WorldWideScience

Sample records for integrated tol2 element

  1. Genome-wide analysis of Tol2 transposon reintegration in zebrafish

    Directory of Open Access Journals (Sweden)

    Parinov Sergey

    2009-09-01

    Full Text Available Abstract Background Tol2, a member of the hAT family of transposons, has become a useful tool for genetic manipulation of model animals, but information about its interactions with vertebrate genomes is still limited. Furthermore, published reports on Tol2 have mainly been based on random integration of the transposon system after co-injection of a plasmid DNA harboring the transposon and a transposase mRNA. It is important to understand how Tol2 would behave upon activation after integration into the genome. Results We performed a large-scale enhancer trap (ET screen and generated 338 insertions of the Tol2 transposon-based ET cassette into the zebrafish genome. These insertions were generated by remobilizing the transposon from two different donor sites in two transgenic lines. We found that 39% of Tol2 insertions occurred in transcription units, mostly into introns. Analysis of the transposon target sites revealed no strict specificity at the DNA sequence level. However, Tol2 was prone to target AT-rich regions with weak palindromic consensus sequences centered at the insertion site. Conclusion Our systematic analysis of sequential remobilizations of the Tol2 transposon from two independent sites within a vertebrate genome has revealed properties such as a tendency to integrate into transcription units and into AT-rich palindrome-like sequences. This information will influence the development of various applications involving DNA transposons and Tol2 in particular.

  2. Genome-wide analysis of Tol2 transposon reintegration in zebrafish.

    Science.gov (United States)

    Kondrychyn, Igor; Garcia-Lecea, Marta; Emelyanov, Alexander; Parinov, Sergey; Korzh, Vladimir

    2009-09-08

    Tol2, a member of the hAT family of transposons, has become a useful tool for genetic manipulation of model animals, but information about its interactions with vertebrate genomes is still limited. Furthermore, published reports on Tol2 have mainly been based on random integration of the transposon system after co-injection of a plasmid DNA harboring the transposon and a transposase mRNA. It is important to understand how Tol2 would behave upon activation after integration into the genome. We performed a large-scale enhancer trap (ET) screen and generated 338 insertions of the Tol2 transposon-based ET cassette into the zebrafish genome. These insertions were generated by remobilizing the transposon from two different donor sites in two transgenic lines. We found that 39% of Tol2 insertions occurred in transcription units, mostly into introns. Analysis of the transposon target sites revealed no strict specificity at the DNA sequence level. However, Tol2 was prone to target AT-rich regions with weak palindromic consensus sequences centered at the insertion site. Our systematic analysis of sequential remobilizations of the Tol2 transposon from two independent sites within a vertebrate genome has revealed properties such as a tendency to integrate into transcription units and into AT-rich palindrome-like sequences. This information will influence the development of various applications involving DNA transposons and Tol2 in particular.

  3. Contemporary zebrafish transgenesis with Tol2 and application for Cre/lox recombination experiments.

    Science.gov (United States)

    Felker, A; Mosimann, C

    2016-01-01

    Spatiotemporal transgene regulation by transgenic DNA recombinases is a central tool for reverse genetics in multicellular organisms, with excellent applications for misexpression and lineage tracing experiments. One of the most widespread technologies for this purpose is Cre recombinase-controlled lox site recombination that is attracting increasing interest in the zebrafish field. Tol2-mediated zebrafish transgenesis provides a stable platform to integrate lox cassette transgenes, while the amenability of the zebrafish embryo to drug treatments makes the model an ideal candidate for tamoxifen-inducible CreERT2 experiments. In addition, advanced transgenesis technologies such as phiC31 or CRISPR-Cas9-based knock-ins are even further promoting zebrafish transgenesis for Cre/lox applications. In this chapter, we will first introduce the basics of Cre/lox methodology, CreERT2 regulation by tamoxifen, as well as the utility of Tol2 and other contemporary transgenesis techniques for Cre/lox experiments. We will then outline in detail practical experimental steps for efficient transgenesis toward the creation of single-insertion transgenes and will introduce protocols for 4-hydroxytamoxifen-mediated CreERT2 induction to perform spatiotemporal lox transgene regulation experiments in zebrafish embryos. Last, we will discuss advanced experimental applications of Cre/lox beyond traditional lineage tracing approaches. Copyright © 2016 Elsevier Inc. All rights reserved.

  4. Tol2 transposon-mediated transgenesis in the Midas cichlid (Amphilophus citrinellus) - towards understanding gene function and regulatory evolution in an ecological model system for rapid phenotypic diversification.

    Science.gov (United States)

    Kratochwil, Claudius F; Sefton, Maggie M; Liang, Yipeng; Meyer, Axel

    2017-11-23

    The Midas cichlid species complex (Amphilophus spp.) is widely known among evolutionary biologists as a model system for sympatric speciation and adaptive phenotypic divergence within extremely short periods of time (a few hundred generations). The repeated parallel evolution of adaptive phenotypes in this radiation, combined with their near genetic identity, makes them an excellent model for studying phenotypic diversification. While many ecological and evolutionary studies have been performed on Midas cichlids, the molecular basis of specific phenotypes, particularly adaptations, and their underlying coding and cis-regulatory changes have not yet been studied thoroughly. For the first time in any New World cichlid, we use Tol2 transposon-mediated transgenesis in the Midas cichlid (Amphilophus citrinellus). By adapting existing microinjection protocols, we established an effective protocol for transgenesis in Midas cichlids. Embryos were injected with a Tol2 plasmid construct that drives enhanced green fluorescent protein (eGFP) expression under the control of the ubiquitin promoter. The transgene was successfully integrated into the germline, driving strong ubiquitous expression of eGFP in the first transgenic Midas cichlid line. Additionally, we show transient expression of two further transgenic constructs, ubiquitin::tdTomato and mitfa::eGFP. Transgenesis in Midas cichlids will facilitate further investigation of the genetic basis of species-specific traits, many of which are adaptations. Transgenesis is a versatile tool not only for studying regulatory elements such as promoters and enhancers, but also for testing gene function through overexpression of allelic gene variants. As such, it is an important first step in establishing the Midas cichlid as a powerful model for studying adaptive coding and non-coding changes in an ecological and evolutionary context.

  5. Integral nuclear fuel element assembly

    International Nuclear Information System (INIS)

    Schluderberg, D. C.

    1985-01-01

    An integral nuclear fuel element assembly utilizes longitudinally finned fuel pins. The continuous or interrupted fins of the fuel pins are brazed to fins of juxtaposed fuel pins or directly to the juxtaposed fuel pins or both. The integrally brazed fuel assembly is designed to satisfy the thermal and hydraulic requirements of a fuel assembly lattice having moderator to fuel atom ratios required to achieve high conversion and breeding ratios

  6. Division algebras with integral elements

    International Nuclear Information System (INIS)

    Koca, M.; Ozdes, N.

    1988-06-01

    Pairing two elements of a given division algebra furnished with a multiplication rule leads to an algebra of higher dimension restricted by 8. This fact is used to obtain the roots of SO(4) and SP(2) from the roots ±1 of SU(2) and the weights ±1/2 of its spinor representation. The root lattice of SO(8) described by 24 integral quaternions are obtained by pairing two sets of roots of SP(2). The root system of F 4 is constructed in terms of 24 integral and 24 ''half-integral'' quaternions. The root lattice of E 8 expressed as 240 integral octonions are obtained by pairing two sets of roots of F 4 . 24 integral quaternions of SO(8) forming a discrete subgroup of SU(2) is shown to be the automorphism group of the root lattices of SO(8), F 4 and E 8 . The roots of maximal subgroups SO(16), E 7 XSU(2), E 6 XSU(3), SU(9) and SU(5)XSU(5) of E 8 are identified with a simple method. Subsets of the discrete subgroup of SU(2) leaving maximal subgroups of E 8 are obtained. Constructions of E 8 root lattice with integral octonions in 7 distinct ways are made. Magic square of integral lattices of Goddard, Nahm, Olive, Ruegg and Schwimmer are derived. Possible physical applications are suggested. (author). 16 refs, 6 figs, 5 tabs

  7. Genome-wide target profiling of piggyBac and Tol2 in HEK 293: pros and cons for gene discovery and gene therapy

    Science.gov (United States)

    2011-01-01

    Background DNA transposons have emerged as indispensible tools for manipulating vertebrate genomes with applications ranging from insertional mutagenesis and transgenesis to gene therapy. To fully explore the potential of two highly active DNA transposons, piggyBac and Tol2, as mammalian genetic tools, we have conducted a side-by-side comparison of the two transposon systems in the same setting to evaluate their advantages and disadvantages for use in gene therapy and gene discovery. Results We have observed that (1) the Tol2 transposase (but not piggyBac) is highly sensitive to molecular engineering; (2) the piggyBac donor with only the 40 bp 3'-and 67 bp 5'-terminal repeat domain is sufficient for effective transposition; and (3) a small amount of piggyBac transposases results in robust transposition suggesting the piggyBac transpospase is highly active. Performing genome-wide target profiling on data sets obtained by retrieving chromosomal targeting sequences from individual clones, we have identified several piggyBac and Tol2 hotspots and observed that (4) piggyBac and Tol2 display a clear difference in targeting preferences in the human genome. Finally, we have observed that (5) only sites with a particular sequence context can be targeted by either piggyBac or Tol2. Conclusions The non-overlapping targeting preference of piggyBac and Tol2 makes them complementary research tools for manipulating mammalian genomes. PiggyBac is the most promising transposon-based vector system for achieving site-specific targeting of therapeutic genes due to the flexibility of its transposase for being molecularly engineered. Insights from this study will provide a basis for engineering piggyBac transposases to achieve site-specific therapeutic gene targeting. PMID:21447194

  8. Six elements of integrated primary healthcare.

    Science.gov (United States)

    Brown, Lynsey J; Oliver-Baxter, Jodie

    2016-03-01

    Integrated care has the potential to deliver efficiencies and improvements in patient experiences and health outcomes. Efforts towards integrated care, especially at the primary and community health levels, have increasingly been under focus, both nationally and internationally. In Australia, regional integration is a priority, and integration of care is a task for meso-level organisations such as Primary Health Networks (PHNs). This paper seeks to provide a list of elements and questions for consideration by organisations working across primary healthcare settings, looking to enact and improve the delivery of integrated care. Six elements that consistently emerged during the development of a series of rapid reviews on integrated primary healthcare in Australia are presented in this paper. The elements identified are context, governance and leadership, infrastructure, financing, engagement, and communication. They offer a starting point for reflection in the planning and practices of organisations in their drive for continuous improvements in integrated care.

  9. The Tol2 transposon system mediates the genetic engineering of T-cells with CD19-specific chimeric antigen receptors for B-cell malignancies.

    Science.gov (United States)

    Tsukahara, T; Iwase, N; Kawakami, K; Iwasaki, M; Yamamoto, C; Ohmine, K; Uchibori, R; Teruya, T; Ido, H; Saga, Y; Urabe, M; Mizukami, H; Kume, A; Nakamura, M; Brentjens, R; Ozawa, K

    2015-02-01

    Engineered T-cell therapy using a CD19-specific chimeric antigen receptor (CD19-CAR) is a promising strategy for the treatment of advanced B-cell malignancies. Gene transfer of CARs to T-cells has widely relied on retroviral vectors, but transposon-based gene transfer has recently emerged as a suitable nonviral method to mediate stable transgene expression. The advantages of transposon vectors compared with viral vectors include their simplicity and cost-effectiveness. We used the Tol2 transposon system to stably transfer CD19-CAR into human T-cells. Normal human peripheral blood lymphocytes were co-nucleofected with the Tol2 transposon donor plasmid carrying CD19-CAR and the transposase expression plasmid and were selectively propagated on NIH3T3 cells expressing human CD19. Expanded CD3(+) T-cells with stable and high-level transgene expression (~95%) produced interferon-γ upon stimulation with CD19 and specifically lysed Raji cells, a CD19(+) human B-cell lymphoma cell line. Adoptive transfer of these T-cells suppressed tumor progression in Raji tumor-bearing Rag2(-/-)γc(-/-) immunodeficient mice compared with control mice. These results demonstrate that the Tol2 transposon system could be used to express CD19-CAR in genetically engineered T-cells for the treatment of refractory B-cell malignancies.

  10. Integrating Responsive Building Elements in Buildings

    DEFF Research Database (Denmark)

    Haase, Matthias; Amato, Alex; Heiselberg, Per

    2006-01-01

    energy strategies to develop guidelines and procedures for estimation of environmental performance of responsive building elements and integrated building concepts This paper introduces the ideas of this collaborative work and discusses its usefulness for Hong Kong and China. Special focus was put...

  11. Mixed Element Formulation for the Finite Element-Boundary Integral Method

    National Research Council Canada - National Science Library

    Meese, J; Kempel, L. C; Schneider, S. W

    2006-01-01

    A mixed element approach using right hexahedral elements and right prism elements for the finite element-boundary integral method is presented and discussed for the study of planar cavity-backed antennas...

  12. Integrating Environmentally Responsive Elements in Buildings

    DEFF Research Database (Denmark)

    Heiselberg, Per

    2006-01-01

    Significant improvement have been achieved on efficiency improvements of specific building elements like the building envelope and building equipment and services and whilst most building elements still offer opportunities for efficiency improvements, the greatest future potential lie with techno......Significant improvement have been achieved on efficiency improvements of specific building elements like the building envelope and building equipment and services and whilst most building elements still offer opportunities for efficiency improvements, the greatest future potential lie...

  13. Elements of Contemporary Integrated Science Curriculum: Impacts ...

    African Journals Online (AJOL)

    This paper acknowledged the vital roles played by integration of ideas and established the progress brought about when science is taught as a unified whole through knowledge integration which birthed integrated science as a subject in Nigerian school curriculum. The efforts of interest groups at regional, national and ...

  14. elements of contemporary integrated science curriculum

    African Journals Online (AJOL)

    both science and technology (Hurd, 1975). Discoveries in nature are made easier through integration of ideas, thoughts and concepts. To this end, science teaching in the modern world ought to be interdisciplinary, unified, society based and aspire above all to achieve scientific literacy (Arokoyu and Dike, 2009). These are.

  15. The Elements of Integration and Lebesgue Measure

    CERN Document Server

    Bartle, Robert G

    2011-01-01

    The Wiley Classics Library consists of selected books that have become recognized classics in their respective fields. With these new unabridged and inexpensive editions, Wiley hopes to extend the life of these important works by making them available to future generations of mathematicians and scientists. Currently available in the Series: T. W. Anderson The Statistical Analysis of Time Series T. S. Arthanari & Yadolah Dodge Mathematical Programming in Statistics Emil Artin Geometric Algebra Norman T. J. Bailey The Elements of Stochastic Processes with Applications to the Natural Sciences Rob

  16. Asynchronous variational integration using continuous assumed gradient elements.

    Science.gov (United States)

    Wolff, Sebastian; Bucher, Christian

    2013-03-01

    Asynchronous variational integration (AVI) is a tool which improves the numerical efficiency of explicit time stepping schemes when applied to finite element meshes with local spatial refinement. This is achieved by associating an individual time step length to each spatial domain. Furthermore, long-term stability is ensured by its variational structure. This article presents AVI in the context of finite elements based on a weakened weak form (W2) Liu (2009) [1], exemplified by continuous assumed gradient elements Wolff and Bucher (2011) [2]. The article presents the main ideas of the modified AVI, gives implementation notes and a recipe for estimating the critical time step.

  17. Elements of an advanced integrated operator control station

    International Nuclear Information System (INIS)

    Clarke, M.M.; Kreifeldt, J.G.

    1984-01-01

    One of the critical determinants of performance for any remotely operated maintenance system is the compatibility achieved between elements of the man/machine interface (e.g., master manipulator controller, controls, displays) and the human operator. In the remote control engineering task of the Consolidated Fuel Reprocessing Program, considerable attention has been devoted to optimizing the man/machine interface of the operator control station. This system must be considered an integral element of the overall maintenance work system which includes transporters, manipulators, remote viewing, and other parts. The control station must reflect the integration of the operator team, control/display panels, manipulator master controllers, and remote viewing monitors. Human factors principles and experimentation have been used in the development of an advanced integrated operator control station designed for the advance servomanipulator. Key features of this next-generation design are summarized in this presentation. 7 references, 4 figures

  18. Elements of an advanced integrated operator control station

    International Nuclear Information System (INIS)

    Clarke, M.M.; Kreifeldt, J.G.

    1984-01-01

    One of the critical determinants of peformance for any remotely operated maintenance system is the compatibility achieved between elements of the man/machine interface (e.g., master manipulator controller, controls, displays, etc.) and the human operator. In the Remote Control Engineering task of the Consolidated Fuel Reprocessing Program, considerable attention has been devoted to optimizing the man/machine interface of the operator control station. This system must be considered an integral element of the overall maintenance work system which includes transporters, manipulators, remote viewing, and other parts. The control station must reflect the integration of the operator team, control/display panels, manipulator master controllers, and remote viewing monitors. Human factors principles and experimentation have been used in the development of an advanced integrated operator control station designed for the advance servomanipulator. Key features of this next-generation design are summarized in this presentation. 7 references, 4 figures

  19. Integral finite element analysis of turntable bearing with flexible rings

    Science.gov (United States)

    Deng, Biao; Liu, Yunfei; Guo, Yuan; Tang, Shengjin; Su, Wenbin; Lei, Zhufeng; Wang, Pengcheng

    2018-03-01

    This paper suggests a method to calculate the internal load distribution and contact stress of the thrust angular contact ball turntable bearing by FEA. The influence of the stiffness of the bearing structure and the plastic deformation of contact area on the internal load distribution and contact stress of the bearing is considered. In this method, the load-deformation relationship of the rolling elements is determined by the finite element contact analysis of a single rolling element and the raceway. Based on this, the nonlinear contact between the rolling elements and the inner and outer ring raceways is same as a nonlinear compression spring and bearing integral finite element analysis model including support structure was established. The effects of structural deformation and plastic deformation on the built-in stress distribution of slewing bearing are investigated on basis of comparing the consequences of load distribution, inner and outer ring stress, contact stress and other finite element analysis results with the traditional bearing theory, which has guiding function for improving the design of slewing bearing.

  20. Social research design: framework for integrating philosophical and practical elements.

    Science.gov (United States)

    Cunningham, Kathryn Burns

    2014-09-01

    To provide and elucidate a comprehensible framework for the design of social research. An abundance of information exists concerning the process of designing social research. The overall message that can be gleaned is that numerable elements - both philosophical (ontological and epistemological assumptions and theoretical perspective) and practical (issue to be addressed, purpose, aims and research questions) - are influential in the process of selecting a research methodology and methods, and that these elements and their inter-relationships must be considered and explicated to ensure a coherent research design that enables well-founded and meaningful conclusions. There is a lack of guidance concerning the integration of practical and philosophical elements, hindering their consideration and explication. The author's PhD research into loneliness and cancer. This is a methodology paper. A guiding framework that incorporates all of the philosophical and practical elements influential in social research design is presented. The chronological and informative relationships between the elements are discussed. The framework presented can be used by social researchers to consider and explicate the practical and philosophical elements influential in the selection of a methodology and methods. It is hoped that the framework presented will aid social researchers with the design and the explication of the design of their research, thereby enhancing the credibility of their projects and enabling their research to establish well-founded and meaningful conclusions.

  1. Integration of element technology and system supporting thermonuclear fusion

    International Nuclear Information System (INIS)

    2003-01-01

    A special committee for integrated system technology survey on thermonuclear fusion (TNF) was begun on June, 1999, under an aim to generally summarize whole of shapes on technology to realize TNF reactor to summarize present state of every technologies and their positioning in whole of their TNF technology. On a base of survey of these recent informations, this report is comprehensively summarized for an integrated system technology on TNF. It has outlines on magnetic field enclosing method, outlines on inertia enclosing method, element technology supporting TNF, new power generation techniques, and ripple effects on TNF technology. (G.K.)

  2. Design Process for Integrated Concepts with Responsive Building Elements

    DEFF Research Database (Denmark)

    Aa, Van der A.; Heiselberg, Per

    2008-01-01

    An integrated building concept is a prerequisite to come to an energy efficient building with a good and healthy IAQ indoor comfort. A design process that defines the targets and boundary conditions in the very first stage of the design and guarantees them until the building is finished and used...... is needed. The hard question is however: how to make the right choice of the combination of individual measures from building components and building services elements. Within the framework of IEA-ECBCS Annex 44 research has been conducted about the design process for integrated building concepts...

  3. EMPIRICALLY DERIVED INTEGRATED STELLAR YIELDS OF Fe-PEAK ELEMENTS

    International Nuclear Information System (INIS)

    Henry, R. B. C.; Cowan, John J.; Sobeck, Jennifer

    2010-01-01

    We present here the initial results of a new study of massive star yields of Fe-peak elements. We have compiled from the literature a database of carefully determined solar neighborhood stellar abundances of seven iron-peak elements, Ti, V, Cr, Mn, Fe, Co, and Ni, and then plotted [X/Fe] versus [Fe/H] to study the trends as functions of metallicity. Chemical evolution models were then employed to force a fit to the observed trends by adjusting the input massive star metallicity-sensitive yields of Kobayashi et al. Our results suggest that yields of Ti, V, and Co are generally larger as well as anticorrelated with metallicity, in contrast to the Kobayashi et al. predictions. We also find the yields of Cr and Mn to be generally smaller and directly correlated with metallicity compared to the theoretical results. Our results for Ni are consistent with theory, although our model suggests that all Ni yields should be scaled up slightly. The outcome of this exercise is the computation of a set of integrated yields, i.e., stellar yields weighted by a slightly flattened time-independent Salpeter initial mass function and integrated over stellar mass, for each of the above elements at several metallicity points spanned by the broad range of observations. These results are designed to be used as empirical constraints on future iron-peak yield predictions by stellar evolution modelers. Special attention is paid to the interesting behavior of [Cr/Co] with metallicity-these two elements have opposite slopes-as well as the indirect correlation of [Ti/Fe] with [Fe/H]. These particular trends, as well as those exhibited by the inferred integrated yields of all iron-peak elements with metallicity, are discussed in terms of both supernova nucleosynthesis and atomic physics.

  4. Elements for successful sensor-based process control {Integrated Metrology}

    International Nuclear Information System (INIS)

    Butler, Stephanie Watts

    1998-01-01

    Current productivity needs have stimulated development of alternative metrology, control, and equipment maintenance methods. Specifically, sensor applications provide the opportunity to increase productivity, tighten control, reduce scrap, and improve maintenance schedules and procedures. Past experience indicates a complete integrated solution must be provided for sensor-based control to be used successfully in production. In this paper, Integrated Metrology is proposed as the term for an integrated solution that will result in a successful application of sensors for process control. This paper defines and explores the perceived four elements of successful sensor applications: business needs, integration, components, and form. Based upon analysis of existing successful commercially available controllers, the necessary business factors have been determined to be strong, measurable industry-wide business needs whose solution is profitable and feasible. This paper examines why the key aspect of integration is the decision making process. A detailed discussion is provided of the components of most importance to sensor based control: decision-making methods, the 3R's of sensors, and connectivity. A metric for one of the R's (resolution) is proposed to allow focus on this important aspect of measurement. A form for these integrated components which synergistically partitions various aspects of control at the equipment and MES levels to efficiently achieve desired benefits is recommended

  5. Elements for successful sensor-based process control {Integrated Metrology}

    Science.gov (United States)

    Butler, Stephanie Watts

    1998-11-01

    Current productivity needs have stimulated development of alternative metrology, control, and equipment maintenance methods. Specifically, sensor applications provide the opportunity to increase productivity, tighten control, reduce scrap, and improve maintenance schedules and procedures. Past experience indicates a complete integrated solution must be provided for sensor-based control to be used successfully in production. In this paper, Integrated Metrology is proposed as the term for an integrated solution that will result in a successful application of sensors for process control. This paper defines and explores the perceived four elements of successful sensor applications: business needs, integration, components, and form. Based upon analysis of existing successful commercially available controllers, the necessary business factors have been determined to be strong, measurable industry-wide business needs whose solution is profitable and feasible. This paper examines why the key aspect of integration is the decision making process. A detailed discussion is provided of the components of most importance to sensor based control: decision-making methods, the 3R's of sensors, and connectivity. A metric for one of the R's (resolution) is proposed to allow focus on this important aspect of measurement. A form for these integrated components which synergistically partitions various aspects of control at the equipment and MES levels to efficiently achieve desired benefits is recommended.

  6. Effects of planar element formulation and numerical integration order on checkerboard material layouts

    CSIR Research Space (South Africa)

    Long, CS

    2009-01-01

    Full Text Available The effects of selected planar finite element formulations, and their associated integration schemes, on the stiffness of a checkerboard material layout are investigated. Standard 4-node bilinear elements, 8- and 9-node quadratic elements, as well...

  7. DPTEdb, an integrative database of transposable elements in dioecious plants.

    Science.gov (United States)

    Li, Shu-Fen; Zhang, Guo-Jun; Zhang, Xue-Jin; Yuan, Jin-Hong; Deng, Chuan-Liang; Gu, Lian-Feng; Gao, Wu-Jun

    2016-01-01

    Dioecious plants usually harbor 'young' sex chromosomes, providing an opportunity to study the early stages of sex chromosome evolution. Transposable elements (TEs) are mobile DNA elements frequently found in plants and are suggested to play important roles in plant sex chromosome evolution. The genomes of several dioecious plants have been sequenced, offering an opportunity to annotate and mine the TE data. However, comprehensive and unified annotation of TEs in these dioecious plants is still lacking. In this study, we constructed a dioecious plant transposable element database (DPTEdb). DPTEdb is a specific, comprehensive and unified relational database and web interface. We used a combination of de novo, structure-based and homology-based approaches to identify TEs from the genome assemblies of previously published data, as well as our own. The database currently integrates eight dioecious plant species and a total of 31 340 TEs along with classification information. DPTEdb provides user-friendly web interfaces to browse, search and download the TE sequences in the database. Users can also use tools, including BLAST, GetORF, HMMER, Cut sequence and JBrowse, to analyze TE data. Given the role of TEs in plant sex chromosome evolution, the database will contribute to the investigation of TEs in structural, functional and evolutionary dynamics of the genome of dioecious plants. In addition, the database will supplement the research of sex diversification and sex chromosome evolution of dioecious plants.Database URL: http://genedenovoweb.ticp.net:81/DPTEdb/index.php. © The Author(s) 2016. Published by Oxford University Press.

  8. Integrated System Validation Usability Questionnaire: Information Display Element

    International Nuclear Information System (INIS)

    Garcés, Ma. I.; Torralba, B.

    2015-01-01

    The Research and Development (R&D) project on “Theoretical and Methodological Approaches to Integrated System Validation of Control Rooms, 2014-2015”, in which the research activities described in this report are framed, has two main objectives: to develop the items for an usability methodology conceived as a part of the measurement framework for performance-based control room evaluation that the OECD Halden Reactor Project will test in the experiments planned for 2015; and the statistical analysis of the data generated in the experimental activities of the Halden Man-Machine Laboratory (HAMMLAB) facility, with previous usability questionnaires, in 2010 and 2011. In this report, the procedure designed to meet the first goal of the project is described, in particular, the process followed to identify the items related to information displays, one of the elements to be included in the usability questionnaire. Three phases are performed, in the first one, the approaches developed by the United States Nuclear Regulatory Commission, NRC, are reviewed and the models proposed by the nuclear energy industry and their technical support organizations, mainly, the United States Electric Power Research Institute, EPRI, are analyzed. In the remaining stages, general and specific guidelines for information displays, in particular, display pages, formats, elements and data quality and update rate recommendations are compared and criteria for the preliminary selection of the items that should be incorporated into the usability questionnaire are defined. This proposal will be reviewed and adapted by the Halden Reactor Project to the design of the specific experiments performed in HAMMLAB.

  9. A discontinous Galerkin finite element method with an efficient time integration scheme for accurate simulations

    KAUST Repository

    Liu, Meilin; Bagci, Hakan

    2011-01-01

    A discontinuous Galerkin finite element method (DG-FEM) with a highly-accurate time integration scheme is presented. The scheme achieves its high accuracy using numerically constructed predictor-corrector integration coefficients. Numerical results

  10. Mono(p-tolyl)platinum(II) and bis(p-tolyl)platinum(II) complexes of diethylsulfide as reagents for organoplatinum synthesis. Structures of [Pt(p-Tol)2(µ-SEt2)]2 and PtCl(p-Tol)(bpy) (bpy = 2,2'-bipyridine)

    NARCIS (Netherlands)

    Koten, G. van; Casado Lacabra, M.A.; Canty, A.J.; Lutz, M.H.; Patel, J.; Spek, A.L.; Sun, H.

    2001-01-01

    The complex trans-PtCl(p-Tol)(SEt{2}){2} is obtained from the reaction of [Pt(p-Tol){2}(SEt{2})]{2} with PtCl{2}(SEt{2}){2} and SEt{2} in mole ratio 1:2:2. The mono(p-tolyl)platinum(II) and bis(p-tolyl)platinum(II) complexes of diethylsulfide react with 2, 2'-bipyridine to form the complexes

  11. SXT/R391 Integrative and Conjugative Elements (ICEs) Encode a Novel 'Trap-Door' Strategy for Mobile Element Escape.

    Science.gov (United States)

    Ryan, Michael P; Armshaw, Patricia; Pembroke, J Tony

    2016-01-01

    Integrative conjugative elements (ICEs) are a class of bacterial mobile elements that have the ability to mediate their own integration, excision, and transfer from one host genome to another by a mechanism of site-specific recombination, self-circularisation, and conjugative transfer. Members of the SXT/R391 ICE family of enterobacterial mobile genetic elements display an unusual UV-inducible sensitization function which results in stress induced killing of bacterial cells harboring the ICE. This sensitization has been shown to be associated with a stress induced overexpression of a mobile element encoded conjugative transfer gene, orf43, a traV homolog. This results in cell lysis and release of a circular form of the ICE. Induction of this novel system may allow transfer of an ICE, enhancing its survival potential under conditions not conducive to conjugative transfer.

  12. A boundary integral equation for boundary element applications in multigroup neutron diffusion theory

    International Nuclear Information System (INIS)

    Ozgener, B.

    1998-01-01

    A boundary integral equation (BIE) is developed for the application of the boundary element method to the multigroup neutron diffusion equations. The developed BIE contains no explicit scattering term; the scattering effects are taken into account by redefining the unknowns. Boundary elements of the linear and constant variety are utilised for validation of the developed boundary integral formulation

  13. The Analysis on the Integration and Embodiment of Traditional Cultural Element in Environmental Artistic Design

    Science.gov (United States)

    Ling, Bao

    2018-03-01

    For this phase of environmental artistic design, the traditional culture element is one very precious design element, but it has difficulty in breaking out of its shell, and that looks too outdated, however, the traditional culture element would be more peculiar if ponderously adding some elements. This paper will further analyse the integration and manifestation of traditional culture element which from the environmental artistic design, it aims to integrate the tradition and modernity perfectly and give the spectators a refreshing and unconventional sense of design.

  14. Super-Light Prefabricated Deck Element Integrated in Traditional Concrete Prefabricated Element Construction

    DEFF Research Database (Denmark)

    Christensen, Jacob Ellehauge; Hertz, Kristian Dahl

    Super-light structures in form of deck elements have been used for the first time in a building to construct indoor pedestrian bridges. Examples of connections to external structures and other super-light deck elements are given along with other details. Other examples on the great versatility...

  15. The natural gas as integration element in Latin America

    International Nuclear Information System (INIS)

    Morales, Maria Elizabeth; Dutra, Luis Eduardo; Rosa, Luiz Pinguelli

    1999-01-01

    The article discusses the following global aspects of natural gas development: natural gas and worldwide energetic integration; natural gas consumption rates in the world; natural gas industry development in Latin America; and natural gas industry in Brazil. The article concludes that the natural gas can integrate Latin-american economies since the Governments adopt coherent energetic politicians articulated to each other

  16. Integrating Health Behavior Theory and Design Elements in Serious Games.

    Science.gov (United States)

    Cheek, Colleen; Fleming, Theresa; Lucassen, Mathijs Fg; Bridgman, Heather; Stasiak, Karolina; Shepherd, Matthew; Orpin, Peter

    2015-01-01

    Internet interventions for improving health and well-being have the potential to reach many people and fill gaps in service provision. Serious gaming interfaces provide opportunities to optimize user adherence and impact. Health interventions based in theory and evidence and tailored to psychological constructs have been found to be more effective to promote behavior change. Defining the design elements which engage users and help them to meet their goals can contribute to better informed serious games. To elucidate design elements important in SPARX, a serious game for adolescents with depression, from a user-centered perspective. We proposed a model based on an established theory of health behavior change and practical features of serious game design to organize ideas and rationale. We analyzed data from 5 studies comprising a total of 22 focus groups and 66 semistructured interviews conducted with youth and families in New Zealand and Australia who had viewed or used SPARX. User perceptions of the game were applied to this framework. A coherent framework was established using the three constructs of self-determination theory (SDT), autonomy, competence, and relatedness, to organize user perceptions and design elements within four areas important in design: computer game, accessibility, working alliance, and learning in immersion. User perceptions mapped well to the framework, which may assist developers in understanding the context of user needs. By mapping these elements against the constructs of SDT, we were able to propose a sound theoretical base for the model. This study's method allowed for the articulation of design elements in a serious game from a user-centered perspective within a coherent overarching framework. The framework can be used to deliberately incorporate serious game design elements that support a user's sense of autonomy, competence, and relatedness, key constructs which have been found to mediate motivation at all stages of the change

  17. Thermal performance of capillary micro tubes integrated into the sandwich element made of concrete

    DEFF Research Database (Denmark)

    Mikeska, Tomas; Svendsen, Svend

    2013-01-01

    integrated into the thin plate of sandwich element made of HPC can supply the energy needed for heating and cooling. The investigations were conceived as a low temperature concept, where the difference between the temperature of circulating fluid and air in the room was kept in range of 1 to 4°C. © (2013......The thermal performance of radiant heating and cooling systems (RHCS) composed of capillary micro tubes (CMT) integrated into the inner plate of sandwich elements made of High Performance Concrete (HPC) was investigated in the article. Temperature distribution in HPC elements around integrated CMT...

  18. Hybrid Finite Element and Volume Integral Methods for Scattering Using Parametric Geometry

    DEFF Research Database (Denmark)

    Volakis, John L.; Sertel, Kubilay; Jørgensen, Erik

    2004-01-01

    n this paper we address several topics relating to the development and implementation of volume integral and hybrid finite element methods for electromagnetic modeling. Comparisons of volume integral equation formulations with the finite element-boundary integral method are given in terms of accu...... of vanishing divergence within the element but non-zero curl. In addition, a new domain decomposition is introduced for solving array problems involving several million degrees of freedom. Three orders of magnitude CPU reduction is demonstrated for such applications....

  19. Some considerations on displacement assumed finite elements with the reduced numerical integration technique

    International Nuclear Information System (INIS)

    Takeda, H.; Isha, H.

    1981-01-01

    The paper is concerned with the displacement-assumed-finite elements by applying the reduced numerical integration technique in structural problems. The first part is a general consideration on the technique. Its purpose is to examine a variational interpretation of the finite element displacement formulation with the reduced integration technique in structural problems. The formulation is critically studied from a standpoint of the natural stiffness approach. It is shown that these types of elements are equivalent to a certain type of displacement and stress assumed mixed elements. The rank deficiency of the stiffness matrix of these elements is interpreted as a problem in the transformation from the natural system to a Cartesian system. It will be shown that a variational basis of the equivalent mixed formulation is closely related to the Hellinger-Reissner's functional. It is presented that for simple elements, e.g. bilinear quadrilateral plane stress and plate bending there are corresponding mixed elements from the functional. For relatively complex types of these elements, it is shown that they are equivalent to localized mixed elements from the Hellinger-Reissner's functional. In the second part, typical finite elements with the reduced integration technique are studied to demonstrate this equivalence. A bilinear displacement and rotation assumed shear beam element, a bilinear displacement assumed quadrilateral plane stress element and a bilinear deflection and rotation assumed quadrilateral plate bending element are examined to present equivalent mixed elements. Not only the theoretical consideration is presented but numerical studies are shown to demonstrate the effectiveness of these elements in practical analysis. (orig.)

  20. Integral excitation functions for proton and alpha induced reactions on target elements 22 <= Z <= 28

    International Nuclear Information System (INIS)

    Brinkmann, G.

    1979-01-01

    In the framework of a systematic study which is also important for certain cosmological questions a series of integral excitation functions of p- and α-induced nuclear reactions on target elements 22 [de

  1. Preliminary study or RSG-GAS reactor fuel element integrity

    International Nuclear Information System (INIS)

    Soejoedi, A.; Tarigan, A.; Sujalmo; Prayoga, S.; Suhadi

    1996-01-01

    After 8 years of operation, RSG-GAS was able to reach 15 cycles of reactor operation with 116 irradiated fuels, whereas 49 fuels were produced by NUKEM; and the other 67 were produced by PEBN-BATAN. At the 15 T h cycles, it have been used 40 standard fuels and 8 control fuels (Forty standard fuels and eight control fuels have been used in the 15 t h core cycles). Several activities have been performed in the reactor, to investigate the fuel integrity, among of them are: .fuel visual test with under water camera, which the results were recorder in the video cassette, primary water quality test during, reactor operation, fuel failure detector system examination and compared the PIE results in the Radiometallurgy Installation (RMI). The results showed that the fuel integrity, before and after irradiation, have still good performance and the fission products have not been released yet

  2. Safeguards-by-Design: An Element of 3S Integration

    International Nuclear Information System (INIS)

    Bean, R.S.; Bjornard, T.A.; Hebdich, D.J.

    2009-01-01

    In 2008, the '20/20 Vision for the Future' background report by the IAEA Director General identified the possibility of integrating certain activities related to safeguards, safety, and security. Later in the year, the independent Commission report prepared at the request of the IAEA Director General noted that the Agency's's roles in nuclear safeguards, safety, and security (3S) complement and can mutually reinforce each other. Safeguards-by-design (SBD) is a practical measure that strengthens 3S integration, especially for the stage of nuclear facility design and construction, but also with ramifications for other stages of the facility life-cycle. This paper describes the SBD concept, with examples for diverse regulatory environments, being developed in the U.S under the U.S. Department of Energy (DOE) Next Generation Safeguards Initiative and the Advanced Fuel Cycle Initiative. This is compared with related international SBD work performed in the recent IAEA workshop on 'Facility Design and Plant Operation Features that Facilitate the Implementation of IAEA Safeguards'. Potential future directions for further development of SBD and its integration within 3S are identified.

  3. A Novel Virtual Node Hexahedral Element with Exact Integration and Octree Meshing

    Directory of Open Access Journals (Sweden)

    Logah Perumal

    2016-01-01

    Full Text Available The method presented in this work is a 3-dimensional polyhedral finite element (3D PFEM based on virtual node method. Novel virtual node polyhedral elements (termed as VPHE are developed here, particularly virtual node hexahedral element (termed as VHE. Stiffness matrices of these polyhedral elements consist of simple polynomials. Thus, a new algorithm is introduced in this paper, which enables exact integration of monomials without a need for high number of integration points and weights. The number of nodes for VHE elements is not restricted, as opposed to the conventional hexahedral elements. This feature enables formulation of transition elements (termed as T-VHE which are useful to adaptive computation. Performances of the new VHE elements in solid mechanics and conductive heat transfer phenomena are examined through numerical simulations. The new T-VHE elements are utilized in octree mesh. The VHE elements are found to produce good results and T-VHE elements help to reduce number of global nodes for the analysis.

  4. 49 CFR 192.911 - What are the elements of an integrity management program?

    Science.gov (United States)

    2010-10-01

    ...) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY TRANSPORTATION OF NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Gas Transmission Pipeline Integrity Management § 192.911 What are the elements of an integrity management program...

  5. Engineering planetary exploration systems : Integrating novel technologies and the human element using work domain analysis

    NARCIS (Netherlands)

    Baker, C.; Naikar, N.; Neerincx, M.

    2008-01-01

    The realisation of sustainable space exploration and utilisation requires not only the development of novel concepts and technologies, but also their successful integration. Hardware, software, and the human element must be integrated effectively to make the dream for which these technologies were

  6. Government Advertising: an integrative element. The legal framework in Spain

    Directory of Open Access Journals (Sweden)

    Dr. Ricardo Vizcaíno-Laorga

    2008-01-01

    Full Text Available Immigration in Spain has had a special increase last ten years. America is a main origin. The advertising from companies is similar like few years ago, but the context has changed. Advertising from Government is being managed to this new sensibility, but slow and not from a logical strategy. A Law about Government Advertising and Communication has been promulgated and it assure the social and cultural diversity. Integration and acceptance are the objectives of the campaigns from the Government. This research show the data of a pioneer study in which the immigrants are the analyst (not the analyzed and show their feeling. This text describe the campaigns from the Government in which the immigrant appear

  7. The driving elements of an integrated configuration management program

    International Nuclear Information System (INIS)

    Zaalouk, M.G.

    1990-01-01

    The need for an effective long term Plant Configuration Management Program (CMP) has been demonstrated in response to Plant Design Modification and Plant Life Extension activities. Having particular need are those Utilities operating early vintage nuclear plants, where numerous modifications have been made without the benefit of an accurate, complete, properly maintained and controlled Design Basis. This paper presents a model for a long term, cost effective CMP which is based on and driven by the development, maintenance and control of accurate plant Design Basis Information. The model also provides a systematic approach for devising and implementing an integrated Plant CMP based on the essential attributes of the Plant Configuration Management, including Design Basis

  8. Automated element identification for EDS spectra evaluation using quantification and integrated spectra simulation approaches

    International Nuclear Information System (INIS)

    Eggert, F

    2010-01-01

    This work describes first real automated solution for qualitative evaluation of EDS spectra in X-ray microanalysis. It uses a combination of integrated standardless quantitative evaluation, computation of analytical errors to a final uncertainty, and parts of recently developed simulation approaches. Multiple spectra reconstruction assessments and peak searches of the residual spectrum are powerful enough to solve the qualitative analytical question automatically for totally unknown specimens. The integrated quantitative assessment is useful to improve the confidence of the qualitative analysis. Therefore, the qualitative element analysis becomes a part of integrated quantitative spectrum evaluation, where the quantitative results are used to iteratively refine element decisions, spectrum deconvolution, and simulation steps.

  9. A discontinous Galerkin finite element method with an efficient time integration scheme for accurate simulations

    KAUST Repository

    Liu, Meilin

    2011-07-01

    A discontinuous Galerkin finite element method (DG-FEM) with a highly-accurate time integration scheme is presented. The scheme achieves its high accuracy using numerically constructed predictor-corrector integration coefficients. Numerical results show that this new time integration scheme uses considerably larger time steps than the fourth-order Runge-Kutta method when combined with a DG-FEM using higher-order spatial discretization/basis functions for high accuracy. © 2011 IEEE.

  10. Integrated Process Design and Control of Multi-element Reactive Distillation Processes

    DEFF Research Database (Denmark)

    Mansouri, Seyed Soheil; Sales-Cruz, Mauricio; Huusom, Jakob Kjøbsted

    2016-01-01

    In this work, integrated process design and control of reactive distillation processes involving multi-elements is presented. The reactive distillation column is designed using methods and tools which are similar in concept to non-reactive distillation design methods, such as driving force approach....... The methods employed in this work are based on equivalent element concept. This concept facilitates the representation of a multi-element reactive system as equivalent binary light and heavy key elements. First, the reactive distillation column is designed at the maximum driving force where through steady...

  11. Development of efficient finite elements for structural integrity analysis of solid rocket motor propellant grains

    International Nuclear Information System (INIS)

    Marimuthu, R.; Nageswara Rao, B.

    2013-01-01

    Solid propellant rocket motors (SRM) are regularly used in the satellite launch vehicles which consist of mainly three different structural materials viz., solid propellant, liner, and casing materials. It is essential to assess the structural integrity of solid propellant grains under the specified gravity, thermal and pressure loading conditions. For this purpose finite elements developed following the Herrmann formulation are: twenty node brick element (BH20), eight node quadrilateral plane strain element (PH8) and, eight node axi-symmetric solid of revolution element (AH8). The time-dependent nature of the solid propellant grains is taken into account utilizing the direct inverse method of Schepary to specify the effective Young's modulus and Poisson's ratio. The developed elements are tested considering various problems prior to implementation in the in-house software package (viz., Finite Element Analysis of STructures, FEAST). Several SRM configurations are analyzed to assess the structural integrity under different loading conditions. Finite element analysis results are found to be in good agreement with those obtained earlier from MARC software. -- Highlights: • Developed efficient Herrmann elements. • Accuracy of finite elements demonstrated solving several known solution problems. • Time dependent structural response obtained using the direct inverse method of Schepary. • Performed structural analysis of grains under gravity, thermal and pressure loads

  12. Study on boiling heat transfer from diode elements in an integrated circuit chip

    Energy Technology Data Exchange (ETDEWEB)

    Hijikata, Kunio; Nagasaki, Takao; Kurata, Naoki (Tokyo Institute of Technology Faculty of Engineering (Japan))

    1989-02-25

    By temperature measurement of elements in boiling experiments with diodes in an integrated circuit (IC) chip, characteristics of boiling heat transfer from tiny heat generating elements in an IC chip and thermal transfer characteristics of multiple heating elements adjoining positioned were studied. The Package of an IC was removed by acid to expose the IC chip. Electricity is applied to the diode in the IC to study the heat transfer properties. The heat transfer rate from a tiny heating element on an IC is greater than that from the conventional continual heated surface. In the case of heat generation by two adjoining elements, the relationship between the total amount of heat and the temperature of elements shows the same characteristics as in the case with a single element. The boiling heat transfer properties of an element in an IC chip are influenced by such microstructure surrounding the element as the pattern of wiring. Heat transfer increases with the decreasing size of the heating element by the heat transfer to the substrate beneath the element. 10 refs., 15 figs.

  13. Steps in creating a methodology for interpreting a geodiversity element -integrating a geodiversity element in the popular knowledge

    Science.gov (United States)

    Toma, Cristina; Andrasanu, Alexandru

    2017-04-01

    Conserving geodiversity and especially geological heritage is not very well integrated in the general knowledge as biodiversity is, for example. Keeping that in mind we are trying, through this research, to find a better way of transmitting a geological process to the general public. The means to integrate a geodiversity element in the popular knowledge is through interpretation. Interpretation "translates" the scientific information into a common language with very well known facts by the general public. The purpose of this paper is creating a framework for a methodology necessary in interpreting a geodiversity element - salt - in Buzau Land Geopark. We will approach the salt subject through a scheme in order to have a general view of the process and to better understand and explain it to the general public. We will look into the subject from three scientific points of view: GEODIVERSITY, ANTHROPOLOGY, and the SOCIO-ECONOMICAL aspect. Each of these points of view or domains will be divided into themes. For GEODIVERSITY we will have the following themes: Formation, Accumulation, Diapirism process, Chemical formula, Landscape (here we will include also the specific biodiversity with the halophile plants), Landforms, Hazard. For ANTHROPOLOGY will contain themes of tangible and intangible heritage like: Salt symbolistic, Stories and ritual usage, Recipes, How the knowledge is transmitted. The SOCIO-ECONOMIC aspect will be reflected through themes like: Extractive methods, Usage, Interdictions, Taxes, Commercial exchanges. Each theme will have a set of keywords that will be described and each one will be at the base of the elements that together will form the interpretation of the geodiversity element - the salt. The next step will be to clearly set the scope of the interpretation, to which field of expertise is our interpretation process addressed: Education (Undergraduate or post-graduate Students), Science, Geotourism, Entrepreneurship. After putting together the

  14. Strategic Alliance Development - A Process Model A Case Study Integrating Elements of Strategic Alliances

    OpenAIRE

    Mohd Yunos, Mohd Bulkiah

    2007-01-01

    There has been enormous increase in the formation of strategic alliance and the research efforts devoted to understanding alliance development process over the last few decades. However, the critical elements that influence the each stage of alliance development are yet unexplored. This dissertation aims to fill this gap and to supplement it by introducing an integrated process model of strategic alliance development and its critical elements. The process model for strategic alliance developm...

  15. Selective pressures to maintain attachment site specificity of integrative and conjugative elements.

    Directory of Open Access Journals (Sweden)

    Kayla L Menard

    Full Text Available Integrative and conjugative elements (ICEs are widespread mobile genetic elements that are usually found integrated in bacterial chromosomes. They are important agents of evolution and contribute to the acquisition of new traits, including antibiotic resistances. ICEs can excise from the chromosome and transfer to recipients by conjugation. Many ICEs are site-specific in that they integrate preferentially into a primary attachment site in the bacterial genome. Site-specific ICEs can also integrate into secondary locations, particularly if the primary site is absent. However, little is known about the consequences of integration of ICEs into alternative attachment sites or what drives the apparent maintenance and prevalence of the many ICEs that use a single attachment site. Using ICEBs1, a site-specific ICE from Bacillus subtilis that integrates into a tRNA gene, we found that integration into secondary sites was detrimental to both ICEBs1 and the host cell. Excision of ICEBs1 from secondary sites was impaired either partially or completely, limiting the spread of ICEBs1. Furthermore, induction of ICEBs1 gene expression caused a substantial drop in proliferation and cell viability within three hours. This drop was dependent on rolling circle replication of ICEBs1 that was unable to excise from the chromosome. Together, these detrimental effects provide selective pressure against the survival and dissemination of ICEs that have integrated into alternative sites and may explain the maintenance of site-specific integration for many ICEs.

  16. Integrator element as a promoter of active learning in engineering teaching

    Science.gov (United States)

    Oliveira, Paulo C.; Oliveira, Cristina G.

    2014-03-01

    In this paper, we present a teaching proposal used in an Introductory Physics course to civil engineering students from Porto's Engineering Institute/Instituto Superior de Engenharia do Porto (ISEP). The proposal was born from the need to change students' perception and motivation for learning physics. It consists in the use of an integrator element, called the physics elevator project. This integrator element allows us to use, in a single project, all the content taught in the course and uses several active learning strategies. In this paper, we analyse this project as: (i) a clarifying element of the contents covered in the course; (ii) a promoter element of motivation and active participation in class and finally and (iii) a link between the contents covered in the course and the 'real world'. The data were collected by a questionnaire and interviews to students. From the data collected, it seems that the integrator element improves students' motivation towards physics and develops several skills that they consider to be important to their professional future. It also acts as a clarifying element and makes the connection between the physics that is taught and the 'real world'.

  17. Systematic Integrated Process Design and Control of Binary Element Reactive Distillation Processes

    DEFF Research Database (Denmark)

    Mansouri, Seyed Soheil; Sales-Cruz, Mauricio; Huusom, Jakob Kjøbsted

    2016-01-01

    In this work, integrated process design and control of reactive distillation processes is considered through a computer-aided framework. First, a set of simple design methods for reactive distillation column that are similar in concept to non-reactive distillation design methods are extended...... to design-control of reactive distillation columns. These methods are based on the element concept where the reacting system of compounds is represented as elements. When only two elements are needed to represent the reacting system of more than two compounds, a binary element system is identified....... It is shown that the same design-control principles that apply to a non-reacting binary system of compounds are also valid for a reactive binary system of elements for distillation columns. Application of this framework shows that designing the reactive distillation process at the maximum driving force...

  18. Recent progress of an integrated implosion code and modeling of element physics

    International Nuclear Information System (INIS)

    Nagatomo, H.; Takabe, H.; Mima, K.; Ohnishi, N.; Sunahara, A.; Takeda, T.; Nishihara, K.; Nishiguchu, A.; Sawada, K.

    2001-01-01

    Physics of the inertial fusion is based on a variety of elements such as compressible hydrodynamics, radiation transport, non-ideal equation of state, non-LTE atomic process, and relativistic laser plasma interaction. In addition, implosion process is not in stationary state and fluid dynamics, energy transport and instabilities should be solved simultaneously. In order to study such complex physics, an integrated implosion code including all physics important in the implosion process should be developed. The details of physics elements should be studied and the resultant numerical modeling should be installed in the integrated code so that the implosion can be simulated with available computer within realistic CPU time. Therefore, this task can be basically separated into two parts. One is to integrate all physics elements into a code, which is strongly related to the development of hydrodynamic equation solver. We have developed 2-D integrated implosion code which solves mass, momentum, electron energy, ion energy, equation of states, laser ray-trace, laser absorption radiation, surface tracing and so on. The reasonable results in simulating Rayleigh-Taylor instability and cylindrical implosion are obtained using this code. The other is code development on each element physics and verification of these codes. We had progress in developing a nonlocal electron transport code and 2 and 3 dimension radiation hydrodynamic code. (author)

  19. An integrated finite-element approach to mechanics, transport and biosynthesis in tissue engineering

    NARCIS (Netherlands)

    Sengers, B.G.; Oomens, C.W.J.; Baaijens, F.P.T.

    2004-01-01

    A finite-element approach was formulated, aimed at enabling an integrated study of mechanical and biochemical factors that control the functional development of tissue engineered constructs. A nonlinear biphasic displacement-velocity-pressure description was combined with adjective and diffusive

  20. Evaluation of the Cultural Elements in the Textbook "Genki I: an Integrated Course in Elementary Japanese"

    Science.gov (United States)

    Er, Onur

    2017-01-01

    This study aims to examine the textbook "Genki I: An Integrated Course in Elementary Japanese" in terms of cultural elements. The data of this qualitative research were collected by means of the document review method. Content analysis, one of the qualitative analysis techniques, was used in the evaluation of the research data. A second…

  1. Time-integration methods for finite element discretisations of the second-order Maxwell equation

    NARCIS (Netherlands)

    Sarmany, D.; Bochev, Mikhail A.; van der Vegt, Jacobus J.W.

    This article deals with time integration for the second-order Maxwell equations with possibly non-zero conductivity in the context of the discontinuous Galerkin finite element method DG-FEM) and the $H(\\mathrm{curl})$-conforming FEM. For the spatial discretisation, hierarchic

  2. An improved acoustic Fourier boundary element method formulation using fast Fourier transform integration

    NARCIS (Netherlands)

    Kuijpers, A.H.W.M.; Verbeek, G.; Verheij, J.W.

    1997-01-01

    Effective use of the Fourier series boundary element method (FBEM) for everyday applications is hindered by the significant numerical problems that have to be overcome for its implementation. In the FBEM formulation for acoustics, some integrals over the angle of revolution arise, which need to be

  3. Use of the integration elements encoded by the temperate lactococcal bacteriophage TP901-1

    DEFF Research Database (Denmark)

    Brøndsted, Lone; Hammer, Karin

    1999-01-01

    Previously we showed that only one phage-expressed protein (Orf1), a 425-bp region upstream of the orf1 gene (presumably encoding a promoter), and the attP region are necessary and also sufficient for integration of the bacteriophage TP901-1 genome into the chromosome of Lactococcus lactis subsp......P region seem to be necessary for site-specific integration of the temperate bacteriophage TP901-1. By use of the integrative elements (attP and orf1) expressed by the temperate lactococcal bacteriophage TP901-1, a system for obtaining stable chromosomal single-copy transcriptional fusions in L. lactis...

  4. Demosite - Demonstration of the integration of photovoltaic elements in buildings; DEMOSITE. Site de demonstration d'elements de construction photovoltaiques integres au batiment

    Energy Technology Data Exchange (ETDEWEB)

    Roecker, C.; Affolter, P.; Muller, A.N.; Ould-Yenia, A.

    2003-07-01

    This final report for the Swiss Federal Office of Energy summarises Phase 4 of the DEMOSITE project and concludes 10 years of DEMOSITE activities. The DEMOSITE project, started in 1992, demonstrates various ways of integrating photovoltaic elements in buildings by providing stands, pavilions and monitoring facilities at its site in Lausanne, Switzerland. Here, at the Swiss Federal Institute of Technology, roof-mounted installations can be found as well as mock-ups of buildings and roofing systems that also serve as covered parking facilities. The DEMOSITE web site and graphical presentations are also reviewed. Furthermore, the six newest pavilions are presented in detail. The report also presents several sets of data from measurements made on the installations and discusses the dissemination of information and results obtained from the project. A comprehensive annex provides illustrations of examples of building-integrated photovoltaics from around the world.

  5. Reduced and selective integration techniques in the finite element analysis of plates

    International Nuclear Information System (INIS)

    Hughes, T.J.R.; Cohen, M.; Haroun, M.

    1978-01-01

    Efforts to develop effective plate bending finite elements by reduced integration techniques are described. The basis for the development is a 'thick' plate theory in which transverse shear strains are accounted for. The variables in the theory are all kinematic, namely, displacements and independent rotations. As only C 0 continuity is required, isoparametric elements may be employed, which result in several advantages over thin plate elements. It is shown that the avoidance of shear 'locking' may be facilitated by reduced integration techniques. Both uniform and selective schemes are considered. Conditions under which selective schemes are invariant are identified, and they are found to have an advantage over uniform schemes in the present situation. It is pointed out that the present elements are not subject to the difficulties encountered by thin plate theory elements, concerning boundary conditions. For example, the polygonal approximation of curved, simply supported edges is convergent. Other topics discussed are the equivalence with mixed methods, rank deficiency, convergence criteria and useful mass 'lumping' schemes for dynamics. Numerical results for several thin plate problems indicate the high degree of accuracy attainable by the present elements. (Auth.)

  6. Analysis of Elastic-Plastic J Integrals for 3-Dimensional Cracks Using Finite Element Alternating Method

    International Nuclear Information System (INIS)

    Park, Jai Hak

    2009-01-01

    SGBEM(Symmetric Galerkin Boundary Element Method)-FEM alternating method has been proposed by Nikishkov, Park and Atluri. In the proposed method, arbitrarily shaped three-dimensional crack problems can be solved by alternating between the crack solution in an infinite body and the finite element solution without a crack. In the previous study, the SGBEM-FEM alternating method was extended further in order to solve elastic-plastic crack problems and to obtain elastic-plastic stress fields. For the elastic-plastic analysis the algorithm developed by Nikishkov et al. is used after modification. In the algorithm, the initial stress method is used to obtain elastic-plastic stress and strain fields. In this paper, elastic-plastic J integrals for three-dimensional cracks are obtained using the method. For that purpose, accurate values of displacement gradients and stresses are necessary on an integration path. In order to improve the accuracy of stress near crack surfaces, coordinate transformation and partitioning of integration domain are used. The coordinate transformation produces a transformation Jacobian, which cancels the singularity of the integrand. Using the developed program, simple three-dimensional crack problems are solved and elastic and elastic-plastic J integrals are obtained. The obtained J integrals are compared with the values obtained using a handbook solution. It is noted that J integrals obtained from the alternating method are close to the values from the handbook

  7. A solution for the integration of finite element analysis in a ship design environment

    International Nuclear Information System (INIS)

    Finifter, D.; Wyniecki, P.; Castel, J. de

    1982-01-01

    The DEMAIN system for the pre- and post-processing of finite element analyses of ship structures is presented. It is shown that this new modelling concept, although being self-contained and specialized, has features which relate it to computer-aided design applications of a more general nature. Thus, compared to other finite element pre/post-processors, it allows a more natural occurrence of the structural analysis task in the design flow and can be considered a major step towards an integrated design and analysis system. (orig.)

  8. Elements of integrated care approaches for older people: a review of reviews.

    Science.gov (United States)

    Briggs, Andrew M; Valentijn, Pim P; Thiyagarajan, Jotheeswaran A; Araujo de Carvalho, Islene

    2018-04-07

    The World Health Organization (WHO) recently proposed an Integrated Care for Older People approach to guide health systems and services in better supporting functional ability of older people. A knowledge gap remains in the key elements of integrated care approaches used in health and social care delivery systems for older populations. The objective of this review was to identify and describe the key elements of integrated care models for elderly people reported in the literature. Review of reviews using a systematic search method. A systematic search was performed in MEDLINE and the Cochrane database in June 2017. Reviews of interventions aimed at care integration at the clinical (micro), organisational/service (meso) or health system (macro) levels for people aged ≥60 years were included. Non-Cochrane reviews published before 2015 were excluded. Reviews were assessed for quality using the Assessment of Multiple Systematic Reviews (AMSTAR) 1 tool. Fifteen reviews (11 systematic reviews, of which six were Cochrane reviews) were included, representing 219 primary studies. Three reviews (20%) included only randomised controlled trials (RCT), while 10 reviews (65%) included both RCTs and non-RCTs. The region where the largest number of primary studies originated was North America (n=89, 47.6%), followed by Europe (n=60, 32.1%) and Oceania (n=31, 16.6%). Eleven (73%) reviews focused on clinical 'micro' and organisational 'meso' care integration strategies. The most commonly reported elements of integrated care models were multidisciplinary teams, comprehensive assessment and case management. Nurses, physiotherapists, general practitioners and social workers were the most commonly reported service providers. Methodological quality was variable (AMSTAR scores: 1-11). Seven (47%) reviews were scored as high quality (AMSTAR score ≥8). Evidence of elements of integrated care for older people focuses particularly on micro clinical care integration processes, while there

  9. A comparison of integral block and tubular interacting fuel element concepts for low enrichment HTR

    Energy Technology Data Exchange (ETDEWEB)

    Desoisa, J A

    1972-04-15

    The tubular interacting fuel element has to date been the favoured U.K. high temperature reactor design. Recent attempts to lower fuel costs and the progress of the Fort St. Vrain reactor has focussed attention on alternative designs, and in particular on the attractive design simplicity of the integral block concept. The aim of this investigation is to compare the merits of both concepts from fuel cycle cost and thermal performance viewpoints and to determine whether optimization of the integral block concept leads to changes in the current design values of (a) fuel density, (b) Nc/Nu, and/or (c) mean discharge irradiation within the framework of present design limits.

  10. Integration of Solid-phase Extraction with Electrothermal Atomic Absorption Spectrometry for Determination of Trace Elements

    OpenAIRE

    NUKATSUKA, Isoshi; OHZEKI, Kunio

    2006-01-01

    An enrichment step in a sample treatment is essential for trace analysis to improve the sensitivity and to eliminate the matrix of the sample. Solid-phase extraction (SPE) is one of the widely used enrichment technique. Electrothermal atomic absorption spectrometry (ETAAS) is a well-established determination technique for trace elements. The integration of SPE with ETAAS leads to further improvement of sensitivity, an automation of the measurement and the economy in the sample size, amounts o...

  11. Integrated Circuit Interconnect Lines on Lossy Silicon Substrate with Finite Element Method

    OpenAIRE

    Sarhan M. Musa,; Matthew N. O. Sadiku

    2014-01-01

    The silicon substrate has a significant effect on the inductance parameter of a lossy interconnect line on integrated circuit. It is essential to take this into account in determining the transmission line electrical parameters. In this paper, a new quasi-TEM capacitance and inductance analysis of multiconductor multilayer interconnects is successfully demonstrated using finite element method (FEM). We specifically illustrate the electrostatic modeling of single and coupled in...

  12. RegRNA: an integrated web server for identifying regulatory RNA motifs and elements

    OpenAIRE

    Huang, Hsi-Yuan; Chien, Chia-Hung; Jen, Kuan-Hua; Huang, Hsien-Da

    2006-01-01

    Numerous regulatory structural motifs have been identified as playing essential roles in transcriptional and post-transcriptional regulation of gene expression. RegRNA is an integrated web server for identifying the homologs of regulatory RNA motifs and elements against an input mRNA sequence. Both sequence homologs and structural homologs of regulatory RNA motifs can be recognized. The regulatory RNA motifs supported in RegRNA are categorized into several classes: (i) motifs in mRNA 5′-untra...

  13. Numerical Integration Techniques for Curved-Element Discretizations of Molecule–Solvent Interfaces

    Science.gov (United States)

    Bardhan, Jaydeep P.; Altman, Michael D.; Willis, David J.; Lippow, Shaun M.; Tidor, Bruce; White, Jacob K.

    2012-01-01

    Surface formulations of biophysical modeling problems offer attractive theoretical and computational properties. Numerical simulations based on these formulations usually begin with discretization of the surface under consideration; often, the surface is curved, possessing complicated structure and possibly singularities. Numerical simulations commonly are based on approximate, rather than exact, discretizations of these surfaces. To assess the strength of the dependence of simulation accuracy on the fidelity of surface representation, we have developed methods to model several important surface formulations using exact surface discretizations. Following and refining Zauhar’s work (J. Comp.-Aid. Mol. Des. 9:149-159, 1995), we define two classes of curved elements that can exactly discretize the van der Waals, solvent-accessible, and solvent-excluded (molecular) surfaces. We then present numerical integration techniques that can accurately evaluate nonsingular and singular integrals over these curved surfaces. After validating the exactness of the surface discretizations and demonstrating the correctness of the presented integration methods, we present a set of calculations that compare the accuracy of approximate, planar-triangle-based discretizations and exact, curved-element-based simulations of surface-generalized-Born (sGB), surface-continuum van der Waals (scvdW), and boundary-element method (BEM) electrostatics problems. Results demonstrate that continuum electrostatic calculations with BEM using curved elements, piecewise-constant basis functions, and centroid collocation are nearly ten times more accurate than planartriangle BEM for basis sets of comparable size. The sGB and scvdW calculations give exceptional accuracy even for the coarsest obtainable discretized surfaces. The extra accuracy is attributed to the exact representation of the solute–solvent interface; in contrast, commonly used planar-triangle discretizations can only offer improved

  14. Assessment of dietary intake of trace elements through Pakistani integrated diets

    International Nuclear Information System (INIS)

    Qureshi, I.H.; Mannan, A.; Waheed, S.; Rehman, S.; Ahmad, S.

    1994-01-01

    A research study related to the determination and assessment of essential and potentially toxic trace elements in Pakistani integrated diets was undertaken at PINSTECH from 1986-90 under the International Atomic Energy Agency (IAEA) Co-ordinated Research Programme (CRP). During this period eight different integrated human diets of the residents of the Islamabad and Gujranwala were prepared by taking into consideration their respective food habits in summer and winter seasons. Instrumental as well as radiochemical neutron activation analyses in combination with the atomic absorption spectrometry were utilized for the precise and accurate determination of up to 23 elements in the diet samples. This work has helped us obtain the base line values for studying trace elements nutrition, inadequacy, imbalances and toxicity. Further, this would help, in future, to monitor the degree of contamination from foreign chemicals. The weekly dietary intake values were calculated which showed that our foods contain fairly adequate quantity of essential trace elements. The diet samples analyzed showed no contamination level to an extent to cause an adverse impact on human health. (author). 23 refs, 5 figs, 21 tabs

  15. Practical steps toward integrating economic, social and institutional elements in fisheries policy and management

    DEFF Research Database (Denmark)

    Stephenson, Robert L.; Benson, Ashleen J.; Brooks, Kate

    2017-01-01

    While international agreements and legislation call for incorporation of four pillars of sustainability, the social (including cultural), economic and institutional aspects (the ‘human dimension’) have been relatively neglected to date. Three key impediments have been identified: a relative lack...... of explicit social, economic and institutional objectives; a general lack of process (frameworks, governance) for routine integration of all four pillars of sustainability; and a bias towards biological considerations. Practical integration requires a ‘systems’ approach with explicit consideration...... in fisheries to immediately take five practical steps toward integrating ecological, economic, social and institutional aspects: (1) Adopt the perspective of the fishery as a ‘system’ with interacting natural, human and management elements; (2) Be aware of both strategic and operational aspects of fisheries...

  16. Integrated learning in practical machine element design course: a case study of V-pulley design

    Science.gov (United States)

    Tantrabandit, Manop

    2014-06-01

    To achieve an effective integrated learning in Machine Element Design course, it is of importance to bridge the basic knowledge and skills of element designs. The multiple core learning leads the pathway which consists of two main parts. The first part involves teaching documents of which the contents are number of V-groove formulae, standard of V-grooved pulleys, and parallel key dimension's formulae. The second part relates to the subjects that the students have studied prior to participating in this integrated learning course, namely Material Selection, Manufacturing Process, Applied Engineering Drawing, CAD (Computer Aided Design) animation software. Moreover, an intensive cooperation between a lecturer and students is another key factor to fulfill the success of integrated learning. Last but not least, the students need to share their knowledge within the group and among the other groups aiming to gain knowledge of and skills in 1) the application of CAD-software to build up manufacture part drawings, 2) assembly drawing, 3) simulation to verify the strength of loaded pulley by method of Finite Element Analysis (FEA), 4) the software to create animation of mounting and dismounting of a pulley to a shaft, and 5) an instruction manual. The end product of this integrated learning, as a result of the above 1 to 5 knowledge and skills obtained, the participating students can create an assembly derived from manufacture part drawings and a video presentation with bilingual (English-Thai) audio description of Vpulley with datum diameter of 250 mm, 4 grooves, and type of groove: SPA.

  17. Redefinition and unification of the SXT/R391 family of integrative and conjugative elements.

    Science.gov (United States)

    Bioteau, Audrey; Durand, Romain; Burrus, Vincent

    2018-04-13

    Integrative and conjugative elements (ICEs) of the SXT/R391 family are key drivers of the spread of antibiotic resistance in Vibrio cholerae , the infectious agent of cholera, and other pathogenic bacteria. The SXT/R391 family of ICEs was defined based on the conservation of a core set of 52 genes and site-specific integration into the 5' end of the chromosomal gene prfC Hence, the integrase gene int has been intensively used as a marker to detect SXT/R391 ICEs in clinical isolates. ICEs sharing most core genes but differing by their integration site and integrase gene have been recently reported and excluded from the SXT/R391 family. Here we explored the prevalence and diversity of atypical ICEs in Genbank databases and their relationship with typical SXT/R391 ICEs. We found atypical ICEs in V. cholerae isolates that predate the emergence and expansion of typical SXT/R391 ICEs in the mid-1980s in seventh pandemic toxigenic V. cholerae O1 and O139 strains. Our analyses revealed that while atypical ICEs are not associated with antibiotic resistance genes, they often carry cation efflux pumps suggesting heavy metal resistance. Atypical ICEs constitute a polyphyletic group likely because of occasional recombination events with typical ICEs. Furthermore, we show that the alternative integration and excision genes of atypical ICEs remain under the control of SetCD, the main activator of the conjugative functions of SXT/R391 ICEs. Together these observations indicate that substitution of the integration/excision module and change of specificity of integration do not preclude atypical ICEs from inclusion into the SXT/R391 family. Importance Vibrio cholerae is the causative agent of cholera, an acute intestinal infection that remains to this day a world public health threat. Integrative and conjugative elements (ICEs) of the SXT/R391 family have played a major role in spreading antimicrobial resistance in seventh pandemic V. cholerae but also in several species of

  18. Sequential induction of three recombination directionality factors directs assembly of tripartite integrative and conjugative elements.

    Directory of Open Access Journals (Sweden)

    Timothy L Haskett

    2018-03-01

    Full Text Available Tripartite integrative and conjugative elements (ICE3 are a novel form of ICE that exist as three separate DNA regions integrated within the genomes of Mesorhizobium spp. Prior to conjugative transfer the three ICE3 regions of M. ciceri WSM1271 ICEMcSym1271 combine and excise to form a single circular element. This assembly requires three coordinated recombination events involving three site-specific recombinases IntS, IntG and IntM. Here, we demonstrate that three excisionases-or recombination directionality factors-RdfS, RdfG and RdfM are required for ICE3 excision. Transcriptome sequencing revealed that expression of ICE3 transfer and conjugation genes was induced by quorum sensing. Quorum sensing activated expression of rdfS, and in turn RdfS stimulated transcription of both rdfG and rdfM. Therefore, RdfS acts as a "master controller" of ICE3 assembly and excision. The dependence of all three excisive reactions on RdfS ensures that ICE3 excision occurs via a stepwise sequence of recombination events that avoids splitting the chromosome into a non-viable configuration. These discoveries expose a surprisingly simple control system guiding molecular assembly of these novel and complex mobile genetic elements and highlight the diverse and critical functions of excisionase proteins in control of horizontal gene transfer.

  19. Sequential induction of three recombination directionality factors directs assembly of tripartite integrative and conjugative elements.

    Science.gov (United States)

    Haskett, Timothy L; Terpolilli, Jason J; Ramachandran, Vinoy K; Verdonk, Callum J; Poole, Phillip S; O'Hara, Graham W; Ramsay, Joshua P

    2018-03-01

    Tripartite integrative and conjugative elements (ICE3) are a novel form of ICE that exist as three separate DNA regions integrated within the genomes of Mesorhizobium spp. Prior to conjugative transfer the three ICE3 regions of M. ciceri WSM1271 ICEMcSym1271 combine and excise to form a single circular element. This assembly requires three coordinated recombination events involving three site-specific recombinases IntS, IntG and IntM. Here, we demonstrate that three excisionases-or recombination directionality factors-RdfS, RdfG and RdfM are required for ICE3 excision. Transcriptome sequencing revealed that expression of ICE3 transfer and conjugation genes was induced by quorum sensing. Quorum sensing activated expression of rdfS, and in turn RdfS stimulated transcription of both rdfG and rdfM. Therefore, RdfS acts as a "master controller" of ICE3 assembly and excision. The dependence of all three excisive reactions on RdfS ensures that ICE3 excision occurs via a stepwise sequence of recombination events that avoids splitting the chromosome into a non-viable configuration. These discoveries expose a surprisingly simple control system guiding molecular assembly of these novel and complex mobile genetic elements and highlight the diverse and critical functions of excisionase proteins in control of horizontal gene transfer.

  20. An adjustable RF tuning element for microwave, millimeter wave, and submillimeter wave integrated circuits

    Science.gov (United States)

    Lubecke, Victor M.; Mcgrath, William R.; Rutledge, David B.

    1991-01-01

    Planar RF circuits are used in a wide range of applications from 1 GHz to 300 GHz, including radar, communications, commercial RF test instruments, and remote sensing radiometers. These circuits, however, provide only fixed tuning elements. This lack of adjustability puts severe demands on circuit design procedures and materials parameters. We have developed a novel tuning element which can be incorporated into the design of a planar circuit in order to allow active, post-fabrication tuning by varying the electrical length of a coplanar strip transmission line. It consists of a series of thin plates which can slide in unison along the transmission line, and the size and spacing of the plates are designed to provide a large reflection of RF power over a useful frequency bandwidth. Tests of this structure at 1 GHz to 3 Ghz showed that it produced a reflection coefficient greater than 0.90 over a 20 percent bandwidth. A 2 GHz circuit incorporating this tuning element was also tested to demonstrate practical tuning ranges. This structure can be fabricated for frequencies as high as 1000 GHz using existing micromachining techniques. Many commercial applications can benefit from this micromechanical RF tuning element, as it will aid in extending microwave integrated circuit technology into the high millimeter wave and submillimeter wave bands by easing constraints on circuit technology.

  1. Integration Of The Security Sub-Modules Elements In The Automotive Industry

    International Nuclear Information System (INIS)

    Gallego, C.; Fernandez, M.; Caires, A. S.; Canibano, E.

    2007-01-01

    This study is addressed to obtain a design methodology for integrated security sub-modules (constituting the suspension and steering modules) in the car manufacturing industry. The sub-modules are made up of a steel structure and anchorage elements (rubber-metal or plastic-metal), which undergo separate surface treatments to prevent corrosion. Afterwards, the elements are traditionally joined by means of adhesives and screws. This process involves a great number of stages, low quality union methods and generation of corrosion areas that shorten its useful life.This methodology provides automotive suppliers an additional added value and cost reduction, allowing them to increase its competitiveness in a sector that faces the transition from the traditional supply chain to a strategic value chain

  2. Numerical simulation of experimental data from planar SIS mixers with integrated tuning elements

    International Nuclear Information System (INIS)

    Mears, C.A.; Hu, Qing; Richards, P.L.

    1988-08-01

    We have used the full Tucker theory including the quantum susceptance to fit data from planar lithographed mm-wave mixers with bow tie antennas and integrated RF coupling elements. Essentially perfect fits to pumped IV curves have been obtained. The deduced imbedding admittances agree well with those independently calculated from the geometry of the antenna and matching structures. We find that the quantum susceptance is essential to the fit and thus to predictions of the mixer performance. For junctions with moderately sharp gap structures, the quantum susceptance is especially important in the production of steps with low and/or negative dynamic conductance. 15 refs., 4 figs

  3. Number-conserving random phase approximation with analytically integrated matrix elements

    International Nuclear Information System (INIS)

    Kyotoku, M.; Schmid, K.W.; Gruemmer, F.; Faessler, A.

    1990-01-01

    In the present paper a number conserving random phase approximation is derived as a special case of the recently developed random phase approximation in general symmetry projected quasiparticle mean fields. All the occurring integrals induced by the number projection are performed analytically after writing the various overlap and energy matrices in the random phase approximation equation as polynomials in the gauge angle. In the limit of a large number of particles the well-known pairing vibration matrix elements are recovered. We also present a new analytically number projected variational equation for the number conserving pairing problem

  4. Monolithic nanoscale photonics-electronics integration in silicon and other group IV elements

    CERN Document Server

    Radamson, Henry

    2014-01-01

    Silicon technology is evolving rapidly, particularly in board-to-board or chip-to chip applications. Increasingly, the electronic parts of silicon technology will carry out the data processing, while the photonic parts take care of the data communication. For the first time, this book describes the merging of photonics and electronics in silicon and other group IV elements. It presents the challenges, the limitations, and the upcoming possibilities of these developments. The book describes the evolution of CMOS integrated electronics, status and development, and the fundamentals of silicon p

  5. The role of size constancy for the integration of local elements into a global shape

    Directory of Open Access Journals (Sweden)

    Johannes eRennig

    2013-07-01

    Full Text Available Visual perception depends on the visual context and is likely to be influenced by size constancy, which predicts a size and distance invariant perception of objects. However, size constancy can also result in optical illusions that allow the manipulation of the perceived size. We thus asked whether the integration of local elements into a global object can be influenced by manipulations of the visual context and size constancy? A set of stimuli was applied in healthy individuals that took advantage of the ‘Kanizsa’ illusion, in which three circles with open wedges oriented towards a center point are placed to form an illusionary perception of a triangle. In addition, a 3D-perspective view was implemented in which the global target (‘Kanizsa’ triangle was placed in combination with several distractor circles either in a close or a distant position. Subjects were engaged in a global recognition task on the location of the ‘Kanizsa’ triangle. Global recognition of ‘Kanizsa’ triangles improved with a decreasing length of the illusory contour. Interestingly, recognition of ‘Kanizsa’ triangles decreased when they were perceived as if they were located further away. We conclude that the integration of local elements into a global object is dependent on the visual context and dominated by size constancy.

  6. Transposable elements in fish chromosomes: a study in the marine cobia species.

    Science.gov (United States)

    Costa, G W W F; Cioffi, M B; Bertollo, L A C; Molina, W F

    2013-01-01

    Rachycentron canadum, a unique representative of the Rachycentridae family, has been the subject of considerable biotechnological interest due to its potential use in marine fish farming. This species has undergone extensive research concerning the location of genes and multigene families on its chromosomes. Although most of the genome of some organisms is composed of repeated DNA sequences, aspects of the origin and dispersion of these elements are still largely unknown. The physical mapping of repetitive sequences on the chromosomes of R. canadum proved to be relevant for evolutionary and applied purposes. Therefore, here, we present the mapping by fluorescence in situ hybridization of the transposable element (TE) Tol2, the non-LTR retrotransposons Rex1 and Rex3, together with the 18S and 5S rRNA genes in the chromosome of this species. The Tol2 TE, belonging to the family of hAT transposons, is homogeneously distributed in the euchromatic regions of the chromosomes but with huge colocalization with the 18S rDNA sites. The hybridization signals for Rex1 and Rex3 revealed a semi-arbitrary distribution pattern, presenting differentiated dispersion in euchromatic and heterochromatic regions. Rex1 elements are associated preferentially in heterochromatic regions, while Rex3 shows a scarce distribution in the euchromatic regions of the chromosomes. The colocalization of TEs with 18S and 5S rDNA revealed complex chromosomal regions of repetitive sequences. In addition, the nonpreferential distribution of Rex1 and Rex3 in all heterochromatic regions, as well as the preferential distribution of the Tol2 transposon associated with 18S rDNA sequences, reveals a distinct pattern of organization of TEs in the genome of this species. A heterogeneous chromosomal colonization of TEs may confer different evolutionary rates to the heterochromatic regions of this species.

  7. Textile antenna integrated with compact AMC and parasitic elements for WLAN/WBAN applications

    Science.gov (United States)

    Lago, Herwansyah; Soh, Ping Jack; Jamlos, Mohd Faizal; Shohaimi, Nursuriati; Yan, Sen; Vandenbosch, Guy A. E.

    2016-12-01

    A wearable antenna fully designed and fabricated using textile is presented. Both antenna and artificial magnetic conductor plane are designed for operation in the wireless local area network (WLAN)/wireless body area network (WBAN) band from 2.4 to 2.5 GHz. The AMC unit element is designed based on the rectangular patch structure, which is then integrated using slots and slits for bandwidth broadening. Meanwhile, the combination of the slits and L-shaped parasitic elements applied at four edges of the rectangular antenna structure enabled unidirectional radiation outwards from the body. The structure is coaxially fed using a rectangular ring slot centered on the radiating element. Simulated and measured reflection and radiation performance indicate a satisfactory agreement, fulfilling the requirements for WLAN/WBAN applications both in free space and on body. The shielding effectiveness provided by the AMC plane is also evaluated numerically in terms of specific absorption rate, indicating levels below the European regulatory limit of 2 W/kg.

  8. Infill architecture: Design approaches for in-between buildings and 'bond' as integrative element

    Directory of Open Access Journals (Sweden)

    Alfirević Đorđe

    2015-01-01

    Full Text Available The aim of the paper is to draw attention to the view that the two key elements in achieving good quality of architecture infill in immediate, current surroundings, are the selection of optimal creative method of infill architecture and adequate application of 'the bond' as integrative element, The success of achievement and the quality of architectural infill mainly depend on the assessment of various circumstances, but also on the professionalism, creativity, sensibility, and finally innovativeness of the architect, In order for the infill procedure to be carried out adequately, it is necessary to carry out the assessment of quality of the current surroundings that the object will be integrated into, and then to choose the creative approach that will allow the object to establish an optimal dialogue with its surroundings, On a wider scale, both theory and the practice differentiate thee main creative approaches to infill objects: amimetic approach (mimesis, bassociative approach and ccontrasting approach, Which of the stated approaches will be chosen depends primarily on the fact whether the existing physical structure into which the object is being infilled is 'distinct', 'specific' or 'indistinct', but it also depends on the inclination of the designer, 'The bond' is a term which in architecture denotes an element or zone of one object, but in some instances it can refer to the whole object which has been articulated in a specific way, with an aim of reaching the solution for the visual conflict as is often the case in situations when there is a clash between the existing objects and the newly designed or reconstructed object, This paper provides in-depth analysis of different types of bonds, such as 'direction as bond', 'cornice as bond', 'structure as bond', 'texture as bond' and 'material as bond', which indicate complexity and multiple layers of the designing process of object interpolation.

  9. Application of the integral method to modelling the oxidation of defected fuel elements

    International Nuclear Information System (INIS)

    Kolar, M.

    1995-06-01

    The starting point for this report is the discrepancy reported in previous work between the reaction-diffusion calculations and the CEX-1 experiment, which involves storage of defected fuel elements in air at 150 deg C. This discrepancy is considerably diminished here by a more critical choice of theoretical parameters, and by taking into account the fact that different CEX-1 fuel elements were oxidized at very different rates and that the fuel element used previously for comparison with theoretical calculations actually underwent two limited-oxygen-supply cycles. Much better agreement is obtained here between the theory and the third, unlimited-air, storage period of the CEX-1 experiment. The approximate integral method is used extensively for the solution of the one-dimensional diffusion moving-boundary problems that may describe various storage periods of the CEX-1 experiment. In some cases it is easy to extend this method to arbitrary precision by using higher moments of the diffusion equation. Using this method, the validity of quasi-steady-state approximation is verified. Diffusion-controlled oxidation is also studied. In this case, for the unlimited oxygen supply, the integral method leads to an exact analytical solution for linear geometry, and to a good analytical approximation of the solution for the spherically symmetric geometry. These solutions may have some application in the analysis of experiments on the oxidation of small UO 2 fragments or powders when the individual UO 2 grains may be considered to be approximately spherical. (author). 23 refs., 5 tabs., 11 figs

  10. The development of a volume element model for energy systems engineering and integrative thermodynamic optimization

    Science.gov (United States)

    Yang, Sam

    The dissertation presents the mathematical formulation, experimental validation, and application of a volume element model (VEM) devised for modeling, simulation, and optimization of energy systems in their early design stages. The proposed model combines existing modeling techniques and experimental adjustment to formulate a reduced-order model, while retaining sufficient accuracy to serve as a practical system-level design analysis and optimization tool. In the VEM, the physical domain under consideration is discretized in space using lumped hexahedral elements (i.e., volume elements), and the governing equations for the variable of interest are applied to each element to quantify diverse types of flows that cross it. Subsequently, a system of algebraic and ordinary differential equations is solved with respect to time and scalar (e.g., temperature, relative humidity, etc.) fields are obtained in both spatial and temporal domains. The VEM is capable of capturing and predicting dynamic physical behaviors in the entire system domain (i.e., at system level), including mutual interactions among system constituents, as well as with their respective surroundings and cooling systems, if any. The VEM is also generalizable; that is, the model can be easily adapted to simulate and optimize diverse systems of different scales and complexity and attain numerical convergence with sufficient accuracy. Both the capability and generalizability of the VEM are demonstrated in the dissertation via thermal modeling and simulation of an Off-Grid Zero Emissions Building, an all-electric ship, and a vapor compression refrigeration (VCR) system. Furthermore, the potential of the VEM as an optimization tool is presented through the integrative thermodynamic optimization of a VCR system, whose results are used to evaluate the trade-offs between various objective functions, namely, coefficient of performance, second law efficiency, pull-down time, and refrigerated space temperature, in

  11. Standard integral table algebras generated by non-real element of small degree

    CERN Document Server

    Muzychuk, Mikhail

    2002-01-01

    This book is addressed to the researchers working in the theory of table algebras and association schemes. This area of algebraic combinatorics has been rapidly developed during the last decade. The volume contains further developments in the theory of table algebras. It collects several papers which deal with a classification problem for standard integral table algebras (SITA). More precisely, we consider SITA with a faithful non-real element of small degree. It turns out that such SITA with some extra conditions may be classified. This leads to new infinite series of SITA which has interesting properties. The last section of the book uses a part of obtained results in the classification of association schemes. This volume summarizes the research which was done at Bar-Ilan University in the academic year 1998/99.

  12. Grassmann integral and Balian–Brézin decomposition in Hartree–Fock–Bogoliubov matrix elements

    Energy Technology Data Exchange (ETDEWEB)

    Mizusaki, Takahiro, E-mail: mizusaki@isc.senshu-u.ac.jp [Institute of Natural Sciences, Senshu University, 3-8-1 Kanda-Jinbocho, Chiyoda-ku, Tokyo 101-8425 (Japan); Oi, Makito [Institute of Natural Sciences, Senshu University, 3-8-1 Kanda-Jinbocho, Chiyoda-ku, Tokyo 101-8425 (Japan); Chen, Fang-Qi [Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai 200240 (China); Sun, Yang [Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai 200240 (China); Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China)

    2013-08-09

    We present a new formula to calculate matrix elements of a general unitary operator with respect to Hartree–Fock–Bogoliubov states allowing multiple quasi-particle excitations. The Balian–Brézin decomposition of the unitary operator [R. Balian, E. Brézin, Il Nuovo Cimento B 64 (1969) 37] is employed in the derivation. We found that this decomposition is extremely suitable for an application of Fermion coherent state and Grassmann integrals in the quasi-particle basis. The resultant formula is compactly expressed in terms of the Pfaffian, and shows the similar bipartite structure to the formula that we have previously derived in the bare-particles basis [T. Mizusaki, M. Oi, Phys. Lett. B 715 (2012) 219].

  13. Finite-element blunt-crack propagation: a modified J-integral approach

    International Nuclear Information System (INIS)

    Pan, Y.C.; Marchertas, A.H.; Kennedy, J.M.

    1983-01-01

    In assessing the safety of a liquid metal fast breeder reactor (LMFBR), a major concern is the behavior of concrete structures subjected to high temperatures. The potential of concrete cracking is an important parameter which could significantly influence the safety assessment of thermally attacked concrete. A new modified J-integral approach for the blunt crack model has been derived to provide a general procedure to accurately predict the direction of crack growth. This formulation has been incorporated into the coupled heat transfer-stress analysis finite element code TEMP-STRESS. A description of the formulation is presented in this paper. Results for the problems of a Mode I and mixed mode crack in a plate using regular and slanted meshes subjected to uniaxial and shear loading are presented

  14. Precise integration of inducible transcriptional elements (PrIITE) enables absolute control of gene expression

    DEFF Research Database (Denmark)

    Pinto, Rita; Hansen, Lars; Hintze, John

    2017-01-01

    to be a limitation. Here, we report that the combined use of genome editing tools and last generation Tet-On systems can resolve these issues. Our principle is based on precise integration of inducible transcriptional elements (coined PrIITE) targeted to: (i) exons of an endogenous gene of interest (GOI) and (ii......Tetracycline-based inducible systems provide powerful methods for functional studies where gene expression can be controlled. However, the lack of tight control of the inducible system, leading to leakiness and adverse effects caused by undesirable tetracycline dosage requirements, has proven......) a safe harbor locus. Using PrIITE cells harboring a GFP reporter or CDX2 transcription factor, we demonstrate discrete inducibility of gene expression with complete abrogation of leakiness. CDX2 PrIITE cells generated by this approach uncovered novel CDX2 downstream effector genes. Our results provide...

  15. Energy balance of photovoltaic elements integrated in buildings; Energiebilanz gebaeudeintegrierter Photovoltaik

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    A planning tool for the thermal characteristics of integrated PV modules was to be developed and validated by measurements which provides U and g values as well as heating and cooling loads of such external wall or roof elements. In a cooperative project with medium-sized producers of PV wall systems, two different wall systems (i.e. insulating glass and ventilated warm external walls) were analyzed. [German] In dem Forschungsvorhaben sollte ein messtechnisch validiertes Planungswerkzeug fuer die thermischen Kennwerte von gebaeudeintegrierten Photovoltaikmodulen entwickelt werden, welches Bauteilkennwerte (U- und g-Werte) sowie moegliche Heiz- und Kuehllasten solcher Fassaden- oder Dachsysteme liefert. Durch die Zusammenarbeit mit mittelstaendischen PV-Fassadenherstellern sollten zwei Fassadensysteme - Isolierglasverbund und hinterlueftete Warmfassade - an konkreten Projekten messtechnisch erfasst und analysiert werden. (orig.)

  16. Criteria for the selection of graphites for HTR integral block fuel elements

    International Nuclear Information System (INIS)

    Knowles, A.N.

    1980-01-01

    This paper is concerned with the special requirements for integral block fuel elements of the type first used in the Fort St. Vrain reactor. The main idea of these elements is that the carrier block and separate graphite clad fuel pins are combined into a single monolith. This combination leads to lower fabrication costs and some improvement in the thermal performance (lower temperature difference between fuel and the surface of heat transfer into the coolant). The advent of block fuel for HTRs of the Fort St. Vrain type has placed a fresh emphasis on the selection of graphite for block manufacture in respect of physical properties. This is because the temperature distributions typical of such fuelled blocks lead to shutdown stresses close to the maximum the graphite can sustain without damage. Figures presented in this paper suggest that the physical properties of the graphite can play a relatively large part in reducing such stress levels and that guidance on the key requirements for suitable specifications is therefore particularly needed by the manufacturers of fuel block graphites. While graphites for fuel blocks have this special need for combinations of physical properties which lead to low thermal and shrinkage stresses, the other characteristics must also receive attention. A low graphite cost combined with good homogeneity in the brick, so that waste minimized, are still necessary, while isotropy is also very important

  17. In situ 3D nanoprinting of free-form coupling elements for hybrid photonic integration

    Science.gov (United States)

    Dietrich, P.-I.; Blaicher, M.; Reuter, I.; Billah, M.; Hoose, T.; Hofmann, A.; Caer, C.; Dangel, R.; Offrein, B.; Troppenz, U.; Moehrle, M.; Freude, W.; Koos, C.

    2018-04-01

    Hybrid photonic integration combines complementary advantages of different material platforms, offering superior performance and flexibility compared with monolithic approaches. This applies in particular to multi-chip concepts, where components can be individually optimized and tested. The assembly of such systems, however, requires expensive high-precision alignment and adaptation of optical mode profiles. We show that these challenges can be overcome by in situ printing of facet-attached beam-shaping elements. Our approach allows precise adaptation of vastly dissimilar mode profiles and permits alignment tolerances compatible with cost-efficient passive assembly techniques. We demonstrate a selection of beam-shaping elements at chip and fibre facets, achieving coupling efficiencies of up to 88% between edge-emitting lasers and single-mode fibres. We also realize printed free-form mirrors that simultaneously adapt beam shape and propagation direction, and we explore multi-lens systems for beam expansion. The concept paves the way to automated assembly of photonic multi-chip systems with unprecedented performance and versatility.

  18. Translating the Elements of Health Governance for Integrated Care from Theory to Practice: A Case Study Approach.

    Science.gov (United States)

    Nicholson, Caroline; Hepworth, Julie; Burridge, Letitia; Marley, John; Jackson, Claire

    2018-01-31

    Against a paucity of evidence, a model describing elements of health governance best suited to achieving integrated care internationally was developed. The aim of this study was to explore how health meso-level organisations used, or planned to use, the governance elements. A case study design was used to offer two contrasting contexts of health governance. Semi-structured interviews were conducted with participants who held senior governance roles. Data were thematically analysed to identify if the elements of health governance were being used, or intended to be in the future. While all participants agreed that the ten elements were essential to developing future integrated care, most were not used. Three major themes were identified: (1) organisational versus system focus, (2) leadership and culture, and, (3) community (dis)engagement. Several barriers and enablers to the use of the elements were identified and would require addressing in order to make evidence-based changes. Despite a clear international policy direction in support of integrated care this study identified a number of significant barriers to its implementation. The study reconfirmed that a focus on all ten elements of health governance is essential to achieve integrated care.

  19. Study of thermal performance of capillary micro tubes integrated into the building sandwich element made of high performance concrete

    DEFF Research Database (Denmark)

    Mikeska, Tomas; Svendsen, Svend

    2013-01-01

    The thermal performance of radiant heating and cooling systems (RHCS) composed of capillary micro tubes (CMT) integrated into the inner plate of sandwich elements made of high performance concrete (HPC) was investigated in the article. Temperature distribution in HPC elements around integrated CM...... and cooling purposes of future low energy buildings. The investigations were conceived as a low temperature concept, where the difference between the temperature of circulating fluid and air in the room was kept in range of 1–4 °C.......The thermal performance of radiant heating and cooling systems (RHCS) composed of capillary micro tubes (CMT) integrated into the inner plate of sandwich elements made of high performance concrete (HPC) was investigated in the article. Temperature distribution in HPC elements around integrated CMT...... HPC layer covering the CMT. This paper shows that CMT integrated into the thin plate of sandwich element made of HPC can supply the energy needed for heating (cooling) and at the same time create the comfortable and healthy environment for the occupants. This solution is very suitable for heating...

  20. Finite element modelling of process-integrated powder coating by radial axial rolling of rings

    International Nuclear Information System (INIS)

    Frischkorn, J.; Kebriaei, R.; Reese, S.; Moll, H.; Theisen, W.; Husmann, T.; Meier, H.

    2011-01-01

    The process-integrated powder coating by radial axial rolling of rings represents a new hybrid production technique applied in the manufacturing of large ring-shaped work pieces with functional layers. It is thought to break some limitations that come along with the hot isostatic pressing (HIP) which is used nowadays to apply the powdery layer material onto the rolled substrate ring. Within the new process the compaction of the layer material is integrated into the ring rolling and HIP becomes dispensable. Following this approach the rolling of such compound rings brings up some new challenges. The volume of a solid ring stays nearly constant during the rolling. This behaviour can be exploited to determine the infeed of the rollers needed to reach the desired ring shape. Since volume consistency cannot be guaranteed for the rolling of a compound ring the choice of appropriate infeed of the rollers is still an open question. This paper deals with the finite element (FE) simulation of this new process. First, the material model that is used to describe the compaction of the layer material is shortly reviewed. The main focus of the paper is then put on a parameterized FE ring rolling model that incorporates a control system in order to stabilize the process. Also the differences in the behaviour during the rolling stage between a compound and a solid ring will be discussed by means of simulation results.

  1. True Concurrent Thermal Engineering Integrating CAD Model Building with Finite Element and Finite Difference Methods

    Science.gov (United States)

    Panczak, Tim; Ring, Steve; Welch, Mark

    1999-01-01

    Thermal engineering has long been left out of the concurrent engineering environment dominated by CAD (computer aided design) and FEM (finite element method) software. Current tools attempt to force the thermal design process into an environment primarily created to support structural analysis, which results in inappropriate thermal models. As a result, many thermal engineers either build models "by hand" or use geometric user interfaces that are separate from and have little useful connection, if any, to CAD and FEM systems. This paper describes the development of a new thermal design environment called the Thermal Desktop. This system, while fully integrated into a neutral, low cost CAD system, and which utilizes both FEM and FD methods, does not compromise the needs of the thermal engineer. Rather, the features needed for concurrent thermal analysis are specifically addressed by combining traditional parametric surface based radiation and FD based conduction modeling with CAD and FEM methods. The use of flexible and familiar temperature solvers such as SINDA/FLUINT (Systems Improved Numerical Differencing Analyzer/Fluid Integrator) is retained.

  2. STARS: An Integrated, Multidisciplinary, Finite-Element, Structural, Fluids, Aeroelastic, and Aeroservoelastic Analysis Computer Program

    Science.gov (United States)

    Gupta, K. K.

    1997-01-01

    A multidisciplinary, finite element-based, highly graphics-oriented, linear and nonlinear analysis capability that includes such disciplines as structures, heat transfer, linear aerodynamics, computational fluid dynamics, and controls engineering has been achieved by integrating several new modules in the original STARS (STructural Analysis RoutineS) computer program. Each individual analysis module is general-purpose in nature and is effectively integrated to yield aeroelastic and aeroservoelastic solutions of complex engineering problems. Examples of advanced NASA Dryden Flight Research Center projects analyzed by the code in recent years include the X-29A, F-18 High Alpha Research Vehicle/Thrust Vectoring Control System, B-52/Pegasus Generic Hypersonics, National AeroSpace Plane (NASP), SR-71/Hypersonic Launch Vehicle, and High Speed Civil Transport (HSCT) projects. Extensive graphics capabilities exist for convenient model development and postprocessing of analysis results. The program is written in modular form in standard FORTRAN language to run on a variety of computers, such as the IBM RISC/6000, SGI, DEC, Cray, and personal computer; associated graphics codes use OpenGL and IBM/graPHIGS language for color depiction. This program is available from COSMIC, the NASA agency for distribution of computer programs.

  3. Phylogeographic diversity and mosaicism of the Helicobacter pylori tfs integrative and conjugative elements.

    Science.gov (United States)

    Delahay, Robin M; Croxall, Nicola J; Stephens, Amberley D

    2018-01-01

    The genome of the gastric pathogen Helicobacter pylori is characterised by considerable variation of both gene sequence and content, much of which is contained within three large genomic islands comprising the cag pathogenicity island ( cag PAI) and two mobile integrative and conjugative elements (ICEs) termed tfs3 and tfs4 . All three islands are implicated as virulence factors, although whereas the cag PAI is well characterised, understanding of how the tfs elements influence H. pylori interactions with different human hosts is significantly confounded by limited definition of their distribution, diversity and structural representation in the global H. pylori population. To gain a global perspective of tfs ICE population dynamics we established a bioinformatics workflow to extract and precisely define the full tfs pan-gene content contained within a global collection of 221 draft and complete H. pylori genome sequences. Complete (ca. 35-55kbp) and remnant tfs ICE clusters were reconstructed from a dataset comprising > 12,000 genes, from which orthologous gene complements and distinct alleles descriptive of different tfs ICE types were defined and classified in comparative analyses. The genetic variation within defined ICE modular segments was subsequently used to provide a complete description of tfs ICE diversity and a comprehensive assessment of their phylogeographic context. Our further examination of the apparent ICE modular types identified an ancient and complex history of ICE residence, mobility and interaction within particular H. pylori phylogeographic lineages and further, provided evidence of both contemporary inter-lineage and inter-species ICE transfer and displacement. Our collective results establish a clear view of tfs ICE diversity and phylogeographic representation in the global H. pylori population, and provide a robust contextual framework for elucidating the functional role of the tfs ICEs particularly as it relates to the risk of gastric

  4. Dimensional measurements and eddy currents control of the sheath integrity for a set of irradiated candu fuel elements

    International Nuclear Information System (INIS)

    Gheorghe, G.; Man, I.

    2015-01-01

    During irradiation in the nuclear reactor, fuel elements undergo dimensional and structural changes, and changes of sheath surface condition as well, which can lead to damages and even loss of integrity. This paper presents the results of dimensional measurements and of examination technique with eddy currents for three fuel elements of an irradiated CANDU fuel bundle. One of the fuel elements (FE), which is studied in detail, presented a crack about 40 mm long. The purpose of these nondestructive examination techniques is to determine those parameters that characterize the behavior and performance of nuclear fuel operation. This paper contains images of defects and interpretations of the causes of their occurrence. (authors)

  5. Linear pulse motor type control element drive mechanism for the integral reactor

    International Nuclear Information System (INIS)

    Yu, J. Y.; Choi, S.; Kim, J. H.; Huh, H.; Park, K. B.

    2007-01-01

    The integral reactor SMART currently under development at Korea Atomic Energy Research Institute is designed with soluble boron free operation and use of nuclear heating for reactor startup. These design features require the Control Element Drive Mechanism (CEDM) for SMART to have fine-step movement capability as well as high reliability for the fine reactivity control. In this paper, design characteristics of a new concept CEDM driven by the Linear Pulse Motor (LPM) which meets the design requirements of the integral reactor SMART are introduced. The primary dimensions of the linear pulse motor are determined by the electro-magnetic analysis and the results are also presented. In parallel with the electro-magnetic analysis, the conceptual design of the CEDM is visualized and checked for interferences among parts by assembling three dimensional (3D) models on the computer. Prototype of LPM with double air-gaps for the CEDM sub-assemblies to lift 100 kg is designed, analysed, manufactured and tested to confirm the validity of the CEDM design concept. A converter and a test facility are manufactured to verify the dynamic performance of the LPM. The mover of the LPM is welded with ferromagnetic material and non-ferromagnetic material to get the magnetic flux path between inner stator and outer stator. The thrust forces of LPM predicted by analytic model have shown good agreement with experimental results from the prototype LPM. It is found that the LPM type CEDM has high force density and simple drive mechanism to reduce volume and satisfy the reactor operating circumstances with high pressure and temperature

  6. Integrated Project Teams - An Essential Element of Project Management during Project Planning and Execution - 12155

    Energy Technology Data Exchange (ETDEWEB)

    Burritt, James G.; Berkey, Edgar [Longenecker and Associates, Las Vegas, NV 89135 (United States)

    2012-07-01

    Managing complex projects requires a capable, effective project manager to be in place, who is assisted by a team of competent assistants in various relevant disciplines. This team of assistants is known as the Integrated Project Team (IPT). he IPT is composed of a multidisciplinary group of people who are collectively responsible for delivering a defined project outcome and who plan, execute, and implement over the entire life-cycle of a project, which can be a facility being constructed or a system being acquired. An ideal IPT includes empowered representatives from all functional areas involved with a project-such as engineering design, technology, manufacturing, test and evaluation, contracts, legal, logistics, and especially, the customer. Effective IPTs are an essential element of scope, cost, and schedule control for any complex, large construction project, whether funded by DOE or another organization. By recently assessing a number of major, on-going DOE waste management projects, the characteristics of high performing IPTs have been defined as well as the reasons for potential IPT failure. Project managers should use IPTs to plan and execute projects, but the IPTs must be properly constituted and the members capable and empowered. For them to be effective, the project manager must select the right team, and provide them with the training and guidance for them to be effective. IPT members must treat their IPT assignment as a primary duty, not some ancillary function. All team members must have an understanding of the factors associated with successful IPTs, and the reasons that some IPTs fail. Integrated Project Teams should be used by both government and industry. (authors)

  7. Current status of the transient integral fuel element performance code URANUS

    International Nuclear Information System (INIS)

    Preusser, T.; Lassmann, K.

    1983-01-01

    To investigate the behavior of fuel pins during normal and off-normal operation, the integral fuel rod code URANUS has been extended to include a transient version. The paper describes the current status of the program system including a presentation of newly developed models for hypothetical accident investigation. The main objective of current development work is to improve the modelling of fuel and clad material behavior during fast transients. URANUS allows detailed analysis of experiments until the onset of strong material transport phenomena. Transient fission gas analysis is carried out due to the coupling with a special version of the LANGZEIT-KURZZEIT-code (KfK). Fuel restructuring and grain growth kinetics models have been improved recently to better characterize pre-experimental steady-state operation; transient models are under development. Extensive verification of the new version has been carried out by comparison with analytical solutions, experimental evidence, and code-to-code evaluation studies. URANUS, with all these improvements, has been successfully applied to difficult fast breeder fuel rod analysis including TOP, LOF, TUCOP, local coolant blockage and specific carbide fuel experiments. Objective of further studies is the description of transient PCMI. It is expected that the results of these developments will contribute significantly to the understanding of fuel element structural behavior during severe transients. (orig.)

  8. Integration of growth factor signals at the c-fos serum response element.

    Science.gov (United States)

    Price, M A; Hill, C; Treisman, R

    1996-04-29

    A transcription factor ternary complex composed of serum response factor (SRF) and a second factor, ternary complex factor (TCF), mediates the response of the c-fos Serum Response Element to growth factors and mitogens. In NIH3T3 fibroblasts, TCF binding is required for transcriptional activation by the SRE in response to activation of the Ras-Raf-ERK pathway. We compared the properties of three members of the TCF family, Elk-1, SAP-1 and SAP-2 (ERP/NET). Although all the proteins contain sequences required for ternary complex formation with SRF, only Elk-1 and SAP-1 appear to interact with the c-fos SRE efficiently in vivo. Each TCF contains a C-terminal activation domain capable of transcriptional activation in response to activation of the Ras-Raf-ERK pathway, and this is dependent on the integrity of S/T-P motifs conserved between all the TCF family members. In contrast, activation of the SRE by whole serum and the mitogenic phospholipid LPA requires SRF binding alone. Constitutively activated members of the Rho subfamily of Ras-like GTPases are also capable of inducing activation of the SRE in the absence of TCF; unlike activated Ras itself, these proteins do not activate the TCFs in NIH3T3 cells. At the SRE, SRF- and TCF-linked signalling pathways act synergistically to potentiate transcription.

  9. A time-domain finite element boundary integral approach for elastic wave scattering

    Science.gov (United States)

    Shi, F.; Lowe, M. J. S.; Skelton, E. A.; Craster, R. V.

    2018-04-01

    The response of complex scatterers, such as rough or branched cracks, to incident elastic waves is required in many areas of industrial importance such as those in non-destructive evaluation and related fields; we develop an approach to generate accurate and rapid simulations. To achieve this we develop, in the time domain, an implementation to efficiently couple the finite element (FE) method within a small local region, and the boundary integral (BI) globally. The FE explicit scheme is run in a local box to compute the surface displacement of the scatterer, by giving forcing signals to excitation nodes, which can lie on the scatterer itself. The required input forces on the excitation nodes are obtained with a reformulated FE equation, according to the incident displacement field. The surface displacements computed by the local FE are then projected, through time-domain BI formulae, to calculate the scattering signals with different modes. This new method yields huge improvements in the efficiency of FE simulations for scattering from complex scatterers. We present results using different shapes and boundary conditions, all simulated using this approach in both 2D and 3D, and then compare with full FE models and theoretical solutions to demonstrate the efficiency and accuracy of this numerical approach.

  10. The Four-Element Framework: An Integrated Test and Evaluation Strategy

    National Research Council Canada - National Science Library

    Wilcox, Christopher M

    2007-01-01

    ...) planning and execution. Process is comprised of four elements: 1) Operational View (OV) - mission tasks, activities, operational elements and information required to accomplish warfighting mission. 2) System View (SV...

  11. Comparison of finite element J-integral evaluations for the blunt crack model and the sharp crack model

    International Nuclear Information System (INIS)

    Pan, Y.C.; Kennedy, J.M.

    1983-01-01

    In assessing the safety of a liquid metal fast breeder reactor (LMFBR), a major concern is that of hot sodium coming into contact with either unprotected concrete or steel-lined concrete equipment cells and containment structures. An aspect of this is the potential of concrete cracking which would significantly influence the safety assessment. Concrete cracking in finite element analysis can be modeled as a blunt crack in which the crack is assumed to be uniformly distributed throughout the area of the element. A blunt crack model based on the energy release rate and the effective strength concepts which was insensitive to the element size was presented by Bazant and Cedolin. Some difficulties were encountered in incorporating their approach into a general purpose finite element code. An approach based on the J-integral to circumvent some of the difficulties was proposed by Pan, Marchertas, and Kennedy. Alternatively, cracking can also be modeled as a sharp crack where the crack surface is treated as the boundary of the finite element mesh. The sharp crack model is adopted by most researchers and its J-integral has been well established. It is desirable to establish the correlation between the J-integrals, or the energy release rates, for the blunt crack model and the sharp crack model so that data obtained from one model can be used on the other

  12. 3-D Imaging Using Row–Column-Addressed Arrays With Integrated Apodization. Part I: Apodization Design and Line Element Beamforming

    DEFF Research Database (Denmark)

    Rasmussen, Morten Fischer; Christiansen, Thomas Lehrmann; Thomsen, Erik Vilain

    2015-01-01

    -integrated apodization increased the apparent diameter of the vessel from 2.0 mm to 2.4 mm, corresponding to an increase from 67% to 80% of the true vessel diameter. The line element beamforming approach is shown to be essential for achieving correct time-of-flight calculations, and hence avoid geometrical distortions...

  13. Portable waveguide display system with a large field of view by integrating freeform elements and volume holograms.

    Science.gov (United States)

    Han, Jian; Liu, Juan; Yao, Xincheng; Wang, Yongtian

    2015-02-09

    A compact waveguide display system integrating freeform elements and volume holograms is presented here for the first time. The use of freeform elements can broaden the field of view, which limits the applications of a holographic waveguide. An optimized system can achieve a diagonal field of view of 45° when the thickness of the waveguide planar is 3mm. Freeform-elements in-coupler and the volume holograms out-coupler were designed in detail in our study, and the influence of grating configurations on diffraction efficiency was analyzed thoroughly. The off-axis aberrations were well compensated by the in-coupler and the diffraction efficiency of the optimized waveguide display system could reach 87.57%. With integrated design, stability and reliability of this monochromatic display system were achieved and the alignment of the system was easily controlled by the record of the volume holograms, which makes mass production possible.

  14. On the integration of computer aided design and analysis using the finite element absolute nodal coordinate formulation

    International Nuclear Information System (INIS)

    Sanborn, Graham G.; Shabana, Ahmed A.

    2009-01-01

    For almost a decade, the finite element absolute nodal coordinate formulation (ANCF) has been used for both geometry and finite element representations. Because of the ANCF isoparametric property in the cases of beams, plates and shells, ANCF finite elements lend themselves easily to the geometric description of curves and surfaces, as demonstrated in the literature. The ANCF finite elements, therefore, are ideal for what is called isogeometric analysis that aims at the integration ofcomputer aided designandanalysis (ICADA), which involves the integration of what is now split into the separate fields of computer aided design (CAD) and computer aided analysis (CAA). The purpose of this investigation is to establish the relationship between the B-spline and NURBS, which are widely used in the geometric modeling, and the ANCF finite elements. It is shown in this study that by using the ANCF finite elements, one can in a straightforward manner obtain the control point representation required for the Bezier, B-spline and NURBS geometry. To this end, a coordinate transformation is used to write the ANCF gradient vectors in terms of control points. Unifying the CAD and CAA will require the use of such coordinate transformations and their inverses in order to transform control points to position vector gradients which are required for the formulation of the element transformations in the case of discontinuities as well as the formulation of the strain measures and the stress forces based on general continuum mechanics theory. In particular, fully parameterized ANCF finite elements can be very powerful in describing curve, surface, and volume geometry, and they can be effectively used to describe discontinuities while maintaining the many ANCF desirable features that include a constant mass matrix, zero Coriolis and centrifugal forces, no restriction on the amount of rotation or deformation within the finite element, ability for straightforward implementation of general

  15. Adaptive Kronrod-Patterson integration of non-linear finite-element matrices

    DEFF Research Database (Denmark)

    Janssen, Hans

    2010-01-01

    inappropriate discretization. In response, this article develops adaptive integration, based on nested Kronrod-Patterson-Gauss integration schemes: basically, the integration order is adapted to the locally observed grade of non-linearity. Adaptive integration is developed based on a standard infiltration...

  16. The SMART Theory and Modeling Team: An Integrated Element of Mission Development and Science Analysis

    Science.gov (United States)

    Hesse, Michael; Birn, J.; Denton, Richard E.; Drake, J.; Gombosi, T.; Hoshino, M.; Matthaeus, B.; Sibeck, D.

    2005-01-01

    When targeting physical understanding of space plasmas, our focus is gradually shifting away from discovery-type investigations to missions and studies that address our basic understanding of processes we know to be important. For these studies, theory and models provide physical predictions that need to be verified or falsified by empirical evidence. Within this paradigm, a tight integration between theory, modeling, and space flight mission design and execution is essential. NASA's Magnetospheric MultiScale (MMS) mission is a pathfinder in this new era of space research. The prime objective of MMS is to understand magnetic reconnection, arguably the most fundamental of plasma processes. In particular, MMS targets the microphysical processes, which permit magnetic reconnection to operate in the collisionless plasmas that permeate space and astrophysical systems. More specifically, MMS will provide closure to such elemental questions as how particles become demagnetized in the reconnection diffusion region, which effects determine the reconnection rate, and how reconnection is coupled to environmental conditions such as magnetic shear angles. Solutions to these problems have remained elusive in past and present spacecraft missions primarily due to instrumental limitations - yet they are fundamental to the large-scale dynamics of collisionless plasmas. Owing to the lack of measurements, most of our present knowledge of these processes is based on results from modern theory and modeling studies of the reconnection process. Proper design and execution of a mission targeting magnetic reconnection should include this knowledge and have to ensure that all relevant scales and effects can be resolved by mission measurements. The SMART mission has responded to this need through a tight integration between instrument and theory and modeling teams. Input from theory and modeling is fed into all aspects of science mission design, and theory and modeling activities are tailored

  17. Effect of Integration Patterns Around Implant Neck on Stress Distribution in Peri-Implant Bone: A Finite Element Analysis.

    Science.gov (United States)

    Han, Jingyun; Sun, Yuchun; Wang, Chao

    2017-08-01

    To investigate the biomechanical performance of different osseointegration patterns between cortical bone and implants using finite element analysis. Fifteen finite element models were constructed of the mandibular fixed prosthesis supported by implants. Masticatory loads (200 N axial, 100 N oblique, 40 N horizontal) were applied. The cortical bone/implant interface was divided equally into four layers: upper, upper-middle, lower-middle, and lower. The bone stress and implant displacement were calculated for 5 degrees of uniform integration (0, 20%, 40%, 60%, and 100%) and 10 integration patterns. The stress was concentrated in the bone margin and gradually decreased as osseointegration progressed, when the integrated and nonintegrated areas were alternated on the bone-implant surface. Compared with full integration, the integration of only the lower-middle layer or lower half layers significantly decreased von Mises, tensile, and compressive stresses in cortical bone under oblique and horizontal loads, and these patterns did not induce higher stress in the cancellous bone. For the integration of only the upper or upper-middle layer, stress in the cortical and cancellous bones significantly increased and was considerably higher than in the case of nonintegration. In addition, the maximum stress in the cortical bone was sensitive to the quantity of integrated nodes at the bone margin; lower quantity was associated with higher stress. There was no significant difference in the displacement of implants among 15 models. Integration patterns of cortical bone significantly affect stress distribution in peri-implant bone. The integration of only the lower-middle or lower half layers helps to increase the load-bearing capacity of peri-implant bone and decrease the risk of overloading, while upper integration may further increase the risk of bone resorption. © 2016 by the American College of Prosthodontists.

  18. Molecular analysis of an integrative conjugative element, ICEH, present in the chromosome of different strains of Mycoplasma hyopneumoniae

    Directory of Open Access Journals (Sweden)

    Paulo Marcos Pinto

    2007-01-01

    Full Text Available Diversification of bacterial species and pathotypes is largely caused by lateral gene transfer (LGT of diverse mobile DNA elements such as plasmids, phages, transposons and genomic islands. Thus, acquisition of new phenotypes by LGT is very important for bacterial evolution and relationship with hosts. This paper reports a 23 kb region containing fourteen CDSs with similarity to the previous described Integrative Conjugal Element of Mycoplasma fermentans (ICEF. This element, named ICEH, is present as one copy at distinct integration sites in the chromosome of 7448 and 232 pathogenic strains and is absent in the type strain J (non-pathogenic. Notable differences in the nucleotide composition of the insertion sites were detected, and could be correlated to a lack of specificity of the ICEH integrase. Although present in strains of the same organism, the ICEH elements are more divergent than the typical similarity between other chromosomal locus of Mycoplasma hyopneunomiae, suggesting an accelerated evolution of these constins or an ongoing process of degeneration, while maintaining conservation of the tra genes. An extrachromosomal form of this element had been detected in the 7448 strain, suggesting a possible involvement in its mobilization and transference of CDSs to new hosts.

  19. Identification of a Single Strand Origin of Replication in the Integrative and Conjugative Element ICEBs1 of Bacillus subtilis.

    Directory of Open Access Journals (Sweden)

    Laurel D Wright

    2015-10-01

    Full Text Available We identified a functional single strand origin of replication (sso in the integrative and conjugative element ICEBs1 of Bacillus subtilis. Integrative and conjugative elements (ICEs, also known as conjugative transposons are DNA elements typically found integrated into a bacterial chromosome where they are transmitted to daughter cells by chromosomal replication and cell division. Under certain conditions, ICEs become activated and excise from the host chromosome and can transfer to neighboring cells via the element-encoded conjugation machinery. Activated ICEBs1 undergoes autonomous rolling circle replication that is needed for the maintenance of the excised element in growing and dividing cells. Rolling circle replication, used by many plasmids and phages, generates single-stranded DNA (ssDNA. In many cases, the presence of an sso enhances the conversion of the ssDNA to double-stranded DNA (dsDNA by enabling priming of synthesis of the second DNA strand. We initially identified sso1 in ICEBs1 based on sequence similarity to the sso of an RCR plasmid. Several functional assays confirmed Sso activity. Genetic analyses indicated that ICEBs1 uses sso1 and at least one other region for second strand DNA synthesis. We found that Sso activity was important for two key aspects of the ICEBs1 lifecycle: 1 maintenance of the plasmid form of ICEBs1 in cells after excision from the chromosome, and 2 stable acquisition of ICEBs1 following transfer to a new host. We identified sequences similar to known plasmid sso's in several other ICEs. Together, our results indicate that many other ICEs contain at least one single strand origin of replication, that these ICEs likely undergo autonomous replication, and that replication contributes to the stability and spread of these elements.

  20. [Integrity].

    Science.gov (United States)

    Gómez Rodríguez, Rafael Ángel

    2014-01-01

    To say that someone possesses integrity is to claim that that person is almost predictable about responses to specific situations, that he or she can prudentially judge and to act correctly. There is a closed interrelationship between integrity and autonomy, and the autonomy rests on the deeper moral claim of all humans to integrity of the person. Integrity has two senses of significance for medical ethic: one sense refers to the integrity of the person in the bodily, psychosocial and intellectual elements; and in the second sense, the integrity is the virtue. Another facet of integrity of the person is la integrity of values we cherish and espouse. The physician must be a person of integrity if the integrity of the patient is to be safeguarded. The autonomy has reduced the violations in the past, but the character and virtues of the physician are the ultimate safeguard of autonomy of patient. A field very important in medicine is the scientific research. It is the character of the investigator that determines the moral quality of research. The problem arises when legitimate self-interests are replaced by selfish, particularly when human subjects are involved. The final safeguard of moral quality of research is the character and conscience of the investigator. Teaching must be relevant in the scientific field, but the most effective way to teach virtue ethics is through the example of the a respected scientist.

  1. Cellular variability of RpoS expression underlies subpopulation activation of an integrative and conjugative element.

    Directory of Open Access Journals (Sweden)

    Ryo Miyazaki

    Full Text Available Conjugative transfer of the integrative and conjugative element ICEclc in the bacterium Pseudomonas knackmussii is the consequence of a bistable decision taken in some 3% of cells in a population during stationary phase. Here we study the possible control exerted by the stationary phase sigma factor RpoS on the bistability decision. The gene for RpoS in P. knackmussii B13 was characterized, and a loss-of-function mutant was produced and complemented. We found that, in absence of RpoS, ICEclc transfer rates and activation of two key ICEclc promoters (P(int and P(inR decrease significantly in cells during stationary phase. Microarray and gene reporter analysis indicated that the most direct effect of RpoS is on P(inR, whereas one of the gene products from the P(inR-controlled operon (InrR transmits activation to P(int and other ICEclc core genes. Addition of a second rpoS copy under control of its native promoter resulted in an increase of the proportion of cells expressing the P(int and P(inR promoters to 18%. Strains in which rpoS was replaced by an rpoS-mcherry fusion showed high mCherry fluorescence of individual cells that had activated P(int and P(inR, whereas a double-copy rpoS-mcherry-containing strain displayed twice as much mCherry fluorescence. This suggested that high RpoS levels are a prerequisite for an individual cell to activate P(inR and thus ICEclc transfer. Double promoter-reporter fusions confirmed that expression of P(inR is dominated by extrinsic noise, such as being the result of cellular variability in RpoS. In contrast, expression from P(int is dominated by intrinsic noise, indicating it is specific to the ICEclc transmission cascade. Our results demonstrate how stochastic noise levels of global transcription factors can be transduced to a precise signaling cascade in a subpopulation of cells leading to ICE activation.

  2. An improved algorithm for the polycrystal viscoplastic self-consistent model and its integration with implicit finite element schemes

    International Nuclear Information System (INIS)

    Galán, J; Verleysen, P; Lebensohn, R A

    2014-01-01

    A new algorithm for the solution of the deformation of a polycrystalline material using a self-consistent scheme, and its integration as part of the finite element software Abaqus/Standard are presented. The method is based on the original VPSC formulation by Lebensohn and Tomé and its integration with Abaqus/Standard by Segurado et al. The new algorithm has been implemented as a set of Fortran 90 modules, to be used either from a standalone program or from Abaqus subroutines. The new implementation yields the same results as VPSC7, but with a significantly better performance, especially when used in multicore computers. (paper)

  3. Enhanced depth-of-field of an integral imaging microscope using a bifocal holographic optical element-micro lens array.

    Science.gov (United States)

    Kwon, Ki-Chul; Lim, Young-Tae; Shin, Chang-Won; Erdenebat, Munkh-Uchral; Hwang, Jae-Moon; Kim, Nam

    2017-08-15

    We propose and implement an integral imaging microscope with extended depth-of-field (DoF) using a bifocal holographic micro lens array (MLA). The properties of the two MLAs are switched via peristrophic multiplexing, where different properties of the MLA are recorded onto the single holographic optical element (HOE). The recorded MLA properties are perpendicular to each other: after the first mode is recorded, the HOE is rotated by 90° clockwise, and the second mode is recorded. The experimental results confirm that the DoF of the integral imaging microscopy system is extended successfully by using the bifocal MLA.

  4. The design and performance evaluation of the ultrasonic random coil identity-integrity element for underwater safeguards seals

    International Nuclear Information System (INIS)

    Allen, V.H.; Backer, S.; Smith, M.T.

    1983-06-01

    Irradiated fuel discharged from CANDU power reactors is stored underwater and, in order to comply with the requirements of International Safe-guards, the fuel is stacked in sealed containers which are examined at intervals by IAEA inspectors. The seals are verified for identity and integrity and this report describes the design of an identity/integrity element for the seals. The element is in the form of a random coil of wire which is interrogated by ultrasonic methods. An evaluation of thirty-six seals is reported. The application of seals to stacks of fuel was simulated in a water-filled bay at CRNL and repetitive verification measurements were made which simulated inspection procedures. The seal identity signatures were compared using cross-correlation methods and the results show that a broken or tampered seal can be identified with a high level of confidence

  5. An Integrated 4-element Slot-Based MIMO and an UWB Sensing Antenna System for CR Platforms

    KAUST Repository

    Hussain, Rifaqat; Sharawi, Mohammad S.; Shamim, Atif

    2017-01-01

    This paper presents a novel integrated antenna system for cognitive radio (CR) applications. The design consists of a compact 4- element reconfigurable annular slot based multiple-input-multiple-output (MIMO) antenna system integrated within an ultra-wide-band (UWB) sensing antenna. All the antenna elements are planar in structure and designed on a single substrate (RO-4350) with dimensions 60×120×1.5 mm3. The frequency reconfigurable slot based MIMO antenna system is tuned over a wide frequency band from 1.77 GHz to 2.51 GHz while the UWB sensing antenna is covering from 0.75~7.65 GHz The proposed antenna system is suitable for CR enabled wireless devices. The envelope correlation coefficient (ECC) did not exceed 0.248 in the entire operating band of the MIMO antenna part. The maximum measured gain of the MIMO antenna is 3.2 dBi with maximum efficiency of 81%.

  6. Standardization of Schwarz-Christoffel transformation for engineering design of semiconductor and hybrid integrated-circuit elements

    Science.gov (United States)

    Yashin, A. A.

    1985-04-01

    A semiconductor or hybrid structure into a calculable two-dimensional region mapped by the Schwarz-Christoffel transformation and a universal algorithm can be constructed on the basis of Maxwell's electro-magnetic-thermal similarity principle for engineering design of integrated-circuit elements. The design procedure involves conformal mapping of the original region into a polygon and then the latter into a rectangle with uniform field distribution, where conductances and capacitances are calculated, using tabulated standard mapping functions. Subsequent synthesis of a device requires inverse conformal mapping. Devices adaptable as integrated-circuit elements are high-resistance film resistors with periodic serration, distributed-resistance film attenuators with high transformation ratio, coplanar microstrip lines, bipolar transistors, directional couplers with distributed coupling to microstrip lines for microwave bulk devices, and quasirregular smooth matching transitions from asymmetric to coplanar microstrip lines.

  7. An Integrated 4-element Slot-Based MIMO and an UWB Sensing Antenna System for CR Platforms

    KAUST Repository

    Hussain, Rifaqat

    2017-12-08

    This paper presents a novel integrated antenna system for cognitive radio (CR) applications. The design consists of a compact 4- element reconfigurable annular slot based multiple-input-multiple-output (MIMO) antenna system integrated within an ultra-wide-band (UWB) sensing antenna. All the antenna elements are planar in structure and designed on a single substrate (RO-4350) with dimensions 60×120×1.5 mm3. The frequency reconfigurable slot based MIMO antenna system is tuned over a wide frequency band from 1.77 GHz to 2.51 GHz while the UWB sensing antenna is covering from 0.75~7.65 GHz The proposed antenna system is suitable for CR enabled wireless devices. The envelope correlation coefficient (ECC) did not exceed 0.248 in the entire operating band of the MIMO antenna part. The maximum measured gain of the MIMO antenna is 3.2 dBi with maximum efficiency of 81%.

  8. Characterization of a new CAMP factor carried by an integrative and conjugative element in Streptococcus agalactiae and spreading in Streptococci.

    Directory of Open Access Journals (Sweden)

    Sarah Chuzeville

    Full Text Available Genetic exchanges between Streptococci occur frequently and contribute to their genome diversification. Most of sequenced streptococcal genomes carry multiple mobile genetic elements including Integrative and Conjugative Elements (ICEs that play a major role in these horizontal gene transfers. In addition to genes involved in their mobility and regulation, ICEs also carry genes that can confer selective advantages to bacteria. Numerous elements have been described in S. agalactiae especially those integrated at the 3' end of a tRNA(Lys encoding gene. In strain 515 of S. agalactiae, an invasive neonate human pathogen, the ICE (called 515_tRNA(Lys is functional and carries different putative virulence genes including one encoding a putative new CAMP factor in addition to the one previously described. This work demonstrated the functionality of this CAMP factor (CAMP factor II in Lactococcus lactis but also in pathogenic strains of veterinary origin. The search for co-hemolytic factors in a collection of field strains revealed their presence in S. uberis, S. dysgalactiae, but also for the first time in S. equisimilis and S. bovis. Sequencing of these genes revealed the prevalence of a species-specific factor in S. uberis strains (Uberis factor and the presence of a CAMP factor II encoding gene in S. bovis and S. equisimilis. Furthermore, most of the CAMP factor II positive strains also carried an element integrated in the tRNA(Lys gene. This work thus describes a CAMP factor that is carried by a mobile genetic element and has spread to different streptococcal species.

  9. Design of time-pulse coded optoelectronic neuronal elements for nonlinear transformation and integration

    Science.gov (United States)

    Krasilenko, Vladimir G.; Nikolsky, Alexander I.; Lazarev, Alexander A.; Lazareva, Maria V.

    2008-03-01

    In the paper the actuality of neurophysiologically motivated neuron arrays with flexibly programmable functions and operations with possibility to select required accuracy and type of nonlinear transformation and learning are shown. We consider neurons design and simulation results of multichannel spatio-time algebraic accumulation - integration of optical signals. Advantages for nonlinear transformation and summation - integration are shown. The offered circuits are simple and can have intellectual properties such as learning and adaptation. The integrator-neuron is based on CMOS current mirrors and comparators. The performance: consumable power - 100...500 μW, signal period- 0.1...1ms, input optical signals power - 0.2...20 μW time delays - less 1μs, the number of optical signals - 2...10, integration time - 10...100 of signal periods, accuracy or integration error - about 1%. Various modifications of the neuron-integrators with improved performance and for different applications are considered in the paper.

  10. Practical steps toward integrating economic, social and institutional elements in fisheries policy and management

    DEFF Research Database (Denmark)

    Stephenson, Robert L.; Benson, Ashleen J.; Brooks, Kate

    2017-01-01

    of explicit social, economic and institutional objectives; a general lack of process (frameworks, governance) for routine integration of all four pillars of sustainability; and a bias towards biological considerations. Practical integration requires a ‘systems’ approach with explicit consideration...... of strategic and operational aspects of management; multidisciplinary or transdisciplinary evaluations; practical objectives for the four pillars of sustainability; appropriate participation; and a governance system that is able to integrate these diverse considerations in management. We challenge all involved...... governance....

  11. Integrated all optical transmodulator circuits with non-linear gain elements and tunable optical fibers

    NARCIS (Netherlands)

    Kuindersma, P.I.; Leijtens, X.J.M.; Zantvoort, van J.H.C.; Waardt, de H.

    2012-01-01

    We characterize integrated InP circuits for high speed ‘all-optical’ signal processing. Single chip circuits act as optical transistors. Transmodulation is performed by non-linear gain sections. Integrated tunable filters give signal equalization in time domain.

  12. Two simple examples for the micro-nano integration of nanowires as electronic device elements

    International Nuclear Information System (INIS)

    Adelung, Rainer

    2011-01-01

    As a part of the conference talk about the mass fabrication and applications of nanostructures, the aim of this paper is to review and compare two approaches for the simple fabrication and integration and of nanostructures into Si-based microchips. The purpose of the integration is the utilization of the different and advanced electronic properties of nanowires. The first method is based on a fracture approach, that integrates nanowires bound to a Si substrate between micro electrodes. These are arrange in a horizontal manner, the second approach allows to integrate free standing nanowires and even 3 dimensional nanowire networks in the chip. As an example for the electronic properties of the nano-micro integrated structures the UV light sensitivity is sown here.

  13. Integrable nonlinear Schrödinger system on a lattice with three structural elements in the unit cell

    Science.gov (United States)

    Vakhnenko, Oleksiy O.

    2018-05-01

    Developing the idea of increasing the number of structural elements in the unit cell of a quasi-one-dimensional lattice as applied to the semi-discrete integrable systems of nonlinear Schrödinger type, we construct the zero-curvature representation for the general integrable nonlinear system on a lattice with three structural elements in the unit cell. The integrability of the obtained general system permits to find explicitly a number of local conservation laws responsible for the main features of system dynamics and in particular for the so-called natural constraints separating the field variables into the basic and the concomitant ones. Thus, considering the reduction to the semi-discrete integrable system of nonlinear Schrödinger type, we revealed the essentially nontrivial impact of concomitant fields on the Poisson structure and on the whole Hamiltonian formulation of system dynamics caused by the nonzero background values of these fields. On the other hand, the zero-curvature representation of a general nonlinear system serves as an indispensable key to the dressing procedure of system integration based upon the Darboux transformation of the auxiliary linear problem and the implicit Bäcklund transformation of field variables. Due to the symmetries inherent to the six-component semi-discrete integrable nonlinear Schrödinger system with attractive-type nonlinearities, the Darboux-Bäcklund dressing scheme is shown to be simplified considerably, giving rise to the appropriately parameterized multi-component soliton solution consisting of six basic and four concomitant components.

  14. ICESag37, a Novel Integrative and Conjugative Element Carrying Antimicrobial Resistance Genes and Potential Virulence Factors in Streptococcus agalactiae.

    Science.gov (United States)

    Zhou, Kaixin; Xie, Lianyan; Han, Lizhong; Guo, Xiaokui; Wang, Yong; Sun, Jingyong

    2017-01-01

    ICE Sag37 , a novel integrative and conjugative element carrying multidrug resistance and potential virulence factors, was characterized in a clinical isolate of Streptococcus agalactiae . Two clinical strains of S. agalactiae , Sag37 and Sag158, were isolated from blood samples of new-borns with bacteremia. Sag37 was highly resistant to erythromycin and tetracycline, and susceptible to levofloxacin and penicillin, while Sag158 was resistant to tetracycline and levofloxacin, and susceptible to erythromycin. Transfer experiments were performed and selection was carried out with suitable antibiotic concentrations. Through mating experiments, the erythromycin resistance gene was found to be transferable from Sag37 to Sag158. Sma I-PFGE revealed a new Sma I fragment, confirming the transfer of the fragment containing the erythromycin resistance gene. Whole genome sequencing and sequence analysis revealed a mobile element, ICE Sag37 , which was characterized using several molecular methods and in silico analyses. ICE Sag37 was excised to generate a covalent circular intermediate, which was transferable to S. agalactiae . Inverse PCR was performed to detect the circular form. A serine family integrase mediated its chromosomal integration into rumA , which is a known hotspot for the integration of streptococcal ICEs. The integration site was confirmed using PCR. ICE Sag37 carried genes for resistance to multiple antibiotics, including erythromycin [ erm(B) ], tetracycline [ tet(O) ], and aminoglycosides [ aadE, aphA , and ant(6) ]. Potential virulence factors, including a two-component signal transduction system ( nisK/nisR ), were also observed in ICE Sag37 . S1-PFGE analysis ruled out the existence of plasmids. ICE Sag37 is the first ICE Sa2603 family-like element identified in S. agalactiae carrying both resistance and potential virulence determinants. It might act as a vehicle for the dissemination of multidrug resistance and pathogenicity among S. agalactiae .

  15. Thermomechanical stability and integrability of an embedded ceramic antenna with an integrated sensor element for wireless reading in harsh environments

    Science.gov (United States)

    Sturesson, P.; Khaji, Z.; Knaust, S.; Sundqvist, J.; Klintberg, L.; Thornell, G.

    2013-12-01

    This paper reports on the design, manufacturing and evaluation of a small, wirelessly powered and read resonating antenna circuit with an integrated pressure sensor. The work aims at developing miniature devices suitable for harsh environments, where high temperature prevents the use of conventional, silicon-based microdevices. Here, the device is made of alumina with platinum as conducting material. Ceramic green tapes were structured using high-precision milling, metallized using screen printing, and subsequently laminated to form stacks before they were sintered. The device's frequency shift as a function of temperature was studied up to 900°C. The contributions to the shift both from the thermomechanical deformation of the device at large, and from the integrated and, so far, self-pressurized sensor were sorted out. A total frequency shift of 3200 ppm was observed for the pressure sensor for heating over the whole range. Negligible levels of thermally induced radius of curvature were observed. With three-point bending, a frequency shift of 180 ppm was possible to induce with a curvature of radius of 220 m at a 10 N load. The results indicate that a robust pressure sensor node, which can register pressure changes of a few bars at 900°C and wirelessly transmit the signal, is viable.

  16. Thermomechanical stability and integrability of an embedded ceramic antenna with an integrated sensor element for wireless reading in harsh environments

    International Nuclear Information System (INIS)

    Sturesson, P; Sundqvist, J; Thornell, G; Khaji, Z; Knaust, S; Klintberg, L

    2013-01-01

    This paper reports on the design, manufacturing and evaluation of a small, wirelessly powered and read resonating antenna circuit with an integrated pressure sensor. The work aims at developing miniature devices suitable for harsh environments, where high temperature prevents the use of conventional, silicon-based microdevices. Here, the device is made of alumina with platinum as conducting material. Ceramic green tapes were structured using high-precision milling, metallized using screen printing, and subsequently laminated to form stacks before they were sintered. The device's frequency shift as a function of temperature was studied up to 900°C. The contributions to the shift both from the thermomechanical deformation of the device at large, and from the integrated and, so far, self-pressurized sensor were sorted out. A total frequency shift of 3200 ppm was observed for the pressure sensor for heating over the whole range. Negligible levels of thermally induced radius of curvature were observed. With three-point bending, a frequency shift of 180 ppm was possible to induce with a curvature of radius of 220 m at a 10 N load. The results indicate that a robust pressure sensor node, which can register pressure changes of a few bars at 900°C and wirelessly transmit the signal, is viable

  17. Nonlinear finite element modeling of vibration control of plane rod-type structural members with integrated piezoelectric patches

    Science.gov (United States)

    Chróścielewski, Jacek; Schmidt, Rüdiger; Eremeyev, Victor A.

    2018-05-01

    This paper addresses modeling and finite element analysis of the transient large-amplitude vibration response of thin rod-type structures (e.g., plane curved beams, arches, ring shells) and its control by integrated piezoelectric layers. A geometrically nonlinear finite beam element for the analysis of piezolaminated structures is developed that is based on the Bernoulli hypothesis and the assumptions of small strains and finite rotations of the normal. The finite element model can be applied to static, stability, and transient analysis of smart structures consisting of a master structure and integrated piezoelectric actuator layers or patches attached to the upper and lower surfaces. Two problems are studied extensively: (i) FE analyses of a clamped semicircular ring shell that has been used as a benchmark problem for linear vibration control in several recent papers are critically reviewed and extended to account for the effects of structural nonlinearity and (ii) a smart circular arch subjected to a hydrostatic pressure load is investigated statically and dynamically in order to study the shift of bifurcation and limit points, eigenfrequencies, and eigenvectors, as well as vibration control for loading conditions which may lead to dynamic loss of stability.

  18. Bending analysis of embedded nanoplates based on the integral formulation of Eringen's nonlocal theory using the finite element method

    Science.gov (United States)

    Ansari, R.; Torabi, J.; Norouzzadeh, A.

    2018-04-01

    Due to the capability of Eringen's nonlocal elasticity theory to capture the small length scale effect, it is widely used to study the mechanical behaviors of nanostructures. Previous studies have indicated that in some cases, the differential form of this theory cannot correctly predict the behavior of structure, and the integral form should be employed to avoid obtaining inconsistent results. The present study deals with the bending analysis of nanoplates resting on elastic foundation based on the integral formulation of Eringen's nonlocal theory. Since the formulation is presented in a general form, arbitrary kernel functions can be used. The first order shear deformation plate theory is considered to model the nanoplates, and the governing equations for both integral and differential forms are presented. Finally, the finite element method is applied to solve the problem. Selected results are given to investigate the effects of elastic foundation and to compare the predictions of integral nonlocal model with those of its differential nonlocal and local counterparts. It is found that by the use of proposed integral formulation of Eringen's nonlocal model, the paradox observed for the cantilever nanoplate is resolved.

  19. Finite element modelling of shot peening process: Prediction of the compressive residual stresses, the plastic deformations and the surface integrity

    International Nuclear Information System (INIS)

    Frija, M.; Hassine, T.; Fathallah, R.; Bouraoui, C.; Dogui, A.

    2006-01-01

    This paper presents a numerical simulation of the shot peening process using finite element method. The majority of the controlling parameters of the process have been taken into account. The shot peening loading has been characterised by using energy equivalence between the dynamic impact and a static indentation of a peening shot in the treated surface. The behaviour of the subjected material is supposed to be elastic plastic with damage. An integrated law of the damage proposed by Lemaitre and Chaboche has been used. The proposed model leads to obtain the residual stress, the plastic deformation profiles and the surface damage. An application on a shot peened Ni-based super alloy Waspaloy has been carried out. The comparison of the residual stresses, obtained by X-ray diffraction method and by finite element calculation, shows a good correlation. The in-depth profile of the plastic deformations and the superficial damage values are in good agreement with the experimental observations

  20. Gene disruptions using P transposable elements: an integral component of the Drosophila genome project.

    OpenAIRE

    Spradling, A C; Stern, D M; Kiss, I; Roote, J; Laverty, T; Rubin, G M

    1995-01-01

    Biologists require genetic as well as molecular tools to decipher genomic information and ultimately to understand gene function. The Berkeley Drosophila Genome Project is addressing these needs with a massive gene disruption project that uses individual, genetically engineered P transposable elements to target open reading frames throughout the Drosophila genome. DNA flanking the insertions is sequenced, thereby placing an extensive series of genetic markers on the physical genomic map and a...

  1. The accuracy of the Gaussian-and-finite-element-Coulomb (GFC) method for the calculation of Coulomb integrals.

    Science.gov (United States)

    Przybytek, Michal; Helgaker, Trygve

    2013-08-07

    We analyze the accuracy of the Coulomb energy calculated using the Gaussian-and-finite-element-Coulomb (GFC) method. In this approach, the electrostatic potential associated with the molecular electronic density is obtained by solving the Poisson equation and then used to calculate matrix elements of the Coulomb operator. The molecular electrostatic potential is expanded in a mixed Gaussian-finite-element (GF) basis set consisting of Gaussian functions of s symmetry centered on the nuclei (with exponents obtained from a full optimization of the atomic potentials generated by the atomic densities from symmetry-averaged restricted open-shell Hartree-Fock theory) and shape functions defined on uniform finite elements. The quality of the GF basis is controlled by means of a small set of parameters; for a given width of the finite elements d, the highest accuracy is achieved at smallest computational cost when tricubic (n = 3) elements are used in combination with two (γ(H) = 2) and eight (γ(1st) = 8) Gaussians on hydrogen and first-row atoms, respectively, with exponents greater than a given threshold (αmin (G)=0.5). The error in the calculated Coulomb energy divided by the number of atoms in the system depends on the system type but is independent of the system size or the orbital basis set, vanishing approximately like d(4) with decreasing d. If the boundary conditions for the Poisson equation are calculated in an approximate way, the GFC method may lose its variational character when the finite elements are too small; with larger elements, it is less sensitive to inaccuracies in the boundary values. As it is possible to obtain accurate boundary conditions in linear time, the overall scaling of the GFC method for large systems is governed by another computational step-namely, the generation of the three-center overlap integrals with three Gaussian orbitals. The most unfavorable (nearly quadratic) scaling is observed for compact, truly three-dimensional systems

  2. Miniaturized flow cytometer with 3D hydrodynamic particle focusing and integrated optical elements applying silicon photodiodes

    NARCIS (Netherlands)

    Rosenauer, M.; Buchegger, W.; Finoulst, I.; Verhaert, P.D.E.M.; Vellekoop, M.

    2010-01-01

    In this study, the design, realization and measurement results of a novel optofluidic system capable of performing absorbance-based flow cytometric analysis is presented. This miniaturized laboratory platform, fabricated using SU-8 on a silicon substrate, comprises integrated polymer-based

  3. Integrating Literature with Craft in a Learning Process with Creative Elements

    Science.gov (United States)

    Aerila, Juli-Anna; Rönkkö, Marja-Leena

    2015-01-01

    Art-related learning should be the central way of doing and playing in preschool, because the high quality of art-related education has a positive effect on children's well-being, identity development, and creative thinking. In our study we tested an integrated learning process where reading literature and telling stories is combined with the…

  4. Academic Use of Social Media Technologies as an Integral Element of Informatics Program Delivery in Malaysia

    Science.gov (United States)

    Lim, Jane See Yin; Harper, Barry; Chicharo, Joe F.

    2014-01-01

    Higher education institutions are currently examining how the current emerging technologies and social media applications can be integrated with the appropriate teaching pedagogies adopted by higher education institutions to provide students with learning experiences that take advantage of these new affordances. Due to the continuous and pervasive…

  5. Geomechanical Simulations of CO2 Storage Integrity using the Livermore Distinct Element Method

    Energy Technology Data Exchange (ETDEWEB)

    Morris, J P; Johnson, S M; Friedmann, S J

    2008-07-11

    Large-scale carbon capture and sequestration (CCS) projects involving annual injections of millions of tons of CO{sub 2} are a key infrastructural element needed to substantially reduce greenhouse gas emissions. The large rate and volume of injection will induce pressure and stress gradients within the formation that could activate existing fractures and faults, or drive new fractures through the caprock. We will present results of an ongoing investigation to identify conditions that will activate existing fractures/faults or make new fractures within the caprock using the Livermore Distinct Element Code (LDEC). LDEC is a multiphysics code, developed at LLNL, capable of simulating dynamic fracture of rock masses under a range of conditions. As part of a recent project, LDEC has been extended to consider fault activation and dynamic fracture of rock masses due to pressurization of the pore-space. We will present several demonstrations of LDEC functionality and applications of LDEC to CO{sub 2} injection scenarios including injection into an extensively fractured rockmass. These examples highlight the advantages of explicitly including the geomechanical response of each interface within the rockmass. We present results from our investigations of Teapot Dome using LDEC to study the potential for fault activation during injection. Using this approach, we built finite element models of the rock masses surrounding bounding faults and explicitly simulated the compression and shear on the fault interface. A CO{sub 2} injection source was introduced and the area of fault activation was predicted as a function of injection rate. This work presents an approach where the interactions of all locations on the fault are considered in response to specific injection scenarios. For example, with LDEC, as regions of the fault fail, the shear load is taken up elsewhere on the fault. The results of this study are consistent with previous studies of Teapot Dome and indicate

  6. Geomechanical Simulations of Caprock Integrity Using the Livermore Distinict Element Method

    Energy Technology Data Exchange (ETDEWEB)

    Morris, J; Johnson, S; Friedmann, S J

    2008-04-17

    Large-scale carbon capture and sequestration (CCS) projects involving annual injections of millions of tons of CO2 are a key infrastructural element needed to substantially reduce greenhouse gas emissions. The large rate and volume of injection will induce pressure and stress gradients within the formation that could activate existing fractures and faults, or drive new fractures through the caprock. We will present results of an ongoing investigation to identify conditions that will activate existing fractures/faults or make new fractures within the caprock using the Livermore Distinct Element Code (LDEC). LDEC is a multiphysics code, developed at LLNL, capable of simulating dynamic fracture of rock masses under a range of conditions. As part of a recent project, LDEC has been extended to consider fault activation and dynamic fracture of rock masses due to pressurization of the pore-space. We will present several demonstrations of LDEC functionality and an application of LDEC to a CO2 injection scenario. We present results from our investigations of Teapot Dome using LDEC to study the potential for fault activation during injection. Using this approach, we built finite element models of the rock masses surrounding bounding faults and explicitly simulated the compression and shear on the fault interface. A CO2 injection source was introduced and the area of fault activation was predicted as a function of injection rate. This work presents an approach where the interactions of all locations on the fault are considered in response to specific injection scenarios. For example, with LDEC, as regions of the fault fail, the shear load is taken up elsewhere on the fault. The results of this study are consistent with previous studies of Teapot Dome and indicate significantly elevated pore pressures are required to activate the bounding faults, given the assumed in situ stress state on the faults.

  7. The Role of Heterologous Chloroplast Sequence Elements in Transgene Integration and Expression1[W][OA

    Science.gov (United States)

    Ruhlman, Tracey; Verma, Dheeraj; Samson, Nalapalli; Daniell, Henry

    2010-01-01

    Heterologous regulatory elements and flanking sequences have been used in chloroplast transformation of several crop species, but their roles and mechanisms have not yet been investigated. Nucleotide sequence identity in the photosystem II protein D1 (psbA) upstream region is 59% across all taxa; similar variation was consistent across all genes and taxa examined. Secondary structure and predicted Gibbs free energy values of the psbA 5′ untranslated region (UTR) among different families reflected this variation. Therefore, chloroplast transformation vectors were made for tobacco (Nicotiana tabacum) and lettuce (Lactuca sativa), with endogenous (Nt-Nt, Ls-Ls) or heterologous (Nt-Ls, Ls-Nt) psbA promoter, 5′ UTR and 3′ UTR, regulating expression of the anthrax protective antigen (PA) or human proinsulin (Pins) fused with the cholera toxin B-subunit (CTB). Unique lettuce flanking sequences were completely eliminated during homologous recombination in the transplastomic tobacco genomes but not unique tobacco sequences. Nt-Ls or Ls-Nt transplastomic lines showed reduction of 80% PA and 97% CTB-Pins expression when compared with endogenous psbA regulatory elements, which accumulated up to 29.6% total soluble protein PA and 72.0% total leaf protein CTB-Pins, 2-fold higher than Rubisco. Transgene transcripts were reduced by 84% in Ls-Nt-CTB-Pins and by 72% in Nt-Ls-PA lines. Transcripts containing endogenous 5′ UTR were stabilized in nonpolysomal fractions. Stromal RNA-binding proteins were preferentially associated with endogenous psbA 5′ UTR. A rapid and reproducible regeneration system was developed for lettuce commercial cultivars by optimizing plant growth regulators. These findings underscore the need for sequencing complete crop chloroplast genomes, utilization of endogenous regulatory elements and flanking sequences, as well as optimization of plant growth regulators for efficient chloroplast transformation. PMID:20130101

  8. The role of heterologous chloroplast sequence elements in transgene integration and expression.

    Science.gov (United States)

    Ruhlman, Tracey; Verma, Dheeraj; Samson, Nalapalli; Daniell, Henry

    2010-04-01

    Heterologous regulatory elements and flanking sequences have been used in chloroplast transformation of several crop species, but their roles and mechanisms have not yet been investigated. Nucleotide sequence identity in the photosystem II protein D1 (psbA) upstream region is 59% across all taxa; similar variation was consistent across all genes and taxa examined. Secondary structure and predicted Gibbs free energy values of the psbA 5' untranslated region (UTR) among different families reflected this variation. Therefore, chloroplast transformation vectors were made for tobacco (Nicotiana tabacum) and lettuce (Lactuca sativa), with endogenous (Nt-Nt, Ls-Ls) or heterologous (Nt-Ls, Ls-Nt) psbA promoter, 5' UTR and 3' UTR, regulating expression of the anthrax protective antigen (PA) or human proinsulin (Pins) fused with the cholera toxin B-subunit (CTB). Unique lettuce flanking sequences were completely eliminated during homologous recombination in the transplastomic tobacco genomes but not unique tobacco sequences. Nt-Ls or Ls-Nt transplastomic lines showed reduction of 80% PA and 97% CTB-Pins expression when compared with endogenous psbA regulatory elements, which accumulated up to 29.6% total soluble protein PA and 72.0% total leaf protein CTB-Pins, 2-fold higher than Rubisco. Transgene transcripts were reduced by 84% in Ls-Nt-CTB-Pins and by 72% in Nt-Ls-PA lines. Transcripts containing endogenous 5' UTR were stabilized in nonpolysomal fractions. Stromal RNA-binding proteins were preferentially associated with endogenous psbA 5' UTR. A rapid and reproducible regeneration system was developed for lettuce commercial cultivars by optimizing plant growth regulators. These findings underscore the need for sequencing complete crop chloroplast genomes, utilization of endogenous regulatory elements and flanking sequences, as well as optimization of plant growth regulators for efficient chloroplast transformation.

  9. Differential regulation of two closely related integrative and conjugative elements from Streptococcus thermophilus

    Directory of Open Access Journals (Sweden)

    Carraro Nicolas

    2011-10-01

    Full Text Available Abstract Background Two closely related ICEs, ICESt1 and ICESt3, have been identified in the lactic acid bacterium Streptococcus thermophilus. While their conjugation and recombination modules are almost identical (95% nucleotide identity and their regulation modules related, previous work has demonstrated that transconjugants carrying ICESt3 were generated at rate exceeding by a 1000 factor that of ICESt1. Results The functional regulation of ICESt1 and ICESt3 transcription, excision and replication were investigated under different conditions (exponential growth or stationary phase, DNA damage by exposition to mitomycin C. Analysis revealed an identical transcriptional organization of their recombination and conjugation modules (long unique transcript whereas the transcriptional organization of their regulation modules were found to be different (two operons in ICESt1 but only one in ICESt3 and to depend on the conditions (promoter specific of stationary phase in ICESt3. For both elements, stationary phase and DNA damage lead to the rise of transcript levels of the conjugation-recombination and regulation modules. Whatever the growth culture conditions, excision of ICESt1 was found to be lower than that of ICESt3, which is consistent with weaker transfer frequencies. Furthermore, for both elements, excision increases in stationary phase (8.9-fold for ICESt1 and 1.31-fold for ICESt3 and is strongly enhanced by DNA damage (38-fold for ICESt1 and 18-fold for ICESt3. Although ICEs are generally not described as replicative elements, the copy number of ICESt3 exhibited a sharp increase (9.6-fold after mitomycin C exposure of its harboring strain CNRZ385. This result was not observed when ICESt3 was introduced in a strain deriving ICESt1 host strain CNRZ368, deleted for this element. This finding suggests an impact of the host cell on ICE behavior. Conclusions All together, these results suggest a novel mechanism of regulation shared by ICESt1

  10. Microchip Flow Cytometer with Integrated Polymer Optical Elements for Measurement of Scattered Light

    DEFF Research Database (Denmark)

    Wang, Zhenyu; El-Ali, Jamil; Perch-Nielsen, Ivan Ryberg

    2004-01-01

    channels to form a complete microchip flow cytometer. All the optical elements, the microfluidic system, and the fiber-to-waveguide couplers were defined in one layer of polymer (SU-8, negative photoresist) by standard photolithography. With only one single mask procedure, all the fabrication and packaging...... processes can be finished in one day. Polystyrene beads were measured in the microchip flow cytometer, and three signals (forward scattering, large angle scattering and extinction) were measured simultaneously for each bead. The average intensities of the forward Scattered light and the incident light...

  11. Simulating Dynamic Vehicle Maneuvers Using Finite Elements For Use In Design Of Integrated Composite Structure

    OpenAIRE

    Angelini, Nicholas Alexander

    2014-01-01

    Formula SAE (FSAE) chassis systems are increasing being manufactured with integrated composite structures in an effort to increase the performance of the system while decreasing weight. The increased use of composite structures requires more details of the loading conditions and evaluation metrics than the mild steel structures they are replacing. The prototypical FSAE steel space frame chassis designs are heavily structured around the mandated safety rules that doubled as mostly satisfactory...

  12. Finite Element Analysis of Single Cell Stiffness Measurements Using PZT-Integrated Buckling Nanoneedles.

    Science.gov (United States)

    Rad, Maryam Alsadat; Tijjani, Auwal Shehu; Ahmad, Mohd Ridzuan; Auwal, Shehu Muhammad

    2016-12-23

    This paper proposes a new technique for real-time single cell stiffness measurement using lead zirconate titanate (PZT)-integrated buckling nanoneedles. The PZT and the buckling part of the nanoneedle have been modelled and validated using the ABAQUS software. The two parts are integrated together to function as a single unit. After calibration, the stiffness, Young's modulus, Poisson's ratio and sensitivity of the PZT-integrated buckling nanoneedle have been determined to be 0.7100 N·m -1 , 123.4700 GPa, 0.3000 and 0.0693 V·m·N -1 , respectively. Three Saccharomyces cerevisiae cells have been modelled and validated based on compression tests. The average global stiffness and Young's modulus of the cells are determined to be 10.8867 ± 0.0094 N·m -1 and 110.7033 ± 0.0081 MPa, respectively. The nanoneedle and the cell have been assembled to measure the local stiffness of the single Saccharomyces cerevisiae cells The local stiffness, Young's modulus and PZT output voltage of the three different size Saccharomyces cerevisiae have been determined at different environmental conditions. We investigated that, at low temperature the stiffness value is low to adapt to the change in the environmental condition. As a result, Saccharomyces cerevisiae becomes vulnerable to viral and bacterial attacks. Therefore, the proposed technique will serve as a quick and accurate process to diagnose diseases at early stage in a cell for effective treatment.

  13. Engineering C-integral estimates for generalised creep behaviour and finite element validation

    International Nuclear Information System (INIS)

    Kim, Yun-Jae; Kim, Jin-Su; Huh, Nam-Su; Kim, Young-Jin

    2002-01-01

    This paper proposes an engineering method to estimate the creep C-integral for realistic creep laws to assess defective components operating at elevated temperatures. The proposed estimation method is mainly for the steady-state C * -integral, but a suggestion is also given for estimating the transient C(t)-integral. The reference stress approach is the basis of the proposed equation, but an enhancement in terms of accuracy is made through the definition of the reference stress. The proposed estimation equations are compared with extensive elastic-creep FE results employing various creep-deformation constitutive laws for six different geometries, including two-dimensional, axi-symmetric and three-dimensional geometries. Overall good agreement between the proposed method and the FE results provides confidence in the use of the proposed method for defect assessment of components at elevated temperatures. Moreover, it is shown that for surface cracks the proposed method can be used to estimate C * at any location along the crack front

  14. Formation of elements of integrated acousto-optic cell based on LiNbO3 films by methods of nanotechnology

    International Nuclear Information System (INIS)

    Ageev, O A; Zamburg, E G; Kolomiytsev, A S; Suchkov, D O; Shipulin, I A; Shumov, A V

    2015-01-01

    In the experiments we defined modes, and developed the technology of formation of elements of input-output laser emission and microlens of integrated acousto-optic cell by Pulsed Laser Deposition and Focused Ion Beams by using nanotechnology cluster complex, allowing controlled creation of elements in a single process cycle. (paper)

  15. Determination of integral K-shell Compton scattering cross-sections in elements 41>=Z>=51 for 1250 keV photons

    Energy Technology Data Exchange (ETDEWEB)

    Verma, S L; Allawadhi, K L; Sood, B S [Punjabi Univ., Patiala (India). Dept. of Physics

    1978-04-01

    Integral K-shell Compton scattering cross-sections in elements Nb, Mo, Ag, Cd, In, Sn and Sb have been determined for 1250 keV photons. The results when compared with theory suggest that K-shell electrons in the elements under investigation behave as free electrons.

  16. The extended regulatory networks of SXT/R391 integrative and conjugative elements and IncA/C conjugative plasmids.

    Science.gov (United States)

    Poulin-Laprade, Dominic; Carraro, Nicolas; Burrus, Vincent

    2015-01-01

    Nowadays, healthcare systems are challenged by a major worldwide drug resistance crisis caused by the massive and rapid dissemination of antibiotic resistance genes and associated emergence of multidrug resistant pathogenic bacteria, in both clinical and environmental settings. Conjugation is the main driving force of gene transfer among microorganisms. This mechanism of horizontal gene transfer mediates the translocation of large DNA fragments between two bacterial cells in direct contact. Integrative and conjugative elements (ICEs) of the SXT/R391 family (SRIs) and IncA/C conjugative plasmids (ACPs) are responsible for the dissemination of a broad spectrum of antibiotic resistance genes among diverse species of Enterobacteriaceae and Vibrionaceae. The biology, diversity, prevalence and distribution of these two families of conjugative elements have been the subject of extensive studies for the past 15 years. Recently, the transcriptional regulators that govern their dissemination through the expression of ICE- or plasmid-encoded transfer genes have been described. Unrelated repressors control the activation of conjugation by preventing the expression of two related master activator complexes in both types of elements, i.e., SetCD in SXT/R391 ICEs and AcaCD in IncA/C plasmids. Finally, in addition to activating ICE- or plasmid-borne genes, these master activators have been shown to specifically activate phylogenetically unrelated mobilizable genomic islands (MGIs) that also disseminate antibiotic resistance genes and other adaptive traits among a plethora of pathogens such as Vibrio cholerae and Salmonella enterica.

  17. Definition, technology readiness, and development cost of the orbit transfer vehicle engine integrated control and health monitoring system elements

    Science.gov (United States)

    Cannon, I.; Balcer, S.; Cochran, M.; Klop, J.; Peterson, S.

    1991-01-01

    An Integrated Control and Health Monitoring (ICHM) system was conceived for use on a 20 Klb thrust baseline Orbit Transfer Vehicle (OTV) engine. Considered for space used, the ICHM was defined for reusability requirements for an OTV engine service free life of 20 missions, with 100 starts and a total engine operational time of 4 hours. Functions were derived by flowing down requirements from NASA guidelines, previous OTV engine or ICHM documents, and related contracts. The elements of an ICHM were identified and listed, and these elements were described in sufficient detail to allow estimation of their technology readiness levels. These elements were assessed in terms of technology readiness level, and supporting rationale for these assessments presented. The remaining cost for development of a minimal ICHM system to technology readiness level 6 was estimated. The estimates are within an accuracy range of minus/plus 20 percent. The cost estimates cover what is needed to prepare an ICHM system for use on a focussed testbed for an expander cycle engine, excluding support to the actual test firings.

  18. The extended regulatory networks of SXT/R391 integrative and conjugative elements and IncA/C conjugative plasmids.

    Directory of Open Access Journals (Sweden)

    Dominic ePoulin-Laprade

    2015-08-01

    Full Text Available Nowadays, healthcare systems are challenged by a major worldwide drug resistance crisis caused by the massive and rapid dissemination of antibiotic resistance genes and associated emergence of multidrug resistant pathogenic bacteria, in both clinical and environmental settings. Conjugation is the main driving force of gene transfer among microorganisms. This mechanism of horizontal gene transfer mediates the translocation of large DNA fragments between two bacterial cells in direct contact. Integrative and conjugative elements (ICEs of the SXT/R391 family (SRIs and IncA/C conjugative plasmids (ACPs are responsible for the dissemination of a broad spectrum of antibiotic resistance genes among diverse species of Enterobacteriaceae and Vibrionaceae. The biology, diversity, prevalence and distribution of these two families of conjugative elements have been the subject of extensive studies for the past 15 years. Recently, the transcriptional regulators that govern their dissemination through the expression of ICE- or plasmid-encoded transfer genes have been described. Unrelated repressors control the activation of conjugation by preventing the expression of two related master activator complexes in both types of elements, i.e. SetCD in SXT/R391 ICEs and AcaCD in IncA/C plasmids. Finally, in addition to activating ICE- or plasmid-borne genes, these master activators have been shown to specifically activate phylogenetically unrelated mobilizable genomic islands (MGIs that also disseminate antibiotic resistance genes and other adaptive traits among a plethora of pathogens such as Vibrio cholerae and Salmonella enterica.

  19. Integration of finite element analysis and design of experiments to analyse the geometrical factors in bi-layered tube hydroforming

    International Nuclear Information System (INIS)

    Alaswad, A.; Olabi, A.G.; Benyounis, K.Y.

    2011-01-01

    Tube hydroforming (THF) is a type of unconventional metal forming process in which high fluid pressure and axial feed are used to deform a tube blank in the desired shape. Bi-layered tube hydroforming is suitable to produce bi-layered joints to be used in special applications such as aerospace, oil production and nuclear power plants. In this work, a finite element study along with response surface methodology (RSM) for design of experiment (DOE) has been used to construct models for three responses namely: bulge height, thickness reduction, and wrinkle height as a function of geometrical factors for X shape bi-layered tube hydroforming. A finite element model was built and experimentally validated. The models developed using finite element analysis (FEA) and RSM was found to be educated. The factors effect and their interactions on the three responses were determined and discussed. Such integration was proved to be a successful technique that can be used to predict the geometry of the hydroformed part.

  20. Finite Element Analysis of Single Cell Stiffness Measurements Using PZT-Integrated Buckling Nanoneedles

    Directory of Open Access Journals (Sweden)

    Maryam Alsadat Rad

    2016-12-01

    Full Text Available This paper proposes a new technique for real-time single cell stiffness measurement using lead zirconate titanate (PZT-integrated buckling nanoneedles. The PZT and the buckling part of the nanoneedle have been modelled and validated using the ABAQUS software. The two parts are integrated together to function as a single unit. After calibration, the stiffness, Young’s modulus, Poisson’s ratio and sensitivity of the PZT-integrated buckling nanoneedle have been determined to be 0.7100 N·m−1, 123.4700 GPa, 0.3000 and 0.0693 V·m·N−1, respectively. Three Saccharomyces cerevisiae cells have been modelled and validated based on compression tests. The average global stiffness and Young’s modulus of the cells are determined to be 10.8867 ± 0.0094 N·m−1 and 110.7033 ± 0.0081 MPa, respectively. The nanoneedle and the cell have been assembled to measure the local stiffness of the single Saccharomyces cerevisiae cells The local stiffness, Young’s modulus and PZT output voltage of the three different size Saccharomyces cerevisiae have been determined at different environmental conditions. We investigated that, at low temperature the stiffness value is low to adapt to the change in the environmental condition. As a result, Saccharomyces cerevisiae becomes vulnerable to viral and bacterial attacks. Therefore, the proposed technique will serve as a quick and accurate process to diagnose diseases at early stage in a cell for effective treatment.

  1. Natural gas as an integrating element for Latin America - An opportunity for Venezuela?

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez Cruz, Diego

    2010-09-15

    Summary This paper offers an analysis of the natural gas situation in Latin America, from Mexico to Argentina, including countries of the Caribbean; analyzes the attitude of potential buyers of this energy source and the possibilities of each country receiving natural gas from Venezuela based on its reserves and production, highlighting the most outstanding projects being undertaken in some of those countries; makes recommendations in the area of energy, with emphasis on natural gas; and, lastly, presents an epilog describing Venezuela's role in an integration process in Latin America.

  2. Integration of a finite element generator model into a simulated HVDC connected system

    Energy Technology Data Exchange (ETDEWEB)

    Preston, T W; Sturgess, J P [GEC Alsthom Engineering Research Center, Stafford (United Kingdom)

    1994-12-31

    Within most system analysis programs generators and motors are represented by an equivalent circuit model either a 2-axis model for both stators and rotor or a three-phase model of the stator and a two-axis model of the rotor. This may be adequate under certain operating conditions such as steady-state or some symmetrical faults but for inverter-fed motors or generators feeding into a rectified load a more rigorous model of the machine is required. This paper describes the theory and development of such a model, its integration with the power electronics and application to 6-pulse and 12-pulse converters, the latter being appropriate in systems similar to HVDC unit connection. (author) 5 refs., 16 figs.

  3. SINGLE-SHELL TANKS LEAK INTEGRITY ELEMENTS/SX FARM LEAK CAUSES AND LOCATIONS - 12127

    Energy Technology Data Exchange (ETDEWEB)

    VENETZ TJ; WASHENFELDER D; JOHNSON J; GIRARDOT C

    2012-01-25

    Washington River Protection Solutions, LLC (WRPS) developed an enhanced single-shell tank (SST) integrity project in 2009. An expert panel on SST integrity was created to provide recommendations supporting the development of the project. One primary recommendation was to expand the leak assessment reports (substitute report or LD-1) to include leak causes and locations. The recommendation has been included in the M-045-9IF Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement) as one of four targets relating to SST leak integrity. The 241-SX Farm (SX Farm) tanks with leak losses were addressed on an individual tank basis as part of LD-1. Currently, 8 out of 23 SSTs that have been reported to having a liner leak are located in SX Farm. This percentage was the highest compared to other tank farms which is why SX Farm was analyzed first. The SX Farm is comprised of fifteen SSTs built 1953-1954. The tanks are arranged in rows of three tanks each, forming a cascade. Each of the SX Farm tanks has a nominal I-million-gal storage capacity. Of the fifteen tanks in SX Farm, an assessment reported leak losses for the following tanks: 241-SX-107, 241-SX-108, 241-SX-109, 241-SX-111, 241-SX-112, 241-SX-113, 241-SX-114 and 241-SX-115. The method used to identify leak location consisted of reviewing in-tank and ex-tank leak detection information. This provided the basic data identifying where and when the first leaks were detected. In-tank leak detection consisted of liquid level measurement that can be augmented with photographs which can provide an indication of the vertical leak location on the sidewall. Ex-tank leak detection for the leaking tanks consisted of soil radiation data from laterals and drywells near the tank. The in-tank and ex-tank leak detection can provide an indication of the possible leak location radially around and under the tank. Potential leak causes were determined using in-tank and ex-tank information that is not directly related to

  4. Single-Shell Tanks Leak Integrity Elements/ SX Farm Leak Causes and Locations - 12127

    Energy Technology Data Exchange (ETDEWEB)

    Girardot, Crystal [URS- Safety Management Solutions, Richland, Washington 99352 (United States); Harlow, Don [ELR Consulting Richland, Washington 99352 (United States); Venetz, Theodore; Washenfelder, Dennis [Washington River Protection Solutions, LLC Richland, Washington 99352 (United States); Johnson, Jeremy [U.S. Department of Energy, Office of River Protection Richland, Washington 99352 (United States)

    2012-07-01

    Washington River Protection Solutions, LLC (WRPS) developed an enhanced single-shell tank (SST) integrity project in 2009. An expert panel on SST integrity was created to provide recommendations supporting the development of the project. One primary recommendation was to expand the leak assessment reports (substitute report or LD-1) to include leak causes and locations. The recommendation has been included in the M-045-91F Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement) as one of four targets relating to SST leak integrity. The 241-SX Farm (SX Farm) tanks with leak losses were addressed on an individual tank basis as part of LD-1. Currently, 8 out of 23 SSTs that have been reported to having a liner leak are located in SX Farm. This percentage was the highest compared to other tank farms which is why SX Farm was analyzed first. The SX Farm is comprised of fifteen SSTs built 1953-1954. The tanks are arranged in rows of three tanks each, forming a cascade. Each of the SX Farm tanks has a nominal 1-million-gal storage capacity. Of the fifteen tanks in SX Farm, an assessment reported leak losses for the following tanks: 241-SX-107, 241-SX-108, 241-SX-109, 241-SX- 111, 241-SX-112, 241-SX-113, 241-SX-114 and 241-SX-115. The method used to identify leak location consisted of reviewing in-tank and ex-tank leak detection information. This provided the basic data identifying where and when the first leaks were detected. In-tank leak detection consisted of liquid level measurement that can be augmented with photographs which can provide an indication of the vertical leak location on the sidewall. Ex-tank leak detection for the leaking tanks consisted of soil radiation data from laterals and dry-wells near the tank. The in-tank and ex-tank leak detection can provide an indication of the possible leak location radially around and under the tank. Potential leak causes were determined using in-tank and ex-tank information that is not directly related to

  5. Interplay of a non-conjugative integrative element and a conjugative plasmid in the spread of antibiotic resistance via suicidal plasmid transfer from an aquaculture Vibrio isolate.

    Science.gov (United States)

    Nonaka, Lisa; Yamamoto, Tatsuya; Maruyama, Fumito; Hirose, Yuu; Onishi, Yuki; Kobayashi, Takeshi; Suzuki, Satoru; Nomura, Nobuhiko; Masuda, Michiaki; Yano, Hirokazu

    2018-01-01

    The capture of antimicrobial resistance genes (ARGs) by mobile genetic elements (MGEs) plays a critical role in resistance acquisition for human-associated bacteria. Although aquaculture environments are recognized as important reservoirs of ARGs, intra- and intercellular mobility of MGEs discovered in marine organisms is poorly characterized. Here, we show a new pattern of interspecies ARGs transfer involving a 'non-conjugative' integrative element. To identify active MGEs in a Vibrio ponticus isolate, we conducted whole-genome sequencing of a transconjugant obtained by mating between Escherichia coli and Vibrio ponticus. This revealed integration of a plasmid (designated pSEA1) into the chromosome, consisting of a self-transmissible plasmid backbone of the MOBH group, ARGs, and a 13.8-kb integrative element Tn6283. Molecular genetics analysis suggested a two-step gene transfer model. First, Tn6283 integrates into the recipient chromosome during suicidal plasmid transfer, followed by homologous recombination between the Tn6283 copy in the chromosome and that in the newly transferred pSEA1. Tn6283 is unusual among integrative elements in that it apparently does not encode transfer function and its excision barely generates unoccupied donor sites. Thus, its movement is analogous to the transposition of insertion sequences rather than to that of canonical integrative and conjugative elements. Overall, this study reveals the presence of a previously unrecognized type of MGE in a marine organism, highlighting diversity in the mode of interspecies gene transfer.

  6. Assessment of the integrity of degraded steam generator tube by the use of heterogeneous finite element method

    International Nuclear Information System (INIS)

    Duan, X.; Kozluk, M.; Pagan, S.; Mills, B.

    2006-01-01

    Steam generator tubes at Ontario Power Generation (OPG) have been experiencing a variety of degradations such as pitting, fretting wear, erosion-corrosion, thinning and denting. To assist with steam generator life cycle management, OPG has developed Fitness-For-Service Guidelines (FFSG) for steam generator tubes. The FFSG are intended to provide standard acceptance criteria and evaluation procedures for assessing the condition of steam generator tubes for structural integrity, operational leak rate, and consequential leakage during an upset or abnormal event. Based on inspection results in conjunction with representative, postulated distributions of flaws in the un-inspected tubes, the FFSG provide an acceptable method of satisfying the intent of CSA-N285.4 and justifying the continued operation of degraded steam generator tubes. Some non-mandatory empirical axial and circumferential flaw models are also provided in the FFSG for structural integrity assessments. The test data from the OPG Steam Generator Tube Test Program (SGTTP) showed that the FFSG axial flaw model is conservative for a wide range of defect morphologies. A defect-specific axial flaw model was proposed for lattice-bar fret defects in I800 tubes by utilizing the SGTTP database of extensive test results. A defect-specific flaw model for outer diameter (OD) pitting and inner diameter (ID) intergranular attack in Monel 400 tubes was also developed using the SGTTP test data. More tests have been scheduled to support the development of defect specific models for axial flaws (OD cracks or ID laps) in Monel 400 and to supplement the database for Monel 400 pits. This paper explores the use of simulated testing for use in developing defect specific flaw models to reduce the amount of expensive tests. The Heterogeneous Finite Element Model (HFEM) has been developed and successfully applied to predict the failure behaviour of ductile metals under various deformation modes, i.e. plane stress, plane strain and

  7. Integrated survey of elemental stoichiometry (C, N, P from the western to eastern Mediterranean Sea

    Directory of Open Access Journals (Sweden)

    M. Pujo-Pay

    2011-04-01

    Full Text Available This paper provides an extensive vertical and longitudinal description of the biogeochemistry along an East-West transect of 3000 km across the Mediterranean Sea during summer 2008 (BOUM cruise. During this period of strong stratification, the distribution of nutrients, particulate and dissolved organic carbon (DOC, nitrogen (DON and phosphorus (DOP were examined to produce a detailed spatial and vertically extended description of the elemental stoichiometry of the Mediterranean Sea. Surface waters were depleted in nutrients and the thickness of this depleted layer increased towards the East from about 10 m in the Gulf of Lion to more than 100 m in the Levantine basin, with the phosphacline deepening to a greater extent than that for corresponding nitracline and thermocline depths. We used the minimum oxygen concentration through the water column in combination with 2 fixed concentrations of dissolved oxygen to distinguish an intermediate layer (Mineralization Layer; ML from surface (Biogenic Layer; BL, and deep layers (DL. Whilst each layer was represented by different water masses, this approach allowed us to propose a schematic box-plot representation of the biogeochemical functioning of the two Mediterranean basins. Despite the increasing oligotrophic nature and the degree of P-depletion along the West to East gradient strong similarities were encountered between eastern and western ecosystems. Within the BL, the C:N:P ratios in all pools largely exceeded the Redfield ratios, but surprisingly, the nitrate vs. phosphate ratios in the ML and DL tended towards the canonical Redfield values in both basins. A change in particulate matter composition has been identified by a C increase relative to N and P along the whole water column in the western basin and between BL and ML in the eastern one. Our data showed a noticeable stability of the DOC:DON ratio (12–13 throughout the Mediterranean Sea. This is in good agreement with a P-limitation of

  8. Elements of an analysis for a deployment and integration strategy for electric renewable energy in France

    International Nuclear Information System (INIS)

    Ruedinger, Andreas

    2016-01-01

    Through a synthesis of research reports and round tables organized by IDDRI in partnership with the German think-tank Agora Energiewende, this study aims to define the issues and contours of a strategic roadmap for the deployment and integration of renewable energy in France: long-term visibility; the need to better take into account the transformation at a regional and European level; regulatory issues, essential for reducing uncertainty and accelerating the deployment of projects; given the capital intensity of RES projects, issues related to instruments aiming at reducing the risks and costs of financing; and finally the challenges for project acceptance at the local level and appropriation of these projects by the different actors. The French Energy Transition Law for Green Growth adopted in 2015 sets a 40% target for the share of renewables in electricity consumption, representing a doubling of their share to be achieved between now and 2030. This implies a need to speed up the development of the renewable sector. An important lever would be the reduction in project implementation time - down from 7 to 8 years in the wind sector - by simplifying administrative procedures and smoothing the grid connection process. Measures such as the single permit and a 18-month deadline for grid connections, provided for in the Energy Transition Law, should be fully enforced, and a consideration of complementary measures aimed at limiting legal disputes and actions could bring additional value. The portfolio-oriented approach to planning - which seeks to establish the share of each technology in the electricity supply - should be eschewed in favor of a more detailed projection of the evolution of the sector and in particular of electricity demand, as new uses for electricity are envisaged and energy efficiency is declared a priority of the transition. A roadmap would thus be available to help improve the credibility of policies implemented as well as the alignment between the

  9. PSA Level 2 as element of an integral safety assessment before plant commissioning

    International Nuclear Information System (INIS)

    Loeffler, H.; Mildenberger, O.; Sonnenkalb, M.; Steinroetter, T.

    2012-01-01

    In Argentina the Central Nuclear Atucha II is near to completion. This is a pressurized heavy water reactor. PSA (Probability Safety Assessment) level 1, level 2 and level 3 have to be performed in order to show compliance with the Argentinean dose limit. Such studies have been done first by the former KWU in the 1980's to get the construction license (FABIAN 1985). Nowadays the plant owner NA-SA performs PSA level 1 and provides information about the core damage states to GRS, who does the subsequent PSA level 2 part. GRS delivers source terms to the environment and the associated frequencies to the Argentinean research institute CNEA, which performs level 3 together with NA-SA. Since GRS is situated in the middle of the chain, interface definition with both ends has been a significant task of the GRS activities. Experience gained during this process will be highlighted in the presentation. The analysis of PSA level 2 proper follows a traditional approach: -) deterministic accident simulation with integral code MELCOR; -) analyses of specific issues which are not covered by MELCOR; and -) probabilistic accident progression analysis with EVNTRE event tree methodology. It appears that MELCOR and EVNTRE and PSA guidelines in general are flexible enough to analyse new or uncommon reactor designs. It also appears that the plant specific design features may require analyses beyond present code capabilities, calling for expert judgment and they can largely determine PSA results. The behaviour of iodine is not yet covered satisfactorily by state-of-the-art models in MELCOR

  10. Finite Element Modelling and Analysis of Damage Detection Methodology in Piezo Electric Sensor and Actuator Integrated Sandwich Cantilever Beam

    Science.gov (United States)

    Pradeep, K. R.; Thomas, A. M.; Basker, V. T.

    2018-03-01

    Structural health monitoring (SHM) is an essential component of futuristic civil, mechanical and aerospace structures. It detects the damages in system or give warning about the degradation of structure by evaluating performance parameters. This is achieved by the integration of sensors and actuators into the structure. Study of damage detection process in piezoelectric sensor and actuator integrated sandwich cantilever beam is carried out in this paper. Possible skin-core debond at the root of the cantilever beam is simulated and compared with undamaged case. The beam is actuated using piezoelectric actuators and performance differences are evaluated using Polyvinylidene fluoride (PVDF) sensors. The methodology utilized is the voltage/strain response of the damaged versus undamaged beam against transient actuation. Finite element model of piezo-beam is simulated in ANSYSTM using 8 noded coupled field element, with nodal degrees of freedoms are translations in the x, y directions and voltage. An aluminium sandwich beam with a length of 800mm, thickness of core 22.86mm and thickness of skin 0.3mm is considered. Skin-core debond is simulated in the model as unmerged nodes. Reduction in the fundamental frequency of the damaged beam is found to be negligible. But the voltage response of the PVDF sensor under transient excitation shows significantly visible change indicating the debond. Piezo electric based damage detection system is an effective tool for the damage detection of aerospace and civil structural system having inaccessible/critical locations and enables online monitoring possibilities as the power requirement is minimal.

  11. The Integration of Geotechnologies in the Evaluation of a Wine Cellar Structure through the Finite Element Method

    Directory of Open Access Journals (Sweden)

    Alberto Villarino

    2014-11-01

    Full Text Available This paper presents a multidisciplinary methodology to evaluate an underground wine cellar structure using non-invasive techniques. In particular, a historical subterranean wine cellar that presents a complex structure and whose physical properties are unknown is recorded and analyzed using geomatics and geophysics synergies. To this end, an approach that integrates terrestrial laser scanning and ground penetrating radar is used to properly define a finite element-based structural model, which is then used as a decision tool to plan architectural restoration actions. The combination of both techniques implies the registration of external and internal information that eases the construction of structural models. Structural simulation for both stresses and deformations through FEM allowed identifying critical structural elements under great stress or excessive deformations. In this investigation, the ultimate limit state of cracking was considered to determine allowable loads due to the brittle nature of the material. This allowed us to set limit values of loading on the cellar structure in order to minimize possible damage.

  12. ICEApl1, an integrative conjugative element related to ICEHin1056, identified in the pig pathogen Actinobacillus pleuropneumoniae

    Directory of Open Access Journals (Sweden)

    Janine T Bosse

    2016-06-01

    Full Text Available ICEApl1 was identified in the whole genome sequence of MIDG2331, a tetracycline-resistant (MIC = 8 mg/L serovar 8 clinical isolate of Actinobacillus pleuropneumoniae, the causative agent of porcine pleuropneumonia. PCR amplification of virB4, one of the core genes involved in conjugation, was used to identify other A. pleuropneumoniae isolates potentially carrying ICEApl1. MICs for tetracycline were determined for virB4 positive isolates, and shotgun whole genome sequence analysis was used to confirm presence of the complete ICEApl1. The sequence of ICEApl1 is 56083 bp long and contains 67 genes including a Tn10 element encoding tetracycline resistance. Comparative sequence analysis was performed with similar integrative conjugative elements (ICEs found in other members of the Pasteurellaceae. ICEApl1 is most similar to the 59393 bp ICEHin1056, from Haemophilus influenzae strain 1056. Although initially identified only in serovar 8 isolates of A. pleuropneumoniae (31 from the UK and 1 from Cyprus, conjugal transfer of ICEApl1 to representative isolates of other serovars was confirmed. All isolates carrying ICEApl1 had a MIC for tetracycline of 8 mg/L. This is, to our knowledge, the first description of an ICE in A. pleuropneumoniae, and the first report of a member of the ICEHin1056 subfamily in a non-human pathogen. ICEApl1 confers resistance to tetracycline, currently one of the more commonly used antibiotics for treatment and control of porcine pleuropneumonia.

  13. Finite element modeling for integrated solid-solid PCM-building material with varying phase change temperatures

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, D.; Fung, A.S.; Siddiqui, O. [Ryerson Polytechnic Univ., Toronto, ON (Canada). Dept. of Mechanical and Industrial Engineering

    2008-08-15

    Solid-solid phase change materials (SSPCMs) are used to enhance thermal storage performance and reduce indoor temperature fluctuations in buildings. In this study, a finite element model (FEM) was used to investigate the thermal properties of different types of SSPCMs. An effective heat capacity method was used to develop the model. An integrated PCM-building material was analyzed in relation to temperature and heat flux profiles. Governing equations for the heat transfer process were composed of Navier-Stokes momentum equations; a mass conservation equation; and an energy conservation equation. Effective heat capacity was described as a linear function of the latent heat of fusion on both the heating and cooling processes. Data from the simulation were then compared with an experiment suing drywall, concrete and gypcrete samples. Heat flux across the surfaces and temperatures on the surfaces of the materials were measured. Data were used to validate the finite element model (FEM). Results of the study suggested that heat flux profiles are an effective means of understanding phase change processes. It was concluded that PCMs with lower phase change temperatures lengthened energy releases and improved thermal comfort in the building. 12 refs., 2 tabs., 14 figs.

  14. Finite element modeling simulation-assisted design of integrated microfluidic chips for heavy metal ion stripping analysis

    International Nuclear Information System (INIS)

    Hong, Ying; Zou, Jianhua; Ge, Gang; Xiao, Wanyue; Shao, Jinjun; Dong, Xiaochen; Gao, Ling

    2017-01-01

    In this article, a transparent integrated microfluidic device composed of a 3D-printed thin-layer flow cell (3D-PTLFC) and an S-shaped screen-printed electrode (SPE) has been designed and fabricated for heavy metal ion stripping analysis. A finite element modeling (FEM) simulation is employed to optimize the shape of the electrode, the direction of the inlet pipeline, the thin-layer channel height and the sample flow rate to enhance the electron-enrichment efficiency for stripping analysis. The results demonstrate that the S-shaped SPE configuration matches the channel in 3D-PTLFC perfectly for the anodic stripping behavior of the heavy metal ions. Under optimized conditions, a wide linear range of 1–80 µ g l −1 is achieved for Pb 2+ detection with a limit of 0.3 µ g l −1 for the microfluidic device. Thus, the obtained integrated microfluidic device proves to be a promising approach for heavy metal ions stripping analysis with low cost and high performance. (paper)

  15. A finite element model for estimating the techno-economic performance of the building-integrated photovoltaic blind

    International Nuclear Information System (INIS)

    Park, Hyo Seon; Koo, Choongwan; Hong, Taehoon; Oh, Jeongyoon; Jeong, Kwangbok

    2016-01-01

    Highlights: • A FEM was developed to estimate the techno-economic performance of the BIPB. • The mean absolute percentage error of the FEM_4_-_n_o_d_eBIPB was determined to be 4.54%. • In implementing the BIPB with the GC_i_n_c_l_._S_R_E_C plan, it was superior to the others. • Users can understand the operating mechanism of the proposed model (FEM_4_-_n_o_d_eBIPB). • The proposed model can be extended to any other country in the global environment. - Abstract: This study aims to develop the four-node-based finite element model for estimating the techno-economic performance of the building-integrated photovoltaic blind (FEM_4_-_n_o_d_eBIPB), which can be used by decision-maker in the early design phase. In developing the proposed model, this study uses various research methodologies such as energy simulation, finite element method, life cycle cost analysis, policy analysis, and visual basic application. Compared to the simulation results, the mean absolute percentage error of the proposed model was determined to be 4.54%, showing that the prediction accuracy of the proposed model was found to be excellent. Furthermore, the practical application was conducted for the ‘S’ elementary school facility in South Korea, which allows potential readers to easily and clearly understand the operating mechanism of the proposed model as well as its usability and extendability. The proposed model can be used to conduct the detailed analysis of the techno-economic performance of the BIPB by the type of utilization plan and to determine the optimal strategy for maximizing the value of the investment. Furthermore, the proposed research framework can be extended to any other technology, industry, and country in the global environment.

  16. Distribution and Genetic Characteristics of SXT/R391 Integrative Conjugative Elements in Shewanella spp. From China

    Directory of Open Access Journals (Sweden)

    Yujie Fang

    2018-05-01

    Full Text Available The genus Shewanella consists of facultatively anaerobic Gram-negative bacteria, which are regarded as potential agents of food contamination and opportunistic human pathogens. Information about the distribution and genetic characteristics of SXT/R391 integrative conjugative elements (ICEs in Shewanella species is limited. Here, 91 Shewanella strains collected from diverse samples in China were studied for the presence of SXT/R391 ICEs. Three positive strains, classified as Shewanella upenei, were obtained from patients and water from a local mill. In light of their close clonal relationships and high sequence similarity, a representative ICE was selected and designated ICESupCHN110003. The BLASTn searches against GenBank showed that ICEVchBan5 was most closely related to ICESupCHN110003, with the coverage of 76% and identity of 99%. The phylogenetic tree of concatenated core genes demonstrated that ICESupCHN110003 formed a distinct branch outside the cluster comprising ICEValA056-1, ICEPmiCHN2410, and ICEPmiChn1. Comparison of the genetic structures revealed that ICESupCHN110003 encoded uncommon genes in hotspots, such as specific type III restriction-modification system, conferring adaptive functions to the host. Based on the low coverage in the sequence analysis, independent clade in the phylogenetic tree, and unique inserted fragments in hotspots, ICESupCHN110003 represented a novel SXT/R391 element, which widened the list of ICEs. Furthermore, the antibiotic resistance genes floR, strA, strB, and sul2 in ICESupCHN110003 and resistance to multiple drugs of the positive isolates were detected. A cross-species transfer capability of the SXT/R391 ICEs was also discovered. In summary, it is necessary to reinforce continuous surveillance of SXT/R391 ICEs in the genus Shewanella.

  17. Inclusion of Moloney murine leukemia virus elements upstream of the transgene cassette in an E1-deleted adenovirus leads to an unusual genomic integration in epithelial cells

    International Nuclear Information System (INIS)

    Zheng Changyu; O'Connell, Brian C.; Baum, Bruce J.

    2003-01-01

    Classically, the 5' and 3' long terminal repeats (LTRs) are considered necessary but not sufficient for retroviral integration. Recently, we reported that inclusion of these and additional elements from Moloney murine leukemia virus (MoMLV) facilitated transgene integration, without retroviral integrase, when placed in an adenoviral context (AdLTR-luc vector) (Nat. Biotech. 18 (2000), 176; Biochem. Biophys. Res. Commun. 300 (2003), 115). To help understand this nonhomologous DNA recombination event, we constructed another vector, AdELP-luc, with 2.7 kb of MoMLV elements identically placed into an E1-deleted adenovirus type 5 backbone upstream of a luciferase cDNA reporter gene. Unlike AdLTR-luc, no MoMLV elements were placed downstream of the expression cassette. AdELP-luc readily infected epithelial cells in vitro. Southern hybridizations with DNA from cloned cells showed that disruption of the MoMLV sequences occurred. One cell clone, grown in vitro without any special selection medium for 9 months, exhibited stable vector integration and luciferase activity. Importantly, both Southern hybridization and FISH analyses showed that in addition to the MoMLV elements and expression cassette, substantial adenoviral sequence downstream of the luciferase cDNA was genomically integrated. These results suggest that the 2.7 kb of MoMLV sequence included in AdELP-luc have cis-acting functions and mediates an unusual integration event

  18. A conserved helicase processivity factor is needed for conjugation and replication of an integrative and conjugative element.

    Directory of Open Access Journals (Sweden)

    Jacob Thomas

    Full Text Available Integrative and conjugative elements (ICEs are agents of horizontal gene transfer and have major roles in evolution and acquisition of new traits, including antibiotic resistances. ICEs are found integrated in a host chromosome and can excise and transfer to recipient bacteria via conjugation. Conjugation involves nicking of the ICE origin of transfer (oriT by the ICE-encoded relaxase and transfer of the nicked single strand of ICE DNA. For ICEBs1 of Bacillus subtilis, nicking of oriT by the ICEBs1 relaxase NicK also initiates rolling circle replication. This autonomous replication of ICEBs1 is critical for stability of the excised element in growing cells. We found a conserved and previously uncharacterized ICE gene that is required for conjugation and replication of ICEBs1. Our results indicate that this gene, helP (formerly ydcP, encodes a helicase processivity factor that enables the host-encoded helicase PcrA to unwind the double-stranded ICEBs1 DNA. HelP was required for both conjugation and replication of ICEBs1, and HelP and NicK were the only ICEBs1 proteins needed for replication from ICEBs1 oriT. Using chromatin immunoprecipitation, we measured association of HelP, NicK, PcrA, and the host-encoded single-strand DNA binding protein Ssb with ICEBs1. We found that NicK was required for association of HelP and PcrA with ICEBs1 DNA. HelP was required for association of PcrA and Ssb with ICEBs1 regions distal, but not proximal, to oriT, indicating that PcrA needs HelP to progress beyond nicked oriT and unwind ICEBs1. In vitro, HelP directly stimulated the helicase activity of the PcrA homologue UvrD. Our findings demonstrate that HelP is a helicase processivity factor needed for efficient unwinding of ICEBs1 for conjugation and replication. Homologues of HelP and PcrA-type helicases are encoded on many known and putative ICEs. We propose that these factors are essential for ICE conjugation, replication, and genetic stability.

  19. Elements of mathematics integration

    CERN Document Server

    Bourbaki, Nicolas

    2004-01-01

    Intégration is the sixth and last of the Books that form the core of the Bourbaki series; it draws abundantly on the preceding five Books, especially General Topology and Topological Vector Spaces, making it a culmination of the core six. The power of the tool thus fashioned is strikingly displayed in Chapter II of the author's Théories Spectrales, an exposition, in a mere 38 pages, of abstract harmonic analysis and the structure of locally compact abelian groups. The present volume comprises Chapters 1-6 in English translation (a second volume will contain the remaining Chapters 7-9). The individual fascicles of the original French edition have been extensively reviewed. Chapters 1-5 received very substantial revisions in a second edition, including changes to some fundamental definitions. Chapters 6-8 are based on the first editions of Chs. 1-5. The English edition has given the author the opportunity to correct misprints, update references, clarify the concordance of Chapter 6 with the second editions of...

  20. Theoretical and methodological elements for integrating ethics as a foundation into the education of professional and design disciplines.

    Science.gov (United States)

    d'Anjou, Philippe

    2004-04-01

    The paper addresses the integration of ethics into professional education related to the disciplines responsible for the conception and creation of the artificial (artefactual or technology). The ontological-epistemological paradigm of those disciplines is understood within the frame of the sciences of the artificial as established by Herbert Simon (1969). According to that paradigm, those sciences include disciplines not only related to the production of artefacts (technology), such as engineering, architecture, industrial design, etc, but also disciplines related to devised courses of action aimed at changing existing situations into preferred ones, like medicine, law, education, etc. They are centered on intentional action and at their core is the activity of design, which is their common foundation and attitude, or their common culture. The science of design becomes the broader foundational discipline for any professions engaged in the intentional transformation of the world. The main distinction between design disciplines and scientific ones rests on the object-project dichotomy. Indeed, contrary to Science that sees the world as an object to be observed, Design sees the world as a project and acts upon the world through projects, which are grounded in intentions, ends, and values. Design disciplines are meant to transform the world, or part of it, and are teleological. Being so, they are embodied in an act that is ethical and their ontology-epistemology must be addressed also through practical reason to resituate all professional disciplines according to their involved nature. The paper introduces theoretical, methodological, and ethical elements to establish a model that integrates ethics into the education of the professional disciplines, design-based disciplines, responsible for the creation of the artificial, artefactual or technological, world. The model is articulated around the notions of ethical engagement and responsibility through the act of design

  1. Yeast cytochrome c integrated with electronic elements: a nanoscopic and spectroscopic study down to single-molecule level

    International Nuclear Information System (INIS)

    Delfino, I; Bonanni, B; Andolfi, L; Baldacchini, C; Bizzarri, A R; Cannistraro, S

    2007-01-01

    Various aspects of redox protein integration with nano-electronic elements are addressed by a multi-technique investigation of different yeast cytochrome c (YCC)-based hybrid systems. Three different immobilization strategies on gold via organic linkers are explored, involving either covalent bonding or electrostatic interaction. Specifically, Au surfaces are chemically modified by self-assembled monolayers (SAMs) exposing thiol-reactive groups, or by acid-oxidized single-wall carbon nanotubes (SWNTs). Atomic force microscopy and scanning tunnelling microscopy are employed to characterize the morphology and the electronic properties of single YCC molecules adsorbed on the modified gold surfaces. In each hybrid system, the protein molecules are stably assembled, in a native configuration. A standing-up arrangement of YCC on SAMs is suggested, together with an enhancement of the molecular conduction, as compared to YCC directly assembled on gold. The electrostatic interaction with functionalized SWNTs allows several YCC adsorption geometries, with a preferential high-spin haem configuration, as outlined by Raman spectroscopy. Moreover, the conduction properties of YCC, explored in different YCC nanojunctions by conductive atomic force microscopy, indicate the effectiveness of electrical conduction through the molecule and its dependence on the electrode material. The joint employment of several techniques confirms the key role of a well-designed immobilization strategy, for optimizing biorecognition capabilities and electrical coupling with conductive substrates at the single-molecule level, as a starting point for advanced applications in nano-biotechnology

  2. One electronic document accepted by importer and exporter authorities: Blue Path as an element of integration and traceability

    Directory of Open Access Journals (Sweden)

    Scoton Maria L. R. P. D.

    2016-01-01

    Full Text Available The Blue Path (CA-e is an document created and transmitted electronically that contains all necessary data to allow the sanitary authority to analyze the requirement of exportation that will result on the sanitary clearance of the animal protein for exportation. Actually it is in use in Brazil. However, even though the data exists electronically, when it is send to the importer country some must be sent on paper, because the bilateral agreements do not allow the exchange of electronic documents. The present work proposals the extension of the CA-e, as an element of integration and traceability, that will allow the automation of the communication between private and public systems not only at Brazil, the country of the origin of the animal protein exported, but also between and at the country of destiny. Based on the number presented by the adoption of the CA-e at Brazil, it is fair to conclude that this communication machine/machine would bring great economy and optimization for the supply chain.

  3. An analytical boundary element integral approach to track the boundary of a moving cavity using electrical impedance tomography

    International Nuclear Information System (INIS)

    Khambampati, Anil Kumar; Kim, Sin; Lee, Bo An; Kim, Kyung Youn

    2012-01-01

    This paper is about locating the boundary of a moving cavity within a homogeneous background from the voltage measurements recorded on the outer boundary. An inverse boundary problem of a moving cavity is formulated by considering a two-phase vapor–liquid flow in a pipe. The conductivity of the flow components (vapor and liquid) is assumed to be constant and known a priori while the location and shape of the inclusion (vapor) are the unknowns to be estimated. The forward problem is solved using the boundary element method (BEM) with the integral equations solved analytically. A special situation is considered such that the cavity changes its location and shape during the time taken to acquire a full set of independent measurement data. The boundary of a cavity is assumed to be elliptic and is parameterized with Fourier series. The inverse problem is treated as a state estimation problem with the Fourier coefficients that represent the center and radii of the cavity as the unknowns to be estimated. An extended Kalman filter (EKF) is used as an inverse algorithm to estimate the time varying Fourier coefficients. Numerical experiments are shown to evaluate the performance of the proposed method. Through the results, it can be noticed that the proposed BEM with EKF method is successful in estimating the boundary of a moving cavity. (paper)

  4. Numerical study on two-point contact by an explicit integration finite element method : A contribution to the modeling of flange squeal

    NARCIS (Netherlands)

    Yang, Z.; Li, Z.; Dollevoet, R.P.B.J.; Tournay, H; Grassie, S

    2015-01-01

    The precise mechanism which activates squeal, especially flange squeal has not been fully explained. The complex non-Hertzian contact and the broad-band high frequency feature bring great challenges to the modelling work of flange squeal. In this paper, an explicit integration finite element method

  5. A boundary integral method for numerical computation of radar cross section of 3D targets using hybrid BEM/FEM with edge elements

    Science.gov (United States)

    Dodig, H.

    2017-11-01

    This contribution presents the boundary integral formulation for numerical computation of time-harmonic radar cross section for 3D targets. Method relies on hybrid edge element BEM/FEM to compute near field edge element coefficients that are associated with near electric and magnetic fields at the boundary of the computational domain. Special boundary integral formulation is presented that computes radar cross section directly from these edge element coefficients. Consequently, there is no need for near-to-far field transformation (NTFFT) which is common step in RCS computations. By the end of the paper it is demonstrated that the formulation yields accurate results for canonical models such as spheres, cubes, cones and pyramids. Method has demonstrated accuracy even in the case of dielectrically coated PEC sphere at interior resonance frequency which is common problem for computational electromagnetic codes.

  6. Dynamical analysis of a PWR internals using super-elements in an integrated 3-D model model. Part 1: model description and static tests

    International Nuclear Information System (INIS)

    Jesus Miranda, C.A. de.

    1992-01-01

    An integrated 3-D model of a research PWR reactor core support internals structures was developed for its dynamic analyses. The static tests for the validation of the model are presented. There are about 90 super-elements with, approximately, 85000 degrees of freedom (DoF), 8200 masters DoF, 12000 elements with about 8400 thin shell elements. A DEC VAX computer 11/785 model and the ANSYS program were used. If impacts occurs the spectral seismic analysis will be changed to a non-linear one with direct integration of the displacement pulse derived from the seismic accelerogram. This last will be obtained from the seismic acceleration response spectra. (author)

  7. Selection Ideal Coal Suppliers of Thermal Power Plants Using the Matter-Element Extension Model with Integrated Empowerment Method for Sustainability

    Directory of Open Access Journals (Sweden)

    Zhongfu Tan

    2014-01-01

    Full Text Available In order to reduce thermal power generation cost and improve its market competitiveness, considering fuel quality, cost, creditworthiness, and sustainable development capacity factors, this paper established the evaluation system for coal supplier selection of thermal power and put forward the coal supplier selection strategies for thermal power based on integrated empowering and ideal matter-element extension models. On the one hand, the integrated empowering model can overcome the limitations of subjective and objective methods to determine weights, better balance subjective, and objective information. On the other hand, since the evaluation results of the traditional element extension model may fall into the same class and only get part of the order results, in order to overcome this shortcoming, the idealistic matter-element extension model is constructed. It selects the ideal positive and negative matter-elements classical field and uses the closeness degree to replace traditional maximum degree of membership criterion and calculates the positive or negative distance between the matter-element to be evaluated and the ideal matter-element; then it can get the full order results of the evaluation schemes. Simulated and compared with the TOPSIS method, Romania selection method, and PROMETHEE method, numerical example results show that the method put forward by this paper is effective and reliable.

  8. Parametric study of the low-enriched uranium integrated Fort-Saint-Vrain element; comparative evaluation with the interacting tubular element

    International Nuclear Information System (INIS)

    Cerles, J.M.; Carvallo, G.; Vallepin, C.

    1971-11-01

    This paper presents a study of the influence of the different geometric and neutronic parameters on the calculation of the cycle with low-enriched uranium in a Fort-Saint-Vrain type brick. The study is divided in two parts: a stage of physics, essentially neutronics; an economical part where the costs are taken into account. At the level of studies of neutronics and costs, a parallel comparison is developed between the brick Fort-Saint-Vrain and the interacting tubular element, and even thorium. 6 refs. 29 figs [fr

  9. Integration of auto analysis program of gamma spectrum and software and determination of element content in sample by k-zero method

    International Nuclear Information System (INIS)

    Trinh Quang Vinh; Truong Thi Hong Loan; Mai Van Nhon; Huynh Truc Phuong

    2014-01-01

    Integrating the gamma spectrum auto-analysis program with elemental analysis software by k-zero method is the objective for many researchers. This work is the first stepin building an auto analysis program of gamma spectrum, which includes modules of reading spectrum, displaying spectrum, calibrating energy of peak, smoothing spectrum, calculating peak area and determining content of elements in sample. Then, the results from the measurements of standard samples by a low level spectrometer using HPGe detector are compared to those of other gamma spectrum auto-analysis programs. (author)

  10. A novel Sulfolobus non-conjugative extrachromosomal genetic element capable of integration into the host genome and spreading in the presence of a fusellovirus

    DEFF Research Database (Denmark)

    Wang, Ying; Duan, Zhenhong; Zhu, Haojun

    2007-01-01

    An integrative non-conjugative extrachromosomal genetic element, denoted as pSSVi, has been isolated from a Sulfolobus solfataricus P2 strain and was characterized. This genetic element is a double-stranded DNA of 5740 bp in size and contains eight open reading frames (ORFs). It resembles members....... Interestingly, pSSVi encodes an SSV-type integrase which probably catalyzes the integration of its genome into a specific site (a tRNA(Arg) gene) in the S. solfataricus P2 genome. Like pSSVx, pSSVi can be packaged into a spindle-like viral particle and spread with the help of SSV1 or SSV2. In addition, both SSV......1 and SSV2 appeared to replicate more efficiently in the presence of pSSVi. Given the versatile genetic abilities, pSSVi appears to be well suited for a role in horizontal gene transfer....

  11. Information Environment is an Integral Element of Informational Space in the Process of Professional Development of Future Teacher of Physical Culture

    Directory of Open Access Journals (Sweden)

    Yuri V. Dragnev

    2012-04-01

    Full Text Available The article examines information environment as an integral element of information space in the process of professional development of future teacher of physical culture, notes that the strategic objective of the system of higher education is training of competent future teacher of physical culture in the field of information technologies, when information competence and information culture are major components of professionalism in modern information-oriented society

  12. SCREEN FOR DOMINANT BEHAVIORAL MUTATIONS CAUSED BY GENOMIC INSERTION OF P-ELEMENT TRANSPOSONS IN DROSOPHILA: AN EXAMINATION OF THE INTEGRATION OF VIRAL VECTOR SEQUENCES

    OpenAIRE

    FOX, LYLE E.; GREEN, DAVID; YAN, ZIYING; ENGELHARDT, JOHN F.; WU, CHUN-FANG

    2007-01-01

    Here we report the development of a high-throughput screen to assess dominant mutation rates caused by P-element transposition within the Drosophila genome that is suitable for assessing the undesirable effects of integrating foreign regulatory sequences (viral cargo) into a host genome. Three different behavioral paradigms were used: sensitivity to mechanical stress, response to heat stress, and ability to fly. The results, from our screen of 35,000 flies, indicate that mutations caused by t...

  13. Integrated chemical sensor array platform based on a light emitting diode, xerogel-derived sensor elements, and high-speed pin printing

    International Nuclear Information System (INIS)

    Cho, Eun Jeong; Bright, Frank V.

    2002-01-01

    We report a new, solid-state, integrated optical array sensor platform. By using pin printing technology in concert with sol-gel-processing methods, we form discrete xerogel-based microsensor elements that are on the order of 100 μm in diameter and 1 μm thick directly on the face of a light emitting diode (LED). The LED serves as the light source to excite chemically responsive luminophores sequestered within the doped xerogel microsensors and the analyte-dependent emission from within the doped xerogel is detected with a charge coupled device (CCD). We overcome the problem of background illumination from the LED reaching the CCD and the associated biasing that results by coating the LED first with a thin layer of blue paint. The thin paint layer serves as an optical filter, knocking out the LEDs red-edge spectral tail. The problem of the spatially-dependent fluence across the LED face is solved entirely by performing ratiometric measurements. We illustrate the performance of the new sensor scheme by forming an array of 100 discrete O 2 -responsive sensing elements on the face of a single LED. The combination of pin printing with an integrated sensor and light source platform results in a rapid method of forming (∼1 s per sensor element) reusable sensor arrays. The entire sensor array can be calibrated using just one sensor element. Array-to-array reproducibly is <8%. Arrays can be formed using single or multiple pins with indistinguishable analytical performance

  14. Deciphering the genomes of 16 Acanthamoeba species does not provide evidence of integration of known giant virus-associated mobile genetic elements.

    Science.gov (United States)

    Chelkha, Nisrine; Colson, Philippe; Levasseur, Anthony; La Scola, Bernard

    2018-06-02

    Giant viruses infect protozoa, especially amoebae of the genus Acanthamoeba. These viruses possess genetic elements named Mobilome. So far, this mobilome comprises provirophages which are integrated into the genome of their hosts, transpovirons, and Maverick/Polintons. Virophages replicate inside virus factories within Acanthamoeba and can decrease the infectivity of giant viruses. The virophage infecting CroV was found to be integrated in the host of CroV, Cafeteria roenbergensis, thus protecting C. roenbergensis by reduction of CroV multiplication. Because of this unique property, assessment of the mechanisms of replication of virophages and their relationship with giant viruses is a key element of this investigation. This work aimed at evaluating the presence and the dynamic of these mobile elements in sixteen Acanthamoeba genomes. No significant traces of the integration of genomes or sequences from known virophages were identified in all the available Acanthamoeba genomes. These results brought us to hypothesize that the interactions between mimiviruses and their virophages might occur through different mechanisms, or at low frequency. An additional explanation could be that our knowledge of the diversity of virophages is still very limited. Copyright © 2018 Elsevier B.V. All rights reserved.

  15. Integrative study of the behavior of transuranic elements in the marine environment. Progress report, June 1, 1981-May 31, 1982

    International Nuclear Information System (INIS)

    Choppin, G.R.; Morse, J.W.

    1981-12-01

    The laboratory at Florida State University is conducting fundamental research under marine conditions of the speciation of actinide elements in sea water. At the Texas A and M University, the adsorption of actinides from such solutions upon various components of sediments is being studied. This approach should yield radiochemical data directly applicable to the understanding of the distribution and speciation of transuranic elements in the marine environment. A limited number of common sediment components are being studied to determine which factors determine the partitioning of transuranic elements among these components. The individual components then will be combined in synthetic sediments of increasing complexity and the distributions studied between these sediments and solutions. Hopefully, this will lead to studies agreeing with model predictions for the adsorption of transuranic elements in marine sediments

  16. Integration

    DEFF Research Database (Denmark)

    Emerek, Ruth

    2004-01-01

    Bidraget diskuterer de forskellige intergrationsopfattelse i Danmark - og hvad der kan forstås ved vellykket integration......Bidraget diskuterer de forskellige intergrationsopfattelse i Danmark - og hvad der kan forstås ved vellykket integration...

  17. Applications of condensed matter understanding to medical tissues and disease progression: Elemental analysis and structural integrity of tissue scaffolds

    Energy Technology Data Exchange (ETDEWEB)

    Bradley, D.A., E-mail: d.a.bradley@surrey.ac.u [Centre for Nuclear and Radiation Physics, Department of Physics, University of Surrey, Guildford GU2 7XH (United Kingdom); Farquharson, M.J. [Department of Radiography, School of Community and Health Sciences, City University, London (United Kingdom); Gundogdu, O. [Centre for Nuclear and Radiation Physics, Department of Physics, University of Surrey, Guildford GU2 7XH (United Kingdom); Al-Ebraheem, Alia [Department of Radiography, School of Community and Health Sciences, City University, London (United Kingdom); Che Ismail, Elna [Centre for Nuclear and Radiation Physics, Department of Physics, University of Surrey, Guildford GU2 7XH (United Kingdom); Kaabar, W., E-mail: w.kaabar@surrey.ac.u [Centre for Nuclear and Radiation Physics, Department of Physics, University of Surrey, Guildford GU2 7XH (United Kingdom); Bunk, O. [Paul Scherrer Institute, CH-5232 Villigen (Switzerland); Pfeiffer, F. [Paul Scherrer Institute, CH-5232 Villigen (Switzerland); Ecole Polytechnique Federale de Lausanne, CH-1015 Lausanne (Switzerland); Falkenberg, G. [Hamburger Synchrotronstrahlungslabor HASYLAB at Deutsches Elektronensynchrotron DESY, Notkestr. 85, D-22603 Hamburg (Germany); Bailey, M. [Surrey Ion Beam Centre, Advanced Technology Institute, University of Surrey, Guildford GU2 7XH (United Kingdom)

    2010-02-15

    The investigations reported herein link tissue structure and elemental presence with issues of environmental health and disease, exemplified by uptake and storage of potentially toxic elements in the body, the osteoarthritic condition and malignancy in the breast and other soft tissues. Focus is placed on application of state-of-the-art ionizing radiation techniques, including, micro-synchrotron X-ray fluorescence (mu-SXRF) and particle-induced X-ray emission/Rutherford backscattering mapping (mu-PIXE/RBS), coherent small-angle X-ray scattering (cSAXS) and X-ray phase-contrast imaging, providing information on elemental make-up, the large-scale organisation of collagen and anatomical features of moderate and low atomic number media. For the particular situations under investigation, use of such facilities is allowing information to be obtained at an unprecedented level of detail, yielding new understanding of the affected tissues and the progression of disease.

  18. Applications of condensed matter understanding to medical tissues and disease progression: Elemental analysis and structural integrity of tissue scaffolds

    International Nuclear Information System (INIS)

    Bradley, D.A.; Farquharson, M.J.; Gundogdu, O.; Al-Ebraheem, Alia; Che Ismail, Elna; Kaabar, W.; Bunk, O.; Pfeiffer, F.; Falkenberg, G.; Bailey, M.

    2010-01-01

    The investigations reported herein link tissue structure and elemental presence with issues of environmental health and disease, exemplified by uptake and storage of potentially toxic elements in the body, the osteoarthritic condition and malignancy in the breast and other soft tissues. Focus is placed on application of state-of-the-art ionizing radiation techniques, including, micro-synchrotron X-ray fluorescence (μ-SXRF) and particle-induced X-ray emission/Rutherford backscattering mapping (μ-PIXE/RBS), coherent small-angle X-ray scattering (cSAXS) and X-ray phase-contrast imaging, providing information on elemental make-up, the large-scale organisation of collagen and anatomical features of moderate and low atomic number media. For the particular situations under investigation, use of such facilities is allowing information to be obtained at an unprecedented level of detail, yielding new understanding of the affected tissues and the progression of disease.

  19. Elastic-Plastic J-Integral Solutions or Surface Cracks in Tension Using an Interpolation Methodology. Appendix C -- Finite Element Models Solution Database File, Appendix D -- Benchmark Finite Element Models Solution Database File

    Science.gov (United States)

    Allen, Phillip A.; Wells, Douglas N.

    2013-01-01

    No closed form solutions exist for the elastic-plastic J-integral for surface cracks due to the nonlinear, three-dimensional nature of the problem. Traditionally, each surface crack must be analyzed with a unique and time-consuming nonlinear finite element analysis. To overcome this shortcoming, the authors have developed and analyzed an array of 600 3D nonlinear finite element models for surface cracks in flat plates under tension loading. The solution space covers a wide range of crack shapes and depths (shape: 0.2 less than or equal to a/c less than or equal to 1, depth: 0.2 less than or equal to a/B less than or equal to 0.8) and material flow properties (elastic modulus-to-yield ratio: 100 less than or equal to E/ys less than or equal to 1,000, and hardening: 3 less than or equal to n less than or equal to 20). The authors have developed a methodology for interpolating between the goemetric and material property variables that allows the user to reliably evaluate the full elastic-plastic J-integral and force versus crack mouth opening displacement solution; thus, a solution can be obtained very rapidly by users without elastic-plastic fracture mechanics modeling experience. Complete solutions for the 600 models and 25 additional benchmark models are provided in tabular format.

  20. Heat Storage Performance of the Prefabricated Hollow Core Concrete Deck Element with Integrated Microencapsulated Phase Change Material

    DEFF Research Database (Denmark)

    Pomianowski, Michal Zbigniew; Heiselberg, Per; Jensen, Rasmus Lund

    2012-01-01

    The paper presents the numerically calculated dynamic heat storage capacity of the prefabricated hollow core concrete deck element with and without microencapsulated phase change material (PCM). The reference deck is the ordinary deck made of standard concrete material and that is broadly used...

  1. Spontaneous germline excision of Tol1, a DNA-based transposable element naturally occurring in the medaka fish genome.

    Science.gov (United States)

    Watanabe, Kohei; Koga, Hajime; Nakamura, Kodai; Fujita, Akiko; Hattori, Akimasa; Matsuda, Masaru; Koga, Akihiko

    2014-04-01

    DNA-based transposable elements are ubiquitous constituents of eukaryotic genomes. Vertebrates are, however, exceptional in that most of their DNA-based elements appear to be inactivated. The Tol1 element of the medaka fish, Oryzias latipes, is one of the few elements for which copies containing an undamaged gene have been found. Spontaneous transposition of this element in somatic cells has previously been demonstrated, but there is only indirect evidence for its germline transposition. Here, we show direct evidence of spontaneous excision in the germline. Tyrosinase is the key enzyme in melanin biosynthesis. In an albino laboratory strain of medaka fish, which is homozygous for a mutant tyrosinase gene in which a Tol1 copy is inserted, we identified de novo reversion mutations related to melanin pigmentation. The gamete-based reversion rate was as high as 0.4%. The revertant fish carried the tyrosinase gene from which the Tol1 copy had been excised. We previously reported the germline transposition of Tol2, another DNA-based element that is thought to be a recent invader of the medaka fish genome. Tol1 is an ancient resident of the genome. Our results indicate that even an old element can contribute to genetic variation in the host genome as a natural mutator.

  2. Integration of heterologous DNA into the genome of Paracoccus denitrificans is mediated by a family of IS1248-related elements and a second type of integrative recombination event

    NARCIS (Netherlands)

    Van Spanning, R J; Reijnders, W N; Stouthamer, A.H.

    All members of the IS1248 family residing in the genome of Paracoccus denitrificans have been isolated by using a set of insertion sequence entrapment vectors. The family consists of five closely related members that integrate the entrapment vectors at distinct sites. One of these, IS1248b, was

  3. Potential for thermochemical conversion of biomass residues from the integrated sugar-ethanol process - Fate of ash and ash-forming elements.

    Science.gov (United States)

    Dirbeba, Meheretu Jaleta; Brink, Anders; DeMartini, Nikolai; Zevenhoven, Maria; Hupa, Mikko

    2017-06-01

    In this work, potential for thermochemical conversion of biomass residues from an integrated sugar-ethanol process and the fate of ash and ash-forming elements in the process are presented. Ash, ash-forming elements, and energy flows in the process were determined using mass balances and analyses of eight different biomass samples for ash contents, elemental compositions, and heating values. The results show that the ash content increases from the sugarcane to the final residue, vinasse. The cane straw, which is left in the field, contains one-third of the energy and 25% of the K and Cl while the vinasse contains 2% of the energy and 40% of the K and Cl in the cane. K and Cl in biomass fuels cause corrosion and fouling problems in boilers and gasifiers. Over 85% of these elements in the straw are water soluble indicating that water leaching would improve it for utilization in thermochemical conversion. Copyright © 2017 Elsevier Ltd. All rights reserved.

  4. Use of geochemical signatures, including rare earth elements, in mosses and lichens to assess spatial integration and the influence of forest environment

    Science.gov (United States)

    Gandois, L.; Agnan, Y.; Leblond, S.; Séjalon-Delmas, N.; Le Roux, G.; Probst, A.

    2014-10-01

    In order to assess the influence of local environment and spatial integration of Trace Metals (TM) by biomonitors, Al, As, Cd, Cr, Cs, Cu, Fe, Mn, Ni, Pb, Sb, Sn, V and Zn and some rare earth element (REE) concentrations have been measured in lichens and mosses collected in three French forest sites located in three distinct mountainous areas, as well as in the local soil and bedrock, and in both bulk deposition (BD) and throughfall (TF). Similar enrichment factors (EF) were calculated using lichens and mosses and local bedrock for most elements, except for Cs, Mn, Ni, Pb, and Cu which were significantly (KW, p leaching (Mn), direct uptake (Ni), or dry deposition dissolution (Pb, Cu, Cs).

  5. Elemental distribution and sample integrity comparison of freeze-dried and frozen-hydrated biological tissue samples with nuclear microprobe

    Energy Technology Data Exchange (ETDEWEB)

    Vavpetič, P., E-mail: primoz.vavpetic@ijs.si [Jožef Stefan Institute, Jamova 39, SI-1000 Ljubljana (Slovenia); Vogel-Mikuš, K. [Biotechnical Faculty, Department of Biology, University of Ljubljana, Jamnikarjeva 101, SI-1000 Ljubljana (Slovenia); Jeromel, L. [Jožef Stefan Institute, Jamova 39, SI-1000 Ljubljana (Slovenia); Ogrinc Potočnik, N. [Jožef Stefan Institute, Jamova 39, SI-1000 Ljubljana (Slovenia); FOM-Institute AMOLF, Science Park 104, 1098 XG Amsterdam (Netherlands); Pongrac, P. [Biotechnical Faculty, Department of Biology, University of Ljubljana, Jamnikarjeva 101, SI-1000 Ljubljana (Slovenia); Department of Plant Physiology, University of Bayreuth, Universitätstr. 30, 95447 Bayreuth (Germany); Drobne, D.; Pipan Tkalec, Ž.; Novak, S.; Kos, M.; Koren, Š.; Regvar, M. [Biotechnical Faculty, Department of Biology, University of Ljubljana, Jamnikarjeva 101, SI-1000 Ljubljana (Slovenia); Pelicon, P. [Jožef Stefan Institute, Jamova 39, SI-1000 Ljubljana (Slovenia)

    2015-04-01

    The analysis of biological samples in frozen-hydrated state with micro-PIXE technique at Jožef Stefan Institute (JSI) nuclear microprobe has matured to a point that enables us to measure and examine frozen tissue samples routinely as a standard research method. Cryotome-cut slice of frozen-hydrated biological sample is mounted between two thin foils and positioned on the sample holder. The temperature of the cold stage in the measuring chamber is kept below 130 K throughout the insertion of the samples and the proton beam exposure. Matrix composition of frozen-hydrated tissue is consisted mostly of ice. Sample deterioration during proton beam exposure is monitored during the experiment, as both Elastic Backscattering Spectrometry (EBS) and Scanning Transmission Ion Microscopy (STIM) in on–off axis geometry are recorded together with the events in two PIXE detectors and backscattered ions from the chopper in a single list-mode file. The aim of this experiment was to determine differences and similarities between two kinds of biological sample preparation techniques for micro-PIXE analysis, namely freeze-drying and frozen-hydrated sample preparation in order to evaluate the improvements in the elemental localisation of the latter technique if any. In the presented work, a standard micro-PIXE configuration for tissue mapping at JSI was used with five detection systems operating in parallel, with proton beam cross section of 1.0 × 1.0 μm{sup 2} and a beam current of 100 pA. The comparison of the resulting elemental distributions measured at the biological tissue prepared in the frozen-hydrated and in the freeze-dried state revealed differences in elemental distribution of particular elements at the cellular level due to the morphology alteration in particular tissue compartments induced either by water removal in the lyophilisation process or by unsatisfactory preparation of samples for cutting and mounting during the shock-freezing phase of sample preparation.

  6. PROSPECT improves cis-acting regulatory element prediction by integrating expression profile data with consensus pattern searches

    Science.gov (United States)

    Fujibuchi, Wataru; Anderson, John S. J.; Landsman, David

    2001-01-01

    Consensus pattern and matrix-based searches designed to predict cis-acting transcriptional regulatory sequences have historically been subject to large numbers of false positives. We sought to decrease false positives by incorporating expression profile data into a consensus pattern-based search method. We have systematically analyzed the expression phenotypes of over 6000 yeast genes, across 121 expression profile experiments, and correlated them with the distribution of 14 known regulatory elements over sequences upstream of the genes. Our method is based on a metric we term probabilistic element assessment (PEA), which is a ranking of potential sites based on sequence similarity in the upstream regions of genes with similar expression phenotypes. For eight of the 14 known elements that we examined, our method had a much higher selectivity than a naïve consensus pattern search. Based on our analysis, we have developed a web-based tool called PROSPECT, which allows consensus pattern-based searching of gene clusters obtained from microarray data. PMID:11574681

  7. Theoretical analysis of the temperature changes and resultant loss of fuel integrity in the IEA-R1 research reactor fuel elements following a loss of coalant accident

    International Nuclear Information System (INIS)

    Garone, J.G.M.

    1983-01-01

    The IEA-R1 core following a loss of coolant accident (LOCA) is analysed. THe AIRLOCA code was used to calculate fuel temperatures, heat generation due to fission product decay and convective and radiative heat transfer from the fuel elements to the surrounding air both during and following the loss of coolant. The influence of certain critical parameters, such as log time, specific power was studied in detail. Representative results are presented and suggestions made to ensure that fuel integrity is maintained following a LOCA. (Author) [pt

  8. Performance of an optical encoder based on a nondiffractive beam implemented with a specific photodetection integrated circuit and a diffractive optical element.

    Science.gov (United States)

    Quintián, Fernando Perez; Calarco, Nicolás; Lutenberg, Ariel; Lipovetzky, José

    2015-09-01

    In this paper, we study the incremental signal produced by an optical encoder based on a nondiffractive beam (NDB). The NDB is generated by means of a diffractive optical element (DOE). The detection system is composed by an application specific integrated circuit (ASIC) sensor. The sensor consists of an array of eight concentric annular photodiodes, each one provided with a programmable gain amplifier. In this way, the system is able to synthesize a nonuniform detectivity. The contrast, amplitude, and harmonic content of the sinusoidal output signal are analyzed. The influence of the cross talk among the annular photodiodes is placed in evidence through the dependence of the signal contrast on the wavelength.

  9. Is emergency management an integrated element of business continuity management? A case study with security professionals in Western Australia.

    Science.gov (United States)

    Frohde, Kenny; Brooks, David J

    Emergency management (EM) and business continuity management (BCM) frameworks incorporate various strategic and operational measures. Defined within a number of national and international standards and guidelines, such concepts may be integrated within one another to provide increased resilience to disruptive events. Nevertheless, there is a degree of dispute regarding concept integration among security and EM professionals and bodies of knowledge. In line with cognitive psychology exemplar-based concepts, such disputes may be associated with a lack of precision in communality in the approach to EM and BCM. This paper presents a two-stage study, where stage 1 critiqued national and international literature and stage 2 applied semi-structured interviews with security managers in Western Australia. Findings indicate the existence of contradictory views on EM and its integration within BCM. As such, this study concludes that EM is considered a vital component of BCM by the majority of security managers. However, there is broader dispute regarding its degree of integration. Understanding the underpinnings of such disputes will aid in raising the standards and application of professionalism within security, EM and BCM domains, supporting clarification and definition of professional boundaries.

  10. A combined finite element-boundary integral formulation for solution of two-dimensional scattering problems via CGFFT. [Conjugate Gradient Fast Fourier Transformation

    Science.gov (United States)

    Collins, Jeffery D.; Volakis, John L.; Jin, Jian-Ming

    1990-01-01

    A new technique is presented for computing the scattering by 2-D structures of arbitrary composition. The proposed solution approach combines the usual finite element method with the boundary-integral equation to formulate a discrete system. This is subsequently solved via the conjugate gradient (CG) algorithm. A particular characteristic of the method is the use of rectangular boundaries to enclose the scatterer. Several of the resulting boundary integrals are therefore convolutions and may be evaluated via the fast Fourier transform (FFT) in the implementation of the CG algorithm. The solution approach offers the principal advantage of having O(N) memory demand and employs a 1-D FFT versus a 2-D FFT as required with a traditional implementation of the CGFFT algorithm. The speed of the proposed solution method is compared with that of the traditional CGFFT algorithm, and results for rectangular bodies are given and shown to be in excellent agreement with the moment method.

  11. Contribution to the center and integrability problems in planar vector fields

    OpenAIRE

    Santallusia Esvert, Xavier

    2017-01-01

    Aquesta tesi consta d'un primer capítol introductori, set capítols amb diferents resultats i una bibliografia. El primer capítol conté la definició i els resultats previs necessaris per abordar la resta de la memòria. El capítol 2 i 3 estan molt relacionats. En el primer es descriu un mètode alternatiu per al còmput de les constants de Poincaré--Liapunov. A diferència de mètodes anteriors, el mètode presentat no requereix el càlcul d'integrals i d'ona de forma explícita les constants de P...

  12. Integrative study of the behavior of transuranic elements in the marine environment. Progress report, June 1, 1982-May 31, 1983

    International Nuclear Information System (INIS)

    Choppin, G.R.; Morse, J.W.

    1983-01-01

    The adsorption of actinides from marine solutions into sediments was studied to model the distribution and speciation of transuranic elements in the marine environment. The basic plan involves measuring the complexity and hydrolysis constants of actinides in oxidation states III to VI and studying a limited number of common sediment components to determine which factors determine the partitioning of actinides among these components. Individual sediment components then will be combined in synthetic sediments of increasing complexity and the distributions studied between these sediments and solutions

  13. Application of Linear Viscoelastic Properties in Semianalytical Finite Element Method with Recursive Time Integration to Analyze Asphalt Pavement Structure

    Directory of Open Access Journals (Sweden)

    Pengfei Liu

    2018-01-01

    Full Text Available Traditionally, asphalt pavements are considered as linear elastic materials in finite element (FE method to save computational time for engineering design. However, asphalt mixture exhibits linear viscoelasticity at small strain and low temperature. Therefore, the results derived from the elastic analysis will inevitably lead to discrepancies from reality. Currently, several FE programs have already adopted viscoelasticity, but the high hardware demands and long execution times render them suitable primarily for research purposes. Semianalytical finite element method (SAFEM was proposed to solve the abovementioned problem. The SAFEM is a three-dimensional FE algorithm that only requires a two-dimensional mesh by incorporating the Fourier series in the third dimension, which can significantly reduce the computational time. This paper describes the development of SAFEM to capture the viscoelastic property of asphalt pavements by using a recursive formulation. The formulation is verified by comparison with the commercial FE software ABAQUS. An application example is presented for simulations of creep deformation of the asphalt pavement. The investigation shows that the SAFEM is an efficient tool for pavement engineers to fast and reliably predict asphalt pavement responses; furthermore, the SAFEM provides a flexible, robust platform for the future development in the numerical simulation of asphalt pavements.

  14. Metrological certification of systems to monitor the seal integrity of fuel-element cladding based on exposed fuel in sodium-cooled fast reactors

    International Nuclear Information System (INIS)

    Eliseev, A.V.; Filonov, V.S.; Ushakov, V.M.; Belov, S.P.; Pedyash, B.V.; Zemtsev, B.V.; Skorikov, N.V.

    1992-01-01

    In sodium-cooled fast reactors, the clad monitoring system for seal integrity of the fuel element cladding is practically the only source of operator information on the serviceability of fuel elements in the core. The monitoring system can be used as the basis for critical decisions whether the reactor must be shut down of whether operation can continue, but only if the meterologically provided measurements are reliable. This article describes a method developed for certifying working rods on the basis of the domestic standard. The method includes a combined irradiation of the sample and the rod to be certified in an arbitrary field of a plutonium-beryllium neutron source with an output rate greater than 10 8 sec -1 , which is mounted in a paraffin moderator. The positive results of the metrological certification of the system to monitor cladding seal integrity leads the authors to recommend this method for other current and planned sodium-cooled fast reactors. 6 refs., 2 tabs

  15. Linking an Integrative Behavior Model to Elements of Environmental Campaigns: An Analysis of Face-to-Face Communication and Posters against Littering

    Directory of Open Access Journals (Sweden)

    Ralph Hansmann

    2015-05-01

    Full Text Available Diverse elements of anti-littering campaigns may be effective at addressing different causes of littering. Therefore, a complementary approach combining various elements is needed to ensure the behavioral effectiveness of corresponding campaigns. The present study investigates personal, problem-centered face-to-face conversations compared to three different types of anti-littering posters (witty, authoritarian, environmentally oriented. In total, N = 147 persons participated in the questionnaire-based survey. Pictures of the three anti-littering posters were presented to all respondents, but only 82 of them additionally took part in problem-centered face-to-face conversations. Participants of the latter condition liked the conversations significantly more and judged them more effective for reducing littering than each of the three posters. Intentions for future behavior also improved more in the condition with face-to-face communications than in the reference condition in which only the anti-littering posters were presented. Regarding the posters, it was found that the witty and the environmentally-oriented poster were liked more and judged to be more effective by the respondents than the authoritarian poster. Findings are discussed in relation to the design of campaigns, which combine elements with reference to an integrative behavior model covering a broad range of factors, including processes of justifications, habit formation and reactance.

  16. Integration of fuzzy theory into Kano model for classification of service quality elements: A case study in a machinery industry of China

    Directory of Open Access Journals (Sweden)

    Qingliang Meng

    2015-11-01

    Full Text Available Purpose: The purpose of study is to meet customer requirements and improve customer satisfaction that aims to classify customer requirements more effectively. And the classification is focused on the customer psychology. Design/methodology/approach: In this study, considering the advantages of Kano model in taking into account both customer’s consuming psychology and motivation, and combining with fuzzy theory which is effective to cope with uncertainty and ambiguity, a Kano model based on fuzzy theory is proposed. In view of the strong subjectivity of traditional Kano questionnaires, a fuzzy Kano questionnaire to classify the service quality elements more objectively is proposed. Furthermore, this study will also develop a mathematical calculation performance according to the quality classification of fuzzy Kano model. It’s more objective than traditional Kano model to realize the service quality elements classification. With this method, the accurate mentality can be fully reasonable reflected in some unknown circumstances. Finally, an empirical study in Xuzhou Construction Machinery Group Co., Ltd, the largest manufacturing industry in China, is showed to testify its feasibility and validity. Findings: The calculation results indicate that the proposed model has good performance in classifying customer requirements. With this method, the accurate mentality can be fully reasonable reflected in unknown circumstances and it is more objective than traditional Kano model to classify the service quality elements. Originality/value: This study provides a method to integrate fuzzy theory and Kano model, and develops a mathematical calculation performance according to the quality classification of fuzzy Kano model.

  17. The fractionation and geochemical characteristics of rare earth elements measured in ambient size-resolved PM in an integrated iron and steelmaking industry zone.

    Science.gov (United States)

    Dai, Qili; Li, Liwei; Yang, Jiamei; Liu, Baoshuang; Bi, Xiaohui; Wu, Jianhui; Zhang, YuFen; Yao, Lin; Feng, Yinchang

    2016-09-01

    Improved understanding of the fractionation and geochemical characteristic of rare earth elements (REEs) from steel plant emissions is important due to the unclear atmospheric signature of these elements and their adverse impact on human health and the environment. In this study, ambient particulate matter of different sizes was collected from one site in an integrated iron and steelmaking industrial zone (HG) and one urban background site with no direct industrial emissions (ZWY) during a 1-year sampling campaign in China. The total concentrations of REEs for TSP, PM10, and PM2.5 were 27.248, 14.989, 3.542 ng/m(3) in HG and 6.326, 5.274, 1.731 ng/m(3), respectively, in ZWY, which revealed the local influence of the steelmaking activities to the air quality. With respect to ZWY, the REEs in HG site are obviously fractionated in the coarser fraction, and LREEs account for more than 80 % of the total REE burden in all of the samples. Additionally, the REEs in HG and ZWY show a homogeneous trend with successively increased LREE/HREE ratios from the coarse particles to the fine particles. In our samples, La, Ce, Nd, and Sm are the most enriched rare earth elements, especially in the HG site. Moreover, ternary diagrams of LaCeSm indicate that the REEs in HG are potentially contributed by steelworks, carrier vehicles, coal combustion, and road dust re-suspension.

  18. Towards an integrated numerical simulator for crack-seal vein microstructure: Coupling phase-field with the Discrete Element Method

    Science.gov (United States)

    Virgo, Simon; Ankit, Kumar; Nestler, Britta; Urai, Janos L.

    2016-04-01

    Crack-seal veins form in a complex interplay of coupled thermal, hydraulic, mechanical and chemical processes. Their formation and cyclic growth involves brittle fracturing and dilatancy, phases of increased fluid flow and the growth of crystals that fill the voids and reestablish the mechanical strength. Existing numerical models of vein formation focus on selected aspects of the coupled process. Until today, no model exists that is able to use a realistic representation of the fracturing AND sealing processes, simultaneously. To address this challenge, we propose the bidirectional coupling of two numerical methods that have proven themselves as very powerful to model the fundamental processes acting in crack-seal systems: Phase-field and the Discrete Element Method (DEM). The phase-field Method was recently successfully extended to model the precipitation of quartz crystals from an aqueous solution and applied to model the sealing of a vein over multiple opening events (Ankit et al., 2013; Ankit et al., 2015a; Ankit et al., 2015b). The advantage over former, purely kinematic approaches is that in phase-field, the crystal growth is modeled based on thermodynamic and kinetic principles. Different driving forces for microstructure evolution, such as chemical bulk free energy, interfacial energy, elastic strain energy and different transport processes, such as mass diffusion and advection, can be coupled and the effect on the evolution process can be studied in 3D. The Discrete Element Method was already used in several studies to model the fracturing of rocks and the incremental growth of veins by repeated fracturing (Virgo et al., 2013; Virgo et al., 2014). Materials in DEM are represented by volumes of packed spherical particles and the response to the material to stress is modeled by interaction of the particles with their nearest neighbours. For rocks, in 3D, the method provides a realistic brittle failure behaviour. Exchange Routines are being developed that

  19. Simplified 3D Finite Element Analysis of Linear Inductor Motor for Integrated Magnetic Suspension/Propulsion Applications

    Energy Technology Data Exchange (ETDEWEB)

    Jeong, Sang Sub; Jang Seok Myeong [Chungnam National University(Korea)

    2000-06-01

    The 4-pole linear homopolar synchronous motor (LHSM), so called linear inductor motor, is composed of the figure-of-eight shaped 3-phase armature windings, DC field windings, and the segmented secondary with the transverse bar track. To reduce the calculation time, the simplified 3D finite element model with equivalent reluctance and/or permanent magnet is presented. To obtain a clear understanding, propriety and usefulness of the developed mode., we compare with the results of simplified 3D FEA and test. Consequently, the results of simplified and 3D FEM analysis are nearly identical, but much larger than that of static test at d-axis armature excitation. Therefore the improved FEA model, such as full model with half slot, is needed for the precise analysis. (author). refs., figs., tabs.

  20. Integrating the fish embryo toxicity test as triad element for sediment toxicity assessment based on the water framework directive approach

    Energy Technology Data Exchange (ETDEWEB)

    Bartzke, Mariana [Dept. Aquatic Ecotoxicology, Goethe Univ. Frankfurt am Main (Germany); Gobio GmbH, Aarbergen/Kettenbach (Germany); Dept. Bioanalytical Ecotoxicology, Helmholtz Centre for Environmental Research, UFZ, Leipzig (Germany); Delov, Vera [Dept. Aquatic Ecotoxicology, Goethe Univ. Frankfurt am Main (Germany); Gobio GmbH, Aarbergen/Kettenbach (Germany); Ecotoxicology, Fraunhofer Inst. for Molecular Biology and Applied Ecology IME, Aachen (Germany); Stahlschmidt-Allner, Petra; Allner, Bernhard [Gobio GmbH, Aarbergen/Kettenbach (Germany); Oehlmann, Joerg [Dept. Aquatic Ecotoxicology, Goethe Univ. Frankfurt am Main (Germany)

    2010-04-15

    Purpose: The objective of this study was to complement analyses according to the European Union Water Framework Directive (WFD) with a sediment toxicity analysis as part of an integrated river assessment. To this end, Hessian water courses were analyzed using the sediment quality triad concept according to Chapman with chemical analyses, in situ effect evaluations, and ecotoxicological assessments. For the ecotoxicological assessment (fish embryo toxicity test with Danio rerio), a new evaluation scheme was developed, the fish teratogenicity index (FTI), that allows for a classification of sediments into ecological quality classes compliant to the WFD. Materials and methods sediment and macrozoobenthos samples were taken from tributaries of the rivers Fulda and Lahn. Sediments were characterized regarding particle size, carbon, heavy metals, and polyaromatic hydrocarbon content. Macroinvertebrate samples were taken via multi-habitat sampling. The fish embryo toxicity test with D. rerio was conducted as a contact assay on the basis of DIN 38415-6. Results and discussion The integrated assessment indicated a significant influence of heavy metals and carbon content on macroinvertebrate communities. The bioaccessibility of sediment pollutants were clearly demonstrated by the FTI, which showed a wide range of adverse effects. A significant linear relationship between metals and the FTI was detected. However, there was no statistically significant evidence that macroinvertebrate communities were affected by the hydromorphological quality clements at the sampling sites. Conclusions The new scheme for the assessment of fish embryo toxicity test was successfully applied. The results suggest that sediment compounds impact macroinvertebrate communities and early development of fish. It demonstrates that the quality of sediments should be evaluated on a routine basis as part of an integrated river assessment. (orig.)

  1. Integrated non-destructive assessment of relevant structural elements of an Italian heritage site: the Carthusian monastery of Trisulti

    International Nuclear Information System (INIS)

    Rainieri, C; Marra, A; Gargaro, D; Fabbrocino, G; Rainieri, G M; Pepe, M

    2015-01-01

    The analysis of historical structures in need of preservation and restoration interventions is a very complex task due to the large uncertainties in the characterization of structural properties and detailing in view of the structural response. Moreover, the predictive performance of numerical analyses and simulations depend on the availability of information about the constructional properties of the architectural complex, crack patterns and active degradation phenomena. In particular, local changes in material properties or damage due to past events (such as earthquakes) can affect individual structural elements. They can be hardly detected as a result of the maintenance interventions carried out over the centuries and the possibility to carry out limited or even no destructive investigations due to the historical relevance of the structure. Thus, non-destructive investigations play a fundamental role in the assessment of historical structures minimizing, at the same time, the invasiveness of interventions. The present paper deals with an explanatory case study concerning the structural investigations carried out in view of the seismic assessment of an Italian historical monument, the Carthusian monastery of Trisulti in Collepardo, erected in 1204 under Pope Innocenzo HI. The relevance of the case study is due to the application, in combination, of different NDT methods, such as sonic tests, and active and passive infrared thermography, in order to characterize relevant masonry elements. Moreover, an advanced system for the in-situ nondestructive vibration-based estimation of the tensile loads in ancient tie-rods is described and the main results obtained from its application for the characterization of the tie-rods of the cloister are presented. (paper)

  2. Design of a novel integration-deficient lentivector technology that incorporates genetic and posttranslational elements to target human dendritic cells.

    Science.gov (United States)

    Tareen, Semih U; Kelley-Clarke, Brenna; Nicolai, Christopher J; Cassiano, Linda A; Nelson, Lisa T; Slough, Megan M; Vin, Chintan D; Odegard, Jared M; Sloan, Derek D; Van Hoeven, Neal; Allen, James M; Dubensky, Thomas W; Robbins, Scott H

    2014-03-01

    As sentinels of the immune system, dendritic cells (DCs) play an essential role in regulating cellular immune responses. One of the main challenges of developing DC-targeted therapies includes the delivery of antigen to DCs in order to promote the activation of antigen-specific effector CD8 T cells. With the goal of creating antigen-directed immunotherapeutics that can be safely administered directly to patients, Immune Design has developed a platform of novel integration-deficient lentiviral vectors that target and deliver antigen-encoding nucleic acids to human DCs. This platform, termed ID-VP02, utilizes a novel genetic variant of a Sindbis virus envelope glycoprotein with posttranslational carbohydrate modifications in combination with Vpx, a SIVmac viral accessory protein, to achieve efficient targeting and transduction of human DCs. In addition, ID-VP02 incorporates safety features in its design that include two redundant mechanisms to render ID-VP02 integration-deficient. Here, we describe the characteristics that allow ID-VP02 to specifically transduce human DCs, and the advances that ID-VP02 brings to conventional third-generation lentiviral vector design as well as demonstrate upstream production yields that will enable manufacturing feasibility studies to be conducted.

  3. A new mosaic integrative and conjugative element from Streptococcus agalactiae carrying resistance genes for chloramphenicol (catQ) and macrolides [mef(I) and erm(TR)].

    Science.gov (United States)

    Morici, Eleonora; Simoni, Serena; Brenciani, Andrea; Giovanetti, Eleonora; Varaldo, Pietro E; Mingoia, Marina

    2017-01-01

    To investigate the genetic basis of catQ-mediated chloramphenicol resistance in Streptococcus agalactiae. Two clinical strains of catQ-positive chloramphenicol-resistant S. agalactiae (Sag236 and Sag403) were recently isolated, typed (MLST, PFGE pulsotypes, capsular types) and their antibiotic resistances investigated by phenotypic and genotypic approaches. Several molecular methods (PCR mapping, restriction assays, Southern blotting, sequencing and sequence analysis, conjugal transfer assays) were used to determine the genetic context of catQ and characterize a genetic element detected in the isolates. Sag236 and Sag403 shared the same ST (ST19), but exhibited a different capsular type (III and V, respectively) and pulsotype. Both harboured the macrolide resistance genes mef(I) and erm(TR) and the tetracycline resistance gene tet(M). Accordingly, they were resistant to chloramphenicol, erythromycin and tetracycline. catQ and mef(I) were associated in an IQ module that was indistinguishable in Sag236 and Sag403. In mating assays, chloramphenicol and erythromycin resistance proved transferable, at low frequency, only from Sag236. Transconjugants carried not only catQ and mef(I), but also erm(TR), suggesting a linkage of the three resistance genes in a mobile element, which, though seemingly non-mobile, was also detected in Sag403. The new element (designated ICESag236, ∼110 kb) results from recombination of two integrative and conjugative elements (ICEs) originally described in different streptococcal species: S. agalactiae ICESagTR7, carrying erm(TR); and Streptococcus pneumoniae ICESpn529IQ, carrying the prototype IQ module. These findings strengthen the notion that widespread streptococcal ICEs may form mosaics that enhance their diversity and spread, broaden their host range and carry new cargo genes. © The Author 2016. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions

  4. Live-Load Testing Application Using a Wireless Sensor System and Finite-Element Model Analysis of an Integral Abutment Concrete Girder Bridge

    Directory of Open Access Journals (Sweden)

    Robert W. Fausett

    2014-01-01

    Full Text Available As part of an investigation on the performance of integral abutment bridges, a single-span, integral abutment, prestressed concrete girder bridge near Perry, Utah was instrumented for live-load testing. The live-load test included driving trucks at 2.24 m/s (5 mph along predetermined load paths and measuring the corresponding strain and deflection. The measured data was used to validate a finite-element model (FEM of the bridge. The model showed that the integral abutments were behaving as 94% of a fixed-fixed support. Live-load distribution factors were obtained using this validated model and compared to those calculated in accordance to recommended procedures provided in the AASHTO LRFD Bridge Design Specifications (2010. The results indicated that if the bridge was considered simply supported, the AASHTO LRFD Specification distribution factors were conservative (in comparison to the FEM results. These conservative distribution factors, along with the initial simply supported design assumption resulted in a very conservative bridge design. In addition, a parametric study was conducted by modifying various bridge properties of the validated bridge model, one at a time, in order to investigate the influence that individual changes in span length, deck thickness, edge distance, skew, and fixity had on live-load distribution. The results showed that the bridge properties with the largest influence on bridge live-load distribution were fixity, skew, and changes in edge distance.

  5. Energy-Integrating Master Plan for the City of Atlantic City, New Jersey: energy conservation element. Volume 3

    Energy Technology Data Exchange (ETDEWEB)

    1978-11-01

    The Master Plan describes a coordinated energy-conservation effort for the City, the effective application and ultimate success of which depend primarily on the active involvement of the City government and its functional departments. Following an introductory section, Section XXI, Community Energy Determinants, describes the natural and man-made environment, growth and energy profiles, and the institutional environment. Additional sections are entitled: Energy-Conservation Options (passive energy options and active energy-conservation options); Energy Integration; Community Energy Management; Energy-Conservation Implementation Plan; and an appendix containing an energy-related glossary, a directory to various sources of information on energy conservation, various technical documents, a copy of the National Energy Act, and a bibliography. (MCW)

  6. Conceptual Frameworks for the Workplace Change Adoption Process: Elements Integration from Decision Making and Learning Cycle Process.

    Science.gov (United States)

    Radin Umar, Radin Zaid; Sommerich, Carolyn M; Lavender, Steve A; Sanders, Elizabeth; Evans, Kevin D

    2018-05-14

    Sound workplace ergonomics and safety-related interventions may be resisted by employees, and this may be detrimental to multiple stakeholders. Understanding fundamental aspects of decision making, behavioral change, and learning cycles may provide insights into pathways influencing employees' acceptance of interventions. This manuscript reviews published literature on thinking processes and other topics relevant to decision making and incorporates the findings into two new conceptual frameworks of the workplace change adoption process. Such frameworks are useful for thinking about adoption in different ways and testing changes to traditional intervention implementation processes. Moving forward, it is recommended that future research focuses on systematic exploration of implementation process activities that integrate principles from the research literature on sensemaking, decision making, and learning processes. Such exploration may provide the groundwork for development of specific implementation strategies that are theoretically grounded and provide a revised understanding of how successful intervention adoption processes work.

  7. Customized surgical template fabrication under biomechanical consideration by integrating CBCT image, CAD system and finite element analysis.

    Science.gov (United States)

    Yu, Jian-Hong; Wang, Yu-Tzu; Lin, Chun-Li

    2018-01-30

    This study developed a customized surgical template under mechanical consideration for molar intrusion. Two finite element (FE) models were analyzed for the primary stability under 100 gf traction forces with one mini-screw inserted at the buccal side in horizontal and another in palatal side with two optional positions at 60° (P60) or 15° (P15) angles with inclination toward the molar occlusal surface. The surgical template was generated using rapid prototyping (RP) printing for the clinical application based on improved primarily stability model. The surrounding bone strains for models P15 and P60 were far lower than the bone remodeling critical value. Model P60 presented much lower micro-motion in the screw/bone interface and the screw head displacement than those values in model P15. Using FE analysis for biomechanical evaluation and combining with CT image, image superimposed method and CAD technique can fabricate accuracy/security customized surgical template for mini-screws with better primary stability.

  8. Response and binding elements for ligand-dependent positive transcription factors integrate positive and negative regulation of gene expression

    International Nuclear Information System (INIS)

    Rosenfeld, M.G.; Glass, C.K.; Adler, S.; Crenshaw, E.B. III; He, X.; Lira, S.A.; Elsholtz, H.P.; Mangalam, H.J.; Holloway, J.M.; Nelson, C.; Albert, V.R.; Ingraham, H.A.

    1988-01-01

    Accurate, regulated initiation of mRNA transcription by RNA polymerase II is dependent on the actions of a variety of positive and negative trans-acting factors that bind cis-acting promoter and enhancer elements. These transcription factors may exert their actions in a tissue-specific manner or function under control of plasma membrane or intracellular ligand-dependent receptors. A major goal in the authors' laboratory has been to identify the molecular mechanisms responsible for the serial activation of hormone-encoding genes in the pituitary during development and the positive and negative regulation of their transcription. The anterior pituitary gland contains phenotypically distinct cell types, each of which expresses unique trophic hormones: adrenocorticotropic hormone, thyroid-stimulating hormone, prolactin, growth hormone, and follicle-stimulating hormone/luteinizing hormone. The structurally related prolactin and growth hormone genes are expressed in lactotrophs and somatotrophs, respectively, with their expression virtually limited to the pituitary gland. The reported transient coexpression of these two structurally related neuroendocrine genes raises the possibility that the prolactin and growth hormone genes are developmentally controlled by a common factor(s)

  9. An Integrated Musculoskeletal-Finite-Element Model to Evaluate Effects of Load Carriage on the Tibia During Walking.

    Science.gov (United States)

    Xu, Chun; Silder, Amy; Zhang, Ju; Hughes, Julie; Unnikrishnan, Ginu; Reifman, Jaques; Rakesh, Vineet

    2016-10-01

    Prior studies have assessed the effects of load carriage on the tibia. Here, we expand on these studies and investigate the effects of load carriage on joint reaction forces (JRFs) and the resulting spatiotemporal stress/strain distributions in the tibia. Using full-body motion and ground reaction forces from a female subject, we computed joint and muscle forces during walking for four load carriage conditions. We applied these forces as physiological loading conditions in a finite-element (FE) analysis to compute strain and stress. We derived material properties from computed tomography (CT) images of a sex-, age-, and body mass index-matched subject using a mesh morphing and mapping algorithm, and used them within the FE model. Compared to walking with no load, the knee JRFs were the most sensitive to load carriage, increasing by as much as 26.2% when carrying a 30% of body weight (BW) load (ankle: 16.4% and hip: 19.0%). Moreover, our model revealed disproportionate increases in internal JRFs with increases in load carriage, suggesting a coordinated adjustment in the musculature functions in the lower extremity. FE results reflected the complex effects of spatially varying material properties distribution and muscular engagement on tibial biomechanics during walking. We observed high stresses on the anterior crest and the medial surface of the tibia at pushoff, whereas high cumulative stress during one walking cycle was more prominent in the medioposterior aspect of the tibia. Our findings reinforce the need to include: (1) physiologically accurate loading conditions when modeling healthy subjects undergoing short-term exercise training and (2) the duration of stress exposure when evaluating stress-fracture injury risk. As a fundamental step toward understanding the instantaneous effect of external loading, our study presents a means to assess the relationship between load carriage and bone biomechanics.

  10. Petroleum system elements within the Late Cretaceous and Early Paleogene sediments of Nigeria's inland basins: An integrated sequence stratigraphic approach

    Science.gov (United States)

    Dim, Chidozie Izuchukwu Princeton; Onuoha, K. Mosto; Okeugo, Chukwudike Gabriel; Ozumba, Bertram Maduka

    2017-06-01

    Sequence stratigraphic studies have been carried out using subsurface well and 2D seismic data in the Late Cretaceous and Early Paleogene sediments of Anambra and proximal onshore section of Niger Delta Basin in the Southeastern Nigeria. The aim was to establish the stratigraphic framework for better understanding of the reservoir, source and seal rock presence and distribution in the basin. Thirteen stratigraphic bounding surfaces (consisting of six maximum flooding surfaces - MFSs and seven sequence boundaries - SBs) were recognized and calibrated using a newly modified chronostratigraphic chart. Stratigraphic surfaces were matched with corresponding foraminiferal and palynological biozones, aiding correlation across wells in this study. Well log sequence stratigraphic correlation reveals that stratal packages within the basin are segmented into six depositional sequences occurring from Late Cretaceous to Early Paleogene age. Generated gross depositional environment maps at various MFSs show that sediment packages deposited within shelfal to deep marine settings, reflect continuous rise and fall of sea levels within a regressive cycle. Each of these sequences consist of three system tracts (lowstand system tract - LST, transgressive system tract - TST and highstand system tract - HST) that are associated with mainly progradational and retrogradational sediment stacking patterns. Well correlation reveals that the sand and shale units of the LSTs, HSTs and TSTs, that constitute the reservoir and source/seal packages respectively are laterally continuous and thicken basinwards, due to structural influences. Result from interpretation of seismic section reveals the presence of hanging wall, footwall, horst block and collapsed crest structures. These structural features generally aid migration and offer entrapment mechanism for hydrocarbon accumulation. The combination of these reservoirs, sources, seals and trap elements form a good petroleum system that is viable

  11. ECOLOGICAL THERAPY AS CORRECTIONAL AND PEDAGOGICAL ELEMENT OF INTEGRATED APPROACH IN THE TREATMENT OF LOGONEUROSIS AMONG PRESCHOOL CHILDREN

    Directory of Open Access Journals (Sweden)

    I. V. Kalashnikova

    2016-01-01

    Full Text Available . The aims of the publication are: to analyse domestic experience of education and training of preschool children with logoneurosis; to designate the causes and displays of this disease; to define the problems arising through organization of correctional work in preschool institution taking into account modern requirements of the Russian legislation and climatic features of regions; to present a possible version of the solution of these problems.Methods. The methods of theoretical analysis and generalization of scientific, methodical publications, and legislative base on a problem of correctional work on stuttering among preschool children are used.Results and scientific novelty. The authors’ program of additional education with the correctional elements «Ecotherapy for Children at the age of 5–7 years with Logoneurosis» developed by the staff of the Ecotherapy Laboratory of the Polar Alpine Botanical Garden – Institute named after N. A. Avrorin is described in the publication. The program complies with the modern requirements of Federal State Educational Standard of preschool education and is focused on tutors and speech language therapists of correctional groups and logocentres. In the course of mastering the program, a child by means of a game at once joins in search-investigative activity in the field of biology and ecology with visualization of an ultimate goal and obligatory practical material realization of results of work. From the point of view of medical expediency, the program has included the special breathing and relaxation exercises which are picked up for the lesson topic. The efficiency of a combination in correctional pedagogics of standard logopedic methods and the practise with nonconventional methods of art-, garden-, and animal-assisted therapy is confirmed. Special relevance of the proposed techniques and methods in the conditions of the Polar region (the region, wherein during the period of an exit from polar night

  12. Element Specific Versus Integral Structural and Magnetic Properties of Co:ZnO and Gd:GaN Probed with Hard X-ray Absorption Spectroscopy

    Directory of Open Access Journals (Sweden)

    Andreas Ney

    2010-06-01

    Full Text Available Dilute magnetic semiconductors (DMS are envisioned as sources of spin-polarized carriers for future semiconductor devices which simultaneously utilize spin and charge of the carriers. The hope of discovering a DMS with ferromagnetic order up to room temperature still motivates research on suitable DMS materials. Two candidate wide-band gap DMS are Gd:GaN and Co:ZnO. We have used hard X-ray absorption spectroscopy (XAS and in particular X-ray linear dichroism (XLD and X-ray magnetic circular dichroism (XMCD to study both DMS materials with element specificity and compare these findings with results from integral SQUID magnetometry as well as electron paramagnetic resonance (EPR.

  13. [Three-dimensional finite element analysis on mechanical behavior of the bone remodeling and bone integration between the bone-implant interface after hip replacement].

    Science.gov (United States)

    Li, Yong-Jiang; Zhang, Li-Cheng; Zhang, Mei-Chao; Yang, Guo-Jing; Lin, Rui-Xin; Cai, Chun-Yuan; Zhong, Shi-Zhen

    2014-04-01

    To discuss the primary stability of the fixed interface between the cementless prosthesis and femur, and its influence on bone ingrowth and secondary stability under the roughened surface and press fit of different prostheses by finite element analysis. :A three-dimensional finite element module of total hip arthroplasty (THA) was developed with Mimics software. There was a collection of data when simulating hip arthroplasty. The frictional coefficient between the fixed interface was 0,0.15,0.40 and 1.00 representing the roughness of prosthesis surface. The press fit was 0, 0.01,0.05 and 0.10 mm according to the operation. The Vion Mises stress distribution and the contact pressure,friction stress and relative sliding displacement between the interface were analysed and compared when simulating the maneuver of climbing stairs. At a fixed press fit of 0.05 mm,the contact pressure between the interface was 230 , 231, 222 and 275 MN under four different frictional coefficient (0,0. 15,0.40 and 1.00) with little change; the relative sliding displacement was 0.529, 0.129, 0.107 and 0.087 mm with a consistent and obvious decline. As the fixed frictional coefficient was 0.40,the contact pressure between the interface were 56.0,67.7 ,60.4 and 49.6 MN under four different press fit (0, 0.01, 0.05 and 0.10 mm) with a reduction; the relative sliding displacement was 0.064,0.062,0.043 and 0.042 mm with an obvious decline, and there was a maximal friction stress when press fit of 0.01 mm. There is a dynamic process of the bone remodeling and bone integration between the interface after hip replacement, determining the long-term outcome. The interface clearance and the frictional coefficient are the key factors of the bone integration.

  14. Disruption of a Transcriptional Repressor by an Insertion Sequence Element Integration Leads to Activation of a Novel Silent Cellobiose Transporter in Lactococcus lactis MG1363.

    Science.gov (United States)

    Solopova, Ana; Kok, Jan; Kuipers, Oscar P

    2017-12-01

    Lactococcus lactis subsp. cremoris strains typically carry many dairy niche-specific adaptations. During adaptation to the milk environment these former plant strains have acquired various pseudogenes and insertion sequence elements indicative of ongoing genome decay and frequent transposition events in their genomes. Here we describe the reactivation of a silenced plant sugar utilization cluster in an L. lactis MG1363 derivative lacking the two main cellobiose transporters, PtcBA-CelB and PtcBAC, upon applying selection pressure to utilize cellobiose. A disruption of the transcriptional repressor gene llmg_1239 by an insertion sequence (IS) element allows expression of the otherwise silent novel cellobiose transporter Llmg_1244 and leads to growth of mutant strains on cellobiose. Llmg_1239 was labeled CclR, for c ellobiose cl uster r epressor. IMPORTANCE Insertion sequences (ISs) play an important role in the evolution of lactococci and other bacteria. They facilitate DNA rearrangements and are responsible for creation of new genetic variants with selective advantages under certain environmental conditions. L. lactis MG1363 possesses 71 copies in a total of 11 different types of IS elements. This study describes yet another example of an IS-mediated adaptive evolution. An integration of IS 981 or IS 905 into a gene coding for a transcriptional repressor led to activation of the repressed gene cluster coding for a plant sugar utilization pathway. The expression of the gene cluster allowed assembly of a novel cellobiose-specific transporter and led to cell growth on cellobiose. Copyright © 2017 American Society for Microbiology.

  15. 'Integration'

    DEFF Research Database (Denmark)

    Olwig, Karen Fog

    2011-01-01

    , while the countries have adopted disparate policies and ideologies, differences in the actual treatment and attitudes towards immigrants and refugees in everyday life are less clear, due to parallel integration programmes based on strong similarities in the welfare systems and in cultural notions...... of equality in the three societies. Finally, it shows that family relations play a central role in immigrants’ and refugees’ establishment of a new life in the receiving societies, even though the welfare society takes on many of the social and economic functions of the family....

  16. Enterobacter cloacae Complex Isolates Harboring blaNMC-A or blaIMI-Type Class A Carbapenemase Genes on Novel Chromosomal Integrative Elements and Plasmids.

    Science.gov (United States)

    Boyd, David A; Mataseje, Laura F; Davidson, Ross; Delport, Johannes A; Fuller, Jeff; Hoang, Linda; Lefebvre, Brigitte; Levett, Paul N; Roscoe, Diane L; Willey, Barbara M; Mulvey, Michael R

    2017-05-01

    Carbapenem-resistant Enterobacter cloacae complex isolates submitted to a reference laboratory from 2010 to 2015 were screened by PCR for seven common carbapenemase gene groups, namely, KPC, NDM, OXA-48, VIM, IMP, GES, and NMC-A/IMI. Nineteen of the submitted isolates (1.7%) were found to harbor Ambler class A bla NMC-A or bla IMI -type carbapenemases. All 19 isolates were resistant to at least one carbapenem but susceptible to aminoglycosides, trimethoprim-sulfamethoxazole, tigecycline, and ciprofloxacin. Most isolates (17/19) gave positive results with the Carba-NP test for phenotypic carbapenemase detection. Isolates were genetically diverse by pulsed-field gel electrophoresis macrorestriction analysis, multilocus sequence typing, and hsp60 gene analysis. The genes were found in various Enterobacter cloacae complex species; however, bla NMC-A was highly associated with Enterobacter ludwigii Whole-genome sequencing and bioinformatics analysis revealed that all NMC-A ( n = 10), IMI-1 ( n = 5), and IMI-9 ( n = 2) producers harbored the carbapenemase gene on EludIMEX-1-like integrative mobile elements (EcloIMEXs) located in the identical chromosomal locus. Two novel genes, bla IMI-5 and bla IMI-6 , were harbored on different IncFII-type plasmids. Enterobacter cloacae complex isolates harboring bla NMC-A/IMI -type carbapenemases are relatively rare in Canada. Though mostly found integrated into the chromosome, some variants are located on plasmids that may enhance their mobility potential. © Crown copyright 2017.

  17. The VanE operon in Enterococcus faecalis N00-410 is found on a putative integrative and conjugative element, Tn6202.

    Science.gov (United States)

    Boyd, D A; Mulvey, M R

    2013-02-01

    To date no complete genetic structure of acquired DNA harbouring a d-Ala-d-Ser operon in an Enterococcus is known. We wished to characterize the acquired DNA harbouring the vanE operon located in the Enterococcus faecalis N00-410 chromosome. Whole genome sequencing of E. faecalis N00-410 was conducted by massively parallel sequencing. Two sequence contigs harbouring the vanE region were linked by PCR and the acquired DNA harbouring the vanE operon was completely characterized. Excision/integration of the region was determined by PCR and transfer attempted by conjugation. The regions flanking the vanE operon were analysed and a total of 42 open reading frames were identified in a region flanked by inverted terminal and direct repeats (Tn6202). Tn6202 could be excised from the chromosome, circularized and the target site rejoined, but transfer could not be demonstrated. The vanE operon was found on the putative integrative and conjugative element Tn6202 in the E. faecalis N00-410 chromosome. This represents the first characterization of acquired DNA harbouring a D-Ala-D-Ser operon.

  18. Hot-Fire Test Results of an Oxygen/RP-2 Multi-Element Oxidizer-Rich Staged-Combustion Integrated Test Article

    Science.gov (United States)

    Hulka, J. R.; Protz, C. S.; Garcia, C. P.; Casiano, M. J.; Parton, J. A.

    2016-01-01

    As part of the Combustion Stability Tool Development project funded by the Air Force Space and Missile Systems Center, the NASA Marshall Space Flight Center was contracted to assemble and hot-fire test a multi-element integrated test article demonstrating combustion characteristics of an oxygen/hydrocarbon propellant oxidizer-rich staged-combustion engine thrust chamber. Such a test article simulates flow through the main injectors of oxygen/kerosene oxidizer-rich staged combustion engines such as the Russian RD-180 or NK-33 engines, or future U.S.-built engine systems such as the Aerojet-Rocketdyne AR-1 engine or the Hydrocarbon Boost program demonstration engine. For the thrust chamber assembly of the test article, several configurations of new main injectors, using relatively conventional gas-centered swirl coaxial injector elements, were designed and fabricated. The design and fabrication of these main injectors are described in a companion paper at this JANNAF meeting. New ablative combustion chambers were fabricated based on hardware previously used at NASA for testing at similar size and pressure. An existing oxygen/RP-1 oxidizer-rich subscale preburner injector from a previous NASA-funded program, along with existing and new inter-connecting hot gas duct hardware, were used to supply the oxidizer-rich combustion products to the oxidizer circuit of the main injector of the thrust chamber. Results from independent hot-fire tests of the preburner injector in a combustion chamber with a sonic throat are described in companion papers at this JANNAF conference. The resulting integrated test article - which includes the preburner, inter-connecting hot gas duct, main injector, and ablative combustion chamber - was assembled at Test Stand 116 at the East Test Area of the NASA Marshall Space Flight Center. The test article was well instrumented with static and dynamic pressure, temperature, and acceleration sensors to allow the collected data to be used for

  19. GLOBULAR CLUSTER ABUNDANCES FROM HIGH-RESOLUTION, INTEGRATED-LIGHT SPECTROSCOPY. IV. THE LARGE MAGELLANIC CLOUD: α, Fe-PEAK, LIGHT, AND HEAVY ELEMENTS

    International Nuclear Information System (INIS)

    Colucci, Janet E.; Bernstein, Rebecca A.; Cameron, Scott A.; McWilliam, Andrew

    2012-01-01

    We present detailed chemical abundances in eight clusters in the Large Magellanic Cloud (LMC). We measure abundances of 22 elements for clusters spanning a range in age of 0.05-12 Gyr, providing a comprehensive picture of the chemical enrichment and star formation history of the LMC. The abundances were obtained from individual absorption lines using a new method for analysis of high-resolution (R ∼ 25,000), integrated-light (IL) spectra of star clusters. This method was developed and presented in Papers I, II, and III of this series. In this paper, we develop an additional IL χ 2 -minimization spectral synthesis technique to facilitate measurement of weak (∼15 mÅ) spectral lines and abundances in low signal-to-noise ratio data (S/N ∼ 30). Additionally, we supplement the IL abundance measurements with detailed abundances that we measure for individual stars in the youngest clusters (age +0.5) and increases with decreasing age, indicating a strong contribution of low-metallicity asymptotic giant branch star ejecta to the interstellar medium throughout the later history of the LMC. We also find a correlation of IL Na and Al abundances with cluster mass in the sense that more massive, older clusters are enriched in the light elements Na and Al with respect to Fe, which implies that these clusters harbor star-to-star abundance variations as is common in the MW. Lower mass, intermediate-age, and young clusters have Na and Al abundances that are lower and more consistent with LMC field stars. Our results can be used to constrain both future chemical evolution models for the LMC and theories of globular cluster formation.

  20. Genome analysis of a clinical isolate of Shewanella sp. uncovered an active hybrid integrative and conjugative element carrying an integron platform inserted in a novel genomic locus.

    Science.gov (United States)

    Parmeciano Di Noto, Gisela; Jara, Eugenio; Iriarte, Andrés; Centrón, Daniela; Quiroga, Cecilia

    2016-08-01

    Shewanella spp. are currently considered to be emerging pathogens that can code for a blaOXA carbapenemase in their chromosome. Complete genome analysis of the clinical isolate Shewanella sp. Sh95 revealed that this strain is a novel species, which shares a lineage with marine isolates. Characterization of its resistome showed that it codes for genes drfA15, qacH and blaOXA-48. We propose that Shewanella sp. Sh95 acts as reservoir of blaOXA-48. Moreover, analysis of mobilome showed that it contains a novel integrative and conjugative element (ICE), named ICESh95. Comparative analysis between the close relatives ICESpuPO1 from Shewanella sp. W3-18-1 and ICE SXTMO10 from Vibrio cholerae showed that ICESh95 encompassed two new regions, a type III restriction modification system and a multidrug resistance integron. The integron platform contained a novel arrangement formed by gene cassettes drfA15 and qacH, and a class C-attC group II intron. Furthermore, insertion of ICESh95 occurred at a unique target site, which correlated with the presence of a different xis/int module. Mobility of ICESh95 was assessed and demonstrated its ability to self-transfer with high efficiency to different species of bacteria. Our results show that ICESh95 is a self-transmissible, mobile element, which can contribute to the dissemination of antimicrobial resistance; this is clearly a threat when natural bacteria from water ecosystems, such as Shewanella, act as vectors in its propagation.

  1. Globular Cluster Abundances from High-resolution, Integrated-light Spectroscopy. IV. The Large Magellanic Cloud: α, Fe-peak, Light, and Heavy Elements

    Science.gov (United States)

    Colucci, Janet E.; Bernstein, Rebecca A.; Cameron, Scott A.; McWilliam, Andrew

    2012-02-01

    We present detailed chemical abundances in eight clusters in the Large Magellanic Cloud (LMC). We measure abundances of 22 elements for clusters spanning a range in age of 0.05-12 Gyr, providing a comprehensive picture of the chemical enrichment and star formation history of the LMC. The abundances were obtained from individual absorption lines using a new method for analysis of high-resolution (R ~ 25,000), integrated-light (IL) spectra of star clusters. This method was developed and presented in Papers I, II, and III of this series. In this paper, we develop an additional IL χ2-minimization spectral synthesis technique to facilitate measurement of weak (~15 mÅ) spectral lines and abundances in low signal-to-noise ratio data (S/N ~ 30). Additionally, we supplement the IL abundance measurements with detailed abundances that we measure for individual stars in the youngest clusters (age +0.5) and increases with decreasing age, indicating a strong contribution of low-metallicity asymptotic giant branch star ejecta to the interstellar medium throughout the later history of the LMC. We also find a correlation of IL Na and Al abundances with cluster mass in the sense that more massive, older clusters are enriched in the light elements Na and Al with respect to Fe, which implies that these clusters harbor star-to-star abundance variations as is common in the MW. Lower mass, intermediate-age, and young clusters have Na and Al abundances that are lower and more consistent with LMC field stars. Our results can be used to constrain both future chemical evolution models for the LMC and theories of globular cluster formation. This paper includes data gathered with the 6.5 m Magellan Telescopes located at Las Campanas Observatory, Chile.

  2. Identification and characterization of new members of the SXT/R391 family of integrative and conjugative elements (ICEs) in Proteus mirabilis.

    Science.gov (United States)

    Bie, Luyao; Wu, Hao; Wang, Xin-Hua; Wang, Mingyu; Xu, Hai

    2017-08-01

    Integrative and conjugative elements (ICEs) are self-transmissible chromosomal mobile elements that play significant roles in the dissemination of antimicrobial resistance genes. Identification of the structures and functions of ICEs, particularly those in pathogens, improves understanding of the dissemination of antimicrobial resistance. This study identified new members of the sulfamethoxazole-trimethoprim (SXT)/R391 family of ICEs that could confer multi-drug resistance in the opportunistic pathogen Proteus mirabilis, characterized their genetic structures, and explored their evolutionary connection with other members of this family of ICEs. Three new members of the SXT/R391 family of ICEs were detected in six of 77 P. mirabilis strains isolated in China: ICEPmiChn2 (one strain), ICEPmiChn3 (one strain) and ICEPmiChn4 (three strains). All three new ICEs harbour antimicrobial resistance genes from diverse origins, suggesting their capability in acquiring foreign genes and serving as important carriers for antimicrobial resistance genes. Structural analysis showed that ICEPmiChn3 is a particularly interesting and unique ICE that has lost core genes involved in conjugation, and could not transfer to other cells via conjugation. This finding confirmed the key roles of these missing genes in conjugation. Further phylogenetic analysis suggested that ICEs in geographically close strains are also connected evolutionarily, and ICEPmiChn3 lost its conjugation cassette from a former mobile ICE. The identification and characterization of the three new members of the SXT/R391 family of ICEs in this work leads to suggestions of core ICE genes essential for conjugation, and extends understanding on the structures of ICEs, evolutionary relationships between ICEs, and the antimicrobial resistance mechanisms of P. mirabilis. Copyright © 2017 Elsevier B.V. and International Society of Chemotherapy. All rights reserved.

  3. Integrative modeling of eQTLs and cis-regulatory elements suggests mechanisms underlying cell type specificity of eQTLs.

    Directory of Open Access Journals (Sweden)

    Christopher D Brown

    Full Text Available Genetic variants in cis-regulatory elements or trans-acting regulators frequently influence the quantity and spatiotemporal distribution of gene transcription. Recent interest in expression quantitative trait locus (eQTL mapping has paralleled the adoption of genome-wide association studies (GWAS for the analysis of complex traits and disease in humans. Under the hypothesis that many GWAS associations tag non-coding SNPs with small effects, and that these SNPs exert phenotypic control by modifying gene expression, it has become common to interpret GWAS associations using eQTL data. To fully exploit the mechanistic interpretability of eQTL-GWAS comparisons, an improved understanding of the genetic architecture and causal mechanisms of cell type specificity of eQTLs is required. We address this need by performing an eQTL analysis in three parts: first we identified eQTLs from eleven studies on seven cell types; then we integrated eQTL data with cis-regulatory element (CRE data from the ENCODE project; finally we built a set of classifiers to predict the cell type specificity of eQTLs. The cell type specificity of eQTLs is associated with eQTL SNP overlap with hundreds of cell type specific CRE classes, including enhancer, promoter, and repressive chromatin marks, regions of open chromatin, and many classes of DNA binding proteins. These associations provide insight into the molecular mechanisms generating the cell type specificity of eQTLs and the mode of regulation of corresponding eQTLs. Using a random forest classifier with cell specific CRE-SNP overlap as features, we demonstrate the feasibility of predicting the cell type specificity of eQTLs. We then demonstrate that CREs from a trait-associated cell type can be used to annotate GWAS associations in the absence of eQTL data for that cell type. We anticipate that such integrative, predictive modeling of cell specificity will improve our ability to understand the mechanistic basis of human

  4. Elements for an integrated resource planning in the framework of river basins: a study for the Cuiaba River Basin; Elementos para um planejamento integrado de recursos no ambito de bacias hidrograficas: um estudo para a bacia do rio Cuiaba

    Energy Technology Data Exchange (ETDEWEB)

    Dorileo, Ivo Leandro; Bajay, Sergio Valdir [Universidade Estadual de Campinas (NIPE/UNICAMP), SP (Brazil). Nucleo Interdisciplinar de Planejamento Energetico. Dept. de Energia], e-mail: ildorileo@sigmanet.com.br, e-mail: bajay@fem.unicamp.br

    2008-07-01

    A new approach in energy planning in Brazil, IRP - Integrated Resources Planning for River Basins, gathers three main determinants of development: water, electricity and piped gas. This paper argues, briefly, the need of this planning, of indicative character, integrated with the River Basin Plans, and it presents a retrospective analysis concerning water, electricity and LPG demands of the economy sectors from Cuiaba River Basin region, priority elements to aid the prospective studies and to carry out process related to the IRP. (author)

  5. First steps of integrated spatial modeling of titanium, zirconium, and rare earth element resources within the Coastal Plain sediments of the southeastern United States

    Science.gov (United States)

    Ellefsen, Karl J.; Van Gosen, Bradley S.; Fey, David L.; Budahn, James R.; Smith, Steven M.; Shah, Anjana K.

    2015-01-01

    The Coastal Plain of the southeastern United States has extensive, unconsolidated sedimentary deposits that are enriched in heavy minerals containing titanium, zirconium, and rare earth element resources. Areas favorable for exploration and development of these resources are being identified by geochemical data, which are supplemented with geological, geophysical, hydrological, and geographical data. The first steps of this analysis have been completed. The concentrations of lanthanum, yttrium, and titanium tend to decrease as distance from the Piedmont (which is the likely source of these resources) increases and are moderately correlated with airborne measurements of equivalent thorium concentration. The concentrations of lanthanum, yttrium, and titanium are relatively high in those watersheds that adjoin the Piedmont, south of the Cape Fear Arch. Although this relation suggests that the concentrations are related to the watersheds, it may be simply an independent regional trend. The concentration of zirconium is unrelated to the distance from the Piedmont, the equivalent thorium concentration, and the watershed. These findings establish a foundation for more sophisticated analyses using integrated spatial modeling.

  6. Identifying Structure-Property Relationships Through DREAM.3D Representative Volume Elements and DAMASK Crystal Plasticity Simulations: An Integrated Computational Materials Engineering Approach

    Science.gov (United States)

    Diehl, Martin; Groeber, Michael; Haase, Christian; Molodov, Dmitri A.; Roters, Franz; Raabe, Dierk

    2017-05-01

    Predicting, understanding, and controlling the mechanical behavior is the most important task when designing structural materials. Modern alloy systems—in which multiple deformation mechanisms, phases, and defects are introduced to overcome the inverse strength-ductility relationship—give raise to multiple possibilities for modifying the deformation behavior, rendering traditional, exclusively experimentally-based alloy development workflows inappropriate. For fast and efficient alloy design, it is therefore desirable to predict the mechanical performance of candidate alloys by simulation studies to replace time- and resource-consuming mechanical tests. Simulation tools suitable for this task need to correctly predict the mechanical behavior in dependence of alloy composition, microstructure, texture, phase fractions, and processing history. Here, an integrated computational materials engineering approach based on the open source software packages DREAM.3D and DAMASK (Düsseldorf Advanced Materials Simulation Kit) that enables such virtual material development is presented. More specific, our approach consists of the following three steps: (1) acquire statistical quantities that describe a microstructure, (2) build a representative volume element based on these quantities employing DREAM.3D, and (3) evaluate the representative volume using a predictive crystal plasticity material model provided by DAMASK. Exemplarily, these steps are here conducted for a high-manganese steel.

  7. Standard elements; Elements standards

    Energy Technology Data Exchange (ETDEWEB)

    Blanc, B [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1958-07-01

    Following his own experience the author recalls the various advantages, especially in the laboratory, of having pre-fabricated vacuum-line components at his disposal. (author) [French] A la suite de sa propre experience, l'auteur veut rappeler les divers avantages que presente, tout particulierement en laboratoire, le fait d'avoir a sa disposition des elements pre-fabriques de canalisations a vide. (auteur)

  8. Integral or integrated marketing

    Directory of Open Access Journals (Sweden)

    Davčik Nebojša

    2006-01-01

    Full Text Available Marketing theorists and experts try to develop business efficient organization and to get marketing performance at higher, business integrated level since its earliest beginnings. The core issue in this paperwork is the dialectic and practical approach dilemma should we develop integrated or integral marketing approach in the organization. The presented company cases as well as dialectic and functional explanations of this dilemma clearly shows that integrated marketing is narrower approach than integral marketing if we take as focal point new, unique and completed entity. In the integration the essence is in getting different parts together, which do not have to make necessary the new entity. The key elements in the definition of the integral marketing are necessity and holistic, e.g. necessity to develop new, holistic entity.

  9. Element-topology-independent preconditioners for parallel finite element computations

    Science.gov (United States)

    Park, K. C.; Alexander, Scott

    1992-01-01

    A family of preconditioners for the solution of finite element equations are presented, which are element-topology independent and thus can be applicable to element order-free parallel computations. A key feature of the present preconditioners is the repeated use of element connectivity matrices and their left and right inverses. The properties and performance of the present preconditioners are demonstrated via beam and two-dimensional finite element matrices for implicit time integration computations.

  10. Artificial Leaks in Container Closure Integrity Testing: Nonlinear Finite Element Simulation of Aperture Size Originated by a Copper Wire Sandwiched between the Stopper and the Glass Vial.

    Science.gov (United States)

    Nieto, Alejandra; Roehl, Holger; Brown, Helen; Adler, Michael; Chalus, Pascal; Mahler, Hanns-Christian

    2016-01-01

    Container closure integrity (CCI) testing is required by different regulatory authorities in order to provide assurance of tightness of the container closure system against possible contamination, for example, by microorganisms. Microbial ingress CCI testing is performed by incubation of the container closure system with microorganisms under specified testing conditions. Physical CCI uses surrogate endpoints, such as coloration by dye solution ingress or gas flow (helium leakage testing). In order to correlate microbial CCI and physical CCI test methods and to evaluate the methods' capability to detect a given leak, artificial leaks are being introduced into the container closure system in a variety of different ways. In our study, artificial leaks were generated using inserted copper wires between the glass vial opening and rubber stopper. However, the insertion of copper wires introduces leaks of unknown size and shape. With nonlinear finite element simulations, the aperture size between the rubber stopper and the glass vial was calculated, depending on wire diameter and capping force. The dependency of the aperture size on the copper wire diameter was quadratic. With the data obtained, we were able to calculate the leak size and model leak shape. Our results suggest that the size as well as the shape of the artificial leaks should be taken into account when evaluating critical leak sizes, as flow rate does not, independently, correlate to hole size. Capping force also affected leak size. An increase in the capping force from 30 to 70 N resulted in a reduction of the aperture (leak size) by approximately 50% for all wire diameters. From 30 to 50 N, the reduction was approximately 33%. Container closure integrity (CCI) testing is required by different regulatory authorities in order to provide assurance of tightness of the container closure system against contamination, for example, by microorganisms. Microbial ingress CCI testing is performed by incubation of the

  11. Galvanic element. Galvanisches Element

    Energy Technology Data Exchange (ETDEWEB)

    Sprengel, D.; Haelbig, H.

    1980-01-03

    The invention concerns a gas-tight sealed accumulator with positive and negative electrode plates and an auxillary electrode electroconductively bound to the latter for suppressing oxygen pressure. The auxillary electrode is an intermediate film electrode. The film catalysing oxygen reduction is hydrophilic in character and the other film is hydrophobic. A double coated foil has proved to be advantageous, the hydrophilic film being formed from polymer-bound activated carbon and the hydrophrobic film from porous polytetrafluoroethylene. A metallic network of silver or nickel is rolled into the outer side of the activated carbon film. This auxillary electrode can be used to advantage in all galvanic elements. Even primary cells fall within the scope of application for auxillary electrodes because many of these contain a highly oxidized electrodic material which tends to give off oxygen.

  12. Genome-Wide Analysis of Transposon and Retroviral Insertions Reveals Preferential Integrations in Regions of DNA Flexibility.

    Science.gov (United States)

    Vrljicak, Pavle; Tao, Shijie; Varshney, Gaurav K; Quach, Helen Ngoc Bao; Joshi, Adita; LaFave, Matthew C; Burgess, Shawn M; Sampath, Karuna

    2016-04-07

    DNA transposons and retroviruses are important transgenic tools for genome engineering. An important consideration affecting the choice of transgenic vector is their insertion site preferences. Previous large-scale analyses of Ds transposon integration sites in plants were done on the basis of reporter gene expression or germ-line transmission, making it difficult to discern vertebrate integration preferences. Here, we compare over 1300 Ds transposon integration sites in zebrafish with Tol2 transposon and retroviral integration sites. Genome-wide analysis shows that Ds integration sites in the presence or absence of marker selection are remarkably similar and distributed throughout the genome. No strict motif was found, but a preference for structural features in the target DNA associated with DNA flexibility (Twist, Tilt, Rise, Roll, Shift, and Slide) was observed. Remarkably, this feature is also found in transposon and retroviral integrations in maize and mouse cells. Our findings show that structural features influence the integration of heterologous DNA in genomes, and have implications for targeted genome engineering. Copyright © 2016 Vrljicak et al.

  13. Limitless Analytic Elements

    Science.gov (United States)

    Strack, O. D. L.

    2018-02-01

    We present equations for new limitless analytic line elements. These elements possess a virtually unlimited number of degrees of freedom. We apply these new limitless analytic elements to head-specified boundaries and to problems with inhomogeneities in hydraulic conductivity. Applications of these new analytic elements to practical problems involving head-specified boundaries require the solution of a very large number of equations. To make the new elements useful in practice, an efficient iterative scheme is required. We present an improved version of the scheme presented by Bandilla et al. (2007), based on the application of Cauchy integrals. The limitless analytic elements are useful when modeling strings of elements, rivers for example, where local conditions are difficult to model, e.g., when a well is close to a river. The solution of such problems is facilitated by increasing the order of the elements to obtain a good solution. This makes it unnecessary to resort to dividing the element in question into many smaller elements to obtain a satisfactory solution.

  14. Integrating a logarithmic-strain based hyper-elastic formulation into a three-field mixed finite element formulation to deal with incompressibility in finite-strain elasto-plasticity

    International Nuclear Information System (INIS)

    Dina Al Akhrass; Bruchon, Julien; Drapier, Sylvain; Fayolle, Sebastien

    2014-01-01

    This paper deals with the treatment of incompressibility in solid mechanics in finite-strain elasto-plasticity. A finite-strain model proposed by Miehe, Apel and Lambrecht, which is based on a logarithmic strain measure and its work-conjugate stress tensor is chosen. Its main interest is that it allows for the adoption of standard constitutive models established in a small-strain framework. This model is extended to take into account the plastic incompressibility constraint intrinsically. In that purpose, an extension of this model to a three-field mixed finite element formulation is proposed, involving displacements, a strain variable and pressure as nodal variables with respect to standard finite element. Numerical examples of finite-strain problems are presented to assess the performance of the formulation. To conclude, an industrial case for which the classical under-integrated elements fail is considered. (authors)

  15. Evolutionary Process for Integrating COTS-Based Systems (EPIC): An Overview. Key Elements in Building, Fielding, and Supporting Commercial-off-the-Shelf (COTS) Based Solutions

    National Research Council Canada - National Science Library

    Albert, Cecilia

    2002-01-01

    .... The Evolutionary Process for Integrating COTS-based systems (EPIC) redefines acquisition, management, and engineering practices to more effectively leverage the COTS marketplace and other sources of pre-existing components...

  16. Photonics-on-a-chip: recent advances in integrated waveguides as enabling detection elements for real-world, lab-on-a-chip biosensing applications.

    Science.gov (United States)

    Washburn, Adam L; Bailey, Ryan C

    2011-01-21

    By leveraging advances in semiconductor microfabrication technologies, chip-integrated optical biosensors are poised to make an impact as scalable and multiplexable bioanalytical measurement tools for lab-on-a-chip applications. In particular, waveguide-based optical sensing technology appears to be exceptionally amenable to chip integration and miniaturization, and, as a result, the recent literature is replete with examples of chip-integrated waveguide sensing platforms developed to address a wide range of contemporary analytical challenges. As an overview of the most recent advances within this dynamic field, this review highlights work from the last 2-3 years in the areas of grating-coupled, interferometric, photonic crystal, and microresonator waveguide sensors. With a focus towards device integration, particular emphasis is placed on demonstrations of biosensing using these technologies within microfluidically controlled environments. In addition, examples of multiplexed detection and sensing within complex matrices--important features for real-world applicability--are given special attention.

  17. Transplutonium elements

    Energy Technology Data Exchange (ETDEWEB)

    Sivaramakrishnan, C. K.; Jadhav, A. V.; Reghuraman, K.; Mathew, K. A.; Nair, P. S.; Ramaniah, M. V.

    1973-07-01

    Research progress is reported on studies of the transplutonium elements including recovery and purification of americium, preparation of /sup 238/Pu, extraction studies using diethylhexyl phosphate. (DHM)

  18. Toxic Elements

    DEFF Research Database (Denmark)

    Hajeb, Parvaneh; Shakibazadeh, Shahram; Sloth, Jens Jørgen

    2016-01-01

    Food is considered the main source of toxic element (arsenic, cadmium, lead, and mercury) exposure to humans, and they can cause major public health effects. In this chapter, we discuss the most important sources for toxic element in food and the foodstuffs which are significant contributors to h...

  19. Dynamical analysis of a PWR internals using super-elements in an integrated 3-D model model. Part 2: dynamical tests and seismic analysis

    International Nuclear Information System (INIS)

    Jesus Miranda, C.A. de.

    1992-01-01

    The results of the test analysis (frequencies) for the isolated super-elements and for the developed 3-D model of the internals core support structures of a PWR research reactor are presented. Once certified of the model effectiveness for this type of analysis the seismic spectral analysis was performed. From the results can be seen that the structures are rigid for this load, isolated or together with the other in the 3-D model, and there are no impacts among them during the earthquake (OBE). (author)

  20. Fuel element

    International Nuclear Information System (INIS)

    Armijo, J.S.

    1976-01-01

    A fuel element for nuclear reactors is proposed which has a higher corrosion resisting quality in reactor operations. The zirconium alloy coating around the fuel element (uranium or plutonium compound) has on its inside a protection layer of metal which is metallurgically bound to the substance of the coating. As materials are namned: Alluminium, copper, niobium, stainless steel, and iron. This protective metallic layer has another inner layer, also metallurgically bound to its surface, which consists usually of a zirconium alloy. (UWI) [de

  1. The Needs for and the Basic Elements of an Integrated Approach to Planning, Organization and Management of Decommissioning Activities in the Russian Federation

    Energy Technology Data Exchange (ETDEWEB)

    Nechaev, A. F.; Akatov, A.A., E-mail: anechaev@lti-gti.ru, E-mail: andrey_akatov@mail.ru [Saint-Petersburg State Institute of Technology (Technical University), Saint-Petersburg (Russian Federation)

    2013-08-15

    This report contains the principal results of analytical studies performed by Research Group of St.-Petersburg State Institute of Technology in the framework of the IAEA CRP on ''Planning, Management and Organizational Aspects in Decommissioning of Nuclear Facilities''. The aims of the studies were to determine the adequacy of available tools and mechanisms for planning and organization of a large scale decommissioning and waste management activities; to define such elements of planning and management system that require changes and improvements; to elaborate recommendations on necessary actions; and to provide info analytical and methodical support for sustainable realization of decommissioning programme. Final report includes systematized information on a broad spectrum of issues related to CRP goals - from legislation, financing, subordination to concrete plans, projects, relevant manuals and guides addressed both to decision makers, technical executors and the public. (author)

  2. Survey of multidrug resistance integrative mobilizable elements SGI1 and PGI1 in Proteus mirabilis in humans and dogs in France, 2010-13.

    Science.gov (United States)

    Schultz, Eliette; Haenni, Marisa; Mereghetti, Laurent; Siebor, Eliane; Neuwirth, Catherine; Madec, Jean-Yves; Cloeckaert, Axel; Doublet, Benoît

    2015-09-01

    To characterize MDR genomic islands related to Salmonella genomic island 1 (SGI1) and Proteus genomic island 1 (PGI1) in Proteus mirabilis from human and animal sources in France in light of the previously reported cases. A total of 52 and 46 P. mirabilis clinical strains from human and animal sources, respectively, were studied for the period 2010-13. MDR was assessed by antimicrobial susceptibility testing, PCR detection of SGI1 and PGI1 and PCR mapping of the MDR regions. The diversity of the SGI1/PGI1-positive P. mirabilis strains was assessed by PFGE. Twelve P. mirabilis strains (5 humans and 7 dogs) were found to harbour an MDR island related to SGI1 or PGI1. Among them, several SGI1 variants were identified in diverse P. mirabilis genetic backgrounds. The variant SGI1-V, which harbours the ESBL bla VEB-6 gene, was found in closely genetically related human and dog P. mirabilis strains. The recently described PGI1 element was also identified in human and dog strains. Finally, one strain harboured a novel SGI genomic island closely related to SGI1 and SGI2 without an insertion of the MDR region. This study reports for the first time, to our knowledge, SGI1-positive and PGI1-positive P. mirabilis strains from dogs in France. The genetic diversity of the strains suggests several independent horizontal acquisitions of these MDR elements. The potential transmission of SGI1/PGI1-positive P. mirabilis strains between animals and humans is of public health concern, notably with regard to the spread of ESBL and carbapenemase genes, i.e. bla VEB-6 and bla NDM-1. © The Author 2015. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  3. PELTIER ELEMENTS

    CERN Document Server

    Tani, Laurits

    2015-01-01

    To control Peltier elements, temperature controller was used. I used TEC-1091 that was manufactured my Meerstetter Engineering. To gain control with the temperature controller, software had to be intalled on a controlling PC. There were different modes to control the Peltier: Tempererature controller to control temperature, Static current/voltage to control voltage and current and LIVE ON/OFF to auto-tune the controller respectively to the system. Also, since near the collision pipe there is much radiation, radiation-proof Peltier elements have to be used. To gain the best results, I had to find the most efficient Peltier elements and try to get their cold side to -40 degrees Celsius.

  4. Fuel element

    International Nuclear Information System (INIS)

    Kennedy, S.T.

    1982-01-01

    A nuclear reactor fuel element wherein a stack of nuclear fuel is prevented from displacement within its sheath by a retainer comprising a tube member which is radially expanded into frictional contact with the sheath by means of a captive ball within a tapered bore. (author)

  5. Transactinide elements

    International Nuclear Information System (INIS)

    Hemingway, J.D.

    1975-01-01

    The review is covered in sections, entitled: predicted nuclear properties - including closed shells, decay characteristics; predicted chemical properties - including electronic structure and calculated properties, X-radiation, extrapolated chemical properties, separation chemistry; methods of synthesis; the natural occurrence of superheavy elements. (U.K.)

  6. Utilization of Large Cohesive Interface Elements for Delamination Simulation

    DEFF Research Database (Denmark)

    Bak, Brian Lau Verndal; Lund, Erik

    2012-01-01

    This paper describes the difficulties of utilizing large interface elements in delamination simulation. Solutions to increase the size of applicable interface elements are described and cover numerical integration of the element and modifications of the cohesive law....

  7. New elements

    International Nuclear Information System (INIS)

    Flerov, G.

    1976-01-01

    The history is briefly described of the investigation of superheavy elements at the Joint Institute for Nuclear Research at Dubna. The significance of the investigation is assessed from the point of view of the nuclear structure study and major problems encountered in experimental efforts are indicated. Current experimental methods aiming at the discovery or the production of superheavy nuclei with Z approximately 114 are listed. (I.W.)

  8. Radiographic element

    International Nuclear Information System (INIS)

    Abbott, T.I.; Jones, C.G.

    1984-01-01

    Radiographic elements are disclosed comprised of first and second silver halide emulsion layers separated by an interposed support capable of transmitting radiation to which the second image portion is responsive. At least the first imaging portion contains a silver halide emulsion in which thin tubular silver halide grains of intermediate aspect ratios (from 5:1 to 8:1) are present. Spectral sensitizing dye is adsorbed to the surface of the tubular grains. Increased photographic speeds can be realized at comparable levels of crossover. (author)

  9. Superheavy elements

    CERN Document Server

    Hofmann, S

    1999-01-01

    The outstanding aim of experimental investigations of heavy nuclei is the exploration of spherical 'SuperHeavy Elements' (SHEs). On the basis of the nuclear shell model, the next double magic shell-closure beyond sup 2 sup 0 sup 8 Pb is predicted at proton numbers between Z=114 and 126 and at neutron number N=184. All experimental efforts aiming at identifying SHEs (Z>=114) were negative so far. A highly sensitive search experiment was performed in November-December 1995 at SHIP. The isotope sup 2 sup 9 sup 0 116 produced by 'radiative capture' was searched for in the course of a 33 days irradiation of a sup 2 sup 0 sup 8 Pb target with sup 8 sup 2 Se projectiles, however, only cross-section limits were measured. Positive results were obtained in experiments searching for elements from 110 to 112 using cold fusion and the 1n evaporation channel. The produced isotopes were unambiguously identified by means of alpha-alpha correlations. Not fission, but alpha emission is the dominant decay mode. The measurement ...

  10. Functional Integration

    Science.gov (United States)

    Cartier, Pierre; DeWitt-Morette, Cecile

    2010-06-01

    Acknowledgements; List symbols, conventions, and formulary; Part I. The Physical and Mathematical Environment: 1. The physical and mathematical environment; Part II. Quantum Mechanics: 2. First lesson: gaussian integrals; 3. Selected examples; 4. Semiclassical expansion: WKB; 5. Semiclassical expansion: beyond WKB; 6. Quantum dynamics: path integrals and operator formalism; Part III. Methods from Differential Geometry: 7. Symmetries; 8. Homotopy; 9. Grassmann analysis: basics; 10. Grassmann analysis: applications; 11. Volume elements, divergences, gradients; Part IV. Non-Gaussian Applications: 12. Poisson processes in physics; 13. A mathematical theory of Poisson processes; 14. First exit time: energy problems; Part V. Problems in Quantum Field Theory: 15. Renormalization 1: an introduction; 16. Renormalization 2: scaling; 17. Renormalization 3: combinatorics; 18. Volume elements in quantum field theory Bryce DeWitt; Part VI. Projects: 19. Projects; Appendix A. Forward and backward integrals: spaces of pointed paths; Appendix B. Product integrals; Appendix C. A compendium of gaussian integrals; Appendix D. Wick calculus Alexander Wurm; Appendix E. The Jacobi operator; Appendix F. Change of variables of integration; Appendix G. Analytic properties of covariances; Appendix H. Feynman's checkerboard; Bibliography; Index.

  11. Fuel element

    International Nuclear Information System (INIS)

    Hirose, Yasuo.

    1982-01-01

    Purpose: To increase the plenum space in a fuel element used for a liquid metal cooled reactor. Constitution: A fuel pellet is secured at one end with an end plug and at the other with a coil spring in a tubular container. A mechanism for fixing the coil spring composed of a tubular unit is mounted by friction with the inner surface of the tubular container. Accordingly, the recoiling force of the coil spring can be retained by fixing mechanism with a small volume, and since a large amount of plenum space can be obtained, the internal pressure rise in the cladding tube can be suppressed even if large quantities of fission products are discharged. (Kamimura, M.)

  12. A unified architecture of transcriptional regulatory elements

    DEFF Research Database (Denmark)

    Andersson, Robin; Sandelin, Albin Gustav; Danko, Charles G.

    2015-01-01

    Gene expression is precisely controlled in time and space through the integration of signals that act at gene promoters and gene-distal enhancers. Classically, promoters and enhancers are considered separate classes of regulatory elements, often distinguished by histone modifications. However...... and enhancers are considered a single class of functional element, with a unified architecture for transcription initiation. The context of interacting regulatory elements and the surrounding sequences determine local transcriptional output as well as the enhancer and promoter activities of individual elements....

  13. Integrated System Validation Usability Questionnaire: Information Display Element; Desarrollo del Cuestionario de Facilidad de Uso para la Validación de Sistemas Integrados: Displays de Información

    Energy Technology Data Exchange (ETDEWEB)

    Garcés, Ma. I.; Torralba, B.

    2015-07-01

    The Research and Development (R&D) project on “Theoretical and Methodological Approaches to Integrated System Validation of Control Rooms, 2014-2015”, in which the research activities described in this report are framed, has two main objectives: to develop the items for an usability methodology conceived as a part of the measurement framework for performance-based control room evaluation that the OECD Halden Reactor Project will test in the experiments planned for 2015; and the statistical analysis of the data generated in the experimental activities of the Halden Man-Machine Laboratory (HAMMLAB) facility, with previous usability questionnaires, in 2010 and 2011. In this report, the procedure designed to meet the first goal of the project is described, in particular, the process followed to identify the items related to information displays, one of the elements to be included in the usability questionnaire. Three phases are performed, in the first one, the approaches developed by the United States Nuclear Regulatory Commission, NRC, are reviewed and the models proposed by the nuclear energy industry and their technical support organizations, mainly, the United States Electric Power Research Institute, EPRI, are analyzed. In the remaining stages, general and specific guidelines for information displays, in particular, display pages, formats, elements and data quality and update rate recommendations are compared and criteria for the preliminary selection of the items that should be incorporated into the usability questionnaire are defined. This proposal will be reviewed and adapted by the Halden Reactor Project to the design of the specific experiments performed in HAMMLAB.

  14. Event marketing with multi-element integration for sci-tech journals%基于事件营销的科技期刊多元素融合营销策略

    Institute of Scientific and Technical Information of China (English)

    张扬; 朱拴成

    2012-01-01

    The paper is targeted at the problems of monotonous business pattern, old-fashioned marketing programs and the inability to meet the increasingly higher customer requirements in the advertising operation for sci-tech journals. We propose that sci- tech journals should help enterprises to plan event marketing according to the factors such as enterprise publicity and marketing demands, and sell the marketing strategies to enterprises in this process. In event marketing, sci-tech journals should integrate as much as possible a number of associated elements to influence each other and achieve a win-win cooperation. Through analysis of several marketing cases, it is suggested that the muhi-element event marketing is an effective marketing strategy for sci-tech journals.%针对科技期刊在广告经营中模式单一、营销方案老套、客户要求越来越高等问题,提出科技期刊应根据企业宣传和营销诉求等因素帮助企业策划事件营销,并在这个过程中向企业进行广告销售的营销策略。认为在事件营销过程中,科技期刊应尽可能融合较多的关联元素,使其相互影响,实现共赢。通过对多个营销案例的分析,证明融入多元素的事件营销是科技期刊行之有效的营销策略。

  15. Improved nuclear fuel element

    International Nuclear Information System (INIS)

    Klepfer, H.H.

    1974-01-01

    A nuclear fuel element is described which comprises: 1) an elongated clad container, 2) a layer of high lubricity material being disposed in and adjacent to the clad container, 3) a low neutron capture cross section metal liner being disposed in the clad container and adjacent to the layer, 4) a central core of a body of nuclear fuel material disposed in and partially filling the container and forming an internal cavity in the container, 5) an enclosure integrally secured and sealed at each end of the container, and a nuclear fuel material retaining means positioned in the cavity. (author)

  16. Technical Elements (CCT1)

    DEFF Research Database (Denmark)

    Thomsen, Kirsten Engelund; Wittchen, Kim Bjarne

    2017-01-01

    Many of the aspects dealt with in the CA EPBD are closely interlinked with each other and may refer to both new and existing buildings, as well as to inspection and certification. This is also true for technical aspects, such as the calculation methodologies, and how to include technical systems......’ efficiency or how to integrate renewable energy within them. The central team for Technical Elements deals with issues of a technical nature, which are common to new and existing buildings, and/or with minimum demands, certification and inspection. This report focuses on the implementation of Articles 3, 4...

  17. Nuclear fuel element leak detection system

    International Nuclear Information System (INIS)

    John, C.D. Jr.

    1978-01-01

    Disclosed is a leak detection system integral with a wall of a building used to fabricate nuclear fuel elements for detecting radiation leakage from the nuclear fuel elements as the fuel elements exit the building. The leak detecting system comprises a shielded compartment constructed to withstand environmental hazards extending into a similarly constructed building and having sealed doors on both ends along with leak detecting apparatus connected to the compartment. The leak detecting system provides a system for removing a nuclear fuel element from its fabrication building while testing for radiation leaks in the fuel element

  18. Quadrature representation of finite element variational forms

    DEFF Research Database (Denmark)

    Ølgaard, Kristian Breum; Wells, Garth N.

    2012-01-01

    This chapter addresses the conventional run-time quadrature approach for the numerical integration of local element tensors associated with finite element variational forms, and in particular automated optimizations that can be performed to reduce the number of floating point operations...

  19. Nuclear fuel element end fitting

    International Nuclear Information System (INIS)

    Jabsen, F.S.

    1979-01-01

    A typical embodiment of the invention has an array of sockets that are welded to the intersections of the plates that form the upper and lower end fittings of a nuclear reactor fuel element. The sockets, which are generally cylindrical in shape, are oriented in directions that enable the longitudinal axes of the sockets to align with the longitudinal axes of the fuel rods that are received in the respective sockets. Detents impressed in the surfaces of the sockets engage mating grooves that are formed in the ends of the fuel rods to provide for the structural integrity of the fuel element

  20. Spin chains and Gustafson's integrals

    International Nuclear Information System (INIS)

    Derkachov, S.E; Manashov, A.N.; Regensburg Univ.

    2016-12-01

    The Gustafson's integrals are the multidimensional generalization of the classical Mellin-Barnes integrals. We show that some of these integrals arise from relations between matrix elements in the Sklyanin's representation of Separated Variables in the spin chain models. We also present several new integrals.

  1. Thermal support elements (TTE) made of high-tensile fibre-reinforced material and integrated vacuum-insulation panels (VIP) - Final report; Thermotragelemente (TTE) aus hochfestem Faserverbundstoff und integrierten Vakuumisolationspaneelen (VIP) - Schlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Motavalli, M.; Ghazi Wakili, K.; Gsell, D.; Herwig, A.

    2008-07-01

    In this project, the static and thermal characteristics of the balcony connection element TTE (load carrying thermo-element) of the Hitek Construction Company AG were investigated. The TTE is an innovative element, which minimises thermal bridges that always exist in the vicinity of balcony connections. The concept of the element relies of the ability of fibre reinforced composites with superior thermal and mechanical characteristics to transfer the high mechanical loads from the balcony, through the layer of insulation, to the building. From a mechanical point-of-view, only very limited use of fibre reinforced composites has been seen for this type of construction application, therefore necessitating a detailed investigation of the element. In a first step, component tests of the individual load carrying elements were carried out, in which the elements showed an entirely satisfactory short-term behaviour. Furthermore, several assembly tests were carried out whereby parts of the balcony were reproduced, loaded and observed over longer term. During the investigations it was seen that very high stresses occur in the compression zone of the concrete deck and that the element must be modified in the future. From a thermal point-of-view, the TTE element offers a considerable improvement as compared with concrete decks without a thermal discontinuity. The thermal properties of the TTE element can be considered similar to or slightly better than other thermally discontinuous systems with the same load carrying capacity. This is understandable, since a thicker insulating layer with a thermal resistance of 2.5 m{sup 2} K/W was partially replaced through a thinner, yet more efficient insulation with a thermal resistance of 1.9 m{sup 2} K/W. Moreover, the glass fibre reinforced polymer has a larger thermal resistance than steel. The results obtained from the mechanical and thermal tests point to the need for further optimisation of the TTE element. It has been seen, however

  2. Discrete Element Modeling

    Energy Technology Data Exchange (ETDEWEB)

    Morris, J; Johnson, S

    2007-12-03

    The Distinct Element Method (also frequently referred to as the Discrete Element Method) (DEM) is a Lagrangian numerical technique where the computational domain consists of discrete solid elements which interact via compliant contacts. This can be contrasted with Finite Element Methods where the computational domain is assumed to represent a continuum (although many modern implementations of the FEM can accommodate some Distinct Element capabilities). Often the terms Discrete Element Method and Distinct Element Method are used interchangeably in the literature, although Cundall and Hart (1992) suggested that Discrete Element Methods should be a more inclusive term covering Distinct Element Methods, Displacement Discontinuity Analysis and Modal Methods. In this work, DEM specifically refers to the Distinct Element Method, where the discrete elements interact via compliant contacts, in contrast with Displacement Discontinuity Analysis where the contacts are rigid and all compliance is taken up by the adjacent intact material.

  3. A first course in finite elements

    CERN Document Server

    Fish, Jacob

    2007-01-01

    Developed from the authors, combined total of 50 years undergraduate and graduate teaching experience, this book presents the finite element method formulated as a general-purpose numerical procedure for solving engineering problems governed by partial differential equations.  Focusing on the formulation and application of the finite element method through the integration of finite element theory, code development, and software application, the book is both introductory and self-contained, as well as being a hands-on experience for any student. This authoritative text on Finite Elements:Adopts

  4. Revised genomic consensus for the hypermethylated CpG island region of the human L1 transposon and integration sites of full length L1 elements from recombinant clones made using methylation-tolerant host strains

    DEFF Research Database (Denmark)

    Crowther, P J; Doherty, J P; Linsenmeyer, M E

    1991-01-01

    preferentially from L1 members which have accumulated mutations that have removed sites of methylation. We present a revised consensus from the 5' presumptive control region of these elements. This revised consensus contains a consensus RNA polymerase III promoter which would permit the synthesis of transcripts......Efficient recovery of clones from the 5' end of the human L1 dispersed repetitive elements necessitates the use of deletion mcr- host strains since this region contains a CpG island which is hypermethylated in vivo. Clones recovered with conventional mcr+ hosts seem to have been derived...... from the 5' end of full length L1 elements. Such potential transcripts are likely to exhibit a high degree of secondary structure. In addition, we have determined the flanking sequences for 6 full length L1 elements. The majority of full length L1 clones show no convincing evidence for target site...

  5. Chemistry of the elements

    International Nuclear Information System (INIS)

    Greenwood, N.N.; Earnshaw, A.

    1984-01-01

    This textbook presents an account of the chemistry of the elements for both undergraduate and postgraduate students. It covers not only the 'inorganic' chemistry of the elements, but also analytical, theoretical, industrial, organometallic;, bio-inorganic and other areas of chemistry which apply. The following elements of special nuclear interest are included: Rb, Cs, Fr, Sr, Ba, Ra, Po, At, Rn, Sc, Y, Zr, Hf, V, Nb, Ta, Mo, Tc, Ru, the Lanthanide Elements, the Actinide Elements. (U.K.)

  6. Fuel element concept for long life high power nuclear reactors

    Science.gov (United States)

    Mcdonald, G. E.; Rom, F. E.

    1969-01-01

    Nuclear reactor fuel elements have burnups that are an order of magnitude higher than can currently be achieved by conventional design practice. Elements have greater time integrated power producing capacity per unit volume. Element design concept capitalizes on known design principles and observed behavior of nuclear fuel.

  7. Building integrated photovoltaic; Photovaltaique integre aux batiments

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-01-01

    Durable, modular and flexible in use, as demonstrated by the different case studies in this publication, photovoltaic can replace diverse building elements, from glass facades to weather proof roofs. This leaflet towards architects describes aesthetic, technical, economic and environmental interest of building integrated photovoltaic. (author)

  8. Data Element Registry Services

    Data.gov (United States)

    U.S. Environmental Protection Agency — Data Element Registry Services (DERS) is a resource for information about value lists (aka code sets / pick lists), data dictionaries, data elements, and EPA data...

  9. Basic Finite Element Method

    International Nuclear Information System (INIS)

    Lee, Byeong Hae

    1992-02-01

    This book gives descriptions of basic finite element method, which includes basic finite element method and data, black box, writing of data, definition of VECTOR, definition of matrix, matrix and multiplication of matrix, addition of matrix, and unit matrix, conception of hardness matrix like spring power and displacement, governed equation of an elastic body, finite element method, Fortran method and programming such as composition of computer, order of programming and data card and Fortran card, finite element program and application of nonelastic problem.

  10. Radiolabelled cellular blood elements

    International Nuclear Information System (INIS)

    Sinzinger, H.

    1990-01-01

    This book reports on radiolabelled cellular blood elements, covering new advances made during the past several years, in particular the use of Tc-99 as a tracer for blood elements. Coverage extends to several radiolabelled monoclonal antibodies that are specific for blood components and may label blood elements in vivo

  11. Dietary patterns and trace elements intake evaluation

    International Nuclear Information System (INIS)

    Rahman, A.; Waheed, S.; Zaidi, J.H.; Ahmad, S.

    1998-01-01

    The dietary patterns and trace element contents of the integrated diets of middle income population in Gujranwala and of Islamabad have been studied and dietary intake of winter and summer are given. An overview of the elemental concentration in the two sets of integrated diets reveals similar zinc and manganese concentrations; comparatively higher nickel, selenium and potassium concentrations in Gujranwala and higher chromium, cesium, scandium, sodium and chlorine concentrations in Islamabad. These results undoubtedly reflect the difference in food selection and habits of the two populations, the influence of soil content and industrial pollution

  12. Rare (Earth Elements [score

    Directory of Open Access Journals (Sweden)

    Camilo Méndez

    2014-12-01

    Full Text Available Rare (Earth Elements is a cycle of works for solo piano. The cycle was inspired by James Dillon’s Book of Elements (Vol. I-V. The complete cycle will consist of 14 pieces; one for each selected rare (earth element. The chosen elements are Neodymium, Erbium, Tellurium, Hafnium, Tantalum, Technetium, Indium, Dysprosium, Lanthanium, Cerium, Europium, Terbium, Yttrium and Darmstadtium. These elements were selected due to their special atomic properties that in many cases make them extremely valuable for the development of new technologies, and also because of their scarcity. To date, only 4 works have been completed Yttrium, Technetium, Indium and Tellurium.

  13. Generalized finite elements

    International Nuclear Information System (INIS)

    Wachspress, E.

    2009-01-01

    Triangles and rectangles are the ubiquitous elements in finite element studies. Only these elements admit polynomial basis functions. Rational functions provide a basis for elements having any number of straight and curved sides. Numerical complexities initially associated with rational bases precluded extensive use. Recent analysis has reduced these difficulties and programs have been written to illustrate effectiveness. Although incorporation in major finite element software requires considerable effort, there are advantages in some applications which warrant implementation. An outline of the basic theory and of recent innovations is presented here. (authors)

  14. Elements beyond uranium

    International Nuclear Information System (INIS)

    Seaborg, G.T.; Loveland, W.D.

    1990-01-01

    This book is the 12th volume in a series on transuranium elements. Varied techniques for production of these elements, the methods used in the identification, and the exquisitely refined microchemical techniques required to deal wth samples sometimes involving only a few atoms are described in detail. The chapter on synthesis of the new elements is liberally laced with reminiscences of the proud progenitors as well as the criteria for the discovery of a new chemical element. The authors lament that the superheavy elements (elements in the region of atomic number 114) still elude detection even though their creation should be possible, and some, at least, should survive long enough to be detected. One chapter in the book is devoted to practical applictions of uranium, and the transuranic elements

  15. Transuranic element behavior in soils and plants

    International Nuclear Information System (INIS)

    Wildung, R.E.

    1982-01-01

    The principal objective of this study is to define soil, plant, and foliar interaction processes that influence the availability of transuranic elements to agricultural plants and animals as a basis for improved modeling and dose-assessment. Major areas of emphasis are: (1) soil and soil-microbial processes that influence the concentration and form of transuranic elements in soil solutions and availability to the plant root with time; (2) deposition and plant interception of airborne submicronic particles containing transuranic elements and their susceptibility to leaching; (3) plant processes that influence transport across plant root membrane and foliar surfaces, as well as the form and sites of deposition of transuranic elements in mature plants; and (4) the integrated effect of soil and plant processes on transuranic element availability to, and form in, animals that consume plants

  16. Experimental research of fuel element reliability

    International Nuclear Information System (INIS)

    Cech, B.; Novak, J.; Chamrad, B.

    1980-01-01

    The rate and extent of the damage of the can integrity for fission products is the basic criterion of reliability. The extent of damage is measurable by the fission product leakage into the reactor coolant circuit. An analysis is made of the causes of the fuel element can damage and a model is proposed for testing fuel element reliability. Special experiments should be carried out to assess partial processes, such as heat transfer and fuel element surface temperature, fission gas liberation and pressure changes inside the element, corrosion weakening of the can wall, can deformation as a result of mechanical interactions. The irradiation probe for reliability testing of fuel elements is described. (M.S.)

  17. Integral-preserving integrators

    International Nuclear Information System (INIS)

    McLaren, D I; Quispel, G R W

    2004-01-01

    Ordinary differential equations having a first integral may be solved numerically using one of several methods, with the integral preserved to machine accuracy. One such method is the discrete gradient method. It is shown here that the order of the method can be bootstrapped repeatedly to higher orders of accuracy. The method is illustrated using the Henon-Heiles system. (letter to the editor)

  18. Advanced Manufacturing Technologies (AMT): Composites Integrated Modeling

    Data.gov (United States)

    National Aeronautics and Space Administration — The Composites Integrated Modeling (CIM) Element developed low cost, lightweight, and efficient composite structures, materials and manufacturing technologies with...

  19. Lustre filesystem for CMS storage element (SE)

    International Nuclear Information System (INIS)

    Wu, Y; Kim, B; Avery, P; Fu, Y; Bourilkov, D; Taylor, C; Prescott, C; Rodriguez, J

    2011-01-01

    This paper presents our effort to integrate the Lustre filesystem with BeStMan, GridFTP and Ganglia to make it a fully functional WLCG SE (Storage Element). We first describe the configuration of our Lustre filesystem at the University of Florida and our integration process. We then present benchmark performance figures and IO rates from the CMS analysis jobs and the WAN data transfer performance that are conducted on the Lustre SE.

  20. Application of FIRE for the calculation of photon matrix elements

    Indian Academy of Sciences (India)

    to evaluate the two-loop Feynman diagrams for the photon matrix element of the ... sum of scalar Feynman integrals to a linear combination of a few master integrals. .... Then, FIRE is used to express these scalar integrals as a linear combi-.

  1. Noncoding Elements: Evolution and Epigenetic Regulation

    KAUST Repository

    Seridi, Loqmane

    2016-03-09

    When the human genome project was completed, it revealed a surprising result. 98% of the genome did not code for protein of which more than 50% are repeats— later known as ”Junk DNA”. However, comparative genomics unveiled that many noncoding elements are evolutionarily constrained; thus luckily to have a role in genome stability and regulation. Though, their exact functions remained largely unknown. Several large international consortia such as the Functional Annotation of Mammalian Genomes (FANTOM) and the Encyclopedia of DNA Elements (ENCODE) were set to understand the structure and the regulation of the genome. Specifically, these endeavors aim to measure and reveal the transcribed components and functional elements of the genome. One of the most the striking findings of these efforts is that most of the genome is transcribed, including non-conserved noncoding elements and repeat elements. Specifically, we investigated the evolution and epigenetic properties of noncoding elements. 1. We compared genomes of evolutionarily distant species and showed the ubiquity of constrained noncoding elements in metazoa. 2. By integrating multi-omic data (such as transcriptome, nucleosome profiling, histone modifications), I conducted a comprehensive analysis of epigenetic properties (chromatin states) of conserved noncoding elements in insects. We showed that those elements have distinct and protective sequence features, undergo dynamic epigenetic regulation, and appear to be associated with the structural components of the chromatin, replication origins, and nuclear matrix. 3. I focused on the relationship between enhancers and repetitive elements. Using Cap Analysis of Gene Expression (CAGE) and RNASeq, I compiled a full catalog of active enhancers (a class of noncoding elements) during myogenesis of human primary cells of healthy donors and donors affected by Duchenne muscular dystrophy (DMD). Comparing the two time-courses, a significant change in the epigenetic

  2. Integrated security system definition

    International Nuclear Information System (INIS)

    Campbell, G.K.; Hall, J.R. II

    1985-01-01

    The objectives of an integrated security system are to detect intruders and unauthorized activities with a high degree of reliability and the to deter and delay them until effective response/engagement can be accomplished. Definition of an effective integrated security system requires proper application of a system engineering methodology. This paper summarizes a methodology and describes its application to the problem of integrated security system definition. This process includes requirements identification and analysis, allocation of identified system requirements to the subsystem level and provides a basis for identification of synergistic subsystem elements and for synthesis into an integrated system. The paper discusses how this is accomplished, emphasizing at each step how system integration and subsystem synergism is considered. The paper concludes with the product of the process: implementation of an integrated security system

  3. The solar element

    DEFF Research Database (Denmark)

    Kragh, Helge

    2009-01-01

    of the nineteenth century. In the modest form of a yellow spectral line known as D3, 'helium' was sometimes supposed to exist in the Sun's atmosphere, an idea which is traditionally ascribed to J. Norman Lockyer. Did Lockyer discover helium as a solar element? How was the suggestion received by chemists, physicists...... and astronomers in the period until the spring of 1895, when William Ramsay serendipitously found the gas in uranium minerals? The hypothetical element helium was fairly well known, yet Ramsay's discovery owed little or nothing to Lockyer's solar element. Indeed, for a brief while it was thought that the two...... elements might be different. The complex story of how helium became established as both a solar and terrestrial element involves precise observations as well as airy speculations. It is a story that is unique among the discovery histories of the chemical elements....

  4. The synthetic elements

    Energy Technology Data Exchange (ETDEWEB)

    Hoffman, D.C.

    1990-05-01

    Prior to 1940, the heaviest element known was uranium, discovered in 1789. Since that time the elements 93 through 109 have been synthesized and identified and the elements 43, 61, 85, and 87 which were missing form the periodic tables of the 1930's have been discovered. The techniques and problems involved in these discoveries and the placement of the transuranium elements in the periodic table will be discussed. The production and positive identification of elements heavier than Md (Z=101), which have very short half-lives and can only be produced an atom-at-a-time, are very difficult and there have been controversies concerning their discovery. Some of the new methods which have been developed and used in these studies will be described. The prospects for production of still heavier elements will be considered.

  5. The synthetic elements

    International Nuclear Information System (INIS)

    Hoffman, D.C.

    1990-05-01

    Prior to 1940, the heaviest element known was uranium, discovered in 1789. Since that time the elements 93 through 109 have been synthesized and identified and the elements 43, 61, 85, and 87 which were missing form the periodic tables of the 1930's have been discovered. The techniques and problems involved in these discoveries and the placement of the transuranium elements in the periodic table will be discussed. The production and positive identification of elements heavier than Md (Z=101), which have very short half-lives and can only be produced an atom-at-a-time, are very difficult and there have been controversies concerning their discovery. Some of the new methods which have been developed and used in these studies will be described. The prospects for production of still heavier elements will be considered

  6. Fuel element loading system

    International Nuclear Information System (INIS)

    Arya, S.P; s.

    1978-01-01

    A nuclear fuel element loading system is described which conveys a plurality of fuel rods to longitudinal passages in fuel elements. Conveyor means successively position the fuel rods above the longitudinal passages in axial alignment therewith and adapter means guide the fuel rods from the conveyor means into the longitudinal passages. The fuel elements are vibrated to cause the fuel rods to fall into the longitudinal passages through the adapter means

  7. Elements in biological AMS

    International Nuclear Information System (INIS)

    Vogel, J.S.; McAninch, J.; Freeman, S.

    1996-08-01

    AMS (Accelerator Mass Spectrometry) provides high detection sensitivity for isotopes whose half-lives are between 10 years and 100 million years. 14 C is the most developed of such isotopes and is used in tracing natural and anthropogenic organic compounds in the Earth's biosphere. Thirty-three elements in the main periodic table and 17 lanthanides or actinides have long lived isotopes, providing potential tracers for research in elemental biochemistry. Overlap of biologically interesting heavy elements and possible AMS tracers is discussed

  8. Analogs for transuranic elements

    International Nuclear Information System (INIS)

    Weimer, W.C.; Laul, J.C.; Kutt, J.C.

    1981-01-01

    A combined theoretical and experimental approach is being used to estimate the long-term environmental and biogeochemical behaviors of selected transuranic elements. The objective of this research is to estimate the effect that long-term (hundreds of years) environmental weathering has on the behavior of the transuranic elements americium and curium. This is achieved by investigating the actual behavior of naturally occurring rare earth elements, especially neodymium, that serve as transuranic analogs. Determination of the analog element behavior provides data that can be used to estimate the ultimate availability to man of transuranic materials released into the environment

  9. Chemistry of superheavy elements

    International Nuclear Information System (INIS)

    Schaedel, M.

    2012-01-01

    The chemistry of superheavy elements - or transactinides from their position in the Periodic Table - is summarized. After giving an overview over historical developments, nuclear aspects about synthesis of neutron-rich isotopes of these elements, produced in hot-fusion reactions, and their nuclear decay properties are briefly mentioned. Specific requirements to cope with the one-atom-at-a-time situation in automated chemical separations and recent developments in aqueous-phase and gas-phase chemistry are presented. Exciting, current developments, first applications, and future prospects of chemical separations behind physical recoil separators ('pre-separator') are discussed in detail. The status of our current knowledge about the chemistry of rutherfordium (Rf, element 104), dubnium (Db, element 105), seaborgium (Sg, element 106), bohrium (Bh, element 107), hassium (Hs, element 108), copernicium (Cn, element 112), and element 114 is discussed from an experimental point of view. Recent results are emphasized and compared with empirical extrapolations and with fully-relativistic theoretical calculations, especially also under the aspect of the architecture of the Periodic Table. (orig.)

  10. Recent advances in boundary element methods

    CERN Document Server

    Manolis, GD

    2009-01-01

    Addresses the needs of the computational mechanics research community in terms of information on boundary integral equation-based methods and techniques applied to a variety of fields. This book collects both original and review articles on contemporary Boundary Element Methods (BEM) as well as on the Mesh Reduction Methods (MRM).

  11. Seagrass leaf element content

    NARCIS (Netherlands)

    Vonk, J.A.; Smulders, Fee O.H.; Christianen, Marjolijn J.A.; Govers, Laura L.

    2017-01-01

    Knowledge on the role of seagrass leaf elements and in particular micronutrients and their ranges is limited. We present a global database, consisting of 1126 unique leaf values for ten elements, obtained from literature and unpublished data, spanning 25 different seagrass species from 28 countries.

  12. Berkeley new element program

    International Nuclear Information System (INIS)

    Ghiorso, A.

    1975-09-01

    The work done with element 106 is reviewed, and a new experiment which bears on the properties of the isotope of mass 260 with atomic number 104 is discussed. It is noted that in the case of element 106 a link is demonstrated to the granddaughter as well as the daughter

  13. Elemental Food for Thought

    Science.gov (United States)

    Cady, Susan

    2005-01-01

    One of the first tasks students learn in chemistry is to pronounce and spell the names of elements and learn their corresponding chemical symbols. Repetitive oral recitation is commonly used to learn this information, but games and puzzles can make this task creative, variable, and fun. Elemental Food for Thought is a puzzlelike activity that…

  14. Nuclear fuel element

    International Nuclear Information System (INIS)

    Mogard, J.H.

    1977-01-01

    A nuclear fuel element is disclosed for use in power producing nuclear reactors, comprising a plurality of axially aligned ceramic cylindrical fuel bodies of the sintered type, and a cladding tube of metal or metal alloys, wherein said cladding tube on its cylindrical inner surface is provided with a plurality of slightly protruding spacing elements distributed over said inner surface

  15. Proceedings of transuranium elements

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    The identification of the first synthetic elements was established by chemical evidence. Conclusive proof of the synthesis of the first artificial element, technetium, was published in 1937 by Perrier and Segre. An essential aspect of their achievement was the prediction of the chemical properties of element 43, which had been missing from the periodic table and which was expected to have properties similar to those of manganese and rhenium. The discovery of other artificial elements, astatine and francium, was facilitated in 1939-1940 by the prediction of their chemical properties. A little more than 50 years ago, in the spring of 1940, Edwin McMillan and Philip Abelson synthesized element 93, neptunium, and confirmed its uniqueness by chemical means. On August 30, 1940, Glenn Seaborg, Arthur Wahl, and the late Joseph Kennedy began their neutron irradiations of uranium nitrate hexahydrate. A few months later they synthesized element 94, later named plutonium, by observing the alpha particles emitted from uranium oxide targets that had been bombarded with deuterons. Shortly thereafter they proved that is was the second transuranium element by establishing its unique oxidation-reduction behavior. The symposium honored the scientists and engineers whose vision and dedication led to the discovery of the transuranium elements and to the understanding of the influence of 5f electrons on their electronic structure and bonding. This volume represents a record of papers presented at the symposium

  16. Adaptation of a radiofrequency glow discharge optical emission spectrometer (RF-GD-OES) to the analysis of light elements (carbon, nitrogen, oxygen and hydrogen) in solids: glove box integration for the analysis of nuclear samples

    International Nuclear Information System (INIS)

    Hubinois, J.-C.

    2001-01-01

    The purpose of this work is to use the radiofrequency glow discharge optical emission spectrometry in order to quantitatively determine carbon, nitrogen, oxygen and hydrogen at low concentration (in the ppm range) in nuclear materials. In this study, and before the definitive contamination of the system, works are carried out on non radioactive materials (steel, pure iron, copper and titanium). As the initial apparatus could not deliver a RF power inducing a reproducible discharge and was not adapted to the analysis of light elements: 1- The radiofrequency system had to be changed, 2- The systems controlling gaseous atmospheres had to be improved in order to obtain analytical signals stemming strictly from the sample, 3- Three discharge lamps had to be tested and compared in terms of performances, 4- The system of collection of light had to be optimized. The modifications that were brought to the initial system improved intensities and stabilities of signals which allowed lower detection limits (1000 times lower for carbon). These latter are in the ppm range for carbon and about a few tens of ppm for nitrogen and oxygen in pure irons. Calibration curves were plotted in materials presenting very different sputtering rates in order to check the existence of a 'function of analytical transfer' with the purpose of palliating the lack of reference materials certified in light elements at low concentration. Transposition of this type of function to other matrices remains to be checked. Concerning hydrogen, since no usable reference material with our technique is available, certified materials in deuterium (chosen as a surrogate for hydrogen) were studied in order to exhibit the feasibility the analysis of hydrogen. Parallel to these works, results obtained by modeling a RF discharge show that the performances of the lamp can be improved and that the optical system must be strictly adapted to the glow discharge. (author) [fr

  17. SQL Server Integration Services

    CERN Document Server

    Hamilton, Bill

    2007-01-01

    SQL Server 2005 Integration Services (SSIS) lets you build high-performance data integration solutions. SSIS solutions wrap sophisticated workflows around tasks that extract, transform, and load (ETL) data from and to a wide variety of data sources. This Short Cut begins with an overview of key SSIS concepts, capabilities, standard workflow and ETL elements, the development environment, execution, deployment, and migration from Data Transformation Services (DTS). Next, you'll see how to apply the concepts you've learned through hands-on examples of common integration scenarios. Once you've

  18. ANSYS mechanical APDL for finite element analysis

    CERN Document Server

    Thompson, Mary Kathryn

    2017-01-01

    ANSYS Mechanical APDL for Finite Element Analysis provides a hands-on introduction to engineering analysis using one of the most powerful commercial general purposes finite element programs on the market. Students will find a practical and integrated approach that combines finite element theory with best practices for developing, verifying, validating and interpreting the results of finite element models, while engineering professionals will appreciate the deep insight presented on the program's structure and behavior. Additional topics covered include an introduction to commands, input files, batch processing, and other advanced features in ANSYS. The book is written in a lecture/lab style, and each topic is supported by examples, exercises and suggestions for additional readings in the program documentation. Exercises gradually increase in difficulty and complexity, helping readers quickly gain confidence to independently use the program. This provides a solid foundation on which to build, preparing readers...

  19. Monolithic microwave integrated circuit with integral array antenna

    International Nuclear Information System (INIS)

    Stockton, R.J.; Munson, R.E.

    1984-01-01

    A monolithic microwave integrated circuit including an integral array antenna. The system includes radiating elements, feed network, phasing network, active and/or passive semiconductor devices, digital logic interface circuits and a microcomputer controller simultaneously incorporated on a single substrate by means of a controlled fabrication process sequence

  20. Process to separate transuranic elements from nuclear waste

    International Nuclear Information System (INIS)

    Johnson, T.R.; Ackerman, J.P.; Tomczuk, Z.; Fischer, D.F.

    1989-01-01

    A process is described for removing transuranic elements from a waste chloride electrolytic salt containing transuranic elements in addition to rare earth and other fission product elements so the salt waste may be disposed of more easily and the valuable transuranic elements may be recovered for reuse. The salt is contacted with a cadmium-uranium alloy which selectively extracts the transuranic elements from the salt. The waste salt is generated during the reprocessing of nuclear fuel associated with the Integral Fast Reactor (IFR). 2 figs

  1. Process to separate transuranic elements from nuclear waste

    Science.gov (United States)

    Johnson, T.R.; Ackerman, J.P.; Tomczuk, Z.; Fischer, D.F.

    1989-03-21

    A process is described for removing transuranic elements from a waste chloride electrolytic salt containing transuranic elements in addition to rare earth and other fission product elements so the salt waste may be disposed of more easily and the valuable transuranic elements may be recovered for reuse. The salt is contacted with a cadmium-uranium alloy which selectively extracts the transuranic elements from the salt. The waste salt is generated during the reprocessing of nuclear fuel associated with the Integral Fast Reactor (IFR). 2 figs.

  2. Discovery of element 112

    Energy Technology Data Exchange (ETDEWEB)

    Hofmann, S. [GSI, Darmstadt (Germany)

    1996-12-31

    The new elements 110, 111, and 112 were synthesized and unambiguously identified in experiments at SHIP. Due to strong shell effects the dominant decay mode is not fission, but emission of alpha particles. Theoretical investigations predict that maximum shell effects should exist in nuclei near proton number 114 and neutron number 184. Measurements give hope that isotopes of element 114 close to the island of spherical Superheavy Elements could be produced by fusion reactions using {sup 118}Pb as target. systematic studies of the reaction cross-sections indicate that transfer of nucleons is the important process to initiate the fusion.

  3. Nuclear fuel element

    International Nuclear Information System (INIS)

    Grossman, L.N.; Levin, H.A.

    1975-01-01

    A nuclear fuel element has disposed therein an alloy having the essential components of nickel, titanium and zirconium, and the alloy reacts with water, water vapor and reactive gases at reactor ambient temperatures. The alloy is disposed in the plenum of the fuel element in the form of particles in a hollow gas permeable container having a multiplicity of openings of size smallr than the size of the particles. The container is preferably held in the spring in the plenum of the fuel element. (E.C.B.)

  4. Elemental diffusion in stars

    International Nuclear Information System (INIS)

    Michaud, Georges; Montmerle, Thierry

    1977-01-01

    This paper is dealing with the origin of the elements in the universe. The scheme of nucleosynthesis is kept to explain the stellar generation of helium, carbon, etc... from the initial hydrogen; but a nonlinear theory is then elaborated to account for the anomalous abundances which were observed. The chemical elements would diffuse throughout the outer layers of a star under the action of the opposite forces of gravitation and radiation. This theory, with completing the nucleosynthesis, would contribute to give a consistent scheme of the elemental origin and abundances [fr

  5. Development of the Fuel Element Database of PUSPATI TRIGA Reactor

    International Nuclear Information System (INIS)

    Nurhayati Ramli; Naim Syauqi Hamzah; Nurfazila Husain; Yahya Ismail; Mat Zin Mat Husin; Mohd Fairus Abd Farid

    2015-01-01

    Since June 28th, 1982, the PUSPATI TRIGA Reactor (RTP) operates safely with an accumulated energy release of about 17,200 MWhr, which corresponds to about 882 g of uranium burn-up. The reactor core has been reconfigured 15th times. Presently, there are 111 TRIGA fuel elements in the core, which 66 of the fuel elements are from the initial criticality while the rest of the fuel elements have been added to compensate the uranium consumption. As 59 % of the fuel elements are older than 30 years old, it is necessary to put the history of every fuel element in a database for easy access of the fuel element movement, inspection results history and integrity status. This paper intends to describe how the fuel element database is developed and related formulae used in determining the RTP fuel element elongation. (author)

  6. Modern industrial simulation tools: Kernel-level integration of high performance parallel processing, object-oriented numerics, and adaptive finite element analysis. Final report, July 16, 1993--September 30, 1997

    Energy Technology Data Exchange (ETDEWEB)

    Deb, M.K.; Kennon, S.R.

    1998-04-01

    A cooperative R&D effort between industry and the US government, this project, under the HPPP (High Performance Parallel Processing) initiative of the Dept. of Energy, started the investigations into parallel object-oriented (OO) numerics. The basic goal was to research and utilize the emerging technologies to create a physics-independent computational kernel for applications using adaptive finite element method. The industrial team included Computational Mechanics Co., Inc. (COMCO) of Austin, TX (as the primary contractor), Scientific Computing Associates, Inc. (SCA) of New Haven, CT, Texaco and CONVEX. Sandia National Laboratory (Albq., NM) was the technology partner from the government side. COMCO had the responsibility of the main kernel design and development, SCA had the lead in parallel solver technology and guidance on OO technologies was Sandia`s main expertise in this venture. CONVEX and Texaco supported the partnership by hardware resource and application knowledge, respectively. As such, a minimum of fifty-percent cost-sharing was provided by the industry partnership during this project. This report describes the R&D activities and provides some details about the prototype kernel and example applications.

  7. The INTEGRAL Core Observing Programme

    DEFF Research Database (Denmark)

    Winkler, C.; Gehrels, N.; Lund, Niels

    1999-01-01

    The Core Programme of the INTEGRAL mission is defined as the portion of the scientific programme covering the guaranteed time observations for the INTEGRAL Science Working Team. This paper describes the current status of the Core Programme preparations and summarizes the key elements...... of the observing programme....

  8. Implementation of a high performance parallel finite element micromagnetics package

    International Nuclear Information System (INIS)

    Scholz, W.; Suess, D.; Dittrich, R.; Schrefl, T.; Tsiantos, V.; Forster, H.; Fidler, J.

    2004-01-01

    A new high performance scalable parallel finite element micromagnetics package has been implemented. It includes solvers for static energy minimization, time integration of the Landau-Lifshitz-Gilbert equation, and the nudged elastic band method

  9. Effects of finite element formulation on optimal plate and shell structural topologies

    CSIR Research Space (South Africa)

    Long, CS

    2009-09-01

    Full Text Available , and the other is a 4-node element accounting for in-plane (drilling) rotations. Plate elements selected for evaluation include the discrete Kirchhoff quadrilateral (DKQ) element and two Mindlin–Reissner-based elements, one employing selective reduced integration...

  10. Bridge element deterioration rates.

    Science.gov (United States)

    2008-10-01

    This report describes the development of bridge element deterioration rates using the NYSDOT : bridge inspection database using Markov chains and Weibull-based approaches. It is observed : that Weibull-based approach is more reliable for developing b...

  11. 2. Transuranic elements

    International Nuclear Information System (INIS)

    Anon.

    1975-01-01

    Methods of sample collection, sample storage, sample procedures and radioanalytical procedures for transuranic elements in marine environment are reviewed and recommended. Alpha spectrometry and scintillation techniques are used for measurement of isotopic content. Separation processes for samples are described

  12. Heavy element research

    International Nuclear Information System (INIS)

    Anon.

    1976-01-01

    Heavy element research activities in metallurgy and ceramics during 1976 at Lawrence Berkeley Laboratory are reviewed. Topics include: microstructure, properties and alloy design; ceramic alloy program; high resolution and high voltage electron microscopy; and powder metallurgy

  13. Nuclear reactor fuel elements

    International Nuclear Information System (INIS)

    Hindle, E.D.

    1981-01-01

    An array of rods comprising zirconium alloy sheathed nuclear fuel pellets assembled to form a fuel element for a pressurised water reactor is claimed. The helium gas pressure within each rod differs substantially from that of its closest neighbours

  14. Nuclear reactor fuel elements

    International Nuclear Information System (INIS)

    Hindle, E.D.

    1984-01-01

    The fuel elements for a pressurised water reactor comprise arrays of rods of zirconium alloy sheathed nuclear fuel pellets. The helium gas pressure within each rod differs substantially from that of its closest neighbours

  15. Transposable elements in cancer.

    Science.gov (United States)

    Burns, Kathleen H

    2017-07-01

    Transposable elements give rise to interspersed repeats, sequences that comprise most of our genomes. These mobile DNAs have been historically underappreciated - both because they have been presumed to be unimportant, and because their high copy number and variability pose unique technical challenges. Neither impediment now seems steadfast. Interest in the human mobilome has never been greater, and methods enabling its study are maturing at a fast pace. This Review describes the activity of transposable elements in human cancers, particularly long interspersed element-1 (LINE-1). LINE-1 sequences are self-propagating, protein-coding retrotransposons, and their activity results in somatically acquired insertions in cancer genomes. Altered expression of transposable elements and animation of genomic LINE-1 sequences appear to be hallmarks of cancer, and can be responsible for driving mutations in tumorigenesis.

  16. Divergent picornavirus IRES elements

    DEFF Research Database (Denmark)

    Belsham, Graham

    2009-01-01

    Internal ribosome entry site (IRES) elements were first identified about 20 years ago within the 5' untranslated region of picornavirus RNAs. They direct a cap-independent mechanism of translation initiation on the viral RNA. Within the picornavirus family it is now known that there are four...... classes of IRES element which vary in size (450-270nt), they also have different, complex, secondary structures and distinct requirements for cellular proteins to allow them to function. This review describes the features of each class of picornavirus IRES element but focuses on the characteristics...... of the most recently described group, initially identified within the porcine teschovirus-1 RNA, which has strong similarities to the IRES elements from within the genomes of hepatitis C virus and the pestiviruses which are members of the flavivirus family. The selection of the initiation codon...

  17. An efficient finite element solution for gear dynamics

    International Nuclear Information System (INIS)

    Cooley, C G; Parker, R G; Vijayakar, S M

    2010-01-01

    A finite element formulation for the dynamic response of gear pairs is proposed. Following an established approach in lumped parameter gear dynamic models, the static solution is used as the excitation in a frequency domain solution of the finite element vibration model. The nonlinear finite element/contact mechanics formulation provides accurate calculation of the static solution and average mesh stiffness that are used in the dynamic simulation. The frequency domain finite element calculation of dynamic response compares well with numerically integrated (time domain) finite element dynamic results and previously published experimental results. Simulation time with the proposed formulation is two orders of magnitude lower than numerically integrated dynamic results. This formulation admits system level dynamic gearbox response, which may include multiple gear meshes, flexible shafts, rolling element bearings, housing structures, and other deformable components.

  18. Finite element analysis theory and application with ANSYS

    CERN Document Server

    Moaveni, Saeed

    2015-01-01

    For courses in Finite Element Analysis, offered in departments of Mechanical or Civil and Environmental Engineering. While many good textbooks cover the theory of finite element modeling, Finite Element Analysis: Theory and Application with ANSYS is the only text available that incorporates ANSYS as an integral part of its content. Moaveni presents the theory of finite element analysis, explores its application as a design/modeling tool, and explains in detail how to use ANSYS intelligently and effectively. Teaching and Learning Experience This program will provide a better teaching and learning experience-for you and your students. It will help: *Present the Theory of Finite Element Analysis: The presentation of theoretical aspects of finite element analysis is carefully designed not to overwhelm students. *Explain How to Use ANSYS Effectively: ANSYS is incorporated as an integral part of the content throughout the book. *Explore How to Use FEA as a Design/Modeling Tool: Open-ended design problems help stude...

  19. Novel porcine repetitive elements

    Directory of Open Access Journals (Sweden)

    Nonneman Dan J

    2006-12-01

    Full Text Available Abstract Background Repetitive elements comprise ~45% of mammalian genomes and are increasingly known to impact genomic function by contributing to the genomic architecture, by direct regulation of gene expression and by affecting genomic size, diversity and evolution. The ubiquity and increasingly understood importance of repetitive elements contribute to the need to identify and annotate them. We set out to identify previously uncharacterized repetitive DNA in the porcine genome. Once found, we characterized the prevalence of these repeats in other mammals. Results We discovered 27 repetitive elements in 220 BACs covering 1% of the porcine genome (Comparative Vertebrate Sequencing Initiative; CVSI. These repeats varied in length from 55 to 1059 nucleotides. To estimate copy numbers, we went to an independent source of data, the BAC-end sequences (Wellcome Trust Sanger Institute, covering approximately 15% of the porcine genome. Copy numbers in BAC-ends were less than one hundred for 6 repeat elements, between 100 and 1000 for 16 and between 1,000 and 10,000 for 5. Several of the repeat elements were found in the bovine genome and we have identified two with orthologous sites, indicating that these elements were present in their common ancestor. None of the repeat elements were found in primate, rodent or dog genomes. We were unable to identify any of the replication machinery common to active transposable elements in these newly identified repeats. Conclusion The presence of both orthologous and non-orthologous sites indicates that some sites existed prior to speciation and some were generated later. The identification of low to moderate copy number repetitive DNA that is specific to artiodactyls will be critical in the assembly of livestock genomes and studies of comparative genomics.

  20. Fuel element store

    International Nuclear Information System (INIS)

    Wieser, R.

    1987-01-01

    The spherical fuel elements are stored dry in cans. The cans themselves are stacked in parallel storage shafts, which are combined into a rectangular storage space. The storage space is made earthquake-proof by surrounding it with concrete. It consists of a ceiling assembled from several steel parts, which is connected to the floor by support elements. A cooling air ventilation station supplies the individual storage shaft and therefore the cans with cooling air via incoming and outgoing pipes. (DG) [de

  1. Intrusion detection system elements

    International Nuclear Information System (INIS)

    Eaton, M.J.; Mangan, D.L.

    1980-09-01

    This report highlights elements required for an intrusion detection system and discusses problems which can be encountered in attempting to make the elements effective. Topics discussed include: sensors, both for exterior detection and interior detection; alarm assessment systems, with the discussion focused on video assessment; and alarm reporting systems, including alarm communication systems and dislay/console considerations. Guidance on careful planning and design of a new or to-be-improved system is presented

  2. Structural elements design manual

    CERN Document Server

    Draycott, Trevor

    2012-01-01

    Gives clear explanations of the logical design sequence for structural elements. The Structural Engineer says: `The book explains, in simple terms, and with many examples, Code of Practice methods for sizing structural sections in timber, concrete,masonry and steel. It is the combination into one book of section sizing methods in each of these materials that makes this text so useful....Students will find this an essential support text to the Codes of Practice in their study of element sizing'.

  3. Atoms, molecules & elements

    CERN Document Server

    Graybill, George

    2007-01-01

    Young scientists will be thrilled to explore the invisible world of atoms, molecules and elements. Our resource provides ready-to-use information and activities for remedial students using simplified language and vocabulary. Students will label each part of the atom, learn what compounds are, and explore the patterns in the periodic table of elements to find calcium (Ca), chlorine (Cl), and helium (He) through hands-on activities.

  4. Nuclear fuel element

    International Nuclear Information System (INIS)

    Penrose, R.T.; Thompson, J.R.

    1976-01-01

    A method of protecting the cladding of a nuclear fuel element from internal attack and a nuclear fuel element for use in the core of a nuclear reactor are disclosed. The nuclear fuel element has disposed therein an additive of a barium-containing material and the barium-containing material collects reactive gases through chemical reaction or adsorption at temperatures ranging from room temperature up to fuel element plenum temperatures. The additive is located in the plenum of the fuel element and preferably in the form of particles in a hollow container having a multiplicity of gas permeable openings in one portion of the container with the openings being of a size smaller than the size of the particles. The openings permit gases and liquids entering the plenum to contact the particles. The additive is comprised of elemental barium or a barium alloy containing one or more metals in addition to barium such as aluminum, zirconium, nickel, titanium and combinations thereof. 6 claims, 3 drawing figures

  5. Finite element model for heat conduction in jointed rock masses

    International Nuclear Information System (INIS)

    Gartling, D.K.; Thomas, R.K.

    1981-01-01

    A computatonal procedure for simulating heat conduction in a fractured rock mass is proposed and illustrated in the present paper. The method makes use of a simple local model for conduction in the vicinity of a single open fracture. The distributions of fractures and fracture properties within the finite element model are based on a statistical representation of geologic field data. Fracture behavior is included in the finite element computation by locating local, discrete fractures at the element integration points

  6. On-chip multi-wavelength laser sources fabricated using generic photonic integration technology

    NARCIS (Netherlands)

    Latkowski, S.; Williams, K.A.; Bente, E.A.J.M.

    Generic photonic integration technology platforms allow for design and fabrication of large complexity application specific photonic integrated circuits. Monolithic active-passive integration on indium phosphide substrate naturally enables a reliable co-integration of optical gain elements and

  7. Fuel element transport container

    International Nuclear Information System (INIS)

    Benna, P.; Neuenfeldt, W.

    1979-01-01

    The reprocessing system includes a large number of waterfilled ponds next to each other for the intermediate storage of fuel elements from LWR's. The fuel element transport device is allocated to a middle pond. The individual ponds are separated from each other by walls, and are only accessible from the middle pond via narrow passages. The transport device includes a telescopic running rail for a trolley with a grab device for the fuel element. The running rail is supported in turn by a second trolley, which can be moved by wheels on rails. Part of the drive of the first trolley is arranged on the second one. Using this transport device, adjacent ponds can be served through the passage openings. (DG) [de

  8. Nuclear fuel element

    International Nuclear Information System (INIS)

    Hirayama, Satoshi; Kawada, Toshiyuki; Matsuzaki, Masayoshi.

    1980-01-01

    Purpose: To provide a fuel element for reducing the mechanical interactions between a fuel-cladding tube and the fuel element and for alleviating the limits of the operating conditions of a reactor. Constitution: A fuel element having mainly uranium dioxide consists of a cylindrical outer pellet and cylindrical inner pellet inserted into the outer pellet. The outer pellet contains two or more additives selected from aluminium oxide, beryllium oxide, magnesium oxide, silicon oxide, sodium oxide, phosphorus oxide, calcium oxide and iron oxide, and the inner pellet contains nuclear fuel substance solely or one additive selected from calcium oxide, silicon oxide, aluminium oxide, magnesium oxide, zirconium oxide and iron oxide. The outer pellet of the fuel thus constituted is reduced in mechanical strength and also in the mechanical interactions with the cladding tube, and the plastic fluidity of the entire pellet is prevented by the inner pellet increased in the mechanical strength. (Kamimura, M.)

  9. Creativity Management Key Elements

    Directory of Open Access Journals (Sweden)

    Rosa María Fuchs Ángeles

    2015-09-01

    Full Text Available Organizations are constantly looking towards innovation. In order to reach it they must foment creativity. This paper analyzes a series of elements considered in the organizational creativity management and proposes a model with the indispensable factors that organizations should consider to reach it. These elements are: culture and organizational environment, strategy, structure, communication, relation with customers, human resources (recruiting, training, job design, compensation, promotion, and performance evaluation, long term orientation and the organizational life cycle. Having the analysis of those elements as a basis, the indispensable pillars on management creativity are identified. The proposed model is based on 5 pillars: the alignment between strategic, culture and organizational structure, called by the authors 'Holy Trinity'; intern publicity; customer’s voice; recognition and a look towards future. Finally, the case of an innovative Peruvian enterprise is presented from the model’s perspective and the study conclusions.

  10. Fuel Element Technical Manual

    Energy Technology Data Exchange (ETDEWEB)

    Burley, H.H. [ed.

    1956-08-01

    It is the purpose of the Fuel Element Technical Manual to Provide a single document describing the fabrication processes used in the manufacture of the fuel element as well as the technical bases for these processes. The manual will be instrumental in the indoctrination of personnel new to the field and will provide a single data reference for all personnel involved in the design or manufacture of the fuel element. The material contained in this manual was assembled by members of the Engineering Department and the Manufacturing Department at the Hanford Atomic Products Operation between the dates October, 1955 and June, 1956. Arrangement of the manual. The manual is divided into six parts: Part I--introduction; Part II--technical bases; Part III--process; Part IV--plant and equipment; Part V--process control and improvement; and VI--safety.

  11. A finite element conjugate gradient FFT method for scattering

    Science.gov (United States)

    Collins, Jeffery D.; Ross, Dan; Jin, J.-M.; Chatterjee, A.; Volakis, John L.

    1991-01-01

    Validated results are presented for the new 3D body of revolution finite element boundary integral code. A Fourier series expansion of the vector electric and mangnetic fields is employed to reduce the dimensionality of the system, and the exact boundary condition is employed to terminate the finite element mesh. The mesh termination boundary is chosen such that is leads to convolutional boundary operatores of low O(n) memory demand. Improvements of this code are discussed along with the proposed formulation for a full 3D implementation of the finite element boundary integral method in conjunction with a conjugate gradiant fast Fourier transformation (CGFFT) solution.

  12. Elements of social security

    DEFF Research Database (Denmark)

    Hansen, Hans

    Elements of Social Security is a comparative study of important elements of the social security systems in Denmark (DK), Sweden (S), Finland (FIN), Austria (A), Germany (D), the Netherlands (NL), Great Britain (GB) and Canada (CAN). It should be emphasized that Germany is the former West Germany...... (Alte Länder). This is the 9th and last edition of the publication,covering income levels and rules for social security and personal taxation for 1999. Basis for the projections to 1999 income levels is the 1998 data (in some cases 1999 data)for OECD's Taxing Wages as reported by national experts....

  13. Elements of linear space

    CERN Document Server

    Amir-Moez, A R; Sneddon, I N

    1962-01-01

    Elements of Linear Space is a detailed treatment of the elements of linear spaces, including real spaces with no more than three dimensions and complex n-dimensional spaces. The geometry of conic sections and quadric surfaces is considered, along with algebraic structures, especially vector spaces and transformations. Problems drawn from various branches of geometry are given.Comprised of 12 chapters, this volume begins with an introduction to real Euclidean space, followed by a discussion on linear transformations and matrices. The addition and multiplication of transformations and matrices a

  14. Bibliography on transuranium elements

    International Nuclear Information System (INIS)

    Sood, D.D.

    1991-01-01

    A selective bibliography of prominent publications on transuranium elements is compiled. Heading papers, symposia proceedings and the textbooks are included in the bibliography. The bibliography is arranged under the headings: (1)Books, Symposia Proceedings, Reviews etc., (2)Discovery, (3)Weighable Isolation, (4)Metal Preparation, (5)Nuclear Properties, (6)Plutonium as Reactor Fuel, (7)Fuel Reprocessing, (8)Solid State Chemistry, Thermochemistry and Spectroscopy, (9)Radiation Safety, (10)Applications, and (11)Some Typical Indian Papers. Total number of references cited are 298. The bibliography, though selective, will serve as a starting point for comprehensive literature search on transuranium elements. (author)

  15. Finite elements and approximation

    CERN Document Server

    Zienkiewicz, O C

    2006-01-01

    A powerful tool for the approximate solution of differential equations, the finite element is extensively used in industry and research. This book offers students of engineering and physics a comprehensive view of the principles involved, with numerous illustrative examples and exercises.Starting with continuum boundary value problems and the need for numerical discretization, the text examines finite difference methods, weighted residual methods in the context of continuous trial functions, and piecewise defined trial functions and the finite element method. Additional topics include higher o

  16. Microlocal methods in the analysis of the boundary element method

    DEFF Research Database (Denmark)

    Pedersen, Michael

    1993-01-01

    The application of the boundary element method in numerical analysis is based upon the use of boundary integral operators stemming from multiple layer potentials. The regularity properties of these operators are vital in the development of boundary integral equations and error estimates. We show...

  17. Nondestructive examination techniques on Candu fuel elements

    International Nuclear Information System (INIS)

    Gheorghe, G.; Man, I.

    2013-01-01

    During irradiation in nuclear reactor, fuel elements undergo dimensional and structural changes, and changes of surface conditions sheath as well, which can lead to damages and even loss of integrity. Visual examination and photography of Candu fuel elements are among the non-destructive examination techniques, next to dimensional measurements that include profiling (diameter, bending, camber) and length, sheath integrity control with eddy currents, measurement of the oxide layer thickness by eddy current techniques. Unirradiated Zircaloy-4 tubes were used for calibration purposes, whereas irradiated Zircaloy-4 tubes were actually subjected to visual inspection and dimensional measurements. We present results of measurements done by eddy current techniques on Zircaloy- 4 tubes, unirradiated, but oxidized in an autoclave prior to examinations. The purpose of these nondestructive examination techniques is to determine those parameters that characterize the behavior and performance of nuclear fuel operation. (authors)

  18. Boundary element method for modelling creep behaviour

    International Nuclear Information System (INIS)

    Zarina Masood; Shah Nor Basri; Abdel Majid Hamouda; Prithvi Raj Arora

    2002-01-01

    A two dimensional initial strain direct boundary element method is proposed to numerically model the creep behaviour. The boundary of the body is discretized into quadratic element and the domain into quadratic quadrilaterals. The variables are also assumed to have a quadratic variation over the elements. The boundary integral equation is solved for each boundary node and assembled into a matrix. This matrix is solved by Gauss elimination with partial pivoting to obtain the variables on the boundary and in the interior. Due to the time-dependent nature of creep, the solution has to be derived over increments of time. Automatic time incrementation technique and backward Euler method for updating the variables are implemented to assure stability and accuracy of results. A flowchart of the solution strategy is also presented. (Author)

  19. Resonant Elements for Tunable Reflectarray Antenna Design

    Directory of Open Access Journals (Sweden)

    M. Y. Ismail

    2012-01-01

    Full Text Available This paper presents an accurate analysis of different configurations of reflectarray resonant elements that can be used for the design of passive and tunable reflectarrays. Reflection loss and bandwidth performances of these reflectarray elements have been analyzed in the X-band frequency range with the Finite Integral Method technique, and the results have been verified by the waveguide scattering parameter measurements. The results demonstrate a reduction in the phase errors offering an increased static linear phase range of 225° which allows to improve the bandwidth performance of single layer reflectarray antenna. Moreover a maximum dynamic phase range of 320° and a volume reduction of 22.15% have been demonstrated for a 10 GHz reflectarray element based on the use of rectangular patch with an embedded circular slot.

  20. Conservation and restoration of ornamental elements

    Directory of Open Access Journals (Sweden)

    Carmen Rallo Gruss

    1999-12-01

    Full Text Available Intervention on a building as complex and rich in ornamentation as the Palacio del Marqués de Dos Aguas requires special attention as regards the restoration of all the singular elements, both inside and outside, and the different finishes and furnishings. Within this methodology of integral restoration, it is worth pointing out especially the consolidation and cleaning of the emblematic alabaster portal, the restoration of the paintings and the treatment of the different collections of tiles.

  1. Integrated economics

    International Nuclear Information System (INIS)

    Bratton, T.J.

    1992-01-01

    This article offers ideas for evaluating integrated solid waste management systems through the use of a conceptual cost overview. The topics of the article include the integrated solid waste management system; making assumptions about community characteristics, waste generation rates, waste collection responsibility, integrated system components, sizing and economic life of system facilities, system implementation schedule, facility ownership, and system administration; integrated system costs; integrated system revenues; system financing; cost projections; and making decisions

  2. Elements of Social Security

    DEFF Research Database (Denmark)

    Hansen, Hans

    Elements of Social Security contains an overview of important benefit schemes in Denmark, Sweden, Finland, Austria, Germany, the Netherlands, Great Britain and Canada. The schemes are categorized according to common sets of criteria and compared. Stylized cases illustrate the impact on disposable...

  3. Elements of Social Security

    DEFF Research Database (Denmark)

    Hansen, Hans

    Elements of Social Security contains an overview of important benefit schemes in Denmark, Sweden, Finland, Germany, the Netherlands, Great Britain and Canada. The schemes are categorized according to common sets of criteria and compared. Stylized cases illustrate the impact on disposable income...

  4. Elements of Social Security

    DEFF Research Database (Denmark)

    Hansen, Hans

    Elements of Social Security contains an overview of important benefit schemes in Denmark, Sweden, Finland, Germany, Great Britain, the Netherlands and Canada. The schemes are categorized according to common sets of criteria and compared. Stylized cases illustrate the impact on disposable income...

  5. Water, the intangible element

    NARCIS (Netherlands)

    Schotting, R.J.

    2009-01-01

    Water is the key to life. No living creature can survive without water. Too much water or polluted water are serious threats to mankind. Managing this intangible element is complex, not only in wet deltaic regions but also in the (semi-)arid regions of the world. Combined efforts of the

  6. Movies and Literary Elements.

    Science.gov (United States)

    Keller, Rodney D.

    1987-01-01

    Recommends using movie clips to stimulate students' interest in reading a novel as well as to teach elements of fiction such as plot, character, setting, symbol, irony, and theme. Describes each clip and provides study questions. Includes a listing of movies made from books. (NH)

  7. Elements of Architecture

    DEFF Research Database (Denmark)

    Elements of Architecture explores new ways of engaging architecture in archaeology. It conceives of architecture both as the physical evidence of past societies and as existing beyond the physical environment, considering how people in the past have not just dwelled in buildings but have existed...

  8. Inside finite elements

    CERN Document Server

    Weiser, Martin

    2016-01-01

    All relevant implementation aspects of finite element methods are discussed in this book. The focus is on algorithms and data structures as well as on their concrete implementation. Theory is covered as far as it gives insight into the construction of algorithms. Throughout the exercises a complete FE-solver for scalar 2D problems will be implemented in Matlab/Octave.

  9. Plants' essential chemical elements

    Science.gov (United States)

    Kevin T. Smith

    2007-01-01

    Every garden center and hardware store sells fertilizer guaranteed to "feed" plants. In a strict sense, we can't feed plants. Food contains an energy source. Green plants capture solar energy and make their own food through photosynthesis! Photosynthesis and other metabolic processes require chemical elements in appropriate doses for plants to survive...

  10. Elements of relativity theory

    International Nuclear Information System (INIS)

    Lawden, D.F.

    1985-01-01

    The book on elements of relativity theory is intended for final year school students or as an early university course in mathematical physics. Special principle of relativity, lorentz transformation, velocity transformations, relativistic mechanics, and general theory of relativity, are all discussed. (U.K.)

  11. Photovoltaic radiation detector element

    International Nuclear Information System (INIS)

    Agouridis, D.C.

    1980-01-01

    A radiation detector element is formed of a body of semiconductor material, a coating on the body which forms a photovoltaic junction therewith, and a current collector consisting of narrow metallic strips, the aforesaid coating having an opening therein in the edge of which closely approaches but is spaced from the current collector strips

  12. A Novel Polygonal Finite Element Method: Virtual Node Method

    Science.gov (United States)

    Tang, X. H.; Zheng, C.; Zhang, J. H.

    2010-05-01

    Polygonal finite element method (PFEM), which can construct shape functions on polygonal elements, provides greater flexibility in mesh generation. However, the non-polynomial form of traditional PFEM, such as Wachspress method and Mean Value method, leads to inexact numerical integration. Since the integration technique for non-polynomial functions is immature. To overcome this shortcoming, a great number of integration points have to be used to obtain sufficiently exact results, which increases computational cost. In this paper, a novel polygonal finite element method is proposed and called as virtual node method (VNM). The features of present method can be list as: (1) It is a PFEM with polynomial form. Thereby, Hammer integral and Gauss integral can be naturally used to obtain exact numerical integration; (2) Shape functions of VNM satisfy all the requirements of finite element method. To test the performance of VNM, intensive numerical tests are carried out. It found that, in standard patch test, VNM can achieve significantly better results than Wachspress method and Mean Value method. Moreover, it is observed that VNM can achieve better results than triangular 3-node elements in the accuracy test.

  13. Integrated coincidence circuits

    International Nuclear Information System (INIS)

    Borejko, V.F.; Grebenyuk, V.M.; Zinov, V.G.

    1976-01-01

    The description is given of two coincidence units employing integral circuits in the VISHNYA standard. The units are distinguished for the coincidence selection element which is essentially a combination of a tunnel diode and microcircuits. The output fast response of the units is at least 90 MHz in the mode of the output signal unshaped in duration and 50 MHz minimum in the mode of the output signal shaping. The resolution time of the units is dependent upon the duration of input signals

  14. Vertical integration in the nuclear fuel cycle

    International Nuclear Information System (INIS)

    Mommsen, J.T.

    1977-01-01

    Vertical integration in the nuclear fuel cycle and its contribution to market power of integrated fuel suppliers were studied. The industry subdivision analyzed is the uranium raw materials sector. The hypotheses demonstrated are that (1) this sector of the industry is trending toward vertical integration between production of uranium raw materials and the manufacture of nuclear fuel elements, and (2) this vertical integration confers upon integrated firms a significant market advantage over non-integrated fuel manufacturers. Under microeconomic concepts the rationale for vertical integration is the pursuit of efficiency, and it is beneficial because it increases physical output and decreases price. The Market Advantage Model developed is an arithmetical statement of the relative market power (in terms of price) between non-integrated nuclear fuel manufacturers and integrated raw material/fuel suppliers, based on the concept of the ''squeeze.'' In operation, the model compares net profit and return on sales of nuclear fuel elements between the competitors, under different price and cost circumstances. The model shows that, if integrated and non-integrated competitors sell their final product at identical prices, the non-integrated manufacturer returns a net profit only 17% of the integrated firm. Also, the integrated supplier can price his product 35% below the non-integrated producer's price and still return the same net profit. Vertical integration confers a definite market advantage to the integrated supplier, and the basic source of that advantage is the cost-price differential of the raw material, uranium

  15. Finite element and boundary element applications in quantum mechanics

    International Nuclear Information System (INIS)

    Ueta, Tsuyoshi

    2003-01-01

    Although this book is one of the Oxford Texts in Applied and Engineering Mathematics, we may think of it as a physics book. It explains how to solve the problem of quantum mechanics using the finite element method (FEM) and the boundary element method (BEM). Many examples analysing actual problems are also shown. As for the ratio of the number of pages of FEM and BEM, the former occupies about 80%. This is, however, reasonable reflecting the flexibility of FEM. Although many explanations of FEM and BEM exist, most are written using special mathematical expressions and numerical computation fields. However, this book is written in the 'language of physicists' throughout. I think that it is very readable and easy to understand for physicists. In the derivation of FEM and the argument on calculation accuracy, the action integral and a variation principle are used consistently. In the numerical computation of matrices, such as simultaneous equations and eigen value problems, a description of important points is also fully given. Moreover, the practical problems which become important in the electron device design field and the condensed matter physics field are dealt with as example computations, so that this book is very practical and applicable. It is characteristic and interesting that FEM is applied to solve the Schroedinger and Poisson equations consistently, and to the solution of the Ginzburg--Landau equation in superconductivity. BEM is applied to treat electric field enhancements due to surface plasmon excitations at metallic surfaces. A number of references are cited at the end of all the chapters, and this is very helpful. The description of quantum mechanics is also made appropriately and the actual application of quantum mechanics in condensed matter physics can also be surveyed. In the appendices, the mathematical foundation, such as numerical quadrature formulae and Green's functions, is conveniently described. I recommend this book to those who need to

  16. Platinum-group elements

    Science.gov (United States)

    Zientek, Michael L.; Loferski, Patricia J.; Parks, Heather L.; Schulte, Ruth F.; Seal, Robert R.; Schulz, Klaus J.; DeYoung,, John H.; Seal, Robert R.; Bradley, Dwight C.

    2017-12-19

    The platinum-group elements (PGEs)—platinum, palladium, rhodium, ruthenium, iridium, and osmium—are metals that have similar physical and chemical properties and tend to occur together in nature. PGEs are indispensable to many industrial applications but are mined in only a few places. The availability and accessibility of PGEs could be disrupted by economic, environmental, political, and social events. The United States net import reliance as a percentage of apparent consumption is about 90 percent.PGEs have many industrial applications. They are used in catalytic converters to reduce carbon monoxide, hydrocarbon, and nitrous oxide emissions in automobile exhaust. The chemical industry requires platinum or platinum-rhodium alloys to manufacture nitric oxide, which is the raw material used to manufacture explosives, fertilizers, and nitric acid. In the petrochemical industry, platinum-supported catalysts are needed to refine crude oil and to produce aromatic compounds and high-octane gasoline. Alloys of PGEs are exceptionally hard and durable, making them the best known coating for industrial crucibles used in the manufacture of chemicals and synthetic materials. PGEs are used by the glass manufacturing industry in the production of fiberglass and flat-panel and liquid crystal displays. In the electronics industry, PGEs are used in computer hard disks, hybridized integrated circuits, and multilayer ceramic capacitors.Aside from their industrial applications, PGEs are used in such other fields as health, consumer goods, and finance. Platinum, for example, is used in medical implants, such as pacemakers, and PGEs are used in cancer-fighting drugs. Platinum alloys are an ideal choice for jewelry because of their white color, strength, and resistance to tarnish. Platinum, palladium, and rhodium in the form of coins and bars are also used as investment commodities, and various financial instruments based on the value of these PGEs are traded on major exchanges

  17. Elements of real analysis

    CERN Document Server

    Al-Gwaiz, MA

    2006-01-01

    PREFACEPRELIMINARIES Sets FunctionsREAL NUMBERSField AxiomsOrder Axioms Natural Numbers, Integers, Rational NumbersCompleteness Axiom Decimal Representation of Real Numbers Countable SetsSEQUENCESSequences and ConvergenceProperties of Convergent Sequences Monotonic SequencesThe Cauchy Criterion Subsequences Upper and Lower Limits Open and Closed Sets INFINITE SERIESBasic Properties Convergence TestsLIMIT OF A FUNCTIONLimit of a Function Basic Theorems Some Extensions of the LimitMonotonic Functions CONTINUITY Continuous Functions Combinations of Continuous Functions Continuity on an IntervalUniformContinuityCompact Sets and ContinuityDIFFERENTIATION The DerivativeTheMean Value TheoremL'Hôpital's RuleTaylor's TheoremTHE RIEMANN INTEGRALRiemann Integrability Darboux's Theorem and Riemann SumsProperties of the Integral The Fundamental Theorem of Calculus Improper IntegralsSEQUENCES AND SERIES OF FUNCTIONSSequences of FunctionsProperties of Uniform ConvergenceSeries of FunctionsPower Series LEBESGUE MEASURE Clas...

  18. Archaeal extrachromosomal genetic elements

    DEFF Research Database (Denmark)

    Wang, Haina; Peng, Nan; Shah, Shiraz Ali

    2015-01-01

    SUMMARY: Research on archaeal extrachromosomal genetic elements (ECEs) has progressed rapidly in the past decade. To date, over 60 archaeal viruses and 60 plasmids have been isolated. These archaeal viruses exhibit an exceptional diversity in morphology, with a wide array of shapes, such as spind......SUMMARY: Research on archaeal extrachromosomal genetic elements (ECEs) has progressed rapidly in the past decade. To date, over 60 archaeal viruses and 60 plasmids have been isolated. These archaeal viruses exhibit an exceptional diversity in morphology, with a wide array of shapes...... on archaeal ECEs has just started to unravel the molecular biology of these genetic entities and their interactions with archaeal hosts, it is expected to accelerate in the next decade....

  19. Nuclear fuel element

    Energy Technology Data Exchange (ETDEWEB)

    Armijo, J S; Coffing, L F

    1979-04-05

    The fuel element with circular cross-section for BWR and PWR consists of a core surrounded by a compound jacket container where there is a gap between the core and jacket during operation in the reactor. The core consists of U, Pu, Th compounds and mixtures of these. The compound jacket consists of zircaloy 2 or 4. In order to for example prevent the corrosion of the compound jacket, its inner surface has a metal barrier with smaller neutron absorbers than the jacket material in the form of a zirconium sponge. The zirconium of this metal barrier has impurities of various elements in the order of magnitude of 1000 to 5000 ppm. The oxygen content is in the range of 200 to 1200 ppm and the thickness of the metal barrier is 1-30% of the thickness of the jacket.

  20. Nuclear reactor fuel element

    International Nuclear Information System (INIS)

    D'Eye, R.W.M.; Shennan, J.V.; Ford, L.H.

    1977-01-01

    Fuel element with particles from ceramic fissionable material (e.g. uranium carbide), each one being coated with pyrolitically deposited carbon and all of them being connected at their points of contact by means of an individual crossbar. The crossbar consists of silicon carbide produced by reaction of silicon metal powder with the carbon under the influence of heat. Previously the silicon metal powder together with the particles was kneaded in a solvent and a binder (e.g. epoxy resin in methyl ethyl ketone plus setting agent) to from a pulp. The reaction temperature lies at 1750 0 C. The reaction itself may take place in a nitrogen atmosphere. There will be produced a fuel element with a high overall thermal conductivity. (DG) [de

  1. Nuclear fuel element

    International Nuclear Information System (INIS)

    1974-01-01

    A nuclear fuel element for use in the core of a nuclear reactor is disclosed. A heat conducting fission product retaining metal liner of a refractory metal is incorporated in the fuel element between the cladding and the nuclear fuel to inhibit mechanical interaction between the nuclear fuel and the cladding, to isolate fission products and nuclear fuel impurities from contacting the cladding, and to improve the axial thermal peaking gradient along the length of the fuel rod. The metal liner can be in the form of a tube or hollow cylindrical column, a foil of single or multiple layers in the shape of a hollow cylindrical column, or a coating on the internal surface of the cladding. Preferred refractory metal materials are molybdenum, tungsten, rhenium, niobium and alloys of the foregoing metals

  2. Nuclear fuel element

    International Nuclear Information System (INIS)

    Thompson, J.R.; Rowland, T.C.

    1976-01-01

    A nuclear fuel element for use in the core of a nuclear reactor is disclosed. A heat conducting, fission product retaining metal liner of a refractory metal is incorporated in the fuel element between the cladding and the nuclear fuel to inhibit mechanical interaction between the nuclear fuel and the cladding, to isolate fission products and nuclear fuel impurities from contacting the cladding and to improve the axial thermal peaking gradient along the length of the fuel rod. The metal liner can be in the form of a tube or hollow cylindrical column, a foil of single or multiple layers in the shape of a hollow cylindrical column, or a coating on the internal surface of the cladding. Preferred refractory metal materials are molybdenum, tungsten, rhenium, niobium and alloys of the foregoing metals

  3. Elements of quantum optics

    CERN Document Server

    Meystre, Pierre

    2007-01-01

    Elements of Quantum Optics gives a self-contained and broad coverage of the basic elements necessary to understand and carry out research in laser physics and quantum optics, including a review of basic quantum mechanics and pedagogical introductions to system-reservoir interactions and to second quantization. The text reveals the close connection between many seemingly unrelated topics, such as probe absorption, four-wave mixing, optical instabilities, resonance fluorescence and squeezing. It also comprises discussions of cavity quantum electrodynamics and atom optics. The 4th edition includes a new chapter on quantum entanglement and quantum information, as well as added discussions of the quantum beam splitter, electromagnetically induced transparency, slow light, and the input-output formalism needed to understand many problems in quantum optics. It also provides an expanded treatment of the minimum-coupling Hamiltonian and a simple derivation of the Gross-Pitaevskii equation, an important gateway to rese...

  4. Periodic table of elements

    International Nuclear Information System (INIS)

    Fluck, E.; Heumann, K.G.

    1985-01-01

    Following a recommendation by the International Union for Pure and Applied Chemistry (IUPAC), the groups of the periodic table shall be numbered from 1 to 18, instead of I to VIII as before. The recommendations has been approved of by the Committee on Nomenclature of the American Chemical Society. The new system abandons the distinction between main groups (a) and auxiliary groups (b), which in the past frequently has been the reason for misunderstandings between European and American chemists, due to different handling. The publishing house VCH Verlagsgesellschaft recently produced a new periodic table that shows the old and the new numbering system together at a glance, so that chemists will have time to get familiar with the new system. In addition the new periodic table represents an extensive data compilation arranged by elements. The front page lists the chemical properties of elements, the back page their physical properties. (orig./EF) [de

  5. Nuclear fuel elements

    International Nuclear Information System (INIS)

    Kawada, Toshiyuki; Hirayama, Satoshi; Yoneya, Katsutoshi.

    1980-01-01

    Purpose: To enable load-depending operation as well as moderation for the restriction of operation conditions in the present nuclear reactors, by specifying the essential ingredients and the total weight of the additives to UO 2 fuel substances. Constitution: Two or more additives selected from Al 2 O 3 , B 2 O, CaO, MgO, SiO 2 , Na 2 O and P 2 O 5 are added by the total weight of 2 - 5% to fuel substances consisting of UO 2 or a mixture of UO 2 and PuO 2 . When the mixture is sintered, the strength of the fuel elements is decreased and the fuel-cladding interactions due to the difference in the heat expansion coefficients between the ceramic fuel elements and the metal claddings are decreased to a substantially harmless degree. (Horiuchi, T.)

  6. Nuclear fuel elements

    International Nuclear Information System (INIS)

    Nakai, Keiichi

    1983-01-01

    Purpose: To decrease the tensile stresses resulted in a fuel can as well as prevent decladding of fuel pellets into the bore holes by decreasing the inner pressure within the nuclear fuel element. Constitution: A fuel can is filled with hollow fuel pellets, inserted with a spring for retaining the hollow fuel pellets with an appropriate force and, thereafter, closely sealed at the both ends with end plugs. A cylindrical body is disposed into the bore holes of the hollow fuel pellets. Since initial sealing gases and/or gaseous nuclear fission products can thus be excluded from the bore holes where the temperature is at the highest level, the inner pressure of the nuclear fuel element can be reduced to decrease the tensile strength resulted to the fuel can. Furthermore, decladding of fuel pellets into the bore holes can be prevented. (Moriyama, K.)

  7. Nuclear fuel elements

    International Nuclear Information System (INIS)

    Ainsworth, K.F.

    1979-01-01

    A nuclear fuel element is described having a cluster of nuclear fuel pins supported in parallel, spaced apart relationship by transverse cellular braces within coaxial, inner and outer sleeves, the inner sleeve being in at least two separate axial lengths, each of the transverse braces having a peripheral portion which is clamped peripherally between the ends of the axial lengths of the inner sleeve. (author)

  8. Sensor for ionizable elements

    International Nuclear Information System (INIS)

    Berkey, E.; Reed, W.A. III; Hickam, W.M.

    1977-01-01

    Sensor to detect thermally ionizable elements or molucules in air, water vapour or oxygen or to be used as alkali leak detector in vacuum systems, e.g. in the pipe system of a liquid-metal cooled FBR. The sensor consists of an filament made of thorium-containing iridium as cathode with a temperature upto 1000 0 C and an anode sheet of molybdenum, nickel or stainless steal. (ORU) [de

  9. Nuclear reactor fuel elements

    International Nuclear Information System (INIS)

    Butterfield, C.E.; Waite, E.

    1982-01-01

    A nuclear reactor fuel element comprising a column of vibration compacted fuel which is retained in consolidated condition by a thimble shaped plug. The plug is wedged into gripping engagement with the wall of the sheath by a wedge. The wedge material has a lower coefficient of expansion than the sheath material so that at reactor operating temperature the retainer can relax sufficient to accommodate thermal expansion of the column of fuel. (author)

  10. OXIDATION OF TRANSURANIC ELEMENTS

    Science.gov (United States)

    Moore, R.L.

    1959-02-17

    A method is reported for oxidizing neptunium or plutonium in the presence of cerous values without also oxidizing the cerous values. The method consists in treating an aqueous 1N nitric acid solution, containing such cerous values together with the trivalent transuranic elements, with a quantity of hydrogen peroxide stoichiometrically sufficient to oxidize the transuranic values to the hexavalent state, and digesting the solution at room temperature.

  11. Transportation of radioactive elements

    International Nuclear Information System (INIS)

    Thubert, Francis; Rentien, Guy; Jacquet, Michel

    1981-01-01

    The production and marketing of artificial radioactive elements engaged in by the 'Office des Rayonnements Ionisants' requires the use of specially designed packagings and assorted means of transport. The authors begin by describing the different kinds of products involved and the forms of packagings needed, and go on to discuss the various means of transport used, underlining the fact that, in terms of number and gravity, the incidents that have occurred to date have indeed been few and far between [fr

  12. Vented nuclear fuel element

    International Nuclear Information System (INIS)

    Oguma, M.; Hirose, Y.

    1976-01-01

    A description is given of a vented nuclear fuel element having a plenum for accumulation of fission product gases and plug means for delaying the release of the fission product gases from the plenum, the plug means comprising a first porous body wettable with a liquid metal and a second porous body non-wettable with the liquid metal, the first porous body being impregnated with the liquid metal and in contact with the liquid metal

  13. Helium the disappearing element

    CERN Document Server

    Sears, Wheeler M

    2015-01-01

    The subject of the book is helium, the element, and its use in myriad applications including MRI machines, particle accelerators, space telescopes, and of course balloons and blimps. It was at the birth of our Universe, or the Big Bang, where the majority of cosmic helium was created; and stellar helium production continues. Although helium is the second most abundant element in the Universe, it is actually quite rare here on Earth and only exists because of radioactive elements deep within the Earth. This book includes a detailed history of the discovery of helium, of the commercial industry built around it, how the helium we actually encounter is produced within the Earth, and the state of the helium industry today. The gas that most people associate with birthday party balloons is running out. “Who cares?” you might ask. Well, without helium, MRI machines could not function, rockets could not go into space, particle accelerators such as those used by CERN could not operate, fiber optic cables would not...

  14. Elements of quantum information

    International Nuclear Information System (INIS)

    Schleich, W.P.

    2007-01-01

    Elements of Quantum Information introduces the reader to the fascinating field of quantum information processing, which lives on the interface between computer science, physics, mathematics, and engineering. This interdisciplinary branch of science thrives on the use of quantum mechanics as a resource for high potential modern applications. With its wide coverage of experiments, applications, and specialized topics - all written by renowned experts - Elements of Quantum Information provides and indispensable, up-to-date account of the state of the art of this rapidly advancing field and takes the reader straight up to the frontiers of current research. The articles have first appeared as a special issue of the journal 'Fortschritte der Physik / Progress of Physics'. Since then, they have been carefully updated. The book will be an inspiring source of information and insight for anyone researching and specializing in experiments and theory of quantum information. Topics addressed in Elements of Quantum Information include - Cavity Quantum Electrodynamics - Segmented Paul Traps - Cold Atoms and Bose-Einstein Condensates in Microtraps, Optical Lattices, and on Atom Chips - Rydberg Gases - Factorization of Numbers with Physical Systems - Entanglement of Continuous Variables - NMR and Solid State Quantum Computation - Quantum Algorithms and Quantum Machines - Complexity Theory - Quantum Crytography. (orig.)

  15. Using Finite Element Method

    Directory of Open Access Journals (Sweden)

    M.H.R. Ghoreishy

    2008-02-01

    Full Text Available This research work is devoted to the footprint analysis of a steel-belted radial tyre (185/65R14 under vertical static load using finite element method. Two models have been developed in which in the first model the tread patterns were replaced by simple ribs while the second model was consisted of details of the tread blocks. Linear elastic and hyper elastic (Arruda-Boyce material models were selected to describe the mechanical behavior of the reinforcing and rubbery parts, respectively. The above two finite element models of the tyre were analyzed under inflation pressure and vertical static loads. The second model (with detailed tread patterns was analyzed with and without friction effect between tread and contact surfaces. In every stage of the analysis, the results were compared with the experimental data to confirm the accuracy and applicability of the model. Results showed that neglecting the tread pattern design not only reduces the computational cost and effort but also the differences between computed deformations do not show significant changes. However, more complicated variables such as shape and area of the footprint zone and contact pressure are affected considerably by the finite element model selected for the tread blocks. In addition, inclusion of friction even in static state changes these variables significantly.

  16. Study of Superheavy Elements

    International Nuclear Information System (INIS)

    Hofmann, Sigurd

    2007-01-01

    The nuclear shell model predicts that the next doubly magic shell-closure beyond 208 Pb is at a proton number Z = 114, 120, or 126 and at a neutron number N = 172 or 184. The outstanding aim of experimental investigations is the exploration of this region of spherical 'SuperHeavy Elements' (SHEs). Experimental methods are described, which allowed for the identification of elements produced on a cross-section level of about 1 pb. The decay data reveal that for the heaviest elements, the dominant decay mode is alpha emission, not fission. Decay properties as well as reaction cross-sections are compared with results of theoretical investigations. Finally, plans are presented for the further development of the experimental set-up and the application of new techniques, as for instance the precise mass measurement of the produced nuclei using ion traps. At increased sensitivity, the detailed exploration of the region of spherical SHEs will start, after first steps on the island were made in recent years. (Author)

  17. Probabilistic finite elements

    Science.gov (United States)

    Belytschko, Ted; Wing, Kam Liu

    1987-01-01

    In the Probabilistic Finite Element Method (PFEM), finite element methods have been efficiently combined with second-order perturbation techniques to provide an effective method for informing the designer of the range of response which is likely in a given problem. The designer must provide as input the statistical character of the input variables, such as yield strength, load magnitude, and Young's modulus, by specifying their mean values and their variances. The output then consists of the mean response and the variance in the response. Thus the designer is given a much broader picture of the predicted performance than with simply a single response curve. These methods are applicable to a wide class of problems, provided that the scale of randomness is not too large and the probabilistic density functions possess decaying tails. By incorporating the computational techniques we have developed in the past 3 years for efficiency, the probabilistic finite element methods are capable of handling large systems with many sources of uncertainties. Sample results for an elastic-plastic ten-bar structure and an elastic-plastic plane continuum with a circular hole subject to cyclic loadings with the yield stress on the random field are given.

  18. New functionalities in abundant element oxides: ubiquitous element strategy

    International Nuclear Information System (INIS)

    Hosono, Hideo; Hayashi, Katsuro; Kamiya, Toshio; Atou, Toshiyuki; Susaki, Tomofumi

    2011-01-01

    While most ceramics are composed of ubiquitous elements (the ten most abundant elements within the Earth's crust), many advanced materials are based on rare elements. A 'rare-element crisis' is approaching owing to the imbalance between the limited supply of rare elements and the increasing demand. Therefore, we propose a 'ubiquitous element strategy' for materials research, which aims to apply abundant elements in a variety of innovative applications. Creation of innovative oxide materials and devices based on conventional ceramics is one specific challenge. This review describes the concept of ubiquitous element strategy and gives some highlights of our recent research on the synthesis of electronic, thermionic and structural materials using ubiquitous elements. (topical review)

  19. Gauge Integral

    Directory of Open Access Journals (Sweden)

    Coghetto Roland

    2017-10-01

    Full Text Available Some authors have formalized the integral in the Mizar Mathematical Library (MML. The first article in a series on the Darboux/Riemann integral was written by Noboru Endou and Artur Korniłowicz: [6]. The Lebesgue integral was formalized a little later [13] and recently the integral of Riemann-Stieltjes was introduced in the MML by Keiko Narita, Kazuhisa Nakasho and Yasunari Shidama [12].

  20. Downhole Elemental Analysis with LIBS

    Science.gov (United States)

    Moreschini, Paolo; Zacny, Kris; Rickman, Doug

    2011-01-01

    In this paper we discuss a novel instrument, currently under development at Honeybee Robotics with SBIR funding from NASA. The device is designed to characterize elemental composition as a function of depth in non-terrestrial geological formations. The instrument consists of a miniaturized laser-induced breakdown spectrometer (LIBS) analyzer integrated in a 2" diameter drill string. While the drill provides subsurface access, the LIBS analyzer provides information on the elemental composition of the borehole wall. This instrument has a variety of space applications ranging from exploration of the Moon for which it was originally designed, to Mars, as well as a variety of terrestrial applications. Subsurface analysis is usually performed by sample acquisition through a drill or excavator, followed by sample preparation and subsequent sample presentation to an instrument or suite of instruments. An alternative approach consisting in bringing a miniaturized version of the instrument to the sample has many advantages over the traditional methodology, as it allows faster response, reduced probability of cross-contamination and a simplification in the sampling mechanisms. LIBS functions by focusing a high energy laser on a material inducing a plasma consisting of a small fraction of the material under analysis. Optical emission from the plasma, analyzed by a spectrometer, can be used to determine elemental composition. A triangulation sensor located in the sensor head determines the distance of the sensor from the borehole wall. An actuator modifies the position of the sensor accordingly, in order to compensate for changes due to the profile of the borehole walls. This is necessary because LIBS measurements are negatively affected by changes in the relative position of the focus of the laser with respect to the position of the sample (commonly referred to as the "lens to sample distance"). Profiling the borehole is done by adjusting the position of the sensor with a

  1. The transuranium elements: From neptunium and plutonium to element 112

    International Nuclear Information System (INIS)

    Hoffman, D.C.

    1996-01-01

    Beginning in the 1930's, both chemists and physicists became interested in synthesizing new artificial elements. The first transuranium element, Np, was synthesized in 1940. Over the past six decades, 20 transuranium elements have been produced. A review of the synthesis is given. The procedure of naming the heavy elements is also discussed. It appears feasible to produce elements 113 and 114. With the Berkeley Gas-filled Separator, it should be possible to reach the superheavy elements in the region of the spherical Z=114 shell, but with fewer neutrons than the N=184 spherical shell. 57 refs, 6 figs

  2. Elements of Making

    Science.gov (United States)

    Rodriguez, Shelly; Harron, Jason; Fletcher, Steven; Spock, Hannah

    2018-01-01

    While there is no official definition, making is generally thought of as turning ideas into products through design, invention, and building. Support is growing for integrating making into science, technology, engineering, and mathematics (STEM) education. Making can help high school students explore science concepts and phenomena, yet, lacking…

  3. VECTOR INTEGRATION

    NARCIS (Netherlands)

    Thomas, E. G. F.

    2012-01-01

    This paper deals with the theory of integration of scalar functions with respect to a measure with values in a, not necessarily locally convex, topological vector space. It focuses on the extension of such integrals from bounded measurable functions to the class of integrable functions, proving

  4. Signal integrity characterization techniques

    CERN Document Server

    Bogatin, Eric

    2009-01-01

    "Signal Integrity Characterization Techniques" addresses the gap between traditional digital and microwave curricula all while focusing on a practical and intuitive understanding of signal integrity effects within the data transmission channel. High-speed interconnects such as connectors, PCBs, cables, IC packages, and backplanes are critical elements of differential channels that must be designed using today's most powerful analysis and characterization tools.Both measurements and simulation must be done on the device under test, and both activities must yield data that correlates with each other. Most of this book focuses on real-world applications of signal integrity measurements - from backplane for design challenges to error correction techniques to jitter measurement technologies. The authors' approach wisely addresses some of these new high-speed technologies, and it also provides valuable insight into its future direction and will teach the reader valuable lessons on the industry.

  5. Towards Integrating Realities

    DEFF Research Database (Denmark)

    Henriksen, Lars Bo

    2017-01-01

    The pragmatic constructivist approach provides us with a social science theory, the theory of reality, and its associated method, the conceptualising method. A key aspect in both the theory of reality and its associated conceptualising method is on the necessity of integratingfour dimensionsof...... conceptualisation of the process of integration is itself not analysed or conceptualised to the same substantive extent as are the other elements ofthe theory of reality.The key questionaddressed here thereforebecomes: how might we betteranalyse and describe this process of integration? To address this question......, Iidentify, albeit in skeletal outline,usefulsocial theoreticalcorrespondences between Arendt’s conceptualisation of action in The Human Condition(1958) and key attributes ofthe theory of reality, which, Iclaim, couldpossibly guide an entry into the ‘how’ of this elusive integration process....

  6. Sinks as integrative elements of the anthropogenic metabolism

    Science.gov (United States)

    Kral, Ulrich; Brunner, Paul H.

    2015-04-01

    The anthropogenic metabolism is an open system requiring exchange of materials and energy between the anthroposphere and the environment. Material and energy flows are taken from nature and become utilized by men. After utilization, the materials either remain in the anthroposphere as recycling products, or they leave the anthroposphere as waste and emission flows. To accommodate these materials without jeopardizing human and environmental health, limited natural sinks are available; thus, man-made sinks have to be provided where natural sinks are missing or overloaded. The oral presentation (1) suggests a coherent definition of the term "sink", encompassing natural and man-made processes, (2) presents a framework to analyse and evaluate anthropogenic material flows to sinks, based on the tool substance flow analysis and impact assessment methodology, and (3) applies the framework in a case study approach for selected substances such as Copper and Lead in Vienna and Perfluorooctane sulfonate in Switzerland. Finally, the numeric results are aggregated in terms of a new indicator that specifies on a regional scale which fractions of anthropogenic material flows to sinks are acceptable. The following results are obtained: In Vienna, 99% of Cu flows to natural and man-made sinks are in accordance with accepted standards. However, the 0.7% of Cu entering urban soils and the 0.3% entering receiving waters surpass the acceptable level. In the case of Pb, 92% of all flows into sinks prove to be acceptable, but 8% are disposed of in local landfills with limited capacity. For PFOS, 96% of all flows into sinks are acceptable. 4% cannot be evaluated due to a lack of normative criteria, despite posing a risk for human health and the environment. The case studies corroborate the need and constraints of sinks to accommodate inevitable anthropogenic material flows.

  7. Fans: An Integral Element of the Green Learning Environment

    Science.gov (United States)

    Wolgelenter, Nina

    2011-01-01

    School districts' ongoing efforts to promote sustainability in America's education facilities are helping raise awareness of social responsibility and promoting the positive effects that greening their learning environments has on the general health and productivity of students. One institution that's taking the lead in this movement is Chandler…

  8. NASA Integrated Network COOP

    Science.gov (United States)

    Anderson, Michael L.; Wright, Nathaniel; Tai, Wallace

    2012-01-01

    Natural disasters, terrorist attacks, civil unrest, and other events have the potential of disrupting mission-essential operations in any space communications network. NASA's Space Communications and Navigation office (SCaN) is in the process of studying options for integrating the three existing NASA network elements, the Deep Space Network, the Near Earth Network, and the Space Network, into a single integrated network with common services and interfaces. The need to maintain Continuity of Operations (COOP) after a disastrous event has a direct impact on the future network design and operations concepts. The SCaN Integrated Network will provide support to a variety of user missions. The missions have diverse requirements and include anything from earth based platforms to planetary missions and rovers. It is presumed that an integrated network, with common interfaces and processes, provides an inherent advantage to COOP in that multiple elements and networks can provide cross-support in a seamless manner. The results of trade studies support this assumption but also show that centralization as a means of achieving integration can result in single points of failure that must be mitigated. The cost to provide this mitigation can be substantial. In support of this effort, the team evaluated the current approaches to COOP, developed multiple potential approaches to COOP in a future integrated network, evaluated the interdependencies of the various approaches to the various network control and operations options, and did a best value assessment of the options. The paper will describe the trade space, the study methods, and results of the study.

  9. Elements of social action

    Directory of Open Access Journals (Sweden)

    Marjanović Miloš

    2011-01-01

    Full Text Available Because of the significant analytical advantages, the author prefers social action as initial sociological concept in the relation to social phenomenon. Its basic elements are: actors, subjects and tools, needs and interests, values and norms, positions and roles. Actors set in motion and unify the rest of elements, guide to the magic triangle of sociology (movement, change, order, reaffirm actor paradigm to systemic paradigm. Subjects and tools materialize an action and its overestimate results in technological determinism or (by means of property as institutional appropriation of nature in the (unclassed historical type of society. Needs and interests are the basis of person's motivation and starting point for depth analysis of sociability. The expansion of legitimate interests circle develops techniques of normative regulation. Values and norms guide to institutional-organizational, positions to vertical and roles to horizontal structure. Values give the meaning to the action as well as to human existence, they are orientations of motivate system of personality but also basic aspect of society. As abstractions, values are latent background of norms and they tell to us what to do, and norms how to do something. Norms are specified instructions for suitable behavior Without normative order, not to be possible the satisfying of needs and the conciliation of interests. Riches, power and prestige are components of social position, and legal status is the determination of rights and obligations of the position. Roles are normative expectation of behavior. Toward kinds of sanctions roles are classified. Roles but also other elements of social action are starting point for sociological analysis of legal norms and institutes. On the other side, the observation of legal component of social actions enriches, strengths and precises sociological analysis of them.

  10. Analytical elements of mechanics

    CERN Document Server

    Kane, Thomas R

    2013-01-01

    Analytical Elements of Mechanics, Volume 1, is the first of two volumes intended for use in courses in classical mechanics. The books aim to provide students and teachers with a text consistent in content and format with the author's ideas regarding the subject matter and teaching of mechanics, and to disseminate these ideas. The book opens with a detailed exposition of vector algebra, and no prior knowledge of this subject is required. This is followed by a chapter on the topic of mass centers, which is presented as a logical extension of concepts introduced in connection with centroids. A

  11. Elements of real analysis

    CERN Document Server

    Sprecher, David A

    2010-01-01

    This classic text in introductory analysis delineates and explores the intermediate steps between the basics of calculus and the ultimate stage of mathematics: abstraction and generalization.Since many abstractions and generalizations originate with the real line, the author has made it the unifying theme of the text, constructing the real number system from the point of view of a Cauchy sequence (a step which Dr. Sprecher feels is essential to learn what the real number system is).The material covered in Elements of Real Analysis should be accessible to those who have completed a course in

  12. Nuclear reactor fuel elements

    International Nuclear Information System (INIS)

    Hindle, E. D.

    1984-01-01

    An array of rods is assembled to form a fuel element for a pressurized water reactor, the rods comprising zirconium alloy sheathed nuclear fuel pellets and containing helium. The helium gas pressure is selected for each rod so that it differs substantially from the helium gas pressure in its closest neighbors. In a preferred arrangement the rods are arranged in a square lattice and the helium gas pressure alternates between a relatively high value and a relatively low value so that each rod has as its closest neighbors up to four rods containing helium gas at the other pressure value

  13. Nuclear reactor fuel elements

    Energy Technology Data Exchange (ETDEWEB)

    Hindle, E. D.

    1984-10-16

    An array of rods is assembled to form a fuel element for a pressurized water reactor, the rods comprising zirconium alloy sheathed nuclear fuel pellets and containing helium. The helium gas pressure is selected for each rod so that it differs substantially from the helium gas pressure in its closest neighbors. In a preferred arrangement the rods are arranged in a square lattice and the helium gas pressure alternates between a relatively high value and a relatively low value so that each rod has as its closest neighbors up to four rods containing helium gas at the other pressure value.

  14. Osteoporosis and trace elements

    DEFF Research Database (Denmark)

    Aaseth, J.; Boivin, G.; Andersen, Ole

    2012-01-01

    More than 200 million people are affected by osteoporosis worldwide, as estimated by 2 million annual hip fractures and other debilitating bone fractures (vertebrae compression and Colles' fractures). Osteoporosis is a multi-factorial disease with potential contributions from genetic, endocrine...... in new bone and results in a net gain in bone mass, but may be associated with a tissue of poor quality. Aluminum induces impairment of bone formation. Gallium and cadmium suppresses bone turnover. However, exact involvements of the trace elements in osteoporosis have not yet been fully clarified...

  15. [Healthcare marketing elements].

    Science.gov (United States)

    Ameri, Cinzia; Fiorini, Fulvio

    2014-01-01

    Marketing puts its foundation on a few key concepts: need-demand, product-service, satisfaction, exchange, market, or business structure manufacturing / supply. The combination of these elements allows you to build an effective marketing strategy. Crucial in this respect is to remember the Porter matrix, which shows that for a correct analysis of the relevant market is necessary to refer to the "five forces at play", ie: customers, competitors, new entrants and substitutes threat. Another key lever for proper marketing oriented approach is the continuous and constant monitoring of the application, anticipating their dissatisfactions.

  16. Optical Finite Element Processor

    Science.gov (United States)

    Casasent, David; Taylor, Bradley K.

    1986-01-01

    A new high-accuracy optical linear algebra processor (OLAP) with many advantageous features is described. It achieves floating point accuracy, handles bipolar data by sign-magnitude representation, performs LU decomposition using only one channel, easily partitions and considers data flow. A new application (finite element (FE) structural analysis) for OLAPs is introduced and the results of a case study presented. Error sources in encoded OLAPs are addressed for the first time. Their modeling and simulation are discussed and quantitative data are presented. Dominant error sources and the effects of composite error sources are analyzed.

  17. Elements of energy conversion

    CERN Document Server

    Russell, Charles R

    2013-01-01

    Elements of Energy Conversion brings together scattered information on the subject of energy conversion and presents it in terms of the fundamental thermodynamics that apply to energy conversion by any process. Emphasis is given to the development of the theory of heat engines because these are and will remain most important power sources. Descriptive material is then presented to provide elementary information on all important energy conversion devices. The book contains 10 chapters and opens with a discussion of forms of energy, energy sources and storage, and energy conversion. This is foll

  18. Os ensinos da educação para a saúde na prevenção de HIV-Aids: subsídios teóricos para a construção de uma práxis integral Lessons from health education for HIV/Aids prevention: theoretical elements for the construction of a new integrated praxis

    Directory of Open Access Journals (Sweden)

    Edgar Merchán-Hamann

    1999-01-01

    Full Text Available Foi constatado um contraste entre as práticas de educação em saúde e a reflexão teórica sobre as mesmas (modelos. Enquanto as primeiras têm tido um desenvolvimento considerável em estratégias, metodologias e modalidades, a segunda permanece reducionista, fragmentadora e atrelada à psicologia comportamentalista. Apontam-se como maiores problemas de tais modelos o individualismo, a alteridade nas relações educador-educando, a passividade do educando, a falta de contextualidade macrossocial e cultural, bem como a ênfase em comportamentos. Propõe-se uma práxis baseada em dez níveis de integração de dimensões múltiplas do ser humano: 1 a complexidade dos objetos requer interdisciplinaridade; 2 concepção holística; 3 integração das duas dimensões de percepção (vivência e expressão (ação em uma linguagem integral; 4 inserção da prática em contextos reais; 5 constatação do continuum indivíduo-coletivo; 6 educação simétrica, dialogal e ativa; 7 integração de processos intelectuais-cognitivos e afetivo-volitivos; 8 visão de riscos como vulnerabilidades de coletivos capazes de iniciativa e organização; 9 visão lúdica que inclui o real imaginado nos jogos de papéis; 10 contemplação do outro e da diversidade. Enfatiza-se o aspecto político da educação como promotora de cidadania e de mudança social.There is an evident contrast between health education practices and theoretical reflection concerning them as models. Health education practices have undergone considerable development in terms of strategies, methods, and modalities, while theoretical models have remained deficient, reductionist, fragmentary, and focused on behavior rather than social practices. Major problems include individualism, asymmetrical "teacher-student" relationships, students as passive objects of practices, lack of social and cultural contextualism, and excessive focus on factual behavior. We propose a praxis based on ten levels of

  19. Project Integration Architecture

    Science.gov (United States)

    Jones, William Henry

    2008-01-01

    The Project Integration Architecture (PIA) is a distributed, object-oriented, conceptual, software framework for the generation, organization, publication, integration, and consumption of all information involved in any complex technological process in a manner that is intelligible to both computers and humans. In the development of PIA, it was recognized that in order to provide a single computational environment in which all information associated with any given complex technological process could be viewed, reviewed, manipulated, and shared, it is necessary to formulate all the elements of such a process on the most fundamental level. In this formulation, any such element is regarded as being composed of any or all of three parts: input information, some transformation of that input information, and some useful output information. Another fundamental principle of PIA is the assumption that no consumer of information, whether human or computer, can be assumed to have any useful foreknowledge of an element presented to it. Consequently, a PIA-compliant computing system is required to be ready to respond to any questions, posed by the consumer, concerning the nature of the proffered element. In colloquial terms, a PIA-compliant system must be prepared to provide all the information needed to place the element in context. To satisfy this requirement, PIA extends the previously established object-oriented- programming concept of self-revelation and applies it on a grand scale. To enable pervasive use of self-revelation, PIA exploits another previously established object-oriented-programming concept - that of semantic infusion through class derivation. By means of self-revelation and semantic infusion through class derivation, a consumer of information can inquire about the contents of all information entities (e.g., databases and software) and can interact appropriately with those entities. Other key features of PIA are listed.

  20. QUANTITATIVE СHARACTERISTICS OF COMPLEMENTARY INTEGRATED HEALTH CARE SYSTEM AND INTEGRATED MEDICATION MANAGEMENT INFORMATION SYSTEM

    Directory of Open Access Journals (Sweden)

    L. Yu. Babintseva

    2015-05-01

    i mportant elements of state regulation of the pharmaceutical sector health. For the first time creation of two information systems: integrated medication management infor mation system and integrated health care system in an integrated medical infor mation area, operating based on th e principle of complementarity was justified. Global and technological coefficients of these systems’ functioning were introduced.

  1. Endogenous viral elements in animal genomes.

    Directory of Open Access Journals (Sweden)

    Aris Katzourakis

    2010-11-01

    Full Text Available Integration into the nuclear genome of germ line cells can lead to vertical inheritance of retroviral genes as host alleles. For other viruses, germ line integration has only rarely been documented. Nonetheless, we identified endogenous viral elements (EVEs derived from ten non-retroviral families by systematic in silico screening of animal genomes, including the first endogenous representatives of double-stranded RNA, reverse-transcribing DNA, and segmented RNA viruses, and the first endogenous DNA viruses in mammalian genomes. Phylogenetic and genomic analysis of EVEs across multiple host species revealed novel information about the origin and evolution of diverse virus groups. Furthermore, several of the elements identified here encode intact open reading frames or are expressed as mRNA. For one element in the primate lineage, we provide statistically robust evidence for exaptation. Our findings establish that genetic material derived from all known viral genome types and replication strategies can enter the animal germ line, greatly broadening the scope of paleovirological studies and indicating a more significant evolutionary role for gene flow from virus to animal genomes than has previously been recognized.

  2. FY 1991 report on the results of the development of the entrained bed coal gasification power plant. Part 1. Element study/investigational study of technology/study of the integrated coal gasification combined cycle power system; 1991 nendo seika hokokusho. Funryusho sekitan gaska hatsuden plant kaihatsu - Sono 1. Youso kenkyu hen, gijutsu chosa hen, sekitan gaska fukugo hatsuden system kento hen

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1993-01-01

    For the purpose of establishing the technology of integrated coal gasification combined cycle power generation, the following were conducted: element study of a 200t/d entrained bed coal gasification pilot plant, survey of technology of the coal gasification power generation, study of the practical scale IGCC, etc. The FY 1991 results were summarized. In the gasification test using 2t/d furnace equipment, evaluation test on the test coal for pilot plant was made. In the study of gas turbine combustor for demonstration machine use, measuring duct was fabricated for measurement of combustion gas temperature/pressure, etc. In the simulational study of the total system of combined cycle power generation, review/modification of part of the simulation model and detailing of the model were conducted by comparison with the data on pilot plant operation. In the technology study, joint technology conferences were held for discussions between Japan and Australia, Japan and the U.S., and Japan and Canada. As to the practical scale IGCC, the initially planned output capacity and thermal efficiency were studied based on the knowledge/information obtained through the R and D on the 200t/d pilot plant. (NEDO)

  3. Nuclear fuel element

    International Nuclear Information System (INIS)

    Iwano, Yoshihiko.

    1993-01-01

    Microfine cracks having a depth of less than 10% of a pipe thickness are disposed radially from a central axis each at an interval of less than 100 micron over the entire inner circumferential surface of a zirconium alloy fuel cladding tube. For manufacturing such a nuclear fuel element, the inside of the cladding tube is at first filled with an electrolyte solution of potassium chloride. Then, electrolysis is conducted using the cladding tube as an anode and the electrolyte solution as a cathode, and the inner surface of the cladding tube with a zirconium dioxide layer having a predetermined thickness. Subsequently, the cladding tube is laid on a smooth steel plate and lightly compressed by other smooth steel plate to form microfine cracks in the zirconium dioxide layer on the inner surface of the cladding tube. Such a compressing operation is continuously applied to the cladding tube while rotating the cladding tube. This can inhibit progress of cracks on the inner surface of the cladding tube, thereby enabling to prevent failure of the cladding tube even if a pellet/cladding tube mechanical interaction is applied. Accordingly, reliability of the nuclear fuel elements is improved. (I.N.)

  4. Heavy-element nucleosynthesis

    International Nuclear Information System (INIS)

    Mathews, G.J.

    1990-01-01

    New measurements and theoretical studies of nuclear properties, together with new astronomical data on the growth of heavy-element abundances during the early history of the Galaxy, now provide a clearer picture of where in nature the elements heavier than iron are produced by rapid (r-process) and show (s-process) neutron capture reactions. The nuclear data suggest that the r-process involves a high-neutron-density beta-flow equilibrium environment and that the s-process may have occurred at a temperature and neutron density consistent with a 13 C(α,n) 16 0 neutron source. The astronomical data, when compared with simple galactic chemical evolution modes, suggests that the r-process is associated with type II supernovae and that the neutron source must be manufactured by the star. Low-mass type II supernovae are proposed as the most important contributors to the r-process. A 13 C neutron source in intermediate-mass stars is proposed for the s-process. 64 refs., 7 figs

  5. Improved nuclear fuel element

    International Nuclear Information System (INIS)

    1980-01-01

    The invention is of a nuclear fuel element which comprises a central core of a body of nuclear fuel material selected from the group consisting of compounds of uranium, plutonium, thorium and mixtures thereof, and an elongated composite cladding container comprising a zirconium alloy tube containing constituents other than zirconium in an amount greater than about 5000 parts per million by weight and an undeformed metal barrier of moderate purity zirconium bonded to the inside surface of the alloy tube. The container encloses the core so as to leave a gap between the container and the core during use in a nuclear reactor. The metal barrier is of moderate purity zirconium with an impurity level on a weight basis of at least 1000ppm and less than 5000ppm. Impurity levels of specific elements are given. Variations of the invention are also specified. The composite cladding reduces chemical interaction, minimizes localized stress and strain corrosion and reduces the likelihood of a splitting failure in the zirconium alloy tube. Other benefits are claimed. (U.K.)

  6. NATIONAL INTEGRATION AND SOCIAL STABILITY – THE ...

    African Journals Online (AJOL)

    NGOZI

    In a multi-lingual and multi-ethnicity society, integration and social stability are pivotal issues. Given the .... natives to acquire western education which is central to national development. ... group element reflects a common national background ...

  7. Integrated Medical Model – Chest Injury Model

    Data.gov (United States)

    National Aeronautics and Space Administration — The Exploration Medical Capability (ExMC) Element of NASA's Human Research Program (HRP) developed the Integrated Medical Model (IMM) to forecast the resources...

  8. Application of finite element numerical technique to nuclear reactor geometries

    Energy Technology Data Exchange (ETDEWEB)

    Rouai, N M [Nuclear engineering department faculty of engineering Al-fateh universty, Tripoli (Libyan Arab Jamahiriya)

    1995-10-01

    Determination of the temperature distribution in nuclear elements is of utmost importance to ensure that the temperature stays within safe limits during reactor operation. This paper discusses the use of Finite element numerical technique (FE) for the solution of the two dimensional heat conduction equation in geometries related to nuclear reactor cores. The FE solution stats with variational calculus which considers transforming the heat conduction equation into an integral equation I(O) and seeks a function that minimizes this integral and hence gives the solution to the heat conduction equation. In this paper FE theory as applied to heat conduction is briefly outlined and a 2-D program is used to apply the theory to simple shapes and to two gas cooled reactor fuel elements. Good results are obtained for both cases with reasonable number of elements. 7 figs.

  9. Application of finite element numerical technique to nuclear reactor geometries

    International Nuclear Information System (INIS)

    Rouai, N. M.

    1995-01-01

    Determination of the temperature distribution in nuclear elements is of utmost importance to ensure that the temperature stays within safe limits during reactor operation. This paper discusses the use of Finite element numerical technique (FE) for the solution of the two dimensional heat conduction equation in geometries related to nuclear reactor cores. The FE solution stats with variational calculus which considers transforming the heat conduction equation into an integral equation I(O) and seeks a function that minimizes this integral and hence gives the solution to the heat conduction equation. In this paper FE theory as applied to heat conduction is briefly outlined and a 2-D program is used to apply the theory to simple shapes and to two gas cooled reactor fuel elements. Good results are obtained for both cases with reasonable number of elements. 7 figs

  10. NIH Common Data Elements Repository

    Data.gov (United States)

    U.S. Department of Health & Human Services — The NIH Common Data Elements (CDE) Repository has been designed to provide access to structured human and machine-readable definitions of data elements that have...

  11. Joining elements of silicon carbide

    International Nuclear Information System (INIS)

    Olson, B.A.

    1979-01-01

    A method of joining together at least two silicon carbide elements (e.g.in forming a heat exchanger) is described, comprising subjecting to sufficiently non-oxidizing atmosphere and sufficiently high temperature, material placed in space between the elements. The material consists of silicon carbide particles, carbon and/or a precursor of carbon, and silicon, such that it forms a joint joining together at least two silicon carbide elements. At least one of the elements may contain silicon. (author)

  12. Integrated marketing communications in sport organizations

    Directory of Open Access Journals (Sweden)

    Gašović Milan

    2011-01-01

    Full Text Available Integrated marketing communications represent the unification of organization's marketing and communication activities. Sports organizations have the emphasized need for effective communication with their environment (the public, the media, advertisers, sponsors, and other subjects interested in their offer. Elements of the integrated marketing communications are: advertising, personal selling, sales promotion, publicity, public relations, direct marketing, Internet communications etc. Each of these elements has some specifics which marketing specialists in sports organizations need to understand.

  13. Interorganisational Integration

    DEFF Research Database (Denmark)

    Lyngsø, Anne Marie; Godtfredsen, Nina Skavlan; Frølich, Anne

    2016-01-01

    INTRODUCTION: Despite many initiatives to improve coordination of patient pathways and intersectoral cooperation, Danish health care is still fragmented, lacking intra- and interorganisational integration. This study explores barriers to and facilitators of interorganisational integration...... at a university hospital in the Capital Region of Denmark. RESULTS AND DISCUSSION: Our results can be grouped into five influencing areas for interorganisational integration: communication/information transfer, committed leadership, patient engagement, the role and competencies of the general practitioner...... and organisational culture. Proposed solutions to barriers in each area hold the potential to improve care integration as experienced by individuals responsible for supporting and facilitating it. Barriers and facilitators to integrating care relate to clinical, professional, functional and normative integration...

  14. Vertical integration

    International Nuclear Information System (INIS)

    Antill, N.

    1999-01-01

    This paper focuses on the trend in international energy companies towards vertical integration in the gas chain from wellhead to power generation, horizontal integration in refining and marketing businesses, and the search for larger projects with lower upstream costs. The shape of the petroleum industry in the next millennium, the creation of super-major oil companies, and the relationship between size and risk are discussed. The dynamics of vertical integration, present events and future developments are considered. (UK)

  15. Trace element emissions from coal

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-09-15

    Trace elements are emitted during coal combustion. The quantity, in general, depends on the physical and chemical properties of the element itself, the concentration of the element in the coal, the combustion conditions and the type of particulate control device used, and its collection efficiency as a function of particle size. Some trace elements become concentrated in certain particle streams following combustion such as bottom ash, fly ash, and flue gas particulate matter, while others do not. Various classification schemes have been developed to describe this partitioning behaviour. These classification schemes generally distinguish between: Class 1: elements that are approximately equally concentrated in the fly ash and bottom ash, or show little or no fine particle enrichment, examples include Mn, Be, Co and Cr; Class 2: elements that are enriched in the fly ash relative to bottom ash, or show increasing enrichment with decreasing particle size, examples include As, Cd, Pb and Sb; Class 3: elements which are emitted in the gas phase (primarily Hg (not discussed in this review), and in some cases, Se). Control of class 1 trace elements is directly related to control of total particulate matter emissions, while control of the class 2 elements depends on collection of fine particulates. Due to the variability in particulate control device efficiencies, emission rates of these elements can vary substantially. The volatility of class 3 elements means that particulate controls have only a limited impact on the emissions of these elements.

  16. REACTOR FUEL ELEMENTS TESTING CONTAINER

    Science.gov (United States)

    Whitham, G.K.; Smith, R.R.

    1963-01-15

    This patent shows a method for detecting leaks in jacketed fuel elements. The element is placed in a sealed tank within a nuclear reactor, and, while the reactor operates, the element is sparged with gas. The gas is then led outside the reactor and monitored for radioactive Xe or Kr. (AEC)

  17. A computer program for structural analysis of fuel elements

    International Nuclear Information System (INIS)

    Hayashi, I.M.V.; Perrotta, J.A.

    1988-01-01

    It's presented the code ELCOM for the matrix analysis of tubular structures coupled by rigid spacers, typical of PWR's fuel elements. The code ELCOM makes a static structural analysis, where the displacements and internal forces are obtained for each structure at the joints with the spacers, and also, the natural frequencies and vibrational modes of an equivalent integrated structure are obtained. The ELCOM result is compared to a PWR fuel element structural analysis obtained in published paper. (author) [pt

  18. Finite elements for the thermomechanical calculation of massive structures

    International Nuclear Information System (INIS)

    Argyris, J.H.; Szimmat, J.; Willam, K.J.

    1978-01-01

    The paper examines the fine element analysis of thermal stress and deformation problems in massive structures. To this end compatible idealizations are utilized for heat conduction and static analysis in order to minimize the data transfer. For transient behaviour due to unsteady heat flow and/or inelastics material processes the two computational parts are interwoven in form of an integrated software package for finite element analysis of thermomechanical problems in space and time. (orig.) [de

  19. DISSOLVED CONCENTRATION LIMITS OF RADIOACTIVE ELEMENTS

    Energy Technology Data Exchange (ETDEWEB)

    NA

    2004-11-22

    The purpose of this study is to evaluate dissolved concentration limits (also referred to as solubility limits) of elements with radioactive isotopes under probable repository conditions, based on geochemical modeling calculations using geochemical modeling tools, thermodynamic databases, field measurements, and laboratory experiments. The scope of this modeling activity is to predict dissolved concentrations or solubility limits for 14 elements with radioactive isotopes (actinium, americium, carbon, cesium, iodine, lead, neptunium, plutonium, protactinium, radium, strontium, technetium, thorium, and uranium) important to calculated dose. Model outputs for uranium, plutonium, neptunium, thorium, americium, and protactinium are in the form of tabulated functions with pH and log (line integral) CO{sub 2} as independent variables, plus one or more uncertainty terms. The solubility limits for the remaining elements are either in the form of distributions or single values. The output data from this report are fundamental inputs for Total System Performance Assessment for the License Application (TSPA-LA) to determine the estimated release of these elements from waste packages and the engineered barrier system. Consistent modeling approaches and environmental conditions were used to develop solubility models for all of the actinides. These models cover broad ranges of environmental conditions so that they are applicable to both waste packages and the invert. Uncertainties from thermodynamic data, water chemistry, temperature variation, and activity coefficients have been quantified or otherwise addressed.

  20. Integral equations

    CERN Document Server

    Moiseiwitsch, B L

    2005-01-01

    Two distinct but related approaches hold the solutions to many mathematical problems--the forms of expression known as differential and integral equations. The method employed by the integral equation approach specifically includes the boundary conditions, which confers a valuable advantage. In addition, the integral equation approach leads naturally to the solution of the problem--under suitable conditions--in the form of an infinite series.Geared toward upper-level undergraduate students, this text focuses chiefly upon linear integral equations. It begins with a straightforward account, acco

  1. Accelerator vacuum system elements

    International Nuclear Information System (INIS)

    Sivokon', V.V.; Kobets, A.F.; Shvetsov, V.A.; Sivokon', L.V.

    1980-01-01

    Some elements of vacuum systems are investigated. Considerable attention has been given to the investigation into peculiarities in pumping out of a ionoguide for transportation of an accelerated charged particles beam the spread of which often attains a considerable length. The number of pumps over the ionoguide length is experimentally determined. It is shown that as a result of ionoguide warm-up the pumping out time is considerably reduced maximum permissible pressure is decreased by two orders and lesser rate of pump pumping out is required. The investigations have shown that when operating the ionoguide there is no necessity in setting up seals between the ionoguide and magnetodischarged pump. The causes of the phenomenon in which the pressure near the pump is greater than in the end of the ionoguide, are impurities carried in by the pump into the ionoguide volume and the pumping out capacity of the pressure converter

  2. Ucla, escuela elemental

    Directory of Open Access Journals (Sweden)

    Neutra, Richard J.

    1962-03-01

    Full Text Available La Escuela Elemental de Preparación de la Universidad de California, en Los Angeles, está dedicada a la educación e investigación y preparación del profesorado de la infancia. Se ha construido en un paraje maravilloso, de frondosa vegetación, frente a un terreno bastante quebrado, circunstancia que presta mayor encanto al conjunto, construido con gran pericia y adaptación al paisaje a base de una dominante horizontalidad, con materiales sencillos (ladrillos, hierro y madera y gran comunicación con la naturaleza mediante grandes cristaleras correderas que ensanchan las clases y las suplementan hacia el jardín de acuerdo con las nuevas normas y prácticas docentes.

  3. Improved nuclear fuel element

    International Nuclear Information System (INIS)

    1974-01-01

    A nuclear fuel element for use in the core of a nuclear reactor is disclosed and has a metal liner disposed between the cladding and the nuclear fuel material and a high lubricity material in the form of a coating disposed between the liner and the cladding. The liner preferably has a thickness greater than the longest fission product recoil distance and is composed of a low neutron capture cross-section material. The liner is preferably composed of zirconium, an alloy of zirconium, niobium or an alloy of niobium. The liner serves as a preferential reaction site for volatile impurities and fission products and protects the cladding from contact and reaction with such impurities and fission products. The high lubricity material acts as an interface between the liner and the cladding and reduces localized stresses on the cladding due to fuel expansion and cracking of the fuel

  4. Probabilistic fracture finite elements

    Science.gov (United States)

    Liu, W. K.; Belytschko, T.; Lua, Y. J.

    1991-05-01

    The Probabilistic Fracture Mechanics (PFM) is a promising method for estimating the fatigue life and inspection cycles for mechanical and structural components. The Probability Finite Element Method (PFEM), which is based on second moment analysis, has proved to be a promising, practical approach to handle problems with uncertainties. As the PFEM provides a powerful computational tool to determine first and second moment of random parameters, the second moment reliability method can be easily combined with PFEM to obtain measures of the reliability of the structural system. The method is also being applied to fatigue crack growth. Uncertainties in the material properties of advanced materials such as polycrystalline alloys, ceramics, and composites are commonly observed from experimental tests. This is mainly attributed to intrinsic microcracks, which are randomly distributed as a result of the applied load and the residual stress.

  5. Nuclear fuel elements

    International Nuclear Information System (INIS)

    Obara, Hiroshi.

    1981-01-01

    Purpose: To suppress iodine release thereby prevent stress corrosion cracks in fuel cans by dispersing ferrous oxide at the outer periphery of sintered uranium dioxide pellets filled and sealed within zirconium alloy fuel cans of fuel elements. Constitution: Sintered uranium dioxide pellets to be filled and sealed within a zirconium alloy fuel can are prepared either by mixing ferric oxide powder in uranium dioxide powder, sintering and then reducing at low temperature or by mixing iron powder in uranium dioxide powder, sintering and then oxidizing at low temperature. In this way, ferrous oxide is dispersed on the outer periphery of the sintered uranium dioxide pellets to convert corrosive fission products iodine into iron iodide, whereby the iodine release is suppressed and the stress corrosion cracks can be prevented in the fuel can. (Moriyama, K.)

  6. Nuclear fuel element

    International Nuclear Information System (INIS)

    Hirama, H.

    1978-01-01

    A nuclear fuel element comprises an elongated tube having upper and lower end plugs fixed to both ends thereof and nuclear fuel pellets contained within the tube. The fuel pellets are held against the lower end plug by a spring which is supported by a setting structure. The setting structure is maintained at a proper position at the middle of the tube by a wedge effect caused by spring force exerted by the spring against a set of balls coacting with a tapered member of the setting structure thereby wedging the balls against the inner wall of the tube, and the setting structure is moved free by pushing with a push bar against the spring force so as to release the wedge effect

  7. Finite element modelling

    International Nuclear Information System (INIS)

    Tonks, M.R.; Williamson, R.; Masson, R.

    2015-01-01

    The Finite Element Method (FEM) is a numerical technique for finding approximate solutions to boundary value problems. While FEM is commonly used to solve solid mechanics equations, it can be applied to a large range of BVPs from many different fields. FEM has been used for reactor fuels modelling for many years. It is most often used for fuel performance modelling at the pellet and pin scale, however, it has also been used to investigate properties of the fuel material, such as thermal conductivity and fission gas release. Recently, the United Stated Department Nuclear Energy Advanced Modelling and Simulation Program has begun using FEM as the basis of the MOOSE-BISON-MARMOT Project that is developing a multi-dimensional, multi-physics fuel performance capability that is massively parallel and will use multi-scale material models to provide a truly predictive modelling capability. (authors)

  8. Heavy-element research

    International Nuclear Information System (INIS)

    Anon.

    1975-01-01

    The status is reported of studies on the solid-state chemistry of the actinides and lanthanides, spectroscopy of actinide compounds, and dynamic chemical description of actinide elements in solution. Phase studies were done on Rb 2 UO 4 , K 2 UO 4 , Li 2 UO 4 , and Es 2 U 2 O 7 . The lithium neptunate (VI) system was investigated and the existence of Li 2 NpO 4 was established. In oxidation-reduction studies it was shown that Am(III) can be electrolytically oxidized to Am(IV) in strong H 3 PO 4 , but Cf(III) and Pr(III) do not oxidize. The low-temperature absorption spectrum of thin films of NpBr 3 was investigated. (U.S.)

  9. ELEMENTAL FORMS OF HOSPITALITY

    Directory of Open Access Journals (Sweden)

    Maximiliano Emanuel Korstanje

    2010-11-01

    Full Text Available Modern studies emphasized on the needs of researching the hospitality as relevant aspects of tourism and hospitality fields. Anyway, these approaches are inextricably intertwined to the industry of tourism and do not take seriously the anthropological and sociological roots of hospitality. In fact, the hotel seems to be a partial sphere of hospitality at all. Under this context, the present paper explores the issue of hospitality enrooted in the political and economic indo-European principle of free-transit which is associated to a much broader origin.  Starting from the premise etymologically hostel and hospital share similar origins, we follow the contributions of J Derrida to determine the elements that formed the hospitality up to date.

  10. Photo-switching element

    Energy Technology Data Exchange (ETDEWEB)

    Masaki, Yuichi

    1987-10-31

    Photo-input MOS transistor (Photo-switching element) cannot give enough ON/OFF ratio but requires an auxiliary condenser for a certain type of application. In addition, PN junction of amorphous silicon is not practical because it gives high leak current resulting in low electromotive force. In this invention, a solar cell was constructed with a lower electrode consisting of a transparent electro-conducting film, a photosensitive part consisting of an amorphous Si layer of p-i-n layer construction, and an upper metal electrode consisting of Cr or Nichrome, and a thin film transistor was placed on the solar cell, and further the upper metal electrode was co-used as a gate electrode of the thin film transistor; this set-up of this invention enabled to attain an efficient photo-electric conversion of the incident light, high electromotive force of the solar cell, and the transistor with high ON/OFF ratio. (3 figs)

  11. SXT/R391 ICE elements encode a novel ‘trap-door’ strategy for mobile element escape

    Directory of Open Access Journals (Sweden)

    Michael P Ryan

    2016-05-01

    Full Text Available Integrative Conjugative Elements (ICEs are a class of bacterial mobile elements that have the ability to mediate their own integration, excision and transfer from one host genome to another by a mechanism of site-specific recombination, self-circularisation and conjugative transfer. Members of the SXT/R391 ICE family of enterobacterial mobile genetic elements display an unusual UV-inducible sensitisation function which results in stress induced killing of bacterial cells harbouring the ICE. This sensitisation has been shown to be associated with a stress induced overexpression of a mobile element encoded conjugative transfer gene, orf43, a traV homolog. This results in cell lysis and release of a circular form of the ICE. Induction of this novel system may allow transfer of an ICE, enhancing its survival potential under conditions not conducive to conjugative transfer.

  12. Integration of solar energy in buildings

    Energy Technology Data Exchange (ETDEWEB)

    Peippo, K.; Lund, P.; Mennola, T.; Vartiainen, E. [Helsinki Univ. of Technology, Otaniemi (Finland). Dept. of Engineering Physics and Mathematics; Leppaenen, J.; Rasinkoski, A.; Spiers, D.; Eenilae, P. [Neste Advanced Power Systems (Finland)

    1998-12-31

    New photovoltaic building elements were developed and the uses of various solar technologies in buildings were optimised with computational design tools. The novel amorphous silicon photovoltaic elements allow for economic integration of photovoltaics in large facades. The cost of grid-connected systems may be reduced by approximately 20 % through the advanced design approaches developed. (orig.)

  13. An integral transform related to quantization

    International Nuclear Information System (INIS)

    Daubechies, I.; Grossmann, A.

    1978-08-01

    The authors study in a coordinate-free way the integral transform relating a function on phase space to the matrix elements of the corresponding quantum mechanical operator between coherent states. The items discussed include: inversion (given by the same kernel), bounds, matrix elements between eigenstates of harmonic oscillators, and classical functions corresponding to permutation operators. (author)

  14. Finite element analysis of ARPS structures

    International Nuclear Information System (INIS)

    Ruhkamp, J.D.; McDougal, J.R.; Kramer, D.P.

    1998-01-01

    Algor finite element software was used to determine the stresses and deflections in the metallic walls of Advanced Radioisotope Power Systems (ARPS) designs. The preliminary design review of these systems often neglects the structural integrity of the design which can effect fabrication and the end use of the design. Before finite element analysis (FEA) was run on the canister walls of the thermophotovoltaic (TPV) generator, hand calculations were used to approximate the stresses and deflections in a flat plate. These results compared favorably to the FEA results of a similar size flat plate. The AMTEC (Alkali Metal Thermal-to-Electric Conversion) cells were analyzed by FEA and the results compared to two cells that were mechanically tested. The mechanically tested cells buckled in the thin sections, one at the top and one in the lower section. The FEA predicted similar stress and shape results but the critical buckling load was found to be very shape dependent

  15. Integration of Andragogy into Preceptorship

    Science.gov (United States)

    Leigh, Katherine; Whitted, Kelli; Hamilton, Bernita

    2015-01-01

    Return of registered nurses to school dictates that mobility programs integrate principles and design elements of adult learning theory. The Decisional Matrix for Preceptorship Experiences (DMPE) was designed to support mutual needs assessment and identification of individualized clinical learning activities. Using the Andragogy in Practice…

  16. The Integrated Early Childhood Curriculum.

    Science.gov (United States)

    Krogh, Suzanne

    This textbook provides an outline of an integrated curriculum for early childhood education. Part 1 discusses the human element in school: the child and the teacher and child development. Part 2 contains the curriculum itself and covers the subjects of language, mathematics, science, social studies, art, music, and movement. Guidelines provide…

  17. The models of upbringing of children and youth as agents of cultural integration in the lives of Polish landowners during the Partitions of Poland [Wzorce wychowania dzieci i młodzieży jako element integrujący kulturę życia rodzinnego polskiego ziemiaństwa w dobie zaborów

    Directory of Open Access Journals (Sweden)

    Bołdyrew

    2011-01-01

    Full Text Available One of the most important tasks of a typical Polish gentry family by the end of the XIX-th century and at the beginning of the XX-th century was to hand down to younger generations patriotic values. To assure the continuity of the nation and to have the guarantee of the futurę freedom became sine qua non condition. It also became one of the main values of the gentry ethos. Gentry accepted the role of depositary of Polish nationality. The defeat of the November Uprising and the reprisals of the partitioning powers led to the radicalisation of attitudes, and of crucial importance became a principle to conflate the national cause with religion, which in tum led to crystallisation of the term „patriotic religion” whose upholder and priest became a woman - „Mother Pole”. Within the whole epoch the education of children was significant. In order to save them from the indoctrination they were taught national history, tradition and literature at home which stood in the opposition to the teaching officially practiced at school. The further evolution of the model was influenced greatly by the defeat of the January Uprising and the political and socio-economic transformations in the wake of it. The basis of a modem society was to be its young generation. It was their mother who were supposed to look after their health, bringing-up and education, and the postulates to improve the ąuality of parental care became one of the elements of „organie labour”. The new reality of life made it necessary by the end of the XIX-th century to reinterpret the idea of patriotic upbringing which was integrated with morał and hygienic education. In spite of numerous differences conceming the upbringing one can point to many common pattems of education of young generation. The models were not dependent on territorial, political or mental divisions which created so called “awareness of being one social body”. Family and social gatherings facilitated the

  18. The Chemistry of Superheavy Elements

    CERN Document Server

    Schädel, M

    2003-01-01

    The chemistry of transactinide or superheavy elements has reached element 108. Preparations are under way to leap to element 112 and beyond. The current status of this atom-at-a-time chemical research and its future perspectives are reviewed from an experimental point of view together with some of the interesting results from n -rich nuclides near and at the N=162 neutron shell. Experimental techniques and important results enlightening typical chemical properties of elements 104 through 108 are presented in an exemplary way. From the results of these experiments it is justified to place these elements in the Periodic Table of the Elements in to groups 4 through 8, respectively. However, mainly due to the influence of relativistic effects, it is no longer possible to deduce detailed chemical properties of these superheavy elements simply from this position.

  19. Transplutonium elements - a literature survey

    International Nuclear Information System (INIS)

    Sivaramakrishnan, C.K.; Jadhav, A.V.

    1974-01-01

    The report surveys reported work on the discovery of transplutonium elements and their production through various methods like bombardment of heavy elements with charged ions, successive neutron captures on heavy elements in reactors and multiple neutron captures by heavy elements during nuclear explosions. Estimated yields of transplutonium elements in special targets irradiated in reactors, and also as byproducts from spent power reactor fuels are quoted. Various chemical procedures adopted for recovery of these elements from irradiated target and also from power reactor fuel reprocessing streams are described. A brief survey of shielded facilities available at various centres for transplutonium programmes is also included. Major uses of some of these heavy elements are described. (author)

  20. Integrated Design

    DEFF Research Database (Denmark)

    Lenau, Torben Anker

    1999-01-01

    A homepage on the internet with course material, lecture plan, student exercises, etc. Continuesly updated during the course Integrated Design (80402, 80403)......A homepage on the internet with course material, lecture plan, student exercises, etc. Continuesly updated during the course Integrated Design (80402, 80403)...

  1. Finite element simulation and testing of ISW CFRP anchorage

    DEFF Research Database (Denmark)

    Schmidt, Jacob Wittrup; Goltermann, Per; Hertz, Kristian Dahl

    2013-01-01

    is modelled in the 3D finite Element program ABAQUS, just as digital image correlation (DIC) testing was performed to verify the finite element simulation. Also a new optimized design was produced to ensure that the finite element simulation and anchorage behaviour correlated well. It is seen....... This paper presents a novel mechanical integrated sleeve wedge anchorage which seem very promising when perusing the scope of ultimate utilization of CFRP 8mm rods (with a tension capacity of approximately 140kN). Compression transverse to the CFRP is evaluated to prevent premature failure. The anchorage...

  2. Organising integration

    DEFF Research Database (Denmark)

    Axelsson, Runo

    2013-01-01

    Background: In Sweden, as in many other countries, there has been a succession of trends in the organisation of health care and other welfare services. These trends have had different implications for the integration of services in the health and welfare system. Aims: One aim is to discuss...... the implications of different organisational trends for the integration of health and welfare services. Another aim is to introduce a Swedish model of financial coordination as a flexible way to organise integration. Organisational trends: In the 1960’s there was an expansion of health and welfare services leading...... an increasing lack of integration in the health and welfare system. In the 2000’s, there has been a re-centralisation through mergers of hospitals, regions and state agencies. It has become clear, however, that mergers do not promote integration but rather increase the bureaucratisation of the system. Model...

  3. The integration of immigrants

    OpenAIRE

    Bauböck, Rainer

    1995-01-01

    from the Table of Contents: Migration and integration - Basic concepts and definitions; Immigration and Integration policies; The legal framework for integration; Dimension of social integration; Cultural integration; Conclusions;

  4. Elements on reactor control

    International Nuclear Information System (INIS)

    Bruna, G.B.

    1998-01-01

    In order to achieve the two-fold goal of maximizing the energy obtained from reactor fuel and ensuring the large flexibility of plant operation in respect to safety regulations and keeping the reactor integrity the control of PWRs is generally based on real time monitoring and analysing of independent neutronic parameters: thermal power release, axial power distribution in the core and temperatures of the primary loop. Two control chains more or less coupled according to the control chosen mode are in charge of the control of these parameters. With the brief history of control in French power reactors the advanced X control mode adopted by Framatome for N4 plants is described in detail. A summary of N4 reactor control and protection system is included

  5. Fuel element services

    International Nuclear Information System (INIS)

    Marta, H.; Alvarez, P.; Jimenez, J.

    2006-01-01

    Refuelling outages comprise a number of maintenance tasks scheduled long in advance to assure a reliable operation throughout the next cycle and, in the long run, a safer and more efficient plant. Most of these tasks are routine service of mechanical and electrical system and likewise fuel an be considered a critical component as to handling, inspection, cleaning and repair. ENUSA-ENWESA AIE has been working in this area since 1995 growing from fuel repair to a more integrated service that includes new and spent fuel handling, inserts, failed fuel rod detection systems, ultrasonic fuel cleaning, fuel repair and a comprehensive array of inspection and tests related to the reliability of the mechanical components in the fuel assembly, all this, performed in compliance with quality, safety, health physics and any other nuclear standard. (Author)

  6. Integrative psychotherapy.

    Science.gov (United States)

    Kozarić-Kovacić, Dragica

    2008-09-01

    The main purposes of the article are to present the history of integration in psychotherapy, the reasons of the development integrative approaches, and the approaches to integration in psychotherapy. Three approaches to integration in psychotherapy exist: theoretical integration, theoretical eclecticism, and common factors in different psychotherapeutic trends. In integrative psychotherapy, the basic epistemology, theory, and clinical practice are based on the phenomenology, field theory, holism, dialogue, and co-creation of dialogue in the therapeutic relationship. The main criticism is that integrative psychotherapy suffers from confusion and many unresolved controversies. It is difficult to theoretically and methodologically define the clinically applied model that is based on such a different epistemological and theoretical presumptions. Integrative psychotherapy is a synthesis of humanistic psychotherapy, object relations theory, and psychoanalytical self psychology. It focuses on the dynamics and potentials of human relationships, with a goal of changing the relations and understanding internal and external resistances. The process of integrative psychotherapy is primarily focused on the developmental-relational model and co-creation of psychotherapeutic relationship as a single interactive event, which is not unilateral, but rather a joint endeavor by both the therapist and the patient/client. The need for a relationship is an important human need and represents a process of attunement that occurs as a response to the need for a relationship, a unique interpersonal contact between two people. If this need is not met, it manifests with the different feelings and various defenses. To meet this need, we need to have another person with whom we can establish a sensitive, attuned relationship. Thus, the therapist becomes this person who tries to supplement what the person did not receive. Neuroscience can be a source of integration through different therapies. We

  7. Integration of Chandrasekhar's integral equation

    International Nuclear Information System (INIS)

    Tanaka, Tasuku

    2003-01-01

    We solve Chandrasekhar's integration equation for radiative transfer in the plane-parallel atmosphere by iterative integration. The primary thrust in radiative transfer has been to solve the forward problem, i.e., to evaluate the radiance, given the optical thickness and the scattering phase function. In the area of satellite remote sensing, our problem is the inverse problem: to retrieve the surface reflectance and the optical thickness of the atmosphere from the radiance measured by satellites. In order to retrieve the optical thickness and the surface reflectance from the radiance at the top-of-the atmosphere (TOA), we should express the radiance at TOA 'explicitly' in the optical thickness and the surface reflectance. Chandrasekhar formalized radiative transfer in the plane-parallel atmosphere in a simultaneous integral equation, and he obtained the second approximation. Since then no higher approximation has been reported. In this paper, we obtain the third approximation of the scattering function. We integrate functions derived from the second approximation in the integral interval from 1 to ∞ of the inverse of the cos of zenith angles. We can obtain the indefinite integral rather easily in the form of a series expansion. However, the integrals at the upper limit, ∞, are not yet known to us. We can assess the converged values of those series expansions at ∞ through calculus. For integration, we choose coupling pairs to avoid unnecessary terms in the outcome of integral and discover that the simultaneous integral equation can be deduced to the mere integral equation. Through algebraic calculation, we obtain the third approximation as a polynomial of the third degree in the atmospheric optical thickness

  8. Integrated coherent matter wave circuits

    International Nuclear Information System (INIS)

    Ryu, C.; Boshier, M. G.

    2015-01-01

    An integrated coherent matter wave circuit is a single device, analogous to an integrated optical circuit, in which coherent de Broglie waves are created and then launched into waveguides where they can be switched, divided, recombined, and detected as they propagate. Applications of such circuits include guided atom interferometers, atomtronic circuits, and precisely controlled delivery of atoms. We report experiments demonstrating integrated circuits for guided coherent matter waves. The circuit elements are created with the painted potential technique, a form of time-averaged optical dipole potential in which a rapidly moving, tightly focused laser beam exerts forces on atoms through their electric polarizability. Moreover, the source of coherent matter waves is a Bose-Einstein condensate (BEC). Finally, we launch BECs into painted waveguides that guide them around bends and form switches, phase coherent beamsplitters, and closed circuits. These are the basic elements that are needed to engineer arbitrarily complex matter wave circuitry

  9. A refined element-based Lagrangian shell element for geometrically nonlinear analysis of shell structures

    Directory of Open Access Journals (Sweden)

    Woo-Young Jung

    2015-04-01

    Full Text Available For the solution of geometrically nonlinear analysis of plates and shells, the formulation of a nonlinear nine-node refined first-order shear deformable element-based Lagrangian shell element is presented. Natural co-ordinate-based higher order transverse shear strains are used in present shell element. Using the assumed natural strain method with proper interpolation functions, the present shell element generates neither membrane nor shear locking behavior even when full integration is used in the formulation. Furthermore, a refined first-order shear deformation theory for thin and thick shells, which results in parabolic through-thickness distribution of the transverse shear strains from the formulation based on the third-order shear deformation theory, is proposed. This formulation eliminates the need for shear correction factors in the first-order theory. To avoid difficulties resulting from large increments of the rotations, a scheme of attached reference system is used for the expression of rotations of shell normal. Numerical examples demonstrate that the present element behaves reasonably satisfactorily either for the linear or for geometrically nonlinear analysis of thin and thick plates and shells with large displacement but small strain. Especially, the nonlinear results of slit annular plates with various loads provided the benchmark to test the accuracy of related numerical solutions.

  10. EAF optimal managing elements

    Science.gov (United States)

    Ioana, A.; Constantin, N.; Dragna, E. C.

    2017-01-01

    Electric Arc Furnaces (EAF) is an important and complex aggregate. We present elements of EAF operating efficiency. The reliability of the EAF is mainly determined by electric circuit reliability and especially of the transformator of the furnace. This due to the fact that, in an electric steel plant, the objective „24 tapping/day” involves. Due to the complexity of the process, the EAF operation needs a computer usage and, in his componence, it must have two independent calculation units (UC1) and (UC2). Based on these two input sets (Σi1) and ((Σi2), the calculation unit (UC1) builds the general operation procedure based on mathematical methods. For that purpose, there are used the results of the 5 mathematical methods: the mathematical model to write-off the function objective (M.F.O.); the mathematical model of calculating the charge (M.C.C.); the mathematical model of conducting the effective melt (M.C.M.); the mathematical model of reheating the charge (M.R.C.); the mathematical model of blasting the reactive dusts (M.B.R.D.).

  11. Nuclear fuel element

    International Nuclear Information System (INIS)

    Armijo, J.S.

    1977-01-01

    A nuclear fuel element for use in the core of a nuclear reactor is disclosed which has a composite cladding having a substrate, a metal barrier metallurgically bonded to the inside surface of the substrate and an inner layer metallurgically bonded to the inside surface of the metal barrier. In this composite cladding, the inner layer and the metal barrier shield the substrate from any impurities or fission products from the nuclear fuel material held within the composite cladding. The metal barrier forms about 1 to about 4 percent of the thickness of the cladding and is comprised of a metal selected from the group consisting of niobium, aluminum, copper, nickel, stainless steel, and iron. The inner layer and then the metal barrier serve as reaction sites for volatile impurities and fission products and protect the substrate from contact and reaction with such impurities and fission products. The substrate and the inner layer of the composite cladding are selected from conventional cladding materials and preferably are a zirconium alloy. Also in a preferred embodiment the substrate and the inner layer are comprised of the same material, preferably a zirconium alloy. 19 claims, 2 figures

  12. Neutron absorbing element

    International Nuclear Information System (INIS)

    Kasai, Shigeo.

    1991-01-01

    The present invention concerns a neutron absorbing element of a neutron shielding member used for an LMFBR type reactor. The inside of a fuel can sealed at both of the upper and the lower ends thereof with plugs is partitioned into an upper and a lower chambers by an intermediate plug. A discharging hole is disposed at the upper end plug, which is in communication with the outside. A communication tube is disposed at the intermediate end plug and it is in communication with the lower chamber containing B 4 C pellets. A cylindrical support member having three porous plugs connected in series is disposed at the lower surface of the discharging hole provided at the upper end plug. Further, the end of the discharging hole is sealed with high temperature solder and He atmosphere is present at the inside of the fuel can. With such a constitution, the supporting differential pressure of the porous plugs can be made greater while discharging He gases generated from B 4 C to the outside. Further, the porous plugs can be surely wetted by coolants. Accordingly, it is possible to increase life time and shorten the size. (I.N.)

  13. Chemistry of transuranium elements

    International Nuclear Information System (INIS)

    Anon.

    1976-01-01

    The half-wave amalgamation potential of No (element 102) was determined. Studies on the preparation and properties of Cf are reported; previously reported results on Es were confirmed. The heat of solution of Bk was measured. Spectroscopic and x-ray diffraction studies of Es-253 bromides are reported. Salicylate complexes with Sm(III), Am(III), Th(IV), and U(IV)O 2 were prepared; crystal data are given. Results of studies on the effect of secondary bonds on the strength of O double bond Np double bond O bonds are reported. The M series x rays of Np were measured. Anomalous spin--orbit splitting of the 4f level in the actinide series is reported. Progress is reported in studies on the Cf oxide system for oxygen pressures up to 760 mm and temperatures between 25 and 1000 0 C, as well as structural parameters of transplutonium oxysulfates and oxysulfides and actinide and lanthanide hydroxides. The electron paramagnetic resonance spectrum of 253 Es 2+ was observed in the cubic monocrystal hosts BaF 2 and SrCl 2

  14. Chemistry of the superheavy elements.

    Science.gov (United States)

    Schädel, Matthias

    2015-03-13

    The quest for superheavy elements (SHEs) is driven by the desire to find and explore one of the extreme limits of existence of matter. These elements exist solely due to their nuclear shell stabilization. All 15 presently 'known' SHEs (11 are officially 'discovered' and named) up to element 118 are short-lived and are man-made atom-at-a-time in heavy ion induced nuclear reactions. They are identical to the transactinide elements located in the seventh period of the periodic table beginning with rutherfordium (element 104), dubnium (element 105) and seaborgium (element 106) in groups 4, 5 and 6, respectively. Their chemical properties are often surprising and unexpected from simple extrapolations. After hassium (element 108), chemistry has now reached copernicium (element 112) and flerovium (element 114). For the later ones, the focus is on questions of their metallic or possibly noble gas-like character originating from interplay of most pronounced relativistic effects and electron-shell effects. SHEs provide unique opportunities to get insights into the influence of strong relativistic effects on the atomic electrons and to probe 'relativistically' influenced chemical properties and the architecture of the periodic table at its farthest reach. In addition, they establish a test bench to challenge the validity and predictive power of modern fully relativistic quantum chemical models. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

  15. Experimental Study of Elements Promoting Mixing in Fuel Elements

    International Nuclear Information System (INIS)

    Silin, Nicolas; Juanico, Luis; Delmastro, Dario

    2003-01-01

    In the present work a thermal tracing technique is used to measure the increase of the mixing between subchannels in the presence of different mixing elements.As representative elements a spacer, a spacer with mixing vanes and turbulence promoter buttons were considered.The performance of these elements was evaluated by studying the behavior of a thermal trace in each case.Also the pressure drop for each case is presented.The results present a qualitative and quantitative guide for the application of each one of these appendages in future nuclear elements

  16. Integrating Technology: The Principals' Role and Effect

    Science.gov (United States)

    Machado, Lucas J.; Chung, Chia-Jung

    2015-01-01

    There are many factors that influence technology integration in the classroom such as teacher willingness, availability of hardware, and professional development of staff. Taking into account these elements, this paper describes research on technology integration with a focus on principals' attitudes. The role of the principal in classroom…

  17. Integrated marketing communications in sport organizations

    OpenAIRE

    Gašović Milan

    2011-01-01

    Integrated marketing communications represent the unification of organization's marketing and communication activities. Sports organizations have the emphasized need for effective communication with their environment (the public, the media, advertisers, sponsors, and other subjects interested in their offer). Elements of the integrated marketing communications are: advertising, personal selling, sales promotion, publicity, public relations, direct marketing, Internet communications etc. Each ...

  18. Integration of gastronomy and physics for innovation

    NARCIS (Netherlands)

    Linden, van der E.

    2013-01-01

    Integration of physics with gastronomy can yield innovations in an efficient manner. An important element of this integration is the structure of food. The creation of food recipes often deals with designing new structures and a clear understanding of how food structure influences food properties is

  19. Integrated services

    International Nuclear Information System (INIS)

    Chafcouloff, S.; Michel, G.; Trice, M.; Clark, G.; Cosad, C.; Forbes, K.

    1995-01-01

    Integrated services is the name given to several services grouped together under a single contract. Four key factors determine the success of integrated services projects: teamwork, common objectives, technology, and shared benefits. For oil companies, integration means smoother, more efficient operations by bringing service companies on board as part of the team. For the service industry, it means a radical change in the way business is conducted, taking on more responsibility in return for greater incentives. This article reviews the need for change and the approach Schlumberger has adopted to meet this challenge. 20 figs., 20 refs

  20. Integrated services

    Energy Technology Data Exchange (ETDEWEB)

    Chafcouloff, S.; Michel, G.; Trice, M. [Schlumberger Integrated Project Management Group, Montrouge (France); Clark, G. [Schlumberger Testing Services, Aberdeen (United Kingdom); Cosad, C.; Forbes, K. [Schlumberger Integrated Project Management Group, Aberdeen (United Kingdom)

    1995-12-31

    Integrated services is the name given to several services grouped together under a single contract. Four key factors determine the success of integrated services projects: teamwork, common objectives, technology, and shared benefits. For oil companies, integration means smoother, more efficient operations by bringing service companies on board as part of the team. For the service industry, it means a radical change in the way business is conducted, taking on more responsibility in return for greater incentives. This article reviews the need for change and the approach Schlumberger has adopted to meet this challenge. 20 figs., 20 refs

  1. Finite element simulation for creep crack growth

    International Nuclear Information System (INIS)

    Miyazaki, Noriyuki; Sasaki, Toru; Nakagaki, Michihiko; Brust, F.W.

    1992-01-01

    A finite element method was applied to a generation phase simulation of creep crack growth. Experimental data on creep crack growth in a 1Cr-1Mo-1/4V steel compact tension specimen were numerically simulated using a node-release technique and the variations of various fracture mechanics parameters such as CTOA, J, C * and T * during creep crack growth were calculated. The path-dependencies of the integral parameters J, C * and T * were also obtained to examine whether or not they could characterize the stress field near the tip of a crack propagating under creep condition. The following conclusions were obtained from the present analysis. (1) The J integral shows strong path-dependency during creep crack growth, so that it is does not characterize creep crack growth. (2) The C * integral shows path-dependency to some extent during creep crack growth even in the case of Norton type steady state creep law. Strictly speaking, we cannot use it as a fracture mechanics parameter characterizing creep crack growth. It is, however, useful from the practical viewpoint because it correlates well the rate of creep crack growth. (3) The T * integral shows good path-independency during creep crack growth. Therefore, it is a candidate for a fracture mechanics parameter characterizing creep crack growth. (author)

  2. Analog elements for transuranic chemistries

    International Nuclear Information System (INIS)

    Weimer, W.C.

    1982-01-01

    The analytical technique for measuring trace concentrations of the analog rare earth elements has been refined for optimal detection. The technique has been used to determine the rare earth concentrations in a series of geological and biological materials, including samples harvested from controlled lysimeter investigations. These studies have demonstrated that any of the trivalent rare earth elements may be used as analog elements for the trivalent transuranics, americium and curium

  3. INTEGRATED EDUCATION

    Directory of Open Access Journals (Sweden)

    Lioara-Bianca BUBOIU

    2015-04-01

    Full Text Available Accepting and valuing people with disabilities is a key aspect of social policies promoted worldwide. The implementation of these policies aim normalize the lives of people with disabilities through full integration in the society to which they belong. Removing discrimination and social barriers equates to a maturing of the society, maturing translated by accepting diversity that surrounds us. Each person must be appreciated at its true value regardless of its condition of normality or deviation from it. Valuing individuals can be achieved only through a full acceptance in society, by assigning statuses and fulfilling social roles. School integration of children with special educational needs in mainstream education is a challenge and involves many aspects to be successful. It is the premise of social integration, the basis for future socio-professional insertion. Integrated education is the first step towards a world of equal opportunities, a world without discrimination.

  4. Integral cryptanalysis

    DEFF Research Database (Denmark)

    Knudsen, Lars Ramkilde; Wagner, David

    2002-01-01

    This paper considers a cryptanalytic approach called integral cryptanalysis. It can be seen as a dual to differential cryptanalysis and applies to ciphers not vulnerable to differential attacks. The method is particularly applicable to block ciphers which use bijective components only.......This paper considers a cryptanalytic approach called integral cryptanalysis. It can be seen as a dual to differential cryptanalysis and applies to ciphers not vulnerable to differential attacks. The method is particularly applicable to block ciphers which use bijective components only....

  5. Five elements interferometrs

    Science.gov (United States)

    Sawant, H.

    The Brazilian Decimetric Array (BDA) is being developed at National Institute for Space Research (INPE) as an international collaborative program. Initially, the BDA will operate in a tuneable frequency range of 1.2 - 1.7 GHz and finally its range will be extended to 2.7 and 5.0 GHz. The initial planned baseline for BDA is 256 × 144 m and that will be extended to 2.2 × 1.1 km in the form of "T". In this paper, we present the results of developments concerning the prototype of BDA (PBDA). The PBDA will initially operate in the frequency range of 1.2 - 1.7 GHz only with a five-antenna array. The antennas employ 4-meter parabolic dishes with altitude and azimuth mountings with complete tracking capability. The spatial resolution for solar images with the PBDA will be about 3.5 arc-minutes leading to a sensitivity of ~2 × 104 mJy/beam for integration time of 1 sec. The array will be installed at -22o 41' 19" latitude and 45o 00' 22" W longitude and it is under operation between 9 and 21 UT for continuous solar flux monitoring. Details of the PBDA system and initial solar observations will be reported.

  6. Photoshop Elements 10 For Dummies

    CERN Document Server

    Obermeier, Barbara

    2011-01-01

    Perfect your photos and images with this "focused" guide to the latest version of Photoshop Elements For most of us, the professional-level Photoshop is overkill for our needs. Amateur photographers and photo enthusiasts turn to Photoshop Elements for a powerful but simpler way to edit and retouch their snapshots. Photoshop Elements 10 For Dummies, fully updated and revised for the latest release of this software product, helps you navigate Elements to create, edit, fix, share, and organize the high-quality images you desire. Full color pages bring the techniques to life and make taking great

  7. Systems integration.

    Science.gov (United States)

    Siemieniuch, C E; Sinclair, M A

    2006-01-01

    The paper presents a view of systems integration, from an ergonomics/human factors perspective, emphasising the process of systems integration as is carried out by humans. The first section discusses some of the fundamental issues in systems integration, such as the significance of systems boundaries, systems lifecycle and systems entropy, issues arising from complexity, the implications of systems immortality, and so on. The next section outlines various generic processes for executing systems integration, to act as guides for practitioners. These address both the design of the system to be integrated and the preparation of the wider system in which the integration will occur. Then the next section outlines some of the human-specific issues that would need to be addressed in such processes; for example, indeterminacy and incompleteness, the prediction of human reliability, workload issues, extended situation awareness, and knowledge lifecycle management. For all of these, suggestions and further readings are proposed. Finally, the conclusions section reiterates in condensed form the major issues arising from the above.

  8. Three dimensional finite element linear analysis of reinforced concrete structures

    International Nuclear Information System (INIS)

    Inbasakaran, M.; Pandarinathan, V.G.; Krishnamoorthy, C.S.

    1979-01-01

    A twenty noded isoparametric reinforced concrete solid element for the three dimensional linear elastic stress analysis of reinforced concrete structures is presented. The reinforcement is directly included as an integral part of the element thus facilitating discretization of the structure independent of the orientation of reinforcement. Concrete stiffness is evaluated by taking 3 x 3 x 3 Gauss integration rule and steel stiffness is evaluated numerically by considering three Gaussian points along the length of reinforcement. The numerical integration for steel stiffness necessiates the conversion of global coordiantes of the Gaussian points to nondimensional local coordinates and this is done by Newton Raphson iterative method. Subroutines for the above formulation have been developed and added to SAP and STAP routines for solving the examples. The validity of the reinforced concrete element is verified by comparison of results from finite element analysis and analytical results. It is concluded that this finite element model provides a valuable analytical tool for the three dimensional elastic stress analysis of concrete structures like beams curved in plan and nuclear containment vessels. (orig.)

  9. Imagery Integration Team

    Science.gov (United States)

    Calhoun, Tracy; Melendrez, Dave

    2014-01-01

    The Human Exploration Science Office (KX) provides leadership for NASA's Imagery Integration (Integration 2) Team, an affiliation of experts in the use of engineering-class imagery intended to monitor the performance of launch vehicles and crewed spacecraft in flight. Typical engineering imagery assessments include studying and characterizing the liftoff and ascent debris environments; launch vehicle and propulsion element performance; in-flight activities; and entry, landing, and recovery operations. Integration 2 support has been provided not only for U.S. Government spaceflight (e.g., Space Shuttle, Ares I-X) but also for commercial launch providers, such as Space Exploration Technologies Corporation (SpaceX) and Orbital Sciences Corporation, servicing the International Space Station. The NASA Integration 2 Team is composed of imagery integration specialists from JSC, the Marshall Space Flight Center (MSFC), and the Kennedy Space Center (KSC), who have access to a vast pool of experience and capabilities related to program integration, deployment and management of imagery assets, imagery data management, and photogrammetric analysis. The Integration 2 team is currently providing integration services to commercial demonstration flights, Exploration Flight Test-1 (EFT-1), and the Space Launch System (SLS)-based Exploration Missions (EM)-1 and EM-2. EM-2 will be the first attempt to fly a piloted mission with the Orion spacecraft. The Integration 2 Team provides the customer (both commercial and Government) with access to a wide array of imagery options - ground-based, airborne, seaborne, or vehicle-based - that are available through the Government and commercial vendors. The team guides the customer in assembling the appropriate complement of imagery acquisition assets at the customer's facilities, minimizing costs associated with market research and the risk of purchasing inadequate assets. The NASA Integration 2 capability simplifies the process of securing one

  10. Improved combination of photosensitivity elements for use in radiography

    International Nuclear Information System (INIS)

    Doorselaer, M.K.

    1975-01-01

    It is stated that manufacturers of photosensitive elements incorporating silver halide emulsions for use in radiography are often faced with performance requirements that place conflicting demands on the composition of the photosensitive elements. Amongst such performance requirements are a minimum photographic speed, a short processing time, and a minimum standard of image density and resolution. With a view to achieving some degree of reconciliation between maximum optical image density requirements and economy in processing time, and in particular fixing time, it is advantageous to have the total silver halide content distributed in emulsion layers on opposite sides of the emulsion layer support. Such 'double sided' elements are usually exposed between two intensifying screens, that may be separate elements of integral parts of a single element that also incorporates the silver halide emulsion layers. During exposure of these 'double sided' elements light from one intensifying screen irradiates the adjacent emulsion layer and also that on the opposite side of the support; this is referred to as 'cross over'. Due to refraction and other light deflection processes within the photosensitive element this, however, impairs image definition. In commercial systems a relatively high concentration of siver halide is usually employed in order to obtain good contrast and maximum image density, but this adversely affects processing time. Instead of such high silver halide concentrations emulsions of small silver halide grain size may be used, but this lowers the photographic speed. Elements having properties that mitigate these difficulties are described, and examples of their application are given. (U.K.)

  11. Laser assisted decontamination of nuclear fuel elements

    International Nuclear Information System (INIS)

    Padma Nilaya, J.; Biswas, Dhruba J.; Kumar, Aniruddha

    2010-04-01

    Laser assisted removal of loosely bound fuel particulates from the clad surface following the process of pellet loading has decided advantages over conventional methods. It is a dry and noncontact process that generates very little secondary waste and can occur inside a glove box without any manual interference minimizing the possibility of exposure to personnel. The rapid rise of the substrate/ particulate temperature owing to the absorption of energy from the incident laser pulse results in a variety of processes that may lead to the expulsion of the particulates. As a precursor to the cleaning of the fuel elements, initial experiments were carried out on contamination simulated on commonly used clad surfaces to gain a first hand experience on the various laser parameters for which as efficient cleaning can be obtained without altering the properties of the clad surface. The cleaning of a dummy fuel element was subsequently achieved in the laboratory by integrating the laser with a work station that imparted simultaneous rotational and linear motion to the fuel element. (author)

  12. Monitoring of trace element air pollution

    International Nuclear Information System (INIS)

    Freitas, M.C.; Gouveia, M.A.; Prudencio, M.I.; Ferreira, P.; Morgado, I.; Amaro, A.; Fernandes, T.; Dionisio, I.; Reis, M.A.; Alves, L.C.

    1994-01-01

    With this project, a biomonitoring survey will be carried out with epiphytic lichens. The lichens Parmelia sulcata (or caperata) will be collected from olive trees about 1-2 m above the ground, using a 10x10 km grid or 50x50 km gird. In total, about 300 sampling sites will be set up. Within one sampling site, variations in elemental concentrations of lichen material taken from several trees of the same species will be analyzed to obtained the local variation for each element (made in 10% of the grid). In addition some typical soil samples will be collected so that the contribution of soil suspended in air particulate matter can be recognized. The samples will be analyzed for ∼50 elements by NAA and PIXE. The expected results will be integrated data sets, which will be used in the next step for application of a statistical procedure to identify particular pollution sources. The project also consists of exposure experiments with lichen transplant samples at several sampling sites, which are representative for the regions under study. In addition at each sampling site air particular matter and total deposition will be collected monthly, during 1 year. The aim is to establish a quantitative relationship between results obtained with the lichen transplant samples and with air particulate matter and total deposition. (author). 12 refs, 2 figs, 2 tabs

  13. New mixed finite-element methods

    International Nuclear Information System (INIS)

    Franca, L.P.

    1987-01-01

    New finite-element methods are proposed for mixed variational formulations. The methods are constructed by adding to the classical Galerkin method various least-squares like terms. The additional terms involve integrals over element interiors, and include mesh-parameter dependent coefficients. The methods are designed to enhance stability. Consistency is achieved in the sense that exact solutions identically satisfy the variational equations.Applied to several problems, simple finite-element interpolations are rendered convergent, including convenient equal-order interpolations generally unstable within the Galerkin approach. The methods are subdivided into two classes according to the manner in which stability is attained: (1) circumventing Babuska-Brezzi condition methods; (2) satisfying Babuska-Brezzi condition methods. Convergence is established for each class of methods. Applications of the first class of methods to Stokes flow and compressible linear elasticity are presented. The second class of methods is applied to the Poisson, Timoshenko beam and incompressible elasticity problems. Numerical results demonstrate the good stability and accuracy of the methods, and confirm the error estimates

  14. Woody tissue analysis using an element ratio technique (DRIS)

    Science.gov (United States)

    Kurt H. Riitters; L.F. Ohmann; D.F. Grigal

    1991-01-01

    The diagnosis and recommendation integrated system (DRIS) was used to describe the variation of 12 elements in woody tree tissue and balsam fir (Abies balsamae (L.) Mill.), sugar maple (Acer saccharum Marsh.), jack pine (Pinus banksiana Lamb.), red pine (Pinus resinosa alt.), and aspen (

  15. Nonlinear nonstationary analysis with the finite element method

    International Nuclear Information System (INIS)

    Vaz, L.E.

    1981-01-01

    In this paper, after some introductory remarks on numerical methods for the integration of initial value problems, the applicability of the finite element method for transient diffusion analysis as well as dynamic and inelastic analysis is discussed, and some examples are presented. (RW) [de

  16. Using Game Elements to Increase Student Engagement in Course Assignments

    Science.gov (United States)

    Armier, David Des, Jr.; Shepherd, Craig E.; Skrabut, Stan

    2016-01-01

    Gamification incorporates game-elements in non-gaming situations to enhance student engagement and desired behavior. This study examined participant's willingness to take part in gamified activities where reward systems were not directly tied to course grades. Participants enrolled in a technology integration course for preservice teachers, were…

  17. Rare-earth elements

    Science.gov (United States)

    Van Gosen, Bradley S.; Verplanck, Philip L.; Seal, Robert R.; Long, Keith R.; Gambogi, Joseph; Schulz, Klaus J.; DeYoung,, John H.; Seal, Robert R.; Bradley, Dwight C.

    2017-12-19

    The rare-earth elements (REEs) are 15 elements that range in atomic number from 57 (lanthanum) to 71 (lutetium); they are commonly referred to as the “lanthanides.” Yttrium (atomic number 39) is also commonly regarded as an REE because it shares chemical and physical similarities and has affinities with the lanthanides. Although REEs are not rare in terms of average crustal abundance, the concentrated deposits of REEs are limited in number.Because of their unusual physical and chemical properties, the REEs have diverse defense, energy, industrial, and military technology applications. The glass industry is the leading consumer of REE raw materials, which are used for glass polishing and as additives that provide color and special optical properties to the glass. Lanthanum-based catalysts are used in petroleum refining, and cerium-based catalysts are used in automotive catalytic converters. The use of REEs in magnets is a rapidly increasing application. Neodymium-iron-boron magnets, which are the strongest known type of magnets, are used when space and weight are restrictions. Nickel-metal hydride batteries use anodes made of a lanthanum-based alloys.China, which has led the world production of REEs for decades, accounted for more than 90 percent of global production and supply, on average, during the past decade. Citing a need to retain its limited REE resources to meet domestic requirements as well as concerns about the environmental effects of mining, China began placing restrictions on the supply of REEs in 2010 through the imposition of quotas, licenses, and taxes. As a result, the global rare-earth industry has increased its stockpiling of REEs; explored for deposits outside of China; and promoted new efforts to conserve, recycle, and substitute for REEs. New mine production began at Mount Weld in Western Australia, and numerous other exploration and development projects noted in this chapter are ongoing throughout the world.The REE-bearing minerals are

  18. Pyrometallurgical processes for recovery of actinide elements

    International Nuclear Information System (INIS)

    Battles, J.E.; Laidler, J.J.; McPheeters, C.C.; Miller, W.E.

    1994-01-01

    A metallic fuel alloy, nominally U-20-Pu-lOZr, is the key element of the Integral Fast Reactor (IFR) fuel cycle. Metallic fuel permits the use of an innovative, simple pyrometallurgical process, known as pyroprocessing, (the subject of this report), which features fused salt electrorefining of the spent fuel. Electrorefining separates the actinide elements from fission products, without producing a separate stream of plutonium. The plutonium-bearing product is contaminated with higher actinides and with a minor amount of rare earth fission products, making it diversion resistant while still suitable as a fuel material in the fast spectrum of the IFR core. The engineering-scale demonstration of this process will be conducted in the refurbished EBR-II Fuel Cycle Facility, which has entered the start-up phase. An additional pyrometallurgical process is under development for extracting transuranic (TRU) elements from Light Water Reactor (LWR) spent fuel in a form suitable for use as a feed to the IFR fuel cycle. Four candidate extraction processes have been investigated and shown to be chemically feasible. The main steps in each process are oxide reduction with calcium or lithium, regeneration of the reductant and recycle of the salt, and separation of the TRU product from the bulk uranium. Two processes, referred to as the lithium and salt transport (calcium reductant) processes, have been selected for engineering-scale demonstration, which is expected to start in late 1993. An integral part of pyroprocessing development is the treatment and packaging of high-level waste materials arising from the operations, along with the qualification of these waste forms for disposal in a geologic repository

  19. Pyrometallurgical processes for recovery of actinide elements

    Energy Technology Data Exchange (ETDEWEB)

    Battles, J.E.; Laidler, J.J.; McPheeters, C.C.; Miller, W.E.

    1994-01-01

    A metallic fuel alloy, nominally U-20-Pu-lOZr, is the key element of the Integral Fast Reactor (IFR) fuel cycle. Metallic fuel permits the use of an innovative, simple pyrometallurgical process, known as pyroprocessing, (the subject of this report), which features fused salt electrorefining of the spent fuel. Electrorefining separates the actinide elements from fission products, without producing a separate stream of plutonium. The plutonium-bearing product is contaminated with higher actinides and with a minor amount of rare earth fission products, making it diversion resistant while still suitable as a fuel material in the fast spectrum of the IFR core. The engineering-scale demonstration of this process will be conducted in the refurbished EBR-II Fuel Cycle Facility, which has entered the start-up phase. An additional pyrometallurgical process is under development for extracting transuranic (TRU) elements from Light Water Reactor (LWR) spent fuel in a form suitable for use as a feed to the IFR fuel cycle. Four candidate extraction processes have been investigated and shown to be chemically feasible. The main steps in each process are oxide reduction with calcium or lithium, regeneration of the reductant and recycle of the salt, and separation of the TRU product from the bulk uranium. Two processes, referred to as the lithium and salt transport (calcium reductant) processes, have been selected for engineering-scale demonstration, which is expected to start in late 1993. An integral part of pyroprocessing development is the treatment and packaging of high-level waste materials arising from the operations, along with the qualification of these waste forms for disposal in a geologic repository.

  20. Thermally-induced bowing of CANDU fuel elements

    International Nuclear Information System (INIS)

    Suk, H.C.; Sim, K.S.; Park, J.H.; Park, G.S.

    1995-01-01

    Considering only the thermally-induced bending moments which are generated both within the sheath and between the fuel and sheath by an asymmetric temperature distribution with respect to the axis of an element, a generalized and explicit analytical formula for the thermally-induced bending is developed in this paper, based on the cases of 1) the bending of an empty tube treated by neglecting of the fuel/sheath mechanical interaction and 2) the fuel/sheath interaction due to the pellet and sheath temperature variations. In each of the cases, the temperature asymmetries in sheath are modelled to be caused by the combined effects of (i) non-uniform coolant temperature due to imperfect coolant mixing, (ii) variable sheath/coolant heat transfer coefficient, (iii) asymmetric heat generation due to neutron flux gradients across an element and so as to inclusively cover the uniform temperature distributions within the fuel and sheath with respect to the axial centerline. Investigating the relative importance of the various parameters affecting fuel element bowing, the element bowing is found to be greatly affected with the variations of element length, sheath diameter, pellet/sheath mechanical interaction and neutron flux depression factors, pellet thermal expansion coefficient, pellet/sheath heat transfer coefficient in comparison with those of other parameters such as sheath thickness, film heat transfer coefficient, sheath thermal expansion coefficient, and sheath and pellet thermal conductivities. Also, the element bowing of the standard 37-element bundle and CANFLEX 43-element bundle for the use in CANDU-6 reactors was analyzed with the formula, which could help to demonstrate the integrity of the fuel. All the required input data for the analyses were generated in terms of the reactor operation conditions on the reactor physics, thermal hydraulics and fuel performance by using various CANDU computer codes. The analysis results indicate that the CANFLEX 43-element