WorldWideScience

Sample records for integrated vector management

  1. Integrated vector management for malaria control

    Directory of Open Access Journals (Sweden)

    Impoinvil Daniel E

    2008-12-01

    Full Text Available Abstract Integrated vector management (IVM is defined as "a rational decision-making process for the optimal use of resources for vector control" and includes five key elements: 1 evidence-based decision-making, 2 integrated approaches 3, collaboration within the health sector and with other sectors, 4 advocacy, social mobilization, and legislation, and 5 capacity-building. In 2004, the WHO adopted IVM globally for the control of all vector-borne diseases. Important recent progress has been made in developing and promoting IVM for national malaria control programmes in Africa at a time when successful malaria control programmes are scaling-up with insecticide-treated nets (ITN and/or indoor residual spraying (IRS coverage. While interventions using only ITNs and/or IRS successfully reduce transmission intensity and the burden of malaria in many situations, it is not clear if these interventions alone will achieve those critical low levels that result in malaria elimination. Despite the successful employment of comprehensive integrated malaria control programmes, further strengthening of vector control components through IVM is relevant, especially during the "end-game" where control is successful and further efforts are required to go from low transmission situations to sustained local and country-wide malaria elimination. To meet this need and to ensure sustainability of control efforts, malaria control programmes should strengthen their capacity to use data for decision-making with respect to evaluation of current vector control programmes, employment of additional vector control tools in conjunction with ITN/IRS tactics, case-detection and treatment strategies, and determine how much and what types of vector control and interdisciplinary input are required to achieve malaria elimination. Similarly, on a global scale, there is a need for continued research to identify and evaluate new tools for vector control that can be integrated with

  2. Integrated vector management: the Zambian experience.

    Science.gov (United States)

    Chanda, Emmanuel; Masaninga, Fred; Coleman, Michael; Sikaala, Chadwick; Katebe, Cecilia; Macdonald, Michael; Baboo, Kumar S; Govere, John; Manga, Lucien

    2008-08-27

    The Zambian Malaria Control Programme with the Roll Back Malaria (RBM) partners have developed the current National Malaria Strategic Plan (NMSP 2006-2011) which focuses on prevention based on the Integrated Vector Management (IVM) strategy. The introduction and implementation of an IVM strategy was planned in accordance with the World Health Organization (WHO) steps towards IVM implementation namely Introduction Phase, Consolidation Phase and Expansion Phase. IVM has created commitment for Legal and Regulatory policy review, monitoring, Research and a strong stewardship by the chemical suppliers. It has also leveraged additional resources, improved inter-sectoral collaboration, capacity building and enhanced community participation which facilitated a steady scaling up in coverage and utilisation of key preventive interventions. Thus, markedly reducing malaria incidence and case fatalities in the country. Zambia has successfully introduced, consolidated and expanded IVM activities. Resulting in increased coverage and utilization of interventions and markedly reducing malaria-related morbidity and mortality while ensuring a better protection of the environment.

  3. Integrated vector management: The Zambian experience

    Directory of Open Access Journals (Sweden)

    Katebe Cecilia

    2008-08-01

    Full Text Available Abstract Background The Zambian Malaria Control Programme with the Roll Back Malaria (RBM partners have developed the current National Malaria Strategic Plan (NMSP 2006–2011 which focuses on prevention based on the Integrated Vector Management (IVM strategy. The introduction and implementation of an IVM strategy was planned in accordance with the World Health Organization (WHO steps towards IVM implementation namely Introduction Phase, Consolidation Phase and Expansion Phase. Achievements IVM has created commitment for Legal and Regulatory policy review, monitoring, Research and a strong stewardship by the chemical suppliers. It has also leveraged additional resources, improved inter-sectoral collaboration, capacity building and enhanced community participation which facilitated a steady scaling up in coverage and utilisation of key preventive interventions. Thus, markedly reducing malaria incidence and case fatalities in the country. Conclusion Zambia has successfully introduced, consolidated and expanded IVM activities. Resulting in increased coverage and utilization of interventions and markedly reducing malaria-related morbidity and mortality while ensuring a better protection of the environment.

  4. VECTOR INTEGRATION

    NARCIS (Netherlands)

    Thomas, E. G. F.

    2012-01-01

    This paper deals with the theory of integration of scalar functions with respect to a measure with values in a, not necessarily locally convex, topological vector space. It focuses on the extension of such integrals from bounded measurable functions to the class of integrable functions, proving

  5. Integrating Transgenic Vector Manipulation with Clinical Interventions to Manage Vector-Borne Diseases.

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    Kenichi W Okamoto

    2016-03-01

    Full Text Available Many vector-borne diseases lack effective vaccines and medications, and the limitations of traditional vector control have inspired novel approaches based on using genetic engineering to manipulate vector populations and thereby reduce transmission. Yet both the short- and long-term epidemiological effects of these transgenic strategies are highly uncertain. If neither vaccines, medications, nor transgenic strategies can by themselves suffice for managing vector-borne diseases, integrating these approaches becomes key. Here we develop a framework to evaluate how clinical interventions (i.e., vaccination and medication can be integrated with transgenic vector manipulation strategies to prevent disease invasion and reduce disease incidence. We show that the ability of clinical interventions to accelerate disease suppression can depend on the nature of the transgenic manipulation deployed (e.g., whether vector population reduction or replacement is attempted. We find that making a specific, individual strategy highly effective may not be necessary for attaining public-health objectives, provided suitable combinations can be adopted. However, we show how combining only partially effective antimicrobial drugs or vaccination with transgenic vector manipulations that merely temporarily lower vector competence can amplify disease resurgence following transient suppression. Thus, transgenic vector manipulation that cannot be sustained can have adverse consequences-consequences which ineffective clinical interventions can at best only mitigate, and at worst temporarily exacerbate. This result, which arises from differences between the time scale on which the interventions affect disease dynamics and the time scale of host population dynamics, highlights the importance of accounting for the potential delay in the effects of deploying public health strategies on long-term disease incidence. We find that for systems at the disease-endemic equilibrium, even

  6. How effective is integrated vector management against malaria and lymphatic filariasis where the diseases are transmitted by the same vector?

    OpenAIRE

    Stone, C.; Lindsay, S.W.; Chitnis, N.

    2014-01-01

    Background: The opportunity to integrate vector management across multiple vector-borne diseases is particularly plausible for malaria and lymphatic filariasis (LF) control where both diseases are transmitted by the same vector. To date most examples of integrated control targeting these diseases have been unanticipated consequences of malaria vector control, rather than planned strategies that aim to maximize the efficacy and take the complex ecological and biological interactions between th...

  7. Insecticide resistance in disease vectors from Mayotte: an opportunity for integrated vector management.

    Science.gov (United States)

    Pocquet, Nicolas; Darriet, Frédéric; Zumbo, Betty; Milesi, Pascal; Thiria, Julien; Bernard, Vincent; Toty, Céline; Labbé, Pierrick; Chandre, Fabrice

    2014-07-01

    services. Together with the relative isolation of the island (thus limited immigration of mosquitoes), it provides us with a unique place to implement an integrated vector management plan, including all the good practices learned from previous experiences.

  8. How effective is integrated vector management against malaria and lymphatic filariasis where the diseases are transmitted by the same vector?

    Directory of Open Access Journals (Sweden)

    Christopher M Stone

    2014-12-01

    Full Text Available The opportunity to integrate vector management across multiple vector-borne diseases is particularly plausible for malaria and lymphatic filariasis (LF control where both diseases are transmitted by the same vector. To date most examples of integrated control targeting these diseases have been unanticipated consequences of malaria vector control, rather than planned strategies that aim to maximize the efficacy and take the complex ecological and biological interactions between the two diseases into account.We developed a general model of malaria and LF transmission and derived expressions for the basic reproductive number (R0 for each disease. Transmission of both diseases was most sensitive to vector mortality and biting rate. Simulating different levels of coverage of long lasting-insecticidal nets (LLINs and larval control confirms the effectiveness of these interventions for the control of both diseases. When LF was maintained near the critical density of mosquitoes, minor levels of vector control (8% coverage of LLINs or treatment of 20% of larval sites were sufficient to eliminate the disease. Malaria had a far greater R0 and required a 90% population coverage of LLINs in order to eliminate it. When the mosquito density was doubled, 36% and 58% coverage of LLINs and larval control, respectively, were required for LF elimination; and malaria elimination was possible with a combined coverage of 78% of LLINs and larval control.Despite the low level of vector control required to eliminate LF, simulations suggest that prevalence of LF will decrease at a slower rate than malaria, even at high levels of coverage. If representative of field situations, integrated management should take into account not only how malaria control can facilitate filariasis elimination, but strike a balance between the high levels of coverage of (multiple interventions required for malaria with the long duration predicted to be required for filariasis elimination.

  9. How effective is integrated vector management against malaria and lymphatic filariasis where the diseases are transmitted by the same vector?

    Science.gov (United States)

    Stone, Christopher M; Lindsay, Steve W; Chitnis, Nakul

    2014-12-01

    The opportunity to integrate vector management across multiple vector-borne diseases is particularly plausible for malaria and lymphatic filariasis (LF) control where both diseases are transmitted by the same vector. To date most examples of integrated control targeting these diseases have been unanticipated consequences of malaria vector control, rather than planned strategies that aim to maximize the efficacy and take the complex ecological and biological interactions between the two diseases into account. We developed a general model of malaria and LF transmission and derived expressions for the basic reproductive number (R0) for each disease. Transmission of both diseases was most sensitive to vector mortality and biting rate. Simulating different levels of coverage of long lasting-insecticidal nets (LLINs) and larval control confirms the effectiveness of these interventions for the control of both diseases. When LF was maintained near the critical density of mosquitoes, minor levels of vector control (8% coverage of LLINs or treatment of 20% of larval sites) were sufficient to eliminate the disease. Malaria had a far greater R0 and required a 90% population coverage of LLINs in order to eliminate it. When the mosquito density was doubled, 36% and 58% coverage of LLINs and larval control, respectively, were required for LF elimination; and malaria elimination was possible with a combined coverage of 78% of LLINs and larval control. Despite the low level of vector control required to eliminate LF, simulations suggest that prevalence of LF will decrease at a slower rate than malaria, even at high levels of coverage. If representative of field situations, integrated management should take into account not only how malaria control can facilitate filariasis elimination, but strike a balance between the high levels of coverage of (multiple) interventions required for malaria with the long duration predicted to be required for filariasis elimination.

  10. Consolidating strategic planning and operational frameworks for integrated vector management in Eritrea.

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    Chanda, Emmanuel; Ameneshewa, Birkinesh; Mihreteab, Selam; Berhane, Araia; Zehaie, Assefash; Ghebrat, Yohannes; Usman, Abdulmumini

    2015-12-02

    Contemporary malaria vector control relies on the use of insecticide-based, indoor residual spraying (IRS) and long-lasting insecticidal nets (LLINs). However, malaria-endemic countries, including Eritrea, have struggled to effectively deploy these tools due technical and operational challenges, including the selection of insecticide resistance in malaria vectors. This manuscript outlines the processes undertaken in consolidating strategic planning and operational frameworks for vector control to expedite malaria elimination in Eritrea. The effort to strengthen strategic frameworks for vector control in Eritrea was the 'case' for this study. The integrated vector management (IVM) strategy was developed in 2010 but was not well executed, resulting in a rise in malaria transmission, prompting a process to redefine and relaunch the IVM strategy with integration of other vector borne diseases (VBDs) as the focus. The information sources for this study included all available data and accessible archived documentary records on malaria vector control in Eritrea. Structured literature searches of published, peer-reviewed sources using online, scientific, bibliographic databases, Google Scholar, PubMed and WHO, and a combination of search terms were utilized to gather data. The literature was reviewed and adapted to the local context and translated into the consolidated strategic framework. In Eritrea, communities are grappling with the challenge of VBDs posing public health concerns, including malaria. The global fund financed the scale-up of IRS and LLIN programmes in 2014. Eritrea is transitioning towards malaria elimination and strategic frameworks for vector control have been consolidated by: developing an integrated vector management (IVM) strategy (2015-2019); updating IRS and larval source management (LSM) guidelines; developing training manuals for IRS and LSM; training of national staff in malaria entomology and vector control, including insecticide resistance

  11. Converging Human and Malaria Vector Diagnostics with Data Management towards an Integrated Holistic One Health Approach

    Directory of Open Access Journals (Sweden)

    Konstantinos Mitsakakis

    2018-02-01

    Full Text Available Monitoring malaria prevalence in humans, as well as vector populations, for the presence of Plasmodium, is an integral component of effective malaria control, and eventually, elimination. In the field of human diagnostics, a major challenge is the ability to define, precisely, the causative agent of fever, thereby differentiating among several candidate (also non-malaria febrile diseases. This requires genetic-based pathogen identification and multiplexed analysis, which, in combination, are hardly provided by the current gold standard diagnostic tools. In the field of vectors, an essential component of control programs is the detection of Plasmodium species within its mosquito vectors, particularly in the salivary glands, where the infective sporozoites reside. In addition, the identification of species composition and insecticide resistance alleles within vector populations is a primary task in routine monitoring activities, aiming to support control efforts. In this context, the use of converging diagnostics is highly desirable for providing comprehensive information, including differential fever diagnosis in humans, and mosquito species composition, infection status, and resistance to insecticides of vectors. Nevertheless, the two fields of human diagnostics and vector control are rarely combined, both at the diagnostic and at the data management end, resulting in fragmented data and mis- or non-communication between various stakeholders. To this direction, molecular technologies, their integration in automated platforms, and the co-assessment of data from multiple diagnostic sources through information and communication technologies are possible pathways towards a unified human vector approach.

  12. Converging Human and Malaria Vector Diagnostics with Data Management towards an Integrated Holistic One Health Approach.

    Science.gov (United States)

    Mitsakakis, Konstantinos; Hin, Sebastian; Müller, Pie; Wipf, Nadja; Thomsen, Edward; Coleman, Michael; Zengerle, Roland; Vontas, John; Mavridis, Konstantinos

    2018-02-03

    Monitoring malaria prevalence in humans, as well as vector populations, for the presence of Plasmodium , is an integral component of effective malaria control, and eventually, elimination. In the field of human diagnostics, a major challenge is the ability to define, precisely, the causative agent of fever, thereby differentiating among several candidate (also non-malaria) febrile diseases. This requires genetic-based pathogen identification and multiplexed analysis, which, in combination, are hardly provided by the current gold standard diagnostic tools. In the field of vectors, an essential component of control programs is the detection of Plasmodium species within its mosquito vectors, particularly in the salivary glands, where the infective sporozoites reside. In addition, the identification of species composition and insecticide resistance alleles within vector populations is a primary task in routine monitoring activities, aiming to support control efforts. In this context, the use of converging diagnostics is highly desirable for providing comprehensive information, including differential fever diagnosis in humans, and mosquito species composition, infection status, and resistance to insecticides of vectors. Nevertheless, the two fields of human diagnostics and vector control are rarely combined, both at the diagnostic and at the data management end, resulting in fragmented data and mis- or non-communication between various stakeholders. To this direction, molecular technologies, their integration in automated platforms, and the co-assessment of data from multiple diagnostic sources through information and communication technologies are possible pathways towards a unified human vector approach.

  13. Converging Human and Malaria Vector Diagnostics with Data Management towards an Integrated Holistic One Health Approach

    Science.gov (United States)

    Mitsakakis, Konstantinos; Hin, Sebastian; Wipf, Nadja; Coleman, Michael; Zengerle, Roland; Vontas, John; Mavridis, Konstantinos

    2018-01-01

    Monitoring malaria prevalence in humans, as well as vector populations, for the presence of Plasmodium, is an integral component of effective malaria control, and eventually, elimination. In the field of human diagnostics, a major challenge is the ability to define, precisely, the causative agent of fever, thereby differentiating among several candidate (also non-malaria) febrile diseases. This requires genetic-based pathogen identification and multiplexed analysis, which, in combination, are hardly provided by the current gold standard diagnostic tools. In the field of vectors, an essential component of control programs is the detection of Plasmodium species within its mosquito vectors, particularly in the salivary glands, where the infective sporozoites reside. In addition, the identification of species composition and insecticide resistance alleles within vector populations is a primary task in routine monitoring activities, aiming to support control efforts. In this context, the use of converging diagnostics is highly desirable for providing comprehensive information, including differential fever diagnosis in humans, and mosquito species composition, infection status, and resistance to insecticides of vectors. Nevertheless, the two fields of human diagnostics and vector control are rarely combined, both at the diagnostic and at the data management end, resulting in fragmented data and mis- or non-communication between various stakeholders. To this direction, molecular technologies, their integration in automated platforms, and the co-assessment of data from multiple diagnostic sources through information and communication technologies are possible pathways towards a unified human vector approach. PMID:29401670

  14. Consolidating tactical planning and implementation frameworks for integrated vector management in Uganda.

    Science.gov (United States)

    Okia, Michael; Okui, Peter; Lugemwa, Myers; Govere, John M; Katamba, Vincent; Rwakimari, John B; Mpeka, Betty; Chanda, Emmanuel

    2016-04-14

    Integrated vector management (IVM) is the recommended approach for controlling some vector-borne diseases (VBD). In the face of current challenges to disease vector control, IVM is vital to achieve national targets set for VBD control. Though global efforts, especially for combating malaria, now focus on elimination and eradication, IVM remains useful for Uganda which is principally still in the control phase of the malaria continuum. This paper outlines the processes undertaken to consolidate tactical planning and implementation frameworks for IVM in Uganda. The Uganda National Malaria Control Programme with its efforts to implement an IVM approach to vector control was the 'case' for this study. Integrated management of malaria vectors in Uganda remained an underdeveloped component of malaria control policy. In 2012, knowledge and perceptions of malaria vector control policy and IVM were assessed, and recommendations for a specific IVM policy were made. In 2014, a thorough vector control needs assessment (VCNA) was conducted according to WHO recommendations. The findings of the VCNA informed the development of the national IVM strategic guidelines. Information sources for this study included all available data and accessible archived documentary records on VBD control in Uganda. The literature was reviewed and adapted to the local context and translated into the consolidated tactical framework. WHO recommends implementation of IVM as the main strategy to vector control and has encouraged member states to adopt the approach. However, many VBD-endemic countries lack IVM policy frameworks to guide implementation of the approach. In Uganda most VBD coexists and could be managed more effectively if done in tandem. In order to successfully control malaria and other VBD and move towards their elimination, the country needs to scale up proven and effective vector control interventions and also learn from the experience of other countries. The IVM strategy is important in

  15. Integrated Storage and Management of Vector and Raster Data Based on Oracle Database

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    WU Zheng

    2017-05-01

    Full Text Available At present, there are many problems in the storage and management of multi-source heterogeneous spatial data, such as the difficulty of transferring, the lack of unified storage and the low efficiency. By combining relational database and spatial data engine technology, an approach for integrated storage and management of vector and raster data is proposed on the basis of Oracle in this paper. This approach establishes an integrated storage model on vector and raster data and optimizes the retrieval mechanism at first, then designs a framework for the seamless data transfer, finally realizes the unified storage and efficient management of multi-source heterogeneous data. By comparing experimental results with the international leading similar software ArcSDE, it is proved that the proposed approach has higher data transfer performance and better query retrieval efficiency.

  16. Reducing vector-borne disease by empowering farmers in integrated vector management

    NARCIS (Netherlands)

    Berg, van den H.; Hildebrand, von A.; Ragunathan, V.; Das, P.K.

    2007-01-01

    PROBLEM: Irrigated agriculture exposes rural people to health risks associated with vector-borne diseases and pesticides used in agriculture and for public health protection. Most developing countries lack collaboration between the agricultural and health sectors to jointly address these problems.

  17. Sesquilinear uniform vector integral

    Indian Academy of Sciences (India)

    theory, together with his integral, dominate contemporary mathematics. ... directions belonging to Bartle and Dinculeanu (see [1], [6], [7] and [2]). ... in this manner, namely he integrated vector functions with respect to measures of bounded.

  18. Vector control programs in Saint Johns County, Florida and Guayas, Ecuador: successes and barriers to integrated vector management.

    Science.gov (United States)

    Naranjo, Diana P; Qualls, Whitney A; Jurado, Hugo; Perez, Juan C; Xue, Rui-De; Gomez, Eduardo; Beier, John C

    2014-07-02

    Vector-borne diseases (VBDs) and mosquito control programs (MCPs) diverge in settings and countries, and lead control specialists need to be aware of the most effective control strategies. Integrated Vector Management (IVM) strategies, once implemented in MCPs, aim to reduce cost and optimize protection of the populations against VBDs. This study presents a strengths, weaknesses, opportunities, and threats (SWOT) analysis to compare IVM strategies used by MCPs in Saint Johns County, Florida and Guayas, Ecuador. This research evaluates MCPs strategies to improve vector control activities. Methods included descriptive findings of the MCP operations. Information was obtained from vector control specialists, directors, and residents through field trips, surveys, and questionnaires. Evaluations of the strategies and assets of the control programs where obtained through SWOT analysis and within an IVM approach. Organizationally, the Floridian MCP is a tax-based District able to make decisions independently from county government officials, with the oversight of an elected board of commissioners. The Guayas program is directed by the country government and assessed by non-governmental organizations like the World health Organization. Operationally, the Floridian MCP conducts entomological surveillance and the Ecuadorian MCP focuses on epidemiological monitoring of human disease cases. Strengths of both MCPs were their community participation and educational programs. Weaknesses for both MCPs included limitations in budgets and technical capabilities. Opportunities, for both MCPs, are additional funding and partnerships with private, non-governmental, and governmental organizations. Threats experienced by both MCPs included political constraints and changes in the social and ecological environment that affect mosquito densities and control efforts. IVM pillars for policy making were used to compare the information among the programs. Differences included how the Ecuadorian

  19. Vector control programs in Saint Johns County, Florida and Guayas, Ecuador: successes and barriers to integrated vector management

    Science.gov (United States)

    2014-01-01

    Background Vector-borne diseases (VBDs) and mosquito control programs (MCPs) diverge in settings and countries, and lead control specialists need to be aware of the most effective control strategies. Integrated Vector Management (IVM) strategies, once implemented in MCPs, aim to reduce cost and optimize protection of the populations against VBDs. This study presents a strengths, weaknesses, opportunities, and threats (SWOT) analysis to compare IVM strategies used by MCPs in Saint Johns County, Florida and Guayas, Ecuador. This research evaluates MCPs strategies to improve vector control activities. Methods Methods included descriptive findings of the MCP operations. Information was obtained from vector control specialists, directors, and residents through field trips, surveys, and questionnaires. Evaluations of the strategies and assets of the control programs where obtained through SWOT analysis and within an IVM approach. Results Organizationally, the Floridian MCP is a tax-based District able to make decisions independently from county government officials, with the oversight of an elected board of commissioners. The Guayas program is directed by the country government and assessed by non-governmental organizations like the World health Organization. Operationally, the Floridian MCP conducts entomological surveillance and the Ecuadorian MCP focuses on epidemiological monitoring of human disease cases. Strengths of both MCPs were their community participation and educational programs. Weaknesses for both MCPs included limitations in budgets and technical capabilities. Opportunities, for both MCPs, are additional funding and partnerships with private, non-governmental, and governmental organizations. Threats experienced by both MCPs included political constraints and changes in the social and ecological environment that affect mosquito densities and control efforts. IVM pillars for policy making were used to compare the information among the programs. Differences

  20. Integrated pest management and allocation of control efforts for vector-borne diseases

    Science.gov (United States)

    Ginsberg, H.S.

    2001-01-01

    Applications of various control methods were evaluated to determine how to integrate methods so as to minimize the number of human cases of vector-borne diseases. These diseases can be controlled by lowering the number of vector-human contacts (e.g., by pesticide applications or use of repellents), or by lowering the proportion of vectors infected with pathogens (e.g., by lowering or vaccinating reservoir host populations). Control methods should be combined in such a way as to most efficiently lower the probability of human encounter with an infected vector. Simulations using a simple probabilistic model of pathogen transmission suggest that the most efficient way to integrate different control methods is to combine methods that have the same effect (e.g., combine treatments that lower the vector population; or combine treatments that lower pathogen prevalence in vectors). Combining techniques that have different effects (e.g., a technique that lowers vector populations with a technique that lowers pathogen prevalence in vectors) will be less efficient than combining two techniques that both lower vector populations or combining two techniques that both lower pathogen prevalence, costs being the same. Costs of alternative control methods generally differ, so the efficiency of various combinations at lowering human contact with infected vectors should be estimated at available funding levels. Data should be collected from initial trials to improve the effects of subsequent interventions on the number of human cases.

  1. Integrating natural and social sciences to manage sustainably vectors of change in the marine environment: Dogger Bank transnational case study

    Science.gov (United States)

    Burdon, Daryl; Boyes, Suzanne J.; Elliott, Michael; Smyth, Katie; Atkins, Jonathan P.; Barnes, Richard A.; Wurzel, Rüdiger K.

    2018-02-01

    The management of marine resources is a complex process driven by the dynamics of the natural system and the influence of stakeholders including policy-makers. An integration of natural and social sciences research is required by policy-makers to better understand, and manage sustainably, natural changes and anthropogenic activities within particular marine systems. Given the uncertain development of activities in the marine environment, future scenarios assessments can be used to investigate whether marine policy measures are robust and sustainable. This paper develops an interdisciplinary framework, which incorporates future scenarios assessments, and identifies four main types of evaluation needed to integrate natural and social sciences research to support the integrated management of the marine environment: environmental policy and governance assessments; ecosystem services, indicators and valuation; modelling tools for management evaluations, and risk assessment and risk management. The importance of stakeholder engagement within each evaluation method is highlighted. The paper focuses on the transnational spatial marine management of the Dogger Bank, in the central North Sea, a site which is very important ecologically, economically and politically. Current management practices are reviewed, and research tools to support future management decisions are applied and discussed in relation to two main vectors of change affecting the Dogger Bank, namely commercial fisheries and offshore wind farm developments, and in relation to the need for nature conservation. The input of local knowledge through stakeholder engagement is highlighted as a necessary requirement to produce site-specific policy recommendations for the future management of the Dogger Bank. We present wider policy recommendations to integrate natural and social sciences in a global marine context.

  2. Projected economic losses due to vector and vector-borne parasitic diseases in livestock of India and its significance in implementing the concept of integrated practices for vector management

    Directory of Open Access Journals (Sweden)

    B. W. Narladkar

    2018-02-01

    Full Text Available Broadly, species of arthropods infesting livestock are grouped into flies (biting and non-biting, fleas, lice (biting and sucking, ticks (soft and hard, and mites (burrowing, non-burrowing, and follicular. Among which, biting and non-biting flies and ticks are the potent vectors for many bacterial, viral, rickettsial, and protozoan diseases. Vectors of livestock are having economic significance on three points (1 direct losses from their bite and annoyance, worries, and psychological disturbances produced during the act of biting and feeding, (2 diseases they transmit, and (3 expenditure incurred for their control. Flies such as Culicoides spp. and Musca spp. and various species of hard ticks play important role in disease transmission in addition to their direct effects. For control of vectors, recent concept of integrated pest management (IPM provides the best solution and also addresses the problems related to acaricide resistance and environmental protection from hazardous chemicals. However, to successfully implement the concept of IPM, for each vector species, estimation of two monitory benchmarks, i.e., economic injury level (EIL and economic threshold level (ETL is essential prerequisite. For many vector species and under several circumstances, estimation of EIL and ETL appears to be difficult. Under such scenario, although may not be exact, an approximate estimate can be accrued by taking into account several criteria such as percent prevalence of vectors in a geographical area, percent losses produced, total livestock population, and current prices of livestock products such as milk, meat, and wool. Method for approximate estimation is first time described and elaborated in the present review article.

  3. Projected economic losses due to vector and vector-borne parasitic diseases in livestock of India and its significance in implementing the concept of integrated practices for vector management

    Science.gov (United States)

    Narladkar, B. W.

    2018-01-01

    Broadly, species of arthropods infesting livestock are grouped into flies (biting and non-biting), fleas, lice (biting and sucking), ticks (soft and hard), and mites (burrowing, non-burrowing, and follicular). Among which, biting and non-biting flies and ticks are the potent vectors for many bacterial, viral, rickettsial, and protozoan diseases. Vectors of livestock are having economic significance on three points (1) direct losses from their bite and annoyance, worries, and psychological disturbances produced during the act of biting and feeding, (2) diseases they transmit, and (3) expenditure incurred for their control. Flies such as Culicoides spp. and Musca spp. and various species of hard ticks play important role in disease transmission in addition to their direct effects. For control of vectors, recent concept of integrated pest management (IPM) provides the best solution and also addresses the problems related to acaricide resistance and environmental protection from hazardous chemicals. However, to successfully implement the concept of IPM, for each vector species, estimation of two monitory benchmarks, i.e., economic injury level (EIL) and economic threshold level (ETL) is essential prerequisite. For many vector species and under several circumstances, estimation of EIL and ETL appears to be difficult. Under such scenario, although may not be exact, an approximate estimate can be accrued by taking into account several criteria such as percent prevalence of vectors in a geographical area, percent losses produced, total livestock population, and current prices of livestock products such as milk, meat, and wool. Method for approximate estimation is first time described and elaborated in the present review article. PMID:29657396

  4. Optimization of the Aedes aegypti Control Strategies for Integrated Vector Management

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    Marat Rafikov

    2015-01-01

    Full Text Available We formulate an infinite-time quadratic functional minimization problem of Aedes aegypti mosquito population. Three techniques of mosquito population management, chemical insecticide control, sterile insect technique control, and environmental carrying capacity reduction, are combined in order to obtain the most sustainable strategy to reduce mosquito population and consequently dengue disease. The solution of the optimization control problem is based on the ideas of the Dynamic Programming and Lyapunov Stability using State-Dependent Riccati Equation (SDRE control method. Different scenarios are analyzed combining three mentioned population management efforts in order to assess the most sustainable policy to reduce the mosquito population.

  5. Geostatistical evaluation of integrated marsh management impact on mosquito vectors using before-after-control-impact (BACI design

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    Dempsey Mary E

    2009-06-01

    Full Text Available Abstract Background In many parts of the world, salt marshes play a key ecological role as the interface between the marine and the terrestrial environments. Salt marshes are also exceedingly important for public health as larval habitat for mosquitoes that are vectors of disease and significant biting pests. Although grid ditching and pesticides have been effective in salt marsh mosquito control, marsh degradation and other environmental considerations compel a different approach. Targeted habitat modification and biological control methods known as Open Marsh Water Management (OMWM had been proposed as a viable alternative to marsh-wide physical alterations and chemical control. However, traditional larval sampling techniques may not adequately assess the impacts of marsh management on mosquito larvae. To assess the effectiveness of integrated OMWM and marsh restoration techniques for mosquito control, we analyzed the results of a 5-year OMWM/marsh restoration project to determine changes in mosquito larval production using GIS and geostatistical methods. Methods The following parameters were evaluated using "Before-After-Control-Impact" (BACI design: frequency and geographic extent of larval production, intensity of larval production, changes in larval habitat, and number of larvicide applications. The analyses were performed using Moran's I, Getis-Ord, and Spatial Scan statistics on aggregated before and after data as well as data collected over time. This allowed comparison of control and treatment areas to identify changes attributable to the OMWM/marsh restoration modifications. Results The frequency of finding mosquito larvae in the treatment areas was reduced by 70% resulting in a loss of spatial larval clusters compared to those found in the control areas. This effect was observed directly following OMWM treatment and remained significant throughout the study period. The greatly reduced frequency of finding larvae in the treatment

  6. Geostatistical evaluation of integrated marsh management impact on mosquito vectors using before-after-control-impact (BACI) design.

    Science.gov (United States)

    Rochlin, Ilia; Iwanejko, Tom; Dempsey, Mary E; Ninivaggi, Dominick V

    2009-06-23

    In many parts of the world, salt marshes play a key ecological role as the interface between the marine and the terrestrial environments. Salt marshes are also exceedingly important for public health as larval habitat for mosquitoes that are vectors of disease and significant biting pests. Although grid ditching and pesticides have been effective in salt marsh mosquito control, marsh degradation and other environmental considerations compel a different approach. Targeted habitat modification and biological control methods known as Open Marsh Water Management (OMWM) had been proposed as a viable alternative to marsh-wide physical alterations and chemical control. However, traditional larval sampling techniques may not adequately assess the impacts of marsh management on mosquito larvae. To assess the effectiveness of integrated OMWM and marsh restoration techniques for mosquito control, we analyzed the results of a 5-year OMWM/marsh restoration project to determine changes in mosquito larval production using GIS and geostatistical methods. The following parameters were evaluated using "Before-After-Control-Impact" (BACI) design: frequency and geographic extent of larval production, intensity of larval production, changes in larval habitat, and number of larvicide applications. The analyses were performed using Moran's I, Getis-Ord, and Spatial Scan statistics on aggregated before and after data as well as data collected over time. This allowed comparison of control and treatment areas to identify changes attributable to the OMWM/marsh restoration modifications. The frequency of finding mosquito larvae in the treatment areas was reduced by 70% resulting in a loss of spatial larval clusters compared to those found in the control areas. This effect was observed directly following OMWM treatment and remained significant throughout the study period. The greatly reduced frequency of finding larvae in the treatment areas led to a significant decrease (approximately 44%) in

  7. Horizontal vectorization of electron repulsion integrals.

    Science.gov (United States)

    Pritchard, Benjamin P; Chow, Edmond

    2016-10-30

    We present an efficient implementation of the Obara-Saika algorithm for the computation of electron repulsion integrals that utilizes vector intrinsics to calculate several primitive integrals concurrently in a SIMD vector. Initial benchmarks display a 2-4 times speedup with AVX instructions over comparable scalar code, depending on the basis set. Speedup over scalar code is found to be sensitive to the level of contraction of the basis set, and is best for (lAlB|lClD) quartets when lD  = 0 or lB=lD=0, which makes such a vectorization scheme particularly suitable for density fitting. The basic Obara-Saika algorithm, how it is vectorized, and the performance bottlenecks are analyzed and discussed. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  8. Integrated optic vector-matrix multiplier

    Science.gov (United States)

    Watts, Michael R [Albuquerque, NM

    2011-09-27

    A vector-matrix multiplier is disclosed which uses N different wavelengths of light that are modulated with amplitudes representing elements of an N.times.1 vector and combined to form an input wavelength-division multiplexed (WDM) light stream. The input WDM light stream is split into N streamlets from which each wavelength of the light is individually coupled out and modulated for a second time using an input signal representing elements of an M.times.N matrix, and is then coupled into an output waveguide for each streamlet to form an output WDM light stream which is detected to generate a product of the vector and matrix. The vector-matrix multiplier can be formed as an integrated optical circuit using either waveguide amplitude modulators or ring resonator amplitude modulators.

  9. The Integration Order of Vector Autoregressive Processes

    DEFF Research Database (Denmark)

    Franchi, Massimo

    We show that the order of integration of a vector autoregressive process is equal to the difference between the multiplicity of the unit root in the characteristic equation and the multiplicity of the unit root in the adjoint matrix polynomial. The equivalence with the standard I(1) and I(2...

  10. Geostatistical evaluation of integrated marsh management impact on mosquito vectors using before-after-control-impact (BACI) design

    OpenAIRE

    Rochlin, Ilia; Iwanejko, Tom; Dempsey, Mary E; Ninivaggi, Dominick V

    2009-01-01

    Abstract Background In many parts of the world, salt marshes play a key ecological role as the interface between the marine and the terrestrial environments. Salt marshes are also exceedingly important for public health as larval habitat for mosquitoes that are vectors of disease and significant biting pests. Although grid ditching and pesticides have been effective in salt marsh mosquito control, marsh degradation and other environmental considerations compel a different approach. Targeted h...

  11. Investigation of Optimal Integrated Circuit Raster Image Vectorization Method

    Directory of Open Access Journals (Sweden)

    Leonas Jasevičius

    2011-03-01

    Full Text Available Visual analysis of integrated circuit layer requires raster image vectorization stage to extract layer topology data to CAD tools. In this paper vectorization problems of raster IC layer images are presented. Various line extraction from raster images algorithms and their properties are discussed. Optimal raster image vectorization method was developed which allows utilization of common vectorization algorithms to achieve the best possible extracted vector data match with perfect manual vectorization results. To develop the optimal method, vectorized data quality dependence on initial raster image skeleton filter selection was assessed.Article in Lithuanian

  12. Design and Potential of Non-Integrating Lentiviral Vectors

    Directory of Open Access Journals (Sweden)

    Aaron Shaw

    2014-01-01

    Full Text Available Lentiviral vectors have demonstrated promising results in clinical trials that target cells of the hematopoietic system. For these applications, they are the vectors of choice since they provide stable integration into cells that will undergo extensive expansion in vivo. Unfortunately, integration can have unintended consequences including dysregulated cell growth. Therefore, lentiviral vectors that do not integrate are predicted to have a safer profile compared to integrating vectors and should be considered for applications where transient expression is required or for sustained episomal expression such as in quiescent cells. In this review, the system for generating lentiviral vectors will be described and used to illustrate how alterations in the viral integrase or vector Long Terminal Repeats have been used to generate vectors that lack the ability to integrate. In addition to their safety advantages, these non-integrating lentiviral vectors can be used when persistent expression would have adverse consequences. Vectors are currently in development for use in vaccinations, cancer therapy, site-directed gene insertions, gene disruption strategies, and cell reprogramming. Preclinical work will be described that illustrates the potential of this unique vector system in human gene therapy.

  13. Integrated management systems

    CERN Document Server

    Bugdol, Marek

    2015-01-01

    Examining the challenges of integrated management, this book explores the importance and potential benefits of using an integrated approach as a cross-functional concept of management. It covers not only standardized management systems (e.g. International Organization for Standardization), but also models of self-assessment, as well as different types of integration. Furthermore, it demonstrates how processes and systems can be integrated, and how management efficiency can be increased. The major part of this book focuses on management concepts which use integration as a key tool of management processes (e.g. the systematic approach, supply chain management, virtual and network organizations, processes management and total quality management). Case studies, illustrations, and tables are also provided to exemplify and illuminate the content, as well as examples of successful and failed integrations. Providing a particularly useful resource to managers and specialists involved in the improvement of organization...

  14. Integrated nursery pest management

    Science.gov (United States)

    R. Kasten Dumroese

    2012-01-01

    What is integrated pest management? Take a look at the definition of each word to better understand the concept. Two of the words (integrated and management) are relatively straightforward. Integrated means to blend pieces or concepts into a unified whole, and management is the wise use of techniques to successfully accomplish a desired outcome. A pest is any biotic (...

  15. SAM: Support Vector Machine Based Active Queue Management

    International Nuclear Information System (INIS)

    Shah, M.S.

    2014-01-01

    Recent years have seen an increasing interest in the design of AQM (Active Queue Management) controllers. The purpose of these controllers is to manage the network congestion under varying loads, link delays and bandwidth. In this paper, a new AQM controller is proposed which is trained by using the SVM (Support Vector Machine) with the RBF (Radial Basis Function) kernal. The proposed controller is called the support vector based AQM (SAM) controller. The performance of the proposed controller has been compared with three conventional AQM controllers, namely the Random Early Detection, Blue and Proportional Plus Integral Controller. The preliminary simulation studies show that the performance of the proposed controller is comparable to the conventional controllers. However, the proposed controller is more efficient in controlling the queue size than the conventional controllers. (author)

  16. Enhancers Are Major Targets for Murine Leukemia Virus Vector Integration

    Science.gov (United States)

    De Ravin, Suk See; Su, Ling; Theobald, Narda; Choi, Uimook; Macpherson, Janet L.; Poidinger, Michael; Symonds, Geoff; Pond, Susan M.; Ferris, Andrea L.; Hughes, Stephen H.

    2014-01-01

    ABSTRACT Retroviral vectors have been used in successful gene therapies. However, in some patients, insertional mutagenesis led to leukemia or myelodysplasia. Both the strong promoter/enhancer elements in the long terminal repeats (LTRs) of murine leukemia virus (MLV)-based vectors and the vector-specific integration site preferences played an important role in these adverse clinical events. MLV integration is known to prefer regions in or near transcription start sites (TSS). Recently, BET family proteins were shown to be the major cellular proteins responsible for targeting MLV integration. Although MLV integration sites are significantly enriched at TSS, only a small fraction of the MLV integration sites (integration map of more than one million integration sites from CD34+ hematopoietic stem cells transduced with a clinically relevant MLV-based vector. The integration sites form ∼60,000 tight clusters. These clusters comprise ∼1.9% of the genome. The vast majority (87%) of the integration sites are located within histone H3K4me1 islands, a hallmark of enhancers. The majority of these clusters also have H3K27ac histone modifications, which mark active enhancers. The enhancers of some oncogenes, including LMO2, are highly preferred targets for integration without in vivo selection. IMPORTANCE We show that active enhancer regions are the major targets for MLV integration; this means that MLV preferentially integrates in regions that are favorable for viral gene expression in a variety of cell types. The results provide insights for MLV integration target site selection and also explain the high risk of insertional mutagenesis that is associated with gene therapy trials using MLV vectors. PMID:24501411

  17. Defect-vectors and path integrals in fracture mechanics

    International Nuclear Information System (INIS)

    Roche, R.L.

    1979-01-01

    It seems necessary to introduce the J integral without hypothesis on material behavior. The aim of this paper is this introduction and its consequences. Successively are presented: introduction to defect-vectors and defect-momentum, definition of J(K) and J(L) integrals, equilibrium and energy momentum tensor, energetic signification of the path J and L integrals, and local aspects of the criteria based on path integrals [fr

  18. A Note on the First Integrals of Vector Fields with Integrating Factors and Normalizers

    Directory of Open Access Journals (Sweden)

    Jaume Llibre

    2012-06-01

    Full Text Available We prove a sufficient condition for the existence of explicit first integrals for vector fields which admit an integrating factor. This theorem recovers and extends previous results in the literature on the integrability of vector fields which are volume preserving and possess nontrivial normalizers. Our approach is geometric and coordinate-free and hence it works on any smooth orientable manifold.

  19. Pipeline integrity management

    Energy Technology Data Exchange (ETDEWEB)

    Guyt, J.; Macara, C.

    1997-12-31

    This paper focuses on some of the issues necessary for pipeline operators to consider when addressing the challenge of managing the integrity of their systems. Topics are: Definition; business justification; creation and safeguarding of technical integrity; control and deviation from technical integrity; pipelines; pipeline failure assessment; pipeline integrity assessment; leak detection; emergency response. 6 figs., 3 tabs.

  20. Some BMO estimates for vector-valued multilinear singular integral ...

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    the multilinear operator related to some singular integral operators is obtained. The main purpose of this paper is to establish the BMO end-point estimates for some vector-valued multilinear operators related to certain singular integral operators. First, let us introduce some notations [10,16]. Throughout this paper, Q = Q(x,r).

  1. Invariant hyperplanes and Darboux integrability of polynomial vector fields

    International Nuclear Information System (INIS)

    Zhang Xiang

    2002-01-01

    This paper is composed of two parts. In the first part, we provide an upper bound for the number of invariant hyperplanes of the polynomial vector fields in n variables. This result generalizes those given in Artes et al (1998 Pac. J. Math. 184 207-30) and Llibre and Rodriguez (2000 Bull. Sci. Math. 124 599-619). The second part gives an extension of the Darboux theory of integrability to polynomial vector fields on algebraic varieties

  2. Visualizing Vector Fields Using Line Integral Convolution and Dye Advection

    Science.gov (United States)

    Shen, Han-Wei; Johnson, Christopher R.; Ma, Kwan-Liu

    1996-01-01

    We present local and global techniques to visualize three-dimensional vector field data. Using the Line Integral Convolution (LIC) method to image the global vector field, our new algorithm allows the user to introduce colored 'dye' into the vector field to highlight local flow features. A fast algorithm is proposed that quickly recomputes the dyed LIC images. In addition, we introduce volume rendering methods that can map the LIC texture on any contour surface and/or translucent region defined by additional scalar quantities, and can follow the advection of colored dye throughout the volume.

  3. Defect vectors and path integrals in fracture mechanics

    International Nuclear Information System (INIS)

    Roche, R.L.

    1979-01-01

    Several criteria have been proposed in Elastic Plastic Fracture Mechanics. One of the most interesting ones is the J 1 criterion where J 1 is a path integral surrounding the crack tip. Other path integrals (or surface integrals in 3D problems) can be used. But all these integrals are introduced on an elastic basis, though they are applied in plasticity. This paper shows that it is possible to introduce these integrals without any reference to the elastic behavior of the material. The method is based on the 'defect vector theory' which is an extension of the energy-momentum tensor theory. (orig.)

  4. Experimental Evaluation of Integral Transformations for Engineering Drawings Vectorization

    Directory of Open Access Journals (Sweden)

    Vaský Jozef

    2014-12-01

    Full Text Available The concept of digital manufacturing supposes application of digital technologies in the whole product life cycle. Direct digital manufacturing includes such information technology processes, where products are directly manufactured from 3D CAD model. In digital manufacturing, engineering drawing is replaced by CAD product model. In the contemporary practice, lots of engineering paper-based drawings are still archived. They could be digitalized by scanner and stored to one of the raster graphics format and after that vectorized for interactive editing in the specific software system for technical drawing or for archiving in some of the standard vector graphics file format. The vector format is suitable for 3D model generating, too.The article deals with using of selected integral transformations (Fourier, Hough in the phase of digitalized raster engineering drawings vectorization.

  5. Computation of Surface Integrals of Curl Vector Fields

    Science.gov (United States)

    Hu, Chenglie

    2007-01-01

    This article presents a way of computing a surface integral when the vector field of the integrand is a curl field. Presented in some advanced calculus textbooks such as [1], the technique, as the author experienced, is simple and applicable. The computation is based on Stokes' theorem in 3-space calculus, and thus provides not only a means to…

  6. Classification Method in Integrated Information Network Using Vector Image Comparison

    Directory of Open Access Journals (Sweden)

    Zhou Yuan

    2014-05-01

    Full Text Available Wireless Integrated Information Network (WMN consists of integrated information that can get data from its surrounding, such as image, voice. To transmit information, large resource is required which decreases the service time of the network. In this paper we present a Classification Approach based on Vector Image Comparison (VIC for WMN that improve the service time of the network. The available methods for sub-region selection and conversion are also proposed.

  7. Managing for Organizational Integrity.

    Science.gov (United States)

    Paine, Lynn Sharp

    1994-01-01

    Compliance-based ethics programs focus on prevention, detection, and punishment. Companies should adopt an integrity-based approach to ethics management that combines a concern for the law with an emphasis on managerial responsibility for ethical behavior. (JOW)

  8. Integrated Health Management Definitions

    Data.gov (United States)

    National Aeronautics and Space Administration — The Joint Army Navy NASA Air Force Modeling and Simulation Subcommittee's Integrated Health Management panel was started about 6 years ago to help foster...

  9. Environmental management: a re-emerging vector control strategy.

    Science.gov (United States)

    Ault, S K

    1994-01-01

    Vector control may be accomplished by environmental management (EM), which consists of permanent or long-term modification of the environment, temporary or seasonal manipulation of the environment, and modifying or changing our life styles and practices to reduce human contact with infective vectors. The primary focus of this paper is EM in the control of human malaria, filariasis, arboviruses, Chagas' disease, and schistosomiasis. Modern EM developed as a discipline based primarily in ecologic principles and lessons learned from the adverse environmental impacts of rural development projects. Strategies such as the suppression of vector populations through the provision of safe water supplies, proper sanitation, solid waste management facilities, sewerage and excreta disposal systems, water manipulation in dams and irrigation systems, vector diversion by zooprophylaxis, and vector exclusion by improved housing, are discussed with appropriate examples. Vectors of malaria, filariasis, Chagas' disease, and schistosomiasis have been controlled by drainage or filling aquatic breeding sites, improved housing and sanitation, the use of expanded polystyrene beads, zooprophylaxis, or the provision of household water supplies. Community participation has been effective in the suppression of dengue vectors in Mexico and the Dominican Republic. Alone or combined with other vector control methods, EM has been proven to be a successful approach to vector control in a number of places. The future of EM in vector control looks promising.

  10. [The Importance of Vector Management for Prevention of Hospital Infections].

    Science.gov (United States)

    Çetin, Hüseyin

    2015-09-01

    Many researches show that cockroaches, ants, some other arthropods and also rodents in hospitals, can act as potential vectors of medically important bacteria, fungi and parasites. The results of microbiological studies show that these animals play a significant role in the epidemiology of hospital infections. These vectors may be found inside of the kitchens, patient rooms, toilets, medicine stores, canteen and wards in health care environments. The importance of vector control in order to prevent the spread of nosocomial infections in healthcare facilities was discussed in this paper. This study also gives information on integrated control methods for vectors in hospitals.

  11. Integrated crisis management exercises

    International Nuclear Information System (INIS)

    Callen, R.B.; DeHart, R.E.

    1994-01-01

    This paper describes some of the steps that Mobil has taken to enhance their crisis management capability and to improve their readiness. The approach stretches from the individual plant level to Mobil's Corporate offices in Fairfax, Virginia. Some of the lessons learned from several integrated crisis management exercises are outlined and some areas where additional industry co-operation in crisis management could pay dividends are suggested

  12. DNA transformations of Candida tropicalis with replicating and integrative vectors.

    Science.gov (United States)

    Sanglard, D; Fiechter, A

    1992-12-01

    The alkane-assimilating yeast Candida tropicalis was used as a host for DNA transformations. A stable ade2 mutant (Ha900) obtained by UV-mutagenesis was used as a recipient for different vectors carrying selectable markers. A first vector, pMK16, that was developed for the transformation of C. albicans and carries an ADE2 gene marker and a Candida autonomously replicating sequence (CARS) element promoting autonomous replication, was compatible for transforming Ha900. Two transformant types were observed: (i) pink transformants which easily lose pMK16 under non-selective growth conditions; (ii) white transformants, in which the same plasmid exhibited a higher mitotic stability. In both cases pMK16 could be rescued from these cells in Escherichia coli. A second vector, pADE2, containing the isolated C. tropicalis ADE2, gene, was used to transform Ha900. This vector integrated in the yeast genome at homologous sites of the ade2 locus. Different integration types were observed at one or both ade2 alleles in single or in tandem repeats.

  13. Numerical computation of molecular integrals via optimized (vectorized) FORTRAN code

    International Nuclear Information System (INIS)

    Scott, T.C.; Grant, I.P.; Saunders, V.R.

    1997-01-01

    The calculation of molecular properties based on quantum mechanics is an area of fundamental research whose horizons have always been determined by the power of state-of-the-art computers. A computational bottleneck is the numerical calculation of the required molecular integrals to sufficient precision. Herein, we present a method for the rapid numerical evaluation of molecular integrals using optimized FORTRAN code generated by Maple. The method is based on the exploitation of common intermediates and the optimization can be adjusted to both serial and vectorized computations. (orig.)

  14. Management of arthropod pathogen vectors in North America: Minimizing adverse effects on pollinators

    Science.gov (United States)

    Ginsberg, Howard; Bargar, Timothy A.; Hladik, Michelle L.; Lubelczyk, Charles

    2017-01-01

    Tick and mosquito management is important to public health protection. At the same time, growing concerns about declines of pollinator species raise the question of whether vector control practices might affect pollinator populations. We report the results of a task force of the North American Pollinator Protection Campaign (NAPPC) that examined potential effects of vector management practices on pollinators, and how these programs could be adjusted to minimize negative effects on pollinating species. The main types of vector control practices that might affect pollinators are landscape manipulation, biocontrol, and pesticide applications. Some current practices already minimize effects of vector control on pollinators (e.g., short-lived pesticides and application-targeting technologies). Nontarget effects can be further diminished by taking pollinator protection into account in the planning stages of vector management programs. Effects of vector control on pollinator species often depend on specific local conditions (e.g., proximity of locations with abundant vectors to concentrations of floral resources), so planning is most effective when it includes collaborations of local vector management professionals with local experts on pollinators. Interventions can then be designed to avoid pollinators (e.g., targeting applications to avoid blooming times and pollinator nesting habitats), while still optimizing public health protection. Research on efficient targeting of interventions, and on effects on pollinators of emerging technologies, will help mitigate potential deleterious effects on pollinators in future management programs. In particular, models that can predict effects of integrated pest management on vector-borne pathogen transmission, along with effects on pollinator populations, would be useful for collaborative decision-making.

  15. Status of pesticide management in the practice of vector control: a global survey in countries at risk of malaria or other major vector-borne diseases

    Directory of Open Access Journals (Sweden)

    Tan Soo

    2011-05-01

    Full Text Available Abstract Background It is critical that vector control pesticides are used for their acceptable purpose without causing adverse effects on health and the environment. This paper provides a global overview of the current status of pesticides management in the practice of vector control. Methods A questionnaire was distributed to WHO member states and completed either by the director of the vector-borne disease control programme or by the national manager for vector control. In all, 113 countries responded to the questionnaire (80% response rate, representing 94% of the total population of the countries targeted. Results Major gaps were evident in countries in pesticide procurement practices, training on vector control decision making, certification and quality control of pesticide application, monitoring of worker safety, public awareness programmes, and safe disposal of pesticide-related waste. Nevertheless, basic conditions of policy and coordination have been established in many countries through which the management of vector control pesticides could potentially be improved. Most countries responded that they have adopted relevant recommendations by the WHO. Conclusions Given the deficiencies identified in this first global survey on public health pesticide management and the recent rise in pesticide use for malaria control, the effectiveness and safety of pesticide use are being compromised. This highlights the urgent need for countries to strengthen their capacity on pesticide management and evidence-based decision making within the context of an integrated vector management approach.

  16. Status of pesticide management in the practice of vector control: a global survey in countries at risk of malaria or other major vector-borne diseases.

    Science.gov (United States)

    van den Berg, Henk; Hii, Jeffrey; Soares, Agnes; Mnzava, Abraham; Ameneshewa, Birkinesh; Dash, Aditya P; Ejov, Mikhail; Tan, Soo Hian; Matthews, Graham; Yadav, Rajpal S; Zaim, Morteza

    2011-05-14

    It is critical that vector control pesticides are used for their acceptable purpose without causing adverse effects on health and the environment. This paper provides a global overview of the current status of pesticides management in the practice of vector control. A questionnaire was distributed to WHO member states and completed either by the director of the vector-borne disease control programme or by the national manager for vector control. In all, 113 countries responded to the questionnaire (80% response rate), representing 94% of the total population of the countries targeted. Major gaps were evident in countries in pesticide procurement practices, training on vector control decision making, certification and quality control of pesticide application, monitoring of worker safety, public awareness programmes, and safe disposal of pesticide-related waste. Nevertheless, basic conditions of policy and coordination have been established in many countries through which the management of vector control pesticides could potentially be improved. Most countries responded that they have adopted relevant recommendations by the WHO. Given the deficiencies identified in this first global survey on public health pesticide management and the recent rise in pesticide use for malaria control, the effectiveness and safety of pesticide use are being compromised. This highlights the urgent need for countries to strengthen their capacity on pesticide management and evidence-based decision making within the context of an integrated vector management approach.

  17. Integrated management systems

    DEFF Research Database (Denmark)

    Jørgensen, Tine Herreborg; Remmen, Arne; Mellado, M. Dolores

    2006-01-01

    Different approaches to integration of management systems (ISO 9001, ISO 14001, OHSAS 18001 and SA 8000) with various levels of ambition have emerged. The tendency of increased compatibility between these standards has paved the road for discussions of, how to understand the different aspects of ...

  18. Integrated Pest Management (IPM)

    Science.gov (United States)

    Repellents Rodenticides Other types of pesticides Disponible en español Integrated Pest Management (IPM) IPM Company: IPM is the Key - Oregon State University Extension Service Last updated May 11, 2018 Related Insecticides Natural and Biological Pesticides Repellents Rodenticides Other types of pesticides Disponible en

  19. Integrated groundwater data management

    Science.gov (United States)

    Fitch, Peter; Brodaric, Boyan; Stenson, Matt; Booth, Nathaniel; Jakeman, Anthony J.; Barreteau, Olivier; Hunt, Randall J.; Rinaudo, Jean-Daniel; Ross, Andrew

    2016-01-01

    The goal of a data manager is to ensure that data is safely stored, adequately described, discoverable and easily accessible. However, to keep pace with the evolution of groundwater studies in the last decade, the associated data and data management requirements have changed significantly. In particular, there is a growing recognition that management questions cannot be adequately answered by single discipline studies. This has led a push towards the paradigm of integrated modeling, where diverse parts of the hydrological cycle and its human connections are included. This chapter describes groundwater data management practices, and reviews the current state of the art with enterprise groundwater database management systems. It also includes discussion on commonly used data management models, detailing typical data management lifecycles. We discuss the growing use of web services and open standards such as GWML and WaterML2.0 to exchange groundwater information and knowledge, and the need for national data networks. We also discuss cross-jurisdictional interoperability issues, based on our experience sharing groundwater data across the US/Canadian border. Lastly, we present some future trends relating to groundwater data management.

  20. Automated innovative diagnostic, data management and communication tool, for improving malaria vector control in endemic settings.

    Science.gov (United States)

    Vontas, John; Mitsakakis, Konstantinos; Zengerle, Roland; Yewhalaw, Delenasaw; Sikaala, Chadwick Haadezu; Etang, Josiane; Fallani, Matteo; Carman, Bill; Müller, Pie; Chouaïbou, Mouhamadou; Coleman, Marlize; Coleman, Michael

    2016-01-01

    Malaria is a life-threatening disease that caused more than 400,000 deaths in sub-Saharan Africa in 2015. Mass prevention of the disease is best achieved by vector control which heavily relies on the use of insecticides. Monitoring mosquito vector populations is an integral component of control programs and a prerequisite for effective interventions. Several individual methods are used for this task; however, there are obstacles to their uptake, as well as challenges in organizing, interpreting and communicating vector population data. The Horizon 2020 project "DMC-MALVEC" consortium will develop a fully integrated and automated multiplex vector-diagnostic platform (LabDisk) for characterizing mosquito populations in terms of species composition, Plasmodium infections and biochemical insecticide resistance markers. The LabDisk will be interfaced with a Disease Data Management System (DDMS), a custom made data management software which will collate and manage data from routine entomological monitoring activities providing information in a timely fashion based on user needs and in a standardized way. The ResistanceSim, a serious game, a modern ICT platform that uses interactive ways of communicating guidelines and exemplifying good practices of optimal use of interventions in the health sector will also be a key element. The use of the tool will teach operational end users the value of quality data (relevant, timely and accurate) to make informed decisions. The integrated system (LabDisk, DDMS & ResistanceSim) will be evaluated in four malaria endemic countries, representative of the vector control challenges in sub-Saharan Africa, (Cameroon, Ivory Coast, Ethiopia and Zambia), highly representative of malaria settings with different levels of endemicity and vector control challenges, to support informed decision-making in vector control and disease management.

  1. Integrated parasite management

    DEFF Research Database (Denmark)

    Clausen, Jesper Hedegaard; Madsen, Henry; Van, Phan Thi

    2015-01-01

    communities at risk through mass drug administration. However, we argue that treatment alone will not reduce the risk from eating infected fish and that sustainable effective control must adopt an integrated FZT control approach based on education, infrastructure improvements, and management practices...... that target critical control points in the aquaculture production cycle identified from a thorough understanding of FZT and host biology and epidemiology. We present recommendations for an integrated parasite management (IPM) program for aquaculture farms.......Fishborne zoonotic trematodes (FZT) are an emerging problem and there is now a consensus that, in addition to wild-caught fish, fish produced in aquaculture present a major food safety risk, especially in Southeast Asia where aquaculture is important economically. Current control programs target...

  2. Viral Hybrid Vectors for Somatic Integration - Are They the Better Solution?

    Directory of Open Access Journals (Sweden)

    Anja Ehrhardt

    2009-12-01

    Full Text Available The turbulent history of clinical trials in viral gene therapy has taught us important lessons about vector design and safety issues. Much effort was spent on analyzing genotoxicity after somatic integration of therapeutic DNA into the host genome. Based on these findings major improvements in vector design including the development of viral hybrid vectors for somatic integration have been achieved. This review provides a state-of-the-art overview of available hybrid vectors utilizing viruses for high transduction efficiencies in concert with various integration machineries for random and targeted integration patterns. It discusses advantages but also limitations of each vector system.

  3. Integration vector for the cyanobacteria Synechocystis sp. 6803

    International Nuclear Information System (INIS)

    Shestakov, S.V.; Elanskaya, I.V.; Bibikova, M.V.

    1985-01-01

    The authors have constructed recombinant plasmid DNA molecules with fragments of chromosomal DNA of the cyanobacterium Synechocystis 6803 in the vector plasmid pACYC 184, carrying markers for resistance against tetracycline (TC/sup r/) and chloramphenicol (Cm/sup r/). The authors also present their scheme of constructing integration vectors for Synechocystis 6803. To demonstrate integration of the recombinant plasmids of pSIS and pSIB series into the chromosomes of cyanobacteria, chromosomal DNA was isolated from the Cm/sup r/ transformants of Synechocystis 6803, and used for blot-hybridization using P 32-labeled plasmid DNA of pACYC 184. The hybridization results show that the chromosomal DNA isolated from the Cm/sup r/ transformants of cyanobacteria carries a region homologous with plasmid pACYC 184, whereas the DNA from wild type cells does not hybridize with pACYC 184. The transformation frequency of the Synechocystis 6803 cells by chromosomal DNA from the Cm/sup r/ clones of cyanobacteria was 3-7 x 10 -5 , which corresponds to the frequency of chromosomal transformation for other markers

  4. Integrated management system

    International Nuclear Information System (INIS)

    Florescu, N.

    2003-01-01

    A management system is developed in order to reflect the needs of the business and to ensure that the objectives of the organization will be achieved. The process model and each individual process within the system then needs to identify the drives or requirements from external customers and stakeholders, regulations, and standards such as ISO and 50-C-Q. The processes are then developed to address these drivers. Developing the process in this way makes it fully integrated and capable of incorporating any new requirements. The International Standard (ISO 9000:2000) promotes the adoption of a process approach when developing, implementing and improving the effectiveness of a quality management system to enhance customer satisfaction by meeting customer requirements. The IAEA Code recognizes that the entire work is a process which can be planned, assessed and improved. For an organization to function effectively, numerous linked activities have to be identified and managed. By definition a process is an activity that using resources and taking into account all the constraints imposed executes the necessary operations which transform the inputs in outcomes. Running a system of processes within an organization, identification of the interaction between the processes and their management can be referred to as a 'process approach'. The advantage of such an approach is the ensuring of the ongoing control over the linkage between the individual processes composing the system as well as over their combination and interaction. Developing a management system implies: identification of the process which delivers Critical Success Factor (CSFs) of the business; identifying the support processes enabling the CSFs to be accomplished; identifying the processes that deliver the business fundamentals. An integrated management system should include all activities not only those related to Quality, Health and Safety. When developing an IMS it is necessary to identify all of the drivers

  5. Integral consideration of integrated management systems

    International Nuclear Information System (INIS)

    Frauenknecht, Stefan; Schmitz, Hans

    2010-01-01

    Aim of the project for the NPPs Kruemmel and Brunsbuettel (Vattenfall) is the integral view of the business process as basis for the implementation and operation of management systems in the domains quality, safety and environment. The authors describe the integral view of the business processes in the frame of integrated management systems with the focus nuclear safety, lessons learned in the past, the concept of a process-based controlling system and experiences from the practical realization.

  6. Integrated Financial Management Program

    Science.gov (United States)

    Pho, Susan

    2004-01-01

    Having worked in the Employees and Commercial Payments Branch of the Financial Management Division for the past 3 summers, I have seen the many changes that have occurred within the NASA organization. As I return each summer, I find that new programs and systems have been adapted to better serve the needs of the Center and of the Agency. The NASA Agency has transformed itself the past couple years with the implementation of the Integrated Financial Management Program (IFMP). IFMP is designed to allow the Agency to improve its management of its Financial, Physical, and Human Resources through the use of multiple enterprise module applications. With my mentor, Joseph Kan, being the branch chief of the Employees and Commercial Payments Branch, I have been exposed to several modules, such as Travel Manager, WebTads, and Core Financial/SAP, which were implemented in the last couple of years under the IFMP. The implementation of these agency-wide systems has sometimes proven to be troublesome. Prior to IFMP, each NASA Center utilizes their own systems for Payroll, Travel, Accounts Payable, etc. But with the implementation of the Integrated Financial Management Program, all the "legacy" systems had to be eliminated. As a result, a great deal of enhancement and preparation work is necessary to ease the transformation from the old systems to the new. All this work occurs simultaneously; for example, e-Payroll will "go live" in several months, but a system like Travel Manager will need to have information upgraded within the system to meet the requirements set by Headquarters. My assignments this summer have given me the opportunity to become involved with such work. So far, I have been given the opportunity to participate in projects resulting from a congressional request, several bankcard reconciliations, updating routing lists for Travel Manager, updating the majordomo list for Travel Manager approvers and point of contacts, and a NASA Headquarters project involving

  7. COMMUNICATION - CENTRAL VECTOR IN KNOWLEDGE MANAGEMENT

    Directory of Open Access Journals (Sweden)

    Adriana, GRIGORESCU

    2014-11-01

    Full Text Available As a key concept in modern management, the knowledge management among the knowledge administration, development and transfer between the members of an organization, it also involves the knowledge stimulation to obtain the competitive advantage and the innovations. The association between communication and knowledge is normal; the knowledge without communication is sterile, even useless. The communication's role in the knowledge management is both normal and valuable, because the knowledge, which is a good value, must be transferred so it can be exploited to maximum, and the knowledge transfer is possible only through communication. The managerial decisions, strategies, plans, explanations must be communicated to the organization's members so they know how, where and why it must be acted to assure its success. In turn, the organization's members hold a personal luggage of knowledge that can be developed and putted in the interests of the organization so it can become a collective source that generates new values. The present article presents the results of a research that had as purpose to identify in which way the communication is used to implement the knowledge management.

  8. Integrated refinery waste management

    Energy Technology Data Exchange (ETDEWEB)

    Shieh, Y -S [ETG Environmental, Inc., Blue Bell, PA (US); Sheehan, W J [Separation and Recovery Systems, Inc., Irvine, CA (US)

    1992-01-01

    In response to the RCRA land ban regulations and TC rule promulgated by the U.S. Federal Environmental Protection Agency (EPA) in 1988-1990, an Integrated Refinery Waste Management (IRWM) program has been developed to provide cost-effective solutions to petroleum industry customers. The goal of IRWM is to provide technology based remediation treatment services to manage sludges and wastewaters generated from the oil refining processes, soils contaminated with petroleum distillates and groundwater contaminated with fuels. Resource recovery, volume reduction and waste minimization are the primary choices to mitigate environmental problems. Oil recovery has been performed through phase separation (such as centrifugation and filtration) and heating of heavy oils. Volume reduction is achieved by dewatering systems such as centrifuges and filter presses, and low temperature thermal treatment. Waste minimization can be accomplished by bioremediation and resource recovery through a cement kiln. (Author).

  9. Vectors

    DEFF Research Database (Denmark)

    Boeriis, Morten; van Leeuwen, Theo

    2017-01-01

    should be taken into account in discussing ‘reactions’, which Kress and van Leeuwen link only to eyeline vectors. Finally, the question can be raised as to whether actions are always realized by vectors. Drawing on a re-reading of Rudolf Arnheim’s account of vectors, these issues are outlined......This article revisits the concept of vectors, which, in Kress and van Leeuwen’s Reading Images (2006), plays a crucial role in distinguishing between ‘narrative’, action-oriented processes and ‘conceptual’, state-oriented processes. The use of this concept in image analysis has usually focused...

  10. Integrated Disability Management

    Directory of Open Access Journals (Sweden)

    Silvia Angeloni

    2013-10-01

    Full Text Available This article sets out to increase awareness regarding the wide and universal significance of disability, as well as the important benefits of an Integrated Disability Management (IDM approach. The scientific basis for IDM is explored in the first place through an analysis of its relationship to the International Classification of Functioning, Disability and Health (ICF. The conceptual paradigm of the ICF shares an ideological position with the IDM approach in that they are both underpinned by dynamic and multidimensional constructions of disability, which imply equally holistic and interdisciplinary responses. The IDM approach can be applied across a diversity of human situations to provide solutions that reflect the multifaceted and widespread nature of disability. The IDM approach is intended as a strategy capable of handling: inclusion of people with disabilities, active aging of human resources, health and safety in the workplace, prevention of disabilities and various diseases, return-to-work, absenteeism, and presenteeism.

  11. Prolonged Integration Site Selection of a Lentiviral Vector in the Genome of Human Keratinocytes.

    Science.gov (United States)

    Qian, Wei; Wang, Yong; Li, Rui-Fu; Zhou, Xin; Liu, Jing; Peng, Dai-Zhi

    2017-03-03

    BACKGROUND Lentiviral vectors have been successfully used for human skin cell gene transfer studies. Defining the selection of integration sites for retroviral vectors in the host genome is crucial in risk assessment analysis of gene therapy. However, genome-wide analyses of lentiviral integration sites in human keratinocytes, especially after prolonged growth, are poorly understood. MATERIAL AND METHODS In this study, 874 unique lentiviral vector integration sites in human HaCaT keratinocytes after long-term culture were identified and analyzed with the online tool GTSG-QuickMap and SPSS software. RESULTS The data indicated that lentiviral vectors showed integration site preferences for genes and gene-rich regions. CONCLUSIONS This study will likely assist in determining the relative risks of the lentiviral vector system and in the design of a safe lentiviral vector system in the gene therapy of skin diseases.

  12. Integrated supply chain risk management

    OpenAIRE

    Riaan Bredell; Jackie Walters

    2007-01-01

    Integrated supply chain risk management (ISCRM) has become indispensable to the theory and practice of supply chain management. The economic and political realities of the modern world require not only a different approach to supply chain management, but also bold steps to secure supply chain performance and sustainable wealth creation. Integrated supply chain risk management provides supply chain organisations with a level of insight into their supply chains yet to be achieved. If correctly ...

  13. Integrated pest management

    International Nuclear Information System (INIS)

    LaBrecque, G.C.

    1981-01-01

    An effective Integrated Pest Management (IPM) programme requires a thorough knowledge of the biology of the target species, namely information on the dispersal, population densities and dynamics as well as the ecology of the natural enemies of the pest. Studies on these can be accomplished by radiolabelling techniques. In the event that conditions prevent the use of radioisotopes the insects can be labelled with either a rare earth or stable isotopes. All insects treated with the rare earths, once captured, are exposed to neutrons which produce radioactivity in the rare earths. There are two other approaches in the practical application of radiation to the problem of insect control: the exposure of insects to lethal doses of radiation and the release of sterile insects. The Insect and Pest Control Section contributes to all aspects of the sterile insect technique (SIT) and it is involved in the Agency's Coordinated Research Programme which permits scientists from the developing countries to meet to discuss agricultural problems and to devise means of solving crop-pest infestation problems by using isotopes and radiation. The success of radiation in insect pest control was underlined and reviewed at the international symposium on the sterile insect technique and the use of radiation in genetic insect control jointly organized by the FAO and the IAEA and held in the FRG in 1981. Another important action is the BICOT programme in Nigeria between the IAEA and the Government of Nigeria on the biological control of tsetse flies by SIT

  14. Integral control for population management.

    Science.gov (United States)

    Guiver, Chris; Logemann, Hartmut; Rebarber, Richard; Bill, Adam; Tenhumberg, Brigitte; Hodgson, Dave; Townley, Stuart

    2015-04-01

    We present a novel management methodology for restocking a declining population. The strategy uses integral control, a concept ubiquitous in control theory which has not been applied to population dynamics. Integral control is based on dynamic feedback-using measurements of the population to inform management strategies and is robust to model uncertainty, an important consideration for ecological models. We demonstrate from first principles why such an approach to population management is suitable via theory and examples.

  15. Integrated Information Management (IIM)

    National Research Council Canada - National Science Library

    McIlvain, Jason

    2007-01-01

    Information Technology is the core capability required to align our resources and increase our effectiveness on the battlefield by integrating and coordinating our preventative measures and responses...

  16. Integrated supply chain risk management

    Directory of Open Access Journals (Sweden)

    Riaan Bredell

    2007-11-01

    Full Text Available Integrated supply chain risk management (ISCRM has become indispensable to the theory and practice of supply chain management. The economic and political realities of the modern world require not only a different approach to supply chain management, but also bold steps to secure supply chain performance and sustainable wealth creation. Integrated supply chain risk management provides supply chain organisations with a level of insight into their supply chains yet to be achieved. If correctly applied, this process may optimise management decision-making and assist in the protection and enhancement of shareholder value.

  17. Integrated data management for RODOS

    International Nuclear Information System (INIS)

    Abramowicz, K.; Koschel, A.; Rafat, M.; Wendelgass, R.

    1995-12-01

    The report presents the results of a feasibility study on an integrated data organisation and management in RODOS, the real-time on-line decision support system for off-site nuclear emergency management. The conceptual design of the functional components of the integrated data management are described taking account of the software components and the operation environment of the RODOS system. In particular, the scheme architecture of a database integration manager for accessing and updating a multi-database system is discussed in detail under a variety of database management aspects. Furthermore, the structural design of both a simple knowledge database and a real-time database are described. Finally, some short comments on the benefits and disadvantages of the proposed concept of data integration in RODOS are given. (orig.) [de

  18. Integrated Building Health Management

    Data.gov (United States)

    National Aeronautics and Space Administration — Abstract: Building health management is an important part in running an efficient and cost-effective building. Many problems in a building’s system can go undetected...

  19. Towards the Development of an Automated Learning Assistant for Vector Calculus: Integration over Planar Regions

    Science.gov (United States)

    Yaacob, Yuzita; Wester, Michael; Steinberg, Stanly

    2010-01-01

    This paper presents a prototype of a computer learning assistant ILMEV (Interactive Learning-Mathematica Enhanced Vector calculus) package with the purpose of helping students to understand the theory and applications of integration in vector calculus. The main problem for students using Mathematica is to convert a textbook description of a…

  20. Underpinning sustainable vector control through informed insecticide resistance management.

    Directory of Open Access Journals (Sweden)

    Edward K Thomsen

    Full Text Available There has been rapid scale-up of malaria vector control in the last ten years. Both of the primary control strategies, long-lasting pyrethroid treated nets and indoor residual spraying, rely on the use of a limited number of insecticides. Insecticide resistance, as measured by bioassay, has rapidly increased in prevalence and has come to the forefront as an issue that needs to be addressed to maintain the sustainability of malaria control and the drive to elimination. Zambia's programme reported high levels of resistance to the insecticides it used in 2010, and, as a result, increased its investment in resistance monitoring to support informed resistance management decisions.A country-wide survey on insecticide resistance in Zambian malaria vectors was performed using WHO bioassays to detect resistant phenotypes. Molecular techniques were used to detect target-site mutations and microarray to detect metabolic resistance mechanisms. Anopheles gambiae s.s. was resistant to pyrethroids, DDT and carbamates, with potential organophosphate resistance in one population. The resistant phenotypes were conferred by both target-site and metabolic mechanisms. Anopheles funestus s.s. was largely resistant to pyrethroids and carbamates, with potential resistance to DDT in two locations. The resistant phenotypes were conferred by elevated levels of cytochrome p450s.Currently, the Zambia National Malaria Control Centre is using these results to inform their vector control strategy. The methods employed here can serve as a template to all malaria-endemic countries striving to create a sustainable insecticide resistance management plan.

  1. Adaptive and integrated water management

    NARCIS (Netherlands)

    Pahl-Wostl, C.; Kabat, P.; Möltgen, J.

    2007-01-01

    Sustainable water management is a key environmental challenge of the 21st century. Developing and implementing innovative management approaches and how to cope with the increasing complexity and uncertainties was the theme of the first International Conference on Adaptive and Integrated Water

  2. Integrated coastal management in Uruguay

    International Nuclear Information System (INIS)

    2011-01-01

    Integrated coastal management in Uruguay Carmelo includes the following areas-Nueva Palmira challenges and opportunities for local development in a context of large-scale industrial (Conchillas Uruguay), coastal management and stream Arroyo Solis Solis Chico Grande, Punta Colorada and Punta Negra, Maldonado Province Arroyo Valizas and sustainable tourism.

  3. Networking of integrated pest management

    NARCIS (Netherlands)

    Lamichhane, Jay Ram; Aubertot, Jean Noël; Begg, Graham; Birch, Andrew Nicholas E.; Boonekamp, Piet; Dachbrodt-Saaydeh, Silke; Hansen, Jens Grønbech; Hovmøller, Mogens Støvring; Jensen, Jens Erik; Jørgensen, Lise Nistrup; Kiss, Jozsef; Kudsk, Per; Moonen, Anna Camilla; Rasplus, Jean Yves; Sattin, Maurizio; Streito, Jean Claude; Messéan, Antoine

    2016-01-01

    Integrated pest management (IPM) is facing both external and internal challenges. External challenges include increasing needs to manage pests (pathogens, animal pests and weeds) due to climate change, evolution of pesticide resistance as well as virulence matching host resistance. The complexity

  4. Integration profile and safety of an adenovirus hybrid-vector utilizing hyperactive sleeping beauty transposase for somatic integration.

    Directory of Open Access Journals (Sweden)

    Wenli Zhang

    Full Text Available We recently developed adenovirus/transposase hybrid-vectors utilizing the previously described hyperactive Sleeping Beauty (SB transposase HSB5 for somatic integration and we could show stabilized transgene expression in mice and a canine model for hemophilia B. However, the safety profile of these hybrid-vectors with respect to vector dose and genotoxicity remains to be investigated. Herein, we evaluated this hybrid-vector system in C57Bl/6 mice with escalating vector dose settings. We found that in all mice which received the hyperactive SB transposase, transgene expression levels were stabilized in a dose-dependent manner and that the highest vector dose was accompanied by fatalities in mice. To analyze potential genotoxic side-effects due to somatic integration into host chromosomes, we performed a genome-wide integration site analysis using linker-mediated PCR (LM-PCR and linear amplification-mediated PCR (LAM-PCR. Analysis of genomic DNA samples obtained from HSB5 treated female and male mice revealed a total of 1327 unique transposition events. Overall the chromosomal distribution pattern was close-to-random and we observed a random integration profile with respect to integration into gene and non-gene areas. Notably, when using the LM-PCR protocol, 27 extra-chromosomal integration events were identified, most likely caused by transposon excision and subsequent transposition into the delivered adenoviral vector genome. In total, this study provides a careful evaluation of the safety profile of adenovirus/Sleeping Beauty transposase hybrid-vectors. The obtained information will be useful when designing future preclinical studies utilizing hybrid-vectors in small and large animal models.

  5. Numerical solution of integral equations, describing mass spectrum of vector mesons

    International Nuclear Information System (INIS)

    Zhidkov, E.P.; Nikonov, E.G.; Sidorov, A.V.; Skachkov, N.B.; Khoromskij, B.N.

    1988-01-01

    The description of the numerical algorithm for solving quasipotential integral equation in impulse space is presented. The results of numerical computations of the vector meson mass spectrum and the leptonic decay width are given in comparison with the experimental data

  6. Integration of vectors by homologous recombination in the plant pathogen Glomerella cingulata.

    Science.gov (United States)

    Rikkerink, E H; Solon, S L; Crowhurst, R N; Templeton, M D

    1994-03-01

    An homologous transformation system has been developed for the plant pathogenic fungus Glomerella cingulata (Colletotrichum gloeosporioides). A transformation vector containing the G. cingulata gpdA promoter fused to the hygromycin phosphotransferase gene was constructed. Southern analyses indicated that this vector integrated at single sites in most transformants. A novel method of PCR amplification across the recombination junction point indicated that the integration event occurred by homologous recombination in more than 95% of the transformants. Deletion studies demonstrated that 505 bp (the minimum length of homologous promoter DNA analysed which was still capable of promoter function) was sufficient to target integration events. Homologous integration of the vector resulted in duplication of the gdpA promoter region. When transformants were grown without selective pressure, a high incidence of vector excision by recombination between the duplicated regions was evident. The significance of these recombination characteristics is discussed with reference to the feasibility of performing gene disruption experiments.

  7. INTEGRATION OF ENVIRONMENTAL MANAGEMENT SYSTEM

    OpenAIRE

    Tomescu Ada Mirela

    2012-01-01

    The relevance of management as significant factor of business activity can be established on various management systems. These will help to obtain, organise, administrate, evaluate and control particulars: information, quality, environmental protection, health and safety, various resources (time, human, finance, inventory etc). The complexity of nowadays days development, forced us to think ‘integrated’. Sustainable development principles require that environment management policies and p...

  8. Intelligent Integrated System Health Management

    Science.gov (United States)

    Figueroa, Fernando

    2012-01-01

    Intelligent Integrated System Health Management (ISHM) is the management of data, information, and knowledge (DIaK) with the purposeful objective of determining the health of a system (Management: storage, distribution, sharing, maintenance, processing, reasoning, and presentation). Presentation discusses: (1) ISHM Capability Development. (1a) ISHM Knowledge Model. (1b) Standards for ISHM Implementation. (1c) ISHM Domain Models (ISHM-DM's). (1d) Intelligent Sensors and Components. (2) ISHM in Systems Design, Engineering, and Integration. (3) Intelligent Control for ISHM-Enabled Systems

  9. A Riesz Representation Theorem for the Space of Henstock Integrable Vector-Valued Functions

    Directory of Open Access Journals (Sweden)

    Tomás Pérez Becerra

    2018-01-01

    Full Text Available Using a bounded bilinear operator, we define the Henstock-Stieltjes integral for vector-valued functions; we prove some integration by parts theorems for Henstock integral and a Riesz-type theorem which provides an alternative proof of the representation theorem for real functions proved by Alexiewicz.

  10. A General Representation Theorem for Integrated Vector Autoregressive Processes

    DEFF Research Database (Denmark)

    Franchi, Massimo

    We study the algebraic structure of an I(d) vector autoregressive process, where d is restricted to be an integer. This is useful to characterize its polynomial cointegrating relations and its moving average representation, that is to prove a version of the Granger representation theorem valid...

  11. Cost-effectiveness of environmental management for vector control in resource development projects.

    Science.gov (United States)

    Bos, R

    1991-01-01

    Vector control methods are traditionally divided in chemical, biological and environmental management approaches, and this distinction also reflected in certain financial and economic aspects. This is particularly true for environmental modification, usually engineering or other structural works. It is highly capital intensive, as opposed to chemical and biological control which require recurrent expenditures, and discount rates are therefore a prominent consideration in deciding for one or the other approach. Environmental manipulation requires recurrent action, but can often be carried out with the community participation, which raises the issue of opportunity costs. The incorporation of environmental management in resource projects is generally impeded by economic considerations. The Internal Rate of Return continues to be a crucial criterion for funding agencies and development banks to support new projects; at the same time Governments of debt-riden countries in the Third World will do their best to avoid additional loans on such frills as environmental and health safeguards. Two approaches can be recommended to nevertheless ensure the incorporation of environmental management measures in resource projects in an affordable way. First, there are several examples of cases where environmental management measures either have a dual benefit (increasing both agricultural production and reducing vector-borne disease transmission) or can be implemented at zero costs. Second, the additional costs involved in structural modifications can be separated from the project development costs considered in the calculations of the Internal Rate of Return, and financial support can be sought from bilateral technical cooperation agencies particularly interested in environmental and health issues. There is a dearth of information in the cost-effectiveness of alternative vector control strategies in the developing country context. The process of integrating vector control in the

  12. Integrating principal component analysis and vector quantization with support vector regression for sulfur content prediction in HDS process

    Directory of Open Access Journals (Sweden)

    Shokri Saeid

    2015-01-01

    Full Text Available An accurate prediction of sulfur content is very important for the proper operation and product quality control in hydrodesulfurization (HDS process. For this purpose, a reliable data- driven soft sensors utilizing Support Vector Regression (SVR was developed and the effects of integrating Vector Quantization (VQ with Principle Component Analysis (PCA were studied on the assessment of this soft sensor. First, in pre-processing step the PCA and VQ techniques were used to reduce dimensions of the original input datasets. Then, the compressed datasets were used as input variables for the SVR model. Experimental data from the HDS setup were employed to validate the proposed integrated model. The integration of VQ/PCA techniques with SVR model was able to increase the prediction accuracy of SVR. The obtained results show that integrated technique (VQ-SVR was better than (PCA-SVR in prediction accuracy. Also, VQ decreased the sum of the training and test time of SVR model in comparison with PCA. For further evaluation, the performance of VQ-SVR model was also compared to that of SVR. The obtained results indicated that VQ-SVR model delivered the best satisfactory predicting performance (AARE= 0.0668 and R2= 0.995 in comparison with investigated models.

  13. Integrated Project Management System description

    International Nuclear Information System (INIS)

    1987-03-01

    The Uranium Mill Tailings Remedial Action (UMTRA) Project is a Department of Energy (DOE) designated Major System Acquisition (MSA). To execute and manage the Project mission successfully and to comply with the MSA requirements, the UMTRA Project Office (''Project Office'') has implemented and operates an Integrated Project Management System (IPMS). The Project Office is assisted by the Technical Assistance Contractor's (TAC) Project Integration and Control (PIC) Group in system operation. Each participant, in turn, provides critical input to system operation and reporting requirements. The IPMS provides a uniform structured approach for integrating the work of Project participants. It serves as a tool for planning and control, workload management, performance measurement, and specialized reporting within a standardized format. This system description presents the guidance for its operation. Appendices 1 and 2 contain definitions of commonly used terms and abbreviations and acronyms, respectively. 17 figs., 5 tabs

  14. An Integrated Knowledge Management System

    Directory of Open Access Journals (Sweden)

    Vasile Mazilescu

    2014-11-01

    Full Text Available The aim of this paper is to present a Knowledge Management System based on Fuzzy Logic (FLKMS, a real-time expert system to meet the challenges of the dynamic environment. The main feature of our integrated shell FLKMS is that it models and integrates the temporal relationships between the dynamic of the evolution of an economic process with some fuzzy inferential methods, using a knowledge model for control, embedded within the expert system’s operational knowledge base.

  15. Integrated Urban Water Quality Management

    DEFF Research Database (Denmark)

    Rauch, W.; Harremoës, Poul

    1995-01-01

    The basic features of integrated urban water quality management by means of deterministic modeling are outlined. Procedures for the assessment of the detrimental effects in the recipient are presented as well as the basic concepts of an integrated model. The analysis of a synthetic urban drainage...... system provides useful information for water quality management. It is possible to identify the system parameters that contain engineering significance. Continuous simulation of the system performance indicates that the combined nitrogen loading is dominated by the wastewater treatment plant during dry...

  16. Integrated project management type contracts

    International Nuclear Information System (INIS)

    Heisler, S.I.

    1975-01-01

    The concept of integrated project management represents a single source to which the owner can turn for all project management functions excepting for those relating to outside parties such as site purchase, personnel selection etc. Other functions such as design, procurement, construction management, schedule and cost control, quality assurance/quality control are usually handled by the integrated project manager as the agent of the owner. The arrangement is flexible and the responsibilities can be varied to suit the size and experience of the owner. Past experience in the United States indicates an increase in the trend toward IPM work and it appears that overseas this trend is developing also. (orig./RW) [de

  17. Hybrid Lentivirus-transposon Vectors With a Random Integration Profile in Human Cells

    DEFF Research Database (Denmark)

    Staunstrup, Nicklas H; Moldt, Brian; Mátés, Lajos

    2009-01-01

    Gene delivery by human immunodeficiency virus type 1 (HIV-1)-based lentiviral vectors (LVs) is efficient, but genomic integration of the viral DNA is strongly biased toward transcriptionally active loci resulting in an increased risk of insertional mutagenesis in gene therapy protocols. Nonviral...... Sleeping Beauty (SB) transposon vectors have a significantly safer insertion profile, but efficient delivery into relevant cell/tissue types is a limitation. In an attempt to combine the favorable features of the two vector systems we established a novel hybrid vector technology based on SB transposase......-mediated insertion of lentiviral DNA circles generated during transduction of target cells with integrase (IN)-defective LVs (IDLVs). By construction of a lentivirus-transposon hybrid vector allowing transposition exclusively from circular viral DNA substrates, we demonstrate that SB transposase added in trans...

  18. Integrated Foreign Exchange Risk Management

    DEFF Research Database (Denmark)

    Aabo, Tom; Høg, Esben; Kuhn, Jochen

    Empirical research has focused on export as a proxy for the exchange rate exposure and the use of foreign exchange derivatives as the instrument to deal with this exposure. This empirical study applies an integrated foreign exchange risk management approach with a particular focus on the role...

  19. Implementation of integrated management system

    International Nuclear Information System (INIS)

    Gaspar Junior, Joao Carlos A.; Fonseca, Victor Zidan da

    2007-01-01

    In present day exist quality assurance system, environment, occupational health and safety such as ISO9001, ISO14001 and OHSAS18001 and others standards will can create. These standards can be implemented and certified they guarantee one record system, quality assurance, documents control, operational control, responsibility definition, training, preparing and serve to emergency, monitoring, internal audit, corrective action, continual improvement, prevent of pollution, write procedure, reduce costs, impact assessment, risk assessment , standard, decree, legal requirements of municipal, state, federal and local scope. These procedure and systems when isolate applied cause many management systems and bureaucracy. Integration Management System reduce to bureaucracy, excess of documents, documents storage and conflict documents and easy to others standards implementation in future. The Integrated Management System (IMS) will be implemented in 2007. INB created a management group for implementation, this group decides planing, works, policy and advertisement. Legal requirements were surveyed, internal audits, pre-audits and audits were realized. INB is partially in accordance with ISO14001, OSHAS18001 standards. But very soon, it will be totally in accordance with this norms. Many studies and works were contracted to deal with legal requirements. This work have intention of show implementation process of ISO14001, OHSAS18001 and Integrated Management System on INB. (author)

  20. Integration of adeno-associated virus vectors in CD34+ human hematopoietic progenitor cells after transduction.

    Science.gov (United States)

    Fisher-Adams, G; Wong, K K; Podsakoff, G; Forman, S J; Chatterjee, S

    1996-07-15

    Gene transfer vectors based on adeno-associated virus (AAV) appear promising because of their high transduction frequencies regardless of cell cycle status and ability to integrate into chromosomal DNA. We tested AAV-mediated gene transfer into a panel of human bone marrow or umbilical cord-derived CD34+ hematopoietic progenitor cells, using vectors encoding several transgenes under the control of viral and cellular promoters. Gene transfer was evaluated by (1) chromosomal integration of vector sequences and (2) analysis of transgene expression. Southern hybridization and fluorescence in situ hybridization analysis of transduced CD34 genomic DNA showed the presence of integrated vector sequences in chromosomal DNA in a portion of transduced cells and showed that integrated vector sequences were replicated along with cellular DNA during mitosis. Transgene expression in transduced CD34 cells in suspension cultures and in myeloid colonies differentiating in vitro from transduced CD34 cells approximated that predicted by the multiplicity of transduction. This was true in CD34 cells from different donors, regardless of the transgene or selective pressure. Comparisons of CD34 cell transduction either before or after cytokine stimulation showed similar gene transfer frequencies. Our findings suggest that AAV transduction of CD34+ hematopoietic progenitor cells is efficient, can lead to stable integration in a population of transduced cells, and may therefore provide the basis for safe and efficient ex vivo gene therapy of the hematopoietic system.

  1. Optical propagators in vector and spinor theories by path integral formalism

    International Nuclear Information System (INIS)

    Linares, J.

    1993-01-01

    The construction of an extended parabolic (wide-angle) vector and spinor wave theory is presented. For that, optical propagators in monochromatic vector light optics and monoenergetic spinor electron optics are evaluated by the path integral formalism. The auxiliary parameter method introduced by Fock and the Feynman-Dyson perturbative series are used. The proposed theory supplies, by a generalized Fermat's principle, the Mukunda-Simon-Sudarshan transformation for the passage from scalar to vector light (or spinor electron) optics in an asymptotic approximation. (author). 19 refs

  2. Spatially explicit multi-criteria decision analysis for managing vector-borne diseases

    Science.gov (United States)

    2011-01-01

    The complex epidemiology of vector-borne diseases creates significant challenges in the design and delivery of prevention and control strategies, especially in light of rapid social and environmental changes. Spatial models for predicting disease risk based on environmental factors such as climate and landscape have been developed for a number of important vector-borne diseases. The resulting risk maps have proven value for highlighting areas for targeting public health programs. However, these methods generally only offer technical information on the spatial distribution of disease risk itself, which may be incomplete for making decisions in a complex situation. In prioritizing surveillance and intervention strategies, decision-makers often also need to consider spatially explicit information on other important dimensions, such as the regional specificity of public acceptance, population vulnerability, resource availability, intervention effectiveness, and land use. There is a need for a unified strategy for supporting public health decision making that integrates available data for assessing spatially explicit disease risk, with other criteria, to implement effective prevention and control strategies. Multi-criteria decision analysis (MCDA) is a decision support tool that allows for the consideration of diverse quantitative and qualitative criteria using both data-driven and qualitative indicators for evaluating alternative strategies with transparency and stakeholder participation. Here we propose a MCDA-based approach to the development of geospatial models and spatially explicit decision support tools for the management of vector-borne diseases. We describe the conceptual framework that MCDA offers as well as technical considerations, approaches to implementation and expected outcomes. We conclude that MCDA is a powerful tool that offers tremendous potential for use in public health decision-making in general and vector-borne disease management in particular

  3. Spatially explicit multi-criteria decision analysis for managing vector-borne diseases

    Directory of Open Access Journals (Sweden)

    Hongoh Valerie

    2011-12-01

    Full Text Available Abstract The complex epidemiology of vector-borne diseases creates significant challenges in the design and delivery of prevention and control strategies, especially in light of rapid social and environmental changes. Spatial models for predicting disease risk based on environmental factors such as climate and landscape have been developed for a number of important vector-borne diseases. The resulting risk maps have proven value for highlighting areas for targeting public health programs. However, these methods generally only offer technical information on the spatial distribution of disease risk itself, which may be incomplete for making decisions in a complex situation. In prioritizing surveillance and intervention strategies, decision-makers often also need to consider spatially explicit information on other important dimensions, such as the regional specificity of public acceptance, population vulnerability, resource availability, intervention effectiveness, and land use. There is a need for a unified strategy for supporting public health decision making that integrates available data for assessing spatially explicit disease risk, with other criteria, to implement effective prevention and control strategies. Multi-criteria decision analysis (MCDA is a decision support tool that allows for the consideration of diverse quantitative and qualitative criteria using both data-driven and qualitative indicators for evaluating alternative strategies with transparency and stakeholder participation. Here we propose a MCDA-based approach to the development of geospatial models and spatially explicit decision support tools for the management of vector-borne diseases. We describe the conceptual framework that MCDA offers as well as technical considerations, approaches to implementation and expected outcomes. We conclude that MCDA is a powerful tool that offers tremendous potential for use in public health decision-making in general and vector

  4. Integrated therapy safety management system.

    Science.gov (United States)

    Podtschaske, Beatrice; Fuchs, Daniela; Friesdorf, Wolfgang

    2013-09-01

    The aim is to demonstrate the benefit of the medico-ergonomic approach for the redesign of clinical work systems. Based on the six layer model, a concept for an 'integrated therapy safety management' is drafted. This concept could serve as a basis to improve resilience. The concept is developed through a concept-based approach. The state of the art of safety and complexity research in human factors and ergonomics forms the basis. The findings are synthesized to a concept for 'integrated therapy safety management'. The concept is applied by way of example for the 'medication process' to demonstrate its practical implementation. The 'integrated therapy safety management' is drafted in accordance with the six layer model. This model supports a detailed description of specific work tasks, the corresponding responsibilities and related workflows at different layers by using the concept of 'bridge managers'. 'Bridge managers' anticipate potential errors and monitor the controlled system continuously. If disruptions or disturbances occur, they respond with corrective actions which ensure that no harm results and they initiate preventive measures for future procedures. The concept demonstrates that in a complex work system, the human factor is the key element and final authority to cope with the residual complexity. The expertise of the 'bridge managers' and the recursive hierarchical structure results in highly adaptive clinical work systems and increases their resilience. The medico-ergonomic approach is a highly promising way of coping with two complexities. It offers a systematic framework for comprehensive analyses of clinical work systems and promotes interdisciplinary collaboration. © 2013 The Authors. British Journal of Clinical Pharmacology © 2013 The British Pharmacological Society.

  5. ASPECTS OF INTEGRATION MANAGEMENT METHODS

    Directory of Open Access Journals (Sweden)

    Artemy Varshapetian

    2015-10-01

    Full Text Available For manufacturing companies to succeed in today's unstable economic environment, it is necessary to restructure the main components of its activities: designing innovative product, production using modern reconfigurable manufacturing systems, a business model that takes into account the global strategy and management methods using modern management models and tools. The first three components are discussed in numerous publications, for example, (Koren, 2010 and is therefore not considered in the article. A large number of publications devoted to the methods and tools of production management, for example (Halevi, 2007. On the basis of what was said in the article discusses the possibility of the integration of only three methods have received in recent years, the most widely used, namely: Six Sigma method - SS (George et al., 2005 and supplements its-Design for six sigm? - DFSS (Taguchi, 2003; Lean production transformed with the development to the "Lean management" and further to the "Lean thinking" - Lean (Hirano et al., 2006; Theory of Constraints, developed E.Goldratt - TOC (Dettmer, 2001. The article investigates some aspects of this integration: applications in diverse fields, positive features, changes in management structure, etc.

  6. Design Integration of Facilities Management

    DEFF Research Database (Denmark)

    Jensen, Per Anker

    2009-01-01

    One of the problems in the building industry is a limited degree of learning from experiences of use and operation of existing buildings. Development of professional facilities management (FM) can be seen as the missing link to bridge the gap between building operation and building design....... Strategies, methods and barriers for the transfer and integration of operational knowledge into the design process are discussed. Multiple strategies are needed to improve the integration of FM in design. Building clients must take on a leading role in defining and setting up requirements and procedures...... on literature studies and case studies from the Nordic countries in Europe, including research reflections on experiences from a main case study, where the author, before becoming a university researcher, was engaged in the client organization as deputy project director with responsibility for the integration...

  7. DKIST facility management system integration

    Science.gov (United States)

    White, Charles R.; Phelps, LeEllen

    2016-07-01

    The Daniel K. Inouye Solar Telescope (DKIST) Observatory is under construction at Haleakalā, Maui, Hawai'i. When complete, the DKIST will be the largest solar telescope in the world. The Facility Management System (FMS) is a subsystem of the high-level Facility Control System (FCS) and directly controls the Facility Thermal System (FTS). The FMS receives operational mode information from the FCS while making process data available to the FCS and includes hardware and software to integrate and control all aspects of the FTS including the Carousel Cooling System, the Telescope Chamber Environmental Control Systems, and the Temperature Monitoring System. In addition it will integrate the Power Energy Management System and several service systems such as heating, ventilation, and air conditioning (HVAC), the Domestic Water Distribution System, and the Vacuum System. All of these subsystems must operate in coordination to provide the best possible observing conditions and overall building management. Further, the FMS must actively react to varying weather conditions and observational requirements. The physical impact of the facility must not interfere with neighboring installations while operating in a very environmentally and culturally sensitive area. The FMS system will be comprised of five Programmable Automation Controllers (PACs). We present a pre-build overview of the functional plan to integrate all of the FMS subsystems.

  8. Nuclear Plant Integrated Outage Management

    International Nuclear Information System (INIS)

    Gerstberger, C. R.; Coulehan, R. J.; Tench, W. A.

    1992-01-01

    This paper is a discussion of an emerging concept for improving nuclear plant outage performance - integrated outage management. The paper begins with an explanation of what the concept encompasses, including a scope definition of the service and descriptions of the organization structure, various team functions, and vendor/customer relationships. The evolvement of traditional base scope services to the integrated outage concept is addressed and includes discussions on changing customer needs, shared risks, and a partnership approach to outages. Experiences with concept implementation from a single service in 1984 to the current volume of integrated outage management presented in this paper. We at Westinghouse believe that the operators of nuclear power plants will continue to be aggressively challenged in the next decade to improve the operating and financial performance of their units. More and more customers in the U. S. are looking towards integrated outage as the way to meet these challenges of the 1990s, an arrangement that is best implemented through a long-term partnering with a single-source supplier of high quality nuclear and turbine generator outage services. This availability, and other important parameters

  9. Integrating ribosomal promoter vectors that offer a choice of constitutive expression profiles in Leishmania donovani.

    Science.gov (United States)

    Soysa, Radika; Tran, Khoa D; Ullman, Buddy; Yates, Phillip A

    2015-12-01

    We have designed a novel series of integrating ribosomal RNA promoter vectors with five incrementally different constitutive expression profiles, covering a 250-fold range. Differential expression was achieved by placing different combinations of synthetic or leishmanial DNA sequences upstream and downstream of the transgene coding sequence in order to modulate pre-mRNA processing efficiency and mRNA stability, respectively. All of the vectors have extensive multiple cloning sites, and versions are available for producing N- or C- terminal GFP fusions at each of the possible relative expression levels. In addition, the modular configuration of the vectors allows drug resistance cassettes and other components to be readily exchanged. In toto, these vectors should be useful additions to the toolkit available for molecular and genetic studies of Leishmania donovani. Copyright © 2016 Elsevier B.V. All rights reserved.

  10. Towards an integrated approach in surveillance of vector-borne diseases in Europe

    Science.gov (United States)

    2011-01-01

    Vector borne disease (VBD) emergence is a complex and dynamic process. Interactions between multiple disciplines and responsible health and environmental authorities are often needed for an effective early warning, surveillance and control of vectors and the diseases they transmit. To fully appreciate this complexity, integrated knowledge about the human and the vector population is desirable. In the current paper, important parameters and terms of both public health and medical entomology are defined in order to establish a common language that facilitates collaboration between the two disciplines. Special focus is put on the different VBD contexts with respect to the current presence or absence of the disease, the pathogen and the vector in a given location. Depending on the context, whether a VBD is endemic or not, surveillance activities are required to assess disease burden or threat, respectively. Following a decision for action, surveillance activities continue to assess trends. PMID:21967706

  11. INTEGRATION OF ENVIRONMENTAL MANAGEMENT SYSTEM

    Directory of Open Access Journals (Sweden)

    Tomescu Ada Mirela

    2012-07-01

    Full Text Available The relevance of management as significant factor of business activity can be established on various management systems. These will help to obtain, organise, administrate, evaluate and control particulars: information, quality, environmental protection, health and safety, various resources (time, human, finance, inventory etc. The complexity of nowadays days development, forced us to think ‘integrated’. Sustainable development principles require that environment management policies and practices are not good in themselves but also integrate with all other environmental objectives, and with social and economic development objectives. The principles of sustainable development involve that environment management policies and practices. These are not sound in them-self but also integrate with all other environmental objectives, and with social and economic development objectives. Those objectives were realized, and followed by development of strategies to effects the objective of sustainable development. Environmental management should embrace recent change in the area of environmental protection, and suit the recently regulations of the field -entire legal and economic, as well as perform management systems to meet the requirements of the contemporary model for economic development. These changes are trailed by abandon the conventional approach of environmental protection and it is replaced by sustainable development (SD. The keys and the aims of Cleaner Productions (CP are presented being implemented in various companies as a non-formalised environmental management system (EMS. This concept is suggested here as a proper model for practice where possible environmental harmful technologies are used -e.g. Rosia Montana. Showing the features and the power of CP this paper is a signal oriented to involve the awareness of policy-makers and top management of diverse Romanian companies. Many companies in European countries are developing

  12. The Integrated Mode Management Interface

    Science.gov (United States)

    Hutchins, Edwin

    1996-01-01

    Mode management is the processes of understanding the character and consequences of autoflight modes, planning and selecting the engagement, disengagement and transitions between modes, and anticipating automatic mode transitions made by the autoflight system itself. The state of the art is represented by the latest designs produced by each of the major airframe manufacturers, the Boeing 747-400, the Boeing 777, the McDonnell Douglas MD-11, and the Airbus A320/A340 family of airplanes. In these airplanes autoflight modes are selected by manipulating switches on the control panel. The state of the autoflight system is displayed on the flight mode annunciators. The integrated mode management interface (IMMI) is a graphical interface to autoflight mode management systems for aircraft equipped with flight management computer systems (FMCS). The interface consists of a vertical mode manager and a lateral mode manager. Autoflight modes are depicted by icons on a graphical display. Mode selection is accomplished by touching (or mousing) the appropriate icon. The IMMI provides flight crews with an integrated interface to autoflight systems for aircraft equipped with flight management computer systems (FMCS). The current version is modeled on the Boeing glass-cockpit airplanes (747-400, 757/767). It runs on the SGI Indigo workstation. A working prototype of this graphics-based crew interface to the autoflight mode management tasks of glass cockpit airplanes has been installed in the Advanced Concepts Flight Simulator of the CSSRF of NASA Ames Research Center. This IMMI replaces the devices in FMCS equipped airplanes currently known as mode control panel (Boeing), flight guidance control panel (McDonnell Douglas), and flight control unit (Airbus). It also augments the functions of the flight mode annunciators. All glass cockpit airplanes are sufficiently similar that the IMMI could be tailored to the mode management system of any modern cockpit. The IMMI does not replace the

  13. Heading-vector navigation based on head-direction cells and path integration.

    Science.gov (United States)

    Kubie, John L; Fenton, André A

    2009-05-01

    Insect navigation is guided by heading vectors that are computed by path integration. Mammalian navigation models, on the other hand, are typically based on map-like place representations provided by hippocampal place cells. Such models compute optimal routes as a continuous series of locations that connect the current location to a goal. We propose a "heading-vector" model in which head-direction cells or their derivatives serve both as key elements in constructing the optimal route and as the straight-line guidance during route execution. The model is based on a memory structure termed the "shortcut matrix," which is constructed during the initial exploration of an environment when a set of shortcut vectors between sequential pairs of visited waypoint locations is stored. A mechanism is proposed for calculating and storing these vectors that relies on a hypothesized cell type termed an "accumulating head-direction cell." Following exploration, shortcut vectors connecting all pairs of waypoint locations are computed by vector arithmetic and stored in the shortcut matrix. On re-entry, when local view or place representations query the shortcut matrix with a current waypoint and goal, a shortcut trajectory is retrieved. Since the trajectory direction is in head-direction compass coordinates, navigation is accomplished by tracking the firing of head-direction cells that are tuned to the heading angle. Section 1 of the manuscript describes the properties of accumulating head-direction cells. It then shows how accumulating head-direction cells can store local vectors and perform vector arithmetic to perform path-integration-based homing. Section 2 describes the construction and use of the shortcut matrix for computing direct paths between any pair of locations that have been registered in the shortcut matrix. In the discussion, we analyze the advantages of heading-based navigation over map-based navigation. Finally, we survey behavioral evidence that nonhippocampal

  14. Comparison Between Several Integrase-defective Lentiviral Vectors Reveals Increased Integration of an HIV Vector Bearing a D167H Mutant

    Directory of Open Access Journals (Sweden)

    Muhammad Qamar Saeed

    2014-01-01

    Full Text Available HIV-1 derived vectors are among the most efficient for gene transduction in mammalian tissues. As the parent virus, they carry out vector genome insertion into the host cell chromatin. Consequently, their preferential integration in transcribed genes raises several conceptual and safety issues. To address part of these questions, HIV-derived vectors have been engineered to be nonintegrating. This was mainly achieved by mutating HIV-1 integrase at functional hotspots of the enzyme enabling the development of streamlined nuclear DNA circles functional for transgene expression. Few integrase mutant vectors have been successfully tested so far for gene transfer. They are cleared with time in mitotic cells, but stable within nondividing retina cells or neurons. Here, we compared six HIV vectors carrying different integrases, either wild type or with different mutations (D64V, D167H, Q168A, K186Q+Q214L+Q216L, and RRK262-264AAH shown to modify integrase enzymatic activity, oligomerization, or interaction with key cellular cofactor of HIV DNA integration as LEDGF/p75 or TNPO3. We show that these mutations differently affect the transduction efficiency as well as rates and patterns of integration of HIV-derived vectors suggesting their different processing in the nucleus. Surprisingly and most interestingly, we report that an integrase carrying the D167H substitution improves vector transduction efficiency and integration in both HEK-293T and primary CD34+ cells.

  15. Integrated emergency management in KKG

    International Nuclear Information System (INIS)

    Kluegel, J.U.; Plank, H.

    2007-01-01

    The development and introduction of emergency measures in Switzerland was mainly characterized by the evaluation of international experience and by systematic analysis of beyond-design basis accidents within the framework of plant-specific probabilistic safety analyses. As early as in the mid-eighties, the Swiss regulatory authority demanded that measures be taken against severe accidents, and periodically added more detailed requirements, most recently in 2000 when the introduction of Severe Accident Management Guidelines (SMAG) was demanded for power operation as well as operation in the non-power mode. The SMAG were introduced at the Goesgen nuclear power station within a project in the period between 2003 and 2005. For this purpose, a concept of integrated emergency management was developed which is based on updates of the proven emergency manual. One important aspect of this integrative concept is the distinction between preventive and mitigating procedures by defining appropriate criteria. The findings made in the implementation phase of the project include the realization that the introduction of procedures dealing with severe accidents also requires the ability to develop new ways of thinking and acting in accident management. This implies the awareness that procedures covering severe accidents must be applied much more flexibly and in the light of the situation than regulations covering fault conditions. Also possibilities to simulate severe accidents were created within the project both for the development of procedures and for training plant operators and members of the emergency staff. (orig.)

  16. INTEGRATED HSEQ MANAGEMENT SYSTEMS: DEVELOPMENTS AND TRENDS

    OpenAIRE

    Osmo Kauppila; Janne Härkönen; Seppo Väyrynen

    2015-01-01

    The integration of health and safety, environmental and quality (HSEQ) management systems has become a current topic in the 21st century, as the need for systems thinking has grown along with the number of management system standards. This study aims to map current developments and trends in integrated HSEQ management. Three viewpoints are taken: the current state of the main HSEQ management standards, research literature on integrated management systems (IMS), and a case study of an industry...

  17. Radioactive waste integrated management system

    Energy Technology Data Exchange (ETDEWEB)

    Song, D Y; Choi, S S; Han, B S [Atomic Creative Technology, Taejon (Korea, Republic of)

    2003-10-01

    In this paper, we present an integrated management system for radioactive waste, which can keep watch on the whole transporting process of each drum from nuclear power plant temporary storage house to radioactive waste storage house remotely. Our approach use RFID(Radio Frequency Identification) system, which can recognize the data information without touch, GSP system, which can calculate the current position precisely using the accurate time and distance measured from satellites, and the spread spectrum technology CDMA, which is widely used in the area of mobile communication.

  18. Radioactive waste integrated management system

    International Nuclear Information System (INIS)

    Song, D. Y.; Choi, S. S.; Han, B. S.

    2003-01-01

    In this paper, we present an integrated management system for radioactive waste, which can keep watch on the whole transporting process of each drum from nuclear power plant temporary storage house to radioactive waste storage house remotely. Our approach use RFID(Radio Frequency Identification) system, which can recognize the data information without touch, GSP system, which can calculate the current position precisely using the accurate time and distance measured from satellites, and the spread spectrum technology CDMA, which is widely used in the area of mobile communication

  19. Distribution Integrity Management Plant (DIMP)

    Energy Technology Data Exchange (ETDEWEB)

    Gonzales, Jerome F. [Los Alamos National Laboratory

    2012-05-07

    This document is the distribution integrity management plan (Plan) for the Los Alamos National Laboratory (LANL) Natural Gas Distribution System. This Plan meets the requirements of 49 CFR Part 192, Subpart P Distribution Integrity Management Programs (DIMP) for the LANL Natural Gas Distribution System. This Plan was developed by reviewing records and interviewing LANL personnel. The records consist of the design, construction, operation and maintenance for the LANL Natural Gas Distribution System. The records system for the LANL Natural Gas Distribution System is limited, so the majority of information is based on the judgment of LANL employees; the maintenance crew, the Corrosion Specialist and the Utilities and Infrastructure (UI) Civil Team Leader. The records used in this report are: Pipeline and Hazardous Materials Safety Administration (PHMSA) 7100.1-1, Report of Main and Service Line Inspection, Natural Gas Leak Survey, Gas Leak Response Report, Gas Leak and Repair Report, and Pipe-to-Soil Recordings. The specific elements of knowledge of the infrastructure used to evaluate each threat and prioritize risks are listed in Sections 6 and 7, Threat Evaluation and Risk Prioritization respectively. This Plan addresses additional information needed and a method for gaining that data over time through normal activities. The processes used for the initial assessment of Threat Evaluation and Risk Prioritization are the methods found in the Simple, Handy Risk-based Integrity Management Plan (SHRIMP{trademark}) software package developed by the American Pipeline and Gas Agency (APGA) Security and Integrity Foundation (SIF). SHRIMP{trademark} uses an index model developed by the consultants and advisors of the SIF. Threat assessment is performed using questions developed by the Gas Piping Technology Company (GPTC) as modified and added to by the SHRIMP{trademark} advisors. This Plan is required to be reviewed every 5 years to be continually refined and improved. Records

  20. Multi-disease data management system platform for vector-borne diseases.

    Directory of Open Access Journals (Sweden)

    Lars Eisen

    2011-03-01

    Full Text Available Emerging information technologies present new opportunities to reduce the burden of malaria, dengue and other infectious diseases. For example, use of a data management system software package can help disease control programs to better manage and analyze their data, and thus enhances their ability to carry out continuous surveillance, monitor interventions and evaluate control program performance.We describe a novel multi-disease data management system platform (hereinafter referred to as the system with current capacity for dengue and malaria that supports data entry, storage and query. It also allows for production of maps and both standardized and customized reports. The system is comprised exclusively of software components that can be distributed without the user incurring licensing costs. It was designed to maximize the ability of the user to adapt the system to local conditions without involvement of software developers. Key points of system adaptability include 1 customizable functionality content by disease, 2 configurable roles and permissions, 3 customizable user interfaces and display labels and 4 configurable information trees including a geographical entity tree and a term tree. The system includes significant portions of functionality that is entirely or in large part re-used across diseases, which provides an economy of scope as new diseases downstream are added to the system at decreased cost.We have developed a system with great potential for aiding disease control programs in their task to reduce the burden of dengue and malaria, including the implementation of integrated vector management programs. Next steps include evaluations of operational implementations of the current system with capacity for dengue and malaria, and the inclusion in the system platform of other important vector-borne diseases.

  1. CRISPR-Mediated Integration of Large Gene Cassettes Using AAV Donor Vectors

    Directory of Open Access Journals (Sweden)

    Rasmus O. Bak

    2017-07-01

    Full Text Available The CRISPR/Cas9 system has recently been shown to facilitate high levels of precise genome editing using adeno-associated viral (AAV vectors to serve as donor template DNA during homologous recombination (HR. However, the maximum AAV packaging capacity of ∼4.5 kb limits the donor size. Here, we overcome this constraint by showing that two co-transduced AAV vectors can serve as donors during consecutive HR events for the integration of large transgenes. Importantly, the method involves a single-step procedure applicable to primary cells with relevance to therapeutic genome editing. We use the methodology in primary human T cells and CD34+ hematopoietic stem and progenitor cells to site-specifically integrate an expression cassette that, as a single donor vector, would otherwise amount to a total of 6.5 kb. This approach now provides an efficient way to integrate large transgene cassettes into the genomes of primary human cells using HR-mediated genome editing with AAV vectors.

  2. INTEGRATED SUSTAINABLE MANGROVE FOREST MANAGEMENT

    Directory of Open Access Journals (Sweden)

    Cecep Kusmana

    2015-07-01

    Full Text Available Mangrove forest as a renewable resource must be managed based on sustainable basis in which the benefits of ecological, economic and social from the forest have to equity concern in achieving the optimum forest products and services in fulfill the needs of recent generation without destruction of future generation needs and that does not undesirable effects on the physical and social environment. This Sustainable Forest Management (SFM practices needs the supporting of sustainability in the development of social, economic and environment (ecological sounds simultaneously, it should be run by the proper institutional and regulations. In operational scale, SFM need integration in terms of knowledge, technical, consultative of stakeholders, coordination among sectors and other stakeholders, and considerations of ecological inter-relationship in which mangroves as an integral part of both a coastal ecosystem and a watershed (catchment area. Some tools have been developed to measure the performent of SFM, such as initiated by ITTO at 1992 and followed by Ministry of Forestry of Indonesia (1993, CIFOR (1995, LEI (1999, FSC (1999, etc., however, the true nuance of SFM’s performance is not easy to be measured. 

  3. Integrated Work Management: Overview, Course 31881

    Energy Technology Data Exchange (ETDEWEB)

    Simpson, Lewis Edward [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-06-30

    Integrated work management (IWM) is the process used for formally implementing the five-step process associated with integrated safety management (ISM) and integrated safeguards and security management (ISSM) at Los Alamos National Laboratory (LANL). IWM also directly supports the LANL Environmental Management System (EMS). IWM helps all workers and managers perform work safely and securely and in a manner that protects people, the environment, property, and the security of the nation. The IWM process applies to all work activities at LANL, from working in the office to designing experiments to assembling and detonating explosives. The primary LANL document that establishes and describes IWM requirements is Procedure (P) 300, Integrated Work Management.

  4. Managing focal fields of vector beams with multiple polarization singularities.

    Science.gov (United States)

    Han, Lei; Liu, Sheng; Li, Peng; Zhang, Yi; Cheng, Huachao; Gan, Xuetao; Zhao, Jianlin

    2016-11-10

    We explore the tight focusing behavior of vector beams with multiple polarization singularities, and analyze the influences of the number, position, and topological charge of the singularities on the focal fields. It is found that the ellipticity of the local polarization states at the focal plane could be determined by the spatial distribution of the polarization singularities of the vector beam. When the spatial location and topological charge of singularities have even-fold rotation symmetry, the transverse fields at the focal plane are locally linearly polarized. Otherwise, the polarization state becomes a locally hybrid one. By appropriately arranging the distribution of the polarization singularities in the vector beam, the polarization distributions of the focal fields could be altered while the intensity maintains unchanged.

  5. IDMT, Integrated Decommissioning Management Tools

    International Nuclear Information System (INIS)

    Alemberti, A.; Castagna, P.; Marsiletti, M.; Orlandi, S.; Perasso, L.; Susco, M.

    2005-01-01

    Nuclear Power Plant decommissioning requires a number of demolition activities related to civil works and systems as well as the construction of temporary facilities used for treatment and conditioning of the dismantled parts. The presence of a radiological, potentially hazardous, environment due to the specific configuration and history of the plant require a professional, expert and qualified approach approved by the national safety authority. Dismantling activities must be designed, planned and analysed in detail during an evaluation phase taking into account different scenarios generated by possible dismantling sequences and specific waste treatments to be implemented. The optimisation process of the activities becomes very challenging taking into account the requirement of the minimisation of the radiological impact on exposed workers and people during normal and accident conditions. While remote operated equipment, waste treatment and conditioning facilities may be designed taking into account this primary goal also a centralised management system and corresponding software tools have to be designed and operated in order to guarantee the fulfilment of the imposed limits as well as the traceability of wastes. Ansaldo Nuclear Division has been strongly involved in the development of a qualified and certified software environment to manage the most critical activities of a decommissioning project. The IDMT system (Integrated Decommissioning Management Tools) provide a set of stand alone user friendly applications able to work in an integrated configuration to guarantee waste identification, traceability during treatment and conditioning process as well as location and identification at the Final Repository site. Additionally, the system can be used to identify, analyse and compare different specific operating scenarios to be optimised in term of both economical and radiological considerations. The paper provides an overview of the different phases of

  6. Integrated Project Management System description

    International Nuclear Information System (INIS)

    1994-09-01

    The Integrated Program Management System (IPMS) Description is a ''working'' document that describes the work processes of the Uranium Mill Tailings Remedial Action Project Office (UMTRA) and IPMS Group. This document has undergone many revisions since the UMTRA Project began; this revision not only updates the work processes but more clearly explains the relationships between the Project Office, contractors, and other participants. The work process flow style has been revised to better describe Project work and the relationships of participants. For each work process, more background and guidance on ''why'' and ''what is expected'' is given. For example, a description of activity data sheets has been added in the work organization and the Project performance and reporting processes, as well as additional detail about the federal budget process and funding management and improved flow charts and explanations of cost and schedule management. A chapter has been added describing the Cost Reduction/Productivity Improvement Program. The Change Control Board (CCB) procedures (Appendix A) have been updated. Project critical issues meeting (PCIM) procedures have been added as Appendix B. Budget risk assessment meeting procedures have been added as Appendix C. These appendices are written to act as stand-alone documentation for each process. As the procedures are improved and updated, the documentation can be updated separately

  7. Integrating fire management analysis into land management planning

    Science.gov (United States)

    Thomas J. Mills

    1983-01-01

    The analysis of alternative fire management programs should be integrated into the land and resource management planning process, but a single fire management analysis model cannot meet all planning needs. Therefore, a set of simulation models that are analytically separate from integrated land management planning models are required. The design of four levels of fire...

  8. I-15 integrated corridor management system : project management plan.

    Science.gov (United States)

    2011-06-01

    The Project Management Plan (PMP) assists the San Diego ICM Team by defining a procedural framework for : management and control of the I-15 Integrated Corridor Management Demonstration Project, and development and : deployment of the ICM System. The...

  9. Managing IT Integration Risk in Acquisitions

    DEFF Research Database (Denmark)

    Henningsson, Stefan; Kettinger, William J.

    2016-01-01

    The article discusses a framework for evaluating risk of information technology (IT) integration in acquisitions. Topics include the use of the experience of serial acquirer Trelleborg AB to show the merits of the framework for managing the risk and to determine low-risk acquisitions......, the importance of managing IT integration risk, and various risk areas for acquisition IT integration....

  10. Integrated resource management of biomass

    International Nuclear Information System (INIS)

    Goodwin, E.R.

    1992-01-01

    An overview is presented of the use of biomass, with emphasis on peat, as an alternative energy source, from an integrated resource management perspective. Details are provided of the volume of the peat resource, economics of peat harvesting, and constraints to peat resource use, which mainly centre on its high water content. Use of waste heat to dry peat can increase the efficiency of peat burning for electric power generation, and new technologies such as gasification and turbo expanders may also find utilization. The burning or gasification of biomass will release no more carbon dioxide to the atmosphere than other fuels, has less sulfur content than solid fuels. The removal of peat reduces methane emissions and allows use of produced carbon dioxide for horticulture and ash for fertilizer, and creates space that may be used for forestry or agricultural biomass growth. 38 refs

  11. Integrated weed management in wheat

    International Nuclear Information System (INIS)

    Marwat, K.B.; Khan, M.A.; Nawab, K.; Khattak, A.M.

    2011-01-01

    The paper summarizes the results of an experiment conducted on wheat at Kohat, Khyber Pakhtunkhwa, Pakistan during winter 2004-05. Randomized complete block design with split-split-plot arrangement was used where wheat line and broadcast sowing were kept in main plots. Seed rates (100 and 150 kg ha-1) were assigned as sub-plots, while four herbicides (Topik, Isoproturon, Puma super and Buctril super) and weed check were assigned to sub-sub-plots. Results revealed that higher biological yield was recorded in line sowing. However, higher wheat seed rate decreased weed biomass and increased biological yield. Herbicides proved to be effective in decreasing weed biomass and enhancing grain yield and its contributing traits. It was suggested that line sowing in combination with higher seeding rate and Buctril super should be used in an integrated weed management fashion. However further studies are required to investigate various ranges of seeding rate and herbicides doses. (author)

  12. Integrated Computer System of Management in Logistics

    Science.gov (United States)

    Chwesiuk, Krzysztof

    2011-06-01

    This paper aims at presenting a concept of an integrated computer system of management in logistics, particularly in supply and distribution chains. Consequently, the paper includes the basic idea of the concept of computer-based management in logistics and components of the system, such as CAM and CIM systems in production processes, and management systems for storage, materials flow, and for managing transport, forwarding and logistics companies. The platform which integrates computer-aided management systems is that of electronic data interchange.

  13. Integrated Strategies for the Control and Prevention of Dengue Vectors with Particular Reference to Aedes aegypti

    Directory of Open Access Journals (Sweden)

    Asghar Abbas

    2014-01-01

    Full Text Available Dengue fever (DF is one of the most threatening vector borne diseases, affecting both humans and animals, causing severe epidemics and has brought the world to take serious steps for its control and prevention. DF is a viral disease transmitted by Aedes mosquitoes. Unfortunately, due to unavailability of vaccine and lack of effective treatment, emphasis is given on its vector control. The only option left for its eradication is to restrict mosquito breeding. This can be achieved by chemical, biological and environment management methods. Use of botanicals is also an alternate and probably most effective approach for controlling DF vector. Community based eradication campaigns including educating people about its prevention and control meseaures and personal prophylaxis also play a vital role to prevent its occurrence. Likewise, use of nanotechnology and micro-emulsion, use of pheromones, insect sterilization techniques has also shown promising results in vector control. Utilization of only one method cannot control this dangerous disease but combination of all above interventions, discussed in the present paper, may prevent the DF vector and ultimately might help in the eradication programs of this disease.

  14. Considerations on Integrating Risk and Quality Management

    Directory of Open Access Journals (Sweden)

    Maria POPESCU

    2011-03-01

    Full Text Available This paper aims to highlight the links between risk management and quality management and to study the possibility of their integrated approach. The study reviews the evolution of risk approach within organizations and stresses the need to increase the effectiveness of this approach by incorporating risk management methodology in the quality management system. Starting from this idea, the authors present the current state of risk approach into quality management, basic rules of integrated quality-risk management and major difficulties which may arise in the implementation of integrated quality–risk systems.

  15. A Performance Management Initiative for Local Health Department Vector Control Programs.

    Science.gov (United States)

    Gerding, Justin; Kirshy, Micaela; Moran, John W; Bialek, Ron; Lamers, Vanessa; Sarisky, John

    2016-01-01

    Local health department (LHD) vector control programs have experienced reductions in funding and capacity. Acknowledging this situation and its potential effect on the ability to respond to vector-borne diseases, the U.S. Centers for Disease Control and Prevention and the Public Health Foundation partnered on a performance management initiative for LHD vector control programs. The initiative involved 14 programs that conducted a performance assessment using the Environmental Public Health Performance Standards. The programs, assisted by quality improvement (QI) experts, used the assessment results to prioritize improvement areas that were addressed with QI projects intended to increase effectiveness and efficiency in the delivery of services such as responding to mosquito complaints and educating the public about vector-borne disease prevention. This article describes the initiative as a process LHD vector control programs may adapt to meet their performance management needs. This study also reviews aggregate performance assessment results and QI projects, which may reveal common aspects of LHD vector control program performance and priority improvement areas. LHD vector control programs interested in performance assessment and improvement may benefit from engaging in an approach similar to this performance management initiative.

  16. Status of pesticide management in the practice of vector control: a global survey in countries at risk of malaria or other major vector-borne diseases

    NARCIS (Netherlands)

    Berg, van den H.; Hii, J.; Soares, A.; Mnzava, A.; Ameneshewa, B.; Dash, A.P.; Ejov, M.; Tan, S.H.; Matthews, G.; Yadav, R.S.; Zaim, M.

    2011-01-01

    Background: It is critical that vector control pesticides are used for their acceptable purpose without causing adverse effects on health and the environment. This paper provides a global overview of the current status of pesticides management in the practice of vector control. Methods: A

  17. Information Security Management - Part Of The Integrated Management System

    Science.gov (United States)

    Manea, Constantin Adrian

    2015-07-01

    The international management standards allow their integrated approach, thereby combining aspects of particular importance to the activity of any organization, from the quality management systems or the environmental management of the information security systems or the business continuity management systems. Although there is no national or international regulation, nor a defined standard for the Integrated Management System, the need to implement an integrated system occurs within the organization, which feels the opportunity to integrate the management components into a cohesive system, in agreement with the purpose and mission publicly stated. The issues relating to information security in the organization, from the perspective of the management system, raise serious questions to any organization in the current context of electronic information, reason for which we consider not only appropriate but necessary to promote and implement an Integrated Management System Quality - Environment - Health and Operational Security - Information Security

  18. Integrated Procurement Management System, Version II

    Science.gov (United States)

    Collier, L. J.

    1985-01-01

    Integrated Procurement Management System, Version II (IPMS II) is online/ batch system for collecting developing, managing and disseminating procurementrelated data at NASA Johnson Space Center. Portions of IPMS II adaptable to other procurement situations.

  19. Pupal productivity of dengue vectors in Kolkata, India: implications for vector management

    Directory of Open Access Journals (Sweden)

    Soumyajit Banerjee

    2013-01-01

    Interpretation & conclusions: Pupal productivity of Aedes mosquitoes in Kolkata differed in terms of the type of the larval habitats with the immature density affecting the body size of the adults. This habitat-based study is a pioneer effort considering Kolkata and calls for a management plan for source reduction of these habitats to minimize Aedes mosquitoes and thus potential risk of dengue.

  20. VISPA2: a scalable pipeline for high-throughput identification and annotation of vector integration sites.

    Science.gov (United States)

    Spinozzi, Giulio; Calabria, Andrea; Brasca, Stefano; Beretta, Stefano; Merelli, Ivan; Milanesi, Luciano; Montini, Eugenio

    2017-11-25

    Bioinformatics tools designed to identify lentiviral or retroviral vector insertion sites in the genome of host cells are used to address the safety and long-term efficacy of hematopoietic stem cell gene therapy applications and to study the clonal dynamics of hematopoietic reconstitution. The increasing number of gene therapy clinical trials combined with the increasing amount of Next Generation Sequencing data, aimed at identifying integration sites, require both highly accurate and efficient computational software able to correctly process "big data" in a reasonable computational time. Here we present VISPA2 (Vector Integration Site Parallel Analysis, version 2), the latest optimized computational pipeline for integration site identification and analysis with the following features: (1) the sequence analysis for the integration site processing is fully compliant with paired-end reads and includes a sequence quality filter before and after the alignment on the target genome; (2) an heuristic algorithm to reduce false positive integration sites at nucleotide level to reduce the impact of Polymerase Chain Reaction or trimming/alignment artifacts; (3) a classification and annotation module for integration sites; (4) a user friendly web interface as researcher front-end to perform integration site analyses without computational skills; (5) the time speedup of all steps through parallelization (Hadoop free). We tested VISPA2 performances using simulated and real datasets of lentiviral vector integration sites, previously obtained from patients enrolled in a hematopoietic stem cell gene therapy clinical trial and compared the results with other preexisting tools for integration site analysis. On the computational side, VISPA2 showed a > 6-fold speedup and improved precision and recall metrics (1 and 0.97 respectively) compared to previously developed computational pipelines. These performances indicate that VISPA2 is a fast, reliable and user-friendly tool for

  1. Assessment of Integration-defective HIV-1 and EIAV Vectors In Vitro and In Vivo

    Directory of Open Access Journals (Sweden)

    Scott Ellis

    2012-01-01

    Full Text Available The interest in integrase-defective lentiviral vectors (IDLVs stems from their potential advantage of large cloning capacity and broad cell tropism while avoiding the possibility of insertional mutagenesis. Here, we directly compared the transducing potential of IDLVs based on the equine infectious anemia virus (EIAV to the more commonly described HIV-1 IDLVs. IDLVs were constructed by introducing equivalent single/triple mutations into the integrase catalytic triad. We show that both the single and the triple mutant HIV-1 IDLVs transduce the PC12 cells, but not the C2C12 cells, with similar efficiency to their parental HIV-1 vector. In contrast, the single and triple EIAV IDLVs did not efficiently transduce either differentiated cell line. Moreover, this HIV-1 IDLV-mediated expression was independent of any residual integration activity because reporter expression was lost when cell cycling was restored. Four weeks following stereotactic administration into adult rat brains, only the single HIV-1 IDLV mutant displayed a comparable transduction profile to the parental HIV-1 vector. In contrast, neither EIAV IDLV mutants showed significant reporter gene expression. This work indicates that the transducing potential of IDLVs appears to depend not only on the choice of integrase mutation and type of target cell, but also on the nature of the lentiviral vector.

  2. Integrated management of childhood illness

    Directory of Open Access Journals (Sweden)

    1997-01-01

    Full Text Available Millones de defunciones en niños menores de 5 años se podrían prevenir en países en desarrollo si se aplicaran las medidas de control y los tratamientos eficaces que se usan normalmente en países desarrollados. Conscientes de la necesidad de hacer frente a las principales causas de enfermedad y muerte en la infancia (infecciones respiratorias agudas, enfermedades diarreicas, desnutrición, malaria y enfermedades prevenibles por medio de la vacunación mediante una iniciativa global, la OMS y el UNICEF han desarrollado una estrategia conocida por Atención Integrada de las Enfermedades Prevalentes de la Infancia (Integrated Management of Childhood Illness, IMCI. Sus oficinas regionales para las Américas, que son la OPS y el UNICEF-TACRO, han aceptado los objetivos y actividades descritos en el presente informe a fin de reorientar su labor y dirigirla hacia el mejoramiento del estado de salud infantil en este hemisferio.

  3. Phase portraits of cubic polynomial vector fields of Lotka-Volterra type having a rational first integral of degree 2

    International Nuclear Information System (INIS)

    Cairo, Laurent; Llibre, Jaume

    2007-01-01

    We classify all the global phase portraits of the cubic polynomial vector fields of Lotka-Volterra type having a rational first integral of degree 2. For such vector fields there are exactly 28 different global phase portraits in the Poincare disc up to a reversal of sense of all orbits

  4. Integrated Work Management: Preparer, Course 31883

    Energy Technology Data Exchange (ETDEWEB)

    Simpson, Lewis Edward [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-08-07

    The preparer (also called the “planner”) plays a key role in the integrated work management (IWM) process at Los Alamos National Laboratory (LANL). This course, Integrated Work Management: Preparer (COURSE 31883), describes the IWM roles and responsibilities of the preparer. This course also discusses IWM requirements that must be met by the preparer.

  5. The derivation of vector magnetic fields from Stokes profiles - Integral versus least squares fitting techniques

    Science.gov (United States)

    Ronan, R. S.; Mickey, D. L.; Orrall, F. Q.

    1987-01-01

    The results of two methods for deriving photospheric vector magnetic fields from the Zeeman effect, as observed in the Fe I line at 6302.5 A at high spectral resolution (45 mA), are compared. The first method does not take magnetooptical effects into account, but determines the vector magnetic field from the integral properties of the Stokes profiles. The second method is an iterative least-squares fitting technique which fits the observed Stokes profiles to the profiles predicted by the Unno-Rachkovsky solution to the radiative transfer equation. For sunspot fields above about 1500 gauss, the two methods are found to agree in derived azimuthal and inclination angles to within about + or - 20 deg.

  6. Integrated Co-management of Lakes through Beach Management Units

    OpenAIRE

    Goverment of Uganda; Department for International Development (DFID) of the UK Government

    2007-01-01

    Metadata only record In 1999, the Integrated Co-management of Lakes through Beach Management Units project was started in an effort to implement a new approach to the management of lake resources in Uganda. The main components of this plan involved decentralization, local community management, and improving the livelihood of the poor. In order to finance the management of these areas, the Beach Management Units (BMU's) are charging user fees to those individuals who obtain benefit from the...

  7. INTEGRATIVE AUGMENTATION OF STANDARDIZED MANAGEMENT SYSTEMS

    Directory of Open Access Journals (Sweden)

    Stanislav Karapetrovic

    2008-03-01

    Full Text Available The development, features and integrating abilities of different international standards related to management systems are discussed. A group of such standards that augment the performance of quality management systems in organizations is specifically focused on. The concept, characteristics and an illustrative example of one augmenting standard, namely ISO 10001, are addressed. Integration of standardized augmenting systems, both by themselves and within the overall management system, is examined. It is argued that, in research and practice alike, integrative augmentation represents the future of standardized quality and other management systems.

  8. Waste management - an integral part of environmental management systems

    Energy Technology Data Exchange (ETDEWEB)

    Hamm, Ulrich

    1998-12-01

    To consider waste as a resource instead of an annoyance with which the management has to cope with, has become an unavoidable task for modern managers. The task the management has to take to secure competitiveness in an environment of rising complexity of production processes and further increasing legal requirements, is to manage waste as much as other recourses are managed. Waste has to be considered an aspect of planning and decision process just as business plans or logistics are. Main themes discussed in this publication comprise waste management, implementation of waste management as an integral part of environmental management systems, and management approach to waste - the results. 4 figs.

  9. Differential Galois theory and non-integrability of planar polynomial vector fields

    Science.gov (United States)

    Acosta-Humánez, Primitivo B.; Lázaro, J. Tomás; Morales-Ruiz, Juan J.; Pantazi, Chara

    2018-06-01

    We study a necessary condition for the integrability of the polynomials vector fields in the plane by means of the differential Galois Theory. More concretely, by means of the variational equations around a particular solution it is obtained a necessary condition for the existence of a rational first integral. The method is systematic starting with the first order variational equation. We illustrate this result with several families of examples. A key point is to check whether a suitable primitive is elementary or not. Using a theorem by Liouville, the problem is equivalent to the existence of a rational solution of a certain first order linear equation, the Risch equation. This is a classical problem studied by Risch in 1969, and the solution is given by the "Risch algorithm". In this way we point out the connection of the non integrability with some higher transcendent functions, like the error function.

  10. A Neural Path Integration Mechanism for Adaptive Vector Navigation in Autonomous Agents

    DEFF Research Database (Denmark)

    Goldschmidt, Dennis; Dasgupta, Sakyasingha; Wörgötter, Florentin

    2015-01-01

    Animals show remarkable capabilities in navigating their habitat in a fully autonomous and energy-efficient way. In many species, these capabilities rely on a process called path integration, which enables them to estimate their current location and to find their way back home after long-distance...... of autonomous agent navigation, but it also reproduces various aspects of animal navigation. Finally, we discuss how the proposed path integration mechanism may be used as a scaffold for spatial learning in terms of vector navigation.......Animals show remarkable capabilities in navigating their habitat in a fully autonomous and energy-efficient way. In many species, these capabilities rely on a process called path integration, which enables them to estimate their current location and to find their way back home after long...

  11. Integrated management of waterbirds: Beyond the conventional

    Science.gov (United States)

    Erwin, R.M.; Parsons, Katharine C.; Brown, Stephen C.; Erwin, R. Michael; Czech, Helen A.; Coulson, John C.

    2002-01-01

    Integrated waterbird management over the past few decades has implicitly referred to methods for managing wetlands that usually attempt to enhance habitat for taxonomic groups such as shorebirds and wading birds, in addition to waterfowl, the traditional focus group. Here I describe five elements of integration in management: taxonomic, spatial, temporal, population and habitat, and multiple-use management objectives. Spatial integration simply expands the scale of management concern. Rather than emphasizing management on a very limited number of impoundments or wetlands in small refuges or wildlife management areas, the vision is beginning to shift to connectivity within larger landscapes on the order of many square kilometers as telemetry data on daily and seasonal movements for many species become available. Temporal integration refers to the potential for either simultaneous management for waterbirds and commercial 'crops' (e.g., crayfish and rice) or for temporally-staggered management such as row crop production in spring-summer growing seasons and waterbird management on fallow fields in the non-growing (winter) season. Integrating population dynamics with habitats has become a major research focus over the past decade. Identifying which wetlands are ?sources? or ?sinks? for specific populations provides managers with critical information about effective management. Further, the applications of spatially explicit population models place heavy demands on researchers to identify use patterns for breeding and dispersing individuals by age, sex, and reproductive class. Population viability analysis models require much the same information. Finally, multiple-use management integration refers to trying to optimize the uses of wetlands, when only one (perhaps secondary) use may include waterbird management. Depending upon the ownership and primary land use of a particular parcel of land containing wetlands and/or water bodies, managing for waterbirds may be an

  12. Construction of a New Phage Integration Vector pFIV-Val for Use in Different Francisella Species

    Directory of Open Access Journals (Sweden)

    Hana Tlapák

    2018-03-01

    Full Text Available We recently identified and described a putative prophage on the genomic island FhaGI-1 located within the genome of Francisella hispaniensis AS02-814 (F. tularensis subsp. novicida-like 3523. In this study, we constructed two variants of a Francisella phage integration vector, called pFIV1-Val and pFIV2-Val (Francisella Integration Vector-tRNAVal-specific, using the attL/R-sites and the site-specific integrase (FN3523_1033 of FhaGI-1, a chloramphenicol resistance cassette and a sacB gene for counter selection of transformants against the vector backbone. We inserted the respective sites and genes into vector pUC57-Kana to allow for propagation in Escherichia coli. The constructs generated a circular episomal form in E. coli which could be used to transform Francisella spp. where FIV-Val stably integrated site specifically into the tRNAVal gene of the genome, whereas pUC57-Kana is lost due to counter selection. Functionality of the new vector was demonstrated by the successfully complementation of a Francisella mutant strain. The vectors were stable in vitro and during host-cell infection without selective pressure. Thus, the vectors can be applied as a further genetic tool in Francisella research, expanding the present genetic tools by an integrative element. This new element is suitable to perform long-term experiments with different Francisella species.

  13. Export channel pricing management for integrated solutions

    OpenAIRE

    Roine, Henna; Sainio, Liisa-Maija; Saarenketo, Sami

    2012-01-01

    This article studies systems integrators' export channel pricing management for integrated solutions. We find support from our empirical case study for the notion that a systems integrator's export channel pricing strategy is multidimensional and dependent on international pricing environment and partner characteristics and that export partnerships have unique implications on a systems integrator's pricing process. The results show that giving up pricing control in export channel context may ...

  14. Integrated solid waste management in Germany

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-07-01

    This report covers Germany`s experience with integrated solid waste management programs. The municipal solid waste practices of four cities include practices and procedures that waste facility managers with local or state governments may consider for managing their own day-to-day operations.

  15. Integrating the autonomous subsystems management process

    Science.gov (United States)

    Ashworth, Barry R.

    1992-01-01

    Ways in which the ranking of the Space Station Module Power Management and Distribution testbed may be achieved and an individual subsystem's internal priorities may be managed within the complete system are examined. The application of these results in the integration and performance leveling of the autonomously managed system is discussed.

  16. Integrated Work Management: PIC, Course 31884

    Energy Technology Data Exchange (ETDEWEB)

    Simpson, Lewis Edward [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-09-08

    The person-in-charge (PIC) plays a key role in the integrated work management (IWM) process at Los Alamos National Laboratory (LANL, or the Laboratory) because the PIC is assigned responsibility and authority by the responsible line manager (RLM) for the overall validation, coordination, release, execution, and closeout of a work activity in accordance with IWM. This course, Integrated Work Management: PIC (Course 31884), describes the PIC’s IWM roles and responsibilities. This course also discusses IWM requirements that the PIC must meet. For a general overview of the IWM process, see self-study Course 31881, Integrated Work Management: Overview. For instruction on the preparer’s role, see self-study Course 31883, Integrated Work Management: Preparer.

  17. Stable integration of recombinant adeno-associated virus vector genomes after transduction of murine hematopoietic stem cells.

    Science.gov (United States)

    Han, Zongchao; Zhong, Li; Maina, Njeri; Hu, Zhongbo; Li, Xiaomiao; Chouthai, Nitin S; Bischof, Daniela; Weigel-Van Aken, Kirsten A; Slayton, William B; Yoder, Mervin C; Srivastava, Arun

    2008-03-01

    We previously reported that among single-stranded adeno-associated virus (ssAAV) vectors, serotypes 1 through 5, ssAAV1 is the most efficient in transducing murine hematopoietic stem cells (HSCs), but viral second-strand DNA synthesis remains a rate-limiting step. Subsequently, using double-stranded, self-complementary AAV (scAAV) vectors, serotypes 7 through 10, we observed that scAAV7 vectors also transduce murine HSCs efficiently. In the present study, we used scAAV1 and scAAV7 shuttle vectors to transduce HSCs in a murine bone marrow serial transplant model in vivo, which allowed examination of the AAV proviral integration pattern in the mouse genome, as well as recovery and nucleotide sequence analyses of AAV-HSC DNA junction fragments. The proviral genomes were stably integrated, and integration sites were localized to different mouse chromosomes. None of the integration sites was found to be in a transcribed gene, or near a cellular oncogene. None of the animals, monitored for up to 1 year, exhibited pathological abnormalities. Thus, AAV proviral integration-induced risk of oncogenesis was not found in our study, which provides functional confirmation of stable transduction of self-renewing multipotential HSCs by scAAV vectors as well as promise for the use of these vectors in the potential treatment of disorders of the hematopoietic system.

  18. Insecticide resistance in vector Chagas disease: evolution, mechanisms and management.

    Science.gov (United States)

    Mougabure-Cueto, Gastón; Picollo, María Inés

    2015-09-01

    Chagas disease is a chronic parasitic infection restricted to America. The disease is caused by the protozoa Trypanosoma cruzi, which is transmitted to human through the feces of infected triatomine insects. Because no treatment is available for the chronic forms of the disease, vector chemical control represents the best way to reduce the incidence of the disease. Chemical control has been based principally on spraying dwellings with insecticide formulations and led to the reduction of triatomine distribution and consequent interruption of disease transmission in several areas from endemic region. However, in the last decade it has been repeatedly reported the presence triatomnes, mainly Triatoma infestans, after spraying with pyrethroid insecticides, which was associated to evolution to insecticide resistance. In this paper the evolution of insecticide resistance in triatomines is reviewed. The insecticide resistance was detected in 1970s in Rhodnius prolixus and 1990s in R. prolixus and T. infestans, but not until the 2000s resistance to pyrthroids in T. infestans associated to control failures was described in Argentina and Bolivia. The main resistance mechanisms (i.e. enhanced metabolism, altered site of action and reduced penetration) were described in the T. infestans resistant to pyrethrods. Different resistant profiles were demonstrated suggesting independent origin of the different resistant foci of Argentina and Bolivia. The deltamethrin resistance in T. infestans was showed to be controlled by semi-dominant, autosomally inherited factors. Reproductive and developmental costs were also demonstrated for the resistant T. infestans. A discussion about resistance and tolerance concepts and the persistence of T. infestans in Gran Chaco region are presented. In addition, theoretical concepts related to toxicological, evolutionary and ecological aspects of insecticide resistance are discussed in order to understand the particular scenario of pyrethroid

  19. Transaction management with integrity checking

    DEFF Research Database (Denmark)

    Martinenghi, Davide; Christiansen, Henning

    2005-01-01

    Database integrity constraints, understood as logical conditions that must hold for any database state, are not fully supported by current database technology. It is typically up to the database designer and application programmer to enforce integrity via triggers or tests at the application level....... 2.~In concurrent database systems, besides the traditional correctness criterion, the execution schedule must ensure that the different transactions can overlap in time without destroying the consistency requirements tested by other, concurrent transactions....

  20. Global challenges in integrated coastal zone management

    DEFF Research Database (Denmark)

    integration of data and information in policy and management, combining expertise from nature and social science, to reach a balanced and sustainable development of the coastal zone. This important book comprises the proceedings of The International Symposium on Integrated Coastal Zone Management, which took....../mitigation to change in coastal systems Coastal governance Linking science and management Comprising a huge wealth of information, this timely and well-edited volume is essential reading for all those involved in coastal zone management around the globe. All libraries in research establishments and universities where...

  1. I-15 integrated corridor management : system requirements.

    Science.gov (United States)

    2011-07-01

    This document is intended as a listing and discussion of the Requirements for the I-15 Integrated Corridor Management System : (ICMS) Demonstration Project in San Diego. This document describes what the system is to do (the functional requirements), ...

  2. Factors influencing implementation of integrated management of ...

    African Journals Online (AJOL)

    intern

    implementation of health facility based Integrated Management of Childhood Illness ... community-owned resource persons (CORPs) to provide health education to care ... differing coverage of basic essential services such safe water supply, ...

  3. AN ASSESSMENT OF THE INTEGRATED PEST MANAGEMENT ...

    African Journals Online (AJOL)

    Integrated Pest Management Collaborative Research Support Program) has been applying a farmer participatory IPM strategy at on-farm research sites in eastern Uganda since 1995. Following five years of project implementation an evaluation ...

  4. Integrated Data for Improved Asset Management

    Science.gov (United States)

    2016-05-26

    The objective of this research is to demonstrate the potential benefits for agency-wide data integration for VDOT asset management. This objective is achieved through an example application that requires information distributed across multiple databa...

  5. Integrated management systems in the nuclear field

    International Nuclear Information System (INIS)

    Beckmerhagen, I.A.; Berg, H.P.; Karapetrovic, S.V.; Willborn, W.O.

    2005-01-01

    In the last years several internationally accepted standards such as the ISO 9000 and ISO 14000 series and other function-specific management systems standards have been developed. At the same time, it has become imperative for organisations to continuously improve their overall quality, environmental and safety performance. Therefore, the need to create integrated management systems is of growing importance to enable an easier handling of the different management systems. This paper has two main objectives. The first one is to address the key issues in the underlying theory of integrated management systems including benefits and limits, the second one is to illustrate the importance of an integrated (in particular safety) management system and the experience feedback providing examples from different areas and different organisations in the nuclear field. (orig.)

  6. EasyCloneMulti: A Set of Vectors for Simultaneous and Multiple Genomic Integrations in Saccharomyces cerevisiae

    DEFF Research Database (Denmark)

    Maury, Jerome; Germann, Susanne Manuela; Jacobsen, Simo Abdessamad

    2016-01-01

    Saccharomyces cerevisiae is widely used in the biotechnology industry for production of ethanol, recombinant proteins, food ingredients and other chemicals. In order to generate highly producing and stable strains, genome integration of genes encoding metabolic pathway enzymes is the preferred...... of integrative vectors, EasyCloneMulti, that enables multiple and simultaneous integration of genes in S. cerevisiae. By creating vector backbones that combine consensus sequences that aim at targeting subsets of Ty sequences and a quickly degrading selective marker, integrations at multiple genomic loci...... and a range of expression levels were obtained, as assessed with the green fluorescent protein (GFP) reporter system. The EasyCloneMulti vector set was applied to balance the expression of the rate-controlling step in the β-alanine pathway for biosynthesis of 3-hydroxypropionic acid (3HP). The best 3HP...

  7. Integrated Solution Support System for Water Management

    NARCIS (Netherlands)

    Kassahun, A.; Blind, M.; Krause, A.U.M.; Roosenschoon, O.R.

    2008-01-01

    Solving water management problems involves technical, social, economic, political and legal challenges and thus requires an integrated approach involving people from different backgrounds and roles. The integrated approach has been given a prominent role within the European Union¿s Water Framework

  8. Integrating Sustainable Development into Operations Management Courses

    Science.gov (United States)

    Fredriksson, Peter; Persson, Magnus

    2011-01-01

    Purpose: It is widely acknowledged that aspects of sustainable development (SD) should be integrated into higher level operations management (OM) education. The aim of the paper is to outline the experiences gained at Chalmers University of Technology in Sweden from integrating aspects of SD into OM courses. Design/methodology/approach: The paper…

  9. Business process management and IT management: The missing integration

    DEFF Research Database (Denmark)

    Rahimi, Fatemeh; Møller, Charles; Hvam, Lars

    2016-01-01

    of IT on process innovations, the association between business process management and IT management is under-explored. Drawing on a literature analysis of the capabilities of business process and IT governance frameworks and findings from a case study, we propose the need for horizontal integration between the two......The importance of business processes and the centrality of IT to contemporary organizations' performance calls for a specific focus on business process management and IT management. Despite the wide scope of business process management covering both business and IT domains, and the profound impact...... management functions to enable strategic and operational business - IT alignment. We further argue that the role of IT in an organization influences the direction of integration between the two functions and thus the choice of integration mechanisms. Using case study findings, we propose...

  10. Insights from agriculture for the management of insecticide resistance in disease vectors.

    Science.gov (United States)

    Sternberg, Eleanore D; Thomas, Matthew B

    2018-04-01

    Key to contemporary management of diseases such as malaria, dengue, and filariasis is control of the insect vectors responsible for transmission. Insecticide-based interventions have contributed to declines in disease burdens in many areas, but this progress could be threatened by the emergence of insecticide resistance in vector populations. Insecticide resistance is likewise a major concern in agriculture, where insect pests can cause substantial yield losses. Here, we explore overlaps between understanding and managing insecticide resistance in agriculture and in public health. We have used the Global Plan for Insecticide Resistance Management in malaria vectors, developed under the auspices of the World Health Organization Global Malaria Program, as a framework for this exploration because it serves as one of the few cohesive documents for managing a global insecticide resistance crisis. Generally, this comparison highlights some fundamental differences between insect control in agriculture and in public health. Moreover, we emphasize that the success of insecticide resistance management strategies is strongly dependent on the biological specifics of each system. We suggest that the biological, operational, and regulatory differences between agriculture and public health limit the wholesale transfer of knowledge and practices from one system to the other. Nonetheless, there are some valuable insights from agriculture that could assist in advancing the existing Global Plan for Insecticide Resistance Management framework.

  11. Partnering and integrated supply management

    DEFF Research Database (Denmark)

    Bjarnø, Ole-Christian; Olsen, Anders; Thyssen, Mikael

    2003-01-01

    for strategic management of collaborative relationships on a line with the purchasing perspectives offered by Supply Chain Management. Based on a study of the literature and an in-depth case study carried out within a large Scandinavian contractor, this article gives a proposal for how Partnering can...... be supported by strategic purchasing, with the aim of achieving strategic Partnering. The contribution of this article is thus the development of a new purchasing perspective within Construction Supply Chain Management.......Developments in the construction industry, with a lack of productivity increases compared to manufacturing industry in general, have amongst other things led to the use of Partnering, which is a form of collaboration which attempts to counteract the distrust and the sub-optimisation which...

  12. Managing harvest and habitat as integrated components

    Science.gov (United States)

    Osnas, Erik; Runge, Michael C.; Mattsson, Brady J.; Austin, Jane E.; Boomer, G. S.; Clark, R. G.; Devers, P.; Eadie, J. M.; Lonsdorf, E. V.; Tavernia, Brian G.

    2014-01-01

    In 2007, several important initiatives in the North American waterfowl management community called for an integrated approach to habitat and harvest management. The essence of the call for integration is that harvest and habitat management affect the same resources, yet exist as separate endeavours with very different regulatory contexts. A common modelling framework could help these management streams to better understand their mutual effects. Particularly, how does successful habitat management increase harvest potential? Also, how do regional habitat programmes and large-scale harvest strategies affect continental population sizes (a metric used to express habitat goals)? In the ensuing five years, several projects took on different aspects of these challenges. While all of these projects are still on-going, and are not yet sufficiently developed to produce guidance for management decisions, they have been influential in expanding the dialogue and producing some important emerging lessons. The first lesson has been that one of the more difficult aspects of integration is not the integration across decision contexts, but the integration across spatial and temporal scales. Habitat management occurs at local and regional scales. Harvest management decisions are made at a continental scale. How do these actions, taken at different scales, combine to influence waterfowl population dynamics at all scales? The second lesson has been that consideration of the interface of habitat and harvest management can generate important insights into the objectives underlying the decision context. Often the objectives are very complex and trade-off against one another. The third lesson follows from the second – if an understanding of the fundamental objectives is paramount, there is no escaping the need for a better understanding of human dimensions, specifically the desires of hunters and nonhunters and the role they play in conservation. In the end, the compelling question is

  13. INTEGRATED HSEQ MANAGEMENT SYSTEMS: DEVELOPMENTS AND TRENDS

    Directory of Open Access Journals (Sweden)

    Osmo Kauppila

    2015-06-01

    Full Text Available The integration of health and safety, environmental and quality (HSEQ management systems has become a current topic in the 21st century, as the need for systems thinking has grown along with the number of management system standards. This study aims to map current developments and trends in integrated HSEQ management. Three viewpoints are taken: the current state of the main HSEQ management standards, research literature on integrated management systems (IMS, and a case study of an industry-led HSEQ cluster in Northern Finland. The results demonstrate that some of the most prominent current trends are the harmonization of the high level structure of management systems by ISO, the evaluation of IMS, accounting for the supply chain in HSEQ issues, and sustainability and risk management. The results of the study can be used by practitioners to get a view of the current state of HSEQ management systems and their integration, and by researchers to seek out potential directions for HSEQ and IMS related research.

  14. Integrated pest management - an overview and update

    Science.gov (United States)

    Thomas D. Landis; R. Kasten Dumroese

    2014-01-01

    Integrated pest management, better known as IPM, is a familiar term for those of us working in forest, conservation, and native plant nurseries. An almost synonymous concept is "holistic pest management" that has been the topic of chapters in recent Agriculture Handbooks that would be useful to growers of native plants (see Landis and others 2009; Landis and...

  15. Integration of operational research and environmental management

    NARCIS (Netherlands)

    Bloemhof - Ruwaard, J.M.

    1996-01-01


    The subject of this thesis is the integration of Operational Research and Environmental Management. Both sciences play an important role in the research of environmental issues. Part I describes a framework for the interactions between Operational Research and Environmental Management.

  16. Integrated Approach to User Account Management

    Science.gov (United States)

    Kesselman, Glenn; Smith, William

    2007-01-01

    IT environments consist of both Windows and other platforms. Providing user account management for this model has become increasingly diffi cult. If Microsoft#s Active Directory could be enhanced to extend a W indows identity for authentication services for Unix, Linux, Java and Macintosh systems, then an integrated approach to user account manag ement could be realized.

  17. Characteristics of malaria vector breeding habitats in Sri Lanka: relevance for environmental management

    DEFF Research Database (Denmark)

    Hoek, Wim van der; Amerasinghe, F P; Konradsen, F

    1998-01-01

    , potential secondary vectors, were characterized by site, exposure to sunlight, substratum, turbidity of the water, presence of vegetation, and presence of fauna. Availability of pools of stagnant water in the stream near the village and along the edge of the village tank was highly predictive for presence......In and around a village in the Anuradhapura District of Sri Lanka anopheline larvae were sampled from July 1994 to April 1996 in all surface water bodies. Samples positive for Anopheles culicifacies, the established vector of malaria in Sri Lanka, and for An. barbirostris, An. vagus, and An. varuna...... clear water pools, was able to exploit habitats that were shaded and contained turbid water. Environmental management interventions to control An. culicifacies breeding have to take into account that the secondary vectors of malaria exploit other habitats and would not be affected by the interventions....

  18. Implementing Integrated River Basin Management in China

    Directory of Open Access Journals (Sweden)

    Dorri G. J. te Boekhorst

    2010-06-01

    Full Text Available This paper examines the role of the World Wildlife Fund for Nature China as policy entrepreneur in China. It illustrates the ways in which the World Wildlife Fund for Nature is active in promoting integrated river basin management in the Yangtze River basin and how the efforts at basin level are matched with the advice of the China Council for International Cooperation on Environment and Development task force on integrated river basin management to the national government of China. This article demonstrates that the World Wildlife Fund for Nature uses various strategies of different types to support a transition process towards integrated river basin management. Successful deployment of these strategies for change in environmental policy requires special skills, actions, and attitudes on the part of the policy entrepreneur, especially in China, where the government has a dominant role regarding water management and the position of policy entrepeneurs is delicate.

  19. PENATAAN RUANG LAUT BERDASARKAN INTEGRATED COASTAL MANAGEMENT

    Directory of Open Access Journals (Sweden)

    Dina Sunyowati

    2008-10-01

    Full Text Available The planning of coastal spatial arrangement must be put in the valid spatial planning system. Law Number 26 of 2007 on Spatial Planning and it is in fact related with land spatial planning, although that ocean and air spatial management will be arranged in separate law. The legal for coastal zone management is determined by using the principles of integrated coastal management by focusing on area or zone authority system. The integrated of coastal zones management regulations should be followed by the planning of coastal spatial arrange­ment. Therefore, certain synchronization at coastal zones governance is very important issue since by integrating and coordinating other related regulations and therefore conflict of norm can be minimized in the spatial planning coastal zone.

  20. Integrated therapy safety management system

    Science.gov (United States)

    Podtschaske, Beatrice; Fuchs, Daniela; Friesdorf, Wolfgang

    2013-01-01

    Aims The aim is to demonstrate the benefit of the medico-ergonomic approach for the redesign of clinical work systems. Based on the six layer model, a concept for an ‘integrated therapy safety management’ is drafted. This concept could serve as a basis to improve resilience. Methods The concept is developed through a concept-based approach. The state of the art of safety and complexity research in human factors and ergonomics forms the basis. The findings are synthesized to a concept for ‘integrated therapy safety management’. The concept is applied by way of example for the ‘medication process’ to demonstrate its practical implementation. Results The ‘integrated therapy safety management’ is drafted in accordance with the six layer model. This model supports a detailed description of specific work tasks, the corresponding responsibilities and related workflows at different layers by using the concept of ‘bridge managers’. ‘Bridge managers’ anticipate potential errors and monitor the controlled system continuously. If disruptions or disturbances occur, they respond with corrective actions which ensure that no harm results and they initiate preventive measures for future procedures. The concept demonstrates that in a complex work system, the human factor is the key element and final authority to cope with the residual complexity. The expertise of the ‘bridge managers’ and the recursive hierarchical structure results in highly adaptive clinical work systems and increases their resilience. Conclusions The medico-ergonomic approach is a highly promising way of coping with two complexities. It offers a systematic framework for comprehensive analyses of clinical work systems and promotes interdisciplinary collaboration. PMID:24007448

  1. Project management plan : Dallas Integrated Corridor Management (ICM) demonstration project.

    Science.gov (United States)

    2010-12-01

    The Dallas Integrated Corridor Management System Demonstration Project is a multi-agency, de-centralized operation which will utilize a set of regional systems to integrate the operations of the corridor. The purpose of the Dallas ICM System is to im...

  2. Knowledge and information management for integrated water resource management

    Science.gov (United States)

    Watershed information systems that integrate data and analytical tools are critical enabling technologies to support Integrated Water Resource Management (IWRM) by converting data into information, and information into knowledge. Many factors bring people to the table to participate in an IWRM fra...

  3. Generalized correlation integral vectors: A distance concept for chaotic dynamical systems

    Energy Technology Data Exchange (ETDEWEB)

    Haario, Heikki, E-mail: heikki.haario@lut.fi [School of Engineering Science, Lappeenranta University of Technology, Lappeenranta (Finland); Kalachev, Leonid, E-mail: KalachevL@mso.umt.edu [Department of Mathematical Sciences, University of Montana, Missoula, Montana 59812-0864 (United States); Hakkarainen, Janne [Earth Observation Unit, Finnish Meteorological Institute, Helsinki (Finland)

    2015-06-15

    Several concepts of fractal dimension have been developed to characterise properties of attractors of chaotic dynamical systems. Numerical approximations of them must be calculated by finite samples of simulated trajectories. In principle, the quantities should not depend on the choice of the trajectory, as long as it provides properly distributed samples of the underlying attractor. In practice, however, the trajectories are sensitive with respect to varying initial values, small changes of the model parameters, to the choice of a solver, numeric tolerances, etc. The purpose of this paper is to present a statistically sound approach to quantify this variability. We modify the concept of correlation integral to produce a vector that summarises the variability at all selected scales. The distribution of this stochastic vector can be estimated, and it provides a statistical distance concept between trajectories. Here, we demonstrate the use of the distance for the purpose of estimating model parameters of a chaotic dynamic model. The methodology is illustrated using computational examples for the Lorenz 63 and Lorenz 95 systems, together with a framework for Markov chain Monte Carlo sampling to produce posterior distributions of model parameters.

  4. European integration and cooperation, basic vectors of European space of freedom, security and justice

    Directory of Open Access Journals (Sweden)

    Ion Balaceanu

    2013-03-01

    Full Text Available European integration and cooperation, basic vectors of European space of freedom, security and justiceAbstract: The European countries joining to the Schengen area had the effect elimination of internal border controls between Schengen member countries, that use permenent provisions of the Schengen acquis, being a single external border where operational checks are carried out according to a set of clear rules on immigration, visas, the asylum, as well as some decisions concerning police cooperation, judicial or customs. This means that the border crossing can be made at any time through many places, and citizens of member countries who are traveling in the Schengen area must present a valid ID. Overcoming internal border can be equated with a journey through the country.

  5. Integrated water and waste management

    DEFF Research Database (Denmark)

    Harremoës, P.

    1997-01-01

    The paper discusses concepts and developments within water quantity, water quality, integrated environmental assessment and wastewater treatment. The historical and the global perspectives are used in the discussion of the role of engineers in today's society. Sustainabilty and ethics are taken...... into the analysis. There is a need for re-evaluation of the resource, society and environment scenarios with a view to the totality of the system and with proper analysis of the flow of water and matter through society. Among the tools are input-output analysis and cradle to grave analysis, in combination...... with compilation of identified sets of values with respect to sustainable use of resources and ultimate fate of the environment and quality of life. The role of the engineer is to make available to society as many technical options as possible - and to put these options into the proper perspective in relation...

  6. Y-12 Integrated Materials Management System

    Energy Technology Data Exchange (ETDEWEB)

    Alspaugh, D. H.; Hickerson, T. W.

    2002-06-03

    The Integrated Materials Management System, when fully implemented, will provide the Y-12 National Security Complex with advanced inventory information and analysis capabilities and enable effective assessment, forecasting and management of nuclear materials, critical non-nuclear materials, and certified supplies. These capabilities will facilitate future Y-12 stockpile management work, enhance interfaces to existing National Nuclear Security Administration (NNSA) corporate-level information systems, and enable interfaces to planned NNSA systems. In the current national nuclear defense environment where, for example, weapons testing is not permitted, material managers need better, faster, more complete information about material properties and characteristics. They now must manage non-special nuclear material at the same high-level they have managed SNM, and information capabilities about both must be improved. The full automation and integration of business activities related to nuclear and non-nuclear materials that will be put into effect by the Integrated Materials Management System (IMMS) will significantly improve and streamline the process of providing vital information to Y-12 and NNSA managers. This overview looks at the kinds of information improvements targeted by the IMMS project, related issues, the proposed information architecture, and the progress to date in implementing the system.

  7. Integrated solid waste management in megacities

    Directory of Open Access Journals (Sweden)

    M.A. Abdoli

    2016-05-01

    Full Text Available Rapid urbanization and industrialization, population growth and economic growth in developing countries make management of municipal solid waste more complex comparing with developed countries. Furthermore, the conventional municipal solid waste management approach often is reductionists, not tailored to handle complexity. Therefore, the need to a comprehensive and multi-disciplinary approach regarding the municipal solid waste management problems is increasing. The concept of integrated solid waste management is accepted for this aim all over the world. This paper analyzes the current situation as well as opportunities and challenges regarding municipal solid waste management in Isfahan according to the integrated solid waste management framework in six aspects: environmental, political/legal, institutional, socio-cultural, financial/economic, technical and performance aspects. Based on the results obtained in this analysis, the main suggestions for future integrated solid waste management of Isfahan are as i promoting financial sustainability by taking the solid waste fee and reducing the expenses through the promoting source collection of recyclable materials, ii improving compost quality and also marketing the compost products simultaneously, iii promoting the private sector involvements throughout the municipal solid waste management system.

  8. Integrating incident investigation into the management system

    International Nuclear Information System (INIS)

    Peterson, E.E.

    1992-01-01

    In the last 10 yr, the size and frequency of incidents affecting the communities and environment surrounding chemical processing facilities has increased. The chemical process industry, which has always concerned itself with the safety of its facilities, has responded by committing to stricter standards of operation and management. A critical element of these management practices is the use of a structured incident investigation program. Many facilities have implemented and disciplined themselves to perform good investigation of incidents. However, most of these facilities maintain incident investigation as part of their safety management programs. This allows the process to be disconnected from the management system that deals with the day-to-day business of the facility. The first step of integration is understanding the objectives and functions of the management system into which the integration is to occur. To begin, a common definition of management is needed. Management, for the purposes of this discussion, is defined as the system of activities used to control, coordinate, and improve the flow of work within a facility or organization. This definition refers to several concepts that need further development in order to understand how incident investigation can be integrated into a management system, including (a) flow of work, (b) control, and (c) improvement. Application can be made to the nuclear industry

  9. Y-12 Integrated Materials Management System

    International Nuclear Information System (INIS)

    Alspaugh, D. H.; Hickerson, T. W.

    2002-01-01

    The Integrated Materials Management System, when fully implemented, will provide the Y-12 National Security Complex with advanced inventory information and analysis capabilities and enable effective assessment, forecasting and management of nuclear materials, critical non-nuclear materials, and certified supplies. These capabilities will facilitate future Y-12 stockpile management work, enhance interfaces to existing National Nuclear Security Administration (NNSA) corporate-level information systems, and enable interfaces to planned NNSA systems. In the current national nuclear defense environment where, for example, weapons testing is not permitted, material managers need better, faster, more complete information about material properties and characteristics. They now must manage non-special nuclear material at the same high-level they have managed SNM, and information capabilities about both must be improved. The full automation and integration of business activities related to nuclear and non-nuclear materials that will be put into effect by the Integrated Materials Management System (IMMS) will significantly improve and streamline the process of providing vital information to Y-12 and NNSA managers. This overview looks at the kinds of information improvements targeted by the IMMS project, related issues, the proposed information architecture, and the progress to date in implementing the system

  10. Integrated management in calcareous soils

    International Nuclear Information System (INIS)

    Castilla, Luis A; Salive, A

    2001-01-01

    Rice growing is developed in different kinds of soils, and some of the have high bases saturation, especially calcium and magnesium, as well as medium to high carbonate contents. This causes negative effects in the development and growth of the rice plant. As a consequence, several researching actions have been under-taken, and they are aimed at becoming this problem in economically manageable. Among the strategies we have, some of them are as follows: evaluating rice varieties presenting tolerance to these soils; using inorganic fertilizers looking for a response to elements, sources, dose and application times; evaluating organic fertilizers, mainly the green ones; using amendments, and physical soil management. According to the results, we have the fertilization response with major and minor elements and with the statistical differences at a 0.05% level. A response was found with elements such as zinc, copper, boron, iron, phosphorus and potassium. However, the efficiency of these elements depends on the addition of amendments as sulfur, the use of green fertilizers and farming systems that eliminate the superficial compaction of these soils, besides the use of varieties which are more tolerant to alkalinity, just like Fedearroz-50

  11. An Effective NoSQL-Based Vector Map Tile Management Approach

    Directory of Open Access Journals (Sweden)

    Lin Wan

    2016-11-01

    Full Text Available Within a digital map service environment, the rapid growth of Spatial Big-Data is driving new requirements for effective mechanisms for massive online vector map tile processing. The emergence of Not Only SQL (NoSQL databases has resulted in a new data storage and management model for scalable spatial data deployments and fast tracking. They better suit the scenario of high-volume, low-latency network map services than traditional standalone high-performance computer (HPC or relational databases. In this paper, we propose a flexible storage framework that provides feasible methods for tiled map data parallel clipping and retrieval operations within a distributed NoSQL database environment. We illustrate the parallel vector tile generation and querying algorithms with the MapReduce programming model. Three different processing approaches, including local caching, distributed file storage, and the NoSQL-based method, are compared by analyzing the concurrent load and calculation time. An online geological vector tile map service prototype was developed to embed our processing framework in the China Geological Survey Information Grid. Experimental results show that our NoSQL-based parallel tile management framework can support applications that process huge volumes of vector tile data and improve performance of the tiled map service.

  12. Renewed mer model of integral management

    Directory of Open Access Journals (Sweden)

    Janko Belak

    2015-12-01

    Full Text Available Background: The research work on entrepreneurship, enterprise's policy and management, which started in 1992, successfully continued in the following years. Between 1992 and 2011, more than 400 academics and other researchers have participated in research work (MER research program whose main orientation has been the creation of their own model of integral management. Results: In past years, academics (researchers and authors of published papers from Austria, Belgium, Bosnia and Herzegovina, Bulgaria, Byelorussia, Canada, the Czech Republic, Croatia, Estonia, France, Germany, Hungary, Italy, Poland, Romania, Russia, the Slovak Republic, Slovenia, Switzerland, Ukraine, and the US have cooperated in MER programs, coming from more than fifty institutions. Thus, scientific doctrines of different universities influenced the development of the MER model which is based on both horizontal and vertical integration of the enterprises' governance and management processes, instruments and institutions into a consistently operating unit. Conclusions: The presented MER model is based on the multi-layer integration of governance and management with an enterprise and its environment, considering the fundamental desires for the enterprises' existence and, thus, their quantitative as well as qualitative changes. The process, instrumental, and institutional integrity of the governance and management is also the initial condition for the implementation of all other integration factors.

  13. Power management techniques for integrated circuit design

    CERN Document Server

    Chen, Ke-Horng

    2016-01-01

    This book begins with the premise that energy demands are directing scientists towards ever-greener methods of power management, so highly integrated power control ICs (integrated chip/circuit) are increasingly in demand for further reducing power consumption. * A timely and comprehensive reference guide for IC designers dealing with the increasingly widespread demand for integrated low power management * Includes new topics such as LED lighting, fast transient response, DVS-tracking and design with advanced technology nodes * Leading author (Chen) is an active and renowned contributor to the power management IC design field, and has extensive industry experience * Accompanying website includes presentation files with book illustrations, lecture notes, simulation circuits, solution manuals, instructors manuals, and program downloads.

  14. Murine leukemia virus vector integration favors promoter regions and regional hot spots in a human T-cell line

    International Nuclear Information System (INIS)

    Tsukahara, Tomonori; Agawa, Hideyuki; Matsumoto, Sayori; Matsuda, Mizuho; Ueno, Shuichi; Yamashita, Yuki; Yamada, Koichiro; Tanaka, Nobuyuki; Kojima, Katsuhiko; Takeshita, Toshikazu

    2006-01-01

    Genomic analysis of integration will be important in evaluating the safety of human gene therapy with retroviral vectors. Here, we investigated MLV vector integration sites in human T-cells, since they are amenable to gene transfer studies, and have been used therapeutically in clinical trials. We mapped 340 MLV vector integration sites in the infected human T-cell clones we established. The data showed that MLV preferred integration near the transcription start sites (±5 kb), near CpG islands (±1 kb), and within the first intron of RefSeq genes. We also identified MLV integration hot spots that contained three or more integrations within a 100 kb region. RT-PCR revealed that mRNA-levels of T-cell clones that contained MLV integrations near transcription start sites or introns were dysregulated compared to the uninfected cells. These studies help define the profile of MLV integration in T-cells and the risks associated with MLV-based gene therapy

  15. CANDU plant life management - An integrated approach

    International Nuclear Information System (INIS)

    Hopkins, J.R.

    1998-01-01

    An integrated approach to plant life management has been developed for CANDU reactors. Strategies, methods, and procedures have been developed for assessment of critical systems structures and components and for implementing a reliability centred maintenance program. A Technology Watch program is being implemented to eliminate 'surprises'. Specific work has been identified for 1998. AECL is working on the integrated program with CANDU owners and seeks participation from other CANDU owners

  16. Current procedures of the integrated urban vector-mosquito control as an example in Cotonou (Benin, West Africa) and Wrocław area (Poland).

    Science.gov (United States)

    Rydzanicz, Katarzyna; Lonc, Elzbieta; Becker, Norbert

    2009-01-01

    Current strategy of Integrated Vector Management (IVM) comprises the general approach of environmentally friendly control measures. With regard to mosquitoes it includes first of all application of microbial insecticides based on Bacillus thuringiensis israelensis (Bti) and B. sphaericus (Bs) delta-endotoxins as well as the reduction of breeding habitats and natural enemy augmentation. It can be achieved thorough implementation of the interdisciplinary program, i. e., understanding of mosquito vector ecology, the appropriate vector-diseases (e. g., malariometric) measurements and training of local personnel responsible for mosquito abatement activities, as well as community involvement. Biocontrol methods as an alternative to chemical insecticides result from the sustainability development concept, growing awareness of environmental pollution and the development of insecticide-resistant strains of vector-mosquito populations in many parts of the world. Although sustainable trends are usually considered in terms of the monetary and training resources within countries, environmental concerns are actually more limiting factors for the duration of an otherwise successful vector control effort. In order to meet these new needs, increasing efforts have been made in search of and application of natural enemies, such as parasites, bacterial pathogens and predators which may control populations of insect vectors. The biological control agent based on the bacterial toxins Bti and Bs has been used in the Wrocław's University and Municipal Mosquito Control Programs since 1998. In West-Africa biocontrol appears to be an effective and safe tool to combat malaria in addition to bed-nets, residual indoor spraying and appropriate diagnosis and treatment of malaria parasites which are the major tools in the WHO Roll Back Malaria Program. IVM studies carried out 2005-2008 in Cotonou (Benin) as well those in Wrocław Irrigated Fields during the last years include the following major

  17. Integration of Standardized Management Systems: A Dilemma?

    Directory of Open Access Journals (Sweden)

    Manuel Ferreira Rebelo

    2015-06-01

    Full Text Available The growing proliferation of management systems standards (MSSs, and their individualized implementation, is a real problem faced by organizations. On the other hand, MSSs are aimed at improving efficiency and effectiveness of organizational responses in order to satisfy the requirements, needs and expectations of the stakeholders. Each organization has its own identity and this is an issue that cannot be neglected; hence, two possible approaches can be attended. First, continue with the implementation of individualized management systems (MSs; or, integrate the several MSSs versus related MSs into an integrated management system (IMS. Therefore, in this context, organizations are faced with a dilemma, as a result of the increasing proliferation and diversity of MSSs. This paper takes into account the knowledge gained through a case study conducted in the context of a Portuguese company and unveils some of the advantages and disadvantages of integration. A methodology is also proposed and presented to support organizations in developing and structuring the integration process of their individualized MSs, and consequently minimize problems that are generators of inefficiencies, value destruction and loss of competitiveness. The obtained results provide relevant information that can support Top Management decision in solving that dilemma and consequently promote a successful integration, including a better control of business risks associated to MSSs requirements and enhancing sustainable performance, considering the context in which organizations operate.

  18. Development and implementation of integrated management system

    International Nuclear Information System (INIS)

    Tomov, E.; Nenkova, B.

    2013-01-01

    Risk Engineering Ltd is a private Bulgarian company in the field of scientific technical consultancy and engineering services, established in 1990. The aim of this report is to present the experience of Risk Engineering Ltd. in the development, implementation and operation of an integrated management system. The process of implementation of the system was completed at the end of 2011. In January 2012, the Risk Engineering Integrated Management System was certified by Lloyd's Register for compliance with standards ISO 9001:2008, ISO 140001:2004 and BS OHSAS 18001:2007

  19. Integrated economic management. Principal aspects and future

    International Nuclear Information System (INIS)

    2004-01-01

    Now that five years have passed (1999-2003) since the Owner Companies decided to merge the Asco and Vandellos-II nuclear power plants, we believe that, for Integrated Management through a single AIE, it is timely and advisable to describe the key issues of the process implemented to optimize economic results, always in accordance with the Policies of Nuclear Safety, Quality and Environment, Prevention, Human Factors and Availability, and we emphasize the following as essential elements: The Corporate Model; strategic/Operating Plans; integrated Economic Management Model SIE; Rationalization of the organizational structure, Continuous Training; Analysis of Processes and Procedures. (Author)

  20. Incorporating double copies of a chromatin insulator into lentiviral vectors results in less viral integrants

    DEFF Research Database (Denmark)

    Nielsen, Troels T; Jakobsson, Johan; Rosenqvist, Nina

    2009-01-01

    BACKGROUND: Lentiviral vectors hold great promise as gene transfer vectors in gene therapeutic settings. However, problems related to the risk of insertional mutagenesis, transgene silencing and positional effects have stalled the use of such vectors in the clinic. Chromatin insulators are boundary...

  1. Economic Exposure and Integrated Risk Management

    OpenAIRE

    Miller, Kent D.

    1994-01-01

    Most corporate risk management research focuses on particular risk exposures to the exclusion of other interrelated exposures. By contrast, this study models corporate risk exposures using a multivariate approach integrating the distinct exposures of interest to finance and strategy researchers. The paper addresses the implications of multivariate modeling for corporate risk management, some key methodological issues arising in empirical estimation of corporate economic exposrues, and direc...

  2. Integrated Management System - Scope, Possibilities And Methodology

    Science.gov (United States)

    Čekanová, Katarína

    2015-06-01

    Organizations are becoming more aware of the importance of integrated management systems (IMS). Interest in this subject indicates that IMS are seen as "management systems of the future". Based on this, the aim of this articles characterizes the possibility of building IMS through the identification of common elements and specific requirements in accordance with the ISO 9001, ISO 14001 and OHSAS 18001 professional references. Part of the article is the methodology of building IMS in the organization.

  3. Application of Numerical Integration and Data Fusion in Unit Vector Method

    Science.gov (United States)

    Zhang, J.

    2012-01-01

    The Unit Vector Method (UVM) is a series of orbit determination methods which are designed by Purple Mountain Observatory (PMO) and have been applied extensively. It gets the conditional equations for different kinds of data by projecting the basic equation to different unit vectors, and it suits for weighted process for different kinds of data. The high-precision data can play a major role in orbit determination, and accuracy of orbit determination is improved obviously. The improved UVM (PUVM2) promoted the UVM from initial orbit determination to orbit improvement, and unified the initial orbit determination and orbit improvement dynamically. The precision and efficiency are improved further. In this thesis, further research work has been done based on the UVM: Firstly, for the improvement of methods and techniques for observation, the types and decision of the observational data are improved substantially, it is also asked to improve the decision of orbit determination. The analytical perturbation can not meet the requirement. So, the numerical integration for calculating the perturbation has been introduced into the UVM. The accuracy of dynamical model suits for the accuracy of the real data, and the condition equations of UVM are modified accordingly. The accuracy of orbit determination is improved further. Secondly, data fusion method has been introduced into the UVM. The convergence mechanism and the defect of weighted strategy have been made clear in original UVM. The problem has been solved in this method, the calculation of approximate state transition matrix is simplified and the weighted strategy has been improved for the data with different dimension and different precision. Results of orbit determination of simulation and real data show that the work of this thesis is effective: (1) After the numerical integration has been introduced into the UVM, the accuracy of orbit determination is improved obviously, and it suits for the high-accuracy data of

  4. Toward integrated design of waste management technologies

    International Nuclear Information System (INIS)

    Carnes, S.A.; Wolfe, A.K.

    1994-01-01

    Implementation of waste management technologies has been hindered by the intervention of diverse interests. Relying on a perceived history of inadequate and improper management, operations, and technological design, critics have stymied the implementation of scientifically and governmentally approved technologies and facilities, leading to a critical shortage of hazardous, mixed, and radioactive waste management capacity. The research and development (R ampersand D) required to identify technologies that are simultaneously (1) scientifically valid, (2) economically sound, and (3) publicly acceptable must necessarily address, in an integrated and interdisciplinary manner, these three criteria and how best to achieve the integration of stakeholders early in the technology implementation process (i.e., R ampersand D, demonstration, and commercialization). The goal of this paper is to initiate an identification of factors likely to render radioactive and hazardous waste management technologies publicly acceptable and to provide guidance on how technological R ampersand D might be revised to enhance the acceptability of alternative waste management technologies. Principal among these factors are the equitable distribution of costs, risks, and benefits of waste management policies and technologies, the equitable distribution of authority for making waste management policy and selecting technologies for implementation, and the equitable distribution of responsibility for resolving waste management problems. Stakeholder participation in assessing the likely distribution of these factors and mitigative mechanisms to enhance their equitable distribution, together with stakeholder participation in policy and technology R ampersand D, as informed by stakeholder assessments, should enhance the identification of acceptable policies and technologies

  5. A Novel Integrated Algorithm for Wind Vector Retrieval from Conically Scanning Scatterometers

    Directory of Open Access Journals (Sweden)

    Xuetong Xie

    2013-11-01

    Full Text Available Due to the lower efficiency and the larger wind direction error of traditional algorithms, a novel integrated wind retrieval algorithm is proposed for conically scanning scatterometers. The proposed algorithm has the dual advantages of less computational cost and higher wind direction retrieval accuracy by integrating the wind speed standard deviation (WSSD algorithm and the wind direction interval retrieval (DIR algorithm. It adopts wind speed standard deviation as a criterion for searching possible wind vector solutions and retrieving a potential wind direction interval based on the change rate of the wind speed standard deviation. Moreover, a modified three-step ambiguity removal method is designed to let more wind directions be selected in the process of nudging and filtering. The performance of the new algorithm is illustrated by retrieval experiments using 300 orbits of SeaWinds/QuikSCAT L2A data (backscatter coefficients at 25 km resolution and co-located buoy data. Experimental results indicate that the new algorithm can evidently enhance the wind direction retrieval accuracy, especially in the nadir region. In comparison with the SeaWinds L2B Version 2 25 km selected wind product (retrieved wind fields, an improvement of 5.1° in wind direction retrieval can be made by the new algorithm for that region.

  6. Integrated ageing management of Atucha NPP

    International Nuclear Information System (INIS)

    Ranalli, Juan M.; Marchena, Martin H.; Zorrilla, Jorge R.; Antonaccio, Elvio E.; Brenna, Pablo; Yllanez, Daniela; Cruz, Gerardo Vera de la; Luraschi, Carlos; Sabransky, Mario

    2013-01-01

    Atucha NPP is a two PHWR unit site located in Lima, Province of Buenos Aires, 120 km north of Buenos Aires, Argentina. Until recent, the site was split in Atucha I NPP, a 350 MW pressure vessel heavy water reactor in operation since 1974; and Atucha II, a similar design reactor, twice as big as Atucha I finishing a delayed construction. With the start-up of Atucha II and aiming to integrate the management of the plants, the Utility (Nucleolectrica Argentina Sociedad Anonima - NASA) has reorganized its operation units. Within this reorganization, an Ageing Management Department has been created to cope with all ageing issues of both Atucha I and II units. The Atomic Energy Commission of Argentina (Comision Nacional de Energia Atomica - CNEA) is a state-owned R and D organization that; among other functions such as designing and building research reactors, developing uranium mining and supplying radioisotopes to the medical market; is in charge of providing support and technological update to all Argentinean NPPs. The Ageing Management Department of Atucha NPP and the Ageing Management Division of CNEA has formed a joint working group in order to set up an Integrated Ageing Management Program for Atucha NPP following IAEA guidelines. In the present work a summary of the activities, documental structure and first outputs of the Integrated Ageing Management Program of Atucha NPP is presented. (author)

  7. Integrated Ageing Management of Atucha NPP

    International Nuclear Information System (INIS)

    Ranalli, J.M.; Marchena, M.H.; Zorrilla, J.R.; Sabransky, M.

    2012-01-01

    Atucha NPP is a two PHWR unit site located in Lima, Province of Buenos Aires, 120 km north of Buenos Aires, Argentina. Until recent, the site was split in Atucha I NPP, a 350 MW pressure vessel heavy water reactor in operation since 1974; and Atucha II, a similar design reactor twice as big as Atucha I finishing a delayed construction . With the start-up of Atucha II and aiming to integrate the management of the plants, the Utility (Nucleolectrica Argentina Sociedad Anonima - NASA) has reorganized its operation units. Within this reorganization, an Ageing Management Department has been created to cope with all ageing issues of both Atucha I and II units. The Atomic Energy Commission of Argentina (Comision Nacional de Energia Atomica - CNEA) is a state-owned R and D organization that; among other functions such as designing and building research reactors, developing uranium mining and supplying radioisotopes to the medical market; is in charge of providing support and technological update to all Argentinean NPPs. The Ageing Management Department of Atucha NPP and the Ageing Management Division of CNEA has formed a joint working group in order to set up an Integrated Ageing Management Program for Atucha NPP following IAEA guidelines. In the present work a summary of the activities, documental structure and first outputs of the Integrated Ageing Management Program of Atucha NPP is presented. (author)

  8. Integrated ageing management of Atucha NPP

    Energy Technology Data Exchange (ETDEWEB)

    Ranalli, Juan M.; Marchena, Martin H.; Zorrilla, Jorge R.; Antonaccio, Elvio E.; Brenna, Pablo; Yllanez, Daniela; Cruz, Gerardo Vera de la; Luraschi, Carlos, E-mail: ranalli@cnea.gov.ar [Gerencia Coordinacion Proyectos CNEA-NASA, Comision Nacional de Energia Atomica, Buenos Aires (Argentina); Sabransky, Mario, E-mail: msabransky@na-sa.com.ar [Departamento Gestion de Envejecimiento, Central Nuclear Atucha I-II Nucleoelectrica Argentina S.A., Provincia de Buenos Aires (Argentina)

    2013-07-01

    Atucha NPP is a two PHWR unit site located in Lima, Province of Buenos Aires, 120 km north of Buenos Aires, Argentina. Until recent, the site was split in Atucha I NPP, a 350 MW pressure vessel heavy water reactor in operation since 1974; and Atucha II, a similar design reactor, twice as big as Atucha I finishing a delayed construction. With the start-up of Atucha II and aiming to integrate the management of the plants, the Utility (Nucleolectrica Argentina Sociedad Anonima - NASA) has reorganized its operation units. Within this reorganization, an Ageing Management Department has been created to cope with all ageing issues of both Atucha I and II units. The Atomic Energy Commission of Argentina (Comision Nacional de Energia Atomica - CNEA) is a state-owned R and D organization that; among other functions such as designing and building research reactors, developing uranium mining and supplying radioisotopes to the medical market; is in charge of providing support and technological update to all Argentinean NPPs. The Ageing Management Department of Atucha NPP and the Ageing Management Division of CNEA has formed a joint working group in order to set up an Integrated Ageing Management Program for Atucha NPP following IAEA guidelines. In the present work a summary of the activities, documental structure and first outputs of the Integrated Ageing Management Program of Atucha NPP is presented. (author)

  9. Integrating cost management and work management concepts for operations

    International Nuclear Information System (INIS)

    Vanditmars, C.

    1995-01-01

    Development of B C Gas Utility Limited's integrated work and cost management system was described, with emphasis on cost management without reliance on the financial systems, and standard costing and operational side benefits. The objectives of the system were identified as dynamic monitoring and control, and local empowerment. The concept underlying the two systems was explained in detail. In the case of the work management system the ability to manage all work in operations areas was stressed, along with its universal availability. Other benefits expected included improved resource utilization, improved productivity, better control of cost, improved revenue generation, superior customer service, a simplified financial system, and improved employee motivation through empowerment

  10. Plant life management. Progress for structural integrity

    International Nuclear Information System (INIS)

    Solin, J.

    2003-03-01

    A joint project cluster of industry, VTT and other R and D suppliers is dealing with managing of lifetime of critical structures and components in energy and process industry. The research topics include systematic component lifetime management, data management, integrity and lifetime of pressure bearing components, non-destructive inspection, interactions of coolant and materials, environmentally assisted cracking and ageing of reactor internals. This Symposium is a compilation of selected papers describing an intermediate status of the projects after three years of research and development. (orig.)

  11. Integrated Pest Management Research Symposium: The Proceedings

    Science.gov (United States)

    Susan J. Branham; Robert C. Thatcher; [Editors

    1985-01-01

    Thirty-seven papers are presented that summarize the findings from research and development work conducted as a part of the Integrated Pest Management RD&A Program for Bark Beetles of Southern Pines during the 5-year period 1980-85. Presentations cover the areas of sampling and impact assessment, bark beetle biology and ecology, host susceptibility, host/pest...

  12. Integrated Management of Structural Pests in Schools.

    Science.gov (United States)

    Illinois State Dept. of Public Health, Springfield.

    The state of Illinois is encouraging schools to better inspect and evaluate the causes of their pest infestation problems through use of the Integrated Pest Management (IPM) guidelines developed by the Illinois Department of Public Health. This guide reviews the philosophy and organization of an IPM program for structural pests in schools,…

  13. Integrated System Health Management Development Toolkit

    Science.gov (United States)

    Figueroa, Jorge; Smith, Harvey; Morris, Jon

    2009-01-01

    This software toolkit is designed to model complex systems for the implementation of embedded Integrated System Health Management (ISHM) capability, which focuses on determining the condition (health) of every element in a complex system (detect anomalies, diagnose causes, and predict future anomalies), and to provide data, information, and knowledge (DIaK) to control systems for safe and effective operation.

  14. Implementing Integrated River Basin Management in China

    NARCIS (Netherlands)

    Boekhorst, D.G.J. te; Smits, A.J.M.; Yu, X.; Lifeng, L.; Lei, G.; Zhang, C.

    2010-01-01

    This paper examines the role of the World Wildlife Fund for Nature China as policy entrepreneur in China. It illustrates the ways in which the World Wildlife Fund for Nature is active in promoting integrated river basin management in the Yangtze River basin and how the efforts at basin level are

  15. Factors influencing implementation of integrated management of ...

    African Journals Online (AJOL)

    Background: Save the Children Tanzania has been supporting several projects in Lindi Region including implementation of health facility based Integrated Management of Childhood Illness (IMCI) services in Kilwa, Ruangwa and Lindi rural districts. The objective of this study was to assess the IMCI services in a sample of ...

  16. Integrated environment, safety, and health management system description

    International Nuclear Information System (INIS)

    Zoghbi, J. G.

    2000-01-01

    The Integrated Environment, Safety, and Health Management System Description that is presented in this document describes the approach and management systems used to address integrated safety management within the Richland Environmental Restoration Project

  17. Risk Informed Structural Systems Integrity Management

    DEFF Research Database (Denmark)

    Nielsen, Michael Havbro Faber

    2017-01-01

    The present paper is predominantly a conceptual contribution with an appraisal of major developments in risk informed structural integrity management for offshore installations together with a discussion of their merits and the challenges which still lie ahead. Starting point is taken in a selected...... overview of research and development contributions which have formed the basis for Risk Based Inspection Planning (RBI) as we know it today. Thereafter an outline of the methodical basis for risk informed structural systems integrity management, i.e. the Bayesian decision analysis is provided in summary....... The main focus is here directed on RBI for offshore facilities subject to fatigue damages. New ideas and methodical frameworks in the area of robustness and resilience modeling of structural systems are then introduced, and it is outlined how these may adequately be utilized to enhance Structural Integrity...

  18. Configuration Management Program - a part of Integrated Management System

    International Nuclear Information System (INIS)

    Mancev, Bogomil; Yordanova, Vanja; Nenkova, Boyka

    2014-01-01

    The recently issued International Atomic Energy Agency (IAEA) publications (GS-R-3, GS-G-3.1 and GS-G-3.5) regarding Management Systems for Facilities and Activities define requirements for creation, introduction, evaluation and continuously improvement of the Management System, which unifies the safety, health, environment, security, quality and economic elements. According to GS-R-3 the Integrated Management System is based on defined processes identified in the enterprises: Managing, Basic and Supporting processes. At implementation of their activities, the organizations often apply other standards in their interrelations with suppliers and the parties concerned - ISO 9001:2008, ISO 14001:2004 and OHSAS 18001:2007, regarding quality, environment and occupational health and safety management. The integration of the standards of both series ensure the observance of the common management principles that reflect the best practices of management as leadership, participation of the people, process approach, continuously improvement, systematical approach to the management and approach based on facts used at the making decisions. The main objective of the Integrated Management System introduction is to ensure safety considering the influence of all additional impacts taken together. The Integrated Management System is based on the process approach at implementation of the activities in nuclear power plant. The transition to the process oriented approach require long period of time, during which the distribution of the responsibilities is optimized up to the level that will satisfy the requirements, reach and maintain the stipulated objectives. The Configuration Management (CM) is an integrated management process by means of which conformity between design requirements, physical configuration and the plant documentation is ascertained and maintained during the entire life cycle of the facility. Processes within configuration management are not isolated, but are part of

  19. Integrating the radioactive waste management system into other management systems

    International Nuclear Information System (INIS)

    Silva, Ana Cristina Lourenco da; Nunes Neto, Carlos Antonio

    2007-01-01

    Radioactive waste management is to be included in the Integrated Management System (IMS) which pursues the continuous improvement of the company's quality, occupational safety and health, and environment protection processes. Radioactive waste management is based on the following aspects: optimization of human and material resources for execution of tasks, including the provision of a radiation protection supervisor to watch over the management of radioactive waste; improved documentation (management plan and procedures); optimization of operational levels for waste classification and release; maintenance of generation records and history through a database that facilitates traceability of information; implementation of radioactive waste segregation at source (source identification, monitoring and decontamination) activities intended to reduce the amount of radioactive waste; licensing of initial storage site for radioactive waste control and storage; employee awareness training on radioactive waste generation; identification and evaluation of emergency situations and response planning; implementation of preventive maintenance program for safety related items; development and application of new, advanced treatment methodologies or systems. These aspects are inherent in the concepts underlying quality management (establishment of administrative controls and performance indicators), environment protection (establishment of operational levels and controls for release), occupational health and safety (establishment of operational controls for exposure in emergency and routine situations and compliance with strict legal requirements and standards). It is noted that optimizing the addressed aspects of a radioactive waste management system further enhances the efficiency of the Integrated Management System for Quality, Environment, and Occupational Safety and Health. (author)

  20. Ontology modeling in physical asset integrity management

    CERN Document Server

    Yacout, Soumaya

    2015-01-01

    This book presents cutting-edge applications of, and up-to-date research on, ontology engineering techniques in the physical asset integrity domain. Though a survey of state-of-the-art theory and methods on ontology engineering, the authors emphasize essential topics including data integration modeling, knowledge representation, and semantic interpretation. The book also reflects novel topics dealing with the advanced problems of physical asset integrity applications such as heterogeneity, data inconsistency, and interoperability existing in design and utilization. With a distinctive focus on applications relevant in heavy industry, Ontology Modeling in Physical Asset Integrity Management is ideal for practicing industrial and mechanical engineers working in the field, as well as researchers and graduate concerned with ontology engineering in physical systems life cycles. This book also: Introduces practicing engineers, research scientists, and graduate students to ontology engineering as a modeling techniqu...

  1. Geo-inspired model: Agents vectors naturals inspired by the environmental management (AVNG of water tributaries

    Directory of Open Access Journals (Sweden)

    Edwin Eduardo Millán Rojas

    2018-02-01

    Full Text Available Context: Management to care for the environment and the Earth (geo can be source of inspiration for developing models that allow addressing complexity issues; the objective of this research was to develop an additional aspect of the inspired models. The geoinspired model has two features, the first covering aspects related to environmental management and the behavior of natural resources, and the second has a component of spatial location associated with existing objects on the Earth's surface. Method: The approach developed in the research is descriptive and its main objective is the representation or characterization of a case study within a particular context. Results: The result was the design of a model to emulate the natural behavior of the water tributaries of the Amazon foothills, in order to extend the application of the inspired models and allow the use of elements such as geo-referencing and environmental management. The proposed geoinspired model is called “natural vectors agents inspired in environmental management”. Conclusions: The agents vectors naturals inspired by the environmental are polyform elements that can assume the behavior of environmental entities, which makes it possible to achieve progress in other fields of environmental management (use of soil, climate, flora, fauna, and link environmental issues with the structure of the proposed model.

  2. Integrated Simulation Of Supply Chain Management

    Directory of Open Access Journals (Sweden)

    N.Manikandan

    2013-06-01

    Full Text Available Nowadays, manufacturers face the challenge of reducing manufacturing cycle time, delivery lead time and inventory reduction. Every organization has its own objectives and its own way of decision making processes. Because of the conflictions among the objectives of each organization and non-integrated decision making processes, there has been a need for a new mechanism, which help to resolve those conflictions and to integrate processes. In the early 1990s, management is a process of integrating and utilizing suppliers, manufacturers, warehouses and retailers, so that goods are produced and delivered at the right quantities and at the right time while minimizing costs as well as satisfying customer requirements. Managing the entire supply chain becomes a key factor for the successful business. Organizations now realize that non-integrated manufacturing processes, nonintegrated distribution processes and poor relationships with suppliers and customers are in adequate for their success. The supply chain areas are affected by the organization’s plan. The organization plan’s impact on the supply chain areas cannot be predicted before its execution. Simulation paves way to evaluate the performance of plans before the execution of the plan. This paper describes the effort of developing a simulation model for the supply chain management in an industry. This article discusses the requirement of supply chain simulation modeling.

  3. Classification of polynomial integrable systems of mixed scalar and vector evolution equations: I

    International Nuclear Information System (INIS)

    Tsuchida, Takayuki; Wolf, Thomas

    2005-01-01

    We perform a classification of integrable systems of mixed scalar and vector evolution equations with respect to higher symmetries. We consider polynomial systems that are homogeneous under a suitable weighting of variables. This paper deals with the KdV weighting, the Burgers (or potential KdV or modified KdV) weighting, the Ibragimov-Shabat weighting and two unfamiliar weightings. The case of other weightings will be studied in a subsequent paper. Making an ansatz for undetermined coefficients and using a computer package for solving bilinear algebraic systems, we give the complete lists of second-order systems with a third-order or a fourth-order symmetry and third-order systems with a fifth-order symmetry. For all but a few systems in the lists, we show that the system (or, at least a subsystem of it) admits either a Lax representation or a linearizing transformation. A thorough comparison with recent work of Foursov and Olver is made

  4. Classification of polynomial integrable systems of mixed scalar and vector evolution equations: I

    Energy Technology Data Exchange (ETDEWEB)

    Tsuchida, Takayuki [Department of Physics, Kwansei Gakuin University, 2-1 Gakuen, Sanda 669-1337 (Japan); Wolf, Thomas [Department of Mathematics, Brock University, St Catharines, ON L2S 3A1 (Canada)

    2005-09-02

    We perform a classification of integrable systems of mixed scalar and vector evolution equations with respect to higher symmetries. We consider polynomial systems that are homogeneous under a suitable weighting of variables. This paper deals with the KdV weighting, the Burgers (or potential KdV or modified KdV) weighting, the Ibragimov-Shabat weighting and two unfamiliar weightings. The case of other weightings will be studied in a subsequent paper. Making an ansatz for undetermined coefficients and using a computer package for solving bilinear algebraic systems, we give the complete lists of second-order systems with a third-order or a fourth-order symmetry and third-order systems with a fifth-order symmetry. For all but a few systems in the lists, we show that the system (or, at least a subsystem of it) admits either a Lax representation or a linearizing transformation. A thorough comparison with recent work of Foursov and Olver is made.

  5. Integrated waste and water management system

    Science.gov (United States)

    Murray, R. W.; Sauer, R. L.

    1986-01-01

    The performance requirements of the NASA Space Station have prompted a reexamination of a previously developed integrated waste and water management system that used distillation and catalytic oxydation to purify waste water, and microbial digestion and incineration for waste solids disposal. This system successfully operated continuously for 206 days, for a 4-man equivalent load of urine, feces, wash water, condensate, and trash. Attention is given to synergisms that could be established with other life support systems, in the cases of thermal integration, design commonality, and novel technologies.

  6. Open Source GIS based integrated watershed management

    Science.gov (United States)

    Byrne, J. M.; Lindsay, J.; Berg, A. A.

    2013-12-01

    Optimal land and water management to address future and current resource stresses and allocation challenges requires the development of state-of-the-art geomatics and hydrological modelling tools. Future hydrological modelling tools should be of high resolution, process based with real-time capability to assess changing resource issues critical to short, medium and long-term enviromental management. The objective here is to merge two renowned, well published resource modeling programs to create an source toolbox for integrated land and water management applications. This work will facilitate a much increased efficiency in land and water resource security, management and planning. Following an 'open-source' philosophy, the tools will be computer platform independent with source code freely available, maximizing knowledge transfer and the global value of the proposed research. The envisioned set of water resource management tools will be housed within 'Whitebox Geospatial Analysis Tools'. Whitebox, is an open-source geographical information system (GIS) developed by Dr. John Lindsay at the University of Guelph. The emphasis of the Whitebox project has been to develop a user-friendly interface for advanced spatial analysis in environmental applications. The plugin architecture of the software is ideal for the tight-integration of spatially distributed models and spatial analysis algorithms such as those contained within the GENESYS suite. Open-source development extends knowledge and technology transfer to a broad range of end-users and builds Canadian capability to address complex resource management problems with better tools and expertise for managers in Canada and around the world. GENESYS (Generate Earth Systems Science input) is an innovative, efficient, high-resolution hydro- and agro-meteorological model for complex terrain watersheds developed under the direction of Dr. James Byrne. GENESYS is an outstanding research and applications tool to address

  7. Integrated solid waste management in Japan

    Energy Technology Data Exchange (ETDEWEB)

    1993-10-01

    The Japanese, through a combination of public policy, private market conditions, a geographic necessity, practice integrated municipal solid waste (MSW) management. The approach of MSW management in Japan is as follows: The basic concept of refuse treatment consists of recycling discharged refuse into usable resources, reusing such resources as much as possible, and then treating or disposing of the usable portion into a sanitary condition. Considering the difficulty of procuring land or seaside areas for such purpose as a refuse disposal site, it will be necessary to minimize the volume of refuse collected for treatment or disposal.

  8. Increasing efficiency through integrated energy data management

    International Nuclear Information System (INIS)

    Brack, M.

    2002-01-01

    This article discusses how improved management of energy data can bring about the increase in efficiency that is necessary for an electricity enterprise operating in a liberalised electricity market. The relevant technical and business processes involved for a typical power distribution utility are described. The present situation is reviewed and the various physical, data-logistics and commercial 'domains' involved are examined. Possible solutions for energy data logistics and integrated data management are discussed from the points of view of the operating utility, the power supplier and those responsible for balancing out supply and demand

  9. An introduction to vectors, vector operators and vector analysis

    CERN Document Server

    Joag, Pramod S

    2016-01-01

    Ideal for undergraduate and graduate students of science and engineering, this book covers fundamental concepts of vectors and their applications in a single volume. The first unit deals with basic formulation, both conceptual and theoretical. It discusses applications of algebraic operations, Levi-Civita notation, and curvilinear coordinate systems like spherical polar and parabolic systems and structures, and analytical geometry of curves and surfaces. The second unit delves into the algebra of operators and their types and also explains the equivalence between the algebra of vector operators and the algebra of matrices. Formulation of eigen vectors and eigen values of a linear vector operator are elaborated using vector algebra. The third unit deals with vector analysis, discussing vector valued functions of a scalar variable and functions of vector argument (both scalar valued and vector valued), thus covering both the scalar vector fields and vector integration.

  10. Integrated Systems Health Management for Intelligent Systems

    Science.gov (United States)

    Figueroa, Fernando; Melcher, Kevin

    2011-01-01

    The implementation of an integrated system health management (ISHM) capability is fundamentally linked to the management of data, information, and knowledge (DIaK) with the purposeful objective of determining the health of a system. It is akin to having a team of experts who are all individually and collectively observing and analyzing a complex system, and communicating effectively with each other in order to arrive at an accurate and reliable assessment of its health. In this paper, concepts, procedures, and approaches are presented as a foundation for implementing an intelligent systems ]relevant ISHM capability. The capability stresses integration of DIaK from all elements of a system. Both ground-based (remote) and on-board ISHM capabilities are compared and contrasted. The information presented is the result of many years of research, development, and maturation of technologies, and of prototype implementations in operational systems.

  11. Asset management -- Integrated software optimizes production performance

    International Nuclear Information System (INIS)

    Polczer, S.

    1998-01-01

    Developments in data collection and retrieval systems to allow timely cost analysis, financial reporting and production management are discussed. One of the most important new OLAP (on-line analytical processing) products is Energy Warehouse which gathers field information from various sources, allows advanced searches, and generates reports previously unavailable in other conventional financial accounting systems. Another OLAP-based system, the Canadian Upstream Energy System (CUES), was developed by the Oracle Corporation and the Calgary-based Applied Terravision Systems (ATS) Inc. CUES combines Oracle's universal data server software development tools with ATS's upstream financial, land, geotechnical and production applications. ATS also developed a product called IDPMARS (Integrated Daily Production Management Accounting Reporting System). It interfaces with CUES to link working interests, government royalties, administration, facility charges, lifting costs, transportation tooling, and customers by integrating field data collection systems with financial accounting

  12. Asset management -- Integrated software optimizes production performance

    Energy Technology Data Exchange (ETDEWEB)

    Polczer, S.

    1998-10-01

    Developments in data collection and retrieval systems to allow timely cost analysis, financial reporting and production management are discussed. One of the most important new OLAP (on-line analytical processing) products is Energy Warehouse which gathers field information from various sources, allows advanced searches, and generates reports previously unavailable in other conventional financial accounting systems. Another OLAP-based system, the Canadian Upstream Energy System (CUES), was developed by the Oracle Corporation and the Calgary-based Applied Terravision Systems (ATS) Inc. CUES combines Oracle`s universal data server software development tools with ATS`s upstream financial, land, geotechnical and production applications. ATS also developed a product called IDPMARS (Integrated Daily Production Management Accounting Reporting System). It interfaces with CUES to link working interests, government royalties, administration, facility charges, lifting costs, transportation tooling, and customers by integrating field data collection systems with financial accounting.

  13. Ontario Hydro's integrated air management plan

    International Nuclear Information System (INIS)

    Kalvins, A.K.; Brown, D.; Camacho, F.; Howes, H.; Jantzi, B.; Lin, X.; Lui, P.; Melo, O.T.; Mortimer, W.P.; Reuber, B.

    1992-01-01

    Ontario Hydro is developing an integrated air management plan as a tool for comparing the environmental impacts of fossil-fuel power generation options. The goal is to relate equipment, location, emissions, and impacts and to identify the optimum way to manage the utility's fossil generation system in view of upcoming environmental regulations and public expectations. The eight steps of the plan are briefly described: definition of power generation scenarios (upgrading, conversion to natural gas, non-utility generation, alternative technologies); estimation of emissions for each generation and fuel option studied; identification of impact of air emissions on building materials, agriculture, forests, lakes, and fisheries; modelling of air emissions dispersion; quantification of damage to pollution receptors; quantification of full fuel cycle effects; and comparison of the scenarios. The scenario having the lowest overall environmental impact involved upgrading the existing fossil-fuel system with additional air emissions controls and two integrated gasification combined cycle plants. 9 refs., 3 figs., 3 tabs

  14. Explicit time integration of finite element models on a vectorized, concurrent computer with shared memory

    Science.gov (United States)

    Gilbertsen, Noreen D.; Belytschko, Ted

    1990-01-01

    The implementation of a nonlinear explicit program on a vectorized, concurrent computer with shared memory is described and studied. The conflict between vectorization and concurrency is described and some guidelines are given for optimal block sizes. Several example problems are summarized to illustrate the types of speed-ups which can be achieved by reprogramming as compared to compiler optimization.

  15. Making Technology Ready: Integrated Systems Health Management

    Science.gov (United States)

    Malin, Jane T.; Oliver, Patrick J.

    2007-01-01

    This paper identifies work needed by developers to make integrated system health management (ISHM) technology ready and by programs to make mission infrastructure ready for this technology. This paper examines perceptions of ISHM technologies and experience in legacy programs. Study methods included literature review and interviews with representatives of stakeholder groups. Recommendations address 1) development of ISHM technology, 2) development of ISHM engineering processes and methods, and 3) program organization and infrastructure for ISHM technology evolution, infusion and migration.

  16. Investigation of Integrated Vehicle Health Management Approaches

    Science.gov (United States)

    Paris, Deidre

    2005-01-01

    This report is to present the work that was performed during the summer in the Advance Computing Application office. The NFFP (NASA Faculty Fellow Program) had ten summer faculty members working on IVHM (Integrated Vehicle Health Management) technologies. The objective of this project was two-fold: 1) to become familiar with IVHM concepts and key demonstrated IVHM technologies; and 2) to integrate the research that has been performed by IVHM faculty members into the MASTLAB (Marshall Avionic Software Test Lab). IVHM is a NASA-wide effort to coordinate, integrate and apply advanced software, sensors and design technologies to increase the level of intelligence, autonomy, and health state of future vehicles. IVHM is an important concept because it is consistent with the current plan for NASA to go to the moon, mars, and beyond. In order for NASA to become more involved in deep exploration, avionic systems will need to be highly adaptable and autonomous.

  17. Development of oral CTL vaccine using a CTP-integrated Sabin 1 poliovirus-based vector system.

    Science.gov (United States)

    Han, Seung-Soo; Lee, Jinjoo; Jung, Yideul; Kang, Myeong-Ho; Hong, Jung-Hyub; Cha, Min-Suk; Park, Yu-Jin; Lee, Ezra; Yoon, Cheol-Hee; Bae, Yong-Soo

    2015-09-11

    We developed a CTL vaccine vector by modification of the RPS-Vax system, a mucosal vaccine vector derived from a poliovirus Sabin 1 strain, and generated an oral CTL vaccine against HIV-1. A DNA fragment encoding a cytoplasmic transduction peptide (CTP) was integrated into the RPS-Vax system to generate RPS-CTP, a CTL vaccine vector. An HIV-1 p24 cDNA fragment was introduced into the RPS-CTP vector system and a recombinant poliovirus (rec-PV) named vRPS-CTP/p24 was produced. vRPS-CTP/p24 was genetically stable and efficiently induced Th1 immunity and p24-specific CTLs in immunized poliovirus receptor-transgenic (PVR-Tg) mice. In challenge experiments, PVR-Tg mice that were pre-immunized orally with vRPS-CTP/p24 were resistant to challenge with a lethal dose of p24-expressing recombinant vaccinia virus (rMVA-p24). These results suggested that the RPS-CTP vector system had potential for developing oral CTL vaccines against infectious diseases. Copyright © 2015 Elsevier Ltd. All rights reserved.

  18. Management of area-wide integrated pest management programmes that integrate the sterile insect technique

    International Nuclear Information System (INIS)

    Dyck, V.A.; Vreysen, M.J.B.; Reyes Flores, J.; Regidor Fernandez, E.E.; Teruya, T.; Barnes, B.; Gomez Riera, P.; Lindquist, D.; Loosjes, M.

    2005-01-01

    Effective management of area-wide integrated pest management (AW-IPM) programmes that integrate the sterile insect technique (SIT) is key to success. Programme planning includes collection of baseline data and a feasibility assessment. The optimal management structure is where the programme can be implemented effectively and flexibly, independent of government politics, bureaucracy, and even corruption that impede timely goal achievement. Ideally, programmes include both public and private management, and require strong and steady financial support. Governments and donors are the most common sources of funds, but a mixture of public, community, and private funds is now the trend. Interrupted cash flow severely restrains programme performance. Physical support of programme operations must be reliable, and led by a maintenance professional. It is essential to have full-time, well-paid, and motivated staff led by a programme manger with technical and management experience. Programme failure is usually due to poor management and inadequate public support, and not to poor technology. (author)

  19. A management systems approach to pipeline integrity

    Energy Technology Data Exchange (ETDEWEB)

    Abes, J. [CC Technologies Canada, Calgary, AB (Canada)

    2008-07-01

    A management systems approach to pipeline integrity was discussed in terms of accident causation models, lessons from accidents, and management systems. Accident causation models include the Heinrich domino theory; epidemiological models; event chain models; and system-based models. A review of the Bellingham pipeline accident showed that if the pipeline had not been weakened by external damage, it likely would have been able to withstand the pressure that occurred on the day of the rupture, and the accident would not have happened. It was also determined that there was inadequate inspection of excavation work during the water treatment plant project and consequently, there was a failure to identify and repair the damage done to the pipeline. The presentation also addressed other findings, such as inaccurate evaluation of in-line pipeline inspection data; failure to manage and protect the supervisory control and data acquisition system (SCADA); and ineffective management oversight of construction and activation of products terminal. The Carlsbad pipeline explosion was also presented as another example of an accident. Several violations by El Paso were cited, including failure to ensure that qualified personnel performed internal corrosion control procedures; failure to perform necessary tests for corrosion; and failure to follow procedures for continuing surveillance of its facilities. Last, the presentation provided a definition of management systems and discussed the characteristics and elements of a management system. These elements included policy and leadership commitment; organizational structure and responsibilities; management of resources; communication plan; document and records management; operational controls; management of change; and continual improvement. 1 fig.

  20. Integrating Process Management with Archival Management Systems: Lessons Learned

    Directory of Open Access Journals (Sweden)

    J. Gordon Daines, III

    2009-03-01

    Full Text Available The Integrated Digital Special Collections (INDI system is a prototype of a database-driven, Web application designed to automate and manage archival workflow for large institutions and consortia. This article discusses the how the INDI project enabled the successful implementation of a process to manage large technology projects in the Harold B. Lee Library at Brigham Young University. It highlights how the scope of these technology projects is set and how the major deliverables for each project are defined. The article also talks about how the INDI system followed the process and still failed to be completed. It examines why the process itself is successful and why the INDI project failed. It further underscores the importance of process management in archival management systems.

  1. RISK MANAGEMENT: AN INTEGRATED APPROACH TO RISK MANAGEMENT AND ASSESSMENT

    OpenAIRE

    Szabo Alina

    2012-01-01

    Purpose: The objective of this paper is to offer an overview over risk management cycle by focusing on prioritization and treatment, in order to ensure an integrated approach to risk management and assessment, and establish the ‘top 8-12’ risks report within the organization. The interface with Internal Audit is ensured by the implementation of the scoring method to prioritize risks collected from previous generated risk report. Methodology/approach: Using evidence from other research in ...

  2. Advantages and Limitations of Integrated Management System: the Theoretical Viewpoint

    Directory of Open Access Journals (Sweden)

    Agota Giedrė Raišienė

    2013-08-01

    Full Text Available Purpose. The goal of the paper is to discuss the potential benefits and to highlight the drawbacks of integrated management system for organizations that seek to improve management process.Methodology. Methods of the research were used: analysis of a scientific and special literature that presents the requirements, models and results of integrated management systems studies, and analysis of statistical data to assess actuality of integrated management systems for enterprises in Lithuania.Findings. Summarizing research findings, it should be stated that the implementation of management system integration should be based on provision of social responsibility and holistic approach to the organization. It requires the long-term united efforts of leaders in a strategic hierarchical level and high organizational maturity to ensure the fluency of the running stages of planning management system integration, preparing documentations, implementing and realizing integrated management system. Also it is necessary to purify the conception of integrated management system in organizational context. Theoretical analysis of integrated management systems show, that all of the management systems can not be well integrated in principle. They can only be partly integrated and coordinated. A need to question the level of integration of management systems is very important as in scientific discourse as in practice. It is important to mark, that the number of organizations, that seek to optimize management processes by implementing the integrated management systems is rapidly increasing in Lithuania, too. It shows that benefit associated with integration of management systems is apprehensible in Lithuania. Advantages of integrated management systems can certainly become even stronger if scientists and practicians join their forces in search of methods of organizational management development.Research limitations. The research limitations related to a lack of

  3. Integrated Natural Resource Management in the Highlands of ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    1 janv. 2012 ... Integrated Natural Resource Management in the Highlands of Eastern Africa: ... goal of implementing an integrated approach to natural resource ... and the International Water Management Institute in Addis Ababa, Ethiopia.

  4. Integrated Natural Resource Management in the Highlands of ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2012-01-01

    Jan 1, 2012 ... Book cover Integrated Natural Resource Management in the ... with the common goal of implementing an integrated approach to natural resource ... and the International Water Management Institute in Addis Ababa, Ethiopia.

  5. Concept of operations : Dallas Integrated Corridor Management (ICM) demonstration project.

    Science.gov (United States)

    2010-06-01

    This concept of operations (Con Ops) for the US-75 Integrated Corridor Management (ICM) Program has been developed as part of the US : Department of Transportation Integrated Corridor Management Initiative, which is an innovative research initiative ...

  6. Advantages and Limitations of Integrated Management System: the Theoretical Viewpoint

    Directory of Open Access Journals (Sweden)

    Agota Giedrė Raišienė

    2011-08-01

    Full Text Available Purpose. The goal of the paper is to discuss the potential benefits and to highlight the drawbacks of integrated management system for organizations that seek to improve management process.Methodology. Methods of the research were used: analysis of a scientific and special literature that presents the requirements, models and results of integrated management systems studies, and analysis of statistical data to assess actuality of integrated management systems for enterprises in Lithuania.Findings. Summarizing research findings, it should be stated that the implementation of management system integration should be based on provision of social responsibility and holistic approach to the organization. It requires the long-term united efforts of leaders in a strategic hierarchical level and high organizational maturity to ensure the fluency of the running stages of planning management system integration, preparing documentations, implementing and realizing integrated management system. Also it is necessary to purify the conception of integrated management system in organizational context. Theoretical analysis of integrated management systems show, that all of the management systems can not be well integrated in principle. They can only be partly integrated and coordinated. A need to question the level of integration of managementsystems is very important as in scientific discourse as in practice. It is important to mark, that the number of organizations, that seek to optimize management processes by implementing the integrated management systems is rapidly increasing in Lithuania, too. It shows that benefit associated with integration of management systems is apprehensible in Lithuania. Advantages of integrated management systems can certainly become even stronger if scientists and practicians join their forces in search of methods of organizational management development.Research limitations. The research limitations related to a lack of integrated

  7. Integrated nutrients management for 'desi' cotton

    International Nuclear Information System (INIS)

    Qazi, M.A.; Akram, M.; Ahmad, N.; Khattak, M.A.

    2007-01-01

    Intensive cropping with no return of crop residues and other organic inputs result in the loss of soil organic matter (SOM) and nutrient supply in (Desi) cotton-wheat cropping system in Pakistan. For appraisal of problem and finding solution to sustainability, we evaluated six treatments comprised of two fertilizer doses and three management techniques over a period of three years (2003-05) monitoring their effects on seed cotton yield and soil fertility. The techniques included chemical fertilizers, municipal solid waste manure (MSWM) integrated with chemical fertilizers in 1:4 ratios with, and without pesticides. The results revealed that cotton yields. Were enhanced by 19% due to site-specific fertilizer dose over conventional dose. Ignoring weeds control by means of herbicided application resulted in 5% decrease of seed cotton yield in IPNM technique positive effect of MSWM integration was noted on soil test phosphorus and SOM. Site-specific fertilizer application and integrated plant nutrient management by MSWM proved their suitability as the techniques not only improve soil quality in terms of sustained levels of organic matter and phosphorus but also provide a safe way of waste disposal. (author)

  8. Towards integrated catchment management, Whaingaroa, New Zealand.

    Science.gov (United States)

    van Roon, M; Knight, S

    2001-01-01

    The paper examines progress towards integrated catchment management and sustainable agriculture at Whaingaroa (Raglan), New Zealand. Application of the Canadian "Atlantic Coastal Action Program" model (ACAP) has been only partially successful within New Zealand's bicultural setting. Even before the introduction of the ACAP process there existed strong motivation and leadership by various sectors of the community. A merging of resource management planning and implementation processes of the larger community and that of the Maori community has not occurred. Research carried out by Crown Research Institutes has clearly shown the actions required to make pastoral farming more sustainable. There are difficulties in the transference to, and uptake of, these techniques by farmers. An examination of the socio-economic context is required. There has been a requirement on local government bodies to tighten their focus as part of recent reform. This has occurred concurrently with a widening of vision towards integrated and sustainable forms of management. This (as well as a clear belief in empowerment of local communities) has lead to Council reliance on voluntary labour. There is a need to account for the dynamic interaction between social and political history and the geological and biophysical history of the area. As part of a re-examination of sustainable development, New Zealand needs to reconcile the earning of the bulk of its foreign income from primary production, with the accelerating ecological deficit that it creates. A sustainability strategy is required linking consumer demand, property rights and responsibilities.

  9. Integrating configuration workflows with project management system

    International Nuclear Information System (INIS)

    Nilsen, Dimitri; Weber, Pavel

    2014-01-01

    The complexity of the heterogeneous computing resources, services and recurring infrastructure changes at the GridKa WLCG Tier-1 computing center require a structured approach to configuration management and optimization of interplay between functional components of the whole system. A set of tools deployed at GridKa, including Puppet, Redmine, Foreman, SVN and Icinga, provides the administrative environment giving the possibility to define and develop configuration workflows, reduce the administrative effort and improve sustainable operation of the whole computing center. In this presentation we discuss the developed configuration scenarios implemented at GridKa, which we use for host installation, service deployment, change management procedures, service retirement etc. The integration of Puppet with a project management tool like Redmine provides us with the opportunity to track problem issues, organize tasks and automate these workflows. The interaction between Puppet and Redmine results in automatic updates of the issues related to the executed workflow performed by different system components. The extensive configuration workflows require collaboration and interaction between different departments like network, security, production etc. at GridKa. Redmine plugins developed at GridKa and integrated in its administrative environment provide an effective way of collaboration within the GridKa team. We present the structural overview of the software components, their connections, communication protocols and show a few working examples of the workflows and their automation.

  10. Integrated Global Nuclear Materials Management Preliminary Concepts

    International Nuclear Information System (INIS)

    Jones, E; Dreicer, M.

    2006-01-01

    The world is at a turning point, moving away from the Cold War nuclear legacy towards a future global nuclear enterprise; and this presents a transformational challenge for nuclear materials management. Achieving safety and security during this transition is complicated by the diversified spectrum of threat 'players' that has greatly impacted nonproliferation, counterterrorism, and homeland security requirements. Rogue states and non-state actors no longer need self-contained national nuclear expertise, materials, and equipment due to availability from various sources in the nuclear market, thereby reducing the time, effort and cost for acquiring a nuclear weapon (i.e., manifestations of latency). The terrorist threat has changed the nature of military and national security requirements to protect these materials. An Integrated Global Nuclear Materials Management (IGNMM) approach would address the existing legacy nuclear materials and the evolution towards a nuclear energy future, while strengthening a regime to prevent nuclear weapon proliferation. In this paper, some preliminary concepts and studies of IGNMM will be presented. A systematic analysis of nuclear materials, activities, and controls can lead to a tractable, integrated global nuclear materials management architecture that can help remediate the past and manage the future. A systems approach is best suited to achieve multi-dimensional and interdependent solutions, including comprehensive, end-to-end capabilities; coordinated diverse elements for enhanced functionality with economy; and translation of goals/objectives or standards into locally optimized solutions. A risk-informed basis is excellent for evaluating system alternatives and performances, and it is especially appropriate for the security arena. Risk management strategies--such as defense-in-depth, diversity, and control quality--help to weave together various technologies and practices into a strong and robust security fabric. Effective

  11. Water management as a key component of integrated weed management

    Directory of Open Access Journals (Sweden)

    Antonio Berti

    2010-09-01

    Full Text Available Water management within the cropping system is a key factor for an integrated weed management. Soil moisture affects seed persistence and seed dormancy, thus influencing their germination, the establishment of seedlings as well as the competition at adult stage and the number, vitality and dormancy of the new seeds produced by the weeds. The interactions among water availability and competition are very complex and still not fully understood. A research effort in this sector should the be very relevant for the development of new approaches of weed management, such as “Ecological weed management”, aiming to reduce weed density and competitiveness and, in the medium term, to prevent undesired modifications of the weed flora.

  12. Data integration for management of pipeline system integrity

    Energy Technology Data Exchange (ETDEWEB)

    Araujo, Anne A. de; Miranda, Ivan Vicente Janvrot; Silva, Jose Augusto Pereira da [Pipeway Engenharia, Rio de Janeiro, RJ (Brazil); Guimaraes, Frederico S; Magalhaes, Joao Alfredo P [Minds at Work, Rio de Janeiro, RJ (Brazil)

    2009-07-01

    The need to easily access pipeline information and the increasing number of inspections using distinct techniques from different vendors makes the use of systems in the Integrity Management Program indispensable. For this reason, MOPI has been developed by two Brazilian companies, Pipeway Engenharia in partnership with Minds at Work. This tool allows data recording from the design, construction and operation of the pipeline, the storage of documents, the comparison between the results of different inspections, the planning inspections, contracts and maintenance of the pipeline. Furthermore, the information registered in the system can be accessed by a network user without limitation of time or number of users. This work presents the main details and features of MOPI. (author)

  13. Rocket Testing and Integrated System Health Management

    Science.gov (United States)

    Figueroa, Fernando; Schmalzel, John

    2005-01-01

    Integrated System Health Management (ISHM) describes a set of system capabilities that in aggregate perform: determination of condition for each system element, detection of anomalies, diagnosis of causes for anomalies, and prognostics for future anomalies and system behavior. The ISHM should also provide operators with situational awareness of the system by integrating contextual and timely data, information, and knowledge (DIaK) as needed. ISHM capabilities can be implemented using a variety of technologies and tools. This chapter provides an overview of ISHM contributing technologies and describes in further detail a novel implementation architecture along with associated taxonomy, ontology, and standards. The operational ISHM testbed is based on a subsystem of a rocket engine test stand. Such test stands contain many elements that are common to manufacturing systems, and thereby serve to illustrate the potential benefits and methodologies of the ISHM approach for intelligent manufacturing.

  14. Strategic Environmental Assessment: Integrated environmental management

    CSIR Research Space (South Africa)

    Department of Environmental Affairs and Tourism

    2004-01-01

    Full Text Available stream_source_info Department of Environmental Affairs and Tourism_2004.pdf.txt stream_content_type text/plain stream_size 70155 Content-Encoding ISO-8859-1 stream_name Department of Environmental Affairs and Tourism_2004.pdf... and Tourism Other topics in the series of overview information documents on the concepts of, and approaches to, integrated environmental management are listed below. Further titles in this series are being prepared and will be made available periodically...

  15. FEMA's Integrated Emergency Management Information System (IEMIS)

    International Nuclear Information System (INIS)

    Jaske, R.T.; Meitzler, W.

    1987-01-01

    FEMA is implementing a computerized system for use in optimizing planning, and for supporting exercises of these plans. Called the Integrated Emergency Management Information System (IEMIS), it consists of a base geographic information system upon which analytical models are superimposed in order to load data and report results analytically. At present, it supports FEMA's work in offsite preparedness around nuclear power stations, but is being developed to deal with a full range of natural and technological accident hazards for which emergency evacuation or population movement is required

  16. Integrate offsites management with information systems

    Energy Technology Data Exchange (ETDEWEB)

    Valleur, M. (TECHNIP, Paris (France))

    1993-11-01

    Computerized offsites management systems in oil refineries offer a unique opportunity to integrate advanced technology into a coherent refinery information system that contributes to benefits-driven optimal operations: from long-term, multirefinery linear programming (LP) models to sequential control of transfer lineups in the tank farm. There are strong incentives to automate and optimize the offsites operations, and benefits can be quantified to justify properly sized projects. The paper discusses the following: business opportunities, oil movement and advanced technology, project scoping and sizing, review of functional requirements, transfer automation, blending optimal control, on-line analyzers, oil movement and scheduling, organizational issues, and investment and benefits analysis.

  17. Integrated solid waste management of Seattle, Washington

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-11-01

    The subject document reports the results of an in-depth investigation of the fiscal year 1992 cost of the City of Seattle, Washington, integrated municipal solid waste management (IMSWM) system, the energy consumed to operate the system, and the environmental performance requirements for each of the system`s waste-processing and disposal facilities. Actual data from records kept by participants is reported in this document. Every effort was made to minimize the use of assumptions, and no attempt is made to interpret the data reported. Analytical approaches are documented so that interested analysts may perform manipulation or further analysis of the data. As such, the report is a reference document for MSW management professionals who are interested in the actual costs and energy consumption for a one-year period, of an operating IMSWM systems.

  18. Integrated solid waste management of Minneapolis, Minnesota

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-11-01

    The subject document reports the results of an in-depth investigation of the fiscal year 1992 cost of the City of Minneapolis, Minnesota (Hennepin County) integrated municipal solid waste management (IMSWM) system, the energy consumed to operate the system, and the environmental performance requirements for each of the system`s waste-processing and disposal facilities. Actual data from records kept by participants is reported in this document. Every effort was made to minimize the use of assumptions, and no attempt is made to interpret the data reported. Analytical approaches are documented so that interested analysts may perform manipulation or further analysis of the data. As such, the report is a reference document for municipal solid waste (MSW) management professionals who are interested in the actual costs and energy consumption for a one-year period, of an operating IMSWM system.

  19. Integrated solid waste management of Sevierville, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-11-01

    The subject document reports the results of an in-depth investigation of the fiscal year 1992 cost of the City of Sevierville, Tennessee integrated municipal solid waste management (IMSWM) system, the energy consumed to operate the system, and the environmental performance requirements for each of the system`s waste-processing and disposal facilities. Actual data from records kept by participants is reported in this document. Every effort was made to minimize the use of assumptions, and no attempt is made to interpret the data reported. Analytical approaches are documented so that interested analysts may perform manipulation or further analysis of the data. As such, the report is a reference document for MSW management professionals who are interested in the actual costs and energy consumption for a one-year period, of an operating IMSWM systems.

  20. Partnership - the heart of integrated outage management

    International Nuclear Information System (INIS)

    Robinson, F.T.

    1995-01-01

    Changes in the power generating industry continue apace. The effects of privatisation are widely visible: nowhere more so than in the growing national and international competition facing the generators around the world. A successful, long-term marriage between generator and contractor on power station outage management offers significant scope for cost reduction, shortening annual plant downtime and generating more megawatts, all within a safety environment of continuous improvement. Working in close partnership, Nuclear Electric and Rolls-Royce Nuclear Engineering Services have remodelled the whole contractor/client strategy. The new discipline, known as integrated outage management and partnering, is already producing shorter outage periods at Bradwell, a Magnox Station in Essex. (author)

  1. RISK MANAGEMENT: AN INTEGRATED APPROACH TO RISK MANAGEMENT AND ASSESSMENT

    Directory of Open Access Journals (Sweden)

    Szabo Alina

    2012-12-01

    Full Text Available Purpose: The objective of this paper is to offer an overview over risk management cycle by focusing on prioritization and treatment, in order to ensure an integrated approach to risk management and assessment, and establish the ‘top 8-12’ risks report within the organization. The interface with Internal Audit is ensured by the implementation of the scoring method to prioritize risks collected from previous generated risk report. Methodology/approach: Using evidence from other research in the area and the professional expertise, this article outlines an integrated approach to risk assessment and risk management reporting processes, by separating the risk in two main categories: strategic and operational risks. The focus is on risk prioritization and scoring; the final output will comprise a mix of strategic and operational (‘top 8-12’ risks, which should be used to establish the annual Internal Audit plan. Originality/value: By using an integrated approach to risk assessment and risk management will eliminate the need for a separate Internal Audit risk assessment over prevailing risks. It will reduce the level of risk assessment overlap by different functions (Tax, Treasury, Information System over the same risk categories as a single methodology, is used and will align timings of risk assessment exercises. The risk prioritization by usage of risk and control scoring criteria highlights the combination between financial and non-financial impact criteria allowing risks that do not naturally lend themselves to a financial amount to be also assessed consistently. It is emphasized the usage of score method to prioritize the risks included in the annual audit plan in order to increase accuracy and timelines.

  2. Integrated solid waste management in Japan

    Energy Technology Data Exchange (ETDEWEB)

    Cohen, A.S. [CSI Resource Systems, Boston, MA (United States)

    1993-12-31

    The Japanese, through a combination of public policy, private market conditions, and geographic necessity, practice integrated municipal solid waste management as defined by the US Environmental Protection Agency. The Japanese have not defined a specific hierarchical preference for alternative waste management practices, i.e., waste reduction, reuse and recycling, combustion, composting, and landfill disposal. However, in marked contrast to the US approach, the Japanese system relies heavily on waste combustion, with and without energy recovery. {open_quotes}Discards{close_quotes}, as the term is used in this paper, refers to all materials considered used and spent by residential and commercial generators. That which is discarded (whether recyclable or nonrecyclable) by a municipality is referred to as MSW. This paper provides an overview of MSW management practices and private-sector recycling in Japan. Estimates of the total generation of residential and commercial discards and their disposition are also presented. Such an overview of Japanese practices can be used to assess the potential effectiveness of US integrated solid waste management programs. Of the estimated 61.3 to 72.1 million tons of residential and commercial discards generated in Japan during its 1989 fiscal year (April 1, 1989, through March 31, 1990), an estimated 55 to 64 percent was incinerated; 15 to 28 percent was recycled (only 2 to 3 percent through municipal recycling activities); less than 0.1 percent was composted or used as animal feed; and 17 to 20 percent was landfilled. Including ash disposal, 26 to 30 percent, by weight, of the gross discards were landfilled.

  3. Economic evaluation of an area-wide integrated pest management program to control the Asian tiger mosquito in New Jersey

    Science.gov (United States)

    Aedes albopictus is the most invasive mosquito in the world, an important disease vector, and a biting nuisance that limits outdoor activities. Area-wide integrated pest management (AW-IPM) is the recommended control strategy. We conducted an economic evaluation of the AW-IPM project in Mercer and ...

  4. Integrated water resources management using engineering measures

    Science.gov (United States)

    Huang, Y.

    2015-04-01

    The management process of Integrated Water Resources Management (IWRM) consists of aspects of policies/strategies, measures (engineering measures and non-engineering measures) and organizational management structures, etc., among which engineering measures such as reservoirs, dikes, canals, etc., play the backbone that enables IWRM through redistribution and reallocation of water in time and space. Engineering measures are usually adopted for different objectives of water utilization and water disaster prevention, such as flood control and drought relief. The paper discusses the planning and implementation of engineering measures in IWRM of the Changjiang River, China. Planning and implementation practices of engineering measures for flood control and water utilization, etc., are presented. Operation practices of the Three Gorges Reservoir, particularly the development and application of regulation rules for flood management, power generation, water supply, ecosystem needs and sediment issues (e.g. erosion and siltation), are also presented. The experience obtained in the implementation of engineering measures in Changjiang River show that engineering measures are vital for IWRM. However, efforts should be made to deal with changes of the river system affected by the operation of engineering measures, in addition to escalatory development of new demands associated with socio-economic development.

  5. Integrated water resources management using engineering measures

    Directory of Open Access Journals (Sweden)

    Y. Huang

    2015-04-01

    Full Text Available The management process of Integrated Water Resources Management (IWRM consists of aspects of policies/strategies, measures (engineering measures and non-engineering measures and organizational management structures, etc., among which engineering measures such as reservoirs, dikes, canals, etc., play the backbone that enables IWRM through redistribution and reallocation of water in time and space. Engineering measures are usually adopted for different objectives of water utilization and water disaster prevention, such as flood control and drought relief. The paper discusses the planning and implementation of engineering measures in IWRM of the Changjiang River, China. Planning and implementation practices of engineering measures for flood control and water utilization, etc., are presented. Operation practices of the Three Gorges Reservoir, particularly the development and application of regulation rules for flood management, power generation, water supply, ecosystem needs and sediment issues (e.g. erosion and siltation, are also presented. The experience obtained in the implementation of engineering measures in Changjiang River show that engineering measures are vital for IWRM. However, efforts should be made to deal with changes of the river system affected by the operation of engineering measures, in addition to escalatory development of new demands associated with socio-economic development.

  6. Managing Uncertainty for an Integrated Fishery

    Directory of Open Access Journals (Sweden)

    MB Hasan

    2012-06-01

    Full Text Available This paper investigates ways to deal with the uncertainties in fishing trawler scheduling and production planning in a quota-based integrated commercial fishery. A commercial fishery faces uncertainty mainly from variation in catch rate, which may be due to weather, and other environmental factors. The firm tries to manage this uncertainty through planning co-ordination of fishing trawler scheduling, catch quota, processing and labour allocation, and inventory control. Scheduling must necessarily be done over some finite planning horizon, and the trawler schedule itself introduces man-made variability, which in turn induces inventory in the processing plant. This induced inventory must be managed, complicated by the inability to plan easily beyond the current planning horizon. We develop a surprisingly simple innovation in inventory, which we have not seen in other papers on production management, which of requiring beginning inventory to equal ending inventory. This tool gives management a way to calculate a profit-maximizing safety stock that counter-acts the man-made variability due to the trawler scheduling. We found that the variability of catch rate had virtually no effects on the profitability with inventory. We report numerical results for several planning horizon models, based on data for a major New Zealand fishery.

  7. Planning construction of integrative schedule management for nuclear power project

    International Nuclear Information System (INIS)

    Zeng Zhenglin; Wang Wenying; Peng Fei

    2012-01-01

    This paper introduces the planning construction of integrative schedule management for Nuclear Power Project. It details schedule management system and the requirement of schedulers and the mode of three schedule management flats. And analysis it combing with the implementation of construction water and all special schedules before FCD to further propose the improving and researching direction for the integrative schedule management. (authors)

  8. Climate change and integrated water resources management

    International Nuclear Information System (INIS)

    Bhuiyan, Nurul Amin

    2007-01-01

    Full text: Full text: In the Bangladesh Poverty Reduction Strategy (PRSP), Millennium Development Goals and other donor driven initiatives, two vital areas linked with poverty and ecosystem survival seem to be either missing or are being neglected: (a) transboundary water use and (b) coastal area poverty and critical ecosystems vulnerable due to climate change. Since the World Summit on Sustainable Development (WSSD) goals and PRSP are integrated, it is necessary that the countrys WSSD goals and PRSP should also be in harmony. All should give the recognition of Ganges Brahmaputra and Meghna as international basins and the approach should be taken for regional sustainable and integrated water resource management involving all co-riparian countries. The principle of low flow in the international rivers during all seasons should be ensured. All stakeholders should have a say and work towards regional cooperation in the water sector as a top priority. The energy sector should be integrated with water. The Indian River Linking project involving international rivers should be seriously discussed at all levels including the parliament so that voice of Bangladesh is concerted and information shared by all concerned. One of the most critical challenges Bangladesh faces is the management of water resources during periods of water excesses and acute scarcity. It is particularly difficult when only 7% of the catchments areas of the very international rivers, the Ganges, the Brahmaputra and the Meghna are in Bangladesh while 97% is outside Bangladesh where unfortunately, Bangladesh has no control on upstream diversion and water use. The UN Conference on Environment and Development in its Agenda 21 emphasizes the importance of Integrated Water Resource Management (IWRM). The core point of IWRM is that is development of all aspects of entire basin in a basin wide approach, that all relevant agencies of the government and water users must be involved in the planning process and

  9. Deletion of the LTR enhancer/promoter has no impact on the integration profile of MLV vectors in human hematopoietic progenitors.

    Directory of Open Access Journals (Sweden)

    Arianna Moiani

    Full Text Available Moloney murine leukemia virus (MLV-derived gamma-retroviral vectors integrate preferentially near transcriptional regulatory regions in the human genome, and are associated with a significant risk of insertional gene deregulation. Self-inactivating (SIN vectors carry a deletion of the U3 enhancer and promoter in the long terminal repeat (LTR, and show reduced genotoxicity in pre-clinical assays. We report a high-definition analysis of the integration preferences of a SIN MLV vector compared to a wild-type-LTR MLV vector in the genome of CD34(+ human hematopoietic stem/progenitor cells (HSPCs. We sequenced 13,011 unique SIN-MLV integration sites and compared them to 32,574 previously generated MLV sites in human HSPCs. The SIN-MLV vector recapitulates the integration pattern observed for MLV, with the characteristic clustering of integrations around enhancer and promoter regions associated to H3K4me3 and H3K4me1 histone modifications, specialized chromatin configurations (presence of the H2A.Z histone variant and binding of RNA Pol II. SIN-MLV and MLV integration clusters and hot spots overlap in most cases and are generated at a comparable frequency, indicating that the reduced genotoxicity of SIN-MLV vectors in hematopoietic cells is not due to a modified integration profile.

  10. Integrated Space Asset Management Database and Modeling

    Science.gov (United States)

    MacLeod, Todd; Gagliano, Larry; Percy, Thomas; Mason, Shane

    2015-01-01

    Effective Space Asset Management is one key to addressing the ever-growing issue of space congestion. It is imperative that agencies around the world have access to data regarding the numerous active assets and pieces of space junk currently tracked in orbit around the Earth. At the center of this issues is the effective management of data of many types related to orbiting objects. As the population of tracked objects grows, so too should the data management structure used to catalog technical specifications, orbital information, and metadata related to those populations. Marshall Space Flight Center's Space Asset Management Database (SAM-D) was implemented in order to effectively catalog a broad set of data related to known objects in space by ingesting information from a variety of database and processing that data into useful technical information. Using the universal NORAD number as a unique identifier, the SAM-D processes two-line element data into orbital characteristics and cross-references this technical data with metadata related to functional status, country of ownership, and application category. The SAM-D began as an Excel spreadsheet and was later upgraded to an Access database. While SAM-D performs its task very well, it is limited by its current platform and is not available outside of the local user base. Further, while modeling and simulation can be powerful tools to exploit the information contained in SAM-D, the current system does not allow proper integration options for combining the data with both legacy and new M&S tools. This paper provides a summary of SAM-D development efforts to date and outlines a proposed data management infrastructure that extends SAM-D to support the larger data sets to be generated. A service-oriented architecture model using an information sharing platform named SIMON will allow it to easily expand to incorporate new capabilities, including advanced analytics, M&S tools, fusion techniques and user interface for

  11. Integrating workflow and project management systems for PLM applications

    Directory of Open Access Journals (Sweden)

    Fabio Fonseca Pereira de Paula

    2008-07-01

    Full Text Available The adoption of Product Life-cycle Management Systems (PLMs concept is fundamental to improve the product development, mainly to small and medium enterprises (SMEs. One of the challenges is the integration between project management and product data management functions. The paper presents an analysis of the potential integration strategies for a specifics product data management system (SMARTEAM and a project management system (Microsoft Project, which are commonly used for SMEs. Finally the article presents some considerations about the study of Project Management solutions in SMB’s companies, considering the PLM approach. Key-words: integration, project management (PM, workflow, PDM, PLM.

  12. Rigid Body Time Integration by Convected Base Vectors with Implicit Constraints

    DEFF Research Database (Denmark)

    Krenk, Steen; Nielsen, Martin Bjerre

    2013-01-01

    of the kinetic energy used in the present formulation is deliberately chosen to correspond to a rigid body rotation, and the orthonormality constraints are introduced via the equivalent Green strain components of the base vectors. The particular form of the extended inertia tensor used here implies a set...

  13. Testing for Co-integration in Vector Autoregressions with Non-Stationary Volatility

    DEFF Research Database (Denmark)

    Cavaliere, Guiseppe; Rahbæk, Anders; Taylor, A.M. Robert

    Many key macro-economic and financial variables are characterised by permanent changes in unconditional volatility. In this paper we analyse vector autoregressions with non-stationary (unconditional) volatility of a very general form, which includes single and multiple volatility breaks as special...

  14. Testing for Co-integration in Vector Autoregressions with Non-Stationary Volatility

    DEFF Research Database (Denmark)

    Cavaliere, Giuseppe; Rahbek, Anders Christian; Taylor, A. M. Robert

    Many key macro-economic and …nancial variables are characterised by permanent changes in unconditional volatility. In this paper we analyse vector autoregressions with non-stationary (unconditional) volatility of a very general form, which includes single and multiple volatility breaks as special...

  15. Integrated malaria vector control in different agro-ecosystems in western Kenya

    NARCIS (Netherlands)

    Imbahale, S.S.

    2009-01-01

    Malaria is a complex disease and its transmission is a function of the interaction between the Anopheles mosquito vector, the Plasmodium parasite, the hosts and the environment. Malaria control has mainly targeted the Plasmodium parasite or the adult anopheline mosquitoes. However, development of

  16. Two-loop planar master integrals for the production of off-shell vector bosons in hadron collisions

    International Nuclear Information System (INIS)

    Henn, Johannes M.; Melnikov, Kirill; Smirnov, Vladimir A.

    2014-01-01

    We describe the calculation of all planar master integrals that are needed for the computation of NNLO QCD corrections to the production of two off-shell vector bosons in hadron collisions. The most complicated representatives of integrals in this class are the two-loop four-point functions where two external lines are on the light-cone and two other external lines have different invariant masses. We compute these and other relevant integrals analytically using differential equations in external kinematic variables and express our results in terms of Goncharov polylogarithms. The case of two equal off-shellnesses, recently considered in ref. http://dx.doi.org/10.1007/JHEP08(2013)070, appears as a particular case of our general solution

  17. Integrated Work Management: FOD/RLM, Course 31882

    Energy Technology Data Exchange (ETDEWEB)

    Simpson, Lewis Edward [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-08-07

    The facility operations director (FOD) and responsible line manager (RLM) play leadership and functional roles in the integrated work management (IWM) process at Los Alamos National Laboratory (LANL). This course, Integrated Work Management: FOD/RLM (COURSE 31882), describes the IWM roles and responsibilities of the FOD and the RLM; it also discusses IWM requirements that must be met by the FOD and the RLM. Before taking this course, you may want to take COURSE 31881, Integrated Work Management: Overview. This self-study course would be particularly helpful if you are unfamiliar with the IWM process. You should also read Procedure (P) 300, Integrated Work Management. This course briefly covers the roles of the preparer and person in charge (PIC). For more in-depth instruction on the preparer’s role, see COURSE 31883, Integrated Work Management: Preparer. For instruction on the PIC’s role, see COURSE 31884, Integrated Work Management: PIC.

  18. Managing racial integration in South African public schools: In ...

    African Journals Online (AJOL)

    The paper explores what racial integration is. Furthermore, it scrutinises how racial integration is currently managed in South African Public schools. The main argument of the paper defends a deliberative conception of managing racial integration in South African public schools. In light of this, there is some form of hope to ...

  19. Integrated System Health Management (ISHM) and Autonomy

    Science.gov (United States)

    Figueroa, Fernando; Walker, Mark G.

    2018-01-01

    Systems capabilities on ISHM (Integrated System Health Management) and autonomy have traditionally been addressed separately. This means that ISHM functions, such as anomaly detection, diagnostics, prognostics, and comprehensive system awareness have not been considered traditionally in the context of autonomy functions such as planning, scheduling, and mission execution. One key reason is that although they address systems capabilities, both ISHM and autonomy have traditionally individually been approached as independent strategies and models for analysis. Additionally, to some degree, a unified paradigm for ISHM and autonomy has been difficult to implement due to limitations of hardware and software. This paper explores a unified treatment of ISHM and autonomy in the context of distributed hierarchical autonomous operations.

  20. Integrated pest management of "Golden Delicious" apples.

    Science.gov (United States)

    Simončič, A; Stopar, M; Velikonja Bolta, Š; Bavčar, D; Leskovšek, R; Baša Česnik, H

    2015-01-01

    Monitoring of plant protection product (PPP) residues in "Golden Delicious" apples was performed in 2011-2013, where 216 active substances were analysed with three analytical methods. Integrated pest management (IPM) production and improved IPM production were compared. Results were in favour of improved IPM production. Some active compounds determined in IPM production (boscalid, pyraclostrobin, thiacloprid and thiametoxam) were not found in improved IPM production. Besides that, in 2011 and 2012, captan residues were lower in improved IPM production. Risk assessment was also performed. Chronic exposure of consumers was low in general, but showed no major differences for IPM and improved IPM production for active substances determined in both types of production. Analytical results were compared with the European Union report of 2010 where 1.3% of apple samples exceeded maximum residue levels (MRLs), while MRL exceedances were not observed in this survey.

  1. The Management of Law Firms Using Business Process Management, Document Management and Web Services Integration

    OpenAIRE

    Roxana Maria Petculet

    2012-01-01

    The aim of this paper is to present the technical solution implemented in the present context for the management of law firms. The informational system consists of the automation of business processes using a BPM engine and electronic archiving using a DMS. The communication between the two modules is made by invoking web services. The whole system integrates modules like: project management, contract management, invoice management, collection, CRM, reporting.

  2. Integrated solid waste management of Scottsdale, Arizona

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-11-01

    The subject document reports the results of an in-depth investigation of the fiscal year 1992 cost of the city of Scottsdale, Arizona, integrated municipal solid waste management (IMSWM) system, the energy consumed to operate the system, and the environmental performance requirements for each of the system`s waste-processing and disposal facilities. The document reports actual data from records kept by participants. Every effort was made to minimize the use of assumptions, and no attempt is made to interpret the data reported. Analytical approaches are documented so that interested analysts may per-form manipulation or further analysis of the data. As such, the report is a reference document for municipal solid waste (MSW) management professionals who are interested in the actual costs and energy consumption, for a 1-year period, of an operating IMSWM system. The report is organized into two main parts. The first part is the executive summary and case study portion of the report. The executive summary provides a basic description of the study area and selected economic and energy information. Within the case study are detailed descriptions of each component operating during the study period; the quantities of solid waste collected, processed, and marketed within the study boundaries; the cost of MSW in Scottsdale; an energy usage analysis; a review of federal, state, and local environmental requirement compliance; a reference section; and a glossary of terms. The second part of the report focuses on a more detailed discourse on the above topics. In addition, the methodology used to determine the economic costs and energy consumption of the system components is found in the second portion of this report. The methodology created for this project will be helpful for those professionals who wish to break out the costs of their own integrated systems.

  3. Efficacy and evaluation of environmental management system to control sandfly vector of Kala-azar.

    Science.gov (United States)

    Dinesh, D S; Kumari, S; Hassan, F; Kumar, V; Singh, V P; Das, P

    2017-10-01

    The established vector for visceral leishmaniasis, Phlebotomus argentipes (Diptera: Psychodidae) breeds inside the human dwellings and cattle shed under crevices at the base of the wall. P. argentipes was controlled by plastering the base of wall (9″height × 9″base). The study was conducted in two phases: (i) Screening of plastering materials (ii) validation of the most suitable material. During the first phase (2014); four intervention materials were evaluated in four different arms: (i) cement (ii) brick chimney fly ash (BCFA i.e. waste material from an oven for backing raw earthen brick in charcoal) mixed with lime (95:5) (iii) wire mesh (25 holes/cm 2 ) and (iv) glazed tiles. Ten houses were selected as test and same as control in four different villages for each arm having similar ecotype and similar density of sandflies. The pre and post intervention density of sandflies were evaluated. Significant reduction in sandfly density was found with cement (46.2%) and BCFA (29.6%) plastering (P < 0.05). In the second phase of the study (2015); the two most effective interventions were validated at village level with one control. A significant reduction in the density of P. argentipes was found with cement; 60.2% (Mean ± S.D. = 2.48 ± 2.78, 95% CI = 1.93-3.02) and BCFA; 48.2% (Mean ± S.D. = 1.98 ± 2.20, 95% CI = 1.55-2.41) (P < 0.05). BCFA was found easily accessible, acceptable and cost effective that can be used in any type of wall materials at own cost. This can be implemented as one of the integrated vector control approach in the programme. Copyright © 2017. Published by Elsevier Ltd.

  4. Energy efficiency through integrated environmental management.

    Science.gov (United States)

    Benromdhane, Souad Ahmed

    2015-05-01

    Integrated environmental management became an economic necessity after industrial development proved to be unsustainable without consideration of environmental direct and indirect impacts. Energy dependency and air pollution along with climate change grew into major challenges facing developed and developing countries alike. Thus, a new global market structure emerged and changed the way we do trade. The search intensified for alternatives to petroleum. However, scientists, policy makers, and environmental activists agreed to focus on strategic conservation and optimization of energy use. Environmental concerns will remain partially unaddressed with the current pace of consumption because greenhouse gas emissions will continue to rise with economic growth. This paper discusses energy efficiency, steady integration of alternative sources, and increased use of best available technologies. Energy criteria developed for environmental labeling certification are presented. Our intention is to encourage manufacturers and service providers to supply consumers with less polluting and energy-consuming goods and services, inform consumers of the environmental and energy impacts, and thereby instill sustainable and responsible consumption. As several programs were initiated in developed countries, environmental labeling requirements created barriers to many exports manufactured in developing countries, affecting current world trade and putting more pressure on countries to meet those requirements. Defining an institutional and legal framework of environmental labeling is a key challenge in implementing such programs for critical economic sectors like tourism, textiles, and food production where energy needs are the most important aspect to control. A case study of Tunisia and its experience with eco-labeling is presented.

  5. Integrated remotely sensed datasets for disaster management

    Science.gov (United States)

    McCarthy, Timothy; Farrell, Ronan; Curtis, Andrew; Fotheringham, A. Stewart

    2008-10-01

    Video imagery can be acquired from aerial, terrestrial and marine based platforms and has been exploited for a range of remote sensing applications over the past two decades. Examples include coastal surveys using aerial video, routecorridor infrastructures surveys using vehicle mounted video cameras, aerial surveys over forestry and agriculture, underwater habitat mapping and disaster management. Many of these video systems are based on interlaced, television standards such as North America's NTSC and European SECAM and PAL television systems that are then recorded using various video formats. This technology has recently being employed as a front-line, remote sensing technology for damage assessment post-disaster. This paper traces the development of spatial video as a remote sensing tool from the early 1980s to the present day. The background to a new spatial-video research initiative based at National University of Ireland, Maynooth, (NUIM) is described. New improvements are proposed and include; low-cost encoders, easy to use software decoders, timing issues and interoperability. These developments will enable specialists and non-specialists collect, process and integrate these datasets within minimal support. This integrated approach will enable decision makers to access relevant remotely sensed datasets quickly and so, carry out rapid damage assessment during and post-disaster.

  6. MAST's Integrated Data Access Management system: IDAM

    International Nuclear Information System (INIS)

    Muir, D.G.; Appel, L.; Conway, N.J.; Kirk, A.; Martin, R.; Meyer, H.; Storrs, J.; Taylor, D.; Thomas-Davies, N.; Waterhouse, J.

    2008-01-01

    A new Integrated Data Access Management system, IDAM, has been created to address specific data management issues of the MAST spherical Tokamak. For example, this system enables access to numerous file formats, both legacy and modern (IDA, Ufile, netCDF, HDF5, MDSPlus, PPF, JPF). It adds data quality values at the signal level, and automatically corrects for problems in data: in timings, calibrations, and labelling. It also builds new signals from signal components. The IDAM data server uses a hybrid XML-relational database to record how data are accessed, whether locally or remotely, and how alias and generic signal names are mapped to true names. Also, XML documents are used to encode the details of data corrections, as well as definitions of composite signals and error models. The simple, user friendly, API and accessor function library, written in C on Linux, is available for applications in C, C++, IDL and Fortran-90/95/2003 with good performance: a MAST plasma current trace (28 kbytes of data), requested using a generic name and with data corrections applied, is delivered over a 100 Mbit/s network in ∼13 ms

  7. Integrated Traffic Flow Management Decision Making

    Science.gov (United States)

    Grabbe, Shon R.; Sridhar, Banavar; Mukherjee, Avijit

    2009-01-01

    A generalized approach is proposed to support integrated traffic flow management decision making studies at both the U.S. national and regional levels. It can consider tradeoffs between alternative optimization and heuristic based models, strategic versus tactical flight controls, and system versus fleet preferences. Preliminary testing was accomplished by implementing thirteen unique traffic flow management models, which included all of the key components of the system and conducting 85, six-hour fast-time simulation experiments. These experiments considered variations in the strategic planning look-ahead times, the replanning intervals, and the types of traffic flow management control strategies. Initial testing indicates that longer strategic planning look-ahead times and re-planning intervals result in steadily decreasing levels of sector congestion for a fixed delay level. This applies when accurate estimates of the air traffic demand, airport capacities and airspace capacities are available. In general, the distribution of the delays amongst the users was found to be most equitable when scheduling flights using a heuristic scheduling algorithm, such as ration-by-distance. On the other hand, equity was the worst when using scheduling algorithms that took into account the number of seats aboard each flight. Though the scheduling algorithms were effective at alleviating sector congestion, the tactical rerouting algorithm was the primary control for avoiding en route weather hazards. Finally, the modeled levels of sector congestion, the number of weather incursions, and the total system delays, were found to be in fair agreement with the values that were operationally observed on both good and bad weather days.

  8. Wheel speed management control system for spacecraft

    Science.gov (United States)

    Goodzeit, Neil E. (Inventor); Linder, David M. (Inventor)

    1991-01-01

    A spacecraft attitude control system uses at least four reaction wheels. In order to minimize reaction wheel speed and therefore power, a wheel speed management system is provided. The management system monitors the wheel speeds and generates a wheel speed error vector. The error vector is integrated, and the error vector and its integral are combined to form a correction vector. The correction vector is summed with the attitude control torque command signals for driving the reaction wheels.

  9. Integrated NPP life cycle management - Agency's approach

    International Nuclear Information System (INIS)

    Gueorguiev, B.

    2002-01-01

    Full text: The number of nuclear power plants (NPPs) operating in the world has been roughly constant for the past seven years. There are 438 reactors of 353,489 MW(e) capacity in the world and they generated 2448.9 TWh in 2001 giving a total world operating experience with nuclear power of 10,363 years. About 230 units have reached already over 15 years of operation and significant number of these plants are fully depreciated. Share of nuclear power in electricity production sector in Member States utilising nuclear power plants represents a meaningful amount and in 14 countries it exceeds 30%. Therefore, a loss of this share should be covered by new installed capacities either from conventional or alternative sources of electricity generation. Recent forecasts, for nuclear power use over the next two decades range from ∼350 to ∼500 GW(e) worldwide. While assessing the need for any nuclear power related programmes there are several important factors that must be considered since even 350 GW(e) is a very large programme requiring several hundred thousand highly qualified personnel and a substantial infrastructure to assure its continued safe, reliable and cost-effective operation. It is important to assure reliable, safe and economic beneficial performance of the plant, which requires in turn an appropriated management of any activity connected with any taken period of a plant life starting from design and ending by the decided mode of decommissioning. The period between the first and the last payment for the activities connected with the existence of a plant could be defined as a life cycle of the plant. Such integrated approach requires considering the life cycle of the plant in a much broader sense than just operational life and is characterized by the variety of activities and their management represents in a whole a plant life management programme (PLIM). Therefore PLIM could be defined as an aggregate (totality) of technical, financial, economical and

  10. VECTORS of change in the marine environment: Ecosystem and economic impacts and management implications

    Science.gov (United States)

    Austen, M. C.; Crowe, T. P.; Elliott, M.; Paterson, D. M.; Peck, M. A.; Piraino, S.

    2018-02-01

    Human use of the European marine environment is increasing and diversifying. This is creating new mechanisms for human induced-changes in marine life which need to be understood and quantified as well as the impact of these changes on ecosystems, their structures (e.g. biodiversity) and functioning (e.g. productivity), and the social and economic consequences that arise. The current and emerging pressures are multiple and interacting, arising, for example, from transport, platforms for renewable and non-renewable energy, exploitation of living and non-living resources, agricultural and industrial discharges, together with wider environmental changes (including climate change). Anticipating the future consequences of these pressures and vectors of change for marine life and of adaptation and mitigation measures (such as the introduction of new technologies and structures, new ballast water practices, ocean and offshore wind energy devices and new fishing strategies) is a prerequisite to the development and implementation of strategies, policies and regulations to manage the marine environment, such as the IMO Convention on ballast water management and the EU Maritime Policy and Marine Strategy Framework Directive.

  11. Weather information integration in transportation management center (TMC) operations.

    Science.gov (United States)

    2011-01-02

    This report presents the results of the third phase of an on-going FHWA study on weather integration in Transportation Management Center (TMC) operations. The report briefly describes the earlier phases of the integration study, summarizes the findin...

  12. integrated identity and integrated identity and access management

    African Journals Online (AJOL)

    eobe

    Management System (T-IAMS) is a fingerprint biometric database that centrally manages students' identity, course a fingerprint ... registration, library and medical services information. .... based application and a web-based application.

  13. The integrity management cycle as a business process

    Energy Technology Data Exchange (ETDEWEB)

    Ackhurst, Trent B.; Peverelli, Romina P. [PIMS - Pipeline Integrity Management Specialists of London Ltd. (United Kingdom).

    2009-07-01

    It is a best-practice Oil and Gas pipeline integrity and reliability technique to apply integrity management cycles. This is conforms to the business principles of continuous improvement. This paper examines the integrity management cycle - both goals and objectives and subsequent component steps - from a business perspective. Traits that businesses require, to glean maximum benefit from such a cycle, are highlighted. A case study focuses upon an integrity and reliability process developed to apply to pipeline operators. installations. This is compared and contrasted to the pipeline integrity management cycle to underline both cycles. consistency with the principles of continuous improvement. (author)

  14. Integrated Weed Management Strategies for Control of Hydrilla

    National Research Council Canada - National Science Library

    Nelson, Linda S; Shearer, Judy F

    2009-01-01

    ...), and the fungal pathogen Mycoleptodiscus terrestris (Gerd.) Ostazeski, applied alone and in combination with one another, as an integrated weed management strategy against the nuisance aquatic plant, hydrilla...

  15. Community mobilization and household level waste management for dengue vector control in Gampaha district of Sri Lanka; an intervention study.

    Science.gov (United States)

    Abeyewickreme, W; Wickremasinghe, A R; Karunatilake, K; Sommerfeld, J; Axel, Kroeger

    2012-12-01

    Waste management through community mobilization to reduce breeding places at household level could be an effective and sustainable dengue vector control strategy in areas where vector breeding takes place in small discarded water containers. The objective of this study was to assess the validity of this assumption. An intervention study was conducted from February 2009 to February 2010 in the populous Gampaha District of Sri Lanka. Eight neighborhoods (clusters) with roughly 200 houses each were selected randomly from high and low dengue endemic areas; 4 of them were allocated to the intervention arm (2 in the high and 2 in the low endemicity areas) and in the same way 4 clusters to the control arm. A baseline household survey was conducted and entomological and sociological surveys were carried out simultaneously at baseline, at 3 months, at 9 months and at 15 months after the start of the intervention. The intervention programme in the treatment clusters consisted of building partnerships of local stakeholders, waste management at household level, the promotion of composting biodegradable household waste, raising awareness on the importance of solid waste management in dengue control and improving garbage collection with the assistance of local government authorities. The intervention and control clusters were very similar and there were no significant differences in pupal and larval indices of Aedes mosquitoes. The establishment of partnerships among local authorities was well accepted and sustainable; the involvement of communities and households was successful. Waste management with the elimination of the most productive water container types (bowls, tins, bottles) led to a significant reduction of pupal indices as a proxy for adult vector densities. The coordination of local authorities along with increased household responsibility for targeted vector interventions (in our case solid waste management due to the type of preferred vector breeding places) is

  16. Integrated mapping of establishment risk for emerging vector-borne infections: a case study of canine leishmaniasis in southwest France.

    Directory of Open Access Journals (Sweden)

    Nienke Hartemink

    Full Text Available BACKGROUND: Zoonotic visceral leishmaniasis is endemic in the Mediterranean Basin, where the dog is the main reservoir host. The disease's causative agent, Leishmania infantum, is transmitted by blood-feeding female sandflies. This paper reports an integrative study of canine leishmaniasis in a region of France spanning the southwest Massif Central and the northeast Pyrenees, where the vectors are the sandflies Phlebotomus ariasi and P. perniciosus. METHODS: Sandflies were sampled in 2005 using sticky traps placed uniformly over an area of approximately 100 by 150 km. High- and low-resolution satellite data for the area were combined to construct a model of the sandfly data, which was then used to predict sandfly abundance throughout the area on a pixel by pixel basis (resolution of c. 1 km. Using literature- and expert-derived estimates of other variables and parameters, a spatially explicit R(0 map for leishmaniasis was constructed within a Geographical Information System. R(0 is a measure of the risk of establishment of a disease in an area, and it also correlates with the amount of control needed to stop transmission. CONCLUSIONS: To our knowledge, this is the first analysis that combines a vector abundance prediction model, based on remotely-sensed variables measured at different levels of spatial resolution, with a fully mechanistic process-based temperature-dependent R(0 model. The resulting maps should be considered as proofs-of-principle rather than as ready-to-use risk maps, since validation is currently not possible. The described approach, based on integrating several modeling methods, provides a useful new set of tools for the study of the risk of outbreaks of vector-borne diseases.

  17. Integrated waste management - Looking beyond the solid waste horizon

    International Nuclear Information System (INIS)

    Seadon, J.K.

    2006-01-01

    Waste as a management issue has been evident for over four millennia. Disposal of waste to the biosphere has given way to thinking about, and trying to implement, an integrated waste management approach. In 1996 the United Nations Environmental Programme (UNEP) defined 'integrated waste management' as 'a framework of reference for designing and implementing new waste management systems and for analysing and optimising existing systems'. In this paper the concept of integrated waste management as defined by UNEP is considered, along with the parameters that constitute integrated waste management. The examples used are put into four categories: (1) integration within a single medium (solid, aqueous or atmospheric wastes) by considering alternative waste management options (2) multi-media integration (solid, aqueous, atmospheric and energy wastes) by considering waste management options that can be applied to more than one medium (3) tools (regulatory, economic, voluntary and informational) and (4) agents (governmental bodies (local and national), businesses and the community). This evaluation allows guidelines for enhancing success: (1) as experience increases, it is possible to deal with a greater complexity; and (2) integrated waste management requires a holistic approach, which encompasses a life cycle understanding of products and services. This in turn requires different specialisms to be involved in the instigation and analysis of an integrated waste management system. Taken together these advance the path to sustainability

  18. Integrating research with management: The case of Katavi National ...

    African Journals Online (AJOL)

    Integrating research with management: The case of Katavi National Park, Tanzania. ... national park: (i) reduced water flow caused by local damming of the Katuma River, ... to both management and policy makers for tackling these problems.

  19. Training plan : Dallas Integrated Corridor Management (ICM) demonstration project.

    Science.gov (United States)

    2013-01-01

    The Dallas Area Rapid Transit (DART) is leading the US 75 Integrated Corridor Management (ICM) Demonstration Project for the Dallas region. Coordinated corridor operations and management is predicated on being able to share transportation information...

  20. Test report : Dallas Integrated Corridor Management (ICM) demonstration project.

    Science.gov (United States)

    2015-05-01

    The Dallas Area Rapid Transit (DART) is leading the US 75 Integrated Corridor Management (ICM) : Demonstration Project for the Dallas region. Coordinated corridor operations and management is : predicated on being able to share transportation informa...

  1. Final report : Dallas Integrated Corridor Management (ICM) Demonstration Project.

    Science.gov (United States)

    2015-08-01

    The Dallas Area Rapid Transit (DART) is leading the US-75 Integrated Corridor Management (ICM) Demonstration Project for the Dallas region. Coordinated corridor operations and management is predicated on being able to share transportation information...

  2. Project Management Data Retrieval and Integration (PMDRI) Application

    Data.gov (United States)

    Department of Veterans Affairs — The Project Management Data Retrieval and Integration Database (PMDRI) is a system that presents data from the VA Financial Management System(FMS) in a structured...

  3. Integrated Climate Smart Flood Management for Accra, Ghana ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Home · What we do ... The research team will use evidence to develop an integrated climate smart flood management framework to support policymaking. ... The Ministry of Environment, Science, Technology, and Innovation will manage the ...

  4. INTEGRATED WATERSHED MANAGEMENT: PRINCIPLES AND PRACTICE. Book Review

    Science.gov (United States)

    Through a wide range of information and topics, Integrated Watershed Management Principles and Practice shows how involved the watershed management planning process can be. The book is informative, and the author obviously has researched the subject thoroughly. The book's case...

  5. Integrated solid waste management: a palliative to existing waste ...

    African Journals Online (AJOL)

    As a concept, Integrated Solid Waste Management (ISWM) is a sustainable ... on the perspective of consumers on waste generation, collection and disposal. ... to effective solid waste management in the case study area; non-sorting and ...

  6. Roots Air Management System with Integrated Expander

    Energy Technology Data Exchange (ETDEWEB)

    Stretch, Dale [Eaton Corporation, Menomonee Falls, WI (United States); Wright, Brad [Eaton Corporation, Menomonee Falls, WI (United States); Fortini, Matt [Eaton Corporation, Menomonee Falls, WI (United States); Fink, Neal [Ballard Power Systems, Burnaby, BC (Canada); Ramadan, Bassem [Kettering Univ., Flint, MI (United States); Eybergen, William [Eaton Corporation, Menomonee Falls, WI (United States)

    2016-07-06

    PEM fuel cells remain an emerging technology in the vehicle market with several cost and reliability challenges that must be overcome in order to increase market penetration and acceptance. The DOE has identified the lack of a cost effective, reliable, and efficient air supply system that meets the operational requirements of a pressurized PEM 80kW fuel cell as one of the major technological barriers that must be overcome. This project leveraged Roots positive displacement development advancements and demonstrated an efficient and low cost fuel cell air management system. Eaton built upon its P-Series Roots positive displacement design and shifted the peak efficiency making it ideal for use on an 80kW PEM stack. Advantages to this solution include: • Lower speed of the Roots device eliminates complex air bearings present on other systems. • Broad efficiency map of Roots based systems provides an overall higher drive cycle fuel economy. • Core Roots technology has been developed and validated for other transportation applications. Eaton modified their novel R340 Twin Vortices Series (TVS) Roots-type supercharger for this application. The TVS delivers more power and better fuel economy in a smaller package as compared to other supercharger technologies. By properly matching the helix angle with the rotor’s physical aspect ratio, the supercharger’s peak efficiency can be moved to the operating range where it is most beneficial for the application. The compressor was designed to meet the 90 g/s flow at a pressure ratio of 2.5, similar in design to the P-Series 340. A net shape plastic expander housing with integrated motor and compressor was developed to significantly reduce the cost of the system. This integrated design reduced part count by incorporating an overhung expander and motor rotors into the design such that only four bearings and two shafts were utilized.

  7. Sensitive and long-term monitoring of intracellular microRNAs using a non-integrating cytoplasmic RNA vector.

    Science.gov (United States)

    Sano, Masayuki; Ohtaka, Manami; Iijima, Minoru; Nakasu, Asako; Kato, Yoshio; Nakanishi, Mahito

    2017-10-04

    MicroRNAs (miRNAs) are small noncoding RNAs that modulate gene expression at the post-transcriptional level. Different types of cells express unique sets of miRNAs that can be exploited as potential molecular markers to identify specific cell types. Among the variety of miRNA detection methods, a fluorescence-based imaging system that utilises a fluorescent-reporter gene regulated by a target miRNA offers a major advantage for long-term tracking of the miRNA in living cells. In this study, we developed a novel fluorescence-based miRNA-monitoring system using a non-integrating cytoplasmic RNA vector based on a replication-defective and persistent Sendai virus (SeVdp). Because SeVdp vectors robustly and stably express transgenes, this system enabled sensitive monitoring of miRNAs by fluorescence microscopy. By applying this system for cellular reprogramming, we found that miR-124, but not miR-9, was significantly upregulated during direct neuronal conversion. Additionally, we were able to isolate integration-free human induced pluripotent stem cells by long-term tracking of let-7 expression. Notably, this system was easily expandable to allow detection of multiple miRNAs separately and simultaneously. Our findings provide insight into a powerful tool for evaluating miRNA expression during the cellular reprogramming process and for isolating reprogrammed cells potentially useful for medical applications.

  8. Integration of irradiation with cytoplasmic incompatibility to facilitate a lymphatic filariasis vector elimination approach

    Directory of Open Access Journals (Sweden)

    Dobson Stephen L

    2009-08-01

    Full Text Available Abstract Background Mass drug administration (MDA is the emphasis of an ongoing global lymphatic filariasis (LF elimination program by the World Health Organization, in which the entire 'at risk' human population is treated annually with anti-filarial drugs. However, there is evidence that the MDA strategy may not be equally appropriate in all areas of LF transmission, leading to calls for the augmentation of MDA with anti-vector interventions. One potential augmentative intervention is the elimination of vectors via repeated inundative releases of male mosquitoes made cytoplasmically incompatible via an infection with Wolbachia bacteria. However, with a reduction in the vector population size, there is the risk that an accidental female release would permit the establishment of the incompatible Wolbachia infection type, resulting in population replacement instead of population elimination. To avoid the release of fertile females, we propose the exposure of release individuals to low doses of radiation to sterilize any accidentally released females, reducing the risk of population replacement. Results Aedes polynesiensis pupae of differing ages were irradiated to determine a radiation dose that results in sterility but that does not affect the survival and competitiveness of males. Laboratory assays demonstrate that males irradiated at a female sterilizing dosage of 40 Gy are equally competitive with un-irradiated males. No effect of irradiation on the ability of Wolbachia to affect egg hatch was observed. Conclusion An irradiation dose of 40 Gy is sufficient to cause female sterility, but has no observed negative effect on male fitness. The results support further development of this approach as a preventative measure against accidental population replacement.

  9. Efficient generation of integration-free human induced pluripotent stem cells from keratinocytes by simple transfection of episomal vectors.

    Science.gov (United States)

    Piao, Yulan; Hung, Sandy Shen-Chi; Lim, Shiang Y; Wong, Raymond Ching-Bong; Ko, Minoru S H

    2014-07-01

    Keratinocytes represent an easily accessible cell source for derivation of human induced pluripotent stem (hiPS) cells, reportedly achieving higher reprogramming efficiency than fibroblasts. However, most studies utilized a retroviral or lentiviral method for reprogramming of keratinocytes, which introduces undesirable transgene integrations into the host genome. Moreover, current protocols of generating integration-free hiPS cells from keratinocytes are mostly inefficient. In this paper, we describe a more efficient, simple-to-use, and cost-effective method for generating integration-free hiPS cells from keratinocytes. Our improved method using lipid-mediated transfection achieved a reprogramming efficiency of ∼0.14% on average. Keratinocyte-derived hiPS cells showed no integration of episomal vectors, expressed stem cell-specific markers and possessed potentials to differentiate into all three germ layers by in vitro embryoid body formation as well as in vivo teratoma formation. To our knowledge, this represents the most efficient method to generate integration-free hiPS cells from keratinocytes. ©AlphaMed Press.

  10. Integrated Systems Health Management for Space Exploration

    Science.gov (United States)

    Uckun, Serdar

    2005-01-01

    Integrated Systems Health Management (ISHM) is a system engineering discipline that addresses the design, development, operation, and lifecycle management of components, subsystems, vehicles, and other operational systems with the purpose of maintaining nominal system behavior and function and assuring mission safety and effectiveness under off-nominal conditions. NASA missions are often conducted in extreme, unfamiliar environments of space, using unique experimental spacecraft. In these environments, off-nominal conditions can develop with the potential to rapidly escalate into mission- or life-threatening situations. Further, the high visibility of NASA missions means they are always characterized by extraordinary attention to safety. ISHM is a critical element of risk mitigation, mission safety, and mission assurance for exploration. ISHM enables: In-space maintenance and repair; a) Autonomous (and automated) launch abort and crew escape capability; b) Efficient testing and checkout of ground and flight systems; c) Monitoring and trending of ground and flight system operations and performance; d) Enhanced situational awareness and control for ground personnel and crew; e) Vehicle autonomy (self-sufficiency) in responding to off-nominal conditions during long-duration and distant exploration missions; f) In-space maintenance and repair; and g) Efficient ground processing of reusable systems. ISHM concepts and technologies may be applied to any complex engineered system such as transportation systems, orbital or planetary habitats, observatories, command and control systems, life support systems, safety-critical software, and even the health of flight crews. As an overarching design and operational principle implemented at the system-of-systems level, ISHM holds substantial promise in terms of affordability, safety, reliability, and effectiveness of space exploration missions.

  11. Integrated Water Resources Management: A Global Review

    Science.gov (United States)

    Srinivasan, V.; Cohen, M.; Akudago, J.; Keith, D.; Palaniappan, M.

    2011-12-01

    The diversity of water resources endowments and the societal arrangements to use, manage, and govern water makes defining a single paradigm or lens through which to define, prioritize and evaluate interventions in the water sector particularly challenging. Integrated Water Resources Management (IWRM) emerged as the dominant intervention paradigm for water sector interventions in the early 1990s. Since then, while many successful implementations of IWRM have been demonstrated at the local, basin, national and trans-national scales, IWRM has also been severely criticized by the global water community as "having a dubious record that has never been comprehensively analyzed", "curiously ambiguous", and "ineffective at best and counterproductive at worst". Does IWRM hold together as a coherent paradigm or is it a convenient buzzword to describe a diverse collection of water sector interventions? We analyzed 184 case study summaries of IWRM interventions on the Global Water Partnership (GWP) website. The case studies were assessed to find the nature, scale, objectives and outcomes of IWRM. The analysis does not suggest any coherence in IWRM as a paradigm - but does indicate distinct regional trends in IWRM. First, IWRM was done at very different scales in different regions. In Africa two-thirds of the IWRM interventions involved creating national or transnational organizations. In contrast, in Asia and South America, almost two-thirds were watershed, basin, or local body initiatives. Second, IWRM interventions involved very different types of activities in different regions. In Africa and Europe, IWRM entailed creation of policy documents, basin plans and institution building. In contrast, in Asia and Latin America the interventions were much more likely to entail new technology, infrastructure or watershed measures. In Australia, economic measures, new laws and enforcement mechanisms were more commonly used than anywhere else.

  12. Improve data integration performance by employing metadata management utility

    Energy Technology Data Exchange (ETDEWEB)

    Wei, M.; Sung, A.H. [New Mexico Petroleum Recovery Research Center, Socorro, NM (United States)

    2005-07-01

    This conference paper explored ways of integrating petroleum and exploration data obtained from different sources in order to provide more comprehensive data for various analysis purposes and to improve the integrity and consistency of integrated data. This paper proposes a methodology to enhance oil and gas industry data integration performance by cooperating data management utilities in Microsoft SQL Server database management system (DBMS) for small scale data integration without support of commercial software. By semi-automatically capturing metadata, data sources are investigated in detail, data quality problems are partially cleansed, and the performance of data integration is improved. 20 refs., 7 tabs., 1 fig.

  13. Framework for Infectious Disease Analysis: A comprehensive and integrative multi-modeling approach to disease prediction and management.

    Science.gov (United States)

    Erraguntla, Madhav; Zapletal, Josef; Lawley, Mark

    2017-12-01

    The impact of infectious disease on human populations is a function of many factors including environmental conditions, vector dynamics, transmission mechanics, social and cultural behaviors, and public policy. A comprehensive framework for disease management must fully connect the complete disease lifecycle, including emergence from reservoir populations, zoonotic vector transmission, and impact on human societies. The Framework for Infectious Disease Analysis is a software environment and conceptual architecture for data integration, situational awareness, visualization, prediction, and intervention assessment. Framework for Infectious Disease Analysis automatically collects biosurveillance data using natural language processing, integrates structured and unstructured data from multiple sources, applies advanced machine learning, and uses multi-modeling for analyzing disease dynamics and testing interventions in complex, heterogeneous populations. In the illustrative case studies, natural language processing from social media, news feeds, and websites was used for information extraction, biosurveillance, and situation awareness. Classification machine learning algorithms (support vector machines, random forests, and boosting) were used for disease predictions.

  14. [Application of supply chain integration management of medical consumables].

    Science.gov (United States)

    Zhang, Jian

    2013-07-01

    This paper introduces the background, the content, the information management system of material supply chain integration management and the consumables management process. The system helps to expand the selection of hospital supplies varieties, to reduce consumables management costs, to improve the efficiency of supplies, to ensure supplies safety, reliability and traceability.

  15. Development of integrated analytical data management system

    International Nuclear Information System (INIS)

    Onishi, Koichi; Wachi, Isamu; Hiroki, Toshio

    1986-01-01

    The Analysis Subsection of Technical Service Section, Tokai Reprocessing Plant, Tokai Works, is engaged in analysis activities required for the management of processes and measurements in the plant. Currently, it has been desired to increase the reliability of analytical data and to perform analyses more rapidly to cope with the increasing number of analysis works. To meet this end, on-line data processing has been promoted and advanced analytical equipment has been introduced in order to enhance automization. In the present study, an integrated analytical data mangement system is developed which serves for improvement of reliability of analytical data as well as for rapid retrieval and automatic compilation of these data. Fabrication of a basic model of the system has been nearly completed and test operation has already been started. In selecting hardware to be used, examinations were made on easiness of system extension, Japanese language processing function for improving man-machine interface, large-capacity auxiliary memory system, and data base processing function. The existing analysis works wer reviewed in establishing the basic design of the system. According to this basic design, the system can perform such works as analysis of application slips received from clients as well as recording, sending, filing and retrieval of analysis results. (Nogami, K.)

  16. Integrated construction management technology for power plants

    International Nuclear Information System (INIS)

    Okada, Hisako; Miura, Jun; Nishitani, Yasuhiko

    2003-01-01

    The improvement and rationalization of the plant construction technology has been promoted in order to shorten the construction period, to improve the quality and reliability, and especially to reduce construction costs. With the recent remarkable advances of computer technology, it is necessary to introduce an electronic information technology (IT) into the construction field, and to develop a business process. In such a situation, Hitachi has developed and applied integrated construction support system, which is consistent among design, production and construction. This system has design information and schedule information made electronically as a basic database, and characterizes with project management function based on that information. By introduction of this system, electronic processing of information and reduction of paperwork has enabled high efficiency and standardization of on-site indirect work. Furthermore, by collaboration with the civil company, electrical data exchange has been carried out and developed techniques to improve the interface between mechanical and civil work. High accuracy of construction planning and unification of schedule data have been achieved, and consequently, rework and adjustment at the job site have been greatly reduced. (author)

  17. Immunization with Hexon modified adenoviral vectors integrated with gp83 epitope provides protection against Trypanosoma cruzi infection.

    Directory of Open Access Journals (Sweden)

    Anitra L Farrow

    2014-08-01

    Full Text Available Trypanosoma cruzi is the causative agent of Chagas disease. Chagas disease is an endemic infection that affects over 8 million people throughout Latin America and now has become a global challenge. The current pharmacological treatment of patients is unsuccessful in most cases, highly toxic, and no vaccines are available. The results of inadequate treatment could lead to heart failure resulting in death. Therefore, a vaccine that elicits neutralizing antibodies mediated by cell-mediated immune responses and protection against Chagas disease is necessary.The "antigen capsid-incorporation" strategy is based upon the display of the T. cruzi epitope as an integral component of the adenovirus' capsid rather than an encoded transgene. This strategy is predicted to induce a robust humoral immune response to the presented antigen, similar to the response provoked by native Ad capsid proteins. The antigen chosen was T. cruzi gp83, a ligand that is used by T. cruzi to attach to host cells to initiate infection. The gp83 epitope, recognized by the neutralizing MAb 4A4, along with His6 were incorporated into the Ad serotype 5 (Ad5 vector to generate the vector Ad5-HVR1-gp83-18 (Ad5-gp83. This vector was evaluated by molecular and immunological analyses. Vectors were injected to elicit immune responses against gp83 in mouse models. Our findings indicate that mice immunized with the vector Ad5-gp83 and challenged with a lethal dose of T. cruzi trypomastigotes confer strong immunoprotection with significant reduction in parasitemia levels, increased survival rate and induction of neutralizing antibodies.This data demonstrates that immunization with adenovirus containing capsid-incorporated T. cruzi antigen elicits a significant anti-gp83-specific response in two different mouse models, and protection against T. cruzi infection by eliciting neutralizing antibodies mediated by cell-mediated immune responses, as evidenced by the production of several Ig isotypes

  18. Integrated Data Management Processes Expedite Common Data Management Tasks in Autism Research

    OpenAIRE

    Farach, Frank; Sinanis, Naralys; Hawthorne, Julie; Agnew, Henry; Schantz, Tricia; Jensen, Bill; Rozenblit, Leon

    2013-01-01

    We compare the efficiency of (1) just-in-time data management, in which data are cleaned prior to each analysis, and (2) integrated data management, in which data are centralized, cleaned up front, and made available via a query interface. Integrated data management was associated with faster completion of data management requests.

  19. Integrated, regional approach to risk management of industrial systems

    International Nuclear Information System (INIS)

    Chakraborty, S.

    1992-01-01

    This paper focuses on the following four main issues: (1) necessity for an integrated, regional approach to risk management of industrial systems; (2) principles of risk management; (3) integrated approach and overall methodology; and (4) implementation of risk management strategies on a regional basis. The U.N. Interagency project on risk management for large industrial areas, which is a pioneer type of international initiative for an integrated approach to risk management, is discussed in this context. Another encouraging activity for further development of overall methodologies for risk management is the ongoing project on the risk and safety of technical systems at the Swiss Federal Institute of Technology in Aurich. The concept of integral risk management takes into account multidimensional factors including technical, economic, political, social, and ethical considerations to allow a well-balanced decision-making process

  20. Integrating Medical Supply as Part of the Army's Single Integrated Materiel Manager Concept--Why or why Not?

    National Research Council Canada - National Science Library

    Baxter, Shelia

    1998-01-01

    .... To achieve the goal of seamless logistics integration capabilities, one concept is to establish a Single Integrated Materiel Manager for the Army which envisions integrating all such functions...

  1. Integrated management system: expedience and organizational aspects

    Directory of Open Access Journals (Sweden)

    Trunova Ekaterina Viktorovna

    2011-06-01

    Full Text Available The correctly lined up management system is an important element of intellectual capital of company and promotes growth of its market value. In the article grounded, that realization of strategy is impossible without intercommunication of strategic management and business-process management. Such organizational aspects of administrative activity, as role conception of management, strategic office and process office, are observed.

  2. Law for the Integral Management of Waste No. 8839

    International Nuclear Information System (INIS)

    2010-01-01

    The Law for Integral Waste Management No. 8839 was enacted in Costa Rica in 2010. The purpose of this law has been to regulate the integral management of residues and the efficient use of the resources, through the planning and execution of regulatory actions, operational, financial, administrative, educational, environmental and healthy of monitoring and evaluation [es

  3. Integrated Rural-Urban Water Management for Climate Based ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    There are serious short- and long-term consequences on human health, physical assets, economic ... To work, adaptive climate-proof integrated urban water management must extend throughout the whole catchment, an approach known as integrated water resource management. ... Careers · Contact Us · Site map.

  4. The nexus between integrated natural resources management and integrated water resources management in southern Africa

    Science.gov (United States)

    Twomlow, Stephen; Love, David; Walker, Sue

    The low productivity of smallholder farming systems and enterprises in the drier areas of the developing world can be attributed mainly to the limited resources of farming households and the application of inappropriate skills and practices that can lead to the degradation of the natural resource base. This lack of development, particularly in southern Africa, is of growing concern from both an agricultural and environmental perspective. To address this lack of progress, two development paradigms that improve land and water productivity have evolved, somewhat independently, from different scientific constituencies. One championed by the International Agricultural Research constituency is Integrated Natural Resource Management (INRM), whilst the second championed predominantly by Environmental and Civil Engineering constituencies is Integrated Water Resources Management (IWRM). As a result of similar objectives of working towards the millennium development goals of improved food security and environmental sustainability, there exists a nexus between the constituencies of the two paradigms, particularly in terms of appreciating the lessons learned. In this paper lessons are drawn from past INRM research that may have particular relevance to IWRM scientists as they re-direct their focus from blue water issues to green water issues, and vice-versa. Case studies are drawn from the management of water quality for irrigation, green water productivity and a convergence of INRM and IWRM in the management of gold panning in southern Zimbabwe. One point that is abundantly clear from both constituencies is that ‘one-size-fits-all’ or silver bullet solutions that are generally applicable for the enhancement of blue water management/formal irrigation simply do not exist for the smallholder rainfed systems.

  5. Integrated management system laying a foundation for excellence

    Energy Technology Data Exchange (ETDEWEB)

    Brissette, S.; Vincent, D. [Bruce Power, Tiverton, Ontario (Canada)], E-mail: Derek.VINCENT@brucepower.com

    2009-07-01

    Integration in its simplest form involves seamless coordination between organizational elements such as organization structure, processes, systems and documents. This paper discusses the concept of integration in regards to managed systems and examines practical issues of marrying evolving standards to organizational design and overall governance. Bruce Power's experience in developing its Management System into a more integrated approach is described. Leadership sponsorship of an integrated programmatic approach using a Governance, Oversight, Support and Perform (GOSP) model of accountability framework within the Management System has been a critical success factor in Bruce Power's journey towards achieving operational excellence. (author)

  6. Integrated management system laying a foundation for excellence

    International Nuclear Information System (INIS)

    Brissette, S.; Vincent, D.

    2009-01-01

    Integration in its simplest form involves seamless coordination between organizational elements such as organization structure, processes, systems and documents. This paper discusses the concept of integration in regards to managed systems and examines practical issues of marrying evolving standards to organizational design and overall governance. Bruce Power's experience in developing its Management System into a more integrated approach is described. Leadership sponsorship of an integrated programmatic approach using a Governance, Oversight, Support and Perform (GOSP) model of accountability framework within the Management System has been a critical success factor in Bruce Power's journey towards achieving operational excellence. (author)

  7. Gene transfer to primary corneal epithelial cells with an integrating lentiviral vector

    Directory of Open Access Journals (Sweden)

    Lauro Augusto de Oliveira

    2010-10-01

    Full Text Available PURPOSE: To evaluate the transfer of heterologous genes carrying a Green Fluorescent Protein (GFP reporter cassette to primary corneal epithelial cells ex vivo. METHODS: Freshly enucleated rabbit corneoscleral tissue was used to obtain corneal epithelial cell suspension via enzymatic digestion. Cells were plated at a density of 5×10³ cells/cm² and allowed to grow for 5 days (to 70-80% confluency prior to transduction. Gene transfer was monitored using fluorescence microscopy and fluorescence activated cell sorter (FACS. We evaluated the transduction efficiency (TE over time and the dose-response effect of different lentiviral particles. One set of cells were dual sorted by fluorescence activated cell sorter for green fluorescent protein expression as well as Hoechst dye exclusion to evaluate the transduction of potentially corneal epithelial stem cells (side-population phenotypic cells. RESULTS: Green fluorescent protein expressing lentiviral vectors were able to effectively transduce rabbit primary epithelial cells cultured ex vivo. Live cell imaging post-transduction demonstrated GFP-positive cells with normal epithelial cell morphology and growth. The transduction efficiency over time was higher at the 5th post-transduction day (14.1% and tended to stabilize after the 8th day. The number of transduced cells was dose-dependent, and at the highest lentivirus concentrations approached 7%. When double sorted by fluorescence activated cell sorter to isolate both green fluorescent protein positive and side population cells, transduced side population cells were identified. CONCLUSIONS: Lentiviral vectors can effectively transfer heterologous genes to primary corneal epithelial cells expanded ex vivo. Genes were stably expressed over time, transferred in a dose-dependence fashion, and could be transferred to mature corneal cells as well as presumable putative stem cells.

  8. Basic principles, contents, and benefits of an integrated management system

    International Nuclear Information System (INIS)

    Schwarzin, Juergen

    2010-01-01

    The basic principles and contents of an integrated management system are presented. The report focuses on the benefits and the experience accumulated in using an integrated management system. Integrated management systems are characterized by 2 features in particular: - On the one hand, by a system holistically controlling and describing all processes within a company which are necessary to achieve the company policy and company goals as defined. - On the other hand, it combines in one integrated management system various different aspects (such as quality, environmental protection, and safety) and the resulting requirements. Successful implementation of an integrated management system requires a clear commitment by company management to the integrated management system serving as a management tool. Implementation must be assigned the appropriate importance in the company. It must not be viewed as an instrument preserving 'status quo.' Instead, it must be seen as a tool for long-term improvement of the company. Application of the integrated management system minimizes the probability of occurrence of events, but is not able to reduce it to zero. (orig.)

  9. CANDU plant life management - An integrated approach

    International Nuclear Information System (INIS)

    Charlebois, P.; Hart, R.S.; Hopkins, J.R.

    1998-01-01

    Commercial versions of CANDU reactors were put into service starting more than 25 years ago. The first unit of Ontario Hydro's Pickering A station was put into service in 1971, and Bruce A in 1977. Most CANDU reactors, however, are only now approaching their mid-life of 15 to 20 years of operation. In particular, the first series of CANDU 6 plants which entered service in the early 1980's were designed for a 30 year life and are now approaching mid life. The current CANDU 6 design is based on a 40 year life as a result of advancement in design and materials through research and development. In order to assure safe and economic operation of these reactors, a comprehensive CANDU Plant Life Management (PLIM) program is being developed from the knowledge gained during the operation of Ontario Hydro's Pickering, Bruce, and Darlington stations, worldwide information from CANDU 6 stations, CANDU research and development programs, and other national and international sources. This integration began its first phase in 1994, with the identification of most of the critical systems structures and components in these stations, and a preliminary assessment of degradation and mechanisms that could affect their fitness for service for their planned life. Most of these preliminary assessments are now complete, together with the production of the first iteration of Life Management Plans for several of the systems and components. The Generic CANDU 6 PLIM program is now reaching its maturity, with formal processes to systematically identify and evaluate the major CSSCs in the station, and a plan to ensure that the plant surveillance, operation, and maintenance programs monitor and control component degradation well within the original design specifications essential for the plant life attainment. A Technology Watch program is being established to ensure that degradation mechanisms which could impact on plant life are promptly investigated and mitigating programs established. The

  10. Accumulation of long-term transcriptionally active integrated retroviral vectors in active promoters and enhancers

    Czech Academy of Sciences Publication Activity Database

    Šenigl, Filip; Miklík, Dalibor; Auxt, Miroslav; Hejnar, Jiří

    2017-01-01

    Roč. 45, č. 22 (2017), s. 12752-12765 ISSN 0305-1048 R&D Projects: GA ČR(CZ) GA14-34873S; GA MŠk LO1419 Institutional support: RVO:68378050 Keywords : human-immunodeficiency-virus * dna methylation * site selection * human genome * avian-sarcoma * morphological reversion * hiv-1 integration * mlv integration * gene-expression * leukosis virus Subject RIV: EB - Genetics ; Molecular Biology OBOR OECD: Virology Impact factor: 10.162, year: 2016

  11. IM (Integrity Management) software must show flexibility to local codes

    Energy Technology Data Exchange (ETDEWEB)

    Brors, Markus [ROSEN Technology and Research Center GmbH (Germany); Diggory, Ian [Macaw Engineering Ltd., Northumberland (United Kingdom)

    2009-07-01

    There are many internationally recognized codes and standards, such as API 1160 and ASME B31.8S, which help pipeline operators to manage and maintain the integrity of their pipeline networks. However, operators in many countries still use local codes that often reflect the history of pipeline developments in their region and are based on direct experience and research on their pipelines. As pipeline companies come under increasing regulatory and financial pressures to maintain the integrity of their networks, it is important that operators using regional codes are able to benchmark their integrity management schemes against these international standards. Any comprehensive Pipeline Integrity Management System (PIMS) software package should therefore not only incorporate industry standards for pipeline integrity assessment but also be capable of implementing regional codes for comparison purposes. This paper describes the challenges and benefits of incorporating one such set of regional pipeline standards into ROSEN Asset Integrity Management Software (ROAIMS). (author)

  12. A tough egg to crack: recreational boats as vectors for invasive goby eggs and transdisciplinary management approaches.

    Science.gov (United States)

    Hirsch, Philipp E; Adrian-Kalchhauser, Irene; Flämig, Sylvie; N'Guyen, Anouk; Defila, Rico; Di Giulio, Antonietta; Burkhardt-Holm, Patricia

    2016-02-01

    Non-native invasive species are a major threat to biodiversity, especially in freshwater ecosystems. Freshwater ecosystems are naturally rather isolated from one another. Nonetheless, invasive species often spread rapidly across water sheds. This spread is to a large extent realized by human activities that provide vectors. For example, recreational boats can carry invasive species propagules as "aquatic hitch-hikers" within and across water sheds. We used invasive gobies in Switzerland as a case study to test the plausibility that recreational boats can serve as vectors for invasive fish and that fish eggs can serve as propagules. We found that the peak season of boat movements across Switzerland and the goby spawning season overlap temporally. It is thus plausible that goby eggs attached to boats, anchors, or gear may be transported across watersheds. In experimental trials, we found that goby eggs show resistance to physical removal (90 mN attachment strength of individual eggs) and stay attached if exposed to rapid water flow (2.8 m·s(-1)for 1 h). When exposing the eggs to air, we found that hatching success remained high (>95%) even after eggs had been out of water for up to 24 h. It is thus plausible that eggs survive pick up, within-water and overland transport by boats. We complemented the experimental plausibility tests with a survey on how decision makers from inside and outside academia rate the feasibility of managing recreational boats as vectors. We found consensus that an installation of a preventive boat vector management is considered an effective and urgent measure. This study advances our understanding of the potential of recreational boats to serve as vectors for invasive vertebrate species and demonstrates that preventive management of recreational boats is considered feasible by relevant decision makers inside and outside academia.

  13. SIRSALE: integrated video database management tools

    Science.gov (United States)

    Brunie, Lionel; Favory, Loic; Gelas, J. P.; Lefevre, Laurent; Mostefaoui, Ahmed; Nait-Abdesselam, F.

    2002-07-01

    Video databases became an active field of research during the last decade. The main objective in such systems is to provide users with capabilities to friendly search, access and playback distributed stored video data in the same way as they do for traditional distributed databases. Hence, such systems need to deal with hard issues : (a) video documents generate huge volumes of data and are time sensitive (streams must be delivered at a specific bitrate), (b) contents of video data are very hard to be automatically extracted and need to be humanly annotated. To cope with these issues, many approaches have been proposed in the literature including data models, query languages, video indexing etc. In this paper, we present SIRSALE : a set of video databases management tools that allow users to manipulate video documents and streams stored in large distributed repositories. All the proposed tools are based on generic models that can be customized for specific applications using ad-hoc adaptation modules. More precisely, SIRSALE allows users to : (a) browse video documents by structures (sequences, scenes, shots) and (b) query the video database content by using a graphical tool, adapted to the nature of the target video documents. This paper also presents an annotating interface which allows archivists to describe the content of video documents. All these tools are coupled to a video player integrating remote VCR functionalities and are based on active network technology. So, we present how dedicated active services allow an optimized video transport for video streams (with Tamanoir active nodes). We then describe experiments of using SIRSALE on an archive of news video and soccer matches. The system has been demonstrated to professionals with a positive feedback. Finally, we discuss open issues and present some perspectives.

  14. Space station operations task force. Panel 4 report: Management integration

    Science.gov (United States)

    1987-01-01

    The Management Integration Panel of the Space Station Operations Task Force was chartered to provide a structure and ground rules for integrating the efforts of the other three panels and to address a number of cross cutting issues that affect all areas of space station operations. Issues addressed include operations concept implementation, alternatives development and integration process, strategic policy issues and options, and program management emphasis areas.

  15. Dynamic management of integrated residential energy systems

    Science.gov (United States)

    Muratori, Matteo

    dissertation presents a bottom-up highly resolved model of a generic residential energy eco-system in the United States. The model is able to capture the entire energy footprint of an individual household, to include all appliances, space conditioning systems, in-home charging of plug-in electric vehicles, and any other energy needs, viewing residential and transportation energy needs as an integrated continuum. The residential energy eco-system model is based on a novel bottom-up approach that quantifies consumer energy use behavior. The incorporation of stochastic consumer behaviors allows capturing the electricity consumption of each residential specific end-use, providing an accurate estimation of the actual amount of available controllable resources, and for a better understanding of the potential of residential demand response programs. A dynamic energy management framework is then proposed to manage electricity consumption inside each residential energy eco-system. Objective of the dynamic energy management framework is to optimize the scheduling of all the controllable appliances and in-home charging of plug-in electric vehicles to minimize cost. Such an automated energy management framework is used to simulate residential demand response programs, and evaluate their impact on the electric power infrastructure. For instance, time-varying electricity pricing might lead to synchronization of the individual residential demands, creating pronounced rebound peaks in the aggregate demand that are higher and steeper than the original demand peaks that the time-varying electricity pricing structure intended to eliminate. The modeling tools developed in this study can serve as a virtual laboratory for investigating fundamental economic and policy-related questions regarding the interplay of individual consumers with energy use. The models developed allow for evaluating the impact of different energy policies, technology adoption, and electricity price structures on the total

  16. Managing the resilience space of the German energy system - A vector analysis.

    Science.gov (United States)

    Schlör, Holger; Venghaus, Sandra; Märker, Carolin; Hake, Jürgen-Friedrich

    2018-07-15

    The UN Sustainable Development Goals formulated in 2016 confirmed the sustainability concept of the Earth Summit of 1992 and supported UNEP's green economy transition concept. The transformation of the energy system (Energiewende) is the keystone of Germany's sustainability strategy and of the German green economy concept. We use ten updated energy-related indicators of the German sustainability strategy to analyse the German energy system. The development of the sustainable indicators is examined in the monitoring process by a vector analysis performed in two-dimensional Euclidean space (Euclidean plane). The aim of the novel vector analysis is to measure the current status of the Energiewende in Germany and thereby provide decision makers with information about the strains for the specific remaining pathway of the single indicators and of the total system in order to meet the sustainability targets of the Energiewende. Within this vector model, three vectors (the normative sustainable development vector, the real development vector, and the green economy vector) define the resilience space of our analysis. The resilience space encloses a number of vectors representing different pathways with different technological and socio-economic strains to achieve a sustainable development of the green economy. In this space, the decision will be made as to whether the government measures will lead to a resilient energy system or whether a readjustment of indicator targets or political measures is necessary. The vector analysis enables us to analyse both the government's ambitiousness, which is expressed in the sustainability target for the indicators at the start of the sustainability strategy representing the starting preference order of the German government (SPO) and, secondly, the current preference order of German society in order to bridge the remaining distance to reach the specific sustainability goals of the strategy summarized in the current preference order (CPO

  17. CORPORATIVE MOTIVES ON IMPLEMENTATION OF INTEGRATED MANAGEMENT SYSTEM (IMS

    Directory of Open Access Journals (Sweden)

    Dragan Rajkovic

    2009-09-01

    Full Text Available Integration of management systems for quality, environment, health and risk management as well as corporative social responsibilities is workable corporative approach to reduce costs, effective use of resources, higher motivation of employees and better fulfillment of requirements of social engagements and stakeholders. This paper presents contents of literature and review of a company motives on integrated management system (IMS implementation, namely factors affecting the IMS implementation.

  18. Using remote sensing to inform integrated coastal zone management

    CSIR Research Space (South Africa)

    Roberts, W

    2010-06-01

    Full Text Available TO INFORM INTERGRATED COASTAL ZONE MANAGEMENT GISSA Western Cape Regional Meeting Wesley Roberts & Melanie Luck-Vogel 2 June 2010 CSIR NRE Ecosystems Earth Observation Group What is Integrated Coastal Zone Management? Integrated coastal management... D1D1 B a n d 1 Band 2 Quick theory of CVA Magnitude Direction ( ) ( )22 xaxbyaybM ?+?= Quadrant 1 (++) Accretion Quadrant 2 (-+) Quadrant 4 (+-) Quadrant 3 (--) Erosion CVA Results & Conclusions ? Change in image time series...

  19. Ergonomics Integration Omproving Production Process Management in Enterprises of Latvia

    OpenAIRE

    Henrijs Kaļķis

    2013-01-01

    Dotoral thesis ERGONOMICS INTEGRATION IMPROVING PRODUCTION PROCESS MANAGEMENT IN ENTERPRISES OF LATVIA ANNOTATION Ergonomics integration in process management has great significance in organisations` growth of productivity. It is a new approach to entrepreneurship and business strategy, where ergonomic aspects and values are taken into account in ensuring the effective process management and profitability of enterprises. This study is aimed at solution of the problem of e...

  20. Theoretical framework of integrated strategic performance management system

    OpenAIRE

    Mitrović, Zorica; Todorović, Marija; Bjelica, Dragan

    2015-01-01

    The aim of this paper is to present a conceptual model of the integrated strategic performance management system. This model is conceptual framework designed as a result of research that shows significant benefits of integrated application of strategic management and performance management in organizations. The framework consists of five steps: establishing a planning system, establishing of performance measurement system, establishing an accountability system, establishing of the knowledge m...

  1. Developing Tribal Integrated Waste Management Plans

    Science.gov (United States)

    An IWMP outlines how the tribe will reduce, manage, and dispose of its waste. It identifies existing waste systems, assesses needs, and sets forth the ways to design, implement, and monitor a more effective and sustainable waste management program.

  2. Integrated Facilities Management and Fixed Asset Accounting.

    Science.gov (United States)

    Golz, W. C., Jr.

    1984-01-01

    A record of a school district's assets--land, buildings, machinery, and equipment--can be a useful management tool that meets accounting requirements and provides appropriate information for budgeting, forecasting, and facilities management. (MLF)

  3. Pipeline integrity handbook risk management and evaluation

    CERN Document Server

    Singh, Ramesh

    2013-01-01

    Based on over 40 years of experience in the field, Ramesh Singh goes beyond corrosion control, providing techniques for addressing present and future integrity issues. Pipeline Integrity Handbook provides pipeline engineers with the tools to evaluate and inspect pipelines, safeguard the life cycle of their pipeline asset and ensure that they are optimizing delivery and capability. Presented in easy-to-use, step-by-step order, Pipeline Integrity Handbook is a quick reference for day-to-day use in identifying key pipeline degradation mechanisms and threats to pipeline integrity. The book begins

  4. Testing for co-integration in vector autoregressions with non-stationary volatility

    DEFF Research Database (Denmark)

    Cavaliere, Giuseppe; Rahbek, Anders Christian; Taylor, Robert M.

    2010-01-01

    cases. We show that the conventional rank statistics computed as in (Johansen, 1988) and (Johansen, 1991) are potentially unreliable. In particular, their large sample distributions depend on the integrated covariation of the underlying multivariate volatility process which impacts on both the size...... and power of the associated co-integration tests, as we demonstrate numerically. A solution to the identified inference problem is provided by considering wild bootstrap-based implementations of the rank tests. These do not require the practitioner to specify a parametric model for volatility, or to assume...

  5. Targeted Gene Knock Out Using Nuclease-Assisted Vector Integration: Hemi- and Homozygous Deletion of JAG1.

    Science.gov (United States)

    Gapinske, Michael; Tague, Nathan; Winter, Jackson; Underhill, Gregory H; Perez-Pinera, Pablo

    2018-01-01

    Gene editing technologies are revolutionizing fields such as biomedicine and biotechnology by providing a simple means to manipulate the genetic makeup of essentially any organism. Gene editing tools function by introducing double-stranded breaks at targeted sites within the genome, which the host cells repair preferentially by Non-Homologous End Joining. While the technologies to introduce double-stranded breaks have been extensively optimized, this progress has not been matched by the development of methods to integrate heterologous DNA at the target sites or techniques to detect and isolate cells that harbor the desired modification. We present here a technique for rapid introduction of vectors at target sites in the genome that enables efficient isolation of successfully edited cells.

  6. Research on Integration of NPP Operational Safety Management Performance Systems

    International Nuclear Information System (INIS)

    Chi, Miao; Shi, Liping

    2014-01-01

    The operational safety management of Nuclear Power Plants demands systematic planning and integrated control. NPPs are following the well-developed safety indicator systems proposed by IAEA Operational Safety Performance Indicator Programme, NRC Reactor Oversight Process or the other institutions. Integration of the systems is proposed to benefiting from the advantages of both systems and avoiding improper application into the real world. The authors analyzed the possibility and necessity for system integration, and propose an indicator system integrating method

  7. ESG Integration and the Investment Management Process : Fundamental Investing Reinvented

    NARCIS (Netherlands)

    van Duuren, Emiel; Plantinga, Auke; Scholtens, Bert

    2016-01-01

    We investigate how conventional asset managers account for environmental, social and governance factors (ESG) in their investment process. We do so on the basis of an international survey among fund managers. We find that many conventional managers integrate responsible investing in their investment

  8. Evolution of river management: up to integrated and beyond?

    NARCIS (Netherlands)

    Straatsma, M.W.; Nooij, R.J.W. de

    2010-01-01

    Integrated river management is heralded as the new style of river management, but it has been preceded by a number of previous styles, and is unlikely to be the last. This article presents the first analysis of the evolution of river management using Spiral Dynamics (SD). SD provides a growth

  9. INTEGRATED SAFETY MANAGEMENT SYSTEM IN AIR TRAFFIC SERVICES

    Directory of Open Access Journals (Sweden)

    Volodymyr Kharchenko

    2014-06-01

    Full Text Available The article deals with the analysis of the researches conducted in the field of safety management systems.Safety management system framework, methods and tools for safety analysis in Air Traffic Control have been reviewed.Principles of development of Integrated safety management system in Air Traffic Services have been proposed.

  10. Murine leukemia virus-derived retroviral vector has differential integration patterns in human cell lines used to produce recombinant factor VIII

    Directory of Open Access Journals (Sweden)

    Marcela Cristina Correa de Freitas

    2014-06-01

    Full Text Available OBJECTIVE: Nowadays recombinant factor VIII is produced in murine cells including in Chinese hamster ovary (CHO and baby hamster kidney cells (BHK. Previous studies, using the murine leukemia virus-derived retroviral vector pMFG-FVIII-P140K, modified two recombinant human cell lines, HepG2 and Hek293 to produce recombinant factor VIII. In order to characterize these cells, the present study aimed to analyze the integration pattern of retroviral vector pMFG-FVIII-P140K.METHODS: This study used ligation-mediated polymerase chain reaction to locate the site of viral vector integration by sequencing polymerase chain reaction products. The sequences were compared to genomic databases to characterize respective clones.RESULTS: The retroviral vector presented different and non-random profiles of integration between cells lines. A preference of integration for chromosomes 19, 17 and 11 was observed for HepG2FVIIIdB/P140K and chromosome 9 for Hek293FVIIIdB/P140K. In genomic regions such as CpG islands and transcription factor binding sites, there was no difference in the integration profiles for both cell lines. Integration in intronic regions of encoding protein genes (RefSeq genes was also observed in both cell lines. Twenty percent of integrations occurred at fragile sites in the genome of the HepG2 cell line and 17% in Hek293.CONCLUSION: The results suggest that the cell type can affect the profile of chromosomal integration of the retroviral vector used; these differences may interfere in the level of expression of recombinant proteins.

  11. Total Ore Processing Integration and Management

    Energy Technology Data Exchange (ETDEWEB)

    Leslie Gertsch

    2006-05-15

    This report outlines the technical progress achieved for project DE-FC26-03NT41785 (Total Ore Processing Integration and Management) during the period 01 January through 31 March of 2006. (1) Work in Progress: Minntac Mine--Graphical analysis of drill monitor data moved from two-dimensional horizontal patterns to vertical variations in measured and calculated parameters. The rock quality index and the two dimensionless ({pi}) indices developed by Kewen Yin of the University of Minnesota are used by Minntac Mine to design their blasts, but the drill monitor data from any given pattern is obviously not available for the design of that shot. Therefore, the blast results--which are difficult to quantify in a short time--must be back-analyzed for comparison with the drill monitor data to be useful for subsequent blast designs. {pi}{sub 1} indicates the performance of the drill, while {pi}{sub 2} is a measure of the rock resistance to drilling. As would be expected, since a drill tends to perform better in rock that offers little resistance, {pi}{sub 1} and {pi}{sub 2} are strongly inversely correlated; the relationship is a power function rather than simply linear. Low values of each Pi index tend to be quantized, indicating that these two parameters may be most useful above certain minimum magnitudes. (2) Work in Progress: Hibtac Mine--Statistical examination of a data set from Hibtac Mine (Table 1) shows that incorporating information on the size distribution of material feeding from the crusher to the autogenous mills improves the predictive capability of the model somewhat (43% vs. 44% correlation coefficient), but a more important component is production data from preceding days (26% vs. 44% correlation coefficient), determined using exponentially weighted moving average predictive variables. This lag effect likely reflects the long and varied residence times of the different size fragments in the grinding mills. The rock sizes are also correlated with the geologic

  12. Supply chain integration, risk management and manufacturing flexibility

    DEFF Research Database (Denmark)

    Chaudhuri, Atanu; Boer, Harry; Taran, Yariv

    2018-01-01

    , respectively, and manufacturing flexibility. Design/methodology/approach – Using hierarchical regression, data are analyzed from a sample of 343 manufacturing plants in Asia collected in 2013-2014 as part of the International Manufacturing Strategy Survey (IMSS VI). Findings – Internal integration and supply......Purpose – The purpose of this paper is to investigate the impact of internal integration, external integration and supply chain risk management on manufacturing flexibility, and the moderating effect of supply chain risk management on the relationships between internal and external integration...... chain risk management have a direct effect on manufacturing flexibility. Supply chain risk management moderates the relationship between external integration and flexibility. Research limitations/implications – Further research is needed to generalize beyond the flexibility performance of discrete...

  13. Controlling the vector of distraction osteogenesis in the management of obstructive sleep apnea.

    Science.gov (United States)

    Shilo, Dekel; Emodi, Omri; Aizenbud, Dror; Rachmiel, Adi

    2016-01-01

    Obstructive sleep apnea (OSA) in individuals with craniofacial anomalies can compromise airway and is a serious life-threatening condition. In many cases, tracheostomy is carried out as the treatment of choice. Distraction osteogenesis of the mandible as a treatment modality for OSA is very useful and may spare the need for tracheostomy or allow decannulation, yet controlling the vector of distraction is still a major challenge. We present a method for controlling the vector of distraction. Eight patients with severe respiratory distress secondary to a micrognathic mandible were treated by mandibular distraction osteogenesis using either external or internal devices. Temporary anchorage devices (TADs) and orthodontic elastics were used to control the vector of distraction. Cephalometric X-rays, computed tomography, and polysomnographic sleep studies were used to analyze the results. A mean distraction of 22 mm using the internal devices and a mean of 30 mm using the external devices were achieved. Increase in the pharyngeal airway and hyoid bone advancement was also observed. Anterior-posterior advancement of the mandible was noted with no clockwise rotation. Most importantly, clinical improvement in symptoms of OSA, respiratory distress, and feeding was noted. We describe a method for controlling the vector of distraction used as a treatment for OSA. In these cases, TADs were used as an anchorage unit to control the vector of distraction. Our results show excellent clinical and radiographical results. TADs are a simple and nonexpensive method to control the vector of distraction.

  14. QUANTITATIVE СHARACTERISTICS OF COMPLEMENTARY INTEGRATED HEALTH CARE SYSTEM AND INTEGRATED MEDICATION MANAGEMENT INFORMATION SYSTEM

    Directory of Open Access Journals (Sweden)

    L. Yu. Babintseva

    2015-05-01

    i mportant elements of state regulation of the pharmaceutical sector health. For the first time creation of two information systems: integrated medication management infor mation system and integrated health care system in an integrated medical infor mation area, operating based on th e principle of complementarity was justified. Global and technological coefficients of these systems’ functioning were introduced.

  15. Integrated Space Asset Management Database and Modeling

    Science.gov (United States)

    Gagliano, L.; MacLeod, T.; Mason, S.; Percy, T.; Prescott, J.

    The Space Asset Management Database (SAM-D) was implemented in order to effectively track known objects in space by ingesting information from a variety of databases and performing calculations to determine the expected position of the object at a specified time. While SAM-D performs this task very well, it is limited by technology and is not available outside of the local user base. Modeling and simulation can be powerful tools to exploit the information contained in SAM-D. However, the current system does not allow proper integration options for combining the data with both legacy and new M&S tools. A more capable data management infrastructure would extend SAM-D to support the larger data sets to be generated by the COI. A service-oriented architecture model will allow it to easily expand to incorporate new capabilities, including advanced analytics, M&S tools, fusion techniques and user interface for visualizations. Based on a web-centric approach, the entire COI will be able to access the data and related analytics. In addition, tight control of information sharing policy will increase confidence in the system, which would encourage industry partners to provide commercial data. SIMON is a Government off the Shelf information sharing platform in use throughout DoD and DHS information sharing and situation awareness communities. SIMON providing fine grained control to data owners allowing them to determine exactly how and when their data is shared. SIMON supports a micro-service approach to system development, meaning M&S and analytic services can be easily built or adapted. It is uniquely positioned to fill this need as an information-sharing platform with a proven track record of successful situational awareness system deployments. Combined with the integration of new and legacy M&S tools, a SIMON-based architecture will provide a robust SA environment for the NASA SA COI that can be extended and expanded indefinitely. First Results of Coherent Uplink from a

  16. Efficient data exchange: Integrating a vector GIS with an object-oriented, 3-D visualization system

    International Nuclear Information System (INIS)

    Kuiper, J.; Ayers, A.; Johnson, R.; Tolbert-Smith, M.

    1996-01-01

    A common problem encountered in Geographic Information System (GIS) modeling is the exchange of data between different software packages to best utilize the unique features of each package. This paper describes a project to integrate two systems through efficient data exchange. The first is a widely used GIS based on a relational data model. This system has a broad set of data input, processing, and output capabilities, but lacks three-dimensional (3-D) visualization and certain modeling functions. The second system is a specialized object-oriented package designed for 3-D visualization and modeling. Although this second system is useful for subsurface modeling and hazardous waste site characterization, it does not provide many of the, capabilities of a complete GIS. The system-integration project resulted in an easy-to-use program to transfer information between the systems, making many of the more complex conversion issues transparent to the user. The strengths of both systems are accessible, allowing the scientist more time to focus on analysis. This paper details the capabilities of the two systems, explains the technical issues associated with data exchange and how they were solved, and outlines an example analysis project that used the integrated systems

  17. Integrated Assessment of the Policy of Working Capital Management in Housing and Utilities Enterprises

    Directory of Open Access Journals (Sweden)

    Vladimir Petrovich Poluyanov

    2017-06-01

    Full Text Available The article describes the approaches to the management of current assets in the enterprises of various industries in economic literature. We discuss theoretical, methodological and applied issues concerning the formation and improvement of the working capital management policy in utility companies, which require further study. The authors propose to assess the policy of working capital management in these enterprises by means of the integrated approach based on the system of reasoned indicators defining the type of working capital management policy. It includes indicators characterizing the policy of working capital management, management of the liquidity of working capital and the policy of financing sources management. The indicators which define the type of the policy of working capital management have been chosen as the most influential for each vector of the improvement of management policy. The range of values is set taking into account the current market conditions for the housing and utilities companies based on theoretical standard values adapted to modern situation. The paper proposes to use an integrated indicator for the evaluation of the policy of working capital management in housing and utilities enterprises. We have substantiated the technique of the integrated assessment of the policy of working capital management in housing and utilities companies. As an example of the application of this indicator, we defined the type of the policy of working capital management in Rostovvodokanal Company. The initial data for the calculation of integrated indicators are the official data on the structure of the balance and financial results of Rostovvodokanal Company during the period from 2012 to 2016. At the Rostovvodokanal Company, it is necessary to bring the type of the policy of working capital management and sources of its financing closer to moderate or conservative type. The authors have substantiated the optimal type of policy of

  18. Supply Chain Management and Sustainability: Procrastinating Integration in Mainstream Research

    Directory of Open Access Journals (Sweden)

    Marisa P. de Brito

    2010-03-01

    Full Text Available Research has pointed out opportunities and research agendas to integrate sustainability issues with supply chain and operations management. However, we find that it is still not mainstream practice to systematically take a sustainability approach in tackling supply chain and operations management issues. In this paper, we make use of behavioral theory to explain the current lack of integration. We conclude through abductive reasoning that the reasons for procrastinating integration of sustainability in supply chain and operations management research are the conflicting nature of the task and the inherent context, which is the focus on operations rather than environmental or social issues.

  19. Integrative learning for practicing adaptive resource management

    Directory of Open Access Journals (Sweden)

    Craig A. McLoughlin

    2015-03-01

    Full Text Available Adaptive resource management is a learning-by-doing approach to natural resource management. Its effective practice involves the activation, completion, and regeneration of the "adaptive management cycle" while working toward achieving a flexible set of collaboratively identified objectives. This iterative process requires application of single-, double-, and triple-loop learning, to strategically modify inputs, outputs, assumptions, and hypotheses linked to improving policies, management strategies, and actions, along with transforming governance. Obtaining an appropriate balance between these three modes of learning has been difficult to achieve in practice and building capacity in this area can be achieved through an emphasis on reflexive learning, by employing adaptive feedback systems. A heuristic reflexive learning framework for adaptive resource management is presented in this manuscript. It is built on the conceptual pillars of the following: stakeholder driven adaptive feedback systems; strategic adaptive management (SAM; and hierarchy theory. The SAM Reflexive Learning Framework (SRLF emphasizes the types, roles, and transfer of information within a reflexive learning context. Its adaptive feedback systems enhance the facilitation of single-, double-, and triple-loop learning. Focus on the reflexive learning process is further fostered by streamlining objectives within and across all governance levels; incorporating multiple interlinked adaptive management cycles; having learning as an ongoing, nested process; recognizing when and where to employ the three-modes of learning; distinguishing initiating conditions for this learning; and contemplating practitioner mandates for this learning across governance levels. The SRLF is a key enabler for implementing the "adaptive management cycle," and thereby translating the theory of adaptive resource management into practice. It promotes the heuristics of adaptive management within a cohesive

  20. Site-specific integration of CAR gene into Jurkat T cells with a linear close-ended AAV-based DNA vector for CAR-T engineering.

    Science.gov (United States)

    Zhang, Yun; Liu, Xiaomei; Zhang, Jinju; Zhang, Chun

    2016-09-01

    To develop a site-specific integration strategy for CAR-T engineering by using a non-viral vector dependent on adeno-associated viral (AAV) genome, which tends to be integrated into AAVS1 site with the help of its Rep proteins. AAV-dependent vectors were produced in Sf9 cells. Structural analyses revealed the vector as covalently close-ended, linear duplex molecules, which was termed "CELiD" DNA. A plasmid CMV-Rep was constructed to express the integrases Rep78 and Rep68. Jurkat cells were co-electroporated with "CELiD" DNA and plasmid CMV-Rep in order to specifically integrate CAR gene into AAVS1 site. We examined 71 stably transfected Jurkat clones by nested PCR, sequencing and southern blotting, of which 30 clones bore CAR gene within AAVS1 site. The site-specific integration efficiency was nearly 42.2 %. The AAV-dependent vector preferentially integrated CAR into AAVS1 site, which could be further used in human T cell modification and enhance the security of CAR-T therapy.

  1. Managing Quadrennial Defense Review Integration: An Overview

    National Research Council Canada - National Science Library

    Schrader, John

    2001-01-01

    ...). The lessons learned from the 1997 Quadrennial Defense Review (QDR 1997) included the need for leadership guidance and integration of analytic activities to sort through the myriad issues that are always confronting the Department of Defense...

  2. Armenia : Towards Integrated Water Resources Management

    OpenAIRE

    World Bank

    2001-01-01

    The objective of this paper is to examine the challenges in the water sector faced by Armenia today, and outline options for management and allocation of its water resources in the future, considering the need for a stable, transparent apublic sector management framework and sustainable resource use for long-term private investment and job creation, and for appropriate balances among water...

  3. An integrated approach to plant life management

    International Nuclear Information System (INIS)

    Fredlund, L.

    1998-01-01

    Plant life is no longer determined by components, almost everything can be replaced. A plant life management program should aim at actions and replacements being performed at the right time. In order to manage this there is need for experience feedback systems, a plant specific risk study and safety upgrades. (author)

  4. Pesticides and public health: integrated methods of mosquito management.

    OpenAIRE

    Rose, R. I.

    2001-01-01

    Pesticides have a role in public health as part of sustainable integrated mosquito management. Other components of such management include surveillance, source reduction or prevention, biological control, repellents, traps, and pesticide-resistance management. We assess the future use of mosquito control pesticides in view of niche markets, incentives for new product development, Environmental Protection Agency registration, the Food Quality Protection Act, and improved pest management strate...

  5. Competitiveness in organizational integrated computer system project management

    Directory of Open Access Journals (Sweden)

    Zenovic GHERASIM

    2010-06-01

    Full Text Available The organizational integrated computer system project management aims at achieving competitiveness by unitary, connected and personalised treatment of the requirements for this type of projects, along with the adequate application of all the basic management, administration and project planning principles, as well as of the basic concepts of the organisational information management development. The paper presents some aspects of organizational computer systems project management competitiveness with the specific reference to some Romanian companies’ projects.

  6. Integrated Management System Incorporating Quality Management and Management of Environment, Health and Occupational Safety

    International Nuclear Information System (INIS)

    Manchev, B.; Nenkova, B.; Tomov, E.

    2012-01-01

    Risk Engineering Ltd is a Bulgarian private company founded in 1990 to provide engineering and consulting services applicable to each and every field of the energy sector. Since its establishment Risk Engineering Ltd develops, implement and apply a System for quality assurance, certified for the first time by BVQI (now Bureau Veritas Certification) in 1999 for conformity with the standard ISO 9001:1994. Later on, in connection with the revision of the standards of ISO 9000 series and introduction of the standard ISO 9001:2000 a Quality Management System in conformity with the standard ISO 9001:2000 was developed, introduced and certified. At present, Risk Engineering Ltd has got developed, documented, introduced and certified by Lloyd's Register Quality Assurance (LRQA) Quality Management System in compliance with ISO 9001:2008 on the process approach basis. On this basis and including the requirements of the ISO 14001:2004 (regarding the environment) and OHSAS 18001:2007 (regarding the health and occupational safety), Risk Engineering Ltd has developed and introduced Integrated Management System aim at achieving and demonstrating good results regarding protection of the environment, health and occupational safety. The processes under control by the Integrated Management System and applicable at the company are divided in two general types: A) Management processes: Strategic management and Management of the human resources. B) Processes describing the main activities: design/development process; project management; management of industrial projects and technical infrastructure project; construction, installation, repair and operation of power industry facilities; commercial activities and marketing; investigation of energy efficiency of industrial systems and certification of buildings regarding energy efficiency; consulting activity in the field of industry and energy as well as consultant in accordance with the Law of the Spatial Planning; management of the

  7. The Identification of Hunger Behaviour of Lates Calcarifer through the Integration of Image Processing Technique and Support Vector Machine

    Science.gov (United States)

    Taha, Z.; Razman, M. A. M.; Adnan, F. A.; Ghani, A. S. Abdul; Majeed, A. P. P. Abdul; Musa, R. M.; Sallehudin, M. F.; Mukai, Y.

    2018-03-01

    Fish Hunger behaviour is one of the important element in determining the fish feeding routine, especially for farmed fishes. Inaccurate feeding routines (under-feeding or over-feeding) lead the fishes to die and thus, reduces the total production of fishes. The excessive food which is not eaten by fish will be dissolved in the water and thus, reduce the water quality (oxygen quantity in the water will be reduced). The reduction of oxygen (water quality) leads the fish to die and in some cases, may lead to fish diseases. This study correlates Barramundi fish-school behaviour with hunger condition through the hybrid data integration of image processing technique. The behaviour is clustered with respect to the position of the centre of gravity of the school of fish prior feeding, during feeding and after feeding. The clustered fish behaviour is then classified by means of a machine learning technique namely Support vector machine (SVM). It has been shown from the study that the Fine Gaussian variation of SVM is able to provide a reasonably accurate classification of fish feeding behaviour with a classification accuracy of 79.7%. The proposed integration technique may increase the usefulness of the captured data and thus better differentiates the various behaviour of farmed fishes.

  8. Multidimensionality evaluation of supply chain management integration

    Directory of Open Access Journals (Sweden)

    Fernanda Paes Arantes

    2018-03-01

    Full Text Available Integration is constantly reported in the literature as an essential feature of SCM. However, it is as difficult to define as to operationalize it, resulting in a lack of information on how to increase the level of integration among members. Thus, this research aims to evaluate the dimensionality of SCI, to check alignment with the features identified in the literature using multivariate statistical analysis. The methodology used was based on a questionnaire to assess the level of companies integration with suppliers of its supply chain. This instrument consisted of 21 items, with response options: yes, no or not applicable. The questions focused on evaluating the integration with suppliers, so each company consulted could answer a questionnaire for each supplier, since the intensity of relationships varies. Thus, 41 companies participated in the survey, resulting in 205 responses. Full-information item factor analysis and principal component analysis on the correlation matrix tetrachoric were used for the instrument dimensionality analysis. They are appropriate procedures for analysis of dichotomous variables. The results of this analysis enabled grouping the questionnaire items in the following underlying factors: trust, information sharing, partnership, collaboration or cooperation, and coordination. The identification of such factors such as dimensions of SCI enables greater understanding on how to raise the level of integration among the members of a supply chain.

  9. Assessment and management of ecological integrity: Chapter 12

    Science.gov (United States)

    Kwak, Thomas J.; Freeman, Mary C.

    2010-01-01

    Assessing and understanding the impacts of human activities on aquatic ecosystems has long been a focus of ecologists, water resources managers, and fisheries scientists. While traditional fisheries management focused on single-species approaches to enhance fish stocks, there is a growing emphasis on management approaches at community and ecosystem levels. Of course, as fisheries managers shift their attention from narrow (e.g., populations) to broad organizational scales (e.g., communities or ecosystems), ecological processes and management objectives become more complex. At the community level, fisheries managers may strive for a fish assemblage that is complex, persistent, and resilient to disturbance. Aquatic ecosystem level objectives may focus on management for habitat quality and ecological processes, such as nutrient dynamics, productivity, or trophic interactions, but a long-term goal of ecosystem management may be to maintain ecological integrity. However, human users and social, economic, and political demands of fisheries management often result in a reduction of ecological integrity in managed systems, and this conflict presents a principal challenge for the modern fisheries manager. The concepts of biotic integrity and ecological integrity are being applied in fisheries science, natural resource management, and environmental legislation, but explicit definitions of these terms are elusive. Biotic integrity of an ecosystem may be defined as the capability of supporting and maintaining an integrated, adaptive community of organisms having a species composition, diversity, and functional organization comparable to that of a natural habitat of the region (Karr and Dudley 1981). Following that, ecological integrity is the summation of chemical, physical, and biological integrity. Thus, the concept of ecological integrity extends beyond fish and represents a holistic approach for ecosystem management that is especially applicable to aquatic systems. The

  10. Integration and change management for successful mergers; Integration und Change Management bei Fusionen

    Energy Technology Data Exchange (ETDEWEB)

    Wolf, H.G. [Arthur Andersen Business Consulting GmbH, Duesseldorf (Germany)

    2000-05-01

    In the wake of deregulation of the energy markets in Germany, energy companies and electric utilities are confronted with fierce competition on prices and customers. The change of paradigms in the German energy industry calls for new strategies. The article discusses strategic alliances and mergers as one way to cope with the challenges, and explains suitable and proven approaches for corporate integration and change management. (CB) [German] Seit der wettbewerblichen Oeffnung des deutschen Energiemarktes sehen sich die Unternehmen mit einem dramatischen Preis- und Marketingwettbewerb konfrontiert. Aggressive neue Akteure draengen in die lukrativen Maerkte. Aber auch etablierte Teilnehmer suchen neue strategische Positionen und beschleunigen den Paradigmenwechsel in der deutschen Energiewirtschaft. Angesichts dieser Marktentwicklung bestehen massive Anforderungen zur Veraenderung. Unternehmenszusammenschluesse und Kooperationen stellen eine geeignete strategische Reaktion zur Bewaeltigung dieser Herausforderungen dar. Dabei sollten die Risiken von Fusionen nicht unterschaetzt werden. Die meisten Vorhaben scheitern auf Grund fehlender Integrationsprozesse. Ein systematischer Integrationsansatz wird beschrieben. (orig./CB)

  11. Innovation Management in Emerging Technology Ventures – The Concept of an Integrated Idea Management

    DEFF Research Database (Denmark)

    Brem, Alexander; Voigt, K.-I.

    2007-01-01

    , development and sales. Here especially, differentiating potentials are offered for emerging technology ventures. But it is important that idea and innovation management are integrated during the building-up stage while internal and external network structures are still manageable and often consist...... of the managers' and founders' personal contacts. Hence, the earlier an integrated idea management is implemented, the greater is the probability of high numbers of successful innovations.......For decades, suggestion systems have been used to include employees in the innovation process. However, in order to gather superior ideas, integrating external stakeholders is critical to the innovation success. Within this paper, the authors derive a sophisticated model of an integrated idea...

  12. Research on monitoring and management information integration technique in waste treatment and management

    International Nuclear Information System (INIS)

    Kong Jinsong; Yu Ren; Mao Wei

    2013-01-01

    The integration of the waste treatment process and the device status monitoring information and management information is a key problem required to be solved in the information integration of the waste treatment and management. The main content of the monitoring and management information integration is discussed in the paper. The data exchange techniques, which are based on the OPC, FTP and data push technology, are applied to the different monitoring system respectively, according to their development platform, to realize the integration of the waste treatment process and device status monitoring information and management information in a waste treatment center. (authors)

  13. promoting integrated water resources management in south west

    African Journals Online (AJOL)

    eobe

    1, 2 SOUTH WEST REGIONAL CENTRE FOR NATIONAL WATER RESOURCES CAPACITY BUILDING NETWORK,. FEDERAL UNIVERSITY OF ... that an integrated approach to water resource development and management offers the best ...

  14. Evaluation of pre-service training on integrated management of ...

    African Journals Online (AJOL)

    Evaluation of pre-service training on integrated management of neonatal and childhood ... and reviews of pediatric course outlines and other teaching/learning materials. ... Of the 34 programs 22 were diploma nursing, 6 Bachelor of Sciences ...

  15. Integrated Measurement of Crew Resource Management and Technical Flying Skills

    Science.gov (United States)

    1993-08-01

    This report presents the findings of a study designed with two objectives: to produce a prototype performance : measurement instrument (PMI) that integrates the assessment of Crew Resource Management (CRM) and technical flying : skills and to investi...

  16. Integrated management of root-knot nematode (Meloidogyne ...

    African Journals Online (AJOL)

    Integrated management of root-knot nematode (Meloidogyne incognita) for tomato production and productivity. Bayuh Belay1* ... important food and cash crop of the farmers and is ...... some part of the research budget without any reservation.

  17. Adoption of Integrated Pest Management among Cocoa Farmers in ...

    African Journals Online (AJOL)

    E M IGBOKWE

    Keywords: Integrated pest management, Cocoa farmers, Farmers Field School ... Total World production has increased in absolute terms from 3.98 million metric ..... and G.C. Rausser, eds Handbook of Agricultural Economics, Vol. 1B,.

  18. Integrating distributed Bayesian inference and reinforcement learning for sensor management

    NARCIS (Netherlands)

    Grappiolo, C.; Whiteson, S.; Pavlin, G.; Bakker, B.

    2009-01-01

    This paper introduces a sensor management approach that integrates distributed Bayesian inference (DBI) and reinforcement learning (RL). DBI is implemented using distributed perception networks (DPNs), a multiagent approach to performing efficient inference, while RL is used to automatically

  19. Some aspects of integrated coastal zone management in India

    Digital Repository Service at National Institute of Oceanography (India)

    Untawale, A.G.

    . This trend has created tremendous pressures and the ecological balance is disturbing. There are various factors which are degrading the coastal waters. The Integrated Coastal Management is relatively a recent concept, which involves multidisciplinary approach...

  20. Sensor Area Network for Integrated Systems Health Management, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — The term Integrated Systems Health Management (ISHM) is used to describe a capability that focuses on determining the condition of every element in a complex System...

  1. Integration of structural health monitoring and asset management.

    Science.gov (United States)

    2012-08-01

    This project investigated the feasibility and potential benefits of the integration of infrastructure monitoring systems into enterprise-scale transportation management systems. An infrastructure monitoring system designed for bridges was implemented...

  2. Chip Integrated, Hybrid EHD/Capillary Driven Thermal Management System

    Data.gov (United States)

    National Aeronautics and Space Administration — Chip-Integrated, Hybrid EHD/Capillary-Driven Thermal Management System is a two year that will leverage independently attained yet related prototype hardware...

  3. In-flight Integrated Mission Management System (I-LIMMS)

    National Research Council Canada - National Science Library

    Emmitt, George D; Greco, Steven; Wood, Sidney

    2006-01-01

    The goal of this Phase I SBIR effort was to determine the feasibility and preliminary design of I-LIMMS, an In-flight Lidar Integrated Mission Management System for the processing and visualization...

  4. Sensor Area Network for Integrated Systems Health Management, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — The term Integrated Systems Health Management (ISHM) is used to describe a capability that focuses on determining the condition (health) of every element in a...

  5. Privacy Impact Assessment for the Integrated Grants Management System

    Science.gov (United States)

    The Integrated Management System collects contact information and other Personally Identifiable Information (PII). Learn how this data is collected, how it will be used, access to the data, the purpose of data collection, and record retention policies.

  6. Privacy Impact Assessment for the Integrated Contracts Management System

    Science.gov (United States)

    The Integrated Contracts Management System collects contact information and other Personally Identifiable Information (PII). Learn how this data will be collected in the system, how it will be used, access to the data, and the purpose of data collection.

  7. Integrated corridor management : implementation guide and lessons learned.

    Science.gov (United States)

    2012-02-01

    This implementation guide is intended for use by adopters of integrated corridor management (ICM) approaches and strategies to address congestion and travel time reliability issues within specific travel corridors. It introduces the topic of ICM and ...

  8. Development and improvement of the integrated system of management

    Directory of Open Access Journals (Sweden)

    Lukmanova Inessa Galeevna

    2014-07-01

    Full Text Available Integrated management system construction can be considered a way that transforms using business processes and information resources into final construction products. Autonomous system of quality management, environmental, health and safety organizations introduction usually lead to the accumulation of duplicate documents, which increase the time spent on processing and analysis as well as increase the financial costs of maintaining the operation of each of them separately. System integration allows reducing these costs and entailing the most obvious benefits: reduced volumes of documents; reduction of time spent on analysis; reducing the cost of audit and certification; involvement of all the employees of the organization; productivity growth; increasing the attractiveness for consumers; reducing the burden on administrative and executive devices; ensuring a high level of flexibility in the organization's management system in case of internal and external changes. Integration of quality management systems, environmental management and safety management systems, production and safety led to the possibility to establish such integrated management system in developing building companies, which allows establishing a unified management system, as an element of management of organization. The main drawback of the currently used standards and specifications is the lack of flexibility of their application, as well as the basic principles and approaches to their implementation. Thus, knowing about what the system should be, but not knowing how to create it, many organizations have to operate without methodological support. Absence of mandatory standards concerning integration of management systems creates opportunities for the existence of multiple options for interaction systems. Economic effects on the integrated management system is formed from three sources: the reduction of production costs by improving product quality and reducing defects and

  9. Integrated Structural Health Management, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Cornerstone Research Group Inc. (CRG) proposes to advance the state of the art in composite health management through refinement of an existing technology developed...

  10. Integrated sign management system : ADOT maintenance group

    Science.gov (United States)

    2003-12-01

    The Arizona Department of Transportation (ADOT) maintains and manages an inventory of roadway signs. Before the implementation of this project, sign technicians maintained inventory records on individual laptops to track their daily sign maintenance ...

  11. The integration of environmental management standards in ...

    African Journals Online (AJOL)

    Research in Hospitality Management is co-published by NISC (Pty) Ltd and Routledge, .... over a total of 12 categories that can all fit the concept of ... Purchasing strategies and reducing consumption ..... In this case there are three options: 1.

  12. Risk management integration into complex project organizations

    Science.gov (United States)

    Fisher, K.; Greanias, G.; Rose, J.; Dumas, R.

    2002-01-01

    This paper describes the approach used in designing and adapting the SIRTF prototype, discusses some of the lessons learned in developing the SIRTF prototype, and explains the adaptability of the risk management database to varying levels project complexity.

  13. Integrated Vegetation Management Practices Memorandum of Understanding

    Science.gov (United States)

    Memorandum of Understanding between EPA and the Edison Electric Institute, U.S. Department of Agriculture (Forest Service), and U.S. Department of the Interior (Bureau of Land Management, Fish and Wildlife Service, and National Park Service for IVM.

  14. Smallholder integrated crop management (ICM) research planning ...

    African Journals Online (AJOL)

    Mo

    More women farmers were invited because they do most of the farming. Other participants came from ... smallholders to innovate their land and crop management strategies. This would be ..... Asian Farming Systems Association, 2 (2): 67.

  15. An integration architecture for knowledge management system and business process management system

    NARCIS (Netherlands)

    Jung, J.; Choi, I.; Song, M.S.

    2007-01-01

    Recently, interests in the notion of process-oriented knowledge management (PKM) from academia and industry have been significantly increased. Comprehensive research and development requirements along with a cogent framework, however, have not been proposed for integrating knowledge management (KM)

  16. Management systems for high reliability organizations. Integration and effectiveness; Managementsysteme fuer Hochzuverlaessigkeitsorganisationen. Integration und Wirksamkeit

    Energy Technology Data Exchange (ETDEWEB)

    Mayer, Michael

    2015-03-09

    The scope of the thesis is the development of a method for improvement of efficient integrated management systems for high reliability organizations (HRO). A comprehensive analysis of severe accident prevention is performed. Severe accident management, mitigation measures and business continuity management are not included. High reliability organizations are complex and potentially dynamic organization forms that can be inherently dangerous like nuclear power plants, offshore platforms, chemical facilities, large ships or large aircrafts. A recursive generic management system model (RGM) was development based on the following factors: systemic and cybernetic Asepcts; integration of different management fields, high decision quality, integration of efficient methods of safety and risk analysis, integration of human reliability aspects, effectiveness evaluation and improvement.

  17. Contribution to the center and integrability problems in planar vector fields

    OpenAIRE

    Santallusia Esvert, Xavier

    2017-01-01

    Aquesta tesi consta d'un primer capítol introductori, set capítols amb diferents resultats i una bibliografia. El primer capítol conté la definició i els resultats previs necessaris per abordar la resta de la memòria. El capítol 2 i 3 estan molt relacionats. En el primer es descriu un mètode alternatiu per al còmput de les constants de Poincaré--Liapunov. A diferència de mètodes anteriors, el mètode presentat no requereix el càlcul d'integrals i d'ona de forma explícita les constants de P...

  18. Structural Integrity Management for Fixed Offshore Platforms in Malaysia

    OpenAIRE

    Narayanan Sambu Potty; Mohammad Kabir B. Mohd Akram

    2009-01-01

    Structural Integrity Management (SIM) is important for the protection of offshore crew, environment, business assets and company and industry reputation. API RP 2A contained guidelines for assessment of existing platforms mostly for the Gulf of Mexico (GOM). ISO 19902 SIM framework also does not specifically cater for Malaysia. There are about 200 platforms in Malaysia with 90 exceeding their design life. The Petronas Carigali Sdn Bhd (PCSB) uses the Asset Integrity Management ...

  19. Groundwater/Vadose Zone Integration Project Management Plan

    International Nuclear Information System (INIS)

    Hughes, M. C.

    1999-01-01

    This Project Management Plan (PMP) defines the authorities, roles, and responsibilities of the US Department of Energy (DOE), Richland Operations Office (RL) and those contractor organizations participating in the Hanford Site' s Groundwater/Vadose Zone (GW/VZ) Integration Project. The PMP also describes the planning and control systems, business processes, and other management tools needed to properly and consistently conduct the Integration Project scope of work

  20. Integrated management systems: survey results from Portuguese companies and experts

    OpenAIRE

    Domingues, Pedro; Sampaio, Paulo; Arezes, P.

    2012-01-01

    The proliferation of several certifiable sub-systems among different type of organizations lead companies to excessive departmentalization. This fact turned out to be, due to several reasons pointed out by numerous authors, disadvantageous. Hence, organizations optioned by integration of their management sub-systems. Academic awareness to this sociological event is mainly related with the fact of integration of management systems (IMS) had been performed empirically, that is, by each organiza...

  1. The tortoise shell Integrated Coastal Management in Galapagos

    OpenAIRE

    Polit Arguello, Victor Manuel

    2013-01-01

    The current work aims to examine the legal framework for Integrated Coastal Management for Archipelago de Galapagos. It examines the content of ICM at the internal level in order to find if there is a standard for appropriate Integrated Management of Coastal Zones. Also it aims to define whether the ratification of UNCLOS by the government of Ecuador should affect the implementation of such framework.

  2. Understanding Organizational Memory from the Integrated Management Systems (ERP)

    OpenAIRE

    Gilberto Perez; Isabel Ramos

    2013-01-01

    With this research, in the form of a theoretical essay addressing the theme of Organizational Memory and Integrated Management Systems (ERP), we tried to present some evidence of how this type of system can contribute to the consolidation of certain features of Organizational Memory. From a theoretical review of the concepts of Human Memory, extending to the Organizational Memory and Information Systems, with emphasis on Integrated Management Systems (ERP) we tried to draw a parallel between ...

  3. DESIGN OF INFORMATION MANAGEMENT SYSTEM OF VERTICALLY INTEGRATED AGRICULTURAL HOLDINGS

    Directory of Open Access Journals (Sweden)

    Александр Витальевич ШМАТКО

    2015-05-01

    Full Text Available The paper deals with an approach to the design and development of information systems for the management and optimization of the organizational structure of vertically integrated agricultural holdings. A review of the problems of building and improving the organizational structure of vertically integrated agricultural holding is made. A method of constructing a discrete model management structure agricultural holding, which minimizes the costs associated with attracting applicants to work, is proposed.

  4. Integrated management system: The integration of ISO 9001, ISO 14001, OHSAS 18001 and ISO 31000

    Science.gov (United States)

    Muzaimi, Hafizzudin; Chew, Boon Cheong; Hamid, Syaiful Rizal

    2017-03-01

    The implementation of integrated management system (IMS) for better quality management has become a preference for many organizations. This can be seen as many organizations used the combination of quality ISO 9001, an environment ISO 14001 and occupational health and safety management system OHSAS 18001 as a core for the IMS that largely implemented. Besides, the linked between quality management with risk management system need to be identified as the management system that enhance the effectiveness of IMS. Therefore, the risk management system ISO 31000 also presented as a part of integration. In nowadays competitive environment, the increasing pressure and needs from customer or stakeholders make it compulsory for the organization to propose the new system and standards. This paper presents and discusses about the benefit of integration, the management system components that can be converged and the implementation approach. A series of interview was conducted through in-depth interviews with 8 experts in this field, while data collected were analyzed qualitatively. The results consist of 16 factors of IMS implementation that have been identified and the use of PDCA approach for an effective implementation of IMS. As a conclusion, the paper proposes the integration of four management systems (ISO 9001, ISO 14001, OHSAS 18001 and ISO 31000) and on how the IMS can be used to structure the process of management for quality management towards sustainability practices in the organization.

  5. Maintaining control while delegating trust: Integrity constraints in trust management

    NARCIS (Netherlands)

    Etalle, S.; Winsborough, W.H.

    2009-01-01

    We introduce the use, monitoring, and enforcement of integrity constraints in trust management-style authorization systems. We consider what portions of the policy state must be monitored to detect violations of integrity constraints. Then, we address the fact that not all participants in a

  6. Integrated Pest Management of the Southern Pine Beetle

    Science.gov (United States)

    Robert N. Coulson; Hannu Saarenmaa

    2011-01-01

    Integrated pest management (IPM) is the maintenance of destructive agents, including insects, at tolerable levels by the planned use of a variety of preventive, suppressive, or regulatory tactics and strategies that are ecologically and economically efficient and socially and politically acceptable. It is explicit that the actions taken are fully integrated into the...

  7. Implementing Integrated Multicultural Instructional Design in Management Education

    Science.gov (United States)

    Schultz, Jennifer L.; Higbee, Jeanne L.

    2011-01-01

    This purpose of this paper is to summarize the principles of integrated multicultural instructional design (IMID; Higbee, Goff, & Schultz, in press; Higbee, Schultz, & Goff, 2010) and present specific strategies for incorporating IMID in management education. The primary goal of IMID is to promote the integration of multicultural content…

  8. Integrating Social Science and Ecosystem Management: A National Challenge

    Science.gov (United States)

    Cordell; H. Ken; Linda Caldwell

    1995-01-01

    These proceedings contain the contributed papers and panel presentations, as well as a paper presented at the National Workshop, of the Conference on Integrating Social Sciences and Ecosystem Management, which was held at Unicoi Lodge and Conference Center, Helen, GA, December 12-14, 1995. The overall purpose of this Conference was to improve understanding, integration...

  9. Integrating an Information Literacy Quiz into the Learning Management System

    Science.gov (United States)

    Lowe, M. Sara; Booth, Char; Tagge, Natalie; Stone, Sean

    2014-01-01

    The Claremont Colleges Library Instruction Services Department developed a quiz that could be integrated into the consortial learning management software to accompany a local online, open-source information literacy tutorial. The quiz is integrated into individual course pages, allowing students to receive a grade for completion and improving…

  10. Management Ethics: Integrity at Work. Sage Series on Business Ethics.

    Science.gov (United States)

    Petrick, Joseph A.; Quinn, John F.

    This book tries to redefine what it means for a manager to function with integrity and competence in the private and public sectors domestically and globally. It integrates theoretical work in both descriptive and normative ethics and incorporates legal, communication, quality, and organizational theories into a conceptual framework designed to…

  11. Risk assessments for exposure of deployed military personnel to insecticides and personal protective measures used for disease-vector management.

    Science.gov (United States)

    Macedo, Paula A; Peterson, Robert K D; Davis, Ryan S

    2007-10-01

    Infectious diseases are problematic for deployed military forces throughout the world, and, historically, more military service days have been lost to insect-vectored diseases than to combat. Because of the limitations in efficacy and availability of both vaccines and therapeutic drugs, vector management often is the best tool that military personnel have against most vector-borne pathogens. However, the use of insecticides may raise concerns about the safety of their effects on the health of the military personnel exposed to them. Therefore, our objective was to use risk assessment methodologies to evaluate health risks to deployed U.S. military personnel from vector management tactics. Our conservative tier-1, quantitative risk assessment focused on acute, subchronic, and chronic exposures and cancer risks to military personnel after insecticide application and use of personal protective measures in different scenarios. Exposures were estimated for every scenario, chemical, and pathway. Acute, subchronic, and chronic risks were assessed using a margin of exposure (MOE) approach. Our MOE was the ratio of a no-observed-adverse-effect level (NOAEL) to an estimated exposure. MOEs were greater than the levels of concern (LOCs) for all surface residual and indoor space spraying exposures, except acute dermal exposure to lambda-cyhalothrin. MOEs were greater than the LOCs for all chemicals in the truck-mounted ultra-low-volume (ULV) exposure scenario. The aggregate cancer risk for permethrin exceeded 1 x 10(-6), but more realistic exposure refinements would reduce the cancer risk below that value. Overall, results indicate that health risks from exposures to insecticides and personal protective measures used by military personnel are low.

  12. Thermal Management in Fine-Grained 3-D Integrated Circuits

    OpenAIRE

    Iqbal, Md Arif; Macha, Naveen Kumar; Danesh, Wafi; Hossain, Sehtab; Rahman, Mostafizur

    2018-01-01

    For beyond 2-D CMOS logic, various 3-D integration approaches specially transistor based 3-D integrations such as monolithic 3-D [1], Skybridge [2], SN3D [3] holds most promise. However, such 3D architectures within small form factor increase hotspots and demand careful consideration of thermal management at all levels of integration [4] as stacked transistors are detached from the substrate (i.e., heat sink). Traditional system level approaches such as liquid cooling [5], heat spreader [6], ...

  13. Integrated model for line balancing with workstation inventory management

    OpenAIRE

    Dilip Roy; Debdip khan

    2010-01-01

    In this paper, we address the optimization of an integrated line balancing process with workstation inventory management. While doing so, we have studied the interconnection between line balancing and its conversion process. Almost each and every moderate to large manufacturing industry depends on a long and integrated supply chain, consisting of inbound logistic, conversion process and outbound logistic. In this sense an approach addresses a very general problem of integrated line balancing....

  14. Integrated Management of Residential Energy Resources

    Directory of Open Access Journals (Sweden)

    Antunes C. H.

    2012-10-01

    Full Text Available The increasing deployment of distributed generation systems based on renewables in the residential sector, the development of information and communication technologies and the expected evolution of traditional power systems towards smart grids are inducing changes in the passive role of end-users, namely with stimuli to change residential demand patterns. The residential user should be able to make decisions and efficiently manage his energy resources by taking advantages from his flexibility in load usage with the aim to minimize the electricity bill without depreciating the quality of energy services provided. The aim of this paper is characterizing electricity consumption in the residential sector and categorizing the different loads according to their typical usage, working cycles, technical constraints and possible degree of control. This categorization of end-use loads contributes to ascertain the availability of controllable loads to be managed as well as the different direct management actions that can be implemented. The ability to implement different management actions over diverse end-use load will increase the responsiveness of demand and potentially raises the willingness of end-users to accept such activities. The impacts on the aggregated national demand of large-scale dissemination of management systems that would help the end-user to make decisions regarding electricity consumption are predicted using a simulator that generates the aggregated residential sector electricity consumption under variable prices.

  15. Noospheric vector of management applied to the system of higher professional education

    Directory of Open Access Journals (Sweden)

    Yulia A. Mishina

    2017-01-01

    Full Text Available The aim of the research is to substantiate the necessity, expediency of the wide use of the noospheric management approaches, and technologies applied to the system of higher professional education in modern conditions. The materials and methods. Information base of the research is formed, based on education laws in Ukraine, Russia and the Donetsk People’s Republic, educational standards of higher professional education, as well as publications of scientists on the subject matter under study. In the given research it was used such methods: textological, analysis, generalization and modeling. The results. In the research, it is comprehensively examined the concept of noosphere, analyzed the modern theories and concepts of its development in relation to the development of society, an integral part of which is the system of education. It is indicated that there is the relationship between the noosphere and management in general, and with modern system of education, in particular. The concept of noospheric education is introduced and studied its impact on holistic  development of personality. The comparative characteristic of the structure and levels of the educational system of Ukraine, the Russian Federation and the Donetsk People’s Republic is performed; the types of educational institutions of the abovementioned states are compared. The structure of educational institution of higher professional education is proposed as a socio-economic system, managed from the perspective of the concept of noospheric education. The factors of competitiveness of educational institution of the higher school from the point of view of noospheric management are considered. Special attention is given to the internal factor of competitiveness of educational institutions, such as the quality of student life, because this position, particularly from the point of view of noospheric management, has a significant influence on the rating among consumers. The

  16. Integrating technologies for effective knowledge management

    Energy Technology Data Exchange (ETDEWEB)

    Beaugrand, F.S.; Curtis, T.A. [Public Petroleum Data Model, PPDM Association, Calgary, AB (Canada)

    2002-06-01

    In order to succeed in today's business environment, effective knowledge management strategies are needed along with effective tools to solve real business problems. Relational databases provide accessible and practical tools that can be used to manage corporate knowledge assets. However, technology is growing so rapidly that it is difficult and too expensive for individual corporations to pursue each line of development independently. Collaborative efforts are needed to improve access to shared knowledge. The PPDM Association is an international not for profit standards body that is working collaboratively with the petroleum exploration and production industry to develop standards for managing data and knowledge, spatially enabling data, standardizing data content and data exchange. The PPDM Association provides a vendor-neutral environment for development, technical support and a methodology for designing, developing and publishing technical deliverables.

  17. Nuclear safety culture and integrated risk management

    International Nuclear Information System (INIS)

    Joksimovich, V.; Orvis, D.D.

    1993-01-01

    A primary focus of nuclear safety is the prevention of large releases of radioactivity in the case of low-probability severe accidents. An analysis of the anatomy of nuclear (Chernobyl, Three Mile Island Unit 2) and nonnuclear (Challenger, Bhopal, Piper Alpha, etc.) severe accidents yields four broad categories of root causes: human (operating crew response), machine (design with its basic flaws), media (natural phenomena, operational considerations, political environment, commercial pressures, etc.)-providing triggering events, and management (basic organizational safety culture flaws). A strong management can minimize the contributions of humans, machines, and media to the risk arising from the operation of hazardous facilities. One way that management can have a powerful positive influence is through the establishment of a proper safety culture. The term safety culture is used as defined by the International Atomic Energy Agency's International Safety Advisory Group

  18. Managed care, vertical integration strategies and hospital performance.

    Science.gov (United States)

    Wang, B B; Wan, T T; Clement, J; Begun, J

    2001-09-01

    The purpose of this study is to examine the association of managed care with hospital vertical integration strategies, as well as to observe the relationships of different types of vertical integration with hospital efficiency and financial performance. The sample consists of 363 California short-term acute care hospitals in 1994. Linear structure equation modeling is used to test six hypotheses derived from the strategic adaptation model. Several organizational and market factors are controlled statistically. Results suggest that managed care is a driving force for hospital vertical integration. In terms of performance, hospitals that are integrated with physician groups and provide outpatient services (backward integration) have better operating margins, returns on assets, and net cash flows (p < 0.01). These hospitals are not, however, likely to show greater productivity. Forward integration with a long-term-care facility, on the other hand, is positively and significantly related to hospital productivity (p < 0.001). Forward integration is negatively related to financial performance (p < 0.05), however, opposite to the direction hypothesized. Health executives should be responsive to the growth of managed care in their local market and should probably consider providing more backward integrated services rather than forward integrated services in order to improve the hospital's financial performance in today's competitive health care market.

  19. THE PLACE OF OCCUPATIONAL HEALTH AND SAFETY MANAGEMENT SYSTEM IN THE INTEGRATED MANAGEMENT SYSTEM

    Directory of Open Access Journals (Sweden)

    Piotr Kafel

    2016-06-01

    Full Text Available The purpose of this paper is to analyze the place of occupational health and safety management system (OHSMS within the integrated management system. Implementation aspects of management systems are discussed, namely the different management system standards used for registration, for example ISO 14001, ISO 9001, OHSAS 18001, ISO 27001, the order in which they were implemented, the time required for each implementation, as well as the scope of integration of these management system standards into a single Integrated Management System and the level of integration. In order to do so, some of the results of a survey carried out in 81 organizations registered to at least two management systems selected from popular international standards, e.g.: ISO 9001, ISO 14001, OHSAS 18001, ISO/IEC 27001, ISO 22000 were used. OHSMS is not the system that is implemented as a first one. Usually it is implemented after or simultaneously with ISO 9001 and ISO 14001 standards. Time of implementation of MSSs in second and further round of implementation is shorter than during the implementation of first standards. There is a higher level of integration of implemented management standards in organizations where one of the standards in OHSMS, than in a companies without OHSMS. The paper analyses those sequences of management systems implementation of safety management systems with other system, that allow organizations to achieve higher levels of integration and presents a possible pattern for the companies initiating the integration process.

  20. Barriers to Asthma Management for School Nurses: An Integrative Review

    Science.gov (United States)

    Hanley Nadeau, Ellen; Toronto, Coleen E.

    2016-01-01

    Childhood asthma is a growing health concern. Asthma is the most common chronic illness of childhood and a leading cause of emergency room visits, hospitalizations, and school absenteeism. School nurses play a valuable role in asthma management. The purpose of this integrative review is to examine barriers to asthma management for school nurses in…

  1. Integral system of management quality - company quality assurance

    International Nuclear Information System (INIS)

    Dimitrovski, Aleksandar

    1999-01-01

    Integral System of Management Quality is imposed as a solution which in the future will be applied in the companies more frequently, provoked from the needs for solving management quality, working conditions, ecology, safety at work, way of leaving, etc. (Original)

  2. From Knowledge Theory to Management Practice: Towards an Integrated Approach.

    Science.gov (United States)

    Shin, Minsoo; Holden, Tony; Schmidt, Ruth A.

    2001-01-01

    Critically contrasts the three main schools of thought on knowledge and assesses the resulting implications for knowledge management. Presents a conceptual model to integrate theoretical and practical themes to serve as a framework for developing a future research agenda for the development of knowledge management business tools and applications.…

  3. Challenges of Integrated Pest Management in Sub-Saharan Africa

    NARCIS (Netherlands)

    Huis, van A.

    2009-01-01

    a response to the negative side effects of chemical control in the developed world, Integrated Pest Management (IPM) developed with an emphasis on reducing the role of pesticides. Later the role of natural enemies was recognized as being the cornerstone for sustainable pest management strategies.

  4. Integrating the traditional and the modern conflict management ...

    African Journals Online (AJOL)

    The study examines the modalities for integrating traditional and modern conflict management strategies in Nigeria using an analysis of relevant documents as well as Black's Social Control Theory and Thomas-Kilmann's Model of Conflict Management. The successful amalgamation of diverse groups has radically shifted ...

  5. Integration of Women into Management Positions: A Research Review.

    Science.gov (United States)

    Terborg, James R.

    This paper reviews the literature on the psychological and social processes involved in the integration of women into management positions. The author concentrates on two areas. First is the entry of women into management (including women's career choices, choice of organization, and the effects of these choices on the organization. These effects…

  6. Multidisciplinary management--an opportunity for service integration.

    Science.gov (United States)

    Cameron, M

    1997-01-01

    The management team of the future will enter an environment requiring facilitation, participation, clinical, and empowerment skills. Those individuals who possess a clinical orientation as well as business expertise will be sought to manage multidisciplinary units. The rapid changes in the health-care environment have forced organizations to restructure their operations. To achieve quality care, customer satisfaction, cost-effectiveness, and efficiency, service integration across the organization will be required. As we approach the 21st century, this standard will evolve until "all levels are managing patient care." Some of the restructuring trends occurring in the health-care industry have been collaboration service integration, management consolidation, and job elimination. The emphasis for the multidisciplinary manager of the future will include integrating the professional and clinical services, managing information, building community partnerships, promoting physician collaboration, and managing the change process. A model organization in the next century will move toward a people-oriented system with inclusion and empowerment initiatives. Service integration will affect all organizations, but the disciplines within the Clinical Support System will be the most affected. Future opportunities of leadership will exist for pathologists, nurses, or medical technologists as the professional silos of managers and clinicians continue to crumble.

  7. Supply Chain Management and Sustainability : Procrastinating Integration in Mainstream Research

    NARCIS (Netherlands)

    De Brito, M.P.; Van der Laan, E.A.

    2010-01-01

    Research has pointed out opportunities and research agendas to integrate sustainability issues with supply chain and operations management. However, we find that it is still not mainstream practice to systematically take a sustainability approach in tackling supply chain and operations management

  8. Development and Implementation of Integrated Pest Management in ...

    African Journals Online (AJOL)

    Nafiisah

    This paper reviews the status of Integrated Pest Management (IPM) research in. Mauritius and also reports on the successful cases of IPM implementation during ... Tool. Activity. Status. Source. Biological control. Introduce parasitoids .... 10 g sugar in 1 L of water) in plastic bottles as one option to manage fruit flies in.

  9. The integration of quality management functions within a university ...

    African Journals Online (AJOL)

    According to a recent study, institutions of higher learning in South Africa fail to a great extent to integrate the key management functions that are fundamental to effective quality management. This article argues that the effective promotion of quality of a university's core business depends to a large extent on the ability of an ...

  10. A review of Integrated Management of Childhood Illness (IMCI ...

    African Journals Online (AJOL)

    The Integrated Management of Childhood Illness (IMCI) strategy is the primary child-care approach of choice for South Africa.1,2 IMCI training was introduced into ... by nurse practitioner and doctor alike in empowering them to make easy, evidence-based decisions in the management of sick children at first contact level.

  11. The Integrative University: Why University Management Is Different

    Science.gov (United States)

    Temple, Paul

    2008-01-01

    Managing universities "is" different from managing in most other sorts of organisation. In this article, the author shows why this claim is more than just special pleading, and how it relates to the particular form of the organisation. Appreciating their integrative aspects helps people to understand some of the difficulties that they regularly…

  12. Integrating Cybersecurity into the Program Management Organization

    Science.gov (United States)

    2015-05-13

    penalty for failing to comply with a collection of information if it does not display a currently valid OMB control number. 1. REPORT DATE 13 MAY 2015 2...Threat to our National Economy DOD Cybersecurity Gaps Could Be Canary in Federal Acquisition Coal Mine Intangible Assets Create Vulnerabilities...operational approach integrates with current or planned CONOPS, BCP, information architecture, programs or initiatives Development  Approach to

  13. Integrating Total Quality Management (TQM) and hazardous waste management

    Energy Technology Data Exchange (ETDEWEB)

    Kirk, Nancy [Colorado State Univ., Fort Collins, CO (United States)

    1993-11-01

    The Resource Conservation and Recovery Act (RCRA) of 1976 and its subsequent amendments have had a dramatic impact on hazardous waste management for business and industry. The complexity of this law and the penalties for noncompliance have made it one of the most challenging regulatory programs undertaken by the Environmental Protection Agency (EPA). The fundamentals of RCRA include ``cradle to grave`` management of hazardous waste, covering generators, transporters, and treatment, storage, and disposal facilities. The regulations also address extensive definitions and listing/identification mechanisms for hazardous waste along with a tracking system. Treatment is favored over disposal and emphasis is on ``front-end`` treatment such as waste minimization and pollution prevention. A study of large corporations such as Xerox, 3M, and Dow Chemical, as well as the public sector, has shown that well known and successful hazardous waste management programs emphasize pollution prevention and employment of techniques such as proactive environmental management, environmentally conscious manufacturing, and source reduction. Nearly all successful hazardous waste programs include some aspects of Total Quality Management, which begins with a strong commitment from top management. Hazardous waste management at the Rocky Flats Plant is further complicated by the dominance of ``mixed waste`` at the facility. The mixed waste stems from the original mission of the facility, which was production of nuclear weapons components for the Department of Energy (DOE). A Quality Assurance Program based on the criterion in DOE Order 5700.6C has been implemented at Rocky Flats. All of the elements of the Quality Assurance Program play a role in hazardous waste management. Perhaps one of the biggest waste management problems facing the Rocky Flats Plant is cleaning up contamination from a forty year mission which focused on production of nuclear weapon components.

  14. Integrating Total Quality Management (TQM) and hazardous waste management

    International Nuclear Information System (INIS)

    Kirk, N.

    1993-01-01

    The Resource Conservation and Recovery Act (RCRA) of 1976 and its subsequent amendments have had a dramatic impact on hazardous waste management for business and industry. The complexity of this law and the penalties for noncompliance have made it one of the most challenging regulatory programs undertaken by the Environmental Protection Agency (EPA). The fundamentals of RCRA include ''cradle to grave'' management of hazardous waste, covering generators, transporters, and treatment, storage, and disposal facilities. The regulations also address extensive definitions and listing/identification mechanisms for hazardous waste along with a tracking system. Treatment is favored over disposal and emphasis is on ''front-end'' treatment such as waste minimization and pollution prevention. A study of large corporations such as Xerox, 3M, and Dow Chemical, as well as the public sector, has shown that well known and successful hazardous waste management programs emphasize pollution prevention and employment of techniques such as proactive environmental management, environmentally conscious manufacturing, and source reduction. Nearly all successful hazardous waste programs include some aspects of Total Quality Management, which begins with a strong commitment from top management. Hazardous waste management at the Rocky Flats Plant is further complicated by the dominance of ''mixed waste'' at the facility. The mixed waste stems from the original mission of the facility, which was production of nuclear weapons components for the Department of Energy (DOE). A Quality Assurance Program based on the criterion in DOE Order 5700.6C has been implemented at Rocky Flats. All of the elements of the Quality Assurance Program play a role in hazardous waste management. Perhaps one of the biggest waste management problems facing the Rocky Flats Plant is cleaning up contamination from a forty year mission which focused on production of nuclear weapon components

  15. Development of integrated accident management assessment technology

    International Nuclear Information System (INIS)

    Jung, Won Dea; Ha, Jae Joo; Jin, Young Ho

    2002-04-01

    This project aims to develop critical technologies for accident management through securing evaluation frameworks and supporting tools, in order to enhance capabilities coping with severe accidents. For the research goal, firstly under the viewpoint of accident prevention, on-line risk monitoring system and the analysis framework for human error have been developed. Secondly, the training/supporting systems including the training simulator and the off-site risk evaluation system have been developed to enhance capabilities coping with severe accidents. Four kinds of research results have been obtained from this project. Firstly, the framework and taxonomy for human error analysis has been developed for accident management. As the second, the supporting system for accident managements has been developed. Using data that are obtained through the evaluation of off-site risk for Younggwang site, the risk database as well as the methodology for optimizing emergency responses has been constructed. As the third, a training support system, SAMAT, has been developed, which can be used as a training simulator for severe accident management. Finally, on-line risk monitoring system, DynaRM, has been developed for Ulchin 3 and 4 unit

  16. Integrated management of thesis using clustering method

    Science.gov (United States)

    Astuti, Indah Fitri; Cahyadi, Dedy

    2017-02-01

    Thesis is one of major requirements for student in pursuing their bachelor degree. In fact, finishing the thesis involves a long process including consultation, writing manuscript, conducting the chosen method, seminar scheduling, searching for references, and appraisal process by the board of mentors and examiners. Unfortunately, most of students find it hard to match all the lecturers' free time to sit together in a seminar room in order to examine the thesis. Therefore, seminar scheduling process should be on the top of priority to be solved. Manual mechanism for this task no longer fulfills the need. People in campus including students, staffs, and lecturers demand a system in which all the stakeholders can interact each other and manage the thesis process without conflicting their timetable. A branch of computer science named Management Information System (MIS) could be a breakthrough in dealing with thesis management. This research conduct a method called clustering to distinguish certain categories using mathematics formulas. A system then be developed along with the method to create a well-managed tool in providing some main facilities such as seminar scheduling, consultation and review process, thesis approval, assessment process, and also a reliable database of thesis. The database plays an important role in present and future purposes.

  17. INTEGRATION OF PROGRESS STRATEGY IN PROJECT MANAGEMENT

    OpenAIRE

    Дмитрий Георгиевич БЕЗУГЛЫЙ

    2015-01-01

    The methods and tools of the developed project promotion, the planning system of promotion strategy are suggested; the main approaches used in the project promotion have been identified. The conclusions about the importance, necessity and role in the promotion of a holistic project management system have been made.

  18. Management of Uncertain Data - towards unattended integration

    NARCIS (Netherlands)

    de Keijzer, Ander

    2008-01-01

    In recent years, the need to support uncertain data has increased. Sensor applications, for example, are dealing with the inherent uncertainty about the readings of the sensors. Current database management systems are not equipped to deal with this uncertainty, other than as a user defined

  19. Steam generator asset management: integrating technology and asset management

    International Nuclear Information System (INIS)

    Shoemaker, P.; Cislo, D.

    2006-01-01

    Asset Management is an established but often misunderstood discipline that is gaining momentum within the nuclear generation industry. The global impetus behind the movement toward asset management is sustainability. The discipline of asset management is based upon three fundamental aspects; key performance indicators (KPI), activity-based cost accounting, and cost benefits/risk analysis. The technology associated with these three aspects is fairly well-developed, in all but the most critical area; cost benefits/risk analysis. There are software programs that calculate, trend, and display key-performance indicators to ensure high-level visibility. Activity-based costing is a little more difficult; requiring a consensus on the definition of what comprises an activity and then adjusting cost accounting systems to track. In the United States, the Nuclear Energy Institute's Standard Nuclear Process Model (SNPM) serves as the basis for activity-based costing. As a result, the software industry has quickly adapted to develop tracking systems that include the SNPM structure. Both the KPI's and the activity-based cost accounting feed the cost benefits/risk analysis to allow for continuous improvement and task optimization; the goal of asset management. In the case where the benefits and risks are clearly understood and defined, there has been much progress in applying technology for continuous improvement. Within the nuclear generation industry, more specialized and unique software systems have been developed for active components, such as pumps and motors. Active components lend themselves well to the application of asset management techniques because failure rates can be established, which serves as the basis to quantify risk in the cost-benefits/risk analysis. A key issue with respect to asset management technologies is only now being understood and addressed, that is how to manage passive components. Passive components, such as nuclear steam generators, reactor vessels

  20. Multiple sclerosis care: an integrated disease-management model.

    Science.gov (United States)

    Burks, J

    1998-04-01

    A disease-management model must be integrated, comprehensive, individual patient focused and outcome driven. In addition to high quality care, the successful model must reduce variations in care and costs. MS specialists need to be intimately involved in the long-term care of MS patients, while not neglecting primary care issues. A nurse care manager is the "glue" between the managed care company, health care providers and the patient/family. Disease management focuses on education and prevention, and can be cost effective as well as patient specific. To implement a successful program, managed care companies and health care providers must work together.

  1. "INTEGRATED QUALITY MANAGEMENT" AS A SUBJECT IN HIGHER EDUCATION CURRICULUM

    Directory of Open Access Journals (Sweden)

    Stevan Živojinović

    2007-03-01

    Full Text Available The importance of introduction of "Integrated quality management" into higher education curricula arises from the need for students to grasp synergetic application of new and advanced approaches to theoretical and practical management quality and process based management in particular as well as understanding a unified concept which improves conformity and linking of all levels in management hierarchy (normative, strategic and operational toward accomplishment of successful business performance. A curriculum is proposed (as a contribution to a map of necessary knowledge to be expected from prospective quality personnel with appropriate topics in accordance with studies objective and chosen up-to-date options of management concepts and methods.

  2. Managing the physics of the economics of integrated health care.

    Science.gov (United States)

    Zismer, Daniel K; Werner, Mark J

    2012-01-01

    The physics metaphor, as applied to the economics (and financial performance) of the integrated health system, seems appropriate when considered together with the nine principles of management framework provided. The nature of the integrated design enhances leaders' management potential as they consider organizational operations and strategy in the markets ahead. One question begged by this argument for the integrated design is the durability, efficiency and ultimate long-term survivability of the more "traditional" community health care delivery models, which, by design, are fragmented, internally competitive and less capital efficient. They also cannot exploit the leverage of teams, optimal access management or the pursuit of revenues made available in many forms. For those who wish to move from the traditional to the more integrated community health system designs (especially those who have not yet started the journey), the path requires: * Sufficient balance sheet capacity to fund the integration process-especially as the model requires physician practice acquisitions and electronic health record implementations * A well-prepared board13, 14 * A functional, durable and sustainable physician services enterprise design * A redesigned organizational and governance structure * Favorable internal financial incentives alignment design * Effective accountable physician leadership * Awareness that the system is not solely a funding strategy for acquired physicians, rather a fully -.. committed clinical and business model, one in which patient-centered integrated care is the core service (and not acute care hospital-based services) A willingness to create and exploit the implied and inherent potential of an integrated design and unified brand Last, it's important to remember that an integrated health system is a tool that creates a "new potential" (a physics metaphor reference, one last time). The design doesn't operate itself. Application of the management principles

  3. Clarifying the Imperative of Integration Research for Sustainable Environmental Management

    Directory of Open Access Journals (Sweden)

    Stephen Dovers

    2005-01-01

    Full Text Available This paper discusses why integration is important in doing research for developing policy and practice of sustainable environmental management. The imperative of integration includes environmental, social, economic, and other disciplinary considerations, as well as stakeholder interests. However, what is meant by integration is not always clear. While the imperative is being increasingly enunciated, the challenges it presents are difficult and indicate a long term pursuit. This paper clarifies the different dimensions of integration, as an important preliminary step toward advancing mutual understanding and the development of approaches. The paper identifies the driving forces for integration, discusses when integration is required, categorises forms of integration, and proposes principles to inform research programs and projects.

  4. Integrating total quality management in a library setting

    CERN Document Server

    Jurow, Susan

    2013-01-01

    Improve the delivery of library services by implementing total quality management (TQM), a system of continuous improvement employing participative management and centered on the needs of customers. Although TQM was originally designed for and successfully applied in business and manufacturing settings, this groundbreaking volume introduces strategies for translating TQM principles from the profit-based manufacturing sector to the library setting. Integrating Total Quality Management in a Library Setting shows librarians how to improve library services by implementing strategies such as employ

  5. TWRS safety and technical integration risk management plan

    International Nuclear Information System (INIS)

    Fordham, R.A.

    1996-01-01

    The objectives of the Tank Waste Remediation System (TWRS) Safety and Technical Integration (STI) programmatic risk management program are to assess, analyze, and handle risks associated with TWRS STI responsibilities and to communicate information about the actions being taken and the results to enable decision making. The objective of this TWRS STI Risk Management Plan is to communicate a consistent approach to risk management that will be used by the organization

  6. Integrated project risk management of nuclear power projects

    International Nuclear Information System (INIS)

    Wang Xiaohui; Xu Yuanhui

    2001-01-01

    The concept and the features of risks in nuclear power projects are introduced, and in terms of nuclear power projects' own features, the Nuclear Power Project Integrated Risk Management Model is presented. The identification, estimation, evaluation, response plan development, control of risks and the theoretical basis of risk management are discussed. The model has feedback and control functions in order to control and manage the risks dynamically

  7. Integrated flexible capacity and inventory management under flexible capacity uncertainty

    OpenAIRE

    Paç, Mehmet Fazıl

    2006-01-01

    Cataloged from PDF version of article. In a manufacturing environment with volatile demand, inventory management can be coupled with dynamic capacity adjustments for handling the fluctuations more effectively. In this study we consider the integrated management of inventory and flexible capacity management under seasonal stochastic demand and uncertain labor supply. The capacity planning problem is investigated from the workforce planning perspective. We consider a manufactu...

  8. INTEGRATION MECHANISMS OF IMPROVEMENT OF HUMAN RESOURCES MANAGEMENT

    Directory of Open Access Journals (Sweden)

    Vera A. Akimenko

    2013-01-01

    Full Text Available In the current economic conditions, the efficiency of business processes of an organization is determined by the quality of the staff. Therefore, actual is the creation and application of new approaches to the management of human re-sources. The article presents a comparative analysis of management practices and their impact on the effectiveness of personnel management, the mechanism of their integration to improve the efficiency of the process.

  9. Integrated management system implementation strategy for PUSPATI TRIGA Reactor

    International Nuclear Information System (INIS)

    Phongsakorn Prak Tom; Shaharum Ramli; Mohamad Azman Che Mat Isa; Shahirah Abdul Rahman; Mohd Zaid Mohamed; Mat Zin Mat Husin; Nurfazila Husain; Mohamad Puad Abu

    2012-01-01

    Integrated Management System (IMS) designed to fulfil the requirements integrates safety, health, environmental, security, quality and economic elements. PUSPATI TRIGA Reactor (RTP) is currently implementing the Quality Assurance Program (QAP) and looking toward implementation of IMS. This paper discussed the implementation strategy of IMS for RTP. There are nine steps of IMS implementation strategy. In implementation of IMS, Gantt chart is useful project management tool in managing the project frame work. IMS is intended as a tool to enable the continuous development of safety culture and achieve higher safety levels. (author)

  10. Integrated project management information systems: the French nuclear industry experience

    International Nuclear Information System (INIS)

    Jacquin, J.-C.; Caupin, G.-M.

    1990-01-01

    The article discusses the desirability of integrated project management systems within the French nuclear power industry. Change in demand for nuclear generation facilities over the last two decades has necessitated a change of policy concerning organization, cost and planning within the industry. Large corporate systems can benefit from integrating equipment and bulk materials tracking. Project management for the nuclear industry will, in future, need to incorporate computer aided design tools and project management information systems data bases as well as equipment and planning data. (UK)

  11. Integrated project management information systems: the French nuclear industry experience

    Energy Technology Data Exchange (ETDEWEB)

    Jacquin, J.-C.; Caupin, G.-M.

    1990-03-01

    The article discusses the desirability of integrated project management systems within the French nuclear power industry. Change in demand for nuclear generation facilities over the last two decades has necessitated a change of policy concerning organization, cost and planning within the industry. Large corporate systems can benefit from integrating equipment and bulk materials tracking. Project management for the nuclear industry will, in future, need to incorporate computer aided design tools and project management information systems data bases as well as equipment and planning data. (UK).

  12. Integrated Risk Management Within NASA Programs/Projects

    Science.gov (United States)

    Connley, Warren; Rad, Adrian; Botzum, Stephen

    2004-01-01

    As NASA Project Risk Management activities continue to evolve, the need to successfully integrate risk management processes across the life cycle, between functional disciplines, stakeholders, various management policies, and within cost, schedule and performance requirements/constraints become more evident and important. Today's programs and projects are complex undertakings that include a myriad of processes, tools, techniques, management arrangements and other variables all of which must function together in order to achieve mission success. The perception and impact of risk may vary significantly among stakeholders and may influence decisions that may have unintended consequences on the project during a future phase of the life cycle. In these cases, risks may be unintentionally and/or arbitrarily transferred to others without the benefit of a comprehensive systemic risk assessment. Integrating risk across people, processes, and project requirements/constraints serves to enhance decisions, strengthen communication pathways, and reinforce the ability of the project team to identify and manage risks across the broad spectrum of project management responsibilities. The ability to identify risks in all areas of project management increases the likelihood a project will identify significant issues before they become problems and allows projects to make effective and efficient use of shrinking resources. By getting a total team integrated risk effort, applying a disciplined and rigorous process, along with understanding project requirements/constraints provides the opportunity for more effective risk management. Applying an integrated approach to risk management makes it possible to do a better job at balancing safety, cost, schedule, operational performance and other elements of risk. This paper will examine how people, processes, and project requirements/constraints can be integrated across the project lifecycle for better risk management and ultimately improve the

  13. Integrated information and logistics management, quality management and firm performance of pork processing industry in China

    NARCIS (Netherlands)

    Han, J.; Trienekens, J.H.; Omta, S.W.F.

    2009-01-01

    Purpose – This paper seeks to discuss the interactions amongst integrated information technology (IT), integrated logistics management, quality management practices and firm performance of pork processors in China. Design/methodology/approach – A conceptual framework was developed by examining the

  14. Integrated mosquito larval source management reduces larval numbers in two highland villages in western Kenya

    Directory of Open Access Journals (Sweden)

    Imbahale Susan S

    2012-05-01

    that arose due to human activities. Involvement of community members in control programs would be beneficial in the long term once they understand the role they play in malaria transmission. Apart from the need for communities to be educated on their role in malaria transmission, there is a need to develop and test strategies that can easily be accessed and hence be used by the affected communities. The proposed LSM strategies target outdoor immature mosquitoes and hence can complement well with control measures that target indoor resting vectors. Therefore inclusion of LSM in Integrated Vector Management (IVM program would be beneficial.

  15. Integrated remotely sensed datasets for disaster management

    OpenAIRE

    McCarthy, Tim; Farrell, Ronan; Curtis, Andrew; Fotheringham, A. Stewart

    2008-01-01

    Video imagery can be acquired from aerial, terrestrial and marine based platforms and has been exploited for a range of remote sensing applications over the past two decades. Examples include coastal surveys using aerial video, routecorridor infrastructures surveys using vehicle mounted video cameras, aerial surveys over forestry and agriculture, underwater habitat mapping and disaster management. Many of these video systems are based on interlaced, television standards such as North...

  16. Integral management of hazardous materials transport

    International Nuclear Information System (INIS)

    Moran, M.

    2002-01-01

    As a result of outsourcing transport operations and complementary services on the part of the producers and shippers, there is a growing demand for global services that integrate the whole external logistics value chain, the latter being understood to signify the process that includes the storage, transport (monomodal or bi-multi-modal) and delivery to destination. This circumstance has obliged transport firms to undertake a process of internal transformation: from offering an activity purely of transport to becoming logistics operators. Express Truck, S. a. (hereinafter ETSA) could not ignore this market requirement. We will explain the evolutionary process of ETSA in this sense. (Author)

  17. A novel system for simultaneous or sequential integration of multiple gene-loading vectors into a defined site of a human artificial chromosome.

    Science.gov (United States)

    Suzuki, Teruhiko; Kazuki, Yasuhiro; Oshimura, Mitsuo; Hara, Takahiko

    2014-01-01

    Human artificial chromosomes (HACs) are gene-delivery vectors suitable for introducing large DNA fragments into mammalian cells. Although a HAC theoretically incorporates multiple gene expression cassettes of unlimited DNA size, its application has been limited because the conventional gene-loading system accepts only one gene-loading vector (GLV) into a HAC. We report a novel method for the simultaneous or sequential integration of multiple GLVs into a HAC vector (designated as the SIM system) via combined usage of Cre, FLP, Bxb1, and φC31 recombinase/integrase. As a proof of principle, we first attempted simultaneous integration of three GLVs encoding EGFP, Venus, and TdTomato into a gene-loading site of a HAC in CHO cells. These cells successfully expressed all three fluorescent proteins. Furthermore, microcell-mediated transfer of HACs enabled the expression of those fluorescent proteins in recipient cells. We next demonstrated that GLVs could be introduced into a HAC one-by-one via reciprocal usage of recombinase/integrase. Lastly, we introduced a fourth GLV into a HAC after simultaneous integration of three GLVs by FLP-mediated DNA recombination. The SIM system expands the applicability of HAC vectors and is useful for various biomedical studies, including cell reprogramming.

  18. A novel system for simultaneous or sequential integration of multiple gene-loading vectors into a defined site of a human artificial chromosome.

    Directory of Open Access Journals (Sweden)

    Teruhiko Suzuki

    Full Text Available Human artificial chromosomes (HACs are gene-delivery vectors suitable for introducing large DNA fragments into mammalian cells. Although a HAC theoretically incorporates multiple gene expression cassettes of unlimited DNA size, its application has been limited because the conventional gene-loading system accepts only one gene-loading vector (GLV into a HAC. We report a novel method for the simultaneous or sequential integration of multiple GLVs into a HAC vector (designated as the SIM system via combined usage of Cre, FLP, Bxb1, and φC31 recombinase/integrase. As a proof of principle, we first attempted simultaneous integration of three GLVs encoding EGFP, Venus, and TdTomato into a gene-loading site of a HAC in CHO cells. These cells successfully expressed all three fluorescent proteins. Furthermore, microcell-mediated transfer of HACs enabled the expression of those fluorescent proteins in recipient cells. We next demonstrated that GLVs could be introduced into a HAC one-by-one via reciprocal usage of recombinase/integrase. Lastly, we introduced a fourth GLV into a HAC after simultaneous integration of three GLVs by FLP-mediated DNA recombination. The SIM system expands the applicability of HAC vectors and is useful for various biomedical studies, including cell reprogramming.

  19. Integrated Data Management for Mobile Services in the Real World

    DEFF Research Database (Denmark)

    Hage, C.; Jensen, Christian Søndergaard; Pedersen, Torben Bach

    2003-01-01

    Market research companies predict a huge market for services to be delivered to mobile users. Services in5 clude route guidance, point-of-interest search, metering services such as road pricing and parking payment, traffic monitoring, etc. We believe that no single such service will be the killer...... service, but that suites of integrated services are called for. Such integrated services reuse integrated content obtained from multiple content providers. This paper describes concepts and techniques underlying the data management system deployed by a Danish mobile content integrator. While geo...

  20. Short-term electricity prices forecasting based on support vector regression and Auto-regressive integrated moving average modeling

    International Nuclear Information System (INIS)

    Che Jinxing; Wang Jianzhou

    2010-01-01

    In this paper, we present the use of different mathematical models to forecast electricity price under deregulated power. A successful prediction tool of electricity price can help both power producers and consumers plan their bidding strategies. Inspired by that the support vector regression (SVR) model, with the ε-insensitive loss function, admits of the residual within the boundary values of ε-tube, we propose a hybrid model that combines both SVR and Auto-regressive integrated moving average (ARIMA) models to take advantage of the unique strength of SVR and ARIMA models in nonlinear and linear modeling, which is called SVRARIMA. A nonlinear analysis of the time-series indicates the convenience of nonlinear modeling, the SVR is applied to capture the nonlinear patterns. ARIMA models have been successfully applied in solving the residuals regression estimation problems. The experimental results demonstrate that the model proposed outperforms the existing neural-network approaches, the traditional ARIMA models and other hybrid models based on the root mean square error and mean absolute percentage error.

  1. Improving integration for integrated coastal zone management: an eight country study.

    Science.gov (United States)

    Portman, M E; Esteves, L S; Le, X Q; Khan, A Z

    2012-11-15

    Integrated coastal zone management (ICZM) is a widely accepted approach for sustainable management of the coastal environment. ICZM emphasizes integration across sectors, levels of government, uses, stakeholders, and spatial and temporal scales. While improving integration is central to progress in ICZM, the role of and the achievement of integration remain understudied. To further study these two points, our research analyzes the performance of specific mechanisms used to support ICZM in eight countries (Belgium, India, Israel, Italy, Portugal, Sweden, UK, and Vietnam). The assessment is based on a qualitative comparative analysis conducted through the use of two surveys. It focuses on five ICZM mechanisms (environmental impact assessment; planning hierarchy; setback lines; marine spatial planning, and regulatory commission) and their role in improving integration. Our findings indicate that certain mechanisms enhance specific types of integration more effectively than others. Environmental impact assessment enhances science-policy integration and can be useful to integrate knowledge across sectors. Planning hierarchy and regulatory commissions are effective mechanisms to integrate policies across government levels, with the latter also promoting public-government integration. Setback lines can be applied to enhance integration across landscape units. Marine spatial planning is a multi-faceted mechanism with the potential to promote all types of integration. Policy-makers should adopt the mechanisms that are suited to the type of integration needed. Results of this study also contribute to evidence-based coastal management by identifying the most common impediments related to the mechanisms of integration in the eight studied countries. Copyright © 2012 Elsevier B.V. All rights reserved.

  2. Evaluation of chemical spraying and environmental management efficacy in areas with minor previous application of integrated control actions for visceral leishmaniasis in Brazil.

    Science.gov (United States)

    Lara-Silva, Fabiana de Oliveira; Michalsky, Érika Monteiro; Fortes-Dias, Consuelo Latorre; Fiuza, Vanessa de Oliveira Pires; Dias, Edelberto Santos

    2017-12-01

    Leishmaniases are vector-borne diseases that are transmitted to humans through the bite of Leishmania-infected phlebotomine sand flies (Diptera:Psychodidae). The main proved vector of visceral leishmaniais (VL) in the New World - Lutzomyia longipalpis - is well-adapted to urban areas and has extensive distribution within the five geographical regions of Brazil. Integrated public health actions directed for the vector, domestic reservoir and humans for the control of VL are preferentially applied in municipalities with higher epidemiological risk of transmission. In this study, we evaluated the individual impact of two main vector control actions - chemical spraying and environmental management - in two districts with no reported cases of human VL. Although belonging to an endemic municipality for VL in Brazil, the integrated control actions have not been applied in these districts due to the absence of human cases. The number of L. longipalpis captured in a two-year period was used as indicator of the population density of the vector. After chemical spraying a tendency of reduction in L. longipalpis was observed but with no statistical significance compared to the control. Environmental management was effective in that reduction and it may help in the control of VL by reducing the population density of the vector in a preventive and more permanent action, perhaps associated with chemical spraying. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. Effects of top management involvement in integrated marketing communications

    Directory of Open Access Journals (Sweden)

    Nina Hočevar

    2007-12-01

    Full Text Available There is scarce empirical evidence in the academic literature of how top management involvement influences the degree of integrated marketing communications. At the same time, some authors believe that this relationship should be explored more extensively.In this paper we present one possible approach to investigating the relationship between top management involvement and the degree of integrated marketing communications. Our research established that a greater involvement of top management in marketing communications could be associated with a higher degree of IMC. Investigating the relationship between management and IMC is indeed at a very early stage. We suggest that this study has provided a basis for future research on the relationship between top management involvement in marketing communications and the degree of IMC.

  4. Integrating risk management into the baselining process

    International Nuclear Information System (INIS)

    Jennett, N.; Tonkinson, A.

    1994-01-01

    These processes work together in building the project (comprised of the technical, schedule, and cost baselines) against which performance is measured and changes to the scope, schedule and cost of a project are managed and controlled. Risk analysis is often performed as the final element of the scheduling or estimating processes, a precursor to establishing cost and schedule contingency. However, best business practices dictate that information that may be crucial to the success of a project be analyzed and incorporated into project planning as soon as it is available and usable. The purpose or risk management is not to eliminate risk. Neither is it intended to suggest wholesale re-estimating and re-scheduling of a project. Rather, the intent is to make provisions to reduce and control the schedule and/or cost ramifications of risk by anticipating events and conditions that cannot be reliably planned for and which have the potential to negatively impact accomplishment of the technical objectives and requirements of the project

  5. The innovation and practice of management improved by integration management information system in nuclear enterprise

    International Nuclear Information System (INIS)

    Zhang Fan; Cheng Lihong; Li Qisheng; Ge Zhengfa

    2012-01-01

    This article expounds that Hunan Taohuajiang Nuclear Power Company generally programs the route of company's core business and implements its integration through referencing the experience of informationization construction of other enterprises at the beginning of the foundation of this company, and summarizes the experience of system construction and analyses the innovation and signification of the integrative management information system to the nu- clear power enterprise management from data unified, resources sharing and business electronic and the management improvement of this company. (authors)

  6. A Review of Ocean Management and Integrated Resource Management Programs from Around the World

    OpenAIRE

    , Seaplan

    2018-01-01

    This draft report is one of several prepared under contract to the Massachusetts Ocean Partnership (MOP) to support the Massachusetts Executive Office of Energy and Environmental Affairs (EOEEA) in its development of the integrated coastal ocean management plan mandated by the Massachusetts Oceans Act of 2008. The purpose of this report was to inventory and review ocean management and integrated resource management programs from around the world, including the United States, Europe, Australia...

  7. Role of plant pathology in integrated pest management.

    Science.gov (United States)

    Jacobsen, B J

    1997-01-01

    Integrated Pest Management (IPM) is a paradigm that is widely adopted by all pest control disciplines but whose early definitions and philosophical basis belong to entomologists. Plant pathology research and extension work has historically emphasized integration of several control strategies and fits both historical and modern definitions of IPM. While the term IPM has been used only sparingly in the phytopathology literature, the integrated disease management strategies emphasized are now considered to be at the forefront of ecologically based or biointensive pest management. While IPM is broadly endorsed by crop protection disciplines, farmers, other agriculturalists, and consumers, the potential for Integrated Pest Management has not been fully realized. Most IPM programs reflect a package of tools and decision aids for individual crop insect, weed, nematode, and plant disease management. IPM programs that integrate all types of pests with the agroecosystem, crop growth and loss models still await the formation of interdisciplinary teams focusing on growers needs. Lack of funding for both discipline and interdisciplinary developmental research and implementation is responsible for the paucity of comprehensive IPM programs for the majority of the U.S. crop acreage. This review explores the origins and evolution of the IPM paradigm and reviews efforts to achieve the body of knowledge and implementation structure to achieve IPM's full potential.

  8. Toward population management in an integrated care model.

    Science.gov (United States)

    Maddux, Franklin W; McMurray, Stephen; Nissenson, Allen R

    2013-01-01

    Under the Patient Protection and Affordable Care Act of 2010, accountable care organizations (ACOs) will be the primary mechanism for achieving the dual goals of high-quality patient care at managed per capita costs. To achieve these goals in the newly emerging health care environment, the nephrology community must plan for and direct integrated delivery and coordination of renal care, focusing on population management. Even though the ESRD patient population is a complex group with comorbid conditions that may confound integration of care, the nephrology community has unique experience providing integrated care through ACO-like programs. Specifically, the recent ESRD Management Demonstration Project sponsored by the Centers for Medicare & Medicaid Services and the current ESRD Prospective Payment System with it Quality Incentive Program have demonstrated that integrated delivery of renal care can be accomplished in a manner that provides improved clinical outcomes with some financial margin of savings. Moving forward, integrated renal care will probably be linked to provider performance and quality outcomes measures, and clinical integration initiatives will share several common elements, namely performance-based payment models, coordination of communication via health care information technology, and development of best practices for care coordination and resource utilization. Integration initiatives must be designed to be measured and evaluated, and, consistent with principles of continuous quality improvement, each initiative will provide for iterative improvements of the initiative. © 2013 S. Karger AG, Basel.

  9. A SURVEY ON INDIAN EXPERIENCE ON INTEGRATED MANAGEMENT STANDARDS (IMS

    Directory of Open Access Journals (Sweden)

    H. Khanna

    2009-09-01

    Full Text Available Adoption of management systems standards is a key issue in manufacturing industry in India. Following the global trend quality and environmental issues are gaining importance. However the number of ISO 14001 certified companies are much less in India as compared to ISO 9001. The integration of ISO 14001 with ISO 9001 may help companies to sustain competitive advantage and overcome disappointments with quality standards and in turn encourage companies to adopt good environmental practices. The aim of this research is to study the implementation of integrated management standards (IMS by the manufacturing organizations in India. The different aspects of integration and benefits of IMS implementation are analyzed. This r esearch is based on empirical study carried out in Indian manufacturing firms, involving the application of a questionnaire. This questionnaire was tested on 50 manufacturing companies in India. The study reveals that focus on stakeholders; top management commitment and training are critical success factors for implementation of IMS. The main benefits of integration are discussed. The small sample size is one of the major limitations of this study. The paper informs the managers in manufacturing organizations and practitioners of management system standards especially in developing countries about IMS and will enable them to adopt IMS in future so that those organizations may not implement multiple and overlapping MSS(Management System Standards.

  10. Pipeline four-dimension management is the trend of pipeline integrity management in the future

    Energy Technology Data Exchange (ETDEWEB)

    Shaohua, Dong; Feifan; Zhongchen, Han [China National Petroleum Corporation (CNPC), Beijing (China)

    2009-07-01

    Pipeline integrity management is essential for today's operators to operate their pipelines safety and cost effectively. The latest developments of pipeline integrity management around the world are involved with change of regulation, industry standard and innovation of technology. And who know the trend of PIM in the future, which can be answered in the paper. As a result, the concept of P4DM was set up firstly in the world. The paper analyzed the pipeline HSE management, pipeline integrity management (PIM) and asset integrity management (AIM), the problem of management was produced, and also the Pipeline 4-dimension Management (P4DM) theory was brought forward. According to P4DM, from the hierarchy of P4DM, the management elements, fields, space and time was analyzed. The main content is P4DM integrate the space geography location and time, control and manage the pipeline system in whole process, anywhere and anytime. It includes the pipeline integrity, pipeline operation and emergency, which is integrated by IT system. It come true that the idea, solution, technology, organization, manager alternately intelligently control the process of management. What the paper talks about included the definition of pipeline 4D management, the research develop of P4DM, the theory of P4DM, the relationship between P4DM and PIM, the technology basis of P4DM, how to perform the P4DM and conclusion. The P4DM was produced, which provide the development direction of PIM in the future, and also provide the new ideas for PetroChina in the field of technology and management. (author)

  11. The teaching of nursing management in undergraduate: an integrative review

    Directory of Open Access Journals (Sweden)

    Mara Solange Gomes Dellaroza

    2015-03-01

    Full Text Available The study aims to identify the dynamics of teaching management in nursing degree. It is an integrative literature review with research conducted in the following online database platforms: SciELO, Medline, Lilacs and BDENF. The keywords used in the study were: competency-based education, professional competence, education, nursing, organization and administration, management, nursing, educational assessment, organization of management services, management of professional practice and education. All articles published in the last 10 years which answered the question presented to approach the teaching of nursing management in Brazil, published in any language were included. Those that were not presented in full text were excluded. Of the 1432 studies identified after matching the keywords, only 8 were selected for answering objective of this review. From these results, three related themes emerged: the teaching plans, workload and program content; methodologies of teaching and learning in nursing management; challenges faced in developing the teaching of nursing management.

  12. Integrated forest management to prevent wildfires under Mediterranean environments

    Directory of Open Access Journals (Sweden)

    Piermaria Corona

    2015-02-01

    Full Text Available This review presents a multidisciplinary framework for integrating the ecological, regulatory, procedural and technical aspects of forest management for fires prevention under Mediterranean environments. The aims are to: i provide a foreground of wildfire scenario; ii illustrate the theoretical background of forest fuel management; iii describe the available fuel management techniques and mechanical operations for fire prevention in forest and wildland-urban interfaces, with exemplification of case-studies; iv allocate fire prevention activities under the hierarchy of forest planning. The review is conceived as an outline commentary discussion targeted to professionals, technicians and government personnel involved in forestry and environmental management.

  13. Increased malaria transmission around irrigation schemes in Ethiopia and the potential of canal water management for malaria vector control.

    Science.gov (United States)

    Kibret, Solomon; Wilson, G Glenn; Tekie, Habte; Petros, Beyene

    2014-09-13

    Irrigation schemes have been blamed for the increase in malaria in many parts of sub-Saharan Africa. However, proper water management could help mitigate malaria around irrigation schemes in this region. This study investigates the link between irrigation and malaria in Central Ethiopia. Larval and adult mosquitoes were collected fortnightly between November 2009 and October 2010 from two irrigated and two non-irrigated (control) villages in the Ziway area, Central Ethiopia. Daily canal water releases were recorded during the study period and bi-weekly correlation analysis was done to determine relationships between canal water releases and larval/adult vector densities. Blood meal sources (bovine vs human) and malaria sporozoite infection were tested using enzyme-linked immunosorbent assay (ELISA). Monthly malaria data were also collected from central health centre of the study villages. Monthly malaria incidence was over six-fold higher in the irrigated villages than the non-irrigated villages. The number of anopheline breeding habitats was 3.6 times higher in the irrigated villages than the non-irrigated villages and the most common Anopheles mosquito breeding habitats were waterlogged field puddles, leakage pools from irrigation canals and poorly functioning irrigation canals. Larval and adult anopheline densities were seven- and nine-fold higher in the irrigated villages than in the non-irrigated villages, respectively, during the study period. Anopheles arabiensis was the predominant species in the study area. Plasmodium falciparum sporozoite rates of An. arabiensis and Anopheles pharoensis were significantly higher in the irrigated villages than the non-irrigated villages. The annual entomological inoculation rate (EIR) calculated for the irrigated and non-irrigated villages were 34.8 and 0.25 P. falciparum infective bites per person per year, respectively. A strong positive correlation was found between bi-weekly anopheline larval density and canal water

  14. Intellectual capital management as the integral part of enterprise’s management

    OpenAIRE

    Аліна Олександрівна Осаул

    2016-01-01

    The main levels of the enterprise’s intellectual capital management are analyzed in the article. The distinctive peculiarities of the enterprise’s intellectual capital management are mentioned. Goals and benefits of the intellectual management system are determined. The ways of their improvement are pointed out. Implicit and explicit knowledge as an important integral intellectual capital resources are divided and characterized

  15. Integrating fire management into land management planning for west-side forests

    Science.gov (United States)

    Peter D. Teensma

    1996-01-01

    Fire management's integration into land management planning is critical to the successful management of nearly all wildland ecosystems, including westside forests, which lie west of the Cascade crest in Oregon and the northern coastal ranges in California. Restoration and maintenance of fire as an ecosystem process is critical to retention of biological diversity...

  16. Total Quality Management and Organizational Behavior Management: An Integration for Continual Improvement.

    Science.gov (United States)

    Mawhinney, Thomas C.

    1992-01-01

    The history and main features of organizational behavior management (OBM) are compared and integrated with those of total quality management (TQM), with emphasis on W.E. Deming's 14 points and OBM's operant-based approach to performance management. Interventions combining OBM, TQM, and statistical process control are recommended. (DB)

  17. Asset management: integrated software optimizes production performance

    Energy Technology Data Exchange (ETDEWEB)

    Polczer, S.

    1998-06-01

    Two new multi-dimensional databases, which expand the `row and column` concept of spreadsheets into multiple categories of data called dimensions, are described. These integrated software packages provide the foundation for industry players such as Poco Petroleum Ltd and Numac Energy Inc to gain a competitive advantage, by overhauling their respective data collection and retrieval systems to allow for timely cost analysis and financial reporting. Energy Warehouse, an on-line analytical processing product marketed by SysGold Ltd, is one of the software products described. It gathers various sources of information, allows advanced searches and generates reports previously unavailable in other conventional financial accounting systems. The second product discussed - the Canadian Upstream Energy System (CUES) - is an on-line analytical processing system developed by Oracle Corporation and Calgary-based Applied Terravision Systems (ATS) Inc. CUES combines Oracle`s universal data server and software development tools with ATS`s upstream financial, land, geotechnical and production applications. The software also allows for optimization of facilities, analysis of production efficiencies and comparison of performance against industry standards.

  18. SYSTEMS FOR IMPROVEMENT OF BUSINESS INTEGRATED MANAGEMENT PROCESSES IN PORTS

    Directory of Open Access Journals (Sweden)

    Pavle Popovic

    2017-03-01

    Full Text Available Based on test results obtained so far, the objective relating to modern scientific methods and approaches has been defined with the intention to develop model which defines new management system integration model, by adopting necessary practical terms of real systems that most frequently circulate in maritime practice in the field of integrated management systems (IMS in terms of safety and security of vessels and ports. The subject of research is maritime, particularly port services, by way of defining internal and external advantages through adopting integrated management systems. The research will be conducted through theoretical and applied assessments of case study analyses using example of the Port of Kotor H.Co.

  19. THE MANAGEMENT ACCOUNTING TOOLS AND THE INTEGRATED REPORTING

    Directory of Open Access Journals (Sweden)

    Gabriel JINGA

    2015-04-01

    Full Text Available During the recent years the stakeholders are asking for other pieces of information to be published along with the financial one, such as risk reporting, intangibles, social and environmental accounting. The type of corporate reporting which incorporates the elements enumerated above is the integrated reporting. In this article, we argue that the information disclosed in the integrated reports is prepared by the management accounting, not only by the financial accounting. Thus, we search for the management accounting tools which are used by the companies which prepare integrated reports. In order to do this, we analytically reviewed all the reports available on the website of a selected company. Our results show that the company is using most of the management accounting tools mentioned in the literature review part.

  20. Managing Key Risks in Post-Merger IS Integration

    DEFF Research Database (Denmark)

    Alaranta, Mar; Mathiassen, L

    2014-01-01

    Mergers and acquisitions (M&A) require organizations to blend together different information system (IS) configurations. Unfortunately, less than 50 percent of M&A's achieve their goals, with IS integration being a major problem. Here, the authors offer a framework to help managers prepare for......, analyze, and mitigate risks during post-merger IS integration. They identify key risks relating to IS integration content, process, and context, and present five strategies for mitigating those risks. Their framework aims to help managers proactively reduce the impact of adverse events. Adopting...... the framework supported by their templates is straightforward and the time and resources required are minimal. When properly executed, adoption increases the likelihood of successful merger outcomes; the framework is thus a valuable addition to the management tool box and can be applied in collaboration...

  1. IMPLEMENTATION OF INTEGRAL SYSTEM OF QUALITY MANAGEMENT IN TOURISM

    Directory of Open Access Journals (Sweden)

    Vidoje Vujic

    2007-12-01

    Full Text Available Theory and practice have corroborated the need and usefulness of an integral approach to quality management in tourist destinations, since the destination and its touristic offer define a number of disparate participants and interested parties. An integral system of quality management is one of the models of touristic management that with the implementation of contemporary principles strives to achieve business excellence and competitory advantage. The paper determines and projects the need and importance of implementing an integral system and accordingly seeks to form a model for its development. By studying the oneness of the whole we have established the dependence and firm connections between particular norms and elements, and by analyzing them in this paper we describe the structure and associated characteristics of the whole.

  2. Integrated Constructed Wetlands (ICW) for livestock wastewater management.

    Science.gov (United States)

    Harrington, Rory; McInnes, Robert

    2009-11-01

    Social, economic and environmental coherence is sought in the management of livestock wastewater. Wetlands facilitate the biogeochemical processes that exploit livestock wastewater and provide opportunities to achieve such coherence and also to deliver on a range of ecosystem services. The Integrated Constructed Wetland (ICW) concept integrates three inextricably linked objectives: water quantity and quality management, landscape-fit to improve aesthetic site values and enhanced biodiversity. The synergies derived from this explicit integration allow one of the key challenges for livestock management to be addressed. An example utilizing twelve ICW systems from a catchment on the south coast of Ireland demonstrates that over an eight year period mean reduction of total and soluble phosphorus (molybdate reactive phosphorus) exceeded 95% and the mean removal of ammonium-N exceeded 98%. This paper reviews evidence regarding the capacity of ICWs to provide a coherent and sustainable alternative to conventional systems.

  3. Environmental Management Integration Project/Mixed Waste Focus Area Partnership

    International Nuclear Information System (INIS)

    Gombert, D.; Kristofferson, K.; Cole, L.

    1999-01-01

    On January 16, 1998, the Assistant Secretary for the Environmental Management (EM) Program at the Department of Energy, issued DOE-Idaho the Program Integration and Systems Engineering Guidance for Fiscal Year 1998, herein called Guidance, which directed that program integration tasks be performed for all EM program areas. This guidance directed the EM Integration team, as part of the Task 1, to develop baseline waste and material disposition maps which are owned by the site Project Baseline Summary (PBS) manager. With these baselines in place Task 2 gave direction to link Science and Technology activities to the waste and material stream supported by that technology. This linkage of EM Program needs with the OST activities supports the DOE goal of maximizing cleanup at DOE sites by 2006 and provides a defensible science and technology program. Additionally, this linkage is a valuable tool in the integration of the waste and material disposition efforts for the DOE complex

  4. Integrating environment health and safety management at Petro-Canada

    International Nuclear Information System (INIS)

    Raymond, G.

    1993-01-01

    Petro-Canada has developed a tool to integrate, measure, and improve its management systems of environment, health, and safety (EH ampersand S). This tool, called the Total Loss Management System, is described in the areas of general management issues, policies and procedures, evaluations, organization, stewardship, issue management, and performance measures. Petro-Canada's policies on occupational health and safety are consistent with its environmental policy, being structured in the same way. An integrated audit system is used to cover health, safety, industrial hygiene, reliability, environment, and risk management. EH ampersand S matters are integrated at the corporate level in a separate department. Regional divisions review EH ampersand S performance every month, incidents are discussed, and preventive measures are taken as necessary. Regional performances are combined every quarter for ultimate presentation to the Petro-Canada board. New or emerging issues that may affect divisions are assigned an issue sponsor, a member of divisional management who makes sure the issue receives the resources necessary to study and define its impact. Examples of issues include soil contamination, process hazard management, and benzene exposure limits. Performance measures flow from the corporate environment and occupational health and safety policies, and come in two types: those that measure activities to improve performance and those that measure the outcome of the activities

  5. Genetic engineering in Actinoplanes sp. SE50/110 - development of an intergeneric conjugation system for the introduction of actinophage-based integrative vectors.

    Science.gov (United States)

    Gren, Tetiana; Ortseifen, Vera; Wibberg, Daniel; Schneiker-Bekel, Susanne; Bednarz, Hanna; Niehaus, Karsten; Zemke, Till; Persicke, Marcus; Pühler, Alfred; Kalinowski, Jörn

    2016-08-20

    The α-glucosidase inhibitor acarbose is used for treatment of diabetes mellitus type II, and is manufactured industrially with overproducing derivatives of Actinoplanes sp. SE50/110, reportedly obtained by conventional mutagenesis. Despite of high industrial significance, only limited information exists regarding acarbose metabolism, function and regulation of these processes, due to the absence of proper genetic engineering methods and tools developed for this strain. Here, a basic toolkit for genetic engineering of Actinoplanes sp. SE50/110 was developed, comprising a standardized protocol for a DNA transfer through Escherichia coli-Actinoplanes intergeneric conjugation and applied for the transfer of ϕC31, ϕBT1 and VWB actinophage-based integrative vectors. Integration sites, occurring once per genome for all vectors, were sequenced and characterized for the first time in Actinoplanes sp. SE50/110. Notably, in case of ϕC31 based vector pSET152, the integration site is highly conserved, while for ϕBT1 and the VWB based vectors pRT801 and pSOK804, respectively, no sequence similarities to those in other bacteria were detected. The studied plasmids were proven to be stable and neutral with respect to strain morphology and acarbose production, enabling future use for genetic manipulations of Actinoplanes sp. SE50/110. To further broaden the spectrum of available tools, a GUS reporter system, based on the pSET152 derived vector, was also established in Actinoplanes sp. SE50/110. Copyright © 2016 Elsevier B.V. All rights reserved.

  6. Integrated risk management for business survival

    International Nuclear Information System (INIS)

    Piatt, J.A.

    1992-06-01

    During the recent recession, many businesses have had to take severe measures to cut costs. The Department of Defense has also been faced with the need to cut costs to offset the expense of the Gulf War and a shrinking budget due to the fall of communism around the world. With the collapse of the Warsaw Pact and dissolution of the Soviet Union, there has been an increasing demand to reduce the defense budget to provide the so-called ''peace dividend'' to deal with social and economic problems at home. President Bush's State of the Union Message in February 1992 called for deeper cuts than the 25% previously anticipated. It also called for these cuts to occur sooner than expected with $50 billion in defense cuts anticipated over the fiscal 1992--1997 period. The Department of Defense plan for force resizing calls for 25-30% reductions over time. This report discusses how the department of defense is trying to deal with the management of this crisis

  7. Integration of Biosafety into Core Facility Management

    Science.gov (United States)

    Fontes, Benjamin

    2013-01-01

    This presentation will discuss the implementation of biosafety policies for small, medium and large core laboratories with primary shared objectives of ensuring the control of biohazards to protect core facility operators and assure conformity with applicable state and federal policies, standards and guidelines. Of paramount importance is the educational process to inform core laboratories of biosafety principles and policies and to illustrate the technology and process pathways of the core laboratory for biosafety professionals. Elevating awareness of biohazards and the biosafety regulatory landscape among core facility operators is essential for the establishment of a framework for both project and material risk assessment. The goal of the biohazard risk assessment process is to identify the biohazard risk management parameters to conduct the procedure safely and in compliance with applicable regulations. An evaluation of the containment, protective equipment and work practices for the procedure for the level of risk identified is facilitated by the establishment of a core facility registration form for work with biohazards and other biological materials with potential risk. The final step in the biocontainment process is the assumption of Principal Investigator role with full responsibility for the structure of the site-specific biosafety program plan by core facility leadership. The presentation will provide example biohazard protocol reviews and accompanying containment measures for core laboratories at Yale University.

  8. Commercial Aircraft Integrated Vehicle Health Management Study

    Science.gov (United States)

    Reveley, Mary S.; Briggs, Jeffrey L.; Evans, Joni K.; Jones, Sharon Monica; Kurtoglu, Tolga; Leone, Karen M.; Sandifer, Carl E.; Thomas, Megan A.

    2010-01-01

    Statistical data and literature from academia, industry, and other government agencies were reviewed and analyzed to establish requirements for fixture work in detection, diagnosis, prognosis, and mitigation for IVHM related hardware and software. Around 15 to 20 percent of commercial aircraft accidents between 1988 and 2003 involved inalftfnctions or failures of some aircraft system or component. Engine and landing gear failures/malfunctions dominate both accidents and incidents. The IVI vl Project research technologies were found to map to the Joint Planning and Development Office's National Research and Development Plan (RDP) as well as the Safety Working Group's National Aviation Safety Strategic. Plan (NASSP). Future directions in Aviation Technology as related to IVHlvl were identified by reviewing papers from three conferences across a five year time span. A total of twenty-one trend groups in propulsion, aeronautics and aircraft categories were compiled. Current and ftiture directions of IVHM related technologies were gathered and classified according to eight categories: measurement and inspection, sensors, sensor management, detection, component and subsystem monitoring, diagnosis, prognosis, and mitigation.

  9. Integrated risk management for business survival

    Energy Technology Data Exchange (ETDEWEB)

    Piatt, J.A.

    1992-06-01

    During the recent recession, many businesses have had to take severe measures to cut costs. The Department of Defense has also been faced with the need to cut costs to offset the expense of the Gulf War and a shrinking budget due to the fall of communism around the world. With the collapse of the Warsaw Pact and dissolution of the Soviet Union, there has been an increasing demand to reduce the defense budget to provide the so-called peace dividend'' to deal with social and economic problems at home. President Bush's State of the Union Message in February 1992 called for deeper cuts than the 25% previously anticipated. It also called for these cuts to occur sooner than expected with $50 billion in defense cuts anticipated over the fiscal 1992--1997 period. The Department of Defense plan for force resizing calls for 25-30% reductions over time. This report discusses how the department of defense is trying to deal with the management of this crisis.

  10. Integrated risk management for business survival

    Energy Technology Data Exchange (ETDEWEB)

    Piatt, J.A.

    1992-06-01

    During the recent recession, many businesses have had to take severe measures to cut costs. The Department of Defense has also been faced with the need to cut costs to offset the expense of the Gulf War and a shrinking budget due to the fall of communism around the world. With the collapse of the Warsaw Pact and dissolution of the Soviet Union, there has been an increasing demand to reduce the defense budget to provide the so-called ``peace dividend`` to deal with social and economic problems at home. President Bush`s State of the Union Message in February 1992 called for deeper cuts than the 25% previously anticipated. It also called for these cuts to occur sooner than expected with $50 billion in defense cuts anticipated over the fiscal 1992--1997 period. The Department of Defense plan for force resizing calls for 25-30% reductions over time. This report discusses how the department of defense is trying to deal with the management of this crisis.

  11. Regional Integrated Silvopastoral Approaches to Ecosystem Management Project

    OpenAIRE

    CIPAV (Centre For Research on Sustainable Agricultural Production Systems); CATIE (Centro Agronomico Tropical de Investigacion y Ensenanza); NITLAPAN

    2007-01-01

    Metadata only record The Regional Integrated Silvopastoral Approaches to Ecosystem Management Project introduces the payment for environmental services approach to silvopastoral farmers in Colombia, Costa Rica, and Nicaragua. The objectives of the project are to "demonstrate and measure a) the effects the introduction of payment incentives for environmental services to farmers on their adoption of integrated silvopastoral farming systems in degraded pasture lands; and b) the resulting impr...

  12. Science of Integrated Approaches to Natural Resources Management

    Science.gov (United States)

    Tengberg, Anna; Valencia, Sandra

    2017-04-01

    To meet multiple environmental objectives, integrated programming is becoming increasingly important for the Global Environmental Facility (GEF), the financial mechanism of the multilateral environmental agreements, including the United Nations Convention to Combat Desertification (UNCCD). Integration of multiple environmental, social and economic objectives also contributes to the achievement of the Sustainable Development Goals (SDGs) in a timely and cost-effective way. However, integration is often not well defined. This paper therefore focuses on identifying key aspects of integration and assessing their implementation in natural resources management (NRM) projects. To that end, we draw on systems thinking literature, and carry out an analysis of a random sample of GEF integrated projects and in-depth case studies demonstrating lessons learned and good practices in addressing land degradation and other NRM challenges. We identify numerous challenges and opportunities of integrated approaches that need to be addressed in order to maximise the catalytic impact of the GEF during problem diagnosis, project design, implementation and governance. We highlight the need for projects to identify clearer system boundaries and main feedback mechanisms within those boundaries, in order to effectively address drivers of environmental change. We propose a theory of change for Integrated Natural Resources Management (INRM) projects, where short-term environmental and socio-economic benefits will first accrue at the local level. Implementation of improved INRM technologies and practices at the local level can be extended through spatial planning, strengthening of innovation systems, and financing and incentive mechanisms at the watershed and/or landscape/seascape level to sustain and enhance ecosystem services at larger scales and longer time spans. We conclude that the evolving scientific understanding of factors influencing social, technical and institutional innovations and

  13. Temporo-spatial distribution of insecticide-resistance in Indian malaria vectors in the last quarter-century: Need for regular resistance monitoring and management.

    Science.gov (United States)

    Raghavendra, Kamaraju; Velamuri, Poonam Sharma; Verma, Vaishali; Elamathi, Natarajan; Barik, Tapan Kumar; Bhatt, Rajendra Mohan; Dash, Aditya Prasad

    2017-01-01

    The Indian vector control programme similar to other programmes in the world is still reliant on chemical insecticides. Anopheles culicifacies is the major vector out of six primary malaria vectors in India and alone contributes about 2/3 malaria cases annually; and per se its control is actually control of malaria in India. For effective management of vectors, current information on their susceptibility status to different insecticides is essential. In this review, an attempt was made to compile and present the available data on the susceptibility status of different malaria vector species in India from the last 2.5 decades. Literature search was conducted by different means mainly web and library search; susceptibility data was collated from 62 sources for the nine malaria vector species from 145 districts in 21 states and two union territories between 1991 and 2016. Interpretation of the susceptibility/resistance status was made on basis of the recent WHO criteria. Comprehensive analysis of the data indicated that An. culicifacies, a major vector species was resistant to at least one insecticide in 70% (101/145) of the districts. It was reported mostly resistant to DDT and malathion whereas, its resistant status against deltamethrin varied across the districts. The major threat for the malaria control programmes is multiple-insecticide-resistance in An. culicifacies which needs immediate attention for resistance management in order to sustain the gains achieved so far, as the programmes have targeted malaria elimination by 2030.

  14. An integrated reliability management system for nuclear power plants

    International Nuclear Information System (INIS)

    Kimura, T.; Shimokawa, H.; Matsushima, H.

    1998-01-01

    The responsibility in the nuclear field of the Government, utilities and manufactures has increased in the past years due to the need of stable operation and great reliability of nuclear power plants. The need to improve the reliability is not only for the new plants but also for those now running. So, several measures have been taken to improve reliability. In particular, the plant manufactures have developed a reliability management system for each phase (planning, construction, maintenance and operation) and these have been integrated as a unified system. This integrated reliability management system for nuclear power plants contains information about plant performance, failures and incidents which have occurred in the plants. (author)

  15. Integrating Environmental and Information Systems Management: An Enterprise Architecture Approach

    Science.gov (United States)

    Noran, Ovidiu

    Environmental responsibility is fast becoming an important aspect of strategic management as the reality of climate change settles in and relevant regulations are expected to tighten significantly in the near future. Many businesses react to this challenge by implementing environmental reporting and management systems. However, the environmental initiative is often not properly integrated in the overall business strategy and its information system (IS) and as a result the management does not have timely access to (appropriately aggregated) environmental information. This chapter argues for the benefit of integrating the environmental management (EM) project into the ongoing enterprise architecture (EA) initiative present in all successful companies. This is done by demonstrating how a reference architecture framework and a meta-methodology using EA artefacts can be used to co-design the EM system, the organisation and its IS in order to achieve a much needed synergy.

  16. Integrated tracking, classification, and sensor management theory and applications

    CERN Document Server

    Krishnamurthy, Vikram; Vo, Ba-Ngu

    2012-01-01

    A unique guide to the state of the art of tracking, classification, and sensor management. This book addresses the tremendous progress made over the last few decades in algorithm development and mathematical analysis for filtering, multi-target multi-sensor tracking, sensor management and control, and target classification. It provides for the first time an integrated treatment of these advanced topics, complete with careful mathematical formulation, clear description of the theory, and real-world applications. Written by experts in the field, Integrated Tracking, Classification, and Sensor Management provides readers with easy access to key Bayesian modeling and filtering methods, multi-target tracking approaches, target classification procedures, and large scale sensor management problem-solving techniques.

  17. Integrated Management System – Scope, Possibilities And Methodology

    Directory of Open Access Journals (Sweden)

    Čekanová Katarína

    2015-06-01

    Full Text Available Organizations are becoming more aware of the importance of integrated management systems (IMS. Interest in this subject indicates that IMS are seen as “management systems of the future”. Based on this, the aim of this articles characterizes the possibility of building IMS through the identification of common elements and specific requirements in accordance with the ISO 9001, ISO 14001 and OHSAS 18001 professional references. Part of the article is the methodology of building IMS in the organization.

  18. Technology and diabetes self-management: An integrative review

    OpenAIRE

    Hunt, Caralise W

    2015-01-01

    Technology can be used to supplement healthcare provider diabetes care by providing both educational and motivational support. Education can be provided using technology allowing patients to learn new practices and routines related to diabetes management. Technology can support daily diabetes self-management activities including blood glucose monitoring, exercising, healthy eating, taking medication, monitoring for complications, and problem-solving. This article describes an integrative revi...

  19. ACCOUNTANT'S WARNING REGARDING THE LACK OF MANAGEMENT INTEGRITY

    Directory of Open Access Journals (Sweden)

    SORIN ADRIAN ACHIM

    2011-04-01

    Full Text Available This article highlights the challenges faced by accountants when they find that the integrity of company management is poor. The main problem is in relation with the accountants’ fear, mostly: suffering some repercussions from the disclosure of such information. Also, this article aims to emphasize the danger brought by covering and concealing incriminating information against the management; but also, how accountants could expose this information in such a way that they would not suffer, under no circumstances from such disclosures.

  20. Integration mockup and process material management system

    Science.gov (United States)

    Verble, Adas James, Jr.

    1992-01-01

    Work to define and develop a full scale Space Station Freedom (SSF) mockup with the flexibility to evolve into future designs, to validate techniques for maintenance and logistics and verify human task allocations and support trade studies is described. This work began in early 1985 and ended in August, 1991. The mockups are presently being used at MSFC in Building 4755 as a technology and design testbed, as well as for public display. Micro Craft also began work on the Process Material Management System (PMMS) under this contract. The PMMS simulator was a sealed enclosure for testing to identify liquids, gaseous, particulate samples, and specimen including, urine, waste water, condensate, hazardous gases, surrogate gasses, liquids, and solids. The SSF would require many trade studies to validate techniques for maintenance and logistics and verify system task allocations; it was necessary to develop a full scale mockup which would be representative of current SSF design with the ease of changing those designs as the SSF design evolved and changed. The tasks defined for Micro Craft were to provide the personnel, services, tools, and materials for the SSF mockup which would consist of four modules, nodes, interior components, and part task mockups of MSFC responsible engineering systems. This included the Engineering Control and Life Support Systems (ECLSS) testbed. For the initial study, the mockups were low fidelity, soft mockups of graphics art bottle, and other low cost materials, which evolved into higher fidelity mockups as the R&D design evolved, by modifying or rebuilding, an important cost saving factor in the design process. We designed, fabricated, and maintained the full size mockup shells and support stands. The shells consisted of cylinders, end cones, rings, longerons, docking ports, crew airlocks, and windows. The ECLSS required a heavier cylinder to support the ECLSS systems test program. Details of this activity will be covered. Support stands were