shift teams, the present study investigated how general mental ability (GMA at both individual and team level can influence task and safety performance. At the individual level, operators' GMA was predictive of their task and safety performance and this trend became more significant as they accumulated more experience. At the team level, we found team GMA had positive influences on all three performance criteria. However, we also found a "big-fish-little-pond" effect insofar as team GMA had a relatively smaller effect and inhibited the contribution of individual GMA to workers' extra-role behaviors (safety participation compared to its clear beneficial influence on in-role behaviors (task performance and safety compliance. The possible mechanisms related to learning and social comparison processes are discussed.

  20. The influence of individual and team cognitive ability on operators' task and safety performance: a multilevel field study in nuclear power plants.

    Science.gov (United States)

    Zhang, Jingyu; Li, Yongjuan; Wu, Changxu

    2013-01-01

    While much research has investigated the predictors of operators' performance such as personality, attitudes and motivation in high-risk industries, its cognitive antecedents and boundary conditions have not been fully investigated. Based on a multilevel investigation of 312 nuclear power plant main control room operators from 50 shift teams, the present study investigated how general mental ability (GMA) at both individual and team level can influence task and safety performance. At the individual level, operators' GMA was predictive of their task and safety performance and this trend became more significant as they accumulated more experience. At the team level, we found team GMA had positive influences on all three performance criteria. However, we also found a "big-fish-little-pond" effect insofar as team GMA had a relatively smaller effect and inhibited the contribution of individual GMA to workers' extra-role behaviors (safety participation) compared to its clear beneficial influence on in-role behaviors (task performance and safety compliance). The possible mechanisms related to learning and social comparison processes are discussed.

  1. Iminodiacetic acid functionalised organopolymer monoliths: application to the separation of metal cations by capillary high-performance chelation ion chromatography.

    Science.gov (United States)

    Moyna, Áine; Connolly, Damian; Nesterenko, Ekaterina; Nesterenko, Pavel N; Paull, Brett

    2013-03-01

    Lauryl methacrylate-co-ethylene dimethacrylate monoliths were polymerised within fused silica capillaries and subsequently photo-grafted with varying amounts of glycidyl methacrylate (GMA). The grafted monoliths were then further modified with iminodiacetic acid (IDA), resulting in a range of chelating ion-exchange monoliths of increasing capacity. The IDA functional groups were attached via ring opening of the epoxy group on the poly(GMA) structure. Increasing the amount of attached poly(GMA), via photo-grafting with increasing concentrations of GMA, from 15 to 35%, resulted in a proportional and controlled increase in the complexation capacity of the chelating monoliths. Scanning capacitively coupled contactless conductivity detection (sC(4)D) was used to characterise and verify homogenous distribution of the chelating ligand along the length of the capillaries non-invasively. Chelation ion chromatographic separations of selected transition and heavy metals were carried out, with retention factor data proportional to the concentration of grafted poly(GMA). Average peak efficiencies of close to 5,000 N/m were achieved, with the isocratic separation of Na, Mg(II), Mn(II), Co(II), Cd(II) and Zn(II) possible on a 250-mm-long monolith. Multiple monolithic columns produced to the same recipes gave RSD data for retention factors of ions). The monolithic chelating ion-exchanger was applied to the separation of alkaline earth and transition metal ions spiked in natural and potable waters.

  2. Computer-based video analysis identifies infants with absence of fidgety movements.

    Science.gov (United States)

    Støen, Ragnhild; Songstad, Nils Thomas; Silberg, Inger Elisabeth; Fjørtoft, Toril; Jensenius, Alexander Refsum; Adde, Lars

    2017-10-01

    BackgroundAbsence of fidgety movements (FMs) at 3 months' corrected age is a strong predictor of cerebral palsy (CP) in high-risk infants. This study evaluates the association between computer-based video analysis and the temporal organization of FMs assessed with the General Movement Assessment (GMA).MethodsInfants were eligible for this prospective cohort study if referred to a high-risk follow-up program in a participating hospital. Video recordings taken at 10-15 weeks post term age were used for GMA and computer-based analysis. The variation of the spatial center of motion, derived from differences between subsequent video frames, was used for quantitative analysis.ResultsOf 241 recordings from 150 infants, 48 (24.1%) were classified with absence of FMs or sporadic FMs using the GMA. The variation of the spatial center of motion (C SD ) during a recording was significantly lower in infants with normal (0.320; 95% confidence interval (CI) 0.309, 0.330) vs. absence of or sporadic (0.380; 95% CI 0.361, 0.398) FMs (P<0.001). A triage model with C SD thresholds chosen for sensitivity of 90% and specificity of 80% gave a 40% referral rate for GMA.ConclusionQuantitative video analysis during the FMs' period can be used to triage infants at high risk of CP to early intervention or observational GMA.

  3. Syntheses of amine-type adsorbents with emulsion graft polymerization of glycidyl methacrylate

    International Nuclear Information System (INIS)

    Seko, N.; Bang, L.T.; Tamada, M.

    2007-01-01

    Glycidyl methacrylate (GMA) which was precursor monomer for the synthesis of metal ion adsorbent was emulsified by surfactant of Tween 20 (Tw-20). The emulsion of 5% GMA in the water was stable for 48 h at Tw-20 concentration of 0.5%. Graft polymerization of GMA on polyethylene fiber was carried out in the emulsion state at various pre-irradiation doses. Degree of grafting (Dg) reached 103%, 301% and 348% for 1 h grafting at 40 deg. C with pre-irradiation of 10, 30 and 40 kGy, respectively. But the Dg was depressed when the pre-irradiation dose was over 50 kGy since cross-linking occurred simultaneously in the trunk polymer. Dg decreased with increment of Tw-20 concentration in emulsion of 5% GMA at pre-irradiation of 40 kGy. The three kinds of amine-type adsorbents were synthesized by reacting diethylenetriamine (DETA), triethylenetetramine (TETA) and ethylenediamine (EDA) with GMA-grafted polyethylene fiber. The synthesized EDA-type adsorbent had the highest selectivity against U ion and the distribution coefficient was 2.0 x 10 6

  4. Supertoughened renewable PLA reactive multiphase blends system: phase morphology and performance.

    Science.gov (United States)

    Zhang, Kunyu; Nagarajan, Vidhya; Misra, Manjusri; Mohanty, Amar K

    2014-08-13

    Multiphase blends of poly(lactic acid) (PLA), ethylene-methyl acrylate-glycidyl methacrylate (EMA-GMA) terpolymer, and a series of renewable poly(ether-b-amide) elastomeric copolymer (PEBA) were fabricated through reactive melt blending in an effort to improve the toughness of the PLA. Supertoughened PLA blend showing impact strength of ∼500 J/m with partial break impact behavior was achieved at an optimized blending ratio of 70 wt % PLA, 20 wt % EMA-GMA, and 10 wt % PEBA. Miscibility and thermal behavior of the binary blends PLA/PEBA and PLA/EMA-GMA, and the multiphase blends were also investigated through differential scanning calorimetric (DSC) and dynamic mechanical analysis (DMA). Phase morphology and fracture surface morphology of the blends were studied through scanning electron microscopy (SEM) and atomic force microscopy (AFM) to understand the strong corelation between the morphology and its significant effect on imparting tremendous improvement in toughness. A unique "multiple stacked structure" with partial encapsulation of EMA-GMA and PEBA minor phases was observed for the PLA/EMA-GMA/PEBA (70/20/10) revealing the importance of particular blend composition in enhancing the toughness. Toughening mechanism behind the supertoughened PLA blends have been established by studying the impact fractured surface morphology at different zones of fracture. Synergistic effect of good interfacial adhesion and interfacial cavitations followed by massive shear yielding of the matrix was believed to contribute to the enormous toughening effect observed in these multiphase blends.

  5. Thin-film type Li-ion battery, using a polyethylene separator grafted with glycidyl methacrylate

    International Nuclear Information System (INIS)

    Ko, J.M.; Min, B.G.; Kim, D.-W.; Ryu, K.S.; Kim, K.M.; Lee, Y.G.; Chang, S.H.

    2004-01-01

    For the improvement of organic electrolyte holding ability, the hydrophobic surface of a porous polyethylene (PE)-membrane separator was modified by grafting a hydrophilic monomer, glycidyl methacrylate (GMA), PE-g-GMA, by using electron beam technology, and applied to a thin film type Li-ion battery to elucidate the effect of a surface modification of a PE membrane separator on the cyclic life of Li-ion batteries. The Li-ion battery using the PE-g-GMA membrane separator showed a better cycle life than that of the unmodified PE membrane separator, indicating that the surface hydrophilicity of the PE membrane separator improved the electrolyte holding capability between the electrodes in the Li-ion cell and prevented the electrolyte leakage

  6. Bias Magnetic Field of Stack Giant Magnetostrictive Actuator: Design, Analysis, and Optimization

    Directory of Open Access Journals (Sweden)

    Zhaoshu Yang

    2016-01-01

    Full Text Available Many novel applications using giant magnetostrictive actuators (GMA require their actuators output bidirectional strokes to be large enough to drive the load. In these cases, the sophisticated method to form such a sufficient bias field with minimum power and bulk consumption should be considered in the principal stage of GMA design. This paper concerns the methodology of bias field design for a specific GMA with stack PMs and GMMs (SGMA: both loop and field models for its bias field are established; the optimization method for given SGMA structure is outlined; a prototype is fabricated to verify the theory. Simulation and test results indicate that the bias field could be exerted more easily using SGMA structure; the modeling and optimization methodology for SGMA is valid in practical design.

  7. Efficacy and safety of granulocyte, monocyte/macrophage adsorptive in pediatric ulcerative colitis

    DEFF Research Database (Denmark)

    Ruuska, Tarja; Küster, Peter; Grahnquist, Lena

    2016-01-01

    AIM: To investigate efficacy and safety for granulocyte, monocyte apheresis in a population of pediatric patients with ulcerative colitis. METHODS: The ADAPT study was a prospective, open-label, multicenter study in pediatric patients with moderate, active ulcerative colitis with pediatric...... ulcerative colitis activity index (PUCAI) of 35-64. Patients received one weekly apheresis with Adacolumn(®) granulocyte, monocyte/macrophage adsorptive (GMA) apheresis over 5 consecutive weeks, optionally followed by up to 3 additional apheresis treatments over 3 consecutive weeks. The primary endpoint...... mg daily on average from Baseline to week 12. CONCLUSION: Adacolumn(®) GMA apheresis treatment was effective in pediatric patients with moderate active Ulcerative Colitis. No new safety signals were reported. The present data contribute to considering GMA apheresis as a therapeutic option...

  8. Study on grafting glycidyl methacrylate onto HDPE membranes by pre-irradiation graft copolymerization

    International Nuclear Information System (INIS)

    Tong Long; Zu Jianhua; Liu Xinwen; Sun Guisheng; Yu Chunhui

    2006-01-01

    Glycidyl methacrylate (GMA) was grafted onto HDPE membranes by pre-irradiation method with 1.8 MeV E-beam and a kind of membranes having reactive epoxy groups was successfully synthesized. Effects of monomer concentration, reaction temperature and time and irradiation dose on the grafting yield were studied. Composition, thermo-property and surface morphology of the grafted membranes were studied by FTIR, DSC and Tapping-mode AFM, respectively. The FTIR measurements proved the synthesized copolymer is HDPE-g-GMA. The DSC results indicated the grafted HDPE's melting temperature (T m ) and heat of fusion (ΔH f ( HDPE) ) which was reduced with increasing grafting yield. The AFM images indicated that surface of the HDPE-g-GMA membranes was rougher than the virgin HDPE. (authors)

  9. AFM study of the morphologic change of HDPE surface photografted with glycidyl methacrylate.

    Science.gov (United States)

    Wang, Huiliang; Han, Jianmei

    2009-05-01

    The UV-induced grafting of glycidyl methacrylate (GMA) onto high-density polyethylene (HDPE) and the atomic force microscopy (AFM) study of the morphologic change of the grafted surface are reported. The grafting was carried out in GMA acetone solutions with different monomer concentrations. Grafting was much faster in a solution with a higher monomer concentration. FTIR analyses proved that GMA had been successfully grafted onto HDPE. The morphologies of grafted HDPE surfaces changed with UV irradiation time. The monomer concentration had a significant effect on the morphologies of the grafted HDPE surfaces. The HDPE surface grafted in a solution with a higher monomer concentration was much rougher than that grafted in a solution with a lower monomer concentration. The growth models of the grafted granules or clusters are also proposed.

  10. Effect of compatibilizer on impact and morphological analysis of recycled HDPE/PET blends

    Energy Technology Data Exchange (ETDEWEB)

    Salleh, Mohd Nazry [School of Applied Physics, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia and School of Materials Engineering, Universiti Malaysia Perlis, 02600 Jejawi, Perlis (Malaysia); Ahmad, Sahrim; Ghani, Mohd Hafizuddin Ab; Chen, Ruey Shan [School of Applied Physics, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor (Malaysia)

    2013-11-27

    Blends based on recycled high density polyethylene (rHDPE) and recycled polyethylene terephthalate (rPET) were prepared using a corotating twin screw extruder. PET and HDPE are incompatible polymers and their blends showed poor properties. Compatibilization is a step to obtain blends with good mechanical properties and in this work, ethylene glycidyl methacrylate copolymer (E-GMA) was used as a compatibilizing agent. The effect of blends based on rHDPE and rPET with and without a compatibilizer, E-GMA were examined. From the studies clearly showed that the addition of 5% E-GMA increased the impact strength. SEM analysis of rHDPE/rPET blends confirmed the morphological interaction and improved interfacial bonding between two phases.

  11. Motor-Driven Giant Magnetostrictive Actuator

    DEFF Research Database (Denmark)

    Zhang, Lihui; Xia, Yongming; Lu, Kaiyuan

    2015-01-01

    A typical giant magnetostrictive actuator (GMA) expands a magnetostrictive rod to generate strain by varying the current in the coil that surrounds the magnetostrictive rod. The heat generated by the current deteriorates the GMA performance. In particular, a constant current in the coil is required....... The magnetic field in the iron-gallium alloy (Galfenol), which is a type of magnetostrictive material, is periodically altered by rotating the permanent magnets instead of varying the coil current in the traditional GMA. The proposed MDGMA not only achieves continuous adjustment of the output strain, but can...... also maintain a constant output strain without consuming any power. In addition, the coil-free design releases the new MDGMA from the heat generated by the excitation coil, which allows the MDGMA to work more stably....

  12. Bisphenol A in dental sealants and its estrogen like effect

    Directory of Open Access Journals (Sweden)

    Manu Rathee

    2012-01-01

    Full Text Available Bisphenol A or BPA-based epoxy resins are widely used in the manufacture of commercial products, including dental resins, polycarbonate plastics, and the inner coating of food cans. BPA is a precursor to the resin monomer Bis-GMA. During the manufacturing process of Bis-GMA dental sealants, Bisphenol A (BPA might be present as an impurity or as a degradation product of Bis-DMA through esterases present in saliva. Leaching of these monomers from resins can occur during the initial setting period and in conjunction with fluid sorption and desorption over time and this chemical leach from dental sealants may be bioactive. Researchers found an estrogenic effect with BPA, Bis-DMA, and Bis-GMA because BPA lacks structural specificity as a natural ligand to the estrogen receptor. It generated considerable concern regarding the safety of dental resin materials. This review focuses on the BPA in dental sealants and its estrogen-like effect.

  13. Inhalation of gas metal arc-stainless steel welding fume promotes lung tumorigenesis in A/J mice.

    Science.gov (United States)

    Falcone, Lauryn M; Erdely, Aaron; Meighan, Terence G; Battelli, Lori A; Salmen, Rebecca; McKinney, Walter; Stone, Samuel; Cumpston, Amy; Cumpston, Jared; Andrews, Ronnee N; Kashon, Michael; Antonini, James M; Zeidler-Erdely, Patti C

    2017-08-01

    Epidemiologic studies suggest an increased risk of lung cancer with exposure to welding fumes, but controlled animal studies are needed to support this association. Oropharyngeal aspiration of collected "aged" gas metal arc-stainless steel (GMA-SS) welding fume has been shown by our laboratory to promote lung tumor formation in vivo using a two-stage initiation-promotion model. Our objective in this study was to determine whether inhalation of freshly generated GMA-SS welding fume also acts as a lung tumor promoter in lung tumor-susceptible mice. Male A/J mice received intraperitoneal (IP) injections of corn oil or the chemical initiator 3-methylcholanthrene (MCA; 10 µg/g) and 1 week later were exposed by whole-body inhalation to air or GMA-SS welding aerosols for 4 h/d × 4 d/w × 9 w at a target concentration of 40 mg/m 3 . Lung nodules were enumerated at 30 weeks post-initiation. GMA-SS fume significantly promoted lung tumor multiplicity in A/J mice initiated with MCA (16.11 ± 1.18) compared to MCA/air-exposed mice (7.93 ± 0.82). Histopathological analysis found that the increased number of lung nodules in the MCA/GMA-SS group were hyperplasias and adenomas, which was consistent with developing lung tumorigenesis. Metal deposition analysis in the lung revealed a lower deposited dose, approximately fivefold compared to our previous aspiration study, still elicited a significant lung tumorigenic response. In conclusion, this study demonstrates that inhaling GMA-SS welding fume promotes lung tumorigenesis in vivo which is consistent with the epidemiologic studies that show welders may be at an increased risk for lung cancer.

  14. Rheological and mechanical properties of polyamide 6 modified by electron-beam initiated mediation process

    International Nuclear Information System (INIS)

    Shin, Boo Young; Kim, Jae Hong

    2015-01-01

    Polyamide (PA6) has been modified by electron-beam initiated mediator process to improve drawbacks of PA6. Glycidyl methacrylate (GMA) was chosen as a reactive mediator for modification process of PA6. The mixture of the PA6 and GMA was prepared by using a twin-screw extruder, and then the mixture was exposed to electron-beam irradiation at various doses at room temperature. The modified PA6 were characterized by observing rheological and mechanical properties and compared virgin PA6. Thermal properties, water absorption, and gel fraction were also investigated. Tight gel was not found even when PA6 was irradiated at 200 kGy. Complex viscosity and storage modulus of PA6 were remarkably increased by electron-beam irradiation with medium of GMA. Maximum increase in complex viscosity was 75 times higher than virgin PA6 at 0.1 rad/s when it was irradiated at 200 kGy with the GMA. Mechanical properties were also improved without scarifying of processability. The reaction mechanisms for the mediation process with the reactive mediator of GMA were estimated to elucidate the cause of significantly enhanced rheological and mechanical properties without loss of thermoplasticity. - Highlights: • PA6 was modified by the electron-beam initiated mediation process. • Maximum increase in complex viscosity of modified PA6 was 75 times higher than virgin PA6 at 0.1 rad/s. • Mechanical properties were improved without scarifying of processability. • The GMA as a mediator played a key role in the electron-beam initiated mediation process

  15. Fibrous polymer grafted magnetic chitosan beads with strong poly(cation-exchange) groups for single step purification of lysozyme.

    Science.gov (United States)

    Bayramoglu, Gulay; Tekinay, Turgay; Ozalp, V Cengiz; Arica, M Yakup

    2015-05-15

    Lysozyme is an important polypetide used in medical and food applications. We report a novel magnetic strong cation exchange beads for efficient purification of lysozyme from chicken egg white. Magnetic chitosan (MCHT) beads were synthesized via phase inversion method, and then grafted with poly(glycidyl methacrylate) (p(GMA)) via the surface-initiated atom transfer radical polymerization (SI-ATRP). Epoxy groups of the grafted polymer, were modified into strong cation-exchange groups (i.e., sulfonate groups) in the presence of sodium sulfite. The MCTH and MCTH-g-p(GMA)-SO3H beads were characterized by ATR-FTIR, SEM, and VSM. The sulphonate groups content of the modified MCTH-g-p(GMA)-4 beads was found to be 0.53mmolg(-1) of beads by the potentiometric titration method. The MCTH-g-p(GMA)-SO3H beads were first used as an ion-exchange support for adsorption of lysozyme from aqueous solution. The influence of different experimental parameters such as pH, contact time, and temperature on the adsorption process was evaluated. The maximum adsorption capacity was found to be 208.7mgg(-1) beads. Adsorption of lysozyme on the MCTH-g-p(GMA)-SO3H beads fitted to Langmuir isotherm model and followed the pseudo second-order kinetic. More than 93% of the adsorbed lysozyme was desorbed using Na2CO3 solution (pH 11.0). The purity of the lysozyme was checked by HPLC and SDS gel electrophoresis. In addition, the MCTH-g-p(GMA)-SO3H beads prepared in this work showed promising potential for separation of various anionic molecules. Copyright © 2015 Elsevier B.V. All rights reserved.

  16. Addition of Granulocyte/Monocyte Apheresis to Oral Prednisone for Steroid-dependent Ulcerative Colitis: A Randomized Multicentre Clinical Trial.

    Science.gov (United States)

    Domènech, Eugeni; Panés, Julián; Hinojosa, Joaquín; Annese, Vito; Magro, Fernando; Sturniolo, Giacomo Carlo; Bossa, Fabrizio; Fernández, Francisco; González-Conde, Benito; García-Sánchez, Valle; Dignass, Axel; Herrera, José Manuel; Cabriada, José Luis; Guardiola, Jordi; Vecchi, Maurizio; Portela, Francisco; Ginard, Daniel

    2018-05-25

    Steroid-dependency occurs in up to 30% of patients with ulcerative colitis [UC]. In this setting, few drugs have demonstrated efficacy in inducing steroid-free remission. The aim of this study was to evaluate the efficacy and safety of adding granulocyte/monocyte apheresis [GMA] to oral prednisone in patients with steroid-dependent UC. This was a randomized, multicentre, open trial comparing 7 weekly sessions of GMA plus oral prednisone [40 mg/day and tapering] with prednisone alone, in patients with active, steroid-dependent UC [Mayo score 4-10 and inability to withdraw corticosteroids in 3 months or relapse within the first 3 months after discontinuation]. Patients were stratified by concomitant use of thiopurines at inclusion. A 9-week tapering schedule of prednisone was pre-established in both study groups. The primary endpoint was steroid-free remission [defined as a total Mayo score ≤2, with no subscore >1] at Week 24, with no re-introduction of corticosteroids. In all 123 patients were included [63 GMA group, 62 prednisone alone]. In the intention-to-treat analysis, steroid-free remission at Week 24 was achieved in 13% (95% confidence interval [CI] 6-24) in the GMA group and 7% [95% CI 2-16] in the control group [p = 0.11]. In the GMA group, time to relapse was significantly longer (hazard ratio [HR] 1.7 [1.16-2.48], P = 0.005) and steroid-related adverse events were significantly lower [6% vs 20%, P < 0.05]. In a randomized trial, the addition of 7 weekly sessions of GMA to a conventional course of oral prednisone did not increase the proportion of steroid-free remissions in patients with active steroid-dependent UC, though it delayed clinical relapse.

  17. Towards Wearable Cognitive Assistance

    Science.gov (United States)

    2013-12-01

    MHz 2002 Itanium R© 1 GHz Blackberry 133 MHz 5810 2007 Intel R© 9.6 GHz Apple 412 MHz CoreTM 2 (4 cores) iPhone 2011 Intel R© 32 GHz Samsung 2.4 GHz...Xeon R© X5 (2x6 cores) Galaxy S2 (2 cores) 2013 Intel R© 64 GHz Samsung 6.4 GHz Xeon R© E5 (2x12 cores) Galaxy S4 (4 cores) Google Glass 2.4 GHz OMAP... diverse inputs: the language content and deep semantics of the words, the tone in which they are spoken, the facial expressions and eye movements with

  18. Smart contracts sobre Bitcoin

    OpenAIRE

    Andreu Alemany, Josep Miquel

    2016-01-01

    El present treball final de màster realitza una introducció als smart contracts. El treball introdueix el concepte de contracte intel·ligent, els seus usos i alguns exemples existents. Seguidament proporciona les nocions necessàries de les transaccions del protocol Bitcoin per poder implementar un contracte intel·ligent, usant la blockchain que ofereix el protocol. Per últim, s'explica la implementació d'un contracte intel·ligent usant bitcoin: un canal de micropagaments. El presente traba...

  19. Production of sorption-active polypropylene fibers by radiation-induced grafting of glycidyl methacrylate as a precursor monomer

    International Nuclear Information System (INIS)

    Bondar, Yu.V.; Kim, H.J.; Lim, Y.J.

    2006-01-01

    The design and development of sorption-active natural and synthetic polymer fibers and textile materials is of great scientific and practical interest. The advantages of that type of polymeric adsorbents, as their highly developed specific surface, excellent ion-exchange and adsorption parameters and ease of their use especially under continuous conditions, allow them to find a great application in the chemical, biomedical, ecological and industrial fields. To obtain functional polymer materials with the desired performance, the non-active polymer surface have to be modified. Among different innovative techniques used for the introduction of graft chains, the radiation-chemical method of initiation has some economical and ecological preferences over others. It allows to introduce into inert polymeric matrix chains of a monomer already containing a desirable functional group, or to graft chains of a precursor-monomer and subsequently its chemical modification to form required functional groups. At present an epoxy-group containing monomer, glycidyl methacrylate (GMA), is successfully used as a precursor-monomer for production of polymeric adsorbents of variety applications on the base of membranes, films, fibers and fabrics. Two types of sorption-active polypropylene fiber carrying strong-acid sulfonate groups and amino groups have been synthesized by radiation-induced graft polymerization of GMA, with subsequent chemical modification of the epoxy groups of poly-GMA graft chains. The effect of various polymerization parameters on the GMA grafting degree was investigated in detail. The epoxy ring-opening of poly-GMA graft chains with introduction of strong-acid sulfonate groups was carried out with sodium hydrogen sulfite in water-dimethylformamide solution at 70 deg C. The main peculiarities of the sulfonation reaction in depending on the reaction time and GMA grafting degree have been investigated. Amine groups were incorporated by treatment of the GMA

  20. A multidimensional continued fraction and some of its statistical properties

    International Nuclear Information System (INIS)

    Baldwin, P.R.

    1992-01-01

    The problem of simultaneously approximating a vector of irrational numbers with rationals is analyzed in a geometrical setting using notions of dynamical systems theory. The author discusses here a (vectorial) multidimensional continued-fraction algorithm (MCFA) of additive type, the generalized mediant algorithm (GMA), and gives a geometrical interpretation to it. He calculates the invariant measure of the GMA shift as well as its Kolmogorov-Sinai (KS) entropy for arbitrary number of irrationals. The KS entropy is related to the growth rate of denominators of the Euclidean algorithm. This is the first analytical calculation of the growth rate of denominators for any MCFA

  1. Study and Optimization on graft polymerization under normal pressure and air atmospheric conditions, and its application to metal adsorbent

    Science.gov (United States)

    Ueki, Yuji; Chandra Dafader, Nirmal; Hoshina, Hiroyuki; Seko, Noriaki; Tamada, Masao

    2012-07-01

    Radiation-induced graft polymerization of glycidyl methacrylate (GMA) onto non-woven polyethylene (NWPE) fabric was achieved under normal pressure and air atmospheric conditions, without using unique apparatus such as glass ampoules or vacuum lines. To attain graft polymerization under normal pressure and air atmospheric conditions, the effects of the pre-irradiation dose, pre-irradiation atmosphere, pre-irradiation temperature, de-aeration of GMA-emulsion, grafting atmosphere in a reactor, and dissolved oxygen (DO) concentration in GMA-emulsion on the degree of grafting (Dg) were investigated in detail. It was found that the DO concentration had the strongest influence, the pre-irradiation dose, de-aeration of emulsion and grafting atmosphere had a relatively strong impact, and the pre-irradiation atmosphere and pre-irradiation temperature had the least effect on Dg. The optimum DO concentration before grafting was 2.0 mg/L or less. When a polyethylene bottle was used as a reactor instead of a glass ampoule, graft polymerization under normal pressure and air atmospheric conditions could be achieved under the following conditions; the pre-irradiation dose was more than 50 kGy, the volume ratio of GMA-emulsion to air was 50:1 or less, and the DO concentration in GMA-emulsion during grafting was below 2.0 mg/L. Under these grafting conditions, Dg was controlled within a range of up to 362%. The prepared GMA-grafted NWPE (GMA-g-NWPE) fabric was modified with a phosphoric acid to obtain an adsorbent for heavy metal ions. In the column-mode adsorption tests of Pb(II), the adsorption performance of the produced phosphorylated GMA-g-NWPE fabric (fibrous metal adsorbent) was not essentially dependent on the flow rate of the feed. The breakthrough points of 200, 500, and 1000 h-1 in space velocity were 483, 477 and 462 bed volumes, and the breakthrough capacities of the three flow rates were 1.16, 1.15 and 1.16 mmol-Pb(II)/g-adsorbent.

  2. Composite resin as an implant material in bone. Histologic, radiologic, microradiologic and oxytetracycline fluorescence examination of rats

    Energy Technology Data Exchange (ETDEWEB)

    Vainio, J; Rokkanen, P [Tampere Univ. (Finland). Inst. of Clinical Sciences; Central Hospital, Tampere (Finland))

    1978-01-01

    The potential of a bis-GMA composite resin as implant material in bone is evaluated. The material is claimed to have mechanical and physical properties superior to those of the bone cements used today. A groove made in the cortex of the tibia in 18 rats was filled with bis-GMA, while a similar was left empty in the contralateral tibia. The reaction of the bone to this material was evaluated by histologic, radiologic, microradiograph and OTC-fluorescence methods. The material was well tolerated by the bone; after 1,3 and 6 weeks no reaction to the material was observed.

  3. New CO2 adsorbent containing aminated poly(glycidyl methacrylate) grafted onto irradiated PE-PP nonwoven sheet

    Science.gov (United States)

    Mahmoud Nasef, Mohamed; Abbasi, Ali; Ting, T. M.

    2014-10-01

    A new CO2 adsorbent containing triethylamine (TEA) was prepared by radiation induced grafting of glycidyl methacrylate (GMA) onto polyethylene coated polypropylene (PE-PP) non-woven sheet followed by amination reaction. The degree of grafting (DOG%) was controlled by variation of monomer concentration and absorbed dose. The incorporation of aminated poly(GMA) was investigated by Fourier transform infrared (FTIR) and scanning electron microscope (SEM). The adsorbent with DOG of 350% and amination yield of 60% exhibited CO2 adsorption capacity of 4.52 mol/kg at ambient temperature and pressure.

  4. The distribution of nanoclay particles at the interface and their influence on the microstructure development and rheological properties of reactively processed biodegradable polylactide/poly(butylene succinate) blend nanocomposites

    CSIR Research Space (South Africa)

    Salehiyan, Reza

    2017-08-01

    Full Text Available . Nonlinear coefficient from FT-rheology was found to be more pronounced in case of blends filled with C30B, indicating better dispersion of C30B compare with BET which was in agreement with the SAXS results. Keywords: reactively compatibilized clay... reduced significantly upon C30B addition. Kumar et al. [11] found that Cloisite®20A (C20A) can intercalate and exfoliate into the PLA/PBAT matrices when GMA was used; which indicates that GMA can facilitate the exfoliation of clay particles into the blend...

  5. Adherence to the Food and Agricultural Organization guidelines on trypanocide usage among cattle farmers in Itezhi tezhi, Central Zambia.

    Science.gov (United States)

    Mbewe, Njelembo J; Sitali, Lungowe; Namangala, Boniface; Michelo, Charles

    2015-04-15

    Trypanocides will continue to play an important role in the control of tsetse fly transmitted trypanosomosis now and in the near future. The drugs are mostly administered by farmers without any veterinary supervision leading to misuse and under dosing of medication, and these could be factors that promote trypanocidal drug resistance (TDR) development. In order to delay or prevent TDR, the Food and Agriculture Organization (FAO) recommended guidelines on trypanocide use. It is not known if these recommended guidelines are adhered to in Itezhi tezhi district of Zambia. A survey was undertaken to examine how socio-economic and environmental factors were associated with adherence to the recommended guidelines on trypanocide use in Itezhi tezhi, Central Zambia. Ninety farmers who use trypanocides were interviewed using a questionnaire to collect their socio-economic characteristics (age, education in years, cattle herd size, competence on trypanocide use and their access to extension on trypanocide use) and trypanocide usage practices while crush pens which they use were stratified according to location, whether in the Game Management Area (GMA) (Mutenda, Itumbi, Kapulwe and Banachoongo) or non-GMA (Iyanda, New Ngoma and Shinampamba) as an environmental factor. Associations and measures of associations to adherence of FAO guidelines were determined. The results showed that 25.6% of the farmers adhered to guidelines by FAO on trypanocide use and that none of the socio-economic factors under investigation were significantly associated with it. Further the farmers that used crush pens that were in the GMA had an 80% reduction in the likelihood of adhering to the FAO guidelines on trypanocide use than those that used crush pens in the non-GMA (AOR 0.20, 95% CI: 0.05-0.81, P=0.02). There was low adherence to the recommended FAO guidelines on trypanocide use and it was associated with the location of the crush pen whether in the GMA or not, as an environmental factor. With

  6. Growth of MCF-7 breast cancer cells and efficacy of anti-angiogenic agents in a hydroxyethyl chitosan/glycidyl methacrylate hydrogel.

    Science.gov (United States)

    Wang, Hejing; Qian, Junmin; Zhang, Yaping; Xu, Weijun; Xiao, Juxiang; Suo, Aili

    2017-01-01

    Breast cancer negatively affects women's health worldwide. The tumour microenvironment plays a critical role in tumour initiation, proliferation, and metastasis. Cancer cells are traditionally grown in two-dimensional (2D) cultures as monolayers on a flat solid surface lacking cell-cell and cell-matrix interactions. These experimental conditions deviate from the clinical situation. Improved experimental systems that can mimic the in vivo situation are required to discover new therapies, particularly for anti-angiogenic agents that mainly target intercellular factors and play an essential role in treating some cancers. Chitosan can be modified to construct three-dimensional (3D) tumour models. Here, we report an in vitro 3D tumour model using a hydroxyethyl chitosan/glycidyl methacrylate (HECS-GMA) hydrogel produced by a series of chitosan modifications. Parameters relating to cell morphology, viability, proliferation, and migration were analysed using breast cancer MCF-7 cells. In a xenograft model, secretion of angiogenesis-related growth factors and the anti-angiogenic efficacy of Endostar and Bevacizumab in cells grown in HECS-GMA hydrogels were assessed by immunohistochemistry. Hydroxyethyl chitosan/glycidyl methacrylate hydrogels had a highly porous microstructure, mechanical properties, swelling ratio, and morphology consistent with a 3D tumour model. Compared with a 2D monolayer culture, breast cancer MCF-7 cells residing in the HECS-GMA hydrogels grew as tumour-like clusters in a 3D formation. In a xenograft model, MCF-7 cells cultured in the HECS-GMA hydrogels had increased secretion of angiogenesis-related growth factors. Recombinant human endostatin (Endostar), but not Bevacizumab (Avastin), was an effective anti-angiogenic agent in HECS-GMA hydrogels. The HECS-GMA hydrogel provided a 3D tumour model that mimicked the in vivo cancer microenvironment and supported the growth of MCF7 cells better than traditional tissue culture plates. The HECS-GMA

  7. Narrow groove gas metal-arc welding of aluminum

    International Nuclear Information System (INIS)

    Armstrong, R.E.

    1975-01-01

    The Gas Metal-Arc (GMA) welding process is explained and the equipment used described with an analysis of power supply function and the action of the arc, followed by discussion of general applications and problems. GMA braze welding of beryllium is then described, as is the development of a special high purity filler wire and a narrow deep groove joint design for improved weld strength in beryllium. This joint design and the special wire are applied in making high strength welds in high strength aluminum for special applications. High speed motion pictures of the welding operation are shown to illustrate the talk. (auth)

  8. Toward a High Performance Tile Divide and Conquer Algorithm for the Dense Symmetric Eigenvalue Problem

    KAUST Repository

    Haidar, Azzam; Ltaief, Hatem; Dongarra, Jack

    2012-01-01

    dynamic runtime system to multicore architectures. A detailed analysis of performance and accuracy is included. Performance improvements of 14-fold and 4-fold speedups are reported relative to LAPACK and Intel's Math Kernel Library.

  9. Performance Evaluation of Hyper Threading Technology ...

    African Journals Online (AJOL)

    PROF. OLIVER OSUAGWA

    2015-12-01

    Dec 1, 2015 ... Architecture Using Microsoft Operating System Platform. 1 Okonta O.E., 2 Ajani ... this means operating systems and user programs can ..... access nature of the Intel® Core™ i7 processor based ..... Operating systems manage.

  10. Block Fusion on Dynamically Adaptive Spacetree Grids for Shallow Water Waves

    KAUST Repository

    Weinzierl, Tobias; Bader, Michael; Unterweger, Kristof; Wittmann, Roland

    2014-01-01

    granular blocks. We study the fusion with a state-of-the-art shallow water solver at hands of an Intel Sandy Bridge and a Xeon Phi processor where we anticipate their reaction to selected block optimisation and vectorisation.

  11. The development of the time-keeping clock with TS-1 single chip microcomputer.

    Science.gov (United States)

    Zhou, Jiguang; Li, Yongan

    The authors have developed a time-keeping clock with Intel 8751 single chip microcomputer that has been successfully used in time-keeping station. The hard-soft ware design and performance of the clock are introduced.

  12. High-Performance Computing Paradigm and Infrastructure

    CERN Document Server

    Yang, Laurence T

    2006-01-01

    With hyperthreading in Intel processors, hypertransport links in next generation AMD processors, multi-core silicon in today's high-end microprocessors from IBM and emerging grid computing, parallel and distributed computers have moved into the mainstream

  13. Testing the Tester: Lessons Learned During the Testing of a State-of-the-Art Commercial 14nm Processor Under Proton Irradiation

    Science.gov (United States)

    Szabo, Carl M., Jr.; Duncan, Adam R.; Label, Kenneth A.

    2017-01-01

    Testing of an Intel 14nm desktop processor was conducted under proton irradiation. We share lessons learned, demonstrating that complex devices beget further complex challenges requiring practical and theoretical investigative expertise to solve.

  14. Intelit kahtlustatakse konkurentsiseaduse rikkumises / Lauri Matsulevitsh

    Index Scriptorium Estoniae

    Matsulevitsh, Lauri

    2005-01-01

    Juunis esitas Inteli konkurent Advanced Micro Devices (AMD) USAs kohtule kaebuse, mille kohaselt on Intel ebakohaste meetoditega veennud arvutifirmasid mitte kasutama AMD toodangut. Inteli kontrolli all on 90% Windowsi tarkvaral töötavate personaalarvutite mikroprotsessorite turust

  15. Modern pulsed spectrometer EPR for longitudinal relaxation time (T1) investigation - computer programs for measurement and data analysis

    International Nuclear Information System (INIS)

    Ilnicki, J.; Koziol, J.; Galinski, W.; Oles, T.; Kostrzewa, J.; Froncisz, W.

    1994-01-01

    The computerized control and data processing systems for new spectrometer designed for nuclear magnetic resonance studies of biological samples are presented. Both programs were written for INTEL 386 processor and they works under the Windows 3.0 environment

  16. Flux in Tallinn

    Index Scriptorium Estoniae

    2004-01-01

    Rahvusvahelise elektroonilise kunsti sümpoosioni ISEA2004 klubiõhtu "Flux in Tallinn" klubis Bon Bon. Eestit esindasid Ropotator, Ars Intel Inc., Urmas Puhkan, Joel Tammik, Taavi Tulev (pseud. Wochtzchee). Klubiõhtu koordinaator Andres Lõo

  17. Peregrine System | High-Performance Computing | NREL

    Science.gov (United States)

    classes of nodes that users access: Login Nodes Peregrine has four login nodes, each of which has Intel E5 /scratch file systems, the /mss file system is mounted on all login nodes. Compute Nodes Peregrine has 2592

  18. 78 FR 9985 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing and Immediate Effectiveness of...

    Science.gov (United States)

    2013-02-12

    ... Symbol Cisco Systems, Inc CSCO Dell Inc DELL Facebook, Inc FB Intel Corporation INTC Microsoft... Reference Room, 100 F Street NE., Washington, DC 20549, on official business days between the hours of 10:00...

  19. Paranoiline ellujääja / Vello Rääk

    Index Scriptorium Estoniae

    Rääk, Vello

    2004-01-01

    Ungari emigrandist USA juhtimisguruks tõusnud Andras Grofi alias Andrew S. Grove'i elust ja karjäärist, juhtimispõhimõtteist ning olulisematest saavutustest maailma suurima mikroprotsessorite tootja Intel eesotsas. Vt. samas: Intelis tormilised ajad

  20. Tiigrihüppe Sihtasutus alustab koostööd firmaga / Signe Teder

    Index Scriptorium Estoniae

    Teder, Signe

    2001-01-01

    Tiigrihüppe Sihtasutus alustas koos Intel Corporationìga uut koolitusprogrammi koolitajatele. Kursuse sisu ja metoodika vastab haridusministeeriumi kinnitatud õpetajatele soovitatavatele IKT-alastele pädevustele ja "Tiigrihüpe Plus" arengukavale

  1. 75 FR 54682 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...

    Science.gov (United States)

    2010-09-08

    .... (``MOT''), Newmont Mining Corporation (``NEM''), NetFlix Inc. (``NFLX''), NVIDIA Corporation (``NVDA... (``QQQQ''), Bank of America Corporation (``BAC''), Citigroup, Inc. (``C''), Standard and Poor's Depositary..., Inc. (``AAPL''), General Electric Company (``GE''), JPMorgan Chase & Co. (``JPM''), Intel Corporation...

  2. Speaker Profiles and Abstracts

    Indian Academy of Sciences (India)

    and her students work in the area of condensed matter systems. She was ... These findings have helped to understand the assembly and dynamics ... His research areas include electronic design automation, formal methods and artificial intel-.

  3. Ballmer, Barrett weigh in on security

    CERN Multimedia

    Sullivan, T

    2003-01-01

    ORLANDO, Fla. - Speaking in separate sessions Tuesday at the Gartner Symposium/ITxpo, Microsoft CEO Steve Ballmer and Intel's chief Craig Barrett discussed the problems of computer/network security (1/2 page).

  4. Multi-core Microprocessors

    Indian Academy of Sciences (India)

    Based on empirical data, Gordon Moore .... there are numerous models of the same Intel microprocessor such as Pentium. 3). ... returns. The limit on instruction and thread-level processing coupled with ..... This style of parallel programming is.

  5. Inspiring Innovation

    CERN Multimedia

    CERN. Geneva

    2009-01-01

    Craig Barrett became Intel's fourth president in May 1997, chief executive officer in 1998 and chairman of the Board on May 18, 2005. Dr. Barrett also serves as Chairman of the United Nations Global Alliance for Information...

  6. OpenMP Parallelization and Optimization of Graph-based Machine Learning Algorithms

    Science.gov (United States)

    2016-05-01

    Understanding Application Data Movement Characteristics using Intel VTune Amplifier and Software Development Emulator tools, Intel Xeon Phi User Group...sured by a summation of the weights along the graph cut) for this problem. This is equivalent to assigning a scalar or vector value ui to each i th data...graph Laplacian [9]. By projecting all vectors onto this sub-eigenspace, the iteration step reduces to a simple coefficient update. 2.2 Semi-supervised

  7. I processorie Itanium "accelerano" il CERN

    CERN Multimedia

    2001-01-01

    "Il CERN è di nuovo in prima fila nell'abbinamento tra informatica e ricerca scientifica. L'organizzazione europea utilizzerà anche computer basati sui nuovi microprocessori Intel Itanium a 64 bit". - CERN is again at the forefront of the coupling of informatics and scientific research. The European organization will use computers with new 64 bit Intel Itanium microprocessors (0.5 page)

  8. Virtual Wingman: Harnessing the Future Unstructured Information Environment to Achieve Mission Success

    Science.gov (United States)

    2010-12-01

    Review reporter Erica Naone interviewed Amazon , Intel, Enomaly, and SUN Micro- systems executives concerning cloud computing use. They 17 suggested that...Naone interviewed Amazon , Intel, Enomaly, and SUN Micro- systems executives concerning cloud computing use. They Cloud Computing—By using a thin...Jesús Favela, Alfredo Preciado, and Aurora Vizcaino. “Agent-Based Ambient Intelligence for Healthcare.” AI Communications 18, no. 3 (September 2005

  9. NSW Executive Enhancements

    Science.gov (United States)

    1981-06-01

    attacked most effectively with networking. Indeed, it was the marked success of the Arpanet in providing programmers economical access to diverse... economically feasible in the present -5- -**nm- ,-- ^ NSW Final Report for the Period Ending December 1980 state of the art: it would have required...INTEL 8080 MFU. PLM80: a cross compiler for the INTEL 8080 MPU . MACR020: a cross assembler for the AN/UYK-20 computer. CMS2-M: a cross compiler

  10. Using Kokkos for Performant Cross-Platform Acceleration of Liquid Rocket Simulations

    Science.gov (United States)

    2017-05-08

    defined functors (like Thrust or Intel TBB) Backends for Nvidia GPU, Intel Xeon, Xeon Phi , IBM Power8, others. “View” data structure provides optimal... Architecture of my Kokkos framework Designed for minimally-invasive operation alongside large Fortran code. Everything is controlled from Fortran through a...Controls Kokkos initialization/finalization void initialize(…); void finalize(…); TVProperties* gettvproperties(); Architecture of my Kokkos framework

  11. Particle In Cell Codes on Highly Parallel Architectures

    Science.gov (United States)

    Tableman, Adam

    2014-10-01

    We describe strategies and examples of Particle-In-Cell Codes running on Nvidia GPU and Intel Phi architectures. This includes basic implementations in skeletons codes and full-scale development versions (encompassing 1D, 2D, and 3D codes) in Osiris. Both the similarities and differences between Intel's and Nvidia's hardware will be examined. Work supported by grants NSF ACI 1339893, DOE DE SC 000849, DOE DE SC 0008316, DOE DE NA 0001833, and DOE DE FC02 04ER 54780.

  12. Artillery Survivability Model

    Science.gov (United States)

    2016-06-01

    the simulation actually runs, but the graphic card does not render. Another feature of Unity is that the user can see profile data in Unity Editor...optimized the number of waypoints on a laptop with an integrated graphic card Intel HD4400. A dedicated graphic card would be better and faster. 47...manipulating x, y, and z values of the three-dimensional thread vector on a laptop that runs an Intel HD4400 on-board graphic card . In this function

  13. Perfmon2: a leap forward in performance monitoring

    International Nuclear Information System (INIS)

    Jarp, S; Jurga, R; Nowak, A

    2008-01-01

    This paper describes the software component, perfmon2, that is about to be added to the Linux kernel as the standard interface to the Performance Monitoring Unit (PMU) on common processors, including x86 (AMD and Intel), Sun SPARC, MIPS, IBM Power and Intel Itanium. It also describes a set of tools for doing performance monitoring in practice and details how the CERN openlab team has participated in the testing and development of these tools

  14. Perfmon2: a leap forward in performance monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Jarp, S; Jurga, R; Nowak, A [CERN, Geneva (Switzerland)], E-mail: Sverre.Jarp@cern.ch

    2008-07-15

    This paper describes the software component, perfmon2, that is about to be added to the Linux kernel as the standard interface to the Performance Monitoring Unit (PMU) on common processors, including x86 (AMD and Intel), Sun SPARC, MIPS, IBM Power and Intel Itanium. It also describes a set of tools for doing performance monitoring in practice and details how the CERN openlab team has participated in the testing and development of these tools.

  15. Perfmon2 a leap forward in performance monitoring

    CERN Document Server

    Jarp, S; Nowak, A

    2008-01-01

    This paper describes the software component, perfmon2, that is about to be added to the Linux kernel as the standard interface to the Performance Monitoring Unit (PMU) on common processors, including x86 (AMD and Intel), Sun SPARC, MIPS, IBM Power and Intel Itanium. It also describes a set of tools for doing performance monitoring in practice and details how the CERN openlab team has participated in the testing and development of these tools.

  16. Crosstalk: The Journal of Defense Software Engineering. Volume 22, Number 2, February 2009

    Science.gov (United States)

    2009-02-01

    possible system attacks. by Ron Greenfield and Dr. Charley Tichenor Enforcing Static Program Properties to Enable Safety-Critical Use of Java Software...Assurance by Ron Greenfield and Dr. Charley Tichenor, and Dr. Kelvin Nilsen’s Enforcing Static Program Properties in Safety-Critical Java Software Components...01&lang=en>. 5. Shakespeare, William. The Tempest. 6. Intel. “How Chips are Made.” 2008 <www.intel.com/ education /making chips/preparation.htm>. 7

  17. Perfmon2: a leap forward in performance monitoring

    Science.gov (United States)

    Jarp, S.; Jurga, R.; Nowak, A.

    2008-07-01

    This paper describes the software component, perfmon2, that is about to be added to the Linux kernel as the standard interface to the Performance Monitoring Unit (PMU) on common processors, including x86 (AMD and Intel), Sun SPARC, MIPS, IBM Power and Intel Itanium. It also describes a set of tools for doing performance monitoring in practice and details how the CERN openlab team has participated in the testing and development of these tools.

  18. Electronics Industry Study Report: Semiconductors and Defense Electronics

    Science.gov (United States)

    2003-01-01

    Access Memory (DRAM) chips and microprocessors. Samsung , Micron, Hynix, and Infineon control almost three-fourths of the DRAM market,8 while Intel alone...Country 2001 Sales ($B) 2002 Sales ($B) % Change % 2002 Mkt 1 1 Intel U.S. 23.7 24.0 1% 16.9% 2 3 Samsung Semiconductor S. Korea 6.3...located in four major regions: the United States, Europe, Japan, and the Asia-Pacific region (includes South Korea, China, Singapore, Malaysia , Taiwan

  19. Contracting in Complex Operations: Toward Developing a Contracting Framework for Security Sector Reconstruction and Reform

    Science.gov (United States)

    2014-01-01

    MoI 49 Table A–2. Tactical Level Participants. (41 Total) Intel NDS ANA ASOF ANCOP AUP ABP ALP Embedded Advisors and Trainers (15) Colonel USARNG...Province) 50 Table A–2. Tactical Level Participants (page 2 of 2) Intel NDS ANA ASOF ANCOP AUP ABP ALP Duty TitleOrganizationRank...advising deployments *** Served on both strategic and tactical levels ABP : Afghan Border Police ANCOP: Afghan Civil Order Police CAAT: COIN Advise and

  20. LTE-Enhanced Cognitive Radio Network Testbed (LTE-CORNET)

    Science.gov (United States)

    2016-11-01

    4 PERCENT_SUPPORTEDNAME FTE Equivalent: Total Number: Sub Contractors (DD882) Names of Personnel receiving masters degrees Names of personnel...Turbo, HT , 15M, 140W) Intel Core i7-3770 (3.4 GHz Quad Core, 77W) Dual Intel Xeon E5-2695 v4 (18C, 2.1GHz, 3.3GHz Turbo, 2400MHz, 45MB, 120W

  1. Wilson and Domainwall Kernels on Oakforest-PACS

    Science.gov (United States)

    Kanamori, Issaku; Matsufuru, Hideo

    2018-03-01

    We report the performance of Wilson and Domainwall Kernels on a new Intel Xeon Phi Knights Landing based machine named Oakforest-PACS, which is co-hosted by University of Tokyo and Tsukuba University and is currently fastest in Japan. This machine uses Intel Omni-Path for the internode network. We compare performance with several types of implementation including that makes use of the Grid library. The code is incorporated with the code set Bridge++.

  2. A minimum operating system based on the SM5300.01 magnetic tape recorder for the Micro-8 computer

    International Nuclear Information System (INIS)

    Kartashov, S.V.

    1987-01-01

    An operating system (OS) for microcomputers based on INTEL-8080, 8085 microprocessors oriented to use a magnetic tape recorder is described. This system comprises a tape-recorder manager and a file structure organization system (nucleus of OS), a symbol text editor, a macroassembler, an interactive disasembler and a program of communication with an EC-computer. The OS makes it possible to develop, debug, store and exploit the program written in INTEL-8085 assembly language

  3. Comparative Profiling of microRNA Expression in Soybean Seeds from Genetically Modified Plants and their Near-Isogenic Parental Lines

    Science.gov (United States)

    Wang, Yong; Lan, Qingkuo; Zhao, Xin; Xu, Wentao; Li, Feiwu; Wang, Qinying; Chen, Rui

    2016-01-01

    MicroRNAs (miRNAs) have been widely demonstrated to play fundamental roles in gene regulation in most eukaryotes. To date, there has been no study describing the miRNA composition in genetically modified organisms (GMOs). In this study, small RNAs from dry seeds of two GM soybean lines and their parental cultivars were investigated using deep sequencing technology and bioinformatic approaches. As a result, several differentially expressed gma-miRNAs were found between the GM and non-GM soybeans. Meanwhile, more differentially expressed gma-miRNAs were identified between distantly relatednon-GM soybeans, indicating that the miRNA components of soybean seeds varied among different soybean lines, including the GM and non-GM soybeans, and the extent of difference might be related to their genetic relationship. Additionally, fourteen novel gma-miRNA candidates were predicted in soybean seeds including a potential bidirectionally transcribed miRNA family with two genomic loci (gma-miR-N1). Our findings firstly provided useful data for miRNA composition in edible GM crops and also provided valuable information for soybean miRNA research. PMID:27214227

  4. Preparation and Performance of Amphiphilic Random Copolymer Noncovalently Modified MWCNTs/Epoxy Composite

    Directory of Open Access Journals (Sweden)

    MA Qiang

    2016-09-01

    Full Text Available An amphiphilic random copolymer of polyglycidyl methacrylate-co-N-vinyl carbazole P(GMA-co-NVC was synthesized by free radical polymerization and was used to noncovalently modify multi-walled carbon nanotubes (MWCNTs. The obtained P(GMA-co-NVC/MWCNTs was mixed with epoxy resin and used to reinforce epoxy resin. Polymer modified carbon nanotubes/epoxy resin composites were prepared by a casting molding method. Tensile test, electrical resistivity test and differential scanning calorimeter(DSC analysis were used to study the effect of polymer modified carbon nanotubes on the mechanical, electrical, and thermal properties of epoxy resin. The results show that the epoxy composite reinforced with P(GMA-co-NVC/MWCNTs shows a remarkable enhancement in both tensile strength and elongation at break compared to either the pure epoxy or the pristine MWCNTs/epoxy composites. In addition, the electrical conductivity of epoxy is significantly improved and the volume resistivity decreases from 1014Ω·m to 106Ω·m with 0.25% mass fraction loading of P(GMA-co-NVC/MWCNTs. Moreover, glass transition temperature of the epoxy composite also increases from 144℃ to 149℃.

  5. In vivo genotoxicity assessment of acrylamide and glycidyl methacrylate.

    Science.gov (United States)

    Dobrovolsky, Vasily N; Pacheco-Martinez, M Monserrat; McDaniel, L Patrice; Pearce, Mason G; Ding, Wei

    2016-01-01

    Acrylamide (ACR) and glycidyl methacrylate (GMA) are structurally related compounds used for making polymers with various properties. Both chemicals can be present in food either as a byproduct of processing or a constituent of packaging. We performed a comprehensive evaluation of ACR and GMA genotoxicity in Fisher 344 rats using repeated gavage administrations. Clastogenicity was measured by scoring micronucleated (MN) erythrocytes from peripheral blood, DNA damage in liver, bone marrow and kidneys was measured using the Comet assay, and gene mutation was measured using the red blood cell (RBC) and reticulocyte Pig-a assay. A limited histopathology evaluation was performed in order to determine levels of cytotoxicity. Doses of up to 20 mg/kg/day of ACR and up to 250 mg/kg/day of GMA were used. ACR treatment resulted in DNA damage in the liver, but not in the bone marrow. While ACR was not a clastogen, it was a weak (equivocal) mutagen in the cells of bone marrow. GMA caused DNA damage in the cells of bone marrow, liver and kidney, and induced MN reticulocytes and Pig-a mutant RBCs in a dose-dependent manner. Collectively, our data suggest that both compounds are in vivo genotoxins, but the genotoxicity of ACR is tissue specific. Published by Elsevier Ltd.

  6. Local Ecological Knowledge and Community- based Management ...

    African Journals Online (AJOL)

    knowledge has been used in the management of wildlife resources in the two areas. ... Union for Conservation of Nature (IUCN), the United Nations Environment ..... In general, it is believed that cutting down trees will disturb the pattern of rainfall. ... determine and monitor animal distribution in the Luangwa GMA and the ...

  7. pH-responsive diblock copolymers with two different fluorescent labels for simultaneous monitoring of micellar self-assembly and degree of protonation

    DEFF Research Database (Denmark)

    Madsen, Jeppe; Madden, George; Themistou, Efrosyni

    2018-01-01

    methacrylate [PyMA] is statistically copolymerized with glycerolmonomethacrylate (GMA) to introduce a suitable fluorescent label. The chain-ends of the PDPA block are labelled with cresylviolet perchlorate [CV] by exploiting the spin trap properties of this dye molecule. Below pH 6, fluorescence from both...

  8. Fusion Nodes: The Next Step in Combating the Global Terrorist Threat

    Science.gov (United States)

    2011-12-01

    Answer,” Organizational Dynamics, Winter 1979: 429. 151 Richard L. Daft , Organization Theory and Design, 9th Edition (Mason, OH: Thompson: South...Morning America, 9 June 2006. Accessed 29 September 2011, http://abcnews.go.com/GMA/Terrorism/story?id=2056386&page=1. Daft , Richard L

  9. Sense and sensibility: The role of cognitive and emotional intelligence in negotiation

    NARCIS (Netherlands)

    Schlegel, K.; Mehu, M.; Peer, J.M. van; Scherer, K.R.

    2018-01-01

    This study tested whether EI (conceptualized as a performance-based ability) predicted economic and relational outcomes in an employee-recruiter negotiation above general mental ability (GMA) and whether a novel measure of emotion recognition ability (ERA; a central component of EI) predicted these

  10. Synthesis of acrylic prepolymer

    International Nuclear Information System (INIS)

    Hussin bin Mohd Nor; Dahlan bin Haji Mohd; Mohamad Hilmi bin Mahmood.

    1988-04-01

    An acrylic prepolymer was synthesized from glycidyl methacrylate (GMA), butyl methacrylate (BMA), methyl methacrylate (MMA) and acrylic acid (AA). Butyl acetate (BAc), benzoyl peroxide (BzO), 4-methoxyphenol (MPh) and triethylamine (TEA) were used as solvent, initiator, inhibitor and catalyst respectively. Observations of the synthesis leading to the formation of acrylic prepolymer are described. (author)

  11. Southern images - RGP gmap | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available 01-003 Description of data contents Parents Southern hybridization image files. Data file File name: rgp_gma...p File size: 37.3 MB Simple search URL - Data acquisition method Southern hybridization... Data analysis method For genotype segregation in F2 plants, Southern hybridization was performed with

  12. Control of drug releasing from biodegradable polymer drug delivery system by gamma-ray irradiation

    International Nuclear Information System (INIS)

    Yoshioka, Sumie; Aso, Yukio; Kojima, Shigeo

    1999-01-01

    In order to introduce the drug to the target organ, we developed a gel to control the drug releasing velocity by response to change of temperature by means of γ-ray irradiation to gelatin-GMA modified dextran mixture aqueous solution. A certain level of molecular weight of drug is necessary. The response to the temperature (change of drug releasing velocity) was affected by the concentration of gelatin and the modification rate of GMA. The Higuchi equation was applied to the releasing of β-galactosidase from gelatin-dextran gel and the releasing velocity was calculated. The releasing velocity decreased with increasing GMA modification rate at 37degC and 15degC. The releasing velocity of β-galactosidase decreased with increasing the concentration of gelatin at 15degC, but the velocity increased with increasing the concentration at 37degC. These results indicated that the good drug releasing conditions are obtained by controlling the GMA modification rate and the concentration of gelatin. (S.Y.)

  13. Effect Sizes for Growth-Modeling Analysis for Controlled Clinical Trials in the Same Metric as for Classical Analysis

    Science.gov (United States)

    Feingold, Alan

    2009-01-01

    The use of growth-modeling analysis (GMA)--including hierarchical linear models, latent growth models, and general estimating equations--to evaluate interventions in psychology, psychiatry, and prevention science has grown rapidly over the last decade. However, an effect size associated with the difference between the trajectories of the…

  14. Comparison of implant cast accuracy of multiple implant impression technique with different splinting materials: An in vitro study

    Directory of Open Access Journals (Sweden)

    Sunantha Selvaraj

    2016-01-01

    Conclusion: The master cast obtained by both the splinting material exhibits no difference from the reference model. So bis-GMA can be used, which is easy to handle, less time consuming, less technique sensitive, rigid, and readily available material in clinics.

  15. Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on performance and metabolism of laying hens.

    Science.gov (United States)

    Chowdhury, S R; Smith, T K

    2004-11-01

    An experiment was conducted to evaluate the effects of feeding laying hens grains naturally contaminated with a combination of Fusarium mycotoxins. Parameters measured included performance, organ weights, and plasma chemistry. One hundred and forty-four, 45-wk-old laying hens were fed diets including: (1) control, (2) contaminated grains, and (3) contaminated grains + 0.2% polymeric glucomannan mycotoxin adsorbent (GMA) for a 12-wk period. The feeding of contaminated grains decreased feed consumption compared with controls in the first 4 wk. Feed consumption increased, however, from 4 to 8 wk and from 8 to 12 wk. The efficiency of feed utilization (feed consumption/egg mass) decreased compared with controls in the periods from 4 to 8 and from 8 to 12 wk when birds were fed contaminated grains. Supplementation with GMA decreased feed consumption and increased the efficiency of feed utilization in the period from 8 to 12 wk. Egg production and egg mass decreased in wk 4 and 8 compared with controls when contaminated grains were fed, whereas egg and eggshell weights decreased in the fourth wk. Plasma uric acid concentrations increased throughout the experiment and relative kidney weights increased at the end of the experiment compared with controls when birds were fed contaminated grains. The feeding of GMA prevented the elevation in uric acid concentrations and relative kidney weights. It was concluded that layer performance and metabolism were adversely affected by chronic feeding of a combination of Fusarium mycotoxins, and that GMA prevented many of these effects.

  16. Influence of solar and geomagnetic activity in Gymnodinium catenatum (Dinophyceae) cultures.

    Science.gov (United States)

    Vale, Paulo

    2017-01-01

    Laboratory cultures of the paralytic shellfish poisoning producing microalga Gymnodinium catenatum were subjected to a hypo-osmotic shock and changes in cell concentration were observed in two separate experiments of 8 and 24 hours duration, respectively. The increase in geomagnetic activity (GMA), radio and X-ray fluxes and solar X-ray flares were negatively correlated with cell numbers. Cell losses were observed in the short experiment, but not in the longest one. GMA action was related to the course of the experimental period, while electromagnetic radiation (EMR) was only significantly related when the previous hours before the experiments were considered. The differential action windows might be indicative of two differential disruptive mechanisms: EMR might act on DNA synthesis and mitosis phases of the cell cycle (taking place in the dark period) and GMA might be more disruptive at the end of mytosis or cytokinesis phases taking place in the light period. Formation of long chains (> 4 cells/chain) was reduced with salinity and with temperatures above 27ºC but increased with EMR and GMA, particularly when grown at the highest temperatures recorded during the study period (≥28ºC).

  17. CRCHD Integrated Networks

    Science.gov (United States)

    INB supports two network-based programs—the National Outreach Network (NON) and the Geographic Management of Cancer Health Disparities Program (GMaP)—as well as advising on women’s health and sexual and gender minority opportunities within and across the NCI.

  18. Influence of compatibilizer and/or montmorillonite addition on the mechanical properties and morphology of PP/recycled PET blends

    International Nuclear Information System (INIS)

    Silva, Murilo S.; Souza, Adriana M.C.

    2011-01-01

    In this work, the mechanical properties and morphology PP/recycled PET blends with addition of P(E-co-MA-co-GMA) copolymer and/or montmorillonite clay (MMT) was investigated. The blends were obtained by extrusion and their morphology was observed by scanning electron microscopy. The mechanical properties were evaluated by tensile and impact tests. Thin films of nanocomposites were characterized by x-ray diffraction (XRD). The addition of P (E-co-MA-co-GMA) or MMT clay separately promoted a decrease of the dispersed phase size. XRD analysis indicated that there was incorporation of polymer in clay galleries. The addition of clay in PP / PET blend resulted in an increase of apparent elastic modulus, impact resistance and HDT and a decrease of tensile strength and elongation at break. The addition of P (E-co-MA-co-GMA) resulted in an increased impact strength and reduction of other properties. There were no significant changes on mechanical properties when the clay and P (E-co-MA-co-GMA) are added simultaneously. (author)

  19. Mass Atrocity Prevention and Response Options (MAPRO): A Policy Planning Handbook

    Science.gov (United States)

    2012-03-01

    human and associated with animals , insects, or infectious diseases. They may also be portrayed as a mortal enemy, a drain on or traitors to the na- tion...the hu- manity of victims, the cruelty of perpetrators, and the apathy of bystanders. They can call attention to 100 GMA situations in ways that may

  20. Liquid Metal Oscillation and Arc Behaviour during Welding

    NARCIS (Netherlands)

    Yudodibroto, B.Y.B.

    2010-01-01

    The purpose of this research is to obtain insight into the oscillation behaviour of the liquid metal and the arc behaviour during GMA welding. Observations of the weld pool and the arc were undertaken by visual means using a high-speed video and by analysis of the voltage. To deal with the complex

  1. Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on small intestinal morphology of turkeys.

    Science.gov (United States)

    Girish, C K; Smith, T K

    2008-06-01

    An experiment was conducted to investigate the effects of feeding grains naturally contaminated with Fusarium mycotoxins on morphometric indices of duodenum, jejunum, and ileum in turkeys. The possible preventative effect of a polymeric glucomannan mycotoxin adsorbent (GMA) was also determined. Three hundred 1-d-old male turkey poults were fed wheat, corn, and soybean meal-based starter (0 to 3 wk), grower (4 to 6 wk), developer (7 to 9 wk), and finisher (10 to 12 wk) diets formulated with control grains, contaminated grains, and contaminated grains + 0.2% GMA. Morphometric indices were measured at the end of each growth phase and included villus height (VH), crypt depth, villus width, thicknesses of submucosa and muscularis, villus-to-crypt ratio, and apparent villus surface area (AVSA). At the end of the starter phase, feedborne mycotoxins significantly decreased the VH in the duodenum, and supplementation of the contaminated diet with GMA prevented this effect. The feeding of contaminated grains also reduced (P effects in jejunum and ileum. No effects of diets were seen on morphometric variables at the end of the developer and finisher phases. It was concluded that consumption of grains naturally contaminated with Fusarium mycotoxins results in adverse effects on intestinal morphology during early growth phases of turkeys, and GMA can prevent many of these effects.

  2. Effects of feedborne fusarium mycotoxins on brain regional neurochemistry of turkeys.

    Science.gov (United States)

    Girish, C K; MacDonald, E J; Scheinin, M; Smith, T K

    2008-07-01

    An experiment was conducted to investigate the effects of feeding grains naturally contaminated with Fusarium mycotoxins on brain regional neurochemistry of turkeys. The possible preventative effect of a poly-meric glucomannan mycotoxin adsorbent (GMA) was also determined. Forty-five 1-d-old male turkey poults were fed wheat-, corn-, and soybean meal-based diets up to wk 6, formulated with control grains, contaminated grains, or contaminated grains + 0.2% GMA. Deoxynivalenol was the major contaminant, and the concentrations were 2.2 and 3.3 mg/kg of feed during starter and grower phases, respectively. Concentrations of brain monoamine neurotransmitters and metabolites were measured in discrete regions of the brain including the pons, hypothalamus, and cortex by HPLC with electrochemical detection. Neurotransmitters and metabolites analyzed included norepinephrine, dopamine, 3,4-dihydroxyphenylacetic acid, serotonin (5-hydroxytryptamine, 5-HT), and 5-hydroxyindoleacetic acid (5-HIAA). The concentration of 5-HIAA and the 5-HIAA:5-HT-ratio were significantly decreased in pons after feeding contaminated grains. Dietary supplementation with GMA prevented these effects. In the pons, a significant positive correlation (r = 0.52, P effects on the concentrations of neurotransmitters and metabolites in hypothalamus and cortex. It was concluded that consumption of grains naturally contaminated with Fusarium mycotoxins adversely altered the pons serotonergic system of turkeys. Supplementation with GMA partially inhibited these effects.

  3. Comparative Profiling of microRNA Expression in Soybean Seeds from Genetically Modified Plants and their Near-Isogenic Parental Lines.

    Science.gov (United States)

    Wang, Yong; Lan, Qingkuo; Zhao, Xin; Xu, Wentao; Li, Feiwu; Wang, Qinying; Chen, Rui

    2016-01-01

    MicroRNAs (miRNAs) have been widely demonstrated to play fundamental roles in gene regulation in most eukaryotes. To date, there has been no study describing the miRNA composition in genetically modified organisms (GMOs). In this study, small RNAs from dry seeds of two GM soybean lines and their parental cultivars were investigated using deep sequencing technology and bioinformatic approaches. As a result, several differentially expressed gma-miRNAs were found between the GM and non-GM soybeans. Meanwhile, more differentially expressed gma-miRNAs were identified between distantly relatednon-GM soybeans, indicating that the miRNA components of soybean seeds varied among different soybean lines, including the GM and non-GM soybeans, and the extent of difference might be related to their genetic relationship. Additionally, fourteen novel gma-miRNA candidates were predicted in soybean seeds including a potential bidirectionally transcribed miRNA family with two genomic loci (gma-miR-N1). Our findings firstly provided useful data for miRNA composition in edible GM crops and also provided valuable information for soybean miRNA research.

  4. Predicting factors influencing crop raiding by elephants in the ...

    African Journals Online (AJOL)

    Nyirenda et al.

    By developing predictive models of binary logistic regression and employing questionnaire surveys, we .... Lupande Game Management Area (GMA), covering an area of 4 840 km2 constitutes the ...... Temporal trends in elephant ... the modern conservation paradigm: Can agricultural communities co- exist with elephant?

  5. Comparative Profiling of microRNA Expression in Soybean Seeds from Genetically Modified Plants and their Near-Isogenic Parental Lines.

    Directory of Open Access Journals (Sweden)

    Yong Wang

    Full Text Available MicroRNAs (miRNAs have been widely demonstrated to play fundamental roles in gene regulation in most eukaryotes. To date, there has been no study describing the miRNA composition in genetically modified organisms (GMOs. In this study, small RNAs from dry seeds of two GM soybean lines and their parental cultivars were investigated using deep sequencing technology and bioinformatic approaches. As a result, several differentially expressed gma-miRNAs were found between the GM and non-GM soybeans. Meanwhile, more differentially expressed gma-miRNAs were identified between distantly relatednon-GM soybeans, indicating that the miRNA components of soybean seeds varied among different soybean lines, including the GM and non-GM soybeans, and the extent of difference might be related to their genetic relationship. Additionally, fourteen novel gma-miRNA candidates were predicted in soybean seeds including a potential bidirectionally transcribed miRNA family with two genomic loci (gma-miR-N1. Our findings firstly provided useful data for miRNA composition in edible GM crops and also provided valuable information for soybean miRNA research.

  6. Synthesis, characterization and in vitro cytotoxicity analysis of a novel cellulose based drug carrier for the controlled delivery of 5-fluorouracil, an anticancer drug

    Science.gov (United States)

    Anirudhan, Thayyath S.; Nima, Jayachandran; Divya, Peethambaran L.

    2015-11-01

    The present investigation concerns the development and evaluation of a novel drug delivery system, aminated-glycidylmethacrylate grafted cellulose-grafted polymethacrylic acid-succinyl cyclodextrin (Cell-g-(GMA/en)-PMA-SCD) for the controlled release of 5-Fluorouracil, an anticancer drug. The prepared drug carrier was characterized by FT-IR, XRD and SEM techniques. Binding kinetics and isotherm studies of 5-FU onto Cell-g-(GMA/en)-PMA-SCD were found to follow pseudo-second-order and Langmuir model respectively. Maximum binding capacity of drug carrier was found to be 149.09 mg g-1 at 37 °C. Swelling studies, in vitro release kinetics, drug loading efficiency and encapsulation efficiency of Cell-g-(GMA/en)-PMA-SCD were studied. The release kinetics was analyzed using Ritger-Peppas equation at pH 7.4. Cytotoxicity analysis on MCF-7 (human breast carcinoma) cells indicated that the drug carrier shows sustained and controlled release of drug to the target site. Hence, it is evident from this investigation that Cell-g-(GMA/en)-PMA-SCD could be a promising carrier for 5-FU.

  7. Liquid‐to‐solid ratio control as an advanced process control solution for continuous twin‐screw wet granulation

    DEFF Research Database (Denmark)

    Nicolaï, Niels; Leersnyder, Fien De; Copot, Dana

    2018-01-01

    for the dynamic behavior of the granule liquid‐to‐solid ratio (w) at the end of the granulation unit of a commercial ConsiGmaTM‐25 production line. Near‐infrared spectroscopy was used to monitor the granule composition in‐line. The outcome for both the tracking and regulator problem using either conventional...

  8. Isolation of microbial DNA by newly designed magnetic particles

    Czech Academy of Sciences Publication Activity Database

    Rittich, B.; Španová, A.; Horák, Daniel; Beneš, Milan J.; Klesnilová, L.; Petrová, K.; Rybnikář, A.

    2006-01-01

    Roč. 52, č. 2 (2006), s. 143-148 ISSN 0927-7765 R&D Projects: GA ČR GA203/05/2256; GA MZe 1G57037 Institutional research plan: CEZ:AV0Z40500505 Keywords : magnetic particles * P(HEMA-co-GMA) * cobalt ferrite Subject RIV: CD - Macromolecular Chemistry Impact factor: 1.789, year: 2006

  9. Adhesion of resin composites to biomaterials in dentistry : an evaluation of surface conditioning methods

    NARCIS (Netherlands)

    Özcan, Mutlu

    2003-01-01

    Since previous investigations revealed that most clinical failures in adhesively luted ceramic restorations initiate from the cementation or internal surfaces, the study presented in Chapter II evaluated the effect of three different surface conditioning methods on the bond strength of a Bis-GMA

  10. When Intelligence is (Dys)Functional for Achieving Sales Performance

    NARCIS (Netherlands)

    W.J.M.I. Verbeke (Willem); F.D. Belschak (Frank); A.B. Bakker (Arnold); H.M.S. Dietz (Bart)

    2008-01-01

    textabstractUsing two different samples of salespeople, the authors investigate how a combination of general mental ability (GMA) and specific skills and capabilities (social competence and thinking styles) allows salespeople to reach their sales goals. The study finds evidence for an interaction

  11. Studies of properties of rubber wood with impregnation of polymer

    Indian Academy of Sciences (India)

    Impregnation of rubber wood has been carried out under different conditions by using styrene as grafting monomer and glycidyl methacrylate (GMA) as crosslinker. Properties such as dimensional stability, water absorption, hardness, tensile strength, flexural strength, etc of the impregnated wood have been checked and ...

  12. Effect of Temperature on Granulocyte and Monocyte Adsorption to Cellulose Acetate Beads.

    Science.gov (United States)

    Nishise, Shoichi; Takeda, Yuji; Abe, Yasuhiko; Sasaki, Yu; Nara, Hidetoshi; Asao, Hironobu; Ueno, Yoshiyuki

    2017-06-01

    Granulocyte and monocyte (GM) adsorptive apheresis (GMA) is an effective therapy for inflammatory disorders including inflammatory bowel disease (IBD). During GMA, the blood of a patient with IBD passes through a column to contact cellulose acetate (CA) beads at a temperature below body temperature, likely close to room temperature. Here we investigated the effect of temperature on GM adsorption to CA beads in vitro. We incubated peripheral blood with and without CA beads at 5°C, 25°C, 37°C, and 43°C and calculated the ratios of adsorbed GMs. The ratios of adsorbed GMs increased as the temperature was raised. Additionally, we measured complement activation fragment concentrations. C3a and C5a concentrations also increased as the temperature was raised, and C5a concentrations had a positive correlation with the ratios of adsorbed GMs. These results suggest that warming the column during GMA might increase GM adsorption to CA beads, thereby enhancing the clinical efficacy of GMA. © 2017 International Society for Apheresis, Japanese Society for Apheresis, and Japanese Society for Dialysis Therapy.

  13. Tailored Training in Vehicle Maintenance Courses

    Science.gov (United States)

    2014-07-01

    1998) and that the predictive power of GMA often swamps that of specific (i.e., more narrow) tests ( Thorndike , 1985). 15...Command. Thorndike , R. L. (1985). The central role of general ability in prediction. Multivariate Behavioral Research, 20, 241-254. VanLehn, K

  14. Purification of yeast alcohol dehydrogenase by using immobilized metal affinity cryogels

    Energy Technology Data Exchange (ETDEWEB)

    Akduman, Begüm [Chemistry Department, Adnan Menderes University, Aydın (Turkey); Uygun, Murat [Koçarlı Vocational and Training School, Adnan Menderes University, Aydın (Turkey); Uygun, Deniz Aktaş, E-mail: daktas@adu.edu.tr [Chemistry Department, Adnan Menderes University, Aydın (Turkey); Akgöl, Sinan [Biochemistry Department, Ege University, İzmir (Turkey); Denizli, Adil [Chemistry Department, Hacettepe University, Ankara (Turkey)

    2013-12-01

    In this study, poly(2-hydroxyethyl methacrylate–glycidylmethacrylate) [poly(HEMA–GMA)] cryogels were prepared by radical cryocopolymerization of HEMA with GMA as a functional comonomer and N,N′-methylene-bisacrylamide (MBAAm) as a crosslinker. Iminodiacetic acid (IDA) functional groups were attached via ring opening of the epoxy group on the poly(HEMA–GMA) cryogels and then Zn(II) ions were chelated with these structures. Characterization of cryogels was performed by FTIR, SEM, EDX and swelling studies. These cryogels have interconnected pores of 30–50 μm size. The equilibrium swelling degree of Zn(II) chelated poly(HEMA–GMA)-IDA cryogels was approximately 600%. Zn(II) chelated poly(HEMA–GMA)-IDA cryogels were used in the adsorption of alcohol dehydrogenase from aqueous solutions and adsorption was performed in continuous system. The effects of pH, alcohol dehydrogenase concentration, temperature, and flow rate on adsorption were investigated. The maximum amount of alcohol dehydrogenase adsorption was determined to be 9.94 mg/g cryogel at 1.0 mg/mL alcohol dehydrogenase concentration and in acetate buffer at pH 5.0 with a flow rate of 0.5 mL/min. Desorption of adsorbed alcohol dehydrogenase was carried out by using 1.0 M NaCI at pH 8.0 phosphate buffer and desorption yield was found to be 93.5%. Additionally, these cryogels were used for purification of alcohol dehydrogenase from yeast with a single-step. The purity of desorbed alcohol dehydrogenase was shown by silver-stained SDS–PAGE. This purification process can successfully be used for the purification of alcohol dehydrogenase from unclarified yeast homogenates and this work is the first report about the usage of the cryogels for purification of alcohol dehydrogenase. - Highlights: • Poly(HEMA–GMA) cryogels were synthesized by radical cryocopolymerization technique. • Prepared cryogels were functionalized with IDA, then Zn(II) ions were chelated to the cryogel. • Zn(II) chelated poly(HEMA–GMA

  15. Purification of yeast alcohol dehydrogenase by using immobilized metal affinity cryogels

    International Nuclear Information System (INIS)

    Akduman, Begüm; Uygun, Murat; Uygun, Deniz Aktaş; Akgöl, Sinan; Denizli, Adil

    2013-01-01

    In this study, poly(2-hydroxyethyl methacrylate–glycidylmethacrylate) [poly(HEMA–GMA)] cryogels were prepared by radical cryocopolymerization of HEMA with GMA as a functional comonomer and N,N′-methylene-bisacrylamide (MBAAm) as a crosslinker. Iminodiacetic acid (IDA) functional groups were attached via ring opening of the epoxy group on the poly(HEMA–GMA) cryogels and then Zn(II) ions were chelated with these structures. Characterization of cryogels was performed by FTIR, SEM, EDX and swelling studies. These cryogels have interconnected pores of 30–50 μm size. The equilibrium swelling degree of Zn(II) chelated poly(HEMA–GMA)-IDA cryogels was approximately 600%. Zn(II) chelated poly(HEMA–GMA)-IDA cryogels were used in the adsorption of alcohol dehydrogenase from aqueous solutions and adsorption was performed in continuous system. The effects of pH, alcohol dehydrogenase concentration, temperature, and flow rate on adsorption were investigated. The maximum amount of alcohol dehydrogenase adsorption was determined to be 9.94 mg/g cryogel at 1.0 mg/mL alcohol dehydrogenase concentration and in acetate buffer at pH 5.0 with a flow rate of 0.5 mL/min. Desorption of adsorbed alcohol dehydrogenase was carried out by using 1.0 M NaCI at pH 8.0 phosphate buffer and desorption yield was found to be 93.5%. Additionally, these cryogels were used for purification of alcohol dehydrogenase from yeast with a single-step. The purity of desorbed alcohol dehydrogenase was shown by silver-stained SDS–PAGE. This purification process can successfully be used for the purification of alcohol dehydrogenase from unclarified yeast homogenates and this work is the first report about the usage of the cryogels for purification of alcohol dehydrogenase. - Highlights: • Poly(HEMA–GMA) cryogels were synthesized by radical cryocopolymerization technique. • Prepared cryogels were functionalized with IDA, then Zn(II) ions were chelated to the cryogel. • Zn(II) chelated poly(HEMA–GMA

  16. Cage and linear structured polysiloxane/epoxy hybrids for coatings: Surface property and film permeability.

    Science.gov (United States)

    Ma, Yanli; He, Ling; Jia, Mengjun; Zhao, Lingru; Zuo, Yanyan; Hu, Pingan

    2017-08-15

    Three polysiloxane/epoxy hybrids obtained by evolving cage- or linear-structured polysiloxane into poly glycidyl methacrylate (PGMA) matrix are compared used as coatings. One is the cage-structured hybrid of P(GMA/MA-POSS) copolymer obtained by GMA and methacrylisobutyl polyhedral oligomeric silsesquioxane (MA-POSS) via free radical polymerization, the other two are PGMA/NH 2 -POSS and PGMA/NH 2 -PDMS hybrids by cage-structured aminopropyllsobutyl POSS (NH 2 -POSS) or linear-structured diamino terminated poly(dimethylsiloxane) (NH 2 -PDMS) to cure PGMA. The effect of MA-POSS, NH 2 -POSS and NH 2 -PDMS on polysiloxane/epoxy hybrid films is characterized according to their surface morphology, transparency, permeability, adhesive strength and thermo-mechanical properties. Due to caged POSS tending to agglomerate onto the film surface, P(GMA/MA-POSS) and PGMA/NH 2 -POSS films exhibit much more heterogeneous surfaces than PGMA/NH 2 -PDMS film, but the well-compatibility between epoxy matrix and MA-POSS has provided P(GMA/MA-POSS) film with much higher transmittance (98%) than PGMA/NH 2 -POSS film (24%), PGMA/NH 2 -PDMS film (27%) and traditional epoxy resin film (5%). The introduction of polysiloxane into epoxy matrix is confirmed to create hybrids with strong adhesive strength (526-1113N) and high thermos-stability (T g =262-282°C), especially the cage-structured P(GMA/MA-POSS) hybrid (1113N and 282°C), but the flexible PDMS improves PGMA/NH 2 -PDMS hybrid with much higher storage modulus (519MPa) than PGMA/NH 2 -POSS (271MPa), which suggests that PDMS is advantage in improving the film stiffness than POSS cages. However, cage-structured P(GMA/MA-POSS) and PGMA/NH 2 -POSS indicate higher permeability than PGMA/NH 2 -PDMS and traditional epoxy resin. Comparatively, the cage-structured P(GMA/MA-POSS) hybrid is the best coating in transparency, permeability, adhesive strength and thermostability, but linear-structured PGMA/NH 2 -PDMS hybrid behaviors the best coating in

  17. Variation in GMC Association Properties across the Bars, Spiral Arms, Inter-arms, and Circumnuclear Region of M100 (NGC 4321) Extracted from ALMA Observations

    Energy Technology Data Exchange (ETDEWEB)

    Pan, Hsi-An [Academia Sinica, Institute of Astronomy and Astrophysics (ASIAA), P.O. Box 23-141, Taipei 10617, Taiwan (China); Kuno, Nario, E-mail: hapan@asiaa.sinica.edu.tw [Faculty of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 350-8577 (Japan)

    2017-04-20

    We study the physical properties of giant molecular cloud associations (GMAs) in M100 (NGC 4321) using the ALMA Science Verification feathered (12 m+ACA) data in {sup 12}CO (1–0). To examine the environmental dependence of their properties, GMAs are classified based on their locations in various environments as circumnuclear ring (CNR), bar, spiral, and inter-arm GMAs. The CNR GMAs are massive and compact, while the inter-arm GMAs are diffuse, with low surface density. GMA mass and size are strongly correlated, as suggested by Larson. However, the diverse power-law index of the relation implies that the GMA properties are not uniform among the environments. The CNR and bar GMAs show higher velocity dispersion than those in other environments. We find little evidence for a correlation between GMA velocity dispersion and size, which indicates that the GMAs are in diverse dynamical states. Indeed, the virial parameter of the GMAs spans nearly two orders of magnitude. Only the spiral GMAs are generally self-gravitating. Star formation activity decreases in order over the CNR, spiral, bar, and inter-arm GMAs. The diverse GMA and star formation properties in different environments lead to variations in the Kennicutt–Schmidt relation. A combination of multiple mechanisms or gas phase change is necessary to explain the observed slopes. Comparisons of GMA properties acquired with the use of the 12 m array observations with those from the feathered data are also presented. The results show that the missing flux and extended emission cannot be neglected for the study of environmental dependence.

  18. Effect of carbon nanotube reinforcement on the properties of the recycled poly(ethylene terephthalate)/poly(ethylene naphthalate) (r-PET/PEN) blends containing functional elastomers

    International Nuclear Information System (INIS)

    Yesil, Sertan

    2013-01-01

    Highlights: • Mechanical properties of r-PET improved with addition of PEN, elastomers and CNT. • Elastomer size and dispersion played important role in the variation of properties. • Selective localization of CNT affected the mechanical and electrical properties. • E-EA-MAH based samples had higher mechanical properties than E-MA-GMA based ones. - Abstract: In this study, the mechanical, thermomechanical, thermal, electrical properties and the morphology of the composites, based on blends of recycled poly(ethylene terephthalate) (r-PET) and poly(ethylene naphthalate) (PEN) that were mixed with functional elastomers and multi walled carbon nanotube (CNT) were investigated. Two types of functional elastomers; terpolymer of ethylene–ethyl acrylate–maleic anhydride (E-EA-MAH) and terpolymer of ethylene–methyl acrylate–glycidyl methacrylate (E-MA-GMA), were used to ensure the miscibility between PET and PEN during the preparation of the blends and composites. All composite and blend samples were extruded by using a laboratory scale twin screw microcompounder. Test samples were prepared via laboratory scale injection molding machine. According to the results of the thermomechanical tests, usage of both elastomers enhanced the miscibility between r-PET and PEN. Morphological analyses showed that the blends and composites which contain E-EA-MAH exhibited better elastomer phase dispersion with smaller domain sizes when compared with the samples with E-MA-GMA. Samples prepared with E-EA-MAH had better mechanical properties than the ones containing E-MA-GMA due to the better elastomer phase dispersion. Moreover, addition of CNT also improved the mechanical properties of the samples for both elastomer types. In contrast to mechanical test results, samples prepared with E-MA-GMA had higher electrical conductivity values when compared with those of the ones containing E-EA-MAH due to the differences in the selective distribution of CNT particles between the

  19. Controlled protein adsorption on PMOXA/PAA based coatings by thermally induced immobilization

    Science.gov (United States)

    Mumtaz, Fatima; Chen, Chaoshi; Zhu, Haikun; Pan, Chao; Wang, Yanmei

    2018-05-01

    In this work, poly(2-methyl-2-oxazoline-random-glycidyl methacrylate) (PMOXA-r-GMA) and poly(acrylic acid)-block-poly(glycidyl methacrylate) (PAA-b-PGMA) copolymers were synthesized via cationic ring-opening polymerization (CROP) of 2-methyl-2-oxazoline (MOXA) and reversible addition-fragmentation chain transfer (RAFT) polymerization of acrylic acid (AA) followed by their random and block copolymerization with glycidyl methacrylate (GMA), respectively, and then characterized carefully. PMOXA/PAA based coatings were then prepared by simply spin coating the mixture of PMOXA-r-GMA and PAA-b-PGMA copolymer solutions onto silicon/glass substrates followed by annealing at 110 °C. The coatings were rigorously characterized by using X-ray photoelectron spectroscopy (XPS), the static water contact angle (WCA) test, ellipsometry and atomic force microscopy (AFM). The results demonstrated that the coating based mixed PMOXA/PAA brushes with desired surface composition could be attained by simply maintaining their percentage in the mixture of PMOXA-r-GMA and PAA-b-PGMA copolymer solutions. Finally, the switchable behavior of PMOXA/PAA based coatings toward bovine serum albumin (BSA) adsorption was investigated by fluorescein isothiocyanate-labelled BSA (FITC-BSA) assay and quartz crystal microbalance with dissipation monitoring (QCM-D), which indicated that the coating based mixed PMOXA/PAA brushes could control BSA adsorption/desorption from very low to high amount (>90% desorption) through adjusting the composition of PMOXA-r-GMA and PAA-b-PGMA solution used in preparing PMOXA/PAA based coatings upon pH and ionic strength change. Furthermore, PMOXA/PAA based coatings displayed efficient repeatability of reversible BSA adsorption/desorption cycles.

  20. Long-term follow-up with Granulocyte and Monocyte Apheresis re-treatment in patients with chronically active inflammatory bowel disease

    Directory of Open Access Journals (Sweden)

    Karlsson Mats

    2010-07-01

    Full Text Available Abstract Background Patients with IBD and chronic inflammation refractory to conventional therapy often demonstrate higher risk of serious complications. Combinations of immunosuppression and biological treatment as well as surgical intervention are often used in this patient group. Hence, there is need for additional treatment options. In this observational study, focused on re-treatment and long-term results, Granulocyte/Monocyte Adsorption (GMA, Adacolumn® treatment has been investigated to study efficacy, safety and quality of life in IBD-patients with chronic activity. Methods Fifteen patients with ulcerative colitis and 25 patients with Crohn's disease, both groups with chronically active inflammation refractory to conventional medication were included in this observational study. The patients received 5-10 GMA sessions, and the clinical activity was assessed at baseline, after each completed course, and at week 10 and 20 by disease activity index, endoscopy and quality of life evaluation. Relapsed patients were re-treated by GMA in this follow-up study up to 58 months. Results Clinical response was seen in 85% and complete remission in 65% of the patients. Ten patients in the UC-group (66% and 16 patients in the CD-group (64% maintained clinical and endoscopic remission for an average of 14 months. Fourteen patients who relapsed after showing initial remission were re-treated with GMA and 13 (93% went into a second remission. Following further relapses, all of seven patients were successfully re-treated for the third time, all of three patients for the fourth time and one for a fifth time. Conclusions IBD-patients with chronic inflammation despite conventional therapy seem to benefit from GMA. Re-treatment of relapsing remission patients seems to be effective.

  1. Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on performance, hematology, metabolism, and immunocompetence of turkeys.

    Science.gov (United States)

    Girish, C K; Smith, T K; Boermans, H J; Karrow, N A

    2008-03-01

    An experiment was conducted to investigate the effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on performance, hematology, metabolism, and immunological parameters of turkeys. The efficacy of polymeric glucomannan mycotoxin adsorbent (GMA) in preventing these adverse effects was also evaluated. Three hundred 1-d-old male turkey poults were fed wheat-, corn-, and soybean meal-based starter (0 to 3 wk), grower (4 to 6 wk), developer (7 to 9 wk), and finisher (10 to 12 wk) diets formulated with uncontaminated grains, contaminated grains, and contaminated grains + 0.2% GMA. Feeding contaminated grains significantly decreased BW gains during the grower and developer phases, and GMA supplementation prevented these effects. There was no effect of diet, however, on feed intake or feed efficiency. The feeding of contaminated grains reduced total lymphocyte counts at wk 3 (P effect. Feeding contaminated grains significantly increased the percentage of CD4(+) lymphocyte populations during wk 6; however, there was no change in the percentage of CD8(+) and B-lymphocyte populations. Contact hypersensitivity to dinitrochlorobenzene, which is a CD8(+) T cell-mediated delayed-type hypersensitivity response, was significantly decreased after 24 and 72 h by feedborne mycotoxins compared with controls. Supplementation of the contaminated diet with GMA prevented the decrease in response after 24 h. Secondary antibody (IgG titer) response against SRBC antigens (CD4(+) T cell-dependent) was significantly decreased after feeding contaminated grains compared with controls. It was concluded that turkey performance and some blood and immunological parameters were adversely affected by feedborne Fusarium mycotoxins, and GMA prevented many of these effects.

  2. [Application of electrogastrography in pediatrics. Part II. The incidence of disturbed gastric myoelectrical activity in children suffering from recurrent abdominal pain].

    Science.gov (United States)

    Maliszewska, Iwona; Krusiec-Swidergoł, Beata; Kasicka-Jonderko, Anna; Jonderko, Krzysztof; Błońska-Fajfrowska, Barbara

    2007-01-01

    The study was devoted to determine the incidence of an abnormal gastric myoelectrical activity (GMA) in children suffering from recurrent abdominal pain. Surface electrogastrograms were taken in the interdigestive state and after a meal stimulation in 187 children referred to the laboratory with the diagnosis of recurrent abdominal pain. The cohort comprised the following subgroups: age 6-11 years (33 boys and 36 girls), age 12-18 years (28 boys and 90 girls). Continuous variables characterizing quantitatively an electrogastrogram were recoded into categorical data sets, which were used further for construction of an arbitrary scale reflecting disturbances of an electrogastrographic recording: score 0--normal, score 1-2, 3-4, and 5-6 corresponding to a light, moderate, and severe disturbance of the GMA. Abnormal electrogastrograms were found in just over a half of the examined children (54.5%). Nevertheless, light abnormalities (score 1-2) were predominant--42.8% of the whole cohort. Moderate abnormalities were revealed in almost every eight patient (11.8%), whereas no case of severely disturbed GMA was disclosed. On the other hand as much as 45.5% children did not exhibit any abnormality of the electrogastrogram. No statistically significant differences were found when the frequency distributions of particular degrees of the GMA disturbance were compared among groups of different age and gender. A disclosure that an abnormal electrogastrogram is encountered in just over a half of the patients and the predominance of light disturbances within this group, implies that disturbed GMA is neither an inherent nor a pathognomonic pathological finding of the clinical picture of recurrent abdominal pain in children.

  3. Steady-state global optimization of metabolic non-linear dynamic models through recasting into power-law canonical models.

    Science.gov (United States)

    Pozo, Carlos; Marín-Sanguino, Alberto; Alves, Rui; Guillén-Gosálbez, Gonzalo; Jiménez, Laureano; Sorribas, Albert

    2011-08-25

    Design of newly engineered microbial strains for biotechnological purposes would greatly benefit from the development of realistic mathematical models for the processes to be optimized. Such models can then be analyzed and, with the development and application of appropriate optimization techniques, one could identify the modifications that need to be made to the organism in order to achieve the desired biotechnological goal. As appropriate models to perform such an analysis are necessarily non-linear and typically non-convex, finding their global optimum is a challenging task. Canonical modeling techniques, such as Generalized Mass Action (GMA) models based on the power-law formalism, offer a possible solution to this problem because they have a mathematical structure that enables the development of specific algorithms for global optimization. Based on the GMA canonical representation, we have developed in previous works a highly efficient optimization algorithm and a set of related strategies for understanding the evolution of adaptive responses in cellular metabolism. Here, we explore the possibility of recasting kinetic non-linear models into an equivalent GMA model, so that global optimization on the recast GMA model can be performed. With this technique, optimization is greatly facilitated and the results are transposable to the original non-linear problem. This procedure is straightforward for a particular class of non-linear models known as Saturable and Cooperative (SC) models that extend the power-law formalism to deal with saturation and cooperativity. Our results show that recasting non-linear kinetic models into GMA models is indeed an appropriate strategy that helps overcoming some of the numerical difficulties that arise during the global optimization task.

  4. Steady-state global optimization of metabolic non-linear dynamic models through recasting into power-law canonical models

    Directory of Open Access Journals (Sweden)

    Sorribas Albert

    2011-08-01

    Full Text Available Abstract Background Design of newly engineered microbial strains for biotechnological purposes would greatly benefit from the development of realistic mathematical models for the processes to be optimized. Such models can then be analyzed and, with the development and application of appropriate optimization techniques, one could identify the modifications that need to be made to the organism in order to achieve the desired biotechnological goal. As appropriate models to perform such an analysis are necessarily non-linear and typically non-convex, finding their global optimum is a challenging task. Canonical modeling techniques, such as Generalized Mass Action (GMA models based on the power-law formalism, offer a possible solution to this problem because they have a mathematical structure that enables the development of specific algorithms for global optimization. Results Based on the GMA canonical representation, we have developed in previous works a highly efficient optimization algorithm and a set of related strategies for understanding the evolution of adaptive responses in cellular metabolism. Here, we explore the possibility of recasting kinetic non-linear models into an equivalent GMA model, so that global optimization on the recast GMA model can be performed. With this technique, optimization is greatly facilitated and the results are transposable to the original non-linear problem. This procedure is straightforward for a particular class of non-linear models known as Saturable and Cooperative (SC models that extend the power-law formalism to deal with saturation and cooperativity. Conclusions Our results show that recasting non-linear kinetic models into GMA models is indeed an appropriate strategy that helps overcoming some of the numerical difficulties that arise during the global optimization task.

  5. Contact allergy to epoxy (meth)acrylates.

    Science.gov (United States)

    Aalto-Korte, Kristiina; Jungewelter, Soile; Henriks-Eckerman, Maj-Len; Kuuliala, Outi; Jolanki, Riitta

    2009-07-01

    Contact allergy to epoxy (meth)acrylates, 2,2-bis[4-(2-hydroxy-3-methacryloxypropoxy) phenyl]propane (bis-GMA), 2,2-bis[4-(2-hydroxy-3-acryloxypropoxy)phenyl]-propane (bis-GA), 2,2-bis[4-(methacryl-oxyethoxy)phenyl] propane (bis-EMA), 2,2-bis[4-(methacryloxy)phenyl]-propane (bis-MA), and glycidyl methacrylate (GMA) is often manifested together with contact allergy to diglycidyl ether of bisphenol A (DGEBA) epoxy resin. To analyse patterns of concomitant allergic reactions to the five epoxy (meth)acrylates in relation to exposure. We reviewed the 1994-2008 patch test files at the Finnish Institute of Occupational Health (FIOH) for reactions to the five epoxy (meth)acrylates, and examined the patients' medical records for exposure. Twenty-four patients had an allergic reaction to at least one of the studied epoxy (meth)acrylates, but specific exposure was found only in five patients: two bis-GMA allergies from dental products, two bis-GA allergies from UV-curable printing inks, and one bis-GA allergy from an anaerobic glue. Only 25% of the patients were negative to DGEBA epoxy resin. The great majority of allergic patch test reactions to bis-GMA, bis-GA, GMA and bis-EMA were not associated with specific exposure, and cross-allergy to DGEBA epoxy resin remained a probable explanation. However, independent reactions to bis-GA indicated specific exposure. Anaerobic sealants may induce sensitization not only to aliphatic (meth)acrylates but also to aromatic bis-GA.

  6. Morphological and mechanical properties of polyamide 6/linear low density polyethylene blend compatibilized by electron-beam initiated mediation process

    International Nuclear Information System (INIS)

    Shin, Boo Young; Han, Do Hung

    2014-01-01

    The aim of this study was to compatibilize immiscible polyamide 6 (PA6)/linear low density polyethylene (LLDPE) blend by using electron-beam initiated mediation process. Glycidyl methacrylate (GMA) was chosen as a mediator for cross-copolymerization at the interface between PA6 and LLDPE. The exposure process was carried out to initiate cross-copolymerization by the medium of GMA at the interface between PA and LLDPE. The mixture of the PA6/LLDPE/GMA was prepared by using a twin-screw extruder, and then the mixture was exposed to electron-beam radiation at various doses at room temperature. To investigate the results of this compatibilization strategy, the morphological and mechanical properties of the blend were analyzed. Morphology study revealed that the diameters of the dispersion particles decreased and the interfacial adhesion increased with respect to irradiation doses. The elongation at break of the blends increases significantly with increasing irradiation dose up to 100 kGy while the tensile strength and the modulus increased nonlinearly with increasing irradiation dose. The reaction mechanisms of the mediation process with the GMA mediator at the interface between PA6 and LLDPE were estimated. - Highlights: • PA6/LLDPE blend was compatibilized by the electron-beam initiated mediation process. • Interfacial adhesion was significantly enhanced by the radiation initiated cross-copolymerization. • The elongation at break of blend irradiated at 100 kGy was 4 times higher than PA6. • The GMA as a mediator played a key role in the electron-beam initiated mediation process

  7. Optimization of biotechnological systems through geometric programming

    Directory of Open Access Journals (Sweden)

    Torres Nestor V

    2007-09-01

    Full Text Available Abstract Background In the past, tasks of model based yield optimization in metabolic engineering were either approached with stoichiometric models or with structured nonlinear models such as S-systems or linear-logarithmic representations. These models stand out among most others, because they allow the optimization task to be converted into a linear program, for which efficient solution methods are widely available. For pathway models not in one of these formats, an Indirect Optimization Method (IOM was developed where the original model is sequentially represented as an S-system model, optimized in this format with linear programming methods, reinterpreted in the initial model form, and further optimized as necessary. Results A new method is proposed for this task. We show here that the model format of a Generalized Mass Action (GMA system may be optimized very efficiently with techniques of geometric programming. We briefly review the basics of GMA systems and of geometric programming, demonstrate how the latter may be applied to the former, and illustrate the combined method with a didactic problem and two examples based on models of real systems. The first is a relatively small yet representative model of the anaerobic fermentation pathway in S. cerevisiae, while the second describes the dynamics of the tryptophan operon in E. coli. Both models have previously been used for benchmarking purposes, thus facilitating comparisons with the proposed new method. In these comparisons, the geometric programming method was found to be equal or better than the earlier methods in terms of successful identification of optima and efficiency. Conclusion GMA systems are of importance, because they contain stoichiometric, mass action and S-systems as special cases, along with many other models. Furthermore, it was previously shown that algebraic equivalence transformations of variables are sufficient to convert virtually any types of dynamical models into

  8. Blood troponin levels in acute cardiac events depends on space weather activity components (a correlative study).

    Science.gov (United States)

    Stoupel, Eliiyahu; Radishauskas, Richardas; Bernotiene, Gailute; Tamoshiunas, Abdonas; Virvichiute, Daiva

    2018-02-05

    Many biological processes are influenced by space weather activity components such as solar activity (SA), geomagnetic activity (GMA) and cosmic ray activity (CRA). Examples are total mortality, acute myocardial infarction (AMI), stroke (cerebrovascular accident), sudden cardiac death, some congenital maladies (congenital heart disease and Down syndrome), many events in neonatology, ophtalmology, blood pressure regulation, blood coagulation, inflammation, etc. The aim of this study was to check if the level of blood troponins (Tns) - markers of myocardial damage and recognized components of modern description of AMI - is connected with the mentioned space weather parameters. Patients admitted to a 3000-bed tertiary university hospital in Kaunas, Lithuania, with suspected AMI were the object of the study. Data for the time between 2008 and 2013 - 72 consecutive months - were studied. Of the patients, 1896 (1398 male, 498 female) had elevated troponin I (Tn I) or troponin T (Tn T, sensitive Tn) levels. Normal values were 0.00-0.03 ng/mL for Tn I and 0.00-14.00 ng/mL for Tn T. Monthly means and standard deviation of Tn I and Tn T were compared with monthly markers of SA, GMA and CRA. Pearson correlation coefficients and their probabilities were established (in addition to the consecutive graphs of both comparing physical and biological data). The cosmophysical data came from space service institutions in the United States, Russia and Finland. AMI was diagnosed in 1188 patients (62.66%), and intermediate coronary syndrome in 698 patients (36.81%). There were significant links of the Tn blood levels with four SA indices and CRA (neutron activity in imp/min); there was no significant correlation with GMA indices Ap and Cp (p=0.27 and p=0.235). Tn T levels significantly correlated with the GMA indices and not with the SA and CRA levels (Ap: r=0.77, p=0.0021; Cp: r=0.729, p=0.0047). First, the monthly level of blood Tn I in ACS is significantly correlated with the indices

  9. Response of the mouse lung transcriptome to welding fume: effects of stainless and mild steel fumes on lung gene expression in A/J and C57BL/6J mice

    Directory of Open Access Journals (Sweden)

    Antonini James M

    2010-06-01

    Full Text Available Abstract Background Debate exists as to whether welding fume is carcinogenic, but epidemiological evidence suggests that welders are an at risk population for the development of lung cancer. Recently, we found that exposure to welding fume caused an acutely greater and prolonged lung inflammatory response in lung tumor susceptible A/J versus resistant C57BL/6J (B6 mice and a trend for increased tumor incidence after stainless steel (SS fume exposure. Here, our objective was to examine potential strain-dependent differences in the regulation and resolution of the lung inflammatory response induced by carcinogenic (Cr and Ni abundant or non-carcinogenic (iron abundant metal-containing welding fumes at the transcriptome level. Methods Mice were exposed four times by pharyngeal aspiration to 5 mg/kg iron abundant gas metal arc-mild steel (GMA-MS, Cr and Ni abundant GMA-SS fume or vehicle and were euthanized 4 and 16 weeks after the last exposure. Whole lung microarray using Illumina Mouse Ref-8 expression beadchips was done. Results Overall, we found that tumor susceptibility was associated with a more marked transcriptional response to both GMA-MS and -SS welding fumes. Also, Ingenuity Pathway Analysis revealed that gene regulation and expression in the top molecular networks differed between the strains at both time points post-exposure. Interestingly, a common finding between the strains was that GMA-MS fume exposure altered behavioral gene networks. In contrast, GMA-SS fume exposure chronically upregulated chemotactic and immunomodulatory genes such as CCL3, CCL4, CXCL2, and MMP12 in the A/J strain. In the GMA-SS-exposed B6 mouse, genes that initially downregulated cellular movement, hematological system development/function and immune response were involved at both time points post-exposure. However, at 16 weeks, a transcriptional switch to an upregulation for neutrophil chemotactic genes was found and included genes such as S100A8, S100A9 and

  10. Cell death effects of resin-based dental material compounds and mercurials in human gingival fibroblasts

    Energy Technology Data Exchange (ETDEWEB)

    Reichl, Franz-Xaver [Walther-Straub-Institute of Pharmacology and Toxicology, Munich (Germany); Ludwig-Maximilians-University, Department of Operative Dentistry and Periodontology, Munich (Germany); Esters, Magali; Simon, Sabine; Seiss, Mario [Walther-Straub-Institute of Pharmacology and Toxicology, Munich (Germany); Kehe, Kai [Bundeswehr Institute of Pharmacology and Toxicology, Munich (Germany); Kleinsasser, Norbert [University of Regensburg, Head and Neck Surgery, Department of Otolaryngology, Regensburg (Germany); Folwaczny, Matthias; Glas, Juergen; Hickel, Reinhard [Ludwig-Maximilians-University, Department of Operative Dentistry and Periodontology, Munich (Germany)

    2006-06-15

    In order to test the hypothesis that released dental restorative materials can reach toxic levels in human oral tissues, the cytotoxicities of the resin-based dental (co)monomers hydroxyethylmethacrylate (HEMA), triethyleneglycoldimethacrylate (TEGDMA), urethanedimethacrylate (UDMA), and bisglycidylmethacrylate (BisGMA) compared with methyl mercury chloride (MeHgCl) and the amalgam component mercuric chloride (HgCl{sub 2}) were investigated on human gingival fibroblasts (HGF) using two different test systems: (1) the modified XTT-test and (2) the modified H 33342 staining assay. The HGF were exposed to various concentrations of the test-substances in all test systems for 24 h. All tested (co)monomers and mercury compounds significantly (P<0.05) decreased the formazan formation in the XTT-test. EC{sub 50} values in the XTT assay were obtained as half-maximum-effect concentrations from fitted curves. Following EC{sub 50} values were found (mean [mmol/l]; s.e.m. in parentheses; n=12; * significantly different to HEMA): HEMA 11.530 (0.600); TEGDMA* 3.460 (0.200); UDMA* 0.106 (0.005); BisGMA* 0.087 (0.001); HgCl{sub 2}* 0.013 (0.001); MeHgCl* 0.005 (0.001). Following relative toxicities were found: HEMA 1; TEGDMA 3; UDMA 109; BisGMA 133; HgCl{sub 2} 887; MeHgCl 2306. A significant (P<0.05) increase of the toxicity of (co)monomers and mercurials was found in the XTT-test in the following order: HEMA < TEGDMA < UDMA < BisGMA < HgCl{sub 2} < MeHgCl. TEGDMA and MeHgCl induced mainly apoptotic cell death. HEMA, UDMA, BisGMA, and HgCl{sub 2} induced mainly necrotic cell death. The results of this study indicate that resin composite components have a lower toxicity than mercury from amalgam in HGF. HEMA, BisGMA, UDMA, and HgCl{sub 2} induced mainly necrosis, but it is rather unlikely that eluted substances (solely) can reach concentrations, which might induce necrotic cell death in the human physiological situation, indicating that other (additional) factors may be involved in

  11. Justification for recommended uncertainties

    International Nuclear Information System (INIS)

    Pronyaev, V.G.; Badikov, S.A.; Carlson, A.D.

    2007-01-01

    The uncertainties obtained in an earlier standards evaluation were considered to be unrealistically low by experts of the US Cross Section Evaluation Working Group (CSEWG). Therefore, the CSEWG Standards Subcommittee replaced the covariance matrices of evaluated uncertainties by expanded percentage errors that were assigned to the data over wide energy groups. There are a number of reasons that might lead to low uncertainties of the evaluated data: Underestimation of the correlations existing between the results of different measurements; The presence of unrecognized systematic uncertainties in the experimental data can lead to biases in the evaluated data as well as to underestimations of the resulting uncertainties; Uncertainties for correlated data cannot only be characterized by percentage uncertainties or variances. Covariances between evaluated value at 0.2 MeV and other points obtained in model (RAC R matrix and PADE2 analytical expansion) and non-model (GMA) fits of the 6 Li(n,t) TEST1 data and the correlation coefficients are presented and covariances between the evaluated value at 0.045 MeV and other points (along the line or column of the matrix) as obtained in EDA and RAC R matrix fits of the data available for reactions that pass through the formation of the 7 Li system are discussed. The GMA fit with the GMA database is shown for comparison. The following diagrams are discussed: Percentage uncertainties of the evaluated cross section for the 6 Li(n,t) reaction and the for the 235 U(n,f) reaction; estimation given by CSEWG experts; GMA result with full GMA database, including experimental data for the 6 Li(n,t), 6 Li(n,n) and 6 Li(n,total) reactions; uncertainties in the GMA combined fit for the standards; EDA and RAC R matrix results, respectively. Uncertainties of absolute and 252 Cf fission spectrum averaged cross section measurements, and deviations between measured and evaluated values for 235 U(n,f) cross-sections in the neutron energy range 1

  12. Short vegetal-fiber reinforced HDPE—A study of electron-beam radiation treatment effects on mechanical and morphological properties

    International Nuclear Information System (INIS)

    Ferreira, Maiara S.; Sartori, Mariana N.; Oliveira, Rene R.; Guven, Olgun; Moura, Esperidiana A.B.

    2014-01-01

    Graphical abstract: - Highlights: • HDPE reinforced with short piassava fiber composites were prepared by melt-mixing processing. • Glycidyl methacrylate (GMA) was tested as a radiation cross-linking agent. • The materials were irradiated with 100 and 200 kGy using a 1.5 MeV electron beam accelerator, at room temperature in presence of air. • The better interfacial adhesion between fiber and HDPE matrix was observed for composites with GMA addition irradiated with radiation dose of 200 kGy. - Abstract: The effects of electron-beam radiation treatment on fiber-matrix adhesion and mechanical properties of short piassava fibers reinforced high density polyethylene (HDPE) matrix were studied. Glycidyl methacrylate (GMA) was added at 2.5% and 5.0% (on piassava fiber wt) as a cross-linking agent and the effects upon the properties of the resulting composites treated by electron-beam radiation were also examined. HDPE reinforced with short piassava fiber composites was prepared by melt-mixing processing, using a twin screw extruder machine. The materials were irradiated with 100 and 200 kGy using a 1.5 MeV electron beam accelerator, at room temperature in presence of air. Material samples were submitted to mechanical and thermo-mechanical tests and SEM analyses. Correlation between properties was discussed. The comparison of mechanical and thermo-mechanical properties of the composites showed that electron-beam radiation treatment produced a significant improvement in mechanical properties, when compared with the non-irradiated composite sample and neat HDPE. Scanning electron microscopy (SEM) studies of the composite failure surfaces indicated that there was an improved adhesion between fiber and matrix. Examination of the failure surfaces indicated dependence of the interfacial adhesion upon the radiation dose and GMA content. Better interfacial adhesion between fiber and HDPE matrix was observed for composites with 5.0% GMA addition and treated with electron

  13. Short vegetal-fiber reinforced HDPE—A study of electron-beam radiation treatment effects on mechanical and morphological properties

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira, Maiara S.; Sartori, Mariana N.; Oliveira, Rene R. [Nuclear and Energy Research Institute, IPEN-CNEN/SP, Av. Prof. Lineu Prestes 2242, zip code 05508-000 São Paulo, SP (Brazil); Guven, Olgun [Hacettepe University, Department of Chemistry, Polymer Chemistry Division, Beytepe, zip code 06800 Ankara (Turkey); Moura, Esperidiana A.B., E-mail: eabmoura@ipen.br [Nuclear and Energy Research Institute, IPEN-CNEN/SP, Av. Prof. Lineu Prestes 2242, zip code 05508-000 São Paulo, SP (Brazil)

    2014-08-15

    Graphical abstract: - Highlights: • HDPE reinforced with short piassava fiber composites were prepared by melt-mixing processing. • Glycidyl methacrylate (GMA) was tested as a radiation cross-linking agent. • The materials were irradiated with 100 and 200 kGy using a 1.5 MeV electron beam accelerator, at room temperature in presence of air. • The better interfacial adhesion between fiber and HDPE matrix was observed for composites with GMA addition irradiated with radiation dose of 200 kGy. - Abstract: The effects of electron-beam radiation treatment on fiber-matrix adhesion and mechanical properties of short piassava fibers reinforced high density polyethylene (HDPE) matrix were studied. Glycidyl methacrylate (GMA) was added at 2.5% and 5.0% (on piassava fiber wt) as a cross-linking agent and the effects upon the properties of the resulting composites treated by electron-beam radiation were also examined. HDPE reinforced with short piassava fiber composites was prepared by melt-mixing processing, using a twin screw extruder machine. The materials were irradiated with 100 and 200 kGy using a 1.5 MeV electron beam accelerator, at room temperature in presence of air. Material samples were submitted to mechanical and thermo-mechanical tests and SEM analyses. Correlation between properties was discussed. The comparison of mechanical and thermo-mechanical properties of the composites showed that electron-beam radiation treatment produced a significant improvement in mechanical properties, when compared with the non-irradiated composite sample and neat HDPE. Scanning electron microscopy (SEM) studies of the composite failure surfaces indicated that there was an improved adhesion between fiber and matrix. Examination of the failure surfaces indicated dependence of the interfacial adhesion upon the radiation dose and GMA content. Better interfacial adhesion between fiber and HDPE matrix was observed for composites with 5.0% GMA addition and treated with electron

  14. 1999 Annual report

    International Nuclear Information System (INIS)

    2000-01-01

    In 1999, GMA executed a major shift in its business strategy and operations by selling its geophysical and geological software assets and by entering into broad based technology markets with potential sales growth in North America and internationally. The decision to diversify the company's client base followed the slowdown in the oil and gas industry in 1998 and 1999, forcing many of the company's clients to cut budgets in order to survive. The new business strategy enables GMA to concentrate on delivering software and service solutions across a wide-range of non-cyclical industries, giving the company greater access to growth markets, less susceptibility to industry down cycles and increased applications of research and development results. To give effect to the new strategy, GMA in 1999 acquired 100 per cent of a high volume virtual data management company (NRI Online Inc), 100 per cent of a newspaper circulation management software company (NTI Newspaper Technologies Inc). GMA also acquired the remaining outstanding shares of a private Alberta company which developed petrophysical software for the oil and gas industry. Through NRI's Computerized On-Line Interactive Network (COIN) GMA, to be renamed Netdriven Solutions Inc., intends to enter the Canadian oil and gas seismic data niche market by providing storage and management of large volume data sets in an on-line network environment, with high speed fibre optic communications links. Current NRI clients include Talisman Energy, Mobil Oil, Anderson Exploration, Suncor Energy , and others. The long-term goal is to expand NRI's oil and gas client base from Calgary to other national and international oil and gas regions. GMA had revenues from its combined operation in Canada, the USA and Europe of $ 5.7 million in 1999, derived from a combination of geophysical and geological software sales, maintenance contracts and geophysical consulting services. Revenues from software sale alone are down, due to the cutbacks

  15. Mask manufacturing improvement through capability definition and bottleneck line management

    Science.gov (United States)

    Strott, Al

    1994-02-01

    In 1989, Intel's internal mask operation limited itself to research and development activities and re-inspection and pellicle application of externally manufactured masks. Recognizing the rising capital cost of mask manufacturing at the leading edge, Intel's Mask Operation management decided to offset some of these costs by manufacturing more masks internally. This was the beginning of the challenge they set to manufacture at least 50% of Intel's mask volume internally, at world class performance levels. The first step in responding to this challenge was the completion of a comprehensive operation capability analysis. A series of bottleneck improvements by focus teams resulted in an average cycle time improvement to less than five days on all product and less than two days on critical products.

  16. Cost/Performance Ratio Achieved by Using a Commodity-Based Cluster

    Science.gov (United States)

    Lopez, Isaac

    2001-01-01

    Researchers at the NASA Glenn Research Center acquired a commodity cluster based on Intel Corporation processors to compare its performance with a traditional UNIX cluster in the execution of aeropropulsion applications. Since the cost differential of the clusters was significant, a cost/performance ratio was calculated. After executing a propulsion application on both clusters, the researchers demonstrated a 9.4 cost/performance ratio in favor of the Intel-based cluster. These researchers utilize the Aeroshark cluster as one of the primary testbeds for developing NPSS parallel application codes and system software. The Aero-shark cluster provides 64 Intel Pentium II 400-MHz processors, housed in 32 nodes. Recently, APNASA - a code developed by a Government/industry team for the design and analysis of turbomachinery systems was used for a simulation on Glenn's Aeroshark cluster.

  17. Characterization of gas metal arc welded hot rolled DP600 steel

    Energy Technology Data Exchange (ETDEWEB)

    Mukherjee, K.; Ramazani, A.; Yang, L.; Prahl, U.; Bleck, W. [RWTH Aachen University, Institute for Ferrous Metallurgy (IEHK) (Germany); Reisgen, U.; Schleser, M.; Abdurakhmanov, A. [RWTH Aachen University, Welding and Joining Institute (ISF) (Germany)

    2011-12-15

    Dual-phase (DP) steels are suitable candidates for automotive applications due to their high strength and ductility. These advanced mechanical properties result from the special microstructure of the DP steel with 5{proportional_to}20% martensite phase in a soft ferrite matrix. However, during welding, which is an important process in automotive industry, this special microstructure is destroyed. In this research the characterization of Gas Metal Arc (GMA) welded joining zones was performed by optical microscopy and hardness mapping. Tensile tests were also performed keeping the welded portion in the gauge length. Scanning Electron Microscopy (SEM) was used for the fracture investigation. From the characterization and tensile tests, the soften zones were found, which are caused by the tempered martensite and larger ferrite grain size than that in base metal. Furthermore, GMA welding make a large Heat Affected Zone (HAZ). (Copyright copyright 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  18. Comparing Efficacy of Instructional Approaches to Develop Environmental Awareness Among School Students

    Directory of Open Access Journals (Sweden)

    Doris D’Souza

    2014-12-01

    Full Text Available This study aims to compare efficacy of self-learning, audiovisual, and fun activity instructional approaches among school students of Patna, the capital city of Bihar state of India, to develop environmental awareness. The study participants include 144 randomly selected students (72 girls and 72 boys from eight different schools of Patna. During a weeklong environmental awareness program, students were instructed using above three approaches of instruction. Data have been analyzed by using linear regression. Regression was carried out to eliminate the effect of general mental ability (GMA scores. The results suggest about overall superiority of fun activity approach over other approaches tested in the present study. However, awareness gain has been significant among the students with high GMA when instructed through audiovisual approach.

  19. Characterization and equalization of the AC responses of the corrector magnets for the APS local orbit feedback system

    Energy Technology Data Exchange (ETDEWEB)

    Doose, C.; Kim, S.H.

    1997-08-01

    Local feedback for the APS storage ring uses local bumps to control the position and angle of the positron beam through each x-ray source point. Induced eddy currents in the aluminum vacuum chamber dominate the AC characteristics of the corrector magnetic fields. Small differences in the geometries at each magnet location change the eddy current effects and result in bump closure errors which must be reduced in order to minimize the coupling between each of the many local loops and the global control loop. By a combination of flux-damping coils, flux-shielding copper sheets, and a set of steel laminations for end-flux clamping, the differences of the eddy current effects between two corrector magnets were reduced from 0.18 Gm/A to 0.035 Gm/A in the frequency span of 0.1-100 Hz.

  20. Controlled release of potassium chloride from radiation-polymerized copolymer matrices

    International Nuclear Information System (INIS)

    Yoshida, Masaru; Kumakura, Minoru; Kaetsu, Isao

    1979-01-01

    Release behavior of potassium chloride (KCl) from the flat circular copolymer composites, obtained by radiation-induced polymerization at low temperatures, was studied. The release rate agreed with the first-order kinetics based on the Noyes-Whitney equation in relation to the swelling of the composites. Release profiles of KCl from copolymer composites was affected by monomer composition between hydroxyethyl acrylate (HEA) and polyfunctional glass-forming monomers such as 2-hydroxyethyl methacrylate (HEMA), diethylene glycol dimethacrylate (DGDA), and trimethylolpropane trimethacrylate (TMPT) owing to change of swelling property of copolymers. The release rate decreased at HEA-poor composition in any system. In the case of hydrophobic comonomer system such as glycidyl methacrylate (GMA) and DGDA, release profile of KCl showed a minimum at 50% GMA-50% DGDA monomer composition. (author)

  1. Observation of damage process in RC beams under cucle bending by acoustic emission

    International Nuclear Information System (INIS)

    Shigeishi, Mitsuhiro; Ohtsu, Masayasu; Tsuji, Nobuyuki; Yasuoka, Daisuke

    1997-01-01

    Reinforced concrete (RC) structures are generally applied to construction of buildings and bridges, and are imposed on cyclic loading incessantly. It is considered that detected acoustic emission (AE) waveforms are associated with the damage degree and the fracture mechanisms of RC structures. Therefor, the cyclic bending tests are applied to damaged RC beam specimens. To evaluate the interior of the damaged RC beams, the AE source kinematics are determined by 'SiGMA' procedure for AE moment tensor analysis. By using 'SiGMA' procedure, AE source kinematics, such as source locations, crack types, crack orientations and crack motions, can be identified. The results show the applicability to observation of the fracture process under cyclic bending load and evaluation the degree of damage of RC beam.

  2. New membranes obtained by grafted irradiated PVDF foils

    International Nuclear Information System (INIS)

    Mazzei, R.; García Bermúdez, G.; Camporotondi, D.E.; Arbeitman, C.

    2012-01-01

    The present work describes a new method to produce membranes of poly(Acrylic-acid-Xmonomer) using the grafting procedure. PVDF foils irradiated with Ar + beam with energies between 30 and 150 keV were employed as substratum. Different combinations of monomers in water solutions were used: acrylic acid (AAc); acrylic acid–glycidyl methacrylate (AAc–GMA); acrylic acid–styrene (AAc–S), acrylic acid-N-isopropyl acrylamide (AAc–NIPAAm) and acrylic acid-N-isopropyl acrylamide–glycidyl methacrylate (AAc-NIPAAm–GMA). A large percentage of grafting results for specific values of: ion fluence and energy, AAc and sulfuric acid concentration, and different substrata PVDF polymorphous (alpha or beta). At a particular time of the grafting process, the poly(AAc-Xmonomer) membranes detach from the substratum and continue their grafting in the solution. This method is useful to produce increased replicated membranes of the irradiated original surface.

  3. Flexural behaviour of post-cured composites at oral-simulating temperatures.

    Science.gov (United States)

    Ho, C T; Vijayaraghavan, T V; Lee, S Y; Tsai, A; Huang, H M; Pan, L C

    2001-07-01

    Post-curing treatments have been known to improve the mechanical stability of visible light-cured composites. After individual post-curing treatment, the flexural strength (FS) of four commercial direct/indirect placement composite materials which differ greatly in composition [oligocarbonate dimethacrylate (OCDMA)-based Conquest C & B (CQT), Bisphenol-A glycidyl dimethacrylate (BisGMA)-based Charisma, urethane dimethacrylate (UDMA)-based Concept (CCT), and BisGMA/UDMA-based Dentacolor] was evaluated under water in the temperature range of 12-50 degrees C. A control series was tested in air at room temperature (25 +/- 1 degrees C). Data were analysed using ANOVA and Duncan's test. Flexural strengths overall decreased (20-40%, P OCDMA-based materials. Post-cured composites can be significantly affected by exposure to oral environments. Different composition determines the degree of influence.

  4. A study of ethanol production of yeast cells immobilized with polymer carrier produced by radiation polymerization

    International Nuclear Information System (INIS)

    Lu Zhaoxin; Fujimura, Takashi

    1993-01-01

    Polymer carriers, poly(hydroxyethyl acrylate(HEA)-methoxy polyethylene glycol methylacrylate (M-23G)) and poly(hydroxyethyl acrylate(HEA)-glycidyl methylacrylate (GMA)) used for the immobilization of yeast cells were prepared by radiation polymerization at low temperature. Yeast cells were immobilized through adhesion and multiplication of yeast cells. The ethanol productivity of immobilized yeast cells with these carriers was related to the monomer composition of polymers and the optimum monomer composition was 20%:10% in poly(HEA-M-23G) and 17%:6% in poly(HEA-GMA). In this case, the ethanol productivity of immobilized yeast cells was about 4 times that of cells in free system. The relationship between the activity of immobilized yeast cells and the water content of the polymer carrier were also discussed. (author)

  5. STUDY OF COATINGS OBTAINED FROM ALLOY Fe-Mn-C-B-Si-Ni-Cr

    Directory of Open Access Journals (Sweden)

    Mychajło Paszeczko

    2016-09-01

    Full Text Available Tribological behaviour of coatings obtained from eutectic alloy Fe-Mn-C-B-Si-Ni-Cr was studied. The coatings were obtained by the method of gas metal arc welding (GMA with use of powder wire. GMA welding method is widely used for the regeneration of machine parts. Eutectic Fe-Mn-C-B-Si-Ni-Cr alloys can be used to obtain high quality coatings resistant to wear and corrosion. Pin-on-disk dry sliding wear tests at sliding speeds 0.4 m/s and under load 10 MPa were conducted for pin specimens. During friction a typical tribological behavior was observed. The mechanism of wear was mechanical-chemical.

  6. Camas drenantes bajo las líneas de drenaje de la zona metropolitana de Guadalajara (ZMG

    Directory of Open Access Journals (Sweden)

    Carlos Alejandro Vázquez Ortiz

    2013-10-01

    Full Text Available This paper presented a modified construction procedure for interior drainage lines and municipal network. One of the problems that affect the roads and buildings of the GMA is the failure of this structure due to tunnels in the ground support. This is caused by water leaks in the drains lines due to the water pressure flow that came from the soil piping due to the saturation of the ground support and consequently decreasing the resistance. In this paper it has been proposed the inclusion of a drainage bed, composed of a layer of pumitic sand, which could compromise the main GMA. This material develops high permeability and good resistance if it is compacted. Also, it has been included the installation of grids at certain distance to avoid the loss of fine particles due to piping. Moreover, a polyethylene layer has been added to the drainage bed, which prevents water leaking thought the ground support.

  7. Grafting of glycidyl methacrylate/styrene onto polyvinyldine fluoride membranes for proton exchange fuel cell

    International Nuclear Information System (INIS)

    Abdel-Hady, E.E.; El-Toony, M.M.; Abdel-Hamed, M.O.

    2013-01-01

    Simultaneous gamma irradiation was used effectively for grafting facilitation of glycidyl methacrylate (GMA) and styrene (Sty) onto polyvinylidine fluoride (PVDF). Grafting percent was 122 when monomers ratio are 30% Sty and 70% GMA at 20 KGy gamma irradiation dose. Characterization of the membrane was performed using FT-IR, ion exchange capacity (IEC), water uptake. Mechanical behavior such as tensile strength was studied while morphological structure of the membrane was carried out by scan electron microscope (SEM). The membrane with degree of grafting 122% showed higher IEC (1.2 m mol/cm) than those of Nafion membrane with corresponding proton conductivity of 5.7 × 10 −2 S/cm similar to it. Operating the fuel cell unit showed higher voltage of the prepared membranes than that of Nafion 211. The prepared membranes stability for 300 h work approved their applicability from the cost benefit point of view

  8. Development of a Plasma Streaming System for the Mirror Fusion Test Facility

    International Nuclear Information System (INIS)

    Holdsworth, T.; Clark, R.N.; McCotter, R.E.; Rossow, T.L.; Cruz, G.E.

    1979-01-01

    The Plasma Streaming System (PSS) is an essential portion of the Mirror Fusion Test Facility (MFTF), scheduled for completion in October 1981. The PSS will develop a plasma density of at least 2 x 10 12 particles/cm 3 at the MFTF magnet centerline by injecting particles along the field lines. The plasma will have a midplane plasma radius as large as 40 cm with variable plasma particle energy and beam geometry. Minimum amounts of impurities will be injected, with emphasis on minimizing high Z materials. Each of the 60 PSS units will consist of a gun magnet assembly (GMA) and a power supply. Each GMA consists of a plasma streaming gun, a pulse magnet that provides variable beam shaping, and a fast reaction pulse gas valve

  9. Studies on novel radiopaque methyl methacrylate: glycidyl methacrylate based polymer for biomedical applications.

    Science.gov (United States)

    Dawlee, S; Jayakrishnan, A; Jayabalan, M

    2009-12-01

    A new class of radiopaque copolymer using methyl methacrylate (MMA) and glycidyl methacrylate (GMA) monomers was synthesized and characterized. The copolymer was made radiopaque by the epoxide ring opening of GMA using the catalyst o-phenylenediamine and the subsequent covalent attachment of elemental iodine. The copolymer was characterized by Fourier transform infrared (FTIR) spectra, energy dispersive X-ray analysis using environmental scanning electron microscope (EDAX), thermogravimetric analysis (TGA), and differential scanning calorimetry (DSC). X-ray visibility of the copolymer was checked by X-radiography. Blood compatibility and cytotoxicity of the newly synthesized copolymer were also evaluated. The iodinated copolymer was thermally stable, blood compatible, non-cytotoxic, and highly radiopaque. The presence of bulky iodine group created a new copolymer with modified properties for potential use in biomedical applications.

  10. Separation of PCR-ready DNA from dairy products using magnetic hydrophilic microspheres and poly(ethylene glycol)-NaCl water solutions

    Energy Technology Data Exchange (ETDEWEB)

    Rittich, Bohuslav [Masaryk University, Faculty of Science, Institute of Experimental Biology, Tvrdeho 14, CZ-611 37 Brno (Czech Republic); Brno University of Technology, Faculty of Chemistry, Institute of Food Science and Biotechnology, Purkynova 464/118, CZ-612 00 Brno (Czech Republic)], E-mail: rittich@sci.muni.cz; Spanova, Alena [Masaryk University, Faculty of Science, Institute of Experimental Biology, Tvrdeho 14, CZ-611 37 Brno (Czech Republic); Brno University of Technology, Faculty of Chemistry, Institute of Food Science and Biotechnology, Purkynova 464/118, CZ-612 00 Brno (Czech Republic); Salek, Petr [Brno University of Technology, Faculty of Chemistry, Institute of Food Science and Biotechnology, Purkynova 464/118, CZ-612 00 Brno (Czech Republic); Nemcova, Petra [Masaryk University, Faculty of Science, Institute of Experimental Biology, Tvrdeho 14, CZ-611 37 Brno (Czech Republic); Trachtova, Stepanka [Brno University of Technology, Faculty of Chemistry, Institute of Food Science and Biotechnology, Purkynova 464/118, CZ-612 00 Brno (Czech Republic); Horak, Daniel [Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic, Heyrovsky Sq. 2, CZ-162 06 Prague (Czech Republic)

    2009-05-15

    Carboxyl group-containing magnetic nonporous poly(2-hydroxyethyl methacrylate-co-glycidyl methacrylate) (P(HEMA-co-GMA)) and magnetic glass microspheres were used for the isolation of bacterial DNA. P(HEMA-co-GMA) microspheres were prepared by the dispersion polymerization in toluene/2-methylpropan-1-ol mixture in the presence of magnetite nanoparticles obtained by coprecipitation of Fe(II) and Fe(III) salts with ammonium hydroxide. Carboxyl groups were then introduced by oxidation of the microspheres with potassium permanganate. The most extensive DNA recovery was achieved at PEG 6000 concentrations of 12% or 16% and 2 M NaCl. The method proposed was used for bacterial DNA isolation from different dairy products containing Bifidobacterium and Lactobacillus cells. The presence of target DNA and the quality of isolated DNA were checked by polymerase chain reaction (PCR) amplification with specific primers.

  11. New membranes obtained by grafted irradiated PVDF foils

    Energy Technology Data Exchange (ETDEWEB)

    Mazzei, R. [Unidad de Actividades Tecnologicas y Agropecuarias, Laboratorio de Polimeros, Comision Nacional de Energia Atomica, Buenos Aires (Argentina); Universidad Tecnologica Nacional Facultad Regional, Buenos Aires (Argentina); Garcia Bermudez, G. [Gerencia de Investigacion y Aplicaciones, Laboratorio Tandar, Comision Nacional de Energia Atomica, Buenos Aires (Argentina); Escuela de Ciencia y Tecnologia, Universidad Nacional de General San Martin, Buenos Aires (Argentina); Consejo Nacional de Investigaciones Cientificas y Tecnicas, Buenos Aires (Argentina); Camporotondi, D.E., E-mail: camporotondi@cae.cnea.gov.ar [Unidad de Actividades Tecnologicas y Agropecuarias, Laboratorio de Polimeros, Comision Nacional de Energia Atomica, Buenos Aires (Argentina); Arbeitman, C. [Gerencia de Investigacion y Aplicaciones, Laboratorio Tandar, Comision Nacional de Energia Atomica, Buenos Aires (Argentina); Consejo Nacional de Investigaciones Cientificas y Tecnicas, Buenos Aires (Argentina); and others

    2012-09-15

    The present work describes a new method to produce membranes of poly(Acrylic-acid-Xmonomer) using the grafting procedure. PVDF foils irradiated with Ar{sup +} beam with energies between 30 and 150 keV were employed as substratum. Different combinations of monomers in water solutions were used: acrylic acid (AAc); acrylic acid-glycidyl methacrylate (AAc-GMA); acrylic acid-styrene (AAc-S), acrylic acid-N-isopropyl acrylamide (AAc-NIPAAm) and acrylic acid-N-isopropyl acrylamide-glycidyl methacrylate (AAc-NIPAAm-GMA). A large percentage of grafting results for specific values of: ion fluence and energy, AAc and sulfuric acid concentration, and different substrata PVDF polymorphous (alpha or beta). At a particular time of the grafting process, the poly(AAc-Xmonomer) membranes detach from the substratum and continue their grafting in the solution. This method is useful to produce increased replicated membranes of the irradiated original surface.

  12. How Managers' everyday decisions create or destroy your company's strategy.

    Science.gov (United States)

    Bower, Joseph L; Gilbert, Clark G

    2007-02-01

    Senior executives have long been frustrated by the disconnection between the plans and strategies they devise and the actual behavior of the managers throughout the company. This article approaches the problem from the ground up, recognizing that every time a manager allocates resources, that decision moves the company either into or out of alignment with its announced strategy. A well-known story--Intel's exit from the memory business--illustrates this point. When discussing what businesses Intel should be in, Andy Grove asked Gordon Moore what they would do if Intel were a company that they had just acquired. When Moore answered, "Get out of memory," they decided to do just that. It turned out, though, that Intel's revenues from memory were by this time only 4% of total sales. Intel's lower-level managers had already exited the business. What Intel hadn't done was to shut down the flow of research funding into memory (which was still eating up one-third of all research expenditures); nor had the company announced its exit to the outside world. Because divisional and operating managers-as well as customers and capital markets-have such a powerful impact on the realized strategy of the firm, senior management might consider focusing less on the company's formal strategy and more on the processes by which the company allocates resources. Top managers must know the track record of the people who are making resource allocation proposals; recognize the strategic issues at stake; reach down to operational managers to work across division lines; frame resource questions to reflect the corporate perspective, especially when large sums of money are involved and conditions are highly uncertain; and create a new context that allows top executives to circumvent the regular resource allocation process when necessary.

  13. A comparison of cytotoxicity and oxidative stress from welding fumes generated with a new nickel-, copper-based consumable versus mild and stainless steel-based welding in RAW 264.7 mouse macrophages.

    Science.gov (United States)

    Badding, Melissa A; Fix, Natalie R; Antonini, James M; Leonard, Stephen S

    2014-01-01

    Welding processes that generate fumes containing toxic metals, such as hexavalent chromium (Cr(VI)), manganese (Mn), and nickel (Ni), have been implicated in lung injury, inflammation, and lung tumor promotion in animal models. While federal regulations have reduced permissible worker exposure limits to Cr(VI), this is not always practical considering that welders may work in confined spaces and exhaust ventilation may be ineffective. Thus, there has been a recent initiative to minimize the potentially hazardous components in welding materials by developing new consumables containing much less Cr(VI) and Mn. A new nickel (Ni) and copper (Cu)-based material (Ni-Cu WF) is being suggested as a safer alternative to stainless steel consumables; however, its adverse cellular effects have not been studied. This study compared the cytotoxic effects of the newly developed Ni-Cu WF with two well-characterized welding fumes, collected from gas metal arc welding using mild steel (GMA-MS) or stainless steel (GMA-SS) electrodes. RAW 264.7 mouse macrophages were exposed to the three welding fumes at two doses (50 µg/ml and 250 µg/ml) for up to 24 hours. Cell viability, reactive oxygen species (ROS) production, phagocytic function, and cytokine production were examined. The GMA-MS and GMA-SS samples were found to be more reactive in terms of ROS production compared to the Ni-Cu WF. However, the fumes from this new material were more cytotoxic, inducing cell death and mitochondrial dysfunction at a lower dose. Additionally, pre-treatment with Ni-Cu WF particles impaired the ability of cells to phagocytize E. coli, suggesting macrophage dysfunction. Thus, the toxic cellular responses to welding fumes are largely due to the metal composition. The results also suggest that reducing Cr(VI) and Mn in the generated fume by increasing the concentration of other metals (e.g., Ni, Cu) may not necessarily improve welder safety.

  14. Evaluation of the molecular mechanisms associated with cytotoxicity and inflammation after pulmonary exposure to different metal-rich welding particles.

    Science.gov (United States)

    Shoeb, Mohammad; Kodali, Vamsi; Farris, Breanne; Bishop, Lindsey M; Meighan, Terence; Salmen, Rebecca; Eye, Tracy; Roberts, Jenny R; Zeidler-Erdely, Patti; Erdely, Aaron; Antonini, James M

    2017-08-01

    Welding generates a complex aerosol of incidental nanoparticles and cytotoxic metals, such as chromium (Cr), manganese (Mn), nickel (Ni), and iron (Fe). The goal was to use both in vivo and in vitro methodologies to determine the mechanisms by which different welding fumes may damage the lungs. Sprague-Dawley rats were treated by intratracheal instillation (ITI) with 2.0 mg of gas metal arc-mild steel (GMA-MS) or manual metal arc-stainless steel (MMA-SS) fumes or saline (vehicle control). At 1, 3, and 10 days, bronchoalveolar lavage (BAL) was performed to measure lung toxicity. To assess molecular mechanisms of cytotoxicity, RAW264.7 cells were exposed to both welding fumes for 24 h (0-100 μg/ml). Fume composition was different: MMA-SS (41% Fe, 29% Cr, 17% Mn, 3% Ni) versus GMA-MS (85% Fe, 14% Mn). BAL indicators of lung injury and inflammation were increased by MMA-SS at all time points and by GMA-MS at 3 and 10 days after exposure. RAW264.7 cells exposed to MMA-SS had elevated generation of reactive oxygen species (ROS), protein-HNE (P-HNE) adduct formation, activation of ERK1/2, and expression of cyclooxygenase-2 (COX-2) compared to GMA-MS and control. Increased generation of ROS due to MMA-SS exposure was confirmed by increased expression of Nrf2 and heme oxygenase-1 (HO-1). Results of in vitro studies provide evidence that stainless steel welding fume mediate inflammatory responses via activation of ROS/P-HNE/ERK1/2/Nrf2 signaling pathways. These findings were corroborated by elevated expression of COX-2, Nrf2, and HO-1 in homogenized lung tissue collected 1 day after in vivo exposure.

  15. Cardiovascular effects in rats after intratracheal instillation of metal welding particles.

    Science.gov (United States)

    Zheng, Wen; Antonini, James M; Lin, Yen-Chang; Roberts, Jenny R; Kashon, Michael L; Castranova, Vincent; Kan, Hong

    2015-01-01

    Studies have indicated that pulmonary exposure to welding fumes can induce a series of adverse effects in the respiratory system, including infection, bronchitis, siderosis and decreased pulmonary function. Recent clinical and epidemiological studies have found that pulmonary exposure to welding fumes is also associated with a higher incidence of cardiovascular events. However, there is insufficient evidence to confirm a direct effect of welding fumes on the cardiovascular system. The present study investigated the effects of pulmonary exposure to welding fumes on the heart and the vascular system in rats. Two chemically distinct welding fumes generated from manual metal arc-hard surfacing (MMA-HS) and gas metal arc-mild steel (GMA-MS) welding were tested. Three groups of rats were instilled intratracheally with MMA-HS (2 mg/rat), GMA-MS (2 mg/rat) or saline as control once a week for seven weeks. On days 1 and 7 after the last treatment, basal cardiovascular function and the cardiovascular response to increasing doses of adrenoreceptor agonists were assessed. MMA-HS treatment reduced the basal levels of left ventricle end-systolic pressure and dP/dt(max) at 1 day post-treatment, and decreased dP/dt(min) in response to isoproterenol (ISO) at 7 days post-treatment. Unlike MMA-HS, GMA-MS only affected left ventricular end-diastolic pressure in response to ISO at 7 days post-treatment. Treatment with MMA-HS or GMA-MS did not alter heart rate and blood pressure. Our findings suggest that exposure to different welding fumes can induce different adverse effects on the cardiovascular system, and that cardiac contractility may be a sensitive indicator of cardiovascular dysfunction.

  16. Finding of No Significant Impact for the Missouri River Recovery Program Lower Little Sioux Bend Shallow Water Habitat Construction Project

    Science.gov (United States)

    2011-07-01

    when it is used or managed for food or fiber, to include timber products, fruit, nuts, grapes, grain, forage, oil seed, fish and meat , poultry and dairy...entirely on the Deer Island State Game Management Area (GMA) managed by the Iowa Department of Natural Resources (IDNR). Alternatives Through the...Quality (NDEQ), Nebraska Game and Parks Commission (NGPC), and USFWS, the Draft Project Implementation Report (PIR) was posted for comment on the MRRP

  17. Photodegradable neutral-cationic brush block copolymers for nonviral gene delivery.

    Science.gov (United States)

    Hu, Xianglong; Li, Yang; Liu, Tao; Zhang, Guoying; Liu, Shiyong

    2014-08-01

    We report on the fabrication of a photodegradable gene-delivery vector based on PEO-b-P(GMA-g-PDMAEMA) neutral-cationic brush block copolymers that possess cationic poly(N,N-dimethylaminoethyl methacrylate) (PDMAEMA) brushes for DNA compaction, poly(ethylene oxide) (PEO) as a hydrophilic block, and poly(glycidyl methacrylate) (PGMA) as the backbone. The PEO-b-P(GMA-g-PDMAEMA) copolymers were synthesized through the combination of reversible addition-fragmentation transfer (RAFT) polymerization and postmodification. A photocleavable PEO-based macroRAFT agent was first synthesized; next, the PEO-b-PGMA block copolymer was prepared by RAFT polymerization of GMA; this was followed by a click reaction to introduce the RAFT initiators on the side chains of the PGMA block; then, RAFT polymerization of DMAEMA afforded the PEO-b-P(GMA-g-PDMAEMA) copolymer. The obtained neutral-cationic brush block copolymer could effectively complex plasmid DNA (pDNA) into nanoparticles at an N/P ratio (i.e., the number of nitrogen residues per DNA phosphate) of 4. Upon UV irradiation, pDNA could be released owing to cleavage of the pDNA-binding cationic PDMAEMA side chains as well as the nitrobenzyl ester linkages at the diblock junction point. In addition, in vitro gene transfection results demonstrated that the polyplexes could be effectively internalized by cells with good transfection efficiency, and the UV irradiation protocol could considerably enhance the efficiency of gene transfection. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. Polypropylene fibers modified by plasma treatment for preparation of Ag nanoparticles.

    Science.gov (United States)

    Tseng, Chun-Hao; Wang, Cheng-Chien; Chen, Chuh-Yung

    2006-03-09

    A novel method for preparing poly(propylene-graft-2-methacrylic acid 3-(bis-carboxymethylamino)-2-hydroxy-propyl ester)-silver fibers (PPG-IAg fibers) by plasma-induced grafting polymerization is presented in this study. The chelating groups, -N(CH2COO-)2 (GMA-IDA), on the surface of the PPG-I fibers are the coordination sites for chelating silver ions. At these sites, Ag nanoparticles were grown first by reduction with UV light with a wavelength of 366 nm, and second, through immersion in a 24% formaldehyde solution with pH values set variously at 2, 5, 8, and 11. The characteristics of the PPG-I fibers with differing durations of plasma treatment were monitored by using a Fourier transform infrared (FT-IR) spectroscope. Scanning electronic microscopy (SEM) and elemental analysis show that the percentage of GMA-IDA grafted onto PP fiber reaches a maximum when the plasma treatment time is 3 min. Plasma treatment time beyond a certain length of time results in an abundance of free radicals and causes considerable cross-linking on the fiber surface which thus decreases the extent of grafting. Moreover, the crystalline phase of Ag nanoparticles is identified by using X-ray diffraction (XRD). When the PPG-I fibers are reduced by the UV light method, SEM and TEM microscopes reveal that the size of the Ag nanoparticles on the fiber surface decreases significantly with the increase of pH values in aqueous solutions. Notably, in the reduction of formaldehyde solution, the particle size of Ag nanoparticles reaches a minimum at the lowest pH value. The TEM observations show that Ag nanoparticles are distributed both in the exterior and interior of the grafting layer. In addition, under high pH values the distribution of the Ag nanoparticles permeate more deeply in the GMA-IDA grafting layer due to the swelling effect of the GMA-IDA polymer.

  19. Separation of PCR-ready DNA from dairy products using magnetic hydrophilic microspheres and poly(ethylene glycol)-NaCl water solutions

    Czech Academy of Sciences Publication Activity Database

    Rittich, B.; Španová, A.; Šálek, P.; Němcová, P.; Trachtová, Š.; Horák, Daniel

    2009-01-01

    Roč. 321, č. 10 (2009), s. 1667-1670 ISSN 0304-8853. [International Conference on Scientific and Clinical Applications of Magnetic Carriers /7./. Vancouver, 20.05.2008-24.05.2008] R&D Projects: GA ČR GA203/09/1242 Institutional research plan: CEZ:AV0Z40500505 Keywords : magnetic microsphere * P(HEMA-co-GMA) * DNA isolation Subject RIV: CD - Macromolecular Chemistry Impact factor: 1.204, year: 2009

  20. Triggers of Chinese Economic Coercion

    Science.gov (United States)

    2014-09-01

    2007 Angela Merkel–Dalai Lama Meeting ..............................70 2. The 2008 Nicolas Sarkozy–Dalai Lama Meeting ............................72 E...president Nicolas Sarkozy,35 Reilly nevertheless asserts that that while a mixture of statecraft tactics will continue, carrots are the first weapon of...144 Kim Tan and Anita O. Legaspi, “PHL Says It Will ‘Secure Sovereignty’ if Challenged by China,” GMA News Online, April