WorldWideScience

Sample records for integrating real life

  1. From real life to real life

    DEFF Research Database (Denmark)

    Svalgaard, Lotte

    2017-01-01

    In Action Learning programmes, it is held central to work on real business challenges (task) while learning about team and self (process); staying mindful aware of the process is referred to in this paper as ‘double awareness’, and emphasises noticing and acting on process cues while working on t...

  2. Bringing Abstract Academic Integrity and Ethical Concepts into Real-Life Situations

    Science.gov (United States)

    Kwong, Theresa; Wong, Eva; Yue, Kevin

    2017-01-01

    This paper reports the learning analytics on the initial stages of a large-scale, government-funded project which inducts university students in Hong Kong into consideration of academic integrity and ethics through mobile Augmented Reality (AR) learning trails--Trails of Integrity and Ethics (TIEs)--accessed on smart devices. The trails immerse…

  3. Operation of ULCS - real life

    Directory of Open Access Journals (Sweden)

    Jasna Prpić-Oršić

    2014-12-01

    Full Text Available In this paper the real life operation of ULCS (Ultra Large Container Ships is presented from the point of view of shipmasters. The paper provides interpretation of results of questionnaire filled by masters of large container ships during Tools for Ultra Large Container Ships (TULC EUI FP7 project. This is done in a way that results of questionnaire are further reviewed and commented by experienced master of ULCS. Following phenomena are subject of questionnaire and further discussed in the paper: parametric rolling, slamming, whipping, springing, green water and rogue waves. Special attention is given to the definition of rough sea states as well as to measures that ship masters take to avoid them as well as to the manoeuvring in heavy seas. The role of the wave forecast and weather routing software is also discussed.

  4. Measuring life by real people

    DEFF Research Database (Denmark)

    Hansen, Ellen Kathrine

    2010-01-01

    This article describes how information about Active House is obtained through tests done on demonstration buildings. Tests in which life in intelligent and energy-optimised homes takes centre stage, and where ratings are obtained via human behaviour and wellbeing. The article also describes exper...

  5. Real Life Lab BIPV field testing in the Netherlands

    NARCIS (Netherlands)

    Ritzen, M.; Vroon, Z.; Rovers, R.; Geurts, C.; Blocken, B.

    2015-01-01

    Integration of PV in the Building Envelope (BIPV) is one of the four key developments necessary for large market PV penetration, together with PV efficiency improvement, price decrease and electricity storage [1]. In the course of BIPV development, Real-Life Lab demonstration projects are realized

  6. Real life lab BIPV field testing in the Netherlands

    NARCIS (Netherlands)

    Ritzen, M.J.; Vroon, Z.; Geurts, C.P.W.; Rovers, R.; Blocken, B.J.E.

    2015-01-01

    Integration of PV in the Building Envelope (BIPV) is one of the four key developments necessary for large market PV penetration, together with PV efficiency improvement, price decrease and electricity storage [1]. In the course of BIPV development, Real-Life Lab demonstration projects are realized

  7. LabVIEW A Developer's Guide to Real World Integration

    CERN Document Server

    Fairweather, Ian

    2011-01-01

    LabVIEW(t) has become one of the preeminent platforms for the development of data acquisition and data analysis programs. LabVIEW(t): A Developer's Guide to Real World Integration explains how to integrate LabVIEW into real-life applications. Written by experienced LabVIEW developers and engineers, the book describes how LabVIEW has been pivotal in solving real-world challenges. Each chapter is self-contained and demonstrates the power and simplicity of LabVIEW in various applications, from image processing to solar tracking systems. Many of the chapters explore how exciting new technologies c

  8. Endangered Species: Real Life in Two Dimensions

    Science.gov (United States)

    Henderson, Lynette K.

    2012-01-01

    The focus of "Endangered Species: Real Life in Two Dimensions" is to create awareness about a critical environmental issue. There is a special urgency to this project because large numbers of animal species are currently endangered or on the brink of extinction. In addition to being enlightened about this important topic through research, students…

  9. Solving Real-Life Problems: Future Mobile Technology Sophistication

    Directory of Open Access Journals (Sweden)

    FARHAN SHAFIQ

    2016-07-01

    Full Text Available Almost all the human being real life concerned domains are taking advantage of latest technologies for enhancing their process, procedures and operations. This integration of technological innovations provides ease of access, flexibility, transparency, reliability and speed for the concerned process and procedures. Rapid growth of ICT (Information and Communication Technology and MT (Mobile Technology provides opportunity to redesign and reengineered the human routines? life activities process and procedures. Technology integration and adoption in routine life activities may serves compensatory mechanism to assist the population in different manner such as monitoring older adults and children at homes, provides security assistance, monitoring and recording patients vital signs automatically, controlling and monitoring equipments and devices, providing assistance in shopping, banking and education as well. Disasters happened suddenly, destroy everything indiscriminately. Adoption and integration of latest technologies including ICT and MT can enhance the current disaster management process, procedures and operations. This research study focuses the impacts of latest and emerging technology trends in routine life activities and surrounds their potential strength to improve and enhance disaster management activities. MT is providing a promising platform for facilitating people to enhance their routine life activities. This research argue that integration and adoption of mobile computing in disaster management domain can enhance disaster management activities with promising minimizing error, quick information assembling, quick response based on technology manipulation and prioritizing action.

  10. Solving real-life problems: future mobile technology sophistication

    International Nuclear Information System (INIS)

    Shafiq, F.; Ahsan, K.; Nadeem, A.

    2016-01-01

    Almost all the human being real life concerned domains are taking advantage of latest technologies for enhancing their process, procedures and operations. This integration of technological innovations provides ease of access, flexibility, transparency, reliability and speed for the concerned process and procedures. Rapid growth of ICT (Information and Communication Technology) and MT (Mobile Technology) provides opportunity to redesign and re-engineered the human routines life activities process and procedures. Technology integration and adoption in routine life activities may serves compensatory mechanism to assist the population in different manner such as monitoring older adults and children at homes, provides security assistance, monitoring and recording patients vital signs automatically, controlling and monitoring equipments and devices, providing assistance in shopping, banking and education as well. Disasters happened suddenly, destroy everything indiscriminately. Adoption and integration of latest technologies including ICT and MT can enhance the current disaster management process, procedures and operations. This research study focuses the impacts of latest and emerging technology trends in routine life activities and surrounds their potential strength to improve and enhance disaster management activities. MT is providing a promising platform for facilitating people to enhance their routine life activities. This research argue that integration and adoption of mobile computing in disaster management domain can enhance disaster management activities with promising minimizing error, quick information assembling, quick response based on technology manipulation and prioritizing action. (author)

  11. Real-life applications with membrane computing

    CERN Document Server

    Zhang, Gexiang; Gheorghe, Marian

    2017-01-01

    This book thoroughly investigates the underlying theoretical basis of membrane computing models, and reveals their latest applications. In addition, to date there have been no illustrative case studies or complex real-life applications that capitalize on the full potential of the sophisticated membrane systems computational apparatus; gaps that this book remedies. By studying various complex applications – including engineering optimization, power systems fault diagnosis, mobile robot controller design, and complex biological systems involving data modeling and process interactions – the book also extends the capabilities of membrane systems models with features such as formal verification techniques, evolutionary approaches, and fuzzy reasoning methods. As such, the book offers a comprehensive and up-to-date guide for all researchers, PhDs and undergraduate students in the fields of computer science, engineering and the bio-sciences who are interested in the applications of natural computing models.

  12. Disease spreading in real-life networks

    Science.gov (United States)

    Gallos, Lazaros; Argyrakis, Panos

    2002-08-01

    In recent years the scientific community has shown a vivid interest in the network structure and dynamics of real-life organized systems. Many such systems, covering an extremely wide range of applications, have been recently shown to exhibit scale-free character in their connectivity distribution, meaning that they obey a power law. Modeling of epidemics on lattices and small-world networks suffers from the presence of a critical infection threshold, above which the entire population is infected. For scale-free networks, the original assumption was that the formation of a giant cluster would lead to an epidemic spreading in the same way as in simpler networks. Here we show that modeling epidemics on a scale-free network can greatly improve the predictions on the rate and efficiency of spreading, as compared to lattice models and small-world networks. We also show that the dynamics of a disease are greatly influenced by the underlying population structure. The exact same model can describe a plethora of networks, such as social networks, virus spreading in the Web, rumor spreading, signal transmission etc.

  13. Scientist-teacher collaboration: Integration of real data from a coastal wetland into a high school life science ecology-based research project

    Science.gov (United States)

    Hagan, Wendy L.

    Project G.R.O.W. is an ecology-based research project developed for high school biology students. The curriculum was designed based on how students learn and awareness of the nature of science and scientific practices so that students would design and carry out scientific investigations using real data from a local coastal wetland. This was a scientist-teacher collaboration between a CSULB biologist and high school biology teacher. Prior to implementing the three-week research project, students had multiple opportunities to practice building requisite skills via 55 lessons focusing on the nature of science, scientific practices, technology, Common Core State Standards of reading, writing, listening and speaking, and Next Generation Science Standards. Project G.R.O.W. culminated with student generated research papers and oral presentations. Outcomes reveal students struggle with constructing explanations and the use of Excel to create meaningful graphs. They showed gains in data organization, analysis, teamwork and aspects of the nature of science.

  14. Accounting Theory: An Ethical Perspective of Real Life Scenarios

    Directory of Open Access Journals (Sweden)

    Shivneil Kumar Raj

    2016-11-01

    Full Text Available Decisions are made daily in businesses and individuals do encounter situations where they are faced with ethical issues. The subject is how one evaluates whether an act is ethical or unethical. This research article discusses real life ethical dilemmas that could be faced in accounting or business environment and applicability of various theories of ethics that were taught in accounting theory course in the undergraduate accounting program. The researcher employs a number of case studies highlighting the stories related to ethics that have been experienced in the past working life. Teleological and deontological theories are being used to explain how one could identify that a particular act is ethical or unethical. The work of accountants requires them to maintain high level of ethics to ensure integrity of the profession.

  15. Technical life cycle of real estates

    OpenAIRE

    Taina Koskelo

    2001-01-01

    Real estate business is developing fast. Development needs are challenging because of interdiciplinariness and diverseness of the branch. The main mission of real estate business is to provide premises for its customers. Designers are planning the buildings, contractors are building them and owners are supplying premises for users. During the use the real estate market needs different kinds of facilitating services directed to users or owner of buildings. Facilities Management services (FM) c...

  16. Gamer Girls, Gold Farmers, and Activism "In Real Life"

    Science.gov (United States)

    Musgrave, Megan L.

    2016-01-01

    This essay analyzes the graphic novel "In Real Life" as an example of Cory Doctorow and Jen Wang's intention to raise young people's awareness about gender and economic disparities within the gaming industry. Broadly, "In Real Life" combats the pervasive cultural anxiety that Jane McGonigal challenges in her book "Reality…

  17. Implication of Integrative Treatment Strategies for Real-Life Geriatric Patients with Multiple, Chronic Illnesses: A 60-Month Follow-Up of a Naturalistic Study

    Directory of Open Access Journals (Sweden)

    Gjumrakch Aliev

    2015-03-01

    Full Text Available Neurodegeneration [Stroke and Alzheimer disease (AD] is fastly becoming one of the leading causes of age-associated disability, dementia, and death. In addition, the Centers for Disease Control and Prevention (CDC and the National Center for Health Statistics recently reported that AD has surpassed diabetes as a leading cause of death and is now considered the sixth-leading cause of death in the United States. Unfortunately, currently no effective treatments are available against this devastating disease. In the past we have shown the preservation and improvement of cognitive tasks in depressed and demented patients after 24 and 36 months of combined pharmacological and non- pharmacological treatment. Here we present the results of our ongoing, naturalistic study, in the same outpatient setting, at the 60 month follow up. The study group consisted of 156 medically ill, physically-disabled patients with mild to moderate dementia and depression. Patients were treated with antidepressants, cholinesterase inhibitors, and NMDA antagonists, along with their regular medication regimen. Non-pharmacological intervention was centered on a home-based program of physical and cognitive exercises as well as with vitamins and supplements (multivitamins, vitamin E, L-methylfolate, alpha-lipoic acid, acetyl-l-carnitine, omega-3, and coenzyme Q-10 and diet modification. Cognitive assessments were performed yearly. After 60 months of treatment, performance of all tasks remained at or above baseline. The MMSE, Cognistat–Attention, Cognistat–Judgment, and RFFT - Total Unique Designs demonstrated significant improvement. Our results, for the first time, demonstrate arrest in cognitive decline in demented/depressed patients with multiple medical co-morbidities for 60 months. Future investigations addressing the application of a combined, integrative treatment models in clinical practices are warranted.

  18. Speed Biases With Real-Life Video Clips

    Directory of Open Access Journals (Sweden)

    Federica Rossi

    2018-03-01

    Full Text Available We live almost literally immersed in an artificial visual world, especially motion pictures. In this exploratory study, we asked whether the best speed for reproducing a video is its original, shooting speed. By using adjustment and double staircase methods, we examined speed biases in viewing real-life video clips in three experiments, and assessed their robustness by manipulating visual and auditory factors. With the tested stimuli (short clips of human motion, mixed human-physical motion, physical motion and ego-motion, speed underestimation was the rule rather than the exception, although it depended largely on clip content, ranging on average from 2% (ego-motion to 32% (physical motion. Manipulating display size or adding arbitrary soundtracks did not modify these speed biases. Estimated speed was not correlated with estimated duration of these same video clips. These results indicate that the sense of speed for real-life video clips can be systematically biased, independently of the impression of elapsed time. Measuring subjective visual tempo may integrate traditional methods that assess time perception: speed biases may be exploited to develop a simple, objective test of reality flow, to be used for example in clinical and developmental contexts. From the perspective of video media, measuring speed biases may help to optimize video reproduction speed and validate “natural” video compression techniques based on sub-threshold temporal squeezing.

  19. An integrated technique for developing real-time systems

    NARCIS (Netherlands)

    Hooman, J.J.M.; Vain, J.

    1995-01-01

    The integration of conceptual modeling techniques, formal specification, and compositional verification is considered for real time systems within the knowledge engineering context. We define constructive transformations from a conceptual meta model to a real time specification language and give

  20. An adaptation framework for turning real life events into games

    DEFF Research Database (Denmark)

    Therkildsen, Sacha Kjærhus; Bunkenborg, Nanna Cassøe; Larsen, Lasse Juel

    2017-01-01

    Many games are inspired by real life events. The presented adaptation framework is based on the design of a board game with a companion app that addresses the Syrian refugee crisis. The aim of the game is to allow players to simulate the experience of being a Syrian refugee traveling through Europe....... We applied an agile development method and participatory design to achieve our ambition. In conclusion we found that turning real life events into board games can be advanced by the following game design adaptation framework, which balances four interrelated layers: (1) real life events (game fiction...

  1. Competence and Quality in Real-Life Decision Making

    OpenAIRE

    Geisler, Martin; Allwood, Carl Martin

    2015-01-01

    What distinguishes a competent decision maker and how should the issue of decision quality be approached in a real-life context? These questions were explored in three studies. In Study 1, using a web-based questionnaire and targeting a community sample, we investigated the relationships between objective and subjective indicators of real-life decision-making success. In Study 2 and 3, targeting two different samples of professionals, we explored if the prevalent cognitively oriented definiti...

  2. When Cognitive Sciences Meet Real Life

    DEFF Research Database (Denmark)

    Smith, Viktor; Selsøe Sørensen, Henrik; Nissilä, Niina

    2012-01-01

    Consumers in general pay little attention to food labels. The study of expert-to-layperson communication related to food labels integrates many aspects of what cognitive sciences are about: Knowledge modelling and knowledge transfer, termhood and precision as well as fuzziness, interaction between...

  3. Integrating Real-time Earthquakes into Natural Hazard Courses

    Science.gov (United States)

    Furlong, K. P.; Benz, H. M.; Whitlock, J. S.; Bittenbinder, A. N.; Bogaert, B. B.

    2001-12-01

    Natural hazard courses are playing an increasingly important role in college and university earth science curricula. Students' intrinsic curiosity about the subject and the potential to make the course relevant to the interests of both science and non-science students make natural hazards courses popular additions to a department's offerings. However, one vital aspect of "real-life" natural hazard management that has not translated well into the classroom is the real-time nature of both events and response. The lack of a way to entrain students into the event/response mode has made implementing such real-time activities into classroom activities problematic. Although a variety of web sites provide near real-time postings of natural hazards, students essentially learn of the event after the fact. This is particularly true for earthquakes and other events with few precursors. As a result, the "time factor" and personal responsibility associated with natural hazard response is lost to the students. We have integrated the real-time aspects of earthquake response into two natural hazard courses at Penn State (a 'general education' course for non-science majors, and an upper-level course for science majors) by implementing a modification of the USGS Earthworm system. The Earthworm Database Management System (E-DBMS) catalogs current global seismic activity. It provides earthquake professionals with real-time email/cell phone alerts of global seismic activity and access to the data for review/revision purposes. We have modified this system so that real-time response can be used to address specific scientific, policy, and social questions in our classes. As a prototype of using the E-DBMS in courses, we have established an Earthworm server at Penn State. This server receives national and global seismic network data and, in turn, transmits the tailored alerts to "on-duty" students (e-mail, pager/cell phone notification). These students are responsible to react to the alarm

  4. Real life working shift assignment problem

    Science.gov (United States)

    Sze, San-Nah; Kwek, Yeek-Ling; Tiong, Wei-King; Chiew, Kang-Leng

    2017-07-01

    This study concerns about the working shift assignment in an outlet of Supermarket X in Eastern Mall, Kuching. The working shift assignment needs to be solved at least once in every month. Current approval process of working shifts is too troublesome and time-consuming. Furthermore, the management staff cannot have an overview of manpower and working shift schedule. Thus, the aim of this study is to develop working shift assignment simulation and propose a working shift assignment solution. The main objective for this study is to fulfill manpower demand at minimum operation cost. Besides, the day off and meal break policy should be fulfilled accordingly. Demand based heuristic is proposed to assign working shift and the quality of the solution is evaluated by using the real data.

  5. Contextualizing Performances: Comparing Performances during TOEFL iBT™ and Real-Life Academic Speaking Activities

    Science.gov (United States)

    Brooks, Lindsay; Swain, Merrill

    2014-01-01

    In this study we compare test takers' performance on the Speaking section of the TOEFL iBT™and their performances during their real-life academic studies. Thirty international graduate students from mixed language backgrounds in two different disciplines (Sciences and Social Sciences) responded to two independent and four integrated speaking tasks…

  6. Integration of MDSplus in real-time systems

    International Nuclear Information System (INIS)

    Luchetta, A.; Manduchi, G.; Taliercio, C.

    2006-01-01

    RFX-mod makes extensive usage of real-time systems for feedback control and uses MDSplus to interface them to the main Data Acquisition system. For this purpose, the core of MDSplus has been ported to VxWorks, the operating system used for real-time control in RFX. Using this approach, it is possible to integrate real-time systems, but MDSplus is used only for non-real-time tasks, i.e. those tasks which are executed before and after the pulse and whose performance does not affect the system time constraints. More extensive use of MDSplus in real-time systems is foreseen, and a real-time layer for MDSplus is under development, which will provide access to memory-mapped pulse files, shared by the tasks running on the same CPU. Real-time communication will also be integrated in the MDSplus core to provide support for distributed memory-mapped pulse files

  7. Real-Life Efficacy, Immunogenicity and Safety of Biosimilar Infliximab.

    Science.gov (United States)

    Vegh, Zsuzsanna; Kurti, Zsuzsanna; Lakatos, Peter L

    2017-01-01

    Recently, the use of biosimilar infliximab (IFX) in the treatment of inflammatory bowel diseases has become widespread in some European and non-European countries. Data on the efficacy, safety and immunogenicity from real-life cohorts are accumulating. The first reports showed similar outcomes in the induction and maintenance of remission, mucosal healing, safety and immunogenicity profile to the originator IFX. In the present review, we aimed to summarize the existing knowledge on the efficacy, safety and immunogenicity profile of biosimilar IFX reported from real-life cohorts. © 2017 S. Karger AG, Basel.

  8. "Real-life" treatment of chronic pain: Targets and goals.

    Science.gov (United States)

    Ablin, Jacob N; Buskila, Dan

    2015-02-01

    Treating chronic pain is a complex challenge. While textbooks and medical education classically categorize pain as originating from peripheral (nociceptive), neuropathic, or centralized origins, in real life each and every patient may present a combination of various pain sources, types, and mechanisms. Moreover, individual patients may evolve and develop differing types of pain throughout their clinical follow-up, further emphasizing the necessity to maintain clinical diligence during the evaluation and follow-up of these patients. Rational treatment of patients suffering from chronic pain must attempt at deconstructing complex pain cases, identifying variegate pain generators, and targeting them with appropriate interventions, while incorporating both pharmacological and non-pharmacological strategies, rather than focusing on the total pain level, which represents an integral of all pain types. Failing to recognize the coexistence of different types of pain in an individual patient and escalating medications only on the basis of total pain intensity are liable to lead to both ineffective control of pain and increased untoward effects. In the current review, we outline strategies for deconstructing complex pain and therapeutic suggestions. Copyright © 2015 Elsevier Ltd. All rights reserved.

  9. Integrating Sustainability into the Real Estate Valuation Process: A ...

    African Journals Online (AJOL)

    This paper sought the perception of Nigerian real estate valuers on sustainable development and how sustainability can be integrated into the real estate valuation process in Nigeria. One hundred and sixty Estate Surveyors and Valuers were asked, among others, to rate the significance of a range of sustainability features ...

  10. Privatization of Land Plot Under Integral Real Estate Complex

    Directory of Open Access Journals (Sweden)

    Maruchek A. A.

    2014-10-01

    Full Text Available The article deals with the questions concerning the privatization of a land plot under integral real estate complex. The authors come to conclusion that a number of legislation norms relating to privatization of a land plot do not take into account the construction of an integral real estate complex that could cause some problems in the realization of the right to privatization of the land plot

  11. Beyond Work-Life "Integration".

    Science.gov (United States)

    Williams, Joan C; Berdahl, Jennifer L; Vandello, Joseph A

    2016-01-01

    Research on the work-family interface began in the 1960s and has grown exponentially ever since. This vast amount of research, however, has had relatively little impact on workplace practice, and work-family conflict is at an all-time high. We review the work-family research to date and propose that a shift of attention is required, away from the individual experience of work and family and toward understanding how identity and status are defined at work. Several factors enshrine cherished identities around current workplace norms. The work devotion schema demands that those who are truly committed to their work will make it the central or sole focus of their lives, without family demands to distract them. Importantly, the work devotion schema underwrites valued class and gender identities: Work devotion is a key way of enacting elite class status and functions as the measure of a man--the longer the work hours and higher the demand for his attention, the better. Advocating change in the way work is done and life is lived meets resistance because it places these cherished identities at risk. Resistance to these identity threats keeps current workplace norms in place. This is why even the business case-which shows that current practices are not economically efficient-fails to persuade organizations to enact change. What is needed now is sustained attention to the implicit psychological infrastructure that cements the mismatch between today's workplace and today's workforce.

  12. Children's Eyewitness Memory for Multiple Real-Life Events

    Science.gov (United States)

    Odegard, Timothy N.; Cooper, Crystal M.; Lampinen, James M.; Reyna, Valerie F.; Brainerd, Charles J.

    2009-01-01

    The present research examined the influence of prior knowledge on children's free recall, cued recall, recognition memory, and source memory judgments for a series of similar real-life events. Forty children (5-12 years old) attended 4 thematic birthday parties and were later interviewed about the events that transpired during the parties using…

  13. Improvisation of Real-Life Scenarios through Intercultural Competence

    Science.gov (United States)

    Okten, Celile Eren; Griffin, Banu Ozer

    2016-01-01

    This paper describes tasks based on real-life scenarios, which triggered reflective thinking, verbalization, and writing, leading to the creation of natural dialogues rather than artificial, dull monologues. One of the main aims of this approach is to engage students in a dynamic process of both learning about multicultural participants and…

  14. Rendezvous with IQ: Metacognition in Real-Life Situations

    Science.gov (United States)

    Al-Hilawani, Yasser A.

    2018-01-01

    The purpose of this study was to examine the relationship between metacognition as measured in real-life situations and IQ scores as reflected by performance on the Raven Standard Progressive Matrices Scale. It is also intended in this study to report on whether or not there were significant differences in performance on the metacognitive…

  15. Competence and Quality in Real-Life Decision Making

    Science.gov (United States)

    2015-01-01

    What distinguishes a competent decision maker and how should the issue of decision quality be approached in a real-life context? These questions were explored in three studies. In Study 1, using a web-based questionnaire and targeting a community sample, we investigated the relationships between objective and subjective indicators of real-life decision-making success. In Study 2 and 3, targeting two different samples of professionals, we explored if the prevalent cognitively oriented definition of decision-making competence could be beneficially expanded by adding aspects of competence in terms of social skills and time-approach. The predictive power for each of these three aspects of decision-making competence was explored for different indicators of real-life decision-making success. Overall, our results suggest that research on decision-making competence would benefit by expanding the definition of competence, by including decision-related abilities in terms of social skills and time-approach. Finally, the results also indicate that individual differences in real-life decision-making success profitably can be approached and measured by different criteria. PMID:26545239

  16. Competence and Quality in Real-Life Decision Making.

    Science.gov (United States)

    Geisler, Martin; Allwood, Carl Martin

    2015-01-01

    What distinguishes a competent decision maker and how should the issue of decision quality be approached in a real-life context? These questions were explored in three studies. In Study 1, using a web-based questionnaire and targeting a community sample, we investigated the relationships between objective and subjective indicators of real-life decision-making success. In Study 2 and 3, targeting two different samples of professionals, we explored if the prevalent cognitively oriented definition of decision-making competence could be beneficially expanded by adding aspects of competence in terms of social skills and time-approach. The predictive power for each of these three aspects of decision-making competence was explored for different indicators of real-life decision-making success. Overall, our results suggest that research on decision-making competence would benefit by expanding the definition of competence, by including decision-related abilities in terms of social skills and time-approach. Finally, the results also indicate that individual differences in real-life decision-making success profitably can be approached and measured by different criteria.

  17. Real-Life Research: Project Runway Makeover Model

    Science.gov (United States)

    Jaeger, Paige; Nesi, Olga M.

    2014-01-01

    Real-life research is incredibly varied. We research cars. We research lawn problems. We research child behavior problems, health issues, possible vacation destinations, and prices to stretch our budgets. No two scenarios are ever alike, and no two health issues should be assumed to be the same. That is reality, and that is a picture of what the…

  18. Clinical and economic impact of etanercept in real-life

    DEFF Research Database (Denmark)

    Larsen, Christian Grønhøj; Andersen, Peter Hundevadt; Lorentzen, Henrik

    2013-01-01

    BACKGROUND: Real-life data on the therapeutic effectiveness and costs of etanercept are scarce. Objectives: To assess the clinical and economic impact of etanercept in patients with psoriasis in Denmark and Norway. MATERIAL & METHODS: This prospective, non-interventional study in a private...

  19. The Real World around me – Life within the Pixel?

    Directory of Open Access Journals (Sweden)

    Aleksandra Bokan

    2015-09-01

    Full Text Available Modern era, the famous 21st century is full of options. Never more features and never greater alienation. Is it really so? While living in their standard-progress that, but when it towered over the black shadow, and when you are able to save someone’s life, tripping locked mechanisms for social survival. It no longer matters whether someone look at someone elses’s pictures from the wedding, showing a new hairstyle on FB or Twitter etc. Simply put, life on the Internet becomes a means of saving someone’s real, tangible life.

  20. Mathematics and engineering in real life through mathematical competitions

    Science.gov (United States)

    More, M.

    2018-02-01

    We bring out an experience of organizing mathematical competitions that can be used as a medium to motivate the student and teacher minds in new directions of thinking. This can contribute to fostering research, innovation and provide a hands-on experience of mathematical concepts with the real world. Mathematical competitions can be used to build curiosity and give an understanding of mathematical applications in real life. Participation in the competition has been classified under four broad categories. Student can showcase their findings in various forms of expression like model, poster, soft presentation, animation, live performance, art and poetry. The basic focus of the competition is on using open source computation tools and modern technology, to emphasize the relationship of mathematical concepts with engineering applications in real life.

  1. Real Convergence, Steps from Adherence to Integration

    Directory of Open Access Journals (Sweden)

    Mihail Busu

    2016-05-01

    Full Text Available The macroeconomic model Solow-Swan shows that the marginal rates of capital, technology and labor force, with positive values, have the capacity to stimulate the economic growth of the emergent economies, as in the case of Romania, for the 2005-2014 period, facilitating the determination of specific correlations between macroeconomic indicators to analyze the convergence towards the average European Union (EU. The economic theory, highlighted in particular by the Solow-Swan model, was applied in the current paper, to determine the potential of real convergence. Moreover, the statistics for the period 2005-2014 facilitated the analysis of the growth and recession factors specific to economies of Central and Eastern Europe and placed Romania amongst the EU countries with emergent economies and potential of economic growth. The European Commission’s reports regarding the macroeconomic imbalance procedure draw attention on the same indicators presented in the article to address proper recommendations and support corrective measures. Making a step from nominal to real convergence, the latter derives naturally from the need to recoup the gaps in comparison with developed economies amongst countries of the Euro Area.

  2. Transition to life--a sendoff to the real world for graduating medical students.

    Science.gov (United States)

    Coates, Wendy C; Spector, Tahlia S; Uijtdehaage, Sebastian

    2012-01-01

    Graduating medical students will enter the workforce, often for the first time. Many have spent the past 20 years as students, receiving financial support from parents, and have not managed real-life issues such as financial planning, real estate, balancing well-being with employment, and integrating into a new community with stressful working conditions. To address a perceived need, we designed an intervention to introduce graduating medical students to financial planning, real estate choices, physician wellness during relocation/internship, and traits of efficient interns. The objectives of this study are to (a) assess baseline experience, knowledge, and comfort of seniors about "real-life" experiences, and (b) assess the efficacy of a 4-hr educational intervention on perceptions of understanding financial planning, real estate choices, intern preparedness, and physician wellness. Acute Care College seniors (classes of 2009 and 2010) attended the intervention after match day and completed a survey to gather demographic data and assess preexisting knowledge and a postintervention survey (1-7 Likert scale). Forty-nine students (45% male; M age = 25.5 years) participated. Prior experiences: 43% no break in education, 51% no full-time job, 38% never signed a rental lease and 94% had not purchased real estate, 90% did not have (or were not aware of having) disability insurance, and 82% had educational debt exceeding $50,000. Following the workshop, students felt more confident in their understanding of life skills topics (real estate, 83%; financial planning, 94%; well-being, 86%). Our workshop assisted in preparing for life after medical school for 98% of the participants. Graduating medical students can gain knowledge about real-life responsibilities and confidence during an educational session prior to starting residency.

  3. CANDU plant life management - An integrated approach

    International Nuclear Information System (INIS)

    Hopkins, J.R.

    1998-01-01

    An integrated approach to plant life management has been developed for CANDU reactors. Strategies, methods, and procedures have been developed for assessment of critical systems structures and components and for implementing a reliability centred maintenance program. A Technology Watch program is being implemented to eliminate 'surprises'. Specific work has been identified for 1998. AECL is working on the integrated program with CANDU owners and seeks participation from other CANDU owners

  4. Advanced integrated real-time clinical displays.

    Science.gov (United States)

    Kruger, Grant H; Tremper, Kevin K

    2011-09-01

    Intelligent medical displays have the potential to improve patient outcomes by integrating multiple physiologic signals, exhibiting high sensitivity and specificity, and reducing information overload for physicians. Research findings have suggested that information overload and distractions caused by patient care activities and alarms generated by multiple monitors in acute care situations, such as the operating room and the intensive care unit, may produce situations that negatively impact the outcomes of patients under anesthesia. This can be attributed to shortcomings of human-in-the-loop monitoring and the poor specificity of existing physiologic alarms. Modern artificial intelligence techniques (ie, intelligent software agents) are demonstrating the potential to meet the challenges of next-generation patient monitoring and alerting. Copyright © 2011 Elsevier Inc. All rights reserved.

  5. Virtually numbed: immersive video gaming alters real-life experience.

    Science.gov (United States)

    Weger, Ulrich W; Loughnan, Stephen

    2014-04-01

    As actors in a highly mechanized environment, we are citizens of a world populated not only by fellow humans, but also by virtual characters (avatars). Does immersive video gaming, during which the player takes on the mantle of an avatar, prompt people to adopt the coldness and rigidity associated with robotic behavior and desensitize them to real-life experience? In one study, we correlated participants' reported video-gaming behavior with their emotional rigidity (as indicated by the number of paperclips that they removed from ice-cold water). In a second experiment, we manipulated immersive and nonimmersive gaming behavior and then likewise measured the extent of the participants' emotional rigidity. Both studies yielded reliable impacts, and thus suggest that immersion into a robotic viewpoint desensitizes people to real-life experiences in oneself and others.

  6. Real analysis an introduction to the theory of real functions and integration

    CERN Document Server

    Dshalalow, Jewgeni H

    2000-01-01

    Designed for use in a two-semester course on abstract analysis, REAL ANALYSIS: An Introduction to the Theory of Real Functions and Integration illuminates the principle topics that constitute real analysis. Self-contained, with coverage of topology, measure theory, and integration, it offers a thorough elaboration of major theorems, notions, and constructions needed not only by mathematics students but also by students of statistics and probability, operations research, physics, and engineering.Structured logically and flexibly through the author''s many years of teaching experience, the material is presented in three main sections:Part 1, chapters 1through 3, covers the preliminaries of set theory and the fundamentals of metric spaces and topology. This section can also serves as a text for first courses in topology.Part II, chapter 4 through 7, details the basics of measure and integration and stands independently for use in a separate measure theory course.Part III addresses more advanced topics, includin...

  7. A unified approach to stochastic integration on the real line

    DEFF Research Database (Denmark)

    Basse-O'Connor, Andreas; Graversen, Svend-Erik; Pedersen, Jan

    Stochastic integration on the predictable σ-field with respect to σ-finite L0-valued measures, also known as formal semimartingales, is studied. In particular, the triplet of such measures is introduced and used to characterize the set of integrable processes. Special attention is given to Lévy...... processes indexed by the real line. Surprisingly, many of the basic properties break down in this situation compared to the usual R+ case....

  8. CANDU plant life management - An integrated approach

    International Nuclear Information System (INIS)

    Charlebois, P.; Hart, R.S.; Hopkins, J.R.

    1998-01-01

    Commercial versions of CANDU reactors were put into service starting more than 25 years ago. The first unit of Ontario Hydro's Pickering A station was put into service in 1971, and Bruce A in 1977. Most CANDU reactors, however, are only now approaching their mid-life of 15 to 20 years of operation. In particular, the first series of CANDU 6 plants which entered service in the early 1980's were designed for a 30 year life and are now approaching mid life. The current CANDU 6 design is based on a 40 year life as a result of advancement in design and materials through research and development. In order to assure safe and economic operation of these reactors, a comprehensive CANDU Plant Life Management (PLIM) program is being developed from the knowledge gained during the operation of Ontario Hydro's Pickering, Bruce, and Darlington stations, worldwide information from CANDU 6 stations, CANDU research and development programs, and other national and international sources. This integration began its first phase in 1994, with the identification of most of the critical systems structures and components in these stations, and a preliminary assessment of degradation and mechanisms that could affect their fitness for service for their planned life. Most of these preliminary assessments are now complete, together with the production of the first iteration of Life Management Plans for several of the systems and components. The Generic CANDU 6 PLIM program is now reaching its maturity, with formal processes to systematically identify and evaluate the major CSSCs in the station, and a plan to ensure that the plant surveillance, operation, and maintenance programs monitor and control component degradation well within the original design specifications essential for the plant life attainment. A Technology Watch program is being established to ensure that degradation mechanisms which could impact on plant life are promptly investigated and mitigating programs established. The

  9. Integrating a virtual agent into the real world

    OpenAIRE

    André, Elisabeth

    2007-01-01

    Integrating a virtual agent into the real world : the virtual anatomy assistant ritchie / K. Dorfmüller-Ulhaas ... - In: Intelligent virtual agents : 7th international conference, IVA 2007, Paris, France, September 17-19, 2007 ; proceedings / Catherine Pelachaud ... (eds.). - Berlin [u.a.] : Springer, 2007. - S. 211-224. - (Lecture notes in computer science ; 4722 : Lecture notes in artificial intelligence)

  10. Intriguingly Real Life of the Queen of Crime

    Directory of Open Access Journals (Sweden)

    Branka Kovačević

    2016-12-01

    Full Text Available This December it will be ninety years since Agatha Christie disappeared for eleven days and despite the fact that there are many biographical books about her life and work, nobody knows for sure what provoked her to vanish, sending shockwaves in British society in 1926. Whatever the cause may be, this disappearance has remained a mystery and inspired French authors Anne Martinetti and Guillaume Lebeau, along with the illustrator Alexandre Franc, to create a graphic novel: Agatha: The Real Life of Agatha Christie. Marinetti has also written a cookbook inspired by Agatha Christie, entitled Creams and Punishments, while together with Lebeau, she has co-authored the encyclopedia Agatha Christie from A to Z.Agatha: The Real Life of Agatha Christie was originally released in 2014 as a French-language Kindle edition and was first published in English in May, 2016 by the UK press SelfMadeHero, which specializes in graphic novels and manga adaptations of classic literature, like those of Shakespeare, Poe and Kafka. The story is told through 112 illustrated pages and concludes with a thorough timeline of key events in Agatha Christie’s life, as well as a complete bibliography. It is noticeable that novels and story collections featuring Hercule Poirot take up the greater part of her bibliography. The authors of this biography assume a similar approach in showing the significance of this fictional character in Christie's career (and life, representing Poirot throughout the text as her companion and advisor without using any graphic techniques to stress the fictionality of his character. The authors make strong attempts to convey the close relationship that Christie built with her most prominent character, one who always seems to appear in this biography during her moments of extreme loneliness, and one to whom Christie owed a great deal – as she admited herself when she decided to buy the Greenway House in December 1938 (Martinetti, Lebeau, and Franc

  11. Real analysis measure theory, integration, and Hilbert spaces

    CERN Document Server

    Stein, Elias M

    2005-01-01

    Real Analysis is the third volume in the Princeton Lectures in Analysis, a series of four textbooks that aim to present, in an integrated manner, the core areas of analysis. Here the focus is on the development of measure and integration theory, differentiation and integration, Hilbert spaces, and Hausdorff measure and fractals. This book reflects the objective of the series as a whole: to make plain the organic unity that exists between the various parts of the subject, and to illustrate the wide applicability of ideas of analysis to other fields of mathematics and science. After

  12. Real-Life Stories About Addiction Struggles | NIH MedlinePlus the Magazine

    Science.gov (United States)

    ... on. Feature: Preventing Drug Abuse and Addiction Real-Life Stories About Addiction Struggles Past Issues / Fall 2011 ... TO PLAY THE VIDEO NIHSeniorHealth Videos Offer Real-Life Stories About Addiction Struggles—and Much More Many ...

  13. Control of asthma in real life: still a valuable goal?

    Directory of Open Access Journals (Sweden)

    Andriana I. Papaioannou

    2015-06-01

    Full Text Available Although studies show that control of asthma can be achieved in the majority of patients, surveys repeatedly show that this is not the case in real life. Important measures to implement in order to achieve asthma control are trained healthcare professionals, a good patient–doctor relationship, patient education, avoidance of exposure to triggers, personalised management and adherence to treatment. These measures help the majority of asthma patients but have not yet been widely implemented and there should be a concerted action for their implementation. Moreover, further and focused research is needed in severe/refractory asthma.

  14. Online Game Player Personality and Real-life Need Fulfillment

    Directory of Open Access Journals (Sweden)

    Ching-I Teng

    2009-12-01

    Full Text Available This study investigates the relationship between personality and real-life need fulfillment of 114 online game adolescent players, who had an average of 14.86 years in age and a standard deviation of 1.40 years. Of the sample, 73.7% were male and 88.8% had a monthly income below US $90. Results indicate that openness negatively correlated to fulfillment of needs for achievement and affiliation. Conscientiousness positively correlated to fulfillment of needs for achievement, affiliation, autonomy, and dominance. Extraversion positively correlated to fulfillment of needs for affiliation and dominance.

  15. Real-time hybrid simulation using the convolution integral method

    International Nuclear Information System (INIS)

    Kim, Sung Jig; Christenson, Richard E; Wojtkiewicz, Steven F; Johnson, Erik A

    2011-01-01

    This paper proposes a real-time hybrid simulation method that will allow complex systems to be tested within the hybrid test framework by employing the convolution integral (CI) method. The proposed CI method is potentially transformative for real-time hybrid simulation. The CI method can allow real-time hybrid simulation to be conducted regardless of the size and complexity of the numerical model and for numerical stability to be ensured in the presence of high frequency responses in the simulation. This paper presents the general theory behind the proposed CI method and provides experimental verification of the proposed method by comparing the CI method to the current integration time-stepping (ITS) method. Real-time hybrid simulation is conducted in the Advanced Hazard Mitigation Laboratory at the University of Connecticut. A seismically excited two-story shear frame building with a magneto-rheological (MR) fluid damper is selected as the test structure to experimentally validate the proposed method. The building structure is numerically modeled and simulated, while the MR damper is physically tested. Real-time hybrid simulation using the proposed CI method is shown to provide accurate results

  16. Virtual Worlds: Relationship between Real Life and Experience in Second Life

    Science.gov (United States)

    Anstadt, Scott P.; Bradley, Shannon; Burnette, Ashley; Medley, Lesley L.

    2013-01-01

    Due to the unique applications of virtual reality in many modern contexts, Second Life (SL) offers inimitable opportunities for research and exploration and experiential learning as part of a distance learning curriculum assignment. A review of current research regarding SL examined real world social influences in online interactions and what the…

  17. Integration of Real-Time Data Into Building Automation Systems

    Energy Technology Data Exchange (ETDEWEB)

    Mark J. Stunder; Perry Sebastian; Brenda A. Chube; Michael D. Koontz

    2003-04-16

    The project goal was to investigate the possibility of using predictive real-time information from the Internet as an input to building management system algorithms. The objectives were to identify the types of information most valuable to commercial and residential building owners, managers, and system designers. To comprehensively investigate and document currently available electronic real-time information suitable for use in building management systems. Verify the reliability of the information and recommend accreditation methods for data and providers. Assess methodologies to automatically retrieve and utilize the information. Characterize equipment required to implement automated integration. Demonstrate the feasibility and benefits of using the information in building management systems. Identify evolutionary control strategies.

  18. Integrated corporate structure life cycle management modeling and organization

    OpenAIRE

    Naumenko, M.; Morozova, L.

    2011-01-01

    Integrated business structure presented as complementary pool of its participants skills. The methodical approach to integrated business structure life cycle modeling proposed. Recommendations of enterprises life cycles stages correlate are submitted.

  19. The Integrative Business Experience: Real Choices and Real Consequences Create Real Thinking

    Science.gov (United States)

    McCord, Mary; Houseworth, Matthew; Michaelsen, Larry K.

    2015-01-01

    This article describes an innovation called the Integrative Business Experience (IBE) that links a set of required core business courses to an entrepreneurial practicum course in which two things occur. One is that students are concurrently enrolled in the required core business courses and a practicum course while they create a start-up business…

  20. Optimal Real-time Dispatch for Integrated Energy Systems

    DEFF Research Database (Denmark)

    Anvari-Moghaddam, Amjad; Guerrero, Josep M.; Rahimi-Kian, Ashkan

    2016-01-01

    With the emerging of small-scale integrated energy systems (IESs), there are significant potentials to increase the functionality of a typical demand-side management (DSM) strategy and typical implementation of building-level distributed energy resources (DERs). By integrating DSM and DERs...... into a cohesive, networked package that fully utilizes smart energy-efficient end-use devices, advanced building control/automation systems, and integrated communications architectures, it is possible to efficiently manage energy and comfort at the end-use location. In this paper, an ontology-driven multi......-agent control system with intelligent optimizers is proposed for optimal real-time dispatch of an integrated building and microgrid system considering coordinated demand response (DR) and DERs management. The optimal dispatch problem is formulated as a mixed integer nonlinear programing problem (MINLP...

  1. System Integration for Real-Time Mobile Manipulation

    Directory of Open Access Journals (Sweden)

    Reza Oftadeh

    2014-03-01

    Full Text Available Mobile manipulators are one of the most complicated types of mechatronics systems. The performance of these robots in performing complex manipulation tasks is highly correlated with the synchronization and integration of their low-level components. This paper discusses in detail the mechatronics design of a four wheel steered mobile manipulator. It presents the manipulator's mechanical structure and electrical interfaces, designs low-level software architecture based on embedded PC-based controls, and proposes a systematic solution based on code generation products of MATLAB and Simulink. The remote development environment described here is used to develop real-time controller software and modules for the mobile manipulator under a POSIX-compliant, real-time Linux operating system. Our approach enables developers to reliably design controller modules that meet the hard real-time constraints of the entire low-level system architecture. Moreover, it provides a systematic framework for the development and integration of hardware devices with various communication mediums and protocols, which facilitates the development and integration process of the software controller.

  2. Temporal compression in episodic memory for real-life events.

    Science.gov (United States)

    Jeunehomme, Olivier; Folville, Adrien; Stawarczyk, David; Van der Linden, Martial; D'Argembeau, Arnaud

    2018-07-01

    Remembering an event typically takes less time than experiencing it, suggesting that episodic memory represents past experience in a temporally compressed way. Little is known, however, about how the continuous flow of real-life events is summarised in memory. Here we investigated the nature and determinants of temporal compression by directly comparing memory contents with the objective timing of events as measured by a wearable camera. We found that episodic memories consist of a succession of moments of prior experience that represent events with varying compression rates, such that the density of retrieved information is modulated by goal processing and perceptual changes. Furthermore, the results showed that temporal compression rates remain relatively stable over one week and increase after a one-month delay, particularly for goal-related events. These data shed new light on temporal compression in episodic memory and suggest that compression rates are adaptively modulated to maintain current goal-relevant information.

  3. Integrated NPP life cycle management - Agency's approach

    International Nuclear Information System (INIS)

    Gueorguiev, B.

    2002-01-01

    Full text: The number of nuclear power plants (NPPs) operating in the world has been roughly constant for the past seven years. There are 438 reactors of 353,489 MW(e) capacity in the world and they generated 2448.9 TWh in 2001 giving a total world operating experience with nuclear power of 10,363 years. About 230 units have reached already over 15 years of operation and significant number of these plants are fully depreciated. Share of nuclear power in electricity production sector in Member States utilising nuclear power plants represents a meaningful amount and in 14 countries it exceeds 30%. Therefore, a loss of this share should be covered by new installed capacities either from conventional or alternative sources of electricity generation. Recent forecasts, for nuclear power use over the next two decades range from ∼350 to ∼500 GW(e) worldwide. While assessing the need for any nuclear power related programmes there are several important factors that must be considered since even 350 GW(e) is a very large programme requiring several hundred thousand highly qualified personnel and a substantial infrastructure to assure its continued safe, reliable and cost-effective operation. It is important to assure reliable, safe and economic beneficial performance of the plant, which requires in turn an appropriated management of any activity connected with any taken period of a plant life starting from design and ending by the decided mode of decommissioning. The period between the first and the last payment for the activities connected with the existence of a plant could be defined as a life cycle of the plant. Such integrated approach requires considering the life cycle of the plant in a much broader sense than just operational life and is characterized by the variety of activities and their management represents in a whole a plant life management programme (PLIM). Therefore PLIM could be defined as an aggregate (totality) of technical, financial, economical and

  4. Integration of virtual and real scenes within an integral 3D imaging environment

    Science.gov (United States)

    Ren, Jinsong; Aggoun, Amar; McCormick, Malcolm

    2002-11-01

    The Imaging Technologies group at De Montfort University has developed an integral 3D imaging system, which is seen as the most likely vehicle for 3D television avoiding psychological effects. To create real fascinating three-dimensional television programs, a virtual studio that performs the task of generating, editing and integrating the 3D contents involving virtual and real scenes is required. The paper presents, for the first time, the procedures, factors and methods of integrating computer-generated virtual scenes with real objects captured using the 3D integral imaging camera system. The method of computer generation of 3D integral images, where the lens array is modelled instead of the physical camera is described. In the model each micro-lens that captures different elemental images of the virtual scene is treated as an extended pinhole camera. An integration process named integrated rendering is illustrated. Detailed discussion and deep investigation are focused on depth extraction from captured integral 3D images. The depth calculation method from the disparity and the multiple baseline method that is used to improve the precision of depth estimation are also presented. The concept of colour SSD and its further improvement in the precision is proposed and verified.

  5. Measure and integral an introduction to real analysis

    CERN Document Server

    Wheeden, Richard L

    2015-01-01

    Now considered a classic text on the topic, Measure and Integral: An Introduction to Real Analysis provides an introduction to real analysis by first developing the theory of measure and integration in the simple setting of Euclidean space, and then presenting a more general treatment based on abstract notions characterized by axioms and with less geometric content.Published nearly forty years after the first edition, this long-awaited Second Edition also:Studies the Fourier transform of functions in the spaces L1, L2, and Lp, 1 p Shows the Hilbert transform to be a bounded operator on L2, as an application of the L2 theory of the Fourier transform in the one-dimensional caseCovers fractional integration and some topics related to mean oscillation properties of functions, such as the classes of Hölder continuous functions and the space of functions of bounded mean oscillationDerives a subrepresentation formula, which in higher dimensions plays a role roughly similar to the one played by the fundamental theor...

  6. Electric vehicle integration in a real-time market

    DEFF Research Database (Denmark)

    Pedersen, Anders Bro

    with an externally simulated model of the power grid, it is be possible, in real-time, to simulate the impact of EV charging and help to identify bottlenecks in the system. In EDISON the vehicles are aggregated using an entity called a Virtual Power Plant (VPP); a central server monitoring and controlling...... the distributed energy resources registered with it, in order to make them appear as a single producer in the eyes of the market. Although the concept of a VPP is used within the EcoGrid EU project, the idea of more individual control is introduced through a new proposed real-time electricity market, where......This project is rooted in the EDISON project, which dealt with Electrical Vehicle (EV) integration into the existing power grid, as well as with the infrastructure needed to facilitate the ever increasing penetration of fluctuating renewable energy resources like e.g. wind turbines. In the EDISON...

  7. Age differences in virtual environment and real world path integration

    Directory of Open Access Journals (Sweden)

    Diane E Adamo

    2012-09-01

    Full Text Available Accurate path integration requires the integration of visual, proprioceptive, and vestibular self-motion cues and age effects associated with alterations in processing information from these systems may contribute to declines in path integration abilities. The present study investigated age-related differences in path integration in conditions that varied as a function of available sources of sensory information. Twenty-two healthy, young (23.8 ± 3.0 yrs. and 16 older (70.1 ± 6.4 yrs. adults participated in distance reproduction and triangle completion tasks performed in a virtual environment and two real world conditions: guided walking and wheelchair propulsion. For walking and wheelchair propulsion conditions, participants wore a blindfold and wore noise-blocking headphones and were guided through the workspace by the experimenter. For the virtual environment (VE condition, participants viewed self-motion information on a computer monitor and used a joystick to navigate through the environment. For triangle completion tasks, older compared to younger individuals showed greater errors in rotation estimations performed in the wheelchair condition; and for rotation and distance estimations in the VE condition. Distance reproduction tasks, in contrast, did not show any age effects. These findings demonstrate that age differences in path integration vary as a function of the available sources of information and by the complexity of outbound pathway.

  8. "Real life" longevity of implantable cardioverter-defibrillator devices.

    Science.gov (United States)

    Manolis, Antonis S; Maounis, Themistoklis; Koulouris, Spyridon; Vassilikos, Vassilios

    2017-09-01

    Manufacturers of implantable cardioverter-defibrillators (ICDs) promise a 5- to 9-year projected longevity; however, real-life data indicate otherwise. The aim of the present study was to assess ICD longevity among 685 consecutive patients over the last 20 years. Real-life longevity of ICDs may differ from that stated by the manufacturers. The study included 601 men and 84 women (mean age, 63.1 ± 13.3 years). The underlying disease was coronary (n = 396) or valvular (n = 15) disease, cardiomyopathy (n = 220), or electrical disease (n = 54). The mean ejection fraction was 35%. Devices were implanted for secondary (n = 562) or primary (n = 123) prevention. Single- (n = 292) or dual-chamber (n = 269) or cardiac resynchronization therapy (CRT) devices (n = 124) were implanted in the abdomen (n = 17) or chest (n = 668). Over 20 years, ICD pulse generator replacements were performed in 238 patients (209 men; age 63.7 ± 13.9 years; ejection fraction, 37.7% ± 14.0%) who had an ICD for secondary (n = 210) or primary (n = 28) prevention. The mean ICD longevity was 58.3 ± 18.7 months. In 20 (8.4%) patients, devices exhibited premature battery depletion within 36 months. Most (94%) patients had none, minor, or modest use of ICD therapy. Longevity was longest for single-chamber devices and shortest for CRT devices. Latest-generation devices replaced over the second decade lasted longer compared with devices replaced during the first decade. When analyzed by manufacturer, Medtronic devices appeared to have longer longevity by 13 to 18 months. ICDs continue to have limited longevity of 4.9 ± 1.6 years, and 8% demonstrate premature battery depletion by 3 years. CRT devices have the shortest longevity (mean, 3.8 years) by 13 to 17 months, compared with other ICD devices. These findings have important implications, particularly in view of the high expense involved with this type of electrical

  9. Real-Life/Real-Time Elderly Fall Detection with a Triaxial Accelerometer.

    Science.gov (United States)

    Sucerquia, Angela; López, José David; Vargas-Bonilla, Jesús Francisco

    2018-04-05

    The consequences of a fall on an elderly person can be reduced if the accident is attended by medical personnel within the first hour. Independent elderly people often stay alone for long periods of time, being in more risk if they suffer a fall. The literature offers several approaches for detecting falls with embedded devices or smartphones using a triaxial accelerometer. Most of these approaches have not been tested with the target population or cannot be feasibly implemented in real-life conditions. In this work, we propose a fall detection methodology based on a non-linear classification feature and a Kalman filter with a periodicity detector to reduce the false positive rate. This methodology requires a sampling rate of only 25 Hz; it does not require large computations or memory and it is robust among devices. We tested our approach with the SisFall dataset achieving 99.4% of accuracy. We then validated it with a new round of simulated activities with young adults and an elderly person. Finally, we give the devices to three elderly persons for full-day validations. They continued with their normal life and the devices behaved as expected.

  10. Rehabilitation in the real-life environment of a shopping mall.

    Science.gov (United States)

    Labbé, Delphine; Poldma, Tiiu; Fichten, Catherine; Havel, Alice; Kehayia, Eva; Mazer, Barbara; McKinley, Patricia; Rochette, Annie; Swaine, Bonnie

    2018-04-01

    The aim of this study was to explore how shopping malls could be used during rehabilitation and to identify the facilitators and barriers to their use. Two focus groups, conducted with 15 rehabilitation professionals from various disciplines and working with people with disabilities of all ages were structured around two topics: (i) The usage of malls for rehabilitation and (ii) Factors that facilitate or limit rehabilitation professionals' use of the mall as an environment for clinical assessment and/or intervention. The thematic analysis revealed that shopping malls were used to achieve several rehabilitation goals targeting physical and cognitive skills, psychological health and socialization. This real-life environment is motivating and helps foster independence and normalization. Factors affecting mall use during rehabilitation included personal factors (e.g. clients' personality and level of readiness) and environmental factors (e.g. clinical context, accessibility of the mall and social attitudes of store owners). Shopping malls may be a relevant rehabilitation assessment and treatment environment that could contribute to optimizing community integration of people with disabilities. Implications for rehabilitation To ensure successful community reintegration, clients could be trained at some point during their rehabilitation, to perform activities in real-life settings, such as a shopping mall. Shopping malls appear to enable the attainment of rehabilitation goals targeting a variety of skills. This real-life environment appears to be motivating and helps foster independence and normalization. Factors felt to affect mall use during rehabilitation include personal factors (e.g. clients' personality and level of readiness) and environmental factors (e.g. clinical context, accessibility of the mall and social attitudes of store owners). The shopping mall may be an untapped resource as it appears to be a relevant rehabilitation assessment and treatment

  11. Integrative real-time geographic visualization of energy resources

    International Nuclear Information System (INIS)

    Sorokine, A.; Shankar, M.; Stovall, J.; Bhaduri, B.; King, T.; Fernandez, S.; Datar, N.; Omitaomu, O.

    2009-01-01

    'Full text:' Several models forecast that climatic changes will increase the frequency of disastrous events like droughts, hurricanes, and snow storms. Responding to these events and also to power outages caused by system errors such as the 2003 North American blackout require an interconnect-wide real-time monitoring system for various energy resources. Such a system should be capable of providing situational awareness to its users in the government and energy utilities by dynamically visualizing the status of the elements of the energy grid infrastructure and supply chain in geographic contexts. We demonstrate an approach that relies on Google Earth and similar standard-based platforms as client-side geographic viewers with a data-dependent server component. The users of the system can view status information in spatial and temporal contexts. These data can be integrated with a wide range of geographic sources including all standard Google Earth layers and a large number of energy and environmental data feeds. In addition, we show a real-time spatio-temporal data sharing capability across the users of the system, novel methods for visualizing dynamic network data, and a fine-grain access to very large multi-resolution geographic datasets for faster delivery of the data. The system can be extended to integrate contingency analysis results and other grid models to assess recovery and repair scenarios in the case of major disruption. (author)

  12. Safety and efficacy of venom immunotherapy: a real life study.

    Science.gov (United States)

    Kołaczek, Agnieszka; Skorupa, Dawid; Antczak-Marczak, Monika; Kuna, Piotr; Kupczyk, Maciej

    2017-04-01

    Venom immunotherapy (VIT) is recommended as the first-line treatment for patients allergic to Hymenoptera venom. To analyze the safety and efficacy of VIT in a real life setting. One hundred and eighty patients undergoing VIT were studied to evaluate the safety, efficacy, incidence and nature of symptoms after field stings and adverse reactions to VIT. Significantly more patients were allergic to wasp than bee venom (146 vs. 34, p bees, and were not associated with angiotensin convertase inhibitors (ACEi) or β-adrenergic antagonists use. Systemic reactions were observed in 4 individuals on wasp VIT (2.7%) and in 6 patients allergic to bees (17.65%). The VIT was efficacious as most patients reported no reactions (50%) or reported only mild local reactions (43.75%) to field stings. The decrease in sIgE at completion of VIT correlated with the dose of vaccine received ( r = 0.53, p = 0.004). Beekeeping (RR = 29.54, p venom allergy. Venom immunotherapy is highly efficacious and safe as most of the adverse events during the induction and maintenance phase are mild and local. Side effects of VIT are more common in subjects on bee VIT. Beekeeping and female sex are associated with a higher risk of allergy to Hymenoptera venom.

  13. Integrating Varieties of Life Course Concepts

    OpenAIRE

    Duane F. Alwin

    2012-01-01

    A body of work referred to as the "life course" framework (also known as "life course theory," the "life course paradigm," and the "life course perspective") has been increasingly used to motivate and justify the examination of the relationships among variables in social and behavioral science, particularly in the study of population health and aging. Yet, there is very little agreement on what some of these concepts mean, and there is hardly any agreement on what the "life course" is. This a...

  14. An integrated framework for SAGD real-time monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Mohajer, M.; Perez-Damas, C.; Berbin, A.; Al-kinani, A. [Schlumberger, Calgary, AB (Canada)

    2009-07-01

    This study examined the technologies and workflows for real-time optimization (RTO) of the steam assisted gravity drainage (SAGD) process. Although SAGD operators have tried to control the reservoir's steam chamber distribution to optimize bitumen recovery and minimize steam oil ratios, a true optimization can only be accomplished by implementing RTO workflows. In order for these workflows to be successful, some elements must be properly designed and introduced into the system. Most notably, well completions must ensure the integrity of downhole sensors; the appropriate measuring instruments must be selected; and surface and downhole measurements must be obtained. Operators have not been early adopters of RTO workflows for SAGD because of the numerous parameters that must be monitored, harsh operating conditions, the lack of integration between the different data acquisition systems, and the complex criteria required to optimize SAGD performance. This paper discussed the first stage in the development of a fully integrated RTO workflow for SAGD. An experimental apparatus with fiber optics distributed temperature sensing (DTS) was connected to a data acquisition system, and intra-minute data was streamed directly into an engineering desktop. The paper showed how subcool calculations can be effectively performed along the length of the horizontal well in real time and the results used to improve SAGD operation. Observations were compared against simulated predictions. In the next stage, a more complex set of criteria will be derived and additional data will be incorporated, such as surface heave, cross-well microseismic, multiphase flowmeter, and observation wells. 9 refs., 9 tabs., 13 figs.

  15. Map Matching and Real World Integrated Sensor Data Warehousing (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Burton, E.

    2014-02-01

    The inclusion of interlinked temporal and spatial elements within integrated sensor data enables a tremendous degree of flexibility when analyzing multi-component datasets. The presentation illustrates how to warehouse, process, and analyze high-resolution integrated sensor datasets to support complex system analysis at the entity and system levels. The example cases presented utilizes in-vehicle sensor system data to assess vehicle performance, while integrating a map matching algorithm to link vehicle data to roads to demonstrate the enhanced analysis possible via interlinking data elements. Furthermore, in addition to the flexibility provided, the examples presented illustrate concepts of maintaining proprietary operational information (Fleet DNA) and privacy of study participants (Transportation Secure Data Center) while producing widely distributed data products. Should real-time operational data be logged at high resolution across multiple infrastructure types, map matched to their associated infrastructure, and distributed employing a similar approach; dependencies between urban environment infrastructures components could be better understood. This understanding is especially crucial for the cities of the future where transportation will rely more on grid infrastructure to support its energy demands.

  16. Virtual Worlds: Relationship Between Real Life and Experience in Second Life

    Directory of Open Access Journals (Sweden)

    Scott P. Anstadt

    2013-09-01

    Full Text Available Due to the unique applications of virtual reality in many modern contexts, Second Life (SL offers inimitable opportunities for research and exploration and experiential learning as part of a distance learning curriculum assignment. A review of current research regarding SL examined real world social influences in online interactions and what the effects on users may be. This aids students in understanding the social constructionist perceptions and worldview of those persons they may serve in social services. This suggests the importance of developing an understanding of the relationship between users’ real life (RL and their SL. Some research has begun to reveal the effectiveness of telecommunication and computer simulation with certain clients in the fields of mental health and social work, yet there is a lack of sufficient research done within the context of virtual worlds. The current study surveyed users of several educationally and health focused SIMS (simulations as to what motivates their SL and RL interactions. The data explores associations between users’ RL and their SL in several areas,potentially addressing the future role of educating social work students regarding research methodology in online virtual reality interactions. Implications for social work are discussed including engaging clients using incentives for social participation built into the SL milieu.

  17. Integrated Approaches for the Study of Real Mineral Flotation Systems

    Directory of Open Access Journals (Sweden)

    Andrea Gerson

    2013-01-01

    Full Text Available It is more common than not, for mineral processing studies to proceed via the examination of model flotation systems with the resulting data often lacking statistical verification. The resultant concentrates and tails may then be subjected to a restricted range of analyses, for diagnosis of the flotation behavior variations observed, that themselves bias the outcomes. For instance surface analysis may be undertaken without reference to solution speciation, or liberation may be studied but surface speciation may not be taken into account. We propose an integrated approach whereby firstly the flotation data are vigorously scrutinized and the mineralogy, liberation, surface and solution speciation are examined in parallel to establish a chemical over view of the system. It is proposed that to make progress in the understanding of flotation systems, in terms of the minerals chemistry, that a multi-dimensional analytical approach is utilized and that the focus shifts towards the analysis of real ores and industrial flotation systems.

  18. Work and Life Integration: Faculty Balance in the Academy

    Science.gov (United States)

    Ehrens, Holly

    2016-01-01

    Faculty work life integration has evolved as an important area of research in the academic workplace. The evolution in thinking about faculty work life integration has progressively shifted focus from the problems of women and parents to research that considers both men and women, married and single, with or without children as participants in the…

  19. Non-Stop Lab Week: A Real Laboratory Experience for Life Sciences Postgraduate Courses

    Science.gov (United States)

    Freitas, Maria João; Silva, Joana Vieira; Korrodi-Gregório, Luís; Fardilha, Margarida

    2016-01-01

    At the Portuguese universities, practical classes of life sciences are usually professor-centered 2-hour classes. This approach results in students underprepared for a real work environment in a research/clinical laboratory. To provide students with a real-life laboratory environment, the Non-Stop Lab Week (NSLW) was created in the Molecular…

  20. Real life testing of a Hybrid PEM Fuel Cell Bus

    Science.gov (United States)

    Folkesson, Anders; Andersson, Christian; Alvfors, Per; Alaküla, Mats; Overgaard, Lars

    Fuel cells produce low quantities of local emissions, if any, and are therefore one of the most promising alternatives to internal combustion engines as the main power source in future vehicles. It is likely that urban buses will be among the first commercial applications for fuel cells in vehicles. This is due to the fact that urban buses are highly visible for the public, they contribute significantly to air pollution in urban areas, they have small limitations in weight and volume and fuelling is handled via a centralised infrastructure. Results and experiences from real life measurements of energy flows in a Scania Hybrid PEM Fuel Cell Concept Bus are presented in this paper. The tests consist of measurements during several standard duty cycles. The efficiency of the fuel cell system and of the complete vehicle are presented and discussed. The net efficiency of the fuel cell system was approximately 40% and the fuel consumption of the concept bus is between 42 and 48% lower compared to a standard Scania bus. Energy recovery by regenerative braking saves up 28% energy. Bus subsystems such as the pneumatic system for door opening, suspension and brakes, the hydraulic power steering, the 24 V grid, the water pump and the cooling fans consume approximately 7% of the energy in the fuel input or 17% of the net power output from the fuel cell system. The bus was built by a number of companies in a project partly financed by the European Commission's Joule programme. The comprehensive testing is partly financed by the Swedish programme "Den Gröna Bilen" (The Green Car). A 50 kW el fuel cell system is the power source and a high voltage battery pack works as an energy buffer and power booster. The fuel, compressed hydrogen, is stored in two high-pressure stainless steel vessels mounted on the roof of the bus. The bus has a series hybrid electric driveline with wheel hub motors with a maximum power of 100 kW. Hybrid Fuel Cell Buses have a big potential, but there are

  1. An integrated approach to plant life management

    International Nuclear Information System (INIS)

    Fredlund, L.

    1998-01-01

    Plant life is no longer determined by components, almost everything can be replaced. A plant life management program should aim at actions and replacements being performed at the right time. In order to manage this there is need for experience feedback systems, a plant specific risk study and safety upgrades. (author)

  2. Using XML technology for the ontology-based semantic integration of life science databases.

    Science.gov (United States)

    Philippi, Stephan; Köhler, Jacob

    2004-06-01

    Several hundred internet accessible life science databases with constantly growing contents and varying areas of specialization are publicly available via the internet. Database integration, consequently, is a fundamental prerequisite to be able to answer complex biological questions. Due to the presence of syntactic, schematic, and semantic heterogeneities, large scale database integration at present takes considerable efforts. As there is a growing apprehension of extensible markup language (XML) as a means for data exchange in the life sciences, this article focuses on the impact of XML technology on database integration in this area. In detail, a general architecture for ontology-driven data integration based on XML technology is introduced, which overcomes some of the traditional problems in this area. As a proof of concept, a prototypical implementation of this architecture based on a native XML database and an expert system shell is described for the realization of a real world integration scenario.

  3. Real life narratives enhance learning about the 'art and science' of midwifery practice.

    Science.gov (United States)

    Gilkison, Andrea; Giddings, Lynne; Smythe, Liz

    2016-03-01

    Health professional educators have long grappled with how to teach the more elusive art of practice alongside the science (a term that encompasses the sort of professional knowledge that can be directly passed on). A competent practitioner is one who knows when, how and for whom to apply knowledge and skills, thereby making the links between theory and practice. They combine art and science in such a way that integrates knowledge with insight. This participatory hermeneutic study explored the experience of teachers and students of implementing a narrative-centred curriculum in undergraduate midwifery education. It revealed that when real life narratives were central to the learning environment, students' learning about the art of midwifery practice was enhanced as they learned about midwifery decisions, reflected on their own values and beliefs and felt an emotional connection with the narrator. Further, art and science became melded together in the context specific wisdom of practice (phronesis).

  4. Real-life decision making in college students. I: Consistency across specific decisions.

    Science.gov (United States)

    Galotti, Kathleen M; Wiener, Hillary J D; Tandler, Jane M

    2014-01-01

    First-year undergraduates participated in a short-term longitudinal study of real-life decision making over their first 14 months of college. They were surveyed about 7 different decisions: choosing courses for an upcoming term (3 different terms), choosing an academic major (twice), planning for the upcoming summer, and planning for sophomore-year housing. Participants showed moderate levels of consistency in the options they considered and in the criteria they used to decide between options, with about half of the options or criteria being used at 2 different points on the decision repeatedly studied. Participants varied somewhat in structural consistency, the tendency to consider the same number of options or criteria across decisions. They also varied in the way they integrated information across decision-making tasks. We suggest that people attempt to keep the information demands of the task within workable limits, sometimes sacrificing consistency as a result.

  5. Managing in the Virtual World: How Second Life is Rewriting the Rules of "Real Life" Business

    Science.gov (United States)

    Wyld, David C.

    In this paper, we will explore the growth of virtual worlds - one of the most exciting and fast-growing concepts in the Web 2.0 era. We will see that while there has been significant growth across all demographic groups, online gaming in MMOGs (Massively Multiplayer Online Games) are finding particular appeal in today's youth - the so-called "digital native" generation. We then overview the today's virtual world marketplace, both in the youth and adult-oriented markets. Second Life is emerging as the most important virtual world today, due to the intense interest amongst both large organizations and individual entrepreneurs to conduct real business in the virtual environment. Due to its prominence today and its forecasted growth over the next decade, we take a look at the unscripted world of Second Life, examining the corporate presence in-world, as well as the economic, technical, legal, ethical and security issues involved for companies doing business in the virtual world. In conclusion, we present an analysis of where we stand in terms of virtual world development today and a projection of where we will be heading in the near future. Finally, we present advice to management practitioners and academicians on how to learn about virtual worlds and explore the world of opportunities in them.

  6. A real nonlinear integrable couplings of continuous soliton hierarchy and its Hamiltonian structure

    International Nuclear Information System (INIS)

    Yu Fajun

    2011-01-01

    Some integrable coupling systems of existing papers are linear integrable couplings. In the Letter, beginning with Lax pairs from special non-semisimple matrix Lie algebras, we establish a scheme for constructing real nonlinear integrable couplings of continuous soliton hierarchy. A direct application to the AKNS spectral problem leads to a novel nonlinear integrable couplings, then we consider the Hamiltonian structures of nonlinear integrable couplings of AKNS hierarchy with the component-trace identity. - Highlights: → We establish a scheme to construct real nonlinear integrable couplings. → We obtain a novel nonlinear integrable couplings of AKNS hierarchy. → Hamiltonian structure of nonlinear integrable couplings AKNS hierarchy is presented.

  7. Mathematics and Engineering in Real Life through Mathematical Competitions

    Science.gov (United States)

    More, M.

    2018-01-01

    We bring out an experience of organizing mathematical competitions that can be used as a medium to motivate the student and teacher minds in new directions of thinking. This can contribute to fostering research, innovation and provide a hands-on experience of mathematical concepts with the real world. Mathematical competitions can be used to build…

  8. Case study on Integral Life Practice intervention for physical ...

    African Journals Online (AJOL)

    Findings indicated significant improvements in physical exercise, psychophysiological coherence, general health, psychological well-being, mental skills, mindfulness, mood, resilience, sense of coherence and spirituality. Findings endorse Integral Life Practice theoretical principles and practical guidelines for implementing ...

  9. An Integrated Framework for Life Cycle Engineering

    DEFF Research Database (Denmark)

    Hauschild, Michael Zwicky; Herrmann, Christoph; Kara, Sami

    2017-01-01

    Life Cycle Engineering (LCE) was introduced as a concept more than 24 years ago in order to address emerging concerns about environmental sustainability in engineering. A number of methods and tools have been introduced to operationalise the LCE concept, but since then, the scope of sustainability...... has broadened, and as a result, LCE has evolved in parallel with other disciplines with similar aims. Currently, in addition to LCE, there exist a number of concepts such as Industrial Ecology, Cleaner Production, Life Cycle Management (LCM), Industrial Symbiosis, and Circular Economy. As a result......-down and bottom-up approach, the framework establishes a relationship between LCE and the other concepts and positions them relative to the planetary boundaries and the concept of absolute environmental sustainability. (C) 2017 The Authors. Published by Elsevier B.V....

  10. Learning based upon projects of architectural conservation: from university to real life

    OpenAIRE

    Mileto, Camilla; Vegas López-Manzanares, Fernando; Cristini, Valentina; Diodato, Maria

    2011-01-01

    Mileto, C.; Vegas López-Manzanares, F.; Cristini, V.; Diodato, M. (2011). Learning based upon projects of architectural conservation: from university to real life. IATED. 1-8. http://hdl.handle.net/10251/50072 Senia 1 8

  11. Effective Integration of Life Cycle Engineering in Education

    NARCIS (Netherlands)

    Oude Luttikhuis, Ellen; Toxopeus, Marten E.; Lutters, Diederick

    2015-01-01

    In practice, applying life cycle engineering in product design and development requires an integrated approach, because of the many stakeholders and variables (e.g. cost, environmental impact, energy, safety, quality) involved in a complete product life cycle. In educating young engineers, the same

  12. Social Anxiety in Online and Real-Life Interaction and Their Associated Factors

    OpenAIRE

    Yen, Ju-Yu; Yen, Cheng-Fang; Chen, Cheng-Sheng; Wang, Peng-Wei; Chang, Yi-Hsin; Ko, Chih-Hung

    2012-01-01

    Social anxiety was compared between online and real-life interaction in a sample of 2,348 college students. Severity of social anxiety in both real-life and online interaction was tested for associations with depression, Internet addiction, Internet activity type (gaming versus chatting), and scores on Behavioral Inhibition System (BIS)/Behavioral Activation System (BAS) scales. The results showed that social anxiety was lower when interacting online than when interacting offline. Depression,...

  13. Influence of an integral life practice workshop on health and ...

    African Journals Online (AJOL)

    The aim of the present investigation was to evaluate the effect of an Integral Life Practice workshop on perceptions of health and spirituality. An integral psychological approach using mixed quantitative and qualitative methods in a pre- and post-test, quasi experimental and control group design was used to assess changes ...

  14. A Real-Life Case Study of Audit Interactions--Resolving Messy, Complex Problems

    Science.gov (United States)

    Beattie, Vivien; Fearnley, Stella; Hines, Tony

    2012-01-01

    Real-life accounting and auditing problems are often complex and messy, requiring the synthesis of technical knowledge in addition to the application of generic skills. To help students acquire the necessary skills to deal with these problems effectively, educators have called for the use of case-based methods. Cases based on real situations (such…

  15. Feasibility of the integration of CRONOS, a 3-D neutronics code, into real-time simulators

    International Nuclear Information System (INIS)

    Ragusa, J.C.

    2001-01-01

    In its effort to contribute to nuclear power plant safety, CEA proposes the integration of an engineering grade 3-D neutronics code into a real-time plant analyser. This paper describes the capabilities of the neutronics code CRONOS to achieve a fast running performance. First, we will present current core models in simulators and explain their drawbacks. Secondly, the mean features of CRONOS's spatial-kinetics methods will be reviewed. We will then present an optimum core representation with respect to mesh size, choice of finite elements (FE) basis and execution time, for accurate results as well as the multi 1-D thermal-hydraulics (T/H) model developed to take into account 3-D effects in updating the cross-sections. A Main Steam Line Break (MSLB) End-of-Life (EOL) Hot-Zero-Power (HZP) accident will be used as an example, before we conclude with the perspectives of integrating CRONOS's 3-D core model into real-time simulators. (author)

  16. Feasibility of the integration of CRONOS, a 3-D neutronics code, into real-time simulators

    Energy Technology Data Exchange (ETDEWEB)

    Ragusa, J.C. [CEA Saclay, Dept. de Mecanique et de Technologie, 91 - Gif-sur-Yvette (France)

    2001-07-01

    In its effort to contribute to nuclear power plant safety, CEA proposes the integration of an engineering grade 3-D neutronics code into a real-time plant analyser. This paper describes the capabilities of the neutronics code CRONOS to achieve a fast running performance. First, we will present current core models in simulators and explain their drawbacks. Secondly, the mean features of CRONOS's spatial-kinetics methods will be reviewed. We will then present an optimum core representation with respect to mesh size, choice of finite elements (FE) basis and execution time, for accurate results as well as the multi 1-D thermal-hydraulics (T/H) model developed to take into account 3-D effects in updating the cross-sections. A Main Steam Line Break (MSLB) End-of-Life (EOL) Hot-Zero-Power (HZP) accident will be used as an example, before we conclude with the perspectives of integrating CRONOS's 3-D core model into real-time simulators. (author)

  17. Applications and real life spectra in the power generation industry

    International Nuclear Information System (INIS)

    Nix, K.J.; Lindley, T.C.

    1988-12-01

    Loading spectra encountered in various structures, machines, and components in the Power Generation Industry are presented from the viewpoint of fatigue analysis and structural integrity assessment. Although particular attention is paid to loading transients in turbo-generators, other items such as pressure vessels, pumped storage, nuclear plant pressure circuitry and wind turbines are also considered. (author)

  18. Communication patterns and satisfaction levels in three-dimensional versus real-life intimate relationships.

    Science.gov (United States)

    Gilbert, Richard L; Murphy, Nora A; Ávalos, M Clementina

    2011-10-01

    The present study compared communication patterns and satisfaction levels between three-dimensional (3D) and real-life intimate relationships using a sample of 71 participants who were concurrently involved in an intimate relationship within Second Life and a separate real-life romantic relationship. Participants indicated that the quality of their communication was significantly better in their Second-Life relationship and that they experienced higher levels of satisfaction with their virtual partners. The more positive or idealized view of the 3D relationships may have been due to higher levels of focused interaction and reduced stressors in the virtual world and the greater length, and associated problems, in participant's real-life relationships. In addition, the presence of a concurrent relationship within Second Life could have negatively affected participant's judgments of their real-life relationships. These data offer the first detailed assessment of communication patterns and satisfaction levels in intimate relationships across the real and 3D virtual realms as the number of users and romantic partners in immersive virtual environments continue to grow.

  19. Plant life management. Progress for structural integrity

    International Nuclear Information System (INIS)

    Solin, J.

    2003-03-01

    A joint project cluster of industry, VTT and other R and D suppliers is dealing with managing of lifetime of critical structures and components in energy and process industry. The research topics include systematic component lifetime management, data management, integrity and lifetime of pressure bearing components, non-destructive inspection, interactions of coolant and materials, environmentally assisted cracking and ageing of reactor internals. This Symposium is a compilation of selected papers describing an intermediate status of the projects after three years of research and development. (orig.)

  20. Registration accuracy and quality of real-life images.

    Directory of Open Access Journals (Sweden)

    Wei-Yen Hsu

    Full Text Available BACKGROUND: A common registration problem for the application of consumer device is to align all the acquired image sequences into a complete scene. Image alignment requires a registration algorithm that will compensate as much as possible for geometric variability among images. However, images captured views from a real scene usually produce different distortions. Some are derived from the optic characteristics of image sensors, and others are caused by the specific scenes and objects. METHODOLOGY/PRINCIPAL FINDINGS: An image registration algorithm considering the perspective projection is proposed for the application of consumer devices in this study. It exploits a multiresolution wavelet-based method to extract significant features. An analytic differential approach is then proposed to achieve fast convergence of point matching. Finally, the registration accuracy is further refined to obtain subpixel precision by a feature-based modified Levenberg-Marquardt method. Due to its feature-based and nonlinear characteristic, it converges considerably faster than most other methods. In addition, vignette compensation and color difference adjustment are also performed to further improve the quality of registration results. CONCLUSIONS/SIGNIFICANCE: The performance of the proposed method is evaluated by testing the synthetic and real images acquired by a hand-held digital still camera and in comparison with two registration techniques in terms of the squared sum of intensity differences (SSD and correlation coefficient (CC. The results indicate that the proposed method is promising in registration accuracy and quality, which are statistically significantly better than other two approaches.

  1. Optimal Real-time Dispatch for Integrated Energy Systems

    Energy Technology Data Exchange (ETDEWEB)

    Firestone, Ryan Michael [Univ. of California, Berkeley, CA (United States)

    2007-05-31

    This report describes the development and application of a dispatch optimization algorithm for integrated energy systems (IES) comprised of on-site cogeneration of heat and electricity, energy storage devices, and demand response opportunities. This work is intended to aid commercial and industrial sites in making use of modern computing power and optimization algorithms to make informed, near-optimal decisions under significant uncertainty and complex objective functions. The optimization algorithm uses a finite set of randomly generated future scenarios to approximate the true, stochastic future; constraints are included that prevent solutions to this approximate problem from deviating from solutions to the actual problem. The algorithm is then expressed as a mixed integer linear program, to which a powerful commercial solver is applied. A case study of United States Postal Service Processing and Distribution Centers (P&DC) in four cities and under three different electricity tariff structures is conducted to (1) determine the added value of optimal control to a cogeneration system over current, heuristic control strategies; (2) determine the value of limited electric load curtailment opportunities, with and without cogeneration; and (3) determine the trade-off between least-cost and least-carbon operations of a cogeneration system. Key results for the P&DC sites studied include (1) in locations where the average electricity and natural gas prices suggest a marginally profitable cogeneration system, optimal control can add up to 67% to the value of the cogeneration system; optimal control adds less value in locations where cogeneration is more clearly profitable; (2) optimal control under real-time pricing is (a) more complicated than under typical time-of-use tariffs and (b) at times necessary to make cogeneration economic at all; (3) limited electric load curtailment opportunities can be more valuable as a compliment to the cogeneration system than alone; and

  2. Bringing Reality into Calculus Classrooms: Mathematizing a Real-life Problem Simulated in a Virtual Environment

    Directory of Open Access Journals (Sweden)

    Olga V. Shipulina

    2013-01-01

    Full Text Available The study explores how students, who had completed the AP calculus course, mathematized the optimal navigation real-life problem simulated in the Second Life Virtual Environment. The particular research interest was to investigate whether/how students’ empirical activity in VE influences the way of their mathematizing.

  3. Real Life Calls for Real Books: Literature to Help Children Cope with Family Stressors

    Science.gov (United States)

    Roberts, Sherron Killingsworth; Crawford, Patricia A.

    2008-01-01

    This article provides a rationale and related practical suggestions for using literature as a support system for social-emotional development as children cope with the stresses, anxieties, and feelings of loss that can occur in family life. The authors discusses types of books, how to choose them, and how teachers can use authentic literature to…

  4. LOGIC SIMULATION OF LIFE SUPPORT SYSTEM COMPONENT IN REAL TIME

    Directory of Open Access Journals (Sweden)

    A. S. Marchenko

    2016-01-01

    Full Text Available Abstract. The article proposed the use of simulation methods for evaluating the effectiveness of a stepped fan engine speed control while maintaining the air flow volume in the set boundaries of the «fan-filter» system. A detailed algorithm of the program made on the basis of an Any Logic software package. Is analyzed the possibility of using the proposed method in the design of ventilation systems.The proposed method allows at the design stage to determine the maximum replacement intervals of the systems filter elements, as well as to predict the time to switch the fan motor speeds. Using of the technique allows to refuse the complex air flow systems and maximize the life of the filter elements set.Methods of logical processes modeling allows to reduce construction costs and improve energy efficiency of buildings. 

  5. Noninvasive Medical Tools for Evaluating Voiding Pattern in Real Life

    Directory of Open Access Journals (Sweden)

    Kwonsoo Chun

    2017-04-01

    Full Text Available Voiding dysfunction is a common disease that contributes to a lower quality of life and has an increased prevalence in the elderly population. Noninvasive and objective methods such as uroflowmetry (UFM and voiding diaries (VDs are essential for exact diagnosis and effective treatment of this condition because patients with different causes of voiding dysfunction can complain of the same lower urinary tract symptoms. Further, different treatment options can be determined based on the diagnosis made from these symptoms. In order to improve the quality of UFM and VDs and to provide a convenient testing environment, several advances have been made by previous investigators. In this study, we investigate the history and technological mechanisms of UFM and VDs. We also aim to review UFM from the viewpoint of clinical and at-home uses, including the recently proposed toilet-shaped UFM and electronic VDs.

  6. Biometric identification devices -- Laboratory testing vs. real life

    International Nuclear Information System (INIS)

    Ahrens, J.S.

    1997-01-01

    For over fifteen years Sandia National Laboratories has been involved in laboratory testing of biometric identification devices. The key concept of biometric identification devices is the ability for the system to identify some unique aspect of the individual rather than some object a person may be carrying or some password they are required to know. Tests were conducted to verify manufacturer's performance claims, to determine strengths/weaknesses of devices, and to determine devices that meet the US Department of energy's needs. However, during recent field installation, significantly different performance was observed than was predicted by laboratory tests. Although most people using the device believed it operated adequately, the performance observed was over an order of magnitude worse than predicted. The search for reasons behind this gap between the predicted and the actual performance has revealed many possible contributing factors. As engineers, the most valuable lesson to be learned from this experience is the value of scientists and engineers with (1) common sense, (2) knowledge of human behavior, (3) the ability to observe the real world, and (4) the capability to realize the significant differences between controlled experiments and actual installations

  7. Integrated Data Management for Mobile Services in the Real World

    DEFF Research Database (Denmark)

    Hage, C.; Jensen, Christian Søndergaard; Pedersen, Torben Bach

    2003-01-01

    Market research companies predict a huge market for services to be delivered to mobile users. Services in5 clude route guidance, point-of-interest search, metering services such as road pricing and parking payment, traffic monitoring, etc. We believe that no single such service will be the killer...... service, but that suites of integrated services are called for. Such integrated services reuse integrated content obtained from multiple content providers. This paper describes concepts and techniques underlying the data management system deployed by a Danish mobile content integrator. While geo...

  8. Torsional Topological Invariants (and their relevance for real life)

    CERN Document Server

    Chandia, O; Chandia, Osvaldo; Zanelli, Jorge

    1997-01-01

    The existence of topological invariants analogous to Chern/Pontryagin classes for a standard $SO(D)$ or SU(N) connection, but constructed out of the torsion tensor, is discussed. These invariants exhibit many of the features of the Chern/Pontryagin invariants: they can be expressed as integrals over the manifold of local densities and take integer values on compact spaces without boundary; their spectrum is determined by the homotopy groups determined by the connection bundle but depend also on the bundle of local orthonormal frames on the tangent space of the manifold. It is shown that in spacetimes with nonvanishing torsion there can occur topologically stable configurations associated with the frame bundle which are independent of the curvature. Explicit examples of topologically stable configurations carrying nonvanishing instanton number in four and eight dimensions are given, and they can be conjectured to exist in dimension $4k$. It is also shown that the chiral anomaly in a spacetime with torsion rece...

  9. Real-Time Integrated Re-scheduling for Tramway Operations

    NARCIS (Netherlands)

    Cheung, Kam-Fung; Kuo, Yong-Hong; Lai, S.W.; Leung, Janny M.Y.

    2018-01-01

    Our work aims to develop practical solution approaches for real-time dispatch of crews and vehicles for disruption management. The practical motivation for our research arose from the operations of a public tramway system in Hong Kong. The tram system shares the road with other vehicular traffic in

  10. Representing real time semantics for distributed application integration

    NARCIS (Netherlands)

    Poon, P.M.S.; Dillon, T.S.; Chang, E.; Feng, L.

    Traditional real time system design and development are driven by technological requirements. With the ever growing complexity of requirements and the advances in software design, the alignment of focus has gradually been shifted to the perspective of business and industrial needs. This paper

  11. Cervical and facial infections - a real life threat

    Science.gov (United States)

    Rosu, S.; Fratila, M.

    2014-03-01

    Cervicofacial infections of dental origin are a difficult and complex issue of oral and maxillofacial surgery. Recognizing in due time the situations which are likely to develop a life-threatening condition and medical surgical prompt interventions significantly reduce the rate of the complications. Between January 2009 and March 2013, at the Clinic of Oral and Maxillofacial Surgery of the University of Medicine and Pharmacy "Victor Babes" Timisoara, 17 patients with severe cervicofacial infections were admitted in the emergency department as they needed a complex medical surgical treatment in accordance with protocol established together with the intensive-care department. Assessing the situations, we noticed a difficult, prolonged time of the recovery process which needed a hospitalization period of around 20 days. It recorded two deceased because of cervical necrotizing fasciitis and oral floor phlegmon, the most severe forms of the cervicofacial infections. The severity of the condition of the patients with cervicofacial infections must be figured and as quickly as possible an energetic therapeutic attitude must be adopted. The experience shows a frequent resistance to antibiotics like ampicillin, penicillin and oxacillin. The patients must be guided in due time to a clinic which has an intensive care department, where the surgical treatment must be administrated together with an intensive treatment for supporting the general condition. The reduction of the vital risk of the cervicofacial infections of dental origin will be done through an attentive assessment of the general and local condition (status) of the outpatients, before the dental extraction. The absence of a treatment adapted to the situation and to the clinic development, meaningfully increases the rate of the complications and the length of the hospitalization, the lethal evolution being not excluded.

  12. Cervical and facial infections – a real life threat

    International Nuclear Information System (INIS)

    Victor Babeş Timişoara, Piaţa Eftimie Murgu No. 2, 300041 (Romania))" data-affiliation=" (Maxillo-facial surgeon University of Medicine and Pharmacy Victor Babeş Timişoara, Piaţa Eftimie Murgu No. 2, 300041 (Romania))" >Rosu, S; Victor Babeş Timişoara, Piaţa Eftimie Murgu No. 2, 300041 (Romania))" data-affiliation=" (Maxillo-facial surgeon University of Medicine and Pharmacy Victor Babeş Timişoara, Piaţa Eftimie Murgu No. 2, 300041 (Romania))" >Fratila, M

    2014-01-01

    Cervicofacial infections of dental origin are a difficult and complex issue of oral and maxillofacial surgery. Recognizing in due time the situations which are likely to develop a life-threatening condition and medical surgical prompt interventions significantly reduce the rate of the complications. Between January 2009 and March 2013, at the Clinic of Oral and Maxillofacial Surgery of the University of Medicine and Pharmacy ''Victor Babes'' Timisoara, 17 patients with severe cervicofacial infections were admitted in the emergency department as they needed a complex medical surgical treatment in accordance with protocol established together with the intensive-care department. Assessing the situations, we noticed a difficult, prolonged time of the recovery process which needed a hospitalization period of around 20 days. It recorded two deceased because of cervical necrotizing fasciitis and oral floor phlegmon, the most severe forms of the cervicofacial infections. The severity of the condition of the patients with cervicofacial infections must be figured and as quickly as possible an energetic therapeutic attitude must be adopted. The experience shows a frequent resistance to antibiotics like ampicillin, penicillin and oxacillin. The patients must be guided in due time to a clinic which has an intensive care department, where the surgical treatment must be administrated together with an intensive treatment for supporting the general condition. The reduction of the vital risk of the cervicofacial infections of dental origin will be done through an attentive assessment of the general and local condition (status) of the outpatients, before the dental extraction. The absence of a treatment adapted to the situation and to the clinic development, meaningfully increases the rate of the complications and the length of the hospitalization, the lethal evolution being not excluded

  13. Solid oxide fuel cells towards real life applications. Final report

    Energy Technology Data Exchange (ETDEWEB)

    2010-07-01

    Solid Oxide Fuel Cells offer a clean and efficient way of producing electricity and heat from a wide selection of fuels. The project addressed three major challenges to be overcome by the technology to make commercialisation possible. (1) At the cell level, increased efficiency combined with production cost reduction has been achieved through an optimization of the manufacturing processes, b) by using alternative raw materials with a lower purchase price and c) by introducing a new generation of fuel cells with reduced loss and higher efficiency. (2) At the stack level, production cost reduction is reduced and manufacturing capacity is increased through an optimization of the stack production. (3) At the system level, development of integrated hotbox concepts for the market segments distributed generation (DG), micro combined heat and power (mCHP), and auxiliary power units (APU) have been developed. In the mCHP segment, two concepts have been developed and validated with regards to market requirements and scalability. In the APU-segment, different types of reformers have been tested and it has been proven that diesel can be reformed through appropriate reformers. Finally, operation experience and feedback has been gained by deployment of stacks in the test facility at the H.C. OErsted Power Plant (HCV). This demonstration has been carried out in collaboration between TOFC and DONG Energy Power A/S (DONG), who has participated as a subcontractor to TOFC. The demonstration has given valuable knowledge and experience with design, start-up and operation of small power units connected to the grid and future development within especially the mCHP segment will benefit from this. In this report, the project results are described for each of the work packages in the project. (Author)

  14. In Patients with Cirrhosis, Driving Simulator Performance is Associated With Real-life Driving

    DEFF Research Database (Denmark)

    Lauridsen, Mette Enok Munk; Thacker, Leroy R; White, Melanie B

    2016-01-01

    BACKGROUND & AIMS: Minimal hepatic encephalopathy (MHE) has been linked to higher real-life rates of automobile crashes and poor performance in driving simulation studies, but the link between driving simulator performance and real-life automobile crashes has not been clearly established. Further......, not all patients with MHE are unsafe drivers, but it is unclear how to distinguish them from unsafe drivers. We investigated the link between performance on driving simulators and real-life automobile accidents and traffic violations. We also aimed to identify features of unsafe drivers with cirrhosis...... and evaluated changes in simulated driving skills and MHE status after 1 year. METHODS: We performed a study of outpatients with cirrhosis (n=205; median 55 years old; median model for end-stage liver disease score, 9.5; none with overt hepatic encephalopathy or alcohol or illicit drug use within previous 6...

  15. High correlation between performance on a virtual-reality simulator and real-life cataract surgery

    DEFF Research Database (Denmark)

    Thomsen, Ann Sofia Skou; Smith, Phillip; Subhi, Yousif

    2017-01-01

    -tracking software of cataract surgical videos with a Pearson correlation coefficient of -0.70 (p = 0.017). CONCLUSION: Performance on the EyeSi simulator is significantly and highly correlated to real-life surgical performance. However, it is recommended that performance assessments are made using multiple data......PURPOSE: To investigate the correlation in performance of cataract surgery between a virtual-reality simulator and real-life surgery using two objective assessment tools with evidence of validity. METHODS: Cataract surgeons with varying levels of experience were included in the study. All...... antitremor training, forceps training, bimanual training, capsulorhexis and phaco divide and conquer. RESULTS: Eleven surgeons were enrolled. After a designated warm-up period, the proficiency-based test on the EyeSi simulator was strongly correlated to real-life performance measured by motion...

  16. A method for strategic technical life cycle management of real estates

    OpenAIRE

    Koskelo, Taina

    2005-01-01

    This research study focuses on the strategic technical life cycle management (TLCM) of real estate. In the early phases of the study it became clear that very often the performance of TLCM was not perceived as satisfactory: there were problems in the purchasing and provision of technical services, TLCM was not performed according to real estate specific needs and objective-setting for building characteristics did not serve cost-effective ownership. The study focuses on four research quest...

  17. Integrating Security in Real-Time Embedded Systems

    Science.gov (United States)

    2017-04-26

    Operations and Reports (0704-0188), 1215 Jefferson Davis Highway, Suite 1204, Arl ington, VA 22202-4302. Respondents should be aware that... operate without impacting the tinting and safety constraints of the control logic. Besides, the embedded nature of these systems limits the...only during slack times when no other real-time tasks are rwming. We propose to measure the security of the system by means of the achievable periodic

  18. Emotional and Physiological Desensitization to Real-Life and Movie Violence

    Science.gov (United States)

    Mrug, Sylvie; Madan, Anjana; Cook, Edwin W.; Wright, Rex A.

    2014-01-01

    Youth are exposed to large amounts of violence in real life and media, which may lead to desensitization. Given evidence of curvilinear associations between exposure to violence and emotional distress, we examined linear and curvilinear associations of exposure to real-life and movie violence with PTSD symptoms, empathy, and physiological arousal, as well emotional and physiological reactivity to movie violence. College students (N=209; mean age=18.74) reported on their exposure to real-life and televised violence, PTSD symptoms, and empathy. Then, students were randomly assigned to view a series of violent or nonviolent high-action movie scenes, providing ratings of emotional distress after each clip. Blood pressure was measured at rest and during video viewing. Results showed that with increasing exposure to real-life violence, youth reported more PTSD symptoms and greater identification with fictional characters. Cognitive and emotional empathy increased from low to medium levels of exposure to violence, but declined at higher levels. For males, exposure to higher levels of real-life violence was associated with diminishing (vs. increasing) emotional distress when viewing violent videos. Exposure to televised violence was generally unrelated to emotional functioning. However, those with medium levels of exposure to TV/movie violence experienced lower elevations of blood pressure when viewing violent videos compared to those with low exposure, and those with higher levels of exposure evidenced rapid increase in blood pressure that quickly declined over time. The results point to diminished empathy and reduced emotional reactivity to violence as key aspects of desensitization to real-life violence, and more limited evidence of physiological desensitization to movie violence among those exposed to high levels of televised violence. PMID:25326900

  19. How Accumulated Real Life Stress Experience and Cognitive Speed Interact on Decision-Making Processes.

    Science.gov (United States)

    Friedel, Eva; Sebold, Miriam; Kuitunen-Paul, Sören; Nebe, Stephan; Veer, Ilya M; Zimmermann, Ulrich S; Schlagenhauf, Florian; Smolka, Michael N; Rapp, Michael; Walter, Henrik; Heinz, Andreas

    2017-01-01

    Rationale: Advances in neurocomputational modeling suggest that valuation systems for goal-directed (deliberative) on one side, and habitual (automatic) decision-making on the other side may rely on distinct computational strategies for reinforcement learning, namely model-free vs. model-based learning. As a key theoretical difference, the model-based system strongly demands cognitive functions to plan actions prospectively based on an internal cognitive model of the environment, whereas valuation in the model-free system relies on rather simple learning rules from operant conditioning to retrospectively associate actions with their outcomes and is thus cognitively less demanding. Acute stress reactivity is known to impair model-based but not model-free choice behavior, with higher working memory capacity protecting the model-based system from acute stress. However, it is not clear which impact accumulated real life stress has on model-free and model-based decision systems and how this influence interacts with cognitive abilities. Methods: We used a sequential decision-making task distinguishing relative contributions of both learning strategies to choice behavior, the Social Readjustment Rating Scale questionnaire to assess accumulated real life stress, and the Digit Symbol Substitution Test to test cognitive speed in 95 healthy subjects. Results: Individuals reporting high stress exposure who had low cognitive speed showed reduced model-based but increased model-free behavioral control. In contrast, subjects exposed to accumulated real life stress with high cognitive speed displayed increased model-based performance but reduced model-free control. Conclusion: These findings suggest that accumulated real life stress exposure can enhance reliance on cognitive speed for model-based computations, which may ultimately protect the model-based system from the detrimental influences of accumulated real life stress. The combination of accumulated real life stress exposure

  20. Acoustic Coordinated Reset Neuromodulation in a Real Life Patient Population with Chronic Tonal Tinnitus

    Science.gov (United States)

    Hauptmann, Christian; Ströbel, Armin; Williams, Mark; Patel, Nitesh; Wurzer, Hannes; von Stackelberg, Tatjana; Brinkmann, Uwe; Langguth, Berthold; Tass, Peter A.

    2015-01-01

    Purpose. Primary tinnitus has a severe negative influence on the quality of life of a significant portion of the general population. Acoustic coordinated reset neuromodulation is designed to induce a long-lasting reduction of tinnitus symptoms. To test acoustic coordinated reset neuromodulation as a treatment for chronic, tonal tinnitus under real life conditions, an outpatient study “RESET Real Life” was commissioned by ANM GmbH. Herein we present the results of this study. Methods. In a prospective, open-label, nonrandomized, noncontrolled multicenter clinical study with 200 chronic tinnitus patients, tinnitus questionnaire TBF-12 and Global Clinical Improvement-Impression Scale (CGI-I7) are used to study the safety and efficacy of acoustic coordinated reset neuromodulation. 189 patients completed the last 12-month visit, 11 patients dropped out (8 because of nontreatment related reasons; 2 because tinnitus did not change; and 1 because tinnitus got louder). Results. Acoustic coordinated reset neuromodulation caused a statistically and clinically significant decrease in TBF-12 scores as well as in CGI-I7 after 12 months of therapy under real life conditions. There were no persistent adverse events reported that were related to the therapy. Conclusion. The field study “RESET Real Life” provides evidence for safety and efficacy of acoustic coordinated reset neuromodulation in a prospective, open-label, real life setting. PMID:26568958

  1. Meaning in life of older persons : An integrative literature review

    NARCIS (Netherlands)

    MSc S.H.A. Hupkens; Anja Machielse; Dr. M.J.B.M. Goumans; P. Derkx

    2016-01-01

    The aim of this integrative review for nurses is to synthesize knowledge from scholarly literature to provide insight into how older persons find meaning in life, what are influencing circumstances, and what are their sources of meaning. The review serves as a starting point for including meaning in

  2. How Do Volcanoes Affect Human Life? Integrated Unit.

    Science.gov (United States)

    Dayton, Rebecca; Edwards, Carrie; Sisler, Michelle

    This packet contains a unit on teaching about volcanoes. The following question is addressed: How do volcanoes affect human life? The unit covers approximately three weeks of instruction and strives to present volcanoes in an holistic form. The five subject areas of art, language arts, mathematics, science, and social studies are integrated into…

  3. System Integration and Its Influence on the Quality of Life of Children with Complex Needs

    Directory of Open Access Journals (Sweden)

    Sandy Thurston

    2010-01-01

    Full Text Available Purpose. To explore the interactions between child and parents psychosocial factors and team integration variables that may explain improvements in physical dimensions of the PEDS QL quality of life of children with complex needs after 2 years. Methods. In this 2-year study, parents were identified by the Children's Treatment Network. Families were eligible if the child was aged 0–19 years, had physical limitations, resided in either Simcoe County or the Region of York, Ontario, and there were multiple other family needs. Regression analysis used to explore associations and interactions; n=110. Results. A child's physical quality of life was affected by interacting factors including child's behavior, parenting, and integrated care. Statistically significant interactions between team integration, processes of care, and child/parent variables highlight the complexity of the rehabilitation approach in real-life situations. Conclusions. Rehabilitation providers working with children with complex needs and their families should also address child and parent problematic behaviors. When this was the case in high integrated teams, the child's physical quality of life improved after two years.

  4. Efficient and Flexible KNN Query Processing in Real-Life Road Networks

    DEFF Research Database (Denmark)

    Lu, Yang; Bui, Bin; Zhao, Jiakui

    2008-01-01

    are included into the RNG index, which enables the index to support both distance-based and time-based KNN queries and continuous KNN queries. Our work extends previous ones by taking into account more practical scenarios, such as complexities in real-life road networks and time-based KNN queries. Extensive......Along with the developments of mobile services, effectively modeling road networks and efficiently indexing and querying network constrained objects has become a challenging problem. In this paper, we first introduce a road network model which captures real-life road networks better than previous...

  5. Ultrasonic wave propagation in real-life austenitic V-butt welds: Numerical modeling and validation

    International Nuclear Information System (INIS)

    Hannemann, R.; Marklein, R.; Langenberg, K. J.; Schurig, C.; Koehler, B.; Walte, F.

    2000-01-01

    In nondestructive testing the evaluation of austenitic steel welds with ultrasound is a commonly used method. But, since the wave propagation, scattering, and diffraction effects in such complicated media are hardly understood, computer simulations are very helpful to increase the knowledge of the physical phenomena in such samples. A particularly powerful numerical time domain modeling tool is the well established Elastodynamic Finite Integration Technique (EFIT). Recently, EFIT has been extended to simulate elastic waves in inhomogeneous anisotropic media. In this paper, the step-by-step evaluation of ultrasonic wave propagation in inhomogeneous anisotropic media will be described and the results will be validated against measurements. As a simplified model, a V-butt weld with perpendicular grain structure is investigated. The coincidence between the B Scans of the simulation and the measurement of an idealized V-butt weld is remarkable and even effects predicted by theory and simulation - the appearance of two coupled quasi-SV waves - can be observed. As a next step, an improved and more realistic model of the grain orientation inside the V-butt weld is introduced. This model has been implemented in the EFIT code and has been validated against measurements. For this verification, measured and simulated B-Scans for a real-life V-butt weld have been compared and a significant coincidence has been observed. Furthermore, the main pulses in the B-Scans are interpreted by analyzing the snapshot-movies of the wavefronts

  6. Real-life decision making in college students. II: Do individual differences show reliable effects?

    Science.gov (United States)

    Galotti, Kathleen M; Tandler, Jane M; Wiener, Hillary J D

    2014-01-01

    First-year undergraduates participated in a short-term longitudinal study of real-life decision making over their first 14 months of college. They were surveyed about 7 different decisions: choosing courses for upcoming terms (on 3 different occasions), choosing an academic major (twice), planning for the upcoming summer, and planning for sophomore-year housing. They also completed a survey of self-reported decision-making styles and the Need for Cognition survey (Cacioppo & Petty, 1982) to assess their focus on rationality and enjoyment of analytic thinking. Results showed few statistically significant correlations between stylistic measures and behavioral measures of decision making, in either the amount of information considered or the way in which the information integration tracked predictions of linear models of decision making applied to each participant's data. However, there were consistent correlations, across the 7 decisions, between stylistic measures and affective reactions to, or retrospective descriptions of, episodes of decision making. We suggest that decision-making styles instruments may better reflect the construction of narratives of self as a decision maker more than they do actual behavior during decision making.

  7. Analysis of integrated plant upgrading/life extension programs

    International Nuclear Information System (INIS)

    McCutchan, D.A.; Massie, H.W. Jr.; McFetridge, R.H.

    1988-01-01

    A present-worth generating cost model has been developed and used to evaluate the economic value of integrated plant upgrading life extension project in nuclear power plants. This paper shows that integrated plant upgrading programs can be developed in which a mix of near-term availability, power rating, and heat rate improvements can be obtained in combination with life extension. All significant benefits and costs are evaluated from the viewpoint of the utility, as measured in discounted revenue requirement differentials between alternative plans which are equivalent in system generating capacity. The near-term upgrading benefits are shown to enhance the benefit picture substantially. In some cases the net benefit is positive, even if the actual life extension proves to be less than expected

  8. Assessing the Value of Real-life Brands in Virtual Worlds

    DEFF Research Database (Denmark)

    Mattsson, Jan; Barnes, Stuart; Hartley, Nicole

    2015-01-01

    World. A key finding is the difficulty in creating emotional brand value in Second Life which has serious implications for the sustainability of current real-life brands in Virtual Worlds. The paper rounds off with conclusions and implications for future research and practice in this very new area.......Virtual Worlds are a significant new market environment for brand-building through experiential customer service interactions. Using value theory, this paper aims to assess the experiential brand value of real-life brands that have moved to the Virtual World of Second Life. A key premise...... is that current brand offerings in Virtual Worlds do not offer consumers adequate experiential value. The results demonstrate both the validity of an axiological approach to examining brand value, and highlight significant problems in consumer perceptions of the experiential value of brands within the Virtual...

  9. Integrated systems for real time data acquisition and processing

    International Nuclear Information System (INIS)

    Oprea, I.; Oprea, M.

    1995-01-01

    The continuous measuring of all the nuclear and dosimetric parameters in a nuclear facility is essential for personnel and environment protection. Considering the vast amount of information and data required to keep an updated overview of a situation the need for an efficient acquisition processing and information system is evident. The paper analyses the special requirements as concerning the real time inter-process communication and proposes a modern concept based on the last trends existing in the field of computer technology and operating systems. (author)

  10. Community Integration and Quality of Life in Aphasia after Stroke.

    Science.gov (United States)

    Lee, Hyejin; Lee, Yuna; Choi, Hyunsoo; Pyun, Sung-Bom

    2015-11-01

    To examine community integration and contributing factors in people with aphasia (PWA) following stroke and to investigate the relationship between community integration and quality of life (QOL). Thirty PWA and 42 age-and education-matched control subjects were involved. Main variables were as follows: socioeconomic status, mobility, and activity of daily living (ADL) (Modified Barthel Index), language function [Frenchay Aphasia Screening Test (FAST)], depression [Geriatric Depression Scale (GDS)], Community Integration Questionnaire (CIQ) and Stroke and Aphasia Quality of Life Scale-39 (SAQOL-39). Differences between aphasia and control groups and factors affecting community integration and QOL were analyzed. Home and social integration and productive activity were significantly decreased in the aphasia group compared to the control group; 8.5 and 18.3 points in total CIQ score, respectively. Amount of time spent outside the home and frequency of social contact were also significantly reduced in the aphasia group. Total mean score on the SAQOL-39 was 2.75±0.80 points and was significantly correlated with economic status, gait performance, ADL, depressive mood, and social domain score on the CIQ. Depression score measured by GDS was the single most important factor for the prediction of QOL, but the FAST score was significantly correlated only with the communication domain of the SAQOL-39. Community activities of PWA were very limited, and depression was highly associated with decreased community integration and QOL. Enhancing social participation and reducing emotional distress should be emphasized for rehabilitation of PWA.

  11. System Engineering and Integration of Controls for Advanced Life Support

    Science.gov (United States)

    Overland, David; Hoo, Karlene; Ciskowski, Marvin

    2006-01-01

    The Advanced Integration Matrix (AIM) project at the Johnson Space Center (JSC) was chartered to study and solve systems-level integration issues for exploration missions. One of the first issues identified was an inability to conduct trade studies on control system architectures due to the absence of mature evaluation criteria. Such architectures are necessary to enable integration of regenerative life support systems. A team was formed to address issues concerning software and hardware architectures and system controls.. The team has investigated what is required to integrate controls for the types of non-linear dynamic systems encountered in advanced life support. To this end, a water processing bioreactor testbed is being developed which will enable prototyping and testing of integration strategies and technologies. Although systems such as the water bioreactors exhibit the complexities of interactions between control schemes most vividly, it is apparent that this behavior and its attendant risks will manifest itself among any set of interdependent autonomous control systems. A methodology for developing integration requirements for interdependent and autonomous systems is a goal of this team and this testbed. This paper is a high-level summary of the current status of the investigation, the issues encountered, some tentative conclusions, and the direction expected for further research.

  12. Quality of Life in People with Leg Ulcer, Integrative Review

    Directory of Open Access Journals (Sweden)

    Daniela Alves

    2016-04-01

    Full Text Available Objective: To identify the main changes in the daily life of people with leg ulcer and how that affects the person’s quality of life. Methodology: We used the methodology PI [C] OD and selected four research articles, taken from EBSCO, PubMed, and EWMA. Results: The main changes identified in the people’s daily live with leg ulcers are physical (pain, decreased mobility, presence of exudate, bad smell from the wound and change in the style of clothing, psychological (sleep disorders, depression, anxiety, feelings of rejection and low self-steem, social (isolation, restriction in leisure activities, inability to perform household chores. Conclusions: The literature about the person’s quality of life with leg ulcer reported a significant impact in the daily life. The care provided by nurses should be centered on the person, integrating all the kind of needs and the leg ulcer must not be the sole focus of care

  13. System Integration for Real-time Mobile Manipulation

    OpenAIRE

    Oftadeh, Reza; Aref, Mohammad M.; Ghabcheloo, Reza; Mattila, Jouni

    2014-01-01

    Mobile manipulators are one of the most complicated types of mechatronics systems. The performance of these robots in performing complex manipulation tasks is highly correlated with the synchronization and integration of their low-level components. This paper discusses in detail the mechatronics design of a four wheel steered mobile manipulator. It presents the manipulator ’s mechanical structure and electrical interfaces, designs low-level software architecture based on embedded PC-based con...

  14. Working as simulated patient has effects on real patient life – Preliminary insights from a qualitative study

    Directory of Open Access Journals (Sweden)

    Simmenroth-Nayda, Anne

    2016-05-01

    Full Text Available Background: Persons who simulate patients during medical education understand the routines and the underlying script of medical consultations better. We aimed to explore how simulated patients (SPs integrated this new understanding into their daily life, how this work affected their private life as patients, and what we can learn from these changes for concepts of empowerment.Design, setting, and participants: A qualitative interview study. All SPs of Göttingen medical school who had been working longer than three semesters (n=14 were invited and agreed to take part in an open interview about their daily experience with real doctors. Documentary method was used to identify the main issues. Several cases were chosen according to maximum contrast and analysed by in-depth analysis to provide vivid examples of how simulations may affect the real life of the SPs as patients.Results: Our analysis revealed three main changes in the behaviour of SPs as real patients. They were more attentive, had a better understanding of the circumstances under which doctors work, and acted more self-confidently. From the selected cases it became apparent that working as a SP may lead to a constant and significant decrease of fear of hospitals and medical procedures or, in other cases, may enable the SPs to develop new abilities for giving feedback, questioning procedures, and explanations for real doctors.Conclusion: working as a simulated patient seems to be well-suited to understand own progression of diseases, to increase self-responsibility and to a confident attitude as patient.

  15. Creating Machinima (3D) and Real Life Videos in an ESP Classroom

    Science.gov (United States)

    Ochoa Alpala, Carol Anne; Ortíz García, William Ricardo

    2018-01-01

    This research paper reports on the development of oral presentation skills in a 3D virtual world called "Moviestorm" machinima, in contrast with real-life videos. In this way, the implementation of both types of videos sought to promote the improvement of oral communication skills, specifically oral presentations in a foreign language,…

  16. A novel dataset for real-life evaluation of facial expression recognition methodologies

    NARCIS (Netherlands)

    Siddiqi, Muhammad Hameed; Ali, Maqbool; Idris, Muhammad; Banos Legran, Oresti; Lee, Sungyoung; Choo, Hyunseung

    2016-01-01

    One limitation seen among most of the previous methods is that they were evaluated under settings that are far from real-life scenarios. The reason is that the existing facial expression recognition (FER) datasets are mostly pose-based and assume a predefined setup. The expressions in these datasets

  17. Center for Real Life Kitchen Design open house to showcase latest in residential kitchens

    OpenAIRE

    Elliott, Jean

    2007-01-01

    Virginia Tech will unveil its newly refurbished Center for Real Life Kitchen Design at an open house set for Monday, April 2. The 1,500-square foot center, located in 247 Wallace Hall, features six fully functional residential kitchen designs that reflect a variety of price levels, lifestyles, and use of space for today's homeowner.

  18. Reperfusion Treatment for STEMI in Age Over 75 Years: Unsatisfactory Real-Life Practice

    Czech Academy of Sciences Publication Activity Database

    Monhart, Z.; Grünfeldová, H.; Zvárová, Jana; Janský, P.

    2010-01-01

    Roč. 122, č. 2 (2010), e69 ISSN 0009-7322. [World Congress of Cardiology . 16.06.2010-19.06.2010, Beijing] Institutional research plan: CEZ:AV0Z10300504 Keywords : cardiology * reperfusion treatment * real-life practice Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery

  19. The Oral Language Process in Writing: A Real-Life Writing Session.

    Science.gov (United States)

    Shuy, Roger W.; Robinson, David G.

    1990-01-01

    Analyzes a real-life writing session involving a male executive in the construction business, his female secretary, and a male representing himself as a state official, working collaboratively to write a letter to a state official urging action on a long overdue claim. Discusses the quality of the drafts and the participants' roles. (KEH)

  20. Genetic influence on blood pressure measured in the office, under laboratory stress and during real life

    NARCIS (Netherlands)

    Wang, Xiaoling; Ding, Xiuhua; Su, Shaoyong; Harshfield, Gregory; Treiber, Frank; Snieder, Harold

    To determine to what extent the genetic influences on blood pressure (BP) measured in the office, under psychologically stressful conditions in the laboratory and during real life are different from each other. Office BP, BP during a video game challenge and a social stressor interview, and 24-h

  1. Group Creativity Development by Solving Real-life Project in Engineering Education

    DEFF Research Database (Denmark)

    Zhou, Chunfang; Kolmos, Anette; Du, Xiangyun

    2011-01-01

    In recent years, problem and project based learning (PBL) has been employed by a growing number of educational institutions to foster creative engineers. Among the diverse pedagogical practices of PBL, there has been an emergence of real-life project for students. Based on literature of creativity...... along with the learning activities etc., which are necessary for group creativity development in engineering students....

  2. Violence exposure in real-life, video games, television, movies, and the internet: is there desensitization?

    Science.gov (United States)

    Funk, Jeanne B; Baldacci, Heidi Bechtoldt; Pasold, Tracie; Baumgardner, Jennifer

    2004-02-01

    It is believed that repeated exposure to real-life and to entertainment violence may alter cognitive, affective, and behavioral processes, possibly leading to desensitization. The goal of the present study was to determine if there are relationships between real-life and media violence exposure and desensitization as reflected in related characteristics. One hundred fifty fourth and fifth graders completed measures of real-life violence exposure, media violence exposure, empathy, and attitudes towards violence. Regression analyses indicated that only exposure to video game violence was associated with (lower) empathy. Both video game and movie violence exposure were associated with stronger proviolence attitudes. The active nature of playing video games, intense engagement, and the tendency to be translated into fantasy play may explain negative impact, though causality was not investigated in the present design. The samples' relatively low exposure to real-life violence may have limited the identification of relationships. Although difficult to quantify, desensitization to violence should be further studied using related characteristics as in the present study. Individual differences and causal relationships should also be examined.

  3. The Forms and Functions of Real-Life Moral Decision-Making.

    Science.gov (United States)

    Krebs, Dennis L.; Denton, Kathy; Wark, Gillian

    1997-01-01

    Observes that the Kohlbergian model of morality does not give a good account of the ways in which people make moral decisions in their everyday lives. Argues that a functional model of moral judgment and moral behavior derived from evolutionary theory may supply a better account of real-life morality. (DSK)

  4. Engineers and the Web: An analysis of real life gaps in information usage

    NARCIS (Netherlands)

    Kraaijenbrink, Jeroen

    2007-01-01

    Engineers face a wide range of gaps when trying to identify, acquire, and utilize information from the Web. To be able to avoid creating such gaps, it is essential to understand them in detail. This paper reports the results of a study of the real life gaps in information usage processes of 17

  5. [The influences of interaction during online gaming on sociability and aggression in real life].

    Science.gov (United States)

    Fuji, Kei; Yoshida, Fujio

    2010-02-01

    This study examined the influences of online gaming on sociability and aggression in real life. It was hypothesized that the effects of online gaming would differ depending on the interaction style of the online-gamers. Online-gamers in Japan (n = 1 477) were asked to respond to questionnaires that measured interaction style during online gaming, the effects of sociability and aggression, as well as social and individual orientation in real life. Factor analysis of the scores for interaction style extracted five factors. Covariance structure analysis indicated that sociable interactions such as "Broadening relations" and "Feeling of belonging" promoted sociability in real life. In addition, "Release from daily hassles" promoted sociability and decreased aggression. In contrast, non-sociable and aggressive interactions decreased sociability and increased aggression. The results also suggested that a social orientation in real life promoted sociable interactions during game playing, while an individual orientation promoted non-sociable and aggressive interactions. These results supported the hypotheses and suggested that online gaming resulted in positive outcomes for those who are socially, but negative outcomes for those who are not.

  6. An adaptation framework for turning Real-Life Events into Games

    DEFF Research Database (Denmark)

    Kjærhus Therkildsen, Sacha; Cassøe Bunkenborg, Nanna; Larsen, Lasse Juel

    method and participatory design to achieve our ambition. In conclusion we found that a framework for persuasive board games can be advanced by balancing five interrelated layers: 1) real life events (game fiction), 2) rules (formal game elements), 3) movement system (game mechanisms), 4) destiny...

  7. Emotional Creativity and Real-Life Involvement in Different Types of Creative Leisure Activities

    Science.gov (United States)

    Trnka, Radek; Zahradnik, Martin; Kuška, Martin

    2016-01-01

    The role of emotional creativity in practicing creative leisure activities and in the preference of college majors remains unknown. This study aims to explore how emotional creativity measured by the Emotional Creativity Inventory (ECI; Averill, 1999) is interrelated with the real-life involvement in different types of specific creative leisure…

  8. Metacognition in Real Life Situations and Study Skills and Habits: Two Types of Processes

    Science.gov (United States)

    Al-Hilawani, Yasser A.

    2016-01-01

    The relationship between metacognition in real life situations and study skills and habits was examined using a sample of college students. Results showed no significant relationship between these two variables nor was there a significant relationship between study skills and reaction time as measured on the metacognitive test. However, there was…

  9. Children with Imaginary Companions Focus on Mental Characteristics When Describing Their Real-life Friends

    Science.gov (United States)

    Davis, Paige E.; Meins, Elizabeth; Fernyhough, Charles

    2014-01-01

    Relations between having an imaginary companion (IC) and (i) descriptions of a real-life friend, (ii) theory of mind performance, and (iii) reported prosocial behaviour and behavioural difficulties were investigated in a sample of 5-year-olds (N?=?159). Children who had an IC were more likely than their peers without an IC to describe their best…

  10. Quality of bystander cardiopulmonary resuscitation during real-life out-of-hospital cardiac arrest

    DEFF Research Database (Denmark)

    Gyllenborg, Tore; Granfeldt, Asger; Lippert, Freddy

    2017-01-01

    BACKGROUND: Cardiopulmonary resuscitation (CPR) can increase survival in out-of-hospital cardiac arrest (OHCA). However, little is known about bystander CPR quality in real-life OHCA. AIM: To describe bystander CPR quality based on automated external defibrillator (AED) CPR process data during OH...

  11. Development of a diagnostic decision tree for obstructive pulmonary diseases based on real-life data

    NARCIS (Netherlands)

    Metting, Esther I; In 't Veen, Johannes C C M; Dekhuijzen, P N Richard; van Heijst, Ellen; Kocks, Janwillem W H; Muilwijk-Kroes, Jacqueline B; Chavannes, Niels H; van der Molen, Thys

    2016-01-01

    The aim of this study was to develop and explore the diagnostic accuracy of a decision tree derived from a large real-life primary care population. Data from 9297 primary care patients (45% male, mean age 53±17 years) with suspicion of an obstructive pulmonary disease was derived from an

  12. How 4 Colleges Take on Veterans' Issues, in Research and Real Life

    Science.gov (United States)

    Sander, Libby

    2012-01-01

    This article features four colleges and how they take on veterans' issues in research and real life. These colleges are (1) Syracuse University; (2) Purdue University; (3) University of Southern California; and (4) University of North Carolina at Chapel Hill. Last year Syracuse established the Institute for Veterans and Military Families to focus…

  13. Moral Emotions and Moral Judgments in Children's Narratives: Comparing Real-Life and Hypothetical Transgressions

    Science.gov (United States)

    Gutzwiller-Helfenfinger, Eveline; Gasser, Luciano; Malti, Tina

    2010-01-01

    How children make meaning of their own social experiences in situations involving moral issues is central to their subsequent affective and cognitive moral learning. Our study of young children's narratives describing their interpersonal conflicts shows that the emotions and judgments constructed in the course of these real-life narratives differ…

  14. Real-life data for the optimization of the geometric layout of an intersection

    NARCIS (Netherlands)

    Fleuren, S.T.G.; Lefeber, A.A.J.

    2016-01-01

    This document contains the data of ten real-life intersections. This data can be used for the optimization of the geometric layout of the intersection, e.g., optimizing the arrival lanes, departure lanes and lane markings at the intersection.

  15. Ambiguity and risk measures in the lab and students’ real-life borrowing behavior

    NARCIS (Netherlands)

    Fairley, Kim; Weitzel, Utz

    This study analyzes the external validity of experimentally elicited ambiguity aversion, likelihood insensitivity and risk aversion on real-life decision-making in the field of student loans. Our main finding is that ambiguity aversion, likelihood insensitivity and risk aversion are not related to

  16. Real-Life Challenges in Using Augmentative and Alternative Communication by Persons with Amyotrophic Lateral Sclerosis

    Science.gov (United States)

    Ray, Jayanti

    2015-01-01

    Given the linguistic and cognitive demands of communication, adult Augmentative and Alternative Communication (AAC) users with acquired communication disorders may have difficulty using AAC systems consistently and effectively in "real-life" situations. The process of recommending AAC systems and strategies is an area of exploration,…

  17. The Use of a Real Life Simulated Problem Based Learning Activity in a Corporate Environment

    Science.gov (United States)

    Laurent, Mark A.

    2013-01-01

    This narrative study examines using a real life simulated problem base learning activity during education of clinical staff, which is expected to design and develop clinically correct electronic charting systems. Expertise in healthcare does not readily transcend to the realm of manipulating software to collect patient data that is pertinent to…

  18. AVEC 2017 - Real-life depression, and affect recognition workshop and challenge

    NARCIS (Netherlands)

    Ringeval, Fabien; Schuller, Bjorn; Valstar, Michel; Gratch, Jonathan; Cowie, Roddy; Scherer, Stefan; Mozgai, Sharon; Cummins, Nicholas; Schmitt, Maximilian; Pantic, Maja

    2017-01-01

    The Audio/Visual Emotion Challenge and Workshop (AVEC 2017) "Real-life depression, and affect" will be the seventh competition event aimed at comparison of multimedia processing and machine learning methods for automatic audiovisual depression and emotion analysis, with all participants competing

  19. Shelf Life of Food Products: From Open Labeling to Real-Time Measurements.

    Science.gov (United States)

    Corradini, Maria G

    2018-03-25

    The labels currently used on food and beverage products only provide consumers with a rough guide to their expected shelf lives because they assume that a product only experiences a limited range of predefined handling and storage conditions. These static labels do not take into consideration conditions that might shorten a product's shelf life (such as temperature abuse), which can lead to problems associated with food safety and waste. Advances in shelf-life estimation have the potential to improve the safety, reliability, and sustainability of the food supply. Selection of appropriate kinetic models and data-analysis techniques is essential to predict shelf life, to account for variability in environmental conditions, and to allow real-time monitoring. Novel analytical tools to determine safety and quality attributes in situ coupled with modern tracking technologies and appropriate predictive tools have the potential to provide accurate estimations of the remaining shelf life of a food product in real time. This review summarizes the necessary steps to attain a transition from open labeling to real-time shelf-life measurements.

  20. The Application of Real Convolution for Analytically Evaluating Fermi-Dirac-Type and Bose-Einstein-Type Integrals

    Directory of Open Access Journals (Sweden)

    Jerry P. Selvaggi

    2018-01-01

    Full Text Available The Fermi-Dirac-type or Bose-Einstein-type integrals can be transformed into two convergent real-convolution integrals. The transformation simplifies the integration process and may ultimately produce a complete analytical solution without recourse to any mathematical approximations. The real-convolution integrals can either be directly integrated or be transformed into the Laplace Transform inversion integral in which case the full power of contour integration becomes available. Which method is employed is dependent upon the complexity of the real-convolution integral. A number of examples are introduced which will illustrate the efficacy of the analytical approach.

  1. Analytic integration of real-virtual counterterms in NNLO jet cross sections II

    Energy Technology Data Exchange (ETDEWEB)

    Bolzoni, Paolo; Moch, Sven-Olaf [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Somogyi, Gabor [Zurich Univ. (Switzerland). Inst. fuer Theoretische Physik; Trocsanyi, Zoltan [Debrecen Univ. (Hungary); Hungarian Academy of Sciences, Debrecen (Hungary). Inst. of Nuclear Research

    2009-05-15

    We present analytic expressions of all integrals required to complete the explicit evaluation of the real-virtual integrated counterterms needed to define a recently proposed subtraction scheme for jet cross sections at next-to-next-to-leading order in QCD. We use the Mellin-Barnes representation of these integrals in 4-2{epsilon} dimensions to obtain the coefficients of their Laurent expansions around {epsilon}=0. These coefficients are given by linear combinations of multidimensional Mellin-Barnes integrals. We compute the coefficients of such expansions in {epsilon} both numerically and analytically by complex integration over the Mellin-Barnes contours. (orig.)

  2. Analytic integration of real-virtual counterterms in NNLO jet cross sections II

    International Nuclear Information System (INIS)

    Bolzoni, Paolo; Moch, Sven-Olaf; Somogyi, Gabor; Trocsanyi, Zoltan

    2009-01-01

    We present analytic expressions of all integrals required to complete the explicit evaluation of the real-virtual integrated counterterms needed to define a recently proposed subtraction scheme for jet cross sections at next-to-next-to-leading order in QCD. We use the Mellin-Barnes representation of these integrals in 4 - 2ε dimensions to obtain the coefficients of their Laurent expansions around ε = 0. These coefficients are given by linear combinations of multidimensional Mellin-Barnes integrals. We compute the coefficients of such expansions in ε both numerically and analytically by complex integration over the Mellin-Barnes contours.

  3. Analytic integration of real-virtual counterterms in NNLO jet cross sections II

    Science.gov (United States)

    Bolzoni, Paolo; Moch, Sven-Olaf; Somogyi, Gábor; Trócsányi, Zoltán

    2009-08-01

    We present analytic expressions of all integrals required to complete the explicit evaluation of the real-virtual integrated counterterms needed to define a recently proposed subtraction scheme for jet cross sections at next-to-next-to-leading order in QCD. We use the Mellin-Barnes representation of these integrals in 4 - 2epsilon dimensions to obtain the coefficients of their Laurent expansions around epsilon = 0. These coefficients are given by linear combinations of multidimensional Mellin-Barnes integrals. We compute the coefficients of such expansions in epsilon both numerically and analytically by complex integration over the Mellin-Barnes contours.

  4. Analytic integration of real-virtual counterterms in NNLO jet cross sections II

    International Nuclear Information System (INIS)

    Bolzoni, Paolo; Moch, Sven-Olaf; Somogyi, Gabor; Trocsanyi, Zoltan; Hungarian Academy of Sciences, Debrecen

    2009-05-01

    We present analytic expressions of all integrals required to complete the explicit evaluation of the real-virtual integrated counterterms needed to define a recently proposed subtraction scheme for jet cross sections at next-to-next-to-leading order in QCD. We use the Mellin-Barnes representation of these integrals in 4-2ε dimensions to obtain the coefficients of their Laurent expansions around ε=0. These coefficients are given by linear combinations of multidimensional Mellin-Barnes integrals. We compute the coefficients of such expansions in ε both numerically and analytically by complex integration over the Mellin-Barnes contours. (orig.)

  5. Project Orion, Environmental Control and Life Support System Integrated Studies

    Science.gov (United States)

    Russell, James F.; Lewis, John F.

    2008-01-01

    Orion is the next vehicle for human space travel. Humans will be sustained in space by the Orion subystem, environmental control and life support (ECLS). The ECLS concept at the subsystem level is outlined by function and technology. In the past two years, the interface definition with other subsystems has increased through different integrated studies. The paper presents the key requirements and discusses three recent studies (e.g., unpressurized cargo) along with the respective impacts on the ECLS design moving forward.

  6. Life stressors and social resources: an integrated assessment approach.

    Science.gov (United States)

    Moos, R H; Fenn, C B; Billings, A G

    1988-01-01

    The Life Stressors and Social Resources Inventory (LISRES) is described. The inventory provides an integrated assessment of an individual's life context. It taps both relatively stable and new aspects of life stressors and social resources in eight domains: physical health, home/neighborhood, financial, work, spouse/partner, children, extended family, and friends. The indices were developed on data obtained at two points in time from groups of depressed patients, alcoholic patients, arthritic patients, and healthy adults. The indices are internally consistent, moderately intercorrelated, and relatively stable over time. In addition, they are predictably related to changes in respondents' functioning. Although more developmental work is needed, the LISRES has some potential clinical and research applications and may be helpful in examining the process of stress and coping.

  7. Real-geographic-scenario-based virtual social environments: integrating geography with social research

    OpenAIRE

    Min Chen; Li He; Hui Lin; Chunxiao Zhang; Mingyuan Hu

    2013-01-01

    Existing online virtual worlds, or electronic environments, are of great significance to social science research, but are somewhat lacking in rigour. One reason is that users might not participate in those virtual worlds in the way they act in real daily life, communicating with each other in familiar environments and interacting with natural phenomena under the constraints of the human–land relationship. To help solve this problem we propose the real-geographic-scenario-based virtual social ...

  8. Reconstruction of biological networks based on life science data integration

    Directory of Open Access Journals (Sweden)

    Kormeier Benjamin

    2010-06-01

    Full Text Available For the implementation of the virtual cell, the fundamental question is how to model and simulate complex biological networks. Therefore, based on relevant molecular database and information systems, biological data integration is an essential step in constructing biological networks. In this paper, we will motivate the applications BioDWH - an integration toolkit for building life science data warehouses, CardioVINEdb - a information system for biological data in cardiovascular-disease and VANESA- a network editor for modeling and simulation of biological networks. Based on this integration process, the system supports the generation of biological network models. A case study of a cardiovascular-disease related gene-regulated biological network is also presented.

  9. Reconstruction of biological networks based on life science data integration.

    Science.gov (United States)

    Kormeier, Benjamin; Hippe, Klaus; Arrigo, Patrizio; Töpel, Thoralf; Janowski, Sebastian; Hofestädt, Ralf

    2010-10-27

    For the implementation of the virtual cell, the fundamental question is how to model and simulate complex biological networks. Therefore, based on relevant molecular database and information systems, biological data integration is an essential step in constructing biological networks. In this paper, we will motivate the applications BioDWH--an integration toolkit for building life science data warehouses, CardioVINEdb--a information system for biological data in cardiovascular-disease and VANESA--a network editor for modeling and simulation of biological networks. Based on this integration process, the system supports the generation of biological network models. A case study of a cardiovascular-disease related gene-regulated biological network is also presented.

  10. How Accumulated Real Life Stress Experience and Cognitive Speed Interact on Decision-Making Processes

    Directory of Open Access Journals (Sweden)

    Eva Friedel

    2017-06-01

    Full Text Available Rationale: Advances in neurocomputational modeling suggest that valuation systems for goal-directed (deliberative on one side, and habitual (automatic decision-making on the other side may rely on distinct computational strategies for reinforcement learning, namely model-free vs. model-based learning. As a key theoretical difference, the model-based system strongly demands cognitive functions to plan actions prospectively based on an internal cognitive model of the environment, whereas valuation in the model-free system relies on rather simple learning rules from operant conditioning to retrospectively associate actions with their outcomes and is thus cognitively less demanding. Acute stress reactivity is known to impair model-based but not model-free choice behavior, with higher working memory capacity protecting the model-based system from acute stress. However, it is not clear which impact accumulated real life stress has on model-free and model-based decision systems and how this influence interacts with cognitive abilities.Methods: We used a sequential decision-making task distinguishing relative contributions of both learning strategies to choice behavior, the Social Readjustment Rating Scale questionnaire to assess accumulated real life stress, and the Digit Symbol Substitution Test to test cognitive speed in 95 healthy subjects.Results: Individuals reporting high stress exposure who had low cognitive speed showed reduced model-based but increased model-free behavioral control. In contrast, subjects exposed to accumulated real life stress with high cognitive speed displayed increased model-based performance but reduced model-free control.Conclusion: These findings suggest that accumulated real life stress exposure can enhance reliance on cognitive speed for model-based computations, which may ultimately protect the model-based system from the detrimental influences of accumulated real life stress. The combination of accumulated real life

  11. In Patients With Cirrhosis, Driving Simulator Performance Is Associated With Real-life Driving.

    Science.gov (United States)

    Lauridsen, Mette M; Thacker, Leroy R; White, Melanie B; Unser, Ariel; Sterling, Richard K; Stravitz, Richard T; Matherly, Scott; Puri, Puneet; Sanyal, Arun J; Gavis, Edith A; Luketic, Velimir; Siddiqui, Muhammad S; Heuman, Douglas M; Fuchs, Michael; Bajaj, Jasmohan S

    2016-05-01

    Minimal hepatic encephalopathy (MHE) has been linked to higher real-life rates of automobile crashes and poor performance in driving simulation studies, but the link between driving simulator performance and real-life automobile crashes has not been clearly established. Furthermore, not all patients with MHE are unsafe drivers, but it is unclear how to distinguish them from unsafe drivers. We investigated the link between performance on driving simulators and real-life automobile accidents and traffic violations. We also aimed to identify features of unsafe drivers with cirrhosis and evaluated changes in simulated driving skills and MHE status after 1 year. We performed a study of outpatients with cirrhosis (n = 205; median 55 years old; median model for end-stage liver disease score, 9.5; none with overt hepatic encephalopathy or alcohol or illicit drug use within previous 6 months) seen at the Virginia Commonwealth University and McGuire Veterans Administration Medical Center, from November 2008 through April 2014. All participants were given paper-pencil tests to diagnose MHE (98 had MHE; 48%), and 163 patients completed a standardized driving simulation. Data were collected on traffic violations and automobile accidents from the Virginia Department of Motor Vehicles and from participants' self-assessments when they entered the study, and from 73 participants 1 year later. Participants also completed a questionnaire about alcohol use and cessation patterns. The driving simulator measured crashes, run-time, road center and edge excursions, and illegal turns during navigation; before and after each driving simulation session, patients were asked to rate their overall driving skills. Drivers were classified as safe or unsafe based on crashes and violations reported on official driving records; simulation results were compared with real-life driving records. Multivariable regression analyses of real-life crashes and violations was performed using data on

  12. Can virtual reality exposure therapy gains be generalized to real life? A meta-analysis of studies applying behavioral assessments

    NARCIS (Netherlands)

    Morina, N.; Ijntema, H.; Meyerbröker, K.; Emmelkamp, P.M.G.

    2015-01-01

    In virtual reality exposure therapy (VRET), patients are exposed to virtual environments that resemble feared real-life situations. The aim of the current study was to assess the extent to which VRET gains can be observed in real-life situations. We conducted a meta-analysis of clinical trials

  13. Integrated Oil spill detection and forecasting using MOON real time data

    OpenAIRE

    De Dominicis, M.; Pinardi, N.; Coppini, G.; Tonani, M.; Guarnieri, A.; Zodiatis, G.; Lardner, R.; Santoleri, R.

    2009-01-01

    MOON (Mediterranean Operational Oceanography Network) is an operational distributed system ready to provide quality controlled and timely marine observations (in situ and satellite) and environmental analyses and predictions for management of oil spill accidents. MOON operational systems are based upon the real time functioning of an integrated system composed of the Real Time Observing system, the regional, sub-regional and coastal forecasting systems and a products dissemination system. All...

  14. Chronic urticaria in the real-life clinical practice setting in Sweden, Norway and Denmark

    DEFF Research Database (Denmark)

    Thomsen, S F; Pritzier, E C; Anderson, C D

    2017-01-01

    ]; chronic urticaria quality of life questionnaire [CU-Q2 oL; Danish patients only]) and work productivity and activity impairment (WPAI) scores were also assessed. RESULTS: Overall, 158 CU patients from seven centres in Denmark (n = 80), Norway (n = 50) and Sweden (n = 28) were included in this baseline......BACKGROUND: Chronic urticaria (CU) is characterized by the recurrence of itchy hives and/or angioedema for more than 6 weeks. AWARE (A World-wide Antihistamine-Refractory Chronic Urticaria Patient Evaluation) is a multinational study designed to document the real-life treatment situation, burden...... (>2 months) that is refractory to H1-antihistamines. Baseline patient characteristics, disease activity (urticaria control test [UCT]), pharmacological treatment, comorbidities and healthcare usage were documented by the treating physician. Quality of life (QoL; dermatology life quality index [DLQI...

  15. Integration of Simulink, MARTe and MDSplus for rapid development of real-time applications

    Energy Technology Data Exchange (ETDEWEB)

    Manduchi, G., E-mail: gabriele.manduchi@igi.cnr.it [Consorzio RFX (CNR, ENEA, INFN, Università di Padova, Acciaierie Venete SpA), Padova (Italy); Luchetta, A.; Taliercio, C. [Consorzio RFX (CNR, ENEA, INFN, Università di Padova, Acciaierie Venete SpA), Padova (Italy); Neto, A.; Sartori, F. [Fusion for Energy, Barcelona (Spain); De Tommasi, G. [Fusion for Energy, Barcelona (Spain); Consorzio CREATE/DIETI, Università degli Studi di Napoli Federico II, Via Claudio 21, 80125 Napoli (Italy)

    2015-10-15

    Highlights: • The integration of two frameworks for real-time control and data acquisition is described. • The integration may significantly fasten the development of system components. • The system includes also a code generator for the integration of code written in Simulink. • A real-time control systemcan be implemented without the need of writing any line of code. - Abstract: Simulink is a graphical data flow programming tool for modeling and simulating dynamic systems. A component of Simulink, called Simulink Coder, generates C code from Simulink diagrams. MARTe is a framework for the implementation of real-time systems, currently in use in several fusion experiments. MDSplus is a framework widely used in the fusion community for the management of data. The three systems provide a solution to different facets of the same process, that is, real-time plasma control development. Simulink diagrams will describe the algorithms used in control, which will be implemented as MARTe GAMs and which will use parameters read from and produce results written to MDSplus pulse files. The three systems have been integrated in order to provide a tool suitable to speed up the development of real-time control applications. In particular, it will be shown how from a Simulink diagram describing a given algorithm to be used in a control system, it is possible to generate in an automated way the corresponding MARTe and MDSplus components that can be assembled to implement the target system.

  16. Integration of Simulink, MARTe and MDSplus for rapid development of real-time applications

    International Nuclear Information System (INIS)

    Manduchi, G.; Luchetta, A.; Taliercio, C.; Neto, A.; Sartori, F.; De Tommasi, G.

    2015-01-01

    Highlights: • The integration of two frameworks for real-time control and data acquisition is described. • The integration may significantly fasten the development of system components. • The system includes also a code generator for the integration of code written in Simulink. • A real-time control systemcan be implemented without the need of writing any line of code. - Abstract: Simulink is a graphical data flow programming tool for modeling and simulating dynamic systems. A component of Simulink, called Simulink Coder, generates C code from Simulink diagrams. MARTe is a framework for the implementation of real-time systems, currently in use in several fusion experiments. MDSplus is a framework widely used in the fusion community for the management of data. The three systems provide a solution to different facets of the same process, that is, real-time plasma control development. Simulink diagrams will describe the algorithms used in control, which will be implemented as MARTe GAMs and which will use parameters read from and produce results written to MDSplus pulse files. The three systems have been integrated in order to provide a tool suitable to speed up the development of real-time control applications. In particular, it will be shown how from a Simulink diagram describing a given algorithm to be used in a control system, it is possible to generate in an automated way the corresponding MARTe and MDSplus components that can be assembled to implement the target system.

  17. Integrated plant life management (PLiM)-the IAEA contribution

    International Nuclear Information System (INIS)

    Kang, K.-S.; Clark, C.R.; Omoto, A.; )

    2005-01-01

    For the past couple of decades there has been a change of emphasis in the world nuclear power from that of building new Nuclear Power Plants (NPP) to that of taking measures to optimize the life cycle of operational plants. National approaches in many countries showed an increase of interest in Plant Life Management (PLiM), both in terms of plant service life assurance and in optimizing the service or operational life of NPP. A strong convergence of views is emerging from different National approaches, particularly in the area of the economic aspects of NPP operation and in the evolution in the scope of NPP PLIM. The latter can directly affect the cost of electricity from NPP in an increasingly competitive environment. The safety considerations of a NPP are paramount and those requirements have to be met to obtain and to extend/renew the operating license. To achieve the goal of the long term safe, economic and reliable operation of the plant an integrated Plant Life Management Programme (PLiM) is necessary. Some countries already have advanced PLiM Programmes while others still have none. The PLiM objective is to identify all that factors and requirements for the overall plant life cycle. The optimization of these requirements would allow for the minimum period of the investment return and maximum of the revenue from the sell of the produced electricity. Recognizing the importance of this issue and in response to the requests of the Member States the IAEA Division of Nuclear Power implements the Sub-programme on 'Engineering and Management Support for Competitive Nuclear Power'. Four projects within this sub-programme deal with different aspects of the NPP life cycle management with the aim to increase the capabilities of interested Member States in implementing and maintenance of the competitive and sustainable nuclear power. Although all four projects contain certain issues of PLiM there is one specific project on guidance on engineering and management practices

  18. Advancing Integrated Systems Modelling Framework for Life Cycle Sustainability Assessment

    Directory of Open Access Journals (Sweden)

    Anthony Halog

    2011-02-01

    Full Text Available The need for integrated methodological framework for sustainability assessment has been widely discussed and is urgent due to increasingly complex environmental system problems. These problems have impacts on ecosystems and human well-being which represent a threat to economic performance of countries and corporations. Integrated assessment crosses issues; spans spatial and temporal scales; looks forward and backward; and incorporates multi-stakeholder inputs. This study aims to develop an integrated methodology by capitalizing the complementary strengths of different methods used by industrial ecologists and biophysical economists. The computational methodology proposed here is systems perspective, integrative, and holistic approach for sustainability assessment which attempts to link basic science and technology to policy formulation. The framework adopts life cycle thinking methods—LCA, LCC, and SLCA; stakeholders analysis supported by multi-criteria decision analysis (MCDA; and dynamic system modelling. Following Pareto principle, the critical sustainability criteria, indicators and metrics (i.e., hotspots can be identified and further modelled using system dynamics or agent based modelling and improved by data envelopment analysis (DEA and sustainability network theory (SNT. The framework is being applied to development of biofuel supply chain networks. The framework can provide new ways of integrating knowledge across the divides between social and natural sciences as well as between critical and problem-solving research.

  19. Analytic integration of real-virtual counterterms in NNLO jet cross sections I

    Science.gov (United States)

    Aglietti, Ugo; Del Duca, Vittorio; Duhr, Claude; Somogyi, Gábor; Trócsányi, Zoltán

    2008-09-01

    We present analytic evaluations of some integrals needed to give explicitly the integrated real-virtual counterterms, based on a recently proposed subtraction scheme for next-to-next-to-leading order (NNLO) jet cross sections. After an algebraic reduction of the integrals, integration-by-parts identities are used for the reduction to master integrals and for the computation of the master integrals themselves by means of differential equations. The results are written in terms of one- and two-dimensional harmonic polylogarithms, once an extension of the standard basis is made. We expect that the techniques described here will be useful in computing other integrals emerging in calculations in perturbative quantum field theories.

  20. Social Anxiety in Online and Real-Life Interaction and Their Associated Factors

    Science.gov (United States)

    Yen, Ju-Yu; Yen, Cheng-Fang; Chen, Cheng-Sheng; Wang, Peng-Wei; Chang, Yi-Hsin

    2012-01-01

    Abstract Social anxiety was compared between online and real-life interaction in a sample of 2,348 college students. Severity of social anxiety in both real-life and online interaction was tested for associations with depression, Internet addiction, Internet activity type (gaming versus chatting), and scores on Behavioral Inhibition System (BIS)/Behavioral Activation System (BAS) scales. The results showed that social anxiety was lower when interacting online than when interacting offline. Depression, Internet addiction, and high BIS and BAS scores were associated with high social anxiety. The social anxiety decreased more in online interaction among subjects with high social anxiety, depression, BIS, and BAS. This result suggests that the Internet has good potential as an alternative medium for delivering interventions for social anxiety. Further, the effect of BIS on social anxiety is decreased in online interaction. More attention should be paid for BIS when the treatment for social anxiety is delivered online. PMID:22175853

  1. Social anxiety in online and real-life interaction and their associated factors.

    Science.gov (United States)

    Yen, Ju-Yu; Yen, Cheng-Fang; Chen, Cheng-Sheng; Wang, Peng-Wei; Chang, Yi-Hsin; Ko, Chih-Hung

    2012-01-01

    Social anxiety was compared between online and real-life interaction in a sample of 2,348 college students. Severity of social anxiety in both real-life and online interaction was tested for associations with depression, Internet addiction, Internet activity type (gaming versus chatting), and scores on Behavioral Inhibition System (BIS)/Behavioral Activation System (BAS) scales. The results showed that social anxiety was lower when interacting online than when interacting offline. Depression, Internet addiction, and high BIS and BAS scores were associated with high social anxiety. The social anxiety decreased more in online interaction among subjects with high social anxiety, depression, BIS, and BAS. This result suggests that the Internet has good potential as an alternative medium for delivering interventions for social anxiety. Further, the effect of BIS on social anxiety is decreased in online interaction. More attention should be paid for BIS when the treatment for social anxiety is delivered online.

  2. A Simple Method for Solving Fully Intuitionistic Fuzzy Real Life Assignment Problem

    OpenAIRE

    Senthil Kumar, P.; Jahir Hussain, R.

    2016-01-01

    In solving real life assignment problem we often face the state of uncertainty as well as hesitation due to various uncontrollable factors. To deal with uncertainty and hesitation many authors have suggested the intuitionistic fuzzy representations for the data. So, in this paper, the authors consider the assignment problem having uncertainty and hesitation in cost/time/profit. They formulate the problem and utilize triangular intuitionistic fuzzy numbers (TIFNs) to deal with uncertainty and ...

  3. Virginia Tech's Center For Real Life Kitchen Design Is A Success!

    OpenAIRE

    Todd, Jane Anne

    2003-01-01

    Explore Your Dream Kitchen, a two-day workshop offered in Virginia Tech's Center for Real Life Kitchen Design, will be offered twice in May to participants who want to learn about planning and designing a kitchen that really meets their needs. Attendees explore and experience kitchens with a wide variety of designs, products, materials, and technologies during this fun and interactive course. Participants are asked to bring plans, ideas, and questions about their homes and kitchens as everyon...

  4. Framing Mass Shootings: Fictional Depictions of Real-life Gun Massacres in American Cinema

    OpenAIRE

    Tryggeseid, Ane Johannessen

    2017-01-01

    This thesis examines the concept of real-life mass shootings and its depiction in American fictional cinema. The issue of mass shootings is a highly controversial subject of discussion, both within the public and political sphere, as it necessarily touches upon rigid perceptions of civil liberties – specifically those of the Second Amendment – which further permeates the field of fictional cinema. As opposed to assessing the issue of mass shootings as a product of a prevailing culture of guns...

  5. Development of a diagnostic decision tree for obstructive pulmonary diseases based on real-life data

    Directory of Open Access Journals (Sweden)

    Esther I. Metting

    2016-01-01

    Full Text Available The aim of this study was to develop and explore the diagnostic accuracy of a decision tree derived from a large real-life primary care population. Data from 9297 primary care patients (45% male, mean age 53±17 years with suspicion of an obstructive pulmonary disease was derived from an asthma/chronic obstructive pulmonary disease (COPD service where patients were assessed using spirometry, the Asthma Control Questionnaire, the Clinical COPD Questionnaire, history data and medication use. All patients were diagnosed through the Internet by a pulmonologist. The Chi-squared Automatic Interaction Detection method was used to build the decision tree. The tree was externally validated in another real-life primary care population (n=3215. Our tree correctly diagnosed 79% of the asthma patients, 85% of the COPD patients and 32% of the asthma–COPD overlap syndrome (ACOS patients. External validation showed a comparable pattern (correct: asthma 78%, COPD 83%, ACOS 24%. Our decision tree is considered to be promising because it was based on real-life primary care patients with a specialist's diagnosis. In most patients the diagnosis could be correctly predicted. Predicting ACOS, however, remained a challenge. The total decision tree can be implemented in computer-assisted diagnostic systems for individual patients. A simplified version of this tree can be used in daily clinical practice as a desk tool.

  6. Development of a diagnostic decision tree for obstructive pulmonary diseases based on real-life data

    Science.gov (United States)

    in ’t Veen, Johannes C.C.M.; Dekhuijzen, P.N. Richard; van Heijst, Ellen; Kocks, Janwillem W.H.; Muilwijk-Kroes, Jacqueline B.; Chavannes, Niels H.; van der Molen, Thys

    2016-01-01

    The aim of this study was to develop and explore the diagnostic accuracy of a decision tree derived from a large real-life primary care population. Data from 9297 primary care patients (45% male, mean age 53±17 years) with suspicion of an obstructive pulmonary disease was derived from an asthma/chronic obstructive pulmonary disease (COPD) service where patients were assessed using spirometry, the Asthma Control Questionnaire, the Clinical COPD Questionnaire, history data and medication use. All patients were diagnosed through the Internet by a pulmonologist. The Chi-squared Automatic Interaction Detection method was used to build the decision tree. The tree was externally validated in another real-life primary care population (n=3215). Our tree correctly diagnosed 79% of the asthma patients, 85% of the COPD patients and 32% of the asthma–COPD overlap syndrome (ACOS) patients. External validation showed a comparable pattern (correct: asthma 78%, COPD 83%, ACOS 24%). Our decision tree is considered to be promising because it was based on real-life primary care patients with a specialist's diagnosis. In most patients the diagnosis could be correctly predicted. Predicting ACOS, however, remained a challenge. The total decision tree can be implemented in computer-assisted diagnostic systems for individual patients. A simplified version of this tree can be used in daily clinical practice as a desk tool. PMID:27730177

  7. Idiopathic pulmonary fibrosis: from clinical trials to real-life experiences

    Directory of Open Access Journals (Sweden)

    Sergio Harari

    2015-09-01

    Full Text Available Randomised controlled clinical trials are fundamental in medicine to develop new effective drugs and new therapeutic regimens and are the strength of evidence-based medicine. These studies allow us to avoid the repetition of misleading experiences that have been reported in the past, where drugs or associations were utilised without compelling evidence and ultimately proven to be ineffective. In recent years, randomised clinical trials have been conducted and concluded for many rare diseases, including idiopathic pulmonary fibrosis. However, clinical trials do not always reflect the real-life scenario. Patients selected for clinical trials present fewer comorbidities, they fall between certain age limits, and the severity of their disease is defined; therefore, they do not always reflect the whole of the population affected by a specific disease. These are the reasons why we also need data that mirror real-life experience. The limitations that these kind of studies present are always several and the studies should be interpreted with caution, although they can fill the important gap between efficacy and effectiveness. In this article, we will review the existing clinical data on real-life treatment of idiopathic pulmonary fibrosis.

  8. Life-cycle analysis of product integrated polymer solar cells

    DEFF Research Database (Denmark)

    Espinosa Martinez, Nieves; García-Valverde, Rafael; Krebs, Frederik C

    2011-01-01

    A life cycle analysis (LCA) on a product integrated polymer solar module is carried out in this study. These assessments are well-known to be useful in developmental stages of a product in order to identify the bottlenecks for the up-scaling in its production phase for several aspects spanning from...... economics through design to functionality. An LCA study was performed to quantify the energy use and greenhouse gas (GHG) emissions from electricity use in the manufacture of a light-weight lamp based on a plastic foil, a lithium-polymer battery, a polymer solar cell, printed circuitry, blocking diode......, switch and a white light emitting semiconductor diode. The polymer solar cell employed in this prototype presents a power conversion efficiency in the range of 2 to 3% yielding energy payback times (EPBT) in the range of 1.3–2 years. Based on this it is worthwhile to undertake a life-cycle study...

  9. Process integrated modelling for steelmaking Life Cycle Inventory analysis

    International Nuclear Information System (INIS)

    Iosif, Ana-Maria; Hanrot, Francois; Ablitzer, Denis

    2008-01-01

    During recent years, strict environmental regulations have been implemented by governments for the steelmaking industry in order to reduce their environmental impact. In the frame of the ULCOS project, we have developed a new methodological framework which combines the process integrated modelling approach with Life Cycle Assessment (LCA) method in order to carry out the Life Cycle Inventory of steelmaking. In the current paper, this new concept has been applied to the sinter plant which is the most polluting steelmaking process. It has been shown that this approach is a powerful tool to make the collection of data easier, to save time and to provide reliable information concerning the environmental diagnostic of the steelmaking processes

  10. Integrated design strategy for product life-cycle management

    Science.gov (United States)

    Johnson, G. Patrick

    2001-02-01

    Two major trends suggest new considerations for environmentally conscious manufacturing (ECM) -- the continuation of dematerialization and the growing trend toward goods becoming services. A diversity of existing research could be integrated around those trends in ways that can enhance ECM. Major research-based achievements in information, computation, and communications systems, sophisticated and inexpensive sensing capabilities, highly automated and precise manufacturing technologies, and new materials continue to drive the phenomenon of dematerialization - the reduction of the material and energy content of per capita GDP. Knowledge is also growing about the sociology, economics, mathematics, management and organization of complex socio-economic systems. And that has driven a trend towards goods evolving into services. But even with these significant trends, the value of material, energy, information and human resources incorporated into the manufacture, use and disposal of modern products and services often far exceeds the benefits realized. Multi-disciplinary research integrating these drivers with advances in ECM concepts could be the basis for a new strategy of production. It is argued that a strategy of integrating information resources with physical and human resources over product life cycles, together with considering products as streams of service over time, could lead to significant economic payoff. That strategy leads to an overall design concept to minimize costs of all resources over the product life cycle to more fully capture benefits of all resources incorporated into modern products. It is possible by including life cycle monitoring, periodic component replacement, re-manufacture, salvage and human factor skill enhancement into initial design.

  11. West-Life, Tools for Integrative Structural Biology

    CERN Multimedia

    CERN. Geneva

    2018-01-01

    Structural biology is part of molecular biology focusing on determining structure of macromolecules inside living cells and cell membranes. As macromolecules determines most of the functions of cells the structural knowledge is very useful for further research in metabolism, physiology to application in pharmacology etc. As macromolecules are too small to be observed directly by light microscope, there are other methods used to determine the structure including nuclear magnetic resonance (NMR), X-Ray crystalography, cryo electron microscopy and others. Each method has it's advantages and disadvantages in the terms of availability, sample preparation, resolution. West-Life project has ambition to facilitate integrative approach using multiple techniques mentioned above. As there are already lot of software tools to process data produced by the techniques above, the challenge is to integrate them together in a way they can be used by experts in one technique but not experts in other techniques. One product ...

  12. INTEGRITY ANALYSIS OF REAL-TIME PPP TECHNIQUE WITH IGS-RTS SERVICE FOR MARITIME NAVIGATION

    Directory of Open Access Journals (Sweden)

    M. El-Diasty

    2017-10-01

    Full Text Available Open sea and inland waterways are the most widely used mode for transporting goods worldwide. It is the International Maritime Organization (IMO that defines the requirements for position fixing equipment for a worldwide radio-navigation system, in terms of accuracy, integrity, continuity, availability and coverage for the various phases of navigation. Satellite positioning systems can contribute to meet these requirements, as well as optimize marine transportation. Marine navigation usually consists of three major phases identified as Ocean/Coastal/Port approach/Inland waterway, in port navigation and automatic docking with alert limit ranges from 25 m to 0.25 m. GPS positioning is widely used for many applications and is currently recognized by IMO for a future maritime navigation. With the advancement in autonomous GPS positioning techniques such as Precise Point Positioning (PPP and with the advent of new real-time GNSS correction services such as IGS-Real-Time-Service (RTS, it is necessary to investigate the integrity of the PPP-based positioning technique along with IGS-RTS service in terms of availability and reliability for safe navigation in maritime application. This paper monitors the integrity of an autonomous real-time PPP-based GPS positioning system using the IGS real-time service (RTS for maritime applications that require minimum availability of integrity of 99.8 % to fulfil the IMO integrity standards. To examine the integrity of the real-time IGS-RTS PPP-based technique for maritime applications, kinematic data from a dual frequency GPS receiver is collected onboard a vessel and investigated with the real-time IGS-RTS PPP-based GPS positioning technique. It is shown that the availability of integrity of the real-time IGS-RTS PPP-based GPS solution is 100 % for all navigation phases and therefore fulfil the IMO integrity standards (99.8 % availability immediately (after 1 second, after 2 minutes and after 42 minutes

  13. Integrity Analysis of Real-Time Ppp Technique with Igs-Rts Service for Maritime Navigation

    Science.gov (United States)

    El-Diasty, M.

    2017-10-01

    Open sea and inland waterways are the most widely used mode for transporting goods worldwide. It is the International Maritime Organization (IMO) that defines the requirements for position fixing equipment for a worldwide radio-navigation system, in terms of accuracy, integrity, continuity, availability and coverage for the various phases of navigation. Satellite positioning systems can contribute to meet these requirements, as well as optimize marine transportation. Marine navigation usually consists of three major phases identified as Ocean/Coastal/Port approach/Inland waterway, in port navigation and automatic docking with alert limit ranges from 25 m to 0.25 m. GPS positioning is widely used for many applications and is currently recognized by IMO for a future maritime navigation. With the advancement in autonomous GPS positioning techniques such as Precise Point Positioning (PPP) and with the advent of new real-time GNSS correction services such as IGS-Real-Time-Service (RTS), it is necessary to investigate the integrity of the PPP-based positioning technique along with IGS-RTS service in terms of availability and reliability for safe navigation in maritime application. This paper monitors the integrity of an autonomous real-time PPP-based GPS positioning system using the IGS real-time service (RTS) for maritime applications that require minimum availability of integrity of 99.8 % to fulfil the IMO integrity standards. To examine the integrity of the real-time IGS-RTS PPP-based technique for maritime applications, kinematic data from a dual frequency GPS receiver is collected onboard a vessel and investigated with the real-time IGS-RTS PPP-based GPS positioning technique. It is shown that the availability of integrity of the real-time IGS-RTS PPP-based GPS solution is 100 % for all navigation phases and therefore fulfil the IMO integrity standards (99.8 % availability) immediately (after 1 second), after 2 minutes and after 42 minutes of convergence

  14. Towards a portable microchip system with integrated thermal control and polymer waveguides for real-time PCR

    DEFF Research Database (Denmark)

    Wang, Zhenyu; Sekulovic, Andrea; Kutter, Jörg Peter

    2006-01-01

    A novel real-time PCR microchip platform with integrated thermal system and polymer waveguides has been developed. The integrated polymer optical system for real-time monitoring of PCR was fabricated in the same SU-8 layer as the PCR chamber, without additional masking steps. Two suitable DNA...... binding dyes, SYTOX Orange and TO-PRO-3, were selected and tested for the real-time PCR processes. As a model, cadF gene of Campylobacter jejuni has been amplified on the microchip. Using the integrated optical system of the real-time PCR microchip, the measured cycle threshold values of the real-time PCR...

  15. On-Board Real-Time Optimization Control for Turbo-Fan Engine Life Extending

    Science.gov (United States)

    Zheng, Qiangang; Zhang, Haibo; Miao, Lizhen; Sun, Fengyong

    2017-11-01

    A real-time optimization control method is proposed to extend turbo-fan engine service life. This real-time optimization control is based on an on-board engine mode, which is devised by a MRR-LSSVR (multi-input multi-output recursive reduced least squares support vector regression method). To solve the optimization problem, a FSQP (feasible sequential quadratic programming) algorithm is utilized. The thermal mechanical fatigue is taken into account during the optimization process. Furthermore, to describe the engine life decaying, a thermal mechanical fatigue model of engine acceleration process is established. The optimization objective function not only contains the sub-item which can get fast response of the engine, but also concludes the sub-item of the total mechanical strain range which has positive relationship to engine fatigue life. Finally, the simulations of the conventional optimization control which just consider engine acceleration performance or the proposed optimization method have been conducted. The simulations demonstrate that the time of the two control methods from idle to 99.5 % of the maximum power are equal. However, the engine life using the proposed optimization method could be surprisingly increased by 36.17 % compared with that using conventional optimization control.

  16. Fully integrated microfluidic measurement system for real-time determination of gas and liquid mixtures composition

    NARCIS (Netherlands)

    Lötters, Joost Conrad; Groenesteijn, Jarno; van der Wouden, E.J.; Sparreboom, Wouter; Lammerink, Theodorus S.J.; Wiegerink, Remco J.

    2015-01-01

    We have designed and realised a fully integrated microfluidic measurement system for real-time determination of both flow rate and composition of gas- and liquid mixtures. The system comprises relative permittivity sensors, pressure sensors, a Coriolis flow and density sensor, a thermal flow sensor

  17. Feasibility of real-time calculation of correlation integral derived statistics applied to EGG time series

    NARCIS (Netherlands)

    van den Broek, PLC; van Egmond, J; van Rijn, CM; Takens, F; Coenen, AML; Booij, LHDJ

    2005-01-01

    Background: This study assessed the feasibility of online calculation of the correlation integral (C(r)) aiming to apply C(r)derived statistics. For real-time application it is important to reduce calculation time. It is shown how our method works for EEG time series. Methods: To achieve online

  18. Feasibility of real-time calculation of correlation integral derived statistics applied to EEG time series

    NARCIS (Netherlands)

    Broek, P.L.C. van den; Egmond, J. van; Rijn, C.M. van; Takens, F.; Coenen, A.M.L.; Booij, L.H.D.J.

    2005-01-01

    This study assessed the feasibility of online calculation of the correlation integral (C(r)) aiming to apply C(r)-derived statistics. For real-time application it is important to reduce calculation time. It is shown how our method works for EEG time series. Methods: To achieve online calculation of

  19. Medical Device Integrated Vital Signs Monitoring Application with Real-Time Clinical Decision Support.

    Science.gov (United States)

    Moqeem, Aasia; Baig, Mirza; Gholamhosseini, Hamid; Mirza, Farhaan; Lindén, Maria

    2018-01-01

    This research involves the design and development of a novel Android smartphone application for real-time vital signs monitoring and decision support. The proposed application integrates market available, wireless and Bluetooth connected medical devices for collecting vital signs. The medical device data collected by the app includes heart rate, oxygen saturation and electrocardiograph (ECG). The collated data is streamed/displayed on the smartphone in real-time. This application was designed by adopting six screens approach (6S) mobile development framework and focused on user-centered approach and considered clinicians-as-a-user. The clinical engagement, consultations, feedback and usability of the application in the everyday practices were considered critical from the initial phase of the design and development. Furthermore, the proposed application is capable to deliver rich clinical decision support in real-time using the integrated medical device data.

  20. Note: Fully integrated 3.2 Gbps quantum random number generator with real-time extraction

    International Nuclear Information System (INIS)

    Zhang, Xiao-Guang; Nie, You-Qi; Liang, Hao; Zhang, Jun; Pan, Jian-Wei; Zhou, Hongyi; Ma, Xiongfeng

    2016-01-01

    We present a real-time and fully integrated quantum random number generator (QRNG) by measuring laser phase fluctuations. The QRNG scheme based on laser phase fluctuations is featured for its capability of generating ultra-high-speed random numbers. However, the speed bottleneck of a practical QRNG lies on the limited speed of randomness extraction. To close the gap between the fast randomness generation and the slow post-processing, we propose a pipeline extraction algorithm based on Toeplitz matrix hashing and implement it in a high-speed field-programmable gate array. Further, all the QRNG components are integrated into a module, including a compact and actively stabilized interferometer, high-speed data acquisition, and real-time data post-processing and transmission. The final generation rate of the QRNG module with real-time extraction can reach 3.2 Gbps.

  1. Note: Fully integrated 3.2 Gbps quantum random number generator with real-time extraction

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Xiao-Guang; Nie, You-Qi; Liang, Hao; Zhang, Jun, E-mail: zhangjun@ustc.edu.cn; Pan, Jian-Wei [Hefei National Laboratory for Physical Sciences at the Microscale and Department of Modern Physics, University of Science and Technology of China, Hefei, Anhui 230026 (China); CAS Center for Excellence and Synergetic Innovation Center in Quantum Information and Quantum Physics, University of Science and Technology of China, Hefei, Anhui 230026 (China); Zhou, Hongyi; Ma, Xiongfeng [Center for Quantum Information, Institute for Interdisciplinary Information Sciences, Tsinghua University, Beijing 100084 (China)

    2016-07-15

    We present a real-time and fully integrated quantum random number generator (QRNG) by measuring laser phase fluctuations. The QRNG scheme based on laser phase fluctuations is featured for its capability of generating ultra-high-speed random numbers. However, the speed bottleneck of a practical QRNG lies on the limited speed of randomness extraction. To close the gap between the fast randomness generation and the slow post-processing, we propose a pipeline extraction algorithm based on Toeplitz matrix hashing and implement it in a high-speed field-programmable gate array. Further, all the QRNG components are integrated into a module, including a compact and actively stabilized interferometer, high-speed data acquisition, and real-time data post-processing and transmission. The final generation rate of the QRNG module with real-time extraction can reach 3.2 Gbps.

  2. Real-time long term measurement using integrated framework for ubiquitous smart monitoring

    Science.gov (United States)

    Heo, Gwanghee; Lee, Giu; Lee, Woosang; Jeon, Joonryong; Kim, Pil-Joong

    2007-04-01

    Ubiquitous monitoring combining internet technologies and wireless communication is one of the most promising technologies of infrastructure health monitoring against the natural of man-made hazards. In this paper, an integrated framework of the ubiquitous monitoring is developed for real-time long term measurement in internet environment. This framework develops a wireless sensor system based on Bluetooth technology and sends measured acceleration data to the host computer through TCP/IP protocol. And it is also designed to respond to the request of web user on real time basis. In order to verify this system, real time monitoring tests are carried out on a prototype self-anchored suspension bridge. Also, wireless measurement system is analyzed to estimate its sensing capacity and evaluate its performance for monitoring purpose. Based on the evaluation, this paper proposes the effective strategies for integrated framework in order to detect structural deficiencies and to design an early warning system.

  3. Stability Analysis and Variational Integrator for Real-Time Formation Based on Potential Field

    Directory of Open Access Journals (Sweden)

    Shengqing Yang

    2014-01-01

    Full Text Available This paper investigates a framework of real-time formation of autonomous vehicles by using potential field and variational integrator. Real-time formation requires vehicles to have coordinated motion and efficient computation. Interactions described by potential field can meet the former requirement which results in a nonlinear system. Stability analysis of such nonlinear system is difficult. Our methodology of stability analysis is discussed in error dynamic system. Transformation of coordinates from inertial frame to body frame can help the stability analysis focus on the structure instead of particular coordinates. Then, the Jacobian of reduced system can be calculated. It can be proved that the formation is stable at the equilibrium point of error dynamic system with the effect of damping force. For consideration of calculation, variational integrator is introduced. It is equivalent to solving algebraic equations. Forced Euler-Lagrange equation in discrete expression is used to construct a forced variational integrator for vehicles in potential field and obstacle environment. By applying forced variational integrator on computation of vehicles' motion, real-time formation of vehicles in obstacle environment can be implemented. Algorithm based on forced variational integrator is designed for a leader-follower formation.

  4. Life-crossroads on stage: integrating life review and drama therapy for older adults.

    Science.gov (United States)

    Keisari, Shoshi; Palgi, Yuval

    2017-10-01

    This paper examines the contribution of a new group of therapeutic interventions for older adults, based on a rudimentary life-review intervention. The intervention includes narrative elements together with drama therapy. The current study examines the influence of this therapeutic intervention on key indicators of mental health and psychological well-being among older adults. Fifty-five people (n = 55), ranging in age from 62 to 93, participated in a before-after study design. The following indices - meaning in life, self-acceptance, relationships with others, depressive symptoms, and experience of successful aging - were compared between an intervention group (n = 27) and a care-as-usual control group (n = 28). Repeated measures analyses of variance showed a significant improvement over time in the experimental group. In addition, results also showed time-group interaction regarding the treatment's effectiveness for self-acceptance, relationships with others, sense of meaning in life, sense of successful aging, and depressive symptoms. Our findings confirm that the new therapeutic intervention, which integrates life-review with drama therapy, increases self-acceptance, relationships with others, sense of meaning in life, and sense of successful aging; in turn, it also decreases depressive symptoms among older adults. The contribution of this research is based on the development of a therapeutic intervention that combines narrative together with drama therapy tools, which can be used in focused and short-term group treatments with the elderly.

  5. French nuclear plants PWR vessel integrity assessment and life management

    Energy Technology Data Exchange (ETDEWEB)

    Bezdikian, G. [Electricite de France (EDF), Div. Production Nucleaire, 93 - Saint-Denis (France); Quinot, P. [FRAMATOME, Dept. Bloc Reacteur et Boucles Primaires, 92 - Paris-La-Defence (France); Faidy, C.; Churier-Bossennec, H. [Electricite de France (EDF), Div. Ingenierie et Service, 69 - Villeurbanne (France)

    2001-07-01

    The Reactor Pressure Vessel life management of 56 PWR 3 loop and 4 loop reactors units was engaged by the French Utility EDF (Electricite de France) a few years ago and is yet on going on. This paper will present the work carried out within the framework of justifying why the 34 three loop reactor vessels will remain acceptable for operation for a lifetime of at least 40-years. A summary of the measures will be given. An overall review of actions will be presented describing the French approach, using important existing databases, including studies related to irradiation surveillance monitoring program and end of life fluence assessment. The last results obtained are based on generic integrity analyses for all categories of situations (normal upset emergency and faulted conditions) until the end of lifetime, postulating circumferential an radial kinds of flaw located in the stainless steel cladding or shallow sub-cladding area. The results of structural integrity analyses beginning with elastic computations and completed with three-dimensional finite element elastic plastic computations for envelope cases, are compared with code criteria for operating plants. The objective is to evaluate the margins on different parameters as RTNDT (Reference Nil Ductility Transition Temperature), toughness or crack size, to justify the global fitness for service of all these Reactor Pressure Vessels. The paper introduces EDF's maintenance strategy, related to integrity assessment, for those nuclear power plants under operation, based on NDE in-service inspection of the first thirty millimeters in the thickness of the wall and major surveillance programs of the vessels. (author)

  6. French nuclear plants PWR vessel integrity assessment and life management

    International Nuclear Information System (INIS)

    Bezdikian, G.; Quinot, P.; Faidy, C.; Churier-Bossennec, H.

    2001-01-01

    The Reactor Pressure Vessel life management of 56 PWR 3 loop and 4 loop reactors units was engaged by the French Utility EDF (Electricite de France) a few years ago and is yet on going on. This paper will present the work carried out within the framework of justifying why the 34 three loop reactor vessels will remain acceptable for operation for a lifetime of at least 40-years. A summary of the measures will be given. An overall review of actions will be presented describing the French approach, using important existing databases, including studies related to irradiation surveillance monitoring program and end of life fluence assessment. The last results obtained are based on generic integrity analyses for all categories of situations (normal upset emergency and faulted conditions) until the end of lifetime, postulating circumferential an radial kinds of flaw located in the stainless steel cladding or shallow sub-cladding area. The results of structural integrity analyses beginning with elastic computations and completed with three-dimensional finite element elastic plastic computations for envelope cases, are compared with code criteria for operating plants. The objective is to evaluate the margins on different parameters as RTNDT (Reference Nil Ductility Transition Temperature), toughness or crack size, to justify the global fitness for service of all these Reactor Pressure Vessels. The paper introduces EDF's maintenance strategy, related to integrity assessment, for those nuclear power plants under operation, based on NDE in-service inspection of the first thirty millimeters in the thickness of the wall and major surveillance programs of the vessels. (author)

  7. Quality of Life Theory I. The IQOL Theory: An Integrative Theory of the Global Quality of Life Concept

    Directory of Open Access Journals (Sweden)

    Soren Ventegodt

    2003-01-01

    Full Text Available Quality of life (QOL means a good life and we believe that a good life is the same as living a life with a high quality. This paper presents the theoretical and philosophical framework of the Danish Quality of Life Survey, and of the SEQOL, QOL5, and QOL1 questionnaires.The notion of a good life can be observed from subjective to the objective, where this spectrum incorporates a number of existing quality of life theories. We call this spectrum the integrative quality-of-life (IQOL theory and discuss the following aspects in this paper: well being, satisfaction with life, happiness, meaning in life, the biological information system (�balance�, realizing life potential, fulfillment of needs, and objective factors.The philosophy of life outlined in this paper tries to measure the global quality of life with questions derived from the integrative theory of the quality of life. The IQOL theory is an overall theory or meta-theory encompassing eight more factual theories in a subjective-existential-objective spectrum. Other philosophies of life can stress other aspects of life, but by this notion of introducing such an existential depth into the health and social sciences, we believe to have taken a necessary step towards a new humility and respect for the richness and complexity of life.

  8. Mood effects on memory and executive control in a real-life situation.

    Science.gov (United States)

    Lagner, Prune; Kliegel, Matthias; Phillips, Louise H; Ihle, Andreas; Hering, Alexandra; Ballhausen, Nicola; Schnitzspahn, Katharina M

    2015-01-01

    In the laboratory, studies have shown an inconsistent pattern of whether, and how, mood may affect cognitive functions indicating both mood-related enhancement as well as decline. Surprisingly, little is known about whether there are similar effects in everyday life. Hence, the present study aimed to investigate possible mood effects on memory and executive control in a real-life situation. Mood effects were examined in the context of winning in a sports competition. Sixty-one male handball players were tested with an extensive cognitive test battery (comprising memory and executive control) both after winning a match and after training as neutral baseline. Mood differed significantly between the two testing situations, while physiological arousal and motivation were comparable. Results showed lowered performance after the win compared with training in selected cognitive measures. Specifically, short-term and episodic memory performance was poorer following a win, whereas executive control performance was unaffected by condition. Differences in memory disappeared when emotional states after the match were entered as covariates into the initial analyses. Thus, findings suggest mood-related impairments in memory, but not in executive control processes after a positive real-life event.

  9. Importance of leadership in cardiac arrest situations: from simulation to real life and back.

    Science.gov (United States)

    Hunziker, Sabnina; Tschan, Franziska; Semmer, Norbert K; Marsch, Stephan

    2013-04-18

    The 2010 American Heart Association guidelines now recommend leadership training in Advanced Cardiac Life Support courses. In this review we provide a comprehensive summary of data derived from clinical studies that investigated the importance of leadership in cardiopulmonary resuscitation (CPR). Only a few, mostly observational, studies have been conducted under real-life conditions because of the high heterogeneity of the situations, difficulties in capturing the initial phase of CPR, and ethical issues. Well-controlled studies in the human simulator can fill existing gaps and provide important insights. High-fidelity video-assisted simulator studies from different research groups have shown that a prolonged process of teambuilding is associated with significant shortcomings in CPR, whereas effective leadership improves team performance. In addition, randomised controlled studies have provided evidence that medical students receiving leadership training subsequently showed improved CPR performance, which was sustained after a follow up of 4 months. In addition, leadership is influenced by gender and other factors such as emotional stress. Future studies are needed to investigate cultural differences and how findings from the simulator can be transferred to real-life situations.

  10. The evolution of "Life": A Metadarwinian integrative approach.

    Science.gov (United States)

    De Loof, Arnold

    2017-01-01

    It is undeniably very logical to first formulate an unambiguous definition of "Life" before engaging in defining the parameters instrumental to Life's evolution. Because nearly everybody assumes, erroneously in my opinion, that catching Life's essence in a single sentence is impossible, this way of thinking remained largely unexplored in evolutionary theory. Upon analyzing what exactly happens at the transition from "still alive" to "just dead," the following definition emerged. What we call "Life" (L) is an activity . It is nothing other than the total sum (∑) of all communication acts (C) executed, at moment t, by entities organized as sender-receiver compartments: L = ∑C Such "living" entities are self-electrifying and talking ( = communicating) aggregates of fossil stardust operating in an environment heavily polluted by toxic calcium. Communication is a multifaceted, complex process that is seldom well explained in introductory textbooks of biology. Communication is instrumental to adaptation because, at the cellular level, any act of communication is in fact a problem-solving act. It can be logically deduced that not Natural Selection itself but communication/problem-solving activity preceding selection is the universal driving force of evolution. This is against what textbooks usually claim, although doubt on the status of Natural Selection as driving force has been around for long. Finally, adopting the sender-receiver with its 2 memory systems (genetic and cognitive, both with their own rules) and 2 types of progeny ("physical children" and "pupils") as the universal unit of architecture and function of all living entities, also enables the seamless integration of cultural and organic evolution, another long-standing tough problem in evolutionary theory. Paraphrasing Theodosius Dobzhansky, the very essence of biology is: "Nothing in biology and evolutionary theory makes sense except in the light of the ability of living matter to communicate, and by

  11. An integrated real-time diagnostic concept using expert systems, qualitative reasoning and quantitative analysis

    International Nuclear Information System (INIS)

    Edwards, R.M.; Lee, K.Y.; Kumara, S.; Levine, S.H.

    1989-01-01

    An approach for an integrated real-time diagnostic system is being developed for inclusion as an integral part of a power plant automatic control system. In order to participate in control decisions and automatic closed loop operation, the diagnostic system must operate in real-time. Thus far, an expert system with real-time capabilities has been developed and installed on a subsystem at the Experimental Breeder Reactor (EBR-II) in Idaho, USA. Real-time simulation testing of advanced power plant concepts at the Pennsylvania State University has been developed and was used to support the expert system development and installation at EBR-II. Recently, the US National Science Foundation (NSF) and the US Department of Energy (DOE) have funded a Penn State research program to further enhance application of real-time diagnostic systems by pursuing implementation in a distributed power plant computer system including microprocessor based controllers. This paper summarizes past, current, planned, and possible future approaches to power plant diagnostic systems research at Penn State. 34 refs., 9 figs

  12. 3D Interactions between Virtual Worlds and Real Life in an E-Learning Community

    Directory of Open Access Journals (Sweden)

    Ulrike Lucke

    2011-01-01

    Full Text Available Virtual worlds became an appealing and fascinating component of today's internet. In particular, the number of educational providers that see a potential for E-Learning in such new platforms increases. Unfortunately, most of the environments and processes implemented up to now do not exceed a virtual modelling of real-world scenarios. In particular, this paper shows that Second Life can be more than just another learning platform. A flexible and bidirectional link between the reality and the virtual world enables synchronous and seamless interaction between users and devices across both worlds. The primary advantages of this interconnection are a spatial extension of face-to-face and online learning scenarios and a closer relationship between virtual learners and the real world.

  13. REAL-LIFE ACTIVITIES: BOOSTING MY STUDENTS’ AWARENESS OF HONESTY IN CREATING GENRE

    Directory of Open Access Journals (Sweden)

    Rr. Dewi Wahyu Mustikasari

    2017-04-01

    Full Text Available My students was strugled to write genre without copypasting sentences or texts from the internet. On the other hand, it was a huge challange for me to teach five big writing classes. Each class consisted of 25-30 students who tended (mostly collecting unoriginal writing works. This paper discusses the real-life activities that can be used to enhance my students’ aweareness of honesty in creating genre. My students must write some genres namely recount, descriptive (optional, spoof (optional, procedure, hortatory (optional and analytical exposition (optional text. I also took some benefits of ICT to equip the learning process. Browsing and experiencing the menu of premierskills.britishcouncil.org were the real-life activities that explore their personal memories to be told as the recount text. Then they defined the feature of one of the menu of the previous website to be informed as the descriptive text. Furthermore, they wrote their personal funny experiences which were related to the Indonesian culture as the spoof text. The procedure text can be produced by exploring the daily activities in the pictures such as how to make a cup of tea/coffee, cook a sunny side-up egg, insert sim card into mobile phone, etc. Next, my students visited the tourism and public places in Salatiga, and they observed the strength and weekness of those places as the production of hortatory or analytical exposition text. The real-life activities were able to foster my students’ awareness of honesty. It was fantastic that my students were able to create the genre honestly.

  14. Electrochemical dehalogenisation of chlorinated aromatics - from model substances to practice-relevant ''real life'' samples

    International Nuclear Information System (INIS)

    Voss, I.; Altrogge, M.; Francke, W.

    1993-01-01

    Building on methods for the dehalogenisation of chlorinated benzoles known from the literature, an investigation was carried out whether polychlorinated biphenyls, dibenzo furane and dibenzo-p-dioxin can be dehalogenated electrochemically. The experiments were carried out with pure substances and transferred to mixed substances (real life samples). The investigations showed that both pure substances and complex mixtures can be dehalogenated without problems. Even in the presence of a clear oil matrix (e.g.: Oil trickled through a deposit), dehalogenisation of the xenobiotica present is possible. First attempts at 'scaling up' show that the method is also suitable in principle, for the disposal of large quantities of contaminated liquids. (BBR) [de

  15. Dried blood spots, valid screening for viral hepatitis and human immunodeficiency virus in real-life

    DEFF Research Database (Denmark)

    Mössner, Belinda K; Staugaard, Benjamin; Jensen, Janne

    2016-01-01

    AIM: To detect chronic hepatitis B (CHB), chronic hepatitis C (CHC) and human immunodeficiency virus (HIV) infections in dried blood spot (DBS) and compare these samples to venous blood sampling in real-life. METHODS: We included prospective patients with known viral infections from drug treatment......, but correctly classified 95% of the anti-HCV-positive patients with chronic and past infections. Anti-HBc and anti-HBS showed low sensitivity in DBS (68% and 42%). CONCLUSION: DBS sampling, combined with an automated analysis system, is a feasible screening method to diagnose chronic viral hepatitis and HIV...

  16. Real/Life: New British Art and the Reception of Contemporary British Art in Japan

    Directory of Open Access Journals (Sweden)

    Kajiya Kenji

    2016-07-01

    Full Text Available This essay explores the ways in which the exhibition Real/Life: New British Art was conceived and received in Japan, where contemporary British art has been shown since the 1960s. Taking place at five museums in the country between 1998 and 1999, the exhibition aimed to showhow British artists in the 1990s struggled with realities, internal and external, but its response was not as satisfactory as was expected. The essay examines the exhibition as a turning point for the transformation of exhibition culture in Japan from nationally themed exhibitions to showcases of contemporary art in the global context.

  17. Life cycle integrated thermoeconomic assessment method for energy conversion systems

    International Nuclear Information System (INIS)

    Kanbur, Baris Burak; Xiang, Liming; Dubey, Swapnil; Choo, Fook Hoong; Duan, Fei

    2017-01-01

    Highlights: • A new LCA integrated thermoeconomic approach is presented. • The new unit fuel cost is found 4.8 times higher than the classic method. • The new defined parameter increased the sustainability index by 67.1%. • The case studies are performed for countries with different CO 2 prices. - Abstract: Life cycle assessment (LCA) based thermoeconomic modelling has been applied for the evaluation of energy conversion systems since it provided more comprehensive and applicable assessment criteria. This study proposes an improved thermoeconomic method, named as life cycle integrated thermoeconomic assessment (LCiTA), which combines the LCA based enviroeconomic parameters in the production steps of the system components and fuel with the conventional thermoeconomic method for the energy conversion systems. A micro-cogeneration system is investigated and analyzed with the LCiTA method, the comparative studies show that the unit cost of fuel by using the LCiTA method is 3.8 times higher than the conventional thermoeconomic model. It is also realized that the enviroeconomic parameters during the operation of the system components do not have significant impacts on the system streams since the exergetic parameters are dominant in the thermoeconomic calculations. Moreover, the improved sustainability index is found roundly 67.2% higher than the previously defined sustainability index, suggesting that the enviroeconomic and thermoeconomic parameters decrease the impact of the exergy destruction in the sustainability index definition. To find the feasible operation conditions for the micro-cogeneration system, different assessment strategies are presented. Furthermore, a case study for Singapore is conducted to see the impact of the forecasted carbon dioxide prices on the thermoeconomic performance of the micro-cogeneration system.

  18. The integrative power of sport: Imagined and real effects of sport events on multicultural integration

    NARCIS (Netherlands)

    Müller, F.; van Zoonen, L.; de Roode, L.

    2008-01-01

    Despite a lack of supporting empirical evidence, the belief that sport participation can be used to address a wide range of social problems remains popular. In this study we explored ways in which the social-integration value of sport participation was constructed by participants in an Amsterdam

  19. Speech Recognition in Real-Life Background Noise by Young and Middle-Aged Adults with Normal Hearing

    OpenAIRE

    Lee, Ji Young; Lee, Jin Tae; Heo, Hye Jeong; Choi, Chul-Hee; Choi, Seong Hee; Lee, Kyungjae

    2015-01-01

    Background and Objectives People usually converse in real-life background noise. They experience more difficulty understanding speech in noise than in a quiet environment. The present study investigated how speech recognition in real-life background noise is affected by the type of noise, signal-to-noise ratio (SNR), and age. Subjects and Methods Eighteen young adults and fifteen middle-aged adults with normal hearing participated in the present study. Three types of noise [subway noise, vacu...

  20. Stroke and quality of life: an integrative review

    Directory of Open Access Journals (Sweden)

    Mary Ângela Canuto

    2015-04-01

    Full Text Available Objetivo:Investigar os domínios da qualidade de vida mais afetados em sobreviventes de acidente vascular cerebral de acordo com instrumentos específicos de avaliação. Métodos: Trata-se de revisão integrativa nas bases MEDLINE, Lilacs e Cinahl, nas quais foram selecionados sete artigos. Resultados: Os artigos foram agrupados conforme a escala utilizada: na Stroke Impact Scale, os domínios mais afetados foram função física, participação social, emoção. Na Stroke Specific Quality of Life Scale, foram trabalho/produtividade, relações familiares e sociais, modo de pensar, energia, linguagem.Nohealth-related quality of life in stroke patients questionnaire, foram interação ecossocial, intelectual, físico.Conclusão: A qualidade de vida de sobreviventes é prejudicada de forma global e multifacetada. Há necessidade de ampliar as pesquisas com instrumentos específicos de medida, pois estes avaliam domínios de especial interesse, demonstrando um perfil integral das condições funcionais e psicossociais dos sobreviventes, e assim, contribuindo para melhoria da atenção à sua saúde.

  1. Integrated manure utilization system life-cycle value assessment

    Energy Technology Data Exchange (ETDEWEB)

    Row, J.; Neabel, D. [Pembina Inst. for Appropriate Development, Drayton Valley, AB (Canada)

    2005-10-15

    A life-cycle assessment of the Alberta Research Council (ARC) and Highmark Renewables' development of an integrated manure utilization system (IMUS) were presented. The assessment focused on an evaluation of factors of primary importance to government, investors and the livestock industry. IMUS technology uses manure as a resource to produce electricity, heat, bio-based fertilizer and reusable water. Results of the assessment indicated that IMUS plants have the potential to be financially viable if a power purchase of $90 MWh on average can be purchased from a 30,000 head livestock operation. A capital cost of under $11 million is necessary, and an established biofertilizer price of $50 per tonne should be established. An IMUS plant was estimated to reduce life-cycle greenhouse gas emissions by 70 to 80 per cent when compared to land spreading. Reductions are accomplished through displacing electricity from the provincial grid and reducing nitrous oxide (N{sub 2}O) emissions from spreading of manure The IMUS plants lessen environment impacts by reducing the extraction and consumption of non-renewable resources, and by displacing an estimated 11,700 GJ of coal and natural gas per 1000 head of cattle per year. In addition, various pathogens within manure are eliminated. The plants have the potential to eliminate the environmental hazards associated with the disposal of deadstock. The systems reduce manure odour, lessen truck traffic and are expected to contribute to rural economic diversification. Barriers to further implementation of IMUS were discussed, as well as emerging opportunities for IMUS developers. It was concluded that the initial assessments of the IMUS were positive. Further investigation is needed to determine actual life-cycle performance of the operations. 18 refs., 3 tabs., 3 figs.

  2. Loose and Tight GNSS/INS Integrations: Comparison of Performance Assessed in Real Urban Scenarios.

    Science.gov (United States)

    Falco, Gianluca; Pini, Marco; Marucco, Gianluca

    2017-01-29

    Global Navigation Satellite Systems (GNSSs) remain the principal mean of positioning in many applications and systems, but in several types of environment, the performance of standalone receivers is degraded. Although many works show the benefits of the integration between GNSS and Inertial Navigation Systems (INSs), tightly-coupled architectures are mainly implemented in professional devices and are based on high-grade Inertial Measurement Units (IMUs). This paper investigates the performance improvements enabled by the tight integration, using low-cost sensors and a mass-market GNSS receiver. Performance is assessed through a series of tests carried out in real urban scenarios and is compared against commercial modules, operating in standalone mode or featuring loosely-coupled integrations. The paper describes the developed tight-integration algorithms with a terse mathematical model and assesses their efficacy from a practical perspective.

  3. Integration of domain and resource-based reasoning for real-time control in dynamic environments

    Science.gov (United States)

    Morgan, Keith; Whitebread, Kenneth R.; Kendus, Michael; Cromarty, Andrew S.

    1993-01-01

    A real-time software controller that successfully integrates domain-based and resource-based control reasoning to perform task execution in a dynamically changing environment is described. The design of the controller is based on the concept of partitioning the process to be controlled into a set of tasks, each of which achieves some process goal. It is assumed that, in general, there are multiple ways (tasks) to achieve a goal. The controller dynamically determines current goals and their current criticality, choosing and scheduling tasks to achieve those goals in the time available. It incorporates rule-based goal reasoning, a TMS-based criticality propagation mechanism, and a real-time scheduler. The controller has been used to build a knowledge-based situation assessment system that formed a major component of a real-time, distributed, cooperative problem solving system built under DARPA contract. It is also being employed in other applications now in progress.

  4. The Real-Time Monitoring Service Platform for Land Supervision Based on Cloud Integration

    Science.gov (United States)

    Sun, J.; Mao, M.; Xiang, H.; Wang, G.; Liang, Y.

    2018-04-01

    Remote sensing monitoring has become the important means for land and resources departments to strengthen supervision. Aiming at the problems of low monitoring frequency and poor data currency in current remote sensing monitoring, this paper researched and developed the cloud-integrated real-time monitoring service platform for land supervision which enhanced the monitoring frequency by acquiring the domestic satellite image data overall and accelerated the remote sensing image data processing efficiency by exploiting the intelligent dynamic processing technology of multi-source images. Through the pilot application in Jinan Bureau of State Land Supervision, it has been proved that the real-time monitoring technical method for land supervision is feasible. In addition, the functions of real-time monitoring and early warning are carried out on illegal land use, permanent basic farmland protection and boundary breakthrough in urban development. The application has achieved remarkable results.

  5. Work and personal life boundary management: boundary strength, work/personal life balance, and the segmentation-integration continuum.

    Science.gov (United States)

    Bulger, Carrie A; Matthews, Russell A; Hoffman, Mark E

    2007-10-01

    While researchers are increasingly interested in understanding the boundaries surrounding the work and personal life domains, few have tested the propositions set forth by theory. Boundary theory proposes that individuals manage the boundaries between work and personal life through processes of segmenting and/or integrating the domains. The authors investigated boundary management profiles of 332 workers in an investigation of the segmentation-integration continuum. Cluster analysis indicated consistent clusters of boundary management practices related to varying segmentation and integration of the work and personal life domains. But, the authors suggest that the segmentation-integration continuum may be more complicated. Results also indicated relationships between boundary management practices and work-personal life interference and work-personal life enhancement. Less flexible and more permeable boundaries were related to more interference, while more flexible and more permeable boundaries were related to more enhancement.

  6. Integrating the Integrated Care Organisation – Optimising Resources, Operations, and Services to Create Real Value

    OpenAIRE

    Yap, Jason

    2018-01-01

    Introduction: Implementing Integrated Care to promote and protect the health of organisations is massively complex. Historically, healthcare practitioners thought in terms of single patient acute care encounters within healthcare facilities, and seek to help the patient become “apparently well” again. With an ageing population, multiple morbidities, complex socioeconomic factors, and increasing costs, we must now reconsider our paradigms.In Singapore, the focus has been on our “models of care...

  7. Critical Care Nurses Inadequately Assess SAPS II Scores of Very Ill Patients in Real Life

    Directory of Open Access Journals (Sweden)

    Andreas Perren

    2012-01-01

    Full Text Available Background. Reliable ICU severity scores have been achieved by various healthcare workers but nothing is known regarding the accuracy in real life of severity scores registered by untrained nurses. Methods. In this retrospective multicentre audit, three reviewers independently reassessed 120 SAPS II scores. Correlation and agreement of the sum-scores/variables among reviewers and between nurses and the reviewers’ gold standard were assessed globally and for tertiles. Bland and Altman (gold standard—nurses of sum scores and regression of the difference were determined. A logistic regression model identifying risk factors for erroneous assessments was calculated. Results. Correlation for sum scores among reviewers was almost perfect (mean ICC = 0.985. The mean (±SD nurse-registered SAPS II sum score was 40.3±20.2 versus 44.2±24.9 of the gold standard (32 points scores. The lowest agreement was found in high SAPS II tertiles for haemodynamics (k = 0.45–0.51. Conclusions. In real life, nurse-registered SAPS II scores of very ill patients are inaccurate. Accuracy of scores was not associated with nurses’ characteristics.

  8. Images of eyes enhance investments in a real-life public good.

    Directory of Open Access Journals (Sweden)

    Damien Francey

    Full Text Available A key issue in cooperation research is to determine the conditions under which individuals invest in a public good. Here, we tested whether cues of being watched increase investments in an anonymous public good situation in real life. We examined whether individuals would invest more by removing experimentally placed garbage (paper and plastic bottles from bus stop benches in Geneva in the presence of images of eyes compared to controls (images of flowers. We provided separate bins for each of both types of garbage to investigate whether individuals would deposit more items into the appropriate bin in the presence of eyes. The treatment had no effect on the likelihood that individuals present at the bus stop would remove garbage. However, those individuals that engaged in garbage clearing, and were thus likely affected by the treatment, invested more time to do so in the presence of eyes. Images of eyes had a direct effect on behaviour, rather than merely enhancing attention towards a symbolic sign requesting removal of garbage. These findings show that simple images of eyes can trigger reputational effects that significantly enhance on non-monetary investments in anonymous public goods under real life conditions. We discuss our results in the light of previous findings and suggest that human social behaviour may often be shaped by relatively simple and potentially unconscious mechanisms instead of very complex cognitive capacities.

  9. Desiderio e scrittura in "The Real Life of Sebastian Knight" di Vladimir Nabokov

    Directory of Open Access Journals (Sweden)

    Valeria Invernizzi

    2014-12-01

    This paper examines, from a psychoanalytic standpoint, the intersection between identity and writing in the novel The Real Life of Sebastian Knight (1941 by Vladimir Nabokov. In particular, in the wake of Freud and Lacan, the following contribution will take the notions of desire, signifier, and the process of sublimation involved in artistic creation as interpretative devices. The main focus of the analysis will be the relationship between the two half-brothers of the novel, V (the narrator and Sebastian. First, I will show that Sebastian Knight holds the role of the object of desire for the characters who have established a close relationship with him and, in particular, for V. Secondly, the paper will be devoted to the analysis of the trauma experienced by the characters because of Sebastian's death, with a particular focus on the narrator's mourning through writing (the fictional biography we read in the novel; in the end, I will give evidence of the so-called signifier’s fallacy, crucial episodes in which the narrator can experience an insight into the truth of desire. Because of the not negligible question of the fictional paternity of The Real Life and the equally essential matter of V’s ‘stylistic touch’, metaliterary aspects of the novel will also be part of the following reading of the text.

  10. Optimal Energy Management for the Integrated Power and Gas Systems via Real-time Pricing

    DEFF Research Database (Denmark)

    Shu, KangAn; Ai, Xiaomeng; Wen, Jinyu

    2018-01-01

    This work proposed a bi-level formulation for energy management in the integrated power and natural gas system via real-time price signals. The upper-level problem minimizes the operational cost, in which dynamic electricity price and dynamic gas tariff are proposed. The lower level problem...... and P2Gs plants follow the system operator’s preferences such as wind power accommodation, mitigation of unsupplied load and relieving the network congestion....

  11. Integration of plant life management in operation and maintenance

    International Nuclear Information System (INIS)

    Hutin, Jean-Pierre

    2002-01-01

    Full text: 1 - INTRODUCTION. Electricite de France is now operating 58 PWR nuclear power plants which produce 75% of french electricity. Besides maintaining safety and availability on a routine basis, it is outmost important to protect the investment. Indeed, such an asset is a tremendous advantage just as the company is going to face the new european electricity market. That is the reason why EDF is devoting important effort to implement ageing management as an integral part of operation and maintenance programs. But it must be recognized that NPP lifetime is not threatened only by component-related problems: other less technical issues must be seriously considered like industrial support, information system, skilled people, public acceptance, etc. 2 - LIFE MANAGEMENT POLICY. In France, there is no limited licensing period for NPPs. The life management policy of nuclear power plants is based on three principles: - safe and cost-effective operation, looking for excellence in daily activities, with an effective experience feedback organisation taking advantage of the high level of standardization of the units, - every ten years, a new set of safety standards, a complete review of each facility and an upgrading of its safety level through appropriate modifications while maintaining unit standardization in all the fleet, - a Life Management Program, at corporate level, which permanently scrutinizes operation and maintenance activities to identify decisions which could impair plant lifetime and which surveys research and development programs related to ageing phenomenon understanding. 3 - INTEGRATION OF LIFETIME CONCERN IN O and M ACTIVITIES. It is outmost important to take in account lifetime concern in daily operation and maintenance activities and this must be done as early as possible in plant life. Even though sophisticated assessments require engineering capacity, many good ideas may arise from plant staff. For that reason, increasing lifetime awareness of plant

  12. Architecture for an integrated real-time air combat and sensor network simulation

    Science.gov (United States)

    Criswell, Evans A.; Rushing, John; Lin, Hong; Graves, Sara

    2007-04-01

    An architecture for an integrated air combat and sensor network simulation is presented. The architecture integrates two components: a parallel real-time sensor fusion and target tracking simulation, and an air combat simulation. By integrating these two simulations, it becomes possible to experiment with scenarios in which one or both sides in a battle have very large numbers of primitive passive sensors, and to assess the likely effects of those sensors on the outcome of the battle. Modern Air Power is a real-time theater-level air combat simulation that is currently being used as a part of the USAF Air and Space Basic Course (ASBC). The simulation includes a variety of scenarios from the Vietnam war to the present day, and also includes several hypothetical future scenarios. Modern Air Power includes a scenario editor, an order of battle editor, and full AI customization features that make it possible to quickly construct scenarios for any conflict of interest. The scenario editor makes it possible to place a wide variety of sensors including both high fidelity sensors such as radars, and primitive passive sensors that provide only very limited information. The parallel real-time sensor network simulation is capable of handling very large numbers of sensors on a computing cluster of modest size. It can fuse information provided by disparate sensors to detect and track targets, and produce target tracks.

  13. Integration of real-time 3D capture, reconstruction, and light-field display

    Science.gov (United States)

    Zhang, Zhaoxing; Geng, Zheng; Li, Tuotuo; Pei, Renjing; Liu, Yongchun; Zhang, Xiao

    2015-03-01

    Effective integration of 3D acquisition, reconstruction (modeling) and display technologies into a seamless systems provides augmented experience of visualizing and analyzing real objects and scenes with realistic 3D sensation. Applications can be found in medical imaging, gaming, virtual or augmented reality and hybrid simulations. Although 3D acquisition, reconstruction, and display technologies have gained significant momentum in recent years, there seems a lack of attention on synergistically combining these components into a "end-to-end" 3D visualization system. We designed, built and tested an integrated 3D visualization system that is able to capture in real-time 3D light-field images, perform 3D reconstruction to build 3D model of the objects, and display the 3D model on a large autostereoscopic screen. In this article, we will present our system architecture and component designs, hardware/software implementations, and experimental results. We will elaborate on our recent progress on sparse camera array light-field 3D acquisition, real-time dense 3D reconstruction, and autostereoscopic multi-view 3D display. A prototype is finally presented with test results to illustrate the effectiveness of our proposed integrated 3D visualization system.

  14. An Anomalous Noise Events Detector for Dynamic Road Traffic Noise Mapping in Real-Life Urban and Suburban Environments

    Directory of Open Access Journals (Sweden)

    Joan Claudi Socoró

    2017-10-01

    Full Text Available One of the main aspects affecting the quality of life of people living in urban and suburban areas is their continued exposure to high Road Traffic Noise (RTN levels. Until now, noise measurements in cities have been performed by professionals, recording data in certain locations to build a noise map afterwards. However, the deployment of Wireless Acoustic Sensor Networks (WASN has enabled automatic noise mapping in smart cities. In order to obtain a reliable picture of the RTN levels affecting citizens, Anomalous Noise Events (ANE unrelated to road traffic should be removed from the noise map computation. To this aim, this paper introduces an Anomalous Noise Event Detector (ANED designed to differentiate between RTN and ANE in real time within a predefined interval running on the distributed low-cost acoustic sensors of a WASN. The proposed ANED follows a two-class audio event detection and classification approach, instead of multi-class or one-class classification schemes, taking advantage of the collection of representative acoustic data in real-life environments. The experiments conducted within the DYNAMAP project, implemented on ARM-based acoustic sensors, show the feasibility of the proposal both in terms of computational cost and classification performance using standard Mel cepstral coefficients and Gaussian Mixture Models (GMM. The two-class GMM core classifier relatively improves the baseline universal GMM one-class classifier F1 measure by 18.7% and 31.8% for suburban and urban environments, respectively, within the 1-s integration interval. Nevertheless, according to the results, the classification performance of the current ANED implementation still has room for improvement.

  15. Integration of multidisciplinary technologies for real time target visualization and verification for radiotherapy.

    Science.gov (United States)

    Chang, Wen-Chung; Chen, Chin-Sheng; Tai, Hung-Chi; Liu, Chia-Yuan; Chen, Yu-Jen

    2014-01-01

    The current practice of radiotherapy examines target coverage solely from digitally reconstructed beam's eye view (BEV) in a way that is indirectly accessible and that is not in real time. We aimed to visualize treatment targets in real time from each BEV. The image data of phantom or patients from ultrasound (US) and computed tomography (CT) scans were captured to perform image registration. We integrated US, CT, US/CT image registration, robotic manipulation of US, a radiation treatment planning system, and a linear accelerator to constitute an innovative target visualization system. The performance of this algorithm segmented the target organ in CT images, transformed and reconstructed US images to match each orientation, and generated image registration in real time mode with acceptable accuracy. This image transformation allowed physicians to visualize the CT image-reconstructed target via a US probe outside the BEV that was non-coplanar to the beam's plane. It allowed the physicians to remotely control the US probe that was equipped on a robotic arm to dynamically trace and real time monitor the coverage of the target within the BEV during a simulated beam-on situation. This target visualization system may provide a direct remotely accessible and real time way to visualize, verify, and ensure tumor targeting during radiotherapy.

  16. 'Real-life' effectiveness studies of omalizumab in adult patients with severe allergic asthma: systematic review.

    Science.gov (United States)

    Abraham, I; Alhossan, A; Lee, C S; Kutbi, H; MacDonald, K

    2016-05-01

    We reviewed 24 'real-life' effectiveness studies of omalizumab in the treatment of severe allergic asthma that included 4117 unique patients from 32 countries with significant heterogeneity in patients, clinicians and settings. The evidence underscores the short- and long-term benefit of anti-IgE therapy in terms of the following: improving lung function; achieving asthma control and reducing symptomatology, severe exacerbations and associated work/school days lost; reducing healthcare resource utilizations, in particular hospitalizations, hospital lengths of stay and accident specialist or emergency department visits; reducing or discontinuing other asthma medications; and improving quality of life - thus confirming, complementing and extending evidence from randomized trials. Thus, omalizumab therapy is associated with signal improvements across the full objective and subjective burden of illness chain of severe allergic asthma. Benefits of omalizumab may extend up to 2-4 years, and the majority of omalizumab-treated patients may benefit for many years. Omalizumab has positive short- and long-term safety profiles similar to what is known from randomized clinical trials. Initiated patients should be monitored for treatment response at 16 weeks. Those showing positive response at that time are highly likely to show sustained treatment response and benefit in terms of clinical, quality of life and health resource utilization outcomes. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  17. The Other Side of the Screen - Simultaneously maintaining social relationships in real life and on social media

    OpenAIRE

    Gruenke, Solveig Wiland

    2017-01-01

    Social media as a social concept is becoming a prominent fixture in social life and is taking on a significant increase in social relevance, both academically and in popular discourse. The academic research is often focused on either the online content itself or the macro societal implications, more than the real-life social aspect of social media. People using social media are now simultaneously producing content about their life online, whilst they are, in fact, living it. The new social fe...

  18. A Comparison of Online Social Networks and Real-Life Social Networks: A Study of Sina Microblogging

    Directory of Open Access Journals (Sweden)

    Dayong Zhang

    2014-01-01

    Full Text Available Online social networks appear to enrich our social life, which raises the question whether they remove cognitive constraints on human communication and improve human social capabilities. In this paper, we analyze the users' following and followed relationships based on the data of Sina Microblogging and reveal several structural properties of Sina Microblogging. Compared with real-life social networks, our results confirm some similar features. However, Sina Microblogging also shows its own specialties, such as hierarchical structure and degree disassortativity, which all mark a deviation from real-life social networks. The low cost of the online network forms a broader perspective, and the one-way link relationships make it easy to spread information, but the online social network does not make too much difference in the creation of strong interpersonal relationships. Finally, we describe the mechanisms for the formation of these characteristics and discuss the implications of these structural properties for the real-life social networks.

  19. Quality of life improvement in HIV-1 patients treated with raltegravir in a real-life observational study: RACING.

    Science.gov (United States)

    Spire, Bruno; Nait-Ighil, Lella; Pugliese, Pascal; Poizot-Martin, Isabelle; Jullien, Vincent; Marcelin, Anne-Geneviève; Billaud, Eric

    2017-01-01

    Good efficacy and safety of raltegravir in person living with HIV was demonstrated in clinical trials over five years, but real-life data, particularly about quality of life (QoL), are lacking. QoL was evaluated over time in adult patients first treated or switched to regimens containing raltegravir in an observational cohort study. Patient QoL was evaluated using the Fatigue Impact Scale (FIS) and the HIV Symptom Index (HSI). Data were collected at baseline and at 1, 3, 6, 12, 18, and 24 months. Baseline FIS and HSI subscores were compared with the scores at each visit using the paired Wilcoxon test. The impact of time, sociodemographic and medical variables upon patient-perceived fatigue and symptoms was also assessed using mixed multivariate models. From baseline, all FIS and HSI subscores improved significantly after one month of treatment. In addition, psychosocial FIS subscores and both the frequency of bothersome symptoms and HSI subscores improved significantly at each visit. Physical FIS subscores also improved significantly, except at month 18, whereas both cognitive and total FIS subscores improved only after 6 months and 24 months, respectively. In multivariate analysis, employment was independently associated over time with improved improvement in both FIS and HSI subscores. Patient QoL improved significantly over a 24-month period of treatment with a raltegravir-containing regimen. FIS and HSI are sensitive tools to measure the impact of new antiretroviral combinations on a patient's perception of QoL.

  20. Double path-integral migration velocity analysis: a real data example

    International Nuclear Information System (INIS)

    Costa, Jessé C; Schleicher, Jörg

    2011-01-01

    Path-integral imaging forms an image with no knowledge of the velocity model by summing over the migrated images obtained for a set of migration velocity models. Double path-integral imaging migration extracts the stationary velocities, i.e. those velocities at which common-image gathers align horizontally, as a byproduct. An application of the technique to a real data set demonstrates that quantitative information about the time migration velocity model can be determined by double path-integral migration velocity analysis. Migrated images using interpolations with different regularizations of the extracted velocities prove the high quality of the resulting time-migration velocity information. The so-obtained velocity model can then be used as a starting model for subsequent velocity analysis tools like migration tomography or other tomographic methods

  1. Structural Equation Modeling on Life-world Integration in People with Severe Burns

    Directory of Open Access Journals (Sweden)

    Gyeong Suk Lee, PhD, RN

    2013-09-01

    Conclusion: Physical function should be directly improved to adjust to life-world integration. A comprehensive integration approach is also necessary to help people with severe burns successfully return to society.

  2. Integrating and Visualizing Tropical Cyclone Data Using the Real Time Mission Monitor

    Science.gov (United States)

    Goodman, H. Michael; Blakeslee, Richard; Conover, Helen; Hall, John; He, Yubin; Regner, Kathryn

    2009-01-01

    The Real Time Mission Monitor (RTMM) is a visualization and information system that fuses multiple Earth science data sources, to enable real time decision-making for airborne and ground validation experiments. Developed at the NASA Marshall Space Flight Center, RTMM is a situational awareness, decision-support system that integrates satellite imagery, radar, surface and airborne instrument data sets, model output parameters, lightning location observations, aircraft navigation data, soundings, and other applicable Earth science data sets. The integration and delivery of this information is made possible using data acquisition systems, network communication links, network server resources, and visualizations through the Google Earth virtual globe application. RTMM is extremely valuable for optimizing individual Earth science airborne field experiments. Flight planners, scientists, and managers appreciate the contributions that RTMM makes to their flight projects. A broad spectrum of interdisciplinary scientists used RTMM during field campaigns including the hurricane-focused 2006 NASA African Monsoon Multidisciplinary Analyses (NAMMA), 2007 NOAA-NASA Aerosonde Hurricane Noel flight, 2007 Tropical Composition, Cloud, and Climate Coupling (TC4), plus a soil moisture (SMAP-VEX) and two arctic research experiments (ARCTAS) in 2008. Improving and evolving RTMM is a continuous process. RTMM recently integrated the Waypoint Planning Tool, a Java-based application that enables aircraft mission scientists to easily develop a pre-mission flight plan through an interactive point-and-click interface. Individual flight legs are automatically calculated "on the fly". The resultant flight plan is then immediately posted to the Google Earth-based RTMM for interested scientists to view the planned flight track and subsequently compare it to the actual real time flight progress. We are planning additional capabilities to RTMM including collaborations with the Jet Propulsion

  3. [Integrated evaluation of circular agriculture system: a life cycle perspective].

    Science.gov (United States)

    Liang, Long; Chen, Yuan-Quan; Gao, Wang-Sheng

    2010-11-01

    For the point of view that recycling economy system is one of ways to achieve the low-carbon economy, we have made an evaluation on a typical circular agriculture duck industry in Hunan Province, China, through improving the framework of life cycle assessment (LCA). The analysis indicated that the consumption of non-renewable resources, land and water were 48.629 MJ, 2.36 m2 and 1 321.41 kg, while the potential greenhouse gas (GHGs), acidification, eutrophication, human toxicity, freshwater ecotoxicity and terrestrial ecotoxicity were 11 543.26 g (CO2 eq), 52.36g (SO2eq), 25.83g (PO4eq), 1.26, 60.74 and 24.65 g (1,4-DCBeq), respectively. The potential damage of aquatic eutrophication, freshwater ecotoxicity and terrestrial ecotoxicity was more serious than that of GHGs. Main results were following: i. the circular agricultural chain promoted the principle of "moderate circulation", which based on the traditional production methods; ii. circular agriculture could not blindly pursue low carbon development. Instead, soil and biological carbon sequestration should be considered, in addition to reducing carbon emissions; iii. circular economy and circular agriculture should take other potential environmental impacts into account such as acidification, eutrophication and ecotoxicity,with the exception to carbon emissions,to developed integrated system assessment; iv. LCA could provide a comprehensive assessment of circular agriculture, and it was worth of further study.

  4. Integration of multidisciplinary technologies for real time target visualization and verification for radiotherapy

    Directory of Open Access Journals (Sweden)

    Chang WC

    2014-06-01

    Full Text Available Wen-Chung Chang,1,* Chin-Sheng Chen,2,* Hung-Chi Tai,3 Chia-Yuan Liu,4,5 Yu-Jen Chen3 1Department of Electrical Engineering, National Taipei University of Technology, Taipei, Taiwan; 2Graduate Institute of Automation Technology, National Taipei University of Technology, Taipei, Taiwan; 3Department of Radiation Oncology, Mackay Memorial Hospital, Taipei, Taiwan; 4Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan; 5Department of Medicine, Mackay Medical College, New Taipei City, Taiwan  *These authors contributed equally to this work Abstract: The current practice of radiotherapy examines target coverage solely from digitally reconstructed beam's eye view (BEV in a way that is indirectly accessible and that is not in real time. We aimed to visualize treatment targets in real time from each BEV. The image data of phantom or patients from ultrasound (US and computed tomography (CT scans were captured to perform image registration. We integrated US, CT, US/CT image registration, robotic manipulation of US, a radiation treatment planning system, and a linear accelerator to constitute an innovative target visualization system. The performance of this algorithm segmented the target organ in CT images, transformed and reconstructed US images to match each orientation, and generated image registration in real time mode with acceptable accuracy. This image transformation allowed physicians to visualize the CT image-reconstructed target via a US probe outside the BEV that was non-coplanar to the beam's plane. It allowed the physicians to remotely control the US probe that was equipped on a robotic arm to dynamically trace and real time monitor the coverage of the target within the BEV during a simulated beam-on situation. This target visualization system may provide a direct remotely accessible and real time way to visualize, verify, and ensure tumor targeting during radiotherapy. Keywords: ultrasound, computerized tomography

  5. Overvoltage Protection of Large Power Transformers - A Real-Life Study Case

    DEFF Research Database (Denmark)

    Bak, Claus Leth; Einarsdottir, K. E.; Andresson, E.

    2008-01-01

    This paper demonstrates the results from a detailed study of the overvoltage protection of a particular 400/150-kV 400-MVA power transformer. The work presented here is based on a real-life power system substation design and data and initiated by Danish TSO Energinet.dk as a consequence of serious...... transformer overvoltage damage. A simulation model for the entire system consisting of overhead line, transformer, surge arrester, and earth grid has been created in PSCAD/EMTDC. The main focus has been put on the earth grid, which has been submodeled in detail in MATLAB using an electromagnetic transient...... exceeded. It is clearly illustrated that the transient performance of the earth grid plays an important role in the overall overvoltage protection system design....

  6. Real life experimental determination of platinum group metals content in automotive catalytic converters

    Science.gov (United States)

    Yakoumis, I.; Moschovi, A. M.; Giannopoulou, I.; Panias, D.

    2018-03-01

    The real life experimental protocol for the preparation of spent automobile catalyst samples for elemental analysis is thoroughly described in the following study. Collection, sorting and dismantling, homogenization and sample preparation for X-Ray fluorescence spectroscopy and Atomic Adsorption Spectroscopy combined with Inductive coupled plasma mass spectrometry are discussed in detail for both ceramic and metallic spent catalysts. The concentrations of Platinum Group Metals (PGMs) in spent catalytic converters are presented based on typical consignments of recycled converters (more than 45,000 pieces) from the Greek Market. The conclusions clearly denoted commercial metallic catalytic foil contains higher PGMs loading than ceramic honeycombs. On the other hand, the total PGMs loading in spent ceramic catalytic converters has been found higher than the corresponding value for the metallic ones.

  7. Cyberbullying in Germany – an exploration of prevalence, overlapping with real life bullying and coping strategies

    Directory of Open Access Journals (Sweden)

    JULIA RIEBEL

    2009-09-01

    Full Text Available A new phenomenon of violence among pupils has been spreading over Europe in the last few years: Cyberbullying, the repeated and intended hurting of weaker schoolmates via modern communication technologies. This study shows (based on a sample of 1987 pupils, that cyberbullying exists in Germany, although the number of incidents is still rather small. It could also be shown, that the pupils who act as cyberbullies are the same as those who bully others in real life. The same overlap was found to be true for the victims. Cyberbullying can therefore be considered a subcategory of ordinary bullying instead of being considered a whole new phenomenon. The exploration of coping strategies showed, that a common factor structure underlies physical, verbal and cyberbullying. Considering the fact that the findings of the study are based on an online questionnaire with restricted representativeness, the results should however be interpreted carefully.

  8. Evaluation of RPL-compliant routing solutions in real-life WSNs

    Directory of Open Access Journals (Sweden)

    Zahariadis Theodore

    2016-01-01

    Full Text Available Wireless Sensor Networks (WSN applications continue to expand and already cover almost all our daily activities improving from security and environmental efficiency to gaming experience. The diverse applications running on top of WSNs have led to the design of an immense number of routing protocols. Few years ago, the IETF standardized the IPv6 routing protocol for low-power and lossy networks (RPL which is based on routing metrics to build communication paths between a source and the destination node. While significant efforts have focused on the design of routing metrics that satisfy the various applications, limited work has been reported on validating their performance using real-life motes. In this paper, we focus on validating the simulation results (obtained through the JSim simulator using TelosB motes for a set of routing metrics that have been proposed in our previous articles.

  9. Can the response to Omalizumab be influenced by treatment duration? A real-life study.

    Science.gov (United States)

    Sposato, Bruno; Scalese, Marco; Latorre, Manuela; Novelli, Federica; Scichilone, Nicola; Milanese, Manlio; Olivieri, Carmela; Perrella, Antonio; Paggiaro, Pierluigi

    2017-06-01

    It is unknown whether Omalizumab effectiveness changes over the course of time. Our retrospective real-life study tried to analyze whether Omalizumab response may be influenced by treatment duration. 340 severe asthmatics treated with Omalizumab for different periods of time were recruited. They were subdivided into 4 groups according to the Omalizumab treatment length: 60 months. Omalizumab treatment results (FEV 1 , exacerbations, ACT, SABA use, asthma control levels, medications used e and ICS doses) were compared. ACT, exacerbations, GINA control levels, ICS doses and SABA use were similar in all groups with different Omalizumab treatment durations. Using a linear regression model, corrected for all confounding variables, a higher significant positive increase in FEV 1 % in subjects treated for 12-24 (β = 9.49; p = 0.034) or 24-60 months (β = 8.56; p = 0.043) was found when compared with subjects treated for a shorter period. Treatment duration was positively associated with a step down of the other associated therapies (OR: 1.013; p = 0.019). This association was more relevant (OR: 4.167; p = 0.005) when we considered Omalizumab treatment duration >60 months compared to the shorter therapy. In particular, the percentage of subjects that were taking Montelukast, LABAs and oral corticosteroids was lower in the group treated with Omalizumab for a longer period of time. In real-life, the positive Omalizumab response remained stable for over 60 months. Long term Omalizumab treatment may lead to a discontinuation of some associated medications and to a slowing down of FEV 1 decline. Copyright © 2017 Elsevier Ltd. All rights reserved.

  10. Real Life Active Gaming Practices of 7-11-Year-Old Children.

    Science.gov (United States)

    Allsop, Susan; Rumbold, Penny Louise Sheena; Debuse, Dorothée; Dodd-Reynolds, Caroline

    2013-12-01

    In the laboratory, active gaming has been shown to increase physical activity levels in children compared with seated media activities. The information is sparse, however, about children's real life active gaming practices, and the laboratory protocols used thus far might not be representative. The purpose of the present study was to establish the sociodemographic characteristics, real life active gaming practices, and reasons for gameplay, to later inform intervention studies. An "Active Gaming Questionnaire" was purposely developed and distributed to 44 7-11-year-old children and their parents. Forty questionnaires were completed and returned. Analysis found 95 percent of the children had access to active gaming consoles "at home." The favorite console was the Nintendo (Kyoto, Japan) Wii™, and the favorite game was Nintendo "Wii Sports." The majority of children frequently played active games against other people. The average reported gameplay time was 81 minutes on 1-2 days per week, usually on a Saturday. More than half of the children (52.5 percent) consumed foods and/or drinks during play, which was significantly associated (P=0.000) with an extended average gameplay time (increased by 25 minutes). The majority of participants (65 percent) considered active gaming to be an alternative form of exercise, and main reasons for active videogame play included for entertainment, health benefits, and the environment. In conclusion, children 9.3±1.4 years old typically play Nintendo "Wii Sports," once or twice per week for 81 minutes. Reported active gameplay time is extended by 25 minutes when food and/or drinks are consumed.

  11. Comparative life cycle assessment of real pilot reactors for microalgae cultivation in different seasons

    International Nuclear Information System (INIS)

    Pérez-López, Paula; De Vree, Jeroen H.; Feijoo, Gumersindo; Bosma, Rouke; Barbosa, Maria J.; Moreira, María Teresa; Wijffels, René H.; Van Boxtel, Anton J.B.; Kleinegris, Dorinde M.M.

    2017-01-01

    Highlights: •Life cycle assessment was used to compare 3 real pilot systems for algae cultivation. •The temperature control system was the main contributor to environmental impacts. •Tubular reactors had lower impacts per unit of biomass produced than open pond. •Meteorological conditions on the reactors played a critical role in LCA results. •Environmental impact reductions of 17–90% were estimated for optimized full-scale reactors. -- Abstract: Microalgae are promising natural resources for biofuels, chemical, food and feed products. Besides their economic potential, the environmental sustainability must be examined. Cultivation has a significant environmental impact that depends on reactor selection and operating conditions. To identify the main environmental bottlenecks for scale-up to industrial facilities this study provides a comparative life cycle assessment (LCA) of open raceway ponds and tubular photobioreactors at pilot scale. The results are based on experimental data from real pilot plants operated in summer, fall and winter at AlgaePARC (Wageningen, The Netherlands). The energy consumption for temperature regulation presented the highest environmental burden. The production of nutrients affected some categories. Despite limited differences compared to the vertical system, the horizontal PBR was found the most efficient in terms of productivity and environmental impact. The ORP was, given the Dutch climatic conditions, only feasible under summer operation. The results highlight the relevance of LCA as a tool for decision-making in process design. Weather conditions and availability of sources for temperature regulation were identified as essential factors for the selection of geographic locations and for microalgal cultivation systems based on environmental criteria. Simulation of large-scale reactors with optimized temperature regulation systems lead to environmental improvements and energy demand reductions ranging from 17% up to 90% for

  12. Real-life compliance and persistence among users of subcutaneous and sublingual allergen immunotherapy.

    Science.gov (United States)

    Kiel, Menno A; Röder, Esther; Gerth van Wijk, Roy; Al, Maiwenn J; Hop, Wim C J; Rutten-van Mölken, Maureen P M H

    2013-08-01

    Subcutaneous allergen immunotherapy (SCIT) and sublingual allergen immunotherapy (SLIT) are safe and effective treatments of allergic rhinitis, but high levels of compliance and persistence are crucial to achieving the desired clinical effects. Our objective was to assess levels and predictors of compliance and persistence among grass pollen, tree pollen, and house dust mite immunotherapy users in real life and to estimate the costs of premature discontinuation. We performed a retrospective analysis of a community pharmacy database from The Netherlands containing data from 6486 patients starting immunotherapy for 1 or more of the allergens of interest between 1994 and 2009. Two thousand seven hundred ninety-six patients received SCIT, and 3690 received SLIT. Time to treatment discontinuation was analyzed and included Cox proportional hazard models with time-dependent covariates, where appropriate. Overall, only 18% of users reached the minimally required duration of treatment of 3 years (SCIT, 23%; SLIT, 7%). Median durations for SCIT and SLIT users were 1.7 and 0.6 years, respectively (P < .001). Other independent predictors of premature discontinuation were prescriber, with patients of general practitioners demonstrating longer persistence than those of allergologists and other medical specialists; single-allergen immunotherapy, lower socioeconomic status; and younger age. Of the persistent patients, 56% were never late in picking up their medication from the pharmacy. Direct medication costs per nonpersistent patient discontinuing in the third year of treatment were €3800, an amount that was largely misspent. Real-life persistence is better in SCIT users than in SLIT users, although it is low overall. There is an urgent need for further identification of potential barriers and measures that will enhance persistence and compliance. Copyright © 2013 American Academy of Allergy, Asthma & Immunology. Published by Mosby, Inc. All rights reserved.

  13. Hearts and Minds: Real-Life Cardiotoxicity With Clozapine in Psychosis.

    Science.gov (United States)

    Joy, George; Whiskey, Eromona; Bolstridge, Mark; Porras-Segovia, Alejandro; McDonagh, Theresa A; Plymen, Carla M; Shergill, Sukhi S

    2017-12-01

    Schizophrenia has a 1% prevalence in the population; 30% of these patients are treatment refractory. Clozapine is the only drug licensed to treat treatment refractory psychosis, but concerns about potential adverse effects result in only a proportion of eligible patients being treated. Although a well-documented neutropenia risk is mitigated by routine blood testing, cardiac toxicity is a commonly cited reason to discontinue clozapine treatment. However, there is little data on the real-life cardiac outcomes in those receiving clozapine treatment. Retrospective review of electrocardiogram, echocardiogram, and clinical outcomes in 39 inpatients with treatment-refractory schizophrenia, treated with clozapine and other antipsychotic medication, referred for cardiology opinion. Commonest reasons for referral were development of left ventricular (LV) impairment or sinus tachycardia with normal LV function. Patients were reviewed by a range of cardiologists, receiving varied interventions.Median LV ejection fraction in the clozapine group was normal (52%). Serial echocardiograms demonstrated that clozapine-treated patients with LV impairment had no change in LV ejection fraction over a 4-month follow-up. Left ventricular ejection fraction did not differ between patients treated with clozapine and other antipsychotics. However, over an 11-year follow-up period, 48% of patients had discontinued clozapine treatment. This naturalistic study demonstrates that clozapine is not associated with significant cardiac mortality or morbidity. There is a real need for multidisciplinary working between specialist cardiologists and psychiatrists caring for these complex patients to facilitate optimal long-term physical and mental health outcomes.

  14. The impact of real life treatment strategies for Candida peritonitis-A retrospective analysis.

    Science.gov (United States)

    Dubler, S; Laun, M; Koch, C; Hecker, A; Weiterer, S; Siegler, B H; Röhrig, R; Weigand, M A; Lichtenstern, C

    2017-07-01

    Candida species are commonly detected isolates from abdominal foci. The question remains as to who would benefit from early empiric treatment in cases of Candida peritonitis. This study collected real-life data on critically ill patients with Candida peritonitis to estimate the relevance of the chosen treatment strategy on the outcome of these patients. One hundred and thirty-seven surgical intensive care unit (ICU) patients with intra-abdominal invasive Candidiasis were included in the study. Fifty-six patients did not get any antifungal agent. Twenty-nine patients were empirically treated, and 52 patients were specifically treated. In the group without, with empiric and with specific antifungal treatment, the 30-day mortality rate was 33.9, 48.3 and 44.2 respectively. Candida albicans was the most frequently found species. Seven patients in the specific treatment group and one patient in the empiric treatment group emerged with candidaemia. Age, leucocyte count, APACHE II Score and acute liver failure were independent predictors of 30-day mortality in patients with Candida peritonitis. Not all patients with Candida peritonitis received antifungal treatment in real clinical practice. Patients with higher morbidity more often got antifungals. Early empirical therapy has not been associated with a better 30-day mortality. © 2017 Blackwell Verlag GmbH.

  15. Issues of Application of Machine Learning Models for Virtual and Real-Life Buildings

    Directory of Open Access Journals (Sweden)

    Young Min Kim

    2016-06-01

    Full Text Available The current Building Energy Performance Simulation (BEPS tools are based on first principles. For the correct use of BEPS tools, simulationists should have an in-depth understanding of building physics, numerical methods, control logics of building systems, etc. However, it takes significant time and effort to develop a first principles-based simulation model for existing buildings—mainly due to the laborious process of data gathering, uncertain inputs, model calibration, etc. Rather than resorting to an expert’s effort, a data-driven approach (so-called “inverse” approach has received growing attention for the simulation of existing buildings. This paper reports a cross-comparison of three popular machine learning models (Artificial Neural Network (ANN, Support Vector Machine (SVM, and Gaussian Process (GP for predicting a chiller’s energy consumption in a virtual and a real-life building. The predictions based on the three models are sufficiently accurate compared to the virtual and real measurements. This paper addresses the following issues for the successful development of machine learning models: reproducibility, selection of inputs, training period, outlying data obtained from the building energy management system (BEMS, and validation of the models. From the result of this comparative study, it was found that SVM has a disadvantage in computation time compared to ANN and GP. GP is the most sensitive to a training period among the three models.

  16. FPGA-based real-time embedded system for RISS/GPS integrated navigation.

    Science.gov (United States)

    Abdelfatah, Walid Farid; Georgy, Jacques; Iqbal, Umar; Noureldin, Aboelmagd

    2012-01-01

    Navigation algorithms integrating measurements from multi-sensor systems overcome the problems that arise from using GPS navigation systems in standalone mode. Algorithms which integrate the data from 2D low-cost reduced inertial sensor system (RISS), consisting of a gyroscope and an odometer or wheel encoders, along with a GPS receiver via a Kalman filter has proved to be worthy in providing a consistent and more reliable navigation solution compared to standalone GPS receivers. It has been also shown to be beneficial, especially in GPS-denied environments such as urban canyons and tunnels. The main objective of this paper is to narrow the idea-to-implementation gap that follows the algorithm development by realizing a low-cost real-time embedded navigation system capable of computing the data-fused positioning solution. The role of the developed system is to synchronize the measurements from the three sensors, relative to the pulse per second signal generated from the GPS, after which the navigation algorithm is applied to the synchronized measurements to compute the navigation solution in real-time. Employing a customizable soft-core processor on an FPGA in the kernel of the navigation system, provided the flexibility for communicating with the various sensors and the computation capability required by the Kalman filter integration algorithm.

  17. Real remote physics experiments across Internet-- inherent part of Integrated e-Learning

    Directory of Open Access Journals (Sweden)

    Frantisek Lustig

    2008-05-01

    Full Text Available Abstract— The implementation of the real remote experiments across the Internet into teaching process, up till now not available, enables introduction of Integrated e-Learning, composed of three components: the real remote experiments across the Internet, the simulation applets and the electronic interactive textbooks. We present here the prospective remote laboratory system with data transfer using Intelligent School Experimental System (ISES as hardware and ISES WEB Control kit as software. This approach enables the simple construction of remote experiments without building any hardware and virtually no programming, only with paste and copy approach of pre-built typical blocks as camera view, controls, graphs, displays etc. In conclusion we summarize the achieved experience with remote experiments.

  18. EDITORIAL Wireless sensor networks: design for real-life deployment and deployment experiences Wireless sensor networks: design for real-life deployment and deployment experiences

    Science.gov (United States)

    Gaura, Elena; Roedig, Utz; Brusey, James

    2010-12-01

    modalities and (iv) system solutions with high end-user added value and cost benefits. The common thread is deployment and deployment evaluation. In particular, satisfaction of application requirements, involvement of the end-user in the design and deployment process, satisfactory system performance and user acceptance are concerns addressed in many of the contributions. The contributions form a valuable set, which help to identify the priorities for research in this burgeoning area: Robust, reliable and efficient data collection in embedded wireless multi-hop networks are essential elements in creating a true deploy-and-forget user experience. Maintaining full connectivity within a WSN, in a real world environment populated by other WSNs, WiFi networks or Bluetooth devices that constitute sources of interference is a key element in any application, but more so for those that are safety-critical, such as disaster response. Awareness of the effects of wireless channel, physical position and line-of-sight on received signal strength in real-world, outdoor environments will shape the design of many outdoor applications. Thus, the quantification of such effects is valuable knowledge for designers. Sensors' failure detection, scalability and commercialization are common challenges in many long-term monitoring applications; transferable solutions are evidenced here in the context of pollutant detection and water quality. Innovative, alternative thinking is often needed to achieve the desired long-lived networks when power-hungry sensors are foreseen components; in some instances, the very problems of wireless technology, such as RF irregularity, can be transformed into advantages. The importance of an iterative design and evaluation methodology—from analysis to simulation to real-life deployment—should be well understood by all WSN developers. The value of this is highlighted in the context of a challenging WPAN video-surveillance application based on a novel Nomadic Access

  19. The real limits to marine life: a further critique of the Respiration Index

    Science.gov (United States)

    Seibel, B. A.; Childress, J. J.

    2013-05-01

    The recently proposed "Respiration Index" (RI = log PO2/PCO2) suggests that aerobic metabolism is limited by the ratio of reactants (oxygen) to products (carbon dioxide) according to the thermodynamics of cellular respiration. Here, we demonstrate further that, because of the large standard free energy change for organic carbon oxidation (ΔG° = -686 kcal mol-1), carbon dioxide can never reach concentrations that would limit the thermodynamics of this reaction. A PCO2 to PO2 ratio of 10503 would be required to reach equilibrium (equilibrium constant, Keq = 10503), where ΔG = 0. Thus, a Respiration Index of -503 would be the real thermodynamic limit to aerobic life. Such a Respiration Index is never reached, either in the cell or in the environment. Moreover, cellular respiration and oxygen provision are kinetically controlled such that, within limits, environmental oxygen and CO2 concentrations have little to do with intracellular concentrations. The RI is fundamentally different from the aragonite saturation state, a thermodynamic index used to quantify the potential effect of CO2 on calcification rates, because of its failure to incorporate the equilibrium constant of the reaction. Not only is the RI invalid, but its use leads to incorrect and misleading predictions of the threat of changing oxygen and carbon dioxide to marine life. We provide a physiological framework that identifies oxygen thresholds and allows for synergistic effects of ocean acidification and global warming.

  20. The real limits to marine life: a further critique of the Respiration Index

    Directory of Open Access Journals (Sweden)

    B. A. Seibel

    2013-05-01

    Full Text Available The recently proposed "Respiration Index" (RI = log PO2/PCO2 suggests that aerobic metabolism is limited by the ratio of reactants (oxygen to products (carbon dioxide according to the thermodynamics of cellular respiration. Here, we demonstrate further that, because of the large standard free energy change for organic carbon oxidation (ΔG° = −686 kcal mol−1, carbon dioxide can never reach concentrations that would limit the thermodynamics of this reaction. A PCO2 to PO2 ratio of 10503 would be required to reach equilibrium (equilibrium constant, Keq = 10503, where ΔG = 0. Thus, a Respiration Index of −503 would be the real thermodynamic limit to aerobic life. Such a Respiration Index is never reached, either in the cell or in the environment. Moreover, cellular respiration and oxygen provision are kinetically controlled such that, within limits, environmental oxygen and CO2 concentrations have little to do with intracellular concentrations. The RI is fundamentally different from the aragonite saturation state, a thermodynamic index used to quantify the potential effect of CO2 on calcification rates, because of its failure to incorporate the equilibrium constant of the reaction. Not only is the RI invalid, but its use leads to incorrect and misleading predictions of the threat of changing oxygen and carbon dioxide to marine life. We provide a physiological framework that identifies oxygen thresholds and allows for synergistic effects of ocean acidification and global warming.

  1. Real-time functional integral approach to the quantum disordered spin systems

    International Nuclear Information System (INIS)

    Kopec, T.K.

    1989-01-01

    In this paper the effect of randomness and frustration in the quantum Ising spin glass in a transverse field is studied by using the thermofield dynamics (TFD), the real time, finite temperature quantum field theory. It is shown that the method can be conveniently used for the averaging of the free energy of the system by completely avoiding the use of the n-replica trick. The effective dynamic Lagrangian for the disorder averaged causal, correlations and response Green functions is derived by functional integral approach. Furthermore, the properties of this Lagrangian are analyzed by the saddle point method which leads to the self-consistent equation for the spin glass order parameter

  2. Fully integrated monolithic opoelectronic transducer for real.time protein and DNA detection

    DEFF Research Database (Denmark)

    Misiakos, Konstatinos; S. Petrou, Panagiota; E. Kakabakos, Sotirios

    2010-01-01

    The development and testing of a portable bioanalytical device which was capable for real-time monitoring of binding assays was demonstrated. The device was based on arrays of nine optoelectronic transducers monolithically integrated on silicon chips. The optocouplers consisted of nine silicon av...... by exploiting wavelength filtering on photonic crystal engineered waveguides. The proposed miniaturized sensing device with proper packaging and accompanied by a portable instrument can find wide application as a platform for reliable and cost effective point-of-care diagnosis....

  3. Real-Time Monitoring and Control of HgCdTe MBE Using an Integrated Multi-Sensor System

    National Research Council Canada - National Science Library

    Olson, G

    1998-01-01

    We present recent progress on the use of an integrated real-time sensing and control system for monitoring and controlling substrate temperature, layer composition, and effusion cell flux during MBE...

  4. Mutual Information Based Dynamic Integration of Multiple Feature Streams for Robust Real-Time LVCSR

    Science.gov (United States)

    Sato, Shoei; Kobayashi, Akio; Onoe, Kazuo; Homma, Shinichi; Imai, Toru; Takagi, Tohru; Kobayashi, Tetsunori

    We present a novel method of integrating the likelihoods of multiple feature streams, representing different acoustic aspects, for robust speech recognition. The integration algorithm dynamically calculates a frame-wise stream weight so that a higher weight is given to a stream that is robust to a variety of noisy environments or speaking styles. Such a robust stream is expected to show discriminative ability. A conventional method proposed for the recognition of spoken digits calculates the weights front the entropy of the whole set of HMM states. This paper extends the dynamic weighting to a real-time large-vocabulary continuous speech recognition (LVCSR) system. The proposed weight is calculated in real-time from mutual information between an input stream and active HMM states in a searchs pace without an additional likelihood calculation. Furthermore, the mutual information takes the width of the search space into account by calculating the marginal entropy from the number of active states. In this paper, we integrate three features that are extracted through auditory filters by taking into account the human auditory system's ability to extract amplitude and frequency modulations. Due to this, features representing energy, amplitude drift, and resonant frequency drifts, are integrated. These features are expected to provide complementary clues for speech recognition. Speech recognition experiments on field reports and spontaneous commentary from Japanese broadcast news showed that the proposed method reduced error words by 9.2% in field reports and 4.7% in spontaneous commentaries relative to the best result obtained from a single stream.

  5. Real-life effectiveness of smoking-cessation treatments in general practice clinics in Denmark. The Escape Smoke project

    DEFF Research Database (Denmark)

    Poulsen, Peter Bo; Spillemose, Heidi; Nielsen, Gerda

    2015-01-01

    BACKGROUND: The smoking prevalence has not decreased in the last years in Denmark. General practice (GP) offers smoking cessation (SC) treatment. Studies of real-life effectiveness of daily practice SC-activities from the GP-setting opposed to efficacy results from randomized clinical trials...... are few. The study aim was to evaluate the real-life effectiveness of SC-treatments for daily smokers among Danish GP-clinics. METHODS: In a multi-centre-based observational study design Danish GP-clinics with prior SC-activity recruited daily smokers motivated for quitting. As per usual clinical practice...

  6. Learning motivational interviewing in a real-life setting: a randomised controlled trial in the Swedish Prison Service.

    Science.gov (United States)

    Forsberg, Lars; Ernst, Denise; Farbring, Carl Åke

    2011-07-01

    Motivational interviewing (MI) is a client-centred, directive counselling style for helping people to explore and resolve ambivalence about behaviour change and shown to decrease drug and alcohol use. A five-session semi-structured MI intervention [Beteende, Samtal, Förändring (BSF; Behaviour, Counselling, Change)] was implemented in Swedish prisons. To examine whether, in a real-life implementation of semi-structured MI, staff receiving ongoing MI training, based on audio-recorded feedback in peer groups (BSF+), possess greater MI skill compared with staff receiving workshop-only MI training (BSF), and staff conducting usual prison planning interviews (UPI). Prisoners were randomised to one of the three interventions. The fi rst sessions between staff and prisoner with complete data were assessed with the Motivational Interviewing Treatment Integrity Code 3.0. Content analysis of 45 staff: prisoner sessions revealed that counsellors in the BSF+ group were significantly more competent in MI than those in the UPI group, but there was no difference in MI competency between the BSF and UPI groups. Overall, staff were rated as not having achieved beginning proficiency. Our findings suggest that staff delivering motivational interviewing programmes for substance-misusing prisoners in Sweden are not being given sufficient training for the task. Previous literature has suggested that staff need more than a basic 3- to 5-day workshop training, but our findings suggest that they may need longer-term continuing supervision and support than previously recognised.

  7. A commercial real-time manufacturing integration platform for the new control system on FTU

    International Nuclear Information System (INIS)

    Panella, M.; Bertocchi, A.; Bozzolan, V.; Buceti, G.; Centioli, C.; Imparato, A.; Mazza, G.; Torelli, C.; Vitale, V.

    1999-01-01

    In 1994 a working group was set up in Frascati to investigate how to build up a new control system for FTU (Frascati tokamak upgrade) considering the evolution in the information technology. Strong emphasis was placed on the use of standard solutions (be they de-facto or de-jure) and commercial platforms where-ever possible. This paper describes our operational experience with the new control system based on the commercial DEC BASEstar family of products. BASEstar is based on client/server computing technologies, providing an environment to collect, process, manage, distribute and integrate real time manufacturing data. UNIX, VMS, PC Win, OS-9 are integrated to handle hosts, PC, VME CPUs. A 4 GL programming language, CIMfast, has been used to handle via automatic procedures the tokamak discharge. X11 standard based mimics are available to display the plants status. A real flexibility of the whole system has been experience and the further use of the this system has been planned for the ITER DTP (divertor test platform). (orig.)

  8. Process mining routinely collected electronic health records to define real-life clinical pathways during chemotherapy.

    Science.gov (United States)

    Baker, Karl; Dunwoodie, Elaine; Jones, Richard G; Newsham, Alex; Johnson, Owen; Price, Christopher P; Wolstenholme, Jane; Leal, Jose; McGinley, Patrick; Twelves, Chris; Hall, Geoff

    2017-07-01

    There is growing interest in the use of routinely collected electronic health records to enhance service delivery and facilitate clinical research. It should be possible to detect and measure patterns of care and use the data to monitor improvements but there are methodological and data quality challenges. Driven by the desire to model the impact of a patient self-test blood count monitoring service in patients on chemotherapy, we aimed to (i) establish reproducible methods of process-mining electronic health records, (ii) use the outputs derived to define and quantify patient pathways during chemotherapy, and (iii) to gather robust data which is structured to be able to inform a cost-effectiveness decision model of home monitoring of neutropenic status during chemotherapy. Electronic Health Records at a UK oncology centre were included if they had (i) a diagnosis of metastatic breast cancer and received adjuvant epirubicin and cyclosphosphamide chemotherapy or (ii) colorectal cancer and received palliative oxaliplatin and infusional 5-fluorouracil chemotherapy, and (iii) were first diagnosed with cancer between January 2004 and February 2013. Software and a Markov model were developed, producing a schematic of patient pathways during chemotherapy. Significant variance from the assumed care pathway was evident from the data. Of the 535 patients with breast cancer and 420 with colorectal cancer there were 474 and 329 pathway variants respectively. Only 27 (5%) and 26 (6%) completed the planned six cycles of chemotherapy without having unplanned hospital contact. Over the six cycles, 169 (31.6%) patients with breast cancer and 190 (45.2%) patients with colorectal cancer were admitted to hospital. The pathways of patients on chemotherapy are complex. An iterative approach to addressing semantic and data quality issues enabled the effective use of routinely collected patient records to produce accurate models of the real-life experiences of chemotherapy patients and

  9. Tool life and surface integrity aspects when drilling nickel alloy

    Science.gov (United States)

    Kannan, S.; Pervaiz, S.; Vincent, S.; Karthikeyan, R.

    2018-04-01

    Nickel based super alloys manufactured through powder metallurgy (PM) route are required to increase the operational efficiency of gas turbine engines. They are material of choice for high pressure components due to their superior high temperature strength, excellent corrosion, oxidation and creep resistance. This unique combination of mechanical and thermal properties makes them even more difficult-to-machine. In this paper, the hole making process using coated carbide inserts by drilling and plunge milling for a nickel-based powder metallurgy super alloy has been investigated. Tool life and process capability studies were conducted using optimized process parameters using high pressure coolants. The experimental trials were directed towards an assessment of the tendency for surface malformations and detrimental residual stress profiles. Residual stresses in both the radial and circumferential directions have been evaluated as a function of depth from the machined surface using the target strain gauge / center hole drilling method. Circumferential stresses near workpiece surface and at depth of 512 µm in the starting material was primarily circumferential compression which was measured to be average of –404 MPa. However, the radial stresses near workpiece surface was tensile and transformed to be compressive in nature at depth of 512 µm in the starting material (average: -87 Mpa). The magnitude and the depth below the machined surface in both radial and circumferential directions were primarily tensile in nature which increased with hole number due to a rise of temperature at the tool–workpiece interface with increasing tool wear. These profiles are of critical importance for the selection of cutting strategies to ensure avoidance/minimization of tensile residual stresses that can be detrimental to the fatigue performance of the components. These results clearly show a tendency for the circumferential stresses to be more tensile than the radial stresses

  10. A Proficiency Based Stepwise Endovascular Curricular Training (PROSPECT) Program Enhances Operative Performance in Real Life: A Randomised Controlled Trial.

    Science.gov (United States)

    Maertens, H; Aggarwal, R; Moreels, N; Vermassen, F; Van Herzeele, I

    2017-09-01

    Healthcare evolution requires optimisation of surgical training to provide safe patient care. Operating room performance after completion of proficiency based training in vascular surgery has not been investigated. A randomised controlled trial evaluated the impact of a Proficiency based Stepwise Endovascular Curricular Training program (PROSPECT) on the acquisition of endovascular skills and the transferability of these skills to real life interventions. All subjects performed two endovascular interventions treating patients with symptomatic iliac and/or superficial femoral artery stenosis under supervision. Primary outcomes were technical performances (Global Rating Scale [GRS]; Examiner Checklist), operative metrics, and patient outcomes, adjusted for case difficulty and trainee experience. Secondary outcomes included knowledge and technical performance after 6 weeks and 3 months. Thirty-two general surgical trainees were randomised into three groups. Besides traditional training, the first group (n = 11) received e-learning and simulation training (PROSPECT), the second group (n = 10) only had access to e-learning, while controls (n = 11) did not receive supplementary training. Twenty-nine trainees (3 dropouts) performed 58 procedures. Trainees who completed PROSPECT showed superior technical performance (GRS 39.36 ± 2.05; Checklist 63.51 ± 3.18) in real life with significantly fewer supervisor takeovers compared with trainees receiving e-learning alone (GRS 28.42 ± 2.15; p = .001; Checklist 53.63 ± 3.34; p = .027) or traditional education (GRS 23.09 ± 2.18; p = .001; Checklist 38.72 ± 3.38; p = .001). Supervisors felt more confident in allowing PROSPECT trained physicians to perform basic (p = .006) and complex (p = .003) procedures. No differences were detected in procedural parameters (such as fluoroscopy time, DAP, procedure time, etc.) or complications. Proficiency levels were maintained up to 3 months. A structured

  11. Real-life memory and spatial navigation in patients with focal epilepsy: ecological validity of a virtual reality supermarket task.

    Science.gov (United States)

    Grewe, P; Lahr, D; Kohsik, A; Dyck, E; Markowitsch, H J; Bien, C G; Botsch, M; Piefke, M

    2014-02-01

    Ecological assessment and training of real-life cognitive functions such as visual-spatial abilities in patients with epilepsy remain challenging. Some studies have applied virtual reality (VR) paradigms, but external validity of VR programs has not sufficiently been proven. Patients with focal epilepsy (EG, n=14) accomplished an 8-day program in a VR supermarket, which consisted of learning and buying items on a shopping list. Performance of the EG was compared with that of healthy controls (HCG, n=19). A comprehensive neuropsychological examination was administered. Real-life performance was investigated in a real supermarket. Learning in the VR supermarket was significantly impaired in the EG on different VR measures. Delayed free recall of products did not differ between the EG and the HCG. Virtual reality scores were correlated with neuropsychological measures of visual-spatial cognition, subjective estimates of memory, and performance in the real supermarket. The data indicate that our VR approach allows for the assessment of real-life visual-spatial memory and cognition in patients with focal epilepsy. The multimodal, active, and complex VR paradigm may particularly enhance visual-spatial cognitive resources. Copyright © 2013 Elsevier Inc. All rights reserved.

  12. An integrated life cycle inventory for demolition processes in the context of life cycle sustainability assessment

    DEFF Research Database (Denmark)

    Bozhilova-Kisheva, Kossara Petrova; Hu, Mingming; van Roekel, Eric

    2012-01-01

    According to the Life Cycle Assessment in Building and Construction: State-of-the-Art Report (2003), the dismantling and demolition stage of the building life cycle is only sometimes included in the Life Cycle Inventory (LCI) when doing Life Cycle Assessments (LCA). The reason that it is less...... inventoried in a traditional LCA maybe because this stage is expected to have a negligible environmental impact comparing to other stages in the life cycle of the buildings. When doing a life cycle sustainability assessment considering not only environmental but also economic and social impacts, the impacts...

  13. Real time capable control design with increased life expectancy for research purposes

    Science.gov (United States)

    Epple, S.; Jung, R.; Jalba, K.; Nasui, V.

    2017-05-01

    A new, freely programmable, scalable control system for academic research purposes was developed. The intention was, to have a control unit capable of handling multiple PT1000 temperature sensors at reasonable accuracy and temperature range, as well as digital input signals and providing more powerful output signals at 230V AC than conventional control units. To take full advantage of the system, control-loops are run in real time. The whole system runs independently of a personal computer. The two on-board RS232 connectors allow to connect further units to use more sensors or actuators or to connect other laboratory equipment, as required. To allow usage for long-time experiments, systematically electronic components with low failure-in-time (FIT) rate have been chosen in order to achieve high life expectancy. This paper describes the third prototype, which now provides stable measurements, and an improvement in accuracy compared to the previous designs. A rough estimation about the expected mean time between failures is given. As test case, a thermal solar system to produce hot tap water and assist heating in a single-family house was implemented. The solar fluid pump was power-controlled and several temperatures at different points in the hydraulic system were measured and used in the control algorithms. The hardware design proved suitable to test several different control strategies and their corresponding algorithms for the thermal solar system.

  14. A real-time PCR approach to detect predation on anchovy and sardine early life stages

    Science.gov (United States)

    Cuende, Elsa; Mendibil, Iñaki; Bachiller, Eneko; Álvarez, Paula; Cotano, Unai; Rodriguez-Ezpeleta, Naiara

    2017-12-01

    Recruitment of sardine (Sardina pilchardus Walbaum, 1792) and anchovy (Engraulis encrasicolus Linnaeus, 1758) is thought to be regulated by predation of their eggs and larvae. Predators of sardine and anchovy can be identified by visual taxonomic identification of stomach contents, but this method is time consuming, tedious and may underestimate predation, especially in small predators such as fish larvae. Alternatively, genetic tools may offer a more cost-effective and accurate alternative. Here, we have developed a multiplex real-time polymerase chain reaction (RT-PCR) assay based on TaqMan probes to simultaneously detect sardine and anchovy remains in gut contents of potential predators. The assay combines previously described and newly generated species-specific primers and probes for anchovy and sardine detection respectively, and allows the detection of 0,001 ng of target DNA (which corresponds to about one hundredth of the total DNA present in a single egg). We applied the method to candidate anchovy and sardine egg predators in the Bay of Biscay, Atlantic Mackerel (Scomber scombrus) larvae. Egg predation observed was limited primarily to those stations where sardine and/or anchovy eggs were present. Our developed assay offers a suitable tool to understand the effects of predation on the survival of anchovy and sardine early life stages.

  15. Regorafenib in the Real-Life Clinical Practice: Data from the Czech Registry.

    Science.gov (United States)

    Kopeckova, Katerina; Buchler, Tomas; Bortlicek, Zbynek; Hejduk, Karel; Chloupkova, Renata; Melichar, Bohuslav; Pokorna, Petra; Tomasek, Jiri; Linke, Zdenek; Petruzelka, Lubos; Kiss, Igor; Prausova, Jana

    2017-02-01

    To describe the use of regorafenib for the treatment of metastatic colorectal cancer (mCRC) in clinical practice in the Czech Republic, and to describe the clinical outcomes of patients in terms of safety and survival. The data of patients treated with regorafenib were extracted from the national CORECT registry. The CORECT registry is a non-interventional post-marketing database, gathering information about patients with CRC and treated with targeted agents. Twenty oncology centres in the Czech Republic contributed to this registry. Collected data included patients' characteristics, disease history, cancer treatments, response to treatments and safety. A total of 148 patients treated with regorafenib in clinical practice were analysed. At regorafenib initiation, almost all patients were fully active or slightly restricted in physical activity. Regorafenib was not administered as first-line treatment in any patient. Median progression-free survival was 3.5 months and median overall survival was 9.3 months. One-year survival rate was 44.6 %. Four partial responses were observed and 51 stable diseases. Progression was observed in 66 patients (44.6 %). The main reported adverse events were skin toxicity (5.4 %) and fatigue (2.0 %). Regorafenib is a well-established treatment for pretreated patients with mCRC, however real-life data are scarce. Our results demonstrated slightly better efficacy of regorafenib and better safety profile in patients with mCRC compared to the randomised trials.

  16. A real life clinical practice of neurologists in the ambulatory setting in Thailand: a pragmatic study

    Directory of Open Access Journals (Sweden)

    Kannikar Kongbunkiat

    2015-06-01

    Full Text Available The burden of neurological disorders is high in developing countries. Real life data from neurologists as to how they practice in Thailand are limited in literature. Practices of neurologists in a university hospital clinical setting in Thailand were studied. A prospective study was performed at the ambulatory neurology clinic, Khon Kaen University Hospital, between 1 February and 31 October 2009. The following data were recorded: numbers of patients, characteristics of patients, consultation notes, and time spent for each patient. There were three neurologists, each of whom ran one afternoon clinic, once a week. There were 6137 visits during the 9 months, with an average of 681 visits per month. The total number of patients was 2834. The three most common diseases were cerebrovascular diseases (33%, epilepsy (16%, and movement disorders (non-Parkinson’s disease, 12%. Neurologists spent an average of 6.34 minutes per patient. In conclusion, neurologists in medical schools have limited time to take care of each patient. Several strategies are needed in medical education and neurology training to improve the quality of care.

  17. Exploring sustainability transitions in households: insights from real-life experiments

    Science.gov (United States)

    Baedeker, Carolin; Buhl, Johannes; Greiff, Kathrin; Hasselkuß, Marco; Liedtke, Christa; Lukas, Melanie

    2016-04-01

    Societal transformation towards sustainable consumption and production, especially in urban areas, is a key challenge. The design and implementation of sustainable product service systems (PSS) might be the initial point, in which private households play a major role. The Sustainable LivingLab research infrastructure was developed as an experimental setting for investigating consumption and production patterns in private households, especially to explore socio-technical innovations which are helpful to guide sustainability transitions. The suggested presentation describes results of several real-life experiments conducted in German households, e.g. the project SusLabNRW (North-Rhine Westphalia as part of the European SusLabNWE-Project), the EnerTransRuhr project as well as the PATHWAYS project that explore patterns of action, time use, social practices and the related resource use in private households. The presentation gives an overview of the employed methods and analysed data (qualitative interviews, social network analysis, survey on household activities and inventories and a sustainability assessment (resource profiles - MIPS household analysis). Households' resource consumption was calculated in all fields of activity to analyse social practices' impact. The presentation illustrates how aggregated data can inform scenario analysis and concludes with an outlook onto transition pathways at household level and socio-technical innovations in the fields of housing, nutrition and mobility.

  18. Moving through time: the role of personality in three real-life contexts.

    Science.gov (United States)

    Duffy, Sarah E; Feist, Michele I; McCarthy, Steven

    2014-01-01

    In English, two deictic space-time metaphors are in common usage: the Moving Ego metaphor conceptualizes the ego as moving forward through time and the Moving Time metaphor conceptualizes time as moving forward toward the ego (Clark, 1973). Although earlier research investigating the psychological reality of these metaphors has typically examined spatial influences on temporal reasoning (e.g., Boroditsky & Ramscar, 2002), recent lines of research have extended beyond this, providing initial evidence that personality differences and emotional experiences may also influence how people reason about events in time (Duffy & Feist, 2014; Hauser, Carter, & Meier, 2009; Richmond, Wilson, & Zinken, 2012). In this article, we investigate whether these relationships have force in real life. Building on the effects of individual differences in self-reported conscientiousness and procrastination found by Duffy and Feist (2014), we examined whether, in addition to self-reported conscientiousness and procrastination, there is a relationship between conscientious and procrastinating behaviors and temporal perspective. We found that participants who adopted the Moving Time perspective were more likely to exhibit conscientious behaviors, while those who adopted the Moving Ego perspective were more likely to procrastinate, suggesting that the earlier effects reach beyond the laboratory. Copyright © 2014 Cognitive Science Society, Inc.

  19. Emotive hemispheric differences measured in real-life portraits using pupil diameter and subjective aesthetic preferences.

    Science.gov (United States)

    Blackburn, Kelsey; Schirillo, James

    2012-06-01

    The biased positioning of faces exposed to viewers of Western portraiture has suggested there may be fundamental differences in the lateralized expression and perception of emotion. The present study investigates whether there are differences in the perception of the left and right sides of the face in real-life photographs of individuals. The study paired conscious aesthetic ratings of pleasantness with measurements of pupil size, which are thought to be a reliable unconscious measure of interest first tested by Hess. Images of 10 men and 10 women were taken from the left and right sides of the face. These images were also mirror-reversed. As expected, we found a strong preference for left-sided portraits (regardless of original or mirror-reversed orientation), such that left hemifaces elicited higher ratings and greater pupil dilation. Interestingly, this effect was true of both sexes. A positive linear relationship was also found between pupil size and aesthetic ratings such that pupil size increased with pleasantness ratings. These findings provide support for the notions of lateralized emotion, right-hemispheric dominance, pupillary dilation to pleasant images, and constriction to unpleasant images.

  20. From All Walks of Life: New Hope for School Integration

    Science.gov (United States)

    Kahlenberg, Richard D.

    2013-01-01

    Integrating our schools is a goal that many of us share. But some seem to have given up on the idea, as plans to boost racial diversity have come under attack, and as the fixation on test scores has narrowed some people's concept of a good education. There is, however, new hope: integration by socioeconomic status. It's a cost-effective, legally…

  1. Pretreatment of Real Wastewater from the Chocolate Manufacturing Industry through an Integrated Process of Electrocoagulation and Sand Filtration

    Directory of Open Access Journals (Sweden)

    Marco A. García-Morales

    2018-01-01

    Full Text Available The purpose of this study was to evaluate the efficiency of removal of suspended solids in terms of turbidity, color, and chemical oxygen demand (COD when integrating the electrocoagulation process using aluminum sacrificial anodes and the sand filtration process as a pretreatment of wastewater from the chocolate manufacturing plant in Toluca, México. Wastewater from the chocolate manufacturing industry used in this study is classified as nontoxic, but is characterized as having a high content of color (5952 ± 76 Pt-Co, turbidity (1648 ± 49 FAU, and COD (3608 ± 250 mg/L. Therefore, enhanced performance could be achieved by combining pretreatment techniques to increase the efficiencies of the physical, chemical, and biological treatments. In the integrated process, there was a turbidity reduction of 96.1 ± 0.2% and an increase in dissolved oxygen from 3.8 ± 0.05 mg/L (inlet sand filtration to 6.05 ± 0.03 mg/L (outlet sand filtration after 120 min of treatment. These results indicate good water quality necessary for all forms of elemental life. Color and COD removals were 98.2 ± 0.2% and 39.02 ± 2.2%, respectively, during the electrocoagulation process (0.2915 mA/cm2 current density and 120 min of treatment. The proposed integrated process could be an attractive alternative of pretreatment of real wastewater to increase water quality of conventional treatments.

  2. The use of questionnaires in colour research in real-life settings : In search of validity and methodological pitfalls

    NARCIS (Netherlands)

    Bakker, I.C.; van der Voordt, Theo; Vink, P.; de Boon, J

    2014-01-01

    This research discusses the validity of applying questionnaires in colour research in real life settings.
    In the literature the conclusions concerning the influences of colours on human performance and well-being are often conflicting. This can be caused by the artificial setting of the test

  3. Menu-engineering in restaurants - adapting portion sizes on plates to enhance vegetable consumption: a real-life experiment.

    NARCIS (Netherlands)

    Reinders, M.J.; Huitink, M.; Dijkstra, S.C.; Maaskant, A.J.; Heijnen, J.

    2017-01-01

    Background: The aim of this research was to investigate whether increased portion sizes of vegetables and decreased portion sizes of meat on main dishes increased the amount of vegetables consumed in a real-life restaurant setting without affecting customer satisfaction. The participants were

  4. Mapping real-life applications on run-time reconfigurable NoC-based MPSoC on FPGA.

    NARCIS (Netherlands)

    Singh, A.K.; Kumar, A.; Srikanthan, Th.; Ha, Y.

    2010-01-01

    Multiprocessor systems-on-chip (MPSoC) are required to fulfill the performance demand of modern real-life embedded applications. These MPSoCs are employing Network-on-Chip (NoC) for reasons of efficiency and scalability. Additionally, these systems need to support run-time reconfiguration of their

  5. Exploring Marine Ecosystems with Elementary School Portuguese Children: Inquiry-Based Project Activities Focused on "Real-Life" Contexts

    Science.gov (United States)

    Guilherme, Elsa; Faria, Cláudia; Boaventura, Diana

    2016-01-01

    The purpose of the study was to investigate how young students engage in an inquiry-based project driven by real-life contexts. Elementary school children were engaged in a small inquiry project centred on marine biodiversity and species adaptations. All activities included the exploration of an out-of-school setting as a learning context. A total…

  6. The fragrance hand immersion study - an experimental model simulating real-life exposure for allergic contact dermatitis on the hands

    DEFF Research Database (Denmark)

    Heydorn, S; Menné, T; Andersen, K E

    2003-01-01

    .p.m.), whilst during the following 2 weeks, the concentration was relatively high (approximately 250 p.p.m.), imitating real-life exposure to a household product like dishwashing liquid diluted in water and the undiluted product, respectively. Evaluation was made using a clinical scale and laser Doppler flow...

  7. Blue Tigers, Black Tapirs, & the Pied Raven of the Faroe Islands: Teaching Genetic Drift Using Real-Life Animal Examples

    Science.gov (United States)

    Robischon, Marcel

    2015-01-01

    Genetic drift is a concept of population genetics that is central to understanding evolutionary processes and aspects of conservation biology. It is frequently taught using rather abstract representations. I introduce three real-life zoological examples, based on historical and recent color morphs of tigers, tapirs, and ravens, that can complement…

  8. Using Real-Worldness and Cultural Difference to Enhance Student Learning in a Foundation Phase Life Skills Module

    Science.gov (United States)

    Koen, Mariette; Ebrahim, Hasina Banu

    2013-01-01

    Our aim was to explore how real-world experience, inclusive of engagement with cultural differences, influences the quality of students' learning in a Life Skills module in pre-service Foundation Phase teacher education. The study was conducted with 147 students in their final year of the Bachelor of Education (Foundation Phase specialisation), at…

  9. Real-life efficacy and safety of omalizumab in Portuguese patients with persistent uncontrolled asthma.

    Science.gov (United States)

    Pereira Barbosa, M; Bugalho de Almeida, A; Pereira, C; Chen, C-W; Georgiou, P; Peachey, G

    2015-01-01

    The real life effectiveness, safety and the use of omalizumab for Portuguese patients with uncontrolled persistent allergic asthma are not sufficiently well known. The objective of this report was to make an evaluation, in a post-marketing, non-interventional, observational registry, of the Portuguese population included in the eXpeRience study. The methods used in this report are the same as the global eXpeRience ones, applied to a Portuguese sub-population. Patients with uncontrolled allergic asthma who had started omalizumab within the previous 15 weeks were enrolled and received omalizumab add-on therapy for 24 months. The physicians' global evaluation of treatment effectiveness (GETE), asthma symptoms and control (ACT score), quality of life (mini-AQLQ score), exacerbations, and serious adverse events (SAE) were reported. Of the 943 patients recruited in the eXpeRience registry, 62 patients were from Portugal. 62.1% of them were observed to be responders with good/excellent GETE assessment at Week 16. Clinically meaningful improvements in asthma control (ACT score) and quality of life (mini-AQLQ score) were observed with omalizumab therapy at Months 12 (mean change: +7.7 [n=35]; +2.1 [n=20], respectively) and 24 (mean change: +7.0 [n=26]; +2.7 [n=13], respectively). Asthma symptoms and rescue medication usage were reduced to ≤1 day/week at Month 24 from a baseline of ≥3.5 days/week. The proportion of patients with no clinically significant exacerbations increased from 6.5% during pre-treatment (n=62) to 50% at Month 12 (n=54) and 60% at Month 24 (n=45). The findings from the Portugal subpopulation of eXpeRience registry confirm that omalizumab add-on therapy is efficacious and well tolerated in the management of uncontrolled persistent allergic asthma. Another pertinent issue is the fact that the Portuguese subpopulation response is similar to the international population average of the study. Copyright © 2014 Sociedade Portuguesa de Pneumologia

  10. Exploring Subseafloor Life with the Integrated Ocean Drilling Program

    Directory of Open Access Journals (Sweden)

    Patricia Sobecky

    2007-09-01

    Full Text Available Deep drilling of marine sediments and igneous crust offers a unique opportunity to explore how life persists and evolves in the Earth’s deepest subsurface ecosystems. Resource availability deep beneath the seafloor may impose constraints on microbial growth and dispersal patterns that differ greatly from those in the surface world. Processes that mediate microbial evolution and diversity may also be very different in these habitats, which approach and probably passthe extreme limits of life. Communities in parts of the deep subsurface may resemble primordial microbial ecosystems, and may serve as analogues of life on other planetary bodies, such as Mars or Europa, that have or once had water.

  11. Adapting the SLIM diabetes prevention intervention to a Dutch real-life setting: joint decision making by science and practice.

    Science.gov (United States)

    Jansen, Sophia C; Haveman-Nies, Annemien; Duijzer, Geerke; Ter Beek, Josien; Hiddink, Gerrit J; Feskens, Edith J M

    2013-05-08

    Although many evidence-based diabetes prevention interventions exist, they are not easily applicable in real-life settings. Moreover, there is a lack of examples which describe the adaptation process of these interventions to practice. In this paper we present an example of such an adaptation. We adapted the SLIM (Study on Lifestyle intervention and Impaired glucose tolerance Maastricht) diabetes prevention intervention to a Dutch real-life setting, in a joint decision making process of intervention developers and local health care professionals. We used 3 adaptation steps in accordance with current adaptation frameworks. In the first step, the elements of the SLIM intervention were identified. In the second step, these elements were judged for their applicability in a real-life setting. In the third step, adaptations were proposed and discussed for those elements which were deemed not applicable. Participants invited for this process included intervention developers and local health care professionals (n=19). In the first adaptation step, a total of 22 intervention elements were identified. In the second step, 12 of these 22 intervention elements were judged as inapplicable. In the third step, a consensus was achieved for the adaptations of all 12 elements. The adapted elements were in the following categories: target population, techniques, intensity, delivery mode, materials, organisational structure, and political and financial conditions. The adaptations either lay in changing the SLIM protocol (6 elements) or the real-life working procedures (1 element), or a combination of both (4 elements). The positive result of this study is that a consensus was achieved within a relatively short time period (nine months) between the developers of the SLIM intervention and local health care professionals on the adaptations needed to make SLIM applicable in a Dutch real-life setting. Our example shows that it is possible to combine the perspectives of scientists and

  12. Standard integral table algebras generated by non-real element of small degree

    CERN Document Server

    Muzychuk, Mikhail

    2002-01-01

    This book is addressed to the researchers working in the theory of table algebras and association schemes. This area of algebraic combinatorics has been rapidly developed during the last decade. The volume contains further developments in the theory of table algebras. It collects several papers which deal with a classification problem for standard integral table algebras (SITA). More precisely, we consider SITA with a faithful non-real element of small degree. It turns out that such SITA with some extra conditions may be classified. This leads to new infinite series of SITA which has interesting properties. The last section of the book uses a part of obtained results in the classification of association schemes. This volume summarizes the research which was done at Bar-Ilan University in the academic year 1998/99.

  13. Integrating SAR with Optical and Thermal Remote Sensing for Operational Near Real-Time Volcano Monitoring

    Science.gov (United States)

    Meyer, F. J.; Webley, P.; Dehn, J.; Arko, S. A.; McAlpin, D. B.

    2013-12-01

    multiple observation geometries in change detection procedures. Additionally, it will be shown how SAR-based hazard information can be integrated with data from optical satellites, thermal sensors, webcams and models to create near-real time volcano hazard information. We will introduce a prototype monitoring system that integrates SAR-based hazard information into the near real-time volcano hazard monitoring system of the Alaska Volcano Observatory. This prototype system was applied to historic eruptions of the volcanoes Okmok and Augustine, both located in the North Pacific. We will show that for these historic eruptions, the addition of SAR data lead to a significant improvement in activity detection and eruption monitoring, and improved the accuracy and timeliness of eruption alerts.

  14. An integrated portable hand-held analyser for real-time isothermal nucleic acid amplification

    Energy Technology Data Exchange (ETDEWEB)

    Smith, Matthew C. [College of Marine Science, University of South Florida, St Petersburg, FL (United States)], E-mail: msmith@marine.usf.edu; Steimle, George; Ivanov, Stan; Holly, Mark; Fries, David P. [College of Marine Science, University of South Florida, St Petersburg, FL (United States)

    2007-08-29

    A compact hand-held heated fluorometric instrument for performing real-time isothermal nucleic acid amplification and detection is described. The optoelectronic instrument combines a Printed Circuit Board/Micro Electro Mechanical Systems (PCB/MEMS) reaction detection/chamber containing an integrated resistive heater with attached miniature LED light source and photo-detector and a disposable glass waveguide capillary to enable a mini-fluorometer. The fluorometer is fabricated and assembled in planar geometry, rolled into a tubular format and packaged with custom control electronics to form the hand-held reactor. Positive or negative results for each reaction are displayed to the user using an LED interface. Reaction data is stored in FLASH memory for retrieval via an in-built USB connection. Operating on one disposable 3 V lithium battery >12, 60 min reactions can be performed. Maximum dimensions of the system are 150 mm (h) x 48 mm (d) x 40 mm (w), the total instrument weight (with battery) is 140 g. The system produces comparable results to laboratory instrumentation when performing a real-time nucleic acid sequence-based amplification (NASBA) reaction, and also displayed comparable precision, accuracy and resolution to laboratory-based real-time nucleic acid amplification instrumentation. A good linear response (R{sup 2} = 0.948) to fluorescein gradients ranging from 0.5 to 10 {mu}M was also obtained from the instrument indicating that it may be utilized for other fluorometric assays. This instrument enables an inexpensive, compact approach to in-field genetic screening, providing results comparable to laboratory equipment with rapid user feedback as to the status of the reaction.

  15. An integrated portable hand-held analyser for real-time isothermal nucleic acid amplification

    International Nuclear Information System (INIS)

    Smith, Matthew C.; Steimle, George; Ivanov, Stan; Holly, Mark; Fries, David P.

    2007-01-01

    A compact hand-held heated fluorometric instrument for performing real-time isothermal nucleic acid amplification and detection is described. The optoelectronic instrument combines a Printed Circuit Board/Micro Electro Mechanical Systems (PCB/MEMS) reaction detection/chamber containing an integrated resistive heater with attached miniature LED light source and photo-detector and a disposable glass waveguide capillary to enable a mini-fluorometer. The fluorometer is fabricated and assembled in planar geometry, rolled into a tubular format and packaged with custom control electronics to form the hand-held reactor. Positive or negative results for each reaction are displayed to the user using an LED interface. Reaction data is stored in FLASH memory for retrieval via an in-built USB connection. Operating on one disposable 3 V lithium battery >12, 60 min reactions can be performed. Maximum dimensions of the system are 150 mm (h) x 48 mm (d) x 40 mm (w), the total instrument weight (with battery) is 140 g. The system produces comparable results to laboratory instrumentation when performing a real-time nucleic acid sequence-based amplification (NASBA) reaction, and also displayed comparable precision, accuracy and resolution to laboratory-based real-time nucleic acid amplification instrumentation. A good linear response (R 2 = 0.948) to fluorescein gradients ranging from 0.5 to 10 μM was also obtained from the instrument indicating that it may be utilized for other fluorometric assays. This instrument enables an inexpensive, compact approach to in-field genetic screening, providing results comparable to laboratory equipment with rapid user feedback as to the status of the reaction

  16. Real time hardware implementation of power converters for grid integration of distributed generation and STATCOM systems

    Science.gov (United States)

    Jaithwa, Ishan

    Deployment of smart grid technologies is accelerating. Smart grid enables bidirectional flows of energy and energy-related communications. The future electricity grid will look very different from today's power system. Large variable renewable energy sources will provide a greater portion of electricity, small DERs and energy storage systems will become more common, and utilities will operate many different kinds of energy efficiency. All of these changes will add complexity to the grid and require operators to be able to respond to fast dynamic changes to maintain system stability and security. This thesis investigates advanced control technology for grid integration of renewable energy sources and STATCOM systems by verifying them on real time hardware experiments using two different systems: d SPACE and OPAL RT. Three controls: conventional, direct vector control and the intelligent Neural network control were first simulated using Matlab to check the stability and safety of the system and were then implemented on real time hardware using the d SPACE and OPAL RT systems. The thesis then shows how dynamic-programming (DP) methods employed to train the neural networks are better than any other controllers where, an optimal control strategy is developed to ensure effective power delivery and to improve system stability. Through real time hardware implementation it is proved that the neural vector control approach produces the fastest response time, low overshoot, and, the best performance compared to the conventional standard vector control method and DCC vector control technique. Finally the entrepreneurial approach taken to drive the technologies from the lab to market via ORANGE ELECTRIC is discussed in brief.

  17. Alpha: A real-time decentralized operating system for mission-oriented system integration and operation

    Science.gov (United States)

    Jensen, E. Douglas

    1988-01-01

    Alpha is a new kind of operating system that is unique in two highly significant ways. First, it is decentralized transparently providing reliable resource management across physically dispersed nodes, so that distributed applications programming can be done largely as though it were centralized. And second, it provides comprehensive, high technology support for real-time system integration and operation, an application area which consists predominately of aperiodic activities having critical time constraints such as deadlines. Alpha is extremely adaptable so that it can be easily optimized for a wide range of problem-specific functionality, performance, and cost. Alpha is the first systems effort of the Archons Project, and the prototype was created at Carnegie-Mellon University directly on modified Sun multiprocessor workstation hardware. It has been demonstrated with a real-time C(sup 2) application. Continuing research is leading to a series of enhanced follow-ons to Alpha; these are portable but initially hosted on Concurrent's MASSCOMP line of multiprocessor products.

  18. Real Time Integration of Field Data Into a GIS Platform for the Management of Hydrological Emergencies

    Science.gov (United States)

    Mangiameli, M.; Mussumeci, G.

    2013-01-01

    A wide series of events requires immediate availability of information and field data to be provided to decision-makers. An example is the necessity of quickly transferring the information acquired from monitoring and alerting sensors or the data of the reconnaissance of damage after a disastrous event to an Emergency Operations Center. To this purpose, we developed an integrated GIS and WebGIS system to dynamically create and populate via Web a database with spatial features. In particular, this work concerns the gathering and transmission of spatial data and related information to the desktop GIS so that they can be displayed and analyzed in real time to characterize the operational scenario and to decide the rescue interventions. As basic software, we used only free and open source: QuantumGIS and Grass as Desktop GIS, Map Server with PMapper application for the Web-Gis functionality and PostGreSQL/PostGIS as Data Base Management System (DBMS). The approach has been designed, developed and successfully tested in the management of GIS-based navigation of an autonomous robot, both to map its trajectories and to assign optimal paths. This paper presents the application of our system to a simulated hydrological event that could interest the province of Catania, in Sicily. In particular, assuming that more teams draw up an inventory of the damage, we highlight the benefits of real-time transmission of the information collected from the field to headquarters.

  19. REAL TIME INTEGRATION OF FIELD DATA INTO A GIS PLATFORM FOR THE MANAGEMENT OF HYDROLOGICAL EMERGENCIES

    Directory of Open Access Journals (Sweden)

    M. Mangiameli

    2014-01-01

    Full Text Available A wide series of events requires immediate availability of information and field data to be provided to decision-makers. An example is the necessity of quickly transferring the information acquired from monitoring and alerting sensors or the data of the reconnaissance of damage after a disastrous event to an Emergency Operations Center. To this purpose, we developed an integrated GIS and WebGIS system to dynamically create and populate via Web a database with spatial features. In particular, this work concerns the gathering and transmission of spatial data and related information to the desktop GIS so that they can be displayed and analyzed in real time to characterize the operational scenario and to decide the rescue interventions. As basic software, we used only free and open source: QuantumGIS and Grass as Desktop GIS, Map Server with PMapper application for the Web-Gis functionality and PostGreSQL/PostGIS as Data Base Management System (DBMS. The approach has been designed, developed and successfully tested in the management of GIS-based navigation of an autonomous robot, both to map its trajectories and to assign optimal paths. This paper presents the application of our system to a simulated hydrological event that could interest the province of Catania, in Sicily. In particular, assuming that more teams draw up an inventory of the damage, we highlight the benefits of real-time transmission of the information collected from the field to headquarters.

  20. RODOS and RESY: two integrated real time on-line decision support systems for nuclear emergencies

    International Nuclear Information System (INIS)

    Ehrhardt, J.; Fischer, F.; Paesler-Sauer, J.; Schuele, O.; Benz, G.; Rafat, M.

    1993-01-01

    Based on the experience gained with the development of the German real-time system RESY for near range and early phase decision support KfK has developed the hardware and software framework of RODOS, the EC real-time on-line decision support system for nuclear emergencies. The first prototype version of RODOS incorporates models for atmospheric dispersion, for external and internal dose and dose-rate assessments, for simulating sheltering, evacuation and milk interdiction, for estimating health effects and economic costs, and for evaluating action alternatives by means of a rule based system containing components of multi-attribute value techniques. The specially designed operating system has been developed on the basis of the client-server model as a transportable package to run on workstations with a standard based UNIX operating system, and an X-Window system. One of its key features is the support of integrated external software products developed by the contractors by providing standardized services, such as system control, data management and graphical presentation. A data base of geographical structures (e.g. landscape, buildings, traffic network) with an accuracy of 30 m stored as vector data and population distribution stored in a 1 kmx1 km grid allows the presentation and evaluation of results down to a high local resolution by a special graphics subsystem. (orig./DG)

  1. Real-time QRS detection using integrated variance for ECG gated cardiac MRI

    Directory of Open Access Journals (Sweden)

    Schmidt Marcus

    2016-09-01

    Full Text Available During magnetic resonance imaging (MRI, a patient’s vital signs are required for different purposes. In cardiac MRI (CMR, an electrocardiogram (ECG of the patient is required for triggering the image acquisition process. However, a reliable QRS detection of an ECG signal acquired inside an MRI scanner is a challenging task due to the magnetohydrodynamic (MHD effect which interferes with the ECG. The aim of this work was to develop a reliable QRS detector usable inside the MRI which also fulfills the standards for medical devices (IEC 60601-2-27. Therefore, a novel real-time QRS detector based on integrated variance measurements is presented. The algorithm was trained on ANSI/AAMI EC13 test waveforms and was then applied to two databases with 12-lead ECG signals recorded inside and outside an MRI scanner. Reliable results for both databases were achieved for the ECG signals recorded inside (DBMRI: sensitivity Se = 99.94%, positive predictive value +P = 99.84% and outside (DBInCarT: Se = 99.29%, +P = 99.72% the MRI. Due to the accurate R-peak detection in real-time this can be used for monitoring and triggering in MRI exams.

  2. Integrating real-time subsurface hydrologic monitoring with empirical rainfall thresholds to improve landslide early warning

    Science.gov (United States)

    Mirus, Benjamin B.; Becker, Rachel E.; Baum, Rex L.; Smith, Joel B.

    2018-01-01

    Early warning for rainfall-induced shallow landsliding can help reduce fatalities and economic losses. Although these commonly occurring landslides are typically triggered by subsurface hydrological processes, most early warning criteria rely exclusively on empirical rainfall thresholds and other indirect proxies for subsurface wetness. We explore the utility of explicitly accounting for antecedent wetness by integrating real-time subsurface hydrologic measurements into landslide early warning criteria. Our efforts build on previous progress with rainfall thresholds, monitoring, and numerical modeling along the landslide-prone railway corridor between Everett and Seattle, Washington, USA. We propose a modification to a previously established recent versus antecedent (RA) cumulative rainfall thresholds by replacing the antecedent 15-day rainfall component with an average saturation observed over the same timeframe. We calculate this antecedent saturation with real-time telemetered measurements from five volumetric water content probes installed in the shallow subsurface within a steep vegetated hillslope. Our hybrid rainfall versus saturation (RS) threshold still relies on the same recent 3-day rainfall component as the existing RA thresholds, to facilitate ready integration with quantitative precipitation forecasts. During the 2015–2017 monitoring period, this RS hybrid approach has an increase of true positives and a decrease of false positives and false negatives relative to the previous RA rainfall-only thresholds. We also demonstrate that alternative hybrid threshold formats could be even more accurate, which suggests that further development and testing during future landslide seasons is needed. The positive results confirm that accounting for antecedent wetness conditions with direct subsurface hydrologic measurements can improve thresholds for alert systems and early warning of rainfall-induced shallow landsliding.

  3. Real-Life Solutions to Real-Life Problems: Collaborating with a Non-Profit Foundation to Engage Honors Students in Applied Research

    Science.gov (United States)

    Stark, Emily

    2013-01-01

    Colleges and universities have long emphasized undergraduate research experiences as valuable activities for students. Collegiate honors programs in particular have embraced the role of student research as an integral experience for high-ability students, leading the way in developing the thesis-based model of undergraduate research that is…

  4. Instruments for radiation measurement in life sciences (5). Development of imaging technology in life science. 4. Real-time bioradiography

    International Nuclear Information System (INIS)

    Sasaki, Toru; Iwamoto, Akinori; Tsuboi, Hisashi; Katoh, Toru; Kudo, Hiroyuki; Kazawa, Erito; Watanabe, Yasuyoshi

    2006-01-01

    Real-time bioradiography, new bioradiography method, can collect and produce image of metabolism and function of cell in real-time. The principles of instrumentation, development process and the application examples of neuroscience and biomedical gerontology are stated. The bioradiography method, the gas-tissue live-cell autoradiography method and the real-time bioradiography method are explained. As the application examples, the molecular mechanism of oxidative stress at brain ischemia and the analysis of SOD gene knockout animals are reported. Comparison between FDG-PET of epileptic brain and FDG- bioradiography image of live-cell of brain tissue, the real-time bioradiography system, improvement of image by surface treatment, the detection limit of β + ray from F 18 , image of living-slices of brain tissue by FDG-real-time bioradiography and radioluminography, continuous FDG image of living-slices of rat brain tissue, and analysis of carbohydrate metabolism of living-slices of brain tissue of mouse lacking SOD gene during aerophobia and reoxygenation process are reported. (S.Y.)

  5. Motivational valence alters memory formation without altering exploration of a real-life spatial environment.

    Science.gov (United States)

    Chiew, Kimberly S; Hashemi, Jordan; Gans, Lee K; Lerebours, Laura; Clement, Nathaniel J; Vu, Mai-Anh T; Sapiro, Guillermo; Heller, Nicole E; Adcock, R Alison

    2018-01-01

    motivated learning implies that dissociable behavioral and biological mechanisms, here varying as a function of valence, contribute to memory outcomes in complex, real-life environments.

  6. Motivational valence alters memory formation without altering exploration of a real-life spatial environment.

    Directory of Open Access Journals (Sweden)

    Kimberly S Chiew

    characterization of motivated learning implies that dissociable behavioral and biological mechanisms, here varying as a function of valence, contribute to memory outcomes in complex, real-life environments.

  7. Immunosuppressive Drug Discontinuation in Noninfectious Uveitis From Real-Life Clinical Practice: A Survival Analysis.

    Science.gov (United States)

    Abásolo, Lydia; Rosales, Zulema; Díaz-Valle, David; Gómez-Gómez, Alejandro; Peña-Blanco, Rayma C; Prieto-García, Ángela; Benítez-Del-Castillo, José Manuel; Pato, Esperanza; García-Feijoo, Julián; Fernández-Gutiérrez, Benjamín; Rodriguez-Rodriguez, Luis

    2016-09-01

    To assess in uveitis patients the rate of immunosuppressive drug (ISD) discontinuation in real-life clinical practice, comparing this rate among ISDs. Longitudinal retrospective cohort study. We included uveitis patients attending a tertiary eye referral center from Madrid (Spain) between 1989 and 2015, prescribed any ISDs (cyclosporine, methotrexate, azathioprine, anti-TNF drugs, or others). Our main outcome was discontinuation of all ISDs owing to clinical efficacy, inefficacy, adverse drug reaction (ADR), and other medical causes. Discontinuation rates (DRs) per 100 patient-years were estimated. Variables associated with specific-cause discontinuations were analyzed using Cox bivariate and multivariate models. We analyzed 110 patients with 263 treatment courses and 665.2 patient-years of observation. Cyclosporine (66.4%), methotrexate (47.3%), azathioprine (30.9%), and anti-TNFs (30.9%) were the most frequently used ISDs. Treatment was suspended in 136 cases (mostly owing to clinical efficacy [38.2%], inefficacy [26.5%], and ADRs [22.8%]). All-cause DR with 95% confidence interval was 20.4 [17.3-24.2]. Retention rates at 1 and 10 years were 74% and 16%, respectively. In the multivariate analysis, combined treatment exhibited higher DRs owing to clinical efficacy than other ISDs in monotherapy. Conversely, nonbiologic combination therapy with azathioprine exhibited the highest DR owing to ADRs. Clinical efficacy was the most frequent cause for ISD discontinuation, followed by inefficacy and ADRs. DR owing to efficacy was higher for combination therapy. Furthermore, nonbiologic combination therapy with azathioprine was associated with a higher DR owing to ADRs. Copyright © 2016 Elsevier Inc. All rights reserved.

  8. Me, us, and them: Testing sociometer theory in a socially diverse real-life context.

    Science.gov (United States)

    Reitz, Anne K; Motti-Stefanidi, Frosso; Asendorpf, Jens B

    2016-06-01

    Although numerous studies have emphasized the role evaluations by others play for people's self-esteem, the perspective of others and the social diversity of real-life contexts have largely been ignored. In a large-scale longitudinal study, we examined the link between adolescents' self-esteem and their self- and peer-perceived popularity in socially diverse classrooms. First, we tested the competing directions of effects predicted by sociometer theory (i.e., peer-perceived popularity affects self-esteem, mediated by self-perceived popularity) and the self-broadcasting perspective (i.e., self-esteem affects peer-perceived popularity). Second, we examined differential effects of popularity in the own social group ("us") versus others ("them") by using immigrant status groups (i.e., immigrants versus host-nationals). We examined 1,057 13-year-old students in 3 annual waves. Cross-lagged analyses revealed that popularity among peers of the in-group but not among peers of the out-group prospectively predicted self-esteem, which was mediated by self-perceived popularity. Self-esteem in turn prospectively predicted self- but not peer-perceived popularity. In sum, the findings provide support for sociometer theory and a conscious sociometer mechanism but no support for the self-broadcasting perspective. The findings further demonstrate that the sociometer was more responsive to popularity in immigrant status in- than out-groups. In conclusion, the findings underscore the need to consider the perspective of others and their social group memberships to better understand the complexities of the link between self-esteem and popularity. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  9. Motivational valence alters memory formation without altering exploration of a real-life spatial environment

    Science.gov (United States)

    Hashemi, Jordan; Gans, Lee K.; Lerebours, Laura; Clement, Nathaniel J.; Vu, Mai-Anh T.; Sapiro, Guillermo; Heller, Nicole E.; Adcock, R. Alison

    2018-01-01

    motivated learning implies that dissociable behavioral and biological mechanisms, here varying as a function of valence, contribute to memory outcomes in complex, real-life environments. PMID:29558526

  10. Effects of omalizumab in severe asthmatics across ages: A real life Italian experience.

    Science.gov (United States)

    Sposato, B; Scalese, M; Latorre, M; Scichilone, N; Matucci, A; Milanese, M; Masieri, S; Rolla, G; Steinhilber, G; Rosati, Y; Vultaggio, A; Folletti, I; Baglioni, S; Bargagli, E; Di Tomassi, M; Pio, R; Pio, A; Maccari, U; Maggiorelli, C; Migliorini, M G; Vignale, L; Pulerà, N; Carpagnano, G E; Foschino Barbaro, M P; Perrella, A; Paggiaro, P L

    2016-10-01

    This retrospective study aimed at evaluating long-term effects of Omalizumab in elderly asthmatics in a real-life setting. 105 consecutive severe asthmatics (GINA step 4-5; mean FEV 1 % predicted:66 ± 15.7) treated with Omalizumab for at least 1 year (treatment mean duration 35.1 ± 21.7 months) were divided into 3 groups according to their age at Omalizumab treatment onset: 18-39, 40-64 and ≥ 65 years. Comorbidities, number of overweight/obese subjects and patients with late-onset asthma were more frequent among older people. A similar reduction of inhaled corticosteroids dosage and SABA on-demand therapy was observed in all groups during Omalizumab treatment; a similar FEV 1 increased was also observed. Asthma Control Test (ACT) improved significantly (p Omalizumab but the percentage of exacerbation-free patients was higher in younger people (76.9%) compared to middle aged patients (49.2%) and the elderly (29%) (p = 0.049). After Omalizumab treatment, the risk for exacerbations was lower in subjects aged 40-64 (OR = 0.284 [CI95% = 0.098-0.826], p = 0.021) and 18-39 (OR = 0.133 [CI95% = 0.026-0.678], p = 0.015), compared to elderly asthmatics. Also, a significantly reduced ACT improvement (β = -1.070; p = 0.046) passing from each age class was observed. Omalizumab improves all asthma outcomes independently of age, although the magnitude of the effects observed in the elderly seems to be lower than in the other age groups. Copyright © 2016 Elsevier Ltd. All rights reserved.

  11. Get the most from your data: a propensity score model comparison on real-life data

    Directory of Open Access Journals (Sweden)

    Ferdin

    2016-05-01

    Full Text Available Dennis Ferdinand,1 Mirko Otto,2 Christel Weiss1 1Department of Biomathematics and Medical Statistics, 2Department of Surgery, University Medical Center Mannheim (UMM, University of Heidelberg, Mannheim, Germany Purpose: In the past, the propensity score has been in the middle of several discussions in terms of its abilities and limitations. With a comprehensive review and a practical example, this study examines the effect of propensity score analysis of real-life data and introduces a simple and effective clinical approach. Materials and methods: After the authors reviewed current publications, they applied their insights to the data of a nonrandomized clinical trial in bariatric surgery. This study examined weight loss in 173 patients where 127 patients received Roux-en-Y gastric bypass surgery and 46 patients sleeve gastrectomy. Both groups underwent analysis in terms of their covariate distribution using Mann–Whitney U and χ2 testing. Mean differences within excess weight loss in native data were examined with Student’s t-test. Three propensity score models were defined and matching was performed. Covariate distribution and mean differences in excess weight loss were checked with Mann–Whitney U and χ2 testing. Results: Native data implied a significant difference in excess weight loss. The propensity score models did not confirm this difference. All models proved that both surgical procedures were equal, due to their weight-loss induction. Covariate distribution improved after the matching procedure in terms of an equal distribution. Conclusion: It seemed that a practical clinical approach with outcome-related covariates as a propensity score base is the ideal midpoint between an equal distribution in covariates and an acceptable loss of data. Nevertheless, propensity score models designed with clinical intent seemed to be absolutely suitable for overcoming heterogeneity in covariate distribution. Keywords: nonrandomized clinical

  12. Get the most from your data: a propensity score model comparison on real-life data.

    Science.gov (United States)

    Ferdinand, Dennis; Otto, Mirko; Weiss, Christel

    2016-01-01

    In the past, the propensity score has been in the middle of several discussions in terms of its abilities and limitations. With a comprehensive review and a practical example, this study examines the effect of propensity score analysis of real-life data and introduces a simple and effective clinical approach. After the authors reviewed current publications, they applied their insights to the data of a nonrandomized clinical trial in bariatric surgery. This study examined weight loss in 173 patients where 127 patients received Roux-en-Y gastric bypass surgery and 46 patients sleeve gastrectomy. Both groups underwent analysis in terms of their covariate distribution using Mann-Whitney U and χ (2) testing. Mean differences within excess weight loss in native data were examined with Student's t-test. Three propensity score models were defined and matching was performed. Covariate distribution and mean differences in excess weight loss were checked with Mann-Whitney U and χ (2) testing. Native data implied a significant difference in excess weight loss. The propensity score models did not confirm this difference. All models proved that both surgical procedures were equal, due to their weight-loss induction. Covariate distribution improved after the matching procedure in terms of an equal distribution. It seemed that a practical clinical approach with outcome-related covariates as a propensity score base is the ideal midpoint between an equal distribution in covariates and an acceptable loss of data. Nevertheless, propensity score models designed with clinical intent seemed to be absolutely suitable for overcoming heterogeneity in covariate distribution.

  13. Local contextual processing of abstract and meaningful real-life images in professional athletes.

    Science.gov (United States)

    Fogelson, Noa; Fernandez-Del-Olmo, Miguel; Acero, Rafael Martín

    2012-05-01

    We investigated the effect of abstract versus real-life meaningful images from sports on local contextual processing in two groups of professional athletes. Local context was defined as the occurrence of a short predictive series of stimuli occurring before delivery of a target event. EEG was recorded in 10 professional basketball players and 9 professional athletes of individual sports during three sessions. In each session, a different set of visual stimuli were presented: triangles facing left, up, right, or down; four images of a basketball player throwing a ball; four images of a baseball player pitching a baseball. Stimuli consisted of 15 % targets and 85 % of equal numbers of three types of standards. Recording blocks consisted of targets preceded by randomized sequences of standards and by sequences including a predictive sequence signaling the occurrence of a subsequent target event. Subjects pressed a button in response to targets. In all three sessions, reaction times and peak P3b latencies were shorter for predicted targets compared with random targets, the last most informative stimulus of the predictive sequence induced a robust P3b, and N2 amplitude was larger for random targets compared with predicted targets. P3b and N2 peak amplitudes were larger in the professional basketball group in comparison with professional athletes of individual sports, across the three sessions. The findings of this study suggest that local contextual information is processed similarly for abstract and for meaningful images and that professional basketball players seem to allocate more attentional resources in the processing of these visual stimuli.

  14. Dietary supplementation contributes to lifestyle improvement in hypercholesterolemic patients in real-life contexts.

    Science.gov (United States)

    Bruckert, E; Masana, L; Chapman, M J; Descamps, O; Bosi, E; Allaert, F A

    2014-07-01

    Assess the evolution of cardiovascular lifestyle behaviors in hypercholesterolemic patients concomitantly with changes in their daily intake of phytosterol-supplemented yoghurt (Phyto-SY). Nationwide prospective observational study conducted in general practices across France and Spain. Each practitioner suggested lifestyle changes to five consecutive patients with hypercholesterolemia (whether or not they were taking hypocholesterolemic drugs) and recommended daily consumption of Phyto-SY. The study design involved an inclusion visit, a patient's self-monitoring assessment after 1 month, and a final visit after 4 months. Primary evaluation criterion: changes in dietary habits assessed by a standardized Nutritional Lifestyle score. Secondary criteria: changes in lipid profile, anthropometry (waist circumference) and lifestyle behavior. A total of 2376 hypercholesterolemic patients (of whom 54.8% were women) were included. The average age was 56.2 years old. The Nutritional Lifestyle score improved from 15.4 ± 5.4 to 8.7 ± 4.0 (p 30 min) increased from 59.3% to 78.3% (p < 0.0001). The overweight rate decreased from 22.8% to 17.5% (p < 0.0001) and waist circumference from 94.6 ± 13.3 cm to 93.0 ± 12.8 cm (p < 0.0001). Nutritional Lifestyles and other lifestyle markers' improvement were parallel to adherence to Phyto-SY adherence. Improvements in Nutritional Lifestyle scores, which included regular consumption of Phyto-SY over 4 months, was significantly linked to healthier lifestyles and to beneficial modifications in atherogenic lipid profiles, which reflected patient empowerment in a 'real life' context.

  15. Embracing the role of real life studies in the management of rare cancers

    Directory of Open Access Journals (Sweden)

    Omar Abdel-Rahman

    2016-10-01

    Full Text Available For commonly occurring cancers, as well as situations or conditions that are frequently encountered in oncological setting, plenty of prospective data are available to oncologists or medical practitioners to facilitate the decision making process. However, for rare cancers and atypical scenarios, there are limited references in the current literature. Understandably, this is attributed to the difficulty in recruiting enough patients to systematically study such rare manifestations. Under these circumstances, the importance of real life data that are collected via population-based studies, case series, and case reports is especially significant. In the current issue of AMOR, the journal features three case reports that describe distinctly uncommon oncological scenarios. In one report, Vafaii and Shao highlighted the stepwise development of classical Hodgkin lymphoma (cHL from diffuse large B cell lymphoma (DLBCL via precursor Reed-Sternberg/Hodgkin cells, as confirmed via multiple biopsies. They suggested that cHL and DLBCL can be clonally related, even when developing metachronously in the same patient, based on the presence of a hybrid intermediate stage. Meanwhile, Xian and colleagues reported the surgical management of brachial plexus pain that is caused by Pancoast tumor. According to them, the condition closely resembles the symptoms of brachial plexus injury and thus, the underlying cause is easily misdiagnosed. Finally, Coehlo and co-workers presented a report on the prolonged disease control of esthesioneuroblastoma using a multimodality approach, combining surgery, radiotherapy, and chemotherapy to derive an effective treatment strategy. It is noteworthy that despite an initial distant metastasis setback, the patient responded positively to palliative chemotherapy, thus proving the value of the much debated approach.In short, these case reports are an invaluable addition to existing medical literature concerning the diagnoses and

  16. Life sciences payload definition and integration study, task C and D. Volume 2: Payload definition, integration, and planning studies

    Science.gov (United States)

    1973-01-01

    The Life Sciences Payload Definition and Integration Study was composed of four major tasks. Tasks A and B, the laboratory definition phase, were the subject of prior NASA study. The laboratory definition phase included the establishment of research functions, equipment definitions, and conceptual baseline laboratory designs. These baseline laboratories were designated as Maxi-Nom, Mini-30, and Mini-7. The outputs of Tasks A and B were used by the NASA Life Sciences Payload Integration Team to establish guidelines for Tasks C and D, the laboratory integration phase of the study. A brief review of Tasks A and B is presented provide background continuity. The tasks C and D effort is the subject of this report. The Task C effort stressed the integration of the NASA selected laboratory designs with the shuttle sortie module. The Task D effort updated and developed costs that could be used by NASA for preliminary program planning.

  17. Hearing the Messages: Integrating Pueblo Philosophy into Academic Life.

    Science.gov (United States)

    Lowery, Christine T.

    1997-01-01

    A Pueblo woman with a Ph.D. in social welfare research describes her academic journey, weaving a Pueblo cultural perspective into stories of the doctoral program, her dissertation research on life histories of Indian women recovering from substance abuse, her search for an academic position, the merit review ("a hostile act"), and her…

  18. Differences between clinical "snap-shot" and "real-life" assessments of lumbar spine alignment and motion - What is the "real" lumbar lordosis of a human being?

    Science.gov (United States)

    Dreischarf, Marcel; Pries, Esther; Bashkuev, Maxim; Putzier, Michael; Schmidt, Hendrik

    2016-03-21

    The individual lumbar lordosis and lumbar motion have been identified to play an important role in pathogenesis of low back pain and are essential references for preoperative planning and postoperative evaluation. The clinical "gold-standard" for measuring lumbar lordosis and its motion are radiological "snap-shots" taken while standing and during upper-body flexion and extension. The extent to which these clinically assessed values characterise lumbar alignment and its motion in daily life merits discussion. A non-invasive measurement-system was employed to measure lumbar lordosis and lumbar motion in 208 volunteers (age: 20-74yrs; ♀/♂: 115/93). For an initial short-term measurement, comparable with the clinical "snap-shot", lumbar lordosis and its motion were assessed while standing and during flexion and extension. Subsequently, volunteers were released to their daily lives while wearing the device, and measurements were performed during the following 24h. The average lumbar lordosis during 24h (8.0°) differed significantly from the standardised measurement while standing (33.3°). Ranges of motion were significantly different throughout the day compared to standing measurements. The influence of the factors age and gender on lordosis and its motion resulted in conflicting results between long- and short-term-measurements. In conclusion, results of short-term examinations differ considerably from the average values during real-life. These findings might be important for surgical planning and increase the awareness of the biomechanical challenges that spinal structures and implants face in real-life. Furthermore, long-term assessments of spinal alignment and motion during daily life can provide valid data on spinal function and can reveal the importance of influential factors. Copyright © 2016 Elsevier Ltd. All rights reserved.

  19. Flexible Conductive Composite Integrated with Personal Earphone for Wireless, Real-Time Monitoring of Electrophysiological Signs.

    Science.gov (United States)

    Lee, Joong Hoon; Hwang, Ji-Young; Zhu, Jia; Hwang, Ha Ryeon; Lee, Seung Min; Cheng, Huanyu; Lee, Sang-Hoon; Hwang, Suk-Won

    2018-06-14

    We introduce optimized elastomeric conductive electrodes using a mixture of silver nanowires (AgNWs) with carbon nanotubes/polydimethylsiloxane (CNTs/PDMS), to build a portable earphone type of wearable system that is designed to enable recording electrophysiological activities as well as listening to music at the same time. A custom-built, plastic frame integrated with soft, deformable fabric-based memory foam of earmuffs facilitates essential electronic components, such as conductive elastomers, metal strips, signal transducers and a speaker. Such platform incorporates with accessory cables to attain wireless, real-time monitoring of electrical potentials whose information can be displayed on a cell phone during outdoor activities and music appreciation. Careful evaluations on experimental results reveal that the performance of fabricated dry electrodes are comparable to that of commercial wet electrodes, and position-dependent signal behaviors provide a route toward accomplishing maximized signal quality. This research offers a facile approach for a wearable healthcare monitor via integration of soft electronic constituents with personal belongings.

  20. Development integration via real and technological convergence. Experience of Poland and conclusions for Ukraine

    Directory of Open Access Journals (Sweden)

    Michał G. Woźniak

    2014-09-01

    Full Text Available The paper summarizes main achievements, losses and gains during the first decade of Poland's membership in the EU, while also aiming at development of suggestions for the Polish economic policy in the years to come, as well as draws conclusions for Ukraine, which has now elected the strategy of international economic cooperation. The first part of the paper presents an empirical analysis of Poland's both real and technological convergence with the developed EU countries. These data show that since 1994, as the process of Poland integration with the EU commenced, our country significantly reduced the income and technology gap as compared to the EU. During the financial crisis, Poland 'felt' better than most European countries. In the second part of the paper we attempt to answer the question as to the current conditions of Polish economy development. It is demonstrated that Poland's economic success was due to multiple factors such as endogenous and exogenous, historical and those derived from present events. However, it can be assumed that integration with the EU has been an important positive factor in development of Poland during recent 20 years. Great importance was also vested in the implementation of economic reforms in Poland as well as in policy of the government, although not faultless. The last section of the paper identifies problems now faced by the EU and individual member states, including Poland as regards future years till 2020

  1. An accurate real-time model of maglev planar motor based on compound Simpson numerical integration

    Directory of Open Access Journals (Sweden)

    Baoquan Kou

    2017-05-01

    Full Text Available To realize the high-speed and precise control of the maglev planar motor, a more accurate real-time electromagnetic model, which considers the influence of the coil corners, is proposed in this paper. Three coordinate systems for the stator, mover and corner coil are established. The coil is divided into two segments, the straight coil segment and the corner coil segment, in order to obtain a complete electromagnetic model. When only take the first harmonic of the flux density distribution of a Halbach magnet array into account, the integration method can be carried out towards the two segments according to Lorenz force law. The force and torque analysis formula of the straight coil segment can be derived directly from Newton-Leibniz formula, however, this is not applicable to the corner coil segment. Therefore, Compound Simpson numerical integration method is proposed in this paper to solve the corner segment. With the validation of simulation and experiment, the proposed model has high accuracy and can realize practical application easily.

  2. An accurate real-time model of maglev planar motor based on compound Simpson numerical integration

    Science.gov (United States)

    Kou, Baoquan; Xing, Feng; Zhang, Lu; Zhou, Yiheng; Liu, Jiaqi

    2017-05-01

    To realize the high-speed and precise control of the maglev planar motor, a more accurate real-time electromagnetic model, which considers the influence of the coil corners, is proposed in this paper. Three coordinate systems for the stator, mover and corner coil are established. The coil is divided into two segments, the straight coil segment and the corner coil segment, in order to obtain a complete electromagnetic model. When only take the first harmonic of the flux density distribution of a Halbach magnet array into account, the integration method can be carried out towards the two segments according to Lorenz force law. The force and torque analysis formula of the straight coil segment can be derived directly from Newton-Leibniz formula, however, this is not applicable to the corner coil segment. Therefore, Compound Simpson numerical integration method is proposed in this paper to solve the corner segment. With the validation of simulation and experiment, the proposed model has high accuracy and can realize practical application easily.

  3. Using CASE-tools based on formal methods in real-life system development of distributed systems

    International Nuclear Information System (INIS)

    Stoelen, Ketil; Karlsen, Tore Willy; Mohn, Peter; Sandmark, Haaakon

    1998-03-01

    Within the OECD Halden Reactor Project (HRP) the development and application of formal methods to enhance system quality have been prioritised tasks for the last three years per periods. The three year programme 1997-1999 identifies the need to gain experience from applying formal methods in larger real-life system developments. This motivated the initiation of the HRP research activity Integration of Formal Specification in the Development of HAMMLAB 2000 (INT-FS). The principal objective of INT-FS is to experiment with formal methods in system developments connected to HAMMLAB 2000 and thereby gain a better understanding of their suitability to support practical software engineering. In particular, INT-FS will try to measure the effect of formal methods and gain experience in combining formal methods with traditional development techniques. INT-FS was started up in January 1997. This report describes the status of INT-FS by February 1998. The report identifies objectives and plans; it motivates the choice of formal methods, CASE-tool and software process; it motivates and defines metrics for measuring achievement and the effect of formalization. The report also provides preliminary results from an experimental development of a communication manager; it describes the component to be developed and the background of the participants; it offers some provisional statistics and summarises the experiences with methods and tools. The development of the communication manager is the first attempt ever to exploit state-of-the-art CASE-tools for formal methods in practical software engineering at the HRP. (author)

  4. Effect of different machining processes on the tool surface integrity and fatigue life

    Energy Technology Data Exchange (ETDEWEB)

    Cao, Chuan Liang [College of Mechanical and Electrical Engineering, Nanchang University, Nanchang (China); Zhang, Xianglin [School of Materials Science and Engineering, Huazhong University of Science and Technology, Wuhan (China)

    2016-08-15

    Ultra-precision grinding, wire-cut electro discharge machining and lapping are often used to machine the tools in fine blanking industry. And the surface integrity from these machining processes causes great concerns in the research field. To study the effect of processing surface integrity on the fine blanking tool life, the surface integrity of different tool materials under different processing conditions and its influence on fatigue life were thoroughly analyzed in the present study. The result shows that the surface integrity of different materials was quite different on the same processing condition. For the same tool material, the surface integrity on varying processing conditions was quite different too and deeply influenced the fatigue life.

  5. Let us Get Real! Integrated Approach for Virtual Coaching and Real Time Activity Monitoring in Lifestyle Change Support Systems

    NARCIS (Netherlands)

    Kulyk, Olga Anatoliyivna; op den Akker, Hendrikus J.A.; Klaassen, Randy; van Gemert-Pijnen, Julia E.W.C.; Hettinga, M; Smedberg, A

    There is a fast growing number of eHealth systems aiming at supporting a healthy lifestyle. Tailored lifestyle coaching services offer individual users access to web portals where they can communicate about a growing number of ingredients of everyday life concern: physical activity, nutrition,

  6. Turning points towards sustainability: integrative science and policy for novel (but real landscape futures

    Directory of Open Access Journals (Sweden)

    David J. Brunckhorst

    2004-09-01

    Full Text Available Non-metropolitan landscapes are the major theatre of interactions where large-scale alteration occurs precipitated by local to global forces of economic, social and environmental change. However, these regional landscape effects are critical also to local natural resource and social sustainability, ecosystem health through to larger scales of biospheric functioning. The institutions contributing pressures and responses consequently shape future landscapes and in turn influence how social systems, resource users, governments and policy makers perceive those landscapes and their future. These are, in essence, complex social-ecological systems intertwined in a multitude of ways at many spatial scales across time. Over time, the cycles of complex social-ecological systems also reach crossroads, which might be crisis points at which future options are no longer available (possibly because of resource degradation or loss, or turning points where opportunities arise when it is easier to change direction towards more sustainable activities. This paper provides some examples of interdisciplinary research that has provided a holistic integration through close engagement with residents and communities or through deliberately implementing integrative high-risk ‘on-ground’ experimental models to ‘learn by doing’. In the final analysis, each project has characteristically, however, sought to integrate through spatial (if not temporal synthesis, policy analysis and (new or changed institutional arrangements that are relevant locally and corporately, as well as at broader levels of government and geography. This has provided transferable outcomes that can contribute real options and adaptive capacity for suitable positive futures.

  7. Successful outsourcing: improving quality of life through integrated support services.

    Science.gov (United States)

    Bates, Jason; Sharratt, Martin; King, John

    2014-01-01

    This article examines the way that non-clinical support services are provided in healthcare settings through outsourcing partnerships. The integrated support services model and benefits to patient experience and safety as well as organizational efficiency and effectiveness are explored through an examination of services at a busy urban community hospital.

  8. Technology strategy for integrated operations and real time reservoir management; Technology Target Areas; TTA5 - Integrated operations and RTRM

    Energy Technology Data Exchange (ETDEWEB)

    2007-07-01

    In Norway Integrated Operations (IO) is a concept which in the first phase (G1) has been used to describe how to integrate processes and people onshore and offshore using ICT solutions and facilities that improve onshore's ability to support offshore operationally. The second generation (G2) Integrated Operations aims to help operators utilize vendors' core competencies and services more efficiently. Utilizing digital services and vendor products, operators will be able to update reservoir models, drilling targets and well trajectories as wells are drilled, manage well completions remotely, optimize production from reservoir to export lines, and implement condition-based maintenance concepts. The total impact on production, recovery rates, costs and safety will be profound. When the international petroleum business moves to the Arctic region the setting is very different from what is the case on the Norwegian Continental Shelf (NCS) and new challenges will arise. The Norwegian Ministry of Environment has recently issued an Integrated Management Plan for the Barents Sea where one focus is on 'Monitoring of the Marine Environment in the North'. The Government aims to establish a new and more coordinated system for monitoring the marine ecosystems in the north. A representative group consisting of the major Operators, the Service Industry, Academia and the Authorities have developed the enclosed strategy for the OG21 Integrated Operations and Real Time Reservoir Management (IO and RTRM) Technology Target Area (TTA). Major technology and work process research and development gaps have been identified in several areas: Bandwidth down-hole to surface; Sensor development including Nano-technology; Cross discipline use of Visualisation, Simulation and model development particularly in Drilling and Reservoir management areas; Software development in terms of data handling, model updating and calculation speed; Enabling reliable and robust communications particularly for

  9. Technology strategy for integrated operations and real time reservoir management; Technology Target Areas; TTA5 - Integrated operations and RTRM

    Energy Technology Data Exchange (ETDEWEB)

    2007-07-01

    In Norway Integrated Operations (IO) is a concept which in the first phase (G1) has been used to describe how to integrate processes and people onshore and offshore using ICT solutions and facilities that improve onshore's ability to support offshore operationally. The second generation (G2) Integrated Operations aims to help operators utilize vendors' core competencies and services more efficiently. Utilizing digital services and vendor products, operators will be able to update reservoir models, drilling targets and well trajectories as wells are drilled, manage well completions remotely, optimize production from reservoir to export lines, and implement condition-based maintenance concepts. The total impact on production, recovery rates, costs and safety will be profound. When the international petroleum business moves to the Arctic region the setting is very different from what is the case on the Norwegian Continental Shelf (NCS) and new challenges will arise. The Norwegian Ministry of Environment has recently issued an Integrated Management Plan for the Barents Sea where one focus is on 'Monitoring of the Marine Environment in the North'. The Government aims to establish a new and more coordinated system for monitoring the marine ecosystems in the north. A representative group consisting of the major Operators, the Service Industry, Academia and the Authorities have developed the enclosed strategy for the OG21 Integrated Operations and Real Time Reservoir Management (IO and RTRM) Technology Target Area (TTA). Major technology and work process research and development gaps have been identified in several areas: Bandwidth down-hole to surface; Sensor development including Nano-technology; Cross discipline use of Visualisation, Simulation and model development particularly in Drilling and Reservoir management areas; Software development in terms of data handling, model updating and calculation speed; Enabling reliable and robust communications

  10. Is fear in your head? A comparison of instructed and real-life expressions of emotion in the face and body.

    Science.gov (United States)

    Abramson, Lior; Marom, Inbal; Petranker, Rotem; Aviezer, Hillel

    2017-04-01

    The majority of emotion perception studies utilize instructed and stereotypical expressions of faces or bodies. While such stimuli are highly standardized and well-recognized, their resemblance to real-life expressions of emotion remains unknown. Here we examined facial and body expressions of fear and anger during real-life situations and compared their recognition to that of instructed expressions of the same emotions. In order to examine the source of the affective signal, expressions of emotion were presented as faces alone, bodies alone, and naturally, as faces with bodies. The results demonstrated striking deviations between recognition of instructed and real-life stimuli, which differed as a function of the emotion expressed. In real-life fearful expressions of emotion, bodies were far better recognized than faces, a pattern not found with instructed expressions of emotion. Anger reactions were better recognized from the body than from the face in both real-life and instructed stimuli. However, the real-life stimuli were overall better recognized than their instructed counterparts. These results indicate that differences between instructed and real-life expressions of emotion are prevalent and raise caution against an overreliance of researchers on instructed affective stimuli. The findings also demonstrate that in real life, facial expression perception may rely heavily on information from the contextualizing body. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  11. Long-term Course of Alzheimer Disease in Patients Treated According to the Dutch Dementia Guideline at a Memory Clinic A "Real-Life" Study

    NARCIS (Netherlands)

    Droogsma, Erika; van Asselt, Dieneke; van Steijn, Jolanda; Diekhuis, Marjolein; Veeger, Nic; De Deyn, Peter P.

    2016-01-01

    Introduction:There is little knowledge of the long-term course of Alzheimer disease (AD) in light of current pharmacological and nonpharmacological interventions provided in a real-life setting.Methods:The Frisian Alzheimer's Disease Cohort study is a real-life study of the course of AD in patients

  12. Can virtual reality exposure therapy gains be generalized to real-life? : A meta-analysis of studies applying behavioral assessments

    NARCIS (Netherlands)

    Morina, Nexhmedin; Ijntema, Hiske; Meyerbröker, Katharina; Emmelkamp, Paul M G

    2015-01-01

    In virtual reality exposure therapy (VRET), patients are exposed to virtual environments that resemble feared real-life situations. The aim of the current study was to assess the extent to which VRET gains can be observed in real-life situations. We conducted a meta-analysis of clinical trials

  13. Understanding future emissions from low-carbon power systems by integration of life-cycle assessment and integrated energy modelling

    Science.gov (United States)

    Pehl, Michaja; Arvesen, Anders; Humpenöder, Florian; Popp, Alexander; Hertwich, Edgar G.; Luderer, Gunnar

    2017-12-01

    Both fossil-fuel and non-fossil-fuel power technologies induce life-cycle greenhouse gas emissions, mainly due to their embodied energy requirements for construction and operation, and upstream CH4 emissions. Here, we integrate prospective life-cycle assessment with global integrated energy-economy-land-use-climate modelling to explore life-cycle emissions of future low-carbon power supply systems and implications for technology choice. Future per-unit life-cycle emissions differ substantially across technologies. For a climate protection scenario, we project life-cycle emissions from fossil fuel carbon capture and sequestration plants of 78-110 gCO2eq kWh-1, compared with 3.5-12 gCO2eq kWh-1 for nuclear, wind and solar power for 2050. Life-cycle emissions from hydropower and bioenergy are substantial (˜100 gCO2eq kWh-1), but highly uncertain. We find that cumulative emissions attributable to upscaling low-carbon power other than hydropower are small compared with direct sectoral fossil fuel emissions and the total carbon budget. Fully considering life-cycle greenhouse gas emissions has only modest effects on the scale and structure of power production in cost-optimal mitigation scenarios.

  14. Integration of lessons from recent research for “Earth to Mars” life support systems

    Science.gov (United States)

    Nelson, M.; Dempster, W. F.; Allen, J. P.

    Development of reliable and robust strategies for long-term life support for planetary exploration must be built from real-time experimentation to verify and improve system components. Also critical is incorporating a range of viable options to handle potential short-term life system imbalances. This paper revisits some of the conceptual framework for a Mars base prototype which has been developed by the authors along with others previously advanced ("Mars on Earth ®") in the light of three years of experimentation in the Laboratory Biosphere, further investigation of system alternatives and the advent of other innovative engineering and agri-ecosystem approaches. Several experiments with candidate space agriculture crops have demonstrated the higher productivity possible with elevated light levels and improved environmental controls. For example, crops of sweet potatoes exceeded original Mars base prototype projections by an average of 46% (53% for best crop) ultradwarf (Apogee) wheat by 9% (23% for best crop), pinto bean by 13% (31% for best crop). These production levels, although they may be increased with further optimization of lighting regimes, environmental parameters, crop density etc. offer evidence that a soil-based system can be as productive as the hydroponic systems which have dominated space life support scenarios and research. But soil also offers distinct advantages: the capability to be created on the Moon or Mars using in situ space resources, reduces long-term reliance on consumables and imported resources, and more readily recycling and incorporating crew and crop waste products. In addition, a living soil contains a complex microbial ecosystem which helps prevent the buildup of trace gases or compounds, and thus assist with air and water purification. The atmospheric dynamics of these crops were studied in the Laboratory Biosphere adding to the database necessary for managing the mixed stands of crops essential for supplying a nutritionally

  15. Real-time impact of power balancing on power system operation with large scale integration of wind power

    DEFF Research Database (Denmark)

    Basit, Abdul; Hansen, Anca Daniela; Sørensen, Poul Ejnar

    2017-01-01

    Highly wind power integrated power system requires continuous active power regulation to tackle the power imbalances resulting from the wind power forecast errors. The active power balance is maintained in real-time with the automatic generation control and also from the control room, where...... power system model. The power system model takes the hour-ahead regulating power plan from power balancing model and the generation and power exchange capacities for the year 2020 into account. The real-time impact of power balancing in a highly wind power integrated power system is assessed...

  16. Aircraft Engine Life-Consumption Monitoring for Real-Time Reliability Determination, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — The object of this research is to develop an in-service life-monitor system for the prediction of the remaining component and system life of aircraft engines. The...

  17. Neither Right nor Wrong: How a Teacher Integrates Her Personal and Professional Life with Policy

    Science.gov (United States)

    Bunten, Bridget A.

    2014-01-01

    This article focuses on the importance of recognizing and appreciating the ways that a teacher integrates her personal and professional life with an English-only policy. Much can be learned from the ways in which she negotiates social forces and integrates them into her individual reality while making sense of the restrictive language policy.…

  18. Natalizumab treatment reduces fatigue in multiple sclerosis. Results from the TYNERGY trial; a study in the real life setting

    DEFF Research Database (Denmark)

    Svenningsson, Anders; Falk, Eva; Celius, Elisabeth G

    2013-01-01

    . The TYNERGY study aimed to further evaluate the effects of natalizumab treatment on MS-related fatigue. In this one-armed clinical trial including 195 MS patients, natalizumab was prescribed in a real-life setting, and a validated questionnaire, the Fatigue Scale for Motor and Cognitive functions (FSMC......), was used both before and after 12 months of treatment to evaluate a possible change in the fatigue experienced by the patients. In the treated cohort all measured variables, that is, fatigue score, quality of life, sleepiness, depression, cognition, and disability progression were improved from baseline...

  19. Prospective validation of a near real-time EHR-integrated automated SOFA score calculator.

    Science.gov (United States)

    Aakre, Christopher; Franco, Pablo Moreno; Ferreyra, Micaela; Kitson, Jaben; Li, Man; Herasevich, Vitaly

    2017-07-01

    We created an algorithm for automated Sequential Organ Failure Assessment (SOFA) score calculation within the Electronic Health Record (EHR) to facilitate detection of sepsis based on the Third International Consensus Definitions for Sepsis and Septic Shock (SEPSIS-3) clinical definition. We evaluated the accuracy of near real-time and daily automated SOFA score calculation compared with manual score calculation. Automated SOFA scoring computer programs were developed using available EHR data sources and integrated into a critical care focused patient care dashboard at Mayo Clinic in Rochester, Minnesota. We prospectively compared the accuracy of automated versus manual calculation for a sample of patients admitted to the medical intensive care unit at Mayo Clinic Hospitals in Rochester, Minnesota and Jacksonville, Florida. Agreement was calculated with Cohen's kappa statistic. Reason for discrepancy was tabulated during manual review. Random spot check comparisons were performed 134 times on 27 unique patients, and daily SOFA score comparisons were performed for 215 patients over a total of 1206 patient days. Agreement between automatically scored and manually scored SOFA components for both random spot checks (696 pairs, κ=0.89) and daily calculation (5972 pairs, κ=0.89) was high. The most common discrepancies were in the respiratory component (inaccurate fraction of inspired oxygen retrieval; 200/1206) and creatinine (normal creatinine in patients with no urine output on dialysis; 128/1094). 147 patients were at risk of developing sepsis after intensive care unit admission, 10 later developed sepsis confirmed by chart review. All were identified before onset of sepsis with the ΔSOFA≥2 point criterion and 46 patients were false-positives. Near real-time automated SOFA scoring was found to have strong agreement with manual score calculation and may be useful for the detection of sepsis utilizing the new SEPSIS-3 definition. Copyright © 2017 Elsevier B.V. All

  20. Network-Based Real-time Integrated Fire Detection and Alarm (FDA) System with Building Automation

    Science.gov (United States)

    Anwar, F.; Boby, R. I.; Rashid, M. M.; Alam, M. M.; Shaikh, Z.

    2017-11-01

    Fire alarm systems have become increasingly an important lifesaving technology in many aspects, such as applications to detect, monitor and control any fire hazard. A large sum of money is being spent annually to install and maintain the fire alarm systems in buildings to protect property and lives from the unexpected spread of fire. Several methods are already developed and it is improving on a daily basis to reduce the cost as well as increase quality. An integrated Fire Detection and Alarm (FDA) systems with building automation was studied, to reduce cost and improve their reliability by preventing false alarm. This work proposes an improved framework for FDA system to ensure a robust intelligent network of FDA control panels in real-time. A shortest path algorithmic was chosen for series of buildings connected by fiber optic network. The framework shares information and communicates with each fire alarm panels connected in peer to peer configuration and declare the network state using network address declaration from any building connected in network. The fiber-optic connection was proposed to reduce signal noises, thus increasing large area coverage, real-time communication and long-term safety. Based on this proposed method an experimental setup was designed and a prototype system was developed to validate the performance in practice. Also, the distributed network system was proposed to connect with an optional remote monitoring terminal panel to validate proposed network performance and ensure fire survivability where the information is sequentially transmitted. The proposed FDA system is different from traditional fire alarm and detection system in terms of topology as it manages group of buildings in an optimal and efficient manner.Introduction

  1. Absent yet Present: On the Paradoxical Nature of Characters in Nabokov’s The Real Life of Sebastian Knight

    Directory of Open Access Journals (Sweden)

    Irina Marchesini

    2016-11-01

    Full Text Available The present research is focused on the theme of absence, an area of inquiry that might seem dominant in the field of Nabokov Studies. The analysis, which concentrates in particular on the key figures of the novel The Real Life of Sebastian Knight (1941, notably the narrator V. and the poet Sebastian Knight, interprets the characters’ construction through the paradigm of absence. Arguably, the construction of characters in The Real Life of Sebastian Knight is paradoxical: absence constitutes their essence at a core level, as it often happens in the context of the self-conscious genre. Moreover, absence plays a key role in characters’ design, linking them to all Nabokovian novels. However, despite their innermost ‘flatness’, to use Edward M. Forster’s terminology, they still appear to be ‘round’, i.e. plausible, mimetic figures.

  2. Integration of Work-life Issues with Respect to Female Employees

    Directory of Open Access Journals (Sweden)

    Jitendra Kumar Sharma

    2011-02-01

    Full Text Available Work-life integration issue has become an agenda of board room meetings across the globe especially in India. A working person has multiple roles to play at a time at personal as well as organizational fronts; each demanding different skills and anticipations. When such role demands overlap and get clashed, serious problems are faced by the employees. Moreover, in sales, the performance pressure is high leading to work stress reflected in personal life. This research paper is an attempt to delve into the issue of work-life integration issues with reference to young women working as school teachers in private schools of Mumbai.

  3. Impact of motor fluctuations on real-life gait in Parkinson's patients.

    Science.gov (United States)

    Silva de Lima, Ana Lígia; Evers, Luc J W; Hahn, Tim; de Vries, Nienke M; Daeschler, Margaret; Boroojerdi, Babak; Terricabras, Dolors; Little, Max A; Bloem, Bastiaan R; Faber, Marjan J

    2018-05-01

    People with PD (PWP) have an increased risk of becoming inactive. Wearable sensors can provide insights into daily physical activity and walking patterns. (1) Is the severity of motor fluctuations associated with sensor-derived average daily walking quantity? (2) Is the severity of motor fluctuations associated with the amount of change in sensor-derived walking quantity after levodopa intake? 304 Dutch PWP from the Parkinson@Home study were included. At baseline, all participants received a clinical examination. During the follow-up period (median: 97 days; 25-Interquartile range-IQR: 91 days, 75-IQR: 188 days), participants used the Fox Wearable Companion app and streamed smartwatch accelerometer data to a cloud platform. The first research question was assessed by linear regression on the sensor-derived mean time spent walking/day with the severity of fluctuations (MDS-UPDRS item 4.4) as independent variable, controlled for age and MDS-UPDRS part-III score. The second research question was assessed by linear regression on the sensor-derived mean post-levodopa walking quantity, with the sensor-derived mean pre-levodopa walking quantity and severity of fluctuations as independent variables, controlled for mean time spent walking per day, age and MDS-UPDRS part-III score. PWP spent most time walking between 8am and 1pm, summing up to 72 ± 39 (mean ± standard deviation) minutes of walking/day. The severity of motor fluctuations did not influence the mean time spent walking (B = 2.4 ± 1.9, p = 0.20), but higher age (B = -1.3 ± 0.3, p = motor symptoms (B = -0.6 ± 0.2, p motor fluctuations is not associated with changes in real-life walking patterns in mildly to moderate affected PWP. Copyright © 2018 Elsevier B.V. All rights reserved.

  4. A New Cuffless Device for Measuring Blood Pressure: A Real-Life Validation Study.

    Science.gov (United States)

    Schoot, Tessa S; Weenk, Mariska; van de Belt, Tom H; Engelen, Lucien J L P G; van Goor, Harry; Bredie, Sebastian J H

    2016-05-05

    Cuffless blood pressure (BP) monitoring devices, based on pulse transit time, are being developed as an easy-to-use, more convenient, fast, and relatively cheap alternative to conventional BP measuring devices based on cuff occlusion. Thereby they may provide a great alternative to BP self-measurement. The objective of our study was to evaluate the performance of the first release of the Checkme Health Monitor (Viatom Technology), a cuffless BP monitor, in a real-life setting. Furthermore, we wanted to investigate whether the posture of the volunteer and the position of the device relative to the heart level would influence its outcomes. Study volunteers fell into 3 BP ranges: high (>160 mmHg), normal (130-160 mmHg), and low (measurements were met according to the European Society of Hypertension International Protocol (ESH-IP) for the validation of BP measurement devices. After calibrating the Checkme device, we measured systolic BP with Checkme and a validated, oscillometric reference BP monitor (RM). Measurements were performed in randomized order both in supine and in sitting position, and with Checkme at and above heart level. We recruited 52 volunteers, of whom we excluded 15 (12 due to calibration failure with Checkme, 3 due to a variety of reasons). The remaining 37 volunteers were divided into low (n=14), medium (n=13), and high (n=10) BP ranges. There were 18 men and 19 women, with a mean age of 54.1 (SD 14.5) years, and mean recruitment systolic BP of 141.7 (SD 24.7) mmHg. BP results obtained by RM and Checkme correlated well. In the supine position, the difference between the RM and Checkme was >5 mmHg in 17 of 37 volunteers (46%), of whom 9 of 37 (24%) had a difference >10 mmHg and 5 of 37 (14%) had a difference >15 mmHg. BP obtained with Checkme correlated well with RM BP, particularly in the position (supine) in which the device was calibrated. These preliminary results are promising for conducting further research on cuffless BP measurement in the

  5. Integrating mental health services into primary HIV care for women: the Whole Life project.

    OpenAIRE

    Dodds, Sally; Nuehring, Elane M.; Blaney, Nancy T.; Blakley, Theresa; Lizzotte, Jean-Marie; Lopez, Myriam; Potter, JoNell E.; O'Sullivan, Mary J.

    2004-01-01

    The high rate of mental health problems in HIV-infected women jeopardizes the health of this vulnerable population, and constitutes a mandate for integrating mental health services into HIV primary care. The Whole Life project-a collaboration of the departments of Psychiatry and Obstetrics/Gynecology at the University of Miami School of Medicine-successfully integrated mental health services into primary HIV care for women. This article describes the conceptual framework of the integration, i...

  6. Measurement of Walking Ground Reactions in Real-Life Environments: A Systematic Review of Techniques and Technologies.

    Science.gov (United States)

    Shahabpoor, Erfan; Pavic, Aleksandar

    2017-09-12

    Monitoring natural human gait in real-life environments is essential in many applications, including quantification of disease progression, monitoring the effects of treatment, and monitoring alteration of performance biomarkers in professional sports. Nevertheless, developing reliable and practical techniques and technologies necessary for continuous real-life monitoring of gait is still an open challenge. A systematic review of English-language articles from scientific databases including Scopus, ScienceDirect, Pubmed, IEEE Xplore, EBSCO and MEDLINE were carried out to analyse the 'accuracy' and 'practicality' of the current techniques and technologies for quantitative measurement of the tri-axial walking ground reactions outside the laboratory environment, and to highlight their strengths and shortcomings. In total, 679 relevant abstracts were identified, 54 full-text papers were included in the paper and the quantitative results of 17 papers were used for meta-analysis and comparison. Three classes of methods were reviewed: (1) methods based on measured kinematic data; (2) methods based on measured plantar pressure; and (3) methods based on direct measurement of ground reactions. It was found that all three classes of methods have competitive accuracy levels with methods based on direct measurement of the ground reactions showing highest accuracy while being least practical for long-term real-life measurement. On the other hand, methods that estimate ground reactions using measured body kinematics show highest practicality of the three classes of methods reviewed. Among the most prominent technical and technological challenges are: (1) reducing the size and price of tri-axial load-cells; (2) improving the accuracy of orientation measurement using IMUs; (3) minimizing the number and optimizing the location of required IMUs for kinematic measurement; (4) increasing the durability of pressure insole sensors, and (5) enhancing the robustness and versatility of the

  7. Measurement of Walking Ground Reactions in Real-Life Environments: A Systematic Review of Techniques and Technologies

    Directory of Open Access Journals (Sweden)

    Erfan Shahabpoor

    2017-09-01

    Full Text Available Monitoring natural human gait in real-life environments is essential in many applications, including quantification of disease progression, monitoring the effects of treatment, and monitoring alteration of performance biomarkers in professional sports. Nevertheless, developing reliable and practical techniques and technologies necessary for continuous real-life monitoring of gait is still an open challenge. A systematic review of English-language articles from scientific databases including Scopus, ScienceDirect, Pubmed, IEEE Xplore, EBSCO and MEDLINE were carried out to analyse the ‘accuracy’ and ‘practicality’ of the current techniques and technologies for quantitative measurement of the tri-axial walking ground reactions outside the laboratory environment, and to highlight their strengths and shortcomings. In total, 679 relevant abstracts were identified, 54 full-text papers were included in the paper and the quantitative results of 17 papers were used for meta-analysis and comparison. Three classes of methods were reviewed: (1 methods based on measured kinematic data; (2 methods based on measured plantar pressure; and (3 methods based on direct measurement of ground reactions. It was found that all three classes of methods have competitive accuracy levels with methods based on direct measurement of the ground reactions showing highest accuracy while being least practical for long-term real-life measurement. On the other hand, methods that estimate ground reactions using measured body kinematics show highest practicality of the three classes of methods reviewed. Among the most prominent technical and technological challenges are: (1 reducing the size and price of tri-axial load-cells; (2 improving the accuracy of orientation measurement using IMUs; (3 minimizing the number and optimizing the location of required IMUs for kinematic measurement; (4 increasing the durability of pressure insole sensors, and (5 enhancing the robustness and

  8. Proposal for the 4th Workshop on Mobile Gaming, Mobile Life – Interweaving the Virtual and the Real

    OpenAIRE

    Grüter , Barbara; Mügge , Holger; Oppermann , Leif; Billinghurst , Mark

    2012-01-01

    Part 18: Mobile Gaming, Mobile Life - Interweaving the Virtual and the Real; International audience; Over the last few years we have witnessed the smartphone dominating the market, the rapid growth of mobile apps, a surge in mobile augmented reality and location-based apps, and burgeoning mobile communities. While mobile topics continue to provide rich research challenges, people and companies outside academia already use these apps regularly. This is due to the increased availability of affo...

  9. Plant life management in Belgium: an integrated project

    International Nuclear Information System (INIS)

    Wacquier, W.; Smet, M. de; Hennart, J.C.; Greer, J.L.; Breesch, Ch.; Havard, P.

    2001-01-01

    In Belgium, a specific plant life management project, named ''Continuous Operation of Belgian NPPs'' is currently developing. Its final objective is to centralize all safety and economic aspects of plant life management in order to determine, for each NPP unit, the optimal actions required to maintain their safe and reliable operation. As the lifetime of safety-related active components is permanently controlled by the current maintenance programs, the project focuses only on passive safety-related components and on non-safety components important for the availability of the plants. These structures and components were evaluated and compared on the basis of a set of weighted criteria in order to measure their criticality and to identify those which must be considered in the project. The selection and the ranking of those components is based on the KBM TM methodology (Knowledge Based Maintenance). This methodology facilitates the collection, formalization and exchange of know-how and gives immediate results thanks to a sequential and systematic step by step analysis. (author)

  10. Nonlinear Heart Rate Variability features for real-life stress detection. Case study: students under stress due to university examination.

    Science.gov (United States)

    Melillo, Paolo; Bracale, Marcello; Pecchia, Leandro

    2011-11-07

    This study investigates the variations of Heart Rate Variability (HRV) due to a real-life stressor and proposes a classifier based on nonlinear features of HRV for automatic stress detection. 42 students volunteered to participate to the study about HRV and stress. For each student, two recordings were performed: one during an on-going university examination, assumed as a real-life stressor, and one after holidays. Nonlinear analysis of HRV was performed by using Poincaré Plot, Approximate Entropy, Correlation dimension, Detrended Fluctuation Analysis, Recurrence Plot. For statistical comparison, we adopted the Wilcoxon Signed Rank test and for development of a classifier we adopted the Linear Discriminant Analysis (LDA). Almost all HRV features measuring heart rate complexity were significantly decreased in the stress session. LDA generated a simple classifier based on the two Poincaré Plot parameters and Approximate Entropy, which enables stress detection with a total classification accuracy, a sensitivity and a specificity rate of 90%, 86%, and 95% respectively. The results of the current study suggest that nonlinear HRV analysis using short term ECG recording could be effective in automatically detecting real-life stress condition, such as a university examination.

  11. Methods of modeling TCO residential real estate in the life cycles of buildings as a promising energy efficiency management tool

    Directory of Open Access Journals (Sweden)

    Kulakov Kirill

    2017-01-01

    Full Text Available Building and developing an affordable housing market is a huge challenge for Russia’s national economy. Today, the housing construction industry finds itself in a situation torn by a conflict caused by the simultaneous needs to minimize the housing construction costs in order to make housing more affordable for Russians and to increase the energy efficiency of the housing projects, which is associated with additional costs for developers. To find solutions to this contradictory situation, one needs new theoretical and practical approaches and economic tools. The global economic trend of managing goods and services on the basis of the value of goods and services over the life cycle is also manifested in the construction industry in Russia. The problem of forming a new economic thinking in the housing sector predetermines the perception of the value of housing not only as the price of purchased real estate, but as the equivalent of the total cost of ownership of real estate throughout its life cycle. This approach allows to compensate the initial rise in the cost of construction resulting from the introduction of energy-efficient technologies by savings in the operational phase of the life cycle of the property. In this regard, management of the total cost of real estate ownership based on energy modeling is of high research and practical relevance.

  12. Drop-out rate among patients treated with omalizumab for severe asthma: Literature review and real-life experience.

    Science.gov (United States)

    Caminati, M; Senna, G; Stefanizzi, G; Bellamoli, R; Longhi, S; Chieco-Bianchi, F; Guarnieri, G; Tognella, S; Olivieri, M; Micheletto, C; Festi, G; Bertocco, E; Mazza, M; Rossi, A; Vianello, A

    2016-08-25

    In patients with asthma, particularly severe asthma, poor adherence to inhaled drugs negatively affects the achievement of disease control. A better adherence rate is expected in the case of injected drugs, such as omalizumab, as they are administered only in a hospital setting. However, adherence to omalizumab has never been systematically investigated. The aim of this study was to review the omalizumab drop-out rate in randomized controlled trials (RCTs) and real-life studies. A comparative analysis was performed between published data and the Italian North East Omalizumab Network (NEONet) database. In RCTs the drop-out rate ranged from 7.1 to 19.4 %. Although the reasons for withdrawal were only occasionally reported, patient decision and adverse events were the most frequently reported causes. In real-life studies the drop-out rate ranged from 0 to 45.5 %. In most cases lack of efficacy was responsible for treatment discontinuation. According to NEONet data, 32 % of treated patients dropped out, with an increasing number of drop outs observed over time. Patient decision and lack of efficacy accounted for most treatment withdrawals. Treatment adherence is particularly crucial in patients with severe asthma considering the clinical impact of the disease and the cost of non-adherence. The risk of treatment discontinuation has to be carefully considered both in the experimental and real-life settings. Increased knowledge regarding the main reasons for patient withdrawal is important to improve adherence in clinical practice.

  13. A Delphi Study to Detect Deficiencies and Propose Actions in Real Life Treatment of Neovascular Age-Related Macular Degeneration

    Directory of Open Access Journals (Sweden)

    Alfredo García-Layana

    2014-01-01

    Full Text Available Purpose. Spanish retina specialists were surveyed in order to propose actions to decrease deficiencies in real-life neovascular age macular degeneration treatment (nv-AMD. Methods. One hundred experts, members of the Spanish Vitreoretinal Society (SERV, were invited to complete an online survey of 52 statements about nv-AMD management with a modified Delphi methodology. Four rounds were performed using a 5-point Linkert scale. Recommendations were developed after analyzing the differences between the results and the SERV guidelines recommendations. Results. Eighty-seven specialists completed all the Delphi rounds. Once major potential deficiencies in real-life nv-AMD treatment were identified, 15 recommendations were developed with a high level of agreement. Consensus statements to reduce the burden of the disease included the use of treat and extend regimen and to reduce the amount of diagnostic tests during the loading phase and training technical staff to perform these tests and reduce the time between relapse detection and reinjection, as well as establishing patient referral protocols to outside general ophthalmology clinics. Conclusion. The level of agreement with the final recommendations for nv-AMD treatment among Spanish retinal specialist was high indicating that some actions could be applied in order to reduce the deficiencies in real-life nv-AMD treatment.

  14. Self-disclosure through weblogs and perceptions of online and "real-life" friendships among female bloggers.

    Science.gov (United States)

    Bane, Cynthia M H; Cornish, Marilyn; Erspamer, Nicole; Kampman, Lia

    2010-04-01

    The current study examined female bloggers' perceptions of online and "real-life" same-sex friendships and examined relationships between self-disclosure through blogs and perceptions of the two types of friendships. Three hundred seven female bloggers (M age = 34.56 years) completed an online survey regarding friendship satisfaction and perceptions of intimacy-promoting interaction patterns in friendships. One hundred respondents' weblogs were analyzed for self-disclosure. Self-reported self-disclosure was positively correlated with number of online friendships and satisfaction with online friendships. Although participants reported having close online friends, they perceived real-life friendships as more likely than online friendships to possess intimacy-promoting interaction patterns. These perceptions did not differ as a function of self-disclosure through blogging, although bloggers who were categorized as higher in disclosure were more satisfied with online friendships than were bloggers who were categorized as lower in disclosure. These results suggest a relationship between self-disclosure through blogging and online relationship satisfaction among women in middle adulthood but that these women perceive real-life friendships as more likely to offer interaction patterns that foster intimacy.

  15. Second life battery energy storage system for enhancing renewable energy grid integration

    DEFF Research Database (Denmark)

    Koch-Ciobotaru, C.; Saez-de-Ibarra, A.; Martinez-Laserna, E.

    2015-01-01

    of a second life battery energy storage system (SLBESS) and secondly, to obtain the power exchange and battery state of charge profiles during the operation. These will constitute the cycling patterns for testing batteries and studying the ageing effect of this specific application. Real data from the Spanish...... electricity market for a whole year are used for validating the results....

  16. Work-life integration in neuropsychology: a review of the existing literature and preliminary recommendations.

    Science.gov (United States)

    Feigon, Maia; Block, Cady; Guidotti Breting, Leslie; Boxley, Laura; Dawson, Erica; Cobia, Derin

    2018-02-01

    The purpose of the current review paper is to identify and describe challenges to work-life integration in neuropsychology, and from this review extrapolate an initial set of recommendations and present a set of scenarios in which the recommendations might apply in the hopes of improving quality of life for current and prospective neuropsychologists. Specific areas of focus include diversity, early and mid-career transitions, and potential barriers to advancement in specific practice settings. A broad review was conducted of extant literature on work-life integration. There is scant scientific literature in this area that is specific to neuropsychologists, or even psychology as a whole. Subsequently, the majority of this review was collected from more developed literatures in business and medical fields. The authors then provided recommendations based on experiences in their respective careers. Attempts were made to promote generalizability of recommendations for neuropsychologists in different settings. Evidence supports a potentially adverse impact on quality of life and overall life satisfaction when work and personal lives conflict. This manuscript identifies some of the potential risks when work and life responsibilities are not well integrated. It is anticipated this will serve as a catalyst for future studies on work-life integration in the field of neuropsychology, specifically.

  17. Real-time seismic monitoring of the integrated cape girardeau bridge array and recorded earthquake response

    Science.gov (United States)

    Celebi, M.

    2006-01-01

    This paper introduces the state of the art, real-time and broad-band seismic monitoring network implemented for the 1206 m [3956 ft] long, cable-stayed Bill Emerson Memorial Bridge in Cape Girardeau (MO), a new Mississippi River crossing, approximately 80 km from the epicentral region of the 1811-1812 New Madrid earthquakes. The bridge was designed for a strong earthquake (magnitude 7.5 or greater) during the design life of the bridge. The monitoring network comprises a total of 84 channels of accelerometers deployed on the superstructure, pier foundations and at surface and downhole free-field arrays of the bridge. The paper also presents the high quality response data obtained from the network. Such data is aimed to be used by the owner, researchers and engineers to assess the performance of the bridge, to check design parameters, including the comparison of dynamic characteristics with actual response, and to better design future similar bridges. Preliminary analyses of ambient and low amplitude small earthquake data reveal specific response characteristics of the bridge and the free-field. There is evidence of coherent tower, cable, deck interaction that sometimes results in amplified ambient motions. Motions at the lowest tri-axial downhole accelerometers on both MO and IL sides are practically free from any feedback from the bridge. Motions at the mid-level and surface downhole accelerometers are influenced significantly by feedback due to amplified ambient motions of the bridge. Copyright ASCE 2006.

  18. Real life cost and quality of life associated with continuous intraduodenal levodopa infusion compared with oral treatment in Parkinson patients

    DEFF Research Database (Denmark)

    Lundqvist, C.; Beiske, A. G.; Reiertsen, O.

    2014-01-01

    Advanced-stage Parkinson's disease (PD) strongly affects quality of life (QoL). Continuous intraduodenal administration of levodopa (IDL) is efficacious, but entails high costs. This study aims to estimate these costs in routine care. 10 patients with advanced-PD who switched from oral medication...... was the dominant cost during IDL (45 % of total costs), it represented only 6.4 % of the total for conventional treatment. IDL improves function but is not cost effective using recommended thresholds for cost/QALY in Norway.......Advanced-stage Parkinson's disease (PD) strongly affects quality of life (QoL). Continuous intraduodenal administration of levodopa (IDL) is efficacious, but entails high costs. This study aims to estimate these costs in routine care. 10 patients with advanced-PD who switched from oral medication...... to IDL were assessed at baseline, and subsequently at 3, 6, 9 and 12 months follow-up. We used the Unified PD Rating Scale (UPDRS) for function and 15D for Quality of Life (QoL). Costs were assessed using quarterly structured patient questionnaires and hospital registries. Costs per quality adjusted life...

  19. How to integrate proxy data from two informants in life event assessment in psychological autopsy.

    Science.gov (United States)

    Zhang, Jie; Wang, Youqing; Fang, Le

    2018-04-27

    Life event assessment is an important part in psychological autopsy, and how to integrate its proxy data from two informants is a major methodological issue which needs solving. Totally 416 living subjects and their two informants were interviewed by psychological autopsy, and life events were assessed with Paykel's Interview for Recent Life Events. Validities of integrated proxy data using six psychological autopsy information reconstruction methods were evaluated, with living subjects' self-reports used as gold-standard criteria. For all the life events, average value of Youden Indexes for proxy data by type C information reconstruction method (choosing positive value from two informants) was larger than other five methods'. For family life related events, proxy data by type 1st information reconstruction method were not significantly different from living subjects' self-reports (P = 0.828). For all other life events, proxy data by type C information reconstruction method were not significantly different from the gold-standard. Choosing positive value is a relatively better method for integrating dichotomous (positive vs. negative) proxy data from two informants in life event assessment in psychological autopsy, except for family life related events. In that case, using information provided by 1st informants (mainly family member) is recommended.

  20. ELT-scale Adaptive Optics real-time control with thes Intel Xeon Phi Many Integrated Core Architecture

    Science.gov (United States)

    Jenkins, David R.; Basden, Alastair; Myers, Richard M.

    2018-05-01

    We propose a solution to the increased computational demands of Extremely Large Telescope (ELT) scale adaptive optics (AO) real-time control with the Intel Xeon Phi Knights Landing (KNL) Many Integrated Core (MIC) Architecture. The computational demands of an AO real-time controller (RTC) scale with the fourth power of telescope diameter and so the next generation ELTs require orders of magnitude more processing power for the RTC pipeline than existing systems. The Xeon Phi contains a large number (≥64) of low power x86 CPU cores and high bandwidth memory integrated into a single socketed server CPU package. The increased parallelism and memory bandwidth are crucial to providing the performance for reconstructing wavefronts with the required precision for ELT scale AO. Here, we demonstrate that the Xeon Phi KNL is capable of performing ELT scale single conjugate AO real-time control computation at over 1.0kHz with less than 20μs RMS jitter. We have also shown that with a wavefront sensor camera attached the KNL can process the real-time control loop at up to 966Hz, the maximum frame-rate of the camera, with jitter remaining below 20μs RMS. Future studies will involve exploring the use of a cluster of Xeon Phis for the real-time control of the MCAO and MOAO regimes of AO. We find that the Xeon Phi is highly suitable for ELT AO real time control.

  1. An Integrated Real-Time Beamforming and Postfiltering System for Nonstationary Noise Environments

    Directory of Open Access Journals (Sweden)

    Gannot Sharon

    2003-01-01

    Full Text Available We present a novel approach for real-time multichannel speech enhancement in environments of nonstationary noise and time-varying acoustical transfer functions (ATFs. The proposed system integrates adaptive beamforming, ATF identification, soft signal detection, and multichannel postfiltering. The noise canceller branch of the beamformer and the ATF identification are adaptively updated online, based on hypothesis test results. The noise canceller is updated only during stationary noise frames, and the ATF identification is carried out only when desired source components have been detected. The hypothesis testing is based on the nonstationarity of the signals and the transient power ratio between the beamformer primary output and its reference noise signals. Following the beamforming and the hypothesis testing, estimates for the signal presence probability and for the noise power spectral density are derived. Subsequently, an optimal spectral gain function that minimizes the mean square error of the log-spectral amplitude (LSA is applied. Experimental results demonstrate the usefulness of the proposed system in nonstationary noise environments.

  2. Real-Time Tracking of Parental Histones Reveals Their Contribution to Chromatin Integrity Following DNA Damage.

    Science.gov (United States)

    Adam, Salomé; Dabin, Juliette; Chevallier, Odile; Leroy, Olivier; Baldeyron, Céline; Corpet, Armelle; Lomonte, Patrick; Renaud, Olivier; Almouzni, Geneviève; Polo, Sophie E

    2016-10-06

    Chromatin integrity is critical for cell function and identity but is challenged by DNA damage. To understand how chromatin architecture and the information that it conveys are preserved or altered following genotoxic stress, we established a system for real-time tracking of parental histones, which characterize the pre-damage chromatin state. Focusing on histone H3 dynamics after local UVC irradiation in human cells, we demonstrate that parental histones rapidly redistribute around damaged regions by a dual mechanism combining chromatin opening and histone mobilization on chromatin. Importantly, parental histones almost entirely recover and mix with new histones in repairing chromatin. Our data further define a close coordination of parental histone dynamics with DNA repair progression through the damage sensor DDB2 (DNA damage-binding protein 2). We speculate that this mechanism may contribute to maintaining a memory of the original chromatin landscape and may help preserve epigenome stability in response to DNA damage. Copyright © 2016 The Author(s). Published by Elsevier Inc. All rights reserved.

  3. Life cycle assessment of roof integrated solar cell systems

    International Nuclear Information System (INIS)

    Van Brummelen, M.; Nieuwlaar, E.

    1994-01-01

    The research protocol, applied in this report, is designed for use within the energy R and D-context: it provides a framework for finding bottlenecks and opportunities for (new) energy technologies in the context of (energy) resource scarcity and environmental issues. Finding and analyzing these bottlenecks and opportunities is a major objective of this study. A derived objective of this study is to gain experience in using the LCA-framework and the research protocol described earlier, and to evaluate the usefulness of these instruments in helping to find and analyze bottlenecks and opportunities in energy technologies. Photovoltaic solar cell systems (PV systems) are comprised of solar cell modules and a Balance-of-System (BOS): a support structure and power conditioning equipment. In this LCA amorphous silicon cells (a-Si) are considered. For the Netherlands roof-integrated, grid-connected systems are assumed to be the major application of PV in the future. Two cases will be studied. In case 1 a system of 30 m 2 of modules which are connected to the grid via a single inverter are studied. The modules are comprised of a-Si cells and have a conversion efficiency of 10%. Integration into the roof is done with aluminium profiles. In case 2 a system of 30 m 2 a-Si cell modules integrated in the roof with plastic 'tiles' is studied. The modules have an efficiency of 15% and connection to the grid is more or less centralized: 25 systems share an inverter which is connected to the grid. The goal and scope of the LCA and the functional unit are described in chapter 2. In chapter 3 the process tree and descriptions of the distinguished processes are given and the inventory table is drawn up. In chapter 4 the impact assessment is dealt with, followed by a discussion of improvement options in chapter 5. Conclusions and recommendations are given in the chapters 6 and 7 only regarding the environmental aspects. 9 figs., 13 tabs., 4 appendices, 13 refs

  4. A new generation of real-time DOS technology for mission-oriented system integration and operation

    Science.gov (United States)

    Jensen, E. Douglas

    1988-01-01

    Information is given on system integration and operation (SIO) requirements and a new generation of technical approaches for SIO. Real-time, distribution, survivability, and adaptability requirements and technical approaches are covered. An Alpha operating system program management overview is outlined.

  5. Development of methodology for disability-adjusted life years (DALYs calculation based on real-life data.

    Directory of Open Access Journals (Sweden)

    Ellen A Struijk

    Full Text Available BACKGROUND: Disability-Adjusted Life Years (DALYs have the advantage that effects on total health instead of on a specific disease incidence or mortality can be estimated. Our aim was to address several methodological points related to the computation of DALYs at an individual level in a follow-up study. METHODS: DALYs were computed for 33,507 men and women aged 20-70 years when participating in the EPIC-NL study in 1993-7. DALYs are the sum of the Years Lost due to Disability (YLD and the Years of Life Lost (YLL due to premature mortality. Premature mortality was defined as death before the estimated date of individual Life Expectancy (LE. Different methods to compute LE were compared as well as the effect of different follow-up periods using a two-part model estimating the effect of smoking status on health as an example. RESULTS: During a mean follow-up of 12.4 years, there were 69,245 DALYs due to years lived with a disease or premature death. Current-smokers had lost 1.28 healthy years of their life (1.28 DALYs 95%CI 1.10; 1.46 compared to never-smokers. The outcome varied depending on the method used for estimating LE, completeness of disease and mortality ascertainment and notably the percentage of extinction (duration of follow-up of the cohort. CONCLUSION: We conclude that the use of DALYs in a cohort study is an appropriate way to assess total disease burden in relation to a determinant. The outcome is sensitive to the LE calculation method and the follow-up duration of the cohort.

  6. Relating the Learned Knowledge and Acquired Skills to Real Life: Function Sample

    Science.gov (United States)

    Albayrak, Mustafa; Yazici, Nurullah; Simsek, Mertkan

    2017-01-01

    Considering that Mathematics is a multidimensional problem-solving method that can be effective in all areas of cultural life, it is of great importance because of its contribution to other sciences such as physical and social sciences. It is known that the basic concepts of mathematics, which can also be expressed as a way of life, have helped to…

  7. A real-life, ecologically valid test of executive functioning : The executive secretarial task

    NARCIS (Netherlands)

    Lamberts, Kirsten F.; Evans, Jonathan J.; Spikman, Jacoba M.

    2010-01-01

    A major goal of neuropsychological assessment is predicting a person's level of functioning in daily life. Making predictions about everyday executive functioning based on tests is problematic because of the contrast between demands made in the test environment and demands made in everyday life

  8. Space Station Freedom environmental control and life support system phase 3 simplified integrated test detailed report

    Science.gov (United States)

    Roberts, B. C.; Carrasquillo, R. L.; Dubiel, M. Y.; Ogle, K. Y.; Perry, J. L.; Whitley, K. M.

    1990-01-01

    A description of the phase 3 simplified integrated test (SIT) conducted at the Marshall Space Flight Center (MSFC) Core Module Integration Facility (CMIF) in 1989 is presented. This was the first test in the phase 3 series integrated environmental control and life support systems (ECLSS) tests. The basic goal of the SIT was to achieve full integration of the baseline air revitalization (AR) subsystems for Space Station Freedom. Included is a description of the SIT configuration, a performance analysis of each subsystem, results from air and water sampling, and a discussion of lessons learned from the test. Also included is a full description of the preprototype ECLSS hardware used in the test.

  9. Integrated Process Modeling-A Process Validation Life Cycle Companion.

    Science.gov (United States)

    Zahel, Thomas; Hauer, Stefan; Mueller, Eric M; Murphy, Patrick; Abad, Sandra; Vasilieva, Elena; Maurer, Daniel; Brocard, Cécile; Reinisch, Daniela; Sagmeister, Patrick; Herwig, Christoph

    2017-10-17

    During the regulatory requested process validation of pharmaceutical manufacturing processes, companies aim to identify, control, and continuously monitor process variation and its impact on critical quality attributes (CQAs) of the final product. It is difficult to directly connect the impact of single process parameters (PPs) to final product CQAs, especially in biopharmaceutical process development and production, where multiple unit operations are stacked together and interact with each other. Therefore, we want to present the application of Monte Carlo (MC) simulation using an integrated process model (IPM) that enables estimation of process capability even in early stages of process validation. Once the IPM is established, its capability in risk and criticality assessment is furthermore demonstrated. IPMs can be used to enable holistic production control strategies that take interactions of process parameters of multiple unit operations into account. Moreover, IPMs can be trained with development data, refined with qualification runs, and maintained with routine manufacturing data which underlines the lifecycle concept. These applications will be shown by means of a process characterization study recently conducted at a world-leading contract manufacturing organization (CMO). The new IPM methodology therefore allows anticipation of out of specification (OOS) events, identify critical process parameters, and take risk-based decisions on counteractions that increase process robustness and decrease the likelihood of OOS events.

  10. Integration of manatee life-history data and population modeling

    Science.gov (United States)

    Eberhardt, L.L.; O'Shea, Thomas J.; O'Shea, Thomas J.; Ackerman, B.B.; Percival, H. Franklin

    1995-01-01

    Aerial counts and the number of deaths have been a major focus of attention in attempts to understand the population status of the Florida manatee (Trichechus manatus latirostris). Uncertainties associated with these data have made interpretation difficult. However, knowledge of manatee life-history attributes increased and now permits the development of a population model. We describe a provisional model based on the classical approach of Lotka. Parameters in the model are based on data from'other papers in this volume and draw primarily on observations from the Crystal River, Blue Spring, and Adantic Coast areas. The model estimates X (the finite rate ofincrease) at each study area, and application ofthe delta method provides estimates of variance components and partial derivatives ofX with respectto key input parameters (reproduction, adult survival, and early survival). In some study areas, only approximations of some parameters are available. Estimates of X and coefficients of variation (in parentheses) of manatees were 1.07 (0.009) in the Crystal River, 1.06 (0.012) at Blue Spring, and 1.01 (0.012) on the Atlantic Coast. Changing adult survival has a major effect on X. Early-age survival has the smallest effect. Bootstrap comparisons of population growth estimates from trend counts in the Crystal River and at Blue Spring and the reproduction and survival data suggest that the higher, observed rates from counts are probably not due to chance. Bootstrapping for variance estimates based on reproduction and survival data from manatees at Blue Spring and in the Crystal River provided estimates of X, adult survival, and rates of reproduction that were similar to those obtained by other methods. Our estimates are preliminary and suggestimprovements for future data collection and analysis. However, results support efforts to reduce mortality as the most effective means to promote the increased growth necessary for the eventual recovery of the Florida manatee

  11. An integrated approach to calculate life cycle costs of arms and military equipment

    Directory of Open Access Journals (Sweden)

    Vlada S. Sokolović

    2013-12-01

    , costs are one of the most dominant parameters in decision-making. Modern trends in this area comprehensively perceive all costs during the life cycle of assets.In general, in the analysis of costs in the life cycle of AME there are two sets of costs: visible and invisible (hidden costs. The visible part of the costs is mainly present in decision-making and usually includes the cost of equipping units or purchase of assets. The invisible part of the costs is far more significant. Although it is larger than the visible part and covers more groups of costs, decision-makers often do not take it into account. The hidden costs include: distribution costs, operating costs, maintenance costs, training costs, inventory costs, information systems costs, the cost of disposal and write-offs, etc. The decision making problem about investment in the AME purchase and equipping is obviously of  multicriteria nature, whether an optimum combination of costs for one  technical system (AME is in question, or whether it is a choice of a system of AME among many offered. COST ANALYSIS OF A PARTICULAR  ASSET For the illustration of an integrated approach to the analysis of the cost of assets in their life-cycle, a model from the US Naval Postgraduate School, was adjusted and applied on an example of a real asset. The model is applied to the case of two  squadrons of identical aircraft based at different airports. With regard to the availability, confidentiality, and the variability of costs and reliability of the elements of AME, the calculations in the model are implemented on the basis of the estimated or orientation parameters. Essentially, the goal is to demonstrate the interdependence, mutual relations and influences of parameters and their ultimate impact on the overall cost of military assets. Applying the model to a particular example points to the fact that, in the first years of asset life, the dominant cost is that of asset procurement (cost of acquisition, cost of assets

  12. Negative inferential style, emotional clarity, and life stress: integrating vulnerabilities to depression in adolescence.

    Science.gov (United States)

    Stange, Jonathan P; Alloy, Lauren B; Flynn, Megan; Abramson, Lyn Y

    2013-01-01

    Negative inferential style and deficits in emotional clarity have been identified as vulnerability factors for depression in adolescence, particularly when individuals experience high levels of life stress. However, previous research has not integrated these characteristics when evaluating vulnerability to depression. In the present study, a racially diverse community sample of 256 early adolescents (ages 12 and 13) completed a baseline visit and a follow-up visit 9 months later. Inferential style, emotional clarity, and depressive symptoms were assessed at baseline, and intervening life events and depressive symptoms were assessed at follow-up. Hierarchical linear regressions indicated that there was a significant three-way interaction between adolescents' weakest-link negative inferential style, emotional clarity, and intervening life stress predicting depressive symptoms at follow-up, controlling for initial depressive symptoms. Adolescents with low emotional clarity and high negative inferential styles experienced the greatest increases in depressive symptoms following life stress. Emotional clarity buffered against the impact of life stress on depressive symptoms among adolescents with negative inferential styles. Similarly, negative inferential styles exacerbated the impact of life stress on depressive symptoms among adolescents with low emotional clarity. These results provide evidence of the utility of integrating inferential style and emotional clarity as constructs of vulnerability in combination with life stress in the identification of adolescents at risk for depression. They also suggest the enhancement of emotional clarity as a potential intervention technique to protect against the effects of negative inferential styles and life stress on depression in early adolescence.

  13. Integrated bio-photonics to revolutionize health care enabled through PIX4life and PIXAPP

    Science.gov (United States)

    Jans, Hilde; O'Brien, Peter; Artundo, Iñigo; Porcel, Marco A. G.; Hoofman, Romano; Geuzebroek, Douwe; Dumon, Pieter; van der Vliet, Marcel; Witzens, Jeremy; Bourguignon, Eric; Van Dorpe, Pol; Lagae, Liesbet

    2018-02-01

    Photonics has become critical to life sciences. However, the field is far from benefiting fully from photonics' capabilities. Today, bulky and expensive optical systems dominate biomedical photonics, even though robust optical functionality can be realized cost-effectively on single photonic integrated circuits (PICs). Such chips are commercially available mostly for telecom applications, and at infrared wavelengths. Although proof-of-concept demonstrations for PICs in life sciences, using visible wavelengths are abundant, the gating factor for wider adoption is limited in resource capacity. Two European pilot lines, PIX4life and PIXAPP, were established to facilitate European R and D in biophotonics, by helping European companies and universities bridge the gap between research and industrial development. Through creation of an open-access model, PIX4life aims to lower barriers to entry for prototyping and validating biophotonics concepts for larger scale production. In addition, PIXAPP enables the assembly and packaging of photonic integrated circuits.

  14. Techno-economic feasibility study of the integration of a commercial small-scale ORC in a real case study

    International Nuclear Information System (INIS)

    Cavazzini, G.; Dal Toso, P.

    2015-01-01

    Highlights: • The integration of a small-scale commercial ORC in a real case study was analyzed. • The possibility of recovering the waste heat produced by an ICE was considered. • A semi-empirical steady-state model of the commercial small scale ORC was created. • Both direct and indirect costs was considered in the business model. • The ORC integration was not economically feasible due to increased indirect costs. - Abstract: The ORC certainly represents a promising solution for recovering low-grade waste heat in industries. However, the efficiency of commercial small-scale ORC solutions is still too low in comparison with the high initial costs of the machine and the lack of simulation models specifically developed for commercial ORC systems prevents industries from defining an accurate business model to correctly evaluate the ORC integration in real industrial processes. This paper presents a techno-economic feasibility analysis of the integration of a small-scale commercial ORC in a real case study, represented by a highly-efficient industrial distillery. The integration is aimed at maximizing the electricity auto-production by exploiting the heat produced by an internal combustion engine, already partially recovered in internal thermal processes. To analyze the influence of the ORC integration on the industrial processes, a semi-empirical steady-state model of the commercial small scale ORC was created. The model made it possible to simulate the performance of the commercial ORC within a hypothetical scenario involving the use of the heat from the cooling water and from the exhaust gases of the internal combustion engine. A detailed thermo-dynamic analysis has been carried out to study the effects of the ORC integration on the plant’s energy system with particular focus on the two processes directly affected by ORC integration, namely vapor production and the drying process of the grape marc. The analysis highlighted the great importance in the

  15. Career and Technology Center Guides Students in Real-Life Careers | Poster

    Science.gov (United States)

    By Carolynne Keenan, Contributing Writer Frederick County Public School students have a unique opportunity—a chance to get a real-world, hands-on experience in biomedical science and biotechnology before they even graduate from high school, thanks to the Frederick County Career and Technology Center (CTC). Several years ago, the CTC established its biomedical sciences program

  16. The Role of Real-Life Mathematics Instruction on Mathematics Outcomes in Kindergarten

    Science.gov (United States)

    Gottfried, Michael

    2016-01-01

    In an era of a declining quality and quantity of students entering and persisting in mathematics in the USA, researchers and policy makers are looking for new strategies to engage students in these fields and improve mathematics outcomes. One push has been to make mathematics instruction more relevant with real-world applications throughout the…

  17. Contracts in the Classroom--Providing Undergraduate Business Students with Important "Real Life" Skills

    Science.gov (United States)

    Denbo, Susan M.

    2005-01-01

    Many business law educators have recognized the importance of teaching students not only the rules of contract law, but the process of implementing these rules in the "real world" of business. This article discusses a contract negotiation exercise that enables students to apply the black letter law of contracts while at the same time honing their…

  18. Description of Anomalous Noise Events for Reliable Dynamic Traffic Noise Mapping in Real-Life Urban and Suburban Soundscapes

    Directory of Open Access Journals (Sweden)

    Francesc Alías

    2017-02-01

    Full Text Available Traffic noise is one of the main pollutants in urban and suburban areas. European authorities have driven several initiatives to study, prevent and reduce the effects of exposure of population to traffic. Recent technological advances have allowed the dynamic computation of noise levels by means of Wireless Acoustic Sensor Networks (WASN such as that developed within the European LIFE DYNAMAP project. Those WASN should be capable of detecting and discarding non-desired sound sources from road traffic noise, denoted as anomalous noise events (ANE, in order to generate reliable noise level maps. Due to the local, occasional and diverse nature of ANE, some works have opted to artificially build ANE databases at the cost of misrepresentation. This work presents the production and analysis of a real-life environmental audio database in two urban and suburban areas specifically conceived for anomalous noise events’ collection. A total of 9 h 8 min of labelled audio data is obtained differentiating among road traffic noise, background city noise and ANE. After delimiting their boundaries manually, the acoustic salience of the ANE samples is automatically computed as a contextual signal-to-noise ratio (SNR. The analysis of the real-life environmental database shows high diversity of ANEs in terms of occurrences, durations and SNRs, as well as confirming both the expected differences between the urban and suburban soundscapes in terms of occurrences and SNRs, and the rare nature of ANE.

  19. Real-Life Treatment Paradigms Show Adalimumab Is Cost-Effective for the Management of Ulcerative Colitis

    Directory of Open Access Journals (Sweden)

    Candace L. Beilman

    2016-01-01

    Full Text Available Background. Adalimumab is effective for the maintenance of remission in patients with moderate-to-severe ulcerative colitis (UC. Currently, biologic therapies are used in cases where patients fail conventional medical therapies. If biologic therapies are not available, patients often choose to remain in an unwell state rather than undergo colectomy. Objective. The aim of the study was to evaluate the cost-effectiveness of adalimumab in patients with UC where adalimumab was readily available compared to not available. Methods. A previously validated Markov model was used to simulate disease progression of patients with UC who are corticosteroid-dependent and/or did not respond to thiopurine therapy. Utility scores and transition probabilities between health states were determined by using data from randomized controlled trials and real-life observational studies. Costs were obtained from the Ontario Case Costing Initiative and the Alberta Health Schedule of Medical Benefits. Results. The incremental cost-effectiveness ratios for readily available adalimumab treatment of UC were $40,000 and $59,000 per quality-adjusted life year, compared with ongoing medical therapy in an unwell state, at 5-year and 10-year treatment time horizons, respectively. Conclusion. Considering real-life patient preferences to avoid colectomy, adalimumab is cost-effective according to a willingness-to-pay threshold of $80,000 for treatment of UC.

  20. Software life cycle management standards real-world solutions and scenarios for savings

    CERN Document Server

    Wright, David

    2011-01-01

    Software Life Cycle Management Standards will help you apply ISO/IEC 19770 to your business and enjoy the rewards it offers. David Wright calls on his vast experience to explain how the Standard applies to the whole of the software life cycle, not just the software asset management aspects. His informative guide gives up-to-date information using practical examples, clear diagrams and entertaining anecdotes.

  1. Integrated real-time control strategy in multi-tank A2O process for biological nutrient removal treating real domestic wastewater

    Directory of Open Access Journals (Sweden)

    Saad Abualhail

    2017-02-01

    Full Text Available An integrated real-time anaerobic–anoxic/oxic (A2O operated with multi-tank called IMT–A2O process was designed and operated with fluctuating influent loads for biological nutrient removal for treating real domestic wastewater. IMT–A2O process, a “phased isolation tank” technology, varies both aeration pattern and flow path in a continuous flow multi-tank system to force fluctuation of organic and nutrient concentrations in process reactors. Using an eight-phase cycle, desired biochemical transformations, are accomplished at different times in the same tank. On-line sensors (pH, ORP, and DO were used as real-time control parameters to adjust the duration of each operational phase in the IMT–A2O process. The control system is an algorithm that automatically adjusts the cycle length to the influent wastewater characteristics according to the end points. It was found that on-line sensor values of pH, ORP, and DO were somehow related with the dynamic behaviors of nutrient concentrations in IMT–A2O. The algorithm acts in the reaction phases of the IMT–A2O cycle using ORP and pH break points of tank one to distinguish the end of denitrification and the beginning of phosphorus release, pH break point of tank two to control the end of denitrification and beginning of phosphorus release and a sudden increase in DO pattern, pH break point and ORP to control phosphorus uptake and the end of the nitrification process. Although the fluctuations in raw wastewater concentration are extreme; an influent with a low C/N ratio is deficient in organic carbon, and a low carbon source level can limit the overall biological denitrification process, the average removal efficiencies achieved for COD, ammonia–nitrogen, total nitrogen and total phosphorus were not less than 76.11%, 87.78%, 76.45% and 83.75%, respectively, using the integrated real-time control strategy. The integrated IMT–A2O exhibited a better performance in nutrient removal than the

  2. Life sciences payload definition and integration study, task C and D. Volume 1: Management summary

    Science.gov (United States)

    1973-01-01

    The findings of a study to define the required payloads for conducting life science experiments in space are presented. The primary objectives of the study are: (1) identify research functions to be performed aboard life sciences spacecraft laboratories and necessary equipment, (2) develop conceptual designs of potential payloads, (3) integrate selected laboratory designs with space shuttle configurations, and (4) establish cost analysis of preliminary program planning.

  3. The sign problem in real-time path integral simulations: Using the cumulant action to implement multilevel blocking

    International Nuclear Information System (INIS)

    Mak, C. H.

    2009-01-01

    A practical method to tackle the sign problem in real-time path integral simulations is proposed based on the multilevel blocking idea. The formulation is made possible by using a cumulant expansion of the action, which in addition to addressing the sign problem, provides an unbiased estimator for the action from a statistically noisy sample of real-time paths. The cumulant formulation also allows the analytical gradients of the action to be computed with little extra computational effort, and it can easily be implemented in a massively parallel environment.

  4. Integrating RAMS engineering and management with the safety life cycle of IEC 61508

    International Nuclear Information System (INIS)

    Lundteigen, Mary Ann; Rausand, Marvin; Utne, Ingrid Bouwer

    2009-01-01

    This article outlines a new approach to reliability, availability, maintainability, and safety (RAMS) engineering and management. The new approach covers all phases of the new product development process and is aimed at producers of complex products like safety instrumented systems (SIS). The article discusses main RAMS requirements to a SIS and presents these requirements in a holistic perspective. The approach is based on a new life cycle model for product development and integrates this model into the safety life cycle of IEC 61508. A high integrity pressure protection system (HIPPS) for an offshore oil and gas application is used to illustrate the approach.

  5. Toward an Integrative Science of Life-Span Development and Aging

    Science.gov (United States)

    Piccinin, Andrea M.

    2010-01-01

    The study of aging demands an integrative life-span developmental framework, involving interdisciplinary collaborations and multiple methodological approaches for understanding how and why individuals change, in both normative and idiosyncratic ways. We highlight and summarize some of the issues encountered when conducting integrative research for understanding aging-related change, including, the integration of results across different levels of analysis; the integration of theory, design, and analysis; and the synthesis of results across studies of aging. We emphasize the necessity of longitudinal designs for understanding development and aging and discuss methodological issues that should be considered for achieving reproducible research on within-person processes. It will be important that current and future studies permit opportunities for quantitative comparison across populations given the extent to which historical shifts and cultural differences influence life-span processes and aging-related outcomes. PMID:20237144

  6. Systems Engineering and Integration for Advanced Life Support System and HST

    Science.gov (United States)

    Kamarani, Ali K.

    2005-01-01

    Systems engineering (SE) discipline has revolutionized the way engineers and managers think about solving issues related to design of complex systems: With continued development of state-of-the-art technologies, systems are becoming more complex and therefore, a systematic approach is essential to control and manage their integrated design and development. This complexity is driven from integration issues. In this case, subsystems must interact with one another in order to achieve integration objectives, and also achieve the overall system's required performance. Systems engineering process addresses these issues at multiple levels. It is a technology and management process dedicated to controlling all aspects of system life cycle to assure integration at all levels. The Advanced Integration Matrix (AIM) project serves as the systems engineering and integration function for the Human Support Technology (HST) program. AIM provides means for integrated test facilities and personnel for performance trade studies, analyses, integrated models, test results, and validated requirements of the integration of HST. The goal of AIM is to address systems-level integration issues for exploration missions. It will use an incremental systems integration approach to yield technologies, baselines for further development, and possible breakthrough concepts in the areas of technological and organizational interfaces, total information flow, system wide controls, technical synergism, mission operations protocols and procedures, and human-machine interfaces.

  7. Effects of Healthy Aging and Mild Cognitive Impairment on a Real-Life Decision-Making Task.

    Science.gov (United States)

    Pertl, Marie-Theres; Benke, Thomas; Zamarian, Laura; Delazer, Margarete

    2017-01-01

    In this study, we investigated the effects of age and of mild cognitive impairment (MCI) on decision making under risk by adopting a task representing real-life health-related situations and involving complex numerical information. Moreover, we assessed the relationship of real-life decision making to other cognitive functions such as number processing, executive functions, language, memory, and attention. For this reason, we compared the performance of 19 healthy, relatively younger adults with that of 18 healthy older adults and the performance of the 18 healthy older adults with that of 17 patients with MCI. Results indicated difficulties in real-life decision making for the healthy older adults compared with the healthy, relatively younger adults. Difficulties of patients with MCI relative to the healthy older adults arose in particular in difficult items requiring processing of frequencies and fractions. Significant effects of age and of MCI in processing frequencies were also evident in a ratio number comparison task. Decision-making performance of healthy participants and of the patient group correlated significantly with number processing. There was a further significant correlation with executive functions for the healthy participants and with reading comprehension for the patients. Our results suggest that healthy older individuals and patients with MCI make less advantageous decisions when the information is complex and high demands are put on executive functions and numerical abilities. Moreover, we show that executive functions and numerical abilities are not only essential in laboratory gambling tasks but also in more realistic and ecological decision situations within the health context.

  8. Deceleration during 'real life' motor vehicle collisions – a sensitive predictor for the risk of sustaining a cervical spine injury?

    Directory of Open Access Journals (Sweden)

    Hartwig Erich

    2009-03-01

    Full Text Available Abstract Background The predictive value of trauma impact for the severity of whiplash injuries has mainly been investigated in sled- and crash-test studies. However, very little data exist for real-life accidents. Therefore, the predictive value of the trauma impact as assessed by the change in velocity of the car due to the collision (ΔV for the resulting cervical spine injuries were investigated in 57 cases after real-life car accidents. Methods ΔV was determined for every car and clinical findings related to the cervical spine were assessed and classified according to the Quebec Task Force (QTF. Results In our study, 32 (56% subjects did not complain about symptoms and were therefore classified as QTF grade 0; 25 (44% patients complained of neck pain: 8 (14% were classified as QTF grade I, 6 (10% as QTF grade II, and 11 (19% as QTF grade IV. Only a slight correlation (r = 0.55 was found between the reported pain and ΔV. No relevant correlation was found between ΔV and the neck disability index (r = 0.46 and between ΔV and the QTF grade (r = 0.45 for any of the collision types. There was no ΔV threshold associated with acceptable sensitivity and specificity for the prognosis of a cervical spine injury. Conclusion The results of this study indicate that ΔV is not a conclusive predictor for cervical spine injury in real-life motor vehicle accidents. This is of importance for surgeons involved in medicolegal expertise jobs as well as patients who suffer from whiplash-associated disorders (WADs after motor vehicle accidents. Trial registration The study complied with applicable German law and with the principles of the Helsinki Declaration and was approved by the institutional ethics commission.

  9. [Required Framework for the Collection of Real-life Data: An Example from University Eye Hospital Munich].

    Science.gov (United States)

    Kortüm, Karsten; Kern, Christoph; Meyer, Gerhard; Priglinger, Siegfried; Hirneiß, Christoph

    2017-12-01

    Background The importance of evaluating real-life data is constantly increasing. Currently available computer systems better allow for analyses of data, as more and more data is available in a digital form. Before a project for real-life data analyses is started, technical considerations and staff, legal, and data protection procedures need to be addressed. In this manuscript, experiences made at the University Eye Hospital in Munich will be shared. Materials and Methods Legal requirements, as found in laws and guidelines governing documentation and data privacy, are highlighted. Technical requirements for information technology infrastructure and software are defined. A survey conducted by the German Ophthalmological Society, among German eye hospitals investigating the current state of digitalization, was conducted. Also, staff requirements are outlined. Results A database comprising results of 330,801 patients was set up. It includes all diagnoses, procedures, clinical findings and results from diagnostic devices. This database was approved by the local data protection officer. In less than half of German eye hospitals (n = 21) that participated in the survey (n = 54), a complete electronic documentation is done. Fourteen institutions are completely paper-based, and the remainder of the hospitals used a mixed system. Conclusion In this work, we examined the framework that is required to develop a comprehensive database containing real-life data from clinics. In future, these databases will become increasingly important as more and more innovation are made in decision support systems. The base for this is comprehensive and well-curated databases. Georg Thieme Verlag KG Stuttgart · New York.

  10. Psychosocial stress based on public speech in humans: is there a real life/laboratory setting cross-adaptation?

    Science.gov (United States)

    Jezova, D; Hlavacova, N; Dicko, I; Solarikova, P; Brezina, I

    2016-07-01

    Repeated or chronic exposure to stressors is associated with changes in neuroendocrine responses depending on the type, intensity, number and frequency of stress exposure as well as previous stress experience. The aim of the study was to test the hypothesis that salivary cortisol and cardiovascular responses to real-life psychosocial stressors related to public performance can cross-adapt with responses to psychosocial stress induced by public speech under laboratory setting. The sample consisted of 22 healthy male volunteers, which were either actors, more precisely students of dramatic arts or non-actors, students of other fields. The stress task consisted of 15 min anticipatory preparation phase and 15 min of public speech on an emotionally charged topic. The actors, who were accustomed to public speaking, responded with a rise in salivary cortisol as well as blood pressure to laboratory public speech. The values of salivary cortisol, systolic blood pressure and state anxiety were lower in actors compared to non-actors. Unlike non-actors, subjects with experience in public speaking did not show stress-induced rise in the heart rate. Evaluation of personality traits revealed that actors scored significantly higher in extraversion than the subjects in the non-actor group. In conclusion, neuroendocrine responses to real-life stressors in actors can partially cross-adapt with responses to psychosocial stress under laboratory setting. The most evident adaptation was at the level of heart rate responses. The public speech tasks may be of help in evaluation of the ability to cope with stress in real life in artists by simple laboratory testing.

  11. Real-Time PCR using a PCR Microchip with Integrated Thermal System and Polymer Waveguides for the Detection of Campylobacter jejuni

    DEFF Research Database (Denmark)

    Wang, Zhenyu; Sekulovic, Andrea; Kutter, Jörg Peter

    2006-01-01

    A novel real-time PCR microchip platform with integrated thermal system and polymer waveguides has been developed. By using the integrated optical system of the real-time PCR chip, cadF – a virulence gene of Campylobacter jejuni, could specifically be detected. Two different DNA binding dyes, SYTOX...

  12. Improvement in the quality of life of patients with chronic spontaneous urticaria treated with omalizumab in real life.

    Science.gov (United States)

    Larrea-Baca, Itzíar; Gurpegui-Resano, María

    Evaluation of the impact on the quality of life (QOL) relating to health in patients with chronic urticaria (CSU) treated with omalizumab. Longitudinal descriptive observational study of quality of life based on18 patients with chronic urticaria ≥12 years treated with omalizumab. Changes in QOL examined at 1 month (T1), at 6 months (T6) and 12 months (T12), by: Visual Analogical Scale (UAS), specific urticaria QOL questionnaire (CU-Q2oL), general health questionnaire (SF-36) and activity of urticaria questionnaire (Score UAS7). The most disabling symptoms for patients were: pruritus (61.1%); decrease in health and physical activity (55.5%), wheals, swelling and nervousness (50%); depression and shame of marks (38.89%); side effects to drugs (33.33%); sleepiness and tiredness (27.78%); work (22.22%); "choosing clothes and pain" 16.67% and social relations (11.11%). Statistically significant differences were observed in T1, T6 and T12. In T1, UAS -4.72 (p=.001); CU-Q2oL -16.38 (p<.001); SF-36 15.44 (p=.006); UAS7 wheals -7.27 (p=.001), UAS7 pruritus -8.72 (p=.003). In T6, UAS -4.26 (p=.001); CU-Q2oL -18.94 (p<.001); SF-36 15.41 (p<.001); UAS7 wheals -7.41 (p=.001), UAS7 pruritus -7.11 (p=.001). In T12 UAS -9.61 (p=.004); CU-Q2oL -21.38 (p=.01); SF-36 17.53 (p=.04); UAS7 wheals -8.23 (p=.004), UAS7 pruritus -10.69 (p=.004). There was a very good response in T1, which was maintained in T6 and T12. Patients with chronic urticaria treated with omalizumab presented good results with a reduction of CUE activity and improvement of their QOL. Copyright © 2017 Elsevier España, S.L.U. All rights reserved.

  13. Comparison of cortical activation during Mahjong game play in a video game setting and a real-life setting

    OpenAIRE

    Fujimori, Satomi; Terasawa, Koji; Murata, Yuki; Ogawa, Kishiko; Tabuchi, Hisaaki; Yanagisawa, Hiroki; Terasawa, Saiki; Shinohara, Kikunori; Yanagisawa, Akitaka

    2015-01-01

    The purpose of this study was to compare the hemodynamic changes that occur during Mahjong game play in virtual and real-life settings. Fourteen healthy right-handed men (average age ± standard deviation; 36.7 ± 14.9 years) played: 1) a Mahjong solitaire game on a video console against virtual rivals; 2) a Mahjong game against human opponents without conversation; and 3) a Mahjong game against human opponents with conversation. We measured oxygenated hemoglobin concentration at 44 locations o...

  14. Healthy food choices are happy food choices : evidence from a real life sample using smartphone based assessments

    OpenAIRE

    Wahl, Deborah R.; Villinger, Karoline; König, Laura M.; Ziesemer, Katrin; Schupp, Harald T.; Renner, Britta

    2017-01-01

    Research suggests that "healthy" food choices such as eating fruits and vegetables have not only physical but also mental health benefits and might be a long-term investment in future well-being. This view contrasts with the belief that high-caloric foods taste better, make us happy, and alleviate a negative mood. To provide a more comprehensive assessment of food choice and well-being, we investigated in-the-moment eating happiness by assessing complete, real life dietary behaviour across ei...

  15. Toward Virtual Campuses: Collaborative Virtual Labs & Personalized Learning Services in a Real-Life Context

    OpenAIRE

    Tsekeridou, Sofia; Tiropanis, Thanassis; Christou, Ioannis; Vakilzadeh, Haleh

    2008-01-01

    Virtual campuses are gradually becoming a reality with the advances in e-learning and Web technologies, distributed systems and broadband communication, as well as the emerging needs of remote Universities for collaboration on offering common programs. The advances in grid-based distributed infrastructures have further significantly contributed to this fact providing optimized and real-time system performance and support for virtual communities even under synchronous distributed multi-user us...

  16. Text World Theory and real world readers: From literature to life in a Belfast prison.

    Science.gov (United States)

    Canning, Patricia

    2017-05-01

    Cognitive stylistics offers a range of frameworks for understanding (amongst other things) what producers of literary texts 'do' with language and how they 'do' it. Less prevalent, however, is an understanding of the ways in which these same frameworks offer insights into what readers 'do' (and how they 'do' it). Text World Theory (Werth, 1999; Gavins, 2007; Whiteley, 2011) has proved useful for understanding how and why readers construct mental representations engendered by the act of reading. However, research on readers' responses to literature has largely focused on an 'idealised' reader or an 'experimental' subject-reader often derived from within the academy and conducted using contrived or amended literary fiction. Moreover, the format of traditional book groups (participants read texts privately and discuss them at a later date) as well as online community forums such as Goodreads, means that such studies derive data from post-hoc, rather than real-time textual encounters and discussions. The current study is the first of its kind in analysing real-time reading contexts with real readers during a researcher-led literary project ('read.live.learn') in Northern Ireland's only female prison. In doing so, the study is unique in addressing experimental and post hoc bias. Using Text World Theory, the paper considers the personal and social impact of reader engagement in the talk of the participants. As such, it has three interrelated aims: to argue for the social and personal benefits of reading stylistically rich literature in real-time reading groups; to demonstrate the efficacy of stylistics for understanding how those benefits come about, and to demonstrate the inter-disciplinary value of stylistics, particularly its potential for traversing traditional research parameters.

  17. Autonomous social gaze model for an interactive virtual character in real-life settings

    OpenAIRE

    Yumak, Zerrin; van den Brink, Bram; Egges, Arjan

    2018-01-01

    This paper presents a gaze behavior model for an interactive virtual character situated in the real world. We are interested in estimating which user has an intention to interact, in other words which user is engaged with the virtual character. The model takes into account behavioral cues such as proximity, velocity, posture and sound, estimates an engagement score and drives the gaze behavior of the virtual character. Initially, we assign equal weights to these fea...

  18. Rehabilitation of Executive Functions in a Real-Life Setting: Goal Management Training Applied to a Person with Schizophrenia

    Directory of Open Access Journals (Sweden)

    M.-N. Levaux

    2012-01-01

    Full Text Available The aim was to assess the efficacy of a modified version of Goal Management Training (GMT in a person with schizophrenia who had difficulties in attaining the final goal for new and multitasking daily-life situations. GMT is designed to improve abilities in establishing goal-directed plans and carrying them out effectively. Beneficial effects of GMT were measured for several clinical questionnaires, laboratory tasks, and three real-life situations: meal preparation (trained, familiar; washing (nontrained, familiar; meeting preparation (nontrained, unfamiliar. The results revealed improvement in planning and on trained laboratory and meal preparation tasks and a generalization of GMT effects on nontrained laboratory and everyday tasks. Self-esteem also improved. Finally, a two-year followup indicated the durability of the beneficial effects.

  19. Impact of chronic urticaria on quality of life and work in Japan: Results of a real-world study.

    Science.gov (United States)

    Itakura, Asako; Tani, Yumiko; Kaneko, Naoko; Hide, Michihiro

    2018-06-13

    Little attention has been given to the burden of chronic urticaria (CU) in Japan compared with other skin diseases, such as atopic dermatitis (AD) and psoriasis. The primary objective of the RELEASE study was to evaluate the real-life quality-of-life impairment in CU patients in Japan. Data were collected from 1443 urticaria, 1668 AD and 435 psoriatic patients; 552 urticaria patients who presented urticaria symptoms for over 6 weeks were defined as CU. The mean Dermatology Life Quality Index (DLQI) total score was 4.8, 6.1 and 4.8 in CU, AD and psoriatic patients, respectively. Disease control of urticaria evaluated by the Urticaria Control Test (UCT) and DLQI exhibited a strong correlation with a Spearman's rank correlation coefficient of -0.7158. CU and AD patients had relatively higher scores in all Work Productivity and Activity Impairment - General Health subscales except for absenteeism. At the time of the survey, approximately 64% of CU patients reported UCT scores of <12 and demonstrated higher work productivity loss and activity impairment versus patients with UCT scores of ≥12. Patients with lower UCT scores also displayed a higher percentage of dissatisfaction with their health state and the treatment they received. Approximately 85% of patients with CU had visited dermatology clinics, and less than 20% had visited hospital, indicating existence of a highly burdened population outside specialized centers. These results highlight the unmet medical needs of CU patients, suggesting the need to increase awareness of CU burden among both physicians and patients and to pursue improved real-life patient care. © 2018 Novartis K.K. The Journal of Dermatology published by John Wiley & Sons Australia, Ltd on behalf of Japanese Dermatological Association.

  20. The study of key issues about integration of GNSS and strong-motion records for real-time earthquake monitoring

    Science.gov (United States)

    Tu, Rui; Zhang, Pengfei; Zhang, Rui; Liu, Jinhai

    2016-08-01

    This paper has studied the key issues about integration of GNSS and strong-motion records for real-time earthquake monitoring. The validations show that the consistence of the coordinate system must be considered firstly to exclude the system bias between GNSS and strong-motion. The GNSS sampling rate is suggested about 1-5 Hz, and we should give the strong-motion's baseline shift with a larger dynamic noise as its variation is very swift. The initialization time of solving the baseline shift is less than one minute, and ambiguity resolution strategy is not greatly improved the solution. The data quality is very important for the solution, we advised to use multi-frequency and multi-system observations. These ideas give an important guide for real-time earthquake monitoring and early warning by the tight integration of GNSS and strong-motion records.

  1. A GIS-driven integrated real-time surveillance pilot system for national West Nile virus dead bird surveillance in Canada

    Directory of Open Access Journals (Sweden)

    Aramini Jeff

    2006-04-01

    Full Text Available Abstract Background An extensive West Nile virus surveillance program of dead birds, mosquitoes, horses, and human infection has been launched as a result of West Nile virus first being reported in Canada in 2001. Some desktop and web GIS have been applied to West Nile virus dead bird surveillance. There have been urgent needs for a comprehensive GIS services and real-time surveillance. Results A pilot system was developed to integrate real-time surveillance, real-time GIS, and Open GIS technology in order to enhance West Nile virus dead bird surveillance in Canada. Driven and linked by the newly developed real-time web GIS technology, this integrated real-time surveillance system includes conventional real-time web-based surveillance components, integrated real-time GIS components, and integrated Open GIS components. The pilot system identified the major GIS functions and capacities that may be important to public health surveillance. The six web GIS clients provide a wide range of GIS tools for public health surveillance. The pilot system has been serving Canadian national West Nile virus dead bird surveillance since 2005 and is adaptable to serve other disease surveillance. Conclusion This pilot system has streamlined, enriched and enhanced national West Nile virus dead bird surveillance in Canada, improved productivity, and reduced operation cost. Its real-time GIS technology, static map technology, WMS integration, and its integration with non-GIS real-time surveillance system made this pilot system unique in surveillance and public health GIS.

  2. Computational Chemistry Laboratory: Calculating the Energy Content of Food Applied to a Real-Life Problem

    Science.gov (United States)

    Barbiric, Dora; Tribe, Lorena; Soriano, Rosario

    2015-01-01

    In this laboratory, students calculated the nutritional value of common foods to assess the energy content needed to answer an everyday life application; for example, how many kilometers can an average person run with the energy provided by 100 g (3.5 oz) of beef? The optimized geometries and the formation enthalpies of the nutritional components…

  3. Life cycle assessment of biofuels from an integrated Brazilian algae-sugarcane biorefinery

    International Nuclear Information System (INIS)

    Souza, Simone P.; Gopal, Anand R.; Seabra, Joaquim E.A.

    2015-01-01

    Sugarcane ethanol biorefineries in Brazil produce carbon dioxide, electricity and heat as byproducts. These are essential inputs for algae biodiesel production. In this paper, we assessed ethanol's life cycle greenhouse gas emissions and fossil energy use produced in an integrated sugarcane and algae biorefinery where biodiesel replaces petroleum diesel for all agricultural operations. Carbon dioxide from cane juice fermentation is used as the carbon source for algae cultivation, and sugarcane bagasse is the sole source of energy for the entire facility. Glycerin produced from the biodiesel plant is consumed by algae during the mixotrophic growth phase. We assessed the uncertainties through a detailed Monte-Carlo analysis. We found that this integrated system can improve both the life cycle greenhouse gas emissions and the fossil energy use of sugarcane ethanol by around 10% and 50%, respectively, compared to a traditional Brazilian sugarcane ethanol distillery. - Highlights: • A high diesel consumption is associated to the ethanol sugarcane life-cycle. • Sugarcane industry can provide sources of carbon and energy for the algae growing. • The sugarcane-algae integration can improve the ethanol life-cycle performance. • This integration is a promising pathway for the deployment of algae biodiesel. • There are still significant techno-economic barriers associated with algae biodiesel

  4. Organisational Learning and the Organisational Life Cycle: The Differential Aspects of an Integrated Relationship in SMEs

    Science.gov (United States)

    Tam, Steven; Gray, David E.

    2016-01-01

    Purpose: The purpose of this study is to relate the practice of organisational learning in small- and medium-sized enterprises (SMEs) to the organisational life cycle (OLC), contextualising the differential aspects of an integrated relationship between them. Design/methodology/approach: It is a mixed-method study with two consecutive phases. In…

  5. Organizational Leadership and Work-Life Integration: Insights from Three Generations of Men

    Science.gov (United States)

    Smith, Deborah N.; Roebuck, Deborah; Elhaddaoui, Terri

    2016-01-01

    The literature has traditionally portrayed work-life balance as a women's issue. However, working men, specifically those classified as Generation X and Generation Y, are starting to speak up and share that they too are struggling with integrating all aspects of their lives. Workers, as well as organizations can benefit when employees have a…

  6. An MILP approach to shelf life integrated planning and scheduling in scalded sausage production

    DEFF Research Database (Denmark)

    Günther, H.O.; van Beek, P.; Grunow, Martin

    2006-01-01

    in which shelf life aspects are integrated into operational production planning and scheduling functions. Specifically we make use of so-called Mixed Integer Linear Programming (MILP) models. Our research is based on an industrial case study of yogurt production. Relying on the principle of block planning...

  7. Integration Processes of a Romanian Group in a Huelva Village through Family Life Stories

    Science.gov (United States)

    Díaz-Reales, Antonia-María; Aguaded-Gómez, Ignacio

    2015-01-01

    This paper examines the integration of Romanian immigrants in Lucena del Puerto (Huelva, Spain) through the life stories of two families of Romanian origin. The experiences of the groups presented in this study were analyzed. Both families were in the town for work, to grow and harvest strawberries. We observed a contrast between idealistic views…

  8. Integration of ICT in everyday life - exploration of transition processes in an environmental perspective

    DEFF Research Database (Denmark)

    Røpke, Inge

    2009-01-01

    Presently, one of the fastest growing fields of consumption is the use of information and communication technologies (ICT). The integration of ICT in social practices is part of wide-ranging transition processes constructing new ‘normal standards’ in everyday life, and these changes have large...

  9. Emotion and the affective turn: Towards an integration of cognition and affect in real life experience

    Directory of Open Access Journals (Sweden)

    Cornel W. du Toit

    2014-11-01

    Full Text Available Emotion is caused by many factors, some of which are evolutionary, neurological, chemical, environmental, societal, personal and religious. Mostly, however, we are oblivious of the causal factors, many of which may function on a biological level or subconsciously, although the emotional effect is experienced physically and consciously. Emotions change as the trigger mechanisms in the cultural context change. This usually happens unnoticed over long periods. Internet databases have now made it possible to study the use of emotive words; this point is discussed. Of particular interest is the interaction between emotion and reason. Models that reduce emotion to the physical level are scrutinised critically. Reason is not emotionless and emotion is not always irrational. The close interrelationship of emotion and reason often makes it difficult to distinguish accurately between the two. The so-called affective turn takes cognisance of cultural, social, religious and other environmental factors; this broader approach clarifies the importance of affect’s role in rationality. One way of viewing emotion and affect is to look at the accompanying language; here the role of metaphor and narrative is pertinent. The traditional elevation of reason above emotion is examined critically as part of the affective turn that broadens the meaning and scope of emotions. I focus on the role of emotion in religion and factors that influence it, and explore the accent of affect in new spiritualities.

  10. Real-Time Integrated Navigation System for Planetary Exploration (RT-INSPEX), Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — For supporting NASA's efforts in enhancing robotic autonomy and off-loading work from operators and astronauts, American GNC Corporation has developed the "Real-Time...

  11. Integrated deployment architecture for predictive real-time traffic routing incorporating human factors considerations.

    Science.gov (United States)

    2014-05-01

    As Advanced Traveler Information Systems (ATIS) are being more widely accessed by drivers, understanding drivers behavioral responses to real-time travel information through ATIS and its consequential benefits are important to the widespread deplo...

  12. Integrated Chamber Design for the Laser Inertial Fusion Energy (LIFE) Engine

    Energy Technology Data Exchange (ETDEWEB)

    Latkowski, J F; Kramer, K J; Abbott, R P; Morris, K R; DeMuth, J; Divol, L; El-Dasher, B; Lafuente, A; Loosmore, G; Reyes, S; Moses, G A; Fratoni, M; Flowers, D; Aceves, S; Rhodes, M; Kane, J; Scott, H; Kramer, R; Pantano, C; Scullard, C; Sawicki, R; Wilks, S; Mehl, M

    2010-12-07

    The Laser Inertial Fusion Energy (LIFE) concept is being designed to operate as either a pure fusion or hybrid fusion-fission system. A key component of a LIFE engine is the fusion chamber subsystem. The present work details the chamber design for the pure fusion option. The fusion chamber consists of the first wall and blanket. This integrated system must absorb the fusion energy, produce fusion fuel to replace that burned in previous targets, and enable both target and laser beam transport to the ignition point. The chamber system also must mitigate target emissions, including ions, x-rays and neutrons and reset itself to enable operation at 10-15 Hz. Finally, the chamber must offer a high level of availability, which implies both a reasonable lifetime and the ability to rapidly replace damaged components. An integrated LIFE design that meets all of these requirements is described herein.

  13. Integrated Chamber Design for the Laser Inertial Fusion Energy (LIFE) Engine

    International Nuclear Information System (INIS)

    Latkowski, J.F.; Kramer, K.J.; Abbott, R.P.; Morris, K.R.; DeMuth, J.; Divol, L.; El-Dasher, B.; Lafuente, A.; Loosmore, G.; Reyes, S.; Moses, G.A.; Fratoni, M.; Flowers, D.; Aceves, S.; Rhodes, M.; Kane, J.; Scott, H.; Kramer, R.; Pantano, C.; Scullard, C.; Sawicki, R.; Wilks, S.; Mehl, M.

    2010-01-01

    The Laser Inertial Fusion Energy (LIFE) concept is being designed to operate as either a pure fusion or hybrid fusion-fission system. A key component of a LIFE engine is the fusion chamber subsystem. The present work details the chamber design for the pure fusion option. The fusion chamber consists of the first wall and blanket. This integrated system must absorb the fusion energy, produce fusion fuel to replace that burned in previous targets, and enable both target and laser beam transport to the ignition point. The chamber system also must mitigate target emissions, including ions, x-rays and neutrons and reset itself to enable operation at 10-15 Hz. Finally, the chamber must offer a high level of availability, which implies both a reasonable lifetime and the ability to rapidly replace damaged components. An integrated LIFE design that meets all of these requirements is described herein.

  14. Personal attitudes toward time: The relationship between temporal focus, space-time mappings and real life experiences.

    Science.gov (United States)

    Li, Heng; Cao, Yu

    2017-06-01

    What influences how people implicitly associate "past" and "future" with "front" and "back?" Whereas previous research has shown that cultural attitudes toward time play a role in modulating space-time mappings in people's mental models (de la Fuente, Santiago, Román, Dumitrache & Casasanto, 2014), we investigated real life experiences as potential additional influences on these implicit associations. Participants within the same single culture, who are engaged in different intermediate-term educational experiences (Study 1), long-term living experiences (Study 2), and short-term visiting experiences (Study 3), showed their distinct differences in temporal focus, thereby influencing their implicit spatializations of time. Results across samples suggest that personal attitudes toward time related to real life experiences may influence people's space-time mappings. The findings we report on shed further light on the high flexibility of human conceptualization system. While culture may exert an important influence on temporal focus, a person's conceptualization of time may be attributed to a culmination of factors. © 2017 Scandinavian Psychological Associations and John Wiley & Sons Ltd.

  15. Reversal of Dabigatran Using Idarucizumab in a Septic Patient with Impaired Kidney Function in Real-Life Practice

    Directory of Open Access Journals (Sweden)

    Thomas C. Sauter

    2016-01-01

    Full Text Available Background. Immediate reversal of anticoagulation is essential when facing severe bleeding or emergency surgery. Although idarucizumab is approved for the reversal of dabigatran in many countries, clinical experiences are lacking, particularly in special patient-populations such as sepsis and impaired renal function. Case Presentation. We present the case of a 67-year-old male septic patient with a multilocular facial abscess and chronic kidney disease (GFR 36.5 mL/min. Thrombin time (TT and activated partial thromboplastin time (aPTT 15 hours after the last intake of 150 mg dabigatran were both prolonged (>120 sec, resp., 61 sec, as well as unbound dabigatran concentration (119.05 ng/mL. Before immediate emergency surgery dabigatran was antagonised using idarucizumab 2 × 2.5 g. Dabigatran concentration was not detectable 10 min after idarucizumab administration (<30 ng/mL. TT and aPTT time were normalised (16.2 sec, resp., 30.2 sec. Sepsis was controlled after surgery and kidney function remained stable. In the absence of postoperative bleeding, dabigatran was restarted 36 hours after admission. Conclusion. Idarucizumab successfully reversed the effect of dabigatran in real-life practice in a patient with sepsis and renal impairment and allowed emergency surgery with normal haemostasis. Efficacy and safety in real-life practice will nevertheless require prospective registries monitoring.

  16. Cybersex addiction: Experienced sexual arousal when watching pornography and not real-life sexual contacts makes the difference.

    Science.gov (United States)

    Laier, Christian; Pawlikowski, Mirko; Pekal, Jaro; Schulte, Frank P; Brand, Matthias

    2013-06-01

    Background and aims Cybersex addiction is discussed controversially, while empirical evidence is widely missing. With respect to its mechanisms of development and maintenance Brand et al. (2011) assume that reinforcement due to cybersex should lead to the development of cue-reactivity and craving explaining recurrent cybersex use in the face of growing but neglected negative consequences. To support this hypothesis, two experimental studies were conducted. Methods In a cue-reactivity paradigm 100 pornographic cues were presented to participants and indicators of sexual arousal and craving were assessed. The first study aimed at identifying predictors of cybersex addiction in a freely recruited sample of 171 heterosexual males. The aim of the second study was to verify the findings of the first study by comparing healthy (n = 25) and problematic (n = 25) cybersex users. Results The results show that indicators of sexual arousal and craving to Internet pornographic cues predicted tendencies towards cybersex addiction in the first study. Moreover, it was shown that problematic cybersex users report greater sexual arousal and craving reactions resulting from pornographic cue presentation. In both studies, the number and subjective quality of real-life sexual contacts were not associated to cybersex addiction. Discussion The results support the gratification hypothesis, which assumes reinforcement, learning mechanisms, and craving to be relevant processes in the development and maintenance of cybersex addiction. Poor or unsatisfying sexual real-life contacts cannot sufficiently explain cybersex addiction. Conclusions Positive reinforcement in terms of gratification plays a major role in cybersex addiction.

  17. The Italian compassionate use of sofosbuvir in HCV patients waitlisted for liver transplantation: A national real-life experience.

    Science.gov (United States)

    Martini, Silvia; Donato, Maria Francesca; Mazzarelli, Chiara; Rendina, Maria; Visco-Comandini, Ubaldo; Filì, Daniela; Gianstefani, Alice; Fagiuoli, Stefano; Melazzini, Mario; Montilla, Simona; Pani, Luca; Petraglia, Sandra; Russo, Pierluigi; Trotta, Maria Paola; Carrai, Paola; Caraceni, Paolo

    2018-04-01

    This study aimed to assess the real-life clinical and virological outcomes of HCV waitlisted patients for liver transplantation (LT) who received sofosbuvir/ribavirin (SOF/R) within the Italian compassionate use program. Clinical and virological data were collected in 224 patients with decompensated cirrhosis and/or hepatocellular carcinoma (HCC) receiving daily SOF/R until LT or up a maximum of 48 weeks. Of 100 transplanted patients, 51 were HCV-RNA negative for >4 weeks before LT (SVR12: 88%) and 49 negative for <4 weeks or still viraemic at transplant: 34 patients continued treatment after LT (bridging therapy) (SVR12: 88%), while 15 stopped treatment (SVR12: 53%). 98 patients completed SOF/R without LT (SVR12: 73%). In patients with advanced decompensated cirrhosis (basal MELD ≥15 and/or C-P ≥B8), a marked improvement of the scores occurred in about 50% of cases and almost 20% of decompensated patients without HCC reached a condition suitable for inactivation and delisting. These real-life data indicate that in waitlisted patients: (i) bridging antiviral therapy can be an option for patients still viraemic or negative <4 weeks at LT; and (ii) clinical improvement to a condition suitable for delisting can occur even in patients with advanced decompensated cirrhosis. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  18. Linking the microscopic view of chemistry to real-life experiences: Intertextuality in a high-school science classroom

    Science.gov (United States)

    Wu, Hsin-Kai

    2003-11-01

    Chemistry learning involves establishing conceptual relationships among macroscopic, microscopic, and symbolic representations. Employing the notion of intertextuality to conceptualize these relationships, this study investigates how class members interactionally construct meanings of chemical representations by connecting them to real-life experiences and how the teachers' content knowledge shapes their ways to coconstruct intertextual links with students. Multiple sources of data were collected over 7 weeks with a participation of 25 eleventh graders, an experienced teacher, and a student teacher. An examination of classroom discourse shows that the intertextual links between the microscopic view of chemistry and students' real-life experiences could be initiated by students and instigated by the teachers. The teachers applied several discursive strategies to scaffold students building meaningful links based on their prior knowledge and experiences. Additionally, the experienced teacher with stronger content knowledge tended to present links in both dialogic and monologic discourses. Yet, the relatively limited content knowledge did not necessarily constrain the student teacher's interactions with students. The findings of this study provide a backdrop for further research to explore how chemistry is learned and taught in a class through the social constructivist lens.

  19. The correlation between pedestrian injury severity in real-life crashes and Euro NCAP pedestrian test results.

    Science.gov (United States)

    Strandroth, Johan; Rizzi, Matteo; Sternlund, Simon; Lie, Anders; Tingvall, Claes

    2011-12-01

    The aim of the present study was to estimate the correlation between Euro NCAP pedestrian rating scores and injury outcome in real-life car-to-pedestrian crashes, with special focus on long-term disability. Another aim was to determine whether brake assist (BA) systems affect the injury outcome in real-life car-to-pedestrian crashes and to estimate the combined effects in injury reduction of a high Euro NCAP ranking score and BA. In the current study, the Euro NCAP pedestrian scoring was compared with the real-life outcome in pedestrian crashes that occurred in Sweden during 2003 to 2010. The real-life crash data were obtained from the data acquisition system Swedish Traffic Accident Data Acquisition (STRADA), which combines police records and hospital admission data. The medical data consisted of International Classification of Diseases (ICD) diagnoses and Abbreviated Injury Scale (AIS) scoring. In all, approximately 500 pedestrians submitted to hospital were included in the study. Each car model was coded according to Euro NCAP pedestrian scores. In addition, the presence or absence of BA was coded for each car involved. Cars were grouped according to their scoring. Injury outcomes were analyzed with AIS and, at the victim level, with permanent medical impairment. This was done by translating the injury scores for each individual to the risk of serious consequences (RSC) at 1, 5, and 10 percent risk of disability level. This indicates the total risk of a medical disability for each victim, given the severity and location of injuries. The mean RSC (mRSC) was then calculated for each car group and t-tests were conducted to falsify the null hypothesis at p ≤ .05 that the mRSC within the groups was equal. The results showed a significant reduction of injury severity for cars with better pedestrian scoring, although cars with a high score could not be studied due to lack of cases. The reduction in RSC for medium-performing cars in comparison with low-performing cars

  20. Reconstruction of 3d video from 2d real-life sequences

    Directory of Open Access Journals (Sweden)

    Eduardo Ramos Diaz

    2010-01-01

    Full Text Available En este artículo, se propone un método novedoso que permite generar secuencias de video en 3D usando secuencias de video reales en 2D. La reconstrucción de la secuencia de video en 3D se realiza usando el cálculo del mapa de profundidad y la síntesis de anaglifos. El mapa de profundidad es formado usando la técnica de correspondencia estéreo basada en la minimización de la energía de error global a partir de funciones de suavizado. La construcción del anaglifo es realizada usando la alineación del componente de color interpolándolo con el mapa de profundidad previamente formado. Adicionalmente, se emplea la transformación del mapa de profundidad para reducir el rango dinámico de los valores de disparidad, minimizando el efecto fantasma mejorando la preservación de color. Se usaron numerosas secuencias de video a color reales que contienen diferentes tipos de movimientos como traslacional, rotacional, acercamiento, y la combinación de los anteriores, demostrando buen funcionamiento visual de la reconstrucción de secuencias de video en 3D propuesta.

  1. A Real-Time Measurement System for Long-Life Flood Monitoring and Warning Applications

    Directory of Open Access Journals (Sweden)

    Antonio Skarmeta Gómez

    2012-03-01

    Full Text Available A flood warning system incorporates telemetered rainfall and flow/water level data measured at various locations in the catchment area. Real-time accurate data collection is required for this use, and sensor networks improve the system capabilities. However, existing sensor nodes struggle to satisfy the hydrological requirements in terms of autonomy, sensor hardware compatibility, reliability and long-range communication. We describe the design and development of a real-time measurement system for flood monitoring, and its deployment in a flash-flood prone 650 km2 semiarid watershed in Southern Spain. A developed low-power and long-range communication device, so-called DatalogV1, provides automatic data gathering and reliable transmission. DatalogV1 incorporates self-monitoring for adapting measurement schedules for consumption management and to capture events of interest. Two tests are used to assess the success of the development. The results show an autonomous and robust monitoring system for long-term collection of water level data inmany sparse locations during flood events.

  2. Removal of Dissolved Silica using Calcinated Hydrotalcite in Real-life Applications.

    Energy Technology Data Exchange (ETDEWEB)

    Sasan, Koroush [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Brady, Patrick Vane. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Krumhansl, James L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Nenoff, Tina M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Sasan, Koroush [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Sasan, Koroush [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-09-01

    Water shortages are a growing global problem. Reclamation of industrial and municipal wastewater will be necessary in order to mitigate water scarcity. However, many operational challenges, such as silica scaling, prevent large scale water reuse. Previously, our team at Sandia has demonstrated the use of selective ion exchange materials, such as calcinated hydrotalcite (HTC, (Mg 6 Al 2 (OH) 16 (CO 3 )*4H 2 O)), for the low cost removal of silica from synthetic cooling tower water. However, it is not currently know if calcinated HTC has similar capabilities in realistic applications. The purpose of this study was to investigate the ability of calcinated HTC to remove silica from real cooling tower water. This was investigated under both batch and continuous conditions, and in the presence of competing ions. It was determined that calcinated HTC behaved similarly in real and synthetic cooling tower water; the HTC is highly selective for the silica even in the presence of competing cations. Therefore, the data concludes that calcinated HTC is a viable anti-scaling pretreatment for the reuse of industrial wastewaters.

  3. Predicting Smartphone Battery Life based on Comprehensive and Real-time Usage Data

    OpenAIRE

    Li, Huoran; Liu, Xuanzhe; Mei, Qiaozhu

    2018-01-01

    Smartphones and smartphone apps have undergone an explosive growth in the past decade. However, smartphone battery technology hasn't been able to keep pace with the rapid growth of the capacity and the functionality of smartphones and apps. As a result, battery has always been a bottleneck of a user's daily experience of smartphones. An accurate estimation of the remaining battery life could tremendously help the user to schedule their activities and use their smartphones more efficiently. Ex...

  4. Is This Real Life? Is This Just Fantasy?: Realism and Representations in Learning with Technology

    Science.gov (United States)

    Sauter, Megan Patrice

    Students often engage in hands-on activities during science learning; however, financial and practical constraints often limit the availability of these activities. Recent advances in technology have led to increases in the use of simulations and remote labs, which attempt to recreate hands-on science learning via computer. Remote labs and simulations are interesting from a cognitive perspective because they allow for different relations between representations and their referents. Remote labs are unique in that they provide a yoked representation, meaning that the representation of the lab on the computer screen is actually linked to that which it represents: a real scientific device. Simulations merely represent the lab and are not connected to any real scientific devices. However, the type of visual representations used in the lab may modify the effects of the lab technology. The purpose of this dissertation is to examine the relation between representation and technology and its effects of students' psychological experiences using online science labs. Undergraduates participated in two studies that investigated the relation between technology and representation. In the first study, participants performed either a remote lab or a simulation incorporating one of two visual representations, either a static image or a video of the equipment. Although participants in both lab conditions learned, participants in the remote lab condition had more authentic experiences. However, effects were moderated by the realism of the visual representation. Participants who saw a video were more invested and felt the experience was more authentic. In a second study, participants performed a remote lab and either saw the same video as in the first study, an animation, or the video and an animation. Most participants had an authentic experience because both representations evoked strong feelings of presence. However, participants who saw the video were more likely to believe the

  5. Integrated Metrics for Improving the Life Cycle Approach to Assessing Product System Sustainability

    Directory of Open Access Journals (Sweden)

    Wesley Ingwersen

    2014-03-01

    Full Text Available Life cycle approaches are critical for identifying and reducing environmental burdens of products. While these methods can indicate potential environmental impacts of a product, current Life Cycle Assessment (LCA methods fail to integrate the multiple impacts of a system into unified measures of social, economic or environmental performance related to sustainability. Integrated metrics that combine multiple aspects of system performance based on a common scientific or economic principle have proven to be valuable for sustainability evaluation. In this work, we propose methods of adapting four integrated metrics for use with LCAs of product systems: ecological footprint, emergy, green net value added, and Fisher information. These metrics provide information on the full product system in land, energy, monetary equivalents, and as a unitless information index; each bundled with one or more indicators for reporting. When used together and for relative comparison, integrated metrics provide a broader coverage of sustainability aspects from multiple theoretical perspectives that is more likely to illuminate potential issues than individual impact indicators. These integrated metrics are recommended for use in combination with traditional indicators used in LCA. Future work will test and demonstrate the value of using these integrated metrics and combinations to assess product system sustainability.

  6. Physiologically based pharmacokinetic toolkit to evaluate environmental exposures: Applications of the dioxin model to study real life exposures

    Energy Technology Data Exchange (ETDEWEB)

    Emond, Claude, E-mail: claude.emond@biosmc.com [BioSimulation Consulting Inc, Newark, DE (United States); Ruiz, Patricia; Mumtaz, Moiz [Division of Toxicology and Human Health Sciences, Agency for Toxic Substances and Disease Registry, Atlanta, GA (United States)

    2017-01-15

    Chlorinated dibenzo-p-dioxins (CDDs) are a series of mono- to octa-chlorinated homologous chemicals commonly referred to as polychlorinated dioxins. One of the most potent, well-known, and persistent member of this family is 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). As part of translational research to make computerized models accessible to health risk assessors, we present a Berkeley Madonna recoded version of the human physiologically based pharmacokinetic (PBPK) model used by the U.S. Environmental Protection Agency (EPA) in the recent dioxin assessment. This model incorporates CYP1A2 induction, which is an important metabolic vector that drives dioxin distribution in the human body, and it uses a variable elimination half-life that is body burden dependent. To evaluate the model accuracy, the recoded model predictions were compared with those of the original published model. The simulations performed with the recoded model matched well with those of the original model. The recoded model was then applied to available data sets of real life exposure studies. The recoded model can describe acute and chronic exposures and can be useful for interpreting human biomonitoring data as part of an overall dioxin and/or dioxin-like compounds risk assessment. - Highlights: • The best available dioxin PBPK model for interpreting human biomonitoring data is presented. • The original PBPK model was recoded from acslX to the Berkeley Madonna (BM) platform. • Comparisons were made of the accuracy of the recoded model with the original model. • The model is a useful addition to the ATSDR's BM based PBPK toolkit that supports risk assessors. • The application of the model to real-life exposure data sets is illustrated.

  7. Empirical Platform Data Analysis to Investigate how Heat Pumps Operate in Real-Life Conditions

    DEFF Research Database (Denmark)

    Carmo, Carolina; Elmegaard, Brian; Nielsen, M. P.

    2015-01-01

    Heat pumps have been widely acknowledged, by academia and industry, as highly efficient thermal energy technologies, for space heating and domestic hot water production. However, there is a lack of information about real performance in residential single family houses with active participation...... of end-users. In this paper, an analysis based on data from 242 heat pump installations in Denmark gathered over a period up to 4 years (2010 until today) is performed. COP, operating temperatures and socio-demographic data are used as basis for comparing theoretical and actual performance. Six different...... heat pump configurations are considered depending on source (ground or air) and sink (radiators, floor heating and/or combined systems). This unique study intends to point out the benefits and limitations of such technologies in terms of energy efficiency and comfort delivery, as well as investigating...

  8. Implementation Process of 5S for a Company in Real Life - Problems, Solutions, Successes

    Science.gov (United States)

    Czifra, György

    2017-09-01

    Developed in Japan, 5S is a system of organizing workplace for efficiency, effectiveness and safety. Is 5s important? The answer is: "YES", because the implementation is about empowering employees to control their work area and create an environment where they want to work every day. It is a program that only works with grass roots level engagement. With commitment to safety, we are equally committed to 5S to ensure a safe place to work. It enabled us to indicate where waste was occurring and thus improve the work area sustainably. We recognized real problems, found solutions and ultimately we were successful in our endeavors. Throughout different companies, various words of similar meaning are used. No matter what specific words are used to identify the steps in 5S, the purpose remains the same: create a clean, organized and efficient work environment.

  9. Implementation Process of 5S for a Company in Real Life - Problems, Solutions, Successes

    Directory of Open Access Journals (Sweden)

    Czifra György

    2017-09-01

    Full Text Available Developed in Japan, 5S is a system of organizing workplace for efficiency, effectiveness and safety. Is 5s important? The answer is: “YES”, because the implementation is about empowering employees to control their work area and create an environment where they want to work every day. It is a program that only works with grass roots level engagement. With commitment to safety, we are equally committed to 5S to ensure a safe place to work. It enabled us to indicate where waste was occurring and thus improve the work area sustainably. We recognized real problems, found solutions and ultimately we were successful in our endeavors. Throughout different companies, various words of similar meaning are used. No matter what specific words are used to identify the steps in 5S, the purpose remains the same: create a clean, organized and efficient work environment.

  10. An integrated programme after pulmonary rehabilitation in patients with chronic obstructive pulmonary disease: effect on emotional and functional dimensions of quality of life.

    Science.gov (United States)

    Moullec, G; Ninot, G

    2010-02-01

    To assess whether a maintenance integrated health care programme is effective in improving functional and emotional dimensions of quality of life in patients with chronic obstructive pulmonary disease (COPD) after a first pulmonary rehabilitation. Prospective controlled trial. Three rehabilitation centres and three patient self-help associations within a health care network in France. Forty patients with moderate to severe COPD. After a first four-week inpatient pulmonary rehabilitation programme, patients took part in a maintenance integrated health care programme or usual care for 12 months. The primary outcomes were the change in functional and emotional dimensions of quality of life measured by the St George's Respiratory Questionnaire (SGRQ), the brief World Health Organization Quality of Life questionnaire (Brief-WHOQOL) and six specific questions using a 10-cm visual analogue scale. Secondary outcomes were change in exercise tolerance measured by six-minute walking test and cycle exercise. At one year, the maintenance intervention (n = 11) produced improvements in functional and emotional dimensions scores of quality of life and exercise tolerance. Patients in the usual aftercare group (n = 16) exhibited maintenance of functional dimension scores of quality of life, but a clinically relevant decline in emotional scores of quality of life and in six-minute walking distance one year after the pulmonary rehabilitation. Patient self-help association seems to be an innovative and efficient organizational structure to support patients with COPD after pulmonary rehabilitation in real-life settings. A distinction between emotional and functional dimensions of quality of life may improve the design and evaluation of integrated health care programmes in patients with COPD.

  11. Developing a Web-based system by integrating VGI and SDI for real estate management and marketing

    Directory of Open Access Journals (Sweden)

    J. Salajegheh

    2014-10-01

    Full Text Available Property importance of various aspects, especially the impact on various sectors of the economy and the country's macroeconomic is clear. Because of the real, multi-dimensional and heterogeneous nature of housing as a commodity, the lack of an integrated system includes comprehensive information of property, the lack of awareness of some actors in this field about comprehensive information about property and the lack of clear and comprehensive rules and regulations for the trading and pricing, several problems arise for the people involved in this field. In this research implementation of a crowd-sourced Web-based real estate support system is desired. Creating a Spatial Data Infrastructure (SDI in this system for collecting, updating and integrating all official data about property is also desired in this study. In this system a Web2.0 broker and technologies such as Web services and service composition has been used. This work aims to provide comprehensive and diverse information about property from different sources. For this purpose five-level real estate support system architecture is used. PostgreSql DBMS is used to implement the desired system. Geoserver software is also used as map server and reference implementation of OGC (Open Geospatial Consortium standards. And Apache server is used to run web pages and user interfaces. Integration introduced methods and technologies provide a proper environment for various users to use the system and share their information. This goal is only achieved by cooperation between all involved organizations in real estate with implementation their required infrastructures in interoperability Web services format.

  12. Developing a Web-based system by integrating VGI and SDI for real estate management and marketing

    Science.gov (United States)

    Salajegheh, J.; Hakimpour, F.; Esmaeily, A.

    2014-10-01

    Property importance of various aspects, especially the impact on various sectors of the economy and the country's macroeconomic is clear. Because of the real, multi-dimensional and heterogeneous nature of housing as a commodity, the lack of an integrated system includes comprehensive information of property, the lack of awareness of some actors in this field about comprehensive information about property and the lack of clear and comprehensive rules and regulations for the trading and pricing, several problems arise for the people involved in this field. In this research implementation of a crowd-sourced Web-based real estate support system is desired. Creating a Spatial Data Infrastructure (SDI) in this system for collecting, updating and integrating all official data about property is also desired in this study. In this system a Web2.0 broker and technologies such as Web services and service composition has been used. This work aims to provide comprehensive and diverse information about property from different sources. For this purpose five-level real estate support system architecture is used. PostgreSql DBMS is used to implement the desired system. Geoserver software is also used as map server and reference implementation of OGC (Open Geospatial Consortium) standards. And Apache server is used to run web pages and user interfaces. Integration introduced methods and technologies provide a proper environment for various users to use the system and share their information. This goal is only achieved by cooperation between all involved organizations in real estate with implementation their required infrastructures in interoperability Web services format.

  13. [Terminal home care "Ikigai no Yoake--The real aim of our life"--case report].

    Science.gov (United States)

    Funato, T; Funato, H; Kato, A; Matsuoka, Y; Shibuya, R; Usui, Y; Niwa, Y

    1998-12-01

    It is difficult to provide home care especially for terminal cancer patients as their physical conditions deteriorate due to the cancer. It is important to enhance the will of home care providers to make this possible. Although a universal method has been worked out, personal and religious beliefs have made it difficult to create an effective method. We would like to introduce our experience in the paper entitled "Ikigai no Yoake" and subtitled "Influence of scientific study of reincarnation on view of life" by Fumihiko Ida of Fukushima University. It has encouraged home care providers and made it possible to provide home care to terminal patients along with benefits.

  14. Exploring and modelling impacts of third molar experience on quality of life: a real-time qualitative study using Twitter.

    Science.gov (United States)

    Hanna, Kamal; Sambrook, Paul; Armfield, Jason M; Brennan, David S

    2017-10-01

    This study had two objectives: (i) to explore and model domains describing the real-time impact of third molars (TMs) on quality of life (QoL); and (ii) to assess the percentage coverage, in some generic health-related quality of life (HRQoL) and oral health-related quality of life (OHRQoL) instruments, of the TM QoL domains identified in this study. A global cross-sectional sample of tweets containing 'wisdom tooth' over a 1-week period retrieved 3,537 tweets. After random quota sampling, classification and filtering, only 843 tweets were included in the thematic analysis. A TM QoL model was constructed based on the associations of the identified domains. Domains for the selected generic HRQoL and OHRQoL instruments were plotted against the domains identified in the study to calculate the percentage coverage for each. The QoL domains identified were pain (n = 348, 41%), mood (n = 173, 20%), anxiety and fear (n = 54, 7%), enjoying food (n = 41, 4%), coping (n = 37, 4%), daily activities (n = 34, 4%), sleep (n = 24, 2%), social life (n = 19, 2%), physical health (n = 17, 2%), ability to think (n = 9, 1%), self-care (n = 8, 1%) and sporting & recreation (n = 2, <1%). The Assessment Quality of Life instrument (AQoL-8D) covers 87% of the TM QoL domains, while the rest of the HRQoL and OHRQoL instruments cover 33-60%. This study shows how Twitter can be used to obtain real-time QoL data, which might be used to model how TMs impact on QoL. The TM QoL domains identified in the study were generally under-represented among the generic OHRQoL instruments assessed while, the HRQoL AQoL-8D covered most of the TM QoL domains. The QoL domains identified in the study might be used to develop a new OHRQoL measure for TMs. © 2017 FDI World Dental Federation.

  15. Towards real energy economics: Energy policy driven by life-cycle carbon emission

    International Nuclear Information System (INIS)

    Kenny, R.; Law, C.; Pearce, J.M.

    2010-01-01

    Alternative energy technologies (AETs) have emerged as a solution to the challenge of simultaneously meeting rising electricity demand while reducing carbon emissions. However, as all AETs are responsible for some greenhouse gas (GHG) emissions during their construction, carbon emission 'Ponzi Schemes' are currently possible, wherein an AET industry expands so quickly that the GHG emissions prevented by a given technology are negated to fabricate the next wave of AET deployment. In an era where there are physical constraints to the GHG emissions the climate can sustain in the short term this may be unacceptable. To provide quantitative solutions to this problem, this paper introduces the concept of dynamic carbon life-cycle analyses, which generate carbon-neutral growth rates. These conceptual tools become increasingly important as the world transitions to a low-carbon economy by reducing fossil fuel combustion. In choosing this method of evaluation it was possible to focus uniquely on reducing carbon emissions to the recommended levels by outlining the most carbon-effective approach to climate change mitigation. The results of using dynamic life-cycle analysis provide policy makers with standardized information that will drive the optimization of electricity generation for effective climate change mitigation.

  16. An integrative review of health-related quality of life in patients with critical limb ischaemia.

    Science.gov (United States)

    Monaro, Susan; West, Sandra; Gullick, Janice

    2017-10-01

    To examine the domains and the domain-specific characteristics within a peripheral arterial disease health-related quality of life framework for their usefulness in defining critical limb ischaemia health-related quality of life. Critical Limb Ischaemia presents a highly individualised set of personal and health circumstances. Treatment options include conservative management, revascularisation or amputation. However, the links between treatment decisions and quality of life require further investigation. The framework for this integrative review was the peripheral arterial disease-specific health-related quality of life domains identified by Treat-Jacobson et al. The literature expanded and refined Treat-Jacobson's framework by modifying the characteristics to better describe health-related quality of life in critical limb ischaemia. Given that critical limb ischaemia is a highly individualised situation with powerful health-related quality of life implications, further research focusing on patient and family-centred decision-making relating to therapeutic options and advanced care planning is required. A critical limb ischaemia-specific, health-related quality of life tool is required to capture both the unique characteristics of this disorder, and the outcomes for active or conservative care among this complex group of patients. © 2016 John Wiley & Sons Ltd.

  17. The Tsimane Health and Life History Project: Integrating anthropology and biomedicine.

    Science.gov (United States)

    Gurven, Michael; Stieglitz, Jonathan; Trumble, Benjamin; Blackwell, Aaron D; Beheim, Bret; Davis, Helen; Hooper, Paul; Kaplan, Hillard

    2017-04-01

    The Tsimane Health and Life History Project, an integrated bio-behavioral study of the human life course, is designed to test competing hypotheses of human life-history evolution. One aim is to understand the bidirectional connections between life history and social behavior in a high-fertility, kin-based context lacking amenities of modern urban life (e.g. sanitation, banks, electricity). Another aim is to understand how a high pathogen burden influences health and well-being during development and adulthood. A third aim addresses how modernization shapes human life histories and sociality. Here we outline the project's goals, history, and main findings since its inception in 2002. We reflect on the implications of current findings and highlight the need for more coordinated ethnographic and biomedical study of contemporary nonindustrial populations to address broad questions that can situate evolutionary anthropology in a key position within the social and life sciences. © 2017 The Authors Evolutionary Anthropology: Issues, News, and Reviews Published by Wiley Periodicals, Inc.

  18. Conceptual Integration of Arithmetic Operations with Real-World Knowledge: Evidence from Event-Related Potentials

    Science.gov (United States)

    Guthormsen, Amy M.; Fisher, Kristie J.; Bassok, Miriam; Osterhout, Lee; DeWolf, Melissa; Holyoak, Keith J.

    2016-01-01

    Research on language processing has shown that the disruption of conceptual integration gives rise to specific patterns of event-related brain potentials (ERPs)--N400 and P600 effects. Here, we report similar ERP effects when adults performed cross-domain conceptual integration of analogous semantic and mathematical relations. In a problem-solving…

  19. Integration of Social Aspects in Decision Support, Based on Life Cycle Thinking

    Directory of Open Access Journals (Sweden)

    Pere Fullana-i-Palmer

    2011-03-01

    Full Text Available Recently increasing attention has been paid to complementing environmental Life Cycle Assessment (LCA with social aspects. The paper discusses the selection of social impacts and indicators from existing frameworks like Social Life Cycle Assessment (SLCA and Social Impact Assessment (SIA. Two ongoing case studies, addressing sustainability assessment within decision support, were considered: (1 Integrated Water Resources Management (IWRM in Indonesia; and (2 Integrated Packaging Waste Management in Spain and Portugal (FENIX. The focus was put on social impacts occurring due to decisions within these systems, such as choice of technologies, practices or suppliers. Thus, decision makers—here understood as intended users of the studies’ results—are not consumers that buy (or do not buy a product, such as in recent SLCA case-studies, but mainly institutions that decide about the design of the water or packaging waste management system. Therefore, in the FENIX project, a list of social impacts identified from literature was sent to the intended users to be ranked according to their priorities. Finally, the paper discusses to what extent the entire life cycle is reflected in SLCA impact categories and indicators, and explains how both life-cycle and on-site-related social impacts were chosen to be assessed. However, not all indicators in the two projects will assess all stages of the life cycle, because of their varying relevance in the different stages, data availability and practical interest of decision makers.

  20. Real-life treatment of metastatic colorectal cancer with regorafenib: a single-centre review.

    Science.gov (United States)

    Gotfrit, J; Vickers, M; Sud, S; Asmis, T; Cripps, C; Goel, R; Hsu, T; Jonker, D; Goodwin, R

    2017-08-01

    Various tyrosine kinase signalling pathways affect the development and progression of colorectal cancer (crc). In clinical trials, regorafenib has been associated with a survival benefit in metastatic crc (mcrc). We assessed the safety and efficacy of regorafenib in real-world patients. In a retrospective review of patients with mcrc treated with regorafenib at our institution from 2013 to 2015, patient demographics, treatment, and survival data were collected. Progression-free survival (pfs) and overall survival (os) were estimated using the Kaplan-Meier method. In total, 48 patients were offered regorafenib, and 35 (73%) started treatment. Of the patients who started regorafenib, 57% were men. Median age in the cohort was 61 years, and all patients had a performance status in the range 0-2. Time from diagnosis of mcrc to regorafenib treatment was more than 18 months in 71% of patients. Starting dose was 160 mg in 54% of the patients, 120 mg in 40%, and 80 mg in 6%. Dose reductions occurred in 34% of the patients, and interruptions, in 29%. Best response was progressive disease (60%) and stable disease (17%); response in the rest of the patients was unknown. The most common adverse events on regorafenib (any grade) were fatigue (57%), hyperbilirubinemia (43%), thrombocytopenia (37%), anorexia (31%), and hypertension (31%). The most common grade 3 or 4 adverse events were fatigue (29%), hypophosphatemia (17%), weight loss (11%), and hyperbilirubinemia (9%). Common reasons for discontinuing regorafenib included progressive disease (51%) and toxicity (26%). In patients treated with regorafenib, pfs was 2.4 months (95% confidence interval: 1.8 to 3.3 months) and os was 5.6 months (95% confidence interval: 3.7 to 8.9 months). No factors were associated with survival in univariate or multivariate analysis. In a real-world setting, regorafenib is associated with survival similar to that reported in the randomized controlled trials, but at the expense of toxicity leading

  1. Integration of NASA-Developed Lifing Technology for PM Alloys into DARWIN (registered trademark)

    Science.gov (United States)

    McClung, R. Craig; Enright, Michael P.; Liang, Wuwei

    2011-01-01

    In recent years, Southwest Research Institute (SwRI) and NASA Glenn Research Center (GRC) have worked independently on the development of probabilistic life prediction methods for materials used in gas turbine engine rotors. The two organizations have addressed different but complementary technical challenges. This report summarizes a brief investigation into the current status of the relevant technology at SwRI and GRC with a view towards a future integration of methods and models developed by GRC for probabilistic lifing of powder metallurgy (P/M) nickel turbine rotor alloys into the DARWIN (Darwin Corporation) software developed by SwRI.

  2. Mixing a Career in the Geosciences with Real Family Life: One Woman's Perspective

    Science.gov (United States)

    Johnson, R. M.

    2001-12-01

    A career in the geosciences can offer many exciting opportunities for discovery, challenges, and rewards. The question is, can a successful career in our field be mixed with a full family life including spouse, children, and other family responsibilities? As a mother of three young children, married to a geoscientist, I have worked for over a decade to find a balance between a full time job and family responsibilities. This presentation will highlight some of the career management techniques that can be used to attempt to balance these competing priorities for dual career couples. Additionally, structural barriers that hamper opportunities for female geoscientists to progress will be discussed. Finally, the positive effects of the development of family friendly policies within professional societies and at places of employment will be highlighted.

  3. The effect of a low-speed automatic brake system estimated from real life data.

    Science.gov (United States)

    Isaksson-Hellman, Irene; Lindman, Magdalena

    2012-01-01

    A substantial part of all traffic accidents involving passenger cars are rear-end collisions and most of them occur at low speed. Auto Brake is a feature that has been launched in several passenger car models during the last few years. City Safety is a technology designed to help the driver mitigate, and in certain situations avoid, rear-end collisions at low speed by automatically braking the vehicle.Studies have been presented that predict promising benefits from these kinds of systems, but few attempts have been made to show the actual effect of Auto Brake. In this study, the effect of City Safety, a standard feature on the Volvo XC60 model, is calculated based on insurance claims data from cars in real traffic crashes in Sweden. The estimated claim frequency of rear-end frontal collisions measured in claims per 1,000 insured vehicle years was 23% lower for the City Safety equipped XC60 model than for other Volvo models without the system.

  4. Mapping dynamic social networks in real life using participants' own smartphones

    Directory of Open Access Journals (Sweden)

    Tjeerd W. Boonstra

    2015-11-01

    Full Text Available Interpersonal relationships are vital for our daily functioning and wellbeing. Social networks may form the primary means by which environmental influences determine individual traits. Several studies have shown the influence of social networks on decision-making, behaviors and wellbeing. Smartphones have great potential for measuring social networks in a real world setting. Here we tested the feasibility of using people's own smartphones as a data collection platform for face-to-face interactions. We developed an application for iOS and Android to collect Bluetooth data and acquired one week of data from 14 participants in our organization. The Bluetooth scanning statistics were used to quantify the time-resolved connection strength between participants and define the weights of a dynamic social network. We used network metrics to quantify changes in network topology over time and non-negative matrix factorization to identify cliques or subgroups that reoccurred during the week. The scanning rate varied considerably between smartphones running Android and iOS and egocentric networks metrics were correlated with the scanning rate. The time courses of two identified subgroups matched with two meetings that took place that week. These findings demonstrate the feasibility of using participants' own smartphones to map social network, whilst identifying current limitations of using generic smartphones. The bias introduced by variations in scanning rate and missing data is an important limitation that needs to be addressed in future studies.

  5. Bioaerosol exposure during refuse collection: results of field studies in the real-life situation.

    Science.gov (United States)

    Neumann, H D; Balfanz, J; Becker, G; Lohmeyer, M; Mathys, W; Raulf-Heimsoth, M

    2002-07-03

    To determine the bioaerosol exposure of refuse collectors, field measurements were performed under real working conditions within the framework of a research project. Influencing variables such as different types of refuse, community structure, collection interval and season were taken into account. Overall, 1612 samples were taken in towns of Westfalia, Germany. With workplace levels on a scale of 10(3) to less than 10(4) CFU/m3 for the loader, the results show a surprisingly low total fungi concentration in comparison with earlier studies. Total bacteria concentrations, in contrast, were largely on a scale of 10(4) CFU/m3, with 10(5) CFU/m3 being registered sporadically, especially in apartment-block districts. Endotoxin levels were high especially in the summer months, occasionally reaching values of more than 50 EU/m3, whereas they were normally below 10 EU/m3 in autumn and winter. Inside the cab, the exposure level for the entire spectrum was at least one power of ten lower. The factors believed to account primarily for the low total fungi concentration were workplace hygiene, the prevailing 1-week collection interval, and the low in-process exposure time resulting from the effective deployment of automatic lifting devices. In contrast, the type of refuse was not found to have a significant influence.

  6. Solving Algebraic Riccati Equation Real Time for Integrated Vehicle Dynamics Control

    NARCIS (Netherlands)

    Kunnappillil Madhusudhanan, A; Corno, M.; Bonsen, B.; Holweg, E.

    2012-01-01

    In this paper we present a comparison study of different computational methods to implement State Dependent Riccati Equation (SDRE) based control in real time for a vehicle dynamics control application. Vehicles are mechatronic systems with nonlinear dynamics. One of the promising nonlinear control

  7. Integrating Real-Time Antecedent Rubrics via Blackboard™ into a Community College General Psychology Class

    Science.gov (United States)

    Goomas, David

    2015-01-01

    Numerous studies have reported on the innovative and effective delivery of online course content by community colleges, but not much has been done on how learning management systems (LMS) can deliver real-time (immediate data delivery) antecedents that inform students of performance requirements. This pilot study used Blackboard's™ interactive…

  8. Protein Analysis Using Real-Time PCR Instrumentation: Incorporation in an Integrated, Inquiry-Based Project

    Science.gov (United States)

    Southard, Jonathan N.

    2014-01-01

    Instrumentation for real-time PCR is used primarily for amplification and quantitation of nucleic acids. The capability to measure fluorescence while controlling temperature in multiple samples can also be applied to the analysis of proteins. Conformational stability and changes in stability due to ligand binding are easily assessed. Protein…

  9. Integrated payload and mission planning, phase 3. Volume 3: Ground real-time mission operations

    Science.gov (United States)

    White, W. J.

    1977-01-01

    The payloads tentatively planned to fly on the first two Spacelab missions were analyzed to examine the cost relationships of providing mission operations support from onboard vs the ground-based Payload Operations Control Center (POCC). The quantitative results indicate that use of a POCC, with data processing capability, to support real-time mission operations is the most cost effective case.

  10. Equality of some integrals from real and imaginary parts of a scattering amplitude

    International Nuclear Information System (INIS)

    Vernov, Yu.S.; Konovalov, A.V.; Mnatsakanova, M.N.

    1984-01-01

    Relation between the behaviour of real and imaginary parts of a forward elastic scattering amplitude is investigated on the basis of analyticity and crossing symmetry. Possibility for the generalization of this equality also for symmetric amplitude resulted from dispersion relations was considered. It is noted that the investigation performed is true for any function complying with the dispersion relation, for example, for polarization operator

  11. Treatment satisfaction of patients undergoing ranibizumab therapy for neovascular age-related macular degeneration in a real-life setting

    Directory of Open Access Journals (Sweden)

    Gohil R

    2016-05-01

    Full Text Available Rishma Gohil,1,2 Roxanne Crosby-Nwaobi,1,2 Angus Forbes,2 Ben J Burton,3 Philip Hykin,1 Sobha Sivaprasad1,4 1National Institute for Health Research Moorfields Biomedical Research Centre, London, 2Diabetes Nursing, King’s College London, London, 3Ophthalmology Department, James Paget University Hospital, Great Yarmouth, 4Laser and Retinal Research Unit, King’s College Hospital, London, UK Context: Treatment satisfaction with a loading phase of monthly injections for 3 months followed by a pro-re-nata regimen of ranibizumab in neovascular age-related macular degeneration (nAMD remains unclear.Aims: The aim was to evaluate the treatment satisfaction of persons with nAMD treated with ranibizumab in a real-life setting.Settings and design: A cross-sectional study was conducted across three eye clinics within the National Health Service in the UK, where treatment is provided free at point of contact.Materials and methods: A total of 250 patients were selected randomly for the study. Treatment satisfaction was assessed using the Macular Treatment Satisfaction Questionnaire. Data were collected on satisfaction of the service provided (Client Service Questionnaire-8 and the patients’ demographic and quality of life and treatment history. Factors governing treatment questionnaire were determined.Results: The most important factors that determined the satisfaction were the service provided at the clinic (Client Service Questionnaire-8, health-related quality of life (EQ-5D-3L, and duration of AMD. Visual acuity changes were rated as less important than one would have expected.Conclusion: The study result suggested that treatment satisfaction for nAMD was governed by the perception of being reviewed and injected regularly over a long period of time than the actual change in visual acuity from the treatment. Keyword: macular treatment satisfaction questionnaire, patient related outcome measure, treatment history, quality of life 

  12. The Performance Analysis of a Real-Time Integrated INS/GPS Vehicle Navigation System with Abnormal GPS Measurement Elimination

    Directory of Open Access Journals (Sweden)

    Jhen-Kai Liao

    2013-08-01

    Full Text Available The integration of an Inertial Navigation System (INS and the Global Positioning System (GPS is common in mobile mapping and navigation applications to seamlessly determine the position, velocity, and orientation of the mobile platform. In most INS/GPS integrated architectures, the GPS is considered to be an accurate reference with which to correct for the systematic errors of the inertial sensors, which are composed of biases, scale factors and drift. However, the GPS receiver may produce abnormal pseudo-range errors mainly caused by ionospheric delay, tropospheric delay and the multipath effect. These errors degrade the overall position accuracy of an integrated system that uses conventional INS/GPS integration strategies such as loosely coupled (LC and tightly coupled (TC schemes. Conventional tightly coupled INS/GPS integration schemes apply the Klobuchar model and the Hopfield model to reduce pseudo-range delays caused by ionospheric delay and tropospheric delay, respectively, but do not address the multipath problem. However, the multipath effect (from reflected GPS signals affects the position error far more significantly in a consumer-grade GPS receiver than in an expensive, geodetic-grade GPS receiver. To avoid this problem, a new integrated INS/GPS architecture is proposed. The proposed method is described and applied in a real-time integrated system with two integration strategies, namely, loosely coupled and tightly coupled schemes, respectively. To verify the effectiveness of the proposed method, field tests with various scenarios are conducted and the results are compared with a reliable reference system.

  13. Machine remaining useful life prediction: An integrated adaptive neuro-fuzzy and high-order particle filtering approach

    Science.gov (United States)

    Chen, Chaochao; Vachtsevanos, George; Orchard, Marcos E.

    2012-04-01

    Machine prognosis can be considered as the generation of long-term predictions that describe the evolution in time of a fault indicator, with the purpose of estimating the remaining useful life (RUL) of a failing component/subsystem so that timely maintenance can be performed to avoid catastrophic failures. This paper proposes an integrated RUL prediction method using adaptive neuro-fuzzy inference systems (ANFIS) and high-order particle filtering, which forecasts the time evolution of the fault indicator and estimates the probability density function (pdf) of RUL. The ANFIS is trained and integrated in a high-order particle filter as a model describing the fault progression. The high-order particle filter is used to estimate the current state and carry out p-step-ahead predictions via a set of particles. These predictions are used to estimate the RUL pdf. The performance of the proposed method is evaluated via the real-world data from a seeded fault test for a UH-60 helicopter planetary gear plate. The results demonstrate that it outperforms both the conventional ANFIS predictor and the particle-filter-based predictor where the fault growth model is a first-order model that is trained via the ANFIS.

  14. Long-term treatment of ADHD with stimulants: A large observational study of real-life patients

    DEFF Research Database (Denmark)

    Powell, Shelagh G.; Thomsen, Per Hove; Frydenberg, Morten

    2011-01-01

    : The diversity of ADHD patients was evident from the comorbidity, age at start, comedication, and treatment needs over time. Dosages corresponded to guidelines in most patients, but some needed higher dosages or got along on lower dosages for long periods. Age at start and comorbidity influenced dosage......, and dosage was associated to differential outcome groups. Conclusion: The study findings underscored the diversity of ADHD patients and that individual factors should be taken into account when tailoring individual treatment schedules. Findings further showed that stimulant dosages are dynamic over time......Objective: To evaluate 410 real-life patients treated with stimulants and assessed systematically over several years. Method: Naturalistic observational study. A database was compiled on the basis of a review of the medical charts of patients attending a specialized ADHD clinic. Results...

  15. The real-life experience with cardiovascular complications in the first dose of fingolimod for multiple sclerosis

    Directory of Open Access Journals (Sweden)

    Yara Dadalti Fragoso

    2014-09-01

    Full Text Available Fingolimod is a new and efficient treatment for multiple sclerosis (MS. The drug administration requires special attention to the first dose, since cardiovascular adverse events can be observed during the initial six hours of fingolimod ingestion. The present study consisted of a review of cardiovascular data on 180 patients with MS receiving the first dose of fingolimod. The rate of bradycardia in these patients was higher than that observed in clinical trials with very strict inclusion criteria for patients. There were less than 10% of cases requiring special attention, but no fatal cases. All but one patient continued the treatment after this initial dose. This is the first report on real-life administration of fingolimod to Brazilian patients with MS, and one of the few studies with these characteristics in the world.

  16. Productive criticism, Part 2: A new environment for criticism. Performance appraisals and other real-life situations.

    Science.gov (United States)

    Weisinger, H D

    1996-01-01

    Criticism affects almost all aspects of your job: the quality of work you do, how you feel about it, and your relationships with your boss, coworkers, and subordinates. Used productively, criticism is a powerful tool that helps you improve your work, enhance your working relationships, increase your job satisfaction, and achieve better overall results. Improperly used, it impedes performance, demoralizes you, discourages you from wanting to try again, and creates friction in the workplace. In short, the ability to give and take criticism significantly determines how well you do on the job. In Part 1, we explained how to use productive criticism as an opportunity for the growth and education of subordinates. In Part 2, we will examine how you can productively criticize superiors and peers. We will also offer new performance appraisal technics and examine real-life criticism situations.

  17. Healthy food choices are happy food choices: Evidence from a real life sample using smartphone based assessments.

    Science.gov (United States)

    Wahl, Deborah R; Villinger, Karoline; König, Laura M; Ziesemer, Katrin; Schupp, Harald T; Renner, Britta

    2017-12-06

    Research suggests that "healthy" food choices such as eating fruits and vegetables have not only physical but also mental health benefits and might be a long-term investment in future well-being. This view contrasts with the belief that high-caloric foods taste better, make us happy, and alleviate a negative mood. To provide a more comprehensive assessment of food choice and well-being, we investigated in-the-moment eating happiness by assessing complete, real life dietary behaviour across eight days using smartphone-based ecological momentary assessment. Three main findings emerged: First, of 14 different main food categories, vegetables consumption contributed the largest share to eating happiness measured across eight days. Second, sweets on average provided comparable induced eating happiness to "healthy" food choices such as fruits or vegetables. Third, dinner elicited comparable eating happiness to snacking. These findings are discussed within the "food as health" and "food as well-being" perspectives on eating behaviour.

  18. Grating-based guided-mode resonance devices and degradation of their performance in real-life conditions

    DEFF Research Database (Denmark)

    Ivinskaya, Aliaksandra; Bergmann, René; Kafka, Jan Robert

    2014-01-01

    Guided-mode resonances in structures having periodicity along at least one dimension were widely employed in the last decade in various optical devices. Initially it was shown that at frequencies close to the second order band gap periodic structures can feature total reflection of light due...... to the guided modes propagating along the surface of the grating. As an application, this allows to substitute a thick multilayer Bragg mirror in VCSELs by a thin grating-based mirror. Most devices utilizing guided-mode resonances were theoretically and numerically investigated with the idealized model...... of an infinite periodic structure illuminated by a plane wave. To see how grating-based components can perform in real life we take into account two critical factors: the finite size of the grating and the Gaussian shape of the light source replacing a plane wave. These factors can significantly change...

  19. The fragrance hand immersion study - an experimental model simulating real-life exposure for allergic contact dermatitis on the hands

    DEFF Research Database (Denmark)

    Heydorn, S; Menné, T; Andersen, K E

    2003-01-01

    previously diagnosed with hand eczema to explore whether immersion of fingers in a solution with or without the patch-test-positive fragrance allergen would cause or exacerbate hand eczema on the exposed finger. The study was double blinded and randomized. All participants had a positive patch test to either...... hydroxycitronellal or Lyral (hydroxyisohexyl 3-cyclohexene carboxaldehyde). Each participant immersed a finger from each hand, once a day, in a solution containing the fragrance allergen or placebo. During the first 2 weeks, the concentration of fragrance allergen in the solution was low (approximately 10 p...... meter. 3 of 15 hand eczema patients developed eczema on the finger immersed in the fragrance-containing solution, 3 of 15 on the placebo finger and 3 of 15 on both fingers. Using this experimental exposure model simulating real-life exposure, we found no association between immersion of a finger...

  20. Recovery of real dye bath wastewater using integrated membrane process: considering water recovery, membrane fouling and reuse potential of membranes.

    Science.gov (United States)

    Balcik-Canbolat, Cigdem; Sengezer, Cisel; Sakar, Hacer; Karagunduz, Ahmet; Keskinler, Bulent

    2017-11-01

    It has been recognized by the whole world that textile industry which produce large amounts of wastewater with strong color and toxic organic compounds is a major problematical industry requiring effective treatment solutions. In this study, reverse osmosis (RO) membranes were tested on biologically treated real dye bath wastewater with and without pretreatment by nanofiltration (NF) membrane to recovery. Also membrane fouling and reuse potential of membranes were investigated by multiple filtrations. Obtained results showed that only NF is not suitable to produce enough quality to reuse the wastewater in a textile industry as process water while RO provide successfully enough permeate quality. The results recommend that integrated NF/RO membrane process is able to reduce membrane fouling and allow long-term operation for real dye bath wastewater.

  1. Real life study of three years omalizumab in patients with difficult-to-control asthma.

    Science.gov (United States)

    López Tiro, J Jesús; Contreras, E Angélica Contreras; del Pozo, M Elena Ramírez; Gómez Vera, J; Larenas Linnemann, D

    2015-01-01

    Even though there are multiple options for the treatment of asthma, there still exists a fair group of patients with difficult-to-control asthma. We describe for the first time the real-world effects of three-year omalizumab treatment on patients with difficult-to-control asthma, seen in a social security hospital in a Latin American country. Difficult-to-control asthmatic patients from the out-patient clinic of a regional hospital were recruited to receive a three-year omalizumab course. Efficacy parameters were asthma control test (ACT) score; FEV1; daily beclomethasone maintenance dose; and unplanned visits for asthma exacerbations (emergency room (ER), hospitalisations, intensive care). 52 patients were recruited, 47 completed the three-year treatment (42 female, 15-67 years, mean age 43.5). Comparing efficacy parameters of the year before omalizumab with the 3rd year of omalizumab: mean ACT improved from 12.4 to 20.5, mean FEV1 from 66.3% (standard deviation (SD) 19.1%) to 88.4% (SD 16.2%) of predicted, while mean beclomethasone dose reduced from 1750 to 766 mcg/day and there was a significant reduction in patients experiencing ER visits (from 95% to 19%, pomalizumab, two because of an adverse event (anaphylaxis, severe headache, both resolved without sequelae). Omalizumab improved most clinical parameters of Mexican patients with difficult-to-control asthma. Especially the rates of ER visits and hospitalisation were significantly reduced, thus reducing costs. Omalizumab was generally well tolerated. Copyright © 2013 SEICAP. Published by Elsevier Espana. All rights reserved.

  2. Design of a robotized workstation making use of the integration of CAD models and Robotic Simulation software as way of pairing and comparing real and virtual environments

    Directory of Open Access Journals (Sweden)

    Velíšek Karol

    2017-01-01

    Full Text Available Over the last years, there has been an increasing tendency and pressure on the faster implementation robotic devices and systems in manufacturing. Such transition involves several disciplines starting with the prototyping of CAD models itself. The paper addresses the creation of CAD models and is mainly aimed at their integration in a given simulation environment according to the conception and guidelines of Industry 4.0, where the part itself becomes the entity carrying most of the needed information at any time of a production process. The creation of such CAD models is key for the further and better customization of simulations. In other to better exemplify all this, the paper describes the whole process of “virtual to real life implementation” of a given robotized workplace needed to be developed at the Institute. The design of such robotized workplace included the use of an ABB IRB 120 robot and several other devices which were all designed, simulated and analyzed in a virtual environment before the final development and implementation. This paper helped demonstrating the importance of having exactly the same model (real and virtual with respect to the success of the offline simulations.

  3. Integrating life cycle assessment into managing potential EHS risks of engineered nanomaterials: reviewing progress to date

    International Nuclear Information System (INIS)

    Walker, William C.; Bosso, Christopher J.; Eckelman, Matthew; Isaacs, Jacqueline A.; Pourzahedi, Leila

    2015-01-01

    The 2011 National Nanotechnology Initiative’s Environmental Health and Safety Research Strategy stressed the need for research to integrate life cycle considerations into risk management and, then, to better integrate risk assessment into decisionmaking on environmental, health, and safety (EHS) dimensions of nanomanufacturing. This paper reviews scholarly articles published 2010–2015 that in some way apply life cycle analysis to nanotechnology to assess the extent to which current research reflects the priorities lain out in the NNI report. As the NNI’s focus was primarily on the “responsible development of nanotechnology” we also focus our examination on the ways in which LCA, in concert with other methodologies, can provide utility to decision makers facing the challenge of implementing that broad goal. We explore some of the challenges and opportunities inherent in using LCA, a tool built to optimize manufacturing decisions, as a guide for policy formulation or tool for policy implementation

  4. Integrating life cycle assessment into managing potential EHS risks of engineered nanomaterials: reviewing progress to date

    Energy Technology Data Exchange (ETDEWEB)

    Walker, William C.; Bosso, Christopher J., E-mail: c.bosso@neu.edu [Northeastern University, School of Public Policy and Urban Affairs (United States); Eckelman, Matthew [Northeastern University, Department of Civil and Environmental Engineering (United States); Isaacs, Jacqueline A. [Northeastern University, Department of Mechanical and Industrial Engineering (United States); Pourzahedi, Leila [Northeastern University, Department of Civil and Environmental Engineering (United States)

    2015-08-15

    The 2011 National Nanotechnology Initiative’s Environmental Health and Safety Research Strategy stressed the need for research to integrate life cycle considerations into risk management and, then, to better integrate risk assessment into decisionmaking on environmental, health, and safety (EHS) dimensions of nanomanufacturing. This paper reviews scholarly articles published 2010–2015 that in some way apply life cycle analysis to nanotechnology to assess the extent to which current research reflects the priorities lain out in the NNI report. As the NNI’s focus was primarily on the “responsible development of nanotechnology” we also focus our examination on the ways in which LCA, in concert with other methodologies, can provide utility to decision makers facing the challenge of implementing that broad goal. We explore some of the challenges and opportunities inherent in using LCA, a tool built to optimize manufacturing decisions, as a guide for policy formulation or tool for policy implementation.

  5. The application of life cycle assessment to integrated solid waste management. Pt. 1: Methodology

    Energy Technology Data Exchange (ETDEWEB)

    Clift, R.; Doig, A.; Finnveden, G.

    2000-07-01

    Integrated Waste Management is one of the holistic approaches to environmental and resource management which are emerging from applying the concept of sustainable development. Assessment of waste management options requires application of Life Cycle Assessment (LCA). This paper summarizes the methodology for applying LCA to Integrated Waste Management of Municipal Solid Wastes (MSW) developed for and now used by the UK Environment Agency, including recent developments in international fora. Particular attention is devoted to system definition leading to rational and clear compilation of the Life Cycle Inventory, with appropriate 'credit' for recovering materials and/or energy from the waste. LCA of waste management is best seen as a way of structuring information to help decision processes. (Author)

  6. Integrated waste management and the tool of life cycle inventory : a route to sustainable waste management

    Energy Technology Data Exchange (ETDEWEB)

    McDougall, F.R.; White, P.R. [Procter and Gamble Newcastle Technical Centre, Newcastle (United Kingdom). Corporate Sustainable Development

    2000-07-01

    An overall approach to municipal waste management which integrates sustainable development principles was discussed. The three elements of sustainability which have to be balanced are environmental effectiveness, economic affordability and social acceptability. An integrated waste management (IWM) system considers different treatment options and deals with the entire waste stream. A life cycle inventory (LCI) and life cycle assessment (LCA) is used to determine the environmental burdens associated with IWM systems. LCIs for waste management are currently available for use in Europe, the United States, Canada and elsewhere. LCI is being used by waste management companies to assess the environmental attributes of future contract tenders. The models are used as benchmarking tools to assess the current environmental profile of a waste management system. They are also a comparative planning and communication tool. The authors are currently looking into publishing, at a future date, the experience of users of this LCI environmental management tool. 12 refs., 3 figs.

  7. The fragrance hand immersion study - an experimental model simulating real-life exposure for allergic contact dermatitis on the hands.

    Science.gov (United States)

    Heydorn, S; Menné, T; Andersen, K E; Bruze, M; Svedman, C; Basketter, D; Johansen, J D

    2003-06-01

    Recently, we showed that 10 x 2% of consecutively patch-tested hand eczema patients had a positive patch test to a selection of fragrances containing fragrances relevant to hand exposure. In this study, we used repeated skin exposure to a patch test-positive fragrance allergen in patients previously diagnosed with hand eczema to explore whether immersion of fingers in a solution with or without the patch-test-positive fragrance allergen would cause or exacerbate hand eczema on the exposed finger. The study was double blinded and randomized. All participants had a positive patch test to either hydroxycitronellal or Lyral (hydroxyisohexyl 3-cyclohexene carboxaldehyde). Each participant immersed a finger from each hand, once a day, in a solution containing the fragrance allergen or placebo. During the first 2 weeks, the concentration of fragrance allergen in the solution was low (approximately 10 p.p.m.), whilst during the following 2 weeks, the concentration was relatively high (approximately 250 p.p.m.), imitating real-life exposure to a household product like dishwashing liquid diluted in water and the undiluted product, respectively. Evaluation was made using a clinical scale and laser Doppler flow meter. 3 of 15 hand eczema patients developed eczema on the finger immersed in the fragrance-containing solution, 3 of 15 on the placebo finger and 3 of 15 on both fingers. Using this experimental exposure model simulating real-life exposure, we found no association between immersion of a finger in a solution containing fragrance and development of clinically visible eczema on the finger in 15 participants previously diagnosed with hand eczema and with a positive patch test to the fragrance in question.

  8. A Novel Computational Tool for Mining Real-Life Data: Application in the Metastatic Colorectal Cancer Care Setting.

    Science.gov (United States)

    Siegelmann-Danieli, Nava; Farkash, Ariel; Katzir, Itzhak; Vesterman Landes, Janet; Rotem Rabinovich, Hadas; Lomnicky, Yossef; Carmeli, Boaz; Parush-Shear-Yashuv, Naama

    2016-01-01

    Randomized clinical trials constitute the gold-standard for evaluating new anti-cancer therapies; however, real-life data are key in complementing clinically useful information. We developed a computational tool for real-life data analysis and applied it to the metastatic colorectal cancer (mCRC) setting. This tool addressed the impact of oncology/non-oncology parameters on treatment patterns and clinical outcomes. The developed tool enables extraction of any computerized information including comorbidities and use of drugs (oncological/non-oncological) per individual HMO member. The study in which we evaluated this tool was a retrospective cohort study that included Maccabi Healthcare Services members with mCRC receiving bevacizumab with fluoropyrimidines (FP), FP plus oxaliplatin (FP-O), or FP plus irinotecan (FP-I) in the first-line between 9/2006 and 12/2013. The analysis included 753 patients of whom 15.4% underwent subsequent metastasectomy (the Surgery group). For the entire cohort, median overall survival (OS) was 20.5 months; in the Surgery group, median duration of bevacizumab-containing therapy (DOT) pre-surgery was 6.1 months; median OS was not reached. In the Non-surgery group, median OS and DOT were 18.7 and 11.4 months, respectively; no significant OS differences were noted between FP-O and FP-I, whereas FP use was associated with shorter OS (12.3 month; p controlling for age and gender) identified several non-oncology parameters associated with poorer clinical outcomes including concurrent use of diuretics and proton-pump inhibitors. Our tool provided insights that confirmed/complemented information gained from randomized-clinical trials. Prospective tool implementation is warranted.

  9. Efficacy and safety of topical NSAIDs in the management of osteoarthritis: Evidence from real-life setting trials and surveys.

    Science.gov (United States)

    Rannou, François; Pelletier, Jean-Pierre; Martel-Pelletier, Johanne

    2016-02-01

    Topical non-steroidal anti-inflammatory drugs (NSAIDs) are recommended in international and national guidelines as an early treatment option for the symptomatic management of knee and hand osteoarthritis (OA), and may be used ahead of oral NSAIDs due to their superior safety profile. The European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) treatment algorithm recommends topical NSAIDs for knee OA in addition to the pharmacological background of symptomatic slow-acting drugs for osteoarthritis (SYSADOAs) and rescue analgesia with paracetamol and non-pharmacological treatment, if the patient is still symptomatic. Topical NSAIDs have a moderate effect on pain relief, with efficacy similar to that of oral NSAIDs, with the advantage of a better risk:benefit ratio. In real-life studies, topical and oral NSAIDs demonstrate an equivalent effect on knee pain over 1 year of treatment, with fewer adverse events due to lower systemic absorption of topical NSAIDs compared with oral NSAIDs. As a result, topical NSAIDs may be the preferred treatment option, especially in OA patients aged ≥75 years, and those with co-morbidities or at an increased risk of cardiovascular, gastrointestinal, or renal side effects. Furthermore, using topical NSAIDs in inflammatory rheumatic diseases leads to a 40% reduction in the need for concomitant oral NSAIDs. When selecting a topical NSAID, absorption and bioavailability are important because of heterogeneity among topical drug formulations. Molecules like etofenamate have a bioavailability of >20% and evidence for accumulation in synovial tissues, with efficacy demonstrated as improvement in pain and function in real-life studies of OA patients. Diclofenac also shows good efficacy alongside evidence that diclofenac accumulates in the synovium. Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.

  10. Treatment Efficacy and Compliance in Patients with Diabetic Macular Edema Treated with Ranibizumab in a Real-Life Setting

    Directory of Open Access Journals (Sweden)

    Anne-Laurence Best

    2018-01-01

    Full Text Available Purpose. To assess real-life efficacy of ranibizumab and treatment compliance of patients with vision loss secondary to diabetic macular edema (DME. Methods. A retrospective study was conducted in DME patients treated with ranibizumab. Patients were monitored every 4 weeks for visual acuity (VA and central retinal thickness (CRT by SD-OCT. All patients received a loading dose of 3 monthly injections followed by retreatments on an as-needed basis. The primary endpoint was the change in VA at M12. Patient compliance to the follow-up and the correlation between the injection number and VA were also investigated. Compliance was compared to that of neovascular age-related macular degeneration (nAMD patients. Results. Seventy-two eyes of 55 consecutive DME patients were included. At baseline, the mean VA was 56.5 letters and CRT was 470 μm. At M12, the mean VA was 63.4 letters (p 70 letters, the mean VA change was +6.9 letters, and the mean CRT was 361.9 μm (p=0.0001 after a mean number of 5.33 intravitreal injections. In patients who received ≥7 injections, the VA gain and final VA were significantly higher than in patients who received <7 injections. At M12, 25.45% of DME patients were lost to follow-up versus 16.8% of nAMD patients (n=55. Discussion/Conclusion. Our study confirms the real-life efficacy of ranibizumab in DME at M12 and the need for a large number of injections to achieve better visual outcomes. We also showed a trend to a lower compliance in diabetic versus nAMD patients.

  11. How does age-related macular degeneration affect real-world visual ability and quality of life? A systematic review

    Science.gov (United States)

    Taylor, Deanna J; Hobby, Angharad E; Binns, Alison M; Crabb, David P

    2016-01-01

    Objectives To review systematically the evidence of age-related macular degeneration (AMD) affecting real-world visual ability and quality of life (QoL). To explore trends in specific topics within this body of the literature. Design Systematic review. Methods A systematic literature search was carried out using MEDLINE, EMBASE, CINAHL, PsycINFO, PsychARTICLES and Health and Psychosocial Instruments for articles published up to January 2015 for studies including people diagnosed with AMD, assessing real-world visual ability or QoL as an outcome. Two researchers screened studies for eligibility. Details of eligible studies including study design, characteristics of study population and outcomes measured were recorded in a data extraction table. All included studies underwent quality appraisal using the Mixed Methods Appraisal Tool 2011 Version (MMAT). Results From 5284 studies, 123 were eligible for inclusion. A range of approaches were identified, including performance-based methods, quantitative and qualitative patient-reported outcome measures (PROMs). AMD negatively affects tasks including mobility, face recognition, perception of scenes, computer use, meal preparation, shopping, cleaning, watching TV, reading, driving and, in some cases, self-care. There is evidence for higher rates of depression among people with AMD than among community dwelling elderly. A number of adaptation strategies have been associated with AMD of varying duration. Much of the research fails to report the type of AMD studied (59% of included studies) or the duration of disease in participants (74%). Of those that do report type studied, the breakdown is as follows: wet AMD 20%, dry AMD 4% and both types 17%. Conclusions There are many publications highlighting the negative effects of AMD in various domains of life. Future research should focus on delivering some of this research knowledge into patient management and clinical trials and differentiating between the types of AMD. PMID

  12. The frequency and determinants of liver stiffness measurement failure: a retrospective study of "real-life" 38,464 examinations.

    Directory of Open Access Journals (Sweden)

    Dong Ji

    Full Text Available To investigate the frequency and determinants of liver stiffness measurement (LSM failure by means of FibroScan in "real-life" Chinese patients.A total of 38,464 "real-life" Chinese patients in 302 military hospital of China through the whole year of 2013, including asymptomatic carrier, chronic hepatitis B, chronic hepatitis C, liver cirrhosis (LC, alcoholic liver disease, autoimmune liver disease, hepatocellular carcinoma (HCC and other, were enrolled, their clinical and biological parameters were retrospectively investigated. Liver fibrosis was evaluated by FibroScan detection. S probe (for children with height less than 1.20 m and M probe (for adults were used. LSM failure defined as zero valid shots (unsuccessful LSM, or the ratio of the interquartile range to the median of 10 measurements (IQR/M greater than 0.30 plus median LSM greater or equal to 7.1 kPa (unreliable LSM.LSM failure occurred in 3.34% of all examinations (1286 patients out of 38,464, among them, there were 958 cases (2.49% with unsuccessful LSM, and 328 patients (0.85% with unreliable LSM. Statistical analyses showed that LSM failure was independently associated with body mass index (BMI greater than 30 kg/m(2, female sex, age greater than 50 years, intercostal spaces (IS less than 9 mm, decompensated liver cirrhosis and HCC patients. There were no significant differences among other diseases. By changing another skilled operator, success was achieved on 301 cases out of 1286, which reduced the failure rate to 2.56%, the decrease was significant (P<0.0001.The principal reasons of LSM failure are ascites, obesity and narrow of IS. The failure rates of HCC, decompensated LC, elder or female patients are higher. These results emphasize the need for adequate operator training, technological improvements and optimal criteria for specific patient subpopulations.

  13. Shelf-life prediction models for ready-to-eat fresh cut salads: Testing in real cold chain.

    Science.gov (United States)

    Tsironi, Theofania; Dermesonlouoglou, Efimia; Giannoglou, Marianna; Gogou, Eleni; Katsaros, George; Taoukis, Petros

    2017-01-02

    The aim of the study was to develop and test the applicability of predictive models for shelf-life estimation of ready-to-eat (RTE) fresh cut salads in realistic distribution temperature conditions in the food supply chain. A systematic kinetic study of quality loss of RTE mixed salad (lollo rosso lettuce-40%, lollo verde lettuce-45%, rocket-15%) packed under modified atmospheres (3% O 2 , 10% CO 2 , 87% N 2 ) was conducted. Microbial population (total viable count, Pseudomonas spp., lactic acid bacteria), vitamin C, colour and texture were the measured quality parameters. Kinetic models for these indices were developed to determine the quality loss and calculate product remaining shelf-life (SL R ). Storage experiments were conducted at isothermal (2.5-15°C) and non-isothermal temperature conditions (T eff =7.8°C defined as the constant temperature that results in the same quality value as the variable temperature distribution) for validation purposes. Pseudomonas dominated spoilage, followed by browning and chemical changes. The end of shelf-life correlated with a Pseudomonas spp. level of 8 log(cfu/g), and 20% loss of the initial vitamin C content. The effect of temperature on these quality parameters was expressed by the Arrhenius equation; activation energy (E a ) value was 69.1 and 122.6kJ/mol for Pseudomonas spp. growth and vitamin C loss rates, respectively. Shelf-life prediction models were also validated in real cold chain conditions (including the stages of transport to and storage at retail distribution center, transport to and display at 7 retail stores, transport to and storage in domestic refrigerators). The quality level and SL R estimated after 2-3days of domestic storage (time of consumption) ranged between 1 and 8days at 4°C and was predicted within satisfactory statistical error by the kinetic models. T eff in the cold chain ranged between 3.7 and 8.3°C. Using the validated models, SL R of RTE fresh cut salad can be estimated at any point of

  14. The ADAQ framework: An integrated toolkit for data acquisition and analysis with real and simulated radiation detectors

    International Nuclear Information System (INIS)

    Hartwig, Zachary S.

    2016-01-01

    The ADAQ framework is a collection of software tools that is designed to streamline the acquisition and analysis of radiation detector data produced in modern digital data acquisition (DAQ) systems and in Monte Carlo detector simulations. The purpose of the framework is to maximize user scientific productivity by minimizing the effort and expertise required to fully utilize radiation detectors in a variety of scientific and engineering disciplines. By using a single set of tools to span the real and simulation domains, the framework eliminates redundancy and provides an integrated workflow for high-fidelity comparison between experimental and simulated detector performance. Built on the ROOT data analysis framework, the core of the ADAQ framework is a set of C++ and Python libraries that enable high-level control of digital DAQ systems and detector simulations with data stored into standardized binary ROOT files for further analysis. Two graphical user interface programs utilize the libraries to create powerful tools: ADAQAcquisition handles control and readout of real-world DAQ systems and ADAQAnalysis provides data analysis and visualization methods for experimental and simulated data. At present, the ADAQ framework supports digital DAQ hardware from CAEN S.p.A. and detector simulations performed in Geant4; however, the modular design will facilitate future extension to other manufacturers and simulation platforms. - Highlights: • A new software framework for radiation detector data acquisition and analysis. • Integrated acquisition and analysis of real-world and simulated detector data. • C++ and Python libraries for data acquisition hardware control and readout. • Graphical program for control and readout of digital data acquisition hardware. • Graphical program for comprehensive analysis of real-world and simulated data.

  15. The ADAQ framework: An integrated toolkit for data acquisition and analysis with real and simulated radiation detectors

    Energy Technology Data Exchange (ETDEWEB)

    Hartwig, Zachary S., E-mail: hartwig@mit.edu

    2016-04-11

    The ADAQ framework is a collection of software tools that is designed to streamline the acquisition and analysis of radiation detector data produced in modern digital data acquisition (DAQ) systems and in Monte Carlo detector simulations. The purpose of the framework is to maximize user scientific productivity by minimizing the effort and expertise required to fully utilize radiation detectors in a variety of scientific and engineering disciplines. By using a single set of tools to span the real and simulation domains, the framework eliminates redundancy and provides an integrated workflow for high-fidelity comparison between experimental and simulated detector performance. Built on the ROOT data analysis framework, the core of the ADAQ framework is a set of C++ and Python libraries that enable high-level control of digital DAQ systems and detector simulations with data stored into standardized binary ROOT files for further analysis. Two graphical user interface programs utilize the libraries to create powerful tools: ADAQAcquisition handles control and readout of real-world DAQ systems and ADAQAnalysis provides data analysis and visualization methods for experimental and simulated data. At present, the ADAQ framework supports digital DAQ hardware from CAEN S.p.A. and detector simulations performed in Geant4; however, the modular design will facilitate future extension to other manufacturers and simulation platforms. - Highlights: • A new software framework for radiation detector data acquisition and analysis. • Integrated acquisition and analysis of real-world and simulated detector data. • C++ and Python libraries for data acquisition hardware control and readout. • Graphical program for control and readout of digital data acquisition hardware. • Graphical program for comprehensive analysis of real-world and simulated data.

  16. Effect of Continuous Glucose Monitoring on Glycemic Control, Acute Admissions, and Quality of Life: A Real-World Study.

    Science.gov (United States)

    Charleer, Sara; Mathieu, Chantal; Nobels, Frank; De Block, Christophe; Radermecker, Regis P; Hermans, Michel P; Taes, Youri; Vercammen, Chris; T'Sjoen, Guy; Crenier, Laurent; Fieuws, Steffen; Keymeulen, Bart; Gillard, Pieter

    2018-03-01

    Randomized controlled trials evaluating real-time continuous glucose monitoring (RT-CGM) patients with type 1 diabetes (T1D) show improved glycemic control, but limited data are available on real-world use. To assess impact of RT-CGM in real-world settings on glycemic control, hospital admissions, work absenteeism, and quality of life (QOL). Prospective, observational, multicenter, cohort study. A total of 515 adults with T1D on continuous subcutaneous insulin infusion (CSII) therapy starting in the Belgian RT-CGM reimbursement program. Initiation of RT-CGM reimbursement. Hemoglobin A1c (HbA1c) evolution from baseline to 12 months. Between September 1, 2014, and December 31, 2016, 515 adults entered the reimbursement system. Over this period, 417 (81%) patients used RT-CGM for at least 12 months. Baseline HbA1c was 7.7 ± 0.9% (61 ± 9.8 mmol/mol) and decreased to 7.4 ± 0.8% (57 ± 8.7 mmol/mol) at 12 months (P < 0.0001). Subjects who started RT-CGM because of insufficient glycemic control showed stronger decrease in HbA1c at 4, 8, and 12 months compared with patients who started because of hypoglycemia or pregnancy. In the year preceding reimbursement, 16% of patients were hospitalized for severe hypoglycemia or ketoacidosis in contrast to 4% (P < 0.0005) the following year, with decrease in admission days from 54 to 18 per 100 patient years (P < 0.0005). In the same period, work absenteeism decreased and QOL improved significantly, with strong decline in fear of hypoglycemia. Sensor-augmented pump therapy in patients with T1D followed in specialized centers improves HbA1c, fear of hypoglycemia, and QOL, whereas work absenteeism and admissions for acute diabetes complications decreased.

  17. Quality of life of Brazilian and Spanish cancer patients undergoing chemotherapy: an integrative literature review.

    Science.gov (United States)

    Sawada, Namie Okino; Nicolussi, Adriana Cristina; de Paula, Juliana Maria; Garcia-Caro, Maria Paz; Marti-Garcia, Celia; Cruz-Quintana, Francisco

    2016-01-01

    characterize the scientific production of Brazil and Spain in regard to methodological aspects and aspects of health-related quality of life experienced by cancer patients receiving chemotherapy in both countries. integrative literature review was conducted using the following databases: CINAHL, MEDLINE, SCOPUS and CUIDEN and the electronic libraries PubMed and SciELO, conducted in September 2013. a total of 28 papers met the inclusion criteria. The synthesis of knowledge was presented in three categories of analysis: assessment of quality of life in different types of cancer; sociodemographic factors that influenced quality of life; and type of cancer and interventions that improve quality of life. Chemotherapy affects health-related quality of life and the most important factors were: age, sex, chemotherapy protocol, type of surgery, stage of the disease, educational level, and emotional intelligence. Complementary therapies such as acupuncture, guided visualization, prayers and exercise were positive and reduced side effects. the results showed a poor level of evidence, since 86% of the studies were cross-sectional descriptive studies; the instrument most frequently used to measure health-related quality of life was EORTC QLQ C-30 and more studies were conducted in Brazil than in Spain.

  18. Quality of life of Brazilian and Spanish cancer patients undergoing chemotherapy: an integrative literature review

    Science.gov (United States)

    Sawada, Namie Okino; Nicolussi, Adriana Cristina; de Paula, Juliana Maria; Garcia-Caro, Maria Paz; Marti-Garcia, Celia; Cruz-Quintana, Francisco

    2016-01-01

    Objective: characterize the scientific production of Brazil and Spain in regard to methodological aspects and aspects of health-related quality of life experienced by cancer patients receiving chemotherapy in both countries. Method: integrative literature review was conducted using the following databases: CINAHL, MEDLINE, SCOPUS and CUIDEN and the electronic libraries PubMed and SciELO, conducted in September 2013. Results: a total of 28 papers met the inclusion criteria. The synthesis of knowledge was presented in three categories of analysis: assessment of quality of life in different types of cancer; sociodemographic factors that influenced quality of life; and type of cancer and interventions that improve quality of life. Chemotherapy affects health-related quality of life and the most important factors were: age, sex, chemotherapy protocol, type of surgery, stage of the disease, educational level, and emotional intelligence. Complementary therapies such as acupuncture, guided visualization, prayers and exercise were positive and reduced side effects. Conclusion: the results showed a poor level of evidence, since 86% of the studies were cross-sectional descriptive studies; the instrument most frequently used to measure health-related quality of life was EORTC QLQ C-30 and more studies were conducted in Brazil than in Spain. PMID:27192414

  19. Power requirements and environmental impact of a pedelec. A case study based on real-life applications

    Energy Technology Data Exchange (ETDEWEB)

    Abagnale, Carmelina, E-mail: c.abagnale@unina.it; Cardone, Massimo, E-mail: massimo.cardone@unina.it; Iodice, Paolo, E-mail: paolo.iodice@unina.it; Strano, Salvatore, E-mail: salvatore.strano@unina.it; Terzo, Mario, E-mail: m.terzo@unina.it; Vorraro, Giovanni, E-mail: giovanni.vorraro@unina.it

    2015-07-15

    This paper describes the methodologies to appraise the power requests and environmental analysis of an electrically assisted bicycle under real driving conditions, also containing regulations and technical-science-related aspects. For this purpose, in this study, the on-road test program of an electrically assisted bicycle was executed in the urban area of Naples on different test tracks, so a general assessment about its driving behavior under several driving conditions was performed. The power requirements in different typical riding situations were estimated by a procedure based on the experimental kinematic parameters that characterize the driving dynamics collected during the real-life applications. An environmental analysis was also performed, with a methodology that takes into account the environmental assessment of a moped by measuring the experimental moped exhaust emissions of the regulated pollutants. Starting from the results acquired during the different test samples, besides, an assessment of the electric traction offered by this pedelec on the driving comfort was evaluated for different riding situations. - Highlights: • The power requirements of a pedelec in typical riding conditions were identified. • The estimated electricity consumption for battery recharging was defined. • An environmental valuation of the tested pedelec and of a moped was performed. • Emissions that could be saved utilizing a pedelec instead of a moped were derived.

  20. Comparison between particulate matter and ultrafine particle emission by electronic and normal cigarettes in real-life conditions.

    Science.gov (United States)

    Ruprecht, Ario Alberto; De Marco, Cinzia; Pozzi, Paolo; Munarini, Elena; Mazza, Roberto; Angellotti, Giorgia; Turla, Francesca; Boffi, Roberto

    2014-01-01

    Electronic cigarettes may be safer than conventional cigarettes as they generate less indoor pollution in terms of particulate matter (PM); however, recent findings in experimental conditions demonstrated that secondhand exposure to PM may be expected from e-cigarette smoking. The aim of the present study was to investigate the emission of PM generated by e-cigarettes and normal cigarettes under real-life conditions. Real-time measurement and comparison of PM and ultrafine particles (UFP) generated by electronic cigarettes with and without nicotine and by normal cigarettes in a 50 m3 office of an Italian comprehensive cancer center was performed. PM mass as PM1, PM2.5, PM7, PM10, total suspended particles (TSP) in μg/m³ and UFP in number of particles per cubic centimeter from 10 to 1,000 nanometers were measured. Outdoor concentrations were measured contemporaneously to compensate for urban background changes. Regardless of their nicotine content, e-cigarettes generated lower PM levels than conventional cigarettes. Notably, nicotine-enriched e-cigarettes produced lower PM levels than their nicotine-free counterparts. E-cigarettes appear to generate less indoor pollution than normal cigarettes and may therefore be safer. Further studies are required to investigate the long-term health-related effects of secondhand e-cigarette exposure.

  1. Dose uniformity of budesonide Easyhaler® under simulated real-life conditions and with low inspiration flow rates.

    Science.gov (United States)

    Haikarainen, Jussi; Rytilä, Paula; Roos, Sirkku; Metsärinne, Sirpa; Happonen, Anita

    2017-01-01

    Budesonide Easyhaler® multidose dry powder inhaler is approved for the treatment of asthma. Objectives were to determine the delivered dose (DD) uniformity of budesonide Easyhaler® in simulated real-world conditions and with different inspiration flow rates (IFRs). Three dose delivery studies were performed using 100, 200, and 400 µg/dose strengths of budesonide. Dose uniformity was assessed during in-use periods of 4-6 months after exposure to high temperature (30°C) and humidity (60% relative humidity) and after dropping and vibration testing. The influence of various IFRs (31, 43, and 54 L/min) on the DD was also investigated. Acceptable dose uniformity was declared when mean DD were within 80-120% of expected dose; all data reported descriptively. DD was constant (range: 93-109% of expected dose) at all in-use periods and after exposure to high temperature and humidity for a duration of up to 6 months. DD post-dropping and -vibration were unaffected (range 98-105% of expected dose). Similarly, DD was constant and within 10% of expected dose across all IFRs. Results indicate that budesonide Easyhaler® delivers consistently accurate doses in various real-life conditions. Budesonide Easyhaler® can be expected to consistently deliver a uniform dose and improve asthma control regardless of high temperature and humidity or varying IFR.

  2. Power requirements and environmental impact of a pedelec. A case study based on real-life applications

    International Nuclear Information System (INIS)

    Abagnale, Carmelina; Cardone, Massimo; Iodice, Paolo; Strano, Salvatore; Terzo, Mario; Vorraro, Giovanni

    2015-01-01

    This paper describes the methodologies to appraise the power requests and environmental analysis of an electrically assisted bicycle under real driving conditions, also containing regulations and technical-science-related aspects. For this purpose, in this study, the on-road test program of an electrically assisted bicycle was executed in the urban area of Naples on different test tracks, so a general assessment about its driving behavior under several driving conditions was performed. The power requirements in different typical riding situations were estimated by a procedure based on the experimental kinematic parameters that characterize the driving dynamics collected during the real-life applications. An environmental analysis was also performed, with a methodology that takes into account the environmental assessment of a moped by measuring the experimental moped exhaust emissions of the regulated pollutants. Starting from the results acquired during the different test samples, besides, an assessment of the electric traction offered by this pedelec on the driving comfort was evaluated for different riding situations. - Highlights: • The power requirements of a pedelec in typical riding conditions were identified. • The estimated electricity consumption for battery recharging was defined. • An environmental valuation of the tested pedelec and of a moped was performed. • Emissions that could be saved utilizing a pedelec instead of a moped were derived

  3. Living donor transplantation--the real gift of life. Procurement and the ethical assessment.

    Science.gov (United States)

    Banasik, Mirosław

    2006-01-01

    It has been observed during the past 10-15 years a greater disparity between the supply of kidneys for transplantation and the demand of patients on waiting lists. The number of cadaveric kidneys available for transplantation have not increased in many countries. Countries and their societies are faced with a choice, let patients with the end- stage renal disease stay on, dialysis giving a faster death and a lower quality of life, or decide to introduce the more active living donation program. There are countries, historically Scandinavian countries, the U.S.A. and U.K., which decided to change medical, social and ethical attitudes to help their citizens and patients on dialysis. For many other countries approval of the new approach of their donation seems to cause difficulties. The main problem for medical staff is the principle Primum non nocere (First do no harm), removal of a living kidney conflicts with this principle. From the other point of view is the human right of an individual to autonomy for donation of a kidney. The donor is completely informed for the risks involved in donation of a kidney to an awaiting recipient. The donors reasons for donation of the kidney must be understood and family pressure excluded. Where is the borderline between the paternalistic approach of the medical personnel preventing the altruistic attitude of the donor? How far is the role of the medical staff to extend in the assessment of the altruistic nature and goodwill of the donors?

  4. Perversion and perverse relationships in the filmic element: the unfinished between real and fantasmatic life

    Directory of Open Access Journals (Sweden)

    Chiara Bille

    2011-12-01

    Full Text Available The sadomasochist lives in an undifferentiated universe: a universe which assumes a complete equivalence and confusion between roles and erotic objects, in which incest is not prohibited, nor the distinction between inside and outside, between life and death. Following childhood traumas and abuses, sexual behavior with perverse aspects and the perverse structures that derive from it both move on common ground: that of the dehumanization of the emotional and sexual context, which principally consists in “thing-ifying” the Other in order to sustain arousal. The cinema can cue us as to what occurs in perversions and perverse relationships, precisely insofar as the unconscious material that fluctuates on the silver screen provides a clear representation of the entire world that the director inhabits: a world that is revived for the spectator in a space without time, in a “non-place” that acts as a backdrop to new meanings that remain undefined, incomplete and subject to change.

  5. Seen it in the Bulletin? Now see it in real-life!

    CERN Multimedia

    CERN Bulletin

    2013-01-01

    Detector Technologies (Map: C4): Read more about the construction and physics of the new NA62 straw chambers in “Straw Detector: 1 - Vacuum: 0”.   The Synchrocyclotron (Map: B2): Read more about the newly opened synchrocyclotron (SC) in “New life for CERN's first accelerator”.   Linac 4 (Map: D4): Visit the site of CERN’s newest linear accelerator: Linac4. Read more about the accelerator in “Linac4: the final assembly stage is under way” (2013), “Testing begins on Linac4” (2012), and “Sixteen silver wires to assemble 350 kg of copper” (2010).   Alpha Magnetic Spectrometer (AMS) (Map: I3): AMS is the most sensitive particle physics spectrometer ever deployed in space. Read about its launch in “AMS: From the ISS to CERN”.   COMPASS (Map: I1): COMPASS is a high-energy physics experiment at the SPS. Read more about its newest phase in ...

  6. An integrated life cycle sustainability assessment of electricity generation in Turkey

    International Nuclear Information System (INIS)

    Atilgan, Burcin; Azapagic, Adisa

    2016-01-01

    This paper presents for the first time an integrated life cycle sustainability assessment of the electricity sector in Turkey, considering environmental, economic and social aspects. Twenty life cycle sustainability indicators (11 environmental, three economic and six social) are used to evaluate the current electricity options. Geothermal power is the best option for six environmental impacts but it has the highest capital costs. Small reservoir and run-of-river power has the lowest global warming potential while large reservoir is best for the depletion of elements and fossil resources, and acidification. It also has the lowest levelised costs, worker injuries and fatalities but provides the lowest life cycle employment opportunities. Gas power has the lowest capital costs but it provides the lowest direct employment and has the highest levelised costs and ozone layer depletion. Given these trade-offs, a multi-criteria decision analysis has been carried out to identify the most sustainable options assuming different stakeholder preferences. For all the preferences considered, hydropower is the most sustainable option for Turkey, followed by geothermal and wind electricity. This work demonstrates the importance for energy policy of an integrated life cycle sustainability assessment and how tensions between different aspects can be reconciled to identify win-win solutions. - Highlights: •First integrated life cycle sustainability assessment of the electricity sector in Turkey. •11 environmental, three economic and six social sustainability indicators estimated. •Multi-criteria decision analysis carried out to identify most sustainable options. •Hydro is the most sustainable option for Turkey, followed by geothermal and wind. •This work demonstrates how tensions among sustainability aspects can be reconciled.

  7. Integrating Problem-Based Learning and Simulation: Effects on Student Motivation and Life Skills.

    Science.gov (United States)

    Roh, Young Sook; Kim, Sang Suk

    2015-07-01

    Previous research has suggested that a teaching strategy integrating problem-based learning and simulation may be superior to traditional lecture. The purpose of this study was to assess learner motivation and life skills before and after taking a course involving problem-based learning and simulation. The design used repeated measures with a convenience sample of 83 second-year nursing students who completed the integrated course. Data from a self-administered questionnaire measuring learner motivation and life skills were collected at pretest, post-problem-based learning, and post-simulation time points. Repeated-measures analysis of variance determined that the mean scores for total learner motivation (F=6.62, P=.003), communication (F=8.27, Plearning (F=4.45, P=.016) differed significantly between time points. Post hoc tests using the Bonferroni correction revealed that total learner motivation and total life skills significantly increased both from pretest to postsimulation and from post-problem-based learning test to postsimulation test. Subscales of learner motivation and life skills, intrinsic goal orientation, self-efficacy for learning and performance, problem-solving skills, and self-directed learning skills significantly increased both from pretest to postsimulation test and from post-problem-based learning test to post-simulation test. The results demonstrate that an integrating problem-based learning and simulation course elicits significant improvement in learner motivation and life skills. Simulation plus problem-based learning is more effective than problem-based learning alone at increasing intrinsic goal orientation, task value, self-efficacy for learning and performance, problem solving, and self-directed learning.

  8. Integrated approach for stress based lifing of aero gas turbine blades

    Science.gov (United States)

    Abu, Abdullahi Obonyegba

    In order to analyse the turbine blade life, the damage due to the combined thermal and mechanical loads should be adequately accounted for. This is more challenging when detailed component geometry is limited. Therefore, a compromise between the level of geometric detail and the complexity of the lifing method to be implemented would be necessary. This research focuses on how the life assessment of aero engine turbine blades can be done, considering the balance between available design inputs and adequate level of fidelity. Accordingly, the thesis contributes to developing a generic turbine blade lifing method that is based on the engine thermodynamic cycle; as well as integrating critical design/technological factors and operational parameters that influence the aero engine blade life. To this end, thermo-mechanical fatigue was identified as the critical damage phenomenon driving the life of the turbine blade.. The developed approach integrates software tools and numerical models created using the minimum design information typically available at the early design stages. Using finite element analysis of an idealised blade geometry, the approach captures relevant impacts of thermal gradients and thermal stresses that contribute to the thermo-mechanical fatigue damage on the gas turbine blade. The blade life is evaluated using the Neu/Sehitoglu thermo-mechanical fatigue model that considers damage accumulation due to fatigue, oxidation, and creep. The leading edge is examined as a critical part of the blade to estimate the damage severity for different design factors and operational parameters. The outputs of the research can be used to better understand how the environment and the operating conditions of the aircraft affect the blade life consumption and therefore what is the impact on the maintenance cost and the availability of the propulsion system. This research also finds that the environmental (oxidation) effect drives the blade life and the blade coolant

  9. Review of Real-time Electricity Markets for Integrating Distributed Energy Resources and Demand Response

    DEFF Research Database (Denmark)

    Wang, Qi; Zhang, Chunyu; Ding, Yi

    2015-01-01

    The high penetration of both Distributed Energy Resources (DER) and Demand Response (DR) in modern power systems requires a sequence of advanced strategies and technologies for maintaining system reliability and flexibility. Real-time electricity markets (RTM) are the nondiscriminatory transaction...... platforms for providing necessary balancing services, where the market clearing (nodal or zonal prices depending on markets) is very close to real time operations of power systems. One of the primary functions of RTMs in modern power systems is establishing an efficient and effective mechanism for small DER...... and DR to participate in balancing market transactions, while handling their meteorological or intermittent characteristics, facilitating asset utilization, and stimulating their active responses. Consequently, RTMs are dedicated to maintaining the flexibility and reliability of power systems. This paper...

  10. Real-time integration of control strategies for an isolated DFIG-based WECS

    Science.gov (United States)

    Bouchiba, Nouha; Barkia, Asma; Chrifi-Alaoui, Larbi; Drid, Saïd; Sallem, Souhir; Kammoun, M. B. A.

    2017-08-01

    This paper deals with voltage and frequency control of a stand-alone wind energy conversion system (WECS) based on a double fed induction generator (DFIG) under wind speed and load variations. In this context, two kinds of linear and nonlinear control strategies, classical PI and backstepping, have been applied to the system in real time. A series of experiments have been conducted to evaluate and to compare dynamic performances of the proposed control approaches. Experiments on a 1.5Kw doubly fed induction machine in real time are carried out using dSpace DS1104 card based on the MATLAB/Simulink environment. Experimental results show the validity of implemented controllers and demonstrate the effectiveness, the precision and the rapidity of the backstepping control strategy compared with the PI controller.

  11. LATENCY DETERMINATION AND COMPENSATION IN REAL-TIME GNSS/INS INTEGRATED NAVIGATION SYSTEMS

    Directory of Open Access Journals (Sweden)

    P. D. Solomon

    2012-09-01

    Full Text Available Unmanned Aerial Vehicle (UAV technology is now commonplace in many defence and civilian environments. However, the high cost of owning and operating a sophisticated UAV has slowed their adoption in many commercial markets. Universities and research groups are actively experimenting with UAVs to further develop the technology, particularly for automated flying operations. The two main UAV platforms used are fixed-wing and helicopter. Helicopter-based UAVs offer many attractive features over fixed-wing UAVs, including vertical take-off, the ability to loiter, and highly dynamic flight. However the control and navigation of helicopters are significantly more demanding than those of fixed-wing UAVs and as such require a high bandwidth real-time Position, Velocity, Attitude (PVA navigation system. In practical Real-Time Navigation Systems (RTNS there are delays in the processing of the GNSS data prior to the fusion of the GNSS data with the INS measurements. This latency must be compensated for otherwise it degrades the solution of the navigation filter. This paper investigates the effect of latency in the arrival time of the GNSS data in a RTNS. Several test drives and flights were conducted with a low-cost RTNS, and compared with a high quality GNSS/INS solution. A technique for the real-time, automated and accurate estimation of the GNSS latency in low-cost systems was developed and tested. The latency estimates were then verified through cross-correlation with the time-stamped measurements from the reference system. A delayed measurement Extended Kalman Filter was then used to allow for the real-time fusing of the delayed measurements, and then a final system developed for on-the-fly measurement and compensation of GNSS latency in a RTNS.

  12. Latency Determination and Compensation in Real-Time Gnss/ins Integrated Navigation Systems

    Science.gov (United States)

    Solomon, P. D.; Wang, J.; Rizos, C.

    2011-09-01

    Unmanned Aerial Vehicle (UAV) technology is now commonplace in many defence and civilian environments. However, the high cost of owning and operating a sophisticated UAV has slowed their adoption in many commercial markets. Universities and research groups are actively experimenting with UAVs to further develop the technology, particularly for automated flying operations. The two main UAV platforms used are fixed-wing and helicopter. Helicopter-based UAVs offer many attractive features over fixed-wing UAVs, including vertical take-off, the ability to loiter, and highly dynamic flight. However the control and navigation of helicopters are significantly more demanding than those of fixed-wing UAVs and as such require a high bandwidth real-time Position, Velocity, Attitude (PVA) navigation system. In practical Real-Time Navigation Systems (RTNS) there are delays in the processing of the GNSS data prior to the fusion of the GNSS data with the INS measurements. This latency must be compensated for otherwise it degrades the solution of the navigation filter. This paper investigates the effect of latency in the arrival time of the GNSS data in a RTNS. Several test drives and flights were conducted with a low-cost RTNS, and compared with a high quality GNSS/INS solution. A technique for the real-time, automated and accurate estimation of the GNSS latency in low-cost systems was developed and tested. The latency estimates were then verified through cross-correlation with the time-stamped measurements from the reference system. A delayed measurement Extended Kalman Filter was then used to allow for the real-time fusing of the delayed measurements, and then a final system developed for on-the-fly measurement and compensation of GNSS latency in a RTNS.

  13. General Forced Oscillations in a Real Power Grid Integrated with Large Scale Wind Power

    OpenAIRE

    Ping Ju; Yongfei Liu; Feng Wu; Fei Dai; Yiping Yu

    2016-01-01

    According to the monitoring of the wide area measurement system, inter-area oscillations happen more and more frequently in a real power grid of China, which are close to the forced oscillation. Applying the conventional forced oscillation theory, the mechanism of these oscillations cannot be explained well, because the oscillations vary with random amplitude and a narrow frequency band. To explain the mechanism of such oscillations, the general forced oscillation (GFO) mechanism is taken int...

  14. REAL-TIME MONITORING SYSTEM USING UNMANNED AERIAL VEHICLE INTEGRATED WITH SENSOR OBSERVATION SERVICE

    Directory of Open Access Journals (Sweden)

    A. Witayangkurn

    2012-09-01

    Full Text Available The Unmanned Aerial Vehicle (UAV is an emerging technology being adapted for a wide range of applications. Real-time monitoring is essential to enhance the effectiveness of UAV applications. Sensor networks are networks constructed from various sensor nodes. International standard such as OGC's SOS (Sensor Observation Service makes it possible to share sensor data with other systems as well as to provide accessibility to globally distributed users. In this paper, we propose a system combining UAV technology and sensor network technology to use an UAV as a mobile node of sensor network so that the sensor data from UAV is published and shared real-time. A UAV can extend the observation range of a sensor network to remote areas where it is usually difficult to access such as disaster area. We constructed a UAV system using remote-controlled helicopter and various sensors such as GPS, gyrocompass, laser range finder, Digital camera and Thermometer. Furthermore, we extended the Sensor Observation Service (SOS and Sensor Service Grid (SSG to support mobile sensor nodes. Then, we conducted experiments of flying the helicopter over an area of the interest. During the flight, the system measured environmental data using its sensors and captured images of the ground. The data was sent to a SOS node as the ground station via Wi-Fi which was published using SSG to give real- time access to globally distributed users.

  15. General Forced Oscillations in a Real Power Grid Integrated with Large Scale Wind Power

    Directory of Open Access Journals (Sweden)

    Ping Ju

    2016-07-01

    Full Text Available According to the monitoring of the wide area measurement system, inter-area oscillations happen more and more frequently in a real power grid of China, which are close to the forced oscillation. Applying the conventional forced oscillation theory, the mechanism of these oscillations cannot be explained well, because the oscillations vary with random amplitude and a narrow frequency band. To explain the mechanism of such oscillations, the general forced oscillation (GFO mechanism is taken into consideration. The GFO is the power system oscillation excited by the random excitations, such as power fluctuations from renewable power generation. Firstly, properties of the oscillations observed in the real power grid are analyzed. Using the GFO mechanism, the observed oscillations seem to be the GFO caused by some random excitation. Then the variation of the wind power measured in this power gird is found to be the random excitation which may cause the GFO phenomenon. Finally, simulations are carried out and the power spectral density of the simulated oscillation is compared to that of the observed oscillation, and they are similar with each other. The observed oscillation is thus explained well using the GFO mechanism and the GFO phenomenon has now been observed for the first time in real power grids.

  16. Real-life effectiveness of omalizumab in severe allergic asthma above the recommended dosing range criteria.

    Science.gov (United States)

    Hew, M; Gillman, A; Sutherland, M; Wark, P; Bowden, J; Guo, M; Reddel, H K; Jenkins, C; Marks, G B; Thien, F; Rimmer, J; Katsoulotos, G P; Cook, M; Yang, I; Katelaris, C; Bowler, S; Langton, D; Wright, C; Bint, M; Yozghatlian, V; Burgess, S; Sivakumaran, P; Yan, K Y; Kritikos, V; Peters, M; Baraket, M; Aminazad, A; Robinson, P; Jaffe, A; Powell, H; Upham, J W; McDonald, V M; Gibson, P G

    2016-11-01

    Omalizumab (Xolair) dosing in severe allergic asthma is based on serum IgE and bodyweight. In Australia, patients eligible for omalizumab but exceeding recommended ranges for IgE (30-1500 IU/mL) and bodyweight (30-150 kg) may still receive a ceiling dose of 750 mg/4 weeks. About 62% of patients receiving government-subsidized omalizumab are enrolled in the Australian Xolair Registry (AXR). To determine whether AXR participants above the recommended dosing ranges benefit from omalizumab and to compare their response to within-range participants. Data were stratified according to dose range status (above-range or within-range). Further sub-analyses were conducted according to the reason for being above the dosing range (IgE only vs. IgE and weight). Data for 179 participants were analysed. About 55 (31%) were above recommended dosing criteria; other characteristics were similar to within-range participants. Above-range participants had higher baseline IgE [812 (IQR 632, 1747) IU/mL vs. 209 (IQR 134, 306) IU/mL] and received higher doses of omalizumab [750 (IQR 650, 750) mg] compared to within-range participants [450 (IQR, 300, 600) mg]. At 6 months, improvements in Juniper 5-item Asthma Control Questionnaire (ACQ-5, 3.61 down to 2.01 for above-range, 3.47 down to 1.93 for within-range, P omalizumab have significantly improved symptom control, quality of life and lung function to a similar degree to within-range participants, achieved without dose escalation above 750 mg. © 2016 John Wiley & Sons Ltd.

  17. Occupation embedded in a real life: interweaving occupational science and occupational therapy. 1993 Eleanor Clarke Slagle Lecture.

    Science.gov (United States)

    Clark, F

    1993-12-01

    This lecture presents an example of research in the genre of interpretive occupational science and demonstrates how occupational science can inform clinical practice. The innovative qualitative methodology used blended elements of the anthropological tradition of life history ethnography, ethnomethodology, the naturalistic methods used by Mattingly and Schön to study practice, and especially narrative analysis as described by Polkinghorne. The bulk of the paper is presented in the form of a narrative analysis that provides an account of a stroke survivor's personal struggle for recovery, a story that emerged from transcription, coding, and analysis of transcripts from approximately 20 hours of interview time. First, this narrative analysis provides an example of how the occupational science framework can evoke a particular kind of storytelling in which childhood occupation can be related to adult character. Storytelling of this kind is later shown to be therapeutic for the stroke survivor. Next, the narrative illustrates how rehabilitation can be experienced by the survivor as a rite of passage in which a person is moved to disability status and then abandoned. Finally, a picture is given of how occupational story making and occupational storytelling embedded in real life can nurture the human spirit to act and can become the core of clinical practice.

  18. Midlife Family Economic Hardship and Later Life Cardiometabolic Health: The Protective Role of Marital Integration.

    Science.gov (United States)

    Wickrama, Kandauda A S; O'Neal, Catherine Walker; Neppl, Tricia K

    2018-05-25

    The current study assesses the unique influences of family economic hardship (FEH) in early and late midlife on husbands' and wives' body mass index (BMI) and the influence of BMI on the onset of cardiometabolic (CM) disease in later adulthood. The protective role of marital integration is also considered in relation to the stress-response link between FEH and BMI. Analyses were performed using structural equation modeling with prospective data from 257 husbands and wives in enduring marriages over a period of 25 years beginning when they were approximately 40 years old. A multigroup analysis tested the moderating role of marital integration. The distal influence of FEH in early midlife on BMI in later adulthood remained statistically significant even after controlling for proximal FEH. Proximal FEH in later midlife was influential for wives', but not husbands', BMI. BMI in later midlife was related to the onset of CM disease in their later life. Moderation analysis showed that FEH and subsequent BMI were associated for couples with below average levels of behavioral integration but not for couples with above average levels of integration. Taken together, these findings suggest a family-health process stemming from early FEH and operating cumulatively over the life course. FEH in early midlife is a persistent determinant of physiological dysregulation as reflected by BMI. Findings identify BMI as a modifiable leverage point for the long-term reduction of CM disease risk and highlight the role of spouses as a buffer against the detrimental stress-health association.

  19. The Maia Spectroscopy Detector System: Engineering for Integrated Pulse Capture, Low-Latency Scanning and Real-Time Processing

    International Nuclear Information System (INIS)

    Kirkham, R.; Siddons, D.; Dunn, P.A.; Kuczewski, A.J.; Dodanwela, R.; Moorhead, G.F.; Ryan, C.G.; De Geronimo, G.; Beuttenmuller, R.; Pinelli, D.; Pfeffer, M.; Davey, P.; Jensen, M.; de Jonge, M.D.; Howard, D.L.; Kusel, M.; McKinlay, J.

    2010-01-01

    The Maia detector system is engineered for energy dispersive x-ray fluorescence spectroscopy and elemental imaging at photon rates exceeding 10 7 /s, integrated scanning of samples for pixel transit times as small as 50 (micro)s and high definition images of 10 8 pixels and real-time processing of detected events for spectral deconvolution and online display of pure elemental images. The system developed by CSIRO and BNL combines a planar silicon 384 detector array, application-specific integrated circuits for pulse shaping and peak detection and sampling and optical data transmission to an FPGA-based pipelined, parallel processor. This paper describes the system and the underpinning engineering solutions.

  20. Syringe's between the SIDP and structural integrity: assessments of fracture and real time fatigue

    International Nuclear Information System (INIS)

    Cicero, R.; Sierra, M.

    2011-01-01

    Analysis of aging and degradation of the components in nuclear plants is a fundamental requirement nowadays indispensable in the life management of the plants, both to ensure the perfect operation and to ensure the safety of people and the environment, and therefore instrumental in the renewal of the operating license for the same.