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Sample records for integrated holistic approach

  1. HOLISTIC VISION: INTEGRATIVE APPROACH IN GUIDANCE AND COUNSELING SERVICES

    Directory of Open Access Journals (Sweden)

    Ade Hidayat

    2016-06-01

    Full Text Available Abstract: The philosophical issues in Guidance and Counseling especially in epistemological discourse have made paradigmatic friction that pointed by some issues from therapeutic-clinical to comprehensive way with preventive development prespective approach. It was also caused by the wider friction where quantum physic has remove classic Newtonian one, then the influence has generally removed another disciplines, where Guidance and Counseling in one of them. Through the comprehensive paradigm, Guidance dan Counseling need to take prepare the expert in order to capable to develop integrated and comprehensive thinking awareness. It means the Guidance and Counseling holistic vision is urged. Through the holistic vision, all of the competency of student is noticed integrally, such as intellectual, emotional, social, physical, artistic, creativity, ecological awareness, and spiritual competencies.Keywords: Ecoliteracy, Holictic Vision, Guidance and Counseling of Comprehensive.

  2. BEYOND GREEN BUILDINGS: AN INTEGRATED HOLISTIC DESIGN APPROACH

    Science.gov (United States)

    Technical Challenge: The Urban Sustainable Infrastructure Engineering Program (USIEP) at the University of Colorado at Denver is designing a Sustainable Youth Zone (SYZ) building in a disadvantaged community in Commerce City, CO. The SYZ utilizes a holistic ...

  3. Integrative holistic medicine in Minnesota.

    Science.gov (United States)

    Torkelson, Carolyn J; Manahan, Bill

    2009-05-01

    Minnesota has played a leading role in the integrative holistic medicine movement in the United States for more than 2 decades. This article defines integrative holistic medicine and describes how it is practiced. It also discusses the reasons why institutions and providers here and elsewhere in the country have embraced this approach to patient care.

  4. Assessing Online Discussions: A Holistic Approach

    Science.gov (United States)

    Wang, Yu-mei; Chen, Der-Thanq

    2017-01-01

    This article reports a holistic approach to assessing online discussions. This holistic approach integrates three assessment methods: assessment of learning, assessment for learning, and assessment as learning. Assessment of learning directly examines students' learning products to decide whether they have achieved the expected learning through…

  5. Integration of distributed system simulation tools for a holistic approach to integrated building and system design

    NARCIS (Netherlands)

    Radosevic, M.; Hensen, J.L.M.; Wijsman, A.J.T.M.; Hensen, J.L.M.; Lain, M.

    2004-01-01

    Advanced architectural developments require an integrated approach to design where simulation tools available today deal. only with a small subset of the overall problem. The aim of this study is to enable run time exchange of necessary data at suitable frequency between different simulation

  6. Exploring Pedagogical Strategies to Integrate a Holistic Approach to Education into ESL Classes

    Science.gov (United States)

    Chiu, Yiching Jean

    2009-01-01

    Holistic education is a popular trend in the midst of various educational reforms, yet little systematic research has been done to consider its application in the teaching of English as a Foreign Language (EFL) and English as a Second Language (ESL) for Asian Chinese learners. According to the New Zealand Ministry of Education, holistic education…

  7. A holistic passive integrative sampling approach for assessing the presence and potential impacts of waterborne environmental contaminants

    Science.gov (United States)

    Petty, J.D.; Huckins, J.N.; Alvarez, D.A.; Brumbaugh, W. G.; Cranor, W.L.; Gale, R.W.; Rastall, A.C.; Jones-Lepp, T. L.; Leiker, T.J.; Rostad, C. E.; Furlong, E.T.

    2004-01-01

    As an integral part of our continuing research in environmental quality assessment approaches, we have developed a variety of passive integrative sampling devices widely applicable for use in defining the presence and potential impacts of a broad array of contaminants. The semipermeable membrane device has gained widespread use for sampling hydrophobic chemicals from water and air, the polar organic chemical integrative sampler is applicable for sequestering waterborne hydrophilic organic chemicals, the stabilized liquid membrane device is used to integratively sample waterborne ionic metals, and the passive integrative mercury sampler is applicable for sampling vapor phase or dissolved neutral mercury species. This suite of integrative samplers forms the basis for a new passive sampling approach for assessing the presence and potential toxicological significance of a broad spectrum of environmental contaminants. In a proof-of-concept study, three of our four passive integrative samplers were used to assess the presence of a wide variety of contaminants in the waters of a constructed wetland, and to determine the effectiveness of the constructed wetland in removing contaminants. The wetland is used for final polishing of secondary-treatment municipal wastewater and the effluent is used as a source of water for a state wildlife area. Numerous contaminants, including organochlorine pesticides, polycyclic aromatic hydrocarbons, organophosphate pesticides, and pharmaceutical chemicals (e.g., ibuprofen, oxindole, etc.) were detected in the wastewater. Herein we summarize the results of the analysis of the field-deployed samplers and demonstrate the utility of this holistic approach.

  8. Integration of the subsurface and the surface sectors for a more holistic approach for sustainable redevelopment of urban brownfields.

    Science.gov (United States)

    Norrman, Jenny; Volchko, Yevheniya; Hooimeijer, Fransje; Maring, Linda; Kain, Jaan-Henrik; Bardos, Paul; Broekx, Steven; Beames, Alistair; Rosén, Lars

    2016-09-01

    This paper presents a holistic approach to sustainable urban brownfield redevelopment where specific focus is put on the integration of a multitude of subsurface qualities in the early phases of the urban redevelopment process, i.e. in the initiative and plan phases. Achieving sustainability in brownfield redevelopment projects may be constrained by a failure of engagement between two key expert constituencies: urban planners/designers and subsurface engineers, leading to missed opportunities and unintended outcomes in the plan realisation phase. A more integrated approach delivers greater benefits. Three case studies in the Netherlands, Belgium and Sweden were used to test different sustainability assessment instruments in terms of the possibility for knowledge exchange between the subsurface and the surface sectors and in terms of cooperative learning among experts and stakeholders. Based on the lessons learned from the case studies, a generic decision process framework is suggested that supports holistic decision making. The suggested framework focuses on stakeholder involvement, communication, knowledge exchange and learning and provides an inventory of instruments that can support these processes. Copyright © 2016 Elsevier B.V. All rights reserved.

  9. Assuring the safety of genetically modified (GM) foods: the importance of an holistic, integrative approach.

    Science.gov (United States)

    Cockburn, Andrew

    2002-09-11

    Genes change continuously by natural mutation and recombination enabling man to select and breed crops having the most desirable traits such as yield or flavour. Genetic modification (GM) is a recent development which allows specific genes to be identified, isolated, copied and inserted into other plants with a high level of specificity. The food safety considerations for GM crops are basically the same as those arising from conventionally bred crops, very few of which have been subject to any testing yet are generally regarded as being safe to eat. In contrast a rigorous safety testing paradigm has been developed for GM crops, which utilises a systematic, stepwise and holistic approach. The resultant science based process, focuses on a classical evaluation of the toxic potential of the introduced novel trait and the wholesomeness of the transformed crop. In addition, detailed consideration is given to the history and safe use of the parent crop as well as that of the gene donor. The overall safety evaluation is conducted under the concept known as substantial equivalence which is enshrined in all international crop biotechnology guidelines. This provides the framework for a comparative approach to identify the similarities and differences between the GM product and its comparator which has a known history of safe use. By building a detailed profile on each step in the transformation process, from parent to new crop, and by thoroughly evaluating the significance from a safety perspective, of any differences that may be detected, a very comprehensive matrix of information is constructed which enables the conclusion as to whether the GM crop, derived food or feed is as safe as its traditional counterpart. Using this approach in the evaluation of more than 50 GM crops which have been approved worldwide, the conclusion has been that foods and feeds derived from genetically modified crops are as safe and nutritious as those derived from traditional crops. The lack of

  10. A Holistic Approach Including Biological and Geological Criteria for Integrative Management in Protected Areas.

    Science.gov (United States)

    Peña, Lorena; Monge-Ganuzas, Manu; Onaindia, Miren; De Manuel, Beatriz Fernández; Mendia, Miren

    2017-02-01

    Biodiversity hotspots and geosites are indivisible parts of natural heritage. Therefore, an adequate spatial delimitation and understanding of both and their linkages are necessary in order to be able to establish conservation policies. Normally, biodiversity hotspots are a typical target for those policies but, generally, geosites are not taken into account. Thus, this paper aims to fill this gap by providing an easily replicable method for the identification and integration of the geosites and the biodiversity hotspots in a Network for Integrative Nature Conservation that highlights their linkages. The method here presented has been applied to Urdaibai Biosphere Reserve situated in southeastern of the Bay of Biscay. The obtained results indicate that some geosites that are not directly related with biodiversity hotspots remain unprotected. Thus, from the study carried out, it can be stated that we conserving just the biodiversity hotspots is not enough to conserve the whole natural heritage of a protected area, as some plots interesting due to their relevant geoheritage remain unprotected. Therefore, it is necessary to fully integrate geosites into the planning documents of protected areas as a part of an ecosystem approach. The ecosystem approach recognizes the integrity of abiotic and biotic elements in nature conservation policies. Moreover, the proposed framework and the innovative methodology can be used as an easy input to identify priority areas for conservation, to improve the protected areas conservation planning, and to demonstrate the linkages between biodiversity hotspots and geosites.

  11. A Holistic Approach Including Biological and Geological Criteria for Integrative Management in Protected Areas

    Science.gov (United States)

    Peña, Lorena; Monge-Ganuzas, Manu; Onaindia, Miren; De Manuel, Beatriz Fernández; Mendia, Miren

    2017-02-01

    Biodiversity hotspots and geosites are indivisible parts of natural heritage. Therefore, an adequate spatial delimitation and understanding of both and their linkages are necessary in order to be able to establish conservation policies. Normally, biodiversity hotspots are a typical target for those policies but, generally, geosites are not taken into account. Thus, this paper aims to fill this gap by providing an easily replicable method for the identification and integration of the geosites and the biodiversity hotspots in a Network for Integrative Nature Conservation that highlights their linkages. The method here presented has been applied to Urdaibai Biosphere Reserve situated in southeastern of the Bay of Biscay. The obtained results indicate that some geosites that are not directly related with biodiversity hotspots remain unprotected. Thus, from the study carried out, it can be stated that we conserving just the biodiversity hotspots is not enough to conserve the whole natural heritage of a protected area, as some plots interesting due to their relevant geoheritage remain unprotected. Therefore, it is necessary to fully integrate geosites into the planning documents of protected areas as a part of an ecosystem approach. The ecosystem approach recognizes the integrity of abiotic and biotic elements in nature conservation policies. Moreover, the proposed framework and the innovative methodology can be used as an easy input to identify priority areas for conservation, to improve the protected areas conservation planning, and to demonstrate the linkages between biodiversity hotspots and geosites.

  12. A holistic approach to the integration of bicycle traffic into the urban landscape

    Directory of Open Access Journals (Sweden)

    Polonca Andrejčič Mušič

    2015-10-01

    Full Text Available Qualitative and quantitative indicators can be used to assess the quality of public space. The coherence of cycling infrastructure connectivity is an indicator of a public space's attractiveness as a basis for the quality of the bicycle traffic operation. We would like to find an optimal balance between the space's form and its image to provide good conditions for cycling as one of the most important forms of sustainable mobility, and consequently a factor facilitating a healthy lifestyle. The new approach brings a completely different view on planning cycling infrastructure, while rather than physical infrastructure characteristics, humans are placed at the forefront of the cycling infrastructure design as the most important measure of its quality. Since the complexity of human beings cannot be controlled with only one science or profession, solving the problem of bicycle traffic is not just a technical problem, but its design and management also lend a multidisciplinary character. From the perspective of different cycling infrastructure users, the study will define integrated multidisciplinary methodology for evaluating the quality of cycling infrastructure, which will equally include the criteria of sensing and perceiving of space. The new approach seeks a system of criteria, which enables the integrated planning of cycling infrastructure in all spatial, organizational, sectoral, and professional levels. All theoretical findings will be tested and demonstrated on the pilot case of the long-distance cycling connection in the area of four Slovenian coastal municipalities, namely Koper, Izola, Piran, and Ankaran.

  13. Converging Human and Malaria Vector Diagnostics with Data Management towards an Integrated Holistic One Health Approach

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    Konstantinos Mitsakakis

    2018-02-01

    Full Text Available Monitoring malaria prevalence in humans, as well as vector populations, for the presence of Plasmodium, is an integral component of effective malaria control, and eventually, elimination. In the field of human diagnostics, a major challenge is the ability to define, precisely, the causative agent of fever, thereby differentiating among several candidate (also non-malaria febrile diseases. This requires genetic-based pathogen identification and multiplexed analysis, which, in combination, are hardly provided by the current gold standard diagnostic tools. In the field of vectors, an essential component of control programs is the detection of Plasmodium species within its mosquito vectors, particularly in the salivary glands, where the infective sporozoites reside. In addition, the identification of species composition and insecticide resistance alleles within vector populations is a primary task in routine monitoring activities, aiming to support control efforts. In this context, the use of converging diagnostics is highly desirable for providing comprehensive information, including differential fever diagnosis in humans, and mosquito species composition, infection status, and resistance to insecticides of vectors. Nevertheless, the two fields of human diagnostics and vector control are rarely combined, both at the diagnostic and at the data management end, resulting in fragmented data and mis- or non-communication between various stakeholders. To this direction, molecular technologies, their integration in automated platforms, and the co-assessment of data from multiple diagnostic sources through information and communication technologies are possible pathways towards a unified human vector approach.

  14. Converging Human and Malaria Vector Diagnostics with Data Management towards an Integrated Holistic One Health Approach.

    Science.gov (United States)

    Mitsakakis, Konstantinos; Hin, Sebastian; Müller, Pie; Wipf, Nadja; Thomsen, Edward; Coleman, Michael; Zengerle, Roland; Vontas, John; Mavridis, Konstantinos

    2018-02-03

    Monitoring malaria prevalence in humans, as well as vector populations, for the presence of Plasmodium , is an integral component of effective malaria control, and eventually, elimination. In the field of human diagnostics, a major challenge is the ability to define, precisely, the causative agent of fever, thereby differentiating among several candidate (also non-malaria) febrile diseases. This requires genetic-based pathogen identification and multiplexed analysis, which, in combination, are hardly provided by the current gold standard diagnostic tools. In the field of vectors, an essential component of control programs is the detection of Plasmodium species within its mosquito vectors, particularly in the salivary glands, where the infective sporozoites reside. In addition, the identification of species composition and insecticide resistance alleles within vector populations is a primary task in routine monitoring activities, aiming to support control efforts. In this context, the use of converging diagnostics is highly desirable for providing comprehensive information, including differential fever diagnosis in humans, and mosquito species composition, infection status, and resistance to insecticides of vectors. Nevertheless, the two fields of human diagnostics and vector control are rarely combined, both at the diagnostic and at the data management end, resulting in fragmented data and mis- or non-communication between various stakeholders. To this direction, molecular technologies, their integration in automated platforms, and the co-assessment of data from multiple diagnostic sources through information and communication technologies are possible pathways towards a unified human vector approach.

  15. Converging Human and Malaria Vector Diagnostics with Data Management towards an Integrated Holistic One Health Approach

    Science.gov (United States)

    Mitsakakis, Konstantinos; Hin, Sebastian; Wipf, Nadja; Coleman, Michael; Zengerle, Roland; Vontas, John; Mavridis, Konstantinos

    2018-01-01

    Monitoring malaria prevalence in humans, as well as vector populations, for the presence of Plasmodium, is an integral component of effective malaria control, and eventually, elimination. In the field of human diagnostics, a major challenge is the ability to define, precisely, the causative agent of fever, thereby differentiating among several candidate (also non-malaria) febrile diseases. This requires genetic-based pathogen identification and multiplexed analysis, which, in combination, are hardly provided by the current gold standard diagnostic tools. In the field of vectors, an essential component of control programs is the detection of Plasmodium species within its mosquito vectors, particularly in the salivary glands, where the infective sporozoites reside. In addition, the identification of species composition and insecticide resistance alleles within vector populations is a primary task in routine monitoring activities, aiming to support control efforts. In this context, the use of converging diagnostics is highly desirable for providing comprehensive information, including differential fever diagnosis in humans, and mosquito species composition, infection status, and resistance to insecticides of vectors. Nevertheless, the two fields of human diagnostics and vector control are rarely combined, both at the diagnostic and at the data management end, resulting in fragmented data and mis- or non-communication between various stakeholders. To this direction, molecular technologies, their integration in automated platforms, and the co-assessment of data from multiple diagnostic sources through information and communication technologies are possible pathways towards a unified human vector approach. PMID:29401670

  16. Value Chain, Stakeholders Analysis and Technology: A Holistic and Integrated Approach for Determining the Cumulative Added Value of Education

    Science.gov (United States)

    Ben Khudair, Saud Abdullah; Abdalla, Abdalla Khidir

    2016-01-01

    The research problem addressed in this study focused on the students' assessment issue. Although the assessment of student learning should form part of the curriculum of school programs, many educational institutions do not make student assessment part of their teaching and learning routines. A holistic and integrated framework, which encompasses…

  17. Holistic Approach to Data Center Energy Efficiency

    Energy Technology Data Exchange (ETDEWEB)

    Hammond, Steven W [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2017-09-18

    This presentation discusses NREL's Energy System Integrations Facility and NREL's holistic design approach to sustainable data centers that led to the world's most energy-efficient data center. It describes Peregrine, a warm water liquid cooled supercomputer, waste heat reuse in the data center, demonstrated PUE and ERE, and lessons learned during four years of operation.

  18. Developing a holistic approach to obesity management.

    Science.gov (United States)

    Brown, Jenny; Wimpenny, Peter

    2011-02-01

    The aim of this paper is to discuss the theoretical background and relevance of a holistic approach to obesity management by nurses. There is a global rise in the number of people with obesity, such that it now represents one of the major health challenges. However, nurses are often influenced by physical and dietetic focused approaches and could fail to acknowledge a range of other factors that can impact on weight management. As part of the development of a holistic approach to obesity a literature search was undertaken to establish relevant theoretical perspectives that underpin practice in physical, psychological and social aspects of care (focused on the period 1995-2005). In addition, experiences of working in a secondary care weight management clinic were also drawn upon. Psychobiological, attribution and social support theories were identified that could contribute to a better understanding of obesity. If these theoretical perspectives and supporting evidence can be integrated in a holistic approach to care and management it might be possible to promote better health and well-being in those with obesity. Creating a greater understanding of the range of theoretical perspectives and supporting evidence related to obesity could, it is argued, provide enhanced care and management. © 2011 Blackwell Publishing Asia Pty Ltd.

  19. Integrated and Holistic Treatment Approach to PTSD and SUD: A Synergy

    Science.gov (United States)

    Weis, Melanie

    2010-01-01

    Individuals living with posttraumatic stress disorder (PTSD) and addiction experience a complex and dynamic interaction of symptoms from both diagnoses. However, heretofore, each diagnosis has been approached as if it were a separate treatment consideration. Therefore, an individual may be treated for either a substance use disorder (SUD) or PTSD,…

  20. Holistic and Ecological Approaches in Talent Development

    DEFF Research Database (Denmark)

    Henriksen, Kristoffer

    the somewhat opposing talent discovery and development approaches by focusing on how an environment manages the balance between these two, and how this balance becomes a part of the environment’s identity. Ecological perspectives on talent development hold rich insights for developing theories, research......Research on athletic talent has evolved from talent detection to talent development with both perspectives focusing on an individual athlete. This individual focus has been mirrored in the applied work of the sport psychology practitioner in youth competitive sport who has primarily focused...... on equipping individual athletes with the psychosocial skills required in a sport career. In contrast, the holistic ecological approach (HEA) to talent development in sport (Henriksen, Stambulova & Roessler, 2010) acknowledges the role of the overall environment in athletes’ development. The HEA integrates...

  1. A Holistic Approach to Bit Preservation

    DEFF Research Database (Denmark)

    Zierau, Eld Maj-Britt Olmütz

    2011-01-01

    This thesis presents three main results for a holistic approach to bit preservation, where the ultimate goal is to find the optimal bit preservation strategy for specific digital material that must be digitally preserved. Digital material consists of sequences of bits, where a bit is a binary digit...... which can have the value 0 or 1. Bit preservation must ensure that the bits remain intact and readable in the future, but bit preservation is not concerned with how bits can be interpreted as e.g. an image. A holistic approach to bit preservation includes aspects that influence the final choice of a bit...... a holistic approach and include aspects of digital representation, confidentiality, availability, bit safety and costs when defining requirements for the bit preservation. Analysis of such requirements and choice of the final bit preservation solution can be supported by the three main results presented...

  2. eHealth development: a holistic approach

    NARCIS (Netherlands)

    Lentferink, Aniek

    2016-01-01

    This presentation was held during the course 'eHealth development a holistic approach' at the University of Twente. The presentation included information about the project Quantified Self at Work and specifically the approach of co-creation during eHealth design with important stakeholders.

  3. Book review: Preventing Crime. A Holistic Approach.

    Directory of Open Access Journals (Sweden)

    Andrea Díaz Rozas

    2017-12-01

    Full Text Available Book review. Tore Bjørgo. Preventing Crime. A Holistic Approach. London: Palgrave Macmillan, 2016. 9781137560476 (Hb 93.59€, 9781349569786 (Pb 41.59€, 9781137560483 (eBook 76.99€.Reseña. Tore Bjørgo. Preventing Crime. A Holistic Approach. Londres: Palgrave Macmillan, 2016. 9781137560476 (Td 93.59€, 9781349569786 (Tb 41.59€, 9781137560483 (e-Libro 76.99€.DOWNLOAD THIS PAPER FROM SSRN: https://ssrn.com/abstract=3092188

  4. Advancing a holistic approach to openness

    DEFF Research Database (Denmark)

    Søndergaard, Helle Alsted; Araújo, Ana Luiza Lara de

    Open innovation has emerged as a new and interesting research area, and with this paper we wish to contribute to the research on open innovation by proposing a more holistic approach to openness that includes the internal sphere of openness. We use data from 170 Danish SMEs in the high-tech and m......Open innovation has emerged as a new and interesting research area, and with this paper we wish to contribute to the research on open innovation by proposing a more holistic approach to openness that includes the internal sphere of openness. We use data from 170 Danish SMEs in the high...

  5. A holistic approach to bit preservation

    DEFF Research Database (Denmark)

    Zierau, Eld

    2012-01-01

    Purpose: The purpose of this paper is to point out the importance of taking a holistic approach to bit preservation when setting out to find an optimal bit preservation solution for specific digital materials. In the last decade there has been an increasing awareness that bit preservation, which ...

  6. The PNEI holistic approach in coloproctology.

    Science.gov (United States)

    Pescatori, M; Podzemny, V; Pescatori, L C; Dore, M P; Bassotti, G

    2015-05-01

    The psycho-neuroendocrine-immune approach relies on the concept of considering diseases from a holistic point of view: the various components (psyche, nervous system, endocrine system, and immune system) control the diseased organ/apparatus and in turn are influenced by a feedback mechanism. In this article, we will consider the psycho-neuroendocrine-immune approach to coloproctological disorders, by providing clinical cases and discussing them in light of this approach.

  7. A comprehensive, holistic people integration process for mergers and acquisitions

    Directory of Open Access Journals (Sweden)

    Rina P. Steynberg

    2011-03-01

    Research purpose: To develop and validate a comprehensive, holistic model for the people integration process during mergers and acquisitions. Motivation for the study: The literature on a comprehensive, holistic people integration process for mergers and acquisitions is sparse and fragmented. Research design, approach and method: A qualitative approach was adopted consisting of a three step process which solicited the views of seasoned M&A Practioners; these views were compared against the available literature. Finally, practioners were asked to critique the final model from a practice perspective. The utility of the final model was assessed against two mergers and acquisitions case studies. Main findings: A comprehensive, holistic people integration process model for mergers and acquisitions was developed and validated. However, this model will only significantly enhance mergers and acquisitions value realisation if it is applied from the appropriate vantage point. Practical/managerial implications: The proposed approach will increase the probability of a successful M&A people-wise and M&A value realisation. Contribution/value add: Theoretically, the development and validation of a M&A people process integration model; practically, guidelines for successful people integration; organisationally, significantly enhancing the chances of M&A success; and community wise, the reduction of the negative effects of M&A failure on communities.

  8. [Application of holistic integrative medicine in orthodontics].

    Science.gov (United States)

    Wang, L

    2017-08-09

    Holistic integrative medicine (HIM) is a new medical knowledge system, which is formed based on the theory of HIM. HIM treats people as a whole by combining the results of basic medical research, clinical practice and clinical research during the treatment process. The concept of HIM runs through the education and treatment of orthodontics. HIM is the trending norm of both modern medicine and orthodontics. This review is about the concept of HIM and the advantages and disadvantages of specialization. Moreover, this review also discusses the vital role of HIM in orthodontic treatment and development.

  9. The use of biomarkers as integrative tools for transitional water bodies monitoring in the Water Framework Directive context - A holistic approach in Minho river transitional waters.

    Science.gov (United States)

    Capela, R; Raimundo, J; Santos, M M; Caetano, M; Micaelo, C; Vale, C; Guimarães, L; Reis-Henriques, M A

    2016-01-01

    The Water Framework Directive (WFD) provides an important legislative opportunity to promote and implement an integrated approach for the protection of inland surface waters, transitional waters, coastal waters and groundwaters. The transitional waters constitute a central piece as they are usually under high environmental pressure and by their inherent characteristics present monitoring challenges. Integrating water quality monitoring with biological monitoring can increase the cost-effectiveness of monitoring efforts. One way of doing this is with biomarkers, which effectively integrate physical-chemical status and biological quality elements, dealing holistically with adverse consequences on the health of water bodies. The new Marine Strategy Framework Directive (MSFD) already incorporates the biomarker approach. Given the recent activities of OSPAR and HELCOM to harmonize existing monitoring guidelines between MSFD and WFD the use of similar methodologies should be fostered. To illustrate the potential of the biomarker approach, juveniles of flounder (Platichthys flesus) were used to evaluate the quality of the Minho river-estuary water bodies. The use of juveniles instead of adults eliminates several confounding factors such changes on the biological responses associated with reproduction. Here, a panel of well-established biomarkers, EROD, AChE, SOD, CAT, GST, LPO, ENA and FACs (1-Hydroxyrene) were selected and measured along with a gradient of different physical conditions, and integrated with trace elements characterization on both biota and sediments. In general, a clear profile along the water bodies was found, with low seasonal and spatial variation, consistent with a low impacted area. Overall, the results support the use of both the battery of biomarkers and the use of juvenile flounders in the monitoring of the water quality status within the WFD. Copyright © 2015 Elsevier B.V. All rights reserved.

  10. Shock - A reappraisal: The holistic approach

    Directory of Open Access Journals (Sweden)

    Fabrizio Giuseppe Bonanno

    2012-01-01

    Full Text Available Shock as reaction to life-threatening condition needs to be reclassified in a timely and more scientific synopsis. It is not possible or beneficial any longer to avoid a holistic approach in critical illness. Semantics of critical illness has often been unfriendly in the literature and a simplification with the elimination of conceptual pleonasms and misnomers under the exclusive light of physiology and physiopathology would be advantageous. Speaking one language to describe the same phenomenon worldwide is essential for understanding; moreover, it increases focus on characterization and significance of the phenomena.

  11. [Personalized holistic approach to a patient with mixed leg ulcer].

    Science.gov (United States)

    Kovacević, Jadranka; Sinozić, Tamara

    2014-10-01

    Holistic approach as the philosophical orientation to care underpins the fundamental wholeness of human being and emphasizes the importance of balance within the person and between the person and his/her environment. It includes elements of the physiological, sociological, economic, psychological and spiritual dimensions, and thus providesan opportunity to assess the patient as a whole and in relation to his/ her living context. Such an integrated approach is part of the basic knowledge and skills of general practitioners/family doctors and makes them equal members of a multidisciplinary team in chronic wound patient care. In this case report on a patient with mixed leg ulcer, we will try to bring closer holistic approach in care for this kind of patients in daily practice of general practitioners/family doctors.

  12. Integration of multi-omics techniques and physiological phenotyping within a holistic phenomics approach to study senescence in model and crop plants.

    Science.gov (United States)

    Großkinsky, Dominik K; Syaifullah, Syahnada Jaya; Roitsch, Thomas

    2018-02-12

    The study of senescence in plants is complicated by diverse levels of temporal and spatial dynamics as well as the impact of external biotic and abiotic factors and crop plant management. Whereas the molecular mechanisms involved in developmentally regulated leaf senescence are very well understood, in particular in the annual model plant species Arabidopsis, senescence of other organs such as the flower, fruit, and root is much less studied as well as senescence in perennials such as trees. This review addresses the need for the integration of multi-omics techniques and physiological phenotyping into holistic phenomics approaches to dissect the complex phenomenon of senescence. That became feasible through major advances in the establishment of various, complementary 'omics' technologies. Such an interdisciplinary approach will also need to consider knowledge from the animal field, in particular in relation to novel regulators such as small, non-coding RNAs, epigenetic control and telomere length. Such a characterization of phenotypes via the acquisition of high-dimensional datasets within a systems biology approach will allow us to systematically characterize the various programmes governing senescence beyond leaf senescence in Arabidopsis and to elucidate the underlying molecular processes. Such a multi-omics approach is expected to also spur the application of results from model plants to agriculture and their verification for sustainable and environmentally friendly improvement of crop plant stress resilience and productivity and contribute to improvements based on postharvest physiology for the food industry and the benefit of its customers. © The Author(s) 2017. Published by Oxford University Press on behalf of the Society for Experimental Biology. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  13. A holistic approach to the mycetoma management.

    Science.gov (United States)

    Bakhiet, Sahar Mubarak; Fahal, Ahmed Hassan; Musa, Ahmed Mudawi; Mohamed, El Samani Wadaa; Omer, Rowa Fathelrahman; Ahmed, Eiman Siddig; El Nour, Mustafa; Mustafa, El Rayah Mohamed; Sheikh A Rahman, Manar El; Suliman, Suliman Hussein; El Mamoun, Mohamed A Gadir; El Amin, Hajo Mohamed

    2018-05-01

    Mycetoma, one of the badly neglected tropical diseases, it is a localised chronic granulomatous inflammatory disease characterised by painless subcutaneous mass and formation of multiple sinuses that produce purulent discharge and grains. If untreated early and appropriately, it usually spread to affect the deep structures and bone resulting in massive damage, deformities and disabilities. It can also spread via the lymphatics and blood leading to distant secondary satellites associated with high morbidity and mortality. To date and despite progress in mycetoma research, a huge knowledge gap remains in mycetoma pathogenesis and epidemiology resulting in the lack of objective and effective control programmes. Currently, the available disease control method is early case detection and proper management. However, the majority of patients present late with immense disease and for many of them, heroic substantial deforming surgical excisions or amputation are the only prevailing treatment options. In this communication, the Mycetoma Research Center (MRC), Sudan shares its experience in implementing a new holistic approach to manage mycetoma patients locally at the village level. The MRC in collaboration with Sennar State Ministry of Health, Sudan had established a region mycetoma centre in one of the endemic mycetoma villages in the state. The patients were treated locally in that centre, the local medical and health personals were trained on early case detection and management, the local community was trained on mycetoma advocacy, and environmental conditions improvement. This comprehensive approach had also addressed the patients' socioeconomic constraints that hinder early presentation and treatment. This approach has also included the active local health authorities, community and civil society participation and contributions to deliver the best management. This holistic approach for mycetoma patients' management proved to be effective for early case detection and

  14. A Holistic Approach to Systems Development

    Science.gov (United States)

    Wong, Douglas T.

    2008-01-01

    Introduces a Holistic and Iterative Design Process. Continuous process but can be loosely divided into four stages. More effort spent early on in the design. Human-centered and Multidisciplinary. Emphasis on Life-Cycle Cost. Extensive use of modeling, simulation, mockups, human subjects, and proven technologies. Human-centered design doesn t mean the human factors discipline is the most important Disciplines should be involved in the design: Subsystem vendors, configuration management, operations research, manufacturing engineering, simulation/modeling, cost engineering, hardware engineering, software engineering, test and evaluation, human factors, electromagnetic compatibility, integrated logistics support, reliability/maintainability/availability, safety engineering, test equipment, training systems, design-to-cost, life cycle cost, application engineering etc. 9

  15. Towards a More Holistic Stakeholder Analysis Approach

    DEFF Research Database (Denmark)

    Sedereviciute, Kristina; Valentini, Chiara

    2011-01-01

    are identified based on the dimensions of connectivity and the content shared. Accordingly, the study introduces four groups of important actors from social media: unconcerned lurkers, unconcerned influencers, concerned lurkers and concerned influencers and integrates them into the existing Stakeholder Salience...... in finding stakeholders on new environments (social media), where connectivity and relationships play a key role. The argument stems from the need to assess stakeholder presence beyond the dyadic ties. Consequently, the combination of the Stakeholder Salience Model (SSM) and social network analysis (SNA......) is proposed as a more holistic solution for stakeholder identification including those from social media. A process of finding “unknown” but important stakeholders from social media was identified incorporating the content search and the principles of SNA. Consequently, stakeholders from social media...

  16. Interventions to Support Integrated Psychological Care and Holistic Health Outcomes in Paediatrics

    OpenAIRE

    Shafran, Roz; Bennett, Sophie D.; McKenzie Smith, Mhairi

    2017-01-01

    There are strong calls from many national and international bodies for there to be a ‘holistic’ and integrated approach to the understanding and management of psychological and physical health needs. Such holistic approaches are characterized by the treatment of the whole person, taking into account mental and social factors, rather than just the symptoms of a disease. Holistic approaches can impact on mental and physical health and are cost-effective. Several psychological interventions have...

  17. Implementing an Holistic Approach in Vocational Education and Training

    Science.gov (United States)

    McGrath, Donna-Louise

    2007-01-01

    Although the phrase "holistic approach" is increasingly used in reference to vocational education and training (VET) in Australia, there appears to be a paucity of literature which extensively conceptualises or details its practical application. Existing references to an "holistic approach" appear indicative of an integrated…

  18. One Health and EcoHealth in Ontario: a qualitative study exploring how holistic and integrative approaches are shaping public health practice in Ontario.

    Science.gov (United States)

    Leung, Zee; Middleton, Dean; Morrison, Karen

    2012-05-16

    There is a growing recognition that many public health issues are complex and can be best understood by examining the relationship between human health and the health of the ecosystems in which people live. Two approaches, One Health and Ecosystem Approaches to Health (EcoHealth), can help us to better understand these intricate and complex connections, and appear to hold great promise for tackling many modern public health dilemmas. Although both One Health and EcoHealth have garnered recognition from numerous health bodies in Canada and abroad, there is still a need to better understand how these approaches are shaping the practice of public health in Ontario.The purpose of this study was to characterize how public health actors in Ontario are influenced by the holistic principles which underlie One Health and EcoHealth, and to identify important lessons from their experiences. Ten semi-structured interviews were conducted with ten participants from the public health sphere in Ontario. Participants encompassed diverse perspectives including infectious disease, food systems, urban agriculture, and environmental health. Interviews were recorded, transcribed and analyzed using qualitative content analysis to identify major themes and patterns. Four major themes emerged from the interviews: the importance of connecting human health with the environment; the role of governance in promoting these ideas; the value of partnerships and collaborations in public health practice; and the challenge of operationalizing holistic approaches to public health. Overall study participants were found to be heavily influenced by concepts couched in EcoHealth and One Health literature, despite a lack of familiarity with these fields. Although One Health and EcoHealth are lesser known approaches in the public health sphere, their holistic and systems-based principles were found to influence the thoughts, values and experiences of public health actors interviewed in this study. This

  19. Towards a Holistic Approach in EU Biomass Regulation

    NARCIS (Netherlands)

    Giljam, Renske

    The energy transition requires a legal system that promotes the most sustainable forms of energy. This requires a holistic approach that accounts for all effects of energy production throughout the energy chain. This article analyses the presence of holistic elements in the current legal framework

  20. HOLISTIC APPROACH FOR ASSESSING THE PRESENCE ...

    Science.gov (United States)

    As an integral part of our continuing research in environmental quality assessment approaches, we have developed a variety of passive integrative sampling devices widely applicable for use in defining the presence and potential impacts of a broad array of contaminants. The semipermeable membrane device (SPMD) has gained widespread use for sampling hydrophobic chemicals from water and air, the polar organic chemical integrative sampler (POCIS) is applicable for sequestering waterborne hydrophilic organic chemicals, the stabilized liquid membrane device (SLMD) is used to integratively sample waterborne ionic metals, and the passive integrative mercury sampler (PIMS) is applicable for sampling vapor phase or dissolved neutral mercury species. This suite of integrative samplers forms the basis for a new passive sampling approach for assessing the presence and potential toxicological significance of a broad spectrum of environmental contaminants. In a proof-of-concept study, three of our four passive integrative samplers were used to assess the presence o,f a wide variety of contaminants in , the waters of a constructed wetland, and to determine the effectiveness of the constructed wetland in removing contaminants. The wetland is used for fmal polishing of secondary- treatment municipal wastewater and the effluent is used as a source of water for a state wildlife area. Numerous contaminants, including organochlorine pesticides (OCs), polycyclic aromatic hydrocarbons

  1. Is there a place for a holistic approach in surgical training?

    Science.gov (United States)

    Atayoglu, Timucin; Buchholz, Noor; Atayoglu, Ayten Guner; Caliskan, Mujgan

    2014-03-01

    The holistic approach in medicine is a framework that considers and treats all aspects of a patient's needs, as it relates to their health. The goal of such an approach is to prevent illness, and to maximise the well-being of individuals and families. Holistic medicine is also referred to as integrative, which has been interpreted by some professionals as the combination of evidence-based medicine and complementary medicine. The speciality of Family Medicine (FM) is often referred to as General Practice (GP), a terminology which emphasises the holistic nature of that discipline. Furthermore, GP/FM professional bodies in some countries have incorporated the holistic and integrative approach into curricula and guidelines for doctors in training, which reflects its acceptance as a component of medical training. However, despite this validation, and despite research showing the effectiveness of such strategies in enhancing the outcomes of surgery, a holistic framework or integrative approach has not been equally integrated into speciality training for would-be surgeons. We argue that it would be advisable to include holistic approaches into surgical training and help surgeons to recognise their role in the continuum of care.

  2. Holistic Education: An Approach for 21 Century

    Science.gov (United States)

    Mahmoudi, Sirous; Jafari, Ebrahim; Nasrabadi, Hasan Ali; Liaghatdar, Mohmmd Javad

    2012-01-01

    Holistic education encompasses a wide range of philosophical orientations and pedagogical practices. Its focus is on "wholeness," and it attempts to avoid excluding any significant aspects of the human experience. It is an eclectic and inclusive movement whose main characteristic is the idea that educational experiences foster a less…

  3. A proactive and holistic information management approach is crucial ...

    African Journals Online (AJOL)

    ESARBICA Journal: Journal of the Eastern and Southern Africa Regional Branch of ... holistic information management approach is crucial to e-government development ... and to develop new electronic services hence boosting innovation.

  4. A holistic approach to marketing in Montenegrin banks

    Directory of Open Access Journals (Sweden)

    Žugić Jelena

    2016-01-01

    Full Text Available In modern conditions of market globalization and strong competition, it is necessary to improve a holistic approach to marketing in banks. This paper is based on the research conducted in the banks in Montenegro. The goal of this study was to determine whether the Montenegrin banks have clearly redefined the concept of marketing, recognized the specific nature of marketing in banking and adopted a holistic marketing concept in modern banking. The main purpose of marketing in banking is to attract, retain and develop long-term relationships with customers and other stakeholders. Also, the marketing concept in banking includes the achievement of full cooperation with customers through relationship marketing, customer relationship management (CRM, alternative distribution channels in modern banking and, in general, a holistic approach to marketing. Holistic marketing analysis will help identify the strengths and weaknesses in marketing in the banking sector of Montenegro and give platform for strategic planning for its further development.

  5. Interventions to Support Integrated Psychological Care and Holistic Health Outcomes in Paediatrics.

    Science.gov (United States)

    Shafran, Roz; Bennett, Sophie D; McKenzie Smith, Mhairi

    2017-08-16

    There are strong calls from many national and international bodies for there to be a 'holistic' and integrated approach to the understanding and management of psychological and physical health needs. Such holistic approaches are characterized by the treatment of the whole person, taking into account mental and social factors, rather than just the symptoms of a disease. Holistic approaches can impact on mental and physical health and are cost-effective. Several psychological interventions have demonstrated efficacy in improving holistic health outcomes, for example Cognitive Behaviour Therapy, Behavioural Therapies and Problem Solving Therapies. They have shown to impact upon a wide range of outcomes, including psychological distress, pain, physical health, medication adherence, and family outcomes. There is increasing recognition that the holistic goals of the child and family should be prioritised, and that interventions and outcomes should reflect these goals. A focus on holistic goals in therapy can be achieved through a combination of personalised goal-based outcomes in addition to symptom-based measures.

  6. A holistic approach to natural resource conflict

    DEFF Research Database (Denmark)

    Bond, Jennifer Lauren

    2014-01-01

    This article contributes to the field of natural resource conflict management by investigating the holistic context of a conflict case and argues against a simple resource scarcity-conflict thesis. The article takes point of departure in a pragmatic world view of conflicts in Laikipia County, Kenya...... through a likert-type questionnaire survey (N = 352), semi-structured interviews, extensive field notes and participant observation. Using an adapted version of the Unifying Negotiation Framework (UNF) to conduct an in-depth context analysis, the article shows the multitude of ecological, social...... and institutional factors which impact on the conflict complex. The critical features of the conflict from the perspective of pastoralists and farmers in Laikipia were found to be related to trust, communication, security, governance, marginalisation and violence. By conducting a thorough conflict context analysis...

  7. Holistic approaches to e-learning accessibility

    Directory of Open Access Journals (Sweden)

    Lawrie Phipps

    2006-12-01

    Full Text Available The importance of accessibility to digital e-learning resources is widely acknowledged. The World Wide Web Consortium Web Accessibility Initiative has played a leading role in promoting the importance of accessibility and developing guidelines that can help when developing accessible web resources. The accessibility of e-learning resources provides additional challenges. While it is important to consider the technical and resource related aspects of e-learning when designing and developing resources for students with disabilities, there is a need to consider pedagogic and contextual issues as well. A holistic framework is therefore proposed and described, which in addition to accessibility issues takes into account learner needs, learning outcomes, local factors, infrastructure, usability and quality assurance. The practical application and implementation of this framework is discussed and illustrated through the use of examples and case studies.

  8. Lean management beyond manufacturing a holistic approach

    CERN Document Server

    Bhasin, Sanjay

    2015-01-01

    Exploring Lean manufacturing in a holistic manner, this book helps organizations to implement Lean principles successfully by offering theoretical, empirical and practical knowledge. It empirically demonstrates how a successful Lean initiative can improve organizational efficiency, and incorporates valuable primary research to substantiate findings. It argues that Lean principles need to be applied throughout the value chain in order to be successful , and suggests that these tools need to be aligned with culture and change management. Chapters examine issues including Lean cultures, impediments to Lean, Lean and performance measurement, and the impact of Lean. Viewing Lean as a never-ending journey, this book provides a valuable resource to practising Lean managers, and specialist researchers and students, and also offers an important reference for organizations embarking on their Lean voyage.

  9. Toward a More Holistic Evaluation Approach for Rural Development

    Science.gov (United States)

    Miyoshi, Koichi

    2013-01-01

    The discussion on and development of a holistic evaluation approach for rural development will be indispensable to improving and enriching the lives of rural people. This approach can be developed by considering the conceptualization of community policy structure in rural areas, the localization of policy structure in the rural community, and the…

  10. Holistic approach to treatment of intractable central neuropathic itch.

    Science.gov (United States)

    Curtis, Ashley R; Tegeler, Charles; Burdette, Jonathan; Yosipovitch, Gil

    2011-05-01

    Central neuropathic itch can be a lifelong debilitating condition and treatment challenge. We report a patient with a traumatic brain injury with severe intractable pruritus who failed extensive pharmacologic and nonpharmacologic treatment but responded to a holistic approach using healing touch. We discuss the complexity of this type of neuropathic itch and present a holistic approach as an adjunct to therapy in reducing itch intensity. This case presentation along with the literature discussed suggests a therapeutic strategy for the management of complicated central neuropathic itch. Copyright © 2010 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.

  11. Holistic integrative medicine: toward a new era of medical advancement.

    Science.gov (United States)

    Fan, Daiming

    2017-03-01

    Medicine has encountered unprecedented problems associated with changes in nature, society, and environment, as well as with new human quests for survival, longevity, and health. In the meantime, the development of medicine is facing challenges that resulted from the over-division and specialization of disciplines and the fragmentation of medical knowledge. To construct a new medical system that is more suitable for human health and disease treatment, holistic integrative medicine (HIM), which regards the human body as a holistic entity, organically integrates the most advanced knowledge and theories in each medical field and the most effective practices in various clinical specialties to revise and adjust on the basis of social, environmental, and psychological conditions. HIM is the inevitable and necessary direction for the future development of medicine. In this article, we illustrated the connotation of HIM, the differences between HIM and other medical conceptions, and the practice of HIM in recent years.

  12. A holistic approach to pastoral care and poverty

    Directory of Open Access Journals (Sweden)

    Johan Janse van Rensburg

    2010-03-01

    Full Text Available The previous approaches to pastoral care are no longer adequate or effective for addressing the many issues related to poverty. The church has done wonderful work in terms of Christian charity. However, more needs to be done to improve the worsening situation of the poor significantly. The clear distinction between pastoral care and Christian charity is a luxury that is no longer affordable. Once we have a holistic understanding of pastoral care and counselling, we will find that we cannot possibly restrict our pastoral attention to encouraging the poor, to giving random advice and to praying. A holistic pastoral theology could lead to empowerment and should be a key concept in pastoral care with poor people and societies. The article offers a theological theory for a holistic approach and some implications of the praxis of counselling.

  13. Integration of multi-omics techniques and physiological phenotyping within a holistic phenomics approach to study senescence in model and crop plants

    Czech Academy of Sciences Publication Activity Database

    Großkinsky, D.K.; Syaifullah, S. J.; Roitsch, Thomas

    2017-01-01

    Roč. 99, č. 99 (2017), s. 1-20 ISSN 0022-0957 R&D Projects: GA MŠk(CZ) LO1415 Institutional support: RVO:67179843 Keywords : integrated approaches * multi-omics * phenomics * plant development * plant–environment interactions * plant phenotyping * plant physiology * plant senescence * senescence programme * systems biology Subject RIV: EH - Ecology, Behaviour OBOR OECD: Environmental sciences (social aspects to be 5.7) Impact factor: 5.830, year: 2016

  14. Tackling the Sustainability Dilemma: A Holistic Approach to Preparing Students for the Professional Organization

    Science.gov (United States)

    Mabry, Sibylle

    2011-01-01

    Increased knowledge of business sustainability as the basis of a holistic approach to value creation has inspired many managers to integrate ecological and social stewardship into their strategic business innovation plans. However, the coverage of sustainability issues in business courses remains small at many universities. This article…

  15. A Holistic Approach to Networked Information Systems Design and Analysis

    Science.gov (United States)

    2016-04-15

    attain quite substantial savings. 11. Optimal algorithms for energy harvesting in wireless networks. We use a Markov- decision-process (MDP) based...approach to obtain optimal policies for transmissions . The key advantage of our approach is that it holistically considers information and energy in a...Coding technique to minimize delays and the number of transmissions in Wireless Systems. As we approach an era of ubiquitous computing with information

  16. [Holistic integrative medicine: the road to the future of the development of burn medicine].

    Science.gov (United States)

    Fan, D M

    2017-01-20

    Holistic integrative medicine is the road to the future of the development of burn medicine. Not only burn medicine, but also human medicine gradually enters the era of holistic integrative medicine. Holistic integrative medicine is different from translational medicine, evidence-based medicine or precision medicine, which integrates the most advanced knowledge and theories in medicine fields with the most effective practices and experiences in clinical specialties to form a new medical system.

  17. Giuseppe Moscati (1880-1927): a holistic approach to medicine.

    Science.gov (United States)

    Ponti, Giovanni; Tomasi, Aldo

    2014-05-01

    Giuseppe Moscati was a physician, medical school professor and a pioneer in the field of biochemistry and Italian studies on diabetes. He was declared a Catholic saint in 1987. In order to respond better to both the physical and spiritual needs of his patients, he developed his own holistic approach to healthcare involving meticulous drug regimens, meditation and discipline. © The Author(s) 2013 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

  18. New business models for electric cars-A holistic approach

    International Nuclear Information System (INIS)

    Kley, Fabian; Lerch, Christian; Dallinger, David

    2011-01-01

    Climate change and global resource shortages have led to rethinking traditional individual mobility services based on combustion engines. As the consequence of technological improvements, the first electric vehicles are now being introduced and greater market penetration can be expected. But any wider implementation of battery-powered electrical propulsion systems in the future will give rise to new challenges for both the traditional automotive industry and other new players, e.g. battery manufacturers, the power supply industry and other service providers. Different application cases of electric vehicles are currently being discussed which means that numerous business models could emerge, leading to new shares in value creation and involving new players. Consequently, individual stakeholders are uncertain about which business models are really effective with regard to targeting a profitable overall concept. Therefore, this paper aims to define a holistic approach to developing business models for electric mobility, which analyzes the system as a whole on the one hand and provides decision support for affected enterprises on the other. To do so, the basic elements of electric mobility are considered and topical approaches to business models for various stakeholders are discussed. The paper concludes by presenting a systemic instrument for business models based on morphological methods. - Highlights: → We present a systemic instrument to analyze business models for electric vehicles. → Provide decision support for an enterprises dealing with electric vehicle innovations. → Combine business aspects of the triad between vehicles concepts, infrastructure as well as system integration. → In the market, activities in all domains have been initiated, but often with undefined or unclear structures.

  19. A holistic approach to recycling of CRT glass and PCBs in Vietnam

    OpenAIRE

    Wiesmeth, Hans; Häckl , Dennis; Do, Quang Trung; Bui, Duy Cam

    2012-01-01

    Rapidly growing quantities of e-waste (WEEE) demand the increasing attention of environmental policy all over the world. Developing countries are particularly affected by recycling and disposal activities, which are deemed harmful to health and environment. Holistic or integrated approaches to WEEE policy are required. The paper discusses first recycling technologies for glass from cathode ray tubes (CRT) and printed circuit boards (PCBs) in Vietnam. Thereafter the German approach to WEEE ...

  20. Holistic approach to fraud management in health insurance

    Directory of Open Access Journals (Sweden)

    Štefan Furlan

    2008-12-01

    Full Text Available Fraud present an immense problem for health insurance companies and the only way to fight fraud is by using specialized fraud management systems. The current research community focussed great efforts on different fraud detection techniques while neglecting other also important activities of fraud management. We propose a holistic approach that focuses on all 6 activities of fraud management, namely, (1 deterrence, (2 prevention, (3 detection, (4 investigation, (5 sanction and redress, and (6 monitoring. The main contribution of the paper are 15 key characteristics of a fraud management system, which enable construction of a fraud management system that provides effective and efficient support to all fraud management activities. We base our research on literature review, interviews with experts from different fields, and a case study. The case study provides additional confirmation to expert opinions, as it puts our holistic framework into practice.

  1. The Challenge of Development of a Holistic Waste Management Approach to Support the Nuclear Renaissance

    International Nuclear Information System (INIS)

    Makino, H.; Umeki, H.; Hioki, K.; McKinley, I.G.

    2009-01-01

    The recent growth of interest in atomic power, the 'nuclear renaissance', is undoubtedly driven by environmental concerns. Nevertheless, there are many opponents to such a move and, increasingly, their arguments focus on the back-end of the nuclear cycle, with waste disposal claimed to be the 'Achilles Heel' of nuclear power. It is clear that nuclear expansion - and introduction of advanced fuel cycles - will face intense scrutiny and a clear case must be made for its advantages, which will require an improved, integrated approach to waste management. Unlike the present, dispersed system that focuses only on disposal of individual waste streams, a holistic waste management approach needs to be developed for the entire back-end. In this paper, the technical challenges associated with the development of such a holistic waste management approach will be discussed in the context of recent progress in relevant technical areas, especially introduction of optimized approaches for repository design and safety assessment. (authors)

  2. [Periodontology from the perspective of holistic integrative medicine].

    Science.gov (United States)

    Luan, Q X

    2017-08-09

    Medical diciplines have been gradually differentiated and specialized during its developement, and problems due to deep specialization have been increasingly apparent. Its performance is as follows: dental specialists tends to focus on a certain narrow area and ignore neither the patients as a whole existence nor the role of the environmental factors. In this article, the author tries to show the holistic integrative medicine (HIM) from the point of view of periodontal specialty. In fact, the pathogenesis, the differential diagnosis and the treatment of periodontal diseases along with the role of preventive dentistry and basic medicine for periodontology must be considered as a whole using the philosophy of HIM. The future development of periodontal specialty should absorb the achievements of other medical and dental diciplines. Periodontist should pay more attention to HIM. The author also gives some thoughts and suggestions on how to practice HIM in the field of periodontics.

  3. Peculiarities of designing Holistic Electronic Government Services Integration Model

    Directory of Open Access Journals (Sweden)

    Tadas Limba

    2011-12-01

    Full Text Available Purpos– the aim ok this paper is to develop a Holistic Electronic Government Services Integration Model which could ensure the efficient integration of electronic government services in the local self-government level.Methodolog– the following analyses have been carried out in thirkpaper: theoretical-systematic; normative and conceptual comparative analysis of the researcha A method of modeling has also been applied.Finding– the scientific work analyzes the improvement opportunities of the models of electronic government services and their application alternatives in Lithuanian municipalities. The newly developed model of electronic government services that has been designed basng on the principle of integrating online expert consultation is primarily targeted at improvement of inside processes’ changes of an organization. Practicing the application of that model in the local self-government level starting with improvement of inside processes of an organization should help adapt more accurately and efficiently to the changing needs of the society while providing electronic government services, thus establishing a higher public value.Practical implication– the practical novelty of work is reflected not only through the integration opportunities’ assessment of the principle of online expert consultation services into the theoretical models of electronic government services that have already been developed by the scientists, but also on the basis of this principle there has been created a “Holistic Electronic Government Services Integration Model” in accordance with “E-Diamond” model basis and its practical application realization with the design of “The project of implementing the principle of online expert consultation on the model of electronic government services” for the future investigations.Originalit– the systematic, comparative analysis of the models of electronic government services carried out in the scientific

  4. [Oral maxillofacial-head and neck tumor and holistic integrative medicine].

    Science.gov (United States)

    Zhang, C P

    2017-08-09

    The advance of clinical diagnosis and treatment in oral and maxillofacial-head and neck tumors has been through the process of specialization and multidisciplinary cooperation. In most cases, a single discipline cannot meet the requirements of diagnosis and treatment, which needs the cooperation of oral and maxillofacial surgery, otolaryngology and oncology approach and therapeutic method such as surgery, radiotherapy and chemotherapy. Holistic integrative medicine aims at integrating the most effective clinical practice experience and patients' individual situation and prognosis, establishing new medical mode conforming to the modern concept and fulfilling the medical system adapting to the specific characteristics of the diseases.

  5. Integrating data infrastructure to facilitate holistic approach to the investigations of anthropogenic hazards evoked by exploration and exploitation of geo-resources

    Science.gov (United States)

    Orlecka-Sikora, Beata; Kwiatek, Grzegorz; Olszewska, Dorota; Lasocki, Stanisław; Gasparini, Paolo; Kozlovskaya, Elena; Nevalainen, Jouni; Schmittbuhl, Jean; Grasso, Jean Robert; Schaming, Marc; Biggare, Pascal; Saccarotti, Gilberto; Garcia, Alexander; Cassidy, Nigel; Toon, Sam; Mutke, Grzegorz; Sterzel, Mariusz; Szepieniec, Tomasz

    2016-04-01

    The EPOS integration plan assumes a significant contribution to the research on anthropogenic hazards (AH) associated with the exploration and exploitation of geo-resources. These problems will be dealt in Thematic Core Service "Anthropogenic Hazards" (TCS AH). TCS AH is based on the prototype built in the framework of the IS-EPOS platform project (https://tcs.ah-epos.eu/), financed from Polish structural funds (POIG.02.03.00-14-090/13-00), with will be further developed within EPOS IP project (H2020-INFRADEV-1-2015-1, INFRADEV-3-2015). TCS AH aims to have a measurable impact on innovative research and development as well as on society by providing comprehensive, wide-scale and high quality AH research infrastructure. One of the main deliverables are numerous comprehensive induced seismicity datasets called "episodes". The episode is a comprehensive data description of a geophysical process, induced or triggered by technological activity, which under certain circumstances can become hazardous for people, infrastructure and the environment. In addition to the six episodes already implemented during the mentioned IS-EPOS project, at least 20 new episodes related to conventional hydrocarbon extraction, reservoir treatment, underground mining and geothermal energy production are being integrated into the e-environment of the TCS AH. The heterogeneous multi-disciplinary data are transformed to unified structures developed within IS-EPOS project, to form integrated and validated datasets. Dedicated visualization tools for multidisciplinary data comprising episodes are also implemented. These tools are capable to aggregate and combine different data types and facilitating specific visualization possibilities (e.g. combining seismic and technological information). The implementation process, tailored for each episode, consists of four steps: (i) Data revision, determination of its accuracy and limitations; (ii) Data preparation and homogenization to follow the TCS AH

  6. A holistic approach to age estimation in refugee children.

    Science.gov (United States)

    Sypek, Scott A; Benson, Jill; Spanner, Kate A; Williams, Jan L

    2016-06-01

    Many refugee children arriving in Australia have an inaccurately documented date of birth (DOB). A medical assessment of a child's age is often requested when there is a concern that their documented DOB is incorrect. This study's aim was to assess the accuracy a holistic age assessment tool (AAT) in estimating the age of refugee children newly settled in Australia. A holistic AAT that combines medical and non-medical approaches was used to estimate the ages of 60 refugee children with a known DOB. The tool used four components to assess age: an oral narrative, developmental assessment, anthropometric measures and pubertal assessment. Assessors were blinded to the true age of the child. Correlation coefficients for the actual and estimated age were calculated for the tool overall and individual components. The correlation coefficient between the actual and estimated age from the AAT was very strong at 0.9802 (boys 0.9748, girls 0.9876). The oral narrative component of the tool performed best (R = 0.9603). Overall, 86.7% of age estimates were within 1 year of the true age. The range of differences was -1.43 to 3.92 years with a standard deviation of 0.77 years (9.24 months). The AAT is a holistic, simple and safe instrument that can be used to estimate age in refugee children with results comparable with radiological methods currently used. © 2016 Paediatrics and Child Health Division (The Royal Australasian College of Physicians).

  7. The Holistic Integrity Test (HIT - quantified resilience analysis

    Directory of Open Access Journals (Sweden)

    Dobson Mike

    2016-01-01

    Full Text Available The Holistic Integrity Test (HIT - Quantified Resilience Analysis. Rising sea levels and wider climate change mean we face an increasing risk from flooding and other natural hazards. Tough economic times make it difficult to economically justify or afford the desired level of engineered risk reduction. Add to this significant uncertainty from a range of future predictions, constantly updated with new science. We therefore need to understand not just how to reduce the risk, but what could happen should above design standard events occur. In flood terms this includes not only the direct impacts (damage and loss of life, but the wider cascade impacts to infrastructure systems and the longer term impacts on the economy and society. However, understanding the “what if” is only the first part of the equation; a range of improvement measures to mitigate such effects need to be identified and implemented. These measures should consider reducing the risk, lessening the consequences, aiding the response, and speeding up the recovery. However, they need to be objectively assessed through quantitative analysis, which underpins them technically and economically. Without such analysis, it cannot be predicted how measures will perform if the extreme events occur. It is also vital to consider all possible hazards as measures for one hazard may hinder the response to another. The Holistic Integrity Test (HIT, uses quantitative system analysis and “HITs” the site, its infrastructure, contained dangers and wider regional system to determine how it copes with a range of severe shock events, Before, During and After the event, whilst also accounting for uncertainty (as illustrated in figure 1. First explained at the TINCE 2014 Nuclear Conference in Paris, it was explained in terms of a Nuclear Facility needing to analyse the site in response to post Fukushima needs; the hit is however universally applicable. The HIT has three key risk reduction goals: The

  8. Metal chaperones: a holistic approach to the treatment of AD

    Directory of Open Access Journals (Sweden)

    Paul Anthony Adlard

    2012-03-01

    Full Text Available As the burden of proof for the role of metal ion dysregulation in the pathogenesis of multiple CNS disorders grows, it has become important to more precisely identify and differentiate the biological effects of various pharmacological modulators of metal ion homeostasis. This is particularly evident in disorders such as Alzheimer’s disease, where the use of metal chaperones (that transport metals, as opposed to chelators (which exclude metals from biological interactions, may prove to be the first truly disease modifying approach for this condition. The purpose of this mini-review is to highlight the emerging notion that metal chaperones, such as PBT2 (Prana Biotechnology, modulate a variety of critical pathways affecting key aspects of the AD cascade to provide a more holistic approach to the treatment of this disease.

  9. Taking a holistic approach to managing difficult stress fractures.

    Science.gov (United States)

    Miller, Timothy L; Best, Thomas M

    2016-09-09

    Stress fractures and other bony stress injuries occur along a spectrum of severity which can impact treatment and prognosis. When treating these injuries, it should be borne in mind that no two stress fractures behave exactly alike. Given that they are not a consistent injury, standardized treatment protocols can be challenging to develop. Treatment should be individualized to the patient or athlete, the causative activity, the anatomical site, and the severity of the injury. A holistic approach to the treatment of the most difficult stress fractures should be taken by orthopedists and sports medicine specialists. This approach is necessary to obtain optimal outcomes, minimize loss of fitness and time away from sports participation, and decrease the risk of recurrence.

  10. Holistic Considerations in Optimizing a Sterile Product Package to Ensure Container Closure Integrity.

    Science.gov (United States)

    Degrazio, Fran L

    2018-01-01

    A new major chapter dealing with container closure integrity was released by the United States Pharmacopeial Convention. Chapter provides a significant amount of education and guidance concerning test methodologies to prove that a system is integral and safe for use. The test method used is only one of the major considerations in approaching the challenge of proving an integral system. This paper takes a holistic review of all the major considerations needed in qualifying a new vial system for container closure integrity. There is substantial interplay among many aspects in the process of sealing a vial. This review helps to define major risks that need to be considered and mitigated and reinforces the need to understand the maximum allowable leakage limit that is acceptable for a specific drug application. A typical risk-based approach considers materials, test methods, process, people, environment, and equipment. Each of these aspects is considered in some detail along with a recommended process flow for building a best practice, science-based approach. This approach will inform decision making for evaluating the correct combination of components and assuring they are assembled and tested in an appropriate manner. This work, once completed, can be the basis for a vial system platform or specific drug application qualification. LAY ABSTRACT: Container closure integrity is a fundamental requirement of every sterile drug package. With recent upgrading of compendia standards and guidance around this issue, there is an opportunity to better define a best practice approach to a complicated subject. It is important to recognize that there is substantial interplay among the components of the system, the process of assembly, and the test methods that are used. This paper takes a holistic approach to discussing these issues and identifying the risks that must be considered in assuring an integral container over the shelf life of a drug product. © PDA, Inc. 2018.

  11. A holistic approach to factors affecting depression in haemodialysis patients.

    Science.gov (United States)

    Gerogianni, Georgia; Kouzoupis, Anastasios; Grapsa, Eirini

    2018-05-19

    Depression in dialysis populations is affected by co-morbid diseases, such as cardiovascular disease, diabetes, and immune dysfunction, and it also includes high suicide risk and frequent hospitalizations. Depressive disorders have a close association with malnutrition and chronic inflammation, as well as with cognitive impairment. Impaired cognitive function may be manifested as low adherence to dialysis treatment, leading to malnutrition. Additionally, chronic pain and low quality of sleep lead to high rates of depressive symptoms in haemodialysis patients, while an untreated depression can cause sleep disturbances and increased mortality risk. Depression can also lead to sexual dysfunction and non-adherence, while unemployment can cause depressive disorders, due to patients' feelings of being a financial burden on their family. The present review provides a holistic approach to the factors affecting depression in haemodialysis, offering significant knowledge to renal professionals.

  12. A Holistic Approach to Interdisciplinary Innovation Supported by a Simple Tool

    DEFF Research Database (Denmark)

    Denise J. Stokholm, Marianne

    2008-01-01

    Innovation is recognised as a strategy to achieve competitive businesses and products. Managing innovation at all levels requires integration of knowledge and interdisciplinary cooperation. Different understandings and approaches to innovation between professions often result in communication...... problems. To overcome this barrier a common ground is needed. This paper describes a holistic approach to innovation and presents a simple tool for facilitating cooperation on a diversity of innovation matters. It describes the development and use of the tool and demonstrates its capacity to support...

  13. The Good Life: A Holistic Approach to the Health of the Population

    OpenAIRE

    Shahtahmasebi, Said

    2006-01-01

    The idea of a holistic approach towards public health planning presented itself through a food-related and trivial curiosity. It is, however, emphasized that food and nutrition are only one aspect of public health. The aim is to reintroduce a holistic approach to achieve sustainable public health with emphasis on the interpretation of the term “holistic”. Holistic decision making is not a new phenomenon and has historical basis. In line with shifts in social norms, decision making has evolved...

  14. A holistic approach to the treatment of irritable bowel syndrome ...

    African Journals Online (AJOL)

    Group 1 (n = 13) received IBS medication and holistic psychotherapy, Group 2 (n = 23) received IBS medication only, Group 3 (n = 13) received holistic psychotherapy only and Group 4 (n = 21) received no treatment until the study was completed. During the intervention phase the relevant participants received one-hour ...

  15. A Holistic Quality Evaluation, Selection and Improvement Approach driven by Multilevel Goals and Strategies

    Directory of Open Access Journals (Sweden)

    Belen Rivera

    2016-12-01

    Full Text Available Organizations should establish business goals and check for their achievement in a systematic and disciplined way. In order to know if a business goal is achieved, it should be necessary to consider information need goals that also can require satisfying measurement and evaluation goals at operational level. Furthermore, if measurement and evaluation goals are not aligned with top-level business goals such as tactical or strategic level goals, the organization could waste its effort and resources. Usually, the different goals established in an organization are operationalized through projects. For a given project, strategies should be used in order to help in the goal achievement. A strategy defines a set of activities and methods to be followed for a specific goal purpose. Ultimately, to engineering all these issues in a systematic way, organizations should adopt a holistic evaluation approach supported by a set of integrated strategies. By means of a systematic literature review as research method, we have observed that very few approaches support integrated strategies and multilevel goals. To bridge this gap, we have developed a holistic quality multilevel and multipurpose evaluation approach that ties together multilevel goals, projects and integrated strategies. As contributions, this paper discusses an enhanced conceptual base (specified by ontologies for linking business and information need goal concepts with project, strategy and nonfunctional requirements concepts. Then, it defines the step by step of our holistic quality evaluation approach, by listing the necessary activities to establish goals and projects at different organizational levels. Lastly, it specifies and illustrates evaluation scenarios for business/information need goal purposes such as understanding, improving, monitoring and controlling, comparing and selecting entities, which are supported by strategies and strategy patterns.

  16. Flow-based approach for holistic factory engineering and design

    OpenAIRE

    Constantinescu, C.; Westkämper, E.

    2010-01-01

    The engineering of future factories requires digital tools along life cycle phases from investment planning to ramp-up. Manufacturers need scientific-based integrated highly dynamic data management systems for the participative and integrated factory planning. The paper presents a new approach for the continuously integrated product design, factory and process planning, through a service-oriented architecture for the implementation of digital factory tools. A first prototype of the digital fa...

  17. Managing ambiguity in business. A holistic and innovative approach

    Directory of Open Access Journals (Sweden)

    Pop Oana

    2017-07-01

    Full Text Available This article will look at the hurdles of dealing with ambiguity and the wicked problems that organizations are struggling with, by providing key insights from a one year team coaching program that the author had the opportunity to deliver in a Romanian entrepreneurial organization. Based on the actual methods used and highlighting the findings and impact of the program, we will reflect on how ambiguity manifests in organizational settings and how wicked problems can be defined. The methods employed are within the range of complexity science and are holistic approaches to systemic interventions within organizations that combine soft systems methodology, paradoxical theory of change, complex responsive processes approach with important concepts from systems thinking such as archetypes, feedback loops and modeling. One of the key objectives of the article is to reunite different academic approaches and link them to a case study as a way of adding value to these approaches and to reiterate that research needs, to find its rightful place in the practitioners’ toolkit and have a more meaningful and direct impact on the real struggles that business is faced with. The author’s expertize in systemic interventions is based on extensive practitioner experience, having been trained and certified as a systemic coach and facilitator, and therefore draws upon the work of other skilled practitioners that support companies in finding successful ways to address complexity. Although the article can be easily put in the complexity science and systems thinking area of academic interest, the research questions and insights are intended to serve the learning and the evolution of organizations.

  18. Lotus birth, a holistic approach on physiological cord clamping.

    Science.gov (United States)

    Zinsser, Laura A

    2018-04-01

    The positive effects of delayed cord clamping (DCC) has been extensively researched. DCC means: waiting at least one minute after birth before clamping and cutting the cord or till the pulsation has stopped. With physiological clamping and cutting (PCC) the clamping and cutting can happen at the earliest after the pulsation has stopped. With a Lotus birth, no clamping and cutting of the cord is done. A woman called Clair Lotus Day imitated the holistic approach of PCC from an anthropoid ape in 1974. The chimpanzee did not separate the placenta from the newborn. The aim of this case report is to discuss and learn a different approach in the third stage of labour. Three cases of Lotus birth by human beings were observed. All three women gave birth in an out-of-hospital setting and had ambulant postnatal care. The placenta was washed, salted and herbs were put on 2-3h post partum. The placenta was wrapped in something that absorbs the moisture. The salting was repeated with a degreasing frequency depending on moistness of the placenta. On life day six all three Lotus babies experiences a natural separation of the cord. All three Lotus birth cases were unproblematic, no special incidence occurred. One should differentiate between early cord clamping (ECC), delayed cord clamping (DCC) and physiological cord clamping (PCC). Lotus birth might lead to an optimisation of the bonding and attachment. Research is needed in the areas of both PCC and Lotus birth. Copyright © 2017 Australian College of Midwives. Published by Elsevier Ltd. All rights reserved.

  19. A Holistic approach to assess older adults' wellness using e-health technologies.

    Science.gov (United States)

    Thompson, Hilaire J; Demiris, George; Rue, Tessa; Shatil, Evelyn; Wilamowska, Katarzyna; Zaslavsky, Oleg; Reeder, Blaine

    2011-12-01

    To date, methodologies are lacking that address a holistic assessment of wellness in older adults. Technology applications may provide a platform for such an assessment, but have not been validated. We set out to demonstrate whether e-health applications could support the assessment of older adults' wellness in community-dwelling older adults. Twenty-seven residents of independent retirement community were followed over 8 weeks. Subjects engaged in the use of diverse technologies to assess cognitive performance, physiological and functional variables, as well as psychometric components of wellness. Data were integrated from various e-health sources into one study database. Correlations were assessed between different parameters, and hierarchical cluster analysis was used to explore the validity of the wellness model. We found strong associations across multiple parameters of wellness within the conceptual model, including cognitive, functional, and physical. However, spirituality did not correlate with any other parameter studied in contrast to prior studies of older adults. Participants expressed overall positive attitudes toward the e-health tools and the holistic approach to the assessment of wellness, without expressing any privacy concerns. Parameters were highly correlated across multiple domains of wellness. Important clusters were noted to be formed across cognitive and physiological domains, giving further evidence of need for an integrated approach to the assessment of wellness. This finding warrants further replication in larger and more diverse samples of older adults to standardize and deploy these technologies across population groups.

  20. A holistic approach on the neurological benefits of music.

    Science.gov (United States)

    Jimenez-Dabdoub, Lily; Catterall, Jenn

    2015-09-01

    A holistic perspective on human beings allows health carers to achieve an understanding of all the physiological, psychological and social disturbances of the patient as a whole. Through this article we wish to focus on how music has holistic neurological benefits. Music-therapy interventions can be more accessible and even "self-managed" by the patient's relatives. They can reinforce social cohesion, family ties and patients' self-esteem and thus produce a better quality of life. Overall, it is important to consider the benefits that an evolutionary understanding of musical behaviour and a holistic clinical perspective of the role of music may bring for rehabilitation of a wide range of symptoms and conditions.

  1. Holistic Art Education: A Transformative Approach to Teaching Art

    Science.gov (United States)

    Campbell, Laurel H.

    2011-01-01

    Education in recent years has tended increasingly to narrow its focus, zeroing in on only those academic skills tested in high-stake assessments while ignoring many other aspects of children's development. Opposing this trend is an alternative movement, holistic education, which is concerned with cultivating and balancing all dimensions of the…

  2. An Open and Holistic Approach for Geo and Space Sciences

    Science.gov (United States)

    Ritschel, Bernd; Seelus, Christoph; Neher, Günther; Toshihiko, Iyemori; Yatagai, Akiyo; Koyama, Yukinobu; Murayama, Yasuhiro; King, Todd; Hughes, Steve; Fung, Shing; Galkin, Ivan; Hapgood, Mike; Belehaki, Anna

    2016-04-01

    Geo and space sciences thus far have been very successful, even often an open, cross-domain and holistic approach did not play an essential role. But this situation is changing rapidly. The research focus is shifting into more complex, non-linear and multi-domain specified phenomena, such as e.g. climate change or space environment. This kind of phenomena only can be understood step by step using the holistic idea. So, what is necessary for a successful cross-domain and holistic approach in geo and space sciences? Research and science in general become more and more dependent from a rich fundus of multi-domain data sources, related context information and the use of highly advanced technologies in data processing. Such buzzword phrases as Big Data and Deep Learning are reflecting this development. Big Data also addresses the real exponential growing of data and information produced by measurements or simulations. Deep Learning technology may help to detect new patterns and relationships in data describing high sophisticated natural phenomena. And further on, we should not forget science and humanities are only two sides of the same medal in the continuing human process of knowledge discovery. The concept of Open Data or in particular the open access to scientific data is addressing the free and open availability of -at least publicly founded and generated- data. The open availability of data covers the free use, reuse and redistribution of data which have been established with the formation of World Data Centers already more than 50 years ago. So, we should not forget, the foundation for open data is the responsibility of the individual scientist up until the big science institutions and organizations for a sustainable management of data. Other challenges are discovering and collecting the appropriate data, and preferably all of them or at least the majority of the right data. Therefore a network of individual or even better institutional catalog-based and at least

  3. Vision Restoration in Glaucoma by Activating Residual Vision with a Holistic, Clinical Approach: A Review.

    Science.gov (United States)

    Sabel, Bernhard A; Cárdenas-Morales, Lizbeth; Gao, Ying

    2018-01-01

    How to cite this article: Sabel BA, Cárdenas-Morales L, Gao Y. Vision Restoration in Glaucoma by activating Residual Vision with a Holistic, Clinical Approach: A Review. J Curr Glaucoma Pract 2018;12(1):1-9.

  4. The Good Life: A Holistic Approach to the Health of the Population

    Science.gov (United States)

    Shahtahmasebi, Said

    2006-01-01

    The idea of a holistic approach towards public health planning presented itself through a food-related and trivial curiosity. It is, however, emphasized that food and nutrition are only one aspect of public health. The aim is to reintroduce a holistic approach to achieve sustainable public health with emphasis on the interpretation of the term “holistic”. Holistic decision making is not a new phenomenon and has historical basis. In line with shifts in social norms, decision making has evolved. In particular, various complex models for public health have been proposed to respond to ever-increasing health issues. The advancement in mathematical sciences and technology has led to the quantification of health models. However, mathematical representations pose a major limitation on the holistic approach. Due to its evolutionary nature, human health is dynamically related to social, environmental, and other processes. With the current knowledge, it is difficult to quantify the evolution and feedback effects in holistic models. In this paper, the individual's and public's health is viewed as a dynamic process, but not independent of other dynamic processes (e.g., agriculture, economy, politics) that are all part of a much bigger process. Furthermore, it is argued that it is not merely sufficient to account for all known factors to be holistic. In this paper, the holistic conceptual model is illustrated, using public health as the central issue. The application of the conceptual model is also discussed using two practical examples. PMID:17370007

  5. The wholeness teaching in history lessons: A perspective essay from Gestalt approach to holistic approach

    OpenAIRE

    Ahmet Şimşek

    2008-01-01

    In these days, education researchs emphasise on learning. The importance of wholeness in learning is just realized. Because of this, the thesis that the way individuals sense the world is complete, is became more important. The studies which are emphasize on wholeness learning are Gestalt, contructivism and holistic thinking. In this study, it is claimed that teaching history will be more fruitfull by the wholeness learning approach. Because, by wholeness history teaching, it will be possible...

  6. The Sustainability Cone - A holistic framework to integrate sustainability thinking into manufacturing

    DEFF Research Database (Denmark)

    Rödger, Jan-Markus; Bey, Niki; Alting, Leo

    2016-01-01

    Integrating sustainability into manufacturing is a multifaceted endeavour. Global sustainability aspects and specific manufacturing success factors have to be combined with life cycle thinking in order to get the holistic view on manufacturing which is needed to make truly sustainability-oriented......Integrating sustainability into manufacturing is a multifaceted endeavour. Global sustainability aspects and specific manufacturing success factors have to be combined with life cycle thinking in order to get the holistic view on manufacturing which is needed to make truly sustainability...... - as the missing link which closes these gaps by providing necessary holistic and consistent overview while being aligned with established stage-gate project execution models, thus ensuring practical applicability as shown for a highly automated production cell. The paper shows how to apply life cycle target...

  7. Designing Pay-As-You-Throw schemes in municipal waste management services: A holistic approach

    International Nuclear Information System (INIS)

    Elia, Valerio; Gnoni, Maria Grazia; Tornese, Fabiana

    2015-01-01

    Highlights: • Pay-As-You-Throw (PAYT) schemes are becoming widespread in several countries. • Economic, organizational and technological issues have to be integrated in an efficient PAYT model design. • Efficiency refers to a PAYT system which support high citizen participation rates as well as economic sustainability. • Different steps and constraints have to be evaluated from collection services to type technologies. • An holistic approach is discussed to support PAYT systems diffusion. - Abstract: Pay-As-You-Throw (PAYT) strategies are becoming widely applied in solid waste management systems; the main purpose is to support a more sustainable – from economic, environmental and social points of view – management of waste flows. Adopting PAYT charging models increases the complexity level of the waste management service as new organizational issues have to be evaluated compared to flat charging models. In addition, innovative technological solutions could also be adopted to increase the overall efficiency of the service. Unit pricing, user identification and waste measurement represent the three most important processes to be defined in a PAYT system. The paper proposes a holistic framework to support an effective design and management process. The framework defines most critical processes and effective organizational and technological solutions for supporting waste managers as well as researchers

  8. Designing Pay-As-You-Throw schemes in municipal waste management services: A holistic approach

    Energy Technology Data Exchange (ETDEWEB)

    Elia, Valerio; Gnoni, Maria Grazia, E-mail: mariagrazia.gnoni@unisalento.it; Tornese, Fabiana

    2015-10-15

    Highlights: • Pay-As-You-Throw (PAYT) schemes are becoming widespread in several countries. • Economic, organizational and technological issues have to be integrated in an efficient PAYT model design. • Efficiency refers to a PAYT system which support high citizen participation rates as well as economic sustainability. • Different steps and constraints have to be evaluated from collection services to type technologies. • An holistic approach is discussed to support PAYT systems diffusion. - Abstract: Pay-As-You-Throw (PAYT) strategies are becoming widely applied in solid waste management systems; the main purpose is to support a more sustainable – from economic, environmental and social points of view – management of waste flows. Adopting PAYT charging models increases the complexity level of the waste management service as new organizational issues have to be evaluated compared to flat charging models. In addition, innovative technological solutions could also be adopted to increase the overall efficiency of the service. Unit pricing, user identification and waste measurement represent the three most important processes to be defined in a PAYT system. The paper proposes a holistic framework to support an effective design and management process. The framework defines most critical processes and effective organizational and technological solutions for supporting waste managers as well as researchers.

  9. Oral and General Health Promotion for Children: A Holistic Approach

    DEFF Research Database (Denmark)

    Cinar, Ayse Basak

    Inequalities in oral and general health have been rising globally; WHO calls for adoption of an integrated approach to their promotion as both share common risk factors. However, research about this issue among children is scarce. Based on the associations of such a research found in common for a...... to adopt healthy lifestyles, both in economically developing and developed countries. This book should be especially useful to researchers, professionals in dentistry and medicine, policy makers, and anyone else involved in provision of better health to community....... Turkish and Finnish children, this book underlies that oral health is turning out to be part of the global health culture, regardless of cultural differences and different oral health care systems. The book, further, by most recent literature, provides a review of 'Significance of Oral Health, Concept......Inequalities in oral and general health have been rising globally; WHO calls for adoption of an integrated approach to their promotion as both share common risk factors. However, research about this issue among children is scarce. Based on the associations of such a research found in common for all...

  10. [Recognizing prevention and treatment of burn sepsis with the concept of holistic integrative medicine].

    Science.gov (United States)

    Huan, J N

    2017-04-20

    Sepsis remains a major cause of death in severe burns. The effect of sepsis management is influenced by its complicated pathophysiologic changes. In order to improve the outcome of burn sepsis, the predisposing factor of sepsis after burn analyzed by advanced technology, the early prevention, antibiotics therapy, and combined treatment in severe burns with sepsis are discussed using the concept of holistic integrative medicine.

  11. Tunable Polarity Carbon Fibers, a Holistic Approach to Environmental Protection

    Directory of Open Access Journals (Sweden)

    M. Teresa García-Valverde

    2018-04-01

    Full Text Available The pollution of environmental resources is an issue of social concern worldwide. Chemistry is essential for the design of decontamination strategies and analytical approaches to detect and monitor the contamination. Sorptive materials are usually required in both approaches and green synthesis should be used to minimize their own environmental impact. Carbon fibers (CFs obtained by the pyrolysis of natural cellulose-rich materials fulfill these requirements. In this article, thirty CFs obtained under different conditions are chemically characterized and their sorption ability towards selected pollutants, covering a wide range of polarity, is evaluated. This study provides more profound knowledge related to the polarity of these materials, their interactions with chemical substances and allows the prediction of more appropriate materials (pyrolysis temperature and time in order to remove the given pollutant. Furthermore, the use of CFs as sorptive materials for the extraction of contaminants from water samples to assist with their instrumental detection is outlined. In this sense, the use of CFs and gas chromatography with mass spectrometric detection allows the detection of selected pollutants in the low ng/mL range. Thus, this article provides an integrated approach to the potential of CFs for environmental protection.

  12. Tunable Polarity Carbon Fibers, a Holistic Approach to Environmental Protection.

    Science.gov (United States)

    García-Valverde, M Teresa; Ledesma-Escobar, Carlos A; Lucena, Rafael; Cárdenas, Soledad

    2018-04-27

    The pollution of environmental resources is an issue of social concern worldwide. Chemistry is essential for the design of decontamination strategies and analytical approaches to detect and monitor the contamination. Sorptive materials are usually required in both approaches and green synthesis should be used to minimize their own environmental impact. Carbon fibers (CFs) obtained by the pyrolysis of natural cellulose-rich materials fulfill these requirements. In this article, thirty CFs obtained under different conditions are chemically characterized and their sorption ability towards selected pollutants, covering a wide range of polarity, is evaluated. This study provides more profound knowledge related to the polarity of these materials, their interactions with chemical substances and allows the prediction of more appropriate materials (pyrolysis temperature and time) in order to remove the given pollutant. Furthermore, the use of CFs as sorptive materials for the extraction of contaminants from water samples to assist with their instrumental detection is outlined. In this sense, the use of CFs and gas chromatography with mass spectrometric detection allows the detection of selected pollutants in the low ng/mL range. Thus, this article provides an integrated approach to the potential of CFs for environmental protection.

  13. An holistic approach to the problem of reactor ageing

    International Nuclear Information System (INIS)

    Phythian, W.; McElroy, R.; Druce, S.; Kovan, D.

    1992-01-01

    Understanding the process of ageing in reactors is essential to extending their lives beyond original design. To present a sound case -particularly regarding the level of embrittlement in reactor vessels due to radiation damage - an integrated approach using advanced assessment tools is needed. The techniques developed for the purpose involve, on the microscopic level, advanced neutron dosimetry and high resolution measurement techniques (eg advanced electron beam techniques and small angle neutron scattering) with which an analysis can be done of the radiation damage and the microstructural state of the steel test procedures (tensile, fracture toughness and Charpy impact) on standard and sub-sized specimens, the extent of radiation degradation can be characterised. finally, it is possible to predict how the degradation will evolve using physically-based models of embrittlement. (Author)

  14. Holistic integration of gaze cues in visual face and body perception: Evidence from the composite design.

    Science.gov (United States)

    Vrancken, Leia; Germeys, Filip; Verfaillie, Karl

    2017-01-01

    A considerable amount of research on identity recognition and emotion identification with the composite design points to the holistic processing of these aspects in faces and bodies. In this paradigm, the interference from a nonattended face half on the perception of the attended half is taken as evidence for holistic processing (i.e., a composite effect). Far less research, however, has been dedicated to the concept of gaze. Nonetheless, gaze perception is a substantial component of face and body perception, and holds critical information for everyday communicative interactions. Furthermore, the ability of human observers to detect direct versus averted eye gaze is effortless, perhaps similar to identity perception and emotion recognition. However, the hypothesis of holistic perception of eye gaze has never been tested directly. Research on gaze perception with the composite design could facilitate further systematic comparison with other aspects of face and body perception that have been investigated using the composite design (i.e., identity and emotion). In the present research, a composite design was administered to assess holistic processing of gaze cues in faces (Experiment 1) and bodies (Experiment 2). Results confirmed that eye and head orientation (Experiment 1A) and head and body orientation (Experiment 2A) are integrated in a holistic manner. However, the composite effect was not completely disrupted by inversion (Experiments 1B and 2B), a finding that will be discussed together with implications for future research.

  15. Developing a Holistic Approach for E-Learning Accessibility

    Directory of Open Access Journals (Sweden)

    Brian Kelly

    2004-10-01

    Full Text Available The importance of accessibility to digital resources is now widely acknowledged. The W3C WAI has played a significant role in promoting the importance of accessibility and developing a framework for accessible Web resources. The accessibility of e-learning provides additional challenges that may not be faced when providing access to other Web resources. The authors argue that there is a need for a more sophisticated model for addressing e-learning accessibility which takes into account the usability of e-learning, pedagogic issues and student learning styles in addition to technical and resource issues. The authors expand on these issues and propose a holistic model for the development of accessible e-learning resources.

  16. a Holistic Approach for Inspection of Civil Infrastructures Based on Computer Vision Techniques

    Science.gov (United States)

    Stentoumis, C.; Protopapadakis, E.; Doulamis, A.; Doulamis, N.

    2016-06-01

    In this work, it is examined the 2D recognition and 3D modelling of concrete tunnel cracks, through visual cues. At the time being, the structural integrity inspection of large-scale infrastructures is mainly performed through visual observations by human inspectors, who identify structural defects, rate them and, then, categorize their severity. The described approach targets at minimum human intervention, for autonomous inspection of civil infrastructures. The shortfalls of existing approaches in crack assessment are being addressed by proposing a novel detection scheme. Although efforts have been made in the field, synergies among proposed techniques are still missing. The holistic approach of this paper exploits the state of the art techniques of pattern recognition and stereo-matching, in order to build accurate 3D crack models. The innovation lies in the hybrid approach for the CNN detector initialization, and the use of the modified census transformation for stereo matching along with a binary fusion of two state-of-the-art optimization schemes. The described approach manages to deal with images of harsh radiometry, along with severe radiometric differences in the stereo pair. The effectiveness of this workflow is evaluated on a real dataset gathered in highway and railway tunnels. What is promising is that the computer vision workflow described in this work can be transferred, with adaptations of course, to other infrastructure such as pipelines, bridges and large industrial facilities that are in the need of continuous state assessment during their operational life cycle.

  17. A HOLISTIC APPROACH FOR INSPECTION OF CIVIL INFRASTRUCTURES BASED ON COMPUTER VISION TECHNIQUES

    Directory of Open Access Journals (Sweden)

    C. Stentoumis

    2016-06-01

    Full Text Available In this work, it is examined the 2D recognition and 3D modelling of concrete tunnel cracks, through visual cues. At the time being, the structural integrity inspection of large-scale infrastructures is mainly performed through visual observations by human inspectors, who identify structural defects, rate them and, then, categorize their severity. The described approach targets at minimum human intervention, for autonomous inspection of civil infrastructures. The shortfalls of existing approaches in crack assessment are being addressed by proposing a novel detection scheme. Although efforts have been made in the field, synergies among proposed techniques are still missing. The holistic approach of this paper exploits the state of the art techniques of pattern recognition and stereo-matching, in order to build accurate 3D crack models. The innovation lies in the hybrid approach for the CNN detector initialization, and the use of the modified census transformation for stereo matching along with a binary fusion of two state-of-the-art optimization schemes. The described approach manages to deal with images of harsh radiometry, along with severe radiometric differences in the stereo pair. The effectiveness of this workflow is evaluated on a real dataset gathered in highway and railway tunnels. What is promising is that the computer vision workflow described in this work can be transferred, with adaptations of course, to other infrastructure such as pipelines, bridges and large industrial facilities that are in the need of continuous state assessment during their operational life cycle.

  18. [Application of clinical nursing path integrated with holistic nursing in advanced schistosomiasis patients with ascites].

    Science.gov (United States)

    Mei-Zhi, Yuan; Jing-Ru, Sun; Tao, Chen; Xiao-Yu, Zhang; Liang-Cai, He; Jia-Song, Wang

    2016-05-12

    To evaluate the effect of the clinical nursing path integrated with the holistic nursing on advanced schistosomiasis patients with ascites. A total of 226 advanced schistosomiasis patients with ascites were randomly divided into a control group and an experimental group (113 cases each group). The subjects in the experimental group were nursed by the clinical nursing path integrated with the holistic nursing, while those in the control group were nursed only by the holistic nursing. Then the clinical relevant indexes of the two groups were observed, and the quality of life of the patients before and after hospital discharge was assessed. The improvement rate, satisfaction degree, and awareness rate of health knowledge of the patients in the experiment group were 93.8%, 100% and 97.4%, respectively, which were significantly higher than those of the control group (all P holistic nursing can effectively improve the improvement rate and decrease the mortality of the advanced schistosomiasis patients with ascites; meanwhile, it can shorten the hospitalization time and save the hospitalization cost. Therefore, this nursing model is suitable for popularization and application in the treatment and nursing work of the advanced schistosomiasis assistance.

  19. A holistic approach to the management of Erb's palsy

    Science.gov (United States)

    Srilakshmi, Dasari; Chaganti, Sreelakshmi

    2013-01-01

    A 4.5-month-old female baby, presenting with complete paralysis of right upper limb with typical waiter's tip deformity, diagnosed as Erb's palsy was brought to Sri Ganapati Sachchidananda Hospital. Patient was treated with an integrated approach of physiotherapy and Ayurvedic treatment with an intention of aiding faster recovery of the patient to lead a near normal life. As per Ayurvedic classics, this condition can be correlated to Ekangavata (Vata effecting any one part of the body), which is Apatarpana in nature (diseases with deprived growth of body tissue). Hence, the choice of treatment is Santarpana Chikitsa (nourishing treatment). Santarpana Bahyopakramas (nourishing external treatment modalities) such as Ashwagandhabalalakshadi Taila (Ayurvedic medicated oil) Abhyanga (oleation therapy) and Shastikashali Anna Lepa (application of processed rice paste) were administered along with electrical stimulation (physiotherapy modality), both galvanic and faradic current in three sessions. Appreciable results were observed in the form of reduction of disparity in length and mid-arm circumference of right upper limb compared to unaffected left upper limb and the muscle power too improved from zero to four, facilitating patient to near normal movement. PMID:24459391

  20. [Occlusion: current situation and prospect in view of holistic integrative medicine].

    Science.gov (United States)

    Wang, M Q; Liu, X D

    2017-08-09

    The rise of holistic integrative medicine (HIM) is an inevitable consequence of modern medical development which emphasizes the change from specialization to integration of the most advanced medical knowledge. It does not mean a simple collection of the medical theories, but means the digestion of those theories for the clinical practical application. Because occlusal therapy is characterized as not only a high level of individualization, but also a relation to many stomatology and other disciplines, such as plastic surgery, orthopedics, neurosciences and psychology. It needs the HIM to guide the clinical practice. With undertaking occlusal therapy, to avoid the limitation due to the excessive specialized disciplines, and to provide effective treatment plans for abnormal occlusion induced diseases, it is necessary to develop the discipline of the holistic integrative stomatology.

  1. Naturopathic physicians: holistic primary care and integrative medicine specialists.

    Science.gov (United States)

    Litchy, Andrew P

    2011-12-01

    The use of Complimentary and Alternative Medicine (CAM) is increasing in the United States; there is a need for physician level practitioners who possess extensive training in both CAM and conventional medicine. Naturopathic physicians possess training that allows integration of modern scientific knowledge and the age-old wisdom of natural healing techniques. Naturopathic philosophy provides a framework to implement CAM in concert with conventional therapies. The naturopathic physician's expertise in both conventional medicine and CAM allows a practice style that provides excellent care through employing conventional and CAM modalities while utilizing modern research and evidence-based medicine.

  2. Identifying Key Performance Indicators for Holistic Hospital Management with a Modified DEMATEL Approach.

    Science.gov (United States)

    Si, Sheng-Li; You, Xiao-Yue; Liu, Hu-Chen; Huang, Jia

    2017-08-19

    Performance analysis is an important way for hospitals to achieve higher efficiency and effectiveness in providing services to their customers. The performance of the healthcare system can be measured by many indicators, but it is difficult to improve them simultaneously due to the limited resources. A feasible way is to identify the central and influential indicators to improve healthcare performance in a stepwise manner. In this paper, we propose a hybrid multiple criteria decision making (MCDM) approach to identify key performance indicators (KPIs) for holistic hospital management. First, through integrating evidential reasoning approach and interval 2-tuple linguistic variables, various assessments of performance indicators provided by healthcare experts are modeled. Then, the decision making trial and evaluation laboratory (DEMATEL) technique is adopted to build an interactive network and visualize the causal relationships between the performance indicators. Finally, an empirical case study is provided to demonstrate the proposed approach for improving the efficiency of healthcare management. The results show that "accidents/adverse events", "nosocomial infection", ''incidents/errors", "number of operations/procedures" are significant influential indicators. Also, the indicators of "length of stay", "bed occupancy" and "financial measures" play important roles in performance evaluation of the healthcare organization. The proposed decision making approach could be considered as a reference for healthcare administrators to enhance the performance of their healthcare institutions.

  3. [New theory of holistic integrative physiology and medicine. I: New insight of mechanism of control and regulation of breathing].

    Science.gov (United States)

    Sun, Xing-guo

    2015-07-01

    The modern systemic physiology, based on limit-understand functional classification, has significant limitation and one-sidedness. Human being is organic; we should approach the mechanism of control and regulation of breathing integrating all the systems. We use new theory of holistic integrative physiology and medicine to explain the mechanism of control and regulation of breathing. Except the mean level information, the up-down "W" waveform information of arterial blood gas (ABG) is core signal to control and regulate breathing. In order to do so, we must integrate all systems together. New theory will help to explain some unanswered questions in physiology and medicine, for example: fetal does not breathing; how first breath generate; how respiratory rhythm and frequency generate, etc. Breathing is the sign of life. Mechanism of control and regulation of breathing has to integrate respiration, circulation, nerves, metabolism, exercise, sleep and digestion, absorption and elimination and etc altogether.

  4. [Establishment of diagnosis and treatment patterns of holistic integrated medicine for neuro-ophthalmology].

    Science.gov (United States)

    Wang, Yanling

    2014-12-01

    Neuro-ophthalmology, as an interdisciplinary, covers at least three disciplines- ophthalmology, neurology and neurosurgery. With limited knowledge in each discipline, doctors often make misdiagnoses for neuro-ophthalmology diseases. Therefore, it is imperative to abandon the distinction between disciplines and combine all the knowledge to diagnose and treat patients in patterns of holistic integrated medicine in order to effectively improve the diagnosis and treatment of neuro-ophthalmology.

  5. From a holistic approach of public policy to co-governance

    Directory of Open Access Journals (Sweden)

    Luminiţa-Gabriela POPESCU

    2013-07-01

    Full Text Available In the context of the current paper, the holistic approach means the extrapolation of the concept of citizen towards the level of co-participant in public policy process.The paper is focused on the transformation of public policies in the holistic perspective, as well as on the creation of conditions favourable to such approach.It means to emphasise issues linked, on the one hand, to how prepared the political representatives and public authorities are to accept both the direct involvement of citizens in decision-making and sharing of accountability in public policy process, and, on the other hand, the direct citizens’ involvement. In other words, the paper attempts to identify possible responses to key matters for the holistic approach: On the one hand, are the members of community aware of the importance of commitment? Are they truly motivated to take part in such a structure? On the other hand, how are prepared the political representatives and public authorities to accept co-operation with different categories of stakeholders?The researches in Romania reveal that unfortunately the actual context is not favourable to the holistic approach. The current conditions are just at minimal level, the policies will be further made behind closed doors and the citizens’ consultation will be mainly formal.

  6. Primary School Teachers' Views on a Holistic Approach to Facilitating the Acquisition of Musical Cultural Values

    Science.gov (United States)

    Badjanova, Jelena

    2013-01-01

    Recent tendencies in education highlight the need to align the system of general education in Latvia with the tenets of sustainability. In keeping with this broad target orientation, this paper re-examines international and Latvian experiences and perspectives on the application of a holistic approach to the content of primary education. This…

  7. Improving "At-Action" Decision-Making in Team Sports through a Holistic Coaching Approach

    Science.gov (United States)

    Light, Richard L.; Harvey, Stephen; Mouchet, Alain

    2014-01-01

    This article draws on Game Sense pedagogy and complex learning theory (CLT) to make suggestions for improving decision-making ability in team sports by adopting a holistic approach to coaching with a focus on decision-making "at-action". It emphasizes the complexity of decision-making and the need to focus on the game as a whole entity,…

  8. Healing the Physical/Spiritual Divide through a Holistic and Hermeneutic Approach to Education

    Science.gov (United States)

    Webster, R. Scott

    2013-01-01

    In this special edition of the journal, attention is being given to the two dimensions of spirituality and physicality. In this particular paper I argue that there is an unhelpful divide that is often assumed to exist between these two dimensions and that this divide can be transcended or "healed" through a holistic and hermeneutic approach to…

  9. A Holistic Approach to Promoting Physical Activity among School-Age Children

    Science.gov (United States)

    Subramaniam, Prithwi Raj

    2011-01-01

    A holistic approach to promote physical activity should become a high priority if society is to overcome the dramatic increase in physical inactivity and kypokinetic diseases associated with it. In order to achieve this goal, a collective effort is urgently needed if everyone is serious in combating this unhealthy and dangerous trend. Schools as a…

  10. Holistic Treatment Approaches to ADHD: Nutrition, Sleep,and Exercise, Part 7

    Science.gov (United States)

    Lavoie, Theresa

    2009-01-01

    This article is part of a series exploring Attention Deficit Hyperactivity Disorder (ADHD). In this seventh installment, the author discusses three holistic treatments for children and adults with ADHD: diet and nutrition, sleep, and exercise. These approaches focus and improve the overall health of ADHD patients. (For Part 6 of this series, see…

  11. Holistic Approach to Learning and Teaching Introductory Object-Oriented Programming

    Science.gov (United States)

    Thota, Neena; Whitfield, Richard

    2010-01-01

    This article describes a holistic approach to designing an introductory, object-oriented programming course. The design is grounded in constructivism and pedagogy of phenomenography. We use constructive alignment as the framework to align assessments, learning, and teaching with planned learning outcomes. We plan learning and teaching activities,…

  12. A holistic approach to determine tree structural complexity based on laser scanning data and fractal analysis.

    Science.gov (United States)

    Seidel, Dominik

    2018-01-01

    The three-dimensional forest structure affects many ecosystem functions and services provided by forests. As forests are made of trees it seems reasonable to approach their structure by investigating individual tree structure. Based on three-dimensional point clouds from laser scanning, a newly developed holistic approach is presented that enables to calculate the box dimension as a measure of structural complexity of individual trees using fractal analysis. It was found that the box dimension of trees was significantly different among the tested species, among trees belonging to the same species but exposed to different growing conditions (at gap vs. forest interior) or to different kinds of competition (intraspecific vs. interspecific). Furthermore, it was shown that the box dimension is positively related to the trees' growth rate. The box dimension was identified as an easy to calculate measure that integrates the effect of several external drivers of tree structure, such as competition strength and type, while simultaneously providing information on structure-related properties, like tree growth.

  13. A self-efficacy approach to holistic student development | Wood ...

    African Journals Online (AJOL)

    South African Journal of Education ... It is argued that student acquisition of the necessary social and academic skills will be more successful if ... can approach their tasks with confidence, a positive attitude, and the belief that they can succeed.

  14. A Holistic Treatment Approach to Male Erectile Disorder.

    Science.gov (United States)

    Millner, Vaughn S.; Ullery, Elizabeth K.

    2002-01-01

    This article offers information about erectile functioning, provides a DSM-IV-TR interpretation of erectile dysfunction, and discusses a biophysical approach to erectile dysfunction treatment. (Contains 36 references.) (GCP)

  15. Managing pressures ulcers in a resource constrained situation: A holistic approach

    Directory of Open Access Journals (Sweden)

    Abhijit Dam

    2011-01-01

    Full Text Available Managing pressure ulcers remain a challenge and call for a multidisciplinary team approach to care. Even more daunting is the management of such patients in remote locations and in resource constrained situations. The management of pressure sores in a patient with progressive muscular atrophy has been discussed using resources that were locally available, accessible, and affordable. Community participation was encouraged. A holistic approach to care was adopted.

  16. Solar Plus: A Holistic Approach to Distributed Solar PV

    Energy Technology Data Exchange (ETDEWEB)

    O' Shaughnessy, Eric [National Renewable Energy Lab. (NREL), Golden, CO (United States); Ardani, Kristen [National Renewable Energy Lab. (NREL), Golden, CO (United States); Cutler, Dylan [National Renewable Energy Lab. (NREL), Golden, CO (United States); Margolis, Robert [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2017-05-25

    Solar 'plus' refers to an emerging approach to distributed solar photovoltaic (PV) deployment that uses energy storage and controllable devices to optimize customer economics. The solar plus approach increases customer system value through technologies such as electric batteries, smart domestic water heaters, smart air-conditioner (AC) units, and electric vehicles We use an NREL optimization model to explore the customer-side economics of solar plus under various utility rate structures and net metering rates. We explore optimal solar plus applications in five case studies with different net metering rates and rate structures. The model deploys different configurations of PV, batteries, smart domestic water heaters, and smart AC units in response to different rate structures and customer load profiles. The results indicate that solar plus improves the customer economics of PV and may mitigate some of the negative impacts of evolving rate structures on PV economics. Solar plus may become an increasingly viable model for optimizing PV customer economics in an evolving rate environment.

  17. A Holistic Approach for Risk Management During Design

    Science.gov (United States)

    Meshkat, Leila

    2006-01-01

    In this paper, an approach for the identification, assessment, mitigation and continuous management of risks during the process of designing a space mission is presented. This approach has been developed by observing the risk patterns that occur at the Project Design Center of the Jet Propulsion Laboratory (TeamX) which develops conceptual, concurrent design of Space Missions. TeamX develops an end-to-end conceptual design of a Space Mission in a matter of one or two weeks. As the risk chair in TeamX, the author has had the opportunity to observe the risk patterns that occur during design over the course of many design sessions. This paper introduces an abstraction and generalization of those patterns. Risk is defined as anything that can go wrong, along with its approximate likelihood and consequence. The indicators, and causes, and effects of these risks are cross cutting across the multiple levels of people and processes involved in the design, and the actual design product itself.

  18. A holistic approach to managing a patient with heart failure.

    Science.gov (United States)

    Duncan, Alison; Cunnington, Colin

    2013-03-01

    Despite varied and complex therapeutic strategies for managing patients with heart failure, the prognosis may remain poor in certain groups. Recognition that patients with heart failure frequently require input from many care groups formed the basis of The British Society of Heart Failure Annual Autumn Meeting in London (UK), in November 2012, entitled: 'Heart failure: a multidisciplinary approach'. Experts in cardiology, cardiac surgery, general practice, care of the elderly, palliative care and cardiac imaging shared their knowledge and expertise. The 2-day symposium was attended by over 500 participants from the UK, Europe and North America, and hosted physicians, nurses, scientists, trainees and representatives from the industry, as well as patient and community groups. The symposium, accredited by the Royal College of Physicians and the Royal College of Nursing, focused on the multidisciplinary approach to heart failure, in particular, current therapeutic advances, cardiac remodeling, palliative care, atrial fibrillation, heart rate-lowering therapies, management of acute heart failure and the management of patients with mitral regurgitation and heart failure.

  19. Solar Plus: A Holistic Approach to Distributed Solar PV

    Energy Technology Data Exchange (ETDEWEB)

    OShaughnessy, Eric J. [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Ardani, Kristen B. [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Cutler, Dylan S. [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Margolis, Robert M. [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2017-06-08

    Solar 'plus' refers to an emerging approach to distributed solar photovoltaic (PV) deployment that uses energy storage and controllable devices to optimize customer economics. The solar plus approach increases customer system value through technologies such as electric batteries, smart domestic water heaters, smart air-conditioner (AC) units, and electric vehicles We use an NREL optimization model to explore the customer-side economics of solar plus under various utility rate structures and net metering rates. We explore optimal solar plus applications in five case studies with different net metering rates and rate structures. The model deploys different configurations of PV, batteries, smart domestic water heaters, and smart AC units in response to different rate structures and customer load profiles. The results indicate that solar plus improves the customer economics of PV and may mitigate some of the negative impacts of evolving rate structures on PV economics. Solar plus may become an increasingly viable model for optimizing PV customer economics in an evolving rate environment.

  20. A HOLISTIC APPROACH FOR DISPOSITION OF LONG-LIVED RADIOACTIVE MATERIALS

    Energy Technology Data Exchange (ETDEWEB)

    Eriksson, Leif G.; Dials, George E.; Parker, Frank L.

    2003-02-27

    -disposition components considered either ''proven'' or ''promising'' by the authors. The fundamental principles of the holistic approach are: (1) Risk minimization; (2) Minimization of the LLRM volume requiring deep geological disposal; and (3) LLRM-disposition flexibility. An integral element of these principles is to allow time for LLRM-disposition solutions to evolve/mature technically, financially, and politically. Furthermore, contingent upon the desired outcome(s), available financial, scientific, and technical resources, and political will, these components may be implemented separately or in combinations by one or a group of nations.

  1. A HOLISTIC APPROACH FOR DISPOSITION OF LONG-LIVED RADIOACTIVE MATERIALS

    International Nuclear Information System (INIS)

    Eriksson, Leif G.; Dials, George E.; Parker, Frank L.

    2003-01-01

    fundamental principles of the holistic approach are: (1) Risk minimization; (2) Minimization of the LLRM volume requiring deep geological disposal; and (3) LLRM-disposition flexibility. An integral element of these principles is to allow time for LLRM-disposition solutions to evolve/mature technically, financially, and politically. Furthermore, contingent upon the desired outcome(s), available financial, scientific, and technical resources, and political will, these components may be implemented separately or in combinations by one or a group of nations

  2. The study of the landscape: from a holistic approach to a social concept of knowledges

    Directory of Open Access Journals (Sweden)

    Federica Badiali

    2012-07-01

    Full Text Available Three examples of the study and enhancement of the landscape in Italy are presented. The interdisciplinary approach to this topic is carried out not simply by juxtaposing disciplines, but by the integration of different ambits. In this way, disjunctive thought is substituted by a holistic approach that produces communication more appropriate to research. This offers the scientists a tool that is of paramount importance for their studies, and for ordinary citizens, a new way of considering the landscape. Example 1: Sustainable tourism and man–landscape relationships: Ecomuseum, Castello di Serravalle (Bologna. By studying the landscape of a hilly wine-producing area, it has been possible to observe the signs of reciprocal man–environment interactions that have characterized the area for over two millennia. For this reason, an Ecomuseum was founded, to provide an efficient tool for the enhancement of sustainable tourism, and also to popularize knowledge of local cultural heritage among the citizens. Example 2: Lago Bracciano near Montese (Modena: re-assessment of an Apennine area combining archeology, landscape and history. The landscape of areas containing historical settlements of local populations was reconstructed. This started with archeological and documentary data that had not yet been correlated, which was integrated with geological and geochemical data. In this way, a marginal tourism area has been improved by appraisal of its intrinsic cultural and historical values. Example 3: Geological elements and poetic trails in Frignano Park. This geological–literary itinerary starts from the assumption that there is a specific poetic and cultural value to the Modena Apennines that is linked to the morphological and geological features of this territory. Geology and literature become an accompaniment to a new pilgrimage of knowledge.

  3. A Holistic Approach to Managing Microalgae for Biofuel Applications

    Directory of Open Access Journals (Sweden)

    Pau Loke Show

    2017-01-01

    Full Text Available Microalgae contribute up to 60% of the oxygen content in the Earth’s atmosphere by absorbing carbon dioxide and releasing oxygen during photosynthesis. Microalgae are abundantly available in the natural environment, thanks to their ability to survive and grow rapidly under harsh and inhospitable conditions. Microalgal cultivation is environmentally friendly because the microalgal biomass can be utilized for the productions of biofuels, food and feed supplements, pharmaceuticals, nutraceuticals, and cosmetics. The cultivation of microalgal also can complement approaches like carbon dioxide sequestration and bioremediation of wastewaters, thereby addressing the serious environmental concerns. This review focuses on the factors affecting microalgal cultures, techniques adapted to obtain high-density microalgal cultures in photobioreactors, and the conversion of microalgal biomass into biofuels. The applications of microalgae in carbon dioxide sequestration and phycoremediation of wastewater are also discussed.

  4. Research Quality Plus (RQ+) A Holistic Approach to Evaluating Research

    Energy Technology Data Exchange (ETDEWEB)

    McLean, R.K.D.; Feinstein, O.N.

    2016-07-01

    The International Development Research Centre (IDRC) strives to fund excellence in research - defining excellence as, {sup m}ethodologically sound, evidence-based, and scientifically robust{sup .} But how is the concept of excellence identified and evaluated across the diverse range of research the IDRC supports? The Research Quality Plus (RQ+) Assessment Framework was developed in order to address these complex issues. It provides a systems-informed approach to defining and evaluating the quality of research, and its positioning for use and impact. It allows tailoring to context, values, mandate and purpose, and can support planning, management and learning processes at any stage in the lifetime of a research project, program or grants portfolio. This paper presents: 1) the rationale for RQ+ creation, 2) the RQ+ Assessment Framework, and how it can be adapted and used, 3) our early experiences applying it in a series of extenal evaluations of research quality. The paper is presented by an RQ+ designer and an external user. (Author)

  5. [To see the future development of burn medicine from the view of holistic integrative medicine].

    Science.gov (United States)

    Hu, D H; Tao, K

    2017-04-20

    The therapeutic methods and effects have been improved greatly in the past few decades for burn care and management with several important advancements which have resulted in more effective patient stabilization and significantly decreased mortality in China. However, the challenges still exist, such as how to further improve the recovery of the patients' appearance and function, and how to advance the treatment of severe deep extensive burn injury, etc. The theory of holistic integrative medicine (HIM) provides a new opportunity for the development of clinical medicine. This article emphasizes the important roles of HIM in exploration of burn medicine, considering the advanced development of modern life sciences and relevant techniques.

  6. A holistic approach to corporate social responsibility as a prerequisite for sustainable development: Empirical evidence

    Directory of Open Access Journals (Sweden)

    Zlatanović Dejana

    2015-01-01

    Full Text Available The growing importance of sustainable development and corporate social responsibility (CSR for contemporary organizations demands appropriate holistic tools. The paper highlights how Soft Systems Methodology (SSM, a relevant holistic, i.e., soft systems approach, supports the conceptualization and management of the complex issues of CSR and sustainable development. The SSM’s key methodological tools are used: rich picture, root definitions, and conceptual models. Empirical research compares a selected sample of enterprises in the automotive industry in the Republic of Serbia, to identify possible systemically desirable and culturally feasible changes to improve their CSR behaviour through promoting their sustainable development. Some limitations of this research and of SSM application are discussed. Combining SSM with some other systems approaches, such as System Dynamics or Critical Systems Heuristics, is recommended for future research.

  7. Organizational Wellness Program Implementation and Evaluation: A Holistic Approach to Improve the Wellbeing of Middle Managers.

    Science.gov (United States)

    Medina, Maria Del Consuelo; Calderon, Angelica; Blunk, Dan I; Mills, Brandy W; Leiner, Marie

    2018-06-01

    : Employee wellness programs can provide benefits to institutions as well as employees and their families. Despite the attempts of some organizations to implement programs that take a holistic approach to improve physical, mental, and social wellness, the most common programs are exclusively comprised of physical and nutritional components. In this study, we implemented a wellness program intervention, including training using a holistic approach to improve the wellbeing of middle managers in several multinational organizations. We included control and experimental groups to measure wellness and teamwork with two repeated measures. Our results indicated that employees receiving the intervention had improved measures of wellness and teamwork. A positive relationship was found between wellness and teamwork in the experimental group when compared with the control group. Taken together, the data suggest that implementation of these programs would provide valuable outcomes for both employees and organizations.

  8. Toward a Holistic Approach to Spiritual Health Care for People With Schizophrenia.

    Science.gov (United States)

    Ho, Rainbow T H; Wan, Adrian H Y; Chan, Caitlin K P

    2016-01-01

    Medical and behavioral treatments are the predominant types of rehabilitation services for people with schizophrenia. Spirituality in people with schizophrenia remains poorly conceptualized, thereby limiting knowledge advancement in the area of spiritual health care services. To provide a framework for better clinical and research practices, we advocate a holistic approach to investigating spirituality and its application in spiritual health care services of people with schizophrenia.

  9. Holistic Approach for Human Resource Management in Industry 4.0

    OpenAIRE

    Hecklau, Fabian; Galeitzke, Mila; Flachs, Sebastian; Kohl, Holger

    2016-01-01

    To cope with knowledge and competence challenges related to new technologies and processes of Industry 4.0 new strategic approaches for holistic human resource management are needed in manufacturing companies. Due to the continuous automation of simple manufacturing processes, the number of workspaces with a high level of complexity will increase, which results in the need of high level of education of the staff. The challenge is to qualify employees to shift their capacities to workspaces wi...

  10. Integrated Assessment of Left Ventricular Electrical Activation and Myocardial Strain Mapping in Heart Failure Patients: A Holistic Diagnostic Approach for Endocardial Cardiac Resynchronization Therapy, Ablation of Ventricular Tachycardia, and Biological Therapy.

    Science.gov (United States)

    Maffessanti, Francesco; Prinzen, Frits W; Conte, Giulio; Regoli, François; Caputo, Maria Luce; Suerder, Daniel; Moccetti, Tiziano; Faletra, Francesco; Krause, Rolf; Auricchio, Angelo

    2018-01-01

    This study sought to test the accuracy of strain measurements based on anatomo-electromechanical mapping (AEMM) measurements compared with magnetic resonance imaging (MRI) tagging, to evaluate the diagnostic value of AEMM-based strain measurements in the assessment of myocardial viability, and the additional value of AEMM over peak-to-peak local voltages. The in vivo identification of viable tissue, evaluation of mechanical contraction, and simultaneous left ventricular activation is currently achieved using multiple complementary techniques. In 33 patients, AEMM maps (NOGA XP, Biologic Delivery Systems, Division of Biosense Webster, a Johnson & Johnson Company, Irwindale, California) and MRI images (Siemens 3T, Siemens Healthcare, Erlangen, Germany) were obtained within 1 month. MRI tagging was used to determine circumferential strain (E cc ) and delayed enhancement to obtain local scar extent (%). Custom software was used to measure E cc and local area strain (LAS) from the motion field of the AEMM catheter tip. Intertechnique agreement for E cc was good (R 2  = 0.80), with nonsignificant bias (0.01 strain units) and narrow limits of agreement (-0.03 to 0.06). Scar segments showed lower absolute strain amplitudes compared with nonscar segments: E cc (median [first to third quartile]: nonscar -0.10 [-0.15 to -0.06] vs. scar -0.04 [-0.06 to -0.02]) and LAS (-0.20 [-0.27 to -0.14] vs. -0.09 [-0.14 to -0.06]). AEMM strains accurately discriminated between scar and nonscar segments, in particular LAS (area under the curve: 0.84, accuracy = 0.76), which was superior to peak-to-peak voltages (nonscar 9.5 [6.5 to 13.3] mV vs. scar 5.6 [3.4 to 8.3] mV; area under the curve: 0.75). Combination of LAS and peak-to-peak voltages resulted in 86% accuracy. An integrated AEMM approach can accurately determine local deformation and correlates with the scar extent. This approach has potential immediate application in the diagnosis, delivery of intracardiac therapies, and their

  11. [New theory of holistic integrative physiology and medicine. III: New insight of neurohumoral mechanism and pattern of control and regulation for core axe of respiration, circulation and metabolism].

    Science.gov (United States)

    Sun, Xing-guo

    2015-07-01

    Systemic mechanism of neurohumoral control and regulation for human is limited. We used the new theory of holistic integrative physiology and medicine to approach the mechanism and pattern of neurohumoral control and regulation for life. As the core of human life, there are two core axes of functions. The first one is the common goal of respiration and circulation to transport oxygen and carbon dioxide for cells, and the second one is the goal of gastrointestinal tract and circulation to transport energy material and metabolic product for cells. These two core axes maintain the metabolism. The neurohumoral regulation is holistically integrated and unified for all functions in human body. We simplified explain the mechanism of neurohumoral control and regulation life (respiration and circulation) as the example pattern of sound system. Based upon integrated regulation of life, we described the neurohumoral pattern to control respiration and circulation.

  12. [Holistic integrative medicine: application in prevention and treatment of oral mucosal diseases].

    Science.gov (United States)

    Jin, X; Xie, L; Zhao, X; Li, J; Zeng, X; Chen, Q M

    2017-08-09

    Holistic integrative medicine (HIM), as one of the important ideas in the field of medicine, arouses great concern recently. HIM regards the human body as a whole, turns data and evidence in medical research back to facts, integrates technologies and experience developed in clinical research into medical skills. The repeated practices at the levels of fact, experience, and medical skills will generate true knowledge to solve the wide spread problems brought by linearized thinking and fragmented knowledge. With the development of highly divided medical disciplines, how to utilize and practice HIM has become a common concern of the medical community. Specialization of stomatology, which is a first level discipline like medicine, has also become a trend for years. However, holistic concept cannot be overlooked, especially in the development of oral medicine. This article aims at the communication and exchange of knowledge about HIM among dental professionals. In order to serve the patients better, the authors look forward to practicing the HIM concept in the field of oral medicine through the efforts of us all.

  13. Holistic approach to education and upbringing: Contradictory to the general assumption of life

    Directory of Open Access Journals (Sweden)

    Mihajlović Ljubiša M.

    2014-01-01

    Full Text Available Holistic education is a compprehensive view of education based on the assumption that each individual finds his own identity, meaning and objective in life through the connection with the community, nature and human values such as compassion and peace. Within holistic education the teacher is viewed not as an authority figure who guides and controls, but rather as a 'friend', a facilitator of learning: a guide and a companion in gaining experience. The norm is cooperation rather than competition. However, is this possible in real life? The answer is simple - it is not. Why? The reason why lies in the foundation of life itself: a molecule built in such a way that it does not permit such an idealistic approach to life, and therefore, to education. It is a DNK molecule: the molecule of life exhibiting, among other, the following characteristics: it seeks procreation, and exhibits the tendency of eternal struggle, competition. This is in stark opposition to holistic approach to education which does not recognize competition, struggle, gradation and rivalry. The development of an advanced and socially responsible society demands partial, measured application of holism. This needs to be reflected in education as well: approved competition, clear and fair gradation, the best in certain areas become the elite, with the rest following or to be found solutions in accordance with their abilities.

  14. A qualitative study of medical educators' perspectives on remediation: Adopting a holistic approach to struggling residents.

    Science.gov (United States)

    Krzyzaniak, Sara M; Wolf, Stephen J; Byyny, Richard; Barker, Lisa; Kaplan, Bonnie; Wall, Stephen; Guerrasio, Jeannette

    2017-09-01

    During residency, some trainees require the identification and remediation of deficiencies to achieve the knowledge, skills and attitudes necessary for independent practice. Given the limited published frameworks for remediation, we characterize remediation from the perspective of educators and propose a holistic framework to guide the approach to remediation. We conducted semistructured focus groups to: explore methods for identifying struggling residents; categorize common domains of struggle; describe personal factors that contribute to difficulties; define remediation interventions and understand what constitutes successful completion. Data were analyzed through conventional content analysis. Nineteen physicians across multiple specialties and institutions participated in seven focus groups. Thirteen categories emerged around remediation. Some themes addressed practical components of remediation, while others reflected barriers to the process and the impact of remediation on the resident and program. The themes were used to inform development of a novel holistic framework for remediation. The approach to remediation requires comprehensive identification of individual factors impacting performance. The intervention should not only include a tailored learning plan but also address confounders that impact likelihood of remediation success. Our holistic framework intends to guide educators creating remediation plans to ensure all domains are addressed.

  15. Forensic nursing interventions with patients with personality disorder: a holistic approach.

    Science.gov (United States)

    Byrt, Richard

    2013-01-01

    Research findings suggest that nursing assessment and care and psychotherapy of forensic patients with personality disorder should be based on a holistic approach that addresses a wide range of their needs. Such an approach should be in collaboration with patients, informal carers, and other professionals and informed by appropriate education, training, clinical supervision, and support. Holistic care includes areas (such as physical health, cultural, spiritual, and psychosexual needs) that are addressed to a limited extent in the literature on patients with personality disorder. Despite limitations in research evidence, findings suggest that some patients with personality disorder benefit from psychotherapies, sometimes facilitated by nurse-therapists, and therapeutic community principles. These interventions should take account of patients' cultural and spiritual needs and perspectives. Helping patients to manage anger has potentially positive consequences for their physical health, personal and work relationships, and other areas. Research is needed to consider how to deliver holistic care with limited resources and in organizations, such as prisons, with conflicting goals.

  16. Contractual framework of private-public partnership: The sui generis nature of PPP as a result of the holistic approach

    OpenAIRE

    Cvetković Predrag

    2014-01-01

    The holistic (comprehensive] approach to the methodological framework for the analysis of public-private partnership is essential presumption for the transformation of the public and private interests from the conflicting ones to the parallel and convergent ones. Private and public interests are to be regarded not as the divided particulars but as the element of the dynamics of PPP as a whole. The holistic approach facilitates interaction which brings new 'added values' in the exercise of the...

  17. Health-promoting schools: evidence for a holistic approach to promoting health and improving health literacy.

    Science.gov (United States)

    Lee, Albert

    2009-01-01

    Chronic diseases are now the major causes of death and disability worldwide, and non-communicable diseases (NCD) account for the majority of the global health burden. About half of premature deaths are related to health-risking behaviours that are often established during youth and extend to adulthood. While these diseases might not be curable, they are preventable. Prevention is possible when sustained actions are directed at individuals and families, as well as at the broader social, economic and cultural determinants of NCD. A 'life-course' approach to promoting healthy behaviour should begin early in life. The aim of this article is to discuss the impact of the 'health-promoting school' (HPS) on improvements in youth health. HPS can be described as a holistic, whole-school approach in which a broad health education curriculum is supported by the environment and ethos of the school. HPS moves beyond individual behavioural change to consider organizational and policy change such as improving the physical and social environment of the school, as well as its curricula and teaching and learning methods. A positive culture for health would facilitate higher levels of health literacy by helping individuals tackle the determinants of health better as they build the personal, cognitive and social skills for maintaining good health. There is reasonable evidence to demonstrate that the whole-school approach using the HPS framework is effective in improving health, ranging from physical activities and healthy eating to emotional health. Schools adopting the HPS framework have demonstrated changes in culture and organizational practice to become more conducive to health improvement. These schools were reported to have better school health policies, higher degrees of community participation, and a more hygienic environment than non-HPS schools, and students in these schools had a more positive health behaviour profile. Health promotion and disease prevention is essential to

  18. THE STRATEGY FOR CREATION OF THE MODERN CONCEPT OF INTEGRATIVE-HOLISTIC EDUCATION (A CASE STUDY OF MINING SCHOOLS OF THE URALS

    Directory of Open Access Journals (Sweden)

    N. K. Chapaev

    2017-01-01

    Full Text Available Introduction. The relevance of the problem under study is caused by the contradiction between the necessity of fundamentalization of education, raising it to the level of the requirements of integral human development and the deepening disintegration of all sides of his life, including vocational education.The aim of the present publication is philosophical and pedagogical reflection and development of mechanisms for mainstreaming integrative-holistic approach when building a hypothetical model of professional education, aimed at provision of strategic turn towards more balanced (dialectical approach to the traditional values of education. In particular, it concerns the experience of mining schools of the Urals.Methodology and research methods. A leading approach to the study of this problem is an integrative-holistic approach (PPI that can identify the holistic nature of the pedagogical system in which: a inter-transformation of cooperated parts occurs not at the expense of each other, but on behalf of each other part; b the existence of common points of contact between the cooperated components is complemented by the coexistence of the opposite, sometimes mutually exclusive sides of life; c the idea of the priority of the whole is in harmony with the idea of polycentrism.Results and scientific novelty. The study shows the failure of the monopoly of the prevailing doctrine of competence-based education as a means for the successful resolution of global problems of reintegration of human existence and therefore postulated the necessity of antinomization (diversification of education. The authors make the original hypothesis of the construction of the concept of vocational education on the basis of the reconstruction of experience of the mining schools of the Urals and prove the prospectivity of integrative-holistic strategy of reconstruction of educational experience in modern conditions. The system of technological and methodological support of

  19. The Green City Car. A holistic approach for NVH abatement of city cars

    OpenAIRE

    Bein, Thilo; Mayer, Dirk; Elliott, Steve; Ferrali, Leonardo; Casella, Mauro; Saemann, Ernst-Ulrich; Kropp, Wolfgang; Nielsen, Finn Kryger; Meschke, Jens; Pisano, Emanuel

    2014-01-01

    Pursuing the different passive and active concepts in a holistic approach, the FP7 project Green City Car demonstrates the feasibility of applying active systems to NVH-related problems light city cars from a system point-of view. During the project, a city car equipped with a small engine has been considered equipped with the latest technology in terms of safety aspects related to pedestrian’s impact and car-to-car compatibility, which are of major importance in an urban environment. The noi...

  20. Firstline treatment for chronic phase chronic myeloid leukemia patients should be based on a holistic approach.

    Science.gov (United States)

    Breccia, Massimo; Alimena, Giuliana

    2015-02-01

    New selective and more potent drugs for the cure of chronic phase chronic myeloid leukemia patients are now available: physicians in some countries must decide the best option, selecting one of the drugs available. What the main prognostic factors are in order to make this selection remains a matter of discussion. Introducing a 'holistic approach' for the first time in chronic myeloid leukemia, as practiced in other diseases, and looking at the patient in a complete picture, considering several variables, such as comorbidities, age, concomitant drugs, lifestyle and patient expectations, may be of help to understand, patient by patient, the best therapeutic strategy.

  1. Management of Tooth Wear: A Holistic, Dental, Medical, and Mental Healthcare Approach.

    Science.gov (United States)

    Ahmed, Khaled E

    2016-08-01

    Tooth wear is a condition that affects a substantial cohort of dental patients. It has a measurable impact on patients' satisfaction, and overall quality of life. Recently, with growing evidence, our understanding of the aetiology, progression, and management of tooth wear has evolved. The paper argues that pathological tooth wear should not be solely considered as a dental condition, but rather a dental manifestation of other mental and medical disorders. As such, successful management of tooth wear, and its underlying aetiology, requires a holistic, multidisciplinary management approach, involving dental, medical, and mental healthcare providers.

  2. Treat the brain and treat the periphery: toward a holistic approach to major depressive disorder.

    Science.gov (United States)

    Zheng, Xiao; Zhang, Xueli; Wang, Guangji; Hao, Haiping

    2015-05-01

    The limited medication for major depressive disorder (MDD) against an ever-rising disease burden presents an urgent need for therapeutic innovations. During recent years, studies looking at the systems regulation of mental health and disease have shown a remarkably powerful control of MDD by systemic signals. Meanwhile, the identification of a host of targets outside the brain opens the way to treat MDD by targeting systemic signals. We examine these emerging findings and consider the implications for current thinking regarding MDD pathogenesis and treatment. We highlight the opportunities and challenges of a periphery-targeting strategy and propose its incorporation into a holistic approach. Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. Surface Water Contamination and Los Alamos National Laboratory's Holistic Approach to Mitigation

    International Nuclear Information System (INIS)

    Katzman, D.; Veenis, S.; Reneau, S.

    2009-01-01

    A sediment and contaminant transport mitigation project is being implemented at Los Alamos National Laboratory. This effort is driven by a requirement from State of New Mexico regulators and is also in concert with efforts underway to support a surface-water diversion project by a Santa Fe, NM, public water utility. The effort is being implemented in a large geomorphically and hydrologically complex watershed. Rather than simply attempting to trap sediment in a retention basin, this effort uses a watershed-scale holistic approach with intent to promote watershed healing. (authors)

  4. A Holistic Approach to Climate and Health Research: Respiratory and Infectious Diseases

    Science.gov (United States)

    Asrar, G.; Alonoso, W.; McCormick, B.; Schuck-Paim, C.; Miller, M.

    2014-12-01

    The link between climate variability and change, especially extreme conditions, is well documented in both environmental and health literature. The focus of research in the recent past, and current studies, is to understand causal relationships between the disease agents and environmental conditions, based on post-hoc analysis of observed cases to develop predictive models for advance warning of public by health authorities. A combination of the isolated examination of individual diseases and routes of infection (e.g. respiratory system, skin, digestive tract, etc.) and reliance mostly on correlative evidence from past occurrences have restricted public health progress (e.g. compared to experimental evidence of the quantitative balance of different transmission routes) and the utility of knowledge gained from such studies (e.g. reliably predicting seasonal outbreaks is no longer an advance). We propose a shift from focusing on the prediction of individual disease pattern(s) to a more holistic identification and mitigation of broader vulnerabilities within the provision of public health. Such an approach has the potential to account for and reveal health vulnerabilities common to a broader range of health stresses, thus facilitating a more holistic response to health challenges. The human health fragilities associated with respiratory diseases caused by a combination of natural (i.e dust, pollen, etc.) and industrial particulates (i.e. soot, aerosols, etc.) and other infectious airborne agents, for example, and their adverse impact on human health such as respiratory, gastrointestinal, etc. is an ideal candidate for such a holistic approach to environment and health research.

  5. Introduction to the History and Current Status of Evidence-Based Korean Medicine: A Unique Integrated System of Allopathic and Holistic Medicine

    Directory of Open Access Journals (Sweden)

    Chang Shik Yin

    2014-01-01

    Full Text Available Objectives. Korean medicine, an integrated allopathic and traditional medicine, has developed unique characteristics and has been active in contributing to evidence-based medicine. Recent developments in Korean medicine have not been as well disseminated as traditional Chinese medicine. This introduction to recent developments in Korean medicine will draw attention to, and facilitate, the advancement of evidence-based complementary alternative medicine (CAM. Methods and Results. The history of and recent developments in Korean medicine as evidence-based medicine are explored through discussions on the development of a national standard classification of diseases and study reports, ranging from basic research to newly developed clinical therapies. A national standard classification of diseases has been developed and revised serially into an integrated classification of Western allopathic and traditional holistic medicine disease entities. Standard disease classifications offer a starting point for the reliable gathering of evidence and provide a representative example of the unique status of evidence-based Korean medicine as an integration of Western allopathic medicine and traditional holistic medicine. Conclusions. Recent developments in evidence-based Korean medicine show a unique development in evidence-based medicine, adopting both Western allopathic and holistic traditional medicine. It is expected that Korean medicine will continue to be an important contributor to evidence-based medicine, encompassing conventional and complementary approaches.

  6. Introduction to the history and current status of evidence-based korean medicine: a unique integrated system of allopathic and holistic medicine.

    Science.gov (United States)

    Yin, Chang Shik; Ko, Seong-Gyu

    2014-01-01

    Objectives. Korean medicine, an integrated allopathic and traditional medicine, has developed unique characteristics and has been active in contributing to evidence-based medicine. Recent developments in Korean medicine have not been as well disseminated as traditional Chinese medicine. This introduction to recent developments in Korean medicine will draw attention to, and facilitate, the advancement of evidence-based complementary alternative medicine (CAM). Methods and Results. The history of and recent developments in Korean medicine as evidence-based medicine are explored through discussions on the development of a national standard classification of diseases and study reports, ranging from basic research to newly developed clinical therapies. A national standard classification of diseases has been developed and revised serially into an integrated classification of Western allopathic and traditional holistic medicine disease entities. Standard disease classifications offer a starting point for the reliable gathering of evidence and provide a representative example of the unique status of evidence-based Korean medicine as an integration of Western allopathic medicine and traditional holistic medicine. Conclusions. Recent developments in evidence-based Korean medicine show a unique development in evidence-based medicine, adopting both Western allopathic and holistic traditional medicine. It is expected that Korean medicine will continue to be an important contributor to evidence-based medicine, encompassing conventional and complementary approaches.

  7. The concept of the holistic management as a new approach in the theory of management

    OpenAIRE

    Porvaznik, Jan

    2011-01-01

    The types of objects scientifically researched and the types of sciences used for research. The crisis of contemporary science. Classical and holistic management. The knowledge pillar of management, the application pillar of management, social pillar of management. Holistic intelligence (HQ), knowledge intelligence (KQ), application intelligence (AQ), social intelligence (SQ). Holistic management and its role in solving the contemporary problems of mankind.

  8. [New theory of holistic integrative physiology and medicine. II: New insight of the control and regulation of circulation].

    Science.gov (United States)

    Sun, Xing-guo

    2015-07-01

    The interpretation of control and regulation of circulatory parameters in traditional physiology has some limitations. Human being is an organic, circulatory control and regulation should involve all the systems. Based upon the theory of holistic integrative physiology and medicine, we approach to explain the circulatory control and regulation from its purpose. The main purpose of circulation is to maintain a stable metabolism of cells, i.e. transport oxygen (from lung) and nutrients (from gastrointestinal tract) to cells, and return carbon dioxide and metabolic products back for elimination. Based on this goal, all respiration and gastrointestinal digestion, absorption, urinary excretion, etc. are integrative together for regulation to maintain the supply-demand balance at any metabolic status of resting, exercise and sleep. So that, we can explain many existing problems and questions, for example: why and how the foramen ovale closed after birth; mechanism of Cheyne-Stokes respiration; blood flow redistribution during exercise; variabilities of systolic blood pressure, heart rate and autonomic tone. The circulatory control and regulation is the integration of all systems of the body.

  9. A holistic approach to improving indoor environmental quality: A case study

    International Nuclear Information System (INIS)

    Milam, J.A.; Kinser, D.E.

    1993-01-01

    One of the big six accounting firms recently consolidated several offices into a regional headquarters located in a southern metropolitan city. This regional headquarters involved seven floors totalling 187,000 square feet of tenant space in a new high rise building. The accounting firm realized that improving their employees' work environment would provide significant savings from increased worker productivity and reduced absenteeism. Therefore, the firm retained Environmental Design International (EDI) to provide consulting services to create and maintain an environmentally healthy office space. The creation of a healthy, productive and safe indoor environment involves a total, holistic approach to the various elements that affect indoor environmental quality (IEQ) in a building. A holistic approach requires detailed evaluation of all areas that impact indoor environmental quality and not just the more common review of HVAC systems. This case study shows that the optimization of a healthy indoor environment is an endless, all inclusive process: beginning with the initial construction material selections and environmental systems design; continuing through the construction and commissioning phases; and progressing to pro-active monitoring of IEQ parameters to protect the tenant's investment in a healthy, productive and safe indoor environment

  10. Israeli nurses' attitudes to the holistic approach to health and their use of complementary and alternative therapies.

    Science.gov (United States)

    Orkaby, Brurya; Greenberger, Chaya

    2015-03-01

    To examine nurses' attitudes to holistic and biomedical approaches to health care and the correlation between the two and to explore the extent of recommending and using complementary and alternative medicine (CAM) by nurses and its correlation with attitudes toward the holistic approach to care. In this cross-sectional correlational study, a structured questionnaire was completed anonymously by 213 Israeli hospital-based nurses from various departments. Nurses perceived both approaches as critical to optimal health care: a positive correlation emerged of attitudes to the two approaches. Nurses recommended and used CAM extensively; most therapies were recommended and/or used by 70% or more of the respondents. Nurses with more positive attitudes toward holistic care tended to recommend and use CAM to a greater extent. Biomedical and holistic approaches are perceived by nurses to coexist within nursing professional boundaries and form a broad basis for optimal health care. Nurses' attitudes to the holistic approach appear to promote recommendation and/or use of CAM in practice. More training in CAM should be offered in nursing educational frameworks and research should continue to establish evidence for CAM's effectiveness. © The Author(s) 2014.

  11. Using a holistic approach to assess the impact of engineered nanomaterials inducing toxicity in aquatic systems.

    Science.gov (United States)

    He, Xiaojia; Aker, Winfred G; Leszczynski, Jerzy; Hwang, Huey-Min

    2014-03-01

    In this report, we critically reviewed selected intrinsic physicochemical properties of engineered nanomaterials (ENMs) and their role in the interaction of the ENMs with the immediate surroundings in representative aquatic environments. The behavior of ENMs with respect to dynamic microenvironments at the nano-bio-eco interface level, and the resulting impact on their toxicity, fate, and exposure potential are elaborated. Based on this literature review, we conclude that a holistic approach is urgently needed to fulfill our knowledge gap regarding the safety of discharged ENMs. This comparative approach affords the capability to recognize and understand the potential hazards of ENMs and their toxicity mechanisms, and ultimately to establish a quantitative and reliable system to predict such outcomes. Copyright © 2014. Published by Elsevier B.V.

  12. A holistic and integrative approach to assessment for learning

    NARCIS (Netherlands)

    Vinke, A.A.; Hummels, C.C.M.

    2011-01-01

    Today's knowledge and information era faces graduates with complex, multi-layered issues in their professional lives. This requires them to be knowledge-managers rather than knowledge-owners. In order to perform in such a context graduates need to become autonomous, flexible and lifelong learners.

  13. Holistic feedback approach with video and peer discussion under teacher supervision.

    Science.gov (United States)

    Hunukumbure, Agra Dilshani; Smith, Susan F; Das, Saroj

    2017-09-29

    High quality feedback is vital to learning in medical education but many students and teachers have expressed dissatisfaction on current feedback practices. Lack of teachers' insight into students' feedback requirements may be a key, which might be addressed by giving control to the students with student led feedback practices. The conceptual framework was built on three dimensions of learning theory by Illeris and Vygotsky's zone of proximal development and scaffolding. We introduced a feedback session with self-reflection and peer feedback in the form of open discussion on video-recorded student performances under teacher's guidance. The aims of this qualitative study were to explore students' perception on this holistic feedback approach and to investigate ways of maximising effective feedback and learning. Semi-structured interviews were used to gather data which were evaluated using a thematic analytical approach. The participants were third year medical students of Imperial College London on clinical placements at Hillingdon Hospital. Video based self-reflection helped some students to identify mistakes in communication and technical skills of which they were unaware prior to the session. Those who were new to video feedback found their expected self-image different to that of their actual image on video, leading to some distress. However many also identified that mistakes were not unique to themselves through peer videos and learnt from both model performances and from each other's mistakes. Balancing honest feedback with empathy was a challenge for many during peer discussion. The teacher played a vital role in making the session a success by providing guidance and a supportive environment. This study has demonstrated many potential benefits of this holistic feedback approach with video based self-reflection and peer discussion with students engaging at a deeper cognitive level than the standard descriptive feedback.

  14. Replicated Computations Results (RCR) report for “A holistic approach for collaborative workload execution in volunteer clouds”

    DEFF Research Database (Denmark)

    Vandin, Andrea

    2018-01-01

    “A Holistic Approach for Collaborative Workload Execution in Volunteer Clouds” [3] proposes a novel approach to task scheduling in volunteer clouds. Volunteer clouds are decentralized cloud systems based on collaborative task execution, where clients voluntarily share their own unused computational...

  15. From Metaphors to Formalism: A Heuristic Approach to Holistic Assessments of Ecosystem Health.

    Science.gov (United States)

    Fock, Heino O; Kraus, Gerd

    2016-01-01

    Environmental policies employ metaphoric objectives such as ecosystem health, resilience and sustainable provision of ecosystem services, which influence corresponding sustainability assessments by means of normative settings such as assumptions on system description, indicator selection, aggregation of information and target setting. A heuristic approach is developed for sustainability assessments to avoid ambiguity and applications to the EU Marine Strategy Framework Directive (MSFD) and OSPAR assessments are presented. For MSFD, nineteen different assessment procedures have been proposed, but at present no agreed assessment procedure is available. The heuristic assessment framework is a functional-holistic approach comprising an ex-ante/ex-post assessment framework with specifically defined normative and systemic dimensions (EAEPNS). The outer normative dimension defines the ex-ante/ex-post framework, of which the latter branch delivers one measure of ecosystem health based on indicators and the former allows to account for the multi-dimensional nature of sustainability (social, economic, ecological) in terms of modeling approaches. For MSFD, the ex-ante/ex-post framework replaces the current distinction between assessments based on pressure and state descriptors. The ex-ante and the ex-post branch each comprise an inner normative and a systemic dimension. The inner normative dimension in the ex-post branch considers additive utility models and likelihood functions to standardize variables normalized with Bayesian modeling. Likelihood functions allow precautionary target setting. The ex-post systemic dimension considers a posteriori indicator selection by means of analysis of indicator space to avoid redundant indicator information as opposed to a priori indicator selection in deconstructive-structural approaches. Indicator information is expressed in terms of ecosystem variability by means of multivariate analysis procedures. The application to the OSPAR

  16. From Metaphors to Formalism: A Heuristic Approach to Holistic Assessments of Ecosystem Health

    Science.gov (United States)

    Kraus, Gerd

    2016-01-01

    Environmental policies employ metaphoric objectives such as ecosystem health, resilience and sustainable provision of ecosystem services, which influence corresponding sustainability assessments by means of normative settings such as assumptions on system description, indicator selection, aggregation of information and target setting. A heuristic approach is developed for sustainability assessments to avoid ambiguity and applications to the EU Marine Strategy Framework Directive (MSFD) and OSPAR assessments are presented. For MSFD, nineteen different assessment procedures have been proposed, but at present no agreed assessment procedure is available. The heuristic assessment framework is a functional-holistic approach comprising an ex-ante/ex-post assessment framework with specifically defined normative and systemic dimensions (EAEPNS). The outer normative dimension defines the ex-ante/ex-post framework, of which the latter branch delivers one measure of ecosystem health based on indicators and the former allows to account for the multi-dimensional nature of sustainability (social, economic, ecological) in terms of modeling approaches. For MSFD, the ex-ante/ex-post framework replaces the current distinction between assessments based on pressure and state descriptors. The ex-ante and the ex-post branch each comprise an inner normative and a systemic dimension. The inner normative dimension in the ex-post branch considers additive utility models and likelihood functions to standardize variables normalized with Bayesian modeling. Likelihood functions allow precautionary target setting. The ex-post systemic dimension considers a posteriori indicator selection by means of analysis of indicator space to avoid redundant indicator information as opposed to a priori indicator selection in deconstructive-structural approaches. Indicator information is expressed in terms of ecosystem variability by means of multivariate analysis procedures. The application to the OSPAR

  17. A holistic approach towards defined product attributes by Maillard-type food processing.

    Science.gov (United States)

    Davidek, Tomas; Illmann, Silke; Rytz, Andreas; Blank, Imre

    2013-07-01

    A fractional factorial experimental design was used to quantify the impact of process and recipe parameters on selected product attributes of extruded products (colour, viscosity, acrylamide, and the flavour marker 4-hydroxy-2,5-dimethyl-3(2H)-furanone, HDMF). The study has shown that recipe parameters (lysine, phosphate) can be used to modulate the HDMF level without changing the specific mechanical energy (SME) and consequently the texture of the product, while processing parameters (temperature, moisture) impact both HDMF and SME in parallel. Similarly, several parameters, including phosphate level, temperature and moisture, simultaneously impact both HDMF and acrylamide formation, while pH and addition of lysine showed different trends. Therefore, the latter two options can be used to mitigate acrylamide without a negative impact on flavour. Such a holistic approach has been shown as a powerful tool to optimize various product attributes upon food processing.

  18. A holistic approach to anesthesia-induced neurotoxicity and its implications for future mechanistic studies.

    Science.gov (United States)

    Zanghi, Christine N; Jevtovic-Todorovic, Vesna

    The year 2016 marked the 15th anniversary since anesthesia-induced developmental neurotoxicity and its resulting cognitive dysfunction were first described. Since that time, multiple scientific studies have supported these original findings and investigated possible mechanisms behind anesthesia-induced neurotoxicity. This paper reviews the existing mechanistic literature on anesthesia-induced neurotoxicity in the context of a holistic approach that emphasizes the importance of both neuronal and non-neuronal cells during early postnatal development. Sections are divided into key stages in early neural development; apoptosis, neurogenesis, migration, differentiation, synaptogenesis, gliogenesis, myelination and blood brain barrier/cerebrovasculature. In addition, the authors combine the established literature in the field of anesthesia-induced neurotoxicity with literature from other related scientific fields to speculate on the potential role of non-neuronal cells and to generate new future hypotheses for understanding anesthetic toxicity and its application to the practice of pediatric anesthesia. Copyright © 2017 Elsevier Inc. All rights reserved.

  19. Constructing a holistic approach to disaster risk reduction: the significance of focusing on vulnerability reduction.

    Science.gov (United States)

    Palliyaguru, Roshani; Amaratunga, Dilanthi; Baldry, David

    2014-01-01

    As a result of the increase in natural disaster losses, policy-makers, practitioners, and members of the research community around the world are seeking effective and efficient means of overcoming or minimising them. Although various theoretical constructs are beneficial to understanding the disaster phenomenon and the means of minimising losses, the disaster risk management process becomes less effective if theory and practice are set apart from one another. Consequently, this paper seeks to establish a relationship between two theoretical constructs, 'disaster risk reduction (DRR)' and 'vulnerability reduction', and to develop a holistic approach to DRR with particular reference to improving its applicability in practical settings. It is based on a literature review and on an overall understanding gained through two case studies of post-disaster infrastructure reconstruction projects in Sri Lanka and three expert interviews in Sri Lanka and the United Kingdom. © 2014 The Author(s). Disasters © Overseas Development Institute, 2014.

  20. Glocalized Production - A Holistic Approach for Future Manufacturing at The LEGO Group

    DEFF Research Database (Denmark)

    Hadar, Ronen

    2014-01-01

    ) and Rapid Manufacturing (RM). RMS is a manufacturing system that is designed for rapid changes. It is based on core characteristics such as modularity, convertibility, customized flexibility, etc.. RM is the use of Additive Manufacturing (AM –commonly referred to as 3D printing) for the production......Global production is changing. Changes in production paradigms, global competition, manufacturing technologies, and new mega trends such as individualization, inflict immense challenges on global manufacturers. A new holistic approach for facing supply chain and production challenges is proposed...... facilities, the establishment of production close to main markets, and the creation of a global network of independent factories and supply chains with local manufacturing. Doing so will potentially increase responsiveness, cut transportation costs, reduce complexity, enable production to demand rather than...

  1. Idiopathic pulmonary fibrosis: a holistic approach to disease management in the antifibrotic age.

    Science.gov (United States)

    Shaw, Jonathon; Marshall, Tracey; Morris, Helen; Hayton, Conal; Chaudhuri, Nazia

    2017-11-01

    Idiopathic pulmonary fibrosis (IPF) is the most common cause of interstitial lung disease (ILD) and carries a worse prognosis than many cancers. Until recently, there were no active treatment options available for patients with IPF, meaning palliation or lung transplantation in selected patients were the only options. The management of IPF has changed dramatically over the last decade with the advent of two antifibrotic agents; pirfenidone and nintedanib. These new agents have been shown to reduce decline in lung function and pirfenidone has been shown to reduce mortality. The changing landscape of IPF diagnosis and management present a number of issues that may be encountered including management of side effects related to antifibrotic therapy. This article aims to give an overview of the holistic approach to the management of patients with IPF, including antifibrotic management, symptom management and the invaluable role of the ILD specialist nurse.

  2. THE STRATEGY FOR CREATION OF THE MODERN CONCEPT OF INTEGRATIVE-HOLISTIC EDUCATION (A CASE STUDY OF MINING SCHOOLS OF THE URALS

    Directory of Open Access Journals (Sweden)

    N. K. Chapaev

    2017-01-01

    Full Text Available Introduction. The relevance of the problem under study is caused by the contradiction between the necessity of fundamentalization of education, raising it to the level of the requirements of integral human development and the deepening disintegration of all sides of his life, including vocational education.The aim of the present publication is philosophical and pedagogical reflection and development of mechanisms for mainstreaming integrative-holistic approach when building a hypothetical model of professional education, aimed at provision of strategic turn towards more balanced (dialectical approach to the traditional values of education. In particular, it concerns the experience of mining schools of the Urals.Methods. A leading approach to the study of this problem is an integrativeholistic approach (PPI that can identify the holistic nature of the pedagogical system in which: a inter-transformation of cooperated parts occurs not at the expense of each other, but on behalf of each other part; b the existence of common points of contact between the cooperated components is complemented by the coexistence of the opposite, sometimes mutually exclusive sides of life; c the idea of the priority of the whole is in harmony with the idea of polycentrism.Results and scientific novelty. The study shows the failure of the monopoly of the prevailing doctrine of competence-based education as a means for the successful resolution of global problems of reintegration of human existence and therefore postulated the necessity of antinomization (diversification of education. The authors make the original hypothesis of the construction of the concept of vocational education on the basis of the reconstruction of experience of the mining schools of the Urals and prove the prospectivity of integrative-holistic strategy of reconstruction of educational experience in modern conditions. The system of technological and methodological support of the

  3. A holistic approach to the environmental evaluation of food waste prevention.

    Science.gov (United States)

    Salemdeeb, Ramy; Font Vivanco, David; Al-Tabbaa, Abir; Zu Ermgassen, Erasmus K H J

    2017-01-01

    The environmental evaluation of food waste prevention is considered a challenging task due to the globalised nature of the food supply chain and the limitations of existing evaluation tools. The most significant of these is the rebound effect: the associated environmental burdens of substitutive consumption that arises as a result of economic savings made from food waste prevention. This study introduces a holistic approach to addressing these challenges, with a focus on greenhouse gas (GHG) emissions from household food waste in the UK. It uses a hybrid life-cycle assessment model coupled with a highly detailed multi-regional environmentally extended input output analysis to capture environmental impacts across the global food supply chain. The study also takes into consideration the rebound effect, which was modelled using a linear specification of an almost ideal demand system. The study finds that food waste prevention could lead to substantial reductions in GHG emissions in the order of 706-896kg CO 2 -eq. per tonne of food waste, with most of these savings (78%) occurring as a result of avoided food production overseas. The rebound effect may however reduce such GHG savings by up to 60%. These findings provide a deeper insight into our understanding of the environmental impacts of food waste prevention: the study demonstrates the need to adopt a holistic approach when developing food waste prevention policies in order to mitigate the rebound effect and highlight the importance of increasing efficiency across the global food supply chain, particularly in developing countries. Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. How Older Persons Perceive the Loss of Independence: The Need of a Holistic Approach to Frailty.

    Science.gov (United States)

    Escourrou, E; Cesari, M; Chicoulaa, B; Fougère, B; Vellas, B; Andrieu, S; Oustric, S

    2017-01-01

    Since 2004, the definition of the frailty syndrome has shifted from purely physical criteria to a more comprehensive consideration of the individual, including their psychosocial criteria. In this study, qualitative research methods were used as a complementary approach in order to enrich the existing quantitative results in this area. To understand the views of older persons on the risk of loss of independence. The study population comprised people over 75 years of age who were living at home in the south-west of France and were considered to be at risk of losing their independence. Data were collected using individual semi-structured in-depth interviews, accompanied by observations. Inductive analysis was carried out according to grounded theory methods. Fifteen individual interviews were conducted to achieve theoretical data saturation. Analysis of the content of the interviews revealed seven risk factors for the loss of independence: poor mental health, poor physical health, social isolation, no longer leaving the home, an unsuitable environment, unsuitable living conditions, and few resources. These results complement the purely physical approach to screening for the frailty syndrome and lead us to reconsider our screening approach to include a more holistic view of the older person and their circumstances.

  5. Introduction to solid mechanics an integrated approach

    CERN Document Server

    Lubliner, Jacob

    2017-01-01

    This expanded second edition presents in one text the concepts and processes covered in statics and mechanics of materials curricula following a systematic, topically integrated approach. Building on the novel pedagogy of fusing concepts covered in traditional undergraduate courses in rigid-body statics and deformable body mechanics, rather than simply grafting them together, this new edition develops further the authors’ very original treatment of solid mechanics with additional figures, an elaboration on selected solved problems, and additional text as well as a new subsection on viscoelasticity in response to students’ feedback. Introduction to Solid Mechanics: An Integrated Approach, Second Edition, offers a holistic treatment of the depth and breadth of solid mechanics and the inter-relationships of its underlying concepts. Proceeding from first principles to applications, the book stands as a whole greater than the sum of its parts.  .

  6. Evaluating the effectiveness of restoring longitudinal connectivity for stream fish communities: towards a more holistic approach.

    Science.gov (United States)

    Tummers, Jeroen S; Hudson, Steve; Lucas, Martyn C

    2016-11-01

    A more holistic approach towards testing longitudinal connectivity restoration is needed in order to establish that intended ecological functions of such restoration are achieved. We illustrate the use of a multi-method scheme to evaluate the effectiveness of 'nature-like' connectivity restoration for stream fish communities in the River Deerness, NE England. Electric-fishing, capture-mark-recapture, PIT telemetry and radio-telemetry were used to measure fish community composition, dispersal, fishway efficiency and upstream migration respectively. For measuring passage and dispersal, our rationale was to evaluate a wide size range of strong swimmers (exemplified by brown trout Salmo trutta) and weak swimmers (exemplified by bullhead Cottus perifretum) in situ in the stream ecosystem. Radio-tracking of adult trout during the spawning migration showed that passage efficiency at each of five connectivity-restored sites was 81.3-100%. Unaltered (experimental control) structures on the migration route had a bottle-neck effect on upstream migration, especially during low flows. However, even during low flows, displaced PIT tagged juvenile trout (total n=153) exhibited a passage efficiency of 70.1-93.1% at two nature-like passes. In mark-recapture experiments juvenile brown trout and bullhead tagged (total n=5303) succeeded in dispersing upstream more often at most structures following obstacle modification, but not at the two control sites, based on a Laplace kernel modelling approach of observed dispersal distance and barrier traverses. Medium-term post-restoration data (2-3years) showed that the fish assemblage remained similar at five of six connectivity-restored sites and two control sites, but at one connectivity-restored headwater site previously inhabited by trout only, three native non-salmonid species colonized. We conclude that stream habitat reconnection should support free movement of a wide range of species and life stages, wherever retention of such

  7. Integration a functional approach

    CERN Document Server

    Bichteler, Klaus

    1998-01-01

    This book covers Lebesgue integration and its generalizations from Daniell's point of view, modified by the use of seminorms. Integrating functions rather than measuring sets is posited as the main purpose of measure theory. From this point of view Lebesgue's integral can be had as a rather straightforward, even simplistic, extension of Riemann's integral; and its aims, definitions, and procedures can be motivated at an elementary level. The notion of measurability, for example, is suggested by Littlewood's observations rather than being conveyed authoritatively through definitions of (sigma)-algebras and good-cut-conditions, the latter of which are hard to justify and thus appear mysterious, even nettlesome, to the beginner. The approach taken provides the additional benefit of cutting the labor in half. The use of seminorms, ubiquitous in modern analysis, speeds things up even further. The book is intended for the reader who has some experience with proofs, a beginning graduate student for example. It might...

  8. Reliability of objects in aerospace technologies and beyond: Holistic risk management approach

    Science.gov (United States)

    Shai, Yair; Ingman, D.; Suhir, E.

    A “ high level” , deductive-reasoning-based (“ holistic” ), approach is aimed at the direct analysis of the behavior of a system as a whole, rather than with an attempt to understand the system's behavior by conducting first a “ low level” , inductive-reasoning-based, analysis of the behavior and the contributions of the system's elements. The holistic view on treatment is widely accepted in medical practice, and “ holistic health” concept upholds that all the aspects of people's needs (psychological, physical or social), should be seen as a whole, and that a disease is caused by the combined effect of physical, emotional, spiritual, social and environmental imbalances. Holistic reasoning is applied in our analysis to model the behavior of engineering products (“ species” ) subjected to various economic, marketing, and reliability “ health” factors. Vehicular products (cars, aircraft, boats, etc.), e.g., might be still robust enough, but could be out-of-date, or functionally obsolete, or their further use might be viewed as unjustifiably expensive. High-level-performance functions (HLPF) are the essential feature of the approach. HLPFs are, in effect, “ signatures” of the “ species” of interest. The HLPFs describe, in a “ holistic” , and certainly in a probabilistic, way, numerous complex multi-dependable relations among the representatives of the “ species” under consideration. ; umerous inter-related “ stresses” , both actual (“ physical” ) and nonphysical, which affect the probabilistic predictions are inherently being taken into account by the HLPFs. There is no need, and might even be counter-productive, to conduct tedious, time- and labor-consuming experimentations and to invest significant amount of time and resources to accumulate “ representative statistics” to predict - he governing probabilistic characteristics of the system behavior, such as, e.g., life expectancy of a particular type of products.

  9. A Comparison of Three Holistic Approaches to Health: One Health, EcoHealth, and Planetary Health

    Directory of Open Access Journals (Sweden)

    Henrik Lerner

    2017-09-01

    Full Text Available Several holistic and interdisciplinary approaches exist to safeguard health. Three of the most influential concepts at the moment, One Health, EcoHealth, and Planetary Health, are analyzed in this paper, revealing similarities and differences at the theoretical conceptual level. These approaches may appear synonymous, as they all promote the underlying assumption of humans and other animals sharing the same planet and the same environmental challenges, infections and infectious agents as well as other aspects of physical—and possibly mental—health. However, we would like to illuminate the differences between these three concepts or approaches, and how the choice of terms may, deliberately or involuntary, signal the focus, and underlying values of the approaches. In this paper, we have chosen some proposed and well-known suggestions of definitions. In our theoretical analysis, we will focus on at least two areas. These are (1 the value of the potential scientific areas which could be included and (2 core values present within the approach. In the first area, our main concern is whether the approaches are interdisciplinary and whether the core scientific areas are assigned equal importance. For the second area, which is rather wide, we analyze core values such as biodiversity, health, and how one values humans, animals, and ecosystems. One Health has been described as either a narrow approach combining public health and veterinary medicine or as a wide approach as in the wide-spread “umbrella” depiction including both scientific fields, core concepts, and interdisciplinary research areas. In both cases, however, safeguarding the health of vertebrates is usually in focus although ecosystems are also included in the model. The EcoHealth approach seems to have more of a biodiversity focus, with an emphasis on all living creatures, implying that parasites, unicellular organisms, and possibly also viruses have a value and should be protected

  10. A Comparison of Three Holistic Approaches to Health: One Health, EcoHealth, and Planetary Health.

    Science.gov (United States)

    Lerner, Henrik; Berg, Charlotte

    2017-01-01

    Several holistic and interdisciplinary approaches exist to safeguard health. Three of the most influential concepts at the moment, One Health, EcoHealth, and Planetary Health, are analyzed in this paper, revealing similarities and differences at the theoretical conceptual level. These approaches may appear synonymous, as they all promote the underlying assumption of humans and other animals sharing the same planet and the same environmental challenges, infections and infectious agents as well as other aspects of physical-and possibly mental-health. However, we would like to illuminate the differences between these three concepts or approaches, and how the choice of terms may, deliberately or involuntary, signal the focus, and underlying values of the approaches. In this paper, we have chosen some proposed and well-known suggestions of definitions. In our theoretical analysis, we will focus on at least two areas. These are (1) the value of the potential scientific areas which could be included and (2) core values present within the approach. In the first area, our main concern is whether the approaches are interdisciplinary and whether the core scientific areas are assigned equal importance. For the second area, which is rather wide, we analyze core values such as biodiversity, health, and how one values humans, animals, and ecosystems. One Health has been described as either a narrow approach combining public health and veterinary medicine or as a wide approach as in the wide-spread "umbrella" depiction including both scientific fields, core concepts, and interdisciplinary research areas. In both cases, however, safeguarding the health of vertebrates is usually in focus although ecosystems are also included in the model. The EcoHealth approach seems to have more of a biodiversity focus, with an emphasis on all living creatures, implying that parasites, unicellular organisms, and possibly also viruses have a value and should be protected. Planetary Health, on the

  11. Geohazards in the IYPE: An Example of a Holistic Approach to Achieving a Vision (Invited)

    Science.gov (United States)

    Woodfork, L. D.; Eder, W.; Janoschek, W.

    2009-12-01

    The International Year of Planet Earth (IYPE), a triennium (2007 - 2009), is a joint initiative between UNESCO and the IUGS. The central year, 2008, was proclaimed by the UN General Assembly to be The International Year of Planet Earth (for complete details, visit www.yearofplanetearth.org). Two major foci comprise the IYPE: a science/research initiative on 10 broad, multidisciplinary, socially relevant programs, one of which was Hazards. The second was outreach/public education to make the science/research relevant to a broader audience, including the general public, and in particular, decision makers at all levels of government through the local, state/province, national, and international levels. The vision of IYPE was to make its subtitle, "Earth Sciences for Society," not just a slogan but an influential global reality. Geohazards, however defined, are pervasive global phenomena ranging from small nuisance situations, to those with significant financial considerations, to huge, catastrophic events involving enormous loss of life and tremendous financial loss. Clearly, to attempt to effectively deal with geohazards in modern society, we must (1) Maximize public awareness of the appreciation of the danger involved in various situations (2) Minimize the risk through appropriate public policy and personal responsibility (3) Mitigate the danger and damage that might occur despite our best efforts to accomplish (1) and (2). Over the past three years, the IYPE has pursued a holistic approach to dealing with geohazards, involving science/research and outreach/education through the activities of national committees for the IYPE in 80 countries around the globe. Now as the IYPE draws rapidly to a close at the end of this calendar year, we have accomplished much using this holistic approach toward our noble vision of making "Earth Sciences for Society" a reality. Although a significant record of accomplishment and a legacy of the IYPE remain, in my view, much still

  12. HOLISTIC APPROACH FOR ASSESSING THE PRESENCE AND POTENTIAL IMPACTS OF WATERBORNE ENVIRONMENTAL CONTAMINANTS

    Science.gov (United States)

    As an integral part of our continuing research in environmental quality assessment approaches, we have developed a variety of passive integrative sampling devices widely applicable for use in defining the presence and potential impacts of a broad array of contaminants. The semipe...

  13. A HOLISTIC APPROACH OF RELATIONSHIP MARKETING IN LAUNCHING LUXURY NEW PRODUCTS

    Directory of Open Access Journals (Sweden)

    Mihoc Florin

    2009-05-01

    Full Text Available On the basis of increased complexity of the exchange mechanism, at the beginning of the third millennium the contemporary marketing suffers some physiognomic changes. Holistic orientation of the contemporary marketing is imposed by the new dimensions the

  14. A Study of Holistic and Subskill Instructional Approaches to Reading Comprehension.

    Science.gov (United States)

    Vacca, Richard T.

    1980-01-01

    In a six-week study involving seventh- to ninth-grade students in a summer corrective reading program, neither the holistic nor the subskill treatment had a significant advantage in improving student reading comprehension or attitude toward reading. (JT)

  15. A Holistic Approach to Manufacturing System Design in the Defense Aerospace Industry

    National Research Council Canada - National Science Library

    Vaughn, Amanda

    2002-01-01

    .... Also, manufacturing systems are complex systems that need to be carefully designed in a holistic manner and there are shortcomings with available tools and methods to assist in the design of these systems...

  16. Integrating the Ontological, Epistemological, and Sociocultural Aspects: A Holistic View of Teacher Education

    Science.gov (United States)

    Huang, Teng

    2016-01-01

    The three aspects of teacher change--ontological, epistemological, and sociocultural--are traditionally regarded as independent. Usually only the epistemological aspect is highlighted in formal teacher education. In this paper, I argue that a holistic and interdependent view of these aspects is needed. Thus, this paper aims to explore the process…

  17. The work ability divide: holistic and reductionistic approaches in Swedish interdisciplinary rehabilitation teams.

    Science.gov (United States)

    Ståhl, Christian; Svensson, Tommy; Petersson, Gunilla; Ekberg, Kerstin

    2009-09-01

    Stakeholder cooperation in return to work has been increasingly emphasised in research, while studies on how such cooperation works in practise are scarce. This article investigates the relationship between professionals in Swedish interdisciplinary rehabilitation teams, and the aim of the article is to determine the participants' definitions and uses of the concept of work ability. The methods chosen were individual interviews with primary health care centre managers and focus groups with twelve interdisciplinary teams including social insurance officers, physicians, physiotherapists, occupational therapists, medical social workers and coordinators. The results show that the teams have had problems with reaching a common understanding of their task, due to an inherent tension between the stakeholders. This tension is primarily a result of two factors: divergent perspectives on work ability between the health professionals and the Social Insurance Agency, and different approaches to cooperative work among physicians. Health professionals share a holistic view on work ability, relating it to a variety of factors. Social insurance officers, on the other hand, represent a reductionistic stance, where work ability is reduced to medical status. Assessments of work ability therefore tend to become a negotiation between insurance officers and physicians. A suggestion from the study is that the teams, with proper education, could be used as an arena for planning and coordinating return-to-work, which would strengthen their potential in managing the prevention of work disability.

  18. A holistic approach to ZigBee performance enhancement for home automation networks.

    Science.gov (United States)

    Betzler, August; Gomez, Carles; Demirkol, Ilker; Paradells, Josep

    2014-08-14

    Wireless home automation networks are gaining importance for smart homes. In this ambit, ZigBee networks play an important role. The ZigBee specification defines a default set of protocol stack parameters and mechanisms that is further refined by the ZigBee Home Automation application profile. In a holistic approach, we analyze how the network performance is affected with the tuning of parameters and mechanisms across multiple layers of the ZigBee protocol stack and investigate possible performance gains by implementing and testing alternative settings. The evaluations are carried out in a testbed of 57 TelosB motes. The results show that considerable performance improvements can be achieved by using alternative protocol stack configurations. From these results, we derive two improved protocol stack configurations for ZigBee wireless home automation networks that are validated in various network scenarios. In our experiments, these improved configurations yield a relative packet delivery ratio increase of up to 33.6%, a delay decrease of up to 66.6% and an improvement of the energy efficiency for battery powered devices of up to 48.7%, obtainable without incurring any overhead to the network.

  19. A Holistic Approach to ZigBee Performance Enhancement for Home Automation Networks

    Science.gov (United States)

    Betzler, August; Gomez, Carles; Demirkol, Ilker; Paradells, Josep

    2014-01-01

    Wireless home automation networks are gaining importance for smart homes. In this ambit, ZigBee networks play an important role. The ZigBee specification defines a default set of protocol stack parameters and mechanisms that is further refined by the ZigBee Home Automation application profile. In a holistic approach, we analyze how the network performance is affected with the tuning of parameters and mechanisms across multiple layers of the ZigBee protocol stack and investigate possible performance gains by implementing and testing alternative settings. The evaluations are carried out in a testbed of 57 TelosB motes. The results show that considerable performance improvements can be achieved by using alternative protocol stack configurations. From these results, we derive two improved protocol stack configurations for ZigBee wireless home automation networks that are validated in various network scenarios. In our experiments, these improved configurations yield a relative packet delivery ratio increase of up to 33.6%, a delay decrease of up to 66.6% and an improvement of the energy efficiency for battery powered devices of up to 48.7%, obtainable without incurring any overhead to the network. PMID:25196004

  20. A Holistic Approach to ZigBee Performance Enhancement for Home Automation Networks

    Directory of Open Access Journals (Sweden)

    August Betzler

    2014-08-01

    Full Text Available Wireless home automation networks are gaining importance for smart homes. In this ambit, ZigBee networks play an important role. The ZigBee specification defines a default set of protocol stack parameters and mechanisms that is further refined by the ZigBee Home Automation application profile. In a holistic approach, we analyze how the network performance is affected with the tuning of parameters and mechanisms across multiple layers of the ZigBee protocol stack and investigate possible performance gains by implementing and testing alternative settings. The evaluations are carried out in a testbed of 57 TelosB motes. The results show that considerable performance improvements can be achieved by using alternative protocol stack configurations. From these results, we derive two improved protocol stack configurations for ZigBee wireless home automation networks that are validated in various network scenarios. In our experiments, these improved configurations yield a relative packet delivery ratio increase of up to 33.6%, a delay decrease of up to 66.6% and an improvement of the energy efficiency for battery powered devices of up to 48.7%, obtainable without incurring any overhead to the network.

  1. Holistic approach for overlay and edge placement error to meet the 5nm technology node requirements

    Science.gov (United States)

    Mulkens, Jan; Slachter, Bram; Kubis, Michael; Tel, Wim; Hinnen, Paul; Maslow, Mark; Dillen, Harm; Ma, Eric; Chou, Kevin; Liu, Xuedong; Ren, Weiming; Hu, Xuerang; Wang, Fei; Liu, Kevin

    2018-03-01

    In this paper, we discuss the metrology methods and error budget that describe the edge placement error (EPE). EPE quantifies the pattern fidelity of a device structure made in a multi-patterning scheme. Here the pattern is the result of a sequence of lithography and etching steps, and consequently the contour of the final pattern contains error sources of the different process steps. EPE is computed by combining optical and ebeam metrology data. We show that high NA optical scatterometer can be used to densely measure in device CD and overlay errors. Large field e-beam system enables massive CD metrology which is used to characterize the local CD error. Local CD distribution needs to be characterized beyond 6 sigma, and requires high throughput e-beam system. We present in this paper the first images of a multi-beam e-beam inspection system. We discuss our holistic patterning optimization approach to understand and minimize the EPE of the final pattern. As a use case, we evaluated a 5-nm logic patterning process based on Self-Aligned-QuadruplePatterning (SAQP) using ArF lithography, combined with line cut exposures using EUV lithography.

  2. A Holistic Approach to Antiaging as an Adjunct to Antiaging Procedures: A Review of the Literature.

    Science.gov (United States)

    Saluja, Sandeep S; Fabi, Sabrina G

    2017-04-01

    Aging is a multifactorial process and depends on both intrinsic and extrinsic factors. Procedural options for diminishing signs of intrinsic aging and cosmetic rejuvenation have expanded dramatically. However, less attention is paid to counseling patients on options for mitigating extrinsic factors related to aging. The objective of this study was to review changes that occur with intrinsic and extrinsic aging, and provide evidence-based holistic counseling recommendations that can be used synergistically with aesthetic procedures to maximize antiaging interventions. A PubMed search was conducted for articles on intrinsic and extrinsic aging as it relates to skin, fat, muscle, and bone. Key clinical trials and studies on the effect of diet, hormones, exercise, sleep, stress, dental hygiene, smoking, pollution, and oxidative stress on the aging process are reviewed, and treatment recommendations are summarized based on available evidence. Conventional cosmetic procedures and cosmeceuticals work together with nutritious diet, exercise, dental hygiene, hormonal balance, stress reduction, smoking and pollution avoidance, and healthy sleep patterns for a better effect on antiaging. A combination approach of multiple nonsurgical modalities along with healthy lifestyle recommendations to minimize intrinsic and extrinsic aging factors allows cosmetic practitioners to target multiple facets of aging concurrently and maximize the aesthetic interventions cosmetic dermatologists/practitioners provide.

  3. Donor-derived infections in solid organ transplant patients: toward a holistic approach.

    Science.gov (United States)

    Benamu, Esther; Wolfe, Cameron R; Montoya, José G

    2017-08-01

    Solid organ demand far exceeds organ supply. Strategies to increase the donor pool include the liberalization of selection criteria without increasing the risk of unexpected donor-derived infection (DDI), a rare complication of transplantation carrying high morbidity and mortality. We review the challenging aspects in the prevention of DDI, focusing on the complexities of data sharing and efficient communication and the role infectious diseases specialists play in the process. Advances in donor screening, transmission recognition and reporting allow for a better estimation of the risk of DDI. However, there is great variability in the frequency and methods with which organ procurement organizations report transmission events.Moreover, the Scientific Registry of Transplant Recipients provides limited donor and recipient outcome infectious diseases related data. Infectious disease contribution to the allocation process has been found to improve organ donation efficiency and communication between involved parties. Although communication gaps are strongly associated with infection transmission (relative risk 2.36%, confidence interval 1.48-3.78), effective communication minimizes or prevents infection in transplant recipients (X(1) 13.13, P = 0.0003). Prospective research is still required to define optimal screening protocols and further prevent transmission of infection. A holistic approach is likely to result in enhanced transplantation safety. Toward this goal, development of standards of investigation; improvement in reporting and data sharing; and strategies ensuring coordinated and rapid communication among parties involved in the allocation process need to be pursued.

  4. Immune competence assessment in marine medaka (Orzyias melastigma)-a holistic approach for immunotoxicology.

    Science.gov (United States)

    Ye, Roy R; Peterson, Drew R; Seemann, Frauke; Kitamura, Shin-Ichi; Lee, J S; Lau, Terrance C K; Tsui, Stephen K W; Au, Doris W T

    2017-12-01

    Many anthropogenic pollutants in coastal marine environments can induce immune impairments in wild fish and reduce their survival fitness. There is a pressing need to establish sensitive and high throughput in vivo tools to systematically evaluate the immunosuppressive effects of contaminants in marine teleosts. This study reviewed a battery of in vivo immune function detection technologies established for different biological hierarchies at molecular (immune function pathways and genes by next generation sequencing (NGS)), cellular (leukocytes profiles by flow cytometry), tissues/organ system (whole adult histo-array), and organism (host resistance assays (HRAs)) levels, to assess the immune competence of marine medaka Oryzias melastigma. This approach enables a holistic assessment of fish immune competence under different chemical exposure or environmental scenarios. The data obtained will also be useful to unravel the underlying immunotoxic mechanisms. Intriguingly, NGS analysis of hepatic immune gene expression profiles (male > female) are in support of the bacterial HRA findings, in which infection-induced mortality was consistently higher in females than in males. As such, reproductive stages and gender-specific responses must be taken into consideration when assessing the risk of immunotoxicants in the aquatic environment. The distinct phenotypic sexual dimorphism and short generation time (3 months) of marine medaka offer additional advantages for sex-related immunotoxicological investigation.

  5. Outlining the psychopathology behind a case of conversion syndrome: Is a holistic approach beneficial?

    Science.gov (United States)

    Aquilina, Francesca Falzon; Fondacaro, Daniel Vella

    2016-03-01

    Conversion disorder refers to a set of symptoms where no relevant organic cause is found. These include sensory/motor disturbances, and other neurological symptoms, such as pseudoseizures. Patients with this condition may, by having it, achieve a primary or secondary gain. The condition should be diagnosed when all the relevant investigations are inconclusive. In this case, we use the bio-psycho-social model for the interpretation and guidance of treatment. We also demonstrate how a holistic approach is beneficial when it comes to a multi-dimensional interpretation of such a case. This review outlines a case of a patient with several neurological and orthopedic problems who failed to improve with several treatment plans and surgical interventions. After several years of medical and surgical consultations, a thorough analysis by psychiatrists was made, resulting in a diagnosis of conversion syndrome. The patient gradually improved on psychiatric treatment, including psychotherapy, and with the necessary psychiatric follow-ups. © 2016 The Institute of Psychology, Chinese Academy of Sciences and John Wiley & Sons Australia, Ltd.

  6. Holistic approach to human health and disease: life circumstances and inner processing.

    Science.gov (United States)

    Tomljenović, Andrea

    2014-06-01

    Human body is dinamic, energetic system under the influences of food intake, environment, interpersonal relationships, inheritance, culture and human activities. The environmental and psychosocioeconomic factors affect the individual's health altering the performance of biological systems effecting disease risk and disease progression. The concerns in modern society are more and more devoted to stress and its influences on health. Life span is extended but the quality of life, well-being and productivity usually do not follow that extention. Body is a flow of energy and dynamic communications with inside and outside environment. The way to improve health is to address its social determinants. Only in sinergy the questions about disease and health could be better understood. It is not enough to diagnose illness, important is to diagnose circumstances and environmental influences that consequently lead to disease. Emotional disruptions make base for physical disruptions. Social gradient and stress involving personal life and work is a significant factor in physical and mental illness. The best indicator of the successful social policy result is the sense of well-being of the inhabitants. Holistic approach to a patient and discussions about the influences in patient's life can lead to a better health outcome. Anthropology studies people's habits, means and conditions of life and can be the bridge between the medicine and the life circumstances that put people's health at risk providing important insights into health and disease and assist in public health policies, preventive measures and health improvement of the populations.

  7. Total organic carbon, an important tool in an holistic approach to hydrocarbon source fingerprinting

    Energy Technology Data Exchange (ETDEWEB)

    Boehm, P.D.; Burns, W.A.; Page, D.S.; Bence, A.E.; Mankiewicz, P.J.; Brown, J.S.; Douglas, G.S. [Battelle Member Inst., Waltham, MA (United States)

    2002-07-01

    The identification and allocation of multiple hydrocarbon sources in marine sediments is best achieved using an holistic approach. Total organic carbon (TOC) is one important tool that can constrain the contributions of specific sources and rule out incorrect source allocations in cases where inputs are dominated by fossil organic carbon. In a study of the benthic sediments from Prince William Sound (PWS) and the Gulf of Alaska (GOA), we find excellent agreement between measured TOC and TOC calculated from hydrocarbon fingerprint matches of polycyclic aromatic hydrocarbons (PAH) and chemical biomarkers. Confirmation by two such independent source indicators (TOC and fingerprint matches) provides evidence that source allocations determined by the fingerprint matches are robust and that the major TOC sources have been correctly identified. Fingerprint matches quantify the hydrocarbon contributions of various sources to the benthic sediments and the degree of hydrocarbon winnowing by waves and currents. TOC contents are then calculated using source allocation results from fingerprint matches and the TOCs of contributing sources. Comparisons of the actual sediment TOC values and those calculated from source allocation support our earlier published findings that the natural petrogenic hydrocarbon background in sediments in this area comes from eroding Tertiary shales and associated oil seeps along the northern GOA coast and exclude thermally mature area coals from being important contributors to the PWS background due to their high TOC content.

  8. A holistic approach to thermodynamic analysis of photo-thermo-electrical processes in a photovoltaic cell

    International Nuclear Information System (INIS)

    Bicer, Yusuf; Dincer, Ibrahim; Zamfirescu, Calin

    2016-01-01

    Highlights: • A novel approach for energy and exergy analyses of a photovoltaic cell is presented. • Photonic, thermal and electrical sub-processes are identified. • The irreversibilities caused by the photo-thermo-electrical processes are assessed. • Energy and exergy efficiencies are determined for comparison purposes. - Abstract: In this study, a novel approach for energy and exergy analyses of a photovoltaic (PV) cell is presented, and the exergy destructions within the relevant optical, thermal and electrical processes are quantified. The present study uses a holistic approach to cover all processes and their interactions inside a PV cell; such as photonic: photons transmission, reflection and spectral absorption, background (blackbody) radiation emission at cell temperature; electrical: electron excitation to create a photocurrent, electron-hole recombination, electrical power transmission to an external load; and thermal: internal heat generation by shunt and series resistances, and heat dissipation by conduction-convection. A physical model which considers the highly complex interaction and interdependence among these processes is introduced based on energy and exergy balances completed by writing various constitutive equations, including correlations for the convective heat transfer coefficient and the photocurrent dependence of the spectral distribution of the quantum efficiency. The irreversibilities caused by the processes are assessed in terms of their relative magnitudes of the exergy destructions. The largest exergy destruction occurs in PV generator-photo current generation process followed by wafer-light absorption process. The overall energy and exergy efficiencies are then determined based on the novel model for seven different atmospheric and ecological conditions. The lowest and highest exergy efficiencies of the PV cell are calculated as 9.3% and 14% for two sample locations as Oshawa in Canada and Emirdag in Turkey, respectively

  9. Holistic approach to design and implementation of a medical teleconsultation workspace.

    Science.gov (United States)

    Czekierda, Łukasz; Malawski, Filip; Wyszkowski, Przemysław

    2015-10-01

    While there are many state-of-the-art approaches to introducing telemedical services in the area of medical imaging, it is hard to point to studies which would address all relevant aspects in a complete and comprehensive manner. In this paper we describe our approach to design and implementation of a universal platform for imaging medicine which is based on our longstanding experience in this area. We claim it is holistic, because, contrary to most of the available studies it addresses all aspects related to creation and utilization of a medical teleconsultation workspace. We present an extensive analysis of requirements, including possible usage scenarios, user needs, organizational and security issues and infrastructure components. We enumerate and analyze multiple usage scenarios related to medical imaging data in treatment, research and educational applications - with typical teleconsultations treated as just one of many possible options. Certain phases common to all these scenarios have been identified, with the resulting classification distinguishing several modes of operation (local vs. remote, collaborative vs. non-interactive etc.). On this basis we propose a system architecture which addresses all of the identified requirements, applying two key concepts: Service Oriented Architecture (SOA) and Virtual Organizations (VO). The SOA paradigm allows us to decompose the functionality of the system into several distinct building blocks, ensuring flexibility and reliability. The VO paradigm defines the cooperation model for all participating healthcare institutions. Our approach is validated by an ICT platform called TeleDICOM II which implements the proposed architecture. All of its main elements are described in detail and cross-checked against the listed requirements. A case study presents the role and usage of the platform in a specific scenario. Finally, our platform is compared with similar systems described into-date studies and available on the market

  10. Clinical Holistic Medicine: Holistic Rehabilitation

    Directory of Open Access Journals (Sweden)

    Søren Ventegodt

    2005-01-01

    Full Text Available Quality of life, health, and ability are often lost at the same time and most often in one decaying existential movement over 5 or 10 years. This “lost life” is mostly too slow to be felt as life threatening, but once awakened to reality, it provokes the deepest of fears in patients: the fear of death itself and destruction of our mere existence. The horrible experience of having “lost life””, often without even noticing how it happened, can be turned into a strong motivation for improvement. Personal development is about finding the life deeply hidden within in order to induce revitalization and rehabilitation. Rehabilitation is about philosophy of life with the integration of the repressed painful feelings and emotions from the past and the letting go of the associated negative beliefs and decisions. The holistic medical toolbox builds on existential theories (the quality of life theories, the life mission theory, the theory of character, the theory of talent, and the holistic process theory and seems to have the power to rehabilitate the purpose of life, the character of the person, and fundamental existential dimensions of man: (1 love; (2 strength of mind, feelings, and body; and 3 joy, gender, and sexuality; allowing the person once again to express and realize his talents and full potential. The principles of rehabilitation are not very different from other healing, but the task is often more demanding for the holistic physician as the motivation and resources often are very low and the treatment can take many years.

  11. Integrated and holistic suitability assessment of recycling options for masonry rubble

    Science.gov (United States)

    Herbst, T.; Rübner, K.; Meng, B.

    2012-04-01

    constraints lead to a subordinated utilization on a rather low application level (downcycling). However, masonry rubble should also be recycled on a higher level (upcycling) in the future. For this purpose, an integrated and holistic but also practically oriented methodology for the suitability assessment of different recycling applications for masonry rubble is developed for a PhD currently. The suitability assessment includes the simultaneous evaluation of technical, economical and ecological aspects. Therefore, all recycling phases (demolition, processing, re-use) and the main kinds of masonry units (sorted or mixed) with their specific properties have to be considered.

  12. From a Reductionist to a Holistic Approach in Preventive Nutrition to Define New and More Ethical Paradigms.

    Science.gov (United States)

    Fardet, Anthony; Rock, Edmond

    2015-10-28

    This concept paper intends to define four new paradigms for improving nutrition research. First, the consequences of applying a reductionist versus a holistic approach to nutrition science will be discussed. The need for a more focused preventive nutrition approach, as opposed to a curative one, will then be presented on the basis of the 'healthy core metabolism' concept. This will lead us to propose a new classification of food products based on processing for future epidemiological studies. As a result of applying the holistic approach, health food potential will be redefined based on both food structure and nutrient density. These new paradigms should help define a more ethical preventive nutrition for humans to improve public recommendations while preserving the environment.

  13. A holistic approach to food safety risks: Food fraud as an example.

    Science.gov (United States)

    Marvin, Hans J P; Bouzembrak, Yamine; Janssen, Esmée M; van der Fels-Klerx, H J; van Asselt, Esther D; Kleter, Gijs A

    2016-11-01

    Production of sufficient, safe and nutritious food is a global challenge faced by the actors operating in the food production chain. The performance of food-producing systems from farm to fork is directly and indirectly influenced by major changes in, for example, climate, demographics, and the economy. Many of these major trends will also drive the development of food safety risks and thus will have an effect on human health, local societies and economies. It is advocated that a holistic or system approach taking into account the influence of multiple "drivers" on food safety is followed to predict the increased likelihood of occurrence of safety incidents so as to be better prepared to prevent, mitigate and manage associated risks. The value of using a Bayesian Network (BN) modelling approach for this purpose is demonstrated in this paper using food fraud as an example. Possible links between food fraud cases retrieved from the RASFF (EU) and EMA (USA) databases and features of these cases provided by both the records themselves and additional data obtained from other sources are demonstrated. The BN model was developed from 1393 food fraud cases and 15 different data sources. With this model applied to these collected data on food fraud cases, the product categories that thus showed the highest probabilities of being fraudulent were "fish and seafood" (20.6%), "meat" (13.4%) and "fruits and vegetables" (10.4%). Features of the country of origin appeared to be important factors in identifying the possible hazards associated with a product. The model had a predictive accuracy of 91.5% for the fraud type and demonstrates how expert knowledge and data can be combined within a model to assist risk managers to better understand the factors and their interrelationships. Copyright © 2016 Elsevier Ltd. All rights reserved.

  14. Does integration matter? A holistic model for building community resilience in Pakistan.

    Science.gov (United States)

    Kanta Kafle, Shesh

    2017-01-01

    This paper analyses an integrated communitybased risk reduction model adopted by the Pakistan Red Crescent. The paper analyses the model's constructs and definitions, and provides a conceptual framework and a set of practical recommendations for building community resilience. The study uses the process of outcome-based resilience index to assess the effectiveness of the approach. The results indicate that the integrated programming approach is an effective way to build community resilience as it offers a number of tangible and longlasting benefits, including effective and efficient service delivery, local ownership, sustainability of results, and improved local resilience with respect to the shock and stress associated with disaster. The paper also outlines a set of recommendations for the effective and efficient use of the model for building community resilience in Pakistan.

  15. SPRERI experience on holistic approach to utilize all parts of Jatropha curcas fruit for energy

    Energy Technology Data Exchange (ETDEWEB)

    Singh, R.N.; Vyas, D.K.; Srivastava, N.S.L.; Narra, Madhuri [Thermochemical Conversion Division, Sardar Patel Renewable Energy Research Institute, Vallabh Vidyanagar 388 120, Gujarat (India)

    2008-08-15

    Freshly harvested Jatropha dried fruit contains about 35-40% shell and 60-65% seed (by weight). The fruits are 2.5 cm long, ovoid, black and have 2-3 halves. It has nearly 400-425 fruits per kg and 1580-1600 seed per kg weight. Weight of 100 seeds is about 63 g. Jatropha shells are available after de-shelling of the Jatropha fruit while Jatropha seed husks are available after decortications of Jatropha seed for oil extraction. Seed contains about 40-42% husk/hull and 58-60% kernels. The kernels have about 50% oil. If the oil is extracted by solvent method the oil recovery is more than 95% but in mechanical expeller the oil recovery is about 85% only. If 100 kg of seed is expelled by expeller it will give about 28-30 kg oil. While lot of emphasis is being given on use of bio-diesel, which is only about 17-18% of the dry fruit, not much attention is being given to utilize other components of fruit for energy purposes. At SPRERI holistic approach has been taken to utilize all components of the Jatropha fruit - shell for combustion, hull/husk for gasification, oil and bio-diesel for running CI engines, cake for production of biogas and spent slurry as manure and it has been found that all components of the Jatropha curcas fruit can be utilized efficiently for energy purposes. This paper gives detailed information on the use of different components of J. curcas fruit for energy purposes. (author)

  16. From computer-assisted intervention research to clinical impact: The need for a holistic approach.

    Science.gov (United States)

    Ourselin, Sébastien; Emberton, Mark; Vercauteren, Tom

    2016-10-01

    The early days of the field of medical image computing (MIC) and computer-assisted intervention (CAI), when publishing a strong self-contained methodological algorithm was enough to produce impact, are over. As a community, we now have substantial responsibility to translate our scientific progresses into improved patient care. In the field of computer-assisted interventions, the emphasis is also shifting from the mere use of well-known established imaging modalities and position trackers to the design and combination of innovative sensing, elaborate computational models and fine-grained clinical workflow analysis to create devices with unprecedented capabilities. The barriers to translating such devices in the complex and understandably heavily regulated surgical and interventional environment can seem daunting. Whether we leave the translation task mostly to our industrial partners or welcome, as researchers, an important share of it is up to us. We argue that embracing the complexity of surgical and interventional sciences is mandatory to the evolution of the field. Being able to do so requires large-scale infrastructure and a critical mass of expertise that very few research centres have. In this paper, we emphasise the need for a holistic approach to computer-assisted interventions where clinical, scientific, engineering and regulatory expertise are combined as a means of moving towards clinical impact. To ensure that the breadth of infrastructure and expertise required for translational computer-assisted intervention research does not lead to a situation where the field advances only thanks to a handful of exceptionally large research centres, we also advocate that solutions need to be designed to lower the barriers to entry. Inspired by fields such as particle physics and astronomy, we claim that centralised very large innovation centres with state of the art technology and health technology assessment capabilities backed by core support staff and open

  17. An approach for holistic energy retrofitting based on assessment of economic viability and durability of energy saving measures

    DEFF Research Database (Denmark)

    Morelli, Martin

    2014-01-01

    saving measures and forget to consider, whether it is more prudent to demolished the building and erect a new building. An evaluation approach is presented to assess whether to retrofit an existing building or to demolish and replace it. The primary concept of the method is to develop a retrofitting...... as constraint to determine the amount of building retrofitting for implementation. The approach includes also durability assessments of the energy saving measures. An example is carried out to illustrate the application of the approach. The example highlights the importance of including risk assessment...... and durability evaluation of the energy saving measures when performing holistic energy retrofitting of buildings....

  18. [Establishing the idea of holistic integrative medicine, optimizing the quality of health care service in prevention and treatment].

    Science.gov (United States)

    Sun, Xing-guo

    2015-07-01

    Under background of reductionism in the modern science, physiology and medicine are stepwise refined into system, organ, disease, cell and gene etc. Although clinical medicine, only service in whole human object, obviously brought tremendous progress, it also appeared obvious defects and limits at the same time. Professionalized and specialized medicine not only needs to be integrated from basics to clinical fields, but also from prevention, health management, clinical treatment and functional rehabilitation medicine. People are indivisible organic whole. Professionalization, translation and integration must be combined. In order to provide the best quality and optimized medical service for the Chinese people and to lead in the world, we have to strengthen professional and technical knowledge, and have to establish the holistic integrative medical philosophy for physiology and medicine too.

  19. Assessing a Holistic Trait and Factor Approach to Career Development of College Students.

    Science.gov (United States)

    Johnson, Patrick; Nichols, Cassandra N.; Buboltz, Walter C., Jr.; Riedesel, Brian

    2002-01-01

    To assess the impact of a holistic career and life planning course on college students, the authors asked 209 students in treatment and control groups to complete measures of career development. Results indicate that the course significantly increases vocational identity and career decision-making self-efficacy and decreases career indecision.…

  20. Design for availability : a holistic approach to create value for manufacturers and customers of capital goods

    NARCIS (Netherlands)

    Smets, L.P.M.; Houtum, van G.J.J.A.N.; Langerak, F.

    2012-01-01

    This research introduces a holistic framework called Design for Availability that uses the principles of Lean Sigma and Design for X to cost-effectively optimize the availability of capital goods (i.e., technical systems used in the production of end-products or -services such as medical systems,

  1. CAKES (Cultural Awareness and Knowledge Exchange Scheme): A Holistic and Inclusive Approach to Supporting International Students

    Science.gov (United States)

    McKay, Jane; O'Neill, Deborah; Petrakieva, Lina

    2018-01-01

    Transition support for international students has traditionally adopted deficit models which attempt to "fix" assumed academic literacy problems. This study explores a more culturally inclusive initiative which supported international students at a UK university in a holistic and developmental way. The initiative was delivered across an…

  2. A holistic approach for perfusion assessment in septic shock: Basic foundations and clinical applications

    NARCIS (Netherlands)

    Hernández Poblete, G.W.

    2013-01-01

    A fundamental challenge in septic shock resuscitation is to evaluate tissue perfusion. In this thesis, we review the basic foundations for the development of a comprehensive and holistic model for perfusion assessment in septic shock, and outline its application to evaluate the impact of

  3. A Holistic Theoretical Approach to Intellectual Disability: Going beyond the Four Current Perspectives

    Science.gov (United States)

    Schalock, Robert L.; Luckasson, Ruth; Tassé, Marc J.; Verdugo, Miguel Angel

    2018-01-01

    This article describes a holistic theoretical framework that can be used to explain intellectual disability (ID) and organize relevant information into a usable roadmap to guide understanding and application. Developing the framework involved analyzing the four current perspectives on ID and synthesizing this information into a holistic…

  4. [Internal medicine and the holistic approach to the patient between globalization and advanced technologies].

    Science.gov (United States)

    Dammacco, Franco

    2012-06-01

    Although Internal Medicine (IM) has played for many years a crucial role in the medical education and in the diagnostic framing of the most common diseases, starting from the beginning of the 70's the knowledge explosion, the recognition of the multidisciplinary nature of IM and the consequent impossibility for the Internist to master an ever growing array of notions have resulted in the development of specialized disciplines restricted to pathologies of single organs or apparatus. The parcelling out of medical knowledge has thus induced the onset of a number of specializations stemmed from IM and, as a direct consequence, an identity crisis of the same IM. Social transformations and variations in the epidemiology of several diseases have contributed to such crisis, including aging, frailty and disability, polypathology and chronicity. In the last few years, however, IM has regained a central role in medicine, in that the Internist is an expert of "medicine of complexity" and the only specialist able to envisage an holistic approach to the patient. The development of biotechnologies, characterized on one side by nanotechnologies and on the other by the instruments of diagnostic imaging, has provided an important contribution to make clinical medicine more and more precise and reliable. The genomic analysis of novel pharmacological targets has opened new therapeutic horizons, especially in the oncology field. A striking aspect of modern medicine, again based on unreasonable expectations of improvement and recovery, is the progressive increment of malpractice claims leading to an indemnity payment. Defensive medicine has been the answer to face this growing problem: physicians are in fact induced to prescribe a much higher number of often unnecessary examinations and laboratory tests, that result in a wasting rise of health costs. In view of the rapidly changing reality, it seems fair to ask the question as to whether in our country the medical education is abreast

  5. Assessing the whole person: case managers take a holistic approach to physical and mental health.

    Science.gov (United States)

    Carter, Jolynne Jo; Zawalski, Sandra; Sminkey, Patrice V; Christopherson, Bruce

    2015-01-01

    Given the prevalence of mental health issues, particularly depressive disorders, in the U.S. population, professional case managers should increase their sensitivity to and awareness of mental illnesses, as well as their impact on physical health. Throughout the case management process, case managers frequently observe behaviors and symptoms such as those associated with depressive disorders. Case managers need to have, at a minimum, a working knowledge of mental and behavioral health issues and be familiar with basic screening tools. This will enable them to become more attuned to symptoms and behaviors that indicate that the individual should be further assessed and diagnosed by a physician. Across the case management spectrum, including acute care, accountable care organizations, patient-centered medical homes, physician practices, clinics, occupational health clinics, workers' compensation, and other settings in which case managers work with individuals (clients who receive case management services) and their families/support systems. With more than one quarter of the U.S. population affected by a depressive disorder, professional case managers who practice holistically bring together the mental and physical aspects of health. This is particularly important in a health care system and among payer sources that continue to divide the two. Case managers elevate their practice by demonstrating a greater understanding of the interconnectedness of mental and physical health and can positively influence the transdisciplinary care team to take a person-centered approach to address all health issues, in pursuit of the individual's health goals. Professional case managers must increase their understanding of mental health, becoming more aware of "red flags" that may necessitate a further evaluation and assessment by a mental health professional. They should also hone their communication skills, particularly the use of motivational interviewing techniques, to encourage

  6. Sustainability of ruminant agriculture in the new context: feeding strategies and features of animal adaptability into the necessary holistic approach.

    Science.gov (United States)

    Bocquier, F; González-García, E

    2010-07-01

    There are numerous recent studies highlighting sustainability problems for the development of ruminant production systems (RPS) while facing increasing human food necessities and global climate change. Despite the complexity of the context, in our view the main objectives of the ruminants' physiologist should be convergent for both industrialized (IC) and developing countries (DC) in a common and global strategy of advancing knowledge. In DC, this means improving the efficiency of RPS, taking into account the unique possibility of using rangelands. For IC settings, RPS should be revisited in terms of autonomy and environment- friendly feeding and managing practices. Assuming that competition for feed/food use is still a crucial criterion, future ruminant feeding systems (FeSyst) should preferably focus on lignocellulosic sources. According to biome distributions, and the recent increases in volumes of crop residues and their by-products, the annually renewed volumes of these biomasses are considerable. Therefore, we need to redesign our strategies for their efficient utilization at the local level. For this purpose, digestion processes and rumen functioning need to be better understood. The renewed vision of ruminal digestion through the reduction of greenhouse gas emissions is also a key aspect as it is an environmental demand that cannot be ignored. With regard to other ruminants' physiological functions, accumulated knowledge could be mobilized into an integrative approach that puts forward the adaptive capacities of animals to face variability in quantity and quality of supplied feeds. Basically, the reduction of inputs that were traditionally used to ensure FeSyst will need more flexible animals. In that sense, the concepts of homeostasis and teleophorhesis need to be updated and adapted to domestic species and breeds that were until now largely excluded from the dominant productive systems. In conclusion, a more holistic approach of research targets is

  7. Pheno-phenotypes: a holistic approach to the psychopathology of schizophrenia.

    Science.gov (United States)

    Stanghellini, Giovanni; Rossi, Rodolfo

    2014-05-01

    Mental disorders are mainly characterized via symptom assessment. Symptoms are state-like macroscopic anomalies of behaviour, experience, and expression that are deemed relevant for diagnostic purposes. An alternative approach is based on the concept of endophenotypes, which are physiological or behavioural measures occupying the terrain between symptoms and risk genotypes. We will critically discuss these two approaches, and later focus on the concept of pheno-phenotype as it is revealed by recent phenomenological research on schizophrenia. Several studies have been recently published on the schizophrenic pheno-phenotype mainly addressing self-disorders, as well as disorders of time and bodily experience. The mainstream approach to psychopathological phenotypes is focussed on easy-to-assess operationalizable symptoms. Thinness of phenotypes and simplification of clinical constructs are the consequences of this. Also, this approach has not been successful in investigating the biological causes of mental disorders. An integrative approach is based on the concept of 'endophenotype'. Endophenotypes were conceptualized as a supportive tool for the genetic dissection of psychiatric disorders. The underlying rationale states that disease-specific phenotypes should be the upstream phenotypic manifestation of a smaller genotype than the whole disease-related genotype. Psychopathological phenotypes can also be characterized in terms of pheno-phenotypes. This approach aims at delineating the manifold phenomena experienced by patients in all of their concrete and distinctive features, so that the features of a pathological condition emerge, while preserving their peculiar feel, meaning, and value for the patient. Systematic explorations of anomalies in the patients' experience, for example, of time, space, body, self, and otherness, may provide a useful integration to the symptom-based and endophenotype-based approaches. These abnormal phenomena can be used as pointers to the

  8. Working the way up in neurological rehabilitation: the holistic approach of nursing care.

    Science.gov (United States)

    Portillo, Mari Carmen; Cowley, Sarah

    2011-06-01

    To provide understanding of the nurses' role in neurological holistic rehabilitation and identify strategies for the enhancement of rehabilitation services. Although acute and chronic neurological patients and relatives experience emotional and social changes, most rehabilitation programmes do not deal with non-physical needs or involve nurses, leading to a poor definition and specialisation of the nursing role. Action research. The project took place in two neurological wards of a highly specialised hospital in Spain and lasted 30 months. An individualised nurse-led social rehabilitation programme was planned, implemented and evaluated. The nursing role and care in rehabilitation were explored with 37 nurses and 40 neurological patients and 40 relatives (convenience sampling). Semi-structured interviews and participant observations were developed. Content (QSR NUDIST Vivo v.2.0) and statistical (SPSS v. 13.0) analyses were run. The lack of time, knowledge and experience, the poor definition of the nursing role and ineffective communication with users limited holistic care in the wards. Some enhancing nursing strategies were proposed and explored: promotion of acceptance/adaptation of the disease through education, reinforcement of the discharge planning and planning of emotional and social choices based on the assessment of individual needs and resources at home. Nursing professionals are in a privileged position to deal with neurological patients' and carers' holistic needs. Several attributes of the advanced nursing role in rehabilitation teams have been proposed to deal with non-physical aspects of care. • Rehabilitation needs of neurological patients and carers at hospital have been described. • Nurses' perceptions of their work and role in rehabilitation have been presented. • Clinical strategies to develop the advanced nursing role in holistic neurological rehabilitation have been highlighted. © 2010 Blackwell Publishing Ltd.

  9. Specifying process requirements for holistic care.

    Science.gov (United States)

    Poulymenopoulou, M; Malamateniou, F; Vassilacopoulos, G

    2013-09-01

    Holistic (health and social) care aims at providing comprehensive care to the community, especially to elderly people and people with multiple illnesses. In turn, this requires using health and social care resources more efficiently through enhanced collaboration and coordination among the corresponding organizations and delivering care closer to patient needs and preferences. This paper takes a patient-centered, process view of holistic care delivery and focuses on requirements elicitation for supporting holistic care processes and enabling authorized users to access integrated patient information at the point of care when needed. To this end, an approach to holistic care process-support requirements elicitation is presented which is based on business process modeling and places particular emphasis on empowering collaboration, coordination and information sharing among health and social care organizations by actively involving users and by providing insights for alternative process designs. The approach provides a means for integrating diverse legacy applications in a process-oriented environment using a service-oriented architecture as an appropriate solution for supporting and automating holistic care processes. The approach is applied in the context of emergency medical care aiming at streamlining and providing support technology to cross-organizational health and social care processes to address global patient needs.

  10. A holistic approach to control process safety risks: Possible ways forward

    International Nuclear Information System (INIS)

    Pasman, H.J.; Knegtering, B.; Rogers, W.J.

    2013-01-01

    Pursuing process safety in a world of continuously increasing requirements is not a simple matter. Keeping balance between producing quality and volume under budget constraints while maintaining an adequate safety level proves time and time again a difficult task given that evidently major accidents cannot be avoided. Lack of resilience from an organizational point of view to absorb unwanted and unforeseen disturbances has in recent years been put forward as a major cause, while organizational erosive drift is shown to be responsible for complacency and degradation of safety attitude. A systems approach to safety provides a new paradigm with the promise of new comprehensive tools. At the same time, one realizes that risk assessment will fall short of identifying and quantifying all possible scenarios. First, human error is in most assessments not included. It is even argued that determining human failure probability by decomposing it to basic elements of error is not possible. Second, the crux of the systemic approach is that safety is an emergent property, which means the same holds for the technological aspect: risk is not fully predictable from failure of components. By surveying and applying recent literature, besides analysing, this paper proposes a way forward by considering resilience of a socio-technical system both from an organizational and a technical side. The latter will for a large part be determined by the plant design. Sufficient redundancy and reserve shall be kept to preserve sufficient resilience, but the question that rises is how. Available methods are risk assessment and process simulation. It is helpful that the relation between risk and resilience analysis has been recently defined. Also, in a preliminary study the elements of resilience of a process have become listed. In the latter, receiving and interpreting weak signals to boost situational awareness plays an important role. To maintain alertness on the functioning of a safety management

  11. Holistic Nursing Simulation: A Concept Analysis.

    Science.gov (United States)

    Cohen, Bonni S; Boni, Rebecca

    2018-03-01

    Simulation as a technology and holistic nursing care as a philosophy are two components within nursing programs that have merged during the process of knowledge and skill acquisition in the care of the patients as whole beings. Simulation provides opportunities to apply knowledge and skill through the use of simulators, standardized patients, and virtual settings. Concerns with simulation have been raised regarding the integration of the nursing process and recognizing the totality of the human being. Though simulation is useful as a technology, the nursing profession places importance on patient care, drawing on knowledge, theories, and expertise to administer patient care. There is a need to promptly and comprehensively define the concept of holistic nursing simulation to provide consistency and a basis for quality application within nursing curricula. This concept analysis uses Walker and Avant's approach to define holistic nursing simulation by defining antecedents, consequences, and empirical referents. The concept of holism and the practice of holistic nursing incorporated into simulation require an analysis of the concept of holistic nursing simulation by developing a language and model to provide direction for educators in design and development of holistic nursing simulation.

  12. Towards a more holistic research approach to plant conservation: the case of rare plants on oceanic islands.

    Science.gov (United States)

    Silva, Luís; Dias, Elisabete Furtado; Sardos, Julie; Azevedo, Eduardo Brito; Schaefer, Hanno; Moura, Mónica

    2015-06-11

    Research dedicated to rare endemic plants is usually focused on one given aspect. However, holistic studies, addressing several key issues, might be more useful, supporting management programmes while unravelling basic knowledge about ecological and population-level processes. A more comprehensive approach to research is proposed, encompassing: phylogenetics/systematics, pollination biology and seed dispersal, propagation, population genetics, species distribution models (SDMs), threats and monitoring. We present a holistic study dedicated to Veronica dabneyi Hochst. ex Seub., an endangered chamaephyte endemic to the Azores. Veronica dabneyi was mainly found associated with other endemic taxa; however, invasive plants were also present and together with introduced cattle, goats and rabbits are a major threat. Most populations grow at somewhat rocky and steep locations that appeared to work as refuges. Seed set in the wild was generally high and recruitment of young plants from seed seemed to be frequent. In the laboratory, it was possible to germinate and fully develop V. dabneyi seedlings, which were planted at their site of origin. No dormancy was detected and time for 50 % germination was affected by incubation temperature. Eight new microsatellite markers were applied to 72 individuals from 7 sites. A considerable degree of admixture was found between samples from the two islands Flores and Corvo, with 98 % of the genetic variability allocated within populations. Levels of heterozygosity were high and no evidence of inbreeding was found. Species distribution models based on climatic and topographic variables allowed the estimation of the potential distribution of V. dabneyi on Flores and Corvo using ecological niche factor analysis and Maxent. The inclusion of land-use variables only slightly increased the information explained by the models. Projection of the expected habitat in Faial largely coincided with the only historic record of V. dabneyi on that island

  13. Reductionist versus holistic approaches to the study of river meandering: An ideal dialogue

    Science.gov (United States)

    Seminara, G.; Pittaluga, M. Bolla

    2012-08-01

    We discuss some recent attempts to apply the theory of nonlinear dynamical systems to the interpretation of the long term morphodynamic evolution of meandering rivers. To make the discussion attractive for the reader, we employ the method of a Socratic dialogue between a member of the so called 'reductionist community', who is inclined to support only theories based on physical principles and who is skeptical about fashionable new paradigms, and a member of the 'holistic community', who supports the idea that new paradigms are needed because rivers are complex systems, whose response can only be interpreted using tools that analyze the system "as a whole". The dialogue focuses on a selection of recent contributions which assesses the progress in understanding of meander dynamics achieved by the use of the above new paradigms. The discussion suggests that some consensus has been reached on the fractal nature of meandering patterns, with the fractal dimension playing the role of a morphometric parameter. On the contrary, despite different early suggestions, recent thorough analysis has been unable to detect any clear evidence that the evolution of meanders displays the characters of either a chaotic or a self organized critical process. The dialogue is concluded with some consensus on the perspective that well founded cellular models may possibly help reconciling the reductionist and holistic viewpoints.

  14. A Review and Integrative Analysis of Ancient Holistic Character Medicine Systems

    Directory of Open Access Journals (Sweden)

    Søren Ventegodt

    2007-01-01

    Full Text Available The ancient holistic medical systems help the patient by balancing the “elements” of the human character. This work aims to understand the nature of these elements and the process of the physician balancing them. Using the concept of poly-ray cosmology we see that the medical systems from ancient India, China and Greek basically share the same inner structure and also the same logic of the treatment processes. We analyze the double concept of yin-yang, the Ayurvedic triadic concepts of Pitta, Kapha and Vata, the four elements of Hippocratic humoral medicine, and the five elements of Chinese medicine, and find that each of these conceptual frameworks make up a “theory” or model of the world that is a perfect wholeness, allowing the physician to interpret the world and his patient in order to identify the imbalances of his or her character that need to be treated. Independently of the system this can be a palliative treatment, if energies are only balanced in present time, or a causal cure if the physician is using the similarity principle to take his patient into regression back to the events in the personal history that originally created the imbalances (the traumas. To help the patient back to the traumas he is exposed to a small dose of the original harming stimulus; this can be an internal process like visualization supported by the therapist words, or an external process provoked by his actions. If the physician is balancing the elements without such a healing of the patient's existential core this can still momentarily help the patient by alleviating the symptoms, but it will not have a permanent effect.

  15. 2. Gestaltdrama as an Integrative Psychotherapeutic Approach

    Directory of Open Access Journals (Sweden)

    Polínek Martin Dominik

    2016-03-01

    Full Text Available The following text is an overview study which defines the basic phenomena and effective factors of Gestalt drama and outlines some of the researches carried out in this area by the author during recent years. Gestalt drama is the name of a specific psychotherapeutic approach applied by the author in his practice, which combines Gestalt therapy with expressive approaches (especially with dramatherapy, theatrotherapy and fairytale-therapy. Linking Gestalt therapy and expressive techniques results in a specific psychotherapeutic approach whose versatility and holistic conception makes it suitable not only for psychotherapy but also for self-development of people with special needs, as it has the potential to meet the higher psychological needs even when the lower needs are not sufficiently saturated. The article further presents the interpretation of the partial results of research focusing on the analysis of integration performance where gestaltdrama techniques have been applied. These performances resulted from one-day dramatherapy workshops with clients suffering from mental retardation and with clients with behavioural disorders. This includes the analysis of differences between dramatical expression within the above target groups.

  16. An holistic approach to the problem of reactor ageing. [Pressure vessel embrittlement

    Energy Technology Data Exchange (ETDEWEB)

    Phythian, W.; McElroy, R.; Druce, S.; Kovan, D. (AEA Reactor Services, Harwell (United Kingdom))

    1992-12-01

    Understanding the process of ageing in reactors is essential to extending their lives beyond original design. To present a sound case -particularly regarding the level of embrittlement in reactor vessels due to radiation damage - an integrated approach using advanced assessment tools is needed. The techniques developed for the purpose involve, on the microscopic level, advanced neutron dosimetry and high resolution measurement techniques (eg advanced electron beam techniques and small angle neutron scattering) with which an analysis can be done of the radiation damage and the microstructural state of the steel test procedures (tensile, fracture toughness and Charpy impact) on standard and sub-sized specimens, the extent of radiation degradation can be characterised. finally, it is possible to predict how the degradation will evolve using physically-based models of embrittlement. (Author).

  17. Approach to the holistic analysis of the system man--energy--environment

    Energy Technology Data Exchange (ETDEWEB)

    Voss, A

    1973-07-01

    Thesis. Energy is generally considered as the main access to the modern industrial society. The availability of sufficient amounts of energy as due to fundamental importance for the development of society. Besides the demand on economical energy maintenance, there are intensively occurring ecological and supply-technical aspects. whose importance advances permanently with the exponential increase of the energy consumption. A holistic analysis for the system man--enengy -environment regarding economical, ecological, and technical aspects is presented. The aim is to comprehend all significant influence factors and interactions as well as to compare and to evaluate the positive and negative effects of an increasing enengy consumption and its protection by alternative energy supply systems. For such complex systems new methods developed in the field of system engineering, especially cybernetic simulation, have to be used for the derivation of adequate aid for decision. (auth)

  18. Aging in Community: Developing a More Holistic Approach to Enhance Older Adults' Well-Being.

    Science.gov (United States)

    Davitt, Joan K; Madigan, Elizabeth A; Rantz, Marilyn; Skemp, Lisa

    2016-01-01

    Public health advances have contributed to increased longevity; however, individuals are more likely to live longer with multiple chronic conditions. The existing health care system primarily focuses on treating disease rather than addressing well-being as a holistic construct that includes physical, social, and environmental components. The current commentary emphasizes the importance of supporting healthy active aging and aging in community. The barriers to aging in community and the state of the intervention science in response to this problem are discussed, and recommendations for future research are provided. Active aging is more than managing illness or care transitions-it promotes engagement, participation, dignity, self-fulfillment, self-determination, and support for older adults. To support aging in community and healthy active aging, a paradigm shift is needed in how the well-being of older adults is thought about and supported. Copyright 2016, SLACK Incorporated.

  19. National, holistic, watershed-scale approach to understand the sources, transport, and fate of agricultural chemicals

    Science.gov (United States)

    Capel, P.D.; McCarthy, K.A.; Barbash, J.E.

    2008-01-01

    This paper is an introduction to the following series of papers that report on in-depth investigations that have been conducted at five agricultural study areas across the United States in order to gain insights into how environmental processes and agricultural practices interact to determine the transport and fate of agricultural chemicals in the environment. These are the first study areas in an ongoing national study. The study areas were selected, based on the combination of cropping patterns and hydrologic setting, as representative of nationally important agricultural settings to form a basis for extrapolation to unstudied areas. The holistic, watershed-scale study design that involves multiple environmental compartments and that employs both field observations and simulation modeling is presented. This paper introduces the overall study design and presents an overview of the hydrology of the five study areas. Copyright ?? 2008 by the American Society of Agronomy, Crop Science Society of America, and Soil Science Society of America. All rights reserved.

  20. Improving allergy management in the primary care network--a holistic approach.

    Science.gov (United States)

    Jutel, M; Angier, L; Palkonen, S; Ryan, D; Sheikh, A; Smith, H; Valovirta, E; Yusuf, O; van Wijk, R G; Agache, I

    2013-11-01

    The incidence, prevalence and costs of allergy have increased substantially in recent decades in many parts of Europe. The dominant model of allergy care within Europe is at the moment specialist-based. This model will become unsustainable and undeliverable with increasing disease prevalence. One solution to increase provision of allergy services is to diversify the providers. A new model for the provision of allergy care in the community with the general practitioner at the forefront is proposed. Pre- and postgraduate allergy education and training, implementation of pathways of care, allergy specialization and political will to generate resources and support are essential to achieve this new model. In parallel the holistic view of allergic diseases should be maintained, including assessment of severity and risk, psychological factors and health-care related costs in the context of the patient-centered decision making process. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  1. Integrating Product Water Quality Effects In Holistic Assessments Of Water Systems

    OpenAIRE

    Rygaard, Martin

    2011-01-01

    While integrated assessments of sustainability of water systems are largely focused on quantity issues, chemical use, and energy consumption, effects of the supplied water quality are often overlooked. Drinking water quality affects corrosion rates, human health, applicability of water and aesthetics. Even small changes in the chemical composition of water may accumulate large impacts on city scale. Here, a method for integrated assessment of water quality is presented. Based on dose-response...

  2. Preserved appreciation of aesthetic elements of speech and music prosody in an amusic individual: A holistic approach.

    Science.gov (United States)

    Loutrari, Ariadne; Lorch, Marjorie Perlman

    2017-07-01

    We present a follow-up study on the case of a Greek amusic adult, B.Z., whose impaired performance on scale, contour, interval, and meter was reported by Paraskevopoulos, Tsapkini, and Peretz in 2010, employing a culturally-tailored version of the Montreal Battery of Evaluation of Amusia. In the present study, we administered a novel set of perceptual judgement tasks designed to investigate the ability to appreciate holistic prosodic aspects of 'expressiveness' and emotion in phrase length music and speech stimuli. Our results show that, although diagnosed as a congenital amusic, B.Z. scored as well as healthy controls (N=24) on judging 'expressiveness' and emotional prosody in both speech and music stimuli. These findings suggest that the ability to make perceptual judgements about such prosodic qualities may be preserved in individuals who demonstrate difficulties perceiving basic musical features such as melody or rhythm. B.Z.'s case yields new insights into amusia and the processing of speech and music prosody through a holistic approach. The employment of novel stimuli with relatively fewer non-naturalistic manipulations, as developed for this study, may be a useful tool for revealing unexplored aspects of music and speech cognition and offer the possibility to further the investigation of the perception of acoustic streams in more authentic auditory conditions. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  3. Evolution of a holistic systems approach to planning and managing road safety: the Victorian case study, 1970-2015.

    Science.gov (United States)

    Muir, Carlyn; Johnston, Ian R; Howard, Eric

    2018-06-01

    The Victorian Safe System approach to road safety slowly evolved from a combination of the Swedish Vision Zero philosophy and the Sustainable Safety model developed by the Dutch. The Safe System approach reframes the way in which road safety is viewed and managed. This paper presents a case study of the institutional change required to underpin the transformation to a holistic approach to planning and managing road safety in Victoria, Australia. The adoption and implementation of a Safe System approach require strong institutional leadership and close cooperation among all the key agencies involved, and Victoria was fortunate in that it had a long history of strong interagency mechanisms in place. However, the challenges in the implementation of the Safe System strategy in Victoria are generally neither technical nor scientific; they are predominantly social and political. While many governments purport to develop strategies based on Safe System thinking, on-the-ground action still very much depends on what politicians perceive to be publicly acceptable, and Victoria is no exception. This is a case study of the complexity of institutional change and is presented in the hope that the lessons may prove useful for others seeking to adopt more holistic planning and management of road safety. There is still much work to be done in Victoria, but the institutional cultural shift has taken root. Ongoing efforts must be continued to achieve alert and compliant road users; however, major underpinning benefits will be achieved through focusing on road network safety improvements (achieving forgiving infrastructure, such as wire rope barriers) in conjunction with reviews of posted speed limits (to be set in response to the level of protection offered by the road infrastructure) and by the progressive introduction into the fleet of modern vehicle safety features. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights

  4. Successful engagement: CBM's holistic approach to the work in the area of ear care, deafness, hard of hearing and deafblindness.

    Science.gov (United States)

    Tesni, Sian; Santana-Hernández, Diego

    2014-09-01

    CBM is an international Christian development organisation, committed to improving the quality of life of persons with disabilities in disadvantaged societies. CBM aims at achieving this in partnership with local organisations and in cooperation with stakeholders at regional and international levels. This article aims at sharing CBM's holistic approach for successful engagement in the work area of ear care, deafness, hard of hearing and deafblindness. Review of CBM supporting documents, including strategies, position papers, technical guidelines, criteria of success and information related to partners, centres of excellence and model projects. Description of how partner programmes use participatory methods of planning and implementation, involving persons with disabilities and the community. Recommendations on how to develop national or sub-national strategies to impact the lives, and advocate with governments for the rights and inclusion, of persons with disabilities. CBM's holistic approach to work in the area of ear care; deafness; hard of hearing and deafblindness includes intervention at all levels of health care provision, Education, CBR and Audiological, Speech Therapy and other interdisciplinary services. This article presents CBM's core principles and shares specific strategic planning and results, together with lessons learnt while searching a sustainable engagement for field work. Rehabilitation, in its widest conception, should be approached as a multidisciplinary strategy, and developed in close cooperation with other local, national and international agencies. CBM is positioned in a strategic point from where it can play a key role in the facilitation of an international forum for agencies and stakeholders to reach a consensus to decrease the burden of ear disease and hearing loss, through early intervention and re/habilitation.

  5. A holistic approach to the management of Erb′s palsy

    Directory of Open Access Journals (Sweden)

    Dasari Srilakshmi

    2013-01-01

    Full Text Available A 4.5-month-old female baby, presenting with complete paralysis of right upper limb with typical waiter′s tip deformity, diagnosed as Erb′s palsy was brought to Sri Ganapati Sachchidananda Hospital. Patient was treated with an integrated approach of physiotherapy and Ayurvedic treatment with an intention of aiding faster recovery of the patient to lead a near normal life. As per Ayurvedic classics, this condition can be correlated to Ekangavata (Vata effecting any one part of the body, which is Apatarpana in nature (diseases with deprived growth of body tissue. Hence, the choice of treatment is Santarpana Chikitsa (nourishing treatment. Santarpana Bahyopakramas (nourishing external treatment modalities such as Ashwagandhabalalakshadi Taila (Ayurvedic medicated oil Abhyanga (oleation therapy and Shastikashali Anna Lepa (application of processed rice paste were administered along with electrical stimulation (physiotherapy modality, both galvanic and faradic current in three sessions. Appreciable results were observed in the form of reduction of disparity in length and mid-arm circumference of right upper limb compared to unaffected left upper limb and the muscle power too improved from zero to four, facilitating patient to near normal movement.

  6. Humanization in healthcare arises from the need for a holistic approach to illness.

    Science.gov (United States)

    de la Fuente-Martos, C; Rojas-Amezcua, M; Gómez-Espejo, M R; Lara-Aguayo, P; Morán-Fernandez, E; Aguilar-Alonso, E

    2018-03-01

    Suffering is not only exclusive to patients or their relatives, but also to the health professionals, who feel to be at the center of the depersonalization process. Over-technification and the fact that the disease process is sometimes the only focal point of our activities, together with the ever-increasing influence of institutional power seen in recent times, all cause the health professional to be the first in demanding a change in health institution dynamics. Following initial reflection from one of the most technified medical specialties (Intensive Care Medicine), classically isolated from the rest of the Hospital and from the community, we implemented a project aimed at securing integration and empathy in our approach to patients and their relatives in the Intensive Care Unit (ICU) of Infanta Margarita Hospital. The project was designed to incorporate tools for working on the most important elements of a humanization plan, i.e., the patients, their relatives, the health professionals and the community, attempting to disclose the work done in the ICU over a period of 12 months. This project is referred to as the Project ICU Infanta Margarita: 1 year: 12 months for 12 commitments. Copyright © 2017 Elsevier España, S.L.U. y SEMNIM. All rights reserved.

  7. The three domains of value: Why IL practitioners must take a holistic approach

    Directory of Open Access Journals (Sweden)

    Andrew Whitworth

    2010-09-01

    Full Text Available Many definitions of IL focus on the subjective value of information - the learner expected to be the initiator, agent and evaluator of an information search. However, we must also judge information against the objective domain: without it, we risk what Damian Thompson has called ‘counterknowledge’, the spread of unscientific worldviews like conspiracy theories, pseudohistory and so on. There is also the intersubjective domain, the field of laws, morals, economics and community standards. Without this domain we may collapse into relativism. But the subjective domain remains valuable, as otherwise we would suffer from ‘groupthink’, becoming merely the instrument of organisations and ‘the system’. All three domains of value are thus essential if the informational resources on which we draw are to be sustainable, healthy and open, and if we are to respond to the challenges posed by diversity and highlighted by this conference. Why, then, is so little IL teaching thinking about its subject in this way? I suggest the answers lie in how governments and other influential educational stakeholders conceive of their ‘product’. Not every educational stakeholder wants to see the kind of critical, creative thinkers which holistic IL is oriented to producing. Addressing this paradox is a significant policy challenge facing IL as it matures in the 21st century.

  8. No Simple Answers: A Holistic Approach to Issues Concerning Obesity and African Dance

    Directory of Open Access Journals (Sweden)

    Maxwell Xolani Rani

    2017-02-01

    Full Text Available Obesity is a growing health issue in South Africa that carries health risk detrimental to those living in Black townships. The author will argue that the use of South African traditional urban dances may be permissible option for replacing aerobics to help prevent and combat obesity. Christian missionaries, colonizers, Western education, urbanization, and apartheid have had negative impacts on South African traditional rural dances; however, South Africans who migrated to urban environments in the nineteenth and twentieth centuries transformed traditions under spatial and ideological constraints and created new South African traditional urban social dances. South African traditional urban social dances were created in urban environments, in slum yards and townships, and do not reach the same level of sacred ritual that South African traditional rural social dances do; thus, their use in Black townships to help fight obesity is a possibility that must be further researched. The use of South African traditional urban social dances may not only help prevent and reduce obesity, but also help build community, teach history, facilitate self-exploration in a holistic manner, and open doors for the youth of today to continue to transform traditional urban social dances to reflect the current realities they are experiencing in Black townships.

  9. Integrating Cost as an Independent Variable Analysis with Evolutionary Acquisition - A Multiattribute Design Evaluation Approach

    Science.gov (United States)

    2003-03-01

    within the Automated Cost Estimating Integrated Tools ( ACEIT ) software suite (version 5.x). With this capability, one can set cost targets or time...not allow the user to vary more than one decision variable. This limitation of the ACEIT approach thus hinders a holistic view when attempting to

  10. A holistic approach for food waste management towards zero-solid disposal and energy/resource recovery.

    Science.gov (United States)

    Ma, Yingqun; Yin, Yao; Liu, Yu

    2017-03-01

    This study developed a holistic approach which was based on the ultra-fast hydrolysis of food waste with the fungal mash rich in various hydrolytic enzymes produced in situ from food waste as well. After the 8-h hydrolytic treatment, the solid residue and liquor were separated. It was found that the produced solid residue can meet all the requirements for biofertilizer in terms of NPK and heavy metal contents, while the separated liquor with high soluble organics concentration was further subject to anaerobic digestion for enhanced biomethane production. The results showed that 0.41kg of biofertilizer with a moisture content of 76.9% and 54.4L of biomethane could be produced from 1kg of food waste. As such, it is expected that this study may lead to the paradigm shift in food waste management with the ultimate target of zero-solid discharge. Copyright © 2016 Elsevier Ltd. All rights reserved.

  11. A holistic method to assess building energy efficiency combining D-S theory and the evidential reasoning approach

    International Nuclear Information System (INIS)

    Yao Runming; Yang Yulan; Li Baizhan

    2012-01-01

    The assessment of building energy efficiency is one of the most effective measures for reducing building energy consumption. This paper proposes a holistic method (HMEEB) for assessing and certifying energy efficiency of buildings based on the D-S (Dempster-Shafer) theory of evidence and the Evidential Reasoning (ER) approach. HMEEB has three main features: (i) it provides both a method to assess and certify building energy efficiency, and exists as an analytical tool to identify improvement opportunities; (ii) it combines a wealth of information on building energy efficiency assessment, including identification of indicators and a weighting mechanism; and (iii) it provides a method to identify and deal with inherent uncertainties within the assessment procedure. This paper demonstrates the robustness, flexibility and effectiveness of the proposed method, using two examples to assess the energy efficiency of two residential buildings, both located in the ‘Hot Summer and Cold Winter’ zone in China. The proposed certification method provides detailed recommendations for policymakers in the context of carbon emission reduction targets and promoting energy efficiency in the built environment. The method is transferable to other countries and regions, using an indicator weighting system to modify local climatic, economic and social factors. - Highlights: ► Assessing energy efficiency of buildings holistically; ► Applying the D-S (Dempster-Shafer) theory of evidence and the Evidential Reasoning (ER) approach; ► Involving large information and uncertainties in the energy efficiency decision-making process. ► rigorous measures for policymakers to meet carbon emission reduction targets.

  12. Natural ecosystem mimicry in traditional dryland agroecosystems: Insights from an empirical and holistic approach.

    Science.gov (United States)

    Blanco, Julien; Michon, Geneviève; Carrière, Stéphanie M

    2017-12-15

    While the aim of Ecological Intensification is to enable the design of more sustainable and productive agricultural systems, it is not suited to dryland agroecosystems that are driven by non-equilibrium dynamics and intrinsic variability. Instead, a model based on mobility and variability management has been proposed for these agroecosystems. However, this model remains under-applied in southern Morocco where there have been few studies on the functioning of traditional agroecosystems. This paper focuses on an agroecosystem in the Moroccan Saharan fringe zone that combines agriculture and pastoralism in an acacia parkland. A grounded theory approach was used over a three-year investigation period (i) to highlight how agro-pastoral activities interface with environmental variability, and (ii) to analyze the formal and informal institutions that support these activities. Results show that farmers interface with rainfall variability through (i) an opportunistic agricultural calendar, (ii) a variation of cultivated areas, and (iii) crop diversification. Herders combine macro-mobility (nomads move over long distances to track rainfall) and micro-mobility (nomadic and sedentary herds are driven on a daily basis around settlements) to optimize the exploitation of ecological heterogeneity. During droughts, they also resort to State-subsidized forage supplies. Both cultivation and pastoral activities tend to interface with ecological dynamics and to mimic nature, resulting in a human-modified parkland that could be considered as a 'green agroecosystem'. The sustainability of natural resource use relies on flexible property rights, backed up by a social and cultural norm-based regulation system, that allow crop-livestock integration and landscape collective management. Despite encouraging results, the agroecosystem appears to be threatened by current agricultural policies, rural exodus and the lack of social recognition of nomadism. Nevertheless, because ecosystem mimicry of

  13. A proposed holistic approach to on-chip, off-chip, test, and package interconnections

    Science.gov (United States)

    Bartelink, Dirk J.

    1998-11-01

    The term interconnection has traditionally implied a `robust' connection from a transistor or a group of transistors in an IC to the outside world, usually a PC board. Optimum system utilization is done from outside the IC. As an alternative, this paper addresses `unimpeded' transistor-to-transistor interconnection aimed at reaching the high circuit densities and computational capabilities of neighboring IC's. In this view, interconnections are not made to some human-centric place outside the IC world requiring robustness—except for system input and output connections. This unimpeded interconnect style is currently available only through intra-chip signal traces in `system-on-a-chip' implementations, as exemplified by embedded DRAMs. Because the traditional off-chip penalty in performance and wiring density is so large, a merging of complex process technologies is the only option today. It is suggested that, for system integration to move forward, the traditional robustness requirement inherited from conventional packaging interconnect and IC manufacturing test must be discarded. Traditional system assembly from vendor parts requires robustness under shipping, inspection and assembly. The trend toward systems on a chip signifies willingness by semiconductor companies to design and fabricate whole systems in house, so that `in-house' chip-to-chip assembly is not beyond reach. In this scenario, bare chips never leave the controlled environment of the IC fabricator while the two major contributors to off-chip signal penalty, ESD protection and the need to source a 50-ohm test head, are avoided. With in-house assembly, ESD protection can be eliminated with the precautions already familiar in plasma etching. Test interconnection impacts the fundamentals of IC manufacturing, particularly with clock speeds approaching 1GHz, and cannot be an afterthought. It should be an integral part of the chip-to-chip interconnection bandwidth optimization, because—as we must

  14. Clinical Holistic Medicine: The Case Story of Anna. I. Long-Term Effect of Childhood Sexual Abuse and Incest with a Treatment Approach

    Directory of Open Access Journals (Sweden)

    Søren Ventegodt

    2006-01-01

    Full Text Available The nervous breakdown of a 22-year-old, young woman was caused by severe sexual abuse in childhood, which was repressed over many years. During therapy, the patient accumulated resources to start the painful integration of these old traumas. Using holistic existential therapy in accordance with the life mission theory and the holistic process theory of healing, she finally was able to confront her old traumas and heal her existence. She seemingly recovered completely (including regaining full emotional range through holistic existential therapy, individually and in a group. The therapy took 18 months and more than 100 hours of intensive therapy. In the beginning of the therapy, the issues were her physical and mental health; in the middle of the therapy, the central issue was her purpose of life and her love life; and at the conclusion of the therapy, the issue was gender and sexuality. The strategy was to build up her strength for several months, mobilizing hidden resources and motivation for living, before the old traumas could be confronted and integrated. The therapy was based on quality of life philosophy, on the life mission theory, the theory of ego, the theory of talent, the theory of the evil side of man, the theory of human character, and the holistic process theory of healing. The clinical procedures included conversation, philosophical training, group therapeutic tools, extended use of therapeutic touch, holistic pelvic examination, and acceptance through touch was used to integrate the early traumas bound to the pelvis and scar tissue in the sexual organs. She was processed according to 10 levels of the advanced toolbox for holistic medicine and the general plan for clinical holistic psychiatry. The emotional steps she went through are well described by the scale of existential responsibility. The case story of Anna is an example of how even the most severely ill patient can recover fully with the support of holistic medical

  15. Clinical holistic medicine: the case story of Anna. I. Long-term effect of childhood sexual abuse and incest with a treatment approach.

    Science.gov (United States)

    Ventegodt, Søren; Clausen, Birgitte; Merrick, Joav

    2006-02-02

    The nervous breakdown of a 22-year-old, young woman was caused by severe sexual abuse in childhood, which was repressed over many years. During therapy, the patient accumulated resources to start the painful integration of these old traumas. Using holistic existential therapy in accordance with the life mission theory and the holistic process theory of healing, she finally was able to confront her old traumas and heal her existence. She seemingly recovered completely (including regaining full emotional range) through holistic existential therapy, individually and in a group. The therapy took 18 months and more than 100 hours of intensive therapy. In the beginning of the therapy, the issues were her physical and mental health; in the middle of the therapy, the central issue was her purpose of life and her love life; and at the conclusion of the therapy, the issue was gender and sexuality. The strategy was to build up her strength for several months, mobilizing hidden resources and motivation for living, before the old traumas could be confronted and integrated. The therapy was based on quality of life philosophy, on the life mission theory, the theory of ego, the theory of talent, the theory of the evil side of man, the theory of human character, and the holistic process theory of healing. The clinical procedures included conversation, philosophical training, group therapeutic tools, extended use of therapeutic touch, holistic pelvic examination, and acceptance through touch was used to integrate the early traumas bound to the pelvis and scar tissue in the sexual organs. She was processed according to 10 levels of the advanced toolbox for holistic medicine and the general plan for clinical holistic psychiatry. The emotional steps she went through are well described by the scale of existential responsibility. The case story of Anna is an example of how even the most severely ill patient can recover fully with the support of holistic medical treatment, making her feel

  16. Clinical Holistic Medicine: The Case Story of Anna. I. Long-Term Effect of Childhood Sexual Abuse and Incest with a Treatment Approach

    Science.gov (United States)

    Ventegodt, Søren; Clausen, Birgitte; Merrick, Joav

    2006-01-01

    The nervous breakdown of a 22-year-old, young woman was caused by severe sexual abuse in childhood, which was repressed over many years. During therapy, the patient accumulated resources to start the painful integration of these old traumas. Using holistic existential therapy in accordance with the life mission theory and the holistic process theory of healing, she finally was able to confront her old traumas and heal her existence. She seemingly recovered completely (including regaining full emotional range) through holistic existential therapy, individually and in a group. The therapy took 18 months and more than 100 hours of intensive therapy. In the beginning of the therapy, the issues were her physical and mental health; in the middle of the therapy, the central issue was her purpose of life and her love life; and at the conclusion of the therapy, the issue was gender and sexuality. The strategy was to build up her strength for several months, mobilizing hidden resources and motivation for living, before the old traumas could be confronted and integrated. The therapy was based on quality of life philosophy, on the life mission theory, the theory of ego, the theory of talent, the theory of the evil side of man, the theory of human character, and the holistic process theory of healing. The clinical procedures included conversation, philosophical training, group therapeutic tools, extended use of therapeutic touch, holistic pelvic examination, and acceptance through touch was used to integrate the early traumas bound to the pelvis and scar tissue in the sexual organs. She was processed according to 10 levels of the advanced toolbox for holistic medicine and the general plan for clinical holistic psychiatry. The emotional steps she went through are well described by the scale of existential responsibility. The case story of Anna is an example of how even the most severely ill patient can recover fully with the support of holistic medical treatment, making her feel

  17. Construct Validity of the Holistic Complementary and Alternative Medicines Questionnaire (HCAMQ)—An Investigation Using Modern Psychometric Approaches

    Science.gov (United States)

    Kersten, Paula; White, P. J.; Tennant, A.

    2011-01-01

    The scientific basis of efficacy studies of complementary medicine requires the availability of validated measures. The Holistic Complementary and Alternative Medicine Questionnaire (HCAMQ) is one such measure. This article aimed to examine its construct validity, using a modern psychometric approach. The HCAMQ was completed by 221 patients (mean age 66.8, SD 8.29, 58% females) with chronic stable pain predominantly from a single joint (hip or knee) of mechanical origin, waiting for a hip (40%) or knee (60%) joint replacement, on enrolment in a study investigating the effects of acupuncture and placebo controls. The HCAMQ contains a Holistic Health (HH) Subscale (five items) and a CAM subscale (six items). Validity of the subscales was tested using Cronbach alpha's, factor analysis, Mokken scaling and Rasch analysis, which did not support the original two-factor structure of the scale. A five-item HH subscale and a four-item CAM subscale (worded in a negative direction) fitted the Rasch model and were unidimensional (χ2 = 8.44, P = 0.39, PSI = 0.69 versus χ2 = 17.33, P = 0.03, PSI = 0.77). Two CAM items (worded in the positive direction) had significant misfit. In conclusion, we have shown that the original two-factor structure of the HCAMQ could not be supported but that two valid shortened subscales can be used, one for HH Beliefs (four-item HH), and the other for CAM Beliefs (four-item CAM). It is recommended that consideration is given to rewording the two discarded positively worded CAM questions to enhance construct validity. PMID:19793835

  18. Construct Validity of the Holistic Complementary and Alternative Medicines Questionnaire (HCAMQ—An Investigation Using Modern Psychometric Approaches

    Directory of Open Access Journals (Sweden)

    Paula Kersten

    2011-01-01

    Full Text Available The scientific basis of efficacy studies of complementary medicine requires the availability of validated measures. The Holistic Complementary and Alternative Medicine Questionnaire (HCAMQ is one such measure. This article aimed to examine its construct validity, using a modern psychometric approach. The HCAMQ was completed by 221 patients (mean age 66.8, SD 8.29, 58% females with chronic stable pain predominantly from a single joint (hip or knee of mechanical origin, waiting for a hip (40% or knee (60% joint replacement, on enrolment in a study investigating the effects of acupuncture and placebo controls. The HCAMQ contains a Holistic Health (HH Subscale (five items and a CAM subscale (six items. Validity of the subscales was tested using Cronbach alpha's, factor analysis, Mokken scaling and Rasch analysis, which did not support the original two-factor structure of the scale. A five-item HH subscale and a four-item CAM subscale (worded in a negative direction fitted the Rasch model and were unidimensional (χ2=8.44, P=0.39, PSI=0.69 versus χ2=17.33, P=0.03, PSI=0.77. Two CAM items (worded in the positive direction had significant misfit. In conclusion, we have shown that the original two-factor structure of the HCAMQ could not be supported but that two valid shortened subscales can be used, one for HH Beliefs (four-item HH, and the other for CAM Beliefs (four-item CAM. It is recommended that consideration is given to rewording the two discarded positively worded CAM questions to enhance construct validity.

  19. HOLISTIC PROCEDURE WORK ORGANIZATION AND LABOR SKILLS

    Directory of Open Access Journals (Sweden)

    Marianela Bermejo-Salmon

    2016-01-01

    Full Text Available The purpose of this article is the development of a procedure with a holistic focus for the treatment of the elements that conform the profile of work organization in the United of Base Enterprise Mastor of the Telex Company of Santiago de Cuba. Different methods and techniques are used such as: historical-logical, analysis and synthesis, induction and deduction, the Delphi method, functional analysis, integrated focus or ¨Holistic¨, experts’ approach, briefcase or portfolio of evidences, surveys, and observation of the acting, among others. The procedure establishes two key moments for the study of the process given by the level of competitions and its profile. The competence tasks were identified and the rules and standards tasks from which a direct link between the performances evaluations and formations action is established, in correspondence with the elements that integrate the process of work organization with an integrative character. 

  20. The BOS-X approach: achieving drastic cost reduction in CPV through holistic power plant level innovation

    Science.gov (United States)

    Plesniak, A.; Garboushian, V.

    2012-10-01

    In 2011, the Amonix Advanced Technology Group was awarded DOE SunShot funding in the amount of 4.5M to design a new Balance of System (BOS) architecture utilizing Amonix MegaModules™ focused on reaching the SunShot goal of 0.06-$0.08/kWhr LCOE. The project proposal presented a comprehensive re-evaluation of the cost components of a utility scale CPV plant and identified critical areas of focus where innovation is needed to achieve cost reduction. As the world's premier manufacturer and most experienced installer of CPV power plants, Amonix is uniquely qualified to lead a rethinking of BOS architecture for CPV. The presentation will focus on the structure of the BOS-X approach, which looks for the next wave of cost reduction in CPV through evaluation of non-module subsystems and the interaction between subsystems during the lifecycle of a solar power plant. Innovation around nonmodule components is minimal to date because CPV companies are just now getting enough practice through completion of large projects to create ideas and tests on how to improve baseline designs and processes. As CPV companies increase their installed capacity, they can utilize an approach similar to the methodology of BOS-X to increase the competitiveness of their product. Through partnership with DOE, this holistic approach is expected to define a path for CPV well aligned with the goals of the SunShot Initiative.

  1. Philosophy for Children Meets the Art of Living: A Holistic Approach to an Education for Life

    Science.gov (United States)

    D'Olimpio, Laura; Teschers, Christoph

    2016-01-01

    This article explores the meeting of two approaches towards philosophy and education: the philosophy for children (P4C) approach advocated by Lipman and others, and Schmid's (2000a) philosophical concept of" Lebenskunst" (the art of living). Schmid explores the concept of the beautiful or good life by asking what is necessary for each…

  2. Holistic Approach as Viewed by the Basic School Teachers in Latvia

    Science.gov (United States)

    Badjanova, Jelena; Iliško, Dzintra

    2015-01-01

    The article points to new competencies required from basic school teachers, reinforced by the reform processes in the educational system in Latvia, the quality assurance of educational process, and modernisation and critical re-evaluation of educational materials and standards. The authors view sustainability as an integral part of reform…

  3. HOLISTIC MARKETING MANAGEMENT AND SOCIAL MEDIA

    OpenAIRE

    William PERTTULA

    2011-01-01

    Social media and social media marketing are real challenges to holistic marketing management approach focusing on real customer value. A distinct problem for social media is making a profit when the standard practice is to not charge the user any money. Social media marketing relies on its similarity to word of mouth marketing which has always been praised for its effectiveness. Social media marketing can be faster and cheaper that other forms of marketing, and should be integrated with the r...

  4. Systems Approaches: A Global and Historical Perspective on Integrative Medicine

    Science.gov (United States)

    2012-01-01

    The globalization of healing systems is a dance of cultural awareness and cultural dominance that has arisen throughout history. With the development of greater communication and interest in whole-systems approaches to healing, the opportunity for the development of a global perspective on healing has emerged with new life force. The birth of integrative holistic healing systems in the West, such as naturopathic, homeopathic, anthroposophic, integral and functional medicine, and others, echoes the ocean of wisdom present in traditional healing systems, such as traditional Chinese medicine (TCM) and Ayurveda. In working to integrate the lessons from these systems, we see the inextricable link between man and the natural world, we work to understand the root cause of disease, we focus on the whole person to return balance, and we use empiric observation in large populations over time to grasp the interrelationships inherent in the whole-systems view of illness and wellness. PMID:24278794

  5. An Integrated Approach to Biology

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 16; Issue 8. An Integrated Approach to Biology. Aniket Bhattacharya. General Article Volume 16 Issue 8 August 2011 pp 742-753. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/016/08/0742-0753 ...

  6. The understanding of Norwegian women’s sickness absence: towards a holistic approach?

    Directory of Open Access Journals (Sweden)

    Liv Johanne Solheim

    2011-11-01

    and adolescence that have made them vulnerable to domestic and work-related strains during their adult years. The study also indicates that women, especially single mothers, seem to be especially vulnerable to domestic strains, and that these strains may lead to a paradoxical pattern of women's sick leave: they take sick leave in order to deal with domestic strains along with the intention of prolonging their presence at the workplace in the longer term. Thus, these periods of sickness absence appear to be a necessary accompaniment of a high rate of participation among vulnerable groups in the labour market. Conclusion: Women's ill health and sickness absence should be understood as a manifestation of an interplay of the strains found at both the workplace and the home. A successful effort to reduce sickness absence in Norway, therefore, requires a holistic perspective that accounts for both the work and the domestic spheres. Normal 0 false false false EN-GB X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Vanlig tabell"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-fareast-language:EN-US;}

  7. Classification of follicular lymphoma images: a holistic approach with symbol-based machine learning methods.

    Science.gov (United States)

    Zorman, Milan; Sánchez de la Rosa, José Luis; Dinevski, Dejan

    2011-12-01

    It is not very often to see a symbol-based machine learning approach to be used for the purpose of image classification and recognition. In this paper we will present such an approach, which we first used on the follicular lymphoma images. Lymphoma is a broad term encompassing a variety of cancers of the lymphatic system. Lymphoma is differentiated by the type of cell that multiplies and how the cancer presents itself. It is very important to get an exact diagnosis regarding lymphoma and to determine the treatments that will be most effective for the patient's condition. Our work was focused on the identification of lymphomas by finding follicles in microscopy images provided by the Laboratory of Pathology in the University Hospital of Tenerife, Spain. We divided our work in two stages: in the first stage we did image pre-processing and feature extraction, and in the second stage we used different symbolic machine learning approaches for pixel classification. Symbolic machine learning approaches are often neglected when looking for image analysis tools. They are not only known for a very appropriate knowledge representation, but also claimed to lack computational power. The results we got are very promising and show that symbolic approaches can be successful in image analysis applications.

  8. Contractual framework of private-public partnership: The sui generis nature of PPP as a result of the holistic approach

    Directory of Open Access Journals (Sweden)

    Cvetković Predrag

    2014-01-01

    Full Text Available The holistic (comprehensive] approach to the methodological framework for the analysis of public-private partnership is essential presumption for the transformation of the public and private interests from the conflicting ones to the parallel and convergent ones. Private and public interests are to be regarded not as the divided particulars but as the element of the dynamics of PPP as a whole. The holistic approach facilitates interaction which brings new 'added values' in the exercise of the public interest by using the PPP construction: economic, social and political. This concept allows the PPP to 'take the best of both worlds' (the protection of the public interest and solidarity from the public sector, and the entrepreneurial logic from the private sector]. In light of the sui generis structure of mutual relations between the public and the private partner in the PPP framework, the contractual basis of public-private partnership has the character of relational contracts. Relational contracts differ from traditional contracting mechanisms. The parties to traditional contracts have equal information at their disposal, which enables them to define ex ante the terms of the transaction insofar as the consequences of performance or non-performance are anticipated at the time of contract conclusion. On the other hand, relational contracts are incomplete agreements: the parties to relational contracts mutually agree that it is impossible or economically inefficient to define ex ante the possible difficulties and circumstances of the transaction at issue (which is possible in classical contracts]. In this respect, in relational contracts the rationale for commitment is relatively flexible. The public-private partnership agreement is a relational contract. Relational contracts within the PPP framework limit the opportunistic behaviour on both parties and promote the development of their co-operation and exchange of information. Relational contracts

  9. Economical vehicle body in white concepts of series production. A holistic approach to technology trends under the aspect of the climate debate; Wirtschaftliche Fahrzeugleichtbaukonzepte grosser Baureihen. Ein holistischer Ansatz zu Technologietrends im Rahmen der Klimadebatte

    Energy Technology Data Exchange (ETDEWEB)

    Klose, Peter L.M. [MBtech Consulting GmbH, Sindelfingen (Germany). Bereich ' Innovations- und Technologiemanagement' ; Gaenzle, Steffen [MBtech Consulting GmbH, Sindelfingen (Germany). Lean Development and Launch Consulting

    2009-07-01

    Automotive light weight construction does not only mean to choose light weight materials. It is also an integrated concept and therefore the consideration of interactions for whole chain of vehicle development is required. The inter-dependencies and demands of raw material suppliers, fabricators, system suppliers and vehicle manufacturers will be outlined. An insight into the most important trends of automotive body in white construction methods, material concepts, joining technologies on a holistic system overview will be given. Approaches of an economic implementation through build up of system alliances between OEM/suppliers and refinancing of development costs during generation programs will be pointed out. (orig.)

  10. Holistic Experimentation for Emergence: A Creative Approach to Postgraduate Entrepreneurship Education and Training

    Science.gov (United States)

    Mitra, Jay

    2017-01-01

    This article explores the development of a comprehensive and systemic approach to entrepreneurship education at a research-intensive university in the United Kingdom. The exploration is based on two key conceptual challenges: (a) taking entrepreneurship to mean something more than new business creation and (b) differentiating between…

  11. Anything Can Happen out There: A Holistic Approach to Field Trips

    Science.gov (United States)

    Plutino, Alessia

    2016-01-01

    This paper looks back at an academic-led language field trip project, now in its third year, involving ab-initio students of Italian at the University of Southampton. It considers the role of academic-led field trips in Modern Languages (ML) and it explores the underlying pedagogical approaches that were adopted to enhance students' engagement,…

  12. A Holistic Approach to Delivering Sustainable Design Education in Civil Engineering

    Science.gov (United States)

    Vemury, Chandra Mouli; Heidrich, Oliver; Thorpe, Neil; Crosbie, Tracey

    2018-01-01

    Purpose: The purpose of this paper is to present pedagogical approaches developed and implemented to deliver sustainable design education (SDE) to second-year undergraduate students on civil engineering programmes in the (then) School of Civil Engineering and Geosciences at Newcastle University. In doing so, the work presented offers an example of…

  13. A Holistic Approach to Supporting the Learning of Young Indigenous Students: One Case Study

    Science.gov (United States)

    Warren, Elizabeth; Quine, Janine

    2013-01-01

    Due to the high turnover of teaching staff in remote schools, the long-term sustainability of educational initiatives that enhance Indigenous student's learning is a major concern. This article presents a study of a remote Indigenous school (Ischool) situated in Queensland. Ischool has changed its approach to leadership, particularly the…

  14. A holistic approach to CAKUT (Congenital Anomalies of the Kidney and Urinary Tract

    Directory of Open Access Journals (Sweden)

    Giuseppe Masnata

    2016-02-01

    Full Text Available The urinary tract malformations, today called CAKUT (Congenital Anomalies of the Kidney and Urinary Tract, include a range of morphological and/or functional abnormalities of the kidney and urinary tract diseases, apart from being the main cause of renal failure in children. The frequency of these birth defects is around 2% of pregnancies and many genetic syndromes may include CAKUT: about 500 of them have been described. The CAKUT concern localized alterations at different levels of the urinary system: hydronephrosis, vesicoureteral reflux, duplex collecting system, megaureter, kidney dysplasia. In the approach to the child with CAKUT it is important to identify a population at risk, distinguishing between CAKUT with and without clinical significance, applying a tailored approach to the individual patient, avoiding unnecessary investigations and treatments.

  15. Analytical approach to landside system dynamics at airport passenger terminals: departmentalization and holistic view

    OpenAIRE

    Montesinos Ferrer, Marti

    2016-01-01

    Airport landside system is complex, with multiple interrelations. Currently, each facility is managed locally without a systemic view. This study analyzes the impact of different resource management policies on the overall system performance (embarking direction). The results are derived from an analytical approach, based on queueing theory, which allows investigating different time-varying resource allocation policies at each processing facility and its impact on system dynamics.

  16. A holistic approach to SIM platform and its application to early-warning satellite system

    Science.gov (United States)

    Sun, Fuyu; Zhou, Jianping; Xu, Zheyao

    2018-01-01

    This study proposes a new simulation platform named Simulation Integrated Management (SIM) for the analysis of parallel and distributed systems. The platform eases the process of designing and testing both applications and architectures. The main characteristics of SIM are flexibility, scalability, and expandability. To improve the efficiency of project development, new models of early-warning satellite system were designed based on the SIM platform. Finally, through a series of experiments, the correctness of SIM platform and the aforementioned early-warning satellite models was validated, and the systematical analyses for the orbital determination precision of the ballistic missile during its entire flight process were presented, as well as the deviation of the launch/landing point. Furthermore, the causes of deviation and prevention methods will be fully explained. The simulation platform and the models will lay the foundations for further validations of autonomy technology in space attack-defense architecture research.

  17. Girls’ education in Djibouti: an holistic approach in response to the ideology of development

    Directory of Open Access Journals (Sweden)

    Rachel Solomon Tsehaye

    2012-10-01

    Full Text Available In a cross between gender sociology, education sciences and politic anthropology, this research takes an interest in the complementarity of scientific and methodological approaches, through a study on pupils of Djibouti, in order to extricate from a negative interpretation of the limited girl schooling process in African contexts. In the aftermath of the immersion work to which this enquiry refers, the idealization which hide behind the promotion of girls’ education which need to be questioned and which give rise a better understanding of the persistence of the «afropessimistic» analysis in the expert’s reports or in the scientific literature.

  18. Hemangiosarcoma in a Dog: Unusual Presentation and Increased Survival Using a Complementary/Holistic Approach Combined with Metronomic Chemotherapy

    Directory of Open Access Journals (Sweden)

    Philip Chaikin

    2018-01-01

    Full Text Available This case report documents the clinical and pathologic findings in a 12-year-old terrier mix with intraocular and splenic hemangiosarcoma. Pathologic findings in both the spleen and globe were consistent with hemangiosarcoma with a low mitotic count. Initial treatment consisted of enucleation and then splenectomy followed by one cycle of conventional doxorubicin chemotherapy. Due to poor tolerance, a subsequent treatment regimen consisted of metronomic chemotherapy with chlorambucil combined with an alternative/complementary regimen of I’m-Yunity (polysaccharopeptide and Yunnan Baiyao. Follow-up thoracic radiographs and abdominal ultrasounds over a period of 24 months showed no evidence of pulmonary, hepatic, or right atrial metastases, during which time the patient had an excellent quality of life. However, shortly after achieving two-year survival, the patient developed new onset seizures unresponsive to anticonvulsant therapy. Therefore, a decision was made to euthanize the dog given that the most likely etiology of the seizures was a brain tumor. Overall, this is an exceptional treatment response given the poor survival statistics of hemangiosarcoma even with conventional chemotherapy. However, additional clinical pharmacology and clinical trial data are needed to further support the use of a complementary/holistic approach in combination with metronomic chemotherapy.

  19. What prevents Chinese parents from reporting possible cases of child sexual abuse to authority? A holistic-interactionistic approach.

    Science.gov (United States)

    Xie, Qian Wen; Sun, Xiaoyue; Chen, Mengtong; Qiao, Dong Ping; Chan, Ko Ling

    2017-02-01

    The reporting of suspected CSA cases to authorities in a timely manner is important in preventing continued abuse and protecting abused children at early ages. The current study seeks to explore parents' intentions of reporting their own children's CSA experiences to authorities as well as their reporting willingness when they become aware of possible CSA cases happening to children in other families. Two rounds of semi-structured interviews were conducted among a sample of 26 parents in Beijing; these parents were purposefully selected so as to be diverse in terms of gender, age, and socioeconomic status. The data were analyzed thematically. The findings showed that the reporting of suspected CSA to authorities was a choice made by only a few Chinese parents; it was often even a last resort. By using a holistic-interactionistic approach, the interaction between Chinese parents' intentions of reporting CSA and the Chinese socio-cultural context was analyzed as a dynamic and continuously ongoing process. The impacts of the definition and perceptions of CSA on reporting, the balance of children's rights and parents' power, and the double effect of informal social control are discussed. The implications, both locally and globally, are also discussed. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. A holistic approach to dissecting SPARC family protein complexity reveals FSTL-1 as an inhibitor of pancreatic cancer cell growth.

    Science.gov (United States)

    Viloria, Katrina; Munasinghe, Amanda; Asher, Sharan; Bogyere, Roberto; Jones, Lucy; Hill, Natasha J

    2016-11-25

    SPARC is a matricellular protein that is involved in both pancreatic cancer and diabetes. It belongs to a wider family of proteins that share structural and functional similarities. Relatively little is known about this extended family, but evidence of regulatory interactions suggests the importance of a holistic approach to their study. We show that Hevin, SPOCKs, and SMOCs are strongly expressed within islets, ducts, and blood vessels, suggesting important roles for these proteins in the normal pancreas, while FSTL-1 expression is localised to the stromal compartment reminiscent of SPARC. In direct contrast to SPARC, however, FSTL-1 expression is reduced in pancreatic cancer. Consistent with this, FSTL-1 inhibited pancreatic cancer cell proliferation. The complexity of SPARC family proteins is further revealed by the detection of multiple cell-type specific isoforms that arise due to a combination of post-translational modification and alternative splicing. Identification of splice variants lacking a signal peptide suggests the existence of novel intracellular isoforms. This study underlines the importance of addressing the complexity of the SPARC family and provides a new framework to explain their controversial and contradictory effects. We also demonstrate for the first time that FSTL-1 suppresses pancreatic cancer cell growth.

  1. The future of monitoring in clinical research - a holistic approach: linking risk-based monitoring with quality management principles.

    Science.gov (United States)

    Ansmann, Eva B; Hecht, Arthur; Henn, Doris K; Leptien, Sabine; Stelzer, Hans Günther

    2013-01-01

    Since several years risk-based monitoring is the new "magic bullet" for improvement in clinical research. Lots of authors in clinical research ranging from industry and academia to authorities are keen on demonstrating better monitoring-efficiency by reducing monitoring visits, monitoring time on site, monitoring costs and so on, always arguing with the use of risk-based monitoring principles. Mostly forgotten is the fact, that the use of risk-based monitoring is only adequate if all mandatory prerequisites at site and for the monitor and the sponsor are fulfilled.Based on the relevant chapter in ICH GCP (International Conference on Harmonisation of technical requirements for registration of pharmaceuticals for human use - Good Clinical Practice) this publication takes a holistic approach by identifying and describing the requirements for future monitoring and the use of risk-based monitoring. As the authors are operational managers as well as QA (Quality Assurance) experts, both aspects are represented to come up with efficient and qualitative ways of future monitoring according to ICH GCP.

  2. First Approach to a Holistic Tool for Assessing RES Investment Feasibility

    Directory of Open Access Journals (Sweden)

    José María Flores-Arias

    2018-04-01

    Full Text Available Combining availability, viability, sustainability, technical options, and environmental impact in an energy-planning project is a difficult job itself for the today’s engineers. This becomes harder if the potential investors also need to be persuaded. Moreover, the problem increases even more if various consumptions are considered, as their patterns depend to a large extent on the type of facility and the activity. It is therefore essential to develop tools to assess the balance between generation and demand in a given installation. In this paper, a valuable tool is developed for the seamless calculation of the integration possibilities of renewable energies and the assessment of derived technical, financial and environmental impacts. Furthermore, it also considers their interaction with the power grid or other networks, raising awareness of the polluting emissions responsible for global warming. Through a series of Structured Query Language databases and a dynamic data parameterization, the software is provided with sufficient information to encode, calculate, simulate and graphically display information on the generation and demand of electric, thermal and transport energy, all in a user-friendly environment, finally providing an evaluation and feasibility report.

  3. Poverty, Socio-Political Factors and Degradation of the Environment in Sub-Saharan Africa: The Need For a Holistic Approach to the Protection of the Environment and Realisation of the Right to Environment

    Directory of Open Access Journals (Sweden)

    Emeka Polycarp Amechi

    2009-09-01

    Full Text Available The right to environment is a recognised human right in Africa. However, despite the legal and institutional frameworks designed to respect, promote, protect and fulfil the right, its enjoyment is still a mirage to majority of African citizens as a result of environmental degradation. This article aims to proffer a holistic or integrated approach to tackling the problem of environmental degradation in sub-Saharan Africa in order to enhance the protection of the environment and the realisation of this right in the region. It recognises that the problem of environmental degradation in the region is not due to lack of regulatory frameworks, but rather due to other factors that are mainly socio-economic and political in nature. It argues that to enhance the protection of the environment and realisation of this right in sub-Saharan Africa, African governments must adopt a holistic approach towards the protection of the environment, and proposes the promotion of good governance and socio-economic reform in the region as an integral core of such approach.

  4. Clinical holistic medicine: holistic adolescent medicine.

    Science.gov (United States)

    Ventegodt, Søren; Morad, Mohammed; Press, Joseph; Merrick, Joav; Shek, Daniel T L

    2004-08-04

    The holistic medical approach seems to be efficient and can also be used in adolescent medicine. Supporting the teenager to grow and develop is extremely important in order to prevent many of the problems they can carry into adulthood. The simple consciousness-based, holistic medicine--giving love, winning trust, giving holding, and getting permission to help the patient feel, understand, and let go of negative beliefs--is easy for the physician interested in this kind of practice and it requires little previous training for the physician to be able to care for his/her patient. A deeper insight into the principles of holistic treatment and a thorough understanding of our fellow human beings are making it work even better. Holistic medicine is not a miracle cure, but rather a means by which the empathic physician can support the patient in improving his/her future life in respect to quality of life, health, and functional capacity--through coaching the patient to work on him/herself in a hard and disciplined manner. When the patient is young, this work is so much easier. During our lifetime, we have several emotional traumas arranged in the subconscious mind with the smallest at the top, and it is normal for the person to work on a large number of traumatic events that have been processed to varying degrees. Some traumas have been acknowledged, some are still being explored by the person, and yet others are still preconscious, which can be seen for example in the form of muscle tension. Sometimes the young dysfunctional patient carries severe traumas of a violent or sexual nature, but the physician skilled in the holistic medical toolbox can help the patient on his/her way to an excellent quality of life, full self-expression, a love and sex life, and a realization of his/her talents--all that a young patient is typically dreaming about. Biomedicine is not necessary or even recommended when the physical or mental symptoms are caused by disturbances in the personal

  5. Clinical Holistic Medicine: Holistic Adolescent Medicine

    Directory of Open Access Journals (Sweden)

    Søren Ventegodt

    2004-01-01

    Full Text Available The holistic medical approach seems to be efficient and can also be used in adolescent medicine. Supporting the teenager to grow and develop is extremely important in order to prevent many of the problems they can carry into adulthood. The simple consciousness-based, holistic medicine — giving love, winning trust, giving holding, and getting permission to help the patient feel, understand, and let go of negative beliefs — is easy for the physician interested in this kind of practice and it requires little previous training for the physician to be able to care for his/her patient. A deeper insight into the principles of holistic treatment and a thorough understanding of our fellow human beings are making it work even better. Holistic medicine is not a miracle cure, but rather a means by which the empathic physician can support the patient in improving his/her future life in respect to quality of life, health, and functional capacity — through coaching the patient to work on him/herself in a hard and disciplined manner. When the patient is young, this work is so much easier. During our lifetime, we have several emotional traumas arranged in the subconscious mind with the smallest at the top, and it is normal for the person to work on a large number of traumatic events that have been processed to varying degrees. Some traumas have been acknowledged, some are still being explored by the person, and yet others are still preconscious, which can be seen for example in the form of muscle tension. Sometimes the young dysfunctional patient carries severe traumas of a violent or sexual nature, but the physician skilled in the holistic medical toolbox can help the patient on his/her way to an excellent quality of life, full self-expression, a love and sex life, and a realization of his/her talents — all that a young patient is typically dreaming about. Biomedicine is not necessary or even recommended when the physical or mental symptoms are caused

  6. A Holistic Approach with Special Reference to Heat Transfer in Multi-Component Porous Media Systems

    Directory of Open Access Journals (Sweden)

    A. K. Borah

    2010-06-01

    Full Text Available Problems involving multiphase flow, heat transfer and multi-component mass transport in porous media arise in a number of scientific engineering disciplines. Important technological applications include thermally enhanced oil recovery, subsurface contamination and remediation, capillary assisted thermal technologies, drying process, thermal insulation materials, multiphase trickle bed reactors, nuclear reactor safety analysis, high level radioactive waste repositories and geothermal energy exploitation. In this paper we demonstrate multiphase flows in porous media are driven by gravitational, capillary and viscous forces. But gravity causes phase migration in the direction of the gravitational field. Microscopic modelling efforts were made to accurately incorporate microscopic interfacial phenomena. Multi-scale modelling approaches were attempted in order to transmit information over various lengths scales, ranging from micro-scale, meso-scale, macro-scale and finally to the field scale.

  7. Smart and Sustainable Offices (SSO: Showcasing a holistic approach to realise the next generation offices

    Directory of Open Access Journals (Sweden)

    A. Cobaleda Cordero

    2018-01-01

    Full Text Available The Smart Sustainable Offices project (SSO is a product of years of research with large sets of data collected from more than 30 office buildings in Switzerland, Sweden, and Spain. Based on scientific evidence, the concept of SSO, initially conceived as a research plan to address the interdependencies between office users and their working environment in a European context, is now used as a qualitative and quantitative mixed method approach for office diagnosis and ideation. At the current stage, the SSO methodology aims to implement a new paradigm of user-oriented, lower carbon footprint and resilient office design solutions. The main strategy is articulated around the “office DNA” of every organisation, decoded as a compound of work patterns, operational and individual needs, and their potential to define design criteria. The practical application of SSO and its tentative findings exemplified through three pilot test office-demonstrators are described in this paper.

  8. Holistic Medicine: Advances and Shortcomings

    OpenAIRE

    Shapiro, Edward

    1982-01-01

    Holistic medicine is an attitudinal approach to health care rather than a particular set of techniques. It addresses the psychological, familial, societal, ethical and spiritual as well as biological dimensions of health and illness. The holistic approach emphasizes the uniqueness of each patient, the mutuality of the doctor-patient relationship, each person's responsibility for his or her own health care and society's responsibility for the promotion of health.

  9. Holistic and consumer-centric assessment of beer: A multi-measurement approach.

    Science.gov (United States)

    Jaeger, Sara R; Cardello, Armand V; Chheang, Sok L; Beresford, Michelle K; Hedderley, Duncan I; Pineau, Benedicte

    2017-09-01

    Despite occupying a cornerstone position in consumer research and innovation, product liking/disliking provides only partial insight into consumer behaviour. By adopting a consumer-centric perspective and drawing on additional factors that underpin food-related consumer behaviour, a more complete product understanding is gained. The present research showcases this approach in a study with New Zealand beer (incl. pilsner, lager and ale categories). Implementation of a multi-variate approach with 128 regular beer drinkers provided assessments pertaining to liking and sensory novelty/complexity, situational appropriateness of consumption, as well as attitudes/perceptions and emotional associations. The 9 samples grouped into two clusters, where 4 of the beers were similar in being perceived as having less complex flavours, being appropriate for many uses and evoking stronger emotional associations of "relaxed/calm." The 4 beers were perceived as "easy to drink", and were, on average, most liked. One of the samples in this cluster was lighter in alcohol (2.5% ABV), but not inferior to beers with 4-5% ABV. The 5 beers in the second cluster were, on average, less liked and were associated with more negative emotions, e.g. "unhappy, "jittery", and "tense". Additional insights were gained from segmentation which identified two groups of consumers, named 'Lager Lovers' and 'Ale Aficionados'. Beers 1-4 were positively perceived by 'Lager Lovers' but less so by 'Ale Aficionados', and vice versa. The study was conducted under central location test conditions compatible with testing protocols often used in product research. The study protocol can be amended to include few/many consumer-centric measures and extended to product testing where packaging, brand, and other extrinsic information is available to consumers. Copyright © 2017 Elsevier Ltd. All rights reserved.

  10. Ares I Integrated Test Approach

    Science.gov (United States)

    Taylor, Jim

    2008-01-01

    This slide presentation reviews the testing approach that NASA is developing for the Ares I launch vehicle. NASA is planning a complete series of development, qualification and verification tests. These include: (1) Upper stage engine sea-level and altitude testing (2) First stage development and qualification motors (3) Upper stage structural and thermal development and qualification test articles (4) Main Propulsion Test Article (MPTA) (5) Upper stage green run testing (6) Integrated Vehicle Ground Vibration Testing (IVGVT) and (7) Aerodynamic characterization testing.

  11. A holistic approach to study the effects of natural antioxidants on inflammation and liver cancer.

    Science.gov (United States)

    Costantini, Susan; Colonna, Giovanni; Castello, Giuseppe

    2014-01-01

    The limited effectiveness of chemotherapy and the high recurrence rate of cancers highlight the urgent need to identify new molecular targets and to develop new treatments. Numerous epidemiological studies have recently highlighted the existence of an inverse association between fruit and vegetable consumption, natural antioxidants, and cancer risk; in fact, antioxidant intake through diet or supplements of plant origin is strongly recommended for cancer prevention and cure. In general, antioxidants are substances of vegetable, mineral, or animal origin that neutralize free radicals and protect the body from their negative actions on the plasma membrane, proteins, and DNA. Hence, cancer can be prevented by the stimulation of the immune system to destroy cancer cells or to block their proliferation. Since living organisms may be studied as a whole complex system by the "omics sciences" which tend toward understanding and describing the global information of genes, mRNA, proteins, and metabolites, our aim is to use bioinformatics and systems biology to study cytokinome, which plays an important role in the evolution of inflammatory processes and is also a key component in the evolution of cancer, a disease recognized as depending on chronic inflammation and also with the concomitant presence of type 2 diabetes and obesity. On the whole, we define cytokinome as the totality of these proteins and their interactions in and around biological cells. Understanding the complex interaction network of cytokines in patients affected by cancers should be very useful both to follow the evolution of cancer from its early stages and to define innovative therapeutic strategies by using systems biology approaches. In this paper, we review some results of our group in the light of the "omics" logic, and in particular (1) the need for a global approach to study complex systems such as multifactorial cancer and, in particular, hepatocellular carcinoma, (2) the correlation between

  12. Holistic risk assessment and risk prevention approach to the mechanized NDT and the inspection procedure

    International Nuclear Information System (INIS)

    Bertovic, Marija; Mueller, Christina; Fahlbruch, Babette; Ronneteg, Ulf; Pitkaenen, Jorma

    2013-01-01

    The difficulty to deal with human factors in non-destructive testing (NDT) stems from their diversity and complexity - no single human or organizational factor is responsible for the entire fluctuations in the NDT performance. The typical approach to decrease the variability in the inspection results had been found in replacing manual NDT with mechanized methods. However, even though some human errors can be avoided by automating the process, there are new risks that can arise from its application and need to be further investigated. To address this problem, a combination of theoretical and practical approaches should be applied, where the source of error is not seen only in the inspector, but also in his interaction with social and technical systems, as well as the organization. An analysis of potential risks in the use of mechanized inspections methods for spent fuel canisters has shown potential for human error in acquisition, as well as in the evaluation of the gathered results. Assessed causes of those errors lay in the inspector, but also in the organization and in shortcomings of the inspection procedure. The aim of the analysis was to provide with preventive measures and optimization recommendations. Those include further automation of the process, application of human redundancy, improvements of the inspection procedure, hardware and software improvements etc. Before improvements can be made, there is a need to understand the resulting processes and the influence of their interaction on the inspection results. The results have shown that when working with an automated system, one must avoid over relying on its proper functioning and form appropriate trust towards automation. Furthermore, human redundancy should be applied only in cases where the redundant inspectors are completely unaware of each other, in order to avoid the effects of social loafing and shirking. The inspection procedure is one of the most important tools in the application of NDT. On an

  13. Holistic risk assessment and risk prevention approach to the mechanized NDT and the inspection procedure

    Energy Technology Data Exchange (ETDEWEB)

    Bertovic, Marija; Mueller, Christina [Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin (Germany); Fahlbruch, Babette [TUEV NORD Systems GmbH und Co. KG, Berlin (Germany); Ronneteg, Ulf [SKB Swedish Nuclear Fuel and Waste Management Co., Oskarshamn (Sweden); Pitkaenen, Jorma [Posiva Oy, Eurajoki (Finland)

    2013-07-01

    The difficulty to deal with human factors in non-destructive testing (NDT) stems from their diversity and complexity - no single human or organizational factor is responsible for the entire fluctuations in the NDT performance. The typical approach to decrease the variability in the inspection results had been found in replacing manual NDT with mechanized methods. However, even though some human errors can be avoided by automating the process, there are new risks that can arise from its application and need to be further investigated. To address this problem, a combination of theoretical and practical approaches should be applied, where the source of error is not seen only in the inspector, but also in his interaction with social and technical systems, as well as the organization. An analysis of potential risks in the use of mechanized inspections methods for spent fuel canisters has shown potential for human error in acquisition, as well as in the evaluation of the gathered results. Assessed causes of those errors lay in the inspector, but also in the organization and in shortcomings of the inspection procedure. The aim of the analysis was to provide with preventive measures and optimization recommendations. Those include further automation of the process, application of human redundancy, improvements of the inspection procedure, hardware and software improvements etc. Before improvements can be made, there is a need to understand the resulting processes and the influence of their interaction on the inspection results. The results have shown that when working with an automated system, one must avoid over relying on its proper functioning and form appropriate trust towards automation. Furthermore, human redundancy should be applied only in cases where the redundant inspectors are completely unaware of each other, in order to avoid the effects of social loafing and shirking. The inspection procedure is one of the most important tools in the application of NDT. On an

  14. Intent, Capability and Opportunity: A Holistic Approach to Addressing Proliferation as a Risk Management Issue

    Energy Technology Data Exchange (ETDEWEB)

    Amanda Rynes; Trond Bjornard

    2011-07-01

    Currently, proliferation risk assessment models are designed to evaluate only a portion of the overall risk, focusing exclusively on either technological or social factors to determine the extent of a threat. Many of these models are intended to act as a means of predicting proliferation potential rather than assessing the system as a whole, ignoring the ability to enhance mitigating factors and manage, rather just establish the presence of, the threat. While the information garnered through these forms of analysis is necessary, it remains incomplete. By incorporating political, social, economic and technical capabilities as well as human factors such as intent into a single, multi-faceted risk management model, proliferation risk can be evaluated more effectively. Framing this information around how to improve and expand the Regime already in place and establishing where there are gaps in the system allows for a more complete approach to risk management, mitigation and resource allocation. The research conducted here seeks to combine all three elements (intent, capability and opportunity) in a comprehensive evaluation which incorporates an assessment of state-level variables, possible proliferation pathways and technical capability. Each portion of the analysis is carried out independently then combined to illustrate the full scope of a State's nuclear infrastructure while showing areas of weakness in the institutional framework.

  15. Holistic approach for automated background EEG assessment in asphyxiated full-term infants

    Science.gov (United States)

    Matic, Vladimir; Cherian, Perumpillichira J.; Koolen, Ninah; Naulaers, Gunnar; Swarte, Renate M.; Govaert, Paul; Van Huffel, Sabine; De Vos, Maarten

    2014-12-01

    Objective. To develop an automated algorithm to quantify background EEG abnormalities in full-term neonates with hypoxic ischemic encephalopathy. Approach. The algorithm classifies 1 h of continuous neonatal EEG (cEEG) into a mild, moderate or severe background abnormality grade. These classes are well established in the literature and a clinical neurophysiologist labeled 272 1 h cEEG epochs selected from 34 neonates. The algorithm is based on adaptive EEG segmentation and mapping of the segments into the so-called segments’ feature space. Three features are suggested and further processing is obtained using a discretized three-dimensional distribution of the segments’ features represented as a 3-way data tensor. Further classification has been achieved using recently developed tensor decomposition/classification methods that reduce the size of the model and extract a significant and discriminative set of features. Main results. Effective parameterization of cEEG data has been achieved resulting in high classification accuracy (89%) to grade background EEG abnormalities. Significance. For the first time, the algorithm for the background EEG assessment has been validated on an extensive dataset which contained major artifacts and epileptic seizures. The demonstrated high robustness, while processing real-case EEGs, suggests that the algorithm can be used as an assistive tool to monitor the severity of hypoxic insults in newborns.

  16. Holistic approach to prevention and management of type 2 diabetes mellitus in a family setting.

    Science.gov (United States)

    Ofori, Sandra N; Unachukwu, Chioma N

    2014-01-01

    Diabetes mellitus (DM) is a chronic, progressive metabolic disorder with several complications that affect virtually all the systems in the human body. Type 2 DM (T2DM) is a major risk factor for cardiovascular disease (CVD). The management of T2DM is multifactorial, taking into account other major modifiable risk factors, like obesity, physical inactivity, smoking, blood pressure, and dyslipidemia. A multidisciplinary team is essential to maximize the care of individuals with DM. DM self-management education and patient-centered care are the cornerstones of management in addition to effective lifestyle strategies and pharmacotherapy with individualization of glycemic goals. Robust evidence supports the effectiveness of this approach when implemented. Individuals with DM and their family members usually share a common lifestyle that, not only predisposes the non-DM members to developing DM but also, increases their collective risk for CVD. In treating DM, involvement of the entire family, not only improves the care of the DM individual but also, helps to prevent the risk of developing DM in the family members.

  17. Holistic approach to prevention and management of type 2 diabetes mellitus in a family setting

    Directory of Open Access Journals (Sweden)

    Ofori SN

    2014-05-01

    Full Text Available Sandra N Ofori, Chioma N Unachukwu Department of Internal Medicine, University of Port Harcourt Teaching Hospital, Port Harcourt, Rivers State, Nigeria Abstract: Diabetes mellitus (DM is a chronic, progressive metabolic disorder with several complications that affect virtually all the systems in the human body. Type 2 DM (T2DM is a major risk factor for cardiovascular disease (CVD. The management of T2DM is multifactorial, taking into account other major modifiable risk factors, like obesity, physical inactivity, smoking, blood pressure, and dyslipidemia. A multidisciplinary team is essential to maximize the care of individuals with DM. DM self-management education and patient-centered care are the cornerstones of management in addition to effective lifestyle strategies and pharmacotherapy with individualization of glycemic goals. Robust evidence supports the effectiveness of this approach when implemented. Individuals with DM and their family members usually share a common lifestyle that, not only predisposes the non-DM members to developing DM but also, increases their collective risk for CVD. In treating DM, involvement of the entire family, not only improves the care of the DM individual but also, helps to prevent the risk of developing DM in the family members. Keywords: cardiovascular disease, multifactorial management

  18. Intent, Capability and Opportunity: A Holistic Approach to Addressing Proliferation as a Risk Management Issue

    International Nuclear Information System (INIS)

    Rynes, Amanda; Bjornard, Trond

    2011-01-01

    Currently, proliferation risk assessment models are designed to evaluate only a portion of the overall risk, focusing exclusively on either technological or social factors to determine the extent of a threat. Many of these models are intended to act as a means of predicting proliferation potential rather than assessing the system as a whole, ignoring the ability to enhance mitigating factors and manage, rather just establish the presence of, the threat. While the information garnered through these forms of analysis is necessary, it remains incomplete. By incorporating political, social, economic and technical capabilities as well as human factors such as intent into a single, multi-faceted risk management model, proliferation risk can be evaluated more effectively. Framing this information around how to improve and expand the Regime already in place and establishing where there are gaps in the system allows for a more complete approach to risk management, mitigation and resource allocation. The research conducted here seeks to combine all three elements (intent, capability and opportunity) in a comprehensive evaluation which incorporates an assessment of state-level variables, possible proliferation pathways and technical capability. Each portion of the analysis is carried out independently then combined to illustrate the full scope of a State's nuclear infrastructure while showing areas of weakness in the institutional framework.

  19. Waste management and the holistic fuel cycle

    International Nuclear Information System (INIS)

    Holmes, R.G.G.; Robbins, R.A.; Eilbeck, A.

    1996-01-01

    This paper outlines a holistic approach to the nuclear fuel cycle and the impact that waste management can have on the holistic approach. The philosophy includes regarding irradiated fuel as a resource rather than a waste that can be used as a source of fissile material to be recycled, either Uranium returned to fuel or Plutonium in mixed oxide fuels (MOX) for fast and impact of those compounds that leave the cycle (solid waste, liquid effluent and gaseous effluent) are minimized. This can only be achieved by applying a full life cycle analysis of process benefits. The paper describes some of the work in waste management but notes that waste and its generation must be seen as an integral part of any developed strategy. (authors)

  20. Novel Holistic Approaches for Overcoming Therapy Resistance in Pancreatic and Colon Cancers.

    Science.gov (United States)

    Sarkar, Fazlul H

    2016-01-01

    Gastrointestinal (GI) cancers, such as of the colon and pancreas, are highly resistant to both standard and targeted therapeutics. Therapy-resistant and heterogeneous GI cancers harbor highly complex signaling networks (the resistome) that resist apoptotic programming. Commonly used gemcitabine or platinum-based regimens fail to induce meaningful (i.e. disease-reversing) perturbations in the resistome, resulting in high rates of treatment failure. The GI cancer resistance networks are, in part, due to interactions between parallel signaling and aberrantly expressed microRNAs (miRNAs) that collectively promote the development and survival of drug-resistant cancer stem cells with epithelial-to-mesenchymal transition (EMT) characteristics. The lack of understanding of the resistance networks associated with this subpopulation of cells as well as reductionist, single protein-/pathway-targeted approaches have made 'effective drug design' a difficult task. We propose that the successful design of novel therapeutic regimens to target drug-resistant GI tumors is only possible if network-based drug avenues and agents, in particular 'natural agents' with no known toxicity, are correctly identified. Natural agents (dietary agents or their synthetic derivatives) can individually alter miRNA profiles, suppress EMT pathways and eliminate cancer stem-like cells that derive from pancreatic cancer and colon cancer, by partially targeting multiple yet meaningful networks within the GI cancer resistome. However, the efficacy of these agents as combinations (e.g. consumed in the diet) against this resistome has never been studied. This short review article provides an overview of the different challenges involved in the understanding of the GI resistome, and how novel computational biology can help in the design of effective therapies to overcome resistance. © 2015 S. Karger AG, Basel.

  1. Depression, body mass index, and chronic obstructive pulmonary disease – a holistic approach

    Directory of Open Access Journals (Sweden)

    Catalfo G

    2016-02-01

    Full Text Available Giuseppe Catalfo,1 Luciana Crea,1 Tiziana Lo Castro,1 Francesca Magnano San Lio,1 Giuseppe Minutolo,1 Gherardo Siscaro,2 Noemi Vaccino,1 Nunzio Crimi,3 Eugenio Aguglia1 1Department of Psychiatry, Policlinico “G. Rodolico” University Hospital, University of Catania, Catania, Italy; 2Operative Unit Neurorehabilitation, IRCCS Fondazione Salvatore Maugeri, Sciacca, Italy; 3Department of Pneumology, Policlinico “G. Rodolico” University Hospital, University of Catania, Catania, Italy Background: Several clinical studies suggest common underlying pathogenetic mechanisms of COPD and depressive/anxiety disorders. We aim to evaluate psychopathological and physical effects of aerobic exercise, proposed in the context of pulmonary rehabilitation, in a sample of COPD patients, through the correlation of some psychopathological variables and physical/pneumological parameters. Methods: Fifty-two consecutive subjects were enrolled. At baseline, the sample was divided into two subgroups consisting of 38 depression-positive and 14 depression-negative subjects according to the Hamilton Depression Rating Scale (HAM-D. After the rehabilitation treatment, we compared psychometric and physical examinations between the two groups. Results: The differences after the rehabilitation program in all assessed parameters demonstrated a significant improvement in psychiatric and pneumological conditions. The reduction of BMI was significantly correlated with fat mass but only in the depression-positive patients. Conclusion: Our results suggest that pulmonary rehabilitation improves depressive and anxiety symptoms in COPD. This improvement is significantly related to the reduction of fat mass and BMI only in depressed COPD patients, in whom these parameters were related at baseline. These findings suggest that depressed COPD patients could benefit from a rehabilitation program in the context of a multidisciplinary approach. Keywords: COPD, depression, aerobic exercise

  2. A holistic approach to healthy ageing: how can people live longer, healthier lives?

    Science.gov (United States)

    Calder, P C; Carding, S R; Christopher, G; Kuh, D; Langley-Evans, S C; McNulty, H

    2018-06-03

    Although lifespan is increasing, there is no evidence to suggest that older people are experiencing better health in their later years than previous generations. Nutrition, at all stages of life, plays an important role in determining health and wellbeing. A roundtable meeting of UK experts on nutrition and ageing considered key aspects of the diet-ageing relationship and developed a consensus position on the main priorities for research and public health actions that are required to help people live healthier lives as they age. The group consensus highlighted the requirement for a life course approach, recognising the multifactorial nature of the impact of ageing. Environmental and lifestyle influences at any life stage are modified by genetic factors and early development. The response to the environment at each stage of life can determine the impact of lifestyle later on. There are no key factors that act in isolation to determine patterns of ageing and it is a combination of environmental and social factors that drives healthy or unhealthy ageing. Too little is known about how contemporary dietary patterns and sedentary lifestyles will impact upon healthy ageing in future generations and this is a priority for future research. There is good evidence to support change to lifestyle (i.e. diet, nutrition and physical) activity in relation to maintaining or improving body composition, cognitive health and emotional intelligence, immune function and vascular health. Lifestyle change at any stage of life may extend healthy lifespan, although the impact of early changes appears to be greatest. © 2018 The British Dietetic Association Ltd.

  3. A holistic approach to chronic pain management that involves all stakeholders: change is needed.

    Science.gov (United States)

    Kress, Hans-Georg; Aldington, Dominic; Alon, Eli; Coaccioli, Stefano; Collett, Beverly; Coluzzi, Flaminia; Huygen, Frank; Jaksch, Wolfgang; Kalso, Eija; Kocot-Kępska, Magdalena; Mangas, Ana Cristina; Ferri, Cesar Margarit; Mavrocordatos, Philippe; Morlion, Bart; Müller-Schwefe, Gerhard; Nicolaou, Andrew; Hernández, Concepción Pérez; Sichère, Patrick

    2015-01-01

    Chronic pain affects a large proportion of the population, imposing significant individual distress and a considerable burden on society, yet treatment is not always instituted and/or adequate. Comprehensive multidisciplinary management based on the biopsychosocial model of pain has been shown to be clinically effective and cost-efficient, but is not widely available. A literature review of stakeholder groups revealed many reasons for this, including: i) many patients believe healthcare professionals lack relevant knowledge, and consultations are rushed, ii) general practitioners consider that pain management has a low priority and is under-resourced, iii) pain specialists cite non-adherence to evidence-based treatment, sub-optimal prescribing, and chronic pain not being regarded as a disease in its own right, iv) nurses', pharmacists' and physiotherapists' skills are not fully utilized, and v) psychological therapy is employed infrequently and often too late. Many of the issues relating to physicians could be addressed by improving medical training, both at undergraduate and postgraduate levels - for example, by making pain medicine a compulsory core subject of the undergraduate medical curriculum. This would improve physician/patient communication, increase the use of standardized pain assessment tools, and allow more patients to participate in treatment decisions. Patient care would also benefit from improved training for other multidisciplinary team members; for example, nurses could provide counseling and follow-up support, psychologists offer coping skills training, and physiotherapists have a greater role in rehabilitation. Equally important measures include the widespread adoption of a patient-centered approach, chronic pain being recognized as a disease in its own right, and the development of universal guidelines for managing chronic non-cancer pain. Perhaps the greatest barrier to improvement is lack of political will at both national and international

  4. A holistic approach to hydrocarbon source allocation in the subtidal sediments of Prince William Sound, Alaska, embayments

    International Nuclear Information System (INIS)

    Page, D.S.; Bence, A.E.; Burns, W.A.; Boehm, P.D.; Brown, J.S.; Douglas, G.S.

    2002-01-01

    The complex organic geochemistry record in the subtidal sediments of Prince William Sound, Alaska is a result of much industrial and human activity in the region. Recent oil spills and a regional background of natural petroleum hydrocarbons originating from active hydrocarbon systems in the northern Gulf of Alaska also contribute to the geochemical record. Pyrogenic and petrogenic polycyclic aromatic hydrocarbons (PAH) are introduced regularly to the subtidal sediments at sites of past and present human activities including villages, fish hatcheries, fish camps and recreational campsites as well as abandoned settlements, canneries, sawmills and mines. Hydrocarbon contributions are fingerprinted and quantified using a holistic approach where contributions from multiple sources is determined. The approach involves a good understanding of the history of the area to identify potential sources. It also involves extensive collection of representative samples and an accurate quantitative analysis of the source and sediment samples for PAH analytes and chemical biomarker compounds. Total organic carbon (TOC) does not work in restricted embayments because of a constrained least-square algorithm to determine hydrocarbon sources. It has been shown that sources contributing to the natural petrogenic background are present in Prince William Sound. In particular, pyrogenic hydrocarbons such as combustion products of diesel is significant where there was much human activity. In addition, petroleum produced from the Monterey Formation in California is present in Prince William Sound because in the past, oil and asphalt shipped from California was widely used for fuel. Low level residues of weathered Alaskan North Slope crude oil from the Exxon Valdez spill are also still present. 30 refs., 4 tabs., 2 figs

  5. The pitfalls of qualified moral veganism. A critique of Jan Deckers' holistic health approach to animal ethics.

    Science.gov (United States)

    Paez, Eze

    2017-10-01

    I critically examine Jan Deckers' position in Animal (De)liberation, where he defends two main views. The first is "qualified moral veganism": Most humans have a duty to abstain from consuming animal products, even if there are circumstances in which doing so is justified. The author argues, on the one hand, from a pan-sentientist view that attributes sentience to all elementary entities and their compounds. Thus, all living things (such as animals and plants) have a capacity for positive and negative experiences. On the other hand, he develops a consequentialist view that assigns moral agents the unconditional duty to promote their own "holistic health." This is partly constituted by the agent's "moral health," that is, her acting in a morally justified way. On Deckers' view, moral agents must care for the health of all living entities, give greater weight to the interests of organisms to which they are more closely biologically related, and respect the integrity of nature. Diets containing animal products have a very high negative health impact, because of how they affect the environment, human food security, and the well-being of nonhuman animals. In addition, even though plants are sentient, they are likely less so than animals, and their interests must be given less weight. Therefore, most humans should shift to a vegan diet. Deckers' second proposal is that a qualified ban on the consumption of animal products should be enacted. After discarding other alternative strategies, Deckers defends its feasibility relying on data obtained via a series of surveys. Though the argument partly succeeds in developing a coherent account accommodating the author's intuitions, I conclude that his ontological and normative frameworks remain too underdeveloped, his appeal to biological relatedness has implausible implications, and the methodology he uses in defence of his political position is problematic. © 2017 John Wiley & Sons, Ltd.

  6. The Microbiological Safety of Fresh Produce in Lebanon- A holistic “farm-to-fork chain” approach to evaluate food safety, compliance levels and underlying risk factors

    OpenAIRE

    Faour-Klingbeil, Dima

    2017-01-01

    The consumption of unsafe fresh vegetables has been linked to an increasing number of outbreaks of human infections. In Lebanon, although raw vegetables are major constituents of the national cuisine, studies on the safety of fresh produce are scant. This research employed a holistic approach to identify the different stages of the food chain that contribute to the microbiological risks on fresh produce and the spreading of hazards. A thorough analysis of the institutional and regulatory fram...

  7. Malaysia implements the integrated approach.

    Science.gov (United States)

    1977-01-01

    Malaysia has implemented an integrated approach in providing family planning services to eligible couples. In 1964 the government of Malaysia adopted a national family planning program, and implementation began in the urban areas and extended into the rural areas. Other agencies are involved in providing family planning services and information including the Federation of Family Planning Associations, the Ministry of Health, the National Family Planning Board, and the Federal Land Development Authority. The number of women practicing contraception has increased from 20,726 in 1967 to 533,646 by 1976. and other methods, 3.9%, respectively. There has been an increase in the percentage of acceptors between ages 15-29 from 56% in 1968 to 71.3% in 1975. The 2nd Malaysian national plan will use a multidisciplinary approach to the problem.

  8. Holistic-integrated analysis and evaluation of nuclear energy for sustainable energy supply; Ganzheitlich-integrierte Betrachtung der Kernenergie im Hinblick auf eine nachhaltige Energieversorgung

    Energy Technology Data Exchange (ETDEWEB)

    Wissel, Steffen [Stuttgart Univ. (Germany). Inst. fuer Energiewirtschaft und Rationelle Energieanwendung (IER)

    2012-11-01

    Germany has decided in 2011 nuclear phase-out by the end of 2022. The European Commission is still convinced of the safe use of nuclear energy as option for carbon reduction in the energy supply. In the European energy market the decisions of neighboring countries have an impact on the national energy systems. The contribution covers a holistic-integrated analysis based on technical, economic and ecologic aspects of nuclear energy for sustainable energy supply in comparison with other fossil and renewable systems.

  9. Exploration and Description of Faith-Based Health Resources: Findings Inform Advancing Holistic Health Care.

    Science.gov (United States)

    Dyess, Susan MacLeod

    2015-01-01

    It is important to use all holistic resource opportunities in communities, such as integrative healing centers, and mind-body-spirit approaches to health. These holistic approaches may be realized through nontraditional avenues, such as faith-based resources. This article reports on an exploratory study that describes faith-based resources supporting holistic health in a southeastern region of the United States. A working definition for "faith-based health resources" was "ecumenical and interfaith community-based, open-access health resources that include in mission for service a reference to faith." Excluded from the definition were institutional services from hospitals, focused social services from area agencies, and federally funded services.

  10. A Holistic Approach to Fishery Management: Evidence and Insights from a Central Mediterranean Case Study (Western Ionian Sea

    Directory of Open Access Journals (Sweden)

    Tommaso Russo

    2017-06-01

    Full Text Available The new Common Fisheries Policy (CFP is designed to represent an appropriate response to the uncertainties and challenges facing the fisheries sector. It also adopts a holistic approach to fisheries management, considering all factors driving fishers' behavior, and ultimately, the long-term maintenance of living resources. The most reliable way to pursue these aims could be represented by a change in the exploitation pattern, in order to guarantee the sustainability of fisheries without compromising their socioeconomic viability. In this paper, the demersal fisheries of the Ionian Sea [Geographic Sub-area (GSA 19] were analyzed with respect to their spatial, temporal, economic, and biological characteristics in terms of four key species for fisheries, namely European hake, red mullet, giant red shrimp, and deep-water rose shrimp. Specifically, (1 a quantitative procedure was applied to break down the whole system (including small-scale fleet components into a series of fishing grounds using input data about fishing efforts; (2 the different fleet segments were defined as a combination of main gear and fishing grounds; (3 the effort and production by fleet segment were derived according to biological samplings of commercial data (Data Collection Framework for the collection and management of fisheries data, DCF, information on localization of nursery and spawning grounds, and expert knowledge; and (4 all this information was used to feed a bioeconomic modeling tool (BEMTOOL, and to explore alternative exploitation patterns. A series of scenarios including the status quo were defined, starting from the actual management approach based on temporal fishing closure. The results showed that significant improvements in the exploitation pattern could be achieved by setting up spatial and/or temporal gear-specific bans of the fishing activity. More specifically, scenarios based on a 3-month fishing ban for trawlers are expected to provide high rebuilding

  11. Integrative approaches to childhood constipation and encopresis.

    Science.gov (United States)

    Culbert, Timothy P; Banez, Gerard A

    2007-12-01

    Constipation and encopresis (fecal soiling) are common childhood disorders that may lead to significant functional impairment. The etiology and course of constipation and encopresis are increasingly conceptualized from a broad biopsychosocial perspective, and therefore a holistic approach to assessment and treatment is indicated. Many children experience symptoms of chronic constipation and/or encopresis that are only partially responsive to conventional medical therapy. Complementary/alternative therapies can often help in the treatment of constipation/encopresis and are well accepted by patients and families.

  12. The Place and Approach of Outdoor Learning within a Holistic Curricular Agenda: Development of Singaporean Outdoor Education Practice

    Science.gov (United States)

    Atencio, Matthew; Tan, Yuen Sze Michelle; Ho, Susanna; Ching, Chew Ting

    2015-01-01

    This paper details the potential contribution of outdoor education (OE) in Singaporean education given the recent raft of national curricular reforms aimed at fostering holistic and exploratory learning opportunities. In this context, we contend that increasing recognition of the value of OE, both internationally and locally, heralds specific…

  13. Integrated approaches to perceptual learning.

    Science.gov (United States)

    Jacobs, Robert A

    2010-04-01

    New technologies and new ways of thinking have recently led to rapid expansions in the study of perceptual learning. We describe three themes shared by many of the nine articles included in this topic on Integrated Approaches to Perceptual Learning. First, perceptual learning cannot be studied on its own because it is closely linked to other aspects of cognition, such as attention, working memory, decision making, and conceptual knowledge. Second, perceptual learning is sensitive to both the stimulus properties of the environment in which an observer exists and to the properties of the tasks that the observer needs to perform. Moreover, the environmental and task properties can be characterized through their statistical regularities. Finally, the study of perceptual learning has important implications for society, including implications for science education and medical rehabilitation. Contributed articles relevant to each theme are summarized. Copyright © 2010 Cognitive Science Society, Inc.

  14. Infectious diseases in oyster aquaculture require a new integrated approach.

    Science.gov (United States)

    Pernet, Fabrice; Lupo, Coralie; Bacher, Cédric; Whittington, Richard J

    2016-03-05

    Emerging diseases pose a recurrent threat to bivalve aquaculture. Recently, massive mortality events in the Pacific oyster Crassostrea gigas associated with the detection of a microvariant of the ostreid herpesvirus 1 (OsHV-1µVar) have been reported in Europe, Australia and New Zealand. Although the spread of disease is often viewed as a governance failure, we suggest that the development of protective measures for bivalve farming is presently held back by the lack of key scientific knowledge. In this paper, we explore the case for an integrated approach to study the management of bivalve disease, using OsHV-1 as a case study. Reconsidering the key issues by incorporating multidisciplinary science could provide a holistic understanding of OsHV-1 and increase the benefit of research to policymakers. © 2016 The Author(s).

  15. The HAPPY study (Holistic Approach to Pregnancy and the first Postpartum Year): design of a large prospective cohort study.

    Science.gov (United States)

    Truijens, Sophie E M; Meems, Margreet; Kuppens, Simone M I; Broeren, Maarten A C; Nabbe, Karin C A M; Wijnen, Hennie A; Oei, S Guid; van Son, Maarten J M; Pop, Victor J M

    2014-09-08

    The HAPPY study is a large prospective longitudinal cohort study in which pregnant women (N ≈ 2,500) are followed during the entire pregnancy and the whole first year postpartum. The study collects a substantial amount of psychological and physiological data investigating all kinds of determinants that might interfere with general well-being during pregnancy and postpartum, with special attention to the effect of maternal mood, pregnancy-related somatic symptoms (including nausea and vomiting (NVP) and carpal tunnel syndrome (CTS) symptoms), thyroid function, and human chorionic gonadotropin (HCG) on pregnancy outcome of mother and foetus. During pregnancy, participants receive questionnaires at 12, 22 and 32 weeks of gestation. Apart from a previous obstetric history, demographic features, distress symptoms, and pregnancy-related somatic symptoms are assessed. Furthermore, obstetrical data of the obstetric record form and ultrasound data are collected during pregnancy. At 12 and 30 weeks, thyroid function is assessed by blood analysis of thyroid stimulating hormone (TSH), free thyroxine (FT4) and thyroid peroxidase antibodies (TPO-Ab), as well as HCG. Also, depression is assessed with special focus on the two key symptoms: depressed mood and anhedonia. After childbirth, cord blood, neonatal heel screening results and all obstetrical data with regard to start of labour, mode of delivery and complications are collected. Moreover, mothers receive questionnaires at one week, six weeks, four, eight, and twelve months postpartum, to investigate recovery after pregnancy and delivery, including postpartum mood changes, emotional distress, feeding and development of the newborn. The key strength of this large prospective cohort study is the holistic (multifactorial) approach on perinatal well-being combined with a longitudinal design with measurements during all trimesters of pregnancy and the whole first year postpartum, taking into account two physiological possible

  16. DOE systems approach and integration

    International Nuclear Information System (INIS)

    Logan, J.A.

    1987-01-01

    Six sites are now disposing of most of DOE's currently generated waste. These are: Hanford, Idaho National Engineering Laboratory, Los Alamos National Laboratory, the Nevada Test Site, Oak Ridge, and Savannah River. Within DOE, experience with disposal of solid LLW has been that arid site disposal facilities (first four) appear to have performed well, while humid site disposal facilities (last two) have experienced some waste migration. DOE's intent, of course, is to operate all its waste disposal facilities so that public health and safety are not adversely affected. To ensure that this continues to be the case, activities are underway to increase use of waste form stabilization and engineered barriers where appropriate. For the sake of overall economy, these measures are to be applied as and where needed, through use of the systems approach. In this paper the author discusses two topics: the system approach, which DOE has decided to use for resolving waste disposal problems in the management of DOE's low-level wastes; and DOE's intended integration of activities underway at the waste management systems throughout DOE facilities. 2 figures

  17. Risk assessment concept in the new approach directives and its integration in the Enterprise Risk Management (ERM

    Directory of Open Access Journals (Sweden)

    Đapić Mirko

    2012-03-01

    Full Text Available In the nineties years of the previous century, the European Union achieved, through introducing the New and Global Approach to technical harmonization and standardization, a significant improvement in the approach to conformity assessment of products, by integrating the requirements for technical products safety into the process of its designing. This was achieved by preventive analyzing and quantifying of risk levels in the design process with the objective of determining the scope of the needed safety systems. On the other hand, we have witnessed a rapid development and implementation of holistic approaches to risks management in enterprises, unified in the modern business practice by the name of Enterprise Risk Management (ERM. Going along that line, the paper presents, through the basis of the EU New and Global Approach, the concept of risk assessment in the New Approach directives (Machinery, Lifts, ATEX, etc and provides the concept of its integration into the holistic approach of risks management in enterprises, such as ERM.

  18. Clinical Holistic Medicine: Holistic Treatment of Children

    Directory of Open Access Journals (Sweden)

    Søren Ventegodt

    2004-01-01

    Full Text Available We believe a holistic approach to problems in childhood and adolescence will benefit the child, adolescent, and the whole family. As a rule, children have far less to say in the family than their parents. Therefore, it is the parents who set the agenda and decide how things are done at home and in relation to the child. Most often, it is also the parents who have a problem when the child is not thriving. The child thus acts as the thermometer of the family. When children are not feeling well or are sick, the parents are not doing well either. Most problems arising from dysfunctional patterns are almost impossible for the parents to solve on their own, but with help and support from the holistically oriented physician, we believe that many problems can be discovered and solved. Not only can health problems be addressed, but also problems of poor thriving in the family in general. With the physician in the role of a coach, the family can be provided with relevant exercises that will change the patterns of dysfunction. Consciousness-based medicine also seems to be efficient with children and adolescents, who are much more sensitive to the psychosocial dimensions than adults. Five needs seem to be essential for the thriving and health of the child: attention, respect, love, acceptance (touch, and acknowledgment. The physician should be able to see if the child lacks fulfillment in one or more of these needs, and he can then demonstrate to the parents how these needs should be handled. This should be followed by simple instructions and exercises for the parents in the spirit of coaching. This approach is especially relevant when the child is chronically ill.

  19. Biomedicine or Holistic Medicine for Treating Mentally Ill Patients? A Philosophical and Economical Analysis

    Directory of Open Access Journals (Sweden)

    Søren Ventegodt

    2007-01-01

    Full Text Available Today we have two scientific medical traditions, two schools or treatment systems: holistic medicine and biomedicine. The two traditions are based on two very different philosophical positions: subjectivistic and objectivistic. The philosopher Buber taught us that you can say I-Thou or I-It, holding the other person as a subject or an object. These two fundamentally different attitudes seem to characterize the difference in world view and patient approach in the two schools, one coming from psychoanalysis and the old, holistic tradition of Hippocratic medicine. Holistic medicine during the last decade has developed its philosophical positions and is today an independent, medical system seemingly capable of curing mentally ill patients at the cost of a few thousand Euros with no side effects and with lasting value for the patient. The problem is that very few studies have tested the effect of holistic medicine on mentally ill patients. Another problem is that the effect of holistic medicine must be documented in a way that respects this school's philosophical integrity, allowing for subjective assessment of patient benefit and using the patient as his/her own control, as placebo control cannot be used in placebo-only treatment. As the existing data are strongly in favor of using holistic medicine, which seems to be safer, more efficient, and cheaper, it is recommended that clinical holistic medicine also be used as treatment for mental illness. More research and funding is needed to develop scientific holistic medicine.

  20. Biomedicine or holistic medicine for treating mentally ill patients? A philosophical and economical analysis.

    Science.gov (United States)

    Ventegodt, Søren; Kandel, Isack; Merrick, Joav

    2007-12-18

    Today we have two scientific medical traditions, two schools or treatment systems: holistic medicine and biomedicine. The two traditions are based on two very different philosophical positions: subjectivistic and objectivistic. The philosopher Buber taught us that you can say I-Thou or I-It, holding the other person as a subject or an object. These two fundamentally different attitudes seem to characterize the difference in world view and patient approach in the two schools, one coming from psychoanalysis and the old, holistic tradition of Hippocratic medicine. Holistic medicine during the last decade has developed its philosophical positions and is today an independent, medical system seemingly capable of curing mentally ill patients at the cost of a few thousand Euros with no side effects and with lasting value for the patient. The problem is that very few studies have tested the effect of holistic medicine on mentally ill patients. Another problem is that the effect of holistic medicine must be documented in a way that respects this school's philosophical integrity, allowing for subjective assessment of patient benefit and using the patient as his/her own control, as placebo control cannot be used in placebo-only treatment. As the existing data are strongly in favor of using holistic medicine, which seems to be safer, more efficient, and cheaper, it is recommended that clinical holistic medicine also be used as treatment for mental illness. More research and funding is needed to develop scientific holistic medicine.

  1. A novel integrated renewable energy system modelling approach, allowing fast FPGA controller prototyping

    DEFF Research Database (Denmark)

    Teodorescu, Remus; Ruiz, Alberto Parera; Cirstea, Marcian

    2008-01-01

    The paper describes a new holistic approach to the modeling of integrated renewable energy systems. The method is using the DK5 modeling/design environment from Celoxica and is based on the new Handel-C programming language. The goal of the work carried out was to achieve a combined model...... containing a Xilinx Spartan II FPGA and was successfully experimentally tested. This approach enables the design and fast hardware implementation of efficient controllers for Distributed Energy Resource (DER) hybrid systems....... of a photovoltaic energy system and a wind power system, which would allow an optimized holistic digital control system design, followed by rapid prototyping of the controller into a single Field Programmable Gate Array (FPGA). Initially, the system was simulated using Matlab / Simulink, to create a reference...

  2. Social Media for the Promotion of Holistic Self-Participatory Care: An Evidence Based Approach. Contribution of the IMIA Social Media Working Group.

    Science.gov (United States)

    Miron-Shatz, T; Hansen, M M; Grajales, F J; Martin-Sanchez, F; Bamidis, P D

    2013-01-01

    As health information is becoming increasingly accessible, social media offers ample opportunities to track, be informed, share and promote health. These authors explore how social media and holistic care may work together; more specifically however, our objective is to document, from different perspectives, how social networks have impacted, supported and helped sustain holistic self-participatory care. A literature review was performed to investigate the use of social media for promoting health in general and complementary alternative care. We also explore a case study of an intervention for improving the health of Greek senior citizens through digital and other means. The Health Belief Model provides a framework for assessing the benefits of social media interventions in promoting comprehensive participatory self-care. Some interventions are particularly effective when integrating social media with real-world encounters. Yet not all social media tools are evidence-based and efficacious. Interestingly, social media is also used to elicit patient ratings of treatments (e.g., for depression), often demonstrating the effectiveness of complementary treatments, such as yoga and mindfulness meditation. To facilitate the use of social media for the promotion of complementary alternative medicine through self-quantification, social connectedness and sharing of experiences, exploration of concrete and abstract ideas are presented here within. The main mechanisms by which social support may help improve health - emotional support, an ability to share experiences, and non-hierarchal roles, emphasizing reciprocity in giving and receiving support - are integral to social media and provide great hope for its effective use.

  3. Issues in holistic system design

    DEFF Research Database (Denmark)

    Lawall, Julia L.; Probst, Christian W.; Schultz, Ulrik Pagh

    2006-01-01

    The coordination of layers in computer and software systems is one of the main challenges in designing such systems today. In this paper we consider Holistic System Design as a way of integrating requirements and facilities of different system layers. We also discuss some of the challenges...

  4. GlobaliFusion, The First Worldwide, Holistic, Information & Communication Technologies (ICT) and Big Data Aggregation Approach to Social Media Marketing

    OpenAIRE

    Greg Sand; Leonidas Tsitouras; George Dimitrakopoulos; Vassilis Chatzigiannakis

    2015-01-01

    The internet and Social Media have been playing a vital role in almost everyone’s communication and interactions. The same holds true for a company’s two-way communication with its consumers. This tremendous flow of information can drastically increase any company’s exposure to its consumers and shoppers. Consequently, it can decisively affect consumers’ opinion about products and services. Molloy College in Rockville Centre, New York is the home of GiF, the first worldwide, holistic ICT-base...

  5. From integrated control to integrated farming, an experimental approach

    NARCIS (Netherlands)

    Vereijken, P.H.

    1989-01-01

    Integrated control or integrated pest management (IPM), as envisaged originally, is not being practised to any large extent in arable farming, notwithstanding considerable research efforts. The reasons for this are discussed. A more basic approach called integrated farming is suggested. Preliminary

  6. Integral or integrated marketing

    Directory of Open Access Journals (Sweden)

    Davčik Nebojša

    2006-01-01

    Full Text Available Marketing theorists and experts try to develop business efficient organization and to get marketing performance at higher, business integrated level since its earliest beginnings. The core issue in this paperwork is the dialectic and practical approach dilemma should we develop integrated or integral marketing approach in the organization. The presented company cases as well as dialectic and functional explanations of this dilemma clearly shows that integrated marketing is narrower approach than integral marketing if we take as focal point new, unique and completed entity. In the integration the essence is in getting different parts together, which do not have to make necessary the new entity. The key elements in the definition of the integral marketing are necessity and holistic, e.g. necessity to develop new, holistic entity.

  7. Data integration approaches using ETL

    Directory of Open Access Journals (Sweden)

    Alexandra Maria Ioana FLOREA

    2016-01-01

    Full Text Available Traditional data warehouses and ETL tools have been slowly pushed to expand their limits as big data has become a more and more prominent actor on the analytics stage. This paper analyzes and compares the features of Pentaho Data Integration and Oracle Data Integrator, two of the main data integration platforms. Such tools are relevant in the context of the evolution of the analytics field, which is expanding from classical business intelligence activities to the use and analysis of big data.

  8. A Holistic Approach to Enhance the Use of Neglected and Underutilized Species: The Case of Andean Grains in Bolivia and Peru

    Directory of Open Access Journals (Sweden)

    Stefano Padulosi

    2014-03-01

    Full Text Available The IFAD-NUS project, implemented over the course of a decade in two phases, represents the first UN-supported global effort on neglected and underutilized species (NUS. This initiative, deployed and tested a holistic and innovative value chain framework using multi-stakeholder, participatory, inter-disciplinary, pro-poor gender- and nutrition-sensitive approaches. The project has been linking aspects often dealt with separately by R&D, such as genetic diversity, selection, cultivation, harvest, value addition, marketing, and final use, with the goal to contribute to conservation, better incomes, and improved nutrition and strengthened livelihood resilience. The project contributed to the greater conservation of Andean grains and their associated indigenous knowledge, through promoting wider use of their diversity by value chain actors, adoption of best cultivation practices, development of improved varieties, dissemination of high quality seed, and capacity development. Reduced drudgery in harvest and postharvest operations, and increased food safety were achieved through technological innovations. Development of innovative food products and inclusion of Andean grains in school meal programs is projected to have had a positive nutrition outcome for targeted communities. Increased income was recorded for all value chain actors, along with strengthened networking skills and self-reliance in marketing. The holistic approach taken in this study is advocated as an effective strategy to enhance the use of other neglected and underutilized species for conservation and livelihood benefits.

  9. Improving Electronic Resources through Holistic Budgeting

    Science.gov (United States)

    Kusik, James P.; Vargas, Mark A.

    2009-01-01

    To establish a more direct link between its collections and the educational goals of Saint Xavier University, the Byrne Memorial Library has adopted a "holistic" approach to collection development. This article examines how traditional budget practices influenced the library's selection of resources and describes how holistic collection…

  10. A Holistic Approach for Addressing the Issue of Effective Technology Transfer in the Frame of Climate Change

    Directory of Open Access Journals (Sweden)

    Charikleia Karakosta

    2016-06-01

    Full Text Available Climate change policy and sustainable development issues and goals are closely intertwined. Recognizing the dual relationship between sustainable development and climate change points to a need for the exploration of actions that jointly address sustainable development and climate change. Technology transfer is considered an issue with growing interest worldwide and has been recognized as the key in supporting countries to achieve sustainable development, while addressing climate change challenges. This study presents an integrated decision support methodological framework for the formulation and evaluation of activities to promote technology transfer, as well as the provision of clear recommendations and strategies for framing specific policy in the context of climate change. The philosophy of the proposed approach, under the name: assess-identify-define (AID, consists of three components, where each one focuses on a particular problem. The methodology is integrated using appropriate tools in the information decision support system for effective technology transfer (DSS-ΕTT. The pilot application of the proposed methodology, in five representative developing countries, provided the possibility to evaluate the characteristics of the adopted methodology in terms of completeness, usability, extensionality, as well as analysis of results reliability.

  11. Insights into invasion and restoration ecology: Time to collaborate towards a holistic approach to tackle biological invasions

    Directory of Open Access Journals (Sweden)

    Mirijam Gaertner

    2012-02-01

    Full Text Available The aim of our study is to provide an integrated framework for the management of alien plant invasions, combining insights and experiences from the fields of invasion and restoration ecology to enable more effective management of invasive species. To determine linkages between the scientific outputs of the two disciplines we used an existing data base on restoration studies between 2000 and 2008 and did a bibliometric analysis. We identified the type of restoration applied, determined by the aim of the study, and conducted a content analysis on 208 selected studies with a link to biological invasions (invasion-restoration studies. We found a total of 1075 articles on ecosystem restoration, with only eight percent of the studiesthe main objective to control alien invasions. The content analysis of 208 invasion-restoration studies showed that the majority of the studies focused on causes of degradation other than alien invasions. If invaders were referred to as the main driver of degradation, the prevalent cause for degradation was invaders outcompeting and replacing native species. Mechanical control of alien plant invasions was by far the most common control method used. Measures that went beyond the removal of alien plants were implemented in sixty-five percent of the studies.Although invasion control was not as common as other types of restoration, a closer look at the sub-group of invasion-restoration studies shows a clear link between restoration and invasion ecology. Concerns, as identified in the literature review, are firstly that restoration activities mostly focus on controlling the invader while other underlying causes for degradation are neglected, and secondly that the current approach of dealing with alien invasions lacks a combination of theoretical and practical aspects. We suggest that closer collaboration between invasion and restoration ecologists can help to improve the management of alien plant invasions. We conclude with a

  12. Use of an holistic approach for effective adoption of User-Centred-Design techniques in diabetes disease management: Experiences in user need elicitation.

    Science.gov (United States)

    Fico, Giuseppe; Arredondo, Maria Teresa

    2015-01-01

    One of the most important challenges of designing eHealth tools for Chronic Disease Management is to understand how transforming cutting-edge innovations in something that can impact the current clinical practice and improve the performance of the health care systems. The adoption of User Centered Design techniques is fundamental in order to integrate these systems in an effective and successful way. The work presented in this paper describe the methodologies used in the context of two multidisciplinary research projects, METABO and MOSAIC. The adoption of the methodologies have been driven by the CeHRes Roamap, a holistic framework that support participatory development of eHealth. The work reported in this paper describes the results of the first two (out of the five) phases in eliciting user needs.

  13. A multimetric approach for predicting the ecological integrity of New Zealand streams

    Directory of Open Access Journals (Sweden)

    Clapcott J.E.

    2014-01-01

    Full Text Available Integrating multiple measures of stream health into a combined metric can provide a holistic assessment of the ecological integrity of a stream. The aim of this study was to develop a multimetric index (MMI of stream integrity based on predictive modelling of national data sets of water quality, macroinvertebrates, fish and ecosystem process metrics. We used a boosted regression tree approach to calculate an observed/expected score for each metric prior to combining metrics in a MMI based on data availability and the strength of predictive models. The resulting MMI provides a geographically meaningful prediction of the ecological integrity of rivers in New Zealand, but identifies limitations in data and approach, providing focus for ongoing research.

  14. Achieving a holistic perspective in stroke rehabilitation

    DEFF Research Database (Denmark)

    Kristensen, Hanne Kaae; Lund, Hans; Jones, Dorrie

    2015-01-01

    Background/Aims: Holistic, multidisciplinary rehabilitation is often the most appropriate for stroke patients. The World Health Organization’s International Classification of Functioning, Disability and Health (ICF) provides a comprehensive conceptual framework and systematic terminology used...... to a holistic approach in stroke rehabilitation, including an understanding of functioning and the ability to participate in everyday life. Using this approach to rehabilitation, disability is not only perceived as a consequence of stroke but also in the context of the individual person, where interactions...... the holistic approach....

  15. Self-care essential extras: an integration of holistic nursing, functional medicine, and health coaching to promote therapeutic lifestyle change and decrease chronic disease.

    Science.gov (United States)

    Scattergood, Donna M

    2010-01-01

    The Essential Vitality Program blends holistic nursing, functional medicine, and health coaching to promote lifestyle changes that modify risk factors of costly chronic disease. Karl is a client who experienced enhanced vitality, decreased chronic pain and medications use, and improved meaningful functioning, by partnering with a holistic nurse coach.

  16. Systems healthcare: a holistic paradigm for tomorrow.

    Science.gov (United States)

    Fiandaca, Massimo S; Mapstone, Mark; Connors, Elenora; Jacobson, Mireille; Monuki, Edwin S; Malik, Shaista; Macciardi, Fabio; Federoff, Howard J

    2017-12-19

    Systems healthcare is a holistic approach to health premised on systems biology and medicine. The approach integrates data from molecules, cells, organs, the individual, families, communities, and the natural and man-made environment. Both extrinsic and intrinsic influences constantly challenge the biological networks associated with wellness. Such influences may dysregulate networks and allow pathobiology to evolve, resulting in early clinical presentation that requires astute assessment and timely intervention for successful mitigation. Herein, we describe the components of relevant biological systems and the nature of progression from at-risk to manifest disease. We illustrate the systems approach by examining two relevant clinical examples: Alzheimer's and cardiovascular diseases. The implications of systems healthcare management are examined through the lens of economics, ethics, policy and the law. Finally, we propose the need to develop new educational paradigms to enhance the training of the health professional in an era of systems medicine.

  17. A transnational and holistic breeding approach is needed for sustainable wheat production in the Baltic Sea region.

    Science.gov (United States)

    Chawade, Aakash; Armoniené, Rita; Berg, Gunilla; Brazauskas, Gintaras; Frostgård, Gunilla; Geleta, Mulatu; Gorash, Andrii; Henriksson, Tina; Himanen, Kristiina; Ingver, Anne; Johansson, Eva; Jørgensen, Lise Nistrup; Koppel, Mati; Koppel, Reine; Makela, Pirjo; Ortiz, Rodomiro; Podyma, Wieslaw; Roitsch, Thomas; Ronis, Antanas; Svensson, Jan T; Vallenback, Pernilla; Weih, Martin

    2018-03-14

    The Baltic Sea is one of the largest brackish water bodies in the world. Eutrophication is a major concern in the Baltic Sea due to the leakage of nutrients to the sea with agriculture being the primary source. Wheat (Triticum aestivum L.) is the most widely grown crop in the countries surrounding the Baltic Sea and thus promoting sustainable agriculture practices for wheat cultivation will have a major impact on reducing pollution in the Baltic Sea. This approach requires identifying and addressing key challenges for sustainable wheat production in the region. Implementing new technologies for climate-friendly breeding and digital farming across all surrounding countries should promote sustainable intensification of agriculture in the region. In this review, we highlight major challenges for wheat cultivation in the Baltic Sea region and discuss various solutions integrating transnational collaboration for pre-breeding and technology sharing to accelerate development of low input wheat cultivars with improved host plant resistance to pathogen and enhanced adaptability to the changing climate. © 2018 The Authors. Physiologia Plantarum published by John Wiley & Sons Ltd on behalf of Scandinavian Plant Physiology Society.

  18. INTEGRATED EXPERIENCE APPROACH TO LEARNING.

    Science.gov (United States)

    POSTLETHWAIT, S.N.; AND OTHERS

    THE USE OF AUDIOTUTORIAL TECHNIQUES FOR TEACHING INTRODUCTORY COLLEGE BOTANY IS DESCRIBED. SPECIFIC PRACTICES USED AT PURDUE UNIVERSITY TO ILLUSTRATE DIFFERENT FACETS OF THE APPROACH ARE ANALYZED. INCLUDED ARE INDEPENDENT STUDY SESSIONS, SMALL ASSEMBLY SESSIONS, GENERAL ASSEMBLY SESSIONS, AND HOME STUDY SESSIONS. ILLUSTRATIONS AND SPECIFICATIONS…

  19. Integrative approaches to computational biomedicine

    Science.gov (United States)

    Coveney, Peter V.; Diaz-Zuccarini, Vanessa; Graf, Norbert; Hunter, Peter; Kohl, Peter; Tegner, Jesper; Viceconti, Marco

    2013-01-01

    The new discipline of computational biomedicine is concerned with the application of computer-based techniques and particularly modelling and simulation to human health. Since 2007, this discipline has been synonymous, in Europe, with the name given to the European Union's ambitious investment in integrating these techniques with the eventual aim of modelling the human body as a whole: the virtual physiological human. This programme and its successors are expected, over the next decades, to transform the study and practice of healthcare, moving it towards the priorities known as ‘4P's’: predictive, preventative, personalized and participatory medicine.

  20. Integrative medicine approach to chronic pain.

    Science.gov (United States)

    Teets, Raymond Y; Dahmer, Stephen; Scott, Emilie

    2010-06-01

    Chronic pain can be a frustrating condition for patient and clinician. The integrative medicine approach to pain can offer hope, adding safe complementary and alternative medical (CAM) therapies to mitigate pain and suffering. Such CAM therapies include nutrition, supplements and herbs, manual medicine, acupuncture, yoga, and mind-body approaches. The evidence is heterogeneous regarding these approaches, but some evidence suggests efficacy and confirms safety. The integrative medicine approach can be beneficial in a patient with chronic pain. Copyright 2010 Elsevier Inc. All rights reserved.

  1. Statistical inference an integrated approach

    CERN Document Server

    Migon, Helio S; Louzada, Francisco

    2014-01-01

    Introduction Information The concept of probability Assessing subjective probabilities An example Linear algebra and probability Notation Outline of the bookElements of Inference Common statistical modelsLikelihood-based functions Bayes theorem Exchangeability Sufficiency and exponential family Parameter elimination Prior Distribution Entirely subjective specification Specification through functional forms Conjugacy with the exponential family Non-informative priors Hierarchical priors Estimation Introduction to decision theoryBayesian point estimation Classical point estimation Empirical Bayes estimation Comparison of estimators Interval estimation Estimation in the Normal model Approximating Methods The general problem of inference Optimization techniquesAsymptotic theory Other analytical approximations Numerical integration methods Simulation methods Hypothesis Testing Introduction Classical hypothesis testingBayesian hypothesis testing Hypothesis testing and confidence intervalsAsymptotic tests Prediction...

  2. Functional integral approach to classical statistical dynamics

    International Nuclear Information System (INIS)

    Jensen, R.V.

    1980-04-01

    A functional integral method is developed for the statistical solution of nonlinear stochastic differential equations which arise in classical dynamics. The functional integral approach provides a very natural and elegant derivation of the statistical dynamical equations that have been derived using the operator formalism of Martin, Siggia, and Rose

  3. Sexual and reproductive health and rights: integration as a holistic and rights-based response to HIV/AIDS.

    Science.gov (United States)

    Barroso, Carmen; Sippel, Serra

    2011-11-01

    For decades, donors, governments, and civil society have recognized the importance of sexual and reproductive health and rights (SRHR) in efforts to alleviate poverty and advance gender equality and women's rights. More recently, in the battle against HIV/AIDS--and given the unique challenges the pandemic presents for health and development--the global community has acknowledged the benefits of synergizing sexual and reproductive health and HIV/AIDS interventions. However, the United States has been slow to incorporate lessons learned from the international experience when it comes to integrating HIV/AIDS, SRHR, and gender equality in the fight against HIV/AIDS. This article highlights the importance of SRHR and lessons learned from SRHR-HIV integration to inform U.S. domestic and global AIDS strategies and interventions. Copyright © 2011 Jacobs Institute of Women's Health. Published by Elsevier Inc. All rights reserved.

  4. On the holistic approach in cellular and cancer biology: nonlinearity, complexity, and quasi-determinism of the dynamic cellular network.

    Science.gov (United States)

    Waliszewski, P; Molski, M; Konarski, J

    1998-06-01

    A keystone of the molecular reductionist approach to cellular biology is a specific deductive strategy relating genotype to phenotype-two distinct categories. This relationship is based on the assumption that the intermediary cellular network of actively transcribed genes and their regulatory elements is deterministic (i.e., a link between expression of a gene and a phenotypic trait can always be identified, and evolution of the network in time is predetermined). However, experimental data suggest that the relationship between genotype and phenotype is nonbijective (i.e., a gene can contribute to the emergence of more than just one phenotypic trait or a phenotypic trait can be determined by expression of several genes). This implies nonlinearity (i.e., lack of the proportional relationship between input and the outcome), complexity (i.e. emergence of the hierarchical network of multiple cross-interacting elements that is sensitive to initial conditions, possesses multiple equilibria, organizes spontaneously into different morphological patterns, and is controlled in dispersed rather than centralized manner), and quasi-determinism (i.e., coexistence of deterministic and nondeterministic events) of the network. Nonlinearity within the space of the cellular molecular events underlies the existence of a fractal structure within a number of metabolic processes, and patterns of tissue growth, which is measured experimentally as a fractal dimension. Because of its complexity, the same phenotype can be associated with a number of alternative sequences of cellular events. Moreover, the primary cause initiating phenotypic evolution of cells such as malignant transformation can be favored probabilistically, but not identified unequivocally. Thermodynamic fluctuations of energy rather than gene mutations, the material traits of the fluctuations alter both the molecular and informational structure of the network. Then, the interplay between deterministic chaos, complexity, self

  5. Sustainable Use Of Macro-Algae For Biogas Production In Latvian Conditions: A Preliminary Study Through An Integrated Mca And Lca Approach

    Directory of Open Access Journals (Sweden)

    Pastare Laura

    2014-12-01

    Full Text Available The study focuses on sustainability evaluation of an algae-based energy system in Latvia with a holistic and integrated approach of multi-criteria analysis combined with life cycle assessment (including a practical side - biogas yield experiments of locally available algae.

  6. A holistic perspective on corporate sustainability drivers

    NARCIS (Netherlands)

    Lozano, R.

    2013-01-01

    Since company boards are increasingly discussing 'sustainability', it becomes necessary to examine the nature of sustainability drivers. Most approaches to corporate sustainability drivers have focused either on internal or external drivers. This paper is aimed at providing a more holistic

  7. A holistic perspective on corporate sustainability drivers

    NARCIS (Netherlands)

    Lozano, Rodrigo|info:eu-repo/dai/nl/36412380X

    2015-01-01

    Since company boards are increasingly discussing 'sustainability', it becomes necessary to examine the nature of sustainability drivers. Most approaches to corporate sustainability drivers have focused either on internal or external drivers. This paper is aimed at providing a more holistic

  8. A legacy building model for holistic nursing.

    Science.gov (United States)

    Lange, Bernadette; Zahourek, Rothlyn P; Mariano, Carla

    2014-06-01

    This pilot project was an effort to record the historical roots, development, and legacy of holistic nursing through the visionary spirit of four older American Holistic Nurses Association (AHNA) members. The aim was twofold: (a) to capture the holistic nursing career experiences of elder AHNA members and (b) to begin to create a Legacy Building Model for Holistic Nursing. The narratives will help initiate an ongoing, systematic method for the collection of historical data and serve as a perpetual archive of knowledge and inspiration for present and future holistic nurses. An aesthetic inquiry approach was used to conduct in-depth interviews with four older AHNA members who have made significant contributions to holistic nursing. The narratives provide a rich description of their personal and professional evolution as holistic nurses. The narratives are presented in an aesthetic format of the art forms of snapshot, pastiche, and collage rather than traditional presentations of research findings. A synopsis of the narratives is a dialogue between the three authors and provides insight for how a Legacy Model can guide our future. Considerations for practice, education, and research are discussed based on the words of wisdom from the four older holistic nurses.

  9. Toward an Integrated Psychological Approach - Phase II

    International Development Research Centre (IDRC) Digital Library (Canada)

    Trauma, Development and Peacebuilding : Toward an Integrated Psychological Approach - Phase II. Over the past decade, the peace, conflict and development community has begun to question the value of medicalized approaches such as post-traumatic stress disorder (PTSD) in dealing with aftermath of political violence ...

  10. The Holistic Health Movement.

    Science.gov (United States)

    Gross, Stanley J.

    1980-01-01

    Provides a conceptual framework for understanding the holistic health field so counselors may consider its implications in addressing a new service area. Holistic health has unique emphases on positive wellness, environmental concerns, self-responsibility, and such practices as meditation, fitness, nourishment, vitality, and spirituality. (Author)

  11. Toward Integrated Resource Management: Lessons About the EcosystemApproach from the Laurentian Great Lakes

    Science.gov (United States)

    MACKENZIE

    1997-03-01

    / The ecosystem approach is an innovative tool for integratedresource management. Its goal is to restore, enhance, and protect ecosystemintegrity through a holistic and integrated mode of planning. Under thisapproach, the ecosystem itself becomes the unit of analysis and organizingprinciple for environmental management. Utilizing the ecosystem approachchallenges the prevailing structure and function of contemporary resourcemanagement agencies. This paper explores a number of important policy andmanagement issues in the context of a ten-year initiative to remediate theLaurentian Great Lakes using the ecosystem approach. The lessons gleaned fromthe Great Lakes experience are relevant to other areas in North America andabroad where resource management responsibilities are held by multiple andsometimes overlapping jurisdictions.KEY WORDS: Integrated resource management; Ecosystem approach; Watershedmanagement; Great Lakes

  12. Integrated Care in Prostate Cancer (ICARE-P): Nonrandomized Controlled Feasibility Study of Online Holistic Needs Assessment, Linking the Patient and the Health Care Team.

    Science.gov (United States)

    Nanton, Veronica; Appleton, Rebecca; Dale, Jeremy; Roscoe, Julia; Hamborg, Thomas; Ahmedzai, Sam H; Arvanitis, Theodoros N; Badger, Douglas; James, Nicholas; Mendelsohn, Richard; Khan, Omar; Parashar, Deepak; Patel, Prashant

    2017-07-28

    The potential of technology to aid integration of care delivery systems is being explored in a range of contexts across a variety of conditions in the United Kingdom. Prostate cancer is the most common cancer in UK men. With a 10-year survival rate of 84%, there is a need to explore innovative methods of care that are integrated between primary health care providers and specialist teams in order to address long-term consequences of the disease and its treatment as well as to provide continued monitoring for recurrence. Our aim was to test the feasibility of a randomized controlled trial to compare a model of prostate cancer continuing and follow-up care integration, underpinned by digital technology, with usual care in terms of clinical and cost-effectiveness, patient-reported outcomes, and experience. A first phase of the study has included development of an online adaptive prostate specific Holistic Needs Assessment system (HNA), training for primary care-based nurses, training of an IT peer supporter, and interviews with health care professionals and men with prostate cancer to explore views of their care, experience of technology, and views of the proposed intervention. In Phase 2, men in the intervention arm will complete the HNA at home to help identify and articulate concerns and share them with their health care professionals, in both primary and specialist care. Participants in the control arm will receive usual care. Outcomes including quality of life and well-being, prostate-specific concerns, and patient enablement will be measured 3 times over a 9-month period. Findings from phase 1 indicated strong support for the intervention among men, including those who had had little experience of digital technology. Men expressed a range of views on ways that the online system might be used within a clinical pathway. Health care professionals gave valuable feedback on how the output of the assessment might be presented to encourage engagement and uptake by

  13. Integrated Care in Prostate Cancer (ICARE-P): Nonrandomized Controlled Feasibility Study of Online Holistic Needs Assessment, Linking the Patient and the Health Care Team

    Science.gov (United States)

    Dale, Jeremy; Roscoe, Julia; Hamborg, Thomas; Ahmedzai, Sam H; Arvanitis, Theodoros N; Badger, Douglas; James, Nicholas; Mendelsohn, Richard; Khan, Omar; Parashar, Deepak; Patel, Prashant

    2017-01-01

    Background The potential of technology to aid integration of care delivery systems is being explored in a range of contexts across a variety of conditions in the United Kingdom. Prostate cancer is the most common cancer in UK men. With a 10-year survival rate of 84%, there is a need to explore innovative methods of care that are integrated between primary health care providers and specialist teams in order to address long-term consequences of the disease and its treatment as well as to provide continued monitoring for recurrence. Objective Our aim was to test the feasibility of a randomized controlled trial to compare a model of prostate cancer continuing and follow-up care integration, underpinned by digital technology, with usual care in terms of clinical and cost-effectiveness, patient-reported outcomes, and experience. Methods A first phase of the study has included development of an online adaptive prostate specific Holistic Needs Assessment system (HNA), training for primary care-based nurses, training of an IT peer supporter, and interviews with health care professionals and men with prostate cancer to explore views of their care, experience of technology, and views of the proposed intervention. In Phase 2, men in the intervention arm will complete the HNA at home to help identify and articulate concerns and share them with their health care professionals, in both primary and specialist care. Participants in the control arm will receive usual care. Outcomes including quality of life and well-being, prostate-specific concerns, and patient enablement will be measured 3 times over a 9-month period. Results Findings from phase 1 indicated strong support for the intervention among men, including those who had had little experience of digital technology. Men expressed a range of views on ways that the online system might be used within a clinical pathway. Health care professionals gave valuable feedback on how the output of the assessment might be presented to

  14. A Nature-Based Social-Emotional Approach to Supporting Young Children's Holistic Development in Classrooms with and without Walls: The Social-Emotional and Environmental Education Development (SEED) Framework

    Science.gov (United States)

    Carter, Deborah

    2016-01-01

    This paper describes a nature-based social-emotional approach to supporting young children's holistic development that can be applied in a range of early childhood settings from forest kindergartens and nature-based preschools to more traditional center-based early childhood programs. "The Social-Emotional and Environmental Education…

  15. Curriculum Integration Using Enterprise Resource Planning: An Integrative Case Approach

    Science.gov (United States)

    Cannon, David M.; Klein, Helen A; Koste, Lori L.; Magal, Simha R.

    2004-01-01

    Efforts to achieve greater curriculum integration in schools of business have included team teaching, student group projects, multidisciplinary cases, and, more recently, the use of enterprise resource planning (ERP) systems. Although these approaches are beneficial, they tend to be implemented on an ad hoc basis rather than through curriculum…

  16. CANDU plant life management - An integrated approach

    International Nuclear Information System (INIS)

    Hopkins, J.R.

    1998-01-01

    An integrated approach to plant life management has been developed for CANDU reactors. Strategies, methods, and procedures have been developed for assessment of critical systems structures and components and for implementing a reliability centred maintenance program. A Technology Watch program is being implemented to eliminate 'surprises'. Specific work has been identified for 1998. AECL is working on the integrated program with CANDU owners and seeks participation from other CANDU owners

  17. Corporate governance survey: A holistic view for altruistic practice

    Directory of Open Access Journals (Sweden)

    Vijaya B. Marisetty

    2011-03-01

    Full Text Available Taking a holistic approach, this survey paper first reviews the literature on the four pillars of corporate governance, namely, investors, managers, directors, and law and regulation, and then integrates the four components to achieve a unified framework. Attempting to bridge the gap between principles and practice, the paper also incorporates the views of N R Narayana Murthy, founder member of Infosys, one of the most respected corporate governance practice leaders. The emphasis in Infosys, Mr. Murthy revealed, was not on any of the four dimensions but on the value system, ethics and integrity, and the focus on the competition was through better engagement with employees and customers.

  18. Holistic Framework For Establishing Interoperability of Heterogeneous Software Development Tools

    National Research Council Canada - National Science Library

    Puett, Joseph

    2003-01-01

    ...; however, this research focuses on establishing a holistic approach over the entire development effort where unrealized synergies and dependencies between all of the tools' artifacts can be visualized...

  19. Holistic Education from a Humanist Perspective

    OpenAIRE

    López Arrillaga, César Enrique

    2018-01-01

    This essay intends to approach the basic concepts of Holistic Education (Barrera, 2013) and a brief conceptual journey and main postulates of the humanist theory considered by the author on personality, (Carl, 1961), to establish the possible link of holistic education from a humanist perspective in the meeting of the postulates of Humanism in the teaching practice that allows the humanization of education, centered on human beings taking into account their abilities, abilities and skills, in...

  20. Dynamic cropping systems: Holistic approach for dryland agricultural systems in the northern Great Plains of North America

    Science.gov (United States)

    Cropping systems over the past century have developed greater crop specialization, more effectively conserve our soil and water resources, and are more resilient. The purpose of this chapter is to discuss the evolution of cropping systems in the Northern Great Plains and provide an approach to crop...

  1. Integrated Approach to User Account Management

    Science.gov (United States)

    Kesselman, Glenn; Smith, William

    2007-01-01

    IT environments consist of both Windows and other platforms. Providing user account management for this model has become increasingly diffi cult. If Microsoft#s Active Directory could be enhanced to extend a W indows identity for authentication services for Unix, Linux, Java and Macintosh systems, then an integrated approach to user account manag ement could be realized.

  2. Statistical inference an integrated Bayesianlikelihood approach

    CERN Document Server

    Aitkin, Murray

    2010-01-01

    Filling a gap in current Bayesian theory, Statistical Inference: An Integrated Bayesian/Likelihood Approach presents a unified Bayesian treatment of parameter inference and model comparisons that can be used with simple diffuse prior specifications. This novel approach provides new solutions to difficult model comparison problems and offers direct Bayesian counterparts of frequentist t-tests and other standard statistical methods for hypothesis testing.After an overview of the competing theories of statistical inference, the book introduces the Bayes/likelihood approach used throughout. It pre

  3. THE FEMINIST APPROACH TO PSYCHOTHERAPY INTEGRATION

    Directory of Open Access Journals (Sweden)

    Lorena Božac Deležan

    2011-12-01

    Full Text Available The goal of Integrative Psychotherapy is to establish full inner and external contact (Moursund & Erskine, 2004. The most important goal in feminist therapy is the transformation of an individual as well as the transformation of the society as a whole (Herlihy & Corey, 2004. In my work I attempt to integrate both: to help the client establish inner and external contact, but also help him/her to become aware and recognize inner messages connected with his/her gender and replace them with constructive beliefs of his/her own, as well as for him/her to learn, regardless of his/her gender, to trust his/her intuition and experience. In this article I present my approach to integration in psychotherapy and the way I use feminist principles in Integrative Psychotherapy.

  4. Integrative holism in psychiatric-mental health nursing.

    Science.gov (United States)

    Zahourek, Rothlyn P

    2008-10-01

    In this era of high-tech care, many Americans seek more holistic approaches and alternative and complementary treatments for health problems, including mental illness. Psychiatric-mental health (PMH) nurses need to be aware of these approaches as they assess clients, maintain a holistic approach, and in some cases, provide skilled, specific modalities. This article reviews holistic philosophy and integrative approaches relevant to PMH nurses. The emphasis is that whichever modality PMH nurses practice, a holistic framework is essential for providing optimal PMH care.

  5. Combining Project-based Instruction, Earth Science Content, and GIS Technology in Teacher Professional Development: Is this Holistic Approach Sustainable?

    Science.gov (United States)

    Rubino-Hare, L.; Bloom, N.; Claesgens, J.; Fredrickson, K.; Henderson-Dahms, C.; Sample, J. C.

    2012-12-01

    From 2009-2011, with support from the National Science Foundation (ITEST, DRL-0929846) and Science Foundation Arizona (MSAG-0412-09), educators, geologists and geographers at Northern Arizona University (NAU) partnered to offer professional development for interdisciplinary teams of secondary and middle school teachers with a focus on project-based instruction (PBI) using geospatial technologies (GST). While participating in professional development teachers received support and were held accountable to NAU staff. They implemented activities and pedagogical strategies presented, increased knowledge, skills, and confidence teaching with project-based instruction integrating GST, and their students demonstrated learning gains. Changes in student understanding are only observed when teachers continue to implement change, so the question remained: did these changes in practice sustain after official project support ended? In order to determine what, if anything, teachers sustained from the professional development and the factors that promoted or hindered sustained use of teaching with GST and PBI, data were collected one to two years following the professional development. Research questions included a) what pedagogical practices did teachers sustain following the professional learning experiences? and b) what contexts were present in schools that supported or limited the use of geospatial technologies as a teaching and learning tool? Findings from this study indicate that teachers fall into three categories of sustaining implementation - reformed implementers, mechanical implementers and non-implementers. School context was less of a factor in level of implementation than teachers' beliefs and philosophy of teaching and teachers' understanding of technology integration (teaching with technology vs. teaching technology). Case studies of teacher experiences will be presented along with implications for future professional development.

  6. A Prospective, Holistic, Multicenter Approach to Tracking and Understanding Bloodstream Infections in Pediatric Hematology-Oncology Patients.

    Science.gov (United States)

    Gaur, Aditya H; Bundy, David G; Werner, Eric J; Hord, Jeffrey D; Miller, Marlene R; Tang, Li; Lawlor, John P; Billett, Amy L

    2017-06-01

    OBJECTIVE To assess the burden of bloodstream infections (BSIs) among pediatric hematology-oncology (PHO) inpatients, to propose a comprehensive, all-BSI tracking approach, and to discuss how such an approach helps better inform within-center and across-center differences in CLABSI rate DESIGN Prospective cohort study SETTING US multicenter, quality-improvement, BSI prevention network PARTICIPANTS PHO centers across the United States who agreed to follow a standardized central-line-maintenance care bundle and track all BSI events and central-line days every month. METHODS Infections were categorized as CLABSI (stratified by mucosal barrier injury-related, laboratory-confirmed BSI [MBI-LCBI] versus non-MBI-LCBI) and secondary BSI, using National Healthcare Safety Network (NHSN) definitions. Single positive blood cultures (SPBCs) with NHSN defined common commensals were also tracked. RESULTS Between 2013 and 2015, 34 PHO centers reported 1,110 BSIs. Among them, 708 (63.8%) were CLABSIs, 170 (15.3%) were secondary BSIs, and 232 (20.9%) were SPBCs. Most SPBCs (75%) occurred in patients with profound neutropenia; 22% of SPBCs were viridans group streptococci. Among the CLABSIs, 51% were MBI-LCBI. Excluding SPBCs, CLABSI rates were higher (88% vs 77%) and secondary BSI rates were lower (12% vs 23%) after the NHSN updated the definition of secondary BSI (Papproach that could help better assess across-center and within-center differences in infection rates, including CLABSI. This approach enables informed decision making by healthcare providers, payors, and the public. Infect Control Hosp Epidemiol 2017;38:690-696.

  7. Holistic hybrid (Omni-channel) approach to retailing and customer experience: A review, conceptual framework and future research directions

    OpenAIRE

    Hickman, Ellie

    2015-01-01

    The manner in which customers shop is evolving and there has been an increase in customers shopping online and in physical shops using a multi-channel approach (Hsiao, Yen & Li, 2012). Customers now shop using mobile phones, tablets and have access to shopping sources 24 hours a day. Multi-channel shopping is where customers use multiple channels such as online, in-store, catalogues or mobile devices to purchase products or services (Zhang et al., 2010). Research has shown that multi-channel ...

  8. Earthworms and in vitro physiologically-based extraction tests: complementary tools for a holistic approach towards understanding risk at arsenic-contaminated sites.

    Science.gov (United States)

    Button, Mark; Watts, Michael J; Cave, Mark R; Harrington, Chris F; Jenkin, Gawen T

    2009-04-01

    The relationship of the total arsenic content of a soil and its bioaccumulation by earthworms (Lumbricus rubellus and Dendrodrilus rubidus) to the arsenic fraction bioaccessible to humans, measured using an in vitro physiologically-based extraction test (PBET), was investigated. Soil and earthworm samples were collected at 24 sites at the former arsenic mine at the Devon Great Consols (DGC) in southwest England (UK), along with an uncontaminated site in Nottingham, UK, for comparison. Analysis of soil and earthworm total arsenic via inductively coupled plasma mass spectrometry (ICP-MS) was performed following a mixed acid digestion. Arsenic concentrations in the soil were elevated (204-9,025 mg kg(-1)) at DGC. The arsenic bioaccumulation factor (BAF) for both earthworm species was found to correlate positively with the human bioaccessible fraction (HBF), although the correlation was only significant (P earthworms as complementary tools is explored as a holistic and multidisciplinary approach towards understanding risk at contaminated sites. Arsenic resistant earthworm species such as the L. rubellus populations at DGC are presented as a valuable tool for understanding risk at highly contaminated sites.

  9. Flavonoid and lignan intake in a Mediterranean population: proposal for a holistic approach in polyphenol dietary analysis, the Moli-sani Study.

    Science.gov (United States)

    Pounis, G; Di Castelnuovo, A; Bonaccio, M; Costanzo, S; Persichillo, M; Krogh, V; Donati, M B; de Gaetano, G; Iacoviello, L

    2016-03-01

    The objective of this study is to extract and assess data on the dietary intake of flavonoids and lignans in a healthy free-living Mediterranean population, using newly updated harmonized European Union food composition data. This work also aimed at analyzing in a holistic way the total content of the diet in major classes of polyphenols. Six thousand nine hundred and eighty-one men and 7048 women (aged ⩾ 35 years) of the Moli-sani cohort, randomly recruited from the general population, were analyzed. The European Prospective Investigation into Cancer (EPIC) and Nutrition-Food Frequency Questionnaire was used for dietary assessment. The polyphenol content of each food group was evaluated using Eurofir BioActive Substances in Food Information System and the United States Department of Agriculture food composition tables (FCTs), when data were missing. Flavonol, flavone, flavanone, flavanol, anthocyanin, isoflavone and lignan intakes were calculated and polyphenol antioxidant content (PAC) score (-28, 28) constructed, to assess the total content of the diet in these nutrients. Seasonal and citrus fruits, leafy, grain, pod and root vegetables, and onions and garlic accounted for different proportions (11-70%) of the total intake of different polyphenols. Within the Moli-sani population, men or older, or no/former smokers, or physically active or obese/overweight individuals presented higher consumption of flavonoids, lignans and PAC score (P for all 0, Pholistic approach in dietary analysis of polyphenol intake was proposed.

  10. Combining microsatellite, otolith shape and parasites community analyses as a holistic approach to assess population structure of Dentex dentex

    Science.gov (United States)

    Marengo, M.; Baudouin, M.; Viret, A.; Laporte, M.; Berrebi, P.; Vignon, M.; Marchand, B.; Durieux, E. D. H.

    2017-10-01

    The common dentex, Dentex dentex, is an iconic marine coastal fish of the Mediterranean Sea. Despite its economic and ecological importance, data on the population structure of this species are still very limited. The aim of this study was to identify the stock structure of the common dentex at relatively fine spatial scale around Corsica Island, using a combination of markers that have different spatial and temporal scales of integration: microsatellite DNA markers, otolith shape analysis and parasites communities. Microsatellite analysis indicated that there was no significant genetic differentiation in D. dentex between the four sampling sites around Corsica. Otolith shape analysis suggests one potential distinct population unit of D. dentex centered in one site (Cap Corse) varying in their degree of differentiation from those in the other zones. Multivariate analysis on parasite abundance data highlights to a lower extent two sites (Bonifacio and Galeria) with some connectivity between adjacent zones. The combination of these three markers together highlights the resulting three sites while giving complementary insights and an opportunity to compare their utility and potential to understand population interactions. A complex population structure around Corsican coasts is then proposed, providing a new perspective on common dentex fishery stock conservation and management strategies.

  11. Performance improvement integration: a whole systems approach.

    Science.gov (United States)

    Page, C K

    1999-02-01

    Performance improvement integration in health care organizations is a challenge for health care leaders. Required for accreditation by the Joint Commission on Accreditation of Healthcare Organizations (Joint Commission), performance improvement (PI) can be designed as a sustainable model for performance to survive in a turbulent period. Central Baptist Hospital developed a model for PI that focused on strategy established by the leadership team, delineated responsibility through the organizational structure of shared governance, and accountability for outcomes evidenced through the organization's profitability. Such an approach integrated into the culture of the organization can produce positive financial margins, positive customer satisfaction, and commendations from the Joint Commission.

  12. Clinical Holistic Health: Advanced Tools for Holistic Medicine

    Directory of Open Access Journals (Sweden)

    Søren Ventegodt

    2006-01-01

    Full Text Available According to holistic medical theory, the patient will heal when old painful moments, the traumatic events of life that are often called “gestalts”, are integrated in the present “now”. The advanced holistic physician’s expanded toolbox has many different tools to induce this healing, some that are more dangerous and potentially traumatic than others. The more intense the therapeutic technique, the more emotional energy will be released and contained in the session, but the higher also is the risk for the therapist to lose control of the session and lose the patient to his or her own dark side. To avoid harming the patient must be the highest priority in holistic existential therapy, making sufficient education and training an issue of highest importance. The concept of “stepping up” the therapy by using more and more “dramatic” methods to get access to repressed emotions and events has led us to a “therapeutic staircase” with ten steps: (1 establishing the relationship; (2 establishing intimacy, trust, and confidentiality; (3 giving support and holding; (4 taking the patient into the process of physical, emotional, and mental healing; (5 social healing of being in the family; (6 spiritual healing — returning to the abstract wholeness of the soul; (7 healing the informational layer of the body; (8 healing the three fundamental dimensions of existence: love, power, and sexuality in a direct way using, among other techniques, “controlled violence” and “acupressure through the vagina”; (9 mind-expanding and consciousness-transformative techniques like psychotropic drugs; and (10 techniques transgressing the patient's borders and, therefore, often traumatizing (for instance, the use of force against the will of the patient.We believe that the systematic use of the staircase will greatly improve the power and efficiency of holistic medicine for the patient and we invite a broad cooperation in scientifically testing the

  13. Clinical holistic health: advanced tools for holistic medicine.

    Science.gov (United States)

    Ventegodt, Søren; Clausen, Birgitte; Nielsen, May Lyck; Merrick, Joav

    2006-02-24

    According to holistic medical theory, the patient will heal when old painful moments, the traumatic events of life that are often called "gestalts", are integrated in the present "now". The advanced holistic physician's expanded toolbox has many different tools to induce this healing, some that are more dangerous and potentially traumatic than others. The more intense the therapeutic technique, the more emotional energy will be released and contained in the session, but the higher also is the risk for the therapist to lose control of the session and lose the patient to his or her own dark side. To avoid harming the patient must be the highest priority in holistic existential therapy, making sufficient education and training an issue of highest importance. The concept of "stepping up" the therapy by using more and more "dramatic" methods to get access to repressed emotions and events has led us to a "therapeutic staircase" with ten steps: (1) establishing the relationship; (2) establishing intimacy, trust, and confidentiality; (3) giving support and holding; (4) taking the patient into the process of physical, emotional, and mental healing; (5) social healing of being in the family; (6) spiritual healing--returning to the abstract wholeness of the soul; (7) healing the informational layer of the body; (8) healing the three fundamental dimensions of existence: love, power, and sexuality in a direct way using, among other techniques, "controlled violence" and "acupressure through the vagina"; (9) mind-expanding and consciousness-transformative techniques like psychotropic drugs; and (10) techniques transgressing the patient's borders and, therefore, often traumatizing (for instance, the use of force against the will of the patient). We believe that the systematic use of the staircase will greatly improve the power and efficiency of holistic medicine for the patient and we invite a broad cooperation in scientifically testing the efficiency of the advanced holistic

  14. Overview of integrative assessment of marine systems: the Ecosystem Approach in practice

    Directory of Open Access Journals (Sweden)

    Angel eBorja

    2016-03-01

    Full Text Available Traditional and emerging human activities are increasingly putting pressures on marine ecosystems and impacting their ability to sustain ecological and human communities. To evaluate the health status of marine ecosystems we need a science-based, integrated Ecosystem Approach, that incorporates knowledge of ecosystem function and services provided that can be used to track how management decisions change the health of marine ecosystems. Although many methods have been developed to assess the status of single components of the ecosystem, few exist for assessing multiple ecosystem components in a holistic way. To undertake such an integrative assessment, it is necessary to understand the response of marine systems to human pressures. Hence, innovative monitoring is needed to obtain data to determine the health of large marine areas, and in an holistic way. Here we review five existing methods that address both of these needs (monitoring and assessment: the Ecosystem Health Assessment Tool; a method for the Marine Strategy Framework Directive in the Bay of Biscay; the Ocean Health Index; the Marine Biodiversity Assessment Tool; and the Nested Environmental status Assessment Tool. We have highlighted their main characteristics and analyzing their commonalities and differences, in terms of: use of the Ecosystem Approach; inclusion of multiple components in the assessment; use of reference conditions; use of integrative assessments; use of a range of values to capture the status; weighting ecosystem components when integrating; determine the uncertainty; ensure spatial and temporal comparability; use of robust monitoring approaches; and address pressures and impacts. Ultimately, for any ecosystem assessment to be effective it needs to be: transparent and repeatable and, in order to inform marine management, the results should be easy to communicate to wide audiences, including scientists, managers and policymakers.

  15. Evaluating a novel tiered scarcity adjusted water budget and pricing structure using a holistic systems modelling approach.

    Science.gov (United States)

    Sahin, Oz; Bertone, Edoardo; Beal, Cara; Stewart, Rodney A

    2018-06-01

    Population growth, coupled with declining water availability and changes in climatic conditions underline the need for sustainable and responsive water management instruments. Supply augmentation and demand management are the two main strategies used by water utilities. Water demand management has long been acknowledged as a least-cost strategy to maintain water security. This can be achieved in a variety of ways, including: i) educating consumers to limit their water use; ii) imposing restrictions/penalties; iii) using smart and/or efficient technologies; and iv) pricing mechanisms. Changing water consumption behaviours through pricing or restrictions is challenging as it introduces more social and political issues into the already complex water resources management process. This paper employs a participatory systems modelling approach for: (1) evaluating various forms of a proposed tiered scarcity adjusted water budget and pricing structure, and (2) comparing scenario outcomes against the traditional restriction policy regime. System dynamics modelling was applied since it can explicitly account for the feedbacks, interdependencies, and non-linear relations that inherently characterise the water tariff (price)-demand-revenue system. A combination of empirical water use data, billing data and customer feedback on future projected water bills facilitated the assessment of the suitability and likelihood of the adoption of scarcity-driven tariff options for a medium-sized city within Queensland, Australia. Results showed that the tiered scarcity adjusted water budget and pricing structure presented was preferable to restrictions since it could maintain water security more equitably with the lowest overall long-run marginal cost. Copyright © 2018 Elsevier Ltd. All rights reserved.

  16. Qualitative modelling for the Caeté Mangrove Estuary (North Brazil): a preliminary approach to an integrated eco-social analysis

    Science.gov (United States)

    Ortiz, Marco; Wolff, Matthias

    2004-10-01

    The sustainability of different integrated management regimes for the mangrove ecosystem of the Caeté Estuary (North Brazil) were assessed using a holistic theoretical framework. As a way to demonstrate that the behaviour and trajectory of complex whole systems are not epiphenomenal to the properties of the small parts, a set of conceptual models from more reductionistic to more holistic were enunciated. These models integrate the scientific information published until present for this mangrove ecosystem. The sustainability of different management scenarios (forestry and fishery) was assessed. Since the exploitation of mangrove trees is not allowed according Brazilian laws, the forestry was only included for simulation purposes. The model simulations revealed that sustainability predictions of reductionistic models should not be extrapolated into holistic approaches. Forestry and fishery activities seem to be sustainable only if they are self-damped. The exploitation of the two mangrove species Rhizophora mangle and Avicenia germinans does not appear to be sustainable, thus a rotation harvest is recommended. A similar conclusion holds for the exploitation of invertebrate species. Our results suggest that more studies should be focused on the estimation of maximum sustainable yield based on a multispecies approach. Any reference to holistic sustainability based on reductionistic approaches may distort our understanding of the natural complex ecosystems.

  17. Addressing uncertainties in the ERICA Integrated Approach

    International Nuclear Information System (INIS)

    Oughton, D.H.; Agueero, A.; Avila, R.; Brown, J.E.; Copplestone, D.; Gilek, M.

    2008-01-01

    Like any complex environmental problem, ecological risk assessment of the impacts of ionising radiation is confounded by uncertainty. At all stages, from problem formulation through to risk characterisation, the assessment is dependent on models, scenarios, assumptions and extrapolations. These include technical uncertainties related to the data used, conceptual uncertainties associated with models and scenarios, as well as social uncertainties such as economic impacts, the interpretation of legislation, and the acceptability of the assessment results to stakeholders. The ERICA Integrated Approach has been developed to allow an assessment of the risks of ionising radiation, and includes a number of methods that are intended to make the uncertainties and assumptions inherent in the assessment more transparent to users and stakeholders. Throughout its development, ERICA has recommended that assessors deal openly with the deeper dimensions of uncertainty and acknowledge that uncertainty is intrinsic to complex systems. Since the tool is based on a tiered approach, the approaches to dealing with uncertainty vary between the tiers, ranging from a simple, but highly conservative screening to a full probabilistic risk assessment including sensitivity analysis. This paper gives on overview of types of uncertainty that are manifest in ecological risk assessment and the ERICA Integrated Approach to dealing with some of these uncertainties

  18. Evaluating the antidiabetic effects of Chinese herbal medicine: Xiao-Ke-An in 3T3-L1 cells and KKAy mice using both conventional and holistic omics approaches.

    Science.gov (United States)

    Yang, Zhenzhong; Wang, Linli; Zhang, Feng; Li, Zheng

    2015-08-13

    Xiao-Ke-An (XKA) is a Chinese medicine widely used for treating type 2 diabetes mellitus (T2D). It is composed of eight herbal medicines traditionally used for T2D, including Rehmannia glutinosa Libosch, Anemarrhena asphodeloides Bunge, Coptis chinensis Franch, etc. The aim of the present study was to investigate the antidiabetic effects of XKA with both conventional and holistic omics approaches. The antidiabetic effect of XKA was first investigated in 3T3-L1 cells to study the effect of XKA on adipogenesis in vitro. Oil Red O staining was performed to determine the lipid accumulation. The intracellular total cholesterol (TC) and triglyceride (TG) contents in XKA treated 3T3-L1 cells were also evaluated. The therapeutic effects of XKA was further evaluated in KKAy mice with both conventional and holistic omics approaches. Body weight, fasting and non-fasting blood glucose, and oral glucose tolerance were measured during the experiment. At the time of sacrifice, serum was collected for the measurement of TG, TC, high-density lipoprotein cholesterol (HDL-c) and low-density lipoprotein cholesterol (LDL-c). The liver, kidney, spleen, pancreas, heart and adipose tissues were harvested and weighted. The liver was used for further microarray experiment. Omics approaches were adopted to evaluate the holistic rebalancing effect of XKA at molecular network level. XKA significantly inhibited adipogenic differentiation, lowered the intracellular TC and TG contents in 3T3-L1 cells. XKA improved the glucose homeostasis and lipid metabolism, ameliorated insulin resistance in KKAy mice. Furthermore, XKA also exhibited effective therapeutic effects by reversing the molecular T2D disease network from an unbalanced state. This study investigated the antidiabetic effects of XKA with both conventional and holistic omics approaches, providing both phenotypic evidence and underlying action mechanisms for the clinical use of XKA treating T2D.

  19. Guidelines for planning interventions against external exposure in industrial area after a nuclear accident. Pt. 1. A holistic approach of countermeasure application

    International Nuclear Information System (INIS)

    Eged, K.; Kis, Z.; Andersson, K.G.; Roed, J.; Varga, K.

    2003-01-01

    Following a large-scale release of radioactivity into the environment, different urban, industrial and rural environments may be contaminated for many years. Currently, there is limited systematic consideration of long-term management to ensure sustainability of areas contaminated by long-lived radionuclides. To sustain acceptable living and working conditions in such areas it is important to be able to construct robust, effective restoration strategies which address the many different types of environment, land use and ways of life. The overall objective of the STRATEGY project (directly addressing Key Action 2: Nuclear Fission - Off-site emergency management in the Fifth Framework Programme) is to establish a decision framework to enable the selection of robust and practicable remediation strategies for Member States, which enable the long-term sustainable management of contaminated areas. The special objectives of the work carried out by GSF - Radiation Protection Institute and presented in this report was to contribute to the different urban/industrial parts of the STRATEGY project. Countermeasures being different from the usual urban ones and largely applicable in industrial area are collected and evaluated. The industrial area is defined here as such an area where productive and/or commercial activity is carried out. A good example is a supermarket or a factory. In designing restoration strategies to ensure the long-term sustainability of large and varied contaminated areas, there is a requirement to adopt a more holistic approach rather than simply selecting cost-effective countermeasures. The potentially negative consequences of restoration must be fully considered. The implementation of a remediation strategy may lead to a reduced collective dose, but increased dose to those implementing the strategies. Countermeasures may themselves generate waste and the practical consideration of disposal options has to be addressed. There is also a requirement that the

  20. Holistic approach to wood protection

    Science.gov (United States)

    Roger M. Rowell

    2006-01-01

    When untreated wood is exposed to adverse outdoor conditions, nature has a series of chemistries to degrade it to its original building blocks of carbon dioxide and water. Fungi, termites, heat, moisture, ultraviolet (UV) energy, and chemicals take their toll on the performance properties of wood. We tend to study each of these degradation chemistries as individual...

  1. A systems integration approach to the optimum operation and scheduling of biocide usage and discharge for seawater cooling systems

    KAUST Repository

    Mahfouz, Abdullah Bin

    2012-01-01

    The objective of this work is to develop a systematic approach to the optimal design and integration of seawater cooling systems in industrial facilities along with the usage and discharge of biocides. Specifically, the paper will address the following tasks: 1 identification of the reaction pathways for the biocide from the mixing basin to the discharge points 2 kinetic modelling of the biocide and by-products throughout the process 3 a process integration framework to provide a holistic approach to optimising the design and operation of the seawater cooling systems, along with the dosage and discharge systems. A hierarchical procedure is developed to first identify design modifications for heat integration and energy efficiency. Then, a multi-period, multi-segment optimisation formulation is developed and solved to identify the optimal operation and scheduling of biocide usage and discharge. A case study is solved to illustrate the applicability of the devised approach.

  2. Integration models: multicultural and liberal approaches confronted

    Science.gov (United States)

    Janicki, Wojciech

    2012-01-01

    European societies have been shaped by their Christian past, upsurge of international migration, democratic rule and liberal tradition rooted in religious tolerance. Boosting globalization processes impose new challenges on European societies, striving to protect their diversity. This struggle is especially clearly visible in case of minorities trying to resist melting into mainstream culture. European countries' legal systems and cultural policies respond to these efforts in many ways. Respecting identity politics-driven group rights seems to be the most common approach, resulting in creation of a multicultural society. However, the outcome of respecting group rights may be remarkably contradictory to both individual rights growing out from liberal tradition, and to reinforced concept of integration of immigrants into host societies. The hereby paper discusses identity politics upturn in the context of both individual rights and integration of European societies.

  3. Introduction to solid mechanics an integrated approach

    CERN Document Server

    Lubliner, Jacob

    2014-01-01

    This textbook presents for the first time in one text the concepts and processes covered in statics and mechanics of materials curricula following a systematic, topically integrated approach. Since the turn of the millennium, it has become common in engineering schools to combine the traditional undergraduate offerings in rigid-body statics (usually called “statics”) and deformable body mechanics (known traditionally as “strength of materials” or, more recently, “mechanics of materials”) into a single, introductory course in solid mechanics. Many textbooks for the new course sequentially meld pieces of existing, discrete books—sometimes, but not always, acknowledging the origin—into two halves covering Statics and Mechanics of Materials. In this volume, Professors Lubliner and Papadopoulos methodically combine the essentials of statics and mechanics of materials, illustrating the relationship of concepts throughout, into one "integrated" text. This book also: ·         Offers thorough...

  4. Pedagogic process modeling: Humanistic-integrative approach

    Directory of Open Access Journals (Sweden)

    Boritko Nikolaj M.

    2007-01-01

    Full Text Available The paper deals with some current problems of modeling the dynamics of the subject-features development of the individual. The term "process" is considered in the context of the humanistic-integrative approach, in which the principles of self education are regarded as criteria for efficient pedagogic activity. Four basic characteristics of the pedagogic process are pointed out: intentionality reflects logicality and regularity of the development of the process; discreteness (stageability in dicates qualitative stages through which the pedagogic phenomenon passes; nonlinearity explains the crisis character of pedagogic processes and reveals inner factors of self-development; situationality requires a selection of pedagogic conditions in accordance with the inner factors, which would enable steering the pedagogic process. Offered are two steps for singling out a particular stage and the algorithm for developing an integrative model for it. The suggested conclusions might be of use for further theoretic research, analyses of educational practices and for realistic predicting of pedagogical phenomena. .

  5. FUPOL: an Integrated Approach to Participative Policies

    Directory of Open Access Journals (Sweden)

    Silvana Tomic Rotim

    2014-05-01

    Full Text Available The Future Policy Modelling Project (FUPOL is a research project funded by the 7th framework program of the European Union. Its research focus are new technologies and methods for e-governance, e-participation and policy modelling. The FUPOL consortium consists of partners from European countries, China and Kenya. and comprises innovative multinational companies, leading research institutes, high-level political organizations as well as strong pilot partners. This paper describes the FUPOL new integrated approach to policy design and implementation including also specific examples from real life pilots in cities from different countries. FUPOL consists of an advanced policy lifecycle and an IT-solution with features supporting all phases of the proposed lifecycle. The FUPOL concept and functional modules as well as the technical architecture to achieve such a complete integration are described.

  6. Advances in Ecological Speciation: an integrative approach.

    Science.gov (United States)

    Faria, Rui; Renaut, Sebastien; Galindo, Juan; Pinho, Catarina; Melo-Ferreira, José; Melo, Martim; Jones, Felicity; Salzburger, Walter; Schluter, Dolph; Butlin, Roger

    2014-02-01

    The role of natural selection in promoting reproductive isolation has received substantial renewed interest within the last two decades. As a consequence, the study of ecological speciation has become an extremely productive research area in modern evolutionary biology. Recent innovations in sequencing technologies offer an unprecedented opportunity to study the mechanisms involved in ecological speciation. Genome scans provide significant insights but have some important limitations; efforts are needed to integrate them with other approaches to make full use of the sequencing data deluge. An international conference 'Advances in Ecological Speciation' organized by the University of Porto (Portugal) aimed to review current progress in ecological speciation. Using some of the examples presented at the conference, we highlight the benefits of integrating ecological and genomic data and discuss different mechanisms of parallel evolution. Finally, future avenues of research are suggested to advance our knowledge concerning the role of natural selection in the establishment of reproductive isolation during ecological speciation. © 2013 John Wiley & Sons Ltd.

  7. Development of a Quantitative Measure of Holistic Nursing Care.

    Science.gov (United States)

    Kinchen, Elizabeth

    2015-09-01

    Holistic care has long been a defining attribute of nursing practice. From the earliest years of its formal history, nursing has favored a holistic approach in the care of patients, and such an approach has become more important over time. The expansion of nursing's responsibility in delivering comprehensive primary care, the recognition of the importance of relationship-centered care, and the need for evidence-based legitimation of holistic nursing care and practices to insurance companies, policy-makers, health care providers, and patients highlight the need to examine the holistic properties of nursing care. The Holistic Caring Inventory is a theoretically sound, valid, and reliable tool; however, it does not comprehensively address attributes that have come to define holistic nursing care, necessitating the development of a more current instrument to measure the elements of a holistic perspective in nursing care. The development of a current and more comprehensive measure of holistic nursing care may be critical in demonstrating the importance of a holistic approach to patient care that reflects the principles of relationship-based care, shared decision-making, authentic presence, and pattern recognition. © The Author(s) 2014.

  8. The application of holistic risk management in the banking industry

    Directory of Open Access Journals (Sweden)

    J. Chibayambuya

    2007-12-01

    Full Text Available Purpose: The application of holistic risk management is fast becoming a standard measure of good governance in the business arena. What role can holistic risk management play in the management of risk in the financial services industry? The aim of this paper is to propose a holistic risk management framework for the management of risk. Design/Methodology/Approach: A comprehensive framework that covers the holistic view risk management is proposed/developed out of an extensive literature review. Findings: Given the deliberations of various frameworks, a holistic risk management is proposed. The proposed framework ensures that all components of risk management are taken into account when strategizing for risk management in general and holistic risk management in particular; thereby improving the management of risk in the banking industry. Implications: The article proposes a holistic approach to risk management which takes into account all the facets of risk management, e.g. analyzing, planning, strategy, communication, implementation, motivation, systems review and plan modification. This holistic approach, when implemented in the banking industry, can have a significant impact on the improved management of risk. Originality/Value: The new proposed holistic risk management framework offers a fresh perspective of strategizing for risk management in terms of risk analysis, risk planning, risk strategy, risk communication, risk implementation, risk motivation, risk review and risk plan modification.

  9. Indigenous Knowledge - A Holistic View Through a Food Security Lens

    Science.gov (United States)

    Angnaboogok, V.; Behe, C.; Daniel, R. G.

    2017-12-01

    Rapid changes occurring within the Arctic heighten the need to understand the multiple drivers pushing change and their cumulative impacts. Most importantly to better understand Arctic change a holistic view is needed that can only be achieved through bringing together multiple knowledge systems and scientific disciplines. Inuit have called the Arctic home from time immemorial acquiring a knowledge system. The Inuit knowledge system continues to grow, and holds methodologies and assessment processes that provide a pathway for holistically understanding the Arctic. This holistic view is largely attributed to a focus on relationships between system components, close attention to food webs, and a unique understanding of interconnecting systems. The Alaskan Inuit understanding of food security represents an Indigenous way of viewing the world - where food security encompasses complex and interlinked cultural and environmental systems. These systems are comprised of connections among the health of people, animals, and plants; the different states of land, sea, and air; and the cultural fabric held together by language, cultural expression, and social integrity. Within the Inuit knowledge system, it is impossible to disentangle some of these relationships; when we discuss an Inuit food security perspective, it is this interconnectivity and these relationships that we refer to. This presentation will offer an introduction to what it means to adopt a food security lens approach - a view needed to build our knowledge of the changes that are occurring and further our understanding of cumulative impacts while illuminating the nexus between all pieces that make up Arctic ecosystems.

  10. Creating Ripples: An Exploration of Sansei Women's Experiences of Expressive Practices in a Holistic Approach to Learning about Oppression and Privilege

    Science.gov (United States)

    Kaya, Katherine

    2013-01-01

    Although much has been written recently about holistic orientations to transformative learning, including its theoretical foundations and frameworks for designing learning experiences that engage multiple epistemologies, little is known about learners' experiences and about how engaging multiple epistemologies can foster learning that is…

  11. Enriching Careers and Lives: Introducing a Positive, Holistic, and Narrative Career Counseling Method that Bridges Theory and Practice

    Science.gov (United States)

    Zikic, Jelena; Franklin, Mark

    2010-01-01

    CareerCycles (CC) career counseling framework and method of practice integrates and builds on aspects of positive psychology. Through its holistic and narrative approach, the CC method seeks to collaboratively identify and understand clients' career and life stories. It focuses on their strengths, desires, preferences, assets, future…

  12. APPROACH FOR IMPROVING THE INTEGRATED SENSOR ORIENTATION

    Directory of Open Access Journals (Sweden)

    E. Mitishita

    2016-06-01

    Full Text Available The direct determination of exterior orientation parameters (EOP of aerial images via integration of the Inertial Measurement Unit (IMU and GPS is often used in photogrammetric mapping nowadays. The accuracies of the EOP depend on the accurate parameters related to sensors mounting when the job is performed (offsets of the IMU relative to the projection centre and the angles of boresigth misalignment between the IMU and the photogrammetric coordinate system. In principle, when the EOP values do not achieve the required accuracies for the photogrammetric application, the approach, known as Integrated Sensor Orientation (ISO, is used to refine the direct EOP. ISO approach requires accurate Interior Orientation Parameters (IOP and standard deviation of the EOP under flight condition. This paper investigates the feasibility of use the in situ camera calibration to obtain these requirements. The camera calibration uses a small sub block of images, extracted from the entire block. A digital Vexcel UltraCam XP camera connected to APPLANIX POS AVTM system was used to get two small blocks of images that were use in this study. The blocks have different flight heights and opposite flight directions. The proposed methodology improved significantly the vertical and horizontal accuracies of the 3D point intersection. Using a minimum set of control points, the horizontal and vertical accuracies achieved nearly one image pixel of resolution on the ground (GSD. The experimental results are shown and discussed.

  13. Incorporation of massage into psychotherapy: an integrative and conjoint approach.

    Science.gov (United States)

    Posadzki, Paul; Parekh-Bhurke, Sheetal

    2011-02-01

    This article presents the potential integration of psychotherapy and massage when considering the essence of their beneficial effects. The essence of this model of practice is multifaceted, combining principles from anatomy, physiology and neuroscience with psychotherapy to benefit patient care. It has been advocated that possessing multidisciplinary knowledge from these areas of science enhances psychotherapists' holistic care of their depressive patients. A narrative review of the literatures and a qualitative, conceptual synthesis has been performed to create a new theoretical-pragmatic construct. This article introduces the concept of massage practice as a part of psychotherapy practice and presents the potential integration of psychotherapeutic knowledge with clinical decision-making and the management of depressive symptoms. The authors emphasize the usefulness of multi- and interdisciplinary knowledge in the psychotherapeutic process and explain how this knowledge might be extrapolated and incorporated into theoretical and practical settings to benefit depressive patients. The justification for this concept is also presented. The principles set out in this article may be a useful source of information for psychotherapists concerned about their patients' holistic well-being in addition to the psychopathology for which they have sought treatment. Researchers and psychotherapists can obtain valuable and additional knowledge through cross-fertilization of ideas across the arguments presented here.

  14. Integrated management system - management standards evolution and the IAEA new approach

    International Nuclear Information System (INIS)

    Oliveira, Dirceu Paulo de; Zouain, Desiree Moraes

    2007-01-01

    The management standards application began in military and nuclear areas towards the end of Second World War, when some westerns countries developed quality standards to improve their means to assess suppliers' conditions to assure their products conformance, which was increasingly complex and required a higher degree of reliability. Afterwards, the quality standards application was extended to the consumer market focused on consumers' requirements satisfaction. Coming along the society crescent concern about quality of life, other management standards were developed, such as those dealing with environmental and sustainable development, occupational health and safety, social accountability and so on. As a consequence, the management process became complex. The management system integrated form approach makes possible the compatibility of distinct and complementary interests from several functions and disciplines involved and supply the absence of the organizations' holistic approach. According to this integrated management approach, the Agency - 'International Atomic Energy Agency' (IAEA) - decided to review the structure of the 50-C-Q standard - 'Quality Assurance for Safety in Nuclear Power Plants and Other Nuclear Installations', from 1996, publishing in 2006 the new GS-R-3 standard - 'The Management System for Facilities and Activities - Safety Requirements'. This work presents a brief evolution of management standards and integrated management approach, showing the Agency's new vision concerning this issue with the GS-R-3 standard publication. (author)

  15. Healing and Preventing Pain: Complementary and Integrative Approaches

    Science.gov (United States)

    ... page please turn JavaScript on. Feature: Pain Management Healing and Preventing Pain, Complementary and Integrative Approaches Past ... Pain Management" Articles Putting A Pause In Pain / Healing and Preventing Pain Complementary and Integrative Approaches / Pain ...

  16. Holistic education and complexity thinking

    NARCIS (Netherlands)

    Jörg, T.

    2007-01-01

    Paper proposal for the SIG Holistic Education at AERA 2007 Title: Holistic Education and Complexity Thinking Ton Jörg IVLOS Institute of Education University of Utrecht The Netherlands A.G.D.Jorg@ivlos.uu.nl ABSTRACT In this paper I link complexity thinking with Holistic Education (HE). It is a

  17. Beyond the buildingcentric approach: A vision for an integrated evaluation of sustainable buildings

    International Nuclear Information System (INIS)

    Conte, Emilia; Monno, Valeria

    2012-01-01

    The available sustainable building evaluation systems have produced a new environmental design paradigm. However, there is an increasing need to overcome the buildingcentric approach of these systems, in order to further exploit their innovate potential for sustainable building practices. The paper takes this challenge by developing a cross-scale evaluation approach focusing on the reliability of sustainable building design solutions for the context in which the building is situated. An integrated building–urban evaluation model is proposed based on the urban matrix, which is a conceptualisation of the built environment as a social–ecological system. The model aims at evaluating the sustainability of a building considering it as an active entity contributing to the resilience of the urban matrix. Few holistic performance indicators are used for evaluating such contribution, so expressing the building reliability. The discussion on the efficacy of the model shows that it works as a heuristic tool, supporting the acquisition of a better insight into the complexity which characterises the relationships between the building and the built environment sustainability. Shading new lights on the meaning of sustainable buildings, the model can play a positive role in innovating sustainable building design practices, thus complementing current evaluation systems. - Highlights: ► We model an integrated building–urban evaluation approach. ► The urban matrix represents the social–ecological functioning of the urban context. ► We introduce the concept of reliability to evaluate sustainable buildings. ► Holistic indicators express the building reliability. ► The evaluation model works as heuristic tool and complements other tools.

  18. Effects of holistic nursing course: a paradigm shift for holistic health practices.

    Science.gov (United States)

    Downey, Marty

    2007-06-01

    A study of an undergraduate course in holistic nursing was conducted to determine its impact on personal and professional health care practices. A mixed method design was used to examine responses on a sample of 200 participants. Results indicated a positive personal impact with continued application of concepts into professional health practices. Personal and professional nursing practices were influenced from 1 to 7 years after completing the holistic nursing course. After introduction of the concepts of self-care and holistic approaches to health, students and graduates experienced a shift in values and beliefs related to their own health practices. Continued exposure to holistic practices creates a pattern of awareness toward health that affects future personal and professional nursing practice, creating a paradigm shift for emerging nursing students and graduates from the course. This affects the manner in which nurses meet the needs of their clients in a variety of settings.

  19. Integrating manual and movement therapy with philosophical counseling for treatment of a patient with amyotrophic lateral sclerosis: a case study that explores the principles of holistic intervention.

    Science.gov (United States)

    Cottingham, J T; Maitland, J

    2000-03-01

    A patient (Travis) suffering from ALS received a holistic principle-based protocol that combined manual-movement techniques with philosophical counseling. After 4 sessions, he exhibited a remarkable improvement in head-neck alignment, balance/mobility, autonomic activity, and worldview for a 2-month span. These changes occurred only after his worldview underwent a shift from a dualistic split of mind and body to a nondualistic orientation. After this 2-month period of improvement, Travis' structural alignment and balance/mobility suddenly deteriorated rapidly. Yet, his enhanced worldview and autonomic tone continued through a final follow-up taken 17 weeks after the initial evaluation.

  20. Holistic approach to production systems from the perspective of lean manufacturing and viable systems model; Aproximacion holistica a los sistemas de produccion desde la perspectiva Lean Manufacturing y Modelos de Sistemas Viables

    Energy Technology Data Exchange (ETDEWEB)

    Puche Regaliza, J. C.; Costas Gual, J.

    2012-07-01

    The reductionism approach usually adopted by many organizations provokes too often a problem of sustain ability in the market over time in these organizations. To increase this sustain ability, we propose a structural and a behavioral change, in a way that the reductionism is replaced by an holistic approach appropriate to address the dynamic complexity inherent in any organization. With regard to structural change, we propose the use of Organizational Cybernetics and particularly the Viable System Model. With respect to behavior change, we propose the use of Lean Manufacturing paradigm. (Author)

  1. Holistic School Leadership: Development of Systems Thinking in School Leaders

    Science.gov (United States)

    Shaked, Haim; Schechter, Chen

    2018-01-01

    Background: Systems thinking is a holistic approach that puts the study of wholes before that of parts. It does not try to break systems down into parts in order to understand them; instead, it focuses attention on how the parts act together in networks of interactions. Purpose: This study explored the development of holistic school leadership--an…

  2. Complex Solutions for Complex Needs: Towards Holistic and Collaborative Practice

    Science.gov (United States)

    Beadle, Sally

    2009-01-01

    While the need for holistic health and social service responses is increasingly being articulated in Australia, the discussion is not always matched by improvements in service delivery. This project looked at one service setting where youth workers were encouraged to take a holistic approach to their clients' often-complex needs. Interviews with…

  3. Permutation statistical methods an integrated approach

    CERN Document Server

    Berry, Kenneth J; Johnston, Janis E

    2016-01-01

    This research monograph provides a synthesis of a number of statistical tests and measures, which, at first consideration, appear disjoint and unrelated. Numerous comparisons of permutation and classical statistical methods are presented, and the two methods are compared via probability values and, where appropriate, measures of effect size. Permutation statistical methods, compared to classical statistical methods, do not rely on theoretical distributions, avoid the usual assumptions of normality and homogeneity of variance, and depend only on the data at hand. This text takes a unique approach to explaining statistics by integrating a large variety of statistical methods, and establishing the rigor of a topic that to many may seem to be a nascent field in statistics. This topic is new in that it took modern computing power to make permutation methods available to people working in the mainstream of research. This research monograph addresses a statistically-informed audience, and can also easily serve as a ...

  4. Thermodynamics and statistical mechanics an integrated approach

    CERN Document Server

    Shell, M Scott

    2015-01-01

    Learn classical thermodynamics alongside statistical mechanics with this fresh approach to the subjects. Molecular and macroscopic principles are explained in an integrated, side-by-side manner to give students a deep, intuitive understanding of thermodynamics and equip them to tackle future research topics that focus on the nanoscale. Entropy is introduced from the get-go, providing a clear explanation of how the classical laws connect to the molecular principles, and closing the gap between the atomic world and thermodynamics. Notation is streamlined throughout, with a focus on general concepts and simple models, for building basic physical intuition and gaining confidence in problem analysis and model development. Well over 400 guided end-of-chapter problems are included, addressing conceptual, fundamental, and applied skill sets. Numerous worked examples are also provided together with handy shaded boxes to emphasize key concepts, making this the complete teaching package for students in chemical engineer...

  5. Stakeholder interaction within the ERICA Integrated Approach.

    Science.gov (United States)

    Zinger, I; Oughton, D H; Jones, S R

    2008-09-01

    Within the ERICA project, stakeholder involvement has been addressed within three main areas: generic interactions throughout the project, specific consultation by means of attendance to events and considerations as part of the ERICA Integrated Approach and Assessment Tool. The word stakeholders meant namely any individual or group who may be affected by or have an interest in an issue, and to include experts, lay-people and the public. An End-Users-Group (EUG) was set up to facilitate the two-way dialogue between the ERICA Consortium and stakeholders. The ERICA EUG consisted of representatives of 60 organisations ranging from regulatory bodies, national advisory bodies, academia, non-governmental organisations, industry, consultants and inter-governmental organisations. Stakeholder interaction was included from the very start of the project. Inputs from the EUG were recorded and in most instances incorporated within the development of the project and thus influenced and helped to shape some of the ERICA deliverables.

  6. MODELS OF TECHNOLOGY ADOPTION: AN INTEGRATIVE APPROACH

    Directory of Open Access Journals (Sweden)

    Andrei OGREZEANU

    2015-06-01

    Full Text Available The interdisciplinary study of information technology adoption has developed rapidly over the last 30 years. Various theoretical models have been developed and applied such as: the Technology Acceptance Model (TAM, Innovation Diffusion Theory (IDT, Theory of Planned Behavior (TPB, etc. The result of these many years of research is thousands of contributions to the field, which, however, remain highly fragmented. This paper develops a theoretical model of technology adoption by integrating major theories in the field: primarily IDT, TAM, and TPB. To do so while avoiding mess, an approach that goes back to basics in independent variable type’s development is proposed; emphasizing: 1 the logic of classification, and 2 psychological mechanisms behind variable types. Once developed these types are then populated with variables originating in empirical research. Conclusions are developed on which types are underpopulated and present potential for future research. I end with a set of methodological recommendations for future application of the model.

  7. Integrating systems Approaches into Pharmaceutical Sciences

    DEFF Research Database (Denmark)

    Westerhoff, H.V.; Mosekilde, Erik; Noe, C. R.

    2008-01-01

    During the first week of December 2007, the European Federation for Pharmaceutical Sciences (EUFEPS) and BioSim, the major European Network of Excellence on Systems Biology, held a challenging conference on the use of mathematical models in the drug development process. More precisely, the purpose...... of the conference was to promote the ‘Integration of Systems Approaches into Pharmaceutical Sciences’ in view of optimising the development of new effective drugs. And a challenge this is, considering both the high attrition rates in the pharmaceutical industry and the failure of finding definitive drug solutions...... for many of the diseases that plague mankind today. The conference was co-sponsored by the American College of Clinical Pharmacology, the European Center for Pharmaceutical Medicine, and the Swiss Society of Pharmaceutical Sciences and, besides representatives from the European Regulatory Agencies and FDA...

  8. Systematic Approach to Better Understanding Integration Costs

    Energy Technology Data Exchange (ETDEWEB)

    Stark, Gregory B. [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2015-09-01

    This research presents a systematic approach to evaluating the costs of integrating new generation and operational procedures into an existing power system, and the methodology is independent of the type of change or nature of the generation. The work was commissioned by the U.S. Department of Energy and performed by the National Renewable Energy Laboratory to investigate three integration cost-related questions: (1) How does the addition of new generation affect a system's operational costs, (2) How do generation mix and operating parameters and procedures affect costs, and (3) How does the amount of variable generation (non-dispatchable wind and solar) impact the accuracy of natural gas orders? A detailed operational analysis was performed for seven sets of experiments: variable generation, large conventional generation, generation mix, gas prices, fast-start generation, self-scheduling, and gas supply constraints. For each experiment, four components of integration costs were examined: cycling costs, non-cycling VO&M costs, fuel costs, and reserves provisioning costs. The investigation was conducted with PLEXOS production cost modeling software utilizing an updated version of the Institute of Electrical and Electronics Engineers 118-bus test system overlaid with projected operating loads from the Western Electricity Coordinating Council for the Sacramento Municipal Utility District, Puget Sound Energy, and Public Service Colorado in the year 2020. The test system was selected in consultation with an industry-based technical review committee to be a reasonable approximation of an interconnection yet small enough to allow the research team to investigate a large number of scenarios and sensitivity combinations. The research should prove useful to market designers, regulators, utilities, and others who want to better understand how system changes can affect production costs.

  9. Improvisation and the art of holistic nursing.

    Science.gov (United States)

    Hanley, Mary Anne; Fenton, Mary V

    2013-10-01

    The art of improvisation is an essential component of responding on the front lines of caring. Improvisation expresses the nurse's capacity to perceive the changing patterns of patients and their environments in ways that foster creative and innovative approaches to meeting healthcare needs. Many holistic nurses across the country are working on the front lines of caring, improvising and implementing projects to create change within their communities. This article examines improvisation within the context of the art and science of nursing, and proposes that improvisation reflects qualities within holistic nursing that are essential in contemporary health care.

  10. Holistic Education from a Humanist Perspective

    Directory of Open Access Journals (Sweden)

    César Enrique López Arrillaga

    2018-05-01

    Full Text Available This essay intends to approach the basic concepts of Holistic Education (Barrera, 2013 and a brief conceptual journey and main postulates of the humanist theory considered by the author on personality, (Carl, 1961, to establish the possible link of holistic education from a humanist perspective in the meeting of the postulates of Humanism in the teaching practice that allows the humanization of education, centered on human beings taking into account their abilities, abilities and skills, in a few words a tour of some important theoretical topics that will help build a vision of Hologogy in teachers.

  11. Quantum gravitation. The Feynman path integral approach

    International Nuclear Information System (INIS)

    Hamber, Herbert W.

    2009-01-01

    The book covers the theory of Quantum Gravitation from the point of view of Feynman path integrals. These provide a manifestly covariant approach in which fundamental quantum aspects of the theory such as radiative corrections and the renormalization group can be systematically and consistently addressed. The path integral method is suitable for both perturbative as well as non-perturbative studies, and is known to already provide a framework of choice for the theoretical investigation of non-abelian gauge theories, the basis for three of the four known fundamental forces in nature. The book thus provides a coherent outline of the present status of the theory gravity based on Feynman's formulation, with an emphasis on quantitative results. Topics are organized in such a way that the correspondence to similar methods and results in modern gauge theories becomes apparent. Covariant perturbation theory are developed using the full machinery of Feynman rules, gauge fixing, background methods and ghosts. The renormalization group for gravity and the existence of non-trivial ultraviolet fixed points are investigated, stressing a close correspondence with well understood statistical field theory models. Later the lattice formulation of gravity is presented as an essential tool towards an understanding of key features of the non-perturbative vacuum. The book ends with a discussion of contemporary issues in quantum cosmology such as scale dependent gravitational constants and quantum effects in the early universe. (orig.)

  12. USING BACH FLOWER IN HOLISTIC PSYCHOTHERAPY

    Directory of Open Access Journals (Sweden)

    Vagner Ferreira do Nascimento

    2017-05-01

    Full Text Available This is a narrative review from scientific literature that aimed to describe concepts and approaches for indications of the therapeutic use of Bach flower remedies in holistic psychotherapy. The review was developed in February 2016 from books, official documents and articles indexed in Lilacs and Scielo databases. Bach flower remedies is a therapeutic method that aims to restore the balance of human being, restoring its vital energy through holistic care. Because the flower essences act on psychic and emotional dimension of individual, when employed in holistic psychotherapy can provide greater autonomy, self-care and effectiveness compared to other alternative methods. The literature indicated that flower essence therapy is a safe practice and can be used in a complementary to health care, but should be performed by qualified professionals. It has also shown to be a promising and important area for nursing professional, but it still requires greater investment in research in the area to support the practice.

  13. Pressure Shell Approach to Integrated Environmental Protection

    Science.gov (United States)

    Kennedy, Kriss J.

    2011-01-01

    The next generation of exploration mission human systems will require environmental protection such as radiation protection that is effective and efficient. In order to continue human exploration, habitat systems will require special shells to protect astronauts from hostile environments. The Pressure Shell Approach to integrated environmental (radiation) protection is a multi-layer shell that can be used for multifunctional environmental protection. Self-healing, self-repairing nano technologies and sensors are incorporated into the shell. This shell consists of multiple layers that can be tailored for specific environmental protection needs. Mainly, this innovation focuses on protecting crew from exposure to micrometeorites, thermal, solar flares, and galactic cosmic ray (GCR) radiation. The Pressure Shell Approach consists of a micrometeoroid and secondary ejecta protection layer; a thin, composite shell placed in between two layers that is non-structural; an open cavity layer that can be filled with water, regolith, or polyethylene foam; a thicker composite shell that is a structural load bearing that is placed between two layers; and a bladder coating on the interior composite shell. This multi-layer shell creates an effective radiation protection system. Most of its layers can be designed with the materials necessary for specific environments. In situ materials such as water or regolith can be added to the shell design for supplemental radiation protection.

  14. Switching Markov chains for a holistic modeling of SIS unavailability

    International Nuclear Information System (INIS)

    Mechri, Walid; Simon, Christophe; BenOthman, Kamel

    2015-01-01

    This paper proposes a holistic approach to model the Safety Instrumented Systems (SIS). The model is based on Switching Markov Chain and integrates several parameters like Common Cause Failure, Imperfect Proof testing, partial proof testing, etc. The basic concepts of Switching Markov Chain applied to reliability analysis are introduced and a model to compute the unavailability for a case study is presented. The proposed Switching Markov Chain allows us to assess the effect of each parameter on the SIS performance. The proposed method ensures the relevance of the results. - Highlights: • A holistic approach to model the unavailability safety systems using Switching Markov chains. • The model integrates several parameters like probability of failure due to the test, the probability of not detecting a failure in a test. • The basic concepts of the Switching Markov Chains are introduced and applied to compute the unavailability for safety systems. • The proposed Switching Markov Chain allows assessing the effect of each parameter on the chemical reactor performance

  15. A knowledge integration approach to flood vulnerability

    Science.gov (United States)

    Mazzorana, Bruno; Fuchs, Sven

    2014-05-01

    Understanding, qualifying and quantifying vulnerability is an essential need for implementing effective and efficient flood risk mitigation strategies; in particular if possible synergies between different mitigation alternatives, such as active and passive measures, should be achieved. In order to combine different risk management options it is necessary to take an interdisciplinary approach to vulnerability reduction, and as a result the affected society may be willing to accept a certain degree of self-responsibility. However, due to differing mono-disciplinary approaches and regional foci undertaken until now, different aspects of vulnerability to natural hazards in general and to floods in particular remain uncovered and as a result the developed management options remain sub-optimal. Taking an even more fundamental viewpoint, the empirical vulnerability functions used in risk assessment specifically fail to capture physical principles of the damage-generating mechanisms to the build environment. The aim of this paper is to partially close this gap by discussing a balanced knowledge integration approach which can be used to resolve the multidisciplinary disorder in flood vulnerability research. Modelling techniques such as mathematical-physical modelling of the flood hazard impact to and response from the building envelope affected, and formative scenario analyses of possible consequences in terms of damage and loss are used in synergy to provide an enhanced understanding of vulnerability and to render the derived knowledge into interdisciplinary mitigation strategies. The outlined formal procedure allows for a convincing knowledge alignment of quantified, but partial, information about vulnerability as a result of the application of physical and engineering notions and valuable, but often underspecified, qualitative argumentation strings emerging from the adopted socio-economic viewpoint.

  16. Holistic processing of fingerprints by expert forensic examiners.

    Science.gov (United States)

    Vogelsang, Macgregor D; Palmeri, Thomas J; Busey, Thomas A

    2017-01-01

    Holistic processing is often characterized as a process by which objects are perceived as a whole rather than a compilation of individual features. This mechanism may play an important role in the development of perceptual expertise because it allows for rapid integration across image regions. The present work explores whether holistic processing is present in latent fingerprint examiners, who compare fingerprints collected from crime scenes against a set of standards taken from a suspect. We adapted a composite task widely used in the face recognition and perceptual expertise literatures, in which participants were asked to match only a particular half of a fingerprint with a previous image while ignoring the other half. We tested both experts and novices, using both upright and inverted fingerprints. For upright fingerprints, we found weak evidence for holistic processing, but with no differences between experts and novices with respect to holistic processing. For inverted fingerprints, we found stronger evidence of holistic processing, with weak evidence for differences between experts and novices. These relatively weak holistic processing effects contrast with robust evidence for holistic processing with faces and with objects in other domains of perceptual expertise. The data constrain models of holistic processing by demonstrating that latent fingerprint experts and novices may not substantively differ in terms of the amount of holistic processing and that inverted stimuli actually produced more evidence for holistic processing than upright stimuli. Important differences between the present fingerprint stimuli and those in the literature include the lack of verbal labels for experts and the absence of strong vertical asymmetries, both of which might contribute to stronger holistic processing signatures in other stimulus domains.

  17. Holistic pediatric veterinary medicine.

    Science.gov (United States)

    Pesch, Lisa

    2014-03-01

    Holistic veterinary medicine treats the whole patient including all physical and behavioral signs. The root cause of disease is treated at the same time as accompanying clinical signs. Herbal and nutritional supplements can help support tissue healing and proper organ functioning, thereby reducing the tendency of disease progression over time. Proper selection of homeopathic remedies is based on detailed evaluation of clinical signs. Herbal medicines are selected based on organ(s) affected and the physiologic nature of the imbalance. Many herbal and nutraceutical companies provide support for veterinarians, assisting with proper formula selection, dosing, drug interactions, and contraindications. Copyright © 2014 Elsevier Inc. All rights reserved.

  18. Mediterranean Storms: An Integrated Approach of Risk Management

    Science.gov (United States)

    Karageorgou, H.; Riza, E.; Linos, A.; Papanikolaou, D.

    2010-09-01

    Disaster by UN definition is "a serious disruption of the functioning of a community or a society, involving widespread human, material, economic, or environmental losses and impacts, which exceeds the ability of the affected community or society to cope using only its own resources". Mediterranean storms induce flash floods caused by excessive amounts of rainfall within a short lasting period of time. The intensity and duration of precipitation, region geomorphology, urbanization and different governmental emergency management structures trigger different consequences between Mediterranean countries. The integrated approach in management of storm risk represents a holistic perspective including interactions between government, science and technology institutions, developing agencies, private sector, NGOs and public. Local authorities and national government are responsible for the design, preparation and decision on storm risk management policies and strategies considering scientific risk identifying, assessing and understanding. Efficient governance management requires satisfied response to early warning systems, functionality of the affected systems upon which society depends and appropriate focus on variable interest, beliefs, values and ideologies between social groups. Also an appropriate balancing of benefits and costs in an efficient and equitable manner is important for the governance risk management. Natural sciences in corporation with the engineering science have developed effective early prediction, warning and monitoring systems on storm and flood risk. The health sciences use prediction systems for health related hazards and consequences and the social sciences research estimates the human resilience during disasters and the factors which affect and determine the human behavior. Also social sciences survey the response of public to early warning messages, the appropriate communicative methods to distributing messages and mechanisms to improve public

  19. The sustainable livelihoods approach

    DEFF Research Database (Denmark)

    Oelofse, Myles; Jensen, Henning Høgh

    2008-01-01

    food chain has on producers and their families, an analysis was conducted of the use of the Sustainable Livelihoods Approach (SLA). The SLA provides a holistic and integrative approach which researchers can use as the overriding frame for their research. The application of the approach is recommended...

  20. Nuclear power programme planning: An integrated approach

    International Nuclear Information System (INIS)

    2001-12-01

    The International Atomic Energy Agency (IAEA) has published material on different policy considerations in the introduction of nuclear power, primarily addressed to top level decision makers in government and industry in Member States. Several Member States and experts recommended to the IAEA to address the aspects of an integrated approach to nuclear power programme planning and to serve as guidance to those countries wishing to embark on a nuclear power programme. As a follow-up, the present publication is primarily intended to serve as guidance for executives and managers in Member States in planning for possible introduction of nuclear power plants in their electricity generating systems. Nuclear power programme planning, as dealt with in this publication, includes all activities that need to be carried out up to a well-founded decision to proceed with a project feasibility study. Project implementation beyond this decision is not in the scope of this publication. Although it is possible to use nuclear energy as a heat source for industrial processes, desalination and other heat applications, it is assumed in this publication that the planning is aimed towards nuclear power for electricity generation. Much of the information given would, however, also be relevant for planning of nuclear reactors for heat production. The publication was prepared within the framework of the IAEA programme on nuclear power planning, implementation and performance as a joint activity of the Nuclear Power Engineering Section and the Planning and Economic Studies Section (Division of Nuclear Power)

  1. Holistic aspects of quantum mechanics

    International Nuclear Information System (INIS)

    Pietschmann, H.

    1987-01-01

    Aspects of quantum mechanics irreconcilable with classical physics are outlined. Quantum mechanics started with a negative statement about reality, namely: it is impossible to determine momentum and position of a particle simultaneously. Meanwhile it has generated an impressive body of predictions which can be tested and have been confirmed by suitable experiments. As a consequence a naive, local, materialistic concept of reality must be abolished and a novel approach, the holistic is introduced. This is illustrated by some examples e.g. the Pauli exclusion principle for electrons, the electron capture decay of 135 La as a model of the wavefunction reduction, the Bohr radius of the atom, electron localisation in the atom. An example from the quantum field theory is the calculation of magnetic moments of electron and muon where a particle cannot be considered separately and all other particles must be taken into account. (G.Q.)

  2. Holistic management of diabetic foot

    Science.gov (United States)

    Lindarto, D.

    2018-03-01

    Diabetic foot ulcer (DFU) is the most costly and devastating complication of diabetes mellitus, which affect 15% of diabetic patients during their lifetime. DFUs are complex, chronic wounds, which have a major long-term impact on the morbidity, mortality and quality of patients’ lives. Individuals who develop a DFU are at greater risk of premature death, myocardial infarction and fatal stroke than those without a history of DFU. Unlike other chronic wounds, the development and progression of DFU is often complicated by wideranging diabetic changes, such as neuropathy and vascular disease. The management of DFU should be optimized by using a multidisciplinary team, due to a holistic approach to wound management is required. Based on studies, blood sugar control, wound debridement, advanced dressings and offloading modalities should always be a part of DFU management. Furthermore, surgery to heal chronic ulcer and prevent recurrence should be considered as an essential component of management in some cases.

  3. Safety in Schools: An Integral Approach

    Science.gov (United States)

    Gairin, Joaquin; Castro, Diego

    2011-01-01

    The present paper summarizes a research project into integral safety in schools. The aims of this particular research are, firstly, to evaluate the degree of integral safety in schools, secondly, to propose means for improving prevention and integral safety systems and thirdly, to identify the characteristics of safety culture. The field work was…

  4. Seeing the supermarket as a unit. Online management system as a holistic approach; Den Supermarkt als Ganzes sehen. Online-Managementsystem mit ganzheitlichem Ansatz

    Energy Technology Data Exchange (ETDEWEB)

    Wenzel, Martin [Hoerburger AG, Waltenhofen (Germany). Niederlassung Erfurt

    2011-02-15

    How can many subsidiaries be controlled effectively simultaneously in their most important building technical and plant technical parameters and supervised clearly? The contribution under consideration describes an open and holistic on-line software solution for automation and management of subsidiaries which can be distributed world-wide. The reduction of the costs of maintenance and the simplification of the plant operation, the transparency of technical processes of the subsidiaries, the optimization of building processes and finally the reduction of the energy consumption are thereby the most important advantages.

  5. Numerical approach to one-loop integrals

    International Nuclear Information System (INIS)

    Fujimoto, Junpei; Shimizu, Yoshimitsu; Kato, Kiyoshi; Oyanagi, Yoshio.

    1992-01-01

    Two numerical methods are proposed for the calculation of one-loop scalar integrals. In the first method, the singularity is cancelled by the symmetrization of the integrand and the integration is done by a Monte-Carlo method. In the second one, after the transform of the integrand into a standard form, the integral is reduced into a regular numerical integral. These methods provide us practical tools to evaluate one-loop Feynman diagrams with desired numerical accuracy. They are extended to the integral with numerator and the treatment of the one-loop virtual correction to the cross section is also presented. (author)

  6. Pengetahuan Dan Keterampilan Perawat Dalam Pelayanan Keperawatan Holistik Di Indonesian Holistic Tourist Hospital

    OpenAIRE

    Azizatunnisa, Nurul; Suhartini, Suhartini

    2012-01-01

    Health care nowadays provides holistic concept, which is focus on client's healing as the overall objectives including bio-psycho-socio-cultural-spiritual. This concept should be understood and applied by health practitioner, including nurses. Therefore, study about holistic nursing should be done, especially in Indonesian Holistic Tourist Hospital (IHTH) Purwakarta West Java as the first of health provider in Indonesia that used holistic approach. The objective of this research is to descri...

  7. An Integrated Computer-Aided Approach for Environmental Studies

    DEFF Research Database (Denmark)

    Gani, Rafiqul; Chen, Fei; Jaksland, Cecilia

    1997-01-01

    A general framework for an integrated computer-aided approach to solve process design, control, and environmental problems simultaneously is presented. Physicochemical properties and their relationships to the molecular structure play an important role in the proposed integrated approach. The sco...... and applicability of the integrated approach is highlighted through examples involving estimation of properties and environmental pollution prevention. The importance of mixture effects on some environmentally important properties is also demonstrated....

  8. CANDU plant life management - An integrated approach

    International Nuclear Information System (INIS)

    Charlebois, P.; Hart, R.S.; Hopkins, J.R.

    1998-01-01

    Commercial versions of CANDU reactors were put into service starting more than 25 years ago. The first unit of Ontario Hydro's Pickering A station was put into service in 1971, and Bruce A in 1977. Most CANDU reactors, however, are only now approaching their mid-life of 15 to 20 years of operation. In particular, the first series of CANDU 6 plants which entered service in the early 1980's were designed for a 30 year life and are now approaching mid life. The current CANDU 6 design is based on a 40 year life as a result of advancement in design and materials through research and development. In order to assure safe and economic operation of these reactors, a comprehensive CANDU Plant Life Management (PLIM) program is being developed from the knowledge gained during the operation of Ontario Hydro's Pickering, Bruce, and Darlington stations, worldwide information from CANDU 6 stations, CANDU research and development programs, and other national and international sources. This integration began its first phase in 1994, with the identification of most of the critical systems structures and components in these stations, and a preliminary assessment of degradation and mechanisms that could affect their fitness for service for their planned life. Most of these preliminary assessments are now complete, together with the production of the first iteration of Life Management Plans for several of the systems and components. The Generic CANDU 6 PLIM program is now reaching its maturity, with formal processes to systematically identify and evaluate the major CSSCs in the station, and a plan to ensure that the plant surveillance, operation, and maintenance programs monitor and control component degradation well within the original design specifications essential for the plant life attainment. A Technology Watch program is being established to ensure that degradation mechanisms which could impact on plant life are promptly investigated and mitigating programs established. The

  9. Global Environmental Change: An integrated modelling approach

    International Nuclear Information System (INIS)

    Den Elzen, M.

    1993-01-01

    Two major global environmental problems are dealt with: climate change and stratospheric ozone depletion (and their mutual interactions), briefly surveyed in part 1. In Part 2 a brief description of the integrated modelling framework IMAGE 1.6 is given. Some specific parts of the model are described in more detail in other Chapters, e.g. the carbon cycle model, the atmospheric chemistry model, the halocarbon model, and the UV-B impact model. In Part 3 an uncertainty analysis of climate change and stratospheric ozone depletion is presented (Chapter 4). Chapter 5 briefly reviews the social and economic uncertainties implied by future greenhouse gas emissions. Chapters 6 and 7 describe a model and sensitivity analysis pertaining to the scientific uncertainties and/or lacunae in the sources and sinks of methane and carbon dioxide, and their biogeochemical feedback processes. Chapter 8 presents an uncertainty and sensitivity analysis of the carbon cycle model, the halocarbon model, and the IMAGE model 1.6 as a whole. Part 4 presents the risk assessment methodology as applied to the problems of climate change and stratospheric ozone depletion more specifically. In Chapter 10, this methodology is used as a means with which to asses current ozone policy and a wide range of halocarbon policies. Chapter 11 presents and evaluates the simulated globally-averaged temperature and sea level rise (indicators) for the IPCC-1990 and 1992 scenarios, concluding with a Low Risk scenario, which would meet the climate targets. Chapter 12 discusses the impact of sea level rise on the frequency of the Dutch coastal defence system (indicator) for the IPCC-1990 scenarios. Chapter 13 presents projections of mortality rates due to stratospheric ozone depletion based on model simulations employing the UV-B chain model for a number of halocarbon policies. Chapter 14 presents an approach for allocating future emissions of CO 2 among regions. (Abstract Truncated)

  10. A management systems approach to pipeline integrity

    Energy Technology Data Exchange (ETDEWEB)

    Abes, J. [CC Technologies Canada, Calgary, AB (Canada)

    2008-07-01

    A management systems approach to pipeline integrity was discussed in terms of accident causation models, lessons from accidents, and management systems. Accident causation models include the Heinrich domino theory; epidemiological models; event chain models; and system-based models. A review of the Bellingham pipeline accident showed that if the pipeline had not been weakened by external damage, it likely would have been able to withstand the pressure that occurred on the day of the rupture, and the accident would not have happened. It was also determined that there was inadequate inspection of excavation work during the water treatment plant project and consequently, there was a failure to identify and repair the damage done to the pipeline. The presentation also addressed other findings, such as inaccurate evaluation of in-line pipeline inspection data; failure to manage and protect the supervisory control and data acquisition system (SCADA); and ineffective management oversight of construction and activation of products terminal. The Carlsbad pipeline explosion was also presented as another example of an accident. Several violations by El Paso were cited, including failure to ensure that qualified personnel performed internal corrosion control procedures; failure to perform necessary tests for corrosion; and failure to follow procedures for continuing surveillance of its facilities. Last, the presentation provided a definition of management systems and discussed the characteristics and elements of a management system. These elements included policy and leadership commitment; organizational structure and responsibilities; management of resources; communication plan; document and records management; operational controls; management of change; and continual improvement. 1 fig.

  11. Integrated NPP life cycle management - Agency's approach

    International Nuclear Information System (INIS)

    Gueorguiev, B.

    2002-01-01

    Full text: The number of nuclear power plants (NPPs) operating in the world has been roughly constant for the past seven years. There are 438 reactors of 353,489 MW(e) capacity in the world and they generated 2448.9 TWh in 2001 giving a total world operating experience with nuclear power of 10,363 years. About 230 units have reached already over 15 years of operation and significant number of these plants are fully depreciated. Share of nuclear power in electricity production sector in Member States utilising nuclear power plants represents a meaningful amount and in 14 countries it exceeds 30%. Therefore, a loss of this share should be covered by new installed capacities either from conventional or alternative sources of electricity generation. Recent forecasts, for nuclear power use over the next two decades range from ∼350 to ∼500 GW(e) worldwide. While assessing the need for any nuclear power related programmes there are several important factors that must be considered since even 350 GW(e) is a very large programme requiring several hundred thousand highly qualified personnel and a substantial infrastructure to assure its continued safe, reliable and cost-effective operation. It is important to assure reliable, safe and economic beneficial performance of the plant, which requires in turn an appropriated management of any activity connected with any taken period of a plant life starting from design and ending by the decided mode of decommissioning. The period between the first and the last payment for the activities connected with the existence of a plant could be defined as a life cycle of the plant. Such integrated approach requires considering the life cycle of the plant in a much broader sense than just operational life and is characterized by the variety of activities and their management represents in a whole a plant life management programme (PLIM). Therefore PLIM could be defined as an aggregate (totality) of technical, financial, economical and

  12. RISK INTEGRATION MECHANISMS AND APPROACHES IN BANKING INDUSTRY

    OpenAIRE

    JIANPING LI; JICHUANG FENG; XIAOLEI SUN; MINGLU LI

    2012-01-01

    Recently, the number of consultative documents and research papers that discuss risk integration has grown considerably. This paper presents a comprehensive review of the work done on risk integration in the banking industry. This survey includes: (1) risk integration methods within regulatory frameworks and the banking industry; (2) challenges of risk integration; (3) risk interaction mechanisms; (4) development of risk integration approaches; (5) risk interaction results: diversification ve...

  13. Developing a holistic strategy for integrated waste management within municipal planning: Challenges, policies, solutions and perspectives for Hellenic municipalities in the zero-waste, low-cost direction

    International Nuclear Information System (INIS)

    Zotos, G.; Karagiannidis, A.; Zampetoglou, S.; Malamakis, A.; Antonopoulos, I.-S.; Kontogianni, S.; Tchobanoglous, G.

    2009-01-01

    The present position paper addresses contemporary waste management options, weaknesses and opportunities faced by Hellenic local authorities. It focuses on state-of-the-art, tested as well as innovative, environmental management tools on a municipal scale and identifies a range of different collaboration schemes between local authorities and related service providers. Currently, a policy implementation gap is still experienced among Hellenic local authorities; it appears that administration at the local level is inadequate to manage and implement many of the general policies proposed; identify, collect, monitor and assess relevant data; and safeguard efficient and effective implementation of MSWM practices in the framework of integrated environmental management as well. This shortfall is partly due to the decentralisation of waste management issues to local authorities without a parallel substantial budgetary and capacity support, thus resulting in local activity remaining often disoriented and isolated from national strategies, therefore yielding significant planning and implementation problems and delays against pressing issues at hand as well as loss or poor use of available funds. This paper develops a systemic approach for MSWM at both the household and the non-household level, summarizes state-of-the-art available tools and compiles a set of guidelines for developing waste management master plans at the municipal level. It aims to provide a framework in the MSWM field for municipalities in Greece as well as other countries facing similar problems under often comparable socioeconomic settings

  14. Systems Pharmacology Dissecting Holistic Medicine for Treatment of Complex Diseases: An Example Using Cardiocerebrovascular Diseases Treated by TCM.

    Science.gov (United States)

    Wang, Yonghua; Zheng, Chunli; Huang, Chao; Li, Yan; Chen, Xuetong; Wu, Ziyin; Wang, Zhenzhong; Xiao, Wei; Zhang, Boli

    2015-01-01

    Holistic medicine is an interdisciplinary field of study that integrates all types of biological information (protein, small molecules, tissues, organs, external environmental signals, etc.) to lead to predictive and actionable models for health care and disease treatment. Despite the global and integrative character of this discipline, a comprehensive picture of holistic medicine for the treatment of complex diseases is still lacking. In this study, we develop a novel systems pharmacology approach to dissect holistic medicine in treating cardiocerebrovascular diseases (CCDs) by TCM (traditional Chinese medicine). Firstly, by applying the TCM active ingredients screened out by a systems-ADME process, we explored and experimentalized the signed drug-target interactions for revealing the pharmacological actions of drugs at a molecule level. Then, at a/an tissue/organ level, the drug therapeutic mechanisms were further investigated by a target-organ location method. Finally, a translational integrating pathway approach was applied to extract the diseases-therapeutic modules for understanding the complex disease and its therapy at systems level. For the first time, the feature of the drug-target-pathway-organ-cooperations for treatment of multiple organ diseases in holistic medicine was revealed, facilitating the development of novel treatment paradigm for complex diseases in the future.

  15. Decomposition approaches to integration without a measure

    Czech Academy of Sciences Publication Activity Database

    Greco, S.; Mesiar, Radko; Rindone, F.; Sipeky, L.

    2016-01-01

    Roč. 287, č. 1 (2016), s. 37-47 ISSN 0165-0114 Institutional support: RVO:67985556 Keywords : Choquet integral * Decision making * Decomposition integral Subject RIV: BA - General Mathematics Impact factor: 2.718, year: 2016 http://library.utia.cas.cz/separaty/2016/E/mesiar-0457408.pdf

  16. Holistic greenhouse gas management

    Energy Technology Data Exchange (ETDEWEB)

    Read, P. [Dept. of Applied and International Economics, Massey Univ. (New Zealand); Parshotam, A. [Inst. of Fundamental Sciences, Massey Univ. (New Zealand)

    2005-07-01

    A holistic greenhouse gas management strategy is described. The first stage is the growth of a large-scale global bio-energy market with world trade in bio-fuels and with a strategic stock of biomass raw material in new plantation forests. Later stages, more costly - as needs may be in response to possible future precursors of abrupt climate change - would involve linking CO2 capture and sequestration to bio-energy, yielding a negative emissions energy system. Illustrative calculations point to the feasibility of a return to pre-industrial CO{sub 2} levels before mid-century. This result is subject to significant caveats, but, prima facie, the first stage can provide several environmental and socio-economic side-benefits while yielding a positive financial return if oil prices remain above 35$/bbl. The vision is that the polluter pays principle can be turned to a greening of the earth. (orig.)

  17. Ultra-high performance liquid chromatography coupled with quadrupole/time of flight mass spectrometry based chemical profiling approach for the holistic quality control of complex Kang-Jing formula preparations.

    Science.gov (United States)

    Yang, Xiao-Huan; Cheng, Xiao-Lan; Qin, Bing; Cai, Zhuo-Ya; Cai, Xiong; Liu, Shao; Wang, Qi; Qin, Yong

    2016-05-30

    The Kang-Jing (KJ) formula is a compound preparation made from 12 kinds of herbs. So far, four different methods (M1-M4) have been documented for KJ preparation, but the influence of preparation methods on the holistic quality of KJ have remained unknown. In this study, a strategy was proposed to investigate the influence of different preparation methods on the holistic quality of KJ using ultra-high performance liquid chromatography coupled with quadrupole/time of flight mass spectrometry (UHPLC-QTOF-MS/MS) based chemical profiling. A total of 101 compounds mainly belonging to flavonoids, tanshinones, monoterpene glycosides, triterpenoid saponins, alkaloids, phenolic acids and volatile oils, were identified. Among these compounds, glaucine was detected only in M3/M4 samples, while two dehydrocorydaline isomers merely detected in M2/M3/M4 samples. Tetrahydrocolumbamine, ethylic lithospermic acid, salvianolic acid E and rosmarimic acid were only detected in M1/M3/M4 samples. In the subsequent quantitative analysis, 12 major compounds were determined by UHPLC-MS/MS. The proposed method was validated with respect to linearity, accuracy, precision and recovery. It was found that the contents of marker compounds varied significantly in samples prepared by different methods. These results demonstrated that preparation method does significantly affect the holistic quality of KJ. UHPLC-QTOF-MS/MS based chemical profiling approach is efficient and reliable for comprehensive quality evaluation of KJ. Collectively, this study provide the chemical evidence for revealing the material basis of KJ, and establish a simple and accurate chemical profiling method for its quality control. Copyright © 2016 Elsevier B.V. All rights reserved.

  18. Holistic evaluations of learning materials

    DEFF Research Database (Denmark)

    Bundsgaard, Jeppe; Hansen, Thomas Illum

    2011-01-01

    The aim of this paper is to present a holistic framework for evaluating learning materials and designs for learning. A holistic evaluation of learning material comprises investigations of - the potential learning potential, i.e. the affordances and challenges of the learning material...

  19. Decoding the integrated approach to yoga therapy: Qualitative evidence based conceptual framework.

    Science.gov (United States)

    Villacres, Maria Del Carmen; Jagannathan, Aarti; Nagarathna, R; Ramakrsihna, Jayashree

    2014-01-01

    The aim of this study was to define, decode, and append to the conceptual frame-work of the integrated approach to yoga therapy (IAYT). Four stakeholders who followed two in-patients with depression over a period of 2 weeks in the residential center Arogyadhama (of Swami Vivekananda Yoga Anusandana Samsthana, Bangalore, India) were interviewed before the start of the IAYT treatment and prior to discharge of the patient. The patients were also interviewed pre and post and were observed once during their session. The data from the audio recordings from eight in-depth interviews were transcribed manually and qualitative analysis was conducted. The conceptual frame-work of IAYT depicts that patient related factors ("co-operation of patient", "patients awareness of his/her condition"), therapist related factors ("ability to guide", "the assistance to the patients", "explanation of the exercises") and treatment related factors ("combination of psychiatric or Ayurvedic medication with yoga", "counseling during the IAYT treatment", duration of treatment), play an integrated role in reaching the "aim of IAYT" and experiencing "improvements and changes". The IAYT is a holistic program and the ability of the patient to cooperate with and integrate the available factors (therapist related and treatment related) could enable best results.

  20. An Integrated Open Approach to Capturing Systematic Knowledge for Manufacturing Process Innovation Based on Collective Intelligence

    Directory of Open Access Journals (Sweden)

    Gangfeng Wang

    2018-02-01

    Full Text Available Process innovation plays a vital role in the manufacture realization of increasingly complex new products, especially in the context of sustainable development and cleaner production. Knowledge-based innovation design can inspire designers’ creative thinking; however, the existing scattered knowledge has not yet been properly captured and organized according to Computer-Aided Process Innovation (CAPI. Therefore, this paper proposes an integrated approach to tackle this non-trivial issue. By analyzing the design process of CAPI and technical features of open innovation, a novel holistic paradigm of process innovation knowledge capture based on collective intelligence (PIKC-CI is constructed from the perspective of the knowledge life cycle. Then, a multi-source innovation knowledge fusion algorithm based on semantic elements reconfiguration is applied to form new public knowledge. To ensure the credibility and orderliness of innovation knowledge refinement, a collaborative editing strategy based on knowledge lock and knowledge–social trust degree is explored. Finally, a knowledge management system MPI-OKCS integrating the proposed techniques is implemented into the pre-built CAPI general platform, and a welding process innovation example is provided to illustrate the feasibility of the proposed approach. It is expected that our work would lay the foundation for the future knowledge-inspired CAPI and smart process planning.

  1. An integrated approach to change leadership.

    Science.gov (United States)

    Skelton-Green, Judith; Simpson, Beverley; Scott, Julia

    2007-01-01

    Leading change has become one of the essential core competencies of health professionals today. Since 2001, the authors have been the key designers and facilitators of the Dorothy Wylie Nursing Leadership Institute (DMW-NLI). The background, key characteristics and benefits of the DMW-NLI have been described in detail elsewhere (Simpson et al. 2002). One of the Institute's key features is that participants bring a change initiative that they wish to pursue and - during their time on site - we assist them in developing that project to the point where it has a strong chance of success. When we incorporated this aspect into the DMW-NLI program, we believed that opportunity to apply the learning of the Institute to a desired initiative in the home setting would add significant value, not only to the participants, but also to their sponsoring organizations. Further, it was our hope that we could develop a methodology to advance the change initiative, which would be a valuable tool that participants could use in future change projects.As we looked to the literature, we found no shortage of articles on change theory, as well as numerous tools and techniques for project management. However, we did not find one single approach or methodology that we felt was comprehensive yet concise enough to serve as a practical guide for those who wish to advance a change initiative in their practice settings today. Therefore, we developed an integrated conceptual framework and methodology for leading change initiatives, building on selected current and classic theories of change that are relevant today. Both the framework and methodology have proven very hardy, and will, we believe, be of interest to nurse leaders and other health professionals in leadership roles. This paper will provide a brief overview of relevant background literature on leading change initiatives, introduce the DMW-NLI Change Leadership conceptual framework, describe a number of activities that support the

  2. Selecting among five common modelling approaches for integrated environmental assessment and management

    NARCIS (Netherlands)

    Kelly, Rebecca A.; Jakeman, Anthony J.; Barreteau, Olivier; Borsuk, Mark E.; El-Sawah, Sondoss; Hamilton, Serena H.; Henriksen, Hans Jorgen; Kuikka, Sakari; Maier, Holger R.; Rizzoli, Andrea Emilio; van Delden, H.; Voinov, A.

    2013-01-01

    The design and implementation of effective environmental policies need to be informed by a holistic understanding of the system processes (biophysical, social and economic), their complex interactions, and how they respond to various changes. Models, integrating different system processes into a

  3. Data Integration The Relational Logic Approach

    CERN Document Server

    Genesereth, Michael

    2010-01-01

    Data integration is a critical problem in our increasingly interconnected but inevitably heterogeneous world. There are numerous data sources available in organizational databases and on public information systems like the World Wide Web. Not surprisingly, the sources often use different vocabularies and different data structures, being created, as they are, by different people, at different times, for different purposes. The goal of data integration is to provide programmatic and human users with integrated access to multiple, heterogeneous data sources, giving each user the illusion of a sin

  4. Holistic Marketing 3.0: Menuju Organisasi Spiritual

    OpenAIRE

    Gancar Candra Premananto

    2015-01-01

    Holistic Marketing is become new mantra for marketer in this 21 century. The concept builds on 4 pillars which are integrated marketing, internal marketing, performance marketing and relationship marketing. The point of that concept is about the important things is to make relationship to everybody and to every stakeholders. The concepts still on development process by Kotler & Keller. This conceptual article proposed that Holistic Marketing proposed by Kotler & Keller still discuss about hor...

  5. Holistic Health: Does It Really Include Mental Health?

    OpenAIRE

    McClanahan, Kimberly K.; Huff, Marlene B.; Omar, Hatim A.

    2006-01-01

    Holistic health, incorporating mind and body as equally important and unified components of health, is a concept utilized in some health care arenas in the United States (U.S.) over the past 30 years. However, in the U.S., mental health is not seen as conceptually integral to physical health and, thus, holistic health cannot be realized until the historical concept of mind-body dualism, continuing stigma regarding mental illness, lack of mental health parity in insurance, and inaccurate publi...

  6. Polymer reaction engineering, an integrated approach

    NARCIS (Netherlands)

    Meyer, T.; Keurentjes, J.T.F.; Meyer, T.; Keurentjes, J.T.F.

    2005-01-01

    Summary This chapter contains sections titled: Polymer Materials A Short History of Polymer Reaction Engineering The Position of Polymer Reaction Engineering Toward Integrated Polymer Reaction Engineering The Disciplines in Polymer Reaction Engineering The Future: Product-inspired Polymer Reaction

  7. AIM: An Integrated Approach to Organizational Improvement

    Directory of Open Access Journals (Sweden)

    Ronald A. Styron, Jr.

    2016-02-01

    Full Text Available This concept paper is based on the new problem-solving model of Blended Leadership called Alloy Improvement Model (AIM. This model consists of an integration of change theory, leadership theory, and democratic principles and practices to form a comprehensive problem-solving strategy for organizational leaders. The utilization of AIM will assist leaders in moving from problems to solutions while engaging stakeholders in a comprehensive, efficient, inclusive, informative, integrated and transparent process.

  8. Integrated crop protection as a system approach

    OpenAIRE

    Haan, de, J.J.; Wijnands, F.G.; Sukkel, W.

    2005-01-01

    New farming systems in vegetable production are required as demands for high quality products that do not pollute the environment are rising, and production risks are large and incomes low. The methodology of prototyping new systems is described, especially the themes, parameters and target values connected to integrated crop protection. The role of integrated crop protection in prototyping new systems is discussed. The results of twenty years working with this prototyping methodology are pre...

  9. The Impact of Technology Integration through a Transformative Approach

    Science.gov (United States)

    Cubillos, Jo Ann

    2013-01-01

    The integration of technology into classroom instruction in K-12 schools remains problematic. The problems associated with this integration are troubling, as technology integration may change a teacher's pedagogy toward more innovative approaches that increase student achievement. The purpose of this study was to document teachers' experiences as…

  10. Integrating Adult Learning and Technologies for Effective Education: Strategic Approaches

    Science.gov (United States)

    Wang, Victor C. X.

    2010-01-01

    As adult learners and educators pioneer the use of technology in the new century, attention has been focused on developing strategic approaches to effectively integrate adult learning and technology in different learning environments. "Integrating Adult Learning and Technologies for Effective Education: Strategic Approaches" provides innovative…

  11. HeartMath and Ubuntu integral healing approaches for social ...

    African Journals Online (AJOL)

    HeartMath and Ubuntu integral healing approaches for social coherence and physical activity. Stephen D. Edwards. Abstract. This research was motivated by many social health problems confronting planet earth. Its aim is to introduce HeartMath and Ubuntu as complimentary, integral healing approaches for promoting ...

  12. The Intersystem Model of Psychotherapy: An Integrated Systems Treatment Approach

    Science.gov (United States)

    Weeks, Gerald R.; Cross, Chad L.

    2004-01-01

    This article introduces the intersystem model of psychotherapy and discusses its utility as a truly integrative and comprehensive approach. The foundation of this conceptually complex approach comes from dialectic metatheory; hence, its derivation requires an understanding of both foundational and integrational constructs. The article provides a…

  13. Clinical Holistic Medicine: Holistic Treatment of Mental Disorders

    OpenAIRE

    Ventegodt, Søren; Andersen, Niels Jørgen; Neikrug, Shimshon; Kandel, Isack; Merrick, Joav

    2005-01-01

    We believe that holistic medicine can be used for patient's with mental health disorders. With holistic psychiatry, it is possible to help the mentally ill patient to heal existentially. As in holistic medicine, the methods are love or intense care, winning the trust of the patient, getting permission to give support and holding, and daring to be fully at the patient's service. Our clinical experiences have led us to believe that mental health patient's can heal if only you can make him or he...

  14. A Short History of Clinical Holistic Medicine

    OpenAIRE

    Ventegodt, Søren; Kandel, Isack; Merrick, Joav

    2007-01-01

    Clinical holistic medicine has its roots in the medicine and tradition of Hippocrates. Modern epidemiological research in quality of life, the emerging science of complementary and alternative medicine, the tradition of psychodynamic therapy, and the tradition of bodywork are merging into a new scientific way of treating patients. This approach seems able to help every second patient with physical, mental, existential or sexual health problem in 20 sessions over one year. The paper discusses ...

  15. Holistic Nursing in the Genetic/Genomic Era.

    Science.gov (United States)

    Sharoff, Leighsa

    2016-06-01

    Holistic nursing practice is an ever-evolving transformative process with core values that require continued growth, professional leadership, and advocacy. Holistic nurses are required to stay current with all new required competencies, such as the Core Competencies in Genetics for Health Professional, and, as such, be adept at translating scientific evidence relating to genetics/genomics in the clinical setting. Knowledge of genetics/genomics in relation to nursing practice, policy, utilization, and research influence nurses' responsibilities. In addition to holistic nursing competencies, the holistic nurse must have basic knowledge and skills to integrate genetics/genomics aspects. It is important for holistic nurses to enhance their overall knowledge foundation, skills, and attitudes about genetics to prepare for the transformation in health care that is already underway. Holistic nurses can provide an important perspective to the application of genetics and genomics, focusing on health promotion, caring, and understanding the relationship between caring and families, community, and society. Yet there may be a lack of genetic and genomic knowledge to fully participate in the current genomic era. This article will explore the required core competencies for all health care professionals, share linkage of holistic nurses in practice with genetic/genomic conditions, and provide resources to further one's knowledge base. © The Author(s) 2015.

  16. Investigation of Integrated Vehicle Health Management Approaches

    Science.gov (United States)

    Paris, Deidre

    2005-01-01

    This report is to present the work that was performed during the summer in the Advance Computing Application office. The NFFP (NASA Faculty Fellow Program) had ten summer faculty members working on IVHM (Integrated Vehicle Health Management) technologies. The objective of this project was two-fold: 1) to become familiar with IVHM concepts and key demonstrated IVHM technologies; and 2) to integrate the research that has been performed by IVHM faculty members into the MASTLAB (Marshall Avionic Software Test Lab). IVHM is a NASA-wide effort to coordinate, integrate and apply advanced software, sensors and design technologies to increase the level of intelligence, autonomy, and health state of future vehicles. IVHM is an important concept because it is consistent with the current plan for NASA to go to the moon, mars, and beyond. In order for NASA to become more involved in deep exploration, avionic systems will need to be highly adaptable and autonomous.

  17. THE FEMINIST APPROACH TO PSYCHOTHERAPY INTEGRATION

    OpenAIRE

    Lorena Božac Deležan

    2011-01-01

    The goal of Integrative Psychotherapy is to establish full inner and external contact (Moursund & Erskine, 2004). The most important goal in feminist therapy is the transformation of an individual as well as the transformation of the society as a whole (Herlihy & Corey, 2004). In my work I attempt to integrate both: to help the client establish inner and external contact, but also help him/her to become aware and recognize inner messages connected with his/her gender and replace them with con...

  18. Design of Integrated Circuits Approaching Terahertz Frequencies

    DEFF Research Database (Denmark)

    Yan, Lei

    In this thesis, monolithic microwave integrated circuits(MMICs) are presented for millimeter-wave and submillimeter-wave or terahertz(THz) applications. Millimeter-wave power generation from solid state devices is not only crucial for the emerging high data rate wireless communications but also...... heterodyne receivers with requirements of room temperature operation, low system complexity, and high sensitivity, monolithic integrated Schottky diode technology is chosen for the implementation of submillimeterwave components. The corresponding subharmonic mixer and multiplier for a THz radiometer system...

  19. Approaches to Integrated Building Design Environments

    DEFF Research Database (Denmark)

    Bagger-Petersen, Susanne C; Andersen, Tom

    1996-01-01

    This report discusses functional requirements and specification which needs to be defined and fulfilled to initiate development of an integrated building design environment. The purpose is to outline specifications for further discussion and development. The report documents the first phase...... in an ongoing project at the Technical University of Denmark. The overall project objective is to provide a theoretically well-founded prototype of an integrated IT-system which can serve as a device of feedback from practice and as a test-bed for the developed concept and architecture....

  20. Field theory a path integral approach

    CERN Document Server

    Das, Ashok

    2006-01-01

    This unique book describes quantum field theory completely within the context of path integrals. With its utility in a variety of fields in physics, the subject matter is primarily developed within the context of quantum mechanics before going into specialized areas.Adding new material keenly requested by readers, this second edition is an important expansion of the popular first edition. Two extra chapters cover path integral quantization of gauge theories and anomalies, and a new section extends the supersymmetry chapter, where singular potentials in supersymmetric systems are described.

  1. Development of Multisensory Integration Approach Model

    Science.gov (United States)

    Kumar, S. Prasanna; Nathan, B. Sami

    2016-01-01

    Every teacher expects optimum level of processing in mind of them students. The level of processing is mainly depends upon memory process. Most of the students have retrieval difficulties on past learning. Memory difficulties directly related to sensory integration. In these circumstances the investigator made an attempt to construct Multisensory…

  2. The Integration Movement in the Caribbean at Crossroads: Towards a New Approach of Integration

    OpenAIRE

    Uziel Nogueira

    1997-01-01

    The Institute for the Integration of Latin America and the Caribbean (INTAL) has inaugurated a Working Papers Series with the publication of a study by Uziel Nogueira, the Institute's Economist. Entitled "The Integration Movement in the Caribbean at the Crossroads: Towards a New Approach to Integration", the study opens with an overview of the movement towards integration among the English-speaking countries of the Caribbean. It continues with an analysis of the integration process during thi...

  3. An integrative approach to apprehend desistance.

    Science.gov (United States)

    F-Dufour, Isabelle; Brassard, Renée; Martel, Joane

    2015-05-01

    The process underlying desistance is still a strong subject of debate. This article seeks to introduce several core concepts of Archer's morphogenic approach to study how people desist from crime. At first, it discusses the primary existing theories of desistance. Then, this article demonstrates the usefulness of this approach by presenting empirical evidence drawn from semistructured interviews collected with 29 men who desisted from crime in an eastern province of Canada. The study demonstrates how this alternative approach allows for the consolidation of existing knowledge on desistance. Then implication of these findings for both theory and practice are discussed. © The Author(s) 2013.

  4. Evidence based herbal drug standardization approach in coping with challenges of holistic management of diabetes: a dreadful lifestyle disorder of 21st century.

    Science.gov (United States)

    Chawla, Raman; Thakur, Pallavi; Chowdhry, Ayush; Jaiswal, Sarita; Sharma, Anamika; Goel, Rajeev; Sharma, Jyoti; Priyadarshi, Smruti Sagar; Kumar, Vinod; Sharma, Rakesh Kumar; Arora, Rajesh

    2013-07-04

    Plants by virtue of its composition of containing multiple constituents developed during its growth under various environmental stresses providing a plethora of chemical families with medicinal utility. Researchers are exploring this wealth and trying to decode its utility for enhancing health standards of human beings. Diabetes is dreadful lifestyle disorder of 21st century caused due to lack of insulin production or insulin physiological unresponsiveness. The chronic impact of untreated diabetes significantly affects vital organs. The allopathic medicines have five classes of drugs, or otherwise insulin in Type I diabetes, targeting insulin secretion, decreasing effect of glucagon, sensitization of receptors for enhanced glucose uptake etc. In addition, diet management, increased food fiber intake, Resistant Starch intake and routine exercise aid in managing such dangerous metabolic disorder. One of the key factors that limit commercial utility of herbal drugs is standardization. Standardization poses numerous challenges related to marker identification, active principle(s), lack of defined regulations, non-availability of universally acceptable technical standards for testing and implementation of quality control/safety standard (toxicological testing). The present study proposed an integrated herbal drug development & standardization model which is an amalgamation of Classical Approach of Ayurvedic Therapeutics, Reverse Pharmacological Approach based on Observational Therapeutics, Technical Standards for complete product cycle, Chemi-informatics, Herbal Qualitative Structure Activity Relationship and Pharmacophore modeling and, Post-Launch Market Analysis. Further studies are warranted to ensure that an effective herbal drug standardization methodology will be developed, backed by a regulatory standard guide the future research endeavors in more focused manner.

  5. Improving Unsustainable Environmental Governance in South Africa: the Case for Holistic Governance

    Directory of Open Access Journals (Sweden)

    LJ Kotze

    2006-05-01

    Full Text Available Environmental law in South Africa has developed in a rapid fashion since the inception of the new constitutional dispensation in 1994. This development is evident from, inter alia, the constitutionalisation of the environmental right in section 24 of the Constitution of the Republic of South Africa, 1996. Section 24 contains amongst other provisions, directive principles that impose duties on government to protect the environment for present and future generations through reasonable legislative and other measures. It is apparent from section 24 that these measures should ensure environmental governance practices that are aimed at the achievement of sustainable results. The South African environmental governance regime is, however, characterised by fragmentation that may negate the achievement of sustainable environmental governance. It is argued in this article that, for environmental governance to become sustainable, it is necessary to integrate environmental governance efforts, possibly by way of a holistic approach to environmental governance. In light of the above, this article: investigates the nature and extent of fragmentation; explores reasons for fragmentation; discusses disadvantages of fragmented governance efforts in South Africa; investigates the concept of integration and holistic governance as means to achieve sustainable environmental governance results; and makes recommendations regarding the eventual achievement of integrated, holistic and sustainable environmental governance.

  6. Integrated approach to economical, reliable, safe nuclear power production

    International Nuclear Information System (INIS)

    1982-06-01

    An Integrated Approach to Economical, Reliable, Safe Nuclear Power Production is the latest evolution of a concept which originated with the Defense-in-Depth philosophy of the nuclear industry. As Defense-in-Depth provided a framework for viewing physical barriers and equipment redundancy, the Integrated Approach gives a framework for viewing nuclear power production in terms of functions and institutions. In the Integrated Approach, four plant Goals are defined (Normal Operation, Core and Plant Protection, Containment Integrity and Emergency Preparedness) with the attendant Functional and Institutional Classifications that support them. The Integrated Approach provides a systematic perspective that combines the economic objective of reliable power production with the safety objective of consistent, controlled plant operation

  7. The Saale-Project -A multidisciplinary approach towards sustainable integrative catchment management -

    Science.gov (United States)

    Bongartz, K.; Flügel, W. A.

    2003-04-01

    In the joint research project “Development of an integrated methodology for the sustainable management of river basins The Saale River Basin example”, coordinated by the Centre of Environmental Research (UFZ), concepts and tools for an integrated management of large river basins are developed and applied for the Saale river basin. The ultimate objective of the project is to contribute to the holistic assessment and benchmarking approaches in water resource planning, as required by the European Water Framework Directive. The study presented here deals (1) with the development of a river basin information and modelling system, (2) with the refinement of a regionalisation approach adapted for integrated basin modelling. The approach combines a user friendly basin disaggregation method preserving the catchment’s physiographic heterogeneity with a process oriented hydrological basin assessment for scale bridging integrated modelling. The well tested regional distribution concept of Response Units (RUs) will be enhanced by landscape metrics and decision support tools for objective, scale independent and problem oriented RU delineation to provide the spatial modelling entities for process oriented and distributed simulation of vertical and lateral hydrological transport processes. On basis of this RUs suitable hydrological modelling approaches will be further developed with strong respect to a more detailed simulation of the lateral surface and subsurface flows as well as the channel flow. This methodical enhancement of the well recognised RU-concept will be applied to the river basin of the Saale (Ac: 23 179 km2) and validated by a nested catchment approach, which allows multi-response-validation and estimation of uncertainties of the modelling results. Integrated modelling of such a complex basin strongly influenced by manifold human activities (reservoirs, agriculture, urban areas and industry) can only be achieved by coupling the various modelling approaches

  8. Design of Integrated Circuits Approaching Terahertz Frequencies

    OpenAIRE

    Yan, Lei; Johansen, Tom Keinicke

    2013-01-01

    In this thesis, monolithic microwave integrated circuits(MMICs) are presented for millimeter-wave and submillimeter-wave or terahertz(THz) applications. Millimeter-wave power generation from solid state devices is not only crucial for the emerging high data rate wireless communications but also important for driving THz signal sources. To meet the requirement of high output power, amplifiers based on InP double heterojunction bipolar transistor (DHBT) devices from the III-V Lab in Marcoussic,...

  9. Virtual integration: A game-theoretic approach

    OpenAIRE

    Schorer, Michael

    2014-01-01

    Embedded systems are playing a key role to enable the features of todays cars and other road vehicles. Advances in current hardware platforms of these embedded systems and growing implementation of features in software rather than in new hardware modules lead to new and continuously more complex automotive software systems. The integration process in the course of development of automotive software systems is a crucial and complex phase. An efficient combination of the set of components i...

  10. Concept for integrated environmental monitoring. Scientific approach

    Energy Technology Data Exchange (ETDEWEB)

    Haber, W [comp.; Schoenthaler, K; Kerner, H F; Koeppel, J; Spandau, L

    1998-09-01

    Despite considerable expenditures for environmental protection and intensified efforts in the areas of environmental research and monitoring, environmental damage increasingly occurs, sometimes with global effects, largely due to the lack of early diagnosis. In the past few years various institutions have therefore demanded improvements in environmental monitoring. The Council of Experts on Environmental Issues (`Rat von Sachverstaendigen fuer Umweltfragen`, SRU), in particular, in its `Environmental Report` of 1987 and in its Special Report on `General Ecological Environmental Monitoring` (1990) presented far-reaching demands for a nationwide ecological early warning system which should integrate the various local, regional, national, and even global monitoring levels, and which should encompass an environmental monitoring of entire ecosystems at representative locations. This is aimed at creating the prerequisites for - detection of long-term gradual environmental change, - confirmation of refutation of initial assumptions regarding the causes of these environmental changes, - permitting decisions on preventive actions to stabilize or improve environmental conditions and - making it possible to assess the success of environmental protection policies. This report includes an abbreviated version and documentation of the conference on the `Concept for Integrated Environmental Monitoring` and the final report `Specification of the Concept for Integrated Environmental Monitoring from the Perspective of Nature Conservation`. (orig.)

  11. Integrated care for diabetes - The Singapore Approach

    Directory of Open Access Journals (Sweden)

    Su Qian Yeo

    2012-03-01

    Full Text Available Background The prevalence of diabetes mellitus is 12.7% in Singapore. Managing people with diabetes in the community may be needed to reduce unnecessary utilisation of expensive specialist resources and to reduce hospital waiting times for patients with complications. Care Practice The Singapore General Hospital (SGH Delivering on Target (DOT Programme was launched in 2005 to right-site clinically stable diabetic patients from the hospital to private DOT GPs. The Chronic Disease Management Office (CDMO was established and a fully customised DOT information technology (IT system was developed. Three initiatives were implemented: (i Subsidised Drug Delivery Programme, (ii Diagnostic Tests Incentive Programme, and (iii Allied Healthcare Incentive Programme. Discussion Right-siting was enabled through patient incentives that eased the burden of out-of-pocket expenditure. Right Siting Officers (RSOs maintained a general oversight of the patient pathway. The integrated system supported shared care follow-up by enabling DOT GPs to share updates on the patients' health status with the referring specialists. Conclusion A coherent process across all healthcare providers similar to the SGH DOT Programme may facilitate efforts to shift the care for people with diabetes to the community and to provide integrated care. Successful integration may require incentives for institutional partners and patients.

  12. Validation of the Vanderbilt Holistic Face Processing Test.

    Science.gov (United States)

    Wang, Chao-Chih; Ross, David A; Gauthier, Isabel; Richler, Jennifer J

    2016-01-01

    The Vanderbilt Holistic Face Processing Test (VHPT-F) is a new measure of holistic face processing with better psychometric properties relative to prior measures developed for group studies (Richler et al., 2014). In fields where psychologists study individual differences, validation studies are commonplace and the concurrent validity of a new measure is established by comparing it to an older measure with established validity. We follow this approach and test whether the VHPT-F measures the same construct as the composite task, which is group-based measure at the center of the large literature on holistic face processing. In Experiment 1, we found a significant correlation between holistic processing measured in the VHPT-F and the composite task. Although this correlation was small, it was comparable to the correlation between holistic processing measured in the composite task with the same faces, but different target parts (top or bottom), which represents a reasonable upper limit for correlations between the composite task and another measure of holistic processing. These results confirm the validity of the VHPT-F by demonstrating shared variance with another measure of holistic processing based on the same operational definition. These results were replicated in Experiment 2, but only when the demographic profile of our sample matched that of Experiment 1.

  13. Validation of the Vanderbilt Holistic Face Processing Test.

    Directory of Open Access Journals (Sweden)

    Chao-Chih Wang

    2016-11-01

    Full Text Available The Vanderbilt Holistic Face Processing Test (VHPT-F is a new measure of holistic face processing with better psychometric properties relative to prior measures developed for group studies (Richler et al., 2014. In fields where psychologists study individual differences, validation studies are commonplace and the concurrent validity of a new measure is established by comparing it to an older measure with established validity. We follow this approach and test whether the VHPT-F measures the same construct as the composite task, which is group-based measure at the center of the large literature on holistic face processing. In Experiment 1, we found a significant correlation between holistic processing measured in the VHPT-F and the composite task. Although this correlation was small, it was comparable to the correlation between holistic processing measured in the composite task with the same faces, but different target parts (top or bottom, which represents a reasonable upper limit for correlations between the composite task and another measure of holistic processing. These results confirm the validity of the VHPT-F by demonstrating shared variance with another measure of holistic processing based on the same operational definition. These results were replicated in Experiment 2, but only when the demographic profile of our sample matched that of Experiment 1.

  14. A Holistic Approach to Estimating the Influence of Good Practices on Student Outcomes at Liberal Arts and non-Liberal Arts Institutions

    Directory of Open Access Journals (Sweden)

    Brian P. An

    2016-04-01

    Full Text Available Many higher education administrators and researchers have considered certain “good practices” of institutions as an instrumental way to improve student outcomes. Chickering and Gamson’s (1987 seven principles of good practice has been particularly salient in defining these practices. Often, prior studies only select some of the seven principles for their analysis. Even studies that consider several principles of good practice on student outcomes typically examine the net effect of each principle instead of assessing how these principles holistically influence student outcomes. Using structural equation modeling, we test a basic conceptual framework where we investigate the contribution of the seven principles on a global measure of good practices (GP, as well as the influence of GP on a multitude of student outcomes. We further test whether liberal arts colleges promote an institutional ethos of good practices as compared to non-liberal arts colleges. Overall, the majority (but not all of the principles affect GP. Moreover, we find partial evidence that liberal arts colleges foster an institutional ethos of good practices. Although a commitment to foster good practices may create a supportive environment that influences student outcomes, this commitment may lead to unintended consequences for those with little exposure to these good practices.

  15. Holistic Marketing 3.0: Menuju Organisasi Spiritual

    Directory of Open Access Journals (Sweden)

    Gancar Candra Premananto

    2015-12-01

    Full Text Available Holistic Marketing is become new mantra for marketer in this 21 century. The concept builds on 4 pillars which are integrated marketing, internal marketing, performance marketing and relationship marketing. The point of that concept is about the important things is to make relationship to everybody and to every stakeholders. The concepts still on development process by Kotler & Keller. This conceptual article proposed that Holistic Marketing proposed by Kotler & Keller still discuss about horizontal relationship. It is not include the important relationship that should be building by human, which is relationship to God. Those relationship can make organization can apply the concept of HabluminaLLAH, habluminannas dan rahmatan lil ’alamin. The concept proposed as Holistic Marketing 3.0, to make more complete and holistic relationship.

  16. Clinical Holistic Medicine: Chronic Infections and Autoimmune Diseases

    OpenAIRE

    Ventegodt, Søren; Merrick, Joav

    2005-01-01

    The consciousness-based (holistic) medical toolbox might be useful in general practice and in cases of recurrent infections and chronic infection or inflammation. From our clinical experiences, there is hope for improvement from a number of diseases caused by disorders affecting the regulation of the immune system when the physician includes the holistic medical approach.Our scientific understanding of the connection between consciousness and cellular order is still limited. Consciousness-bas...

  17. Validation of the Vanderbilt Holistic Face Processing Test

    OpenAIRE

    Wang, Chao-Chih; Ross, David A.; Gauthier, Isabel; Richler, Jennifer J.

    2016-01-01

    The Vanderbilt Holistic Face Processing Test (VHPT-F) is a new measure of holistic face processing with better psychometric properties relative to prior measures developed for group studies (Richler et al., 2014). In fields where psychologists study individual differences, validation studies are commonplace and the concurrent validity of a new measure is established by comparing it to an older measure with established validity. We follow this approach and test whether the VHPT-F measures the ...

  18. Validation of the Vanderbilt Holistic Face Processing Test.

    OpenAIRE

    Chao-Chih Wang; Chao-Chih Wang; David Andrew Ross; Isabel Gauthier; Jennifer Joanna Richler

    2016-01-01

    The Vanderbilt Holistic Face Processing Test (VHPT-F) is a new measure of holistic face processing with better psychometric properties relative to prior measures developed for group studies (Richler et al., 2014). In fields where psychologists study individual differences, validation studies are commonplace and the concurrent validity of a new measure is established by comparing it to an older measure with established validity. We follow this approach and test whether the VHPT-F measures the ...

  19. Integrated Artificial Intelligence Approaches for Disease Diagnostics.

    Science.gov (United States)

    Vashistha, Rajat; Chhabra, Deepak; Shukla, Pratyoosh

    2018-06-01

    Mechanocomputational techniques in conjunction with artificial intelligence (AI) are revolutionizing the interpretations of the crucial information from the medical data and converting it into optimized and organized information for diagnostics. It is possible due to valuable perfection in artificial intelligence, computer aided diagnostics, virtual assistant, robotic surgery, augmented reality and genome editing (based on AI) technologies. Such techniques are serving as the products for diagnosing emerging microbial or non microbial diseases. This article represents a combinatory approach of using such approaches and providing therapeutic solutions towards utilizing these techniques in disease diagnostics.

  20. Holistic nurses' stories of personal healing.

    Science.gov (United States)

    Smith, Marlaine C; Zahourek, Rothlyn; Hines, Mary Enzman; Engebretson, Joan; Wardell, Diane Wind

    2013-09-01

    The purpose of this study was to uncover the nature, experiences, and meaning of personal healing for holistic nurses through their narrative accounts. The study employed a qualitative descriptive design with methods of narrative and story inquiry. Participants were nurse attendees at an American Holistic Nurses' Association conference who volunteered for the study. They were invited to share a story about healing self or another. Twenty-five stories were collected; seven were about personal healing, and these are the focus of this analysis. Data were analyzed using a hybrid approach from narrative and story inquiry methods. Eleven themes were clustered under three story segments. The themes within the Call to the Healing Encounter are the following: recognition of the need to resolve a personal or health crisis, knowledge of or engagement in self-care practices, and reliance on intuitive knowing. Themes under the Experience of Healing are the following: connections; profound sensations, perceptions, and events; awareness of the reciprocal nature of healing; inner resolution: forgiveness, awakening, and acceptance; use of multiple holistic approaches; and witnessing manifestations of healing. The themes for Insights are the following: gratitude and appreciation and ongoing journey. A metastory synthesizing the themes is presented, and findings are related to existing literature on healing.

  1. Alcoholism: integrating approaches to influence policy

    African Journals Online (AJOL)

    Adele

    Most importantly that these disorders are treatable and treatment can be cost effective. It is crucial that we continually challenge our assumptions of best treatment practices. Rehabilitation programs in the. USA have in the last decade radically changed their approach to treatment, providing most treatment in ambulatory reha ...

  2. Founding Editorial: Embryology — An Integrated Approach

    Directory of Open Access Journals (Sweden)

    Michael Richardson

    2001-01-01

    Full Text Available We introduce the Embryology domain of TheScientificWorld and outline the scope and aims. We argue for an interdisciplinary approach to problems in develop-mental biology. Three areas are identified as being of particular relevance to this domain: evolutionary developmental biology, teratology, and descriptive or experimental embryology.

  3. New Theoretical Approach Integrated Education and Technology

    Science.gov (United States)

    Ding, Gang

    2010-01-01

    The paper focuses on exploring new theoretical approach in education with development of online learning technology, from e-learning to u-learning and virtual reality technology, and points out possibilities such as constructing a new teaching ecological system, ubiquitous educational awareness with ubiquitous technology, and changing the…

  4. Integrated approach to transmission services pricing

    International Nuclear Information System (INIS)

    Yu, C.W.; David, A.K.

    1999-01-01

    The paper presents an intuitively logical split between: (a) embedded, (b) operating, and (c) expansion cost based pricing and methodologies for implementation, for transmission services. A conceptually straightforward mechanism for the equitable allocation of transmission network embedded cost recovery based on capacity-use and reliability benefit is proposed, expansion cost is charged on a long-run marginal cost basis and finally, operating cost recovery is based on short-run marginal pricing. This is followed by co-ordinating these alternatives and integrating the pricing mechanisms to achieve appropriate price signals for bulk power users of transmission systems. (author)

  5. Holistic concept of marketing performance

    OpenAIRE

    Yu.V. Robul

    2011-01-01

    The scope of the article is to provide a critical analysis of ROMI as a metric of marketing performance, and to propose a more comprehensive construct of marketing efficiency, which considers a holistic nature of the concept of modern marketing. It is argued that ROMI be crucial insufficient as a marketing performanceindicator. In the holistic framework, a complex set of marketing performance metrics to be developed is outlined.

  6. Critical Perspectives of Pedagogical Approaches to Reversing the Order of Integration in Double Integrals

    Science.gov (United States)

    Tisdell, Christopher C.

    2017-01-01

    This paper presents some critical perspectives regarding pedagogical approaches to the method of reversing the order of integration in double integrals from prevailing educational literature on multivariable calculus. First, we question the message found in popular textbooks that the traditional process of reversing the order of integration is…

  7. Towards an integrative approach of improving indoor air quality

    Energy Technology Data Exchange (ETDEWEB)

    Bluyssen, Philomena M. [TNO Built Environment and Geosciences, P.O. Box 49, 2600 AA Delft (Netherlands)

    2009-09-15

    There seems to be a discrepancy between current Indoor Air Quality standards and end-users wishes and demands. Indoor air quality can be approached from three points of view: the human, the indoor air of the space and the sources contributing to indoor air pollution. Standards currently in use mainly address the indoor air of the space. ''Other or additional'' recommendations and guidelines are required to improve indoor air quality. Even though we do not fully understand the mechanisms behind the physical, chemical, physiological and psychological processes, it is still possible to identify the different ways to be taken regulatory, politically-socially (awareness), technically (process and product) and scientifically. Besides the fact that there is an urgent need to involve medicine and neuro-psychology in research to investigate the mechanisms behind dose-response, health effects and interactions between and with the other factors and parameters of the indoor environment and the human body and mind, a holistic approach is required including the sources, the air and last but not least the human beings (occupants) themselves. This paper mainly focuses on the European situation. (author)

  8. Undergraduate hematology – a more integrated approach

    Directory of Open Access Journals (Sweden)

    Di Carlofelice MA

    2016-11-01

    Full Text Available Matteo A Di Carlofelice,* Jack FT Cope*Faculty of Medicine, Imperial College London, London, UK*These authors contributed equally to this workAs fellow medical students we read with great interest the article by Mandan et al1 proposing a dedicated hematology rotation. The authors highlight a gap in clinical hematology teaching, particularly compared to “conventional rotations”.1 Their suggestion has merits and we agree with most of the points raised; however, propose instead for us to build on current teaching as opposed to establishing a new rotation.The integration of theoretical and practical learning was concluded to be beneficial to both teacher and student by Wrenn and Wrenn.2 In the original article it is mentioned that “clinical experience allows students to comprehend and apply this knowledge in practice, enabling the all-important integration of their learning”.1 As we agree that hematology overlaps with other specialties and therefore requires a thorough understanding, we value how a clinical attachment would be useful to solidify lecture-based teaching.View the original paper by Mandan et al.

  9. The drivers of sea lice management policies and how best to integrate them into a risk management strategy: An ecosystem approach to sea lice management.

    Science.gov (United States)

    Jackson, D; Moberg, O; Stenevik Djupevåg, E M; Kane, F; Hareide, H

    2018-06-01

    The control of sea lice infestations on cultivated Atlantic salmon is a major issue in many regions of the world. The numerous drivers which shape the priorities and objectives of the control strategies vary for different regions/jurisdictions. These range from the animal welfare and economic priorities of the producers, to the mitigation of any potential impacts on wild stocks. Veterinary ethics, environmental impacts of therapeutants, and impacts for organic certification of the produce are, amongst others, additional sets of factors which should be considered. Current best practice in both EU and international environmental law advocates a holistic ecosystem approach to assessment of impacts and risks. The issues of biosecurity and ethics, including the impacts on the stocks of species used as cleaner fish, are areas for inclusion in such a holistic ecosystem assessment. The Drivers, Pressures, State, Impacts, Responses (DPSIR) process is examined as a decision-making framework and potential applications to sea lice management are outlined. It is argued that this is required to underpin any integrated sea lice management (ISLM) strategy to balance pressures and outcomes and ensure a holistic approach to managing the issue of sea lice infestations on farmed stock on a medium to long-term basis. © 2017 The Authors. Journal of Fish Diseases Published by John Wiley & Sons Ltd.

  10. Holistic Processing of Chinese Characters

    Directory of Open Access Journals (Sweden)

    Alan Chun-Nang Wong

    2011-05-01

    Full Text Available Enhanced holistic processing (obligatory attention to all parts of an object has been associated with different types of perceptual expertise involving faces, cars, fingerprints, musical notes, English words, etc. Curiously Chinese characters are regarded as an exception, as indicated by the lack of holistic processing found for experts (Hsiao and Cottrell, 2009. The ceiling performance of experts, however, may have caused this null effect. We revisit this issue by adopting the often-used face-composite sequential-matching task to two-part Chinese characters. Participants matched the target halves (left or right of two characters while ignoring the irrelevant halves. Both Chinese readers (experts and non-Chinese readers (novices showed holistic processing. Follow-up experiments suggested different origins of the effects for the two groups. For experts, holistic processing was sensitive to the amount of experience with the characters, as it was larger for words than non-words (formed by swapping the two parts of a valid character. Novices, however, showed similar degree of holistic processing to words and non-words, suggesting that their effects were more related to their inefficient decomposition of a complex, character-like pattern into parts. Overall these findings suggest that holistic processing may be a marker of expertise with Chinese characters, contrary to previous claims.

  11. Leisure market segmentation : an integrated preferences/constraints-based approach

    NARCIS (Netherlands)

    Stemerding, M.P.; Oppewal, H.; Beckers, T.A.M.; Timmermans, H.J.P.

    1996-01-01

    Traditional segmentation schemes are often based on a grouping of consumers with similar preference functions. The research steps, ultimately leading to such segmentation schemes, are typically independent. In the present article, a new integrated approach to segmentation is introduced, which

  12. SESSION V: INTEGRATED APPROACHES IN LAND AND WATER ...

    African Journals Online (AJOL)

    SESSION V: INTEGRATED APPROACHES IN LAND AND WATER MANAGEMENT RESEARCH/LAND AND WATER MANAGEMENT ECONOMICS AND POLICY - Socioeconomic implications of improved forage species on smallholder farms in Kenya.

  13. Integration of case study approach, project design and computer ...

    African Journals Online (AJOL)

    Integration of case study approach, project design and computer modeling in managerial accounting education ... Journal of Fundamental and Applied Sciences ... in the Laboratory of Management Accounting and Controlling Systems at the ...

  14. Integrated landscape approach : Closing the gap between theory and application

    NARCIS (Netherlands)

    Bürgi, Matthias; Ali, Panna; Chowdhury, Afroza; Heinimann, Andreas; Hett, Cornelia; Kienast, Felix; Mondal, Manoranjan Kumar; Upreti, Bishnu Raj; Verburg, Peter H.

    2017-01-01

    Recently, the integrated landscape approach has gained increasing interest of the scientific community, as well as of organizations active in the field of sustainable development. However, the enthusiastic welcome is challenged by little consensus on theory, terminology and definitions. Moreover,

  15. Beyond nutrient-based food indices: a data mining approach to search for a quantitative holistic index reflecting the degree of food processing and including physicochemical properties.

    Science.gov (United States)

    Fardet, Anthony; Lakhssassi, Sanaé; Briffaz, Aurélien

    2018-01-24

    Processing has major impacts on both the structure and composition of food and hence on nutritional value. In particular, high consumption of ultra-processed foods (UPFs) is associated with increased risks of obesity and diabetes. Unfortunately, existing food indices only focus on food nutritional content while failing to consider either food structure or the degree of processing. The objectives of this study were thus to link non-nutrient food characteristics (texture, water activity (a w ), glycemic and satiety potentials (FF), and shelf life) to the degree of processing; search for associations between these characteristics with nutritional composition; search for a holistic quantitative technological index; and determine quantitative rules for a food to be defined as UPF using data mining. Among the 280 most widely consumed foods by the elderly in France, 139 solid/semi-solid foods were selected for textural and a w measurements, and classified according to three degrees of processing. Our results showed that minimally-processed foods were less hyperglycemic, more satiating, had better nutrient profile, higher a w , shorter shelf life, lower maximum stress, and higher energy at break than UPFs. Based on 72 food variables, multivariate analyses differentiated foods according to their degree of processing. Then technological indices including food nutritional composition, a w , FF and textural parameters were tested against technological groups. Finally, a LIM score (nutrients to limit) ≥8 per 100 kcal and a number of ingredients/additives >4 are relevant, but not sufficient, rules to define UPFs. We therefore suggest that food health potential should be first defined by its degree of processing.

  16. Path integral approach to multidimensional quantum tunnelling

    International Nuclear Information System (INIS)

    Balantekin, A.B.; Takigawa, N.

    1985-01-01

    Path integral formulation of the coupled channel problem in the case of multidimensional quantum tunneling is presented and two-time influence functionals are introduced. The two-time influence functionals are calculated explicitly for the three simplest cases: Harmonic oscillators linearly or quadratically coupled to the translational motion and a system with finite number of equidistant energy levels linearly coupled to the translational motion. The effects of these couplings on the transmission probability are studied for two limiting cases, adiabatic case and when the internal system has a degenerate energy spectrum. The condition for the transmission probability to show a resonant structure is discussed and exemplified. Finally, the properties of the dissipation factor in the adiabatic limit and its correlation with the friction coefficient in the classically accessible region are studied

  17. Aluminum recycling—An integrated, industrywide approach

    Science.gov (United States)

    Das, Subodh K.; Green, John A. S.; Kaufman, J. Gilbert; Emadi, Daryoush; Mahfoud, M.

    2010-02-01

    The aluminum industry is a leading proponent of global sustainability and strongly advocates the use of recycled metal. As the North American primary aluminum industry continues to move offshore to other geographic areas such as Iceland and the Middle East, where energy is more readily available at lower cost, the importance of the secondary (i.e., recycled metal) market in the U.S. will continue to increase. The purpose of this paper is to take an integrated, industry-wide look at the recovery of material from demolished buildings, shredded automobiles, and aging aircraft, as well as from traditional cans and other rigid containers. Attempts will be made to assess how the different alloys used in these separate markets can be recycled in the most energy-efficient manner.

  18. A boundary integral approach to unstable solidification

    International Nuclear Information System (INIS)

    Strain, J.

    1989-01-01

    We consider the supercooled Stefan problem with a general anisotropic curvature- and velocity-dependent boundary condition on the moving interface. We present numerical methods, based on an integral equation formulation and including a new algorithm for moving curves with curvature-dependent velocity. These methods compute a periodic interface with O(Δt) accuracy, where Δt is the time step. Previous work has been limited to short time spans and achieved slightly less than O(Δt 1/2 ) accuracy. Accurate numerical results are seen to agree with the predictions of linear stability theory. This agreement has eluded previous authors, because their numerical methods suffered from grid effects and their linear stability theory was incorrect. We study the long-time evolution of an unstable interface. Our computations exhibit the beginnings of a sidebranching instability when the boundary condition includes anisotropy and tip-splitting in the isotropic case. copyright 1989 Academic Press, Inc

  19. An integrated approach for prioritized process improvement.

    Science.gov (United States)

    Vanteddu, Gangaraju; McAllister, Charles D

    2014-01-01

    The purpose of this paper is to propose an integrated framework to simultaneously identify and improve healthcare processes that are important from the healthcare provider's and patient's perspectives. A modified quality function deployment (QFD) chart is introduced to the field of healthcare quality assurance. A healthcare service example is used to demonstrate the utility of the proposed chart. The proposed framework is versatile and can be used in a wide variety of healthcare quality improvement contexts, wherein, two different perspectives are needed to be considered for identifying and improving critical healthcare processes. The modified QFD chart used in conjunction with the stacked Pareto chart will facilitate the identification of key performance metrics from the patient's and the hospital's perspectives. Subsequently, the chief contributory factors at different levels are identified in a very efficient manner. Healthcare quality improvement professionals will be able to use the proposed modified QFD chart in association with stacked Pareto chart for effective quality assurance.

  20. Integrated management of water resources in urban water system: Water Sensitive Urban Development as a strategic approach

    Directory of Open Access Journals (Sweden)

    Juan Joaquín Suárez López

    2014-08-01

    Full Text Available The urban environment has to be concerned with the integrated water resources management, which necessarily includes the concept of basin unity and governance.  The traditional urban water cycle framework, which includes water supply, sewerage and wastewater treatment services, is being replaced by a holistic and systemic concept, where water is associated with urbanism and sustainability policies. This global point of view cannot be ignored as new regulations demand systemic and environmental approaches to the administrations, for instance, in the management of urban drainage and sewerage systems. The practical expression of this whole cluster interactions is beginning to take shape in several countries, with the definition of Low Impact Development and Water Sensitivity Urban Design concepts. Intends to integrate this new strategic approach under the name: “Water Sensitive Urban Development” (WSUD. With WSUD approach, the current urban water systems (originally conceived under the traditional concept of urban water cycle can be transformed, conceptual and physically, for an integrated management of the urban water system in new models of sustainable urban development. A WSUD implementing new approach to the management of pollution associated with stormwater in the urban water system is also presented, including advances in environmental regulations and incorporation of several techniques in Spain.

  1. Regional Integrated Silvopastoral Approaches to Ecosystem Management Project

    OpenAIRE

    CIPAV (Centre For Research on Sustainable Agricultural Production Systems); CATIE (Centro Agronomico Tropical de Investigacion y Ensenanza); NITLAPAN

    2007-01-01

    Metadata only record The Regional Integrated Silvopastoral Approaches to Ecosystem Management Project introduces the payment for environmental services approach to silvopastoral farmers in Colombia, Costa Rica, and Nicaragua. The objectives of the project are to "demonstrate and measure a) the effects the introduction of payment incentives for environmental services to farmers on their adoption of integrated silvopastoral farming systems in degraded pasture lands; and b) the resulting impr...

  2. Obsessive-compulsive disorder, which genes? Which functions? Which pathways? An integrated holistic view regarding OCD and its complex genetic etiology.

    Science.gov (United States)

    Bozorgmehr, Ali; Ghadirivasfi, Mohammad; Shahsavand Ananloo, Esmaeil

    2017-09-01

    Obsessive-compulsive disorder (OCD) is characterized by recurrent obtrusive and repetitive acts typically occurred following anxiety. In the last two decades, studies done on the gene sequences, large-scale and point mutations and gene-gene, gene-environment and gene-drug interactions have led to the discovery of hundreds of genes associated with OCD. Although each gene in turn is a part of the etiology of this disorder; however, OCD, like other mental disorders is complex and a comprehensive and integrated view is necessary to understand its genetic basis. In this study, through an extensive review of existing published studies, all genes associated with OCD were found. Then, in order to integrate the results, all the interactions between these genes were explored and the achievement was represented as an interactive genetic network. Furthermore, the reconstructed network was analyzed. It was found that GRIN2A, GRIN2B and GRIA2 are the most central nodes in the network. Functional and pathway enrichment analysis showed that glutamate-related pathways are the main deficient systems in patients with OCD. By studying genes shared between OCD and other diseases, it was cleared that OCD, epilepsy and some types of cancer have the most number of shared genes. The results of this study, in addition to reviewing the available results as a comprehensive and integrated manner, provide new hypotheses for future studies.

  3. Holistic study of an aquatic microcosm: theoretical and practical implications

    Energy Technology Data Exchange (ETDEWEB)

    Heath, R.T.

    1979-01-01

    The behavior of any system cannot by understood fully unless it is investigated as an intact unit over a range of states. The main task of holistic investigation is to determine the patterns of the set of responses and state transitions of a system and to examine the state space for trends, phases, and thresholds. Small laboratory ecosystems are ideal tools for holistic investigation of ecosystem function, because they are replicable and state settable. A small aquatic microcosm was characterized holistically as an example of this approach. Comparison of the nominal behavior of this system with its behavior under various degrees of cadmium stress (1, 10, 100 ppM Cd) indicated that holistic investigation of such systems is a sensitive and rapid means of assessing stress at the community level of organization.

  4. Approaches to the summability of divergent multidimensional integrals

    International Nuclear Information System (INIS)

    Vainikko, G M; Lifanov, I K

    2003-01-01

    Under discussion are various approaches to the concept of summability (finding the finite part - (f.p.)) of divergent integrals with integrand represented as a product of two functions, one with a parameter-dependent non-integrable singularity at one point of the integration and the other absolutely integrable. A study is made of summability methods which are based on the expansion of the absolutely integrable function in a Taylor series with centre at the singular point (f.p.), on the analytic continuation with respect to the parameter of the singularity (a.f.p.), and on integration by parts (f.p.p.). Formulae of changes of variables in such integrals are presented

  5. Integrating lifestyle approaches into osteoarthritis care

    Directory of Open Access Journals (Sweden)

    Garver MJ

    2015-09-01

    Full Text Available Matthew J Garver,1 Brian C Focht,2 Sarah J Taylor3 1Department of Kinesiology and Nutrition, Abilene Christian University, Abilene, TX, 2Department of Human Sciences, Ohio State University, Columbus, OH, 3School of Occupational Therapy, Texas Woman's University, Dallas, TX, USA Abstract: As the lifetime risk, societal cost, and overall functional impact of osteoarthritis (OA is imposing, it is imperative that clinicians provide an individualized care model for patients. Patients must be offered a multiplicity of care strategies and encouraged to embrace lifestyle approaches for self-managing the effects and symptoms of OA. Certainly, the attitude of the clinician and patient will directly influence receptivity and implementation of lifestyle approaches. This work proposes how the use of structured and routine assessments and cognitive therapy ideologies may complement a comprehensive treatment plan. Assessments described herein include objective and/or self-report measures of physical function, pain, attitude about social support, and sleep quality. Baseline assessments followed by systematic monitoring of the results may give patients and clinicians valuable insight into the effectiveness of the care plan. Empirical evidence from randomized trials with OA patients highlights the effectiveness of cognitive behavioral change strategies for addressing salient concerns for OA (pain control, mobility performance, and sleep quality. Cognitive restructuring can provide patients with renewed power in managing their disease. Cognitive therapy topics discussed presently include: 1 what is OA?, 2 effectiveness of exercise and FITT (frequency, intensity, time, and type principles for OA patients, 3 goal-setting and barriers, and 4 translating to independent care. Woven within the discussion about cognitive therapy are ideas about how the results from baseline assessments and group-mediated dynamics might assist more favorable outcomes. There are a plethora

  6. Qualitative Findings from an Experientially Designed Exercise Immunology Course: Holistic Wellness Benefits, Self-Efficacy Gains, and Integration of Prior Course Learning

    Science.gov (United States)

    Curry, Jennifer; Fazio-Griffith, Laura; Carson, Russell; Stewart, Laura

    2010-01-01

    Experiential education is a well documented approach to engaging student learners. This manuscript presents findings from a qualitative inquiry, specifically focus group discussions, investigating the perceptions of 28 student participants in a learning opportunity provided to a kinesiology class involving structured group exercise (marathon…

  7. Integrated microsystems packaging approach with LCP

    Science.gov (United States)

    Jaynes, Paul; Shacklette, Lawrence W.

    2006-05-01

    Within the government communication market there is an increasing push to further miniaturize systems with the use of chip-scale packages, flip-chip bonding, and other advances over traditional packaging techniques. Harris' approach to miniaturization includes these traditional packaging advances, but goes beyond this level of miniaturization by combining the functional and structural elements of a system, thus creating a Multi-Functional Structural Circuit (MFSC). An emerging high-frequency, near hermetic, thermoplastic electronic substrate material, Liquid Crystal Polymer (LCP), is the material that will enable the combination of the electronic circuit and the physical structure of the system. The first embodiment of this vision for Harris is the development of a battlefield acoustic sensor module. This paper will introduce LCP and its advantages for MFSC, present an example of the work that Harris has performed, and speak to LCP MFSCs' potential benefits to miniature communications modules and sensor platforms.

  8. AN INTEGRATED APPROACH FOR LINKED DATA BROWSING

    Directory of Open Access Journals (Sweden)

    W. Beek

    2017-07-01

    Full Text Available The Netherlands' Cadastre, Land Registry and Mapping Agency – in short Kadaster – collects and registers administrative and spatial data on property and the rights involved. Currently, the Kadaster is publishing its geo-spatial data assets as Linked Open Data. The Kadaster manages hundreds of datasets that describe hundreds of millions of geospatial objects, including all Dutch buildings, roads, and forests. The Kadaster exposes this large collection of data to thousands of daily users that operate from within different contexts and that need to be supported in different use cases. Therefore, Kadaster must offer diverse, yet complementary, approaches for browsing and exploring the data it publishes. Specifically, it supports the following paradigms for browsing and exploring its data assets: hierarchical browsing, graph navigation, faceted browsing, and tabular browsing. These paradigms are useful for different tasks, cover different use cases, and are implemented by reusing and/or developing Open Source libraries and applications.

  9. Preregularization and the path integral approach to the chiral anomaly

    International Nuclear Information System (INIS)

    Elias, V.; McKeon, G.; Steele, T.; Mann, R.B.; Treml, T.F.; Sherry, T.N.

    1987-01-01

    We explore the connection between perturbative and non-perturbative (path-integral) approaches to the axial anomaly. In particular, we show how the Jacobian associated with the fermionic measure corresponding to local axial transformations may be calculated directly from shift-of-integration-variable surface terms in four Euclidean dimensions. No regularization (explicit parametrization of UV infinities) is required in this approach, but invariance of the Jacobian under vector gauge transformations (i.e. preregularization) is required to remove a variable-of-integration ambiguity within the expression for the Jacobian of the fermionic measure. (orig.)

  10. Improved clean development mechanism and joint implementation to promote holistic sustainable development - an integrated policy and methodology for international energy collaboration

    Energy Technology Data Exchange (ETDEWEB)

    Kua Harn Wei

    2007-07-01

    The current Clean Development Mechanism/Joint Implementation framework does not emphasize on wholistic sustainability of energy projects. The Golden Standard was a good example of how this framework can be fine-tuned. However, it does not explicitly incentivize the adoption of the sustainability standards it outlines. A 4-element integrated policy strategy is proposed. A Sustainability Assessment Matrix is constructed to evaluate project proposals' sustainability performance. The Probational Sustainability Performance Demand requires continual monitoring of this performance of approved projects throughout a designated probation period. The involved countries will be awarded Sustainability Credits (measured with the matrix) in installments according to their performance within this period. The Probational Emission Reduction Demand requires investing countries to meet moderated emission reduction targets in order for them to claim the certified emission reductions/ emission reduction credits and their share of Sustainability Credits. These credits are converted into Sustainability Assistance Funds, which can be channeled back to finance either the approved projects or independent renewable energy projects in the involved countries. The MIT Energy Cost Model is used to estimate the required amount and identify the forms of such assistance package. Finally, an integrated policymaking framework is suggested to execute and monitor these interconnected policy elements. (auth)

  11. Rethinking Recovery: Incorporating Holistic Nursing Perspectives in Poststroke Care.

    Science.gov (United States)

    Peterson-Burch, Frances; Reuter-Rice, Karin; Barr, Taura L

    Stroke is a life-changing experience. Current treatments focus on treating the condition, rather than the whole person. The goal of this report was to communicate the benefits of a holistic approach to the treatment and recovery of stroke. Our intent was to begin a conversation to transform our approach to stroke care to focus on the whole person, body, mind, and spirit. Wellness approaches are fiscally responsible ways of providing holistic care for patients and their family members to help them achieve optimal individualized recovery. Very few multidimensional programs for wellness exist for patients with stroke and brain injury. Given the changes in health care and the Call to Action set forth in the Institute of Medicine's 2010 report, it would behoove us to consider holistic approaches to stroke care and research programs. Nurses are uniquely positioned to implement multidisciplinary, innovative holistic approaches to address solutions for issues in stroke care. Wellness is a critically important area of stroke care and an opportunity for research. As advocates for patients, and nurses with personal experiences, we hope this commentary stimulates conversation around developing and testing multidimensional holistic programs of wellness for stroke prevention, treatment, and recovery.

  12. The integrated approach methodology for operator information evaluation

    International Nuclear Information System (INIS)

    Stroube, K.; Modarres, M.; Roush, M.; Hunt, N.; Pearce, R.

    1986-01-01

    The Integrated Approach has developed a complete method for evaluating the relative importance of operation information improvements. By use of decision trees the impact of information on success probability of a function or system can be evaluated. This approach couples goal trees and human success likelihoods to estimate anticipated consequences of a given information system

  13. Towards an integrated approach to health and medicine in Africa

    African Journals Online (AJOL)

    2016-08-18

    Aug 18, 2016 ... As such, a social approach to health-seeking behaviour questions how decisions ... In conclusion, the paper proposes that medicine and the humanities should engage seriously .... mental questions: What story does the integration or separation .... approach which has taken an interest in traditional healing.

  14. Learning about the Weather through an Integrated STEM Approach

    Science.gov (United States)

    Serin, Gokhan

    2014-01-01

    Introducing concepts through an integrated science, technology, engineering and mathematics (STEM) approach can promote interest and motivation (Bennett, Lubben and Hogarth, 2007; Bybee, 2010). However, implementing such an approach effectively in a classroom setting, with relevant links, is a challenging task. Some concepts lend themselves more…

  15. An integrated artificial neural networks approach for predicting global radiation

    International Nuclear Information System (INIS)

    Azadeh, A.; Maghsoudi, A.; Sohrabkhani, S.

    2009-01-01

    This article presents an integrated artificial neural network (ANN) approach for predicting solar global radiation by climatological variables. The integrated ANN trains and tests data with multi layer perceptron (MLP) approach which has the lowest mean absolute percentage error (MAPE). The proposed approach is particularly useful for locations where no available measurement equipment. Also, it considers all related climatological and meteorological parameters as input variables. To show the applicability and superiority of the integrated ANN approach, monthly data were collected for 6 years (1995-2000) in six nominal cities in Iran. Separate model for each city is considered and the quantity of solar global radiation in each city is calculated. Furthermore an integrated ANN model has been introduced for prediction of solar global radiation. The acquired results of the integrated model have shown high accuracy of about 94%. The results of the integrated model have been compared with traditional angstrom's model to show its considerable accuracy. Therefore, the proposed approach can be used as an efficient tool for prediction of solar radiation in the remote and rural locations with no direct measurement equipment.

  16. Integrated, regional approach to risk management of industrial systems

    International Nuclear Information System (INIS)

    Chakraborty, S.

    1992-01-01

    This paper focuses on the following four main issues: (1) necessity for an integrated, regional approach to risk management of industrial systems; (2) principles of risk management; (3) integrated approach and overall methodology; and (4) implementation of risk management strategies on a regional basis. The U.N. Interagency project on risk management for large industrial areas, which is a pioneer type of international initiative for an integrated approach to risk management, is discussed in this context. Another encouraging activity for further development of overall methodologies for risk management is the ongoing project on the risk and safety of technical systems at the Swiss Federal Institute of Technology in Aurich. The concept of integral risk management takes into account multidimensional factors including technical, economic, political, social, and ethical considerations to allow a well-balanced decision-making process

  17. Recent developments in the path integral approach to anomalies

    International Nuclear Information System (INIS)

    Fujikawa, Kazuo.

    1986-08-01

    After a brief summary of the path integral approach to anomalous identities, some of the recent developments in this approach are discussed. The topics discussed include (i) Construction of the effective action by means of the covariant current, (ii) Gauss law constraint in anomalous gauge theories, (iii) Path integral approach to anomalies in superconformal transformations, (iv) Conformal and ghost number anomalies in string theory in analogy with the instanton calculation, (v) Covariant local Lorentz anomaly and its connection with the mathematical construction of the consistent anomaly. (author)

  18. High resolution integral holography using Fourier ptychographic approach.

    Science.gov (United States)

    Li, Zhaohui; Zhang, Jianqi; Wang, Xiaorui; Liu, Delian

    2014-12-29

    An innovative approach is proposed for calculating high resolution computer generated integral holograms by using the Fourier Ptychographic (FP) algorithm. The approach initializes a high resolution complex hologram with a random guess, and then stitches together low resolution multi-view images, synthesized from the elemental images captured by integral imaging (II), to recover the high resolution hologram through an iterative retrieval with FP constrains. This paper begins with an analysis of the principle of hologram synthesis from multi-projections, followed by an accurate determination of the constrains required in the Fourier ptychographic integral-holography (FPIH). Next, the procedure of the approach is described in detail. Finally, optical reconstructions are performed and the results are demonstrated. Theoretical analysis and experiments show that our proposed approach can reconstruct 3D scenes with high resolution.

  19. An Overview of Modeling Approaches Applied to Aggregation-Based Fleet Management and Integration of Plug-in Electric Vehicles †

    DEFF Research Database (Denmark)

    You, Shi; Hu, Junjie; Ziras, Charalampos

    2016-01-01

    The design and implementation of management policies for plug-in electric vehicles (PEVs) need to be supported by a holistic understanding of the functional processes, their complex interactions, and their response to various changes. Models developed to represent different functional processes...... and systems are seen as useful tools to support the related studies for different stakeholders in a tangible way. This paper presents an overview of modeling approaches applied to support aggregation-based management and integration of PEVs from the perspective of fleet operators and grid operators......, respectively. We start by explaining a structured modeling approach, i.e., a flexible combination of process models and system models, applied to different management and integration studies. A state-of-the-art overview of modeling approaches applied to represent several key processes, such as charging...

  20. Evaluating the use of an integrated approach to support energy and climate policy formulation and evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Bassi, A. M. [Millennium Institute, 2111 Wilson Blvd, Suite 700, Arlington, VA 22201 (United States)

    2010-09-15

    With the adoption of the Kyoto Protocol in 1997 national leaders have started investigating options for reducing carbon emissions within national borders. Despite confronting similar energy issues, every country that adopted the Kyoto Protocol has a unique energy strategy - being characterized by a different context, social, economic or environmental that influences the way different nations deal with climate change and other energy-related issues. Finding that currently available energy models are often too detailed or narrowly focused to inform longer-term policy formulation and evaluation holistically, the present study proposes the utilization of an integrated cross-sectoral medium to longer-term research and modeling approach, incorporating various methodologies to minimize exogenous assumptions and endogenously represent the key drivers of the system analyzed. The framework proposed includes feedback, delays and non-linearity and focuses on structure, scenarios and policies, requires a profound customization of the model that goes beyond a new parameterization. The inclusion of social and environmental factors, in addition to economic ones, all unique to the geographical area analyzed, allows for a wider analysis of the implication of policies by identifying potential side effect or longer-term bottlenecks for socio-economic development and environmental preservation arising from cross-sectoral relations. (author)