Simple group password-based authenticated key agreements for the integrated EPR information system.

Science.gov (United States)

Lee, Tian-Fu; Chang, I-Pin; Wang, Ching-Cheng

2013-04-01

The security and privacy are important issues for electronic patient records (EPRs). The goal of EPRs is sharing the patients' medical histories such as the diagnosis records, reports and diagnosis image files among hospitals by the Internet. So the security issue for the integrated EPR information system is essential. That is, to ensure the information during transmission through by the Internet is secure and private. The group password-based authenticated key agreement (GPAKE) allows a group of users like doctors, nurses and patients to establish a common session key by using password authentication. Then the group of users can securely communicate by using this session key. Many approaches about GAPKE employ the public key infrastructure (PKI) in order to have higher security. However, it not only increases users' overheads and requires keeping an extra equipment for storing long-term secret keys, but also requires maintaining the public key system. This investigation presents a simple group password-based authenticated key agreement (SGPAKE) protocol for the integrated EPR information system. The proposed SGPAKE protocol does not require using the server or users' public keys. Each user only remembers his weak password shared with a trusted server, and then can obtain a common session key. Then all users can securely communicate by using this session key. The proposed SGPAKE protocol not only provides users with convince, but also has higher security.

Executing on Integration: The Key to Success in Mergers and Acquisitions.

Science.gov (United States)

Bradley, Carol

2016-01-01

Health care mergers and acquisitions require a clearly stated vision and exquisite planning of integration activities to provide the best possible conditions for a successful transaction. During the due diligence process, key steps can be taken to create a shared vision and a plan to inspire confidence and build enthusiasm for all stakeholders. Integration planning should include a defined structure, roles and responsibilities, as well as a method for evaluation.

Selection and impedance based model of a lithium ion battery technology for integration with virtual power plant

DEFF Research Database (Denmark)

Swierczynski, Maciej Jozef; Stroe, Daniel Ioan; Stan, Ana-Irina

2013-01-01

is to integrate lithium-ion batteries into virtual power plants; thus, the power system stability and the energy quality can be increased. The selection of the best lithium-ion battery candidate for integration with wind power plants is a key aspect for the economic feasibility of the virtual power plant...... investment. This paper presents a methodology for selection, between three candidates, of a Li-ion battery which offers long cycle lifetime at partial charge/discharge (required by many grid support applications) while providing a low cost per cycle also. For the selected Li-ion battery an impedance......-based diagnostic tool for lifetime estimation was developed and verified. This diagnostic tool can be extended into an impedance-based lifetime model that will be able to predict the remaining useful lifetime of Li-ion batteries for specific grid support applications....

Making mathematics and science integration happen: key aspects of practice

Science.gov (United States)

Ríordáin, Máire Ní; Johnston, Jennifer; Walshe, Gráinne

2016-02-01

The integration of mathematics and science teaching and learning facilitates student learning, engagement, motivation, problem-solving, criticality and real-life application. However, the actual implementation of an integrative approach to the teaching and learning of both subjects at classroom level, with in-service teachers working collaboratively, at second-level education, is under-researched due to the complexities of school-based research. This study reports on a year-long case study on the implementation of an integrated unit of learning on distance, speed and time, within three second-level schools in Ireland. This study employed a qualitative approach and examined the key aspects of practice that impact on the integration of mathematics and science teaching and learning. We argue that teacher perspective, teacher knowledge of the 'other subject' and of technological pedagogical content knowledge (TPACK), and teacher collaboration and support all impact on the implementation of an integrative approach to mathematics and science education.

High-dimensional quantum key distribution based on multicore fiber using silicon photonic integrated circuits

DEFF Research Database (Denmark)

Ding, Yunhong; Bacco, Davide; Dalgaard, Kjeld

2017-01-01

is intrinsically limited to 1 bit/photon. Here we propose and experimentally demonstrate, for the first time, a high-dimensional quantum key distribution protocol based on space division multiplexing in multicore fiber using silicon photonic integrated lightwave circuits. We successfully realized three mutually......-dimensional quantum states, and enables breaking the information efficiency limit of traditional quantum key distribution protocols. In addition, the silicon photonic circuits used in our work integrate variable optical attenuators, highly efficient multicore fiber couplers, and Mach-Zehnder interferometers, enabling...

Reliability criteria selection for integrated resource planning

International Nuclear Information System (INIS)

Ruiu, D.; Ye, C.; Billinton, R.; Lakhanpal, D.

1993-01-01

A study was conducted on the selection of a generating system reliability criterion that ensures a reasonable continuity of supply while minimizing the total costs to utility customers. The study was conducted using the Institute for Electronic and Electrical Engineers (IEEE) reliability test system as the study system. The study inputs and results for conditions and load forecast data, new supply resources data, demand-side management resource data, resource planning criterion, criterion value selection, supply side development, integrated resource development, and best criterion values, are tabulated and discussed. Preliminary conclusions are drawn as follows. In the case of integrated resource planning, the selection of the best value for a given type of reliability criterion can be done using methods similar to those used for supply side planning. The reliability criteria values previously used for supply side planning may not be economically justified when integrated resource planning is used. Utilities may have to revise and adopt new, and perhaps lower supply reliability criteria for integrated resource planning. More complex reliability criteria, such as energy related indices, which take into account the magnitude, frequency and duration of the expected interruptions are better adapted than the simpler capacity-based reliability criteria such as loss of load expectation. 7 refs., 5 figs., 10 tabs

Three-Dimensional Integrated Circuit (3D IC) Key Technology: Through-Silicon Via (TSV).

Science.gov (United States)

Shen, Wen-Wei; Chen, Kuan-Neng

2017-12-01

3D integration with through-silicon via (TSV) is a promising candidate to perform system-level integration with smaller package size, higher interconnection density, and better performance. TSV fabrication is the key technology to permit communications between various strata of the 3D integration system. TSV fabrication steps, such as etching, isolation, metallization processes, and related failure modes, as well as other characterizations are discussed in this invited review paper.

RULES FOR SELECTING AND USING KEY PERFORMANCE INDICATORS FOR THE SERVICE INDUSTRY

Directory of Open Access Journals (Sweden)

Alexandra - Elena RUSĂNEANU

2014-06-01

Full Text Available There is no question that performance is the desired result of every activity or action. In order to correctly measure an organization’s performance it is necessary to select key performance indicators (KPIs that will deliver long-term value to the company. KPIs are presenting performance information for all levels of the organization and they are reflecting the progress made so far to achieve strategic objectives. The selection of the key performance indicators must be made according to the organization’s industry and activity. The company must truly understand its business and its mission. Also, KPIs must be closely linked to the strategic objectives. The focus of this research is to present effective rules for defining key performance indicators for the Service industry. This sector of economy consists in generating intangible goods like experience, expertise and information. Therefore, monitoring this type of services requires a different approach when defining performance indicators compared to the manufacturing industry.

Selecting of key safety parameters in reactor nuclear safety supervision

International Nuclear Information System (INIS)

He Fan; Yu Hong

2014-01-01

The safety parameters indicate the operational states and safety of research reactor are the basis of nuclear safety supervision institution to carry out effective supervision to nuclear facilities. In this paper, the selecting of key safety parameters presented by the research reactor operating unit to National Nuclear Safety Administration that can express the research reactor operational states and safety when operational occurrence or nuclear accident happens, and the interrelationship between them are discussed. Analysis shows that, the key parameters to nuclear safety supervision of research reactor including design limits, operational limits and conditions, safety system settings, safety limits, acceptable limits and emergency action level etc. (authors)

Factors Influencing the Selection of the Systems Integration Organizational Model Type for Planning and Implementing Government High-Technology Programs

Science.gov (United States)

Thomas, Leann; Utley, Dawn

2006-01-01

While there has been extensive research in defining project organizational structures for traditional projects, little research exists to support high technology government project s organizational structure definition. High-Technology Government projects differ from traditional projects in that they are non-profit, span across Government-Industry organizations, typically require significant integration effort, and are strongly susceptible to a volatile external environment. Systems Integration implementation has been identified as a major contributor to both project success and failure. The literature research bridges program management organizational planning, systems integration, organizational theory, and independent project reports, in order to assess Systems Integration (SI) organizational structure selection for improving the high-technology government project s probability of success. This paper will describe the methodology used to 1) Identify and assess SI organizational structures and their success rate, and 2) Identify key factors to be used in the selection of these SI organizational structures during the acquisition strategy process.

Selective Integration in the Material-Point Method

DEFF Research Database (Denmark)

Andersen, Lars; Andersen, Søren; Damkilde, Lars

2009-01-01

The paper deals with stress integration in the material-point method. In order to avoid parasitic shear in bending, a formulation is proposed, based on selective integration in the background grid that is used to solve the governing equations. The suggested integration scheme is compared...... to a traditional material-point-method computation in which the stresses are evaluated at the material points. The deformation of a cantilever beam is analysed, assuming elastic or elastoplastic material behaviour....

Integration of quantum key distribution and private classical communication through continuous variable

Science.gov (United States)

Wang, Tianyi; Gong, Feng; Lu, Anjiang; Zhang, Damin; Zhang, Zhengping

2017-12-01

In this paper, we propose a scheme that integrates quantum key distribution and private classical communication via continuous variables. The integrated scheme employs both quadratures of a weak coherent state, with encrypted bits encoded on the signs and Gaussian random numbers encoded on the values of the quadratures. The integration enables quantum and classical data to share the same physical and logical channel. Simulation results based on practical system parameters demonstrate that both classical communication and quantum communication can be implemented over distance of tens of kilometers, thus providing a potential solution for simultaneous transmission of quantum communication and classical communication.

An integrated model for supplier selection process

Institute of Scientific and Technical Information of China (English)

无

2003-01-01

In today's highly competitive manufacturing environment, the supplier selection process becomes one of crucial activities in supply chain management. In order to select the best supplier(s) it is not only necessary to continuously tracking and benchmarking performance of suppliers but also to make a tradeoff between tangible and intangible factors some of which may conflict. In this paper an integration of case-based reasoning (CBR), analytical network process (ANP) and linear programming (LP) is proposed to solve the supplier selection problem.

Attentional selection in visual perception, memory and action: a quest for cross-domain integration.

Science.gov (United States)

Schneider, Werner X; Einhäuser, Wolfgang; Horstmann, Gernot

2013-10-19

For decades, the cognitive and neural sciences have benefitted greatly from a separation of mind and brain into distinct functional domains. The tremendous success of this approach notwithstanding, it is self-evident that such a view is incomplete. Goal-directed behaviour of an organism requires the joint functioning of perception, memory and sensorimotor control. A prime candidate for achieving integration across these functional domains are attentional processes. Consequently, this Theme Issue brings together studies of attentional selection from many fields, both experimental and theoretical, that are united in their quest to find overreaching integrative principles of attention between perception, memory and action. In all domains, attention is understood as combination of competition and priority control ('bias'), with the task as a decisive driving factor to ensure coherent goal-directed behaviour and cognition. Using vision as the predominant model system for attentional selection, many studies of this Theme Issue focus special emphasis on eye movements as a selection process that is both a fundamental action and serves a key function in perception. The Theme Issue spans a wide range of methods, from measuring human behaviour in the real word to recordings of single neurons in the non-human primate brain. We firmly believe that combining such a breadth in approaches is necessary not only for attentional selection, but also to take the next decisive step in all of the cognitive and neural sciences: to understand cognition and behaviour beyond isolated domains.

Attentional selection in visual perception, memory and action: a quest for cross-domain integration

Science.gov (United States)

Schneider, Werner X.; Einhäuser, Wolfgang; Horstmann, Gernot

2013-01-01

For decades, the cognitive and neural sciences have benefitted greatly from a separation of mind and brain into distinct functional domains. The tremendous success of this approach notwithstanding, it is self-evident that such a view is incomplete. Goal-directed behaviour of an organism requires the joint functioning of perception, memory and sensorimotor control. A prime candidate for achieving integration across these functional domains are attentional processes. Consequently, this Theme Issue brings together studies of attentional selection from many fields, both experimental and theoretical, that are united in their quest to find overreaching integrative principles of attention between perception, memory and action. In all domains, attention is understood as combination of competition and priority control (‘bias’), with the task as a decisive driving factor to ensure coherent goal-directed behaviour and cognition. Using vision as the predominant model system for attentional selection, many studies of this Theme Issue focus special emphasis on eye movements as a selection process that is both a fundamental action and serves a key function in perception. The Theme Issue spans a wide range of methods, from measuring human behaviour in the real word to recordings of single neurons in the non-human primate brain. We firmly believe that combining such a breadth in approaches is necessary not only for attentional selection, but also to take the next decisive step in all of the cognitive and neural sciences: to understand cognition and behaviour beyond isolated domains. PMID:24018715

Personnel Selection Influences on Remotely Piloted Aircraft Human-System Integration.

Science.gov (United States)

Carretta, Thomas R; King, Raymond E

2015-08-01

Human-system integration (HSI) is a complex process used to design and develop systems that integrate human capabilities and limitations in an effective and affordable manner. Effective HSI incorporates several domains, including manpower, personnel and training, human factors, environment, safety, occupational health, habitability, survivability, logistics, intelligence, mobility, and command and control. To achieve effective HSI, the relationships among these domains must be considered. Although this integrated approach is well documented, there are many instances where it is not followed. Human factors engineers typically focus on system design with little attention to the skills, abilities, and other characteristics needed by human operators. When problems with fielded systems occur, additional training of personnel is developed and conducted. Personnel selection is seldom considered during the HSI process. Complex systems such as aviation require careful selection of the individuals who will interact with the system. Personnel selection is a two-stage process involving select-in and select-out procedures. Select-in procedures determine which candidates have the aptitude to profit from training and represent the best investment. Select-out procedures focus on medical qualification and determine who should not enter training for medical reasons. The current paper discusses the role of personnel selection in the HSI process in the context of remotely piloted aircraft systems.

Self-transcendence: Lonergan's key to integration of nursing theory, research, and practice.

Science.gov (United States)

Perry, Donna J

2004-04-01

This paper proposes that the philosophy of Bernard Lonergan can provide insight into the challenge of integrating nursing theory, research and practice. The author discusses Lonergan's work in regard to reflective understanding, authenticity and the human person as a subject of consciously developing unity. This is followed by a discussion of two key elements in Lonergan's work that relate to nursing: the subject-object challenge of nursing inquiry and common sense vs. scientific knowledge. The author suggests that integration of nursing theory, science and practice may be achieved through self-transcendence.

Integrated vehicle-based safety systems light-vehicle field operational test key findings report.

Science.gov (United States)

2011-01-01

"This document presents key findings from the light-vehicle field operational test conducted as part of the Integrated Vehicle-Based Safety Systems program. These findings are the result of analyses performed by the University of Michigan Transportat...

Automating an integrated spatial data-mining model for landfill site selection

Science.gov (United States)

Abujayyab, Sohaib K. M.; Ahamad, Mohd Sanusi S.; Yahya, Ahmad Shukri; Ahmad, Siti Zubaidah; Aziz, Hamidi Abdul

2017-10-01

An integrated programming environment represents a robust approach to building a valid model for landfill site selection. One of the main challenges in the integrated model is the complicated processing and modelling due to the programming stages and several limitations. An automation process helps avoid the limitations and improve the interoperability between integrated programming environments. This work targets the automation of a spatial data-mining model for landfill site selection by integrating between spatial programming environment (Python-ArcGIS) and non-spatial environment (MATLAB). The model was constructed using neural networks and is divided into nine stages distributed between Matlab and Python-ArcGIS. A case study was taken from the north part of Peninsular Malaysia. 22 criteria were selected to utilise as input data and to build the training and testing datasets. The outcomes show a high-performance accuracy percentage of 98.2% in the testing dataset using 10-fold cross validation. The automated spatial data mining model provides a solid platform for decision makers to performing landfill site selection and planning operations on a regional scale.

Dataset of statements on policy integration of selected intergovernmental organizations

Directory of Open Access Journals (Sweden)

Jale Tosun

2018-04-01

Full Text Available This article describes data for 78 intergovernmental organizations (IGOs working on topics related to energy governance, environmental protection, and the economy. The number of IGOs covered also includes organizations active in other sectors. The point of departure for data construction was the Correlates of War dataset, from which we selected this sample of IGOs. We updated and expanded the empirical information on the IGOs selected by manual coding. Most importantly, we collected the primary law texts of the individual IGOs in order to code whether they commit themselves to environmental policy integration (EPI, climate policy integration (CPI and/or energy policy integration (EnPI.

Mining method selection by integrated AHP and PROMETHEE method.

Science.gov (United States)

Bogdanovic, Dejan; Nikolic, Djordje; Ilic, Ivana

2012-03-01

Selecting the best mining method among many alternatives is a multicriteria decision making problem. The aim of this paper is to demonstrate the implementation of an integrated approach that employs AHP and PROMETHEE together for selecting the most suitable mining method for the "Coka Marin" underground mine in Serbia. The related problem includes five possible mining methods and eleven criteria to evaluate them. Criteria are accurately chosen in order to cover the most important parameters that impact on the mining method selection, such as geological and geotechnical properties, economic parameters and geographical factors. The AHP is used to analyze the structure of the mining method selection problem and to determine weights of the criteria, and PROMETHEE method is used to obtain the final ranking and to make a sensitivity analysis by changing the weights. The results have shown that the proposed integrated method can be successfully used in solving mining engineering problems.

Theory-practice integration in selected clinical situations

Directory of Open Access Journals (Sweden)

M Davhana-Maselesele

2001-09-01

Full Text Available The current changes in health care systems challenge knowledgeable, mature and independent practitioners to integrate theoretical content with practice. The aim of this study was to investigate the problems of integrating theory with practice in selected clinical nursing situations. The study focused on rendering of family planning services to clients as a component of Community Nursing Science. Structured observation schedules were used to observe the theoretical content of the curriculum as well as the practical application of what has been taught in the clinical area. The findings of the study revealed that there was a need for an integrated holistic curriculum, which would address the needs of the community. It was concluded that a problem-based and community-based curriculum, intersectoral collaboration between college and hospital managements and student involvement in all processes of teaching and learning would improve the integration of theory and practice. There also appeared to be a need for tutors to be more involved in clinical teaching and accompaniment.

EUROPEAN INTEGRATION FROM POLAND’S VIEWPOINT. SELECTED ISSUES

OpenAIRE

Iwona M. Pawlas

2014-01-01

It has been ten years since Poland joined the European Union in May 2004. Integration with the EU structures resulted in considerable economic, social and political advantages. On the other hand membership in the EU created new challenges for Poland, the Polish companies and the Polish citizens. The paper reviews selected issues of Poland’s integration with the European Union with special focus on net financial effect of membership, competitiveness of Polish goods on single European market, p...

Integrated systems approach identifies risk regulatory pathways and key regulators in coronary artery disease.

Science.gov (United States)

Zhang, Yan; Liu, Dianming; Wang, Lihong; Wang, Shuyuan; Yu, Xuexin; Dai, Enyu; Liu, Xinyi; Luo, Shanshun; Jiang, Wei

2015-12-01

Coronary artery disease (CAD) is the most common type of heart disease. However, the molecular mechanisms of CAD remain elusive. Regulatory pathways are known to play crucial roles in many pathogenic processes. Thus, inferring risk regulatory pathways is an important step toward elucidating the mechanisms underlying CAD. With advances in high-throughput data, we developed an integrated systems approach to identify CAD risk regulatory pathways and key regulators. Firstly, a CAD-related core subnetwork was identified from a curated transcription factor (TF) and microRNA (miRNA) regulatory network based on a random walk algorithm. Secondly, candidate risk regulatory pathways were extracted from the subnetwork by applying a breadth-first search (BFS) algorithm. Then, risk regulatory pathways were prioritized based on multiple CAD-associated data sources. Finally, we also proposed a new measure to prioritize upstream regulators. We inferred that phosphatase and tensin homolog (PTEN) may be a key regulator in the dysregulation of risk regulatory pathways. This study takes a closer step than the identification of disease subnetworks or modules. From the risk regulatory pathways, we could understand the flow of regulatory information in the initiation and progression of the disease. Our approach helps to uncover its potential etiology. We developed an integrated systems approach to identify risk regulatory pathways. We proposed a new measure to prioritize the key regulators in CAD. PTEN may be a key regulator in dysregulation of the risk regulatory pathways.

Common-signal-induced synchronization in photonic integrated circuits and its application to secure key distribution.

Science.gov (United States)

Sasaki, Takuma; Kakesu, Izumi; Mitsui, Yusuke; Rontani, Damien; Uchida, Atsushi; Sunada, Satoshi; Yoshimura, Kazuyuki; Inubushi, Masanobu

2017-10-16

We experimentally achieve common-signal-induced synchronization in two photonic integrated circuits with short external cavities driven by a constant-amplitude random-phase light. The degree of synchronization can be controlled by changing the optical feedback phase of the two photonic integrated circuits. The change in the optical feedback phase leads to a significant redistribution of the spectral energy of optical and RF spectra, which is a unique characteristic of PICs with the short external cavity. The matching of the RF and optical spectra is necessary to achieve synchronization between the two PICs, and stable synchronization can be obtained over an hour in the presence of optical feedback. We succeed in generating information-theoretic secure keys and achieving the final key generation rate of 184 kb/s using the PICs.

Size-selective detection in integrated optical interferometric biosensors

NARCIS (Netherlands)

Mulder, Harmen K P; Ymeti, Aurel; Subramaniam, Vinod; Kanger, Johannes S

2012-01-01

We present a new size-selective detection method for integrated optical interferometric biosensors that can strongly enhance their performance. We demonstrate that by launching multiple wavelengths into a Young interferometer waveguide sensor it is feasible to derive refractive index changes from

Suggestions on selection of clay site as a key alternative of underground repository for HLW geological disposal in China

International Nuclear Information System (INIS)

Zheng Hualing; Fu Bingjun; Fan Xianhua; Chen Shi; Sun Donghui

2006-01-01

Site selection for the underground repository is a vital problem with respect to the HLW geological disposal. Over the past decades, we have been focusing our attention on granite as a priority in China. However, there are some problems have to be discussed on this matter. In this paper, both experiences gained and lessons learned in the international community regarding the site selection are described. And then, after analyzing a lot of some key factors affecting the site selection, some comments and suggestions on selection of clay site as a key alternative before final decision making in China are presented. (authors)

The effects of selective and divided attention on sensory precision and integration.

Science.gov (United States)

Odegaard, Brian; Wozny, David R; Shams, Ladan

2016-02-12

In our daily lives, our capacity to selectively attend to stimuli within or across sensory modalities enables enhanced perception of the surrounding world. While previous research on selective attention has studied this phenomenon extensively, two important questions still remain unanswered: (1) how selective attention to a single modality impacts sensory integration processes, and (2) the mechanism by which selective attention improves perception. We explored how selective attention impacts performance in both a spatial task and a temporal numerosity judgment task, and employed a Bayesian Causal Inference model to investigate the computational mechanism(s) impacted by selective attention. We report three findings: (1) in the spatial domain, selective attention improves precision of the visual sensory representations (which were relatively precise), but not the auditory sensory representations (which were fairly noisy); (2) in the temporal domain, selective attention improves the sensory precision in both modalities (both of which were fairly reliable to begin with); (3) in both tasks, selective attention did not exert a significant influence over the tendency to integrate sensory stimuli. Therefore, it may be postulated that a sensory modality must possess a certain inherent degree of encoding precision in order to benefit from selective attention. It also appears that in certain basic perceptual tasks, the tendency to integrate crossmodal signals does not depend significantly on selective attention. We conclude with a discussion of how these results relate to recent theoretical considerations of selective attention. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Selectable Hyperspectral Airborne Remote-sensing Kit (SHARK) on the Vision II turbine rotorcraft UAV over the Florida Keys

Science.gov (United States)

Holasek, R. E.; Nakanishi, K.; Swartz, B.; Zacaroli, R.; Hill, B.; Naungayan, J.; Herwitz, S.; Kavros, P.; English, D. C.

2013-12-01

As part of the NASA ROSES program, the NovaSol Selectable Hyperspectral Airborne Remote-sensing Kit (SHARK) was flown as the payload on the unmanned Vision II helicopter. The goal of the May 2013 data collection was to obtain high resolution visible and near-infrared (visNIR) hyperspectral data of seagrasses and coral reefs in the Florida Keys. The specifications of the SHARK hyperspectral system and the Vision II turbine rotorcraft will be described along with the process of integrating the payload to the vehicle platform. The minimal size, weight, and power (SWaP) specifications of the SHARK system is an ideal match to the Vision II helicopter and its flight parameters. One advantage of the helicopter over fixed wing platforms is its inherent ability to take off and land in a limited area and without a runway, enabling the UAV to be located in close proximity to the experiment areas and the science team. Decisions regarding integration times, waypoint selection, mission duration, and mission frequency are able to be based upon the local environmental conditions and can be modified just prior to take off. The operational procedures and coordination between the UAV pilot, payload operator, and scientist will be described. The SHARK system includes an inertial navigation system and digital elevation model (DEM) which allows image coordinates to be calculated onboard the aircraft in real-time. Examples of the geo-registered images from the data collection will be shown. SHARK mounted below VTUAV. SHARK deployed on VTUAV over water.

The Influence of Selective and Divided Attention on Audiovisual Integration in Children.

Science.gov (United States)

Yang, Weiping; Ren, Yanna; Yang, Dan Ou; Yuan, Xue; Wu, Jinglong

2016-01-24

This article aims to investigate whether there is a difference in audiovisual integration in school-aged children (aged 6 to 13 years; mean age = 9.9 years) between the selective attention condition and divided attention condition. We designed a visual and/or auditory detection task that included three blocks (divided attention, visual-selective attention, and auditory-selective attention). The results showed that the response to bimodal audiovisual stimuli was faster than to unimodal auditory or visual stimuli under both divided attention and auditory-selective attention conditions. However, in the visual-selective attention condition, no significant difference was found between the unimodal visual and bimodal audiovisual stimuli in response speed. Moreover, audiovisual behavioral facilitation effects were compared between divided attention and selective attention (auditory or visual attention). In doing so, we found that audiovisual behavioral facilitation was significantly difference between divided attention and selective attention. The results indicated that audiovisual integration was stronger in the divided attention condition than that in the selective attention condition in children. Our findings objectively support the notion that attention can modulate audiovisual integration in school-aged children. Our study might offer a new perspective for identifying children with conditions that are associated with sustained attention deficit, such as attention-deficit hyperactivity disorder. © The Author(s) 2016.

Integrating genomic selection into dairy cattle breeding programmes: a review.

Science.gov (United States)

Bouquet, A; Juga, J

2013-05-01

Extensive genetic progress has been achieved in dairy cattle populations on many traits of economic importance because of efficient breeding programmes. Success of these programmes has relied on progeny testing of the best young males to accurately assess their genetic merit and hence their potential for breeding. Over the last few years, the integration of dense genomic information into statistical tools used to make selection decisions, commonly referred to as genomic selection, has enabled gains in predicting accuracy of breeding values for young animals without own performance. The possibility to select animals at an early stage allows defining new breeding strategies aimed at boosting genetic progress while reducing costs. The first objective of this article was to review methods used to model and optimize breeding schemes integrating genomic selection and to discuss their relative advantages and limitations. The second objective was to summarize the main results and perspectives on the use of genomic selection in practical breeding schemes, on the basis of the example of dairy cattle populations. Two main designs of breeding programmes integrating genomic selection were studied in dairy cattle. Genomic selection can be used either for pre-selecting males to be progeny tested or for selecting males to be used as active sires in the population. The first option produces moderate genetic gains without changing the structure of breeding programmes. The second option leads to large genetic gains, up to double those of conventional schemes because of a major reduction in the mean generation interval, but it requires greater changes in breeding programme structure. The literature suggests that genomic selection becomes more attractive when it is coupled with embryo transfer technologies to further increase selection intensity on the dam-to-sire pathway. The use of genomic information also offers new opportunities to improve preservation of genetic variation. However

An integrated approach to site selection for nuclear power plants

International Nuclear Information System (INIS)

Hassan, E.M.A.

1975-01-01

A method of analysing and evaluating the large number of factors influencing site selection is proposed, which can interrelate these factors and associated problems in an integrated way and at the same time establish a technique for site evaluation. The objective is to develop an integrated programme that illustrates the complexity and dynamic interrelationships of the various factors to develop an improved understanding of the functions and objectives of siting nuclear power plants and would aim finally at the development of an effective procedure and technique for site evaluation and/or comparative evaluation for making rational site-selection decisions. (author)

Integrating Variable Renewable Energy into the Grid: Key Issues, Greening the Grid (Spanish Version)

Energy Technology Data Exchange (ETDEWEB)

2016-04-01

This is the Spanish version of 'Greening the Grid - Integrating Variable Renewable Energy into the Grid: Key Issues'. To foster sustainable, low-emission development, many countries are establishing ambitious renewable energy targets for their electricity supply. Because solar and wind tend to be more variable and uncertain than conventional sources, meeting these targets will involve changes to power system planning and operations. Grid integration is the practice of developing efficient ways to deliver variable renewable energy (VRE) to the grid. Good integration methods maximize the cost-effectiveness of incorporating VRE into the power system while maintaining or increasing system stability and reliability. When considering grid integration, policy makers, regulators, and system operators consider a variety of issues, which can be organized into four broad topics: New Renewable Energy Generation, New Transmission, Increased System Flexibility, and Planning for a High RE Future.

Control structure selection for energy integrated distillation column

DEFF Research Database (Denmark)

Hansen, J.E.; Jørgensen, Sten Bay

1998-01-01

This paper treats a case study on control structure selection for an almost binary distillation column. The column is energy integrated with a heat pump in order to transfer heat from the condenser to the reboiler. This integrated plant configuration renders the possible control structures somewhat...... different from what is usual for binary distillation columns. Further the heat pump enables disturbances to propagate faster through the system. The plant has six possible actuators of which three must be used to stabilize the system. Hereby three actuators are left for product purity control. An MILP...

Water management as a key component of integrated weed management

Directory of Open Access Journals (Sweden)

Antonio Berti

2010-09-01

Full Text Available Water management within the cropping system is a key factor for an integrated weed management. Soil moisture affects seed persistence and seed dormancy, thus influencing their germination, the establishment of seedlings as well as the competition at adult stage and the number, vitality and dormancy of the new seeds produced by the weeds. The interactions among water availability and competition are very complex and still not fully understood. A research effort in this sector should the be very relevant for the development of new approaches of weed management, such as “Ecological weed management”, aiming to reduce weed density and competitiveness and, in the medium term, to prevent undesired modifications of the weed flora.

LabKey Server: An open source platform for scientific data integration, analysis and collaboration

Science.gov (United States)

2011-01-01

Background Broad-based collaborations are becoming increasingly common among disease researchers. For example, the Global HIV Enterprise has united cross-disciplinary consortia to speed progress towards HIV vaccines through coordinated research across the boundaries of institutions, continents and specialties. New, end-to-end software tools for data and specimen management are necessary to achieve the ambitious goals of such alliances. These tools must enable researchers to organize and integrate heterogeneous data early in the discovery process, standardize processes, gain new insights into pooled data and collaborate securely. Results To meet these needs, we enhanced the LabKey Server platform, formerly known as CPAS. This freely available, open source software is maintained by professional engineers who use commercially proven practices for software development and maintenance. Recent enhancements support: (i) Submitting specimens requests across collaborating organizations (ii) Graphically defining new experimental data types, metadata and wizards for data collection (iii) Transitioning experimental results from a multiplicity of spreadsheets to custom tables in a shared database (iv) Securely organizing, integrating, analyzing, visualizing and sharing diverse data types, from clinical records to specimens to complex assays (v) Interacting dynamically with external data sources (vi) Tracking study participants and cohorts over time (vii) Developing custom interfaces using client libraries (viii) Authoring custom visualizations in a built-in R scripting environment. Diverse research organizations have adopted and adapted LabKey Server, including consortia within the Global HIV Enterprise. Atlas is an installation of LabKey Server that has been tailored to serve these consortia. It is in production use and demonstrates the core capabilities of LabKey Server. Atlas now has over 2,800 active user accounts originating from approximately 36 countries and 350

LabKey Server: An open source platform for scientific data integration, analysis and collaboration

Directory of Open Access Journals (Sweden)

Lum Karl

2011-03-01

Full Text Available Abstract Background Broad-based collaborations are becoming increasingly common among disease researchers. For example, the Global HIV Enterprise has united cross-disciplinary consortia to speed progress towards HIV vaccines through coordinated research across the boundaries of institutions, continents and specialties. New, end-to-end software tools for data and specimen management are necessary to achieve the ambitious goals of such alliances. These tools must enable researchers to organize and integrate heterogeneous data early in the discovery process, standardize processes, gain new insights into pooled data and collaborate securely. Results To meet these needs, we enhanced the LabKey Server platform, formerly known as CPAS. This freely available, open source software is maintained by professional engineers who use commercially proven practices for software development and maintenance. Recent enhancements support: (i Submitting specimens requests across collaborating organizations (ii Graphically defining new experimental data types, metadata and wizards for data collection (iii Transitioning experimental results from a multiplicity of spreadsheets to custom tables in a shared database (iv Securely organizing, integrating, analyzing, visualizing and sharing diverse data types, from clinical records to specimens to complex assays (v Interacting dynamically with external data sources (vi Tracking study participants and cohorts over time (vii Developing custom interfaces using client libraries (viii Authoring custom visualizations in a built-in R scripting environment. Diverse research organizations have adopted and adapted LabKey Server, including consortia within the Global HIV Enterprise. Atlas is an installation of LabKey Server that has been tailored to serve these consortia. It is in production use and demonstrates the core capabilities of LabKey Server. Atlas now has over 2,800 active user accounts originating from approximately 36

LabKey Server: an open source platform for scientific data integration, analysis and collaboration.

Science.gov (United States)

Nelson, Elizabeth K; Piehler, Britt; Eckels, Josh; Rauch, Adam; Bellew, Matthew; Hussey, Peter; Ramsay, Sarah; Nathe, Cory; Lum, Karl; Krouse, Kevin; Stearns, David; Connolly, Brian; Skillman, Tom; Igra, Mark

2011-03-09

Broad-based collaborations are becoming increasingly common among disease researchers. For example, the Global HIV Enterprise has united cross-disciplinary consortia to speed progress towards HIV vaccines through coordinated research across the boundaries of institutions, continents and specialties. New, end-to-end software tools for data and specimen management are necessary to achieve the ambitious goals of such alliances. These tools must enable researchers to organize and integrate heterogeneous data early in the discovery process, standardize processes, gain new insights into pooled data and collaborate securely. To meet these needs, we enhanced the LabKey Server platform, formerly known as CPAS. This freely available, open source software is maintained by professional engineers who use commercially proven practices for software development and maintenance. Recent enhancements support: (i) Submitting specimens requests across collaborating organizations (ii) Graphically defining new experimental data types, metadata and wizards for data collection (iii) Transitioning experimental results from a multiplicity of spreadsheets to custom tables in a shared database (iv) Securely organizing, integrating, analyzing, visualizing and sharing diverse data types, from clinical records to specimens to complex assays (v) Interacting dynamically with external data sources (vi) Tracking study participants and cohorts over time (vii) Developing custom interfaces using client libraries (viii) Authoring custom visualizations in a built-in R scripting environment. Diverse research organizations have adopted and adapted LabKey Server, including consortia within the Global HIV Enterprise. Atlas is an installation of LabKey Server that has been tailored to serve these consortia. It is in production use and demonstrates the core capabilities of LabKey Server. Atlas now has over 2,800 active user accounts originating from approximately 36 countries and 350 organizations. It tracks

Transceivers and receivers for quantum key distribution and methods pertaining thereto

Science.gov (United States)

DeRose, Christopher; Sarovar, Mohan; Soh, Daniel B.S.; Lentine, Anthony; Davids, Paul; Camacho, Ryan

2018-02-27

Various technologies for performing continuous-variable (CV) and discrete-variable (DV) quantum key distribution (QKD) with integrated electro-optical circuits are described herein. An integrated DV-QKD system uses Mach-Zehnder modulators to modulate a polarization of photons at a transmitter and select a photon polarization measurement basis at a receiver. An integrated CV-QKD system uses wavelength division multiplexing to send and receive amplitude-modulated and phase-modulated optical signals with a local oscillator signal while maintaining phase coherence between the modulated signals and the local oscillator signal.

Integrated model for supplier selection and performance evaluation

Directory of Open Access Journals (Sweden)

Borges de Araújo, Maria Creuza

2015-08-01

Full Text Available This paper puts forward a model for selecting suppliers and evaluating the performance of those already working with a company. A simulation was conducted in a food industry. This sector has high significance in the economy of Brazil. The model enables the phases of selecting and evaluating suppliers to be integrated. This is important so that a company can have partnerships with suppliers who are able to meet their needs. Additionally, a group method is used to enable managers who will be affected by this decision to take part in the selection stage. Finally, the classes resulting from the performance evaluation are shown to support the contractor in choosing the most appropriate relationship with its suppliers.

Integrated technology selection for energy conservation and PAHs control in iron and steel industry: Methodology and case study

International Nuclear Information System (INIS)

Li, Li; Lu, Yonglong; Shi, Yajuan; Wang, Tieyu; Luo, Wei; Gosens, Jorrit; Chen, Peng; Li, Haiqian

2013-01-01

Energy conservation and PAHs (polycyclic aromatic hydrocarbon) control are two challenges for the iron and steel industry, especially where the industry has developed at high speed. How to select appropriate technologies to improve energy efficiency and control pollution from PAHs simultaneously is encountered by both the researchers and the decision makers. This study sets up a framework on technology selection and combination which integrates technology assessment, multiple objective programming and scenario analysis. It can predict proper technology combination for different emission controls, energy conservation targets and desired levels of production. An iron and steel factory in Southwestern China is cited as a case. It is shown that stricter PAHs control will drive the transformation from process control technology to alternative smelting technology. In low PAHs limit, 25% energy reduction is a threshold. Before inclusion of a restraint on energy consumption at 25% reduction, PAHs emission is the key limiting factor for the technology selection; while after inclusion of this restraint, energy consumption becomes the key limiting factor. The desired level of production will also influence the technology selection. This study can help decision makers to select appropriate technologies to meet the PAHs control objectives and energy conservation strategies in energy-intensive industries. - Highlights: ► We predict technical strategy for energy and PAHs reduction in iron and steel mill. ► With low PAHs control objectives, process control technologies are preferable. ► With medium and high PAHs control goals, alternative smelting technology is dominate. ► In low PAHs control objective, 25% energy reduction is a threshold

Establishment of key grid-connected performance index system for integrated PV-ES system

Science.gov (United States)

Li, Q.; Yuan, X. D.; Qi, Q.; Liu, H. M.

2016-08-01

In order to further promote integrated optimization operation of distributed new energy/ energy storage/ active load, this paper studies the integrated photovoltaic-energy storage (PV-ES) system which is connected with the distribution network, and analyzes typical structure and configuration selection for integrated PV-ES generation system. By combining practical grid- connected characteristics requirements and technology standard specification of photovoltaic generation system, this paper takes full account of energy storage system, and then proposes several new grid-connected performance indexes such as paralleled current sharing characteristic, parallel response consistency, adjusting characteristic, virtual moment of inertia characteristic, on- grid/off-grid switch characteristic, and so on. A comprehensive and feasible grid-connected performance index system is then established to support grid-connected performance testing on integrated PV-ES system.

Practical use of the integrated reporting framework – an analysis of the content of integrated reports of selected companies

Directory of Open Access Journals (Sweden)

Monika Raulinajtys-Grzybek

2017-09-01

Full Text Available Practical use of the integrated reporting framework – an analysis of the content of integrated reports of selected companies The purpose of the article is to provide a research tool for an initial assessment of whether a company’s integrated reports meet the objectives set out in the IIRC Integrated Reporting Framework and its empirical verification. In particular, the research addresses whether the reports meet the goal of improving the quality of information available and covering all factors that influence the organization’s ability to create value. The article uses the theoretical output on the principles of preparing integrated reports and analyzes the content of selected integrated reports. Based on the source analysis, a research tool has been developed for an initial assessment of whether an integrated report fulfills its objectives. It consists of 42 questions that verify the coverage of the defined elements and the implementation of the guiding principles set by the IIRC. For empirical verification of the tool, a comparative analysis was carried out for reports prepared by selected companies operating in the utilities sector. Answering questions from the research tool allows a researcher to formulate conclusions about the implementation of the guiding principles and the completeness of the presentation of the content elements. As a result of the analysis of selected integrated reports, it was stated that various elements of the report are presented with different levels of accuracy in different reports. Reports provide the most complete information on performance and strategy. The information about business model and prospective data is in some cases presented without making a link to other parts of the report – e.g. risks and opportunities, financial data or capitals. The absence of such links limits the ability to claim that an integrated report meets its objectives, since a set of individual reports, each presenting

An Integrated DEMATEL-QFD Model for Medical Supplier Selection

OpenAIRE

Mehtap Dursun; Zeynep Şener

2014-01-01

Supplier selection is considered as one of the most critical issues encountered by operations and purchasing managers to sharpen the company’s competitive advantage. In this paper, a novel fuzzy multi-criteria group decision making approach integrating quality function deployment (QFD) and decision making trial and evaluation laboratory (DEMATEL) method is proposed for supplier selection. The proposed methodology enables to consider the impacts of inner dependence among supplier assessment cr...

Retroviral DNA integration: viral and cellular determinants of target-site selection.

Directory of Open Access Journals (Sweden)

Mary K Lewinski

2006-06-01

Full Text Available Retroviruses differ in their preferences for sites for viral DNA integration in the chromosomes of infected cells. Human immunodeficiency virus (HIV integrates preferentially within active transcription units, whereas murine leukemia virus (MLV integrates preferentially near transcription start sites and CpG islands. We investigated the viral determinants of integration-site selection using HIV chimeras with MLV genes substituted for their HIV counterparts. We found that transferring the MLV integrase (IN coding region into HIV (to make HIVmIN caused the hybrid to integrate with a specificity close to that of MLV. Addition of MLV gag (to make HIVmGagmIN further increased the similarity of target-site selection to that of MLV. A chimeric virus with MLV Gag only (HIVmGag displayed targeting preferences different from that of both HIV and MLV, further implicating Gag proteins in targeting as well as IN. We also report a genome-wide analysis indicating that MLV, but not HIV, favors integration near DNase I-hypersensitive sites (i.e., +/- 1 kb, and that HIVmIN and HIVmGagmIN also favored integration near these features. These findings reveal that IN is the principal viral determinant of integration specificity; they also reveal a new role for Gag-derived proteins, and strengthen models for integration targeting based on tethering of viral IN proteins to host proteins.

Integrating climate change adaptation in energy planning and decision-making - Key challenges and opportunities

DEFF Research Database (Denmark)

Olhoff, Anne; Olsen, Karen Holm

2011-01-01

management framework is used as the basis for identifying key challenges and opportunities to enhance the integration of climate change adaptation in energy planning and decision-making. Given its importance for raising awareness and for stimulating action by planners and decision-makers, emphasis is placed......Energy systems are significantly vulnerable to current climate variability and extreme events. As climate change becomes more pronounced, the risks and vulnerabilities will be exacerbated. To date, energy sector adaptation issues have received very limited attention. In this paper, a climate risk...... barriers to integration of climate risks and adaptive responses in energy planning and decision making. Both detailed assessments of the costs and benefits of integrating adaptation measures and rougher ‘order of magnitude’ estimates would enhance awareness raising and momentum for action....

Aging, selective attention, and feature integration.

Science.gov (United States)

Plude, D J; Doussard-Roosevelt, J A

1989-03-01

This study used feature-integration theory as a means of determining the point in processing at which selective attention deficits originate. The theory posits an initial stage of processing in which features are registered in parallel and then a serial process in which features are conjoined to form complex stimuli. Performance of young and older adults on feature versus conjunction search is compared. Analyses of reaction times and error rates suggest that elderly adults in addition to young adults, can capitalize on the early parallel processing stage of visual information processing, and that age decrements in visual search arise as a result of the later, serial stage of processing. Analyses of a third, unconfounded, conjunction search condition reveal qualitatively similar modes of conjunction search in young and older adults. The contribution of age-related data limitations is found to be secondary to the contribution of age decrements in selective attention.

A secure effective dynamic group password-based authenticated key agreement scheme for the integrated EPR information system

Directory of Open Access Journals (Sweden)

Vanga Odelu

2016-01-01

Full Text Available With the rapid growth of the Internet, a lot of electronic patient records (EPRs have been developed for e-medicine systems. The security and privacy issues of EPRs are important for the patients in order to understand how the hospitals control the use of their personal information, such as name, address, e-mail, medical records, etc. of a particular patient. Recently, Lee et al. proposed a simple group password-based authenticated key agreement protocol for the integrated EPR information system (SGPAKE. However, in this paper, we show that Lee et al.’s protocol is vulnerable to the off-line weak password guessing attack and as a result, their scheme does not provide users’ privacy. To withstand this security weakness found in Lee et al.’s scheme, we aim to propose an effective dynamic group password-based authenticated key exchange scheme for the integrated EPR information system, which retains the original merits of Lee et al.’s scheme. Through the informal and formal security analysis, we show that our scheme provides users’ privacy, perfect forward security and known-key security, and also protects online and offline password guessing attacks. Furthermore, our scheme efficiently supports the dynamic group password-based authenticated key agreement for the integrated EPR information system. In addition, we simulate our scheme for the formal security verification using the widely-accepted AVISPA (Automated Validation of Internet Security Protocols and Applications tool and show that our scheme is secure against passive and active attacks.

An integrated approach towards future ballistic neck protection materials selection.

Science.gov (United States)

Breeze, John; Helliker, Mark; Carr, Debra J

2013-05-01

Ballistic protection for the neck has historically taken the form of collars attached to the ballistic vest (removable or fixed), but other approaches, including the development of prototypes incorporating ballistic material into the collar of an under body armour shirt, are now being investigated. Current neck collars incorporate the same ballistic protective fabrics as the soft armour of the remaining vest, reflecting how ballistic protective performance alone has historically been perceived as the most important property for neck protection. However, the neck has fundamental differences from the thorax in terms of anatomical vulnerability, flexibility and equipment integration, necessitating a separate solution from the thorax in terms of optimal materials selection. An integrated approach towards the selection of the most appropriate combination of materials to be used for each of the two potential designs of future neck protection has been developed. This approach requires evaluation of the properties of each potential material in addition to ballistic performance alone, including flexibility, mass, wear resistance and thermal burden. The aim of this article is to provide readers with an overview of this integrated approach towards ballistic materials selection and an update of its current progress in the development of future ballistic neck protection.

Integral criterion for selecting nonlinear crystals for frequency conversion

International Nuclear Information System (INIS)

Grechin, Sergei G

2009-01-01

An integral criterion, which takes into account all parameters determining the conversion efficiency, is offered for selecting nonlinear crystals for frequency conversion. The angular phase-matching width is shown to be related to the beam walk-off angle. (nonlinear optical phenomena)

Technique for selection of transient radiation-hard junction-isolated integrated circuits

International Nuclear Information System (INIS)

Crowley, J.L.; Junga, F.A.; Stultz, T.J.

1976-01-01

A technique is presented which demonstrates the feasibility of selecting junction-isolated integrated circuits (JI/ICS) for use in transient radiation environments. The procedure guarantees that all PNPN paths within the integrated circuit are identified and describes the methods used to determine whether the paths represent latchup susceptible structures. Two examples of the latchup analysis are given involving an SSI and an LSI bipolar junction-isolated integrated circuit

Performance characteristics of selected integrating ion chambers

International Nuclear Information System (INIS)

Lubenau, J.O.; Liberace, R.

1977-01-01

Certain types of integrating ion chambers have been identified as acceptable equipment for a nationwide medical X-ray exposure survey program. In this study, Victoreen 2.5, 5 and 10 R condenser R-chambers, the Victoreen 666 Diagnostic Probe (used in the integrating mode) and the Bendix 200 mR and 5 R low energy dosimeters were evaluated for recombination losses and for energy dependence. Recombination losses were determined for exposure rates ranging from 0.3 to 80 R/sec. Energy dependence was determined for X-ray beam qualities ranging from 45 kVp and 0.83 mm Al first half value layer to 125 kVp and 4.8 mm Al first half value layer. The data enable selection of instruments so that errors from recombination losses and energy dependence can be minimized. (author)

A semi-automatic 2D-to-3D video conversion with adaptive key-frame selection

Science.gov (United States)

Ju, Kuanyu; Xiong, Hongkai

2014-11-01

To compensate the deficit of 3D content, 2D to 3D video conversion (2D-to-3D) has recently attracted more attention from both industrial and academic communities. The semi-automatic 2D-to-3D conversion which estimates corresponding depth of non-key-frames through key-frames is more desirable owing to its advantage of balancing labor cost and 3D effects. The location of key-frames plays a role on quality of depth propagation. This paper proposes a semi-automatic 2D-to-3D scheme with adaptive key-frame selection to keep temporal continuity more reliable and reduce the depth propagation errors caused by occlusion. The potential key-frames would be localized in terms of clustered color variation and motion intensity. The distance of key-frame interval is also taken into account to keep the accumulated propagation errors under control and guarantee minimal user interaction. Once their depth maps are aligned with user interaction, the non-key-frames depth maps would be automatically propagated by shifted bilateral filtering. Considering that depth of objects may change due to the objects motion or camera zoom in/out effect, a bi-directional depth propagation scheme is adopted where a non-key frame is interpolated from two adjacent key frames. The experimental results show that the proposed scheme has better performance than existing 2D-to-3D scheme with fixed key-frame interval.

Temperature Characteristics of Monolithically Integrated Wavelength-Selectable Light Sources

International Nuclear Information System (INIS)

Han Liang-Shun; Zhu Hong-Liang; Zhang Can; Ma Li; Liang Song; Wang Wei

2013-01-01

The temperature characteristics of monolithically integrated wavelength-selectable light sources are experimentally investigated. The wavelength-selectable light sources consist of four distributed feedback (DFB) lasers, a multimode interferometer coupler, and a semiconductor optical amplifier. The oscillating wavelength of the DFB laser could be modulated by adjusting the device operating temperature. A wavelength range covering over 8.0nm is obtained with stable single-mode operation by selecting the appropriate laser and chip temperature. The thermal crosstalk caused by the lateral heat spreading between lasers operating simultaneously is evaluated by oscillating-wavelength shift. The thermal crosstalk approximately decreases exponentially as the increasing distance between lasers

Integration: Dirty Word or Golden Key?

Science.gov (United States)

Kerry, Trevor

2007-01-01

This article examines the notion of integrated studies as a way of organising curriculum in schools. Drawing on the insights of educational philosophy, curriculum theory and learning theory it establishes the soundness of a theoretical case for integration. It examines what this view means for the art and science of teaching, and notes examples of…

Spatial attention enhances the selective integration of activity from area MT.

Science.gov (United States)

Masse, Nicolas Y; Herrington, Todd M; Cook, Erik P

2012-09-01

Distinguishing which of the many proposed neural mechanisms of spatial attention actually underlies behavioral improvements in visually guided tasks has been difficult. One attractive hypothesis is that attention allows downstream neural circuits to selectively integrate responses from the most informative sensory neurons. This would allow behavioral performance to be based on the highest-quality signals available in visual cortex. We examined this hypothesis by asking how spatial attention affects both the stimulus sensitivity of middle temporal (MT) neurons and their corresponding correlation with behavior. Analyzing a data set pooled from two experiments involving four monkeys, we found that spatial attention did not appreciably affect either the stimulus sensitivity of the neurons or the correlation between their activity and behavior. However, for those sessions in which there was a robust behavioral effect of attention, focusing attention inside the neuron's receptive field significantly increased the correlation between these two metrics, an indication of selective integration. These results suggest that, similar to mechanisms proposed for the neural basis of perceptual learning, the behavioral benefits of focusing spatial attention are attributable to selective integration of neural activity from visual cortical areas by their downstream targets.

Integration of diagnostics into the ITER machine

International Nuclear Information System (INIS)

Janeschitz, G.; Walker, C.; Costley, A.

2001-01-01

This paper defines and discusses the integration of diagnostics systems into the ITER machine. For each machine region, the key constraints and solutions adopted are discussed, and illustrated with selected examples. (author)

Key issues on safety design basis selection and safety assessment

International Nuclear Information System (INIS)

An, S.; Togo, Y.

1976-01-01

In current fast reactor design in Japan, four design accident conditions and four design seismic conditions are adopted as the design base classifications. These are classified by the considerations on both likelihood of occurrence and the severeness of the consequences. There are several major problem areas in safety design consideration such as core accident problems which include fuel sodium interaction, fuel failure propagation and residual decay heat removal, and decay heat removal systems problems which is more or less the problem of selection of appropriate system and of assurance of high reliability of the system. In view of licensing, two kinds of accidents are postulated in evaluating the adequacy of a reactor site. The one is the ''major accident'' which is the accident to give most severe radiation hazard to the public from technical point of view. The other is the ''hypothetical accident'', induced public accident of which is severer than that of major accident. While the concept of the former is rather unique to Japanese licensing, the latter is almost equivalent to design base hypothetical accident of the US practice. In this paper, design bases selections, key safety issues and some of the licensing considerations in Japan are described

Towards Integrated Health Technology Assessment for Improving Decision Making in Selected Countries.

Science.gov (United States)

Oortwijn, Wija; Determann, Domino; Schiffers, Krijn; Tan, Siok Swan; van der Tuin, Jeroen

2017-09-01

To assess the level of comprehensiveness of health technology assessment (HTA) practices around the globe and to formulate recommendations for enhancing legitimacy and fairness of related decision-making processes. To identify best practices, we developed an evaluation framework consisting of 13 criteria on the basis of the INTEGRATE-HTA model (integrative perspective on assessing health technologies) and the Accountability for Reasonableness framework (deliberative appraisal process). We examined different HTA systems in middle-income countries (Argentina, Brazil, and Thailand) and high-income countries (Australia, Canada, England, France, Germany, Scotland, and South Korea). For this purpose, desk research and structured interviews with relevant key stakeholders (N = 32) in the selected countries were conducted. HTA systems in Canada, England, and Scotland appear relatively well aligned with our framework, followed by Australia, Germany, and France. Argentina and South Korea are at an early stage, whereas Brazil and Thailand are at an intermediate level. Both desk research and interviews revealed that scoping is often not part of the HTA process. In contrast, providing evidence reports for assessment is well established. Indirect and unintended outcomes are increasingly considered, but there is room for improvement. Monitoring and evaluation of the HTA process is not well established across countries. Finally, adopting transparent and robust processes, including stakeholder consultation, takes time. This study presents a framework for assessing the level of comprehensiveness of the HTA process in a country. On the basis of applying the framework, we formulate recommendations on how the HTA community can move toward a more integrated decision-making process using HTA. Copyright © 2017 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

Analysis on working pressure selection of ACME integral test facility

International Nuclear Information System (INIS)

Chen Lian; Chang Huajian; Li Yuquan; Ye Zishen; Qin Benke

2011-01-01

An integral effects test facility, advanced core cooling mechanism experiment facility (ACME) was designed to verify the performance of the passive safety system and validate its safety analysis codes of a pressurized water reactor power plant. Three test facilities for AP1000 design were introduced and review was given. The problems resulted from the different working pressures of its test facilities were analyzed. Then a detailed description was presented on the working pressure selection of ACME facility as well as its characteristics. And the approach of establishing desired testing initial condition was discussed. The selected 9.3 MPa working pressure covered almost all important passive safety system enables the ACME to simulate the LOCAs with the same pressure and property similitude as the prototype. It's expected that the ACME design would be an advanced core cooling integral test facility design. (authors)

KPI (KEY PERFORMANCE INDICATORS APPLICATION ON BALLAST WATER TREATMENT SYSTEM SELECTION

Directory of Open Access Journals (Sweden)

Gülçin Vural

2017-01-01

Full Text Available Every day, more than 7,000 different marine species are transferred to different ecosystems via ballast water in ships. The introduction of invasive species can cause problems for native species. After realizing the serious potential problems associated with the transport of organisms in ballast water, national and international regulations were developed. In 2004, the International Maritime Organization introduced the International Convention for the Control and Management of Ships' Ballast Water and Sediments. With these regulations, the problems caused by ballast water have attracted attention and many companies have started to research and develop technologies for the management of ballast water. Today, there are hundreds of different systems for ballast-water treatment, and the selection of the most suitable system for a specific vessel is an increasingly important issue as the Convention nears enforcement on September 8, 2017. The goal of this study is to demonstrate that the application of key performance indicators (KPIs to the selection of a ballast-water treatment system (BWTS leads to a very useful tool with which shipyards can compare BWTSs. This allows them to make better choices and to designate the most suitable system for each of their ships. In this study, we examine two types of vessel from a shipyard in Istanbul, Turkey. They have different ballast-water capacities and equipment, and the most suitable system for each is selected by using the KPI method.

An integrated MCDM approach to green supplier selection

Directory of Open Access Journals (Sweden)

Morteza Yazdani

2014-06-01

Full Text Available Supplier selection management has been considered as an important subject for industrial organizations. In order to remain on the market, to gain profitability and to retain competitive advantage, business units need to establish an integrated and structured supplier selection system. In addition, environmental protection problems have been big solicitudes for organizations to consider green approach in supplier selection problem. However, finding proper suppliers involves several variables and it is critically a complex process. In this paper, the main attention is focused on finding the right supplier based on fuzzy multi criteria decision making (MCDM process. The weights of criteria are calculated by analytical hierarchical process (AHP and the final ranking is achieved by fuzzy technique for order preference by similarity to an ideal solution (TOPSIS. TOPSIS advantage among the other similar methods is to obtain the best solution close to ideal solution. The paper attempts to express better understanding by an example of an automobile manufacturing supply chain.

Multicriteria decision methodology for selecting technical alternatives in the Mixed Waste Integrated Program

International Nuclear Information System (INIS)

Ferrada, J.J.; Berry, J.B.

1993-11-01

The US Department of Energy (DOE) Mixed Waste Integrated Program (MWIP) has as one of its tasks the identification of a decision methodology and key decision criteria for the selection methodology. The aim of a multicriteria analysis is to provide an instrument for a systematic evaluation of distinct alternative projects. Determination of this methodology will clarify (1) the factors used to evaluate these alternatives, (2) the evaluator's view of the importance of the factors, and (3) the relative value of each alternative. The selected methodology must consider the Comprehensive Environmental Response Compensation and Liability Act (CERCLA) decision-making criteria for application to the analysis technology subsystems developed by the DOE Office of Technology Development. This report contains a compilation of several decision methodologies developed in various national laboratories, institutions, and universities. The purpose of these methodologies may vary, but the core of the decision attributes are very similar. Six approaches were briefly analyzed; from these six, in addition to recommendations made by the MWIP technical support group leaders and CERCLA, the final decision methodology was extracted. Slight variations are observed in the many methodologies developed by different groups, but most of the analyzed methodologies address similar aspects for the most part. These common aspects were the core of the methodology suggested in this report for use within MWIP for the selection of technologies. The set of criteria compiled and developed for this report have been grouped in five categories: (1) process effectiveness, (2) developmental status, (3) life-cycle cost, (4) implementability, and (5) regulatory compliance

Passive sampling of selected endocrine disrupting compounds using polar organic chemical integrative samplers

International Nuclear Information System (INIS)

Arditsoglou, Anastasia; Voutsa, Dimitra

2008-01-01

Two types of polar organic chemical integrative samplers (pharmaceutical POCIS and pesticide POCIS) were examined for their sampling efficiency of selected endocrine disrupting compounds (EDCs). Laboratory-based calibration of POCISs was conducted by exposing them at high and low concentrations of 14 EDCs (4-alkyl-phenols, their ethoxylate oligomers, bisphenol A, selected estrogens and synthetic steroids) for different time periods. The kinetic studies showed an integrative uptake up to 28 days. The sampling rates for the individual compounds were obtained. The use of POCISs could result in an integrative approach to the quality status of the aquatic systems especially in the case of high variation of water concentrations of EDCs. The sampling efficiency of POCISs under various field conditions was assessed after their deployment in different aquatic environments. - Calibration and field performance of polar organic integrative samplers for monitoring EDCs in aquatic environments

Integrative analysis to select cancer candidate biomarkers to targeted validation

Science.gov (United States)

Heberle, Henry; Domingues, Romênia R.; Granato, Daniela C.; Yokoo, Sami; Canevarolo, Rafael R.; Winck, Flavia V.; Ribeiro, Ana Carolina P.; Brandão, Thaís Bianca; Filgueiras, Paulo R.; Cruz, Karen S. P.; Barbuto, José Alexandre; Poppi, Ronei J.; Minghim, Rosane; Telles, Guilherme P.; Fonseca, Felipe Paiva; Fox, Jay W.; Santos-Silva, Alan R.; Coletta, Ricardo D.; Sherman, Nicholas E.; Paes Leme, Adriana F.

2015-01-01

Targeted proteomics has flourished as the method of choice for prospecting for and validating potential candidate biomarkers in many diseases. However, challenges still remain due to the lack of standardized routines that can prioritize a limited number of proteins to be further validated in human samples. To help researchers identify candidate biomarkers that best characterize their samples under study, a well-designed integrative analysis pipeline, comprising MS-based discovery, feature selection methods, clustering techniques, bioinformatic analyses and targeted approaches was performed using discovery-based proteomic data from the secretomes of three classes of human cell lines (carcinoma, melanoma and non-cancerous). Three feature selection algorithms, namely, Beta-binomial, Nearest Shrunken Centroids (NSC), and Support Vector Machine-Recursive Features Elimination (SVM-RFE), indicated a panel of 137 candidate biomarkers for carcinoma and 271 for melanoma, which were differentially abundant between the tumor classes. We further tested the strength of the pipeline in selecting candidate biomarkers by immunoblotting, human tissue microarrays, label-free targeted MS and functional experiments. In conclusion, the proposed integrative analysis was able to pre-qualify and prioritize candidate biomarkers from discovery-based proteomics to targeted MS. PMID:26540631

Performance of WLAN RSS-based SON for LTE/WLAN access network selection

NARCIS (Netherlands)

Wang, Y.; Djapic, R.; Bergström, A.; Kovács, I.Z.; Laselva, D.; Spaey, K.; Sas, B.

2014-01-01

Mobile Network Operators (MNOs) are integrating carrier-grade Wireless Local Area Network (WLAN) to cellular networks to improve network performance and user experience. Access network selection (ANS) between cellular and WLAN plays a key role in the integration. Given the complexity of

Public Key-Based Need-to-Know Authorization Engine Final Report CRADA No. TSB-1553-98

Energy Technology Data Exchange (ETDEWEB)

Mark, R. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Williams, R. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2017-11-01

The goals of this project were to develop a public key-based authentication service plug-in based on LLNL's requirements, integrate the public key-based authentication with the Intra Verse authorization service adn the LLNL NTK server by developing a full-featured version of the prototyped Intra Verse need-to-know plug in; and to test the authorization and need-to-know plug-in in a secured extranet prototype among selected national Labs.

Application of integrated QFD and fuzzy AHP approach in selection of suppliers

Directory of Open Access Journals (Sweden)

Bojana Jovanović

2014-10-01

Full Text Available Supplier selection is a widely considered issue in the field of management, especially in quality management. In this paper, in the selection of suppliers of electronic components we used the integrated QFD and fuzzy AHP approaches. The QFD method is used as a tool for translating stakeholder needs into evaluating criteria for suppliers. The fuzzy AHP approach is used as a tool for prioritizing stakeholders, stakeholders’ requirements, evaluating criteria and, finally, for prioritizing suppliers. The paper showcases a case study of implementation of the integrated QFD and fuzzy AHP approaches in the selection of the electronic components supplier in one Serbian company that produces electronic devices. Also presented is the algorithm of implementation of the proposed approach. To the best of our knowledge, this is the first implementation of the proposed approach in a Serbian company.

Data integration reveals key homeostatic mechanisms following low dose radiation exposure

Energy Technology Data Exchange (ETDEWEB)

Tilton, Susan C.; Matzke, Melissa M. [Computational Biology and Bioinformatics, Pacific Northwest National Laboratory, Richland, WA 99338 (United States); Sowa, Marianne B.; Stenoien, David L.; Weber, Thomas J. [Health Impacts and Exposure Science, Pacific Northwest National Laboratory, Richland, WA 99338 (United States); Morgan, William F. [Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA 99338 (United States); Waters, Katrina M., E-mail: katrina.waters@pnnl.gov [Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA 99338 (United States)

2015-05-15

The goal of this study was to define pathways regulated by low dose radiation to understand how biological systems respond to subtle perturbations in their environment and prioritize pathways for human health assessment. Using an in vitro 3-D human full thickness skin model, we have examined the temporal response of dermal and epidermal layers to 10 cGy X-ray using transcriptomic, proteomic, phosphoproteomic and metabolomic platforms. Bioinformatics analysis of each dataset independently revealed potential signaling mechanisms affected by low dose radiation, and integrating data shed additional insight into the mechanisms regulating low dose responses in human tissue. We examined direct interactions among datasets (top down approach) and defined several hubs as significant regulators, including transcription factors (YY1, MYC and CREB1), kinases (CDK2, PLK1) and a protease (MMP2). These data indicate a shift in response across time — with an increase in DNA repair, tissue remodeling and repression of cell proliferation acutely (24–72 h). Pathway-based integration (bottom up approach) identified common molecular and pathway responses to low dose radiation, including oxidative stress, nitric oxide signaling and transcriptional regulation through the SP1 factor that would not have been identified by the individual data sets. Significant regulation of key downstream metabolites of nitrative stress was measured within these pathways. Among the features identified in our study, the regulation of MMP2 and SP1 was experimentally validated. Our results demonstrate the advantage of data integration to broadly define the pathways and networks that represent the mechanisms by which complex biological systems respond to perturbation. - Highlights: • Low dose ionizing radiation altered homeostasis in 3D skin tissue model. • Global gene/protein/metabolite data integrated using complementary statistical approaches • Time and location-specific change in matrix regulation

Development of a seaweed species-selection index for successful culture in a seaweed-based integrated aquaculture system

Science.gov (United States)

Kang, Yun Hee; Hwang, Jae Ran; Chung, Ik Kyo; Park, Sang Rul

2013-03-01

Integrated multi-trophic aquaculture (IMTA) has been proposed as a concept that combines the cultivation of fed aquaculture species ( e.g., finfish/shrimp) with extractive aquaculture species ( e.g., shellfish/seaweed). In seaweed-based integrated aquaculture, seaweeds have the capacity to reduce the environmental impact of nitrogen-rich effluents on coastal ecosystems. Thus, selection of optimal species for such aquaculture is of great importance. The present study aimed to develop a seaweed species-selection index for selecting suitable species in seaweed-based integrated aquaculture system. The index was synthesized using available literature-based information, reference data, and physiological seaweed experiments to identify and prioritize the desired species. Undaria pinnatifida, Porphyra yezoensis and Ulva compressa scored the highest according to a seaweed-based integrated aquaculture suitability index (SASI). Seaweed species with the highest scores were adjudged to fit the integrated aquaculture systems. Despite the application of this model limited by local aquaculture environment, it is considered to be a useful tool for selecting seaweed species in IMTA.

Factors influencing subject selection in upper secondary education (Key Stage 4 for males and females in England

Directory of Open Access Journals (Sweden)

Joanne Vaughan

2015-08-01

Full Text Available Background Research to date has investigated the potential factors that influence students’ decisions in opting to study certain subjects during their upper secondary education. Trends in subject selection at this level (Key Stage 4 have been maintained over time and have consistently displayed comparable differences for males and females. It is recognised that males typically opt for subjects such as physical education and science, while females are traditionally noted as favouring the arts and humanities. These educational decisions may impact on future occupational directions. In light of recent initiatives, such as the English Baccalaureate, it is of interest to explore whether such measures have had an influence on this noted gender gap. Participants and procedure The present study investigates the potential predictors of subject selection, while controlling for gender, offering a specific focus on the education system in England. Attention is given to students’ perceived academic ability and attitude toward school, and how such factors may guide subject choice. Participants (N = 276 were students currently in the process of selecting optional modules for Key Stage 4 study. Results The findings demonstrate that female students are less likely than their male counterparts to opt for physical education (PE and business studies/information and communication technology (ICT as preferred modules, in comparison to ‘creative and performance’ subjects (reference category. Higher levels of reported masculinity were also shown to relate to the up-take of PE at Key Stage 4. Conclusions The implications of these findings are discussed in relation to existing research and practical contributions to the educational arena.

A case on vendor selection methodology: An integrated approach

Directory of Open Access Journals (Sweden)

Nikhil C. Shil

2009-11-01

Full Text Available Vendor selection methodology is a highly researched area in supply chain management l terature and a very significant decision taken by supply chain managers due to technological advances in the manufacturing process. Such research has two basic dimensions: one is related to the identification of variables affecting the performance of the vendors and the other deals with the methodology to be applied. Most of the research conducted in this area deal with the upfront selection of vendors. However, it is very common to have a list of dedicated vendors due to the development of sophisticated production technologies like just in time (JIT, a lean or agile manufacturing process where continuous flow of materials is a requirement. This paper addresses the issue of selecting the optimal vendor from the internal database of a company. Factor analysis, analytical hierarchy process and regression analysis is used in an integrated way to supplement the vendor selection process. The methodology presented here is simply a proposal where every possible room for adjustment is available.

Short-term selective alleviation of glucotoxicity and lipotoxicity ameliorates the suppressed expression of key β-cell factors under diabetic conditions

Energy Technology Data Exchange (ETDEWEB)

Shimo, Naoki [Department of Metabolic Medicine, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871 (Japan); Matsuoka, Taka-aki, E-mail: matsuoka@endmet.med.osaka-u.ac.jp [Department of Metabolic Medicine, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871 (Japan); Miyatsuka, Takeshi [Department of Metabolic Medicine, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871 (Japan); Department of Metabolism and Endocrinology, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Bunky-ku, Tokyo, 113-8421 (Japan); Takebe, Satomi; Tochino, Yoshihiro; Takahara, Mitsuyoshi [Department of Metabolic Medicine, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871 (Japan); Kaneto, Hideaki [Division of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, 577 Matsushima, Kurashiki-city, Okayama, 701-0192 (Japan); Shimomura, Iichiro [Department of Metabolic Medicine, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871 (Japan)

2015-11-27

Alleviation of hyperglycaemia and hyperlipidemia improves pancreatic β-cell function in type 2 diabetes. However, the underlying molecular mechanisms are still not well clarified. In this study, we aimed to elucidate how the expression alterations of key β-cell factors are altered by the short-term selective alleviation of glucotoxicity or lipotoxicity. We treated db/db mice for one week with empagliflozin and/or bezafibrate to alleviate glucotoxicity and/or liptotoxicity, respectively. The gene expression levels of Pdx1 and Mafa, and their potential targets, insulin 1, Slc2a2, and Glp1r, were higher in the islets of empagliflozin-treated mice, and levels of insulin 2 were higher in mice treated with both reagents, than in untreated mice. Moreover, compared to the pretreatment levels, Mafa and insulin 1 expression increased in empagliflozin-treated mice, and Slc2a2 increased in combination-treated mice. In addition, empagliflozin treatment enhanced β-cell proliferation assessed by Ki-67 immunostaining. Our date clearly demonstrated that the one-week selective alleviation of glucotoxicity led to the better expression levels of the key β-cell factors critical for β-cell function over pretreatment levels, and that the alleviation of lipotoxicity along with glucotoxicity augmented the favorable effects under diabetic conditions. - Highlights: • One-week selective reduction of gluco- and lipo-toxicity in db/db mice was performed. • Selective glucotoxicity reduction increases key pancreatic β-cell factors expression. • Selective glucotoxicity reduction improves β-cell factors over pretreatment levels. • Selective glucotoxicity reduction turns β-cell mass toward increase. • Lipotoxicity reduction has additive effects on glucotoxicity reduction.

A Technology Selection Framework for Integrating Manufacturing within a Supply Chain

DEFF Research Database (Denmark)

Farooq, Sami; O' Brien, Chris

2012-01-01

This paper describes a structured analytical approach for selecting a manufacturing technology. A framework consisting of six integrated steps is proposed by considering the growing importance of supply chains in manufacturing organisations. The framework makes use of Analytical Hierarchy (AHP......) approach combined with Strategic Assessment Model (SAM) to evaluate and select the technologies appropriate for providing overall competitive advantage. The framework is intended to assist industrial managers in promoting manufacturing and supply chain collaboration and coordination by including intra...

60-GHz integrated-circuit high data rate quadriphase shift keying exciter and modulator

Science.gov (United States)

Grote, A.; Chang, K.

1984-01-01

An integrated-circuit quadriphase shift keying (QPSK) exciter and modulator have demonstrated excellent performance directly modulating a carrier frequency of 60 GHz with an output phase error of less than 3 degrees and maximum amplitude error of 0.5 dB. The circuit consists of a 60-GHz Gunn VCO phase-locked to a low-frequency reference source, a 4th subharmonic mixer, and a QPSK modlator packaged into a small volume of 1.8 x 2.5 x 0.35 in. The use of microstrip has the advantages of small size, light-weight, and low-cost fabrication. The unit has the potential for multigigabit data rate applications.

KeyPathwayMinerWeb

DEFF Research Database (Denmark)

List, Markus; Alcaraz, Nicolas; Dissing-Hansen, Martin

2016-01-01

, for instance), KeyPathwayMiner extracts connected sub-networks containing a high number of active or differentially regulated genes (proteins, metabolites) in the molecular profiles. The web interface at (http://keypathwayminer.compbio.sdu.dk) implements all core functionalities of the KeyPathwayMiner tool set......We present KeyPathwayMinerWeb, the first online platform for de novo pathway enrichment analysis directly in the browser. Given a biological interaction network (e.g. protein-protein interactions) and a series of molecular profiles derived from one or multiple OMICS studies (gene expression...... such as data integration, input of background knowledge, batch runs for parameter optimization and visualization of extracted pathways. In addition to an intuitive web interface, we also implemented a RESTful API that now enables other online developers to integrate network enrichment as a web service...

Selecting Candidates for Key Leadership Positions in Program Executive Offices Ground Combat Systems and Combat Service and Combat Service Support

Science.gov (United States)

2016-10-14

start or continue a profitable growth pattern and boost morale and motivation, a poor decision may bring the company to the brink of financial...HON Frank Kendall issued a memorandum titled “Key Leadership Positions and Qualification Criteria” (Kendall, 2013). This memorandum provides a...Chief Developmental Tester • Program Lead, Business Financial Manager SELECTING CANDIDATES FOR KEY LEADERSHIP POSITIONS 4

Behavior Selection of Mobile Robot Based on Integration of Multimodal Information

Science.gov (United States)

Chen, Bin; Kaneko, Masahide

Recently, biologically inspired robots have been developed to acquire the capacity for directing visual attention to salient stimulus generated from the audiovisual environment. On purpose to realize this behavior, a general method is to calculate saliency maps to represent how much the external information attracts the robot's visual attention, where the audiovisual information and robot's motion status should be involved. In this paper, we represent a visual attention model where three modalities, that is, audio information, visual information and robot's motor status are considered, while the previous researches have not considered all of them. Firstly, we introduce a 2-D density map, on which the value denotes how much the robot pays attention to each spatial location. Then we model the attention density using a Bayesian network where the robot's motion statuses are involved. Secondly, the information from both of audio and visual modalities is integrated with the attention density map in integrate-fire neurons. The robot can direct its attention to the locations where the integrate-fire neurons are fired. Finally, the visual attention model is applied to make the robot select the visual information from the environment, and react to the content selected. Experimental results show that it is possible for robots to acquire the visual information related to their behaviors by using the attention model considering motion statuses. The robot can select its behaviors to adapt to the dynamic environment as well as to switch to another task according to the recognition results of visual attention.

A Study of Integrity Evaluation System for Spent Fuel and Selection of the Representative Spent Fuel

International Nuclear Information System (INIS)

Kim, J. G.; Lee, S. K.; Lim, C. J.; Kim, J. K.; Lee, S. J.

2014-01-01

Spent fuel (SF) integrity evaluation is a regulatory requirement that is described in 10 CFR 71(transportation) and 10 CFR 72(storage) of the U. S. NRC licensing requirement. NRC regulation states that retrievability of SF after storage should be ensured and SF integrity under the normal condition must be guaranteed during transportation and handling process that is entailed before/during/after the interim storage. And SF integrity evaluation under the hypothetical accident condition is a core technology element for an assessment of critical, shielding, and containment. In this paper, SF integrity evaluation system which is suitable for domestic situation is suggested, and necessity of representative SF selection and its method is described. The ultimate goal of the SF integrity evaluation is to evaluate a safety margin in case of transportation/ handling/storage of SFs. It means that retrievability of SF after storage should be assured and SF integrity must be guaranteed at normal condition in the process of transportation/handling accompanied before/during/after interim storage. In Korea, SF integrity evaluation system is not established up to date. Especially, representative SF selection technology that is essential to SF integrity evaluation has not been fulfilled. To overcome this situation effectively, the methodology and technology of an overseas agency need to be benchmarked. In this paper, an overseas SF integrity evaluation system is analyzed, and an evaluation system suitable for domestic situation is suggested. Also, necessity of representative SF selection and its method is described

Extended integration the key to future productivity leap

International Nuclear Information System (INIS)

Peebler, R.P.

1996-01-01

This paper reviews the economic benefits and trends in integration of information technology. The paper assesses the historical technologies of simple structure interpretation to complex three- and four-dimensional simulation. It presents historical methods of collecting and analyzing data and a hierarchy of integration that has developed. It shows the economic benefits of integrating computer data bases with multidisciplinary teams to engineer and monitor oil and gas depletion

Performance Analysis of Hierarchical Group Key Management Integrated with Adaptive Intrusion Detection in Mobile ad hoc Networks

Science.gov (United States)

2016-04-05

applications in wireless networks such as military battlefields, emergency response, mobile commerce , online gaming, and collaborative work are based on the...www.elsevier.com/locate/peva Performance analysis of hierarchical group key management integrated with adaptive intrusion detection in mobile ad hoc...Accepted 19 September 2010 Available online 26 September 2010 Keywords: Mobile ad hoc networks Intrusion detection Group communication systems Group

Integrated polymer micro-ring resonators for optical sensing applications

OpenAIRE

Girault , Pauline; Lorrain , Nathalie; Poffo , Luiz; Guendouz , Mohammed; Lemaitre , Jonathan; Carré , Christiane; Gadonna , Michel; Bosc , Dominique; Vignaud , Guillaume

2015-01-01

International audience; Micro-resonators (MR) have become a key element for integrated optical sensors due to their integration capability and their easy fabrication with low cost polymer materials. Nowadays, there is a growing need on MRs as highly sensitive and selective functions especially in the areas of food and health. The context of this work is to implement and study integrated micro-ring resonators devoted to sensing applications. They are fabricated by processing SU8 polymer as cor...

Benchmarking Organisational Capability using The 20 Keys

Directory of Open Access Journals (Sweden)

Dino Petrarolo

2012-01-01

Full Text Available Organisations have over the years implemented many improvement initiatives, many of which were applied individually with no real, lasting improvement. Approaches such as quality control, team activities, setup reduction and many more seldom changed the fundamental constitution or capability of an organisation. Leading companies in the world have come to realise that an integrated approach is required which focuses on improving more than one factor at the same time - by recognising the importance of synergy between different improvement efforts and the need for commitment at all levels of the company to achieve total system-wide improvement.

The 20 Keys approach offers a way to look at the strenqth of organisations and to systemically improve it, one step at a time by focusing on 20 different but interrelated aspects. One feature of the approach is the benchmarking system which forms the main focus of this paper. The benchmarking system is introduced as an important part of the 20 Keys philosophy in measuring organisational strength. Benchmarking results from selected South African companies are provided, as well as one company's results achieved through the adoption of the 20 Keys philosophy.

Mergeomics: a web server for identifying pathological pathways, networks, and key regulators via multidimensional data integration.

Science.gov (United States)

Arneson, Douglas; Bhattacharya, Anindya; Shu, Le; Mäkinen, Ville-Petteri; Yang, Xia

2016-09-09

Human diseases are commonly the result of multidimensional changes at molecular, cellular, and systemic levels. Recent advances in genomic technologies have enabled an outpour of omics datasets that capture these changes. However, separate analyses of these various data only provide fragmented understanding and do not capture the holistic view of disease mechanisms. To meet the urgent needs for tools that effectively integrate multiple types of omics data to derive biological insights, we have developed Mergeomics, a computational pipeline that integrates multidimensional disease association data with functional genomics and molecular networks to retrieve biological pathways, gene networks, and central regulators critical for disease development. To make the Mergeomics pipeline available to a wider research community, we have implemented an online, user-friendly web server ( http://mergeomics. idre.ucla.edu/ ). The web server features a modular implementation of the Mergeomics pipeline with detailed tutorials. Additionally, it provides curated genomic resources including tissue-specific expression quantitative trait loci, ENCODE functional annotations, biological pathways, and molecular networks, and offers interactive visualization of analytical results. Multiple computational tools including Marker Dependency Filtering (MDF), Marker Set Enrichment Analysis (MSEA), Meta-MSEA, and Weighted Key Driver Analysis (wKDA) can be used separately or in flexible combinations. User-defined summary-level genomic association datasets (e.g., genetic, transcriptomic, epigenomic) related to a particular disease or phenotype can be uploaded and computed real-time to yield biologically interpretable results, which can be viewed online and downloaded for later use. Our Mergeomics web server offers researchers flexible and user-friendly tools to facilitate integration of multidimensional data into holistic views of disease mechanisms in the form of tissue-specific key regulators

SELECTED REQUIREMENTS OF INTEGRATED MANAGEMENT SYSTEMS BASED ON PAS 99 SPECIFICATION

Directory of Open Access Journals (Sweden)

Paweł Nowicki

2013-03-01

Full Text Available The aim this research was to analyze the ways of integration of management systems in food sector. The study involved the documentation, audits, corrective and preventive actions and management's review phases described in the specification PAS 99, which is one of common elements of integrated management systems. Four organizations were selected for the study. The organizations had introduced and certified at least two standardized management systems. It was assumed that the investigated organizations should have implemented the HACCP system. Studies were conducted as a case study. The employees responsible for the functioning of management systems were interviewed in all four organizations. The study was conducted in the form of in-depth interviews based on pre-prepared script. The scenario was developed based on the PAS 99 guideline. The process of integration of management systems implemented in the studied companies reveals the full compliance of an integrated management system with PASS 99 in the policy area.

Overview of the New England wind integration. Study and selected results

Energy Technology Data Exchange (ETDEWEB)

Norden, John R.; Henson, William L.W. [ISO New England, Holyoke, MA (United States)

2010-07-01

ISO New England commissioned a comprehensive wind integration study to be completed in the early fall of 2010: the New England Wind Integration Study (NEWIS). The NEWIS assesses the efects of scenarios that encompass a range of wind-power penetrations in New England using statistical and simulation analysis including the development of a mesoscale wind-to-power model for the New England and Maritime wind resources areas. It also determines the impacts of integrating increasing amounts of wind generation resources for New England, as well as, the measures that may be available to the ISO for responding to any challenges while enabling the integration of wind-power. This paper provides an overview of the study then focuses on selected near final results, particularly with regard to the varying capacity factor, capacity value and siting that were determined as part of the study. The full results of the NEWIS will be released in the fall of 2010. (orig.)

Integrative approaches to the prediction of protein functions based on the feature selection

Directory of Open Access Journals (Sweden)

Lee Hyunju

2009-12-01

Full Text Available Abstract Background Protein function prediction has been one of the most important issues in functional genomics. With the current availability of various genomic data sets, many researchers have attempted to develop integration models that combine all available genomic data for protein function prediction. These efforts have resulted in the improvement of prediction quality and the extension of prediction coverage. However, it has also been observed that integrating more data sources does not always increase the prediction quality. Therefore, selecting data sources that highly contribute to the protein function prediction has become an important issue. Results We present systematic feature selection methods that assess the contribution of genome-wide data sets to predict protein functions and then investigate the relationship between genomic data sources and protein functions. In this study, we use ten different genomic data sources in Mus musculus, including: protein-domains, protein-protein interactions, gene expressions, phenotype ontology, phylogenetic profiles and disease data sources to predict protein functions that are labelled with Gene Ontology (GO terms. We then apply two approaches to feature selection: exhaustive search feature selection using a kernel based logistic regression (KLR, and a kernel based L1-norm regularized logistic regression (KL1LR. In the first approach, we exhaustively measure the contribution of each data set for each function based on its prediction quality. In the second approach, we use the estimated coefficients of features as measures of contribution of data sources. Our results show that the proposed methods improve the prediction quality compared to the full integration of all data sources and other filter-based feature selection methods. We also show that contributing data sources can differ depending on the protein function. Furthermore, we observe that highly contributing data sets can be similar among

Key issues of the common French-German safety approach for future PWRs

International Nuclear Information System (INIS)

Frisch, W.; Rohde, J.; Gros, G.; Queniart, D.

1996-01-01

The general common safety approach issued in May 1993 contains safety objectives, general principles and already some technical principles. Based on general safety approach, detailed recommendations have been developed in 1994 on key issues such as: system design and use of PSA; integrity of the primary circuit; external hazards; severe accidents and containment design; radiological consequences of reference accidents and low pressure core melt accidents. A selection of the detailed recommendations is presented in the full paper. (author)

Analysis of selected methods for the recovery of encrypted WEP key

Science.gov (United States)

Wójtowicz, Sebastian; Belka, Radosław

2014-11-01

This paper deals with some of the WEP (Wired Equivalent Privacy) key decryption methods based on aircrack-ng software, which was embedded in Backtrack operating system (Linux distribution). The 64-bit (40-bit) and 128-bit (104- bit) key encrypted with RC4 cipher weakness was shown. Research methods were made in different network environments. In this work we compared different types of keys to check how strong the RC4 stream cipher can be. The 40-bit and 104-bit WEP key has been tested on IEEE 802.11 based wireless LAN using laptop with live-CD Linux operating system. A short analysis of key creation methods was performed to compare the amount of time necessary to decrypt random and nonrandom WEP keys.

Criteria for the selection of graphites for HTR integral block fuel elements

International Nuclear Information System (INIS)

Knowles, A.N.

1980-01-01

This paper is concerned with the special requirements for integral block fuel elements of the type first used in the Fort St. Vrain reactor. The main idea of these elements is that the carrier block and separate graphite clad fuel pins are combined into a single monolith. This combination leads to lower fabrication costs and some improvement in the thermal performance (lower temperature difference between fuel and the surface of heat transfer into the coolant). The advent of block fuel for HTRs of the Fort St. Vrain type has placed a fresh emphasis on the selection of graphite for block manufacture in respect of physical properties. This is because the temperature distributions typical of such fuelled blocks lead to shutdown stresses close to the maximum the graphite can sustain without damage. Figures presented in this paper suggest that the physical properties of the graphite can play a relatively large part in reducing such stress levels and that guidance on the key requirements for suitable specifications is therefore particularly needed by the manufacturers of fuel block graphites. While graphites for fuel blocks have this special need for combinations of physical properties which lead to low thermal and shrinkage stresses, the other characteristics must also receive attention. A low graphite cost combined with good homogeneity in the brick, so that waste minimized, are still necessary, while isotropy is also very important

Identifying Key Issues and Potential Solutions for Integrated Arrival, Departure, Surface Operations by Surveying Stakeholder Preferences

Science.gov (United States)

Aponso, Bimal; Coppenbarger, Richard A.; Jung, Yoon; Quon, Leighton; Lohr, Gary; O’Connor, Neil; Engelland, Shawn

2015-01-01

NASA's Aeronautics Research Mission Directorate (ARMD) collaborates with the FAA and industry to provide concepts and technologies that enhance the transition to the next-generation air-traffic management system (NextGen). To facilitate this collaboration, ARMD has a series of Airspace Technology Demonstration (ATD) sub-projects that develop, demonstrate, and transitions NASA technologies and concepts for implementation in the National Airspace System (NAS). The second of these sub-projects, ATD-2, is focused on the potential benefits to NAS stakeholders of integrated arrival, departure, surface (IADS) operations. To determine the project objectives and assess the benefits of a potential solution, NASA surveyed NAS stakeholders to understand the existing issues in arrival, departure, and surface operations, and the perceived benefits of better integrating these operations. NASA surveyed a broad cross-section of stakeholders representing the airlines, airports, air-navigation service providers, and industry providers of NAS tools. The survey indicated that improving the predictability of flight times (schedules) could improve efficiency in arrival, departure, and surface operations. Stakeholders also mentioned the need for better strategic and tactical information on traffic constraints as well as better information sharing and a coupled collaborative planning process that allows stakeholders to coordinate IADS operations. To assess the impact of a potential solution, NASA sketched an initial departure scheduling concept and assessed its viability by surveying a select group of stakeholders for a second time. The objective of the departure scheduler was to enable flights to move continuously from gate to cruise with minimal interruption in a busy metroplex airspace environment using strategic and tactical scheduling enhanced by collaborative planning between airlines and service providers. The stakeholders agreed that this departure concept could improve schedule

Effect of Integrated Yoga Module on Selected Psychological Variables among Women with Anxiety Problem.

Science.gov (United States)

Parthasarathy, S; Jaiganesh, K; Duraisamy

2014-01-01

The implementation of yogic practices has proven benefits in both organic and psychological diseases. Forty-five women with anxiety selected by a random sampling method were divided into three groups. Experimental group I was subjected to asanas, relaxation and pranayama while Experimental group II was subjected to an integrated yoga module. The control group did not receive any intervention. Anxiety was measured by Taylor's Manifest Anxiety Scale before and after treatment. Frustration was measured through Reaction to Frustration Scale. All data were spread in an Excel sheet to be analysed with SPSS 16 software using analysis of covariance (ANCOVA). Selected yoga and asanas decreased anxiety and frustration scores but treatment with an integrated yoga module resulted in significant reduction of anxiety and frustration. To conclude, the practice of asanas and yoga decreased anxiety in women, and yoga as an integrated module significantly improved anxiety scores in young women with proven anxiety without any ill effects.

The Selective Cue Integration Framework: A Theory of Postidentification Witness Confidence Assessment

Science.gov (United States)

Charman, Steve D.; Carlucci, Marianna; Vallano, Jon; Gregory, Amy Hyman

2010-01-01

The current manuscript proposes a theory of how witnesses assess their confidence following a lineup identification, called the selective cue integration framework (SCIF). Drawing from past research on the postidentification feedback effect, the SCIF details a three-stage process of confidence assessment that is based largely on a…

Legislation on violence against women: overview of key components.

Science.gov (United States)

Ortiz-Barreda, Gaby; Vives-Cases, Carmen

2013-01-01

This study aimed to determine if legislation on violence against women (VAW) worldwide contains key components recommended by the Pan American Health Organization (PAHO) and the United Nations (UN) to help strengthen VAW prevention and provide better integrated victim protection, support, and care. A systematic search for VAW legislation using international legal databases and other electronic sources plus data from previous research identified 124 countries/territories with some type of VAW legislation. Full legal texts were found for legislation from 104 countries/territories. Those available in English, Portuguese, and Spanish were downloaded and compiled and the selection criteria applied (use of any of the common terms related to VAW, including intimate partner violence (IPV), and reference to at least two of six sectors (education, health, judicial system, mass media, police, and social services) with regard to VAW interventions (protection, support, and care). A final sample from 80 countries/territories was selected and analyzed for the presence of key components recommended by PAHO and the UN (reference to the term "violence against women" in the title; definitions of different types of VAW; identification of women as beneficiaries; and promotion of (reference to) the participation of multiple sectors in VAW interventions). Few countries/territories specifically identified women as the beneficiaries of their VAW legislation, including those that labeled their legislation "domestic violence" law ( n = 51), of which only two explicitly mentioned women as complainants/survivors. Only 28 countries/territories defined the main forms of VAW (economic, physical, psychological, and sexual) in their VAW legislation. Most highlighted the role of the judicial system, followed by that of social services and the police. Only 28 mentioned the health sector. Despite considerable efforts worldwide to strengthen VAW legislation, most VAW laws do not incorporate the key

Experimental integration of quantum key distribution and gigabit-capable passive optical network

Science.gov (United States)

Sun, Wei; Wang, Liu-Jun; Sun, Xiang-Xiang; Mao, Yingqiu; Yin, Hua-Lei; Wang, Bi-Xiao; Chen, Teng-Yun; Pan, Jian-Wei

2018-01-01

Quantum key distribution (QKD) ensures information-theoretic security for the distribution of random bits between two remote parties. To extend QKD applications to fiber-to-the-home optical communications, such as gigabit-capable passive optical networks (GPONs), an effective method is the use of wavelength-division multiplexing. However, the Raman scattering noise from intensive classical traffic and the huge loss introduced by the beam splitter in a GPON severely limits the performance of QKD. Here, we demonstrate the integration of QKD and a commercial GPON system with fiber lengths up to 14 km, in which the maximum splitting ratio of the beam splitter reaches 1:64. By placing the QKD transmitter on the optical line terminal side, we reduce the Raman noise collected at the QKD receiver. Using a bypass structure, the loss of the beam splitter is circumvented effectively. Our results pave the way to extending the applications of QKD to last-mile communications.

An Evaluation Model To Select an Integrated Learning System in a Large, Suburban School District.

Science.gov (United States)

Curlette, William L.; And Others

The systematic evaluation process used in Georgia's DeKalb County School System to purchase comprehensive instructional software--an integrated learning system (ILS)--is described, and the decision-making model for selection is presented. Selection and implementation of an ILS were part of an instructional technology plan for the DeKalb schools…

Maximising the recovery of low grade heat: An integrated heat integration framework incorporating heat pump intervention for simple and complex factories

International Nuclear Information System (INIS)

Miah, J.H.; Griffiths, A.; McNeill, R.; Poonaji, I.; Martin, R.; Leiser, A.; Morse, S.; Yang, A.; Sadhukhan, J.

2015-01-01

Highlights: • A new practical heat integration framework incorporating heat pump technology for simple and complex food factories. • A decision making procedure was proposed to select process or utility heat integration in complex and diverse factories. • New stream classifications proposed to identify and compare streams linked between process and utility, especially waste heat. • A range of ‘Heat Pump Thresholds’ to identify and compare heat pump configurations with steam generation combustion boiler. - Abstract: The recovery of heat has long been a key measure to improving energy efficiency and maximising the heat recovery of factories by Pinch analysis. However, a substantial amount of research has been dedicated to conventional heat integration where low grade heat is often ignored. Despite this, the sustainability challenges facing the process manufacturing community are turning interest on low grade energy recovery systems to further advance energy efficiency by technological interventions such as heat pumps. This paper presents a novel heat integration framework incorporating technological interventions for both simple and complex factories to evaluate all possible heat integration opportunities including low grade and waste heat. The key features of the framework include the role of heat pumps to upgrade heat which can significantly enhance energy efficiency; the selection process of heat pump designs which was aided by the development of ‘Heat Pump Thresholds’ to decide if heat pump designs are cost-competitive with steam generation combustion boiler; a decision making procedure to select process or utility heat integration in complex and diverse factories; and additional stream classifications to identify and separate streams that can be practically integrated. The application of the framework at a modified confectionery factory has yielded four options capable of delivering a total energy reduction of about 32% with an economic payback

Selective pressures to maintain attachment site specificity of integrative and conjugative elements.

Directory of Open Access Journals (Sweden)

Kayla L Menard

Full Text Available Integrative and conjugative elements (ICEs are widespread mobile genetic elements that are usually found integrated in bacterial chromosomes. They are important agents of evolution and contribute to the acquisition of new traits, including antibiotic resistances. ICEs can excise from the chromosome and transfer to recipients by conjugation. Many ICEs are site-specific in that they integrate preferentially into a primary attachment site in the bacterial genome. Site-specific ICEs can also integrate into secondary locations, particularly if the primary site is absent. However, little is known about the consequences of integration of ICEs into alternative attachment sites or what drives the apparent maintenance and prevalence of the many ICEs that use a single attachment site. Using ICEBs1, a site-specific ICE from Bacillus subtilis that integrates into a tRNA gene, we found that integration into secondary sites was detrimental to both ICEBs1 and the host cell. Excision of ICEBs1 from secondary sites was impaired either partially or completely, limiting the spread of ICEBs1. Furthermore, induction of ICEBs1 gene expression caused a substantial drop in proliferation and cell viability within three hours. This drop was dependent on rolling circle replication of ICEBs1 that was unable to excise from the chromosome. Together, these detrimental effects provide selective pressure against the survival and dissemination of ICEs that have integrated into alternative sites and may explain the maintenance of site-specific integration for many ICEs.

The search for Pleiades in trait constellations: functional integration and phenotypic selection in the complex flowers of Morrenia brachystephana (Apocynaceae).

Science.gov (United States)

Baranzelli, M C; Sérsic, A N; Cocucci, A A

2014-04-01

Pollinator-mediated natural selection on single traits, such as corolla tube or spur length, has been well documented. However, flower phenotypes are usually complex, and selection is expected to act on several traits that functionally interact rather than on a single isolated trait. Despite the fact that selection on complex phenotypes is expectedly widespread, multivariate selection modelling on such phenotypes still remains under-explored in plants. Species of the subfamily Asclepiadoideae (Apocynaceae) provide an opportunity to study such complex flower contrivances integrated by fine-scaled organs from disparate developmental origin. We studied the correlation structure among linear floral traits (i) by testing a priori morphological, functional or developmental hypotheses among traits and (ii) by exploring the organization of flower covariation, considering alternative expectations of modular organization or whole flower integration through conditional dependence analysis (CDA) and integration matrices. The phenotypic selection approach was applied to determine whether floral traits involved in the functioning of the pollination mechanism were affected by natural selection. Floral integration was low, suggesting that flowers are organized in more than just one correlation pleiad; our hypothetical functional correlation matrix was significantly correlated with the empirical matrix, and the CDA revealed three putative modules. Analyses of phenotypic selection showed significant linear and correlational gradients, lending support to expectations of functional interactions between floral traits. Significant correlational selection gradients found involved traits of different floral whorls, providing evidence for the existence of functional integration across developmental domains. © 2014 The Authors. Journal of Evolutionary Biology © 2014 European Society For Evolutionary Biology.

A fast and versatile quantum key distribution system with hardware key distillation and wavelength multiplexing

International Nuclear Information System (INIS)

Walenta, N; Gisin, N; Guinnard, O; Houlmann, R; Korzh, B; Lim, C W; Lunghi, T; Portmann, C; Thew, R T; Burg, A; Constantin, J; Caselunghe, D; Kulesza, N; Legré, M; Monat, L; Soucarros, M; Trinkler, P; Junod, P; Trolliet, G; Vannel, F

2014-01-01

We present a compactly integrated, 625 MHz clocked coherent one-way quantum key distribution system which continuously distributes secret keys over an optical fibre link. To support high secret key rates, we implemented a fast hardware key distillation engine which allows for key distillation rates up to 4 Mbps in real time. The system employs wavelength multiplexing in order to run over only a single optical fibre. Using fast gated InGaAs single photon detectors, we reliably distribute secret keys with a rate above 21 kbps over 25 km of optical fibre. We optimized the system considering a security analysis that respects finite-key-size effects, authentication costs and system errors for a security parameter of ε QKD  = 4 × 10 −9 . (paper)

Two-Dimensional Key Table-Based Group Key Distribution in Advanced Metering Infrastructure

Directory of Open Access Journals (Sweden)

Woong Go

2014-01-01

Full Text Available A smart grid provides two-way communication by using the information and communication technology. In order to establish two-way communication, the advanced metering infrastructure (AMI is used in the smart grid as the core infrastructure. This infrastructure consists of smart meters, data collection units, maintenance data management systems, and so on. However, potential security problems of the AMI increase owing to the application of the public network. This is because the transmitted information is electricity consumption data for charging. Thus, in order to establish a secure connection to transmit electricity consumption data, encryption is necessary, for which key distribution is required. Further, a group key is more efficient than a pairwise key in the hierarchical structure of the AMI. Therefore, we propose a group key distribution scheme using a two-dimensional key table through the analysis result of the sensor network group key distribution scheme. The proposed scheme has three phases: group key predistribution, selection of group key generation element, and generation of group key.

Integrated basic treatment of activated carbon for enhanced CO{sub 2} selectivity

Energy Technology Data Exchange (ETDEWEB)

Adelodun, Adedeji Adebukola; Jo, Young-Min, E-mail: ymjo@khu.ac.kr

2013-12-01

We attempted the use of three chemical agents viz nitric acid (HN), calcium nitrate (CaN) and calcium ethanoate (CaEt) to achieve enhanced CO{sub 2} selective adsorption by activated carbon (AC). In dry phase treatment, microporous coconut shell-based carbon (CS) exhibits higher CO{sub 2} capacity than coal-based. However, upon wet-phase pre-treatment, modified CS samples showed lesser CO{sub 2} adsorption efficiency. Surface characterization with X-ray photoelectron spectroscopy confirms the presence of calcium and amine species on the samples with integrated treatment (A-CaN). These samples recorded the highest low-level CO{sub 2} capture despite calcinated CaEt-doped samples (C-CaEt) showing the highest value for pure and high level CO{sub 2} adsorption capacities. The slope and linearity values of isobaric desorption were used to estimate the proportion of CO{sub 2} chemisorbed and heterogeneity of the adsorbents’ surfaces respectively. Consequently, integrated basic impregnation provides the most efficient adsorbents for selective adsorption of both indoor and outdoor CO{sub 2} levels.

The fuzzy TOPSIS and generalized Choquet fuzzy integral algorithm for nuclear power plant site selection - a case study from Turkey

International Nuclear Information System (INIS)

Kurt, Ünal

2014-01-01

The location selection for nuclear power plant (NPP) is a strategic decision, which has significant impact on the economic operation of the plant and sustainable development of the region. This paper proposes fuzzy TOPSIS and generalized Choquet fuzzy integral algorithm for evaluation and selection of optimal locations for NPP in Turkey. Many sub-criteria such as geological, social, touristic, transportation abilities, cooling water capacity and nearest to consumptions markets are taken into account. Among the evaluated locations, according to generalized Choquet fuzzy integral method, Inceburun–Sinop was selected as a study site due to its highest performance and meeting most of the investigated criteria. The Inceburun-Sinop is selected by generalized Choquet fuzzy integral and fuzzy TOPSIS Iğneada–Kırklareli took place in the first turn. The Mersin–Akkuyu is not selected in both methods. (author)

Selective epitaxial growth of monolithically integrated GaN-based light emitting diodes with AlGaN/GaN driving transistors

International Nuclear Information System (INIS)

Liu, Zhaojun; Ma, Jun; Huang, Tongde; Liu, Chao; May Lau, Kei

2014-01-01

In this Letter, we report selective epitaxial growth of monolithically integrated GaN-based light emitting diodes (LEDs) with AlGaN/GaN high-electron-mobility transistor (HEMT) drivers. A comparison of two integration schemes, selective epitaxial removal (SER), and selective epitaxial growth (SEG) was made. We found the SER resulted in serious degradation of the underlying LEDs in a HEMT-on-LED structure due to damage of the p-GaN surface. The problem was circumvented using the SEG that avoided plasma etching and minimized device degradation. The integrated HEMT-LEDs by SEG exhibited comparable characteristics as unintegrated devices and emitted modulated blue light by gate biasing

Road map for selected key measurements from LHCb

CERN Document Server

Adeva, B.; Affolder, A.; Ajaltouni, Z.; Albrecht, J.; Alessio, F.; Alexander, M.; Alvarez Cartelle, P.; Alves, A.A., Jr; Amato, S.; Amhis, Y.; Amoraal, J.; Anderson, J.; Aquines Gutierrez, O.; Arrabito, L.; Artuso, M.; Aslanides, E.; Auriemma, G.; Bachmann, S.; Bagaturia, Y.; Bailey, D.S.; Balagura, V.; Baldini, W.; Pazos, MdC.Barandela; Barlow, R.J.; Barsuk, S.; Bates, A.; Bauer, C.; Bauer, Th.; Bay, A.; Bediaga, I.; Belous, K.; Belyaev, I.; Benayoun, M.; Bencivenni, G.; Bernet, R.; Bettler, M.O.; Bizzeti, A.; Blake, T.; Blanc, F.; Blanks, C.; Blouw, J.; Blusk, S.; Bobrov, A.; Bocci, V.; Bondar, A.; Bondar, N.; Bonivento, W.; Borghi, S.; Borgia, A.; Bos, E.; Bowcock, T.J.V.; Bozzi, C.; Bressieux, J.; Brisbane, S.; Britsch, M.; Brook, N.H.; Brown, H.; Buchler-Germann, A.; Buytaert, J.; Cachemiche, J.P.; Cadeddu, S.; Caicedo Carvajal, J.M.; Callot, O.; Calvi, M.; Calvo Gomez, M.; Camboni, A.; Cameron, W.; Campana, P.; Carbone, A.; Carboni, G.; Cardini, A.; Carson, L.; Carvalho Akiba, K.; Casse, G.; Cattaneo, M.; Charles, M.; Charpentier, Ph.; Chlopik, A.; Ciambrone, P.; Cid Vidal, X.; Clark, P.J.; Clarke, P.E.L.; Clemencic, M.; Cliff, H.V.; Closier, J.; Coca, C.; Coco, V.; Cogan, J.; Collins, P.; Constantin, F.; Conti, G.; Contu, A.; Corti, G.; Cowan, G.A.; D'Almagne, B.; D'Ambrosio, C.; d'Enterria, D.G.; Da Silva, W.; David, P.; De Bonis, I.; De Capua, S.; De Cian, M.; De Lorenzi, F.; De Miranda, J.M.; De Paula, L.; De Simone, P.; De Vries, H.; Decamp, D.; Degaudenzi, H.; Deissenroth, M.; Del Buono, L.; Deplano, C.; Deschamps, O.; Dettori, F.; Dickens, J.; Dijkstra, H.; Dima, M.; Donleavy, S.; Reis, A.C.dos; Dovbnya, A.; Pree, T.Du; Duval, P.Y.; Dwyer, L.; Dzhelyadin, R.; Eames, C.; Easo, S.; Egede, U.; Egorychev, V.; Eisele, F.; Eisenhardt, S.; Eklund, L.; Esperante Pereira, D.; Esteve, L.; Eydelman, S.; Fanchini, E.; Farber, C.; Fardell, G.; Farinelli, C.; Farry, S.; Fave, V.; Fernandez Albor, V.; Ferro-Luzzi, M.; Filippov, S.; Fitzpatrick, C.; Fontanelli, F.; Forty, R.; Frank, M.; Frei, C.; Frosini, M.; Fungueirino Pazos, J.L.; Furcas, S.; Gallas Torreira, A.; Galli, D.; Gandelman, M.; Gao, Y.; Garnier, J-C.; Garrido, L.; Gaspar, C.; Gauvin, N.; Gersabeck, M.; Gershon, T.; Ghez, Ph.; Gibson, V.; Gilitsky, Yu.; Gligorov, V.V.; Gobel, C.; Golubkov, D.; Golutvin, A.; Gomes, A.; Grabalosa Gandara, M.; Graciani Diaz, R.; Granado Cardoso, L.A.; Grauges, E.; Graziani, G.; Grecu, A.; Guerrer, G.; Gushchin, E.; Guz, Yu.; Guzik, Z.; Gys, T.; Hachon, F.; Haefeli, G.; Haines, S.C.; Hampson, T.; Hansmann-Menzemer, S.; Harji, R.; Harnew, N.; Harrison, P.F.; He, J.; Hennessy, K.; Henrard, P.; Hernando Morata, J.A.; Hicheur, A.; Hicks, E.; Hofmann, W.; Holubyev, K.; Hopchev, P.; Hulsbergen, W.; Hunt, P.; Huse, T.; Huston, R.S.; Hutchcroft, D.; Iakovenko, V.; Escudero, C.Iglesias; Imong, J.; Jacobsson, R.; Jahjah Hussein, M.; Jans, E.; Jansen, F.; Jaton, P.; Jean-Marie, B.; John, M.; Jones, C.R.; Jost, B.; Kapusta, F.; Karbach, T.M.; Keaveney, J.; Kerzel, U.; Ketel, T.; Keune, A.; Khalil, S.; Khanji, B.; Kim, Y.M.; Knecht, M.; Knopf, J.; Koblitz, S.; Konoplyannikov, A.; Koppenburg, P.; Korolko, I.; Kozlinskiy, A.; Krasowski, M.; Kravchuk, L.; Krokovny, P.; Kruzelecki, K.; Kucharczyk, M.; Kudryashov, I.; Kvaratskheliya, T.; Lacarrere, D.; Lai, A.; Lambert, R.W.; Lanfranchi, G.; Langenbruch, C.; Latham, T.; Le Gac, R.; Lefevre, R.; Leflat, A.; Lefrancois, J.; Leroy, O.; Lessnoff, K.; Li, L.; Li, Y.Y.; Libby, J.; Lieng, M.; Lindner, R.; Lindsey, S.; Linn, C.; Liu, B.; Liu, G.; Lopes, J.H.; Lopez Asamar, E.; Luisier, J.; Machefert, F.; Machikhiliyan, I.; Maciuc, F.; Maev, O.; Magnin, J.; Maier, A.; Mamunur, R.M.D.; Manca, G.; Mancinelli, G.; Mangiafave, N.; Marconi, U.; Marin, F.; Marks, J.; Martellotti, G.; Martens, A.; Martin, L.; Martinez Santos, D.; Mathe, Z.; Matteuzzi, C.; Matveev, V.; Mazurov, A.; McGregor, G.; Mcharek, B.; Mclean, C.; McNulty, R.; Merk, M.; Merkel, J.; Merkin, M.; Messi, R.; Metlica, F.C.D.; Michalowski, J.; Miglioranzi, S.; Minard, M.N.; Monteil, S.; Moran, D.; Morris, J.V.; Mountain, R.; Mous, I.; Muheim, F.; Muresan, R.; Murtas, F.; Muryn, B.; Musy, M.; Mylroie-Smith, J.; Naik, P.; Nakada, T.; Nandakumar, R.; Nardulli, J.; Natkaniec, Z.; Nedos, M.; Needham, M.; Neufeld, N.; Nicolas, L.; Nies, S.; Niess, V.; Nikitin, N.; Noor, A.; Oblakowska-Mucha, A.; Obraztsov, V.; Oggero, S.; Okhrimenko, O.; Oldeman, R.; Orlandea, M.; Ostankov, A.; Palacios, J.; Palutan, M.; Panman, J.; Papadelis, A.; Papanestis, A.; Pappagallo, M.; Parkes, C.; Passaleva, G.; Patel, G.D.; Patel, M.; Paterson, S.K.; Patrick, G.N.; Pauna, E.; Pauna, C.; Pavel, C.; Pazos Alvarez, A.; Pellegrino, A.; Penso, G.; Pepe Altarelli, M.; Perazzini, S.; Perego, D.L.; Perez-Calero Yzquierdo, A.; Perez Trigo, E.; Perret, P.; Pessina, G.; Petrella, A.; Petrolini, A.; Pietrzyk, B.; Pinci, D.; Playfer, S.; Plo Casasus, M.; Polok, G.; Poluektov, A.; Polycarpo, E.; Popov, D.; Popovici, B.; Poss, S.; Potterat, C.; Powell, A.; Pozzi, S.; Pugatch, V.; Puig Navarro, A.; Qian, W.; Rademacker, J.H.; Rakotomiaramanana, B.; Raniuk, I.; Raven, G.; Redford, S.; Reece, W.; Ricciardi, S.; Rinnert, K.; Robbe, P.; Rodrigues, E.; Rodrigues, F.; Rodriguez Cobo, C.; Rodriguez Perez, P.; Rogers, G.J.; Romanovsky, V.; Rospabe, G.; Ruf, T.; Ruiz, H.; Sabatino, G.; Saborido Silva, J.J.; Sagidova, N.; Saitta, B.; Salzmann, C.; Sambade Varela, A.; Sannino, M.; Santacesaria, R.; Santinelli, R.; Santovetti, E.; Sapunov, M.; Sarti, A.; Satriano, C.; Satta, A.; Savrie, M.; Savrina, D.; Schaack, P.; Schiller, M.; Schleich, S.; Schmelling, M.; Schmidt, B.; Schneider, O.; Schopper, A.; Schune, M.H.; Schwemmer, R.; Sciubba, A.; Seco, M.; Semennikov, A.; Senderowska, K.; Serra, N.; Serrano, J.; Shao, B.; Shapkin, M.; Shapoval, I.; Shatalov, P.; Shcheglov, Y.; Shears, T.; Shekhtman, L.; Shevchenko, V.; Simioni, E.; Skottowe, H.P.; Skwarnicki, T.; Smith, A.C.; Sobczak, K.; Soler, F.J.P.; Solomin, A.; Somogy, P.; Soomro, F.; De Paula, B.Souza; Spaan, B.; Sparkes, A.; Spiridenkov, E.; Spradlin, P.; Stagni, F.; Steinkamp, O.; Stoica, S.; Stone, S.; Straumann, U.; Styles, N.; Syryczynski, K.; Szczekowski, M.; Szczypka, P.; Szumlak, T.; T'Jampens, S.; Terrier, H.; Teubert, F.; Thomas, C.; Thomas, E.; Tobin, M.; Topp-Joergensen, S.; Tran, M.T.; Traynor, S.; Tsaregorodtsev, A.; Tuning, N.; Ukleja, A.; Ullaland, O.; Uwer, U.; Vagnoni, V.; Valenti, G.; van Beuzekom, M.; van den Brand, J.; van Eijk, D.; van Herwijnen, E.; van Lysebetten, A.; van Tilburg, J.; Vazquez Gomez, R.; Vazquez Regueiro, P.; Vecchi, S.; Velthuis, J.J.; Veltri, M.; Vervink, K.; Viaud, B.; Videau, I.; Vilasis-Cardona, X.; Vollhardt, A.; Vorobyev, A.; Vorobyev, An.; Voss, H.; Wacker, K.; Wandernoth, S.; Wang, J.; Ward, D.R.; Websdale, D.; Whitehead, M.; Wiedner, D.; Wiggers, L.; Wilkinson, G.; Williams, M.; Wilson, F.F.; Witek, M.; Witzeling, W.; Wotton, S.A.; Wyllie, K.; Xie, Y.; Xing, F.; Yang, Z.; Ybeles Smit, G.; Young, R.; Yushchenko, O.; Zhang, L.; Zhang, Y.; Zhelezov, A.; Zwahlen, N.

2010-01-01

Six of the key physics measurements that will be made by the LHCb experiment, concerning CP asymmetries and rare B decays, are discussed in detail. The "road map" towards the precision measurements is presented, including the use of control channels and other techniques to understand the performance of the detector with the first data from the LHC.

Selection, integration, and conflict monitoring; assessing the nature and generality of prefrontal cognitive control mechanisms.

Science.gov (United States)

Badre, David; Wagner, Anthony D

2004-02-05

Prefrontal cortex (PFC) supports flexible behavior by mediating cognitive control, though the elemental forms of control supported by PFC remain a central debate. Dorsolateral PFC (DLPFC) is thought to guide response selection under conditions of response conflict or, alternatively, may refresh recently active representations within working memory. Lateral frontopolar cortex (FPC) may also adjudicate response conflict, though others propose that FPC supports higher order control processes such as subgoaling and integration. Anterior cingulate cortex (ACC) is hypothesized to upregulate response selection by detecting response conflict; it remains unclear whether ACC functions generalize beyond monitoring response conflict. The present fMRI experiment directly tested these competing theories regarding the functional roles of DLPFC, FPC, and ACC. Results reveal dissociable control processes in PFC, with mid-DLPFC selectively mediating resolution of response conflict and FPC further mediating subgoaling/integration. ACC demonstrated a broad sensitivity to control demands, suggesting a generalized role in modulating cognitive control.

A New Integrated Threshold Selection Methodology for Spatial Forecast Verification of Extreme Events

Science.gov (United States)

Kholodovsky, V.

2017-12-01

Extreme weather and climate events such as heavy precipitation, heat waves and strong winds can cause extensive damage to the society in terms of human lives and financial losses. As climate changes, it is important to understand how extreme weather events may change as a result. Climate and statistical models are often independently used to model those phenomena. To better assess performance of the climate models, a variety of spatial forecast verification methods have been developed. However, spatial verification metrics that are widely used in comparing mean states, in most cases, do not have an adequate theoretical justification to benchmark extreme weather events. We proposed a new integrated threshold selection methodology for spatial forecast verification of extreme events that couples existing pattern recognition indices with high threshold choices. This integrated approach has three main steps: 1) dimension reduction; 2) geometric domain mapping; and 3) thresholds clustering. We apply this approach to an observed precipitation dataset over CONUS. The results are evaluated by displaying threshold distribution seasonally, monthly and annually. The method offers user the flexibility of selecting a high threshold that is linked to desired geometrical properties. The proposed high threshold methodology could either complement existing spatial verification methods, where threshold selection is arbitrary, or be directly applicable in extreme value theory.

Fundamental study on the size and inter-key spacing of numeric keys for touch screen.

Science.gov (United States)

Harada, H; Katsuura, T; Kikuchi, Y

1996-12-01

The purpose of this study was to reveal the optimum size and inter-key spacing of numeric square keys for touch screens. Six male students (22-25 years old) and three female students (21-24 years old) volunteered as subjects for this experiment. Each subject took part in data entry tasks using numeric square keys of touch devices. The sizes of keys were 6, 12, 21, 30 and 39 mm and each the inter-key spacing was 0, 3, 6, 12 and 21 mm. Response times with key sizes of 6 and 12 mm were significantly slower than with key sizes of 21 and 30 mm (p touch screens should be more than 21 mm and optimum inter-key spacing should be from 3 to 6 mm. Optimum key size, however, must be selected with regard to the limitation of screen size.

Integrated shape and material selection for single and multi-performance criteria

International Nuclear Information System (INIS)

Singh, Jasveer; Mirjalili, Vahid; Pasini, Damiano

2011-01-01

Research highlights: → The method of shape transformers is extended to torsional stiffness and combined load design. → The method is generalized for multi-criteria selection of shape and material. → Performance charts are presented for single and multi-objective selection of cross-section shape and material. → A four quadrant performance chart is presented to visualize the relation between objective function space and design variable space. -- Abstract: A shape and material selection method, based on the concept of shape transformers, has been recently introduced to characterize the mass efficiency of lightweight beams under bending and shear. This paper extends this method to deal with the case of torsional stiffness design, and generalize it to single and multi-crieria selection of lightweight shafts subjected to a combination of bending, shear, and torsional load. The novel feature of the paper is the useful integration of shape and material to model and visualize multi-objective selection problems. The scheme is centered on concept selection in structural design, and hinges on measures that govern the shape properties of a cross-section regardless of its size. These measures, referred as shape transformers, can classify shapes in a way similar to material classification. The procedure is exemplified by considering torsional stiffness as a constraint. The performance charts are developed for single and multi-criteria to visualize in a glance the whole range of cross-sectional shapes for each material. Each design chart is explained with a brief example.

Secondary Mathematics Pre-Service Teachers' Processes of Selection and Integration of Technology

Science.gov (United States)

Uzan, Erol

2017-01-01

This study investigated secondary mathematics pre-service teachers' (PSTs) knowledge of resources in terms of digital technologies, and explored the processes of both selection and integration of technology into their lesson plans. This study employed a case study design. Participants were six secondary mathematics PSTs who enrolled in a methods…

Allopatric integrations selectively change host transcriptomes, leading to varied expression efficiencies of exotic genes in Myxococcus xanthus.

Science.gov (United States)

Zhu, Li-Ping; Yue, Xin-Jing; Han, Kui; Li, Zhi-Feng; Zheng, Lian-Shuai; Yi, Xiu-Nan; Wang, Hai-Long; Zhang, You-Ming; Li, Yue-Zhong

2015-07-22

Exotic genes, especially clustered multiple-genes for a complex pathway, are normally integrated into chromosome for heterologous expression. The influences of insertion sites on heterologous expression and allotropic expressions of exotic genes on host remain mostly unclear. We compared the integration and expression efficiencies of single and multiple exotic genes that were inserted into Myxococcus xanthus genome by transposition and attB-site-directed recombination. While the site-directed integration had a rather stable chloramphenicol acetyl transferase (CAT) activity, the transposition produced varied CAT enzyme activities. We attempted to integrate the 56-kb gene cluster for the biosynthesis of antitumor polyketides epothilones into M. xanthus genome by site-direction but failed, which was determined to be due to the insertion size limitation at the attB site. The transposition technique produced many recombinants with varied production capabilities of epothilones, which, however, were not paralleled to the transcriptional characteristics of the local sites where the genes were integrated. Comparative transcriptomics analysis demonstrated that the allopatric integrations caused selective changes of host transcriptomes, leading to varied expressions of epothilone genes in different mutants. With the increase of insertion fragment size, transposition is a more practicable integration method for the expression of exotic genes. Allopatric integrations selectively change host transcriptomes, which lead to varied expression efficiencies of exotic genes.

Reduced and selective integration techniques in the finite element analysis of plates

International Nuclear Information System (INIS)

Hughes, T.J.R.; Cohen, M.; Haroun, M.

1978-01-01

Efforts to develop effective plate bending finite elements by reduced integration techniques are described. The basis for the development is a 'thick' plate theory in which transverse shear strains are accounted for. The variables in the theory are all kinematic, namely, displacements and independent rotations. As only C 0 continuity is required, isoparametric elements may be employed, which result in several advantages over thin plate elements. It is shown that the avoidance of shear 'locking' may be facilitated by reduced integration techniques. Both uniform and selective schemes are considered. Conditions under which selective schemes are invariant are identified, and they are found to have an advantage over uniform schemes in the present situation. It is pointed out that the present elements are not subject to the difficulties encountered by thin plate theory elements, concerning boundary conditions. For example, the polygonal approximation of curved, simply supported edges is convergent. Other topics discussed are the equivalence with mixed methods, rank deficiency, convergence criteria and useful mass 'lumping' schemes for dynamics. Numerical results for several thin plate problems indicate the high degree of accuracy attainable by the present elements. (Auth.)

Electronic signature for medical documents--integration and evaluation of a public key infrastructure in hospitals.

Science.gov (United States)

Brandner, R; van der Haak, M; Hartmann, M; Haux, R; Schmücker, P

2002-01-01

Our objectives were to determine the user-oriented and legal requirements for a Public Key Infrastructure (PKI) for electronic signatures for medical documents, and to translate these requirements into a general model for a signature system. A prototype of this model was then implemented and evaluated in clinical routine use. Analyses of documents, processes, interviews, observations, and of the available literature supplied the foundations for the development of the signature system model. Eight participants of the Department of Dermatology of the Heidelberg University Medical Center evaluated the implemented prototype from December 2000 to January 2001, during the course of an intervention study. By means of questionnaires, interviews, observations and database analyses, the usefulness and user acceptance of the electronic signature and its integration into electronic discharge letters were established. Since the major part of medical documents generated in a hospital are signature-relevant, they will require electronic signatures in the future. A PKI must meet the multitude of responsibilities and security needs required in a hospital. Also, the signature functionality must be integrated directly into the workflow surrounding document creation. A developed signature model, fulfilling user-oriented and legal requirements, was implemented using hard and software components that conform to the German Signature Law. It was integrated into the existing hospital information system of the Heidelberg University Medical Center. At the end of the intervention study, the average acceptance scores achieved were mean = 3.90; SD = 0.42 on a scale of 1 (very negative attitude) to 5 (very positive attitude) for the electronic signature procedure. Acceptance of the integration into computer-supported discharge letter writing reached mean = 3.91; SD = 0.47. On average, the discharge letters were completed 7.18 days earlier. The electronic signature is indispensable for the

Metropolitan Quantum Key Distribution with Silicon Photonics

Science.gov (United States)

Bunandar, Darius; Lentine, Anthony; Lee, Catherine; Cai, Hong; Long, Christopher M.; Boynton, Nicholas; Martinez, Nicholas; DeRose, Christopher; Chen, Changchen; Grein, Matthew; Trotter, Douglas; Starbuck, Andrew; Pomerene, Andrew; Hamilton, Scott; Wong, Franco N. C.; Camacho, Ryan; Davids, Paul; Urayama, Junji; Englund, Dirk

2018-04-01

Photonic integrated circuits provide a compact and stable platform for quantum photonics. Here we demonstrate a silicon photonics quantum key distribution (QKD) encoder in the first high-speed polarization-based QKD field tests. The systems reach composable secret key rates of 1.039 Mbps in a local test (on a 103.6-m fiber with a total emulated loss of 9.2 dB) and 157 kbps in an intercity metropolitan test (on a 43-km fiber with 16.4 dB loss). Our results represent the highest secret key generation rate for polarization-based QKD experiments at a standard telecom wavelength and demonstrate photonic integrated circuits as a promising, scalable resource for future formation of metropolitan quantum-secure communications networks.

DEVELOPMENT OF AN INTEGRATED AIR POLLUTION MAPS ON KEY PLOT OF KRASNOYARSK REGION

Directory of Open Access Journals (Sweden)

E. A. Bozhilina

2016-01-01

Full Text Available The paper suggested the construction of a comprehensive air pollution map as an example of the key area of the Krasnoyarsk Territory. To create a map developed an original technique for limiting emissions spread zones in the atmosphere from industrial plants near the cities on the basis of climatic data. The proposed method is based on taking into account the repeatability wind speed and direction and length of time of pollutants in the atmosphere. The used methods of cartographic representation – quantitative background (emissions per unit area within the zones of the potential spread of contaminants, localized diagrams (emissions and air pollution index for the city, contour lines (the value of air pollution potential. Using an integrated map allows you to specify the impact of the transfer of pollutants in the formation of the level of pollution in the city, together with the volumes and values of emissions of air pollution potential.

The evolution of phenotypic integration: How directional selection reshapes covariation in mice.

Science.gov (United States)

Penna, Anna; Melo, Diogo; Bernardi, Sandra; Oyarzabal, Maria Inés; Marroig, Gabriel

2017-10-01

Variation is the basis for evolution, and understanding how variation can evolve is a central question in biology. In complex phenotypes, covariation plays an even more important role, as genetic associations between traits can bias and alter evolutionary change. Covariation can be shaped by complex interactions between loci, and this genetic architecture can also change during evolution. In this article, we analyzed mouse lines experimentally selected for changes in size to address the question of how multivariate covariation changes under directional selection, as well as to identify the consequences of these changes to evolution. Selected lines showed a clear restructuring of covariation in their cranium and, instead of depleting their size variation, these lines increased their magnitude of integration and the proportion of variation associated with the direction of selection. This result is compatible with recent theoretical works on the evolution of covariation that take the complexities of genetic architecture into account. This result also contradicts the traditional view of the effects of selection on available covariation and suggests a much more complex view of how populations respond to selection. © 2017 The Author(s). Evolution published by Wiley Periodicals, Inc. on behalf of The Society for the Study of Evolution.

Prolonged Integration Site Selection of a Lentiviral Vector in the Genome of Human Keratinocytes.

Science.gov (United States)

Qian, Wei; Wang, Yong; Li, Rui-Fu; Zhou, Xin; Liu, Jing; Peng, Dai-Zhi

2017-03-03

BACKGROUND Lentiviral vectors have been successfully used for human skin cell gene transfer studies. Defining the selection of integration sites for retroviral vectors in the host genome is crucial in risk assessment analysis of gene therapy. However, genome-wide analyses of lentiviral integration sites in human keratinocytes, especially after prolonged growth, are poorly understood. MATERIAL AND METHODS In this study, 874 unique lentiviral vector integration sites in human HaCaT keratinocytes after long-term culture were identified and analyzed with the online tool GTSG-QuickMap and SPSS software. RESULTS The data indicated that lentiviral vectors showed integration site preferences for genes and gene-rich regions. CONCLUSIONS This study will likely assist in determining the relative risks of the lentiviral vector system and in the design of a safe lentiviral vector system in the gene therapy of skin diseases.

Low cost, small form factor, and integration as the key features for the optical component industry takeoff

Science.gov (United States)

Schiattone, Francesco; Bonino, Stefano; Gobbi, Luigi; Groppi, Angelamaria; Marazzi, Marco; Musio, Maurizio

2003-04-01

In the past the optical component market has been mainly driven by performances. Today, as the number of competitors has drastically increased, the system integrators have a wide range of possible suppliers and solutions giving them the possibility to be more focused on cost and also on footprint reduction. So, if performances are still essential, low cost and Small Form Factor issues are becoming more and more crucial in selecting components. Another evolution in the market is the current request of the optical system companies to simplify the supply chain in order to reduce the assembling and testing steps at system level. This corresponds to a growing demand in providing subassemblies, modules or hybrid integrated components: that means also Integration will be an issue in which all the optical component companies will compete to gain market shares. As we can see looking several examples offered by electronic market, to combine low cost and SFF is a very challenging task but Integration can help in achieving both features. In this work we present how these issues could be approached giving examples of some advanced solutions applied to LiNbO3 modulators. In particular we describe the progress made on automation, new materials and low cost fabrication methods for the parts. We also introduce an approach in integrating optical and electrical functionality on LiNbO3 modulators including RF driver, bias control loop, attenuator and photodiode integrated in a single device.

The study of key issues about integration of GNSS and strong-motion records for real-time earthquake monitoring

Science.gov (United States)

Tu, Rui; Zhang, Pengfei; Zhang, Rui; Liu, Jinhai

2016-08-01

This paper has studied the key issues about integration of GNSS and strong-motion records for real-time earthquake monitoring. The validations show that the consistence of the coordinate system must be considered firstly to exclude the system bias between GNSS and strong-motion. The GNSS sampling rate is suggested about 1-5 Hz, and we should give the strong-motion's baseline shift with a larger dynamic noise as its variation is very swift. The initialization time of solving the baseline shift is less than one minute, and ambiguity resolution strategy is not greatly improved the solution. The data quality is very important for the solution, we advised to use multi-frequency and multi-system observations. These ideas give an important guide for real-time earthquake monitoring and early warning by the tight integration of GNSS and strong-motion records.

An integrated knowledge-based and optimization tool for the sustainable selection of wastewater treatment process concepts

DEFF Research Database (Denmark)

Castillo, A.; Cheali, Peam; Gómez, V.

2016-01-01

The increasing demand on wastewater treatment plants (WWTPs) has involved an interest in improving the alternative treatment selection process. In this study, an integrated framework including an intelligent knowledge-based system and superstructure-based optimization has been developed and applied...... to a real case study. Hence, a multi-criteria analysis together with mathematical models is applied to generate a ranked short-list of feasible treatments for three different scenarios. Finally, the uncertainty analysis performed allows for increasing the quality and robustness of the decisions considering...... benefit and synergy is achieved when both tools are integrated because expert knowledge and expertise are considered together with mathematical models to select the most appropriate treatment alternative...

Metropolitan Quantum Key Distribution with Silicon Photonics

Directory of Open Access Journals (Sweden)

Darius Bunandar

2018-04-01

Full Text Available Photonic integrated circuits provide a compact and stable platform for quantum photonics. Here we demonstrate a silicon photonics quantum key distribution (QKD encoder in the first high-speed polarization-based QKD field tests. The systems reach composable secret key rates of 1.039 Mbps in a local test (on a 103.6-m fiber with a total emulated loss of 9.2 dB and 157 kbps in an intercity metropolitan test (on a 43-km fiber with 16.4 dB loss. Our results represent the highest secret key generation rate for polarization-based QKD experiments at a standard telecom wavelength and demonstrate photonic integrated circuits as a promising, scalable resource for future formation of metropolitan quantum-secure communications networks.

Hybrid robust model based on an improved functional link neural network integrating with partial least square (IFLNN-PLS) and its application to predicting key process variables.

Science.gov (United States)

He, Yan-Lin; Xu, Yuan; Geng, Zhi-Qiang; Zhu, Qun-Xiong

2016-03-01

In this paper, a hybrid robust model based on an improved functional link neural network integrating with partial least square (IFLNN-PLS) is proposed. Firstly, an improved functional link neural network with small norm of expanded weights and high input-output correlation (SNEWHIOC-FLNN) was proposed for enhancing the generalization performance of FLNN. Unlike the traditional FLNN, the expanded variables of the original inputs are not directly used as the inputs in the proposed SNEWHIOC-FLNN model. The original inputs are attached to some small norm of expanded weights. As a result, the correlation coefficient between some of the expanded variables and the outputs is enhanced. The larger the correlation coefficient is, the more relevant the expanded variables tend to be. In the end, the expanded variables with larger correlation coefficient are selected as the inputs to improve the performance of the traditional FLNN. In order to test the proposed SNEWHIOC-FLNN model, three UCI (University of California, Irvine) regression datasets named Housing, Concrete Compressive Strength (CCS), and Yacht Hydro Dynamics (YHD) are selected. Then a hybrid model based on the improved FLNN integrating with partial least square (IFLNN-PLS) was built. In IFLNN-PLS model, the connection weights are calculated using the partial least square method but not the error back propagation algorithm. Lastly, IFLNN-PLS was developed as an intelligent measurement model for accurately predicting the key variables in the Purified Terephthalic Acid (PTA) process and the High Density Polyethylene (HDPE) process. Simulation results illustrated that the IFLNN-PLS could significant improve the prediction performance. Copyright © 2015 ISA. Published by Elsevier Ltd. All rights reserved.

Indicators and measurement tools for health system integration: a knowledge synthesis protocol.

Science.gov (United States)

Oelke, Nelly D; Suter, Esther; da Silva Lima, Maria Alice Dias; Van Vliet-Brown, Cheryl

2015-07-29

Health system integration is a key component of health system reform with the goal of improving outcomes for patients, providers, and the health system. Although health systems continue to strive for better integration, current delivery of health services continues to be fragmented. A key gap in the literature is the lack of information on what successful integration looks like and how to measure achievement towards an integrated system. This multi-site study protocol builds on a prior knowledge synthesis completed by two of the primary investigators which identified 10 key principles that collectively support health system integration. The aim is to answer two research questions: What are appropriate indicators for each of the 10 key integration principles developed in our previous knowledge synthesis and what measurement tools are used to measure these indicators? To enhance generalizability of the findings, a partnership between Canada and Brazil was created as health system integration is a priority in both countries and they share similar contexts. This knowledge synthesis will follow an iterative scoping review process with emerging information from knowledge-user engagement leading to the refinement of research questions and study selection. This paper describes the methods for each phase of the study. Research questions were developed with stakeholder input. Indicator identification and prioritization will utilize a modified Delphi method and patient/user focus groups. Based on priority indicators, a search of the literature will be completed and studies screened for inclusion. Quality appraisal of relevant studies will be completed prior to data extraction. Results will be used to develop recommendations and key messages to be presented through integrated and end-of-grant knowledge translation strategies with researchers and knowledge-users from the three jurisdictions. This project will directly benefit policy and decision-makers by providing an easy

Workplace Integration: Key Considerations for Internationally Educated Nurses and Employers

OpenAIRE

Zubeida Ramji; Josephine Etowa

2018-01-01

Integration of internationally educated nurses (IENs) in the workplace over the long term, has not been a clear focus in nursing. The role of the employer organization in facilitating workplace integration for IENs has also not been emphasized in research. The overall aim of this paper is to highlight findings from an instrumental qualitative case study research informed by critical social theory, which examined workplace integration of IENs. The study explored what is meant by ‘integration’ ...

An Integrated DEMATEL-VIKOR Method-Based Approach for Cotton Fibre Selection and Evaluation

Science.gov (United States)

Chakraborty, Shankar; Chatterjee, Prasenjit; Prasad, Kanika

2018-01-01

Selection of the most appropriate cotton fibre type for yarn manufacturing is often treated as a multi-criteria decision-making (MCDM) problem as the optimal selection decision needs to be taken in presence of several conflicting fibre properties. In this paper, two popular MCDM methods in the form of decision making trial and evaluation laboratory (DEMATEL) and VIse Kriterijumska Optimizacija kompromisno Resenje (VIKOR) are integrated to aid the cotton fibre selection decision. DEMATEL method addresses the interrelationships between various physical properties of cotton fibres while segregating them into cause and effect groups, whereas, VIKOR method helps in ranking all the considered 17 cotton fibres from the best to the worst. The derived ranking of cotton fibre alternatives closely matches with that obtained by the past researchers. This model can assist the spinning industry personnel in the blending process while making accurate fibre selection decision when cotton fibre properties are numerous and interrelated.

Integrating care for older people with complex needs: key insights and lessons from a seven-country cross-case analysis.

Science.gov (United States)

Wodchis, Walter P; Dixon, Anna; Anderson, Geoff M; Goodwin, Nick

2015-01-01

To address the challenges of caring for a growing number of older people with a mix of both health problems and functional impairment, programmes in different countries have different approaches to integrating health and social service supports. The goal of this analysis is to identify important lessons for policy makers and service providers to enable better design, implementation and spread of successful integrated care models. This paper provides a structured cross-case synthesis of seven integrated care programmes in Australia, Canada, the Netherlands, New Zealand, Sweden, the UK and the USA. All seven programmes involved bottom-up innovation driven by local needs and included: (1) a single point of entry, (2) holistic care assessments, (3) comprehensive care planning, (4) care co-ordination and (5) a well-connected provider network. The process of achieving successful integration involves collaboration and, although the specific types of collaboration varied considerably across the seven case studies, all involved a care coordinator or case manager. Most programmes were not systematically evaluated but the two with formal external evaluations showed benefit and have been expanded. Case managers or care coordinators who support patient-centred collaborative care are key to successful integration in all our cases as are policies that provide funds and support for local initiatives that allow for bottom-up innovation. However, more robust and systematic evaluation of these initiatives is needed to clarify the 'business case' for integrated health and social care and to ensure successful generalization of local successes.

Systematic Prioritization and Integrative Analysis of Copy Number Variations in Schizophrenia Reveal Key Schizophrenia Susceptibility Genes

Science.gov (United States)

Luo, Xiongjian; Huang, Liang; Han, Leng; Luo, Zhenwu; Hu, Fang; Tieu, Roger; Gan, Lin

2014-01-01

Schizophrenia is a common mental disorder with high heritability and strong genetic heterogeneity. Common disease-common variants hypothesis predicts that schizophrenia is attributable in part to common genetic variants. However, recent studies have clearly demonstrated that copy number variations (CNVs) also play pivotal roles in schizophrenia susceptibility and explain a proportion of missing heritability. Though numerous CNVs have been identified, many of the regions affected by CNVs show poor overlapping among different studies, and it is not known whether the genes disrupted by CNVs contribute to the risk of schizophrenia. By using cumulative scoring, we systematically prioritized the genes affected by CNVs in schizophrenia. We identified 8 top genes that are frequently disrupted by CNVs, including NRXN1, CHRNA7, BCL9, CYFIP1, GJA8, NDE1, SNAP29, and GJA5. Integration of genes affected by CNVs with known schizophrenia susceptibility genes (from previous genetic linkage and association studies) reveals that many genes disrupted by CNVs are also associated with schizophrenia. Further protein-protein interaction (PPI) analysis indicates that protein products of genes affected by CNVs frequently interact with known schizophrenia-associated proteins. Finally, systematic integration of CNVs prioritization data with genetic association and PPI data identifies key schizophrenia candidate genes. Our results provide a global overview of genes impacted by CNVs in schizophrenia and reveal a densely interconnected molecular network of de novo CNVs in schizophrenia. Though the prioritized top genes represent promising schizophrenia risk genes, further work with different prioritization methods and independent samples is needed to confirm these findings. Nevertheless, the identified key candidate genes may have important roles in the pathogenesis of schizophrenia, and further functional characterization of these genes may provide pivotal targets for future therapeutics and

Logistics Service Provider Selection through an Integrated Fuzzy Multicriteria Decision Making Approach

OpenAIRE

Gülşen Akman; Kasım Baynal

2014-01-01

Nowadays, the demand of third-party logistics provider becomes an increasingly important issue for companies to improve their customer service and to decrease logistics costs. This paper presents an integrated fuzzy approach for the evaluation and selection of 3rd party logistics service providers. This method consists of two techniques: (1) use fuzzy analytic hierarchy process to identify weights of evaluation criteria; (2) apply fuzzy technique for order preference by similarity to ideal so...

Key Issues for Seamless Integrated Chemistry–Meteorology Modeling

Science.gov (United States)

Online coupled meteorology–atmospheric chemistry models have greatly evolved in recent years. Although mainly developed by the air quality modeling community, these integrated models are also of interest for numerical weather prediction and climate modeling, as they can con...

IMPACT_S: integrated multiprogram platform to analyze and combine tests of selection.

Directory of Open Access Journals (Sweden)

Emanuel Maldonado

Full Text Available Among the major goals of research in evolutionary biology are the identification of genes targeted by natural selection and understanding how various regimes of evolution affect the fitness of an organism. In particular, adaptive evolution enables organisms to adapt to changing ecological factors such as diet, temperature, habitat, predatory pressures and prey abundance. An integrative approach is crucial for the identification of non-synonymous mutations that introduce radical changes in protein biochemistry and thus in turn influence the structure and function of proteins. Performing such analyses manually is often a time-consuming process, due to the large number of statistical files generated from multiple approaches, especially when assessing numerous taxa and/or large datasets. We present IMPACT_S, an easy-to-use Graphical User Interface (GUI software, which rapidly and effectively integrates, filters and combines results from three widely used programs for assessing the influence of selection: Codeml (PAML package, Datamonkey and TreeSAAP. It enables the identification and tabulation of sites detected by these programs as evolving under the influence of positive, neutral and/or negative selection in protein-coding genes. IMPACT_S further facilitates the automatic mapping of these sites onto the three-dimensional structures of proteins. Other useful tools incorporated in IMPACT_S include Jmol, Archaeopteryx, Gnuplot, PhyML, a built-in Swiss-Model interface and a PDB downloader. The relevance and functionality of IMPACT_S is shown through a case study on the toxicoferan-reptilian Cysteine-rich Secretory Proteins (CRiSPs. IMPACT_S is a platform-independent software released under GPLv3 license, freely available online from http://impact-s.sourceforge.net.

IMPACT_S: integrated multiprogram platform to analyze and combine tests of selection.

Science.gov (United States)

Maldonado, Emanuel; Sunagar, Kartik; Almeida, Daniela; Vasconcelos, Vitor; Antunes, Agostinho

2014-01-01

Among the major goals of research in evolutionary biology are the identification of genes targeted by natural selection and understanding how various regimes of evolution affect the fitness of an organism. In particular, adaptive evolution enables organisms to adapt to changing ecological factors such as diet, temperature, habitat, predatory pressures and prey abundance. An integrative approach is crucial for the identification of non-synonymous mutations that introduce radical changes in protein biochemistry and thus in turn influence the structure and function of proteins. Performing such analyses manually is often a time-consuming process, due to the large number of statistical files generated from multiple approaches, especially when assessing numerous taxa and/or large datasets. We present IMPACT_S, an easy-to-use Graphical User Interface (GUI) software, which rapidly and effectively integrates, filters and combines results from three widely used programs for assessing the influence of selection: Codeml (PAML package), Datamonkey and TreeSAAP. It enables the identification and tabulation of sites detected by these programs as evolving under the influence of positive, neutral and/or negative selection in protein-coding genes. IMPACT_S further facilitates the automatic mapping of these sites onto the three-dimensional structures of proteins. Other useful tools incorporated in IMPACT_S include Jmol, Archaeopteryx, Gnuplot, PhyML, a built-in Swiss-Model interface and a PDB downloader. The relevance and functionality of IMPACT_S is shown through a case study on the toxicoferan-reptilian Cysteine-rich Secretory Proteins (CRiSPs). IMPACT_S is a platform-independent software released under GPLv3 license, freely available online from http://impact-s.sourceforge.net.

Research on key technology of planning and design for AC/DC hybrid distribution network

Science.gov (United States)

Shen, Yu; Wu, Guilian; Zheng, Huan; Deng, Junpeng; Shi, Pengjia

2018-04-01

With the increasing demand of DC generation and DC load, the development of DC technology, AC and DC distribution network integrating will become an important form of future distribution network. In this paper, the key technology of planning and design for AC/DC hybrid distribution network is proposed, including the selection of AC and DC voltage series, the design of typical grid structure and the comprehensive evaluation method of planning scheme. The research results provide some ideas and directions for the future development of AC/DC hybrid distribution network.

An integrated approach to selecting materials for fuel cladding in advanced high-temperature reactors

Energy Technology Data Exchange (ETDEWEB)

Rangacharyulu, C., E-mail: chary.r@usask.ca [Univ. of Saskatchewan, Saskatoon, SK (Canada); Guzonas, D.A.; Pencer, J.; Nava-Dominguez, A.; Leung, L.K.H. [Atomic Energy of Canada Limited, Chalk River, ON (Canada)

2014-07-01

An integrated approach has been developed for selection of fuel cladding materials for advanced high-temperature reactors. Reactor physics, thermalhydraulic and material analyses are being integrated in a systematic study comparing various candidate fuel-cladding alloys. The analyses established the axial and radial neutron fluxes, power distributions, axial and radial temperature distributions, rates of defect formation and helium production using AECL analytical toolsets and experimentally measured corrosion rates to optimize the material composition for fuel cladding. The project has just been initiated at University of Saskatchewan. Some preliminary results of the analyses are presented together with the path forward for the project. (author)

Graduate Curriculum for Biological Information Specialists: A Key to Integration of Scale in Biology

Directory of Open Access Journals (Sweden)

Carole L. Palmer

2007-12-01

Full Text Available Scientific data problems do not stand in isolation. They are part of a larger set of challenges associated with the escalation of scientific information and changes in scholarly communication in the digital environment. Biologists in particular are generating enormous sets of data at a high rate, and new discoveries in the biological sciences will increasingly depend on the integration of data across multiple scales. This work will require new kinds of information expertise in key areas. To build this professional capacity we have developed two complementary educational programs: a Biological Information Specialist (BIS masters degree and a concentration in Data Curation (DC. We believe that BISs will be central in the development of cyberinfrastructure and information services needed to facilitate interdisciplinary and multi-scale science. Here we present three sample cases from our current research projects to illustrate areas in which we expect information specialists to make important contributions to biological research practice.

Enzyme technology: Key to selective biorefining

DEFF Research Database (Denmark)

Meyer, Anne S.

2014-01-01

to the reaction is a unique trait of enzyme catalysis. Since enzyme selectivity means that a specific reaction is catalysed between particular species to produce definite products, enzymes are particularly fit for converting specific compounds in mixed biomass streams. Since enzymes are protein molecules...... their rational use in biorefinery processes requires an understanding of the basic features of enzymes and reaction traits with respect to specificity, kinetics, reaction optima, stability and structure-function relations – we are now at a stage where it is possible to use nature’s enzyme structures as starting...... point and then improve the functional traits by targeted mutation of the protein. The talk will display some of our recent hypotheses related to enzyme action, recently obtained results within knowledge-based enzyme improvements as well as cast light on research methods used in optimizing enzyme...

An integrated multi-criteria decision-making methodology for conveyor system selection

Directory of Open Access Journals (Sweden)

Pairat Jiamruangjarus

2016-12-01

Full Text Available Material handling equipment (MHE is important for every industry because it has an effect on the productivity of manufacturing. Conveyor systems are presently one popular type of MHE. This paper presents an integration of the analytic network process (ANP with the benefits, opportunities, costs and risk (BOCR model in order to select the best conveyor system. The proposed model established a network with four merits, six strategies criteria, and twenty six sub-criteria with four alternatives (present, roller conveyor, chain conveyor, and monorail. The ANP is to determine the relative weights of an evaluative criteria and decision alternatives. Therefore, the final ranking of the alternatives are calculated by synthesizing the score of each alternative under BOCR. The results showed that the best alternative under all five methods is the chain conveyor. These research results can be easily applied, adapted and used to improve performance of selecting the conveyer system in small and medium enterprises through large industries.

High-Speed Large-Alphabet Quantum Key Distribution Using Photonic Integrated Circuits

Science.gov (United States)

2014-01-28

polarizing beam splitter, TDC: time-to-digital converter. Extra&loss& photon/bin frame size QSER secure bpp ECC secure&key&rate& none& 0.0031 64 14...to-digital converter. photon/frame frame size QSER secure bpp ECC secure&key& rate& 1.3 16 9.5 % 2.9 layered LDPC 7.3&Mbps& Figure 24: Operating

Integrated assessment of climate change

International Nuclear Information System (INIS)

Morgan, M.G.

1994-01-01

Many researchers are working on all the separate parts of the climate problem. The objective of integrated assessment is to put the results from this work together in order to look carefully at the big picture so as to: (1) keep a proper sense of perspective about the problem, since climate change will occur in the presence of many other natural and human changes; (2) develop the understanding necessary to support informed decision making by many different key public and private actors around the world; and (3) assure that the type and mix of climate-related research that is undertaken will be as useful as possible to decisions makers in both the near and long term. This paper outlines a set of design guidelines for formulating integrated assessment programs and projects and then outlines some of the current problems and opportunities. Selected points are illustrated by drawing on results from the integrated assessment research now in progress at Carnegie Mellon University

Feasibility of Integration of Selected Aspects of (CBA) Chemistry, (CHEMS) Chemistry and (PSSC) Physics into a Two Year Physical Science Sequence.

Science.gov (United States)

Fiasca, Michael Aldo

Compared, for selected outcomes, were integrated chemistry-physics courses with chemistry and physics courses taught separately. Three classes studying integrated Physical Science Study Committee (PSSC)-Chemical Bond Approach (CBA), and three classes studying integrated Physical Science Study Committee-Chemical Education Materials Study (CHEMS)…

The INGECAD multidisciplinary integrated computer aided engineering system

International Nuclear Information System (INIS)

Kisielewicz, L.T.

1989-01-01

The purpose of this paper is to define the key criteria of an integrated CAE system, and to discuss the solution developed by Ingevision to match these criteria. An information flow model of process plant engineering is presented as a background to the key criteria of CAE systems. This model includes multidisciplinary interfaces and project changes up to the as-built stage. The key quality criteria of CAE systems correspond to managerial issues, such as project control, to technical issues, consistency and quality assurance, and to economical issues, such as cost optimization. The INGECAD system answers these criteria with a tripod nucleus underlying a set of specialized applications. The nucleus includes a Data Base Management System, basic Graphical Tools, and a Decision Support System. The paper overviews the different modules of the INGECAD system emphasizing the general architecture and the basic tools. Specific examples are developed in functional design, cost optimized items selection, and semi-automated routing of piping system. These examples are not intended to illustrate exhaustively the capabilities of the INGECAD system, but rather to highlight some of the advantages the multidisciplinary integration of the system provides to the users. (orig./HP)

Integrated Behavior Therapy for Selective Mutism: a randomized controlled pilot study.

Science.gov (United States)

Bergman, R Lindsey; Gonzalez, Araceli; Piacentini, John; Keller, Melody L

2013-10-01

To evaluate the feasibility, acceptability, and preliminary efficacy of a novel behavioral intervention for reducing symptoms of selective mutism and increasing functional speech. A total of 21 children ages 4 to 8 with primary selective mutism were randomized to 24 weeks of Integrated Behavior Therapy for Selective Mutism (IBTSM) or a 12-week Waitlist control. Clinical outcomes were assessed using blind independent evaluators, parent-, and teacher-report, and an objective behavioral measure. Treatment recipients completed a three-month follow-up to assess durability of treatment gains. Data indicated increased functional speaking behavior post-treatment as rated by parents and teachers, with a high rate of treatment responders as rated by blind independent evaluators (75%). Conversely, children in the Waitlist comparison group did not experience significant improvements in speaking behaviors. Children who received IBTSM also demonstrated significant improvements in number of words spoken at school compared to baseline, however, significant group differences did not emerge. Treatment recipients also experienced significant reductions in social anxiety per parent, but not teacher, report. Clinical gains were maintained over 3 month follow-up. IBTSM appears to be a promising new intervention that is efficacious in increasing functional speaking behaviors, feasible, and acceptable to parents and teachers. Copyright © 2013 Elsevier Ltd. All rights reserved.

Integrated circuit microsensor for selectively detection nitrogen dioxide and diisopropyl methylphosphonate

Energy Technology Data Exchange (ETDEWEB)

Kolesar, E.S. Jr. (Air Force Inst. of Technology, Dept. of Electrical and Computer Engineering, Wright-Patterson Air Force Base, Dayton, OH (United States)); Brothers, C.P. Jr. (Air Force Inst. of Technology, Dept. of Electrical and Computer Engineering, Wright-Patterson Air Force Base, Dayton, OH (United States)); Howe, C.P. (Air Force Inst. of Technology, Dept. of Electrical and Computer Engineering, Wright-Patterson Air Force Base, Dayton, OH (United States)); Jenkins, T.J. (Air Force Inst. of Technology, Dept. of Electrical and Computer Engineering, Wright-Patterson Air Force Base, Dayton, OH (United States)); Moosey, A.T. (Air Force Inst. of Technology, Dept. of Electrical and Computer Engineering, Wright-Patterson Air Force Base, Dayton, OH (United States)); Shin, J.E. (Air Force Inst. of Technology, Dept. of Electrical and Computer Engineering, Wright-Patterson Air Force Base, Dayton, OH (United States)); Wiseman, J.M. (Air Force Inst. of Technology, Dept. of Electrical an

1992-11-20

A novel gas-sensitive microsensor, known as the interdigitated gate electrode field effect transistor (IGEFET), was realized by selectively depositing a chemically-active, electron-beam evaporated copper phthalocyanine (CuPc) thin film onto an integrated circuit (IC). When isothermally operated at 150 C, the microsensor can selectively and reversibly detect parts-per-billion concentration levels of nitrogen dioxide (NO[sub 2]) and diisopropyl methylphosphonate (DIMP). The selectivity feature of the microsensor was established by operating it with a 5 V peak amplitude, 2 [mu]s duration, 1000 Hz repetition frequency pulse, and then analyzing its time- and frequency-domain responses. The envelopes associated with the normalized-difference Fourier transform magnitude spectra, and their derivatives, reveal features which unambiguously distinguish the NO[sub 2] and DIMP challenge gas responses. Furthermore, the area beneath each response envelope may correspondingly be interpreted as the microsensor's sensitivity for a specific challenge gas concentration. Scanning electron microscopy (SEM) was used to characterize the morphology of the CuPc thin film. Additionally, infrared (IR) spectroscopy was employed to verify the [alpha]- and [beta]-phases of the sublimed CuPc thin films and to study the NO[sub 2]- and DIMP-CuPc interactions. (orig.)

Space division multiplexing chip-to-chip quantum key distribution

DEFF Research Database (Denmark)

Bacco, Davide; Ding, Yunhong; Dalgaard, Kjeld

2017-01-01

nodes of the quantum keys to their respective destinations. In this paper we present an experimental demonstration of a photonic integrated silicon chip quantum key distribution protocols based on space division multiplexing (SDM), through multicore fiber technology. Parallel and independent quantum...

Key Challenges and Opportunities Associated with the Use of In Vitro Models to Detect Human DILI: Integrated Risk Assessment and Mitigation Plans

Directory of Open Access Journals (Sweden)

Franck A. Atienzar

2016-01-01

Full Text Available Drug-induced liver injury (DILI is a major cause of late-stage clinical drug attrition, market withdrawal, black-box warnings, and acute liver failure. Consequently, it has been an area of focus for toxicologists and clinicians for several decades. In spite of considerable efforts, limited improvements in DILI prediction have been made and efforts to improve existing preclinical models or develop new test systems remain a high priority. While prediction of intrinsic DILI has improved, identifying compounds with a risk for idiosyncratic DILI (iDILI remains extremely challenging because of the lack of a clear mechanistic understanding and the multifactorial pathogenesis of idiosyncratic drug reactions. Well-defined clinical diagnostic criteria and risk factors are also missing. This paper summarizes key data interpretation challenges, practical considerations, model limitations, and the need for an integrated risk assessment. As demonstrated through selected initiatives to address other types of toxicities, opportunities exist however for improvement, especially through better concerted efforts at harmonization of current, emerging and novel in vitro systems or through the establishment of strategies for implementation of preclinical DILI models across the pharmaceutical industry. Perspectives on the incorporation of newer technologies and the value of precompetitive consortia to identify useful practices are also discussed.

Detection vs. selection: integration of genetic, epigenetic and environmental cues in fluctuating environments.

Science.gov (United States)

McNamara, John M; Dall, Sasha R X; Hammerstein, Peter; Leimar, Olof

2016-10-01

There are many inputs during development that influence an organism's fit to current or upcoming environments. These include genetic effects, transgenerational epigenetic influences, environmental cues and developmental noise, which are rarely investigated in the same formal framework. We study an analytically tractable evolutionary model, in which cues are integrated to determine mature phenotypes in fluctuating environments. Environmental cues received during development and by the mother as an adult act as detection-based (individually observed) cues. The mother's phenotype and a quantitative genetic effect act as selection-based cues (they correlate with environmental states after selection). We specify when such cues are complementary and tend to be used together, and when using the most informative cue will predominate. Thus, we extend recent analyses of the evolutionary implications of subsets of these effects by providing a general diagnosis of the conditions under which detection and selection-based influences on development are likely to evolve and coexist. © 2016 John Wiley & Sons Ltd/CNRS.

Integral or integrated marketing

Directory of Open Access Journals (Sweden)

Davčik Nebojša

2006-01-01

Full Text Available Marketing theorists and experts try to develop business efficient organization and to get marketing performance at higher, business integrated level since its earliest beginnings. The core issue in this paperwork is the dialectic and practical approach dilemma should we develop integrated or integral marketing approach in the organization. The presented company cases as well as dialectic and functional explanations of this dilemma clearly shows that integrated marketing is narrower approach than integral marketing if we take as focal point new, unique and completed entity. In the integration the essence is in getting different parts together, which do not have to make necessary the new entity. The key elements in the definition of the integral marketing are necessity and holistic, e.g. necessity to develop new, holistic entity.

Performance-Based Technology Selection Filter description report. INEL Buried Waste Integrated Demonstration System Analysis project

Energy Technology Data Exchange (ETDEWEB)

O`Brien, M.C.; Morrison, J.L.; Morneau, R.A.; Rudin, M.J.; Richardson, J.G.

1992-05-01

A formal methodology has been developed for identifying technology gaps and assessing innovative or postulated technologies for inclusion in proposed Buried Waste Integrated Demonstration (BWID) remediation systems. Called the Performance-Based Technology Selection Filter, the methodology provides a formalized selection process where technologies and systems are rated and assessments made based on performance measures, and regulatory and technical requirements. The results are auditable, and can be validated with field data. This analysis methodology will be applied to the remedial action of transuranic contaminated waste pits and trenches buried at the Idaho National Engineering Laboratory (INEL).

Evaluation and selection of energy technologies using an integrated graph theory and analytic hierarchy process methods

Directory of Open Access Journals (Sweden)

P. B. Lanjewar

2016-06-01

Full Text Available The evaluation and selection of energy technologies involve a large number of attributes whose selection and weighting is decided in accordance with the social, environmental, technical and economic framework. In the present work an integrated multiple attribute decision making methodology is developed by combining graph theory and analytic hierarchy process methods to deal with the evaluation and selection of energy technologies. The energy technology selection attributes digraph enables a quick visual appraisal of the energy technology selection attributes and their interrelationships. The preference index provides a total objective score for comparison of energy technologies alternatives. Application of matrix permanent offers a better appreciation of the considered attributes and helps to analyze the different alternatives from combinatorial viewpoint. The AHP is used to assign relative weights to the attributes. Four examples of evaluation and selection of energy technologies are considered in order to demonstrate and validate the proposed method.

Key on demand (KoD) for software-defined optical networks secured by quantum key distribution (QKD).

Science.gov (United States)

Cao, Yuan; Zhao, Yongli; Colman-Meixner, Carlos; Yu, Xiaosong; Zhang, Jie

2017-10-30

Software-defined optical networking (SDON) will become the next generation optical network architecture. However, the optical layer and control layer of SDON are vulnerable to cyberattacks. While, data encryption is an effective method to minimize the negative effects of cyberattacks, secure key interchange is its major challenge which can be addressed by the quantum key distribution (QKD) technique. Hence, in this paper we discuss the integration of QKD with WDM optical networks to secure the SDON architecture by introducing a novel key on demand (KoD) scheme which is enabled by a novel routing, wavelength and key assignment (RWKA) algorithm. The QKD over SDON with KoD model follows two steps to provide security: i) quantum key pools (QKPs) construction for securing the control channels (CChs) and data channels (DChs); ii) the KoD scheme uses RWKA algorithm to allocate and update secret keys for different security requirements. To test our model, we define a security probability index which measures the security gain in CChs and DChs. Simulation results indicate that the security performance of CChs and DChs can be enhanced by provisioning sufficient secret keys in QKPs and performing key-updating considering potential cyberattacks. Also, KoD is beneficial to achieve a positive balance between security requirements and key resource usage.

Selected area growth integrated wavelength converter based on PD-EAM optical logic gate

International Nuclear Information System (INIS)

Niu Bin; Zhou Daibing; Zhang Can; Liang Song; Lu Dan; Zhao Lingjuan; Wang Wei; Qiu Jifang; Wu Jian

2014-01-01

A selected area growth wavelength converter based on a PD-EAM optical logic gate for WDM application is presented, integrating an EML transmitter and a SOA-PD receiver. The design, fabrication, and DC characters were analyzed. A 2 Gb/s NRZ signal based on the C-band wavelength converted to 1555 nm with the highest extinction ratio of 7 dB was achieved and wavelength converted eye diagrams with eyes opened were presented. (semiconductor devices)

Bringing the Sallen-Key Biquad back to work

DEFF Research Database (Denmark)

Gaunholt, Hans; Guldbrandsen, Birthe

1996-01-01

the Sallen-Key biquad even in the high-Q case with reasonable sensitivities. The method is based on the unity gain version of the biquad and as unity gain buffer amplifiers are readily manufactured in integrated circuit technology the results may be very useful in the fabrication of integrated analog filters...

Meta-Analysis of DNA Tumor-Viral Integration Site Selection Indicates a Role for Repeats, Gene Expression and Epigenetics

Directory of Open Access Journals (Sweden)

Janet M. Doolittle-Hall

2015-11-01

Full Text Available Oncoviruses cause tremendous global cancer burden. For several DNA tumor viruses, human genome integration is consistently associated with cancer development. However, genomic features associated with tumor viral integration are poorly understood. We sought to define genomic determinants for 1897 loci prone to hosting human papillomavirus (HPV, hepatitis B virus (HBV or Merkel cell polyomavirus (MCPyV. These were compared to HIV, whose enzyme-mediated integration is well understood. A comprehensive catalog of integration sites was constructed from the literature and experimentally-determined HPV integration sites. Features were scored in eight categories (genes, expression, open chromatin, histone modifications, methylation, protein binding, chromatin segmentation and repeats and compared to random loci. Random forest models determined loci classification and feature selection. HPV and HBV integrants were not fragile site associated. MCPyV preferred integration near sensory perception genes. Unique signatures of integration-associated predictive genomic features were detected. Importantly, repeats, actively-transcribed regions and histone modifications were common tumor viral integration signatures.

KeyPathwayMiner 4.0

DEFF Research Database (Denmark)

Alcaraz, Nicolas; Pauling, Josch; Batra, Richa

2014-01-01

release of KeyPathwayMiner (version 4.0) that is not limited to analyses of single omics data sets, e.g. gene expression, but is able to directly combine several different omics data types. Version 4.0 can further integrate existing knowledge by adding a search bias towards sub-networks that contain...... (avoid) genes provided in a positive (negative) list. Finally the new release now also provides a set of novel visualization features and has been implemented as an app for the standard bioinformatics network analysis tool: Cytoscape. CONCLUSION: With KeyPathwayMiner 4.0, we publish a Cytoscape app...

Towards integrated biorefinery from dried distillers grains: Selective extraction of pentoses using dilute acid hydrolysis

International Nuclear Information System (INIS)

Fonseca, Dania A.; Lupitskyy, Robert; Timmons, David; Gupta, Mayank; Satyavolu, Jagannadh

2014-01-01

The abundant availability and high level of hemicellulose content make dried distillers grains (DDG) an attractive feedstock for production of pentoses (C5) and conversion of C5 to bioproducts. One target of this work was to produce a C5 extract (hydrolyzate) with high yield and purity with a low concentration of C5 degradation products. A high selectivity towards pentoses was achieved using dilute acid hydrolysis of DDG in a percolation reactor with liquid recirculation. Pretreatment of starting material using screening and ultrasonication resulted in fractional increase of the pentose yield by 42%. A 94% yield of pentoses on the DDG (280.9 g kg −1 ) was obtained. Selective extraction of individual pentoses has been achieved by using a 2-stage hydrolysis process, resulting in arabinose-rich (arabinose 81.5%) and xylose-rich (xylose 85.2%) streams. A broader impact of this work is towards an Integrated Bio-Refinery based on DDG – for production of biofuels, biochemical intermediates, and other bioproducts. - Highlights: • A process for selective extraction of pentoses from DDG was presented as a part of integrated biorefinery approach. • The selectivity for pentoses was high using dilute acid hydrolysis in a percolation reactor with liquid recirculation. • Pretreatment of DDG using screening and ultrasonication resulted in fractional increase of the pentose yield by 42 %. • A 94% yield in pentoses (280.9 g kg −1 of DDG) was obtained. • A 2-stage hydrolysis process, developed to extract individual pentoses, resulted in arabinose and xylose rich streams

Evaluation and selection of open-source EMR software packages based on integrated AHP and TOPSIS.

Science.gov (United States)

Zaidan, A A; Zaidan, B B; Al-Haiqi, Ahmed; Kiah, M L M; Hussain, Muzammil; Abdulnabi, Mohamed

2015-02-01

Evaluating and selecting software packages that meet the requirements of an organization are difficult aspects of software engineering process. Selecting the wrong open-source EMR software package can be costly and may adversely affect business processes and functioning of the organization. This study aims to evaluate and select open-source EMR software packages based on multi-criteria decision-making. A hands-on study was performed and a set of open-source EMR software packages were implemented locally on separate virtual machines to examine the systems more closely. Several measures as evaluation basis were specified, and the systems were selected based a set of metric outcomes using Integrated Analytic Hierarchy Process (AHP) and TOPSIS. The experimental results showed that GNUmed and OpenEMR software can provide better basis on ranking score records than other open-source EMR software packages. Copyright © 2014 Elsevier Inc. All rights reserved.

Key factors of case management interventions for frequent users of healthcare services: a thematic analysis review.

Science.gov (United States)

Hudon, Catherine; Chouinard, Maud-Christine; Lambert, Mireille; Diadiou, Fatoumata; Bouliane, Danielle; Beaudin, Jérémie

2017-10-22

The aim of this paper was to identify the key factors of case management (CM) interventions among frequent users of healthcare services found in empirical studies of effectiveness. Thematic analysis review of CM studies. We built on a previously published review that aimed to report the effectiveness of CM interventions for frequent users of healthcare services, using the Medline, Scopus and CINAHL databases covering the January 2004-December 2015 period, then updated to July 2017, with the keywords 'CM' and 'frequent use'. We extracted factors of successful (n=7) and unsuccessful (n=6) CM interventions and conducted a mixed thematic analysis to synthesise findings. Chaudoir's implementation of health innovations framework was used to organise results into four broad levels of factors: (1) ,environmental/organisational level, (2) practitioner level, (3) patient level and (4) programme level. Access to, and close partnerships with, healthcare providers and community services resources were key factors of successful CM interventions that should target patients with the greatest needs and promote frequent contacts with the healthcare team. The selection and training of the case manager was also an important factor to foster patient engagement in CM. Coordination of care, self-management support and assistance with care navigation were key CM activities. The main issues reported by unsuccessful CM interventions were problems with case finding or lack of care integration. CM interventions for frequent users of healthcare services should ensure adequate case finding processes, rigorous selection and training of the case manager, sufficient intensity of the intervention, as well as good care integration among all partners. Other studies could further evaluate the influence of contextual factors on intervention impacts. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted

Development of generic key performance indicators for PMBOK® using a 3D project integration model

Directory of Open Access Journals (Sweden)

Craig Langston

2013-12-01

Full Text Available Since Martin Barnes’ so-called ‘iron triangle’ circa 1969, much debate has occurred over how best to describe the fundamental constraints that underpin project success. This paper develops a 3D project integration model for PMBOK® comprising core constraints of scope, cost, time and risk as a basis to propose six generic key performance indicators (KPIs that articulate successful project delivery. These KPIs are defined as value, efficiency, speed, innovation, complexity and impact and can each be measured objectively as ratios of the core constraints. An overall KPI (denoted as s3/ctr is also derived. The aim in this paper is to set out the case for such a model and to demonstrate how it can be employed to assess the performance of project teams in delivering successful outcomes at various stages in the project life cycle. As part of the model’s development, a new PMBOK® knowledge area concerning environmental management is advanced.

Cryptographic Key Management System

Energy Technology Data Exchange (ETDEWEB)

No, author

2014-02-21

This report summarizes the outcome of U.S. Department of Energy (DOE) contract DE-OE0000543, requesting the design of a Cryptographic Key Management System (CKMS) for the secure management of cryptographic keys for the energy sector infrastructure. Prime contractor Sypris Electronics, in collaboration with Oak Ridge National Laboratories (ORNL), Electric Power Research Institute (EPRI), Valicore Technologies, and Purdue University's Center for Education and Research in Information Assurance and Security (CERIAS) and Smart Meter Integration Laboratory (SMIL), has designed, developed and evaluated the CKMS solution. We provide an overview of the project in Section 3, review the core contributions of all contractors in Section 4, and discuss bene ts to the DOE in Section 5. In Section 6 we describe the technical construction of the CKMS solution, and review its key contributions in Section 6.9. Section 7 describes the evaluation and demonstration of the CKMS solution in different environments. We summarize the key project objectives in Section 8, list publications resulting from the project in Section 9, and conclude with a discussion on commercialization in Section 10 and future work in Section 11.

Towards Integrating Realities

DEFF Research Database (Denmark)

Henriksen, Lars Bo

2017-01-01

The pragmatic constructivist approach provides us with a social science theory, the theory of reality, and its associated method, the conceptualising method. A key aspect in both the theory of reality and its associated conceptualising method is on the necessity of integratingfour dimensionsof...... conceptualisation of the process of integration is itself not analysed or conceptualised to the same substantive extent as are the other elements ofthe theory of reality.The key questionaddressed here thereforebecomes: how might we betteranalyse and describe this process of integration? To address this question......, Iidentify, albeit in skeletal outline,usefulsocial theoreticalcorrespondences between Arendt’s conceptualisation of action in The Human Condition(1958) and key attributes ofthe theory of reality, which, Iclaim, couldpossibly guide an entry into the ‘how’ of this elusive integration process....

Evaluation of aseismic integrity in the HTTR core-bottom structure. V. On the static and dynamic behavior of graphite HTTR key-keyway structures

International Nuclear Information System (INIS)

Futakawa, M.; Iyoku, T.

1996-01-01

For pt.IV see ibid., vol.154, p.83-95, 1995. The graphite components in high temperature gas-cooled reactors are connected to each other through a key-keyway structure that has gaps between the key and the keyway to accommodate thermal expansion. Because a dynamic load concentrates on the key-keyway structure during earthquakes, it is considered to be a crucial element for assessing the integrity of the graphite components. A combination of experiments and analyses was employed to investigate the dynamic behavior of the key-keyway structure, i.e. the equivalent stiffness associated with vibrational characteristics of the graphite components and the stress distribution under dynamic loading. The experiments were performed using a graphite scale model and a dynamic photo-elastic method. The analysis was carried out using the finite element method (FEM) code ABAQUS, taking account of the contact behavior between the key and the keyway. The following conclusions were derived. (1) The equivalent stiffness of the key-keyway structure shows nonlinearity, owing to the contact deformation. (2) The equivalent stiffness evaluated by the FEM analysis, taking account of the non-linear contact deformation, is applicable for predicting the vibrational characteristics of the key-keyway structure. (3) The stress concentration under dynamic loading is lower than or nearly equal to that under static loading. The maximum stress concentration of the seismic load can be sufficiently evaluated under static loading conditions. (orig.)

Integrated Monitoring System for Durability Assessment of Concrete Bridges

Directory of Open Access Journals (Sweden)

Cristian-Claudiu Comisu

2005-01-01

Full Text Available An ageing and deteriorating bridge stock presents the bridge owners with the growing challenge of maintaining the structures at a satisfactory level of safety, performance and aesthetic appearance within the allocated budgets. This task calls for optimized bridge management based on efficient methods of selecting technical and economical optimal maintenance and rehabilitation strategies. One of the crucial points in the assessment of the current condition and future development and performance. Selecting the optimal maintenance and rehabilitation strategy within the actual budget is a key point in bridge management for which an accurate assessment of performance and deterioration rate is necessary. For this assessment, the use of integrated monitoring system has several advantages compared to the traditional approach of scattered visual inspections combined with occasional on site testing with portable equipment and laboratory testing of collected samples. For this reason, attention is more focusing on the development of permanent integrated monitoring system for durability assessment of concrete bridges. It is estimated that with the implementation of such integrated monitoring systems, it should be possible to reduce the operating costs of inspections and maintenance by 25% and the operator of the structures will be able to take protective actions before damaging processes start. This paper indentifies the main bridge owner requirements to integrated monitoring systems and outlines how monitoring systems may be used for performance and deterioration rate assessment to establish a better basis for selecting the optimal maintenance and rehabilitation strategy.

Multi-data integration of exploration criteria and selection of prospecting targets

International Nuclear Information System (INIS)

Dechang, L.; Jingke, Z.; Maorong, S.; Guojuan, W.

1991-01-01

In this paper based on the analysis of the exploration criteria for Shengyuan Basin-a uranium ore field, the multi-data integration and information extraction of exploration criteria are carried out on computer and image processing system so that the areas with best combinations of exploration criteria are directly displayed on the screen. Six prospecting targets are selected through the field examination. Shengyuan basin in Jiangxi province is a uranium-producing, Jurassic Cretaceous volcanic-sedimentary basin with an area of about 400 sq km. Its basement consists of Sinian-Cambrian rocks with Caledonian granites intruded. Several uranium deposits, occurrences and anomalies were discovered over the basin region which, therefore, becomes a very important uranium ore field in China

The Key to School Security.

Science.gov (United States)

Hotle, Dan

1993-01-01

In addition to legislative accessibility requirements, other security issues facing school administrators who select a security system include the following: access control; user friendliness; durability or serviceability; life safety precautions; possibility of vandalism, theft, and tampering; and key control. Offers steps to take in considering…

Key handling in wireless sensor networks

International Nuclear Information System (INIS)

Li, Y; Newe, T

2007-01-01

With the rapid growth of Wireless Sensor Networks (WSNs), many advanced application areas have received significant attention. However, security will be an important factor for their full adoption. Wireless sensor nodes pose unique challenges and as such traditional security protocols, used in traditional networks cannot be applied directly. Some new protocols have been published recently with the goal of providing both privacy of data and authentication of sensor nodes for WSNs. Such protocols can employ private-key and/or public key cryptographic algorithms. Public key algorithms hold the promise of simplifying the network infrastructure required to provide security services such as: privacy, authentication and non-repudiation, while symmetric algorithms require less processing power on the lower power wireless node. In this paper a selection of key establishment/agreement protocols are reviewed and they are broadly divided into two categories: group key agreement protocols and pair-wise key establishment protocols. A summary of the capabilities and security related services provided by each protocol is provided

Key handling in wireless sensor networks

Energy Technology Data Exchange (ETDEWEB)

Li, Y; Newe, T [Optical Fibre Sensors Research Centre, Department of Electronic and Computer Engineering, University of Limerick, Limerick (Ireland)

2007-07-15

With the rapid growth of Wireless Sensor Networks (WSNs), many advanced application areas have received significant attention. However, security will be an important factor for their full adoption. Wireless sensor nodes pose unique challenges and as such traditional security protocols, used in traditional networks cannot be applied directly. Some new protocols have been published recently with the goal of providing both privacy of data and authentication of sensor nodes for WSNs. Such protocols can employ private-key and/or public key cryptographic algorithms. Public key algorithms hold the promise of simplifying the network infrastructure required to provide security services such as: privacy, authentication and non-repudiation, while symmetric algorithms require less processing power on the lower power wireless node. In this paper a selection of key establishment/agreement protocols are reviewed and they are broadly divided into two categories: group key agreement protocols and pair-wise key establishment protocols. A summary of the capabilities and security related services provided by each protocol is provided.

Improvement of soluble coffee aroma using an integrated process of supercritical CO2 extraction with selective removal of the pungent volatiles by adsorption on activates carbon

Directory of Open Access Journals (Sweden)

S. Lucas

2006-06-01

Full Text Available In this paper a two-step integrated process consisting of CO2 supercritical extraction of volatile coffee compounds (the most valuable from roasted and milled coffee, and a subsequent step of selective removal of pungent volatiles by adsorption on activated carbon is presented. Some experiments were carried out with key compounds from roasted coffee aroma in order to study the adsorption step: ethyl acetate as a desirable compound and furfural as a pungent component. Operational parameters such as adsorption pressure and temperature and CO2 flowrate were optimized. Experiments were conducted at adsorption pressures of 12-17 MPa, adsorption temperatures of 35-50ºC and a solvent flow rate of 3-5 kg/h. In all cases, the solute concentration and the activated particle size were kept constant. Results show that low pressures (12 MPa, low temperatures (35ºC and low CO2 flowrates (3 kg/h are suitable for removing the undesirable pungent and smell components (e.g. furfural and retaining the desirable aroma compounds (e.g. ethyl acetate. The later operation with real roasted coffee has corroborated the previous results obtained with the key compounds.

Eurosites insights; image, implementation, interpretation and integration of Natura 2000 in European perspective; United Kingdom, Sweden, Spain, France and Hungary

NARCIS (Netherlands)

Neven, M.G.G.; Kistenkas, F.H.; Apeldoorn, van R.C.

2005-01-01

This comparative study analyses Natura 2000 nature conservation (EU Birds- and Habitats Directives) alongside the key issues of image, implementation, interpretation and integration. Having quickscanned the EU25, five member states have been selected for further investigation: UK, Sweden, Spain,

Delta's Key to the TOEFL iBT[R]: Advanced Skill Practice. Revised Edition

Science.gov (United States)

Gallagher, Nancy

2012-01-01

Delta's Key to the TOEFL iBT: Advanced Skill Practice is a revised and updated edition of Delta's Key to the Next Generation TOEFL Test. Since the introduction of the TOEFL iBT in 2005, there have been significant changes to some of the test questions, particularly the integrated writing and integrated speaking tasks. The new 2011 edition of…

SARS: Key factors in crisis management.

Science.gov (United States)

Tseng, Hsin-Chao; Chen, Thai-Form; Chou, Shieu-Ming

2005-03-01

This study was conducted at a single hospital selected in Taipei during the SARS (Severe Acute Respiratory Syndrome) outbreak from March to July, 2003 in Taiwan. During this period of time, 104 SARS patients were admitted to the hospital. There were no negative reports related to the selected hospital despite its being located right in the center of an area struck by the epidemic. The purpose of this study was to identify the key factors enabling the hospital to survive SARS unscathed. Data were collected from in-depth interviews with the nursing directors and nursing managers of the SARS units, along with a review of relevant hospital documents. The five key elements identified as survival factors during this SARS crisis are as follows: 1. good control of timing for crisis management, 2. careful decision-making, 3. thorough implementation, 4. effective communication, and 5. trust between management and employees. The results of this study reconfirmed the selected hospital as a model for good crisis management during the SARS epidemic.

Ranunculaceae of the Western Ukraine. І. Identification key

OpenAIRE

Novikoff A.

2013-01-01

In these paper the identification key for Ranunculaceae of Lviv, Transcarpathian (Zakarpattia), Rivne, Volhynia, Ivano-Frankivsk, Chernivtsi, Ternopil and Khmelnitsk regions (oblasts) is introduced. The key includes 102 species. It is based on contemporary investigations on taxonomy of the family Ranunculaceae. The key is carried out up to the level of species but in some cases there are short remarks about subspecific structure of selected taxa. Also it is supported by short notes about ...

Handbook of mathematical formulas and integrals

CERN Document Server

Jeffrey, Alan

2003-01-01

The updated Handbook is an essential reference for researchers and students in applied mathematics, engineering, and physics. It provides quick access to important formulas, relations, and methods from algebra, trigonometric and exponential functions, combinatorics, probability, matrix theory, calculus and vector calculus, ordinary and partial differential equations, Fourier series, orthogonal polynomials, and Laplace transforms. Many of the entries are based upon the updated sixth edition of Gradshteyn and Ryzhik''s Table of Integrals, Series, and Products and other important reference works.The Third Edition has new chapters covering solutions of elliptic, parabolic and hyperbolic equations and qualitative properties of the heat and Laplace equation.Key Features: * Comprehensive coverage of frequently used integrals, functions and fundamental mathematical results * Contents selected and organized to suit the needs of students, scientists, and engineers * Contains tables of Laplace and Fourier transfor...

Key Aspects of Nucleic Acid Library Design for in Vitro Selection

Science.gov (United States)

Vorobyeva, Maria A.; Davydova, Anna S.; Vorobjev, Pavel E.; Pyshnyi, Dmitrii V.; Venyaminova, Alya G.

2018-01-01

Nucleic acid aptamers capable of selectively recognizing their target molecules have nowadays been established as powerful and tunable tools for biospecific applications, be it therapeutics, drug delivery systems or biosensors. It is now generally acknowledged that in vitro selection enables one to generate aptamers to almost any target of interest. However, the success of selection and the affinity of the resulting aptamers depend to a large extent on the nature and design of an initial random nucleic acid library. In this review, we summarize and discuss the most important features of the design of nucleic acid libraries for in vitro selection such as the nature of the library (DNA, RNA or modified nucleotides), the length of a randomized region and the presence of fixed sequences. We also compare and contrast different randomization strategies and consider computer methods of library design and some other aspects. PMID:29401748

Integration of laser trapping for continuous and selective monitoring of photothermal response of a single microparticle.

Science.gov (United States)

Vasudevan, Srivathsan; Chen, George C K; Ahluwalia, Balpreet Singh

2008-12-01

Photothermal response (PTR) is an established pump and probe technique for real-time sensing of biological assays. Continuous and selective PTR monitoring is difficult owing to the Brownian motion changing the relative position of the target with respect to the beams. Integration of laser trapping with PTR is proposed as a solution. The proposed method is verified on red polystyrene microparticles. PTR is continuously monitored for 30 min. Results show that the mean relaxation time variation of the acquired signals is less than 5%. The proposed method is then applied to human red blood cells for continuous and selective PTR.

Accuracy and responses of genomic selection on key traits in apple breeding

NARCIS (Netherlands)

Muranty, Hélène; Troggio, Michela; Sadok, Ben Inès; Rifaï, Al Mehdi; Auwerkerken, Annemarie; Banchi, E.; Velasco, Riccardo; Stevanato, P.; Weg, van de W.E.; Guardo, Di M.; Kumar, S.; Laurens, François; Bink, M.C.A.M.

2015-01-01

The application of genomic selection in fruit tree crops is expected to enhance breeding efficiency by increasing prediction accuracy, increasing selection intensity and decreasing generation interval. The objectives of this study were to assess the accuracy of prediction and selection response in

Coherent one-way quantum key distribution

Science.gov (United States)

Stucki, Damien; Fasel, Sylvain; Gisin, Nicolas; Thoma, Yann; Zbinden, Hugo

2007-05-01

Quantum Key Distribution (QKD) consists in the exchange of a secrete key between two distant points [1]. Even if quantum key distribution systems exist and commercial systems are reaching the market [2], there are still improvements to be made: simplify the construction of the system; increase the secret key rate. To this end, we present a new protocol for QKD tailored to work with weak coherent pulses and at high bit rates [3]. The advantages of this system are that the setup is experimentally simple and it is tolerant to reduced interference visibility and to photon number splitting attacks, thus resulting in a high efficiency in terms of distilled secret bits per qubit. After having successfully tested the feasibility of the system [3], we are currently developing a fully integrated and automated prototype within the SECOQC project [4]. We present the latest results using the prototype. We also discuss the issue of the photon detection, which still remains the bottleneck for QKD.

Operational plans for life science payloads - From experiment selection through postflight reporting

Science.gov (United States)

Mccollum, G. W.; Nelson, W. G.; Wells, G. W.

1976-01-01

Key features of operational plans developed in a study of the Space Shuttle era life science payloads program are presented. The data describes the overall acquisition, staging, and integration of payload elements, as well as program implementation methods and mission support requirements. Five configurations were selected as representative payloads: (a) carry-on laboratories - medical emphasis experiments, (b) mini-laboratories - medical/biology experiments, (c) seven-day dedicated laboratories - medical/biology experiments, (d) 30-day dedicated laboratories - Regenerative Life Support Evaluation (RLSE) with selected life science experiments, and (e) Biomedical Experiments Scientific Satellite (BESS) - extended duration primate (Type I) and small vertebrate (Type II) missions. The recommended operational methods described in the paper are compared to the fundamental data which has been developed in the life science Spacelab Mission Simulation (SMS) test series. Areas assessed include crew training, experiment development and integration, testing, data-dissemination, organization interfaces, and principal investigator working relationships.

National disease management plans for key chronic non-communicable diseases in Singapore.

Science.gov (United States)

Tan, C C

2002-07-01

In Singapore, chronic, non-communicable diseases, namely coronary heart disease, stroke and cancer, account for more than 60% of all deaths and a high burden of disability and healthcare expenditure. The burden of these diseases is likely to rise with our rapidly ageing population and changing lifestyles, and will present profound challenges to our healthcare delivery and financing systems over the next 20 to 30 years. The containment and optimal management of these conditions require a strong emphasis on patient education and the development of integrated models of healthcare delivery in place of the present uncoordinated, compartmentalised way of delivering healthcare. To meet these challenges, the Ministry of Health's major thrusts are disease control measures which focus mainly on primary prevention; and disease management, which coordinates the national effort to reduce the incidence of these key diseases and their predisposing factors and to ameliorate their long-term impact by optimising control to reduce mortality, morbidity and complications, and improving functional status through rehabilitation. The key initiatives include restructuring of the public sector healthcare institutions into two clusters, each comprising a network of primary health care polyclinics, regional hospitals and tertiary institutions. The functional integration of these healthcare elements within each cluster under a common senior administrative and professional management, and the development of common clinical IT systems will greatly facilitate the implementation of disease management programmes. Secondly, the Ministry is establishing National Disease Registries in coronary heart disease, cancer, stroke, myopia and kidney failure, which will be valuable sources of clinical and outcomes data. Thirdly, in partnership with expert groups, national committees and professional agencies, the Ministry will produce clinical practice guidelines which will assist doctors and healthcare

Organizational Context and Capabilities for Integrating Care: A Framework for Improvement

Directory of Open Access Journals (Sweden)

Jenna M. Evans

2016-08-01

Full Text Available Background: Interventions aimed at integrating care have become widespread in healthcare; however, there is significant variability in their success. Differences in organizational contexts and associated capabilities may be responsible for some of this variability. Purpose: This study develops and validates a conceptual framework of organizational capabilities for integrating care, identifies which of these capabilities may be most important, and explores the mechanisms by which they influence integrated care efforts.  Methods: The Context and Capabilities for Integrating Care (CCIC Framework was developed through a literature review, and revised and validated through interviews with leaders and care providers engaged in integrated care networks in Ontario, Canada. Interviews involved open-ended questions and graphic elicitation. Quantitative content analysis was used to summarize the data.  Results: The CCIC Framework consists of eighteen organizational factors in three categories: Basic Structures, People and Values, and Key Processes. The three most important capabilities shaping the capacity of organizations to implement integrated care interventions include Leadership Approach, Clinician Engagement and Leadership, and Readiness for Change. The majority of hypothesized relationships among organizational capabilities involved Readiness for Change and Partnering, emphasizing the complexity, interrelatedness and importance of these two factors to integrated care efforts.  Conclusions: Organizational leaders can use the framework to determine readiness to integrate care, develop targeted change management strategies, and select appropriate partners with overlapping or complementary profiles on key capabilities. Researchers may use the results to test and refine the proposed framework, with a focus on the hypothesized relationships among organizational capabilities and between organizational capabilities and performance outcomes.

Organizational Context and Capabilities for Integrating Care: A Framework for Improvement

Science.gov (United States)

Grudniewicz, Agnes; Baker, G. Ross; Wodchis, Walter P.

2016-01-01

Background: Interventions aimed at integrating care have become widespread in healthcare; however, there is significant variability in their success. Differences in organizational contexts and associated capabilities may be responsible for some of this variability. Purpose: This study develops and validates a conceptual framework of organizational capabilities for integrating care, identifies which of these capabilities may be most important, and explores the mechanisms by which they influence integrated care efforts. Methods: The Context and Capabilities for Integrating Care (CCIC) Framework was developed through a literature review, and revised and validated through interviews with leaders and care providers engaged in integrated care networks in Ontario, Canada. Interviews involved open-ended questions and graphic elicitation. Quantitative content analysis was used to summarize the data. Results: The CCIC Framework consists of eighteen organizational factors in three categories: Basic Structures, People and Values, and Key Processes. The three most important capabilities shaping the capacity of organizations to implement integrated care interventions include Leadership Approach, Clinician Engagement and Leadership, and Readiness for Change. The majority of hypothesized relationships among organizational capabilities involved Readiness for Change and Partnering, emphasizing the complexity, interrelatedness and importance of these two factors to integrated care efforts. Conclusions: Organizational leaders can use the framework to determine readiness to integrate care, develop targeted change management strategies, and select appropriate partners with overlapping or complementary profiles on key capabilities. Researchers may use the results to test and refine the proposed framework, with a focus on the hypothesized relationships among organizational capabilities and between organizational capabilities and performance outcomes. PMID:28413366

Collaboration: The key to integration of language and content in ...

African Journals Online (AJOL)

This contribution enters into dialogue with studies conducted both at school and university level on the effectiveness of interaction between subject teachers and language teachers to improve learners' subject-specific discourse literacies. An overview is given of the key findings of a report by the National Center for Literacy ...

The selection of a mode of urban transportation: Integrating psychological variables to discrete choice models

International Nuclear Information System (INIS)

Cordoba Maquilon, Jorge E; Gonzalez Calderon, Carlos A; Posada Henao, John J

2011-01-01

A study using revealed preference surveys and psychological tests was conducted. Key psychological variables of behavior involved in the choice of transportation mode in a population sample of the Metropolitan Area of the Valle de Aburra were detected. The experiment used the random utility theory for discrete choice models and reasoned action in order to assess beliefs. This was used as a tool for analysis of the psychological variables using the sixteen personality factor questionnaire (16PF test). In addition to the revealed preference surveys, two other surveys were carried out: one with socio-economic characteristics and the other with latent indicators. This methodology allows for an integration of discrete choice models and latent variables. The integration makes the model operational and quantifies the unobservable psychological variables. The most relevant result obtained was that anxiety affects the choice of urban transportation mode and shows that physiological alterations, as well as problems in perception and beliefs, can affect the decision-making process.

Key-value Storage Systems (and Beyond with Python

Directory of Open Access Journals (Sweden)

2010-09-01

Full Text Available Web application developers often use RDBMS systems such as MySql or PostgreSql but there are many other types of databases out there. Key-value storage, schema and schema-less document storage, and column-oriented DBMS systems abound. These kind of database systems are becoming more popular when developing scalable web applications but many developers are unsure how to integrate them into their projects. This talk will focus on the key-value class of data storage systems, weigh the strengths and drawbacks of each and discuss typical use cases for key value storage.

Sensor Selection and Data Validation for Reliable Integrated System Health Management

Science.gov (United States)

Garg, Sanjay; Melcher, Kevin J.

2008-01-01

For new access to space systems with challenging mission requirements, effective implementation of integrated system health management (ISHM) must be available early in the program to support the design of systems that are safe, reliable, highly autonomous. Early ISHM availability is also needed to promote design for affordable operations; increased knowledge of functional health provided by ISHM supports construction of more efficient operations infrastructure. Lack of early ISHM inclusion in the system design process could result in retrofitting health management systems to augment and expand operational and safety requirements; thereby increasing program cost and risk due to increased instrumentation and computational complexity. Having the right sensors generating the required data to perform condition assessment, such as fault detection and isolation, with a high degree of confidence is critical to reliable operation of ISHM. Also, the data being generated by the sensors needs to be qualified to ensure that the assessments made by the ISHM is not based on faulty data. NASA Glenn Research Center has been developing technologies for sensor selection and data validation as part of the FDDR (Fault Detection, Diagnosis, and Response) element of the Upper Stage project of the Ares 1 launch vehicle development. This presentation will provide an overview of the GRC approach to sensor selection and data quality validation and will present recent results from applications that are representative of the complexity of propulsion systems for access to space vehicles. A brief overview of the sensor selection and data quality validation approaches is provided below. The NASA GRC developed Systematic Sensor Selection Strategy (S4) is a model-based procedure for systematically and quantitatively selecting an optimal sensor suite to provide overall health assessment of a host system. S4 can be logically partitioned into three major subdivisions: the knowledge base, the down-select

Observing with a space-borne gamma-ray telescope: selected results from INTEGRAL

International Nuclear Information System (INIS)

Schanne, Stephane

2006-01-01

The International Gamma-Ray Astrophysics Laboratory, i.e. the INTEGRAL satellite of ESA, in orbit since about 3 years, performs gamma-ray observations of the sky in the 15 keV to 8 MeV energy range. Thanks to its imager IBIS, and in particular the ISGRI detection plane based on 16384 CdTe pixels, it achieves an excellent angular resolution (12 arcmin) for point source studies with good continuum spectrum sensitivity. Thanks to its spectrometer SPI, based on 19 germanium detectors maintained at 85 K by a cryogenic system, located inside an active BGO veto shield, it achieves excellent spectral resolution of about 2 keV for 1 MeV photons, which permits astrophysical gamma-ray line studies with good narrow-line sensitivity. In this paper we review some goals of gamma-ray astronomy from space and present the INTEGRAL satellite, in particular its instruments ISGRI and SPI. Ground and in-flight calibration results from SPI are presented, before presenting some selected astrophysical results from INTEGRAL. In particular results on point source searches are presented, followed by results on nuclear astrophysics, exemplified by the study of the 1809 keV gamma-ray line from radioactive 26 Al nuclei produced by the ongoing stellar nucleosynthesis in the Galaxy. Finally a review on the study of the positron-electron annihilation in the Galactic center region, producing 511 keV gamma-rays, is presented

Integrated care: wellness-oriented peer approaches: a key ingredient for integrated care.

Science.gov (United States)

Swarbrick, Margaret A

2013-08-01

People with lived experience of mental illness have become leaders of an influential movement to help the mental health system embrace the notion of whole health and wellness in the areas of advocacy, policy, and care delivery. Wellness-oriented peer approaches delivered by peer-support whole-health specialists and wellness coaches can play an important role in integrated care models. This column examines the wellness definitions and peer models and some specific benefits and tensions between the peer-oriented wellness approach and the medical model. These models can work in unison to improve health and wellness among people with mental and substance use disorders.

Low-Power Public Key Cryptography

Energy Technology Data Exchange (ETDEWEB)

BEAVER,CHERYL L.; DRAELOS,TIMOTHY J.; HAMILTON,VICTORIA A.; SCHROEPPEL,RICHARD C.; GONZALES,RITA A.; MILLER,RUSSELL D.; THOMAS,EDWARD V.

2000-11-01

This report presents research on public key, digital signature algorithms for cryptographic authentication in low-powered, low-computation environments. We assessed algorithms for suitability based on their signature size, and computation and storage requirements. We evaluated a variety of general purpose and special purpose computing platforms to address issues such as memory, voltage requirements, and special functionality for low-powered applications. In addition, we examined custom design platforms. We found that a custom design offers the most flexibility and can be optimized for specific algorithms. Furthermore, the entire platform can exist on a single Application Specific Integrated Circuit (ASIC) or can be integrated with commercially available components to produce the desired computing platform.

The Quality of Governance and EU Regional Policy as a key determinant in the process of the integration of the Western Balkans into the EU

Directory of Open Access Journals (Sweden)

Demush Bajrami

2017-12-01

Full Text Available This paper analyzes the quality of governance and financial assistance as key determinants for successful functioning of the process of integration within the European Union (EU. Moreover, the paper develops a comparison of the Western Balkans with current EU members and the forthcoming, on the basis of the selected indicators of governance (rule of law, democracy, corruption, political stability, and effectiveness of state with the experience of the implementation of the reforms of public administration. Various surveys show that the Western Balkans, by all quality of governance indicators, especially in the rule of law, lags behind 28 (twenty eight of the current EU countries (without taking in account the Great Britain. The low level of the functioning of rule of law, combined with inadequate and unreformed public administration is potentially the biggest obstacle in the association agreement of the Western Balkans with EU, but also as challenge in achieving sustainable social and economic development. Whereas in the case of the Western Balkan countries, there is an obvious difference between proclaiming and internal reality, which is further compounded by a difficult political and economic transition, as well as in social domain - where poverty and corruption are the most worrying. The research data obtained from independent bodies - academic and research institutions, civil society and international organizations - confirm this controversial picture of the Western Balkans. Negative attitudes still prevail in Western Balkans political elites and if given the chance to political manipulation, may behave unpredictably. All this makes it obligatory to make a comparative overview, for depicting in particular the quality of governance as sine qua non for the Western Balkans countries‘ integration in EU.

Selection of key terrain attributes for SOC model

DEFF Research Database (Denmark)

Greve, Mogens Humlekrog; Adhikari, Kabindra; Chellasamy, Menaka

As an important component of the global carbon pool, soil organic carbon (SOC) plays an important role in the global carbon cycle. SOC pool is the basic information to carry out global warming research, and needs to sustainable use of land resources. Digital terrain attributes are often use...... was selected, total 2,514,820 data mining models were constructed by 71 differences grid from 12m to 2304m and 22 attributes, 21 attributes derived by DTM and the original elevation. Relative importance and usage of each attributes in every model were calculated. Comprehensive impact rates of each attribute...

Improved two-way six-state protocol for quantum key distribution

International Nuclear Information System (INIS)

Shaari, J.S.; Bahari, Asma' Ahmad

2012-01-01

A generalized version for a qubit based two-way quantum key distribution scheme was first proposed in the paper [Phys. Lett. A 358 (2006) 85] capitalizing on the six quantum states derived from three mutually unbiased bases. While boasting of a higher level of security, the protocol was not designed for ease of practical implementation. In this work, we propose modifications to the protocol, resulting not only in improved security but also in a more efficient and practical setup. We provide comparisons for calculated secure key rates for the protocols in noisy and lossy channels. -- Highlights: ► Modification for efficient generalized two-way QKD is proposed. ► Calculations include secure key rates in noisy and lossy channels for selected attack scenario. ► Resulting proposal provides for higher secure key rate in selected attack scheme.

Improved two-way six-state protocol for quantum key distribution

Energy Technology Data Exchange (ETDEWEB)

Shaari, J.S., E-mail: jesni_shamsul@yahoo.com [Faculty of Science, International Islamic University Malaysia (IIUM), Jalan Sultan Ahmad Shah, Bandar Indera Mahkota, 25200 Kuantan, Pahang (Malaysia); Bahari, Asma' Ahmad [Faculty of Science, International Islamic University Malaysia (IIUM), Jalan Sultan Ahmad Shah, Bandar Indera Mahkota, 25200 Kuantan, Pahang (Malaysia)

2012-10-01

A generalized version for a qubit based two-way quantum key distribution scheme was first proposed in the paper [Phys. Lett. A 358 (2006) 85] capitalizing on the six quantum states derived from three mutually unbiased bases. While boasting of a higher level of security, the protocol was not designed for ease of practical implementation. In this work, we propose modifications to the protocol, resulting not only in improved security but also in a more efficient and practical setup. We provide comparisons for calculated secure key rates for the protocols in noisy and lossy channels. -- Highlights: ► Modification for efficient generalized two-way QKD is proposed. ► Calculations include secure key rates in noisy and lossy channels for selected attack scenario. ► Resulting proposal provides for higher secure key rate in selected attack scheme.

Toward integration of genomic selection with crop modelling: the development of an integrated approach to predicting rice heading dates.

Science.gov (United States)

Onogi, Akio; Watanabe, Maya; Mochizuki, Toshihiro; Hayashi, Takeshi; Nakagawa, Hiroshi; Hasegawa, Toshihiro; Iwata, Hiroyoshi

2016-04-01

It is suggested that accuracy in predicting plant phenotypes can be improved by integrating genomic prediction with crop modelling in a single hierarchical model. Accurate prediction of phenotypes is important for plant breeding and management. Although genomic prediction/selection aims to predict phenotypes on the basis of whole-genome marker information, it is often difficult to predict phenotypes of complex traits in diverse environments, because plant phenotypes are often influenced by genotype-environment interaction. A possible remedy is to integrate genomic prediction with crop/ecophysiological modelling, which enables us to predict plant phenotypes using environmental and management information. To this end, in the present study, we developed a novel method for integrating genomic prediction with phenological modelling of Asian rice (Oryza sativa, L.), allowing the heading date of untested genotypes in untested environments to be predicted. The method simultaneously infers the phenological model parameters and whole-genome marker effects on the parameters in a Bayesian framework. By cultivating backcross inbred lines of Koshihikari × Kasalath in nine environments, we evaluated the potential of the proposed method in comparison with conventional genomic prediction, phenological modelling, and two-step methods that applied genomic prediction to phenological model parameters inferred from Nelder-Mead or Markov chain Monte Carlo algorithms. In predicting heading dates of untested lines in untested environments, the proposed and two-step methods tended to provide more accurate predictions than the conventional genomic prediction methods, particularly in environments where phenotypes from environments similar to the target environment were unavailable for training genomic prediction. The proposed method showed greater accuracy in prediction than the two-step methods in all cross-validation schemes tested, suggesting the potential of the integrated approach in

Object-based attention benefits reveal selective abnormalities of visual integration in autism.

Science.gov (United States)

Falter, Christine M; Grant, Kate C Plaisted; Davis, Greg

2010-06-01

A pervasive integration deficit could provide a powerful and elegant account of cognitive processing in autism spectrum disorders (ASD). However, in the case of visual Gestalt grouping, typically assessed by tasks that require participants explicitly to introspect on their own grouping perception, clear evidence for such a deficit remains elusive. To resolve this issue, we adopt an index of Gestalt grouping from the object-based attention literature that does not require participants to assess their own grouping perception. Children with ASD and mental- and chronological-age matched typically developing children (TD) performed speeded orientation discriminations of two diagonal lines. The lines were superimposed on circles that were either grouped together or segmented on the basis of color, proximity or these two dimensions in competition. The magnitude of performance benefits evident for grouped circles, relative to ungrouped circles, provided an index of grouping under various conditions. Children with ASD showed comparable grouping by proximity to the TD group, but reduced grouping by similarity. ASD seems characterized by a selective bias away from grouping by similarity combined with typical levels of grouping by proximity, rather than by a pervasive integration deficit.

Ranunculaceae of the Western Ukraine. І. Identification key

Directory of Open Access Journals (Sweden)

Andrew V. Novikoff

2013-04-01

Full Text Available In these paper the identification key for Ranunculaceae of Lviv, Transcarpathian (Zakarpattia, Rivne, Volhynia, Ivano-Frankivsk, Chernivtsi, Ternopil and Khmelnitsk regions (oblasts is introduced. The key includes 102 species. It is based on contemporary investigations on taxonomy of the family Ranunculaceae. The key is carried out up to the level of species but in some cases there are short remarks about subspecific structure of selected taxa. Also it is supported by short notes about distribution, ornamental usage and protection of represented species.

Machine Selection in A Dairy Product Company with Entropy and SAW Method Integration

Directory of Open Access Journals (Sweden)

Aşkın Özdağoğlu

2017-07-01

Full Text Available Machine selection is an important and difficult process for the firms, and its results may generate more problems than anticipated. In order to find the best alternative, managers should define the requirements of the factory and determine the necessary criteria. On the other hand, the decision making criteria in order to choose the right equipment may vary according to the type of the manufacturing facility, market requirements, and consumer assigned criteria. This study aims to find the best machine alternative  among  the three machine offerings according to twelve evaluation criteria by integrating entropy method with SAW method.

Highlights Eurosites insights; highlights on image, implementation, interpretation and integration of Natura 2000 in European perspective; United Kingdom, Sweden, Spain, France and Hungary

NARCIS (Netherlands)

Neven, M.G.G.; Kistenkas, F.H.

2005-01-01

Highlighting the main report Eurosites Insights this comparative study analyses Natura 2000 nature conservation (EU Birds- and Habitats Directives) alongside the key issues of image, implementation, interpretation and integration. Having quick scanned the EU25, five member states have been selected

Programmable optical processor chips: toward photonic RF filters with DSP-level flexibility and MHz-band selectivity

Directory of Open Access Journals (Sweden)

Xie Yiwei

2017-12-01

Full Text Available Integrated optical signal processors have been identified as a powerful engine for optical processing of microwave signals. They enable wideband and stable signal processing operations on miniaturized chips with ultimate control precision. As a promising application, such processors enables photonic implementations of reconfigurable radio frequency (RF filters with wide design flexibility, large bandwidth, and high-frequency selectivity. This is a key technology for photonic-assisted RF front ends that opens a path to overcoming the bandwidth limitation of current digital electronics. Here, the recent progress of integrated optical signal processors for implementing such RF filters is reviewed. We highlight the use of a low-loss, high-index-contrast stoichiometric silicon nitride waveguide which promises to serve as a practical material platform for realizing high-performance optical signal processors and points toward photonic RF filters with digital signal processing (DSP-level flexibility, hundreds-GHz bandwidth, MHz-band frequency selectivity, and full system integration on a chip scale.

Hybrid integrated single-wavelength laser with silicon micro-ring reflector

Science.gov (United States)

Ren, Min; Pu, Jing; Krishnamurthy, Vivek; Xu, Zhengji; Lee, Chee-Wei; Li, Dongdong; Gonzaga, Leonard; Toh, Yeow T.; Tjiptoharsono, Febi; Wang, Qian

2018-02-01

A hybrid integrated single-wavelength laser with silicon micro-ring reflector is demonstrated theoretically and experimentally. It consists of a heterogeneously integrated III-V section for optical gain, an adiabatic taper for light coupling, and a silicon micro-ring reflector for both wavelength selection and light reflection. Heterogeneous integration processes for multiple III-V chips bonded to an 8-inch Si wafer have been developed, which is promising for massive production of hybrid lasers on Si. The III-V layer is introduced on top of a 220-nm thick SOI layer through low-temperature wafer-boning technology. The optical coupling efficiency of >85% between III-V and Si waveguide has been achieved. The silicon micro-ring reflector, as the key element of the hybrid laser, is studied, with its maximized reflectivity of 85.6% demonstrated experimentally. The compact single-wavelength laser enables fully monolithic integration on silicon wafer for optical communication and optical sensing application.

KEY CONCEPTS OF AGROECOLOGY SCIENCE. A SYSTEMATIC REVIEW

Directory of Open Access Journals (Sweden)

Luis Fernando Gómez-Echeverri

2016-08-01

Full Text Available A systematic review was conducted with the objective of determining the key concepts that are currently used in theoretical work in agroecology. They were obtained from titles and keywords of theoretical articles and books that included the term agroecology in the title. Fifteen terms with occurrences higher than three were obtained. They show that agroecology revolves around the concept of integral sustainability, and that there is agreement on neither its object of study nor goal. As a result, most key concepts concern the object of study or the goal of agroecology. Other key concepts are food sovereignty, agriculture, ecofeminism, climate change, family farming, and social movements.

Integrating economic parameters into genetic selection for Large White pigs.

Science.gov (United States)

Dube, Bekezela; Mulugeta, Sendros D; Dzama, Kennedy

2013-08-01

The objective of the study was to integrate economic parameters into genetic selection for sow productivity, growth performance and carcass characteristics in South African Large White pigs. Simulation models for sow productivity and terminal production systems were performed based on a hypothetical 100-sow herd, to derive economic values for the economically relevant traits. The traits included in the study were number born alive (NBA), 21-day litter size (D21LS), 21-day litter weight (D21LWT), average daily gain (ADG), feed conversion ratio (FCR), age at slaughter (AGES), dressing percentage (DRESS), lean content (LEAN) and backfat thickness (BFAT). Growth of a pig was described by the Gompertz growth function, while feed intake was derived from the nutrient requirements of pigs at the respective ages. Partial budgeting and partial differentiation of the profit function were used to derive economic values, which were defined as the change in profit per unit genetic change in a given trait. The respective economic values (ZAR) were: 61.26, 38.02, 210.15, 33.34, -21.81, -68.18, 5.78, 4.69 and -1.48. These economic values indicated the direction and emphases of selection, and were sensitive to changes in feed prices and marketing prices for carcasses and maiden gilts. Economic values for NBA, D21LS, DRESS and LEAN decreased with increasing feed prices, suggesting a point where genetic improvement would be a loss, if feed prices continued to increase. The economic values for DRESS and LEAN increased as the marketing prices for carcasses increased, while the economic value for BFAT was not sensitive to changes in all prices. Reductions in economic values can be counterbalanced by simultaneous increases in marketing prices of carcasses and maiden gilts. Economic values facilitate genetic improvement by translating it to proportionate profitability. Breeders should, however, continually recalculate economic values to place the most appropriate emphases on the respective

A Conceptual Characterization of Online Videos Explaining Natural Selection

Science.gov (United States)

Bohlin, Gustav; Göransson, Andreas; Höst, Gunnar E.; Tibell, Lena A. E.

2017-11-01

Educational videos on the Internet comprise a vast and highly diverse source of information. Online search engines facilitate access to numerous videos claiming to explain natural selection, but little is known about the degree to which the video content match key evolutionary content identified as important in evolution education research. In this study, we therefore analyzed the content of 60 videos accessed through the Internet, using a criteria catalog with 38 operationalized variables derived from research literature. The variables were sorted into four categories: (a) key concepts (e.g. limited resources and inherited variation), (b) threshold concepts (abstract concepts with a transforming and integrative function), (c) misconceptions (e.g. that evolution is driven by need), and (d) organismal context (e.g. animal or plant). The results indicate that some concepts are frequently communicated, and certain taxa are commonly used to illustrate concepts, while others are seldom included. In addition, evolutionary phenomena at small temporal and spatial scales, such as subcellular processes, are rarely covered. Rather, the focus is on population-level events over time scales spanning years or longer. This is consistent with an observed lack of explanations regarding how randomly occurring mutations provide the basis for variation (and thus natural selection). The findings imply, among other things, that some components of natural selection warrant far more attention in biology teaching and science education research.

Playing with Gladys: A case study integrating drama therapy with behavioural interventions for the treatment of selective mutism.

Science.gov (United States)

Oon, Phei Phei

2010-04-01

This case study examines an integrative approach combining drama therapy and the behavioural skill "shaping", as offered to Gladys, a 5-year-old girl diagnosed with selective mutism. This study found that shaping, when implemented in the context of play, with play as the primary reinforcer, elicited from Gladys vocalization and eventually speech within a very short time. Her vocalizations allowed her to enter dramatic play, which in turn propelled spontaneous speech. This article looks at how the three elements of dramatherapy - the playspace, role-playing and dramatic projection - brought about therapeutic changes for Gladys. Aside from spontaneous speech, Gladys also developed positive self-esteem and a heightened sense of spontaneity. Subsequently, these two qualities helped her generalize her speech to new settings on her own. Gladys's newly harnessed spontaneity further helped her become more sociable and resilient.This study advances the possibility of integrating a behavioural skill with drama therapy for the therapeutic benefits of a child with an anxiety-related condition like selective mutism.

Harmonising and semantically linking key variables from in-situ observing networks of an Integrated Atlantic Ocean Observing System, AtlantOS

Science.gov (United States)

Darroch, Louise; Buck, Justin

2017-04-01

Atlantic Ocean observation is currently undertaken through loosely-coordinated, in-situ observing networks, satellite observations and data management arrangements at regional, national and international scales. The EU Horizon 2020 AtlantOS project aims to deliver an advanced framework for the development of an Integrated Atlantic Ocean Observing System that strengthens the Global Ocean Observing System (GOOS) and contributes to the aims of the Galway Statement on Atlantic Ocean Cooperation. One goal is to ensure that data from different and diverse in-situ observing networks are readily accessible and useable to a wider community, including the international ocean science community and other stakeholders in this field. To help achieve this goal, the British Oceanographic Data Centre (BODC) produced a parameter matrix to harmonise data exchange, data flow and data integration for the key variables acquired by multiple in-situ AtlantOS observing networks such as ARGO, Seafloor Mapping and OceanSITES. Our solution used semantic linking of controlled vocabularies and metadata for parameters that were "mappable" to existing EU and international standard vocabularies. An AtlantOS Essential Variables list of terms (aggregated level) based on Global Climate Observing System (GCOS) Essential Climate Variables (ECV), GOOS Essential Ocean Variables (EOV) and other key network variables was defined and published on the Natural Environment Research Council (NERC) Vocabulary Server (version 2.0) as collection A05 (http://vocab.nerc.ac.uk/collection/A05/current/). This new vocabulary was semantically linked to standardised metadata for observed properties and units that had been validated by the AtlantOS community: SeaDataNet parameters (P01), Climate and Forecast (CF) Standard Names (P07) and SeaDataNet units (P06). Observed properties were mapped to biological entities from the internationally assured AphiaID from the WOrld Register of Marine Species (WoRMS), http

An integrated dataset on organisational retention attributes and commitment of selected ICT and accounting firms

Directory of Open Access Journals (Sweden)

Odunayo Salau

2018-06-01

Full Text Available The article presented an integrated data on organisational retention strategies and commitment of selected ICT and Accounting firms in Nigeria. The study adopted a quantitative approach with a survey research design to establish the major determinants of employee retention strategies. The population of this study included staff and management of the selected firms. Data was analysed with the use of structural equation modelling and the field data set is made widely accessible to enable critical or a more comprehensive investigation. The findings identified critical attraction factors for the retention of sampled firms. It was recommended that ICT firms will need to adopt consistent range of strategies to attract and retain people with the right ICT skills, in the right place and at the right time. Keywords: Retention, Commitment, Reward, Satisfaction, Performance

Investigation of selected surface integrity features of duplex stainless steel (DSS after turning

Directory of Open Access Journals (Sweden)

G. Krolczyk

2015-01-01

Full Text Available The article presents surface roughness profiles and Abbott - Firestone curves with vertical and amplitude parameters of surface roughness after turning by means of a coated sintered carbide wedge with a coating with ceramic intermediate layer. The investigation comprised the influence of cutting speed on the selected features of surface integrity in dry machining. The material under investigation was duplex stainless steel with two-phase ferritic-austenitic structure. The tests have been performed under production conditions during machining of parts for electric motors and deep-well pumps. The obtained results allow to draw conclusions about the characteristics of surface properties of the machined parts.

Role of Smart Grids in Integrating Renewable Energy

Energy Technology Data Exchange (ETDEWEB)

Speer, B. [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Miller, M. [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Schaffer, W. [Salzburg AG (Austria); Gueran, L. [Fichtner IT Consulting AG, Stutgartt (Germany); Reuter, A. [Fichtner IT Consulting AG, Stutgartt (Germany); Jang, B. [Korea Smart Grid Inst., Seoul (Korea); Widegren, K. [Swedish Energy Markets Inspectorate, Eskilstuna (Sweden)

2015-05-27

This report was prepared for the International Smart Grid Action Network (ISGAN), which periodically publishes briefs and discussion papers on key topics of smart grid development globally. The topic of this report was selected by a multilateral group of national experts participating in ISGAN Annex 4, a working group that aims to produce synthesis insights for decision makers. This report is an update of a 2012 ISGAN Annex 4 report entitled “Smart Grid Contributions to Variable Renewable Resource Integration.” That report and other past publications of ISGAN Annexes can be found at www.iea-isgan.org and at www.cleanenergysolutions.org.

Information and image integration: project spectrum

Science.gov (United States)

Blaine, G. James; Jost, R. Gilbert; Martin, Lori; Weiss, David A.; Lehmann, Ron; Fritz, Kevin

1998-07-01

The BJC Health System (BJC) and the Washington University School of Medicine (WUSM) formed a technology alliance with industry collaborators to develop and implement an integrated, advanced clinical information system. The industry collaborators include IBM, Kodak, SBC and Motorola. The activity, called Project Spectrum, provides an integrated clinical repository for the multiple hospital facilities of the BJC. The BJC System consists of 12 acute care hospitals serving over one million patients in Missouri and Illinois. An interface engine manages transactions from each of the hospital information systems, lab systems and radiology information systems. Data is normalized to provide a consistent view for the primary care physician. Access to the clinical repository is supported by web-based server/browser technology which delivers patient data to the physician's desktop. An HL7 based messaging system coordinates the acquisition and management of radiological image data and sends image keys to the clinical data repository. Access to the clinical chart browser currently provides radiology reports, laboratory data, vital signs and transcribed medical reports. A chart metaphor provides tabs for the selection of the clinical record for review. Activation of the radiology tab facilitates a standardized view of radiology reports and provides an icon used to initiate retrieval of available radiology images. The selection of the image icon spawns an image browser plug-in and utilizes the image key from the clinical repository to access the image server for the requested image data. The Spectrum system is collecting clinical data from five hospital systems and imaging data from two hospitals. Domain specific radiology imaging systems support the acquisition and primary interpretation of radiology exams. The spectrum clinical workstations are deployed to over 200 sites utilizing local area networks and ISDN connectivity.

Integrated services as the key to the optimisation of refueling outages

International Nuclear Information System (INIS)

Ortega, Juan; Gonzalez, Roberto; Gutierrez, Jose E.

2010-01-01

Refueling outages at nuclear power plants are subject to demanding improvement criteria in each and every one of the activities scheduled. The management of activities on the refueling floor, including the phases of opening and closing of the reactor vessel and associated tasks relating to the reactor internals, the unloading, loading and management of the irradiated fuel and activities requested for the in-service inspection of essential primary circuit components, are interventions that have an impact on the refueling critical path and whose overall integration allows for significant optimization of the entire management of this fundamental refueling activity. For several years now, ENUSA, as the company specializing in irradiated fuel services, TECNATOM as the company responsible for the in-service inspection of critical primary side components and Westinghouse as the technology provider and specialist in the supply of plant support services, have together formed a solid working team offering this integrated refueling service to the Spanish plants. Today, the new and heightened demands regarding the training and specialization of the personnel participating in refueling outages, the need to consider contingencies in the activities scheduled and the objectives relating to the ALARA concept and safe operations require that this service include new activities providing synergies and leading to higher levels of commitment to excellence. This paper will present the service model developed, the most significant activities integrated in the service and the advantages and milestones achieved and reached during this period, compared to the conventional distributed functions model. Likewise, an analysis will be made of the new challenges that are being addressed, with a view to bringing about a more global integration. (authors)

Integrated Genome-Based Studies of Shewanella Ecophysiology

Energy Technology Data Exchange (ETDEWEB)

Andrei L. Osterman, Ph.D.

2012-12-17

Integration of bioinformatics and experimental techniques was applied to mapping and characterization of the key components (pathways, enzymes, transporters, regulators) of the core metabolic machinery in Shewanella oneidensis and related species with main focus was on metabolic and regulatory pathways involved in utilization of various carbon and energy sources. Among the main accomplishments reflected in ten joint publications with other participants of Shewanella Federation are: (i) A systems-level reconstruction of carbohydrate utilization pathways in the genus of Shewanella (19 species). This analysis yielded reconstruction of 18 sugar utilization pathways including 10 novel pathway variants and prediction of > 60 novel protein families of enzymes, transporters and regulators involved in these pathways. Selected functional predictions were verified by focused biochemical and genetic experiments. Observed growth phenotypes were consistent with bioinformatic predictions providing strong validation of the technology and (ii) Global genomic reconstruction of transcriptional regulons in 16 Shewanella genomes. The inferred regulatory network includes 82 transcription factors, 8 riboswitches and 6 translational attenuators. Of those, 45 regulons were inferred directly from the genome context analysis, whereas others were propagated from previously characterized regulons in other species. Selected regulatory predictions were experimentally tested. Integration of this analysis with microarray data revealed overall consistency and provided additional layer of interactions between regulons. All the results were captured in the new database RegPrecise, which is a joint development with the LBNL team. A more detailed analysis of the individual subsystems, pathways and regulons in Shewanella spp included bioinfiormatics-based prediction and experimental characterization of: (i) N-Acetylglucosamine catabolic pathway; (ii)Lactate utilization machinery; (iii) Novel Nrt

The informed application of building-integrated wind power

Energy Technology Data Exchange (ETDEWEB)

Breshears, J.; Briscoe, C. [Zimmer Gunsal Frasca Architects, Portland, OR (United States)

2009-07-01

This paper reported on an exercise that was undertaken to integrate small-scale wind turbines into the design of an urban high-rise in Portland, Oregon. Wind behaviour in the urban environment is very complex, as the flow of wind over and around buildings often triggers multiple transitions of the air from laminar flow to turbulent. The study documented the process of moving beyond a simplistic approach to a truly informed application of building-integrated wind generation. The 4 key issues addressed in the study process were quantifying the geographical wind regime; predicting wind flow over the building; turbine selection; and pragmatics regarding the design of roof mounting to accommodate structural loads and mitigate vibration. The results suggested that the turbine array should produce in the range of only 1 per cent of the electrical load of the building. 13 refs., 11 figs.

Iris recognition based on key image feature extraction.

Science.gov (United States)

Ren, X; Tian, Q; Zhang, J; Wu, S; Zeng, Y

2008-01-01

In iris recognition, feature extraction can be influenced by factors such as illumination and contrast, and thus the features extracted may be unreliable, which can cause a high rate of false results in iris pattern recognition. In order to obtain stable features, an algorithm was proposed in this paper to extract key features of a pattern from multiple images. The proposed algorithm built an iris feature template by extracting key features and performed iris identity enrolment. Simulation results showed that the selected key features have high recognition accuracy on the CASIA Iris Set, where both contrast and illumination variance exist.

Thawed chilled Barents Sea cod fillets in modified atmosphere packaging-application of multivariate data analysis to select key parameters in good manufacturing practice

DEFF Research Database (Denmark)

Bøknæs, Niels; Jensen, K.N.; Guldager, H.S.

2002-01-01

The purpose of the present study was to select key parameters in good manufacturing practice for production of thawed chilled modified atmosphere packed (MAP) cod (Gadus morhua) fillets. The effect of frozen storage temperature (-20 and -30 C), frozen storage period (3, 6, 9 and 12 mo) and chill...... storage periods up to 21 d at 2 C were evaluated for thawed MAP Barents Sea cod fillets. Sensory, chemical, microbiological and physical quality attributes were evaluated and multivariate data analysis (principal component analysis and partial least- squares regression) applied for identification of key...... storage was low for thawed MAP Barents Sea cod and this fish raw material seemed the more appropriate for production of thawed chilled MAP products. Frozen storage inactivation of the spoilage bacteria of Photobacterium phosphorcum was modest in Barnets Sea cod, possibly due to high trimethylamine oxide...

Integrated Supplier Selection Framework in a Resilient Construction Supply Chain: An Approach via Analytic Hierarchy Process (AHP and Grey Relational Analysis (GRA

Directory of Open Access Journals (Sweden)

Ting-Kwei Wang

2017-02-01

Full Text Available Construction supply chain management is a unique and problematic issue within the construction industry due to its inevitable external risks and variations. The resilience capability of a supplier is of significance in supplier selection; a supplier selected in the context of a resilient construction supply chain (RCSC is referred to in this research as a “resilient construction supplier”. This paper proposes a supplier selection framework tailored to effective information integration for supply chain management. The proposed framework works by integrating building information modeling (BIM and a geographic information system (GIS in a RCSC. BIM and GIS together provide highly transparent construction material information, enhanced supply chain status visualization, and workable access information for supplier selection. Supplier performance is evaluated via seventeen resilient criteria under a combined methodology consisting of the analytic hierarchy process (AHP and grey relational analysis (GRA; AHP and GRA weigh the criteria and rank the suppliers respectively. By varying the weightings given to each criterion, sensitivity analysis was conducted to identify the criteria of resilience which impact the selection priorities of suppliers. An illustrative example is also provided to show the overall process of the proposed framework.

Perspective: Size selected clusters for catalysis and electrochemistry

Science.gov (United States)

Halder, Avik; Curtiss, Larry A.; Fortunelli, Alessandro; Vajda, Stefan

2018-03-01

Size-selected clusters containing a handful of atoms may possess noble catalytic properties different from nano-sized or bulk catalysts. Size- and composition-selected clusters can also serve as models of the catalytic active site, where an addition or removal of a single atom can have a dramatic effect on their activity and selectivity. In this perspective, we provide an overview of studies performed under both ultra-high vacuum and realistic reaction conditions aimed at the interrogation, characterization, and understanding of the performance of supported size-selected clusters in heterogeneous and electrochemical reactions, which address the effects of cluster size, cluster composition, cluster-support interactions, and reaction conditions, the key parameters for the understanding and control of catalyst functionality. Computational modeling based on density functional theory sampling of local minima and energy barriers or ab initio molecular dynamics simulations is an integral part of this research by providing fundamental understanding of the catalytic processes at the atomic level, as well as by predicting new materials compositions which can be validated in experiments. Finally, we discuss approaches which aim at the scale up of the production of well-defined clusters for use in real world applications.

Handoff Triggering and Network Selection Algorithms for Load-Balancing Handoff in CDMA-WLAN Integrated Networks

Directory of Open Access Journals (Sweden)

Khalid Qaraqe

2008-10-01

Full Text Available This paper proposes a novel vertical handoff algorithm between WLAN and CDMA networks to enable the integration of these networks. The proposed vertical handoff algorithm assumes a handoff decision process (handoff triggering and network selection. The handoff trigger is decided based on the received signal strength (RSS. To reduce the likelihood of unnecessary false handoffs, the distance criterion is also considered. As a network selection mechanism, based on the wireless channel assignment algorithm, this paper proposes a context-based network selection algorithm and the corresponding communication algorithms between WLAN and CDMA networks. This paper focuses on a handoff triggering criterion which uses both the RSS and distance information, and a network selection method which uses context information such as the dropping probability, blocking probability, GoS (grade of service, and number of handoff attempts. As a decision making criterion, the velocity threshold is determined to optimize the system performance. The optimal velocity threshold is adjusted to assign the available channels to the mobile stations. The optimal velocity threshold is adjusted to assign the available channels to the mobile stations using four handoff strategies. The four handoff strategies are evaluated and compared with each other in terms of GOS. Finally, the proposed scheme is validated by computer simulations.

Handoff Triggering and Network Selection Algorithms for Load-Balancing Handoff in CDMA-WLAN Integrated Networks

Directory of Open Access Journals (Sweden)

Kim Jang-Sub

2008-01-01

Full Text Available This paper proposes a novel vertical handoff algorithm between WLAN and CDMA networks to enable the integration of these networks. The proposed vertical handoff algorithm assumes a handoff decision process (handoff triggering and network selection. The handoff trigger is decided based on the received signal strength (RSS. To reduce the likelihood of unnecessary false handoffs, the distance criterion is also considered. As a network selection mechanism, based on the wireless channel assignment algorithm, this paper proposes a context-based network selection algorithm and the corresponding communication algorithms between WLAN and CDMA networks. This paper focuses on a handoff triggering criterion which uses both the RSS and distance information, and a network selection method which uses context information such as the dropping probability, blocking probability, GoS (grade of service, and number of handoff attempts. As a decision making criterion, the velocity threshold is determined to optimize the system performance. The optimal velocity threshold is adjusted to assign the available channels to the mobile stations. The optimal velocity threshold is adjusted to assign the available channels to the mobile stations using four handoff strategies. The four handoff strategies are evaluated and compared with each other in terms of GOS. Finally, the proposed scheme is validated by computer simulations.

Selection Ideal Coal Suppliers of Thermal Power Plants Using the Matter-Element Extension Model with Integrated Empowerment Method for Sustainability

Directory of Open Access Journals (Sweden)

Zhongfu Tan

2014-01-01

Full Text Available In order to reduce thermal power generation cost and improve its market competitiveness, considering fuel quality, cost, creditworthiness, and sustainable development capacity factors, this paper established the evaluation system for coal supplier selection of thermal power and put forward the coal supplier selection strategies for thermal power based on integrated empowering and ideal matter-element extension models. On the one hand, the integrated empowering model can overcome the limitations of subjective and objective methods to determine weights, better balance subjective, and objective information. On the other hand, since the evaluation results of the traditional element extension model may fall into the same class and only get part of the order results, in order to overcome this shortcoming, the idealistic matter-element extension model is constructed. It selects the ideal positive and negative matter-elements classical field and uses the closeness degree to replace traditional maximum degree of membership criterion and calculates the positive or negative distance between the matter-element to be evaluated and the ideal matter-element; then it can get the full order results of the evaluation schemes. Simulated and compared with the TOPSIS method, Romania selection method, and PROMETHEE method, numerical example results show that the method put forward by this paper is effective and reliable.

Selection of Sustainable Technology for VOC Abatement in an Industry: An Integrated AHP-QFD Approach

Science.gov (United States)

Gupta, Alok Kumar; Modi, Bharat A.

2018-04-01

Volatile organic compounds (VOCs) are universally present in global atmospheric pollutants. These VOCs are responsible for photo chemical reaction in atmosphere leading to serious harmful effects on human health and environment. VOCs are produced from both natural and man-made sources and may have good commercial value if it can be utilized as alternate fuel. As per data from US EPA, 15% of total VOC emissions are generated from surface coating industry but VOC concentration and exhaust air volume varies to a great extent and is dependent on processes used by industry. Various technologies are available for abatement of VOCs. Physical, Chemical and Biological technologies are available to remove VOCs by either recovery or destruction with many advantages and limitations. With growing environmental awareness and considering the resource limitations of medium and small scale industries, requirement of a tool for selecting appropriate techno economically viable solution for removal of VOCs from industrial process exhaust is envisaged. The aim of the present study is to provide management a tool to determine the overall effect of implementation of VOC abatement technology on business performance and VOC emissions. The primary purpose of this work is to outline a methodology to rate various VOC abatement technologies with respect to the constraint of meeting current and foreseeable future regulatory requirements, operational flexibility and Over All Economics Parameters considering conservation of energy. In this paper an integrated approach has been proposed to select most appropriate abatement technology strategically. Analytical hierarchy process and Quality function deployment have been integrated for Techno-commercial evaluation. A case study on selection of VOC abatement technology for a leading aluminium foil surface coating, lamination and printing facility using this methodology is presented in this study.

Selective Gene Delivery for Integrating Exogenous DNA into Plastid and Mitochondrial Genomes Using Peptide-DNA Complexes.

Science.gov (United States)

Yoshizumi, Takeshi; Oikawa, Kazusato; Chuah, Jo-Ann; Kodama, Yutaka; Numata, Keiji

2018-05-14

Selective gene delivery into organellar genomes (mitochondrial and plastid genomes) has been limited because of a lack of appropriate platform technology, even though these organelles are essential for metabolite and energy production. Techniques for selective organellar modification are needed to functionally improve organelles and produce transplastomic/transmitochondrial plants. However, no method for mitochondrial genome modification has yet been established for multicellular organisms including plants. Likewise, modification of plastid genomes has been limited to a few plant species and algae. In the present study, we developed ionic complexes of fusion peptides containing organellar targeting signal and plasmid DNA for selective delivery of exogenous DNA into the plastid and mitochondrial genomes of intact plants. This is the first report of exogenous DNA being integrated into the mitochondrial genomes of not only plants, but also multicellular organisms in general. This fusion peptide-mediated gene delivery system is a breakthrough platform for both plant organellar biotechnology and gene therapy for mitochondrial diseases in animals.

A New Key-lock Method for User Authentication and Access Control

Institute of Scientific and Technical Information of China (English)

JI Dongyao; ZHANG Futai; WANG Yumin

2001-01-01

We propose a new key-lock methodfor user authentication and access control based onChinese remainder theorem, the concepts of the ac-cess control matrix, key-lock-pair, time stamp, and the NS public key protocol. Our method is dynamicand needs a minimum amount of computation in thesense that it only updates at most one key/lock foreach access request. We also demonstrate how an au-thentication protocol can be integrated into the ac-cess control method. By applying a time stamp, themethod can not only withstand replay attack, butalso strengthen the authenticating mechanism, whichcould not be achieved simultaneously in previous key-lock methods.

Tinjauan Konseptual: Criteria Suplier-Selection, Integrasi Internal dan Eksternal Supply Chain terhadap Kinerja Perusahaan

Directory of Open Access Journals (Sweden)

Endar Pituringsih

2010-08-01

Full Text Available Performance measurement reflects the company capability to prepare for the customer desired standard while it considers lower production and maintenance costs, higher product quality, reduced stock in process, deprived material processing cost, and shorter delivery deadline. Meanwhile, Supply Chain Management (SCM has important meaning to empower consumer in maximizing customer value. Supply Chain Management (SCM requires: internal integration (intra-organization and external integration (inter-organization. Primary key of Supply Chain Management (SCM will be having supplier as partner in the company strategy and satisfying the always changing market demand. Therefore, a selection among company strategy options in the global competition really produces a model of dominant integration, coordination, and cooperation in controlling global market, precisely through supply chain as important element to contribute to company performance improvement.

Contact Selectivity Engineering in a 2 μm Thick Ultrathin c-Si Solar Cell Using Transition-Metal Oxides Achieving an Efficiency of 10.8.

Science.gov (United States)

Xue, Muyu; Islam, Raisul; Meng, Andrew C; Lyu, Zheng; Lu, Ching-Ying; Tae, Christian; Braun, Michael R; Zang, Kai; McIntyre, Paul C; Kamins, Theodore I; Saraswat, Krishna C; Harris, James S

2017-12-06

In this paper, the integration of metal oxides as carrier-selective contacts for ultrathin crystalline silicon (c-Si) solar cells is demonstrated which results in an ∼13% relative improvement in efficiency. The improvement in efficiency originates from the suppression of the contact recombination current due to the band offset asymmetry of these oxides with Si. First, an ultrathin c-Si solar cell having a total thickness of 2 μm is shown to have >10% efficiency without any light-trapping scheme. This is achieved by the integration of nickel oxide (NiO x ) as a hole-selective contact interlayer material, which has a low valence band offset and high conduction band offset with Si. Second, we show a champion cell efficiency of 10.8% with the additional integration of titanium oxide (TiO x ), a well-known material for an electron-selective contact interlayer. Key parameters including V oc and J sc also show different degrees of enhancement if single (NiO x only) or double (both NiO x and TiO x ) carrier-selective contacts are integrated. The fabrication process for TiO x and NiO x layer integration is scalable and shows good compatibility with the device.

Key Ingredients-Target Groups, Methods and Messages, and Evaluation-of Local-Level, Public Interventions to Counter Stigma and Discrimination: A Lived Experience Informed Selective Narrative Literature Review.

Science.gov (United States)

Ashton, Laura J; Gordon, Sarah E; Reeves, Racheal A

2018-04-01

A proliferation of recent literature provides substantial direction as to the key ingredients-target groups, messages and methods, and evaluation-of local-level, public interventions to counter stigma and discrimination. This paper provides a selective narrative review of that literature from the perspective or standpoint of anti-stigma experts with lived experience of mental distress, the key findings of which have been synthesised and presented in diagrammatic overviews (infographics). These are intended to guide providers in planning, delivering and evaluating lived experience-directed local-level, public interventions to counter stigma and discrimination in accord with current best practice.

Integrated test schedule for buried waste integrated demonstration

International Nuclear Information System (INIS)

Brown, J.T.; McDonald, J.K.

1992-05-01

The Integrated Test Schedule incorporates the various schedules the Buried Waste Integrated Demonstration (BWID) supports into one document. This document contains the Federal Facilities Agreement and Consent Order schedules for the Idaho National Engineering Laboratory, Hanford Reservation, Oak Ridge Reservation, and Fernald Environmental Materials Center. Included in the Integrated Test Schedule is the Buried Waste Integrated Demonstration ''windows of opportunity'' schedule. The ''windows of opportunity'' schedule shows periods of time in which Buried Waste Integrated Demonstration Program-sponsored technology demonstrations could support key decisions in the Federal Facilities Agreement and Consent Order. Schedules for the Buried Waste Integrated Demonstration-sponsored technology task plans are categorized by technology area and divided by current fiscal year and out-year. Total estimated costs for Buried Waste Integrated Demonstration-sponsored Technology Task Plans for FY-92 through FY-97 are $74.756M

Key directions of the Russian economy innovative development with the innovative activity practice of the integrated corporate structures

Directory of Open Access Journals (Sweden)

F. I. Shamhalov

2016-01-01

Full Text Available The article deals with the problems and the key directions of The article deals with the problems and key directions of innovative development of the Russian industry in connection with the need to reduce the dependence of the national economy on the situation on world commodity markets, as well as to create the conditions and incentives for the introduction and modern technologies development, improving energy and environmental efficiency of the economy and productivity for the development of economic sectors and industries, producing goods with high added value for the implementation of innovative projects and in general - to upgrade the socio-economic system of the country.The following statement is given: the development of innovative high-tech and knowledge-intensive industries must ensure import substitution products at the first stage, primarily in the militaryindustrial complex, and in the future - export-oriented competitive product.The article analyzes the experience of innovative activity of the integrated corporate structures with the participation of the state in the following areas: the integration of the industrial and financial capital; the concentration of capital (through the merger and acquisition of enterprises, strategic alliances; diversification of forms and fields of activity; globalization of activities (creation of subsidiaries in the most attractive countries and working on promising markets; capital internationalization (through the creation of transnational companies.On the basis of generalization of global corporate management experience in the state corporations the article analyzes key conditions and factors that determine the efficiency of the state-owned companies as a whole: a clear statement of goals and objectives of the state as the owner, whose interests go beyond the usual business purposes; fixing of these goals and objectives in the regulations, in the concepts and programs of long-term socioeconomic

Glutamine 57 at the complementary binding site face is a key determinant of morantel selectivity for {alpha}7 nicotinic receptors.

Science.gov (United States)

Bartos, Mariana; Price, Kerry L; Lummis, Sarah C R; Bouzat, Cecilia

2009-08-07

Nicotinic receptors (AChRs) play key roles in synaptic transmission. We explored activation of neuronal alpha7 and mammalian muscle AChRs by morantel and oxantel. Our results revealed a novel action of morantel as a high efficacy and more potent agonist than ACh of alpha7 receptors. The EC(50) for activation by morantel of both alpha7 and alpha7-5HT(3A) receptors is 7-fold lower than that determined for ACh. The minimum morantel concentration required to activate alpha7-5HT(3A) channels is 6-fold lower than that of ACh, and activation episodes are more prolonged than in the presence of ACh. By contrast, oxantel is a weak agonist of alpha7 and alpha7-5HT(3A), and both drugs are very low efficacy agonists of muscle AChRs. The replacement of Gln(57) in alpha7 by glycine, which is found in the equivalent position of the muscle AChR, decreases the efficacy for activation and turns morantel into a partial agonist. The reverse mutation in the muscle AChR (epsilonG57Q) increases 7-fold the efficacy of morantel. The mutations do not affect activation by ACh or oxantel, indicating that this position is selective for morantel. In silico studies show that the tetrahydropyrimidinyl group, common to both drugs, is close to Trp(149) of the principal face of the binding site, whereas the other cyclic group is proximal to Gln(57) of the complementary face in morantel but not in oxantel. Thus, position 57 at the complementary face is a key determinant of the high selectivity of morantel for alpha7. These results provide new information for further progress in drug design.

FPGA BASED HARDWARE KEY FOR TEMPORAL ENCRYPTION

Directory of Open Access Journals (Sweden)

B. Lakshmi

2010-09-01

Full Text Available In this paper, a novel encryption scheme with time based key technique on an FPGA is presented. Time based key technique ensures right key to be entered at right time and hence, vulnerability of encryption through brute force attack is eliminated. Presently available encryption systems, suffer from Brute force attack and in such a case, the time taken for breaking a code depends on the system used for cryptanalysis. The proposed scheme provides an effective method in which the time is taken as the second dimension of the key so that the same system can defend against brute force attack more vigorously. In the proposed scheme, the key is rotated continuously and four bits are drawn from the key with their concatenated value representing the delay the system has to wait. This forms the time based key concept. Also the key based function selection from a pool of functions enhances the confusion and diffusion to defend against linear and differential attacks while the time factor inclusion makes the brute force attack nearly impossible. In the proposed scheme, the key scheduler is implemented on FPGA that generates the right key at right time intervals which is then connected to a NIOS – II processor (a virtual microcontroller which is brought out from Altera FPGA that communicates with the keys to the personal computer through JTAG (Joint Test Action Group communication and the computer is used to perform encryption (or decryption. In this case the FPGA serves as hardware key (dongle for data encryption (or decryption.

The Benchmarking of Integrated Business Structures

Directory of Open Access Journals (Sweden)

Nifatova Olena M.

2017-12-01

Full Text Available The aim of the article is to study the role of the benchmarking in the process of integration of business structures in the aspect of knowledge sharing. The results of studying the essential content of the concept “integrated business structure” and its semantic analysis made it possible to form our own understanding of this category with an emphasis on the need to consider it in the plane of three projections — legal, economic and organizational one. The economic projection of the essential content of integration associations of business units is supported by the organizational projection, which is expressed through such essential aspects as existence of a single center that makes key decisions; understanding integration as knowledge sharing; using the benchmarking as exchange of experience on key business processes. Understanding the process of integration of business units in the aspect of knowledge sharing involves obtaining certain information benefits. Using the benchmarking as exchange of experience on key business processes in integrated business structures will help improve the basic production processes, increase the efficiency of activity of both the individual business unit and the IBS as a whole.

Methodology for Selecting Best Management Practices Integrating Multiple Stakeholders and Criteria. Part 1: Methodology

Directory of Open Access Journals (Sweden)

Mauricio Carvallo Aceves

2016-02-01

Full Text Available The implementation of stormwater Best Management Practices (BMPs could help re-establish the natural hydrological cycle of watersheds after urbanization, with each BMP presenting a different performance across a range of criteria (flood prevention, pollutant removal, etc.. Additionally, conflicting views from the relevant stakeholders may arise, resulting in a complex selection process. This paper proposes a methodology for BMP selection based on the application of multi-criteria decision aid (MCDA methods, integrating multiple stakeholder priorities and BMP combinations. First, in the problem definition, the MCDA methods, relevant criteria and design guidelines are selected. Next, information from the preliminary analysis of the watershed is used to obtain a list of relevant BMPs. The third step comprises the watershed modeling and analysis of the BMP alternatives to obtain performance values across purely objective criteria. Afterwards, a stakeholder analysis based on survey applications is carried out to obtain social performance values and criteria priorities. Then, the MCDA methods are applied to obtain the final BMP rankings. The last step considers the sensitivity analysis and rank comparisons in order to draw the final conclusions and recommendations. Future improvements to the methodology could explore inclusion of multiple objective analysis, and alternative means for obtaining social performance values.

An Integrated MCDM Method in Ranking BSC Perspectives and key Performance Indicators (KPIs

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Mohsen Alvandi

2012-04-01

Full Text Available The balanced scorecard (BSC approach is an effective technique for performance evaluation. BSC can better reflect the dependence and feedback problems of each factor in real world situations. This study aims at developing a set of appropriate key performance indicators according to (BSC approach for SAPCO using multiple criteria decision making(MCDM method. We provide key performance indicators through literature reviews and experts' idea in SAPCO, which is one of the biggest vehicle spare suppliers in Iran. The proposed study uses decision making trial and evaluation laboratory (DEMATEL and analytic network process (ANP, respectively to measure the casual relationship between the perspectives as well as the relative weights. The results based on ANP method shows that ‘‘Customer’’ is the most influential factor. In addition, internal process, financial and learning and growth are in two to four positions. Three important key performance indicators are as bellow: Total price of parts, Customer satisfaction and Lack of parts in production.

Progress on water data integration and distribution: a summary of select U.S. Geological Survey data systems

Science.gov (United States)

Blodgett, David L.; Lucido, Jessica M.; Kreft, James M.

2016-01-01

Critical water-resources issues ranging from flood response to water scarcity make access to integrated water information, services, tools, and models essential. Since 1995 when the first water data web pages went online, the U.S. Geological Survey has been at the forefront of water data distribution and integration. Today, real-time and historical streamflow observations are available via web pages and a variety of web service interfaces. The Survey has built partnerships with Federal and State agencies to integrate hydrologic data providing continuous observations of surface and groundwater, temporally discrete water quality data, groundwater well logs, aquatic biology data, water availability and use information, and tools to help characterize the landscape for modeling. In this paper, we summarize the status and design patterns implemented for selected data systems. We describe how these systems contribute to a U.S. Federal Open Water Data Initiative and present some gaps and lessons learned that apply to global hydroinformatics data infrastructure.

Fibre optic communication key devices

CERN Document Server

Grote, Norbert

2017-01-01

The book gives an in-depth description of key devices of current and next generation fibre optic communication networks. Devices treated include semiconductor lasers, optical amplifiers, modulators, wavelength filters and other passives, detectors, all-optical switches, but relevant properties of optical fibres and network aspects are included as well. The presentations include the physical principles underlying the various devices, technologies used for their realization, typical performance characteristics and limitations, but development trends towards more advanced components are also illustrated. This new edition of a successful book was expanded and updated extensively. The new edition covers among others lasers for optical communication, optical switches, hybrid integration, monolithic integration and silicon photonics. The main focus is on Indium phosphide-based structures but silicon photonics is included as well. The book covers relevant principles, state-of-the-art implementations, status of curren...

Flexible Web services integration: a novel personalised social approach

Science.gov (United States)

Metrouh, Abdelmalek; Mokhati, Farid

2018-05-01

Dynamic composition or integration remains one of the key objectives of Web services technology. This paper aims to propose an innovative approach of dynamic Web services composition based on functional and non-functional attributes and individual preferences. In this approach, social networks of Web services are used to maintain interactions between Web services in order to select and compose Web services that are more tightly related to user's preferences. We use the concept of Web services community in a social network of Web services to reduce considerably their search space. These communities are created by the direct involvement of Web services providers.

A key review of building integrated photovoltaic (BIPV systems

Directory of Open Access Journals (Sweden)

Emrah Biyik

2017-06-01

The two fundamental research areas in the BIPV and BIPVT systems are observed to be i improvements on system efficiency by ventilation, hence obtaining a higher yield with lowering the panel temperature ii new thin film technologies that are well suited for building integration. Several approaches to achieve these objectives are reported in the literature as presented in this paper. It is expected that this comprehensive review will be beneficial to researchers and practitioners involved or interested in the design, analysis, simulation, and performance evaluation, financial development and incentives, new methods and trends of BIPV systems.

Expected value analysis for integrated supplier selection and inventory control of multi-product inventory system with fuzzy cost

Science.gov (United States)

Sutrisno, Widowati, Tjahjana, R. Heru

2017-12-01

The future cost in many industrial problem is obviously uncertain. Then a mathematical analysis for a problem with uncertain cost is needed. In this article, we deals with the fuzzy expected value analysis to solve an integrated supplier selection and supplier selection problem with uncertain cost where the costs uncertainty is approached by a fuzzy variable. We formulate the mathematical model of the problems fuzzy expected value based quadratic optimization with total cost objective function and solve it by using expected value based fuzzy programming. From the numerical examples result performed by the authors, the supplier selection problem was solved i.e. the optimal supplier was selected for each time period where the optimal product volume of all product that should be purchased from each supplier for each time period was determined and the product stock level was controlled as decided by the authors i.e. it was followed the given reference level.

Integrated bioinformatics analysis reveals key candidate genes and pathways in breast cancer.

Science.gov (United States)

Wang, Yuzhi; Zhang, Yi; Huang, Qian; Li, Chengwen

2018-04-19

Breast cancer (BC) is the leading malignancy in women worldwide, yet relatively little is known about the genes and signaling pathways involved in BC tumorigenesis and progression. The present study aimed to elucidate potential key candidate genes and pathways in BC. Five gene expression profile data sets (GSE22035, GSE3744, GSE5764, GSE21422 and GSE26910) were downloaded from the Gene Expression Omnibus (GEO) database, which included data from 113 tumorous and 38 adjacent non‑tumorous tissue samples. Differentially expressed genes (DEGs) were identified using t‑tests in the limma R package. These DEGs were subsequently investigated by pathway enrichment analysis and a protein‑protein interaction (PPI) network was constructed. The most significant module from the PPI network was selected for pathway enrichment analysis. In total, 227 DEGs were identified, of which 82 were upregulated and 145 were downregulated. Pathway enrichment analysis results revealed that the upregulated DEGs were mainly enriched in 'cell division', the 'proteinaceous extracellular matrix (ECM)', 'ECM structural constituents' and 'ECM‑receptor interaction', whereas downregulated genes were mainly enriched in 'response to drugs', 'extracellular space', 'transcriptional activator activity' and the 'peroxisome proliferator‑activated receptor signaling pathway'. The PPI network contained 174 nodes and 1,257 edges. DNA topoisomerase 2‑a, baculoviral inhibitor of apoptosis repeat‑containing protein 5, cyclin‑dependent kinase 1, G2/mitotic‑specific cyclin‑B1 and kinetochore protein NDC80 homolog were identified as the top 5 hub genes. Furthermore, the genes in the most significant module were predominantly involved in 'mitotic nuclear division', 'mid‑body', 'protein binding' and 'cell cycle'. In conclusion, the DEGs, relative pathways and hub genes identified in the present study may aid in understanding of the molecular mechanisms underlying BC progression and provide

An Integrated Glucose Sensor with an All-Solid-State Sodium Ion-Selective Electrode for a Minimally Invasive Glucose Monitoring System

Directory of Open Access Journals (Sweden)

Junko Kojima

2015-06-01

Full Text Available We developed a minimally invasive glucose monitoring system that uses a microneedle to permeate the skin surface and a small hydrogel to accumulate interstitial fluid glucose. The measurement of glucose and sodium ion levels in the hydrogel is required for estimating glucose levels in blood; therefore, we developed a small, enzyme-fixed glucose sensor with a high-selectivity, all-solid-state, sodium ion-selective electrode (ISE integrated into its design. The glucose sensor immobilized glucose oxidase showed a good correlation between the glucose levels in the hydrogels and the reference glucose levels (r > 0.99, and exhibited a good precision (coefficient of variation = 2.9%, 0.6 mg/dL. In the design of the sodium ISEs, we used the insertion material Na0.33MnO2 as the inner contact layer and DD16C5 exhibiting high Na+/K+ selectivity as the ionophore. The developed sodium ISE exhibited high selectivity (\\( \\log \\,k^{pot}_{Na,K} = -2.8\\ and good potential stability. The sodium ISE could measure 0.4 mM (10−3.4 M sodium ion levels in the hydrogels containing 268 mM (10−0.57 M KCl. The small integrated sensor (ϕ < 10 mm detected glucose and sodium ions in hydrogels simultaneously within 1 min, and it exhibited sufficient performance for use as a minimally invasive glucose monitoring system.

Anonymity-Preserving Public-Key Encryption

DEFF Research Database (Denmark)

Kohlweiss, Markulf; Maurer, Ueli; Onete, Cristina

2013-01-01

security properties have been proposed. We investigate constructions as well as limitations for preserving receiver anonymity when using public-key encryption (PKE). We use the constructive cryptography approach by Maurer and Renner and interpret cryptographic schemes as constructions of a certain ideal...... literature (IND-CCA, key-privacy, weak robustness). We also show that a desirable stronger variant, preventing the adversary from selective ”trial-deliveries” of messages, is unfortunately unachievable by any PKE scheme, no matter how strong. The constructive approach makes the guarantees achieved...... by applying a cryptographic scheme explicit in the constructed (ideal) resource; this specifies the exact requirements for the applicability of a cryptographic scheme in a given context. It also allows to decide which of the existing security properties of such a cryptographic scheme are adequate...

Community landscapes: an integrative approach to determine overlapping network module hierarchy, identify key nodes and predict network dynamics.

Directory of Open Access Journals (Sweden)

István A Kovács

Full Text Available BACKGROUND: Network communities help the functional organization and evolution of complex networks. However, the development of a method, which is both fast and accurate, provides modular overlaps and partitions of a heterogeneous network, has proven to be rather difficult. METHODOLOGY/PRINCIPAL FINDINGS: Here we introduce the novel concept of ModuLand, an integrative method family determining overlapping network modules as hills of an influence function-based, centrality-type community landscape, and including several widely used modularization methods as special cases. As various adaptations of the method family, we developed several algorithms, which provide an efficient analysis of weighted and directed networks, and (1 determine persvasively overlapping modules with high resolution; (2 uncover a detailed hierarchical network structure allowing an efficient, zoom-in analysis of large networks; (3 allow the determination of key network nodes and (4 help to predict network dynamics. CONCLUSIONS/SIGNIFICANCE: The concept opens a wide range of possibilities to develop new approaches and applications including network routing, classification, comparison and prediction.

Parallel Device-Independent Quantum Key Distribution

OpenAIRE

Jain, Rahul; Miller, Carl A.; Shi, Yaoyun

2017-01-01

A prominent application of quantum cryptography is the distribution of cryptographic keys with unconditional security. Recently, such security was extended by Vazirani and Vidick (Physical Review Letters, 113, 140501, 2014) to the device-independent (DI) scenario, where the users do not need to trust the integrity of the underlying quantum devices. The protocols analyzed by them and by subsequent authors all require a sequential execution of N multiplayer games, where N is the security parame...

The Integration of Extended Supply Chain with Sales and Operation Planning: A Conceptual Framework

Directory of Open Access Journals (Sweden)

Md. Rokonuzzaman

2018-03-01

Full Text Available This research is an effort to present the emergence of ways to enable marketers to attain high sensitivity and visibility in the supply chain network. It also aims to facilitate better multi-criteria decisions throughout the extended supply chain. It is a qualitative study considering 31 published research articles related to supply chain integration, sales and operation planning, and the use of information systems. With a focus on narrative data, a purposive sampling technique was used to select the papers for review and to produce the results of this study. The findings of this research indicate that the sales and operation planning (S&OP processes and the key operations in the supply chain network need to be fully integrated. The findings also indicate that information system resources are the key enabler of S&OP and supply chain integration. To be specific, this research is an exercise in theorizing a conceptual framework for optimally confronting the emerging challenges and opportunities regarding an extended supply chain and is intended to bring the proficiency of multi-criteria decisions and actions in the entire supply chain network.

The mechanosensory calcium-selective ion channel: key component of a plasmalemmal control centre?

Science.gov (United States)

Pickard, B. G.; Ding, J. P.

1993-01-01

Mechanosensory calcium-selective ion channels probably serve to detect not only mechanical stress but also electrical, thermal, and diverse chemical stimuli. Because all stimuli result in a common output, most notably a shift in second messenger calcium concentration, the channels are presumed to serve as signal integrators. Further, insofar as second messenger calcium in turn gives rise to mechanical, electrical, and diverse chemical changes, the channels are postulated to initiate regulatory feedbacks. It is proposed that the channels and the feedback loops play a wide range of roles in regulating normal plant function, as well as in mediating disturbance of normal function by environmental stressors and various pathogens. In developing evidence for the physiological performance of the channel, a model for a cluster of regulatory plasmalemmal proteins and cytoskeletal elements grouped around a set of wall-to-membrane and transmembrane linkers has proved useful. An illustration of how the model might operate is presented. It is founded on the demonstration that several xenobiotics interfere both with normal channel behaviour and with gravitropic reception. Accordingly, the first part of the illustration deals with how the channels and the control system within which they putatively operate might initiate gravitropism. Assuming that gravitropism is an asymmetric expression of growth, the activities of the channels and the plasmalemmal control system are extrapolated to account for regulation of both rate and allometry of cell expansion. Finally, it is discussed how light, hormones, redox agents and herbicides could in principle affect growth via the putative plasmalemmal control cluster or centre.

Improvement of non-key traits in radiata pine breeding programme when long-term economic importance is uncertain.

Science.gov (United States)

Li, Yongjun; Dungey, Heidi; Yanchuk, Alvin; Apiolaza, Luis A

2017-01-01

Diameter at breast height (DBH), wood density (DEN) and predicted modulus of elasticity (PME) are considered as 'key traits' (KT) in the improvement in radiata pine breeding programmes in New Zealand. Any other traits which are also of interest to radiata pine breeders and forest growers are called 'non-key traits' (NKTs). External resin bleeding (ERB), internal checking (IC), number of heartwood rings (NHR) are three such non-key traits which affect wood quality of radiata pine timber. Economic importance of the KTs and NKTs is hard to define in radiata pine breeding programmes due to long rotation period. Desired-gain index (DGIs) and robust selection were proposed to incorporate NKTs into radiata pine breeding programme in order to deal with the uncertainty of economic importance. Four desired-gain indices A-D were proposed in this study. The desired-gain index A (DGI-A) emphasized growth and led to small decrease in ERB and small increase in IC and NHR. The expected genetic gains of all traits in the desired-gain index B (DGI-B) were in the favourable directions (positive genetic gains in the key traits and negative genetic gains in the non-key traits). The desired-gain index C (DGI-C) placed emphasis on wood density, leading to favourable genetic gain in the NKTs but reduced genetic gains for DBH and PME. The desired-gain index D (DGI-D) exerted a bit more emphasis on the non-key traits, leading large favourable reduction in the non-key traits and lower increase in the key traits compared with the other DGIs. When selecting both the key traits and the non-key traits, the average EBVs of six traits were all in the same directions as the expected genetic gains except for DBH in the DGI-D. When the key traits were measured and selected, internal checking always had a negative (favourable) genetic gain but ERB and NHR had unfavourable genetic gain in the most of time. After removing some individuals with high sensitivity to the change of economic weights, robust

Improvement of non-key traits in radiata pine breeding programme when long-term economic importance is uncertain.

Directory of Open Access Journals (Sweden)

Yongjun Li

Full Text Available Diameter at breast height (DBH, wood density (DEN and predicted modulus of elasticity (PME are considered as 'key traits' (KT in the improvement in radiata pine breeding programmes in New Zealand. Any other traits which are also of interest to radiata pine breeders and forest growers are called 'non-key traits' (NKTs. External resin bleeding (ERB, internal checking (IC, number of heartwood rings (NHR are three such non-key traits which affect wood quality of radiata pine timber. Economic importance of the KTs and NKTs is hard to define in radiata pine breeding programmes due to long rotation period. Desired-gain index (DGIs and robust selection were proposed to incorporate NKTs into radiata pine breeding programme in order to deal with the uncertainty of economic importance. Four desired-gain indices A-D were proposed in this study. The desired-gain index A (DGI-A emphasized growth and led to small decrease in ERB and small increase in IC and NHR. The expected genetic gains of all traits in the desired-gain index B (DGI-B were in the favourable directions (positive genetic gains in the key traits and negative genetic gains in the non-key traits. The desired-gain index C (DGI-C placed emphasis on wood density, leading to favourable genetic gain in the NKTs but reduced genetic gains for DBH and PME. The desired-gain index D (DGI-D exerted a bit more emphasis on the non-key traits, leading large favourable reduction in the non-key traits and lower increase in the key traits compared with the other DGIs. When selecting both the key traits and the non-key traits, the average EBVs of six traits were all in the same directions as the expected genetic gains except for DBH in the DGI-D. When the key traits were measured and selected, internal checking always had a negative (favourable genetic gain but ERB and NHR had unfavourable genetic gain in the most of time. After removing some individuals with high sensitivity to the change of economic weights

Parasites as drivers of key processes in aquatic ecosystems: Facts and future directions.

Science.gov (United States)

Sures, B; Nachev, M; Pahl, M; Grabner, D; Selbach, C

2017-09-01

Despite the advances in our understanding of the ecological importance of parasites that we have made in recent years, we are still far away from having a complete picture of the ecological implications connected to parasitism. In the present paper we highlight key issues that illustrate (1) important contributions of parasites to biodiversity, (2) their integral role in ecosystems, (3) as well as their ecological effects as keystone species (4) and in biological invasion processes. By using selected examples from aquatic ecosystems we want to provide an insight and generate interest into the topic, and want to show directions for future research in the field of ecological parasitology. This may help to convince more parasitologists and ecologists contributing and advancing our understanding of the complex and fascinating interplay of parasites, hosts and ecosystems. Copyright © 2017 Elsevier Inc. All rights reserved.

Noise tolerance in wavelength-selective switching of optical differential quadrature-phase-shift-keying pulse train by collinear acousto-optic devices.

Science.gov (United States)

Goto, Nobuo; Miyazaki, Yasumitsu

2014-06-01

Optical switching of high-bit-rate quadrature-phase-shift-keying (QPSK) pulse trains using collinear acousto-optic (AO) devices is theoretically discussed. Since the collinear AO devices have wavelength selectivity, the switched optical pulse trains suffer from distortion when the bandwidth of the pulse train is comparable to the pass bandwidth of the AO device. As the AO device, a sidelobe-suppressed device with a tapered surface-acoustic-wave (SAW) waveguide and a Butterworth-type filter device with a lossy SAW directional coupler are considered. Phase distortion of optical pulse trains at 40 to 100  Gsymbols/s in QPSK format is numerically analyzed. Bit-error-rate performance with additive Gaussian noise is also evaluated by the Monte Carlo method.

Integrated GIS-Based Site Selection of Hillside Development for Future Growth of Urban Areas

Directory of Open Access Journals (Sweden)

Imtiaz Ahmed Chandio

2016-04-01

Full Text Available Urbanization is a challenging issue for developing countries, like Malaysia. Penang Island is one of the states of Malaysia selected as a study area where limited flat land exists. As a result, this would create urban environmental problems, such as unstable slopes and landslides due to uneven topography. The purpose of this study was to develop land suitability model for hillside development. Hence, this research aims land suitability analysis modelling for hillside development by using integrated GIS (Geographic Information System based MCDM (Multi-Criteria Decision Making approach. The hill land portion of Penang Island was selected for hillside site development using GIS and AHP (Analytic Hierarchy Process as a MCDM method for sustainable hillside development. This study found that 15% of land was highly suitable, 27% moderately suitable, 41% less suitable, and 17% not suitable. Therefore, this research can be consistently used by the concerned authorities for sustainable hillside urban planning and development. This approach can be used as a policy tool in decision making of urban planning and development.

Integrated Community Energy Systems: engineering analysis and design bibliography. [368 citations

Energy Technology Data Exchange (ETDEWEB)

Calm, J.M.; Sapienza, G.R.

1979-05-01

This bibliography cites 368 documents that may be helpful in the planning, analysis, and design of Integrated Community Energy Systems. It has been prepared for use primarily by engineers and others involved in the development and implementation of ICES concepts. These documents include products of a number of Government research, development, demonstration, and commercialization programs; selected studies and references from the literature of various technical societies and institutions; and other selected material. The key programs which have produced cited reports are the Department of Energy Community Systems Program (DOE/CSP), the Department of Housing and Urban Development Modular Integrated Utility Systems Program (HUD/MIUS), and the Department of Health, Education, and Welfare Integrated Utility Systems Program (HEW/IUS). The cited documents address experience gained both in the U.S. and in other countries. Several general engineering references and bibliographies pertaining to technologies or analytical methods that may be helpful in the analysis and design of ICES are also included. The body of relevant literature is rapidly growing and future updates are therefore planned. Each citation includes identifying information, a source, descriptive information, and an abstract. The citations are indexed both by subjects and authors, and the subject index is extensively cross-referenced to simplify its use.

Handling equipment Selection in open pit mines by using an integrated model based on group decision making

Directory of Open Access Journals (Sweden)

Abdolreza Yazdani-Chamzini

2012-10-01

Full Text Available Process of handling equipment selection is one of the most important and basic parts in the project planning, particularly mining projects due to holding a high charge of the total project's cost. Different criteria impact on the handling equipment selection, while these criteria often are in conflicting with each other. Therefore, the process of handling equipment selection is a complex and multi criteria decision making problem. There are a variety of methods for selecting the most appropriate equipment among a set of alternatives. Likewise, according to the sophisticated structure of the problem, imprecise data, less of information, and inherent uncertainty, the usage of the fuzzy sets can be useful. In this study a new integrated model based on fuzzy analytic hierarchy process (FAHP and fuzzy technique for order preference by similarity to ideal solution (FTOPSIS is proposed, which uses group decision making to reduce individual errors. In order to calculate the weights of the evaluation criteria, FAHP is utilized in the process of handling equipment selection, and then these weights are inserted to the FTOPSIS computations to select the most appropriate handling system among a pool of alternatives. The results of this study demonstrate the potential application and effectiveness of the proposed model, which can be applied to different types of sophisticated problems in real problems.

The social-financial responsible reporting – the key for integrated reporting

Directory of Open Access Journals (Sweden)

Iulia Jianu

2012-08-01

Full Text Available General purpose of financial statements is to satisfy the needs of users who are not in the position to require of the entity to prepare reports tailored to their particular information needs. Because the public is one of these users interested of social information and because the financial statement do not provide sufficient social information to satisfy these needs, the study demonstrate the need to integrate the responsible social reporting into financial reporting. In order to support this reason, taking into account the data supplied by the entities listed on the Global Reporting Initiative regarding the corporate social responsibility. The results of the study show that social indicators can be disclosed in a monetary form which reinforces the need for their integration into financial reporting and the need to define a new concept: the social – financial responsible reporting.

A ''master key'' to chemical separation processes

International Nuclear Information System (INIS)

Madic, Ch.; Hill, C.

2002-01-01

One of the keys to sorting nuclear waste is extracting minor actinides - the most troublesome long-lived elements - from the flow of waste by separating them from lanthanides, which have very similar chemical properties to actinides, for possible transmutation into shorter-lived elements. Thanks to a European initiative coordinated by CEA, this key is now available: its name is Sanex. There now remains to develop tough, straightforward industrial processes to integrate it into a new nuclear waste management approach by 2005. Sanex joins the Diamex process, used for the combined separation of lanthanides and minor actinides from fission products. A third process, Sesame, designed to separate americium, completes the list of available separation processes. (authors)

KEY PERFORMANCE INDICATORS FOR HEALTHCARE RESEARCH ORGANIZATIONS BETWEEN 2011 AND 2015

OpenAIRE

ANISKEVICH A.S.; HALFIN R.A.

2017-01-01

In this work we identify 16 key indicators to evaluate the performance of healthcare research organizations. These indicators comprehensively characterize such aspects of performance as research output and relevance, human resource development, integration into the international scientific community, distribution of scientific knowledge, promotion of the prestige of science, and resource provision. Below, we review the existing classification of medical research institutions and their key fea...

Target and Tissue Selectivity Prediction by Integrated Mechanistic Pharmacokinetic-Target Binding and Quantitative Structure Activity Modeling.

Science.gov (United States)

Vlot, Anna H C; de Witte, Wilhelmus E A; Danhof, Meindert; van der Graaf, Piet H; van Westen, Gerard J P; de Lange, Elizabeth C M

2017-12-04

Selectivity is an important attribute of effective and safe drugs, and prediction of in vivo target and tissue selectivity would likely improve drug development success rates. However, a lack of understanding of the underlying (pharmacological) mechanisms and availability of directly applicable predictive methods complicates the prediction of selectivity. We explore the value of combining physiologically based pharmacokinetic (PBPK) modeling with quantitative structure-activity relationship (QSAR) modeling to predict the influence of the target dissociation constant (K D ) and the target dissociation rate constant on target and tissue selectivity. The K D values of CB1 ligands in the ChEMBL database are predicted by QSAR random forest (RF) modeling for the CB1 receptor and known off-targets (TRPV1, mGlu5, 5-HT1a). Of these CB1 ligands, rimonabant, CP-55940, and Δ 8 -tetrahydrocanabinol, one of the active ingredients of cannabis, were selected for simulations of target occupancy for CB1, TRPV1, mGlu5, and 5-HT1a in three brain regions, to illustrate the principles of the combined PBPK-QSAR modeling. Our combined PBPK and target binding modeling demonstrated that the optimal values of the K D and k off for target and tissue selectivity were dependent on target concentration and tissue distribution kinetics. Interestingly, if the target concentration is high and the perfusion of the target site is low, the optimal K D value is often not the lowest K D value, suggesting that optimization towards high drug-target affinity can decrease the benefit-risk ratio. The presented integrative structure-pharmacokinetic-pharmacodynamic modeling provides an improved understanding of tissue and target selectivity.

Public-key Encryption with Registered Keyword Search

NARCIS (Netherlands)

Tang, Qiang; Chen, Liqun

Public-key Encryption with Keyword Search (PEKS) enables a server to test whether a tag from a sender and a trapdoor from a receiver contain the same keyword. In this paper, we highlight some potential security concern, i.e. a curious server is able to answer whether any selected keyword is

Financial Development and Poverty Reduction Nexus: A Co-Integration and Causality Analysis in Selected Arabic Countries

Directory of Open Access Journals (Sweden)

Ayad Hicham

2017-06-01

Full Text Available This paper attempts the dynamic causal relationship between poverty reduction measured as consumption per capita and financial development measured as Kaopen and Milesi-Ferreti proxies, trade openness measured measured by the sum of total exports and total imports as a percentage of GDP at 2005 constant prices and economic growth as measured by GDP per capita for 14 selected Arabic countries within the panel co-integration techniques and TYDL Granger causality approach (1996, the results show that the poor people in Arabic countries (the selected countries did not benefit from liberalization systems and economic growth for the period because both of finance-led poverty and trade-led poverty seem to be rejected. The study, therefore, recommends that policy makers should stop the financial braking and adopt new financial policies that allow reducing poverty rates.

Neural Circuit to Integrate Opposing Motions in the Visual Field.

Science.gov (United States)

Mauss, Alex S; Pankova, Katarina; Arenz, Alexander; Nern, Aljoscha; Rubin, Gerald M; Borst, Alexander

2015-07-16

When navigating in their environment, animals use visual motion cues as feedback signals that are elicited by their own motion. Such signals are provided by wide-field neurons sampling motion directions at multiple image points as the animal maneuvers. Each one of these neurons responds selectively to a specific optic flow-field representing the spatial distribution of motion vectors on the retina. Here, we describe the discovery of a group of local, inhibitory interneurons in the fruit fly Drosophila key for filtering these cues. Using anatomy, molecular characterization, activity manipulation, and physiological recordings, we demonstrate that these interneurons convey direction-selective inhibition to wide-field neurons with opposite preferred direction and provide evidence for how their connectivity enables the computation required for integrating opposing motions. Our results indicate that, rather than sharpening directional selectivity per se, these circuit elements reduce noise by eliminating non-specific responses to complex visual information. Copyright © 2015 Elsevier Inc. All rights reserved.

Application of GRA for Sustainable Material Selection and Evaluation Using LCA

Science.gov (United States)

Jayakrishna, Kandasamy; Vinodh, Sekar; Sakthi Sanghvi, Vijayaselvan; Deepika, Chinadurai

2016-07-01

Material selection is identified as a successful key parameter in establishing any product to be sustainable, considering its end of life (EoL) characteristics. An accurate understanding of expected service conditions and environmental considerations are crucial in the selection of material plays a vital role with overwhelming customer expectations and stringent laws. Therefore, this article presents an integrated approach for sustainable material selection using grey relational analysis (GRA) considering the EoL disposal strategies with respect to an automotive product. GRA, an impact evaluation model measures the degree of similarity between the comparability (choice of material) sequence and reference (EoL strategies) sequence based on the relational grade. The ranking result shows that the outranking relationships in the order, ABS-REC > PP-INC > AL-REM > PP-LND > ABS-LND > ABS-INC > PU-LND > AL-REC > AL-LND > PU-INC > AL-INC. The best sustainable material selected was ABS and recycling was selected as the best EoL strategy with the grey relational value of 2.43856. The best material selected by this approach, ABS was evaluated for its viability using life cycle assessment and the estimated impacts also proved the practicability of the selected material highlighting the focus on dehumidification step in the manufacturing of the case product using this developed multi-criteria approach.

Integrating new practices: a qualitative study of how hospital innovations become routine.

Science.gov (United States)

Brewster, Amanda L; Curry, Leslie A; Cherlin, Emily J; Talbert-Slagle, Kristina; Horwitz, Leora I; Bradley, Elizabeth H

2015-12-05

Hospital quality improvement efforts absorb substantial time and resources, but many innovations fail to integrate into organizational routines, undermining the potential to sustain the new practices. Despite a well-developed literature on the initial implementation of new practices, we have limited knowledge about the mechanisms by which integration occurs. We conducted a qualitative study using a purposive sample of hospitals that participated in the State Action on Avoidable Rehospitalizations (STAAR) initiative, a collaborative to reduce hospital readmissions that encouraged members to adopt new practices. We selected hospitals where risk-standardized readmission rates (RSRR) had improved (n = 7) or deteriorated (n = 3) over the course of the first 2 years of the STAAR initiative (2010-2011 to 2011-2012) and interviewed a range of staff at each site (90 total). We recruited hospitals until reaching theoretical saturation. The constant comparative method was used to conduct coding and identification of key themes. When innovations were successfully integrated, participants consistently reported that a small number of key staff held the innovation in place for as long as a year while more permanent integrating mechanisms began to work. Depending on characteristics of the innovation, one of three categories of integrating mechanisms eventually took over the role of holding new practices in place. Innovations that proved intrinsically rewarding to the staff, by making their jobs easier or more gratifying, became integrated through shifts in attitudes and norms over time. Innovations for which the staff did not perceive benefits to themselves were integrated through revised performance standards if the innovation involved complex tasks and through automation if the innovation involved simple tasks. Hospitals have an opportunity to promote the integration of new practices by planning for the extended effort required to hold a new practice in place while

Integrated services

International Nuclear Information System (INIS)

Chafcouloff, S.; Michel, G.; Trice, M.; Clark, G.; Cosad, C.; Forbes, K.

1995-01-01

Integrated services is the name given to several services grouped together under a single contract. Four key factors determine the success of integrated services projects: teamwork, common objectives, technology, and shared benefits. For oil companies, integration means smoother, more efficient operations by bringing service companies on board as part of the team. For the service industry, it means a radical change in the way business is conducted, taking on more responsibility in return for greater incentives. This article reviews the need for change and the approach Schlumberger has adopted to meet this challenge. 20 figs., 20 refs

Integrated services

Energy Technology Data Exchange (ETDEWEB)

Chafcouloff, S.; Michel, G.; Trice, M. [Schlumberger Integrated Project Management Group, Montrouge (France); Clark, G. [Schlumberger Testing Services, Aberdeen (United Kingdom); Cosad, C.; Forbes, K. [Schlumberger Integrated Project Management Group, Aberdeen (United Kingdom)

1995-12-31

Integrated services is the name given to several services grouped together under a single contract. Four key factors determine the success of integrated services projects: teamwork, common objectives, technology, and shared benefits. For oil companies, integration means smoother, more efficient operations by bringing service companies on board as part of the team. For the service industry, it means a radical change in the way business is conducted, taking on more responsibility in return for greater incentives. This article reviews the need for change and the approach Schlumberger has adopted to meet this challenge. 20 figs., 20 refs

Clonal selection versus clonal cooperation: the integrated perception of immune objects [version 1; referees: 2 approved

Directory of Open Access Journals (Sweden)

Serge Nataf

2016-09-01

Full Text Available Analogies between the immune and nervous systems were first envisioned by the immunologist Niels Jerne who introduced the concepts of antigen "recognition" and immune "memory". However, since then, it appears that only the cognitive immunology paradigm proposed by Irun Cohen, attempted to further theorize the immune system functions through the prism of neurosciences. The present paper is aimed at revisiting this analogy-based reasoning. In particular, a parallel is drawn between the brain pathways of visual perception and the processes allowing the global perception of an "immune object". Thus, in the visual system, distinct features of a visual object (shape, color, motion are perceived separately by distinct neuronal populations during a primary perception task. The output signals generated during this first step instruct then an integrated perception task performed by other neuronal networks. Such a higher order perception step is by essence a cooperative task that is mandatory for the global perception of visual objects. Based on a re-interpretation of recent experimental data, it is suggested that similar general principles drive the integrated perception of immune objects in secondary lymphoid organs (SLOs. In this scheme, the four main categories of signals characterizing an immune object (antigenic, contextual, temporal and localization signals are first perceived separately by distinct networks of immunocompetent cells.  Then, in a multitude of SLO niches, the output signals generated during this primary perception step are integrated by TH-cells at the single cell level. This process eventually generates a multitude of T-cell and B-cell clones that perform, at the scale of SLOs, an integrated perception of immune objects. Overall, this new framework proposes that integrated immune perception and, consequently, integrated immune responses, rely essentially on clonal cooperation rather than clonal selection.

Building-Integrated Solar Energy Devices based on Wavelength Selective Films

Science.gov (United States)

Ulavi, Tejas

A potentially attractive option for building integrated solar is to employ hybrid solar collectors which serve dual purposes, combining solar thermal technology with either thin film photovoltaics or daylighting. In this study, two hybrid concepts, a hybrid photovoltaic/thermal (PV/T) collector and a hybrid 'solar window', are presented and analyzed to evaluate technical performance. In both concepts, a wavelength selective film is coupled with a compound parabolic concentrator (CPC) to reflect and concentrate the infrared portion of the solar spectrum onto a tubular absorber. The visible portion of the spectrum is transmitted through the concentrator to either a thin film Cadmium Telluride (CdTe) solar panel for electricity generation or into the interior space for daylighting. Special attention is given to the design of the hybrid devices for aesthetic building integration. An adaptive concentrator design based on asymmetrical truncation of CPCs is presented for the hybrid solar window concept. The energetic and spectral split between the solar thermal module and the PV or daylighting module are functions of the optical properties of the wavelength selective film and the concentrator geometry, and are determined using a Monte Carlo Ray-Tracing (MCRT) model. Results obtained from the MCRT can be used in conjugation with meteorological data for specific applications to study the impact of CPC design parameters including the half-acceptance angle thetac, absorber diameter D and truncation on the annual thermal and PV/daylighting efficiencies. The hybrid PV/T system is analyzed for a rooftop application in Phoenix, AZ. Compared to a system of the same area with independent solar thermal and PV modules, the hybrid PV/T provides 20% more energy, annually. However, the increase in total delivered energy is due solely to the addition of the thermal module and is achieved at an expense of a decrease in the annual electrical efficiency from 8.8% to 5.8% due to shading by

An in-building network based on community access television integration with quadrature phase-shift keying orthogonal frequency-division multiplexing

International Nuclear Information System (INIS)

Chen, Chia-Yi; Lin, Ying-Pyng; Lu, Hai-Han; Wu, Po-Yi; Lin, Huang-Chang; Wu, Hsiao-Wen

2012-01-01

An in-building network based on cable television (CATV) integration with quadrature phase-shift keying (QPSK) orthogonal frequency-division multiplexing (OFDM) transport over a combination of single-mode fibers (SMF) and perfluorinated graded-index plastic optical fibers (GI-POF) is proposed and experimentally demonstrated. In this system, a 1558.5 nm optical signal is directly transmitted along two fiber spans (20 km SMF + 25 m GI-POF). An optimum guard band is carefully established to ensure that no very substantial signal interference is induced between the CATV and QPSK OFDM bands. Error free transmission with sufficiently low bit error rate values was achieved for 1.25 Gbps/771.5 MHz QPSK OFDM signals; also, acceptable carrier-to-noise ratio, composite second-order, and composite triple-beat performances were obtained for CATV signals. This proposed network is significant because it is economical and convenient to install. (paper)

Integrative structure modeling with the Integrative Modeling Platform.

Science.gov (United States)

Webb, Benjamin; Viswanath, Shruthi; Bonomi, Massimiliano; Pellarin, Riccardo; Greenberg, Charles H; Saltzberg, Daniel; Sali, Andrej

2018-01-01

Building models of a biological system that are consistent with the myriad data available is one of the key challenges in biology. Modeling the structure and dynamics of macromolecular assemblies, for example, can give insights into how biological systems work, evolved, might be controlled, and even designed. Integrative structure modeling casts the building of structural models as a computational optimization problem, for which information about the assembly is encoded into a scoring function that evaluates candidate models. Here, we describe our open source software suite for integrative structure modeling, Integrative Modeling Platform (https://integrativemodeling.org), and demonstrate its use. © 2017 The Protein Society.

國民核心素養與高中課程發展The Development of Integration of Key Competence into the Senior High School Curriculum

Directory of Open Access Journals (Sweden)

林永豐 Yung-Feng Lin

2013-03-01

Full Text Available 本研究旨在說明如何依據後期中等教育階段之核心素養，融入普通高中各學科 課程綱要，進而建構各學科課程之核心素養指標，以達成「K-12年級一貫課程綱要」的「核心素養」之「垂直銜接」與「水平統整」，並做為進一步擬訂「十二年一貫課程體系指引」之基礎。本研究透過文件分析與德懷術探討現行普通高中課程各學科與核心素養之對應關係，以瞭解如何將核心素養融入各學科課程中，達至學科課程與核心素養之課程統整。本研究結論有三，包括：一、普通高中各學科與核心素養的相關性高，應強化核心素養的培養與精進；二、普通高中各學科課綱中所列之核心能力與國民核心素養九個項目有對應之處，亦有不足之處；三、普通高中教育向來重視學科知能的教學，應調整為內容與能力兼具的課程取向。本研究建議：一、依據核心素養的理念，建議重新檢討並修正各科之課程目標與核心能力；二、宜進一步針對尚未分析之六科進行核心素養之分析；三、納入更多各學科專家與實務教師，討論並修正各科之核心素養等。This paper aims to elaborate how can the key competences for upper secondary education stage be integrated into the curriculum of senior high schools. Moreover, it is hoped that indicators of key competences in different subjects can be built up so that key competences for the K-12 grades curriculum could be established being both vertically coherent in different grades and horizontally integrated with other academic subjects. This study adopt document analysis and the Delphi technique as main research methods with particular focus on the relationship between key competences and main subjects in the senior high school curriculum. Three main conclusions are summarized as follows. First, there is a strong relationship between the key

The Integration of Corporate Non-Market and Market Strategies

DEFF Research Database (Denmark)

Xie, Peihong; Li, Xin; Xie, Xuemei

2014-01-01

Purpose: This paper aims to systematically examine the key notion of integration of non-market and market strategies in the increasingly popular study of corporate non-market strategies. Design/methodology/approach: This paper is based on a brief literature review of the non-market strategy (NMS...... explore how to seamlessly coordinate non-market and market strategies in order to gain maximal synergies. Originality/value: This paper is the first to examine the key notion of integration in a systematic manner. It is the first to propose a three-question solution to systematic understanding......) research that shows the existing literature does not offer a clear and systematic account of the key notion of integration. It suggests any systematic account of integration should address at least three interrelated questions, i.e. why, what and how to integrate non-market and market strategies? Findings...

Minimizing Project Cost by Integrating Subcontractor Selection Decisions with Scheduling

Science.gov (United States)

Biruk, Sławomir; Jaśkowski, Piotr; Czarnigowska, Agata

2017-10-01

Subcontracting has been a worldwide practice in the construction industry. It enables the construction enterprises to focus on their core competences and, at the same time, it makes complex project possible to be delivered. Since general contractors bear full responsibility for the works carried out by their subcontractors, it is their task and their risk to select a right subcontractor for a particular work. Although subcontractor management has been admitted to significantly affect the construction project’s performance, current practices and past research deal with subcontractor management and scheduling separately. The proposed model aims to support subcontracting decisions by integrating subcontractor selection with scheduling to enable the general contractor to select the optimal combination of subcontractors and own crews for all work packages of the project. The model allows for the interactions between the subcontractors and their impacts on the overall project performance in terms of cost and, indirectly, time and quality. The model is intended to be used at the general contractor’s bid preparation stage. The authors claim that the subcontracting decisions should be taken in a two-stage process. The first stage is a prequalification - provision of a short list of capable and reliable subcontractors; this stage is not the focus of the paper. The resulting pool of available resources is divided into two subsets: subcontractors, and general contractor’s in-house crews. Once it has been defined, the next stage is to assign them to the work packages that, bound by fixed precedence constraints, form the project’s network diagram. Each package is possible to be delivered by the general contractor’s crew or some of the potential subcontractors, at a specific time and cost. Particular crews and subcontractors can be contracted more than one package, but not at the same time. Other constraints include the predefined project completion date (the project is

Selective mutism: a review and integration of the last 15 years.

Science.gov (United States)

Viana, Andres G; Beidel, Deborah C; Rabian, Brian

2009-02-01

Selective mutism (SM) is a rare childhood disorder characterized by a lack of speech in one or more settings in which speaking is socially expected. A comprehensive and uniform theory about the etiology, assessment, and treatment of SM does not exist. Historically, varying definitions and criteria have been applied to children with SM, therefore making comparisons between studies somewhat difficult. Accumulating findings on the phenomenology of SM point to a complex and multidetermined etiology. Developmental psychopathology represents a useful heuristic for conceptualization of SM and serves as an integrative framework for organizing the sometimes disparate findings that permeate the SM literature. The purpose of this review is to summarize the literature on SM, including phenomenology, assessment, and treatment, with the main goals of clarifying its clinical presentation, offering a theoretical understanding of SM from a developmental psychopathology perspective, and highlighting both research and practice gaps that may exist. Recommendations for future research are made with the goal of expanding the current knowledge base on the etiology of SM.

Four integration patterns

DEFF Research Database (Denmark)

Bygstad, Bendik; Nielsen, Peter Axel; Munkvold, Bjørn Erik

2010-01-01

This paper aims to contribute to a theory of integration within the field of IS project management. Integration is a key IS project management issue when new systems are developed and implemented into an increasingly integrated information infrastructure in corporate and governmental organizations....... Expanding the perspective of traditional project management research, we draw extensively on central insights from IS research. Building on socio-technical IS research and Software Engineering research we suggest four generic patterns of integration: Big Bang, Stakeholder Integration, Technical Integration...... and Socio-Technical Integration. We analyze and describe the advantages and disadvantages of each pattern. The four patterns are ideal types. To explore the forces and challenges in these patterns three longitudinal case studies were conducted. In particular we investigate the management challenges for each...

Integrated Management of Migration, Employment, Fiscal Policy and Public Debt

Directory of Open Access Journals (Sweden)

Aleksandras Vytautas Rutkauskas

2013-09-01

Full Text Available The main idea of the paper states that national migration indicators are closely related with employment opportunities in that country. In addition, the management quality of migration and employment processes is an indicator of the national socio-economic policy competency, while management of these processes is the main purpose of intelligent adjustment of the national fiscal policy and government debt management. The author of the paper selected the formation of the system of quantitative indicators as the main objective of the paper. The system should allow employing government debt possibilities for the selection of proper fiscal policy in order to prevent the transformation of unemployment into the key reason of uncontrolled national inflation. This would be done by revealing the possibilities of fiscal policy to impact on the level and structure of unemployment. Recent globalisation processes and integration possibilities bring a lot of uncertainty to predetermined viability of theoretical assumptions as well as the adequacy of the applied quantitative methods. The paper uses the possibilities of stochastic optimisation and stochastically informed expertise pursuing the possibilities of integrated management of employment, migration processes, fiscal policy and government debt provisions.

Discrete systems and integrability

CERN Document Server

Hietarinta, J; Nijhoff, F W

2016-01-01

This first introductory text to discrete integrable systems introduces key notions of integrability from the vantage point of discrete systems, also making connections with the continuous theory where relevant. While treating the material at an elementary level, the book also highlights many recent developments. Topics include: Darboux and Bäcklund transformations; difference equations and special functions; multidimensional consistency of integrable lattice equations; associated linear problems (Lax pairs); connections with Padé approximants and convergence algorithms; singularities and geometry; Hirota's bilinear formalism for lattices; intriguing properties of discrete Painlevé equations; and the novel theory of Lagrangian multiforms. The book builds the material in an organic way, emphasizing interconnections between the various approaches, while the exposition is mostly done through explicit computations on key examples. Written by respected experts in the field, the numerous exercises and the thoroug...

VLSI IMPLEMENTATION OF NOVEL ROUND KEYS GENERATION SCHEME FOR CRYPTOGRAPHY APPLICATIONS BY ERROR CONTROL ALGORITHM

Directory of Open Access Journals (Sweden)

B. SENTHILKUMAR

2015-05-01

Full Text Available A novel implementation of code based cryptography (Cryptocoding technique for multi-layer key distribution scheme is presented. VLSI chip is designed for storing information on generation of round keys. New algorithm is developed for reduced key size with optimal performance. Error Control Algorithm is employed for both generation of round keys and diffusion of non-linearity among them. Two new functions for bit inversion and its reversal are developed for cryptocoding. Probability of retrieving original key from any other round keys is reduced by diffusing nonlinear selective bit inversions on round keys. Randomized selective bit inversions are done on equal length of key bits by Round Constant Feedback Shift Register within the error correction limits of chosen code. Complexity of retrieving the original key from any other round keys is increased by optimal hardware usage. Proposed design is simulated and synthesized using VHDL coding for Spartan3E FPGA and results are shown. Comparative analysis is done between 128 bit Advanced Encryption Standard round keys and proposed round keys for showing security strength of proposed algorithm. This paper concludes that chip based multi-layer key distribution of proposed algorithm is an enhanced solution to the existing threats on cryptography algorithms.

Integrating resource selection information with spatial capture--recapture

Science.gov (United States)

Royle, J. Andrew; Chandler, Richard B.; Sun, Catherine C.; Fuller, Angela K.

2013-01-01

1. Understanding space usage and resource selection is a primary focus of many studies of animal populations. Usually, such studies are based on location data obtained from telemetry, and resource selection functions (RSFs) are used for inference. Another important focus of wildlife research is estimation and modeling population size and density. Recently developed spatial capture–recapture (SCR) models accomplish this objective using individual encounter history data with auxiliary spatial information on location of capture. SCR models include encounter probability functions that are intuitively related to RSFs, but to date, no one has extended SCR models to allow for explicit inference about space usage and resource selection.

Key Concept Identification: A Comprehensive Analysis of Frequency and Topical Graph-Based Approaches

Directory of Open Access Journals (Sweden)

Muhammad Aman

2018-05-01

Full Text Available Automatic key concept extraction from text is the main challenging task in information extraction, information retrieval and digital libraries, ontology learning, and text analysis. The statistical frequency and topical graph-based ranking are the two kinds of potentially powerful and leading unsupervised approaches in this area, devised to address the problem. To utilize the potential of these approaches and improve key concept identification, a comprehensive performance analysis of these approaches on datasets from different domains is needed. The objective of the study presented in this paper is to perform a comprehensive empirical analysis of selected frequency and topical graph-based algorithms for key concept extraction on three different datasets, to identify the major sources of error in these approaches. For experimental analysis, we have selected TF-IDF, KP-Miner and TopicRank. Three major sources of error, i.e., frequency errors, syntactical errors and semantical errors, and the factors that contribute to these errors are identified. Analysis of the results reveals that performance of the selected approaches is significantly degraded by these errors. These findings can help us develop an intelligent solution for key concept extraction in the future.

Corporate Author Entry Records Retrieved by Use of Derived Truncated Search Keys

Directory of Open Access Journals (Sweden)

Alan L. Landgraf

1973-09-01

Full Text Available An experiment was conducted to design a corporate author index to a large bibliographic file. The nature of corporate entries necessitates a different search key construction from that of personal names or titles. Derivation of a search key to select distinct corporate entry records is discussed.

Network Information Management: The Key To Providing High WAN Availability.

Science.gov (United States)

Tysdal, Craig

1996-01-01

Discusses problems associated with increasing corporate network complexity as a result of the proliferation of client/server applications at remote locations, and suggests the key to providing high WAN (wide area network) availability is relational databases used in an integrated management approach. (LRW)

Retroviral integration: Site matters

Science.gov (United States)

Demeulemeester, Jonas; De Rijck, Jan

2015-01-01

Here, we review genomic target site selection during retroviral integration as a multistep process in which specific biases are introduced at each level. The first asymmetries are introduced when the virus takes a specific route into the nucleus. Next, by co‐opting distinct host cofactors, the integration machinery is guided to particular chromatin contexts. As the viral integrase captures a local target nucleosome, specific contacts introduce fine‐grained biases in the integration site distribution. In vivo, the established population of proviruses is subject to both positive and negative selection, thereby continuously reshaping the integration site distribution. By affecting stochastic proviral expression as well as the mutagenic potential of the virus, integration site choice may be an inherent part of the evolutionary strategies used by different retroviruses to maximise reproductive success. PMID:26293289

A novel integrated assessment methodology of urban water reuse.

Science.gov (United States)

Listowski, A; Ngo, H H; Guo, W S; Vigneswaran, S

2011-01-01

Wastewater is no longer considered a waste product and water reuse needs to play a stronger part in securing urban water supply. Although treatment technologies for water reclamation have significantly improved the question that deserves further analysis is, how selection of a particular wastewater treatment technology relates to performance and sustainability? The proposed assessment model integrates; (i) technology, characterised by selected quantity and quality performance parameters; (ii) productivity, efficiency and reliability criteria; (iii) quantitative performance indicators; (iv) development of evaluation model. The challenges related to hierarchy and selections of performance indicators have been resolved through the case study analysis. The goal of this study is to validate a new assessment methodology in relation to performance of the microfiltration (MF) technology, a key element of the treatment process. Specific performance data and measurements were obtained at specific Control and Data Acquisition Points (CP) to satisfy the input-output inventory in relation to water resources, products, material flows, energy requirements, chemicals use, etc. Performance assessment process contains analysis and necessary linking across important parametric functions leading to reliable outcomes and results.

The 5C model: A new approach to asset integrity management

International Nuclear Information System (INIS)

Rahim, Yousif; Refsdal, Ingbjorn; Kenett, Ron S.

2010-01-01

As organizations grow more complex in operation and more global in scope, assets and technical integrity become key success factors. A company's asset integrity business process needs to be mapped in order to 1) provide a proper overview of operation and business processes, 2) identify all critical interfaces and 3) ensure that all gaps and overlaps in processes are eliminated. Achieving asset integrity requires companies to sustain their activities and identify the hazards, weaknesses and objectives of their strategic assets. Technical integrity emphasizes a complete overview of technical conditions and related information, and the ability of the companies to document the technical state of its assets. It is based on an integrated view of the current state of operations, and the identification of all critical interfaces, in order to ensure that all gaps and unnecessary overlaps in processes are eliminated. Companies look increasingly at their asset integrity management system as a means to extend the life of their assets, beyond the original design conditions and production capacity. Establishing an asset integrity management system requires the documentation of the company's technical integrity management, a strategy and the processes for carrying it out, identifying gaps; selecting corrective interventions and conducting follow up actions. The paper discusses various aspects of asset integrity management, including its planning and implementation. We begin with an introduction to asset technical integrity, provide some theoretical backgrounds, present a model we call 5C and conclude with a summary and discussion.

Integrated primary health care in Greece, a missing issue in the current health policy agenda: a systematic review

Directory of Open Access Journals (Sweden)

Christos Lionis

2009-07-01

Full Text Available Background: Over the past years, Greece has undergone several endeavors aimed at modernizing and improving national health care services with a focus on PHC. However, the extent to which integrated primary health care has been achieved is still questioned. Purpose: This paper explores the extent to which integrated primary health care (PHC is an issue in the current agenda of policy makers in Greece, reporting constraints and opportunities and highlighting the need for a policy perspective in developing integrated PHC in this Southern European country. Methods: A systematic review in PubMed/Medline and SCOPUS, along with a hand search in selected Greek biomedical journals was undertaken to identify key papers, reports, editorials or opinion letters relevant to integrated health care. Results: Our systematic review identified 198 papers and 161 out of them were derived from electronic search. Fifty-three papers in total served the scope of this review and are shortly reported. A key finding is that the long-standing dominance of medical perspectives in Greek health policy has been paving the way towards vertical integration, pushing aside any discussions about horizontal or comprehensive integration of care. Conclusion: Establishment of integrated PHC in Greece is still at its infancy, requiring major restructuring of the current national health system, as well as organizational culture changes. Moving towards a new policy-based model would bring this missing issue on the discussion table, facilitating further development.

Using omics and integrated multi-omics approaches to guide probiotic selection to mitigate chytridiomycosis and other emerging infectious diseases

Directory of Open Access Journals (Sweden)

Eria Alaide Rebollar

2016-02-01

Full Text Available Emerging infectious diseases in wildlife are responsible for massive population declines. In amphibians, chytridiomycosis caused by Batrachochytrium dendrobatidis, Bd, has severely affected many amphibian populations and species around the world. One promising management strategy is probiotic bioaugmentation of antifungal bacteria on amphibian skin. In vivo experimental trials using bioaugmentation strategies have had mixed results, and therefore a more informed strategy is needed to select successful probiotic candidates. Metagenomic, transcriptomic, and metabolomic methods, colloquially called omics, are approaches that can better inform probiotic selection and optimize selection protocols. The integration of multiple omic data using bioinformatic and statistical tools and in silico models that link bacterial community structure with bacterial defensive function can allow the identification of species involved in pathogen inhibition. We recommend using 16S rRNA gene amplicon sequencing and methods such as indicator species analysis, the K-S Measure, and co-occurrence networks to identify bacteria that are associated with pathogen resistance in field surveys and experimental trials. In addition to 16S amplicon sequencing, we recommend approaches that give insight into symbiont function such as shotgun metagenomics, metatranscriptomics or metabolomics to maximize the probability of finding effective probiotic candidates, which can then be isolated in culture and tested in persistence and clinical trials. An effective mitigation strategy to ameliorate chytridiomycosis and other emerging infectious diseases is necessary; the advancement of omic methods and the integration of multiple omic data provide a promising avenue toward conservation of imperiled species.

Integral fast reactor concept

International Nuclear Information System (INIS)

Chang, Y.I.; Marchaterre, J.F.; Sevy, R.H.

1984-01-01

Key features of the IFR consist of a pool-type plant arrangement, a metal fuel-based core design, and an integral fuel cycle with colocated fuel cycle facility. Both the basic concept and the technology base have been demonstrated through actual integral cycle operation in EBR-II. This paper discusses the inherent safety characteristics of the IFR concept

In vitro application of integrated selection index for screening drought tolerant genotypes in common wheat

Directory of Open Access Journals (Sweden)

Ezatollah FARSHADFAR

2016-10-01

Full Text Available This experiment was conducted on 20 wheat genotypes during 2010-2011 growing season at the Razi University, Kermanshah, Iran. A completely randomized design with six replications was used for callus induction and a 20 × 2 factorial experiment with three replications was used for response of genotypes to in vitro drought stress. ANOVA exhibited highly significant differences among the genotypes for callus growth rate, relative fresh mass growth, relative growth rate, callus water content, percent of callus chlorosis and proline content under stress condition (15 % PEG. PCA showed that the integrated selection index was correlated with callus growth index, relative fresh mass growth, relative growth rate and proline content indicating that these screening techniques can be useful for selecting drought tolerant genotypes. Screening drought tolerant genotypes and in vitro indicators of drought tolerance using mean rank, standard deviation of ranks and biplot analysis, discriminated genotypes 2, 18 and 10 as the most drought tolerant. Therefore they are recommended to be used as parents for genetic analysis, gene mapping and improvement of drought tolerance.

The INTEGRAL Core Observing Programme

DEFF Research Database (Denmark)

Winkler, C.; Gehrels, N.; Lund, Niels

1999-01-01

The Core Programme of the INTEGRAL mission is defined as the portion of the scientific programme covering the guaranteed time observations for the INTEGRAL Science Working Team. This paper describes the current status of the Core Programme preparations and summarizes the key elements...... of the observing programme....

Feature selection for high-dimensional integrated data

KAUST Repository

Zheng, Charles

2012-04-26

Motivated by the problem of identifying correlations between genes or features of two related biological systems, we propose a model of feature selection in which only a subset of the predictors Xt are dependent on the multidimensional variate Y, and the remainder of the predictors constitute a “noise set” Xu independent of Y. Using Monte Carlo simulations, we investigated the relative performance of two methods: thresholding and singular-value decomposition, in combination with stochastic optimization to determine “empirical bounds” on the small-sample accuracy of an asymptotic approximation. We demonstrate utility of the thresholding and SVD feature selection methods to with respect to a recent infant intestinal gene expression and metagenomics dataset.

Feature selection for high-dimensional integrated data

KAUST Repository

Zheng, Charles; Schwartz, Scott; Chapkin, Robert S.; Carroll, Raymond J.; Ivanov, Ivan

2012-01-01

Motivated by the problem of identifying correlations between genes or features of two related biological systems, we propose a model of feature selection in which only a subset of the predictors Xt are dependent on the multidimensional variate Y, and the remainder of the predictors constitute a “noise set” Xu independent of Y. Using Monte Carlo simulations, we investigated the relative performance of two methods: thresholding and singular-value decomposition, in combination with stochastic optimization to determine “empirical bounds” on the small-sample accuracy of an asymptotic approximation. We demonstrate utility of the thresholding and SVD feature selection methods to with respect to a recent infant intestinal gene expression and metagenomics dataset.

Cryptographic Key Management and Critical Risk Assessment

Energy Technology Data Exchange (ETDEWEB)

Abercrombie, Robert K [ORNL

2014-05-01

operation. To further address probabilities of threats, information security analysis can be performed using game theory implemented in dynamic Agent Based Game Theoretic (ABGT) simulations. Such simulations can be verified with the results from game theory analysis and further used to explore larger scale, real world scenarios involving multiple attackers, defenders, and information assets. The strategy for the game was developed by analyzing five electric sector representative failure scenarios contained in the AMI functional domain from NESCOR WG1. From these five selected scenarios, we characterized them into three specific threat categories affecting confidentiality, integrity and availability (CIA). The analysis using our ABGT simulation demonstrated how to model the AMI functional domain using a set of rationalized game theoretic rules decomposed from the failure scenarios in terms of how those scenarios might impact the AMI network with respect to CIA.

Conditional maximum-entropy method for selecting prior distributions in Bayesian statistics

Science.gov (United States)

Abe, Sumiyoshi

2014-11-01

The conditional maximum-entropy method (abbreviated here as C-MaxEnt) is formulated for selecting prior probability distributions in Bayesian statistics for parameter estimation. This method is inspired by a statistical-mechanical approach to systems governed by dynamics with largely separated time scales and is based on three key concepts: conjugate pairs of variables, dimensionless integration measures with coarse-graining factors and partial maximization of the joint entropy. The method enables one to calculate a prior purely from a likelihood in a simple way. It is shown, in particular, how it not only yields Jeffreys's rules but also reveals new structures hidden behind them.

An Empirical Analysis of Post-Merger Organizational Integration

DEFF Research Database (Denmark)

Smeets, Valerie Anne Rolande; Ierulli, Kathryn; Gibbs, Michael

2016-01-01

existing establishments. Worker turnover is high after merger, but new hiring yields stable total employment. Target employees have higher turnover and reassignment, particularly if the target firm is small relative to the acquiring firm. These findings may suggest integration is costly, but can......We study post-merger organizational integration using linked employer-employee data. Integration is implemented by reassigning a small number of high skilled workers, especially in R&D and management. Workforce mixing is concentrated to establishments set up after merger rather than to previously...... be achieved by focusing on key employees. Alternatively, reassigning a few key employees is sufficient for achieving integration....

Building a progressive vertical integration

International Nuclear Information System (INIS)

Charette, D.

2008-01-01

AAER Inc. is a Quebec-based company that manufactures turbines using proven European designs. This presentation discussed the company's business model. The company places an emphasis on identifying strategic and key components currently available for its turbines. Market analyses are performed in order to determine ideal suppliers and define business strategies and needs. The company invests in long-term relationships with its suppliers. Business partners for AAER are of a similar size and have a mutual understanding and respect for the company's business practices. Long-term agreements with suppliers are signed in order to ensure reliability and control over costs. Progressive vertical integration has been achieved by progressively manufacturing key components and integrating a North American supply chain. The company's secure supply chain and progressive vertical integration has significantly reduced financial costs and provided better quality control. It was concluded that vertical integration has also allowed AAER to provide better customer service and reduce transportation costs. tabs., figs

Screening key parameters related to passive system performance based on Analytic Hierarchy Process

International Nuclear Information System (INIS)

Ma, Guohang; Yu, Yu; Huang, Xiong; Peng, Yuan; Ma, Nan; Shan, Zuhua; Niu, Fenglei; Wang, Shengfei

2015-01-01

Highlights: • An improved AHP method is presented for screening key parameters used in passive system reliability analysis. • We take the special bottom parameters as criterion for calculation and the abrupt change of the results are verified. • Combination weights are also affected by uncertainty of input parameters. - Abstract: Passive safety system is widely used in the new generation nuclear power plant (NPP) designs such as AP1000 to improve the reactor safety benefitting from its simple construction and less request for human intervene. However, the functional failure induced by uncertainty in the system thermal–hydraulic (T–H) performance becomes one of the main contributors to system operational failure since the system operates based on natural circulation, which should be considered in the system reliability evaluation. In order to improve the calculation efficiency the key parameters which significantly affect the system T–H characteristics can be screened and then be analyzed in detail. The Analytical Hierarchy Process (AHP) is one of the efficient methods to analyze the influence of the parameters on a passive system based on the experts’ experience. The passive containment cooling system (PCCS) in AP1000 is one of the typical passive safety systems, nevertheless too many parameters need to be analyzed and the T–H model itself is more complicated, so the traditional AHP method should be mended to use for screening key parameters efficiently. In this paper, we adapt the improved method in hierarchy construction and experts’ opinions integration, some parameters at the bottom justly in the traditional hierarchy are studied as criterion layer in improved AHP, the rationality of the method and the effect of abrupt change with the data are verified. The passive containment cooling system (PCCS) in AP1000 is evaluated as an example, and four key parameters are selected from 49 inputs

Biased random key genetic algorithm with insertion and gender selection for capacitated vehicle routing problem with time windows

Science.gov (United States)

Rochman, Auliya Noor; Prasetyo, Hari; Nugroho, Munajat Tri

2017-06-01

Vehicle Routing Problem (VRP) often occurs when the manufacturers need to distribute their product to some customers/outlets. The distribution process is typically restricted by the capacity of the vehicle and the working hours at the distributor. This type of VRP is also known as Capacitated Vehicle Routing Problem with Time Windows (CVRPTW). A Biased Random Key Genetic Algorithm (BRKGA) was designed and coded in MATLAB to solve the CVRPTW case of soft drink distribution. The standard BRKGA was then modified by applying chromosome insertion into the initial population and defining chromosome gender for parent undergoing crossover operation. The performance of the established algorithms was then compared to a heuristic procedure for solving a soft drink distribution. Some findings are revealed (1) the total distribution cost of BRKGA with insertion (BRKGA-I) results in a cost saving of 39% compared to the total cost of heuristic method, (2) BRKGA with the gender selection (BRKGA-GS) could further improve the performance of the heuristic method. However, the BRKGA-GS tends to yield worse results compared to that obtained from the standard BRKGA.

The I.A.G./A.I.G. SEDIBUD (Sediment Budgets in Cold Environments) Program (2005 - 2017): Key activities and outcomes

Science.gov (United States)

Beylich, Achim A.

2017-04-01

out at 56 defined SEDIBUD key test sites (selected catchment systems) varies by scientific program, logistics and available resources, but typically represent interdisciplinary collaborations of geomorphologists, hydrologists, ecologists, permafrost scientists and glaciologists with different levels of detail. SEDIBUD has developed a key set of primary research data requirements intended to incorporate results from these varied projects and allow quantitative analysis across the program. Defined SEDIBUD key test sites provide field data on annual climatic conditions, total discharge and particulate and dissolved fluxes and yields as well as information on other relevant denudational Earth surface processes. A number of selected key test sites are providing high-resolution data on climatic conditions, runoff and solute and sedimentary fluxes and yields, which - in addition to the annual data - contribute to the SEDIBUD metadata database. To support these coordinated efforts, the SEDIFLUX manual and a set of framework papers and book chapters have been produced to establish the integrative approach and common methods and data standards. Comparable field-datasets from different SEDIBUD key test sites are analyzed and integrated to address key research questions of the SEDIBUD program as defined in the SEDIBUD working group objective. A key SEDIBUD synthesis book was published in 2016 by the group and a synthesis key paper is currently in preparation. Detailed information on all SEDIBUD activities, outcomes and published products is found at http://www.geomorph.org/sedibud-working-group/.

Design and cost estimate for the SRL integrated hot off gas facility using selective adsorption

International Nuclear Information System (INIS)

Pence, D.T.; Kirstein, B.E.

1981-07-01

Based on the results of an engineering-scale demonstration program, a design and cost estimate were performed for a 25-m 3 /h (15-ft 3 /min) capacity pilot plant demonstration system using selective adsorption technology for installation at the Integrated Hot Off Gas Facility at the Savannah River Plant. The design includes provisions for the destruction of NO/sub x/ and the concentration and removal of radioisotopes of ruthenium, iodine-129, tritiated water vapor, carbon-14 contaminated carbon dioxide, and krypton-85. The nobel gases are separated by the use of selective adsorption on mordenite-type zeolites. The theory of noble gas adsorption on zeolites is essentially the same as that for the adsorption of noble gases on activated charcoals. Considerable detail is provided regarding the application of the theory to adsorbent bed designs and operation. The design is based on a comprehensive material balance and appropriate heat transfer calculations. Details are provided on techniques and procedures used for heating, cooling, and desorbing the adsorbent columns. Analyses are also given regarding component and arrangement selection and includes discussions on alternative arrangements. The estimated equipment costs for the described treatment system is about $1,400,000. The cost estimate includes a detailed equipment list of all the major component items in the design. Related technical issues and estimated system performance are also discussed

Design and cost estimate for the SRL integrated hot off gas facility using selective adsorption

Energy Technology Data Exchange (ETDEWEB)

Pence, D T; Kirstein, B E

1981-07-01

Based on the results of an engineering-scale demonstration program, a design and cost estimate were performed for a 25-m/sup 3//h (15-ft/sup 3//min) capacity pilot plant demonstration system using selective adsorption technology for installation at the Integrated Hot Off Gas Facility at the Savannah River Plant. The design includes provisions for the destruction of NO/sub x/ and the concentration and removal of radioisotopes of ruthenium, iodine-129, tritiated water vapor, carbon-14 contaminated carbon dioxide, and krypton-85. The nobel gases are separated by the use of selective adsorption on mordenite-type zeolites. The theory of noble gas adsorption on zeolites is essentially the same as that for the adsorption of noble gases on activated charcoals. Considerable detail is provided regarding the application of the theory to adsorbent bed designs and operation. The design is based on a comprehensive material balance and appropriate heat transfer calculations. Details are provided on techniques and procedures used for heating, cooling, and desorbing the adsorbent columns. Analyses are also given regarding component and arrangement selection and includes discussions on alternative arrangements. The estimated equipment costs for the described treatment system is about $1,400,000. The cost estimate includes a detailed equipment list of all the major component items in the design. Related technical issues and estimated system performance are also discussed.

Teaching Public Administration: Key Themes 1996-2016

Science.gov (United States)

Fenwick, John

2018-01-01

In this article, the aim is to explore some of the key themes to emerge in the journal during the past two decades. Each selected theme will be reviewed in the light of issues raised in particular papers. The aim of this approach is, first, to facilitate reflection upon the contribution of the journal as its subject matter has moved from a concern…

Encapsulation of a Decision-Making Model to Optimize Supplier Selection via Structural Equation Modeling (SEM)

Science.gov (United States)

Sahul Hameed, Ruzanna; Thiruchelvam, Sivadass; Nasharuddin Mustapha, Kamal; Che Muda, Zakaria; Mat Husin, Norhayati; Ezanee Rusli, Mohd; Yong, Lee Choon; Ghazali, Azrul; Itam, Zarina; Hakimie, Hazlinda; Beddu, Salmia; Liyana Mohd Kamal, Nur

2016-03-01

This paper proposes a conceptual framework to compare criteria/factor that influence the supplier selection. A mixed methods approach comprising qualitative and quantitative survey will be used. The study intend to identify and define the metrics that key stakeholders at Public Works Department (PWD) believed should be used for supplier. The outcomes would foresee the possible initiatives to bring procurement in PWD to a strategic level. The results will provide a deeper understanding of drivers for supplier’s selection in the construction industry. The obtained output will benefit many parties involved in the supplier selection decision-making. The findings provides useful information and greater understanding of the perceptions that PWD executives hold regarding supplier selection and the extent to which these perceptions are consistent with findings from prior studies. The findings from this paper can be utilized as input for policy makers to outline any changes in the current procurement code of practice in order to enhance the degree of transparency and integrity in decision-making.

Key-value store with internal key-value storage interface

Science.gov (United States)

Bent, John M.; Faibish, Sorin; Ting, Dennis P. J.; Tzelnic, Percy; Gupta, Uday; Grider, Gary; Bonnie, David J.

2018-01-16

A key-value store is provided having one or more key-value storage interfaces. A key-value store on at least one compute node comprises a memory for storing a plurality of key-value pairs; and an abstract storage interface comprising a software interface module that communicates with at least one persistent storage device providing a key-value interface for persistent storage of one or more of the plurality of key-value pairs, wherein the software interface module provides the one or more key-value pairs to the at least one persistent storage device in a key-value format. The abstract storage interface optionally processes one or more batch operations on the plurality of key-value pairs. A distributed embodiment for a partitioned key-value store is also provided.

Health policy and integrated mental health care in the SADC region: strategic clarification using the Rainbow Model.

Science.gov (United States)

van Rensburg, André Janse; Fourie, Pieter

2016-01-01

Mental illness is a well-known challenge to global development, particularly in low-to-middle income countries. A key health systems response to mental illness is different models of integrated health care, especially popular in the South African Development Community (SADC) region. This complex construct is often not well-defined in health policy, hampering implementation efforts. A key development in this vein has been the Rainbow Model of integrated care, a comprehensive framework and taxonomy of integrated care based on the integrative functions of primary care. The purpose of this study was to explore the nature and strategic forms of integrated mental health care in selected SADC countries, specifically how integrated care is outlined in state-driven policies. Health policies from five SADC countries were analysed using the Rainbow Model as framework. Electronic copies of policy documents were transferred into NVivo 10, which aided in the framework analysis on the different types of integrated mental health care promoted in the countries assessed. Several Rainbow Model components were emphasised. Clinical integration strategies (coordination of person-focused care) such as centrality of client needs, case management and continuity were central considerations, while others such as patient education and client satisfaction were largely lacking. Professional integration (inter-professional partnerships) was mentioned in terms of agreements on interdisciplinary collaboration and performance management, while organisational integration (inter-organisational relationships) emerged under the guise of inter-organisational governance, population needs and interest management. Among others, available resources, population management and stakeholder management fed into system integration strategies (horizontally and vertically integrated systems), while functional integration strategies (financial, management and information system functions) included human resource

Potential Impact of Integrated Stigma Mitigation Interventions in Improving HIV/AIDS Service Delivery and Uptake for Key Populations in Senegal.

Science.gov (United States)

Lyons, Carrie E; Ketende, Sosthenes; Diouf, Daouda; Drame, Fatou M; Liestman, Benjamin; Coly, Karleen; Ndour, Cheikh; Turpin, Gnilane; Mboup, Souleymane; Diop, Karim; Toure-Kane, Coumba; Castor, Delivette; Leye-Diouf, Nafissatou; Baral, Stefan

2017-01-01

Men who have sex with men (MSM) and female sex workers (FSW) are consistently shown to have a higher burden of HIV compared with other adults in Senegal. This study, HIV Prevention 2.0, evaluates the impact of the 3-tiered integrated stigma mitigation interventions (ISMIs) approach to optimizing HIV service delivery for key populations in Senegal. Baseline assessment includes a questionnaire and biological testing for HIV. A proportion of participants enrolled into a 24-month longitudinal cohort with questionnaires and biological testing every 3 months. In these preliminary analyses, ISMIs are evaluated from participants in the cohort through uptake of HIV services and implementation outcomes. Overall, 724 MSM and 758 FSW participated in the baseline assessment. HIV prevalence is 30.2% (n = 219/724) among MSM and 5.3% (n = 40/758) among FSW. Fear of seeking health services among MSM is 17.7% (n = 128/724) at baseline, 10.5% (n = 18/172) at month 3, and 9.8% (n = 10/102) at month 6 (P intervention is effective in addressing stigma; however, loss to follow-up was 41.1% among MSM and 10% among FSW. Baseline data reinforce the need for stigma mitigation interventions, combined with enhanced linkage and retention to optimize HIV treatment. Preliminary results show high levels of HIV-related risk determinants and suggest the potential utility of the ISMI to decrease perceived stigma relating to engagement in HIV prevention, treatment, and care services among key populations in Senegal.

Models of Russia's Participation in Regional Economic Integration

Directory of Open Access Journals (Sweden)

Darya I. Ushkalova

2014-01-01

Full Text Available The article analyses models and mechanisms of Russia's participation in integration processes in Post-Soviet space in recent years. The article examines the model of integration of Customs Union Common Economic Space Eurasian Economic Union and particular mechanisms of its realization. It also examines key challenges to further development of integration in the frameworks of Eurasian Economic Union including exhausting of short-term and medium-term integration effects against a background of low level of economic cooperation and the lack of effective mechanism of interest coordination and decisionmaking similar to qualified majority. It concludes that deterioration of mutual trade dynamics in Customs Union is determined by fundamental factors, first of all, exhausting of medium-term integration effects which lead to extension of mutual trade immediately after Customs Union creation but do not change its qualitative characteristics in long-term outlook. The author shows an absence of significant long-term integration effects which were based on increase of domestic market capacity due to a modification of economic structure. It is founded that appearance of such long-term integration effects is possible only in the context of coalescence of national economies at the microlevel based on development of system of communications between enterprises including intrasectoral industrial cooperation. The article also analyses results of realization of Russia's strategy of interaction with states beyond Eurasian Economic Union based on open regionalism concept. The paper presents recommendation on perfection of tools of integration in and outside Eurasian Economic Union. In particular, creation of system of decentralized organizations is proposed, for the implementation of specific cooperation projects in selected areas, taking into account the multiplier effect of such a "point-aimed" action/

Progress in the development of integrated mental health care in Scotland

Directory of Open Access Journals (Sweden)

Kevin Woods

2002-06-01

Full Text Available The development of integrated care through the promotion of ‘partnership working’ is a key policy objective of the Scottish Executive, the administration responsible for health services in Scotland. This paper considers the extent to which this goal is being achieved in mental health services, particularly those for people with severe and enduring mental illness. Distinguishing between the horizontal and vertical integration of services, exploratory research was conducted to assess progress towards this objective by examining how far a range of functional activities in Primary Care Trusts (PCTs and their constituent Local Health Care Co-operatives (LHCCs were themselves becoming increasingly integrated. All PCTs in Scotland were surveyed by postal questionnaire, and followed up by detailed telephone interviews. Six LHCC areas were selected for detailed case study analysis. A Reference Group was used to discuss and review emerging themes from the fieldwork. The report suggests that faster progress is being made in the horizontal integration of services between health and social care organisations than is the case for vertical integration between primary health care and specialist mental health care services; and that there are significant gaps in the extent to which functional activities within Trusts are changing to support the development of integrated care. A number of models are briefly considered, including the idea of ‘intermediate care’ that might speed the process of integration.

Efficiently and easily integrating differential equations with JiTCODE, JiTCDDE, and JiTCSDE

Science.gov (United States)

Ansmann, Gerrit

2018-04-01

We present a family of Python modules for the numerical integration of ordinary, delay, or stochastic differential equations. The key features are that the user enters the derivative symbolically and it is just-in-time-compiled, allowing the user to efficiently integrate differential equations from a higher-level interpreted language. The presented modules are particularly suited for large systems of differential equations such as those used to describe dynamics on complex networks. Through the selected method of input, the presented modules also allow almost complete automatization of the process of estimating regular as well as transversal Lyapunov exponents for ordinary and delay differential equations. We conceptually discuss the modules' design, analyze their performance, and demonstrate their capabilities by application to timely problems.

Integral methods in low-frequency electromagnetics

CERN Document Server

Solin, Pavel; Karban, Pavel; Ulrych, Bohus

2009-01-01

A modern presentation of integral methods in low-frequency electromagnetics This book provides state-of-the-art knowledge on integral methods in low-frequency electromagnetics. Blending theory with numerous examples, it introduces key aspects of the integral methods used in engineering as a powerful alternative to PDE-based models. Readers will get complete coverage of: The electromagnetic field and its basic characteristics An overview of solution methods Solutions of electromagnetic fields by integral expressions Integral and integrodifferential methods

76 FR 48807 - Public Key Infrastructure (PKI) Certificate Action Form

Science.gov (United States)

2011-08-09

... Infrastructure (PKI) technology to support electronic commerce between the USPTO and its customers. PKI is a set... security for its electronic commerce systems, the USPTO uses PKI technology to protect the integrity and... DEPARTMENT OF COMMERCE United States Patent and Trademark Office Public Key Infrastructure (PKI...

Key Frame Extraction in the Summary Space.

Science.gov (United States)

Li, Xuelong; Zhao, Bin; Lu, Xiaoqiang; Xuelong Li; Bin Zhao; Xiaoqiang Lu; Lu, Xiaoqiang; Li, Xuelong; Zhao, Bin

2018-06-01

Key frame extraction is an efficient way to create the video summary which helps users obtain a quick comprehension of the video content. Generally, the key frames should be representative of the video content, meanwhile, diverse to reduce the redundancy. Based on the assumption that the video data are near a subspace of a high-dimensional space, a new approach, named as key frame extraction in the summary space, is proposed for key frame extraction in this paper. The proposed approach aims to find the representative frames of the video and filter out similar frames from the representative frame set. First of all, the video data are mapped to a high-dimensional space, named as summary space. Then, a new representation is learned for each frame by analyzing the intrinsic structure of the summary space. Specifically, the learned representation can reflect the representativeness of the frame, and is utilized to select representative frames. Next, the perceptual hash algorithm is employed to measure the similarity of representative frames. As a result, the key frame set is obtained after filtering out similar frames from the representative frame set. Finally, the video summary is constructed by assigning the key frames in temporal order. Additionally, the ground truth, created by filtering out similar frames from human-created summaries, is utilized to evaluate the quality of the video summary. Compared with several traditional approaches, the experimental results on 80 videos from two datasets indicate the superior performance of our approach.

A Recommended Set of Key Arctic Indicators

Science.gov (United States)

Stanitski, D.; Druckenmiller, M.; Fetterer, F. M.; Gerst, M.; Intrieri, J. M.; Kenney, M. A.; Meier, W.; Overland, J. E.; Stroeve, J.; Trainor, S.

2017-12-01

The Arctic is an interconnected and environmentally sensitive system of ice, ocean, land, atmosphere, ecosystems, and people. From local to pan-Arctic scales, the area has already undergone major changes in physical and societal systems and will continue at a pace that is greater than twice the global average. Key Arctic indicators can quantify these changes. Indicators serve as the bridge between complex information and policy makers, stakeholders, and the general public, revealing trends and information people need to make important socioeconomic decisions. This presentation evaluates and compiles more than 70 physical, biological, societal and economic indicators into an approachable summary that defines the changing Arctic. We divided indicators into "existing," "in development," "possible," and "aspirational". In preparing a paper on Arctic Indicators for a special issue of the journal Climatic Change, our group established a set of selection criteria to identify indicators to specifically guide decision-makers in their responses to climate change. A goal of the analysis is to select a manageable composite list of recommended indicators based on sustained, reliable data sources with known user communities. The selected list is also based on the development of a conceptual model that identifies components and processes critical to our understanding of the Arctic region. This list of key indicators is designed to inform the plans and priorities of multiple groups such as the U.S. Global Change Research Program (USGCRP), Interagency Arctic Research Policy Committee (IARPC), and the Arctic Council.

Integrating eHealth in HIV/AIDS intervention programmes in South Africa

Directory of Open Access Journals (Sweden)

Babasile D. Osunyomi

2015-03-01

Objective: The key aim of this article is to explore the status quo of the implementation of information and communication technologies (ICTs in selected intervention programmes in the South African HIV/AIDS care delivery value chain. The contribution of this article is the mapping of key intervention activities along an HIV care value chain and to suggest a roadmap towards the integration of ICTs in service delivery programmes. Method: 20 managers of HIV/AIDS intervention programmes were surveyed, followed by semi-structured in-depth interviews with these respondents. A further five in-depth interviews were conducted with experts in the ICT area for exploring the uses of and barriers to integrating ICTs in the HIV/AIDS care delivery value chain. Results: The researchers mapped the barriers to implementation and ICT tools utilised within the HIV/AIDS care delivery value chain, which proves to be a useful tool to explore the status quo of technology in such service delivery programmes. The researchers then considered the wider policy environment and provided a roadmap based on the analysis and the South Africa eHealth strategy for driving development in this sector. Conclusion: The authors found that South Africa’s eHealth environment is still nascent and that the South African eHealth strategy does not place enough emphasis on systems integration and stakeholder engagement or the planning and process of uptake of ICTs by target audiences.

Electronic viewbox: An integrated image diagnostic working station

International Nuclear Information System (INIS)

Minato, K.; Komori, M.; Hirakawa, A.; Kuwahara, M.; Yonekura, Y.; Torizuka, K.; Brill, A.B.

1985-01-01

Recent development in medical imaging technology have been introducing variety of digital images in clinical medicine, and handling these multi-modality digital images in one place is needed for efficient clinical diagnosis. The authors proposed a concept of an integrated image diagnostic working station, in which a physician can look into all clinical images, can select any key image for diagnosis and can read it in detail. A prototype working station named ''Electronic Viewbox'' has been developed for this purpose. It has three distinctive features. 1. The stored images of a patient are shown at a glance. In order to achieve this function, each original image is attached to a small image, where the data are compressed to reserve the essence of the image, and many of these small images are displayed on a CRT screen. This small image is used as an index for picking up a key image in the archived clinical images. 2. The working station is compact enough to be set on a desk. Only two CRTs and a pointing device are assembled. These two CRT screens are used mutually for retrieving key images and for displaying the original images. 3. All operations can be done interactively using cursor and icons

Key interventions and quality indicators for quality improvement of STEMI care: a RAND Delphi survey.

Science.gov (United States)

Aeyels, Daan; Sinnaeve, Peter R; Claeys, Marc J; Gevaert, Sofie; Schoors, Danny; Sermeus, Walter; Panella, Massimiliano; Coeckelberghs, Ellen; Bruyneel, Luk; Vanhaecht, Kris

2017-12-13

Identification, selection and validation of key interventions and quality indicators for improvement of in hospital quality of care for ST-elevated myocardial infarction (STEMI) patients. A structured literature review was followed by a RAND Delphi Survey. A purposively selected multidisciplinary expert panel of cardiologists, nurse managers and quality managers selected and validated key interventions and quality indicators prior for quality improvement for STEMI. First, 34 experts (76% response rate) individually assessed the appropriateness of items to quality improvement on a nine point Likert scale. Twenty-seven key interventions, 16 quality indicators at patient level and 27 quality indicators at STEMI care programme level were selected. Eighteen additional items were suggested. Experts received personal feedback, benchmarking their score with group results (response rate, mean, median and content validity index). Consequently, 32 experts (71% response rate) openly discussed items with an item-content validity index above 75%. By consensus, the expert panel validated a final set of 25 key interventions, 13 quality indicators at patient level and 20 quality indicators at care programme level prior for improvement of in hospital care for STEMI. A structured literature review and multidisciplinary expertise was combined to validate a set of key interventions and quality indicators prior for improvement of care for STEMI. The results allow researchers and hospital staff to evaluate and support quality improvement interventions in a large cohort within the context of a health care system.

The ECE Pre-Service Teachers' Perception on Factors Affecting the Integration of Educational Computer Games in Two Conditions: Selecting versus Redesigning

Science.gov (United States)

Sancar Tokmak, Hatice; Ozgelen, Sinan

2013-01-01

This case study aimed to examine early childhood education (ECE) pre-service teachers' perception on the factors affecting integration of educational computer games to their instruction in two areas: selecting and redesigning. Twenty-six ECE pre-service teachers participated in the study. The data was collected through open-ended questionnaires,…

Virtual-optical information security system based on public key infrastructure

Science.gov (United States)

Peng, Xiang; Zhang, Peng; Cai, Lilong; Niu, Hanben

2005-01-01

A virtual-optical based encryption model with the aid of public key infrastructure (PKI) is presented in this paper. The proposed model employs a hybrid architecture in which our previously published encryption method based on virtual-optics scheme (VOS) can be used to encipher and decipher data while an asymmetric algorithm, for example RSA, is applied for enciphering and deciphering the session key(s). The whole information security model is run under the framework of international standard ITU-T X.509 PKI, which is on basis of public-key cryptography and digital signatures. This PKI-based VOS security approach has additional features like confidentiality, authentication, and integrity for the purpose of data encryption under the environment of network. Numerical experiments prove the effectiveness of the method. The security of proposed model is briefly analyzed by examining some possible attacks from the viewpoint of a cryptanalysis.

Advertising media selection and planning

NARCIS (Netherlands)

Moorman, M.; Neijens, P.C.; Smit, E.G.; Belch, M.A.; Belch, G.E.

2010-01-01

Reach, frequency, and timing are key concepts in selecting TV, radio, newspapers, magazines, out-of-home, direct mail, Internet, and other media for advertising campaigns. We discuss these concepts and their role in media selection and media planning processes. We also describe media and audience

The Role of Technical Advances in the Adoption and Integration of Patient-Reported Outcomes in Clinical Care

Science.gov (United States)

Jensen, Roxanne E.; Rothrock, Nan E.; DeWitt, Esi Morgan; Spiegel, Brennan; Tucker, Carole A.; Crane, Heidi M.; Forrest, Christopher B.; Patrick, Donald L.; Fredericksen, Rob; Shulman, Lisa M.; Cella, David; Crane, Paul K.

2016-01-01

Background Patient-reported outcomes (PROs) are gaining recognition as key measures for improving the quality of patient care in clinical care settings. Three factors have made the implementation of PROs in clinical care more feasible: increased use of modern measurement methods in PRO design and validation, rapid progression of technology (e.g., touch screen tablets, Internet accessibility, and electronic health records (EHRs)), and greater demand for measurement and monitoring of PROs by regulators, payers, accreditors, and professional organizations. As electronic PRO collection and reporting capabilities have improved, the challenges of collecting PRO data have changed. Objectives To update information on PRO adoption considerations in clinical care, highlighting electronic and technical advances with respect to measure selection, clinical workflow, data infrastructure, and outcomes reporting. Methods Five practical case studies across diverse healthcare settings and patient populations are used to explore how implementation barriers were addressed to promote the successful integration of PRO collection into the clinical workflow. The case studies address selecting and reporting of relevant content, workflow integration, pre-visit screening, effective evaluation, and EHR integration. Conclusions These case studies exemplify elements of well-designed electronic systems, including response automation, tailoring of item selection and reporting algorithms, flexibility of collection location, and integration with patient health care data elements. They also highlight emerging logistical barriers in this area, such as the need for specialized technological and methodological expertise, and design limitations of current electronic data capture systems. PMID:25588135

GENERALIZED MATRIXES OF GALOIS PROTOCOLS EXCHANGE ENCRYPTION KEYS

Directory of Open Access Journals (Sweden)

Anatoly Beletsky

2016-03-01

Full Text Available The methods of construction of matrix formation the secret protocols legalized subscribers of public communications networks encryption keys. Based key exchange protocols laid asymmetric cryptography algorithms. The solution involves the calculation of one-way functions and is based on the use of generalized Galois arrays of isomorphism relationship with forming elements, and depending on the selected irreducible polynomial generating matrix. A simple method for constructing generalized Galois matrix by the method of filling the diagonal. In order to eliminate the isomorphism of Galois arrays and their constituent elements, limiting the possibility of building one-way functions, Galois matrix subjected to similarity transformation carried out by means of permutation matrices. The variant of the organization of the algebraic attacks on encryption keys sharing protocols and discusses options for easing the consequences of an attack.

Integrated homecare to bridge transition from health care to social services in EU

DEFF Research Database (Denmark)

Larsen, Torben

2009-01-01

to develop a turn-key-solution for better clinical continuity to European health regions. Method: The general framework of the project is the international concept of health technology assessment (HTA) as implemented in the EUnetHTA Core Model focusing nine analytical domains. Based on a systematic...... dominant intervention. 3) Based on a SWOT-analysis a meso-strategy implementing IHC at a regional level is planned to combine the advantages of a goal-directed centralized approach with the adaption to local conditions in a decentralized approach. Discussion: Clinical and social IHC-network...... literature review of trials on integrated care integrated homecare (IHC) is defined and selected as prototype for continued rehabilitation of disabled chronic patients. Preliminary results: 1) The efficacy of IHC are hypothesized to have a common neuroeconomic explanation in the finding that the blood...

Model of key success factors for Business Intelligence implementation

Directory of Open Access Journals (Sweden)

Peter Mesaros

2016-07-01

Full Text Available New progressive technologies recorded growth in every area. Information-communication technologies facilitate the exchange of information and it facilitates management of everyday activities in enterprises. Specific modules (such as Business Intelligence facilitate decision-making. Several studies have demonstrated the positive impact of Business Intelligence to decision-making. The first step is to put in place the enterprise. The implementation process is influenced by many factors. This article discusses the issue of key success factors affecting to successful implementation of Business Intelligence. The article describes the key success factors for successful implementation and use of Business Intelligence based on multiple studies. The main objective of this study is to verify the effects and dependence of selected factors and proposes a model of key success factors for successful implementation of Business Intelligence. Key success factors and the proposed model are studied in Slovak enterprises.

Expression profiles of variation integration genes in bladder urothelial carcinoma.

Science.gov (United States)

Wang, J M; Wang, Y Q; Gao, Z L; Wu, J T; Shi, B K; Yu, C C

2014-04-30

Bladder cancer is a common cancer worldwide and its incidence continues to increase. There are approximately 261,000 cases of bladder cancer resulting in 115,000 deaths annually. This study aimed to integrate bladder cancer genome copy number variation information and bladder cancer gene transcription level expression data to construct a causal-target module network of the range of bladder cancer-related genomes. Here, we explored the control mechanism underlying bladder cancer phenotype expression regulation by the major bladder cancer genes. We selected 22 modules as the initial module network to expand the search to screen more networks. After bootstrapping 100 times, we obtained 16 key regulators. These 16 key candidate regulatory genes were further expanded to identify the expression changes of 11,676 genes in 275 modules, which may all have the same regulation. In conclusion, a series of modules associated with the terms 'cancer' or 'bladder' were considered to constitute a potential network.

Public key infrastructure for DOE security research

Energy Technology Data Exchange (ETDEWEB)

Aiken, R.; Foster, I.; Johnston, W.E. [and others

1997-06-01

This document summarizes the Department of Energy`s Second Joint Energy Research/Defence Programs Security Research Workshop. The workshop, built on the results of the first Joint Workshop which reviewed security requirements represented in a range of mission-critical ER and DP applications, discussed commonalties and differences in ER/DP requirements and approaches, and identified an integrated common set of security research priorities. One significant conclusion of the first workshop was that progress in a broad spectrum of DOE-relevant security problems and applications could best be addressed through public-key cryptography based systems, and therefore depended upon the existence of a robust, broadly deployed public-key infrastructure. Hence, public-key infrastructure ({open_quotes}PKI{close_quotes}) was adopted as a primary focus for the second workshop. The Second Joint Workshop covered a range of DOE security research and deployment efforts, as well as summaries of the state of the art in various areas relating to public-key technologies. Key findings were that a broad range of DOE applications can benefit from security architectures and technologies built on a robust, flexible, widely deployed public-key infrastructure; that there exists a collection of specific requirements for missing or undeveloped PKI functionality, together with a preliminary assessment of how these requirements can be met; that, while commercial developments can be expected to provide many relevant security technologies, there are important capabilities that commercial developments will not address, due to the unique scale, performance, diversity, distributed nature, and sensitivity of DOE applications; that DOE should encourage and support research activities intended to increase understanding of security technology requirements, and to develop critical components not forthcoming from other sources in a timely manner.

Integrating Product and Technology Development

DEFF Research Database (Denmark)

Meijer, Ellen Brilhuis; Pigosso, Daniela Cristina Antelmi; McAloone, Tim C.

2016-01-01

.g. managing dependencies) and opportunities (e.g. streamlining development). This paper presents five existing reference models for technology development (TD), which were identified via a systematic literature review, where their possible integration with product development (PD) reference models......Although dual innovation projects, defined in this article as the concurrent development of products and technologies, often occur in industry, these are only scarcely supported methodologically. Limited research has been done about dual innovation projects and their inherent challenges (e...... was investigated. Based on the specific characteristics desired for dual innovation projects, such as integrated product development and coverage of multiple development stages, a set of selection criteria was employed to select suitable PD and TD reference models. The integration and adaptation of the selected...

Integrated, Continuous Emulsion Creamer.

Science.gov (United States)

Cochrane, Wesley G; Hackler, Amber L; Cavett, Valerie J; Price, Alexander K; Paegel, Brian M

2017-12-19

Automated and reproducible sample handling is a key requirement for high-throughput compound screening and currently demands heavy reliance on expensive robotics in screening centers. Integrated droplet microfluidic screening processors are poised to replace robotic automation by miniaturizing biochemical reactions to the droplet scale. These processors must generate, incubate, and sort droplets for continuous droplet screening, passively handling millions of droplets with complete uniformity, especially during the key step of sample incubation. Here, we disclose an integrated microfluidic emulsion creamer that packs ("creams") assay droplets by draining away excess oil through microfabricated drain channels. The drained oil coflows with creamed emulsion and then reintroduces the oil to disperse the droplets at the circuit terminus for analysis. Creamed emulsion assay incubation time dispersion was 1.7%, 3-fold less than other reported incubators. The integrated, continuous emulsion creamer (ICEcreamer) was used to miniaturize and optimize measurements of various enzymatic activities (phosphodiesterase, kinase, bacterial translation) under multiple- and single-turnover conditions. Combining the ICEcreamer with current integrated microfluidic DNA-encoded library bead processors eliminates potentially cumbersome instrumentation engineering challenges and is compatible with assays of diverse target class activities commonly investigated in drug discovery.

Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism

DEFF Research Database (Denmark)

Hu, Zheng; Zhu, Da; Wang, Wei

2015-01-01

Human papillomavirus (HPV) integration is a key genetic event in cervical carcinogenesis1. By conducting whole-genome sequencing and high-throughput viral integration detection, we identified 3,667 HPV integration breakpoints in 26 cervical intraepithelial neoplasias, 104 cervical carcinomas and ...

Compressors selection and sizing

CERN Document Server

Brown, Royce N

2005-01-01

This practical reference provides in-depth information required to understand and properly estimate compressor capabilities and to select the proper designs. Engineers and students will gain a thorough understanding of compression principles, equipment, applications, selection, sizing, installation, and maintenance. The many examples clearly illustrate key aspects to help readers understand the ""real world"" of compressor technology.Compressors: Selection and Sizing, third edition is completely updated with new API standards. Additions requested by readers include a new section on di

The European Integrated Tokamak Modelling (ITM) effort: achievements and first physics results

International Nuclear Information System (INIS)

Falchetto, G.L.; Nardon, E.; Artaud, J.F.; Basiuk, V.; Huynh, Ph.; Imbeaux, F.; Coster, D.; Scott, B.D.; Coelho, R.; Alves, L.L.; Bizarro, João P.S.; Ferreira, J.; Figueiredo, A.; Figini, L.; Nowak, S.; Farina, D.; Kalupin, D.; Boulbe, C.; Faugeras, B.; Dinklage, A.

2014-01-01

A selection of achievements and first physics results are presented of the European Integrated Tokamak Modelling Task Force (EFDA ITM-TF) simulation framework, which aims to provide a standardized platform and an integrated modelling suite of validated numerical codes for the simulation and prediction of a complete plasma discharge of an arbitrary tokamak. The framework developed by the ITM-TF, based on a generic data structure including both simulated and experimental data, allows for the development of sophisticated integrated simulations (workflows) for physics application. The equilibrium reconstruction and linear magnetohydrodynamic (MHD) stability simulation chain was applied, in particular, to the analysis of the edge MHD stability of ASDEX Upgrade type-I ELMy H-mode discharges and ITER hybrid scenario, demonstrating the stabilizing effect of an increased Shafranov shift on edge modes. Interpretive simulations of a JET hybrid discharge were performed with two electromagnetic turbulence codes within ITM infrastructure showing the signature of trapped-electron assisted ITG turbulence. A successful benchmark among five EC beam/ray-tracing codes was performed in the ITM framework for an ITER inductive scenario for different launching conditions from the equatorial and upper launcher, showing good agreement of the computed absorbed power and driven current. Selected achievements and scientific workflow applications targeting key modelling topics and physics problems are also presented, showing the current status of the ITM-TF modelling suite. (paper)

Integrative analysis of single nucleotide polymorphisms and gene expression efficiently distinguishes samples from closely related ethnic populations

Directory of Open Access Journals (Sweden)

Yang Hsin-Chou

2012-07-01

Full Text Available Abstract Background Ancestry informative markers (AIMs are a type of genetic marker that is informative for tracing the ancestral ethnicity of individuals. Application of AIMs has gained substantial attention in population genetics, forensic sciences, and medical genetics. Single nucleotide polymorphisms (SNPs, the materials of AIMs, are useful for classifying individuals from distinct continental origins but cannot discriminate individuals with subtle genetic differences from closely related ancestral lineages. Proof-of-principle studies have shown that gene expression (GE also is a heritable human variation that exhibits differential intensity distributions among ethnic groups. GE supplies ethnic information supplemental to SNPs; this motivated us to integrate SNP and GE markers to construct AIM panels with a reduced number of required markers and provide high accuracy in ancestry inference. Few studies in the literature have considered GE in this aspect, and none have integrated SNP and GE markers to aid classification of samples from closely related ethnic populations. Results We integrated a forward variable selection procedure into flexible discriminant analysis to identify key SNP and/or GE markers with the highest cross-validation prediction accuracy. By analyzing genome-wide SNP and/or GE markers in 210 independent samples from four ethnic groups in the HapMap II Project, we found that average testing accuracies for a majority of classification analyses were quite high, except for SNP-only analyses that were performed to discern study samples containing individuals from two close Asian populations. The average testing accuracies ranged from 0.53 to 0.79 for SNP-only analyses and increased to around 0.90 when GE markers were integrated together with SNP markers for the classification of samples from closely related Asian populations. Compared to GE-only analyses, integrative analyses of SNP and GE markers showed comparable testing

KeyWare: an open wireless distributed computing environment

Science.gov (United States)

Shpantzer, Isaac; Schoenfeld, Larry; Grindahl, Merv; Kelman, Vladimir

1995-12-01

Deployment of distributed applications in the wireless domain lack equivalent tools, methodologies, architectures, and network management that exist in LAN based applications. A wireless distributed computing environment (KeyWareTM) based on intelligent agents within a multiple client multiple server scheme was developed to resolve this problem. KeyWare renders concurrent application services to wireline and wireless client nodes encapsulated in multiple paradigms such as message delivery, database access, e-mail, and file transfer. These services and paradigms are optimized to cope with temporal and spatial radio coverage, high latency, limited throughput and transmission costs. A unified network management paradigm for both wireless and wireline facilitates seamless extensions of LAN- based management tools to include wireless nodes. A set of object oriented tools and methodologies enables direct asynchronous invocation of agent-based services supplemented by tool-sets matched to supported KeyWare paradigms. The open architecture embodiment of KeyWare enables a wide selection of client node computing platforms, operating systems, transport protocols, radio modems and infrastructures while maintaining application portability.

Integrated Multiscale Latent Variable Regression and Application to Distillation Columns

Directory of Open Access Journals (Sweden)

Muddu Madakyaru

2013-01-01

Full Text Available Proper control of distillation columns requires estimating some key variables that are challenging to measure online (such as compositions, which are usually estimated using inferential models. Commonly used inferential models include latent variable regression (LVR techniques, such as principal component regression (PCR, partial least squares (PLS, and regularized canonical correlation analysis (RCCA. Unfortunately, measured practical data are usually contaminated with errors, which degrade the prediction abilities of inferential models. Therefore, noisy measurements need to be filtered to enhance the prediction accuracy of these models. Multiscale filtering has been shown to be a powerful feature extraction tool. In this work, the advantages of multiscale filtering are utilized to enhance the prediction accuracy of LVR models by developing an integrated multiscale LVR (IMSLVR modeling algorithm that integrates modeling and feature extraction. The idea behind the IMSLVR modeling algorithm is to filter the process data at different decomposition levels, model the filtered data from each level, and then select the LVR model that optimizes a model selection criterion. The performance of the developed IMSLVR algorithm is illustrated using three examples, one using synthetic data, one using simulated distillation column data, and one using experimental packed bed distillation column data. All examples clearly demonstrate the effectiveness of the IMSLVR algorithm over the conventional methods.

Predicting Key Events in the Popularity Evolution of Online Information.

Science.gov (United States)

Hu, Ying; Hu, Changjun; Fu, Shushen; Fang, Mingzhe; Xu, Wenwen

2017-01-01

The popularity of online information generally experiences a rising and falling evolution. This paper considers the "burst", "peak", and "fade" key events together as a representative summary of popularity evolution. We propose a novel prediction task-predicting when popularity undergoes these key events. It is of great importance to know when these three key events occur, because doing so helps recommendation systems, online marketing, and containment of rumors. However, it is very challenging to solve this new prediction task due to two issues. First, popularity evolution has high variation and can follow various patterns, so how can we identify "burst", "peak", and "fade" in different patterns of popularity evolution? Second, these events usually occur in a very short time, so how can we accurately yet promptly predict them? In this paper we address these two issues. To handle the first one, we use a simple moving average to smooth variation, and then a universal method is presented for different patterns to identify the key events in popularity evolution. To deal with the second one, we extract different types of features that may have an impact on the key events, and then a correlation analysis is conducted in the feature selection step to remove irrelevant and redundant features. The remaining features are used to train a machine learning model. The feature selection step improves prediction accuracy, and in order to emphasize prediction promptness, we design a new evaluation metric which considers both accuracy and promptness to evaluate our prediction task. Experimental and comparative results show the superiority of our prediction solution.

Predicting Key Events in the Popularity Evolution of Online Information.

Directory of Open Access Journals (Sweden)

Ying Hu

Full Text Available The popularity of online information generally experiences a rising and falling evolution. This paper considers the "burst", "peak", and "fade" key events together as a representative summary of popularity evolution. We propose a novel prediction task-predicting when popularity undergoes these key events. It is of great importance to know when these three key events occur, because doing so helps recommendation systems, online marketing, and containment of rumors. However, it is very challenging to solve this new prediction task due to two issues. First, popularity evolution has high variation and can follow various patterns, so how can we identify "burst", "peak", and "fade" in different patterns of popularity evolution? Second, these events usually occur in a very short time, so how can we accurately yet promptly predict them? In this paper we address these two issues. To handle the first one, we use a simple moving average to smooth variation, and then a universal method is presented for different patterns to identify the key events in popularity evolution. To deal with the second one, we extract different types of features that may have an impact on the key events, and then a correlation analysis is conducted in the feature selection step to remove irrelevant and redundant features. The remaining features are used to train a machine learning model. The feature selection step improves prediction accuracy, and in order to emphasize prediction promptness, we design a new evaluation metric which considers both accuracy and promptness to evaluate our prediction task. Experimental and comparative results show the superiority of our prediction solution.

Integrated management systems

CERN Document Server

Bugdol, Marek

2015-01-01

Examining the challenges of integrated management, this book explores the importance and potential benefits of using an integrated approach as a cross-functional concept of management. It covers not only standardized management systems (e.g. International Organization for Standardization), but also models of self-assessment, as well as different types of integration. Furthermore, it demonstrates how processes and systems can be integrated, and how management efficiency can be increased. The major part of this book focuses on management concepts which use integration as a key tool of management processes (e.g. the systematic approach, supply chain management, virtual and network organizations, processes management and total quality management). Case studies, illustrations, and tables are also provided to exemplify and illuminate the content, as well as examples of successful and failed integrations. Providing a particularly useful resource to managers and specialists involved in the improvement of organization...

ROLE AND IMPORTANCE OF KEY PERFORMANCE INDICATORS MEASUREMENT

Directory of Open Access Journals (Sweden)

Rade Stanković

2011-03-01

Full Text Available Key performance indicators are financial and non financial indicators that organizations use inorder to estimate and fortify how successful they are, aiming previously established long lastinggoals. Appropriate selection of indicators that will be used for measuring is of a greatest importance.Process organization of business is necessary to be constitute in order to realize such effective andefficient system or performance measuring via KPI. Process organization also implies customerorientation and necessary flexibility in nowadays condition of global competition.Explanation of process organization, the way of KPI selection, and practical example of KPImeasuring in Toyota dealerships are presented in this paper.

Integrated Ecological River Health Assessments, Based on Water Chemistry, Physical Habitat Quality and Biological Integrity

Directory of Open Access Journals (Sweden)

Ji Yoon Kim

2015-11-01

Full Text Available This study evaluated integrative river ecosystem health using stressor-based models of physical habitat health, chemical water health, and biological health of fish and identified multiple-stressor indicators influencing the ecosystem health. Integrated health responses (IHRs, based on star-plot approach, were calculated from qualitative habitat evaluation index (QHEI, nutrient pollution index (NPI, and index of biological integrity (IBI in four different longitudinal regions (Groups I–IV. For the calculations of IHRs values, multi-metric QHEI, NPI, and IBI models were developed and their criteria for the diagnosis of the health were determined. The longitudinal patterns of the river were analyzed by a self-organizing map (SOM model and the key major stressors in the river were identified by principal component analysis (PCA. Our model scores of integrated health responses (IHRs suggested that mid-stream and downstream regions were impaired, and the key stressors were closely associated with nutrient enrichment (N and P and organic matter pollutions from domestic wastewater disposal plants and urban sewage. This modeling approach of IHRs may be used as an effective tool for evaluations of integrative ecological river health..

Key Distribution and Changing Key Cryptosystem Based on Phase Retrieval Algorithm and RSA Public-Key Algorithm

Directory of Open Access Journals (Sweden)

Tieyu Zhao

2015-01-01

Full Text Available The optical image encryption has attracted more and more researchers’ attention, and the various encryption schemes have been proposed. In existing optical cryptosystem, the phase functions or images are usually used as the encryption keys, and it is difficult that the traditional public-key algorithm (such as RSA, ECC, etc. is used to complete large numerical key transfer. In this paper, we propose a key distribution scheme based on the phase retrieval algorithm and the RSA public-key algorithm, which solves the problem for the key distribution in optical image encryption system. Furthermore, we also propose a novel image encryption system based on the key distribution principle. In the system, the different keys can be used in every encryption process, which greatly improves the security of the system.

TreePOD: Sensitivity-Aware Selection of Pareto-Optimal Decision Trees.

Science.gov (United States)

Muhlbacher, Thomas; Linhardt, Lorenz; Moller, Torsten; Piringer, Harald

2018-01-01

Balancing accuracy gains with other objectives such as interpretability is a key challenge when building decision trees. However, this process is difficult to automate because it involves know-how about the domain as well as the purpose of the model. This paper presents TreePOD, a new approach for sensitivity-aware model selection along trade-offs. TreePOD is based on exploring a large set of candidate trees generated by sampling the parameters of tree construction algorithms. Based on this set, visualizations of quantitative and qualitative tree aspects provide a comprehensive overview of possible tree characteristics. Along trade-offs between two objectives, TreePOD provides efficient selection guidance by focusing on Pareto-optimal tree candidates. TreePOD also conveys the sensitivities of tree characteristics on variations of selected parameters by extending the tree generation process with a full-factorial sampling. We demonstrate how TreePOD supports a variety of tasks involved in decision tree selection and describe its integration in a holistic workflow for building and selecting decision trees. For evaluation, we illustrate a case study for predicting critical power grid states, and we report qualitative feedback from domain experts in the energy sector. This feedback suggests that TreePOD enables users with and without statistical background a confident and efficient identification of suitable decision trees.

Discovering New Variable Stars at Key Stage 3

Science.gov (United States)

Chubb, Katy; Hood, Rosie; Wilson, Thomas; Holdship, Jonathan; Hutton, Sarah

2017-01-01

Details of the London pilot of the "Discovery Project" are presented, where university-based astronomers were given the chance to pass on some real and applied knowledge of astronomy to a group of selected secondary school pupils. It was aimed at students in Key Stage 3 of their education, allowing them to be involved in real…

The Integrated Renovation Process

DEFF Research Database (Denmark)

Galiotto, Nicolas; Heiselberg, Per; Knudstrup, Mary-Ann

The Integrated Renovation Process (IRP) is a user customized methodology based on judiciously selected constructivist and interactive multi-criteria decision making methods (Galiotto, Heiselberg, & Knudstrup, 2014 (expected)). When applied for home renovation, the Integrated Renovation Process...

Integrated Approach to Reconstruction of Microbial Regulatory Networks

Energy Technology Data Exchange (ETDEWEB)

Rodionov, Dmitry A [Sanford-Burnham Medical Research Institute; Novichkov, Pavel S [Lawrence Berkeley National Laboratory

2013-11-04

This project had the goal(s) of development of integrated bioinformatics platform for genome-scale inference and visualization of transcriptional regulatory networks (TRNs) in bacterial genomes. The work was done in Sanford-Burnham Medical Research Institute (SBMRI, P.I. D.A. Rodionov) and Lawrence Berkeley National Laboratory (LBNL, co-P.I. P.S. Novichkov). The developed computational resources include: (1) RegPredict web-platform for TRN inference and regulon reconstruction in microbial genomes, and (2) RegPrecise database for collection, visualization and comparative analysis of transcriptional regulons reconstructed by comparative genomics. These analytical resources were selected as key components in the DOE Systems Biology KnowledgeBase (SBKB). The high-quality data accumulated in RegPrecise will provide essential datasets of reference regulons in diverse microbes to enable automatic reconstruction of draft TRNs in newly sequenced genomes. We outline our progress toward the three aims of this grant proposal, which were: Develop integrated platform for genome-scale regulon reconstruction; Infer regulatory annotations in several groups of bacteria and building of reference collections of microbial regulons; and Develop KnowledgeBase on microbial transcriptional regulation.

Efficient Key Management System for Large-scale Smart RFID Applications

Directory of Open Access Journals (Sweden)

Mohammad Fal Sadikin

2015-08-01

Full Text Available Due to low-cost and its practical solution, the integration of RFID tag to the sensor node called smart RFID has become prominent solution in various fields including industrial applications. Nevertheless, the constrained nature of smart RFID system introduces tremendous security and privacy problem. One of them is the problem in key management system. Indeed, it is not feasible to recall all RFID tags in order to update their security properties (e.g. update their private keys. On the other hand, using common key management solution like standard TLS/SSL is too heavy-weight that can drain and overload the limited resources. Furthermore, most of existing solutions are highly susceptible to various threats reaching from privacy threats, physical attacks to various technics of Man-in-the-Middle attacks. This paper introduces novel key management system, tailored to the limited resources of smart RFID system. It proposes light-weight mutual authentication and identity protection to mitigate the existing threats.

George's secret key to the universe

CERN Document Server

Hawking, Lucy; Galfard, Christophe; Parsons, Gary

2007-01-01

In their bestselling book for young readers, noted physicist Stephen Hawking and his daughter, Lucy, provide a grand and funny adventure that explains fascinating information about our universe, including Dr. Hawking's latest ideas about black holes. It's the story of George, who's taken through the vastness of space by a scientist, his daughter, and their super-computer named Cosmos. George's Secret Key to the Universe was a New York Times bestseller and a selection of Al's Book Club on the Today show.

Information security system based on virtual-optics imaging methodology and public key infrastructure

Science.gov (United States)

Peng, Xiang; Zhang, Peng; Cai, Lilong

In this paper, we present a virtual-optical based information security system model with the aid of public-key-infrastructure (PKI) techniques. The proposed model employs a hybrid architecture in which our previously published encryption algorithm based on virtual-optics imaging methodology (VOIM) can be used to encipher and decipher data while an asymmetric algorithm, for example RSA, is applied for enciphering and deciphering the session key(s). For an asymmetric system, given an encryption key, it is computationally infeasible to determine the decryption key and vice versa. The whole information security model is run under the framework of PKI, which is on basis of public-key cryptography and digital signatures. This PKI-based VOIM security approach has additional features like confidentiality, authentication, and integrity for the purpose of data encryption under the environment of network.

Integration of Formal Job Hazard Analysis and ALARA Work Practice

International Nuclear Information System (INIS)

NELSEN, D.P.

2002-01-01

ALARA work practices have traditionally centered on reducing radiological exposure and controlling contamination. As such, ALARA policies and procedures are not well suited to a wide range of chemical and human health issues. Assessing relative risk, identifying appropriate engineering/administrative controls and selecting proper Personal Protective Equipment (PPE) for non nuclear work activities extends beyond the limitations of traditional ALARA programs. Forging a comprehensive safety management program in today's (2002) work environment requires a disciplined dialog between health and safety professionals (e.g. safety, engineering, environmental, quality assurance, industrial hygiene, ALARA, etc.) and personnel working in the field. Integrating organizational priorities, maintaining effective pre-planning of work and supporting a team-based approach to safety management represents today's hallmark of safety excellence. Relying on the mandates of any single safety program does not provide industrial hygiene with the tools necessary to implement an integrated safety program. The establishment of tools and processes capable of sustaining a comprehensive safety program represents a key responsibility of industrial hygiene. Fluor Hanford has built integrated safety management around three programmatic attributes: (1) Integration of radiological, chemical and ergonomic issues under a single program. (2) Continuous improvement in routine communications among work planning/scheduling, job execution and management. (3) Rapid response to changing work conditions, formalized work planning and integrated worker involvement

First-Principles Integrated Adsorption Modeling for Selective Capture of Uranium from Seawater by Polyamidoxime Sorbent Materials.

Science.gov (United States)

Ladshaw, Austin P; Ivanov, Alexander S; Das, Sadananda; Bryantsev, Vyacheslav S; Tsouris, Costas; Yiacoumi, Sotira

2018-04-18

Nuclear power is a relatively carbon-free energy source that has the capacity to be utilized today in an effort to stem the tides of global warming. The growing demand for nuclear energy, however, could put significant strain on our uranium ore resources, and the mining activities utilized to extract that ore can leave behind long-term environmental damage. A potential solution to enhance the supply of uranium fuel is to recover uranium from seawater using amidoximated adsorbent fibers. This technology has been studied for decades but is currently plagued by the material's relatively poor selectivity of uranium over its main competitor vanadium. In this work, we investigate the binding schemes between uranium, vanadium, and the amidoxime functional groups on the adsorbent surface. Using quantum chemical methods, binding strengths are approximated for a set of complexation reactions between uranium and vanadium with amidoxime functionalities. Those approximations are then coupled with a comprehensive aqueous adsorption model developed in this work to simulate the adsorption of uranium and vanadium under laboratory conditions. Experimental adsorption studies with uranium and vanadium over a wide pH range are performed, and the data collected are compared against simulation results to validate the model. It was found that coupling ab initio calculations with process level adsorption modeling provides accurate predictions of the adsorption capacity and selectivity of the sorbent materials. Furthermore, this work demonstrates that this multiscale modeling paradigm could be utilized to aid in the selection of superior ligands or ligand compositions for the selective capture of metal ions. Therefore, this first-principles integrated modeling approach opens the door to the in silico design of next-generation adsorbents with potentially superior efficiency and selectivity for uranium over vanadium in seawater.

Global Sourcing and Firm Selection

DEFF Research Database (Denmark)

Kohler, Wilhelm; Smolka, Marcel

2014-01-01

We analyze the sourcing strategies of firms active in the Spanish manufacturing sector. We show that firms that select strategies of vertical integration and of foreign sourcing ex post tend to have been more productive, ex ante, than other firms.......We analyze the sourcing strategies of firms active in the Spanish manufacturing sector. We show that firms that select strategies of vertical integration and of foreign sourcing ex post tend to have been more productive, ex ante, than other firms....

The Social-Financial Responsible Reporting – The Key for Integrated Reporting

OpenAIRE

Iulia Jianu

2012-01-01

General purpose of financial statements is to satisfy the needs of users who are not in the position to require of the entity to prepare reports tailored to their particular information needs. Because the public is one of these users interested of social information and because the financial statement do not provide sufficient social information to satisfy these needs, the study demonstrate the need to integrate the responsible social reporting into financial reporting. In order to support th...

Enterprise Application Integration Using Java Technologies

Directory of Open Access Journals (Sweden)

Alexandru BARBULESCU

2006-01-01

Full Text Available The current article points out some of the tasks and challenges companies must face in order to integrate their computerized systems and applications and then to place them on the Web. Also, the article shows how the Java 2 Enterprise Edition Platform and architecture helps the Web integration of applications. By offering standardized integration contracts, J2EE Platform allows application servers to play a key role in the process of Web integration of the applications.

SQL Server Integration Services

CERN Document Server

Hamilton, Bill

2007-01-01

SQL Server 2005 Integration Services (SSIS) lets you build high-performance data integration solutions. SSIS solutions wrap sophisticated workflows around tasks that extract, transform, and load (ETL) data from and to a wide variety of data sources. This Short Cut begins with an overview of key SSIS concepts, capabilities, standard workflow and ETL elements, the development environment, execution, deployment, and migration from Data Transformation Services (DTS). Next, you'll see how to apply the concepts you've learned through hands-on examples of common integration scenarios. Once you've

How Are Mate Preferences Linked with Actual Mate Selection? Tests of Mate Preference Integration Algorithms Using Computer Simulations and Actual Mating Couples.

Science.gov (United States)

Conroy-Beam, Daniel; Buss, David M

2016-01-01

Prior mate preference research has focused on the content of mate preferences. Yet in real life, people must select mates among potentials who vary along myriad dimensions. How do people incorporate information on many different mate preferences in order to choose which partner to pursue? Here, in Study 1, we compare seven candidate algorithms for integrating multiple mate preferences in a competitive agent-based model of human mate choice evolution. This model shows that a Euclidean algorithm is the most evolvable solution to the problem of selecting fitness-beneficial mates. Next, across three studies of actual couples (Study 2: n = 214; Study 3: n = 259; Study 4: n = 294) we apply the Euclidean algorithm toward predicting mate preference fulfillment overall and preference fulfillment as a function of mate value. Consistent with the hypothesis that mate preferences are integrated according to a Euclidean algorithm, we find that actual mates lie close in multidimensional preference space to the preferences of their partners. Moreover, this Euclidean preference fulfillment is greater for people who are higher in mate value, highlighting theoretically-predictable individual differences in who gets what they want. These new Euclidean tools have important implications for understanding real-world dynamics of mate selection.

How Are Mate Preferences Linked with Actual Mate Selection? Tests of Mate Preference Integration Algorithms Using Computer Simulations and Actual Mating Couples.

Directory of Open Access Journals (Sweden)

Daniel Conroy-Beam

Full Text Available Prior mate preference research has focused on the content of mate preferences. Yet in real life, people must select mates among potentials who vary along myriad dimensions. How do people incorporate information on many different mate preferences in order to choose which partner to pursue? Here, in Study 1, we compare seven candidate algorithms for integrating multiple mate preferences in a competitive agent-based model of human mate choice evolution. This model shows that a Euclidean algorithm is the most evolvable solution to the problem of selecting fitness-beneficial mates. Next, across three studies of actual couples (Study 2: n = 214; Study 3: n = 259; Study 4: n = 294 we apply the Euclidean algorithm toward predicting mate preference fulfillment overall and preference fulfillment as a function of mate value. Consistent with the hypothesis that mate preferences are integrated according to a Euclidean algorithm, we find that actual mates lie close in multidimensional preference space to the preferences of their partners. Moreover, this Euclidean preference fulfillment is greater for people who are higher in mate value, highlighting theoretically-predictable individual differences in who gets what they want. These new Euclidean tools have important implications for understanding real-world dynamics of mate selection.

Interrogating Key Positions of Size-Reduced TALE Repeats Reveals a Programmable Sensor of 5-Carboxylcytosine.

Science.gov (United States)

Maurer, Sara; Giess, Mario; Koch, Oliver; Summerer, Daniel

2016-12-16

Transcription-activator-like effector (TALE) proteins consist of concatenated repeats that recognize consecutive canonical nucleobases of DNA via the major groove in a programmable fashion. Since this groove displays unique chemical information for the four human epigenetic cytosine nucleobases, TALE repeats with epigenetic selectivity can be engineered, with potential to establish receptors for the programmable decoding of all human nucleobases. TALE repeats recognize nucleobases via key amino acids in a structurally conserved loop whose backbone is positioned very close to the cytosine 5-carbon. This complicates the engineering of selectivities for large 5-substituents. To interrogate a more promising structural space, we engineered size-reduced repeat loops, performed saturation mutagenesis of key positions, and screened a total of 200 repeat-nucleobase interactions for new selectivities. This provided insight into the structural requirements of TALE repeats for affinity and selectivity, revealed repeats with improved or relaxed selectivity, and resulted in the first selective sensor of 5-carboxylcytosine.

Analytic hierarchy process helps select site for limestone quarry expansion in Barbados.

Science.gov (United States)

Dey, Prasanta Kumar; Ramcharan, Eugene K

2008-09-01

Site selection is a key activity for quarry expansion to support cement production, and is governed by factors such as resource availability, logistics, costs, and socio-economic-environmental factors. Adequate consideration of all the factors facilitates both industrial productivity and sustainable economic growth. This study illustrates the site selection process that was undertaken for the expansion of limestone quarry operations to support cement production in Barbados. First, alternate sites with adequate resources to support a 25-year development horizon were identified. Second, technical and socio-economic-environmental factors were then identified. Third, a database was developed for each site with respect to each factor. Fourth, a hierarchical model in analytic hierarchy process (AHP) framework was then developed. Fifth, the relative ranking of the alternate sites was then derived through pair wise comparison in all the levels and through subsequent synthesizing of the results across the hierarchy through computer software (Expert Choice). The study reveals that an integrated framework using the AHP can help select a site for the quarry expansion project in Barbados.

The Five Key Questions of Human Performance Modeling.

Science.gov (United States)

Wu, Changxu

2018-01-01

Via building computational (typically mathematical and computer simulation) models, human performance modeling (HPM) quantifies, predicts, and maximizes human performance, human-machine system productivity and safety. This paper describes and summarizes the five key questions of human performance modeling: 1) Why we build models of human performance; 2) What the expectations of a good human performance model are; 3) What the procedures and requirements in building and verifying a human performance model are; 4) How we integrate a human performance model with system design; and 5) What the possible future directions of human performance modeling research are. Recent and classic HPM findings are addressed in the five questions to provide new thinking in HPM's motivations, expectations, procedures, system integration and future directions.

Public perceptions of key performance indicators of healthcare in Alberta, Canada.

Science.gov (United States)

Northcott, Herbert C; Harvey, Michael D

2012-06-01

To examine the relationship between public perceptions of key performance indicators assessing various aspects of the health-care system. Cross-sequential survey research. Annual telephone surveys of random samples of adult Albertans selected by random digit dialing and stratified according to age, sex and region (n = 4000 for each survey year). The survey questionnaires included single-item measures of key performance indicators to assess public perceptions of availability, accessibility, quality, outcome and satisfaction with healthcare. Cronbach's α and factor analysis were used to assess the relationship between key performance indicators focusing on the health-care system overall and on a recent interaction with the health-care system. The province of Alberta, Canada during the years 1996-2004. Four thousand adults randomly selected each survey year. Survey questions measuring public perceptions of healthcare availability, accessibility, quality, outcome and satisfaction with healthcare. Factor analysis identified two principal components with key performance indicators focusing on the health system overall loading most strongly on the first component and key performance indicators focusing on the most recent health-care encounter loading most strongly on the second component. Assessments of the quality of care most recently received, accessibility of that care and perceived outcome of care tended to be higher than the more general assessments of overall health system quality and accessibility. Assessments of specific health-care encounters and more general assessments of the overall health-care system, while related, nevertheless comprise separate dimensions for health-care evaluation.

The key to successful management of STS operations: An integrated production planning system

Science.gov (United States)

Johnson, W. A.; Thomasen, C. T.

1985-01-01

Space Transportation System operations managers are being confronted with a unique set of challenges as a result of increasing flight rates, the demand for flight manifest/production schedule flexibility and an emphasis on continued cost reduction. These challenges have created the need for an integrated production planning system that provides managers with the capability to plan, schedule, status and account for an orderly flow of products and services across a large, multi-discipline organization. With increased visibility into the end-to-end production flow for individual and parallel missions in process, managers can assess the integrated impact of changes, identify and measure the interrelationships of resource, schedule, and technical performance requirements and prioritize productivity enhancements.

INTEGRATED EDUCATION

Directory of Open Access Journals (Sweden)

Lioara-Bianca BUBOIU

2015-04-01

Full Text Available Accepting and valuing people with disabilities is a key aspect of social policies promoted worldwide. The implementation of these policies aim normalize the lives of people with disabilities through full integration in the society to which they belong. Removing discrimination and social barriers equates to a maturing of the society, maturing translated by accepting diversity that surrounds us. Each person must be appreciated at its true value regardless of its condition of normality or deviation from it. Valuing individuals can be achieved only through a full acceptance in society, by assigning statuses and fulfilling social roles. School integration of children with special educational needs in mainstream education is a challenge and involves many aspects to be successful. It is the premise of social integration, the basis for future socio-professional insertion. Integrated education is the first step towards a world of equal opportunities, a world without discrimination.

Habitat selection of endemic birds in temperate forests in a biodiversity "Hotspot"

Directory of Open Access Journals (Sweden)

Roberto A. Moreno-García

2014-08-01

Full Text Available Aim of study: Our objective was to find habitat associations at a microhabitat level for two endemic birds in a Chilean temperate forest (biodiversity “hotspots”, in order to integrate biodiversity into forest planning.Area of study: Nahuelbuta Range, Chile.Material and methods: The two birds studied were Scelorchilus rubecula (Chucao Tapaculo and Scytalopus magellanicus (Magellanic Tapaculo, both belonging to the Rhinocryptidae family. Presence or absence of the two species was sampled in 57 census spots. Habitat was categorized according to presence/absence results. We assessed the influence of abiotic variables (altitude, exposure, slope and vegetation structure (percentage of understory cover, number of strata using a statistical cluster analysis.Main results: The two bird species selected the habitat. Most frequent presence was detected at a range of 600-1100 masl, but Magellanic Tapaculo was associated to more protected sites in terms of vegetation structure (50-75% for understory cover and 2-3 strata. Slope was the most relevant abiotic variable in habitat selection due to its linkage to vegetation traits in this area.Research highlights: Our results can help managers to integrate biodiversity (endemic fauna species into forest planning by preserving certain traits of the vegetation as part of a habitat (at a microhabitat level selected by the fauna species. That planning should be implemented with both an adequate wood harvesting cuts system and specific silvicultural treatments.Key words: Chile; Nahuelbuta; rhinocryptidae; cluster analysis; rorest planning; vegetation structure.

A competitive interaction theory of attentional selection and decision making in brief, multielement displays.

Science.gov (United States)

Smith, Philip L; Sewell, David K

2013-07-01

We generalize the integrated system model of Smith and Ratcliff (2009) to obtain a new theory of attentional selection in brief, multielement visual displays. The theory proposes that attentional selection occurs via competitive interactions among detectors that signal the presence of task-relevant features at particular display locations. The outcome of the competition, together with attention, determines which stimuli are selected into visual short-term memory (VSTM). Decisions about the contents of VSTM are made by a diffusion-process decision stage. The selection process is modeled by coupled systems of shunting equations, which perform gated where-on-what pathway VSTM selection. The theory provides a computational account of key findings from attention tasks with near-threshold stimuli. These are (a) the success of the MAX model of visual search and spatial cuing, (b) the distractor homogeneity effect, (c) the double-target detection deficit, (d) redundancy costs in the post-stimulus probe task, (e) the joint item and information capacity limits of VSTM, and (f) the object-based nature of attentional selection. We argue that these phenomena are all manifestations of an underlying competitive VSTM selection process, which arise as a natural consequence of our theory. PsycINFO Database Record (c) 2013 APA, all rights reserved.

Key determinants of managing the marketing asset of global companies

Directory of Open Access Journals (Sweden)

Tatyana Tsygankova

2016-12-01

Full Text Available As a result of organization and summarization of key concepts of evolution of the marketing tools of global companies, the authors determined the role of the marketing assets in the system of modern marketing management (as a dialectically higher stage of development of the analyzed tools, which will allow overcoming the antagonistic contradiction of “P- and C-vectors” of their development. The article identified the optimal set of key elements of the system of marketing assets, which are the brand, customer loyalty, reputation, network cooperation, marketing strategy, internal marketing, marketing information system and marketing innovation. Due to correlation and regression analysis of the impact of each system elements on performance of global companies, the model of the "marketing asset octagon" was built as an integrative management tool. Also, as a result of construction of the said model, the authors identified the most profitable marketing assets, return on investment and development of competencies in the field of efficient management will bring the highest profit to the company. On the basis of summarizing the regional and branch features of managing the disparate elements of the marketing assets of global companies, the key regional and sectoral priorities of formation, development and improvement of existing concepts of the international marketing management were identified, particularly in terms of building an author’s integrative octagon model.

Indicators and measurement tools for health system integration : a knowledge synthesis protocol

OpenAIRE

Oelke, Nelly Donszelmann; Suter, Esther; Lima, Maria Alice Dias da Silva; Vliet-Brown, Cheryl Van

2015-01-01

Background: Health system integration is a key component of health system reform with the goal of improving outcomes for patients, providers, and the health system. Although health systems continue to strive for better integration, current delivery of health services continues to be fragmented. A key gap in the literature is the lack of information on what successful integration looks like and how to measure achievement towards an integrated system. This multi-site study protocol builds on a ...

Note related to the elaboration of a coding by key sentences for the programming of a document automatic selection system

International Nuclear Information System (INIS)

Leroy, A.; Braffort, P.

1959-01-01

This note deals with the providing of CEA documentalists with a tool for coding studies. The authors first discuss issues related to code selection criteria (author classification, topic classification, and so on), and propose an overview and a discussion of linguistic models. They also comment how diagrams illustrating relationships between words are built up, and propose a diagram representation example which includes different concepts such as conditions, properties, object, tools or processes (for example hardness for a steel, batch processing for a condition, or sintering for a process), and also the introduction of negation. Then, the authors address how basic concepts can be highlighted, describe how key sentences can be built up, and propose an example analysis in the case of a published article dealing with nuclear reactors (in this case, the study of a liquid-metal neutron absorber for the control of a gas-cooled power reactor). Perspectives of evolution are finally discussed

Ceftazidime Is the Key Diversification and Selection Driver of VIM-Type Carbapenemases.

Science.gov (United States)

Martínez-García, Laura; González-Alba, José M; Baquero, Fernando; Cantón, Rafael; Galán, Juan Carlos

2018-05-08

In recent decades, carbapenems have been considered the last line of antibiotic therapy for Gram-negative bacterial infections. Unfortunately, strains carrying a high diversity of β-lactamases able to hydrolyze carbapenems have emerged in the clinical setting. Among them, VIM β-lactamases have diversified in a bloom of variants. The evolutionary reconstructions performed in this work revealed that, at the end of the 1980s, two independent events involving diversification from VIM-2 and VIM-4 produced at least 25 VIM variants. Later, a third event involving diversification from VIM-1 occurred in the mid-1990s. In a second approach to understanding the emergence of VIM carbapenemases, 44 mutants derived from VIM-2 and VIM-4 were obtained by site-directed mutagenesis based on those positions predicted to be under positive selection. These variants were expressed in an isogenic context. The more-evolved variants yielded increased levels of hydrolytic efficiency toward ceftazidime to a higher degree than toward carbapenems. In fact, an antagonist effect was frequently observed. These results led us to develop an experimental-evolution step. When Escherichia coli strains carrying VIM-2 or VIM-4 were submitted to serial passages at increasing concentrations of carbapenems or ceftazidime, more-efficient new variants (such as VIM-11 and VIM-1, with N165S [bearing a change from N to S at position 165] and R228S mutations, respectively) were only obtained when ceftazidime was present. Therefore, the observed effect of ceftazidime in the diversification and selection of VIM variants might help to explain the recent bloom of carbapenemase diversity, and it also represents another example of the potential universal effect exerted by ceftazidime in the selection of more-efficient β-lactamase variants, as in TEM, CTX-M, or KPC enzymes. IMPORTANCE One of the objectives recently proposed by the World Health Organization (WHO) Assembly in the global plan on antimicrobial

Identification of key oil refining technologies for China National Petroleum Co. (CNPC)

International Nuclear Information System (INIS)

Liu Haiyan; Yu Jianning; Xu Jian; Fan Yu; Bao Xiaojun

2007-01-01

This paper summarizes the results from the project 'Vision of the Key Petroleum Refining Technologies for China National Petroleum Co. (CNPC) in the Early 21st Century' undertaken by the Department of R and D Administration, CNPC, and its affiliate key laboratory, The Key Laboratory of Catalysis operated by China University of Petroleum, Beijing. The objective of the project was to identify the challenges and opportunities of CNPC's petroleum refining business given increasing economy globalization and stricter environmental regulations. Using the modified Delphi method, four key technologies for CNPC's oil refining industry were identified. They are: integrated fluid catalytic cracking (FCC), hydroprocessing, residue hydrocracking, and high-grade lubricant production. The most significant technology will be the integrated FCC technology that can economically increase the yield of light fractions as well as upgrade transportation fuels. In China, FCC units produce about 80% and 30% commercial gasoline and diesel, respectively. To ensure compliance with future environmental legislation, hydroprocessing technologies, including those related to petroleum product hydrorefining and distillate hydrocracking, should be developed. By combining residue hydrocracking and FCC technologies, poorer quality residua can be processed. Supplying high-grade lube oils is one of the main tasks for CNPC's oil refining industry. Development of hydrodewaxing technologies to manufacture API group II/III base oil is the main direction for CNPC's lubricant production business

Key exchange using biometric identity based encryption for sharing encrypted data in cloud environment

Science.gov (United States)

Hassan, Waleed K.; Al-Assam, Hisham

2017-05-01

The main problem associated with using symmetric/ asymmetric keys is how to securely store and exchange the keys between the parties over open networks particularly in the open environment such as cloud computing. Public Key Infrastructure (PKI) have been providing a practical solution for session key exchange for loads of web services. The key limitation of PKI solution is not only the need for a trusted third partly (e.g. certificate authority) but also the absent link between data owner and the encryption keys. The latter is arguably more important where accessing data needs to be linked with identify of the owner. Currently available key exchange protocols depend on using trusted couriers or secure channels, which can be subject to man-in-the-middle attack and various other attacks. This paper proposes a new protocol for Key Exchange using Biometric Identity Based Encryption (KE-BIBE) that enables parties to securely exchange cryptographic keys even an adversary is monitoring the communication channel between the parties. The proposed protocol combines biometrics with IBE in order to provide a secure way to access symmetric keys based on the identity of the users in unsecure environment. In the KE-BIOBE protocol, the message is first encrypted by the data owner using a traditional symmetric key before migrating it to a cloud storage. The symmetric key is then encrypted using public biometrics of the users selected by data owner to decrypt the message based on Fuzzy Identity-Based Encryption. Only the selected users will be able to decrypt the message by providing a fresh sample of their biometric data. The paper argues that the proposed solution eliminates the needs for a key distribution centre in traditional cryptography. It will also give data owner the power of finegrained sharing of encrypted data by control who can access their data.

Simple Web-based interactive key development software (WEBiKEY) and an example key for Kuruna (Poaceae: Bambusoideae).

Science.gov (United States)

Attigala, Lakshmi; De Silva, Nuwan I; Clark, Lynn G

2016-04-01

Programs that are user-friendly and freely available for developing Web-based interactive keys are scarce and most of the well-structured applications are relatively expensive. WEBiKEY was developed to enable researchers to easily develop their own Web-based interactive keys with fewer resources. A Web-based multiaccess identification tool (WEBiKEY) was developed that uses freely available Microsoft ASP.NET technologies and an SQL Server database for Windows-based hosting environments. WEBiKEY was tested for its usability with a sample data set, the temperate woody bamboo genus Kuruna (Poaceae). WEBiKEY is freely available to the public and can be used to develop Web-based interactive keys for any group of species. The interactive key we developed for Kuruna using WEBiKEY enables users to visually inspect characteristics of Kuruna and identify an unknown specimen as one of seven possible species in the genus.

The University of Canberra quantum key distribution testbed

International Nuclear Information System (INIS)

Ganeshkumar, G.; Edwards, P.J.; Cheung, W.N.; Barbopoulos, L.O.; Pham, H.; Hazel, J.C.

1999-01-01

Full text: We describe the design, operation and preliminary results obtained from a quantum key distribution (QKD) testbed constructed at the University of Canberra. Quantum cryptographic systems use shared secret keys exchanged in the form of sequences of polarisation coded or phase encoded single photons transmitted over an optical communications channel. Secrecy of this quantum key rests upon fundamental laws of quantum physics: measurements of linear or circular photon polarisation states introduce noise into the conjugate variable and so reveal eavesdropping. In its initial realisation reported here, pulsed light from a 650nm laser diode is attenuated by a factor of 10 6 , plane-polarised and then transmitted through a birefringent liquid crystal modulator (LCM) to a polarisation sensitive single photon receiver. This transmitted key sequence consists of a 1 kHz train of weak coherent 100ns wide light pulses, polarisation coded according to the BB84 protocol. Each pulse is randomly assigned one of four polarisation states (two orthogonal linear and two orthogonal circular) by computer PCA operated by the sender ('Alice'). This quaternary polarisation shift keyed photon stream is detected by the receiver ('Bob') whose computer (PCB) randomly chooses either a linear or a circular polarisation basis. Computer PCB is also used for final key selection, authentication, privacy amplification and eavesdropping. We briefly discuss the realisation of a mesoscopic single photon QKD source and the use of the testbed to simulate a global quantum key distribution system using earth satellites. Copyright (1999) Australian Optical Society

Decision-Making for Supply Chain Integration Supply Chain Integration

CERN Document Server

Lettice, Fiona; Durowoju, Olatunde

2012-01-01

Effective supply chain integration, and the tight co-ordination it creates, is an essential pre-requisite for successful supply chain management.  Decision-Making for Supply Chain Integration is a practical reference on recent research in the area of supply chain integration focusing on distributed decision-making problems. Recent applications of various decision-making tools for integrating supply chains are covered including chapters focusing on: •Supplier selection, pricing strategy and inventory decisions in multi-level supply chains, •RFID-enabled distributed decision-making, •Operational risk issues and time-critical decision-making for sensitive logistics nodes, Modelling end to end processes to improve supply chain integration, and •Integrated systems to improve service delivery and optimize resource use. Decision-Making for Supply Chain Integration provides an insight into the tools and methodologies of this field with support from real-life case studies demonstrating successful application ...

A One System Integrated Approach to Simulant Selection for Hanford High Level Waste Mixing and Sampling Tests

International Nuclear Information System (INIS)

Thien, Mike G.; Barnes, Steve M.

2013-01-01

The Hanford Tank Operations Contractor (TOC) and the Hanford Waste Treatment and Immobilization Plant (WTP) contractor are both engaged in demonstrating mixing, sampling, and transfer system capabilities using simulated Hanford High-Level Waste (HLW) formulations. This represents one of the largest remaining technical issues with the high-level waste treatment mission at Hanford. Previous testing has focused on very specific TOC or WTP test objectives and consequently the simulants were narrowly focused on those test needs. A key attribute in the Defense Nuclear Facilities Safety Board (DNFSB) Recommendation 2010-2 is to ensure testing is performed with a simulant that represents the broad spectrum of Hanford waste. The One System Integrated Project Team is a new joint TOC and WTP organization intended to ensure technical integration of specific TOC and WTP systems and testing. A new approach to simulant definition has been mutually developed that will meet both TOC and WTP test objectives for the delivery and receipt of HLW. The process used to identify critical simulant characteristics, incorporate lessons learned from previous testing, and identify specific simulant targets that ensure TOC and WTP testing addresses the broad spectrum of Hanford waste characteristics that are important to mixing, sampling, and transfer performance are described

Revocable Key-Aggregate Cryptosystem for Data Sharing in Cloud

Directory of Open Access Journals (Sweden)

Qingqing Gan

2017-01-01

Full Text Available With the rapid development of network and storage technology, cloud storage has become a new service mode, while data sharing and user revocation are important functions in the cloud storage. Therefore, according to the characteristics of cloud storage, a revocable key-aggregate encryption scheme is put forward based on subset-cover framework. The proposed scheme not only has the key-aggregate characteristics, which greatly simplifies the user’s key management, but also can revoke user access permissions, realizing the flexible and effective access control. When user revocation occurs, it allows cloud server to update the ciphertext so that revoked users can not have access to the new ciphertext, while nonrevoked users do not need to update their private keys. In addition, a verification mechanism is provided in the proposed scheme, which can verify the updated ciphertext and ensure that the user revocation is performed correctly. Compared with the existing schemes, this scheme can not only reduce the cost of key management and storage, but also realize user revocation and achieve user’s access control efficiently. Finally, the proposed scheme can be proved to be selective chosen-plaintext security in the standard model.

Integrated tools for control-system analysis

Science.gov (United States)

Ostroff, Aaron J.; Proffitt, Melissa S.; Clark, David R.

1989-01-01

The basic functions embedded within a user friendly software package (MATRIXx) are used to provide a high level systems approach to the analysis of linear control systems. Various control system analysis configurations are assembled automatically to minimize the amount of work by the user. Interactive decision making is incorporated via menu options and at selected points, such as in the plotting section, by inputting data. There are five evaluations such as the singular value robustness test, singular value loop transfer frequency response, Bode frequency response, steady-state covariance analysis, and closed-loop eigenvalues. Another section describes time response simulations. A time response for random white noise disturbance is available. The configurations and key equations used for each type of analysis, the restrictions that apply, the type of data required, and an example problem are described. One approach for integrating the design and analysis tools is also presented.

Hardening Logic Encryption against Key Extraction Attacks with Circuit Camouflage

Science.gov (United States)

2017-03-01

camouflage; obfuscation; SAT; key extraction; reverse engineering ; security; trusted electronics Introduction Integrated Circuit (IC) designs are... Circuit camouflage is hardware obfuscation technology that prevents reverse engineering of a fabricated device by utilizing a relatively small...obfuscated with circuit camouflage technology, this type of attack becomes much more difficult because a reverse engineer cannot extract a gate- level

Joint-operation in water resources project in Indonesia: Integrated or non-integrated

Science.gov (United States)

Ophiyandri, Taufika; Istijono, Bambang; Hidayat, Benny

2017-11-01

The construction of large water resources infrastructure project often involved a joint-operation (JO) project between two or more construction companies. The form of JO can be grouped into two categories - an integrated type and a non-integrated type. This paper investigates the reason of forming a JO project made by companies. The specific advantages and problems of JO project is also analysed in this paper. In order to achieve the objectives, three water resources infrastructure projects were selected as case studies. Data was gathered by conducting 11 semi-structured interviews to project owners, contractor managers, and project staffs. Data was analysed by means of content analysis. It was found that the most fundamental factor to form a JO is to win a competition or tender. An integrated model is in favour because it can reduce overhead costs and has a simple management system, while a non-integrated model is selected because it can avoid a sleeping partner and make contractor more responsible for their own job.

Manet key management via Mobile Ficlke Key protocol (MFK ...

African Journals Online (AJOL)

Manet key management via Mobile Ficlke Key protocol (MFK) ... Journal of Fundamental and Applied Sciences. Journal Home · ABOUT THIS JOURNAL ... No Abstract. Keywords: MANET; key management scheme; simulation environment ...

Communicating Emotion through Haptic Design: A Study Using Physical Keys

DEFF Research Database (Denmark)

Kjellerup, Marie Kjær; Larsen, Anne Cathrine; Maier, Anja

2014-01-01

This paper explores how designers may communicate with the users of their products through haptic design. More specifically, how tactile properties of materials evoke emotions such as satisfaction, joy, or disgust. A research through design approach has been followed; mood- and material boards...... and prototypes of four ‘haptically enhanced’ (physical) keys were created. Types of keys selected include home, bicycle, hobby, and basement. An experiment with ten participants was conducted, using word association and a software to elicit product emotions (PrEmo). Results show a mapping between the designer...

Towards Automatic Decentralized Control Structure Selection

DEFF Research Database (Denmark)

for decentralized control is determined automatically, and the resulting decentralized control structure is automatically tuned using standard techniques. Dynamic simulation of the resulting process system gives immediate feedback to the process design engineer regarding practical operability of the process......A subtask in integration of design and control of chemical processes is the selection of a control structure. Automating the selection of the control structure enables sequential integration of process and controld esign. As soon as the process is specified or computed, a structure....... The control structure selection problem is formulated as a special MILP employing cost coefficients which are computed using Parseval's theorem combined with RGA and IMC concepts. This approach enables selection and tuning of large-scale plant-wide decentralized controllers through efficient combination...

Towards Automatic Decentralized Control Structure Selection

DEFF Research Database (Denmark)

Jørgensen, John Bagterp; Jørgensen, Sten Bay

2000-01-01

for decentralized control is determined automatically, and the resulting decentralized control structure is automatically tuned using standard techniques. Dynamic simulation of the resulting process system gives immediate feedback to the process design engineer regarding practical operability of the process......A subtask in integration of design and control of chemical processes is the selection of a control structure. Automating the selection of the control structure enables sequential integration of process and control design. As soon as the process is specified or computed, a structure....... The control structure selection problem is formulated as a special MILP employing cost coefficients which are computed using Parseval's theorem combined with RGA and IMC concepts. This approach enables selection and tuning of large-scale plant-wide decentralized controllers through efficient combination...

Elliptic polylogarithms and iterated integrals on elliptic curves. II. An application to the sunrise integral

Science.gov (United States)

Broedel, Johannes; Duhr, Claude; Dulat, Falko; Tancredi, Lorenzo

2018-06-01

We introduce a class of iterated integrals that generalize multiple polylogarithms to elliptic curves. These elliptic multiple polylogarithms are closely related to similar functions defined in pure mathematics and string theory. We then focus on the equal-mass and non-equal-mass sunrise integrals, and we develop a formalism that enables us to compute these Feynman integrals in terms of our iterated integrals on elliptic curves. The key idea is to use integration-by-parts identities to identify a set of integral kernels, whose precise form is determined by the branch points of the integral in question. These kernels allow us to express all iterated integrals on an elliptic curve in terms of them. The flexibility of our approach leads us to expect that it will be applicable to a large variety of integrals in high-energy physics.

An integrated computational and experimental approach to gaining selectivity for MMP-2 within the gelatinase subfamily.

Science.gov (United States)

Fabre, Benjamin; Filipiak, Kamila; Díaz, Natalia; Zapico, José María; Suárez, Dimas; Ramos, Ana; de Pascual-Teresa, Beatriz

2014-02-10

Looking for water-soluble inhibitors of matrix metalloproteinase-2 (MMP-2 or gelatinase A), we have previously reported compound 1, a potent MMP-2 inhibitor with a promising selectivity over the structurally homologous MMP-9 (gelatinase B). Here we report the results of Molecular Dynamics (MD) simulations for both gelatinases (MMP-2 and MMP-9), and for the corresponding MMP/1 complexes, in an attempt to shed light on the observed selectivity between the two enzymes. These studies indicated a higher plasticity of MMP-2 at the S1' pocket and suggested an induced-fit effect at the "back door" of this pocket. On the basis of these observations, we designed 11 a-d to aid further discrimination between MMP-2 and MMP-9. Those compounds displayed notably lower inhibitory activities against MMP-9; in particular, 11 b proved to be over 100 times more active against MMP-2 than against MMP-9. MD simulations of the MMP/11 b complexes and thermodynamic integration calculations provided structural insight and relative binding energies consistent with the experimentally observed activity data. These findings demonstrate that structural differences in the S1' pocket bottom permit an improvement in selectivity in the inhibition of MMP-2 over that of MMP-9; this is of great relevance for future structure-based drug design because MMP-2 is a validated target for cancer therapy, whereas MMP-9 plays both detrimental and protective roles in cancer. This study also supports the need to consider the dynamics of the S1' pocket in order to achieve selectivity in the inhibition of MMPs. Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Flexible riser integrity management: areas of concern and applications

Energy Technology Data Exchange (ETDEWEB)

Podskarbi, Mateusz [Schlumberger Servicos de Petroleo Ltda., Rio de Janeiro, RJ (Brazil)

2008-07-01

Flexible risers are key enables for both deep water and shallow water offshore production developments. Number of flexible risers installed worldwide is into several thousands with two main concentration areas - offshore Brazil and North Sea. Flexible risers are subject to significant loads including environmental impacts, vessel motions, internal temperature and pressure as well as substantial installation loads. Excessive loads of one type or a combination of various types of loads can cause damage to the flexible that can lead to a catastrophic failure. Industry observed number of failures increasing in recent years. Operators and manufacturing companies are taking various steps to address this issue. One of possible approaches is to use monitoring instrumentation to measure riser response and integrity in real time. This paper reviews various types of flexible riser damage mechanisms caused by impact damage, corrosion, excessive pressure, armor wire rupture, compromising flexible riser minimum bend radius, excessive fatigue loading, etc. Failure mechanisms are reviewed with particular focus on the consequences that it causes in terms of risk to the infrastructure and detectable changes. Further part of the paper is focused on monitoring techniques employed and available to detect particular types of failure mechanisms. Systematic review of the monitoring techniques is provided with specific attention given to ability of these techniques to provide early warnings of riser failure. Evaluation of monitoring techniques versus modes of operation and failure mechanism is key to selecting appropriate system that ensures effectiveness of the integrity management program. (author)

Non-resonant electromagnetic energy harvester for car-key applications

Science.gov (United States)

Li, X.; Hehn, T.; Thewes, M.; Kuehne, I.; Frey, A.; Scholl, G.; Manoli, Y.

2013-12-01

This paper presents a novel non-resonant electromagnetic energy harvester for application in a remote car-key, to extend the lifetime of the battery or even to realize a fully energy autonomous, maintenance-free car-key product. Characteristic for a car-key are low frequency and large amplitude motions during normal daily operation. The basic idea of this non-resonant generator is to use a round flat permanent magnet moving freely in a round flat cavity, which is packaged on both sides by printed circuit boards embedded with multi-layer copper coils. The primary goal of this structure is to easily integrate the energy harvester with the existing electrical circuit module into available commercial car-key designs. The whole size of the energy harvester is comparable to a CR2032 coin battery. To find out the best power-efficient and optimal design, several magnets with different dimensions and magnetizations, and various layouts of copper coils were analysed and built up for prototype testing. Experimental results show that with an axially magnetized NdFeB magnet and copper coils of design variant B a maximum open circuit voltage of 1.1V can be observed.

Practical Implementation of Various Public Key Infrastructure Models

Directory of Open Access Journals (Sweden)

Dmitriy Anatolievich Melnikov

2016-03-01

Full Text Available The paper proposes a short comparative analysis of the contemporary models of public key infrastructure (PKI and the issues of the PKI models real implementation. The Russian model of PKI is presented. Differences between the North American and West Europe models of PKI and Russian model of PKI are described. The problems of creation and main directions of further development and improvement of the Russian PKI and its integration into the global trust environment are defined.

Integration of services into workflow applications

CERN Document Server

Czarnul, Pawel

2015-01-01

Describing state-of-the-art solutions in distributed system architectures, Integration of Services into Workflow Applications presents a concise approach to the integration of loosely coupled services into workflow applications. It discusses key challenges related to the integration of distributed systems and proposes solutions, both in terms of theoretical aspects such as models and workflow scheduling algorithms, and technical solutions such as software tools and APIs.The book provides an in-depth look at workflow scheduling and proposes a way to integrate several different types of services

Multidisciplinary integration in the context of integrated care – results from the North West London Integrated Care Pilot

Directory of Open Access Journals (Sweden)

Matthew Harris

2013-10-01

Full Text Available Background: In the context of integrated care, Multidisciplinary Group (MDG meetings involve participants from diverse professional groups and organizations and are potential vehicles to advance efficiency improvements within the local health economy.  We advance a novel method to evaluate the effectiveness of MDGs by measuring the extent to which participants integrate within MDG meetings and whether this integration leads to improved working. Methods: We purposively selected four MDG meetings, and conducted a content analysis of audio-recorded and transcribed case discussions. Two coders independently coded utterances according to their ‘integrative intensity’ which was defined against three a priori independent domains – the Level (i.e. Individual, Collective and Systems; the Valence (Problem, Information and Solution; the Focus (Concrete and Abstract. Inter- and intra-rater reliability was tested with Kappa scores on one randomly selected Case Discussion.  Standardized weighted mean integration scores were calculated for Case Discussions across utterance deciles, indicating how integrative intensity changed during the conversations. Results: Twenty-three Case Discussions in four different MDG groups were transcribed and coded. Inter- and intra-rater reliability was good as shown by the Prevalence and Bias Adjusted Kappa Scores for one randomly selected Case Discussion.  There were differences in the proportion of utterances per participant type (Consultant 14.6%; Presenting GP 38.75%; Chair 7.8%; Non-Presenting GP 2.25%; Allied Health Professional 4.8%. Utterances were predominantly coded at low levels of integrative intensity; however there was a gradual increase (R2=0.66 in integrative intensity during the Case Discussions.  Based on analysis of the minutes and action points arising from the Case Discussions, this improved integration did not translate into actions moving forward. Interpretation: We characterize the MDGs as

The impact of data integrity on decision making in early lead discovery

Science.gov (United States)

Beck, Bernd; Seeliger, Daniel; Kriegl, Jan M.

2015-09-01

Data driven decision making is a key element of today's pharmaceutical research, including early drug discovery. It comprises questions like which target to pursue, which chemical series to pursue, which compound to make next, or which compound to select for advanced profiling and promotion to pre-clinical development. In the following paper we will exemplify how data integrity, i.e. the context data is generated in and auxiliary information that is provided for individual result records, can influence decision making in early lead discovery programs. In addition we will describe some approaches which we pursue at Boehringer Ingelheim to reduce the risk for getting misguided.

High Density Interconnect Microstrip Patch Antenna for 5G Base Stations with Integrated Filtering Performance

Directory of Open Access Journals (Sweden)

Marco Salucci

2018-04-01

Full Text Available The elementary radiator of a planar array for next generation millimeter-wave (mm-wave 5G base stations is described. The antenna is designed for high density interconnect (HDI manufacturing for yielding a compact, densely-interconnected, and highly-integrable stacked structure. The layout of the single element is determined by directly optimizing key radiation features of the whole planar arrangement according to specific application-driven requirements. In addition, thanks to the exploitation of a spline-shaped modelling of the radiator, suitable performance in terms of impedance matching, realized gain, half-power beamwidth (HPBW, polarization purity, and inter-element isolation are achieved within the 28-GHz pass-band. Moreover, integrated out-of-band filtering capabilities are obtained in selected and wide non-contiguous stop-bands without additional circuitry.

Intrinsically stable phase-modulated polarization encoding system for quantum key distribution

Energy Technology Data Exchange (ETDEWEB)

Liu Xiaobao [Laboratory of Photonic Information Technology, School for Information and Optoelectronic Science and Engineering, South China Normal University, Guangzhou 510006 (China); Liao Changjun [Laboratory of Photonic Information Technology, School for Information and Optoelectronic Science and Engineering, South China Normal University, Guangzhou 510006 (China)], E-mail: chliao@scnu.edu.cn; Mi Jinglong; Wang Jindong; Liu Songhao [Laboratory of Photonic Information Technology, School for Information and Optoelectronic Science and Engineering, South China Normal University, Guangzhou 510006 (China)

2008-12-22

We demonstrate experimentally an intrinsically stable polarization coding and decoding system composed of optical-fiber Sagnac interferometers with integrated phase modulators for quantum key distribution. An interference visibility of 98.35% can be kept longtime during the experiment without any efforts of active compensation for coding all four desired polarization states.

KEY FACTORS IN MARKETING FOCUSED SERVICES BUSINESSES

Directory of Open Access Journals (Sweden)

Doris Yohanna Martínez Castrillón

2016-07-01

Full Text Available This article aims to identify the key success factors in the marketing area and describe them as managerial allies for companies that wish to position themselves in the market under a good sustainable performance , for it has been consulted theoretical references of Marketing as a management partner with collection and integration of data. Methodologically, it is located within the type of descriptive research field, with a design of transactional non-experimental, with an intentional non-probabilistic stratified sample of four reporting units. The findings established fifteen (15 points of influence called "key success factors (FCE in the area of marketing, and managerial allies of service companies in the security, surveillance and protection sector in industrial, commercial and residential sectors. Finally, it is intended that the actions of marketing service companies should focus to the welfare of both the organization, such as users, both in the environment, and economic, social and technological, characterized by ethics, sustainable development and transparency to respond appropriately.

Evaluation of unique identifiers used as keys to match identical publications in Pure and SciVal

DEFF Research Database (Denmark)

Madsen, Heidi Holst; Madsen, Dicte; Gauffriau, Marianne

2016-01-01

, and erroneous optical or special character recognition. The case study explores the use of UIDs in the integration between the databases Pure and SciVal. Specifically journal publications in English are matched between the two databases. We find all error types except erroneous optical or special character......Unique identifiers (UID) are seen as an effective key to match identical publications across databases or identify duplicates in a database. The objective of the present study is to investigate how well UIDs work as match keys in the integration between Pure and SciVal, based on a case...... also briefly discuss how publication sets formed by using UIDs as the match keys may affect the bibliometric indicators number of publications, number of citations, and the average number of citations per publication. The objective is addressed in a literature review and a case study. The literature...

Key components of financial-analysis education for clinical nurses.

Science.gov (United States)

Lim, Ji Young; Noh, Wonjung

2015-09-01

In this study, we identified key components of financial-analysis education for clinical nurses. We used a literature review, focus group discussions, and a content validity index survey to develop key components of financial-analysis education. First, a wide range of references were reviewed, and 55 financial-analysis education components were gathered. Second, two focus group discussions were performed; the participants were 11 nurses who had worked for more than 3 years in a hospital, and nine components were agreed upon. Third, 12 professionals, including professors, nurse executive, nurse managers, and an accountant, participated in the content validity index. Finally, six key components of financial-analysis education were selected. These key components were as follows: understanding the need for financial analysis, introduction to financial analysis, reading and implementing balance sheets, reading and implementing income statements, understanding the concepts of financial ratios, and interpretation and practice of financial ratio analysis. The results of this study will be used to develop an education program to increase financial-management competency among clinical nurses. © 2015 Wiley Publishing Asia Pty Ltd.

Integrated Work Management: Preparer, Course 31883

Energy Technology Data Exchange (ETDEWEB)

Simpson, Lewis Edward [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2017-08-07

The preparer (also called the “planner”) plays a key role in the integrated work management (IWM) process at Los Alamos National Laboratory (LANL). This course, Integrated Work Management: Preparer (COURSE 31883), describes the IWM roles and responsibilities of the preparer. This course also discusses IWM requirements that must be met by the preparer.

Diagnosis about Integration process of youth foreign Catalan

Directory of Open Access Journals (Sweden)

Marta Sabariego Puig

2015-09-01

Full Text Available This paper presents the results of a diagnostic study on the real integration process of young migrants in Catalonia. The study was carried out using a descriptive survey of 3,830 young Catalans from varying cultural backgrounds aged between 14 and 18, with the aim of identifying the key factors influencing the integration of Catalan migrant youth. Also, in order to analyze these key elements in greater depth as factors easing and/or obstructing integration, four discussion groups were held with the same young people. Results reveal achievements and challenges for further study, useful for the design of social and educational policies which may promote the integration process, understood in its structural, social, cognitive-cultural and identitary dimensions. Our study confirms the need for a society with pluralistic beliefs, principles and actions, which should be reflected in democratic systems and social and educational policies based on the concept of integration as reciprocity.

Testing a participatory integrated assessment(PIA) approach to select climate change adaptation actions to enhance wetland sustainability: The case of Poyang Lake region in China

Institute of Scientific and Technical Information of China (English)

HUANG; Li; YIN; Yongyuan; DU; De-Bin

2015-01-01

The necessity of mainstreaming climate adaptation strategies or policies into natural resource management plans has been recognized by the UNFCCC.The IPCC AR5 report suggests a growing demand for research to provide information for a deeper and more useful understanding of climate adaptation options,and indicates a lack of effective methods to meet this increasing demand of policymakers.In this respect,a participatory integrated assessment(PIA) approach is presented in this paper to provide an effective means to mainstream wetland climate change adaptation in rural sustainable development strategies,and thus to reduce climate vulnerability and to enhance rural community livelihood.The PIA approach includes a series of research activities required to assess climate impacts on wetland ecosystems,and to prioritize adaptation responses.A range of adaptation options that address key aspects of the wetland ecosystem resilience and concerns are evaluated against community based on sustainable development indicators.The PIA approach is able to identify desirable adaptation options which can then be implemented to improve wetland ecosystem health and to enhance regional sustainable development in a changing climate.For illustration purpose,the PIA was applied in a case study in Poyang Lake(PYL) region,a critical wetland and water ecosystem in central China with important international biodiversity linkages,and a locale for key policy experiments with ecosystem rehabilitation.The PIA was used to facilitate the integration of wetland climate change adaptation in rural sustainable development actions with multi-stakeholders participation.In particular,the case shows how the PIA can be designed and implemented to select effective and practical climate change adaptation options to enhance ecosystem services management and to reduce resource use conflicts and rural poverty.Worked in partnership with multi-stakeholders and assisted with a multi-criteria decision making tool

Differential Contributions of Selective Attention and Sensory Integration to Driving Performance in Healthy Aging and Alzheimer's Disease.

Science.gov (United States)

Venkatesan, Umesh M; Festa, Elena K; Ott, Brian R; Heindel, William C

2018-05-01

Patients with Alzheimer's disease (AD) demonstrate deficits in cross-cortical feature binding distinct from age-related changes in selective attention. This may have consequences for driving performance given its demands on multisensory integration. We examined the relationship of visuospatial search and binding to driving in patients with early AD and elderly controls (EC). Participants (42 AD; 37 EC) completed search tasks requiring either luminance-motion (L-M) or color-motion (C-M) binding, analogs of within and across visual processing stream binding, respectively. Standardized road test (RIRT) and naturalistic driving data (CDAS) were collected alongside clinical screening measures. Patients performed worse than controls on most cognitive and driving indices. Visual search and clinical measures were differentially related to driving behavior across groups. L-M search and Trail Making Test (TMT-B) were associated with RIRT performance in controls, while C-M binding, TMT-B errors, and Clock Drawing correlated with CDAS performance in patients. After controlling for demographic and clinical predictors, L-M reaction time significantly predicted RIRT performance in controls. In patients, C-M binding made significant contributions to CDAS above and beyond demographic and clinical predictors. RIRT and C-M binding measures accounted for 51% of variance in CDAS performance in patients. Whereas selective attention is associated with driving behavior in EC, cross-cortical binding appears most sensitive to driving in AD. This latter relationship may emerge only in naturalistic settings, which better reflect patients' driving behavior. Visual integration may offer distinct insights into driving behavior, and thus has important implications for assessing driving competency in early AD. (JINS, 2018, 24, 486-497).

Selection of a representative subset of global climate models that captures the profile of regional changes for integrated climate impacts assessment

Directory of Open Access Journals (Sweden)

Alex C. Ruane

2017-03-01

Full Text Available Abstract We present the Representative Temperature and Precipitation (T&P GCM Subsetting Approach developed within the Agricultural Model Intercomparison and Improvement Project (AgMIP to select a practical subset of global climate models (GCMs for regional integrated assessment of climate impacts when resource limitations do not permit the full ensemble of GCMs to be evaluated given the need to also focus on impacts sector and economics models. Subsetting inherently leads to a loss of information but can free up resources to explore important uncertainties in the integrated assessment that would otherwise be prohibitive. The Representative T&P GCM Subsetting Approach identifies five individual GCMs that capture a profile of the full ensemble of temperature and precipitation change within the growing season while maintaining information about the probability that basic classes of climate changes (relatively cool/wet, cool/dry, middle, hot/wet, and hot/dry are projected in the full GCM ensemble. We demonstrate the selection methodology for maize impacts in Ames, Iowa, and discuss limitations and situations when additional information may be required to select representative GCMs. We then classify 29 GCMs over all land areas to identify regions and seasons with characteristic diagonal skewness related to surface moisture as well as extreme skewness connected to snow-albedo feedbacks and GCM uncertainty. Finally, we employ this basic approach to recognize that GCM projections demonstrate coherence across space, time, and greenhouse gas concentration pathway. The Representative T&P GCM Subsetting Approach provides a quantitative basis for the determination of useful GCM subsets, provides a practical and coherent approach where previous assessments selected solely on availability of scenarios, and may be extended for application to a range of scales and sectoral impacts.

Development of an Agent-Based Model (ABM) to Simulate the Immune System and Integration of a Regression Method to Estimate the Key ABM Parameters by Fitting the Experimental Data

Science.gov (United States)

Tong, Xuming; Chen, Jinghang; Miao, Hongyu; Li, Tingting; Zhang, Le

2015-01-01

Agent-based models (ABM) and differential equations (DE) are two commonly used methods for immune system simulation. However, it is difficult for ABM to estimate key parameters of the model by incorporating experimental data, whereas the differential equation model is incapable of describing the complicated immune system in detail. To overcome these problems, we developed an integrated ABM regression model (IABMR). It can combine the advantages of ABM and DE by employing ABM to mimic the multi-scale immune system with various phenotypes and types of cells as well as using the input and output of ABM to build up the Loess regression for key parameter estimation. Next, we employed the greedy algorithm to estimate the key parameters of the ABM with respect to the same experimental data set and used ABM to describe a 3D immune system similar to previous studies that employed the DE model. These results indicate that IABMR not only has the potential to simulate the immune system at various scales, phenotypes and cell types, but can also accurately infer the key parameters like DE model. Therefore, this study innovatively developed a complex system development mechanism that could simulate the complicated immune system in detail like ABM and validate the reliability and efficiency of model like DE by fitting the experimental data. PMID:26535589

Options of system integrated environment modelling in the predicated dynamic cyberspace

International Nuclear Information System (INIS)

Janková, Martina; Dvořák, Jiří

2015-01-01

In this article there are briefly mentioned some selected options of contemporary conception of cybernetic system models in the corresponding and possible integratable environment with modern system dynamics thinking and all this in the cyberspace of possible projecting of predicted system characteristics. The key to new capabilities of system integration modelling in the considered cyberspace is mainly the ability to improve the environment and the system integration options, all this with the aim of modern control in the hierarchically arranged dynamic cyberspace, e.g. in the currently desired electronic business with information. The aim of this article is to assess generally the trends in the use of modern modelling methods considering the cybernetics applications verified in practice, modern concept of project management and also the potential integration of artificial intelligence in the new projecting and project management of integratable and intelligent models, e.g. with the optimal structures and adaptable behaviour.The article results from the solution of a specific research partial task at the faculty; especially the moments proving that the new economics will be based more and more on information, knowledge system defined cyberspace of modern management, are stressed in the text

Options of system integrated environment modelling in the predicated dynamic cyberspace

Energy Technology Data Exchange (ETDEWEB)

Janková, Martina; Dvořák, Jiří [Institute of Informatics, Faculty of Business and Management, Brno University of Technology, Brno (Czech Republic)

2015-03-10

In this article there are briefly mentioned some selected options of contemporary conception of cybernetic system models in the corresponding and possible integratable environment with modern system dynamics thinking and all this in the cyberspace of possible projecting of predicted system characteristics. The key to new capabilities of system integration modelling in the considered cyberspace is mainly the ability to improve the environment and the system integration options, all this with the aim of modern control in the hierarchically arranged dynamic cyberspace, e.g. in the currently desired electronic business with information. The aim of this article is to assess generally the trends in the use of modern modelling methods considering the cybernetics applications verified in practice, modern concept of project management and also the potential integration of artificial intelligence in the new projecting and project management of integratable and intelligent models, e.g. with the optimal structures and adaptable behaviour.The article results from the solution of a specific research partial task at the faculty; especially the moments proving that the new economics will be based more and more on information, knowledge system defined cyberspace of modern management, are stressed in the text.

[Selective attention and schizophrenia before the administration of neuroleptics].

Science.gov (United States)

Lussier, I; Stip, E

1999-01-01

In recent years, the presence of attention deficits has been recognized as a key feature of schizophrenia. Past studies reveal that selective attention, or the ability to select relevant information while ignoring simultaneously irrelevant information, is disturbed in schizophrenic patients. According to Treisman feature-integration theory of selective attention, visual search for conjunctive targets (e.g., shape and color) requires controlled processes, that necessitate attention and operate in a serial manner. Reaction times (RTs) are therefore function of the number of stimuli in the display. When subjects are asked to detect the presence or absence of a target in an array of a variable number of stimuli, different performance patterns are expected for positive (present target) and negative trials (absent target). For positive trials, a self-terminating search is triggered, that is, the search is ended when the target is encountered. For negative trials, an exhaustive search strategy is displayed, where each stimulus is examined before the search can end; the RT slope pattern is thus double that of the positive trials. To assess the integrity of these processes, thirteen drug naive schizophrenic patients were compared to twenty normal control subjects. Neuroleptic naive patients were chosen as subjects to avoid the potential influence of medication and chronicity-related factors on performance. The subjects had to specify as fast as possible the presence or absence of the target in an array of a variable number of stimuli presented in a circular display, and comprising or not the target. Results showed that the patients can use self-terminating search strategies as well as normal control subjects. However, their ability to trigger exhaustive search strategies is impaired. Not only were patients slower than controls, but their pattern of RT results was different. These results argue in favor of an early impairment in selective attention capacities in

Quantum key distribution using continuous-variable non-Gaussian states

Science.gov (United States)

Borelli, L. F. M.; Aguiar, L. S.; Roversi, J. A.; Vidiella-Barranco, A.

2016-02-01

In this work, we present a quantum key distribution protocol using continuous-variable non-Gaussian states, homodyne detection and post-selection. The employed signal states are the photon added then subtracted coherent states (PASCS) in which one photon is added and subsequently one photon is subtracted from the field. We analyze the performance of our protocol, compared with a coherent state-based protocol, for two different attacks that could be carried out by the eavesdropper (Eve). We calculate the secret key rate transmission in a lossy line for a superior channel (beam-splitter) attack, and we show that we may increase the secret key generation rate by using the non-Gaussian PASCS rather than coherent states. We also consider the simultaneous quadrature measurement (intercept-resend) attack, and we show that the efficiency of Eve's attack is substantially reduced if PASCS are used as signal states.

Selection of a new nuclear unit for Slovakia: possibilities and key technical issues

International Nuclear Information System (INIS)

Misak, J.

2009-01-01

Plans for construction of new nuclear unit at Jaslovske Bohunice brings forward the issue of selection of reactor design. This paper compares technical characteristics (safety and operational) of pressurized water reactors that are at present available in the market, such as AP 1000 (WEC), EPR (AREVA), AES 2006 (ASE), APWR 1700 (Mitsubishi) and APR 1400 (Korea Hydro and Nuclear). Selected parameters that require close attention in future negotiations with potential suppliers are discussed in detail. Compared are parameters as type of the reactor, reactor output power, quantified level of safety, compliance with national legislature and international safety requirements, operational flexibility in meeting requirements of the grid, using of verified technology, measures for coping with severe accidents, resistance against extreme external conditions etc. (authors)

Selective and divided attention modulates auditory-vocal integration in the processing of pitch feedback errors.

Science.gov (United States)

Liu, Ying; Hu, Huijing; Jones, Jeffery A; Guo, Zhiqiang; Li, Weifeng; Chen, Xi; Liu, Peng; Liu, Hanjun

2015-08-01

Speakers rapidly adjust their ongoing vocal productions to compensate for errors they hear in their auditory feedback. It is currently unclear what role attention plays in these vocal compensations. This event-related potential (ERP) study examined the influence of selective and divided attention on the vocal and cortical responses to pitch errors heard in auditory feedback regarding ongoing vocalisations. During the production of a sustained vowel, participants briefly heard their vocal pitch shifted up two semitones while they actively attended to auditory or visual events (selective attention), or both auditory and visual events (divided attention), or were not told to attend to either modality (control condition). The behavioral results showed that attending to the pitch perturbations elicited larger vocal compensations than attending to the visual stimuli. Moreover, ERPs were likewise sensitive to the attentional manipulations: P2 responses to pitch perturbations were larger when participants attended to the auditory stimuli compared to when they attended to the visual stimuli, and compared to when they were not explicitly told to attend to either the visual or auditory stimuli. By contrast, dividing attention between the auditory and visual modalities caused suppressed P2 responses relative to all the other conditions and caused enhanced N1 responses relative to the control condition. These findings provide strong evidence for the influence of attention on the mechanisms underlying the auditory-vocal integration in the processing of pitch feedback errors. In addition, selective attention and divided attention appear to modulate the neurobehavioral processing of pitch feedback errors in different ways. © 2015 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

Adaptive Integration of Nonsmooth Dynamical Systems

Science.gov (United States)

2017-10-11

2017 W911NF-12-R-0012-03: Adaptive Integration of Nonsmooth Dynamical Systems The views, opinions and/or findings contained in this report are those of...Integration of Nonsmooth Dynamical Systems Report Term: 0-Other Email: drum@gwu.edu Distribution Statement: 1-Approved for public release; distribution is...classdrake_1_1systems_1_1_integrator_base.html ; 3) a solver for dynamical systems with arbitrary unilateral and bilateral constraints (the key component of the time stepping systems )- see

An integrated remote sensing and GIS approach for monitoring areas affected by selective logging: A case study in northern Mato Grosso, Brazilian Amazon

Science.gov (United States)

Grecchi, Rosana Cristina; Beuchle, René; Shimabukuro, Yosio Edemir; Aragão, Luiz E. O. C.; Arai, Egidio; Simonetti, Dario; Achard, Frédéric

2017-09-01

Forest cover disturbances due to processes such as logging and forest fires are a widespread issue especially in the tropics, and have heavily affected forest biomass and functioning in the Brazilian Amazon in the past decades. Satellite remote sensing has played a key role for assessing logging activities in this region; however, there are still remaining challenges regarding the quantification and monitoring of these processes affecting forested lands. In this study, we propose a new method for monitoring areas affected by selective logging in one of the hotspots of Mato Grosso state in the Brazilian Amazon, based on a combination of object-based and pixel-based classification approaches applied on remote sensing data. Logging intensity and changes over time are assessed within grid cells of 300 m × 300 m spatial resolution. Our method encompassed three main steps: (1) mapping forest/non-forest areas through an object-based classification approach applied to a temporal series of Landsat images during the period 2000-2015, (2) mapping yearly logging activities from soil fraction images on the same Landsat data series, and (3) integrating information from previous steps within a regular grid-cell of 300 m × 300 m in order to monitor disturbance intensities over this 15-years period. The overall accuracy of the baseline forest/non-forest mask (year 2000) and of the undisturbed vs disturbed forest (for selected years) were 93% and 84% respectively. Our results indicate that annual forest disturbance rates, mainly due to logging activities, were higher than annual deforestation rates during the whole period of study. The deforested areas correspond to circa 25% of the areas affected by forest disturbances. Deforestation rates were highest from 2001 to 2005 and then decreased considerably after 2006. In contrast, the annual forest disturbance rates show high temporal variability with a slow decrease over the 15-year period, resulting in a significant increase of the

An integrated remote sensing and GIS approach for monitoring areas affected by selective logging: A case study in northern Mato Grosso, Brazilian Amazon.

Science.gov (United States)

Grecchi, Rosana Cristina; Beuchle, René; Shimabukuro, Yosio Edemir; Aragão, Luiz E O C; Arai, Egidio; Simonetti, Dario; Achard, Frédéric

2017-09-01

Forest cover disturbances due to processes such as logging and forest fires are a widespread issue especially in the tropics, and have heavily affected forest biomass and functioning in the Brazilian Amazon in the past decades. Satellite remote sensing has played a key role for assessing logging activities in this region; however, there are still remaining challenges regarding the quantification and monitoring of these processes affecting forested lands. In this study, we propose a new method for monitoring areas affected by selective logging in one of the hotspots of Mato Grosso state in the Brazilian Amazon, based on a combination of object-based and pixel-based classification approaches applied on remote sensing data. Logging intensity and changes over time are assessed within grid cells of 300 m × 300 m spatial resolution. Our method encompassed three main steps: (1) mapping forest/non-forest areas through an object-based classification approach applied to a temporal series of Landsat images during the period 2000-2015, (2) mapping yearly logging activities from soil fraction images on the same Landsat data series, and (3) integrating information from previous steps within a regular grid-cell of 300 m × 300 m in order to monitor disturbance intensities over this 15-years period. The overall accuracy of the baseline forest/non-forest mask (year 2000) and of the undisturbed vs disturbed forest (for selected years) were 93% and 84% respectively. Our results indicate that annual forest disturbance rates, mainly due to logging activities, were higher than annual deforestation rates during the whole period of study. The deforested areas correspond to circa 25% of the areas affected by forest disturbances. Deforestation rates were highest from 2001 to 2005 and then decreased considerably after 2006. In contrast, the annual forest disturbance rates show high temporal variability with a slow decrease over the 15-year period, resulting in a significant increase

Recruitment and Selection of Staff - Key Components for the Reform of the Romanian Police

Directory of Open Access Journals (Sweden)

Valeria-Liliana-Amelia Purda-Nicoară (Netotea-Suciu

2011-05-01

Full Text Available Human resource management is a complex and dynamic process, whose components interrelate and reinforce one another, constantly evolving due to internal influences or because of external pressures. This is a cyclical process, and its "beginning" is represented by the recruitment and selection of staff. In the present context, when the labor market has changed so dramatically, and the demands of the employers are also ever more complex, these activities prove to be essential for the further development and success of any organization. This happens because recruitment and selection of the most suitable people result in obtaining employees who possess multiple skills and qualifications, and who are able to readily obtain high performance, an enhancement of their motivations, building a strong and lasting team, and thus ensure excellent results for the company and the ability to adapt to the present day continuous changes. Therefore, professionally addressing the Romanian Police staff recruitment and selection is absolutely necessary. If the recruitment activities will point out the most suitable people, with potential for development in the organization, a quality selection activity may be the guarantee of identifying the candidates who have the knowledge, skills and abilities needed to transform the potential capabilities into professionalism. Only organizations that will know how to build multidisciplinary, competent and motivated teams will be ready to face new challenges.

Key Features of Political Advertising as an Independent Type of Advertising Communication

Directory of Open Access Journals (Sweden)

Svetlana Anatolyevna Chubay

2015-09-01

Full Text Available To obtain the most complete understanding of the features of political advertising, the author characterizes its specific features allocated by modern researchers. The problem of defining the notion of political advertising is studied in detail. The analysis of definitions available in professional literature has allowed the author to identify a number of key features that characterize political advertising as an independent type of promotional activity. These features include belonging to the forms of mass communication, implemented through different communication channels; the presence of characteristics typical of any advertising as a form of mass communication (strategies and concepts promoting the program, ideas; an integrated approach to the selection of communication channels, means and the methods of informing the addressers that focus on the audience; the formation of psychological attitude to voting; the image nature; the manipulative potential. It is shown that the influence is the primary function of political advertising – it determines the key characteristics common to this type of advertising. Political advertising, reflecting the essence of the political platform of certain political forces, setting up voters for their support, forming and introducing into the mass consciousness a definite idea of the character of these political forces, creates the desired psychological attitude to the voting. The analysis of definitions available in professional literature has allowed the author to formulate an operational definition of political advertising, which allowed to include the features that distinguish political advertising from other forms of political communication such as political PR which is traditionally mixed with political advertising.

Integrating risks at contaminated sites

International Nuclear Information System (INIS)

MacDonell, M.; Habegger, L.; Nieves, L.; Schreiber, Z.; Travis, C.

2000-01-01

The U.S. Department of Energy (DOE) is responsible for a number of large sites across the country that were radioactively and chemically contaminated by past nuclear research, development, and production activities. Multiple risk assessments are being conducted for these sites to evaluate current conditions and determine what measures are needed to protect human health and the environment from today through the long term. Integrating the risks associated with multiple contaminants in different environmental media across extensive areas, over time periods that extend beyond 1,000 years, and for a number of different impact categories--from human health and ecological to social and economic--represents a considerable challenge. A central element of these integrated analyses is the ability to reflect key interrelationships among environmental resources and human communities that may be adversely affected by the actions or inactions being considered for a given site. Complicating the already difficult task of integrating many kinds of risk is the importance of reflecting the diverse values and preferences brought to bear by the multiple parties interested in the risk analysis process and outcome. An initial conceptual framework has been developed to provide an organized structure to this risk integration, with the aim of supporting effective environmental management decisions. This paper highlights key issues associated with comprehensive risk integration and offers suggestions developed from preliminary work at a complex DOE site

Quantum key management

Energy Technology Data Exchange (ETDEWEB)

Hughes, Richard John; Thrasher, James Thomas; Nordholt, Jane Elizabeth

2016-11-29

Innovations for quantum key management harness quantum communications to form a cryptography system within a public key infrastructure framework. In example implementations, the quantum key management innovations combine quantum key distribution and a quantum identification protocol with a Merkle signature scheme (using Winternitz one-time digital signatures or other one-time digital signatures, and Merkle hash trees) to constitute a cryptography system. More generally, the quantum key management innovations combine quantum key distribution and a quantum identification protocol with a hash-based signature scheme. This provides a secure way to identify, authenticate, verify, and exchange secret cryptographic keys. Features of the quantum key management innovations further include secure enrollment of users with a registration authority, as well as credential checking and revocation with a certificate authority, where the registration authority and/or certificate authority can be part of the same system as a trusted authority for quantum key distribution.

A selective review of selective attention research from the past century.

Science.gov (United States)

Driver, J

2001-02-01

Research on attention is concerned with selective processing of incoming sensory information. To some extent, our awareness of the world depends on what we choose to attend, not merely on the stimulation entering our senses. British psychologists have made substantial contributions to this topic in the past century. Celebrated examples include Donald Broadbent's filter theory of attention, which set the agenda for most subsequent work; and Anne Treisman's revisions of this account, and her later feature-integration theory. More recent contributions include Alan Allport's prescient emphasis on the relevance of neuroscience data, and John Duncan's integration of such data with psychological theory. An idiosyncratic but roughly chronological review of developments is presented, some practical and clinical implications are briefly sketched, and future directions suggested. One of the biggest changes in the field has been the increasing interplay between psychology and neuroscience, which promises much for the future. A related change has been the realization that selection attention is best thought of as a broad topic, encompassing a range of selective issues, rather than as a single explanatory process.

Integrated learning in practical machine element design course: a case study of V-pulley design

Science.gov (United States)

Tantrabandit, Manop

2014-06-01

To achieve an effective integrated learning in Machine Element Design course, it is of importance to bridge the basic knowledge and skills of element designs. The multiple core learning leads the pathway which consists of two main parts. The first part involves teaching documents of which the contents are number of V-groove formulae, standard of V-grooved pulleys, and parallel key dimension's formulae. The second part relates to the subjects that the students have studied prior to participating in this integrated learning course, namely Material Selection, Manufacturing Process, Applied Engineering Drawing, CAD (Computer Aided Design) animation software. Moreover, an intensive cooperation between a lecturer and students is another key factor to fulfill the success of integrated learning. Last but not least, the students need to share their knowledge within the group and among the other groups aiming to gain knowledge of and skills in 1) the application of CAD-software to build up manufacture part drawings, 2) assembly drawing, 3) simulation to verify the strength of loaded pulley by method of Finite Element Analysis (FEA), 4) the software to create animation of mounting and dismounting of a pulley to a shaft, and 5) an instruction manual. The end product of this integrated learning, as a result of the above 1 to 5 knowledge and skills obtained, the participating students can create an assembly derived from manufacture part drawings and a video presentation with bilingual (English-Thai) audio description of Vpulley with datum diameter of 250 mm, 4 grooves, and type of groove: SPA.

Key steps for integrating a basic science throughout a medical school curriculum using an e-learning approach.

Science.gov (United States)

Dubois, Eline Agnès; Franson, Kari Lanette

2009-09-01

Basic sciences can be integrated into the medical school curriculum via e-learning. The process of integrating a basic science in this manner resembles a curricular change. The change usually begins with an idea for using e-learning to teach a basic science and establishing the need for the innovation. In the planning phase, learning outcomes are formulated and a prototype of the program is developed based on the desired requirements. A realistic concept is formed after considering the limitations of the current institute. Next, a project team is assembled to develop the program and plan its integration. Incorporation of the e-learning program is facilitated by a well-developed and communicated integration plan. Various course coordinators are contacted to determine content of the e-learning program as well as establish assessment. Linking the e-learning program to existing course activities and thereby applying the basic science into the clinical context enhances the degree of integration. The success of the integration is demonstrated by a positive assessment of the program including favourable cost-benefit analysis and improved student performance. Lastly, when the program becomes institutionalised, continuously updating content and technology (when appropriate), and evaluating the integration contribute to the prolonged survival of the e-learning program.

A Time-Series Water Level Forecasting Model Based on Imputation and Variable Selection Method.

Science.gov (United States)

Yang, Jun-He; Cheng, Ching-Hsue; Chan, Chia-Pan

2017-01-01

Reservoirs are important for households and impact the national economy. This paper proposed a time-series forecasting model based on estimating a missing value followed by variable selection to forecast the reservoir's water level. This study collected data from the Taiwan Shimen Reservoir as well as daily atmospheric data from 2008 to 2015. The two datasets are concatenated into an integrated dataset based on ordering of the data as a research dataset. The proposed time-series forecasting model summarily has three foci. First, this study uses five imputation methods to directly delete the missing value. Second, we identified the key variable via factor analysis and then deleted the unimportant variables sequentially via the variable selection method. Finally, the proposed model uses a Random Forest to build the forecasting model of the reservoir's water level. This was done to compare with the listing method under the forecasting error. These experimental results indicate that the Random Forest forecasting model when applied to variable selection with full variables has better forecasting performance than the listing model. In addition, this experiment shows that the proposed variable selection can help determine five forecast methods used here to improve the forecasting capability.

Parallel Key Frame Extraction for Surveillance Video Service in a Smart City.

Science.gov (United States)

Zheng, Ran; Yao, Chuanwei; Jin, Hai; Zhu, Lei; Zhang, Qin; Deng, Wei

2015-01-01

Surveillance video service (SVS) is one of the most important services provided in a smart city. It is very important for the utilization of SVS to provide design efficient surveillance video analysis techniques. Key frame extraction is a simple yet effective technique to achieve this goal. In surveillance video applications, key frames are typically used to summarize important video content. It is very important and essential to extract key frames accurately and efficiently. A novel approach is proposed to extract key frames from traffic surveillance videos based on GPU (graphics processing units) to ensure high efficiency and accuracy. For the determination of key frames, motion is a more salient feature in presenting actions or events, especially in surveillance videos. The motion feature is extracted in GPU to reduce running time. It is also smoothed to reduce noise, and the frames with local maxima of motion information are selected as the final key frames. The experimental results show that this approach can extract key frames more accurately and efficiently compared with several other methods.

Parallel Key Frame Extraction for Surveillance Video Service in a Smart City.

Directory of Open Access Journals (Sweden)

Ran Zheng

Full Text Available Surveillance video service (SVS is one of the most important services provided in a smart city. It is very important for the utilization of SVS to provide design efficient surveillance video analysis techniques. Key frame extraction is a simple yet effective technique to achieve this goal. In surveillance video applications, key frames are typically used to summarize important video content. It is very important and essential to extract key frames accurately and efficiently. A novel approach is proposed to extract key frames from traffic surveillance videos based on GPU (graphics processing units to ensure high efficiency and accuracy. For the determination of key frames, motion is a more salient feature in presenting actions or events, especially in surveillance videos. The motion feature is extracted in GPU to reduce running time. It is also smoothed to reduce noise, and the frames with local maxima of motion information are selected as the final key frames. The experimental results show that this approach can extract key frames more accurately and efficiently compared with several other methods.

Safety analysis for key design features of KALIMER-600 design concept

International Nuclear Information System (INIS)

Lee, Yong-Bum; Kwon, Y. M.; Kim, E. K.; Suk, S. D.; Chang, W. P.; Joeng, H. Y.; Ha, K. S.; Heo, S.

2005-03-01

KAERI is developing the conceptual design of a Liquid Metal Reactor, KALIMER-600 (Korea Advanced LIquid MEtal Reactor) under the Long-term Nuclear R and D Program. KALIMER-600 addresses key issues regarding future nuclear power plants such as plant safety, economics, proliferation, and waste. In this report, key safety design features are described and safety analyses results for typical ATWS accidents, containment design basis accidents, and flow blockages in the KALIMER design are presented. First, the basic approach to achieve the safety goal and main design features of KALIMER-600 are introduced in Chapter 1, and the event categorization and acceptance criteria for the KALIMER-600 safety analysis are described in Chapter 2, In Chapter 3, results of inherent safety evaluations for the KALIMER-600 conceptual design are presented. The KALIMER-600 core and plant system are designed to assure benign performance during a selected set of events without either reactor control or protection system intervention. Safety analyses for the postulated anticipated transient without scram (ATWS) have been performed using the SSC-K code to investigate the KALIMER-600 system response to the events. The objectives of Chapter 4, are to assess the response of KALIMER-600 containment to the design basis accidents and to evaluate whether the consequences are acceptable or not in the aspect of structural integrity and the exposure dose rate. In Chapter 5, the analysis of flow blockage for KALIMER-600 with the MATRA-LMR-FB code, which has been developed for the internal flow blockage in a LMR subassembly, are described. The cases with a blockage of 6-subchannel, 24-subchannel, and 54-subchannel are analyzed

Key performance indicators in hospital based on balanced scorecard model

Directory of Open Access Journals (Sweden)

Hamed Rahimi

2017-01-01

Full Text Available Introduction: Performance measurement is receiving increasing verification all over the world. Nowadays in a lot of organizations, irrespective of their type or size, performance evaluation is the main concern and a key issue for top administrators. The purpose of this study is to organize suitable key performance indicators (KPIs for hospitals’ performance evaluation based on the balanced scorecard (BSC. Method: This is a mixed method study. In order to identify the hospital’s performance indicators (HPI, first related literature was reviewed and then the experts’ panel and Delphi method were used. In this study, two rounds were needed for the desired level of consensus. The experts rated the importance of the indicators, on a five-point Likert scale. In the consensus calculation, the consensus percentage was calculated by classifying the values 1-3 as not important (0 and 4-5 to (1 as important. Simple additive weighting technique was used to rank the indicators and select hospital’s KPIs. The data were analyzed by Excel 2010 software. Results: About 218 indicators were obtained from a review of selected literature. Through internal expert panel, 77 indicators were selected. Finally, 22 were selected for KPIs of hospitals. Ten indicators were selected in internal process perspective and 5, 4, and 3 indicators in finance, learning and growth, and customer, respectively. Conclusion: This model can be a useful tool for evaluating and comparing the performance of hospitals. However, this model is flexible and can be adjusted according to differences in the target hospitals. This study can be beneficial for hospital administrators and it can help them to change their perspective about performance evaluation.

15 CFR 921.11 - Site selection and feasibility.

Science.gov (United States)

2010-01-01

... areas (or “core area”) and a buffer zone. Key land and water areas and a buffer zone will likely require.... The term buffer zone refers to an area adjacent to or surrounding key land and water areas and essential to their integrity. Buffer zones protect the core area and provide additional protection for...

Cumulative environmental impacts and integrated coastal management: the case of Xiamen, China.

Science.gov (United States)

Xue, Xiongzhi; Hong, Huasheng; Charles, Anthony T

2004-07-01

This paper examines the assessment of cumulative environmental impacts and the implementation of integrated coastal management within the harbour of Xiamen, China, an urban region in which the coastal zone is under increasing pressure as a result of very rapid economic growth. The first stage of analysis incorporates components of a cumulative effects assessment, including (a) identification of sources of environmental impacts, notably industrial expansion, port development, shipping, waste disposal, aquaculture and coastal construction, (b) selection of a set of valued ecosystem components, focusing on circulation and siltation, water quality, sediment, the benthic community, and mangrove forests, and (c) use of a set of key indicators to examine cumulative impacts arising from the aggregate of human activities. In the second stage of analysis, the paper describes and assesses the development of an institutional framework for integrated coastal management in Xiamen, one that combines policy and planning (including legislative and enforcement mechanisms) with scientific and monitoring mechanisms (including an innovative 'marine functional zoning' system). The paper concludes that the integrated coastal management framework in Xiamen has met all relevant requirements for 'integration' as laid out in the literature, and has explicitly incorporated consideration of cumulative impacts within its management and monitoring processes.

Anomaly Monitoring Method for Key Components of Satellite

Directory of Open Access Journals (Sweden)

Jian Peng

2014-01-01

Full Text Available This paper presented a fault diagnosis method for key components of satellite, called Anomaly Monitoring Method (AMM, which is made up of state estimation based on Multivariate State Estimation Techniques (MSET and anomaly detection based on Sequential Probability Ratio Test (SPRT. On the basis of analysis failure of lithium-ion batteries (LIBs, we divided the failure of LIBs into internal failure, external failure, and thermal runaway and selected electrolyte resistance (Re and the charge transfer resistance (Rct as the key parameters of state estimation. Then, through the actual in-orbit telemetry data of the key parameters of LIBs, we obtained the actual residual value (RX and healthy residual value (RL of LIBs based on the state estimation of MSET, and then, through the residual values (RX and RL of LIBs, we detected the anomaly states based on the anomaly detection of SPRT. Lastly, we conducted an example of AMM for LIBs, and, according to the results of AMM, we validated the feasibility and effectiveness of AMM by comparing it with the results of threshold detective method (TDM.

Long distance free-space quantum key distribution

International Nuclear Information System (INIS)

Schmitt-Manderbach, T.

2007-01-01

The aim of the presented experiment was to investigate the feasibility of satellite-based global quantum key distribution. In this context, a free-space quantum key distribution experiment over a real distance of 144 km was performed. The transmitter and the receiver were situated in 2500 m altitude on the Canary Islands of La Palma and Tenerife, respectively. The small and compact transmitter unit generated attenuated laser pulses, that were sent to the receiver via a 15-cm optical telescope. The receiver unit for polarisation analysis and detection of the sent pulses was integrated into an existing mirror telescope designed for classical optical satellite communications. To ensure the required stability and efficiency of the optical link in the presence of atmospheric turbulence, the two telescopes were equipped with a bi-directional automatic tracking system. Still, due to stray light and high optical attenuation, secure key exchange would not be possible using attenuated pulses in connection with the standard BB84 protocol. The photon number statistics of attenuated pulses follows a Poissonian distribution. Hence, by removing a photon from all pulses containing two or more photons, an eavesdropper could measure its polarisation without disturbing the polarisation state of the remaining pulse. In this way, he can gain information about the key without introducing detectable errors. To protect against such attacks, the presented experiment employed the recently developed method of using additional ''decoy'' states, i.e., the the intensity of the pulses created by the transmitter were varied in a random manner. By analysing the detection probabilities of the different pulses individually, a photon-number-splitting attack can be detected. Thanks to the decoy-state analysis, the secrecy of the resulting quantum key could be ensured despite the Poissonian nature of the emitted pulses. For a channel attenuation as high as 35 dB, a secret key rate of up to 250 bit

Long distance free-space quantum key distribution

Energy Technology Data Exchange (ETDEWEB)

Schmitt-Manderbach, T.

2007-10-16

The aim of the presented experiment was to investigate the feasibility of satellite-based global quantum key distribution. In this context, a free-space quantum key distribution experiment over a real distance of 144 km was performed. The transmitter and the receiver were situated in 2500 m altitude on the Canary Islands of La Palma and Tenerife, respectively. The small and compact transmitter unit generated attenuated laser pulses, that were sent to the receiver via a 15-cm optical telescope. The receiver unit for polarisation analysis and detection of the sent pulses was integrated into an existing mirror telescope designed for classical optical satellite communications. To ensure the required stability and efficiency of the optical link in the presence of atmospheric turbulence, the two telescopes were equipped with a bi-directional automatic tracking system. Still, due to stray light and high optical attenuation, secure key exchange would not be possible using attenuated pulses in connection with the standard BB84 protocol. The photon number statistics of attenuated pulses follows a Poissonian distribution. Hence, by removing a photon from all pulses containing two or more photons, an eavesdropper could measure its polarisation without disturbing the polarisation state of the remaining pulse. In this way, he can gain information about the key without introducing detectable errors. To protect against such attacks, the presented experiment employed the recently developed method of using additional 'decoy' states, i.e., the the intensity of the pulses created by the transmitter were varied in a random manner. By analysing the detection probabilities of the different pulses individually, a photon-number-splitting attack can be detected. Thanks to the decoy-state analysis, the secrecy of the resulting quantum key could be ensured despite the Poissonian nature of the emitted pulses. For a channel attenuation as high as 35 dB, a secret key rate of up to 250

Using an Integrated Group Decision Method Based on SVM, TFN-RS-AHP, and TOPSIS-CD for Cloud Service Supplier Selection

Directory of Open Access Journals (Sweden)

Lian-hui Li

2017-01-01

Full Text Available To solve the cloud service supplier selection problem under the background of cloud computing emergence, an integrated group decision method is proposed. The cloud service supplier selection index framework is built from two perspectives of technology and technology management. Support vector machine- (SVM- based classification model is applied for the preliminary screening to reduce the number of candidate suppliers. A triangular fuzzy number-rough sets-analytic hierarchy process (TFN-RS-AHP method is designed to calculate supplier’s index value by expert’s wisdom and experience. The index weight is determined by criteria importance through intercriteria correlation (CRITIC. The suppliers are evaluated by the improved TOPSIS replacing Euclidean distance with connection distance (TOPSIS-CD. An electric power enterprise’s case is given to illustrate the correctness and feasibility of the proposed method.

Strategy and Portfolio Management Aspects of Integrated Business Planning

Directory of Open Access Journals (Sweden)

Peter Jurečka

2013-03-01

Full Text Available With ongoing globalization and thereof derived growing competitiveness on most markets, companies are under constant pressure to increase the effectiveness and efficiencies of their operations. This article focuses on one of the core business management processes – on planning, namely on Sales and Operations Planning (S&OP and its latest development stage represented by the concept of Integrated Business Planning (IBP. It aims to extend the traditional concept of S&OP for selected topics from business strategy and portfolio management, which structured inclusion into planning represent one of key factors distinguishing IBP from conventional S&OP. Implementation of IBP, which constitutes significant step towards operational excellence, is applicable for almost all business and thus can be used broadly as effective tool for facing the challenges of economic and financial crisis.

Wireless neural recording with single low-power integrated circuit.

Science.gov (United States)

Harrison, Reid R; Kier, Ryan J; Chestek, Cynthia A; Gilja, Vikash; Nuyujukian, Paul; Ryu, Stephen; Greger, Bradley; Solzbacher, Florian; Shenoy, Krishna V

2009-08-01

We present benchtop and in vivo experimental results from an integrated circuit designed for wireless implantable neural recording applications. The chip, which was fabricated in a commercially available 0.6- mum 2P3M BiCMOS process, contains 100 amplifiers, a 10-bit analog-to-digital converter (ADC), 100 threshold-based spike detectors, and a 902-928 MHz frequency-shift-keying (FSK) transmitter. Neural signals from a selected amplifier are sampled by the ADC at 15.7 kSps and telemetered over the FSK wireless data link. Power, clock, and command signals are sent to the chip wirelessly over a 2.765-MHz inductive (coil-to-coil) link. The chip is capable of operating with only two off-chip components: a power/command receiving coil and a 100-nF capacitor.

An overview of the Mixed Waste Landfill Integrated Demonstration

International Nuclear Information System (INIS)

Williams, C.V.; Burford, T.D.; Betsill, J.D.

1994-01-01

The Mixed Waste Landfill Integrated Demonstration (MWLID) focuses on ''in-situ'' characterization, monitoring, remediation, and containment of landfills in and environments that contain hazardous and mixed waste. The MWLID mission is to assess, demonstrate, and transfer technologies and systems that lead to faster, better, cheaper, and safer cleanup. Most important, the demonstrated technologies will be evaluated against the baseline of conventional technologies. Key goals of the MWLID are routine use of these technologies by Environmental Restoration Groups throughout the DOE complex and commercialization of these technologies to the private sector. The MWLID is demonstrating technologies at hazardous waste landfills located at Sandia National Laboratories and on Kirtland Air Force Base. These landfills have been selected because they are representative of many sites throughout the Southwest and in other and climates

A One System Integrated Approach to Simulant Selection for Hanford High Level Waste Mixing and Sampling Tests - 13342

Energy Technology Data Exchange (ETDEWEB)

Thien, Mike G. [Washington River Protection Solutions, LLC, P.O Box 850, Richland WA, 99352 (United States); Barnes, Steve M. [Waste Treatment Plant, 2435 Stevens Center Place, Richland WA 99354 (United States)

2013-07-01

The Hanford Tank Operations Contractor (TOC) and the Hanford Waste Treatment and Immobilization Plant (WTP) contractor are both engaged in demonstrating mixing, sampling, and transfer system capabilities using simulated Hanford High-Level Waste (HLW) formulations. This represents one of the largest remaining technical issues with the high-level waste treatment mission at Hanford. Previous testing has focused on very specific TOC or WTP test objectives and consequently the simulants were narrowly focused on those test needs. A key attribute in the Defense Nuclear Facilities Safety Board (DNFSB) Recommendation 2010-2 is to ensure testing is performed with a simulant that represents the broad spectrum of Hanford waste. The One System Integrated Project Team is a new joint TOC and WTP organization intended to ensure technical integration of specific TOC and WTP systems and testing. A new approach to simulant definition has been mutually developed that will meet both TOC and WTP test objectives for the delivery and receipt of HLW. The process used to identify critical simulant characteristics, incorporate lessons learned from previous testing, and identify specific simulant targets that ensure TOC and WTP testing addresses the broad spectrum of Hanford waste characteristics that are important to mixing, sampling, and transfer performance are described. (authors)

A One System Integrated Approach to Simulant Selection for Hanford High Level Waste Mixing and Sampling Tests - 13342

International Nuclear Information System (INIS)

Thien, Mike G.; Barnes, Steve M.

2013-01-01

The Hanford Tank Operations Contractor (TOC) and the Hanford Waste Treatment and Immobilization Plant (WTP) contractor are both engaged in demonstrating mixing, sampling, and transfer system capabilities using simulated Hanford High-Level Waste (HLW) formulations. This represents one of the largest remaining technical issues with the high-level waste treatment mission at Hanford. Previous testing has focused on very specific TOC or WTP test objectives and consequently the simulants were narrowly focused on those test needs. A key attribute in the Defense Nuclear Facilities Safety Board (DNFSB) Recommendation 2010-2 is to ensure testing is performed with a simulant that represents the broad spectrum of Hanford waste. The One System Integrated Project Team is a new joint TOC and WTP organization intended to ensure technical integration of specific TOC and WTP systems and testing. A new approach to simulant definition has been mutually developed that will meet both TOC and WTP test objectives for the delivery and receipt of HLW. The process used to identify critical simulant characteristics, incorporate lessons learned from previous testing, and identify specific simulant targets that ensure TOC and WTP testing addresses the broad spectrum of Hanford waste characteristics that are important to mixing, sampling, and transfer performance are described. (authors)

Special Issue: Selected papers from ECS'97

DEFF Research Database (Denmark)

1999-01-01

This Special Issue of Analog Integrated Circuits and Signal Processing presents extended versions of selected papers from the First Electronic Circuits and Systems Conference (ECS'97) which was held on September 4-5, 1997, in Bratislava, Slovakia.......This Special Issue of Analog Integrated Circuits and Signal Processing presents extended versions of selected papers from the First Electronic Circuits and Systems Conference (ECS'97) which was held on September 4-5, 1997, in Bratislava, Slovakia....

The selective digital integrator: A new device for modulated polarization spectroscopy

Science.gov (United States)

Vrancic, Aljosa

1998-12-01

A new device, a selective digital integrator (SDI), for the acquisition of modulated polarization spectroscopy (MPS) signals is described. Special attention is given to the accurate measurement of very small (AC component of interest 50 kHz) signals at or below noise levels. Various data acquisition methods and problems associated with the collection of modulated signals are discussed. The SDI solves most of these problems and has the following advantages: it provides the average-time resolved profile of a modulated signal; it eliminates errors if the modulation is not sinusoidal; it enables separate measurements of the various phases of the signal modulation cycle; it permits simultaneous measurement of absorption, circular dichroism (CD) and linear dichroism (LD) spectra; it facilitates 3-D absorbance measurements; it has a wide gain-switching-free dynamic range (10 orders of magnitude or more); it offers a constant S/N ratio mode of operation; it eliminates the need for photomultiplier voltage feedback, and it has faster scanning speeds. The time-resolution, selectivity, wide dynamic range, and low-overhead on-the-fly data processing are useful for other modulated spectroscopy (MS) and non-MS experiments such as pulse height distribution and time-resolved pulse counting measurements. The advantages of the MPS-SDI method are tested on the first Rydberg electronic transitions of (+)-3- methylcyclopentanone. The experimental results validate the predicted SDI capabilities. However, they also point to two difficulties that had not been noted previously: the presence of LD in a gaseous sample and a pressure- dependence of the relative peak heights of the CD spectrum. Models for these anomalies are proposed. The presence of the oscillatory LD (but not an LD background) is explained with a sample cell model based on the observed polarization-dependent time-resolved profiles of transmitted light intensity. To obtain expressions for these intensities, a theoretical

Developing a revenue integrity improvement plan.

Science.gov (United States)

Banks, Kate

2010-11-01

A revenue integrity plan should address five key areas: Accuracy of patient information. Verification of payer information and policies. Accuracy of documentation. Processing of claims. Accuracy of payment.

Information Systems Management: an Australian view of the key issues

Directory of Open Access Journals (Sweden)

Graham Pervan

1994-05-01

Full Text Available Studies investigating the key issues in IS management serve to better understand the concerns of IS managers and help to guide IS researchers in choosing IS management problems worthy of investigation. This paper presents results from a study of the key issues facing the IS managers of Australia's largest 300 organisations which is part of a three-yearly longitudinal study. In order to gain consensus on the relative importance of the key issues, a three-round Delphi method was applied. The results reveal that IS strategic planning continues to be the paramount issue in our industry, as are many issues associated with IS strategic planning, including responsiveness of the IT infrastructure, effective use of the data resource, IS for competitive advantage, and a comprehensive information architecture. A greater emphasis on quality is also revealed in highly rated issues such as effective use of the data resource, data integrity and quality assurance, and the quality of software development

Key to Language Learning Success

Directory of Open Access Journals (Sweden)

Oktavian Mantiri

2015-01-01

Full Text Available This paper looks at the important elements of language learning and teaching i.e. the role of teachers as well as the attitude and motivation of learners. Teachers undoubtedly play crucial roles in students’ language learning outcome which could ignite or diminish students’ motivation. Positive attitudes and motivation – instrumental or integrative and intrinsic or extrinsic – are key to successful learning. Therefore it is paramount for language teachers as well as learners to know these roles and nurture the best possible ways where language teaching and learning will thrive. This paper also suggested that both stake-holders should be open to holistic approach of language learning and that other factors such as the environment could play an important part in language teaching and learning success.

Theoretical Aspects of Cross-border Integration-based Economic Cooperation

Directory of Open Access Journals (Sweden)

Bilchak V.

2014-09-01

Full Text Available In this article the author analyses theoretical aspects of border economy in the conditions of modern processes of integration. The author describes the existing schools and concepts of integration stressing the role of government regulation relating to the deformations in the development of the world economic mechanism. Modern studies focus on the evolution of integration processes, which has largely affected the key elements of the world economic mechanism from classical political economy, monopoly regulation. This resulted in monopolistic competition, imperfect competition, and oligopoly – largely, through all fields and poles of economic growth to certain elements of government regulation and social reproduction on the international scale. The author examines the key elements and stages of economic integration. These stages assume a number of consecutive forms: free trade zone, customs union, common market, complete economic integration, and economic union. The article shows that the transition occurs from the lowest to the highest stages — from the processes of integration involving, firstly, trade market and then capital and labour markets to the integration of social sphere. The theoretical aspects of all these transformations can be easily traced in the case of EU integration processes.

Key Financial Metrics on Australia's Higher Education Sector--December 2016

Science.gov (United States)

Australian Government Tertiary Education Quality and Standards Agency, 2016

2016-01-01

This report is the second release of financial information held by Tertiary Education Quality and Standards Agency (TEQSA). It provides a snapshot of selected key financial metrics across the Australian higher education sector. Data in this report has been sourced from TEQSA's 2015 data collection and relates to financial years ended 31 December…

Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer