Multi-Objective Optimization in Physical Synthesis of Integrated Circuits

CERN Document Server

A Papa, David

2013-01-01

This book introduces techniques that advance the capabilities and strength of modern software tools for physical synthesis, with the ultimate goal to improve the quality of leading-edge semiconductor products.  It provides a comprehensive introduction to physical synthesis and takes the reader methodically from first principles through state-of-the-art optimizations used in cutting edge industrial tools. It explains how to integrate chip optimizations in novel ways to create powerful circuit transformations that help satisfy performance requirements. Broadens the scope of physical synthesis optimization to include accurate transformations operating between the global and local scales; Integrates groups of related transformations to break circular dependencies and increase the number of circuit elements that can be jointly optimized to escape local minima;  Derives several multi-objective optimizations from first observations through complete algorithms and experiments; Describes integrated optimization te...

Synthesis maps: visual knowledge translation for the CanIMPACT clinical system and patient cancer journeys.

Science.gov (United States)

Jones, P H; Shakdher, S; Singh, P

2017-04-01

Salient findings and interpretations from the canimpact clinical cancer research study are visually represented in two synthesis maps for the purpose of communicating an integrated presentation of the study to clinical cancer researchers and policymakers. Synthesis maps integrate evidence and expertise into a visual narrative for knowledge translation and communication. A clinical system synthesis map represents the current Canadian primary care and cancer practice systems, proposed as a visual knowledge translation from the mixed-methods canimpact study to inform Canadian clinical research, policy, and practice discourses. Two synthesis maps, drawn together from multiple canimpact investigations and sources, were required to articulate critical differences between the clinical system and patient perspectives. The synthesis map of Canada-wide clinical cancer systems illustrates the relationships between primary care and the full cancer continuum. A patient-centred map was developed to represent the cancer (and primary care) journeys as experienced by breast and colorectal cancer patients.

Indicators and measurement tools for health system integration : a knowledge synthesis protocol

OpenAIRE

Oelke, Nelly Donszelmann; Suter, Esther; Lima, Maria Alice Dias da Silva; Vliet-Brown, Cheryl Van

2015-01-01

Background: Health system integration is a key component of health system reform with the goal of improving outcomes for patients, providers, and the health system. Although health systems continue to strive for better integration, current delivery of health services continues to be fragmented. A key gap in the literature is the lack of information on what successful integration looks like and how to measure achievement towards an integrated system. This multi-site study protocol builds on a ...

AutoBayes Program Synthesis System System Internals

Science.gov (United States)

Schumann, Johann Martin

2011-01-01

This lecture combines the theoretical background of schema based program synthesis with the hands-on study of a powerful, open-source program synthesis system (Auto-Bayes). Schema-based program synthesis is a popular approach toward program synthesis. The lecture will provide an introduction into this topic and discuss how this technology can be used to generate customized algorithms. The synthesis of advanced numerical algorithms requires the availability of a powerful symbolic (algebra) system. Its task is to symbolically solve equations, simplify expressions, or to symbolically calculate derivatives (among others) such that the synthesized algorithms become as efficient as possible. We will discuss the use and importance of the symbolic system for synthesis. Any synthesis system is a large and complex piece of code. In this lecture, we will study Autobayes in detail. AutoBayes has been developed at NASA Ames and has been made open source. It takes a compact statistical specification and generates a customized data analysis algorithm (in C/C++) from it. AutoBayes is written in SWI Prolog and many concepts from rewriting, logic, functional, and symbolic programming. We will discuss the system architecture, the schema libary and the extensive support infra-structure. Practical hands-on experiments and exercises will enable the student to get insight into a realistic program synthesis system and provides knowledge to use, modify, and extend Autobayes.

Catalyst synthesis and evaluation using an integrated atomic layer deposition synthesis–catalysis testing tool

International Nuclear Information System (INIS)

Camacho-Bunquin, Jeffrey; Shou, Heng; Marshall, Christopher L.; Aich, Payoli; Beaulieu, David R.; Klotzsch, Helmut; Bachman, Stephen; Hock, Adam; Stair, Peter

2015-01-01

An integrated atomic layer deposition synthesis-catalysis (I-ALD-CAT) tool was developed. It combines an ALD manifold in-line with a plug-flow reactor system for the synthesis of supported catalytic materials by ALD and immediate evaluation of catalyst reactivity using gas-phase probe reactions. The I-ALD-CAT delivery system consists of 12 different metal ALD precursor channels, 4 oxidizing or reducing agents, and 4 catalytic reaction feeds to either of the two plug-flow reactors. The system can employ reactor pressures and temperatures in the range of 10 −3 to 1 bar and 300–1000 K, respectively. The instrument is also equipped with a gas chromatograph and a mass spectrometer unit for the detection and quantification of volatile species from ALD and catalytic reactions. In this report, we demonstrate the use of the I-ALD-CAT tool for the synthesis of platinum active sites and Al 2 O 3 overcoats, and evaluation of catalyst propylene hydrogenation activity

Catalyst synthesis and evaluation using an integrated atomic layer deposition synthesis–catalysis testing tool

Energy Technology Data Exchange (ETDEWEB)

Camacho-Bunquin, Jeffrey; Shou, Heng; Marshall, Christopher L. [Chemical Sciences and Engineering Division, Argonne National Laboratory, Lemont, Illinois 60439 (United States); Aich, Payoli [Chemical Sciences and Engineering Division, Argonne National Laboratory, Lemont, Illinois 60439 (United States); Department of Chemical Engineering, University of Illinois at Chicago, Chicago, Illinois 60607 (United States); Beaulieu, David R.; Klotzsch, Helmut; Bachman, Stephen [Arradiance Inc., Sudbury, Massachusetts 01776 (United States); Hock, Adam [Chemical Sciences and Engineering Division, Argonne National Laboratory, Lemont, Illinois 60439 (United States); Department of Chemistry, Illinois Institute of Technology, Chicago, Illinois 60616 (United States); Stair, Peter [Chemical Sciences and Engineering Division, Argonne National Laboratory, Lemont, Illinois 60439 (United States); Department of Chemistry, Northwestern University, Evanston, Illinois 60208 (United States)

2015-08-15

An integrated atomic layer deposition synthesis-catalysis (I-ALD-CAT) tool was developed. It combines an ALD manifold in-line with a plug-flow reactor system for the synthesis of supported catalytic materials by ALD and immediate evaluation of catalyst reactivity using gas-phase probe reactions. The I-ALD-CAT delivery system consists of 12 different metal ALD precursor channels, 4 oxidizing or reducing agents, and 4 catalytic reaction feeds to either of the two plug-flow reactors. The system can employ reactor pressures and temperatures in the range of 10{sup −3} to 1 bar and 300–1000 K, respectively. The instrument is also equipped with a gas chromatograph and a mass spectrometer unit for the detection and quantification of volatile species from ALD and catalytic reactions. In this report, we demonstrate the use of the I-ALD-CAT tool for the synthesis of platinum active sites and Al{sub 2}O{sub 3} overcoats, and evaluation of catalyst propylene hydrogenation activity.

On the Automated Synthesis of Enterprise Integration Patterns to Adapt Choreography-based Distributed Systems

Directory of Open Access Journals (Sweden)

Marco Autili

2015-12-01

Full Text Available The Future Internet is becoming a reality, providing a large-scale computing environments where a virtually infinite number of available services can be composed so to fit users' needs. Modern service-oriented applications will be more and more often built by reusing and assembling distributed services. A key enabler for this vision is then the ability to automatically compose and dynamically coordinate software services. Service choreographies are an emergent Service Engineering (SE approach to compose together and coordinate services in a distributed way. When mismatching third-party services are to be composed, obtaining the distributed coordination and adaptation logic required to suitably realize a choreography is a non-trivial and error prone task. Automatic support is then needed. In this direction, this paper leverages previous work on the automatic synthesis of choreography-based systems, and describes our preliminary steps towards exploiting Enterprise Integration Patterns to deal with a form of choreography adaptation.

Design and evaluation of an integrated safeguards system: principles

International Nuclear Information System (INIS)

Markin, J.T.; Coulter, C.A.; Gutmacher, R.G.; Whitty, W.J.

1984-01-01

An integrated safeguards system is defined as a collection of safeguards activities in which system components are coordinated to meet safeguards objectives efficiently within constraints imposed by safeguards resources, facility operations, potential adversaries, and regulatory requirements. This paper describes principles for designing and evaluating an integrated safeguards system that consists of four parts: a problem definition phase that specifies resources and constraints composing the problem boundary values, a system analysis/synthesis phase that describes how to select and integrate safeguards activities for efficient attainment of system objectives, a system evaluation/optimization phase that defines measures of safeguards performance and develops methods for evaluating them, and a decision-making phase that develops principles for selecting admissible designs and preference-ordering designs

Synthesis for the Interdisciplinary Environmental Sciences: Integrating Systems Approaches and Service Learning

Science.gov (United States)

Simon, Gregory L.; Wee, Bryan Shao-Chang; Chin, Anne; Tindle, Amy Depierre; Guth, Dan; Mason, Hillary

2013-01-01

As our understanding of complex environmental issues increases, institutions of higher education are evolving to develop new learning models that emphasize synthesis across disciplines, concepts, data, and methodologies. To this end, we argue for the implementation of environmental science education at the intersection of systems theory and…

Integrated system for design and analysis of industrial processes with electrolyte system

DEFF Research Database (Denmark)

Takano, Kiyoteru; Gani, Rafiqul

1999-01-01

of thermodynamic insights not only to generate process alternatives but also to obtain good initial estimates for the simulation engine and for visualization of process synthesis/design. The main steps of the algorithm are highlighted through a case study involving an industrial crystallization process.......An algorithm for design and analysis of crystallization processes with electrolyte systems is presented. This algorithm consists of a thermodynamic part, a synthesis part and a design part. The three parts are integrated through a simulation engine. The main features of the algorithm is the use...

Design and evaluation of an integrated safeguards system: principles

International Nuclear Information System (INIS)

Markin, J.T.; Coulter, C.A.; Gutmacher, R.G.; Whitty, W.J.

1984-07-01

An integrated safeguards system is defined as a collection of safeguards activities in which system components are coordinated to meet safeguards objectives efficiently within constraints imposed by safeguards resources, facility operations, potential adversaries, and regulatory requirements. This paper describes principles for designing and evaluating an integrated safeguards system that consists of four parts: (1) a problem definition phase that specifies resources and constraints composing the problem boundary values; (2) a system analysis/synthesis phase that describes how to select and integrate safeguards activities for efficient attainment of system objectives; (3) a system evaluation/optimization phase that defines measures of safeguards performance and develops methods for evaluating them; and (4) a decision-making phase that develops principles for selecting admissible designs and preference-ordering designs. 6 references, 4 figures, 5 tables

Promoting better integration of health information systems: best practices and challenges

NARCIS (Netherlands)

Michelsen, K.; Brand, H.; Achterberg, P.; Wilkinson, J.

2015-01-01

Health Evidence Network Synthesis Report [Promoting better integration of health information systems: best practices and challenges K Michelsen, H Brand, P Achterberg, J Wilkinson - 2015 ... Authors Kai Michelsen Department of International Health, Maastricht University Maastricht,

Integration of thermodynamic insights and MINLP optimisation for the synthesis, design and analysis of process flowsheets

DEFF Research Database (Denmark)

Hostrup, Martin; Gani, Rafiqul; Kravanja, Zdravko

1999-01-01

This paper presents an integrated approach to the solution of process synthesis, design and analysis problems. Integration is achieved by combining two different techniques, synthesis based on thermodynamic insights and structural optimization together with a simulation engine and a properties pr...

Power Systems Integration Laboratory | Energy Systems Integration Facility

Science.gov (United States)

| NREL Power Systems Integration Laboratory Power Systems Integration Laboratory Research in the Energy System Integration Facility's Power Systems Integration Laboratory focuses on the microgrid applications. Photo of engineers testing an inverter in the Power Systems Integration Laboratory

Experimental Investigation and Modeling of Integrated Tri-generation Systems

Science.gov (United States)

Cetinkaya, Eda

Energy demand in the world is increasing with population growth and higher living standards. Today, the need for energy requires a focus on renewable sources without abandoning fossil fuels. Efficient use of energy is one of the most important tasks in modern energy systems to achieve. In addition to the energy need, growing environmental concerns are linked with energy is emerged. Multi-purpose energy generation allows a higher efficiency by generating more outputs with the same input in the same system. Tri-generation systems are expected to provide at least three commodities, such as heating, cooling, desalination, storable fuel production and some other useful outputs, in addition to power generation. In this study, an experimental investigation of gasification is presented and two integrated tri-generation systems are proposed. The first integrated tri-generation system (System 1) utilizes solar energy as input and the outputs are power, fresh water and hot water. It consists of four sub-systems, namely solar power tower system, desalination system, Rankine cycle and organic Rankine cycle (ORC). The second integrated tri-generation system (System 2) utilizes coal and biomass as input and the outputs are power, fuel and hot water. It consists of five sub-systems: gasification plant, Brayton cycle, Rankine cycle, Fischer-Tropsch synthesis plant and an organic Rankine cycle (ORC). Experimental investigation includes coal and biomass gasification, where the experimental results of synthesis gas compositions are utilized in the analysis of the second systems. To maximize efficiency, heat losses from the system should be minimized through a recovery system to make the heat a useful commodity for other systems, such as ORCs which can utilize the low-grade heat. In this respect, ORCs are first analyzed for three different configurations in terms of energy and exergy efficiencies altering working fluids to increase the power output. Among two types of coal and one type

Integrating Emotions Into the Critical Interpretive Synthesis.

Science.gov (United States)

McFerran, Katrina Skewes; Hense, Cherry; Medcalf, Laura; Murphy, Melissa; Fairchild, Rebecca

2017-01-01

Critical interpretive synthesis is a particular form of systematic review that critically examines the decisions made by authors while conducting and publishing about their research and practices. It differs from empirical syntheses of qualitative research by emphasizing the interpreted and constructed nature of this form of secondary analysis. In this article, we extend previous literature on critical interpretive syntheses by highlighting the integration of emotional responses when developing critical questions for interrogating the literature and interpreting results. Our extension of the critical interpretive synthesis is illustrated through examples from five studies examining literature in our own field of music therapy, as well as related fields of disability studies, mental health, music psychology, and child welfare. The methodology we have refined uses an iterative and recursive method that promotes increased critical awareness of the assumptions driving the production of research in health contexts. © The Author(s) 2016.

Integration of supervisory control synthesis in model-based systems engineering

NARCIS (Netherlands)

Baeten, J.C.M.; van de Mortel - Fronczak, J.M.; Rooda, J.E.

2016-01-01

Increasing system complexity, time to market and development costs reduction place higher demands on engineering processes. Formal models play an important role here because they enable the use of various model-based analyses and early integration techniques and tools. Engineering processes based on

Integration of Predictive Display and Aircraft Flight Control System

Directory of Open Access Journals (Sweden)

Efremov A.V.

2017-01-01

Full Text Available The synthesis of predictive display information and direct lift control system are considered for the path control tracking tasks (in particular landing task. The both solutions are based on pilot-vehicle system analysis and requirements to provide the highest accuracy and lowest pilot workload. The investigation was carried out for cases with and without time delay in aircraft dynamics. The efficiency of the both ways for the flying qualities improvement and their integration is tested by ground based simulation.

What Is Energy Systems Integration? | Energy Systems Integration Facility |

Science.gov (United States)

NREL What Is Energy Systems Integration? What Is Energy Systems Integration? Energy systems integration (ESI) is an approach to solving big energy challenges that explores ways for energy systems to Research Community NREL is a founding member of the International Institute for Energy Systems Integration

Energy Systems Integration Laboratory | Energy Systems Integration Facility

Science.gov (United States)

| NREL Integration Laboratory Energy Systems Integration Laboratory Research in the Energy Systems Integration Laboratory is advancing engineering knowledge and market deployment of hydrogen technologies. Applications include microgrids, energy storage for renewables integration, and home- and station

Energy Systems Integration Facility Videos | Energy Systems Integration

Science.gov (United States)

Facility | NREL Energy Systems Integration Facility Videos Energy Systems Integration Facility Integration Facility NREL + SolarCity: Maximizing Solar Power on Electrical Grids Redefining What's Possible for Renewable Energy: Grid Integration Robot-Powered Reliability Testing at NREL's ESIF Microgrid

Perceptually informed synthesis of bandlimited classical waveforms using integrated polynomial interpolation.

Science.gov (United States)

Välimäki, Vesa; Pekonen, Jussi; Nam, Juhan

2012-01-01

Digital subtractive synthesis is a popular music synthesis method, which requires oscillators that are aliasing-free in a perceptual sense. It is a research challenge to find computationally efficient waveform generation algorithms that produce similar-sounding signals to analog music synthesizers but which are free from audible aliasing. A technique for approximately bandlimited waveform generation is considered that is based on a polynomial correction function, which is defined as the difference of a non-bandlimited step function and a polynomial approximation of the ideal bandlimited step function. It is shown that the ideal bandlimited step function is equivalent to the sine integral, and that integrated polynomial interpolation methods can successfully approximate it. Integrated Lagrange interpolation and B-spline basis functions are considered for polynomial approximation. The polynomial correction function can be added onto samples around each discontinuity in a non-bandlimited waveform to suppress aliasing. Comparison against previously known methods shows that the proposed technique yields the best tradeoff between computational cost and sound quality. The superior method amongst those considered in this study is the integrated third-order B-spline correction function, which offers perceptually aliasing-free sawtooth emulation up to the fundamental frequency of 7.8 kHz at the sample rate of 44.1 kHz. © 2012 Acoustical Society of America.

The evolution of the protein synthesis system. I - A model of a primitive protein synthesis system

Science.gov (United States)

Mizutani, H.; Ponnamperuma, C.

1977-01-01

A model is developed to describe the evolution of the protein synthesis system. The model is comprised of two independent autocatalytic systems, one including one gene (A-gene) and two activated amino acid polymerases (O and A-polymerases), and the other including the addition of another gene (N-gene) and a nucleotide polymerase. Simulation results have suggested that even a small enzymic activity and polymerase specificity could lead the system to the most accurate protein synthesis, as far as permitted by transitions to systems with higher accuracy.

Systems integration.

Science.gov (United States)

Siemieniuch, C E; Sinclair, M A

2006-01-01

The paper presents a view of systems integration, from an ergonomics/human factors perspective, emphasising the process of systems integration as is carried out by humans. The first section discusses some of the fundamental issues in systems integration, such as the significance of systems boundaries, systems lifecycle and systems entropy, issues arising from complexity, the implications of systems immortality, and so on. The next section outlines various generic processes for executing systems integration, to act as guides for practitioners. These address both the design of the system to be integrated and the preparation of the wider system in which the integration will occur. Then the next section outlines some of the human-specific issues that would need to be addressed in such processes; for example, indeterminacy and incompleteness, the prediction of human reliability, workload issues, extended situation awareness, and knowledge lifecycle management. For all of these, suggestions and further readings are proposed. Finally, the conclusions section reiterates in condensed form the major issues arising from the above.

Subtask 2.4 - Integration and Synthesis in Climate Change Predictive Modeling

Energy Technology Data Exchange (ETDEWEB)

Jaroslav Solc

2009-06-01

The Energy & Environmental Research Center (EERC) completed a brief evaluation of the existing status of predictive modeling to assess options for integration of our previous paleohydrologic reconstructions and their synthesis with current global climate scenarios. Results of our research indicate that short-term data series available from modern instrumental records are not sufficient to reconstruct past hydrologic events or predict future ones. On the contrary, reconstruction of paleoclimate phenomena provided credible information on past climate cycles and confirmed their integration in the context of regional climate history is possible. Similarly to ice cores and other paleo proxies, acquired data represent an objective, credible tool for model calibration and validation of currently observed trends. It remains a subject of future research whether further refinement of our results and synthesis with regional and global climate observations could contribute to improvement and credibility of climate predictions on a regional and global scale.

Energy Systems Integration News | Energy Systems Integration Facility |

Science.gov (United States)

the Energy Systems Integration Facility as part of NREL's work with SolarCity and the Hawaiian Electric Companies. Photo by Amy Glickson, NREL Welcome to Energy Systems Integration News, NREL's monthly date on the latest energy systems integration (ESI) developments at NREL and worldwide. Have an item

Listening to another sense: somatosensory integration in the auditory system.

Science.gov (United States)

Wu, Calvin; Stefanescu, Roxana A; Martel, David T; Shore, Susan E

2015-07-01

Conventionally, sensory systems are viewed as separate entities, each with its own physiological process serving a different purpose. However, many functions require integrative inputs from multiple sensory systems and sensory intersection and convergence occur throughout the central nervous system. The neural processes for hearing perception undergo significant modulation by the two other major sensory systems, vision and somatosensation. This synthesis occurs at every level of the ascending auditory pathway: the cochlear nucleus, inferior colliculus, medial geniculate body and the auditory cortex. In this review, we explore the process of multisensory integration from (1) anatomical (inputs and connections), (2) physiological (cellular responses), (3) functional and (4) pathological aspects. We focus on the convergence between auditory and somatosensory inputs in each ascending auditory station. This review highlights the intricacy of sensory processing and offers a multisensory perspective regarding the understanding of sensory disorders.

Glucose Synthesis in a Protein-Based Artificial Photosynthesis System.

Science.gov (United States)

Lu, Hao; Yuan, Wenqiao; Zhou, Jack; Chong, Parkson Lee-Gau

2015-09-01

The objective of this study was to understand glucose synthesis of a protein-based artificial photosynthesis system affected by operating conditions, including the concentrations of reactants, reaction temperature, and illumination. Results from non-vesicle-based glyceraldehyde-3-phosphate (GAP) and glucose synthesis showed that the initial concentrations of ribulose-1,5-bisphosphate (RuBP) and adenosine triphosphate (ATP), lighting source, and temperature significantly affected glucose synthesis. Higher initial concentrations of RuBP and ATP significantly enhanced GAP synthesis, which was linearly correlated to glucose synthesis, confirming the proper functions of all catalyzing enzymes in the system. White fluorescent light inhibited artificial photosynthesis and reduced glucose synthesis by 79.2 % compared to in the dark. The reaction temperature of 40 °C was optimum, whereas lower or higher temperature reduced glucose synthesis. Glucose synthesis in the vesicle-based artificial photosynthesis system reconstituted with bacteriorhodopsin, F 0 F 1 ATP synthase, and polydimethylsiloxane-methyloxazoline-polydimethylsiloxane triblock copolymer was successfully demonstrated. This system efficiently utilized light-induced ATP to drive glucose synthesis, and 5.2 μg ml(-1) glucose was synthesized in 0.78-ml reaction buffer in 7 h. Light-dependent reactions were found to be the bottleneck of the studied artificial photosynthesis system.

Energy and resource basis of an Italian coastal resort region integrated using emergy synthesis.

Science.gov (United States)

Vassallo, Paolo; Paoli, Chiara; Tilley, David R; Fabiano, Mauro

2009-10-01

Sustainable development of coastal zones must balance economic development that encourages human visitation from a larger population with desires that differ from the local residents with the need to maintain opportunities for the local resident society and conserve ecological capital, which may serve as the basis for residents. We present a case study in which the sustainability level of a coastal zone (Riviera del Beigua), located along the Ligurian coast of north-western Italy, was assessed through the lens of systems ecology using emergy synthesis to integrate across economic, social and environmental sub-systems. Our purposes were (1) to quantify the environmental sustainability level of this coastal zone, (2) to evaluate the role of tourism in affecting the economy, society and environment, and (3) to compare emergy synthesis to Butler's Tourism Area Life Cycle model (TALC). Results showed that 81% of the total emergy consumption in the coastal zone was derived from external sources, indicating that this tourist-heavy community was not sustainable. Tourism, as the dominant economic sub-system, consumed 42% of the total emergy budget, while local residents used the remaining 58%. The progressive stages of the TALC model were found to parallel the dynamic changes in the ratio of external emergy inputs to local emergy inputs, suggesting that emergy synthesis could be a useful tool for detecting a tourist region's TALC stage. Use of such a quantitative tool could expedite sustainability assessment to allow administrative managers to understand the complex relationship between a region's economy, environment and resident society so sound policies can be developed to improve overall sustainability.

BILINGUAL MULTIMODAL SYSTEM FOR TEXT-TO-AUDIOVISUAL SPEECH AND SIGN LANGUAGE SYNTHESIS

Directory of Open Access Journals (Sweden)

A. A. Karpov

2014-09-01

Full Text Available We present a conceptual model, architecture and software of a multimodal system for audio-visual speech and sign language synthesis by the input text. The main components of the developed multimodal synthesis system (signing avatar are: automatic text processor for input text analysis; simulation 3D model of human's head; computer text-to-speech synthesizer; a system for audio-visual speech synthesis; simulation 3D model of human’s hands and upper body; multimodal user interface integrating all the components for generation of audio, visual and signed speech. The proposed system performs automatic translation of input textual information into speech (audio information and gestures (video information, information fusion and its output in the form of multimedia information. A user can input any grammatically correct text in Russian or Czech languages to the system; it is analyzed by the text processor to detect sentences, words and characters. Then this textual information is converted into symbols of the sign language notation. We apply international «Hamburg Notation System» - HamNoSys, which describes the main differential features of each manual sign: hand shape, hand orientation, place and type of movement. On their basis the 3D signing avatar displays the elements of the sign language. The virtual 3D model of human’s head and upper body has been created using VRML virtual reality modeling language, and it is controlled by the software based on OpenGL graphical library. The developed multimodal synthesis system is a universal one since it is oriented for both regular users and disabled people (in particular, for the hard-of-hearing and visually impaired, and it serves for multimedia output (by audio and visual modalities of input textual information.

Embedded System Synthesis under Memory Constraints

DEFF Research Database (Denmark)

Madsen, Jan; Bjørn-Jørgensen, Peter

1999-01-01

This paper presents a genetic algorithm to solve the system synthesis problem of mapping a time constrained single-rate system specification onto a given heterogeneous architecture which may contain irregular interconnection structures. The synthesis is performed under memory constraints, that is......, the algorithm takes into account the memory size of processors and the size of interface buffers of communication links, and in particular the complicated interplay of these. The presented algorithm is implemented as part of the LY-COS cosynthesis system....

Synthesis and Assimilation Systems - Essential Adjuncts to the Global Ocean Observing System

Science.gov (United States)

Rienecker, Michele M.; Balmaseda, Magdalena; Awaji, Toshiyuki; Barnier, Bernard; Behringer, David; Bell, Mike; Bourassa, Mark; Brasseur, Pierre; Breivik, Lars-Anders; Carton, James;

System-Level Modeling and Synthesis Techniques for Flow-Based Microfluidic Very Large Scale Integration Biochips

DEFF Research Database (Denmark)

Minhass, Wajid Hassan

Microfluidic biochips integrate different biochemical analysis functionalities on-chip and offer several advantages over the conventional biochemical laboratories. In this thesis, we focus on the flow-based biochips. The basic building block of such a chip is a valve which can be fabricated at very...... propose a framework for mapping the biochemical applications onto the mVLSI biochips, binding and scheduling the operations and performing fluid routing. A control synthesis framework for determining the exact valve activation sequence required to execute the application is also proposed. In order...... to reduce the macro-assembly around the chip and enhance chip scalability, we propose an approach for the biochip pin count minimization. We also propose a throughput maximization scheme for the cell culture mVLSI biochips, saving time and reducing costs. We have extensively evaluated the proposed...

Design, Specification, and Synthesis of Aircraft Electric Power Systems Control Logic

Science.gov (United States)

Xu, Huan

Cyber-physical systems integrate computation, networking, and physical processes. Substantial research challenges exist in the design and verification of such large-scale, distributed sensing, actuation, and control systems. Rapidly improving technology and recent advances in control theory, networked systems, and computer science give us the opportunity to drastically improve our approach to integrated flow of information and cooperative behavior. Current systems rely on text-based specifications and manual design. Using new technology advances, we can create easier, more efficient, and cheaper ways of developing these control systems. This thesis will focus on design considerations for system topologies, ways to formally and automatically specify requirements, and methods to synthesize reactive control protocols, all within the context of an aircraft electric power system as a representative application area. This thesis consists of three complementary parts: synthesis, specification, and design. The first section focuses on the synthesis of central and distributed reactive controllers for an aircraft elec- tric power system. This approach incorporates methodologies from computer science and control. The resulting controllers are correct by construction with respect to system requirements, which are formulated using the specification language of linear temporal logic (LTL). The second section addresses how to formally specify requirements and introduces a domain-specific language for electric power systems. A software tool automatically converts high-level requirements into LTL and synthesizes a controller. The final sections focus on design space exploration. A design methodology is proposed that uses mixed-integer linear programming to obtain candidate topologies, which are then used to synthesize controllers. The discrete-time control logic is then verified in real-time by two methods: hardware and simulation. Finally, the problem of partial observability and

Energy Systems Integration News - October 2016 | Energy Systems Integration

Science.gov (United States)

Facility | NREL October 2016 Energy Systems Integration News A monthly recap of the latest energy systems integration (ESI) developments at NREL and around the world. Subscribe Archives October Integration Facility's main control room. OMNETRIC Group Demonstrates a Distributed Control Hierarchy for

Integrating cell-free biosyntheses of heme prosthetic group and apoenzyme for the synthesis of functional P450 monooxygenase.

Science.gov (United States)

Kwon, Yong-Chan; Oh, In-Seok; Lee, Nahum; Lee, Kyung-Ho; Yoon, Yeo Joon; Lee, Eun Yeol; Kim, Byung-Gee; Kim, Dong-Myung

2013-04-01

Harnessing the isolated protein synthesis machinery, cell-free protein synthesis reproduces the cellular process of decoding genetic information in artificially controlled environments. More often than not, however, generation of functional proteins requires more than simple translation of genetic sequences. For instance, many of the industrially important enzymes require non-protein prosthetic groups for biological activity. Herein, we report the complete cell-free biogenesis of a heme prosthetic group and its integration with concurrent apoenzyme synthesis for the production of functional P450 monooxygenase. Step reactions required for the syntheses of apoenzyme and the prosthetic group have been designed so that these two separate pathways take place in the same reaction mixture, being insulated from each other. Combined pathways for the synthesis of functional P450 monooxygenase were then further integrated with in situ assay reactions to enable real-time measurement of enzymatic activity during its synthesis. Copyright © 2012 Wiley Periodicals, Inc.

Robust Hinfinity position control synthesis of an electro-hydraulic servo system.

Science.gov (United States)

Milić, Vladimir; Situm, Zeljko; Essert, Mario

2010-10-01

This paper focuses on the use of the techniques based on linear matrix inequalities for robust H(infinity) position control synthesis of an electro-hydraulic servo system. A nonlinear dynamic model of the hydraulic cylindrical actuator with a proportional valve has been developed. For the purpose of the feedback control an uncertain linearized mathematical model of the system has been derived. The structured (parametric) perturbations in the electro-hydraulic coefficients are taken into account. H(infinity) controller extended with an integral action is proposed. To estimate internal states of the electro-hydraulic servo system an observer is designed. Developed control algorithms have been tested experimentally in the laboratory model of an electro-hydraulic servo system. Copyright © 2010 ISA. Published by Elsevier Ltd. All rights reserved.

Energy Systems Integration Facility News | Energy Systems Integration

Science.gov (United States)

Facility | NREL Energy Systems Integration Facility News Energy Systems Integration Facility Energy Dataset A massive amount of wind data was recently made accessible online, greatly expanding the Energy's National Renewable Energy Laboratory (NREL) has completed technology validation testing for Go

B827 Chemical Synthhesis Project - Industrial Control System Integration - Statement of Work & Specification with Attachments 1-14

Energy Technology Data Exchange (ETDEWEB)

Wade, F. E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2017-04-21

The Chemical Synthesis Pilot Process at the Lawrence Livermore National Laboratory (LLNL) Site 300 827 Complex will be used to synthesize small quantities of material to support research and development. The project will modernize and increase current capabilities for chemical synthesis at LLNL. The primary objective of this project is the conversion of a non-automated hands-on process to a remoteoperation process, while providing enhanced batch process step control, stored recipe-specific parameter sets, process variable visibility, monitoring, alarm and warning handling, and comprehensive batch record data logging. This Statement of Work and Specification provides the industrial-grade process control requirements for the chemical synthesis batching control system, hereafter referred to as the “Control System” to be delivered by the System Integrator.

Development of an integration mutagenesis system in Lactobacillus gasseri.

Science.gov (United States)

Selle, Kurt; Goh, Yong Jun; O'Flaherty, Sarah; Klaenhammer, Todd R

2014-01-01

Lactobacillus gasseri ATCC 33323 is a member of the acidophilus-complex group, microbes of human origin with significant potential for impacting human health based on niche-specific traits. In order to facilitate functional analysis of this important species, a upp-based counterselective chromosomal integration system was established and employed for targeting the lipoteichoic acid (LTA) synthesis gene, ltaS, in L. gasseri ATCC 33323. The ltaS gene encodes a phosphoglycerol transferase responsible for building the glycerol chain of LTA. No isogenic mutant bearing the deletion genotype was recovered, but an integration knockout mutant was generated with insertion inactivation at the ltaS locus. The ltaS deficient derivative exhibited an altered cellular morphology and significantly reduced ability to adhere to Caco-2 intestinal cell monolayers, relative to the wild-type parent strain.

Tools for chemical synthesis in microsystems

OpenAIRE

Jensen, Klavs F.; Newman, Stephen G.; Reizman, Brandon Jacob

2014-01-01

Chemical synthesis in microsystems has evolved from simple proof-of-principle examples to become a general technique in academia and industry. Numerous such “flow chemistry” applications are now found in pharmaceutical and fine chemical synthesis. Much of the development has been based on systems employing macroscopic flow components and tubes, rather than the integrated chip technology envisioned by the lab-on-a-chip community. We review the major developments in systems for flow chemistry a...

Synthesis of milligram quantities of proteins using a reconstituted in vitro protein synthesis system.

Science.gov (United States)

Kazuta, Yasuaki; Matsuura, Tomoaki; Ichihashi, Norikazu; Yomo, Tetsuya

2014-11-01

In this study, the amount of protein synthesized using an in vitro protein synthesis system composed of only highly purified components (the PURE system) was optimized. By varying the concentrations of each system component, we determined the component concentrations that result in the synthesis of 0.38 mg/mL green fluorescent protein (GFP) in batch mode and 3.8 mg/mL GFP in dialysis mode. In dialysis mode, protein concentrations of 4.3 and 4.4 mg/mL were synthesized for dihydrofolate reductase and β-galactosidase, respectively. Using the optimized system, the synthesized protein represented 30% (w/w) of the total protein, which is comparable to the level of overexpressed protein in Escherichia coli cells. This optimized reconstituted in vitro protein synthesis system may potentially be useful for various applications, including in vitro directed evolution of proteins, artificial cell assembly, and protein structural studies. Copyright © 2014 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

Engineered Barrier System - Mechanical Integrity of KBS-3 Spent Fuel Canisters. Report from a Workshop. Synthesis and extended abstracts

Energy Technology Data Exchange (ETDEWEB)

2007-09-15

SKI is preparing to review the license applications being developed by the Swedish Nuclear Fuel and Waste Management Company (SKB) for a final repository for the geological disposal of spent nuclear fuel in the year 2009. As part of its preparation, SKI is conducting a series of technical workshops on key aspects of the Engineered Barrier System (EBS). The workshop reported here mainly dealt with the mechanical integrity of KBS-3 spent fuel canisters. This included assessment and review of various loading conditions, structural integrity models and mechanical properties of the copper shell and the cast iron insert. Degradation mechanisms such as stress corrosion cracking and brittle creep fracture were also briefly addressed. Previous workshops have addressed the overall concept for long-term integrity of the EBS, the manufacturing, testing and QA of the EBS, the performance confirmation for the EBS, long-term stability of the buffer and the backfill, corrosion properties of copper canisters and the spent fuel dissolution and source term modelling. The goal of ongoing review work in connection of the workshop series is to achieve a comprehensive overview of all aspects of SKB's EBS and spent fuel work prior to the handling of the forthcoming license application. This report aims to summarise the issues discussed at the workshop and to extract the essential viewpoints that have been expressed. The report is not a comprehensive record of all the discussions at the workshop, and individual statements made by workshop participants should be regarded as personal opinions rather than SKI viewpoints. Results from the EBS workshops series will be used as one important basis in future review work. This reports includes in addition to the workshop synthesis, questions to SKB identified prior to the workshop, and extended abstracts for introductory presentations

ANALYTICAL SYNTHESIS OF CHEMICAL REACTOR CONTROL SYSTEM

Directory of Open Access Journals (Sweden)

Alexander Labutin

2017-02-01

Full Text Available The problem of the analytical synthesis of the synergetic control system of chemical reactor for the realization of a complex series-parallel exothermal reaction has been solved. The synthesis of control principles is performed using the analytical design method of aggregated regulators. Synthesized nonlinear control system solves the problem of stabilization of the concentration of target component at the exit of reactor and also enables one to automatically transfer to new production using the equipment.

Techno-economic assessment of integrating methanol or Fischer-Tropsch synthesis in a South African sugar mill.

Science.gov (United States)

Petersen, Abdul M; Farzad, Somayeh; Görgens, Johann F

2015-05-01

This study considered an average-sized sugar mill in South Africa that crushes 300 wet tonnes per hour of cane, as a host for integrating methanol and Fischer-Tropsch synthesis, through gasification of a combined flow of sugarcane trash and bagasse. Initially, it was shown that the conversion of biomass to syngas is preferably done by catalytic allothermal gasification instead of catalytic autothermal gasification. Thereafter, conventional and advanced synthesis routes for both Methanol and Fischer-Tropsch products were simulated with Aspen Plus® software and compared by technical and economic feasibility. Advanced FT synthesis satisfied the overall energy demands, but was not economically viable for a private investment. Advanced methanol synthesis is also not viable for private investment since the internal rate of return was 21.1%, because it could not provide the steam that the sugar mill required. The conventional synthesis routes had less viability than the corresponding advanced synthesis routes. Copyright © 2015 Elsevier Ltd. All rights reserved.

Methods of Synthesis of Automatic Control Systems with Delay

Directory of Open Access Journals (Sweden)

Aliaksandr Lapeta

2013-05-01

Full Text Available The paper investigates the procedure for introduction of systems containing delay elements. Shortcomings and difficulties in the synthesis of regulators and precompensators of control systems with delays in output and control channel where determined. The author focused on two approaches for the formation of promatrix and synthesis of control systems, considering the factor of delay.

Retrofitting the AutoBayes Program Synthesis System with Concrete Syntax

Science.gov (United States)

Fischer, Bernd; Visser, Eelco

2004-01-01

AutoBayes is a fully automatic, schema-based program synthesis system for statistical data analysis applications. Its core component is a schema library. i.e., a collection of generic code templates with associated applicability constraints which are instantiated in a problem-specific way during synthesis. Currently, AutoBayes is implemented in Prolog; the schemas thus use abstract syntax (i.e., Prolog terms) to formulate the templates. However, the conceptual distance between this abstract representation and the concrete syntax of the generated programs makes the schemas hard to create and maintain. In this paper we describe how AutoBayes is retrofitted with concrete syntax. We show how it is integrated into Prolog and describe how the seamless interaction of concrete syntax fragments with AutoBayes's remaining legacy meta-programming kernel based on abstract syntax is achieved. We apply the approach to gradually mitigate individual schemas without forcing a disruptive migration of the entire system to a different First experiences show that a smooth migration can be achieved. Moreover, it can result in a considerable reduction of the code size and improved readability of the code. In particular, abstracting out fresh-variable generation and second-order term construction allows the formulation of larger continuous fragments.

Integral consideration of integrated management systems

International Nuclear Information System (INIS)

Frauenknecht, Stefan; Schmitz, Hans

2010-01-01

Aim of the project for the NPPs Kruemmel and Brunsbuettel (Vattenfall) is the integral view of the business process as basis for the implementation and operation of management systems in the domains quality, safety and environment. The authors describe the integral view of the business processes in the frame of integrated management systems with the focus nuclear safety, lessons learned in the past, the concept of a process-based controlling system and experiences from the practical realization.

Stellar population synthesis

International Nuclear Information System (INIS)

Pickles, A.J.

1989-01-01

The techniques used to derive astrophysically useful information from observations of the integrated light of composite stellar systems are briefly reviewed. A synthesis technique, designed to separate and describe on a standard system the competing effects of age and metallicity variations is introduced, and illustrated by its application to the study of the history of star formation in bright elliptical galaxies in clusters. (author)

Integrated Business and Engineering Framework for Synthesis and Design of Enterprise-Wide Processing Networks

DEFF Research Database (Denmark)

Quaglia, Alberto; Sarup, Bent; Sin, Gürkan

2012-01-01

The synthesis and design of processing networks is a complex and multidisciplinary problem, which involves many strategic and tactical decisions at business (considering financial criteria, market competition, supply chain network, etc) and engineering levels (considering synthesis, design...... and optimisation of production technology, R&D, etc), all of which have a deep impact on the profitability of processing industries. In this study, an integrated business and engineering framework for synthesis and design of processing networks is presented. The framework employs a systematic approach to manage...... the complexity while solving simultaneously both the business and the engineering aspects of problems, allowing at the same time, comparison of a large number of alternatives at their optimal points. The results identify the optimal raw material, the product portfolio and select the process technology...

Lutetium-177 DOTATATE Production with an Automated Radiopharmaceutical Synthesis System.

Science.gov (United States)

Aslani, Alireza; Snowdon, Graeme M; Bailey, Dale L; Schembri, Geoffrey P; Bailey, Elizabeth A; Pavlakis, Nick; Roach, Paul J

2015-01-01

Peptide Receptor Radionuclide Therapy (PRRT) with yttrium-90 ((90)Y) and lutetium-177 ((177)Lu)-labelled SST analogues are now therapy option for patients who have failed to respond to conventional medical therapy. In-house production with automated PRRT synthesis systems have clear advantages over manual methods resulting in increasing use in hospital-based radiopharmacies. We report on our one year experience with an automated radiopharmaceutical synthesis system. All syntheses were carried out using the Eckert & Ziegler Eurotope's Modular-Lab Pharm Tracer® automated synthesis system. All materials and methods used were followed as instructed by the manufacturer of the system (Eckert & Ziegler Eurotope, Berlin, Germany). Sterile, GMP-certified, no-carrier added (NCA) (177)Lu was used with GMP-certified peptide. An audit trail was also produced and saved by the system. The quality of the final product was assessed after each synthesis by ITLC-SG and HPLC methods. A total of 17 [(177)Lu]-DOTATATE syntheses were performed between August 2013 and December 2014. The amount of radioactive [(177)Lu]-DOTATATE produced by each synthesis varied between 10-40 GBq and was dependant on the number of patients being treated on a given day. Thirteen individuals received a total of 37 individual treatment administrations in this period. There were no issues and failures with the system or the synthesis cassettes. The average radiochemical purity as determined by ITLC was above 99% (99.8 ± 0.05%) and the average radiochemical purity as determined by HPLC technique was above 97% (97.3 ± 1.5%) for this period. The automated synthesis of [(177)Lu]-DOTATATE using Eckert & Ziegler Eurotope's Modular-Lab Pharm Tracer® system is a robust, convenient and high yield approach to the radiolabelling of DOTATATE peptide benefiting from the use of NCA (177)Lu and almost negligible radiation exposure of the operators.

Feasibility study on blast furnace ironmaking system integrated with methanol synthesis for reduction of carbon dioxide emission with effective use of energy

Energy Technology Data Exchange (ETDEWEB)

Akiyama, T [and others; Tohoku University, Sendai (Japan)

1993-01-01

The system proposed involves injection of natural gas at the tuyeres to reduce coke consumption, and methanol synthesis from the top gas. Operating data are calculated with a mathematical model, showing that significant reductions in emission of greenhouse gases and in exergy losses can be expected. (Development of an effective catalyst for the methanol synthesis is described in a companion paper: A. Muramatsu et al., 1144-1149).

Hierarchical modeling and robust synthesis for the preliminary design of large scale complex systems

Science.gov (United States)

Koch, Patrick Nathan

Large-scale complex systems are characterized by multiple interacting subsystems and the analysis of multiple disciplines. The design and development of such systems inevitably requires the resolution of multiple conflicting objectives. The size of complex systems, however, prohibits the development of comprehensive system models, and thus these systems must be partitioned into their constituent parts. Because simultaneous solution of individual subsystem models is often not manageable iteration is inevitable and often excessive. In this dissertation these issues are addressed through the development of a method for hierarchical robust preliminary design exploration to facilitate concurrent system and subsystem design exploration, for the concurrent generation of robust system and subsystem specifications for the preliminary design of multi-level, multi-objective, large-scale complex systems. This method is developed through the integration and expansion of current design techniques: (1) Hierarchical partitioning and modeling techniques for partitioning large-scale complex systems into more tractable parts, and allowing integration of subproblems for system synthesis, (2) Statistical experimentation and approximation techniques for increasing both the efficiency and the comprehensiveness of preliminary design exploration, and (3) Noise modeling techniques for implementing robust preliminary design when approximate models are employed. The method developed and associated approaches are illustrated through their application to the preliminary design of a commercial turbofan turbine propulsion system; the turbofan system-level problem is partitioned into engine cycle and configuration design and a compressor module is integrated for more detailed subsystem-level design exploration, improving system evaluation.

Searching for integrable systems

International Nuclear Information System (INIS)

Cary, J.R.

1984-01-01

Lack of integrability leads to undesirable consequences in a number of physical systems. The lack of integrability of the magnetic field leads to enhanced particle transport in stellarators and tokamaks with tearing-mode turbulence. Limitations of the luminosity of colliding beams may be due to the onset of stochasticity. Enhanced radial transport in mirror machines caused by the lack of integrability and/or the presence of resonances may be a significant problem in future devices. To improve such systems one needs a systematic method for finding integrable systems. Of course, it is easy to find integrable systems if no restrictions are imposed; textbooks are full of such examples. The problem is to find integrable systems given a set of constraints. An example of this type of problem is that of finding integrable vacuum magnetic fields with rotational transform. The solution to this problem is relevant to the magnetic-confinement program

Integration Host Factor (IHF binds to the promoter region of the phtD operon involved in phaseolotoxin synthesis in P. syringae pv. phaseolicola NPS3121

Directory of Open Access Journals (Sweden)

Álvarez-Morales Ariel

2011-05-01

Full Text Available Abstract Background Pseudomonas syringae pv. phaseolicola, the causal agent of halo blight disease in beans, produces a toxin known as phaseolotoxin, in whose synthesis participate a group of genes organized within the genome in a region known as the "Pht cluster". This region, which is thought to have been acquired by horizontal gene transfer, includes 5 transcriptional units, two monocistronic (argK, phtL and three polycistronic (phtA, phtD, phtM, whose expression is temperature dependent. So far, the regulatory mechanisms involved in phaseolotoxin synthesis have not been elucidated and the only well-established fact is the requirement of low temperatures for its synthesis. In this work, we searched for regulatory proteins that could be involved in phaseolotoxin synthesis, focusing on the regulation of the phtD operon. Results In this study we identified the global regulator IHF (Integration Host Factor, which binds to the promoter region of the phtD operon, exerting a negative effect on the expression of this operon. This is the first regulatory protein identified as part of the phaseolotoxin synthesis system. Our findings suggest that the Pht cluster was similarly regulated in the ancestral cluster by IHF or similar protein, and integrated into the global regulatory mechanism of P. syringae pv. phaseolicola, after the horizontal gene transfer event by using the host IHF protein. Conclusion This study identifies the IHF protein as one element involved in the regulation of phaseolotoxin synthesis in P. syringae pv. phaseolicola NPS3121 and provides new insights into the regulatory mechanisms involved in phaseolotoxin production.

Robust control synthesis for uncertain dynamical systems

Science.gov (United States)

Byun, Kuk-Whan; Wie, Bong; Sunkel, John

1989-01-01

This paper presents robust control synthesis techniques for uncertain dynamical systems subject to structured parameter perturbation. Both QFT (quantitative feedback theory) and H-infinity control synthesis techniques are investigated. Although most H-infinity-related control techniques are not concerned with the structured parameter perturbation, a new way of incorporating the parameter uncertainty in the robust H-infinity control design is presented. A generic model of uncertain dynamical systems is used to illustrate the design methodologies investigated in this paper. It is shown that, for a certain noncolocated structural control problem, use of both techniques results in nonminimum phase compensation.

Synthesis of dexterity measure of mechanisms by evolution of dissipative system

Directory of Open Access Journals (Sweden)

Grešl M.

2007-11-01

Full Text Available The paper deals with the new approach of solving traditional kinematical synthesis of mechanisms. The kinematical synthesis is reformulated as nonlinear dynamical problem. All searched parameters of the mechanism are in this dynamical dissipative system introduced as time-varying during motion of mechanism’s dimension iteration. The synthesis process is realized as the time evolution of such system. One of the most important objectives of the machine synthesis is the dexterity measure. The new approach is applied to optimization of this property.

Analysis and Synthesis of Distributed Real-Time Embedded Systems

DEFF Research Database (Denmark)

Pop, Paul; Eles, Petru; Peng, Zebo

like automotive electronics, real-time multimedia, avionics, medical equipment, and factory systems. The proposed analysis and synthesis techniques derive optimized implementations that fulfill the imposed design constraints. An important part of the implementation process is the synthesis...

VHDL for logic synthesis

CERN Document Server

Rushton, Andrew

2011-01-01

Many engineers encountering VHDL (very high speed integrated circuits hardware description language) for the first time can feel overwhelmed by it. This book bridges the gap between the VHDL language and the hardware that results from logic synthesis with clear organisation, progressing from the basics of combinational logic, types, and operators; through special structures such as tristate buses, register banks and memories, to advanced themes such as developing your own packages, writing test benches and using the full range of synthesis types. This third edition has been substantially rewritten to include the new VHDL-2008 features that enable synthesis of fixed-point and floating-point hardware. Extensively updated throughout to reflect modern logic synthesis usage, it also contains a complete case study to demonstrate the updated features. Features to this edition include: * a common VHDL subset which will work across a range of different synthesis systems, targeting a very wide range of technologies...

The Synthesis of Intelligent Real-Time Systems

Science.gov (United States)

1990-11-09

Synthesis of Intelligent Real - Time Systems . The purpose of the effort was to develop and extend theories and techniques that facilitate the design and...implementation of intelligent real - time systems . In particular, Teleos has extended situated-automata theory to apply to situations in which the system has

Integrated microfluidic devices for the synthesis of nanoscale liposomes and lipoplexes.

Science.gov (United States)

Balbino, Tiago A; Serafin, Juliana M; Radaic, Allan; de Jesus, Marcelo B; de la Torre, Lucimara G

2017-04-01

In this work, pDNA/cationic liposome (CL) lipoplexes for gene delivery were prepared in one-step using multiple hydrodynamic flow-focusing regions. The microfluidic platform was designed with two distinct regions for the synthesis of liposomes and the subsequent assembly with pDNA, forming lipoplexes. The obtained lipoplexes exhibited appropriate physicochemical characteristics for gene therapy applications under varying conditions of flow rate-ratio (FRR), total volumetric flow rate (Q T ) and pDNA content (molar charge ratio, R±). The CLs were able to condense and retain the pDNA in the vesicular structures with sizes ranging from 140nm to 250nm. In vitro transfection assays showed that the lipoplexes prepared in one step by the two-stage configuration achieved similar efficiencies as lipoplexes prepared by conventional bulk processes, in which each step comprises a series of manual operations. The integrated microfluidic platform generates lipoplexes with liposome formation combined in-line with lipoplex assembly, significantly reducing the number of steps usually required to form gene carrier systems. Copyright © 2017 Elsevier B.V. All rights reserved.

TCR industrial system integration strategy

CERN Document Server

Bartolomé, R; Sollander, P; Martini, R; Vercoutter, B; Trebulle, M

1999-01-01

New turnkey data acquisition systems purchased from industry are being integrated into CERN's Technical Data Server. The short time available for system integration and the large amount of data per system require a standard and modular design. Four different integration layers have been defined in order to easily 'plug in' industrial systems. The first layer allows the integration of the equipment at the digital I/O port or fieldbus (Profibus-DP) level. A second layer permits the integration of PLCs (Siemens S5, S7 and Telemecanique); a third layer integrates equipment drivers. The fourth layer integrates turnkey mimic diagrams in the TCR operator console. The second and third layers use two new event-driven protocols based on TCP/IP. Using this structure, new systems are integrated in the data transmission chain, the layer at which they are integrated depending only on their integration capabilities.

Systems Integration | Photovoltaic Research | NREL

Science.gov (United States)

Integration Systems Integration The National Center for Photovoltaics (NCPV) at NREL provides grid integration support, system-level testing, and systems analysis for the Department of Energy's solar distributed grid integration projects supported by the SunShot Initiative. These projects address technical

Choosing the Right Systems Integration

Directory of Open Access Journals (Sweden)

Péči Matúš

2014-12-01

Full Text Available The paper examines systems integration and its main levels at higher levels of control. At present, the systems integration is one of the main aspects participating in the consolidation processes and financial flows of a company. Systems Integration is a complicated emotionconsuming process and it is often a problem to choose the right approach and level of integration. The research focused on four levels of integration, while each of them is characterized by specific conditions. At each level, there is a summary of recommendations and practical experience. The paper also discusses systems integration between the information and MES levels. The main part includes user-level integration where we describe an example of such integration. Finally, we list recommendations and also possible predictions of the systems integration as one of the important factors in the future.

Automated Controller Synthesis for non-Deterministic Piecewise-Affine Hybrid Systems

DEFF Research Database (Denmark)

Grunnet, Jacob Deleuran

formations. This thesis uses a hybrid systems model of a satellite formation with possible actuator faults as a motivating example for developing an automated control synthesis method for non-deterministic piecewise-affine hybrid systems (PAHS). The method does not only open an avenue for further research...... in fault tolerant satellite formation control, but can be used to synthesise controllers for a wide range of systems where external events can alter the system dynamics. The synthesis method relies on abstracting the hybrid system into a discrete game, finding a winning strategy for the game meeting...... game and linear optimisation solvers for controller refinement. To illustrate the efficacy of the method a reoccurring satellite formation example including actuator faults has been used. The end result is the application of PAHSCTRL on the example showing synthesis and simulation of a fault tolerant...

Avionics systems integration technology

Science.gov (United States)

Stech, George; Williams, James R.

1988-01-01

A very dramatic and continuing explosion in digital electronics technology has been taking place in the last decade. The prudent and timely application of this technology will provide Army aviation the capability to prevail against a numerically superior enemy threat. The Army and NASA have exploited this technology explosion in the development and application of avionics systems integration technology for new and future aviation systems. A few selected Army avionics integration technology base efforts are discussed. Also discussed is the Avionics Integration Research Laboratory (AIRLAB) that NASA has established at Langley for research into the integration and validation of avionics systems, and evaluation of advanced technology in a total systems context.

System integration for radiation records

International Nuclear Information System (INIS)

Lawson, B.J.; Farrell, L.; Meacham, C.; Tapio, J.

1994-01-01

System integration is the process where through networking and/or software development, necessary business information is available in a common computing environment. System integration is becoming an important objective for many businesses. System integration can improve productivity and efficiency, reduce redundant stored information and errors, and improve availability of information. This paper will discuss the information flow in a radiation health environment, and how system integration can help. Information handled includes external dosimetry and internal dosimetry. The paper will focus on an ORACLE based system integration software product

Integrated management systems

CERN Document Server

Bugdol, Marek

2015-01-01

Examining the challenges of integrated management, this book explores the importance and potential benefits of using an integrated approach as a cross-functional concept of management. It covers not only standardized management systems (e.g. International Organization for Standardization), but also models of self-assessment, as well as different types of integration. Furthermore, it demonstrates how processes and systems can be integrated, and how management efficiency can be increased. The major part of this book focuses on management concepts which use integration as a key tool of management processes (e.g. the systematic approach, supply chain management, virtual and network organizations, processes management and total quality management). Case studies, illustrations, and tables are also provided to exemplify and illuminate the content, as well as examples of successful and failed integrations. Providing a particularly useful resource to managers and specialists involved in the improvement of organization...

Automated Synthesis of 68Ga-DOTA-TOC: Methodological Aspects and Suitable Technical Solutions for a Cationic Purification System.

Science.gov (United States)

Uccelli, Licia; Boschi, Alessandra; Cittanti, Corrado; Martini, Petra; Lodi, Luca; Zappaterra, Elisa; Romani, Simona; Zaccaria, Samanta; Cecconi, Davide; Rambaldi, Ilaria; Santi, Ivan; Panareo, Stefano; Giganti, Melchiore; Bartolomei, Mirco

2018-05-08

The PET Gallium-68 isotope has the advantage of being produced from a generator, so it is also available in nuclear medicine departments without a cyclotron. The preparation of Ga-68 DOTA-labelled compounds is actually performed by remotely controlled automated systems developed in order to assure production efficiency, reproducibility of the results, guarantee fast reaction time, to facilitate the synthesis and minimize the radiation exposure. Many automatic synthesis systems are available on the radiopharmaceutical market, and each of these requires the realization of some technical adaptations for routine use. We reported the Ga-68 DOTATOC production by automated cassette-based theranostic synthesizer system used in combination with a disposable GMP grade cassette system for cationic purification. The synthesizer is integrated with the 68Ge/68Ga generator systems and it allows to perform elution, eluate purification and radiolabeling in about 38 minutes. We have performed between January 2016 and January 2017 over 100 [68Ga]Ga-DOTA-TOC preparation and of these only three have failed. The average synthesis yield of radiopharmaceutical production was 54.4 ± 2.3 % and the average radiochemical purity was 96.94 ± 0.74 %. The methodology and the technical solutions adopted have allowed to obtain a high quality radiopharmaceutical product as required by the European Pharmacopoeia. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Virtual Reality System with Integrated Sound Field Simulation and Reproduction

Directory of Open Access Journals (Sweden)

Ingo Assenmacher

2007-01-01

Full Text Available A real-time audio rendering system is introduced which combines a full room-specific simulation, dynamic crosstalk cancellation, and multitrack binaural synthesis for virtual acoustical imaging. The system is applicable for any room shape (normal, long, flat, coupled, independent of the a priori assumption of a diffuse sound field. This provides the possibility of simulating indoor or outdoor spatially distributed, freely movable sources and a moving listener in virtual environments. In addition to that, near-to-head sources can be simulated by using measured near-field HRTFs. The reproduction component consists of a headphone-free reproduction by dynamic crosstalk cancellation. The focus of the project is mainly on the integration and interaction of all involved subsystems. It is demonstrated that the system is capable of real-time room simulation and reproduction and, thus, can be used as a reliable platform for further research on VR applications.

An automated synthesis-purification-sample-management platform for the accelerated generation of pharmaceutical candidates.

Science.gov (United States)

Sutherland, J David; Tu, Noah P; Nemcek, Thomas A; Searle, Philip A; Hochlowski, Jill E; Djuric, Stevan W; Pan, Jeffrey Y

2014-04-01

A flexible and integrated flow-chemistry-synthesis-purification compound-generation and sample-management platform has been developed to accelerate the production of small-molecule organic-compound drug candidates in pharmaceutical research. Central to the integrated system is a Mitsubishi robot, which hands off samples throughout the process to the next station, including synthesis and purification, sample dispensing for purity and quantification analysis, dry-down, and aliquot generation.

Calculation of partial molar volume of components in supercritical ammonia synthesis system

Institute of Scientific and Technical Information of China (English)

Cunwen WANG; Chuanbo YU; Wen CHEN; Weiguo WANG; Yuanxin WU; Junfeng ZHANG

2008-01-01

The partial molar volumes of components in supercritical ammonia synthesis system are calculated in detail by the calculation formula of partial molar volume derived from the R-K equation of state under different conditions. The objectives are to comprehend phase beha-vior of components and to provide the theoretic explana-tion and guidance for probing novel processes of ammonia synthesis under supercritical conditions. The conditions of calculation are H2/N2= 3, at a concentra-tion of NH3 in synthesis gas ranging from 2% to 15%, Concentration of medium in supercritical ammonia syn-thesis system ranging from 20% to 50%, temperature ran-ging from 243 K to 699 K and pressure ranging from 0.1 MPa to 187 MPa. The results show that the ammonia synthesis system can reach supercritical state by adding a suitable supercritical medium and then controlling the reaction conditions. It is helpful for the supercritical ammonia synthesis that medium reaches supercritical state under the conditions of the corresponding total pres-sure and components near the normal temperature or near the critical temperature of medium or in the range of tem-perature of industrialized ammonia synthesis.

Improvement of the Cubic Spline Function Sets for a Synthesis of the Axial Power Distribution of a Core Protection System

International Nuclear Information System (INIS)

Koo, Bon-Seung; Lee, Chung-Chan; Zee, Sung-Quun

2006-01-01

Online digital core protection system(SCOPS) for a system-integrated modular reactor is being developed as a part of a plant protection system at KAERI. SCOPS calculates the minimum CHFR and maximum LPD based on several online measured system parameters including 3-level ex-core detector signals. In conventional ABB-CE digital power plants, cubic spline synthesis technique has been used in online calculations of the core axial power distributions using ex-core detector signals once every 1 second in CPC. In CPC, pre-determined cubic spline function sets are used depending on the characteristics of the ex-core detector responses. But this method shows an unnegligible power distribution error for the extremely skewed axial shapes by using restrictive function sets. Therefore, this paper describes the cubic spline method for the synthesis of an axial power distribution and it generates several new cubic spline function sets for the application of the core protection system, especially for the severely distorted power shapes needed reactor type

Deoxynivalenol affects in vitro intestinal epithelial cell barrier integrity through inhibition of protein synthesis

International Nuclear Information System (INIS)

Van De Walle, Jacqueline; Sergent, Therese; Piront, Neil; Toussaint, Olivier; Schneider, Yves-Jacques; Larondelle, Yvan

2010-01-01

Deoxynivalenol (DON), one of the most common mycotoxin contaminants of raw and processed cereal food, adversely affects the gastrointestinal tract. Since DON acts as a protein synthesis inhibitor, the constantly renewing intestinal epithelium could be particularly sensitive to DON. We analyzed the toxicological effects of DON on intestinal epithelial protein synthesis and barrier integrity. Differentiated Caco-2 cells, as a widely used model of the human intestinal barrier, were exposed to realistic intestinal concentrations of DON (50, 500 and 5000 ng/ml) during 24 h. DON caused a concentration-dependent decrease in total protein content associated with a reduction in the incorporation of [ 3 H]-leucine, demonstrating its inhibitory effect on protein synthesis. DON simultaneously increased the paracellular permeability of the monolayer as reflected through a decreased transepithelial electrical resistance associated with an increased paracellular flux of the tracer [ 3 H]-mannitol. A concentration-dependent reduction in the expression level of the tight junction constituent claudin-4 was demonstrated by Western blot, which was not due to diminished transcription, increased degradation, or NF-κB, ERK or JNK activation, and was also observed for a tight junction independent protein, i.e. intestinal alkaline phosphatase. These results demonstrate a dual toxicological effect of DON on differentiated Caco-2 cells consisting in an inhibition of protein synthesis as well as an increase in monolayer permeability, and moreover suggest a possible link between them through diminished synthesis of the tight junction constituent claudin-4.

Systems Integration Fact Sheet

Energy Technology Data Exchange (ETDEWEB)

None

2016-06-01

This fact sheet is an overview of the Systems Integration subprogram at the U.S. Department of Energy SunShot Initiative. The Systems Integration subprogram enables the widespread deployment of safe, reliable, and cost-effective solar energy technologies by addressing the associated technical and non-technical challenges. These include timely and cost-effective interconnection procedures, optimal system planning, accurate prediction of solar resources, monitoring and control of solar power, maintaining grid reliability and stability, and many more. To address the challenges associated with interconnecting and integrating hundreds of gigawatts of solar power onto the electricity grid, the Systems Integration program funds research, development, and demonstration projects in four broad, interrelated focus areas: grid performance and reliability, dispatchability, power electronics, and communications.

Network analysis and synthesis a modern systems theory approach

CERN Document Server

Anderson, Brian D O

2006-01-01

Geared toward upper-level undergraduates and graduate students, this book offers a comprehensive look at linear network analysis and synthesis. It explores state-space synthesis as well as analysis, employing modern systems theory to unite the classical concepts of network theory. The authors stress passive networks but include material on active networks. They avoid topology in dealing with analysis problems and discuss computational techniques. The concepts of controllability, observability, and degree are emphasized in reviewing the state-variable description of linear systems. Explorations

The systems integration modeling system

International Nuclear Information System (INIS)

Danker, W.J.; Williams, J.R.

1990-01-01

This paper discusses the systems integration modeling system (SIMS), an analysis tool for the detailed evaluation of the structure and related performance of the Federal Waste Management System (FWMS) and its interface with waste generators. It's use for evaluations in support of system-level decisions as to FWMS configurations, the allocation, sizing, balancing and integration of functions among elements, and the establishment of system-preferred waste selection and sequencing methods and other operating strategies is presented. SIMS includes major analysis submodels which quantify the detailed characteristics of individual waste items, loaded casks and waste packages, simulate the detailed logistics of handling and processing discrete waste items and packages, and perform detailed cost evaluations

Fuels planning: science synthesis and integration; environmental consequences fact sheet 05: prescriptions and fire effects

Science.gov (United States)

Melanie Miller

2004-01-01

Fuels planning: science synthesis and integration; environmental consequences fact sheet 5: prescriptions and fire effects. Miller, Melanie. 2004. Res. Note RMRS-RN-23-5-WWW. Fort Collins, CO: U.S. Department of Agriculture, Forest Service, Rocky Mountain Research Station. 2 p. While our understanding of the causes for variation in postfire effects is increasing, burn...

Ion transport membrane reactor systems and methods for producing synthesis gas

Science.gov (United States)

Repasky, John Michael

2015-05-12

Embodiments of the present invention provide cost-effective systems and methods for producing a synthesis gas product using a steam reformer system and an ion transport membrane (ITM) reactor having multiple stages, without requiring inter-stage reactant injections. Embodiments of the present invention also provide techniques for compensating for membrane performance degradation and other changes in system operating conditions that negatively affect synthesis gas production.

Synthesis for Structure Rewriting Systems

Science.gov (United States)

Kaiser, Łukasz

The description of a single state of a modelled system is often complex in practice, but few procedures for synthesis address this problem in depth. We study systems in which a state is described by an arbitrary finite structure, and changes of the state are represented by structure rewriting rules, a generalisation of term and graph rewriting. Both the environment and the controller are allowed to change the structure in this way, and the question we ask is how a strategy for the controller that ensures a given property can be synthesised.

Systems integration (automation system). System integration (automation system)

Energy Technology Data Exchange (ETDEWEB)

Fujii, K; Komori, T; Fukuma, Y; Oikawa, M [Nippon Steal Corp., Tokyo (Japan)

1991-09-26

This paper introduces business activities on an automation systems integration (SI) started by a company in July,1988, and describes the SI concepts. The business activities include, with the CIM (unified production carried out on computers) and AMENITY (living environment) as the mainstays, a single responsibility construction ranging from consultation on structuring optimal systems for processing and assembling industries and intelligent buildings to system design, installation and after-sales services. With an SI standing on users {prime} position taken most importantly, the business starts from a planning and consultation under close coordination. On the conceptual basis of structuring optimal systems using the ompany {prime}s affluent know-hows and tools and adapting and applying with multi-vendors, open networks, centralized and distributed systems, the business is promoted with the accumulated technologies capable of realizing artificial intelligence and neural networks in its background, and supported with highly valuable business results in the past. 10 figs., 1 tab.

On synthesis and optimization of steam system networks. 1. Sustained boiler efficiency

CSIR Research Space (South Africa)

Majozi, T

2010-08-01

Full Text Available situations. This paper presents a process integration technique for network synthesis using conceptual and mathematical analysis without compromising boiler efficiency. It was found that the steam flow rate to the HEN could be reduced while maintaining boiler...

Synthesis of qualitative linguistic research--a pilot review integrating and generalizing findings on doctor-patient interaction.

Science.gov (United States)

Nowak, Peter

2011-03-01

There is a broad range qualitative linguistic research (sequential analysis) on doctor-patient interaction that had only a marginal impact on clinical research and practice. At least in parts this is due to the lack of qualitative research synthesis in the field. Available research summaries are not systematic in their methodology. This paper proposes a synthesis methodology for qualitative, sequential analytic research on doctor-patient interaction. The presented methodology is not new but specifies standard methodology of qualitative research synthesis for sequential analytic research. This pilot review synthesizes twelve studies on German-speaking doctor-patient interactions, identifies 45 verbal actions of doctors and structures them in a systematics of eight interaction components. Three interaction components ("Listening", "Asking for information", and "Giving information") seem to be central and cover two thirds of the identified action types. This pilot review demonstrates that sequential analytic research can be synthesized in a consistent and meaningful way, thus providing a more comprehensive and unbiased integration of research. Future synthesis of qualitative research in the area of health communication research is very much needed. Qualitative research synthesis can support the development of quantitative research and of educational materials in medical training and patient training. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

Control synthesis of switched systems

CERN Document Server

Zhao, Xudong; Niu, Ben; Wu, Tingting

2017-01-01

This book offers its readers a detailed overview of the synthesis of switched systems, with a focus on switching stabilization and intelligent control. The problems investigated are not only previously unsolved theoretically but also of practical importance in many applications: voltage conversion, naval piloting and navigation and robotics, for example. The book considers general switched-system models and provides more efficient design methods to bring together theory and application more closely than was possible using classical methods. It also discusses several different classes of switched systems. For general switched linear systems and switched nonlinear systems comprising unstable subsystems, it introduces novel ideas such as invariant subspace theory and the time-scheduled Lyapunov function method of designing switching signals to stabilize the underlying systems. For some typical switched nonlinear systems affected by various complex dynamics, the book proposes novel design approaches based on inte...

Passivity analysis and synthesis for uncertain time-delay systems

Directory of Open Access Journals (Sweden)

Magdi S. Mahmoud

2001-01-01

Full Text Available In this paper, we investigate the robust passivity analysis and synthesis problems for a class of uncertain time-delay systems. This class of systems arises in the modelling effort of studying water quality constituents in fresh stream. For the analysis problem, we derive a sufficient condition for which the uncertain time-delay system is robustly stable and strictly passive for all admissible uncertainties. The condition is given in terms of a linear matrix inequality. Both the delay-independent and delay-dependent cases are considered. For the synthesis problem, we propose an observer-based design method which guarantees that the closed-loop uncertain time-delay system is stable and strictly passive for all admissible uncertainties. Several examples are worked out to illustrate the developed theory.

Analysis and Synthesis of Communication-Intensive Heterogeneous Real-Time Systems

DEFF Research Database (Denmark)

Pop, Paul

2003-01-01

Embedded computer systems are now everywhere: from alarm clocks to PDAs, from mobile phones to cars, almost all the devices we use are controlled by embedded computer systems. An important class of embedded computer systems is that of real-time systems, which have to fulfill strict timing...... requirements. As realtime systems become more complex, they are often implemented using distributed heterogeneous architectures. The main objective of this thesis is to develop analysis and synthesis methods for communication-intensive heterogeneous hard real-time systems. The systems are heterogeneous...... is the synthesis of the communication infrastructure, which has a significant impact on the overall system performance and cost. To reduce the time-to-market of products, the design of real-time systems seldom starts from scratch. Typically, designers start from an already existing system, running certain...

Systems integration processes for space nuclear electric propulsion systems

International Nuclear Information System (INIS)

Olsen, C.S.; Rice, J.W.; Stanley, M.L.

1991-01-01

The various components and subsystems that comprise a nuclear electric propulsion system should be developed and integrated so that each functions ideally and so that each is properly integrated with the other components and subsystems in the optimum way. This paper discusses how processes similar to those used in the development and intergration of the subsystems that comprise the Multimegawatt Space Nuclear Power System concepts can be and are being efficiently and effectively utilized for these purposes. The processes discussed include the development of functional and operational requirements at the system and subsystem level; the assessment of individual nuclear power supply and thruster concepts and their associated technologies; the conduct of systems integration efforts including the evaluation of the mission benefits for each system; the identification and resolution of concepts development, technology development, and systems integration feasibility issues; subsystem, system, and technology development and integration; and ground and flight subsystem and integrated system testing

Geometry and dynamics of integrable systems

CERN Document Server

Matveev, Vladimir

2016-01-01

Based on lectures given at an advanced course on integrable systems at the Centre de Recerca Matemàtica in Barcelona, these lecture notes address three major aspects of integrable systems: obstructions to integrability from differential Galois theory; the description of singularities of integrable systems on the basis of their relation to bi-Hamiltonian systems; and the generalization of integrable systems to the non-Hamiltonian settings. All three sections were written by top experts in their respective fields. Native to actual problem-solving challenges in mechanics, the topic of integrable systems is currently at the crossroads of several disciplines in pure and applied mathematics, and also has important interactions with physics. The study of integrable systems also actively employs methods from differential geometry. Moreover, it is extremely important in symplectic geometry and Hamiltonian dynamics, and has strong correlations with mathematical physics, Lie theory and algebraic geometry (including mir...

Control system integration

CERN Document Server

Shea, T J

2008-01-01

This lecture begins with a definition of an accelerator control system, and then reviews the control system architectures that have been deployed at the larger accelerator facilities. This discussion naturally leads to identification of the major subsystems and their interfaces. We shall explore general strategies for integrating intelligent devices and signal processing subsystems based on gate arrays and programmable DSPs. The following topics will also be covered: physical packaging; timing and synchronization; local and global communication technologies; interfacing to machine protection systems; remote debugging; configuration management and source code control; and integration of commercial software tools. Several practical realizations will be presented.

Integrated RIS-PACS system

International Nuclear Information System (INIS)

Nishihara, Eitaro; Kura, Hiroyuki; Fukushima, Yuki

1994-01-01

We have developed an integrated RIS-PACS (radiology information system-picture archiving and communication system) system which supports examination, interpretation, and management in the diagnostic imaging department. The system was introduced in the Toshiba Hospital in May 1993, concurrently with the renewal of the hospital facilities. The integrated RIS-PACS system consists of a radiology information management system, and an image management system. The system supports wet (immediate) reading and chronological comparative reading using viewing workstation, enables routine operations to be performed in the diagnostic imaging department without film transportation, and contributes to the improvement of management efficiency in the department. (author)

Temperature lowering in cryogenic chemical-synthesis techniques and system

International Nuclear Information System (INIS)

Martinez, H.E.; Nelson, T.O.; Vikdal, L.N.

1993-01-01

When evaluating a chemical synthesis process for a reaction that occurs on the cryogenically cooled walls, it is sometimes necessary to reduce the wall temperatures to enhance the chemical process. To evaluate the chemical process at lower than atmospheric boiling of liquid nitrogen, we built a system and used it to reduce the temperature of the liquid nitrogen. The technique of lowering the liquid nitrogen temperature by reducing the pressure of the boil-off is established knowledge. This paper presents the engineering aspects of the system, design features, equipment requirements, methods of control, and results of the chemical synthesis. The heat input to the system was ∼400 watts, placing a relatively large demand on the pumping system. Our system is a scale-up of the small laboratory experiment, and it provides the information needed to design an effective system. The major problem encountered was the large quantity of liquid escaping the system during the processing, placing a large gas load on the vacuum system

What Synthesis Methodology Should I Use? A Review and Analysis of Approaches to Research Synthesis.

Science.gov (United States)

Schick-Makaroff, Kara; MacDonald, Marjorie; Plummer, Marilyn; Burgess, Judy; Neander, Wendy

2016-01-01

When we began this process, we were doctoral students and a faculty member in a research methods course. As students, we were facing a review of the literature for our dissertations. We encountered several different ways of conducting a review but were unable to locate any resources that synthesized all of the various synthesis methodologies. Our purpose is to present a comprehensive overview and assessment of the main approaches to research synthesis. We use 'research synthesis' as a broad overarching term to describe various approaches to combining, integrating, and synthesizing research findings. We conducted an integrative review of the literature to explore the historical, contextual, and evolving nature of research synthesis. We searched five databases, reviewed websites of key organizations, hand-searched several journals, and examined relevant texts from the reference lists of the documents we had already obtained. We identified four broad categories of research synthesis methodology including conventional, quantitative, qualitative, and emerging syntheses. Each of the broad categories was compared to the others on the following: key characteristics, purpose, method, product, context, underlying assumptions, unit of analysis, strengths and limitations, and when to use each approach. The current state of research synthesis reflects significant advancements in emerging synthesis studies that integrate diverse data types and sources. New approaches to research synthesis provide a much broader range of review alternatives available to health and social science students and researchers.

Thermal Distribution System | Energy Systems Integration Facility | NREL

Science.gov (United States)

Thermal Distribution System Thermal Distribution System The Energy Systems Integration Facility's . Photo of the roof of the Energy Systems Integration Facility. The thermal distribution bus allows low as 10% of its full load level). The 60-ton chiller cools water with continuous thermal control

QUANTITATIVE СHARACTERISTICS OF COMPLEMENTARY INTEGRATED HEALTH CARE SYSTEM AND INTEGRATED MEDICATION MANAGEMENT INFORMATION SYSTEM

Directory of Open Access Journals (Sweden)

L. Yu. Babintseva

2015-05-01

i mportant elements of state regulation of the pharmaceutical sector health. For the first time creation of two information systems: integrated medication management infor mation system and integrated health care system in an integrated medical infor mation area, operating based on th e principle of complementarity was justified. Global and technological coefficients of these systems’ functioning were introduced.

Preparation of ubiquitin-conjugated proteins using an insect cell-free protein synthesis system.

Science.gov (United States)

Suzuki, Takashi; Ezure, Toru; Ando, Eiji; Nishimura, Osamu; Utsumi, Toshihiko; Tsunasawa, Susumu

2010-01-01

Ubiquitination is one of the most significant posttranslational modifications (PTMs). To evaluate the ability of an insect cell-free protein synthesis system to carry out ubiquitin (Ub) conjugation to in vitro translated proteins, poly-Ub chain formation was studied in an insect cell-free protein synthesis system. Poly-Ub was generated in the presence of Ub aldehyde (UA), a de-ubiquitinating enzyme inhibitor. In vitro ubiquitination of the p53 tumor suppressor protein was also analyzed, and p53 was poly-ubiquitinated when Ub, UA, and Mdm2, an E3 Ub ligase (E3) for p53, were added to the in vitro reaction mixture. These results suggest that the insect cell-free protein synthesis system contains enzymatic activities capable of carrying out ubiquitination. CBB-detectable ubiquitinated p53 was easily purified from the insect cell-free protein synthesis system, allowing analysis of the Ub-conjugated proteins by mass spectrometry (MS). Lys 305 of p53 was identified as one of the Ub acceptor sites using this strategy. Thus, we conclude that the insect cell-free protein synthesis system is a powerful tool for studying various PTMs of eukaryotic proteins including ubiqutination presented here.

Synthesis of Fault-Tolerant Embedded Systems

DEFF Research Database (Denmark)

Eles, Petru; Izosimov, Viacheslav; Pop, Paul

2008-01-01

This work addresses the issue of design optimization for fault- tolerant hard real-time systems. In particular, our focus is on the handling of transient faults using both checkpointing with rollback recovery and active replication. Fault tolerant schedules are generated based on a conditional...... process graph representation. The formulated system synthesis approaches decide the assignment of fault-tolerance policies to processes, the optimal placement of checkpoints and the mapping of processes to processors, such that multiple transient faults are tolerated, transparency requirements...

Integration of reusable systems

CERN Document Server

Rubin, Stuart

2014-01-01

Software reuse and integration has been described as the process of creating software systems from existing software rather than building software systems from scratch. Whereas reuse solely deals with the artifacts creation, integration focuses on how reusable artifacts interact with the already existing parts of the specified transformation. Currently, most reuse research focuses on creating and integrating adaptable components at development or at compile time. However, with the emergence of ubiquitous computing, reuse technologies that can support adaptation and reconfiguration of architectures and components at runtime are in demand. This edited book includes 15 high quality research papers written by experts in information reuse and integration to cover the most recent advances in the field. These papers are extended versions of the best papers which were presented at IEEE International Conference on Information Reuse and Integration and IEEE International Workshop on Formal Methods Integration, which wa...

Challenges and opportunities in integration of design and control

DEFF Research Database (Denmark)

Huusom, Jakob Kjøbsted

2015-01-01

Process synthesis and design of plant operation are related topics but current industrial practice solves these problems sequentially. The implication of this sequential strategy may result in design of processing systems which are very hard to control. This paper presents a discussion on drivers...... for an integrated approach and outlines the challenges in formulation of such a multi-objective synthesis problem. This discussion is viewed in relation to some of the changing trends in the industry. Significant results have been published which in different ways seek to handle the integrated problem. Further...

SUBSURFACE REPOSITORY INTEGRATED CONTROL SYSTEM DESIGN

International Nuclear Information System (INIS)

Randle, D.C.

2000-01-01

The primary purpose of this document is to develop a preliminary high-level functional and physical control system architecture for the potential repository at Yucca Mountain. This document outlines an overall control system concept that encompasses and integrates the many diverse process and communication systems being developed for the subsurface repository design. This document presents integrated design concepts for monitoring and controlling the diverse set of subsurface operations. The Subsurface Repository Integrated Control System design will be composed of a series of diverse process systems and communication networks. The subsurface repository design contains many systems related to instrumentation and control (I andC) for both repository development and waste emplacement operations. These systems include waste emplacement, waste retrieval, ventilation, radiological and air monitoring, rail transportation, construction development, utility systems (electrical, lighting, water, compressed air, etc.), fire protection, backfill emplacement, and performance confirmation. Each of these systems involves some level of I andC and will typically be integrated over a data communications network throughout the subsurface facility. The subsurface I andC systems will also interface with multiple surface-based systems such as site operations, rail transportation, security and safeguards, and electrical/piped utilities. In addition to the I andC systems, the subsurface repository design also contains systems related to voice and video communications. The components for each of these systems will be distributed and linked over voice and video communication networks throughout the subsurface facility. The scope and primary objectives of this design analysis are to: (1) Identify preliminary system-level functions and interfaces (Section 6.2). (2) Examine the overall system complexity and determine how and on what levels the engineered process systems will be monitored

Tactical Systems Integration Laboratory

Data.gov (United States)

Federal Laboratory Consortium — The Tactical Systems Integration Laboratory is used to design and integrate computer hardware and software and related electronic subsystems for tactical vehicles....

Function integrated track system

OpenAIRE

Hohnecker, Eberhard

2010-01-01

The paper discusses a function integrated track system that focuses on the reduction of acoustic emissions from railway lines. It is shown that the combination of an embedded rail system (ERS), a sound absorbing track surface, and an integrated mini sound barrier has significant acoustic advantages compared to a standard ballast superstructure. The acoustic advantages of an embedded rail system are particularly pronounced in the case of railway bridges. Finally, it is shown that a...

Smart systems integration and simulation

CERN Document Server

Poncino, Massimo; Pravadelli, Graziano

2016-01-01

This book-presents new methods and tools for the integration and simulation of smart devices. The design approach described in this book explicitly accounts for integration of Smart Systems components and subsystems as a specific constraint. It includes methodologies and EDA tools to enable multi-disciplinary and multi-scale modeling and design, simulation of multi-domain systems, subsystems and components at all levels of abstraction, system integration and exploration for optimization of functional and non-functional metrics. By covering theoretical and practical aspects of smart device design, this book targets people who are working and studying on hardware/software modelling, component integration and simulation under different positions (system integrators, designers, developers, researchers, teachers, students etc.). In particular, it is a good introduction to people who have interest in managing heterogeneous components in an efficient and effective way on different domains and different abstraction l...

Bond graphs : an integrating tool for design of mechatronic systems

International Nuclear Information System (INIS)

Ould Bouamama, B.

2011-01-01

Bond graph is a powerful tool well known for dynamic modelling of multi physical systems: This is the only modelling technique to generate automatically state space or non-linear models using dedicated software tools (CAMP-G, 20-Sim, Symbols, Dymola...). Recently several fundamental theories have been developed for using a bond graph model not only for modeling but also as a real integrated tool from conceptual ideas to optimal practical realization of mechatronic system. This keynote presents a synthesis of those new theories which exploit some particular properties (such as causal, structural and behavioral) of this graphical methodology. Based on a pedagogical example, it will be shown how from a physical system (not a transfer function or state equation) and using only one representation (Bond graph), the following results can be performed: modeling (formal state equations generation), Control analysis (observability, controllability, Structural I/O decouplability, dynamic decoupling,...) diagnosis analysis (automatic generation of robust fault indicators, sensor placement, structural diagnosability) and finally sizing of actuators. The presentation will be illustrated by real industrial applications. Limits and perspectives of bond graph theory conclude the keynote.

Management of radioactive waste gases from PET radiopharmaceutical synthesis using cost effective capture systems integrated with a cyclotron safety system.

Science.gov (United States)

Stimson, D H R; Pringle, A J; Maillet, D; King, A R; Nevin, S T; Venkatachalam, T K; Reutens, D C; Bhalla, R

2016-09-01

The emphasis on the reduction of gaseous radioactive effluent associated with PET radiochemistry laboratories has increased. Various radioactive gas capture strategies have been employed historically including expensive automated compression systems. We have implemented a new cost-effective strategy employing gas capture bags with electronic feedback that are integrated with the cyclotron safety system. Our strategy is suitable for multiple automated 18 F radiosynthesis modules and individual automated 11 C radiosynthesis modules. We describe novel gas capture systems that minimize the risk of human error and are routinely used in our facility.

Energy Systems Integration News | Energy Systems Integration Facility |

Science.gov (United States)

, utilities can operate more efficiently and profitably. That can increase the use of renewable energy sources challenge to utility companies, grid operators, and other stakeholders involved in wind energy integration recording is available from the July 16 webinar "Smart Grid Research at NREL's Energy Systems

Facial fluid synthesis for assessment of acne vulgaris using luminescent visualization system through optical imaging and integration of fluorescent imaging system

Science.gov (United States)

Balbin, Jessie R.; Dela Cruz, Jennifer C.; Camba, Clarisse O.; Gozo, Angelo D.; Jimenez, Sheena Mariz B.; Tribiana, Aivje C.

2017-06-01

Acne vulgaris, commonly called as acne, is a skin problem that occurs when oil and dead skin cells clog up in a person's pores. This is because hormones change which makes the skin oilier. The problem is people really do not know the real assessment of sensitivity of their skin in terms of fluid development on their faces that tends to develop acne vulgaris, thus having more complications. This research aims to assess Acne Vulgaris using luminescent visualization system through optical imaging and integration of image processing algorithms. Specifically, this research aims to design a prototype for facial fluid analysis using luminescent visualization system through optical imaging and integration of fluorescent imaging system, and to classify different facial fluids present in each person. Throughout the process, some structures and layers of the face will be excluded, leaving only a mapped facial structure with acne regions. Facial fluid regions are distinguished from the acne region as they are characterized differently.

Duality for discrete integrable systems

International Nuclear Information System (INIS)

Quispel, G R W; Capel, H W; Roberts, J A G

2005-01-01

A new class of discrete dynamical systems is introduced via a duality relation for discrete dynamical systems with a number of explicitly known integrals. The dual equation can be defined via the difference of an arbitrary linear combination of integrals and its upshifted version. We give an example of an integrable mapping with two parameters and four integrals leading to a (four-dimensional) dual mapping with four parameters and two integrals. We also consider a more general class of higher-dimensional mappings arising via a travelling-wave reduction from the (integrable) MKdV partial-difference equation. By differencing the trace of the monodromy matrix we obtain a class of novel dual mappings which is shown to be integrable as level-set-dependent versions of the original ones

Synthesis Methods, Microscopy Characterization and Device Integration of Nanoscale Metal Oxide Semiconductors for Gas Sensing in Aerospace Applications

Science.gov (United States)

VanderWal, Randy L.; Berger, Gordon M.; Kulis, Michael J.; Hunter, Gary W.; Xu, Jennifer C.; Evans, Laura J.

2009-01-01

A comparison is made between SnO2, ZnO, and TiO2 single-crystal nanowires and SnO2 polycrystalline nanofibers for gas sensing. Both nanostructures possess a one-dimensional morphology. Different synthesis methods are used to produce these materials: thermal evaporation-condensation (TEC), controlled oxidation, and electrospinning. Advantages and limitations of each technique are listed. Practical issues associated with harvesting, purification, and integration of these materials into sensing devices are detailed. For comparison to the nascent form, these sensing materials are surface coated with Pd and Pt nanoparticles. Gas sensing tests, with respect to H2, are conducted at ambient and elevated temperatures. Comparative normalized responses and time constants for the catalyst and noncatalyst systems provide a basis for identification of the superior metal-oxide nanostructure and catalyst combination. With temperature-dependent data, Arrhenius analyses are made to determine an activation energy for the catalyst-assisted systems.

Agents in an Integrated System Architecture

DEFF Research Database (Denmark)

Hartvig, Susanne C; Andersen, Tom

1997-01-01

This paper presents research findings from development of an expert system and its integration into an integrated environment. Expert systems has proven hard to integrate because of their interactive nature. A prototype environment was developed using new integration technologies, and research...... findings concerning the use of OLE technology to integrate stand alone applications are discussed. The prototype shows clear advantages of using OLE technology when developing integrated environments....

Performance analysis of an integrated biomass gasification and PEMFC (proton exchange membrane fuel cell) system: Hydrogen and power generation

International Nuclear Information System (INIS)

Chutichai, Bhawasut; Authayanun, Suthida; Assabumrungrat, Suttichai; Arpornwichanop, Amornchai

2013-01-01

The PEMFC (proton exchange membrane fuel cell) is expected to play a significant role in next-generation energy systems. Because most hydrogen that is used as a fuel for PEMFCs is derived from the reforming of natural gas, the use of renewable energy sources such as biomass to produce this hydrogen offers a promising alternative. This study is focused on the performance analysis of an integrated biomass gasification and PEMFC system. The combined heat and power generation output of this integrated system is designed for residential applications, taking into account thermal and electrical demands. A flowsheet model of the integrated PEMFC system is developed and employed to analyze its performance with respect to various key operating parameters. A purification process consisting of a water–gas shift reactor and a preferential oxidation reactor is also necessary in order to reduce the concentration of CO in the synthesis gas to below 10 ppm for subsequent use in the PEMFC. The effect of load level on the performance of the PEMFC system is investigated. Based on an electrical load of 5 kW, it is found that the electrical efficiency of the PEMFC integrated system is 22%, and, when waste heat recovery is considered, the total efficiency of the PEMFC system is 51%. - Highlights: • Performance of a biomass gasification and PEMFC integrated system is analyzed. • A flowsheet model of the PEMFC integrated system is developed. • Effect of biomass sources and key parameters on hydrogen and power generation is presented. • The PEMFC integrated system is designed for small-scale power demand. • Effect of load changes on the performance of PEMFC is investigated

SUBSURFACE REPOSITORY INTEGRATED CONTROL SYSTEM DESIGN

International Nuclear Information System (INIS)

C.J. Fernado

1998-01-01

The purpose of this document is to develop preliminary high-level functional and physical control system architectures for the proposed subsurface repository at Yucca Mountain. This document outlines overall control system concepts that encompass and integrate the many diverse systems being considered for use within the subsurface repository. This document presents integrated design concepts for monitoring and controlling the diverse set of subsurface operations. The subsurface repository design will be composed of a series of diverse systems that will be integrated to accomplish a set of overall functions and objectives. The subsurface repository contains several Instrumentation and Control (I andC) related systems including: waste emplacement systems, ventilation systems, communication systems, radiation monitoring systems, rail transportation systems, ground control monitoring systems, utility monitoring systems (electrical, lighting, water, compressed air, etc.), fire detection and protection systems, retrieval systems, and performance confirmation systems. Each of these systems involve some level of I andC and will typically be integrated over a data communication network. The subsurface I andC systems will also integrate with multiple surface-based site-wide systems such as emergency response, health physics, security and safeguards, communications, utilities and others. The scope and primary objectives of this analysis are to: (1) Identify preliminary system level functions and interface needs (Presented in the functional diagrams in Section 7.2). (2) Examine the overall system complexity and determine how and on what levels these control systems will be controlled and integrated (Presented in Section 7.2). (3) Develop a preliminary subsurface facility-wide design for an overall control system architecture, and depict this design by a series of control system functional block diagrams (Presented in Section 7.2). (4) Develop a series of physical architectures

SUBSURFACE REPOSITORY INTEGRATED CONTROL SYSTEM DESIGN

Energy Technology Data Exchange (ETDEWEB)

C.J. Fernado

1998-09-17

The purpose of this document is to develop preliminary high-level functional and physical control system architectures for the proposed subsurface repository at Yucca Mountain. This document outlines overall control system concepts that encompass and integrate the many diverse systems being considered for use within the subsurface repository. This document presents integrated design concepts for monitoring and controlling the diverse set of subsurface operations. The subsurface repository design will be composed of a series of diverse systems that will be integrated to accomplish a set of overall functions and objectives. The subsurface repository contains several Instrumentation and Control (I&C) related systems including: waste emplacement systems, ventilation systems, communication systems, radiation monitoring systems, rail transportation systems, ground control monitoring systems, utility monitoring systems (electrical, lighting, water, compressed air, etc.), fire detection and protection systems, retrieval systems, and performance confirmation systems. Each of these systems involve some level of I&C and will typically be integrated over a data communication network. The subsurface I&C systems will also integrate with multiple surface-based site-wide systems such as emergency response, health physics, security and safeguards, communications, utilities and others. The scope and primary objectives of this analysis are to: (1) Identify preliminary system level functions and interface needs (Presented in the functional diagrams in Section 7.2). (2) Examine the overall system complexity and determine how and on what levels these control systems will be controlled and integrated (Presented in Section 7.2). (3) Develop a preliminary subsurface facility-wide design for an overall control system architecture, and depict this design by a series of control system functional block diagrams (Presented in Section 7.2). (4) Develop a series of physical architectures that

Confidentiality and integrity in crowdsourcing systems

CERN Document Server

Ranj Bar, Amin

2014-01-01

Confidentiality and Integrity in Crowdsourcing Systems focuses on identity, privacy, and security related issues in crowdsourcing systems and in particular the confidentiality and integrity of online data created via crowdsourcing. This book begins with an introduction to crowdsourcing and then covers the privacy and security challenges of Confidentiality. The book examines integrity in these systems and the management and control of crowdsourcing systems.

A multi-paradigm language for reactive synthesis

Directory of Open Access Journals (Sweden)

Ioannis Filippidis

2016-02-01

Full Text Available This paper proposes a language for describing reactive synthesis problems that integrates imperative and declarative elements. The semantics is defined in terms of two-player turn-based infinite games with full information. Currently, synthesis tools accept linear temporal logic (LTL as input, but this description is less structured and does not facilitate the expression of sequential constraints. This motivates the use of a structured programming language to specify synthesis problems. Transition systems and guarded commands serve as imperative constructs, expressed in a syntax based on that of the modeling language Promela. The syntax allows defining which player controls data and control flow, and separating a program into assumptions and guarantees. These notions are necessary for input to game solvers. The integration of imperative and declarative paradigms allows using the paradigm that is most appropriate for expressing each requirement. The declarative part is expressed in the LTL fragment of generalized reactivity(1, which admits efficient synthesis algorithms, extended with past LTL. The implementation translates Promela to input for the Slugs synthesizer and is written in Python. The AMBA AHB bus case study is revisited and synthesized efficiently, identifying the need to reorder binary decision diagrams during strategy construction, in order to prevent the exponential blowup observed in previous work.

Schedulability-Driven Communication Synthesis for Time Triggered Embedded Systems

DEFF Research Database (Denmark)

Pop, Paul; Eles, Petru; Peng, Zebo

2006-01-01

We present an approach to static priority preemptive process scheduling for the synthesis of hard real-time distributed embedded systems where communication plays an important role. The communication model is based on a time-triggered protocol. We have developed an analysis for the communication...... delays proposing four different message scheduling policies over a time-triggered communication channel. Optimization strategies for the synthesis of communication are developed, and the four approaches to message scheduling are compared using extensive experiments...

Schedulability-Driven Communication Synthesis for Time Triggered Embedded Systems

DEFF Research Database (Denmark)

Pop, Paul; Eles, Petru; Peng, Zebo

1999-01-01

We present an approach to static priority preemptive process scheduling for the synthesis of hard real-time distributed embedded systems where communication plays an important role. The communication model is based on a time-triggered protocol. We have developed an analysis for the communication...... delays proposing four different message scheduling policies over a time-triggered communication channel. Optimization strategies for the synthesis of communication are developed, and the four approaches to message scheduling are compared using extensive experiments....

Schedulability-Driven Communication Synthesis for Time Triggered Embedded Systems

DEFF Research Database (Denmark)

Pop, Paul; Eles, Petru; Peng, Zebo

2004-01-01

We present an approach to static priority preemptive process scheduling for the synthesis of hard real-time distributed embedded systems where communication plays an important role. The communication model is based on a time-triggered protocol. We have developed an analysis for the communication...... delays with four different message scheduling policies over a time-triggered communication channel. Optimization strategies for the synthesis of communication are developed, and the four approaches to message scheduling are compared using extensive experiments....

A Transcriptomic Analysis of Xylan Mutants Does Not Support the Existence of a Secondary Cell Wall Integrity System in Arabidopsis.

Science.gov (United States)

Faria-Blanc, Nuno; Mortimer, Jenny C; Dupree, Paul

2018-01-01

Yeast have long been known to possess a cell wall integrity (CWI) system, and recently an analogous system has been described for the primary walls of plants (PCWI) that leads to changes in plant growth and cell wall composition. A similar system has been proposed to exist for secondary cell walls (SCWI). However, there is little data to support this. Here, we analyzed the stem transcriptome of a set of cell wall biosynthetic mutants in order to investigate whether cell wall damage, in this case caused by aberrant xylan synthesis, activates a signaling cascade or changes in cell wall synthesis gene expression. Our data revealed remarkably few changes to the transcriptome. We hypothesize that this is because cells undergoing secondary cell wall thickening have entered a committed programme leading to cell death, and therefore a SCWI system would have limited impact. The absence of transcriptomic responses to secondary cell wall alterations may facilitate engineering of the secondary cell wall of plants.

An integrated environment of software development and V and V for PLC based safety-critical systems

International Nuclear Information System (INIS)

Koo, Seo Ryong

2005-02-01

To develop and implement a safety-critical system, the requirements of the system must be analyzed thoroughly during the phases of a software development's life cycle because a single error in the requirements can generate serious software faults. We therefore propose an Integrated Environment (IE) approach for requirements which is an integrated approach that enables easy inspection by combining requirement traceability and effective use of a formal method. For the V and V tasks of requirements phase, our approach uses software inspection, requirement traceability, and formal specification with structural decomposition. Software inspection and the analysis of requirements traceability are the most effective methods of software V and V. Although formal methods are also considered an effective V and V activity, they are difficult to use properly in nuclear fields, as well as in other fields, because of their mathematical nature. We also propose another Integrated Environment (IE) for the design and implementation of safety-critical systems. In this study, a nuclear FED-style design specification and analysis (NuFDS) approach was proposed for PLC based safety-critical systems. The NuFDS approach is suggested in a straightforward manner for the effective and formal specification and analysis of software designs. Accordingly, the proposed NuFDS approach comprises one technique for specifying the software design and another for analyzing the software design. In addition, with the NuFDS approach, we can analyze the safety of software on the basis of fault tree synthesis. To analyze the design phase more effectively, we propose a technique of fault tree synthesis, along with a universal fault tree template for the architecture modules of nuclear software. Various tools have been needed to make software V and V more convenient. We therefore developed four kinds of computer-aided software engineering tools that could be used in accordance with the software's life cycle to

A novel approach for treatment of CO{sub 2} from fossil fired power plants, Part A: The integrated systems ITRPP

Energy Technology Data Exchange (ETDEWEB)

Minutillo, M.; Perna, A. [Department of Industrial Engineering, University of Cassino, Via G. di Biasio, 43, 03043 Cassino, Frosinone (Italy)

2009-05-15

The environmental issues, due to the global warming caused by the rising concentration of greenhouse gases in the atmosphere, require new strategies aimed to increase power plants efficiencies and to reduce CO{sub 2} emissions. This two-paper work focuses on a different approach for capture and reduction of CO{sub 2} from flue gases of fossil fired power plant, with respect to conventional post-combustion technologies. This approach consists of flue gases utilization as co-reactants in a catalytic process, the tri-reforming process, to generate a synthesis gas suitable in chemical and energy industries (methanol, DME, etc.). In fact, the further conversion of syngas to a transportation fuel, such as methanol, is an attractive solution to introduce near zero-emission technologies (i.e. fuel cells) in vehicular applications. In this Part A, integrated systems for co-generation of electrical power and synthesis gas useful for methanol production have been defined and their performance has been investigated considering different flue gases compositions. In Part B, in order to verify the environmental advantages and energy suitability of these systems, their comparison with conventional technology for methanol production is carried out. The integrated systems (ITRPP, Integrated Tri-Reforming Power Plant) consist of a power island, based on a thermal power plant, and a methane tri-reforming island in which the power plants' exhausts react with methane to produce a synthesis gas used for methanol synthesis. As power island, a steam turbine power plant fuelled with coal and a gas turbine combined cycle fuelled with natural gas have been considered. The energy and environmental analysis of ITRPP systems (ITRPP-SC and ITRPP-CC) has been carried out by using thermochemical and thermodynamic models which have allowed to calculate the syngas composition, to define the energy and mass balances and to estimate the CO{sub 2} emissions for each ITRPP configuration. The

Human-Systems Integration Processes

Data.gov (United States)

National Aeronautics and Space Administration — The goal of this project is to baseline a Human-Systems Integration Processes (HSIP) document as a companion to the NASA-STD-3001 and Human Integration Design...

Systems Engineering and Integration for Advanced Life Support System and HST

Science.gov (United States)

Kamarani, Ali K.

2005-01-01

Systems engineering (SE) discipline has revolutionized the way engineers and managers think about solving issues related to design of complex systems: With continued development of state-of-the-art technologies, systems are becoming more complex and therefore, a systematic approach is essential to control and manage their integrated design and development. This complexity is driven from integration issues. In this case, subsystems must interact with one another in order to achieve integration objectives, and also achieve the overall system's required performance. Systems engineering process addresses these issues at multiple levels. It is a technology and management process dedicated to controlling all aspects of system life cycle to assure integration at all levels. The Advanced Integration Matrix (AIM) project serves as the systems engineering and integration function for the Human Support Technology (HST) program. AIM provides means for integrated test facilities and personnel for performance trade studies, analyses, integrated models, test results, and validated requirements of the integration of HST. The goal of AIM is to address systems-level integration issues for exploration missions. It will use an incremental systems integration approach to yield technologies, baselines for further development, and possible breakthrough concepts in the areas of technological and organizational interfaces, total information flow, system wide controls, technical synergism, mission operations protocols and procedures, and human-machine interfaces.

Plasma synthesis of rare earth doped integrated optical waveguides

Energy Technology Data Exchange (ETDEWEB)

Raoux, S.; Anders, S.; Yu, K.M.; Brown, I.G. [Lawrence Berkeley Lab., CA (United States); Ivanov, I.C. [Charles Evans & Associates, Redwood City, CA (United States)

1995-03-01

We describe a novel means for the production of optically active planar waveguides. The makes use of a low energy plasma deposition. Cathodic-arc-produced metal plasmas the metallic components of the films and gases are added to form compound films. Here we discuss the synthesis of Al{sub 2{minus}x}ER{sub x}O{sub 3} thin films. The erbium concentration (x) can vary from 0 to 100% and the thickness of the film can be from Angstroms to microns. In such material, at high active center concentration (x=l% to 20%), erbium ions give rise to room temperature 1.53{mu}m emission which has minimum loss in silica-based optical fibers. With this technique, multilayer integrated planar waveguide structures can be grown, such as Al{sub 2}O{sub 3}/Al{sub 2{minus}x}Er{sub x}O{sub 3}/Al{sub 2}O{sub 3}/Si, for example.

The AutoBayes Program Synthesis System: System Description

Science.gov (United States)

Fischer, Bernd; Pressburger, Thomas; Rosu, Grigore; Schumann, Johann; Norvog, Peter (Technical Monitor)

2001-01-01

AUTOBAYES is a fully automatic program synthesis system for the statistical data analysis domain. Its input is a concise description of a data analysis problem in the form of a statistical model; its output is optimized and fully documented C/C++ code which can be linked dynamically into the Matlab and Octave environments. AUTOBAYES synthesizes code by a schema-guided deductive process. Schemas (i.e., code templates with associated semantic constraints) are applied to the original problem and recursively to emerging subproblems. AUTOBAYES complements this approach by symbolic computation to derive closed-form solutions whenever possible. In this paper, we concentrate on the interaction between the symbolic computations and the deductive synthesis process. A statistical model specifies for each problem variable (i.e., data or parameter) its properties and dependencies in the form of a probability distribution, A typical data analysis task is to estimate the best possible parameter values from the given observations or measurements. The following example models normal-distributed data but takes prior information (e.g., from previous experiments) on the data's mean value and variance into account.

Integrated design for space transportation system

CERN Document Server

Suresh, B N

2015-01-01

The book addresses the overall integrated design aspects of a space transportation system involving several disciplines like propulsion, vehicle structures, aerodynamics, flight mechanics, navigation, guidance and control systems, stage auxiliary systems, thermal systems etc. and discusses the system approach for design, trade off analysis, system life cycle considerations, important aspects in mission management, the risk assessment, etc. There are several books authored to describe the design aspects of various areas, viz., propulsion, aerodynamics, structures, control, etc., but there is no book which presents space transportation system (STS) design in an integrated manner. This book attempts to fill this gap by addressing systems approach for STS design, highlighting the integrated design aspects, interactions between various subsystems and interdependencies. The main focus is towards the complex integrated design to arrive at an optimum, robust and cost effective space transportation system. The orbit...

Adaptive Integration of Nonsmooth Dynamical Systems

Science.gov (United States)

2017-10-11

2017 W911NF-12-R-0012-03: Adaptive Integration of Nonsmooth Dynamical Systems The views, opinions and/or findings contained in this report are those of...Integration of Nonsmooth Dynamical Systems Report Term: 0-Other Email: drum@gwu.edu Distribution Statement: 1-Approved for public release; distribution is...classdrake_1_1systems_1_1_integrator_base.html ; 3) a solver for dynamical systems with arbitrary unilateral and bilateral constraints (the key component of the time stepping systems )- see

Video Texture Synthesis Based on Flow-Like Stylization Painting

Directory of Open Access Journals (Sweden)

Qian Wenhua

2014-01-01

Full Text Available The paper presents an NP-video rendering system based on natural phenomena. It provides a simple nonphotorealistic video synthesis system in which user can obtain a flow-like stylization painting and infinite video scene. Firstly, based on anisotropic Kuwahara filtering in conjunction with line integral convolution, the phenomena video scene can be rendered to flow-like stylization painting. Secondly, the methods of frame division, patches synthesis, will be used to synthesize infinite playing video. According to selection examples from different natural video texture, our system can generate stylized of flow-like and infinite video scenes. The visual discontinuities between neighbor frames are decreased, and we also preserve feature and details of frames. This rendering system is easy and simple to implement.

Designing charge-sensitive preamplifiers based on low-noise analog integrated circuits

International Nuclear Information System (INIS)

Agakhanyan, T.M.

1998-01-01

The methodology for designing charge-sensitive preamplifiers on the low-noise analog integral circuits, including all the stages: the mathematical synthesis with optimization of the intermediate function; the scheme-technical synthesis with parametric optimization of the scheme and analysis of draft projects with the parameter verification is presented. The designing is conducted on the basis of requirements for signal parameters and noise indices of the preamplifier. The system of automated designing of the charge-sensitive preamplifiers on the low-noise analog integral circuits is developed [ru

Deep integration: a paradigm shift in the synthesis of active antenna systems

NARCIS (Netherlands)

Maaskant, R.

2017-01-01

Deep integration is the visionary future trend of merging conducting, semi-conducting and insulating materials into a single heterogeneous structure that is capable of offering multi-functional RF features. This paper introduces the deep integration concept, describes its potential advantages, lists

What Synthesis Methodology Should I Use? A Review and Analysis of Approaches to Research Synthesis

Science.gov (United States)

Schick-Makaroff, Kara; MacDonald, Marjorie; Plummer, Marilyn; Burgess, Judy; Neander, Wendy

2016-01-01

Background When we began this process, we were doctoral students and a faculty member in a research methods course. As students, we were facing a review of the literature for our dissertations. We encountered several different ways of conducting a review but were unable to locate any resources that synthesized all of the various synthesis methodologies. Our purpose is to present a comprehensive overview and assessment of the main approaches to research synthesis. We use ‘research synthesis’ as a broad overarching term to describe various approaches to combining, integrating, and synthesizing research findings. Methods We conducted an integrative review of the literature to explore the historical, contextual, and evolving nature of research synthesis. We searched five databases, reviewed websites of key organizations, hand-searched several journals, and examined relevant texts from the reference lists of the documents we had already obtained. Results We identified four broad categories of research synthesis methodology including conventional, quantitative, qualitative, and emerging syntheses. Each of the broad categories was compared to the others on the following: key characteristics, purpose, method, product, context, underlying assumptions, unit of analysis, strengths and limitations, and when to use each approach. Conclusions The current state of research synthesis reflects significant advancements in emerging synthesis studies that integrate diverse data types and sources. New approaches to research synthesis provide a much broader range of review alternatives available to health and social science students and researchers. PMID:29546155

What Synthesis Methodology Should I Use? A Review and Analysis of Approaches to Research Synthesis.

Directory of Open Access Journals (Sweden)

Kara Schick-Makaroff

2016-03-01

Full Text Available Background: When we began this process, we were doctoral students and a faculty member in a research methods course. As students, we were facing a review of the literature for our dissertations. We encountered several different ways of conducting a review but were unable to locate any resources that synthesized all of the various synthesis methodologies. Our purpose is to present a comprehensive overview and assessment of the main approaches to research synthesis. We use ‘research synthesis’ as a broad overarching term to describe various approaches to combining, integrating, and synthesizing research findings. Methods: We conducted an integrative review of the literature to explore the historical, contextual, and evolving nature of research synthesis. We searched five databases, reviewed websites of key organizations, hand-searched several journals, and examined relevant texts from the reference lists of the documents we had already obtained. Results: We identified four broad categories of research synthesis methodology including conventional, quantitative, qualitative, and emerging syntheses. Each of the broad categories was compared to the others on the following: key characteristics, purpose, method, product, context, underlying assumptions, unit of analysis, strengths and limitations, and when to use each approach. Conclusions: The current state of research synthesis reflects significant advancements in emerging synthesis studies that integrate diverse data types and sources. New approaches to research synthesis provide a much broader range of review alternatives available to health and social science students and researchers.

Integration of deep geothermal energy and woody biomass conversion pathways in urban systems

International Nuclear Information System (INIS)

Moret, Stefano; Peduzzi, Emanuela; Gerber, Léda; Maréchal, François

2016-01-01

Highlights: • Novel optimization-based methodology to integrate renewable energy systems in cities. • Multiperiod model including storage, heat integration and Life Cycle Assessment. • Case study: systematic assessment of deep geothermal and wood conversion pathways. • Identification of novel wood-geothermal hybrid systems leading to higher efficiencies. • Extensive Supplementary Material to ensure full reproducibility of the work. - Abstract: Urban systems account for about two-thirds of global primary energy consumption and energy-related greenhouse gas emissions, with a projected increasing trend. Deep geothermal energy and woody biomass can be used for the production of heat, electricity and biofuels, thus constituting a renewable alternative to fossil fuels for all end-uses in cities: heating, cooling, electricity and mobility. This paper presents a methodology to assess the potential for integrating deep geothermal energy and woody biomass in an urban energy system. The city is modeled in its entirety as a multiperiod optimization problem with the total annual cost as an objective, assessing as well the environmental impact with a Life Cycle Assessment approach. For geothermal energy, deep aquifers and Enhanced Geothermal Systems are considered for stand-alone production of heat and electricity, and for cogeneration. For biomass, besides direct combustion and cogeneration, conversion to biofuels by a set of alternative processes (pyrolysis, Fischer-Tropsch synthesis and synthetic natural gas production) is studied. With a scenario-based approach, all pathways are first individually evaluated. Secondly, all possible combinations between geothermal and biomass options are systematically compared, taking into account the possibility of hybrid systems. Results show that integrating these two resources generates configurations featuring both lower costs and environmental impacts. In particular, synergies are found in innovative hybrid systems using

Evolutionary systems biology: historical and philosophical perspectives on an emerging synthesis.

Science.gov (United States)

O'Malley, Maureen A

2012-01-01

Systems biology (SB) is at least a decade old now and maturing rapidly. A more recent field, evolutionary systems biology (ESB), is in the process of further developing system-level approaches through the expansion of their explanatory and potentially predictive scope. This chapter will outline the varieties of ESB existing today by tracing the diverse roots and fusions that make up this integrative project. My approach is philosophical and historical. As well as examining the recent origins of ESB, I will reflect on its central features and the different clusters of research it comprises. In its broadest interpretation, ESB consists of five overlapping approaches: comparative and correlational ESB; network architecture ESB; network property ESB; population genetics ESB; and finally, standard evolutionary questions answered with SB methods. After outlining each approach with examples, I will examine some strong general claims about ESB, particularly that it can be viewed as the next step toward a fuller modern synthesis of evolutionary biology (EB), and that it is also the way forward for evolutionary and systems medicine. I will conclude with a discussion of whether the emerging field of ESB has the capacity to combine an even broader scope of research aims and efforts than it presently does.

Computational method and system for modeling, analyzing, and optimizing DNA amplification and synthesis

Science.gov (United States)

Vandersall, Jennifer A.; Gardner, Shea N.; Clague, David S.

2010-05-04

A computational method and computer-based system of modeling DNA synthesis for the design and interpretation of PCR amplification, parallel DNA synthesis, and microarray chip analysis. The method and system include modules that address the bioinformatics, kinetics, and thermodynamics of DNA amplification and synthesis. Specifically, the steps of DNA selection, as well as the kinetics and thermodynamics of DNA hybridization and extensions, are addressed, which enable the optimization of the processing and the prediction of the products as a function of DNA sequence, mixing protocol, time, temperature and concentration of species.

Pharmaceutical supply chain models: A synthesis from a systems view of operations research

Directory of Open Access Journals (Sweden)

Ettore Settanni

Full Text Available This research evaluates reconfiguration opportunities in Pharmaceutical Supply Chains (PSC resulting from technology interventions in manufacturing, and new, more patient-centric delivery models. A critical synthesis of the academic and practice literature is used to identify, conceptualise, analyse and categorise PSC models. From a theoretical perspective, a systems view of operations research is adopted to provide insights on a broader range of OR activities, from conceptual to mathematical modelling and model solving, up to implementation.The research demonstrates that: 1 current definitions of the PSC are largely production-centric and fail to capture patient consumption, and hence healthcare outcomes; 2 most PSC mathematical models lack adequate conceptualisation of the structure and behaviour of the supply chain, and the boundary conditions that need to be considered for a given problem; 3 models do not adequately specify current unit operations or future production technology options, and are therefore unable to address the critical questions around alternative product or process technologies; 4 economic evaluations are limited to direct costing, rather than systemic approaches such as supply chain costing and total cost of ownership.While current models of the PSC may help with the optimisation of specific unit operations, their theoretical benefits could be offset by the dynamics of complex upstream (supply and downstream (distribution and healthcare delivery systems. To overcome these limitations, this research provides initial directions towards an integrated systems approach to PSC modelling. This perspective involves problem conceptualisation and boundary definition; design, formulation and solution of mathematical models, through to practical implementation of identified solutions. For both academics and practitioners, research findings suggest a systems approach to PSC modelling can provide improved conceptualisation and

Development of automatic combinatorial system for synthesis of nanoparticles using microreactors

Energy Technology Data Exchange (ETDEWEB)

Watanabe, Kosuke; Maeda, Hideaki [Interdisciplinary Graduate School of Engineering Sciences, Kyushu University, 6-1 Kasuga-koen, Kasuga, Fukuoka, 816-8580 (Japan); Orimoto, Yuuichi; Yamashita, Kenichi; Uehara, Masato; Nakamura, Hiroyuki [Measurement Solution Research Center, National Institute of Advanced Industrial Science and Technology (AIST), 807-1, Shuku, Tosu, Saga, 841-0052 (Japan); Furuya, Takeshi, E-mail: maeda-h@aist.go.jp [Nanosystem Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki, 305-8565 (Japan)

2011-10-29

In this study, automatic system for combinatorial synthesis of nanoparticles (NPs) was developed and optimization of reaction parameter for NPs synthesis was performed. Microreactor was employed for kinetic control constantly. Programmable equipments were employed for additional speed up and used a microreactor. Six reaction condition parameters were systematically combined to produce CdSe synthesis condition sets. Reaction conditions of 3404 experimental sets were synthesized and characterized in 1 month. As a result of some multivariate analyses using the numerous and complicated data, we found as follows: 1) neural network is an effective method to analyze data from combinatorial synthesis, 2) weighting evaluation method was effective to find the condition for balanced NP properties.

ADDRESS SYSTEM INTEGRATION BUSINESS

Directory of Open Access Journals (Sweden)

Lionel Manuel Carbonell-Zamora

2016-01-01

Full Text Available The Integrated Strategic Direction constitutes a superior stage of Direction that expresses the coordinated system of external and internal relations with full participation in order to reach the vision of the organization. It can be insured by the use of the Strategic Direction model for the integration of the Company Direction System. This model has been applied in several companies. Recently, it was applied in the Inspection State Unit of MICONS in Santiago de Cuba through the investigation thesis for master degree developed during 18 months which objective was to validate its effectiveness in a budgeted unit, obtaining positive results when the levels of integration in the direction system increased in their external and internal relations expressed in a 37 % and 15 % respectively, which impacted the increment of the efficiency and effectiveness of all processes of the organization. 

Two new discrete integrable systems

International Nuclear Information System (INIS)

Chen Xiao-Hong; Zhang Hong-Qing

2013-01-01

In this paper, we focus on the construction of new (1+1)-dimensional discrete integrable systems according to a subalgebra of loop algebra à 1 . By designing two new (1+1)-dimensional discrete spectral problems, two new discrete integrable systems are obtained, namely, a 2-field lattice hierarchy and a 3-field lattice hierarchy. When deriving the two new discrete integrable systems, we find the generalized relativistic Toda lattice hierarchy and the generalized modified Toda lattice hierarchy. Moreover, we also obtain the Hamiltonian structures of the two lattice hierarchies by means of the discrete trace identity

Secure integrated circuits and systems

CERN Document Server

Verbauwhede, Ingrid MR

2010-01-01

On any advanced integrated circuit or 'system-on-chip' there is a need for security. In many applications the actual implementation has become the weakest link in security rather than the algorithms or protocols. The purpose of the book is to give the integrated circuits and systems designer an insight into the basics of security and cryptography from the implementation point of view. As a designer of integrated circuits and systems it is important to know both the state-of-the-art attacks as well as the countermeasures. Optimizing for security is different from optimizations for speed, area,

SYNTHESIS OF THE TECHNICAL CONTROL SYSTEMS WITH VARIABLE STRUCTURE

Directory of Open Access Journals (Sweden)

2016-01-01

Full Text Available Change. Also the object as a result of an adverse effect is considered. The formal problem definition of synthesis of hardy management system is considered. Model choice criteria ensemble is set. The rule of choice algorithm implementation on the basis of different reference functions is provided. The conclusion is drawn that in case of preliminary processing of the available prior data it is possible to select reference functions correctly which reflect physical processes more precisely. The mathematical description of a dynamic object on the basis of a differential equation, or its decision is provided. Defini- tion of function of a trend is given. Criteria for selection of model of damage are given. The recommendation of modifica- tion of Demark trends algorithm by means of the sliding Yazvinsky's window and a method of self-organization for in- crease of accuracy of creation of a predictive model of damage is made. It is offered to realize a model choice by means of more complex logical analysis of an observed vector in the appropriate situation. Logic-functional control task definition is given and approach to its decision is formulated. The conclusion about what the task of synthesis management system con- sists of is given. This article describes the method of synthesis of control system with variable structure provides increasing survivability control system in a significant change of the external environment, as well as the object itself from the adverse impacts.

Gallium‐68 DOTATATE Production with Automated PET Radiopharmaceutical Synthesis System: A Three Year Experience

Directory of Open Access Journals (Sweden)

Alireza Aslani

2014-10-01

Full Text Available Objective(s: Gallium‐68 (Ga‐68 is an ideal research and hospital‐based PET radioisotope. Currently, the main form of Ga‐68 radiopharmaceutical that is being synthesised in‐house is Ga‐68 conjugated with DOTA based derivatives. The development of automated synthesis systems has increased the reliability, reproducibility and safety of radiopharmaceutical productions. Here we report on our three year, 500 syntheses experience with an automated system for Ga‐68 DOTATATE. Methods: The automated synthesis system we use is divided into three parts of a servomotor modules, b single use sterile synthesis cassettes and, c a computerized system that runs the modules. An audit trail is produced by the system as a requirement for GMP production. The required reagents and chemicals are made in‐. The Germanium breakthrough is determined on a weekly basis. Production yields for each synthesis are calculated to monitor the performance and efficiency of the synthesis. The quality of the final product is assessed after each synthesis by ITLC‐SG and HPLC methods. Results: A total of 500 Ga‐68 DOTATATE syntheses (>800 patient doses were performed between March 2011 and February 2014. The average generator yield was 81.3±0.2% for 2011, 76.7±0.4% for 2012 and 75.0±0.3% for 2013. Ga‐68 DOTATATE yields for 2011, 2012, and 2013 were 81.8±0.4%, 82.2±0.4% and 87.9±0.4%, respectively. These exceed the manufacturer’s expected value of approximately 70%. Germanium breakthrough averaged 8.6×10‐6% of total activity which is well below the recommended level of 0.001%. The average ITLC‐measured radiochemical purity was above 98.5% and the average HPLC‐measured radiochemical purity was above 99.5%. Although there were some system failures during synthesis, there were only eight occasions where the patient scans needed to be rescheduled. Conclusion: In our experience the automated synthesis system performs reliably with a relatively low incident

Health systems guidance appraisal--a critical interpretive synthesis.

Science.gov (United States)

Ako-Arrey, Denis E; Brouwers, Melissa C; Lavis, John N; Giacomini, Mita K

2016-01-22

Health systems guidance (HSG) are systematically developed statements that assist with decisions about options for addressing health systems challenges, including related changes in health systems arrangements. However, the development, appraisal, and reporting of HSG poses unique conceptual and methodological challenges related to the varied types of evidence that are relevant, the complexity of health systems, and the pre-eminence of contextual factors. To address this gap, we are conducting a program of research that aims to create a tool to support the appraisal of HSG and further enhance HSG development and reporting. The focus of this paper was to conduct a knowledge synthesis of the published and grey literatures to determine quality criteria (concepts) relevant for this process. We applied a critical interpretive synthesis (CIS) approach to knowledge synthesis that enabled an iterative, flexible, and dynamic analysis of diverse bodies of literature in order to generate a candidate list of concepts that will constitute the foundational components of the HSG tool. Using our review questions as compasses, we were able to guide the search strategy to look for papers based on their potential relevance to HSG appraisal, development, and reporting. The search strategy included various electronic databases and sources, subject-specific journals, conference abstracts, research reports, book chapters, unpublished data, dissertations, and policy documents. Screening the papers and data extraction was completed independently and in duplicate, and a narrative approach to data synthesis was executed. We identified 43 papers that met eligibility criteria. No existing review was found on this topic, and no HSG appraisal tool was identified. Over one third of the authors implicitly or explicitly identified the need for a high-quality tool aimed to systematically evaluate HSG and contribute to its development/reporting. We identified 30 concepts that may be relevant to the

INTEGRATIVE AUGMENTATION OF STANDARDIZED MANAGEMENT SYSTEMS

Directory of Open Access Journals (Sweden)

Stanislav Karapetrovic

2008-03-01

Full Text Available The development, features and integrating abilities of different international standards related to management systems are discussed. A group of such standards that augment the performance of quality management systems in organizations is specifically focused on. The concept, characteristics and an illustrative example of one augmenting standard, namely ISO 10001, are addressed. Integration of standardized augmenting systems, both by themselves and within the overall management system, is examined. It is argued that, in research and practice alike, integrative augmentation represents the future of standardized quality and other management systems.

Integrable deformations of Lotka-Volterra systems

International Nuclear Information System (INIS)

Ballesteros, Angel; Blasco, Alfonso; Musso, Fabio

2011-01-01

The Hamiltonian structure of a class of three-dimensional (3D) Lotka-Volterra (LV) equations is revisited from a novel point of view by showing that the quadratic Poisson structure underlying its integrability structure is just a real three-dimensional Poisson-Lie group. As a consequence, the Poisson coalgebra map Δ (2) that is given by the group multiplication provides the keystone for the explicit construction of a new family of 3N-dimensional integrable systems that, under certain constraints, contain N sets of deformed versions of the 3D LV equations. Moreover, by considering the most generic Poisson-Lie structure on this group, a new two-parametric integrable perturbation of the 3D LV system through polynomial and rational perturbation terms is explicitly found. -- Highlights: → A new Poisson-Lie approach to the integrability of Lotka-Volterra system is given. → New integrable deformations of the 3D Lotka-Volterra system are obtained. → Integrable Lotka-Volterra-type equations in 3N dimensions are deduced.

Synthesis of a drug-like focused library of trisubstituted pyrrolidines using integrated flow chemistry and batch methods.

Science.gov (United States)

Baumann, Marcus; Baxendale, Ian R; Kuratli, Christoph; Ley, Steven V; Martin, Rainer E; Schneider, Josef

2011-07-11

A combination of flow and batch chemistries has been successfully applied to the assembly of a series of trisubstituted drug-like pyrrolidines. This study demonstrates the efficient preparation of a focused library of these pharmaceutically important structures using microreactor technologies, as well as classical parallel synthesis techniques, and thus exemplifies the impact of integrating innovative enabling tools within the drug discovery process.

Symplectic topology of integrable Hamiltonian systems

International Nuclear Information System (INIS)

Nguyen Tien Zung.

1993-08-01

We study the topology of integrable Hamiltonian systems, giving the main attention to the affine structure of their orbit spaces. In particular, we develop some aspects of Fomenko's theory about topological classification of integrable non-degenerate systems, and consider some relations between such systems and ''pure'' contact and symplectic geometry. We give a notion of integrable surgery and use it to obtain some interesting symplectic structures. (author). Refs, 10 figs

Integrated control system for electron beam processes

Science.gov (United States)

Koleva, L.; Koleva, E.; Batchkova, I.; Mladenov, G.

2018-03-01

The ISO/IEC 62264 standard is widely used for integration of the business systems of a manufacturer with the corresponding manufacturing control systems based on hierarchical equipment models, functional data and manufacturing operations activity models. In order to achieve the integration of control systems, formal object communication models must be developed, together with manufacturing operations activity models, which coordinate the integration between different levels of control. In this article, the development of integrated control system for electron beam welding process is presented as part of a fully integrated control system of an electron beam plant, including also other additional processes: surface modification, electron beam evaporation, selective melting and electron beam diagnostics.

Synthesis of integrated absorption refrigeration systems involving economic and environmental objectives and quantifying social benefits

International Nuclear Information System (INIS)

Lira-Barragán, Luis Fernando; Ponce-Ortega, José María; Serna-González, Medardo; El-Halwagi, Mahmoud M.

2013-01-01

This paper presents a new methodology for energy integration of systems that require absorption refrigeration. It allows heat exchange among process hot and cold streams and the integration of excess process heat as well as external utilities provided by solar energy, fossil fuels and biofuels. An optimization formulation is developed to address the multiple objectives of simultaneously minimizing the total annualized cost and the greenhouse gas emissions while the social impact is measured by the number of jobs generated by the project in the entire life cycle. The economic function accounts for the tax credit obtained by the reduction of greenhouse gas emissions when cleaner technologies are used. The proposed model also considers the optimal selection of different types of solar collectors and the optimal time-based usage of solar energy, fossil fuel, and biofuel. Two example problems are presented to show the applicability of the proposed methodology. -- Highlights: ► An approach for the thermal integration of refrigeration processes is proposed. ► Different forms of sustainable energies are considered in the optimization process. ► Economic and environmental objectives are considered quantifying the number of jobs. ► The availability for the different forms of energy is taken into account. ► Results show significant advantages obtained with the proposed approach

Integrated systems innovations and applications

CERN Document Server

2015-01-01

This book presents the results of discussions and presentation from the latest ISDT event (2014) which was dedicated to the 94th birthday anniversary of Prof. Lotfi A. Zade, father of Fuzzy logic. The book consists of three main chapters, namely: Chapter 1: Integrated Systems Design Chapter 2: Knowledge, Competence and Business Process Management Chapter 3: Integrated Systems Technologies Each article presents novel and scientific research results with respect to the target goal of improving our common understanding of KT integration.

Integrated Reporting Information System -

Data.gov (United States)

Department of Transportation — The Integrated Reporting Information System (IRIS) is a flexible and scalable web-based system that supports post operational analysis and evaluation of the National...

Intelligent Integrated System Health Management

Science.gov (United States)

Figueroa, Fernando

2012-01-01

Intelligent Integrated System Health Management (ISHM) is the management of data, information, and knowledge (DIaK) with the purposeful objective of determining the health of a system (Management: storage, distribution, sharing, maintenance, processing, reasoning, and presentation). Presentation discusses: (1) ISHM Capability Development. (1a) ISHM Knowledge Model. (1b) Standards for ISHM Implementation. (1c) ISHM Domain Models (ISHM-DM's). (1d) Intelligent Sensors and Components. (2) ISHM in Systems Design, Engineering, and Integration. (3) Intelligent Control for ISHM-Enabled Systems

Integration of a Portfolio-based Approach to Evaluate Aerospace R and D Problem Formulation Into a Parametric Synthesis Tool

Science.gov (United States)

Oza, Amit R.

The focus of this study is to improve R&D effectiveness towards aerospace and defense planning in the early stages of the product development lifecycle. Emphasis is on: correct formulation of a decision problem, with special attention to account for data relationships between the individual design problem and the system capability required to size the aircraft, understanding of the meaning of the acquisition strategy objective and subjective data requirements that are required to arrive at a balanced analysis and/or "correct" mix of technology projects, understanding the meaning of the outputs that can be created from the technology analysis, and methods the researcher can use at effectively support decisions at the acquisition and conceptual design levels through utilization of a research and development portfolio strategy. The primary objectives of this study are to: (1) determine what strategy should be used to initialize conceptual design parametric sizing processes during requirements analysis for the materiel solution analysis stage of the product development lifecycle when utilizing data already constructed in the latter phase when working with a generic database management system synthesis tool integration architecture for aircraft design , and (2) assess how these new data relationships can contribute for innovative decision-making when solving acquisition hardware/technology portfolio problems. As such, an automated composable problem formulation system is developed to consider data interactions for the system architecture that manages acquisition pre-design concept refinement portfolio management, and conceptual design parametric sizing requirements. The research includes a way to: • Formalize the data storage and implement the data relationship structure with a system architecture automated through a database management system. • Allow for composable modeling, in terms of level of hardware abstraction, for the product model, mission model, and

Synthesis of tracers using automated radiochemistry and robotics

International Nuclear Information System (INIS)

Dannals, R.F.

1992-07-01

Synthesis of high specific activity radiotracers labeled with short-lived positron-emitting radionuclides for positron emission tomography (PET) often requires handling large initial quantities of radioactivity. High specific activities are required when preparing tracers for use in PET studies of neuroreceptors. A fully automated approach for tracer synthesis is highly desirable. This proposal involves the development of a system for the Synthesis of Tracers using Automated Radiochemistry and Robotics (STARR) for this purpose. While the long range objective of the proposed research is the development of a totally automated radiochemistry system for the production of major high specific activity 11 C-radiotracers for use in PET, the specific short range objectives are the automation of 11 C-methyl iodide ( 11 CH 3 I) production via an integrated approach using both radiochemistry modular labstations and robotics, and the extension of this automated capability to the production of several radiotracers for PET (initially, 11 C-methionine, 3-N-[ 11 C-methyl]spiperone, and [ 11 C]-carfentanil)

Transforming cities towards sustainable low-carbon energy systems using emergy synthesis for support in decision making

International Nuclear Information System (INIS)

Lugaric, Luka; Krajcar, Slavko

2016-01-01

Recognized as implementation actors of operative measures for transition towards a low carbon economy, cities must establish a development roadmap integrating local resources with local energy development plans. A systematic approach does not exist yet and cities develop their plans individually, which is difficult for small and medium sized cities due to limited development capacities. Conventional city planning approaches do not integrate considerations on energy, economy and environment in transition plans in an easily comparable way, yet making decisions with regards to these parameters is vital to determine outcomes of planned developments on future sustainability of the city. The paper presents a framework model based on emergy synthesis which integrates energy, economic and environmental city systems in the decision making process, examining associated theoretical challenges and application limitations. The method is applied on the city of Sisak in Croatia which has developed plans to implement several initiatives geared towards creating a smart energy city. The model enables simulation and assessment of impacts of individual projects targeting the development of a smart energy city on city sustainability expressed through emergy performance, used as a tool for evaluating local development alternatives within the boundary of local resources. - Highlights: • Key concepts of present city development trends towards sustainability are examined. • Emergy synthesis is examined and applied as a tool for policy and decision makers. • Emergy model of a small city is developed, along with submodels for renewable energy sources and buildings. • Simulation of 5 different projects shows impacts on overall city sustainability in a comparable manner. • Increase in emergy sustainability index is confirmed after presumed implementation of simulated projects.

Synthesis of relay control systems for nuclear reactors

International Nuclear Information System (INIS)

Postnikov, N.S.

1996-01-01

The problem on stabilizing an oscillatory-unstable reactor by a single-link relay system, the characteristics whereof have a dead zone and hysteresis loop, is considered. The methodology of synthesis of feedback law, providing for stochastic steady-state mode of reactor operation with the minimum frequency of control impact introduction is proposed. This methodology is applicable to general-type relay systems with arbitrary oscillatory-unstable objects. 6 refs., 5 figs

The assembly and use of continuous flow systems for chemical synthesis.

Science.gov (United States)

Britton, Joshua; Jamison, Timothy F

2017-11-01

The adoption of and opportunities in continuous flow synthesis ('flow chemistry') have increased significantly over the past several years. Continuous flow systems provide improved reaction safety and accelerated reaction kinetics, and have synthesised several active pharmaceutical ingredients in automated reconfigurable systems. Although continuous flow platforms are commercially available, systems constructed 'in-lab' provide researchers with a flexible, versatile, and cost-effective alternative. Herein, we describe the assembly and use of a modular continuous flow apparatus from readily available and affordable parts in as little as 30 min. Once assembled, the synthesis of a sulfonamide by reacting 4-chlorobenzenesulfonyl chloride with dibenzylamine in a single reactor coil with an in-line quench is presented. This example reaction offers the opportunity to learn several important skills including reactor construction, charging of a back-pressure regulator, assembly of stainless-steel syringes, assembly of a continuous flow system with multiple junctions, and yield determination. From our extensive experience of single-step and multistep continuous flow synthesis, we also describe solutions to commonly encountered technical problems such as precipitation of solids ('clogging') and reactor failure. Following this protocol, a nonspecialist can assemble a continuous flow system from reactor coils, syringes, pumps, in-line liquid-liquid separators, drying columns, back-pressure regulators, static mixers, and packed-bed reactors.

Data Entities and Information System Matrix for Integrated Agriculture Information System (IAIS)

Science.gov (United States)

Budi Santoso, Halim; Delima, Rosa

2018-03-01

Integrated Agriculture Information System is a system that is developed to process data, information, and knowledge in Agriculture sector. Integrated Agriculture Information System brings valuable information for farmers: (1) Fertilizer price; (2) Agriculture technique and practise; (3) Pest management; (4) Cultivation; (5) Irrigation; (6) Post harvest processing; (7) Innovation in agriculture processing. Integrated Agriculture Information System contains 9 subsystems. To bring an integrated information to the user and stakeholder, it needs an integrated database approach. Thus, researchers describes data entity and its matrix relate to subsystem in Integrated Agriculture Information System (IAIS). As a result, there are 47 data entities as entities in single and integrated database.

Integrated Project Management System description

International Nuclear Information System (INIS)

1987-03-01

The Uranium Mill Tailings Remedial Action (UMTRA) Project is a Department of Energy (DOE) designated Major System Acquisition (MSA). To execute and manage the Project mission successfully and to comply with the MSA requirements, the UMTRA Project Office (''Project Office'') has implemented and operates an Integrated Project Management System (IPMS). The Project Office is assisted by the Technical Assistance Contractor's (TAC) Project Integration and Control (PIC) Group in system operation. Each participant, in turn, provides critical input to system operation and reporting requirements. The IPMS provides a uniform structured approach for integrating the work of Project participants. It serves as a tool for planning and control, workload management, performance measurement, and specialized reporting within a standardized format. This system description presents the guidance for its operation. Appendices 1 and 2 contain definitions of commonly used terms and abbreviations and acronyms, respectively. 17 figs., 5 tabs

RISK MITIGATION IN THE BANKING SYSTEM IN THE CONTEXT OF INTEGRATION IN THE EUROPEAN UNION

Directory of Open Access Journals (Sweden)

Laura – Maria POPESCU

2013-06-01

Full Text Available The article aims to highlight the measures adopted in the financial-banking system in the context of the European integration, according to risk analysis perspectives. The first part provides details on the vulnerability sources in terms of banking risks and their approach from various perspectives. Subsequently, based on the identified risks, a series of measures are proposed to limit them within the banking system. In terms of the work hypotheses, they are confirmed, thus increasing the harmonization level of theories throughout the European Union. Research was based on methods such as analysis, synthesis and induction, used to select the opinion of specialists in the field on the studied matter, and deduction, through the cross-section method, thus following the evolution and measures adopted in time. Following the analysis, a need was noticed for the implementation of an efficient banking risk management system, together with drafting additional regulations, so that the banking system is better prepared to handle new challenges generated by the crisis. The term afferent to the accession and integration in the European Union implied a stage requiring a radical change of the Romanian banking system, considering issues such as Romania’s economic development, leading to an increase of the banking mediation process.

Bourbaki's structure theory in the problem of complex systems simulation models synthesis and model-oriented programming

Science.gov (United States)

Brodsky, Yu. I.

2015-01-01

The work is devoted to the application of Bourbaki's structure theory to substantiate the synthesis of simulation models of complex multicomponent systems, where every component may be a complex system itself. An application of the Bourbaki's structure theory offers a new approach to the design and computer implementation of simulation models of complex multicomponent systems—model synthesis and model-oriented programming. It differs from the traditional object-oriented approach. The central concept of this new approach and at the same time, the basic building block for the construction of more complex structures is the concept of models-components. A model-component endowed with a more complicated structure than, for example, the object in the object-oriented analysis. This structure provides to the model-component an independent behavior-the ability of standard responds to standard requests of its internal and external environment. At the same time, the computer implementation of model-component's behavior is invariant under the integration of models-components into complexes. This fact allows one firstly to construct fractal models of any complexity, and secondly to implement a computational process of such constructions uniformly-by a single universal program. In addition, the proposed paradigm allows one to exclude imperative programming and to generate computer code with a high degree of parallelism.

Nuclear plants gain integrated information systems

International Nuclear Information System (INIS)

Villavicencio-Ramirez, A.; Rodriquez-Alvarez, J.M.

1994-01-01

With the objective of simplifying the complex mesh of computing devices employed within nuclear power plants, modern technology and integration techniques are being used to form centralized (but backed up) databases and distributed processing and display networks. Benefits are immediate as a result of the integration and the use of standards. The use of a unique data acquisition and database subsystem optimizes the high costs of engineering, as this task is done only once for the life span of the system. This also contributes towards a uniform user interface and allows for graceful expansion and maintenance. This article features an integrated information system, Sistema Integral de Informacion de Proceso (SIIP). The development of this system enabled the Laguna Verde Nuclear Power plant to fully use the already existing universe of signals and its related engineering during all plant conditions, namely, start up, normal operation, transient analysis, and emergency operation. Integrated systems offer many advantages over segregated systems, and this experience should benefit similar development efforts in other electric power utilities, not only for nuclear but also for other types of generating plants

Smart power systems and renewable energy system integration

CERN Document Server

2016-01-01

This monograph presents a wider spectrum of researches, developments, and case specific studies in the area of smart power systems and integration of renewable energy systems. The book will be for the benefit of a wider audience including researchers, postgraduate students, practicing engineers, academics, and regulatory policy makers. It covers a wide range of topics from fundamentals, and modelling and simulation aspects of traditional and smart power systems to grid integration of renewables; Micro Grids; challenges in planning and operation of a smart power system; risks, security, and stability in smart operation of a power system; and applied research in energy storage. .

NASA UAS Integration into the NAS Project: Human Systems Integration

Science.gov (United States)

Shively, Jay

2016-01-01

This presentation provides an overview of the work the Human Systems Integration (HSI) sub-project has done on detect and avoid (DAA) displays while working on the UAS (Unmanned Aircraft System) Integration into the NAS project. The most recent simulation on DAA interoperability with Traffic Collision Avoidance System (TCAS) is discussed in the most detail. The relationship of the work to the larger UAS community and next steps are also detailed.

The integration of renewable energy in the French electricity system: what challenges for optimization?

International Nuclear Information System (INIS)

Mathieu, Mathilde; Ruedinger, Andreas; Pescia, Dimitri

2016-01-01

Based on research reports and dialogue through expert seminars organized by IDDRI and Agora Energiewende in 2015, this Working Paper proposes a synthesis of the main challenges for the integration of renewable energies using an analysis of the electricity system and its potential for optimization over different time frames: the potential evolution of electricity systems at the regional and national levels in France between now and 2030; an analysis of the needs and options for flexibility services beyond production systems; the potential for optimization of instruments to encourage short-term integration in line with changes in regulation regarding RES support schemes. Achieving the targets for renewable energy development (RES-E) in France (40% share of the electricity consumption) and in Europe (approximately 50%) by 2030 poses new integration challenges. The successful transformation of the electricity system based on a significant renewable component requires a systemic approach which takes into account: the evolution of demand and supply (for electricity and all energy), the interactions and competition between flexibility options for system stabilization (interconnections, active demand-side management, storage), the development of relevant infrastructure and articulation between the technical system and market design. A forward-looking analysis of electricity systems helps to assess this increase in flexibility requirements while identifying several optimization options to facilitate RES integration, starting with regional coordination. France already has a flexible electricity system, thanks notably to its hydro potential. Even so, its evolution towards 40% RES by 2030 calls for some strategic choices. On the one hand, drawing up a long-term trajectory for the evolution of electricity demand - in terms of volume as well as the nature of needs addressed - seems essential to bring coherence to the evolution of the technology portfolio and to increase the

Synthesis and structure of two-dimensional transition-metal dichalcogenides

KAUST Repository

Shi, Yumeng; Zhang, Hua; Chang, Wen-Hao; Shin, Hyeon Suk; Li, Lain-Jong

2015-01-01

Two-dimensional (2D) transition-metal dichalcogenides (TMDCs) exhibit unique electrical, optical, thermal, and mechanical properties, which enable them to be used as building blocks in compact and lightweight integrated electronic systems. The controllable and reliable synthesis of atomically thin TMDCs is essential for their practical application. Recent progress in large-area synthesis of monolayer TMDCs paves the way for practical production of various 2D TMDC layers. The intrinsic optical and electrical properties of monolayer TMDCs can be defined by stoichiometry during synthesis. By manipulating the lattice structure or layer stacking manner, it is possible to create atomically thin van der Waals materials with unique and unexplored physical properties. In this article, we review recent developments in the synthesis of TMDC monolayers, alloys, and heterostructures, which shine light on the design of novel TMDCs with desired functional properties.

Synthesis and structure of two-dimensional transition-metal dichalcogenides

KAUST Repository

Shi, Yumeng

2015-07-13

Two-dimensional (2D) transition-metal dichalcogenides (TMDCs) exhibit unique electrical, optical, thermal, and mechanical properties, which enable them to be used as building blocks in compact and lightweight integrated electronic systems. The controllable and reliable synthesis of atomically thin TMDCs is essential for their practical application. Recent progress in large-area synthesis of monolayer TMDCs paves the way for practical production of various 2D TMDC layers. The intrinsic optical and electrical properties of monolayer TMDCs can be defined by stoichiometry during synthesis. By manipulating the lattice structure or layer stacking manner, it is possible to create atomically thin van der Waals materials with unique and unexplored physical properties. In this article, we review recent developments in the synthesis of TMDC monolayers, alloys, and heterostructures, which shine light on the design of novel TMDCs with desired functional properties.

Common Systems Integration Lab (CSIL)

Data.gov (United States)

Federal Laboratory Consortium — The Common Systems Integration Lab (CSIL)supports the PMA-209 Air Combat Electronics Program Office. CSIL also supports development, test, integration and life cycle...

Integrated Systems Health Management for Intelligent Systems

Science.gov (United States)

Figueroa, Fernando; Melcher, Kevin

2011-01-01

The implementation of an integrated system health management (ISHM) capability is fundamentally linked to the management of data, information, and knowledge (DIaK) with the purposeful objective of determining the health of a system. It is akin to having a team of experts who are all individually and collectively observing and analyzing a complex system, and communicating effectively with each other in order to arrive at an accurate and reliable assessment of its health. In this paper, concepts, procedures, and approaches are presented as a foundation for implementing an intelligent systems ]relevant ISHM capability. The capability stresses integration of DIaK from all elements of a system. Both ground-based (remote) and on-board ISHM capabilities are compared and contrasted. The information presented is the result of many years of research, development, and maturation of technologies, and of prototype implementations in operational systems.

A 2+1 non-isospectral discrete integrable system and its discrete integrable coupling system

International Nuclear Information System (INIS)

Yu Fajun; Zhang Hongqing

2006-01-01

In this Letter by considering a (2+1)-dimensional discrete non-isospectral linear problem, a new (2+1)-dimensional integrable lattice hierarchy is constructed. It shows that generalization of the Blaszak-Marciniak lattice hierarchy can be obtained as a reduction. Then an extended algebraic system X-bar of X is presented, from which the integrable coupling system of the (2+1)-dimensional discrete non-isospectral Blaszak-Marciniak lattice equations are obtained

Integrated Monitoring System of Production Processes

Directory of Open Access Journals (Sweden)

Oborski Przemysław

2016-12-01

Full Text Available Integrated monitoring system for discrete manufacturing processes is presented in the paper. The multilayer hardware and software reference model was developed. Original research are an answer for industry needs of the integration of information flow in production process. Reference model corresponds with proposed data model based on multilayer data tree allowing to describe orders, products, processes and save monitoring data. Elaborated models were implemented in the integrated monitoring system demonstrator developed in the project. It was built on the base of multiagent technology to assure high flexibility and openness on applying intelligent algorithms for data processing. Currently on the base of achieved experience an application integrated monitoring system for real production system is developed. In the article the main problems of monitoring integration are presented, including specificity of discrete production, data processing and future application of Cyber-Physical-Systems. Development of manufacturing systems is based more and more on taking an advantage of applying intelligent solutions into machine and production process control and monitoring. Connection of technical systems, machine tools and manufacturing processes monitoring with advanced information processing seems to be one of the most important areas of near future development. It will play important role in efficient operation and competitiveness of the whole production system. It is also important area of applying in the future Cyber-Physical-Systems that can radically improve functionally of monitoring systems and reduce the cost of its implementation.

Decomposition with thermoeconomic isolation applied to the optimal synthesis/design and operation of an advanced tactical aircraft system

International Nuclear Information System (INIS)

Rancruel, Diego F.; Spakovsky, Michael R. von

2006-01-01

A decomposition methodology based on the concept of 'thermoeconomic isolation' and applied to the synthesis/design and operational optimization of an advanced tactical fighter aircraft is the focus of this paper. The total system is composed of six sub-systems of which five participate with degrees of freedom (493) in the optimization. They are the propulsion sub-system (PS), the environmental control sub-system (ECS), the fuel loop subsystem (FLS), the vapor compression and Polyalphaolefin (PAO) loops sub-system (VC/PAOS), and the airframe sub-system (AFS). The sixth subsystem comprises the expendable and permanent payloads as well as the equipment group. For each of the first five, detailed thermodynamic, geometric, physical, and aerodynamic models at both design and off-design were formulated and implemented. The most promising set of aircraft sub-system and system configurations were then determined based on both an energy integration and aerodynamic performance analysis at each stage of the mission (including the transient ones). Conceptual, time, and physical decomposition were subsequently applied to the synthesis/design and operational optimization of these aircraft configurations as well as to the highly dynamic process of heat generation and dissipation internal to the subsystems. The physical decomposition strategy used (i.e. Iterative Local-Global Optimization-ILGO) is the first to successfully closely approach the theoretical condition of 'thermoeconomic isolation' when applied to highly complex, highly dynamic non-linear systems. Developed at our Center for Energy Systems research, it has been effectively applied to a number of complex stationary and transportation applications

Decomposition with thermoeconomic isolation applied to the optimal synthesis/design and operation of an advanced tactical aircraft system

Energy Technology Data Exchange (ETDEWEB)

Rancruel, Diego F. [Center for Energy Systems Research, Department of Mechanical Engineering, Virginia Polytechnic Institute and State University, Blacksburg, VA 24060 (United States); Spakovsky, Michael R. von [Center for Energy Systems Research, Department of Mechanical Engineering, Virginia Polytechnic Institute and State University, Blacksburg, VA 24060 (United States)]. E-mail: vonspako@vt.edu

2006-12-15

A decomposition methodology based on the concept of 'thermoeconomic isolation' and applied to the synthesis/design and operational optimization of an advanced tactical fighter aircraft is the focus of this paper. The total system is composed of six sub-systems of which five participate with degrees of freedom (493) in the optimization. They are the propulsion sub-system (PS), the environmental control sub-system (ECS), the fuel loop subsystem (FLS), the vapor compression and Polyalphaolefin (PAO) loops sub-system (VC/PAOS), and the airframe sub-system (AFS). The sixth subsystem comprises the expendable and permanent payloads as well as the equipment group. For each of the first five, detailed thermodynamic, geometric, physical, and aerodynamic models at both design and off-design were formulated and implemented. The most promising set of aircraft sub-system and system configurations were then determined based on both an energy integration and aerodynamic performance analysis at each stage of the mission (including the transient ones). Conceptual, time, and physical decomposition were subsequently applied to the synthesis/design and operational optimization of these aircraft configurations as well as to the highly dynamic process of heat generation and dissipation internal to the subsystems. The physical decomposition strategy used (i.e. Iterative Local-Global Optimization-ILGO) is the first to successfully closely approach the theoretical condition of 'thermoeconomic isolation' when applied to highly complex, highly dynamic non-linear systems. Developed at our Center for Energy Systems research, it has been effectively applied to a number of complex stationary and transportation applications.

An automated system for the synthesis of L-6-[18F]fluorodopa

International Nuclear Information System (INIS)

Ruth, T.; Adam, M.; Jivan, S.; Morris, D.; Tyldesley, S.

1990-01-01

The PET chemistry group at TRIUMF has completely automated the synthesis of L-6-[ 18 F]fluorodopa. This was done to reduce the exposure of lab technicians to radioactive and corrosive chemicals used in the process. It also improves reliability and reproducibility of the synthesis. The automation is controlled by an IBM Personal Computer AT running the MS-DOS Operating System. The software for the synthesis was written using the Microsoft QuickBASIC Compiler. Graphic display features were created using the Connell Scientific Graphics EGA Toolkit

DKIST facility management system integration

Science.gov (United States)

White, Charles R.; Phelps, LeEllen

2016-07-01

The Daniel K. Inouye Solar Telescope (DKIST) Observatory is under construction at Haleakalā, Maui, Hawai'i. When complete, the DKIST will be the largest solar telescope in the world. The Facility Management System (FMS) is a subsystem of the high-level Facility Control System (FCS) and directly controls the Facility Thermal System (FTS). The FMS receives operational mode information from the FCS while making process data available to the FCS and includes hardware and software to integrate and control all aspects of the FTS including the Carousel Cooling System, the Telescope Chamber Environmental Control Systems, and the Temperature Monitoring System. In addition it will integrate the Power Energy Management System and several service systems such as heating, ventilation, and air conditioning (HVAC), the Domestic Water Distribution System, and the Vacuum System. All of these subsystems must operate in coordination to provide the best possible observing conditions and overall building management. Further, the FMS must actively react to varying weather conditions and observational requirements. The physical impact of the facility must not interfere with neighboring installations while operating in a very environmentally and culturally sensitive area. The FMS system will be comprised of five Programmable Automation Controllers (PACs). We present a pre-build overview of the functional plan to integrate all of the FMS subsystems.

Development and optimisation of synthesis, characterisation and physical properties of solid materials for strip conductors; purpose oriented synthesis of novel systems. Final report

International Nuclear Information System (INIS)

Guenther, W.; Schoellhorn, R.

1995-06-01

The project reported is part of studies into the performance of HTSC, and was responsible for the following essential tasks: synthesis, characterisation, and optimisation of oxocuprates of the type (RE)Ba 2 Cu 3 O 7 , examination of the relevant corrosion processes and reactivity of the phases, and synthesis of novel systems guided by special model concepts, applying kinetics-controlled low-temperature synthesis. (orig./MM) [de

Explicit integration of some integrable systems of classical mechanics

OpenAIRE

Basak Gancheva, Inna

2011-01-01

The main objective of the thesis is the analytical and geometrical study of several integrable finite-dimentional dynamical systems of classical mechanics, which are closely related, namely: - the classical generalization of the Euler top: the Zhukovski-Volterra (ZV) system describing the free motion of a gyrostat, i.e., a rigid body carrying a symmetric rotator whose axis is fixed in the body; - the Steklov-Lyapunov integrable case of the Kirchhoff equations describing the motio...

Integrated Visualisation and Description of Complex Systems

National Research Council Canada - National Science Library

Goodburn, D

1999-01-01

... on system topographies and feature overlays. System information from the domain's information space is filtered and integrated into a Composite Systems Model that provides a basis for consistency and integration between all system views...

A synthesis theory for self-oscillating adaptive systems /SOAS/

Science.gov (United States)

Horowitz, I.; Smay, J.; Shapiro, A.

1974-01-01

A quantitative synthesis theory is presented for the Self-Oscillating Adaptive System (SOAS), whose nonlinear element has a static, odd character with hard saturation. The synthesis theory is based upon the quasilinear properties of the SOAS to forced inputs, which permits the extension of quantitative linear feedback theory to the SOAS. A reasonable definition of optimum design is shown to be the minimization of the limit cycle frequency. The great advantages of the SOAS is its zero sensitivity to pure gain changes. However, quasilinearity and control of the limit cycle amplitude at the system output, impose additional constraints which partially or completely cancel this advantage, depending on the numerical values of the design parameters. By means of narrow-band filtering, an additional factor is introduced which permits trade-off between filter complexity and limit cycle frequency minimization.

Continuous flow synthesis of nanoparticles using ceramic microfluidic devices

Energy Technology Data Exchange (ETDEWEB)

Gomez-de Pedro, S; Puyol, M; Alonso-Chamarro, J, E-mail: julian.alonso@uab.es [Grup de Sensors i Biosensors, Departament de Quimica, Facultat de Ciencies, Edifici Cn, Universitat Autonoma de Barcelona, Bellaterra 08193 (Spain)

2010-10-15

A microfluidic system based on the low-temperature co-fired ceramics technology (LTCC) is proposed to reproducibly carry out a simple one-phase synthesis and functionalization of monodispersed gold nanoparticles. It takes advantage of the LTCC technology, offering a fast prototyping without the need to use sophisticated facilities, reducing significantly the cost and production time of microfluidic systems. Some other interesting advantages of the ceramic materials compared to glass, silicon or polymers are their versatility and chemical resistivity. The technology enables the construction of multilayered systems, which can integrate other mechanical, electronic and fluidic components in a single substrate. This approach allows rapid, easy, low cost and automated synthesis of the gold colloidal, thus it becomes a useful approach in the progression from laboratory scale to pilot-line scale processes, which is currently demanded.

A Continuous-Exchange Cell-Free Protein Synthesis System Based on Extracts from Cultured Insect Cells

Science.gov (United States)

Stech, Marlitt; Quast, Robert B.; Sachse, Rita; Schulze, Corina; Wüstenhagen, Doreen A.; Kubick, Stefan

2014-01-01

In this study, we present a novel technique for the synthesis of complex prokaryotic and eukaryotic proteins by using a continuous-exchange cell-free (CECF) protein synthesis system based on extracts from cultured insect cells. Our approach consists of two basic elements: First, protein synthesis is performed in insect cell lysates which harbor endogenous microsomal vesicles, enabling a translocation of de novo synthesized target proteins into the lumen of the insect vesicles or, in the case of membrane proteins, their embedding into a natural membrane scaffold. Second, cell-free reactions are performed in a two chamber dialysis device for 48 h. The combination of the eukaryotic cell-free translation system based on insect cell extracts and the CECF translation system results in significantly prolonged reaction life times and increased protein yields compared to conventional batch reactions. In this context, we demonstrate the synthesis of various representative model proteins, among them cytosolic proteins, pharmacological relevant membrane proteins and glycosylated proteins in an endotoxin-free environment. Furthermore, the cell-free system used in this study is well-suited for the synthesis of biologically active tissue-type-plasminogen activator, a complex eukaryotic protein harboring multiple disulfide bonds. PMID:24804975

Transportation and socioeconomic impacts of bypasses on communities : an integrated synthesis of panel data, multilevel, and spatial econometric models with case studies.

Science.gov (United States)

2011-09-21

Title: Transportation and Socioeconomic Impacts of Bypasses on Communities: An Integrated Synthesis of Panel Data, Multilevel, and Spatial Econometric Models with Case Studies. The title used at the start of this project was Transportation and Soc...

Jacobi fields of completely integrable Hamiltonian systems

International Nuclear Information System (INIS)

Giachetta, G.; Mangiarotti, L.; Sardanashvily, G.

2003-01-01

We show that Jacobi fields of a completely integrable Hamiltonian system of m degrees of freedom make up an extended completely integrable system of 2m degrees of freedom, where m additional first integrals characterize a relative motion

Discrete systems and integrability

CERN Document Server

Hietarinta, J; Nijhoff, F W

2016-01-01

This first introductory text to discrete integrable systems introduces key notions of integrability from the vantage point of discrete systems, also making connections with the continuous theory where relevant. While treating the material at an elementary level, the book also highlights many recent developments. Topics include: Darboux and Bäcklund transformations; difference equations and special functions; multidimensional consistency of integrable lattice equations; associated linear problems (Lax pairs); connections with Padé approximants and convergence algorithms; singularities and geometry; Hirota's bilinear formalism for lattices; intriguing properties of discrete Painlevé equations; and the novel theory of Lagrangian multiforms. The book builds the material in an organic way, emphasizing interconnections between the various approaches, while the exposition is mostly done through explicit computations on key examples. Written by respected experts in the field, the numerous exercises and the thoroug...

Applications of cell-free protein synthesis in synthetic biology: Interfacing bio-machinery with synthetic environments.

Science.gov (United States)

Lee, Kyung-Ho; Kim, Dong-Myung

2013-11-01

Synthetic biology is built on the synthesis, engineering, and assembly of biological parts. Proteins are the first components considered for the construction of systems with designed biological functions because proteins carry out most of the biological functions and chemical reactions inside cells. Protein synthesis is considered to comprise the most basic levels of the hierarchical structure of synthetic biology. Cell-free protein synthesis has emerged as a powerful technology that can potentially transform the concept of bioprocesses. With the ability to harness the synthetic power of biology without many of the constraints of cell-based systems, cell-free protein synthesis enables the rapid creation of protein molecules from diverse sources of genetic information. Cell-free protein synthesis is virtually free from the intrinsic constraints of cell-based methods and offers greater flexibility in system design and manipulability of biological synthetic machinery. Among its potential applications, cell-free protein synthesis can be combined with various man-made devices for rapid functional analysis of genomic sequences. This review covers recent efforts to integrate cell-free protein synthesis with various reaction devices and analytical platforms. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Integrated nanoparticle-biomolecule systems for biosensing and bioelectronics.

Science.gov (United States)

Willner, Itamar; Baron, Ronan; Willner, Bilha

2007-04-15

The similar dimensions of biomolecules such as enzymes, antibodies or DNA, and metallic or semiconductor nanoparticles (NPs) enable the synthesis of biomolecule-NP hybrid systems where the unique electronic, photonic and catalytic properties of NPs are combined with the specific recognition and biocatalytic properties of biomolecules. The unique functions of biomolecule-NP hybrid systems are discussed with several examples: (i) the electrical contacting of redox enzymes with electrodes is the basis for the development of enzymatic electrodes for amperometric biosensors or biofuel cell elements. The reconstitution of the apo-glucose oxidase or apo-glucose dehydrogenase on flavin adenine dinucleotide (FAD)-functionalized Au NPs (1.4 nm) associated with electrodes, or on pyrroloquinoline quinone (PQQ)-functionalized Au NPs (1.4 nm) associated with electrodes, respectively, yields electrically contacted enzyme electrodes. The aligned, reconstituted enzymes on the electrode surfaces reveal effective electrical contacting, and the glucose oxidase and glucose dehydrogenase reveal turnover rates of 5000 and 11,800 s(-1), respectively. (ii) The photoexcitation of semiconductor nanoparticles yields fluorescence with a wavelength controlled by the size of the NPs. The fluorescence functions of semiconductor NPs are used to develop a fluorescence resonance energy transfer (FRET) assay for nucleic acids, and specifically, for analyzing telomerase activity in cancer cells. CdSe-ZnS NPs are functionalized by a primer recognized by telomerase, and this is elongated by telomerase extracted from HeLa cancer cells in the presence of dNTPs and Texas-red-functionalized dUTP. The dye integrated into the telomers allows the FRET process that is intensified as telomerization proceeds. Also, the photoexcited electron-hole pair generated in semiconductor NPs is used to generate photocurrents in a CdS-DNA hybrid system associated with an electrode. A redox-active intercalator, methylene blue

Completely integrable 2D Lagrangian systems and related integrable geodesic flows on various manifolds

International Nuclear Information System (INIS)

Yehia, Hamad M

2013-01-01

In this study we have formulated a theorem that generates deformations of the natural integrable conservative systems in the plane into integrable systems on Riemannian and other manifolds by introducing additional parameters into their structures. The relation of explicit solutions of the new and the original dynamics to the corresponding Jacobi (Maupertuis) geodesic flow is clarified. For illustration, we apply the result to three concrete examples of the many available integrable systems in the literature. Complementary integrals in those systems are polynomial in velocity with degrees 3, 4 and 6, respectively. As a special case of the first deformed system, a new several-parameter family of integrable mechanical systems (and geodesic flows) on S 2 is constructed. (paper)

Controller Synthesis for Periodically Forced Chaotic Systems

Science.gov (United States)

Basso, Michele; Genesio, Roberto; Giovanardi, Lorenzo

Delayed feedback controllers are an appealing tool for stabilization of periodic orbits in chaotic systems. Despite their conceptual simplicity, specific and reliable design procedures are difficult to obtain, partly also because of their inherent infinite-dimensional structure. This chapter considers the use of finite dimensional linear time invariant controllers for stabilization of periodic solutions in a general class of sinusoidally forced nonlinear systems. For such controllers — which can be interpreted as rational approximations of the delayed ones — we provide a computationally attractive synthesis technique based on Linear Matrix Inequalities (LMIs), by mixing results concerning absolute stability of nonlinear systems and robustness of uncertain linear systems. The resulting controllers prove to be effective for chaos suppression in electronic circuits and systems, as shown by two different application examples.

Optimal Set-Point Synthesis in HVAC Systems

DEFF Research Database (Denmark)

Komareji, Mohammad; Stoustrup, Jakob; Rasmussen, Henrik

2007-01-01

This paper presents optimal set-point synthesis for a heating, ventilating, and air-conditioning (HVAC) system. This HVAC system is made of two heat exchangers: an air-to-air heat exchanger and a water-to-air heat exchanger. The objective function is composed of the electrical power for different...... components, encompassing fans, primary/secondary pump, tertiary pump, and air-to-air heat exchanger wheel; and a fraction of thermal power used by the HVAC system. The goals that have to be achieved by the HVAC system appear as constraints in the optimization problem. To solve the optimization problem......, a steady state model of the HVAC system is derived while different supplying hydronic circuits are studied for the water-to-air heat exchanger. Finally, the optimal set-points and the optimal supplying hydronic circuit are resulted....

Integrability of some generalized Lotka - Volterra systems

Energy Technology Data Exchange (ETDEWEB)

Bountis, T.C.; Bier, M.; Hijmans, J.

1983-08-08

Several integrable systems of nonlinear ordinary differential equations of the Lotka-Volterra type are identified by the Painleve property and completely integrated. One such integrable case of N first order ode's is found, with N - 2 free parameters and N arbitrary. The concept of integrability of a general dynamical system, not necessarily derived from a hamiltonian, is also discussed.

Multiloop integral system test (MIST)

International Nuclear Information System (INIS)

Gloudemans, J.R.

1989-07-01

The multiloop integral system test (MIST) was part of a multiphase program started in 1983 to address small-break loss-of-coolant accidents (SBLOCAs) specific to Babcock and Wilcox-designed plants. MIST was sponsored by the US Nuclear Regulatory Commission, the Babcock and Wilcox Owners Group, the Electric Power Research Institute, and Babcock and Wilcox. The unique features of the Babcock and Wilcox design, specifically the hot leg U-bends and steam generators, prevented the use of existing integral system data or existing integral system facilities to address the thermal-hydraulic SBLOCA questions. MIST and two other supporting facilities were specifically designed and constructed for this program, and an existing facility -- the once-through integral system (OTIS) -- was also used. Data from MIST and the other facilities will be used to benchmark the adequacy of system codes, such as RELAP5 and TRAC, for predicting abnormal plant transients. The individual tests are described in detail in Volumes 2 through 8 and Volume 11, and are summarized in Volume 1. Inter-group comparisons are addressed in this document, Volume 9. These comparisons are grouped as follows: mapping versus SBLOCA transients, SBLOCA, pump effects, and the effects of noncondensible gases. Appendix A provides an index and description of the microfiched plots for each test, which are enclosed with the corresponding Volumes 2 through 8. 147 figs., 5 tabs

ITER lower port systems integration

Energy Technology Data Exchange (ETDEWEB)

Levesy, B., E-mail: bruno.levesy@iter.org [ITER Organization, CS 90 046, 13067 St Paul Lez Durance Cedex (France); Baker, D.; Boussier, B.; Bryan, S.; Cordier, J.J.; Dremel, M.; Dell' Orco, G.; Daly, E.; Doshi, B.; Jeannoutot, T.; Friconneau, J.P.; Gliss, C.; Le Barbier, R.; Lachevre, F.; Loughlin, M.; Martin, A.; Martins, J.P.; Maruyama, S.; Palmer, J.; Reichle, R. [ITER Organization, CS 90 046, 13067 St Paul Lez Durance Cedex (France)

2011-10-15

The lower port systems are installed inside the vacuum vessel lower ports and in the adjacent port cells. The vacuum vessel ports and penetrations are allocated as follow: -4 ports dedicated to remote handling of the divertor cassettes, contain diagnostics racks and divertor cooling pipes. -5 ports connecting the main vessel to the torus cryopumps, contain divertor cooling pipes, pellet and gas injection pipes and vertical stabilization coil feeders. -3 penetrations connecting torus cryopumps are connected to the vacuum vessel by branch pipes. -Specific penetrations for divertor cooling lines, in-vessel viewing and glow discharge systems. The general layout of the port systems has been revised recently to improve the cryopump (8 t weight, 1.8 m diameter and 2.5 m long) maintenance scheme with remote handling tools and integrate the in-vessel vertical stabilization coil feeders. The port allocation, the pumping ports design, and interfaces in-between ports and cryostat and in-between cryopumps and cryostat have been up-dated. The integration inside the 18 port cells (11 m x 4 m each) has been reviewed to avoid clashes in between systems and to fix the openings in the port cell concrete walls. The new layout integrates safety and neutron-shielding requirements as well as remote handling and maintenance compatibility for the different systems. The paper presents the up-dated integration of the lower port systems inside the ports and the port cells. Interfaces of the port systems with the vacuum vessel, the cryostat and the port cells are described.

DSP Based System for Real time Voice Synthesis Applications Development

OpenAIRE

Arsinte, Radu; Ferencz, Attila; Miron, Costin

2008-01-01

This paper describes an experimental system designed for development of real time voice synthesis applications. The system is composed from a DSP coprocessor card, equipped with an TMS320C25 or TMS320C50 chip, voice acquisition module (ADDA2),host computer (IBM-PC compatible), software specific tools.

System specification for the integrated monitoring and surveillance system

International Nuclear Information System (INIS)

1997-09-01

This System Specification establishes the requirements for the Plutonium Focus Area (PFA) Integrated Monitoring and Surveillance System (IMSS). In this document, ''Integrated Monitoring and Surveillance System'' is used to describe the concept of integrated sensors, computers, personnel, and systems that perform the functions of sensing conditions, acquiring data, monitoring environmental safety and health, controlling and accounting for materials, monitoring material stability, monitoring container integrity, transferring data, and analyzing, reporting, and storing data. This concept encompasses systems (e.g. sensors, personnel, databases, etc.) that are already in place at the sites but may require modifications or additions to meet all identified surveillance requirements. The purpose of this System Specification is to provide Department of Energy (DOE) sites that store plutonium materials with a consolidation of all known requirements for the storage and surveillance of 3013 packages of stabilized plutonium metals and oxides. This compilation may be used (1) as a baseline for surveillance system design specifications where 3013 packages of stabilized plutonium metals and oxides will be stored and monitored; (2) as a checklist for evaluating existing surveillance systems to ensure that all requirements are met for the storage and surveillance of 3013 packages of stabilized plutonium metals and oxides; and (3) as a baseline for preparing procurement specifications tailored for site specific storage and surveillance of 3013 packages of stabilized plutonium metals and oxides

Exactly and completely integrable nonlinear dynamical systems

International Nuclear Information System (INIS)

Leznov, A.N.; Savel'ev, M.V.

1987-01-01

The survey is devoted to a consitent exposition of the group-algebraic methods for the integration of systems of nonlinear partial differential equations possessing a nontrivial internal symmetry algebra. Samples of exactly and completely integrable wave and evolution equations are considered in detail, including generalized (periodic and finite nonperiodic Toda lattice, nonlinear Schroedinger, Korteweg-de Vries, Lotka-Volterra equations, etc.) For exactly integrable systems the general solutions of the Cauchy and Goursat problems are given in an explicit form, while for completely integrable systems an effective method for the construction of their soliton solutions is developed. Application of the developed methods to a differential geometry problem of classification of the integrable manifolds embeddings is discussed. For exactly integrable systems the supersymmetric extensions are constructed. By the example of the generalized Toda lattice a quantization scheme is developed. It includes an explicit derivation of the corresponding Heisenberg operators and their desription in terms of the quantum algebras of the Hopf type. Among multidimensional systems the four-dimensional self-dual Yang-Mills equations are investigated most attentively with a goal of constructing their general solutions

INTEGRATED HSEQ MANAGEMENT SYSTEMS: DEVELOPMENTS AND TRENDS

OpenAIRE

Osmo Kauppila; Janne Härkönen; Seppo Väyrynen

2015-01-01

The integration of health and safety, environmental and quality (HSEQ) management systems has become a current topic in the 21st century, as the need for systems thinking has grown along with the number of management system standards. This study aims to map current developments and trends in integrated HSEQ management. Three viewpoints are taken: the current state of the main HSEQ management standards, research literature on integrated management systems (IMS), and a case study of an industry...

Advanced information processing system for advanced launch system: Avionics architecture synthesis

Science.gov (United States)

Lala, Jaynarayan H.; Harper, Richard E.; Jaskowiak, Kenneth R.; Rosch, Gene; Alger, Linda S.; Schor, Andrei L.

1991-01-01

The Advanced Information Processing System (AIPS) is a fault-tolerant distributed computer system architecture that was developed to meet the real time computational needs of advanced aerospace vehicles. One such vehicle is the Advanced Launch System (ALS) being developed jointly by NASA and the Department of Defense to launch heavy payloads into low earth orbit at one tenth the cost (per pound of payload) of the current launch vehicles. An avionics architecture that utilizes the AIPS hardware and software building blocks was synthesized for ALS. The AIPS for ALS architecture synthesis process starting with the ALS mission requirements and ending with an analysis of the candidate ALS avionics architecture is described.

Development of system integration technology for integral reactor

Energy Technology Data Exchange (ETDEWEB)

Chang, Moon Hee; Kang, D. J.; Kim, K. K. and others

1999-03-01

The objective of this report is to integrate the conceptual design of an integral reactor, SMART producing thermal energy of 330 MW, which will be utilized to supply energy for seawater desalination and small-scale power generation. This project also aims to develop system integration technology for effective design of the reactor. For the conceptual design of SMART, preliminary design requirements including the top-tier requirements and design bases were evaluated and established. Furthermore, in the view of the application of codes and standards to the SMART design, existing laws, codes and standards were analyzed and evaluated with respect to its applicability. As a part of this evaluation, directions and guidelines were proposed for the development of new codes and standards which shall be applied to the SMART design. Regarding the integration of SMART conceptual designs, major design activities and interfaces between design departments were established and coordinated through the design process. For the effective management of all design schedules, a work performance evaluation system was developed and applied to the design process. As the results of this activity, an integrated output of SMART designs was produced. Two additional scopes performed in this project include the preliminary economic analysis on the SMART utilization for seawater desalination, and the planning of verification tests for technology implemented into SMART and establishing development plan of the computer codes to be used for SMART design in the next phase. The technical cooperation with foreign country and international organization for securing technologies for integral reactor design and its application was coordinated and managed through this project. (author)

An integrative review of information systems and terminologies used in local health departments.

Science.gov (United States)

Olsen, Jeanette; Baisch, Mary Jo

2014-02-01

The purpose of this integrative review based on the published literature was to identify information systems currently being used by local health departments and to determine the extent to which standard terminology was used to communicate data, interventions, and outcomes to improve public health informatics at the local health department (LHD) level and better inform research, policy, and programs. Whittemore and Knafl's integrative review methodology was used. Data were obtained through key word searches of three publication databases and reference lists of retrieved articles and consulting with experts to identify landmark works. The final sample included 45 articles analyzed and synthesized using the matrix method. The results indicated a wide array of information systems were used by LHDs and supported diverse functions aligned with five categories: administration; surveillance; health records; registries; and consumer resources. Detail regarding specific programs being used, location or extent of use, or effectiveness was lacking. The synthesis indicated evidence of growing interest in health information exchange groups, yet few studies described use of data standards or standard terminology in LHDs. Research to address these gaps is needed to provide current, meaningful data that inform public health informatics research, policy, and initiatives at and across the LHD level. Coordination at a state or national level is recommended to collect information efficiently about LHD information systems that will inform improvements while minimizing duplication of efforts and financial burden. Until this happens, efforts to strengthen LHD information systems and policies may be significantly challenged.

Total Synthesis of Ionic Liquid Systems for Dissolution of Lunar Simulant

Science.gov (United States)

Sharpe, Robert J.; Karr, Laurel J.; Paley, Mark S.

2010-01-01

For purposes of Space Resource Utilization, work in the total synthesis of a new ionic liquid system for the extraction of oxygen and metals from lunar soil is studied and described. Reactions were carried out according to procedures found in the chemical literature, analyzed via Thin-Layer Chromatography and 1H Nuclear Magnetic Resonance Spectroscopy and purified via vacuum distillation and rotary evaporation. Upon final analysis via 1H NMR, it was found that while the intermediates of the synthesis had been achieved, unexpected side products were also present. The mechanisms and constraints of the synthesis are described as well as the final results of the project and recommendations for continued study

Systemic design methodologies for electrical energy systems analysis, synthesis and management

CERN Document Server

Roboam, Xavier

2012-01-01

This book proposes systemic design methodologies applied to electrical energy systems, in particular analysis and system management, modeling and sizing tools. It includes 8 chapters: after an introduction to the systemic approach (history, basics & fundamental issues, index terms) for designing energy systems, this book presents two different graphical formalisms especially dedicated to multidisciplinary devices modeling, synthesis and analysis: Bond Graph and COG/EMR. Other systemic analysis approaches for quality and stability of systems, as well as for safety and robustness analysis tools are also proposed. One chapter is dedicated to energy management and another is focused on Monte Carlo algorithms for electrical systems and networks sizing. The aim of this book is to summarize design methodologies based in particular on a systemic viewpoint, by considering the system as a whole. These methods and tools are proposed by the most important French research laboratories, which have many scientific partn...

Implementation of integrated management system

International Nuclear Information System (INIS)

Gaspar Junior, Joao Carlos A.; Fonseca, Victor Zidan da

2007-01-01

In present day exist quality assurance system, environment, occupational health and safety such as ISO9001, ISO14001 and OHSAS18001 and others standards will can create. These standards can be implemented and certified they guarantee one record system, quality assurance, documents control, operational control, responsibility definition, training, preparing and serve to emergency, monitoring, internal audit, corrective action, continual improvement, prevent of pollution, write procedure, reduce costs, impact assessment, risk assessment , standard, decree, legal requirements of municipal, state, federal and local scope. These procedure and systems when isolate applied cause many management systems and bureaucracy. Integration Management System reduce to bureaucracy, excess of documents, documents storage and conflict documents and easy to others standards implementation in future. The Integrated Management System (IMS) will be implemented in 2007. INB created a management group for implementation, this group decides planing, works, policy and advertisement. Legal requirements were surveyed, internal audits, pre-audits and audits were realized. INB is partially in accordance with ISO14001, OSHAS18001 standards. But very soon, it will be totally in accordance with this norms. Many studies and works were contracted to deal with legal requirements. This work have intention of show implementation process of ISO14001, OHSAS18001 and Integrated Management System on INB. (author)

PREFACE: Synthesis and integration of nanowires

Science.gov (United States)

Samuelson, L.

2006-06-01

The field of semiconductor nanowires has attracted much attention in recent years, from the areas of basic materials science, advanced characterization and technology, as well as from the perspective of the applications of nanowires. Research on large-sized whiskers and wires had already begun in the 1960s with the pioneering work of Wagner, as well as by other researchers. It was, however, in the early 1990s that Kenji Hiruma at Hitachi Central Research Laboratories in Japan first succeeded in developing methods for the growth of nanowires with dimensions on the scale of 10-100 nm, thereby initiating the field of growth and applications of nanowires, with a strong emphasis on epitaxial nucleation of nanowires on a single-crystalline substrate. Starting from the mid-1990s, the field developed very rapidly with the number of papers on the subject growing from ten per year to several thousand papers on the subject published annually today, although with a rather generous definition of the concept of nanowires. With this rapid development we have seen many new and different approaches to the growth of nanowires, technological advances leading to a more well-controlled formation of nanowires, new innovative methods for the characterization of structures, as well as a wealth of approaches towards the use of nanowires in electronics, photonics and sensor applications. This issue contains contributions from many different laboratories, each adding significant detail to the development of the field of research. The contributions cover issues such as basic growth, advanced characterization and technology, and application of nanowires. I would like to acknowledge the shared responsibilities for this special issue of Nanotechnology on the synthesis and integration of nanowires with my co-Editors, S Tong Lee and M Sunkara, as well as the highly professional support from Dr Nina Couzin, Dr Ian Forbes and the Nanotechnology team from the Institute of Physics Publishing.

AutoBayes Program Synthesis System Users Manual

Science.gov (United States)

Schumann, Johann; Jafari, Hamed; Pressburger, Tom; Denney, Ewen; Buntine, Wray; Fischer, Bernd

2008-01-01

Program synthesis is the systematic, automatic construction of efficient executable code from high-level declarative specifications. AutoBayes is a fully automatic program synthesis system for the statistical data analysis domain; in particular, it solves parameter estimation problems. It has seen many successful applications at NASA and is currently being used, for example, to analyze simulation results for Orion. The input to AutoBayes is a concise description of a data analysis problem composed of a parameterized statistical model and a goal that is a probability term involving parameters and input data. The output is optimized and fully documented C/C++ code computing the values for those parameters that maximize the probability term. AutoBayes can solve many subproblems symbolically rather than having to rely on numeric approximation algorithms, thus yielding effective, efficient, and compact code. Statistical analysis is faster and more reliable, because effort can be focused on model development and validation rather than manual development of solution algorithms and code.

Formal First Integrals of General Dynamical Systems

Directory of Open Access Journals (Sweden)

Jia Jiao

2016-01-01

Full Text Available The goal of this paper is trying to make a complete study on the integrability for general analytic nonlinear systems by first integrals. We will firstly give an exhaustive discussion on analytic planar systems. Then a class of higher dimensional systems with invariant manifolds will be considered; we will develop several criteria for existence of formal integrals and give some applications to illustrate our results at last.

An Integrated Library System: Preliminary Considerations.

Science.gov (United States)

Neroda, Edward

Noting difficulties experienced by small to medium sized colleges in acquiring integrated library computer systems, this position paper outlines issues related to the subject with the intention of increasing familiarity and interest in integrated library systems. The report includes: a brief review of technological advances as they relate to…

Three dimensional system integration

CERN Document Server

Papanikolaou, Antonis; Radojcic, Riko

2010-01-01

Three-dimensional (3D) integrated circuit (IC) stacking is the next big step in electronic system integration. It enables packing more functionality, as well as integration of heterogeneous materials, devices, and signals, in the same space (volume). This results in consumer electronics (e.g., mobile, handheld devices) which can run more powerful applications, such as full-length movies and 3D games, with longer battery life. This technology is so promising that it is expected to be a mainstream technology a few years from now, less than 10-15 years from its original conception. To achieve thi

Challenges in process integration of catalytic DC plasma synthesis of vertically aligned carbon nanofibres

International Nuclear Information System (INIS)

Melechko, Anatoli V; Pearce, Ryan C; Hensley, Dale K; Simpson, Michael L; McKnight, Timothy E

2011-01-01

The ability to synthesize free-standing, individual carbon nanofibres (CNFs) aligned perpendicularly to a substrate has enabled fabrication of a large array of devices with nanoscale functional elements, including electron field emission sources, electrochemical probes, neural interface arrays, scanning probes, gene delivery arrays and many others. This was made possible by development of a catalytic plasma process, with DC bias directing the alignment of nanofibres. Successful implementation of prototypical devices has uncovered numerous challenges in the integration of this synthesis process as one of the steps in device fabrication. This paper is dedicated to these engineering and fundamental difficulties that hinder further device development. Relatively high temperature for catalytic synthesis, electrical conductivity of the substrate to maintain DC discharge and other difficulties place restrictions on substrate material. Balancing non-catalytic carbon film deposition and substrate etching, non-uniformity of plasma due to growth of the high aspect ratio structures, plasma instabilities and other factors lead to challenges in controlling the plasma. Ultimately, controlling the atomistic processes at the catalyst nanoparticle (NP) and the behaviour of the NP is the central challenge of plasma nanosynthesis of vertically aligned CNFs.

The topology of integrable systems with incomplete fields

International Nuclear Information System (INIS)

Aleshkin, K R

2014-01-01

Liouville's theorem holds for Hamiltonian systems with complete Hamiltonian fields which possess a complete involutive system of first integrals; such systems are called Liouville-integrable. In this paper integrable systems with incomplete Hamiltonian fields are investigated. It is shown that Liouville's theorem remains valid in the case of a single incomplete field, while if the number of incomplete fields is greater, a certain analogue of the theorem holds. An integrable system on the algebra sl(3) is taken as an example. Bibliography: 11 titles

Synthesis of pneumatic controll systems

Directory of Open Access Journals (Sweden)

D. Nowak

2011-04-01

Full Text Available Currently, the basic tool for automating the production processes are the PLCs. However, in many areas application of the pneumaticcontrol systems may be more reasonable. The main factor determining choice of the control technology are costs. In the case of pneumaticsystems, the costs shall be determined by the number of elements used. Therefore, during the design works it is important to choose anappropriate method for the pneumatic control systems synthesis. The article presents the MTS method, which may be used for a discretetechnological processes modeling and PLC programming, as well as for a pneumatic control systems designing. An important element ofthe MTS method is the network of actions, which graphically presents an algorithm of the implemented process. Based on the actionnetwork and operating machine’s functional diagram, the diagram of different states is determinated, which graphically shows changes ofthe control system’s input and output signals. Analysis of the diagram of different states, makes it easy to determine a schematic equation, which shall be the basis for the control system implementation. Advantage of the MTS method is the lack of restrictions on the number of the control system’s input and output signals. The resulting solution is characterized by a minimum number of elements needed to implement the control system.

Synthesis of magnetic systems producing field with maximal scalar characteristics

International Nuclear Information System (INIS)

Klevets, Nickolay I.

2005-01-01

A method of synthesis of the magnetic systems (MSs) consisting of uniformly magnetized blocks is proposed. This method allows to synthesize MSs providing maximum value of any magnetic field scalar characteristic. In particular, it is possible to synthesize the MSs providing the maximum of a field projection on a given vector, a gradient of a field modulus and a gradient of a field energy on a given directing vector, a field magnitude, a magnetic flux through a given surface, a scalar product of a field or a force by a directing function given in some area of space, etc. The synthesized MSs provide maximal efficiency of permanent magnets utilization. The usage of the proposed method of MSs synthesis allows to change a procedure of projecting in principal, namely, to execute it according to the following scheme: (a) to choose the sizes, a form and a number of blocks of a system proceeding from technological (economical) reasons; (b) using the proposed synthesis method, to find an orientation of site magnetization providing maximum possible effect of magnet utilization in a system obtained in (a). Such approach considerably reduces a time of MSs projecting and guarantees maximal possible efficiency of magnets utilization. Besides it provides absolute assurance in 'ideality' of a MS design and allows to obtain an exact estimate of the limit parameters of a field in a working area of a projected MS. The method is applicable to a system containing the components from soft magnetic material with linear magnetic properties

Audio system using binaural synthesis for multimodal telepresence applications

DEFF Research Database (Denmark)

Madsen, Esben; Markovic, Milos; Olesen, Søren Krarup

2013-01-01

are implemented in a distributed manner. Body-tracking of all participants is provided through the system for the purpose of using binaural synthesis for directional sound. Head-worn microphones are used to capture sound, and the visitor is provided with directional sound through headphones. The visitor...

Wearable smart systems: from technologies to integrated systems.

Science.gov (United States)

Lymberis, A

2011-01-01

Wearable technology and integrated systems, so called Smart Wearable Systems (SWS) have demonstrated during the last 10-15 years significant advances in terms of, miniaturisation, seamless integration, data processing & communication, functionalisation and comfort. This is mainly due to the huge progress in sciences and technologies e.g. biomedical and micro & nano technologies, but also to a strong demand for new applications such as continuous personal health monitoring, healthy lifestyle support, human performance monitoring and support of professionals at risk. Development of wearable systems based of smart textile have, in addition, benefited from the eagerness of textile industry to develop new value-added apparel products like functionalized garments and smart clothing. Research and development in these areas has been strongly promoted worldwide. In Europe the major R&D activities were supported through the Information & Communication Technologies (ICT) priority of the R&D EU programs. The paper presents and discusses the main achievements towards integrated systems as well as future challenges to be met in order to reach a market with reliable and high value-added products.

Performance of integrated systems of automated roller shade systems and daylight responsive dimming systems

Energy Technology Data Exchange (ETDEWEB)

Park, Byoung-Chul; Choi, An-Seop; Jeong, Jae-Weon [Department of Architectural Engineering, Sejong University, Kunja-Dong, Kwangjin-Gu, Seoul (Korea, Republic of); Lee, Eleanor S. [Building Technologies Department, Lawrence Berkeley National Laboratory, Berkeley, CA (United States)

2011-03-15

Daylight responsive dimming systems have been used in few buildings to date because they require improvements to improve reliability. The key underlying factor contributing to poor performance is the variability of the ratio of the photosensor signal to daylight workplane illuminance in accordance with sun position, sky condition, and fenestration condition. Therefore, this paper describes the integrated systems between automated roller shade systems and daylight responsive dimming systems with an improved closed-loop proportional control algorithm, and the relative performance of the integrated systems and single systems. The concept of the improved closed-loop proportional control algorithm for the integrated systems is to predict the varying correlation of photosensor signal to daylight workplane illuminance according to roller shade height and sky conditions for improvement of the system accuracy. In this study, the performance of the integrated systems with two improved closed-loop proportional control algorithms was compared with that of the current (modified) closed-loop proportional control algorithm. In the results, the average maintenance percentage and the average discrepancies of the target illuminance, as well as the average time under 90% of target illuminance for the integrated systems significantly improved in comparison with the current closed-loop proportional control algorithm for daylight responsive dimming systems as a single system. (author)

Development of remote control integrator system on Tokamak

International Nuclear Information System (INIS)

Wu Yichun; Wang Lingzhi; Shu Shuangbao

2014-01-01

In order to meet with the requirement of electromagnetic diagnosis to the J-TEXT Tokamak, a remote control integrator system was developed. With modular design method, the integrator system is composed of the integrator cards, a control card, a linear power card and the BNC interface cards, and it uses the PC control soft- ware to conduct network control. An integrator system provides 32 integrator channels, and all integral channels have four kinds of integral time constants for remote selection and provide three kinds of integrator running control methods. According to laboratory and J-TEXT field testing, it shows that the output voltage range is -10-10 V, output noise is not more than 5 mV, and for the four kinds of integral time constants, the integral output drifts are all less than 5 mV within 100 s for each integrator channel. (authors)

Integrated management systems

DEFF Research Database (Denmark)

Jørgensen, Tine Herreborg; Remmen, Arne; Mellado, M. Dolores

2006-01-01

Different approaches to integration of management systems (ISO 9001, ISO 14001, OHSAS 18001 and SA 8000) with various levels of ambition have emerged. The tendency of increased compatibility between these standards has paved the road for discussions of, how to understand the different aspects of ...

Evaluation of mobile systems: an integrative framework.

NARCIS (Netherlands)

Högler, T.; Versendaal, J.; Batenburg, R.

2015-01-01

This work presents an integrative framework for the evaluation of mobile systems. In comparison to stationary systems, mobile systems have a bundle of specific singularities that should be considered for evaluation. Further analysis of existing approaches clarifies that an integrative approach for

Seamless integrated network system for wireless communication systems

NARCIS (Netherlands)

Wu, Gang; Mizuno, Mitsuhiko; Hase, Yoshihiro; Havinga, Paul J.M.

2006-01-01

To create a network that connects a plurality of wireless communication systems to create optimal systems for various environments, and that seamlessly integrates the resulting systems together in order to provide more efficient and advanced service in general. A network system that can seamlessly

Seamless integrated network system for wireless communication systems

NARCIS (Netherlands)

Wu, Gang; Mizuno, Mitsuhiko; Hase, Yoshihiro; Havinga, Paul J.M.

2002-01-01

To create a network that connects a plurality of wireless communication systems to create optimal systems for various environments, and that seamlessly integrates the resulting systems together in order to provide more efficient and advanced service in general. A network system that can seamlessly

Outcome mapping for health system integration

Directory of Open Access Journals (Sweden)

Tsasis P

2013-03-01

Full Text Available Peter Tsasis,1 Jenna M Evans,2 David Forrest,3 Richard Keith Jones4 1School of Health Policy and Management, Faculty of Health, York University, Toronto, Canada; 2Institute of Health Policy, Management and Evaluation, Faculty of Medicine, University of Toronto, Canada; 3Global Vision Consulting Ltd, Victoria, Canada; 4R Keith Jones and Associates, Victoria, Canada Abstract: Health systems around the world are implementing integrated care strategies to improve quality, reduce or maintain costs, and improve the patient experience. Yet few practical tools exist to aid leaders and managers in building the prerequisites to integrated care, namely a shared vision, clear roles and responsibilities, and a common understanding of how the vision will be realized. Outcome mapping may facilitate stakeholder alignment on the vision, roles, and processes of integrated care delivery via participative and focused dialogue among diverse stakeholders on desired outcomes and enabling actions. In this paper, we describe an outcome-mapping exercise we conducted at a Local Health Integration Network in Ontario, Canada, using consensus development conferences. Our preliminary findings suggest that outcome mapping may help stakeholders make sense of a complex system and foster collaborative capital, a resource that can support information sharing, trust, and coordinated change toward integration across organizational and professional boundaries. Drawing from the theoretical perspectives of complex adaptive systems and collaborative capital, we also outline recommendations for future outcome-mapping exercises. In particular, we emphasize the potential for outcome mapping to be used as a tool not only for identifying and linking strategic outcomes and actions, but also for studying the boundaries, gaps, and ties that characterize social networks across the continuum of care. Keywords: integrated care, integrated delivery systems, complex adaptive systems, social capital

How to assess and prepare health systems in low- and middle-income countries for integration of services-a systematic review.

Science.gov (United States)

Topp, Stephanie M; Abimbola, Seye; Joshi, Rohina; Negin, Joel

2018-03-01

Despite growing support for integration of frontline services, a lack of information about the pre-conditions necessary to integrate such services hampers the ability of policy makers and implementers to assess how feasible or worthwhile integration may be, especially in low- and middle-income countries (LMICs). We adopted a modified systematic review with aspects of realist review, including quantitative and qualitative studies that incorporated assessment of health system preparedness for and capacity to implement integrated services. We searched Medline via Ovid, Web of Science and the Cochrane library using terms adapted from Dudley and Garner's systematic review on integration in LMICs. From an initial list of 10 550 articles, 206 were selected for full-text review by two reviewers who independently reviewed articles and inductively extracted and synthesized themes related to health system preparedness. We identified five 'context' related categories and four health system 'capability' themes. The contextual enabling and constraining factors for frontline service integration were: (1) the organizational framework of frontline services, (2) health care worker preparedness, (3) community and client preparedness, (4) upstream logistics and (5) policy and governance issues. The intersecting health system capabilities identified were the need for: (1) sufficiently functional frontline health services, (2) sufficiently trained and motivated health care workers, (3) availability of technical tools and equipment suitable to facilitate integrated frontline services and (4) appropriately devolved authority and decision-making processes to enable frontline managers and staff to adapt integration to local circumstances. Moving beyond claims that integration is defined differently by different programs and thus unsuitable for comparison, this review demonstrates that synthesis is possible. It presents a common set of contextual factors and health system capabilities

Integrated management system

International Nuclear Information System (INIS)

Florescu, N.

2003-01-01

A management system is developed in order to reflect the needs of the business and to ensure that the objectives of the organization will be achieved. The process model and each individual process within the system then needs to identify the drives or requirements from external customers and stakeholders, regulations, and standards such as ISO and 50-C-Q. The processes are then developed to address these drivers. Developing the process in this way makes it fully integrated and capable of incorporating any new requirements. The International Standard (ISO 9000:2000) promotes the adoption of a process approach when developing, implementing and improving the effectiveness of a quality management system to enhance customer satisfaction by meeting customer requirements. The IAEA Code recognizes that the entire work is a process which can be planned, assessed and improved. For an organization to function effectively, numerous linked activities have to be identified and managed. By definition a process is an activity that using resources and taking into account all the constraints imposed executes the necessary operations which transform the inputs in outcomes. Running a system of processes within an organization, identification of the interaction between the processes and their management can be referred to as a 'process approach'. The advantage of such an approach is the ensuring of the ongoing control over the linkage between the individual processes composing the system as well as over their combination and interaction. Developing a management system implies: identification of the process which delivers Critical Success Factor (CSFs) of the business; identifying the support processes enabling the CSFs to be accomplished; identifying the processes that deliver the business fundamentals. An integrated management system should include all activities not only those related to Quality, Health and Safety. When developing an IMS it is necessary to identify all of the drivers

ACADEMIC INTEGRITY SUPPORT SYSTEM FOR UKRAINIAN UNIVERSITIES

Directory of Open Access Journals (Sweden)

V. G. Sherstjuk

2017-04-01

Full Text Available Purpose. Developing the methodology for providing academic integrity in the university. The methodology is based on Web-oriented academic integrity support system, developed by the authors, which enters into the information system of learning process control. Academic integrity support system is aimed at maintaining academic integrity as a basic institutional value, which will help to reduce corruption, plagiarism and other types of academic dishonesty. Methodology. The methodology of problem to solve is based on the development of the information system of education process control with the integral elements of quality control. The information subsystem of academic integrity support is its basic part. Findings. The proposed information system allows us to fulfill the following levels: educational process monitoring; audit of internal processes, which is necessary for developing the effective quality control system; assessment of achievements of educational process participants; formalization of the interaction of educational process participants. The system is aimed at the development of new academic society based on the following principles: open access to the information, at which the access of wide audience to the information provides participation, forming the sense of responsibility and social control; transparency of the information, by which its relevance, quality, reliability are meant; responsibility of all members of educational process; measurability, at which any action in educational process should be measured; detail of describing the actions, results and processes; support, which is meant by automatic tools of the realization of the principles of open access to the information, transparency of the information, responsibility of all participants of educational process, measurability, detail, support. The practical realization of information system is based on the development of a common repository of university information. The

Development of Spreadsheet-Based Integrated Transaction Processing Systems and Financial Reporting Systems

Science.gov (United States)

Ariana, I. M.; Bagiada, I. M.

2018-01-01

Development of spreadsheet-based integrated transaction processing systems and financial reporting systems is intended to optimize the capabilities of spreadsheet in accounting data processing. The purpose of this study are: 1) to describe the spreadsheet-based integrated transaction processing systems and financial reporting systems; 2) to test its technical and operational feasibility. This study type is research and development. The main steps of study are: 1) needs analysis (need assessment); 2) developing spreadsheet-based integrated transaction processing systems and financial reporting systems; and 3) testing the feasibility of spreadsheet-based integrated transaction processing systems and financial reporting systems. The technical feasibility include the ability of hardware and operating systems to respond the application of accounting, simplicity and ease of use. Operational feasibility include the ability of users using accounting applications, the ability of accounting applications to produce information, and control applications of the accounting applications. The instrument used to assess the technical and operational feasibility of the systems is the expert perception questionnaire. The instrument uses 4 Likert scale, from 1 (strongly disagree) to 4 (strongly agree). Data were analyzed using percentage analysis by comparing the number of answers within one (1) item by the number of ideal answer within one (1) item. Spreadsheet-based integrated transaction processing systems and financial reporting systems integrate sales, purchases, and cash transaction processing systems to produce financial reports (statement of profit or loss and other comprehensive income, statement of changes in equity, statement of financial position, and statement of cash flows) and other reports. Spreadsheet-based integrated transaction processing systems and financial reporting systems is feasible from the technical aspects (87.50%) and operational aspects (84.17%).

System analysis of dry black liquor gasification based synthetic gas production comparing oxygen and air blown gasification systems

International Nuclear Information System (INIS)

Naqvi, Muhammad; Yan, Jinyue; Dahlquist, Erik

2013-01-01

Highlights: ► Circulating fluidized bed system for black liquor gasification with direct causticization. ► Effects of gasifying medium i.e. oxygen or air, on gasification are studied. ► Direct causticization eliminates energy intensive limekiln reducing biomass use. ► Results show 10% higher SNG production from O 2 blown system than air blown system. ► SNG production is higher in O 2 blown system than air blown system. - Abstract: The black liquor gasification based bio-fuel production at chemical pulp mill is an attractive option to replace conventional recovery boilers increasing system energy efficiency. The present paper studies circulating fluidized bed system with direct causticization using TiO 2 for the gasification of the black liquor to the synthesis gas. The advantage of using direct causticization is the elimination of energy-intensive lime kiln which is an integral part of the conventional black liquor recovery system. The study evaluates the effects of gasifying medium i.e. oxygen or air, on the fluidized bed gasification system, the synthesis gas composition, and the downstream processes for the synthesis gas conversion to the synthetic natural gas (SNG). The results showed higher synthetic natural gas production potential with about 10% higher energy efficiency using oxygen blown gasification system than the air blown system. From the pulp mill integration perspective, the material and energy balance results in better integration of air blown system than the oxygen blown system, e.g. less steam required to be generated in the power boiler, less electricity import, and less additional biomass requirement. However, the air blown system still requires a significant amount of energy in terms of the synthesis gas handling and gas upgrading using the nitrogen rejection system

An Integrated Knowledge Management System

Directory of Open Access Journals (Sweden)

Vasile Mazilescu

2014-11-01

Full Text Available The aim of this paper is to present a Knowledge Management System based on Fuzzy Logic (FLKMS, a real-time expert system to meet the challenges of the dynamic environment. The main feature of our integrated shell FLKMS is that it models and integrates the temporal relationships between the dynamic of the evolution of an economic process with some fuzzy inferential methods, using a knowledge model for control, embedded within the expert system’s operational knowledge base.

Design of 3D integrated circuits and systems

CERN Document Server

Sharma, Rohit

2014-01-01

Three-dimensional (3D) integration of microsystems and subsystems has become essential to the future of semiconductor technology development. 3D integration requires a greater understanding of several interconnected systems stacked over each other. While this vertical growth profoundly increases the system functionality, it also exponentially increases the design complexity. Design of 3D Integrated Circuits and Systems tackles all aspects of 3D integration, including 3D circuit and system design, new processes and simulation techniques, alternative communication schemes for 3D circuits and sys

Multilevel power distribution synthesis for a movable flux mapping system

International Nuclear Information System (INIS)

Bollacasa, D.; Terney, W.B.; Vincent, G.F.; Dziadosz, D.; Schleicher, T.

1992-01-01

A Computer Software package has been developed to support the synthesis of the 3-dimensional power distribution from detector signals from a movable flux mapping system. The power distribution synthesis is based on methodology developed for fixed incore detectors. The full core solution effectively couples all assemblies in the core whether they are instrumented or not. The solution is not subject to approximations for the treatment of assemblies where a measurement cannot be made and provides an accurate representation of axial variations which may be induced by axial blankets, burnable absorber cut back regions and axially zoned flux suppression rods

The formation and influence of carbon on cobalt-based Fischer-Tropsch synthesis catalysts : an integrated review

NARCIS (Netherlands)

Moodley, D.J.; Loosdrecht, van de J.; Saib, A.M.; Niemantsverdriet, J.W.; Davis, B.H.; Occelli, M.L.; Speight, J.G.

2010-01-01

Cobalt-based Fischer-Tropsch synthesis (FTS) catalysts are the systems of choice for use in gas-to-liquid (GTL) processes. As with most catalysts, cobalt systems gradually lose their activity with increasing time on stream. There are various mechanisms that have been proposed for the deactivation of

About the methodology of system synthesis of decision-makings and its procedures automation

Directory of Open Access Journals (Sweden)

D. P. Oleynikov

2016-01-01

Full Text Available Purpose. The problem qualitative assessment of technologies and innovations, which cannot be solved without modern methods and decision support systems, is currently particularly relevant. The reason for this is the increasingly increasing amount of heterogeneous information, which should take into account the decision maker. Reduction of the allowable period of decision-making also has a signifi cant impact on this process. These reasons are refl ected in the problems of network-centric warfare, nuclear management, forecasting, and conceptual design. It actualizes the problem of the synthesis of new methods of decision-making that will effectively solve the problem of choice of alternatives in those problem areas where the application of existing methods of decision-making is unfounded or inadmissible. The complexity of the process of creation of new decision-making methods caused by the high degree of utilization of cognitive processes. In accordance with the system-wide development trends the designer in the process of synthesis of the decision-makings should take a system (or group of systems which implements certain cognitive operations. The first step towards the creation of such a group of systems is the development of methodology of the system synthesis of decision-makings.Materials and methods. The scope of research are approaches to the synthesis of systems, and in particular – the synthesis of decision-makings. On the basis of multidimensional analysis and generalization of approach the methodology was developed, which consists of the main stages - goal setting, goal achievement and variations of the target system. Within each of the stages a wide variation of operations is possible to be used, which applied depending on the available data, obtained from the analysis of the subject area. With the use of the methodology obtained a number ofdecision-making methods, and their creation was carried out without

46 CFR 111.50-2 - Systems integration.

Science.gov (United States)

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Systems integration. 111.50-2 Section 111.50-2 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Overcurrent Protection § 111.50-2 Systems integration. The electrical characteristics of each...

Spore coat protein synthesis in cell-free systems from sporulating cells of Bacillus subtilis.

Science.gov (United States)

Nakayama, T; Munoz, L E; Sadaie, Y; Doi, R H

1978-09-01

Cell-free systems for protein synthesis were prepared from Bacillus subtilis 168 cells at several stages of sporulation. Immunological methods were used to determine whether spore coat protein could be synthesized in the cell-free systems prepared from sporulating cells. Spore coat protein synthesis first occurred in extracts from stage t2 cells. The proportion of spore coat protein to total proteins synthesized in the cell-free systems was 2.4 and 3.9% at stages t2 and t4, respectively. The sodium dodecyl sulfate-urea-polyacrylamide gel electrophoresis patterns of immunoprecipitates from the cell-free systems showed the complete synthesis of an apparent spore coat protein precursor (molecular weight, 25,000). A polypeptide of this weight was previously identified in studies in vivo (L.E. Munoz, Y. Sadaie, and R.H. Doi, J. Biol. Chem., in press). The synthesis in vitro of polysome-associated nascent spore coat polypeptides with varying molecular weights up to 23,000 was also detected. These results indicate that the spore coat protein may be synthesized as a precursor protein. The removal of proteases in the crude extracts by treatment with hemoglobin-Sepharose affinity techniques may be preventing the conversion of the large 25,000-dalton precursor to the 12,500-dalton mature spore coat protein.

Schedulability Analysis and Optimization for the Synthesis of Multi-Cluster Distributed Embedded Systems

DEFF Research Database (Denmark)

Pop, Paul; Eles, Petru; Peng, Zebo

2003-01-01

We present an approach to schedulability analysis for the synthesis of multi-cluster distributed embedded systems consisting of time-triggered and event-triggered clusters, interconnected via gateways. We have also proposed a buffer size and worst case queuing delay analysis for the gateways......, responsible for routing inter-cluster traffic. Optimization heuristics for the priority assignment and synthesis of bus access parameters aimed at producing a schedulable system with minimal buffer needs have been proposed. Extensive experiments and a real-life example show the efficiency of our approaches....

Schedulability Analysis and Optimization for the Synthesis of Multi-Cluster Distributed Embedded Systems

DEFF Research Database (Denmark)

Pop, Paul; Eles, Petru; Peng, Zebo

2003-01-01

An approach to schedulability analysis for the synthesis of multi-cluster distributed embedded systems consisting of time-triggered and event-triggered clusters, interconnected via gateways, is presented. A buffer size and worst case queuing delay analysis for the gateways, responsible for routing...... inter-cluster traffic, is also proposed. Optimisation heuristics for the priority assignment and synthesis of bus access parameters aimed at producing a schedulable system with minimal buffer needs have been proposed. Extensive experiments and a real-life example show the efficiency of the approaches....

INTEGRATED HSEQ MANAGEMENT SYSTEMS: DEVELOPMENTS AND TRENDS

Directory of Open Access Journals (Sweden)

Osmo Kauppila

2015-06-01

Full Text Available The integration of health and safety, environmental and quality (HSEQ management systems has become a current topic in the 21st century, as the need for systems thinking has grown along with the number of management system standards. This study aims to map current developments and trends in integrated HSEQ management. Three viewpoints are taken: the current state of the main HSEQ management standards, research literature on integrated management systems (IMS, and a case study of an industry-led HSEQ cluster in Northern Finland. The results demonstrate that some of the most prominent current trends are the harmonization of the high level structure of management systems by ISO, the evaluation of IMS, accounting for the supply chain in HSEQ issues, and sustainability and risk management. The results of the study can be used by practitioners to get a view of the current state of HSEQ management systems and their integration, and by researchers to seek out potential directions for HSEQ and IMS related research.

Controller synthesis for negative imaginary systems: a data driven approach

KAUST Repository

Mabrok, Mohamed; Petersen, Ian R.

2016-01-01

-driven controller synthesis methodology for NI systems is presented. In this approach, measured frequency response data of the plant is used to construct the controller frequency response at every frequency by minimising a cost function. Then, this controller

Systems integration of business systems. Business system ni kanshite

Energy Technology Data Exchange (ETDEWEB)

Furukawa, H [Nippon Steel Corp., Tokyo (Japan)

1991-09-26

System integration (SI) is defined as combining hardwares and softwares as the infrastructures with know-hows for their use comprehensively to respond to high-level needs of users. This paper reports the features of an SI being developed by a company (E Company), its concept on the systematized development methodology, and the conceptual models. With the primary policy placed on creative integration standing on customers positions, the SI concept comprises three parts of models for evaluations as seen from the customers, evaluations as seen from the E Company, and the development object systems to link both parts. The third part is further consisted of several lower hierarchies including a customer controlled system hierarchy (this enables customers to control the system through visualization, for example, and includes three logic models (multiple solution selection, optimal solution under restricted conditions, and numerical solution)). 2 refs., 9 figs.

Laser and photonic systems design and integration

CERN Document Server

Nof, Shimon Y; Cheng, Gary J

2014-01-01

New, significant scientific discoveries in laser and photonic technologies, systems perspectives, and integrated design approaches can improve even further the impact in critical areas of challenge. Yet this knowledge is dispersed across several disciplines and research arenas. Laser and Photonic Systems: Design and Integration brings together a multidisciplinary group of experts to increase understanding of the ways in which systems perspectives may influence laser and photonic innovations and application integration.By bringing together chapters from leading scientists and technologists, ind

Continuous Flow Controlled Synthesis of Gold Nanoparticles Using Pulsed Mixing Microfluidic System

Directory of Open Access Journals (Sweden)

Guojun Liu

2015-01-01

Full Text Available To prepare the gold nanoparticles (AuNPs with uniform sizes, fine morphology, and good monodispersity, a pulsed mixing microfluidic system based on PZT actuation was presented. The system includes PZT micropump and Y type micromixer. By adjusting voltage (entrance flow rate, pulsed frequency, phase, and other parameters, a variety of mixing modes can be achieved, so as to realize the controllable synthesis of nanoparticles in a certain range. By numerical simulation and analysis, the channel section size, entrance angle, and pulse frequency were optimized. Based on the optimized structure and working parameters, the test prototype has been manufactured in lab, and the related synthesis tests of AuNPs were carried out. The test results indicate that AuNPs with uniform morphology and good monodispersity can be synthesized using the system with the section size (0.4 mm × 0.4 mm, the entrance channel angle (60° under condition of the pulsed frequency (300 Hz, and the entrance flow rate (4 mL/min. The average diameter and its standard deviation of AuNPs synthesized were 21.6 nm, 4.83 nm, respectively. The research work above can be applied to the fields such as the controlled synthesis of noble metal nanoparticles, biomedicine, and microchemical system.

Synthesis of complex compounds in the system [ReOG5]2--thiosemicarbazone acetone-Hg-acetone

International Nuclear Information System (INIS)

Amindzhanov, A.A.; Kurbanov, N.M.

1993-01-01

Present article is devoted to synthesis of complex compounds in the system [ReOG 5 ] 2- -thiosemicarbazone acetone-Hg-acetone. The literature data on complex compounds of various metals with thiosemicarbazone was summarized. The synthesis of complex compounds in the system [ReOG 5 ] 2- -thiosemicarbazone acetone-Hg-acetone was conducted. The complex compounds of rhenium with methyl ident thiosemicarbazone were synthesized.

Nonlinear dynamics non-integrable systems and chaotic dynamics

CERN Document Server

Borisov, Alexander

2017-01-01

This monograph reviews advanced topics in the area of nonlinear dynamics. Starting with theory of integrable systems – including methods to find and verify integrability – the remainder of the book is devoted to non-integrable systems with an emphasis on dynamical chaos. Topics include structural stability, mechanisms of emergence of irreversible behaviour in deterministic systems as well as chaotisation occurring in dissipative systems.

Integrating CLIPS applications into heterogeneous distributed systems

Science.gov (United States)

Adler, Richard M.

1991-01-01

SOCIAL is an advanced, object-oriented development tool for integrating intelligent and conventional applications across heterogeneous hardware and software platforms. SOCIAL defines a family of 'wrapper' objects called agents, which incorporate predefined capabilities for distributed communication and control. Developers embed applications within agents and establish interactions between distributed agents via non-intrusive message-based interfaces. This paper describes a predefined SOCIAL agent that is specialized for integrating C Language Integrated Production System (CLIPS)-based applications. The agent's high-level Application Programming Interface supports bidirectional flow of data, knowledge, and commands to other agents, enabling CLIPS applications to initiate interactions autonomously, and respond to requests and results from heterogeneous remote systems. The design and operation of CLIPS agents are illustrated with two distributed applications that integrate CLIPS-based expert systems with other intelligent systems for isolating and mapping problems in the Space Shuttle Launch Processing System at the NASA Kennedy Space Center.

Synthesis of nanofibrous ZnO by magnetron sputtering and its integration in dye-sensitized solar cells

International Nuclear Information System (INIS)

Ghimpu, L.; Tiginyanu, I.; Pauporte, T.; Guerin, V.M.; Lupan, O.

2013-01-01

This work demonstrates a cost-effective synthesis of nanofibrous ZnO layers by a magnetron sputtering. We present the results of layer characterization by scanning electron microscopy, X-ray diffraction, energy dispersive X-ray spectrometry, Raman spectroscopy, and photoluminescence which are indicative of good structural properties of the layers. The nanofibrous ZnO layers proves good structural properties offering a new nanomaterial for dye-sensitized solar cells (DSCs) application. Their successful integration in DSC for solar energy conversion is demonstrated by impedance spectroscopy, and photo-current-voltage (J-V) studies.

First integral method for an oscillator system

Directory of Open Access Journals (Sweden)

Xiaoqian Gong

2013-04-01

Full Text Available In this article, we consider the nonlinear Duffing-van der Pol-type oscillator system by means of the first integral method. This system has physical relevance as a model in certain flow-induced structural vibration problems, which includes the van der Pol oscillator and the damped Duffing oscillator etc as particular cases. Firstly, we apply the Division Theorem for two variables in the complex domain, which is based on the ring theory of commutative algebra, to explore a quasi-polynomial first integral to an equivalent autonomous system. Then, through solving an algebraic system we derive the first integral of the Duffing-van der Pol-type oscillator system under certain parametric condition.

Specification and Generation of Adapters for System Integration

NARCIS (Netherlands)

Mooij, A.J.; Voorhoeve, M.

2013-01-01

Large systems-of-systems are developed by integrating several smaller systems that have been developed independently. System integration often requires adaptation mechanisms for bridging any technical incompatibilities between the systems. In order to develop adapters in a faster way, we study ways

A robot-assisted synthesis system applied to 11C-alkylations

International Nuclear Information System (INIS)

Appelquist, G.; Bohm, C.; Eriksson, H.; Halldin, C.; Stone-Elander, S.

1990-01-01

A robot-based system for the production of radiopharmaceuticals has been developed, which consists of a 7-axis SCARA robot, supporting equipment, a synthesis module, and a PC-AT personal computer for system control. A Multifunction Editor (MFE) acts as the system controller and is a development tool as well. Robot movement can be controlled via keyboard, mouse, or remote control box, and procedures can be saved and edited for future use

Parametric Synthesis of Automatic Control System of Industrial Robot Manipulator in Compliance with Requirements of Robust Quality

Directory of Open Access Journals (Sweden)

A. A. Nesenchuk

2004-01-01

Full Text Available The paper considers an application of a root-locus method for synthesis of dynamic systems with uncertainty that meet the requirements of pre-set quality. This method is used for parametric synthesis of automatic control system of industrial robot manipulator that is used for transportation of engineering products. The synthesis takes place under conditions of substantial changes in inertia moment of robot load. As a result of investigations it is possible to determine range of values of variable parameter that ensures the required quality of control system operation. A system of computer programs has been developed in order to solve the problem.

CTBT Integrated Verification System Evaluation Model

Energy Technology Data Exchange (ETDEWEB)

Edenburn, M.W.; Bunting, M.L.; Payne, A.C. Jr.

1997-10-01

Sandia National Laboratories has developed a computer based model called IVSEM (Integrated Verification System Evaluation Model) to estimate the performance of a nuclear detonation monitoring system. The IVSEM project was initiated in June 1994, by Sandia`s Monitoring Systems and Technology Center and has been funded by the US Department of Energy`s Office of Nonproliferation and National Security (DOE/NN). IVSEM is a simple, top-level, modeling tool which estimates the performance of a Comprehensive Nuclear Test Ban Treaty (CTBT) monitoring system and can help explore the impact of various sensor system concepts and technology advancements on CTBT monitoring. One of IVSEM`s unique features is that it integrates results from the various CTBT sensor technologies (seismic, infrasound, radionuclide, and hydroacoustic) and allows the user to investigate synergy among the technologies. Specifically, IVSEM estimates the detection effectiveness (probability of detection) and location accuracy of the integrated system and of each technology subsystem individually. The model attempts to accurately estimate the monitoring system`s performance at medium interfaces (air-land, air-water) and for some evasive testing methods such as seismic decoupling. This report describes version 1.2 of IVSEM.

Synthesis of Optimal Isolation Systems of Hand-Transmitted Vibration

Directory of Open Access Journals (Sweden)

Marek Książek

1997-01-01

Full Text Available In this article a procedure is presented for the analytical synthesis of optimal vibration isolation for a hand-arm system subjected to stochastic excitation. A general approach is discussed for a selected vibration isolation criterion. The general procedure is illustrated by analytical examples for different hand-arm systems described by their driving-point impedances. The influence of particular forms of excitation and the structure of the vibroisolated hand-arm systems on the resultant vibration isolation is then discussed. Some numerical examples illustrating the procedure have also been included.

Integration of electronic document management system with other systems in a company

OpenAIRE

Pintar, Matej

2016-01-01

This master's thesis presents specific model of integration between electronic document management system and other systems in a medium-sized company in Slovenia. The introduction part of the thesis begins with theoretical basis of the research, which is the integration of computer systems. The introduction part is folowed by presentation of a concrete electronic document management system EBA DMS. Central part of the master's thesis presents different methods of integration of electronic doc...

Integrated management system laying a foundation for excellence

Energy Technology Data Exchange (ETDEWEB)

Brissette, S.; Vincent, D. [Bruce Power, Tiverton, Ontario (Canada)], E-mail: Derek.VINCENT@brucepower.com

2009-07-01

Integration in its simplest form involves seamless coordination between organizational elements such as organization structure, processes, systems and documents. This paper discusses the concept of integration in regards to managed systems and examines practical issues of marrying evolving standards to organizational design and overall governance. Bruce Power's experience in developing its Management System into a more integrated approach is described. Leadership sponsorship of an integrated programmatic approach using a Governance, Oversight, Support and Perform (GOSP) model of accountability framework within the Management System has been a critical success factor in Bruce Power's journey towards achieving operational excellence. (author)

Integrated management system laying a foundation for excellence

International Nuclear Information System (INIS)

Brissette, S.; Vincent, D.

2009-01-01

Integration in its simplest form involves seamless coordination between organizational elements such as organization structure, processes, systems and documents. This paper discusses the concept of integration in regards to managed systems and examines practical issues of marrying evolving standards to organizational design and overall governance. Bruce Power's experience in developing its Management System into a more integrated approach is described. Leadership sponsorship of an integrated programmatic approach using a Governance, Oversight, Support and Perform (GOSP) model of accountability framework within the Management System has been a critical success factor in Bruce Power's journey towards achieving operational excellence. (author)

Formalisms for reuse and systems integration

CERN Document Server

Rubin, Stuart

2015-01-01

Reuse and integration are defined as synergistic concepts, where reuse addresses how to minimize redundancy in the creation of components; while, integration focuses on component composition. Integration supports reuse and vice versa. These related concepts support the design of software and systems for maximizing performance while minimizing cost. Knowledge, like data, is subject to reuse; and, each can be interpreted as the other. This means that inherent complexity, a measure of the potential utility of a system, is directly proportional to the extent to which it maximizes reuse and integration. Formal methods can provide an appropriate context for the rigorous handling of these synergistic concepts. Furthermore, formal languages allow for non ambiguous model specification; and, formal verification techniques provide support for insuring the validity of reuse and integration mechanisms.   This edited book includes 12 high quality research papers written by experts in formal aspects of reuse and integratio...

Integrated Main Propulsion System Performance Reconstruction Process/Models

Science.gov (United States)

Lopez, Eduardo; Elliott, Katie; Snell, Steven; Evans, Michael

2013-01-01

The Integrated Main Propulsion System (MPS) Performance Reconstruction process provides the MPS post-flight data files needed for postflight reporting to the project integration management and key customers to verify flight performance. This process/model was used as the baseline for the currently ongoing Space Launch System (SLS) work. The process utilizes several methodologies, including multiple software programs, to model integrated propulsion system performance through space shuttle ascent. It is used to evaluate integrated propulsion systems, including propellant tanks, feed systems, rocket engine, and pressurization systems performance throughout ascent based on flight pressure and temperature data. The latest revision incorporates new methods based on main engine power balance model updates to model higher mixture ratio operation at lower engine power levels.

Coupling of glycerol processing with Fischer-Tropsch synthesis for production of liquid fuels

DEFF Research Database (Denmark)

Simonetti, D.A.; Rass-Hansen, Jeppe; Kunkes, E.L.

2007-01-01

Liquid alkanes can be produced directly from glycerol by an integrated process involving catalytic conversion to H-2/CO gas mixtures (synthesis gas) combined with Fischer-Tropsch synthesis. Synthesis gas can be produced at high rates and selectivities suitable for Fischer-Tropsch synthesis (H-2/CO...... between 1.0 and 1.6) from concentrated glycerol feed solutions at low temperatures (548 K) and high pressures (1-17 bar) over a 10 wt% Pt-Re/C catalyst with an atomic Pt : Re ratio of 1 : 1. The primary oxygenated hydrocarbon intermediates formed during conversion of glycerol to synthesis gas are ethanol...... in the liquid organic effluent stream and increasing the selectivity to C5+ alkanes by a factor of 2 ( from 0.30 to 0.60). Catalytic conversion of glycerol and Fischer-Tropsch synthesis were coupled in a two-bed reactor system consisting of a Pt-Re/C catalyst bed followed by a Ru/TiO2 catalyst bed...

Optimal planning of integrated multi-energy systems

DEFF Research Database (Denmark)

van Beuzekom, I.; Gibescu, M.; Pinson, Pierre

2017-01-01

In this paper, a mathematical approach for the optimal planning of integrated energy systems is proposed. In order to address the challenges of future, RES-dominated energy systems, the model deliberates between the expansion of traditional energy infrastructures, the integration...... and sustainability goals for 2030 and 2045. Optimal green- and brownfield designs for a district's future integrated energy system are compared using a one-step, as well as a two-step planning approach. As expected, the greenfield designs are more cost efficient, as their results are not constrained by the existing...

Markov modeling and reliability analysis of urea synthesis system of a fertilizer plant

Science.gov (United States)

Aggarwal, Anil Kr.; Kumar, Sanjeev; Singh, Vikram; Garg, Tarun Kr.

2015-12-01

This paper deals with the Markov modeling and reliability analysis of urea synthesis system of a fertilizer plant. This system was modeled using Markov birth-death process with the assumption that the failure and repair rates of each subsystem follow exponential distribution. The first-order Chapman-Kolmogorov differential equations are developed with the use of mnemonic rule and these equations are solved with Runga-Kutta fourth-order method. The long-run availability, reliability and mean time between failures are computed for various choices of failure and repair rates of subsystems of the system. The findings of the paper are discussed with the plant personnel to adopt and practice suitable maintenance policies/strategies to enhance the performance of the urea synthesis system of the fertilizer plant.

Reconceptualizing children's complex discharge with health systems theory: novel integrative review with embedded expert consultation and theory development.

Science.gov (United States)

Noyes, Jane; Brenner, Maria; Fox, Patricia; Guerin, Ashleigh

2014-05-01

To report a novel review to develop a health systems model of successful transition of children with complex healthcare needs from hospital to home. Children with complex healthcare needs commonly experience an expensive, ineffectual and prolonged nurse-led discharge process. Children gain no benefit from prolonged hospitalization and are exposed to significant harm. Research to enable intervention development and process evaluation across the entire health system is lacking. Novel mixed-method integrative review informed by health systems theory. DATA  CINAHL, PsychInfo, EMBASE, PubMed, citation searching, personal contact. REVIEW  Informed by consultation with experts. English language studies, opinion/discussion papers reporting research, best practice and experiences of children, parents and healthcare professionals and purposively selected policies/guidelines from 2002-December 2012 were abstracted using Framework synthesis, followed by iterative theory development. Seven critical factors derived from thirty-four sources across five health system levels explained successful discharge (new programme theory). All seven factors are required in an integrated care pathway, with a dynamic communication loop to facilitate effective discharge (new programme logic). Current health system responses were frequently static and critical success factors were commonly absent, thereby explaining ineffectual discharge. The novel evidence-based model, which reconceptualizes 'discharge' as a highly complex longitudinal health system intervention, makes a significant contribution to global knowledge to drive practice development. Research is required to develop process and outcome measures at different time points in the discharge process and future trials are needed to determine the effectiveness of integrated health system discharge models. © 2013 John Wiley & Sons Ltd.

Synthesis of Fault-Tolerant Embedded Systems with Checkpointing and Replication

DEFF Research Database (Denmark)

Izosimov, Viacheslav; Pop, Paul; Eles, Petru

2006-01-01

We present an approach to the synthesis of fault-tolerant hard real-time systems for safety-critical applications. We use checkpointing with rollback recovery and active replication for tolerating transient faults. Processes are statically scheduled and communications are performed using the time...

Synthesis of the ABCDEFG ring system of maitotoxin.

Science.gov (United States)

Nicolaou, K C; Aversa, Robert J; Jin, Jian; Rivas, Fatima

2010-05-19

Maitotoxin (1) continues to fascinate scientists not only because of its size and potent neurotoxicity but also due to its molecular architecture. To provide further support for its structure and facilitate fragment-based biological studies, we developed an efficient chemical synthesis of the ABCDEFG segment 3 of maitotoxin. (13)C NMR chemical shift comparisons of synthetic 3 with the corresponding values for the same carbons of maitotoxin revealed a close match, providing compelling evidence for the correctness of the originally assigned structure to this polycyclic system of the natural product. The synthetic strategy for the synthesis of 3 relied heavily on our previously developed furan-based technology involving sequential Noyori asymmetric reduction and Achmatowicz rearrangement for the construction of the required tetrahydropyran building blocks, and employed a B-alkyl Suzuki coupling and a Horner-Wadsworth-Emmons olefination to accomplish their assembly and elaboration to the final target molecule.

Russian and Foreign Experience of Integration of Agent-Based Models and Geographic Information Systems

Directory of Open Access Journals (Sweden)

Konstantin Anatol’evich Gulin

2016-11-01

Full Text Available The article provides an overview of the mechanisms of integration of agent-based models and GIS technology developed by Russian and foreign researchers. The basic framework of the article is based on critical analysis of domestic and foreign literature (monographs, scientific articles. The study is based on the application of universal scientific research methods: system approach, analysis and synthesis, classification, systematization and grouping, generalization and comparison. The article presents theoretical and methodological bases of integration of agent-based models and geographic information systems. The concept and essence of agent-based models are explained; their main advantages (compared to other modeling methods are identified. The paper characterizes the operating environment of agents as a key concept in the theory of agent-based modeling. It is shown that geographic information systems have a wide range of information resources for calculations, searching, modeling of the real world in various aspects, acting as an effective tool for displaying the agents’ operating environment and allowing to bring the model as close as possible to the real conditions. The authors also focus on a wide range of possibilities for various researches in different spatial and temporal contexts. Comparative analysis of platforms supporting the integration of agent-based models and geographic information systems has been carried out. The authors give examples of complex socio-economic models: the model of a creative city, humanitarian assistance model. In the absence of standards for research results description, the authors focus on the models’ elements such as the characteristics of the agents and their operation environment, agents’ behavior, rules of interaction between the agents and the external environment. The paper describes the possibilities and prospects of implementing these models

Improvement of Engineering Work Efficiency through System Integration

International Nuclear Information System (INIS)

Lee, Sangdae; Jo, Sunghan; Hyun, Jinwoo

2016-01-01

This paper presents the concept of developing an integrated engineering system for ER to improve efficiency and utilization of engineering system. Each process including computer system and database was introduced separately by each department at that different time. Each engineering process has a close relation with other engineering processes. The introduction of processes in a different time has caused the several problems such as lack of interrelationship between engineering processes, lack of integration fleet-wide statistical data, lack of the function of data comparison among plants and increase of access time by different access location on internet. These problems have caused inefficiency of engineering system utilization to get proper information and degraded engineering system utilization. KHNP has introduced and conducted advanced engineering processes to maintain equipment effectively in a highly reliable condition since 2000s. But engineering systems for process implementation have been developed in each department at a different time. This has caused the problems of process inefficiency and data discordance. Integrated Engineering System(IES) to integrate dispersed engineering processes will improve work efficiency and utilization of engineering system because integration system would enable engineer to get total engineering information easily and do engineering work efficiently

Improvement of Engineering Work Efficiency through System Integration

Energy Technology Data Exchange (ETDEWEB)

Lee, Sangdae; Jo, Sunghan; Hyun, Jinwoo [KHNP CRI, Daejeon (Korea, Republic of)

2016-10-15

This paper presents the concept of developing an integrated engineering system for ER to improve efficiency and utilization of engineering system. Each process including computer system and database was introduced separately by each department at that different time. Each engineering process has a close relation with other engineering processes. The introduction of processes in a different time has caused the several problems such as lack of interrelationship between engineering processes, lack of integration fleet-wide statistical data, lack of the function of data comparison among plants and increase of access time by different access location on internet. These problems have caused inefficiency of engineering system utilization to get proper information and degraded engineering system utilization. KHNP has introduced and conducted advanced engineering processes to maintain equipment effectively in a highly reliable condition since 2000s. But engineering systems for process implementation have been developed in each department at a different time. This has caused the problems of process inefficiency and data discordance. Integrated Engineering System(IES) to integrate dispersed engineering processes will improve work efficiency and utilization of engineering system because integration system would enable engineer to get total engineering information easily and do engineering work efficiently.

Integrated dry NO{sub x}/SO{sub 2} emissions control system: integrated system test report

Energy Technology Data Exchange (ETDEWEB)

Smith, R.A.; Muzio, L.J. [Fossil Energy Research Corp., Laguna Hills, CA (United States); Hunt, T. [Public Service Co. of Colorado, Denver, CO (United States)

1997-04-01

The DOE sponsored Integrated Dry NO{sub x}/SO{sub 2} Emissions Control System Program, is a Clean Coal Technology III demonstration, being conducted by Public Service Company of Colorado. The test site is Arapahoe Generating Station Unit 4, a 100 MWe, down-fired utility boiler burning a low-sulfur Western coal. The project goal is to demonstrate up to 70 percent reductions in NO{sub x} and SO{sub 2} emissions through the integration of: (1) down-fired low NO{sub x} burners with overfire air; (2) Selective Non-Catalytic Reduction (SNCR) for additional NO{sub x} removal; and (3) Dry Sorbent Injection (DSI) and duct humidification for SO{sub 2} removal. This report documents the final phase of the test program, in which the overall performance of the integrated system was evaluated. Previous testing has shown that the goal of 70 percent NO{sub x} removal was easily achieved with the combination of low-NO{sub x} burners, overfire air, and urea-based SNCR. Similarly, the ability of the sodium-based DSI system to achieve 70 percent SO{sub 2} removal was also demonstrated previously. The integrated tests demonstrated the synergistic benefit of operating the SNCR and sodium-based DSI systems concurrently. With the automatic control system set to limit the NH{sub 3} emissions to less than 8 ppm, the NO{sub 2} emissions from the sodium-based DSI system were reduced by nominally 50 percent compared to operation with the DSI system alone. Comparably, the combined operation reduced NH{sub 3} emissions, as reflected by a higher urea injection rate for a fixed NH{sub 3} emission limit. With combined DSI and SNCR operation, an ammonia odor problem was encountered around the Unit 4 ash silo (this did not occur with the SNCR system operated alone at comparable NH{sub 3} slip levels). This odor problem is attributed to the sodium changing the rate at which NH{sub 3} is released from the ash when it is wetted for truck transport to the disposal site.

Modeling methodology for supply chain synthesis and disruption analysis

Science.gov (United States)

Wu, Teresa; Blackhurst, Jennifer

2004-11-01

The concept of an integrated or synthesized supply chain is a strategy for managing today's globalized and customer driven supply chains in order to better meet customer demands. Synthesizing individual entities into an integrated supply chain can be a challenging task due to a variety of factors including conflicting objectives, mismatched incentives and constraints of the individual entities. Furthermore, understanding the effects of disruptions occurring at any point in the system is difficult when working toward synthesizing supply chain operations. Therefore, the goal of this research is to present a modeling methodology to manage the synthesis of a supply chain by linking hierarchical levels of the system and to model and analyze disruptions in the integrated supply chain. The contribution of this research is threefold: (1) supply chain systems can be modeled hierarchically (2) the performance of synthesized supply chain system can be evaluated quantitatively (3) reachability analysis is used to evaluate the system performance and verify whether a specific state is reachable, allowing the user to understand the extent of effects of a disruption.

Energy Systems Integration: Demonstrating Distributed Resource Communications

Energy Technology Data Exchange (ETDEWEB)

2017-01-01

Overview fact sheet about the Electric Power Research Institute (EPRI) and Schneider Electric Integrated Network Testbed for Energy Grid Research and Technology Experimentation (INTEGRATE) project at the Energy Systems Integration Facility. INTEGRATE is part of the U.S. Department of Energy's Grid Modernization Initiative.

Establishment of advanced integration technology for site characterization of deep geological repository. Development of information synthesis and interpretation system. Annual report 2007

International Nuclear Information System (INIS)

Osawa, Hideaki; Umeki, Hiroyuki; Ota, Kunio; Maekawa, Keisuke; Kunimaru, Takanori; Niizato, Tadafumi; Asamori, Koichi; Yamanaka, Yoshiaki; Shigehiro, Michiko; Abe, Hironobu; Hama, Katsuhiro; Takeuchi, Shinji; Amano, Kenji; Saegusa, Hiromitsu; Matsukawa, Toshiyuki; Miyamoto, Tetsuo; Toyoda, Gakuji; Sawada, Atsushi; Shimada, Akiomi

2008-11-01

This project is planned as a five-year program aiming to develop an advanced integration technology for characterization of a site for radioactive waste geological disposal. It is carried out by the Geological Isolation Research and Development Directorate of Japan Atomic Energy Agency with the fund of Agency for Natural Resources and Energy of the Ministry of Economy, Trade and Industry. This report summarizes the outcome of the first year (FY 2007) activities of the project. The site characterization is a dynamic and complex process and needs close linkage with repository design and performance assessment (PA). A geosynthesis methodology has been developed for integrating site characterization information into design and PA, and applied for e.g. on-going JAEA's studies at two generic URLs at Mizunami and Horonobe. This methodology explicitly presents an information flow (often referred to as geosynthesis data flow diagram or data flow diagram, in short) from measurements by site investigation to generating data sets for design and PA. It is a useful tool for guiding the site characterization in a transparent and traceable manner. As site investigation proceeds and information being obtained on geological environments of the site increases, the site characterization plan is iteratively reviewed and modified reflecting the updated information. Such modification would also be needed when changes would occur on socio-political boundary conditions. In fact, the data flow diagrams for two generic URL projects have been revised several times so far due to the increase in the amount of information on geological environments and changes of societal conditions. An advanced technology aimed at in this project is therefore focused on developing flexible approach and tools, which is named as Information Synthesis and Interpretation System (ISIS), to support the stepwise 'optimization' of the site characterization plan. In FY 2007, a basic concept for ISIS has been developed

Indirect synthesis of multi-degree of freedom transient systems. [linear programming for a kinematically linear system

Science.gov (United States)

Pilkey, W. D.; Chen, Y. H.

1974-01-01

An indirect synthesis method is used in the efficient optimal design of multi-degree of freedom, multi-design element, nonlinear, transient systems. A limiting performance analysis which requires linear programming for a kinematically linear system is presented. The system is selected using system identification methods such that the designed system responds as closely as possible to the limiting performance. The efficiency is a result of the method avoiding the repetitive systems analyses accompanying other numerical optimization methods.

Accelerator-feasible N-body nonlinear integrable system

Directory of Open Access Journals (Sweden)

V. Danilov

2014-12-01

Full Text Available Nonlinear N-body integrable Hamiltonian systems, where N is an arbitrary number, have attracted the attention of mathematical physicists for the last several decades, following the discovery of some number of these systems. This paper presents a new integrable system, which can be realized in facilities such as particle accelerators. This feature makes it more attractive than many of the previous such systems with singular or unphysical forces.

Multisignal detecting system of pile integrity testing

Science.gov (United States)

Liu, Zuting; Luo, Ying; Yu, Shihai

2002-05-01

The low strain reflection wave method plays a principal rule in the integrating detection of base piles. However, there are some deficiencies with this method. For example, there is a blind area of detection on top of the tested pile; it is difficult to recognize the defects at deep-seated parts of the pile; there is still the planar of 3D domino effect, etc. It is very difficult to solve these problems only with the single-transducer pile integrity testing system. A new multi-signal piles integrity testing system is proposed in this paper, which is able to impulse and collect signals on multiple points on top of the pile. By using the multiple superposition data processing method, the detecting system can effectively restrain the interference and elevate the precision and SNR of pile integrity testing. The system can also be applied to the evaluation of engineering structure health.

Sophistication and integration of plant engineering CAD-CAE systems

International Nuclear Information System (INIS)

Yoshinaga, Toshiaki; Hanyu, Masaharu; Ota, Yoshimi; Kobayashi, Yasuhiro.

1995-01-01

In respective departments in charge of basic planning, design, manufacture, inspection and construction of nuclear power plants, by the positive utilization of CAD/CAE system, efficient workings have been advanced. This time, the plant integrated CAE system wich heightens the function of these individual systems, and can make workings efficient and advanced by unifying and integrating them was developed. This system is composed of the newly developed application system and the data base system which enables the unified management of engineering data and high speed data conversion in addition to the CAD system for three-dimensional plant layout planning. On the basis of the rich experience and the proposal of improvement of designers by the application of the CAD system for three-dimensional plant layout planning to actual machines, the automation, speed increase and the visualization of input and output by graphical user interface (GUI) in the processing of respective applications were made feasible. As the advancement of plant CAE system, scenic engineering system, integrated layout CAE system, electric instrumentation design CAE system and construction planning CAE system are described. As for the integration of plant CAE systems, the integrated engineering data base, the combination of plant CAE systems, and the operation management in the dispersed environment of networks are reported. At present, Hitachi Ltd. exerts efforts for the construction of atomic energy product in formation integrated management system as the second stage of integration. (K.I.)

Integrated inventory information system

Digital Repository Service at National Institute of Oceanography (India)

Sarupria, J.S.; Kunte, P.D.

The nature of oceanographic data and the management of inventory level information are described in Integrated Inventory Information System (IIIS). It is shown how a ROSCOPO (report on observations/samples collected during oceanographic programme...

Advantages and Limitations of Integrated Management System: the Theoretical Viewpoint

Directory of Open Access Journals (Sweden)

Agota Giedrė Raišienė

2013-08-01

Full Text Available Purpose. The goal of the paper is to discuss the potential benefits and to highlight the drawbacks of integrated management system for organizations that seek to improve management process.Methodology. Methods of the research were used: analysis of a scientific and special literature that presents the requirements, models and results of integrated management systems studies, and analysis of statistical data to assess actuality of integrated management systems for enterprises in Lithuania.Findings. Summarizing research findings, it should be stated that the implementation of management system integration should be based on provision of social responsibility and holistic approach to the organization. It requires the long-term united efforts of leaders in a strategic hierarchical level and high organizational maturity to ensure the fluency of the running stages of planning management system integration, preparing documentations, implementing and realizing integrated management system. Also it is necessary to purify the conception of integrated management system in organizational context. Theoretical analysis of integrated management systems show, that all of the management systems can not be well integrated in principle. They can only be partly integrated and coordinated. A need to question the level of integration of management systems is very important as in scientific discourse as in practice. It is important to mark, that the number of organizations, that seek to optimize management processes by implementing the integrated management systems is rapidly increasing in Lithuania, too. It shows that benefit associated with integration of management systems is apprehensible in Lithuania. Advantages of integrated management systems can certainly become even stronger if scientists and practicians join their forces in search of methods of organizational management development.Research limitations. The research limitations related to a lack of

Electronic Integrated Disease Surveillance System and Pathogen Asset Control System

Directory of Open Access Journals (Sweden)

Tom G. Wahl

2012-06-01

Full Text Available Electronic Integrated Disease Surveillance System (EIDSS has been used to strengthen and support monitoring and prevention of dangerous diseases within One Health concept by integrating veterinary and human surveillance, passive and active approaches, case-based records including disease-specific clinical data based on standardised case definitions and aggregated data, laboratory data including sample tracking linked to each case and event with test results and epidemiological investigations. Information was collected and shared in secure way by different means: through the distributed nodes which are continuously synchronised amongst each other, through the web service, through the handheld devices. Electronic Integrated Disease Surveillance System provided near real time information flow that has been then disseminated to the appropriate organisations in a timely manner. It has been used for comprehensive analysis and visualisation capabilities including real time mapping of case events as these unfold enhancing decision making. Electronic Integrated Disease Surveillance System facilitated countries to comply with the IHR 2005 requirements through a data transfer module reporting diseases electronically to the World Health Organisation (WHO data center as well as establish authorised data exchange with other electronic system using Open Architecture approach. Pathogen Asset Control System (PACS has been used for accounting, management and control of biological agent stocks. Information on samples and strains of any kind throughout their entire lifecycle has been tracked in a comprehensive and flexible solution PACS. Both systems have been used in a combination and individually. Electronic Integrated Disease Surveillance System and PACS are currently deployed in the Republics of Kazakhstan, Georgia and Azerbaijan as a part of the Cooperative Biological Engagement Program (CBEP sponsored by the US Defense Threat Reduction Agency (DTRA.

Electronic integrated disease surveillance system and pathogen asset control system.

Science.gov (United States)

Wahl, Tom G; Burdakov, Aleksey V; Oukharov, Andrey O; Zhilokov, Azamat K

2012-06-20

Electronic Integrated Disease Surveillance System (EIDSS) has been used to strengthen and support monitoring and prevention of dangerous diseases within One Health concept by integrating veterinary and human surveillance, passive and active approaches, case-based records including disease-specific clinical data based on standardised case definitions and aggregated data, laboratory data including sample tracking linked to each case and event with test results and epidemiological investigations. Information was collected and shared in secure way by different means: through the distributed nodes which are continuously synchronised amongst each other, through the web service, through the handheld devices. Electronic Integrated Disease Surveillance System provided near real time information flow that has been then disseminated to the appropriate organisations in a timely manner. It has been used for comprehensive analysis and visualisation capabilities including real time mapping of case events as these unfold enhancing decision making. Electronic Integrated Disease Surveillance System facilitated countries to comply with the IHR 2005 requirements through a data transfer module reporting diseases electronically to the World Health Organisation (WHO) data center as well as establish authorised data exchange with other electronic system using Open Architecture approach. Pathogen Asset Control System (PACS) has been used for accounting, management and control of biological agent stocks. Information on samples and strains of any kind throughout their entire lifecycle has been tracked in a comprehensive and flexible solution PACS.Both systems have been used in a combination and individually. Electronic Integrated Disease Surveillance System and PACS are currently deployed in the Republics of Kazakhstan, Georgia and Azerbaijan as a part of the Cooperative Biological Engagement Program (CBEP) sponsored by the US Defense Threat Reduction Agency (DTRA).

Analysis of integrated energy systems

International Nuclear Information System (INIS)

Matsuhashi, Takaharu; Kaya, Yoichi; Komiyama, Hiroshi; Hayashi, Taketo; Yasukawa, Shigeru.

1988-01-01

World attention is now attracted to the concept of Novel Horizontally Integrated Energy System (NHIES). In NHIES, all fossil fuels are fist converted into CO and H 2 . Potential environmental contaminants such as sulfur are removed during this process. CO turbines are mainly used to generate electric power. Combustion is performed in pure oxygen produced through air separation, making it possible to completely prevent the formation of thermal NOx. Thus, NHIES would release very little amount of such substances that would contribute to acid rain. In this system, the intermediate energy sources of CO, H 2 and O 2 are integrated horizontally. They are combined appropriately to produce a specific form of final energy source. The integration of intermediate energy sources can provide a wide variety of final energy sources, allowing any type of fossil fuel to serve as an alternative to other types of fossil fuel. Another feature of NHIES is the positive use of nuclear fuel to reduce the formation of CO 2 . Studies are under way in Japan to develop a new concept of integrated energy system. These studies are especially aimed at decreased overall efficiency and introduction of new liquid fuels that are high in conversion efficiency. Considerations are made on the final form of energy source, robust control, acid fallout, and CO 2 reduction. (Nogami, K.)

Development of an automated modular system for the synthesis of [11C]acetate.

Science.gov (United States)

Felicini, Chiara; Någren, Kjell; Berton, Andrea; Pascali, Giancarlo; Salvadori, Piero Alberto

2010-12-01

Carboxylation reactions offer a straightforward method for the synthesis of carbon-11 labelled carboxylic acids. Among these, the preparation of carbon-11 (C)-acetate is receiving increasing attention because of diagnostic applications in oncology in addition to its well-established use as a probe for myocardial oxidative metabolism. Although a number of dedicated modules are commercially available, the development of the synthesis on flexible platforms would be beneficial to widen the number of tracers, in particular for preclinical assessment and testing. In this study, the carboxylation reaction was implemented for the synthesis of sodium 1-[C]acetate after the classic route of carboxylation of methylmagnesium chloride by [C]carbon dioxide, followed by the acidic hydrolysis, purification and sterile filtration. This was performed using a commercially available kit of preassembled hardware units and fully compatible components of radiochemistry automation (VarioSystem). The system proved be to highly versatile and inexpensive and allowed a quick translation of the radiochemistry project into a working system even by less experienced personnel, because of predefined interfaces between electronic parts and operating software (preloaded on a laptop and included in the kit). The automatic module proved to be a simple and reliable system for the production of 1-[C]acetate that was prepared in 24 min (total synthesis time) with stable radiochemical yields (20% nondecay corrected) and high radiochemical purity (>97%). The module is used routinely to produce 1-[C]acetate for preclinical studies and is being implemented for the production of the labelled fatty acids.

Note on integrability of certain homogeneous Hamiltonian systems

Energy Technology Data Exchange (ETDEWEB)

Szumiński, Wojciech [Institute of Physics, University of Zielona Góra, Licealna 9, PL-65-407, Zielona Góra (Poland); Maciejewski, Andrzej J. [Institute of Astronomy, University of Zielona Góra, Licealna 9, PL-65-407, Zielona Góra (Poland); Przybylska, Maria, E-mail: M.Przybylska@if.uz.zgora.pl [Institute of Physics, University of Zielona Góra, Licealna 9, PL-65-407, Zielona Góra (Poland)

2015-12-04

In this paper we investigate a class of natural Hamiltonian systems with two degrees of freedom. The kinetic energy depends on coordinates but the system is homogeneous. Thanks to this property it admits, in a general case, a particular solution. Using this solution we derive necessary conditions for the integrability of such systems investigating differential Galois group of variational equations. - Highlights: • Necessary integrability conditions for some 2D homogeneous Hamilton systems are given. • Conditions are obtained analysing differential Galois group of variational equations. • New integrable and superintegrable systems are identified.

Coal Integrated Gasification Fuel Cell System Study

Energy Technology Data Exchange (ETDEWEB)

Gregory Wotzak; Chellappa Balan; Faress Rahman; Nguyen Minh

2003-08-01

The pre-baseline configuration for an Integrated Gasification Fuel Cell (IGFC) system has been developed. This case uses current gasification, clean-up, gas turbine, and bottoming cycle technologies together with projected large planar Solid Oxide Fuel Cell (SOFC) technology. This pre-baseline case will be used as a basis for identifying the critical factors impacting system performance and the major technical challenges in implementing such systems. Top-level system requirements were used as the criteria to evaluate and down select alternative sub-systems. The top choice subsystems were subsequently integrated to form the pre-baseline case. The down-selected pre-baseline case includes a British Gas Lurgi (BGL) gasification and cleanup sub-system integrated with a GE Power Systems 6FA+e gas turbine and the Hybrid Power Generation Systems planar Solid Oxide Fuel Cell (SOFC) sub-system. The overall efficiency of this system is estimated to be 43.0%. The system efficiency of the pre-baseline system provides a benchmark level for further optimization efforts in this program.

Advantages and Limitations of Integrated Management System: the Theoretical Viewpoint

Directory of Open Access Journals (Sweden)

Agota Giedrė Raišienė

2011-08-01

Full Text Available Purpose. The goal of the paper is to discuss the potential benefits and to highlight the drawbacks of integrated management system for organizations that seek to improve management process.Methodology. Methods of the research were used: analysis of a scientific and special literature that presents the requirements, models and results of integrated management systems studies, and analysis of statistical data to assess actuality of integrated management systems for enterprises in Lithuania.Findings. Summarizing research findings, it should be stated that the implementation of management system integration should be based on provision of social responsibility and holistic approach to the organization. It requires the long-term united efforts of leaders in a strategic hierarchical level and high organizational maturity to ensure the fluency of the running stages of planning management system integration, preparing documentations, implementing and realizing integrated management system. Also it is necessary to purify the conception of integrated management system in organizational context. Theoretical analysis of integrated management systems show, that all of the management systems can not be well integrated in principle. They can only be partly integrated and coordinated. A need to question the level of integration of managementsystems is very important as in scientific discourse as in practice. It is important to mark, that the number of organizations, that seek to optimize management processes by implementing the integrated management systems is rapidly increasing in Lithuania, too. It shows that benefit associated with integration of management systems is apprehensible in Lithuania. Advantages of integrated management systems can certainly become even stronger if scientists and practicians join their forces in search of methods of organizational management development.Research limitations. The research limitations related to a lack of integrated

Integrated ADIOS-IGENPRO operator advisory support system

International Nuclear Information System (INIS)

Lee, Dong Young; Park, J. H.; Kim, J. T.; Kim, C. H.; Park, W. M.; Hwang, I. K.; Cheon, S. W.; Song, S. J.

2001-05-01

The I and C systems and control rooms of nuclear power plants have been constructed by using the automatic control concept and changed to computer-based systems in nowadays. For Increase of an automation and CRT, the role of operators is changed to monitor the condition of the nuclear power plants. Therefore, the information that is offered to operators has to integrate in order for operator to understand the hole condition of plants. In commercial nuclear plants, raw data of sensors and components are shown in a control room. So, operators can not diagnose the condition of plants correctly. For a development of an integrated operator aid system which contain an alarm processing system and a fault diagnosis system, we integrated IGENPRO of ANL(Argonne National Lab.) and ADIOS of KAERI (Korea Atomic Energy Institute). IGENPRO is a fault diagnosis system contains three module such as PROTREN, PRODIAG and PROTREN. ADIOS is an alarm processing system that informs operators of important alarms. The integrated operator advisory support system developed in the research is composed of an alarm processing module and a fault diagnosis module. The alarm processing module shows important alarms to operator by using dynamic alarm filtering methods. The fault diagnosis module shows the cause of faults of sensors and hardwares

Integrated ADIOS-IGENPRO operator advisory support system

Energy Technology Data Exchange (ETDEWEB)

Lee, Dong Young; Park, J. H.; Kim, J. T.; Kim, C. H.; Park, W. M.; Hwang, I. K.; Cheon, S. W.; Song, S. J

2001-05-01

The I and C systems and control rooms of nuclear power plants have been constructed by using the automatic control concept and changed to computer-based systems in nowadays. For Increase of an automation and CRT, the role of operators is changed to monitor the condition of the nuclear power plants. Therefore, the information that is offered to operators has to integrate in order for operator to understand the hole condition of plants. In commercial nuclear plants, raw data of sensors and components are shown in a control room. So, operators can not diagnose the condition of plants correctly. For a development of an integrated operator aid system which contain an alarm processing system and a fault diagnosis system, we integrated IGENPRO of ANL(Argonne National Lab.) and ADIOS of KAERI (Korea Atomic Energy Institute). IGENPRO is a fault diagnosis system contains three module such as PROTREN, PRODIAG and PROTREN. ADIOS is an alarm processing system that informs operators of important alarms. The integrated operator advisory support system developed in the research is composed of an alarm processing module and a fault diagnosis module. The alarm processing module shows important alarms to operator by using dynamic alarm filtering methods. The fault diagnosis module shows the cause of faults of sensors and hardwares.

An architecture for robotic system integration

International Nuclear Information System (INIS)

Butler, P.L.; Reister, D.B.; Gourley, C.S.; Thayer, S.M.

1993-01-01

An architecture has been developed to provide an object-oriented framework for the integration of multiple robotic subsystems into a single integrated system. By using an object-oriented approach, all subsystems can interface with each other, and still be able to be customized for specific subsystem interface needs. The object-oriented framework allows the communications between subsystems to be hidden from the interface specification itself. Thus, system designers can concentrate on what the subsystems are to do, not how to communicate. This system has been developed for the Environmental Restoration and Waste Management Decontamination and Decommissioning Project at Oak Ridge National Laboratory. In this system, multiple subsystems are defined to separate the functional units of the integrated system. For example, a Human-Machine Interface (HMI) subsystem handles the high-level machine coordination and subsystem status display. The HMI also provides status-logging facilities and safety facilities for use by the remaining subsystems. Other subsystems have been developed to provide specific functionality, and many of these can be reused by other projects

HDR video synthesis for vision systems in dynamic scenes

Science.gov (United States)

Shopovska, Ivana; Jovanov, Ljubomir; Goossens, Bart; Philips, Wilfried

2016-09-01

High dynamic range (HDR) image generation from a number of differently exposed low dynamic range (LDR) images has been extensively explored in the past few decades, and as a result of these efforts a large number of HDR synthesis methods have been proposed. Since HDR images are synthesized by combining well-exposed regions of the input images, one of the main challenges is dealing with camera or object motion. In this paper we propose a method for the synthesis of HDR video from a single camera using multiple, differently exposed video frames, with circularly alternating exposure times. One of the potential applications of the system is in driver assistance systems and autonomous vehicles, involving significant camera and object movement, non- uniform and temporally varying illumination, and the requirement of real-time performance. To achieve these goals simultaneously, we propose a HDR synthesis approach based on weighted averaging of aligned radiance maps. The computational complexity of high-quality optical flow methods for motion compensation is still pro- hibitively high for real-time applications. Instead, we rely on more efficient global projective transformations to solve camera movement, while moving objects are detected by thresholding the differences between the trans- formed and brightness adapted images in the set. To attain temporal consistency of the camera motion in the consecutive HDR frames, the parameters of the perspective transformation are stabilized over time by means of computationally efficient temporal filtering. We evaluated our results on several reference HDR videos, on synthetic scenes, and using 14-bit raw images taken with a standard camera.

Automating multistep flow synthesis: approach and challenges in integrating chemistry, machines and logic

Directory of Open Access Journals (Sweden)

Chinmay A. Shukla

2017-05-01

Full Text Available The implementation of automation in the multistep flow synthesis is essential for transforming laboratory-scale chemistry into a reliable industrial process. In this review, we briefly introduce the role of automation based on its application in synthesis viz. auto sampling and inline monitoring, optimization and process control. Subsequently, we have critically reviewed a few multistep flow synthesis and suggested a possible control strategy to be implemented so that it helps to reliably transfer the laboratory-scale synthesis strategy to a pilot scale at its optimum conditions. Due to the vast literature in multistep synthesis, we have classified the literature and have identified the case studies based on few criteria viz. type of reaction, heating methods, processes involving in-line separation units, telescopic synthesis, processes involving in-line quenching and process with the smallest time scale of operation. This classification will cover the broader range in the multistep synthesis literature.

Advanced optical manufacturing digital integrated system

Science.gov (United States)

Tao, Yizheng; Li, Xinglan; Li, Wei; Tang, Dingyong

2012-10-01

It is necessarily to adapt development of advanced optical manufacturing technology with modern science technology development. To solved these problems which low of ration, ratio of finished product, repetition, consistent in big size and high precision in advanced optical component manufacturing. Applied business driven and method of Rational Unified Process, this paper has researched advanced optical manufacturing process flow, requirement of Advanced Optical Manufacturing integrated System, and put forward architecture and key technology of it. Designed Optical component core and Manufacturing process driven of Advanced Optical Manufacturing Digital Integrated System. the result displayed effective well, realized dynamic planning Manufacturing process, information integration improved ratio of production manufactory.

Integrated waste and water management system

Science.gov (United States)

Murray, R. W.; Sauer, R. L.

1986-01-01

The performance requirements of the NASA Space Station have prompted a reexamination of a previously developed integrated waste and water management system that used distillation and catalytic oxydation to purify waste water, and microbial digestion and incineration for waste solids disposal. This system successfully operated continuously for 206 days, for a 4-man equivalent load of urine, feces, wash water, condensate, and trash. Attention is given to synergisms that could be established with other life support systems, in the cases of thermal integration, design commonality, and novel technologies.

Indonesian Text-To-Speech System Using Diphone Concatenative Synthesis

Directory of Open Access Journals (Sweden)

Sutarman

2015-02-01

Full Text Available In this paper, we describe the design and develop a database of Indonesian diphone synthesis using speech segment of recorded voice to be converted from text to speech and save it as audio file like WAV or MP3. In designing and develop a database of Indonesian diphone there are several steps to follow; First, developed Diphone database includes: create a list of sample of words consisting of diphones organized by prioritizing looking diphone located in the middle of a word if not at the beginning or end; recording the samples of words by segmentation. ;create diphones made with a tool Diphone Studio 1.3. Second, develop system using Microsoft Visual Delphi 6.0, includes: the conversion system from the input of numbers, acronyms, words, and sentences into representations diphone. There are two kinds of conversion (process alleged in analyzing the Indonesian text-to-speech system. One is to convert the text to be sounded to phonem and two, to convert the phonem to speech. Method used in this research is called Diphone Concatenative synthesis, in which recorded sound segments are collected. Every segment consists of a diphone (2 phonems. This synthesizer may produce voice with high level of naturalness. The Indonesian Text to Speech system can differentiate special phonemes like in ‘Beda’ and ‘Bedak’ but sample of other spesific words is necessary to put into the system. This Indonesia TTS system can handle texts with abbreviation, there is the facility to add such words.

Web-Mediated Knowledge Synthesis for Educators

Science.gov (United States)

DeSchryver, Michael

2015-01-01

Ubiquitous and instant access to information on the Web is challenging what constitutes 21st century literacies. This article explores the notion of Web-mediated knowledge synthesis, an approach to integrating Web-based learning that may result in generative synthesis of ideas. This article describes the skills and strategies that may support…

Integrated Computer System of Management in Logistics

Science.gov (United States)

Chwesiuk, Krzysztof

2011-06-01

This paper aims at presenting a concept of an integrated computer system of management in logistics, particularly in supply and distribution chains. Consequently, the paper includes the basic idea of the concept of computer-based management in logistics and components of the system, such as CAM and CIM systems in production processes, and management systems for storage, materials flow, and for managing transport, forwarding and logistics companies. The platform which integrates computer-aided management systems is that of electronic data interchange.

Integrated management systems in the nuclear field

International Nuclear Information System (INIS)

Beckmerhagen, I.A.; Berg, H.P.; Karapetrovic, S.V.; Willborn, W.O.

2005-01-01

In the last years several internationally accepted standards such as the ISO 9000 and ISO 14000 series and other function-specific management systems standards have been developed. At the same time, it has become imperative for organisations to continuously improve their overall quality, environmental and safety performance. Therefore, the need to create integrated management systems is of growing importance to enable an easier handling of the different management systems. This paper has two main objectives. The first one is to address the key issues in the underlying theory of integrated management systems including benefits and limits, the second one is to illustrate the importance of an integrated (in particular safety) management system and the experience feedback providing examples from different areas and different organisations in the nuclear field. (orig.)

National Ignition Facility sub-system design requirements integrated timing system SSDR 1.5.3

International Nuclear Information System (INIS)

Wiedwald, J.; Van Aersau, P.; Bliss, E.

1996-01-01

This System Design Requirement document establishes the performance, design, development, and test requirements for the Integrated Timing System, WBS 1.5.3 which is part of the NIF Integrated Computer Control System (ICCS). The Integrated Timing System provides all temporally-critical hardware triggers to components and equipment in other NIF systems

Integration of process computer systems to Cofrentes NPP

International Nuclear Information System (INIS)

Saettone Justo, A.; Pindado Andres, R.; Buedo Jimenez, J.L.; Jimenez Fernandez-Sesma, A.; Delgado Muelas, J.A.

1997-01-01

The existence of three different process computer systems in Cofrentes NPP and the ageing of two of them have led to the need for their integration into a single real time computer system, known as Integrated ERIS-Computer System (SIEC), which covers the functionality of the three systems: Process Computer (PC), Emergency Response Information System (ERIS) and Nuclear Calculation Computer (OCN). The paper describes the integration project developed, which has essentially consisted in the integration of PC, ERIS and OCN databases into a single database, the migration of programs from the old process computer into the new SIEC hardware-software platform and the installation of a communications programme to transmit all necessary data for OCN programs from the SIEC computer, which in the new configuration is responsible for managing the databases of the whole system. (Author)

Legacy system integration using web technology

Science.gov (United States)

Kennedy, Richard L.; Seibert, James A.; Hughes, Chris J.

2000-05-01

As healthcare moves towards a completely digital, multimedia environment there is an opportunity to provide for cost- effective, highly distributed physician access to clinical information including radiology-based imaging. In order to address this opportunity a Universal Clinical Desktop (UCD) system was developed. A UCD provides a single point of entry into an integrated view of all types of clinical data available within a network of disparate healthcare information systems. In order to explore the application of a UCD in a hospital environment, a pilot study was established with the University of California Davis Medical Center using technology from Trilix Information Systems. Within this pilot environment the information systems integrated under the UCD include a radiology information system (RIS), a picture archive and communication system (PACS) and a laboratory information system (LIS).

Human Systems Integration Synthesis Model for Ship Design

Science.gov (United States)

2012-09-01

33  b.   Diesel .......................................................................................35  c.  Gas Turbine ...acquire systems capable of maximizing the output of the Navy’s Human Capital. The term Human Capital is defined by Kaplan and Norton (2004, p. 13) as...Machine—engines: steam, diesel, gas turbine , or nuclear Prior to establishing a ship’s speed requirements, one must understand the forces that

Evaluation of exercise-respiratory system modifications and integration schemes for physiological systems

Science.gov (United States)

Gallagher, R. R.

1974-01-01

Exercise subroutine modifications are implemented in an exercise-respiratory system model yielding improvement of system response to exercise forcings. A more physiologically desirable respiratory ventilation rate in addition to an improved regulation of arterial gas tensions and cerebral blood flow is observed. A respiratory frequency expression is proposed which would be appropriate as an interfacing element of the respiratory-pulsatile cardiovascular system. Presentation of a circulatory-respiratory system integration scheme along with its computer program listing is given. The integrated system responds to exercise stimulation for both nonstressed and stressed physiological states. Other integration possibilities are discussed with respect to the respiratory, pulsatile cardiovascular, thermoregulatory, and the long-term circulatory systems.

A study on infinite number of integrals of motion in classically integrable system with boundary: Pt.1

International Nuclear Information System (INIS)

Chen Yixin; Luo Xudong

1998-01-01

By the zero curvature condition in classically integrable system, the generating functions for integrals of motion and equations for solving K +- matrices are obtained in two-dimensional integrable systems on a finite interval with independent boundary conditions on each end. Classically integrable boundary conditions will be found by solving K +- matrices. The authors develop a Hamiltonian method in classically integrable system with independent boundary conditions on each end. The result can be applied to more integrable systems than those associated with E.K. Sklyanin's approach

Human Systems Integration in Practice: Constellation Lessons Learned

Science.gov (United States)

Zumbado, Jennifer Rochlis

2012-01-01

NASA's Constellation program provided a unique testbed for Human Systems Integration (HSI) as a fundamental element of the Systems Engineering process. Constellation was the first major program to have HSI mandated by NASA's Human Rating document. Proper HSI is critical to the success of any project that relies on humans to function as operators, maintainers, or controllers of a system. HSI improves mission, system and human performance, significantly reduces lifecycle costs, lowers risk and minimizes re-design. Successful HSI begins with sufficient project schedule dedicated to the generation of human systems requirements, but is by no means solely a requirements management process. A top-down systems engineering process that recognizes throughout the organization, human factors as a technical discipline equal to traditional engineering disciplines with authority for the overall system. This partners with a bottoms-up mechanism for human-centered design and technical issue resolution. The Constellation Human Systems Integration Group (HSIG) was a part of the Systems Engineering and Integration (SE&I) organization within the program office, and existed alongside similar groups such as Flight Performance, Environments & Constraints, and Integrated Loads, Structures and Mechanisms. While the HSIG successfully managed, via influence leadership, a down-and-in Community of Practice to facilitate technical integration and issue resolution, it lacked parallel top-down authority to drive integrated design. This presentation will discuss how HSI was applied to Constellation, the lessons learned and best practices it revealed, and recommendations to future NASA program and project managers. This presentation will discuss how Human Systems Integration (HSI) was applied to NASA's Constellation program, the lessons learned and best practices it revealed, and recommendations to future NASA program and project managers on how to accomplish this critical function.

Boolean integration. [applied to switching network synthesis

Science.gov (United States)

Tucker, J. H.; Tapia, M. A.; Bennett, A. W.

1976-01-01

This paper presents the necessary and sufficient conditions for a given differential expression to be compatibly integrable and it presents the necessary and sufficient conditions for a given expression to be exactly integrable. Methods are given for integrating a differential expression when it is exactly integrable and when it is compatibly integrable. The physical interpretation is given of the integral of order k, of a differential expression, and it is shown that any differential expression of the proper form is integrable by parts.

Controller synthesis for negative imaginary systems: a data driven approach

KAUST Repository

Mabrok, Mohamed

2016-02-17

The negative imaginary (NI) property occurs in many important applications. For instance, flexible structure systems with collocated force actuators and position sensors can be modelled as negative imaginary systems. In this study, a data-driven controller synthesis methodology for NI systems is presented. In this approach, measured frequency response data of the plant is used to construct the controller frequency response at every frequency by minimising a cost function. Then, this controller response is used to identify the controller transfer function using system identification methods. © The Institution of Engineering and Technology 2016.

A secure and synthesis tele-ophthalmology system.

Science.gov (United States)

Wei, Zhuo; Wu, Yongdong; Deng, Robert H; Yu, Shengsheng; Yao, Haixia; Zhao, Zhigang; Ngoh, Lek Heng; Han, Lim Tock; Poh, Eugenie W T

2008-10-01

This paper describes a secure and synthesis ophthalmology telemedicine system, referred to as TeleOph. Under a Secure Socket Layer (SSL) channel, patient prerecorded data can be safely transferred via the Internet. With encrypted videoconference and white-board, the system not only supports hospital-to-clinic consultation, but also supplies hospital-tohospital joint discussion. Based on Directshow technology (Microsoft Corporation, Redmond, WA), video cameras connected to the computer by firewire can be captured and controlled to sample video data. By using TWAIN technology, the system automatically identifies networked still cameras (on fundus and slitlamp devices) and retrieves images. All the images are stored in a selected format (such as JPEG, DICOM, BMP). Besides offline-transferring prerecorded data, the system also supplies online sampling of patient data (real-time capturing from remote places). The system was deployed at Tan Tock Seng Hospital, Singapore and Ang Mo Kio, Singapore, where 100 patients were enrolled in the system for examination. TeleOph can be successfully used for patient consultation, and hospital joint discussion. Meanwhile, TeleOph can supply both offline and online sampling of patient data.

Sustainable Chemical Process Development through an Integrated Framework

DEFF Research Database (Denmark)

Papadakis, Emmanouil; Kumar Tula, Anjan; Anantpinijwatna, Amata

2016-01-01

This paper describes the development and the application of a general integrated framework based on systematic model-based methods and computer-aided tools with the objective to achieve more sustainable process designs and to improve the process understanding. The developed framework can be appli...... studies involve multiphase reaction systems for the synthesis of active pharmaceutical ingredients....

Sandia National Laboratories: Integrated Military Systems

Science.gov (United States)

Defense Systems & Assessments About Defense Systems & Assessments Program Areas Accomplishments Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios ; Culture Work-Life Balance Special Programs Integrated Military Systems (IMS) Capabilities Facilities

Extending and expanding the Darwinian synthesis: the role of complex systems dynamics.

Science.gov (United States)

Weber, Bruce H

2011-03-01

Darwinism is defined here as an evolving research tradition based upon the concepts of natural selection acting upon heritable variation articulated via background assumptions about systems dynamics. Darwin's theory of evolution was developed within a context of the background assumptions of Newtonian systems dynamics. The Modern Evolutionary Synthesis, or neo-Darwinism, successfully joined Darwinian selection and Mendelian genetics by developing population genetics informed by background assumptions of Boltzmannian systems dynamics. Currently the Darwinian Research Tradition is changing as it incorporates new information and ideas from molecular biology, paleontology, developmental biology, and systems ecology. This putative expanded and extended synthesis is most perspicuously deployed using background assumptions from complex systems dynamics. Such attempts seek to not only broaden the range of phenomena encompassed by the Darwinian Research Tradition, such as neutral molecular evolution, punctuated equilibrium, as well as developmental biology, and systems ecology more generally, but to also address issues of the emergence of evolutionary novelties as well as of life itself. Copyright © 2010 Elsevier Ltd. All rights reserved.

Information Security Management - Part Of The Integrated Management System

Science.gov (United States)

Manea, Constantin Adrian

2015-07-01

The international management standards allow their integrated approach, thereby combining aspects of particular importance to the activity of any organization, from the quality management systems or the environmental management of the information security systems or the business continuity management systems. Although there is no national or international regulation, nor a defined standard for the Integrated Management System, the need to implement an integrated system occurs within the organization, which feels the opportunity to integrate the management components into a cohesive system, in agreement with the purpose and mission publicly stated. The issues relating to information security in the organization, from the perspective of the management system, raise serious questions to any organization in the current context of electronic information, reason for which we consider not only appropriate but necessary to promote and implement an Integrated Management System Quality - Environment - Health and Operational Security - Information Security

CIPSS [computer-integrated process and safeguards system]: The integration of computer-integrated manufacturing and robotics with safeguards, security, and process operations

International Nuclear Information System (INIS)

Leonard, R.S.; Evans, J.C.

1987-01-01

This poster session describes the computer-integrated process and safeguards system (CIPSS). The CIPSS combines systems developed for factory automation and automated mechanical functions (robots) with varying degrees of intelligence (expert systems) to create an integrated system that would satisfy current and emerging security and safeguards requirements. Specifically, CIPSS is an extension of the automated physical security functions concepts. The CIPSS also incorporates the concepts of computer-integrated manufacturing (CIM) with integrated safeguards concepts, and draws upon the Defense Advance Research Project Agency's (DARPA's) strategic computing program

Intelligent Integrated Health Management for a System of Systems

Science.gov (United States)

Smith, Harvey; Schmalzel, John; Figueroa, Fernando

2008-01-01

An intelligent integrated health management system (IIHMS) incorporates major improvements over prior such systems. The particular IIHMS is implemented for any system defined as a hierarchical distributed network of intelligent elements (HDNIE), comprising primarily: (1) an architecture (Figure 1), (2) intelligent elements, (3) a conceptual framework and taxonomy (Figure 2), and (4) and ontology that defines standards and protocols. Some definitions of terms are prerequisite to a further brief description of this innovation: A system-of-systems (SoS) is an engineering system that comprises multiple subsystems (e.g., a system of multiple possibly interacting flow subsystems that include pumps, valves, tanks, ducts, sensors, and the like); 'Intelligent' is used here in the sense of artificial intelligence. An intelligent element may be physical or virtual, it is network enabled, and it is able to manage data, information, and knowledge (DIaK) focused on determining its condition in the context of the entire SoS; As used here, 'health' signifies the functionality and/or structural integrity of an engineering system, subsystem, or process (leading to determination of the health of components); 'Process' can signify either a physical process in the usual sense of the word or an element into which functionally related sensors are grouped; 'Element' can signify a component (e.g., an actuator, a valve), a process, a controller, an actuator, a subsystem, or a system; The term Integrated System Health Management (ISHM) is used to describe a capability that focuses on determining the condition (health) of every element in a complex system (detect anomalies, diagnose causes, prognosis of future anomalies), and provide data, information, and knowledge (DIaK) not just data to control systems for safe and effective operation. A major novel aspect of the present development is the concept of intelligent integration. The purpose of intelligent integration, as defined and

Minimum energy consumption process synthesis for energy saving

Energy Technology Data Exchange (ETDEWEB)

Xiao-Ping, Jia [Institute for Petroleum and Chemical Industry, Qingdao University of Science and Technology, Qingdao 266042, Shandong (China); Department of Environmental Science and Engineering, Tsinghua University, Beijing 100084 (China); Fang, Wang; Shu-Guang, Xiang; Xin-Sun, Tan; Fang-Yu, Han [Institute for Petroleum and Chemical Industry, Qingdao University of Science and Technology, Qingdao 266042, Shandong (China)

2008-05-15

The paper presents a synthesis strategy for the chemical processes with energy saving. The concept of minimum energy consumption process (MECP) is proposed. Three characteristics of MECP are introduced, including thermodynamic minimum energy demand, energy consumption efficiency and integration degree. These characteristics are evaluated according to quantitative thermodynamic analysis and qualitative knowledge rules. The procedure of synthesis strategy is proposed to support the generation of MECP alternatives, which combine flowsheet integration and heat integration. The cases studies will focus on how integration degrees of a process affect the energy-saving results. The separation sequences of the hydrodealkylation of toluene (HDA) process and ethanol distillation process as case studies are used to illustrate. (author)

Heat Integration of the Water-Gas Shift Reaction System for Carbon Sequestration Ready IGCC Process with Chemical Looping

Energy Technology Data Exchange (ETDEWEB)

Juan M. Salazara; Stephen E. Zitney; Urmila M. Diwekara

2010-01-01

Integrated gasification combined cycle (IGCC) technology has been considered as an important alternative for efficient power systems that can reduce fuel consumption and CO2 emissions. One of the technological schemes combines water-gas shift reaction and chemical-looping combustion as post gasification techniques in order to produce sequestration-ready CO2 and potentially reduce the size of the gas turbine. However, these schemes have not been energetically integrated and process synthesis techniques can be applied to obtain an optimal flowsheet. This work studies the heat exchange network synthesis (HENS) for the water-gas shift reaction train employing a set of alternative designs provided by Aspen energy analyzer (AEA) and combined in a process superstructure that was simulated in Aspen Plus (AP). This approach allows a rigorous evaluation of the alternative designs and their combinations avoiding all the AEA simplifications (linearized models of heat exchangers). A CAPE-OPEN compliant capability which makes use of a MINLP algorithm for sequential modular simulators was employed to obtain a heat exchange network that provided a cost of energy that was 27% lower than the base case. Highly influential parameters for the pos gasification technologies (i.e. CO/steam ratio, gasifier temperature and pressure) were calculated to obtain the minimum cost of energy while chemical looping parameters (oxidation and reduction temperature) were ensured to be satisfied.

Design of distributed systems of hydrolithosphere processes management. A synthesis of distributed management systems

Science.gov (United States)

Pershin, I. M.; Pervukhin, D. A.; Ilyushin, Y. V.; Afanaseva, O. V.

2017-10-01

The paper considers an important problem of designing distributed systems of hydrolithosphere processes management. The control actions on the hydrolithosphere processes under consideration are implemented by a set of extractive wells. The article shows the method of defining the approximation links for description of the dynamic characteristics of hydrolithosphere processes. The structure of distributed regulators, used in the management systems by the considered processes, is presented. The paper analyses the results of the synthesis of the distributed management system and the results of modelling the closed-loop control system by the parameters of the hydrolithosphere process.

Plant-wide integrated equipment monitoring and analysis system

International Nuclear Information System (INIS)

Morimoto, C.N.; Hunter, T.A.; Chiang, S.C.

2004-01-01

A nuclear power plant equipment monitoring system monitors plant equipment and reports deteriorating equipment conditions. The more advanced equipment monitoring systems can also provide information for understanding the symptoms and diagnosing the root cause of a problem. Maximizing the equipment availability and minimizing or eliminating consequential damages are the ultimate goals of equipment monitoring systems. GE Integrated Equipment Monitoring System (GEIEMS) is designed as an integrated intelligent monitoring and analysis system for plant-wide application for BWR plants. This approach reduces system maintenance efforts and equipment monitoring costs and provides information for integrated planning. This paper describes GEIEMS and how the current system is being upgraded to meet General Electric's vision for plant-wide decision support. (author)

Implementation of an integrated on-line process surveillance and diagnostic system at the Halden reactor project: MOAS

International Nuclear Information System (INIS)

Kim, I.S.; Grini, R.-E.; Nilsen, S.

2001-01-01

MOAS is an integrated on-line process surveillance and diagnostic system that uses several different models for knowledge acquisition and diagnostic reasoning, such as goal-tree success-tree model, process monitor trees, and sensor failure diagnosis trees. Within these models, the knowledge of the process and its operation, including deep knowledge, like mass balance or controller algorithm, is incorporated. During an extensive review, made as part of the integrated diagnosis system project of the Halden reactor project, MOAS (Maryland Operator Advisory System) was identified as one of the most thorough systems developed thus far. MOAS encompasses diverse functional aspects that are required for an effective process disturbance management: (1) intelligent process monitoring and alarming, (2) on-line sensor data validation and sensor failure diagnosis, (3) on-line hardware (besides sensors) failure diagnosis, and (4) real-time corrective measure synthesis. The MOAS methodology was used for the NORS (Nokia Research Simulator) process at the Halden man-machine laboratory HAMMLAB of the OECD Halden reactor project. The performance tests of MOAS, implemented in G2 real-time expert system shell, show that MOAS successfully carries out its intended functions, i.e. quickly recognizing an occurring disturbance, correctly diagnosing its cause, and presenting advice on its control to the operator. The lessons learned and insights gained during the implementation and performance tests also are discussed

A Quality-Driven Methodology for Information Systems Integration

Directory of Open Access Journals (Sweden)

Iyad Zikra

2017-10-01

Full Text Available Information systems integration is an essential instrument for organizations to attain advantage in today’s growing and fast changing business and technology landscapes. Integration solutions generate added value by combining the functionality and services of heterogeneous and diverse systems. Existing integration environments tend to rely heavily on technical, platform-dependent skills. Consequently, the solutions that they enable are not optimally aligned with the envisioned business goals of the organization. Furthermore, the gap between the goals and the solutions complicates the task of evaluating the quality of integration solutions. To address these challenges, we propose a quality-driven, model-driven methodology for designing and developing integration solutions. The methodology spans organizational and systems design details, providing a holistic view of the integration solution and its underlying business goals. A multi-view meta-model provides the basis for the integration design. Quality factors that affect various aspects of the integration solution guide and inform the progress of the methodology. An example business case is presented to demonstrate the application of the methodology.

Synthesis-Spectroscopy Roadmap Problems: Discovering Organic Chemistry

Science.gov (United States)

Kurth, Laurie L.; Kurth, Mark J.

2014-01-01

Organic chemistry problems that interrelate and integrate synthesis with spectroscopy are presented. These synthesis-spectroscopy roadmap (SSR) problems uniquely engage second-year undergraduate organic chemistry students in the personal discovery of organic chemistry. SSR problems counter the memorize-or-bust strategy that many students tend to…

Integrated Nuclear-Renewable Energy Systems: Foundational Workshop Report

International Nuclear Information System (INIS)

2014-01-01

The U.S. Department of Energy (DOE) recognizes the need to transform the energy infrastructure of the U.S. and elsewhere to systems that can drastically reduce environmental impacts in an efficient and economically viable manner while utilizing both hydrocarbon resources and clean energy generation sources. Thus, DOE is supporting research and development that could lead to more efficient utilization of clean energy generation sources, including renewable and nuclear options. A concept being advanced by the DOE Offices of Nuclear Energy (NE) and Energy Efficiency and Renewable Energy (EERE) is tighter coupling of nuclear and renewable energy sources in a manner that produces new energy currency for the combined electricity grid, industrial manufacturing, and the transportation energy sectors. This integration concept has been referred to as a ''hybrid system'' that is capable of providing the right type of energy, at the right time, in the right place. At the direction of DOE-NE and DOE-EERE leadership, project leads at Idaho National Laboratory (INL), National Renewable Energy Laboratory (NREL) and Massachusetts Institute of Technology (MIT) have identified and engaged stakeholders in discussing integrated energy systems that would optimize renewable and nuclear energy integration on a region-by-region basis. Subsequent work will entail conduct of technical, economic, environmental and socio-political evaluations of the leading integrated system options based on a set of criteria established with stakeholder input. The Foundational Workshop for Integrated Nuclear - Renewable Energy Systems was organized around the following objectives: 1. Identify and refine priority region-specific opportunities for integrated nuclear-renewable energy systems in the U.S.; 2. Select Figures of Merit (FOM) to rank and prioritize candidate systems; 3. Discuss enabling technology development needs; 4. Identify analysis requirements, capabilities and gaps to

Integrated nonthermal treatment system study

International Nuclear Information System (INIS)

Biagi, C.; Bahar, D.; Teheranian, B.; Vetromile, J.; Quapp, W.J.; Bechtold, T.; Brown, B.; Schwinkendorf, W.; Swartz, G.

1997-01-01

This report presents the results of a study of nonthermal treatment technologies. The study consisted of a systematic assessment of five nonthermal treatment alternatives. The treatment alternatives consist of widely varying technologies for safely destroying the hazardous organic components, reducing the volume, and preparing for final disposal of the contact-handled mixed low-level waste (MLLW) currently stored in the US Department of Energy complex. The alternatives considered were innovative nonthermal treatments for organic liquids and sludges, process residue, soil and debris. Vacuum desorption or various washing approaches are considered for treatment of soil, residue and debris. Organic destruction methods include mediated electrochemical oxidation, catalytic wet oxidation, and acid digestion. Other methods studied included stabilization technologies and mercury separation of treatment residues. This study is a companion to the integrated thermal treatment study which examined 19 alternatives for thermal treatment of MLLW waste. The quantities and physical and chemical compositions of the input waste are based on the inventory database developed by the US Department of Energy. The Integrated Nonthermal Treatment Systems (INTS) systems were evaluated using the same waste input (2,927 pounds per hour) as the Integrated Thermal Treatment Systems (ITTS). 48 refs., 68 figs., 37 tabs

Integrated nonthermal treatment system study

Energy Technology Data Exchange (ETDEWEB)

Biagi, C.; Bahar, D.; Teheranian, B.; Vetromile, J. [Morrison Knudsen Corp. (United States); Quapp, W.J. [Nuclear Metals (United States); Bechtold, T.; Brown, B.; Schwinkendorf, W. [Lockheed Martin Idaho Technologies Co., Idaho Falls, ID (United States); Swartz, G. [Swartz and Associates (United States)

1997-01-01

This report presents the results of a study of nonthermal treatment technologies. The study consisted of a systematic assessment of five nonthermal treatment alternatives. The treatment alternatives consist of widely varying technologies for safely destroying the hazardous organic components, reducing the volume, and preparing for final disposal of the contact-handled mixed low-level waste (MLLW) currently stored in the US Department of Energy complex. The alternatives considered were innovative nonthermal treatments for organic liquids and sludges, process residue, soil and debris. Vacuum desorption or various washing approaches are considered for treatment of soil, residue and debris. Organic destruction methods include mediated electrochemical oxidation, catalytic wet oxidation, and acid digestion. Other methods studied included stabilization technologies and mercury separation of treatment residues. This study is a companion to the integrated thermal treatment study which examined 19 alternatives for thermal treatment of MLLW waste. The quantities and physical and chemical compositions of the input waste are based on the inventory database developed by the US Department of Energy. The Integrated Nonthermal Treatment Systems (INTS) systems were evaluated using the same waste input (2,927 pounds per hour) as the Integrated Thermal Treatment Systems (ITTS). 48 refs., 68 figs., 37 tabs.

N-terminally truncated GADD34 proteins are convenient translation enhancers in a human cell-derived in vitro protein synthesis system.

Science.gov (United States)

Mikami, Satoshi; Kobayashi, Tominari; Machida, Kodai; Masutani, Mamiko; Yokoyama, Shigeyuki; Imataka, Hiroaki

2010-07-01

Human cell-derived in vitro protein synthesis systems are useful for the production of recombinant proteins. Productivity can be increased by supplementation with GADD34, a protein that is difficult to express in and purify from E. coli. Deletion of the N-terminal 120 or 240 amino acids of GADD34 improves recovery of this protein from E. coli without compromising its ability to boost protein synthesis in an in vitro protein synthesis system. The use of N-terminally truncated GADD34 proteins in place of full-length GADD34 should improve the utility of human cell-based cell-free protein synthesis systems.

CTBT integrated verification system evaluation model supplement

International Nuclear Information System (INIS)

EDENBURN, MICHAEL W.; BUNTING, MARCUS; PAYNE, ARTHUR C. JR.; TROST, LAWRENCE C.

2000-01-01

Sandia National Laboratories has developed a computer based model called IVSEM (Integrated Verification System Evaluation Model) to estimate the performance of a nuclear detonation monitoring system. The IVSEM project was initiated in June 1994, by Sandia's Monitoring Systems and Technology Center and has been funded by the U.S. Department of Energy's Office of Nonproliferation and National Security (DOE/NN). IVSEM is a simple, ''top-level,'' modeling tool which estimates the performance of a Comprehensive Nuclear Test Ban Treaty (CTBT) monitoring system and can help explore the impact of various sensor system concepts and technology advancements on CTBT monitoring. One of IVSEM's unique features is that it integrates results from the various CTBT sensor technologies (seismic, in sound, radionuclide, and hydroacoustic) and allows the user to investigate synergy among the technologies. Specifically, IVSEM estimates the detection effectiveness (probability of detection), location accuracy, and identification capability of the integrated system and of each technology subsystem individually. The model attempts to accurately estimate the monitoring system's performance at medium interfaces (air-land, air-water) and for some evasive testing methods such as seismic decoupling. The original IVSEM report, CTBT Integrated Verification System Evaluation Model, SAND97-25 18, described version 1.2 of IVSEM. This report describes the changes made to IVSEM version 1.2 and the addition of identification capability estimates that have been incorporated into IVSEM version 2.0

PC driven integrated vacuum system

International Nuclear Information System (INIS)

Curuia, M.; Culcer, M.; Brandea, I.; Anghel, M.

2001-01-01

The paper presents a integrated vacuum system which was designed and manufactured in our institute. The main parts of this system are the power supply unit for turbo-melecular pumps and the vacuummeter. Both parts of the system are driven by means of a personal computer using a serial communication, according to the RS 232 hardware standard.(author)

Optimal Real-time Dispatch for Integrated Energy Systems

DEFF Research Database (Denmark)

Anvari-Moghaddam, Amjad; Guerrero, Josep M.; Rahimi-Kian, Ashkan

2016-01-01

With the emerging of small-scale integrated energy systems (IESs), there are significant potentials to increase the functionality of a typical demand-side management (DSM) strategy and typical implementation of building-level distributed energy resources (DERs). By integrating DSM and DERs...... into a cohesive, networked package that fully utilizes smart energy-efficient end-use devices, advanced building control/automation systems, and integrated communications architectures, it is possible to efficiently manage energy and comfort at the end-use location. In this paper, an ontology-driven multi......-agent control system with intelligent optimizers is proposed for optimal real-time dispatch of an integrated building and microgrid system considering coordinated demand response (DR) and DERs management. The optimal dispatch problem is formulated as a mixed integer nonlinear programing problem (MINLP...

Cost reduction through system integration

International Nuclear Information System (INIS)

Helsing, P.

1994-01-01

In resent years cost reduction has been a key issue in the petroleum industry. Several findings are not economically attractive at the current cost level, and for this and other reasons some of the major oil companies require the suppliers to have implemented a cost reduction programme to prequalify for projects. The present paper addresses cost reduction through system design and integration in both product development and working methods. This is to be obtained by the combination of contracts by reducing unnecessary coordination and allow re-use of proven interface designs, improve subsystem integration by ''top down'' system design, and improve communication and exchange of experience. 3 figs

Formation Mechanism of Spherical TiC in Ni-Ti-C System during Combustion Synthesis.

Science.gov (United States)

Zhu, Guoliang; Wang, Wei; Wang, Rui; Zhao, Chuanbao; Pan, Weitao; Huang, Haijun; Du, Dafan; Wang, Donghong; Shu, Da; Dong, Anping; Sun, Baode; Jiang, Sheng; Pu, Yilong

2017-08-29

The formation mechanism of TiC particles in a Ni-Ti-C system were revealed by using differential thermal analysis (DTA), XRD, and SEM to identify the reaction products in different temperature ranges. The results indicated that the synthesis mechanism of TiC in Ni-Ti-C system was complex; several reactions were involved in the combustion synthesis of TiC-Ni composite. The Ni-Ti intermediate phases play important roles during the formation of TiC. Moreover, the influence of heating rate on the size range of TiC was also discussed.

Energy Systems High-Pressure Test Laboratory | Energy Systems Integration

Science.gov (United States)

Facility | NREL Energy Systems High-Pressure Test Laboratory Energy Systems High-Pressure Test Laboratory In the Energy Systems Integration Facility's High-Pressure Test Laboratory, researchers can safely test high-pressure hydrogen components. Photo of researchers running an experiment with a hydrogen fuel

Regional integrated system of separated collection

International Nuclear Information System (INIS)

Markuskova, I.

2008-01-01

Since 2002 Palarikovo manages and ensures Regional integrated system of separated collection. In the present time 28 villages of the region are associated in Association of villages for sustainable treatment of municipal wastes with settlement in Palarikovo. In accordance with hierarchy of goals of national strategy in the field of treatment of municipal wastes the key aims of activity are centred on economical and sustainable treatment of municipal wastes, which consist in reduction of quantity and harmfulness of municipal wastes by destruction by unloading or combustion. The steps for achievement of this aim consist in (1) prevention of formation of wastes, (2) using of usable subjects (establishing of centre for repeated using in Regional collecting court), (3) by rigorous realisation of recycling program - by collection of separated commodities with a view to mainly material recycling as well as composting program. By starting of integrated regional system of separated collection were integrated 18 villages with 24,000 inhabitants into common separated collection. In the present time this association has 28 members (villages of the region) with total population 55,904. Operating of the Regional integrated system of separated collection in Palarikovo is reviewed

Y-12 Integrated Materials Management System

Energy Technology Data Exchange (ETDEWEB)

Alspaugh, D. H.; Hickerson, T. W.

2002-06-03

The Integrated Materials Management System, when fully implemented, will provide the Y-12 National Security Complex with advanced inventory information and analysis capabilities and enable effective assessment, forecasting and management of nuclear materials, critical non-nuclear materials, and certified supplies. These capabilities will facilitate future Y-12 stockpile management work, enhance interfaces to existing National Nuclear Security Administration (NNSA) corporate-level information systems, and enable interfaces to planned NNSA systems. In the current national nuclear defense environment where, for example, weapons testing is not permitted, material managers need better, faster, more complete information about material properties and characteristics. They now must manage non-special nuclear material at the same high-level they have managed SNM, and information capabilities about both must be improved. The full automation and integration of business activities related to nuclear and non-nuclear materials that will be put into effect by the Integrated Materials Management System (IMMS) will significantly improve and streamline the process of providing vital information to Y-12 and NNSA managers. This overview looks at the kinds of information improvements targeted by the IMMS project, related issues, the proposed information architecture, and the progress to date in implementing the system.

Y-12 Integrated Materials Management System

International Nuclear Information System (INIS)

Alspaugh, D. H.; Hickerson, T. W.

2002-01-01

The Integrated Materials Management System, when fully implemented, will provide the Y-12 National Security Complex with advanced inventory information and analysis capabilities and enable effective assessment, forecasting and management of nuclear materials, critical non-nuclear materials, and certified supplies. These capabilities will facilitate future Y-12 stockpile management work, enhance interfaces to existing National Nuclear Security Administration (NNSA) corporate-level information systems, and enable interfaces to planned NNSA systems. In the current national nuclear defense environment where, for example, weapons testing is not permitted, material managers need better, faster, more complete information about material properties and characteristics. They now must manage non-special nuclear material at the same high-level they have managed SNM, and information capabilities about both must be improved. The full automation and integration of business activities related to nuclear and non-nuclear materials that will be put into effect by the Integrated Materials Management System (IMMS) will significantly improve and streamline the process of providing vital information to Y-12 and NNSA managers. This overview looks at the kinds of information improvements targeted by the IMMS project, related issues, the proposed information architecture, and the progress to date in implementing the system

Almost Poisson integration of rigid body systems

International Nuclear Information System (INIS)

Austin, M.A.; Krishnaprasad, P.S.; Li-Sheng Wang

1993-01-01

In this paper we discuss the numerical integration of Lie-Poisson systems using the mid-point rule. Since such systems result from the reduction of hamiltonian systems with symmetry by lie group actions, we also present examples of reconstruction rules for the full dynamics. A primary motivation is to preserve in the integration process, various conserved quantities of the original dynamics. A main result of this paper is an O(h 3 ) error estimate for the Lie-Poisson structure, where h is the integration step-size. We note that Lie-Poisson systems appear naturally in many areas of physical science and engineering, including theoretical mechanics of fluids and plasmas, satellite dynamics, and polarization dynamics. In the present paper we consider a series of progressively complicated examples related to rigid body systems. We also consider a dissipative example associated to a Lie-Poisson system. The behavior of the mid-point rule and an associated reconstruction rule is numerically explored. 24 refs., 9 figs

Coal Integrated Gasification Fuel Cell System Study

Energy Technology Data Exchange (ETDEWEB)

Chellappa Balan; Debashis Dey; Sukru-Alper Eker; Max Peter; Pavel Sokolov; Greg Wotzak

2004-01-31

This study analyzes the performance and economics of power generation systems based on Solid Oxide Fuel Cell (SOFC) technology and fueled by gasified coal. System concepts that integrate a coal gasifier with a SOFC, a gas turbine, and a steam turbine were developed and analyzed for plant sizes in excess of 200 MW. Two alternative integration configurations were selected with projected system efficiency of over 53% on a HHV basis, or about 10 percentage points higher than that of the state-of-the-art Integrated Gasification Combined Cycle (IGCC) systems. The initial cost of both selected configurations was found to be comparable with the IGCC system costs at approximately $1700/kW. An absorption-based CO2 isolation scheme was developed, and its penalty on the system performance and cost was estimated to be less approximately 2.7% and $370/kW. Technology gaps and required engineering development efforts were identified and evaluated.

Integrated environment, safety, and health management system description

International Nuclear Information System (INIS)

Zoghbi, J. G.

2000-01-01

The Integrated Environment, Safety, and Health Management System Description that is presented in this document describes the approach and management systems used to address integrated safety management within the Richland Environmental Restoration Project

Integrated Nuclear-Renewable Energy Systems: Foundational Workshop Report

Energy Technology Data Exchange (ETDEWEB)

Bragg-Sitton, Shannon [Idaho National Lab. (INL), Idaho Falls, ID (United States); Boardman, Richard [Idaho National Lab. (INL), Idaho Falls, ID (United States); Ruth, Mark [National Renewable Energy Lab. (NREL), Golden, CO (United States); Zinaman, Owen [National Renewable Energy Lab. (NREL), Golden, CO (United States); Forsberg, Charles [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Collins, John [Idaho National Lab. (INL), Idaho Falls, ID (United States)

2014-08-01

The U.S. Department of Energy (DOE) recognizes the need to transform the energy infrastructure of the U.S. and elsewhere to systems that can drastically reduce environmental impacts in an efficient and economically viable manner while utilizing both hydrocarbon resources and clean energy generation sources. Thus, DOE is supporting research and development that could lead to more efficient utilization of clean energy generation sources, including renewable and nuclear options. A concept being advanced by the DOE Offices of Nuclear Energy (NE) and Energy Efficiency and Renewable Energy (EERE) is tighter coupling of nuclear and renewable energy sources in a manner that produces new energy currency for the combined electricity grid, industrial manufacturing, and the transportation energy sectors. This integration concept has been referred to as a “hybrid system” that is capable of providing the right type of energy, at the right time, in the right place. At the direction of DOE-NE and DOE-EERE leadership, project leads at Idaho National Laboratory (INL), National Renewable Energy Laboratory (NREL) and Massachusetts Institute of Technology (MIT) have identified and engaged stakeholders in discussing integrated energy systems that would optimize renewable and nuclear energy integration on a region-by-region basis. Subsequent work will entail conduct of technical, economic, environmental and socio-political evaluations of the leading integrated system options based on a set of criteria established with stakeholder input. The Foundational Workshop for Integrated Nuclear – Renewable Energy Systems was organized around the following objectives: 1. Identify and refine priority region-specific opportunities for integrated nuclear-renewable energy systems in the U.S.; 2. Select Figures of Merit (FOM) to rank and prioritize candidate systems; 3. Discuss enabling technology development needs; 4. Identify analysis requirements, capabilities and gaps to estimate FOM for

Distributed PROMPT-LTL Synthesis

Directory of Open Access Journals (Sweden)

Swen Jacobs

2016-09-01

Full Text Available We consider the synthesis of distributed implementations for specifications in Prompt Linear Temporal Logic (PROMPT-LTL, which extends LTL by temporal operators equipped with parameters that bound their scope. For single process synthesis it is well-established that such parametric extensions do not increase worst-case complexities. For synchronous systems, we show that, despite being more powerful, the distributed realizability problem for PROMPT-LTL is not harder than its LTL counterpart. For asynchronous systems we have to consider an assume-guarantee synthesis problem, as we have to express scheduling assumptions. As asynchronous distributed synthesis is already undecidable for LTL, we give a semi-decision procedure for the PROMPT-LTL assume-guarantee synthesis problem based on bounded synthesis.

Guarani aquifer hydrogeological synthesis of the Guarani aquifer system. Edicion bilingue

International Nuclear Information System (INIS)

2009-01-01

This work represents the synthesis of current knowledge of the Guarani Aquifer System, based on technical products made by different companies and consultants who participated in the framework of the Project for Environmental Protection and Sustainable Development of the Guarani Aquifer.

Regulation of aortic extracellular matrix synthesis via noradrenergic system and angiotensin II in juvenile rats.

Science.gov (United States)

Dab, Houcine; Hachani, Rafik; Dhaouadi, Nedra; Sakly, Mohsen; Hodroj, Wassim; Randon, Jacques; Bricca, Giampiero; Kacem, Kamel

2012-10-01

Extracellular matrix (ECM) synthesis regulation by sympathetic nervous system (SNS) or angiotensin II (ANG II) was widely reported, but interaction between the two systems on ECM synthesis needs further investigation. We tested implication of SNS and ANG II on ECM synthesis in juvenile rat aorta. Sympathectomy with guanethidine (50 mg/kg, subcutaneous) and blockade of the ANG II AT1 receptors (AT1R) blocker with losartan (20 mg/kg/day in drinking water) were performed alone or in combination in rats. mRNA and protein synthesis of collagen and elastin were examined by Q-RT-PCR and immunoblotting. Collagen type I and III mRNA were increased respectively by 62 and 43% after sympathectomy and decreased respectively by 31 and 60% after AT1R blockade. Combined treatment increased collagen type III by 36% but not collagen type I. The same tendency of collagen expression was observed at mRNA and protein levels after the three treatments. mRNA and protein level of elastin was decreased respectively by 63 and 39% and increased by 158 and 15% after losartan treatment. Combined treatment abrogates changes induced by single treatments. The two systems act as antagonists on ECM expression in the aorta and combined inhibition of the two systems prevents imbalance of mRNA and protein level of collagen I and elastin induced by single treatment. Combined inhibition of the two systems prevents deposit or excessive reduction of ECM and can more prevent cardiovascular disorders.

Integrated Systems Mitigate Land Degradation and Improve Agricultural System Sustainability

Science.gov (United States)

Landblom, Douglas; Senturklu, Songul; Cihacek, Larry; Brevik, Eric

2017-04-01

Rain-fed agricultural production supported by exogenous inputs is not sustainable because a continuous influx of expensive inputs (fertilizer, chemicals, fossil fuel, labor, tillage, and other) is required. Alternatives to traditional management allow natural occurring dynamic soil processes to provide the necessary microbial activity that supports nutrient cycling in balance with nature. Research designed to investigate the potential for integrated systems to replace expensive inputs has shown that healthy soils rich in soil organic matter (SOM) are the foundation upon which microbial nutrient cycling can reduce and eventually replace expensive fertilizer. No-till seed placement technology effectively replaces multiple-pass cultivation conserving stored soil water in semi-arid farming systems. In multi-crop rotations, cool- and warm-season crops are grown in sequence to meet goals of the integrated farming and ranching system, and each crop in the rotation complements the subsequent crop by supplying a continuous flow of essential SOM for soil nutrient cycling. Grazing animals serve an essential role in the system's sustainability as non-mechanized animal harvesters that reduce fossil fuel consumption and labor, and animal waste contributes soil nutrients to the system. Integrated systems' complementarity has contributed to greater soil nutrient cycling and crop yields, fertilizer reduction or elimination, greater yearling steer grazing net return, reduced cow wintering costs grazing crop residues, increased wildlife sightings, and reduced environmental footprint. Therefore, integrating crop and animal systems can reverse soil quality decline and adopting non-traditional procedures has resulted in a wider array of opportunities for sustainable agriculture and profitability.

Integrated crop protection as a system approach

OpenAIRE

Haan, de, J.J.; Wijnands, F.G.; Sukkel, W.

2005-01-01

New farming systems in vegetable production are required as demands for high quality products that do not pollute the environment are rising, and production risks are large and incomes low. The methodology of prototyping new systems is described, especially the themes, parameters and target values connected to integrated crop protection. The role of integrated crop protection in prototyping new systems is discussed. The results of twenty years working with this prototyping methodology are pre...

Establishment of key grid-connected performance index system for integrated PV-ES system

Science.gov (United States)

Li, Q.; Yuan, X. D.; Qi, Q.; Liu, H. M.

2016-08-01

In order to further promote integrated optimization operation of distributed new energy/ energy storage/ active load, this paper studies the integrated photovoltaic-energy storage (PV-ES) system which is connected with the distribution network, and analyzes typical structure and configuration selection for integrated PV-ES generation system. By combining practical grid- connected characteristics requirements and technology standard specification of photovoltaic generation system, this paper takes full account of energy storage system, and then proposes several new grid-connected performance indexes such as paralleled current sharing characteristic, parallel response consistency, adjusting characteristic, virtual moment of inertia characteristic, on- grid/off-grid switch characteristic, and so on. A comprehensive and feasible grid-connected performance index system is then established to support grid-connected performance testing on integrated PV-ES system.

Reducing acquisition risk through integrated systems of systems engineering

Science.gov (United States)

Gross, Andrew; Hobson, Brian; Bouwens, Christina

2016-05-01

In the fall of 2015, the Joint Staff J7 (JS J7) sponsored the Bold Quest (BQ) 15.2 event and conducted planning and coordination to combine this event into a joint event with the Army Warfighting Assessment (AWA) 16.1 sponsored by the U.S. Army. This multipurpose event combined a Joint/Coalition exercise (JS J7) with components of testing, training, and experimentation required by the Army. In support of Assistant Secretary of the Army for Acquisition, Logistics, and Technology (ASA(ALT)) System of Systems Engineering and Integration (SoSE&I), Always On-On Demand (AO-OD) used a system of systems (SoS) engineering approach to develop a live, virtual, constructive distributed environment (LVC-DE) to support risk mitigation utilizing this complex and challenging exercise environment for a system preparing to enter limited user test (LUT). AO-OD executed a requirements-based SoS engineering process starting with user needs and objectives from Army Integrated Air and Missile Defense (AIAMD), Patriot units, Coalition Intelligence, Surveillance and Reconnaissance (CISR), Focused End State 4 (FES4) Mission Command (MC) Interoperability with Unified Action Partners (UAP), and Mission Partner Environment (MPE) Integration and Training, Tactics and Procedures (TTP) assessment. The SoS engineering process decomposed the common operational, analytical, and technical requirements, while utilizing the Institute of Electrical and Electronics Engineers (IEEE) Distributed Simulation Engineering and Execution Process (DSEEP) to provide structured accountability for the integration and execution of the AO-OD LVC-DE. As a result of this process implementation, AO-OD successfully planned for, prepared, and executed a distributed simulation support environment that responsively satisfied user needs and objectives, demonstrating the viability of an LVC-DE environment to support multiple user objectives and support risk mitigation activities for systems in the acquisition process.

Loop containment (joint integrity) assessment Brayton Isotope Power System flight system

International Nuclear Information System (INIS)

1976-01-01

The Brayton Isotope Power System (BIPS) contains a large number of joints. Since the failure of a joint would result in loss of the working fluid and consequential failure of the BIPS, the integrity of the joints is of paramount importance. The reliability of the ERDA BIPS loop containment (joint integrity) is evaluated. The conceptual flight system as presently configured is depicted. A brief description of the flight system is given

Design and Synthesis of Distillation Systems using a Driving Force Based Approach

DEFF Research Database (Denmark)

Bek-Pedersen, Erik; Gani, Rafiqul

2004-01-01

A new integrated framework for synthesis, design and operation of distillation-based separation schemes is presented here. This framework is based on the driving force approach, which provides a measure of the differences in chemical/physical properties between two co-existing phases...... in a separation unit. A set of algorithms has been developed within this framework for design of simple as well as complex distillation columns, for the sequencing of distillation trains, for the determination of appropriate conditions of operation and for retrofit of distillation columns. The main feature of all...... these algorithms is that they provide a simple "visual" method to obtain near-optimal solutions in terms of energy consumption without rigorous simulation and/or optimisation. Several illustrative examples highlighting the application of the integrated approach are also presented. (C) 2003 Published by Elsevier B.V....

Integrated material accountancy system

International Nuclear Information System (INIS)

Calabozo, M.; Buiza, A.

1991-01-01

In this paper we present the system that we are actually using for Nuclear Material Accounting and Manufacturing Management in our UO 2 Fuel Fabrication Plant located at Juzbado, Salamanca, Spain. The system is based mainly on a real time data base which gather data for all the operations performed in our factory from UO 2 powder reception to fuel assemblies shipment to the customers. The accountancy is just an important part of the whole integrated system covering all the aspects related to manufacturing: planning, traceability, Q.C. analysis, production control and accounting data

Integrated programs for women with substance use issues and their children: a qualitative meta-synthesis of processes and outcomes

Directory of Open Access Journals (Sweden)

Thabane Lehana

2009-01-01

Full Text Available Abstract Background There is a need for services that effectively and comprehensively address the complex needs of women with substance use issues and their children. A growing body of literature supports the relevance of integrated treatment programs that offer a wide range of services in centralized settings. Quantitative studies suggest that these programs are associated with positive outcomes. A qualitative meta-synthesis was conducted to provide insight into the processes that contribute to recovery in integrated programs and women's perceptions of benefits for themselves and their children. Methods A comprehensive search of published and unpublished literature to August 2009 was carried out for narrative reports of women's experiences and perceptions of integrated treatment programs. Eligibility for inclusion in the meta-synthesis was determined using defined criteria. Quality assessment was then conducted. Qualitative data and interpretations were extracted from studies of adequate quality, and were synthesized using a systematic and iterative process to create themes and overarching concepts. Results A total of 15 documents were included in the meta-synthesis. Women experienced a number of psychosocial processes during treatment that played a role in their recovery and contributed to favourable outcomes. These included: development of a sense of self; development of personal agency; giving and receiving of social support; engagement with program staff; self-disclosure of challenges, feelings, and past experiences; recognizing patterns of destructive behaviour; and goal setting. A final process, the motivating presence of children, sustained women in their recovery journeys. Perceived outcomes included benefits for maternal and child well-being, and enhanced parenting capacity. Conclusion A number of distinct but interconnected processes emerged as being important to women's addiction recovery. Women experienced individual growth and

Integrability of dynamical systems algebra and analysis

CERN Document Server

Zhang, Xiang

2017-01-01

This is the first book to systematically state the fundamental theory of integrability and its development of ordinary differential equations with emphasis on the Darboux theory of integrability and local integrability together with their applications. It summarizes the classical results of Darboux integrability and its modern development together with their related Darboux polynomials and their applications in the reduction of Liouville and elementary integrabilty and in the center—focus problem, the weakened Hilbert 16th problem on algebraic limit cycles and the global dynamical analysis of some realistic models in fields such as physics, mechanics and biology. Although it can be used as a textbook for graduate students in dynamical systems, it is intended as supplementary reading for graduate students from mathematics, physics, mechanics and engineering in courses related to the qualitative theory, bifurcation theory and the theory of integrability of dynamical systems.

CTBT integrated verification system evaluation model supplement

Energy Technology Data Exchange (ETDEWEB)

EDENBURN,MICHAEL W.; BUNTING,MARCUS; PAYNE JR.,ARTHUR C.; TROST,LAWRENCE C.

2000-03-02

Sandia National Laboratories has developed a computer based model called IVSEM (Integrated Verification System Evaluation Model) to estimate the performance of a nuclear detonation monitoring system. The IVSEM project was initiated in June 1994, by Sandia's Monitoring Systems and Technology Center and has been funded by the U.S. Department of Energy's Office of Nonproliferation and National Security (DOE/NN). IVSEM is a simple, ''top-level,'' modeling tool which estimates the performance of a Comprehensive Nuclear Test Ban Treaty (CTBT) monitoring system and can help explore the impact of various sensor system concepts and technology advancements on CTBT monitoring. One of IVSEM's unique features is that it integrates results from the various CTBT sensor technologies (seismic, in sound, radionuclide, and hydroacoustic) and allows the user to investigate synergy among the technologies. Specifically, IVSEM estimates the detection effectiveness (probability of detection), location accuracy, and identification capability of the integrated system and of each technology subsystem individually. The model attempts to accurately estimate the monitoring system's performance at medium interfaces (air-land, air-water) and for some evasive testing methods such as seismic decoupling. The original IVSEM report, CTBT Integrated Verification System Evaluation Model, SAND97-25 18, described version 1.2 of IVSEM. This report describes the changes made to IVSEM version 1.2 and the addition of identification capability estimates that have been incorporated into IVSEM version 2.0.

Integrating systems biology models and biomedical ontologies.

Science.gov (United States)

Hoehndorf, Robert; Dumontier, Michel; Gennari, John H; Wimalaratne, Sarala; de Bono, Bernard; Cook, Daniel L; Gkoutos, Georgios V

2011-08-11

Systems biology is an approach to biology that emphasizes the structure and dynamic behavior of biological systems and the interactions that occur within them. To succeed, systems biology crucially depends on the accessibility and integration of data across domains and levels of granularity. Biomedical ontologies were developed to facilitate such an integration of data and are often used to annotate biosimulation models in systems biology. We provide a framework to integrate representations of in silico systems biology with those of in vivo biology as described by biomedical ontologies and demonstrate this framework using the Systems Biology Markup Language. We developed the SBML Harvester software that automatically converts annotated SBML models into OWL and we apply our software to those biosimulation models that are contained in the BioModels Database. We utilize the resulting knowledge base for complex biological queries that can bridge levels of granularity, verify models based on the biological phenomenon they represent and provide a means to establish a basic qualitative layer on which to express the semantics of biosimulation models. We establish an information flow between biomedical ontologies and biosimulation models and we demonstrate that the integration of annotated biosimulation models and biomedical ontologies enables the verification of models as well as expressive queries. Establishing a bi-directional information flow between systems biology and biomedical ontologies has the potential to enable large-scale analyses of biological systems that span levels of granularity from molecules to organisms.

Camels, Cormorants, and Kangaroo Rats: Integration and Synthesis in Organismal Biology After World War II.

Science.gov (United States)

Hagen, Joel B

2015-01-01

During the decades following World War II diverse groups of American biologists established a variety of distinctive approaches to organismal biology. Rhetorically, organismal biology could be used defensively to distinguish established research traditions from perceived threats from newly emerging fields such as molecular biology. But, organismal biologists were also interested in integrating biological disciplines and using a focus on organisms to synthesize levels of organization from molecules and cells to populations and communities. Part of this broad movement was the development of an area of research variously referred to as physiological ecology, environmental physiology, or ecophysiology. This area of research was distinctive in its self-conscious blend of field and laboratory practices and its explicit integration with other areas of biology such as ecology, animal behavior, and evolution in order to study adaptation. Comparing the intersecting careers of Knut Schmidt-Nielsen and George Bartholomew highlights two strikingly different approaches to physiological ecology. These alternative approaches to studying the interactions of organisms and environments also differed in important ways from the organismal biology championed by leading figures in the modern synthesis.

Energy Systems Integration: Demonstrating Distribution Feeder Voltage Control

Energy Technology Data Exchange (ETDEWEB)

2017-01-01

Overview fact sheet about the Smarter Grid Solutions Integrated Network Testbed for Energy Grid Research and Technology Experimentation (INTEGRATE) project at the Energy Systems Integration Facility. INTEGRATE is part of the U.S. Department of Energy's Grid Modernization Initiative.

The integrated manual and automatic control of complex flight systems

Science.gov (United States)

Schmidt, David K.

1991-01-01

Research dealt with the general area of optimal flight control synthesis for manned flight vehicles. The work was generic; no specific vehicle was the focus of study. However, the class of vehicles generally considered were those for which high authority, multivariable control systems might be considered, for the purpose of stabilization and the achievement of optimal handling characteristics. Within this scope, the topics of study included several optimal control synthesis techniques, control-theoretic modeling of the human operator in flight control tasks, and the development of possible handling qualities metrics and/or measures of merit. Basic contributions were made in all these topics, including human operator (pilot) models for multi-loop tasks, optimal output feedback flight control synthesis techniques; experimental validations of the methods developed, and fundamental modeling studies of the air-to-air tracking and flared landing tasks.

On the integrability of some generalized Lotka-Volterra systems

Science.gov (United States)

Bier, M.; Hijmans, J.; Bountis, T. C.

1983-08-01

Several integrable systems of nonlinear ordinary differential equations of the Lotka-Volterra type are identified by the Painleveproperty and completely integrated. One such integrable case of N first order ode's is found, with N-2 free parameters and N arbitrary. The concept of integrability of a general dynamical system, not necessarily derived from a Hamiltonian, is also discussed.

FORMATION OF THE SYNTHESIS ALGORITHMS OF THE COORDINATING CONTROL SYSTEMS BY MEANS OF THE AUTOMATIC GENERATION OF PETRI NETS

Directory of Open Access Journals (Sweden)

A. A. Gurskiy

2016-09-01

Full Text Available The coordinating control system by drives of the robot-manipulator is presented in this article. The purpose of the scientific work is the development and research of the new algorithms for parametric synthesis of the coordinating control systems. To achieve this aim it is necessary to develop the system generating the required parametric synthesis algorithms and performing the necessary procedures according to the generated algorithm. This scientific work deals with the synthesis of Petri net in the specific case with the automatic generation of Petri nets.

Basic principles, contents, and benefits of an integrated management system

International Nuclear Information System (INIS)

Schwarzin, Juergen

2010-01-01

The basic principles and contents of an integrated management system are presented. The report focuses on the benefits and the experience accumulated in using an integrated management system. Integrated management systems are characterized by 2 features in particular: - On the one hand, by a system holistically controlling and describing all processes within a company which are necessary to achieve the company policy and company goals as defined. - On the other hand, it combines in one integrated management system various different aspects (such as quality, environmental protection, and safety) and the resulting requirements. Successful implementation of an integrated management system requires a clear commitment by company management to the integrated management system serving as a management tool. Implementation must be assigned the appropriate importance in the company. It must not be viewed as an instrument preserving 'status quo.' Instead, it must be seen as a tool for long-term improvement of the company. Application of the integrated management system minimizes the probability of occurrence of events, but is not able to reduce it to zero. (orig.)

THE PLACE OF OCCUPATIONAL HEALTH AND SAFETY MANAGEMENT SYSTEM IN THE INTEGRATED MANAGEMENT SYSTEM

Directory of Open Access Journals (Sweden)

Piotr Kafel

2016-06-01

Full Text Available The purpose of this paper is to analyze the place of occupational health and safety management system (OHSMS within the integrated management system. Implementation aspects of management systems are discussed, namely the different management system standards used for registration, for example ISO 14001, ISO 9001, OHSAS 18001, ISO 27001, the order in which they were implemented, the time required for each implementation, as well as the scope of integration of these management system standards into a single Integrated Management System and the level of integration. In order to do so, some of the results of a survey carried out in 81 organizations registered to at least two management systems selected from popular international standards, e.g.: ISO 9001, ISO 14001, OHSAS 18001, ISO/IEC 27001, ISO 22000 were used. OHSMS is not the system that is implemented as a first one. Usually it is implemented after or simultaneously with ISO 9001 and ISO 14001 standards. Time of implementation of MSSs in second and further round of implementation is shorter than during the implementation of first standards. There is a higher level of integration of implemented management standards in organizations where one of the standards in OHSMS, than in a companies without OHSMS. The paper analyses those sequences of management systems implementation of safety management systems with other system, that allow organizations to achieve higher levels of integration and presents a possible pattern for the companies initiating the integration process.

A Facile Solvothermal Synthesis of Octahedral Fe3O4 Nanoparticles

Energy Technology Data Exchange (ETDEWEB)

Ooi, Frances; DuChene, Joseph S.; Qiu, Jianqing; Graham, Jeremy O.; Engelhard, Mark H.; Cao, Guixin; Gai, Zheng; Wei, Wei

2015-06-01

Magnetic nanoparticles are of great technological interest because they promise numerous potential opportunities in biomedicine and data storage. Although intriguing, these applications require exquisite control over nanostructure morphology in order to appropriately harness their magnetic properties. Most synthesis strategies reported to date are unable to routinely produce anisotropic Fe3O4 nanostructures with appropriate sizes to enable integration into biological systems. Here, we report a simple solvothermal synthesis for obtaining octahedral Fe3O4 nanoparticles with suitable sizes for cellular internalization. Furthermore, these ferromagnetic Fe3O4 octahedrons exhibit substantial saturation magnetization with minimal remanence, suggesting their potential applicability for a host of biomedical applications.

Research on Integration of NPP Operational Safety Management Performance Systems

International Nuclear Information System (INIS)

Chi, Miao; Shi, Liping

2014-01-01

The operational safety management of Nuclear Power Plants demands systematic planning and integrated control. NPPs are following the well-developed safety indicator systems proposed by IAEA Operational Safety Performance Indicator Programme, NRC Reactor Oversight Process or the other institutions. Integration of the systems is proposed to benefiting from the advantages of both systems and avoiding improper application into the real world. The authors analyzed the possibility and necessity for system integration, and propose an indicator system integrating method

Synthesis and Design of Processing Networks

DEFF Research Database (Denmark)

Quaglia, Alberto; Sarup, Bent; Sin, Gürkan

2012-01-01

In this contribution, we propose an integrated business and engineering framework for synthesis and design of processing networks under uncertainty. In our framework, an adapted formulation of the transhipment problem is integrated with a superstructure, leading to a Stochastic Mixed Integer Non...... under market and technical uncertainty....

Perspectives on integrating the US radioactive waste disposal system

International Nuclear Information System (INIS)

Culler, F.L.; Croff, A.G.

1990-01-01

The waste management systems being developed and deployed by the DOE Office of Civilian Radioactive Waste Management (OCRWM) is large, complex, decentralized, and long term. As a result, a systems integration approach has been implemented by OCRWM. The fundamentals of systems integration and its application are examined in the context of the OCRWM program. This application is commendable, and some additional systems integration features are suggested to enhance its benefits. 6 refs., 1 fig

An integrated system for pipeline condition monitoring

Energy Technology Data Exchange (ETDEWEB)

Strong, Andrew P.; Lees, Gareth; Hartog, Arthur; Twohig, Richard; Kader, Kamal; Hilton, Graeme; Mullens, Stephen; Khlybov, Artem [Schlumberger, Southampton (United Kingdom); Sanderson, Norman [BP Exploration, Sunbury (United Kingdom)

2009-07-01

In this paper we present the unique and innovative 'Integriti' pipeline and flow line integrity monitoring system developed by Schlumberger in collaboration with BP. The system uses optical fiber distributed sensors to provide simultaneous distributed measurements of temperature, strain and vibration for the detection, monitoring, and location of events including: Third Party Interference (TPI), including multiple simultaneous disturbances; geo-hazards and landslides; gas and oil leaks; permafrost protection. The Integriti technology also provides a unique means for tracking the progress of cleaning and instrumented pigs using existing optical telecom and data communications cables buried close to pipelines. The Integriti solution provides a unique and proactive approach to pipeline integrity management. It performs analysis of a combination of measurands to provide the pipeline operator with an event recognition and location capability, in effect providing a hazard warning system, and offering the operator the potential to take early action to prevent loss. Through the use of remote, optically powered amplification, an unprecedented detection range of 100 km is possible without the need for any electronics and therefore remote power in the field. A system can thus monitor 200 km of pipeline when configured to monitor 100 km upstream and downstream from a single location. As well as detecting conditions and events leading to leaks, this fully integrated system provides a means of detecting and locating small leaks in gas pipelines below the threshold of present online leak detection systems based on monitoring flow parameters. Other significant benefits include: potential reductions in construction costs; enhancement of the operator's existing integrity management program; potential reductions in surveillance costs and HSE risks. In addition to onshore pipeline systems this combination of functionality and range is available for practicable

Integrated CAE system for nuclear power plants. Development of piping design check system

International Nuclear Information System (INIS)

Narikawa, Noboru; Sato, Teruaki

1994-01-01

Toshiba Corporation has developed and operated the integrated CAE system for nuclear power plants, the core of which is the engineering data base to manage accurately and efficiently enormous amount of data on machinery, equipment and piping. As the first step of putting knowledge base system to practical use, piping design check system has been developed. By automatically checking up piping design, this system aims at the prevention of overlooking mistakes, efficient design works and the overall quality improvement of design. This system is based on the thought that it supports designers, and final decision is made by designers. This system is composed of the integrated data base, a two-dimensional CAD system and three-dimensional CAD system. The piping design check system is one of the application systems of the integrated CAE system. Object-oriented programming is the base of the piping design check system, and design knowledge and CAD data are necessary. As to the method of realizing the check system, the flow of piping design, the checkup functions, the checkup of interference and attribute base, and the integration of the system are explained. (K.I)

Increased proteoglycan synthesis by the cardiovascular system of coarctation hypertensive rats

International Nuclear Information System (INIS)

Lipke, D.W.; Couchman, J.R.

1991-01-01

Proteoglycan (PG) synthesis in the cardiovascular system of coarctation hypertensive rats was examined by in vivo and in vitro labeling of glycosaminoglycans with 35SO4 in rats made hypertensive for short (4 days) and longer (14 days) durations. With in vivo labeling, only tissues directly exposed to elevated pressure (left ventricle, LV and aorta above the clip, AOR increases) exhibited elevated PG synthesis after 4 days of hypertension. By 14 days, tissues both exposed to (LV and AOR increases) and protected from elevated pressure (right ventricle and kidney) exhibited elevated PG synthetic rates. Slight elevations in the proportion of galactosaminoglycans were observed with a concurrent proportional decrease in heparan sulfate PGs. Using the in vitro labeling procedure, no significant increases in PG synthesis were observed in any tissue at either 4 days or 14 days of hypertension. These data indicate that: (1) coarctation hypertension stimulates PG production that is dependent initially on increased pressure and later, on additional non-pressure related factors, (2) these other factors are responsible for enhanced PG production in tissues not directly exposed to pressure overload, (3) pressure and/or these other factors are essential for enhanced PG production in coarctation hypertension, and (4) synthesis of all GAG types appears to be affected

Integrated delivery systems: the cure for fragmentation.

Science.gov (United States)

Enthoven, Alain C

2009-12-01

Our healthcare system is fragmented, with a misalignment of incentives, or lack of coordination, that spawns inefficient allocation of resources. Fragmentation adversely impacts quality, cost, and outcomes. Eliminating waste from unnecessary, unsafe care is crucial for improving quality and reducing costs--and making the system financially sustainable. Many believe this can be achieved through greater integration of healthcare delivery, more specifically via integrated delivery systems (IDSs). An IDS is an organized, coordinated, and collaborative network that links various healthcare providers to provide a coordinated, vertical continuum of services to a particular patient population or community. It is also accountable, both clinically and fiscally, for the clinical outcomes and health status of the population or community served, and has systems in place to manage and improve them. The marketplace already contains numerous styles and degrees of integration, ranging from Kaiser Permanente-style full integration, to more loosely organized individual practice associations, to public-private partnerships. Evidence suggests that IDSs can improve healthcare quality, improve outcomes, and reduce costs--especially for patients with complex needs--if properly implemented and coordinated. No single approach or public policy will fix the fragmented healthcare system, but IDSs represent an important step in the right direction.

The computational design of Geological Disposal Technology Integration System

International Nuclear Information System (INIS)

Ishihara, Yoshinao; Iwamoto, Hiroshi; Kobayashi, Shigeki; Neyama, Atsushi; Endo, Shuji; Shindo, Tomonori

2002-03-01

In order to develop 'Geological Disposal Technology Integration System' that is intended to systematize as knowledge base for fundamental study, the computational design of an indispensable database and image processing function to 'Geological Disposal Technology Integration System' was done, the prototype was made for trial purposes, and the function was confirmed. (1) Database of Integration System which systematized necessary information and relating information as an examination of a whole of repository composition and managed were constructed, and the system function was constructed as a system composed of image processing, analytical information management, the repository component management, and the system security function. (2) The range of the data treated with this system and information was examined, the design examination of the database structure was done, and the design examination of the image processing function of the data preserved in an integrated database was done. (3) The prototype of the database concerning a basic function, the system operation interface, and the image processing function was manufactured to verify the feasibility of the 'Geological Disposal Technology Integration System' based on the result of the design examination and the function was confirmed. (author)

Integrated operation of hydro thermal system