AIM: An Integrated Approach to Organizational Improvement
Directory of Open Access Journals (Sweden)
Ronald A. Styron, Jr.
2016-02-01
Full Text Available This concept paper is based on the new problem-solving model of Blended Leadership called Alloy Improvement Model (AIM. This model consists of an integration of change theory, leadership theory, and democratic principles and practices to form a comprehensive problem-solving strategy for organizational leaders. The utilization of AIM will assist leaders in moving from problems to solutions while engaging stakeholders in a comprehensive, efficient, inclusive, informative, integrated and transparent process.
Treatments of jute fibers aiming at improvement of fiber-phenolic matrix adhesion
Directory of Open Access Journals (Sweden)
Ilce Aiko Tanaka Razera
2014-08-01
Full Text Available Composites based on a thermoset phenolic matrix and jute fibers were prepared and characterized. The fibers were alternatively treated with ionized air or aqueous alkaline solution (mercerization with the aim of introducing changes in the morphology, dispersive component of surface free energy, γS D (estimated by Inverse Gas Chromatography, IGC and the acid/base character of their surfaces, shown by their ANs/DNs ratio (estimated by IGC, and their degree of crystallinity. The final objective was to investigate the influence of these modifications on the adhesion at the jute fiber/phenolic matrix interface in the composites. The untreated jute fiber showed 50% crystallinity, γS D=18 mJ m- 2 and ANs/DNs= 0.9 (amphoteric surface, tensile strength = 460 MPa and maximum elongation = 0.7%, while the respective composite had an impact strength of 72.6 J m- 1. The treatments positively modified the fibers and the adhesion at the interface was better in the composites reinforced with treated fibers than with untreated fibers. The best set of results was exhibited by the fiber treated with 10% NaOH [46% crystallinity, γS D = 26 J m- 2 (phenolic matrix γS D = 32 J m- 2, ANs/DNs = 1.8 (surface predominantly acidic, similar to phenolic matrix, ANs/DNs = 1.4, tensile strength approximately 900 MPa, maximum elongation = 2%, impact strength of respective composite approximately 95 J m- 1]. The fibers treated for 5 h with ionized air exhibited favorable properties [(45% crystallinity, γS D = 27 J m- 2, ANs/DNs = 2.1 (acidic surface] for further use as reinforcement of a phenolic matrix, but their partial degradation during the treatment decreased their tensile properties (395 MPa and 0.5% for tensile strength and maximum elongation, respectively and their action as reinforcement (impact strength of the respective composite approximately 73 J m- 1.
An integrating factor matrix method to find first integrals
International Nuclear Information System (INIS)
Saputra, K V I; Quispel, G R W; Van Veen, L
2010-01-01
In this paper we develop an integrating factor matrix method to derive conditions for the existence of first integrals. We use this novel method to obtain first integrals, along with the conditions for their existence, for two- and three-dimensional Lotka-Volterra systems with constant terms. The results are compared to previous results obtained by other methods.
Chen, Zhe; Honomichl, Ryan; Kennedy, Diane; Tan, Enda
2016-06-01
The present study examines 5- to 8-year-old children's relation reasoning in solving matrix completion tasks. This study incorporates a componential analysis, an eye-tracking method, and a microgenetic approach, which together allow an investigation of the cognitive processing strategies involved in the development and learning of children's relational thinking. Developmental differences in problem-solving performance were largely due to deficiencies in engaging the processing strategies that are hypothesized to facilitate problem-solving performance. Feedback designed to highlight the relations between objects within the matrix improved 5- and 6-year-olds' problem-solving performance, as well as their use of appropriate processing strategies. Furthermore, children who engaged the processing strategies early on in the task were more likely to solve subsequent problems in later phases. These findings suggest that encoding relations, integrating rules, completing the model, and generalizing strategies across tasks are critical processing components that underlie relational thinking. (PsycINFO Database Record (c) 2016 APA, all rights reserved).
Housing First and Social Integration: A Realistic Aim?
Directory of Open Access Journals (Sweden)
Deborah Quilgars
2016-10-01
Full Text Available Housing First is now dominating discussions about how best to respond to homelessness among people with high and complex needs throughout the EU and in several countries within the OECD. Whilst recognised internationally as an effective model in addressing homelessness, little attention has been given as to whether Housing First also assists previously homeless people become more socially integrated into their communities. This paper reviews the available research evidence (utilising a Rapid Evidence Assessment methodology on the extent to which Housing First services are effective in promoting social integration. Existing evidence suggests Housing First is delivering varying results in respect of social integration, despite some evidence suggesting normalising effects of settled housing on ontological security. The paper argues that a lack of clarity around the mechanisms by which Housing First is designed to deliver ‘social integration’, coupled with poor measurement, helps explain the inconsistent and sometimes limited results for Housing First services in this area. It concludes that there is a need to look critically at the extent to which Housing First can deliver social integration, moving the debate beyond the successes in housing sustainment and identifying what is needed to enhance people’s lives in the longer-term.
Integrated optic vector-matrix multiplier
Watts, Michael R [Albuquerque, NM
2011-09-27
A vector-matrix multiplier is disclosed which uses N different wavelengths of light that are modulated with amplitudes representing elements of an N.times.1 vector and combined to form an input wavelength-division multiplexed (WDM) light stream. The input WDM light stream is split into N streamlets from which each wavelength of the light is individually coupled out and modulated for a second time using an input signal representing elements of an M.times.N matrix, and is then coupled into an output waveguide for each streamlet to form an output WDM light stream which is detected to generate a product of the vector and matrix. The vector-matrix multiplier can be formed as an integrated optical circuit using either waveguide amplitude modulators or ring resonator amplitude modulators.
Aiming for a fully integrated computerized procedure system
International Nuclear Information System (INIS)
Marron, J. E.
2006-01-01
A fully integrated Computerized Procedure System must provide, at a minimum, a) Specification: access to design basis procedures, b) Monitoring: incorporation of real-time plant status, c) Advise: highlighting likely decision paths, and d) Reporting: logging conditions and actions taken. The CPS plays a critical role in overcoming the human factors that lead to accidents. At the same time it can be an essential tool in providing the information and automation to augment what humans do best, identify patterns and make associative leaps in the presence of ambiguous data. Timeliner and TaskGuide are examples of CPS that have evolved from projects in the aerospace industry. They illustrate certain common characteristics of a CPS, namely the knowledge base, user interface, and traceability features. The complexity and number of procedures for a current nuclear project has led to the development of two tools, the Power Generation Control System (PGCS) and the Online Procedure System (OLPS). Together, these systems address the knowledge-base and user interface aspects of a CPS and go a long way in addressing other areas. PGCS and OLPS contain full configuration management capabilities for procedures and the operating recipe. They include administrative functions for online and offline management of documents and data. Some lessons learned from this pair of programs developed by Invensys is the need for more integrated recording mechanisms. The future of CPS is likely to see higher integration of the document access, system status, decision support and logging capabilities. The CPS may evolve into the standard operational interface. Internet technologies that are common-place today have made the possibility of the Active Document a reality. The OPC Foundation is pursuing standards that may accelerate such developments. (authors)
Integrated planning aimed at sustainability city logistics solutions
Directory of Open Access Journals (Sweden)
Tadić Snežana R.
2015-01-01
Full Text Available The main objective of city logistics system is sustainability, or efficiency, wide acceptability, environmental protection and safety. On the other hand, the city logistics system is very complex. It is characterized by a large number of participants, with different, usually conflicting goals and complex interactions. In addition, the system of city logistics is part of a wider system of the town, the region, and there are complex interactions with the external environment. The system depends on the specific characteristics of the city, affects other forms of urban mobility and is subject to the policies of higher rank (regional, national policy. Given the exceptional complexity, sustainable city logistics solution requires an integrated approach in all phases of planning, from stages of problem identification, definition of alternative solutions and effects assessment, to implementation and by exploitation. In this way, the solution of city logistics is becoming widely accepted and not only affects the efficiency of the socio-economic system of town, already on the sustainability of the whole region.
Structured Matrix Completion with Applications to Genomic Data Integration.
Cai, Tianxi; Cai, T Tony; Zhang, Anru
2016-01-01
Matrix completion has attracted significant recent attention in many fields including statistics, applied mathematics and electrical engineering. Current literature on matrix completion focuses primarily on independent sampling models under which the individual observed entries are sampled independently. Motivated by applications in genomic data integration, we propose a new framework of structured matrix completion (SMC) to treat structured missingness by design. Specifically, our proposed method aims at efficient matrix recovery when a subset of the rows and columns of an approximately low-rank matrix are observed. We provide theoretical justification for the proposed SMC method and derive lower bound for the estimation errors, which together establish the optimal rate of recovery over certain classes of approximately low-rank matrices. Simulation studies show that the method performs well in finite sample under a variety of configurations. The method is applied to integrate several ovarian cancer genomic studies with different extent of genomic measurements, which enables us to construct more accurate prediction rules for ovarian cancer survival.
Constrained KP models as integrable matrix hierarchies
International Nuclear Information System (INIS)
Aratyn, H.; Ferreira, L.A.; Gomes, J.F.; Zimerman, A.H.
1997-01-01
We formulate the constrained KP hierarchy (denoted by cKP K+1,M ) as an affine [cflx sl](M+K+1) matrix integrable hierarchy generalizing the Drinfeld endash Sokolov hierarchy. Using an algebraic approach, including the graded structure of the generalized Drinfeld endash Sokolov hierarchy, we are able to find several new universal results valid for the cKP hierarchy. In particular, our method yields a closed expression for the second bracket obtained through Dirac reduction of any untwisted affine Kac endash Moody current algebra. An explicit example is given for the case [cflx sl](M+K+1), for which a closed expression for the general recursion operator is also obtained. We show how isospectral flows are characterized and grouped according to the semisimple non-regular element E of sl(M+K+1) and the content of the center of the kernel of E. copyright 1997 American Institute of Physics
Towards integrating extracellular matrix and immunological pathways.
Boyd, David F; Thomas, Paul G
2017-10-01
The extracellular matrix (ECM) is a complex and dynamic structure made up of an estimated 300 different proteins. The ECM is also a rich source of cytokines and growth factors in addition to numerous bioactive ECM degradation products that influence cell migration, proliferation, and differentiation. The ECM is constantly being remodeled during homeostasis and in a wide range of pathological contexts. Changes in the ECM modulate immune responses, which in turn regulate repair and regeneration of tissues. Here, we review the many components of the ECM, enzymes involved in ECM remodeling, and the signals that feed into immunological pathways in the context of a dynamic ECM. We highlight studies that have taken an integrative approach to studying immune responses in the context of the ECM and studies that use novel proteomic strategies. Finally, we discuss research challenges relevant to the integration of immune and ECM networks and propose experimental and translational approaches to resolve these issues. Copyright © 2017 Elsevier Ltd. All rights reserved.
National Research Council Canada - National Science Library
Baker, Kevin; Youngson, Gord
2007-01-01
To enhance the capability of airborne search and rescue (SAR) and surveillance, particularly at night and in poor weather, a multi sensor electro optical imaging system, the Advanced Integrated Multi sensor Surveillance (AIMS...
Integrating Molecular Computation and Material Production in an Artificial Subcellular Matrix
DEFF Research Database (Denmark)
Fellermann, Harold; Hadorn, Maik; Bönzli, Eva
Living systems are unique in that they integrate molecular recognition and information processing with material production on the molecular scale. Pre- dominant locus of this integration is the cellular matrix, where a multitude of biochemical reactions proceed simultaneously in highly compartmen......Living systems are unique in that they integrate molecular recognition and information processing with material production on the molecular scale. Pre- dominant locus of this integration is the cellular matrix, where a multitude of biochemical reactions proceed simultaneously in highly...... compartmentalized re- action compartments that interact and get delivered through vesicle trafficking. The European Commission funded project MatchIT (Matrix for Chemical IT) aims at creating an artificial cellular matrix that seamlessly integrates infor- mation processing and material production in much the same...
N=2 3d-matrix integral with Myers term
International Nuclear Information System (INIS)
Tomino, Dan
2004-01-01
An exact matrix integral is evaluated for a 2x2 3-dimensional matrix model with Myers term. We derive weak and strong coupling expansions of the effective action. We also calculate the expectation values of the quadratic and cubic operators. Implications for non-commutative gauge theory on fuzzy sphere are discussed. (author)
Integration of concepts: cardiac extracellular matrix remodeling after myocardial infarction
Cleutjens, Jack P. M.; Creemers, Esther E. J. M.
2002-01-01
The cardiac extracellular matrix consists of a three-dimensional structural network of interstitial collagens to which other matrix components are attached. The main physiological functions of this network are to retain tissue integrity and cardiac pump function. Collagen deposition is controlled
The Ambulatory Integration of the Medical and Social (AIMS) model: A retrospective evaluation.
Rowe, Jeannine M; Rizzo, Victoria M; Shier Kricke, Gayle; Krajci, Kate; Rodriguez-Morales, Grisel; Newman, Michelle; Golden, Robyn
2016-01-01
An exploratory, retrospective evaluation of Ambulatory Integration of the Medical and Social (AIMS), a care coordination model designed to integrate medical and non-medical needs of patients and delivered exclusively by social workers was conducted to examine mean utilization of costly health care services for older adult patients. Results reveal mean utilization of 30-day hospital readmissions, emergency department (ED) visits, and hospital admissions are significantly lower for the study sample compared to the larger patient population. Comparisons with national population statistics reveal significantly lower mean utilization of 30-day admissions and ED visits for the study sample. The findings offer preliminary support regarding the value of AIMS.
RE-AIM Checklist for Integrating and Sustaining Tier 2 Social-Behavioral Interventions
Cheney, Douglas A.; Yong, Minglee
2014-01-01
Even though evidence-based Tier 2 programs are now more commonly available, integrating and sustaining these interventions in schools remain challenging. RE-AIM, which stands for Reach, Effectiveness, Adoption, Implementation, and Maintenance, is a public health framework used to maximize the effectiveness of health promotion programs in…
Integrable Floquet dynamics, generalized exclusion processes and "fused" matrix ansatz
Vanicat, Matthieu
2018-04-01
We present a general method for constructing integrable stochastic processes, with two-step discrete time Floquet dynamics, from the transfer matrix formalism. The models can be interpreted as a discrete time parallel update. The method can be applied for both periodic and open boundary conditions. We also show how the stationary distribution can be built as a matrix product state. As an illustration we construct parallel discrete time dynamics associated with the R-matrix of the SSEP and of the ASEP, and provide the associated stationary distributions in a matrix product form. We use this general framework to introduce new integrable generalized exclusion processes, where a fixed number of particles is allowed on each lattice site in opposition to the (single particle) exclusion process models. They are constructed using the fusion procedure of R-matrices (and K-matrices for open boundary conditions) for the SSEP and ASEP. We develop a new method, that we named "fused" matrix ansatz, to build explicitly the stationary distribution in a matrix product form. We use this algebraic structure to compute physical observables such as the correlation functions and the mean particle current.
Non-Abelian integrable hierarchies: matrix biorthogonal polynomials and perturbations
Ariznabarreta, Gerardo; García-Ardila, Juan C.; Mañas, Manuel; Marcellán, Francisco
2018-05-01
In this paper, Geronimus–Uvarov perturbations for matrix orthogonal polynomials on the real line are studied and then applied to the analysis of non-Abelian integrable hierarchies. The orthogonality is understood in full generality, i.e. in terms of a nondegenerate continuous sesquilinear form, determined by a quasidefinite matrix of bivariate generalized functions with a well-defined support. We derive Christoffel-type formulas that give the perturbed matrix biorthogonal polynomials and their norms in terms of the original ones. The keystone for this finding is the Gauss–Borel factorization of the Gram matrix. Geronimus–Uvarov transformations are considered in the context of the 2D non-Abelian Toda lattice and noncommutative KP hierarchies. The interplay between transformations and integrable flows is discussed. Miwa shifts, τ-ratio matrix functions and Sato formulas are given. Bilinear identities, involving Geronimus–Uvarov transformations, first for the Baker functions, then secondly for the biorthogonal polynomials and its second kind functions, and finally for the τ-ratio matrix functions, are found.
Directory of Open Access Journals (Sweden)
Gertrud Pfister
2013-12-01
Full Text Available The aim of this article is to introduce a new research topic and provide information about a European research project focusing on football as a means of European integration. Using the results of available studies of the author and other scholars, it is to be discussed whether and how women can participate in football cultures and contribute to a European identity. Based on theoretical approaches to national identity, gender and socialization, as well as and on the analysis of various intersections between gender, football and fandom, it can be concluded that women are still outsiders in the world of football and that it is doubtful whether female players and fans will contribute decisively to Europeanization processes.
Advanced emission control system: CO2 sequestration using algae integrated management system (AIMS)
International Nuclear Information System (INIS)
Syed Isa Syed Alwi; Mohd Norsham Che Yahya; Ruzanna Abdul Rahman
2010-01-01
One of the companies under Algae tech, Sasaran Bio fuel Sdn. Bhd. provides project management, technology transfer and technical expertise to develop a solution to minimize and mitigate Carbon Dioxide (CO 2 ) emissions through the diversion of the CO 2 to open algal ponds and enclosed photo-bioreactors as algal propagation technologies to consume CO 2 waste stream. The company is presently consulting a listed company from Indonesia to address the technology know-how and implementation of microalgae development from the flue gas of the Groups power plants. Nowadays, one of the aspects that contribute to the air pollution is the emission of flue gases from the factories. So, we provide a system that can reduce the emission of flue gas to the atmosphere and at the same time, cultivate certain strain of algae. With the technology, Algae Integrated Management System (AIMS), it will be for sure a new beginning for way to reduce air pollution. The utilization of power plant resources for growing selected microalgae at a low energy cost for valuable products and bio-fuels while providing CO 2 sequestering. In the same time, it also a low cost algae agriculture. By doing so, it provides all year algae production which can be an income. This residual energy used CO 2 produced from power stations and industrial plants to feed the process (CO 2 recycling and bio-fixation) in cultivation of algae. This will be a low cost flue gas (CO 2 ) to the developer. In a nutshell, CO 2 Sequestration by algae reactors is a potential to reduce greenhouse gas emission by using the CO 2 in the stack gases to produce algae. (author)
Gordeev, S. I.; Bogatova, T. F.; Ryzhkov, A. F.
2017-11-01
Raising the efficiency and environmental friendliness of electric power generation from coal is the aim of numerous research groups today. The traditional approach based on the steam power cycle has reached its efficiency limit, prompted by materials development and maneuverability performance. The rival approach based on the combined cycle is also drawing nearer to its efficiency limit. However, there is a reserve for efficiency increase of the integrated gasification combined cycle, which has the energy efficiency at the level of modern steam-turbine power units. The limit of increase in efficiency is the efficiency of NGCC. One of the main problems of the IGCC is higher costs of receiving and preparing fuel gas for GTU. It would be reasonable to decrease the necessary amount of fuel gas in the power unit to minimize the costs. The effect can be reached by raising of the heat value of fuel gas, its heat content and the heat content of cycle air. On the example of the process flowsheet of the IGCC with a power of 500 MW, running on Kuznetsk bituminous coal, by means of software Thermoflex, the influence of the developed technical solutions on the efficiency of the power plant is considered. It is received that rise in steam-air blast temperature to 900°C leads to an increase in conversion efficiency up to 84.2%. An increase in temperature levels of fuel gas clean-up to 900°C leads to an increase in the IGCC efficiency gross/net by 3.42%. Cycle air heating reduces the need for fuel gas by 40% and raises the IGCC efficiency gross/net by 0.85-1.22%. The offered solutions for IGCC allow to exceed net efficiency of analogous plants by 1.8-2.3%.
Integrated assessment of biodiesel policies aimed at family farms in Brazil
Belo Leite, Dal J.G.; Nunes Vieira da Silva, J.V.; Ittersum, van M.K.
2014-01-01
With many of the poor people in Brazil living in rural areas, local governments have intensified their efforts to design and implement effective policies that boost rural development. In 2004, a national program for production and use of biodiesel was launched aiming at increasing income among less
One model to fit all? The pursuit of integrated earth system models in GAIM and AIMES
Uhrqvist, Ola
2015-01-01
Images of Earth from space popularized the view of our planet as a single, fragile entity against the vastness and darkness of space. In the 1980s, the International Geosphere-Biosphere Program (IGBP) was set up to produce a predictive understanding of this fragile entity as the ‘Earth System.’ In order to do so, the program sought to create a common research framework for the different disciplines involved. It suggested that integrated numerical models could provide such a framework. The pap...
Poling of PVDF matrix composites for integrated structural load sensing
Haghiashtiani, Ghazaleh; Greminger, Michael A.; Zhao, Ping
2014-03-01
The purpose of this study is to create and evaluate a smart composite structure that can be used for integrated load sensing and structural health monitoring. In this structure, PVDF films are used as the matrix material instead of epoxy resin or other thermoplastics. The reinforcements are two layers of carbon fiber with one layer of Kevlar separating them. Due to the electrical conductivity properties of carbon fiber and the dielectric effect of Kevlar, the structure acts as a capacitor. Furthermore, the piezoelectric properties of the PVDF matrix can be used to monitor the response of the structure under applied loads. In order to exploit the piezoelectric properties of PVDF, the PVDF material must be polarized to align the dipole moments of its crystalline structure. The optimal condition for poling the structure was found by performing a 23 factorial design of experiment (DoE). The factors that were studied in DoE were temperature, voltage, and duration of poling. Finally, the response of the poled structure was monitored by exposing the samples to an applied load.
Yoon, Junghyo; Korkmaz Zirpel, Nuriye; Park, Hyun-Ji; Han, Sewoon; Hwang, Kyung Hoon; Shin, Jisoo; Cho, Seung-Woo; Nam, Chang-Hoon; Chung, Seok
2016-01-21
Here, a growth-factor-integrated natural extracellular matrix of type I collagen is presented that induces angiogenesis. The developed matrix adapts type I collagen nanofibers integrated with synthetic colloidal particles of recombinant bacteriophages that display vascular endothelial growth factor (VEGF). The integration is achieved during or after gelation of the type I collagen and the matrix enables spatial delivery of VEGF into a desired region. Endothelial cells that contact the VEGF are found to invade into the matrix to form tube-like structures both in vitro and in vivo, proving the angiogenic potential of the matrix. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Molten carbonate fuel cell integral matrix tape and bubble barrier
International Nuclear Information System (INIS)
Reiser, C.A.; Maricle, D.L.
1983-01-01
A molten carbonate fuel cell matrix material is described made up of a matrix tape portion and a bubble barrier portion. The matrix tape portion comprises particles inert to molten carbonate electrolyte, ceramic particles and a polymeric binder, the matrix tape being flexible, pliable and having rubber-like compliance at room temperature. The bubble barrier is a solid material having fine porosity preferably being bonded to the matrix tape. In operation in a fuel cell, the polymer binder burns off leaving the matrix and bubble barrier providing superior sealing, stability and performance properties to the fuel cell stack
Leslie, R Scott; Tirado, Breanne; Patel, Bimal V; Rein, Philip J
2014-12-01
star to 2 stars for HTN), which contributed to increases in the Drug Plan Quality Improvement measure (2 stars to 4 stars) and iCare's overall Part D star rating (3 to 3.5 stars). Members in this MA-PD plan dual-eligible population benefited from multiple points of contact to achieve increased adherence. Health plans can use network pharmacies, care management staff, and their pharmacy benefits managers to collaborate and implement interventions aimed to improve members' adherence to targeted maintenance medications and overall health plan quality performance and star ratings.
Improved parallel solution techniques for the integral transport matrix method
Energy Technology Data Exchange (ETDEWEB)
Zerr, R. Joseph, E-mail: rjz116@psu.edu [Department of Mechanical and Nuclear Engineering, The Pennsylvania State University, University Park, PA (United States); Azmy, Yousry Y., E-mail: yyazmy@ncsu.edu [Department of Nuclear Engineering, North Carolina State University, Burlington Engineering Laboratories, Raleigh, NC (United States)
2011-07-01
Alternative solution strategies to the parallel block Jacobi (PBJ) method for the solution of the global problem with the integral transport matrix method operators have been designed and tested. The most straightforward improvement to the Jacobi iterative method is the Gauss-Seidel alternative. The parallel red-black Gauss-Seidel (PGS) algorithm can improve on the number of iterations and reduce work per iteration by applying an alternating red-black color-set to the subdomains and assigning multiple sub-domains per processor. A parallel GMRES(m) method was implemented as an alternative to stationary iterations. Computational results show that the PGS method can improve on the PBJ method execution time by up to 10´ when eight sub-domains per processor are used. However, compared to traditional source iterations with diffusion synthetic acceleration, it is still approximately an order of magnitude slower. The best-performing cases are optically thick because sub-domains decouple, yielding faster convergence. Further tests revealed that 64 sub-domains per processor was the best performing level of sub-domain division. An acceleration technique that improves the convergence rate would greatly improve the ITMM. The GMRES(m) method with a diagonal block pre conditioner consumes approximately the same time as the PBJ solver but could be improved by an as yet undeveloped, more efficient pre conditioner. (author)
Improved parallel solution techniques for the integral transport matrix method
International Nuclear Information System (INIS)
Zerr, R. Joseph; Azmy, Yousry Y.
2011-01-01
Alternative solution strategies to the parallel block Jacobi (PBJ) method for the solution of the global problem with the integral transport matrix method operators have been designed and tested. The most straightforward improvement to the Jacobi iterative method is the Gauss-Seidel alternative. The parallel red-black Gauss-Seidel (PGS) algorithm can improve on the number of iterations and reduce work per iteration by applying an alternating red-black color-set to the subdomains and assigning multiple sub-domains per processor. A parallel GMRES(m) method was implemented as an alternative to stationary iterations. Computational results show that the PGS method can improve on the PBJ method execution time by up to 10´ when eight sub-domains per processor are used. However, compared to traditional source iterations with diffusion synthetic acceleration, it is still approximately an order of magnitude slower. The best-performing cases are optically thick because sub-domains decouple, yielding faster convergence. Further tests revealed that 64 sub-domains per processor was the best performing level of sub-domain division. An acceleration technique that improves the convergence rate would greatly improve the ITMM. The GMRES(m) method with a diagonal block pre conditioner consumes approximately the same time as the PBJ solver but could be improved by an as yet undeveloped, more efficient pre conditioner. (author)
Some open problems in random matrix theory and the theory of integrable systems
Deift, Percy
2007-01-01
We describe a list of open problems in random matrix theory and integrable systems which was presented at the conference ``Integrable Systems, Random Matrices, and Applications'' at the Courant Institute in May 2006.
Bisetti, Fabrizio
2012-01-01
with the computational cost associated with the time integration of stiff, large chemical systems, a novel approach is proposed. The approach combines an exponential integrator and Krylov subspace approximations to the exponential function of the Jacobian matrix
Symmetries of integrable hierarchies and matrix model constraints
International Nuclear Information System (INIS)
Vos, K. de
1992-01-01
The orbit construction associates a soliton hierarchy to every level-one vertex realization of a simply laced affine Kac-Moody algebra g. We show that the τ-function of such a hierarchy has the (truncated) Virasoro algebra as an algebra of infinitesimal symmetry transformations. To prove this we use an appropriate bilinear form of these hierarchies together with the coset construction of conformal field theory. For A 1 (1) the orbit construction gives either the Toda or the KdV hierarchy. These both occur in the one-matrix model of two-dimensional quantum gravity, before and after the double scaling limit respectively. The truncated Virasoro symmetry algebra is exactly the algebra of constraints of the one-matrix model. The partition function of the one-matrix model is therefore an invariant τ-function. We also consider the case of A 1 (1) with l>1. Surprisingly, the symmetry algebra in that case is not simply a truncated Casimir algebra. It appears that again only the Virasoro symmetry survives. We speculate on the relation with multi-matrix models. (orig.)
Form factors in quantum integrable models with GL(3)-invariant R-matrix
Energy Technology Data Exchange (ETDEWEB)
Pakuliak, S., E-mail: pakuliak@theor.jinr.ru [Laboratory of Theoretical Physics, JINR, 141980 Dubna, Moscow Reg. (Russian Federation); Moscow Institute of Physics and Technology, 141700 Dolgoprudny, Moscow Reg. (Russian Federation); Institute of Theoretical and Experimental Physics, 117259 Moscow (Russian Federation); Ragoucy, E., E-mail: eric.ragoucy@lapth.cnrs.fr [Laboratoire de Physique Théorique LAPTH, CNRS and Université de Savoie, BP 110, 74941 Annecy-le-Vieux Cedex (France); Slavnov, N.A., E-mail: nslavnov@mi.ras.ru [Steklov Mathematical Institute, Moscow (Russian Federation)
2014-04-15
We study integrable models solvable by the nested algebraic Bethe ansatz and possessing GL(3)-invariant R-matrix. We obtain determinant representations for form factors of off-diagonal entries of the monodromy matrix. These representations can be used for the calculation of form factors and correlation functions of the XXX SU(3)-invariant Heisenberg chain.
Data Entities and Information System Matrix for Integrated Agriculture Information System (IAIS)
Budi Santoso, Halim; Delima, Rosa
2018-03-01
Integrated Agriculture Information System is a system that is developed to process data, information, and knowledge in Agriculture sector. Integrated Agriculture Information System brings valuable information for farmers: (1) Fertilizer price; (2) Agriculture technique and practise; (3) Pest management; (4) Cultivation; (5) Irrigation; (6) Post harvest processing; (7) Innovation in agriculture processing. Integrated Agriculture Information System contains 9 subsystems. To bring an integrated information to the user and stakeholder, it needs an integrated database approach. Thus, researchers describes data entity and its matrix relate to subsystem in Integrated Agriculture Information System (IAIS). As a result, there are 47 data entities as entities in single and integrated database.
Lown, Beth A; McIntosh, Sharrie; Gaines, Martha E; McGuinn, Kathy; Hatem, David S
2016-03-01
Empathy and compassion provide an important foundation for effective collaboration in health care. Compassion (the recognition of and response to the distress and suffering of others) should be consistently offered by health care professionals to patients, families, staff, and one another. However, compassion without collaboration may result in uncoordinated care, while collaboration without compassion may result in technically correct but depersonalized care that fails to meet the unique emotional and psychosocial needs of all involved. Providing compassionate, collaborative care (CCC) is critical to achieving the "triple aim" of improving patients' health and experiences of care while reducing costs. Yet, values and skills related to CCC (or the "Triple C") are not routinely taught, modeled, and assessed across the continuum of learning and practice. To change this paradigm, an interprofessional group of experts recently recommended approaches and a framework for integrating CCC into health professional education and postgraduate training as well as clinical care. In this Perspective, the authors describe how the Triple C framework can be integrated and enhance existing competency standards to advance CCC across the learning and practice continuum. They also discuss strategies for partnering with patients and families to improve health professional education and health care design and delivery through quality improvement projects. They emphasize that compassion and collaboration are important sources of professional, patient, and family satisfaction as well as critical aspects of professionalism and person-centered, relationship-based high-quality care.
Killian, C. E.; Wilt, F. H.
1996-01-01
In the present study, we enumerate and characterize the proteins that comprise the integral spicule matrix of the Strongylocentrotus purpuratus embryo. Two-dimensional gel electrophoresis of [35S]methionine radiolabeled spicule matrix proteins reveals that there are 12 strongly radiolabeled spicule matrix proteins and approximately three dozen less strongly radiolabeled spicule matrix proteins. The majority of the proteins have acidic isoelectric points; however, there are several spicule matrix proteins that have more alkaline isoelectric points. Western blotting analysis indicates that SM50 is the spicule matrix protein with the most alkaline isoelectric point. In addition, two distinct SM30 proteins are identified in embryonic spicules, and they have apparent molecular masses of approximately 43 and 46 kDa. Comparisons between embryonic spicule matrix proteins and adult spine integral matrix proteins suggest that the embryonic 43-kDa SM30 protein is an embryonic isoform of SM30. An adult 49-kDa spine matrix protein is also identified as a possible adult isoform of SM30. Analysis of the SM30 amino acid sequences indicates that a portion of SM30 proteins is very similar to the carbohydrate recognition domain of C-type lectin proteins.
Addressable Inverter Matrix Tests Integrated-Circuit Wafer
Buehler, Martin G.
1988-01-01
Addressing elements indirectly through shift register reduces number of test probes. With aid of new technique, complex test structure on silicon wafer tested with relatively small number of test probes. Conserves silicon area by reduction of area devoted to pads. Allows thorough evaluation of test structure characteristics and of manufacturing process parameters. Test structure consists of shift register and matrix of inverter/transmission-gate cells connected to two-by-ten array of probe pads. Entire pattern contained in square area having only 1.6-millimeter sides. Shift register is conventional static CMOS device using inverters and transmission gates in master/slave D flip-flop configuration.
Addressable-Matrix Integrated-Circuit Test Structure
Sayah, Hoshyar R.; Buehler, Martin G.
1991-01-01
Method of quality control based on use of row- and column-addressable test structure speeds collection of data on widths of resistor lines and coverage of steps in integrated circuits. By use of straightforward mathematical model, line widths and step coverages deduced from measurements of electrical resistances in each of various combinations of lines, steps, and bridges addressable in test structure. Intended for use in evaluating processes and equipment used in manufacture of application-specific integrated circuits.
Direct integration of the S-matrix applied to rigorous diffraction
International Nuclear Information System (INIS)
Iff, W; Lindlein, N; Tishchenko, A V
2014-01-01
A novel Fourier method for rigorous diffraction computation at periodic structures is presented. The procedure is based on a differential equation for the S-matrix, which allows direct integration of the S-matrix blocks. This results in a new method in Fourier space, which can be considered as a numerically stable and well-parallelizable alternative to the conventional differential method based on T-matrix integration and subsequent conversions from the T-matrices to S-matrix blocks. Integration of the novel differential equation in implicit manner is expounded. The applicability of the new method is shown on the basis of 1D periodic structures. It is clear however, that the new technique can also be applied to arbitrary 2D periodic or periodized structures. The complexity of the new method is O(N 3 ) similar to the conventional differential method with N being the number of diffraction orders. (fast track communication)
Matrix integral solutions to the discrete KP hierarchy and its Pfaffianized version
International Nuclear Information System (INIS)
Lafortune, Stéphane; Li, Chun-Xia
2016-01-01
Matrix integrals used in random matrix theory for the study of eigenvalues of Hermitian ensembles have been shown to provide τ -functions for several hierarchies of integrable equations. In this article, we extend this relation by showing that such integrals can also provide τ -functions for the discrete KP hierarchy and a coupled version of the same hierarchy obtained through the process of Pfaffianization. To do so, we consider the first equation of the discrete KP hierarchy, the Hirota–Miwa equation. We write the Wronskian determinant solutions to the Hirota–Miwa equation and consider a particular form of matrix integrals, which we show is an example of those Wronskian solutions. The argument is then generalized to the whole hierarchy. A similar strategy is used for the Pfaffianized version of the hierarchy except that in that case, the solutions are written in terms of Pfaffians rather than determinants. (paper)
On calculation of zeta function of integral matrix
Czech Academy of Sciences Publication Activity Database
Janáček, Jiří
2009-01-01
Roč. 134, č. 1 (2009), s. 49-58 ISSN 0862-7959 R&D Projects: GA AV ČR(CZ) IAA100110502 Institutional research plan: CEZ:AV0Z50110509 Keywords : Epstein zeta function * integral lattice * Riemann theta function Subject RIV: BA - General Mathematics
Introduction to path integrals, matrix models and strings
International Nuclear Information System (INIS)
Jevicki, A.
1995-01-01
The major strength of the theory is then that it is integrable and exactly solvable. Its integrable nature leads to understanding of a w ∞ algebra as a space-time symmetry of string theory. This algebra acts in a nonlinear way on the basic collective field representing a massless tachyon. It is interpreted as a spectrum-generating algebra allowing to build an infinite sequence of discrete imaginary energy states which turn out to be remnants of higher string modes in two dimensions. The presence and interplay of discrete modes with the scalar tachyon are particularly interesting. The w ∞ symmetry is seen to serve as an organizational principle and is of much broader relevance. (orig.)
Bickford, Justin; Guicheteau, Jason
2016-05-01
Integrated photonics affords an opportunity to explore novel sensing and lab-on-a-chip concepts. It offers a route to high sensitivity, high selectivity, and low SWaP-C test systems that can be operated autonomously or by minimallytrained field personnel. We'll introduce the topic, discuss possible sensing modalities, and highlight the advantages and limitations of this technology. We'll also introduce the recent American Institute for Manufacturing Integrated Photonics (AIM Photonics), give an overview of its vision and capabilities, how to utilize its Electronic-Photonic Design Automation (EPDA) tools and its Multi-Project Wafer and Assembly (MPWA) services, how to engage in its road mapping efforts, and how to become a contributing member.
Structure of collagen-glycosaminoglycan matrix and the influence to its integrity and stability.
Bi, Yuying; Patra, Prabir; Faezipour, Miad
2014-01-01
Glycosaminoglycan (GAG) is a chain-like disaccharide that is linked to polypeptide core to connect two collagen fibrils/fibers and provide the intermolecular force in Collagen-GAG matrix (C-G matrix). Thus, the distribution of GAG in C-G matrix contributes to the integrity and mechanical properties of the matrix and related tissue. This paper analyzes the transverse isotropic distribution of GAG in C-G matrix. The angle of GAGs related to collagen fibrils is used as parameters to qualify the GAGs isotropic characteristic in both 3D and 2D rendering. Statistical results included that over one third of GAGs were perpendicular directed to collagen fibril with symmetrical distribution for both 3D matrix and 2D plane cross through collagen fibrils. The three factors tested in this paper: collagen radius, collagen distribution, and GAGs density, were not statistically significant for the strength of Collagen-GAG matrix in 3D rendering. However in 2D rendering, a significant factor found was the radius of collagen in matrix for the GAGs directed to orthogonal plane of Collagen-GAG matrix. Between two cross-section selected from Collagen-GAG matrix model, the plane cross through collagen fibrils was symmetrically distributed but the total percentage of perpendicular directed GAG was deducted by decreasing collagen radius. There were some symmetry features of GAGs angle distribution in selected 2D plane that passed through space between collagen fibrils, but most models showed multiple peaks in GAGs angle distribution. With less GAGs directed to perpendicular of collagen fibril, strength in collagen cross-section weakened. Collagen distribution was also a factor that influences GAGs angle distribution in 2D rendering. True hexagonal collagen packaging is reported in this paper to have less strength at collagen cross-section compared to quasi-hexagonal collagen arrangement. In this work focus is on GAGs matrix within the collagen and its relevance to anisotropy.
Gaede, A. E.; Platte, W. (Editor)
1975-01-01
The data reduction program used to analyze the performance of the Aerothermodynamic Integration Model is described. Routines to acquire, calibrate, and interpolate the test data, to calculate the axial components of the pressure area integrals and the skin function coefficients, and to report the raw data in engineering units are included along with routines to calculate flow conditions in the wind tunnel, inlet, combustor, and nozzle, and the overall engine performance. Various subroutines were modified and used to obtain species concentrations and transport properties in chemical equilibrium at each of the internal and external engine stations. It is recommended that future test plans include the configuration, calibration, and channel assignment data on a magnetic tape generated at the test site immediately before or after a test, and that the data reduction program be designed to operate in a batch environment.
Freire, Kimberley E.; Zakocs, Ronda; Le, Brenda; Hill, Jessica A.; Brown, Pamela; Wheaton, Jocelyn
2018-01-01
Background Intimate partner violence (IPV) has been recognized as a public health problem since the late 20th century. To spur IPV prevention efforts nationwide, the DELTA PREP Project selected 19 state domestic violence coalitions to build organizational prevention capacity and catalyze IPV primary prevention strategies within their states. Objective DELTA PREP’s summative evaluation addressed four major questions: (1) Did coalitions improve their prevention capacity during the project period? (2) Did coalitions serve as catalysts for prevention activities within their states during the project period? (3) Was initial prevention capacity associated with the number of prevention activity types initiated by coalitions by the end of the project? (4) Did coalitions sustain their prevention activities 6 months after the end of the project period? Results DELTA PREP achieved its capacity-building goal, with all 19 participant coalitions integrating prevention within their organizations and serving as catalysts for prevention activities in their states. At 6 months follow up, coalitions had sustained almost all prevention activities they initiated during the project. Baseline prevention capacity (Beginner vs. Intermediate) was not associated with the number of prevention activity types coalitions implemented by the end of the project. Conclusion Service and treatment organizations are increasingly asked to integrate a full spectrum of prevention strategies. Selecting organizations that have high levels of general capacity and readiness for an innovation like integrating a public health approach to IPV prevention will likely increase success in building an innovation-specific capacity, and in turn implementing an innovation. PMID:26245932
A new path-integral representation of the T-matrix in potential scattering
International Nuclear Information System (INIS)
Carron, J.; Rosenfelder, R.
2011-01-01
We employ the method used by Barbashov and collaborators in Quantum Field Theory to derive a path-integral representation of the T-matrix in nonrelativistic potential scattering which is free of functional integration over fictitious variables as was necessary before. The resulting expression serves as a starting point for a variational approximation applied to high-energy scattering from a Gaussian potential. Good agreement with exact partial-wave calculations is found even at large scattering angles. A novel path-integral representation of the scattering length is obtained in the low-energy limit. -- Highlights: → We derive a new path-integral representation for the T-matrix in quantum scattering from a potential. → The method is based on a technique used by Barbashov and collaborators in Quantum Field Theory. → Unlike previous approaches no unphysical degrees of freedom in the path integral are needed. → The new representation is used for a variational approximation of the T-matrix at high energies. → A new expression for the scattering length at low energy is derived.
Simplified expressions of the T-matrix integrals for electromagnetic scattering.
Somerville, Walter R C; Auguié, Baptiste; Le Ru, Eric C
2011-09-01
The extended boundary condition method, also called the null-field method, provides a semianalytic solution to the problem of electromagnetic scattering by a particle by constructing a transition matrix (T-matrix) that links the scattered field to the incident field. This approach requires the computation of specific integrals over the particle surface, which are typically evaluated numerically. We introduce here a new set of simplified expressions for these integrals in the commonly studied case of axisymmetric particles. Simplifications are obtained using the differentiation properties of the radial functions (spherical Bessel) and angular functions (associated Legendre functions) and integrations by parts. The resulting simplified expressions not only lead to faster computations, but also reduce the risks of loss of precision and provide a simpler framework for further analytical work.
Random matrix theory and higher genus integrability: the quantum chiral Potts model
International Nuclear Information System (INIS)
Angles d'Auriac, J.Ch.; Maillard, J.M.; Viallet, C.M.
2002-01-01
We perform a random matrix theory (RMT) analysis of the quantum four-state chiral Potts chain for different sizes of the chain up to size L 8. Our analysis gives clear evidence of a Gaussian orthogonal ensemble (GOE) statistics, suggesting the existence of a generalized time-reversal invariance. Furthermore, a change from the (generic) GOE distribution to a Poisson distribution occurs when the integrability conditions are met. The chiral Potts model is known to correspond to a (star-triangle) integrability associated with curves of genus higher than zero or one. Therefore, the RMT analysis can also be seen as a detector of 'higher genus integrability'. (author)
De Wever, Bart; Fuchs, Horst W; Gaca, Marianna; Krul, Cyrille; Mikulowski, Stan; Poth, Albrecht; Roggen, Erwin L; Vilà, Maya R
2012-04-01
At the IVTIP (in vitro testing industrial platform) meeting of November 26th 2009 entitled 'Toxicology in the 21st century ('21C')--working our way towards a visionary reality' all delegates endorsed the emerging concept of the '21C' vision as the way forward to enable a thorough, reliable and systematic approach to future toxicity testing without the use of animals. One of the emerging concepts focused on integrating a defined number of tests modelling in vivo-relevant and well-characterised toxicity pathways representing mechanistic endpoints. At this meeting the importance of Integrated Testing Strategies (ITS) as tools towards reduction and eventually replacement of the animals currently used for hazard identification and risk assessment was recognised. A follow-up IVTIP Spring 2010 meeting entitled 'Integrated In Vitro Testing Strategies (ITS)--Implementation Challenges' was organised to address pending questions about ITS. This report is not a review of the ITS literature, but a summary of the discussions triggered by presented examples on how to develop and implement ITS. Contrasts between pharmaceutical and chemical industry, as well as a list of general but practical aspects to be considered while developing an ITS emerged from the discussions. In addition, current recommendations on the validation of ITS were discussed. In conclusion, the outcome of this workshop improved the understanding of the participants of some important factors that may impact the design of an ITS in function of its purpose (e.g., screening, or early decision making versus regulatory), the context in which they need to be applied (e.g., ICH guidelines, REACH) and the status and quality of the available tools. A set of recommendations of best practices was established and the importance of the applicability of the individual tests as well as the testing strategy itself was highlighted. Copyright Â© 2012 Elsevier Ltd. All rights reserved.
International Nuclear Information System (INIS)
Komura, Ichiro; Hirasawa, Taiji; Nagai, Satoshi; Naruse, Katsuhiko
2002-01-01
On nuclear power plants sharing an important role in Japanese energy policy, their higher safety and reliability than the other plants are required, and their non-destructive inspection occupies important position for information means to judge their integrity. And, for a part of responses to recent rationalization of the plant operation and increase of aged plants, requirements and positioning onto the non-destructive inspection technology also change. As a result, not only concept on allowable fault sizes is adopted, but also inspection on reactor internals without conventional regulation is obliged to require for size evaluation (sizing) with higher precision to use for secure detection and integrity evaluation of the faults than sizes determined for every internals. For requirement with such higher levels for fault detection and sizing, and for requirement for effective inspection, phased-array supersonic wave fault inspection method is one of the methods with high potential power. Here were introduced on principles and characteristics of the phased-array supersonic wave fault inspection method, and on various fault inspection methods and functions mainly developed for reactor internals inspection. (G.K.)
Planar plane-wave matrix theory at the four loop order: integrability without BMN scaling
International Nuclear Information System (INIS)
Fischbacher, Thomas; Klose, Thomas; Plefka, Jan
2005-01-01
We study SU(N) plane-wave matrix theory up to fourth perturbative order in its large N planar limit. The effective hamiltonian in the closed su(2) subsector of the model is explicitly computed through a specially tailored computer program to perform large scale distributed symbolic algebra and generation of planar graphs. The number of graphs here was in the deep billions. The outcome of our computation establishes the four-loop integrability of the planar plane-wave matrix model. To elucidate the integrable structure we apply the recent technology of the perturbative asymptotic Bethe ansatz to our model. The resulting S-matrix turns out to be structurally similar but nevertheless distinct to the so far considered long-range spin-chain S-matrices of Inozemtsev, Beisert-Dippel-Staudacher and Arutyunov-Frolov-Staudacher in the AdS/CFT context. In particular our result displays a breakdown of BMN scaling at the four-loop order. That is, while there exists an appropriate identification of the matrix theory mass parameter with the coupling constant of the N=4 superconformal Yang-Mills theory which yields an eighth order lattice derivative for well separated impurities (naively implying BMN scaling) the detailed impurity contact interactions ruin this scaling property at the four-loop order. Moreover we study the issue of 'wrapping' interactions, which show up for the first time at this loop-order through a Konishi descendant length four operator. (author)
Matrix transformation relation for the radial integrals of lepton scattering processes
International Nuclear Information System (INIS)
Sud, K.K.; Soto Vargas, C.W.; Sharma, D.K.
1988-01-01
The radial integrals of many physical problems involving products of initial- and final-state wave functions and the Coulomb interaction are expressible in terms of special cases of generalized hypergeometric functions. In the present work, the generalized hypergeometric functions become elements of a gamma vector which, by means of a partial differential equation and a matrix transformation relation, can be used in calculating the gamma vector in physical regions where the hypergeometric functions are nonconvergent or very slowly converging. Our matrix transformation relation contains the special cases of Gauss' hypergeometric functions 2 F 1 , Appell's hypergeometric functions F 2 , and Lauricella's functions L F transformation relations. The use of contiguous relations along with the transformation relations presented in this paper will facilitate the calculation of physical processes involving such radial integrals
International Nuclear Information System (INIS)
Yu Fajun
2008-01-01
In [W.X. Ma, J. Phys. A: Math. Theor. 40 (2007) 15055], Prof. Ma gave a beautiful result (a discrete variational identity). In this Letter, based on a discrete block matrix spectral problem, a new hierarchy of Lax integrable lattice equations with four potentials is derived. By using of the discrete variational identity, we obtain Hamiltonian structure of the discrete soliton equation hierarchy. Finally, an integrable coupling system of the soliton equation hierarchy and its Hamiltonian structure are obtained through the discrete variational identity
Energy Technology Data Exchange (ETDEWEB)
Yu Fajun [College of Maths and Systematic Science, Shenyang Normal University, Shenyang 110034 (China)], E-mail: yufajun888@163.com
2008-06-09
In [W.X. Ma, J. Phys. A: Math. Theor. 40 (2007) 15055], Prof. Ma gave a beautiful result (a discrete variational identity). In this Letter, based on a discrete block matrix spectral problem, a new hierarchy of Lax integrable lattice equations with four potentials is derived. By using of the discrete variational identity, we obtain Hamiltonian structure of the discrete soliton equation hierarchy. Finally, an integrable coupling system of the soliton equation hierarchy and its Hamiltonian structure are obtained through the discrete variational identity.
Bisetti, Fabrizio
2012-06-01
Recent trends in hydrocarbon fuel research indicate that the number of species and reactions in chemical kinetic mechanisms is rapidly increasing in an effort to provide predictive capabilities for fuels of practical interest. In order to cope with the computational cost associated with the time integration of stiff, large chemical systems, a novel approach is proposed. The approach combines an exponential integrator and Krylov subspace approximations to the exponential function of the Jacobian matrix. The components of the approach are described in detail and applied to the ignition of stoichiometric methane-air and iso-octane-air mixtures, here described by two widely adopted chemical kinetic mechanisms. The approach is found to be robust even at relatively large time steps and the global error displays a nominal third-order convergence. The performance of the approach is improved by utilising an adaptive algorithm for the selection of the Krylov subspace size, which guarantees an approximation to the matrix exponential within user-defined error tolerance. The Krylov projection of the Jacobian matrix onto a low-dimensional space is interpreted as a local model reduction with a well-defined error control strategy. Finally, the performance of the approach is discussed with regard to the optimal selection of the parameters governing the accuracy of its individual components. © 2012 Copyright Taylor and Francis Group, LLC.
Arnott, Stephanie
2011-01-01
Over the last decade, almost 4,000 Canadian schools have moved to using the Accelerative Integrated Method (AIM) for core French (CF) instruction. Following researchers' recommendations (Brumfit, 1984; Lapkin, Mady, & Arnott, 2009; Larsen-Freeman, 1996, 2000; Prahbu, 1990), I am shifting the focus in this case study from product to process. In…
Directory of Open Access Journals (Sweden)
Stephanie Arnott
2011-12-01
Full Text Available Abstract Over the last decade, almost 4,000 Canadian schools have moved to using the Accelerative Integrated Method (AIM for core French (CF instruction. Following researchers’ recommendations (Brumfit, 1984; Lapkin, Mady, & Arnott, 2009; Larsen-Freeman, 1996, 2000; Prahbu, 1990, I am shifting the focus in this case study from product to process. In other words, investigating how AIM teachers use and shape the method during implementation instead of comparing AIM and non-AIM student outcomes (Bourdages & Vignola, 2009; Carr, 2001; Mady, Arnott, & Lapkin, 2009; Maxwell, 2001; Michels, 2008;. Four interviews and observation sessions were conducted with eight elementary-level CF teachers. Findings showed that while some AIM routines and strategies were used by all, teachers exercised their agency in supplementing recommended AIM activities and materials, especially those with more AIM and CF teaching experience. Establishing that using AIM engaged teachers’ senses of plausibility (Prahbu, 1990 also exposed important implications for future AIM research and board-level policy. Résumé Depuis les années 2000, plus de 4000 écoles canadiennes ont decidé d’utiliser une forme d’enseignement qui s’appelle AIM (Accelerative Integrated Method pour leurs programmes de français de base (Core French. Selon les recommandations des chercheurs suivants (Brumfit, 1984; Lapkin, Mady, & Arnott, 2009; Larsen-Freeman, 1996, 2000; Prahbu, 1990, au lieu d’étudier les résultats, l’objectif de cette étude de cas était d’examiner la mise en œuvre de AIM. Huit enseignants de français de base ont passé quatre entrevues individuelles. Ils ont eu quatre sessions d’observation de pratique de AIM . Selon les résultats, quoiqu’ils aient employé des stratégies et routines de AIM de la même façon, tous les enseignants ont aussi décidé d’ajouter leurs propres activités et ressources à AIM, surtout ceux experts dans l’enseignement du fran
The Virasoro algebra in integrable hierarchies and the method of matrix models
International Nuclear Information System (INIS)
Semikhatov, A.M.
1992-01-01
The action of the Virasoro algebra on hierarchies of nonlinear integrable equations, and also the structure and consequences of Virasoro constraints on these hierarchies, are studied. It is proposed that a broad class of hierarchies, restricted by Virasoro constraints, can be defined in terms of dressing operators hidden in the structure of integrable systems. The Virasoro-algebra representation constructed on the dressing operators displays a number of analogies with structures in conformal field theory. The formulation of the Virasoro constraints that stems from this representation makes it possible to translate into the language of integrable systems a number of concepts from the method of the 'matrix models' that describe nonperturbative quantum gravity, and, in particular, to realize a 'hierarchical' version of the double scaling limit. From the Virasoro constraints written in terms of the dressing operators generalized loop equations are derived, and this makes it possible to do calculations on a reconstruction of the field-theoretical description. The reduction of the Kadomtsev-Petviashvili (KP) hierarchy, subject to Virasoro constraints, to generalized Korteweg-deVries (KdV) hierarchies is implemented, and the corresponding representation of the Virasoro algebra on these hierarchies is found both in the language of scalar differential operators and in the matrix formalism of Drinfel'd and Sokolov. The string equation in the matrix formalism does not replicate the structure of the scalar string equation. The symmetry algebras of the KP and N-KdV hierarchies restricted by Virasoro constraints are calculated: A relationship is established with algebras from the family W ∞ (J) of infinite W-algebras
Number-conserving random phase approximation with analytically integrated matrix elements
International Nuclear Information System (INIS)
Kyotoku, M.; Schmid, K.W.; Gruemmer, F.; Faessler, A.
1990-01-01
In the present paper a number conserving random phase approximation is derived as a special case of the recently developed random phase approximation in general symmetry projected quasiparticle mean fields. All the occurring integrals induced by the number projection are performed analytically after writing the various overlap and energy matrices in the random phase approximation equation as polynomials in the gauge angle. In the limit of a large number of particles the well-known pairing vibration matrix elements are recovered. We also present a new analytically number projected variational equation for the number conserving pairing problem
Matrix based method for synthesis of main intensified and integrated distillation sequences
International Nuclear Information System (INIS)
Khalili-Garakani, Amirhossein; Kasiri, Norollah; Ivakpour, Javad
2016-01-01
The objective of many studies in this area has involved access to a column-sequencing algorithm enabling designers and researchers alike to generate a wide range of sequences in a broad search space, and be as mathematically and as automated as possible for programing purposes and with good generality. In the present work an algorithm previously developed by the authors, called the matrix method, has been developed much further. The new version of the algorithm includes thermally coupled, thermodynamically equivalent, intensified, simultaneous heat and mass integrated and divided-wall column sequences which are of gross application and provide vast saving potential both on capital investment, operating costs and energy usage in industrial applications. To demonstrate the much wider searchable space now accessible, a three component separation has been thoroughly examined as a case study, always resulting in an integrated sequence being proposed as the optimum.
Integrating indicators in a national accounting matrix including environmental accounts (NAMEA)
International Nuclear Information System (INIS)
De Haan, M.; Keuning, S.J.; Bosch, P.R.
1993-01-01
Five environmental indicators are conceptually and numerically integrated into a National Accounting Matrix including Environmental Accounts (NAMEA) for 1989. As a consequence, these estimates are directly comparable with outcomes of major macro-economic aggregates in the conventional accounts. In the NAMEA, emissions of all kinds of polluting agents are recorded by industry and by consumption purpose. Subsequently, these agents are grouped into five environmental themes: greenhouse effect, ozone layer depletion, acidification, eutrophication and waste accumulation. The contributions of agents to certain themes are expressed in theme-related environmental stress equivalents. Per theme, these stress equivalents are confronted with policy norms set by the Netherlands government for the year 2000. This results in a statistical framework at a meso-level from which integrated economic and environmental indicators are derived. The NAMEA may also serve as a data base and analytical device for modelling interactions between the national economy and changes in the environment. 13 tabs., 2 app., 32 refs
Improved Fabrication of Ceramic Matrix Composite/Foam Core Integrated Structures
Hurwitz, Frances I.
2009-01-01
The use of hybridized carbon/silicon carbide (C/SiC) fabric to reinforce ceramic matrix composite face sheets and the integration of such face sheets with a foam core creates a sandwich structure capable of withstanding high-heatflux environments (150 W/cm2) in which the core provides a temperature drop of 1,000 C between the surface and the back face without cracking or delamination of the structure. The composite face sheet exhibits a bilinear response, which results from the SiC matrix not being cracked on fabrication. In addition, the structure exhibits damage tolerance under impact with projectiles, showing no penetration to the back face sheet. These attributes make the composite ideal for leading edge structures and control surfaces in aerospace vehicles, as well as for acreage thermal protection systems and in high-temperature, lightweight stiffened structures. By tailoring the coefficient of thermal expansion (CTE) of a carbon fiber containing ceramic matrix composite (CMC) face sheet to match that of a ceramic foam core, the face sheet and the core can be integrally fabricated without any delamination. Carbon and SiC are woven together in the reinforcing fabric. Integral densification of the CMC and the foam core is accomplished with chemical vapor deposition, eliminating the need for bond-line adhesive. This means there is no need to separately fabricate the core and the face sheet, or to bond the two elements together, risking edge delamination during use. Fibers of two or more types are woven together on a loom. The carbon and ceramic fibers are pulled into the same pick location during the weaving process. Tow spacing may be varied to accommodate the increased volume of the combined fiber tows while maintaining a target fiber volume fraction in the composite. Foam pore size, strut thickness, and ratio of face sheet to core thickness can be used to tailor thermal and mechanical properties. The anticipated CTE for the hybridized composite is managed by
USING MATRIX METHODS OF PORTFOLIO ANALYSIS IN DESIGNING VERTICAL-INTEGRATED BUILDING STRUCTURE
Directory of Open Access Journals (Sweden)
Rakytska S.
2018-01-01
Full Text Available Introduction. Ensuring productive functioning of corporations requires assessment and management decisions in terms of choosing effective areas of its activities. Purpose. Investigation of the possibilities of using matrix methods in the formation of a business portfolio in order to create a vertically-integrated structure in the construction complex. Results. Portfolio analysis is an effective tool, first of all, for functionally flexible, “many grocery” companies, who have the opportunity to quickly make changes to their business portfolio. For the production of the final construction product, you need the entire technological chain – from the supplier of primary raw materials, to the implementation and further maintenance of finished products. The strategy of the integrated structure is designed to: coordinate the objectives of the merged enterprises, determine the degree of their interaction, maximize the effect of the integration of business entities, develop ways to react newly formed corporation to changes taking place in the external environment, determine the most effective way of its development time, to ensure the competitive advantages of an integrated structure. The construction of a complex multi-level corporation in a building complex requires the development of a certain algorithm of action, which will ensure the optimality of the newly created structure and effective functioning.
Energy Technology Data Exchange (ETDEWEB)
Fink, Alexander; Rammig, Hanna [ScMI AG Paderborn (Germany)
2013-02-15
The national sustainability strategy (NHS) shall significantly shape the direction of the sustainable development in Germany. It is aim of the project ''Development of integrated scenarios to attain the environmental aims of the national sustainability strategy'' to develop different options, of how to possibly approach the environmental aims of the national sustainability strategy. In a first step external scenarios were developed, which describe the national sustainability strategy. In a first step external scenarios were developed, which describe the external context for the embodiment of sustainability. In a second step, option scenarios which show alternatives for different actor groups were built for the three areas ''Leisure time, living and alimentation''. In a third step the combination of the different external scenarios and internal options has been conducted, how do the different solution areas fit to the external scenarios.
ImWalkMF: Joint matrix factorization and implicit walk integrative learning for recommendation
Zhang, Chuxu
2018-01-15
Data sparsity and cold-start problems are prevalent in recommender systems. To address such problems, both the observable explicit social information (e.g., user-user trust connections) and the inferable implicit correlations (e.g., implicit neighbors computed by similarity measurement) have been introduced to complement user-item ratings data for improving the performances of traditional model-based recommendation algorithms such as matrix factorization. Although effective, (1) the utilization of the explicit user-user social relationships suffers from the weakness of unavailability in real systems such as Netflix or the issue of sparse observable content like 0.03% trust density in Epinions, thus there is no or little explicit social information that can be employed to improve baseline model in real applications; (2) the current similarity measurement approaches focus on inferring implicit correlations between a user (item) and their direct neighbors or top-k similar neighbors based on user-item ratings bipartite network, so that they fail to comprehensively unfold the indirect potential relationships among users and items. To solve these issues regarding both explicit/implicit social recommendation algorithms, we design a joint model of matrix factorization and implicit walk integrative learning, i.e., ImWalkMF, which only uses explicit ratings information yet models both direct rating feedbacks and multiple direct/indirect implicit correlations among users and items from a random walk perspective. We further propose a combined strategy for training two independent components in the proposed model based on sampling. The experimental results on two real-world sparse datasets demonstrate that ImWalkMF outperforms the traditional regularized/probabilistic matrix factorization models as well as other competitive baselines that utilize explicit/implicit social information.
International Nuclear Information System (INIS)
Haghiashtiani, Ghazaleh; Greminger, Michael A
2015-01-01
The focus of this work is to evaluate a new carbon fiber reinforced composite structure with integrated sensing capabilities. In this composite structure, the typical matrix material used for carbon fiber reinforced composites is replaced with the thermoplastic polyvinylidene difluoride (PVDF). Since PVDF has piezoelectric properties, it enables the structure to be used for integrated load sensing. In addition, the electrical conductivity property of the carbon fabric is harnessed to form the electrodes of the integrated sensor. In order to prevent the carbon fiber electrodes from shorting to each other, a thin Kevlar fabric layer is placed between the two carbon fiber electrode layers as a dielectric. The optimal polarization parameters were determined using a design of experiments approach. Once polarized, the samples were then used in compression and tensile tests to determine the effective d 33 and d 31 piezoelectric coefficients. The degree of polarization of the PVDF material was determined by relating the effective d 33 coefficient of the composite to the achieved d 33 of the PVDF component of the composite using a closed form expression. Using this approach, it was shown that optimal polarization of the composite material results in a PVDF component d 33 of 3.2 pC N −1 . Moreover, the Young’s modulus of the composite structure has been characterized. (paper)
Grassmann integral and Balian–Brézin decomposition in Hartree–Fock–Bogoliubov matrix elements
Energy Technology Data Exchange (ETDEWEB)
Mizusaki, Takahiro, E-mail: mizusaki@isc.senshu-u.ac.jp [Institute of Natural Sciences, Senshu University, 3-8-1 Kanda-Jinbocho, Chiyoda-ku, Tokyo 101-8425 (Japan); Oi, Makito [Institute of Natural Sciences, Senshu University, 3-8-1 Kanda-Jinbocho, Chiyoda-ku, Tokyo 101-8425 (Japan); Chen, Fang-Qi [Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai 200240 (China); Sun, Yang [Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai 200240 (China); Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China)
2013-08-09
We present a new formula to calculate matrix elements of a general unitary operator with respect to Hartree–Fock–Bogoliubov states allowing multiple quasi-particle excitations. The Balian–Brézin decomposition of the unitary operator [R. Balian, E. Brézin, Il Nuovo Cimento B 64 (1969) 37] is employed in the derivation. We found that this decomposition is extremely suitable for an application of Fermion coherent state and Grassmann integrals in the quasi-particle basis. The resultant formula is compactly expressed in terms of the Pfaffian, and shows the similar bipartite structure to the formula that we have previously derived in the bare-particles basis [T. Mizusaki, M. Oi, Phys. Lett. B 715 (2012) 219].
Directory of Open Access Journals (Sweden)
Bisakha Ray
2017-08-01
Full Text Available The amounts and types of available multimodal tumor data are rapidly increasing, and their integration is critical for fully understanding the underlying cancer biology and personalizing treatment. However, the development of methods for effectively integrating multimodal data in a principled manner is lagging behind our ability to generate the data. In this article, we introduce an extension to a multiview nonnegative matrix factorization algorithm (NNMF for dimensionality reduction and integration of heterogeneous data types and compare the predictive modeling performance of the method on unimodal and multimodal data. We also present a comparative evaluation of our novel multiview approach and current data integration methods. Our work provides an efficient method to extend an existing dimensionality reduction method. We report rigorous evaluation of the method on large-scale quantitative protein and phosphoprotein tumor data from the Clinical Proteomic Tumor Analysis Consortium (CPTAC acquired using state-of-the-art liquid chromatography mass spectrometry. Exome sequencing and RNA-Seq data were also available from The Cancer Genome Atlas for the same tumors. For unimodal data, in case of breast cancer, transcript levels were most predictive of estrogen and progesterone receptor status and copy number variation of human epidermal growth factor receptor 2 status. For ovarian and colon cancers, phosphoprotein and protein levels were most predictive of tumor grade and stage and residual tumor, respectively. When multiview NNMF was applied to multimodal data to predict outcomes, the improvement in performance is not overall statistically significant beyond unimodal data, suggesting that proteomics data may contain more predictive information regarding tumor phenotypes than transcript levels, probably due to the fact that proteins are the functional gene products and therefore a more direct measurement of the functional state of the tumor. Here, we
H∞ Control of Coronary Artery Input Time-Delay System via the Free-Matrix-Based Integral Inequality
Directory of Open Access Journals (Sweden)
Sha-sha Li
2018-01-01
Full Text Available The issue of H∞ control for the coronary artery input time-delay system with external disturbance is of concern. To further reduce conservation, we utilize the free-matrix-based integral inequality, Wirtinger-based integral inequality, and reciprocal convex combination approach to construct Lyapunov-Krasovskii function (LKF. Then a sufficient condition for controller design which can guarantee robust synchronization the coronary artery system is represented in terms of linear matrix inequality (LMI. Finally, a numerical example is exploited to show the effectiveness of the proposed methods.
Virasoro algebra action on integrable hierarchies and Virasoro contraints in matrix models
International Nuclear Information System (INIS)
Semikhatov, A.M.
1991-01-01
The action of the Virasoro algebra on integrable hierarchies of non-linear equations and on related objects ('Schroedinger' differential operators) is investigated. The method consists in pushing forward the Virasoro action to the wave function of a hierarchy, and then reconstructing its action on the dressing and Lax operators. This formulation allows one to observe a number of suggestive similarities between the structures involved in the description of the Virasoro algebra on the hierarchies and the structure of conformal field theory on the world-sheet. This includes, in particular, an 'off-shell' hierarchy version of operator products and of the Cauchy kernel. In relation to matrix models, which have been observed to be effectively described by integrable hierarchies subjected to Virasoro constraints, I propose to define general Virasoro-constrained hierarchies also in terms of dressing operators, by certain equations which carry the information of the hierarchy and the Virasoro algebra simultaneously and which suggest an interpretation as operator versions of recursion/loop equations in topological theories. These same equations provide a relation with integrable hierarchies with quantized spectral parameter introduced recently. The formulation in terms of dressing operators allows a scaling (continuum limit) of discrete (i.e. lattice) hierarchies with the Virasoro constraints into 'continuous' Virasoro-constrained hierarchies. In particular, the KP hierarchy subjected to the Virasoro constraints is recovered as a scaling limit of the Virasoro-constrained Toda hierarchy. The dressing operator method also makes is straightforward to identify the full symmetry algebra of Virasoro-constrained hierarchies, which is related to the family of W ∞ (J) algebras introduced recently. (orig./HS)
Saw, Anne; Kim, Jin; Lim, Joyce; Powell, Catherine; Tong, Elisa K.
2016-01-01
Engagement in modifiable risk behaviors, such as tobacco use, substantially contributes to early mortality rates in individuals with serious mental illness (SMI). There is an alarmingly high prevalence of tobacco use among subgroups of Asian Americans, such as immigrants and individuals with SMI, yet there are no empirically supported effective smoking cessation interventions that have been tailored to meet the unique cultural, cognitive, and psychological needs of Asian immigrants with SMI. In this article, we share the experiences of clinicians in the delivery of smoking cessation counseling to Asian American immigrants with SMI, in the context of an Asian-focused integrated primary care and behavioral health setting. Through a qualitative analysis of clinician perspectives organized with the RE-AIM framework, we outline challenges, lessons learned, and promising directions for delivering smoking cessation counseling to Asian American immigrant clients with SMI. PMID:23667056
Saw, Anne; Kim, Jin; Lim, Joyce; Powell, Catherine; Tong, Elisa K
2013-09-01
Engagement in modifiable risk behaviors, such as tobacco use, substantially contributes to early mortality rates in individuals with serious mental illness (SMI). There is an alarmingly high prevalence of tobacco use among subgroups of Asian Americans, such as immigrants and individuals with SMI, yet there are no empirically supported effective smoking cessation interventions that have been tailored to meet the unique cultural, cognitive, and psychological needs of Asian immigrants with SMI. In this article, we share the experiences of clinicians in the delivery of smoking cessation counseling to Asian American immigrants with SMI, in the context of an Asian-focused integrated primary care and behavioral health setting. Through a qualitative analysis of clinician perspectives organized with the RE-AIM framework, we outline challenges, lessons learned, and promising directions for delivering smoking cessation counseling to Asian American immigrant clients with SMI.
Energy Technology Data Exchange (ETDEWEB)
Katz, Daniel S [Univ. of Illinois, Urbana-Champaign, IL (United States). National Center for Supercomputing Applications (NCSA); Jha, Shantenu [Rutgers Univ., New Brunswick, NJ (United States); Weissman, Jon [Univ. of Minnesota, Minneapolis, MN (United States); Turilli, Matteo [Rutgers Univ., New Brunswick, NJ (United States)
2017-01-31
This is the final technical report for the AIMES project. Many important advances in science and engineering are due to large-scale distributed computing. Notwithstanding this reliance, we are still learning how to design and deploy large-scale production Distributed Computing Infrastructures (DCI). This is evidenced by missing design principles for DCI, and an absence of generally acceptable and usable distributed computing abstractions. The AIMES project was conceived against this backdrop, following on the heels of a comprehensive survey of scientific distributed applications. AIMES laid the foundations to address the tripartite challenge of dynamic resource management, integrating information, and portable and interoperable distributed applications. Four abstractions were defined and implemented: skeleton, resource bundle, pilot, and execution strategy. The four abstractions were implemented into software modules and then aggregated into the AIMES middleware. This middleware successfully integrates information across the application layer (skeletons) and resource layer (Bundles), derives a suitable execution strategy for the given skeleton and enacts its execution by means of pilots on one or more resources, depending on the application requirements, and resource availabilities and capabilities.
A Three-Phase Dual-Input Matrix Converter for Grid Integration of Two AC Type Energy Resources
DEFF Research Database (Denmark)
Liu, Xiong; Wang, Peng; Chiang Loh, Poh
2013-01-01
This paper proposes a novel dual-input matrix converter (DIMC) to integrate two three-phase ac type energy resources to a power grid. The proposed matrix converter is developed based on the traditional indirect matrix converter under reverse power flow operation mode, but with its six......-to-output voltage boost capability since power flows from the converter’s voltage source side to its current source side. Commanded currents can be extracted from the two input sources to the grid. The proposed control and modulation schemes guarantee sinusoidal input and output waveforms as well as unity input......-switch voltage source converter replaced by a nine-switch configuration. With the additional three switches, the proposed DIMC can provide six in put terminals, which make it possible to integrate two independent ac sources into a single grid-tied power electronics interface. The proposed converter has input...
Coburn, J.; Gibson, M.; Bandalini, P.A.; Laird, C.; Mao, H.Q.; Moroni, Lorenzo; Seliktar, D.; Elisseeff, J.H.
2011-01-01
The native extracellular matrix (ECM) consists of an integrated fibrous protein network and proteoglycan-based ground (hydrogel) substance. We designed a novel electrospinning technique to engineer a three dimensional fiber-hydrogel composite that mimics the native ECM structure, is injectable, and
Berge, Jerica M; Adamek, Margaret; Caspi, Caitlin; Grannon, Katherine Y; Loth, Katie A; Trofholz, Amanda; Nanney, Marilyn S
2018-06-01
In response to the limitations of siloed weight-related intervention approaches, scholars have called for greater integration that is intentional, strategic, and thoughtful between researchers, health care clinicians, community members, and policy makers as a way to more effectively address weight and weight-related (e.g., obesity, diabetes, cardiovascular disease, cancer) public health problems. The Mastery Matrix for Integration Praxis was developed by the Healthy Eating and Activity across the Lifespan (HEAL) team in 2017 to advance the science and praxis of integration across the domains of research, clinical practice, community, and policy to address weight-related public health problems. Integrator functions were identified and developmental stages were created to generate a rubric for measuring mastery of integration. Creating a means to systematically define and evaluate integration praxis and expertise will allow for more individuals and teams to master integration in order to work towards promoting a culture of health. Copyright © 2018 Elsevier Inc. All rights reserved.
Integration of SWPF into the DWPF Flowsheet: Gap Analysis and Test Matrix Development
Energy Technology Data Exchange (ETDEWEB)
Peeler, D. K. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Edwards, T. B. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)
2014-12-10
Based on Revision 19 of the High Level Waste (HLW) System Plan, it is anticipated that the Salt Waste Processing Facility (SWPF) will be integrated into the Defense Waste Processing Facility (DWPF) flowsheet in October 2018 (or with Sludge Batch 11 (SB11)). Given that, Savannah River Remediation (SRR) has requested a technical basis be developed that validates the current Product Composition Control System (PCCS) models for use during the processing of the SWPF-based coupled flowsheet or that leads to the refinements of or modifications to the models that are needed so that the models may be used during the processing of the SWPF-based coupled flowsheet. To support this objective, Savannah River National Laboratory (SRNL) has completed three key interim activities prior to validation of the current or development of refined PCCS models over the anticipated glass composition region for SWPF processing. These three key activities include: (1) defining the glass compositional region over which SWPF is anticipated to be processed, (2) comparing the current PCCS model validation ranges to the SWPF glass compositional region from which compositional gaps can be identified, and (3) developing a test matrix to cover the compositional gaps.
Directory of Open Access Journals (Sweden)
Jianping Liu
2016-01-01
Full Text Available An operational matrix technique is proposed to solve variable order fractional differential-integral equation based on the second kind of Chebyshev polynomials in this paper. The differential operational matrix and integral operational matrix are derived based on the second kind of Chebyshev polynomials. Using two types of operational matrixes, the original equation is transformed into the arithmetic product of several dependent matrixes, which can be viewed as an algebraic system after adopting the collocation points. Further, numerical solution of original equation is obtained by solving the algebraic system. Finally, several examples show that the numerical algorithm is computationally efficient.
Development of an integrated system for activity-based profiling of matrix metallo-proteases
Freije, Jan Robert
2006-01-01
Matrix metallo-proteases constitute a family of extracellular zinc-dependent endopeptidases that are involved in degradation of extracellular matrix (ECM) components and other bioactive non-ECM molecules. A plethora of studies have implicated important roles for MMPs in many diseases (including
Integrative systems and synthetic biology of cell-matrix adhesion sites.
Zamir, Eli
2016-09-02
The complexity of cell-matrix adhesion convolves its roles in the development and functioning of multicellular organisms and their evolutionary tinkering. Cell-matrix adhesion is mediated by sites along the plasma membrane that anchor the actin cytoskeleton to the matrix via a large number of proteins, collectively called the integrin adhesome. Fundamental challenges for understanding how cell-matrix adhesion sites assemble and function arise from their multi-functionality, rapid dynamics, large number of components and molecular diversity. Systems biology faces these challenges in its strive to understand how the integrin adhesome gives rise to functional adhesion sites. Synthetic biology enables engineering intracellular modules and circuits with properties of interest. In this review I discuss some of the fundamental questions in systems biology of cell-matrix adhesion and how synthetic biology can help addressing them.
Poduska, Jeanne; Kellam, Sheppard; Brown, C Hendricks; Ford, Carla; Windham, Amy; Keegan, Natalie; Wang, Wei
2009-09-02
While a number of preventive interventions delivered within schools have shown both short-term and long-term impact in epidemiologically based randomized field trials, programs are not often sustained with high-quality implementation over time. This study was designed to support two purposes. The first purpose was to test the effectiveness of a universal classroom-based intervention, the Whole Day First Grade Program (WD), aimed at two early antecedents to drug abuse and other problem behaviors, namely, aggressive, disruptive behavior and poor academic achievement. The second purpose--the focus of this paper--was to examine the utility of a multilevel structure to support high levels of implementation during the effectiveness trial, to sustain WD practices across additional years, and to train additional teachers in WD practices. The WD intervention integrated three components, each previously tested separately: classroom behavior management; instruction, specifically reading; and family-classroom partnerships around behavior and learning. Teachers and students in 12 schools were randomly assigned to receive either the WD intervention or the standard first-grade program of the school system (SC). Three consecutive cohorts of first graders were randomized within schools to WD or SC classrooms and followed through the end of third grade to test the effectiveness of the WD intervention. Teacher practices were assessed over three years to examine the utility of the multilevel structure to support sustainability and scaling-up. The design employed in this trial appears to have considerable utility to provide data on WD effectiveness and to inform the field with regard to structures required to move evidence-based programs into practice. NCT00257088.
Directory of Open Access Journals (Sweden)
Keegan Natalie
2009-09-01
Full Text Available Abstract Background While a number of preventive interventions delivered within schools have shown both short-term and long-term impact in epidemiologically based randomized field trials, programs are not often sustained with high-quality implementation over time. This study was designed to support two purposes. The first purpose was to test the effectiveness of a universal classroom-based intervention, the Whole Day First Grade Program (WD, aimed at two early antecedents to drug abuse and other problem behaviors, namely, aggressive, disruptive behavior and poor academic achievement. The second purpose--the focus of this paper--was to examine the utility of a multilevel structure to support high levels of implementation during the effectiveness trial, to sustain WD practices across additional years, and to train additional teachers in WD practices. Methods The WD intervention integrated three components, each previously tested separately: classroom behavior management; instruction, specifically reading; and family-classroom partnerships around behavior and learning. Teachers and students in 12 schools were randomly assigned to receive either the WD intervention or the standard first-grade program of the school system (SC. Three consecutive cohorts of first graders were randomized within schools to WD or SC classrooms and followed through the end of third grade to test the effectiveness of the WD intervention. Teacher practices were assessed over three years to examine the utility of the multilevel structure to support sustainability and scaling-up. Discussion The design employed in this trial appears to have considerable utility to provide data on WD effectiveness and to inform the field with regard to structures required to move evidence-based programs into practice. Trial Registration Clinical Trials Registration Number: NCT00257088
International Nuclear Information System (INIS)
Jowzani-Moghaddam, A.
1981-01-01
An integral transport method of calculating the geometrical shadowing factor in multiregion annular cells for infinite closely packed lattices in cylindrical geometry is developed. This analytical method has been programmed in the TPGS code. This method is based upon a consideration of the properties of the integral transport method for a nonuniform body, which together with Bonalumi's approximations allows the determination of the approximate multiregion collision probability matrix for infinite closely packed lattices with sufficient accuracy. The multiregion geometrical shadowing factors have been calculated for variations in fuel pin annular segment rings in a geometry of annular cells. These shadowing factors can then be used in the calculation of neutron transport from one annulus to another in an infinite lattice. The result of this new geometrical shadowing and collision probability matrix are compared with the Dancoff-Ginsburg correction and the probability matrix using constant shadowing on Yankee fuel elements in an infinite lattice. In these cases the Dancoff-Ginsburg correction factor and collision probability matrix using constant shadowing are in difference by at most 6.2% and 6%, respectively
Directory of Open Access Journals (Sweden)
Van Anh Thi Nguyen
2014-06-01
Full Text Available This study aimed to diagnose the situation productive of charcoal in Pinar del Río EFI by SWOT matrix (weaknesses, threats, strengths and opportunities which consists of the collection of information from different sources related to the production of charcoal and thus a screening of ideas and through the technical working group with the presence of specialists proceeded develop the matrix with all components was performed. The results of the assessment of the productive situation of charcoal indicate an unfavorable position, resulting in a strategy of adaptive type, conditioned by economic, political and cultural factors.
Sorokin, Sergey V
2011-03-01
Helical springs serve as vibration isolators in virtually any suspension system. Various exact and approximate methods may be employed to determine the eigenfrequencies of vibrations of these structural elements and their dynamic transfer functions. The method of boundary integral equations is a meaningful alternative to obtain exact solutions of problems of the time-harmonic dynamics of elastic springs in the framework of Bernoulli-Euler beam theory. In this paper, the derivations of the Green's matrix, of the Somigliana's identities, and of the boundary integral equations are presented. The vibrational power transmission in an infinitely long spring is analyzed by means of the Green's matrix. The eigenfrequencies and the dynamic transfer functions are found by solving the boundary integral equations. In the course of analysis, the essential features and advantages of the method of boundary integral equations are highlighted. The reported analytical results may be used to study the time-harmonic motion in any wave guide governed by a system of linear differential equations in a single spatial coordinate along its axis. © 2011 Acoustical Society of America
Short term braking capability during power interruptions for integrated matrix converter
DEFF Research Database (Denmark)
Klumpner, Christian; Blaabjerg, Frede
2004-01-01
attractive. Sinusoidal input currents and bi-directional power flow are other advantages of the matrix converter, but it is less immune to power grid disturbances compared to a standard ASD. In hoisting applications, short-term braking capability during a power outage is needed until the mechanical brake...... engages or to perform more effective a combined braking. This paper proposes a new method to provide short-term braking capability during a power outage for matrix converters. A braking chopper is needed in the clamp circuit, which allows for a drastically reduction of the capacitor size. The power flow...
DEFF Research Database (Denmark)
Klumpner, Christian; Blaabjerg, Frede
2002-01-01
attractive. Sinusoidal input currents and bi-directional power flow are other advantages of the matrix converter but it is less immune to power grid disturbances compared to a standard ASD. In hoisting applications, short-term braking capability during a power outage is needed until the mechanical brake...... engages or to perform more effective a combined braking.This paper proposes a new method to provide short-term braking capability during a power outage for matrix converters. A braking chopper is needed in the clamp circuit, which allows for a drastically reduction of the capacitor size. The power flow...
Somme, Dominique; de Stampa, Matthieu; Périsset, Catherine; Dupont, Olivier; Ankri, Joël; Saint-Jean, Olivier
2009-01-01
Introduction The French Alzheimer plan, states that one of its principle orientations is the implementation of ‘Homes for Integration and Autonomy for Alzheimer patients’. Alzheimer disease is taken as a model to implement integration for all persons in complex situation (handicap…). Method Seventeen experimental sites were selected in January 2009 for the first two years. They were selected by policy-makers taking into account the readiness of the local policy-makers to implement the program, the diversity of sizes of sites, the diversity of the experimentation leaders' organizational link (public administrations, not for profit organizations, private organizations) and the diversity of societal structure (rural, urban and mega-urban). The experimental sites were analyzed considering six components of integration: coordination boards, unique point of access, case-management, standardized assessment tool, individualized services plan and information system. A complete and computerized tool was specifically developed for the organizational diagnosis. Results During the session, results will be exposed. These results will give a contrasted image of the French system for persons in complex situation. The tool will be also exposed and the receptivity will be discussed. Conclusion The French Alzheimer plan gives a unique opportunity to have a portrait of the French system in regard of integration challenges.
International Nuclear Information System (INIS)
1996-07-01
This report deals with an internationally agreed integral test facility (ITF) matrix for the validation of best estimate thermal-hydraulic computer codes. Firstly, the main physical phenomena that occur during the considered accidents are identified, test types are specified, and test facilities suitable for reproducing these aspects are selected. Secondly, a life of selected experiments carried out in these facilities has been set down. The criteria to achieve the objectives are outlined. The construction of such a matrix is an attempt to collect together in a systematic way the best sets of openly available test data for code validation, assessment and improvement, including quantitative assessment of uncertainties in the modelling of phenomena by the codes. In addition to this objective, it is an attempt to record information which has been generated around the world over the last 20 years so that it is more accessible to present and future workers in that field than would otherwise be the case
Two hierarchies of integrable lattice equations associated with a discrete matrix spectral problem
International Nuclear Information System (INIS)
Li Xinyue; Xu Xixiang; Zhao Qiulan
2008-01-01
Two hierarchies of nonlinear integrable positive and negative lattice models are derived from a discrete spectral problem. The two lattice hierarchies are proved to have discrete zero curvature representations associated with a discrete spectral problem, which also shows that the positive and negative hierarchies correspond to positive and negative power expansions of Lax operators with respect to the spectral parameter, respectively. Moreover, the integrable lattice models in the positive hierarchy are of polynomial type, and the integrable lattice models in the negative hierarchy are of rational type. Further, we construct infinite conservation laws of the positive hierarchy, then, the integrable coupling systems of the positive hierarchy are derived from enlarging Lax pair
International Nuclear Information System (INIS)
Lu, Guo-Shin; You, Po-Chin; Lin, Kai-Lun; Hong, Chien-Chong; Liou, Tong-Miin
2014-01-01
This paper presents a self-aligning ink by integrating an inkjet printing technique and heterostructures to fabricate a black matrix with a micrometer-scale tunable thickness. The black matrix is a grid-like structure used in color filters. Traditionally, a black matrix has been fabricated using photolithography techniques, the disadvantages of which are high material consumption, less fabrication flexibility, complex processing procedures, and high chemical pollution. Inkjet printing technology has garnered attention because of its low material costs, high fabrication flexibility, and reduced processing procedures and pollution. In this study, a fabricating process combining an inkjet printing technique with heterostructures to form stripe-arranged and delta-arranged thickness-tunable black matrices has been demonstrated. The deformation and self-aligning process of ink droplet impingement onto gutters are driven by designed heterogeneous surface properties. The minimum track width attained is 10 µm, which is competitive for color filter resolutions for thin-film transistor liquid crystal displays. The developed technology surmounts the bottlenecks of inkjet printing resolution, and saves more than 75% black material than modern photolithography. (paper)
A new soft dielectric silicone elastomer matrix with high mechanical integrity and low losses
DEFF Research Database (Denmark)
Madsen, Frederikke Bahrt; Yu, Liyun; Daugaard, Anders Egede
2015-01-01
Though dielectric elastomers (DEs) have many favourable properties, the issue of high driving voltages limits the commercial viability of the technology. Driving voltage can be lowered by decreasing the Young's modulus and increasing the dielectric permittivity of silicone elastomers. A decrease...... in Young's modulus, however, is often accompanied by the loss of mechanical stability and thereby the lifetime of the DE. A new soft elastomer matrix, with no loss of mechanical stability and high dielectric permittivity, was prepared through the use of alkyl chloride-functional siloxane copolymers...
Lamb, Alastair D; Thompson, Sue; Kinsella, Netty; Gerbitz, Ingmar; Chapman, Elaine; Putt, Lisa; Bennett, Sophie; Thankappannair, Vineetha; Geoghegan, Lisa; Wright, Naomi; Stirton-Croft, Alison; Nixon, Penny; Styling, Andrew; Whitney, Diane; Hodgson, Lindsay; Punt, Lisa; Longmore, Jenny; Carter, Mike; Petch, Bill; Rimmer, Yvonne; Russell, Simon; Hughes-Davies, Luke; Mazhar, Danish; Shah, Nimish C; Gnanapragasam, Vincent J; Doble, Andrew; Bratt, Ola; Kastner, Christof
2017-08-01
To establish a comprehensive set of recommendations for the service structure and skill set of nurses and allied healthcare professionals in prostate cancer care. Using components of formal consensus methodology, a 30-member multidisciplinary panel produced 53 items for discussion relating to the provision of care for prostate cancer patients by specialist nurses and allied healthcare professionals. Items were developed by two rounds of email correspondence in which, first, items were generated and, second, items refined to form the basis of a consensus meeting which constituted the third round of review. The fourth and final round was an email review of the consensus output. The panel agreed on 33 items that were appropriate for recommendations to be made. These items were grouped under categories of "Environment" and "Patient Pathway" and included comments on training, leadership, communication and quality assessment as well as specific items related to prostate diagnosis clinics, radical treatment clinics and follow-up survivor groups. Specialist nurses and allied healthcare professionals play a vital role alongside urologists and oncologists to provide care to men with prostate cancer and their families. We present a set of standards and consensus recommendations for the roles and skill-set required for these practitioners to provide gold-standard prostate cancer care. These recommendations could form the basis for development of comprehensive integrated prostate cancer pathways in prostate cancer centres as well as providing guidance for any units treating men with prostate cancer. Copyright © 2017. Published by Elsevier Ltd.
Hoy, Erik P; Mazziotti, David A
2015-08-14
Tensor factorization of the 2-electron integral matrix is a well-known technique for reducing the computational scaling of ab initio electronic structure methods toward that of Hartree-Fock and density functional theories. The simplest factorization that maintains the positive semidefinite character of the 2-electron integral matrix is the Cholesky factorization. In this paper, we introduce a family of positive semidefinite factorizations that generalize the Cholesky factorization. Using an implementation of the factorization within the parametric 2-RDM method [D. A. Mazziotti, Phys. Rev. Lett. 101, 253002 (2008)], we study several inorganic molecules, alkane chains, and potential energy curves and find that this generalized factorization retains the accuracy and size extensivity of the Cholesky factorization, even in the presence of multi-reference correlation. The generalized family of positive semidefinite factorizations has potential applications to low-scaling ab initio electronic structure methods that treat electron correlation with a computational cost approaching that of the Hartree-Fock method or density functional theory.
Energy Technology Data Exchange (ETDEWEB)
Hoy, Erik P.; Mazziotti, David A., E-mail: damazz@uchicago.edu [Department of Chemistry and The James Franck Institute, The University of Chicago, Chicago, Illinois 60637 (United States)
2015-08-14
Tensor factorization of the 2-electron integral matrix is a well-known technique for reducing the computational scaling of ab initio electronic structure methods toward that of Hartree-Fock and density functional theories. The simplest factorization that maintains the positive semidefinite character of the 2-electron integral matrix is the Cholesky factorization. In this paper, we introduce a family of positive semidefinite factorizations that generalize the Cholesky factorization. Using an implementation of the factorization within the parametric 2-RDM method [D. A. Mazziotti, Phys. Rev. Lett. 101, 253002 (2008)], we study several inorganic molecules, alkane chains, and potential energy curves and find that this generalized factorization retains the accuracy and size extensivity of the Cholesky factorization, even in the presence of multi-reference correlation. The generalized family of positive semidefinite factorizations has potential applications to low-scaling ab initio electronic structure methods that treat electron correlation with a computational cost approaching that of the Hartree-Fock method or density functional theory.
Integrable light-cone lattice discretizations from the universal R-matrix
International Nuclear Information System (INIS)
Meneghelli, C.
2015-04-01
Our goal is to develop a more general scheme for constructing integrable lattice regularisations of integrable quantum field theories. Considering the affine Toda theories as examples, we show how to construct such lattice regularisations using the representation theory of quantum affine algebras. This requires us to clarify in particular the relations between the light-cone approach to integrable lattice models and the representation theory of quantum affine algebras. Both are found to be related in a very natural way, suggesting a general scheme for the construction of generalised Baxter Q-operators. One of the main difficulties we need to deal with is coming from the infinite-dimensionality of the relevant families of representations. It is handled by means of suitable renormalisation prescriptions defining what may be called the modular double of quantum affine algebras. This framework allows us to give a representation-theoretic proof of finite-difference equations generalising the Baxter equation.
Del Favero, Marietta; Hinson, Janice M.
2007-01-01
The press for implementing technology based instructional delivery systems in community and technical colleges is well documented. Yet faculty face numerous challenges in integrating technology into instruction (AL-Bataineh & Brooks, 2003; Groves & Zemel, 2000; Khoury, 1997). Stimulating faculty ownership in technology, diffusion of technology use…
Strategy BMT Al-Ittihad Using Matrix IE, Matrix SWOT 8K, Matrix SPACE and Matrix TWOS
Directory of Open Access Journals (Sweden)
Nofrizal Nofrizal
2018-03-01
Full Text Available This research aims to formulate and select BMT Al-Ittihad Rumbai strategy to face the changing of business environment both from internal environment such as organization resources, finance, member and external business such as competitor, economy, politics and others. This research method used Analysis of EFAS, IFAS, IE Matrix, SWOT-8K Matrix, SPACE Matrix and TWOS Matrix. our hope from this research it can assist BMT Al-Ittihad in formulating and selecting strategies for the sustainability of BMT Al-Ittihad in the future. The sample in this research is using purposive sampling technique that is the manager and leader of BMT Al-IttihadRumbaiPekanbaru. The result of this research shows that the position of BMT Al-Ittihad using IE Matrix, SWOT-8K Matrix and SPACE Matrix is in growth position, stabilization and aggressive. The choice of strategy after using TWOS Matrix is market penetration, market development, vertical integration, horizontal integration, and stabilization (careful.
Shin, Sung-Ho; Ji, Sangyoon; Choi, Seiho; Pyo, Kyoung-Hee; Wan An, Byeong; Park, Jihun; Kim, Joohee; Kim, Ju-Young; Lee, Ki-Suk; Kwon, Soon-Yong; Heo, Jaeyeong; Park, Byong-Guk; Park, Jang-Ung
2017-03-31
Integrated electronic circuitries with pressure sensors have been extensively researched as a key component for emerging electronics applications such as electronic skins and health-monitoring devices. Although existing pressure sensors display high sensitivities, they can only be used for specific purposes due to the narrow range of detectable pressure (under tens of kPa) and the difficulty of forming highly integrated arrays. However, it is essential to develop tactile pressure sensors with a wide pressure range in order to use them for diverse application areas including medical diagnosis, robotics or automotive electronics. Here we report an unconventional approach for fabricating fully integrated active-matrix arrays of pressure-sensitive graphene transistors with air-dielectric layers simply formed by folding two opposing panels. Furthermore, this realizes a wide tactile pressure sensing range from 250 Pa to ∼3 MPa. Additionally, fabrication of pressure sensor arrays and transparent pressure sensors are demonstrated, suggesting their substantial promise as next-generation electronics.
Del Mercato, Loretta L; Passione, Laura Gioia; Izzo, Daniela; Rinaldi, Rosaria; Sannino, Alessandro; Gervaso, Francesca
2016-09-01
Three-dimensional (3D) porous scaffolds based on collagen are promising candidates for soft tissue engineering applications. The addition of stimuli-responsive carriers (nano- and microparticles) in the current approaches to tissue reconstruction and repair brings about novel challenges in the design and conception of carrier-integrated polymer scaffolds. In this study, a facile method was developed to functionalize 3D collagen porous scaffolds with biodegradable multilayer microcapsules. The effects of the capsule charge as well as the influence of the functionalization methods on the binding efficiency to the scaffolds were studied. It was found that the binding of cationic microcapsules was higher than that of anionic ones, and application of vacuum during scaffolds functionalization significantly hindered the attachment of the microcapsules to the collagen matrix. The physical properties of microcapsules-integrated scaffolds were compared to pristine scaffolds. The modified scaffolds showed swelling ratios, weight losses and mechanical properties similar to those of unmodified scaffolds. Finally, in vitro diffusional tests proved that the collagen scaffolds could stably retain the microcapsules over long incubation time in Tris-HCl buffer at 37°C without undergoing morphological changes, thus confirming their suitability for tissue engineering applications. The obtained results indicate that by tuning the charge of the microcapsules and by varying the fabrication conditions, collagen scaffolds patterned with high or low number of microcapsules can be obtained, and that the microcapsules-integrated scaffolds fully retain their original physical properties. Copyright © 2016 Elsevier Ltd. All rights reserved.
Ray, Sumanta; Maulik, Ujjwal
2016-12-20
Detecting perturbation in modular structure during HIV-1 disease progression is an important step to understand stage specific infection pattern of HIV-1 virus in human cell. In this article, we proposed a novel methodology on integration of multiple biological information to identify such disruption in human gene module during different stages of HIV-1 infection. We integrate three different biological information: gene expression information, protein-protein interaction information and gene ontology information in single gene meta-module, through non negative matrix factorization (NMF). As the identified metamodules inherit those information so, detecting perturbation of these, reflects the changes in expression pattern, in PPI structure and in functional similarity of genes during the infection progression. To integrate modules of different data sources into strong meta-modules, NMF based clustering is utilized here. Perturbation in meta-modular structure is identified by investigating the topological and intramodular properties and putting rank to those meta-modules using a rank aggregation algorithm. We have also analyzed the preservation structure of significant GO terms in which the human proteins of the meta-modules participate. Moreover, we have performed an analysis to show the change of coregulation pattern of identified transcription factors (TFs) over the HIV progression stages.
Energy Technology Data Exchange (ETDEWEB)
Shan, Hongzhan; Austin, Brian M.; De Jong, Wibe A.; Oliker, Leonid; Wright, Nicholas J.; Apra, Edoardo
2014-10-01
Attaining performance in the evaluation of two-electron repulsion integrals and constructing the Fock matrix is of considerable importance to the computational chemistry community. Due to its numerical complexity improving the performance behavior across a variety of leading supercomputing platforms is an increasing challenge due to the significant diversity in high-performance computing architectures. In this paper, we present our successful tuning methodology for these important numerical methods on the Cray XE6, the Cray XC30, the IBM BG/Q, as well as the Intel Xeon Phi. Our optimization schemes leverage key architectural features including vectorization and simultaneous multithreading, and results in speedups of up to 2.5x compared with the original implementation.
Cammarota, M; Huppes, V; Gaia, S; Degoulet, P
1998-01-01
The development of Health Information Systems is widely determined by the establishment of the underlying information models. An Object-Oriented Matrix Model (OOMM) is described which target is to facilitate the integration of the overall health system. The model is based on information modules named micro-databases that are structured in a three-dimensional network: planning, health structures and information systems. The modelling tool has been developed as a layer on top of a relational database system. A visual browser facilitates the development and maintenance of the information model. The modelling approach has been applied to the Brasilia University Hospital since 1991. The extension of the modelling approach to the Brasilia regional health system is considered.
Martínez-Delgado, Alejandra Anahí; Khandual, Sanghamitra; Villanueva-Rodríguez, Socorro Josefina
2017-06-15
Astaxanthin is a carotenoid pigment found in numerous organisms ranging from bacteria to algae, yeasts, plants, crustaceans and fish such as salmon. Technological importance of this pigment emerged from various studies demonstrating that it is a powerful antioxidant, even with higher activity than alpha-tocopherol and other carotenoids. It has been included in various pharmaceutical products because of several beneficial properties. By its nature, astaxanthin is susceptible to degradation and can undergo chemical changes during food processing. Therefore, different studies have focused on improving the stability of the carotenoid under conditions such as high temperatures, pressures and mechanical force, among others. In this review, common processes involved in food processing and their effect on the stability of astaxanthin, integrated into a food matrix are discussed. Moreover, preservation techniques such as microencapsulation, inclusion in emulsions, suspensions, liposomes, etc., that are being employed to maintain stability of the product are also reviewed. Copyright © 2016 Elsevier Ltd. All rights reserved.
Directory of Open Access Journals (Sweden)
Anja Schmidt
2018-02-01
Full Text Available The research and development of new materials such as particle-reinforced aluminum matrix composites (AMCs will only result in a successful innovation if these materials show significant advantages not only from a technological, but also from an economic point of view. Against this background, in the Collaborative Research Center SFB 692, the concept of an integrated technology, user, and market analysis and forecast has been developed as a means for assessing the technological and commercial potential of new materials in early life cycle stages. After briefly describing this concept, it is applied to AMCs and the potential field of manufacturing aircraft components. Results show not only technological advances, but also considerable economic potential—the latter one primarily resulting from the possible weight reduction being enabled by the increased yield strength of the new material.
A compact versatile matrix converter to integrate various energy resources to utility network
DEFF Research Database (Denmark)
Liu, Xiong; Loh, Poh Chiang; Wang, Peng
2011-01-01
for the connection of two three-phase AC sources or one threephase AC and three DC sources, which make it possible to integrate both DC and AC renewable sources in a single gridtied power electronics interface. The control and modulation schemes are proposed to extract the commanded current from the input AC....../DC sources to the network and to guarantee high quality DC/AC inputs and AC output current waveforms with unity power factors. The proposed modulation scheme for sinusoidal outputs has been mathematically proved. The simulation and experimental results for two applications are provided to validate...
Energy Technology Data Exchange (ETDEWEB)
Demming, Stefanie; Buettgenbach, Stephanus [Institute for Microtechnology (IMT), Technische Universitaet Braunschweig, Alte Salzdahlumer Strasse 203, 38124 Braunschweig (Germany); Hahn, Anne; Barcikowski, Stephan [Nanotechnology Department, Laser Zentrum Hannover e.V. (LZH), Hollerithallee 8, 30419 Hannover (Germany); Edlich, Astrid; Franco-Lara, Ezequiel; Krull, Rainer [Institute of Biochemical Engineering (IBVT), Technische Universitaet Braunschweig, Gaussstrasse 17, 38106 Braunschweig (Germany)
2010-04-15
The mergence of microfluidics and nanocomposite materials and their in situ structuring leads to a higher integration level within microsystems technology. Nanoparticles (Cu and Ag) produced via laser radiation were suspended in Poly(dimethylsiloxane) to permanently modify surface material. A microstructuring process was implemented which allows the incorporation of these nanomaterials globally or partially at defined locations within a microbioreactor (MBR) for the determination of their antiseptic and toxic effects on the growth of biomass. Partially structured PDMS with nanoparticle-PDMS composite. (Abstract Copyright [2010], Wiley Periodicals, Inc.)
Energy Technology Data Exchange (ETDEWEB)
Ferraris, John P. [Univ. of Texas-Dallas, Richardson, TX (United States). Dept. of Chemistry
2013-09-30
Nanoparticles of zeolitic imidazolate frameworks and other related hybrid materials were prepared by modifying published synthesis procedures by introducing bases, changing stoichiometric ratios, or adjusting reaction conditions. These materials were stable at temperatures >300 °C and were compatible with the polymer matrices used to prepare mixed- matrix membranes (MMMs). MMMs tested at 300 °C exhibited a >30 fold increase in permeability, compared to those measured at 35 °C, while maintaining H_{2}/CO_{2} selectivity. Measurements at high pressure (up to 30 atm) and high temperature (up to 300 °C) resulted in an increase in gas flux across the membrane with retention of selectivity. No variations in permeability were observed at high pressures at either 35 or 300 °C. CO_{2}-induced plasticization was not observed for Matrimid®, VTEC, and PBI polymers or their MMMs at 30 atm and 300 °C. Membrane surface modification by cross-linking with ethanol diamine resulted in an increase in H_{2}/CO_{2} selectivity at 35 °C. Spectrometric analysis showed that the cross-linking was effective to temperatures <150 °C. At higher temperatures, the cross-linked membranes exhibit a H_{2}/CO_{2} selectivity similar to the uncross-linked polymer. Performance of the polybenzimidazole (PBI) hollow fibers prepared at Santa Fe Science and Technology (SFST, Inc.) showed increased flux and selectivity at 300 °C, which is comparable to a flat PBI membrane. A water-gas shift reactor has been built and currently being optimized for testing under DOE conditions.
International Nuclear Information System (INIS)
Park, Joo Hyun
1999-02-01
When transitions occur in large systems such as nuclear power plants (NPPs) or industrial process plants, it is often difficult to diagnose them. Various computer-based operator-aiding systems have been developed in order to help operators diagnose the transitions of the plants. In procedures for developing knowledge base system like operator-aiding systems, the knowledge acquisition and the knowledge base verification are core activities. This dissertation describes a knowledge acquisition method and a knowledge base verification method for developing high-integrity knowledge base system of NPP expert systems. The knowledge acquisition is one of the most difficult and time-consuming activities in developing knowledge base systems. There are two kinds of knowledge acquisition methods in view of knowledge sources. One is an acquisition method from human expert. This method, however, is not adequate to acquire the knowledge of NPP expert systems because the number of experts is not sufficient. In this work, we propose a novel knowledge acquisition method through documents analysis. The knowledge base can be built correctly, rapidly, and partially automatically through this method. This method is especially useful when it is difficult to find domain experts. Reliability of knowledge base systems depends on the quality of their knowledge base. Petri Net has been used to verify knowledge bases due to their formal outputs. The methods using Petri Net however are difficult to apply to large and complex knowledge bases because the Net becomes very large and complex. Also, with Petri Net, it is difficult to find proper input patterns that make anomalies occur. In order to overcome this difficulty, in this work, the anomaly candidates detection methods are developed based on Extended CPN (ECPN) matrix analysis. This work also defines the backward simulation of CPN to find compact input patterns for anomaly detection, which starts simulation from the anomaly candidates
DEFF Research Database (Denmark)
Hounyo, Ulrich
to a gneral class of estimators of integrated covolatility. We then show the first-order asymptotic validity of this method in the multivariate context with a potential presence of jumps, dependent microsturcture noise, irregularly spaced and non-synchronous data. Due to our focus on non...... covariance estimator. As an application of our results, we also consider the bootstrap for regression coefficients. We show that the wild blocks of bootstrap, appropriately centered, is able to mimic both the dependence and heterogeneity of the scores, thus justifying the construction of bootstrap percentile...... intervals as well as variance estimates in this context. This contrasts with the traditional pairs bootstrap which is not able to mimic the score heterogeneity even in the simple case where no microsturcture noise is present. Our Monte Carlo simulations show that the wild blocks of blocks bootstrap improves...
Peng, G.; Austin, M.
2017-12-01
Identification and prioritization of targeted user community needs are not always considered until after data has been created and archived. Gaps in data curation and documentation in the data production and delivery phases limit data's broad utility specifically for decision makers. Expert understanding and knowledge of a particular dataset is often required as a part of the data and metadata curation process to establish the credibility of the data and support informed decision-making. To enhance curation practices, content from NOAA's Observing System Integrated Assessment (NOSIA) Value Tree, NOAA's Data Catalog/Digital Object Identifier (DOI) projects (collection-level metadata) have been integrated with Data/Stewardship Maturity Matrices (data and stewardship quality information) focused on assessment of user community needs. This results in user focused evidence based decision making tools created by NOAA's National Environmental Satellite, Data, and Information Service (NESDIS) through identification and assessment of data content gaps related to scientific knowledge and application to key areas of societal benefit. Through enabling user need feedback from the beginning of data creation through archive allows users to determine the quality and value of data that is fit for purpose. Data gap assessment and prioritization are presented in a user-friendly way using the data stewardship maturity matrices as measurement of data management quality. These decision maker tools encourages data producers and data providers/stewards to consider users' needs prior to data creation and dissemination resulting in user driven data requirements increasing return on investment. A use case focused on need for NOAA observations linked societal benefit will be used to demonstrate the value of these tools.
Directory of Open Access Journals (Sweden)
Michael Scholz
2016-05-01
Full Text Available AIM Data Services as a virtual facility provides virtual 3D reference tracks for simulation applications in the domain of automotive and railway systems. It offers tools for management and analysis of experiment data and a platform for survey and processing of vehicle data in the public transport domain. Collected spatial data is bundled in a database cluster and published through common web mapping interfaces.
Chen, Chao; Raghunathan, Shreyas B; Yu, Zili; Shabanimotlagh, Maysam; Chen, Zhao; Chang, Zu-yao; Blaak, Sandra; Prins, Christian; Ponte, Jacco; Noothout, Emile; Vos, Hendrik J; Bosch, Johan G; Verweij, Martin D; de Jong, Nico; Pertijs, Michiel A P
2016-01-01
This paper presents the design, fabrication, and experimental evaluation of a prototype lead zirconium titanate (PZT) matrix transducer with an integrated receive ASIC, as a proof of concept for a miniature three-dimensional (3-D) transesophageal echocardiography (TEE) probe. It consists of an array of 9 ×12 piezoelectric elements mounted on the ASIC via an integration scheme that involves direct electrical connections between a bond-pad array on the ASIC and the transducer elements. The ASIC addresses the critical challenge of reducing cable count, and includes front-end amplifiers with adjustable gains and micro-beamformer circuits that locally process and combine echo signals received by the elements of each 3 ×3 subarray. Thus, an order-of-magnitude reduction in the number of receive channels is achieved. Dedicated circuit techniques are employed to meet the strict space and power constraints of TEE probes. The ASIC has been fabricated in a standard 0.18-μm CMOS process and consumes only 0.44 mW/channel. The prototype has been acoustically characterized in a water tank. The ASIC allows the array to be presteered across ±37° while achieving an overall dynamic range of 77 dB. Both the measured characteristics of the individual transducer elements and the performance of the ASIC are in good agreement with expectations, demonstrating the effectiveness of the proposed techniques.
Energy Technology Data Exchange (ETDEWEB)
Jha, Shantenu [Rutgers Univ., New Brunswick, NJ (United States)
2017-01-31
Many important advances in science and engineering are due to large-scale distributed computing. Notwithstanding this reliance, we are still learning how to design and deploy large-scale production Distributed Computing Infrastructures (DCI). The AIMES project was conceived against this backdrop, following on the heels of a comprehensive survey of scienti c distributed applications [1]. The survey established, arguably for the rst time, the relationship between infrastructure and scienti c distributed applications. It examined well known contributors to the complexity associated with infrastructure, such as inconsistent internal and external interfaces, and demonstrated the correlation with application brittleness. It discussed how infrastructure complexity reinforces the challenges inherent in developing distributed applications.
A matrix integral solution to two-dimensional Wp-gravity
International Nuclear Information System (INIS)
Adler, M.; Moerbeke, P. van; Louvain Univ., Louvain-la-Neuve
1992-01-01
The p th Gel'fand-Dickey equation and the string equation [L.P.] = 1 have a common solution τ experessible in terms of an integral over n x n Hermitean matrices (for large n). the integrand being a perturbation of a Gaussian. generalizing Kontsevich's inegral beyond the KdV-case; it is equivalent to showing that τ is a vacuum vector for a Q p + -algebra, generated from the coefficients of the vertex operator. This connectionis established via a quadratic identity involving the wave function and the vertex operator, which is disguised differential version of the Fay identity. The latter is also the key to the spectral theory for the two compatible symplectic structures of KdV in terms of the stress-energy tensor associated with the Virasoro algebra. Given a differential operator L=D p +q 2 (t)D p-2 +...+q p (t), with D=d/dx, t=(t 1 , t 2 , t 3 , ...), x=t 1 , consider the deformation equations dL/dt n =[(L n/p ) + , L] n=1, 2, ..., n≠0(mod p) (p-reduced KP-equation) of L, for which there exists a differential operator P (possibly of infinite order) such that [L, P]=1 (string equation). In this note, we give a complete solution to this problem. (orig./HSI)
DEFF Research Database (Denmark)
Offersen, Sara Marie Hebsgaard
that the Danes are encouraged to be alert to still earlier and vaguer bodily signs of potential cancer and seek care ‘in time’. With biomedical constructions such as ‘cancer awareness’ and ‘alarm symptoms of cancer’ and the retrospectively oriented definition of life before symptoms-based healthcare seeking...... and articulation of bodily sensations, and how decisions about healthcare seeking are established in this context. This dissertation aims to explore these matters from the perspective of the Danish middle class, mainly focusing on how sensations are ascribed meaning as symptoms and how they are evoked...... on a continuum between what is locally considered ordinary and extraordinary. Overall, the dissertation argues that inquiries into morality and potentiality provide valuable insights into healthcare seeking practices and the making and management of symptoms in everyday life. The dissertation is based on 18...
Directory of Open Access Journals (Sweden)
Nik G Wiman
Full Text Available Temperature-dependent fecundity and survival data was integrated into a matrix population model to describe relative Drosophila suzukii Matsumura (Diptera: Drosophilidae population increase and age structure based on environmental conditions. This novel modification of the classic Leslie matrix population model is presented as a way to examine how insect populations interact with the environment, and has application as a predictor of population density. For D. suzukii, we examined model implications for pest pressure on crops. As case studies, we examined model predictions in three small fruit production regions in the United States (US and one in Italy. These production regions have distinctly different climates. In general, patterns of adult D. suzukii trap activity broadly mimicked seasonal population levels predicted by the model using only temperature data. Age structure of estimated populations suggest that trap and fruit infestation data are of limited value and are insufficient for model validation. Thus, we suggest alternative experiments for validation. The model is advantageous in that it provides stage-specific population estimation, which can potentially guide management strategies and provide unique opportunities to simulate stage-specific management effects such as insecticide applications or the effect of biological control on a specific life-stage. The two factors that drive initiation of the model are suitable temperatures (biofix and availability of a suitable host medium (fruit. Although there are many factors affecting population dynamics of D. suzukii in the field, temperature-dependent survival and reproduction are believed to be the main drivers for D. suzukii populations.
Nakazawa, Toru
2015-03-01
-independent factors, as well as our investigation of ways to improve the clinical evaluation of the disease. Our research was prompted by the multifactorial nature of glaucoma. There is a high degree of variability in the pattern and speed of the progression of visual field defects in individual patients, presenting a major obstacle for successful clinical trials. To overcome this, we classified the eyes of glaucoma patients into 4 types, corresponding to the 4 patterns of glaucomatous optic nerve head morphology described: by Nicolela et al. and then tested the validity of this method by assessing the uniformity of clinical features in each group. We found that in normal tension glaucoma (NTG) eyes, each disc morphology group had a characteristic location in which the loss of circumpapillary retinal nerve fiber layer thickness (cpRNFLT; measured with optical coherence tomography: OCT) was most likely to occur. Furthermore, the incidence of reductions in visual acuity differed between the groups, as did the speed of visual field loss, the distribution of defective visual field test points, and the location of test points that were most susceptible to progressive damage, measured by Humphrey static perimetry. These results indicate that Nicolela's method of classifying eyes with glaucoma was able to overcome the difficulties caused by the diverse nature of the disease, at least to a certain extent. Building on these findings, we then set out to identify sectors of the visual field that correspond to the distribution of retinal nerve fibers, with the aim of detecting glaucoma progression with improved sensitivity. We first mapped the statistical correlation between visual field test points and cpRNFLT in each temporal clock-hour sector (from 6 to 12 o'clock), using OCT data from NTG patients. The resulting series of maps allowed us to identify areas containing visual field test points that were prone to be affected together as a group. We also used a similar method to identify visual
Benhalouche, Fatima Zohra; Karoui, Moussa Sofiane; Deville, Yannick; Ouamri, Abdelaziz
2015-10-01
In this paper, a new Spectral-Unmixing-based approach, using Nonnegative Matrix Factorization (NMF), is proposed to locally multi-sharpen hyperspectral data by integrating a Digital Surface Model (DSM) obtained from LIDAR data. In this new approach, the nature of the local mixing model is detected by using the local variance of the object elevations. The hyper/multispectral images are explored using small zones. In each zone, the variance of the object elevations is calculated from the DSM data in this zone. This variance is compared to a threshold value and the adequate linear/linearquadratic spectral unmixing technique is used in the considered zone to independently unmix hyperspectral and multispectral data, using an adequate linear/linear-quadratic NMF-based approach. The obtained spectral and spatial information thus respectively extracted from the hyper/multispectral images are then recombined in the considered zone, according to the selected mixing model. Experiments based on synthetic hyper/multispectral data are carried out to evaluate the performance of the proposed multi-sharpening approach and literature linear/linear-quadratic approaches used on the whole hyper/multispectral data. In these experiments, real DSM data are used to generate synthetic data containing linear and linear-quadratic mixed pixel zones. The DSM data are also used for locally detecting the nature of the mixing model in the proposed approach. Globally, the proposed approach yields good spatial and spectral fidelities for the multi-sharpened data and significantly outperforms the used literature methods.
Zhao, Ying; Song, Kaishan; Shang, Yingxin; Shao, Tiantian; Wen, Zhidan; Lv, Lili
2017-08-01
The spatial characteristics of fluorescent dissolved organic matter (FDOM) components in river waters in China were first examined by excitation-emission matrix spectra and fluorescence regional integration (FRI) with the data collected during September to November between 2013 and 2015. One tyrosine-like (R1), one tryptophan-like (R2), one fulvic-like (R3), one microbial protein-like (R4), and one humic-like (R5) components have been identified by FRI method. Principal component analysis (PCA) was conducted to assess variations in the five FDOM components (FRί (ί = 1, 2, 3, 4, and 5)) and the humification index for all 194 river water samples. The average fluorescence intensities of the five fluorescent components and the total fluorescence intensities FSUM differed under spatial variation among the seven major river basins (Songhua, Liao, Hai, Yellow and Huai, Yangtze, Pearl, and Inflow Rivers) in China. When all the river water samples were pooled together, the fulvic-like FR3 and the humic-like FR5 showed a strong positive linear relationship (R2 = 0.90, n = 194), indicating that the two allochthonous FDOM components R3 and R5 may originate from similar sources. There is a moderate strong positive correlation between the tryptophan-like FR2 and the microbial protein-like FR4 (R2 = 0.71, n = 194), suggesting that parts of two autochthonous FDOM components R2 and R4 are likely from some common sources. However, the total allochthonous substance FR(3+5) and the total autochthonous substances FR(1+2+4) exhibited a weak correlation (R2 = 0.40, n = 194). Significant positive linear relationships between FR3 (R2 = 0.69, n = 194), FR5 (R2 = 0.79, n = 194), and chromophoric DOM (CDOM) absorption coefficient a(254) were observed, which demonstrated that the CDOM absorption was dominated by the allochthonous FDOM components R3 and R5.
Zhan, Xingzhi
2002-01-01
The main purpose of this monograph is to report on recent developments in the field of matrix inequalities, with emphasis on useful techniques and ingenious ideas. Among other results this book contains the affirmative solutions of eight conjectures. Many theorems unify or sharpen previous inequalities. The author's aim is to streamline the ideas in the literature. The book can be read by research workers, graduate students and advanced undergraduates.
DEFF Research Database (Denmark)
Ågren, Magnus S.; Andersen, Thomas L.; Andersen, Line
2011-01-01
Increased matrix metalloproteinase (MMP) activity has been implicated in the pathogenesis of colorectal anastomotic leakage. Tumor necrosis factor-a (TNF-a) induces MMPs and may influence anastomosis repair....
International Nuclear Information System (INIS)
Saakyan, D.B.; Shagoyan, R.M.
1992-01-01
Matrix models of strings have recently been studied intensively, especially in connection with the possibility of calculating nonperturbative effects (in the sense of expanding in the genera). Here, a one-matrix model with quartic interaction is considered. Equations are obtained for the contributions of diagrams with surface genus k and with M sites. The distributions of the contributions of the diagrams of order M over the genera k are studied numerically for orders up to M = 16
Indian Academy of Sciences (India)
Much of linear algebra is devoted to reducing a matrix (via similarity or unitary similarity) to another that has lots of zeros. The simplest such theorem is the Schur triangularization theorem. This says that every matrix is unitarily similar to an upper triangular matrix. Our aim here is to show that though it is very easy to prove it ...
Extended biorthogonal matrix polynomials
Directory of Open Access Journals (Sweden)
Ayman Shehata
2017-01-01
Full Text Available The pair of biorthogonal matrix polynomials for commutative matrices were first introduced by Varma and Tasdelen in [22]. The main aim of this paper is to extend the properties of the pair of biorthogonal matrix polynomials of Varma and Tasdelen and certain generating matrix functions, finite series, some matrix recurrence relations, several important properties of matrix differential recurrence relations, biorthogonality relations and matrix differential equation for the pair of biorthogonal matrix polynomials J(A,B n (x, k and K(A,B n (x, k are discussed. For the matrix polynomials J(A,B n (x, k, various families of bilinear and bilateral generating matrix functions are constructed in the sequel.
Klein, Sabrina; Zimmermann, Stefan; Köhler, Christine; Mischnik, Alexander; Alle, Werner; Bode, Konrad A
2012-03-01
Sepsis is a major cause of mortality in hospitalized patients worldwide, with lethality rates ranging from 30 to 70 %. Sepsis is caused by a variety of different pathogens, and rapid diagnosis is of outstanding importance, as early and adequate antimicrobial therapy correlates with positive clinical outcome. In recent years, matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry (MS) fingerprinting has become a powerful tool in microbiological diagnostics. The direct identification of micro-organisms in a positive blood culture by MALDI-TOF MS can shorten the diagnostic procedure significantly. Therefore, the aim of the present study was to evaluate whether identification rates could be improved by using the new Sepsityper kit from Bruker Daltonics for direct isolation and identification of bacteria from positive blood cultures by MALDI-TOF MS compared with the use of conventional separator gel columns, and to integrate the MALDI-TOF MS-based identification method into the routine course of blood culture diagnostics in the setting of a microbiological laboratory at a university hospital in Germany. The identification of Gram-negative bacteria by MALDI-TOF MS was significantly better using the Sepsityper kit compared with a separator gel tube-based method (99 and 68 % correct identification, respectively). For Gram-positive bacteria, only 73 % were correctly identified by MALDI-TOF with the Sepsityper kit and 59 % with the separator gel tube assay. A major problem of both methods was the poor identification of Gram-positive grape-like clustered cocci. As differentiation of Staphylococcus aureus from coagulase-negative staphylococci is of clinical importance, a PCR was additionally established that was capable of identifying S. aureus directly from positive blood cultures, thus closing this diagnostic gap. Another benefit of the PCR approach is the possibility of directly detecting the genes responsible for meticillin
CERN. Geneva
2016-01-01
In this talk I will describe recent work aiming to reinvigorate the 50 year old S-matrix program, which aims to constrain scattering of massive particles non-perturbatively. I will begin by considering quantum fields in anti-de Sitter space and show that one can extract information about the S-matrix by considering correlators in conformally invariant theories. The latter can be studied with "bootstrap" techniques, which allow us to constrain the S-matrix. In particular, in 1+1D one obtains bounds which are saturated by known integrable models. I will also show that it is also possible to directly constrain the S-matrix, without using the CFT crutch, by using crossing symmetry and unitarity. This alternative method is simpler and gives results in agreement with the previous approach. Both techniques are generalizable to higher dimensions.
Energy Technology Data Exchange (ETDEWEB)
Popel, A.J., E-mail: apopel@cantab.net [Department of Earth Sciences, University of Cambridge, Downing Street, Cambridge, CB2 3EQ (United Kingdom); Department of Materials, Imperial College London, London, SW7 2AZ (United Kingdom); Le Solliec, S.; Lampronti, G.I.; Day, J. [Department of Earth Sciences, University of Cambridge, Downing Street, Cambridge, CB2 3EQ (United Kingdom); Petrov, P.K. [Department of Materials and London Centre for Nanotechnology, Imperial College London, London, SW7 2AZ (United Kingdom); Farnan, I. [Department of Earth Sciences, University of Cambridge, Downing Street, Cambridge, CB2 3EQ (United Kingdom)
2017-02-15
This work considers the effect of fission fragment damage on the structural integrity and dissolution of the CeO{sub 2} matrix in water, as a simulant for the UO{sub 2} matrix of spent nuclear fuel. For this purpose, thin films of CeO{sub 2} on Si substrates were produced and irradiated by 92 MeV {sup 129}Xe{sup 23+} ions to a fluence of 4.8 × 10{sup 15} ions/cm{sup 2} to simulate fission damage that occurs within nuclear fuels along with bulk CeO{sub 2} samples. The irradiated and unirradiated samples were characterised and a static batch dissolution experiment was conducted to study the effect of the induced irradiation damage on dissolution of the CeO{sub 2} matrix. Complex restructuring took place in the irradiated films and the irradiated samples showed an increase in the amount of dissolved cerium, as compared to the corresponding unirradiated samples. Secondary phases were also observed on the surface of the irradiated CeO{sub 2} films after the dissolution experiment. - Highlights: • Ion irradiation induced microstructural rearrangements in CeO{sub 2} thin films. • Ion irradiation reduced aqueous durability of bulk and thin film CeO{sub 2} samples. • Secondary phases observed from dissolution of irradiated CeO{sub 2} films in di-water.
International Nuclear Information System (INIS)
Yamada, Masahiro; Kato, Eiji; Sakurai, Kaoru; Yamamoto, Akiko
2016-01-01
The acquisition of substantial dermal sealing determines the prognosis of percutaneous titanium-based medical devices or prostheses. A nano-topographic titanium surface with ordered nano-spikes and pores has been shown to induce periodontal-like connective tissue attachment and activate gingival fibroblastic functions. This in vitro study aimed to determine whether an alkali-heat (AH) treatment-created nano-topographic titanium surface could enhance human dermal fibroblastic functions and binding strength to the deposited collagen on the titanium surface. The surface topographies of commercially pure titanium machined discs exposed to two different AH treatments were evaluated. Human dermal fibroblastic cultures grown on the discs were evaluated in terms of cellular morphology, proliferation, extracellular matrix (ECM) and proinflammatory cytokine synthesis, and physicochemical binding strength of surface-deposited collagen. An isotropically-patterned, shaggy nano-topography with a sponge-like inner network and numerous well-organized, anisotropically-patterned fine nano-spikes and pores were observed on each nano-topographic surface type via scanning electron microscopy. In contrast to the typical spindle-shaped cells on the machined surfaces, the isotropically- and anisotropically-patterned nano-topographic titanium surfaces had small circular/angular cells containing contractile ring-like structures and elongated, multi-shaped cells with a developed cytoskeletal network and multiple filopodia and lamellipodia, respectively. These nano-topographic surfaces enhanced dermal-related ECM synthesis at both the protein and gene levels, without proinflammatory cytokine synthesis or reduced proliferative activity. Deposited collagen fibers were included in these surfaces and sufficiently bound to the nano-topographies to resist the physical, enzymatic and chemical detachment treatments, in contrast to machined surfaces. Well-organized, isotropically
Blumbach, K.; Bastiaansen-Jenniskens, Y.M.; Groot, J. de; Paulsson, M.; Osch, G.J.V.M. van; Zaucke, F.
2009-01-01
Objective. Defects in the assembly and composition of cartilage extracellular matrix are likely to result in impaired matrix integrity and increased susceptibility to cartilage degeneration. The aim of this study was to determine the functional interaction of the collagen fibril-associated proteins
International Nuclear Information System (INIS)
Mannioui, Abdelkrim; Nelson, Elisabeth; Schiffer, Cecile
2005-01-01
We analyzed the role of human immunodeficiency virus (HIV)-1 matrix protein (MA) during the virus replication afferent phase. Single-round infection of H9 T lymphocytes showed that the combined mutation of MA Lys residues 26-27 in MA reported nuclear localization signal (NLS)-1 [Haffar, O.K., Popov, S., Dubrovsky, L., Agostini, I., Tang, H., Pushkarsky, T., Nadler, S.G., Bukrinsky, M., 2000. Two nuclear localization signals in the HIV-1 matrix protein regulate nuclear import of the HIV-1 pre-integration complex. J. Mol. Biol. 299 (2): 359-368] impaired infectivity, abrogated 2-LTR-circle formation and significantly reduced integration. However, the mutation did not affect viral DNA docking to chromatin in either interphasic or mitotic cells, indicating that MA N-terminal basic domain should not represent a major determinant of HIV-1 nuclear import in T lymphocytes. These data point to a previously unreported role of MA in the late, post-chromatin-binding, afferent phase of HIV-1 replication cycle
A matrix of social accounting for Asturias
Directory of Open Access Journals (Sweden)
Margarita Argüelles
2003-01-01
Full Text Available A Social Accounting Matrix is an integrated system of accounts that presents in a double-entry table all the transactions made in an economy among productive sectors, production factors, institutional sectors and the rest of the world. In comparison with an Input-Output Table, it offers a greater deal of information and shows completely the circular process of income, captivating more precisely the effects of exogenous changes. One of the main profits of a Social Accounting Matrix is to serve as a database for the development and application of a computable general equilibrium model. This is, in fact, the aim pursued with the elaboration of the Social Accounting Matrix for the Asturian economy presented here. This Matrix has been constructed with data from the 1995 Regional Accounts of Asturias, and its structure has been adapted to its future use as a database for a computable general equilibrium model of this regional economy.
International Nuclear Information System (INIS)
Sandhas, W.
1978-01-01
In the N-body problem mappings between channel states and scattering states are studied. It is shown in particular that the (2sup(N-1)-1) two-fragment MOELLER operators introduced on the whole Hilbert space are sufficient to provide all multi-fragment scattering states. Hence, each of these states is uniquely determined by (2sup(N-1)-1) Lippmann-Schwinger (LS) equations. Rewriting every set of LS equations as one matrix equation, current few-body approaches are incorporated in a rather natural way. The typical uniqueness questions of such coupled systems are discussed, and it is shown that Faddeev-type couplings lead to unique equations for arbitrary N. (author)
International Nuclear Information System (INIS)
Sandhas, W.
1978-04-01
In the N-body problem mappings between channel states and scattering states are studied. It is shown in particular that the (2sup(N-1)-1) two-fragment Moeller operators introduced on the whole Hilbert space are sufficient to provide all multifragment scattering states. Hence, each of these states is uniquly determined by (2sup(N-1)-1) Lippmann-Schwinger (LS) equations. Rewriting every set of LS equations as one matrix equation, current few-body approaches are incorporated in a rather natural way. The typical uniqueness questions of such coupled systems are discussed, and it si shown that Faddeev-type couplings lead to unique equations for arbitrary N. (orig.) [de
ENTERPRISE RESTRUCTURING AIM AND TYPES
Directory of Open Access Journals (Sweden)
S. P. Baranenko
2011-01-01
Full Text Available Enterprise restructuring is aimed at adapting it to market conditions and improving its competitiveness through selection of most effective model of using material, technical, technological, organizational, commercial, economical, financial, tax-related and other resources with due account of the demand. Restructuring classification signs and types as well as restructuring aims specific for industrial enterprises are provided for.
Directory of Open Access Journals (Sweden)
Saeid Peirow
2016-02-01
Full Text Available Today, the internal service quality as one of the most important factors affecting the recruitment and retention of staff is considered. The present study sought to examine the internal service quality of Yazd Regional Electric, finally, select appropriate strategies to improve the quality of local services in the organization. The application of this study is base on survey method.Data were collected from questionnaires to evaluate the 26 components of internal service quality of Yazd Regional Electric, has been used. Research community is the staff of the organisation.Also, the sample size, the initial questionnaire was distributed according to Cochran's formula is calculated.In order to analyze research data, the model is important - satisfaction and performance control matrix to identify those components that are used need to be improved.Also, in order to prioritize measures to improve employee satisfaction index is used. Data analysis using above tools show, 8 criteria are in improvment area. So, these criteria are prioritized with ESI.
International Nuclear Information System (INIS)
Habershon, Scott
2013-01-01
We introduce a new approach for calculating quantum time-correlation functions and time-dependent expectation values in many-body thermal systems; both electronically adiabatic and non-adiabatic cases can be treated. Our approach uses a path integral simulation to sample an initial thermal density matrix; subsequent evolution of this density matrix is equivalent to solution of the time-dependent Schrödinger equation, which we perform using a linear expansion of Gaussian wavepacket basis functions which evolve according to simple classical-like trajectories. Overall, this methodology represents a formally exact approach for calculating time-dependent quantum properties; by introducing approximations into both the imaginary-time and real-time propagations, this approach can be adapted for complex many-particle systems interacting through arbitrary potentials. We demonstrate this method for the spin Boson model, where we find good agreement with numerically exact calculations. We also discuss future directions of improvement for our approach with a view to improving accuracy and efficiency
Habershon, Scott
2013-09-14
We introduce a new approach for calculating quantum time-correlation functions and time-dependent expectation values in many-body thermal systems; both electronically adiabatic and non-adiabatic cases can be treated. Our approach uses a path integral simulation to sample an initial thermal density matrix; subsequent evolution of this density matrix is equivalent to solution of the time-dependent Schrödinger equation, which we perform using a linear expansion of Gaussian wavepacket basis functions which evolve according to simple classical-like trajectories. Overall, this methodology represents a formally exact approach for calculating time-dependent quantum properties; by introducing approximations into both the imaginary-time and real-time propagations, this approach can be adapted for complex many-particle systems interacting through arbitrary potentials. We demonstrate this method for the spin Boson model, where we find good agreement with numerically exact calculations. We also discuss future directions of improvement for our approach with a view to improving accuracy and efficiency.
Potochnik, Angela
2015-10-01
There is increasing attention to the centrality of idealization in science. One common view is that models and other idealized representations are important to science, but that they fall short in one or more ways. On this view, there must be an intermediary step between idealized representation and the traditional aims of science, including truth, explanation, and prediction. Here I develop an alternative interpretation of the relationship between idealized representation and the aims of science. I suggest that continuing, widespread idealization calls into question the idea that science aims for truth. If instead science aims to produce understanding, this would enable idealizations to directly contribute to science's epistemic success. I also use the fact of widespread idealization to motivate the idea that science's wide variety aims, epistemic and non-epistemic, are best served by different kinds of scientific products. Finally, I show how these diverse aims—most rather distant from truth—result in the expanded influence of social values on science. Copyright © 2015 Elsevier Ltd. All rights reserved.
Franklin, Joel N
2003-01-01
Mathematically rigorous introduction covers vector and matrix norms, the condition-number of a matrix, positive and irreducible matrices, much more. Only elementary algebra and calculus required. Includes problem-solving exercises. 1968 edition.
... out of your control, you can make positive lifestyle changes to lose weight and to maintain a healthy weight. These include a healthy eating plan and being more physically active. Take the Challenge When it comes to aiming for a healthy ...
Aims, assessments and workplace needs
Black, Paul
1997-03-01
This paper attempts to consider the aims that undergraduate physics degree courses actually reflect and serve in the light of the employment patterns of graduates and of the expressed needs of employers. Calling on evidence mainly from the UK, it reviews analyses of what degree examinations actually test, and goes on to quote criticisms of their courses and radical proposals to change them adopted by the senior physics professors in the UK. The discussion is then broadened by discussion of evidence, about the employment of graduates and about the priorities that some industrialists now give in the qualities that they look for when recruiting new graduates. The evidence leads to a view that radical changes are needed, both in courses and examinations, and that there is a need for university departments to work more closely with employers in re-formulating the aims and priorities in their teaching.
Choi, Hyeon-Gyu; Son, Moon; Choi, Heechul
2017-10-01
Thin-film composite mixed matrix membrane (TFC MMM) with functionalized carbon nanotube (fCNT) blended in polyethersulfone (PES) support layer was synthesized via interfacial polymerization and phase inversion. This membrane was firstly tested in lab-scale integrating seawater desalination and wastewater reclamation forward osmosis (FO) process. Water flux of TFC MMM was increased by 72% compared to that of TFC membrane due to enhanced hydrophilicity. Although TFC MMM showed lower water flux than TFC commercial membrane, enhanced reverse salt flux selectivity (RSFS) of TFC MMM was observed compared to TFC membrane (15% higher) and TFC commercial membrane (4% higher), representing membrane permselectivity. Under effluent organic matter (EfOM) fouling test, 16% less normalized flux decline of TFC MMM was observed compared to TFC membrane. There was 8% less decline of TFC MMM compared to TFC commercial membrane due to fCNT effect on repulsive foulant-membrane interaction enhancement, caused by negatively charged membrane surface. After 10 min physical cleaning, TFC MMM displayed higher recovered normalized flux than TFC membrane (6%) and TFC commercial membrane (4%); this was also supported by visualized characterization of fouling layer. This study presents application of TFC MMM to integrated seawater desalination and wastewater reclamation FO process for the first time. It can be concluded that EfOM fouling of TFC MMM was suppressed due to repulsive foulant-membrane interaction. Copyright © 2017 Elsevier Ltd. All rights reserved.
International Nuclear Information System (INIS)
Saddi, M.B.; Singh, Bhajan; Sandhu, B.S.
2008-01-01
The collision integral cross-sections of double-photon Compton process are measured experimentally for 662 keV incident gamma photons. The measurements are successfully carried out using a single gamma ray detector, and do not require the complicated slow-fast coincidence technique used till now for observing this higher order quantum electrodynamics (QED) process. The energy spectra of one of the two final photons, originating in this process, in direction of the gamma ray detector are observed as a long tail to the single-photon Compton line on lower side of the full energy peak in the observed spectra. An inverse response matrix converts the observed pulse-height distribution of a NaI(Tl) scintillation detector to a true photon spectrum. This also results in extraction of events originating from double-photon Compton interactions. The present measured values of collision integral cross-section, although of same magnitude, deviate from the corresponding values obtained from the theory. In view of the magnitude of deviations, in addition to small value of probability of occurrence of this process, the agreement of measured values with theory is reasonably acceptable
Directory of Open Access Journals (Sweden)
Seyed Sina Sebtahmadi
2016-11-01
Full Text Available A rotational d-q current control scheme based on a Particle Swarm Optimization- Proportional-Integral (PSO-PI controller, is used to drive an induction motor (IM through an Ultra Sparse Z-source Matrix Converter (USZSMC. To minimize the overall size of the system, the lowest feasible values of Z-source elements are calculated by considering the both timing and aspects of the circuit. A meta-heuristic method is integrated to the control system in order to find optimal coefficient values in a single multimodal problem. Henceforth, the effect of all coefficients in minimizing the total harmonic distortion (THD and balancing the stator current are considered simultaneously. Through changing the reference point of magnitude or frequency, the modulation index can be automatically adjusted and respond to changes without heavy computational cost. The focus of this research is on a reliable and lightweight system with low computational resources. The proposed scheme is validated through both simulation and experimental results.
Directory of Open Access Journals (Sweden)
Rupak Dua
Full Text Available We investigated the effectiveness of integrating tissue engineered cartilage derived from human bone marrow derived stem cells (HBMSCs to healthy as well as osteoarthritic cartilage mimics using hydroxyapatite (HA nanoparticles immersed within a hydrogel substrate. Healthy and diseased engineered cartilage from human chondrocytes (cultured in agar gels were integrated with human bone marrow stem cell (HBMSC-derived cartilaginous engineered matrix with and without HA, and evaluated after 28 days of growth. HBMSCs were seeded within photopolymerizable poly (ethylene glycol diacrylate (PEGDA hydrogels. In addition, we also conducted a preliminary in vivo evaluation of cartilage repair in rabbit knee chondral defects treated with subchondral bone microfracture and cell-free PEGDA with and without HA. Under in vitro conditions, the interfacial shear strength between tissue engineered cartilage derived from HBMSCs and osteoarthritic chondrocytes was significantly higher (p < 0.05 when HA nanoparticles were incorporated within the HBMSC culture system. Histological evidence confirmed a distinct spatial transition zone, rich in calcium phosphate deposits. Assessment of explanted rabbit knees by histology demonstrated that cellularity within the repair tissues that had filled the defects were of significantly higher number (p < 0.05 when HA was used. HA nanoparticles play an important role in treating chondral defects when osteoarthritis is a co-morbidity. We speculate that the calcified layer formation at the interface in the osteoarthritic environment in the presence of HA is likely to have attributed to higher interfacial strength found in vitro. From an in vivo standpoint, the presence of HA promoted cellularity in the tissues that subsequently filled the chondral defects. This higher presence of cells can be considered important in the context of accelerating long-term cartilage remodeling. We conclude that HA nanoparticles play an important role in
Toolkit for local decision makers aims to strengthen environmental sustainability
CSIR Research Space (South Africa)
Murambadoro, M
2011-11-01
Full Text Available Members of the South African Risk and Vulnerability Atlas were involved in a meeting aimed at the development of a toolkit towards improved integration of climate change into local government's integrated development planning (IDP) process....
Guo, Liang; Lu, Mingmin; Li, Qianqian; Zhang, Jiawen; Zong, Yan; She, Zonglian
2014-11-01
The hydrolysis effect of waste sludge after multi-enzyme and thermophilic bacteria pretreatments is investigated using excitation-emission matrix (EEM) with fluorescence regional integration (FRI) in this study. The compositional characteristics of extracellular polymeric substances (EPS) and dissolved organic matters (DOM) were analyzed to evaluate the sludge disintegration. The EPS and cell wall in sludge were disrupted after hydrolysis which led to carbohydrate, protein and soluble chemical oxygen demand (SCOD) of DOM increasing in sludge supernatant. The bio-degradability level in the extracted fractions of EPS and DOM depending on the fluorescence zones was found after hydrolysis. The highest proportion of percent fluorescence response (Pi,n) in EPS and DOM was soluble microbial by-product and humic acid-like organics. A significant increase of humic acid-like organics in DOM after thermophilic bacteria hydrolysis was obtained. The assessment of hydrolysis using EEM coupled with FRI provided a new insight toward the bio-utilization process of waste sludge. Copyright © 2014 Elsevier Ltd. All rights reserved.
Bodewig, E
1959-01-01
Matrix Calculus, Second Revised and Enlarged Edition focuses on systematic calculation with the building blocks of a matrix and rows and columns, shunning the use of individual elements. The publication first offers information on vectors, matrices, further applications, measures of the magnitude of a matrix, and forms. The text then examines eigenvalues and exact solutions, including the characteristic equation, eigenrows, extremum properties of the eigenvalues, bounds for the eigenvalues, elementary divisors, and bounds for the determinant. The text ponders on approximate solutions, as well
Matrix theory selected topics and useful results
Mehta, Madan Lal
1989-01-01
Matrices and operations on matrices ; determinants ; elementary operations on matrices (continued) ; eigenvalues and eigenvectors, diagonalization of normal matrices ; functions of a matrix ; positive definiteness, various polar forms of a matrix ; special matrices ; matrices with quaternion elements ; inequalities ; generalised inverse of a matrix ; domain of values of a matrix, location and dispersion of eigenvalues ; symmetric functions ; integration over matrix variables ; permanents of doubly stochastic matrices ; infinite matrices ; Alexander matrices, knot polynomials, torsion numbers.
Directory of Open Access Journals (Sweden)
Kang-In Lee
2016-01-01
Full Text Available Human induced pluripotent stem cells (iPS cells hold great promise in the field of regenerative medicine, especially immune-compatible cell therapy. The most important safety-related issues that must be resolved before the clinical use of iPS cells include the generation of “footprint-free” and “xeno-free” iPS cells. In this study, we sought to examine whether an extracellular matrix- (ECM- based xeno-free culture system that we recently established could be used together with a microRNA-enhanced mRNA reprogramming method for the generation of clinically safe iPS cells. The notable features of this method are the use of a xeno-free/feeder-free culture system for the generation and expansion of iPS cells rather than the conventional labor-intensive culture systems using human feeder cells or human feeder-conditioned medium and the enhancement of mRNA-mediated reprogramming via the delivery of microRNAs. Strikingly, we observed the early appearance of iPS cell colonies (~11 days, substantial reprogramming efficiency (~0.2–0.3%, and a high percentage of ESC-like colonies among the total colonies (~87.5%, indicating enhanced kinetics and reprogramming efficiency. Therefore, the combined method established in this study provides a valuable platform for the generation and expansion of clinically safe (i.e., integration- and xeno-free iPS cells, facilitating immune-matched cell therapy in the near future.
de Soure, António M; Fernandes-Platzgummer, Ana; Moreira, Francisco; Lilaia, Carla; Liu, Shi-Hwei; Ku, Chen-Peng; Huang, Yi-Feng; Milligan, William; Cabral, Joaquim M S; da Silva, Cláudia L
2017-05-01
Umbilical cord matrix (UCM)-derived mesenchymal stem/stromal cells (MSCs) are promising therapeutic candidates for regenerative medicine settings. UCM MSCs have advantages over adult cells as these can be obtained through a non-invasive harvesting procedure and display a higher proliferative capacity. However, the high cell doses required in the clinical setting make large-scale manufacturing of UCM MSCs mandatory. A commercially available human platelet lysate-based culture supplement (UltraGRO TM , AventaCell BioMedical) (5%(v/v)) was tested to effectively isolate UCM MSCs and to expand these cells under (1) static conditions, using planar culture systems and (2) stirred culture using plastic microcarriers in a spinner flask. The MSC-like cells were isolated from UCM explant cultures after 11 ± 2 days. After five passages in static culture, UCM MSCs retained their immunophenotype and multilineage differentiation potential. The UCM MSCs cultured under static conditions using UltraGRO TM -supplemented medium expanded more rapidly compared with UCM MSCs expanded using a previously established protocol. Importantly, UCM MSCs were successfully expanded under dynamic conditions on plastic microcarriers using UltraGRO TM -supplemented medium in spinner flasks. Upon an initial 54% cell adhesion to the beads, UCM MSCs expanded by >13-fold after 5-6 days, maintaining their immunophenotype and multilineage differentiation ability. The present paper reports the establishment of an easily scalable integrated culture platform based on a human platelet lysate supplement for the effective isolation and expansion of UCM MSCs in a xenogeneic-free microcarrier-based system. This platform represents an important advance in obtaining safer and clinically meaningful MSC numbers for clinical translation. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.
Furthering the Aim of Multi- lingualism through Integrated ...
African Journals Online (AJOL)
R.B. Ruthven
The list is divided into nine chapters: psychology as a science and a profession, physio- logical psychology, sensation and perception, state of consciousness, learning, memory, intelligence, thinking and language, and motivation and emotion. The terms were initially drawn from the book Psychology: An Introduction for Stu- ...
Chen, Yingzhi; Huang, Zheng-Hong; Yue, Mengbin; Kang, Feiyu
2014-01-21
Organic nanostructures in terms of porphyrin building blocks have shown great potential in visible-light photocatalytic applications because of their optical, electrical, and catalytic properties. Graphenes are known to provide a high-quality two-dimensional (2D) support for inorganic semiconductor nanostructures to increase the adsorption capability of the photocatalysts and an electron-transfer medium with attractive potential to enhance photogenerated charge separation. A combination of porphyrin nanostructures with graphene sheets, particularly in the form of free-standing films, is highly desirable due to its photocatalysing feasibility and convenience. Toward this aim, we demonstrate a facile method to integrate porphyrin (meso-tetra(p-hydroxyphenyl)porphyrin, p-THPP) nanoparticles (NPs) into macroscopic graphene (reduced graphene oxide, rGO) films through vacuum filtration of the co-colloids of graphene oxide (GO) and p-THPP nanoparticles (NPs) followed by gaseous reduction. The obtained p-THPP/rGO nanohybrid film exhibits enhanced visible-light photocatalytic activity compared to each moiety of the hybrid, and this photocatalyst can be easily separated and recycled for successive use with excellent stability. The results show that this facile fabrication of the p-THPP/rGO nanohybrid film makes it available for high-performance optoelectronic applications, as well as for device integration.
DEFF Research Database (Denmark)
Emerek, Ruth
2004-01-01
Bidraget diskuterer de forskellige intergrationsopfattelse i Danmark - og hvad der kan forstås ved vellykket integration......Bidraget diskuterer de forskellige intergrationsopfattelse i Danmark - og hvad der kan forstås ved vellykket integration...
International Nuclear Information System (INIS)
Craps, Ben; Evnin, Oleg; Nguyen, Kévin
2017-01-01
Matrix quantum mechanics offers an attractive environment for discussing gravitational holography, in which both sides of the holographic duality are well-defined. Similarly to higher-dimensional implementations of holography, collapsing shell solutions in the gravitational bulk correspond in this setting to thermalization processes in the dual quantum mechanical theory. We construct an explicit, fully nonlinear supergravity solution describing a generic collapsing dilaton shell, specify the holographic renormalization prescriptions necessary for computing the relevant boundary observables, and apply them to evaluating thermalizing two-point correlation functions in the dual matrix theory.
Craps, Ben; Evnin, Oleg; Nguyen, Kévin
2017-02-01
Matrix quantum mechanics offers an attractive environment for discussing gravitational holography, in which both sides of the holographic duality are well-defined. Similarly to higher-dimensional implementations of holography, collapsing shell solutions in the gravitational bulk correspond in this setting to thermalization processes in the dual quantum mechanical theory. We construct an explicit, fully nonlinear supergravity solution describing a generic collapsing dilaton shell, specify the holographic renormalization prescriptions necessary for computing the relevant boundary observables, and apply them to evaluating thermalizing two-point correlation functions in the dual matrix theory.
Energy Technology Data Exchange (ETDEWEB)
Craps, Ben [Theoretische Natuurkunde, Vrije Universiteit Brussel (VUB), and International Solvay Institutes, Pleinlaan 2, B-1050 Brussels (Belgium); Evnin, Oleg [Department of Physics, Faculty of Science, Chulalongkorn University, Thanon Phayathai, Pathumwan, Bangkok 10330 (Thailand); Theoretische Natuurkunde, Vrije Universiteit Brussel (VUB), and International Solvay Institutes, Pleinlaan 2, B-1050 Brussels (Belgium); Nguyen, Kévin [Theoretische Natuurkunde, Vrije Universiteit Brussel (VUB), and International Solvay Institutes, Pleinlaan 2, B-1050 Brussels (Belgium)
2017-02-08
Matrix quantum mechanics offers an attractive environment for discussing gravitational holography, in which both sides of the holographic duality are well-defined. Similarly to higher-dimensional implementations of holography, collapsing shell solutions in the gravitational bulk correspond in this setting to thermalization processes in the dual quantum mechanical theory. We construct an explicit, fully nonlinear supergravity solution describing a generic collapsing dilaton shell, specify the holographic renormalization prescriptions necessary for computing the relevant boundary observables, and apply them to evaluating thermalizing two-point correlation functions in the dual matrix theory.
On matrix fractional differential equations
Adem Kılıçman; Wasan Ajeel Ahmood
2017-01-01
The aim of this article is to study the matrix fractional differential equations and to find the exact solution for system of matrix fractional differential equations in terms of Riemann–Liouville using Laplace transform method and convolution product to the Riemann–Liouville fractional of matrices. Also, we show the theorem of non-homogeneous matrix fractional partial differential equation with some illustrative examples to demonstrate the effectiveness of the new methodology. The main objec...
AIM cryocooler developments for HOT detectors
Rühlich, I.; Mai, M.; Withopf, A.; Rosenhagen, C.
2014-06-01
Significantly increased FPA temperatures for both Mid Wave and Long Wave IR detectors, i.e. HOT detectors, which have been developed in recent years are now leaving the development phase and are entering real application. HOT detectors allowing to push size weight and power (SWaP) of Integrated Detectors Cooler Assemblies (IDCA's) to a new level. Key component mainly driving achievable weight, volume and power consumption is the cryocooler. AIM cryocooler developments are focused on compact, lightweight linear cryocoolers driven by compact and high efficient digital cooler drive electronics (DCE) to also achieve highest MTTF targets. This technology is using moving magnet driving mechanisms and dual or single piston compressors. Whereas SX030 which was presented at SPIE in 2012 consuming less 3 WDC to operate a typical IDCA at 140K, next smaller cooler SX020 is designed to provide sufficient cooling power at detector temperature above 160K. The cooler weight of less than 200g and a total compressor length of 60mm makes it an ideal solution for all applications with limited weight and power budget, like in handheld applications. For operating a typical 640x512, 15μm MW IR detector the power consumption will be less than 1.5WDC. MTTF for the cooler will be in excess of 30,000h and thus achieving low maintenance cost also in 24/7 applications. The SX020 compressor is based on a single piston design with integrated passive balancer in a new design achieves very low exported vibration in the order of 100mN in the compressor axis. AIM is using a modular approach, allowing the chose between 5 different compressor types for one common Stirling expander. The 6mm expander with a total length of 74mm is now available in a new design that fits into standard dewar bores originally designed for rotary coolers. Also available is a 9mm coldfinger in both versions. In development is an ultra-short expander with around 35mm total length to achieve highest compactness. Technical
Ding, Jun; Xiao, Hua-Ming; Liu, Simin; Wang, Chang; Liu, Xin; Feng, Yu-Qi
2018-10-05
Although several methods have realized the analysis of low molecular weight (LMW) compounds using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) by overcoming the problem of interference with MS signals in the low mass region derived from conventional organic matrices, this emerging field still requires strategies to address the issue of analyzing complex samples containing LMW components in addition to the LMW compounds of interest, and solve the problem of lack of universality. The present study proposes an integrated strategy that combines chemical labeling with the supramolecular chemistry of cucurbit [n]uril (CB [n]) for the MALDI MS analysis of LMW compounds in complex samples. In this strategy, the target LMW compounds are first labeled by introducing a series of bifunctional reagents that selectively react with the target analytes and also form stable inclusion complexes with CB [n]. Then, the labeled products act as guest molecules that readily and selectively form stable inclusion complexes with CB [n]. This strategy relocates the MS signals of the LMW compounds of interest from the low mass region suffering high interference to the high mass region where interference with low mass components is absent. Experimental results demonstrate that a wide range of LMW compounds, including carboxylic acids, aldehydes, amines, thiol, and cis-diols, can be successfully detected using the proposed strategy, and the limits of detection were in the range of 0.01-1.76 nmol/mL. In addition, the high selectivity of the labeling reagents for the target analytes in conjunction with the high selectivity of the binding between the labeled products and CB [n] ensures an absence of signal interference with the non-targeted LMW components of complex samples. Finally, the feasibility of the proposed strategy for complex sample analysis is demonstrated by the accurate and rapid quantitative analysis of aldehydes in saliva and herbal
Gómez Rodríguez, Rafael Ángel
2014-01-01
To say that someone possesses integrity is to claim that that person is almost predictable about responses to specific situations, that he or she can prudentially judge and to act correctly. There is a closed interrelationship between integrity and autonomy, and the autonomy rests on the deeper moral claim of all humans to integrity of the person. Integrity has two senses of significance for medical ethic: one sense refers to the integrity of the person in the bodily, psychosocial and intellectual elements; and in the second sense, the integrity is the virtue. Another facet of integrity of the person is la integrity of values we cherish and espouse. The physician must be a person of integrity if the integrity of the patient is to be safeguarded. The autonomy has reduced the violations in the past, but the character and virtues of the physician are the ultimate safeguard of autonomy of patient. A field very important in medicine is the scientific research. It is the character of the investigator that determines the moral quality of research. The problem arises when legitimate self-interests are replaced by selfish, particularly when human subjects are involved. The final safeguard of moral quality of research is the character and conscience of the investigator. Teaching must be relevant in the scientific field, but the most effective way to teach virtue ethics is through the example of the a respected scientist.
Brenner, Barbara; Schlegelmilch, Bodo B.; Ambos, Björn
2013-01-01
This case describes how Nike, a consumer goods company with an ever expanding portfolio and a tremendous brand value, manages the tradeoff between local responsiveness and global integration. In particular, the case highlights Nike's organizational structure that consists of a global matrix organization that is replicated at a regional level for the European market. While this organizational structure allows Nike to respond to local consumer tastes it also ensures that the company benefits f...
Confocal microscopy imaging of the biofilm matrix
DEFF Research Database (Denmark)
Schlafer, Sebastian; Meyer, Rikke L
2017-01-01
The extracellular matrix is an integral part of microbial biofilms and an important field of research. Confocal laser scanning microscopy is a valuable tool for the study of biofilms, and in particular of the biofilm matrix, as it allows real-time visualization of fully hydrated, living specimens...... the concentration of solutes and the diffusive properties of the biofilm matrix....
Garoufalidis, S; Garoufalidis, Stavros; Marino, Marcos
2006-01-01
The contribution of reducible connections to the U(N) Chern-Simons invariant of a Seifert manifold $M$ can be expressed in some cases in terms of matrix integrals. We show that the U(N) evaluation of the LMO invariant of any rational homology sphere admits a matrix model representation which agrees with the Chern-Simons matrix integral for Seifert spheres and the trivial connection.
Machining of Metal Matrix Composites
2012-01-01
Machining of Metal Matrix Composites provides the fundamentals and recent advances in the study of machining of metal matrix composites (MMCs). Each chapter is written by an international expert in this important field of research. Machining of Metal Matrix Composites gives the reader information on machining of MMCs with a special emphasis on aluminium matrix composites. Chapter 1 provides the mechanics and modelling of chip formation for traditional machining processes. Chapter 2 is dedicated to surface integrity when machining MMCs. Chapter 3 describes the machinability aspects of MMCs. Chapter 4 contains information on traditional machining processes and Chapter 5 is dedicated to the grinding of MMCs. Chapter 6 describes the dry cutting of MMCs with SiC particulate reinforcement. Finally, Chapter 7 is dedicated to computational methods and optimization in the machining of MMCs. Machining of Metal Matrix Composites can serve as a useful reference for academics, manufacturing and materials researchers, manu...
Bhatia, Rajendra
1997-01-01
A good part of matrix theory is functional analytic in spirit. This statement can be turned around. There are many problems in operator theory, where most of the complexities and subtleties are present in the finite-dimensional case. My purpose in writing this book is to present a systematic treatment of methods that are useful in the study of such problems. This book is intended for use as a text for upper division and gradu ate courses. Courses based on parts of the material have been given by me at the Indian Statistical Institute and at the University of Toronto (in collaboration with Chandler Davis). The book should also be useful as a reference for research workers in linear algebra, operator theory, mathe matical physics and numerical analysis. A possible subtitle of this book could be Matrix Inequalities. A reader who works through the book should expect to become proficient in the art of deriving such inequalities. Other authors have compared this art to that of cutting diamonds. One first has to...
Cotrufo, M Francesca; Wallenstein, Matthew D; Boot, Claudia M; Denef, Karolien; Paul, Eldor
2013-04-01
The decomposition and transformation of above- and below-ground plant detritus (litter) is the main process by which soil organic matter (SOM) is formed. Yet, research on litter decay and SOM formation has been largely uncoupled, failing to provide an effective nexus between these two fundamental processes for carbon (C) and nitrogen (N) cycling and storage. We present the current understanding of the importance of microbial substrate use efficiency and C and N allocation in controlling the proportion of plant-derived C and N that is incorporated into SOM, and of soil matrix interactions in controlling SOM stabilization. We synthesize this understanding into the Microbial Efficiency-Matrix Stabilization (MEMS) framework. This framework leads to the hypothesis that labile plant constituents are the dominant source of microbial products, relative to input rates, because they are utilized more efficiently by microbes. These microbial products of decomposition would thus become the main precursors of stable SOM by promoting aggregation and through strong chemical bonding to the mineral soil matrix. © 2012 Blackwell Publishing Ltd.
Applying transpose matrix on advanced encryption standard (AES) for database content
Manurung, E. B. P.; Sitompul, O. S.; Suherman
2018-03-01
Advanced Encryption Standard (AES) is a specification for the encryption of electronic data established by the U.S. National Institute of Standards and Technology (NIST) and has been adopted by the U.S. government and is now used worldwide. This paper reports the impact of transpose matrix integration to AES. Transpose matrix implementation on AES is aimed at first stage of chypertext modifications for text based database security so that the confidentiality improves. The matrix is also able to increase the avalanche effect of the cryptography algorithm 4% in average.
Belitsky, A. V.
2017-10-01
The Operator Product Expansion for null polygonal Wilson loop in planar maximally supersymmetric Yang-Mills theory runs systematically in terms of multi-particle pentagon transitions which encode the physics of excitations propagating on the color flux tube ending on the sides of the four-dimensional contour. Their dynamics was unraveled in the past several years and culminated in a complete description of pentagons as an exact function of the 't Hooft coupling. In this paper we provide a solution for the last building block in this program, the SU(4) matrix structure arising from internal symmetry indices of scalars and fermions. This is achieved by a recursive solution of the Mirror and Watson equations obeyed by the so-called singlet pentagons and fixing the form of the twisted component in their tensor decomposition. The non-singlet, or charged, pentagons are deduced from these by a limiting procedure.
Directory of Open Access Journals (Sweden)
A.V. Belitsky
2017-10-01
Full Text Available The Operator Product Expansion for null polygonal Wilson loop in planar maximally supersymmetric Yang–Mills theory runs systematically in terms of multi-particle pentagon transitions which encode the physics of excitations propagating on the color flux tube ending on the sides of the four-dimensional contour. Their dynamics was unraveled in the past several years and culminated in a complete description of pentagons as an exact function of the 't Hooft coupling. In this paper we provide a solution for the last building block in this program, the SU(4 matrix structure arising from internal symmetry indices of scalars and fermions. This is achieved by a recursive solution of the Mirror and Watson equations obeyed by the so-called singlet pentagons and fixing the form of the twisted component in their tensor decomposition. The non-singlet, or charged, pentagons are deduced from these by a limiting procedure.
Chen, C.; Chen, Z.; Bera, Deep; Raghunathan, S.B.; ShabaniMotlagh, M.; Noothout, E.C.; Chang, Z.Y.; Ponte, Jacco; Prins, Christian; Vos, H.J.; Bosch, Johan G.; Verweij, M.D.; de Jong, N.; Pertijs, M.A.P.
2017-01-01
This paper presents a power-and area-efficient front-end application-specific integrated circuit (ASIC) that is directly integrated with an array of 32 × 32 piezoelectric transducer elements to enable next-generation miniature ultrasound probes for real-time 3-D transesophageal echocardiography.
Supersymmetry in random matrix theory
International Nuclear Information System (INIS)
Kieburg, Mario
2010-01-01
I study the applications of supersymmetry in random matrix theory. I generalize the supersymmetry method and develop three new approaches to calculate eigenvalue correlation functions. These correlation functions are averages over ratios of characteristic polynomials. In the first part of this thesis, I derive a relation between integrals over anti-commuting variables (Grassmann variables) and differential operators with respect to commuting variables. With this relation I rederive Cauchy- like integral theorems. As a new application I trace the supermatrix Bessel function back to a product of two ordinary matrix Bessel functions. In the second part, I apply the generalized Hubbard-Stratonovich transformation to arbitrary rotation invariant ensembles of real symmetric and Hermitian self-dual matrices. This extends the approach for unitarily rotation invariant matrix ensembles. For the k-point correlation functions I derive supersymmetric integral expressions in a unifying way. I prove the equivalence between the generalized Hubbard-Stratonovich transformation and the superbosonization formula. Moreover, I develop an alternative mapping from ordinary space to superspace. After comparing the results of this approach with the other two supersymmetry methods, I obtain explicit functional expressions for the probability densities in superspace. If the probability density of the matrix ensemble factorizes, then the generating functions exhibit determinantal and Pfaffian structures. For some matrix ensembles this was already shown with help of other approaches. I show that these structures appear by a purely algebraic manipulation. In this new approach I use structures naturally appearing in superspace. I derive determinantal and Pfaffian structures for three types of integrals without actually mapping onto superspace. These three types of integrals are quite general and, thus, they are applicable to a broad class of matrix ensembles. (orig.)
Supersymmetry in random matrix theory
Energy Technology Data Exchange (ETDEWEB)
Kieburg, Mario
2010-05-04
I study the applications of supersymmetry in random matrix theory. I generalize the supersymmetry method and develop three new approaches to calculate eigenvalue correlation functions. These correlation functions are averages over ratios of characteristic polynomials. In the first part of this thesis, I derive a relation between integrals over anti-commuting variables (Grassmann variables) and differential operators with respect to commuting variables. With this relation I rederive Cauchy- like integral theorems. As a new application I trace the supermatrix Bessel function back to a product of two ordinary matrix Bessel functions. In the second part, I apply the generalized Hubbard-Stratonovich transformation to arbitrary rotation invariant ensembles of real symmetric and Hermitian self-dual matrices. This extends the approach for unitarily rotation invariant matrix ensembles. For the k-point correlation functions I derive supersymmetric integral expressions in a unifying way. I prove the equivalence between the generalized Hubbard-Stratonovich transformation and the superbosonization formula. Moreover, I develop an alternative mapping from ordinary space to superspace. After comparing the results of this approach with the other two supersymmetry methods, I obtain explicit functional expressions for the probability densities in superspace. If the probability density of the matrix ensemble factorizes, then the generating functions exhibit determinantal and Pfaffian structures. For some matrix ensembles this was already shown with help of other approaches. I show that these structures appear by a purely algebraic manipulation. In this new approach I use structures naturally appearing in superspace. I derive determinantal and Pfaffian structures for three types of integrals without actually mapping onto superspace. These three types of integrals are quite general and, thus, they are applicable to a broad class of matrix ensembles. (orig.)
DEFF Research Database (Denmark)
Olwig, Karen Fog
2011-01-01
, while the countries have adopted disparate policies and ideologies, differences in the actual treatment and attitudes towards immigrants and refugees in everyday life are less clear, due to parallel integration programmes based on strong similarities in the welfare systems and in cultural notions...... of equality in the three societies. Finally, it shows that family relations play a central role in immigrants’ and refugees’ establishment of a new life in the receiving societies, even though the welfare society takes on many of the social and economic functions of the family....
Take AIM and Keep Your Students Engaged
Nash, Catherine
2014-01-01
This paper outlines the benefits to distance education teachers of formatting a weekly online newsletter in accordance with motivational learning theory. It reflects on the delivery of weekly AIM newsletters to undergraduate economics students at the Open Polytechnic of New Zealand via Moodle. The acronym, AIM, stands for Academic content,…
Discrimination and the aim of proportional representation
DEFF Research Database (Denmark)
Lippert-Rasmussen, Kasper
2008-01-01
Many organizations, companies, and so on are committed to certain representational aims as regards the composition of their workforce. One motivation for such aims is the assumption that numerical underrepresentation of groups manifests discrimination against them. In this article, I articulate r...
Discrimination and the aim of proportional representation
DEFF Research Database (Denmark)
Lippert-Rasmussen, Kasper
2008-01-01
Many organizations, companies, and so on are committed to certain representational aims as regards the composition of their workforce. One motivation for such aims is the assumption that numerical underrepresentation of groups manifests discrimination against them. In this article, I articulate...... representational aims in a way that best captures this rationale. My main claim is that the achievement of such representational aims is reducible to the elimination of the effects of wrongful discrimination on individuals and that this very important concern is, in principle, compatible with the representation...... of discrimination against numerically overrepresented groups, or overlook the innocently different ambitions of some numerically underrepresented groups. In relation to the latter point, I appeal to the fact that many luck egalitarians think justice should be ambition sensitive (but endowment insensitive). Also...
Centola Michael B; Dozmorov Igor; Buethe David D; Saban Ricardo; Hauser Paul J; Kyker Kimberly D; Dozmorov Mikhail G; Culkin Daniel J; Hurst Robert E
2008-01-01
Abstract A statistically robust and biologically-based approach for analysis of microarray data is described that integrates independent biological knowledge and data with a global F-test for finding genes of interest that minimizes the need for replicates when used for hypothesis generation. First, each microarray is normalized to its noise level around zero. The microarray dataset is then globally adjusted by robust linear regression. Second, genes of interest that capture significant respo...
On matrix fractional differential equations
Directory of Open Access Journals (Sweden)
Adem Kılıçman
2017-01-01
Full Text Available The aim of this article is to study the matrix fractional differential equations and to find the exact solution for system of matrix fractional differential equations in terms of Riemann–Liouville using Laplace transform method and convolution product to the Riemann–Liouville fractional of matrices. Also, we show the theorem of non-homogeneous matrix fractional partial differential equation with some illustrative examples to demonstrate the effectiveness of the new methodology. The main objective of this article is to discuss the Laplace transform method based on operational matrices of fractional derivatives for solving several kinds of linear fractional differential equations. Moreover, we present the operational matrices of fractional derivatives with Laplace transform in many applications of various engineering systems as control system. We present the analytical technique for solving fractional-order, multi-term fractional differential equation. In other words, we propose an efficient algorithm for solving fractional matrix equation.
Is Fitts' law continuous in discrete aiming?
Directory of Open Access Journals (Sweden)
Rita Sleimen-Malkoun
Full Text Available The lawful continuous linear relation between movement time and task difficulty (i.e., index of difficulty; ID in a goal-directed rapid aiming task (Fitts' law has been recently challenged in reciprocal performance. Specifically, a discontinuity was observed at critical ID and was attributed to a transition between two distinct dynamic regimes that occurs with increasing difficulty. In the present paper, we show that such a discontinuity is also present in discrete aiming when ID is manipulated via target width (experiment 1 but not via target distance (experiment 2. Fitts' law's discontinuity appears, therefore, to be a suitable indicator of the underlying functional adaptations of the neuro-muscular-skeletal system to task properties/requirements, independently of reciprocal or discrete nature of the task. These findings open new perspectives to the study of dynamic regimes involved in discrete aiming and sensori-motor mechanisms underlying the speed-accuracy trade-off.
Energy Technology Data Exchange (ETDEWEB)
Alvares, Joao Malta [IX Consultoria e Representacoes Ltda, Itajuba, MG (Brazil); Universidade Federal de Itajuba (UNIFEI), MG (Brazil)
2010-07-01
A georeferenced information system energy or simply SIEG, is designed to integrate into the energy matrix of Sao Paulo from 2005 to 2035. Being an innovative request made by the Department of Sanitation and Energy of the state, this system would have the purpose to collect and aggregate information and data from several themes, relating this content in a geographic location spatialized. The main focus of the system is the analysis of the energy sector as a whole, from generation to final consumption, through all phases such as transmission and distribution. The energy data would also be crossed with various themes of support, contributing to the development of numerous reviews and generating sound conclusions. Issues such as environment, socio-economics, infrastructure, interconnected sectors, geographical conditions and other information could be entered, viewed and linked to the system. The SIEG is also a facilitator for planning and managing the energy sector with forecast models in possible future situations. (author)
International Nuclear Information System (INIS)
Efimov, V.N.; Schulz, H.
1976-01-01
It is shown that in the framework of the boundary condition models (BCM) for the two-particle interaction the Schroedinger equation for the system of three identical bosons can be reduced to the one-dimensional integral equation in an exact way. The method used for obtaining such an equation is based on a special consideration of the two-particle off-shell wave functions. The binding energy of the simple three-particle system is calculated. It is indicated that by means of the equation obtained it is possible to change the off-shell behaviour of the two-particle t-matrix and therefore to simulate three particle effects. (Auth.)
Flendrig, L. M.; la Soe, J. W.; Jörning, G. G.; Steenbeek, A.; Karlsen, O. T.; Bovée, W. M.; Ladiges, N. C.; te Velde, A. A.; Chamuleau, R. A.
1997-01-01
BACKGROUND/AIMS: The development of custom-made bioreactors for use as a bioartificial liver (BAL) is considered to be one of the last challenges on the road to successful temporary extracorporeal liver support therapy. We devised a novel bioreactor (patent pending) which allows individual perfusion
To Conclude: India can aim big
Indian Academy of Sciences (India)
... Transmission and Distribution Losses. If 100 million middle class homes deploy 1 kW on rooftops. 100 GW peak power capacity added at homes alone; 40% of current peak power installed in India today. India must aim by 2030. To have 50% of its electric power from SOLAR; To have 50% of vehicles as Electric Vehicles ...
Aims and harvest of moral case deliberation.
Weidema, Froukje C; Molewijk, Bert A C; Kamsteeg, Frans; Widdershoven, Guy A M
2013-09-01
Deliberative ways of dealing with ethical issues in health care are expanding. Moral case deliberation is an example, providing group-wise, structured reflection on dilemmas from practice. Although moral case deliberation is well described in literature, aims and results of moral case deliberation sessions are unknown. This research shows (a) why managers introduce moral case deliberation and (b) what moral case deliberation participants experience as moral case deliberation results. A responsive evaluation was conducted, explicating moral case deliberation experiences by analysing aims (N = 78) and harvest (N = 255). A naturalistic data collection included interviews with managers and evaluation questionnaires of moral case deliberation participants (nurses). From the analysis, moral case deliberation appeals for cooperation, team bonding, critical attitude towards routines and nurses' empowerment. Differences are that managers aim to foster identity of the nursing profession, whereas nurses emphasize learning processes and understanding perspectives. We conclude that moral case deliberation influences team cooperation that cannot be controlled with traditional management tools, but requires time and dialogue. Exchanging aims and harvest between manager and team could result in co-creating (moral) practice in which improvements for daily cooperation result from bringing together perspectives of managers and team members.
Pragmatics and the aims of language evolution.
Scott-Phillips, Thomas C
2017-02-01
Pragmatics has historically played a relatively peripheral role in language evolution research. This is a profound mistake. Here I describe how a pragmatic perspective can inform language evolution in the most fundamental way: by making clear what the natural objects of study are, and hence what the aims of the field should be.
Tutorial: Asteroseismic Stellar Modelling with AIMS
Lund, Mikkel N.; Reese, Daniel R.
The goal of aims (Asteroseismic Inference on a Massive Scale) is to estimate stellar parameters and credible intervals/error bars in a Bayesian manner from a set of asteroseismic frequency data and so-called classical constraints. To achieve reliable parameter estimates and computational efficiency, it searches through a grid of pre-computed models using an MCMC algorithm—interpolation within the grid of models is performed by first tessellating the grid using a Delaunay triangulation and then doing a linear barycentric interpolation on matching simplexes. Inputs for the modelling consist of individual frequencies from peak-bagging, which can be complemented with classical spectroscopic constraints. aims is mostly written in Python with a modular structure to facilitate contributions from the community. Only a few computationally intensive parts have been rewritten in Fortran in order to speed up calculations.
CURRICULUM MATTERS: Aims assessments and workplace needs
Black, Paul
1997-09-01
This paper attempts to consider the aims that undergraduate physics degree courses actually reflect and serve in the light of the employment patterns of graduates and of the expressed needs of employers. It reviews the results of analyses of what degree examinations actually test, and goes on to quote criticisms of their courses and radical proposals to change them adopted by the UK conference of physics professors. The discussion is then broadened by discussion of evidence, about the employment of graduates and about the priorities that some industrialists now give in the qualities that they look for when recruiting new graduates. The evidence leads to a view that radical changes are needed, both in courses and examinations, and that there is a need for university departments to work more closely with employers in re-formulating the aims and priorities in their teaching.
Aims and methods of nuclear materials management
International Nuclear Information System (INIS)
Leven, D.; Schier, H.
1979-05-01
Whilst international safeguarding of fissile materials against abuse has been the subject of extensive debate, little public attention has so far been devoted to the internal security of these materials. All countries using nuclear energy for peaceful purposes have laid down appropriate regulations. In the Federal Republic of Germany safeguards are required, for instance, by the Atomic Energy Act, and are therefore a prerequisite for licensing. The aims and methods of national nuclear materials management are contrasted with viewpoints on international safeguards
Directory of Open Access Journals (Sweden)
Maria Salete Bessa Jorge
2012-01-01
Full Text Available OBJECTIVE: To analyze how the matrix support in mental health contributes to the production of comprehensive care with an emphasis on the interrelationships between worker / user / family. METHODS: Research with a qualitative approach that used the techniques of interview, focus group and systematic observation. Data analysis was based on critical hermeneutics. RESULTS: Matrix support in mental health assumes pedagogical and technical assistance dimensions, which favor the interaction between primary care teams and specialist teams of the Center for Psychosocial Care (CAPS, ensuring territorially-based care, with interaction of different knowledge and practices. It further contributes to the redirection of the flow of users in seeking care for their health needs, articulating the levels of health care. The worker / user / family interrelationships are closer and allow better accommodation to the demands and bond of the team with the user and his family. However, difficulties such as consolidation of the matrix support, and the predominance of biomedical practice are noted. CONCLUSION: The matrix support contributes an expansion of the spaces of mental health care in the territory, opening living spaces, creation in the reaction of the worker / user / family, and thus configuring itself as a device for the production of integrated care.OBJETIVO: Analizar cómo el apoyo matricial en salud mental contribuye con la producción del cuidado integral con énfasis en las interrelaciones entre trabajador/usuario/familia. MÉTODOS: Investigación con abordaje cualitativo en el que se utilizó las técnicas de entrevista, grupo focal y observación sistemática. El análisis de los datos se fundamentó en la hermenéutica crítica. RESULTADOS: El apoyo matricial en salud mental asume dimensiones pedagógicas y técnico-asistenciales, que favorecen la interacción entre equipos de la atención básica y equipos especializados del Centro de Atenci
Rifkin takes aim at USDA animal research.
Fox, Jeffrey L
1984-10-19
Jeremy Rifkin has filed a lawsuit to block U.S. Department of Agriculture (USDA) experiments involving the transfer of human growth hormone genes into sheep and pigs, which he rejects on environmental, economic, and ethical grounds. His real target is the Department's animal breeding program; his ultimate aim is "to establish the principle that there should be no crossing of species barriers in animals." USDA officials have not yet responded to the lawsuit but they intend to continue the experiments, which they consider crucial to the progress of research, until told to stop.
The aims of transfer prices formation
Directory of Open Access Journals (Sweden)
Tomašević Stevan
2013-01-01
Full Text Available More than two-thirds of today's world trade comprises of transactions between related legal persons. Prices for the above-mentioned transactions within legal person or group of related legal persons are called transfer pricing. The aim of this paper is to present the transfer prices as well as the main objectives of transfer pricing. Also, this paper explains application of transfer pricing in the Republic of Serbia and the normative rules that cover the issue of transfer pricing, their determination and their application in the calculation. Overall, there has been a great deal of attention paid to the transfer pricing in national and international levels.
Aims and methods of education: A recapitulation
Directory of Open Access Journals (Sweden)
Pantić Nataša
2007-01-01
Full Text Available This paper gives an overview of principal distinction between the aims of the so-called "traditional" and "progressive" education and respective pedagogies associated with each. The term "traditional" education is used to denote the kind of education that prepares people for their role in society as it is, while the term "progressive" is used for education that aspires to equip mankind with capacity to shape the change of society. The paper raises some critical questions about the role of pedagogy in achieving the aims of the progressive model, arguing that the employment of "progressive" methods does not necessarily guarantee the achievement of the commonly professed purposes of progressive education. This is illustrated in the paper by the results of a study in English schools showing how despite the claim of progressive methods, teachers tend to retain traditional attitudes and on the other hand, how even traditional teaching methods can serve the progressive purpose. This is not to advocate for the traditional pedagogy, but to suggest that it might be something other than pedagogy that makes a critical difference in educating liberal-minded citizens of the future. In this sense the paper explores the role of other factors that make a difference towards progressive education, such as democratization of human relations in school ethos and respect for children's freedom.
Directory of Open Access Journals (Sweden)
T. N. Zhilnikova
2016-01-01
Full Text Available Objectives. The formation of the structure of hardened concrete grouting with two-stage expansion is a complex process that is influenced by many factors, both of a prescriptive nature (composition and additive dosage, mineralogical composition of Portland cement clinker, concrete composition, the presence of chemical additives and in terms of process (the fineness of cement grinding, temperature of curing, etc.. Methods. In order to assess the impact of the above factors, the article proposes the introduction of a number of integrated indicators being characterised as a process in which influences are shown alongside the factor generating the influence. For the evaluation of the influence of different factors on the process of gas generation, an effectiveness ratio of gas generation is proposed by the authors. Results. The article presents the results of an investigation into the influence of the amount of gassing agent and the type and dosage of superplasticiser on the process of gassing by means of the displacement method on the mortar mix. The authors similarly propose a expansion efficiency coefficient. The article presents the results of the investigation into the influence of the amount of gassing agent, the presence and amount of superplasticiser, the sand/cement ratio, aggregate size and water-cement ratio during the first stage of expansion of the mixture. The authors propose a formula for describing the dependence of the relative expansion deformations on the concentration of filler. In order to assess the conditions in which a mixture is present, it is proposed to use an indicator consisting in the constraint expansion coefficient. Conclusion. Use of the hardening condition coefficient is proposed as a means of accounting for the effect of curing conditions on the strength of the concrete grouting with two-stage expansion. The authors recommend taking the introduction of correction factors into account when considering the impact of
Plasma health care - Aims, constraints and progress
International Nuclear Information System (INIS)
Morfill, G.E.; Zimmerman, J.L.
2013-01-01
Health Care covers three areas of interest for cold atmospheric pressure plasmas: Cosmetics, Hygiene and Medicine. These areas can be subdivided into personal and professional care. In this review will concentrate on Hygiene and Medicine. In professional hygiene the most important plasma contribution is sterilization, decontamination and disinfection. The main aim is the prevention of diseases or their containment. Progress in the development of efficient bactericidal plasma sources has been rapid, so that it appears realistic to use plasmas to combat nosocomial infections as well as community associated infections in the not too distant future. The advantages of plasma devices – they use air and electricity only, there are no waste products, they are inexpensive to manufacture and operate, easy to transport and install, and bactericidal effects are fast (seconds). Plasmas can efficiently kill resistant bacteria (e.g. MRSA) and tests have shown no resistance build-up so far. With an estimated 2 Million hospital induced infections each year in the US alone, and about 100.000 resulting deaths, very efficient, safe and fast hospital plasma hygiene devices would appear to be a very important weapon to help contain the spread of infectious diseases. In Medicine there are a number of ambitious ideas and aims. Plasmas can be “designed” to some extent. They can include different active species that can have an effect at the cellular level. There are ionic atoms and molecules, whose medical use need to be evaluated – the vision is that a new area of “plasma pharmacy” could develop. First steps are currently being taken in biological studies. Also the excited atoms in cold atmospheric plasmas may make cell walls more permeable for such species. (author)
The cellulose resource matrix.
Keijsers, Edwin R P; Yılmaz, Gülden; van Dam, Jan E G
2013-03-01
feedstock and the performance in the end-application. The cellulose resource matrix should become a practical tool for stakeholders to make choices regarding raw materials, process or market. Although there is a vast amount of scientific and economic information available on cellulose and lignocellulosic resources, the accessibility for the interested layman or entrepreneur is very difficult and the relevance of the numerous details in the larger context is limited. Translation of science to practical accessible information with modern data management and data integration tools is a challenge. Therefore, a detailed matrix structure was composed in which the different elements or entries of the matrix were identified and a tentative rough set up was made. The inventory includes current commodities and new cellulose containing and raw materials as well as exotic sources and specialties. Important chemical and physical properties of the different raw materials were identified for the use in processes and products. When available, the market data such as price and availability were recorded. Established and innovative cellulose extraction and refining processes were reviewed. The demands on the raw material for suitable processing were collected. Processing parameters known to affect the cellulose properties were listed. Current and expected emerging markets were surveyed as well as their different demands on cellulose raw materials and processes. The setting up of the cellulose matrix as a practical tool requires two steps. Firstly, the reduction of the needed data by clustering of the characteristics of raw materials, processes and markets and secondly, the building of a database that can provide the answers to the questions from stakeholders with an indicative character. This paper describes the steps taken to achieve the defined clusters of most relevant and characteristic properties. These data can be expanded where required. More detailed specification can be obtained
Efficiency criterion for teleportation via channel matrix, measurement matrix and collapsed matrix
Directory of Open Access Journals (Sweden)
Xin-Wei Zha
Full Text Available In this paper, three kinds of coefficient matrixes (channel matrix, measurement matrix, collapsed matrix associated with the pure state for teleportation are presented, the general relation among channel matrix, measurement matrix and collapsed matrix is obtained. In addition, a criterion for judging whether a state can be teleported successfully is given, depending on the relation between the number of parameter of an unknown state and the rank of the collapsed matrix. Keywords: Channel matrix, Measurement matrix, Collapsed matrix, Teleportation
Rozov, V.; Alekseev, A.
2015-08-01
A necessity to address a wide spectrum of engineering problems in ITER determined the need for efficient tools for modeling of the magnetic environment and force interactions between the main components of the magnet system. The assessment of the operating window for the machine, determined by the electro-magnetic (EM) forces, and the check of feasibility of particular scenarios play an important role for ensuring the safety of exploitation. Such analysis-powered prevention of damages forms an element of the Machine Operations and Investment Protection strategy. The corresponding analysis is a necessary step in preparation of the commissioning, which finalizes the construction phase. It shall be supported by the development of the efficient and robust simulators and multi-physics/multi-system integration of models. The developed numerical model of interactions in the ITER magnetic system, based on the use of pre-computed influence matrices, facilitated immediate and complete assessment and systematic specification of EM loads on magnets in all foreseen operating regimes, their maximum values, envelopes and the most critical scenarios. The common principles of interaction in typical bilateral configurations have been generalized for asymmetry conditions, inspired by the plasma and by the hardware, including asymmetric plasma event and magnetic system fault cases. The specification of loads is supported by the technology of functional approximation of nodal and distributed data by continuous patterns/analytical interpolants. The global model of interactions together with the mesh-independent analytical format of output provides the source of self-consistent and transferable data on the spatial distribution of the system of forces for assessments of structural performance of the components, assemblies and supporting structures. The numerical model used is fully parametrized, which makes it very suitable for multi-variant and sensitivity studies (positioning, off
Matrix completion by deep matrix factorization.
Fan, Jicong; Cheng, Jieyu
2018-02-01
Conventional methods of matrix completion are linear methods that are not effective in handling data of nonlinear structures. Recently a few researchers attempted to incorporate nonlinear techniques into matrix completion but there still exists considerable limitations. In this paper, a novel method called deep matrix factorization (DMF) is proposed for nonlinear matrix completion. Different from conventional matrix completion methods that are based on linear latent variable models, DMF is on the basis of a nonlinear latent variable model. DMF is formulated as a deep-structure neural network, in which the inputs are the low-dimensional unknown latent variables and the outputs are the partially observed variables. In DMF, the inputs and the parameters of the multilayer neural network are simultaneously optimized to minimize the reconstruction errors for the observed entries. Then the missing entries can be readily recovered by propagating the latent variables to the output layer. DMF is compared with state-of-the-art methods of linear and nonlinear matrix completion in the tasks of toy matrix completion, image inpainting and collaborative filtering. The experimental results verify that DMF is able to provide higher matrix completion accuracy than existing methods do and DMF is applicable to large matrices. Copyright © 2017 Elsevier Ltd. All rights reserved.
On correlations in IMRT planning aims
Roy, Arkajyoti; Das, Indra J.
2016-01-01
The purpose was to study correlations amongst IMRT DVH evaluation points and how their relaxation impacts the overall plan. 100 head‐and‐neck cancer cases, using the Eclipse treatment planning system with the same protocol, are statistically analyzed for PTV, brainstem, and spinal cord. To measure variations amongst the plans, we use (i) interquartile range (IQR) of volume as a function of dose, (ii) interquartile range of dose as a function of volume, and (iii) dose falloff. To determine correlations for institutional and ICRU goals, conditional probabilities and medians are computed. We observe that most plans exceed the median PTV dose (average D50 = 104% prescribed dose). Furthermore, satisfying D50 reduced the probability of also satisfying D98, constituting a negative correlation of these goals. On the other hand, satisfying D50 increased the probability of satisfying D2, suggesting a positive correlation. A positive correlation is also observed between the PTV V105 and V110. Similarly, a positive correlation between the brainstem V45 and V50 is measured by an increase in the conditional median of V45, when V50 is violated. Despite the imposed institutional and international recommendations, significant variations amongst DVH points can occur. Even though DVH aims are evaluated independently, sizable correlations amongst them are possible, indicating that some goals cannot be satisfied concurrently, calling for unbiased plan criteria. PACS number(s): 87.55.dk, 87.53.Bn, 87.55.Qr, 87.55.de. PMID:27929480
Lorentzian 3d gravity with wormholes via matrix models
Ambjørn, J.; Jurkiewicz, J.; Loll, R.; Vernizzi, G.
2001-01-01
We uncover a surprising correspondence between a non-perturbative formulation of three-dimensional Lorentzian quantum gravity and a hermitian two-matrix model with ABAB-interaction. The gravitational transfer matrix can be expressed as the logarithm of a two-matrix integral, and we deduce from
International Nuclear Information System (INIS)
Ahn, Changrim; Nepomechie, Rafael I.; Suzuki, Junji
2008-01-01
Beisert et al. have identified an integrable SU(2,2) quantum spin chain which gives the one-loop anomalous dimensions of certain operators in large N c QCD. We derive a set of nonlinear integral equations (NLIEs) for this model, and compute the scattering matrix of the various (in particular, magnon) excitations
Lectures on matrix field theory
Ydri, Badis
2017-01-01
These lecture notes provide a systematic introduction to matrix models of quantum field theories with non-commutative and fuzzy geometries. The book initially focuses on the matrix formulation of non-commutative and fuzzy spaces, followed by a description of the non-perturbative treatment of the corresponding field theories. As an example, the phase structure of non-commutative phi-four theory is treated in great detail, with a separate chapter on the multitrace approach. The last chapter offers a general introduction to non-commutative gauge theories, while two appendices round out the text. Primarily written as a self-study guide for postgraduate students – with the aim of pedagogically introducing them to key analytical and numerical tools, as well as useful physical models in applications – these lecture notes will also benefit experienced researchers by providing a reference guide to the fundamentals of non-commutative field theory with an emphasis on matrix models and fuzzy geometries.
DEFF Research Database (Denmark)
Petersen, Kaare Brandt; Pedersen, Michael Syskind
Matrix identities, relations and approximations. A desktop reference for quick overview of mathematics of matrices.......Matrix identities, relations and approximations. A desktop reference for quick overview of mathematics of matrices....
Optimized Projection Matrix for Compressive Sensing
Directory of Open Access Journals (Sweden)
Jianping Xu
2010-01-01
Full Text Available Compressive sensing (CS is mainly concerned with low-coherence pairs, since the number of samples needed to recover the signal is proportional to the mutual coherence between projection matrix and sparsifying matrix. Until now, papers on CS always assume the projection matrix to be a random matrix. In this paper, aiming at minimizing the mutual coherence, a method is proposed to optimize the projection matrix. This method is based on equiangular tight frame (ETF design because an ETF has minimum coherence. It is impossible to solve the problem exactly because of the complexity. Therefore, an alternating minimization type method is used to find a feasible solution. The optimally designed projection matrix can further reduce the necessary number of samples for recovery or improve the recovery accuracy. The proposed method demonstrates better performance than conventional optimization methods, which brings benefits to both basis pursuit and orthogonal matching pursuit.
Farooque, Mohammad; Yuh, Chao-Yi
1996-01-01
A carbonate fuel cell matrix comprising support particles and crack attenuator particles which are made platelet in shape to increase the resistance of the matrix to through cracking. Also disclosed is a matrix having porous crack attenuator particles and a matrix whose crack attenuator particles have a thermal coefficient of expansion which is significantly different from that of the support particles, and a method of making platelet-shaped crack attenuator particles.
Matrix with Prescribed Eigenvectors
Ahmad, Faiz
2011-01-01
It is a routine matter for undergraduates to find eigenvalues and eigenvectors of a given matrix. But the converse problem of finding a matrix with prescribed eigenvalues and eigenvectors is rarely discussed in elementary texts on linear algebra. This problem is related to the "spectral" decomposition of a matrix and has important technical…
A J matrix engine for density functional theory calculations
International Nuclear Information System (INIS)
White, C.A.; Head-Gordon, M.
1996-01-01
We introduce a new method for the formation of the J matrix (Coulomb interaction matrix) within a basis of Cartesian Gaussian functions, as needed in density functional theory and Hartree endash Fock calculations. By summing the density matrix into the underlying Gaussian integral formulas, we have developed a J matrix open-quote open-quote engine close-quote close-quote which forms the exact J matrix without explicitly forming the full set of two electron integral intermediates. Several precomputable quantities have been identified, substantially reducing the number of floating point operations and memory accesses needed in a J matrix calculation. Initial timings indicate a speedup of greater than four times for the (pp parallel pp) class of integrals with speedups increasing to over ten times for (ff parallel ff) integrals. copyright 1996 American Institute of Physics
Knowledge strategies aiming to improve the intellectual capital of universities
Directory of Open Access Journals (Sweden)
Bejinaru Ruxandra
2017-09-01
Full Text Available The purpose of this paper is to present a new construct of the intellectual capital structure, based on the multifield theory of knowledge and the concept of nonlinear integrators and to identify the knowledge strategies to enhance the intellectual capital of universities. The paper presents a new approach, based on metaphorical thinking and thermodynamics logic in structuring the intellectual capital, based on the multifield theory of knowledge into its basic building blocks. Considering the two levels of intellectual capital, the paper presents the main knowledge strategies to enhance the university intellectual capital. The basic building blocks of the intellectual capital are: rational, emotional, and spiritual intellectual capital. Each building block is based on the corresponding field of knowledge. There are two significant levels of intellectual capital: potential and operational. Analyzing the university intellectual capital by using this new approach is much more realistic than in the previous approaches. The new approach is based on a thermodynamics paradigm, which means we need to develop new ways of thinking, evaluating, and enhancing the intellectual capital. The paper presents an original approach, based on metaphorical thinking, by considering basic ideas from the energy realm and thermodynamics theory. Also, the paper presents a matrix of possible knowledge strategies to increase the intellectual capital of universities.
The aim of psychoanalysis in theory and in practice.
Steiner, J
1996-12-01
The aims of psychoanalysis are reviewed in terms of theories of mental function and structure. The theory of mental conflict remains the central theory of classical psychoanalysis but has been deepened and supplemented by newer theories. In particular the theory of projective identification has radically altered our view of mental structure and function and has allowed us to reformulate the aims of psychoanalysis in terms of the re-acquisition and re-integration of projected parts of the self. The central role of mourning in this process is discussed, and some of the obstacles to progress are reviewed. It is suggested that oedipal resentments may play a central role in the creation of impasse.
High-dimensional statistical inference: From vector to matrix
Zhang, Anru
estimator is easy to implement via convex programming and performs well numerically. The techniques and main results developed in the chapter also have implications to other related statistical problems. An application to estimation of spiked covariance matrices from one-dimensional random projections is considered. The results demonstrate that it is still possible to accurately estimate the covariance matrix of a high-dimensional distribution based only on one-dimensional projections. For the third part of the thesis, we consider another setting of low-rank matrix completion. Current literature on matrix completion focuses primarily on independent sampling models under which the individual observed entries are sampled independently. Motivated by applications in genomic data integration, we propose a new framework of structured matrix completion (SMC) to treat structured missingness by design. Specifically, our proposed method aims at efficient matrix recovery when a subset of the rows and columns of an approximately low-rank matrix are observed. We provide theoretical justification for the proposed SMC method and derive lower bound for the estimation errors, which together establish the optimal rate of recovery over certain classes of approximately low-rank matrices. Simulation studies show that the method performs well in finite sample under a variety of configurations. The method is applied to integrate several ovarian cancer genomic studies with different extent of genomic measurements, which enables us to construct more accurate prediction rules for ovarian cancer survival.
Energy Technology Data Exchange (ETDEWEB)
John D. Bess
2009-03-01
The purpose of this research is to provide a fundamental computational investigation into the possible integration of experimental activities with the Advanced Test Reactor Critical (ATR-C) facility with the development of benchmark experiments. Criticality benchmarks performed in the ATR-C could provide integral data for key matrix and structural materials used in nuclear systems. Results would then be utilized in the improvement of nuclear data libraries and as a means for analytical methods validation. It is proposed that experiments consisting of well-characterized quantities of materials be placed in the Northwest flux trap position of the ATR-C. The reactivity worth of the material could be determined and computationally analyzed through comprehensive benchmark activities including uncertainty analyses. Experiments were modeled in the available benchmark model of the ATR using MCNP5 with the ENDF/B-VII.0 cross section library. A single bar (9.5 cm long, 0.5 cm wide, and 121.92 cm high) of each material could provide sufficient reactivity difference in the core geometry for computational modeling and analysis. However, to provide increased opportunity for the validation of computational models, additional bars of material placed in the flux trap would increase the effective reactivity up to a limit of 1$ insertion. For simplicity in assembly manufacture, approximately four bars of material could provide a means for additional experimental benchmark configurations, except in the case of strong neutron absorbers and many materials providing positive reactivity. Future tasks include the cost analysis and development of the experimental assemblies, including means for the characterization of the neutron flux and spectral indices. Oscillation techniques may also serve to provide additional means for experimentation and validation of computational methods and acquisition of integral data for improving neutron cross sections. Further assessment of oscillation
Energy Technology Data Exchange (ETDEWEB)
John D. Bess
2009-07-01
The purpose of this document is to identify some suggested types of experiments that can be performed in the Advanced Test Reactor Critical (ATR-C) facility. A fundamental computational investigation is provided to demonstrate possible integration of experimental activities in the ATR-C with the development of benchmark experiments. Criticality benchmarks performed in the ATR-C could provide integral data for key matrix and structural materials used in nuclear systems. Results would then be utilized in the improvement of nuclear data libraries and as a means for analytical methods validation. It is proposed that experiments consisting of well-characterized quantities of materials be placed in the Northwest flux trap position of the ATR-C. The reactivity worth of the material could be determined and computationally analyzed through comprehensive benchmark activities including uncertainty analyses. Experiments were modeled in the available benchmark model of the ATR using MCNP5 with the ENDF/B-VII.0 cross section library. A single bar (9.5 cm long, 0.5 cm wide, and 121.92 cm high) of each material could provide sufficient reactivity difference in the core geometry for computational modeling and analysis. However, to provide increased opportunity for the validation of computational models, additional bars of material placed in the flux trap would increase the effective reactivity up to a limit of 1$ insertion. For simplicity in assembly manufacture, approximately four bars of material could provide a means for additional experimental benchmark configurations, except in the case of strong neutron absorbers and many materials providing positive reactivity. Future tasks include the cost analysis and development of the experimental assemblies, including means for the characterization of the neutron flux and spectral indices. Oscillation techniques may also serve to provide additional means for experimentation and validation of computational methods and acquisition of
Directory of Open Access Journals (Sweden)
Marius PASCULEA
2013-06-01
Full Text Available Dialectics, multicultural matrix and exosomatism are three major ideas marginalized by the contemporary mainstream economic thinking. Nicholas Georgescu-Roegen, through the concept of bioeconomics, argumentatively defended epistemic pillars of economic science and elaborated a revolutionary paradigm based on the evolutional principle. This paper aims to integrate, in the UE approach of bioeconomics, the Romanian economist’s original vision, epistemology and methodology of economics.
Marius PASCULEA
2013-01-01
Dialectics, multicultural matrix and exosomatism are three major ideas marginalized by the contemporary mainstream economic thinking. Nicholas Georgescu-Roegen, through the concept of bioeconomics, argumentatively defended epistemic pillars of economic science and elaborated a revolutionary paradigm based on the evolutional principle. This paper aims to integrate, in the UE approach of bioeconomics, the Romanian economist’s original vision, epistemology and methodology of economics.
Oxysterol Restraint of Cholesterol Synthesis Prevents AIM2 Inflammasome Activation.
Dang, Eric V; McDonald, Jeffrey G; Russell, David W; Cyster, Jason G
2017-11-16
Type I interferon restrains interleukin-1β (IL-1β)-driven inflammation in macrophages by upregulating cholesterol-25-hydroxylase (Ch25h) and repressing SREBP transcription factors. However, the molecular links between lipid metabolism and IL-1β production remain obscure. Here, we demonstrate that production of 25-hydroxycholesterol (25-HC) by macrophages is required to prevent inflammasome activation by the DNA sensor protein absent in melanoma 2 (AIM2). We find that in response to bacterial infection or lipopolysaccharide (LPS) stimulation, macrophages upregulate Ch25h to maintain repression of SREBP2 activation and cholesterol synthesis. Increasing macrophage cholesterol content is sufficient to trigger IL-1β release in a crystal-independent but AIM2-dependent manner. Ch25h deficiency results in cholesterol-dependent reduced mitochondrial respiratory capacity and release of mitochondrial DNA into the cytosol. AIM2 deficiency rescues the increased inflammasome activity observed in Ch25h -/- . Therefore, activated macrophages utilize 25-HC in an anti-inflammatory circuit that maintains mitochondrial integrity and prevents spurious AIM2 inflammasome activation. Copyright © 2017 Elsevier Inc. All rights reserved.
A matrix model from string field theory
Directory of Open Access Journals (Sweden)
Syoji Zeze
2016-09-01
Full Text Available We demonstrate that a Hermitian matrix model can be derived from level truncated open string field theory with Chan-Paton factors. The Hermitian matrix is coupled with a scalar and U(N vectors which are responsible for the D-brane at the tachyon vacuum. Effective potential for the scalar is evaluated both for finite and large N. Increase of potential height is observed in both cases. The large $N$ matrix integral is identified with a system of N ZZ branes and a ghost FZZT brane.
Polychoric/Tetrachoric Matrix or Pearson Matrix? A methodological study
Directory of Open Access Journals (Sweden)
Dominguez Lara, Sergio Alexis
2014-04-01
Full Text Available The use of product-moment correlation of Pearson is common in most studies in factor analysis in psychology, but it is known that this statistic is only applicable when the variables related are in interval scale and normally distributed, and when are used in ordinal data may to produce a distorted correlation matrix . Thus is a suitable option using polychoric/tetrachoric matrices in item-level factor analysis when the items are in level measurement nominal or ordinal. The aim of this study was to show the differences in the KMO, Bartlett`s Test and Determinant of the Matrix, percentage of variance explained and factor loadings in depression trait scale of Depression Inventory Trait - State and the Neuroticism dimension of the short form of the Eysenck Personality Questionnaire -Revised, regarding the use of matrices polychoric/tetrachoric matrices and Pearson. These instruments was analyzed with different extraction methods (Maximum Likelihood, Minimum Rank Factor Analysis, Unweighted Least Squares and Principal Components, keeping constant the rotation method Promin were analyzed. Were observed differences regarding sample adequacy measures, as well as with respect to the explained variance and the factor loadings, for solutions having as polychoric/tetrachoric matrix. So it can be concluded that the polychoric / tetrachoric matrix give better results than Pearson matrices when it comes to item-level factor analysis using different methods.
Parallelism in matrix computations
Gallopoulos, Efstratios; Sameh, Ahmed H
2016-01-01
This book is primarily intended as a research monograph that could also be used in graduate courses for the design of parallel algorithms in matrix computations. It assumes general but not extensive knowledge of numerical linear algebra, parallel architectures, and parallel programming paradigms. The book consists of four parts: (I) Basics; (II) Dense and Special Matrix Computations; (III) Sparse Matrix Computations; and (IV) Matrix functions and characteristics. Part I deals with parallel programming paradigms and fundamental kernels, including reordering schemes for sparse matrices. Part II is devoted to dense matrix computations such as parallel algorithms for solving linear systems, linear least squares, the symmetric algebraic eigenvalue problem, and the singular-value decomposition. It also deals with the development of parallel algorithms for special linear systems such as banded ,Vandermonde ,Toeplitz ,and block Toeplitz systems. Part III addresses sparse matrix computations: (a) the development of pa...
International Nuclear Information System (INIS)
Strobel, E.L.
1985-01-01
Given the many conflicting experimental results, examination is made of the neutrino mass matrix in order to determine possible masses and mixings. It is assumed that the Dirac mass matrix for the electron, muon, and tau neutrinos is similar in form to those of the quarks and charged leptons, and that the smallness of the observed neutrino masses results from the Gell-Mann-Ramond-Slansky mechanism. Analysis of masses and mixings for the neutrinos is performed using general structures for the Majorana mass matrix. It is shown that if certain tentative experimental results concerning the neutrino masses and mixing angles are confirmed, significant limitations may be placed on the Majorana mass matrix. The most satisfactory simple assumption concerning the Majorana mass matrix is that it is approximately proportional to the Dirac mass matrix. A very recent experimental neutrino mass result and its implications are discussed. Some general properties of matrices with structure similar to the Dirac mass matrices are discussed
Concept for Energy Security Matrix
International Nuclear Information System (INIS)
Kisel, Einari; Hamburg, Arvi; Härm, Mihkel; Leppiman, Ando; Ots, Märt
2016-01-01
The following paper presents a discussion of short- and long-term energy security assessment methods and indicators. The aim of the current paper is to describe diversity of approaches to energy security, to structure energy security indicators used by different institutions and papers, and to discuss several indicators that also play important role in the design of energy policy of a state. Based on this analysis the paper presents a novel Energy Security Matrix that structures relevant energy security indicators from the aspects of Technical Resilience and Vulnerability, Economic Dependence and Political Affectability for electricity, heat and transport fuel sectors. Earlier publications by different authors have presented energy security assessment methodologies that use publicly available indicators from different databases. Current paper challenges viability of some of these indicators and introduces new indicators that would deliver stronger energy security policy assessments. Energy Security Matrix and its indicators are based on experiences that the authors have gathered as high-level energy policymakers in Estonia, where all different aspects of energy security can be observed. - Highlights: •Energy security should be analysed in technical, economic and political terms; •Energy Security Matrix provides a framework for energy security analyses; •Applicability of Matrix is limited due to the lack of statistical data and sensitivity of output.
Cai, Minggang; Lin, Yan; Chen, Meng; Yang, Weifeng; Du, Huihong; Xu, Ye; Cheng, Shayen; Xu, Fangjian; Hong, Jiajun; Chen, Mian; Ke, Hongwei
2017-12-31
To obtain the historical changes of pyrogenic sources, integrated source apportionment methods, which include PAH compositions, diagnostic ratios (DRs), Pb isotopic ratios, and positive matrix factorization (PMF) model, were developed and applied in sediments of the northern South China Sea. These methods provided a gradually clear picture of energy structural change. Spatially, Σ 15 PAH (11.3 to 95.5ng/g) and Pb (10.2 to 74.6μg/g) generally exhibited decreasing concentration gradient offshore; while the highest levels of PAHs and Pb were observed near the southern Taiwan Strait, which may be induced by accumulation of different fluvial input. Historical records of pollutants followed closely with the economic development of China, with fast growth of Σ 15 PAH and Pb occurring since the 1980s and 1990s, respectively. The phasing-out of leaded gasoline in China was captured with a sharp decrease of Pb after the mid-1990s. PAHs and Pb correlated well with TOC and clay content for core sediments, which was not observed for surface sediments. There was an up-core increase of high molecular PAH proportions. Coal and biomass burning were then qualitatively identified as the major sources of PAHs with DRs. Furthermore, shift toward less radiogenic signatures of Pb isotopic ratios after 1900 revealed the start and growing importance of industrial sources. Finally, a greater separation and quantification of various input was achieved by a three-factor PMF model, which made it clear that biomass burning, coal combustion, and vehicle emissions accounted for 40±20%, 41±13%, and 19±12% of PAHs through the core. Biomass and coal combustion acted as major sources before 2000, while contributions from vehicle emission soared thereafter. The integrated multi-methodologies here improved the source apportionment by reducing biases with a step-down and cross-validation perspective, which could be similarly applied to other aquatic systems. Copyright © 2017 Elsevier B.V. All
Ferreira, Rosana Gomes; Monteiro, Mychelle Alves; Pereira, Mararlene Ulberg; da Costa, Rafaela Pinto; Spisso, Bernardete Ferraz; Calado, Veronica
2016-08-01
The aim of this work was to study the feasibility of producing an egg matrix candidate reference material for salinomycin. Preservation techniques investigated were freeze-drying and spray drying dehydration. Homogeneity and stability studies of the produced batches were conducted according to ISO Guides 34 and 35. The results showed that all produced batches were homogeneous and both freeze-drying and spray drying techniques were suitable for matrix dehydrating, ensuring the material stability. In order to preserve the material integrity, it must be transported within the temperature range of -20 up to 25°C. The results constitute an important step towards the development of an egg matrix reference material for salinomycin is possible. Copyright © 2016 Elsevier B.V. All rights reserved.
DEFF Research Database (Denmark)
Hansen, Kristoffer Arnsfelt; Ibsen-Jensen, Rasmus; Podolskii, Vladimir V.
2013-01-01
For matrix games we study how small nonzero probability must be used in optimal strategies. We show that for image win–lose–draw games (i.e. image matrix games) nonzero probabilities smaller than image are never needed. We also construct an explicit image win–lose game such that the unique optimal...
DEFF Research Database (Denmark)
Schneider, Jesper Wiborg; Borlund, Pia
2007-01-01
The present two-part article introduces matrix comparison as a formal means for evaluation purposes in informetric studies such as cocitation analysis. In the first part, the motivation behind introducing matrix comparison to informetric studies, as well as two important issues influencing such c...
Saleem, M
2002-01-01
The Unitarity of the CKM matrix is examined in the light of the latest available accurate data. The analysis shows that a conclusive result cannot be derived at present. Only more precise data can determine whether the CKM matrix opens new vistas beyond the standard model or not.
Vertical Integration in the Taiwan Aquaculture Industry
Tzong-Ru Lee (Jiun-Shen); Yi-Hsu; Cheng-Jen Lin; Kongkiti Phusavat; Nirote Sinnarong
2011-01-01
The study aims to improve the distribution channels in the Taiwan aquaculture industry through a better vertical integration. This study is derived from a need to improve the distribution performance of agricultural-based industries in response to increasing food demands in Asia and elsewhere. Based on a four-by-eight matrix derived from both a value chain and a service profit chain, thirty different strategies are developed. This development is based on key success factors and strategies for...
International Nuclear Information System (INIS)
Markowski, Adam S.; Mannan, M. Sam
2008-01-01
A risk matrix is a mechanism to characterize and rank process risks that are typically identified through one or more multifunctional reviews (e.g., process hazard analysis, audits, or incident investigation). This paper describes a procedure for developing a fuzzy risk matrix that may be used for emerging fuzzy logic applications in different safety analyses (e.g., LOPA). The fuzzification of frequency and severity of the consequences of the incident scenario are described which are basic inputs for fuzzy risk matrix. Subsequently using different design of risk matrix, fuzzy rules are established enabling the development of fuzzy risk matrices. Three types of fuzzy risk matrix have been developed (low-cost, standard, and high-cost), and using a distillation column case study, the effect of the design on final defuzzified risk index is demonstrated
International Nuclear Information System (INIS)
Baron, Jorge H.; Rivera, S.S.
2000-01-01
The so-called vulnerability matrix is used in the evaluation part of the probabilistic safety assessment for a nuclear power plant, during the containment event trees calculations. This matrix is established from what is knows as Numerical Categories for Engineering Judgement. This matrix is usually established with numerical values obtained with traditional arithmetic using the set theory. The representation of this matrix with fuzzy numbers is much more adequate, due to the fact that the Numerical Categories for Engineering Judgement are better represented with linguistic variables, such as 'highly probable', 'probable', 'impossible', etc. In the present paper a methodology to obtain a Fuzzy Vulnerability Matrix is presented, starting from the recommendations on the Numerical Categories for Engineering Judgement. (author)
On renormalization group flow in matrix model
International Nuclear Information System (INIS)
Gao, H.B.
1992-10-01
The renormalization group flow recently found by Brezin and Zinn-Justin by integrating out redundant entries of the (N+1)x(N+1) Hermitian random matrix is studied. By introducing explicitly the RG flow parameter, and adding suitable counter terms to the matrix potential of the one matrix model, we deduce some interesting properties of the RG trajectories. In particular, the string equation for the general massive model interpolating between the UV and IR fixed points turns out to be a consequence of RG flow. An ambiguity in the UV region of the RG trajectory is remarked to be related to the large order behaviour of the one matrix model. (author). 7 refs
Program for accident and incident management support, AIMS
International Nuclear Information System (INIS)
Putra, M.A.
1993-12-01
A prototype of an advisory computer program is presented which could be used in monitoring and analyzing an ongoing incident in a nuclear power plant. The advisory computer program, called the Accident and Incident Management Support (AIMS), focuses on processing a set of data that is to be transmitted from a nuclear power plant to a national or regional emergency center during an incident. The AIMS program will assess the reactor conditions by processing the measured plant parameters. The applied model of the power plant contains a level of complexity that is comparable with the simplified plant model that the power plant operator uses. A standardized decay heat function and a steam water property library is used in the integral balance equations for mass and energy. A simulation of the station blackout accident of the Borssele plant is used to test the program. The program predicts successively: (1) the time of dryout of the steam generators, (2) the time of saturation of the primary system, and (3) the onset of core uncovery. The coolant system with the actual water levels will be displayed on the screen. (orig./HP)
International Nuclear Information System (INIS)
Krenciglowa, E.M.; Kung, C.L.; Kuo, T.T.S.; Osnes, E.; and Department of Physics, State University of New York at Stony Brook, Stony Brook, New York 11794)
1976-01-01
Different definitions of the reaction matrix G appropriate to the calculation of nuclear structure are reviewed and discussed. Qualitative physical arguments are presented in support of a two-step calculation of the G-matrix for finite nuclei. In the first step the high-energy excitations are included using orthogonalized plane-wave intermediate states, and in the second step the low-energy excitations are added in, using harmonic oscillator intermediate states. Accurate calculations of G-matrix elements for nuclear structure calculations in the Aapprox. =18 region are performed following this procedure and treating the Pauli exclusion operator Q 2 /sub p/ by the method of Tsai and Kuo. The treatment of Q 2 /sub p/, the effect of the intermediate-state spectrum and the energy dependence of the reaction matrix are investigated in detail. The present matrix elements are compared with various matrix elements given in the literature. In particular, close agreement is obtained with the matrix elements calculated by Kuo and Brown using approximate methods
Matrix Metalloproteinase Enzyme Family
Directory of Open Access Journals (Sweden)
Ozlem Goruroglu Ozturk
2013-04-01
Full Text Available Matrix metalloproteinases play an important role in many biological processes such as embriogenesis, tissue remodeling, wound healing, and angiogenesis, and in some pathological conditions such as atherosclerosis, arthritis and cancer. Currently, 24 genes have been identified in humans that encode different groups of matrix metalloproteinase enzymes. This review discuss the members of the matrix metalloproteinase family and their substrate specificity, structure, function and the regulation of their enzyme activity by tissue inhibitors. [Archives Medical Review Journal 2013; 22(2.000: 209-220
Matrix groups for undergraduates
Tapp, Kristopher
2005-01-01
Matrix groups touch an enormous spectrum of the mathematical arena. This textbook brings them into the undergraduate curriculum. It makes an excellent one-semester course for students familiar with linear and abstract algebra and prepares them for a graduate course on Lie groups. Matrix Groups for Undergraduates is concrete and example-driven, with geometric motivation and rigorous proofs. The story begins and ends with the rotations of a globe. In between, the author combines rigor and intuition to describe basic objects of Lie theory: Lie algebras, matrix exponentiation, Lie brackets, and maximal tori.
Eves, Howard
1980-01-01
The usefulness of matrix theory as a tool in disciplines ranging from quantum mechanics to psychometrics is widely recognized, and courses in matrix theory are increasingly a standard part of the undergraduate curriculum.This outstanding text offers an unusual introduction to matrix theory at the undergraduate level. Unlike most texts dealing with the topic, which tend to remain on an abstract level, Dr. Eves' book employs a concrete elementary approach, avoiding abstraction until the final chapter. This practical method renders the text especially accessible to students of physics, engineeri
Application of FIRE for the calculation of photon matrix elements
Indian Academy of Sciences (India)
to evaluate the two-loop Feynman diagrams for the photon matrix element of the ... sum of scalar Feynman integrals to a linear combination of a few master integrals. .... Then, FIRE is used to express these scalar integrals as a linear combi-.
Czerwinski, Michael; Spence, Jason R
2017-01-05
Recently in Nature, Gjorevski et al. (2016) describe a fully defined synthetic hydrogel that mimics the extracellular matrix to support in vitro growth of intestinal stem cells and organoids. The hydrogel allows exquisite control over the chemical and physical in vitro niche and enables identification of regulatory properties of the matrix. Copyright © 2017 Elsevier Inc. All rights reserved.
The Matrix Organization Revisited
DEFF Research Database (Denmark)
Gattiker, Urs E.; Ulhøi, John Parm
1999-01-01
This paper gives a short overview of matrix structure and technology management. It outlines some of the characteristics and also points out that many organizations may actualy be hybrids (i.e. mix several ways of organizing to allocate resorces effectively).......This paper gives a short overview of matrix structure and technology management. It outlines some of the characteristics and also points out that many organizations may actualy be hybrids (i.e. mix several ways of organizing to allocate resorces effectively)....
Koo, H.; Falsetta, M.L.; Klein, M.I.
2013-01-01
Many infectious diseases in humans are caused or exacerbated by biofilms. Dental caries is a prime example of a biofilm-dependent disease, resulting from interactions of microorganisms, host factors, and diet (sugars), which modulate the dynamic formation of biofilms on tooth surfaces. All biofilms have a microbial-derived extracellular matrix as an essential constituent. The exopolysaccharides formed through interactions between sucrose- (and starch-) and Streptococcus mutans-derived exoenzymes present in the pellicle and on microbial surfaces (including non-mutans) provide binding sites for cariogenic and other organisms. The polymers formed in situ enmesh the microorganisms while forming a matrix facilitating the assembly of three-dimensional (3D) multicellular structures that encompass a series of microenvironments and are firmly attached to teeth. The metabolic activity of microbes embedded in this exopolysaccharide-rich and diffusion-limiting matrix leads to acidification of the milieu and, eventually, acid-dissolution of enamel. Here, we discuss recent advances concerning spatio-temporal development of the exopolysaccharide matrix and its essential role in the pathogenesis of dental caries. We focus on how the matrix serves as a 3D scaffold for biofilm assembly while creating spatial heterogeneities and low-pH microenvironments/niches. Further understanding on how the matrix modulates microbial activity and virulence expression could lead to new approaches to control cariogenic biofilms. PMID:24045647
Integrable boundary conditions and modified Lax equations
International Nuclear Information System (INIS)
Avan, Jean; Doikou, Anastasia
2008-01-01
We consider integrable boundary conditions for both discrete and continuum classical integrable models. Local integrals of motion generated by the corresponding 'transfer' matrices give rise to time evolution equations for the initial Lax operator. We systematically identify the modified Lax pairs for both discrete and continuum boundary integrable models, depending on the classical r-matrix and the boundary matrix
Redesigning Triangular Dense Matrix Computations on GPUs
Charara, Ali
2016-08-09
A new implementation of the triangular matrix-matrix multiplication (TRMM) and the triangular solve (TRSM) kernels are described on GPU hardware accelerators. Although part of the Level 3 BLAS family, these highly computationally intensive kernels fail to achieve the percentage of the theoretical peak performance on GPUs that one would expect when running kernels with similar surface-to-volume ratio on hardware accelerators, i.e., the standard matrix-matrix multiplication (GEMM). The authors propose adopting a recursive formulation, which enriches the TRMM and TRSM inner structures with GEMM calls and, therefore, reduces memory traffic while increasing the level of concurrency. The new implementation enables efficient use of the GPU memory hierarchy and mitigates the latency overhead, to run at the speed of the higher cache levels. Performance comparisons show up to eightfold and twofold speedups for large dense matrix sizes, against the existing state-of-the-art TRMM and TRSM implementations from NVIDIA cuBLAS, respectively, across various GPU generations. Once integrated into high-level Cholesky-based dense linear algebra algorithms, the performance impact on the overall applications demonstrates up to fourfold and twofold speedups, against the equivalent native implementations, linked with cuBLAS TRMM and TRSM kernels, respectively. The new TRMM/TRSM kernel implementations are part of the open-source KBLAS software library (http://ecrc.kaust.edu.sa/Pages/Res-kblas.aspx) and are lined up for integration into the NVIDIA cuBLAS library in the upcoming v8.0 release.
Containment Code Validation Matrix
International Nuclear Information System (INIS)
Chin, Yu-Shan; Mathew, P.M.; Glowa, Glenn; Dickson, Ray; Liang, Zhe; Leitch, Brian; Barber, Duncan; Vasic, Aleks; Bentaib, Ahmed; Journeau, Christophe; Malet, Jeanne; Studer, Etienne; Meynet, Nicolas; Piluso, Pascal; Gelain, Thomas; Michielsen, Nathalie; Peillon, Samuel; Porcheron, Emmanuel; Albiol, Thierry; Clement, Bernard; Sonnenkalb, Martin; Klein-Hessling, Walter; Arndt, Siegfried; Weber, Gunter; Yanez, Jorge; Kotchourko, Alexei; Kuznetsov, Mike; Sangiorgi, Marco; Fontanet, Joan; Herranz, Luis; Garcia De La Rua, Carmen; Santiago, Aleza Enciso; Andreani, Michele; Paladino, Domenico; Dreier, Joerg; Lee, Richard; Amri, Abdallah
2014-01-01
The Committee on the Safety of Nuclear Installations (CSNI) formed the CCVM (Containment Code Validation Matrix) task group in 2002. The objective of this group was to define a basic set of available experiments for code validation, covering the range of containment (ex-vessel) phenomena expected in the course of light and heavy water reactor design basis accidents and beyond design basis accidents/severe accidents. It was to consider phenomena relevant to pressurised heavy water reactor (PHWR), pressurised water reactor (PWR) and boiling water reactor (BWR) designs of Western origin as well as of Eastern European VVER types. This work would complement the two existing CSNI validation matrices for thermal hydraulic code validation (NEA/CSNI/R(1993)14) and In-vessel core degradation (NEA/CSNI/R(2001)21). The report initially provides a brief overview of the main features of a PWR, BWR, CANDU and VVER reactors. It also provides an overview of the ex-vessel corium retention (core catcher). It then provides a general overview of the accident progression for light water and heavy water reactors. The main focus is to capture most of the phenomena and safety systems employed in these reactor types and to highlight the differences. This CCVM contains a description of 127 phenomena, broken down into 6 categories: - Containment Thermal-hydraulics Phenomena; - Hydrogen Behaviour (Combustion, Mitigation and Generation) Phenomena; - Aerosol and Fission Product Behaviour Phenomena; - Iodine Chemistry Phenomena; - Core Melt Distribution and Behaviour in Containment Phenomena; - Systems Phenomena. A synopsis is provided for each phenomenon, including a description, references for further information, significance for DBA and SA/BDBA and a list of experiments that may be used for code validation. The report identified 213 experiments, broken down into the same six categories (as done for the phenomena). An experiment synopsis is provided for each test. Along with a test description
International Nuclear Information System (INIS)
Itzykson, C.
1992-01-01
Some mathematical results are described on a remarkable application of matrix interaction due to Witten and Kontsevich, to study topological invariants. Some interesting properties of the Kontsevich integrals are identified. (K.A.) 4 refs
A real-space stochastic density matrix approach for density functional electronic structure.
Beck, Thomas L
2015-12-21
The recent development of real-space grid methods has led to more efficient, accurate, and adaptable approaches for large-scale electrostatics and density functional electronic structure modeling. With the incorporation of multiscale techniques, linear-scaling real-space solvers are possible for density functional problems if localized orbitals are used to represent the Kohn-Sham energy functional. These methods still suffer from high computational and storage overheads, however, due to extensive matrix operations related to the underlying wave function grid representation. In this paper, an alternative stochastic method is outlined that aims to solve directly for the one-electron density matrix in real space. In order to illustrate aspects of the method, model calculations are performed for simple one-dimensional problems that display some features of the more general problem, such as spatial nodes in the density matrix. This orbital-free approach may prove helpful considering a future involving increasingly parallel computing architectures. Its primary advantage is the near-locality of the random walks, allowing for simultaneous updates of the density matrix in different regions of space partitioned across the processors. In addition, it allows for testing and enforcement of the particle number and idempotency constraints through stabilization of a Feynman-Kac functional integral as opposed to the extensive matrix operations in traditional approaches.
Hierarchical matrix techniques for the solution of elliptic equations
Chá vez, Gustavo; Turkiyyah, George; Yokota, Rio; Keyes, David E.
2014-01-01
Hierarchical matrix approximations are a promising tool for approximating low-rank matrices given the compactness of their representation and the economy of the operations between them. Integral and differential operators have been the major
Immobilization of industrial waste in cement–bentonite clay matrix
Indian Academy of Sciences (India)
Unknown
Immobilization of industrial waste in cement–bentonite clay matrix. I B PLECAS* and S ... high structural integrity and minimizing the risk of escape by leaching. ..... Radioactive Waste Management and Nuclear Fuel Cycle 14. 195. Plecas I ...
Matrix method for acoustic levitation simulation.
Andrade, Marco A B; Perez, Nicolas; Buiochi, Flavio; Adamowski, Julio C
2011-08-01
A matrix method is presented for simulating acoustic levitators. A typical acoustic levitator consists of an ultrasonic transducer and a reflector. The matrix method is used to determine the potential for acoustic radiation force that acts on a small sphere in the standing wave field produced by the levitator. The method is based on the Rayleigh integral and it takes into account the multiple reflections that occur between the transducer and the reflector. The potential for acoustic radiation force obtained by the matrix method is validated by comparing the matrix method results with those obtained by the finite element method when using an axisymmetric model of a single-axis acoustic levitator. After validation, the method is applied in the simulation of a noncontact manipulation system consisting of two 37.9-kHz Langevin-type transducers and a plane reflector. The manipulation system allows control of the horizontal position of a small levitated sphere from -6 mm to 6 mm, which is done by changing the phase difference between the two transducers. The horizontal position of the sphere predicted by the matrix method agrees with the horizontal positions measured experimentally with a charge-coupled device camera. The main advantage of the matrix method is that it allows simulation of non-symmetric acoustic levitators without requiring much computational effort.
Salient Object Detection via Structured Matrix Decomposition.
Peng, Houwen; Li, Bing; Ling, Haibin; Hu, Weiming; Xiong, Weihua; Maybank, Stephen J
2016-05-04
Low-rank recovery models have shown potential for salient object detection, where a matrix is decomposed into a low-rank matrix representing image background and a sparse matrix identifying salient objects. Two deficiencies, however, still exist. First, previous work typically assumes the elements in the sparse matrix are mutually independent, ignoring the spatial and pattern relations of image regions. Second, when the low-rank and sparse matrices are relatively coherent, e.g., when there are similarities between the salient objects and background or when the background is complicated, it is difficult for previous models to disentangle them. To address these problems, we propose a novel structured matrix decomposition model with two structural regularizations: (1) a tree-structured sparsity-inducing regularization that captures the image structure and enforces patches from the same object to have similar saliency values, and (2) a Laplacian regularization that enlarges the gaps between salient objects and the background in feature space. Furthermore, high-level priors are integrated to guide the matrix decomposition and boost the detection. We evaluate our model for salient object detection on five challenging datasets including single object, multiple objects and complex scene images, and show competitive results as compared with 24 state-of-the-art methods in terms of seven performance metrics.
Analytical solutions to matrix diffusion problems
Energy Technology Data Exchange (ETDEWEB)
Kekäläinen, Pekka, E-mail: pekka.kekalainen@helsinki.fi [Laboratory of Radiochemistry, Department of Chemistry, P.O. Box 55, FIN-00014 University of Helsinki (Finland)
2014-10-06
We report an analytical method to solve in a few cases of practical interest the equations which have traditionally been proposed for the matrix diffusion problem. In matrix diffusion, elements dissolved in ground water can penetrate the porous rock surronuding the advective flow paths. In the context of radioactive waste repositories this phenomenon provides a mechanism by which the area of rock surface in contact with advecting elements is greatly enhanced, and can thus be an important delay mechanism. The cases solved are relevant for laboratory as well for in situ experiments. Solutions are given as integral representations well suited for easy numerical solution.
A random matrix model of relaxation
International Nuclear Information System (INIS)
Lebowitz, J L; Pastur, L
2004-01-01
We consider a two-level system, S 2 , coupled to a general n level system, S n , via a random matrix. We derive an integral representation for the mean reduced density matrix ρ(t) of S 2 in the limit n → ∞, and we identify a model of S n which possesses some of the properties expected for macroscopic thermal reservoirs. In particular, it yields the Gibbs form for ρ(∞). We also consider an analog of the van Hove limit and obtain a master equation (Markov dynamics) for the evolution of ρ(t) on an appropriate time scale
Two-matrix models and c =1 string theory
International Nuclear Information System (INIS)
Bonora, L.; Xiong Chuansheng
1994-05-01
We show that the most general two-matrix model with bilinear coupling underlies c = 1 string theory. More precisely we prove that W 1+∞ constraints, a subset of the correlation functions and the integrable hierarchy characterizing such two-matrix model, correspond exactly to the W 1+∞ constraints, to the discrete tachyon correlation functions and the integrable hierarchy of the c = 1 string theory. (orig.)
Bhatia, Rajendra
2013-01-01
This book is an outcome of the Indo-French Workshop on Matrix Information Geometries (MIG): Applications in Sensor and Cognitive Systems Engineering, which was held in Ecole Polytechnique and Thales Research and Technology Center, Palaiseau, France, in February 23-25, 2011. The workshop was generously funded by the Indo-French Centre for the Promotion of Advanced Research (IFCPAR). During the event, 22 renowned invited french or indian speakers gave lectures on their areas of expertise within the field of matrix analysis or processing. From these talks, a total of 17 original contribution or state-of-the-art chapters have been assembled in this volume. All articles were thoroughly peer-reviewed and improved, according to the suggestions of the international referees. The 17 contributions presented are organized in three parts: (1) State-of-the-art surveys & original matrix theory work, (2) Advanced matrix theory for radar processing, and (3) Matrix-based signal processing applications.
Characterization of organic matrix extracted from fresh water pearls
International Nuclear Information System (INIS)
Ma Yufei; Gao Yonghua; Feng Qingling
2011-01-01
Aragonite pearl and vaterite pearl from cultured Hyriopsis cumingii in Zhuji (Zhejiang province, China) were chosen for the study. The matrix proteins were extracted using water and weak acid, and classified as water soluble matrix (WSM), acid soluble matrix (ASM) and acid insoluble matrix (AIM). The proteins from both pearls were characterized by sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE), X-ray diffraction (XRD) and Fourier transformation infrared spectra (FTIR). The results showed that, AIM of aragonite pearl and vaterite pearl had an ordered structure of α-helix. ASM conformations of these two pearls were different from each other. WSM differed the most between these two pearls. - Research Highlights: → We use a specific method for extracting matrix proteins from aragonite pearl and vaterite pearl respectively. → The matrix proteins are extracted by water and weak acid, and classified as water soluble matrix (WSM), acid soluble matrix (ASM) and acid insoluble matrix (AIM). → AIM of aragonite pearl and vaterite pearl have an ordered structure. ASM conformations of the two pearls are different from each other. WSM differ the most between these two pearls.
Nam, Kwangwoo; Sakai, Yuuki; Funamoto, Seiichi; Kimura, Tsuyoshi; Kishida, Akio
2011-01-01
In this study, we aimed to replicate the function of native tissues that can be used in tissue engineering and regenerative medicine. The key to such replication is the preparation of an artificial collagen matrix that possesses a structure resembling that of the extracellular matrix. We, therefore, prepared a collagen matrix by fibrillogenesis in a NaCl/Na(2)HPO(4) aqueous solution using a dialysis cassette and investigated its biological behavior in vitro and in vivo. The in vitro cell adhesion and proliferation did not show any significant differences. The degradation rate in the living body could be controlled according to the preparation condition, where the collagen matrix with high water content (F-collagen matrix, >98%) showed fast degradation and collagen matrix with lower water content (T-collagen matrix, >80%) showed no degradation for 8 weeks. The degradation did not affect the inflammatory response at all and relatively faster wound healing response was observed. Comparing this result with that of collagen gel and decellularized cornea, it can be concluded that the structural factor is very important and no cell abnormal behavior would be observed for quaternary structured collagen matrix.
Praeger, Cheryl; Tao, Terence
2018-01-01
MATRIX is Australia’s international, residential mathematical research institute. It facilitates new collaborations and mathematical advances through intensive residential research programs, each lasting 1-4 weeks. This book is a scientific record of the five programs held at MATRIX in its first year, 2016: Higher Structures in Geometry and Physics (Chapters 1-5 and 18-21); Winter of Disconnectedness (Chapter 6 and 22-26); Approximation and Optimisation (Chapters 7-8); Refining C*-Algebraic Invariants for Dynamics using KK-theory (Chapters 9-13); Interactions between Topological Recursion, Modularity, Quantum Invariants and Low-dimensional Topology (Chapters 14-17 and 27). The MATRIX Scientific Committee selected these programs based on their scientific excellence and the participation rate of high-profile international participants. Each program included ample unstructured time to encourage collaborative research; some of the longer programs also included an embedded conference or lecture series. The artic...
Energy Technology Data Exchange (ETDEWEB)
Pan, Feng [Los Alamos National Laboratory; Kasiviswanathan, Shiva [Los Alamos National Laboratory
2010-01-01
In the matrix interdiction problem, a real-valued matrix and an integer k is given. The objective is to remove k columns such that the sum over all rows of the maximum entry in each row is minimized. This combinatorial problem is closely related to bipartite network interdiction problem which can be applied to prioritize the border checkpoints in order to minimize the probability that an adversary can successfully cross the border. After introducing the matrix interdiction problem, we will prove the problem is NP-hard, and even NP-hard to approximate with an additive n{gamma} factor for a fixed constant {gamma}. We also present an algorithm for this problem that achieves a factor of (n-k) mUltiplicative approximation ratio.
DEFF Research Database (Denmark)
Frandsen, Gudmund Skovbjerg; Frandsen, Peter Frands
2009-01-01
We consider maintaining information about the rank of a matrix under changes of the entries. For n×n matrices, we show an upper bound of O(n1.575) arithmetic operations and a lower bound of Ω(n) arithmetic operations per element change. The upper bound is valid when changing up to O(n0.575) entries...... in a single column of the matrix. We also give an algorithm that maintains the rank using O(n2) arithmetic operations per rank one update. These bounds appear to be the first nontrivial bounds for the problem. The upper bounds are valid for arbitrary fields, whereas the lower bound is valid for algebraically...... closed fields. The upper bound for element updates uses fast rectangular matrix multiplication, and the lower bound involves further development of an earlier technique for proving lower bounds for dynamic computation of rational functions....
Pérez López, César
2014-01-01
MATLAB is a high-level language and environment for numerical computation, visualization, and programming. Using MATLAB, you can analyze data, develop algorithms, and create models and applications. The language, tools, and built-in math functions enable you to explore multiple approaches and reach a solution faster than with spreadsheets or traditional programming languages, such as C/C++ or Java. MATLAB Matrix Algebra introduces you to the MATLAB language with practical hands-on instructions and results, allowing you to quickly achieve your goals. Starting with a look at symbolic and numeric variables, with an emphasis on vector and matrix variables, you will go on to examine functions and operations that support vectors and matrices as arguments, including those based on analytic parent functions. Computational methods for finding eigenvalues and eigenvectors of matrices are detailed, leading to various matrix decompositions. Applications such as change of bases, the classification of quadratic forms and ...
Hohn, Franz E
2012-01-01
This complete and coherent exposition, complemented by numerous illustrative examples, offers readers a text that can teach by itself. Fully rigorous in its treatment, it offers a mathematically sound sequencing of topics. The work starts with the most basic laws of matrix algebra and progresses to the sweep-out process for obtaining the complete solution of any given system of linear equations - homogeneous or nonhomogeneous - and the role of matrix algebra in the presentation of useful geometric ideas, techniques, and terminology.Other subjects include the complete treatment of the structur
International Nuclear Information System (INIS)
Brown, T.W.
2010-11-01
The same complex matrix model calculates both tachyon scattering for the c=1 non-critical string at the self-dual radius and certain correlation functions of half-BPS operators in N=4 super- Yang-Mills. It is dual to another complex matrix model where the couplings of the first model are encoded in the Kontsevich-like variables of the second. The duality between the theories is mirrored by the duality of their Feynman diagrams. Analogously to the Hermitian Kontsevich- Penner model, the correlation functions of the second model can be written as sums over discrete points in subspaces of the moduli space of punctured Riemann surfaces. (orig.)
Energy Technology Data Exchange (ETDEWEB)
Brown, T.W.
2010-11-15
The same complex matrix model calculates both tachyon scattering for the c=1 non-critical string at the self-dual radius and certain correlation functions of half-BPS operators in N=4 super- Yang-Mills. It is dual to another complex matrix model where the couplings of the first model are encoded in the Kontsevich-like variables of the second. The duality between the theories is mirrored by the duality of their Feynman diagrams. Analogously to the Hermitian Kontsevich- Penner model, the correlation functions of the second model can be written as sums over discrete points in subspaces of the moduli space of punctured Riemann surfaces. (orig.)
TURKISH SOCIAL ACCOUNTING MATRIX FOR 1996
ASLAN, MURAT
2015-01-01
This study is aimed at constructing detail social accounting matrix (SAM) for Turkey by using the most recent available data. In order to reconcile the inconsistency in data which are gathered from various official institutions, the study employs Cross Entropy method
DEFF Research Database (Denmark)
Axelsson, Runo
2013-01-01
Background: In Sweden, as in many other countries, there has been a succession of trends in the organisation of health care and other welfare services. These trends have had different implications for the integration of services in the health and welfare system. Aims: One aim is to discuss...... the implications of different organisational trends for the integration of health and welfare services. Another aim is to introduce a Swedish model of financial coordination as a flexible way to organise integration. Organisational trends: In the 1960’s there was an expansion of health and welfare services leading...... an increasing lack of integration in the health and welfare system. In the 2000’s, there has been a re-centralisation through mergers of hospitals, regions and state agencies. It has become clear, however, that mergers do not promote integration but rather increase the bureaucratisation of the system. Model...
Construction of a narrative network aimed at implementing inclusive processes
Directory of Open Access Journals (Sweden)
Francesca Salis
2017-01-01
Full Text Available The concept of inclusion in its complex aspects aimed at overcoming barriers to learning and involvement has led this research in university, in the light of special pedagogy and didactics, on the basis of inclusion index parameters, detecting the levels of integrated planning with the territory. The purpose of this study is not limited to disability and to special education needs but goes further than that encompassing isolation and/or exclusions. As far as the university system is concerned, it becomes significant to enquire about the inclusion process, in this case by means of a narrative approach, bearing in mind that organizational and learning models, together with access modes may give rise to social exclusion.Università e territorio: costruzione di una rete narrativa per l’implementazione dei processi inclusiviIl costrutto di inclusione nelle sue complesse sfaccettature mirate al superamento delle barriere all’apprendimento e alla partecipazione, ha guidato il presente lavoro di ricerca in ambito universitario alla luce della pedagogia e didattica speciale, sulla base dei parametri dell’Index for Inclusion, rilevando i livelli di progettazione integrata con il territorio. Il suo raggio di azione non si limita alla disabilità ma abbraccia tutti i bisogni educativi speciali, e l’isolamento, la marginalizzazione e/o le esclusioni che ne derivano. Rispetto al sistema universitario è rilevante interrogarsi sul processo di inclusione, in questo caso sulla base dell’approccio narrativo, preso atto che il modello organizzativo e le modalità di accesso e formative possono essere causa di esclusione formativa e sociale.
Locally specific measures for employment aimed at regional development
Directory of Open Access Journals (Sweden)
Vladimir Cini
2013-12-01
Full Text Available The oldest and largest sub-region in the world functioning on the principle of economic union is the European Union. The creation of a single market has initiated the process of conditional adjustment of markets in the EU member states, which has a significant impact on the social welfare of its citizens. It is necessary to tackle this issue by joint efforts within the European Union. As globalization processes push for economic integration and development of competitive advantage, the regions will have to make some challenging adjustments. The development tends to concentrate in highly competitive regions, while regions in the periphery lag behind. However, this pertains not only to the economic lag, but also to a potential negative political situation. Locally specific active employment policy measures are a continuation of the effort to make these measures more flexible. They refer to the Joint Assessment of Employment Policy Priorities and the IPA Human Resources Development Operational Programme - a regional policy instrument of the European Union. Both documents highlight the issue of disproportional development of regions, which requires special local measures and active labour market policy programmes. To reduce regional differences in development, it is necessary to invest more resources in the regions that lag behind. In this particular case, this means the counties in Croatia with high unemployment rates, a large number of registered unemployed persons and low employment rate. Consequently, this paper explains the importance of the adoption of locally specific measures for employment, which unfortunately did not take hold in the Republic of Croatia, and highlights the need for further decentralization of public services, with the aim of balancing regional development
Ultimate Educational Aims, Overridingness, and Personal Well-Being
Haji, Ishtiyaque; Cuypers, Stefaan E.
2011-01-01
Discussion regarding education's aims, especially its ultimate aims, is a key topic in the philosophy of education. These aims or values play a pivotal role in regulating and structuring moral and other types of normative education. We outline two plausible strategies to identify and justify education's ultimate aims. The first associates these…
Mepham, B.; Kaiser, M.; Thorstensen, E.; Tomkins, S.; Millar, K.
2006-01-01
The ethical matrix is a conceptual tool designed to help decision-makers (as individuals or working in groups) reach sound judgements or decisions about the ethical acceptability and/or optimal regulatory controls for existing or prospective technologies in the field of food and agriculture.
Mitjana, Margarida
2018-01-01
This book contains the notes of the lectures delivered at an Advanced Course on Combinatorial Matrix Theory held at Centre de Recerca Matemàtica (CRM) in Barcelona. These notes correspond to five series of lectures. The first series is dedicated to the study of several matrix classes defined combinatorially, and was delivered by Richard A. Brualdi. The second one, given by Pauline van den Driessche, is concerned with the study of spectral properties of matrices with a given sign pattern. Dragan Stevanović delivered the third one, devoted to describing the spectral radius of a graph as a tool to provide bounds of parameters related with properties of a graph. The fourth lecture was delivered by Stephen Kirkland and is dedicated to the applications of the Group Inverse of the Laplacian matrix. The last one, given by Ángeles Carmona, focuses on boundary value problems on finite networks with special in-depth on the M-matrix inverse problem.
Visualizing Matrix Multiplication
Daugulis, Peteris; Sondore, Anita
2018-01-01
Efficient visualizations of computational algorithms are important tools for students, educators, and researchers. In this article, we point out an innovative visualization technique for matrix multiplication. This method differs from the standard, formal approach by using block matrices to make computations more visual. We find this method a…
DEFF Research Database (Denmark)
Jørnø, Rasmus Leth Vergmann; Gynther, Karsten; Christensen, Ove
2014-01-01
useful information, we question whether the axis of time and space comprising the matrix pertains to relevant defining properties of the tools, technology or learning environments to which they are applied. Subsequently we offer an example of an Adobe Connect e-learning session as an illustration...
Spin chains and Gustafson's integrals
International Nuclear Information System (INIS)
Derkachov, S.E; Manashov, A.N.; Regensburg Univ.
2016-12-01
The Gustafson's integrals are the multidimensional generalization of the classical Mellin-Barnes integrals. We show that some of these integrals arise from relations between matrix elements in the Sklyanin's representation of Separated Variables in the spin chain models. We also present several new integrals.
Interpolation of rational matrix functions
Ball, Joseph A; Rodman, Leiba
1990-01-01
This book aims to present the theory of interpolation for rational matrix functions as a recently matured independent mathematical subject with its own problems, methods and applications. The authors decided to start working on this book during the regional CBMS conference in Lincoln, Nebraska organized by F. Gilfeather and D. Larson. The principal lecturer, J. William Helton, presented ten lectures on operator and systems theory and the interplay between them. The conference was very stimulating and helped us to decide that the time was ripe for a book on interpolation for matrix valued functions (both rational and non-rational). When the work started and the first partial draft of the book was ready it became clear that the topic is vast and that the rational case by itself with its applications is already enough material for an interesting book. In the process of writing the book, methods for the rational case were developed and refined. As a result we are now able to present the rational case as an indepe...
Directory of Open Access Journals (Sweden)
Ricardo Salazar-Díaz
2015-06-01
Traditional farming in Talamanca comes from the continuous and balanced relationship between humans and their natural environment; however, there is evidence of deterioration in this relationship. As a result of this initiative, this proposal intends to be a model to be replicated in neighboring communities and so contribute to sustainable human development in the region of Talamanca.
Phosphate-methylated DNA aimed at HIV-1 RNA loops and integrated DNA inhibits viral infectivity
Buck, H. M.; Koole, L. H.; van Genderen, M. H.; Smit, L.; Geelen, J. L.; Jurriaans, S.; Goudsmit, J.
1990-01-01
Phosphate-methylated DNA hybridizes strongly and specifically to natural DNA and RNA. Hybridization to single-stranded and double-stranded DNA leads to site-selective blocking of replication and transcription. Phosphate-methylated DNA was used to interrupt the life cycle of the human
Advanced Integrated Multi-sensor Surveillance (AIMS). Mission, Function, Task Analysis
2007-06-01
flaps, elevators and rudder control surfaces are based on conventional mechanical systems, using dual hydraulic boosters. Trim tabs are provided for... dumping the solid waste overboard it is difficult to determine its source. When an oil slick has been detected, the crew attempts to discover the...NAVCOM advises helicopter of on-scene weather, elevation, flight conditions and salient terrain features which may impact hoisting requirements
Advanced Integrated Multi-Sensor Surveillance (AIMS): Mission, Function, Task Analysis
2007-06-01
hydraulic boosters. Trim tabs are provided for the ailerons, elevators, and rudder surfaces. The wing flap is a high lift flowler type, and the flap...crew is able to observe and record a vessel dumping the solid waste overboard it is difficult to determine its source. When an oil slick has been...features which may impact hoisting requirements, as well as closest hospital facilities with helicopter access (North Battleford, SK). NAVCOM also
The Teacher Is a Learner: Dewey on Aims in Education
Harðarson, Atli
2018-01-01
In Chapter VIII of "Democracy and Education", Dewey objects to all three of the following propositions: (1) education serves predefined aims; (2) Education serves aims that are external to the process of education; and (3) Education serves aims that are imposed by authority. From the vantage point of policy-makers and authors of…
The Biblical Matrix of Economics
Directory of Open Access Journals (Sweden)
Grigore PIROŞCĂ
2012-05-01
Full Text Available The rationale of this paper is a prime pattern of history of economic thought in the previous ages of classic ancient times of Greek and Roman civilizations using a methodological matrix able to capture the mainstream ideas from social, political and religious events within the pages of Bible. The economic perspective of these events follows the evolution of the seeds of economic thinking within the Fertile Crescent, focused on the Biblical patriarchic heroes’ actions, but also on the empires which their civilization interacted to. The paper aims to discover the path followed by the economic doctrines from the Bible in order to find a match with economic actuality of present days.
Qian, Weixian; Zhou, Xiaojun; Lu, Yingcheng; Xu, Jiang
2015-09-15
Both the Jones and Mueller matrices encounter difficulties when physically modeling mixed materials or rough surfaces due to the complexity of light-matter interactions. To address these issues, we derived a matrix called the paths correlation matrix (PCM), which is a probabilistic mixture of Jones matrices of every light propagation path. Because PCM is related to actual light propagation paths, it is well suited for physical modeling. Experiments were performed, and the reflection PCM of a mixture of polypropylene and graphite was measured. The PCM of the mixed sample was accurately decomposed into pure polypropylene's single reflection, pure graphite's single reflection, and depolarization caused by multiple reflections, which is consistent with the theoretical derivation. Reflection parameters of rough surface can be calculated from PCM decomposition, and the results fit well with the theoretical calculations provided by the Fresnel equations. These theoretical and experimental analyses verify that PCM is an efficient way to physically model light-matter interactions.
International Nuclear Information System (INIS)
Sasakawa, T.; Okuno, H.; Ishikawa, S.; Sawada, T.
1982-01-01
The off-shell t matrix is expressed as a sum of one nonseparable and one separable terms so that it is useful for applications to more-than-two body problems. All poles are involved in this one separable term. Both the nonseparable and the separable terms of the kernel G 0 t are regular at the origin. The nonseparable term of this kernel vanishes at large distances, while the separable term behaves asymptotically as the spherical Hankel function. These properties make our expression free from defects inherent in the Jost or the K-matrix expressions, and many applications are anticipated. As the application, a compact expression of the many-level formula is presented. Also the application is suggested to the breakup threebody problem based on the Faddeev equation. It is demonstrated that the breakup amplitude is expressed in a simple and physically interesting form and we can calculate it in coordinate space
International Nuclear Information System (INIS)
Raju Viswanathan, R.
1991-09-01
We study examples of one dimensional matrix models whose potentials possess an energy spectrum that can be explicitly determined. This allows for an exact solution in the continuum limit. Specifically, step-like potentials and the Morse potential are considered. The step-like potentials show no scaling behaviour and the Morse potential (which corresponds to a γ = -1 model) has the interesting feature that there are no quantum corrections to the scaling behaviour in the continuum limit. (author). 5 refs
Wilkinson, Michael; Grant, John
2018-03-01
We consider a stochastic process in which independent identically distributed random matrices are multiplied and where the Lyapunov exponent of the product is positive. We continue multiplying the random matrices as long as the norm, ɛ, of the product is less than unity. If the norm is greater than unity we reset the matrix to a multiple of the identity and then continue the multiplication. We address the problem of determining the probability density function of the norm, \
Dijkgraaf, R; Verlinde, Herman L
1997-01-01
Via compactification on a circle, the matrix model of M-theory proposed by Banks et al suggests a concrete identification between the large N limit of two-dimensional N=8 supersymmetric Yang-Mills theory and type IIA string theory. In this paper we collect evidence that supports this identification. We explicitly identify the perturbative string states and their interactions, and describe the appearance of D-particle and D-membrane states.
Matrix groups for undergraduates
Tapp, Kristopher
2016-01-01
Matrix groups touch an enormous spectrum of the mathematical arena. This textbook brings them into the undergraduate curriculum. It makes an excellent one-semester course for students familiar with linear and abstract algebra and prepares them for a graduate course on Lie groups. Matrix Groups for Undergraduates is concrete and example-driven, with geometric motivation and rigorous proofs. The story begins and ends with the rotations of a globe. In between, the author combines rigor and intuition to describe the basic objects of Lie theory: Lie algebras, matrix exponentiation, Lie brackets, maximal tori, homogeneous spaces, and roots. This second edition includes two new chapters that allow for an easier transition to the general theory of Lie groups. From reviews of the First Edition: This book could be used as an excellent textbook for a one semester course at university and it will prepare students for a graduate course on Lie groups, Lie algebras, etc. … The book combines an intuitive style of writing w...
Extracellular matrix structure.
Theocharis, Achilleas D; Skandalis, Spyros S; Gialeli, Chrysostomi; Karamanos, Nikos K
2016-02-01
Extracellular matrix (ECM) is a non-cellular three-dimensional macromolecular network composed of collagens, proteoglycans/glycosaminoglycans, elastin, fibronectin, laminins, and several other glycoproteins. Matrix components bind each other as well as cell adhesion receptors forming a complex network into which cells reside in all tissues and organs. Cell surface receptors transduce signals into cells from ECM, which regulate diverse cellular functions, such as survival, growth, migration, and differentiation, and are vital for maintaining normal homeostasis. ECM is a highly dynamic structural network that continuously undergoes remodeling mediated by several matrix-degrading enzymes during normal and pathological conditions. Deregulation of ECM composition and structure is associated with the development and progression of several pathologic conditions. This article emphasizes in the complex ECM structure as to provide a better understanding of its dynamic structural and functional multipotency. Where relevant, the implication of the various families of ECM macromolecules in health and disease is also presented. Copyright © 2015 Elsevier B.V. All rights reserved.
CMS Proposal for the Engineering Data Management System (EDMS) Pilot Project with Matrix & Report
Kuipers, Jos
1997-01-01
The CMS Working Group for Engineering and Integration ( WOGEI) has been involved in the Engineering Data Management System ( EDMS) Task Force. This Task Force has started in 1995 with definition and selection procedure for an EDMS. The aim is to find out whether an EDMS is useful for CERN and the LHC experiments and which product is most suited. The CMS-WOGEI has proposed and carried out a pilot project with Matrix, the EDMS selected by the EDMS task force. In this technical note the pilot project is described and the experience gained with this is summarised.
Modulation and control of matrix converter for aerospace application
Kobravi, Keyhan
In the context of modern aircraft systems, a major challenge is power conversion to supply the aircraft's electrical instruments. These instruments are energized through a fixed-frequency internal power grid. In an aircraft, the available sources of energy are a set of variable-speed generators which provide variable-frequency ac voltages. Therefore, to energize the internal power grid of an aircraft, the variable-frequency ac voltages should be converted to a fixed-frequency ac voltage. As a result, an ac to ac power conversion is required within an aircraft's power system. This thesis develops a Matrix Converter to energize the aircraft's internal power grid. The Matrix Converter provides a direct ac to ac power conversion. A major challenge of designing Matrix Converters for aerospace applications is to minimize the volume and weight of the converter. These parameters are minimized by increasing the switching frequency of the converter. To design a Matrix Converter operating at a high switching frequency, this thesis (i) develops a scheme to integrate fast semiconductor switches within the current available Matrix Converter topologies, i.e., MOSFET-based Matrix Converter, and (ii) develops a new modulation strategy for the Matrix Converter. This Matrix Converter and the new modulation strategy enables the operation of the converter at a switching-frequency of 40kHz. To provide a reliable source of energy, this thesis also develops a new methodology for robust control of Matrix Converter. To verify the performance of the proposed MOSFET-based Matrix Converter, modulation strategy, and control design methodology, various simulation and experimental results are presented. The experimental results are obtained under operating condition present in an aircraft. The experimental results verify the proposed Matrix Converter provides a reliable power conversion in an aircraft under extreme operating conditions. The results prove the superiority of the proposed Matrix
Standard Errors for Matrix Correlations.
Ogasawara, Haruhiko
1999-01-01
Derives the asymptotic standard errors and intercorrelations for several matrix correlations assuming multivariate normality for manifest variables and derives the asymptotic standard errors of the matrix correlations for two factor-loading matrices. (SLD)
Reconstituted AIM2 inflammasome in cell-free system.
Kaneko, Naoe; Ito, Yuki; Iwasaki, Tomoyuki; Takeda, Hiroyuki; Sawasaki, Tatsuya; Migita, Kiyoshi; Agematsu, Kazunaga; Kawakami, Atsushi; Morikawa, Shinnosuke; Mokuda, Sho; Kurata, Mie; Masumoto, Junya
2015-11-01
Absent in melanoma 2 (AIM2) is an intracellular pattern-recognition receptor, which is a member of the PYHIN protein family, consisting of a PYD domain and an IFN-inducible nuclear localization (HIN) domain. AIM2 is reported to oligomerize with adaptor protein ASC upon sensing bacterial and viral cytosolic DNA in order to form the AIM2 inflammasome, which activates caspase-1 leading to IL-1β secretion. Dysregulation of AIM2 inflammasome is supposed to result in autoinflammatory and autoimmune diseases. Thus, the development of new targeted drugs against AIM2 inflammasome would be important for the treatment of these diseases. However, since AIM2 inflammasome is an intracellular receptor, enforced internalization of both ligands and candidate molecules is necessary for the screening of AIM2-inflammasome-targeted molecules. We developed a reconstituted AIM2 inflammasome in a cell-free system with amplified luminescent proximity homogeneous assay (Alpha). Strong Alpha signal was detected upon incubation with poly-deoxyadenylic-deoxythymidylic acid, poly(dA:dT), whereas no Alpha signal was detected upon incubation with muramyl dipeptide, one of the NLR ligands of Nod2 ligand. The interaction between AIM2 and ASC was disrupted by an anti-human ASC monoclonal antibody, CRID3, a class of diarylsulfonylurea-containing compounds, and glycyrrhizin, a substance found in liquorice root. Thus, the reconstituted AIM2 inflammasome in a cell-free system is useful for screening AIM2-inflammasome-targeted therapeutic molecules. Copyright © 2015 Elsevier B.V. All rights reserved.
Analysis of different alternatives for a reactor aimed to produce Co60. Neutronic part
International Nuclear Information System (INIS)
Relloso, J.M.
1990-01-01
Different alternatives are presented for a reactor aimed to produce radioisotopes with a low enrichment fuel element geometrically equal to those of low enrichment. Different alternatives are presented which essentially differ in the core's configuration, fuel management and 'meat' fuel material: U3O8, U3Si or U3Si2 in aluminium matrix. Fluxes at different irradiation positions and power full peak factors are described for each case. The main aspects to be taken into account for cobalt irradiation and the method to be followed to measure the reactor as a function of a required production are presented. (Author) [es
The finite temperature density matrix and two-point correlations in the antiferromagnetic XXZ chain
Göhmann, Frank; Hasenclever, Nils P.; Seel, Alexander
2005-10-01
We derive finite temperature versions of integral formulae for the two-point correlation functions in the antiferromagnetic XXZ chain. The derivation is based on the summation of density matrix elements characterizing a finite chain segment of length m. On this occasion we also supply a proof of the basic integral formula for the density matrix presented in an earlier publication.
Deift, Percy
2009-01-01
This book features a unified derivation of the mathematical theory of the three classical types of invariant random matrix ensembles-orthogonal, unitary, and symplectic. The authors follow the approach of Tracy and Widom, but the exposition here contains a substantial amount of additional material, in particular, facts from functional analysis and the theory of Pfaffians. The main result in the book is a proof of universality for orthogonal and symplectic ensembles corresponding to generalized Gaussian type weights following the authors' prior work. New, quantitative error estimates are derive
Eisenman, Richard L
2005-01-01
This outstanding text and reference applies matrix ideas to vector methods, using physical ideas to illustrate and motivate mathematical concepts but employing a mathematical continuity of development rather than a physical approach. The author, who taught at the U.S. Air Force Academy, dispenses with the artificial barrier between vectors and matrices--and more generally, between pure and applied mathematics.Motivated examples introduce each idea, with interpretations of physical, algebraic, and geometric contexts, in addition to generalizations to theorems that reflect the essential structur
Directory of Open Access Journals (Sweden)
Abdelhakim Chillali
2017-05-01
Full Text Available In classical cryptography, the Hill cipher is a polygraphic substitution cipher based on linear algebra. In this work, we proposed a new problem applicable to the public key cryptography, based on the Matrices, called “Matrix discrete logarithm problem”, it uses certain elements formed by matrices whose coefficients are elements in a finite field. We have constructed an abelian group and, for the cryptographic part in this unreliable group, we then perform the computation corresponding to the algebraic equations, Returning the encrypted result to a receiver. Upon receipt of the result, the receiver can retrieve the sender’s clear message by performing the inverse calculation.
Matrix string partition function
Kostov, Ivan K; Kostov, Ivan K.; Vanhove, Pierre
1998-01-01
We evaluate quasiclassically the Ramond partition function of Euclidean D=10 U(N) super Yang-Mills theory reduced to a two-dimensional torus. The result can be interpreted in terms of free strings wrapping the space-time torus, as expected from the point of view of Matrix string theory. We demonstrate that, when extrapolated to the ultraviolet limit (small area of the torus), the quasiclassical expressions reproduce exactly the recently obtained expression for the partition of the completely reduced SYM theory, including the overall numerical factor. This is an evidence that our quasiclassical calculation might be exact.
The Aims of Education and the Leap of Freedom
Yun, SunInn
2014-01-01
This paper considers the place of freedom in discussions of the aims of education. Bearing in mind remarks of R.S. Peters to the affect that the singling out of aims can "fall into the hands of rationalistically minded curriculum planners", it begins by considering the views of Roland Reichenbach regarding Bildung and his account of this…
The Logic of Deferral: Educational Aims and Intellectual Disability
Taylor, Ashley
2018-01-01
The educational aims described by educational philosophers rarely embrace the full range of differences in intellectual ability, adaptive behavior, or communication that children exhibit. Because envisioned educational aims have significant consequences for how educational practices, pedagogy, and curricula are conceptualized, the failure to…
Teaching Design Education for Cultural, Pedagogical, and Economic Aims
Vande Zande, Robin
2010-01-01
The aims of educating for economic, cultural, and pedagogical purposes have existed since the early inception of art education. Looking at how and why these aims evolved in the early era of art and design education has potential for better understanding how and why design should be incorporated into the art education curricula today. This article…
Database on Aims and Visions in the COINCO Corridor
DEFF Research Database (Denmark)
2005-01-01
This database contains aims and visions regarding overall regional development as well as more specific aims and visions related to transport and infrastructure in the Corridor Oslo-Göteborg-Copenhagen-Berlin. The sources used for this database are the most essential planning documents from Denmark...
The compatibility between extension aims of staff and their ...
African Journals Online (AJOL)
This pilot investigation was done to investigate the compatibility between extension aims of extension staff and those of their employer. It shows that only 50 percent of respondents have an acceptable understanding of the official aims (vision), and that none of the components of the official vision has sufficient compatibility ...
Matrix algebra for linear models
Gruber, Marvin H J
2013-01-01
Matrix methods have evolved from a tool for expressing statistical problems to an indispensable part of the development, understanding, and use of various types of complex statistical analyses. This evolution has made matrix methods a vital part of statistical education. Traditionally, matrix methods are taught in courses on everything from regression analysis to stochastic processes, thus creating a fractured view of the topic. Matrix Algebra for Linear Models offers readers a unique, unified view of matrix analysis theory (where and when necessary), methods, and their applications. Written f
Chern-Simons matrix models and unoriented strings
International Nuclear Information System (INIS)
Halmagyi, Nick; Yasnov, Vadim
2004-01-01
For matrix models with measure on the Lie algebra of SO/Sp, the sub-leading free energy is given by F 1 (S) ±{1/4}({δF 0 (S)}/{δS}). Motivated by the fact that this relationship does not hold for Chern-Simons theory on S 3 , we calculate the sub-leading free energy in the matrix model for this theory, which is a Gaussian matrix model with Haar measure on the group SO/Sp. We derive a quantum loop equation for this matrix model and then find that F 1 is an integral of the leading order resolvent over the spectral curve. We explicitly calculate this integral for quadratic potential and find agreement with previous studies of SO/Sp Chern-Simons theory. (author)
Massively parallel sparse matrix function calculations with NTPoly
Dawson, William; Nakajima, Takahito
2018-04-01
We present NTPoly, a massively parallel library for computing the functions of sparse, symmetric matrices. The theory of matrix functions is a well developed framework with a wide range of applications including differential equations, graph theory, and electronic structure calculations. One particularly important application area is diagonalization free methods in quantum chemistry. When the input and output of the matrix function are sparse, methods based on polynomial expansions can be used to compute matrix functions in linear time. We present a library based on these methods that can compute a variety of matrix functions. Distributed memory parallelization is based on a communication avoiding sparse matrix multiplication algorithm. OpenMP task parallellization is utilized to implement hybrid parallelization. We describe NTPoly's interface and show how it can be integrated with programs written in many different programming languages. We demonstrate the merits of NTPoly by performing large scale calculations on the K computer.
Benchmark matrix and guide: Part II.
1991-01-01
In the last issue of the Journal of Quality Assurance (September/October 1991, Volume 13, Number 5, pp. 14-19), the benchmark matrix developed by Headquarters Air Force Logistics Command was published. Five horizontal levels on the matrix delineate progress in TQM: business as usual, initiation, implementation, expansion, and integration. The six vertical categories that are critical to the success of TQM are leadership, structure, training, recognition, process improvement, and customer focus. In this issue, "Benchmark Matrix and Guide: Part II" will show specifically how to apply the categories of leadership, structure, and training to the benchmark matrix progress levels. At the intersection of each category and level, specific behavior objectives are listed with supporting behaviors and guidelines. Some categories will have objectives that are relatively easy to accomplish, allowing quick progress from one level to the next. Other categories will take considerable time and effort to complete. In the next issue, Part III of this series will focus on recognition, process improvement, and customer focus.
Modeling the formation of cell-matrix adhesions on a single 3D matrix fiber.
Escribano, J; Sánchez, M T; García-Aznar, J M
2015-11-07
Cell-matrix adhesions are crucial in different biological processes like tissue morphogenesis, cell motility, and extracellular matrix remodeling. These interactions that link cell cytoskeleton and matrix fibers are built through protein clutches, generally known as adhesion complexes. The adhesion formation process has been deeply studied in two-dimensional (2D) cases; however, the knowledge is limited for three-dimensional (3D) cases. In this work, we simulate different local extracellular matrix properties in order to unravel the fundamental mechanisms that regulate the formation of cell-matrix adhesions in 3D. We aim to study the mechanical interaction of these biological structures through a three dimensional discrete approach, reproducing the transmission pattern force between the cytoskeleton and a single extracellular matrix fiber. This numerical model provides a discrete analysis of the proteins involved including spatial distribution, interaction between them, and study of the different phenomena, such as protein clutches unbinding or protein unfolding. Copyright © 2015 Elsevier Ltd. All rights reserved.
Implementation of an Anesthesia Information Management System (AIMS).
Douglas, James R; Ritter, Melody J
2011-01-01
During the administration of anesthesia, the anesthesia provider has historically created a paper record, charted manually, that included extensive patient care-related data (vital signs, other parameters, etc) and commentaries. DocuSys, a proprietary anesthesia information management system (AIMS), creates an electronic version of the anesthesia record and provides additional information. It electronically captures data from clinical monitors and other sources, including scheduling applications and laboratory computers. The AIMS facilitates chart entries such as drug doses and case narratives. Benefits of an AIMS include improved legibility of the anesthesia record and greater efficiency in documentation efforts. Use of the AIMS assists the practitioner with decision support logic, such as the timing of antibiotic administration and the inclusion of legally required documentation. Upon case completion, the AIMS data are immediately available to other information systems, such as billing and medical records. Data can be made available from a single case or, more important, from thousands of cases to analyze variables such as efficiency of services, adherence to best practices, patient outcomes, and clinical research. The AIMS was deployed at the main campus of the Ochsner Health System on March 26, 2009. In this article, we discuss the issues involved in the AIMS implementation process: the successes, surprises, and continued challenges.
Characterization of supercapacitors matrix
Energy Technology Data Exchange (ETDEWEB)
Sakka, Monzer Al, E-mail: Monzer.Al.Sakka@vub.ac.b [Vrije Universiteit Brussel, pleinlaan 2, B-1050 Brussels (Belgium); FEMTO-ST Institute, ENISYS Department, FCLAB, UFC-UTBM, bat.F, 90010 Belfort (France); Gualous, Hamid, E-mail: Hamid.Gualous@unicaen.f [Laboratoire LUSAC, Universite de Caen Basse Normandie, Rue Louis Aragon - BP 78, 50130 Cherbourg-Octeville (France); Van Mierlo, Joeri [Vrije Universiteit Brussel, pleinlaan 2, B-1050 Brussels (Belgium)
2010-10-30
This paper treats supercapacitors matrix characterization. In order to cut off transient power peaks and to compensate for the intrinsic limitations in embedded sources, the use of supercapacitors as a storage system is quite suitable, because of their appropriate electrical characteristics (huge capacitance, small series resistance, high specific energy, high specific power), direct storage (energy ready for use), and easy control by power electronic conversion. This use requires supercapacitors modules where several cells connected in serial and/or in parallel, thus a bypass system to balance the charging or the discharging of supercapacitors is required. In the matrix of supercapacitors, six elements of three parallel BCAP0350 supercapacitors in serial connections have been considered. This topology permits to reduce the number of the bypass circuits and it can work in degraded mode. Actually, it allows the system to have more reliability by providing power continually to the load even when there are one or more cells failed. Simulation and experimental results are presented and discussed.
Characterization of supercapacitors matrix
International Nuclear Information System (INIS)
Sakka, Monzer Al; Gualous, Hamid; Van Mierlo, Joeri
2010-01-01
This paper treats supercapacitors matrix characterization. In order to cut off transient power peaks and to compensate for the intrinsic limitations in embedded sources, the use of supercapacitors as a storage system is quite suitable, because of their appropriate electrical characteristics (huge capacitance, small series resistance, high specific energy, high specific power), direct storage (energy ready for use), and easy control by power electronic conversion. This use requires supercapacitors modules where several cells connected in serial and/or in parallel, thus a bypass system to balance the charging or the discharging of supercapacitors is required. In the matrix of supercapacitors, six elements of three parallel BCAP0350 supercapacitors in serial connections have been considered. This topology permits to reduce the number of the bypass circuits and it can work in degraded mode. Actually, it allows the system to have more reliability by providing power continually to the load even when there are one or more cells failed. Simulation and experimental results are presented and discussed.
A review of intervention studies aimed at household energy conservation
Abrahamse, W; Steg, L; Vlek, C; Rothengatter, T; Rothengatter, J.A.
This article reviews and evaluates the effectiveness of interventions aiming to encourage households to reduce energy consumption. Thirty-eight studies performed within the field of (applied) social and environmental psychology are reviewed, and categorized as involving either antecedent strategies
Positive psychological interventions aimed at enhancing psychological ownership
van Zyl, Llewellyn; van der Vaart, Leoni; Stemmet, Lehan; Olckers, Chantal; van Zyl, Llewellyn; van der Vaart, Leoni
2017-01-01
Interventions aimed at the enhancement of positive organisational behaviours, within organisational contexts, are imperative for creating and sustaining a high-performance culture, where individual and organisational strengths are optimized and top-talent retained. Psychological ownership, one form
AIM analysis, synthetic, kinetic and mechanistic investigations of the ...
Indian Academy of Sciences (India)
analysis (NPA), atoms in molecules (AIM) methods and CHelpG keyword. ... obtained from studies of the effect of solvent, structure of reactions (different alkyl groups within the dialkyl ...... compounds) have provided useful evidence for steps 1.
Americans aim to overhaul science teaching by 2061
1990-01-01
Project 2061 is a long-term initiative by the AAAS to reform classroom science. Deputy director Walter Gillespie claims that the aim is for schools to teach less content but teach it better (1/2 page).
Rosemann, T.J.; Korner, T.; Wensing, M.J.P.; Schneider, A.; Szecsenyi, J.
2005-01-01
OBJECTIVES: The aim of the study was to examine the validity of a translated and culturally adapted version of the Arthritis Impact Measurement Scales 2, Short Form (AIMS2-SF) in patients suffering from osteoarthritis (OA) in primary care. METHODS: A structured procedure was used for the translation
Depolarization artifacts in dual rotating-compensator Mueller matrix ellipsometry
International Nuclear Information System (INIS)
Li, Weiqi; Zhang, Chuanwei; Jiang, Hao; Chen, Xiuguo; Liu, Shiyuan
2016-01-01
Noticeable depolarization effects are observed in the measurement of the air using an in-house developed dual rotating-compensator Mueller matrix ellipsometer. We demonstrate that these depolarization effects are essentially artifacts and mainly induced when the compensator with wavelength-dependent optical properties is integrated with the finite bandwidth detector. We define a general formula to represent the actual Mueller matrix of the compensator by taking into account the depolarization artifacts. After incorporating this formula into the system model, a correction method is further proposed, and consequently, improved accuracy can be achieved in the Mueller matrix measurement. (paper)
Ethics and aims in psychotherapy: a contribution from Kant.
Callender, J S
1998-08-01
Psychotherapy is an activity which takes many forms and which has many aims. The present paper argues that it can be viewed as a form of moral suasion. Kant's concepts of free will and ethics are described and these are then applied to the processes and outcome of psychotherapy. It is argued that his ideas, by linking rationality, free will and ethics into a single philosophical system, offer a valuable theoretical framework for thinking about aims and ethical issues in psychotherapy.
[Content analysis of food adverts aimed at children].
Ponce-Blandón, José Antonio; Pabón-Carrasco, Manuel; Lomas-Campos, María de Las Mercedes
To determine the contents and persuasive techniques used in processed food adverts aimed at children in Andalusia, comparing them with those aimed at adults. Study based on advert content analysis with two phases: a descriptive design phase and an analytical observational design phase. A sample of adverts from 60hours of broadcasting from the two most watched television channels in Andalusia. A total of 416 food and non-alcoholic beverage adverts were obtained, for 91 different products. Approximately 42.9% (n=39) was aimed at children and 53.8% (n=49) were products classified as "unhealthy". Unhealthy foods were more common in adverts for children (p <0.001). Significant differences were found between the ads aimed at adults and those aimed at children. Emotional and irrational persuasive resources such as fantasy (p <0.001), cartoons (p <0.001) or offering gifts with the purchase of the product (p=0.003) were observed more frequently in adverts for children. Food advertising aimed at children in Andalusia is mainly based on offering products with a low nutritional value and using persuasive resources based on fantasy or gifts. The message is focused on the incentive and not the food. More effective measures than the current self-regulatory systems must be put in place to counter these distorted adverts. Copyright © 2017 SESPAS. Publicado por Elsevier España, S.L.U. All rights reserved.
Host Proteins Determine MRSA Biofilm Structure and Integrity
DEFF Research Database (Denmark)
Dreier, Cindy; Nielsen, Astrid; Jørgensen, Nis Pedersen
Human extracellular matrix (hECM) proteins aids the initial attachment and initiation of an infection, by specific binding to bacterial cell surface proteins. However, the importance of hECM proteins in structure, integrity and antibiotic resilience of a biofilm is unknown. This study aims...... to determine how specific hECM proteins affect S. aureus USA300 JE2 biofilms. Biofilms were grown in the presence of synovial fluid from rheumatoid arteritis patients to mimic in vivo conditions, where bacteria incorporate hECM proteins into the biofilm matrix. Difference in biofilm structure, with and without...... addition of hECM to growth media, was visualized by confocal laser scanning microscopy. Two enzymatic degradation experiments were used to study biofilm matrix composition and importance of hECM proteins: enzymatic removal of specific hECM proteins from growth media, before biofilm formation, and enzymatic...
Ceramic matrix and resin matrix composites - A comparison
Hurwitz, Frances I.
1987-01-01
The underlying theory of continuous fiber reinforcement of ceramic matrix and resin matrix composites, their fabrication, microstructure, physical and mechanical properties are contrasted. The growing use of organometallic polymers as precursors to ceramic matrices is discussed as a means of providing low temperature processing capability without the fiber degradation encountered with more conventional ceramic processing techniques. Examples of ceramic matrix composites derived from particulate-filled, high char yield polymers and silsesquioxane precursors are provided.
Ceramic matrix and resin matrix composites: A comparison
Hurwitz, Frances I.
1987-01-01
The underlying theory of continuous fiber reinforcement of ceramic matrix and resin matrix composites, their fabrication, microstructure, physical and mechanical properties are contrasted. The growing use of organometallic polymers as precursors to ceramic matrices is discussed as a means of providing low temperature processing capability without the fiber degradation encountered with more conventional ceramic processing techniques. Examples of ceramic matrix composites derived from particulate-filled, high char yield polymers and silsesquioxane precursors are provided.
Correlation functions of two-matrix models
International Nuclear Information System (INIS)
Bonora, L.; Xiong, C.S.
1993-11-01
We show how to calculate correlation functions of two matrix models without any approximation technique (except for genus expansion). In particular we do not use any continuum limit technique. This allows us to find many solutions which are invisible to the latter technique. To reach our goal we make full use of the integrable hierarchies and their reductions which were shown in previous papers to naturally appear in multi-matrix models. The second ingredient we use, even though to a lesser extent, are the W-constraints. In fact an explicit solution of the relevant hierarchy, satisfying the W-constraints (string equation), underlies the explicit calculation of the correlation functions. The correlation functions we compute lend themselves to a possible interpretation in terms of topological field theories. (orig.)
Matrix factorizations, minimal models and Massey products
International Nuclear Information System (INIS)
Knapp, Johanna; Omer, Harun
2006-01-01
We present a method to compute the full non-linear deformations of matrix factorizations for ADE minimal models. This method is based on the calculation of higher products in the cohomology, called Massey products. The algorithm yields a polynomial ring whose vanishing relations encode the obstructions of the deformations of the D-branes characterized by these matrix factorizations. This coincides with the critical locus of the effective superpotential which can be computed by integrating these relations. Our results for the effective superpotential are in agreement with those obtained from solving the A-infinity relations. We point out a relation to the superpotentials of Kazama-Suzuki models. We will illustrate our findings by various examples, putting emphasis on the E 6 minimal model
Nanotechnology and nanomedicine: going small means aiming big.
Teli, Mahesh Kumar; Mutalik, Srinivas; Rajanikant, G K
2010-06-01
Nanotechnology is an emerging branch of science for designing tools and devices of size 1 to 100 nm with specific function at the cellular, atomic and molecular levels. The concept of employing nanotechnology in biomedical research and clinical practice is best known as nanomedicine. Nanomedicine is an upcoming field that could potentially make a major impact to human health. Nanomaterials are increasingly used in diagnostics, imaging and targeted drug delivery. Nanotechnology will assist the integration of diagnostics/imaging with therapeutics and facilitates the development of personalized medicine, i.e. prescription of specific medications best suited for an individual. This review provides an integrated overview of application of nanotechnology based molecular diagnostics and drug delivery in the development of nanomedicine and ultimately personalized medicine. Finally, we identify critical gaps in our knowledge of nanoparticle toxicity and how these gaps need to be evaluated to enable nanotechnology to transit safely from bench to bedside.
International Nuclear Information System (INIS)
Craps, Ben; Sethi, Savdeep; Verlinde, Erik
2005-01-01
The light-like linear dilaton background represents a particularly simple time-dependent 1/2 BPS solution of critical type-IIA superstring theory in ten dimensions. Its lift to M-theory, as well as its Einstein frame metric, are singular in the sense that the geometry is geodesically incomplete and the Riemann tensor diverges along a light-like subspace of codimension one. We study this background as a model for a big bang type singularity in string theory/M-theory. We construct the dual Matrix theory description in terms of a (1+1)-d supersymmetric Yang-Mills theory on a time-dependent world-sheet given by the Milne orbifold of (1+1)-d Minkowski space. Our model provides a framework in which the physics of the singularity appears to be under control
Energy Technology Data Exchange (ETDEWEB)
Craps, Ben [Instituut voor Theoretische Fysica, Universiteit van Amsterdam, Valckenierstraat 65, 1018 XE Amsterdam (Netherlands); Sethi, Savdeep [Enrico Fermi Institute, University of Chicago, Chicago, IL 60637 (United States); Verlinde, Erik [Instituut voor Theoretische Fysica, Universiteit van Amsterdam, Valckenierstraat 65, 1018 XE Amsterdam (Netherlands)
2005-10-15
The light-like linear dilaton background represents a particularly simple time-dependent 1/2 BPS solution of critical type-IIA superstring theory in ten dimensions. Its lift to M-theory, as well as its Einstein frame metric, are singular in the sense that the geometry is geodesically incomplete and the Riemann tensor diverges along a light-like subspace of codimension one. We study this background as a model for a big bang type singularity in string theory/M-theory. We construct the dual Matrix theory description in terms of a (1+1)-d supersymmetric Yang-Mills theory on a time-dependent world-sheet given by the Milne orbifold of (1+1)-d Minkowski space. Our model provides a framework in which the physics of the singularity appears to be under control.
Report on DOE labs takes aim at cleanup
International Nuclear Information System (INIS)
Anon.
1995-01-01
This article is a review of the Galvin report on the environmental restoration activities at DOE nuclear facilities. The report is highly critical of DOE efforts, calling for a management overhaul and partial privitization of some facilities. Urging that the facilities be more integrated into the environmental management program, the report asserts that the low quality of science and technology in field cleanup work is the most important reason for the limited pace of cleanup activities. Excessive administrative costs were also cited
Matrix metalloproteinases outside vertebrates.
Marino-Puertas, Laura; Goulas, Theodoros; Gomis-Rüth, F Xavier
2017-11-01
The matrix metalloproteinase (MMP) family belongs to the metzincin clan of zinc-dependent metallopeptidases. Due to their enormous implications in physiology and disease, MMPs have mainly been studied in vertebrates. They are engaged in extracellular protein processing and degradation, and present extensive paralogy, with 23 forms in humans. One characteristic of MMPs is a ~165-residue catalytic domain (CD), which has been structurally studied for 14 MMPs from human, mouse, rat, pig and the oral-microbiome bacterium Tannerella forsythia. These studies revealed close overall coincidence and characteristic structural features, which distinguish MMPs from other metzincins and give rise to a sequence pattern for their identification. Here, we reviewed the literature available on MMPs outside vertebrates and performed database searches for potential MMP CDs in invertebrates, plants, fungi, viruses, protists, archaea and bacteria. These and previous results revealed that MMPs are widely present in several copies in Eumetazoa and higher plants (Tracheophyta), but have just token presence in eukaryotic algae. A few dozen sequences were found in Ascomycota (within fungi) and in double-stranded DNA viruses infecting invertebrates (within viruses). In contrast, a few hundred sequences were found in archaea and >1000 in bacteria, with several copies for some species. Most of the archaeal and bacterial phyla containing potential MMPs are present in human oral and gut microbiomes. Overall, MMP-like sequences are present across all kingdoms of life, but their asymmetric distribution contradicts the vertical descent model from a eubacterial or archaeal ancestor. This article is part of a Special Issue entitled: Matrix Metalloproteinases edited by Rafael Fridman. Copyright © 2017 Elsevier B.V. All rights reserved.
Uncertainty in aiming movements and its association to hand function
Directory of Open Access Journals (Sweden)
Flávia Priscila de Paiva Silva
2015-09-01
Full Text Available AbstractThe purpose of this study was to analyze the influence of the uncertainty of target location on the planning and execution of aiming movements performed towards the ipsilateral and contralateral directions by the right and left upper limbs. In addition, the association between the performance of aiming movements and the performance of functional manual tasks was investigated. Two tasks were proposed: with prior knowledge of the movement direction (simple reaction time or not (choice reaction time. The grip strength and manual dexterity were measured. The choice option in response (i.e. uncertainty influenced planning of the aiming movements, but not its execution, while movements performed towards the contralateral direction were worse in execution as compared to the ipsilateral direction. Manual dexterity was significantly correlated with reaction times, while the performance during movement execution was significantly correlated with handgrip/pinch strength.
Neutral-beam aiming and calorimetry for MFTF-B
International Nuclear Information System (INIS)
Goldner, A.I.; Margolies, D.
1981-01-01
The vessel for the Tandem Mirror Fusion Test Facility (MFTF-B) will have up to eleven 0.5-s-duration neutral-beam injectors for the initial heating of the MFTF-B plasma. Knowing the exact alignment of the beams and their total power is critical to the performance of the experiment. Using prototype aiming and calorimetry systems on the High Voltage Test Stand (HVTS) at Lawrence Livermore National Laboratory (LLNL), we hope to prove our ability to obtain an aiming accuracy of +-1 cm at the plasma and a calorimetric accuracy of +-5% of the actual total beam energy
S3T working group. Report 1: group aims
International Nuclear Information System (INIS)
Pouey, M.
1983-04-01
The work group S3T which is aimed to designing and developing devices using unconventional holographic optics is presented. These devices find applications that are classified here in four items high resolution spectrometers, high definition imaging, high flux devices, metrology and interferometry. The problems to solve and the aims of the group in each of these cases are presented. Three synthesis of lectures are in this report. The main one concerns stigmatism conditions of concave holographic gratings used in normal incidence. This new process of focusing is very interesting for hot plasma diagnostics [fr
Phenomenology of the CKM matrix
International Nuclear Information System (INIS)
Nir, Y.
1989-01-01
The way in which an exact determination of the CKM matrix elements tests the standard Model is demonstrated by a two-generation example. The determination of matrix elements from meson semileptonic decays is explained, with an emphasis on the respective reliability of quark level and meson level calculations. The assumptions involved in the use of loop processes are described. Finally, the state of the art of the knowledge of the CKM matrix is presented. 19 refs., 2 figs
Matrix transformations and sequence spaces
International Nuclear Information System (INIS)
Nanda, S.
1983-06-01
In most cases the most general linear operator from one sequence space into another is actually given by an infinite matrix and therefore the theory of matrix transformations has always been of great interest in the study of sequence spaces. The study of general theory of matrix transformations was motivated by the special results in summability theory. This paper is a review article which gives almost all known results on matrix transformations. This also suggests a number of open problems for further study and will be very useful for research workers. (author)
Multivariate Matrix-Exponential Distributions
DEFF Research Database (Denmark)
Bladt, Mogens; Nielsen, Bo Friis
2010-01-01
be written as linear combinations of the elements in the exponential of a matrix. For this reason we shall refer to multivariate distributions with rational Laplace transform as multivariate matrix-exponential distributions (MVME). The marginal distributions of an MVME are univariate matrix......-exponential distributions. We prove a characterization that states that a distribution is an MVME distribution if and only if all non-negative, non-null linear combinations of the coordinates have a univariate matrix-exponential distribution. This theorem is analog to a well-known characterization theorem...
International Nuclear Information System (INIS)
Dorey, Nick; Tong, David; Turner, Carl
2016-01-01
We study a U(N) gauged matrix quantum mechanics which, in the large N limit, is closely related to the chiral WZW conformal field theory. This manifests itself in two ways. First, we construct the left-moving Kac-Moody algebra from matrix degrees of freedom. Secondly, we compute the partition function of the matrix model in terms of Schur and Kostka polynomials and show that, in the large N limit, it coincides with the partition function of the WZW model. This same matrix model was recently shown to describe non-Abelian quantum Hall states and the relationship to the WZW model can be understood in this framework.
Advanced Industrial Materials (AIM) Program annual progress report, FY 1997
Energy Technology Data Exchange (ETDEWEB)
NONE
1998-05-01
The Advanced Industrial Materials (AIM) Program is a part of the Office of Industrial Technologies (OIT), Energy Efficiency and Renewable Energy, US Department of Energy (DOE). The mission of AIM is to support development and commercialization of new or improved materials to improve energy efficiency, productivity, product quality, and reduced waste in the major process industries. OIT has embarked on a fundamentally new way of working with industries--the Industries of the Future (IOF) strategy--concentrating on the major process industries that consume about 90% of the energy and generate about 90% of the waste in the industrial sector. These are the aluminum, chemical, forest products, glass, metalcasting, and steel industries. OIT has encouraged and assisted these industries in developing visions of what they will be like 20 or 30 years into the future, defining the drivers, technology needs, and barriers to realization of their visions. These visions provide a framework for development of technology roadmaps and implementation plans, some of which have been completed. The AIM Program supports IOF by conducting research and development on materials to solve problems identified in the roadmaps. This is done by National Laboratory/industry/university teams with the facilities and expertise needed to develop new and improved materials. Each project in the AIM Program has active industrial participation and support.
Refractive aim and visual outcome after phacoemulsification: A 2 ...
African Journals Online (AJOL)
2016-03-24
Mar 24, 2016 ... was met, 21 eyes (14.3%) did not meet their refractive aim, 20 eyes (12.7%) were ... countries, where blindness is associated with considerable ... and better, the total range of refractive errors postoperatively ... required intraocular lenses (IOL), medical record efficiency, ..... problem that can be alleviated.
R. S. Peters' Normative Conception of Education and Educational Aims
Katz, Michael S.
2009-01-01
This article aims to highlight why R. S. Peters' conceptual analysis of "education" was such an important contribution to the normative field of philosophy of education. In the article, I do the following: 1) explicate Peters' conception of philosophy of education as a field of philosophy and explain his approach to the philosophical analysis of…
Anxiety and ironic effects in aiming at a far target
Bakker, F.C.; Binsch, O.
2011-01-01
In far aiming the negative intention not to miss may ironically increase the tendency to do precisely that. Although cognitive constraints enhance the occurrence of ironic effects in the perceptual-motor domain the role of anxiety in inducing such effects has rarely been investigated while anxiety
Advanced Industrial Materials (AIM) Program: Annual progress report FY 1995
Energy Technology Data Exchange (ETDEWEB)
NONE
1996-04-01
In many ways, the Advanced Industrial Materials (AIM) Program underwent a major transformation in Fiscal Year 1995 and these changes have continued to the present. When the Program was established in 1990 as the Advanced Industrial Concepts (AIC) Materials Program, the mission was to conduct applied research and development to bring materials and processing technologies from the knowledge derived from basic research to the maturity required for the end use sectors for commercialization. In 1995, the Office of Industrial Technologies (OIT) made radical changes in structure and procedures. All technology development was directed toward the seven ``Vision Industries`` that use about 80% of industrial energy and generated about 90% of industrial wastes. The mission of AIM has, therefore, changed to ``Support development and commercialization of new or improved materials to improve productivity, product quality, and energy efficiency in the major process industries.`` Though AIM remains essentially a National Laboratory Program, it is essential that each project have industrial partners, including suppliers to, and customers of, the seven industries. Now, well into FY 1996, the transition is nearly complete and the AIM Program remains reasonably healthy and productive, thanks to the superb investigators and Laboratory Program Managers. This Annual Report for FY 1995 contains the technical details of some very remarkable work by the best materials scientists and engineers in the world. Areas covered here are: advanced metals and composites; advanced ceramics and composites; polymers and biobased materials; and new materials and processes.
Ecological radiation monotoring in NPP region, aims and tasks
International Nuclear Information System (INIS)
Egorov, Yu.A.
1986-01-01
Aims and tasks of ecological radiation monitoring in the NPP region are discussed. The aims of monitoring are: to determine possible sequences of NPP radioactive release effects on ecosystems, taking place on the background of chemical and thermal pollution to develop standard of radiation effect on ecosystems; the aims includes also obtaining of information for forecasting and evaluating long-term radiation effects, establishment of factors characterizing the ecosystem state, establishment of a combined effect of radioactive wastes with chemical and thermal ones. Finally, the aim of monitoring consists in providing the natural object conservation in the NPP region under optimal operation conditions. Thus it is necessary to solve the following problems: to observe systematically release, transport and transformation, when transporting radioactive and chemical contaminants in terrestial and aquatic biocenoses, as well as injection and transport in them of waste heat; to observe systematically the natural physico-chemical, chemico-biological processes affecting the injection and transport of contaminants in ecosystem components; to observe systematically the natural and, probably, antropogenic processes; to carry out systematically observations of the ecosystem state in the NPP region and eco-systems-monitors
Student Aims Performance in a Predominately Hispanic District
Chebultz, Lance
2012-01-01
School districts in the United States have undergone large changes over the last decade to accommodate No Child Left Behind (NCLB). Arizona accommodated NCLB through Arizona's Instrument to Measure Standards (AIMS). Expectations were established for all students, varying by group of students based on grade, special education status, free/reduced…
Pursuing the Triple Aim: The First 7 Years.
Whittington, John W; Nolan, Kevin; Lewis, Ninon; Torres, Trissa
2015-06-01
POLICY POINTS: In 2008, researchers at the Institute for Healthcare Improvement (IHI) proposed the Triple Aim, strategic organizing principles for health care organizations and geographic communities that seek, simultaneously, to improve the individual experience of care and the health of populations and to reduce the per capita costs of care for populations. In 2010, the Triple Aim became part of the US national strategy for tackling health care issues, especially in the implementation of the Patient Protection and Affordable Care Act (ACA) of 2010. Since that time, IHI and others have worked together to determine how the implementation of the Triple Aim has progressed. Drawing on our 7 years of experience, we describe 3 major principles that guided the organizations and communities working on this endeavor: creating the right foundation for population management, managing services at scale for the population, and establishing a learning system to drive and sustain the work over time. In 2008, researchers at the Institute for Healthcare Improvement (IHI) described the Triple Aim as simultaneously "improving the individual experience of care; improving the health of populations; and reducing the per capita costs of care for populations." IHI and its close colleagues had determined that both individual and societal changes were needed. In 2007, IHI began recruiting organizations from around the world to participate in a collaborative to implement what became known as the Triple Aim. The 141 participating organizations included health care systems, hospitals, health care insurance companies, and others closely tied to health care. In addition, key groups outside the health care system were represented, such as public health agencies, social services groups, and community coalitions. This collaborative provided a structure for observational research. By noting the contrasts between the contexts and structures of those sites in the collaborative that progressed and
Universal Authenticated Item Monitoring System (AIMS) second generation equipment
International Nuclear Information System (INIS)
Schoeneman, J.L.; Baumann, M.J.; Fox, L.J.; Jenkins, C.D.; Perlinsk, A.W.
1992-01-01
Sandia National Laboratories (SNL) is in the final stages of developing a Universal Authenticated Item Monitoring System (AIMS). When completed, AIMS will provide applicable agencies in the US government, and those in the International arena, with a secure and convenient method of monitoring the physical status of selected items. The benefit derived from this development activity will be the commercial availability of an item monitoring system with the capability for ''quick set-up'' monitoring, as well as long-term unattended monitoring. The AIMS includes a variety of sensors, a robust and authenticated radio frequency (RF) communication link, a Receiver Processing Unit (RPU), and an inspector-friendly personal computer (PC) interface for collecting, sorting, viewing and archiving pertinent event histories. The system will provide the capability to monitor selected items in a real-time mode, a remotely interrogated mode, and a stand-alone, unattended data collection mode. The sensor suite under development includes advanced motion sensors, interior volumetric intrusion sensors, Re-usable, In-situ Verifiable Authenticated (RIVA) fiber-optic seal sensors, generic utility sensors (to accommodate contact closure inputs), and radiation and environmental sensors. A new generation authentication algorithm recently has been developed that provides a high degree of system security 121. The AIMS has potential safeguards applications in the areas of arms control and treaty verification military asset control, International Atomic Energy Agency (IAEA) and Euratom safeguards verification activities, as well as domestic nuclear safeguard activities. Commercial applications could include high-value inventory control and security systems. This paper describes the second-generation AIMS along with its recently expanded sensor suite and enhanced data collection capabilities
Incorporating Level-2 PSA Feature of CONPAS into AIMS-PSA Software
International Nuclear Information System (INIS)
Han, Sang Hoon; Lim, Hogon; Ahn, Kwang Il
2014-01-01
CONPAS (CONtainment Performance Analysis System) utilizes a methodology to treat containment phenomena in detail like APET but in simple way. In mid 2000's, KAERI has developed very fast cut set generator FTREX and PC's OS (Operating system) has changed into Windows 95. Thus, KAERI has developed new Level-1 PSA software, called AIMS-PSA (Advanced Information Management System for PSA) to replace KIRAP. Recently, KAERI has been developing an integrated PSA platform, called OCEANS (On-line Consolidator and Evaluator of All mode risk for Nuclear System), for the risk assessment of all power modes and all hazards. CONPAS for Level-2 PSA was developed in 1990's using the Visual Basic 6.0 compiler which is not supported any more. It needs to be updated for the integrated PSA software framework. This paper describes a study to incorporate the features of CONPAS into AIMS-PSA. The basic idea is to follow the approach of CONPAS, but in the integrated way. Various approaches for Level-2 PSA have been used since WASH-1400. APET approach of NUREG-1150 study would be most comprehensive and complex methodology for containment event tree analysis. CONPAS is the Level-2 PSA software to utilize an approach to treat containment phenomena in detail like APET but in simple way. But, new Level-2 PSA software is required to develop more integrated PSA framework. A modified approach of CONPAS is developed and incorporated in AIMS-PSA software that can handle Level-1 and Level-2 PSA in the integrated way (from the viewpoint of event tree and fault tree). AIMS-PSA combines whole Level-2 PSA model to produce a One Top fault tree and to generate cut sets in the same way as Level-1 PSA. Quantification results of Level-2 PSA such as frequency for each STC can be calculated from the minimal cut sets
Poly(3-hexylthiophene): TIPS-pentacene blends aiming transistor applications
Energy Technology Data Exchange (ETDEWEB)
Silva Ozório, Maiza da, E-mail: ozoriounesp@gmail.com; Nogueira, Gabriel Leonardo; Morais, Rogério Miranda; Silva Martin, Cibely da; Constantino, Carlos José Leopoldo; Alves, Neri
2016-06-01
Poly(3-hexylthiophene):6,13-bis(triisopropylsilylethynyl)-pentacene (P3HT:TP) blends with a ratio of 1:1 (wt/wt) were deposited via spin coating on anodized oxide (Al{sub 2}O{sub 3}). A phase separation of the compounds was observed, resulting in the formation of crystalline aggregates of TP molecules that segregate vertically on the surface. The form of segregation depends on the oxide surface treatment used. Spectroscopy analysis shows a higher molecular order of P3HT in the blend than for neat film and that TP molecules are also distributed in the polymeric matrix. Regarding the OFET characteristics, charge carrier mobilities of 1.2 × 10{sup −3} cm{sup 2} V{sup −1} s{sup −1} and 2.0 × 10{sup −3} cm{sup 2} V{sup −1} s{sup −1} were obtained from devices for untreated and (hexamethyldisilazane) HMDS-treated Al{sub 2}O{sub 3} gate dielectric, respectively. These results confirm that P3HT:TP blends have good potential as an active layer in organic field effect transistors (OFETs). - Highlights: • Phase separation occurs in the P3HT:TP blend. • The P3HT:TP blends form aggregates that segregate vertically to the surface. • The molecular order of the P3HT is higher for the blend than for the neat film. • Treatment of surface with HMDS influence in the formation of the aggregate • The P3HT:TP blends have great viability of using for application in transistors.
International Nuclear Information System (INIS)
Perdicakis, Michel
2012-01-01
Document available in extended abstract form only. In many countries, it is planned that the long life highly radioactive nuclear spent fuel will be stored in deep argillaceous rocks. The sites selected for this purpose are anoxic and satisfy several recommendations as mechanical stability, low permeability and low redox potential. Pyrite (FeS 2 ), iron(II) carbonate, iron(II) bearing clays and organic matter that are present in very small amounts (about 1% w:w) in soils play a major role in their reactivity and are considered today as responsible for the low redox potential values of these sites. In this communication, we describe an electrochemical technique derived from 'Salt matrix voltammetry' and allowing the almost in-situ voltammetric characterization of air-sensitive samples of soils after the only addition of the minimum humidity required for electrolytic conduction. Figure 1 shows the principle of the developed technique. It consists in the entrapment of the clay sample between a graphite working electrode and a silver counter/quasi-reference electrode. The sample was previously humidified by passing a water saturated inert gas through the electrochemical cell. The technique leads to well-defined voltammetric responses of the electro-active components of the clays. Figure 2 shows a typical voltammogram relative to a Callovo-Oxfordian argillite sample from Bure, the French place planned for the underground nuclear waste disposal. During the direct scan, one can clearly distinguish the anodic voltammetric signals for the oxidation of the iron (II) species associated with the clay and the oxidation of pyrite. The reverse scan displays a small cathodic signal for the reduction of iron (III) associated with the clay that demonstrates that the majority of the previously oxidized iron (II) species were transformed into iron (III) oxides reducible at lower potentials. When a second voltammetric cycle is performed, one can notice that the signal for iron (II
Automated Instrumentation, Monitoring and Visualization of PVM Programs Using AIMS
Mehra, Pankaj; VanVoorst, Brian; Yan, Jerry; Lum, Henry, Jr. (Technical Monitor)
1994-01-01
We present views and analysis of the execution of several PVM (Parallel Virtual Machine) codes for Computational Fluid Dynamics on a networks of Sparcstations, including: (1) NAS Parallel Benchmarks CG and MG; (2) a multi-partitioning algorithm for NAS Parallel Benchmark SP; and (3) an overset grid flowsolver. These views and analysis were obtained using our Automated Instrumentation and Monitoring System (AIMS) version 3.0, a toolkit for debugging the performance of PVM programs. We will describe the architecture, operation and application of AIMS. The AIMS toolkit contains: (1) Xinstrument, which can automatically instrument various computational and communication constructs in message-passing parallel programs; (2) Monitor, a library of runtime trace-collection routines; (3) VK (Visual Kernel), an execution-animation tool with source-code clickback; and (4) Tally, a tool for statistical analysis of execution profiles. Currently, Xinstrument can handle C and Fortran 77 programs using PVM 3.2.x; Monitor has been implemented and tested on Sun 4 systems running SunOS 4.1.2; and VK uses XIIR5 and Motif 1.2. Data and views obtained using AIMS clearly illustrate several characteristic features of executing parallel programs on networked workstations: (1) the impact of long message latencies; (2) the impact of multiprogramming overheads and associated load imbalance; (3) cache and virtual-memory effects; and (4) significant skews between workstation clocks. Interestingly, AIMS can compensate for constant skew (zero drift) by calibrating the skew between a parent and its spawned children. In addition, AIMS' skew-compensation algorithm can adjust timestamps in a way that eliminates physically impossible communications (e.g., messages going backwards in time). Our current efforts are directed toward creating new views to explain the observed performance of PVM programs. Some of the features planned for the near future include: (1) ConfigView, showing the physical topology
Learning object for teacher training aimed to develop communication skills
Directory of Open Access Journals (Sweden)
Norma Esmeralda RODRÍGUEZ RAMÍREZ
2014-06-01
Full Text Available This article presents the results and reflections obtained across a research aimed to analyze the quality criteria of an opened learning object oriented to develop communication skills in order to be able to report and validate it according to its content, pedagogic structure, technological structure, graphical and textual language and usability to teacher training, in order to base it theoretically, pedagogically and technologically. The research question was: Which are the quality criteria that a learning object aimed to develop communication skills must cover? Under a quantitative approach, there were electronic questionnaires applied to: 34 Technological University teachers, eight experts about of communicative competence, teaching, technology and graphic design. The results indicated that some of the quality criteria of learning object are: the effective managing of the learning content, the balanced composition of his pedagogic structure, the technological structure efficiency and the proper managing of graphical and textual language.
Research methodology the aims, practices and ethics of science
Pruzan, Peter
2016-01-01
This book is an in-depth guide to effective scientific research. Ranging from the philosophical to the practical, it explains at the outset what science can – and can’t – achieve, and discusses its relationship to mathematics and laws. The author then pays extensive attention to the scientific method, including experimental design, verification, uncertainty and statistics. A major aim of the book is to help young scientists reflect upon the deeper aims of their work and make the best use of their talents in contributing to progress. To this end, it also includes sections on planning research, on presenting one’s findings in writing, as well as on ethics and the responsibilities of scientists. .
Determination of aims military-technical policy of Ukraine
Directory of Open Access Journals (Sweden)
O. F. Salnikova
2014-06-01
Full Text Available In the article the aims of military-technical policy are considered. Determination of aims (tasks of military-technical policy, its maintenance, requirements to it and directions of its further development it must come true by the analysis of different factors of external and internal environment. Among such factors: geopolitical and military-political position of Ukraine and its military doctrine; realized and operating programs of development (reformation of the soldiery forming and them technical rigging; terms of future military operations and progress of their maintenance, forms, methods and characteristic signs of battle actions trend; substantive provisions of art of war; conceptions, theories and doctrines of battle application of the soldiery forming of the different states; resources dedicated by the state on development of military-technical sphere and others like that. The fundamental chart of sequence of forming of public military-technical policy is presented in the article.
Use of Probiotic Microorganisms for Bio-Protective Aims
Directory of Open Access Journals (Sweden)
Filiz YANGILAR
2015-03-01
Full Text Available It was known that some diseases can be treated as the result of the use of antibiotics in certain periods and at certain dosages while inactivating and deteriorating normal microorganisms performing useful activities in human metabolism (in especially intestinal flora. It was occured that after the use of antibiotics, some defects can be seen resulting from antibiotics (such as allergy, diarrhea, gas formation etc. With this aim, nutraceutics and functional food have gained importance over the last years and consumers began to be interested in probiotics, natural antioxidants, dietary fibres, products with low calorie and cholesterol contents, especially the products containing probioticbacteria. Bacteriocins produced by probiotic bacteria can play important roles as food protective and safeguarding since they can compete with unwanted or pathogen microorganisms survive in the media and colonize in intestines. In this review, is aimed to emphasis bioprotective compounds, advantages and disadvantages of biopreservation method and the importance of the mechanisms of probiotic microorganisms.
Ceramic matrix composite article and process of fabricating a ceramic matrix composite article
Cairo, Ronald Robert; DiMascio, Paul Stephen; Parolini, Jason Robert
2016-01-12
A ceramic matrix composite article and a process of fabricating a ceramic matrix composite are disclosed. The ceramic matrix composite article includes a matrix distribution pattern formed by a manifold and ceramic matrix composite plies laid up on the matrix distribution pattern, includes the manifold, or a combination thereof. The manifold includes one or more matrix distribution channels operably connected to a delivery interface, the delivery interface configured for providing matrix material to one or more of the ceramic matrix composite plies. The process includes providing the manifold, forming the matrix distribution pattern by transporting the matrix material through the manifold, and contacting the ceramic matrix composite plies with the matrix material.
Energy Technology Data Exchange (ETDEWEB)
1966-06-01
Development now being carried out by ASEA is aimed at increasing the normal operating voltage for a mercury arc valve to 250 kV dc. The maximum direct voltage per valve group, with one valve in each arm of the bridge, is 125 kV for equipment already in operation in New Zealand, Japan, and Konti Scan. Valves for 130 kV and 133 kV operation are under construction for the Vancouver and the Pacific Intertie 1 links.
Action Information Management System (AIMS): a User's View
Wiskerchen, M.
1984-01-01
The initial approach used in establishing a user-defined information system to fulfill the needs of users at NASA Headquarters was unsuccessful in bringing this pilot endeaveor to full project status. The persistence of several users and the full involvement of the Ames Research Center were the ingredients needed to make the AIMS project a success. The lesson learned from this effort is that NASA should always work from its organizational strengths as a Headquarters-Center partnership.
Retrospective study of thyroid cancer treatment: aims and data
International Nuclear Information System (INIS)
Vosmikova, K.; Hermanska, J.; Jirsa, L.; Karny, M.; Samal, M.
1998-01-01
Although opinions preferring individual administration of activity in the treatment of thyroid cancer with 131 I predominate, sufficient quantitative arguments in favor of this approach are unavailable as yet. Therefore, a retrospective study involving statistical processing was proposed with the aim to evaluate the relations between available data of the patients and success of treatment. Ideally, recommendations regarding activity to be administered in dependence on the biophysical status of the patient should emerge from the study
Advanced Industrial Materials (AIM) program. Annual progress report. FY 1996
Energy Technology Data Exchange (ETDEWEB)
NONE
1997-04-01
The Advanced Industrial Materials (AIM) Program underwent a major transformation in Fiscal Year 1995 and these changes have continued to the present. When the Program was established in 1990 as the Advanced Industrial Concepts (AIC) Materials Program, the mission was to conduct applied research and development to bring materials and processing technologies from the knowledge derived from basic research to the maturity required for the end use sectors for commercialization. In 1995, the Office of Industrial Technologies (OIT) made radical changes in structure and procedures. All technology development was directed toward the seven `Vision Industries` that use about 80% of industrial energy and generated about 90% of industrial wastes. These are: aluminium; chemical; forest products; glass; metal casting; refineries; and steel. OIT is working with these industries, through appropriate organizations, to develop Visions of the desired condition of each industry some 20 or 25 years in the future and then to prepare Road Maps and Implementation Plans to enable them to reach their goals. The mission of AIM has, therefore, changed to `Support development and commercialization of new or improved materials to improve productivity, product quality, and energy efficiency in the major process industries.` Though AIM remains essentially a National Laboratory Program, it is necessary that each project have industrial partners, including suppliers to, and customers of, the seven industries. Now, well into FY 1996, the transition is nearly complete and the AIM Program remains healthy and productive, thanks to the superb investigators and Laboratory Program Managers. Separate abstracts have been indexed into the energy database for articles from this report.
Aims and Formats of performance measurement at Danish Universities
DEFF Research Database (Denmark)
Raffnsøe-Møller, Morten
2011-01-01
Abstract This article traces the aims and formats of performance measurement of Danish Universities as they originate from the Ministry of Finance’s plan for governance of the public sector. The article further show that the fierce conflicts between central administration and the universities over...... and intelligent regimes – is used to propose a way out of the current governance impasse at the universities....
Ocean Science Video Challenge Aims to Improve Science Communication
Showstack, Randy
2013-10-01
Given today's enormous management and protection challenges related to the world's oceans, a new competition calls on ocean scientists to effectively communicate their research in videos that last up to 3 minutes. The Ocean 180 Video Challenge, named for the number of seconds in 3 minutes, aims to improve ocean science communication while providing high school and middle school teachers and students with new and interesting educational materials about current science topics.
Dissociated effects of distractors on saccades and manual aiming.
McIntosh, Robert D; Buonocore, Antimo
2012-08-01
The remote distractor effect (RDE) is a robust phenomenon whereby target-directed saccades are delayed by the appearance of a distractor. This effect persists even when the target location is perfectly predictable. The RDE has been studied extensively in the oculomotor domain but it is unknown whether it generalises to other spatially oriented responses. In three experiments, we tested whether the RDE generalises to manual aiming. Experiment 1 required participants to move their hand or eyes to predictable targets presented alone or accompanied by a distractor in the opposite hemifield. The RDE was observed for the eyes but not for the hand. Experiment 2 replicated this dissociation in a more naturalistic task in which eye movements were not constrained during manual aiming. Experiment 3 confirmed the lack of manual RDE across a wider range of distractor delays (0, 50, 100, and 150 ms). Our data imply that the RDE is specific to the oculomotor system, at least for non-foveal distractors. We suggest that the oculomotor RDE reflects competitive interactions between target and distractor representations in the superior colliculus, which are not necessarily shared by manual aiming.
Systems Engineering and Integration for Advanced Life Support System and HST
Kamarani, Ali K.
2005-01-01
Systems engineering (SE) discipline has revolutionized the way engineers and managers think about solving issues related to design of complex systems: With continued development of state-of-the-art technologies, systems are becoming more complex and therefore, a systematic approach is essential to control and manage their integrated design and development. This complexity is driven from integration issues. In this case, subsystems must interact with one another in order to achieve integration objectives, and also achieve the overall system's required performance. Systems engineering process addresses these issues at multiple levels. It is a technology and management process dedicated to controlling all aspects of system life cycle to assure integration at all levels. The Advanced Integration Matrix (AIM) project serves as the systems engineering and integration function for the Human Support Technology (HST) program. AIM provides means for integrated test facilities and personnel for performance trade studies, analyses, integrated models, test results, and validated requirements of the integration of HST. The goal of AIM is to address systems-level integration issues for exploration missions. It will use an incremental systems integration approach to yield technologies, baselines for further development, and possible breakthrough concepts in the areas of technological and organizational interfaces, total information flow, system wide controls, technical synergism, mission operations protocols and procedures, and human-machine interfaces.
Jairam, Dharmananda; Kiewra, Kenneth A.; Kauffman, Douglas F.; Zhao, Ruomeng
2012-01-01
This study investigated how best to study a matrix. Fifty-three participants studied a matrix topically (1 column at a time), categorically (1 row at a time), or in a unified way (all at once). Results revealed that categorical and unified study produced higher: (a) performance on relationship and fact tests, (b) study material satisfaction, and…
Aiming toward perfection with POBSYS, a new software system
International Nuclear Information System (INIS)
Osudar, J.; Parks, J.E.; Levitz, N.M.
1985-01-01
An integrated general-purpose software system, POBSYS, has been developed that provides the foundation and tools for building a highly interactive system for carrying out detailed operating procedures and performing conventional process control, data acquisition, and data management functions. Features of the present system, which may be of particular interest to the problem of the man-machine interface include: (a) a multi-level safety system for fail-safe operation; (b) hierarchical operational control; (c) documented responsibility; (d) equipment status tracking; and (e) quality assurance checks on operations. The system runs on commercially available microprocessors and is presently in use in the destructive analysis of irradiated fuel rods from the Light Water Breeder Reactor
Modeling cometary photopolarimetric characteristics with Sh-matrix method
Kolokolova, L.; Petrov, D.
2017-12-01
Cometary dust is dominated by particles of complex shape and structure, which are often considered as fractal aggregates. Rigorous modeling of light scattering by such particles, even using parallelized codes and NASA supercomputer resources, is very computer time and memory consuming. We are presenting a new approach to modeling cometary dust that is based on the Sh-matrix technique (e.g., Petrov et al., JQSRT, 112, 2012). This method is based on the T-matrix technique (e.g., Mishchenko et al., JQSRT, 55, 1996) and was developed after it had been found that the shape-dependent factors could be separated from the size- and refractive-index-dependent factors and presented as a shape matrix, or Sh-matrix. Size and refractive index dependences are incorporated through analytical operations on the Sh-matrix to produce the elements of T-matrix. Sh-matrix method keeps all advantages of the T-matrix method, including analytical averaging over particle orientation. Moreover, the surface integrals describing the Sh-matrix elements themselves can be solvable analytically for particles of any shape. This makes Sh-matrix approach an effective technique to simulate light scattering by particles of complex shape and surface structure. In this paper, we present cometary dust as an ensemble of Gaussian random particles. The shape of these particles is described by a log-normal distribution of their radius length and direction (Muinonen, EMP, 72, 1996). Changing one of the parameters of this distribution, the correlation angle, from 0 to 90 deg., we can model a variety of particles from spheres to particles of a random complex shape. We survey the angular and spectral dependencies of intensity and polarization resulted from light scattering by such particles, studying how they depend on the particle shape, size, and composition (including porous particles to simulate aggregates) to find the best fit to the cometary observations.
Agrawal, Shantanu; Conway, Patrick H
2014-09-01
The Triple Aim of better health, better care, and lower costs has become a fundamental framework for understanding the need for broad health care reform and describing health care value. While the framework is not specific to any clinical setting, this article focuses on the alignment between the framework and Emergency Department (ED) care. The paper explores where emergency care is naturally aligned with each Aim, as well as current barriers which must be addressed to meet the full vision of the Triple Aim. We propose a vision of EDs serving as a nexus for care coordination optimally consistent with the Triple Aim and the requirements for such a role. These requirements include: (1) substantial integration in coordinated care models; (2) development of reliable and actionable data on ED quality, population health, and cost outcomes; (3) specific initiatives to control and optimize ED utilization; and (4) payment models which preserve surge and disaster response capacity. Published by Elsevier Inc.
Path Integrals in Quantum Mechanics
International Nuclear Information System (INIS)
Louko, J
2005-01-01
Jean Zinn-Justin's textbook Path Integrals in Quantum Mechanics aims to familiarize the reader with the path integral as a calculational tool in quantum mechanics and field theory. The emphasis is on quantum statistical mechanics, starting with the partition function Tr exp(-β H) and proceeding through the diffusion equation to barrier penetration problems and their semiclassical limit. The 'real time' path integral is defined via analytic continuation and used for the path-integral representation of the nonrelativistic S-matrix and its perturbative expansion. Holomorphic and Grassmannian path integrals are introduced and applied to nonrelativistic quantum field theory. There is also a brief discussion of path integrals in phase space. The introduction includes a brief historical review of path integrals, supported by a bibliography with some 40 entries. As emphasized in the introduction, mathematical rigour is not a central issue in the book. This allows the text to present the calculational techniques in a very readable manner: much of the text consists of worked-out examples, such as the quartic anharmonic oscillator in the barrier penetration chapter. At the end of each chapter there are exercises, some of which are of elementary coursework type, but the majority are more in the style of extended examples. Most of the exercises indeed include the solution or a sketch thereof. The book assumes minimal previous knowledge of quantum mechanics, and some basic quantum mechanical notation is collected in an appendix. The material has a large overlap with selected chapters in the author's thousand-page textbook Quantum Field Theory and Critical Phenomena (2002 Oxford: Clarendon). The stand-alone scope of the present work has, however, allowed a more focussed organization of this material, especially in the chapters on, respectively, holomorphic and Grassmannian path integrals. In my view the book accomplishes its aim admirably and is eminently usable as a textbook
Bulk metallic glass matrix composites
International Nuclear Information System (INIS)
Choi-Yim, H.; Johnson, W.L.
1997-01-01
Composites with a bulk metallic glass matrix were synthesized and characterized. This was made possible by the recent development of bulk metallic glasses that exhibit high resistance to crystallization in the undercooled liquid state. In this letter, experimental methods for processing metallic glass composites are introduced. Three different bulk metallic glass forming alloys were used as the matrix materials. Both ceramics and metals were introduced as reinforcement into the metallic glass. The metallic glass matrix remained amorphous after adding up to a 30 vol% fraction of particles or short wires. X-ray diffraction patterns of the composites show only peaks from the second phase particles superimposed on the broad diffuse maxima from the amorphous phase. Optical micrographs reveal uniformly distributed particles in the matrix. The glass transition of the amorphous matrix and the crystallization behavior of the composites were studied by calorimetric methods. copyright 1997 American Institute of Physics
Quantum mechanics in matrix form
Ludyk, Günter
2018-01-01
This book gives an introduction to quantum mechanics with the matrix method. Heisenberg's matrix mechanics is described in detail. The fundamental equations are derived by algebraic methods using matrix calculus. Only a brief description of Schrödinger's wave mechanics is given (in most books exclusively treated), to show their equivalence to Heisenberg's matrix method. In the first part the historical development of Quantum theory by Planck, Bohr and Sommerfeld is sketched, followed by the ideas and methods of Heisenberg, Born and Jordan. Then Pauli's spin and exclusion principles are treated. Pauli's exclusion principle leads to the structure of atoms. Finally, Dirac´s relativistic quantum mechanics is shortly presented. Matrices and matrix equations are today easy to handle when implementing numerical algorithms using standard software as MAPLE and Mathematica.
Notes on Mayer expansions and matrix models
International Nuclear Information System (INIS)
Bourgine, Jean-Emile
2014-01-01
Mayer cluster expansion is an important tool in statistical physics to evaluate grand canonical partition functions. It has recently been applied to the Nekrasov instanton partition function of N=2 4d gauge theories. The associated canonical model involves coupled integrations that take the form of a generalized matrix model. It can be studied with the standard techniques of matrix models, in particular collective field theory and loop equations. In the first part of these notes, we explain how the results of collective field theory can be derived from the cluster expansion. The equalities between free energies at first orders is explained by the discrete Laplace transform relating canonical and grand canonical models. In a second part, we study the canonical loop equations and associate them with similar relations on the grand canonical side. It leads to relate the multi-point densities, fundamental objects of the matrix model, to the generating functions of multi-rooted clusters. Finally, a method is proposed to derive loop equations directly on the grand canonical model
Acid activation of natural clays aiming their application in adsorption
International Nuclear Information System (INIS)
Silva, M.M. da; Sousa, A.K.F. de; Lima, W.S.; Vasconcelos, P.N.M. de; Rodrigues, M. G.F.
2012-01-01
Clays of smectite type have wide application in industrial, mainly due to their adsorption properties. However, it is necessary to subject them to chemical treatments to optimize their potential. This study aimed to analyze the effects of acid activation on the clay Brasgel fresh. In the acid activation was used concentrated hydrochloric acid at different concentrations (3M, 4.5 M and 6 M) at a temperature of 70 ° C for 30 minutes. The samples fresh and activated technique were characterized by X-ray Diffraction (XRD). The results show that the properties of clay after activation are improved, it could be used as adsorbents in the treatment of wastewater. (author)
A Core Design Approach Aimed at Sustainability and Intrinsic Safety
International Nuclear Information System (INIS)
Grasso, Giacomo
2013-01-01
The comprehensive approach adopted for the core design of all LFRs investigated within the LEADER project, proved to effectively drive the design to the fulfillment of the aimed sustainability performances, and the respect of the design constraints for the robust implementation of the inherent safety principle: • the ELFR core is able to operate adiabatically, with a very narrow reactivity swing along a 2.5 y cycle; • wide margins are provided for protecting the fuel and the structures even in case of unprotected transients, allowing for very long grace times
No norm needed: on the aim of belief
DEFF Research Database (Denmark)
Steglich-Petersen, Asbjørn
2006-01-01
Does transparency in doxastic deliberation entail a constitutive norm of correctness governing belief, as Shah and Velleman argue? No, because this presupposes an implausibly strong relation between normative judgements and motivation from such judgements, ignores our interest in truth, and cannot...... explain why we pay different attention to how much justification we have for our beliefs in different contexts. An alternative account of transparency is available: transparency can be explained by the aim one necessarily adopts in deliberating about whether to believe that p. To show this, I reconsider...... the role of the concept of belief in doxastic deliberation, and I defuse 'the teleologian's dilemma'....
NASA tells physicists to aim for the stars
MacIlwain, C
1999-01-01
Dan Goldin, administrator at NASA, suggested that the next generation of instruments for high-energy physics research should be built in space. This did not go down well at Fermilab where a case is being made for a new ground-based accelerator. Goldin's aim though was simply to tell the scientific community that NASA is prepared to spend big money on physics in space. NASA also wants to work more closely with the DOE and the NSF to support space-based experiments (1 page).
Matrix fluid chemistry experiment. Final report June 1998 - March 2003
International Nuclear Information System (INIS)
Smellie, John A.T.; Waber, H. Niklaus; Frape, Shaun K.
2003-06-01
The Matrix Fluid Chemistry Experiment set out to determine the composition and evolution of matrix pore fluids/waters in low permeable rock located at repository depths in the Aespoe Hard Rock Laboratory (HRL). Matrix pore fluids/waters can be highly saline in composition and, if accessible, may influence the near-field groundwater chemistry of a repository system. Characterising pore fluids/waters involved in-situ borehole sampling and analysis integrated with laboratory studies and experiments on rock matrix drill core material. Relating the rate of in-situ pore water accumulation during sampling to the measured rock porosity indicated a hydraulic conductivity of 10 -14 -10 -13 m/s for the rock matrix. This was in accordance with earlier estimated predictions. The sampled matrix pore water, brackish in type, mostly represents older palaeo- groundwater mixtures preserved in the rock matrix and dating back to at least the last glaciation. A component of matrix pore 'fluid' is also present. One borehole section suggests a younger groundwater component which has accessed the rock matrix during the experiment. There is little evidence that the salinity of the matrix pore waters has been influenced significantly by fluid inclusion populations hosted by quartz. Crush/leach, cation exchange, pore water diffusion and pore water displacement laboratory experiments were carried out to compare extracted/calculated matrix pore fluids/waters with in-situ sampling. Of these the pore water diffusion experiments appear to be the most promising approach and a recommended site characterisation protocol has been formulated. The main conclusions from the Matrix Fluid Chemistry Experiment are: Groundwater movement within the bedrock hosting the experimental site has been enhanced by increased hydraulic gradients generated by the presence of the tunnel, and to a much lesser extent by the borehole itself. Over experimental timescales ∼4 years) solute transport through the rock matrix
Matrix fluid chemistry experiment. Final report June 1998 - March 2003
Energy Technology Data Exchange (ETDEWEB)
Smellie, John A.T. [Conterra AB, Luleaa (Sweden); Waber, H. Niklaus [Univ. of Bern (Switzerland). Inst. of Geology; Frape, Shaun K. [Univ. of Waterloo (Canada). Dept. of Earth Sciences
2003-06-01
The Matrix Fluid Chemistry Experiment set out to determine the composition and evolution of matrix pore fluids/waters in low permeable rock located at repository depths in the Aespoe Hard Rock Laboratory (HRL). Matrix pore fluids/waters can be highly saline in composition and, if accessible, may influence the near-field groundwater chemistry of a repository system. Characterising pore fluids/waters involved in-situ borehole sampling and analysis integrated with laboratory studies and experiments on rock matrix drill core material. Relating the rate of in-situ pore water accumulation during sampling to the measured rock porosity indicated a hydraulic conductivity of 10{sup -14}-10{sup -13} m/s for the rock matrix. This was in accordance with earlier estimated predictions. The sampled matrix pore water, brackish in type, mostly represents older palaeo- groundwater mixtures preserved in the rock matrix and dating back to at least the last glaciation. A component of matrix pore 'fluid' is also present. One borehole section suggests a younger groundwater component which has accessed the rock matrix during the experiment. There is little evidence that the salinity of the matrix pore waters has been influenced significantly by fluid inclusion populations hosted by quartz. Crush/leach, cation exchange, pore water diffusion and pore water displacement laboratory experiments were carried out to compare extracted/calculated matrix pore fluids/waters with in-situ sampling. Of these the pore water diffusion experiments appear to be the most promising approach and a recommended site characterisation protocol has been formulated. The main conclusions from the Matrix Fluid Chemistry Experiment are: Groundwater movement within the bedrock hosting the experimental site has been enhanced by increased hydraulic gradients generated by the presence of the tunnel, and to a much lesser extent by the borehole itself. Over experimental timescales {approx}4 years) solute transport
Directory of Open Access Journals (Sweden)
Lioara-Bianca BUBOIU
2015-04-01
Full Text Available Accepting and valuing people with disabilities is a key aspect of social policies promoted worldwide. The implementation of these policies aim normalize the lives of people with disabilities through full integration in the society to which they belong. Removing discrimination and social barriers equates to a maturing of the society, maturing translated by accepting diversity that surrounds us. Each person must be appreciated at its true value regardless of its condition of normality or deviation from it. Valuing individuals can be achieved only through a full acceptance in society, by assigning statuses and fulfilling social roles. School integration of children with special educational needs in mainstream education is a challenge and involves many aspects to be successful. It is the premise of social integration, the basis for future socio-professional insertion. Integrated education is the first step towards a world of equal opportunities, a world without discrimination.
Silva, Simone dos Santos
In the last decades, tissue engineering has emerged as a potential therapeutical tool aimed at developing substitutes that are able to restore proper function of the damaged organs/tissues. Nature-inspired routes involving natural origin polymer-based systems represent an attractive alternative to produce novel materials by mimicking the tissue environment required for tissue regeneration. Moreover, further modifications of these systems allow the adjustment of their properties in accordance with the requirements for successful biomedical applications. The main goal of the present thesis is to develop and modify natural origin polymer-based systems using simple methodologies such as sol-gel, surface modification by means of plasma treatment and blending of chitosan with proteins (soy protein isolate and silk fibroin). A sol-gel method was used to improve the bulk properties of chitosan by the incorporation of an inorganic component at the sub-nanometric level. Chitosan/siloxane hybrid materials were synthesised, where essentially urea bridges covalently bond the chitosan to the polysiloxane network. These bifunctional materials exhibit interesting photoluminescence features and a bioactive behaviour. In most situations in the biomedical field, the surface of a biomaterial is in direct contact with living tissues. Therefore, the surface characteristics play a fundamental role on the implant biocompatibility. In this thesis, nitrogen and argon plasma treatment was applied on chitosan membranes in order to improve their surface properties. The applied modifications promoted differences on surface chemistry, wettability and roughness, which reflected in a significant improvement of fibroblast adhesion and proliferation onto chitosan membranes. Besides the surface modification, blending of chitosan with proteins such as soy protein isolate and silk fibroin was also used to modify the bulk properties of chitosan. In situ cross-linking with glutaraldehyde solutions was
Linking aims, paradigm and method in nursing research.
Houghton, Catherine; Hunter, Andrew; Meskell, Pauline
2012-01-01
To explore the use of paradigms as ontological and philosophical guides for conducting PhD research. A paradigm can help to bridge the aims of a study and the methods to achieve them. However, choosing a paradigm can be challenging for doctoral researchers: there can be ambiguity about which paradigm is suitable for a particular research question and there is a lack of guidance on how to shape the research process for a chosen paradigm. The authors discuss three paradigms used in PhD nursing research: post-positivism, interpretivism and pragmatism. They compare each paradigm in relation to its ontology, epistemology and methodology, and present three examples of PhD nursing research studies to illustrate how research can be conducted using these paradigms in the context of the research aims and methods. The commonalities and differences between the paradigms and their uses are highlighted. Creativity and flexibility are important when deciding on a paradigm. However, consistency and transparency are also needed to ensure the quality and rigour necessary for conducting nursing research. When choosing a suitable paradigm, the researcher should ensure that the ontology, epistemology and methodology of the paradigm are manifest in the methods and research strategies employed.
IR technology for enhanced force protection by AIM
Breiter, R.; Ihle, T.; Rode, W.; Wendler, J.; Rühlich, I.; Haiml, M.; Ziegler, J.
2008-04-01
In all recent missions our forces are faced with various types of asymmetric threads like snipers, IEDs, RPGs or MANPADS. 2 nd and 3 rd Gen IR technology is a backbone of modern force protection by providing situational awareness and accurate target engagement at day/night. 3 rd Gen sensors are developed for thread warning capabilities by use of spectral or spatial information. The progress on a dual-color IR module is discussed in a separate paper [1]. A 1024x256 SWIR array with flexure bearing compressor and pulse tube cold finger provides > 50,000h lifetime for space or airborne hyperspectral imaging in pushbroom geometry with 256 spectral channels for improved change detection and remote sensing of IEDs or chemical agents. Similar concepts are pursued in the LWIR with either spectroscopic imaging or a system of LWIR FPA combined with a cooled tunable Laser to do spectroscopy with stimulated absorption of specific wavelengths. AIM introduced the RangIR sight to match the requirements of sniper teams, AGLs and weapon stations, extending the outstanding optronic performance of the fielded HuntIR with position data of a target by a laser range finder (LRF), a 3 axis digital magnetic compass (DMC) and a ballistic computer for accurate engagement of remote targets. A version with flexure bearing cooler with >30,000h life time is being developed for continuous operation in e.g. gunfire detection systems. This paper gives an overview of AIM's technologies for enhanced force protection.
Philosophy as Inquiry Aimed at the Absolute Knowledge
Directory of Open Access Journals (Sweden)
Ekaterina Snarskaya
2017-09-01
Full Text Available Philosophy as the absolute knowledge has been studied from two different but closely related approaches: historical and logical. The first approach exposes four main stages in the history of European metaphysics that marked out types of “philosophical absolutism”: the evolution of philosophy brought to light metaphysics of being, method, morals and logic. All of them are associated with the names of Aristotle, Bacon/Descartes, Kant and Hegel. Then these forms are considered in the second approach that defined them as subject-matter of philosophy as such. Due to their overall, comprehensive character, the focus of philosophy on them justifies its claim on absoluteness as far as philosophy is aimed at comprehension of the world’s unity regardless of the philosopher’s background, values and other preferences. And that is its prerogative since no other form of consciousness lays down this kind of aim. Thus, philosophy is defined as an everlasting attempt to succeed in conceiving the world in all its multifold manifestations. This article is to try to clarify the claim of philosophy on the absolute knowledge.
Student Teachers’ Attitude towards Twitter for Educational Aims
Directory of Open Access Journals (Sweden)
Victoria I. Marín
2014-07-01
Full Text Available This paper presents an educational experience with 100 student teachers from different courses of the University of the Balearic Islands (Spain in which Twitter is used for various different activities. The aim of this experiment was to explore student teachers’ perceptions in order to value their attitude towards Twitter for educational aims. Afterwards, students were asked to write down their reflections on an eportfolio. Data was collected from their eportfolio evidence, which was analysed to review their attitude towards the use of Twitter for educational purposes and for their future teaching and professional development. The conclusions indicate the need to conduct different educational activities in which Twitter is used in various ways. In addition, conclusions reflect on the real impact of Twitter on students’ learning enhancement, in order to improve student teachers’ attitudes towards social media in education. Therefore, this article contributes to the body of existing research on the use of technology in education, specifically to the possibilities of the use of social media and microblogging in Teacher Education.
OD Matrix Acquisition Based on Mobile Phone Positioning Data
Directory of Open Access Journals (Sweden)
Xiaoqing ZUO
2014-06-01
Full Text Available Dynamic OD matrix is basic data of traffic travel guidance, traffic control, traffic management and traffic planning, and reflects the basic needs of travelers on the traffic network. With the rising popularity of positioning technology and the communication technology and the generation of huge mobile phone users, the mining and use of mobile phone positioning data, can get more traffic intersections and import and export data. These data will be integrated into obtaining the regional OD matrix, which is bound to bring convenience. In this article, mobile phone positioning data used in the data acquisition of intelligent transportation system, research a kind of regional dynamic OD matrix acquisition method based on the mobile phone positioning data. The method based on purpose of transportation, using time series similarity classification algorithm based on piecewise linear representation of the corner point (CP-PLR, mapping each base station cell to traffic zone of different traffic characteristics, and through a series of mapping optimization of base station cell to traffic zone to realize city traffic zone division based on mobile phone traffic data, on the basis, adjacency matrix chosen as the physical data structure of OD matrix storage, the principle of obtaining regional dynamic OD matrix based on the mobile phone positioning data are expounded, and the algorithm of obtaining regional dynamic OD matrix based on mobile phone positioning data are designed and verified.
Enhancing amine terminals in an amine-deprived collagen matrix.
LENUS (Irish Health Repository)
Tiong, William H C
2008-10-21
Collagen, though widely used as a core biomaterial in many clinical applications, is often limited by its rapid degradability which prevents full exploitation of its potential in vivo. Polyamidoamine (PAMAM) dendrimer, a highly branched macromolecule, possesses versatile multiterminal amine surface groups that enable them to be tethered to collagen molecules and enhance their potential. In this study, we hypothesized that incorporation of PAMAM dendrimer in a collagen matrix through cross-linking will result in a durable, cross-linked collagen biomaterial with free -NH 2 groups available for further multi-biomolecular tethering. The aim of this study was to assess the physicochemical properties of a G1 PAMAM cross-linked collagen matrix and its cellular sustainability in vitro. Different amounts of G1 PAMAM dendrimer (5 or 10 mg) were integrated into bovine-derived collagen matrices through a cross-linking process, mediated by 5 or 25 mM 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) in 5 mM N-hydroxysuccinimide (NHS) and 50 mM 2-morpholinoethane sulfonic acid buffer at pH 5.5. The physicochemical properties of resultant matrices were investigated with scanning electron microscopy (SEM), collagenase degradation assay, differential scanning calorimetry (DSC), Fourier transform infrared (FTIR) spectra, and ninhydrin assay. Cellular sustainability of the matrices was assessed with Alamar Blue assay and SEM. There was no significant difference in cellular behavior between the treated and nontreated groups. However, the benefit of incorporating PAMAM in the cross-linking reaction was limited when higher concentrations of either agent were used. These results confirm the hypothesis that PAMAM dendrimer can be incorporated in the collagen cross-linking process in order to modulate the properties of the resulting cross-linked collagen biomaterial with free -NH 2 groups available for multi-biomolecular tethering.
Matrix De Rham Complex and Quantum A-infinity algebras
Barannikov, S.
2014-04-01
I establish the relation of the non-commutative BV-formalism with super-invariant matrix integration. In particular, the non-commutative BV-equation, defining the quantum A ∞-algebras, introduced in Barannikov (Modular operads and non-commutative Batalin-Vilkovisky geometry. IMRN, vol. 2007, rnm075. Max Planck Institute for Mathematics 2006-48, 2007), is represented via de Rham differential acting on the supermatrix spaces related with Bernstein-Leites simple associative algebras with odd trace q( N), and gl( N| N). I also show that the matrix Lagrangians from Barannikov (Noncommutative Batalin-Vilkovisky geometry and matrix integrals. Isaac Newton Institute for Mathematical Sciences, Cambridge University, 2006) are represented by equivariantly closed differential forms.
Did We Get What We Aimed for 10 Years Ago?
Augustinus, A; Moreno, A; Kurepin, A N; De Cataldo, G; Pinazza, O; Rosinský, P; Lechman, M; Jirdén, L S
2011-01-01
The ALICE Detector Control System (DCS) is in charge of control and operation of one of the large high energy physics experiments at CERN in Geneva. The DCS design which started in 2000 was partly inspired by the control systems of the previous generation of HEP experiments at the LEP accelerator at CERN. However, the scale of the LHC experiments and the use of modern, "intelligent" hardware and the harsh operational environment led to an innovative system design. The overall architecture has been largely based on commercial products like PVSS SCADA system and OPC servers extended by frameworks. Windows has been chosen as the operating system platform for the core systems and Linux for the front-end devices. The concept of finite state machines has been deeply integrated into the system design and the design principles have been optimized and adapted to the expected operational needs. The ALICE DCS was designed, prototyped, and developed at a time when no experience with systems of similar s...
An intervention aimed at reducing plagiarism in undergraduate nursing students.
Smedley, Alison; Crawford, Tonia; Cloete, Linda
2015-05-01
Plagiarism is a current and developing problem in the tertiary education sector where students access information and reproduce it as their own. It is identified as occurring in many tertiary level degrees including nursing and allied health profession degrees. Nursing specifically, is a profession where standards and ethics are required and honesty is paramount. The aim of this study was to evaluate the change in nursing student's knowledge and understanding of plagiarism before and after an educational intervention in their first semester of the Bachelor of nursing degree at a private college of higher education in Sydney, Australia. This study concluded that an educational intervention can increase knowledge and awareness of plagiarism among nursing students. Copyright © 2014 Elsevier Ltd. All rights reserved.
Visual Distraction: An Altered Aiming Spatial Response in Dementia
Directory of Open Access Journals (Sweden)
Elizabeth E. Galletta
2012-06-01
Full Text Available Background/Aims: Healthy individuals demonstrate leftward bias on visuospatial tasks such as line bisection, which has been attributed to right brain dominance. We investigated whether this asymmetry occurred in patients with probable dementia of the Alzheimer type (pAD which is associated with neurodegenerative changes affecting temporoparietal regions. Methods: Subjects with pAD and matched controls performed a line bisection task in near and far space under conditions of no distraction, left-sided visual distraction and right-sided visual distraction. Results: Participants with pAD manifested different motor-preparatory ‘aiming’ spatial bias than matched controls. There were significantly greater rightward ‘aiming’ motor-intentional errors both without distraction and with right-sided distraction. Conclusion: ‘Aiming’ motor-preparatory brain activity may be induced by distraction in pAD subjects as compared to typical visual-motor function in controls.
Tracking, aiming, and hitting the UAV with ordinary assault rifle
Racek, František; Baláž, Teodor; Krejčí, Jaroslav; Procházka, Stanislav; Macko, Martin
2017-10-01
The usage small-unmanned aerial vehicles (UAVs) is significantly increasing nowadays. They are being used as a carrier of military spy and reconnaissance devices (taking photos, live video streaming and so on), or as a carrier of potentially dangerous cargo (intended for destruction and killing). Both ways of utilizing the UAV cause the necessity to disable it. From the military point of view, to disable the UAV means to bring it down by a weapon of an ordinary soldier that is the assault rifle. This task can be challenging for the soldier because he needs visually detect and identify the target, track the target visually and aim on the target. The final success of the soldier's mission depends not only on the said visual tasks, but also on the properties of the weapon and ammunition. The paper deals with possible methods of prediction of probability of hitting the UAV targets.
Complementary coordination strategies in a joint Fitts’ reciprocal aiming task
DEFF Research Database (Denmark)
Konvalinka, Ivana; Skewes, Lea; Michael, J.
How do dyads coordinate their actions to achieve a common goal when one person has the more difficult task? In the present study, dyads were instructed to engage in a Fitts’s reciprocal aiming task as accurately as possible, and at a given tempo sent through their headphones. They were in conditi...... a joint goal, by taking on leader-follower roles....... was assigned to either the target’s role – with varying target width, and hence task difficulty – or the reference role – with the widest (easiest) target. Results show that when the task was performed interactively with the other person, they were most synchronized, and also used the target most similarly......, while compromising rhythmic accuracy. In addition, as task difficulty increased for the member with the target’s role, the participant with the reference role became more adaptive to her tempo. This suggests that interacting members of a dyad optimally negotiate coordination strategies to achieve...
Microwave dielectric absorption spectroscopy aiming at novel dosimetry using DNAs
Energy Technology Data Exchange (ETDEWEB)
Izumi, Yoshinobu; Hirayama, Makoto; Matuo, Youichirou [Research Institute of Nuclear Engineering, University of Fukui, Fukui (Japan); Sunagawa, Takeyoshi [Fukui University of Technology, Fukui (Japan)
2017-03-15
We are developing L-band and S-band microwave dielectric absorption systems aiming novel dosimetry using DNAs, such as plasmid DNA and genomic DNA, and microwave technology. Each system is composed of a cavity resonator, analog signal generator, circulator, power meter, and oscilloscope. Since the cavity resonator is sensitive to temperature change, we have made great efforts to prevent the fluctuation of temperature. We have developed software for controlling and measurement. By using this system, we can measure the resonance frequency, f, and ΔQ (Q is a dimensionless parameter that describes how under-damped an oscillator or resonator is, and characterizes a resonator’s bandwidth relative to its center frequency) within about 3 minutes with high accuracy. This system will be expected to be applicable to DNAs evaluations and to novel dosimetric system.
Characterization of electric arc furnace dust aiming reuse
International Nuclear Information System (INIS)
Grillo, F.F.; Oliveira, E.B.G.; Oliveira, J.R. de; Telles, V.B.; Tenorio, J.A.S.
2010-01-01
This work aims to study the characterize of steelmaking dust, from the primary refining of steel in Electric Arc Furnace, in order to verify feasibility of reuse through the addition of hot metal in the form of briquette. The techniques used to characterize the dust was chemical analyses, size separation tests, X-ray diffraction analyses (XRD), Scanning Electron Microscopy (SEM). After characterization, was the calculation of reductant considering the complete reduction of iron oxides and then to briquetting. The waste sample is composed essentially of spherical particles and has a very small particle size (85% below 10 μm). The XRD has presented compounds such as ZnFe 2 O 4 , Fe 3 O 4 , ZnO e SiO 2 . This work showed that its possible recovery approximately 92% of metal iron from dust generated during steelmaking.This (author)
Advanced Industrial Materials (AIM) Program. Annual progress report, FY 1994
Energy Technology Data Exchange (ETDEWEB)
Sorrell, C.A.
1995-05-01
The Advanced Industrial Materials Program is a part of the Office of Industrial Technologies (OIT), Energy Efficiency and Renewable Energy in the Department of Energy. The mission of the AIM Program is to conduct applied research, development, and applications engineering work, in partnership with industry, to commercialize new or improved materials and materials processing methods that will improve energy efficiency, productivity, and competitiveness. AIM is responsible for identifying, supporting, and coordinating multidisciplinary projects to solve identified industrial needs and transferring the technology to the industrial sector. Program investigators in the DOE National Laboratories are working closely with approximately 100 companies, including 15 partners in Cooperative Research and Development Agreements. Work is being done in a wide variety of materials technologies, including intermetallic alloys, ceramic composites, metal composites, polymers, engineered porous materials, and surface modification. The Program supports other efforts in the Office of Industrial Technologies to assist the energy consuming process industries, including forest products, glass, steel, aluminum, foundries, chemicals, and refineries. To support OITs {open_quotes}Industries of the Future{close_quotes} initiatives and to improve the relevance of materials research, assessments of materials needs and opportunities in the process industries are being made. These assessments are being used for program planning and priority setting; support of work to satisfy those needs is being provided. Many new materials that have come into the marketplace in recent years, or that will be available for commercial use within a few more years, offer substantial benefits to society. This document contains 28 reports on advanced materials research. Individual reports have been processed separately for entry onto the Department of Energy databases.
Oehlmann, Dietmar; Ohlmann, Odile M.; Danzebrink, Hans U.
2005-04-01
perform this exchange, as a matrix, understood as source, of new ideas.
Analytical techniques for instrument design - matrix methods
International Nuclear Information System (INIS)
Robinson, R.A.
1997-01-01
We take the traditional Cooper-Nathans approach, as has been applied for many years for steady-state triple-axis spectrometers, and consider its generalisation to other inelastic scattering spectrometers. This involves a number of simple manipulations of exponentials of quadratic forms. In particular, we discuss a toolbox of matrix manipulations that can be performed on the 6- dimensional Cooper-Nathans matrix: diagonalisation (Moller-Nielsen method), coordinate changes e.g. from (Δk I ,Δk F to ΔE, ΔQ ampersand 2 dummy variables), integration of one or more variables (e.g. over such dummy variables), integration subject to linear constraints (e.g. Bragg's Law for analysers), inversion to give the variance-covariance matrix, and so on. We show how these tools can be combined to solve a number of important problems, within the narrow-band limit and the gaussian approximation. We will argue that a generalised program that can handle multiple different spectrometers could (and should) be written in parallel to the Monte-Carlo packages that are becoming available. We will also discuss the complementarity between detailed Monte-Carlo calculations and the approach presented here. In particular, Monte-Carlo methods traditionally simulate the real experiment as performed in practice, given a model scattering law, while the Cooper-Nathans method asks the inverse question: given that a neutron turns up in a particular spectrometer configuration (e.g. angle and time of flight), what is the probability distribution of possible scattering events at the sample? The Monte-Carlo approach could be applied in the same spirit to this question
Venter, Petrus J.; Bogalecki, Alfons W.; du Plessis, Monuko; Goosen, Marius E.; Nell, Ilse J.; Rademeyer, P.
2011-03-01
Display technologies always seem to find a wide range of interesting applications. As devices develop towards miniaturization, niche applications for small displays may emerge. While OLEDs and LCDs dominate the market for small displays, they have some shortcomings as relatively expensive technologies. Although CMOS is certainly not the dominating semiconductor for photonics, its widespread use, favourable cost and robustness present an attractive potential if it could find application in the microdisplay environment. Advances in improving the quantum efficiency of avalanche electroluminescence and the favourable spectral characteristics of light generated through the said mechanism may afford CMOS the possibility to be used as a display technology. This work shows that it is possible to integrate a fully functional display in a completely standard CMOS technology mainly geared towards digital design while using light sources completely compatible with the process and without any post processing required.
Glomerular matrix: synthesis, turnover and role in mesangial expansion
DEFF Research Database (Denmark)
Couchman, J R; Beavan, L A; McCarthy, K J
1994-01-01
The extracellular matrix has an integral role in development, homeostasis and pathology of the glomerulus. Three spatially distinct matrices are present in the glomerulus: the mesangium, and basement membranes of the capillary loops and Bowman's capsule. Each is dominated by basement membrane com...
The S-matrix for abstract scattering systems
International Nuclear Information System (INIS)
Amrein, W.O.; Pearson, D.B.
1979-01-01
Let S(lambda) be the S-matrix at energy lambda for an abstract scattering system. A bound is derived in terms of the interaction, on integrals of the form ∫ h(lambda)/S(lambda) - I/ 2 sub(HS) dlambda, where /./sub(HS) denotes the Hilbert-Schmidt norm. (Auth.)
The imaging performance of flash memory masks characterized with AIMS
van Setten, Eelco; Wismans, Onno; Grim, Kees; Finders, Jo; Dusa, Mircea; Birkner, Robert; Richter, Rigo; Scherübl, Thomas
2009-04-01
Flash memory is an important driver of the lithography roadmap, with its dramatic acceleration in dimensional shrink, pushing for ever smaller feature sizes. The introduction of hyper-NA immersion lithography has brought the 45nm node and below within reach for memory makers using single exposure. At these feature sizes mask topology and the material properties of the film stack on the mask play an important role on imaging performance. Furthermore, the break up of the array pitch regularity in the NAND-type flash memory cell by two thick wordlines and a central space, leads to feature-center placement (overlay) errors, that are inherent to the design. An integral optimization approach is needed to mitigate these effects and to control both the CD and placement errors tightly. In this paper we will show that aerial image measurements at mask-level are useful for characterizing the gate layer of a NAND-Flash design before exposure. The aerial image measurements are performed with the AIMSTM 45-193i. and compared to CD measurements on the wafer obtained with an XT:1900Gi hyper-NA immersion system. An excellent correlation is demonstrated for feature-center placement errors and CD variations across the mask (see Figure 1) for several features in the gate layer down to 40nm half pitch. This shows the potential to use aerial image measurements at mask-level in combination with correction techniques on the photomask, like the CDC200 tool in combination with exposure tool correction techniques, such as DoseMapperTM, to improve both across field and across wafer CD uniformity of critical layers.
Measuring methods of matrix diffusion
International Nuclear Information System (INIS)
Muurinen, A.; Valkiainen, M.
1988-03-01
In Finland the spent nuclear fuel is planned to be disposed of at large depths in crystalline bedrock. The radionuclides which are dissolved in the groundwater may be able to diffuse into the micropores of the porous rock matrix and thus be withdrawn from the flowing water in the fractures. This phenomenon is called matrix diffusion. A review over matrix diffusion is presented in the study. The main interest is directed to the diffusion of non-sorbing species. The review covers diffusion experiments and measurements of porosity, pore size, specific surface area and water permeability
Maximal quantum Fisher information matrix
International Nuclear Information System (INIS)
Chen, Yu; Yuan, Haidong
2017-01-01
We study the existence of the maximal quantum Fisher information matrix in the multi-parameter quantum estimation, which bounds the ultimate precision limit. We show that when the maximal quantum Fisher information matrix exists, it can be directly obtained from the underlying dynamics. Examples are then provided to demonstrate the usefulness of the maximal quantum Fisher information matrix by deriving various trade-off relations in multi-parameter quantum estimation and obtaining the bounds for the scalings of the precision limit. (paper)
Directory of Open Access Journals (Sweden)
ORHAN ELMACI
2014-06-01
Full Text Available The present study intended to investigate the “Balance Scorecard (BSC model integrated with Resource Consumption Accounting (RCA” which helps to evaluate the enterprise as matrix structure in its all parts. It aims to measure how much tangible and intangible values (assets of enterprises contribute to the enterprises. In other words, it measures how effectively, actively, and efficiently these values (assets are used. In short, it aims to measure sustainable competency of enterprises. As expressing the effect of tangible and intangible values (assets of the enterprise on the performance in mathematical and statistical methods is insufficient, it is targeted that RCA Method integrated with BSC model is based on matrix structure and control models. The effects of all complex factors in the enterprise on the performance (productivity and efficiency estimated algorithmically with cause and effect diagram. The contributions of matrix structures for reaching the management functional targets of the enterprises that operate in market competitive environment increasing day to day, is discussed. So in the context of modern management theories, as a contribution to BSC approach which is in the foreground in today’s administrative science of enterprises in matrix organizational structures, multidimensional performance evaluation model -RCA integrated with BSC Model proposal- is presented as strategic planning and strategic evaluation instrument.
[Social marketing--seduction with the aim of healthy behavior?].
Loss, J; Nagel, E
2010-01-01
SOCIAL MARKETING - SEDUCTION WITH THE AIM OF HEALTHY BEHAVIOR? Social marketing is the use of marketing principles to design and implement programs that promote socially beneficial behaviour change. Contrary to the marketing of consumption goods, social marketing does not deal with material products, but with behaviour, e. g. not smoking. This 'product' has a basic benefit (i. e. reduction of health risks in the long run), which is, however, difficult to convey. Therefore, the intended change in behaviour has to be related to a further reward which consists of symbolic goods, e. g. social appreciation or a better body feeling. The communication policy is essential for information on and motivation for the preventive issue. Social marketing campaigns whose development and management follow the principles of classical marketing can render preventive efforts more effective. In addition, social marketing can lead to a better quality management as compared to conventional preventive activities. These advantages can be explained by a) tailoring the campaign more specifically to the target group's needs and motives, b) presenting health risks more convincingly, and c) continuously analysing and evaluating the campaign and its effects. On the other hand, the marketing of preventive aims through mass media can bear several risks, as exemplified by different national and international public health campaigns. The necessity to communicate briefly and succinctly can lead to misleading simplifications and, in case of cancer screening, to the trivialization of a behaviour's consequences and adverse effects. Also, many campaigns do not intend to educate and inform, but try to persuade target persons of a certain behaviour, using emotions such as fear. This has led to social marketing being criticized as manipulation. Sometimes, social marketing campaigns cause stigma and discrimination of certain population subgroups, e. g. obese or HIV-positive people. Health promoters who plan
Fluency: an aim in teaching and a criterion in assessment
Directory of Open Access Journals (Sweden)
Aud Marit Simensen
2010-05-01
Full Text Available This article investigates the concept ‘fluency’ from different perspectives. When fluency is an aim in teaching, a thorough comprehension of the concept among teachers is a prerequisite for appropriate planning of instruction, including the choice of appropriate classroom activities. When fluency is an assessment criterion, it is even more important that examiners have a shared perception of the concept. The present article starts by presenting common perceptions of the concept and goes on to explore some of the current research. Next, it provides a historical overview of the place of fluency in teaching theory and explains some of the preconditions for the inclusion of this concept among teaching objectives and assessment criteria. It will also, as an illustration, give an outline of the position of the concept over time in the Norwegian school system on the basis of an analysis of the relevant syllabuses. Finally, the article explicates the notion of language use as a complex cognitive skill and explores current method¬ological ideas about teaching towards fluency.
The AI&M procedure for learning from incomplete data
DEFF Research Database (Denmark)
Jaeger, Manfred
2006-01-01
We investigate methods for parameter learning from incomplete data that is not missing at random. Likelihood-based methods then require the optimization of a profile likelihood that takes all possible missingness mechanisms into account. Optimizing this profile likelihood poses two main difficult......We investigate methods for parameter learning from incomplete data that is not missing at random. Likelihood-based methods then require the optimization of a profile likelihood that takes all possible missingness mechanisms into account. Optimizing this profile likelihood poses two main...... by operations in the space of data completions, rather than directly in the parameter space of the profile likelihood. We apply the AI\\&M method to learning parameters for Bayesian networks. The method is compared against conservative inference, which takes into account each possible data completion......, and against EM. The results indicate that likelihood-based inference is still feasible in the case of unknown missingness mechanisms, and that conservative inference is unnecessarily weak. On the other hand, our results also provide evidence that the EM algorithm is still quite effective when the data...
Motivation, procedures and aims of reacting plasma experiments
International Nuclear Information System (INIS)
Miyahara, Akira
1982-01-01
A project of reacting plasma experiment (R-project) was proposed at the Institute of Plasma Physics (IPP), Nagoya University. It is necessary to bridge plasma physics and fusion engineering by means of a messenger wire like burning plasma experiment. This is a motivation of the R-project. The university linkage organization of Japan for fusion engineering category carried out a lot of contribution to R-tokamak design. The project consists of four items, namely, R-tokamak design, research and development (R and D), site and facilities, and international collaboration. The phase 1 experiment (R 1 - phase) corresponds to burning plasma experiment without D + T fuel, while the phase-2 experiment (R 2 -phase) with D + T fuel. One reference design was finished. Intensive efforts have been carried out by the R and D team on the following items, wall material, vacuum system, tritium system, neutronics, remote control system, pulsed superconducting magnet development, negative ion source, and alpha-particle diagnostics. The problems concerning site and major facilities are also important, because tritium handling, neutron and gamma-ray sky shines and the activation of devices cause impact to surrounding area. The aims of burning plasma experiment are to enter tritium into the fusion device, and to study burning plasma physics. (Kato, T.)
Ecolabel and ecodesign. Aims impossible for small and medium companies?
International Nuclear Information System (INIS)
Luciani, R.; Andriola, L.; Masoni, P.
2000-01-01
It is commonly held by now that a policy of sustainable development in the production sector cannot be faced in terms of simply reducing the environmental impact at the end of the production chain but should be imprinted with a preventive approach which, intervening on the production cycles and the products themselves, helps minimize pressure on the environment. To be competitive manufacturing industry must contribute a determinant amount to sustainable development by reducing the material content of products and increasing their use value, through processes and products-services that are innovative, safer, cleaner and based on a low use of natural resources. To be effective and avoid merely shifting the problem, this work should not be aimed at the level of individual plants or industries but be broadly planned, taking into account the entire value chain and hence the product's whole life-cycle. In addition, support should be given to small and medium-sized companies that characterize Italian production, because they find it hard to use the tools of a product policy originally ideated for big business [it
Alginate Immobilization of Metabolic Enzymes (AIME) for High ...
Alginate Immobilization of Metabolic Enzymes (AIME) for High-Throughput Screening Assays DE DeGroot, RS Thomas, and SO SimmonsNational Center for Computational Toxicology, US EPA, Research Triangle Park, NC USAThe EPA’s ToxCast program utilizes a wide variety of high-throughput screening (HTS) assays to assess chemical perturbations of molecular and cellular endpoints. A key criticism of using HTS assays for toxicity assessment is the lack of xenobiotic metabolism (XM) which precludes both metabolic detoxification as well as bioactivation of chemicals tested in vitro thereby mischaracterizing the potential risk posed by these chemicals. To address this deficiency, we have developed an extracellular platform to retrofit existing HTS assays with XM activity. This platform utilizes the S9 fraction of liver homogenate encapsulated in an alginate gel network which reduces the cytotoxicity caused by direct addition of S9 to cells in culture. Alginate microspheres containing encapsulated human liver S9 were cross-linked to solid supports extending from a 96-well plate lid and were assayed using a pro-luciferin substrate specific for CYP3A4 (IPA). We demonstrate that S9 was successfully encapsulated and remained enzymatically active post-encapsulation with 5-10X the CYP3A4 activity as compared to 1 µg solubilized human liver S9. Ketoconazole, a known inhibitor of human CYP3A4, inhibited CYP3A4 activity in a concentration-dependent manner (IC50: 0.27 µM) and inhibiti
A resolution of the integration region problem for the supermoduli space integral
Davis, Simon
2014-12-01
The integration region of the supermoduli space integral is defined in the super-Schottky group parametrization. The conditions on the super-period matrix elements are translated to relations on the parameters. An estimate of the superstring amplitude at arbitrary genus is sufficient for an evaluation of the cross-section to all orders in the expansion of the scattering matrix.
Towards rebuilding vaginal support utilizing an extracellular matrix bioscaffold.
Liang, Rui; Knight, Katrina; Easley, Deanna; Palcsey, Stacy; Abramowitch, Steven; Moalli, Pamela A
2017-07-15
As an alternative to polypropylene mesh, we explored an extracellular matrix (ECM) bioscaffold derived from urinary bladder matrix (MatriStem™) in the repair of vaginal prolapse. We aimed to restore disrupted vaginal support simulating application via transvaginal and transabdominal approaches in a macaque model focusing on the impact on vaginal structure, function, and the host immune response. In 16 macaques, after laparotomy, the uterosacral ligaments and paravaginal attachments to pelvic side wall were completely transected (IACUC# 13081928). 6-ply MatriStem was cut into posterior and anterior templates with a portion covering the vagina and arms simulating uterosacral ligaments and paravaginal attachments, respectively. After surgically exposing the correct anatomical sites, in 8 animals, a vaginal incision was made on the anterior and posterior vagina and the respective scaffolds were passed into the vagina via these incisions (transvaginal insertion) prior to placement. The remaining 8 animals underwent the same surgery without vaginal incisions (transabdominal insertion). Three months post implantation, firm tissue bands extending from vagina to pelvic side wall appeared in both MatriStem groups. Experimental endpoints examining impact of MatriStem on the vagina demonstrated that vaginal biochemical and biomechanical parameters, smooth muscle thickness and contractility, and immune responses were similar in the MatriStem no incision group and sham-operated controls. In the MatriStem incision group, a 41% decrease in vaginal stiffness (P=0.042), a 22% decrease in collagen content (P=0.008) and a 25% increase in collagen subtypes III/I was observed vs. Sham. Active MMP2 was increased in both Matristem groups vs. Sham (both P=0.002). This study presents a novel application of ECM bioscaffolds as a first step towards the rebuilding of vaginal support. Pelvic organ prolapse is a common condition related to failure of the supportive soft tissues of the vagina
Chan, Garnet Kin-Lic; Keselman, Anna; Nakatani, Naoki; Li, Zhendong; White, Steven R.
2016-07-01
Current descriptions of the ab initio density matrix renormalization group (DMRG) algorithm use two superficially different languages: an older language of the renormalization group and renormalized operators, and a more recent language of matrix product states and matrix product operators. The same algorithm can appear dramatically different when written in the two different vocabularies. In this work, we carefully describe the translation between the two languages in several contexts. First, we describe how to efficiently implement the ab initio DMRG sweep using a matrix product operator based code, and the equivalence to the original renormalized operator implementation. Next we describe how to implement the general matrix product operator/matrix product state algebra within a pure renormalized operator-based DMRG code. Finally, we discuss two improvements of the ab initio DMRG sweep algorithm motivated by matrix product operator language: Hamiltonian compression, and a sum over operators representation that allows for perfect computational parallelism. The connections and correspondences described here serve to link the future developments with the past and are important in the efficient implementation of continuing advances in ab initio DMRG and related algorithms.
In vivo imaging of extracellular matrix remodeling by tumor-associated fibroblasts
DEFF Research Database (Denmark)
Perentes, Jean Y; McKee, Trevor D; Ley, Carsten D
2009-01-01
Here we integrated multiphoton laser scanning microscopy and the registration of second harmonic generation images of collagen fibers to overcome difficulties in tracking stromal cell-matrix interactions for several days in live mice. We show that the matrix-modifying hormone relaxin increased...... tumor-associated fibroblast (TAF) interaction with collagen fibers by stimulating beta1-integrin activity, which is necessary for fiber remodeling by matrix metalloproteinases....
Some Comments on Quasi-Birth-and-Death Processes and Matrix Measures
Directory of Open Access Journals (Sweden)
Holger Dette
2010-01-01
Full Text Available We explore the relation between matrix measures and quasi-birth-and-death processes. We derive an integral representation of the transition function in terms of a matrix-valued spectral measure and corresponding orthogonal matrix polynomials. We characterize several stochastic properties of quasi-birth-and-death processes by means of this matrixmeasure and illustrate the theoretical results by several examples.
Cathodic Polarization Coats Titanium Based Implant Materials with Enamel Matrix Derivate (EMD
Directory of Open Access Journals (Sweden)
Matthias J. Frank
2014-03-01
Full Text Available The idea of a bioactive surface coating that enhances bone healing and bone growth is a strong focus of on-going research for bone implant materials. Enamel matrix derivate (EMD is well documented to support bone regeneration and activates growth of mesenchymal tissues. Thus, it is a prime candidate for coating of existing implant surfaces. The aim of this study was to show that cathodic polarization can be used for coating commercially available implant surfaces with an immobilized but functional and bio-available surface layer of EMD. After coating, XPS revealed EMD-related bindings on the surface while SIMS showed incorporation of EMD into the surface. The hydride layer of the original surface could be activated for coating in an integrated one-step process that did not require any pre-treatment of the surface. SEM images showed nano-spheres and nano-rods on coated surfaces that were EMD-related. Moreover, the surface roughness remained unchanged after coating, as it was shown by optical profilometry. The mass peaks observed in the matrix-assisted laser desorption/ionization time-of-flight mass spectroscopy (MALDI-TOF MS analysis confirmed the integrity of EMD after coating. Assessment of the bioavailability suggested that the modified surfaces were active for osteoblast like MC3M3-E1 cells in showing enhanced Coll-1 gene expression and ALP activity.
National Oceanic and Atmospheric Administration, Department of Commerce — This data set was taken from CRD 08-18 at the NEFSC. Specifically, the Gulf of Maine diet matrix was developed for the EMAX exercise described in that center...
Electromagnetic matrix elements in baryons
International Nuclear Information System (INIS)
Lipkin, H.J.; Moinester, M.A.
1992-01-01
Some simple symmetry relations between matrix elements of electromagnetic operators are investigated. The implications are discussed for experiments to study hyperon radiative transitions and polarizabilities and form factors. (orig.)
International Nuclear Information System (INIS)
Descouvemont, P; Baye, D
2010-01-01
The different facets of the R-matrix method are presented pedagogically in a general framework. Two variants have been developed over the years: (i) The 'calculable' R-matrix method is a calculational tool to derive scattering properties from the Schroedinger equation in a large variety of physical problems. It was developed rather independently in atomic and nuclear physics with too little mutual influence. (ii) The 'phenomenological' R-matrix method is a technique to parametrize various types of cross sections. It was mainly (or uniquely) used in nuclear physics. Both directions are explained by starting from the simple problem of scattering by a potential. They are illustrated by simple examples in nuclear and atomic physics. In addition to elastic scattering, the R-matrix formalism is applied to inelastic and radiative-capture reactions. We also present more recent and more ambitious applications of the theory in nuclear physics.
Random matrix improved subspace clustering
Couillet, Romain; Kammoun, Abla
2017-01-01
This article introduces a spectral method for statistical subspace clustering. The method is built upon standard kernel spectral clustering techniques, however carefully tuned by theoretical understanding arising from random matrix findings. We show
Interventions aiming to reduce early retirement due to rheumatic diseases
Directory of Open Access Journals (Sweden)
Pedro Almeida Laires
2017-07-01
Full Text Available Introduction: Aging of the population and early retirement translates into productivity losses to society. Persistence of working life is crucial to counteract this sustainability issue faced by western countries. Musculoskeletal and rheumatic diseases (RD may cause work disability and early exit from work, including early retirement. The objective of this article is to review the current knowledge about interventions aiming to reduce early retirement due to RD. Methods: We searched PubMed and The Cochrane Library for studies either in English or Portuguese between January 2000 and June 2016 that evaluated the impact of interventions targeting early retirement in RD patients still at work. We also searched for grey literature from Portuguese institutional repositories. Results: We identified several published studies testing pharmacologic and non-pharmacologic vocational rehabilitation interventions. None was specifically identified for Portugal. The general low quality of the literature and its inconsistency makes it unfeasible to draw definitive conclusions. However, some broad recommendations might be outlined. An effective intervention must: 1 act upon different levels (e.g. RD patient, workplace, involving several stakeholders (e.g. rheumatologists, occupational physicians, employers; 2 prioritize the right patients (e.g. more disabling RD; and 3 consider the patients’ role, for instance by including an element of patient education and support. Despite the lack of good quality evidence on this field, there seems to be a growing interest in the international scientific community with several ongoing studies promoting such interventions. This promising data will be very useful to set up effective policies. Conclusions: This article summarizes the current knowledge about the impact of interventions to avoid or mitigate early retirement in RD patients. It highlights the demand for further research and it also contributes to aware decision
SaudiVeg ecoinformatics: Aims, current status and perspectives
Directory of Open Access Journals (Sweden)
Mohamed A. El-Sheikh
2017-02-01
Full Text Available During the last decade many electronic databases of vegetation plots were established in many countries around the world. These databases contain valuable phytosociological information assisting both governmental and NGO (Non-governmental organizations agencies to formulate strategies and on-ground plans to manage and protect nature resources. This paper provides an account on aims, current status and perspectives of building of a vegetation database for the Central Region (Najd of Saudi Arabia – the founding element of the Saudi Vegetation Database (SVD. The data stored by the database are sample plots (vegetation relevés collected according to the field techniques of the Braun-Blanquet approach (lists of taxa accompanied by semi-quantitative cover assessment, and are accompanied by general vegetation characteristics such as vegetation layering and cover, information on life-form of the recorded species, geographical coordinates, altitude, soil typology, topography and many more. More than 2900 vegetation-plot records (relevés have so far been collected in the Najd region; of these more than 2000 have already been stored using the Turboveg database platform. These field records cover many habitats such as depressions, wadis (dry river beds, agricultural lands, sand dunes, sabkhas, and ruderal habitats. The ecological information collected in the database is currently the largest set of vegetation data collated into a database in the Middle East. These data are of great importance for biodiversity studies in Saudi Arabia, since the region is recording a loss of biodiversity at a fast rate due to environmental problems such as global warming and land-use changes. We envisage that this database would catalyze further data collection on vegetation of the entire Arabian Peninsula, and shall serve as one of the most important datasets for classification and mapping of the vegetation of the Kingdom of Saudi Arabia.
Matrix Effects in XRF Measurements
International Nuclear Information System (INIS)
Kandil, A.T.; Gabr, N.A.; El-Aryan, S.M.
2015-01-01
This research treats the matrix effect on XRF measurements. The problem is treated by preparing general oxide program, which contains many samples that represent all materials in cement factories, then by using T rail Lachance m ethod to correct errors of matrix effect. This work compares the effect of using lithium tetraborate or sodium tetraborate as a fluxing agent in terms of accuracy and economic cost
Matrix analysis of electrical machinery
Hancock, N N
2013-01-01
Matrix Analysis of Electrical Machinery, Second Edition is a 14-chapter edition that covers the systematic analysis of electrical machinery performance. This edition discusses the principles of various mathematical operations and their application to electrical machinery performance calculations. The introductory chapters deal with the matrix representation of algebraic equations and their application to static electrical networks. The following chapters describe the fundamentals of different transformers and rotating machines and present torque analysis in terms of the currents based on the p
Staggered chiral random matrix theory
International Nuclear Information System (INIS)
Osborn, James C.
2011-01-01
We present a random matrix theory for the staggered lattice QCD Dirac operator. The staggered random matrix theory is equivalent to the zero-momentum limit of the staggered chiral Lagrangian and includes all taste breaking terms at their leading order. This is an extension of previous work which only included some of the taste breaking terms. We will also present some results for the taste breaking contributions to the partition function and the Dirac eigenvalues.
The association between patient-therapist MATRIX congruence and treatment outcome.
Mendlovic, Shlomo; Saad, Amit; Roll, Uri; Ben Yehuda, Ariel; Tuval-Mashiah, Rivka; Atzil-Slonim, Dana
2018-03-14
The present study aimed to examine the association between patient-therapist micro-level congruence/incongruence ratio and psychotherapeutic outcome. Nine good- and nine poor-outcome psychodynamic treatments (segregated by comparing pre- and post-treatment BDI-II) were analyzed (N = 18) moment by moment using the MATRIX (total number of MATRIX codes analyzed = 11,125). MATRIX congruence was defined as similar adjacent MATRIX codes. the congruence/incongruence ratio tended to increase as the treatment progressed only in good-outcome treatments. Progression of MATRIX codes' congruence/incongruence ratio is associated with good outcome of psychotherapy.
Straight sinus: ultrastructural analysis aimed at surgical tumor resection.
Amato, Marcelo Campos Moraes; Tirapelli, Luis Fernando; Carlotti, Carlos Gilberto; Colli, Benedicto Oscar
2016-08-01
OBJECTIVE Accurate knowledge of the anatomy of the straight sinus (SS) is relevant for surgical purposes. During one surgical procedure involving the removal of part of the SS wall, the authors observed that the venous blood flow was maintained in the SS, possibly through a vein-like structure within the dural sinus or dural multiple layers. This observation and its divergence from descriptions of the histological features of the SS walls motivated the present study. The authors aimed to investigate whether it is possible to dissect the SS walls while keeping the lumen intact, and to describe the histological and ultrastructural composition of the SS wall. METHODS A total of 22 cadaveric specimens were used. The SS was divided into three portions: anterior, middle, and posterior. The characteristics of the SS walls were analyzed, and the feasibility of dissecting them while keeping the SS lumen intact was assessed. The thickness and the number of collagen fibers and other tissues in the SS walls were compared with the same variables in other venous sinuses. Masson's trichrome and Verhoeff's stains were used to assess collagen and elastic fibers, respectively. The data were analyzed using Zeiss image analysis software (KS400). RESULTS A vein-like structure independent of the SS walls was found in at least one of the portions of the SS in 8 of 22 samples (36.36%). The inferior wall could be delaminated in at least one portion in 21 of 22 samples (95.45%), whereas the lateral walls could seldom be delaminated. The inferior wall of the SS was thicker (p < 0.05) and exhibited less collagen and greater amounts of other tissues-including elastic fibers, connective tissue, blood vessels, and nerve fibers (p < 0.05)-compared with the lateral walls. Transmission electron microscopy revealed the presence of muscle fibers at a level deeper than that of the subendothelial connective tissue in the inferior wall of the SS, extending from its junction with the great cerebral vein
Aiming for cure in HBV and HDV infection.
Petersen, Jörg; Thompson, Alexander J; Levrero, Massimo
2016-10-01
Chronic hepatitis B virus (HBV) infection continues to be a major health burden worldwide. Currently available antiviral treatment options for chronic hepatitis B include pegylated interferon alpha2a (PegIFN) or nucleos(t)ide analogues (NAs). The major advantages of NAs are good tolerance and potent antiviral activity associated with high rates of sustained on-treatment response to therapy. The advantages of PegIFN include a finite course of treatment, the absence of drug resistance, and an opportunity to obtain a durable post-treatment response to therapy. Furthermore, PegIFN is the only approved agent known to be active against hepatitis D virus (HDV). The use of these two antiviral agents with different mechanisms of action in combination against hepatitis B is theoretically an attractive approach for treatment. Although several studies have confirmed certain virological advantages of combination therapies, data supporting a long-term clinical benefit for patients are lacking and monotherapy with PegIFN or NAs remains the therapy of choice. Moreover, with the current treatment approaches, only a limited number of patients achieve hepatitis B surface antigen (HBsAg) loss. HBsAg loss is considered a "functional cure", but does not mean viral eradication. There is a need for novel therapeutic approaches that enable not only suppression of viral replication, but resolution of HBV infection. A key challenge is to target covalently closed circular DNA (cccDNA) in the nucleus of infected hepatocytes. The recent development and availability of innovative in vitro and in vivo systems and sensitive molecular techniques has opened new possibilities to study the complex network of interactions that HBV establishes with the host in the course of infection and to define new targets for antiviral strategies. Several new antiviral or immunomodulatory compounds have reached preclinical or clinical testing with the aim of silencing or eradicating cccDNA to achieve functional cure
Nisin Production Utilizing Skimmed Milk Aiming to Reduce Process Cost
Jozala, Angela Faustino; de Andrade, Maura Sayuri; de Arauz, Luciana Juncioni; Pessoa, Adalberto; Penna, Thereza Christina Vessoni
Nisin is a natural additive for conservation of food, pharmaceutical, and dental products and can be used as a therapeutic agent. Nisin inhibits the outgrowth of spores, the growth of a variety of Gram-positive and Gram-negative bacteria. This study was performed to optimize large-scale nisin production in skimmed milk and subproducts aiming at low-costs process and stimulating its utilization. Lactococcus lactis American Type Culture Collection (ATCC) 11454 was developed in a rotary shaker (30°C/36 h/100 rpm) in diluted skimmed milk and nisin activity, growth parameters, and media components were also studied. Nisin activity in growth media was expressed in arbitrary units (AU/mL) and converted to standard nisin concentration (Nisaplin®, 25 mg of pure nisin is 1.0×106 AU/mL). Nisin activity in skimmed milk 2.27 gtotal solids was up to threefold higher than transfers in skimmed milk 4.54 gtotal solids and was up to 85-fold higher than transfers in skimmed milk 1.14 gtotal solids. L. lactis was assayed in a New Brunswick fermentor with 1.5 L of diluted skimmed milk (2.27 gtotal solids) and airflow of 1.5 mL/min (30°C/36/200 rpm), without pH control. In this condition nisin activity was observed after 4 h (45.07 AU/mL) and in the end of 36 h process (3312.07 AU/mL). This work shows the utilization of a low-cost growth medium (diluted skimmed milk) to nisin production with wide applications. Furthermore, milk subproducts (milk whey) can be exploited in nisin production, because in Brazil 50% of milk whey is disposed with no treatment in rivers and because of high organic matter concentrations it is considered an important pollutant. In this particular case an optimized production of an antimicrobial would be lined up with industrial disposal recycling.
Aiming at Targets: The Autobiography of Robert C. Seamans, Jr.
Seamans, Robert C., Jr.
1996-01-01
Bob Seamans originally was inspired to write this book for his family and friends. That is a large audience. By his own count his immediate family numbers twenty-four, not counting brothers and cousins and their families. His friends are uncounted but surely run to hundreds. As one of them and as a colleague at NASA, I am pleased and honored that he asked me to write this foreword. While written in Bob's unique and informal style, this autobiography has significance for many readers beyond his large circles of family and friends. Leaders and students of large, complex technological endeavors should be able to learn much from reading how Bob faced the daunting technical and management challenges in his career. As the title of this book implies, Bob has always set high goals for himself and then kept his eyes focused on both the necessary details and the broader picture. His ability to shift smoothly among jobs that required seemingly disparate abilities and skills speaks volumes about his insight, dedication, and enthusiasm for achievement. The book spans a truly remarkable life story. Bob first takes us through his growing up, education, and early professional and family life. Next he focuses on the crucial years when he was the general manager of NASA. Then he moves on to his career in the top jobs at the Air Force, the National Academy of Engineering, and the Energy Research and Development Administration. Finally, he touches on his later leadership activities in the academic and business worlds. Aiming at Targets is a series of fascinating topical vignettes covering his professional life. Taken together, like broad brushstrokes in an impressionist painting, they give a better picture of Bob Seamans and his work than a detailed recitation of facts and dates could hope to do. This is a cheerful account of an interesting and successful career. The book is full of good stories, with many memorable characters. Like the proverbial sundial, it counts the sunny hours
Lie Algebras and Integrable Systems
International Nuclear Information System (INIS)
Zhang Yufeng; Mei Jianqin
2012-01-01
A 3 × 3 matrix Lie algebra is first introduced, its subalgebras and the generated Lie algebras are obtained, respectively. Applications of a few Lie subalgebras give rise to two integrable nonlinear hierarchies of evolution equations from their reductions we obtain the nonlinear Schrödinger equations, the mKdV equations, the Broer-Kaup (BK) equation and its generalized equation, etc. The linear and nonlinear integrable couplings of one integrable hierarchy presented in the paper are worked out by casting a 3 × 3 Lie subalgebra into a 2 × 2 matrix Lie algebra. Finally, we discuss the elliptic variable solutions of a generalized BK equation. (general)
3D cancer cell migration in a confined matrix
Alobaidi, Amani; Sun, Bo
Cancer cell migration is widely studied in 2D motion, which does not mimic the invasion processes in vivo. More recently, 3D cell migration studies have been performed. The ability of cancer cells to migrate within the extracellular matrix depends on the physical and biochemical features of the extracellular matrix. We present a model of cell motility in confined matrix geometry. The aim of the study is to study cancer migration in collagen matrix, as a soft tissue, to investigate their motility within the confined and surrounding collagen environment. Different collagen concentrations have been used to show the ability of these cancer cells to move through such a complex structure by measuring Cancer cell migration velocity as well as the displacement. Graduate student physics department.
Study of the mechanisms of matrix assisted laser desorption / ionization
International Nuclear Information System (INIS)
Manuelli, Pascal
1995-01-01
This research thesis aims at a better knowledge of some aspects of a complex mechanism: the matrix-assisted laser desorption/ionization (MALDI). The author first proposes a comparative analysis of results obtained by time-of-flight (TOF) mass spectrometry and by Fourier transform mass spectrometry. He reports the study of the matrix role (notably a polymeric matrix) as a matter submitted to laser desorption. In this respect, the influence of the incident wavelength has been studied. The author also reports a comparative of ions produced by matrix laser desorption (study performed by Fourier transform mass spectrometry) and of neutral molecules (study performed by flash pyrolysis coupled with gas chromatography and with mass spectrometry). Finally, results obtained on derivatives and complexes based on beta-cyclodextrins highlight benefits as well as limitations of this technique [fr
Creation of an acellular vaginal matrix for potential vaginal augmentation and cloacal repair.
Greco, K V; Jones, L G; Obiri-Yeboa, I; Ansari, T
2018-05-21
our aim was to use porcine vagina to create a vaginal matrix and test its cellular biocompatibility. vagina was harvested from pigs and de-cellularised (DC) using a combination of detergents (Triton x-100 and sodium deoxycholate) and enzymes (DNAse/RNAse). the presence of cellular material, collagen structural integrity and basement membrane proteins were assessed histologically. To address cytocompatibility, porcine adipose derived-mesenchymal stem cells (AD-MSC) were harvested from abdominal fat together with vaginal epithelial cells (VEC) and seeded onto the mucosal aspect of the vaginal scaffold. Both cells populations were seeded individually and assessed histologically at days 3 and 10. MAIN OUTCOMES/RESULTS: the combination of enzymes and detergents resulted in a totally acellular matrix with very low DNA amount (control= 97.5ng/μl ± 10.8 vs DC= 40.1 ng/μl ±0.33 p=0.02). The extra cellular matrix (ECM) showed retention of collagen fibres and elastin and a 50% retention in glycosaminoglycan content; (control= 1.18μg/mg ± 0.28 DC = 1.35μg/mg ± 0.1 p=0.03) and an intact basement membrane (positive for both laminin and collagen IV). Seeded scaffolds showed cell attachment with both AD-MSC and VEC at days 3 and 10. it is possible to generate an acellular porcine vaginal matrix capable of supporting cells to reconstruct the vagina for future pre-clinical testing, and holds promise for creating clinically relevant sized tissue for human application. Copyright © 2018. Published by Elsevier Inc.
International Nuclear Information System (INIS)
Martensson, P.; Cronstrand, P.
2013-01-01
Cement based materials are often used as a solidification matrix for wet radioactive waste from nuclear power plants such as ion exchange resins, sludge and evaporator concentrates. The mechanical and chemical properties of the cement-waste matrix are affected by the type and the concentration of the waste. For this reason the recipe used in the solidification process has to be carefully adjusted to respond to the variations of the waste. At the Ringhals Nuclear Power Plant (RNPP) an evaporator was to be taken into operation during the mid 2005. As a result of this process an evaporator concentrate containing boric acid was expected. The aims of the present study were to develop a recipe for the solidification of artificial evaporator concentrates, (AEC), containing H 3 BO 3 and measure the compressive strength of the waste/cement matrix over a period of 4 years. The confirmation of the previously reported retarding properties of H 3 BO 3 and the studies of AEC without H 3 BO 3 were also included as a part of this work. Finally, thermodynamic calculations were used as a tool in order to predict the evolution of the mineralogy and integrity for the different cement-waste specimens over very long periods of time, i.e. up to about 100 000 years. The most important finding was that when an optimized waste/cement matrix recipe was used the compressive strength increased during the entire 4 year period and no signs of degradation were noticed. It was also found that the long-term performance of the waste matrices is to a large extent site-specific. In general, the composition of the infiltrating water is more influential than the waste matrices, both on the degradation of the waste matrices itself as well as on the engineered barriers. (author)
IL-1ß and BMPs - Interactive players of cartilage matrix degradation and regeneration
Directory of Open Access Journals (Sweden)
T Aigner
2006-10-01
Full Text Available Intact human adult articular cartilage is central for the functioning of the articulating joints. This largely depends on the integrity of its extracellular matrix, given the high loading forces during movements in particular in the weight-bearing joints. Unlike the first impression of a more or less static tissue, articular cartilage shows - albeit in the adult organism a slow - tissue turnover. Thus, one of the most important questions in osteoarthritis research is to understand the balance of catabolic and anabolic factors in articular cartilage as this is the key to understand the biology of cartilage maintenance and degeneration. Anabolic and catabolic pathways are very much intermingled in articular cartilage. The balance between anabolism and catabolism is titrated on numerous levels, starting from the mediator-synthesizing cells which express either catabolic or anabolic factors. Also, on the level of the effector cells (i.e. chondrocytes anabolic and catabolic gene expression compete for a balance of matrix homeostasis, namely the synthesis of matrix components and the expression and activation of matrix-degrading proteases. Also, there are multiple layers of intracellular cross-talks in between the anabolic and catabolic signalling pathways. Maybe the most important lesson from this overview is the notion that the anabolic-catabolic balance as such counts and not so much sufficient net anabolism or limited catabolism alone. Thus, it might be neither the aim of osteoarthritis therapy to foster anabolism nor to knock down catabolism, but the balance of anabolic-catabolic activities as a total might need proper titration and balancing.
EISPACK, Subroutines for Eigenvalues, Eigenvectors, Matrix Operations
International Nuclear Information System (INIS)
Garbow, Burton S.; Cline, A.K.; Meyering, J.
1993-01-01
1 - Description of problem or function: EISPACK3 is a collection of 75 FORTRAN subroutines, both single- and double-precision, that compute the eigenvalues and eigenvectors of nine classes of matrices. The package can determine the Eigen-system of complex general, complex Hermitian, real general, real symmetric, real symmetric band, real symmetric tridiagonal, special real tridiagonal, generalized real, and generalized real symmetric matrices. In addition, there are two routines which use the singular value decomposition to solve certain least squares problem. The individual subroutines are - Identification/Description: BAKVEC: Back transform vectors of matrix formed by FIGI; BALANC: Balance a real general matrix; BALBAK: Back transform vectors of matrix formed by BALANC; BANDR: Reduce sym. band matrix to sym. tridiag. matrix; BANDV: Find some vectors of sym. band matrix; BISECT: Find some values of sym. tridiag. matrix; BQR: Find some values of sym. band matrix; CBABK2: Back transform vectors of matrix formed by CBAL; CBAL: Balance a complex general matrix; CDIV: Perform division of two complex quantities; CG: Driver subroutine for a complex general matrix; CH: Driver subroutine for a complex Hermitian matrix; CINVIT: Find some vectors of complex Hess. matrix; COMBAK: Back transform vectors of matrix formed by COMHES; COMHES: Reduce complex matrix to complex Hess. (elementary); COMLR: Find all values of complex Hess. matrix (LR); COMLR2: Find all values/vectors of cmplx Hess. matrix (LR); CCMQR: Find all values of complex Hessenberg matrix (QR); COMQR2: Find all values/vectors of cmplx Hess. matrix (QR); CORTB: Back transform vectors of matrix formed by CORTH; CORTH: Reduce complex matrix to complex Hess. (unitary); CSROOT: Find square root of complex quantity; ELMBAK: Back transform vectors of matrix formed by ELMHES; ELMHES: Reduce real matrix to real Hess. (elementary); ELTRAN: Accumulate transformations from ELMHES (for HQR2); EPSLON: Estimate unit roundoff
Program package for calculating matrix elements of two-cluster structures in nuclei
International Nuclear Information System (INIS)
Krivec, R.; Mihailovic, M.V.; Kernforschungszentrum Karlsruhe G.m.b.H.
1982-01-01
Matrix elements of operators between Slater determinants of two-cluster structures must be expanded into partial waves for the purpose of angular momentum projection. The expansion coefficients contain integrals over the spherical angles theta and phi. (orig.)
Multidimensionality evaluation of supply chain management integration
Directory of Open Access Journals (Sweden)
Fernanda Paes Arantes
2018-03-01
Full Text Available Integration is constantly reported in the literature as an essential feature of SCM. However, it is as difficult to define as to operationalize it, resulting in a lack of information on how to increase the level of integration among members. Thus, this research aims to evaluate the dimensionality of SCI, to check alignment with the features identified in the literature using multivariate statistical analysis. The methodology used was based on a questionnaire to assess the level of companies integration with suppliers of its supply chain. This instrument consisted of 21 items, with response options: yes, no or not applicable. The questions focused on evaluating the integration with suppliers, so each company consulted could answer a questionnaire for each supplier, since the intensity of relationships varies. Thus, 41 companies participated in the survey, resulting in 205 responses. Full-information item factor analysis and principal component analysis on the correlation matrix tetrachoric were used for the instrument dimensionality analysis. They are appropriate procedures for analysis of dichotomous variables. The results of this analysis enabled grouping the questionnaire items in the following underlying factors: trust, information sharing, partnership, collaboration or cooperation, and coordination. The identification of such factors such as dimensions of SCI enables greater understanding on how to raise the level of integration among the members of a supply chain.
Quasi-exact evaluation of time domain MFIE MOT matrix elements
Shi, Yifei
2013-07-01
A previously proposed quasi-exact scheme for evaluating matrix elements resulting from the marching-on-in-time (MOT) discretization of the time domain electric field integral equation (EFIE) is extended to matrix entries resulting from the discretization of its magnetic field integral equation (MFIE) counterpart. Numerical results demonstrate the accuracy of the scheme as well as the late-time stability of the resulting MOT-MFIE solver. © 2013 IEEE.
Quasi-exact evaluation of time domain MFIE MOT matrix elements
Shi, Yifei; Bagci, Hakan; Shanker, Balasubramaniam; Lu, Mingyu; Michielssen, Eric
2013-01-01
A previously proposed quasi-exact scheme for evaluating matrix elements resulting from the marching-on-in-time (MOT) discretization of the time domain electric field integral equation (EFIE) is extended to matrix entries resulting from the discretization of its magnetic field integral equation (MFIE) counterpart. Numerical results demonstrate the accuracy of the scheme as well as the late-time stability of the resulting MOT-MFIE solver. © 2013 IEEE.
r-Matrix Structure for a Restricted Flow with Bargmann Constraint
International Nuclear Information System (INIS)
Chen Jinbing; Geng Xianguo
2005-01-01
This paper deals with the integrability of a finite-dimensional Hamiltonian system linked with the generalized coupled KdV hierarchy. For this purpose the associated Lax representation is presented after an elementary calculation. It is shown that the Lax representation enjoys a dynamical r-matrix formula instead of a classical one in the Poisson bracket on R 2N . Consequently the resulting system is proved to be completely integrable in view of its r-matrix structure.
A survey of matrix theory and matrix inequalities
Marcus, Marvin
2010-01-01
Written for advanced undergraduate students, this highly regarded book presents an enormous amount of information in a concise and accessible format. Beginning with the assumption that the reader has never seen a matrix before, the authors go on to provide a survey of a substantial part of the field, including many areas of modern research interest.Part One of the book covers not only the standard ideas of matrix theory, but ones, as the authors state, ""that reflect our own prejudices,"" among them Kronecker products, compound and induced matrices, quadratic relations, permanents, incidence
Octonionic matrix representation and electromagnetism
Energy Technology Data Exchange (ETDEWEB)
Chanyal, B. C. [Kumaun University, S. S. J. Campus, Almora (India)
2014-12-15
Keeping in mind the important role of octonion algebra, we have obtained the electromagnetic field equations of dyons with an octonionic 8 x 8 matrix representation. In this paper, we consider the eight - dimensional octonionic space as a combination of two (external and internal) four-dimensional spaces for the existence of magnetic monopoles (dyons) in a higher-dimensional formalism. As such, we describe the octonion wave equations in terms of eight components from the 8 x 8 matrix representation. The octonion forms of the generalized potential, fields and current source of dyons in terms of 8 x 8 matrix are discussed in a consistent manner. Thus, we have obtained the generalized Dirac-Maxwell equations of dyons from an 8x8 matrix representation of the octonion wave equations in a compact and consistent manner. The generalized Dirac-Maxwell equations are fully symmetric Maxwell equations and allow for the possibility of magnetic charges and currents, analogous to electric charges and currents. Accordingly, we have obtained the octonionic Dirac wave equations in an external field from the matrix representation of the octonion-valued potentials of dyons.
Directory of Open Access Journals (Sweden)
Delmo Alves Moura
2011-06-01
Full Text Available This study describes aspects related to coastal shipping in Brazil and its main actors and intermodal factors (road, rail, fluvial transportation etc. which corroborate to the increase of logistics competitiveness and efficiency of transportation in a large country like Brazil. The purpose of the study is bibliographic research on the topic, analyzing it inside the Brazilian scenario and also how it has been implemented in some countries. The objective of the study is also analyzing legislation which defines parameters to coastal shipping. This fact interferes directly with the logistics system and its intermodal aspects. If Brazil intends to reduce its logistics costs, coastal shipping should be an effective way to contribute to the Brazilian matrix of transport. Coastal shipping is supposed to bring competitive advantage and reduction of logistic costs. The conclusion is that integration is essential among the systems of domestic transportation and coastal shipping with its outstanding role in this environment, can contribute substantially to the Brazilian maritime industry.
Development of AIM for analysing policy options to reduce greenhouse gas emissions
International Nuclear Information System (INIS)
Kainuma, M.; Morita, T.; Matsuoka, Y.
1999-01-01
AIM (Asian-Pacific Integrated Model) has been developed for predicting greenhouse gas emissions and evaluating policy measures to reduce them. Two socio-economic scenarios were assumed and CO 2 emissions were predicted based on these scenarios and policy intervention assumptions. It is found that mitigating CO 2 emissions without scaling back productive activities or standards of living in Japan is possible. However, if one relies on the market mechanism alone, it cannot be done. The analysis has shown that it is essential to introduce new policies and measures such as carbon tax and subsidies. (author)
International Nuclear Information System (INIS)
Heggarty, J.W.
1999-06-01
For almost thirty years, sequential R-matrix computation has been used by atomic physics research groups, from around the world, to model collision phenomena involving the scattering of electrons or positrons with atomic or molecular targets. As considerable progress has been made in the understanding of fundamental scattering processes, new data, obtained from more complex calculations, is of current interest to experimentalists. Performing such calculations, however, places considerable demands on the computational resources to be provided by the target machine, in terms of both processor speed and memory requirement. Indeed, in some instances the computational requirements are so great that the proposed R-matrix calculations are intractable, even when utilising contemporary classic supercomputers. Historically, increases in the computational requirements of R-matrix computation were accommodated by porting the problem codes to a more powerful classic supercomputer. Although this approach has been successful in the past, it is no longer considered to be a satisfactory solution due to the limitations of current (and future) Von Neumann machines. As a consequence, there has been considerable interest in the high performance multicomputers, that have emerged over the last decade which appear to offer the computational resources required by contemporary R-matrix research. Unfortunately, developing codes for these machines is not as simple a task as it was to develop codes for successive classic supercomputers. The difficulty arises from the considerable differences in the computing models that exist between the two types of machine and results in the programming of multicomputers to be widely acknowledged as a difficult, time consuming and error-prone task. Nevertheless, unless parallel R-matrix computation is realised, important theoretical and experimental atomic physics research will continue to be hindered. This thesis describes work that was undertaken in
Numerical methods in matrix computations
Björck, Åke
2015-01-01
Matrix algorithms are at the core of scientific computing and are indispensable tools in most applications in engineering. This book offers a comprehensive and up-to-date treatment of modern methods in matrix computation. It uses a unified approach to direct and iterative methods for linear systems, least squares and eigenvalue problems. A thorough analysis of the stability, accuracy, and complexity of the treated methods is given. Numerical Methods in Matrix Computations is suitable for use in courses on scientific computing and applied technical areas at advanced undergraduate and graduate level. A large bibliography is provided, which includes both historical and review papers as well as recent research papers. This makes the book useful also as a reference and guide to further study and research work. Åke Björck is a professor emeritus at the Department of Mathematics, Linköping University. He is a Fellow of the Society of Industrial and Applied Mathematics.
Integral or integrated marketing
Directory of Open Access Journals (Sweden)
Davčik Nebojša
2006-01-01
Full Text Available Marketing theorists and experts try to develop business efficient organization and to get marketing performance at higher, business integrated level since its earliest beginnings. The core issue in this paperwork is the dialectic and practical approach dilemma should we develop integrated or integral marketing approach in the organization. The presented company cases as well as dialectic and functional explanations of this dilemma clearly shows that integrated marketing is narrower approach than integral marketing if we take as focal point new, unique and completed entity. In the integration the essence is in getting different parts together, which do not have to make necessary the new entity. The key elements in the definition of the integral marketing are necessity and holistic, e.g. necessity to develop new, holistic entity.
A new operational matrix of fractional order integration for the ...
Indian Academy of Sciences (India)
M H HEYDARI
1Department of Mathematics, Shiraz University of Technology, Shiraz, Iran. 2Center of ... published online 24 April 2018. Abstract. ... a realistic modeling of a physical phenomenon having dependence not only at the time instant, but also on ...
A new operational matrix of fractional order integration for the ...
Indian Academy of Sciences (India)
49
1,2The Laboratory of Quantum Information Processing and Cryptography. ... the orthogonal functions may be widely classified into four families [41]. ... segmentations, time-frequency analysis and fast algorithms for easy implementation.
Towards Google matrix of brain
Energy Technology Data Exchange (ETDEWEB)
Shepelyansky, D.L., E-mail: dima@irsamc.ups-tlse.f [Laboratoire de Physique Theorique (IRSAMC), Universite de Toulouse, UPS, F-31062 Toulouse (France); LPT - IRSAMC, CNRS, F-31062 Toulouse (France); Zhirov, O.V. [Budker Institute of Nuclear Physics, 630090 Novosibirsk (Russian Federation)
2010-07-12
We apply the approach of the Google matrix, used in computer science and World Wide Web, to description of properties of neuronal networks. The Google matrix G is constructed on the basis of neuronal network of a brain model discussed in PNAS 105 (2008) 3593. We show that the spectrum of eigenvalues of G has a gapless structure with long living relaxation modes. The PageRank of the network becomes delocalized for certain values of the Google damping factor {alpha}. The properties of other eigenstates are also analyzed. We discuss further parallels and similarities between the World Wide Web and neuronal networks.
Towards Google matrix of brain
International Nuclear Information System (INIS)
Shepelyansky, D.L.; Zhirov, O.V.
2010-01-01
We apply the approach of the Google matrix, used in computer science and World Wide Web, to description of properties of neuronal networks. The Google matrix G is constructed on the basis of neuronal network of a brain model discussed in PNAS 105 (2008) 3593. We show that the spectrum of eigenvalues of G has a gapless structure with long living relaxation modes. The PageRank of the network becomes delocalized for certain values of the Google damping factor α. The properties of other eigenstates are also analyzed. We discuss further parallels and similarities between the World Wide Web and neuronal networks.
Inverse Interval Matrix: A Survey
Czech Academy of Sciences Publication Activity Database
Rohn, Jiří; Farhadsefat, R.
2011-01-01
Roč. 22, - (2011), s. 704-719 E-ISSN 1081-3810 R&D Projects: GA ČR GA201/09/1957; GA ČR GC201/08/J020 Institutional research plan: CEZ:AV0Z10300504 Keywords : interval matrix * inverse interval matrix * NP-hardness * enclosure * unit midpoint * inverse sign stability * nonnegative invertibility * absolute value equation * algorithm Subject RIV: BA - General Mathematics Impact factor: 0.808, year: 2010 http://www.math.technion.ac.il/iic/ ela / ela -articles/articles/vol22_pp704-719.pdf
Symmetries and Interactions in Matrix String Theory
Hacquebord, F.H.
1999-01-01
This PhD-thesis reviews matrix string theory and recent developments therein. The emphasis is put on symmetries, interactions and scattering processes in the matrix model. We start with an introduction to matrix string theory and a review of the orbifold model that flows out of matrix string theory
Time integration of tensor trains
Lubich, Christian; Oseledets, Ivan; Vandereycken, Bart
2014-01-01
A robust and efficient time integrator for dynamical tensor approximation in the tensor train or matrix product state format is presented. The method is based on splitting the projector onto the tangent space of the tensor manifold. The algorithm can be used for updating time-dependent tensors in the given data-sparse tensor train / matrix product state format and for computing an approximate solution to high-dimensional tensor differential equations within this data-sparse format. The formul...
Steffensen's integral inequality for conformable fractional integrals
Directory of Open Access Journals (Sweden)
Mehmet Zeki Sarikaya
2017-09-01
Full Text Available The aim of this paper is to establish some Steffensen’s type inequalities for conformable fractional integral. The results presented here would provide generalizations of those given in earlier works.
Matrix metalloproteinase-8 overexpression prevents proper tissue repair
DEFF Research Database (Denmark)
Danielsen, Patricia L; Holst, Anders V; Maltesen, Henrik R
2011-01-01
The collagenolytic matrix metalloproteinase-8 (MMP-8) is essential for normal tissue repair but is often overexpressed in wounds with disrupted healing. Our aim was to study the impact of a local excess of this neutrophil-derived proteinase on wound healing using recombinant adenovirus...
Suen, J P; Su, W C
2010-09-01
This research proposes a simplified method for estimating the mesohabitat composition that would favour members of a given set of aquatic species. The simulated composition of four types of mesohabitat units (deep pool, shallow pool, deep riffle and shallow riffle) could guide the design of in-stream structures in creating pool-riffle systems with ecological reference. Fish community data and an autecology matrix are used to support the development of a stream mesohabitat simulation based on regression models for reaches in mid to upper-order streams. The fish community-mesohabitat model results constitute a reference condition that can be used to guide stream restoration and ecological engineering decisions aimed at maintaining the natural ecological integrity and diversity of rivers. © 2010 The Authors. Journal compilation © 2010 The Fisheries Society of the British Isles.
A non-equilibrium thermodynamic model for tumor extracellular matrix with enzymatic degradation
Xue, Shi-Lei; Li, Bo; Feng, Xi-Qiao; Gao, Huajian
2017-07-01
The extracellular matrix (ECM) of a solid tumor not only affords scaffolding to support tumor architecture and integrity but also plays an essential role in tumor growth, invasion, metastasis, and therapeutics. In this paper, a non-equilibrium thermodynamic theory is established to study the chemo-mechanical behaviors of tumor ECM, which is modeled as a poroelastic polyelectrolyte consisting of a collagen network and proteoglycans. By using the principle of maximum energy dissipation rate, we deduce a set of governing equations for drug transport and mechanosensitive enzymatic degradation in ECM. The results reveal that osmosis is primarily responsible for the compression resistance of ECM. It is suggested that a well-designed ECM degradation can effectively modify the tumor microenvironment for improved efficiency of cancer therapy. The theoretical predictions show a good agreement with relevant experimental observations. This study aimed to deepen our understanding of tumor ECM may be conducive to novel anticancer strategies.
Study of the energy matrix of Minas Gerais considering the contribution of nuclear power plants
Energy Technology Data Exchange (ETDEWEB)
Filho, Wilson P.B., E-mail: wilson.filho@meioambiente.mg.gov.br [Fundaco Estadual do Meio Ambiente, Belo Horizonte, MG (Brazil); Costa, Antonella L.; Pinheiro, Ricardo B.; Fortini, Angela, E-mail: antonella@nuclear.ufmg.br, E-mail: rbrantp@gmail.com, E-mail: fortini@nuclear.ufmg.br [Universidade Federal de Minas Gerais (UFMG), Belo horizonte, MG (Brazil). Departamento de Engenharia Nuclear
2015-07-01
The integrated energy planning is a very important tool for long-term study, projections and reviews of the energy mix of a country or region. By dealing with energy supply and demand projections is therefore related to the needs of society and its development index within a context of sustainability. The aim of this study is to provide information about the Minas Gerais electric matrix and propose solutions for the need of future energy import. In this way, it is proposed a possible deployment of nuclear power plants, in parallel with wind and solar energy, for the necessary energy expansion in the face of population growth framework and energy use in Minas Gerais. Thus, the study tends to contribute to decision-making related to public policies. (author)
Study of the energy matrix of Minas Gerais considering the contribution of nuclear power plants
International Nuclear Information System (INIS)
Filho, Wilson P.B.; Costa, Antonella L.; Pinheiro, Ricardo B.; Fortini, Angela
2015-01-01
The integrated energy planning is a very important tool for long-term study, projections and reviews of the energy mix of a country or region. By dealing with energy supply and demand projections is therefore related to the needs of society and its development index within a context of sustainability. The aim of this study is to provide information about the Minas Gerais electric matrix and propose solutions for the need of future energy import. In this way, it is proposed a possible deployment of nuclear power plants, in parallel with wind and solar energy, for the necessary energy expansion in the face of population growth framework and energy use in Minas Gerais. Thus, the study tends to contribute to decision-making related to public policies. (author)
Universality of correlation functions in random matrix models of QCD
International Nuclear Information System (INIS)
Jackson, A.D.; Sener, M.K.; Verbaarschot, J.J.M.
1997-01-01
We demonstrate the universality of the spectral correlation functions of a QCD inspired random matrix model that consists of a random part having the chiral structure of the QCD Dirac operator and a deterministic part which describes a schematic temperature dependence. We calculate the correlation functions analytically using the technique of Itzykson-Zuber integrals for arbitrary complex supermatrices. An alternative exact calculation for arbitrary matrix size is given for the special case of zero temperature, and we reproduce the well-known Laguerre kernel. At finite temperature, the microscopic limit of the correlation functions are calculated in the saddle-point approximation. The main result of this paper is that the microscopic universality of correlation functions is maintained even though unitary invariance is broken by the addition of a deterministic matrix to the ensemble. (orig.)
Characterization of membrane association of Rinderpest virus matrix protein
International Nuclear Information System (INIS)
Subhashri, R.; Shaila, M.S.
2007-01-01
Paramyxovirus matrix protein is believed to play a crucial role in the assembly and maturation of the virus particle by bringing the major viral components together at the budding site in the host cell. The membrane association capability of many enveloped virus matrix proteins has been characterized to be their intrinsic property. In this work, we have characterized the membrane association of Rinderpest virus matrix (M) protein. The M protein of Rinderpest virus when expressed in the absence of other viral proteins is present both in the cytoplasm and plasma membrane. When expressed as GFP fusion protein, the M protein gets localized into plasma membrane protrusions. High salt and alkaline conditions resulted in partial dissociation of M protein from cell membrane. Thus, M protein behaves like an integral membrane protein although its primary structure suggests it to be a peripheral membrane protein
Matrix model as a mirror of Chern-Simons theory
International Nuclear Information System (INIS)
Aganagic, Mina; Klemm, Albrecht; Marino, Marcos; Vafa, Cumrun
2004-01-01
Using mirror symmetry, we show that Chern-Simons theory on certain manifolds such as lens spaces reduces to a novel class of Hermitian matrix models, where the measure is that of unitary matrix models. We show that this agrees with the more conventional canonical quantization of Chern-Simons theory. Moreover, large N dualities in this context lead to computation of all genus A-model topological amplitudes on toric Calabi-Yau manifolds in terms of matrix integrals. In the context of type IIA superstring compactifications on these Calabi-Yau manifolds with wrapped D6 branes (which are dual to M-theory on G2 manifolds) this leads to engineering and solving F-terms for N=1 supersymmetric gauge theories with superpotentials involving certain multi-trace operators. (author)
Orbifolds and Exact Solutions of Strongly-Coupled Matrix Models
Córdova, Clay; Heidenreich, Ben; Popolitov, Alexandr; Shakirov, Shamil
2018-02-01
We find an exact solution to strongly-coupled matrix models with a single-trace monomial potential. Our solution yields closed form expressions for the partition function as well as averages of Schur functions. The results are fully factorized into a product of terms linear in the rank of the matrix and the parameters of the model. We extend our formulas to include both logarithmic and finite-difference deformations, thereby generalizing the celebrated Selberg and Kadell integrals. We conjecture a formula for correlators of two Schur functions in these models, and explain how our results follow from a general orbifold-like procedure that can be applied to any one-matrix model with a single-trace potential.
Modeling food matrix effects on chemical reactivity: Challenges and perspectives.
Capuano, Edoardo; Oliviero, Teresa; van Boekel, Martinus A J S
2017-06-29
The same chemical reaction may be different in terms of its position of the equilibrium (i.e., thermodynamics) and its kinetics when studied in different foods. The diversity in the chemical composition of food and in its structural organization at macro-, meso-, and microscopic levels, that is, the food matrix, is responsible for this difference. In this viewpoint paper, the multiple, and interconnected ways the food matrix can affect chemical reactivity are summarized. Moreover, mechanistic and empirical approaches to explain and predict the effect of food matrix on chemical reactivity are described. Mechanistic models aim to quantify the effect of food matrix based on a detailed understanding of the chemical and physical phenomena occurring in food. Their applicability is limited at the moment to very simple food systems. Empirical modeling based on machine learning combined with data-mining techniques may represent an alternative, useful option to predict the effect of the food matrix on chemical reactivity and to identify chemical and physical properties to be further tested. In such a way the mechanistic understanding of the effect of the food matrix on chemical reactions can be improved.
Integral consideration of integrated management systems
International Nuclear Information System (INIS)
Frauenknecht, Stefan; Schmitz, Hans
2010-01-01
Aim of the project for the NPPs Kruemmel and Brunsbuettel (Vattenfall) is the integral view of the business process as basis for the implementation and operation of management systems in the domains quality, safety and environment. The authors describe the integral view of the business processes in the frame of integrated management systems with the focus nuclear safety, lessons learned in the past, the concept of a process-based controlling system and experiences from the practical realization.
Parallel Sparse Matrix - Vector Product
DEFF Research Database (Denmark)
Alexandersen, Joe; Lazarov, Boyan Stefanov; Dammann, Bernd
This technical report contains a case study of a sparse matrix-vector product routine, implemented for parallel execution on a compute cluster with both pure MPI and hybrid MPI-OpenMP solutions. C++ classes for sparse data types were developed and the report shows how these class can be used...
Unravelling the nuclear matrix proteome
DEFF Research Database (Denmark)
Albrethsen, Jakob; Knol, Jaco C; Jimenez, Connie R
2009-01-01
The nuclear matrix (NM) model posits the presence of a protein/RNA scaffold that spans the mammalian nucleus. The NM proteins are involved in basic nuclear function and are a promising source of protein biomarkers for cancer. Importantly, the NM proteome is operationally defined as the proteins...
Amorphous metal matrix composite ribbons
International Nuclear Information System (INIS)
Barczy, P.; Szigeti, F.
1998-01-01
Composite ribbons with amorphous matrix and ceramic (SiC, WC, MoB) particles were produced by modified planar melt flow casting methods. Weldability, abrasive wear and wood sanding examinations were carried out in order to find optimal material and technology for elevated wear resistance and sanding durability. The correlation between structure and composite properties is discussed. (author)
Hyper-systolic matrix multiplication
Lippert, Th.; Petkov, N.; Palazzari, P.; Schilling, K.
A novel parallel algorithm for matrix multiplication is presented. It is based on a 1-D hyper-systolic processor abstraction. The procedure can be implemented on all types of parallel systems. (C) 2001 Elsevier Science B,V. All rights reserved.
Matrix Metalloproteinases in Myasthenia Gravis
Helgeland, G.; Petzold, A.F.S.; Luckman, S.P.; Gilhus, N.E.; Plant, G.T.; Romi, F.R.
2011-01-01
Introduction: Myasthenia gravis (MG) is an autoimmune disease with weakness in striated musculature due to anti-acetylcholine receptor (AChR) antibodies or muscle specific kinase at the neuromuscular junction. A subgroup of patients has periocular symptoms only; ocular MG (OMG). Matrix
The COMPADRE Plant Matrix Database
DEFF Research Database (Denmark)
2014-01-01
COMPADRE contains demographic information on hundreds of plant species. The data in COMPADRE are in the form of matrix population models and our goal is to make these publicly available to facilitate their use for research and teaching purposes. COMPADRE is an open-access database. We only request...
Czech Academy of Sciences Publication Activity Database
Rohn, Jiří
2013-01-01
Roč. 26, 15 December (2013), s. 836-841 ISSN 1537-9582 Institutional support: RVO:67985807 Keywords : two-matrix alternative * solution * algorithm Subject RIV: BA - General Mathematics Impact factor: 0.514, year: 2013 http://www.math.technion.ac.il/iic/ ela / ela -articles/articles/vol26_pp836-841.pdf
Regularization in Matrix Relevance Learning
Schneider, Petra; Bunte, Kerstin; Stiekema, Han; Hammer, Barbara; Villmann, Thomas; Biehl, Michael
A In this paper, we present a regularization technique to extend recently proposed matrix learning schemes in learning vector quantization (LVQ). These learning algorithms extend the concept of adaptive distance measures in LVQ to the use of relevance matrices. In general, metric learning can
International Nuclear Information System (INIS)
Bowles, K.J.
1985-01-01
A study was conducted to relate the impact resistance of graphite fiber reinforced composites with matrix properties through gaining an understanding of the basic mechanics involved in the deformation and fracture process, and the effect of the polymer matrix structure on these mechanisms. It was found that the resin matrix structure influences the composite impact resistance in at least two ways. The integration of flexibilizers into the polymer chain structure tends to reduce the T/sub G/ and the mechanical properties of the polymer. The reduction in the mechanical properties of the matrix does not enhance the composite impact resistance because it allows matrix controlled failure to initiate impact damage. Linear polymers, which contain no active groups for cross-linking, do not toughen composites because the fiber-matrix interfacial bond is not of sufficient strength to prevent interfacial failure from occurring. Toughness must be built into the basic polymer backbone and cross-linking structure
Integrated care: a comprehensive bibliometric analysis and literature review
Directory of Open Access Journals (Sweden)
Xiaowei Sun
2014-06-01
Full Text Available Introduction: Integrated care could not only fix up fragmented health care but also improve the continuity of care and the quality of life. Despite the volume and variety of publications, little is known about how ‘integrated care’ has developed. There is a need for a systematic bibliometric analysis on studying the important features of the integrated care literature.Aim: To investigate the growth pattern, core journals and jurisdictions and identify the key research domains of integrated care.Methods: We searched Medline/PubMed using the search strategy ‘(delivery of health care, integrated [MeSH Terms] OR integrated care [Title/Abstract]’ without time and language limits. Second, we extracted the publishing year, journals, jurisdictions and keywords of the retrieved articles. Finally, descriptive statistical analysis by the Bibliographic Item Co-occurrence Matrix Builder and hierarchical clustering by SPSS were used.Results: As many as 9090 articles were retrieved. Results included: (1 the cumulative numbers of the publications on integrated care rose perpendicularly after 1993; (2 all documents were recorded by 1646 kinds of journals. There were 28 core journals; (3 the USA is the predominant publishing country; and (4 there are six key domains including: the definition/models of integrated care, interdisciplinary patient care team, disease management for chronically ill patients, types of health care organizations and policy, information system integration and legislation/jurisprudence.Discussion and conclusion: Integrated care literature has been most evident in developed countries. International Journal of Integrated Care is highly recommended in this research area. The bibliometric analysis and identification of publication hotspots provides researchers and practitioners with core target journals, as well as an overview of the field for further research in integrated care.
Rotation of hard particles in a soft matrix
Yang, Weizhu; Liu, Qingchang; Yue, Zhufeng; Li, Xiaodong; Xu, Baoxing
Soft-hard materials integration is ubiquitous in biological materials and structures in nature and has also attracted growing attention in the bio-inspired design of advanced functional materials, structures and devices. Due to the distinct difference in their mechanical properties, the rotation of hard phases in soft matrixes upon deformation has been acknowledged, yet is lack of theory in mechanics. In this work, we propose a theoretical mechanics framework that can describe the rotation of hard particles in a soft matrix. The rotation of multiple arbitrarily shaped, located and oriented particles with perfectly bonded interfaces in an elastic soft matrix subjected to a far-field tensile loading is established and analytical solutions are derived by using complex potentials and conformal mapping methods. Strong couplings and competitions of the rotation of hard particles among each other are discussed by investigating numbers, relative locations and orientations of particles in the matrix at different loading directions. Extensive finite element analyses are performed to validate theoretical solutions and good agreement of both rotation and stress field between them are achieved. Possible extensions of the present theory to non-rigid particles, viscoelastic matrix and imperfect bonding are also discussed. Finally, by taking advantage of the rotation of hard particles, we exemplify an application in a conceptual design of soft-hard material integrated phononic crystal and demonstrate that phononic band gaps can be successfully tuned with a high accuracy through the mechanical tension-induced rotation of hard particles. The present theory established herein is expected to be of immediate interests to the design of soft-hard materials integration based functional materials, structures and devices with tunable performance via mechanical rotation of hard phases.
PLA and two components silicon rubber blends aiming for frozen foods packaging applications
Directory of Open Access Journals (Sweden)
Utai Meekum
2018-03-01
Full Text Available Designing of PLA and two components silicone rubber blends was studies. Frozen food packaging application is the main ultimate aim. The statistical method using 23 DOE was conducted. The standard testing methods, in particular impact testing at sub-zero temperature, were performed. The preliminary blend formula comprised 1.0 phr of silane and polyester polyols, respectively, was initially resolved. Then, the optimize the silicone portion in the blends was determined. Blending formula using 8.0 phr of silicone with respect to PLA matrix gave rise to the overall satisfactory properties. 3. TETA was used as the silicone curing agent and reactively blended onto the ingredients. TETA at 0.4 phr, with respect to the silicone, enhanced the mechanical properties, especially flexibility and toughness, of the PLA/silicone blend. Exceeding the optimal TETA loading would cause the chain scission and also the dilution effects. Hence, marginal inferior properties of the blends were be experienced. The preliminary biodegradability investigation found that the PLA/silicone blend initially triggered at the second week. Its degradation rate was likely to be faster than neat PLA. Keywords: PLA/silicone blends, Mechanical properties, Sub-zero impact strength
PLA and two components silicon rubber blends aiming for frozen foods packaging applications
Meekum, Utai; Khiansanoi, Apichart
2018-03-01
Designing of PLA and two components silicone rubber blends was studies. Frozen food packaging application is the main ultimate aim. The statistical method using 23 DOE was conducted. The standard testing methods, in particular impact testing at sub-zero temperature, were performed. The preliminary blend formula comprised 1.0 phr of silane and polyester polyols, respectively, was initially resolved. Then, the optimize the silicone portion in the blends was determined. Blending formula using 8.0 phr of silicone with respect to PLA matrix gave rise to the overall satisfactory properties. 3. TETA was used as the silicone curing agent and reactively blended onto the ingredients. TETA at 0.4 phr, with respect to the silicone, enhanced the mechanical properties, especially flexibility and toughness, of the PLA/silicone blend. Exceeding the optimal TETA loading would cause the chain scission and also the dilution effects. Hence, marginal inferior properties of the blends were be experienced. The preliminary biodegradability investigation found that the PLA/silicone blend initially triggered at the second week. Its degradation rate was likely to be faster than neat PLA.
An integral transform related to quantization
International Nuclear Information System (INIS)
Daubechies, I.; Grossmann, A.
1978-08-01
The authors study in a coordinate-free way the integral transform relating a function on phase space to the matrix elements of the corresponding quantum mechanical operator between coherent states. The items discussed include: inversion (given by the same kernel), bounds, matrix elements between eigenstates of harmonic oscillators, and classical functions corresponding to permutation operators. (author)
Relativistic elliptic matrix tops and finite Fourier transformations
Zotov, A.
2017-10-01
We consider a family of classical elliptic integrable systems including (relativistic) tops and their matrix extensions of different types. These models can be obtained from the “off-shell” Lax pairs, which do not satisfy the Lax equations in general case but become true Lax pairs under various conditions (reductions). At the level of the off-shell Lax matrix, there is a natural symmetry between the spectral parameter z and relativistic parameter η. It is generated by the finite Fourier transformation, which we describe in detail. The symmetry allows one to consider z and η on an equal footing. Depending on the type of integrable reduction, any of the parameters can be chosen to be the spectral one. Then another one is the relativistic deformation parameter. As a by-product, we describe the model of N2 interacting GL(M) matrix tops and/or M2 interacting GL(N) matrix tops depending on a choice of the spectral parameter.
Hanle-Zeeman Scattering Matrix for Magnetic Dipole Transitions
Energy Technology Data Exchange (ETDEWEB)
Megha, A.; Sampoorna, M.; Nagendra, K. N.; Sankarasubramanian, K., E-mail: megha@iiap.res.in, E-mail: sampoorna@iiap.res.in, E-mail: knn@iiap.res.in, E-mail: sankar@iiap.res.in [Indian Institute of Astrophysics, Koramangala, Bengaluru 560 034 (India)
2017-06-01
The polarization of the light that is scattered by the coronal ions is influenced by the anisotropic illumination from the photosphere and the magnetic field structuring in the solar corona. The properties of the coronal magnetic fields can be well studied by understanding the polarization properties of coronal forbidden emission lines that arise from magnetic dipole ( M 1) transitions in the highly ionized atoms that are present in the corona. We present the classical scattering theory of the forbidden lines for a more general case of arbitrary-strength magnetic fields. We derive the scattering matrix for M 1 transitions using the classical magnetic dipole model of Casini and Lin and applying the scattering matrix approach of Stenflo. We consider a two-level atom model and neglect collisional effects. The scattering matrix so derived is used to study the Stokes profiles formed in coronal conditions in those regions where the radiative excitations dominate collisional excitations. To this end, we take into account the integration over a cone of an unpolarized radiation from the solar disk incident on the scattering atoms. Furthermore, we also integrate along the line of sight to calculate the emerging polarized line profiles. We consider radial and dipole magnetic field configurations and spherically symmetric density distributions. For our studies we adopt the atomic parameters corresponding to the [Fe xiii] 10747 Å coronal forbidden line. We also discuss the nature of the scattering matrix for M 1 transitions and compare it with that for the electric dipole ( E 1) transitions.
Minimal parameter solution of the orthogonal matrix differential equation
Bar-Itzhack, Itzhack Y.; Markley, F. Landis
1990-01-01
As demonstrated in this work, all orthogonal matrices solve a first order differential equation. The straightforward solution of this equation requires n sup 2 integrations to obtain the element of the nth order matrix. There are, however, only n(n-1)/2 independent parameters which determine an orthogonal matrix. The questions of choosing them, finding their differential equation and expressing the orthogonal matrix in terms of these parameters are considered. Several possibilities which are based on attitude determination in three dimensions are examined. It is shown that not all 3-D methods have useful extensions to higher dimensions. It is also shown why the rate of change of the matrix elements, which are the elements of the angular rate vector in 3-D, are the elements of a tensor of the second rank (dyadic) in spaces other than three dimensional. It is proven that the 3-D Gibbs vector (or Cayley Parameters) are extendable to other dimensions. An algorithm is developed emplying the resulting parameters, which are termed Extended Rodrigues Parameters, and numerical results are presented of the application of the algorithm to a fourth order matrix.
Matrix metalloproteinases in the brain and blood–brain barrier: Versatile breakers and makers
Rempe, Ralf G; Hartz, Anika MS
2016-01-01
Matrix metalloproteinases are versatile endopeptidases with many different functions in the body in health and disease. In the brain, matrix metalloproteinases are critical for tissue formation, neuronal network remodeling, and blood–brain barrier integrity. Many reviews have been published on matrix metalloproteinases before, most of which focus on the two best studied matrix metalloproteinases, the gelatinases MMP-2 and MMP-9, and their role in one or two diseases. In this review, we provide a broad overview of the role various matrix metalloproteinases play in brain disorders. We summarize and review current knowledge and understanding of matrix metalloproteinases in the brain and at the blood–brain barrier in neuroinflammation, multiple sclerosis, cerebral aneurysms, stroke, epilepsy, Alzheimer’s disease, Parkinson’s disease, and brain cancer. We discuss the detrimental effects matrix metalloproteinases can have in these conditions, contributing to blood–brain barrier leakage, neuroinflammation, neurotoxicity, demyelination, tumor angiogenesis, and cancer metastasis. We also discuss the beneficial role matrix metalloproteinases can play in neuroprotection and anti-inflammation. Finally, we address matrix metalloproteinases as potential therapeutic targets. Together, in this comprehensive review, we summarize current understanding and knowledge of matrix metalloproteinases in the brain and at the blood–brain barrier in brain disorders. PMID:27323783
Nuclear matrix - structure, function and pathogenesis.
Wasąg, Piotr; Lenartowski, Robert
2016-12-20
The nuclear matrix (NM), or nuclear skeleton, is the non-chromatin, ribonucleoproteinaceous framework that is resistant to high ionic strength buffers, nonionic detergents, and nucleolytic enzymes. The NM fulfills a structural role in eukaryotic cells and is responsible for maintaining the shape of the nucleus and the spatial organization of chromatin. Moreover, the NM participates in several cellular processes, such as DNA replication/repair, gene expression, RNA transport, cell signaling and differentiation, cell cycle regulation, apoptosis and carcinogenesis. Short nucleotide sequences called scaffold/matrix attachment regions (S/MAR) anchor the chromatin loops to the NM proteins (NMP). The NMP composition is dynamic and depends on the cell type and differentiation stage or metabolic activity. Alterations in the NMP composition affect anchoring of the S/MARs and thus alter gene expression. This review aims to systematize information about the skeletal structure of the nucleus, with particular emphasis on the organization of the NM and its role in selected cellular processes. We also discuss several diseases that are caused by aberrant NM structure or dysfunction of individual NM elements.
Omentin-1 prevents cartilage matrix destruction by regulating matrix metalloproteinases.
Li, Zhigang; Liu, Baoyi; Zhao, Dewei; Wang, BenJie; Liu, Yupeng; Zhang, Yao; Li, Borui; Tian, Fengde
2017-08-01
Matrix metalloproteinases (MMPs) play a crucial role in the degradation of the extracellular matrix and pathological progression of osteoarthritis (OA). Omentin-1 is a newly identified anti-inflammatory adipokine. Little information regarding the protective effects of omentin-1 in OA has been reported before. In the current study, our results indicated that omentin-1 suppressed expression of MMP-1, MMP-3, and MMP-13 induced by the proinflammatory cytokine interleukin-1β (IL-1β) at both the mRNA and protein levels in human chondrocytes. Importantly, administration of omentin-1 abolished IL-1β-induced degradation of type II collagen (Col II) and aggrecan, the two major extracellular matrix components in articular cartilage, in a dose-dependent manner. Mechanistically, omentin-1 ameliorated the expression of interferon regulatory factor 1 (IRF-1) by blocking the JAK-2/STAT3 pathway. Our results indicate that omentin-1 may have a potential chondroprotective therapeutic capacity. Copyright © 2017 Elsevier Masson SAS. All rights reserved.
Gabriela Mistral, in a Maternal-Matrix-Material Language
Directory of Open Access Journals (Sweden)
María Binetti
2017-10-01
Full Text Available For some decades, feminist thinkers such as Luce Irigaray, Luisa Muraro and Rosi Braidotti —among others— have tried to reconstruct the ontological assumptions of a language independent of the abstract phallogocentric logic, emerging by metonymic mediation from the maternal-material-matristic substrate, in essential continuity with that origin and immediate connection with life. In the context of this new maternal-matrix-material symbolic, this article aims to read Mistralian poetics, conceived and nurtured by the same matrix from which life is born.
van den Akker, Jeroen; Pistea, Adrian; Bakker, Erik N. T. P.; VanBavel, Ed
2008-01-01
Microvascular remodeling is known to depend on cellular interactions with matrix tissue. However, it is difficult to study the role of specific cells or matrix elements in an in vivo setting. The aim of this study is to develop an automated technique that can be employed to obtain and analyze local
Bildt, M.M.; Bloemen, M.; Kuijpers-Jagtman, A.M.; Hoff, J.W. Von den
2009-01-01
Orthodontic tooth movement requires extensive re-modelling of the periodontium. Matrix metalloproteinases (MMPs) degrade the extracellular matrix during re-modelling, while their activity is regulated by the tissue inhibitors of metalloproteinases (TIMPs). The aim of this study was to investigate
Bildt, Miriam; Bloemen, M; Kuijpers-Jagtman, A.M.; Von Den Hoff, Johannes W
2009-01-01
Orthodontic tooth movement requires extensive re-modelling of the periodontium. Matrix metalloproteinases (MMPs) degrade the extracellular matrix during re-modelling, while their activity is regulated by the tissue inhibitors of metalloproteinases (TIMPs). The aim of this study was to investigate
Integral-preserving integrators
International Nuclear Information System (INIS)
McLaren, D I; Quispel, G R W
2004-01-01
Ordinary differential equations having a first integral may be solved numerically using one of several methods, with the integral preserved to machine accuracy. One such method is the discrete gradient method. It is shown here that the order of the method can be bootstrapped repeatedly to higher orders of accuracy. The method is illustrated using the Henon-Heiles system. (letter to the editor)
Exact 2-point function in Hermitian matrix model
International Nuclear Information System (INIS)
Morozov, A.; Shakirov, Sh.
2009-01-01
J. Harer and D. Zagier have found a strikingly simple generating function [1,2] for exact (all-genera) 1-point correlators in the Gaussian Hermitian matrix model. In this paper we generalize their result to 2-point correlators, using Toda integrability of the model. Remarkably, this exact 2-point correlation function turns out to be an elementary function - arctangent. Relation to the standard 2-point resolvents is pointed out. Some attempts of generalization to 3-point and higher functions are described.
Inverse mass matrix via the method of localized lagrange multipliers
Czech Academy of Sciences Publication Activity Database
González, José A.; Kolman, Radek; Cho, S.S.; Felippa, C.A.; Park, K.C.
2018-01-01
Roč. 113, č. 2 (2018), s. 277-295 ISSN 0029-5981 R&D Projects: GA MŠk(CZ) EF15_003/0000493; GA ČR GA17-22615S Institutional support: RVO:61388998 Keywords : explicit time integration * inverse mass matrix * localized Lagrange multipliers * partitioned analysis Subject RIV: BI - Acoustics OBOR OECD: Applied mechanics Impact factor: 2.162, year: 2016 https://onlinelibrary.wiley.com/doi/10.1002/nme.5613
Weak matrix elements efforts on the lattice: Status and prospects
International Nuclear Information System (INIS)
Soni, A.
1995-01-01
Lattice approach to weak matrix elements is reviewed. Recent progress in treating heavy quarks on the lattice is briefly discussed. Illustrative sample of results obtained so far is given. Among them I elaborate on B K , line-integral B and B → K* γ . Experimental implications especially with regard to constraints on the Standard Model (i.e. Wolfenstein) parameters, V td measurements and expectations for B s -bar B s , oscillations are briefly discussed
Evaluation of lymphangiogenesis in acellular dermal matrix
Directory of Open Access Journals (Sweden)
Mario Cherubino
2014-01-01
Full Text Available Introduction: Much attention has been directed towards understanding the phenomena of angiogenesis and lymphangiogenesis in wound healing. Thanks to the manifold dermal substitute available nowadays, wound treatment has improved greatly. Many studies have been published about angiogenesis and cell invasion in INTEGRA® . On the other hand, the development of the lymphatic network in acellular dermal matrix (ADM is a more obscure matter. In this article, we aim to characterize the different phases of host cell invasion in ADM. Special attention was given to lymphangiogenic aspects. Materials and Methods: Among 57 rats selected to analyse the role of ADM in lymphangiogenesis, we created four groups. We performed an excision procedure on both thighs of these rats: On the left one we did not perform any action except repairing the borders of the wound; while on the right one we used INTEGRA® implant. The excision biopsy was performed at four different times: First group after 7 days, second after 14 days, third after 21 days and fourth after 28 days. For our microscopic evaluation, we used the classical staining technique of haematoxylin and eosin and a semi-quantitative method in order to evaluate cellularity counts. To assess angiogenesis and lymphangiogenesis development we employed PROX-1 Ab and CD31/PECAM for immunohistochemical analysis. Results: We found remarkable wound contraction in defects that healed by secondary intention while minor wound contraction was observed in defects treated with ADM. At day 7, optical microscopy revealed a more plentiful cellularity in the granulation tissue compared with the dermal regeneration matrix. The immunohistochemical process highlighted vascular and lymphatic cells in both groups. After 14 days a high grade of fibrosis was noticeable in the non-treated group. At day 21, both lymphatic and vascular endothelial cells were better developed in the group with a dermal matrix application. At day 28
q-Virasoro constraints in matrix models
Energy Technology Data Exchange (ETDEWEB)
Nedelin, Anton [Dipartimento di Fisica, Università di Milano-Bicocca and INFN, sezione di Milano-Bicocca, Piazza della Scienza 3, I-20126 Milano (Italy); Department of Physics and Astronomy, Uppsala university,Box 516, SE-75120 Uppsala (Sweden); Zabzine, Maxim [Department of Physics and Astronomy, Uppsala university,Box 516, SE-75120 Uppsala (Sweden)
2017-03-20
The Virasoro constraints play the important role in the study of matrix models and in understanding of the relation between matrix models and CFTs. Recently the localization calculations in supersymmetric gauge theories produced new families of matrix models and we have very limited knowledge about these matrix models. We concentrate on elliptic generalization of hermitian matrix model which corresponds to calculation of partition function on S{sup 3}×S{sup 1} for vector multiplet. We derive the q-Virasoro constraints for this matrix model. We also observe some interesting algebraic properties of the q-Virasoro algebra.
Immobilization of cellulase using porous polymer matrix
International Nuclear Information System (INIS)
Kumakura, M.; Kaetsu, I.
1984-01-01
A new method is discussed for the immobilization of cellulase using porous polymer matrices, which were obtained by radiation polymerization of hydrophilic monomers. In this method, the immobilized enzyme matrix was prepared by enzyme absorbtion in the porous polymer matrix and drying treatment. The enzyme activity of the immobilized enzyme matrix varied with monomer concentration, cooling rate of the monomer solution, and hydrophilicity of the polymer matrix, takinn the change of the nature of the porous structure in the polymer matrix. The leakage of the enzymes from the polymer matrix was not observed in the repeated batch enzyme reactions
Minimal solution for inconsistent singular fuzzy matrix equations
Directory of Open Access Journals (Sweden)
M. Nikuie
2013-10-01
Full Text Available The fuzzy matrix equations $Ailde{X}=ilde{Y}$ is called a singular fuzzy matrix equations while the coefficients matrix of its equivalent crisp matrix equations be a singular matrix. The singular fuzzy matrix equations are divided into two parts: consistent singular matrix equations and inconsistent fuzzy matrix equations. In this paper, the inconsistent singular fuzzy matrix equations is studied and the effect of generalized inverses in finding minimal solution of an inconsistent singular fuzzy matrix equations are investigated.
pyRMSD: a Python package for efficient pairwise RMSD matrix calculation and handling.
Gil, Víctor A; Guallar, Víctor
2013-09-15
We introduce pyRMSD, an open source standalone Python package that aims at offering an integrative and efficient way of performing Root Mean Square Deviation (RMSD)-related calculations of large sets of structures. It is specially tuned to do fast collective RMSD calculations, as pairwise RMSD matrices, implementing up to three well-known superposition algorithms. pyRMSD provides its own symmetric distance matrix class that, besides the fact that it can be used as a regular matrix, helps to save memory and increases memory access speed. This last feature can dramatically improve the overall performance of any Python algorithm using it. In addition, its extensibility, testing suites and documentation make it a good choice to those in need of a workbench for developing or testing new algorithms. The source code (under MIT license), installer, test suites and benchmarks can be found at https://pele.bsc.es/ under the tools section. victor.guallar@bsc.es Supplementary data are available at Bioinformatics online.
Giddings, Steven B
2010-01-01
We investigate the hypothesized existence of an S-matrix for gravity, and some of its expected general properties. We first discuss basic questions regarding existence of such a matrix, including those of infrared divergences and description of asymptotic states. Distinct scattering behavior occurs in the Born, eikonal, and strong gravity regimes, and we describe aspects of both the partial wave and momentum space amplitudes, and their analytic properties, from these regimes. Classically the strong gravity region would be dominated by formation of black holes, and we assume its unitary quantum dynamics is described by corresponding resonances. Masslessness limits some powerful methods and results that apply to massive theories, though a continuation path implying crossing symmetry plausibly still exists. Physical properties of gravity suggest nonpolynomial amplitudes, although crossing and causality constrain (with modest assumptions) this nonpolynomial behavior, particularly requiring a polynomial bound in c...